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Sample records for act nepa characterization

  1. Hanford Site National Environmental Policy Act (NEPA) characterization. Revision 9

    International Nuclear Information System (INIS)

    This ninth revision of the Hanford Site National Environmental Policy Act (NEPA) Characterization presents current environmental data regarding the hanford Site and its immediate environs. This information is intended for use in preparing Chapters 4 and 6 in Hanford Site-related NEPA documents. Chapter 4.0 (Affected Environment) includes information on climate and meteorology, geology, hydrology, ecology, cultural, archaeological and historical resources, socioeconomics, and noise. Chapter 6.0 (Statutory and Regulatory Requirements) provides the preparer with the federal and state regulations, DOE directives and permits, and environmental standards directly applicable to the NEPA documents on the Hanford Site. Not all of the sections have been updated for this revision. The following lists the updated sections: climate and meteorology; ecology (threatened and endangered species section only); culture, archaeological, and historical resources; socioeconomics; all of Chapter 6

  2. Hanford Site National Environmental Policy Act (NEPA) characterization. Revision 9

    Energy Technology Data Exchange (ETDEWEB)

    Neitzel, D.A. [ed.; Bjornstad, B.N.; Fosmire, C.J. [and others

    1997-08-01

    This ninth revision of the Hanford Site National Environmental Policy Act (NEPA) Characterization presents current environmental data regarding the hanford Site and its immediate environs. This information is intended for use in preparing Chapters 4 and 6 in Hanford Site-related NEPA documents. Chapter 4.0 (Affected Environment) includes information on climate and meteorology, geology, hydrology, ecology, cultural, archaeological and historical resources, socioeconomics, and noise. Chapter 6.0 (Statutory and Regulatory Requirements) provides the preparer with the federal and state regulations, DOE directives and permits, and environmental standards directly applicable to the NEPA documents on the Hanford Site. Not all of the sections have been updated for this revision. The following lists the updated sections: climate and meteorology; ecology (threatened and endangered species section only); culture, archaeological, and historical resources; socioeconomics; all of Chapter 6.

  3. Hanford Site National Environmental Policy Act (NEPA) characterization. Revision 8

    Energy Technology Data Exchange (ETDEWEB)

    Neitzel, D.A. [ed.; Bjornstad, B.N.; Fosmire, C.J.; Fowler, R.A. [and others

    1996-08-01

    This eighth revision of the Hanford Site National Environmental Policy Act (NEPA) Characterization presents current environmental data regarding the Hanford Site and its immediate environs. This information is intended for use in preparing Chapters 4 and 6 in Hanford Site-related NEPA documents. Chapter 4 (Affected Environment) includes information on climate and meteorology, geology, hydrology, ecology, historical, archaeological and cultural resources, socioeconomics, and noise. Chapter 6 (Statutory and Regulatory Requirements) provides the preparer with the federal and state regulations, DOE directives and permits, and environmental standards directly applicable to the NEPA documents on the Hanford Site. The following sections were updated in this revision: climate and meteorology; ecology (threatened and endangered species section only); historical; archaeological and cultural resources; and all of chapter 6. No conclusions or recommendations are given in this report. Rather, it is a compilation of information on the Hanford Site environment that can be used directly by Site contractors. This information can also be used by any interested individual seeking baseline data on the hanford Site and its past activities by which to evaluate projected activities and their impacts.

  4. Hanford Site National Environmental Policy Act (NEPA) characterization. Revision 8

    International Nuclear Information System (INIS)

    This eighth revision of the Hanford Site National Environmental Policy Act (NEPA) Characterization presents current environmental data regarding the Hanford Site and its immediate environs. This information is intended for use in preparing Chapters 4 and 6 in Hanford Site-related NEPA documents. Chapter 4 (Affected Environment) includes information on climate and meteorology, geology, hydrology, ecology, historical, archaeological and cultural resources, socioeconomics, and noise. Chapter 6 (Statutory and Regulatory Requirements) provides the preparer with the federal and state regulations, DOE directives and permits, and environmental standards directly applicable to the NEPA documents on the Hanford Site. The following sections were updated in this revision: climate and meteorology; ecology (threatened and endangered species section only); historical; archaeological and cultural resources; and all of chapter 6. No conclusions or recommendations are given in this report. Rather, it is a compilation of information on the Hanford Site environment that can be used directly by Site contractors. This information can also be used by any interested individual seeking baseline data on the hanford Site and its past activities by which to evaluate projected activities and their impacts

  5. Hanford Site National Environmental Policy Act (NEPA) Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Neitzel, Duane A.; Bunn, Amoret L.; Duncan, Joanne P.; Eschbach, Tara O.; Fowler, Richard A.; Fritz, Brad G.; Goodwin, Shannon M.; Harvey, David W.; Hendrickson, Paul L.; Hoitink, Dana J.; Horton, Duane G.; Last, George V.; Poston, Ted M.; Prendergast-Kennedy, Ellen L.; Rohay, Alan C.; Scott, Michael J.; Thorne, Paul D.

    2002-09-01

    This document describes the U.S. Department of Energy's (DOE) Hanford Site environment. It is updated each year and is intended to provide a consistent description of the Hanford Site environment for the many National Environmental Policy Act (NEPA) documents being prepared by DOE contractors. No statements of significance or environmental consequences are provided. This year's report is the thirteenth revision of the original document published in 1988 and is (until replaced by the fourteenth revision) the only version that is relevant for use in the preparation of Hanford NEPA, State Environmental Policy Act (SEPA), and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) documents. The two chapters included in this document (Chapters 4 and 6) are numbered to correspond to the chapters where such information is typically presented in environmental impact statements (Weiss) and other Hanford Site NEPA or CERCLA documentation. Chapter 4.0 (Affected Environment) describes Hanford Site climate and meteorology, geology, hydrology, ecology, cultural, archaeological, and historical resources, socioeconomics, occupational safety, and noise. Chapter 6.0 (Statutory and Regulatory Requirements) describes federal and state laws and regulations, DOE directives and permits, and presidential executive orders that are applicable to the NEPA documents prepared for Hanford Site activities.

  6. Hanford Site National Environmental Policy Act (NEPA) Characterization Report

    Energy Technology Data Exchange (ETDEWEB)

    Neitzel, Duane A.; Bunn, Amoret L.; Cannon, Sandra D.; Duncan, Joanne P.; Fowler, Richard A.; Fritz, Brad G.; Harvey, David W.; Hendrickson, Paul L.; Hoitink, Dana J.; Horton, Duane G.; Last, George V.; Poston, Ted M.; Prendergast-Kennedy, Ellen L.; Reidel, Steve P.; Rohay, Alan C.; Scott, Michael J.; Thorne, Paul D.

    2004-09-22

    This document describes the U.S. Department of Energy's (DOE) Hanford Site environment. It is updated each year and is intended to provide a consistent description of the Hanford Site environment for the many National Environmental Policy Act (NEPA) documents being prepared by DOE contractors. No statements of significance or environmental consequences are provided. This year's report is the sixteenth revision of the original document published in 1988 and is (until replaced by the seventeenth revision) the only version that is relevant for use in the preparation of Hanford NEPA, State Environmental Policy Act (SEPA), and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) documents. The two chapters included in this document (Chapters 4 and 6) are numbered to correspond to the chapters where such information is typically presented in environmental impact statements (Weiss) and other Hanford Site NEPA or CERCLA documentation. Chapter 4.0 (Affected Environment) describes Hanford Site climate and meteorology, geology, hydrology, ecology, cultural, archaeological, and historical resources, socioeconomics, occupational safety and health, and noise. Chapter 6.0 (Statutory and Regulatory Requirements) describes federal and state laws and regulations, DOE directives and permits, and presidential executive orders that are applicable to the NEPA documents prepared for Hanford Site activities.

  7. Hanford Site National Environmental Policy Act (NEPA) Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Neitzel, Duane A.; Antonio, Ernest J.; Eschbach, Tara O.; Fowler, Richard A.; Goodwin, Shannon M.; Harvey, David W.; Hendrickson, Paul L.; Hoitink, Dana J.; Horton, Duane G.; Last, George V.; Poston, Ted M.; Prendergast, Ellen L.; Rohay, Alan C.; Thorne, Paul D.

    2001-09-01

    This document describes the U.S. Department of Energy's (DOE) Hanford Site environment. It is updated each year and is intended to provide a consistent description of the Hanford Site environment for the many National Environmental Policy Act (NEPA) documents being prepared by DOE contractors. No statements of significance or environmental consequences are provided. This year's report is the thirteenth revision of the original document published in 1988 and is (until replaced by the fourteenth revision) the only version that is relevant for use in the preparation of Hanford NEPA, State Environmental Policy Act (SEPA), and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) documents. The two chapters included in this document (Chapters 4 and 6) are numbered to correspond to the chapters where such information is typically presented in environmental impact statements (Weiss) and other Hanford Site NEPA or CERCLA documentation. Chapter 4.0 (Affected Environment) describes Hanford Site climate and meteorology, geology, hydrology, ecology, cultural, archaeological, and historical resources, socioeconomics, occupational safety, and noise. Chapter 6.0 (Statutory and Regulatory Requirements) describes federal and state laws and regulations, DOE directives and permits, and presidential executive orders that are applicable to the NEPA documents prepared for Hanford Site activities.

  8. Hanford Site National Environmental Policy Act (NEPA) Characterization, Revision 15

    Energy Technology Data Exchange (ETDEWEB)

    Neitzel, Duane A.; Bunn, Amoret L.; Burk, Kenneth W.; Cannon, Sandra D.; Duncan, Joanne P.; Fowler, Richard A.; Fritz, Brad G.; Harvey, David W.; Hendrickson, Paul L.; Horton, Duane G.; Last, George V.; Poston, Ted M.; Prendergast-Kennedy, Ellen L.; Reidel, Steve P.; Scott, Michael J.; Thorne, Paul D.; Woody, Dave M.

    2003-09-01

    This document describes the U.S. Department of Energy's (DOE) Hanford Site environment. It is updated each year and is intended to provide a consistent description of the Hanford Site environment for the many National Environmental Policy Act (NEPA) documents being prepared by DOE contractors. No statements of significance or environmental consequences are provided. This year's report is the thirteenth revision of the original document published in 1988 and is (until replaced by the fourteenth revision) the only version that is relevant for use in the preparation of Hanford NEPA, State Environmental Policy Act (SEPA), and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) documents. The two chapters included in this document (Chapters 4 and 6) are numbered to correspond to the chapters where such information is typically presented in environmental impact statements (Weiss) and other Hanford Site NEPA or CERCLA documentation. Chapter 4.0 (Affected Environment) describes Hanford Site climate and meteorology, geology, hydrology, ecology, cultural, archaeological, and historical resources, socioeconomics, occupational safety, and noise. Chapter 6.0 (Statutory and Regulatory Requirements) describes federal and state laws and regulations, DOE directives and permits, and presidential executive orders that are applicable to the NEPA documents prepared for Hanford Site activities.

  9. Hanford Site National Environmental Policy Act (NEPA) Characterization

    International Nuclear Information System (INIS)

    This fifth revision of the Hanford Site National Environmental Policy (NEPA) Characterization presents current environmental data regarding the Hanford Site and its immediate environs. This information is intended for use in preparing Site-related NEPA documentation. Information is presented on climate and meteorology, geology and hydrology, ecology, history and archaeology, socioeconomics, land use, and noise levels, prepared by Pacific Northwest Laboratory (PNL) staff. Models are described that are to be used in simulating realized or potential impacts from nuclear materials at the Hanford Site. Included are models of radionuclide transport in groundwater and atmospheric pathways, and of radiation dose to populations via all known pathways from known initial conditions. Federal and state regulations, DOE orders and permits, and environmental standards directly applicable for the NEPA documents at the Hanford Site, are provided

  10. Hanford Site National Environmental Policy Act (NEPA) Characterization. Revision 5

    Energy Technology Data Exchange (ETDEWEB)

    Cushing, C.E. [ed.

    1992-12-01

    This fifth revision of the Hanford Site National Environmental Policy (NEPA) Characterization presents current environmental data regarding the Hanford Site and its immediate environs. This information is intended for use in preparing Site-related NEPA documentation. Information is presented on climate and meteorology, geology and hydrology, ecology, history and archaeology, socioeconomics, land use, and noise levels, prepared by Pacific Northwest Laboratory (PNL) staff. Models are described that are to be used in simulating realized or potential impacts from nuclear materials at the Hanford Site. Included are models of radionuclide transport in groundwater and atmospheric pathways, and of radiation dose to populations via all known pathways from known initial conditions. Federal and state regulations, DOE orders and permits, and environmental standards directly applicable for the NEPA documents at the Hanford Site, are provided.

  11. Hanford Site National Environmental Policy Act (NEPA) Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Cushing, C.E. (ed.)

    1992-12-01

    This fifth revision of the Hanford Site National Environmental Policy (NEPA) Characterization presents current environmental data regarding the Hanford Site and its immediate environs. This information is intended for use in preparing Site-related NEPA documentation. Information is presented on climate and meteorology, geology and hydrology, ecology, history and archaeology, socioeconomics, land use, and noise levels, prepared by Pacific Northwest Laboratory (PNL) staff. Models are described that are to be used in simulating realized or potential impacts from nuclear materials at the Hanford Site. Included are models of radionuclide transport in groundwater and atmospheric pathways, and of radiation dose to populations via all known pathways from known initial conditions. Federal and state regulations, DOE orders and permits, and environmental standards directly applicable for the NEPA documents at the Hanford Site, are provided.

  12. Hanford Site National Environmental Policy Act (NEPA) characterization

    Energy Technology Data Exchange (ETDEWEB)

    Cushing, C.E. (ed.)

    1988-09-01

    This document describes the Hanford Site environment (Chapter 4) and contains data in Chapter 5 and 6 which will guide users in the preparation of National Environmental Policy Act (NEPA)-related documents. Many NEPA compliance documents have been prepared and are being prepared by site contractors for the US Department of Energy, and examination of these documents reveals inconsistencies in the amount of detail presented and the method of presentation. Thus, it seemed necessary to prepare a consistent description of the Hanford environment to be used in preparing Chapter 4 of environmental impact statements and other site-related NEPA documentation. The material in Chapter 5 is a guide to the models used, including critical assumptions incorporated in these models, in previous Hanford NEPA documents. The users will have to select those models appropriate for the proposed action. Chapter 6 is essentially a definitive NEPA Chapter 6, which describes the applicable laws, regulations, and DOE and state orders. In this document, a complete description of the environment is presented in Chapter 4 without excessive tabular data. For these data, sources are provided. Most subjects are divided into a general description of the characteristics of the Hanford Site, followed by site-specific information where it is available on the 100, 200, 300, and other Areas. This division will allow a person requiring information to go immediately to those sections of particular interest. However, site-specific information on each of these separate areas is not always complete or available. In this case, the general Hanford Site description should be used. 131 refs., 19 figs., 32 tabs.

  13. Hanford Site National Environmental Policy Act (NEPA) Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Duncan, Joanne P.; Burk, Kenneth W.; Chamness, Mickie A.; Fowler, Richard A.; Fritz, Brad G.; Hendrickson, Paul L.; Kennedy, Ellen P.; Last, George V.; Poston, Ted M.; Sackschewsky, Michael R.; Scott, Michael J.; Snyder, Sandra F.; Sweeney, Mark D.; Thorne, Paul D.

    2007-09-27

    This document describes the U.S. Department of Energy’s (DOE) Hanford Site environment. It is intended to provide a consistent description of the Hanford Site for the many environmental documents being prepared by DOE contractors concerning the National Environmental Policy Act (NEPA). No statements regarding significance or environmental consequences are provided. This year’s report is the eighteen revision of the original document published in 1988 and is (until replaced by the nineteenth revision) the only version that is relevant for use in the preparation of Hanford NEPA, State Environmental Policy Act (SEPA), and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) documents. Two chapters are included in this document (Chapters 4 and 6), numbered to correspond to chapters typically presented in environmental impact statements (EISs) and other Hanford Site NEPA or CERCLA documentation. Chapter 4.0 (Affected Environment) describes Hanford Site climate and meteorology; air quality; geology; hydrology; ecology; cultural, archaeological, and historical resources; socioeconomics; noise; and occupational health and safety. Sources for extensive tabular data related to these topics are provided in the chapter. When possible, subjects are divided into a general description of the characteristics of the Hanford Site, followed by site-specific information, where available, for the 100, 200, 300 and other areas. This division allows the reader to go directly to those sections of particular interest. When specific information on each of these separate areas is not complete or available, the general Hanford Site description should be used. Chapter 6.0 (Statutory and Regulatory Requirements) describes federal and state laws and regulations, DOE directives and permits, and presidential executive orders that are applicable to NEPA documents prepared for Hanford Site activities. Information in Chapter 6 can be adapted and supplemented with

  14. Hanford Site National Environmental Policy Act (NEPA) characterization. Revision 7

    Energy Technology Data Exchange (ETDEWEB)

    Cushing, C.E. [ed.; Baker, D.A.; Chamness, M.A. [and others

    1995-09-01

    This seventh revision of the Hanford Site National Environmental Policy (NEPA) Characterization presents current environmental data regarding the Hanford Site and its immediate environs. This information is intended for use in preparing Site-related NEPA documentation. Chapter 4.0 summarizes up-to-date information on climate and meteorology, geology, hydrology, environmental monitoring, ecology, history and archaeology, socioeconomics, land use, and noise levels prepared by Pacific Northwest Laboratory (PNL) staff. More detailed data are available from reference sources cited or from the authors. Chapter 5.0 was not updated from the sixth revision (1994). It describes models, including their principal underlying assumptions, that are to be used in simulating realized or potential impacts from nuclear materials at the Hanford Site. Included are models of radionuclide transport in groundwater and atmospheric pathways, and of radiation dose to populations via all known pathways from known initial conditions. The updated Chapter 6.0 provides the preparer with the federal and state regulations, DOE Orders and permits, and environmental standards directly applicable to the NEPA documents on the Hanford Site, following the structure of Chapter 4.0. No conclusions or recommendations are given in this report. Rather, it is a compilation of information on the Hanford Site environment that can be used directly by Site contractors. This information can also be used by any interested individual seeking baseline data on the Hanford Site and its past activities by which to evaluate projected activities and their impacts.

  15. Hanford Site National Environmental Policy Act (NEPA) characterization. Revision 6

    Energy Technology Data Exchange (ETDEWEB)

    Cushing, C.E. [ed.; Baker, D.A.; Chamness, M.A. [and others

    1994-08-01

    This sixth revision of the Hanford Site National Environmental Policy (NEPA) Characterization presents current environmental data regarding the Hanford Site and its immediate environs. This information is intended for use in preparing Site-related NEPA documentation. Chapter 4.0 summarizes up-to-date information on climate and meteorology, geology and hydrology, ecology, history and archaeology, socioeconomics, land use, and noise levels prepared by Pacific Northwest Laboratory (PNL) staff. More detailed data are available from reference sources cited or from the authors; Chapter 5.0 has been significantly updated from the fifth revision. It describes models, including their principal underlying assumptions, that are to be used in simulating realized or potential impacts from nuclear materials at the Hanford Site. Included are models of radionuclide transport in groundwater and atmospheric pathways, and of radiation dose to populations via all known pathways from known initial conditions; The updated Chapter 6.0 provides the preparer with the federal and state regulations, DOE orders and permits, and environmental standards directly applicable to the NEPA documents on the Hanford Site, following the structure of Chapter 4.0. No conclusions or recommendations are given in this report. Rather, it is a compilation of information on the Hanford Site environment that can be utilized directly by Site contractors. This information can also be used by any interested individual seeking baseline data on the Hanford Site and its past activities by which to evaluate projected activities and their impacts.

  16. Hanford Site National Environmental Policy Act (NEPA) characterization. Revision 6

    International Nuclear Information System (INIS)

    This sixth revision of the Hanford Site National Environmental Policy (NEPA) Characterization presents current environmental data regarding the Hanford Site and its immediate environs. This information is intended for use in preparing Site-related NEPA documentation. Chapter 4.0 summarizes up-to-date information on climate and meteorology, geology and hydrology, ecology, history and archaeology, socioeconomics, land use, and noise levels prepared by Pacific Northwest Laboratory (PNL) staff. More detailed data are available from reference sources cited or from the authors; Chapter 5.0 has been significantly updated from the fifth revision. It describes models, including their principal underlying assumptions, that are to be used in simulating realized or potential impacts from nuclear materials at the Hanford Site. Included are models of radionuclide transport in groundwater and atmospheric pathways, and of radiation dose to populations via all known pathways from known initial conditions; The updated Chapter 6.0 provides the preparer with the federal and state regulations, DOE orders and permits, and environmental standards directly applicable to the NEPA documents on the Hanford Site, following the structure of Chapter 4.0. No conclusions or recommendations are given in this report. Rather, it is a compilation of information on the Hanford Site environment that can be utilized directly by Site contractors. This information can also be used by any interested individual seeking baseline data on the Hanford Site and its past activities by which to evaluate projected activities and their impacts

  17. Hanford Site National Evnironmental Policy Act (NEPA) characterization. Revision 4

    Energy Technology Data Exchange (ETDEWEB)

    Cushing, C.E. [ed.

    1991-12-01

    This fourth revision of the Hanford Site National Environmental Policy (NEPA) Characterization presents current environmental data regarding the Hanford Site and its immediate environs. This information is intended for use in preparing Site-related NEPA documentation. In Chapter 4.0 are presented summations of up-to-date information about climate and meteorology, geology and hydrology, ecology, history and archaeology, socioeconomics, land use, and noise levels. Chapter 5.0 describes models, including their principal assumptions, that are to be used in simulating realized or potential impacts from nuclear materials at the Hanford Site. Included are models of radionuclides transport in groundwater and atmospheric pathways, and of radiation dose to populations via all known pathways from known initial conditions. Chapter 6.0 provides the preparer with the federal and state regulations, DOE orders and permits, and environmental standards directly applicable for environmental impact statements for the Hanford Site, following the structure Chapter 4.0. NO conclusions or recommendations are given in this report.

  18. Hanford Site National Evnironmental Policy Act (NEPA) characterization

    Energy Technology Data Exchange (ETDEWEB)

    Cushing, C.E. (ed.)

    1991-12-01

    This fourth revision of the Hanford Site National Environmental Policy (NEPA) Characterization presents current environmental data regarding the Hanford Site and its immediate environs. This information is intended for use in preparing Site-related NEPA documentation. In Chapter 4.0 are presented summations of up-to-date information about climate and meteorology, geology and hydrology, ecology, history and archaeology, socioeconomics, land use, and noise levels. Chapter 5.0 describes models, including their principal assumptions, that are to be used in simulating realized or potential impacts from nuclear materials at the Hanford Site. Included are models of radionuclides transport in groundwater and atmospheric pathways, and of radiation dose to populations via all known pathways from known initial conditions. Chapter 6.0 provides the preparer with the federal and state regulations, DOE orders and permits, and environmental standards directly applicable for environmental impact statements for the Hanford Site, following the structure Chapter 4.0. NO conclusions or recommendations are given in this report.

  19. Hanford Site National Environmental Policy Act (NEPA) characterization. Revision 10

    International Nuclear Information System (INIS)

    This document describes the US Department of Energy's (DOE) Hanford Site environment and is numbered to correspond to the chapters where such information is presented in Hanford Site NEPA related documents. The document is intended to provide a consistent description of the Hanford Site environment for the many NEPA documents that are being prepared by contractors. The two chapters in this document (Chapters 4 and 6) are numbered this way to correspond to the chapters where such information is presented in environmental impact statements (EISs) and other Site-related NEPA or CERCLA documentation. Chapter 4.0 (Affected Environment) describes the Hanford Site environment, and includes information on climate and meteorology, geology, hydrology, ecology, cultural, archaeological and historical resources, socioeconomics, and noise. Chapter 6.0 (Statutory and Regulatory Requirements) describes applicable federal and state laws and regulations, DOE directives and permits, and environmental standards directly applicable to the NEPA documents on the Hanford Site

  20. Hanford Site National Environmental Policy Act (NEPA) characterization. Revision 10

    Energy Technology Data Exchange (ETDEWEB)

    Neitzel, D.A. [ed.; Fosmire, C.J.; Fowler, R.A. [and others

    1998-09-01

    This document describes the US Department of Energy`s (DOE) Hanford Site environment and is numbered to correspond to the chapters where such information is presented in Hanford Site NEPA related documents. The document is intended to provide a consistent description of the Hanford Site environment for the many NEPA documents that are being prepared by contractors. The two chapters in this document (Chapters 4 and 6) are numbered this way to correspond to the chapters where such information is presented in environmental impact statements (EISs) and other Site-related NEPA or CERCLA documentation. Chapter 4.0 (Affected Environment) describes the Hanford Site environment, and includes information on climate and meteorology, geology, hydrology, ecology, cultural, archaeological and historical resources, socioeconomics, and noise. Chapter 6.0 (Statutory and Regulatory Requirements) describes applicable federal and state laws and regulations, DOE directives and permits, and environmental standards directly applicable to the NEPA documents on the Hanford Site.

  1. Hanford Site National Environmental Policy Act (NEPA) Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Rohay, A.C.; Fosmire, C.J.; Neitzel, D.A.; Hoitink, D.J.; Harvey, D.W.; Antonio, E.J.; Wright, M.K.; Thorne, P.D.; Hendrickson, P.L.; Fowler, R.A.; Goodwin, S.M.; Poston, T.M.

    1999-09-28

    This document describes the US Department of Energy's (DOE) Hanford Site environment. It is updated each year and is intended to provide a consistent description of the Hanford Site environment for the many NEPA documents being prepared by DOE contractors. No conclusions or recommendations are provided. This year's report is the eleventh revision of the original document published in 1988 and is (until replaced by the 12th revision) the only version that is relevant for use in the preparation of Hanford NEPA; SEPA and CERCLA documents. The two chapters included in this document (Chapters 4 and 6) are numbered to correspond to the chapters where such information is presented in environmental impact statements (EISs) and other Site-related NEPA or CERCLA documentation. Chapter 4.0 (Affected Environment) describes Hanford Site climate and meteorology, geology, hydrology, ecology, cultural, archaeological and historical resources, socioeconomic; occupational safety, and noise. Sources for extensive tabular data related to these topics are provided in the chapter. Most subjects are divided into a general description of the characteristics of the Hanford Site, followed by site-specific information, where available, of the 100,200,300, and other Areas. This division allows the reader to go directly to those sections of particular interest. When specific information on each of these separate areas is not complete or available, the general Hanford Site description should be used. Chapter 6.0 (Statutory and Regulatory Requirements) is essentially a definitive NEPA Chapter 6.0, which describes applicable federal and state laws and regulations, DOE directives and permits, and environmental standards directly applicable to the NEPA documents on the Hanford Site. People preparing environmental assessments and EISs should also be cognizant of the document entitled ''Recommendations for the Preparation of Environmental Assessments and Environmental Impact

  2. Hanford Site National Environmental Policy Act (NEPA) Characterization Report, Revision 17

    Energy Technology Data Exchange (ETDEWEB)

    Neitzel, Duane A.; Bunn, Amoret L.; Cannon, Sandra D.; Duncan, Joanne P.; Fowler, Richard A.; Fritz, Brad G.; Harvey, David W.; Hendrickson, Paul L.; Hoitink, Dana J.; Horton, Duane G.; Last, George V.; Poston, Ted M.; Prendergast-Kennedy, Ellen L.; Reidel, Steve P.; Rohay, Alan C.; Sackschewsky, Michael R.; Scott, Michael J.; Thorne, Paul D.

    2005-09-30

    This document describes the U.S. Department of Energy’s (DOE) Hanford Site environment. It is updated each year and is intended to provide a consistent description of the Hanford Site environment for the many environmental documents being prepared by DOE contractors concerning the National Environmental Policy Act (NEPA). No statements about significance or environmental consequences are provided. This year’s report is the seventeenth revision of the original document published in 1988 and is (until replaced by the eighteenth revision) the only version that is relevant for use in the preparation of Hanford NEPA, State Environmental Policy Act (SEPA), and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) documents. The two chapters included in this document (Chapters 4 and 6) are numbered to correspond to the chapters where such information is typically presented in environmental impact statements (EISs) and other Hanford Site NEPA or CERCLA documentation. Chapter 4.0 (Affected Environment) describes Hanford Site climate and meteorology; air quality; geology; hydrology; ecology; cultural, archaeological, and historical resources; socioeconomics; noise; and occupational health and safety. Sources for extensive tabular data related to these topics are provided in the chapter. Most subjects are divided into a general description of the characteristics of the Hanford Site, followed by site-specific information, where available, of the 100, 200, 300, and other areas. This division allows the reader to go directly to those sections of particular interest. When specific information on each of these separate areas is not complete or available, the general Hanford Site description should be used. Chapter 6.0 (Statutory and Regulatory Requirements) describes federal and state laws and regulations, DOE directives and permits, and presidential executive orders that are applicable to the NEPA documents prepared for Hanford Site activities

  3. National Environmental Policy Act (NEPA) Compliance Guide, Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, R.P. [Hansen Environmental Consultants, Englewood, CO (United States)

    1995-08-01

    This report contains a comprehensive National Environmental Policy Act (NEPA) Compliance Guide for the Sandia National Laboratories. It is based on the Council on Environmental Quality (CEQ) NEPA regulations in 40 CFR Parts 1500 through 1508; the US Department of Energy (DOE) N-EPA implementing procedures in 10 CFR Part 102 1; DOE Order 5440.1E; the DOE ``Secretarial Policy Statement on the National Environmental Policy Act`` of June 1994- Sandia NEPA compliance procedures-, and other CEQ and DOE guidance. The Guide includes step-by-step procedures for preparation of Environmental Checklists/Action Descriptions Memoranda (ECL/ADMs), Environmental Assessments (EAs), and Environmental Impact Statements (EISs). It also includes sections on ``Dealing With NEPA Documentation Problems`` and ``Special N-EPA Compliance Issues.``

  4. Annotated bibliography National Environmental Policy Act (NEPA) documents for Sandia National Laboratories

    International Nuclear Information System (INIS)

    The following annotated bibliography lists documents prepared by the Department of Energy (DOE), and predecessor agencies, to meet the requirements of the National Environmental Policy Act (NEPA) for activities and facilities at Sandia National Laboratories sites. For each NEPA document summary information and a brief discussion of content is provided. This information may be used to reduce the amount of time or cost associated with NEPA compliance for future Sandia National Laboratories projects. This summary may be used to identify model documents, documents to use as sources of information, or documents from which to tier additional NEPA documents

  5. 75 FR 66774 - National Environmental Policy Act (NEPA) Implementing Procedures

    Science.gov (United States)

    2010-10-29

    ... competition, employment, investment, productivity, innovation, or the ability of U.S.-based enterprises to... procedures does not require NEPA analysis and documentation has been upheld in Heartwood, Inc. v. U.S. Forest... preparing NEPA documentation for a proposed action submitted by the Secretary. 7.3 Guidance to DHHL....

  6. National Environmental Policy Act (NEPA) compliance at Sandia National Laboratories/New Mexico (SNL/NM)

    Energy Technology Data Exchange (ETDEWEB)

    Wolff, T.A. [Sandia National Labs., Albuquerque, NM (United States). Community Involvement and Issues Management Dept.; Hansen, R.P. [Hansen Environmental Consultants, Englewood, CO (United States)

    1998-08-01

    This report on National Environmental Policy Act (NEPA) compliance at Sandia National Laboratories/New Mexico (SNL/NM) chronicles past and current compliance activities and includes a recommended strategy that can be implemented for continued improvement. This report provides a list of important references. Attachment 1 contains the table of contents for SAND95-1648, National Environmental Policy Act (NEPA) Compliance Guide Sandia National Laboratories (Hansen, 1995). Attachment 2 contains a list of published environmental assessments (EAs) and environmental impact statements (EISs) prepared by SNL/NM. Attachment 3 contains abstracts of NEPA compliance papers authored by SNL/NM and its contractors.

  7. National Environmental Policy Act (NEPA) compliance at Sandia National Laboratories/New Mexico (SNL/NM)

    International Nuclear Information System (INIS)

    This report on National Environmental Policy Act (NEPA) compliance at Sandia National Laboratories/New Mexico (SNL/NM) chronicles past and current compliance activities and includes a recommended strategy that can be implemented for continued improvement. This report provides a list of important references. Attachment 1 contains the table of contents for SAND95-1648, National Environmental Policy Act (NEPA) Compliance Guide Sandia National Laboratories (Hansen, 1995). Attachment 2 contains a list of published environmental assessments (EAs) and environmental impact statements (EISs) prepared by SNL/NM. Attachment 3 contains abstracts of NEPA compliance papers authored by SNL/NM and its contractors

  8. 42 CFR 137.287 - What is the National Environmental Policy Act (NEPA)?

    Science.gov (United States)

    2010-10-01

    ... procedures of the Act. CEQ regulations (40 CFR 1500-1508) establish three levels of environmental review... 42 Public Health 1 2010-10-01 2010-10-01 false What is the National Environmental Policy Act (NEPA... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction...

  9. National Environmental Policy Act (NEPA) Source Guide for the Hanford Site

    Energy Technology Data Exchange (ETDEWEB)

    JANSKY, M.T.

    2000-09-01

    This Source Guide will assist those working with the National Environmental Policy Act (NEPA) of 1969 to become more familiar with the environmental assessments (EA) and environmental impact statements (EIS) that apply to specific activities and facilities on the Hanford Site. This document should help answer questions concerning NEPA coverage, history, processes, and the status of many of the buildings and units on and related to the Hanford Site. This document summarizes relevant EAs and EISs by briefly outlining the proposed action of each document and the decision made by the U.S. Department of Energy (DOE) or its predecessor agencies, the U.S. Atomic Energy Commission (AEC) and the U.S. Energy Research and Development Administration (ERDA). The summary includes the proposed action alternatives and current status of the proposed action. If a decision officially was stated by the DOE, as in a finding of no significant impact (FONSI) or a record of decision (ROD), and the decision was located, a summary is provided. Not all federal decisions, such as FONSIs and RODs, can be found in the Federal Register (FR). For example, although significant large-action FONSIs can be found in the FR, some low-interest FONSIs might have been published elsewhere (i.e., local newspapers).

  10. Integrating NEPA [National Environmental Policy Act] and CERCLA [Comprehensive Environmental Response, Compensation, and Liability Act] requirements during remedial responses at DOE facilities

    International Nuclear Information System (INIS)

    US Department of Energy (DOE) Order 5400.4, issued October 6, 1989, calls for integrating the requirements of the National Environmental Policy Act (NEPA) with those of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) for DOE remedial actions under CERCLA. CERCLA requires that decisions on site remediation be made through a formal process called a Remedial Investigation/Feasibility Study (RI/FS). According to the DOE order, integration is to be accomplished by conducting the NEPA and CERCLA environmental planning and review procedures concurrently. The primary instrument for integrating the processes is to be the RI/FS process, which will be supplemented as needed to meet the procedural and documentational requirements of NEPA. The final product of the integrated process will be a single, integrated set of documents; namely, an RI report and an FS-EIS that satisfy the requirements of both NEPA and CERCLA. The contents of the report include (1) an overview and comparison of the requirements of the two processes; (2) descriptions of the major tasks included in the integrated RI/FS-EIS process; (3) recommended contents for integrated RI/FS-EIS documents; and (4)a discussion of some potential problems in integrating NEPA and CERCLA that fall outisde the scope of the RI/FS-EIS process, with suggestions for resolving some of these problems. 15 refs

  11. Successful implementation of the National Environmental Policy Act (NEPA) at a US Department of Energy (DOE) site: Environmental assessment preparation - a case study

    International Nuclear Information System (INIS)

    The U.S. Department of Energy (DOE) at Los Alamos National Laboratory (LANL) implements the requirements of the National Environmental Policy Act (NEPA) using a NEPA Compliance Team. The NEPA Compliance Team (Team) is composed of DOE Los Alamos Area Office (LAAO) and LANL employees that combine to create quality improvements in the DOE NEPA compliance process at both LAAO and LANL. A major focus of quality improvement has been in the area of Environmental Assessment (EA) documentation preparation. The NEPA Team within LANL's Ecology Group (ESH-20) is the organization responsible for preparing the EA documentation on behalf of DOE. DOE and LANL team in an interdisciplinary process to prepare review, and complete EAs using the technical expertise of individuals throughout the DOE and LANL. This approach has demonstrated significant time and cost savings as well as EA document quality improvements. The process used to prepare an EA for the Low Energy Demonstration Accelerator (LEDA) is presented as an example of a successful approach to implementing NEPA. The LEDA EA is used as a case study example to demonstrate how an integrated and interdisciplinary approach to conducting a NEPA analysis yields extremely successful results. The LEDA EA was prepared on an extremely aggressive schedule with tight cost constraints. The ESH-20 NEPA Team was successful in providing a critical link between the DOE decision-makers and the LEDA project representatives within LANL. As the technical scope of the LEDA project changed during the preparation of the EA, by emphasizing an interdisciplinary approach, the Team was able to quickly assess the implications and potential impacts through open communications with the various subject matter experts while maintaining a pace consistent with the EA schedule demands

  12. Molecular Characterization and Phylogenetic Analysis of Novel Isoform of Anti-lipopolysaccharide Factor from the Mantis Shrimp, Miyakea nepa.

    Science.gov (United States)

    Sruthy, K S; Chaithanya, E R; Sathyan, Naveen; Nair, Aishwarya; Antony, Swapna P; Singh, I S Bright; Philip, Rosamma

    2015-12-01

    Anti-lipopolysaccharide factor (ALF) is a cationic anti-microbial peptide representing humoral defence system exhibiting a diverse spectrum of activity against microbial pathogens, including gram-negative and gram-positive bacteria, fungi, parasites and viruses. In this study, we identified and characterized a novel ALF homologue (MnALF) encoding cDNA sequence from the haemocytes of stomatopod mantis shrimp Miyakea nepa. The deduced peptide of MnALF encoded for a 123-amino acid peptide with a 25-residue signal peptide containing selenocysteine followed by a highly cationic mature peptide comprised of a putative LPS-binding domain flanked by two cysteine residues. BLAST analysis of MnALF showed that it exhibits identity to crustacean and limulid ALFs. The mature peptide of MnALF has a net charge of +7 and predicted molecular weight of 10.998 kDa with a theoretical isoelectric point (pI) of 9.93. Spatial structure of MnALF comprises three α-helices packed against a four-stranded β-sheet of which two were linked by a disulphide bond to form an amphipathic loop similar to the structure of Penaeus monodon, ALF-Pm3. All these features suggest that MnALF could play an imperative role in the innate defence mechanism of M. nepa. To our knowledge, this study accounts for the first report of an anti-microbial peptide from the order stomatopoda. PMID:26187684

  13. Oak Ridge National Laboratory's philosophy and approach to NEPA

    International Nuclear Information System (INIS)

    At Oak Ridge National Laboratory (ORNL), the overall responsibility for compliance with the National Environmental Policy Act (NEPA) resides with Environmental Review and Documentations Section that is within the Office of Environmental Compliance and Documentation (OECD). Organizationally, OECD is a line-management division reporting to the Director for Environmental, Safety and Health Compliance. The cornerstone for NEPA compliance at ORNL is the Internal Environmental Assessment (IEA), which is designed to provide a basis for NEPA review and documentation. The Standard Operating Procedures provide for evaluation and documentation records management and training, and auditing. The IEA provides a project description and a review of environmental, health and safety issues. The completed IEA is used to make recommendations to DOE regarding the appropriate level of NEPA documentation required for the action. NEPA documents which may be prepared include the Categorical Exclusion, Abbreviated Environmental Assessment, and Environmental Assessment; actions requiring Environmental Impact Statements are prepared by US Department of Energy (US DOE). The relatively recent DOE initiative for agency-wide compliance with NEPA has created areas in which ORNL has found itself lacking adequate resources and expertise. These are discussed in this paper. Throughout ORNL, there is strong management support for compliance with NEPA which has resulted in enhanced awareness and implementation of the NEPA requirements. Guidance is being provided and Laboratory divisions are factoring early integration of NEPA into their project planning with the goal of ensuring that their activities are carried out in full compliance with the letter and the spirit of NEPA and the other environmental statutes and regulations

  14. Making NEPA more effective and economical for the new millennium

    Energy Technology Data Exchange (ETDEWEB)

    HANSEN,ROGER P.; WOLFF,THEODORE A.

    2000-03-08

    This paper focuses on a ten-element strategy for streamlining the NEPA process in order to achieve the Act's objectives while easing the considerable burden on agencies, the public, and the judicial system. In other words, this paper proposes a strategy for making NEPA work better and cost less. How these ten elements are timed and implemented is critical to any successful streamlining. The strategy elements discussed in this paper, in no particular order of priority, are as follows: (1) integrate the NEPA process with other environmental compliance and review procedures; (2) accelerate the decision time for determining the appropriate level of NEPA documentation; (3) conduct early and thorough internal EIS (or EA) scoping before public scoping or other public participation begins; (4) organize and implement public scoping processes that are more participatory than confrontational; (5) maintain an up-to-date compendium of environmental baseline information; (6) prepare more comprehensive, broad-scope umbrella EISs that can be used effectively for tiering; (7) encourage preparation of annotated outlines with detailed guidance that serve as a road map for preparation of each EIS or EA; (8) decrease the length and complexity of highly technical portions of NEPA documents; (9) increase and systematize NEPA compliance outreach, training, and organizational support; and (10) work diligently to influence the preparation of better organized, shorter, and more readable NEPA documents.

  15. 7 CFR 1794.11 - Apply NEPA early in the planning process.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Apply NEPA early in the planning process. 1794.11... National Environmental Policy Act § 1794.11 Apply NEPA early in the planning process. The environmental review process requires early coordination with and involvement of RUS. Applicants should consult...

  16. 40 CFR 1508.21 - NEPA process.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false NEPA process. 1508.21 Section 1508.21 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY TERMINOLOGY AND INDEX § 1508.21 NEPA process. NEPA process means all measures necessary for compliance with the requirements of section 2 and title I of NEPA....

