WorldWideScience

Sample records for acoustic nmr

  1. Time-Lapse Acoustic, Transport, and NMR Measurements to Monitor Induced Microstructural Changes of Carbonate Rocks During Injection of CO2-Rich Water

    Science.gov (United States)

    Grombacher, D.; Vanorio, T.; Ebert, Y.

    2011-12-01

    Geophysical monitoring during CO2 injection is necessary to ensure that 1) injected CO2 fills the reservoir as predicted, and that 2) injected CO2 does not migrate towards regions where it may escape. Injection of CO2 results in an altered equilibrium between the pore fluid and the host rock causing chemo-mechanical processes to occur which may impact rock frame properties. In order to improve monitoring techniques, further characterization of injection-induced microstructural changes due to chemo-mechanical processes is needed. We attempt to answer the following questions: How does injection alter the pore network, and how do injection-induced microstructural changes impact seismic properties? An experiment consisting of a suite of six concurrent and independent time-lapse measurements including permeability, porosity, acoustic, nuclear magnetic resonance (NMR) T2 relaxation, and scanning electron microscopy (SEM) and CT-scan images were conducted on two types of carbonate rocks (micritic limestones, and chalky, micritic carbonates). Measurements were taken as a function of the total injected volume of CO2-rich water (which mimics CO2 injection). Injections took place both under bench top conditions and under conditions of constant confining and pore pressures of 15MPa and 12MPa, respectively. Each measurement type is independent and sensitive to different pore properties, allowing us to determine how the microstructure is altered by considering the data from all measurement types simultaneously. Additionally, time-lapse measurements allow us to quantify induced pore structure changes. With increased injection of CO2-rich water, micritic limestones exhibit increased sensitivity of velocity to confining pressure, large permeability increases (~200%), and much variation in their T2 distribution. We hypothesize that injection alters the pore network by increasing pore connectivity and promoting the formation of more elongated pores. In contrast, chalkly, micritic

  2. Architectural acoustics

    National Research Council Canada - National Science Library

    Long, Marshall

    2014-01-01

    .... Beginning with a brief history, it reviews the fundamentals of acoustics, human perception and reaction to sound, acoustic noise measurements, noise metrics, and environmental noise characterization...

  3. Virtual Acoustics

    Science.gov (United States)

    Lokki, Tapio; Savioja, Lauri

    The term virtual acoustics is often applied when sound signal is processed to contain features of a simulated acoustical space and sound is spatially reproduced either with binaural or with multichannel techniques. Therefore, virtual acoustics consists of spatial sound reproduction and room acoustics modeling.

  4. Communication Acoustics

    DEFF Research Database (Denmark)

    Blauert, Jens

    Communication Acoustics deals with the fundamentals of those areas of acoustics which are related to modern communication technologies. Due to the advent of digital signal processing and recording in acoustics, these areas have enjoyed an enormous upswing during the last 4 decades. The book chapt......: acoustics, cognitive science, speech science, and communication technology.......Communication Acoustics deals with the fundamentals of those areas of acoustics which are related to modern communication technologies. Due to the advent of digital signal processing and recording in acoustics, these areas have enjoyed an enormous upswing during the last 4 decades. The book...... the book a source of valuable information for those who want to improve or refresh their knowledge in the field of communication acoustics - and to work their way deeper into it. Due to its interdisciplinary character Communication Acoustics is bound to attract readers from many different areas, such as...

  5. Communication Acoustics

    DEFF Research Database (Denmark)

    Blauert, Jens

    Communication Acoustics deals with the fundamentals of those areas of acoustics which are related to modern communication technologies. Due to the advent of digital signal processing and recording in acoustics, these areas have enjoyed an enormous upswing during the last 4 decades. The book...... the book a source of valuable information for those who want to improve or refresh their knowledge in the field of communication acoustics - and to work their way deeper into it. Due to its interdisciplinary character Communication Acoustics is bound to attract readers from many different areas, such as......: acoustics, cognitive science, speech science, and communication technology....

  6. Communication Acoustics

    DEFF Research Database (Denmark)

    Blauert, Jens

    the book a source of valuable information for those who want to improve or refresh their knowledge in the field of communication acoustics - and to work their way deeper into it. Due to its interdisciplinary character Communication Acoustics is bound to attract readers from many different areas, such as......Communication Acoustics deals with the fundamentals of those areas of acoustics which are related to modern communication technologies. Due to the advent of digital signal processing and recording in acoustics, these areas have enjoyed an enormous upswing during the last 4 decades. The book......: acoustics, cognitive science, speech science, and communication technology....

  7. Communication Acoustics

    DEFF Research Database (Denmark)

    Blauert, Jens

    Communication Acoustics deals with the fundamentals of those areas of acoustics which are related to modern communication technologies. Due to the advent of digital signal processing and recording in acoustics, these areas have enjoyed an enormous upswing during the last 4 decades. The book......: acoustics, cognitive science, speech science, and communication technology....... the book a source of valuable information for those who want to improve or refresh their knowledge in the field of communication acoustics - and to work their way deeper into it. Due to its interdisciplinary character Communication Acoustics is bound to attract readers from many different areas, such as...

  8. Acoustic Neuroma

    Science.gov (United States)

    An acoustic neuroma is a benign tumor that develops on the nerve that connects the ear to the brain. ... can press against the brain, becoming life-threatening. Acoustic neuroma can be difficult to diagnose, because the ...

  9. NMR of lignins

    Science.gov (United States)

    John Ralph; Larry L. Landucci

    2010-01-01

    This chapter will consider the basic aspects and findings of several forms of NMR spectroscopy, including separate discussions of proton, carbon, heteronuclear, and multidimensional NMR. Enhanced focus will be on 13C NMR, because of its qualitative and quantitative importance, followed by NMR’s contributions to our understanding of lignin...

  10. RADIATION ACOUSTICS

    OpenAIRE

    Lyamshev, L.

    1990-01-01

    Radiation acoustics is a new branch of acoustics. Its' fundamentals are lying in the research of acoustical effects due to the interaction of a radiation with matter. The sound excitation in liquids and solids by modulated or pulsed particle beams (electron, proton, ion beams, γ-radiation and single high-energy elementary particles) and some practical applications are discussed.

  11. Acoustical Imaging

    CERN Document Server

    Litniewski, Jerzy; Kujawska, Tamara; 31st International Symposium on Acoustical Imaging

    2012-01-01

    The International Symposium on Acoustical Imaging is a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. This interdisciplinary Symposium has been taking place continuously since 1968. In the course of the years the proceedings volumes in the Acoustical Imaging Series have become a reference for cutting-edge research in the field. In 2011 the 31st International Symposium on Acoustical Imaging was held in Warsaw, Poland, April 10-13. Offering both a broad perspective on the state-of-the-art as well as  in-depth research contributions by the specialists in the field, this Volume 31 in the Series contains an excellent collection of papers in six major categories: Biological and Medical Imaging Physics and Mathematics of Acoustical Imaging Acoustic Microscopy Transducers and Arrays Nondestructive Evaluation and Industrial Applications Underwater Imaging

  12. Acoustic textiles

    CERN Document Server

    Nayak, Rajkishore

    2016-01-01

    This book highlights the manufacturing and applications of acoustic textiles in various industries. It also includes examples from different industries in which acoustic textiles can be used to absorb noise and help reduce the impact of noise at the workplace. Given the importance of noise reduction in the working environment in several industries, the book offers a valuable guide for companies, educators and researchers involved with acoustic materials.

  13. Musical Acoustics

    Science.gov (United States)

    Gough, Colin

    This chapter provides an introduction to the physical and psycho-acoustic principles underlying the production and perception of the sounds of musical instruments. The first section introduces generic aspects of musical acoustics and the perception of musical sounds, followed by separate sections on string, wind and percussion instruments.

  14. Communication Acoustics

    DEFF Research Database (Denmark)

    Blauert, Jens

    Communication Acoustics deals with the fundamentals of those areas of acoustics which are related to modern communication technologies. Due to the advent of digital signal processing and recording in acoustics, these areas have enjoyed an enormous upswing during the last 4 decades. The book...... chapters represent review articles covering the most relevant areas of the field. They are written with the goal of providing students with comprehensive introductions. Further they offer a supply of numerous references to the relevant literature. Besides its usefulness as a textbook, this will make...... the book a source of valuable information for those who want to improve or refresh their knowledge in the field of communication acoustics - and to work their way deeper into it. Due to its interdisciplinary character Communication Acoustics is bound to attract readers from many different areas, such as...

  15. NMR logging apparatus

    Science.gov (United States)

    Walsh, David O; Turner, Peter

    2014-05-27

    Technologies including NMR logging apparatus and methods are disclosed. Example NMR logging apparatus may include surface instrumentation and one or more downhole probes configured to fit within an earth borehole. The surface instrumentation may comprise a power amplifier, which may be coupled to the downhole probes via one or more transmission lines, and a controller configured to cause the power amplifier to generate a NMR activating pulse or sequence of pulses. Impedance matching means may be configured to match an output impedance of the power amplifier through a transmission line to a load impedance of a downhole probe. Methods may include deploying the various elements of disclosed NMR logging apparatus and using the apparatus to perform NMR measurements.

  16. Acoustics Research

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Fisheries acoustics data are collected from more than 200 sea-days each year aboard the FRV DELAWARE II and FRV ALBATROSS IV (decommissioned) and the FSV Henry B....

  17. Room Acoustics

    Science.gov (United States)

    Kuttruff, Heinrich; Mommertz, Eckard

    The traditional task of room acoustics is to create or formulate conditions which ensure the best possible propagation of sound in a room from a sound source to a listener. Thus, objects of room acoustics are in particular assembly halls of all kinds, such as auditoria and lecture halls, conference rooms, theaters, concert halls or churches. Already at this point, it has to be pointed out that these conditions essentially depend on the question if speech or music should be transmitted; in the first case, the criterion for transmission quality is good speech intelligibility, in the other case, however, the success of room-acoustical efforts depends on other factors that cannot be quantified that easily, not least it also depends on the hearing habits of the listeners. In any case, absolutely "good acoustics" of a room do not exist.

  18. Acoustical Imaging

    CERN Document Server

    Akiyama, Iwaki

    2009-01-01

    The 29th International Symposium on Acoustical Imaging was held in Shonan Village, Kanagawa, Japan, April 15-18, 2007. This interdisciplinary Symposium has been taking place every two years since 1968 and forms a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. In the course of the years the volumes in the Acoustical Imaging Series have developed and become well-known and appreciated reference works. Offering both a broad perspective on the state-of-the-art in the field as well as an in-depth look at its leading edge research, this Volume 29 in the Series contains again an excellent collection of seventy papers presented in nine major categories: Strain Imaging Biological and Medical Applications Acoustic Microscopy Non-Destructive Evaluation and Industrial Applications Components and Systems Geophysics and Underwater Imaging Physics and Mathematics Medical Image Analysis FDTD method and Other Numerical Simulations Audience Researcher...

  19. Acoustic Neuroma

    Science.gov (United States)

    ... in June 1969 at Karolinska Hospital in Stockholm, Sweden. Since then, more than 10,000 acoustic neuroma ... of neurosurgeons, radiation oncologists, medical physicists and a nursing staff. Specialists in neuroimaging join the team when ...

  20. Battlefield acoustics

    CERN Document Server

    Damarla, Thyagaraju

    2015-01-01

    This book presents all aspects of situational awareness in a battlefield using acoustic signals. It starts by presenting the science behind understanding and interpretation of sound signals. The book then goes on to provide various signal processing techniques used in acoustics to find the direction of sound source, localize gunfire, track vehicles, and detect people. The necessary mathematical background and various classification and fusion techniques are presented. The book contains majority of the things one would need to process acoustic signals for all aspects of situational awareness in one location. The book also presents array theory, which is pivotal in finding the direction of arrival of acoustic signals. In addition, the book presents techniques to fuse the information from multiple homogeneous/heterogeneous sensors for better detection. MATLAB code is provided for majority of the real application, which is a valuable resource in not only understanding the theory but readers, can also use the code...

  1. Acoustic biosensors.

    Science.gov (United States)

    Fogel, Ronen; Limson, Janice; Seshia, Ashwin A

    2016-06-30

    Resonant and acoustic wave devices have been researched for several decades for application in the gravimetric sensing of a variety of biological and chemical analytes. These devices operate by coupling the measurand (e.g. analyte adsorption) as a modulation in the physical properties of the acoustic wave (e.g. resonant frequency, acoustic velocity, dissipation) that can then be correlated with the amount of adsorbed analyte. These devices can also be miniaturized with advantages in terms of cost, size and scalability, as well as potential additional features including integration with microfluidics and electronics, scaled sensitivities associated with smaller dimensions and higher operational frequencies, the ability to multiplex detection across arrays of hundreds of devices embedded in a single chip, increased throughput and the ability to interrogate a wider range of modes including within the same device. Additionally, device fabrication is often compatible with semiconductor volume batch manufacturing techniques enabling cost scalability and a high degree of precision and reproducibility in the manufacturing process. Integration with microfluidics handling also enables suitable sample pre-processing/separation/purification/amplification steps that could improve selectivity and the overall signal-to-noise ratio. Three device types are reviewed here: (i) bulk acoustic wave sensors, (ii) surface acoustic wave sensors, and (iii) micro/nano-electromechanical system (MEMS/NEMS) sensors. © 2016 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

  2. Acoustic microscopy

    CERN Document Server

    Briggs, Andrew

    2010-01-01

    For many years 'Acoustic Microscopy' has been the definitive book on the subject. A key development since it was first published has been the development of ultrasonic force microscopy. This edition has a major new chapter on this technique and its applications.

  3. NMR, water and plants

    NARCIS (Netherlands)

    As, van H.

    1982-01-01

    This Thesis describes the application of a non-destructive pulsed proton NMR method mainly to measure water transport in the xylem vessels of plant stems and in some model systems. The results are equally well applicable to liquid flow in other biological objects than plants, e.g. flow of blood and

  4. Single-sided NMR

    CERN Document Server

    Casanova, Federico; Blümich, Bernhard

    2011-01-01

    Single-Sided NMR describes the design of the first functioning single-sided tomograph, the related measurement methods, and a number of applications. One of the key advantages to this method is the speed at which the images are obtained.

  5. NMR for chemists and biologists

    CERN Document Server

    Carbajo, Rodrigo J

    2013-01-01

    This book offers a concise introduction to the field of nuclear magnetic resonance or NMR. It presents the basic foundations of NMR in a non-mathematical way and provides an overview of both recent and important biological applications of NMR.

  6. Acoustic Territoriality

    DEFF Research Database (Denmark)

    Kreutzfeldt, Jacob

    2011-01-01

    Under the heading of "Gang i København" a number of initiatives was presented by the Lord Mayer and the Technical and Environmental Mayer of Copenhagen in May 2006. The aim of the initiative, which roughly translates to Lively Copenhagen, was both to make Copenhagen a livelier city in terms of ci...... this article outline a few approaches to a theory of acoustic territoriality....

  7. Acoustic chaos

    Energy Technology Data Exchange (ETDEWEB)

    Lauterborn, W.; Parlitz, U. [Drittes Physikalisches Institut, Universitaet Goettingen, D-37073 Goettingen (Germany); Holzfuss, J.; Billo, A. [Institut fuer Angewandte Physik, Technische Hochschule Darmstadt, D-64289 Darmstadt (Germany); Akhatov, I. [Department of Continuous Media Mechanics, Bashkir State University, Ufa 450074 (Russia)

    1996-06-01

    Acoustic cavitation, a complex, spatio-temporal dynamical system, is investigated with respect to its chaotic properties. The sound output, the {open_quote}{open_quote}noise{close_quote}{close_quote}, is subjected to time series analysis. The spatial dynamics of the bubble filaments is captured by high speed holographic cinematography and subsequent digital picture processing from the holograms. Theoretical models are put forward for describing the pattern formation. {copyright} {ital 1996 American Institute of Physics.}

  8. NMR Studies of Peroxidases.

    Science.gov (United States)

    Veitch, Nigel Charles

    Available from UMI in association with The British Library. Requires signed TDF. Peroxidases are a haem-containing group of enzymes with a wide diversity of function within biological systems. While a common characteristic is the ability to catalyse the conversion of hydrogen peroxide to water, it is the accompanying processes of hormone synthesis and degradation which have generated such a high level of interest. However, information at the molecular level is limited to a single well-resolved crystal structure, that of yeast cytochrome c peroxidase. This thesis presents a strategy for the investigation of peroxidase structure and function based on proton nuclear magnetic resonance spectroscopy, a technique which has the ability to address aspects of both protein structure and protein dynamics in solution. The application of one- and two-dimensional NMR techniques has been developed in the context of plant peroxidases, notably the isoenzyme HRP-C derived from the horseradish root. Characterisation of the proton NMR spectra of HRP -C in resting and ligated states provided new information enabling the structure of the binding site for aromatic donor molecules, such as indole-3-propionic, ferulic and benzhydroxamic acids, to be resolved. In order to overcome difficulties encountered with a protein of the complexity of peroxidase, additional information was obtained from chemical shift parameters and the use of peroxidase variants produced by site-directed mutagenesis. A comparative study using NMR spectroscopy was undertaken for wild-type recombinant HRP-C expressed in Escherichia coli, and two protein variants with substitutions made to residues located on the distal side of the haem pocket, Phe41 to Val and Arg38 to Lys. NMR analyses of a plant peroxidase from barley grains and the fungal peroxidase from Coprinus cinereus were also successful using methods conceived with HRP-C. Examination of three specifically constructed recombinant protein variants of C. cinereus

  9. Acoustic Neuroma Association

    Science.gov (United States)

    ... EVENTS DONATE NEWS Home Learn Back Learn about acoustic neuroma AN Facts What is acoustic neuroma? Diagnosing ... Brain Freeze ? READ MORE Read More What is acoustic neuroma? Identifying an AN Learn More Get Info ...

  10. NMR spectroscopic study and DFT calculations of GIAO NMR ...

    African Journals Online (AJOL)

    1H, proton coupled and decoupled 13C, DEPT, HETCOR NMR spectra, the magnitude of one bond 1JCH coupling constants and 13C NMR spin-lattice relaxation time (T1) of 1,9-diaminononane (danon, C9H22N2) have been reported for the first time. 1H, 13C NMR chemical shifts and 1JCH coupling constants of danon ...

  11. Solution NMR in structural genomics.

    Science.gov (United States)

    Yee, Adelinda; Gutmanas, Aleksandras; Arrowsmith, Cheryl H

    2006-10-01

    Structural genomics (also known as structural proteomics) aims to generate accurate three-dimensional models for all folded, globular proteins and domains in the protein universe to understand the relationship between protein sequence, structure and function. NMR spectroscopy of small (structural genomics projects for more than six years now. Recent advances coming from traditional NMR structural biology laboratories as well as large scale centers and consortia using NMR for structural genomics promise to facilitate NMR analysis making it even a more efficient and increasingly automated procedure.

  12. Magic Angle Spinning NMR Metabolomics

    Energy Technology Data Exchange (ETDEWEB)

    Zhi Hu, Jian

    2016-01-01

    Nuclear Magnetic Resonance (NMR) spectroscopy is a non-destructive, quantitative, reproducible, untargeted and unbiased method that requires no or minimal sample preparation, and is one of the leading analytical tools for metabonomics research [1-3]. The easy quantification and the no need of prior knowledge about compounds present in a sample associated with NMR are advantageous over other techniques [1,4]. 1H NMR is especially attractive because protons are present in virtually all metabolites and its NMR sensitivity is high, enabling the simultaneous identification and monitoring of a wide range of low molecular weight metabolites.

  13. Acoustic transducer

    Science.gov (United States)

    Drumheller, Douglas S.

    2000-01-01

    An active acoustic transducer tool for use down-hole applications. The tool includes a single cylindrical mandrel including a shoulder defining the boundary of a narrowed portion over which is placed a sandwich-style piezoelectric tranducer assembly. The piezoelectric transducer assembly is prestressed by being placed in a thermal interference fit between the shoulder of the mandrel and the base of an anvil which is likewise positioned over the narrower portion of the mandrel. In the preferred embodiment, assembly of the tool is accomplished using a hydraulic jack to stretch the mandrel prior to emplacement of the cylindrical sandwich-style piezoelectric transducer assembly and anvil. After those elements are positioned and secured, the stretched mandrel is allowed to return substantially to its original (pre-stretch) dimensions with the result that the piezoelectric transducer elements are compressed between the anvil and the shoulder of the mandrel.

  14. Use of acoustic vortices in acoustic levitation

    DEFF Research Database (Denmark)

    Cutanda Henriquez, Vicente; Santillan, Arturo Orozco; Juhl, Peter Møller

    2009-01-01

    Acoustic fields are known to exert forces on the surfaces of objects. These forces are noticeable if the sound pressure is sufficiently high. Two phenomena where acoustic forces are relevant are: i) acoustic levitation, where strong standing waves can hold small objects at certain positions......, counterbalancing their weight, and ii) acoustic vortices, spinning sound fields that can impinge angular momentum and cause rotation of objects. In this contribution, both force-creating sound fields are studied by means of numerical simulations. The Boundary Element Method is employed to this end. The simulation...... of acoustical vortices uses an efficient numerical implementation based on the superposition of two orthogonal sound fields with a delay of 90° between them. It is shown that acoustic levitation and the use of acoustic vortices can be combined to manipulate objects in an efficient and controlled manner without...

  15. Acoustic telemetry.

    Energy Technology Data Exchange (ETDEWEB)

    Drumheller, Douglas Schaeffer; Kuszmaul, Scott S.

    2003-08-01

    Broadcasting messages through the earth is a daunting task. Indeed, broadcasting a normal telephone conversion through the earth by wireless means is impossible with todays technology. Most of us don't care, but some do. Industries that drill into the earth need wireless communication to broadcast navigation parameters. This allows them to steer their drill bits. They also need information about the natural formation that they are drilling. Measurements of parameters such as pressure, temperature, and gamma radiation levels can tell them if they have found a valuable resource such as a geothermal reservoir or a stratum bearing natural gas. Wireless communication methods are available to the drilling industry. Information is broadcast via either pressure waves in the drilling fluid or electromagnetic waves in the earth and well tubing. Data transmission can only travel one way at rates around a few baud. Given that normal Internet telephone modems operate near 20,000 baud, these data rates are truly very slow. Moreover, communication is often interrupted or permanently blocked by drilling conditions or natural formation properties. Here we describe a tool that communicates with stress waves traveling through the steel drill pipe and production tubing in the well. It's based on an old idea called Acoustic Telemetry. But what we present here is more than an idea. This tool exists, it's drilled several wells, and it works. Currently, it's the first and only acoustic telemetry tool that can withstand the drilling environment. It broadcasts one way over a limited range at much faster rates than existing methods, but we also know how build a system that can communicate both up and down wells of indefinite length.

  16. NMR in pulsed magnetic field

    KAUST Repository

    Abou-Hamad, Edy

    2011-09-01

    Nuclear magnetic resonance (NMR) experiments in pulsed magnetic fields up to 30.4 T focused on 1H and 93Nb nuclei are reported. Here we discuss the advantage and limitation of pulsed field NMR and why this technique is able to become a promising research tool. © 2011 Elsevier Inc. All Rights Reserved.

  17. Fundamentals of Protein NMR Spectroscopy

    CERN Document Server

    Rule, Gordon S

    2006-01-01

    NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to the application and interpretation of modern multi-dimensional NMR experiments on 15N/13C-labeled proteins. Beginning with elementary quantum mechanics, a set of practical rules is presented and used to describe many commonly employed multi-dimensional, multi-nuclear NMR pulse sequences. A modular analysis of NMR pulse sequence building blocks also provides a basis for understanding and developing novel pulse programs. This text not only covers topics from chemical shift assignment to protein structure refinement, as well as the analysis of protein dynamics and chemical kinetics, but also provides a practical guide to many aspects of modern spectrometer hardware, sample preparation, experimental set-up, and data pr...

  18. Responsive acoustic surfaces

    DEFF Research Database (Denmark)

    Peters, Brady; Tamke, Martin; Nielsen, Stig Anton

    2011-01-01

    Acoustic performance is defined by the parameter of reverberation time; however, this does not capture the acoustic experience in some types of open plan spaces. As many working and learning activities now take place in open plan spaces, it is important to be able to understand and design...... for the acoustic conditions of these spaces. This paper describes an experimental research project that studied the design processes necessary to design for sound. A responsive acoustic surface was designed, fabricated and tested. This acoustic surface was designed to create specific sonic effects. The design...... was simulated using custom integrated acoustic software and also using Odeon acoustic analysis software. The research demonstrates a method for designing space- and sound-defining surfaces, defines the concept of acoustic subspace, and suggests some new parameters for defining acoustic subspaces....

  19. Springer Handbook of Acoustics

    CERN Document Server

    Rossing, Thomas D

    2007-01-01

    Acoustics, the science of sound, has developed into a broad interdisciplinary field encompassing the academic disciplines of physics, engineering, psychology, speech, audiology, music, architecture, physiology, neuroscience, and others. The Springer Handbook of Acoustics is an unparalleled modern handbook reflecting this richly interdisciplinary nature edited by one of the acknowledged masters in the field, Thomas Rossing. Researchers and students benefit from the comprehensive contents spanning: animal acoustics including infrasound and ultrasound, environmental noise control, music and human speech and singing, physiological and psychological acoustics, architectural acoustics, physical and engineering acoustics, signal processing, medical acoustics, and ocean acoustics. This handbook reviews the most important areas of acoustics, with emphasis on current research. The authors of the various chapters are all experts in their fields. Each chapter is richly illustrated with figures and tables. The latest rese...

  20. Applications of unilateral NMR in nondestructive testing

    OpenAIRE

    Sharma, Shatrughan

    2004-01-01

    In general, in NMR spectroscopy a sample is prepared for the NMR measurement, positioned in the magnet, measured, and discarded. But when non-destructiveness of the sample is more important, it becomes important to rely on relaxation analysis at low resolution NMR. If the samples are big in size the unilateral or single-sided NMR in inhomogeneous fields is an important choice. Unilateral NMR or inside-out NMR is one recognized technique in the field of low resolution NMR. The NMR-MOUSE (Mobil...

  1. Acoustic Neurinomas

    Directory of Open Access Journals (Sweden)

    Mohammad Faraji Rad

    2011-01-01

    Full Text Available Acoustic neuromas (AN are schwann cell-derived tumors that commonly arise from the vestibular portion of the eighth cranial nerve also known as vestibular schwannoma(VS causes unilateral hearing loss, tinnitus, vertigo and unsteadiness. In many cases, the tumor size may remain unchanged for many years following diagnosis, which is typically made by MRI. In the majority of cases the tumor is small, leaving the clinician and patient with the options of either serial scanning or active treatment by gamma knife radiosurgery (GKR or microneurosurgery. Despite the vast number of published treatment reports, comparative studies are few. The predominant clinical endpoints of AN treatment include tumor control, facial nerve function and hearing preservation. Less focus has been put on symptom relief and health-related quality of life (QOL. It is uncertain if treating a small tumor leaves the patient with a better chance of obtaining relief from future hearing loss, vertigo or tinnitus than by observing it without treatment.   In this paper we review the literature for the natural course, the treatment alternatives and the results of AN. Finally, we present our experience with a management strategy applied for more than 30 years.

  2. Acoustic Spatiality

    Directory of Open Access Journals (Sweden)

    Brandon LaBelle

    2012-06-01

    Full Text Available Experiences of listening can be appreciated as intensely relational, bringing us into contact with surrounding events, bodies and things. Given that sound propagates and expands outwardly, as a set of oscillations from a particular source, listening carries with it a sensual intensity, whereby auditory phenomena deliver intrusive and disruptive as well as soothing and assuring experiences. The physicality characteristic of sound suggests a deeply impressionistic, locational "knowledge structure" – that is, the ways in which listening affords processes of exchange, of being in the world, and from which we extend ourselves. Sound, as physical energy reflecting and absorbing into the materiality around us, and even one's self, provides a rich platform for understanding place and emplacement. Sound is always already a trace of location.Such features of auditory experience give suggestion for what I may call an acoustical paradigm – how sound sets in motion not only the material world but also the flows of the imagination, lending to forces of signification and social structure, and figuring us in relation to each other. The relationality of sound brings us into a steady web of interferences, each of which announces the promise or problematic of being somewhere.

  3. PT-Symmetric Acoustics

    Directory of Open Access Journals (Sweden)

    Xuefeng Zhu

    2014-09-01

    Full Text Available We introduce here the concept of acoustic parity-time (PT symmetry and demonstrate the extraordinary scattering characteristics of the acoustic PT medium. On the basis of exact calculations, we show how an acoustic PT-symmetric medium can become unidirectionally transparent at given frequencies. Combining such a PT-symmetric medium with transformation acoustics, we design two-dimensional symmetric acoustic cloaks that are unidirectionally invisible in a prescribed direction. Our results open new possibilities for designing functional acoustic devices with directional responses.

  4. Acoustic source for generating an acoustic beam

    Science.gov (United States)

    Vu, Cung Khac; Sinha, Dipen N.; Pantea, Cristian

    2016-05-31

    An acoustic source for generating an acoustic beam includes a housing; a plurality of spaced apart piezo-electric layers disposed within the housing; and a non-linear medium filling between the plurality of layers. Each of the plurality of piezoelectric layers is configured to generate an acoustic wave. The non-linear medium and the plurality of piezo-electric material layers have a matching impedance so as to enhance a transmission of the acoustic wave generated by each of plurality of layers through the remaining plurality of layers.

  5. Annual reports on NMR spectroscopy

    CERN Document Server

    Webb, Graham A; McCarthy, M J

    1995-01-01

    Over recent years, no other technique has grown to such importance as that of NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a means for the specialist and non-specialist alike to become familiar with new applications of the technique in all branches of chemistry, including biochemistry, and pharmaceutics. This volume focuses on theoretical aspects of NMR nuclear shielding and on applications of

  6. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... more... LOGIN CALENDAR DONATE NEWS Home Learn Back Learn about acoustic neuroma AN Facts What is acoustic ... Stories Keywords Shop ANA Discussion Forum About Back Learn more about ANA About ANA Mission, Vision & Values ...

  7. Tethys Acoustic Metadata Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Tethys database houses the metadata associated with the acoustic data collection efforts by the Passive Acoustic Group. These metadata include dates, locations...

  8. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... is acoustic neuroma? Diagnosing Symptoms Side Effects Keywords Questions to ask Choosing a healthcare provider Request a ... What is acoustic neuroma Diagnosing Symptoms Side effects Question To Ask Treatment Options Back Overview Observation Radiation ...

  9. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Facts What is acoustic neuroma? Diagnosing Symptoms Side Effects Keywords Questions to ask Choosing a healthcare provider ... Surgery What is acoustic neuroma Diagnosing Symptoms Side effects Question To Ask Treatment Options Back Overview Observation ...

  10. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... resource Click to learn more... LOGIN CALENDAR DONATE NEWS Home Learn Back Learn about acoustic neuroma AN ... sponsors Become a Sponsor Acoustic Neuroma Association Latest News Join / Renew Login Contact Us Become a Sponsor ...

  11. Atlantic Herring Acoustic Surveys

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NEFSC Advanced Sampling Technologies Research Group conducts annual fisheries acoustic surveys using state-of-the-art acoustic, midwater trawling, and underwater...

  12. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... more Click to learn more... LOGIN CALENDAR DONATE NEWS Home Learn Back Learn about acoustic neuroma AN ... a Sponsor Patient Events Acoustic Neuroma Association Latest News Join / Renew Login Contact Us Become a Sponsor ...

  13. NMR Studies of Polymer Nanocomposites

    National Research Council Canada - National Science Library

    Greenbaum, Steve

    2001-01-01

    .... The primary tool is pulsed field gradient NMR. A static field gradient method was developed which makes possible variable pressure diffusion measurement, and the application to the important fuel cell membrane NAFION constitute the first results...

  14. β-NMR sample optimization

    CERN Document Server

    Zakoucka, Eva

    2013-01-01

    During my summer student programme I was working on sample optimization for a new β-NMR project at the ISOLDE facility. The β-NMR technique is well-established in solid-state physics and just recently it is being introduced for applications in biochemistry and life sciences. The β-NMR collaboration will be applying for beam time to the INTC committee in September for three nuclei: Cu, Zn and Mg. Sample optimization for Mg was already performed last year during the summer student programme. Therefore sample optimization for Cu and Zn had to be completed as well for the project proposal. My part in the project was to perform thorough literature research on techniques studying Cu and Zn complexes in native conditions, search for relevant binding candidates for Cu and Zn applicable for ß-NMR and eventually evaluate selected binding candidates using UV-VIS spectrometry.

  15. Tutorial on architectural acoustics

    Science.gov (United States)

    Shaw, Neil; Talaske, Rick; Bistafa, Sylvio

    2002-11-01

    This tutorial is intended to provide an overview of current knowledge and practice in architectural acoustics. Topics covered will include basic concepts and history, acoustics of small rooms (small rooms for speech such as classrooms and meeting rooms, music studios, small critical listening spaces such as home theatres) and the acoustics of large rooms (larger assembly halls, auditoria, and performance halls).

  16. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available Acoustic Neuroma Association 600 Peachtree Parkway Suite 108 Cumming, GA 30041 770-205-8211 info@ANAUSA.org The world's #1 acoustic ... Shop ANA Leadership & Staff Annual Reports Acoustic Neuroma Association 600 Peachtree Parkway Suite 108 Cumming, GA 30041 ...

  17. Development of Two-Dimensional NMR

    Indian Academy of Sciences (India)

    IAS Admin

    Two-dimensional NMR, COSY,. NOESY, 2D MRI, biomolecular structure determination. The development of Fourier transform NMR in the mid. 1960's, did parallel processing of the collection of NMR data, increased the signal/noise ratio by two orders of magnitude and made it possible to record the proton NMR spectra of.

  18. Optical pumping and xenon NMR

    Energy Technology Data Exchange (ETDEWEB)

    Raftery, M. Daniel [Univ. of California, Berkeley, CA (United States)

    1991-11-01

    Nuclear Magnetic Resonance (NMR) spectroscopy of xenon has become an important tool for investigating a wide variety of materials, especially those with high surface area. The sensitivity of its chemical shift to environment, and its chemical inertness and adsorption properties make xenon a particularly useful NMR probe. This work discusses the application of optical pumping to enhance the sensitivity of xenon NMR experiments, thereby allowing them to be used in the study of systems with lower surface area. A novel method of optically-pumping 129Xe in low magnetic field below an NMR spectrometer and subsequent transfer of the gas to high magnetic field is described. NMR studies of the highly polarized gas adsorbed onto powdered samples with low to moderate surface areas are now possible. For instance, NMR studies of optically-pumped xenon adsorbed onto polyacrylic acid show that xenon has a large interaction with the surface. By modeling the low temperature data in terms of a sticking probability and the gas phase xenon-xenon interaction, the diffusion coefficient for xenon at the surface of the polymer is determined. The sensitivity enhancement afforded by optical pumping also allows the NMR observation of xenon thin films frozen onto the inner surfaces of different sample cells. The geometry of the thin films results in interesting line shapes that are due to the bulk magnetic susceptibility of xenon. Experiments are also described that combine optical pumping with optical detection for high sensitivity in low magnetic field to observe the quadrupoler evolution of 131 Xe spins at the surface of the pumping cells. In cells with macroscopic asymmetry, a residual quadrupolar interaction causes a splitting in the 131Xe NMR frequencies in bare Pyrex glass cells and cells with added hydrogen.