  17. National Weatherization Assistance Program Characterization Describing the Recovery Act Period

    Energy Technology Data Exchange (ETDEWEB)

    Tonn, Bruce Edward [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Rose, Erin M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hawkins, Beth A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-10-01

    This report characterizes the U.S. Department of Energy s Weatherization Assistance Program (WAP) during the American Recovery and Reinvestment Act of 2009 (Recovery Act) period. This research was one component of the Recovery Act evaluation of WAP. The report presents the results of surveys administered to Grantees (i.e., state weatherization offices) and Subgrantees (i.e., local weatherization agencies). The report also documents the ramp up and ramp down of weatherization production and direct employment during the Recovery Act period and other challenges faced by the Grantees and Subgrantees during this period. Program operations during the Recovery Act (Program Year 2010) are compared to operations during the year previous to the Recovery Act (Program Year 2008).

  18. NEPA scoping averts agency funds from blowing in the wind: A NEPA success story

    Energy Technology Data Exchange (ETDEWEB)

    Wade, M.C.; Van Dyke, J. [Oak Ridge National Lab., TN (United States); Crew, J. [Agricultural Research Service, Wyndmoore, PA (United States)

    1998-06-01

    The National Environmental Policy Act (NEPA) process has been successful without the preparation of an Environmental Assessment (EA) or an Environmental Impact Statement (EIS) The Agricultural Research Service (ARS) has used early application of the NEPA process to make an informed decision and thus avoid negative ecological and financial results. The NEPA process was initiated to assess the potential impacts of constructing and operating a 6--9 megawatt wind turbine farm. The farm was to consist of up to 18 turbines to be placed along the spine of Plum Island which lies in the Atlantic Ocean off the shore of eastern Long Island. The rationale for the proposal was to provide an alternative energy source and thus avoid the expenditure of more than one million dollars per year on electricity and the dependency on the mainland public utility companies. A sufficient wind resource is readily available on Plum Island. Complicating the issue was a window of opportunity to obtain federal production tax credits if the wind energy system could become operational before July 1, 1999.

  19. NEPA scoping averts agency funds from blowing in the wind: A NEPA success story

    International Nuclear Information System (INIS)

    The National Environmental Policy Act (NEPA) process has been successful without the preparation of an Environmental Assessment (EA) or an Environmental Impact Statement (EIS) The Agricultural Research Service (ARS) has used early application of the NEPA process to make an informed decision and thus avoid negative ecological and financial results. The NEPA process was initiated to assess the potential impacts of constructing and operating a 6--9 megawatt wind turbine farm. The farm was to consist of up to 18 turbines to be placed along the spine of Plum Island which lies in the Atlantic Ocean off the shore of eastern Long Island. The rationale for the proposal was to provide an alternative energy source and thus avoid the expenditure of more than one million dollars per year on electricity and the dependency on the mainland public utility companies. A sufficient wind resource is readily available on Plum Island. Complicating the issue was a window of opportunity to obtain federal production tax credits if the wind energy system could become operational before July 1, 1999

  20. A NEPA compliance strategy plan for providing programmatic coverage to agency problems

    International Nuclear Information System (INIS)

    The National Environmental Policy Act (NEPA) of 1969, requires that all federal actions be reviewed before making a final decision to pursue a proposed action or one of its reasonable alternatives. The NEPA process is expected to begin early in the planning process. This paper discusses an approach for providing efficient and comprehensive NEPA coverage to large-scale programs. Particular emphasis has been given to determining bottlenecks and developing workarounds to such problems. Specifically, the strategy is designed to meet four specific goals: (1) provide comprehensive coverage, (2) reduce compliance cost/time, (3) prevent project delays, and (4) reduce document obsolescence

  1. D.C. Circuit broadly extends NEPA coverage for nuclear power plant accidents

    International Nuclear Information System (INIS)

    According to the D.C. Circuit Court of Appeals, the National Environmental Policy Act (NEPA) now requires complete evaluation of all aspects of human health affected by nuclear development, including psychological health. The Supreme Court may not agree with the circuit court's conclusion that the Nuclear Regulatory Commission must pay special attention to psychological health effects from nuclear accidents because this extension of NEPA may become a major new tool for slowing the development of nuclear energy production

  2. Streamlining the process: A strategy for making NEPA work better and cost less

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, R.P.; Hansen, J.D. [Hansen Environmental Consultants, Englewood, CO (United States); Wolff, T.A. [Sandia National Labs., Albuquerque, NM (United States)

    1998-05-01

    When the National Environmental Policy Act (NEPA) was enacted in 1969, neither Congress nor the Federal Agencies affected anticipated that implementation of the NEPA process would result in the intolerable delays, inefficiencies, duplication of effort, commitments of excessive financial and personnel resources, and bureaucratic gridlock that have become institutionalized. The 1975 Council on Environmental Quality (CEQ) regulations, which were intended to make the NEPA process more efficient and more useful to decision makers and the public, have either been largely ignored or unintentionally subverted. Agency policy mandates, like those of former Secretary of Energy Hazel R. O`Leary, to ``make NEPA work better and cost less`` have, so far, been disappointingly ineffectual. Federal Agencies have reached the point where almost every constituent of the NEPA process must be subjected to crisis management. This paper focuses on a ten-point strategy for streamlining the NEPA process in order to achieve the Act`s objectives while easing the considerable burden on agencies, the public, and the judicial system. How the ten points are timed and implemented is critical to any successful streamlining.

  3. Applying value engineering and modern assessment tools in managing NEPA: Improving effectiveness of the NEPA scoping and planning process

    Energy Technology Data Exchange (ETDEWEB)

    ECCLESTON, C.H.

    1998-09-03

    While the National Environmental Policy Act (NEPA) implementing regulations focus on describing ''What'' must be done, they provide surprisingly little direction on ''how'' such requirements are to be implemented. Specific implementation of these requirements has largely been left to the discretion of individual agencies. More than a quarter of a century after NEPA's enactment, few rigorous tools, techniques, or methodologies have been developed or widely adopted for implementing the regulatory requirements. In preparing an Environmental Impact Statement, agencies are required to conduct a public scoping process to determine the range of actions, alternatives, and impacts that will be investigated. Determining the proper scope of analysis is an element essential in the successful planning and implementation of future agency actions. Lack of rigorous tools and methodologies can lead to project delays, cost escalation, and increased risk that the scoping process may not adequately capture the scope of decisions that eventually might need to be considered. Recently, selected Value Engineering (VE) techniques were successfully used in managing a prescoping effort. A new strategy is advanced for conducting a pre-scoping/scoping effort that combines NEPA with VE. Consisting of five distinct phases, this approach has potentially wide-spread implications in the way NEPA, and scoping in particular, is practiced.

  4. National Environmental Policy Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Environmental Policy Act (NEPA) was the first major environmental law in the United States and established national environmental policies for the...

  5. 17 CFR 200.552 - NEPA planning.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false NEPA planning. 200.552 Section 200.552 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT... § 200.552 NEPA planning. Where it is reasonably foreseeable by the Commission that it may be required...

  6. Preliminary evaluation of DOE-NEPA monitoring system

    International Nuclear Information System (INIS)

    The objective of this analysis was to perform a preliminary investigation of the problems involved in designing a Department of Energy-National Environmental Policy Act (DOE-NEPA) compliance monitoring system. The requirement for such a system arose from the Council on Environmental Quality (CEQ-NEPA regulation effective July 30, 1979. The CEQ regulation uses the term monitoring to denote any method by which the lead agency can assure implementation of Environmental Impact Statement (EIS) and Record of Decision (ROD) environmental mitigation commitments. Monitoring is required for mitigation measures in important cases and may be carried out at agency discretion for all other cases. No definition of important is given in the regulation. The NEPA intent is that all environmental information and planning be incorporated into the decision process as early as possible. In keeping with this concept, any monitoring or enforcement program for a mitigation measure is expected to be adopted and briefly and concisely described in the ROD. Information is presented in four chapters entitled: federal and state compliance monitoring surveys; EIS information analysis; enforcement mechanisms; and administrative practice

  7. ARRA NEPA Quarterly Report- Second Report: DOL

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  8. ARRA NEPA Quarterly Report- Second Report: DOD

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  9. ARRA NEPA Quarterly Report- Second Report: DOT

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  10. ARRA NEPA Quarterly Report- First Report: DOE

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  11. The scientific challenges of NEPA: Future directions based on 20 years of experience

    International Nuclear Information System (INIS)

    January 1, 1990, marked the 20th anniversary of the signing of the National Environmental Policy Act (NEPA). Since this law was enacted, numerous institutions have assisted federal agencies in the implementation of NEPA, including the preparation of environmental impact statements and environmental assessments. The Ninth Oak Ridge National Laboratory Life Sciences Symposium was dedicated to the celebration of this anniversary. The symposium was held October 24--27, 1989, in Knoxville, Tennessee. The intent of the symposium was (1) to review what has been learned while performing NEPA assessments, (2) to summarize the state-of-the-art in methods and approaches, and (3) to define future opportunities and new approaches required to link high quality science to the decision-making process

  12. Tools for NEPA compliance: Baseline reports and compliance guides

    Energy Technology Data Exchange (ETDEWEB)

    Wolff, T.A. [Sandia National Labs., Albuquerque, NM (United States); Hansen, R.P. [Hansen Environmental Consultants, Englewood, CO (United States)

    1994-12-31

    Environmental baseline documents and NEPA compliance guides should be carried in every NEPA implementation ``tool kit``. These two indispensable tools can play a major role in avoiding repeated violations of NEPA requirements that have occurred over the past 26 years. This paper describes these tools, discusses their contents, and explains how they are used to prepare better NEPA documents more cost-effectively. Focus is on experience at Sandia Laboratories (NM).

  13. 36 CFR 1010.4 - NEPA Compliance Coordinator.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false NEPA Compliance Coordinator. 1010.4 Section 1010.4 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.4 NEPA Compliance Coordinator. (a) The NEPA Compliance Coordinator, as designated by the...

  14. 10 CFR 1021.103 - Adoption of CEQ NEPA regulations.

    Science.gov (United States)

    2010-01-01

    ... PROCEDURES General § 1021.103 Adoption of CEQ NEPA regulations. DOE adopts the regulations for implementing NEPA published by CEQ at 40 CFR parts 1500 through 1508. ... 10 Energy 4 2010-01-01 2010-01-01 false Adoption of CEQ NEPA regulations. 1021.103 Section...

  15. The Use of Recreation Planning Tools in U.S. Forest Service NEPA Assessments

    Science.gov (United States)

    Cerveny, Lee K.; Blahna, Dale J.; Stern, Marc J.; Mortimer, Michael J.; Predmore, S. Andrew; Freeman, James

    2011-09-01

    U.S. Forest Service managers are required to incorporate social and biophysical science information in planning and environmental analysis. The use of science is mandated by the National Environmental Policy Act, the National Forest Management Act, and U.S. Forest Service planning rules. Despite the agency's emphasis on `science-based' decision-making, little is known about how science is actually used in recreation planning and management. This study investigated the perceptions of Forest Service interdisciplinary (ID) team leaders for 106 NEPA projects dealing with recreation and travel management between 2005 and 2008. Our survey data show how managers rate the importance of social and biophysical science compared to other potential `success factors' in NEPA assessments. We also explore how team leaders value and use multi-disciplinary tools for recreation-related assessments. Results suggest that managers employ a variety of recreation planning tools in NEPA projects, but there appears to be no common understanding or approach for how or when these tools are incorporated. The Recreation Opportunity Spectrum (ROS) was the most frequently used planning tool, but the Visitor Experience and Resource Protection (VERP) framework was the most consistently valued tool by those who used it. We recommend further evaluation of the strengths and weaknesses of each planning tool and future development of procedures to select appropriate planning tools for use in recreation-related NEPA assessments.

  16. NEPA Source Guide for the Hanford Site. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Rued, W.J.

    1994-10-24

    This Source Guide will assist those working with the National Environmental Policy Act of 1969 (NEPA) to become more familiar with the Environmental Assessments (EA) and Environmental Impact Statements (EIS) that apply to specific activities and facilities at the Hanford Site. This document should help answer questions concerning NEPA coverage, history, processes, and the status of many of the buildings and units on and related to the Hanford Site. This document summarizes relevant EAs and EISs by briefly outlining the proposed action of each and the decision made by the US Department of Energy (DOE) or its predecessor agencies, the US Atomic Energy Commission (AEC), and the US Energy Research and Development Administration (ERDA), concerning the proposed action and current status of the buildings and units discussed in the proposed action. If a decision was officially stated by the DOE, as in a finding of no significant impact (FONSI) or a Record of Decision (ROD), and was located, a summary is provided in the text. Not all federal decisions, such as FONSIs and RODS, can be found in the Federal Register (FR). For example, although significant large-action FONSIs can be found in the FR, some low-interest FONSIs may have been published elsewhere.

  17. Visions of success and achievement in recreation-related USDA Forest Service NEPA processes

    International Nuclear Information System (INIS)

    The National Environmental Policy Act (NEPA) is incorporated into the planning and decision-making culture of all natural resource agencies in the U.S. Yet, we know little about how the attitudes and internal interactions of interdisciplinary (ID) teams engaged in NEPA processes influence process outcomes. We conducted a web-based survey of 106 ID team leaders involved with environmental analyses (EA) or environmental impact statements (EIS) for projects dealing with recreation and travel management on national forests. We explore how they define success in these processes and identify factors most powerfully associated with perceptions of positive outcomes. The survey revealed a tremendous diversity in definitions of success. Strong correlations between the perceived importance of particular indicators of success and their achievement suggest that pre-conceived notions may often help to shape process outcomes. Regression analyses revealed the following factors as the best predictors of ID team leaders' perception of an 'excellent outcome': achievement of the agency mission, whether compromise had taken place between the interested parties, team satisfaction and harmony, timely process completion, and project implementation. Yet, respondents consistently ranked compromise with interested parties and team member satisfaction among the least important measures of successful NEPA processes. Results suggest that clarifying appropriate measures of success in NEPA processes across the agency could make ID team performance more consistent. The research also suggests that greater attention to ID team interactions, both internally and between teams and interested publics, could result in better outcomes.

  18. Guidelines for compliance with the National Environmental Policy Act and the California Environmental Quality Act

    Energy Technology Data Exchange (ETDEWEB)

    Kielusiak, C.

    1993-02-01

    The National Environmental Policy Act of 1969 (NEPA) sets forth national policy for the protection of the environment. The NEPA process is intended to help officials of the federal government make decisions that are based on an understanding of environmental consequences, and take actions that protect, restore, and enhance the environment. The California Environmental Quality Act of 1970 (CEQA) is similar to NEPA. The California legislature established CEQA to inform both state and local governmental decision-makers and the public about potential significant environmental effects of proposed activities, to identify ways to avoid or reduce environmental impacts, and to disclose to the public the reasons why a project is approved if significant environmental effects are involved. Lawrence Berkeley Laboratory (LBL), complies with the provisions of both NEPA and CEQA. This document defines the responsibilities and authorities for NEPA/CEQA compliance at LBL.

  19. Guidelines for Hanford Site implementation of the National Environmental Policy Act

    Energy Technology Data Exchange (ETDEWEB)

    King, S.E.

    1989-03-01

    The National Environmental Policy Act (NEPA) environmental review process is mandatory for federal agencies. Understanding and complying with NEPA is extremely important to successfully planning and implementing programs at the Hanford Site. This report is intended to help planners and decision makers understand NEPA by describing the NEPA process as it is outlined in NEPA, in regulations, and in guidance information. The requirements and guidance documents that set forth the NEPA process are discussed. Some of the major NEPA concepts and issues are also addressed. This report is intended to be used as a general road map through the maze of NEPA requirements and guidance to ensure that Hanford Site activities are conducted in compliance with NEPA. Enhanced knowledge of the NEPA process is expected to increase the ability of the Hanford Site to work with regulators, interested parties and the public to ensure that the potential environmental impacts of DOE activities are fully considered at the Hanford Site. In addition, an enhanced understanding of NEPA will help project and program managers to integrate NEPA compliance requirements with program planning. 43 refs., 6 figs., 3 tabs.

  20. Public Involvement and the National Environmental Policy Act of 1969.

    Science.gov (United States)

    Fairfax, Sally K.

    The National Environmental Policy Act (NEPA) is based largely on assumptions about bureaucratic ineptitude as the cause of environmental degradation and citizen involvement as the cure. These assumptions and the procedural requirements of the NEPA process have severly undercut the limited contributions which citizen involvement can make to…

  1. 75 FR 3756 - The National Environmental Policy Act Procedures Manual

    Science.gov (United States)

    2010-01-22

    ... period for comments on the Draft NEPA Procedures Manual published in the Federal Register on December 4, 2009 (74 FR 63765, 74 FR 63787). DATES: The comment period for the Draft NEPA Procedures Manual is... National Indian Gaming Commission The National Environmental Policy Act Procedures Manual AGENCY:...

  2. NEPA source guide for the Hanford Site. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    Tifft, S.R.

    1995-09-27

    This Source Guide will assist those working with the National Environmental Policy Act of 1969 (NEPA) to become more familiar with the Environmental Assessments (EA) and Environmental Impact Statements (EIS) that apply to specific activities and facilities at the Hanford Site. This document should help answer questions concerning NEPA coverage, history, processes, and the status of many of the buildings and units on and related to the Hanford Site. This document summarizes relevant EAs and EISs by briefly outlining the proposed action of each and the decision made by the US Department of Energy (DOE) or its predecessor agencies, the US Atomic Energy Commission (AEC), and the US Energy Research and Development Administration (ERDA), concerning the proposed action and current status of the buildings and units discussed in the proposed action. If a decision was officially stated by the DOE, as in a Finding Of No Significant Impact (FONSI) or a Record of Decision (ROD), and was located, a summary is provided in the text. Not all federal decisions, such as FONSIs and RODS, can be found in the Federal Register (FR). For example, although significant large-action FONSIs can be found in the FR, some low-interest FONSIs may have been published elsewhere (i.e., local newspapers). The EA and EIS summaries are arranged in numerical order. To assist in locating a particular EA or EIS, the upper right comer of each page lists the number of the summary or summaries discussed on that page. Any draft EA or EIS is followed by a ``D.`` The EAs with nonstandard numbering schemes are located in Chapter 3.

  3. Advanced Burner Reactor Preliminary NEPA Data Study.

    Energy Technology Data Exchange (ETDEWEB)

    Briggs, L. L.; Cahalan, J. E.; Deitrich, L. W.; Fanning, T. H.; Grandy, C.; Kellogg, R.; Kim, T. K.; Yang, W. S.; Nuclear Engineering Division

    2007-10-15

    The Global Nuclear Energy Partnership (GNEP) is a new nuclear fuel cycle paradigm with the goals of expanding the use of nuclear power both domestically and internationally, addressing nuclear waste management concerns, and promoting nonproliferation. A key aspect of this program is fast reactor transmutation, in which transuranics recovered from light water reactor spent fuel are to be recycled to create fast reactor transmutation fuels. The benefits of these fuels are to be demonstrated in an Advanced Burner Reactor (ABR), which will provide a representative environment for recycle fuel testing, safety testing, and modern fast reactor design and safeguard features. Because the GNEP programs will require facilities which may have an impact upon the environment within the meaning of the National Environmental Policy Act of 1969 (NEPA), preparation of a Programmatic Environmental Impact Statement (PEIS) for GNEP is being undertaken by Tetra Tech, Inc. The PEIS will include a section on the ABR. In support of the PEIS, the Nuclear Engineering Division of Argonne National Laboratory has been asked to provide a description of the ABR alternative, including graphics, plus estimates of construction and operations data for an ABR plant. The compilation of this information is presented in the remainder of this report. Currently, DOE has started the process of engaging industry on the design of an Advanced Burner Reactor. Therefore, there is no specific, current, vendor-produced ABR design that could be used for this PEIS datacall package. In addition, candidate sites for the ABR vary widely as to available water, geography, etc. Therefore, ANL has based its estimates for construction and operations data largely on generalization of available information from existing plants and from the environmental report assembled for the Clinch River Breeder Reactor Plant (CRBRP) design [CRBRP, 1977]. The CRBRP environmental report was chosen as a resource because it thoroughly

  4. Proposed Columbia Wind Farm No. 1 : Draft Environmental Impact Statement, Joint NEPA/SEPA.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration; Klickitat County (Wash.)

    1995-03-01

    This Draft Environmental Impact Statement (DEIS) addresses the Columbia Wind Farm {number_sign}1 (Project) proposal for construction and operation of a 25 megawatt (MW) wind power project in the Columbia Hills area southeast of Goldendale in Klickitat County, Washington. The Project would be constructed on private land by Conservation and Renewable Energy System (CARES) (the Applicant). An Environmental Impact Statement is required under both NEPA and SEPA guidelines and is issued under Section 102 (2) (C) of the National Environmental Policy Act (NEPA) at 42 U.S.C. 4321 et seq and under the Washington State Environmental Policy Act (SEPA) as provided by RCW 43.21C.030 (2) (c). Bonneville Power Administration is the NEPA lead agency; Klickitat County is the nominal SEPA lead agency and CARES is the SEPA co-lead agency for this DEIS. The Project site is approximately 395 hectares (975 acres) in size. The Proposed Action would include approximately 91 model AWT-26 wind turbines. Under the No Action Alternative, the Project would not be constructed and existing grazing and agricultural activities on the site would continue.

  5. Proposed Columbia Wind Farm number-sign 1. Joint NEPA/SEPA draft environmental impact statement

    International Nuclear Information System (INIS)

    This Draft Environmental Impact Statement (DEIS) addresses the Columbia Wind Farm number-sign 1 (Project) proposal for construction and operation of a 25 megawatt (MW) wind power project in the Columbia Hills area southeast of Goldendale in Klickitat County, Washington. The Project would be constructed on private land by Conservation and Renewable Energy System (CARES) (the Applicant). An Environmental Impact Statement is required under both NEPA and SEPA guidelines and is issued under Section 102 (2) (C) of the National Environmental Policy Act (NEPA) at 42 U.S.C. 4321 et seq and under the Washington State Environmental Policy Act (SEPA) as provided by RCW 43.21C.030 (2) (c). Bonneville Power Administration is the NEPA lead agency; Klickitat County is the nominal SEPA lead agency and CARES is the SEPA co-lead agency for this DEIS. The Project site is approximately 395 hectares (975 acres) in size. The Proposed Action would include approximately 91 model AWT-26 wind turbines. Under the No Action Alternative, the Project would not be constructed and existing grazing and agricultural activities on the site would continue

  6. 21 CFR 25.10 - Policies and NEPA planning.

    Science.gov (United States)

    2010-04-01

    ... CFR 1502.25 and the HHS General Administration Manual, part 30: Environmental Protection. ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Policies and NEPA planning. 25.10 Section 25.10... ENVIRONMENTAL IMPACT CONSIDERATIONS General Provisions § 25.10 Policies and NEPA planning. (a) All...

  7. 32 CFR 651.27 - Programmatic NEPA analyses.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Programmatic NEPA analyses. 651.27 Section 651.27 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Records and Documents § 651.27 Programmatic NEPA...

  8. National Environmental Policy Act guidance: A model process

    International Nuclear Information System (INIS)

    The ''Model National Environmental Policy Act (NEPA) Process'' includes: References to regulations, guidance documents, and plans; training programs; procedures; and computer databases. Legislative Acts and reference documents from Congress, US Department of Energy, and Lockheed Idaho Technologies Company provide the bases for conducting NEPA at the Idaho National Engineering Laboratory (INEL). Lockheed Idaho Technologies Company (LITCO) NEPA / Permitting Department, the Contractor Environmental Organization (CEO) is responsible for developing and maintaining LITCO NEPA and permitting policies, guidance, and procedures. The CEO develops procedures to conduct environmental evaluations based on NEPA, Council on Environmental Quality (CEQ) regulations, and DOE guidance. This procedure includes preparation or support of environmental checklists, categorical exclusion determinations, environmental assessment determinations, environmental assessments, and environmental impact statements. In addition, the CEO uses this information to train personnel conducting environmental evaluations at the INEL. Streamlining these procedures fosters efficient use of resources, quality documents, and better decisions on proposed actions

  9. Successful NEPA compliance at the superconducting super collider laboratory: A case study

    International Nuclear Information System (INIS)

    In January, 1970, the President signed the National Environmental Policy Act (NEPA) into law. NEPA has become the basic policy-setting federal law relating to protection of the environment and has provided the initiative for passage of other federal and state environmental statutes. Although many of these statutes have unique requirements, there is a need to coordinate NEPA compliance with review requirements of the other environmental statutes in order to avoid delays that can be caused by proceeding separately under each statute. Because of its multi-purpose scope, the NEPA process is an excellent means for accomplishing the required coordination. The Director of the Superconducting Super Collider Laboratory has committed the Laboratory to Total Environmental Compliance. Environmental Compliance involves a dynamic set of factors-requiring system maintenance with integrated planning and control-that by design will identify requirements, ensure implementation of mitigative actions, track follow-on efforts, and plan for future requirements. The Record of Decision to proceed with the building of the SSC required that several mitigation actions be addressed. Identifying these requirements, their sources, and whether they can be addressed within the context of existing policies and procedures is required to ensure appropriate and timely mitigative actions. Applicable requirements may include federal, state, and local regulations, applicable Department of Energy Orders, best management practices, Laboratory requirements, and the adequacy and effectiveness of DOE and contractor management programs. Mitigative action is a principal aspect of total environmental compliance, conducted at all levels of the Laboratory, not just as an environmental function. Identified requirements are prioritized. Goals and objectives are set for implementing and successfully completing each mitigative action. Feedback mechanisms required for tracking the progress of each action are developed

  10. ARRA NEPA Quarterly Report- First Report: USDA ARS Report

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  11. ARRA NEPA Quarterly Report- First Report: DOT: FRA

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  12. ARRA NEPA Quarterly Report- Second Report: DOI: BoR

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  13. ARRA NEPA Quarterly Report- First Report: DOI: BoR

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  14. ARRA NEPA Quarterly Report- First Report: DOT: FAA

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  15. ARRA NEPA Quarterly Report- First Report: DHHS: HRSA

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  16. ARRA NEPA Quarterly Report- First Report: DHHS: ACF

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  17. ARRA NEPA Quarterly Report- Second Report: USDA ARS Report

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  18. ARRA NEPA Quarterly Report- First Report: USDA FAS Report

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  19. ARRA NEPA Quarterly Report- Second Report: USDA RD Report

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  20. ARRA NEPA Quarterly Report- First Report: USDA FSA Report

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  1. ARRA NEPA Quarterly Report- First Report: Dept. of Education

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  2. Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

    Science.gov (United States)

    Le Bihan, Amélie; Angulo-Barturen, Iñigo; Binkert, Christoph; Boss, Christoph; Brun, Reto; Brunner, Ralf; Buchmann, Stephan; Dechering, Koen J.; Delves, Michael; Ewerling, Sonja; Ferrer, Santiago; Fischli, Christoph; Gamo–Benito, Francisco Javier; Heidmann, Bibia; Jiménez-Díaz, María Belén; Leroy, Didier; Martínez, Maria Santos; Meyer, Solange; Moehrle, Joerg J.; Noviyanti, Rintis; Sanz, Laura María; Sauerwein, Robert W.; Scheurer, Christian; Schleiferboeck, Sarah; Sinden, Robert; Snyder, Christopher; Straimer, Judith; Wirjanata, Grennady; Marfurt, Jutta; Weller, Thomas; Clozel, Martine; Wittlin, Sergio

    2016-01-01

    Background Artemisinin resistance observed in Southeast Asia threatens the continued use of artemisinin-based combination therapy in endemic countries. Additionally, the diversity of chemical mode of action in the global portfolio of marketed antimalarials is extremely limited. Addressing the urgent need for the development of new antimalarials, a chemical class of potent antimalarial compounds with a novel mode of action was recently identified. Herein, the preclinical characterization of one of these compounds, ACT-451840, conducted in partnership with academic and industrial groups is presented. Method and Findings The properties of ACT-451840 are described, including its spectrum of activities against multiple life cycle stages of the human malaria parasite Plasmodium falciparum (asexual and sexual) and Plasmodium vivax (asexual) as well as oral in vivo efficacies in two murine malaria models that permit infection with the human and the rodent parasites P. falciparum and Plasmodium berghei, respectively. In vitro, ACT-451840 showed a 50% inhibition concentration of 0.4 nM (standard deviation [SD]: ± 0.0 nM) against the drug-sensitive P. falciparum NF54 strain. The 90% effective doses in the in vivo efficacy models were 3.7 mg/kg against P. falciparum (95% confidence interval: 3.3–4.9 mg/kg) and 13 mg/kg against P. berghei (95% confidence interval: 11–16 mg/kg). ACT-451840 potently prevented male gamete formation from the gametocyte stage with a 50% inhibition concentration of 5.89 nM (SD: ± 1.80 nM) and dose-dependently blocked oocyst development in the mosquito with a 50% inhibitory concentration of 30 nM (range: 23–39). The compound’s preclinical safety profile is presented and is in line with the published results of the first-in-man study in healthy male participants, in whom ACT-451840 was well tolerated. Pharmacokinetic/pharmacodynamic (PK/PD) modeling was applied using efficacy in the murine models (defined either as antimalarial activity or as

  3. The complete mitochondrial genome of Nepa hoffmanni (Hemiptera: Heteroptera: Nepidae).

    Science.gov (United States)

    Zhang, Danli; Xie, Tongyin; Li, Teng; Bu, Wenjun

    2016-09-01

    The complete mitochondrial genome (mt-genome) of Nepa hoffmanni has been reported in this study. This mitochondrial genome is 15 774 bp long, with an A + T content of 72.04%, containing the typical 37 genes (13 protein-coding genes (PCGs), 22 transfer RNA genes, and two ribosomal RNA genes) and a control region. All genes are arranged in the same gene order as most other known heteropteran mt-genome. This is the second completely sequenced mt-genome from the family Nepidae of Nepomorpha. Bayesian analyses were performed using the mt-genome of Nepa hoffmanni and its relatives, including 17 taxa, showing a reasonable placement of Nepa hoffmanni. PMID:26403708

  4. 43 CFR 36.6 - NEPA compliance and lead agency.

    Science.gov (United States)

    2010-10-01

    ... the costs. (2) The reasonable administrative and other costs of EIS preparation shall be reimbursed by... lead agency. (a) The provisions of NEPA and the Council for Environmental Quality regulations (40 CFR... EIS and publish a notice of its availability in the Federal Register. (c) Cost reimbursement. (1)...

  5. 32 CFR 651.6 - NEPA analysis staffing.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true NEPA analysis staffing. 651.6 Section 651.6 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY... depth of analysis required. In cases where the document addresses impacts to an environment...

  6. From the office to the field: areas of tension and consensus in the implementation of the National Environmental Policy Act within the US Forest Service.

    Science.gov (United States)

    Stern, Marc J; Predmore, S Andrew; Mortimer, Michael J; Seesholtz, David N

    2010-06-01

    We conducted an online survey (n = 3321) followed by five focus groups with Forest Service employees involved in compliance with the National Environmental Policy Act (NEPA) to explore agency views of how NEPA should be implemented within the agency. We filter these perceptions through the lenses of different functional groups within the agency, each with its own role in agency compliance with NEPA and its own suite of perceived accountabilities. In doing so, we uncover areas of consensus regarding valued practices as well as tensions between employees with different roles in NEPA compliance. General consensus exists regarding the importance of the effective functioning of interdisciplinary teams, but opinions about what constitutes an effective team vary. Findings suggest that NEPA serves as a playing field for competing accountabilities felt by line officers, disciplinary specialists, and advisory personnel within the agency, as each attempts to exert influence over NEPA processes and their outcomes. PMID:20223584

  7. Experimental characterization of a small custom-built double-acting gamma-type stirling engine

    Science.gov (United States)

    Intsiful, Peter; Mensah, Francis; Thorpe, Arthur

    This paper investigates characterization of a small custom-built double-acting gamma-type stirling engine. Stirling-cycle engine is a reciprocating energy conversion machine with working spaces operating under conditions of oscillating pressure and flow. These conditions may be due to compressibility as wells as pressure and temperature fluctuations. In standard literature, research indicates that there is lack of basic physics to account for the transport phenomena that manifest themselves in the working spaces of reciprocating engines. Previous techniques involve governing equations: mass, momentum and energy. Some authors use engineering thermodynamics. None of these approaches addresses this particular engine. A technique for observing and analyzing the behavior of this engine via parametric spectral profiles has been developed, using laser beams. These profiles enabled the generation of pv-curves and other trajectories for investigating the thermos-physical and thermos-hydrodynamic phenomena that manifest in the exchangers. The engine's performance was examined. The results indicate that with current load of 35.78A, electric power of 0.505 kW was generated at a speed of 240 rpm and 29.50 percent efficiency was obtained. Nasa grants to Howard University NASA/HBCU-NHRETU & CSTEA.

  8. Identification and characterization of a dual-acting antinematodal agent against the pinewood nematode, Bursaphelenchus xylophilus.

    Directory of Open Access Journals (Sweden)

    Wan-Suk Oh

    Full Text Available The pinewood nematode (PWN, Bursaphelenchus xylophilus, is a mycophagous and phytophagous pathogen responsible for the current widespread epidemic of the pine wilt disease, which has become a major threat to pine forests throughout the world. Despite the availability of several preventive trunk-injection agents, no therapeutic trunk-injection agent for eradication of PWN currently exists. In the characterization of basic physiological properties of B. xylophilus YB-1 isolates, we established a high-throughput screening (HTS method that identifies potential hits within approximately 7 h. Using this HTS method, we screened 206 compounds with known activities, mostly antifungal, for antinematodal activities and identified HWY-4213 (1-n-undecyl-2-[2-fluorphenyl] methyl-3,4-dihydro-6,7-dimethoxy-isoquinolinium chloride, a highly water-soluble protoberberine derivative, as a potent nematicidal and antifungal agent. When tested on 4 year-old pinewood seedlings that were infected with YB-1 isolates, HWY-4213 exhibited a potent therapeutic nematicidal activity. Further tests of screening 39 Caenorhabditis elegans mutants deficient in channel proteins and B. xylophilus sensitivity to Ca(2+ channel blockers suggested that HWY-4213 targets the calcium channel proteins. Our study marks a technical breakthrough by developing a novel HTS method that leads to the discovery HWY-4213 as a dual-acting antinematodal and antifungal compound.

  9. National Environmental Policy Act compliance guide. Volume II (reference book)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-09-01

    This document (Volume II of the National Environmental Policy Act Compliance Guide) contains current copies of regulations and guidance from the Council on Environmental Quality, the Department of Energy, the Department of State, and the Environmental Protection Agency, related to compliance with the National Environmental Policy Act of 1969 (NEPA).

  10. A model for determining when an analysis contains sufficient detail to provide adequate NEPA coverage for a proposed action

    International Nuclear Information System (INIS)

    Neither the National Environmental Policy Act (NEPA) nor its subsequent regulations provide substantive guidance for determining the Level of detail, discussion, and analysis that is sufficient to adequately cover a proposed action. Yet, decisionmakers are routinely confronted with the problem of making such determinations. Experience has shown that no two decisionmakers are Likely to completely agree on the amount of discussion that is sufficient to adequately cover a proposed action. one decisionmaker may determine that a certain Level of analysis is adequate, while another may conclude the exact opposite. Achieving a consensus within the agency and among the public can be problematic. Lacking definitive guidance, decisionmakers and critics alike may point to a universe of potential factors as the basis for defending their claim that an action is or is not adequately covered. Experience indicates that assertions are often based on ambiguous opinions that can be neither proved nor disproved. Lack of definitive guidance slows the decisionmaking process and can result in project delays. Furthermore, it can also Lead to inconsistencies in decisionmaking, inappropriate Levels of NEPA documentation, and increased risk of a project being challenged for inadequate coverage. A more systematic and less subjective approach for making such determinations is obviously needed. A paradigm for reducing the degree of subjectivity inherent in such decisions is presented in the following paper. The model is specifically designed to expedite the decisionmaking process by providing a systematic approach for making these determination. In many cases, agencies may find that using this model can reduce the analysis and size of NEPA documents

  11. 36 CFR 1010.16 - Actions to encourage agency cooperation early in the NEPA process.

    Science.gov (United States)

    2010-07-01

    ... cooperation early in the NEPA process. 1010.16 Section 1010.16 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.16 Actions to encourage agency cooperation early in the NEPA process. Consistent with 40 CFR 1501.6, the Trust may request the NPS to be a cooperating agency for actions...

  12. 40 CFR 1501.2 - Apply NEPA early in the process.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Apply NEPA early in the process. 1501.2 Section 1501.2 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY NEPA AND AGENCY PLANNING... insure the integrated use of the natural and social sciences and the environmental design arts...

  13. CHARACTERIZATION OF EXPOSURES TO WORKERS COVERED UNDER THE U.S. ENERGY EMPLOYEES COMPENSATION ACT

    OpenAIRE

    Neton, James W.

    2014-01-01

    Since the mid-1940s, hundreds of thousands of workers have been engaged in nuclear weapons-related activities for the U.S. Department of Energy (DOE) and its predecessor agencies. In 2000, Congress promulgated the Energy Employees Occupational Illness Compensation Program Act of 2000 (EEOICPA), which provides monetary compensation and medical benefits to certain energy employees who have developed cancer. Under Part B of EEOICPA, the National Institute for Occupational Safety and Health (NIOS...

  14. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act: Volume 7

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-01-01

    The Yucca Mountain site in Neavada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended and approved for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in accordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package;and to present the plans for obtaining hte geologic information necessary to demonstrate the suitability of the site for a repository, to design the repository and the waste package, to prepare and environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and developing a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing principles, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed.

  15. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act: Volume 6

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-01-01

    The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in accordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package;and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and developing a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing principles, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed.

  16. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act: Volume 7

    International Nuclear Information System (INIS)

    The Yucca Mountain site in Neavada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended and approved for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in accordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package;and to present the plans for obtaining hte geologic information necessary to demonstrate the suitability of the site for a repository, to design the repository and the waste package, to prepare and environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and developing a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing principles, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed

  17. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act: Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-01-01

    The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in acordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for a repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and eveloping a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing prinicples, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed. 880 refs., 130 figs., 25 tabs.

  18. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act: Volume 4

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-01-01

    The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended and approved by the President for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in accordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site; to describe the conceptual designs for the repository and the waste package; and to present the plans for obtaining the geologic information necessary to demonstate the suitability of the site for a repository, to desin the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and developing a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next; it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing principles, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed.

  19. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act

    International Nuclear Information System (INIS)

    The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended by the Secretary of Energy and approved by the President for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared by the US Department of Energy (DOE) in accordance with the requirements of the Nulcear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package;and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for a repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and developing a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing principles, and organization of the site characterization plan are oulined, and compliance with applicable regulations is discussed

  20. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-01-01

    The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended by the Secretary of Energy and approved by the President for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared by the US Department of Energy (DOE) in accordance with the requirements of the Nulcear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package;and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for a repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and developing a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing principles, and organization of the site characterization plan are oulined, and compliance with applicable regulations is discussed.

  1. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act: Volume 4

    International Nuclear Information System (INIS)

    The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended and approved by the President for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in accordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site; to describe the conceptual designs for the repository and the waste package; and to present the plans for obtaining the geologic information necessary to demonstate the suitability of the site for a repository, to desin the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and developing a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next; it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing principles, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed

  2. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act: Volume 2

    International Nuclear Information System (INIS)

    The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in accordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site; to describe the conceptual designs for the repository and the waste package and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for a repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. Chapter 3 summarizes present knowledge of the regional and site hydrologic systems. The purpose of the information presented is to (1) describe the hydrology based on available literature and preliminary site-exploration activities that have been or are being performed and (2) provide information to be used to develop the hydrologic aspects of the planned site characterization program. Chapter 4 contains geochemical information about the Yucca Mountain site. The chapter references plan for continued collection of geochemical data as a part of the site characterization program. Chapter 4 describes and evaluates data on the existing climate and site meterology, and outlines the suggested procedures to be used in developing and validating methods to predict future climatic variation. 534 refs., 100 figs., 72 tabs

  3. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act: Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-01-01

    The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in accordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site; to describe the conceptual designs for the repository and the waste package and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for a repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. Chapter 3 summarizes present knowledge of the regional and site hydrologic systems. The purpose of the information presented is to (1) describe the hydrology based on available literature and preliminary site-exploration activities that have been or are being performed and (2) provide information to be used to develop the hydrologic aspects of the planned site characterization program. Chapter 4 contains geochemical information about the Yucca Mountain site. The chapter references plan for continued collection of geochemical data as a part of the site characterization program. Chapter 4 describes and evaluates data on the existing climate and site meterology, and outlines the suggested procedures to be used in developing and validating methods to predict future climatic variation. 534 refs., 100 figs., 72 tabs.

  4. Discovery and Characterization of ACT-451840: an Antimalarial Drug with a Novel Mechanism of Action.

    Science.gov (United States)

    Boss, Christoph; Aissaoui, Hamed; Amaral, Nathalie; Bauer, Aude; Bazire, Stephanie; Binkert, Christoph; Brun, Reto; Bürki, Cédric; Ciana, Claire-Lise; Corminboeuf, Olivier; Delahaye, Stephane; Dollinger, Claire; Fischli, Christoph; Fischli, Walter; Flock, Alexandre; Frantz, Marie-Céline; Girault, Malory; Grisostomi, Corinna; Friedli, Astrid; Heidmann, Bibia; Hinder, Claire; Jacob, Gael; Le Bihan, Amelie; Malrieu, Sophie; Mamzed, Saskia; Merot, Aurelien; Meyer, Solange; Peixoto, Sabrina; Petit, Nolwenn; Siegrist, Romain; Trollux, Julien; Weller, Thomas; Wittlin, Sergio

    2016-09-20

    More than 40 % of the world's population is at risk of being infected with malaria. Most malaria cases occur in the countries of sub-Saharan Africa, Central and South America, and Asia. Resistance to standard therapy, including artemisinin combinations, is increasing. There is an urgent need for novel antimalarials with new mechanisms of action. In a phenotypic screen, we identified a series of phenylalanine-based compounds that exhibit antimalarial activity via a new and yet unknown mechanism of action. Our optimization efforts culminated in the selection of ACT-451840 [(S,E)-N-(4-(4-acetylpiperazin-1-yl)benzyl)-3-(4-(tert-butyl)phenyl)-N-(1-(4-(4-cyanobenzyl)piperazin-1-yl)-1-oxo-3-phenylpropan-2-yl)acrylamide] for clinical development. Herein we describe our optimization efforts from the screening hit to the potential drug candidate with respect to antiparasitic activity, drug metabolism and pharmacokinetics (DMPK) properties, and in vivo pharmacological efficacy.