  19. Optical pumping and xenon NMR

    Energy Technology Data Exchange (ETDEWEB)

    Raftery, M.D.

    1991-11-01

    Nuclear Magnetic Resonance (NMR) spectroscopy of xenon has become an important tool for investigating a wide variety of materials, especially those with high surface area. The sensitivity of its chemical shift to environment, and its chemical inertness and adsorption properties make xenon a particularly useful NMR probe. This work discusses the application of optical pumping to enhance the sensitivity of xenon NMR experiments, thereby allowing them to be used in the study of systems with lower surface area. A novel method of optically-pumping [sup 129]Xe in low magnetic field below an NMR spectrometer and subsequent transfer of the gas to high magnetic field is described. NMR studies of the highly polarized gas adsorbed onto powdered samples with low to moderate surface areas are now possible. For instance, NMR studies of optically-pumped xenon adsorbed onto polyacrylic acid show that xenon has a large interaction with the surface. By modeling the low temperature data in terms of a sticking probability and the gas phase xenon-xenon interaction, the diffusion coefficient for xenon at the surface of the polymer is determined. The sensitivity enhancement afforded by optical pumping also allows the NMR observation of xenon thin films frozen onto the inner surfaces of different sample cells. The geometry of the thin films results in interesting line shapes that are due to the bulk magnetic susceptibility of xenon. Experiments are also described that combine optical pumping with optical detection for high sensitivity in low magnetic field to observe the quadrupoler evolution of 131 Xe spins at the surface of the pumping cells. In cells with macroscopic asymmetry, a residual quadrupolar interaction causes a splitting in the [sup 131]Xe NMR frequencies in bare Pyrex glass cells and cells with added hydrogen.

  20. A Methodology to Integrate Magnetic Resonance and Acoustic Measurements for Reservoir Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Parra, Jorge O.; Hackert, Chris L.; Collier, Hughbert A.; Bennett, Michael

    2002-01-29

    The objective of this project was to develop an advanced imaging method, including pore scale imaging, to integrate NMR techniques and acoustic measurements to improve predictability of the pay zone in hydrocarbon reservoirs. This is accomplished by extracting the fluid property parameters using NMR laboratory measurements and the elastic parameters of the rock matrix from acoustic measurements to create poroelastic models of different parts of the reservoir. Laboratory measurement techniques and core imaging are being linked with a balanced petrographical analysis of the core and theoretical model.

  1. A Methodology to Integrate Magnetic Resonance and Acoustic Measurements for Reservoir Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Parra, Ph.D., Jorge O.

    2002-06-10

    The objective of the project was to develop an advanced imaging method, including pore scale imaging, to integrate nuclear magnetic resonance (NMR) techniques and acoustic measurements to improve predictability of the pay zone in hydrocarbon reservoirs. This will be accomplished by extracting the fluid property parameters using NMR laboratory measurements and the elastic parameters of the rock matrix from acoustic measurements to create poroelastic models of different parts of the reservoir. Laboratory measurement techniques and core imaging were linked with a balanced petrographical analysis of cores and theoretical modeling.

  2. Medical applications of NMR imaging and NMR spectroscopy with stable isotopes. Summary

    Energy Technology Data Exchange (ETDEWEB)

    Matwiyoff, N.A.

    1983-01-01

    The current status of NMR imaging and NMR spectroscopy are summarized. For the most part examples from the March 1983 Puerto Rico symposium are used to illustrate the utility of NMR in medicine. 18 refs., 5 figs.

  3. AST Launch Vehicle Acoustics

    Science.gov (United States)

    Houston, Janice; Counter, D.; Giacomoni, D.

    2015-01-01

    The liftoff phase induces acoustic loading over a broad frequency range for a launch vehicle. These external acoustic environments are then used in the prediction of internal vibration responses of the vehicle and components which result in the qualification levels. Thus, predicting these liftoff acoustic (LOA) environments is critical to the design requirements of any launch vehicle. If there is a significant amount of uncertainty in the predictions or if acoustic mitigation options must be implemented, a subscale acoustic test is a feasible pre-launch test option to verify the LOA environments. The NASA Space Launch System (SLS) program initiated the Scale Model Acoustic Test (SMAT) to verify the predicted SLS LOA environments and to determine the acoustic reduction with an above deck water sound suppression system. The SMAT was conducted at Marshall Space Flight Center and the test article included a 5% scale SLS vehicle model, tower and Mobile Launcher. Acoustic and pressure data were measured by approximately 250 instruments. The SMAT liftoff acoustic results are presented, findings are discussed and a comparison is shown to the Ares I Scale Model Acoustic Test (ASMAT) results.

  4. Flow NMR of complex systems

    Energy Technology Data Exchange (ETDEWEB)

    Scheler, U.; Bagusat, F. [Leibniz-Inst. fuer Polymerforschung Dresden e.V., Dresden (Germany)

    2007-07-01

    A combination of NMR imaging and pulsed field gradient (PFG) NMR is applied to investigate flow. NMR longitudinal relaxation is used to generate contrast in a binary system of oil and water. The spatial distribution of each component and its flow pattern are measured separately. As a model a Couette cell with an additional area of high shear is used as model geometry. While a flat smooth interface is found at rest, the interface become bent under rotation, finally emulgation starts because of the velocity differences between the components. Flow from a submillimeter tube into a wide box and out of the box is investigated as well to understand shear-induced mixing and demixing. (orig.)

  5. NMR and dynamics of biopolymers

    Energy Technology Data Exchange (ETDEWEB)

    Lian, L.Y.; Barsukov, I.L. [Leicester Univ. (United Kingdom)

    1994-12-31

    Several basic experimental analytical NMR techniques that are frequently used for the qualitative and quantitative analysis of dynamic and exchange processes, focusing on proteins systems, are described: chemical exchange (slow exchange, fast exchange, intermediate exchange), heteronuclear relaxation measurements (relaxation parameters, strategy of relaxation data analysis, experimental results and examples, motional model interpretation of relaxation data, homonuclear relaxation); slow large-scale exchange and hydrogen-deuterium exchange are also studied: mechanisms of hydrogen exchange in a native protein, methods for measuring amide exchange rates by NMR, interpretation of amide exchange rates. 9 fig., 3 tab., 56 ref.

  6. Springer handbook of acoustics

    CERN Document Server

    2014-01-01

    Acoustics, the science of sound, has developed into a broad interdisciplinary field encompassing the academic disciplines of physics, engineering, psychology, speech, audiology, music, architecture, physiology, neuroscience, and electronics. The Springer Handbook of Acoustics is also in his 2nd edition an unparalleled modern handbook reflecting this richly interdisciplinary nature edited by one of the acknowledged masters in the field, Thomas Rossing. Researchers and students benefit from the comprehensive contents. This new edition of the Handbook features over 11 revised and expanded chapters, new illustrations, and 2 new chapters covering microphone arrays  and acoustic emission.  Updated chapters contain the latest research and applications in, e.g. sound propagation in the atmosphere, nonlinear acoustics in fluids, building and concert hall acoustics, signal processing, psychoacoustics, computer music, animal bioacousics, sound intensity, modal acoustics as well as new chapters on microphone arrays an...

  7. Vibro-acoustics

    CERN Document Server

    Nilsson, Anders

    2015-01-01

    This three-volume book gives a thorough and comprehensive presentation of vibration and acoustic theories. Different from traditional textbooks which typically deal with some aspects of either acoustic or vibration problems, it is unique of this book to combine those two correlated subjects together. Moreover, it provides fundamental analysis and mathematical descriptions for several crucial phenomena of Vibro-Acoustics which are quite useful in noise reduction, including how structures are excited, energy flows from an excitation point to a sound radiating surface, and finally how a structure radiates noise to a surrounding fluid. Many measurement results included in the text make the reading interesting and informative. Problems/questions are listed at the end of each chapter and the solutions are provided. This will help the readers to understand the topics of Vibro-Acoustics more deeply. The book should be of interest to anyone interested in sound and vibration, vehicle acoustics, ship acoustics and inter...

  8. Deep Water Ocean Acoustics

    Science.gov (United States)

    2016-08-03

    for including this in acoustic models . Experimental analysis is combined with model development to isolate specific physics and improve our...under- ice scattering, bathymetric diffraction and the application of the ocean acoustic Parabolic Equation to infrasound. 2. Tasks a. Task 1: Basin...of Japan received at the CTBTO HA03 station in Juan Fernandez Chile , are a treasure trove of long-range low frequency acoustic propagation. In

  9. Laboratory for Structural Acoustics

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Supports experimental research where acoustic radiation, scattering, and surface vibration measurements of fluid-loaded and non-fluid-loaded structures are...

  10. Localized Acoustic Surface Modes

    KAUST Repository

    Farhat, Mohamed

    2015-08-04

    We introduce the concept of localized acoustic surface modes (ASMs). We demonstrate that they are induced on a two-dimensional cylindrical rigid surface with subwavelength corrugations under excitation by an incident acoustic plane wave. Our results show that the corrugated rigid surface is acoustically equivalent to a cylindrical scatterer with uniform mass density that can be represented using a Drude-like model. This, indeed, suggests that plasmonic-like acoustic materials can be engineered with potential applications in various areas including sensing, imaging, and cloaking.

  11. Shallow Water Acoustic Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Supports experimental research where high-frequency acoustic scattering and surface vibration measurements of fluid-loaded and non-fluid-loaded structures...

  12. Handbook of Engineering Acoustics

    CERN Document Server

    Möser, Michael

    2013-01-01

    This book examines the physical background of engineering acoustics, focusing on empirically obtained engineering experience as well as on measurement techniques and engineering methods for prognostics. Its goal is not only to describe the state of art of engineering acoustics but also to give practical help to engineers in order to solve acoustic problems. It deals with the origin, the transmission and the methods of the abating different kinds of air-borne and structure-borne sounds caused by various mechanisms – from traffic to machinery and flow-induced sound. In addition the modern aspects of room and building acoustics, as well as psychoacoustics and active noise control, are covered.

  13. Acoustic Technology Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory contains an electro-magnetic worldwide data collection and field measurement capability in the area of acoustic technology. Outfitted by NASA Langley...

  14. Push-through Direction Injectin NMR Automation

    Science.gov (United States)

    Nuclear magnetic resonance (NMR) and mass spectrometry (MS) are the two major spectroscopic techniques successfully used in metabolomics studies. The non-invasive, quantitative and reproducible characteristics make NMR spectroscopy an excellent technique for detection of endogeno...

  15. Biomolecular NMR: Past and future.

    Science.gov (United States)

    Markley, John L; Westler, William Milo

    2017-08-15

    The editors of this special volume suggested this topic, presumably because of the perspective lent by our combined >90-year association with biomolecular NMR. What follows is our personal experience with the evolution of the field, which we hope will illustrate the trajectory of change over the years. As for the future, one can confidently predict that it will involve unexpected advances. Our narrative is colored by our experience in using the NMR Facility for Biomedical Studies at Carnegie-Mellon University (Pittsburgh) and in developing similar facilities at Purdue (1977-1984) and the University of Wisconsin-Madison (1984-). We have enjoyed developing NMR technology and making it available to collaborators and users of these facilities. Our group's association with the Biological Magnetic Resonance data Bank (BMRB) and with the Worldwide Protein Data Bank (wwPDB) has also been rewarding. Of course, many groups contributed to the early growth and development of biomolecular NMR, and our brief personal account certainly omits many important milestones. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Deuterium Exchange Kinetics by NMR.

    Science.gov (United States)

    Roper, G. C.

    1985-01-01

    Describes a physical chemistry experiment which allows such concepts as kinetics, catalysis, isotope shifts, coupling constants, and the use of nuclear magnetic resonance (NMR) for quantitative work to be covered in the same exercise. Background information, experimental procedures used, and typical results obtained are included. (JN)

  17. High resolution NMR theory and chemical applications

    CERN Document Server

    Becker, Edwin D

    1969-01-01

    High Resolution NMR: Theory and Chemical Applications focuses on the applications of nuclear magnetic resonance (NMR), as well as chemical shifts, lattices, and couplings. The book first offers information on the theory of NMR, including nuclear spin and magnetic moment, spin lattice relaxation, line widths, saturation, quantum mechanical description of NMR, and ringing. The text then ponders on instrumentation and techniques and chemical shifts. Discussions focus on the origin of chemical shifts, reference compounds, empirical correlations of chemical shifts, modulation and phase detection,

  18. Time domain NMR applied to food products

    NARCIS (Netherlands)

    Duynhoven, van J.P.M.; Voda, A.; Witek, M.M.; As, van H.

    2010-01-01

    Time-domain NMR is being used throughout all areas of food science and technology. A wide range of one- and two-dimensional relaxometric and diffusometric applications have been implemented on cost-effective, robust and easy-to-use benchtop NMR equipment. Time-domain NMR applications do not only

  19. Parametric Room Acoustic Workflows

    DEFF Research Database (Denmark)

    Parigi, Dario; Svidt, Kjeld; Molin, Erik

    2017-01-01

    The paper investigates and assesses different room acoustics software and the opportunities they offer to engage in parametric acoustics workflow and to influence architectural designs. The first step consists in the testing and benchmarking of different tools on the basis of accuracy, speed...

  20. Cochlear bionic acoustic metamaterials

    Science.gov (United States)

    Ma, Fuyin; Wu, Jiu Hui; Huang, Meng; Fu, Gang; Bai, Changan

    2014-11-01

    A design of bionic acoustic metamaterial and acoustic functional devices was proposed by employing the mammalian cochlear as a prototype. First, combined with the experimental data in previous literatures, it is pointed out that the cochlear hair cells and stereocilia cluster are a kind of natural biological acoustic metamaterials with the negative stiffness characteristics. Then, to design the acoustic functional devices conveniently in engineering application, a simplified parametric helical structure was proposed to replace actual irregular cochlea for bionic design, and based on the computational results of such a bionic parametric helical structure, it is suggested that the overall cochlear is a local resonant system with the negative dynamic effective mass characteristics. There are many potential applications in the bandboard energy recovery device, cochlear implant, and acoustic black hole.

  1. Acoustic Signals and Systems

    DEFF Research Database (Denmark)

    2008-01-01

    The Handbook of Signal Processing in Acoustics will compile the techniques and applications of signal processing as they are used in the many varied areas of Acoustics. The Handbook will emphasize the interdisciplinary nature of signal processing in acoustics. Each Section of the Handbook...... will present topics on signal processing which are important in a specific area of acoustics. These will be of interest to specialists in these areas because they will be presented from their technical perspective, rather than a generic engineering approach to signal processing. Non-specialists, or specialists...... from different areas, will find the self-contained chapters accessible and will be interested in the similarities and differences between the approaches and techniques used in different areas of acoustics....

  2. Ocean acoustic reverberation tomography.

    Science.gov (United States)

    Dunn, Robert A

    2015-12-01

    Seismic wide-angle imaging using ship-towed acoustic sources and networks of ocean bottom seismographs is a common technique for exploring earth structure beneath the oceans. In these studies, the recorded data are dominated by acoustic waves propagating as reverberations in the water column. For surveys with a small receiver spacing (e.g., ocean acoustic reverberation tomography, is developed that uses the travel times of direct and reflected waves to image ocean acoustic structure. Reverberation tomography offers an alternative approach for determining the structure of the oceans and advancing the understanding of ocean heat content and mixing processes. The technique has the potential for revealing small-scale ocean thermal structure over the entire vertical height of the water column and along long survey profiles or across three-dimensional volumes of the ocean. For realistic experimental geometries and data noise levels, the method can produce images of ocean sound speed on a smaller scale than traditional acoustic tomography.

  3. Computational Ocean Acoustics

    CERN Document Server

    Jensen, Finn B; Porter, Michael B; Schmidt, Henrik

    2011-01-01

    Since the mid-1970s, the computer has played an increasingly pivotal role in the field of ocean acoustics. Faster and less expensive than actual ocean experiments, and capable of accommodating the full complexity of the acoustic problem, numerical models are now standard research tools in ocean laboratories. The progress made in computational ocean acoustics over the last thirty years is summed up in this authoritative and innovatively illustrated new text. Written by some of the field's pioneers, all Fellows of the Acoustical Society of America, Computational Ocean Acoustics presents the latest numerical techniques for solving the wave equation in heterogeneous fluid–solid media. The authors discuss various computational schemes in detail, emphasizing the importance of theoretical foundations that lead directly to numerical implementations for real ocean environments. To further clarify the presentation, the fundamental propagation features of the techniques are illustrated in color. Computational Ocean A...

  4. nmr spectroscopic study and dft calculations of giao nmr shieldings

    African Journals Online (AJOL)

    Preferred Customer

    bond 1JCH coupling constants and 13C NMR spin-lattice relaxation time (T1) of 1,9-diaminononane (danon,. C9H22N2) ... The 13C spin-lattice relaxation time is the important experimental quantity for examining the dynamical ..... Montgomery, J.A.; Vreven, T.; Kudin, K.N.; Burant, J.C.; Millam, J.M.; Iyengar, S.S.;. Tomasi, J.

  5. Polymers under mechanical stress- an NMR investigation

    Energy Technology Data Exchange (ETDEWEB)

    Boehme, Ute; Scheler, Ulrich [Leibniz Institute of Polymer Research Dresden (Germany); Xu, Bo; Leisen, Johannes; Beckham, Haskell W. [Georgia Institute of Technology, Atlanta, Georgia (United States)

    2010-07-01

    Low-field NMR using permanent magnets in Halbach arrangements permit NMR investigation without the limits present in high-field NMR. The lower field in conjunction with confined stray field permit the application of NMR, in particular relaxation NMR in a stretching apparatus and a rheometer. Crystalline and amorphous fraction of semi-crystalline polymers are distinguished by their transverse relaxation times. Upon mechanical load the relaxation times of the amorphous fraction changes as seen in in-situ measurements on polypropylene rods. During the formation of a neck the crystalline fraction becomes more prominent.

  6. Acoustic Force Density Acting on Inhomogeneous Fluids in Acoustic Fields

    DEFF Research Database (Denmark)

    Karlsen, Jonas Tobias; Augustsson, Per; Bruus, Henrik

    2016-01-01

    We present a theory for the acoustic force density acting on inhomogeneous fluids in acoustic fields on time scales that are slow compared to the acoustic oscillation period. The acoustic force density depends on gradients in the density and compressibility of the fluid. For microfluidic systems...

  7. Parametric Room Acoustic workflows with real-time acoustic simulation

    DEFF Research Database (Denmark)

    Parigi, Dario

    2017-01-01

    The paper investigates and assesses the opportunities that real-time acoustic simulation offer to engage in parametric acoustics workflow and to influence architectural designs from early design stages......The paper investigates and assesses the opportunities that real-time acoustic simulation offer to engage in parametric acoustics workflow and to influence architectural designs from early design stages...

  8. PVT Degradation Studies: NMR Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Herman M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kouzes, Richard T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-06-06

    Under certain environmental conditions, polyvinyl toluene (PVT) plastic scintillator has been observed to undergo internal fogging. Nuclear magnetic resonance spectroscopy has been used to elucidate the state of water inside the PVT. The deuterium NMR results show that water absorbed by PVT under warm, humid conditions enters several distinct environments, and when the PVT is transferred from incubation to ambient temperature and humidity the water is lost on a time scale of a few hours from these samples. Most of the deuterium NMR peaks can be assigned to bulk liquid water, but almost 35% of the detected signal intensity is contained in a resonance that resembles spectra of water contained in nanometer-scale pores in mesoporous carbon.

  9. Sorption isotherm measurements by NMR.

    Science.gov (United States)

    Leisen, Johannes; Beckham, Haskell W; Benham, Michael

    2002-01-01

    An experimental setup is described for the automated recording of sorption isotherms by NMR experiments at precisely defined levels of relative humidity (RH). Implementation is demonstrated for a cotton fabric; Bloch decays. T1 and T2* relaxation times were measured at predefined steps of increasing and decreasing relative humidities (RHs) so that a complete isotherm of NMR properties was obtained. Bloch decays were analyzed by fitting to relaxation functions consisting or a slow- and a fast-relaxing component. The fraction of slow-relaxing component was greater than the fraction of sorbed moisture determined from gravimetric sorption data. The excess slow-relaxing component was attributed to plasticized segments of the formerly rigid cellulose matrix. T1 and T2* sorption isotherms exhibit hysteresis similar to gravimetric sorption isotherms. However, correlating RH to moisture content (MC) reveals that both relaxation constants depend only on MC, and not on the history of moisture exposure.

  10. NMR hyperpolarization techniques for biomedicine.

    Science.gov (United States)

    Nikolaou, Panayiotis; Goodson, Boyd M; Chekmenev, Eduard Y

    2015-02-16

    Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo molecular imaging modalities, ranging from functional imaging of the lungs to metabolic imaging of cancer. This Concept article explores selected advances in methods for the preparation and use of hyperpolarized contrast agents, many of which are already at or near the phase of their clinical validation in patients. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Translational illusion of acoustic sources by transformation acoustics.

    Science.gov (United States)

    Sun, Fei; Li, Shichao; He, Sailing

    2017-09-01

    An acoustic illusion of creating a translated acoustic source is designed by utilizing transformation acoustics. An acoustic source shifter (ASS) composed of layered acoustic metamaterials is designed to achieve such an illusion. A practical example where the ASS is made with naturally available materials is also given. Numerical simulations verify the performance of the proposed device. The designed ASS may have some applications in, e.g., anti-sonar detection.

  12. Predicting Acoustics in Class Rooms

    DEFF Research Database (Denmark)

    Christensen, Claus Lynge; Rindel, Jens Holger

    2005-01-01

    Typical class rooms have fairly simple geometries, even so room acoustics in this type of room is difficult to predict using today's room acoustic computer modeling software. The reasons why acoustics of class rooms are harder to predict than acoustics of complicated concert halls might...

  13. Acoustic streaming in microchannels

    DEFF Research Database (Denmark)

    Tribler, Peter Muller

    , the acoustic streaming flow, and the forces on suspended microparticles. The work is motivated by the application of particle focusing by acoustic radiation forces in medical, environmental and food sciences. Here acoustic streaming is most often unwanted, because it limits the focusability of particles...... oscillating plates. Furthermore, under general thermodynamic conditions, we derive the time-dependent first- and second-order equations for the conservation of mass, momentum, and energy. The coupling from fluid equations to particle motion is achieved through the expressions for the streaming-induced drag...

  14. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Back Learn more about ANA About ANA Mission, Vision & Values Shop ANA Leadership & Staff Annual Reports Acoustic ... 205-8211 info@ANAUSA.org About ANA Mission, Vision & Values Leadership & Staff Annual Reports Shop ANA Home ...

  15. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Provider List Member Portal Back Webinar Library Newsletter Library ... About Back Learn more about ANA About ANA Mission, Vision & Values Shop ANA Leadership & Staff Annual Reports Acoustic Neuroma Association 600 Peachtree ...

  16. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... a patient kit Treatment Options Overview Observation Radiation Surgery What is acoustic neuroma Diagnosing Symptoms Side effects ... To Ask Treatment Options Back Overview Observation Radiation Surgery Choosing a healthcare provider Request a patient kit ...

  17. Diagnosing Acoustic Neuroma

    Science.gov (United States)

    ... Values Leadership & Staff Annual Reports Shop ANA Home Learn Diagnosing English English Arabic Catalan Chinese (Simplified) Chinese (Traditional) Danish French German Greek Haitian Creole Hebrew Hindi Italian Japanese Korean Portuguese Romanian Spanish Diagnosing The diagnosis of an acoustic ...

  18. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Click to learn more... LOGIN CALENDAR DONATE NEWS Home Learn Back Learn about acoustic neuroma AN Facts ... Vision & Values Leadership & Staff Annual Reports Shop ANA Home Learn Educational Video Ronson and Kerri Albany Support ...

  19. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Click to learn more... LOGIN CALENDAR DONATE NEWS Home Learn Back Learn about acoustic neuroma AN Facts ... Vision & Values Leadership & Staff Annual Reports Shop ANA Home Learn Educational Video Howard of NJ Gloria hiking ...

  20. Acoustic Igniter Project

    Data.gov (United States)

    National Aeronautics and Space Administration — An acoustic igniter eliminates the need to use electrical energy to drive spark systems to initiate combustion in liquid-propellant rockets. It does not involve the...

  1. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Choosing a healthcare provider Request a patient kit Treatment Options Overview Observation Radiation Surgery What is acoustic neuroma Diagnosing Symptoms Side effects Question To Ask Treatment Options Back Overview Observation Radiation Surgery Choosing a ...

  2. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Mission, Vision & Values Shop ANA Leadership & Staff Annual Reports Acoustic Neuroma Association 600 Peachtree Parkway Suite 108 ... About ANA Mission, Vision & Values Leadership & Staff Annual Reports Shop ANA Home Learn Educational Video English English ...

  3. Acoustic imaging system

    Science.gov (United States)

    Smith, Richard W.

    1979-01-01

    An acoustic imaging system for displaying an object viewed by a moving array of transducers as the array is pivoted about a fixed point within a given plane. A plurality of transducers are fixedly positioned and equally spaced within a laterally extending array and operatively directed to transmit and receive acoustic signals along substantially parallel transmission paths. The transducers are sequentially activated along the array to transmit and receive acoustic signals according to a preestablished sequence. Means are provided for generating output voltages for each reception of an acoustic signal, corresponding to the coordinate position of the object viewed as the array is pivoted. Receptions from each of the transducers are presented on the same display at coordinates corresponding to the actual position of the object viewed to form a plane view of the object scanned.

  4. Acoustics Noise Test Cell

    Data.gov (United States)

    Federal Laboratory Consortium — The Acoustic Noise Test Cell at the NASA/Caltech Jet Propulsion Laboratory (JPL) is located adjacent to the large vibration system; both are located in a class 10K...

  5. Principles of musical acoustics

    CERN Document Server

    Hartmann, William M

    2013-01-01

    Principles of Musical Acoustics focuses on the basic principles in the science and technology of music. Musical examples and specific musical instruments demonstrate the principles. The book begins with a study of vibrations and waves, in that order. These topics constitute the basic physical properties of sound, one of two pillars supporting the science of musical acoustics. The second pillar is the human element, the physiological and psychological aspects of acoustical science. The perceptual topics include loudness, pitch, tone color, and localization of sound. With these two pillars in place, it is possible to go in a variety of directions. The book treats in turn, the topics of room acoustics, audio both analog and digital, broadcasting, and speech. It ends with chapters on the traditional musical instruments, organized by family. The mathematical level of this book assumes that the reader is familiar with elementary algebra. Trigonometric functions, logarithms and powers also appear in the book, but co...

  6. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... ANA About ANA Mission, Vision & Values Shop ANA Leadership & Staff Annual Reports Acoustic Neuroma Association 600 Peachtree ... info@ANAUSA.org About ANA Mission, Vision & Values Leadership & Staff Annual Reports Shop ANA Home Learn Educational ...

  7. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Learn more about ANA About ANA Mission, Vision & Values Shop ANA Leadership & Staff Annual Reports Acoustic Neuroma ... 8211 info@ANAUSA.org About ANA Mission, Vision & Values Leadership & Staff Annual Reports Shop ANA Home Learn ...

  8. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Educational Video Scott at the Grand Canyon Proton Center load more hold SHIFT key to load all load all Stay Connected with ANA Newly Diagnosed Living with AN Healthcare Providers Acoustic Neuroma Association Donate Now Newly Diagnosed ...

  9. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Click to learn more... LOGIN CALENDAR DONATE NEWS Home Learn Back Learn about acoustic neuroma AN Facts ... Vision & Values Leadership & Staff Annual Reports Shop ANA Home Learn Educational Video English English Arabic Catalan Chinese ( ...

  10. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Click to learn more... LOGIN CALENDAR DONATE NEWS Home Learn Back Learn about acoustic neuroma AN Facts ... Vision & Values Leadership & Staff Annual Reports Shop ANA Home Learn Educational Video Keck Medicine of USC ANWarriors ...

  11. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Suite 108 Cumming, GA 30041 770-205-8211 info@ANAUSA.org The world's #1 acoustic neuroma resource ... List Member Portal Webinar Library Newsletter Library Patient Info Booklets Member Login Research ANA Survey/Registry AN ...

  12. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Click to learn more... LOGIN EVENTS DONATE NEWS Home Learn Back Learn about acoustic neuroma AN Facts ... Vision & Values Leadership & Staff Annual Reports Shop ANA Home Learn Educational Video Scott at the Grand Canyon ...

  13. Autonomous Acoustic Receiver System

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Collects underwater acoustic data and oceanographic data. Data are recorded onboard an ocean buoy and can be telemetered to a remote ship or shore station...

  14. Acoustic ambient noise recorder

    Digital Repository Service at National Institute of Oceanography (India)

    Saran, A.K.; Navelkar, G.S.; Almeida, A.M.; More, S.R.; Chodankar, P.V.; Murty, C.S.

    with a robust outfit that can withstand high pressures and chemically corrosion resistant materials. Keeping these considerations in view, a CMOS micro-controller-based marine acoustic ambient noise recorder has been developed with a real time clock...

  15. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Request a patient kit Treatment Options Overview Observation Radiation Surgery What is acoustic neuroma Diagnosing Symptoms Side ... Question To Ask Treatment Options Back Overview Observation Radiation Surgery Choosing a healthcare provider Request a patient ...

  16. Thermal Acoustic Fatigue Apparatus

    Data.gov (United States)

    Federal Laboratory Consortium — The Thermal Acoustic Fatigue Apparatus (TAFA) is a progressive wave tube test facility that is used to test structures for dynamic response and sonic fatigue due to...

  17. Acoustic MIMO signal processing

    CERN Document Server

    Huang, Yiteng; Chen, Jingdong

    2006-01-01

    A timely and important book addressing a variety of acoustic signal processing problems under multiple-input multiple-output (MIMO) scenarios. It uniquely investigates these problems within a unified framework offering a novel and penetrating analysis.

  18. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... provider Request a patient kit Treatment Options Overview Observation Radiation Surgery What is acoustic neuroma Diagnosing Symptoms ... effects Question To Ask Treatment Options Back Overview Observation Radiation Surgery Choosing a healthcare provider Request a ...

  19. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Vision & Values Leadership & Staff Annual Reports Shop ANA ... AN Healthcare Providers Acoustic Neuroma Association Donate Now Newly Diagnosed What is AN? Request a Patient Kit Treatment Options Get Support Find a Provider Discussion Forum Contact ANA Join ...

  20. Anal acoustic reflectometry

    DEFF Research Database (Denmark)

    Mitchell, Peter J; Klarskov, Niels; Telford, Karen J

    2011-01-01

    Anal acoustic reflectometry is a new technique of assessing anal sphincter function. Five new variables reflecting anal canal function are measured: the opening and closing pressure, the opening and closing elastance, and hysteresis.......Anal acoustic reflectometry is a new technique of assessing anal sphincter function. Five new variables reflecting anal canal function are measured: the opening and closing pressure, the opening and closing elastance, and hysteresis....

  1. Deep Water Ocean Acoustics

    Science.gov (United States)

    2016-12-22

    Final Report 3. DATES COVERED (From - To) 7/1/15 to 12/22/16 4. TITLE AND SUBTITLE Deep Water Ocean Acoustics 5a. CONTRACT NUMBER...shortening of the water column); 2.) Explicitly defined the geo-acoustics so that both models had the same sponge ; 3.) Output the complete computational...chosen because this VLA was spaced at /2 at 250Hz and is therefore beamforming capable, covering the conjugate depth. An ambient noise model was

  2. Dynamic pulsed-field-gradient NMR

    CERN Document Server

    Sørland, Geir Humborstad

    2014-01-01

    Dealing with the basics, theory and applications of dynamic pulsed-field-gradient NMR NMR (PFG NMR), this book describes the essential theory behind diffusion in heterogeneous media that can be combined with NMR measurements to extract important information of the system being investigated. This information could be the surface to volume ratio, droplet size distribution in emulsions, brine profiles, fat content in food stuff, permeability/connectivity in porous materials and medical applications currently being developed. Besides theory and applications it will provide the readers with background knowledge on the experimental set-ups, and most important, deal with the pitfalls that are numerously present in work with PFG-NMR. How to analyze the NMR data and some important basic knowledge on the hardware will be explained, too.

  3. The future of NMR-based metabolomics.

    Science.gov (United States)

    Markley, John L; Brüschweiler, Rafael; Edison, Arthur S; Eghbalnia, Hamid R; Powers, Robert; Raftery, Daniel; Wishart, David S

    2017-02-01

    The two leading analytical approaches to metabolomics are mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. Although currently overshadowed by MS in terms of numbers of compounds resolved, NMR spectroscopy offers advantages both on its own and coupled with MS. NMR data are highly reproducible and quantitative over a wide dynamic range and are unmatched for determining structures of unknowns. NMR is adept at tracing metabolic pathways and fluxes using isotope labels. Moreover, NMR is non-destructive and can be utilized in vivo. NMR results have a proven track record of translating in vitro findings to in vivo clinical applications. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  4. An Inversion Recovery NMR Kinetics Experiment

    OpenAIRE

    Williams, Travis J.; Kershaw, Allan D.; Li, Vincent; Wu, Xinping

    2011-01-01

    A convenient laboratory experiment is described in which NMR magnetization transfer by inversion recovery is used to measure the kinetics and thermochemistry of amide bond rotation. The experiment utilizes Varian spectrometers with the VNMRJ 2.3 software, but can be easily adapted to any NMR platform. The procedures and sample data sets in this article will enable instructors to use inversion recovery as a laboratory activity in applied NMR classes and provide research students with a conveni...

  5. Applications of NMR in Dairy Research

    Directory of Open Access Journals (Sweden)

    Anthony D. Maher

    2014-03-01

    Full Text Available NMR is a robust analytical technique that has been employed to investigate the properties of many substances of agricultural relevance. NMR was first used to investigate the properties of milk in the 1950s and has since been employed in a wide range of studies; including properties analysis of specific milk proteins to metabolomics techniques used to monitor the health of dairy cows. In this brief review, we highlight the different uses of NMR in the dairy industry.