  5. Experimental characterization of Cis-acting elements important for translation and transcription in halophilic archaea.

    Directory of Open Access Journals (Sweden)

    Mariam Brenneis

    2007-12-01

    Full Text Available The basal transcription apparatus of archaea is well characterized. However, much less is known about the mechanisms of transcription termination and translation initation. Recently, experimental determination of the 5'-ends of ten transcripts from Pyrobaculum aerophilum revealed that these are devoid of a 5'-UTR. Bioinformatic analysis indicated that many transcripts of other archaeal species might also be leaderless. The 5'-ends and 3'-ends of 40 transcripts of two haloarchaeal species, Halobacterium salinarum and Haloferax volcanii, have been determined. They were used to characterize the lengths of 5'-UTRs and 3'-UTRs and to deduce consensus sequence-elements for transcription and translation. The experimental approach was complemented with a bioinformatics analysis of the H. salinarum genome sequence. Furthermore, the influence of selected 5'-UTRs and 3'-UTRs on transcript stability and translational efficiency in vivo was characterized using a newly established reporter gene system, gene fusions, and real-time PCR. Consensus sequences for basal promoter elements could be refined and a novel element was discovered. A consensus motif probably important for transcriptional termination was established. All 40 haloarchaeal transcripts analyzed had a 3'-UTR (average size 57 nt, and their 3'-ends were not posttranscriptionally modified. Experimental data and genome analyses revealed that the majority of haloarchaeal transcripts are leaderless, indicating that this is the predominant mode for translation initiation in haloarchaea. Surprisingly, the 5'-UTRs of most leadered transcripts did not contain a Shine-Dalgarno (SD sequence. A genome analysis indicated that less than 10% of all genes are preceded by a SD sequence and even most proximal genes in operons lack a SD sequence. Seven different leadered transcripts devoid of a SD sequence were efficiently translated in vivo, including artificial 5'-UTRs of random sequences. Thus, an interaction of

  6. Characterization of inhibitors acting at the synthetase site of Escherichia coli asparagine synthetase B.

    Science.gov (United States)

    Boehlein, S K; Nakatsu, T; Hiratake, J; Thirumoorthy, R; Stewart, J D; Richards, N G; Schuster, S M

    2001-09-18

    Asparagine synthetase catalyzes the ATP-dependent formation of L-asparagine from L-aspartate and L-glutamine, via a beta-aspartyl-AMP intermediate. Since interfering with this enzyme activity might be useful for treating leukemia and solid tumors, we have sought small-molecule inhibitors of Escherichia coli asparagine synthetase B (AS-B) as a model system for the human enzyme. Prior work showed that L-cysteine sulfinic acid competitively inhibits this enzyme by interfering with L-aspartate binding. Here, we demonstrate that cysteine sulfinic acid is also a partial substrate for E. coli asparagine synthetase, acting as a nucleophile to form the sulfur analogue of beta-aspartyl-AMP, which is subsequently hydrolyzed back to cysteine sulfinic acid and AMP in a futile cycle. While cysteine sulfinic acid did not itself constitute a clinically useful inhibitor of asparagine synthetase B, these results suggested that replacing this linkage by a more stable analogue might lead to a more potent inhibitor. A sulfoximine reported recently by Koizumi et al. as a competitive inhibitor of the ammonia-dependent E. coli asparagine synthetase A (AS-A) [Koizumi, M., Hiratake, J., Nakatsu, T., Kato, H., and Oda, J. (1999) J. Am. Chem. Soc. 121, 5799-5800] can be regarded as such a species. We found that this sulfoximine also inhibited AS-B, effectively irreversibly. Unlike either the cysteine sulfinic acid interaction with AS-B or the sulfoximine interaction with AS-A, only AS-B productively engaged in asparagine synthesis could be inactivated by the sulfoximine; free enzyme was unaffected even after extended incubation with the sulfoximine. Taken together, these results support the notion that sulfur-containing analogues of aspartate can serve as platforms for developing useful inhibitors of AS-B. PMID:11551215

  7. ARRA NEPA Quarterly Report- First Report: USDA Office of Operations Report

    Data.gov (United States)

    Council on Environmental Quality, Executive Office of the President — Reports prepared by the Departments and Agencies on status of NEPA progress for activities and projects funded under Division A of the American Recovery and...

  8. Synthesis of facilitation, communication, information, and technology to enhance public involvement through the Transportation Resource Exchange Center (T-REX) web site in accordance with the NEPA planning and decision-making process: a best practice

    OpenAIRE

    Espinosa, Judith M; White, Mary E

    2001-01-01

    The Transportation Resource Exchange Center (T-REX) is a first-of-its-kind Virtual Library dedicated to providing information about the transportation of radioactive materials to stakeholders. Guided by the principles of the National Environmental Policy Act (NEPA) planning and decision-making process, the Web site was created to serve as a “one-stop shop,” neutral source for information, to facilitate public involvement, overcome information gaps, and foster clearer communication and underst...

  9. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act

    International Nuclear Information System (INIS)

    Chapter six describes the basis for facility design, the completed facility conceptual design, the completed analytical work relating to the resolution of design issues, and future design-related work. The basis for design and the conceptual design information presented in this chapter meet the requiremenrs of the Nuclear Waste Policy Act of 1982, for a conceptual repository design that takes into account site-specific requirements. This information is presented to permit a critical evaluation of planned site characterization activities. Chapter seven describes waste package components, emplacement environment, design, and status of research and development that support the Nevada Nuclear Waste Storage Investigation (NNWSI) Project. The site characterization plan (SCP) discussion of waste package components is contained entirely within this chapter. The discussion of emplacement environment in this chapter is limited to considerations of the environment that influence, or which may influence, if perturbed, the waste packages and their performance (particularly hydrogeology, geochemistry, and borehole stability). The basis for conceptual waste package design as well as a description of the design is included in this chapter. The complete design will be reported in the advanced conceptual design (ACD) report and is not duplicated in the SCP. 367 refs., 173 figs., 68 tabs

  10. Site characterization plan: Yucca Mountain site, Nevada research and development area, Nevada: Consultation draft, Nuclear Waste Policy Act

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-01-01

    Chapter six describes the basis for facility design, the completed facility conceptual design, the completed analytical work relating to the resolution of design issues, and future design-related work. The basis for design and the conceptual design information presented in this chapter meet the requirements of the Nuclear Waste Policy Act of 1982, for a conceptual repository design that takes into account site-specific requirements. This information is presented to permit a critical evaluation of planned site characterization activities. Chapter seven describes waste package components, emplacement environment, design, and status of research and development that support the Nevada Nuclear Waste Storage Investigation (NNWSI) Project. The site characterization plan (SCP) discussion of waste package components is contained entirely within this chapter. The discussion of emplacement environment in this chapter is limited to considerations of the environment that influence, or which may influence, if perturbed, the waste packages and their performance (particularly hydrogeology, geochemistry, and borehole stability). The basis for conceptual waste package design as well as a description of the design is included in this chapter. The complete design will be reported in the advanced conceptual design (ACD) report and is not duplicated in the SCP. 367 refs., 173 figs., 68 tabs.

  11. 7 CFR 1940.310 - Categorical exclusions from National Environmental Policy Act (NEPA) reviews.

    Science.gov (United States)

    2010-01-01

    ..., with no expansion in the number of units; (4) Self-Help Technical Assistance Grants; *(5) The approval... lots or expansion for which approval is being requested; (9) The purchase of any existing, non-FmHA or... forestry management and marketing plan; and (11) Financial assistance for the conversion of no more...

  12. National Environmental Policy Act (NEPA) Source Guide for the Hanford Site September 1999

    Energy Technology Data Exchange (ETDEWEB)

    CUMMINS, G.D.

    1999-09-01

    This document summarizes relevant EAs and EISs by briefly outlining the proposed action of each document and the decision made by the U.S. Department of Energy (DOE) or its predecessor agencies, the U.S. Atomic Energy Commission (AEC) and the US. Energy Research and Development Administration (ERDA). The summary includes the proposed action alternatives and current status of the proposed action. If a decision officially was stated by the DOE, as in a finding of no significant impact (FONSI) or a record of decision (ROD), and the decision was located, a summary is provided. Not all federal decisions, such as FONSIs and RODs, can be found in the Federal Register (FR). For example, although significant large-action FONSIs can be found in the FR, some low-interest FONSIs might have been published elsewhere (i.e., local newspapers).

  13. Site characterization progress report: Yucca Mountain, Nevada, April 1, 1990--September 30, 1990, Number 3; Nuclear Waste Policy Act (Section 113)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-03-01

    In accordance with the requirements of Section 113(b)(3) of the Nuclear Waste Policy Act of 1982 (NWPA), as amended, the US Department of Energy has prepared this report on the progress of site characterization activities at Yucca Mountain, Nevada, for the period April 1 through September 30, 1990. This report is the third of a series of reports that are issued at intervals of approximately six months during site characterization. The report covers a number of new initiatives to improve the effectiveness of the site characterization program and covers continued efforts related to preparatory activities, study plans, and performance assessment. 85 refs., 2 figs., 3 tabs.

  14. 75 FR 29996 - Review of MMS NEPA Policies, Practices, and Procedures for OCS Oil and Gas Exploration and...

    Science.gov (United States)

    2010-05-28

    ... (OCS) oil and gas exploration and development. This review of MMS NEPA policies, practices and procedures is being conducted as a result of the oil spill from the Deepwater Horizon well and drilling rig... QUALITY Review of MMS NEPA Policies, Practices, and Procedures for OCS Oil and Gas Exploration...

  15. Hanford Site implementation of the National Environmental Policy Act: Activities tracking

    Energy Technology Data Exchange (ETDEWEB)

    Killinger, M.H.; Selby, K.B.

    1989-06-01

    The National Environmental Policy Act (NEPA) environmental review process is mandatory for federal agencies. This report provides the DOE Richland Operations Office (DOE-RL) and the Hanford contractors with a method for tracking, integrating, and coordinating NEPA compliance activities at the Hanford Site. The environmental review process is briefly described and illustrated in a flow chart. The report then explains a method for developing project timecharts that show when documents or decision points were completed or are projected to be completed. The tracking system has been automated and placed on the Hanford Local Area Network (HLAN). Time schedules for many Hanford projects are available for viewing. 4 refs., 6 figs.

  16. Synthesis and characterization of Pi4, a scorpion toxin from Pandinus imperator that acts on K+ channels.

    Science.gov (United States)

    M'Barek, Sarrah; Mosbah, Amor; Sandoz, Guillaume; Fajloun, Ziad; Olamendi-Portugal, Timoteo; Rochat, Hervé; Sampieri, François; Guijarro, J Iñaki; Mansuelle, Pascal; Delepierre, Muriel; De Waard, Michel; Sabatier, Jean-Marc

    2003-09-01

    Pi4 is a 38-residue toxin cross-linked by four disulfide bridges that has been isolated from the venom of the Chactidae scorpion Pandinus imperator. Together with maurotoxin, Pi1, Pi7 and HsTx1, Pi4 belongs to the alpha KTX6 subfamily of short four-disulfide-bridged scorpion toxins acting on K+ channels. Due to its very low abundance in venom, Pi4 was chemically synthesized in order to better characterize its pharmacology and structural properties. An enzyme-based cleavage of synthetic Pi4 (sPi4) indicated half-cystine pairings between Cys6-Cys27, Cys12-32, Cys16-34 and Cys22-37, which denotes a conventional pattern of scorpion toxin reticulation (Pi1/HsTx1 type). In vivo, sPi4 was lethal after intracerebroventricular injection to mice (LD50 of 0.2 microg per mouse). In vitro, addition of sPi4 onto Xenopus laevis oocytes heterologously expressing various voltage-gated K+ channel subtypes showed potent inhibition of currents from rat Kv1.2 (IC50 of 8 pm) and Shaker B (IC50 of 3 nm) channels, whereas no effect was observed on rat Kv1.1 and Kv1.3 channels. The sPi4 was also found to compete with 125I-labeled apamin for binding to small-conductance Ca(2+)-activated K+ (SK) channels from rat brain synaptosomes (IC50 value of 0.5 microm). sPi4 is a high affinity blocker of the Kv1.2 channel. The toxin was docked (BIGGER program) on the Kv channel using the solution structure of sPi4 and a molecular model of the Kv1.2 channel pore region. The model suggests a key role for residues Arg10, Arg19, Lys26 (dyad), Ile28, Lys30, Lys33 and Tyr35 (dyad) in the interaction and the associated blockage of the Kv1.2 channel.

  17. Pacific Northwest National Laboratory National Environmental Policy Act Compliance Program -- FY 2010 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Weeks, Regan S.

    2011-04-20

    During fiscal year (FY) 2010, Pacific Northwest National Laboratory (PNNL) Environmental Protection and Regulatory Programs Division (before March 1, 2011 known as the Environmental Management Services Department) staff performed a number of activities as part of PNNL’s National Environmental Policy Act (NEPA) compliance program. These activities helped to verify U.S. Department of Energy (DOE) Pacific Northwest Site Office (PNSO) and Richland Operations Office (RL) compliance with NEPA requirements and streamline the NEPA process for federal activities conducted at PNNL. Self-assessments were performed to address NEPA compliance and cultural and biological resource protection. The NEPA self-assessments focused on implementation within the PNNL Energy and Environment Directorate and routine maintenance activities conducted during the previous calendar year. The cultural and biological resource self-assessments were conducted in accordance with the PNSO Cultural and Biological Resources Management Plan, which specifies annual monitoring of important resources to assess and document the status of the resources and the associated protective mechanisms in place to protect sensitive resources.

  18. 43 CFR 46.160 - Limitations on actions during the NEPA analysis process.

    Science.gov (United States)

    2010-10-01

    ... analysis process. 46.160 Section 46.160 Public Lands: Interior Office of the Secretary of the Interior... Quality § 46.160 Limitations on actions during the NEPA analysis process. During the preparation of a... accordance with 40 CFR 1506.1 when that action is within the scope of, and analyzed in, an existing...

  19. 10 CFR 1021.330 - Programmatic (including site-wide) NEPA documents.

    Science.gov (United States)

    2010-01-01

    ... documents. (a) When required to support a DOE programmatic decision (40 CFR 1508.18(b)(3)), DOE shall prepare a programmatic EIS or EA (40 CFR 1502.4). DOE may also prepare a programmatic EIS or EA at any... 10 Energy 4 2010-01-01 2010-01-01 false Programmatic (including site-wide) NEPA documents....

  20. 33 CFR 385.14 - Incorporation of NEPA and related considerations into the implementation process.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Incorporation of NEPA and related considerations into the implementation process. 385.14 Section 385.14 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE...

  1. Consultation draft: Site characterization plan overview, Deaf Smith County Site, Texas: Nuclear Waste Policy Act (Section 113)

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    The Department of Energy (DOE) is preparing a site characterization plan for the candidate site in Deaf Smith County, Texas. The DOE has provided, for information and review, a consultation draft of the plan to the State of Texas and the US Nuclear Regulatory Commission. The site characterization plan is a lengthy document that describes in considerable detail the program that will be conducted to characterize the geologic, hydrologic, and other conditions relevant to the suitability of the site for a repository. The overview presented here consists of brief summaries of important topics covered in the consultation draft of the site characterization plan; it is not a substitute for the site characterization plan. The arrangement of the overview is similar to that of the plan itself, with brief descriptions of the repository system - the site, the repository, and the waste package - preceding the discussion of the characterization program to be carried out at the Deaf Smith County site. It is intended primarily for the management staff of organizations involved in the DOE's repository program or other persons who might wish to understand the general scope of the site-characterization program, the activities to be conducted, and the facilities to be constructed rather than the technical details of site characterization. 15 figs., 1 tab.

  2. Consultation draft: Site characterization plan overview, Deaf Smith County Site, Texas: Nuclear Waste Policy Act (Section 113)

    International Nuclear Information System (INIS)

    The Department of Energy (DOE) is preparing a site characterization plan for the candidate site in Deaf Smith County, Texas. The DOE has provided, for information and review, a consultation draft of the plan to the State of Texas and the US Nuclear Regulatory Commission. The site characterization plan is a lengthy document that describes in considerable detail the program that will be conducted to characterize the geologic, hydrologic, and other conditions relevant to the suitability of the site for a repository. The overview presented here consists of brief summaries of important topics covered in the consultation draft of the site characterization plan; it is not a substitute for the site characterization plan. The arrangement of the overview is similar to that of the plan itself, with brief descriptions of the repository system - the site, the repository, and the waste package - preceding the discussion of the characterization program to be carried out at the Deaf Smith County site. It is intended primarily for the management staff of organizations involved in the DOE's repository program or other persons who might wish to understand the general scope of the site-characterization program, the activities to be conducted, and the facilities to be constructed rather than the technical details of site characterization. 15 figs., 1 tab

  3. Discovery and characterization of ACT-335827, an orally available, brain penetrant orexin receptor type 1 selective antagonist.

    Science.gov (United States)

    Steiner, Michel A; Gatfield, John; Brisbare-Roch, Catherine; Dietrich, Hendrik; Treiber, Alexander; Jenck, Francois; Boss, Christoph

    2013-06-01

    Stress relief: Orexin neuropeptides regulate arousal and stress processing through orexin receptor type 1 (OXR-1) and 2 (OXR-2) signaling. A selective OXR-1 antagonist, represented by a phenylglycine-amide substituted tetrahydropapaverine derivative (ACT-335827), is described that is orally available, penetrates the brain, and decreases fear, compulsive behaviors and autonomic stress reactions in rats.

  4. Resource Conservation and Recovery Act industrial site environmental restoration site characterization plan. Area 6 Decontamination Pond Facility. Revision 1

    International Nuclear Information System (INIS)

    This plan presents the strategy for the characterization of the Area 6 Decontamination Pond Facility at the Nevada Test Site which will be conducted for the US Department of Energy, Nevada Operations Office, Environmental Restoration Division. The objectives of the planned activities are to: obtain sufficient, sample analytical data from which further assessment, remediation, and/or closure strategies may be developed for the site; obtain sufficient, sample analytical data for management of investigation-derived waste. The scope of the characterization may include surface radiation survey(s), surface soil sampling, subsurface soil boring (i.e., drilling), and sampling of soil in and around the pond; in situ sampling of the soil within subsurface soil borings; and sample analysis for both site characterization and waste management purposes

  5. Transcriptional regulation of the apolipoprotein B100 gene: purification and characterization of trans-acting factor BRF-2.

    OpenAIRE

    Zhuang, H.; Chuang, S S; Das, H. K.

    1992-01-01

    Apolipoprotein B100 (apoB), the only protein of low-density lipoprotein, is produced primarily in the liver and serves as a ligand for the low-density lipoprotein receptor. Hepatic cell-specific expression of the human apoB gene is controlled by at least two cis-acting positive elements located between positions-128 and -70 (H. K. Das, T. Leff, and J.L. Breslow, J. Biol. Chem. 263:11452-11458, 1988). The distal element (-128 to -85) appears to be liver specific since it shows positive activit...

  6. Research and institutional dimensions of environmental justice: Implications for NEPA documentation

    Energy Technology Data Exchange (ETDEWEB)

    Carnes, S.A.; Wolfe, A.K.

    1995-07-01

    Satisfying the environmental justice requirements imposed on the NEPA process is a challenging imperative. Among the challenges for NEPA documentation are: (1) adapting existing disciplinary methodologies that address distributional effects to the dictates of the executive order; (2) determining operational and, perhaps, threshold values for policy directives (e.g., disproportionately high and adverse effects); (3) identifying and involving representatives of minority, Native American, and low-income communities and populations in the NEPA process without jeopardizing their independence and integrity; (4) developing strategies, approaches, and methodologies that are more responsive to the consideration of multiple and cumulative exposures; and (5) developing professional standards for environmental justice assessment that are consistent with the letter and intent of the executive order, protective of the environments of minority, Native American, and low-income populations and communities, and useful to decision makers. This report will address current research and institutional activities associated with these issues, present alternative approaches available for their resolution, and identify the implications of those alternative approaches.

  7. Resource Conservation and Recovery Act industrial site environmental restoration site characterization plan: Area 23, Building 650 Leachfield

    International Nuclear Information System (INIS)

    This plan presents the strategy for the characterization of Corrective Action Unit 94, Area 23, Building 650 Leachfield. It is a land disposal unit, located southeast of Building 650, that was in operation from 1965 to October 1992, with an estimated annual discharge rate of less than 984 liters from designated sinks, floor drains, and emergency decontamination showers in Building 650. The objectives of the planned activities are to: obtain sufficient sample analytical data from which further assessment, remediation, and/or closure strategies may be developed for the site: and obtain sufficient sample analytical data for management of investigation-derived waste (IDW). All references to regulations in this plan are to the versions of the regulations that are current at the time of publication of this plan. The scope of the characterization will include subsurface soil boring (i.e., drilling), in situ sampling of the soil within subsurface soil borings, and sample analysis for both site characterization and waste management purposes

  8. Isolation and characterization of a novel cis-acting sequences regulating root-specific gene from Daucus carota L.

    Institute of Scientific and Technical Information of China (English)

    LIU Yan; GUO Chang-an; REN Haibo; CHEN Fan

    2004-01-01

    Aquaporins are ubiquitous channel proteins that facilitate the transport of water across cell membranes. Most of aquaporins are represent in more than one tissues, but some of them performed highest in roots. They are belived to participate in water transport. DcRB7, a member of the aquaporin family, was isolated from somatic embryos of carrot and identified as a homologous gene of TobRB7. Further studies showed that the expression of DcRB7 was particular in carrot root. To investigate the transcription regulation of DcRB7, a 650-bp upstream sequence of DcRB7 was isolated by inverse PCR, and was fused to the β-glucuronidase (GUS) report gene. After the recombined vectors were transformed into tobacco, the expression pattern was performed by histochemical staining and the quantitative analysis of GUS activity. The results indicated that the cis-acting element of DcRB7 gene directs GUS expression not only as root-specific but also as drought inducible.

  9. Performance test results of noninvasive characterization of Resource Conservation and Recovery Act surrogate waste by prompt gamma neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Gehrke, R.J.; Streier, G.G.

    1997-03-01

    During FY-96, a performance test was carried out with funding from the Mixed Waste Focus Area (MWFA) of the Department of Energy (DOE) to determine the noninvasive elemental assay capabilities of commercial companies for Resource Conservation and Recovery Act (RCRA) metals present in 8-gal drums containing surrogate waste. Commercial companies were required to be experienced in the use of prompt gamma neutron activation analysis (PGNAA) techniques and to have a prototype assay system with which to conduct the test assays. Potential participants were identified through responses to a call for proposals advertised in the Commerce Business Daily and through personal contacts. Six companies were originally identified. Two of these six were willing and able to participate in the performance test, as described in the test plan, with some subsidizing from the DOE MWFA. The tests were conducted with surrogate sludge waste because (1) a large volume of this type of waste awaits final disposition and (2) sludge tends to be somewhat homogeneous. The surrogate concentrations of the above RCRA metals ranged from {approximately} 300 ppm to {approximately} 20,000 ppm. The lower limit was chosen as an estimate of the expected sensitivity of detection required by noninvasive, pretreatment elemental assay systems to be of value for operational and compliance purposes and to still be achievable with state-of-the-art methods of analysis. The upper limit of {approximately} 20,000 ppm was chosen because it is the opinion of the author that assay above this concentration level is within current state-of-the-art methods for most RCRA constituents. This report is organized into three parts: Part 1, Test Plan to Evaluate the Technical Status of Noninvasive Elemental Assay Techniques for Hazardous Waste; Part 2, Participants` Results; and Part 3, Evaluation of and Comments on Participants` Results.

  10. sRecovery Act: Geologic Characterization of the South Georgia Rift Basin for Source Proximal CO2 Storage

    Energy Technology Data Exchange (ETDEWEB)

    Waddell, Michael

    2014-09-30

    This study focuses on evaluating the feasibility and suitability of using the Jurassic/Triassic (J/TR) sediments of the South Georgia Rift basin (SGR) for CO2 storage in southern South Carolina and southern Georgia The SGR basin in South Carolina (SC), prior to this project, was one of the least understood rift basin along the east coast of the U.S. In the SC part of the basin there was only one well (Norris Lightsey #1) the penetrated into J/TR. Because of the scarcity of data, a scaled approach used to evaluate the feasibility of storing CO2 in the SGR basin. In the SGR basin, 240 km (~149 mi) of 2-D seismic and 2.6 km2 3-D (1 mi2) seismic data was collected, process, and interpreted in SC. In southern Georgia 81.3 km (~50.5 mi) consisting of two 2-D seismic lines were acquired, process, and interpreted. Seismic analysis revealed that the SGR basin in SC has had a very complex structural history resulting the J/TR section being highly faulted. The seismic data is southern Georgia suggest SGR basin has not gone through a complex structural history as the study area in SC. The project drilled one characterization borehole (Rizer # 1) in SC. The Rizer #1 was drilled but due to geologic problems, the project team was only able to drill to 1890 meters (6200 feet) instead of the proposed final depth 2744 meters (9002 feet). The drilling goals outlined in the original scope of work were not met. The project was only able to obtain 18 meters (59 feet) of conventional core and 106 rotary sidewall cores. All the conventional core and sidewall cores were in sandstone. We were unable to core any potential igneous caprock. Petrographic analysis of the conventional core and sidewall cores determined that the average porosity of the sedimentary material was 3.4% and the average permeability was 0.065 millidarcy. Compaction and diagenetic studies of the samples determined there would not be any porosity or permeability at depth in SC. In Georgia there appears to be porosity in

  11. ACTS 2014

    DEFF Research Database (Denmark)

    Co-curator of ACTS 2014 together with Rasmus Holmboe, Judith Schwarzbart and Sanne Kofoed. ACTS is the Museum of Contemporary Art’s international bi-annual festival. ACTS was established in 2011 and, while the primary focus is on sound and performance art, it also looks toward socially oriented art...... various possibilities and public spaces as a stage. ACTS takes place in and around the museum and diverse locations in Roskilde city. ACTS is partly curated by the museum staff and partly by guest curators. ACTS 2014 is supported by Nordea-fonden and is a part of the project The Museum goes downtown....

  12. 23 CFR 636.109 - How does the NEPA process relate to the design-build procurement process?

    Science.gov (United States)

    2010-04-01

    ... TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING General § 636.109 How does the NEPA... preliminary design; (2) The contracting agency may permit any design and engineering activities to be... authorization or obligate Federal funds. (d) The FHWA's authorization and obligation of preliminary...

  13. 40 CFR Appendix A to Subpart L - Criteria for Evaluating a State's Proposed NEPA-Like Process

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Criteria for Evaluating a State's Proposed NEPA-Like Process A Appendix A to Subpart L Protection of Environment ENVIRONMENTAL PROTECTION... conditions; (5) Land use and other social parameters including relevant recreation and...

  14. Les lectures de ne...pas : éléments d'une explication modulaire

    DEFF Research Database (Denmark)

    Nølke, Henning

    1994-01-01

    at gøre rede for sammenhængen mellem på den ene side formelle, logiske og semantiske aspekter ved den franske nægtelse ne...pas og på den anden side dens tre hovedfunktioner som metalingvistisk, polemisk og beskrivende nægtelse. I analysen inddrages modulerne for scope (rækkevidde), fokalisering og......Nægtelsen har i naturligt sprog mange forskellige anvendelser. Siden Aristoteles har forskere skelnet mellem sætnings- og prædikatsnægtelse, mellem ekstern og intern nægtelse, mellem nægtelse som handling og nægtelse som beskrivelse, osv. Artiklen forsøger inden for en modulær lingvistisk tilgang...

  15. In Vitro and in Vivo Characterization of MOD-4023, a Long-Acting Carboxy-Terminal Peptide (CTP)-Modified Human Growth Hormone.

    Science.gov (United States)

    Hershkovitz, Oren; Bar-Ilan, Ahuva; Guy, Rachel; Felikman, Yana; Moschcovich, Laura; Hwa, Vivian; Rosenfeld, Ron G; Fima, Eyal; Hart, Gili

    2016-02-01

    MOD-4023 is a novel long-acting version of human growth hormone (hGH), containing the carboxy-terminal peptide (CTP) of human chorionic gonadotropin (hCG). MOD-4023 is being developed as a treatment for adults and children with growth hormone deficiency (GHD), which would require fewer injections than currently available GH formulations and thus reduce patient discomfort and increase compliance. This study characterizes MOD-4023's binding affinities for the growth hormone receptor, as well as the pharmacokinetic and pharmacodynamics, toxicology, and safety profiles of repeated dosing of MOD-4023 in Sprague-Dawley rats and Rhesus monkeys. Although MOD-4023 exhibited reduced in vitro potency and lower affinity to the GH receptor than recombinant hGH (rhGH), administration of MOD-4023 every 5 days in rats and monkeys resulted in exposure comparable to daily rhGH, and the serum half-life of MOD-4023 was significantly longer. Repeated administration of MOD-4023 led to elevated levels of insulin-like growth factor 1 (IGF-1), and twice-weekly injections of MOD-4023 resulted in larger increase in weight gain with fewer injections and a lower accumulative hGH dose. Thus, the increased half-life of MOD-4023 in comparison to hGH may increase the frequency of protein-receptor interactions and compensate for its decreased in vitro potency. MOD-4023 was found to be well-tolerated in rats and monkeys, with minimal adverse events, suggesting an acceptable safety profile. These results provide a basis for the continued clinical development of MOD-4023 as a novel treatment of GHD in children and adults. PMID:26713839

  16. Book Act

    OpenAIRE

    Kivland, Sharon

    2014-01-01

    Book Act was a new project by AMBruno, initiated by Sophie Loss, in which artist book-makers performed and embodied the concept or essence of their books through the medium of film or performance. The exhibition at The Tetley, Leeds, comprised the originating books and corresponding video work, with live performances on Sunday 9 March 2014. Book Act took place during the 17th International Contemporary Artists' Book Fair (7th to 9th March) and the exhibition continued until 26th March 2014.

  17. National Environmental Policy Act source guide for the Hanford Site

    International Nuclear Information System (INIS)

    This Source Guide will assist those working with the National Environmental Policy Act (NEPA) of 1969 to become more familiar with the environmental assessments (EA) and environmental impact statements (EIS) that apply to specific activities and facilities on the Hanford Site. This document should help answer questions concerning NEPA coverage, history, processes, and the status of many of the buildings and units on and related to the Hanford Site. This document summarizes relevant EAs and EISs by briefly outlining the proposed action of each document and the decision made by the US Department of Energy (DOE) or its predecessor agencies, the US Atomic Energy Commission (AEC) and the US Energy Research and Development Administration (ERDA). The summary includes the proposed action alternatives and current status of the proposed action. If a decision officially was stated by the DOE, as in a finding of no significant impact (FONSI) or a record of decision (ROD), and the decision was located, a summary is provided. Not all federal decisions, such as FONSIs and RODS, can be found in the Federal Register (FR). For example, although significant large-action FONSIs can be found in the FR, some low-interest FONSIs might have been published elsewhere (i.e., local newspapers)

  18. National Environmental Policy Act source guide for the Hanford Site

    Energy Technology Data Exchange (ETDEWEB)

    Jansky, M.T.

    1998-09-30

    This Source Guide will assist those working with the National Environmental Policy Act (NEPA) of 1969 to become more familiar with the environmental assessments (EA) and environmental impact statements (EIS) that apply to specific activities and facilities on the Hanford Site. This document should help answer questions concerning NEPA coverage, history, processes, and the status of many of the buildings and units on and related to the Hanford Site. This document summarizes relevant EAs and EISs by briefly outlining the proposed action of each document and the decision made by the US Department of Energy (DOE) or its predecessor agencies, the US Atomic Energy Commission (AEC) and the US Energy Research and Development Administration (ERDA). The summary includes the proposed action alternatives and current status of the proposed action. If a decision officially was stated by the DOE, as in a finding of no significant impact (FONSI) or a record of decision (ROD), and the decision was located, a summary is provided. Not all federal decisions, such as FONSIs and RODS, can be found in the Federal Register (FR). For example, although significant large-action FONSIs can be found in the FR, some low-interest FONSIs might have been published elsewhere (i.e., local newspapers).

  19. Environmental assessment for the Groundwater Characterization Project, Nevada Test Site, Nye County, Nevada; Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1992-08-01

    The US Department of Energy (DOE) proposes to conduct a program to characterize groundwater at the Nevada Test Site (NTS), Nye County, Nevada, in accordance with a 1987 DOE memorandum stating that all past, present, and future nuclear test sites would be treated as Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) sites (Memorandum from Bruce Green, Weapons Design and Testing Division, June 6, 1987). DOE has prepared an environmental assessment (DOE/EA-0532) to evaluate the environmental consequences associated with the proposed action, referred to as the Groundwater Characterization Project (GCP). This proposed action includes constructing access roads and drill pads, drilling and testing wells, and monitoring these wells for the purpose of characterizing groundwater at the NTS. Long-term monitoring and possible use of these wells in support of CERCLA, as amended by the Superfund Amendments and Reauthorization Act, is also proposed. The GCP includes measures to mitigate potential impacts on sensitive biological, cultural and historical resources, and to protect workers and the environment from exposure to any radioactive or mixed waste materials that may be encountered. DOE considers those mitigation measures related to sensitive biological, cultural and historic resources as essential to render the impacts of the proposed action not significant, and DOE has prepared a Mitigation Action Plan (MAP) that explains how such mitigations will be planned and implemented. Based on the analyses presented in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act of 1969 (NEPA). Therefore, preparation of an environmental impact statement is not required and the Department is issuing this FONSI.

  20. Environmental assessment for the Groundwater Characterization Project, Nevada Test Site, Nye County, Nevada

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) proposes to conduct a program to characterize groundwater at the Nevada Test Site (NTS), Nye County, Nevada, in accordance with a 1987 DOE memorandum stating that all past, present, and future nuclear test sites would be treated as Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) sites (Memorandum from Bruce Green, Weapons Design and Testing Division, June 6, 1987). DOE has prepared an environmental assessment (DOE/EA-0532) to evaluate the environmental consequences associated with the proposed action, referred to as the Groundwater Characterization Project (GCP). This proposed action includes constructing access roads and drill pads, drilling and testing wells, and monitoring these wells for the purpose of characterizing groundwater at the NTS. Long-term monitoring and possible use of these wells in support of CERCLA, as amended by the Superfund Amendments and Reauthorization Act, is also proposed. The GCP includes measures to mitigate potential impacts on sensitive biological, cultural and historical resources, and to protect workers and the environment from exposure to any radioactive or mixed waste materials that may be encountered. DOE considers those mitigation measures related to sensitive biological, cultural and historic resources as essential to render the impacts of the proposed action not significant, and DOE has prepared a Mitigation Action Plan (MAP) that explains how such mitigations will be planned and implemented. Based on the analyses presented in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act of 1969 (NEPA). Therefore, preparation of an environmental impact statement is not required and the Department is issuing this FONSI

  1. 《傲慢与偏见》中微观言语行为与人物刻画——以伊丽莎白为例%The Micro-Speech Acts and Characterization in Pride and Prejudice:A Case Study of Elizabeth's Four Typical Micro-Speech Acts

    Institute of Scientific and Technical Information of China (English)

    王军

    2011-01-01

    运用言语行为理论分析《傲慢与偏见》中个性鲜明的女主人公伊丽莎白的四种典型微观言语行为——讽刺、嘲弄、悔恨、道歉,说明人物的性格特征,可以得出结论,即言语行为在人物刻画过程中能够起到关键性作用,而言语行为理论则可以为文学文本解读提供一个崭新的视角。%By using Speech Act Theory,this paper analyzes the four typical micro-speech acts of the heroine in Pride and Prejudice,Elizabeth,who has striking personality traits.Through the analysis,the conclusion can be reached that speech acts play a key role in the characterization and Speech Act Theory can provide a new perspective for the interpretation of literary texts.

  2. Phenotypic and molecular characterization of CTX-M-14 extended-spectrum β-lactamase and plasmid-mediated ACT-like AmpC β-lactamase produced by Klebsiella pneumoniae isolates from chickens in Henan Province, China.

    Science.gov (United States)

    Wu, H; Liu, B-G; Liu, J-H; Pan, Y-S; Yuan, L; Hu, G-Z

    2012-01-01

    Extended-spectrum β-lactamases (ESBLs) and AmpC β-lactamases produced by a clinical isolate of Klebsiella pneumoniae from chickens were detected with confirmatory phenotypic tests of the Clinical and Laboratory Standards Institute. The minimum inhibitory concentrations of 18 antibacterial drugs against K. pneumoniae were determined by the 2-fold microdilution method. The genotype and subtype of the ESBL-producing and AmpC β-lactamase-producing K. pneumoniae isolate were identified by PCR amplification of the enzyme-encoding genes followed by DNA sequencing analysis. K. pneumoniae K(1) isolate was an ESBL-producing and AmpC β-lactamase-producing bacteria with high resistance to β-lactam antibiotics, such as penicillins, third-generation cephalosporins, fluoroquinolones, and aminoglycosides. The sequence analysis showed that K. pneumoniae K(1) harbored TEM-type, SHV-type, CTX-M-type, and ACT-type AmpC β-lactamase nucleotide sequences. The TEM-type sequence was designated as TEM-1; the SHV-type sequence was designated as SHV-11; the CTX-M-type sequence was designated as CTX-M-14. Compared with the ACT-like sequence (EF078894), the ACT-type sequence was characterized by 8 nucleotide mutations (A(75)G, C(84)G, T(90)C, A(105)G, G(213)A, G(246)A, C(309)T, and T(315)C). Only one mutation at position 75 led to an amino acid substitution (Asn28Lys). The bla(ACT) type was an ACT-like derivative. PMID:23079829

  3. Site characterization progress report: Yucca Mountain, Nevada, April 1, 1991--September 30, 1991, Number 5; Nuclear Waste Policy Act (Section 113)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1992-06-01

    The Site Characterization Progress Report of Yucca Mountain (PR) presents brief summaries of the status of site characterization activities and cites the technical reports and research products that provide more detailed information on the activities. The report provides highlights of work started during the reporting period, work in progress, and work completed and documented during the reporting period. In addition, the report is the vehicle for the discussion of changes to the DOE`s site characterization program resulting from ongoing collection and evaluation of site information; the development of repository and waste-package designs; the results of performance assessments; and any changes that occur in response to external comments. Information covered includes geochemistry, hydrology, geology, climate, and radiation dose estimate calculations.

  4. Duel-acting subcutaneous microemulsion formulation for improved migraine treatment with zolmitriptan and diclofenac: formulation and in vitro-in vivo characterization.

    Science.gov (United States)

    Dubey, R; Martini, Luigi G; Christie, Mark

    2014-03-01

    Subcutaneous triptan provides immediate analgesia in migraine and cluster headache but is limited by high pain recurrence due to rapid drug elimination. A dual-acting subcutaneous formulation providing immediate release of a triptan and slow but sustained release of a nonsteroidal anti-inflammatory drug may provide a longer duration of relief. A microemulsion-based technology has various advantages over other technically complex dosage forms. Oil-in-water microemulsions of zolmitriptan and diclofenac acid using Labrafac Lipophile, Tween 80, Capryol 90 and water were prepared. One formulation was characterised in vitro and found to have uniformly dispersed nanosized globules. The formulation provided differential release of zolmitriptan and diclofenac acid both in vitro as well as in vivo that may be potentially beneficial to migraine patients. PMID:24363199

  5. Cloning of the full-length gene of activin receptor-interacting protein2a and characterization of its interaction with ActR Ⅱ A

    Institute of Scientific and Technical Information of China (English)

    CUI Xueling; TAI Guixiang; ZHANG Hongjun; FANG Lin; LIU Zhonghui

    2007-01-01

    To investigate the mechanism of intracellular signal transduction mediated by activin receptors, the full-length gene encoding a novel activin receptor-interacting protein2a (ARIP2a) was identified from a mouse brain cDNA library. The sequences of ARIP2a and ARIP2, distribution of ARIP2a and ARIP2 mRNA in mouse tissues, and expression of ARIP2a and ARIP2 in activin-induced RAW264.7 cell were compared, and the interaction between ARIP2a and ActRIIA was confirmed. The sequence analysis revealed that the full-length gene of ARIP2a, which composed of 1008 bp and encoded 153 amino acid residues, shared high sequence identity with ARIP2 except the position of the 99th amino acid. RT-PCR assay showed that ARIP2a mRNA was highly expressed in brain, pituitary and testis, and moderately in pancreas and ovary, but undetectable in other tissues. Whereas, ARIP2 mRNA was widely distributed in all mouse tissues that we tested. Moreover, expression of ARIP2a mRNA was significantly decreased in activin-stimulated RAW264.7 cells;however, the expression of ARIP2 mRNA was increased. Additionally, the interaction between ARIP2a and activin type ⅡA receptor (ActRIIA) was further demonstrated by mammalian two-hybrid assays and pull-down assays. Taken together, those results indicate that although ARIP2a is homologous to ARIP2, they are different in tissue distribution and responses to activin. ARIP2a could also interact with activin type Ⅱ receptor as a novel member of ARIP family.

  6. Act resilient.

    Science.gov (United States)

    Joseph, Genie; Bice-Stephens, Wynona

    2014-01-01

    Attendees have reported changing from being fearful to serene, from listless to energized, from disengaged to connected, and becoming markedly less anxious in a few weeks. Anecdotally, self-reported stress levels have been reduced by over 50% after just one class. Attendees learn not to be afraid of their feelings by working with emotions in a playful manner. When a person can act angry, but separate himself from his personal story, the emotional energy exists in a separate form that is not attached to specific events, and can be more easily dealt with and neutralized. Attendees are taught to "take out the emotional trash" through expressive comedy. They become less intimated by their own emotional intensity and triggers as they learn how even metaphorical buckets of anger, shame, guilt and hurt can be emotionally emptied. The added benefit is that this is accomplished without the disclosure of personal information of the requirement to reexperience past pain which can trigger its own cascade of stress. PMID:24706248

  7. Geothermal Development and the Use of Categorical Exclusions Under the National Environmental Policy Act of 1969 (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Levine, A.; Young, K. R.