  6. observed by high pressure NMR and NQR

    Indian Academy of Sciences (India)

    Abstract. NMR and NQR studies on two interesting systems (URu2Si2, CeTIn5) were performed under high pressure. (1) URu2Si2: In the pressure range 3.0 to 8.3 kbar, we have observed new 29Si. NMR signals arising from the antiferromagnetic (AF) region besides the previously observed 29Si. NMR signals which come ...

  7. Spin-Exchange Pumped NMR Gyros

    CERN Document Server

    Walker, Thad G

    2016-01-01

    We present the basic theory governing spin-exchange pumped NMR gyros. We review the basic physics of spin-exchange collisions and relaxation as they pertain to precision NMR. We present a simple model of operation as an NMR oscillator and use it to analyze the dynamic response and noise properties of the oscillator. We discuss the primary systematic errors (differential alkali fields, quadrupole shifts, and offset drifts) that limit the bias stability, and discuss methods to minimize them. We give with a brief overview of a practical implementation and performance of an NMR gyro built by Northrop-Grumman Corporation, and conclude with some comments about future prospects.

  8. NMR spectroscopy using liquid crystal solvents

    CERN Document Server

    Emsley, JW

    2013-01-01

    NMR Spectroscopy using Liquid Crystal Solvents covers the importance of using a liquid crystal solvent in NMR to derive nuclear dipolar spin-spin coupling constants. This book is composed of ten chapters, and begins with a brief description of the features and benefits of liquid crystal in NMR spectroscopic analysis. The succeeding chapters deal with the mode of operation of nuclear spin Hamiltonian for partially oriented molecules and the analysis of NMR spectra of partially oriented molecules, as well as the determination of rigid molecule structure. These topics are followed by discussions

  9. NMR-Based Metabolomics of Oral Biofluids.

    Science.gov (United States)

    Schirra, Horst Joachim; Ford, Pauline J

    2017-01-01

    NMR-based metabolomics is an established technique for characterizing the metabolite profile of biological fluids and investigating how metabolite profiles change in response to biological and/or clinical stimuli. Thus, NMR-based metabolomics has the potential to discover biomarkers for diagnosis, prognosis, and/or therapy of clinical conditions, as well as to unravel the physiology underlying clinical conditions. Here, we describe a detailed protocol for NMR-based metabolomics of oral biofluids, including sample collection, sample handling, NMR data acquisition, and processing. In addition, we give a general overview of the statistical analysis of the resulting metabolomic data.

  10. Measuring acoustic habitats.

    Science.gov (United States)

    Merchant, Nathan D; Fristrup, Kurt M; Johnson, Mark P; Tyack, Peter L; Witt, Matthew J; Blondel, Philippe; Parks, Susan E

    2015-03-01

    1. Many organisms depend on sound for communication, predator/prey detection and navigation. The acoustic environment can therefore play an important role in ecosystem dynamics and evolution. A growing number of studies are documenting acoustic habitats and their influences on animal development, behaviour, physiology and spatial ecology, which has led to increasing demand for passive acoustic monitoring (PAM) expertise in the life sciences. However, as yet, there has been no synthesis of data processing methods for acoustic habitat monitoring, which presents an unnecessary obstacle to would-be PAM analysts. 2. Here, we review the signal processing techniques needed to produce calibrated measurements of terrestrial and aquatic acoustic habitats. We include a supplemental tutorial and template computer codes in matlab and r, which give detailed guidance on how to produce calibrated spectrograms and statistical analyses of sound levels. Key metrics and terminology for the characterisation of biotic, abiotic and anthropogenic sound are covered, and their application to relevant monitoring scenarios is illustrated through example data sets. To inform study design and hardware selection, we also include an up-to-date overview of terrestrial and aquatic PAM instruments. 3. Monitoring of acoustic habitats at large spatiotemporal scales is becoming possible through recent advances in PAM technology. This will enhance our understanding of the role of sound in the spatial ecology of acoustically sensitive species and inform spatial planning to mitigate the rising influence of anthropogenic noise in these ecosystems. As we demonstrate in this work, progress in these areas will depend upon the application of consistent and appropriate PAM methodologies.

  11. Acoustic comfort in eating establishments

    DEFF Research Database (Denmark)

    Svensson, David; Jeong, Cheol-Ho; Brunskog, Jonas

    2014-01-01

    The subjective concept of acoustic comfort in eating establishments has been investigated in this study. The goal was to develop a predictive model for the acoustic comfort, by means of simple objective parameters, while also examining which other subjective acoustic parameters could help explain...... the feeling of acoustic comfort. Through several layers of anal ysis, acoustic comfort was found to be rather complex, and could not be explained entirely by common subjective parameters such as annoyance, intelligibility or privacy. A predictive model for the mean acoustic comfort for an eating establishment...

  12. Interactions in an acoustic world

    CERN Document Server

    Simaciu, Ion; Borsos, Zoltan; Bradac, Mariana

    2016-01-01

    The present paper aims to complete an earlier paper where the acoustic world was introduced. This is accomplished by analyzing the interactions which occur between the inhomogeneities of the acoustic medium, which are induced by the acoustic vibrations traveling in the medium. When a wave packet travels in a medium, the medium becomes inhomogeneous. The spherical wave packet behaves like an acoustic spherical lens for the acoustic plane waves. According to the principle of causality, there is an interaction between the wave and plane wave packet. In specific conditions the wave packet behaves as an acoustic black hole.

  13. Access to NMR Spectroscopy for Two-Year College Students: The NMR Site at Trinity University

    Science.gov (United States)

    Mills, Nancy S.; Shanklin, Michael

    2011-01-01

    Students at two-year colleges and small four-year colleges have often obtained their exposure to NMR spectroscopy through "canned" spectra because the cost of an NMR spectrometer, particularly a high-field spectrometer, is prohibitive in these environments. This article describes the design of a NMR site at Trinity University in which…

  14. NMR studies of oriented molecules

    Energy Technology Data Exchange (ETDEWEB)

    Sinton, S.W.

    1981-11-01

    Deuterium and proton magnetic resonance are used in experiments on a number of compounds which either form liquid crystal mesophases themselves or are dissolved in a liquid crystal solvent. Proton multiple quantum NMR is used to simplify complicated spectra. The theory of nonselective multiple quantum NMR is briefly reviewed. Benzene dissolved in a liquid crystal are used to demonstrate several outcomes of the theory. Experimental studies include proton and deuterium single quantum (..delta..M = +-1) and proton multiple quantum spectra of several molecules which contain the biphenyl moiety. 4-Cyano-4'-n-pentyl-d/sub 11/-biphenyl (5CB-d/sub 11/) is studied as a pure compound in the nematic phase. The obtained chain order parameters and dipolar couplings agree closely with previous results. Models for the effective symmetry of the biphenyl group in 5CB-d/sub 11/ are tested against the experimental spectra. The dihedral angle, defined by the planes containing the rings of the biphenyl group, is found to be 30 +- 2/sup 0/ for 5DB-d/sub 11/. Experiments are also described for 4,4'-d/sub 2/-biphenyl, 4,4' - dibromo-biphenyl, and unsubstituted biphenyl.

  15. [Acoustic characteristics of classrooms].

    Science.gov (United States)

    Koszarny, Zbigniew; Chyla, Andrzej

    2003-01-01

    Quality and usefulness of school rooms for transmission of verbal information depends on the two basic parameters: form and quantity of the reverberation time, and profitable line measurements of school rooms from the acoustic point of view. An analysis of the above-mentioned parameters in 48 class rooms and two gymnasiums in schools, which were built in different periods, shows that the most important problem is connected with too long reverberation time and inappropriate acoustic proportions. In schools built in the 1970s, the length of reverberation time is mostly within a low frequency band, while in schools built contemporarily, the maximum length of disappearance time takes place in a quite wide band of 250-2000 Hz. This exceeds optimal values for that kind of rooms at least twice, and five times in the newly built school. A long reverberation time is connected with a low acoustic absorption of school rooms. Moreover, school rooms are characterised by inappropriate acoustic proportions. The classrooms, in their relation to the height, are too long and too wide. It is connected with deterioration of the transmission of verbal information. The data show that this transmission is unequal. Automatically, it leads to a speech disturbance and difficulties with understanding. There is the need for adaptation of school rooms through increase of an acoustic absorption.

  16. An Inversion Recovery NMR Kinetics Experiment

    Science.gov (United States)

    Williams, Travis J.; Kershaw, Allan D.; Li, Vincent; Wu, Xinping

    2011-01-01

    A convenient laboratory experiment is described in which NMR magnetization transfer by inversion recovery is used to measure the kinetics and thermochemistry of amide bond rotation. The experiment utilizes Varian spectrometers with the VNMRJ 2.3 software, but can be easily adapted to any NMR platform. The procedures and sample data sets in this…

  17. A Guided Inquiry Approach to NMR Spectroscopy

    Science.gov (United States)

    Parmentier, Laura E.; Lisensky, George C.; Spencer, Brock

    1998-04-01

    We present a novel way to introduce NMR spectroscopy into the general chemistry curriculum as part of a week-long aspirin project in our one-semester introductory course. Aspirin is synthesized by reacting salicylic acid and acetic anhydride. Purity is determined by titration and IR and NMR spectroscopy. Students compare IR and NMR spectra of their aspirin product to a series of reference spectra obtained by the class. Students are able to interpret the IR spectra of their aspirin using IR data from previous experiments. NMR is introduced by having students collect 1H NMR spectra of a series of reference compounds chosen to include some of the structural features of aspirin and compare spectra and structures of the reference compounds to develop a correlation chart for chemical shifts. This process is done in small groups using shared class data and is guided by a series of questions designed to relate the different kinds of hydrogen atoms to number and position of peaks in the NMR spectrum. Students then identify the peaks in the NMR spectrum of their aspirin product and relate percent purity by titration with spectral results and percent yield. This is an enjoyable project that combines the synthesis of a familiar material with a guided inquiry-based introduction to NMR spectroscopy.

  18. Synthesis and NMR Elucidation of Novel Pentacycloundecane ...

    African Journals Online (AJOL)

    Herein we report the synthesis and NMR elucidation of five novel pentacycloundecane (PCU)-derived short peptides as potential HIV protease inhibitors. 1H and 13C spectral analysis show major overlapping of methine resonance of the PCU 'cage' thereby making it extremely difficult to assign the NMR signals. Attachment ...

  19. An Integrated Laboratory Project in NMR Spectroscopy.

    Science.gov (United States)

    Hudson, Reggie L.; Pendley, Bradford D.

    1988-01-01

    Describes an advanced NMR project that can be done with a 60-MHz continuous-wave proton spectrometer. Points out the main purposes are to give students experience in second-order NMR analysis, the simplification of spectra by raising the frequency, and the effect of non-hydrogen nuclei on proton resonances. (MVL)

  20. Using Cloud Storage for NMR Data Distribution

    Science.gov (United States)

    Soulsby, David

    2012-01-01

    An approach using Google Groups as method for distributing student-acquired NMR data has been implemented. We describe how to configure NMR spectrometer software so that data is uploaded to a laboratory section specific Google Group, thereby removing bottlenecks associated with printing and processing at the spectrometer workstation. Outside of…

  1. Sea Turtle Acoustic Telemetry Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Acoustic transmitters attached to sea turtles captured in various fishing gear enable the animals to be passively tracked. Acoustic receivers set up in an array...

  2. A Century of Acoustic Metrology

    DEFF Research Database (Denmark)

    Rasmussen, Knud

    1998-01-01

    The development in acoustic measurement technique over the last century is reviewed with special emphasis on the metrological aspect.......The development in acoustic measurement technique over the last century is reviewed with special emphasis on the metrological aspect....

  3. Advanced Active Acoustics Lab (AAAL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Active Acoustics Lab (AAAL) is a state-of-the-art Undersea Warfare (USW) acoustic data analysis facility capable of both active and passive underwater...

  4. Practical acoustic emission testing

    CERN Document Server

    2016-01-01

    This book is intended for non-destructive testing (NDT) technicians who want to learn practical acoustic emission testing based on level 1 of ISO 9712 (Non-destructive testing – Qualification and certification of personnel) criteria. The essential aspects of ISO/DIS 18436-6 (Condition monitoring and diagnostics of machines – Requirements for training and certification of personnel, Part 6: Acoustic Emission) are explained, and readers can deepen their understanding with the help of practice exercises. This work presents the guiding principles of acoustic emission measurement, signal processing, algorithms for source location, measurement devices, applicability of testing methods, and measurement cases to support not only researchers in this field but also and especially NDT technicians.

  5. Seamount acoustic scattering

    Science.gov (United States)

    Boehlert, George W.

    The cover of the March 1 issue of Eos showed a time series of acoustic scattering above Southeast Hancock Seamount (29°48‧N, 178°05‧E) on July 17-18, 1984. In a comment on that cover Martin Hovland (Eos, August 2, p. 760) argued that gas or “other far reaching causes” may be involved in the observed acoustic signals. He favors a hypothesis that acoustic scattering observed above a seeping pockmark in the North Sea is a combination of bubbles, stable microbubbles, and pelagic organisms and infers that this may be a more general phenomenon and indeed plays a role in the attraction of organisms to seamounts

  6. Acoustics waves and oscillations

    CERN Document Server

    Sen, S.N.

    2013-01-01

    Parameters of acoustics presented in a logical and lucid style Physical principles discussed with mathematical formulations Importance of ultrasonic waves highlighted Dispersion of ultrasonic waves in viscous liquids explained This book presents the theory of waves and oscillations and various applications of acoustics in a logical and simple form. The physical principles have been explained with necessary mathematical formulation and supported by experimental layout wherever possible. Incorporating the classical view point all aspects of acoustic waves and oscillations have been discussed together with detailed elaboration of modern technological applications of sound. A separate chapter on ultrasonics emphasizes the importance of this branch of science in fundamental and applied research. In this edition a new chapter ''Hypersonic Velocity in Viscous Liquids as revealed from Brillouin Spectra'' has been added. The book is expected to present to its readers a comprehensive presentation of the subject matter...

  7. Carbon-13 NMR spectroscopy of biological systems

    CERN Document Server

    Beckmann, Nicolau

    1995-01-01

    This book is intended to provide an in-depth understanding of 13C NMR as a tool in biological research. 13C NMR has provided unique information concerning complex biological systems, from proteins and nucleic acids to animals and humans. The subjects addressed include multidimensional heteronuclear techniques for structural studies of molecules in the liquid and solid states, the investigation of interactions in model membranes, the elucidation of metabolic pathwaysin vitro and in vivo on animals, and noninvasive metabolic studies performed on humans. The book is a unique mix of NMR methods and biological applications which makes it a convenient reference for those interested in research in this interdisciplinary area of physics, chemistry, biology, and medicine.Key Features* An interdisciplinary text with emphasis on both 13C NMR methodology and the relevant biological and biomedical issues* State-of-the-art 13C NMR techniques are described; Whenever possible, their advantages over other approaches are empha...

  8. Challenges and perspectives in quantitative NMR.

    Science.gov (United States)

    Giraudeau, Patrick

    2017-01-01

    This perspective article summarizes, from the author's point of view at the beginning of 2016, the major challenges and perspectives in the field of quantitative NMR. The key concepts in quantitative NMR are first summarized; then, the most recent evolutions in terms of resolution and sensitivity are discussed, as well as some potential future research directions in this field. A particular focus is made on methodologies capable of boosting the resolution and sensitivity of quantitative NMR, which could open application perspectives in fields where the sample complexity and the analyte concentrations are particularly challenging. These include multi-dimensional quantitative NMR and hyperpolarization techniques such as para-hydrogen-induced polarization or dynamic nuclear polarization. Because quantitative NMR cannot be dissociated from the key concepts of analytical chemistry, i.e. trueness and precision, the methodological developments are systematically described together with their level of analytical performance. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  9. NMR and MRI apparatus and method

    Energy Technology Data Exchange (ETDEWEB)

    Clarke, John; Kelso, Nathan; Lee, SeungKyun; Moessle, Michael; Myers, Whittier; McDermott, Robert; ten Haken, Bernard; Pines, Alexander; Trabesinger, Andreas

    2007-03-06

    Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. Additional signal to noise benefits are obtained by use of a low noise polarization coil, comprising litz wire or superconducting materials. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

  10. Acoustic Liners for Turbine Engines

    Science.gov (United States)

    Jones, Michael G (Inventor); Grady, Joseph E (Inventor); Kiser, James D. (Inventor); Miller, Christopher (Inventor); Heidmann, James D. (Inventor)

    2016-01-01

    An improved acoustic liner for turbine engines is disclosed. The acoustic liner may include a straight cell section including a plurality of cells with straight chambers. The acoustic liner may also include a bent cell section including one or more cells that are bent to extend chamber length without increasing the overall height of the acoustic liner by the entire chamber length. In some cases, holes are placed between cell chambers in addition to bending the cells, or instead of bending the cells.

  11. Good acoustics central to recovery.

    Science.gov (United States)

    Budd, Richard

    2009-04-01

    Good acoustic conditions in hospitals and other healthcare facilities are known not only to benefit patients by creating an environment that facilitates rest, sleeping, consultation and treatment, but also clinical and nursing staff. At the recent Healthcare Estates conference, Richard Budd of acoustic engineering and noise and vibration consultants Sound Research Laboratories, discussed the revised guidance on good acoustic design in a recently published Health Technical Memorandum, HTM 08-01-Acoustics.

  12. NMR-based milk metabolomics

    DEFF Research Database (Denmark)

    Sundekilde, Ulrik; Larsen, Lotte Bach; Bertram, Hanne Christine S.

    2013-01-01

    Milk is a key component in infant nutrition worldwide and, in the Western parts of the world, also in adult nutrition. Milk of bovine origin is both consumed fresh and processed into a variety of dairy products including cheese, fermented milk products, and infant formula. The nutritional quality...... and processing capabilities of bovine milk is closely associated to milk composition. Metabolomics is ideal in the study of the low-molecular-weight compounds in milk, and this review focuses on the recent nuclear magnetic resonance (NMR)-based metabolomics trends in milk research, including applications linking...... the milk metabolite profiling with nutritional aspects, and applications which aim to link the milk metabolite profile to various technological qualities of milk. The metabolite profiling studies encompass the identification of novel metabolites, which potentially can be used as biomarkers or as bioactive...

  13. NMR studies of sedimentary tetrapyrroles

    Energy Technology Data Exchange (ETDEWEB)

    Keely, B.J.; Maxwell, J.R. (Univ. of Bristol (England))

    Structural assignments of sedimentary biological markers rely mostly on the use of GC and GC-MS techniques, involving both chromatographic and mass spectral comparisons with synthetic standards in addition to de facto mass spectral interpretation. Difficulties experienced in the analysis of sedimentary porphyrins by GC-MS (which until very recently required derivatization), and the desire to understand the origins and geochemical transformations of these components and their precursors, have led to more extensive structural investigations than usually accorded to other classes of biological marker. This paper briefly reviews recent developments in {sup 1}H NMR studies of chlorins and porphyrins of sedimentary origin, with particular reference to correlated spectroscopy (COSY), which allows elucidation of spin-coupled systems.

  14. NMR-based metabolomics applications

    DEFF Research Database (Denmark)

    Iaccarino, Nunzia

    ’s phenotype. This approach finds an increasing number of applications in many areas including medical, pharmaceutical, food and environmental sciences. The combined use of NMR spectroscopy and chemometrics techniques, is able to provide the metabolic “fingerprint” of the various samples. This PhD project...... focused on the analysis of various samples covering a wide range of fields, namely, food and nutraceutical sciences, cell metabolomics and medicine using a metabolomics approach. Indeed, the first part of the thesis describes two exploratory studies performed on Algerian extra virgin olive oil and apple...... juice from ancient Danish apple cultivars. Both studies revealed variety-related peculiarities that would have been difficult to detect by means of traditional analysis. The second part of the project includes four metabolomics studies performed on samples of biological origin. In particular, the first...

  15. Preprocessing of NMR metabolomics data.

    Science.gov (United States)

    Euceda, Leslie R; Giskeødegård, Guro F; Bathen, Tone F

    2015-05-01

    Metabolomics involves the large scale analysis of metabolites and thus, provides information regarding cellular processes in a biological sample. Independently of the analytical technique used, a vast amount of data is always acquired when carrying out metabolomics studies; this results in complex datasets with large amounts of variables. This type of data requires multivariate statistical analysis for its proper biological interpretation. Prior to multivariate analysis, preprocessing of the data must be carried out to remove unwanted variation such as instrumental or experimental artifacts. This review aims to outline the steps in the preprocessing of NMR metabolomics data and describe some of the methods to perform these. Since using different preprocessing methods may produce different results, it is important that an appropriate pipeline exists for the selection of the optimal combination of methods in the preprocessing workflow.

  16. Acoustically Induced Vibration of Structures: Reverberant Vs. Direct Acoustic Testing

    Science.gov (United States)

    Kolaini, Ali R.; O'Connell, Michael R.; Tsoi, Wan B.

    2009-01-01

    Large reverberant chambers have been used for several decades in the aerospace industry to test larger structures such as solar arrays and reflectors to qualify and to detect faults in the design and fabrication of spacecraft and satellites. In the past decade some companies have begun using direct near field acoustic testing, employing speakers, for qualifying larger structures. A limited test data set obtained from recent acoustic tests of the same hardware exposed to both direct and reverberant acoustic field testing has indicated some differences in the resulting structural responses. In reverberant acoustic testing, higher vibration responses were observed at lower frequencies when compared with the direct acoustic testing. In the case of direct near field acoustic testing higher vibration responses appeared to occur at higher frequencies as well. In reverberant chamber testing and direct acoustic testing, standing acoustic modes of the reverberant chamber or the speakers and spacecraft parallel surfaces can strongly couple with the fundamental structural modes of the test hardware. In this paper data from recent acoustic testing of flight hardware, that yielded evidence of acoustic standing wave coupling with structural responses, are discussed in some detail. Convincing evidence of the acoustic standing wave/structural coupling phenomenon will be discussed, citing observations from acoustic testing of a simple aluminum plate. The implications of such acoustic coupling to testing of sensitive flight hardware will be discussed. The results discussed in this paper reveal issues with over or under testing of flight hardware that could pose unanticipated structural and flight qualification issues. Therefore, it is of paramount importance to understand the structural modal coupling with standing acoustic waves that has been observed in both methods of acoustic testing. This study will assist the community to choose an appropriate testing method and test setup in

  17. Acoustic classification of dwellings

    DEFF Research Database (Denmark)

    Berardi, Umberto; Rasmussen, Birgit

    2014-01-01

    insulation performance, national schemes for sound classification of dwellings have been developed in several European countries. These schemes define acoustic classes according to different levels of sound insulation. Due to the lack of coordination among countries, a significant diversity in terms...... of descriptors, number of classes, and class intervals occurred between national schemes. However, a proposal “acoustic classification scheme for dwellings” has been developed recently in the European COST Action TU0901 with 32 member countries. This proposal has been accepted as an ISO work item. This paper...

  18. Carbon Nanotube Underwater Acoustic Thermophone

    Science.gov (United States)

    2016-09-23

    material (such as a piezoelectric ceramic , piezocomposite, or a magnetostrictive ferromagnetic compound). This electrical excitation creates a...Traditional acoustic transduction typically begins with the generation of electrical excitation pulsed through an amplifier into an electro-acoustic...mechanical vibration that is then converted into an acoustic wave to produce sound. The lower the preferred transmitting frequency (and hence a longer

  19. Fundamentals of Acoustics. Psychoacoustics and Hearing. Acoustical Measurements

    Science.gov (United States)

    Begault, Durand R.; Ahumada, Al (Technical Monitor)

    1997-01-01

    These are 3 chapters that will appear in a book titled "Building Acoustical Design", edited by Charles Salter. They are designed to introduce the reader to fundamental concepts of acoustics, particularly as they relate to the built environment. "Fundamentals of Acoustics" reviews basic concepts of sound waveform frequency, pressure, and phase. "Psychoacoustics and Hearing" discusses the human interpretation sound pressure as loudness, particularly as a function of frequency. "Acoustic Measurements" gives a simple overview of the time and frequency weightings for sound pressure measurements that are used in acoustical work.

  20. Evoked acoustic emission

    DEFF Research Database (Denmark)

    Elberling, C; Parbo, J; Johnsen, N J

    1985-01-01

    Stimulated acoustic emissions were recorded in response to tonal stimuli at 60 dB p.e. SPL in a small group of normal-hearing adults. Power spectral analysis reveals that the evoked activity from each ear contains energy in preferential frequency bands and the change of stimulus frequency has only...

  1. Underwater Acoustic Networking Techniques

    CERN Document Server

    Otnes, Roald; Casari, Paolo; Goetz, Michael; Husøy, Thor; Nissen, Ivor; Rimstad, Knut; van Walree, Paul; Zorzi, Michele

    2012-01-01

    This literature study presents an overview of underwater acoustic networking. It provides a background and describes the state of the art of all networking facets that are relevant for underwater applications. This report serves both as an introduction to the subject and as a summary of existing protocols, providing support and inspiration for the development of network architectures.

  2. Intelligent Engine Systems: Acoustics

    Science.gov (United States)

    Wojno, John; Martens, Steve; Simpson, Benjamin

    2008-01-01

    An extensive study of new fan exhaust nozzle technologies was performed. Three new uniform chevron nozzles were designed, based on extensive CFD analysis. Two new azimuthally varying variants were defined. All five were tested, along with two existing nozzles, on a representative model-scale, medium BPR exhaust nozzle. Substantial acoustic benefits were obtained from the uniform chevron nozzle designs, the best benefit being provided by an existing design. However, one of the azimuthally varying nozzle designs exhibited even better performance than any of the uniform chevron nozzles. In addition to the fan chevron nozzles, a new technology was demonstrated, using devices that enhance mixing when applied to an exhaust nozzle. The acoustic benefits from these devices applied to medium BPR nozzles were similar, and in some cases superior to, those obtained from conventional uniform chevron nozzles. However, none of the low noise technologies provided equivalent acoustic benefits on a model-scale high BPR exhaust nozzle, similar to current large commercial applications. New technologies must be identified to improve the acoustics of state-of-the-art high BPR jet engines.

  3. Deep Water Ocean Acoustics

    Science.gov (United States)

    2015-07-17

    Society of America 125 (4), 1394-1402 (2008). 2 J.W. Goodman , Introduction to Fourier Optics . (Roberts & Company, 2005). 3 George L Pickard and William...3 1. Introduction ...Report No. QSR-14C0172-Ocean Acoustics-063015 Technical Progress Report 1. Introduction The goal of this research is to increase our understanding

  4. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Surgery What is acoustic neuroma Diagnosing Symptoms Side effects ... Groups Is a support group for me? Find a Group Upcoming Events Video Library Photo Gallery One-on-One Support ANetwork Peer Support Program Community Connections Overview Find a Meeting ...

  5. Select Internet Resources on Acoustics

    Directory of Open Access Journals (Sweden)

    Angela R. Davis

    2016-12-01

    Full Text Available Merriam-Webster (2016 defines acoustics as, “a science that deals with the production, control, transmission, reception, and effects of sounds.” According to Rossing (2014, the study of acoustics began in ancient Greece with Pythagoras’ study of vibrating strings on musical instruments. Since those early beginnings, famous scientists including Rayleigh, Alexander Graham Bell, and Thomas Edison, have helped expand the field of acoustics to include architectural, physical, engineering, structural, underwater, physiological and psychological, musical acoustics, and speech. Acoustics is a highly interdisciplinary field and researchers may need resources from physics, medicine, and engineering to understand all aspects of their research.

  6. Holograms for acoustics.

    Science.gov (United States)

    Melde, Kai; Mark, Andrew G; Qiu, Tian; Fischer, Peer

    2016-09-22

    Holographic techniques are fundamental to applications such as volumetric displays, high-density data storage and optical tweezers that require spatial control of intricate optical or acoustic fields within a three-dimensional volume. The basis of holography is spatial storage of the phase and/or amplitude profile of the desired wavefront in a manner that allows that wavefront to be reconstructed by interference when the hologram is illuminated with a suitable coherent source. Modern computer-generated holography skips the process of recording a hologram from a physical scene, and instead calculates the required phase profile before rendering it for reconstruction. In ultrasound applications, the phase profile is typically generated by discrete and independently driven ultrasound sources; however, these can only be used in small numbers, which limits the complexity or degrees of freedom that can be attained in the wavefront. Here we introduce monolithic acoustic holograms, which can reconstruct diffraction-limited acoustic pressure fields and thus arbitrary ultrasound beams. We use rapid fabrication to craft the holograms and achieve reconstruction degrees of freedom two orders of magnitude higher than commercial phased array sources. The technique is inexpensive, appropriate for both transmission and reflection elements, and scales well to higher information content, larger aperture size and higher power. The complex three-dimensional pressure and phase distributions produced by these acoustic holograms allow us to demonstrate new approaches to controlled ultrasonic manipulation of solids in water, and of liquids and solids in air. We expect that acoustic holograms will enable new capabilities in beam-steering and the contactless transfer of power, improve medical imaging, and drive new applications of ultrasound.

  7. Acoustic field modulation in regenerators

    Science.gov (United States)

    Hu, J. Y.; Wang, W.; Luo, E. C.; Chen, Y. Y.

    2016-12-01

    The regenerator is a key component that transfers energy between heat and work. The conversion efficiency is significantly influenced by the acoustic field in the regenerator. Much effort has been spent to quantitatively determine this influence, but few comprehensive experimental verifications have been performed because of difficulties in modulating and measuring the acoustic field. In this paper, a method requiring two compressors is introduced and theoretically investigated that achieves acoustic field modulation in the regenerator. One compressor outputs the acoustic power for the regenerator; the other acts as a phase shifter. A RC load dissipates the acoustic power out of both the regenerator and the latter compressor. The acoustic field can be modulated by adjusting the current in the two compressors and opening the RC load. The acoustic field is measured with pressure sensors instead of flow-field imaging equipment, thereby greatly simplifying the experiment.

  8. Controlling sound with acoustic metamaterials

    DEFF Research Database (Denmark)

    Cummer, Steven A. ; Christensen, Johan; Alù, Andrea

    2016-01-01

    -scale metamaterial structures and converting laboratory experiments into useful devices. In this Review, we outline the designs and properties of materials with unusual acoustic parameters (for example, negative refractive index), discuss examples of extreme manipulation of sound and, finally, provide an overview......Acoustic metamaterials can manipulate and control sound waves in ways that are not possible in conventional materials. Metamaterials with zero, or even negative, refractive index for sound offer new possibilities for acoustic imaging and for the control of sound at subwavelength scales....... The combination of transformation acoustics theory and highly anisotropic acoustic metamaterials enables precise control over the deformation of sound fields, which can be used, for example, to hide or cloak objects from incident acoustic energy. Active acoustic metamaterials use external control to create...

  9. Scalar operators in solid-state NMR

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Boqin [Univ. of California, Berkeley, CA (United States)

    1991-11-01

    Selectivity and resolution of solid-state NMR spectra are determined by dispersion of local magnetic fields originating from relaxation effects and orientation-dependent resonant frequencies of spin nuclei. Theoretically, the orientation-dependent resonant frequencies can be represented by a set of irreducible tensors. Among these tensors, only zero rank tensors (scalar operators) are capable of providing high resolution NMR spectra. This thesis presents a series of new developments in high resolution solid-state NMR concerning the reconstruction of various scalar operators motion in solid C60 is analyzed.

  10. Graphical programming for broadband pulse NMR spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Belmonte, S.B. [Universidade do Estado (UERJ), Rio de Janeiro, RJ (Brazil). Dept. de Engenharia Eletronica; Oliveira, I.S.; Guimaraes, A.P. [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil)

    1997-12-31

    In a broadband pulsed nuclear magnetic resonance (NMR) spectrometer we often need to sweep the excitation frequency over a wide range, and acquire the spin echo components in quadrature for further spectral analysis. Computer languages such as C or Pascal have been traditionally applied to the development of software control of laboratory equipment, and consequently, the automatization of NMR experiments. However, the use of graphical languages have proved to be a flexible and convenient way for experiment and data acquisition control. In our application we use the graphical language Labview for the automatic control of a broadband pulse NMR spectrometer, dedicated to the study of magnetic metal systems. (author) 2 refs., 2 figs.

  11. Graphical programming for pulse automated NMR experiments

    Energy Technology Data Exchange (ETDEWEB)

    Belmonte, S.B. [Universidade do Estado, Rio de Janeiro, RJ (Brazil); Oliveira, I.S.; Guimaraes, A.P. [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil)

    1999-01-01

    We describe a software program designed to control a broadband pulse Nuclear Magnetic Resonance (NMR) spectrometer used in zero-field NMR studies of magnetic metals. The software is written in the graphical language LabVIEW. This type of programming allows modifications and the inclusion of new routines to be easily made by the non-specialist, without changing the basic structure of the program. The program corrects for differences in the gain of the two acquisition channels [U (phase) and V (quadrature)], and automatic baseline subtraction. We present examples of measurements of NMR spectra, spin-echo decay (T{sub 2}), and quadrupolar oscillations, performed in magnetic intermetallic compounds. (author)

  12. NMR reaction monitoring in flow synthesis

    Directory of Open Access Journals (Sweden)

    M. Victoria Gomez

    2017-02-01

    Full Text Available Recent advances in the use of flow chemistry with in-line and on-line analysis by NMR are presented. The use of macro- and microreactors, coupled with standard and custom made NMR probes involving microcoils, incorporated into high resolution and benchtop NMR instruments is reviewed. Some recent selected applications have been collected, including synthetic applications, the determination of the kinetic and thermodynamic parameters and reaction optimization, even in single experiments and on the μL scale. Finally, software that allows automatic reaction monitoring and optimization is discussed.

  13. Oriented solid-state NMR spectrosocpy

    DEFF Research Database (Denmark)

    Bertelsen, Kresten

    This thesis is concerned with driving forward oriented solid-state NMR spectroscopy as a viable technique for studying peptides in membrane bilayers. I will show that structural heterogeneity is an intrinsic part of the peptide/lipid system and that NMR can be used to characterize static...... and dynamic structural features of the peptides and its local surroundings. In fact one need to take into account the dynamical features of the system in order to correctly predict the structure from oriented solid-state NMR spectra.      ...

  14. Rheology of Blood by NMR

    Science.gov (United States)

    Han, Song-I.; Marseille, Oliver; Gehlen, Christa; Blümich, Bernhard

    2001-09-01

    Pipe flow of blood in tubes of 1 and 7 mm inner diameter, respectively, was investigated employing two-dimensional NMR velocity imaging and PFG propagator measurements at different Reynolds numbers between 10 and 3500. The results are compared to flow of a water/glycerol mixture of matching viscosity under identical conditions. The transition from laminar to turbulent flow is observed by both a flattening of the velocity profile and a change of the propagator shape. For blood flow this transition is found to be shifted toward higher Reynolds numbers as compared to the transition of the water/glycerol mixture. This observation is in agreement with predictions from hydraulic measurements and is a consequence of the non-Newtonian flow characteristics of blood as a suspension of erythrocytes and plasma. Likewise, a deviation from the laminar flow condition is observed for blood at low Reynolds numbers between 10 and 100. This phenomenon is unknown for Newtonian liquids and is explained by the onset of a geometrical arrangement of the erythrocytes, the so-called rouleaux effect.

  15. Development of Two-Dimensional NMR

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 11. Development of Two-Dimensional NMR: Strucure Determination of Biomolecules in Solution. Anil Kumar. General Article Volume 20 Issue 11 November 2015 pp 995-1002 ...

  16. Bayesian Peak Picking for NMR Spectra

    Directory of Open Access Journals (Sweden)

    Yichen Cheng

    2014-02-01

    Full Text Available Protein structure determination is a very important topic in structural genomics, which helps people to understand varieties of biological functions such as protein-protein interactions, protein–DNA interactions and so on. Nowadays, nuclear magnetic resonance (NMR has often been used to determine the three-dimensional structures of protein in vivo. This study aims to automate the peak picking step, the most important and tricky step in NMR structure determination. We propose to model the NMR spectrum by a mixture of bivariate Gaussian densities and use the stochastic approximation Monte Carlo algorithm as the computational tool to solve the problem. Under the Bayesian framework, the peak picking problem is casted as a variable selection problem. The proposed method can automatically distinguish true peaks from false ones without preprocessing the data. To the best of our knowledge, this is the first effort in the literature that tackles the peak picking problem for NMR spectrum data using Bayesian method.

  17. NMR analysis of compositional heterogeneity in polysaccharides

    Science.gov (United States)

    Many copolysaccharides are compositionally heterogeneous, and the composition determined by the usual analytical or spectroscopic methods provides only an average value. For some polysaccharides, the NMR data contain copolymer sequence information, such as diad, triad, and tetrad sequence intensiti...

  18. Relaxation time estimation in surface NMR

    Energy Technology Data Exchange (ETDEWEB)

    Grunewald, Elliot D.; Walsh, David O.

    2017-03-21

    NMR relaxation time estimation methods and corresponding apparatus generate two or more alternating current transmit pulses with arbitrary amplitudes, time delays, and relative phases; apply a surface NMR acquisition scheme in which initial preparatory pulses, the properties of which may be fixed across a set of multiple acquisition sequence, are transmitted at the start of each acquisition sequence and are followed by one or more depth sensitive pulses, the pulse moments of which are varied across the set of multiple acquisition sequences; and apply processing techniques in which recorded NMR response data are used to estimate NMR properties and the relaxation times T.sub.1 and T.sub.2* as a function of position as well as one-dimensional and two-dimension distributions of T.sub.1 versus T.sub.2* as a function of subsurface position.

  19. Bayesian Peak Picking for NMR Spectra

    KAUST Repository

    Cheng, Yichen

    2014-02-01

    Protein structure determination is a very important topic in structural genomics, which helps people to understand varieties of biological functions such as protein-protein interactions, protein–DNA interactions and so on. Nowadays, nuclear magnetic resonance (NMR) has often been used to determine the three-dimensional structures of protein in vivo. This study aims to automate the peak picking step, the most important and tricky step in NMR structure determination. We propose to model the NMR spectrum by a mixture of bivariate Gaussian densities and use the stochastic approximation Monte Carlo algorithm as the computational tool to solve the problem. Under the Bayesian framework, the peak picking problem is casted as a variable selection problem. The proposed method can automatically distinguish true peaks from false ones without preprocessing the data. To the best of our knowledge, this is the first effort in the literature that tackles the peak picking problem for NMR spectrum data using Bayesian method.

  20. The eNMR platform for structural biology

    NARCIS (Netherlands)

    Bonvin, A.M.J.J.|info:eu-repo/dai/nl/113691238; Rosato, A.; Wassenaar, T.A.|info:eu-repo/dai/nl/297077775

    2010-01-01

    The e-NMR project is a European cooperation initiative that aims at providing the bio-NMR user community with a software platform integrating and streamlining the computational approaches necessary for the analysis of bio-NMR data. The e-NMR platform is based on a Grid computational infrastructure.

  1. Frontiers of NMR in Molecular Biology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-08-25

    NMR spectroscopy is expanding the horizons of structural biology by determining the structures and describing the dynamics of blobular proteins in aqueous solution, as well as other classes of proteins including membrane proteins and the polypeptides that form the aggregates diagnostic of prion and amyloid diseases. Significant results are also emerging on DNA and RNA oligomers and their complexes with proteins. This meeting focused attention on key structural questions emanating from molecular biology and how NMR spectroscopy can be used to answer them.

  2. NMR studies of multiphase flows II

    Energy Technology Data Exchange (ETDEWEB)

    Altobelli, S.A.; Caprihan, A.; Fukushima, E. [Lovelace Institutes, Albuquerque, NM (United States)] [and others

    1995-12-31

    NMR techniques for measurements of spatial distribution of material phase, velocity and velocity fluctuation are being developed and refined. Versions of these techniques which provide time average liquid fraction and fluid phase velocity have been applied to several concentrated suspension systems which will not be discussed extensively here. Technical developments required to further extend the use of NMR to the multi-phase flow arena and to provide measurements of previously unobtainable parameters are the focus of this report.

  3. Physiological monitoring during nmr measurements of animals

    Science.gov (United States)

    Schmidt, Paul G.; Smith, E. Norbert

    With the introduction of whole animal NMR, simultaneous measurement of various physiological parameters becomes desirable. Described is a system for monitoring body temperature, electrocardiogram, and respiration during surface coil measurement of 31P NMR using unanesthetized animals. Passive filtering is used to remove rf pulses from the physiological signals. Provision is made for electrically stimulating the animal. The principles are adaptable to other physiological parameters, and the probe could be modified for other nuclei.

  4. Acoustic levitation of an object larger than the acoustic wavelength.

    Science.gov (United States)

    Andrade, Marco A B; Okina, Fábio T A; Bernassau, Anne L; Adamowski, Julio C

    2017-06-01

    Levitation and manipulation of objects by sound waves have a wide range of applications in chemistry, biology, material sciences, and engineering. However, the current acoustic levitation techniques are mainly restricted to particles that are much smaller than the acoustic wavelength. In this work, it is shown that acoustic standing waves can be employed to stably levitate an object much larger than the acoustic wavelength in air. The levitation of a large slightly curved object weighting 2.3 g is demonstrated by using a device formed by two 25 kHz ultrasonic Langevin transducers connected to an aluminum plate. The sound wave emitted by the device provides a vertical acoustic radiation force to counteract gravity and a lateral restoring force that ensure horizontal stability to the levitated object. In order to understand the levitation stability, a numerical model based on the finite element method is used to determine the acoustic radiation force that acts on the object.

  5. Flat acoustic lens by acoustic grating with curled slits

    KAUST Repository

    Peng, Pai

    2014-10-01

    We design a flat sub-wavelength lens that can focus acoustic wave. We analytically study the transmission through an acoustic grating with curled slits, which can serve as a material with tunable impedance and refractive index for acoustic waves. The effective parameters rely on the geometry of the slits and are independent of frequency. A flat acoustic focusing lens by such acoustic grating with gradient effective refractive index is designed. The focusing effect is clearly observed in simulations and well predicted by the theory. We demonstrate that despite the large impedance mismatch between the acoustic lens and the matrix, the intensity at the focal point is still high due to Fabry-Perot resonance.

  6. NMRbox: A Resource for Biomolecular NMR Computation.

    Science.gov (United States)

    Maciejewski, Mark W; Schuyler, Adam D; Gryk, Michael R; Moraru, Ion I; Romero, Pedro R; Ulrich, Eldon L; Eghbalnia, Hamid R; Livny, Miron; Delaglio, Frank; Hoch, Jeffrey C

    2017-04-25

    Advances in computation have been enabling many recent advances in biomolecular applications of NMR. Due to the wide diversity of applications of NMR, the number and variety of software packages for processing and analyzing NMR data is quite large, with labs relying on dozens, if not hundreds of software packages. Discovery, acquisition, installation, and maintenance of all these packages is a burdensome task. Because the majority of software packages originate in academic labs, persistence of the software is compromised when developers graduate, funding ceases, or investigators turn to other projects. To simplify access to and use of biomolecular NMR software, foster persistence, and enhance reproducibility of computational workflows, we have developed NMRbox, a shared resource for NMR software and computation. NMRbox employs virtualization to provide a comprehensive software environment preconfigured with hundreds of software packages, available as a downloadable virtual machine or as a Platform-as-a-Service supported by a dedicated compute cloud. Ongoing development includes a metadata harvester to regularize, annotate, and preserve workflows and facilitate and enhance data depositions to BioMagResBank, and tools for Bayesian inference to enhance the robustness and extensibility of computational analyses. In addition to facilitating use and preservation of the rich and dynamic software environment for biomolecular NMR, NMRbox fosters the development and deployment of a new class of metasoftware packages. NMRbox is freely available to not-for-profit users. Copyright © 2017 Biophysical Society. All rights reserved.

  7. Fundamentals of Physical Acoustics

    OpenAIRE

    Leclaire, Philippe

    2001-01-01

    Book review: Fundamentals of Physical Acoustics D.T. Blackstock; Wiley & Sons Ltd, New York, 2000, 541 pages, ISBN 0-471-3197; This book is an excellent piece of work. The text is extremely clear and goes a long way towards meeting the declared pedagogical target. The author has written a comprehensive text. The proportions of equations and explanations/interpretations are particularly well balanced. Throughout the book, the context and the validity domain for any equation derived are clearly...

  8. Ion Acoustic Microscopy

    Science.gov (United States)

    1985-07-01

    Murphy and L. C. Aamodt , "Signal Enhancement in Photothermal Imaging Produced by Three Dimensional Heat Flow", Appl. Phys. Lett. 39, 519 (1981); L. C... Aamodt and J. C. Murphy, "Photothermal Measurements Using a Localized Excitation Source", J. Appl. Phys. 52, 4903 (1981) (9) R. L. Thomas, L. D. Favro...25 (23) J. C. Murphy, F. G. Satkiewicz and L. C. Aamodt , "Ion Acoustic Imaging of Buried Flaws in Aluminum", Review of Progress in Quantitative NDE

  9. Acoustic emission source modeling

    Directory of Open Access Journals (Sweden)

    Hora P.

    2010-07-01

    Full Text Available The paper deals with the acoustic emission (AE source modeling by means of FEM system COMSOL Multiphysics. The following types of sources are used: the spatially concentrated force and the double forces (dipole. The pulse excitation is studied in both cases. As a material is used steel. The computed displacements are compared with the exact analytical solution of point sources under consideration.

  10. Fast wideband acoustical holography.

    Science.gov (United States)

    Hald, Jørgen

    2016-04-01

    Patch near-field acoustical holography methods like statistically optimized near-field acoustical holography and equivalent source method are limited to relatively low frequencies, where the average array-element spacing is less than half of the acoustic wavelength, while beamforming provides useful resolution only at medium-to-high frequencies. With adequate array design, both methods can be used with the same array. But for holography to provide good low-frequency resolution, a small measurement distance is needed, whereas beamforming requires a larger distance to limit sidelobe issues. The wideband holography method of the present paper was developed to overcome that practical conflict. Only a single measurement is needed at a relatively short distance and a single result is obtained covering the full frequency range. The method uses the principles of compressed sensing: A sparse sound field representation is assumed with a chosen set of basis functions, a measurement is taken with an irregular array, and the inverse problem is solved with a method that enforces sparsity in the coefficient vector. Instead of using regularization based on the 1-norm of the coefficient vector, an iterative solution procedure is used that promotes sparsity. The iterative method is shown to provide very similar results in most cases and to be computationally much more efficient.

  11. Spatiotemporally resolved granular acoustics

    Science.gov (United States)

    Owens, Eli; Daniels, Karen

    2011-03-01

    Acoustic techniques provide a non-invasive method of characterizing granular material properties; however, there are many challenges in formulating accurate models of sound propagation due to the inherently heterogeneous nature of granular materials. In order to quantify acoustic responses in space and time, we perform experiments in a photoelastic granular material in which the internal stress pattern (in the form of force chains) is visible. We utilize two complementary methods, high-speed imaging and piezoelectric transduction, to provide particle-scale measurements of the amplitude of the acoustic wave. We observe that the average wave amplitude is largest within particles experiencing the largest forces. The force-dependence of this amplitude is in qualitative agreement with a simple Hertzian-like model for contact area. In addition, we investigate the power spectrum of the propagating signal using the piezoelectric sensors. For a Gaussian wave packet input, we observe a broad spectrum of transmitted frequencies below the driving frequency, and we quantify the characteristic frequencies and corresponding length scales of our material as the system pressure is varied.

  12. Direct Comparison of 19F qNMR and 1H qNMR by Characterizing Atorvastatin Calcium Content

    National Research Council Canada - National Science Library

    Yang Liu; Zhaoxia Liu; Huaxin Yang; Lan He

    2016-01-01

    .... Most of the reports were based on proton qNMR (1H qNMR) and only a few fluorine qNMR (19F qNMR) were reported. No research has been conducted to directly compare the advantage and disadvantage between these two methods...

  13. Fundamentals of Shallow Water Acoustics

    CERN Document Server

    Katsnelson, Boris; Lynch, James

    2012-01-01

    Shallow water acoustics (SWA), the study of how low and medium frequency sound propagates and scatters on the continental shelves of the world's oceans, has both technical interest and a large number of practical applications. Technically, shallow water poses an interesting medium for the study of acoustic scattering, inverse theory, and propagation physics in a complicated oceanic waveguide. Practically, shallow water acoustics has interest for geophysical exploration, marine mammal studies, and naval applications. Additionally, one notes the very interdisciplinary nature of shallow water acoustics, including acoustical physics, physical oceanography, marine geology, and marine biology. In this specialized volume, the authors, all of whom have extensive at-sea experience in U.S. and Russian research efforts, have tried to summarize the main experimental, theoretical, and computational results in shallow water acoustics, with an emphasis on providing physical insight into the topics presented.

  14. Latest Trends in Acoustic Sensing

    Directory of Open Access Journals (Sweden)

    Cinzia Caliendo

    2014-03-01

    Full Text Available Acoustics-based methods offer a powerful tool for sensing applications. Acoustic sensors can be applied in many fields ranging from materials characterization, structural health monitoring, acoustic imaging, defect characterization, etc., to name just a few. A proper selection of the acoustic wave frequency over a wide spectrum that extends from infrasound (<20 Hz up to ultrasound (in the GHz–band, together with a number of different propagating modes, including bulk longitudinal and shear waves, surface waves, plate modes, etc., allow acoustic tools to be successfully applied to the characterization of gaseous, solid and liquid environments. The purpose of this special issue is to provide an overview of the research trends in acoustic wave sensing through some cases that are representative of specific applications in different sensing fields.

  15. High-Frequency Seafloor Acoustics

    CERN Document Server

    Jackson, Darrell R

    2007-01-01

    High-Frequency Seafloor Acoustics is the first book in a new series sponsored by the Office of Naval Research on the latest research in underwater acoustics. This exciting new title provides ready access to experimental data, theory, and models relevant to high-frequency seafloor acoustics and will be of interest to sonar engineers and researchers working in underwater acoustics. The physical characteristics of the seafloor affecting acoustic propagation and scattering are covered, including physical and geoacoustic properties and surface roughness. Current theories for acoustic propagation in sediments are presented along with corresponding models for reflection, scattering, and seafloor penetration. The main text is backed up by an extensive bibliography and technical appendices.

  16. A neutron-X-ray, NMR and calorimetric study of glassy Probucol synthesized using containerless techniques

    Energy Technology Data Exchange (ETDEWEB)

    Weber, J.K.R., E-mail: rweber@anl.gov [Materials Development, Inc., Arlington Heights, IL 60004 (United States); Argonne National Laboratory, Argonne, IL 60439 (United States); Benmore, C.J. [Argonne National Laboratory, Argonne, IL 60439 (United States); Department of Physics, Arizona State University, AZ 85287 (United States); Tailor, A.N.; Tumber, S.K. [Materials Development, Inc., Arlington Heights, IL 60004 (United States); Neuefeind, J. [Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Cherry, B. [Magnetic Resonance Research Center, Arizona State University, AZ 85287 (United States); Department of Chemistry and Biochemistry, Arizona State University, AZ 85287 (United States); Yarger, J.L. [Department of Physics, Arizona State University, AZ 85287 (United States); Magnetic Resonance Research Center, Arizona State University, AZ 85287 (United States); Department of Chemistry and Biochemistry, Arizona State University, AZ 85287 (United States); Mou, Q. [Magnetic Resonance Research Center, Arizona State University, AZ 85287 (United States); Department of Chemistry and Biochemistry, Arizona State University, AZ 85287 (United States); Weber, W. [Department of Physics, Arizona State University, AZ 85287 (United States); Department of Chemistry and Biochemistry, Arizona State University, AZ 85287 (United States); Byrn, S.R. [Department of Industrial and Physical Pharmacy, Purdue University, IN 47907 (United States)

    2013-10-16

    Highlights: • Acoustic levitation was used to make phase-pure glassy forms of pharmaceutical compounds. • Neutrons, X-rays and NMR were used to characterize the glasses. • The glass comprised of slightly distorted molecules packed in a random network. • Potential for new drug synthesis routes is discussed. - Abstract: Acoustic levitation was used to trap 1–3 mm diameter drops of Probucol and other pharmaceutical materials in containerless conditions. Samples were studied in situ using X-ray diffraction and ex situ using neutron diffraction, NMR and DSC techniques. The materials were brought into non-equilibrium states by supersaturating solutions or by supercooling melts. The glass transition and crystallization temperatures of glassy Probucol were 29 ± 1 and 71 ± 1 °C respectively. The glassy form was stable with a shelf life of at least 8 months. A neutron/X-ray difference function of the glass showed that while molecular sub-groups remain rigid, many of the hydrogen correlations observed in the crystal become smeared out in the disordered material. The glass is principally comprised of slightly distorted Form I Probucol molecules with disordered packing rather than large changes in the individual molecular structure. Avoiding surface contact-induced nucleation provided access to highly non-equilibrium phases and enabled synthesis of phase-pure glasses.

  17. Shallow-Water Mud Acoustics

    Science.gov (United States)

    2015-09-30

    1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Shallow-Water Mud Acoustics William L. Siegmann...models and methods that explain observed material and acoustic properties of different physical types of shallow-ocean mud sediments. Other goals...are to assess prior data relating to the acoustic properties of mud and to provide guidance in the development and interpretation of experiments. A

  18. NDE Acoustic Microscopy Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose is to develop advanced, more effective high-resolution micro-NDE materials characterization methods using scanning acoustic microscopy. The laboratory's...

  19. Acoustic Communications Measurement Systems (ACOMMS)

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Design and develop adaptive signal processing techniques to improve underwater acoustic communications and networking. Phase coherent and incoherent signal...

  20. Combined Environment Acoustic Chamber (CEAC)

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The CEAC imposes combined acoustic, thermal and mechanical loads on aerospace structures. The CEAC is employed to measure structural response and determine...

  1. Use of NMR and NMR Prediction Software to Identify Components in Red Bull Energy Drinks

    Science.gov (United States)

    Simpson, Andre J.; Shirzadi, Azadeh; Burrow, Timothy E.; Dicks, Andrew P.; Lefebvre, Brent; Corrin, Tricia

    2009-01-01

    A laboratory experiment designed as part of an upper-level undergraduate analytical chemistry course is described. Students investigate two popular soft drinks (Red Bull Energy Drink and sugar-free Red Bull Energy Drink) by NMR spectroscopy. With assistance of modern NMR prediction software they identify and quantify major components in each…

  2. NMR Spectra through the Eyes of a Student: Eye Tracking Applied to NMR Items

    Science.gov (United States)

    Topczewski, Joseph J.; Topczewski, Anna M.; Tang, Hui; Kendhammer, Lisa K.; Pienta, Norbert J.

    2017-01-01

    Nuclear magnetic resonance spectroscopy (NMR) plays a key role in introductory organic chemistry, spanning theory, concepts, and experimentation. Therefore, it is imperative that the instruction methods for NMR are both efficient and effective. By utilizing eye tracking equipment, the researchers were able to monitor how second-semester organic…

  3. Performance of the WeNMR CS-Rosetta3 web server in CASD-NMR.

    Science.gov (United States)

    van der Schot, Gijs; Bonvin, Alexandre M J J

    2015-08-01

    We present here the performance of the WeNMR CS-Rosetta3 web server in CASD-NMR, the critical assessment of automated structure determination by NMR. The CS-Rosetta server uses only chemical shifts for structure prediction, in combination, when available, with a post-scoring procedure based on unassigned NOE lists (Huang et al. in J Am Chem Soc 127:1665-1674, 2005b, doi: 10.1021/ja047109h). We compare the original submissions using a previous version of the server based on Rosetta version 2.6 with recalculated targets using the new R3FP fragment picker for fragment selection and implementing a new annotation of prediction reliability (van der Schot et al. in J Biomol NMR 57:27-35, 2013, doi: 10.1007/s10858-013-9762-6), both implemented in the CS-Rosetta3 WeNMR server. In this second round of CASD-NMR, the WeNMR CS-Rosetta server has demonstrated a much better performance than in the first round since only converged targets were submitted. Further, recalculation of all CASD-NMR targets using the new version of the server demonstrates that our new annotation of prediction quality is giving reliable results. Predictions annotated as weak are often found to provide useful models, but only for a fraction of the sequence, and should therefore only be used with caution.

  4. Continuous Flow 1H and 13C NMR Spectroscopy in Microfluidic Stripline NMR Chips

    NARCIS (Netherlands)

    Oosthoek-de Vries, Anna Jo; Bart, Jacob; Tiggelaar, Roald M.; Janssen, Johannes W.G.; van Bentum, Jan (P.J.M.); Gardeniers, Han J.G.E.; Kentgens, Arno P.M.

    2017-01-01

    Microfluidic stripline NMR technology not only allows for NMR experiments to be performed on small sample volumes in the submicroliter range, but also experiments can easily be performed in continuous flow because of the stripline's favorable geometry. In this study we demonstrate the possibility of

  5. Crystallographic and dynamic aspects of solid-state NMR calibration compounds: towards ab initio NMR crystallography

    DEFF Research Database (Denmark)

    Li, Xiaozhou; Tapmeyer, Lukas; Bolte, Michael

    2016-01-01

    The excellent results of dispersion-corrected density functional theory (DFT-D) calculations for static systems have been well established over the past decade. The introduction of dynamics into DFT-D calculations is a target, especially for the field of molecular NMR crystallography. Four 13C ss-NMR...

  6. Acoustic transparency and slow sound using detuned acoustic resonators

    DEFF Research Database (Denmark)

    Santillan, Arturo Orozco; Bozhevolnyi, Sergey I.

    2011-01-01

    We demonstrate that the phenomenon of acoustic transparency and slowsound propagation can be realized with detuned acoustic resonators (DAR), mimicking thereby the effect of electromagnetically induced transparency (EIT) in atomic physics. Sound propagation in a pipe with a series of side...

  7. Ares I Scale Model Acoustic Test Lift-Off Acoustics

    Science.gov (United States)

    Counter, Douglas D.; Houston, Janie D.

    2011-01-01

    The lift-off acoustic (LOA) environment is an important design factor for any launch vehicle. For the Ares I vehicle, the LOA environments were derived by scaling flight data from other launch vehicles. The Ares I LOA predicted environments are compared to the Ares I Scale Model Acoustic Test (ASMAT) preliminary results.

  8. NMR methodologies in the analysis of blueberries.

    Science.gov (United States)

    Capitani, Donatella; Sobolev, Anatoly P; Delfini, Maurizio; Vista, Silvia; Antiochia, Riccarda; Proietti, Noemi; Bubici, Salvatore; Ferrante, Gianni; Carradori, Simone; De Salvador, Flavio Roberto; Mannina, Luisa

    2014-06-01

    An NMR analytical protocol based on complementary high and low field measurements is proposed for blueberry characterization. Untargeted NMR metabolite profiling of blueberries aqueous and organic extracts as well as targeted NMR analysis focused on anthocyanins and other phenols are reported. Bligh-Dyer and microwave-assisted extractions were carried out and compared showing a better recovery of lipidic fraction in the case of microwave procedure. Water-soluble metabolites belonging to different classes such as sugars, amino acids, organic acids, and phenolic compounds, as well as metabolites soluble in organic solvent such as triglycerides, sterols, and fatty acids, were identified. Five anthocyanins (malvidin-3-glucoside, malvidin-3-galactoside, delphinidin-3-glucoside, delphinidin-3-galactoside, and petunidin-3-glucoside) and 3-O-α-l-rhamnopyranosyl quercetin were identified in solid phase extract. The water status of fresh and withered blueberries was monitored by portable NMR and fast-field cycling NMR. (1) H depth profiles, T2 transverse relaxation times and dispersion profiles were found to be sensitive to the withering. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. From Architectural Acoustics to Acoustical Architecture Using Computer Simulation

    DEFF Research Database (Denmark)

    Schmidt, Anne Marie Due; Kirkegaard, Poul Henning

    2005-01-01

    to the design of Bagsvaerd Church by Jørn Utzon. The paper discusses the advantages and disadvantages of the programme in each phase compared to the works of architects not using acoustic simulation programmes. The conclusion of the paper points towards the need to apply the acoustic simulation programmes...... properties prior to the actual construction of a building. With the right tools applied, acoustic design can become an integral part of the architectural design process. The aim of this paper is to investigate the field of application that an acoustic simulation programme can have during an architectural...... acoustic design process and to set up a strategy to develop future programmes. The emphasis is put on the first three out of four phases in the working process of the architect and a case study is carried out in which each phase is represented by typical results ? as exemplified with reference...

  10. Acoustic Mechanical Feedthroughs

    Science.gov (United States)

    Sherrit, Stewart; Walkemeyer, Phillip; Bao, Xiaoqi; Bar-Cohen, Yoseph; Badescu, Mircea

    2013-01-01

    Electromagnetic motors can have problems when operating in extreme environments. In addition, if one needs to do mechanical work outside a structure, electrical feedthroughs are required to transport the electric power to drive the motor. In this paper, we present designs for driving rotary and linear motors by pumping stress waves across a structure or barrier. We accomplish this by designing a piezoelectric actuator on one side of the structure and a resonance structure that is matched to the piezoelectric resonance of the actuator on the other side. Typically, piezoelectric motors can be designed with high torques and lower speeds without the need for gears. One can also use other actuation materials such as electrostrictive, or magnetostrictive materials in a benign environment and transmit the power in acoustic form as a stress wave and actuate mechanisms that are external to the benign environment. This technology removes the need to perforate a structure and allows work to be done directly on the other side of a structure without the use of electrical feedthroughs, which can weaken the structure, pipe, or vessel. Acoustic energy is pumped as a stress wave at a set frequency or range of frequencies to produce rotary or linear motion in a structure. This method of transferring useful mechanical work across solid barriers by pumping acoustic energy through a resonant structure features the ability to transfer work (rotary or linear motion) across pressure or thermal barriers, or in a sterile environment, without generating contaminants. Reflectors in the wall of barriers can be designed to enhance the efficiency of the energy/power transmission. The method features the ability to produce a bi-directional driving mechanism using higher-mode resonances. There are a variety of applications where the presence of a motor is complicated by thermal or chemical environments that would be hostile to the motor components and reduce life and, in some instances, not be

  11. Frequency steerable acoustic transducers

    Science.gov (United States)

    Senesi, Matteo

    Structural health monitoring (SHM) is an active research area devoted to the assessment of the structural integrity of critical components of aerospace, civil and mechanical systems. Guided wave methods have been proposed for SHM of plate-like structures using permanently attached piezoelectric transducers, which generate and sense waves to evaluate the presence of damage. Effective interrogation of structural health is often facilitated by sensors and actuators with the ability to perform electronic, i.e. phased array, scanning. The objective of this research is to design an innovative directional piezoelectric transducer to be employed for the localization of broadband acoustic events, or for the generation of Lamb waves for active interrogation of structural health. The proposed Frequency Steerable Acoustic Transducers (FSATs) are characterized by a spatial arrangement of active material which leads to directional characteristics varying with frequency. Thus FSATs can be employed both for directional sensing and generation of guided waves without relying on phasing and control of a large number of channels. The analytical expression of the shape of the FSATs is obtained through a theoretical formulation for continuously distributed active material as part of a shaped piezoelectric device. The FSAT configurations analyzed in this work are a quadrilateral array and a geometry which corresponds to a spiral in the wavenumber domain. The quadrilateral array is experimentally validated, confirming the concept of frequency-dependent directionality. Its limited directivity is improved by the Wavenumber Spiral FSAT (WS-FSAT), which, instead, is characterized by a continuous frequency dependent directionality. Preliminary validations of the WS-FSAT, using a laser doppler vibrometer, are followed by the implementation of the WS-FSAT as a properly shaped piezo transducer. The prototype is first used for localization of acoustic broadband sources. Signal processing

  12. Acoustic Model Testing Chronology

    Science.gov (United States)

    Nesman, Tom

    2017-01-01

    Scale models have been used for decades to replicate liftoff environments and in particular acoustics for launch vehicles. It is assumed, and analyses supports, that the key characteristics of noise generation, propagation, and measurement can be scaled. Over time significant insight was gained not just towards understanding the effects of thruster details, pad geometry, and sound mitigation but also to the physical processes involved. An overview of a selected set of scale model tests are compiled here to illustrate the variety of configurations that have been tested and the fundamental knowledge gained. The selected scale model tests are presented chronologically.

  13. Acoustic Properties of Cellulose

    Science.gov (United States)

    Trematerra, Amelia; Lombardi, Ilaria

    2017-08-01

    Cellulose is the oldest material for thermal insulation in construction field. Thomas Jefferson was the first architect that used the cellulose in his project of the Monticello house (1800). But only after 1945 that the cellulose from newsprint was used across America and northern Europe. In the 70s with the energy crisis it Austria, Czech Republic, Switzerland and Germany began the production of cellulose derived from paper newspapers. It used for both winter and summer thermal insulation, while respecting the environment. In this paper are reported acoustic measurements carried out with the tube of Kundt, with the cellulose melted and with glue with different thicknesses.

  14. Coffee roasting acoustics.

    Science.gov (United States)

    Wilson, Preston S

    2014-06-01

    Cracking sounds emitted by coffee beans during the roasting process were recorded and analyzed to investigate the potential of using the sounds as the basis for an automated roast monitoring technique. Three parameters were found that could be exploited. Near the end of the roasting process, sounds known as "first crack" exhibit a higher acoustic amplitude than sounds emitted later, known as "second crack." First crack emits more low frequency energy than second crack. Finally, the rate of cracks appearing in the second crack chorus is higher than the rate in the first crack chorus.

  15. Taming Acoustic Cavitation

    CERN Document Server

    Rivas, David Fernandez; Enriquez, Oscar R; Versluis, Michel; Prosperetti, Andrea; Gardeniers, Han; Lohse, Detlef

    2012-01-01

    In this fluid dynamics video we show acoustic cavitation occurring from pits etched on a silicon surface. By immersing the surface in a liquid, gas pockets are entrapped in the pits which upon ultrasonic insonation, are observed to shed cavitation bubbles. Modulating the driving pressure it is possible to induce different behaviours based on the force balance that determines the interaction among bubbles and the silicon surface. This system can be used for several applications like sonochemical water treatment, cleaning of surfaces with deposited materials such as biofilms.

  16. Studying materials using acoustic waves

    Science.gov (United States)

    Apfel, R. E.

    1988-03-01

    This final report summarizes the activity of the contractor in meeting the objectives of the contract. A comprehensive bibliography and list of participants on the contract work are included along with a discussion including: microcavitation, microparticle characterization, interfacial characterization using acoustic levitation, measurements of the acoustic nonlinear parameter for determining the composition of mixtures.

  17. Propagation of Ion Acoustic Perturbations

    DEFF Research Database (Denmark)

    Pécseli, Hans

    1975-01-01

    Equations describing the propagation of ion acoustic perturbations are considered, using the assumption that the electrons are Boltzman distributed and isothermal at all times. Quasi-neutrality is also considered.......Equations describing the propagation of ion acoustic perturbations are considered, using the assumption that the electrons are Boltzman distributed and isothermal at all times. Quasi-neutrality is also considered....

  18. Acoustic Center or Time Origin?

    DEFF Research Database (Denmark)

    Staffeldt, Henrik

    1999-01-01

    The paper discusses the acoustic center in relation to measurements of loudspeaker polar data. Also, it presents the related concept time origin and discusses the deviation that appears between positions of the acoustic center found by wavefront based and time based measuring methods....

  19. Giving acoustics a fairer hearing.

    Science.gov (United States)

    Marriott, Ken

    2012-05-01

    Ken Marriott, an independent acoustics consultant with Industrial Commercial & Technical Consultants (ICTC), outlines some of the key acoustics considerations for those planning new hospital build or refurbishment schemes, cautioning that, all too often, this important area is not properly considered at a sufficiently early project stage.

  20. Nonlinear Acoustic Characterization of Targets

    Science.gov (United States)

    2008-01-01

    lack of advanced measurement equipment such as piezoelectric microphones and transducers, nonlinear ul- trasonic acoustics has mostly remained a...the poor coupling between solids and air, and could be more easily measured with equipment such as a Laser Doppler Vibrometer (LDV). Acoustic

  1. Flow NMR of polymers in external fields

    Energy Technology Data Exchange (ETDEWEB)

    Boehme, Ute; Bagusat, Frank; Scheler, Ulrich [Leibniz Institute of Polymer Research Dresden (Germany)

    2008-07-01

    Pulsed-field gradient NMR is applied to study the motion of polymers in an external electric field and under mechanical shear. The application of an electric field drives motion of charged species. In conjunction with the diffusion coefficient from the electrophoretic mobility the effective charge per molecule is derived. The electric field applicable in the aqueous system is too weak to deform the polymer or even abstract counterions. In a shear flow established in a Couette cell partial orientation of polymer chains is measured via residual dipolar couplings. The entire flow field in a non-symmetric flow cell is monitored by a combination of PFG NMR and NMR imaging exhibiting regions of high shear and locally low shear, where polymers relax.