    2014-09-01

    The federal environmental review process under the National Environmental Policy Act of 1969 (NEPA) can be complex and time consuming. Currently, a geothermal developer may have to complete the NEPA process multiple times during the development of a geothermal project. One mechanism to reduce the timeframe of the federal environmental review process for activities that do not have a significant environmental impact is the use of Categorical Exclusions (CXs), which can exempt projects from having to complete an Environmental Assessment or Environmental Impact Statement. This study focuses primarily on the CX process and its applicability to geothermal exploration. In this paper, we: Provide generalized background information on CXs, including previous NEPA reports addressing CXs, the process for developing CXs, and the role of extraordinary circumstances; Examine the history of the Bureau of Land Management's (BLM) geothermal CXs; Compare current CXs for oil, gas, and geothermal energy; Describe bills proposing new statutory CXs; Examine the possibility of standardizing geothermal CXs across federal agencies; and Present analysis from the Geothermal NEPA Database and other sources on the potential for new geothermal exploration CXs. As part of this study, we reviewed Environmental Assessments (EAs) conducted in response to 20 geothermal exploration drilling permit applications (Geothermal Drilling Permits or Notices of Intents) since the year 2001, the majority of which are from the last 5 years. All 20 EAs reviewed for this study resulted in a Finding of No Significant Impact (FONSI). While many of these FONS's involved proponent proposed or federal agency required mitigation, this still suggests it may be appropriate to create or expand an exploration drilling CX for geothermal, which would have a significant impact on reducing geothermal exploration timelines and up-front costs. Ultimately, federal agencies tasked with permitting and completing

  8. 30 CFR 285.611 - What information must I submit with my SAP to assist MMS in complying with NEPA and other...

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What information must I submit with my SAP to... Assessment Plan § 285.611 What information must I submit with my SAP to assist MMS in complying with NEPA and other relevant laws? (a) You must submit with your SAP detailed information to assist MMS in...

  9. Characterization of Xanthomonas oryzae-Responsive cis-Acting Element in the Promoter of Rice Race-Specific Susceptibility Gene Xa13

    Institute of Scientific and Technical Information of China (English)

    Ting Yuan; Xianghua Li; Jinghua Xiao; Shiping Wang

    2011-01-01

    The rice Xa13 gene,whose promoter harbors a UPT (up-regulated by transcription activator-like [TAL] effector) box,UPTPthXo1,plays a pivotal role in the race-specific pathogenicity caused by Xanthomonas oryzae pv. Oryzae (Xoo) strain PXO99. PXO99 causes rice disease by inducing Xa13. It is unknown,however,whether the UPTPthXo1 box is the only PXO99-responsive c/s-regulating elements in the activation of Xa13 expression. We analyzed the expression of a series of end- and site-truncated and site-mutated Xa 13 promoters in rice and the binding of PXO99 protein to the intact,partial,or site-mutated UPTPthXo1 boxes. In the Xa13 promoter,UPTPthXo1 box is the only Xoo-responsive cis-acting element that results in PXO99-induced Xa13 expression. The 5'-terminal second,third,and fourth nucleotides of the box are important for bacterial protein binding and gene activation;mutation of any one of these sites abolished PXO99-induced gene expression. Furthermore,the 3'-half of the UPTPthXo1 box is also required for protein binding and gene activation. These findings will enhance our understanding of the molecular mechanism of the interaction of rice and Xoo via UPT boxes and TAL effectors.

  10. Expression and Characterization of a Potent Long-Acting GLP-1 Receptor Agonist, GLP-1-IgG2σ-Fc.

    Science.gov (United States)

    Yang, Yi; Chen, Fang; Wan, Deyou; Liu, Yunhui; Yang, Li; Feng, Hongru; Cui, Xinling; Gao, Xin; Song, Haifeng

    2016-01-01

    Human GLP-1 (glucagon-like peptide-1) can produce a remarkable improvement in glycemic control in patients with type 2 diabetes. However, its clinical benefits are limited by its short half-life, which is less than 2 min because of its small size and rapid enzymatic inactivation by dipeptidyl peptidase IV. We engineered GLP-1-IgG2σ-Fc, a 68-kDa fusion protein linking a variant human GLP-1 (A8G/G26E/R36G) to a human IgG2σ constant heavy-chain. A stably transfected Chinese hamster ovary cell line was obtained using electroporation. Western blotting showed that the expressed protein was immunoreactive to both GLP-1 and IgG antibodies. GLP-1-IgG2σ-Fc stimulated insulin secretion from INS-1 cells in a dose- and glucose-dependent manner and increased insulin mRNA expression. The half-life of GLP-1-IgG2σ-Fc in cynomolgus monkeys was approximately 57.1 ± 4.5 h. In the KKAy mouse model of diabetes, one intraperitoneal injection of GLP-1-IgG2σ-Fc (1 mg/kg) reduced blood glucose levels for 5 days. A 4-week repeat-administration study identified sustained effects on blood glucose levels. Oral glucose tolerance tests conducted at the beginning and end of this 4-week period showed that GLP-1-IgG2σ-Fc produced a stable glucose lowering effect. In addition, KKAy mice treated with GLP-1-IgG2σ-Fc showed statistically significant weight loss from day 23. In conclusion, these properties of GLP-1-IgG2σ-Fc demonstrated that it represented a potential long-acting GLP-1 receptor agonist for the treatment of type 2 diabetes. PMID:27232339

  11. Expression and Characterization of a Potent Long-Acting GLP-1 Receptor Agonist, GLP-1-IgG2σ-Fc.

    Directory of Open Access Journals (Sweden)

    Yi Yang

    Full Text Available Human GLP-1 (glucagon-like peptide-1 can produce a remarkable improvement in glycemic control in patients with type 2 diabetes. However, its clinical benefits are limited by its short half-life, which is less than 2 min because of its small size and rapid enzymatic inactivation by dipeptidyl peptidase IV. We engineered GLP-1-IgG2σ-Fc, a 68-kDa fusion protein linking a variant human GLP-1 (A8G/G26E/R36G to a human IgG2σ constant heavy-chain. A stably transfected Chinese hamster ovary cell line was obtained using electroporation. Western blotting showed that the expressed protein was immunoreactive to both GLP-1 and IgG antibodies. GLP-1-IgG2σ-Fc stimulated insulin secretion from INS-1 cells in a dose- and glucose-dependent manner and increased insulin mRNA expression. The half-life of GLP-1-IgG2σ-Fc in cynomolgus monkeys was approximately 57.1 ± 4.5 h. In the KKAy mouse model of diabetes, one intraperitoneal injection of GLP-1-IgG2σ-Fc (1 mg/kg reduced blood glucose levels for 5 days. A 4-week repeat-administration study identified sustained effects on blood glucose levels. Oral glucose tolerance tests conducted at the beginning and end of this 4-week period showed that GLP-1-IgG2σ-Fc produced a stable glucose lowering effect. In addition, KKAy mice treated with GLP-1-IgG2σ-Fc showed statistically significant weight loss from day 23. In conclusion, these properties of GLP-1-IgG2σ-Fc demonstrated that it represented a potential long-acting GLP-1 receptor agonist for the treatment of type 2 diabetes.

  12. Review and critique of the US Department of Energy environmental program plan for site characterization for a high-level waste repository at Yucca Mountain, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1992-12-31

    This report provides a review and critique of the US Department of Energy (DOE) environmental program plan for site characterization activities at Yucca Mountain which principally addresses compliance with federal and state environmental regulation and to a lesser extent monitoring and mitigation of significant adverse impacts and reclamation of disturbed areas. There are 15 documents which comprise the plan and focus on complying with the environmental requirements of the Nuclear Waste Policy Act, as amended, (NWPA) and with single-media environmental statutes and their regulations. All elements of the plan follow from the 1986 statutory environmental assessment (EA) required by NWPA which concluded that no significant adverse impacts would result from characterization of the Yucca Mountain site. The lack of appropriate environmental planning and review for site characterization at Yucca Mountain points to the need for an oversight function by the State of Nevada. It cannot be assumed that on its own DOE will properly comply with environmental requirements, especially the substantive requirements that comprise the intent of NEPA. Thus, procedures must be established to assure that the environmental interests of the State are addressed in the course of the Yucca Mountain Project. Accordingly, steps will be taken by the State of Nevada to review the soundness and efficacy of the DOE field surveys, monitoring and mitigation activities, reclamation actions, and ecological impact studies that follow from the DOE environmental program plans addressed by this review.

  13. Site characterization progress report: Yucca Mountain, Nevada, October 1, 1994--March 31, 1995, Number 12. Nuclear Waste Policy Act (Section 113)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    During the first half of fiscal year 1995, most activities at the Yucca Mountain Site Characterization Project were directed at implementing the Program Plan developed by the Office of Civilian Radioactive Waste Management. The Plan is designed to enable the Office to make measurable and significant progress toward key objectives over the next five years within the financial resources that can be realistically expected. Activities this period focused on the immediate goal of determining by 1998 whether Yucca Mountain, Nevada, is technically suitable as a possible site for a geologic repository for the permanent disposal of spent nuclear fuel and high-level radioactive waste. Work on the Project advanced in several critical areas, including programmatic activities such as issuing the Program Plan, completing the first technical basis report to support the assessment of three 10 CFR 960 guidelines, developing the Notice of Intent for the Environmental Impact Statement, submitting the License Application Annotated Outline, and beginning a rebaselining effort to conform with the goals of the Program Plan. Scientific investigation and analysis of the site and design and construction activities to support the evaluation of the technical suitability of the site also advanced. Specific details relating to all Project activities and reports generated are presented in this report.

  14. Site characterization progress report: Yucca Mountain, Nevada, October 1, 1994--March 31, 1995, Number 12. Nuclear Waste Policy Act (Section 113)

    International Nuclear Information System (INIS)

    During the first half of fiscal year 1995, most activities at the Yucca Mountain Site Characterization Project were directed at implementing the Program Plan developed by the Office of Civilian Radioactive Waste Management. The Plan is designed to enable the Office to make measurable and significant progress toward key objectives over the next five years within the financial resources that can be realistically expected. Activities this period focused on the immediate goal of determining by 1998 whether Yucca Mountain, Nevada, is technically suitable as a possible site for a geologic repository for the permanent disposal of spent nuclear fuel and high-level radioactive waste. Work on the Project advanced in several critical areas, including programmatic activities such as issuing the Program Plan, completing the first technical basis report to support the assessment of three 10 CFR 960 guidelines, developing the Notice of Intent for the Environmental Impact Statement, submitting the License Application Annotated Outline, and beginning a rebaselining effort to conform with the goals of the Program Plan. Scientific investigation and analysis of the site and design and construction activities to support the evaluation of the technical suitability of the site also advanced. Specific details relating to all Project activities and reports generated are presented in this report

  15. Supplement analysis of transuranic waste characterization and repackaging activities at the Idaho National Engineering Laboratory in support of the Waste Isolation Pilot Plant test program

    International Nuclear Information System (INIS)

    This supplement analysis has been prepared to describe new information relevant to waste retrieval, handling, and characterization at the Idaho National Engineering Laboratory (INEL) and to evaluate the need for additional documentation to satisfy the National Environmental Policy Act (NEPA). The INEL proposes to characterize and repackage contact-handled transuranic waste to support the Waste Isolation Pilot Plant (WIPP) Test Phase. Waste retrieval, handling and processing activities in support of test phase activities at the WIPP were addressed in the Supplemental Environmental Impact Statement (SEIS) for the WIPP. To ensure that test-phase wastes are properly characterized and packaged, waste containers would be retrieved, nondestructively examined, and transported from the Radioactive Waste Management Complex (RWMC) to the Hot-Fuel Examination Facility for headspace gas analysis, visual inspections to verify content code, and waste acceptance criteria compliance, then repackaging into WIPP experimental test bins or returned to drums. Following repackaging the characterized wastes would be returned to the RWMC. Waste characterization would help DOE determine WIPP compliance with US Environmental Protection Agency regulations governing disposal of transuranic waste and hazardous waste. Additionally, this program supports onsite compliance with Resource Conservation and Recovery Act (RCRA) requirements, compliance with the terms of the No-Migration Variance at WIPP, and provides data to support future waste shipments to WIPP. This analysis will help DOE determine whether there have been substantial changes made to the proposed action at the INEL, or if preparation of a supplement to the WIPP Final Environmental Impact Statement (DOE, 1980) and SEIS (DOE, 1990a) is required. This analysis is based on current information and includes details not available to the SEIS

  16. 7 CFR 799.5 - FSA officials and offices responsible for carrying out NEPA.

    Science.gov (United States)

    2010-01-01

    ... SERVICE AGENCY, DEPARTMENT OF AGRICULTURE ENVIRONMENTAL PROTECTION ENVIRONMENTAL QUALITY AND RELATED ENVIRONMENTAL CONCERNS-COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL POLICY ACT § 799.5 FSA officials and offices... responsibility with the assistance of the FSA representative on the USDA Environmental Quality Committee,...

  17. PROFILE: Environmental Impact Assessment Under the National Environmental Policy Act and the Protocol on Environmental Protection to the Antarctic Treaty.

    Science.gov (United States)

    Ensminger; McCold; Webb

    1999-07-01

    / Antarctica has been set aside by the international community for protection as a natural reserve and a place for scientific research. Through the Antarctic Treaty of 1961, the signing nations agreed to cooperate in protecting the antarctic environment, in conducting scientific studies, and in abstaining from the exercise of territorial claims. The 1991 signing of the Protocol on Environmental Protection to the Antarctic Treaty (Protocol) by representatives of the 26 nations comprising the Antarctic Treaty Consultative Parties (Parties) significantly strengthened environmental protection measures for the continent. The Protocol required ratification by each of the governments individually prior to official implementation. The US government ratified the Protocol by passage of the Antarctic Science, Tourism, and Conservation Act of 1997. Japan completed the process by ratifying the Protocol on December 15, 1997. US government actions undertaken in Antarctica are subject to the requirements of both the Protocol and the US National Environmental Policy Act (NEPA). There are differences in the scope and intent of the Protocol and NEPA; however, both require environmental impact assessment (EIA) as part of the planning process for proposed actions that have the potential for environmental impacts. In this paper we describe the two instruments and highlight key similarities and differences with particular attention to EIA. Through this comparison of the EIA requirements of NEPA and the Protocol, we show how the requirements of each can be used in concert to provide enhanced environmental protection for the antarctic environment. NEPA applies only to actions of the US government; therefore, because NEPA includes certain desirable attributes that have been refined and clarified through numerous court cases, and because the Protocol is just entering implementation internationally, some recommendations are made for strengthening the procedural requirements of the Protocol

  18. ACT UP as a Structure of Feeling

    Science.gov (United States)

    Gingrich-Philbrook, Craig

    2012-01-01

    Revisiting AIDS Coalition to Unleash Power (ACT UP) restarts the "panic of loss" characterizing the author's youth. The author argues that the 25th anniversary of ACT UP marks the failure to consider Raymond Williams's "structure of feeling". Williams counterposes this structure against falsely viewing the past as formalized into something…

  19. Site Selection & Characterization Status Report for Next Generation Nuclear Plant (NGNP)

    Energy Technology Data Exchange (ETDEWEB)

    Mark Holbrook

    2007-09-01

    In the near future, the US Department of Energy (DOE) will need to make important decisions regarding design and construction of the Next Generation Nuclear Plant (NGNP). One part of making these decisions is considering the potential environmental impacts that this facility may have, if constructed here at the Idaho National Laboratory (INL). The National Environmental Policy Act (NEPA) of 1969 provides DOE decision makers with a process to systematically consider potential environmental consequences of agency decisions. In addition, the Energy Policy Act of 2005 (Title VI, Subtitel C, Section 644) states that the 'Nuclear Regulatory Commission (NRC) shall have licensing and regulatory authority for any reactor authorized under this subtitle.' This stipulates that the NRC will license the NGNP for operation. The NRC NEPA Regulations (10 CFR Part 51) require tha thte NRC prepare an Environmental Impact Statement (EIS) for a permit to construct a nuclear power plant. The applicant is required to submit an Environmental report (ER) to aid the NRC in complying with NEPA.

  20. 75 FR 13139 - The National Environmental Policy Act Procedures Manual

    Science.gov (United States)

    2010-03-18

    ... comments on the Draft NEPA Procedures Manual published in the Federal Register on December 4, 2009 (74 FR 63765-74 FR 63787). Previously, the Commission reopened the comment period from January 19, 2010, to March 4, 2010 (75 FR 3756). ] DATES: The comment period for the Draft NEPA Procedures Manual is...

  1. Nuclear Regulatory Authority Act, 2015 (Act 895)

    International Nuclear Information System (INIS)

    An Act to establish a Nuclear Regulatory Authority in Ghana. This Act provides for the regulation and management of activities and practices for the peaceful use of nuclear material or energy, and to provide for the protection of persons and the environment against the harmful effects of radiation; and to ensure the effective implementation of the country’s international obligations and for related matters. This Act replaced the Radiation Protection Instrument, of 1993 (LI 1559).

  2. Lessons learned and new challenges for integrated assessment under the National Environmental Policy Act

    Energy Technology Data Exchange (ETDEWEB)

    Carnes, S.A.; Reed, R.M.

    1995-12-31

    One of the first government-sponsored demands for integrated assessment to support decision making in the United States is embodied in the National Environmental Policy Act of 1969 (NEPA). Over the past 25 years, Oak Ridge National Laboratory (ORNL) has supported federal agencies` in evaluating health and environmental impacts as required by NEPA. Many of ORNL`s efforts have focused on complex, programmatic assessments that break new ground and require and integrate expertise from a wide range of technical disciplines. Examples of ORNL projects that illustrate the use of integrated assessment approaches include environmental documentation for: (1) the Department of the Army`s Chemical Stockpile Disposal Program, (2) the Federal Energy Regulatory Commission`s licensing activities related to the Owens River Basin in eastern California and along a 500-mile reach of the upper Ohio River, and (3) the Nuclear Regulatory Commission`s decision regarding restart of the undamaged reactor (Unit 1) at Three Mile Island. Our discussion of these examples illustrates successful integrated assessment approaches and identifies new challenges facing integrated assessment activities.

  3. Addressing environmental justice under the National Environment Policy Act at Sandia National Laboratories/New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, T.M.; Bleakly, D.R.

    1997-04-01

    Under Executive Order 12898, Federal Actions to Address Environmental Justice in Minority Populations and Low-Income Populations, the Department of Energy (DOE) and Sandia National Laboratories New Mexico (SNL) are required to identify and address, as appropriate, disproportionately high, adverse human health or environmental effects of their activities on minority and low-income populations. The National Environmental Policy Act (NEPA) also requires that environmental justice issues be identified and addressed. This presents a challenge for SNL because it is located in a culturally diverse area. Successfully addressing potential impacts is contingent upon accurately identifying them through objective analysis of demographic information. However, an effective public participation process, which is necessarily subjective, is also needed to understand the subtle nuances of diverse populations that can contribute to a potential impact, yet are not always accounted for in a strict demographic profile. Typically, there is little or no coordination between these two disparate processes. This report proposes a five-step method for reconciling these processes and uses a hypothetical case study to illustrate the method. A demographic analysis and community profile of the population within 50 miles of SNL were developed to support the environmental justice analysis process and enhance SNL`s NEPA and public involvement programs. This report focuses on developing a methodology for identifying potentially impacted populations. Environmental justice issues related to worker exposures associated with SNL activities will be addressed in a separate report.

  4. Marine Mammal Protection Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Marine Mammal Protection Act (MMPA or Act) prohibits, with certain exceptions, the "take" of marine mammals in U.S. waters and by U.S. citizens on the high...

  5. Assertive Community Treatment (ACT)

    Science.gov (United States)

    ... services—including both ER visits and inpatient hospitalizations—ACT team members are also well-connected with local hospitals and have the ability to work with hospital and emergency room staff. ACT teams ...

  6. ACTS data center

    Science.gov (United States)

    Syed, Ali; Vogel, Wolfhard J.

    1993-01-01

    Viewgraphs on ACTS Data Center status report are included. Topics covered include: ACTS Data Center Functions; data flow overview; PPD flow; RAW data flow; data compression; PPD distribution; RAW Data Archival; PPD Audit; and data analysis.

  7. Nuclear Installations Act 1965

    International Nuclear Information System (INIS)

    This Act governs all activities related to nuclear installations in the United Kingdom. It provides for the licensing procedure for nuclear installations, the duties of licensees, the competent authorities and carriers of nuclear material in respect of nuclear occurrences, as well as for the system of third party liability and compensation for nuclear damage. The Act repeals the Nuclear Installations (Licensing and Insurance) Act 1959 and the Nuclear Installations (Amendment Act) 1965 except for its Section 17(2). (NEA)

  8. Forgetting ACT UP

    Science.gov (United States)

    Juhasz, Alexandra

    2012-01-01

    When ACT UP is remembered as the pinnacle of postmodern activism, other forms and forums of activism that were taking place during that time--practices that were linked, related, just modern, in dialogue or even opposition to ACT UP's "confrontational activism"--are forgotten. In its time, ACT UP was embedded in New York City, and a larger world,…

  9. Indirect Speech Acts

    Institute of Scientific and Technical Information of China (English)

    李威

    2001-01-01

    Indirect speech acts are frequently used in verbal communication, the interpretation of them is of great importance in order to meet the demands of the development of students' communicative competence. This paper, therefore, intends to present Searle' s indirect speech acts and explore the way how indirect speech acts are interpreted in accordance with two influential theories. It consists of four parts. Part one gives a general introduction to the notion of speech acts theory. Part two makes an elaboration upon the conception of indirect speech act theory proposed by Searle and his supplement and development of illocutionary acts. Part three deals with the interpretation of indirect speech acts. Part four draws implication from the previous study and also serves as the conclusion of the dissertation.

  10. ACT Verbal Prep Course

    CERN Document Server

    Standridge, Nathan

    2012-01-01

    Comprehensive Prep for ACT Verbal. Every year, students pay 1,000 and more to test prep companies to prepare for the verbal sections of the ACT. Now you can get the same preparation in a book. The verbal sections are not easy. There is no quick fix that will allow you to "beat" the ACT, but it is very learnable. If you study hard and master the techniques in this book, your score will improve-significantly. The ACT cannot be "beaten." But it can be mastered-through hard work, analytical thought, and by training yourself to think like a test writer. Many of the exercises in this book are design

  11. Radiological Protection Act 1970

    International Nuclear Information System (INIS)

    This Act provides for the establishment of a Radiological Protection Board to undertake research and advise on protection from radiation hazards. Its functions include provision of advice to Government departments with responsibilities in relation to protection of sectors of the community or the community as a whole against the hazards of ionizing radiation. The Act, which lays down that the Board shall replace certain departments concerned with radiation protection, repeals several Sections of the Radioactive Substances Act 1948 and the Science and Technology Act 1965. (NEA)

  12. A Review of NEPA, a Novel Fixed Antiemetic Combination with the Potential for Enhancing Guideline Adherence and Improving Control of Chemotherapy-Induced Nausea and Vomiting

    Directory of Open Access Journals (Sweden)

    Paul J. Hesketh

    2015-01-01

    Full Text Available Combination antiemetic regimens targeting multiple molecular pathways associated with emesis have become the standard of care for prevention of chemotherapy-induced nausea and vomiting (CINV related to highly and moderately emetogenic chemotherapies. Antiemetic consensus guidelines from several professional societies are widely available and updated regularly as new data emerges. Unfortunately, despite substantial research supporting the notion that guideline conformity improves CINV control, adherence to antiemetic guidelines is unsatisfactory. While studies are needed to identify specific barriers to guideline use and explore measures to enhance adherence, a novel approach has been taken to improve clinician adherence and patient compliance, with the development of a new combination antiemetic. NEPA is an oral fixed combination of a new highly selective NK1 receptor antagonist (RA, netupitant, and the pharmacologically and clinically distinct 5-HT3 RA, palonosetron. This convenient antiemetic combination offers guideline-consistent prophylaxis by targeting two critical pathways associated with CINV in a single oral dose administered only once per cycle. This paper will review and discuss the NEPA data in the context of how this first combination antiemetic may overcome some of the barriers interfering with adherence to antiemetic guidelines, enhance patient compliance, and offer a possible advance in the prevention of CINV for patients.

  13. The unity of Luke-Acts

    Directory of Open Access Journals (Sweden)

    J. Verheyden

    1999-01-01

    Full Text Available The article contains a summary of contributions delivered at he 47th Colloquium Biblicum Lovaniense (1998 held at the Catholic University, Leuven on the subject: "The unity of Luke-Acts". The opening address was delivered by J Verheyden (Leuven on "The Unity of Luke and Acts: What are we up to?". The contributors were: J Kremer (Vienna - "Die dreifache Wiedergabe des Damaskuserlebnis Pauli in der Apostelgeschichte: Eine Hilfe für das rechte Verständnis der lukanischen Osterevangelien"; D Marguerat (Lausanne -"Jusqu' où faut-il parler d'une "unité". Luc-Actes? Continuity et ruptures dans I'ævre de Luc"; JDelobel (Leuven - "The text of Luke-Acts: A confrontation of recent theories"; R L Brawley (Chicago - "Abrahamic covenant traditions and the characterization of God in Luke-Acts"; F W Horn (Mainz - "Die Haltung des Lukas zum römischen Staat im Evangelium und in der Apostelgeschichte"; J A Fitzmyer (Washington - "The role of theSpirit in Luke-Acts"; M Rese (Munster - "The Jews in Luke-Acts: Some secondthoughts"; J Taylor (Jerusalem - "La fraction du pain en Luc-Actes"; W Radl (Augs-burg - "Die Beziehungen der Vorgeschichte zur Apostelgeschichte, dargestellt an Lk 2:22-39; F Neirynck (Leuven - "Luke 4:16-30 and the unity of Luke-Acts"; C M Tuckett (Oxford - "The Christology of Luke-Acts"; O Mainville (Montreal - "Le messianisme de Jésus: Le rapport announce/accomplissement entre Lc 1,35 et Ac 2,33"; A Lindemann (Bethel-Bielefeld - "Form und Funktion von Reden und Wundererzählungen im Lukas-evangelium und in der Apostelgeschichte", A Denaux - The theme of divine visits and human (inhospitability in Luke-Acts and its Old Testament and Graeco-Roman antecedents.

  14. Final Report on DANCEE-NFNA-NERI-NEPA-Gene Modified Organisms (GMO) Workshop for the Baltic Countries Estonia - Latvia - Lithuania in Collaboration with CEE Biosafety and BEF, January 23-30, 2001

    DEFF Research Database (Denmark)

    Løkke, H.; Damgaard, C.

    Report on Training Cource on GMO Risk Assessment in Silkeborg. -- DANCEE - Environmental Assistance to Eastern Europe. (NEPA) is DEPA - (National) Danish Environmental Protection Agency (Miljøstyrelsen). NFNA - The National Forest and Nature Agency (Skov- og Naturstyrelsen). BEF - Baltic Environm...

  15. Canada's Clean Air Act

    International Nuclear Information System (INIS)

    This paper provided an outline of Canada's Clean Air Act and examined some of the regulatory changes that will occur as a result of its implementation. The Act is being introduced to strengthen the legislative basis for taking action on reducing air pollution and GHGs, and will allow the government to regulate both indoor and outdoor air pollutants and GHGs. The Act will require the Ministers of the Environment and Health to establish national air quality objectives, as well as to monitor and report on their attainment. The Canadian Environmental Protection Act will be amended to enable the government to regulate the blending of fuels and their components. The Motor Vehicle Fuel Consumption Standards Act will also be amended to enhance the government's authority to regulate vehicle fuel efficiency. The Energy Efficiency Act will also be expanded to allow the government to set energy efficiency standards and labelling requirements for a wider range of consumer and commercial products. The Act will commit to short, medium and long-term industrial air pollution targets. Regulations will be proposed for emissions from industry; on-road and off-road vehicles and engines; and consumer and commercial products. It was concluded that the Government of Canada will continue to consult with provinces, territories, industries and Canadians to set and reach targets for the reduction of both indoor and outdoor air pollutants and GHG emissions. 6 figs

  16. The Experiment as Act

    DEFF Research Database (Denmark)

    Søndergaard, Morten

    identify and locate the experiments of POEX65 as acts; and to ask the questions: what constitutes those acts as experiments? and how do we possibly archive them? My purpose, then, is to define the methodologies to obtain the contours of a post-phenomenology of experimental artistic production in order to...... be able to analyse the phenomena found at POEX65. Here I will use the notion of the ‘ontological theatre’ (Pickering), which, according to Pickering, is acted out in experimental art productions. The experiment could thus be seen as an ‘agency-realism’ – as an ‘act’ of relations across the aesthetics...

  17. The Energy Act 1983

    International Nuclear Information System (INIS)

    Part II of This Act came into force on 1 September 1983 and is concerned with nuclear installations. Its main purpose is to amend the Nuclear Installations Act 1965 to give effect to the provisions of two Protocols amending the Paris Convention on nuclear third party liability and the Brussels Convention Supplementary to the Paris Convention respectively. The principal effect of these modifications is to increase the sums available to meet claims for nuclear damage. The United Kingdom is a Party to both Conventions and the provisions of the 1983 Act will enable it to ratify the Protocols. (NEA)

  18. Endangered Species Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The purpose of the Endangered Species Act (ESA) is to protect and recover imperiled species and the ecosystems upon which they depend. The U.S. Fish and Wildlife...

  19. Marine Pollution Prevention Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Marine Pollution Prevention Act of 2008 implements the International Convention for the Prevention of Pollution from Ships, including related Protocols (MARPOL)...

  20. Abandoned Shipwreck Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Abandoned Shipwreck Act of 1987 (ASA) affirms the authority of state governments to claim ownership to, protect, and manage abandoned shipwrecks on state...

  1. Energy Policy Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Energy Policy Act (EPA) addresses energy production in the United States, including: (1) energy efficiency; (2) renewable energy; (3) oil and gas; (4) coal; (5)...

  2. Clean Water Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Clean Water Act (CWA) establishes the basic structure for regulating discharges of pollutants into U.S. waters and regulating quality standards for surface...

  3. Affordable Care Act (ACA)

    Data.gov (United States)

    Social Security Administration — The Affordable Care Act (ACA) is a federal statute enacted with a goal of increasing the quality and affordability of health insurance. Through a web service, CMS...

  4. The CEO's second act.

    Science.gov (United States)

    Nadler, David A

    2007-01-01

    When a CEO leaves because of performance problems, the company typically recruits someone thought to be better equipped to fix what the departing executive couldn't--or wouldn't. The board places its confidence in the new person because of the present dilemma's similarity to some previous challenge that he or she dealt with successfully. But familiar problems are inevitably succeeded by less familiar ones, for which the specially selected CEO is not quite so qualified. More often than not, the experiences, skills, and temperament that yielded triumph in Act I turn out to be unequal to Act II's difficulties. In fact, the approaches that worked so brilliantly in Act I may be the very opposite of what is needed in Act II. The CEO has four choices: refuse to change, in which case he or she will be replaced; realize that the next act requires new skills and learn them; downsize or circumscribe his or her role to compensate for deficiencies; or line up a successor who is qualified to fill a role to which the incumbent's skills and interests are no longer suited. Hewlett-Packard's Carly Fiorina exemplifies the first alternative; Merrill Lynch's Stanley O'Neal the second; Google's Sergey Brin and Larry Page the third; and Quest Diagnostics' Ken Freeman the fourth. All but the first option are reasonable responses to the challenges presented in the second acts of most CEOs' tenures. And all but the first require a power of observation, a propensity for introspection, and a strain of humility that are rare in the ranks of the very people who need those qualities most. There are four essential steps executives can take to discern that they have entered new territory and to respond accordingly: recognition that their leadership style and approach are no longer working; acceptance of others' advice on why performance is faltering; analysis and understanding of the nature of the Act II shift; and, finally, decision and action. PMID:17286076

  5. Atomic Energy Act 1989

    International Nuclear Information System (INIS)

    This Act, which entered into force on 1 september 1989, contains a series of provisions dealing with different subjects: increase of public financing for British Nuclear Fuels plc, amendment of the Nuclear Installations Act 1965 regarding the powers of the Health and Safety Executive to recover expenses directly from nuclear operators and obligation of the UKAEA to take out insurance or other financial security to cover its liability and finally, measures to enable the UK to ratify the IAEA Convention on Assistance in Case of a Nuclear Accident or Radiological Emergency

  6. An Approach to Injective Acts over Monoids Based on Indecomposability

    OpenAIRE

    Sedaghatjoo, Mojtaba; Naghipoor, Mohammad Ali

    2016-01-01

    The main purpose of this paper is investigating classes of acts that are injective relative to all embeddings with indecomposable domains or codomains. We give some homological classifications of monoids in light of such kinds of injectivity. Our approach to indecomposable property provides a new characterization of right absolutely injective monoids as ones that all indecomposable acts are injective.

  7. Differentiation between Acting-Out and Non-Acting-Out Alcoholics with the Rorschach and Hand Test.

    Science.gov (United States)

    Haramis, Samuel L.; Wagner, Edwin E.

    1980-01-01

    Hand Test and Rorschach variables significantly differentiated two subgroups of aggressive and nonaggressive alcoholics. The aggressive group was characterized as hostile and impulsive. The predictor variables that emerged have practical value for recognizing the potential acting-out alcoholic. (Author)

  8. An Act of Colonization

    DEFF Research Database (Denmark)

    Rasmussen, Anders Bo

    and the United States signed an act on July 19, 1862, wherein the U.S. Navy agreed to unload “all negroes, mulattoes, or persons of color, delivered from on board vessels seized in the prosecution of the slave trade.” Yet, despite the two countries’ mutual interests in employing “laborers of African Extraction...

  9. ST–ACTS

    DEFF Research Database (Denmark)

    Gidofalvi, Gyozo; Pedersen, Torben Bach

    2006-01-01

    various geo–statistical data sources and intuitive principles, models the so far neglected aspects. ST–ACTS considers that (1) objects (representing mobile users) move from one spatio–temporal location to another with the objective of performing a certain activity at the latter location; (2) not all users...

  10. Acts of Research

    DEFF Research Database (Denmark)

    Nelund, Sidsel

    described as knowledge producers and exhibitions and art works as instances of knowledge production. Acts of Research: Knowledge Production in Contemporary Arts between Knowledge Economy and Critical Practices analyses this development. The academic discussion of knowledge production in the arts has taken...

  11. Draft environmental assessment for characterization of the Hanford Site pursuant to the Nuclear Waste Policy Act of 1982 (Public Law 97-425), Hanford Site, Richland, Benton County, Washington

    International Nuclear Information System (INIS)

    The Hanford Site is evaluated in this draft environmental assessment. The results of this evaluation are the basis for nominating the Hanford Site for site characterization leading to selection of the first repository site. The major conclusions are presented. 120 refs., 26 figs., 8 tabs

  12. On Retractable S-Acts

    Institute of Scientific and Technical Information of China (English)

    R.KHOSRAVI

    2012-01-01

    In this paper we introduce a class of right S-acts called retractable S-acts which are right S-acts with homomorphisms into their all subacts.We also give some classifications of monoids by comparing such acts with flatness properties.

  13. The Act of Walking

    DEFF Research Database (Denmark)

    Vestergaard, Maria Quvang Harck; Olesen, Mette; Helmer, Pernille Falborg

    2014-01-01

    ; Frumkin 2002). The term ‘walkability’ focuses on how the physical structures in the urban environment can promote walking, and how this potentially eases issues of public health and liveability in our cities (Krizek et al. 2009). However, the study of walking should not be reduced merely to the ‘hardware...... factors like lifestyle and life situation should be addressed in order to understand ‘walkability’ fully. The challenge is to approach issues linked to the ‘more-than representational’ (Thrift 2007; Vannini 2012) act of walking and thereby understand pedestrian behaviour in general, but also...... the individual perception of walking. This chapter exemplifies shows how a ‘more-than representational’ dimension can be added to the act of walking and open up for a more value-based discussion of walking, in this chapter exemplified in the Danish context. The chapter provides seven different cases of how...

  14. Radiological protection act, 1991

    International Nuclear Information System (INIS)

    This Act provides for the establishment of the Radiological Protection Institute of Ireland and dissolves An Bord Fuinnimh Nuicleigh (the Board), transferring its assets and liabilities to the Institute. It sets out a range of radiation protection measures to be taken by various Ministers in the event of a radiological emergency and gives effect at national level to the Assistance Convention, the Early Notification Convention and the Physical Protection Convention. The Institute is the competent Irish authority for the three Conventions. (NEA)

  15. Toxic Substances Control Act

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-15

    This Reference Book contains a current copy of the Toxic Substances Control Act and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  16. On Speech Act Theory

    Institute of Scientific and Technical Information of China (English)

    邓仁毅

    2009-01-01

    Speech act has developed from the work of linguistic philosophers and originates in Austin's observation and study. It was the particular search for the eonstative, utterances which describe something outside the text and can therefore be judged true or false that prompted John L. Austin to direct his attention to the distinction with so -called performa-tires. The two representative linguists are Aus-tin and Searle.

  17. Acting for Opera Singers

    OpenAIRE

    Hamilton, Jennifer

    2015-01-01

    As the majority of professional classical singers earn a significant part of their living in opera, it is vital that conservatoires and studios are able to provide fit-for-purpose education for these trainee artists. As opera productions today are increasingly influenced by the trends in cinema and live-streamed media, this study sought to identify and clarify the range and detail of acting and performance skills required of opera singers in this evolving professional environment. A significa...

  18. Williamson Act - The California Land Conservation Act of 1965

    Data.gov (United States)

    California Department of Resources — The California Land Conservation Act of 1965 - commonly referred to as the Williamson Act - is the State's primary program for the conservation of private land in...

  19. Frequent and potentially fatal envenoming by hump-nosed pit vipers (Hypnale hypnale and H. nepa) in Sri Lanka: lack of effective antivenom.

    Science.gov (United States)

    Ariaratnam, C A; Thuraisingam, V; Kularatne, S A M; Sheriff, M H R; Theakston, R D G; de Silva, A; Warrell, D A

    2008-11-01

    In a prospective study of snake bites involving 10 hospitals in Sri Lanka, 302 (35%) of 860 patients with bites by identified snakes proved to have been bitten by hump-nosed pit vipers (301 by Hypnale hypnale and 1 by H. nepa). Most victims were males aged between 11 years and 50 years who had been bitten on their feet or ankles while walking at night close to their homes. There was local swelling in 276 (91%) and local necrosis in 48 (16%). Eleven (4%) required amputation of fingers or toes and 12 (4%) received skin grafts. In 117 patients (39%) blood incoagulability was first detected between 15 min and 48 h after the bite, and in 116 of them this was present on admission to hospital. Spontaneous systemic bleeding was observed in 55 patients (18%). Acute renal failure developed in 10%, five of whom died to give an overall case fatality rate of 1.7%. Thus, bites by hump-nosed pit vipers can cause debilitating local and fatal systemic envenoming. In Sri Lanka and southwestern India where bites by these snakes are common, the only available antivenoms (raised against cobra, krait, Russell's viper and saw-scaled viper venoms) are ineffective and carry a high risk of reactions. PMID:18455743

  20. Affordable Care Act and Women

    Science.gov (United States)

    ... Privacy Policy FOIA Plain Writing Act No Fear Act Disclaimers Viewers & Players Assistant Secretary for Planning and Evaluation, Room 415F U.S. Department of Health and Human Services 200 Independence Avenue, SW Washington, D.C. ...

  1. 78 FR 73466 - Privacy Act

    Science.gov (United States)

    2013-12-06

    ... CORPORATION 22 CFR Part 707 Privacy Act AGENCY: Overseas Private Investment Corporation. ACTION: Notice of... (``OPIC'') Privacy Act (``PA'') regulations by making substantive and administrative changes. These... procedure, Privacy. For the reasons stated in the preamble the Overseas Private Investment...

  2. ACT/SAT College Survey.

    Science.gov (United States)

    Stafford, John E.

    1998-01-01

    Reports on findings of a survey designed to discover whether higher education institutions' admission standards accept SAT I or ACT and if there is preference for either, and whether ACT could be submitted in lieu of SAT II subject tests. Eighty-six percent of the reporting schools indicated no preference; 28 schools indicated that the ACT was an…

  3. Atomic Energy Authority Act 1954

    International Nuclear Information System (INIS)

    This Act provides for the setting up of an Atomic Energy Authority for the United Kingdom. It also makes provision for the Authority's composition, powers, duties, rights and liabilities, and may amend, as a consequence of the establishment of the Authority and in connection therewith, the Atomic Energy Act, 1946, the Radioactive Substances Act 1948 and other relevant enactments. (NEA)

  4. FCC and the Sunshine Act.

    Science.gov (United States)

    Weiss, Kenneth

    The Sunshine Act, designed to encourage open meetings to increase public understanding of the governmental decision-making process, went into effect in March 1977. A total of 50 agencies, including the Federal Communications Commission (FCC), are subject to the provisions of the Sunshine Act. The act lists 10 exemptions, any of which can result in…

  5. ACTS Rain Fade Compensation

    Science.gov (United States)

    Coney, Thom A.

    1996-01-01

    Performance status of the Adaptive Rain Fade Compensation includes: (1) The rain fade protocol is functional detecting fades, providing an additional 10 dB of margin and seamless transitions to and from coded operation; (2) The stabilization of the link margins and the optimization of rain fade decision thresholds has resulted in improved BER performance; (3) Characterization of the fade compensation algorithm is ongoing.

  6. A Balancing Act?

    DEFF Research Database (Denmark)

    Gerstlberger, Wolfgang; Stampe, Ian; Knudsen, Mette Præst

    the 2009 European Manufacturing Survey for the Danish sub-sample including 335 manufacturing firms. Through factor analysis, the paper confirms three main focus areas of new product development in relation to production facilities: efficiency considerations, market attention and greening of innovation....... Logistic regression analysis demonstrates that while market attention is important for new product development, green aspects of innovation and efficiency considerations for innovation are important for the energy efficiency of the production companies. Combining these models highlights that energy...... efficiency moderates the effect of market attention on new product development. The paper therefore concludes that product innovation and energy efficiency is a balancing act, focusing on one will have detrimental effects on the other! These findings point to the conclusion that researchers and practitioners...