  2. Characterization by NMR of ozonized methyl linoleate

    Energy Technology Data Exchange (ETDEWEB)

    Diaz, Maritza F. [National Center for Scientific Research, Havana (Cuba). Ozone Research Center. Dept. of Ozonized Substances]. E-mail: maritza.diaz@cnic.edu.cu; Gavin, Jose A. [University of the Laguna, Tenerife (Spain)

    2007-07-01

    In the present study ozonized methyl linoleate with peroxide index of 1,800 mmol-equiv kg{sup -1} was chemically characterized. Ozonation of methyl linoleate produced hydroperoxides, ozonides and aldehydes which were identified by {sup 1}H and {sup 13}C NMR two-dimensional. The standard methyl linoleate and ozonized methyl linoleate shown very similar {sup 1}H NMR spectra except for the signals at {delta} 9.7 and {delta} 9.6 that correspond to aldehydic hydrogen, {delta} 5.7 and {delta} 5.5 (olefinic signals from hydroperoxides) and {delta} 5.2 ppm (multiplet from ozonides methynic hydrogen). Other resonance assignments are based on the connectivities provided by the hydrogen scalar coupling constants. These results indicate that NMR spectroscopy can provide valuable information about the amount of formed oxygenated compounds in the ozonized methyl linoleate in order to use it to follow up ozone therapy and chemistry of ozonized vegetable oil. (author)

  3. NMR metabolomics of renal cancer: an overview.

    Science.gov (United States)

    Gil, Ana M; de Pinho, Paula Guedes; Monteiro, Márcia S; Duarte, Iola F

    2015-09-23

    This paper reviews the use of NMR metabolomics for the metabolic characterization of renal cancer. The existing challenges in the clinical management of this disease are first presented, followed by a brief introduction to the metabolomics approach, in the context of cancer research. A subsequent review of the literature on NMR metabolic studies of renal cancer reveals that the subject has been clearly underdeveloped, compared with other types of cancer, particularly regarding cultured cells and tissue analysis. NMR analysis of biofluids has focused on blood (plasma or serum) metabolomics, comprising no account of studies on human urine, in spite of its noninvasiveness and physiological proximity to the affected organs. Finally, some areas of potential future development are identified.

  4. The eNMR platform for structural biology

    OpenAIRE

    Bonvin, Alexandre M. J. J.; Rosato, Antonio; Wassenaar, Tsjerk A.

    2010-01-01

    The e-NMR project is a European cooperation initiative that aims at providing the bio-NMR user community with a software platform integrating and streamlining the computational approaches necessary for the analysis of bio-NMR data. The e-NMR platform is based on a Grid computational infrastructure. A main focus of the current implementation of the e-NMR platform is on streamlining structure determination protocols. Indeed, to facilitate the use of NMR spectroscopy in the life sciences, the eN...

  5. Wastewater treatment with acoustic separator

    Science.gov (United States)

    Kambayashi, Takuya; Saeki, Tomonori; Buchanan, Ian

    2017-07-01

    Acoustic separation is a filter-free wastewater treatment method based on the forces generated in ultrasonic standing waves. In this report, a batch-system separator based on acoustic separation was demonstrated using a small-scale prototype acoustic separator to remove suspended solids from oil sand process-affected water (OSPW). By applying an acoustic separator to the batch use OSPW treatment, the required settling time, which was the time that the chemical oxygen demand (COD) decreased to the environmental criterion (<200 mg/L), could be shortened from 10 to 1 min. Moreover, for a 10 min settling time, the acoustic separator could reduce the FeCl3 dose as coagulant in OSPW treatment from 500 to 160 mg/L.

  6. Review of Progress in Acoustic Levitation

    Science.gov (United States)

    Andrade, Marco A. B.; Pérez, Nicolás; Adamowski, Julio C.

    2017-12-01

    Acoustic levitation uses acoustic radiation forces to counteract gravity and suspend objects in mid-air. Although acoustic levitation was first demonstrated almost a century ago, for a long time, it was limited to objects much smaller than the acoustic wavelength levitating at fixed positions in space. Recent advances in acoustic levitation now allow not only suspending but also rotating and translating objects in three dimensions. Acoustic levitation is also no longer restricted to small objects and can now be employed to levitate objects larger than the acoustic wavelength. This article reviews the progress of acoustic levitation, focusing on the working mechanism of different types of acoustic levitation devices developed to date. We start with a brief review of the theory. Then, we review the acoustic levitation methods to suspend objects at fixed positions, followed by the techniques that allow the manipulation of objects. Finally, we present a brief summary and offer some future perspectives for acoustic levitation.

  7. Acoustics and Hearing

    CERN Document Server

    Damaske, Peter

    2008-01-01

    When one listens to music at home, one would like to have an acoustic impression close to that of being in the concert hall. Until recently this meant elaborate multi-channelled sound systems with 5 or more speakers. But head-related stereophony achieves the surround-sound effect in living rooms with only two loudspeakers. By virtue of their slight directivity as well as an electronic filter the limitations previously common to two-speaker systems can be overcome and this holds for any arbitrary two-channel recording. The book also investigates the question of how a wide and diffuse sound image can arise in concert halls and shows that the quality of concert halls decisively depends on diffuse sound images arising in the onset of reverberation. For this purpose a strong onset of reverberation is modified in an anechoic chamber by electroacoustic means. Acoustics and Hearing proposes ideas concerning signal processing in the auditory system that explain the measured results and the resultant sound effects plea...

  8. Acoustic shock injury (ASI).

    Science.gov (United States)

    Westcott, Myriam

    2006-12-01

    The potential severity and persistence of ASI symptoms has significant clinical and medico-legal implications. With the rapid growth of call centres around the world, professionals providing tinnitus and hyperacusis therapy are increasingly likely to encounter some or all of the cluster of ASI symptoms in their clients. Acoustic shock injury (ASI), occurring as a result of exposure to a sudden unexpected loud sound, has been observed to cause a specific and consistent pattern of neurophysiological and psychological symptoms. These include aural pain, tinnitus, hyperacusis/phonophobia, vertigo and other unusual symptoms such as numbness or burning sensations around the ear. A range of emotional reactions including trauma, anxiety and depression can develop. Call centre staff using a telephone headset or handset are vulnerable to ASI because of the increased likelihood of exposure, close to their ear(s), of sudden unexpected loud sounds randomly transmitted via the telephone line. This paper presents an overview of a study of 103 people exposed to 123 acoustic incidents, and of the proposed neurophysiological mechanism of ASI, in particular tonic tensor tympani syndrome (TTTS). An understanding of TTTS has the potential to provide insight into the neurophysiological and psychological development of tinnitus and hyperacusis and the association with high levels of emotional trauma and anxiety. ASI rehabilitation is discussed.

  9. New Designs for NMR Core Scanning

    Science.gov (United States)

    Bluemich, B.; Anferova, S.; Talnishnikh, E.; Arnold, J.; Clauser, C.

    2006-12-01

    Within the last ten years, mobile magnetic resonance has moved from the oil field to many new areas of application. While the focus of mobile NMR in the past was on single-sided or inside-out NMR, the advent of tube-shaped Halbach magnets has introduced the conventional outside-in NMR concept to mobile NMR where the object is inside a magnet. Our Halbach magnet is constructed from small magnet blocks at light weight and low cost with a magnetic field sufficiently homogeneous. To automatize NMR measurements, the Halbach magnet is mounted on a sliding table to scan long core sections without human interaction. In homogeneous magnetic fields, the longitudinal relaxation time T1 and even the transverse relaxation time T2 are proportional to the pore diameters of rocks. Hence, the T1 and T2 signals map the pore-size distribution of the studied rock cores. For fully saturated samples the integral of the distribution curve is proportional to porosity. The porosity values from NMR measurements with the Halbach magnet are used to estimate permability. The Halbach magnet can be used for certain sample geometries in combination with exchangeable radio frequency (rf) coils with different diameters from 24 mm up to 80 mm. To measure standard Ocean Drilling Program (ODP)/Integrated Ocean Drilling Program (IODP) cores, which have a standard diameter of 60 mm and are split lengthwise after recovery, we use a surface figure-8 rf coil with an inner diameter of 60 mm. Besides 1D T2 measurements, we perform relaxation-relaxation correlation experiments, where T1 and T2 are measured in parallel. In this way, the influence of diffusion on the shape of the T2 distribution function is probed. A gradient coil system was designed to perform Pulsed Field Gradients (PFG) experiments. As the gradient coils restrict the axial access to the magnet, only cylindrical core plugs with 20 mm in diameter can be analysed by PFG NMR methods. The homogeneity of the magnetic field in the sensitive volume

  10. Direct Comparison of 19F qNMR and 1H qNMR by Characterizing Atorvastatin Calcium Content

    OpenAIRE

    Yang Liu; Zhaoxia Liu; Huaxin Yang; Lan He

    2016-01-01

    Quantitative nuclear magnetic resonance (qNMR) is a powerful tool in measuring drug content because of its high speed, sensitivity, and precision. Most of the reports were based on proton qNMR (1H qNMR) and only a few fluorine qNMR (19F qNMR) were reported. No research has been conducted to directly compare the advantage and disadvantage between these two methods. In the present study, both 19F and 1H qNMR were performed to characterize the content of atorvastatin calcium with the same intern...

  11. A slim-line NMR logging tool to measure moisture in soils

    Science.gov (United States)

    Sucre, Oscar; Andreas, Pohlmeier; Bernhard, Blümich

    2010-05-01

    The transport of water in soils is a physical phenomenon of importance in soil science and climatology. This work reports progress in the development of slim-line NMR logging tool ('the sensor') to characterize soil moisture, developed within the DFG-funded interdisciplinary collaborative project TR32. To demonstrate the capability of the NMR technique to follow the drying process of water in soils, several moisture measurements were performed with the sensor on two different types of model soils (sand FH31 and a mix of sand FH31/ silt W3) during an one-step outflow experiment. The soils were packed in columns approximately one meter high. The sensor could be raised and lowered inside a plastic tube (2 mm thick) in the soil column similar to a wire-line logging tool. Working at a frequency of 12 MHz, the sensitive volume lies 6 mm away from the outer sensor surface, measuring the NMR signal of proton spins lying 4 mm inside the soil. Using the direct proportionality between the amplitude of the NMR signal and the water content, partial saturation profiles before, during and after outflow can be obtained. By comparing the data to numerical solutions by means of HYDRUS 1D, we the hydraulic parameters Ks, α, n and l of the Mualem - Van Genuchten model can be assessed for the model soils under study. Furthermore, technical advances to make this tool sturdier for outdoor field measurements and to increase the signal sensitivity are discussed. They include a reduction of the echo time by damping the magneto-acoustic oscillations and the use of the gradiometer coils to make the sensor less sensitive to far-field noise. The performance of the sensor with different coils and under different shielding principles is evaluated to find the optimum design and operating conditions. First field measurements of the sensor from the Selhausen test site are presented.

  12. EXPERIMENTAL AND THEORETICAL NMR STUDY OF 4-(1 ...

    African Journals Online (AJOL)

    Preferred Customer

    experimental and theoretical data have showed that the molecular geometry and the ... 1D and 2D hetero- and homonuclear NMR methods enable to ... The essence of this study is briefly to report experimental and theoretical NMR features of.

  13. nmrML: a community supported open data standard for the description, storage, and exchange of NMR data.

    Science.gov (United States)

    Schober, Daniel; Jacob, Daniel; Wilson, Michael; Cruz, Joseph A; Marcu, Ana; Grant, Jason R; Moing, Annick; Deborde, Catherine; de Figueiredo, Luis F; Haug, Kenneth; Rocca-Serra, Philippe; Easton, John M; Ebbels, Timothy M D; Hao, Jie; Ludwig, Christian; Günther, Ulrich L; Rosato, Antonio; Klein, Matthias S; Lewis, Ian; Luchinat, Claudio; Jones, Andrew R; Grauslys, Arturas; Larralde, Martin; Yokochi, Masashi; Kobayashi, Naohiro; Porzel, Andrea; Griffin, Julian; Viant, Mark R; Wishart, David S; Steinbeck, Christoph; Salek, Reza M; Neumann, Steffen

    2017-10-16

    NMR is a widely used analytical technique with a growing number of repositories available. As a result, demands for a vendor-agnostic, open data format for long-term archiving of NMR data have emerged with the aim to ease and encourage sharing, comparison and reuse of NMR data. Here we present nmrML, an open XML-based exchange and storage format for NMR spectral data. The nmrML format is intended to be fully compatible with existing NMR data for chemical, biochemical and metabolomics experiments. nmrML can capture raw NMR data, spectral data acquisition parameters and, where available, spectral metadata such as chemical structures associated with spectral assignments. The nmrML format is compatible with pure-compound NMR data for reference spectral libraries as well as NMR data from complex bio-mixtures i.e. metabolomics experiments. To facilitate format conversions, we provide nmrML converters for Bruker and Agilent/Varian vendor formats. In addition, easy-to-use web-based spectral viewing, processing and spectral assignment tools that read and write nmrML have been developed. Software libraries and web services for data validation are available for tool developers and end-users. The nmrML format has already been adopted for capturing and disseminating NMR data for small molecules by several open source data processing tools and metabolomics reference spectral libraries, e.g. serving as storage format for the MetaboLights data repository. The nmrML open access data standard has been endorsed by the Metabolomics Standards Initiative (MSI) and we here encourage user participation and feedback to increase usability and make it a successful standard.

  14. Coupled Acoustic-Mechanical Bandgaps

    DEFF Research Database (Denmark)

    Jensen, Jakob Søndergaard; Kook, Junghwan

    2016-01-01

    In this work, we study the existence of coupled bandgaps for corrugated plate structures and acoustic channels. The study is motivated by the observation that the performance of traditional bandgap structures, such as periodic plates, may be compromised due to the coupling to a surrounding acoust...... domains into account. Additionally, the coupling is shown to introduce extra gaps in the band structure due to modal interaction and the appearance of a cut-on frequency for the fundamental acoustic mode.......In this work, we study the existence of coupled bandgaps for corrugated plate structures and acoustic channels. The study is motivated by the observation that the performance of traditional bandgap structures, such as periodic plates, may be compromised due to the coupling to a surrounding acoustic...... medium and the presence of acoustic resonances. It is demonstrated that corrugation of the plate structure can introduce bending wave bandgaps and bandgaps in the acoustic domain in overlapping and audible frequency ranges. This effect is preserved also when taking the physical coupling between the two...

  15. PORTABLE ACOUSTIC MONITORING PACKAGE (PAMP)

    Energy Technology Data Exchange (ETDEWEB)

    John L. Loth; Gary J. Morris; George M. Palmer; Richard Guiler; Patrick Browning

    2004-07-20

    The Portable Acoustic Monitoring Package (PAMP) has been designed to record and monitor the acoustic signal in natural gas transmission lines. In particular the three acoustic signals associated with a line leak. The system is portable ({approx}30 lbs) and is designed for line pressures up to 1000 psi. It has become apparent that cataloging of the various background acoustic signals in natural gas transmission line is very important if a system to identify leak signals is to be developed. The low-pressure (0-200 psig) laboratory test phase has been completed and a number of field trials have been conducted. Before the cataloging phase could begin, a few problems identified in field trials identified had to be corrected such as: (1) Decreased microphone sensitivity at line pressures above 250 psig. (2) The inability to deal with large data sets collected when cataloging the variety of signals in a transmission line. (3) The lack of an available online acoustic calibration system. These problems have been solved and the WVU PAMP is now fully functional over the entire pressure range found in the Natural Gas transmission lines in this region. Field portability and reliability have been greatly improved. Data collection and storage have also improved to the point were the full acoustic spectrum of acoustic signals can be accurately cataloged, recorded and described.

  16. Controlling sound with acoustic metamaterials

    Science.gov (United States)

    Cummer, Steven A.; Christensen, Johan; Alù, Andrea

    2016-03-01

    Acoustic metamaterials can manipulate and control sound waves in ways that are not possible in conventional materials. Metamaterials with zero, or even negative, refractive index for sound offer new possibilities for acoustic imaging and for the control of sound at subwavelength scales. The combination of transformation acoustics theory and highly anisotropic acoustic metamaterials enables precise control over the deformation of sound fields, which can be used, for example, to hide or cloak objects from incident acoustic energy. Active acoustic metamaterials use external control to create effective material properties that are not possible with passive structures and have led to the development of dynamically reconfigurable, loss-compensating and parity-time-symmetric materials for sound manipulation. Challenges remain, including the development of efficient techniques for fabricating large-scale metamaterial structures and converting laboratory experiments into useful devices. In this Review, we outline the designs and properties of materials with unusual acoustic parameters (for example, negative refractive index), discuss examples of extreme manipulation of sound and, finally, provide an overview of future directions in the field.

  17. Hyperpolarized NMR Probes for Biological Assays

    Directory of Open Access Journals (Sweden)

    Sebastian Meier

    2014-01-01

    Full Text Available During the last decade, the development of nuclear spin polarization enhanced (hyperpolarized molecular probes has opened up new opportunities for studying the inner workings of living cells in real time. The hyperpolarized probes are produced ex situ, introduced into biological systems and detected with high sensitivity and contrast against background signals using high resolution NMR spectroscopy. A variety of natural, derivatized and designed hyperpolarized probes has emerged for diverse biological studies including assays of intracellular reaction progression, pathway kinetics, probe uptake and export, pH, redox state, reactive oxygen species, ion concentrations, drug efficacy or oncogenic signaling. These probes are readily used directly under natural conditions in biofluids and are often directly developed and optimized for cellular assays, thus leaving little doubt about their specificity and utility under biologically relevant conditions. Hyperpolarized molecular probes for biological NMR spectroscopy enable the unbiased detection of complex processes by virtue of the high spectral resolution, structural specificity and quantifiability of NMR signals. Here, we provide a survey of strategies used for the selection, design and use of hyperpolarized NMR probes in biological assays, and describe current limitations and developments.

  18. Synthesis and NMR Elucidation of Novel Pentacycloundecane ...

    African Journals Online (AJOL)

    NICO

    2012-01-24

    Jan 24, 2012 ... Herein we report the synthesis and NMR elucidation of five novel pentacycloundecane (PCU)-derived short peptides as potential. HIV protease inhibitors. 1H and 13C spectral analysis show major overlapping of methine resonance of the PCU 'cage' thereby making it extremely difficult to assign the NMR ...

  19. Developments in Solid-State NMR

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 11. Developments in Solid-State NMR. K V Ramanathan. General Article Volume 20 Issue 11 November 2015 pp 1040-1052. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/020/11/1040-1052 ...

  20. Bench-top NMR-food

    NARCIS (Netherlands)

    Voda, M.A.; Duynhoven, Van J.

    2016-01-01

    In food research and development, relaxometric and diffusometric benchtop NMR methods have been used to obtain quantitative phase compositional and food microstructural parameters in a routine manner. The most commonly used applications are assessment of solid fat content, and water and oil

  1. NMR Analysis of Some Pentacycloundecanedione Derivatives

    African Journals Online (AJOL)

    NJD

    In the proton NMR spectrum the methylene protons are registered as an AB spin system at 2.03 and 1.89 ppm. A relatively complex pattern between 2.68 and 3.15 ppm, which integrates to eight protons represents the eight methine protons. The signals of the geminal PCU bridge methylene protons. (H-4) are registered as ...

  2. Quantification of complex mixtures by NMR

    NARCIS (Netherlands)

    Duynhoven, van J.P.M.; Velzen, van E.; Jacobs, D.M.

    2013-01-01

    NMR has firmly established itself as an analytical tool that can quantify analyte concentrations in complex mixtures in a rapid, cost-effective, accurate and precise manner. Here, the technological advances with respect to instrumentation, sample preparation, data acquisition and data processing

  3. Structures of Biomolecules by NMR Spectroscopy

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 11. Structures of Biomolecules by NMR Spectroscopy. Hanudatta S Atreya. General Article Volume 20 Issue 11 November 2015 pp 1033-1039. Fulltext. Click here to view fulltext PDF. Permanent link:

  4. Solid-state NMR for bacterial biofilms

    Science.gov (United States)

    Reichhardt, Courtney; Cegelski, Lynette

    2014-04-01

    Bacteria associate with surfaces and one another by elaborating an extracellular matrix to encapsulate cells, creating communities termed biofilms. Biofilms are beneficial in some ecological niches, but also contribute to the pathogenesis of serious and chronic infectious diseases. New approaches and quantitative measurements are needed to define the composition and architecture of bacterial biofilms to help drive the development of strategies to interfere with biofilm assembly. Solid-state nuclear magnetic resonance (NMR) is uniquely suited to the examination of insoluble and complex macromolecular and whole-cell systems. This article highlights three examples that implement solid-state NMR to deliver insights into bacterial biofilm composition and changes in cell-wall composition as cells transition to the biofilm lifestyle. Most recently, solid-state NMR measurements provided a total accounting of the protein and polysaccharide components in the extracellular matrix of an Escherichia coli biofilm and transformed our qualitative descriptions of matrix composition into chemical parameters that permit quantitative comparisons among samples. We present additional data for whole biofilm samples (cells plus the extracellular matrix) that complement matrix-only analyses. The study of bacterial biofilms by solid-state NMR is an exciting avenue ripe with many opportunities and we close the article by articulating some outstanding questions and future directions in this area.

  5. NMR and mushrooms : imaging post harvest senescence

    NARCIS (Netherlands)

    Donker, H.C.W.

    1999-01-01

    The objective of the study described in this thesis was to explore the potentials of NMR for the study of water relations in harvested mushrooms ( Agaricus bisporus ). Since harvested mushrooms tend to continue their growth after harvest, their morphogenesis is heavily

  6. NMR characterization of polymers: Review and update

    Science.gov (United States)

    NMR spectroscopy is a major technique for the characterization and analysis of polymers. A large number of methodologies have been developed in both the liquid and the solid state, and the literature has grown considerably (1-5). The field now covers a broad spectrum of activities, including polym...

  7. Theoretical molecular structure, vibrational frequencies and NMR ...

    African Journals Online (AJOL)

    Theoretical results have been successfully compared with available experimental data in the literature. Regarding the calculations, 2mpe-4bb prefers enol-imine form and DFT method is superior to HF approach except for predicting bond lengths. KEY WORDS: Schiff bases, Normal mode frequencies, HF, DFT, NMR. Bull.

  8. NMR Analysis of Some Pentacycloundecanedione Derivatives

    African Journals Online (AJOL)

    NJD

    The complete NMR elucidation of four pentacycloundecanedione (PCUdione) derivatives is described. Major proton shifts occur when additions are performed on the carbonyl carbons. Some of the carbon signals are also transposed. Despite the fact that the signals of the methine protons on the cage skeleton experience ...

  9. AB INITIO STUDY, INVESTIGATION OF NMR SHIELDING ...

    African Journals Online (AJOL)

    Preferred Customer

    Ab initio study, investigation of NMR shielding tensors, NBO and vibrational frequency. Bull. Chem. Soc. Ethiop. 2010, 24(2). 231. Gas phase results. In order to study mechanism of the reactions, structure corresponding to reactants, transition states and products were optimized in level of theory. Figure 1 shows the ...

  10. Al NMR: a novel NMR data processing program optimized for sparse sampling

    Energy Technology Data Exchange (ETDEWEB)

    Gledhill, John M.; Wand, A. Joshua, E-mail: wand@mail.med.upenn.edu [University of Pennsylvania, Graduate Group in Biochemistry and Molecular Biophysics, Perelman School of Medicine (United States)

    2012-01-15

    Sparse sampling in biomolecular multidimensional NMR offers increased acquisition speed and resolution and, if appropriate conditions are met, an increase in sensitivity. Sparse sampling of indirectly detected time domains combined with the direct truly multidimensional Fourier transform has elicited particular attention because of the ability to generate a final spectrum amenable to traditional analysis techniques. A number of sparse sampling schemes have been described including radial sampling, random sampling, concentric sampling and variations thereof. A fundamental feature of these sampling schemes is that the resulting time domain data array is not amenable to traditional Fourier transform based processing and phasing correction techniques. In addition, radial sampling approaches offer a number of advantages and capabilities that are also not accessible using standard NMR processing techniques. These include sensitivity enhancement, sub-matrix processing and determination of minimal sets of sampling angles. Here we describe a new software package (Al NMR) that enables these capabilities in the context of a general NMR data processing environment.

  11. CASD-NMR: critical assessment of automated structure determination by NMR

    NARCIS (Netherlands)

    Rosato, A.; van der Schot, G.; Bonvin, A.M.J.J.|info:eu-repo/dai/nl/113691238

    2009-01-01

    NMR spectroscopy is currently the only technique for determining the solution structure of biological macromolecules. This typically requires both the assignment of resonances and a labor-intensive analysis of multidimensional nuclear Overhauser effect spectroscopy (NOESY) spectra, in which peaks

  12. Perspective: Acoustic metamaterials in transition

    KAUST Repository

    Wu, Ying

    2017-12-15

    Acoustic metamaterials derive their novel characteristics from the interaction between acoustic waves with designed structures. Since its inception seventeen years ago, the field has been driven by fundamental geometric and physical principles that guide the structure design rules as well as provide the basis for wave functionalities. Recent examples include resonance-based acoustic metasurfaces that offer flexible control of acoustic wave propagation such as focusing and re-direction; parity-time (PT)-symmetric acoustics that utilizes the general concept of pairing loss and gain to achieve perfect absorption at a single frequency; and topological phononics that can provide one-way edge state propagation. However, such novel functionalities are not without constraints. Metasurface elements rely on resonances to enhance their coupling to the incident wave; hence, its functionality is limited to a narrow frequency band. Topological phononics is the result of the special lattice symmetry that must be fixed at the fabrication stage. Overcoming such constraints naturally forms the basis for further developments. We identify two emergent directions: Integration of acoustic metamaterial elements for achieving broadband characteristics as well as acoustic wave manipulation tasks more complex than the single demonstrative functionality; and active acoustic metamaterials that can adapt to environment as well as to go beyond the constraints on the passive acoustic metamaterials. Examples of a successful recent integration of multi-resonators in achieving broadband sound absorption can be found in optimal sound-absorbing structures, which utilize causality constraint as a design tool in realizing the target-set absorption spectrum with a minimal sample thickness. Active acoustic metamaterials have also demonstrated the capability to tune bandgaps as well as to alter property of resonances in real time through stiffening of the spring constants, in addition to the PT symmetric

  13. An asymptotic model in acoustics: acoustic drift equations.

    Science.gov (United States)

    Vladimirov, Vladimir A; Ilin, Konstantin

    2013-11-01

    A rigorous asymptotic procedure with the Mach number as a small parameter is used to derive the equations of mean flows which coexist and are affected by the background acoustic waves in the limit of very high Reynolds number.

  14. Petrophysical properties of greensand as predicted from NMR measurements

    DEFF Research Database (Denmark)

    Hossain, Zakir; Grattoni, Carlos A.; Solymar, Mikael

    2011-01-01

    ABSTRACT: Nuclear magnetic resonance (NMR) is a useful tool in reservoir evaluation. The objective of this study is to predict petrophysical properties from NMR T2 distributions. A series of laboratory experiments including core analysis, capillary pressure measurements, NMR T2 measurements...

  15. Recent excitements in protein NMR: Large proteins and biologically ...

    Indian Academy of Sciences (India)

    2016-10-14

    Oct 14, 2016 ... Paramagnetic NMR. Paramagnetism arises from unpaired electrons. As the mag- netic moment of electrons is ~1000 times more than protons, the presence of an unpaired electron near the nucleus causes pronounced paramagnetic effects; leading to dramatic out- come of NMR spectra. As, NMR restraints ...

  16. OPENCORE NMR: open-source core modules for implementing an integrated FPGA-based NMR spectrometer.

    Science.gov (United States)

    Takeda, Kazuyuki

    2008-06-01

    A tool kit for implementing an integrated FPGA-based NMR spectrometer [K. Takeda, A highly integrated FPGA-based nuclear magnetic resonance spectrometer, Rev. Sci. Instrum. 78 (2007) 033103], referred to as the OPENCORE NMR spectrometer, is open to public. The system is composed of an FPGA chip and several peripheral boards for USB communication, direct-digital synthesis (DDS), RF transmission, signal acquisition, etc. Inside the FPGA chip have been implemented a number of digital modules including three pulse programmers, the digital part of DDS, a digital quadrature demodulator, dual digital low-pass filters, and a PC interface. These FPGA core modules are written in VHDL, and their source codes are available on our website. This work aims at providing sufficient information with which one can, given some facility in circuit board manufacturing, reproduce the OPENCORE NMR spectrometer presented here. Also, the users are encouraged to modify the design of spectrometer according to their own specific needs. A home-built NMR spectrometer can serve complementary roles to a sophisticated commercial spectrometer, should one comes across such new ideas that require heavy modification to hardware inside the spectrometer. This work can lower the barrier of building a handmade NMR spectrometer in the laboratory, and promote novel and exciting NMR experiments.

  17. Effects of subsampling of passive acoustic recordings on acoustic metrics.

    Science.gov (United States)

    Thomisch, Karolin; Boebel, Olaf; Zitterbart, Daniel P; Samaran, Flore; Van Parijs, Sofie; Van Opzeeland, Ilse

    2015-07-01

    Passive acoustic monitoring is an important tool in marine mammal studies. However, logistics and finances frequently constrain the number and servicing schedules of acoustic recorders, requiring a trade-off between deployment periods and sampling continuity, i.e., the implementation of a subsampling scheme. Optimizing such schemes to each project's specific research questions is desirable. This study investigates the impact of subsampling on the accuracy of two common metrics, acoustic presence and call rate, for different vocalization patterns (regimes) of baleen whales: (1) variable vocal activity, (2) vocalizations organized in song bouts, and (3) vocal activity with diel patterns. To this end, above metrics are compared for continuous and subsampled data subject to different sampling strategies, covering duty cycles between 50% and 2%. The results show that a reduction of the duty cycle impacts negatively on the accuracy of both acoustic presence and call rate estimates. For a given duty cycle, frequent short listening periods improve accuracy of daily acoustic presence estimates over few long listening periods. Overall, subsampling effects are most pronounced for low and/or temporally clustered vocal activity. These findings illustrate the importance of informed decisions when applying subsampling strategies to passive acoustic recordings or analyses for a given target species.

  18. Simulation of Acoustics for Ares I Scale Model Acoustic Tests

    Science.gov (United States)

    Putnam, Gabriel; Strutzenberg, Louise L.

    2011-01-01

    The Ares I Scale Model Acoustics Test (ASMAT) is a series of live-fire tests of scaled rocket motors meant to simulate the conditions of the Ares I launch configuration. These tests have provided a well documented set of high fidelity acoustic measurements useful for validation including data taken over a range of test conditions and containing phenomena like Ignition Over-Pressure and water suppression of acoustics. To take advantage of this data, a digital representation of the ASMAT test setup has been constructed and test firings of the motor have been simulated using the Loci/CHEM computational fluid dynamics software. Results from ASMAT simulations with the rocket in both held down and elevated configurations, as well as with and without water suppression have been compared to acoustic data collected from similar live-fire tests. Results of acoustic comparisons have shown good correlation with the amplitude and temporal shape of pressure features and reasonable spectral accuracy up to approximately 1000 Hz. Major plume and acoustic features have been well captured including the plume shock structure, the igniter pulse transient, and the ignition overpressure.

  19. An Experimental Introduction to Acoustics

    Science.gov (United States)

    Black, Andy Nicholas; Magruder, Robert H.

    2017-11-01

    Learning and understanding physics requires more than studying physics texts. It requires doing physics. Doing research is a key opportunity for students to connect physical principles with their everyday experience. A powerful way to introduce students to research and technique is through subjects in which they might find interest. Presented is an experiment that serves to introduce an advanced undergraduate or high school student to conducting research in acoustics via an experiment involving a standard dreadnought acoustic guitar, recording industry-related equipment, and relevant industrial analysis software. This experimental process is applicable to a wide range of acoustical topics including both acoustic and electric instruments. Also, the student has a hands-on experience with relevant audio engineering technology to study physical principles.

  20. PC and PVC Acoustics Demonstrations.

    Science.gov (United States)

    Luzader, Stephen

    1990-01-01

    Described are four musical instruments constructed from polyvinyl chloride (PVC) pipe. The use of computerized synthesizers to play scales and chords is discussed. Suggestions for other illustrations of acoustics are included. (CW)

  1. Frequency Steered Acoustic Transducer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase II project is to fabricate, characterize, and verify performance of a new type of frequency steered acoustic transducer...

  2. Cryogenic Acoustic Suppression Testing Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed project will explore and test the feasibility and effectiveness of using a cryogenic fluid (liquid nitrogen) to facilitate acoustic suppression in a...

  3. Reverberant Acoustic Test Facility (RATF)

    Data.gov (United States)

    Federal Laboratory Consortium — The very large Reverberant Acoustic Test Facility (RATF) at the NASA Glenn Research Center (GRC), Plum Brook Station, is currently under construction and is due to...

  4. PVT Degradation Studies: Acoustic Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Dib, Gerges [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tucker, Brian J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kouzes, Richard T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Smith, Philip J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-04-01

    Under certain environmental conditions, polyvinyl toluene (PVT) plastic scintillator has been observed to undergo internal fogging. This document reports on a study of acoustic techniques to determine whether they can provide a diagnostic for the fogging of PVT. Different ultrasound techniques were employed for detecting the level of internal fogging in PVT, including wave velocity measurements, attenuation, nonlinear acoustics, and acoustic microscopy. The results indicate that there are linear relations between the wave velocity and wave attenuation with the level of internal fogging. The effects of fogging on ultrasound wave attenuation is further verified by acoustic microscopy imaging, where regions with fog in the specimen demonstration higher levels of attenuation compared to clear regions. Results from the nonlinear ultrasound measurements were inconclusive due to high sensitivities to transducer coupling and fixture variabilities.

  5. Isotropic transformation acoustics and applications

    Science.gov (United States)

    Su, Xiaoshi; Norris, Andrew N.

    2017-04-01

    A novel class of acoustic metamaterial is proposed for directional collimation of a cylindrical source into a plane wave beam. The effect is based on transformation acoustics which retains the exact form of the wave equation under conformal mapping from a circular region to a triangular area. The transformation is adjustable, allowing the acoustic energy to be equally radiated in three directions, or preferentially in a single direction. Importantly, the material properties in the physical domain are isotropic and therefore practically realizable. Two example devices are proposed using cylindrical elastic shells in water as the metamaterial elements and demonstrated using full wave simulations. This approach has potential applications beyond acoustic antenna design in beam-steering and wavefront manipulation.

  6. Acoustic Characterization of Mesoscale Objects

    Energy Technology Data Exchange (ETDEWEB)

    Chinn, D; Huber, R; Chambers, D; Cole, G; Balogun, O; Spicer, J; Murray, T

    2007-03-13

    This report describes the science and engineering performed to provide state-of-the-art acoustic capabilities for nondestructively characterizing mesoscale (millimeter-sized) objects--allowing micrometer resolution over the objects entire volume. Materials and structures used in mesoscale objects necessitate the use of (1) GHz acoustic frequencies and (2) non-contacting laser generation and detection of acoustic waves. This effort demonstrated that acoustic methods at gigahertz frequencies have the necessary penetration depth and spatial resolution to effectively detect density discontinuities, gaps, and delaminations. A prototype laser-based ultrasonic system was designed and built. The system uses a micro-chip laser for excitation of broadband ultrasonic waves with frequency components reaching 1.0 GHz, and a path-stabilized Michelson interferometer for detection. The proof-of-concept for mesoscale characterization is demonstrated by imaging a micro-fabricated etched pattern in a 70 {micro}m thick silicon wafer.