  7. Full characterization of the Cu-, Zn-, and Cd-binding properties of CnMT1 and CnMT2, two metallothioneins of the pathogenic fungus Cryptococcus neoformans acting as virulence factors

    Science.gov (United States)

    Palacios, Òscar; Espart, Anna; Espín, Jordi; Ding, Chen; Thiele, Dennis J.; Atrian, Sílvia; Capdevila, Mercè

    2014-01-01

    We report here the full characterization of the metal binding abilities of CnMT1 and CnMT2, two Cryptococcus neoformans proteins recently identified as metallothioneins (MTs), which have been shown to perform a crucial role for the virulence and pathogenicity of this human-infecting fungus. In this work, we first performed a thorough in silico study of the CnMT1 and CnMT2 genes, cDNAs and corresponding encoded products. Subsequently, the Zn(II)-, Cd(II)- and Cu(I) binding abilities of both proteins were fully determined through the analysis of the metal-to-protein stoichiometries and the structural features (determined by ESI-MS, CD, ICP-AES and UV-vis spectroscopies) of the corresponding recombinant Zn-, Cd- and Cu-MT preparations synthesized in metal-enriched media. Finally, the analysis of the Zn/Cd and Zn/Cu replacement processes undertaken by the respective Zn-MT complexes when allowed to react with Cd(II) or Cu(I) aqueous solutions completed the analysis. Comprehensive consideration of all gathered results allow us to consider both isoforms as genuine copper-thioneins, and led to the identification of unprecedented Cu5-core clusters in MTs. CnMT1 and CnMT2 polypeptides appear as evolutionary related to the small fungal MTs, probably by ancient tandem-duplication events responding to a high selective pressure to chelate copper, and far from the properties of Zn- and Cd-thioneins. Finally, we propose a modular structure of the Cu-CnMT1 and Cu-CnMT2 complexes basically built on the three and five-fold presence of 7-Cys units, each one yielding a Cu5-core cluster. PMID:24317230

  8. JK '98: Acting responsibly

    International Nuclear Information System (INIS)

    For the first time, a paper delivered at the Annual Nuclear Conference was presented by two authors, the CEO of Bayernwerk AG, Dr. Otto Majewski, and the CEO of the Power Generation Division (KWU) of Siemens AG, Adolf Huettl, reflecting the operators' and the vendors' points of view about the present situation of nuclear power use in Germany and the need to maintain its share in the energy mix. The events associated with shipments of casks for radioactive waste have rekindled the debate about the responsibility of the peaceful use of nuclear power in the nuclear opposition camp. That debate needs to be put back on a factual basis. If no consensus could be achieved now about the use of nuclear power as a whole, at least consensus had to be reached about the future approach to spent fuel and waste management. From the outset, the nuclear industry has shown a high degree of responsibility, developing concepts of using uranium as an energy source in an economically viable and responsible way. It is showing responsibility also in making provision for the future. The safe and economically successful operation of today's nuclear power plants is an important reason for developing new reactor concepts. That development of new rector lines depends critically on the preservation and advancement of specialized knowledge. Know-how needs to be preserved and developed further not only for future nuclear power plants but also for the plants existing now, which still have service lives of several decades. Sustainable energy supply requires all sources of energy to be exploited, especially those which do not generate carbon dioxide. All the options currently known must be kept open and preserved, respectively, for coming generations. Acting responsibly means adding to the choices available. (orig.)

  9. [Euthanasia and medical act].

    Science.gov (United States)

    2011-05-01

    Right to life -as the prohibition of intentionally and arbitrarily taking life, even with authorization of the concerned one- is an internationally recognized right. In many countries, debate regarding euthanasia is more centered in its convenience, social acceptability and how it is regulated, than in its substantial legitimacy. Some argue that euthanasia should be included as part of clinical practice of health professionals, grounded on individual's autonomy claims-everyone having the liberty to choose how to live and how to die. Against this, others sustain that life has a higher value than autonomy, exercising autonomy without respecting the right to life would become a serious moral and social problem. Likewise, euthanasia supporters some-times claim a 'right to live with dignity', which must be understood as a personal obligation, referred more to the ethical than to the strictly legal sphere. In countries where it is already legalized, euthanasia practice has extended to cases where it is not the patient who requests this but the family or some healthcare professional, or even the legal system-when they think that the patient is living in a condition which is not worthy to live. Generalization of euthanasia possibly will end in affecting those who need more care, such as elder, chronically ill or dying people, damaging severely personal basic rights. Nature, purpose and tradition of medicine rule out the practice of euthanasia, which ought not be considered a medical act or legitimately compulsory for physicians. Today's medicine counts with effective treatments for pain and suffering, such as palliative care, including sedative therapy, which best preserves persons dignity and keeps safe the ethos of the medical profession.

  10. The Price-Anderson Act

    International Nuclear Information System (INIS)

    The Price-Anderson Act establishes nuclear liability law in the United States. First passed in 1957, it has influenced other nuclear liability legislation around the world. The insurer response the nuclear accident at Three Mile Island in 1979 demonstrates the application of the Act in a real life situation. The Price-Anderson Act is scheduled to be renewed in 2002, and the future use of commercial nuclear power in tge United States will be influenced by this renewal. (author)

  11. Atomic Energy Authority Act 1971

    International Nuclear Information System (INIS)

    This Act provides for the transfer of property, rights, liabilities and obligations of parts of the undertaking of the United Kingdom Atomic Energy Autority, to two new Compagnies set up for this purpose: the Bristish Nuclear Fuels Limited, and the Radiochemical Centre Limited. Patents licences and registered designs owned by the Autority at the time of the transfer are not included therein. The Act also includes amendments to the Nuclear Installations Act 1965, notably as regards permits to operate granted to a body corporate. Finally, the Schedule to this Act lays down a certain number of provisions relating to security and the preservation of secrets. (NEA)

  12. 75 FR 63703 - Privacy Act of 1974; Privacy Act Regulation

    Science.gov (United States)

    2010-10-18

    ... Federal Register, 73 FR 25594, May 7, 2008. The proposed amendments: (1) Waived all copying fees in..., 73 FR 54595, September 22, 2008, certain portions of BGFRS-37 (Electronic Applications) may be exempt... CFR Part 261a Privacy Act of 1974; Privacy Act Regulation AGENCY: Board of Governors of the...

  13. Characterization of the Hanford Site and environs

    Energy Technology Data Exchange (ETDEWEB)

    Cushing, C.E. (ed.)

    1991-03-01

    The US Department of Energy (DOE) proposes to site, construct, and operate a new production reactor (NPR) intended to produce materials for the US nuclear weapons program. The DOE has determined that this proposed action constitutes an action that may significantly affect the quality of the human environment; therefore, the DOE is preparing an environmental impact statement (EIS) to assess the potential impacts of the proposed action and reasonable alternatives on the human and natural environment. The NPR-EIS is being prepared in accordance with Section 102(2)(C) of the National Environmental Policy Act of 1969 (NEPA), as implemented in regulations (40 CFR 1500--1508) promulgated by the Council on Environmental Quality (CEQ). Information on the potentially affected environment at the Hanford Site and its environs was provided to ANL by PNL in various submissions during CY-1989, and some of that information was consolidated into this report, which is considered to be supporting documentation for the NPR-EIS. 93 refs., 35 figs., 46 tabs.

  14. Nuclear Material (Offences) Act 1983

    International Nuclear Information System (INIS)

    The main purpose of this Act is to enable the United Kingdom to ratify the Convention on the Physical Protection of Nuclear Material which opened for signature at Vienne and New York on 3 March 1980. The Act extends throughout the United Kingdom. (NEA)

  15. Atomic Energy Commission Act, 1963

    International Nuclear Information System (INIS)

    Promulgated in 1963, the Atomic Energy Commission Act (204) established and vested in the Ghana Atomic Energy Commission the sole responsibility for all matters relating to the peaceful uses of atomic energy in the country. Embodied in the Act are provisions relating to the powers, duties, rights and liabilities of the Commission. (EAA)

  16. Acting to let someone die.

    Science.gov (United States)

    McGee, Andrew

    2015-02-01

    This paper examines the recent prominent view in medical ethics that withdrawing life-sustaining treatment (LST) is an act of killing. I trace this view to the rejection of the traditional claim that withdrawing LST is an omission rather than an act. Although that traditional claim is not as problematic as this recent prominent view suggests, my main claim is that even if we accepted that withdrawing LST should be classified as an act rather than as an omission, it could still be classified as letting die rather than killing. Even though omissions are contrasted with acts, letting die need not be, for one can let die by means of acts. The remainder of the paper is devoted to establishing this claim and addresses certain objections to it.

  17. Act local, think global

    International Nuclear Information System (INIS)

    Tip O'Neill, one of the grand old men of modem US politics, once famously remarked that all politics is local. Like most politicians who succeed on the national stage - and not just in the US - it was a truth he never lost sight of. What is true for politicians is equally true in the communications business. We may increasingly live in a global village, but successful companies - even multi-nationals - forget the importance of local and regional public relations at their peril. Think of Douglas Ivester, the CEO of Coca-Cola at the time of the 1999 Belgian contamination scandal, who allegedly reacted to first reports of the crisis by asking: 'Where the hell is Belgium?' A more appropriate question today - several years after Coke's share price toppled and the CEO was unceremoniously sacked - might be: 'Who the hell is Douglas Nester?' But - to adapt another famous phrase - the fact that communications (and marketing) professionals still need to 'act local' as much as ever before should not blind us to the growing need to 'think global'. In the nuclear industry, as in the world economy generally, increasing global integration is a reality, as are the international nature of the news media and the increasingly global nature of the anti-nuclear pressure groups. Indeed, it was the growing need for a truly global information network to counter these trends, by increasing the overall speed and accuracy of the worldwide nuclear information flow, that led the nuclear community to establish NucNet in 1991. So where exactly is the line between local and regional nuclear communications on the one hand, and global communications on the other? Is there one spin for a regional audience, and another for a global audience? This presentation proposes some guiding principles, by examining the response of nuclear communicators world-wide to the new communications agenda imposed in the wake of the September 11th suicide attacks in the US. NucNet President Doug McRoberts and Executive

  18. Endangered Species Act Critical Habitat

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Critical habitat (CH) is designated for the survival and recovery of species listed as threatened or endangered under the Endangered Species Act (ESA). Critical...

  19. 7 CFR 33.1 - Act.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Act. 33.1 Section 33.1 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and...

  20. Act 7 Ask for Commitment

    Institute of Scientific and Technical Information of China (English)

    Duane Sparks from KMG

    2008-01-01

    <正>"I’ll bite.How does Action Selling define an objection?""Action Selling defines an objection as a customer’s response to an unasked question,"Joe said."Every objection you’ll ever hear will relate to one of the customer’s five buying decisions.And all of the objections you hear could have been uncovered during Act 3 instead of in Act 7.""Come again?"Matt asked."This is important,so listen up,"Joe said."If you had followed the"Ask the Best Questions Map"carefully in Act 3 to determine the needs,issues,competition,budget,buying influences,and time frame,then objections you hear at the end of

  1. Resource Conservation and Recovery Act (RCRA)

    International Nuclear Information System (INIS)

    This Resource Conservation and Recovery Act (RCRA) Facility Investigation Program Plan has been developed to provide a framework for the completion of RCRA Facility Investigations (RFI) at identified units on the Savannah Rive Site (SRS) facility. As such, the RFI Program Plan provides: technical guidance for all work to be performed, managerial control, a practical, scientific approach. The purpose of this Overview is to demonstrate how the basic RFI Program Plan elements (technical, management, and approach) are interwoven to provide a practical and workable plan. The goal of the RFI Program Plan is to provide a systematic, uniform approach for performance and reporting. In addition, the RFI Program Plan has been developed to be specific to the SRS facility and to adhere to the Environmental Protection Agency (EPA) RFI guidance received as part of the SRS. The US EPA publication ''Characterization of Hazardous Waste Sites'' has been liberally adapted for use in this RFI Program Plan

  2. Modification as a propositional act

    DEFF Research Database (Denmark)

    Rijkhoff, Jan

    2014-01-01

    material in a Discourse Act has been largely ignored. This chapter argues (i) that modifying is no less actional than predicating or referring in the process of verbal communication and (ii) that the modifying function of linguistic material should be specified at the highest level of representation...

  3. 76 FR 59073 - Privacy Act

    Science.gov (United States)

    2011-09-23

    ...) and (p) to read as follows: Sec. 1901.02 Definitions. * * * * * (o) Director of Central Intelligence... From the Federal Register Online via the Government Publishing Office CENTRAL INTELLIGENCE AGENCY 32 CFR Part 1901 Privacy Act AGENCY: Central Intelligence Agency. ACTION: Proposed rule....

  4. Sport supporting act: terminology issues

    Directory of Open Access Journals (Sweden)

    Petr Vlček

    2013-01-01

    Full Text Available BACKGROUND: The text deals with terminology issues from an interdisciplinary point of view. It is based on two different disciplines, law and kinanthropology, in an area of their overlap. AIM: The aim of the author is to point out some possible legislative problems, which could arise due to the current reading of the sport supporting act (Act no. 115/2001. The second aim of the author is to contribute to the discussion of kinantropologists (possibly also the educational researchers and lawyers and to stress the importance of the systematic approach to terminology formulation. METHODS: The author uses the method of language interpretation. We also use the basic analytical methods, induction and deduction, while we stress the systematic approach to the term formulation. RESULTS: The analysis of the sport supporting act terminology shows some specific legislative problems, which could arise due to the definition of sport in the sport supporting act. The author discusses a possible alternative solution. CONCLUSION: According to the opinion of the author, clear, obvious and unified terminology of kinantropologists as specialists in their discipline should represent a source, from which other sciences could derive their terminology. Defined and inexpert terminology used in other disciplines should not be used as an argument for its adopting in kinanthropology.

  5. The Ontogenesis of Speech Acts

    Science.gov (United States)

    Bruner, Jerome S.

    1975-01-01

    A speech act approach to the transition from pre-linguistic to linguistic communication is adopted in order to consider language in relation to behavior and to allow for an emphasis on the use, rather than the form, of language. A pilot study of mothers and infants is discussed. (Author/RM)

  6. Dumping at Sea Act 1974

    International Nuclear Information System (INIS)

    This Act enables the United Kingdom Government to ratify both the Oslo Convention of 1972 for the Prevention of Marine Pollution by Dumping from Ships and Aircraft and the London Convention of 1972 on the Prevention of Marine Pollution by Dumping of Wastes and Other Matter. (NEA)

  7. Personal Information as Communicative Acts

    DEFF Research Database (Denmark)

    Mai, Jens-Erik

    2016-01-01

    as communicative acts. The paper suggests a reconceptualization of informational privacy from having its focus on controlling, limiting, and restricting access to material carriers of information to a focus on a regulation of the use, analysis, and interpretation of personal information....

  8. Paraconsistent semantics of speech acts

    NARCIS (Netherlands)

    Dunin-Kȩplicz, Barbara; Strachocka, Alina; Szałas, Andrzej; Verbrugge, Rineke

    2015-01-01

    This paper discusses an implementation of four speech acts: assert, concede, request and challenge in a paraconsistent framework. A natural four-valued model of interaction yields multiple new cognitive situations. They are analyzed in the context of communicative relations, which partially replace

  9. 78 FR 46256 - Privacy Act

    Science.gov (United States)

    2013-07-31

    ... From the Federal Register Online via the Government Publishing Office FEDERAL ELECTION COMMISSION 11 CFR Part 1 Privacy Act CFR Correction In Title 11 of the Code of Federal Regulations, revised as of January 1, 2012, on page 5, in Sec. 1.2, the words ``95 and 96 of the Internal Revenue Code...

  10. Against acts of nuclear terrorism

    International Nuclear Information System (INIS)

    The Act on the International Convention of the United Nations of April 13, 2005 on Combating Acts of Nuclear Terrorism was promulgated in the German Federal Gazette and entered into force one day later. The Convention expresses the deep concern about the worldwide escalation of all kinds and manifestations of acts of terrorism. What was true in April 2005 (the year the UN convention was adopted) is even more true today. At the same time, however, the Convention recognizes the right of all nations to develop and use nuclear power for peaceful purposes, acknowledging their justified interest in the possible benefits of the peaceful uses of nuclear power. As the Convention was signed in German still during the term of office of the Red-Green government, this passage is a remarkable acceptance of the realities of the world and past peaceful uses of nuclear power in Germany. Whether or not the convention will become an effective instrument to be used against acts of nuclear terrorism and threats depends on its entering into force after deposition of 22 ratification documents, and on as many states as possible acceding to it. Irrespective of these aspects, action in the spirit of the Convention should be taken now, criminal law should be adapted, and international cooperation should be improved and strengthened. (orig.)

  11. Impacts Analyses Supporting the National Environmental Policy Act Environmental Assessment for the Resumption of Transient Testing Program

    Energy Technology Data Exchange (ETDEWEB)

    Annette L. Schafer; Lloyd C. Brown; David C. Carathers; Boyd D. Christensen; James J. Dahl; Mark L. Miller; Cathy Ottinger Farnum; Steven Peterson; A. Jeffrey Sondrup; Peter V. Subaiya; Daniel M. Wachs; Ruth F. Weiner

    2013-11-01

    Environmental and health impacts are presented for activities associated with transient testing of nuclear fuel and material using two candidate test reactors. Transient testing involves irradiation of nuclear fuel or materials for short time-periods under high neutron flux rates. The transient testing process includes transportation of nuclear fuel or materials inside a robust shipping cask to a hot cell, removal from the shipping cask, pre-irradiation examination of the nuclear materials, assembly of an experiment assembly, transportation of the experiment assembly to the test reactor, irradiation in the test reactor, transport back to the hot cell, and post-irradiation examination of the nuclear fuel or material. The potential for environmental or health consequences during the transportation, examination, and irradiation actions are assessed for normal operations, off-normal (accident) scenarios, and transportation. Impacts to the environment (air, soil, and groundwater), are assessed during each phase of the transient testing process. This report documents the evaluation of potential consequences to the general public. This document supports the Environmental Assessment (EA) required by the U.S. National Environmental Policy Act (NEPA) (42 USC Subsection 4321 et seq.).

  12. 34 CFR 300.4 - Act.

    Science.gov (United States)

    2010-07-01

    ... Definitions Used in This Part § 300.4 Act. Act means the Individuals with Disabilities Education Act, as... 34 Education 2 2010-07-01 2010-07-01 false Act. 300.4 Section 300.4 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE...

  13. 7 CFR 35.1 - Act.

    Science.gov (United States)

    2010-01-01

    ... Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS EXPORT GRAPES AND PLUMS Definitions § 35.1 Act. Act or Export Grape and Plum Act means “An Act to promote the foreign trade of...

  14. Clean Air Act. Revision 5

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-15

    This Reference Book contains a current copy of the Clean Air Act, as amended, and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. This Reference Book has been completely revised and is current through February 15, 1994.

  15. SCADA Application for ACTS Technology

    Science.gov (United States)

    Fairbanks, Barry

    1992-01-01

    The results of a system level study done by Hughes Network Systems for NASA are presented. For the supervisory control and data acquisition (SCADA) application, use of Ka-band spot beam satellite technology associated with NASA's Advanced Communication Technology Satellite (ACTS) offers a reduction in Earth station antenna size and transmitter power that may translate into lower system costs. The approaches taken to determine commercial potential of the system are described.

  16. Federal Facilities Compliance Act, Conceptual Site Treatment Plan. Part 1

    International Nuclear Information System (INIS)

    This Conceptual Site Treatment Plan was prepared by Ames Laboratory to meet the requirements of the Federal Facilities Compliance Act. Topics discussed in this document include: general discussion of the plan, including the purpose and scope; technical aspects of preparing plans, including the rationale behind the treatability groupings and a discussion of characterization issues; treatment technology needs and treatment options for specific waste streams; low-level mixed waste options; TRU waste options; and future waste generation from restoration activities

  17. Federal Facilities Compliance Act, Conceptual Site Treatment Plan. Part 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-10-29

    This Conceptual Site Treatment Plan was prepared by Ames Laboratory to meet the requirements of the Federal Facilities Compliance Act. Topics discussed in this document include: general discussion of the plan, including the purpose and scope; technical aspects of preparing plans, including the rationale behind the treatability groupings and a discussion of characterization issues; treatment technology needs and treatment options for specific waste streams; low-level mixed waste options; TRU waste options; and future waste generation from restoration activities.

  18. 77 FR 5793 - Beaches Environmental Assessment and Coastal Health Act; Availability of BEACH Act Grants

    Science.gov (United States)

    2012-02-06

    ... AGENCY Beaches Environmental Assessment and Coastal Health Act; Availability of BEACH Act Grants AGENCY... Water Act (CWA) as amended by the Beaches Environmental Assessment and Coastal Health (BEACH) Act.... EPA encourages coastal and Great Lakes states and tribes that have received BEACH Act grants in...

  19. Acting, Intending, and Artificial Intelligence

    OpenAIRE

    Hauser, L.

    1994-01-01

    Hauser considers John Searle's attempt to distinguish acts from movements. On Searle's account, the difference between me raising my arm and my arm's just going up (e.g., if you forcibly raise it), is the causal involvement of my intention to raise my arm in the former, but not the latter, case. Yet, we distinguish a similar difference between a robot's raising its arm and its robot arm just going up (e.g., if you manually raise it). Either robots are rightly credited with intentions or it's ...

  20. Pseudo force acting between bodies

    Science.gov (United States)

    Baruah, Abhinav Ray; Deva, Anish; Sarma, Arun

    It has been shown that a non-contact force acts between two macroscopic physical objects held close together, which is not associated with the gravitational and electrostatic force. An experiment was conducted with objects of different mass, material and geometry to find the magnitude and properties of this apparent or pseudo force. The order of magnitude was found to be 10-5 and it remained constant for all types of objects while only the coefficient increased as the distance between the objects reduced. It only started acting at small distances and failed to make a body move if it experienced static friction from any contact surface. The nature of the force was found to be attractive as well as repulsive. Due to gravitation being a solely attractive force, it was eliminated as a possible reason for the pseudo force. The experiment was performed twice, once by grounding the apparatus and then again without grounding. The order of the force remained the same for both cases. As the test objects were held by hand, they were grounded through the human body. Also, none of the objects used were in contact with each other for the duration of this work, preventing any contact electrification. Due to these factors, the force was not considered electrostatic in nature.

  1. 7 CFR 1207.302 - Act.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.302 Act. Act means the Potato Research...

  2. Site characterization plan:

    International Nuclear Information System (INIS)

    The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in acordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for a repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and eveloping a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing prinicples, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed. 880 refs., 130 figs., 25 tabs

  3. Site characterization plan:

    International Nuclear Information System (INIS)

    The Yucca Mountain site in Nevada is one of three candidate sites for the first geologic repository for radioactive waste. On May 28, 1986, it was recommended for detailed study in a program of site characterization. This site characterization plan (SCP) has been prepared in accordance with the requirements of the Nuclear Waste Policy Act to summarize the information collected to date about the geologic conditions at the site;to describe the conceptual designs for the repository and the waste package;and to present the plans for obtaining the geologic information necessary to demonstrate the suitability of the site for repository, to design the repository and the waste package, to prepare an environmental impact statement, and to obtain from the US Nuclear Regulatory Commission (NRC) an authorization to construct the repository. This introduction begins with a brief section on the process for siting and developing a repository, followed by a discussion of the pertinent legislation and regulations. A description of site characterization is presented next;it describes the facilities to be constructed for the site characterization program and explains the principal activities to be conducted during the program. Finally, the purpose, content, organizing principles, and organization of this site characterization plan are outlined, and compliance with applicable regulations is discussed

  4. 7 CFR 1205.10 - Act.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1205.10 Section 1205.10 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND... for Conduct of Sign-up Period Definitions § 1205.10 Act. The term Act means the Cotton Research...

  5. 7 CFR 1219.1 - Act.

    Science.gov (United States)

    2010-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.1 Act. Act means the Hass Avocado Promotion, Research, and Information Act of 2000, Public Law 106-387, 7 U.S.C....

  6. 7 CFR 1215.1 - Act.

    Science.gov (United States)

    2010-01-01

    ... ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Definitions § 1215.1 Act. Act means the Popcorn Promotion, Research, and Consumer Information Act of 1995, Subtitle E of Title V of...

  7. Learning activism, acting with phronesis

    Science.gov (United States)

    Lee, Yew-Jin

    2015-12-01

    The article "Socio-political development of private school children mobilising for disadvantaged others" by Darren Hoeg, Natalie Lemelin, and Lawrence Bencze described a language-learning curriculum that drew on elements of Socioscientific issues and Science, Technology, Society and Environment. Results showed that with a number of enabling factors acting in concert, learning about and engagement in practical action for social justice and equity are possible. An alternative but highly compatible framework is now introduced—phronetic social research—as an action-oriented, wisdom-seeking research stance for the social sciences. By so doing, it is hoped that forms of phronetic social research can gain wider currency among those that promote activism as one of many valued outcomes of an education in science.

  8. Personal Information as Communicative Acts

    DEFF Research Database (Denmark)

    Mai, Jens-Erik

    2016-01-01

    communicative acts. The paper suggests a reconceptualization of informational privacy from having its focus on controlling, limiting, and restricting access to material carriers of information to a focus on a regulation of the use, analysis, and interpretation of personal information.......The paper extends previous accounts of informational privacy as a contextual notion. Where previous accounts have focused on interpretations of the privacy context itself as being contextual and open for negotiation and interpretation, this paper extends those analyses and shows that personal...... information itself is in fact best understood as contextual and situational—and as such open for interpretation. The paper reviews the notion of information as it has been applied in informational privacy and philosophy of information, and suggests that personal information ought to be regarded as...

  9. Acting Antarctica: science on stage

    Science.gov (United States)

    Ciceri, Piera; Tizzoni, Paola; Pierro, Luigia

    2016-04-01

    Key-words: Polar science, Earth science, Theatre, Hands on activities The legendary Antarctic Expedition of sir E. Shackleton and his crew of 27 aboard the Endurance (1914/16) trapped in the Antarctic ice has become the starting point to learn about Polar Science and Climate Change. While the students were involved into this incredible adventure by the astonishing images of the Australian photographer Frank Hurley (who joined the crew), they discovered the world in which this story happened. Students were then involved in hands-on activities and role plays and have become the writers of the play "Uomini a scienza ai confini del mondo". They act the story of Shackelton's expedition and they tell at the same time to the audience about ice pack, ice cores and their role in understanding the past of the climate, physical and geographical characteristic of polar regions, thermal phenomena related to adaptations of polar animals, solar radiation at different latitude, day/night duration. The theater was the place to "stage" some scientific experiments and to explain the current research carried out in polar regions and their importance in climate change studies and to stress some similarities between Antarctica and space. The project was carried out from teachers of science, letters and geography and was born in collaboration with the "Piccolo Teatro di Milano" and the association "Science Under 18" with the support of a professional actor and director and was played for other schools at "EXPO 2015" in Milano (Italy). In our opinion drama activities improve reading comprehension, and both verbal and non-verbal communication skills. To be able to write and to act, students need a deep understanding of contents. Arts, including theatre, are a good key to involve emotionally students. To have an audience different from their own teachers and classmates offers a real task and the opportunity to play and let grow real skills.

  10. Long-acting contraceptive options.

    Science.gov (United States)

    Kaunitz, A M

    1996-01-01

    Long-acting contraceptive methods are appropriate choices for women who prefer the convenience and high contraceptive efficacy of methods not requiring frequent compliance, and women for whom contraceptive doses of estrogen are either medically contraindicated or associated with persistent intolerable side effects. Annual pregnancy rates for the three methods described below are less than 1 per 100 woman-years. As currently formulated, levonorgestrel implants (Norplant) consist of six 34 x 2.4 mm soft plastic implants, each filled with 36 mg of crystalline levonorgestrel. Irregular and often persistent menstrual bleeding and spotting constitute the most important side effects experienced by and leading to method discontinuation in implant users. Implant removal is technically more difficult and time-consuming than insertion. Depot-medroxyprogesterone acetate (DMPA or Depo-Provera) is injected as an aqueous suspension of microcrystals. Intramuscular injection of 150 mg of DMPA results in more than 3 months of contraception. Irregular bleeding and spotting followed by amenorrhea, constitute the most importance side effects experienced by DMPA users. Because DMPA use can result in prolonged (but not permanent) infertility, DMPA is not an optimum contraceptive choice for women who may want to conceive in the next one or two years. The Copper T380A intrauterine device (IUD) provides reversible contraception for up to 10 years. IUDs act as contraceptives, not early abortafacients. Recent epidemiologic data indicate that long-term IUD use does not increase the occurrence of pelvic inflammatory disease. Heavier menstrual flow and cramps constitute the main side effects experienced by women using the copper IUD. Intrauterine device insertion and removal are accomplished during brief office-based procedures. PMID:8829701

  11. 76 FR 64112 - Privacy Act of 1974; Privacy Act System of Records Appendices

    Science.gov (United States)

    2011-10-17

    ... SPACE ADMINISTRATION Privacy Act of 1974; Privacy Act System of Records Appendices AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Revisions of NASA Appendices to Privacy Act System of... publishes with the Agency's systems of records under the Privacy Act of 1974. This notice publishes...

  12. 78 FR 77719 - Privacy Act of 1974; Privacy Act System of Records

    Science.gov (United States)

    2013-12-24

    ... SPACE ADMINISTRATION Privacy Act of 1974; Privacy Act System of Records AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of Privacy Act system of records. SUMMARY: Pursuant to the provisions of the Privacy Act of 1974 (5 U.S.C. 552a), the National Aeronautics and Space Administration...

  13. 76 FR 64114 - Privacy Act of 1974; Privacy Act System of Records

    Science.gov (United States)

    2011-10-17

    ... SPACE ADMINISTRATION Privacy Act of 1974; Privacy Act System of Records AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of proposed revisions to an existing Privacy Act system of records. SUMMARY: Pursuant to the provisions of the Privacy Act of 1974 (5 U.S.C. 552a), the...

  14. 12 CFR 741.214 - Report of crime or catastrophic act and Bank Secrecy Act compliance.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Report of crime or catastrophic act and Bank Secrecy Act compliance. 741.214 Section 741.214 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION... Unions § 741.214 Report of crime or catastrophic act and Bank Secrecy Act compliance. Any credit...

  15. The Problem of Agency; How Humans Act, How Machines Act

    DEFF Research Database (Denmark)

    Rose, Jeremy; Jones, M.; Truex, D.

    2003-01-01

    put forward based on Giddens’ structuration theory, and, more recently, from actor network theory. The two theories, however, may be seen to adopt rather different, and potentially incompatible, views of agency (action). Thus, structuration theory sees agency as a uniquely human property, whereas...... the principle of general symmetry in actor network theory implies that machines may also be actors (agents). This rather fundamental disagreement may be characterized as the problem of agency. At the empirical level the problem of agency was played out in a Canadian telecoms company adopting an ERP system....... Was it the mangers and unions (the human agents) that were determining the trajectory of the organization, or did the ERP system also play a role? This paper argues that neither structuration theory or actor network theory offers a particularly convincing account of the interplay of human and machine agency...

  16. Close Packing of Listeria monocytogenes ActA, a Natively Unfolded Protein, Enhances F-actin Assembly without Dimerization*

    OpenAIRE

    Footer, Matthew J.; Lyo, John K; Theriot, Julie A.

    2008-01-01

    Studies of the biochemistry of Listeria monocytogenes virulence protein ActA have typically focused on the behavior of bacteria in complex systems or on the characterization of the protein after expression and purification. Although prior in vivo work has proposed that ActA forms dimers on the surface of L. monocytogenes, dimerization has not been demonstrated in vitro, and little consideration has been given to the surface environment where ActA performs its pivotal r...

  17. THE LANGUAGE OF LEGISLATIVE ACTS

    Directory of Open Access Journals (Sweden)

    Галина Викторовна Томсон

    2013-07-01

    Full Text Available Teaching language for specific purposes is the basis of the MGIMO Bachelors’ and Masters’ language education. However, it is experts on language and teaching rather than specialists in the sphere of law that are engaged in this work. The author of this article shares her experience of mastering a new specialization and applying her linguistic knowledge to it.It is creating educational resources that requires not only careful selection of authentic texts, defining specialized lexical base, but also viewing these texts as a complex syntactic whole, possessing its own structure and constituting a language unit that can be modeled. Linguistic perception of specialized texts facilitates the creation of practice-oriented educational resources, the application of which results in university graduates’ ability to use the language of their profession properly.The main conclusion from the results presented in this research shows that the dependent clauses act as the limiting ones. This allows you to add unambiguity and clarity to professional language. Simultaneous accesses to the world of reality and the world of language explains its primary role in verbal and cogitative human activity and puts the sentence as the basic unit of speech in the center of the "language - thinking" system, relating thought and language structures in the overall implementation of the communicative function of language.DOI: http://dx.doi.org/10.12731/2218-7405-2013-6-6

  18. Professionalism under the Legal Services Act 2007

    OpenAIRE

    Boon, A.

    2010-01-01

    The Legal Services Act 2007 represents an ambitious attempt to reconcile consumerism and professionalism. The Act created a Legal Services Board to oversee the regulation of the legal services market in England and Wales. The Board was also placed under a duty to promote consumer interests and to encourage an independent, strong, diverse and effective legal profession and to promote professional principles. The article examines the actual and prospective impacts of the Act on the legal profes...

  19. Altered glycosylation profile of purified plasma ACT from Alzheimer’s disease

    Directory of Open Access Journals (Sweden)

    Carbone Ilaria

    2010-12-01

    Full Text Available Abstract Background Alzheimer’s disease (AD is one of the most frequent cause of neurodegenerative disorder in the elderly. Inflammation has been implicated in brain degenerative processes and peripheral markers of brain AD related impairment would be useful. Plasma levels of alpha-1-antichymotrypsin (ACT, an acute phase protein and a secondary component of amyloid plaques, are often increased in AD patients and high blood ACT levels correlate with progressive cognitive deterioration. During inflammatory responses changes in the micro-heterogeneity of ACT sugar chains have been described. Methods N-Glycanase digestion from Flavobacterium meningosepticum (PNGase F was performed on both native and denatured purified ACT condition and resolved to Western blot with the purpose to revealed the ACT de-glycosylation pattern. Further characterization of the ACT glycan profile was obtained by a glycoarray; each lectin group in the assay specifically recognizes one or two glycans/epitopes. Lectin-bound ACT produced a glyco-fingerprint and mayor differences between AD and controls samples were assessed by a specific algorithms. Results Western blot analysis of purified ACT after PNGase F treatment and analysis of sugar composition of ACT showed significantly difference in “glyco-fingerprints” patterns from controls (CTR and AD; ACT from AD showing significantly reduced levels of sialic acid. A difference in terminal GlcNac residues appeared to be related with progressive cognitive deterioration. Conclusions Low content of terminal GlcNac and sialic acid in peripheral ACT in AD patients suggests that a different pattern of glycosylation might be a marker of brain inflammation. Moreover ACT glycosylation analysis could be used to predict AD clinical progression and used in clinical trials as surrogate marker of clinical efficacy.

  20. BBG 2008 Freedom of Information Act Report

    Data.gov (United States)

    Broadcasting Board of Governors — The Broadcasting Board of Governors' annual Freedom of Information Act (FOIA) report includes detailed statistics on the number and disposition of FOIA requests,...

  1. Resource Conservation and Recovery Act Information (RCRAInfo)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Resource Conservation and Recovery Act Information (RCRAInfo) system contains information reported to the state environmental programs on activities and cleanup...

  2. From Rehearsed Monologue to Spontaneous Acting

    Science.gov (United States)

    Niedzielski, Henri

    1972-01-01

    Suggests that the effective prerequisites for teaching methods courses are cheerleading, modern dance, and dramatics. Follows acting methods and mental attitudes of Polish director, Jerzy Grotowski. (DS)

  3. The Education Act (Ontario) 1980: A Review.

    Science.gov (United States)

    Hodder, C. J.

    1984-01-01

    Ontario has provided special education legislation through the Education Amendment Act, 1980. Issues related to teacher preparation for special education and program planning and implementation are reviewed. (DF)

  4. Motivating administrative acts - doctrinal and jurisprudential issues

    Directory of Open Access Journals (Sweden)

    Mihai Cristian APOSTOLACHE

    2014-06-01

    Full Text Available The article approaches the topic of administrative acts motivation, analyzed from the doctrinal and jurisprudential perspective. If at first, motivation was considered merely a formal condition of the administrative act, as a result of the national and European, doctrinal and jurisprudential evolution, motivation is now regarded as one of the most important conditions of validity for the administrative act. Motivating administrative acts represents also a manifestation of the right to information, sealed by the Romanian Constitution, and a dimension of the right to a good administration, as stipulated in the Charter of Fundamental Rights of the European Union.

  5. BBG 2009 Freedom of Information Act Repot

    Data.gov (United States)

    Broadcasting Board of Governors — The Broadcasting Board of Governors' annual Freedom of Information Act (FOIA) report includes detailed statistics on the number and disposition of FOIA requests,...

  6. ReACT Methodology Proof of Concept Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Bri Rolston; Sarah Freeman

    2014-03-01

    The Department of Energy’s Office of Electricity Delivery and Energy Reliability (DOE-OE) funded INL Researchers to evaluate a novel process for assessing and mitigating cyber security risks. The proof of concept level of the method was tested in an industry environment. This case study, plus additional case studies will support the further development of the method into a tool to assist industry in securing their critical networks. This report provides an understanding of the process developed in the Response Analysis and Characterization Tool (ReACT) project. This report concludes with lessons learned and a roadmap for final development of these tools for use by industry.

  7. 3 CFR - Freedom of Information Act

    Science.gov (United States)

    2010-01-01

    ... by their Government. Disclosure should be timely. I direct the Attorney General to issue new... 3 The President 1 2010-01-01 2010-01-01 false Freedom of Information Act Presidential Documents Other Presidential Documents Memorandum of January 21, 2009 Freedom of Information Act Memorandum...

  8. 75 FR 12584 - Sunshine Act; Public Hearing

    Science.gov (United States)

    2010-03-16

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Sunshine Act; Public Hearing March 17, 2010. OPIC's Sunshine Act notice of its Public Hearing in... record; therefore, OPIC's public hearing scheduled for 3 p.m., March 17, 2010 in conjunction with...

  9. 77 FR 42175 - Securities Act Industry Guides

    Science.gov (United States)

    2012-07-18

    ... Securities Act Industry Guides AGENCY: Securities and Exchange Commission. ACTION: Technical amendments... Disclosure by Bank Holding Companies (``Industry Guide 3''), and Guide 7, Description of Property by Issuers Engaged or to be Engaged in Significant Mining Operations (``Industry Guide 7''), of the Securities Act...

  10. 78 FR 17471 - Privacy Act of 1974

    Science.gov (United States)

    2013-03-21

    ... Privacy Act of 1974, OMB Guidelines on the Conduct of Matching Programs (54 FR 25818, June 19, 1989), OMB... and Disclosure, Internal Revenue Service, 1111 Constitution Avenue NW., Washington, DC 20224. Comments... Internal Revenue Service Privacy Act of 1974 AGENCY: Internal Revenue Service, Treasury. ACTION: IRS...

  11. 76 FR 70131 - Sunshine Act Notice

    Science.gov (United States)

    2011-11-10

    ... From the Federal Register Online via the Government Publishing Office EQUAL EMPLOYMENT OPPORTUNITY COMMISSSION Sunshine Act Notice AGENCY HOLDING THE MEETING: Equal Employment Opportunity Commission. DATE AND... Discrimination in Employment Act, and 3. Overcoming Barriers to the Employment of Veterans with...

  12. Pro farmer, pro industry land acquisition act

    OpenAIRE

    Varma, Vijaya Krushna Varma

    2015-01-01

    Varma suggests a new land acquisition act which is pro farmer, pro industry and pro development, and which leads to faster economic growth. My suggestions for new land acquisition act consist of 6 segments 1. Land acquisition 2. Categorisation of Land allotment 3. Time table for completion of projects 4. Compensation 5. Rehabilitation 6. Land management

  13. 76 FR 77558 - Sunshine Act Meeting; Notice

    Science.gov (United States)

    2011-12-13

    ... Counsel, at (202) 295-1500. Questions may be sent by electronic mail to FR_NOTICE_QUESTIONS@lsc.gov... or FR_NOTICE_QUESTIONS@lsc.gov , at least 2 business days in advance of the meeting. If a request is.... Consider and act on changes to LSC Bylaws necessitated by the DC Nonprofit Corporation Act of 2010....

  14. On Multiple Metonymies Within Indirect Speech Acts

    OpenAIRE

    Kosecki Krzysztof

    2007-01-01

    Indirect speech acts are frequently structured by more than a single metonymy. The metonymies are related not only to the illocutionary force of the utterances, but also function within the individual lexemes being their parts. An indirect speech act can thus involve not only multiple, but also multi-levelled operation of conceptual metonymy.

  15. 75 FR 76056 - Sunshine Act Notice

    Science.gov (United States)

    2010-12-07

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Sunshine Act Notice Cancellation of December 9, 2010 Board Meeting OPIC's Sunshine Act notice of its Board meeting was published in the Federal Register (Volume 75, Number 210, Page 67145)...

  16. 75 FR 55790 - Sunshine Act Meeting Notice

    Science.gov (United States)

    2010-09-14

    ... Energy Regulatory Commission Sunshine Act Meeting Notice September 9, 2010. The following notice of meeting is published pursuant to section 3(a) of the government in the Sunshine Act (Pub. L. No. 94-409..., LLC, and New York Canyon, LLC. EL10-36-000 Green Borders Geothermal, LLC v. Terra-Gen Dixie...

  17. Factors of Politeness and Indirect Speech Acts

    Institute of Scientific and Technical Information of China (English)

    杨雪梅

    2016-01-01

    Polite principle is influenced deeply by a nation's history,culture,custom and so on,therefor different countries have different understandings and expressions of politeness and indirect speech acts.This paper shows some main factors influencing a polite speech.Through this article,readers can comprehensively know about politeness and indirect speech acts.