  7. Frequency Steered Acoustic Transducer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase I project is to develop, fabricate, and characterize a novel frequency steered acoustic transducer (FSAT) for the...

  8. A programmable nonlinear acoustic metamaterial

    Science.gov (United States)

    Yang, Tianzhi; Song, Zhi-Guang; Clerkin, Eoin; Zhang, Ye-Wei; Sun, Jia-He; Su, Yi-Shu; Chen, Li-Qun; Hagedorn, Peter

    2017-09-01

    Acoustic metamaterials with specifically designed lattices can manipulate acoustic/elastic waves in unprecedented ways. Whereas there are many studies that focus on passive linear lattice, with non-reconfigurable structures. In this letter, we present the design, theory and experimental demonstration of an active nonlinear acoustic metamaterial, the dynamic properties of which can be modified instantaneously with reversibility. By incorporating active and nonlinear elements in a single unit cell, a real-time tunability and switchability of the band gap is achieved. In addition, we demonstrate a dynamic "editing" capability for shaping transmission spectra, which can be used to create the desired band gap and resonance. This feature is impossible to achieve in passive metamaterials. These advantages demonstrate the versatility of the proposed device, paving the way toward smart acoustic devices, such as logic elements, diode and transistor.

  9. Magnetic recording with acoustic waves

    Energy Technology Data Exchange (ETDEWEB)

    Li, Weiyang; Buford, Benjamin; Jander, Albrecht; Dhagat, Pallavi, E-mail: dhagat@eecs.oregonstate.edu

    2014-09-01

    We demonstrate acoustically assisted magnetic recording (AAMR), a new paradigm in magnetic data storage. In this concept, otherwise unwriteable high-coercivity media, requisite for thermally stable high-density data storage, are made amenable to recording by lowering their coercivity via strain induced by surface acoustic waves. The basic principles of AAMR are proven using galfenol, a low-coercivity magnetostrictive material, as the recording medium. It is shown that the writing field needed to record data in the presence of acoustic strain is lower than the coercivity of the unstrained galfenol film. Further, it is demonstrated that interference between acoustic waves can be tailored to selectively address a bit on the recording medium.

  10. Acoustic Multipurpose Cargo Transfer Bag

    Science.gov (United States)

    Baccus, Shelley

    2015-01-01

    The Logistics Reduction (LR) project within the Advanced Exploration Systems (AES) program is tasked with reducing logistical mass and repurposing logistical items. Multipurpose Cargo Transfer Bags (MCTB) are designed to be the same external volume as a regular cargo transfer bag, the common logistics carrier for the International Space Station. After use as a cargo bag, the MCTB can be unzipped and unfolded to be reused. This Acoustic MCTBs transform into acoustic blankets after the initial logistics carrying objective is complete.

  11. Acoustical Properties of Contemporary Mosques

    Directory of Open Access Journals (Sweden)

    Karaman Özgül Yılmaz

    2017-04-01

    Full Text Available Religious buildings are important for many communities because of their representation of different beliefs. In such structures, the sense of individuality or unity & togetherness are created according to variable worship activities; these different uses have also different acoustical requirements. In order to create the desired feeling in the space at the required time, rooms should be evaluated in terms of acoustical conditions.

  12. Automated Acoustic Identification of Bats

    Science.gov (United States)

    2011-10-01

    signals. Other signal sources contribute to the overall acoustic soundscape and interfere with discerning the bat calls from the background signals. In...noises, and the changing soundscape from moving can all exceed at least parts of the signal amplitude of bat calls. The ability to track the trend...results, full-spectrum data also provides an effective voucher for interpretation of the full acoustic soundscape at the time of the recording. Figure

  13. NMR CHARACTERIZATIONS OF PROPERTIES OF HETEROGENEOUS MEDIA

    Energy Technology Data Exchange (ETDEWEB)

    C.T. Philip Chang; Changho Choi; Jeromy T. Hollenshead; Rudi Michalak; Jack Phan; Ramon Saavedra; John C. Slattery; Jinsoo Uh; Randi Valestrand; A. Ted Watson; Song Xue

    2005-01-01

    A critical and long-standing need within the petroleum industry is the specification of suitable petrophysical properties for mathematical simulation of fluid flow in petroleum reservoirs (i.e., reservoir characterization). The development of accurate reservoir characterizations is extremely challenging. Property variations may be described on many scales, and the information available from measurements reflect different scales. In fact, experiments on laboratory core samples, well-log data, well-test data, and reservoir-production data all represent information potentially valuable to reservoir characterization, yet they all reflect information about spatial variations of properties at different scales. Nuclear magnetic resonance (NMR) spectroscopy and imaging (MRI) provide enormous potential for developing new descriptions and understandings of heterogeneous media. NMR has the rare capability to probe permeable media non-invasively, with spatial resolution, and it provides unique information about molecular motions and interactions that are sensitive to morphology. NMR well-logging provides the best opportunity ever to resolve permeability distributions within petroleum reservoirs. We develop MRI methods to determine, for the first time, spatially resolved distributions of porosity and permeability within permeable media samples that approach the intrinsic scale: the finest resolution of these macroscopic properties possible. To our knowledge, this is the first time that the permeability is actually resolved at a scale smaller than the sample. In order to do this, we have developed a robust method to determine of relaxation distributions from NMR experiments and a novel implementation and analysis of MRI experiments to determine the amount of fluid corresponding to imaging regions, which are in turn used to determine porosity and saturation distributions. We have developed a novel MRI experiment to determine velocity distributions within flowing experiments, and

  14. Solid state NMR of biopolymers and synthetic polymers

    Energy Technology Data Exchange (ETDEWEB)

    Jelinski, Lynn W. [Cornell Univ., Geneva, NY (United States)

    1995-12-31

    Solid state NMR has been invaluable in evaluating the structure, phase separation, and dynamics of polymers. Because polymers are generally used in the solid state, solid state NMR is especially powerful because it provides information about the materials in their native state. This review gives a general overview of solid state NMR, concentrating on solid state {sup 13} C and {sup 2} H NMR. It then focuses on two examples: the biopolymer spider silka and the engineering material polyurethane. It illustrates how solid state NMR can provide new information about synthetic and bio-polymers. (author) 11 refs., 5 figs., 3 tabs.

  15. Opto-acoustic cell permeation

    Energy Technology Data Exchange (ETDEWEB)

    Visuri, S R; Heredia, N

    2000-03-09

    Optically generated acoustic waves have been used to temporarily permeate biological cells. This technique may be useful for enhancing transfection of DNA into cells or enhancing the absorption of locally delivered drugs. A diode-pumped frequency-doubled Nd:YAG laser operating at kHz repetition rates was used to produce a series of acoustic pulses. An acoustic wave was formed via thermoelastic expansion by depositing laser radiation into an absorbing dye. Generated pressures were measured with a PVDF hydrophone. The acoustic waves were transmitted to cultured and plated cells. The cell media contained a selection of normally- impermeable fluorescent-labeled dextran dyes. Following treatment with the opto-acoustic technique, cellular incorporation of dyes, up to 40,000 Molecular Weight, was noted. Control cells that did not receive opto-acoustic treatment had unremarkable dye incorporation. Uptake of dye was quantified via fluorescent microscopic analysis. Trypan Blue membrane exclusion assays and fluorescent labeling assays confirmed the vitality of cells following treatment. This method of enhanced drug delivery has the potential to dramatically reduce required drug dosages and associated side effects and enable revolutionary therapies.

  16. Acoustical evaluation of preschool classrooms

    Science.gov (United States)

    Yang, Wonyoung; Hodgson, Murray

    2003-10-01

    An investigation was made of the acoustical environments in the Berwick Preschool, Vancouver, in response to complaints by the teachers. Reverberation times (RT), background noise levels (BNL), and in-class sound levels (Leq) were measured for acoustical evaluation in the classrooms. With respect to the measured RT and BNL, none of the classrooms in the preschool were acceptable according to the criteria relevant to this study. A questionnaire was administered to the teachers to assess their subjective responses to the acoustical and nonacoustical environments of the classrooms. Teachers agreed that the nonacoustical environments in the classrooms were fair, but that the acoustical environments had problems. Eight different classroom configurations were simulated to improve the acoustical environments, using the CATT room acoustical simulation program. When the surface absorption was increased, both the RT and speech levels decreased. RASTI was dependent on the volumes of the classrooms when the background noise levels were high; however, it depended on the total absorption of the classrooms when the background noise levels were low. Ceiling heights are critical as well. It is recommended that decreasing the volume of the classrooms is effective. Sound absorptive materials should be added to the walls or ceiling.

  17. Acoustics Research of Propulsion Systems

    Science.gov (United States)

    Gao, Ximing; Houston, Janice

    2014-01-01

    The liftoff phase induces high acoustic loading over a broad frequency range for a launch vehicle. These external acoustic environments are used in the prediction of the internal vibration responses of the vehicle and components. Present liftoff vehicle acoustic environment prediction methods utilize stationary data from previously conducted hold-down tests to generate 1/3 octave band Sound Pressure Level (SPL) spectra. In an effort to update the accuracy and quality of liftoff acoustic loading predictions, non-stationary flight data from the Ares I-X were processed in PC-Signal in two flight phases: simulated hold-down and liftoff. In conjunction, the Prediction of Acoustic Vehicle Environments (PAVE) program was developed in MATLAB to allow for efficient predictions of sound pressure levels (SPLs) as a function of station number along the vehicle using semi-empirical methods. This consisted of generating the Dimensionless Spectrum Function (DSF) and Dimensionless Source Location (DSL) curves from the Ares I-X flight data. These are then used in the MATLAB program to generate the 1/3 octave band SPL spectra. Concluding results show major differences in SPLs between the hold-down test data and the processed Ares I-X flight data making the Ares I-X flight data more practical for future vehicle acoustic environment predictions.

  18. NMR shielding calculations across the periodic table: diamagnetic uranium compounds. 2. Ligand and metal NMR.

    Science.gov (United States)

    Schreckenbach, Georg

    2002-12-16

    In this and a previous article (J. Phys. Chem. A 2000, 104, 8244), the range of application for relativistic density functional theory (DFT) is extended to the calculation of nuclear magnetic resonance (NMR) shieldings and chemical shifts in diamagnetic actinide compounds. Two relativistic DFT methods are used, ZORA ("zeroth-order regular approximation") and the quasirelativistic (QR) method. In the given second paper, NMR shieldings and chemical shifts are calculated and discussed for a wide range of compounds. The molecules studied comprise uranyl complexes, [UO(2)L(n)](+/-)(q); UF(6); inorganic UF(6) derivatives, UF(6-n)Cl(n), n = 0-6; and organometallic UF(6) derivatives, UF(6-n)(OCH(3))(n), n = 0-5. Uranyl complexes include [UO(2)F(4)](2-), [UO(2)Cl(4)](2-), [UO(2)(OH)(4)](2-), [UO(2)(CO(3))(3)](4-), and [UO(2)(H(2)O)(5)](2+). For the ligand NMR, moderate (e.g., (19)F NMR chemical shifts in UF(6-n)Cl(n)) to excellent agreement [e.g., (19)F chemical shift tensor in UF(6) or (1)H NMR in UF(6-n)(OCH(3))(n)] has been found between theory and experiment. The methods have been used to calculate the experimentally unknown (235)U NMR chemical shifts. A large chemical shift range of at least 21,000 ppm has been predicted for the (235)U nucleus. ZORA spin-orbit appears to be the most accurate method for predicting actinide metal chemical shifts. Trends in the (235)U NMR chemical shifts of UF(6-n)L(n) molecules are analyzed and explained in terms of the calculated electronic structure. It is argued that the energy separation and interaction between occupied and virtual orbitals with f-character are the determining factors.

  19. Incorporating Realistic Acoustic Propagation Models in Simulation of Underwater Acoustic Networks: A Statistical Approach

    National Research Council Canada - National Science Library

    Xie, Geoffrey; Gibson, John; Diaz-Gonzalez, Leopoldo

    2006-01-01

    .... The validity of the simulation results becomes questionable. There are, though, very high fidelity models developed by acoustic engineers and physicists for predicting acoustic propagation characteristics...

  20. Solid-state NMR basic principles and practice

    CERN Document Server

    Apperley, David C; Hodgkinson, Paul

    2014-01-01

    Nuclear Magnetic Resonance (NMR) has proved to be a uniquely powerful and versatile tool for analyzing and characterizing chemicals and materials of all kinds. This book focuses on the latest developments and applications for "solid-state" NMR, which has found new uses from archaeology to crystallography to biomaterials and pharmaceutical science research. The book will provide materials engineers, analytical chemists, and physicists, in and out of lab, a survey of the techniques and the essential tools of solid-state NMR, together with a practical guide on applications. In this concise introduction to the growing field of solid-state nuclear magnetic resonance spectroscopy The reader will find: * Basic NMR concepts for solids, including guidance on the spin-1/2 nuclei concept * Coverage of the quantum mechanics aspects of solid state NMR and an introduction to the concept of quadrupolar nuclei * An understanding relaxation, exchange and quantitation in NMR * An analysis and interpretation of NMR data, with e...

  1. Multiecho scheme advances surface NMR for aquifer characterization

    Science.gov (United States)

    Grunewald, Elliot; Walsh, David

    2013-12-01

    nuclear magnetic resonance (NMR) is increasingly used as a method to noninvasively characterize aquifers. This technology follows a successful history of NMR logging, applied over decades to estimate hydrocarbon reservoir properties. In contrast to logging, however, surface methods have utilized relatively simple acquisition sequences, from which pore-scale properties may not be reliably and efficiently estimated. We demonstrate for the first time the capability of sophisticated multiecho measurements to rapidly record a surface NMR response that more directly reflects aquifer characteristics. Specifically, we develop an adaptation of the multipulse Carr-Purcell-Meiboom-Gill (CPMG) sequence, widely used in logging, to measure the T2 relaxation response in a single scan. We validate this approach in a field surface NMR data set and by direct comparison with an NMR log. Adoption of the CPMG marked a landmark advancement in the history of logging NMR; we have now realized this same advancement in the surface NMR method.

  2. Contour mode resonators with acoustic reflectors

    Science.gov (United States)

    Olsson, Roy H [Albuquerque, NM; Fleming, James G [Albuquerque, NM; Tuck, Melanie R [Albuquerque, NM

    2008-06-10

    A microelectromechanical (MEM) resonator is disclosed which has a linear or ring-shaped acoustic resonator suspended above a substrate by an acoustic reflector. The acoustic resonator can be formed with a piezoelectric material (e.g. aluminum nitride, zinc oxide or PZT), or using an electrostatically-actuated material. The acoustic reflector (also termed an acoustic mirror) uses alternating sections of a relatively low acoustic impedance Z.sub.L material and a relatively high acoustic impedance Z.sub.H material to isolate the acoustic resonator from the substrate. The MEM resonator, which can be formed on a silicon substrate with conventional CMOS circuitry, has applications for forming oscillators, rf filters, and acoustic sensors.

  3. NMR-based diffusion lattice imaging.

    Science.gov (United States)

    Laun, Frederik Bernd; Müller, Lars; Kuder, Tristan Anselm

    2016-03-01

    Nuclear magnetic resonance (NMR) diffusion experiments are widely employed as they yield information about structures hindering the diffusion process, e.g., about cell membranes. While it has been shown in recent articles that these experiments can be used to determine the shape of closed pores averaged over a volume of interest, it is still an open question how much information can be gained in open well-connected systems. In this theoretical work, it is shown that the full structure information of connected periodic systems is accessible. To this end, the so-called "SEquential Rephasing by Pulsed field-gradient Encoding N Time intervals" (SERPENT) sequence is used, which employs several diffusion encoding gradient pulses with different amplitudes. Two two-dimensional solid matrices that are surrounded by an NMR-visible medium are considered: a hexagonal lattice of cylinders and a rectangular lattice of isosceles triangles.

  4. NMR-based diffusion lattice imaging

    Science.gov (United States)

    Laun, Frederik Bernd; Müller, Lars; Kuder, Tristan Anselm

    2016-03-01

    Nuclear magnetic resonance (NMR) diffusion experiments are widely employed as they yield information about structures hindering the diffusion process, e.g., about cell membranes. While it has been shown in recent articles that these experiments can be used to determine the shape of closed pores averaged over a volume of interest, it is still an open question how much information can be gained in open well-connected systems. In this theoretical work, it is shown that the full structure information of connected periodic systems is accessible. To this end, the so-called "SEquential Rephasing by Pulsed field-gradient Encoding N Time intervals" (SERPENT) sequence is used, which employs several diffusion encoding gradient pulses with different amplitudes. Two two-dimensional solid matrices that are surrounded by an NMR-visible medium are considered: a hexagonal lattice of cylinders and a rectangular lattice of isosceles triangles.

  5. Strange kinetics, porous media, and NMR

    Energy Technology Data Exchange (ETDEWEB)

    Kimmich, Rainer

    2002-11-01

    Nuclear magnetic resonance (NMR) techniques cover a broad range of length and time scales on which dynamic properties of fluids confined in porous media can be investigated. This report refers to field-cycling NMR relaxometry, field gradient NMR diffusometry and NMR microscopy. The objective was to examine diffusion, hydrodynamic dispersion, flow, and thermal convection under the influence of geometrical confinements and surface interactions in porous media. The anomalous character of these phenomena will be demonstrated and discussed in comparison with computer simulations and theoretical concepts. The first part of this presentation is devoted to nanoporous samples. It is shown that molecular Levy walks along inner surfaces occur under certain conditions. Mutual 'obstruction' of molecules in molecular sieves and zeolites is another source of diffusion anomaly known as single-file diffusion which can be described by Gaussian propagators with a diffusion coefficient depending on time in a certain limit. In the case of polymers confined in narrow artificial tubes of a porous solid matrix, the characteristics of reptation were experimentally verified. The second part mainly refers to 'trapping' effects as a source of anomalous transport characterised by non-Gaussian propagators. Model objects fabricated on the basis of percolation cluster models were examined with respect to flow, diffusion, thermal convection and hydrodynamic dispersion. The elucidation of transport laws in model systems of well defined and mathematically describable geometries is considered to be a promising way for the exploration of the structure/dynamics relationship in porous media as a long-term objective.

  6. Structure of high-resolution NMR spectra

    CERN Document Server

    Corio, PL

    2012-01-01

    Structure of High-Resolution NMR Spectra provides the principles, theories, and mathematical and physical concepts of high-resolution nuclear magnetic resonance spectra.The book presents the elementary theory of magnetic resonance; the quantum mechanical theory of angular momentum; the general theory of steady state spectra; and multiple quantum transitions, double resonance and spin echo experiments.Physicists, chemists, and researchers will find the book a valuable reference text.

  7. NMR characteristics of rat mammary tumors

    Energy Technology Data Exchange (ETDEWEB)

    Osbakken, M.; Kreider, J.; Taczanowsky, P.

    1984-01-01

    12 rats were injected intradermally with 13762A rat mammary adenocarcinoma (1 x 10/sup 6/ cells). 3 rats died before completion of the study and 2 rat had tumor regression; the first 3 were excluded from data analysis. NMR imaging with a 1.5K gauss resistive magnet at 2, 3, 4, and 5 weeks after injection demonstrated increasing tumor mass. Saturation recovery (SR), inversion recovery (IR), and spin echo (SE) pulse sequence images and T/sub 1/ calculation were done for tumor characterization. (Tumor size was too small to identify at 2 weeks.) 3 rats were sacrificed after the last 3 imaging periods for histological studies, done to distinguish solid tumor mass from necrosis. Planimetry of tumor areas showed that as tumors grew in size, the ratio of necrotic area to area of solid tumor increased (week 3 = .3 +- .11; week 4 = .45 +- .07; week 5 = .51 +- 05); simultaneous calculated T/sub 1/ values also increased (week 3 = .35 +- .15; week 4 = .45 +- .06; week 5 = .42 +- 03). Qualitative NMR image T/sub 1/ values also increased as evidenced by progression of SR and IR tumor image intensity from very bright compared to the rest of the body at week 3 to less intense than other structures at week 5. These findings indicate that change in T/sub 1/ may be secondary to the pathophysiological change in the tumor (the increasing in necrosis, associated with increased free water). Thus, the range of T/sub 1/ values obtained in tumors in this study (and in previous studies) may be due to change in tumor physiology and anatomy. Careful correlation of histological with NMR data may allow ultimate use of NMR relaxation characteristics for determination of the physiological state of tumors.

  8. Quantitative calibration of radiofrequency NMR Stark effects.

    Science.gov (United States)

    Tarasek, Matthew R; Kempf, James G

    2011-10-01

    Nuclear magnetic resonance (NMR) Stark responses can occur in quadrupolar nuclei for an electric field oscillating at twice the usual NMR frequency (2ω(0)). Calibration of responses to an applied E field is needed to establish nuclear spins as probes of native E fields within material and molecular systems. We present an improved approach and apparatus for accurate measurement of quadrupolar Stark effects. Updated values of C(14) (the response parameter in cubic crystals) were obtained for both (69)Ga and (75)As in GaAs. Keys to improvement include a modified implementation of voltage dividers to assess the 2ω(0) amplitude, |E|, and the stabilization of divider response by reduction of stray couplings in 2ω(0) circuitry. Finally, accuracy was enhanced by filtering sets of |E| through a linear response function that we established for the radiofrequency amplifier. Our approach is verified by two types of spectral results. Steady-state 2ω(0) excitation to presaturate NMR spectra yielded C(14) = (2.59 ± 0.06) × 10(12) m(-1) for (69)Ga at room-temperature and 14.1 T. For (75)As, we obtained (3.1 ± 0.1) × 10(12) m(-1). Both values reconcile with earlier results from 77 K and below 1 T, whereas current experiments are at room temperature and 14.1 T. Finally, we present results where few-microsecond pulses of the 2ω(0) field induced small (tens of Hz) changes in high-resolution NMR line shapes. There too, spectra collected vs |E| agree with the model for response, further establishing the validity of our protocols to specify |E|.

  9. 3D Reconstruction of NMR Images

    Directory of Open Access Journals (Sweden)

    Peter Izak

    2007-01-01

    Full Text Available This paper introduces experiment of 3D reconstruction NMR images scanned from magnetic resonance device. There are described methods which can be used for 3D reconstruction magnetic resonance images in biomedical application. The main idea is based on marching cubes algorithm. For this task was chosen sophistication method by program Vision Assistant, which is a part of program LabVIEW.

  10. Teaching acoustics courses online

    Science.gov (United States)

    Burroughs, Courtney B.

    2003-04-01

    Three graduate-level courses in noise control engineering have been taught by the Graduate Program in Acoustics through the Penn State World Campus for more than four years. In each course, students receive (1) a study guide which gives an overview of the course, the software, and assignments, and (2) a CD which contains the content of the course with animations embedded in the text. Because all communications are online, students have been able to take these courses asynchronously on their own schedule with minimum disruptions in their home and work schedules. Students work on group projects, known as collaborative learning activities, and conduct simulated measurements using virtual instruments. Individual learning activities include study questions, written problems, computer coding, and interactive demonstrations. The first course has been offered four times and several students have completed all three courses. Overviews of the elements of these online courses that have been successful and the elements that have presented problems, along with a discussion of adjustments that we have been able to make and those that we would like to make to improve the courses, will be presented.

  11. Acoustics of the Intonarumori

    Science.gov (United States)

    Serafin, Stefania

    2005-04-01

    The Intonarumori were a family of musical instruments invented by the Italian futurist composer and painter Luigi Russolo. Each Intonarumori was made of a wooden parallelepiped sound box, inside which a wheel of different sizes and materials was setting into vibration a catgut or metal string. The pitch of the string was varied by using a lever, while the speed of the wheel was controlled by the performer using a crank. At one end of the string there was a drumhead that transmitted vibrations to the speaker. Unfortunately, all the original Intonarumori were destroyed after a fire during World War II. Since then, researchers have tried to understand the sound production mechanism of such instruments, especially by consulting the patents compiled by Russolo or by reading his book ``The art of noise.'' In this paper we describe the acoustics of the Intonarumori. Based on such description, we propose physical models that simulate such instruments. The intonarumori's string is modeled using a one dimensional waveguide, which is excited either by an impact or a friction model. The body of the instrument is modeled using a 3-D rectangular mesh, while the horn is considered as an omnidirectional radiator.

  12. NMR studies of dynamic biomolecular conformational ensembles.

    Science.gov (United States)

    Torchia, Dennis A

    2015-02-01

    Multidimensional heteronuclear NMR approaches can provide nearly complete sequential signal assignments of isotopically enriched biomolecules. The availability of assignments together with measurements of spin relaxation rates, residual spin interactions, J-couplings and chemical shifts provides information at atomic resolution about internal dynamics on timescales ranging from ps to ms, both in solution and in the solid state. However, due to the complexity of biomolecules, it is not possible to extract a unique atomic-resolution description of biomolecular motions even from extensive NMR data when many conformations are sampled on multiple timescales. For this reason, powerful computational approaches are increasingly applied to large NMR data sets to elucidate conformational ensembles sampled by biomolecules. In the past decade, considerable attention has been directed at an important class of biomolecules that function by binding to a wide variety of target molecules. Questions of current interest are: "Does the free biomolecule sample a conformational ensemble that encompasses the conformations found when it binds to various targets; and if so, on what time scale is the ensemble sampled?" This article reviews recent efforts to answer these questions, with a focus on comparing ensembles obtained for the same biomolecules by different investigators. A detailed comparison of results obtained is provided for three biomolecules: ubiquitin, calmodulin and the HIV-1 trans-activation response RNA. Published by Elsevier B.V.

  13. Principles of high resolution NMR in solids

    CERN Document Server

    Mehring, Michael

    1983-01-01

    The field of Nuclear Magnetic Resonance (NMR) has developed at a fascinating pace during the last decade. It always has been an extremely valuable tool to the organic chemist by supplying molecular "finger print" spectra at the atomic level. Unfortunately the high resolution achievable in liquid solutions could not be obtained in solids and physicists and physical chemists had to live with unresolved lines open to a wealth of curve fitting procedures and a vast amount of speculations. High resolution NMR in solids seemed to be a paradoxon. Broad structure­ less lines are usually encountered when dealing with NMR in solids. Only with the recent advent of mUltiple pulse, magic angle, cross-polarization, two-dimen­ sional and multiple-quantum spectroscopy and other techniques during the last decade it became possible to resolve finer details of nuclear spin interactions in solids. I have felt that graduate students, researchers and others beginning to get involved with these techniques needed a book which trea...

  14. Structural characterization of Heusler compounds using NMR

    Energy Technology Data Exchange (ETDEWEB)

    Wurmehl, Sabine; Fecher, Gerhard; Balke, Benjamin; Ksenofontov, Vadim; Jung, Verena; Felser, Claudia [Johannes Gutenberg - Universitaet, 55099 Mainz (Germany); Wojcik, Marek [Institute of Physics, Polish Academy of Sciences, 02-668 Warszawa (Poland)

    2007-07-01

    The L2{sub 1} ordered Heusler alloys Co{sub 2}Mn{sub 1-x}Fe{sub x}Si with 0{<=}x{<=}1 attracted much scientific interest, as they are predicted to show high spin polarisation at the Fermi-energy. Therefore Co{sub 2}Mn{sub 1-x}Fe{sub x}Si samples were investigated using spin echo nuclear magnetic resonance (NMR) measurements. This method provides a tool to measure the hyperfine fields. The hyperfine fields represent a very sensitive local probe to order-disorder phenomena. The NMR measurements of polycrystalline Co{sub 2}FeSi samples exhibit a two-peak spectrum with an additional shoulder. This additional signals are attributed to second-order quadrupole splitting, a so called asymmetric line broadening and might be caused by tension within the structure (strain). This effect occurs even in highly ordered systems. Thus previous structural results are corroborated, demonstrating even locally a very high degree of order in Co{sub 2}FeSi. The NMR spectra of the series Co{sub 2}Mn{sub 1-x}Fe{sub x}Si (0.1{<=}x{<=}0.9) exhibit multiplet structures. These might be explained by quadrupole splitting and statistical distribution of Mn and Fe atoms on the Mn site. In summary, the high degree of order in Co{sub 2}Mn{sub 1-x}Fe{sub x}Si is shown.

  15. Multispectral dual isotope and NMR image analysis

    Energy Technology Data Exchange (ETDEWEB)

    Vannier, M.W.; Beihn, R.M.; Butterfield, R.L.; De Land, F.H.

    1985-05-01

    Dual isotope scintigraphy and nuclear magnetic resonance imaging produce image data that is intrinsically multispectral. That is multiple images of the same anatomic region are generated with different gray scale distribution and morphologic content that is largely redundant. Image processing technology, originally developed by NASA for satellite imaging, is available for multispectral analysis. These methods have been applied to provide tissue characterization. Tissue specific information encoded in the grapy scale data from dual isotope and NMR studies may be extracted using multispectral pattern recognition methods. The authors used table lookup minimum distance, maximum likelihood and cluster analysis techniques with data sets from Ga-67 / Tc-99m, 1-131 labeled antibodies / Tc-99m, Tc-99m perfusion / Xe-133 ventilation, and NMR studies. The results show; tissue characteristic signatures exist in dual isotope and NMR imaging, and these spectral signatures are identifiable using multispectral image analysis and provide tissue classification maps with scatter diagrams that facilitate interpretation and assist in elucidating subtle changes.

  16. Protein NMR structures refined without NOE data.

    Science.gov (United States)

    Ryu, Hyojung; Kim, Tae-Rae; Ahn, SeonJoo; Ji, Sunyoung; Lee, Jinhyuk

    2014-01-01

    The refinement of low-quality structures is an important challenge in protein structure prediction. Many studies have been conducted on protein structure refinement; the refinement of structures derived from NMR spectroscopy has been especially intensively studied. In this study, we generated flat-bottom distance potential instead of NOE data because NOE data have ambiguity and uncertainty. The potential was derived from distance information from given structures and prevented structural dislocation during the refinement process. A simulated annealing protocol was used to minimize the potential energy of the structure. The protocol was tested on 134 NMR structures in the Protein Data Bank (PDB) that also have X-ray structures. Among them, 50 structures were used as a training set to find the optimal "width" parameter in the flat-bottom distance potential functions. In the validation set (the other 84 structures), most of the 12 quality assessment scores of the refined structures were significantly improved (total score increased from 1.215 to 2.044). Moreover, the secondary structure similarity of the refined structure was improved over that of the original structure. Finally, we demonstrate that the combination of two energy potentials, statistical torsion angle potential (STAP) and the flat-bottom distance potential, can drive the refinement of NMR structures.

  17. Focusing of Acoustic Waves through Acoustic Materials with Subwavelength Structures

    KAUST Repository

    Xiao, Bingmu

    2013-05-01

    In this thesis, wave propagation through acoustic materials with subwavelength slits structures is studied. Guided by the findings, acoustic wave focusing is achieved with a specific material design. By using a parameter retrieving method, an effective medium theory for a slab with periodic subwavelength cut-through slits is successfully derived. The theory is based on eigenfunction solutions to the acoustic wave equation. Numerical simulations are implemented by the finite-difference time-domain (FDTD) method for the two-dimensional acoustic wave equation. The theory provides the effective impedance and refractive index functions for the equivalent medium, which can reproduce the transmission and reflection spectral responses of the original structure. I analytically and numerically investigate both the validity and limitations of the theory, and the influences of material and geometry on the effective spectral responses are studied. Results show that large contrasts in impedance and density are conditions that validate the effective medium theory, and this approximation displays a better accuracy for a thick slab with narrow slits in it. Based on the effective medium theory developed, a design of a at slab with a snake shaped" subwavelength structure is proposed as a means of achieving acoustic focusing. The property of focusing is demonstrated by FDTD simulations. Good agreement is observed between the proposed structure and the equivalent lens pre- dicted by the theory, which leads to robust broadband focusing by a thin at slab.

  18. Guiding automated NMR structure determination using a global optimization metric, the NMR DP score.

    Science.gov (United States)

    Huang, Yuanpeng Janet; Mao, Binchen; Xu, Fei; Montelione, Gaetano T

    2015-08-01

    ASDP is an automated NMR NOE assignment program. It uses a distinct bottom-up topology-constrained network anchoring approach for NOE interpretation, with 2D, 3D and/or 4D NOESY peak lists and resonance assignments as input, and generates unambiguous NOE constraints for iterative structure calculations. ASDP is designed to function interactively with various structure determination programs that use distance restraints to generate molecular models. In the CASD-NMR project, ASDP was tested and further developed using blinded NMR data, including resonance assignments, either raw or manually-curated (refined) NOESY peak list data, and in some cases (15)N-(1)H residual dipolar coupling data. In these blinded tests, in which the reference structure was not available until after structures were generated, the fully-automated ASDP program performed very well on all targets using both the raw and refined NOESY peak list data. Improvements of ASDP relative to its predecessor program for automated NOESY peak assignments, AutoStructure, were driven by challenges provided by these CASD-NMR data. These algorithmic improvements include (1) using a global metric of structural accuracy, the discriminating power score, for guiding model selection during the iterative NOE interpretation process, and (2) identifying incorrect NOESY cross peak assignments caused by errors in the NMR resonance assignment list. These improvements provide a more robust automated NOESY analysis program, ASDP, with the unique capability of being utilized with alternative structure generation and refinement programs including CYANA, CNS, and/or Rosetta.

  19. CcpNmr AnalysisAssign: a flexible platform for integrated NMR analysis

    Energy Technology Data Exchange (ETDEWEB)

    Skinner, Simon P.; Fogh, Rasmus H. [University of Leicester, Department of Molecular and Cell Biology, Leicester Institute for Structural- and Chemical Biology (United Kingdom); Boucher, Wayne [University of Cambridge, Department of Biochemistry (United Kingdom); Ragan, Timothy J.; Mureddu, Luca G.; Vuister, Geerten W., E-mail: gv29@le.ac.uk [University of Leicester, Department of Molecular and Cell Biology, Leicester Institute for Structural- and Chemical Biology (United Kingdom)

    2016-10-15

    NMR spectroscopy is an indispensably powerful technique for the analysis of biomolecules under ambient conditions, both for structural- and functional studies. However, in practice the complexity of the technique has often frustrated its application by non-specialists. In this paper, we present CcpNmr version-3, the latest software release from the Collaborative Computational Project for NMR, for all aspects of NMR data analysis, including liquid- and solid-state NMR data. This software has been designed to be simple, functional and flexible, and aims to ensure that routine tasks can be performed in a straightforward manner. We have designed the software according to modern software engineering principles and leveraged the capabilities of modern graphics libraries to simplify a variety of data analysis tasks. We describe the process of backbone assignment as an example of the flexibility and simplicity of implementing workflows, as well as the toolkit used to create the necessary graphics for this workflow. The package can be downloaded from www.ccpn.ac.uk/v3-software/downloads http://www.ccpn.ac.uk/v3-software/downloads and is freely available to all non-profit organisations.