  18. Acting green elicits a literal warm glow

    NARCIS (Netherlands)

    Taufik, Danny; Bolderdijk, Jan Willem; Steg, Linda

    2015-01-01

    Environmental policies are often based on the assumption that people only act environmentally friendly if some extrinsic reward is implicated, usually money(1,2). We argue that people might also be motivated by intrinsic rewards: doing the right thing (such as acting environmentally friendly) elicit

  19. Equationally Compact Acts : Coproducts / Peeter Normak

    Index Scriptorium Estoniae

    Normak, Peeter

    1998-01-01

    In this article equational compactness of acts and its generalizations are discussed. As equational compactness does not carry over to coproducts a slight generalization of c-equational campactness is introduced. It is proved that a coproduct of acts is c-equationally compact if and only if all components are c-equationally campact

  20. 76 FR 53702 - Sunshine Act Meeting

    Science.gov (United States)

    2011-08-29

    ...-backed issuers with a conditional exclusion from the definition of investment company. The second release... wide range of issues under the Investment Company Act raised by the use of derivatives by investment companies regulated under that Act. Item 2: The Commission will consider whether to issue two...

  1. Exploring primary care activities in ACT teams.

    Science.gov (United States)

    Vanderlip, Erik R; Williams, Nancy A; Fiedorowicz, Jess G; Katon, Wayne

    2014-05-01

    People with serious mental illness often receive inadequate primary and preventive care services. Federal healthcare reform endorses team-based care that provides high quality primary and preventive care to at risk populations. Assertive community treatment (ACT) teams offer a proven, standardized treatment approach effective in improving mental health outcomes for the seriously mentally ill. Much is known about the effectiveness of ACT teams in improving mental health outcomes, but the degree to which medical care needs are addressed is not established. The purpose of this study was to explore the extent to which ACT teams address the physical health of the population they serve. ACT team leaders were invited to complete an anonymous, web-based survey to explore attitudes and activities involving the primary care needs of their clients. Information was collected regarding the use of health screening tools, physical health assessments, provision of medical care and collaboration with primary care systems. Data was analyzed from 127 team leaders across the country, of which 55 completed the entire survey. Nearly every ACT team leader believed ACT teams have a role in identifying and managing the medical co-morbidities of their clientele. ACT teams report participation in many primary care activities. ACT teams are providing a substantial amount of primary and preventive services to their population. The survey suggests standardization of physical health identification, management or referral processes within ACT teams may result in improved quality of medical care. ACT teams are in a unique position to improve physical health care by virtue of having medically trained staff and frequent, close contact with their clients.

  2. Resource Conservation and Recovery Act Part B permit application

    International Nuclear Information System (INIS)

    The Waste Isolation Pilot Plant (WIPP) project was authorized by the Department of Energy National Security and Military Applications of Nuclear Energy Authorization Act of 1980 (Public Law 96-164) as a research and development facility to demonstrate the safe, environmentally sound disposal of transuranic (TRU) radioactive wastes derived from the defense activities of the United States. The WIPP facility is owned and operated by the US Department of Energy (DOE). The TRU waste to be received at WIPP consists largely of such items as laboratory glassware and utensils, tools, scrap metal, shielding, personnel protection equipment, and solidified sludges from the treatment of waste water. Approximately 60 percent of this waste is ''mixed,'' that is, it is also contaminated with hazardous waste or hazardous waste constituents as defined by the Resource Conservation and Recovery Act (RCRA) and by the New Mexico Hazardous Waste Management Regulations (HWMR-5). Therefore, emplacement of TRU mixed waste in the WIPP repository is subject to regulation under HWMR-5 and RCRA. The permit application under the Resource Conservation and Recovery Act for WIPP is divided into five volumes. This document, Volume 1, contains a site and facility description of WIPP; procedures for waste analysis and characterization, testing, monitoring, inspection, and training; hazard prevention, safety and security plans; plans for closure; and a discussion of other applicable laws. Also included are maps, photographs, and diagrams of the facilities and surrounding areas. 180 refs., 75 figs., 24 tabs

  3. Resource Conservation and Recovery Act, Part B Permit Application

    International Nuclear Information System (INIS)

    The Waste Isolation Pilot Plant (WIPP) project was authorized by the Department of Energy National Security and Military Applications of Nuclear Energy Authorization Act of 1980 (Public Law 96-164) as a research and development facility to demonstrate the safe, environmentally sound disposal of transuranic (TRU) radioactive wastes derived from the defense activities of the United States. The WIPP facility is owned and operated by the US Department of Energy (DOE). The TRU waste to be received at WIPP consists largely of such items as laboratory glassware and utensils, tools, scrap metal, shielding, personnel protection equipment, and solidified sludges from the treatment of waste water. Approximately 60 percent of this waste is ''mixed,'' that is, it is also contaminated with hazardous waste or hazardous waste constituents as defined by the Resource Conservation and Recovery Act (RCRA) and by the New Mexico Hazardous Waste Management Regulations (HWMR-5). Therefore, emplacement of TRU mixed waste in the WIPP repository is subject to regulation under HWMR-5 and RCRA. The permit application under the Resource Conservation and Recovery Act for WIPP is divided into five volumes. This document, Volume 4, contains Appendices C3, C4, and D1--D10. These appendices cover information on environmental impacts, site characterization, geology and hydrology of the area, monitoring of the environment, compatibility of waste forms and containers, and removal of volatile organic compounds (VOC)

  4. Nuclear Liability Act of 8 June 1972 as amended by the Act of 15 September 1989

    International Nuclear Information System (INIS)

    The 1972 Nuclear Liability Act has been amended by an Act 1989 to bring its provisions in line with those of the Paris Convention and the Brussels Supplementary Convention as amended respectively by the 1982 Protocols. The 1989 Act also raises the limit of the nuclear operator's liability from 42 million Finnish marks (approximately 8 million Special Draing Rights - SDRs) to 100 million SDRs

  5. 13 CFR 107.115 - 1940 Act and 1980 Act Companies.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false 1940 Act and 1980 Act Companies. 107.115 Section 107.115 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES Qualifying for an SBIC License Organizing An Sbic § 107.115 1940 Act and 1980...

  6. 45 CFR 2543.86 - Clean Air Act and the Federal Water Pollution Control Act.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Clean Air Act and the Federal Water Pollution..., HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Statutory Compliance § 2543.86 Clean Air Act and the Federal... regulations issued pursuant to the Clean Air Act (42 U.S.C. 7401 et seq.) and the Federal Water...

  7. Acting green elicits a literal warm glow

    Science.gov (United States)

    Taufik, Danny; Bolderdijk, Jan Willem; Steg, Linda

    2015-01-01

    Environmental policies are often based on the assumption that people only act environmentally friendly if some extrinsic reward is implicated, usually money. We argue that people might also be motivated by intrinsic rewards: doing the right thing (such as acting environmentally friendly) elicits psychological rewards in the form of positive feelings, a phenomenon known as warm glow. Given the fact that people's psychological state may affect their thermal state, we expected that this warm glow could express itself quite literally: people who act environmentally friendly may perceive the temperature to be higher. In two studies, we found that people who learned they acted environmentally friendly perceived a higher temperature than people who learned they acted environmentally unfriendly. The underlying psychological mechanism pertains to the self-concept: learning you acted environmentally friendly signals to yourself that you are a good person. Together, our studies show that acting environmentally friendly can be psychologically rewarding, suggesting that appealing to intrinsic rewards can be an alternative way to encourage pro-environmental actions.

  8. Reflection and Optimization of Primary English Teachers’Speech Acts Based on Speech Act Theory

    Institute of Scientific and Technical Information of China (English)

    HU Qi-hai

    2015-01-01

    The primary English teacher's speech acts have major impact on foreign language teaching and learning in primary school. Application of teacher,s speech acts in the classroom is actually a kind of selective process. From the perspective of Speech Act Theory, primary English teachers can optimize their speech acts with the strategies of activating the greetings with proper con⁃text information, standardizing teacher talk, choosing suitable questions,providing appropriate feedback for pupils ’classroom per⁃formances in order to improve the effectiveness of primary teachers,classroom speech acts.

  9. The Genetic Privacy Act and commentary

    Energy Technology Data Exchange (ETDEWEB)

    Annas, G.J.; Glantz, L.H.; Roche, P.A.

    1995-02-28

    The Genetic Privacy Act is a proposal for federal legislation. The Act is based on the premise that genetic information is different from other types of personal information in ways that require special protection. Therefore, to effectively protect genetic privacy unauthorized collection and analysis of individually identifiable DNA must be prohibited. As a result, the premise of the Act is that no stranger should have or control identifiable DNA samples or genetic information about an individual unless that individual specifically authorizes the collection of DNA samples for the purpose of genetic analysis, authorized the creation of that private information, and has access to and control over the dissemination of that information.

  10. French royal acts printed before 1601

    OpenAIRE

    Kim, Lauren J.

    2008-01-01

    This thesis is a study of royal acts printed in French before 1601. The kingdom of France is a natural place to begin a study of royal acts. It possessed one of the oldest judicial systems in Europe, which had been established during the reign of St Louis (1226-1270). By the sixteenth century, French kings were able to issue royal acts without any concern as to the distribution of their decrees. In addition, France was one of the leading printing centres in Europe. This research provides...

  11. Merchant shipping (Safety Convention) Act 1977

    International Nuclear Information System (INIS)

    When this Act comes into force, it will enable the United Kingdom to ratify and to give effect to the 1974 International Convention for the Safety of Life at Sea (the SOLAS Convention) which replaces the SOLAS Convention of 1960. Under the Act, the Secretary of State may make such rules as he considers appropriate regarding ships provided with nuclear power plants in accordance with Chapter VIII of the Annex to the 1974 Convention and to Recommendations attached to it, dealing with nuclear ships, and insofar as those provisions have not been implemented by the Merchant Shipping Acts 1894 to 1974. (NEA)

  12. A disjunctive conception of acting for reasons

    OpenAIRE

    Hornsby, Jennifer

    2008-01-01

    A disjunctivist conception of acting for reasons is introduced by way of showing that a view of acting for reasons must give a place to knowledge. Two principal claims are made. 1. This conception has a rôle analogous to that of the disjunctive conception that John McDowell recommends in thinking about perception; and when the two disjunctivist conceptions are treated as counterparts, they can be shown to have work to do in combination. 2. This conception of acting for reasons safeguards the ...

  13. Radioactive Material (Road Transport) Act 1991

    International Nuclear Information System (INIS)

    This Act came into force on 27 August 1991. It replaces earlier legislation dating from 1948 and enables the United Kingdom to give effect to the International Atomic Energy Agency's (IAEA) latest recommended Regulations for the Safe Transport of Radioactive Material. The new Act clarifies and extends the power of the Secretary of State to make regulations regarding, among other things, the design, labelling, handling, transport and delivery of packages containing radioactive material and the placarding of vehicles transporting such packages. The Act gives the Secretary of State the power to appoint inspectors to assist him in enforcing the regulations. (NEA)

  14. 75 FR 70778 - Privacy Act of 1974

    Science.gov (United States)

    2010-11-18

    ... information in this system is used to evaluate the qualifications of approximately 30,000 medical residents...) (Privacy Act) and guidelines issued by OMB (65 FR 77677), December 12, 2000. Approved: October 21,...

  15. Freedom of Information Act (FOIA) Plan

    Data.gov (United States)

    Office of Personnel Management — Executive Order (E.O.) 13,392 mandates that each federal agency shall have a Freedom of Information Act (FOIA) working plan with established goals and time frames...

  16. Human arm may act as antenna

    Science.gov (United States)

    Gaddie, J. C.; Wolfram, R. T.

    1978-01-01

    Wrist strap with copper strips is used as coupler of radio-frequency energy. Wires at midpoints of strips lead to radio-frequency device that acts as transmitter or receiver. Varying widths of copper strips produces somewhat different characteristics.

  17. 78 FR 26031 - Sunshine Act Notice

    Science.gov (United States)

    2013-05-03

    ... From the Federal Register Online via the Government Publishing Office EQUAL EMPLOYMENT OPPORTUNITY COMMISSION Sunshine Act Notice AGENCY HOLDING THE MEETING: Equal Employment Opportunity Commission DATE AND.... Wellness Programs Under Federal Equal Employment Opportunity Laws. Note: In accordance with the...

  18. RECOVERY ACT: TAPOCO PROJECT: CHEOAH UPGRADE

    Energy Technology Data Exchange (ETDEWEB)

    Tran, Paul

    2013-02-28

    Under Funding Opportunity Announcement Number: DE-FOA-0000120, Recovery Act: Hydroelectric Facility Modernization, Alcoa Power Generating Inc. (APGI), a fully owned subsidiary of Alcoa Inc., implemented major upgrades at its Cheoah hydroelectric facility near Robbinsville, North Carolina.

  19. 78 FR 52496 - Sunshine Act Meetings

    Science.gov (United States)

    2013-08-23

    ...: Discuss and select an organization structure for the Foundation staff and provide the Acting Executive... agency #0;statements of organization and functions are examples of documents #0;appearing in this...

  20. 76 FR 34230 - Sunshine Act Meeting

    Science.gov (United States)

    2011-06-13

    ... Protection Act of 2010. Discussion Agenda: Memorandum and resolution re: Final Rule on Risk-Based Capital Standards: Advanced Capital Adequacy Framework--Basel II; Establishment of a Risk-Based Capital Floor....

  1. Magnuson-Stevens Fishery Conservation Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Magnuson-Stevens Fishery Conservation and Management Act (MSA) is the primary law governing marine fisheries management in U.S. federal waters. It has since...

  2. Freedom of Information Act (FOIA) Tracking System

    Data.gov (United States)

    Office of Personnel Management — Tracking system which allows for the input of the Freedom of Information Act (FOIA) request date, compiles the due date, information pertaining to the request, name...

  3. Marine Debris Research, Prevention, and Reduction Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Marine Debris Research, Prevention, and Reduction Act legally establishes the National Oceanic and Atmospheric Administration's (NOAA) Marine Debris Program....

  4. Comprehensive Environmental Response, Compensation and Liability Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), commonly known as Superfund, provides a federal "superfund" to clean up...

  5. 2010 E-Government Act Report

    Data.gov (United States)

    Department of Veterans Affairs — This report describes VA’s accomplishments in implementing the requirements of the E-Government Act of 2002, Section 202(g) and the Open Government Directive dated...

  6. Annual Freedom of Information Act (FOIA) Reports

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA makes annual reports of progress made on Freedom of Information Act (FOIA) requests. This database contains PDF and XML versions of reports from 1999 to the...

  7. Recovery Act. Tapoco project. Cheoah upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Tran, Paul [Alcoa Inc., Alcoa Center, PA (United States)

    2013-10-02

    Under Funding Opportunity Announcement Number: DE-FOA-0000120, Recovery Act: Hydroelectric Facility Modernization, Alcoa Power Generating Inc. (APGI), a fully owned subsidiary of Alcoa Inc., implemented major upgrades at its Cheoah hydroelectric facility near Robbinsville, North Carolina.

  8. Atomic Energy Act 1953-1966

    International Nuclear Information System (INIS)

    The Atomic Energy Act 1953-1966 establishes the Australian Atomic Energy Commission and lays down its powers, duties, rules of procedure and financing. The members of the Commission are appointed by the Governor-General. It is responsible, inter alia, for all activities covering uranium research, mining and trading as well as for atomic energy development and nuclear plant construction and operation. Its duties also include training of scientific research workers and collection and dissemination of information on atomic energy. For purposes of security, the Act further-more prescribes sanctions in relation to unauthorised acquisition or communication of information on this subject. Finally, the Act repeals the Atomic Energy (Control of Materials) Act 1946 and 1952. (NEA)

  9. 31 CFR 0.216 - Privacy Act.

    Science.gov (United States)

    2010-07-01

    ... 1974, as amended (5 U.S.C. 552a), shall comply with the conduct regulations delineated in 31 CFR 1.28(b). ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Privacy Act. 0.216 Section 0.216... RULES OF CONDUCT Rules of Conduct § 0.216 Privacy Act. Employees involved in the design,...

  10. Missed Opportunities: The Vaccine Act of 1813

    OpenAIRE

    Singla, Rohit K.

    1998-01-01

    This Paper simply exposes discontinuities between the theories and the history of the Vaccine Act, suggesting lines of further study. The focus throughout this Paper is on "getting the facts right," i.e., thoroughly recounting the history of the Vaccine Act. Part II of the paper provides some necessary historical background regarding the horrors of smallpox, the breakthrough of vaccination, and the difficulties encountered in implementing vaccination in early 19th century America. In particul...

  11. 43 CFR 2.47 - Records subject to Privacy Act.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Records subject to Privacy Act. 2.47 Section 2.47 Public Lands: Interior Office of the Secretary of the Interior RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT Privacy Act § 2.47 Records subject to Privacy Act. The Privacy Act applies to...

  12. 78 FR 17176 - Federal Acquisition Regulation; Defense Base Act

    Science.gov (United States)

    2013-03-20

    ... Act as extended by the Defense Base Act. II. Discussion and Analysis The Defense Base Act of 1941...-insurer; to submit a timely, written report to the Department of Labor (DOL) in the event of an employee's... (Defense Base Act), merely clarify the existing requirements set forth in the Defense Base Act of 1941...

  13. The Nuclear Waste Policy Act, as amended, with appropriations acts appended. Revision 1

    International Nuclear Information System (INIS)

    This act provides for the development of repositories for the disposal of high-level radioactive wastes, low-level radioactive wastes, and spent nuclear fuels. In addition, it establishes research and development programs, as well as demonstration programs regarding the disposal of these wastes. This Act consists of the Act of Jan. 7, 1983 (Public Law 97-425; 96 Stat. 2201), as amended by Public Law 100-203 and Public Law 102-486

  14. The Nuclear Waste Policy Act, as amended, with appropriations acts appended. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-02-01

    This act provides for the development of repositories for the disposal of high-level radioactive wastes, low-level radioactive wastes, and spent nuclear fuels. In addition, it establishes research and development programs, as well as demonstration programs regarding the disposal of these wastes. This Act consists of the Act of Jan. 7, 1983 (Public Law 97-425; 96 Stat. 2201), as amended by Public Law 100-203 and Public Law 102-486.

  15. Entropic characterization of quantum operations

    CERN Document Server

    Roga, Wojciech; Zyczkowski, Karol

    2011-01-01

    We investigate decoherence induced by a quantum channel in terms of minimal output entropy and of map entropy. The latter is the von Neumann entropy of the Jamiolkowski state of the channel. Both quantities admit q-Renyi versions. We prove additivity of the map entropy for all q. For the case q = 2, we show that the depolarizing channel has the smallest map entropy among all channels with a given minimal output Renyi entropy of order two. This allows us to characterize pairs of channels such that the output entropy of their tensor product acting on a maximally entangled input state is larger than the sum of the minimal output entropies of the individual channels. We conjecture that for any channel {\\Phi}1 acting on a finite dimensional system there exists a class of channels {\\Phi}2 sufficiently close to a unitary map such that additivity of minimal output entropy for {\\Psi}1 x {\\Psi}2 holds.

  16. Characterization of radioactive hazardous waste

    International Nuclear Information System (INIS)

    The characterization of radioactive hazardous waste, also known as transuranic 'mixed waste' has to be completed before it can be classified for proper treatment (incinerator, mechanical compaction or thermal treatment), packing, and transport. The characterization of the TRU mixed waste is not only complex process but rather an expensive undertaking. The process knowledge is the basic foundation of characterization. It is the documented knowledge of processes and materials that generated the waste. The transuranic waste Quality Assurance Program Plan (QAPP) defines the Data Quality Objectives (DQO's) and provides the scope of analytical parameters and methods required to accurately characterize the radioactive mixed waste. Based on the historical data and process knowledge a sampling and analysis plan can be developed to characterize the radioactive hazardous waste. Based on the characterization, an assessment of the regulatory status can be made before the waste could be accepted for disposal at the WIPP facility. The Waste Acceptance Criteria (WAC) developed by WIPP defines the parameters for receiving and final disposal of the TRU waste. The sets of criteria, such as: heat generated, fissile gram equivalent (FGE), plutonium-equivalent (PE) curies, and specifications of a dose rate have to be met before the waste is accepted for deep geological disposal. The characterization of radioactive waste becomes even more complex due to the presence of iron base metals/alloys, aluminum base metals/alloys, organic, chelating agents that are mixed with plastic, rubber, cellulose, soils and cement. Some of the modern characterization technologies that are under development and currently used for TRU mixed wastes are: nondestructive examination, nondestructive assay, headspace gas analysis, and drum coring for Resources Conservation Recovery Act (RCRA) sampling. (author)

  17. Administrative Changes (Consequentia Provisions) Act 1978, No. 36 of 1978

    International Nuclear Information System (INIS)

    This Act which amends a series of Acts from the administrative viewpoint also amends the 1953 Atomic Energy Act by laying down that, wherever mentioned, the Treasurer must be substituted by the Minister of Finance. (NEA)

  18. Interpreting the Computer Fraud and Abuse Act

    Directory of Open Access Journals (Sweden)

    Lee Goldman

    2012-12-01

    Full Text Available Computers play an integral role in today’s society.  While computers provide many benefits, they are increasingly used as tools for wrongdoing, causing estimated losses of billions of dollars each year. Computer hackers can, among other things, fraudulently alter accounts, steal business or personal information, and corrupt or disable computer systems.  Congress enacted and has repeatedly amended the Computer Fraud and Abuse Act (“CFAA” to combat the increasing proliferation of computer crimes. This article argues that the Courts of Appeals have not adequately interpreted the foundational terms of the Act and recommends an interpretation of the Act that builds upon the narrower definitions to comprehensively define the scope of the Act’s coverage.

  19. US Energy Policy Act of 2005

    OpenAIRE

    Neff, Shirley; Myers Jaffe, Amy

    2005-01-01

    In the aftermath of the destruction wrought on the US energy patch, especially oil and gas production and refining, by Hurricanes Katrina and Rita, the failure of the long awaited Energy Policy Act of 2005 (EPACT 2005 or Act) to address the country’s energy challenges is all too apparent. Even before the storm, the energy bill was characterised more as a grab bag for special interests than as the kind of ‘comprehensive’ energy strategy needed to address long-term core American economic, envir...

  20. Convention on nuclear safety. Final act

    International Nuclear Information System (INIS)

    The Diplomatic Conference, which was convened by the International Atomic Energy Agency at its Headquarters from 14 to 17 June 1994, adopted the Convention on Nuclear Safety reproduced in document INFCIRC/449 and the Final Act of the Conference. The text of the Final Act of the Conference, including an annexed document entitled ''Some clarification with respect to procedural and financial arrangements, national reports, and the conduct of review meetings, envisaged in the Convention on Nuclear Safety'', is reproduced in the Attachment hereto for the information of all Member States

  1. Long-acting preparations of exenatide

    Science.gov (United States)

    Cai, Yunpeng; Wei, Liangming; Ma, Liuqing; Huang, Xiwen; Tao, Anqi; Liu, Zhenguo; Yuan, Weien

    2013-01-01

    Exenatide has been widely used for the treatment of type 2 diabetes mellitus. However, its short plasma half-life of 2.4 hours has limited its clinical application. The exenatide products on the market, twice-daily Byetta™ and once-weekly Bydureon™ (both Amylin Pharmaceuticals, San Diego, CA, USA), are still not perfect. Many researchers have attempted to prolong the acting time of exenatide by preparing sustained-release dosage forms, modifying its structure, gene therapies, and other means. This review summarizes recent advances in long-acting exenatide preparations. PMID:24039406

  2. Self-acting geometry for noncontact seals

    Science.gov (United States)

    Allen, G. P.

    1981-01-01

    Performance ot two self acting seal designs for a liquid oxygen (LOX) turbopump was predicted over ranges of pressure differential and speed. Predictions were compared with test results. Performance of a radial face seal for LOX was predicted up to 448 N/cu cm and 147 m/sec. Performance of a segmented circumferential seal for helium was predicted up to 69 N/cu cm and 189 m/sec. Results confirmed predictions of noncontact operation. Qualitative agreement between test and analysis was found. The LOX face seal evidently operated with mostly liquid in the self acting geometry and mostly gas across the dam.

  3. Speech Act Theory. A Critical Overview

    OpenAIRE

    Loftur Árni Björgvinsson 1983

    2011-01-01

    This essay examines J.L. Austin's theory regarding speech acts, or how we do things with words. It starts by reviewing the birth and foundation of speech act theory as it appeared in the 1955 William James Lectures at Harvard before going into what Austin's theory is and how it can be applied to the real world. The theory is explained and analysed both in regards to its faults and advantages. Proposals for the improvement of the theory are then developed, using the ideas of other scholars ...

  4. Comparing Clean Water Act Section 316(b Policy Options

    Directory of Open Access Journals (Sweden)

    John Kadvany

    2002-01-01

    Full Text Available This paper develops a comparative framework for policy proposals involving fish protection and Section 316(b of the Clean Water Act (CWA. Section 316(b addresses the impingement and entrainment of fish by cooling-water intake structures used principally by steam electric power plants. The framework is motivated by examining the role of adverse environmental impacts (AEIs in the context of Section 316(b decision making. AEI is mentioned in Section 316(b, but not defined. While various AEI options have been proposed over the years, none has been formalized through environmental regulations nor universally accepted. Using a multiple values approach from decision analysis, AEIs are characterized as measurement criteria for ecological impacts. Criteria for evaluating AEI options are identified, including modeling and assessment issues, the characterization of ecological value, regulatory implementation, and the treatment of uncertainty. Motivated by the difficulties in defining AEI once and for all, a framework is introduced to compare options for 316(b decision making. Three simplified policy options are considered, each with a different implicit or explicit AEI approach: (1 a technology-driven rule based on a strict reading of the 316(b regulatory text, and for which any impingement and entrainment count as AEI, (2 a complementary, open-ended risk-assessment process for estimating population effects with AEI characterized on a site-specific basis, and (3 an intermediate position based on proxy measures such as specially constructed definitions of littoral zone, sensitive habitat, or water body type. The first two proposals correspond roughly to responses provided, respectively, by the Riverkeeper environmental organization and the Utility Water Act Group to the U.S. Environmental Protection Agency (EPA’s proposed 316(b new facilities rule of August 2000; the third example is a simplified form of the EPA’s proposed August 2000 new facilities

  5. 76 FR 40860 - Notice of Intent To Prepare an Environmental Assessment for Pedestrian Safety Enhancement Act of...

    Science.gov (United States)

    2011-07-12

    ... NEPA. This notice also provides guidance for participating in the scoping process and additional...\\ 73 FR 31187; May 30, 2008. \\4\\ The presentations are in document 0012 and the transcript is in... these vehicles. The Japanese Ministry of Land, Infrastructure, Transport and Tourism (MLIT),...

  6. Act No. 11/87 of 7 april - Basic environment act

    International Nuclear Information System (INIS)

    The purpose of this Act is to provide the basis for an environmental policy in Portugal. Section 25 of the Act deals with radioactive substances. It provides that any contamination likely to be caused by these substances should be controlled with a view to preventing its effects on the health and welfare of the population and specifies the methods for such control

  7. 76 FR 64115 - Privacy Act of 1974; Privacy Act System of Records

    Science.gov (United States)

    2011-10-17

    ... (September 30, 2009, 74 FR 50247) as the records maintained are all published publicly. DATES: This change... notice, Biographical Records for Public Affairs (September 30, 2009, 74 FR 50247). All information... SPACE ADMINISTRATION Privacy Act of 1974; Privacy Act System of Records AGENCY: National Aeronautics...

  8. 78 FR 25685 - Magnuson-Stevens Act Provisions; Implementation of the Shark Conservation Act of 2010

    Science.gov (United States)

    2013-05-02

    ... final rule to implement the SFPA on February 11, 2002 (67 FR 6194). ] In 2010, the President signed into... the Moratorium Protection Act regulations consistent with the SCA on January 16, 2013 (78 FR 3338... Provisions; Implementation of the Shark Conservation Act of 2010 AGENCY: National Marine Fisheries...

  9. 78 FR 29659 - Forfeiture Procedures Under the Endangered Species Act and the Lacey Act Amendments

    Science.gov (United States)

    2013-05-21

    ....S.C. 1531 et seq.), was passed to prevent the extinction of native and non- native animals and... Animal and Plant Health Inspection Service 7 CFR Part 356 RIN 0579-AD50 Forfeiture Procedures Under the Endangered Species Act and the Lacey Act Amendments AGENCY: Animal and Plant Health Inspection Service,...

  10. 75 FR 67145 - Sunshine Act: Public Hearing

    Science.gov (United States)

    2010-11-01

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Sunshine Act: Public Hearing TIME AND DATE: 2 p.m., Wednesday, November 24, 2010. PLACE: Offices...: Hearing open to the Public at 2 p.m. PURPOSE: Public Hearing in conjunction with each meeting of...

  11. 77 FR 10784 - Sunshine Act Meeting

    Science.gov (United States)

    2012-02-23

    ... CORPORATION Finance, Budget & Program Committee of the Board of Directors; Sunshine Act Meeting DATES: Time..., Washington, DC 20005. Status: Open. CONTACT PERSON FOR MORE INFORMATION: Erica Hall, Assistant Corporate... Report IV. NFMC Interest Income Budget V. Lease Update VI. Corporate Scorecard & Dashboard VII....

  12. 75 FR 39205 - Sunshine Act Notice

    Science.gov (United States)

    2010-07-08

    ... From the Federal Register Online via the Government Publishing Office COMMISSION ON CIVIL RIGHTS Sunshine Act Notice AGENCY: United States Commission on Civil Rights. ACTION: Notice of meeting. DATE AND.... Program Planning Approval of Recommendations for Briefing Report on Encouraging Minority Students...

  13. The Dutch archival act and harmonisation

    NARCIS (Netherlands)

    Havermans, J.B.G.A.

    2010-01-01

    ln 1993, the first document on indoor air quality parameters was presented to improve the storage conditions for archival records. Since 1995, these recommendations were included in the Dutch Archival Act. The conditions were based on international and national studies, presented by Vosteen for the

  14. The Employee Polygraph Protection Act of 1988.

    Science.gov (United States)

    Duffy, Patrick J.

    1989-01-01

    Aspects of the new Employee Polygraph Protection Act are discussed, including exemptions, prohibited devices, limitations, exceptions, injury and access requirements, reasonable suspicion, drug industry investigations, procedural requirements, disclosure, basis for discharge, enforcement and remedies, and preemption and existing state laws. (MSE)

  15. 76 FR 62297 - Privacy Act: Implementation

    Science.gov (United States)

    2011-10-07

    ... the Treasury. Effective January 24, 2003, the Homeland Security Act of 2002 divided that Bureau into... cigarette papers and tubes) of title 26 U.S.C., the Internal Revenue Code of 1986, as amended (IRC). TTB... IRC and title 27 of the U.S.C. (relating to alcohol). As a result of the organizational...

  16. Are Acts of Supererogation Always Praiseworthy?

    NARCIS (Netherlands)

    Archer, Alfred

    2016-01-01

    It is commonly assumed that praiseworthiness should form part of the analysis of supererogation. I will argue that this view should be rejected. I will start by arguing that, at least on some views of the connection between moral value and praiseworthiness, it does not follow from the fact that acts

  17. The Genetic Privacy Act and commentary

    Energy Technology Data Exchange (ETDEWEB)

    Annas, G.J.; Glantz, L.H.; Roche, P.A.

    1995-02-28

    The Genetic Privacy Act is a proposal for federal legislation. The Act is based on the premise that genetic information is different from other types of personal information in ways that require special protection. The DNA molecule holds an extensive amount of currently indecipherable information. The major goal of the Human Genome Project is to decipher this code so that the information it contains is accessible. The privacy question is, accessible to whom? The highly personal nature of the information contained in DNA can be illustrated by thinking of DNA as containing an individual`s {open_quotes}future diary.{close_quotes} A diary is perhaps the most personal and private document a person can create. It contains a person`s innermost thoughts and perceptions, and is usually hidden and locked to assure its secrecy. Diaries describe the past. The information in one`s genetic code can be thought of as a coded probabilistic future diary because it describes an important part of a unique and personal future. This document presents an introduction to the proposal for federal legislation `the Genetic Privacy Act`; a copy of the proposed act; and comment.

  18. 78 FR 33862 - Sunshine Act Meeting; Notice

    Science.gov (United States)

    2013-06-05

    ... Counsel, at (202) 295-1500. Questions may be sent by electronic mail to FR_NOTICE_QUESTIONS@lsc.gov . ACCESSIBILITY: LSC complies with the Americans with Disabilities Act and Section 504 of the 1973 Rehabilitation...- 1500 or FR_NOTICE_QUESTIONS@lsc.gov , at least 2 business days in advance of the meeting. If a...

  19. 76 FR 78701 - Sunshine Act Meeting Notice

    Science.gov (United States)

    2011-12-19

    ... mail to FR_NOTICE_QUESTIONS@lsc.gov . ACCESSIBILITY: LSC complies with the Americans with Disabilities... telephonically should contact Katherine Ward, at (202) 295-1500 or FR_NOTICE_QUESTIONS@lsc.gov , at least 2... recommendations of the Board's Operations & Regulations Committee on changes to LSC Bylaws. 3. Consider and act...

  20. ACT Plan: Technical Manual. 2013/2014

    Science.gov (United States)

    ACT, Inc., 2013

    2013-01-01

    This manual contains information about the American College Test (ACT) Plan® program. The principal focus of this manual is to document the Plan program's technical adequacy in light of its intended purposes. This manual supersedes the 2011 edition. The content of this manual responds to requirements of the testing industry as established in the…

  1. Indian Child Welfare Act Proceedings. Final rule.

    Science.gov (United States)

    2016-06-14

    This final rule adds a new subpart to the Department of the Interior's (Department) regulations implementing the Indian Child Welfare Act (ICWA), to improve ICWA implementation. The final rule addresses requirements for State courts in ensuring implementation of ICWA in Indian child-welfare proceedings and requirements for States to maintain records under ICWA.

  2. 76 FR 71293 - Privacy Act; Implementation

    Science.gov (United States)

    2011-11-17

    ...)(3). These provisions of the Privacy Act provide for the release of the disclosure accounting... disclosure accounting would put the subject of an investigation on notice that an investigation exists and... an investigation with an accurate accounting of the date, nature, and purpose of each disclosure...

  3. 78 FR 66893 - Sunshine Act Notice

    Science.gov (United States)

    2013-11-07

    ... Sunshine Act Notice AGENCY: United States Commission on Civil Rights. ACTION: Notice of Business Meeting..., Washington, DC 20425. Meeting Agenda I. Approval of Agenda II. Office of General Counsel Ethics Training: Expiration of Appointments and Applicable Ethics Rules III. Program Planning Review and Vote on the...

  4. 78 FR 69551 - Privacy Act; Implementation

    Science.gov (United States)

    2013-11-20

    ... of the Secretary 32 CFR Part 319 Privacy Act; Implementation AGENCY: Defense Intelligence Agency, DoD. ACTION: Direct final rule with request for comments. SUMMARY: Defense Intelligence Agency (DIA) is..., Safety, Health, and Environmental Management Records. This direct final rule makes...

  5. J. B. Adams Acting Director-General

    CERN Multimedia

    1960-01-01

    After the tragic death of Prof. C. J. Bakker, the Council of CERN held an emergency meeting on May 3, 1960. Following this session, Mr. F. de Rose, President of the Council of the European Organization for Nuclear Research, announced the appointment of Mr. J. B. Adams, Director of the PS division to the post of acting Director-General.

  6. An Unselfish Act: Graffiti in Art Education

    Science.gov (United States)

    Eldridge, Laurie A.

    2013-01-01

    Graffiti artist Sentrock sees his graffiti as a selfless act, a way of giving back to the community--when done legally--and inspires a group of middle school students. This is a case study of an artist and educator who teaches about graffiti art in public schools. He is unique in that he delineates between graffiti art and vandalism, and teaches…

  7. Barnsley Responds to the 1981 Act.

    Science.gov (United States)

    Conway, Jim; Hepworth, Roy

    1987-01-01

    A case study of a local education agency (LEA) in Barnsley, England reveals how one LEA implemented the 1981 Education Act. A description of LEA characteristics is followed by a discussion of assessment procedures (e.g., annual screening and a Teacher Information Package) and a within-child interpretation of special needs. (JW)

  8. A karyopherin acts in localized protein synthesis

    NARCIS (Netherlands)

    Veenhoff, Liesbeth M.; Meinema, Anne C.; Poolman, Bert

    2010-01-01

    Multiple mechanisms are in place to regulate adequate synthesis of proteins, ranging from ways to ensure sequence fidelity, polypeptide folding and protein modification, to control of amounts and subcellular localization of the molecules. Some of these mechanisms act at the level of mRNA export and

  9. Lowy Named Acting NCI Director April 2015

    Science.gov (United States)

    Douglas Lowy, M.D., today was officially named the National Cancer Institute’s Acting Director. Dr. Lowy, a cancer researcher for more than 40 years, received the National Medal of Technology and Innovation from President Obama in 2014 for his research th

  10. 76 FR 27369 - Sunshine Act Meetings

    Science.gov (United States)

    2011-05-11

    ... soon as possible to allow time to make arrangements. Dated: May 9, 2011. Aaron Bishop, Executive... DISABILITY Sunshine Act Meetings TIME AND DATES: The board meeting will be held on Thursday, May 19, 2011, 1... (202) 272-2022; or may also be e-mailed to ncd@ncd.gov at any time. PORTIONS OPEN TO THE PUBLIC:...

  11. 78 FR 70944 - Sunshine Act Meeting Notice

    Science.gov (United States)

    2013-11-27

    ... Commission will consider and act upon the following in open session: United Mine Workers of America on behalf... America on behalf of Hoy v. Emerald Coal Resources, LP, Docket No. PENN 2012-251-D (Issues include whether... attending this meeting who requires special accessibility features and/or auxiliary aids, such as...

  12. Manslaughter Act may catch out the unwary.

    Science.gov (United States)

    Rogers, Gary

    2009-02-01

    The key areas that NHS Trusts and other organisations running healthcare facilities need to consider, and the risk audit processes recommended, to minimise their risk of prosecution under the Corporate Manslaughter & Homicide Act should fatalities occur on their premises, were examined by Gary Rogers, a chartered surveyor at Faithful + Gould, at the Healthcare Facilities Consortium's recent 2008 Annual Conference. PMID:19297842

  13. 76 FR 72000 - Patent, Trademark & Copyright Acts

    Science.gov (United States)

    2011-11-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Geological Survey Patent, Trademark & Copyright Acts AGENCY: U.S. Geological Survey, Interior. ACTION: Notice of Prospective Intent to Award Exclusive License. SUMMARY: The United States Geological Survey...

  14. Human Rights Act, 12 February 1987.

    Science.gov (United States)

    1987-01-01

    This document reprints major provisions of the Yukon's (Canada) 1987 Human Rights Act. The Act furthers the public policy that every individual is free and equal in dignity and rights, seeks to discourage and eliminate discrimination, and promotes the underlying principles of Canadian and international human rights instruments. Part 1 contains a Bill of Rights that protects the right to freedom of: 1) religion and conscience, 2) expression, 3) assembly and association, and 4) to enjoyment and disposition of property. Part 2 prohibits discrimination based on ancestry (including color and race), national origin, ethnic or linguistic background or origin, age, sex (including pregnancy), and marital or family status. Discrimination is also prohibited when offering services, goods, or facilities to the public; in connection with employment; in connection with membership in trade unions or trade, occupational, or professional associations; and in negotiation or performance of public contracts. The Bill of Rights lists reasonable causes for discrimination as well as exemptions, including preferential treatment for organization or family members or employment in a private home. Special programs and affirmative action programs are specifically not considered discrimination under this Act. The Act sets forth rules for providing equal pay for work of equal value and creates a Yukon Human Rights Commission to promote human rights and assist adjudication of complaints. PMID:12346749

  15. 77 FR 12553 - Sunshine Act Meetings

    Science.gov (United States)

    2012-03-01

    ... From the Federal Register Online via the Government Publishing Office COMMISSION ON CIVIL RIGHTS Sunshine Act Meetings AGENCY: United States Commission on Civil Rights. ACTION: Notice of meeting. DATE AND... Report Update Human Trafficking Briefing Update Immigration Briefing Update. Discussion of...

  16. 78 FR 42551 - Sunshine Act Meeting Notice

    Science.gov (United States)

    2013-07-16

    .... LOCATION: Millennium Ballroom, Warwick Hotel, 1776 Grant Street, Denver, Colorado 80203. PUBLIC OBSERVATION... 3. Consider and act on a Revised Consolidated Operating Budget for FY 2013, including internal... (202) 295-1628. Questions may be sent by electronic mail to FR_NOTICE_QUESTIONS@lsc.gov ....

  17. 77 FR 59014 - Sunshine Act Meeting; Notice

    Science.gov (United States)

    2012-09-25

    ... resume at 8:00 a.m., EDT. LOCATION: Hilton Durham Hotel, 3800 Hillsborough Road, Durham, North Carolina... Carol Bergman 7. Consider and act on Resolution #2012-0XX, Temporary Operating Budget for FY 2013... & General Counsel, at (202) 295-1500. Questions may be sent by electronic mail to...

  18. 77 FR 60376 - Sunshine Act Notice

    Science.gov (United States)

    2012-10-03

    ... Sunshine Act Notice AGENCY: United States Commission on Civil Rights. ACTION: Notice of business meeting... Planning Update and Discussion of Projects Update on The Civil Rights Implications of Eminent Domain Abuse... Chief of Regional Programs' report OGC Training: Ethics Rules Relating to Teaching, Speaking,...

  19. 78 FR 11632 - Sunshine Act Meeting Notice

    Science.gov (United States)

    2013-02-19

    ... SAFETY BOARD Sunshine Act Meeting Notice Federal Register CITATION OF PREVIOUS ANNOUCEMENT: 78 FR 4393... January 22, 2013, (78 FR 4393), concerning a two-session public meeting and hearing on March 14, 2013, at... 6:30 p.m. instead of 7:00 p.m.; (3) the topic of safety culture at the Pantex Plant in Session...

  20. 78 FR 40690 - Sunshine Act Meetings

    Science.gov (United States)

    2013-07-08

    ... From the Federal Register Online via the Government Publishing Office COMMISSION ON CIVIL RIGHTS Sunshine Act Meetings AGENCY: United States Commission on Civil Rights ACTION: Revised Notice of Business... Report Status Update on the Federal Civil Rights Engagement with Arab and Muslim American...

  1. 77 FR 65856 - Sunshine Act Meeting

    Science.gov (United States)

    2012-10-31

    ... Sunshine Act Meeting AGENCY: United States Commission on Civil Rights. ACTION: Notice of briefing and... public. Topic: The Federal Civil Rights Engagement With Arab and Muslim American Communities Post 9/11. I. Introductory Remarks by Chairman II. Panel I: Arab & Muslim American Civil Rights Organizations...

  2. 78 FR 40426 - Sunshine Act Notice

    Science.gov (United States)

    2013-07-05

    ... From the Federal Register Online via the Government Publishing Office COMMISSION ON CIVIL RIGHTS Sunshine Act Notice AGENCY: United States Commission on Civil Rights. ACTION: Notice of Business Meeting... Report Status Update on the Federal Civil Rights Engagement with Arab and Muslim American...

  3. 78 FR 6289 - Sunshine Act Notice

    Science.gov (United States)

    2013-01-30

    ... From the Federal Register Online via the Government Publishing Office COMMISSION ON CIVIL RIGHTS Sunshine Act Notice AGENCY: United States Commission on Civil Rights. ACTION: Notice of briefing and... Arab & Muslim Communities Post 9/11 briefing Update on the Assessing the Impact of Criminal...

  4. 78 FR 21343 - Sunshine Act Meeting

    Science.gov (United States)

    2013-04-10

    ... From the Federal Register Online via the Government Publishing Office COMMISSION ON CIVIL RIGHTS Sunshine Act Meeting AGENCY: United States Commission on Civil Rights. ACTION: Notice of Briefing and... & Muslim Communities Post 9/11 briefing Update on the Assessing the Impact of Criminal Background...

  5. 76 FR 75881 - Sunshine Act Meeting

    Science.gov (United States)

    2011-12-05

    ... Sunshine Act Meeting AGENCY HOLDING THE MEETING: Federal Maritime Commission. TIME AND DATE: December 8... Proposal of the Ministry of Transport of the People's Republic of China for Adjustment of the Amount for... the Liner Shipping Conference Exemption from Competition Laws-Discussion of Bureau of Trade...

  6. 76 FR 51869 - Privacy Act Implementation

    Science.gov (United States)

    2011-08-19

    ... agency or entity (i.e. passport, passport card, driver's license, ID card, etc.), or one form of... (i.e. passport, passport card, driver's license, ID card, etc.) and a properly authenticated birth... regulation on the Privacy Act at 12 CFR part 1204 (74 FR 33907 (July 14, 2009)). The final...

  7. 75 FR 39576 - Sunshine Act; Board Meeting

    Science.gov (United States)

    2010-07-09

    ... From the Federal Register Online via the Government Publishing Office INTER-AMERICAN FOUNDATION Sunshine Act; Board Meeting Time and Date: July 12, 2010; 2 p.m.-3:30 p.m. ] Place: 901 N. Stuart Street, Tenth Floor, Arlington, Virginia 22203. Status: Closed session as provided in 22 CFR 1004.4(f)....

  8. 77 FR 71611 - Sunshine Act; Board Meeting

    Science.gov (United States)

    2012-12-03

    ... Sunshine Act; Board Meeting TIME AND DATE: December 10, 2012. 9:00 a.m.-12:45 p.m. PLACE: Woodrow Wilson... September 24, 2012, Meeting of the Board of Directors Presentation of Resolution Honoring Service of Kay Arnold Carrying Out the IAF's Strategic Plan Management Report Setting Next Board Meetings PORTIONS TO...

  9. 76 FR 28756 - Sunshine Act Meeting Notice

    Science.gov (United States)

    2011-05-18

    ... COMMUNITY SERVICE Sunshine Act Meeting Notice The White House Council for Community Solutions gives notice... National and Community Service, 10th Floor, Room 10911, 1201 New York Avenue, NW., Washington, DC 20525... TO BE CONSIDERED: The purpose of this meeting is to review what the Council has learned through...

  10. 77 FR 2962 - Sunshine Act Meeting Notice

    Science.gov (United States)

    2012-01-20

    ... COMMUNITY SERVICE Sunshine Act Meeting Notice The White House Council for Community Solutions gives notice... 100-day initiative to unite all citizens to go ``All In'' for youth. The purpose of this meeting is to... Service, 10th Floor, Room 10911, 1201 New York Avenue NW., Washington, DC 20525. Phone: (202)...

  11. 76 FR 38371 - Sunshine Act Meeting

    Science.gov (United States)

    2011-06-30

    ... COMMUNITY SERVICE Sunshine Act Meeting The White House Council for Community Solutions gives notice of the... for National and Community Service, 10th Floor, Room 10911, 1201 New York Avenue, NW., Washington, DC... site: http://www.serve.gov/communitysolutions . STATUS: Open. MATTERS TO BE CONSIDERED: The purpose...

  12. 77 FR 23466 - Sunshine Act Meeting

    Science.gov (United States)

    2012-04-19

    ... COMMUNITY SERVICE Sunshine Act Meeting The White House Council for Community Solutions gives notice of the... House Council for Community Solutions, Corporation for National and Community Service, 10th Floor, Room...://www.serve.gov/communitysolutions . STATUS: Open. MATTERS TO BE CONSIDERED: The purpose of this...

  13. 76 FR 1604 - Sunshine Act Meeting Notice

    Science.gov (United States)

    2011-01-11

    ... COMMUNITY SERVICE Sunshine Act Meeting Notice The White House Council for Community Solutions gives notice... National and Community Service, 10th Floor, Room 10911, 1201 New York Avenue, NW., Washington, DC 20525... TO BE CONSIDERED: The purpose of this meeting is to review the Council's charge, discuss the...

  14. 78 FR 46555 - Privacy Act Regulations

    Science.gov (United States)

    2013-08-01

    ... civil activity will be collected in support of law enforcement, homeland security, and security... Case Investigation--Interior, BLM-18 (73 FR 17376, April 1, 2008); Bureau of Indian Affairs Law... Reporting System from one or more provisions of the Privacy Act because of criminal, civil,...

  15. Model Act for State Licensure of Psychologists

    Science.gov (United States)

    American Psychologist, 2011

    2011-01-01

    As APA policy, the Model Act for State Licensure of Psychologists serves as a prototype for drafting state legislation regulating the practice of psychology. State legislatures are encouraged to use the language of this document and the policies that it espouses as the model for their own state licensure laws. Inevitably each state law will…

  16. Every Student Succeeds Act and Arts Education

    Science.gov (United States)

    Kohn Bradley, Karen

    2016-01-01

    Dance educators will be pleased to know that there is new legislation at the federal level that supports arts education. Seven years after Congress was due to reauthorize the Elementary and Secondary Education Act (also known for eight + seven years as No Child Left Behind [NCLB]), the lawmakers, suddenly and surprisingly, came through with a new…

  17. Baby Steps: Learn the Signs. Act Early.

    Centers for Disease Control (CDC) Podcasts

    2008-09-22

    CDC recognized the impact of developmental disabilities and invested in a campaign to help parents measure their children's progress by monitoring how they play, learn, speak, and act. .  Created: 9/22/2008 by National Center on Birth Defects and Developmental Disabilities, Division of Human Development and Disability, Child Development Studies Team.   Date Released: 9/23/2008.

  18. 77 FR 14570 - Sunshine Act Meeting

    Science.gov (United States)

    2012-03-12

    ...-3428. STATUS: Open. MATTERS TO BE CONSIDERED: 1. Final Rule--Parts 701, 760 and 790 of NCUA's Rules and Regulations, Technical Amendments. 2. NCUA's Diversity and Inclusion Strategic Plan. 3. Quarterly Insurance... ADMINISTRATION Sunshine Act Meeting TIME AND DATE: 10 a.m., Thursday, March 15, 2012. PLACE: Board Room,...

  19. 75 FR 6553 - Compliance With NEPA

    Science.gov (United States)

    2010-02-10

    ... the preamble, NRCS adopts the interim rule published on July 13, 2009 (74 FR 33319) as final and... disturbed sites to restore and maintain the sites ecological functions and services; (2) Removing dikes and... floodplains to the extent that existed prior to the installation of such dikes and associated...

  20. Australian Radiation Protection and Nuclear Safety Act 1998. Act No 133

    International Nuclear Information System (INIS)

    A set of legislation consisting of three Acts in the field of radiation protection and nuclear safety was passed by both Houses of Parliament on 10 December 1998 and was proclaimed on 5 February 1999. Act No. 133 - Australian Radiation Protection and Nuclear Safety Act, which is a framework Law, established the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA) as the regulatory body for radiation protection and nuclear safety, in place of the Nuclear Safety Bureau. The Chief Executive Officer of ARPANSA, who is appointed by the Governor-General for a term of up to 5 years, is obliged to submit annual and quarterly reports to the Minister on the operations of the Chief Executive Officer, ARPANSA, the Council, the Radiation Health Committee and the Nuclear Safety Committee. The Council is a consultative body which examines issues relating to radiation protection and nuclear safety and advises the Chief Executive Officer on these issues as well as on the adoption of recommendations, policies and codes. The Radiation Health Committee and the Nuclear Safety Committee are to be established as advisory committees to the Chief Executive Officer or the Council. Both committees should draft national policies, codes and standards in their respective fields and review their effectiveness periodically. The second in this series of legislation, Act No. 134, Australian Radiation Protection and Nuclear Safety (License Charges) Act requires holders of both facility and source licenses to pay an annual charge, to be prescribed by the regulations. The third, Act No. 135 , Australian Radiation Protection and Nuclear Safety (Consequential Amendments) Act repeals those provisions of the 1987 Australian Nuclear Science and Technology Organisation Act which concern the Nuclear Safety Bureau, and the 1978 Environment Protection Act as a whole

  1. Australian Radiation Protection and Nuclear Safety Act 1998. Act No 133

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-01

    A set of legislation consisting of three Acts in the field of radiation protection and nuclear safety was passed by both Houses of Parliament on 10 December 1998 and was proclaimed on 5 February 1999. Act No. 133 - Australian Radiation Protection and Nuclear Safety Act, which is a framework Law, established the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA) as the regulatory body for radiation protection and nuclear safety, in place of the Nuclear Safety Bureau. The Chief Executive Officer of ARPANSA, who is appointed by the Governor-General for a term of up to 5 years, is obliged to submit annual and quarterly reports to the Minister on the operations of the Chief Executive Officer, ARPANSA, the Council, the Radiation Health Committee and the Nuclear Safety Committee. The Council is a consultative body which examines issues relating to radiation protection and nuclear safety and advises the Chief Executive Officer on these issues as well as on the adoption of recommendations, policies and codes. The Radiation Health Committee and the Nuclear Safety Committee are to be established as advisory committees to the Chief Executive Officer or the Council. Both committees should draft national policies, codes and standards in their respective fields and review their effectiveness periodically. The second in this series of legislation, Act No. 134, Australian Radiation Protection and Nuclear Safety (License Charges) Act requires holders of both facility and source licenses to pay an annual charge, to be prescribed by the regulations. The third, Act No. 135 , Australian Radiation Protection and Nuclear Safety (Consequential Amendments) Act repeals those provisions of the 1987 Australian Nuclear Science and Technology Organisation Act which concern the Nuclear Safety Bureau, and the 1978 Environment Protection Act as a whole

  2. Distinguishing early-acting inbreeding depression from late-acting ovar-ian self-incompatibility

    OpenAIRE

    Yiqi Hao; Xinfeng Zhao

    2011-01-01

    Reduced seed yields after self-pollination are generally thought to be induced by early-acting in-breeding depression and self-incompatibility. Early-acting inbreeding depression occurs strictly post-zygoti- cally, and leads to the abortion of progeny that are homozygous for deleterious recessive alleles at an early stage of seed maturation. Late-acting ovarian self-incompatibility, on the other hand, may be either pre- or post-zygotic, and usually only one locus is responsible for the reject...

  3. The Nuclear Waste Policy Act, as amended with appropriations acts appended

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    The Nuclear Waste Policy Act of 1982 provides for the development of repositories for the disposal of high-level radioactive waste and spent nuclear fuel, to establish a program of research, development and demonstration regarding the disposal of high-level radioactive waste and spent nuclear fuel. Titles 1 and 2 cover these subjects. Also included in this Act are: Title 3: Other provisions relating to radioactive waste; Title 4: Nuclear waste negotiation; Title 5: Nuclear waste technical review board; and Title 6: High-level radioactive waste. An appendix contains excerpts from appropriations acts from fiscal year 1984--1994.

  4. 21 CFR 1230.2 - Scope of the act.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Scope of the act. 1230.2 Section 1230.2 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS... CAUSTIC POISON ACT General Provisions § 1230.2 Scope of the act. The provisions of the act apply to...

  5. 21 CFR 1210.2 - Scope of act.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Scope of act. 1210.2 Section 1210.2 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER... MILK ACT General Provisions § 1210.2 Scope of act. The provisions of the act apply to all milk...

  6. The Environmental Education Act of 1970: Success or Failure?

    Science.gov (United States)

    Marcus, Melvin G.

    1984-01-01

    Identifies and interprets several problems that beset environmental education (EE) and the Office of Environmental Education (OEE). Areas addressed include Public Law 91-516 (Environmental Education Act) and the OEE, problems related to implementing the act, funding, misinterpretation of the act's intent, the act's identity, and the status of EE…

  7. 32 CFR 806b.4 - Privacy Act complaints.

    Science.gov (United States)

    2010-07-01

    ... unique system complaints through the respective component chain of command. (b) For Privacy Act... complaints or allegations of Privacy Act violations through the appropriate base or Major Command Privacy Act office, to the local systems manager. The base or Major Command Privacy Act officer directs the...

  8. 48 CFR 50.205-1 - SAFETY Act Considerations.

    Science.gov (United States)

    2010-10-01

    ... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Support Anti-terrorism by..., detect, identify, or deter acts of terrorism or limit the harm such acts might cause, and may be... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false SAFETY Act...

  9. 45 CFR 503.1 - Definitions-Privacy Act.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Definitions-Privacy Act. 503.1 Section 503.1... THE UNITED STATES, DEPARTMENT OF JUSTICE RULES OF PRACTICE PRIVACY ACT AND GOVERNMENT IN THE SUNSHINE REGULATIONS Privacy Act Regulations § 503.1 Definitions—Privacy Act. For the purpose of this part:...

  10. 25 CFR 700.259 - Records subject to Privacy Act.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Records subject to Privacy Act. 700.259 Section 700.259 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Privacy Act § 700.259 Records subject to Privacy Act. The Privacy Act applies to all “records” as...

  11. 45 CFR 503.2 - General policies-Privacy Act.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false General policies-Privacy Act. 503.2 Section 503.2... THE UNITED STATES, DEPARTMENT OF JUSTICE RULES OF PRACTICE PRIVACY ACT AND GOVERNMENT IN THE SUNSHINE REGULATIONS Privacy Act Regulations § 503.2 General policies—Privacy Act. The Commission will protect...

  12. 76 FR 38330 - Implementation of Revised Lacey Act Provisions

    Science.gov (United States)

    2011-06-30

    ... proposed rulemaking. SUMMARY: The Food, Conservation and Energy Act of 2008 amended the Lacey Act to... plants. The Food, Conservation and Energy Act of 2008, effective May 22, 2008, amended the Lacey Act by... which the plant was harvested. On October 8, 2008, we published a notice in the Federal Register (73...

  13. 76 FR 38742 - Prompt Payment Interest Rate; Contract Disputes Act

    Science.gov (United States)

    2011-07-01

    ... interest penalty. 31 U.S.C. 3902(a). The Contract Disputes Act of 1978, Sec. 12, Public Law 95-563, 92 Stat... Fiscal Service Prompt Payment Interest Rate; Contract Disputes Act AGENCY: Bureau of the Public Debt... under section 12 of the Contract Disputes Act of 1978 and under the Prompt Payment Act. Under the...

  14. The New Findings Made in Speech Act Theory

    Institute of Scientific and Technical Information of China (English)

    管彦波

    2007-01-01

    Through carefully studying the theory of speech acts and the literature concerning it,the author made some new findings which reflects in three aspects:the similarities and differences in Chinese and English in expressing the same speech act,the relations between different types of speech acts and the correspondence between sentenee sets and sets of speech acts.

  15. Investigating Pragmatics of Complaint Speech Acts in English and Chinese

    Institute of Scientific and Technical Information of China (English)

    张颖卉; 李尚哲

    2013-01-01

    The speech act of complaint is an important research subject of pragmatics, which is worthy of research among speech acts. With the development of research into speech acts, some scholars have performed investigations of complaints ,but they have done little work on Chinese language complaints. Therefore, it is necessary to make a further study on complaint as a speech act in Chinese. This thesis is based on speech act theory and the politeness principle as an empirical study of the speech act of com-plaint in Chinese. It aims to provide a more complete and comprehensive result of participant production of the speech act of complaint.

  16. Wave Forces Acting on Vertical Walls

    Institute of Scientific and Technical Information of China (English)

    LI Ben-xia; YU Yu-xiu; YU Xi-ping

    2008-01-01

    Regular and irregular wave forces acting on vertical walls are studied by a previously developed numerical model. The computed wave forces are compared with the available experimental data to verify the numerical model, and satisfactory agreements are obtained. The variation of wave forces with incident angles and the shape of simultaneous pressure distribution are investigated, and the comparisons between numerical results and Goda's predictions are also carried out. It is concluded that the maximum wave forces acting on the unit length of vertical wall is often induced by the obliquely incident waves instead of normally incident waves, while Goda's formula may be inapplicable for oblique wave incidence. The shape of simultaneous pressure distribution is not significantly influenced by incident angles, and it can be favorably predicted by Goda's formula. When regular wave heights are taken as the same as irregular wave height H1%, the irregular wave forces Ph,1% are slightly larger than regular wave forces in most cases.

  17. Consumer protection act for digital products

    Science.gov (United States)

    Hampel, Viktor E.

    1996-03-01

    This report proposes a `Consumer Protection Act for Digital Products' to support electronic commerce and to control the increasing abuse and lack of security on the national information highways. Patterned after the `Food and Drug Act of 1906 (21 USC)' and subsequent legislation, a new agency similar to that of the FDA would have the authority `to develop administrative policy with regard to the safety, effectiveness, and labeling of digital products and their communications for human use, and to review and evaluate new applications of such products.' Specifically, it is proposed that standards, originally developed by the defense industry for the labeling, enveloping, and authentication of digital products delivered to the Government, be extended to promote global electronic commerce by protecting the intellectual property rights of producers, establishing their liability for the end-use of digital products, and give consumers means for informed decision making and purchase.

  18. MELCOR accident analysis for ARIES-ACT

    Energy Technology Data Exchange (ETDEWEB)

    Paul W. Humrickhouse; Brad J. Merrill

    2012-08-01

    We model a loss of flow accident (LOFA) in the ARIES-ACT1 tokamak design. ARIES-ACT1 features an advanced SiC blanket with LiPb as coolant and breeder, a helium cooled steel structural ring and tungsten divertors, a thin-walled, helium cooled vacuum vessel, and a room temperature water-cooled shield outside the vacuum vessel. The water heat transfer system is designed to remove heat by natural circulation during a LOFA. The MELCOR model uses time-dependent decay heats for each component determined by 1-D modeling. The MELCOR model shows that, despite periodic boiling of the water coolant, that structures are kept adequately cool by the passive safety system.

  19. New Danish Company Act on Shareholders' Agreements

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2011-01-01

    . The substantial elements in many agreements are clauses on (1) voting for board candidates, (2) voting for dividends of certain proportions, and (3) first refusal rights, respectively, call options for shares in the company. Such clauses are at the very roots of corporate law, dealing with the shareholders’ (1......) organizational rights, (2) financial rights, and (3) rights of disposal, or in plainer words, the corporate (1) power, (2) money, and (3) exit. If a shareholders’ agreement is thoroughly kept and respected by all parties, both in the way they vote at general assemblies and in the way they act when wishing......Section 82 of the Danish Company Act, in force from 1 March 2010, provides that ‘Shareholders’ agreements are neither binding on the company nor on decisions taken by the general assembly’. This has far-reaching consequences for shareholders’ agreements, also for already existing agreements...

  20. 77 FR 15835 - Privacy Act of 1974: Revision of Privacy Act System of Records

    Science.gov (United States)

    2012-03-16

    ... amending its Privacy Act System of Records Notice, which was previously published at 74 FR 14890 (April 1..., Omaha, NB 68134. Springfield Branch Office 830 East Primrose, Suite 101, Springfield, MO 65807-5254....

  1. Radiation Safety Act 1975 - No 44 of 1975

    International Nuclear Information System (INIS)

    This Act regulates the use of radioactive substances and irradiating apparatus, including particle accelerators as well as certain specified electronic products. The Act lays down a licensing and registration system for such substances and apparatus; it sets up a Radiological Council to administer the Act and to advise the Minister responsible for public health on matters of radiation safety. The radioactive Substances Act 1954 and the Amending Acts of 1960 and 1964 are repealed. (NEA)

  2. Speech Acts In President Barack Obama Victory Speech 2012

    OpenAIRE

    Januarini, Erna

    2016-01-01

    In the thesis, entitled Speech Acts In President Barack Obama's Victory Speech 2012. The author analyzes the illocutionary acts and direct and indirect speech acts and by Barack Obama as a speaker based on representative, directive, expressive, commissive, and declaration. The purpose of this thesis is to find the types of illocutionary acts and direct and indirect speech acts and in Barack Obama's victory speech 2012. In writing this thesis, the author uses a qualitative method from Huberman...

  3. Speech act theory and New Testament exegesis

    OpenAIRE

    J. Botha

    1991-01-01

    Speech act theory offers New Testament exegesis some additional ways and means of approaching the text of the New Testament. This, the second in a series of two articles that make a plea for the continued utilisation and application of this theory to the text of the New Testament, deals with some of the possibilities and potential this theory holds for reading biblical texts. Advantages are pointed out and a few suggestions for the future proposed.

  4. Speech act theory and New Testament exegesis

    Directory of Open Access Journals (Sweden)

    J. Botha

    1991-01-01

    Full Text Available Speech act theory offers New Testament exegesis some additional ways and means of approaching the text of the New Testament. This, the second in a series of two articles that make a plea for the continued utilisation and application of this theory to the text of the New Testament, deals with some of the possibilities and potential this theory holds for reading biblical texts. Advantages are pointed out and a few suggestions for the future proposed.

  5. Interpreting the Computer Fraud and Abuse Act

    OpenAIRE

    Lee Goldman

    2012-01-01

    Computers play an integral role in today’s society.  While computers provide many benefits, they are increasingly used as tools for wrongdoing, causing estimated losses of billions of dollars each year. Computer hackers can, among other things, fraudulently alter accounts, steal business or personal information, and corrupt or disable computer systems.  Congress enacted and has repeatedly amended the Computer Fraud and Abuse Act (“CFAA”) to combat the increasing proliferation of computer crim...

  6. Pulmonary dendritic cells: thinking globally, acting locally

    OpenAIRE

    Randall, Troy D.

    2010-01-01

    The phrase “think globally, act locally” was coined in the early 1970s and directed individuals to clean up their local environment with the ultimate goal of improving the health of the entire planet. Several recent studies indicate that similar considerations apply to the immune system, in which small numbers of leukocytes, such as pulmonary dendritic cells, can modify the local immune environment in the lung and promote a positive outcome for the organism.

  7. Trifluoromethyl acting as stopper in [2]rotaxane

    KAUST Repository

    Dasgupta, Suvankar

    2012-07-24

    A modified dumbbell obtained by replacing one of the phenyl groups of the dibenzylammonium with a strong electron-withdrawing trifluoromethyl group templated the synthesis of the smallest [2]rotaxane reported so far. The trifluoromethyl group not only enhances the templating effect of the dumbbell but also acts as the stopper to prevent dethreading of a [20]crown ether macrocycle. © 2012 The Royal Society of Chemistry.

  8. The making of the Single European Act

    OpenAIRE

    Budden, Philip Marcus.

    1994-01-01

    This thesis is a contemporary history of one episode in the United Kingdom's experience of the European Community (EC). It charts the making of the Single European Act (SEA) from its early 1980s' origins, through the bargaining process of the Dooge Committee and 1985 intergovernmental conference (IGC), to the SEA itself. By studying the origins of a specific treaty, the thesis analyses the impact of EC membership on one west European nation state and places the histor...

  9. Clean Water Act (excluding Section 404)

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-15

    This Reference Book contains a current copy of the Clean Water Act (excluding Section 404) and those regulations that implement the statutes and appear to be most relevant to US Department of Energy (DOE) activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  10. A perspective on the PCPNDT Act

    Directory of Open Access Journals (Sweden)

    A Murali Mohan Patnaik

    2012-01-01

    Full Text Available Background: An important modern diagnostic tool, used for monitoring pregnancy and genetic defects; the ultrasound machine, has also become a selective killer of the female child. The male child preference in India was responsible for female infanticides in the past. With easy availability and accessibility of USG, a shift has occurred from infanticide to feticide, although female infanticides still continue. In the process doctors are blamed as "merchants of death". Peeved and pressed by national and internal agencies for the declining female child ratio (0-6 years, the Government of India reacted by enacting a stringent PC-PNDT Act almost solely aimed at doctors to prevent them from advertising and disclosing the sex of the fetus to the pregnant woman or her relatives. Since the enactment, hundreds of cases have been launched against the doctors. Aims: 1. In order to stand up to the law important sections and rules of the PC-PNDT Act have been analyzed for the benefit of our colleagues. 2. The Indian legal system rests the "burden of proof" on the prosecution. In two sections of The Act, these have been done away with. Instead, the accused doctor has to prove himself innocent. Therefore a demand has been made to make suitable amendments to The Act in this regard. 3. The inclusion of column numbers 9-19 in the form ′F′ is not relevant for USG clinics/ imaging centers; inaccurate filling of which may attract a prison sentence of 3 years. This irrelevance has to be deleted. 4. Some suggestions.

  11. Team management: an alternative to acting directorship.

    Science.gov (United States)

    Hodson, K E; Ryan, M E; Judy, M; Foster, S L

    1990-01-01

    A sudden absence of leadership due to unexpected illness, death, or resignation can seriously weaken an organization. Orderly administrative transition was believed to be necessary by those confronting a sudden leadership void. A team management administrative approach was proposed in response to an urgent and complex problem. Results of an evaluation of the team at the end of 1 year of leadership are presented. Team management is documented as a viable alternative to a one person acting director in an academic setting.

  12. RE:ACT Adult Protection Program

    OpenAIRE

    Farquharson, Kristen

    2012-01-01

    This video clip comprises one of the 5 presentations of the PANEL SESSION: “The Front Line – Home Care Providers” held at the 21st Annual John K. Friesen Conference, "Innovations in Home Care: A Public Policy Perspective," MAY 16-17, 2012, Vancouver, BC. Presented by Kristen Farquharson, Manager, RE:ACT Adult Protection Program & Patient Quality Care Office, Vancouver Coastal Health. It is well known that jurisdictions with more comprehensive and integrated home care delivery syst...

  13. FATCA (Foreign Account Tax Compliance Act)

    OpenAIRE

    Lojíková, Andrea

    2012-01-01

    This bachelor's work is about FATCA (Foreign Accoun Tax Compliance Act), which is a new american taxation law, which was oficially signed, by United States of America, into law on March 2010 to confine tax evasion. My main aim was to define how FATCA works, clarity about strategy, the challenge of customer identification and what FATCA is all about. There are aslo defined some payments of foreign financial institutions and rules for withholding agents.

  14. Aviation, Carbon, and the Clean Air Act

    OpenAIRE

    Richardson, Nathan

    2012-01-01

    This paper explores the policy options available to the United States for regulating greenhouse gas emissions from aircraft under existing law: the Clean Air Act (CAA). Europe has unilaterally and controversially moved to include aviation emissions in its Emissions Trading System. The United States can, however, allow its airlines to escape this requirement by imposing “equivalent” regulation. U.S. aviation emissions rules could also have significant environmental benefits and would limit dom...

  15. Staff turnover in statewide implementation of ACT: relationship with ACT fidelity and other team characteristics

    OpenAIRE

    Rollins, Angela L.; Salyers, Michelle P.; Tsai, Jack; Lydick, Jennifer M.

    2010-01-01

    Staff turnover on assertive community treatment (ACT) teams is a poorly understood phenomenon. This study examined annual turnover and fidelity data collected in a statewide implementation of ACT over a 5-year period. Mean annual staff turnover across all observations was 30.0%. Turnover was negatively correlated with overall fidelity at Year 1 and 3. The team approach fidelity item was negatively correlated with staff turnover at Year 3. For 13 teams with 3 years of follow-up data, turnover ...

  16. 17 CFR 270.0-10 - Small entities under the Investment Company Act for purposes of the Regulatory Flexibility Act.

    Science.gov (United States)

    2010-04-01

    ... Investment Company Act for purposes of the Regulatory Flexibility Act. 270.0-10 Section 270.0-10 Commodity..., INVESTMENT COMPANY ACT OF 1940 § 270.0-10 Small entities under the Investment Company Act for purposes of the... defined for purposes of a particular rulemaking, the term small business or small organization...

  17. 23 CFR 633.211 - Implementation of the Clean Air Act and the Federal Water Pollution Control Act.

    Science.gov (United States)

    2010-04-01

    ... Pollution Control Act. Pursuant to regulations of the Environmental Protection Agency (40 CFR part 15) implementing requirements with respect to the Clean Air Act and the Federal Water Pollution Control Act are... Water Pollution Control Act. 633.211 Section 633.211 Highways FEDERAL HIGHWAY ADMINISTRATION,...

  18. 29 CFR 1620.27 - Relationship to the Equal Pay Act of title VII of the Civil Rights Act.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Relationship to the Equal Pay Act of title VII of the Civil... OPPORTUNITY COMMISSION THE EQUAL PAY ACT § 1620.27 Relationship to the Equal Pay Act of title VII of the Civil Rights Act. (a) In situations where the jurisdictional prerequisites of both the EPA and title VII of...

  19. 77 FR 61027 - Notice of Lodging of Proposed Consent Decree Under the Clean Water Act and Safe Drinking Water Act

    Science.gov (United States)

    2012-10-05

    ... of Lodging of Proposed Consent Decree Under the Clean Water Act and Safe Drinking Water Act On... Clean Water Act and Safe Drinking Water Act at mobile home parks operated by defendants in Pennsylvania, Delaware and Virginia. The defendants treat sewage and provide drinking water at a number of its...

  20. 29 CFR 1614.407 - Civil action: Title VII, Age Discrimination in Employment Act and Rehabilitation Act.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Civil action: Title VII, Age Discrimination in Employment Act and Rehabilitation Act. 1614.407 Section 1614.407 Labor Regulations Relating to Labor (Continued... Actions § 1614.407 Civil action: Title VII, Age Discrimination in Employment Act and Rehabilitation Act....

  1. 19 CFR 147.23 - Compliance with Plant Quarantine Act and Federal Food, Drug, and Cosmetic Act.

    Science.gov (United States)

    2010-04-01

    ... Food, Drug, and Cosmetic Act. 147.23 Section 147.23 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... Laws § 147.23 Compliance with Plant Quarantine Act and Federal Food, Drug, and Cosmetic Act. (a) Plant... the plant quarantine regulations. (b) Federal Food, Drug, and Cosmetic Act. The entry of food...

  2. 43 CFR Appendix F to Part 2 - Mineral Leasing Act and Mineral Leasing Act for Acquired Lands-Special Rules

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Mineral Leasing Act and Mineral Leasing... 2—Mineral Leasing Act and Mineral Leasing Act for Acquired Lands—Special Rules (a) Definitions. As... conduct coal exploration operations on land subject to the Mineral Leasing Act, under 30 U.S.C. 201(b),...

  3. 75 FR 61169 - Privacy Act; Notification of a New Privacy Act System of Records, Homeless Families Impact Study...

    Science.gov (United States)

    2010-10-04

    ... will backup the data on a regular basis to safeguard against system failures or disasters. Only... URBAN DEVELOPMENT Privacy Act; Notification of a New Privacy Act System of Records, Homeless Families... New Privacy Act System of Records (SORN). SUMMARY: HUD proposes to establish a new Privacy Act of...

  4. 75 FR 11560 - Notice of Lodging of Consent Decree Under the Clean Water Act and Clean Air Act

    Science.gov (United States)

    2010-03-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Notice of Lodging of Consent Decree Under the Clean Water Act and Clean Air Act Notice is hereby given that... violations of the Clean Water Act, 33 U.S.C. 1251 et seq., and the Clean Air Act, 42 U.S.C. 7401 et seq....

  5. 78 FR 70960 - Notice of Lodging of Consent Decree Under the Clean Air Act, Clean Water Act, and the Resource...

    Science.gov (United States)

    2013-11-27

    ... of Lodging of Consent Decree Under the Clean Air Act, Clean Water Act, and the Resource Conservation... the United States and the State of Illinois under the Clean Air Act, the Clean Water Act, the Resource... and Natural Resource Division. BILLING CODE 4410-15-P...

  6. Long-Acting Growth Hormone: An Update.

    Science.gov (United States)

    Saenger, Paul H; Mejia-Corletto, Jorge

    2016-01-01

    After the introduction of recombinant human growth hormone (rhGH) in 1985, a myriad of children and adults have benefited from its growth-promoting and metabolic effects. Nowadays, current therapeutic regimens rely on daily subcutaneous GH injections that could be burdensome and inconvenient to pediatric patients. As expected with any long-term parenteral pharmacological treatment, these daily regimens may promote nonadherence, poor compliance, treatment abandonment and/or suboptimal clinical outcomes. In order to improve patient and caregiver acceptance of proposed regimens, simplified dosing schedules could potentially aid in reducing poor compliance and maximize the therapeutic end results. Long-acting GH formulations have been designed and perfected over the last two decades, and currently there are several formulations in advanced stages of research as a reasonable attempt to improve patient's adherence to GH treatment. A long-acting GH preparation allowing for reduced injection frequency is likely to improve treatment adherence and to decrease the distress and inconvenience associated with daily injections. This review presents an update about the status of current and recent efforts that have enabled the formulation of sustained-release, long-acting rhGH as it has been longed for many years in the pediatric endocrinology field.

  7. Long-acting preparations of exenatide

    Directory of Open Access Journals (Sweden)

    Cai Y

    2013-09-01

    Full Text Available Yunpeng Cai,1,2,* Liangming Wei,3,* Liuqing Ma,2 Xiwen Huang,2 Anqi Tao,2 Zhenguo Liu,1 Weien Yuan1,2 1Department of Neurology, Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine, 2School of Pharmacy, Shanghai JiaoTong University, 3Key Laboratory for Thin Film and Microfabrication Technology, Ministry of Education, Research Institute of Micro/Nanometer Science and Technology, Shanghai JiaoTong University, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: Exenatide has been widely used for the treatment of type 2 diabetes mellitus. However, its short plasma half-life of 2.4 hours has limited its clinical application. The exenatide products on the market, twice-daily Byetta™ and once-weekly Bydureon™ (both Amylin Pharmaceuticals, San Diego, CA, USA, are still not perfect. Many researchers have attempted to prolong the acting time of exenatide by preparing sustained-release dosage forms, modifying its structure, gene therapies, and other means. This review summarizes recent advances in long-acting exenatide preparations. Keywords: exendin-4, diabetes mellitus type 2, sustained release, long acting, extended release, microsphere

  8. Pay Equity Act, 17 May 1988.

    Science.gov (United States)

    1988-01-01

    This document contains major provisions of the 1988 Pay Equity Act of Prince Edward Island, Canada. (Nova Scotia enacted similar legislation in 1988.) This act defines "female-dominated class" or "male-dominated class" as a class with 60% or more female or male incumbents, respectively. The objective of this act is to achieve pay equity among public sector employers and employees by identifying systemic gender discrimination through a comparison of the relative wages and value of the work performed by female- and male-dominated classes. The value of work is to be determined by considering the skill, effort, and responsibility required by the work as well as the conditions under which it is performed. A difference in wages between a female- and male-dominated class performing work of equal or comparable value can be justified by a formal performance appraisal system or formal seniority system that does not discriminate on the basis of gender or by a skills shortage which requires a temporary inflation in wages to attract workers for a certain position. No wages shall be reduced to implement pay equity. Implementation of pay equity will include the work of bargaining agents to achieve agreement on salient points. Pay equity may be implemented in four stages over a period of 24 months. PMID:12289286

  9. THE CHILD JUSTICE ACT: PROCEDURAL SENTENCING ISSUES

    Directory of Open Access Journals (Sweden)

    Stephan S Terblanche

    2013-04-01

    Full Text Available In this contribution a number of procedural issues related to the sentencing of child offenders and emanating from the Child Justice Act 75 of 2008 are considered in some detail. As a general rule, the Act requires pre-sentence reports to be obtained from probation officers before sentencing any child offender, with only a limited number of exceptions. The article argues that the peremptory nature of the Act means that a probation report is always required, even if reports by other experts are also available. The exceptions are limited to instances other than those where the child offender is sentenced to any form of imprisonment or to residence in a care centre. The article addresses the question of whether or not the reference to imprisonment includes alternative imprisonment which is imposed only as an alternative to a fine. It suggests that alternative imprisonment should, generally, not be imposed on child offenders. When an exception is not prevented because of the sentence, a pre-sentence report may be dispensed with only when the offence is a schedule-1 offence (the least serious class of offences or when obtaining a report would prejudice the child. It is argued that these exceptions are likely to occur rather rarely. A final aspect of the Act’s provisions on pre-sentence reports is the requirement that reasons be given for a departure from the recommendations in a pre-sentence report. This requirement merely confirms the status quo.The Act permits the prosecutor to provide the court with a victim impact statement. Such a statement is defined in the Act. It is a sworn statement by a victim or someone authorised by the victim explaining the consequences to the victim of the commission of the crime. The article also addresses the issue of whether or not the child justice court might mero motu obtain a victim impact statement when the prosecution does not do so.Finally, the article addresses appeals against and reviews of the trial

  10. The Pathology Laboratory Act 2007 explained.

    Science.gov (United States)

    Looi, Lai-Meng

    2008-06-01

    The past century has seen tremendous changes in the scope and practice of pathology laboratories in tandem with the development of the medical services in Malaysia. Major progress was made in the areas of training and specialization of pathologists and laboratory technical staff. Today the pathology laboratory services have entered the International arena, and are propelled along the wave of globalization. Many new challenges have emerged as have new players in the field. Landmark developments over the past decade include the establishment of national quality assurance programmes, the mushrooming of private pathology laboratories, the establishment of a National Accreditation Standard for medical testing laboratories based on ISO 15189, and the passing of the Pathology Laboratory Act in Parliament in mid-2007. The Pathology Laboratory Act 2007 seeks to ensure that the pathology laboratory is accountable to the public, meets required standards of practice, participates in Quality Assurance programmes, is run by qualified staff, complies with safety requirements and is subject to continuous audit. The Act is applicable to all private laboratories (stand alone or hospital) and laboratories in statutory bodies (Universities, foundations). It is not applicable to public laboratories (established and operated by the government) and side-room laboratories established in clinics of registered medical or dental practitioners for their own patients (tests as in the First and Second Schedules respectively). Tests of the Third Schedule (home test blood glucose, urine glucose, urine pregnancy test) are also exempted. The Act has 13 Parts and provides for control of the pathology laboratory through approval (to establish and maintain) and licensing (to operate or provide). The approval or license may only be issued to a sole proprietor, partnership or body corporate, and then only if the entity includes a registered medical practitioner. Details of personnel qualifications and

  11. The Polish Budget Act for 2016: Legal Issues

    Directory of Open Access Journals (Sweden)

    Andrzej Borodo

    2016-06-01

    Full Text Available The article presents the legal content and system of the 2016 Budget Act and the legal significance of its regulations. The Budget Act for 2016 contains three parts: the state budget (general budget, complementary budgets, other legal provisions. The state revenues, expenditure, expenses, salaries, rates of some state levies are determined in the Budget Act. The regulations of the Budget Act relate to the financial activity of government and other parts of the state. The complex Budget Act contains provisions resulting from the many legal acts.

  12. An experimental characterization of human torso motion

    Science.gov (United States)

    Cafolla, Daniele; Chen, I.-Ming; Ceccarelli, Marco

    2015-12-01

    The torso plays an important role in the human-like operation of humanoids. In this paper, a method is proposed to analyze the behavior of the human torso by using inertial and magnetic sensing tools. Experiments are conducted to characterize the motion performance of the human torso during daily routine operations. Furthermore, the forces acting on the human body during these operations are evaluated to design and validate the performance of a humanoid robot.

  13. Thinking globally, acting locally: Women activists’ accounts

    Directory of Open Access Journals (Sweden)

    Alldred Pam

    2003-01-01

    Full Text Available This paper intends to describe the range of forms women’s resistance to globalisation takes, emphasising diverse strategies from everyday acts, the development of practical alternative resources, organising in women’s groups or trades unions, mass demonstrations and symbolic defiance. Recognising that it is the women of the South, in particular, who bear the brunt of the impact of neoliberal ‘free market’ economic policies, it hoped to be sensitive to the struggles for survival that might frame the urgency of resistance amongst women of the South, and make links with some of the strategies of activist women in the more privileged North.

  14. Team management: an alternative to acting directorship.

    Science.gov (United States)

    Hodson, K E; Ryan, M E; Judy, M; Foster, S L

    1990-01-01

    A sudden absence of leadership due to unexpected illness, death, or resignation can seriously weaken an organization. Orderly administrative transition was believed to be necessary by those confronting a sudden leadership void. A team management administrative approach was proposed in response to an urgent and complex problem. Results of an evaluation of the team at the end of 1 year of leadership are presented. Team management is documented as a viable alternative to a one person acting director in an academic setting. PMID:2377327

  15. ACTS for distance education in developing countries

    Science.gov (United States)

    Kalu, A.; Ventre, G.