  20. NMR spectroscopy of experimentally shocked single crystal quartz: A reexamination of the NMR shock barometer

    Science.gov (United States)

    Fiske, P. S.; Gratz, A. J.; Nellis, W. J.

    1993-01-01

    Cygan and others report a broadening of the Si-29 nuclear magnetic resonance (NMR) peak for synthetic quartz powders with increasing shock pressure which they propose as a shock wave barometer for natural systems. These results are expanded by studying single crystal quartz shocked to 12 and 33 GPa using the 6.5 m two-stage light-gas gun at Lawrence Livermore National Laboratories. Our NMR results differ substantially from those of Cygan and others and suggest that the proposed shock wave barometer may require refinement. The difference in results between this study and that of Cygan and others is most likely caused by different starting materials (single crystal vs. powder) and different shock loading histories. NMR results from single crystal studies may be more applicable to natural systems.

  1. Sonification of acoustic emission data

    Science.gov (United States)

    Raith, Manuel; Große, Christian

    2014-05-01

    While loading different specimens, acoustic emissions appear due to micro crack formation or friction of already existing crack edges. These acoustic emissions can be recorded using suitable ultrasonic transducers and transient recorders. The analysis of acoustic emissions can be used to investigate the mechanical behavior of different specimens under load. Our working group has undertaken several experiments, monitored with acoustic emission techniques. Different materials such as natural stone, concrete, wood, steel, carbon composites and bone were investigated. Also the experimental setup has been varied. Fire-spalling experiments on ultrahigh performance concrete and pullout experiments on bonded anchors have been carried out. Furthermore uniaxial compression tests on natural stone and animal bone had been conducted. The analysis tools include not only the counting of events but the analysis of full waveforms. Powerful localization algorithms and automatic onset picking techniques (based on Akaikes Information Criterion) were established to handle the huge amount of data. Up to several thousand events were recorded during experiments of a few minutes. More sophisticated techniques like moment tensor inversion have been established on this relatively small scale as well. Problems are related to the amount of data but also to signal-to-noise quality, boundary conditions (reflections) sensor characteristics and unknown and changing Greens functions of the media. Some of the acoustic emissions recorded during these experiments had been transferred into audio range. The transformation into the audio range was done using Matlab. It is the aim of the sonification to establish a tool that is on one hand able to help controlling the experiment in-situ and probably adjust the load parameters according to the number and intensity of the acoustic emissions. On the other hand sonification can help to improve the understanding of acoustic emission techniques for training

  2. Acoustic constituents of prosodic typology

    Science.gov (United States)

    Komatsu, Masahiko

    Different languages sound different, and considerable part of it derives from the typological difference of prosody. Although such difference is often referred to as lexical accent types (stress accent, pitch accent, and tone; e.g. English, Japanese, and Chinese respectively) and rhythm types (stress-, syllable-, and mora-timed rhythms; e.g. English, Spanish, and Japanese respectively), it is unclear whether these types are determined in terms of acoustic properties, The thesis intends to provide a potential basis for the description of prosody in terms of acoustics. It argues for the hypothesis that the source component of the source-filter model (acoustic features) approximately corresponds to prosody (linguistic features) through several experimental-phonetic studies. The study consists of four parts. (1) Preliminary experiment: Perceptual language identification tests were performed using English and Japanese speech samples whose frequency spectral information (i.e. non-source component) is heavily reduced. The results indicated that humans can discriminate languages with such signals. (2) Discussion on the linguistic information that the source component contains: This part constitutes the foundation of the argument of the thesis. Perception tests of consonants with the source signal indicated that the source component carries the information on broad categories of phonemes that contributes to the creation of rhythm. (3) Acoustic analysis: The speech samples of Chinese, English, Japanese, and Spanish, differing in prosodic types, were analyzed. These languages showed difference in acoustic characteristics of the source component. (4) Perceptual experiment: A language identification test for the above four languages was performed using the source signal with its acoustic features parameterized. It revealed that humans can discriminate prosodic types solely with the source features and that the discrimination is easier as acoustic information increases. The

  3. Protein Structure Determination Using Protein Threading and Sparse NMR Data

    Energy Technology Data Exchange (ETDEWEB)

    Crawford, O.H.; Einstein, J.R.; Xu, D.; Xu, Y.

    1999-11-14

    It is well known that the NMR method for protein structure determination applies to small proteins and that its effectiveness decreases very rapidly as the molecular weight increases beyond about 30 kD. We have recently developed a method for protein structure determination that can fully utilize partial NMR data as calculation constraints. The core of the method is a threading algorithm that guarantees to find a globally optimal alignment between a query sequence and a template structure, under distance constraints specified by NMR/NOE data. Our preliminary tests have demonstrated that a small number of NMR/NOE distance restraints can significantly improve threading performance in both fold recognition and threading-alignment accuracy, and can possibly extend threading's scope of applicability from structural homologs to structural analogs. An accurate backbone structure generated by NMR-constrained threading can then provide a significant amount of structural information, equivalent to that provided by the NMR method with many NMR/NOE restraints; and hence can greatly reduce the amount of NMR data typically required for accurate structure determination. Our preliminary study suggests that a small number of NMR/NOE restraints may suffice to determine adequately the all-atom structure when those restraints are incorporated in a procedure combining threading, modeling of loops and sidechains, and molecular dynamics simulation. Potentially, this new technique can expand NMR's capability to larger proteins.

  4. CALCULATION OF ACOUSTIC EFFICIENCY OF PORTABLE ACOUSTIC SCREEN

    Directory of Open Access Journals (Sweden)

    Aleksandr Skvortsov

    2016-03-01

    Full Text Available The research of influence of life environment adverse factors on physical development and health of population is an actual problem of ecology. The aspects of the most actual problems of the modern world, namely environmental industrial noise pollution are considered in the article. Industrial facilities everywhere have noisy equipment. Noise is a significant factors of negative influenceon people and environment. Combined effects of noise and of other physical pollutions on people may cause amplification of their negative impact. If the noise pollution level from the object in a residential area exceeds the permissible levels (MPL, noise protection measures can be initiated. Today, the most common design decisions for noise protection are sound absorbing construction, noise screens and barriers, acousting housings, soundproff cabins. Many of them are popular, others are less known. The article deals with one of the most wide spread means of noise protection – a portable acoustic screen. The aim of the research is to determine the efficiency of portable acoustic screens. It is shown that the installation of such structures can reduce the average value of the sound level. The authors analyzed acoustic screens as device to reduce noise pollution. The authors offer a potable acoustic screen differing from the used easyness, mobility, minimum price and good sound protective properties. Effectiveness, a sound absorption coefficient and sound conductivity coefficient of a portable acoustic screen are evaluated. The descriptions of the algorithm calculations and the combination of technical solutions have practical originality. The results of the research demonstrate the advantages of the proposed solutions for reducing noise levels in the agro-industrial complex.

  5. Acoustic design method of ship's cabin based on geometrical acoustics

    OpenAIRE

    FENG Aijing; WEI Qiang; ZHANG Dahai

    2017-01-01

    In light of the question of how to select the best noise control position and measures in the large noise transmission path of the cabins of a ship, based on the acoustic ray-tracing method in the theory of geometrical acoustics, and by considering the effect of the sound transmission of the bulkhead, this paper proposes the sound line search method. It is used to calculate the sound pressure of a ship's cabin, allowing the sound field distribution of multiple compartments to be simulated. Th...

  6. Knowns and unknowns in metabolomics identified by multidimensional NMR and hybrid MS/NMR methods

    Energy Technology Data Exchange (ETDEWEB)

    Bingol, Kerem; Brüschweiler, Rafael

    2017-02-01

    Metabolomics continues to make rapid progress through the development of new and better methods and their applications to gain insight into the metabolism of a wide range of different biological systems from a systems biology perspective. Customization of NMR databases and search tools allows the faster and more accurate identification of known metabolites, whereas the identification of unknowns, without a need for extensive purification, requires new strategies to integrate NMR with mass spectrometry, cheminformatics, and computational methods. For some applications, the use of covalent and non-covalent attachments in the form of labeled tags or nanoparticles can significantly reduce the complexity of these tasks.

  7. Fast automated protein NMR data collection and assignment by ADAPT-NMR on Bruker spectrometers

    Science.gov (United States)

    Lee, Woonghee; Hu, Kaifeng; Tonelli, Marco; Bahrami, Arash; Neuhardt, Elizabeth; Glass, Karen C.; Markley, John L.

    2013-11-01

    ADAPT-NMR (Assignment-directed Data collection Algorithm utilizing a Probabilistic Toolkit in NMR) supports automated NMR data collection and backbone and side chain assignment for [U-13C, U-15N]-labeled proteins. Given the sequence of the protein and data for the orthogonal 2D 1H-15N and 1H-13C planes, the algorithm automatically directs the collection of tilted plane data from a variety of triple-resonance experiments so as to follow an efficient pathway toward the probabilistic assignment of 1H, 13C, and 15N signals to specific atoms in the covalent structure of the protein. Data collection and assignment calculations continue until the addition of new data no longer improves the assignment score. ADAPT-NMR was first implemented on Varian (Agilent) spectrometers [A. Bahrami, M. Tonelli, S.C. Sahu, K.K. Singarapu, H.R. Eghbalnia, J.L. Markley, PLoS One 7 (2012) e33173]. Because of broader interest in the approach, we present here a version of ADAPT-NMR for Bruker spectrometers. We have developed two AU console programs (ADAPT_ORTHO_run and ADAPT_NMR_run) that run under TOPSPIN Versions 3.0 and higher. To illustrate the performance of the algorithm on a Bruker spectrometer, we tested one protein, chlorella ubiquitin (76 amino acid residues), that had been used with the Varian version: the Bruker and Varian versions achieved the same level of assignment completeness (98% in 20 h). As a more rigorous evaluation of the Bruker version, we tested a larger protein, BRPF1 bromodomain (114 amino acid residues), which yielded an automated assignment completeness of 86% in 55 h. Both experiments were carried out on a 500 MHz Bruker AVANCE III spectrometer equipped with a z-gradient 5 mm TCI probe. ADAPT-NMR is available at http://pine.nmrfam.wisc.edu/ADAPT-NMR in the form of pulse programs, the two AU programs, and instructions for installation and use.

  8. Acoustic sensing from small-size UAVs

    Science.gov (United States)

    Robertson, Dale N.; Pham, Tien; Edge, Harris; Porter, Brian; Shumaker, Justin; Cline, Duane

    2007-04-01

    As part of a research initiative within the US Army Research Laboratory, we investigate acoustic sensing capability from UAVs for remote Intelligence Surveillance and Reconnaissance (ISR) applications. Acoustic sensing from UAVs offers several advantages over acoustic sensing on the ground including: (i) longer detection ranges due to upward refraction and (ii) a single elevated acoustic array (versus multiple acoustic arrays on the ground) can provide a pointing vector to the acoustic source on the ground. However, there are technical challenges with having acoustic sensors on UAVs which involve self generated noise from the platform and the air flow. In this paper, we describe our current work with acoustic sensors on small UAV platforms and present preliminary processing results from a recent field experiment.

  9. Acoustic remote sensing of ocean flows

    Digital Repository Service at National Institute of Oceanography (India)

    Joseph, A.; Desa, E.

    Acoustic techniques have become powerful tools for measurement of ocean circulation mainly because of the ability of acoustic signals to travel long distances in water, and the inherently non-invasive nature of measurement. The satellite remote...

  10. Acoustic evaluation of wood quality in standing trees. Part I, Acoustic wave behavior

    Science.gov (United States)

    Xiping Wang; Robert J. Ross; Peter Carter

    2007-01-01

    Acoustic wave velocities in standing trees or live softwood species were measured by the time-of-flight (TOF) method. Tree velocities were compared with acoustic velocities measured in corresponding butt logs through a resonance acoustic method. The experimental data showed a skewed relationship between tree and log acoustic measurements. For most trees tested,...

  11. Software-based acoustical measurements

    CERN Document Server

    Miyara, Federico

    2017-01-01

    This textbook provides a detailed introduction to the use of software in combination with simple and economical hardware (a sound level meter with calibrated AC output and a digital recording system) to obtain sophisticated measurements usually requiring expensive equipment. It emphasizes the use of free, open source, and multiplatform software. Many commercial acoustical measurement systems use software algorithms as an integral component; however the methods are not disclosed. This book enables the reader to develop useful algorithms and provides insight into the use of digital audio editing tools to document features in the signal. Topics covered include acoustical measurement principles, in-depth critical study of uncertainty applied to acoustical measurements, digital signal processing from the basics, and metrologically-oriented spectral and statistical analysis of signals. The student will gain a deep understanding of the use of software for measurement purposes; the ability to implement software-based...

  12. Acoustic energy propagation around railways

    Science.gov (United States)

    Cizkova, Petra

    2017-09-01

    The article deals with the issues of acoustic energy propagation around railways. The research subject was noise emission spreading into the surroundings during the passage of trains over a directly travelled steel bridge construction. Noise emissions were measured using direct measurements in the field. The measurements were performed in two measurement profiles. The noise exposures A LAE measured near the steel bridge construction were compared against the noise exposures A LAE captured on an open track. From the difference of these data, the noise level of the steel bridge structure was determined. Part of the research was to evaluate the effect of the reconstruction of the railway track superstructure on the acoustic situation in the given section of the railway track. The article describes the methodology of measurements, including the processing and evaluation of measured data. The article points out the noise levels of the steel bridge construction and assesses changes in the acoustic situation after the reconstruction.

  13. Acoustic multivariate condition monitoring - AMCM

    Energy Technology Data Exchange (ETDEWEB)

    Rosenhave, P.E. [Vestfold College, Maritime Dept., Toensberg (Norway)

    1997-12-31

    In Norway, Vestfold College, Maritime Department presents new opportunities for non-invasive, on- or off-line acoustic monitoring of rotating machinery such as off-shore pumps and diesel engines. New developments within acoustic sensor technology coupled with chemometric data analysis of complex signals now allow condition monitoring of hitherto unavailable flexibility and diagnostic specificity. Chemometrics paired with existing knowledge yields a new and powerful tool for condition monitoring. By the use of multivariate techniques and acoustics it is possible to quantify wear and tear as well as predict the performance of working components in complex machinery. This presentation describes the AMCM method and one result of a feasibility study conducted onboard the LPG/C `Norgas Mariner` owned by Norwegian Gas Carriers as (NGC), Oslo. (orig.) 6 refs.

  14. Direct Comparison of 19F qNMR and 1H qNMR by Characterizing Atorvastatin Calcium Content

    Directory of Open Access Journals (Sweden)

    Yang Liu

    2016-01-01

    Full Text Available Quantitative nuclear magnetic resonance (qNMR is a powerful tool in measuring drug content because of its high speed, sensitivity, and precision. Most of the reports were based on proton qNMR (1H qNMR and only a few fluorine qNMR (19F qNMR were reported. No research has been conducted to directly compare the advantage and disadvantage between these two methods. In the present study, both 19F and 1H qNMR were performed to characterize the content of atorvastatin calcium with the same internal standard. Linearity, precision, and results from two methods were compared. Results showed that 19F qNMR has similar precision and sensitivity to 1H qNMR. Both methods generate similar results compared to mass balance method. Major advantage from 19F qNMR is that the analyte signal is with less or no interference from impurities. 19F qNMR is an excellent approach to quantify fluorine-containing analytes.

  15. Direct Comparison of 19F qNMR and 1H qNMR by Characterizing Atorvastatin Calcium Content

    Science.gov (United States)

    Liu, Yang; Liu, Zhaoxia; Yang, Huaxin

    2016-01-01

    Quantitative nuclear magnetic resonance (qNMR) is a powerful tool in measuring drug content because of its high speed, sensitivity, and precision. Most of the reports were based on proton qNMR (1H qNMR) and only a few fluorine qNMR (19F qNMR) were reported. No research has been conducted to directly compare the advantage and disadvantage between these two methods. In the present study, both 19F and 1H qNMR were performed to characterize the content of atorvastatin calcium with the same internal standard. Linearity, precision, and results from two methods were compared. Results showed that 19F qNMR has similar precision and sensitivity to 1H qNMR. Both methods generate similar results compared to mass balance method. Major advantage from 19F qNMR is that the analyte signal is with less or no interference from impurities. 19F qNMR is an excellent approach to quantify fluorine-containing analytes. PMID:27688925

  16. Acoustic behaviors of unsaturated soils

    Science.gov (United States)

    Lu, Z.

    2011-12-01

    Soils are unconsolidated granular materials, consisting of solid particles, water and air. Their mechanical and dynamic behaviors are determined by the discrete nature of the media as well as external and inter-particle forces. For unsaturated soils, two factors significantly affect soils acoustic/seismic responses: external pressure and internal water potential/matric suction. In triaxial cell tests, unsaturated soils were subjected to predefined stress paths to undergo stages of normal consolidation, unload-reload cycles, and failure. The stress deformation curve and stress-P-wave velocity were measured and compared. The study revealed that soil's dynamic response to external pressure are similar to those of the load-deformation behaviors and demonstrated that acoustic velocity can be used to monitor the state of stress of soils. In a long term field soil survey, the P-wave velocities were found to be correlated with water potential as expressed as a power-law relationship. The above phenomena can be understood by using the Terzaghi' s the principle of effective stress. The measured results were in good agreement with Brutsaert theory. The effective stress concept can also be applied to explain the observations in a soil pipe flow study in which soil internal erosion processes were monitored and interpreted by the temporal evolution of the P-wave velocity. In addition to above linear acoustic behaviors, soils, like other earth materials, exhibit astonishing non-classical nonlinear behaviors such as end-point memory, hysteresis, strain -dependent shear modulus, resonant frequency shift, and phase shift, harmonics generation, etc. A nonlinear acoustic study of a soil as a function of water content showed that the nonlinear acoustic parameter are much sensitive to the variations of soil water content than that of the acoustic velocity.

  17. Absorption boundary conditions for geomertical acoustics

    DEFF Research Database (Denmark)

    Jeong, Cheol-Ho

    2012-01-01

    Defining accurate acoustical boundary conditions is of crucial importance for room acoustic simulations. In predicting sound fields using phased geometrical acoustics methods, the absorption coefficients or surface impedances of the boundary surfaces can be used, but no guideline has been developed...... solutions. Two rectangular rooms with uniform and non-uniform absorption distributions are tested. It is concluded that the impedance and random incidence absorption boundary conditions produce reasonable results with some exceptions at low frequencies for acoustically soft materials....

  18. Direct 13C NMR Detection in HPLC Hyphenation Mode

    DEFF Research Database (Denmark)

    Wubshet, Sileshi Gizachew; Johansen, Kenneth; Nyberg, Nils

    2012-01-01

    is indubitable in simplifying structural elucidations. In the current study, we demonstrated direct (13)C NMR detection of triterpenoids from a Ganoderma lucidum extract in hyphenation mode. The combined advantage of a cryogenically cooled probe, miniaturization, and multiple trapping enabled the first reported......Solid phase extraction (SPE) was introduced as a crucial step in the HPLC-SPE-NMR technique to enable online analyte enrichment from which proton-detected NMR experiments on submicrogram amounts from complex mixtures were possible. However, the significance of direct-detected (13)C NMR experiments...... application of HPLC-SPE-NMR analysis using direct-detected (13)C NMR spectra. HPLC column loading, accumulative SPE trappings, and the effect of different elution solvents were evaluated and optimized. A column loading of approximately 600 mug of a prefractionated triterpenoid mixture, six trappings...

  19. (S)Pinning down protein interactions by NMR

    DEFF Research Database (Denmark)

    Teilum, Kaare; Kunze, Micha Ben Achim; Erlendsson, Simon

    2017-01-01

    all types of protein reactions, which can span orders of magnitudes in affinities, reaction rates and lifetimes of states. As the more versatile technique, solution NMR spectroscopy offers a remarkable catalogue of methods that can be successfully applied to the quantitative as well as qualitative...... descriptions of protein interactions. In this review we provide an easy-access approach to NMR for the non-NMR specialist and describe how and when solution state NMR spectroscopy is the method of choice for addressing protein ligand interaction. We describe very briefly the theoretical background...... and illustrate simple protein-ligand interactions and as well as typical strategies for measuring binding constants using NMR spectroscopy. Finally, this review provides examples of caveats of the method as well as the options to improve the outcome of an NMR analysis of a protein interaction reaction...

  20. Phase conjugation of acoustic beams

    Science.gov (United States)

    Bunkin, F. V.; Vlasov, D. V.; Kravtsov, Iu. A.

    The paper presents a classification of methods for the phase conjugation (PC) of wave fields of various physical natures on the basis of such nonliner interactions as stimulated scattering, and three- and four-wave interactions. Among the latter, attention is given to holographic (volume and surface) and parametric PC schemes, permitting PC with amplification. The possibility of developing phase-conjugated devices using acoustic PC devices on the basis of various nonlinear effects is considered. Experimental results pertaining to the PC of sound fields are presented, and possible applications of acoustic PC devices are indicated.

  1. Acoustics of the Vowel - Preliminaries

    OpenAIRE

    Maurer, Dieter

    2016-01-01

    It seems as if the fundamentals of how we produce vowels and how they are acoustically represented have been clarified: we phonate and articulate. Using our vocal chords, we produce a vocal sound or noise which is then shaped into a specific vowel sound by the resonances of the pharyngeal, oral, and nasal cavities, that is, the vocal tract. Accordingly, the acoustic description of vowels relates to vowel-specific patterns of relative energy maxima in the sound spectra, known as patterns of fo...

  2. Gas sensing with acoustic devices

    Energy Technology Data Exchange (ETDEWEB)

    Martin, S.J.; Frye, G.C. [Sandia National Labs., Albuquerque, NM (United States); Spates, J.J. [Ktech Corp., Albuquerque, NM (United States); Butler, M.A. [Sandia National Labs., Albuquerque, NM (United States)

    1996-12-31

    A survey is made of acoustic devices that are suitable as gas and vapor sensors. This survey focuses on attributes such as operating frequency, mass sensitivity, quality factor (Q), and their ability to be fabricated on a semiconductor substrate to allow integration with electronic circuitry. The treatment of the device surface with chemically-sensitive films to detect species of interest is discussed. Strategies for improving discrimination are described, including sensor arrays and species concentration and separation schemes. The advantages and disadvantages of integrating sensors with microelectronics are considered, along with the effect on sensitivity of scaling acoustic gas sensors to smaller size.

  3. Acoustic design by topology optimization

    DEFF Research Database (Denmark)

    Dühring, Maria Bayard; Jensen, Jakob Søndergaard; Sigmund, Ole

    2008-01-01

    To bring down noise levels in human surroundings is an important issue and a method to reduce noise by means of topology optimization is presented here. The acoustic field is modeled by Helmholtz equation and the topology optimization method is based on continuous material interpolation functions...... in the density and bulk modulus. The objective function is the squared sound pressure amplitude. First, room acoustic problems are considered and it is shown that the sound level can be reduced in a certain part of the room by an optimized distribution of reflecting material in a design domain along the ceiling...

  4. Acoustic-gravity nonlinear structures

    Directory of Open Access Journals (Sweden)

    D. Jovanović

    2002-01-01

    Full Text Available A catalogue of nonlinear vortex structures associated with acoustic-gravity perturbations in the Earth's atmosphere is presented. Besides the previously known Kelvin-Stewart cat's eyes, dipolar and tripolar structures, new solutions having the form of a row of counter-rotating vortices, and several weakly two-dimensional vortex chains are given. The existence conditions for these nonlinear structures are discussed with respect to the presence of inhomogeneities of the shear flows. The mode-coupling mechanism for the nonlinear generation of shear flows in the presence of linearly unstable acoustic-gravity waves, possibly also leading to intermittency and chaos, is presented.

  5. Physical foundations of technical acoustics

    CERN Document Server

    Malecki, I

    1969-01-01

    Physical Foundations of Technical Acoustics discusses theoretical foundations of acoustical engineering. It is not so much a technical compendium as a systematic statement of physical laws so conceived that technologists might find in it all the information they need to become acquainted with the physical meaning and mathematical expression of phenomena they encounter in their work. To facilitate the acquirement of notions, which lie beyond a layman's grasp, the plan of narration adopted consists in beginning with the simplest idealized cases and then gradually moving on to the truest possibl

  6. Rovibrational and temperature effects in theoretical studies of NMR parameters

    DEFF Research Database (Denmark)

    Faber, Rasmus; Kaminsky, Jakub; Sauer, Stephan P. A.

    2016-01-01

    The demand for high precision calculations of NMR shieldings (or their related values, chemical shifts δ) and spin-spin coupling constants facilitating and supporting detailed interpretations of NMR spectra increases hand in hand with the development of computational techniques and hardware...... resources. Highly sophisticated calculations including even relativistic effects are nowadays possible for these properties. However, NMR parameters depend not only on molecular structure and environment but also on molecular flexibility and temperature and the apparent success of theoretical predictions...

  7. Fluid-Rock Characterization and Interactions in NMR Well Logging

    Energy Technology Data Exchange (ETDEWEB)

    Hirasaki, George J.; Mohanty, Kishore K.

    2003-02-10

    The objective of this project was to characterize the fluid properties and fluid-rock interactions that are needed for formation evaluation by NMR well logging. The advances made in the understanding of NMR fluid properties are summarized in a chapter written for an AAPG book on NMR well logging. This includes live oils, viscous oils, natural gas mixtures, and the relation between relaxation time and diffusivity.

  8. Nuclear Magnetic Resonance Logging While Drilling (NMR-LWD)

    OpenAIRE

    Blanz, Martin; Kruspe, Thomas; Thern, Holger Frank; Kurz, Gerhard Alfons

    2015-01-01

    NMR T2 distribution measurement is our chosen everyday method for NMR logging while drilling oil and gas wells. This method yields straightforward preparation and execution of the job as well as a normally easy interpretation of the measured data. For instance, gas and light oil discrimination against water is feasible by direct observation of the T2 distribution. A condition for this measurement method is a NMR logging tool that hardly moves while drilling and in addition uses a small static...

  9. Application of holography in jet acoustic studies

    Indian Academy of Sciences (India)

    Source strength distribution on a jet boundary was obtained from measurements using the principle of acoustic holography. Measurements were conducted in an open field. Measurement of acoustic pressure on a cylindrical twodimensional contour located close to the vibrating jet boundary was used to obtain the acoustic ...

  10. Electromagnetic energy harvester for harvesting acoustic energy

    Indian Academy of Sciences (India)

    Farid U Khan

    giadis et al [10] respectively. Moreover, acoustical noise is also present in abundance in the surroundings [11–15]. Converting ambient acoustical noise with an acoustic energy (AEH) into a useful electrical power is most appropriate for applications like health monitoring of vehicles, machineries, buildings and bridges.

  11. Tips: Improving Acoustics for Music Teaching.

    Science.gov (United States)

    Geerdes, Harold P.

    A specifications pamphlet offers methods, ideas, and suggestions on how music educators can upgrade their existing music facilities or design new ones correctly. Guidelines address room acoustic fundamentals, how to critique a music room, hints on upgrading acoustic weaknesses, and general tips to follow when trying to maximize acoustics when…

  12. Outdoor Acoustics as a General Discipline

    DEFF Research Database (Denmark)

    Rasmussen, Karsten Bo

    1999-01-01

    A tutorial paper exploring the characteristics of sound outdoors. Outdoor acoustics is contrasted to room acoustics. A number of important aspects of outdoor acoustics are exemplified and theoretical approaches are outlined. These are influence of ground impedance, influence of weather, screening...

  13. Predicting and auralizing acoustics in classrooms

    DEFF Research Database (Denmark)

    Christensen, Claus Lynge

    2005-01-01

    Although classrooms have fairly simple geometries, this type of room is known to cause problems when trying to predict their acoustics using room acoustics computer modeling. Some typical features from a room acoustics point of view are: Parallel walls, low ceilings (the rooms are flat), uneven...

  14. Location of an acoustic window in dolphins.

    Science.gov (United States)

    Popov, V V; Supin, A Y

    1990-01-15

    Auditory brainstem responses (ABR) to sound clicks from sources in different positions were recorded in dolphins Inia geoffrensis. The position of the acoustic window was determined by measurement of acoustic delays. The acoustic window was found to lie close to the auditory meatus and the bulla rather than on the lower jaw.

  15. Measuring ship acoustic signatures against mine threat

    NARCIS (Netherlands)

    Jong, C.A.F. de; Quesson, B.A.J.; Ainslie, M.A.; Vermeulen, R.C.N.

    2012-01-01

    The NATO standard ‘AMP-15’ [1] provides procedures for the measurement and reporting of the acoustic signature of ships and for the establishment of acoustic signature goals to counter the naval mine threat. Measurements are carried out at dedicated shallow water acoustic ranges. Measurements

  16. Aero-acoustic Computations of Wind Turbines

    DEFF Research Database (Denmark)

    Shen, Wen Zhong; Michelsen, Jess; Sørensen, Jens Nørkær

    2002-01-01

    A numerical algorithm for acoustic noise generation is extended to 3D flows. The approach involves two parts comprising a viscous incompressible flow part and an inviscid acoustic part. In order to simulate noise generated from a wind turbine, the incompressible and acoustic equations are written...

  17. Acoustic reflection from the boundary of anisotropic ...

    Indian Academy of Sciences (India)

    Reflection and refraction of plane harmonic acoustic waves are studied at a plane boundary between anisotropic thermoviscoelastic solid and a non-viscous fluid. At this fluid-solid interface, an incident acoustic wave through the fluid reflects back as an attenuated acoustic wave and refracts as four attenuating waves into ...

  18. Metal glasses in microscopic scale: NMR studies

    Energy Technology Data Exchange (ETDEWEB)

    Tompa, K.; Bakonyi, I.; Varga, L. (Hungarian Academy of Sciences, Budapest. Central Research Inst. for Physics)

    1984-01-01

    A variety of amorphous metallic glasses was prepared by electrolysis, chemical reduction or fast cooling. Local orders, structural symmetry and topology were studied by means of NMR. Dipole-dipole and quadrupole interactions were analysed in Ni-P, Ni-Cu-P and Ni-B metallic glasses containing sup(31)P or sup(11)B nuclei. Experimentally determined signal widths were compared with the calculated values of model structures. The good agreement indicates structural identities of the nickel-containing glasses and the assumed models.

  19. Multiple-quantum NMR in solids

    Energy Technology Data Exchange (ETDEWEB)

    Yen, Yu-Sze [Univ. of California, Berkeley, CA (United States)

    1982-11-01

    Time domain multiple-quantum (MQ) nuclear magnetic resonance (NMR) spectroscopy is a powerful tool for spectral simplification and for providing new information on molecular dynamics. In this thesis, applications of MQ NMR are presented and show distinctly the advantages of this method over the conventional single-quantum NMR. Chapter 1 introduces the spin Hamiltonians, the density matrix formalism and some basic concepts of MQ NMR spectroscopy. In chapter 2, 14N double-quantum coherence is observed with high sensitivity in isotropic solution, using only the magnetization of bound protons. Spin echoes are used to obtain the homogeneous double-quantum spectrum and to suppress a large H2O solvent signal. Chapter 3 resolves the main difficulty in observing high MQ transitions in solids. Due to the profusion of spin transitions in a solid, individual lines are unresolved. Excitation and detection of high quantum transitions by normal schemes are thus difficult. To ensure that overlapping lines add constructively and thereby to enhance sensitivity, time-reversal pulse sequences are used to generate all lines in phase. Up to 22-quantum 1H absorption in solid adamantane is observed. A time dependence study shows an increase in spin correlations as the excitation time increased. In chapter 4, a statistical theory of MQ second moments is developed for coupled spins of spin I = 1/2. The model reveals that the ratio of the average dipolar coupling to the rms value largely determines the dependence of second moments on the number of quanta. The results of this model are checked against computer-calculated and experimental second moments, and show good agreement. A simple scheme is proposed in chapter 5 for sensitivity improvement in a MQ experiment. The scheme involves acquiring all of the signal energy available in the detection period by applying pulsed spinlocking and sampling between pulses. Using this technique on polycrystalline

  20. Touch NMR: An NMR Data Processing Application for the iPad

    Science.gov (United States)

    Li, Qiyue; Chen, Zhiwei; Yan, Zhiping; Wang, Cheng; Chen, Zhong

    2014-01-01

    Nuclear magnetic resonance (NMR) spectroscopy has become one of the most powerful technologies to aid research in numerous scientific disciplines. With the development of consumer electronics, mobile devices have played increasingly important roles in our daily life. However, there is currently no application available for mobile devices able to…

  1. Extracting protein dynamics information from overlapped NMR signals using relaxation dispersion difference NMR spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Konuma, Tsuyoshi [Icahn School of Medicine at Mount Sinai, Department of Structural and Chemical Biology (United States); Harada, Erisa [Suntory Foundation for Life Sciences, Bioorganic Research Institute (Japan); Sugase, Kenji, E-mail: sugase@sunbor.or.jp, E-mail: sugase@moleng.kyoto-u.ac.jp [Kyoto University, Department of Molecular Engineering, Graduate School of Engineering (Japan)

    2015-12-15

    Protein dynamics plays important roles in many biological events, such as ligand binding and enzyme reactions. NMR is mostly used for investigating such protein dynamics in a site-specific manner. Recently, NMR has been actively applied to large proteins and intrinsically disordered proteins, which are attractive research targets. However, signal overlap, which is often observed for such proteins, hampers accurate analysis of NMR data. In this study, we have developed a new methodology called relaxation dispersion difference that can extract conformational exchange parameters from overlapped NMR signals measured using relaxation dispersion spectroscopy. In relaxation dispersion measurements, the signal intensities of fluctuating residues vary according to the Carr-Purcell-Meiboon-Gill pulsing interval, whereas those of non-fluctuating residues are constant. Therefore, subtraction of each relaxation dispersion spectrum from that with the highest signal intensities, measured at the shortest pulsing interval, leaves only the signals of the fluctuating residues. This is the principle of the relaxation dispersion difference method. This new method enabled us to extract exchange parameters from overlapped signals of heme oxygenase-1, which is a relatively large protein. The results indicate that the structural flexibility of a kink in the heme-binding site is important for efficient heme binding. Relaxation dispersion difference requires neither selectively labeled samples nor modification of pulse programs; thus it will have wide applications in protein dynamics analysis.