    1995-08-01

    The need for electrical energy supply in the rural communities of developing countries has been well documented. Equally well known is the potential for photovoltaic in cost effectively meeting this need. A major impediment to fulfilling the need is the lack of indigenous personnel with a knowledgeof photovoltaic systems, and the associated infrastructure required to implement project. Various delivery schemes for providing the needed training to developing countries personnel have been investigated. Various train methods and programs that have been employed to remedy the problem have had significant drawbacks in terms of cost, consistency, impact, reach, and sustainability. The hypothesis to be tested in this project posits that satellite-based distance education using ACTS technologies can overcome these impediments. The purpose of the project is to investigate the applicability of the ACTS satellite in providing distance education in photovoltaic systems to developing countries and rural communities. An evaluation of the cost effectiveness of using ACTS unique technologies to overcome identified problems shall be done. The limitations of ACTS in surmounting distance education problems in developing countries shall be investigated. This project will, furthermore, provide training to Savannah State College faculty in photovoltaic (PV) systems and in distance education configurations and models. It will also produce training materials adequate for use in PV training programs via distance education. Savannah State College will, as a consequence become well equipped to play a leading role in the training of minority populations in photovoltaic systems and other renewables through its Center for Advanced Water Technology and Energy Systems. This communication provides the project outline including the specific issues that will be investigated during the project. Also presented i the project design which covers the participations of the various components of a network

  16. Legal consideration on draft water act

    OpenAIRE

    Ayanoğlu, Sedat; Yıldırım, Hülya Deniz

    2014-01-01

    Legal consideration on draft  water actAbstract: Very old regulations are found on water which is an indispensible natural spring and a need for the continuation of life.  Nowadays the importance of water law is increasing as a new branch of law. Although recognition of the right of ownership on springs, this branch of law as a sub branch of  law of natural springs has a character of public law  due to the importance of the subject which is regulated by it. Since water has different propertie...

  17. The Jerusalem Temple in Luke-Acts

    Directory of Open Access Journals (Sweden)

    N.H. Taylor

    2004-11-01

    Full Text Available Luke-Acts was written during the period after the destruction of the second temple, when, for most Jews, hopes for future restoration were conceived largely in terms of rebuilding the temple and city of Jerusalem and resuming the cultic life associated therewith. Against this background Luke poses an alternative vision, in which the divine presence associated previously with the [foreign font omitted] is seen no longer as localised but as dispersed. The Holy Spirit manifested in the life and expansion of the Church transcends and supersedes the notion of sacred space associated with the Zion traditions.

  18. Deep Acting and Surface Acting Scale (DASAS – Adaptation of the metod and preliminary psychometric properties

    Directory of Open Access Journals (Sweden)

    Maria Finogenow

    2015-07-01

    Full Text Available Background: This article presents the results of the study on the Polish version of the revised Emotional Labor Scale (ELS, developed by Lee and Brotheridge. The ELS measures deep acting and 2 aspects of surface acting (hiding feelings and faking emotions. Material and Methods: Psychometric characteristics of the Polish version of the ELS, named Deep Acting and Surface Acting Scale (DASAS, were analyzed in the preliminary study on 332 people working in various service professions. We verified factor structure of the scale, its reliability, and construct validity (that is, the relationships between its subscales and other measures of workplace functioning. Results: The results indicated that the DASAS has good psychometric properties which are comparable with the characteristics of the original scale. We replicated a 3-factor structure of the scale and confirmed its satisfying internal consistency and construct validity. Conclusions: The preliminary findings suggest that the DASAS is an adequate measure of deep and surface acting. Med Pr 2015;66(3:359–371

  19. The Prescription Drug Marketing Act of 1987.

    Science.gov (United States)

    Greenberg, R B

    1988-10-01

    The Prescription Drug Marketing Act of 1987 is described, and its implications for hospitals and other health-care entities are discussed. The act, which became effective on July 21, 1988, is intended to reduce public health risks from adulterated, misbranded, and counterfeit drug products that enter the marketplace through drug diversion. The law provides that prescription drug products manufactured in the United States and exported can no longer be reimported, except by the product's manufacturer. It also establishes restrictions on sales of prescription drug products and samples. Samples of prescription drug products may be distributed only if a licensed prescriber requests them. Other distribution channels for samples specified in the law are permissible, provided records are maintained. Under the law, wholesale distributors must be licensed by the state and meet uniform standards. Penalties for violations of the law are also identified. According to FDA's advisory guidelines on the statute, the law will permit hospitals to return drug products, provided the return is made to the manufacturer or wholesaler and provided written notice is secured that the goods were received (for manufacturers) or the goods were destroyed or returned to the manufacturer (for wholesalers). The final chapter on drug diversion must await issuance of final FDA regulations. PMID:3228083

  20. Genetic Information Nondiscrimination Act. Final rule.

    Science.gov (United States)

    2016-05-17

    The Equal Employment Opportunity Commission (EEOC or Commission) is issuing a final rule to amend the regulations implementing Title II of the Genetic Information Nondiscrimination Act of 2008 as they relate to employer-sponsored wellness programs. This rule addresses the extent to which an employer may offer an inducement to an employee for the employee's spouse to provide information about the spouse's manifestation of disease or disorder as part of a health risk assessment (HRA) administered in connection with an employer-sponsored wellness program. Several technical changes to the existing regulations are included. Published elsewhere in this issue of the Federal Register, the EEOC also issued a final rule to amend the regulations and interpretive guidance implementing Title I of the Americans with Disabilities Act (ADA) that addresses the extent to which employers may use incentives to encourage employees to participate in wellness programs that ask them to respond to disability-related inquiries and/or undergo medical examinations. PMID:27192741

  1. Clean Water Act (Section 404) and Rivers and Harbors Act (Sections 9 and 10)

    International Nuclear Information System (INIS)

    This Reference Book contains a current copy of the Clean Water Act (Section 404) and the Rivers and Harbors Act (Sections 9 and 10) and those regulations that implement those sections of the statutes and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, IH-231 (FTS 896-2609 or Commercial 202/586-2609)

  2. Characterization Plan for Soils Around Drain Line PLA-100115

    Energy Technology Data Exchange (ETDEWEB)

    D. Shanklin

    2006-05-24

    This Characterization Plan supports the Hazardous Waste Management Act/Resource Conservation and Recovery Act (HWMA/RCRA) closure of soils that may have been contaminated by releases from drain line PLA-100115, located within the Idaho Nuclear Technology and Engineering Center at the Idaho National Laboratory Site. The requirements to address the closure of soils contaminated by a potential release from this line in a characterization plan was identified in the "HWMA/RCRA Less Than 90-day Generator Closure Report for the VES-SFE-126."

  3. 77 FR 67329 - Information Collection: Agricultural Foreign Investment Disclosure Act

    Science.gov (United States)

    2012-11-09

    ...; ] DEPARTMENT OF AGRICULTURE Farm Service Agency Information Collection: Agricultural Foreign Investment... collection associated with the Agricultural Foreign Investment Disclosure Act (AFIDA) of 1978. DATES: We will... Foreign Investment Disclosure Act (AFIDA) Program Manager, Natural Resources Analysis Group, Economic...

  4. 78 FR 14281 - Privacy Act of 1974; System of Records

    Science.gov (United States)

    2013-03-05

    ..., Defense Finance and Accounting Service, Freedom of Information/Privacy Act Program Manager, Corporate..., 71 FR 14182). * * * * * Changes: System Identifier: Delete entry and replace with ``T7344... Defense Finance and Accounting Service, Freedom of Information/Privacy Act Program Manager, ]...

  5. 29 CFR 1980.102 - Obligations and prohibited acts.

    Science.gov (United States)

    2010-07-01

    ... THE CORPORATE AND CRIMINAL FRAUD ACCOUNTABILITY ACT OF 2002, TITLE VIII OF THE SARBANES-OXLEY ACT OF... Securities and Exchange Commission, or any provision of Federal law relating to fraud against shareholders... fraud against shareholders....

  6. Plainer Legal Language: Definitions and Requirements in Acts.

    Science.gov (United States)

    Jordan, Michael P.

    1994-01-01

    Explores some of the stylistic complexities of definitions and requirements in a Canadian provincial act. Generates and justifies 15 recommendations for creating a plainer legal language in acts. (SR)

  7. Legislating for Terrorism: The Philippines’ Human Security Act 2007

    Directory of Open Access Journals (Sweden)

    Pauline E. Eadie

    2011-11-01

    Full Text Available In February 2007 the Philippine Senate passed the Human Security Act (HSA otherwise known as Republic Act No. 9372: An Act to Secure the State and Protect our People From Terrorism. Philippine Senate Minority Leader Aquilino Q. Pimentel Jr. was heavily involved in the final drafting of the HSA. He gave it its final name shortly before the Senate Chamber passed it into law. Previously the Act had been known by various titles including ‘An Act to Deter and Punish Acts of Terrorism and for Other Purposes’ (Senate Bill No. 2137 and ‘An Act to Define and Punish the Crime of Terrorism, the Crime of Conspiracy to Commit Terrorism, and the Crime of Proposal to Commit Terrorism, and for Other Purposes (Senate Bill No. 2187. Thus the Human Security Act exists as an instrument of counter terrorism as opposed to human security policy.

  8. On Speech Act Theory in Conversations of the Holy Bible

    Institute of Scientific and Technical Information of China (English)

    YANG Hongya

    2014-01-01

    Speech act theory is an important theory in current pragmatics, which is originated with the Oxford philosopher John Langshaw Austin. Speech act theory is started from research on daily language’s function. There are few papers using speech act theory to analyze literature works. The holy bible is a literature treasure in human history, so this paper tries to use speech act theory to analyze conversations of Bible and provide some enlightenment for readers.

  9. From ACT-ONE to Miranda, a Translation Experiment

    OpenAIRE

    Charles, Nathan; Bowman, Howard; Thompson, Simon

    1997-01-01

    It is now almost universally acknowledged that the data language ACT-ONE associated with the formal description technique LOTOS is inappropriate for the purpose of OSI formal description. In response to this the LOTOS restandardisation activity plans to replace ACT-ONE with a functional language. Thus, compatibility between ACT-ONE and the replacement data language becomes an issue. In response to this, we present an experimental investigation of backward compatibility between ACT-ONE and the...

  10. Characterizing protein crystal nucleation

    Science.gov (United States)

    Akella, Sathish V.

    We developed an experimental microfluidic based technique to measure the nucleation rates and successfully applied the technique to measure nucleation rates of lysozyme crystals. The technique involves counting the number of samples which do not have crystals as a function of time. Under the assumption that nucleation is a Poisson process, the fraction of samples with no crystals decays exponentially with the decay constant proportional to nucleation rate and volume of the sample. Since nucleation is a random and rare event, one needs to perform measurements on large number of samples to obtain good statistics. Microfluidics offers the solution of producing large number of samples at minimal material consumption. Hence, we developed a microfluidic method and measured nucleation rates of lysozyme crystals in supersaturated protein drops, each with volume of ˜ 1 nL. Classical Nucleation Theory (CNT) describes the kinetics of nucleation and predicts the functional form of nucleation rate in terms of the thermodynamic quantities involved, such as supersaturation, temperature, etc. We analyzed the measured nucleation rates in the context of CNT and obtained the activation energy and the kinetic pre-factor characterizing the nucleation process. One conclusion is that heterogeneous nucleation dominates crystallization. We report preliminary studies on selective enhancement of nucleation in one of the crystal polymorprhs of lysozyme (spherulite) using amorphous mesoporous bioactive gel-glass te{naomi06, naomi08}, CaO.P 2O5.SiO2 (known as bio-glass) with 2-10 nm pore-size diameter distribution. The pores act as heterogeneous nucleation centers and claimed to enhance the nucleation rates by molecular confinement. The measured kinetic profiles of crystal fraction of spherulites indicate that the crystallization of spherulites may be proceeding via secondary nucleation pathways.

  11. Identification and Characterization of cis-Acting Elements Residing in the Walleye Dermal Sarcoma Virus Promoter

    OpenAIRE

    Hronek, Brett W.; Meagher, Ashley; Rovnak, Joel; Quackenbush, Sandra L.

    2004-01-01

    Walleye dermal sarcoma virus (WDSV) is a complex retrovirus found associated with tumors that appear and regress on a seasonal basis. There are quantitative and qualitative differences in the amount of virus expression between developing and regressing tumors. To understand the role of host cell factors in WDSV expression, DNase I footprint analysis, electrophoretic mobility shift assays (EMSA), and reporter gene assays were employed. DNase I footprint analysis of the U3 region of the WDSV lo...

  12. Diradicals acting through diamagnetic phenylene vinylene bridges: Raman spectroscopy as a probe to characterize spin delocalization

    Energy Technology Data Exchange (ETDEWEB)

    González, Sandra Rodríguez; Nieto-Ortega, Belén; González Cano, Rafael C.; López Navarrete, Juan T., E-mail: vecianaj@icmab.es, E-mail: teodomiro@uma.es, E-mail: casado@uma.es; Casado, Juan, E-mail: vecianaj@icmab.es, E-mail: teodomiro@uma.es, E-mail: casado@uma.es [Department of Physical Chemistry, University of Málaga, Campus de Teatinos s/n, Málaga 29071 (Spain); Lloveras, Vega; Vidal-Gancedo, José; Rovira, Concepció; Veciana, Jaume, E-mail: vecianaj@icmab.es, E-mail: teodomiro@uma.es, E-mail: casado@uma.es [Department of Molecular Nanoscience and Organic Materials, Institut de Ciència de Materials de Barcelona (CSIC), Campus Universitari de Bellaterra, E-08193 Cerdanyola, Barcelona (Spain); NANOMOL group, Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Campus Universitari de Bellaterra, E-08193 Cerdanyola, Barcelona (Spain); Novoa, Juan J.; Mota, Fernando [Dpt. de Química Física and IQTCUB, Fac. Química, Univ. de Barcelona, Av. Diagonal, 647, 08028-Barcelona (Spain); Corro, Elena del; Taravillo, Mercedes; Baonza, Valentín G. [MALTA-Consolider Team, Department of Physical Chemistry, University Complutense of Madrid, Madrid 28040 (Spain)

    2014-04-28

    We present a complete Raman spectroscopic study in two structurally well-defined diradical species of different lengths incorporating oligo p-phenylene vinylene bridges between two polychlorinated triphenylmethyl radical units, a disposition that allows sizeable conjugation between the two radicals through and with the bridge. The spectroscopic data are interpreted and supported by quantum chemical calculations. We focus the attention on the Raman frequency changes, interpretable in terms of: (i) bridge length (conjugation length); (ii) bridge conformational structure; and (iii) electronic coupling between the terminal radical units with the bridge and through the bridge, which could delineate through-bond spin polarization, or spin delocalization. These items are addressed by using the “oligomer approach” in conjunction with pressure and temperature dependent Raman spectroscopic data. In summary, we have attempted to translate the well-known strategy to study the electron (charge) structure of π−conjugated molecules by Raman spectroscopy to the case of electron (spin) interactions via the spin delocalization mechanism.

  13. Discovery and information-theoretic characterization of transcription factor binding sites that act cooperatively.

    Science.gov (United States)

    Clifford, Jacob; Adami, Christoph

    2015-09-02

    Transcription factor binding to the surface of DNA regulatory regions is one of the primary causes of regulating gene expression levels. A probabilistic approach to model protein-DNA interactions at the sequence level is through position weight matrices (PWMs) that estimate the joint probability of a DNA binding site sequence by assuming positional independence within the DNA sequence. Here we construct conditional PWMs that depend on the motif signatures in the flanking DNA sequence, by conditioning known binding site loci on the presence or absence of additional binding sites in the flanking sequence of each site's locus. Pooling known sites with similar flanking sequence patterns allows for the estimation of the conditional distribution function over the binding site sequences. We apply our model to the Dorsal transcription factor binding sites active in patterning the Dorsal-Ventral axis of Drosophila development. We find that those binding sites that cooperate with nearby Twist sites on average contain about 0.5 bits of information about the presence of Twist transcription factor binding sites in the flanking sequence. We also find that Dorsal binding site detectors conditioned on flanking sequence information make better predictions about what is a Dorsal site relative to background DNA than detection without information about flanking sequence features.

  14. Discovery and information-theoretic characterization of transcription factor binding sites that act cooperatively

    CERN Document Server

    Clifford, Jacob

    2015-01-01

    Transcription factor binding to the surface of DNA regulatory regions is one of the primary causes of regulating gene expression levels. A probabilistic approach to model protein-DNA interactions at the sequence level is through Position Weight Matrices (PWMs) that estimate the joint probability of a DNA binding site sequence by assuming positional independence within the DNA sequence. Here we construct conditional PWMs that depend on the motif signatures in the flanking DNA sequence, by conditioning known binding site loci on the presence or absence of additional binding sites in the flanking sequence of each site's locus. Pooling known sites with similar flanking sequence patterns allows for the estimation of the conditional distribution function over the binding site sequences. We apply our model to the Dorsal transcription factor binding sites active in patterning the Dorsal-Ventral axis of Drosophila development. We find that those binding sites that cooperate with nearby Twist sites on average contain a...

  15. 77 FR 20011 - Fair Credit Reporting Act Disclosures

    Science.gov (United States)

    2012-04-03

    ... PROTECTION RIN 3170-AA06 Fair Credit Reporting Act Disclosures AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice regarding charges for certain disclosures under the Fair Credit Reporting Act... charges under Section 612(f) of the Fair Credit Reporting Act (``FCRA'') will increase from $11.00 to...

  16. 77 FR 74831 - Fair Credit Reporting Act Disclosures

    Science.gov (United States)

    2012-12-18

    ... PROTECTION Fair Credit Reporting Act Disclosures AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice regarding charges for certain disclosures under the Fair Credit Reporting Act. SUMMARY: The Bureau... Section 612(f) of the Fair Credit Reporting Act (FCRA) will remain unchanged at $11.50 for 2013....

  17. Three Perspectives on the 2012 ACTE National Policy Seminar

    Science.gov (United States)

    Comer, Jim; Beasley, Candice; Moody, Kimberly; Nelson, Christine

    2012-01-01

    The ACTE National Policy Seminar (NPS) is a time for Association of Career and Technical Education (ACTE) members to meet with Members of Congress or their staff, hear from high-ranking officials in various levels of government, attend educational sessions, network with fellow ACTE members and more. In this article, the authors provide their…

  18. 32 CFR 505.12 - Privacy Act enforcement actions.

    Science.gov (United States)

    2010-07-01

    ... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.12 Privacy Act enforcement actions. (a... record under false pretenses; or (iii) Maintaining a system of records without first meeting the public notice requirements of the Act. (b) Litigation Status Sheet. (1) When a complaint citing the Privacy...

  19. 17 CFR 229.801 - Securities Act industry guides.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Securities Act industry guides. 229.801 Section 229.801 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION STANDARD... AND CONSERVATION ACT OF 1975-REGULATION S-K List of Industry Guides § 229.801 Securities Act...

  20. 17 CFR 229.802 - Exchange Act industry guides.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Exchange Act industry guides. 229.802 Section 229.802 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION STANDARD... AND CONSERVATION ACT OF 1975-REGULATION S-K List of Industry Guides § 229.802 Exchange Act...

  1. 10 CFR 1304.103 - Privacy Act inquiries.

    Science.gov (United States)

    2010-01-01

    ... NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.103 Privacy Act inquiries. (a) Requests... writing may be sent to: Privacy Act Officer, U.S. Nuclear Waste Technical Review Board, 2300 Clarendon....nwtrb.gov, using the “Contact NWTRB” icon on the bottom of the Home page. The words “Privacy Act”...

  2. Acceptance and Commitment Therapy (ACT) as a Career Counselling Strategy

    Science.gov (United States)

    Hoare, P. Nancey; McIlveen, Peter; Hamilton, Nadine

    2012-01-01

    Acceptance and commitment therapy (ACT) has potential to contribute to career counselling. In this paper, the theoretical tenets of ACT and a selection of its counselling techniques are overviewed along with a descriptive case vignette. There is limited empirical research into ACT's application in career counselling. Accordingly, a research agenda…

  3. Acceptance and Commitment Therapy (ACT): An Overview for Practitioners

    Science.gov (United States)

    Bowden, Tim; Bowden, Sandra

    2012-01-01

    Acceptance and Commitment Therapy (ACT) offers school counsellors a practical and meaningful approach to helping students deal with a range of issues. This is achieved through encouraging psychological flexibility through the application of six key principles. This article describes our introduction to ACT, ACT's application to children and…

  4. DIRECTIVE SPEECH ACT IN THE MOVIE SLEEPING BEAUTY

    Directory of Open Access Journals (Sweden)

    Muhartoyo

    2013-09-01

    Full Text Available Pragmatics is one of linguistics studies that is quite attractive to learn more about. There are many aspects of pragmatics; one of them is dealing with speech acts. Speech acts consist of many categories; one of them is directive speech act. This study aims to identify the directive speech act performed in Sleeping Beauty movie. Likewise, it will find out how often the directive speech act performed and which type of directive speech act that are most frequently used in the movie. This study used qualitative method in which data collection is done by watching the movie, analyzing the body movement and the dialogues of each character, reading the script and library research. A total of 139 directive speech acts were successfully identified. The result of analysis showed that the directive speech act of ordering is the most frequently used in the movie (21,6%. The least frequently used directive speech act is inviting directive speech act (0,7%. The study also revealed the importance of directive speech act in keeping the flow of storyline of the movie. This study is expected to give some useful insights in understanding what directive speech acts is.

  5. 17 CFR 42.2 - Compliance with Bank Secrecy Act.

    Science.gov (United States)

    2010-04-01

    ... Secrecy Act and the regulations promulgated by the Department of the Treasury under that Act at 31 CFR... promulgated by the Commission and the Department of the Treasury at 31 CFR 103.123, which require that a customer identification program be adopted as part of the firm's Bank Secrecy Act compliance program....

  6. 37 CFR 251.23 - FOIA and Privacy Act.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false FOIA and Privacy Act. 251.23 Section 251.23 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT... Access to and Inspection of Records § 251.23 FOIA and Privacy Act. Freedom of Information Act and...

  7. 43 CFR 7.4 - Prohibited acts and criminal penalties.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Prohibited acts and criminal penalties. 7... ARCHAEOLOGICAL RESOURCES Uniform Regulations § 7.4 Prohibited acts and criminal penalties. (a) Under section 6(a... effect under any other provision of Federal law. (c) Under section (d) of the Act, any person...

  8. 48 CFR 52.224-2 - Privacy Act.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Privacy Act. 52.224-2... AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 52.224-2 Privacy... agency function: Privacy Act (APR 1984) (a) The Contractor agrees to— (1) Comply with the Privacy Act...

  9. 48 CFR 352.224-70 - Privacy Act.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Privacy Act. 352.224-70... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 352.224-70 Privacy Act. As prescribed in 324.103(b)(2), the Contracting Officer shall insert the following clause: Privacy Act...

  10. 77 FR 34233 - Telephone Consumer Protection Act of 1991

    Science.gov (United States)

    2012-06-11

    ... Implementation Act (``DNCIA'') in a way that reduces industry confusion about telemarketers' obligations and does... COMMISSION 47 CFR Part 64 Telephone Consumer Protection Act of 1991 AGENCY: Federal Communications Commission... Insurance Portability and Accountability Act of 1996. Taken together, today's actions offer...

  11. 16 CFR 1031.3 - Consumer Product Safety Act amendments.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Consumer Product Safety Act amendments. 1031.3 Section 1031.3 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION... Consumer Product Safety Act amendments. The Consumer Product Safety Act, as amended, contains...

  12. Administrative changes (Consequential Provisions) Act 1976, No. 91

    International Nuclear Information System (INIS)

    This Act which amends a series of Acts from the viewpoint of administrative changes also amends the Atomic Energy Act 1953 by laying down that the Territories of Papua and New Guinea are henceforth to be omitted from the list of Territories for which the Atomic Energy Commission must obtain approval from the competent Minister before exercising its powers. (NEA)

  13. 29 CFR 8.19 - Equal Access to Justice Act.

    Science.gov (United States)

    2010-07-01

    ... SERVICE CONTRACTS General Procedural Matters § 8.19 Equal Access to Justice Act. Proceedings under the... 29 Labor 1 2010-07-01 2010-07-01 true Equal Access to Justice Act. 8.19 Section 8.19 Labor Office... Access to Justice Act (Pub. L. 96-481). Accordingly, in any proceeding conducted pursuant to...

  14. 78 FR 20912 - Clean Water Act: Availability of List Decisions

    Science.gov (United States)

    2013-04-08

    ... AGENCY Clean Water Act: Availability of List Decisions AGENCY: Environmental Protection Agency (EPA). ACTION: Notice and initial request for public input. SUMMARY: The Clean Water Act requires that States... Richardson at (215) 814-5675. SUPPLEMENTARY INFORMATION: Section 303(d) of the Clean Water Act requires...

  15. 77 FR 16548 - Clean Air Act Advisory Committee

    Science.gov (United States)

    2012-03-21

    ... AGENCY Clean Air Act Advisory Committee AGENCY: Environmental Protection Agency (EPA). ACTION: Request for Nominations to the Clean Air Act Advisory Committee. SUMMARY: The U.S. Environmental Protection... appointment to its Clean Air Act Advisory Committee (CAAAC). Applications are due by May 1, 2012 and...

  16. 49 CFR 1105.9 - Coastal Zone Management Act requirements.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Coastal Zone Management Act requirements. 1105.9... ENVIRONMENTAL LAWS § 1105.9 Coastal Zone Management Act requirements. (a) If the proposed action affects land or water uses within a State coastal zone designated pursuant to the Coastal Zone Management Act (16...

  17. Automated Discovery of Speech Act Categories in Educational Games

    Science.gov (United States)

    Rus, Vasile; Moldovan, Cristian; Niraula, Nobal; Graesser, Arthur C.

    2012-01-01

    In this paper we address the important task of automated discovery of speech act categories in dialogue-based, multi-party educational games. Speech acts are important in dialogue-based educational systems because they help infer the student speaker's intentions (the task of speech act classification) which in turn is crucial to providing adequate…

  18. 76 FR 77472 - Privacy Act of 1974, as Amended

    Science.gov (United States)

    2011-12-13

    ... PROTECTION Privacy Act of 1974, as Amended AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice of Proposed Privacy Act System of Records. SUMMARY: In accordance with the Privacy Act of 1974, as amended, the Bureau of Consumer Financial Protection, hereinto referred to as the Consumer Financial...

  19. 76 FR 45765 - Privacy Act of 1974, as Amended

    Science.gov (United States)

    2011-08-01

    ... PROTECTION Privacy Act of 1974, as Amended AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice of Proposed Privacy Act System of Records. SUMMARY: In accordance with the Privacy Act of 1974, as amended, the Bureau of Consumer Financial Protection, hereinto referred to as the Consumer Financial...

  20. 77 FR 35359 - Privacy Act of 1974, as Amended

    Science.gov (United States)

    2012-06-13

    ... PROTECTION Privacy Act of 1974, as Amended AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice of proposed Privacy Act System of Records. SUMMARY: In accordance with the Privacy Act of 1974, as amended, the Bureau of Consumer Financial Protection, hereinto referred to as the Consumer Financial...

  1. 76 FR 45763 - Privacy Act of 1974, as Amended

    Science.gov (United States)

    2011-08-01

    ... PROTECTION Privacy Act of 1974, as Amended AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice of Proposed Privacy Act System of Records. SUMMARY: In accordance with the Privacy Act of 1974, as amended, the Bureau of Consumer Financial Protection, hereinto referred to as the Consumer Financial...

  2. 78 FR 47306 - Privacy Act of 1974, as Amended

    Science.gov (United States)

    2013-08-05

    ... PROTECTION Privacy Act of 1974, as Amended AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice of a Revised Privacy Act System of Records. SUMMARY: In accordance with the Privacy Act of 1974, as amended, the Bureau of Consumer Financial Protection, hereinto referred to as the Consumer...

  3. 31 CFR 306.76 - Fiduciaries acting as a unit.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Fiduciaries acting as a unit. 306.76.... SECURITIES Assignments by or in Behalf of Trustees and Similar Fiduciaries § 306.76 Fiduciaries acting as a... to act as a unit for any public or private trust estate may be assigned for any...

  4. 76 FR 45761 - Privacy Act of 1974, as Amended

    Science.gov (United States)

    2011-08-01

    ... PROTECTION Privacy Act of 1974, as Amended AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice of Proposed Privacy Act System of Records. SUMMARY: In accordance with the Privacy Act of 1974, as amended, the Bureau of Consumer Financial Protection, hereinto referred to as the Consumer Financial...

  5. 78 FR 69834 - Privacy Act of 1974, as Amended

    Science.gov (United States)

    2013-11-21

    ... PROTECTION Privacy Act of 1974, as Amended AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice of Proposed Privacy Act System of Records. SUMMARY: In accordance with the Privacy Act of 1974, as amended, the Bureau of Consumer Financial Protection, hereinto referred to as the Consumer Financial...

  6. 78 FR 34991 - Privacy Act of 1974, as Amended

    Science.gov (United States)

    2013-06-11

    ... PROTECTION Privacy Act of 1974, as Amended AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice of Proposed Privacy Act System of Records. SUMMARY: In accordance with the Privacy Act of 1974, as amended, the Bureau of Consumer Financial Protection, hereinto referred to as the Consumer Financial...

  7. 77 FR 56623 - Privacy Act of 1974, as Amended

    Science.gov (United States)

    2012-09-13

    ... PROTECTION Privacy Act of 1974, as Amended AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice of Proposed Privacy Act System of Records. SUMMARY: In accordance with the Privacy Act of 1974, as amended, the Bureau of Consumer Financial Protection, herein referred to as the Consumer Financial...

  8. Energy transport corridors: the potential role of Federal lands in states identified by the Energy Policy Act of 2005, section 368(b).

    Energy Technology Data Exchange (ETDEWEB)

    Krummel, J.; Hlohowskyj, I.; Kuiper, J.; Kolpa, R.; Moore, R.; May, J.; VanKuiken, J.C.; Kavicky, J.A.; McLamore, M.R.; Shamsuddin, S. (Decision and Information Sciences); ( EVS)

    2011-09-01

    On August 8, 2005, the President signed the Energy Policy Act of 2005 (EPAct) into law. In Subtitle F of EPAct, Congress set forth various provisions that would change the way certain federal agencies (Agencies) coordinate to authorize the use of land for a variety of energy-related purposes. As part of Subtitle F of EPAct, Section 368 addresses the issue of energy transportation corridors on federal land for oil, gas, and hydrogen pipelines, as well as electricity transmission and distribution facilities. Because of the critical importance of improving the nation's electrical transmission grid, Congress recognized that electricity transmission issues should receive added attention when the Agencies address corridor location and analysis issues. In Section 368, Congress specifically directed the Agencies to consider the need for upgraded and new facilities to deliver electricity: In carrying out [Section 368], the Secretaries shall take into account the need for upgraded and new electricity transmission and distribution facilities to (1) improve reliability; (2) relieve congestion; and (3) enhance capability of the national grid to deliver electricity. Section 368 does not require the Agencies to consider or approve specific projects, applications for rights-of-way (ROWs), or other permits within designated energy corridors. Importantly, Section 368 does not direct, license, or otherwise permit any on-the-ground activity of any sort. If an applicant is interested in obtaining an authorization to develop a project within any corridor designated under Section 368, the applicant would have to apply for a ROW authorization and applicable permits. The Agencies would consider each application by applying appropriate project-specific reviews under requirements of laws and related regulations, including, but not limited to, the National Environmental Policy Act (NEPA), the Clean Water Act, the Clean Air Act, Section 7 of the Endangered Species Act (ESA), and Section

  9. Handbook of technology law. General funamentals, environment law, genetic engineering act, energy act, telecommunication act and media act, patent act, computer act. 2. ed.; Handbuch des Technikrechts. Allgemeine Grundlagen Umweltrecht, Gentechnikrecht, Energierecht, Telekommunikations- und Medienrecht, Patentrecht, Computerrecht

    Energy Technology Data Exchange (ETDEWEB)

    Schulte, Martin; Schroeder, Rainer (eds.) [Technische Univ. Dresden (Germany). Juristische Fakultaet

    2011-07-01

    On the boundaries between technology sciences, jurisprudence, social sciences and economic science the technology law proves as a cross-sectional area par excellence. The bases of the technology law are presented: individual, particularly important scopes of the technology law (appliance safety regulations, technology law and environment law, genetic engineering act, energy right, telecommunications law and media law, patent law, computer law, data security, legally binding telecooperation) are analyzed in detail. The manual contacts all lawyers who want to provide a first in-depth insight of this new field of law. [German] Im Grenzbereich von Technik-, Rechts-, Sozial- und Wirtschaftswissenschaften erweist sich das Technikrecht als Querschnittsmaterie par excellence. Die Grundlagen des Technikrechts werden dargestellt; einzelne, besonders wichtige Bereiche des Technikrechts (Geraetesicherheitsrecht, Technik und Umweltrecht, Gentechnikrecht, Energierecht, Telekommunikations- und Medienrecht, Patentrecht, Computerrecht, Datensicherheit, Rechtsverbindliche Telekooperation) werden eingehend analysiert. Das Handbuch wendet sich an alle in Wissenschaft und Praxis mit dem Technikrecht befassten Juristen, die sich einen ersten vertieften Einblick in dieses neue Rechtsgebiet verschaffen wollen. (orig.)

  10. 75 FR 52300 - Merchant Marine Act and Magnuson-Stevens Fishery Conservation and Management Act Provisions...

    Science.gov (United States)

    2010-08-25

    ... National Oceanic and Atmospheric Administration 50 CFR Part 253 RIN 0648-AY16 Merchant Marine Act and... Individual Fishing Quota Lending Program Regulations; Correction AGENCY: National Marine Fisheries Service... at 75 FR 24549. Comments must be submitted in writing on or before September 8, 2010. ADDRESSES:...

  11. "Speech Act" Fra Teoria e Prassi Didattica. (The Speech Act between Theory and Pedagogical Practice).

    Science.gov (United States)

    Minardi, Giovanni

    1982-01-01

    The author traces the development of speech act theory from Wittgenstein and Austin through Searle to Grice and shows how their work led to the notional functional approach to language teaching, which is based on the learner and his/her communicative needs. (CFM)

  12. Updating the ACT College Readiness Benchmarks. ACT Research Report Series 2013 (6)

    Science.gov (United States)

    Allen, Jeff

    2013-01-01

    The ACT College Readiness Benchmarks are the ACT® College Readiness Assessment scores associated with a 50% chance of earning a B or higher grade in typical first-year credit-bearing college courses. The Benchmarks also correspond to an approximate 75% chance of earning a C or higher grade in these courses. There are four Benchmarks, corresponding…

  13. Immaturités en acte

    Directory of Open Access Journals (Sweden)

    Dominique Ottavi

    2007-01-01

    Full Text Available Un certain nombre de films noirs marqués par la psychanalyse manifestent ce que l’on peut appeler l’« immaturité en acte », c’est-à-dire, relatent des crimes commis par des personnages qui combinent une grande assurance et une fragilité, un inachèvement, internes. Cette fragilité peut être portée au compte de l’immaturité dans les cas où elle provient d’un rapport troublé à la parenté et à la succession des générations. L’intérêt de cette thématique dépasse le repérage d’un thème de fiction, ...

  14. Constitutionality of the Atomic Energy Act

    International Nuclear Information System (INIS)

    Roma locuta, causa finita. The Federal Constitutional Court declared in its decree of 8 August 1978 the peaceful uses of nuclear energy (Paragraph 7 sub-section 1 and 2 Atomic Energy Act) in NPPs of the so-called fast breeder type as constitutional for the time being. The excellent simplicity of the explanations, namely about the anavoidability and social adequancy of the so-called residual risk in a highly technical society and about the determining influence of practical ratio as a measure for the estimation of the residual risk which must be born by all citizens, creates a good clarification on the level of constitutional law. However, it remains, to be seen whether the decree can give the administrative courts any orientation help in the future and whether it will lead to an improved legal protection of all participants and a more effective handling of administrative processes. (orig.)

  15. World AIDS Day: a time to act.

    Science.gov (United States)

    1994-05-01

    The AIDS Control and Prevention Project (AIDSCAP) used World AIDS Day 1993 and its theme "A Time to Act" as an opportunity to focus attention on the urgency of the struggle against AIDS. Some of the events AIDSCAP promoted included the release of hundreds of balloons inscribed with the message "Think: AIDS is Still Here" in Haiti, where a major radio station also devoted all of the day's advertising time to HIV/AIDS prevention messages; the distribution of 500,000 condoms as inserts in a major Brazilian newspaper; and a 15-km walk in Ethiopia undertaken by thousands of people to promote AIDS prevention. While such events are not expected to have a measurable impact on the epidemic, they could instigate the long-term efforts to create a social environment conducive to HIV prevention through individual behavior change. The theme chosen for the 1994 World AIDS Day is "AIDS and the Family." PMID:12345905

  16. Corrado Pettenati acting head of ETT

    CERN Multimedia

    2004-01-01

    Following the departure of Juan Antonio Rubio, Corrado Pettenati has been appointed as the acting head of the ETT unit with effect from 1 August. He joined CERN in 1995 as head librarian, reorganizing and modernizing the library before becoming deputy leader of ETT from June 2000 to April 2004. Previously, he worked at the European University Institute in Florence from 1976, developing automated library systems and becoming head of the computer centre in 1985. He has also been a software analyst and a telecommunications specialist. In 2003 he was appointed as member of the steering committee of the Cellule de Coordination Documentaire Nationale pour les Mathématiques de Grenoble, and in 2004 became a member of the EULER - European Libraries and Electronic Resources in Mathematical Sciences - Scientific Advisory Board, based in Germany. He was born in 1946 and graduated with a degree in Electrical Engineering from the Polytechnic in Milan in 1969.

  17. Standardized loads acting in knee implants.

    Science.gov (United States)

    Bergmann, Georg; Bender, Alwina; Graichen, Friedmar; Dymke, Jörn; Rohlmann, Antonius; Trepczynski, Adam; Heller, Markus O; Kutzner, Ines

    2014-01-01

    The loads acting in knee joints must be known for improving joint replacement, surgical procedures, physiotherapy, biomechanical computer simulations, and to advise patients with osteoarthritis or fractures about what activities to avoid. Such data would also allow verification of test standards for knee implants. This work analyzes data from 8 subjects with instrumented knee implants, which allowed measuring the contact forces and moments acting in the joint. The implants were powered inductively and the loads transmitted at radio frequency. The time courses of forces and moments during walking, stair climbing, and 6 more activities were averaged for subjects with I) average body weight and average load levels and II) high body weight and high load levels. During all investigated activities except jogging, the high force levels reached 3,372-4,218N. During slow jogging, they were up to 5,165N. The peak torque around the implant stem during walking was 10.5 Nm, which was higher than during all other activities including jogging. The transverse forces and the moments varied greatly between the subjects, especially during non-cyclic activities. The high load levels measured were mostly above those defined in the wear test ISO 14243. The loads defined in the ISO test standard should be adapted to the levels reported here. The new data will allow realistic investigations and improvements of joint replacement, surgical procedures for tendon repair, treatment of fractures, and others. Computer models of the load conditions in the lower extremities will become more realistic if the new data is used as a gold standard. However, due to the extreme individual variations of some load components, even the reported average load profiles can most likely not explain every failure of an implant or a surgical procedure.

  18. Standardized loads acting in knee implants.

    Directory of Open Access Journals (Sweden)

    Georg Bergmann

    Full Text Available The loads acting in knee joints must be known for improving joint replacement, surgical procedures, physiotherapy, biomechanical computer simulations, and to advise patients with osteoarthritis or fractures about what activities to avoid. Such data would also allow verification of test standards for knee implants. This work analyzes data from 8 subjects with instrumented knee implants, which allowed measuring the contact forces and moments acting in the joint. The implants were powered inductively and the loads transmitted at radio frequency. The time courses of forces and moments during walking, stair climbing, and 6 more activities were averaged for subjects with I average body weight and average load levels and II high body weight and high load levels. During all investigated activities except jogging, the high force levels reached 3,372-4,218N. During slow jogging, they were up to 5,165N. The peak torque around the implant stem during walking was 10.5 Nm, which was higher than during all other activities including jogging. The transverse forces and the moments varied greatly between the subjects, especially during non-cyclic activities. The high load levels measured were mostly above those defined in the wear test ISO 14243. The loads defined in the ISO test standard should be adapted to the levels reported here. The new data will allow realistic investigations and improvements of joint replacement, surgical procedures for tendon repair, treatment of fractures, and others. Computer models of the load conditions in the lower extremities will become more realistic if the new data is used as a gold standard. However, due to the extreme individual variations of some load components, even the reported average load profiles can most likely not explain every failure of an implant or a surgical procedure.

  19. Mechanism and regulation of the Two-component FMN-dependent monooxygenase ActVA-ActVB from Streptomyces coelicolor.

    OpenAIRE

    Valton, Julien; Mathevon, Carole; Fontecave, Marc; Nivière, Vincent; Ballou, David P.

    2008-01-01

    International audience The ActVA-ActVB system from Streptomyces coelicolor is a two-component flavin-dependent monooxygenase involved in the antibiotic actinorhodin biosynthesis. ActVB is a NADH:flavin oxidoreductase that provides a reduced FMN to ActVA, the monooxygenase that catalyzes the hydroxylation of dihydrokalafungin, the precursor of actinorhodin. In this work, using stopped-flow spectrophotometry, we investigated the mechanism of hydroxylation of dihydrokalafungin catalyzed by Ac...

  20. 76 FR 72973 - Notice of Lodging of Consent Decree Under the Clean Water Act and Safe Drinking Water Act

    Science.gov (United States)

    2011-11-28

    ... of Lodging of Consent Decree Under the Clean Water Act and Safe Drinking Water Act Notice is hereby.... 1251-387; the Safe Drinking Water Act, 42 U.S.C. 300f-300j-26; the West Virginia Water Pollution... and drinking water treatment system (collectively, the ``Facilities''), and to improve staffing at...