  2. 31 P-NMR, 77 Se-NMR and mass spectral studies on some ...

    African Journals Online (AJOL)

    A series of aminophosphines were prepared by controlled condensation reaction between PCl3 or PhPCl2 and amines, and they were converted into the corresponding chalcogenides. 31P-NMR and mass spectral data were collected for characterization of these asymmetrically substituted phosphines, and in addition, ...

  3. NMR structural studies of oligosaccharides and other natural products

    OpenAIRE

    Kjærulff, Louise; Gotfredsen, Charlotte Held

    2014-01-01

    NMR spektroskopi er et af de vigtigste værktøjer til analyse og strukturopklaring af kemiske stoffer og bruges inden for mange forskellige forskningsområder. Denne afhandling omhandler NMR-spektroskopisk strukturanalyse af små molekyler i vandig eller organisk opløsning, både i forhold til metodeudvikling og strukturopklaring vha. NMR spektroskopi. HMBC+ er et nyudviklet pseudo-3D NMR eksperiment til måling af n+1JHH homonukleare koblingskonstanter over 3-4 bindinger i små molekyler, observer...

  4. Optimization and practical implementation of ultrafast 2D NMR experiments

    Energy Technology Data Exchange (ETDEWEB)

    Queiroz Junior, Luiz H. K., E-mail: professorkeng@gmail.com [Universidade Federal de Sao Carlos (UFSC), SP (Brazil). Departamento de Quimica; Universidade Federal de Goias (UFGO), Goiania, GO (Brazil). Inst. de Quimica; Ferreira, Antonio G. [Universidade Federal de Sao Carlos (UFSC), SP (Brazil). Departamento de Quimica; Giraudeau, Patrick [Universite de Nantes (France). CNRS, Chimie et Interdisciplinarite: Synthese, Analyse, Modelisation

    2013-09-01

    Ultrafast 2D NMR is a powerful methodology that allows recording of a 2D NMR spectrum in a fraction of second. However, due to the numerous non-conventional parameters involved in this methodology its implementation is no trivial task. Here, an optimized experimental protocol is carefully described to ensure efficient implementation of ultrafast NMR. The ultrafast spectra resulting from this implementation are presented based on the example of two widely used 2D NMR experiments, COSY and HSQC, obtained in 0.2 s and 41 s, respectively. (author)

  5. Evaluation of fast 2D NMR for metabolomics.

    Science.gov (United States)

    Guennec, Adrien Le; Giraudeau, Patrick; Caldarelli, Stefano

    2014-06-17

    Two-dimensional nuclear magnetic resonance (2D NMR) is increasingly explored as a tool for metabolomics because of its superior resolution compared to one-dimensional NMR (1D NMR). However, 2D NMR is characterized by longer acquisition times, which makes it less suitable for high-throughput studies. In this Article, we evaluated two methods for the acceleration of nD NMR, ultrafast (UF) and nonuniform sampling (NUS), in the context of metabolomics. To this end, model samples mimicking the metabolic profile variations in serum from subjects affected by colorectal cancer and controls were analyzed by 1D (1)H NMR along with conventional and accelerated DQF-COSY and HSQC. A statistical analysis (OPLS-DA) yielded similar results for the group separation with all techniques, but biomarker identification from 2D spectra was substantially enhanced, both in terms of number of molecules and easiness of assignment. Most interestingly, fast 2D NMR techniques lead to similar results as conventional 2D NMR, opening the way for high-throughput metabolomics studies using 2D NMR.

  6. Method development in quantitative NMR towards metrologically traceable organic certified reference materials used as 31P qNMR standards

    OpenAIRE

    Weber, Michael; Hellriegel, Christine; Rueck, Alexander; Wuethrich, Juerg; Jenks, Peter; Obkircher, Markus

    2014-01-01

    Quantitative nuclear magnetic resonance (qNMR) spectroscopy is employed by an increasing number of analytical and industrial laboratories for the assignment of content and quantitative determination of impurities. Within the last few years, it was demonstrated that 1H qNMR can be performed with high accuracy leading to measurement uncertainties below 1?% relative. It was even demonstrated that the combination of 1H qNMR with metrological weighing can lead to measurement uncertainties below 0....

  7. Assessment of Bone Microstructural Changes by NMR

    Science.gov (United States)

    Ni, Qingwen; Wang, Xiaodu

    2008-03-01

    Previous studies have shown that age related increases in bone porosity without significant changes in bone mineral density (BMD) (without bone microstructural information) result in a decrease in bone strength. Bone fracture toughness is also significantly correlated to changes in porosity, microarchitecture, collagen integrity, microdamage, and water distribution, all of which are measures of bone quality. Unfortunately, current technology does not allow the non-destructive and non-invasive detection of bone water distribution or other measures of bone quality including microporosity. On the other hand, Nuclear Magnetic Resonance (NMR) proton spin-spin (T2) relaxation time measurements and computational analytical method have been used to determine microstructural characteristics of various types of fluid filled porous materials. The study in here is to demonstrate that non-destructive and non-invasive NMR proton spin-spin (T2) relaxation techniques has been developed and applied to quantify the porosity, pore size distribution and water distribution in human cortical bone. This new bone microstructural information can then be used as descriptions of bone quality and, along or in combination with existing method (BMD) to more accurately assess bone fracture risk, and the results could help doctors and researchers to detect osteoporosis and other conditions related to weak bones in persons.

  8. NMR-based diffusion pore imaging.

    Science.gov (United States)

    Laun, Frederik Bernd; Kuder, Tristan Anselm; Wetscherek, Andreas; Stieltjes, Bram; Semmler, Wolfhard

    2012-08-01

    Nuclear magnetic resonance (NMR) diffusion experiments offer a unique opportunity to study boundaries restricting the diffusion process. In a recent Letter [Phys. Rev. Lett. 107, 048102 (2011)], we introduced the idea and concept that such diffusion experiments can be interpreted as NMR imaging experiments. Consequently, images of closed pores, in which the spins diffuse, can be acquired. In the work presented here, an in-depth description of the diffusion pore imaging technique is provided. Image artifacts due to gradient profiles of finite duration, field inhomogeneities, and surface relaxation are considered. Gradients of finite duration lead to image blurring and edge enhancement artifacts. Field inhomogeneities have benign effects on diffusion pore images, and surface relaxation can lead to a shrinkage and shift of the pore image. The relation between boundary structure and the imaginary part of the diffusion weighted signal is analyzed, and it is shown that information on pore coherence can be obtained without the need to measure the phase of the diffusion weighted signal. Moreover, it is shown that quite arbitrary gradient profiles can be used for diffusion pore imaging. The matrices required for numerical calculations are stated and provided as supplemental material.

  9. NMR assessment on bone simulated under microgravity

    Science.gov (United States)

    Ni, Q.; Qin, Y.

    Introduction Microgravity-induced bone loss has been suggested to be similar to disuse-osteoporosis on Earth which constitutes a challenging public health problem No current non-destructive method can provide the microstructural changes in bone particularly on cortical bone Recently the authors have applied low field nuclear magnetic resonance NMR spin-spin relaxation technique and computational analysis method to determine the porosity pore size distribution and microdamage of cortical bone 1-3 The studies by the authors have shown that this technology can be used to characterize microstructural changes as well as bone water distribution bound and mobile water changes of weightless treated simulating a microgravity condition turkey and mouse cortical bone We further determinate that the NMR spin-spin relaxation time T 2 spectrum derived parameters can be used as descriptions of bone quality e g matrix water distribution and porosity size distributions and alone or in combination with current techniques bone mineral density measurements more accurately predict bone mechanical properties Methods underline Bone sample preparation Two kinds of animal samples were collected and prepared for designed experiments from SUNY Cortical bones of the mid-diaphyses of the ulnae of 1-year-old male turkeys were dissected from freshly slaughtered animals Eight samples were categorized from normal or control and four samples were 4-week disuse treated by functionally isolated osteotomies disuse A total of 12

  10. Acoustic cues to Nehiyawewin constituency

    Science.gov (United States)

    Cook, Clare; Muehlbauer, Jeff

    2005-04-01

    This study examines how speakers use acoustic cues, e.g., pitch and pausing, to establish syntactic and semantic constituents in Nehiyawewin, an Algonquian language. Two Nehiyawewin speakers autobiographies, which have been recorded, transcribed, and translated by H. C. Wolfart in collaboration with a native speaker of Nehiyawewin, provide natural-speech data for the study. Since it is difficult for a non-native-speaker to reliably distinguish Nehiyawewin constituents, an intermediary is needed. The transcription provides this intermediary through punctuation marks (commas, semi-colons, em-dashes, periods), which have been shown to consistently mark constituency structure [Nunberg, CSLI 1990]. The acoustic cues are thus mapped onto the punctuated constituents, and then similar constituents are compared to see what acoustic cues they share. Preliminarily, the clearest acoustic signal to a constituent boundary is a pitch drop preceding the boundary and/or a pitch reset on the syllable following the boundary. Further, constituent boundaries marked by a period consistently end on a low pitch, are followed by a pitch reset of 30-90 Hz and have an average pause of 1.9 seconds. I also discuss cross-speaker cues, and prosodic cues that do not correlate to punctuation, with implications for the transcriptional view of orthography [Marckwardt, Oxford 1942].

  11. Acoustical coupling of lizard eardrums

    DEFF Research Database (Denmark)

    Christensen-Dalsgaard, Jakob; Manley, Geoffrey A

    2008-01-01

    Lizard ears are clear examples of two-input pressure-difference receivers, with up to 40-dB differences in eardrum vibration amplitude in response to ipsi- and contralateral stimulus directions. The directionality is created by acoustical coupling of the eardrums and interaction of the direct and...

  12. Topology optimization for acoustic problems

    DEFF Research Database (Denmark)

    Dühring, Maria Bayard

    2006-01-01

    In this paper a method to control acoustic properties in a room with topology optimization is presented. It is shown how the squared sound pressure amplitude in a certain part of a room can be minimized by distribution of material in a design domain along the ceiling in 2D and 3D. Nice 0-1 designs...

  13. Longitudinal bulk acoustic mass sensor

    DEFF Research Database (Denmark)

    Hales, Jan Harry; Teva, Jordi; Boisen, Anja

    2009-01-01

    A polycrystalline silicon longitudinal bulk acoustic cantilever is fabricated and operated in air at 51 MHz. A mass sensitivity of 100 Hz/fg (1 fg=10(-15) g) is obtained from the preliminary experiments where a minute mass is deposited on the device by means of focused ion beam. The total noise...

  14. Pillar-type acoustic metasurface

    DEFF Research Database (Denmark)

    Jin, Yabin; Bonello, Bernard; Moiseyenko, Rayisa

    2017-01-01

    We theoretically investigate acoustic metasurfaces consisting of either a single pillar or a line of identical pillars on a thin plate, and we report on the dependence on the geometrical parameters of both the monopolar compressional and dipolar bending modes. We show that for specific dimensions...

  15. Satellite and acoustic tracking device

    KAUST Repository

    Berumen, Michael L.

    2014-02-20

    The present invention relates a method and device for tracking movements of marine animals or objects in large bodies of water and across significant distances. The method and device can track an acoustic transmitter attached to an animal or object beneath the ocean surface by employing an unmanned surface vessel equipped with a hydrophone array and GPS receiver.

  16. Acoustical Modifications for the Classroom.

    Science.gov (United States)

    Crandell, Carl C.; Smaldino, Joseph J.

    1999-01-01

    This article reviews procedures for evaluating, measuring, and modifying noise and reverberation levels in the classroom environment. Recommendations include: relocating children away from high noise sources, such as fans, air conditioners, heating ducts, and faulty lighting fixtures, using sound-absorbing materials, using acoustical ceiling tile…

  17. Acoustic backscatter from turbulent microstructure

    Energy Technology Data Exchange (ETDEWEB)

    Seim, H.E.; Gregg, M.C.; Miyamoto, R.T. [Univ. of Washington, Seattle, WA (United States)

    1995-04-01

    Acoustic backscatter has produced spectacular images of internal ocean processes for nearly two decades, but interpretation of the images remains ambiguous because several mechanisms can generate measurable backscatter. The authors present what is thought to be the first simultaneous measurements of calibrated acoustic returns and turbulent microstructure, collected in a set of 20-m-tall billows. The observations are from Admiralty Inlet, a salt-stratified tidal channel near Puget Sound. Scattering due to turbulent microstructure alone is strong enough to explain the measured backscatter at specific sites within the billows. Existing formulations underestimate the strength of acoustic backscatter from turbulent microstructure. Due to a misinterpretation of the high-wavenumber temperature spectrum, some previous formulations underestimate the differential scattering cross section (sigma) when scattering from the viscous-convective subrange. Also, the influence of salinity on refractive-index fluctuations can be as large as or greater than that of temperature when the density stratification is dominated by salinity. Using temperature alone to estimate sigma in coastal and estuarine waters may lead to significant underestimates. A simple formulation is derived that takes these two factors into account. Because of high ambient scattering from zooplankton in Admiralty Inlet, the acoustic data are conditionally sampled along modeled profiler trajectories to avoid using bulk statistics.

  18. Acoustic Liner for Turbomachinery Applications

    Science.gov (United States)

    Huff, Dennis L.; Sutliff, Daniel L.; Jones, Michael G.; Hebsur, Mohan G.

    2010-01-01

    The purpose of this innovation is to reduce aircraft noise in the communities surrounding airports by significantly attenuating the noise generated by the turbomachinery, and enhancing safety by providing a containment barrier for a blade failure. Acoustic liners are used in today's turbofan engines to reduce noise. The amount of noise reduction from an acoustic liner is a function of the treatment area, the liner design, and the material properties, and limited by the constraints of the nacelle or casement design. It is desirable to increase the effective area of the acoustic treatment to increase noise suppression. Modern turbofan engines use wide-chord rotor blades, which means there is considerable treatment area available over the rotor tip. Turbofan engines require containment over the rotors for protection from blade failure. Traditional methods use a material wrap such as Kevlar integrated with rub strips and sometimes metal layers (sandwiches). It is possible to substitute the soft rub-strip material with an open-cell metallic foam that provides noise-reduction benefits and a sacrificial material in the first layer of the containment system. An open-cell foam was evaluated that behaves like a bulk acoustic liner, serves as a tip rub strip, and can be integrated with a rotor containment system. Foams can be integrated with the fan-containment system to provide sufficient safety margins and increased noise attenuation. The major innovation is the integration of the foam with the containment.

  19. Acoustic correlates of Georgian ejectives

    Science.gov (United States)

    Wysocki, Tamra M.

    2002-05-01

    In this paper we present results from acoustic analysis of Georgian ejectives. Georgian, a language of the Kartvelian (South Caucasian) family, has a three-way opposition for voiced, voiceless aspirated and ejective stops. There have not been many acoustic studies of ejectives; those studies that discuss ejectives, such as by Lindau [J. Phonetics 12, 147-155 (1984)], report cross-linguistic variation in timing between oral and glottal releases and the onset of a following vowel. In this paper we investigate acoustic correlates of Georgian ejectives and examine how these correlates are realized in two-member ejective clusters. Additionally, correlates of Georgian ejectives are compared to findings from previous studies and discussed in relation to cross-linguistic tendencies and variation. Data consist of field recordings of three native Georgian speakers producing single ejectives and ejective clusters in word-initial and word-medial (intervocalic) positions at a normal rate of speech. Acoustic analysis was completed using spectrograms and waveforms. Results indicate that, while there is variation within and among speakers, characteristics correlated with singleton Georgian ejectives include relative burst amplitude, noise quality following oral release, long, positive voice onset time, and a short period of creaky voice at the onset of a following vowel. Some of these characteristics differ from those of ejective clusters.

  20. Acoustics SIMOPS: managing the unnecessary

    Energy Technology Data Exchange (ETDEWEB)

    Hanton, Samuel John [Nautronix Marine Technology Solutions, Rio de Janeiro, RJ (Brazil)

    2012-07-01

    Time is money, and offshore operations are expensive. The desire therefore, is to increase efficiency through the condensing of schedules. This inevitably leads to SIMOPS of some degree, and this paper discusses SIMOPS along with, more specifically, the challenges they provide to acoustic positioning. (author)

  1. Underwater Acoustic Carbon Nanotube Thermophone

    Science.gov (United States)

    2016-09-23

    the generation of electrical excitation pulsed through an amplifier into an electro-acoustic material (such as a piezoelectric ceramic ...strength. This periodic heating produces temperature waves which propagate into a surrounding medium. The amplitude of the temperature wave ...decreases rapidly as the distance from the conductor increases. Based on the rapid production of these temperature waves ; the net effect is to produce a

  2. Robust acoustic wave manipulation of bubbly liquids

    Energy Technology Data Exchange (ETDEWEB)

    Gumerov, N. A., E-mail: gumerov@umiacs.umd.edu [Institute for Advanced Computer Studies, University of Maryland, College Park, Maryland 20742 (United States); Center for Micro- and Nanoscale Dynamics of Dispersed Systems, Bashkir State University, Ufa 450076 (Russian Federation); Akhatov, I. S. [Center for Design, Manufacturing and Materials, Skolkovo Institute of Science and Technology, Moscow 143026 (Russian Federation); Ohl, C.-D. [Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore); Center for Micro- and Nanoscale Dynamics of Dispersed Systems, Bashkir State University, Ufa 450076 (Russian Federation); Sametov, S. P. [Center for Micro- and Nanoscale Dynamics of Dispersed Systems, Bashkir State University, Ufa 450076 (Russian Federation); Khazimullin, M. V. [Center for Micro- and Nanoscale Dynamics of Dispersed Systems, Bashkir State University, Ufa 450076 (Russian Federation); Institute of Molecule and Crystal Physics, Ufa Research Center of Russian Academy of Sciences, Ufa 450054 (Russian Federation); Gonzalez-Avila, S. R. [Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore)

    2016-03-28

    Experiments with water–air bubbly liquids when exposed to acoustic fields of frequency ∼100 kHz and intensity below the cavitation threshold demonstrate that bubbles ∼30 μm in diameter can be “pushed” away from acoustic sources by acoustic radiation independently from the direction of gravity. This manifests formation and propagation of acoustically induced transparency waves (waves of the bubble volume fraction). In fact, this is a collective effect of bubbles, which can be described by a mathematical model of bubble self-organization in acoustic fields that matches well with our experiments.

  3. 4th Pacific Rim Underwater Acoustics Conference

    CERN Document Server

    Xu, Wen; Cheng, Qianliu; Zhao, Hangfang

    2016-01-01

    These proceedings are a collection of 16 selected scientific papers and reviews by distinguished international experts that were presented at the 4th Pacific Rim Underwater Acoustics Conference (PRUAC), held in Hangzhou, China in October 2013. The topics discussed at the conference include internal wave observation and prediction; environmental uncertainty and coupling to sound propagation; environmental noise and ocean dynamics; dynamic modeling in acoustic fields; acoustic tomography and ocean parameter estimation; time reversal and matched field processing; underwater acoustic localization and communication as well as measurement instrumentations and platforms. These proceedings provide insights into the latest developments in underwater acoustics, promoting the exchange of ideas for the benefit of future research.

  4. Acoustic Replication in Smart Structures Using Active Structural/acoustic Control

    Science.gov (United States)

    Griffin, Steven Fulton

    1995-01-01

    There has been a great deal of research on the use of active vibration control with the goal of changing the vibration characteristics of structures. These vibration characteristics may result in undesirable acoustic fields that radiate from the structure. Traditional active noise control approaches center around canceling the offensive acoustic field using loudspeakers to set up opposing fields. A more recent approach is to use active vibration control techniques to directly modify the vibration characteristics and thus the acoustically radiative properties of the structure. A very effective way of achieving this structural/acoustic control is through the use of smart structures in which sensors and actuators are integrated into the structure itself. The subject of this thesis is to explore the potential for the use of active structural/acoustic control and smart structures in acoustic replication. In acoustic replication, an offensive acoustic response of an acoustically radiative smart structure is modified to match a desired acoustic response using active structural/acoustic control. The desired goal, in this case, is not necessarily suppression but to match the acoustic response of a similar structure that has desired acoustic properties. The model that is developed in detail is an elastic plate with piezoceramic sensors and actuators backed by a rigid, vented cavity. One specific application explored is the acoustic guitar. Detailed information on desired acoustic response of guitars is readily available in the literature, and experimental specimens are relatively easy to obtain. The way such an instrument vibrates in response to excitation of the strings determines the acoustic field that results. The feasibility of changing these vibrational characteristics using active structural/acoustic control is examined in detail including analytical and experimental results. The feasibility of applying acoustic replication to an aircraft cockpit is also examined

  5. Acoustic Microfluidics for Bioanalytical Application

    Science.gov (United States)

    Lopez, Gabriel

    2013-03-01

    This talk will present new methods the use of ultrasonic standing waves in microfluidic systems to manipulate microparticles for the purpose of bioassays and bioseparations. We have recently developed multi-node acoustic focusing flow cells that can position particles into many parallel flow streams and have demonstrated the potential of such flow cells in the development of high throughput, parallel flow cytometers. These experiments show the potential for the creation of high throughput flow cytometers in applications requiring high flow rates and rapid detection of rare cells. This talk will also present the development of elastomeric capture microparticles and their use in acoustophoretic separations. We have developed simple methods to form elastomeric particles that are surface functionalized with biomolecular recognition reagents. These compressible particles exhibit negative acoustic contrast in ultrasound when suspended in aqueous media, blood serum or diluted blood. These particles can be continuously separated from cells by flowing them through a microfluidic device that uses an ultrasonic standing wave to align the blood cells, which exhibit positive acoustic contrast, at a node in the acoustic pressure distribution while aligning the negative acoustic contrast elastomeric particles at the antinodes. Laminar flow of the separated particles to downstream collection ports allows for collection of the separated negative contrast particles and cells. Separated elastomeric particles were analyzed via flow cytometry to demonstrate nanomolar detection for prostate specific antigen in aqueous buffer and picomolar detection for IgG in plasma and diluted blood samples. This approach has potential applications in the development of rapid assays that detect the presence of low concentrations of biomarkers (including biomolecules and cells) in a number of biological sample types. We acknowledge support through the NSF Research Triangle MRSEC.

  6. Shape optimization: Good looks and acoustics too!

    Science.gov (United States)

    D'Antonio, Peter; Cox, Trevor J.; Haas, Steve

    2003-04-01

    One of the challenges in the architectural acoustic design of museums and other public spaces is to develop contemporary scattering surfaces that complement contemporary architecture in the way that statuary, coffered ceilings, columns, and relief ornamentation complemented classic architecture. Often acoustic surfaces satisfy the acoustics, but may or may not satisfy the aesthetics. One approach that has been successful employs a combination of boundary element and multidimensional optimization techniques. The architect supplies the desired shape motif and the acoustician supplies the acoustical performance requirements. The optimization program then provides an Arcousthetic surface, which simultaneously satisfies the architecture, the acoustics, and the aesthetics. The program can be used with diffusive or diffsorptive surfaces. Photos of installations using these acoustic tools and a description of the design of the National Museum of the American Indian will also be presented to illustrate the usefulness of these devices and their impact on architectural acoustics.

  7. Handbook of Signal Processing in Acoustics

    CERN Document Server

    Havelock, David; Vorländer, Michael

    2009-01-01

    The Handbook of Signal Processing in Acoustics presents signal processing as it is practiced in the field of acoustics. The Handbook is organized by areas of acoustics, with recognized leaders coordinating the self-contained chapters of each section. It brings together a wide range of perspectives from over 100 authors to reveal the interdisciplinary nature of signal processing in acoustics. Success in acoustic applications often requires juggling both the acoustic and the signal processing parameters of the problem. This handbook brings the key issues from both into perspective and is complementary to other reference material on the two subjects. It is a unique resource for experts and practitioners alike to find new ideas and techniques within the diversity of signal processing in acoustics.

  8. NMR-Metabolic Methodology in the Study of GM Foods

    Science.gov (United States)

    The 1H NMR methodology used in the study of genetically modified (GM) foodstuff is discussed. The study of transgenic lettuce (Lactuca sativa cv "Luxor") over-expressing the KNAT1 gene from Arabidopsis is presented as a novel study-case. The 1H NMR metabolic profiling was carried out. Twenty-two wat...

  9. nmr spectroscopic study and dft calculations of vibrational analyses ...

    African Journals Online (AJOL)

    Preferred Customer

    ANALYSES, GIAO NMR SHIELDINGS AND 1JCH, 1JCC SPIN-SPIN COUPLING. CONSTANTS ... proton coupled and uncoupled 13C, 15N, DEPT, COSY, HETCOR, INADEQUATE NMR spectra and the magnitude ... methodology an interesting variety of spin-spin coupling constants can be calculated with good accuracy in ...

  10. Facing and Overcoming Sensitivity Challenges in Biomolecular NMR Spectroscopy

    DEFF Research Database (Denmark)

    Ardenkjær-Larsen, Jan Henrik; Boebinger, Gregory S.; Comment, Arnaud

    2015-01-01

    In the Spring of 2013, NMR spectroscopists convened at the Weizmann Institute in Israel to brainstorm on approaches to improve the sensitivity of NMR experiments, particularly when applied in biomolecular settings. This multi‐author interdisciplinary Review presents a state‐of‐the‐art description...

  11. Advanced solid-state NMR spectroscopy of natural organic matter.

    Science.gov (United States)

    Mao, Jingdong; Cao, Xiaoyan; Olk, Dan C; Chu, Wenying; Schmidt-Rohr, Klaus

    2017-05-01

    Solid-state NMR is essential for the characterization of natural organic matter (NOM) and is gaining importance in geosciences and environmental sciences. This review is intended to highlight advanced solid-state NMR techniques, especially a systematic approach to NOM characterization, and their applications to the study of NOM. We discuss some basics of how to acquire high-quality and quantitative solid-state 13 C NMR spectra, and address some common technical mistakes that lead to unreliable spectra of NOM. The identification of specific functional groups in NOM, primarily based on 13 C spectral-editing techniques, is described and the theoretical background of some recently-developed spectral-editing techniques is provided. Applications of solid-state NMR to investigating nitrogen (N) in NOM are described, focusing on limitations of the widely used 15 N CP/MAS experiment and the potential of improved advanced NMR techniques for characterizing N forms in NOM. Then techniques used for identifying proximities, heterogeneities and domains are reviewed, and some examples provided. In addition, NMR techniques for studying segmental dynamics in NOM are reviewed. We also briefly discuss applications of solid-state NMR to NOM from various sources, including soil organic matter, aquatic organic matter, organic matter in atmospheric particulate matter, carbonaceous meteoritic organic matter, and fossil fuels. Finally, examples of NMR-based structural models and an outlook are provided. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Fluid-Rock Characterization and Interactions in NMR Well Logging

    Energy Technology Data Exchange (ETDEWEB)

    George J. Hirasaki; Kishore K. Mohanty

    2005-09-05

    The objective of this report is to characterize the fluid properties and fluid-rock interactions that are needed for formation evaluation by NMR well logging. The advances made in the understanding of NMR fluid properties are summarized in a chapter written for an AAPG book on NMR well logging. This includes live oils, viscous oils, natural gas mixtures, and the relation between relaxation time and diffusivity. Oil based drilling fluids can have an adverse effect on NMR well logging if it alters the wettability of the formation. The effect of various surfactants on wettability and surface relaxivity are evaluated for silica sand. The relation between the relaxation time and diffusivity distinguishes the response of brine, oil, and gas in a NMR well log. A new NMR pulse sequence in the presence of a field gradient and a new inversion technique enables the T{sub 2} and diffusivity distributions to be displayed as a two-dimensional map. The objectives of pore morphology and rock characterization are to identify vug connectivity by using X-ray CT scan, and to improve NMR permeability correlation. Improved estimation of permeability from NMR response is possible by using estimated tortuosity as a parameter to interpolate between two existing permeability models.

  13. Designing of high-resolution photoresists: use of modern NMR ...

    Indian Academy of Sciences (India)

    Applications of improved 1-D/ 2-D NMR spectroscopic techniques have been reviewed for quantitatively estimating the incorporation of different monomers and degree of linearity in resin microstructure. Comparison of the NMR data with those from lithography leads to a distinct correlation between resin microstructure and ...

  14. Probe for high resolution NMR with sample reorientation

    Science.gov (United States)

    Pines, A.; Samoson, A.

    1990-02-06

    An improved NMR probe and method are described which substantially improve the resolution of NMR measurements made on powdered or amorphous or otherwise orientationally disordered samples. The apparatus mechanically varies the orientation of the sample such that the time average of two or more sets of spherical harmonic functions are zero. 8 figs.

  15. Bringing NMR and IR Spectroscopy to High Schools

    Science.gov (United States)

    Bonjour, Jessica L.; Hass, Alisa L.; Pollock, David W.; Huebner, Aaron; Frost, John A.

    2017-01-01

    Development of benchtop, portable Fourier transform nuclear magnetic resonance (NMR) and infrared (IR) spectrometers has opened up opportunities for creating university-high school partnerships that provide high school students with hands-on experience with NMR and IR instruments. With recent changes to the international baccalaureate chemistry…

  16. Quantification of (1)H NMR Spectra from Human Plasma.

    Science.gov (United States)

    de Graaf, Robin A; Prinsen, Hetty; Giannini, Cosimo; Caprio, Sonia; Herzog, Raimund I

    2015-12-01

    Human plasma is a biofluid that is high in information content, making it an excellent candidate for metabolomic studies. (1)H NMR has been a popular technique to detect several dozen metabolites in blood plasma. In order for (1)H NMR to become an automated, high-throughput method, challenges related to (1) the large signal from lipoproteins and (2) spectral overlap between different metabolites have to be addressed. Here diffusion-weighted (1)H NMR is used to separate lipoprotein and metabolite signals based on their large difference in translational diffusion. The metabolite (1)H NMR spectrum is then quantified through spectral fitting utilizing full prior knowledge on the metabolite spectral signatures. Extension of the scan time by 3 minutes or 15% per sample allowed the acquisition of a (1)H NMR spectrum with high diffusion weighting. The metabolite (1)H NMR spectra could reliably be modeled with 28 metabolites. Excellent correlation was found between results obtained with diffusion NMR and ultrafiltration. The combination of minimal sample preparation together with minimal user interaction during processing and quantification provides a metabolomics technique for automated, quantitative (1)H NMR of human plasma.

  17. Rapid prediction of multi-dimensional NMR data sets

    NARCIS (Netherlands)

    Gradmann, S.H.E.; Ader, C.|info:eu-repo/dai/nl/326096639; Heinrich, I.; Nand, D.|info:eu-repo/dai/nl/337731403; Dittmann, M.; Cukkemane, A.A.|info:eu-repo/dai/nl/33285907X; van Dijk, M.|info:eu-repo/dai/nl/325811113; Bonvin, A.M.J.J.|info:eu-repo/dai/nl/113691238; Engelhard, M.; Baldus, M.|info:eu-repo/dai/nl/314410864

    2012-01-01

    We present a computational environment for Fast Analysis of multidimensional NMR DAta Sets (FANDAS) that allows assembling multidimensional data sets from a variety of input parameters and facilitates comparing and modifying such “in silico” data sets during the various stages of the NMR data

  18. $\\beta$-NMR of copper isotopes in ionic liquids

    CERN Multimedia

    We propose to test the feasibility of spin-polarization and $\\beta$-NMR studies on several short-lived copper isotopes, $^{58}$ Cu, $^{74}$Cu and $^{75}$Cu in crystals and liquids. The motivation is given by biological studies of Cu with $\\beta$-NMR in liquid samples, since Cu is present in a large number of enzymes involved in electron transfer and activation of oxygen. The technique is based on spin-polarization via optical pumping in the new VITO beamline. We will use the existing lasers, NMR magnet and NMR chambers and we will prepare a new optical pumping system. The studies will be devoted to tests of achieved $\\beta$-asymmetry in solid hosts, the behaviour of asymmetry when increasing vacuum, and finally NMR scans in ionic liquids. The achieved spin polarization will be also relevant for the plans to measure with high precision the magnetic moments of neutron-rich Cu isotopes.

  19. Acoustic spin pumping in magnetoelectric bulk acoustic wave resonator

    Energy Technology Data Exchange (ETDEWEB)

    Polzikova, N. I., E-mail: polz@cplire.ru; Alekseev, S. G.; Pyataikin, I. I.; Kotelyanskii, I. M.; Luzanov, V. A.; Orlov, A. P. [Kotel’nikov Institute of Radio Engineering and Electronics of Russian Academy of Sciences, Mokhovaya 11, building 7, Moscow, 125009 (Russian Federation)

    2016-05-15

    We present the generation and detection of spin currents by using magnetoelastic resonance excitation in a magnetoelectric composite high overtone bulk acoustic wave (BAW) resonator (HBAR) formed by a Al-ZnO-Al-GGG-YIG-Pt structure. Transversal BAW drives magnetization oscillations in YIG film at a given resonant magnetic field, and the resonant magneto-elastic coupling establishes the spin-current generation at the Pt/YIG interface. Due to the inverse spin Hall effect (ISHE) this BAW-driven spin current is converted to a dc voltage in the Pt layer. The dependence of the measured voltage both on magnetic field and frequency has a resonant character. The voltage is determined by the acoustic power in HBAR and changes its sign upon magnetic field reversal. We compare the experimentally observed amplitudes of the ISHE electrical field achieved by our method and other approaches to spin current generation that use surface acoustic waves and microwave resonators for ferromagnetic resonance excitation, with the theoretically expected values.

  20. Active elimination of radio frequency interference for improved signal-to-noise ratio for in-situ NMR experiments in strong magnetic field gradients.

    Science.gov (United States)

    Ibrahim, M; Pardi, C I; Brown, T W C; McDonald, P J

    2018-02-01

    Improvement in the signal-to-noise ratio of Nuclear Magnetic Resonance (NMR) systems may be achieved either by increasing the signal amplitude or by decreasing the noise. The noise has multiple origins - not all of which are strictly "noise": incoherent thermal noise originating in the probe and pre-amplifiers, probe ring down or acoustic noise and coherent externally broadcast radio frequency transmissions. The last cannot always be shielded in open access experiments. In this paper, we show that pulsed, low radio-frequency data communications are a significant source of broadcast interference. We explore two signal processing methods of de-noising short T 2 ∗ NMR experiments corrupted by these communications: Linear Predictive Coding (LPC) and the Discrete Wavelet Transform (DWT). Results are shown for numerical simulations and experiments conducted under controlled conditions with pseudo radio frequency interference. We show that both the LPC and DWT methods have merit. Copyright © 2018 Elsevier Inc. All rights reserved.

  1. Orientational Glasses: NMR and Electric Susceptibility Studies

    Directory of Open Access Journals (Sweden)

    Neil Sullivan

    2017-11-01

    Full Text Available We review the results of a wide range of nuclear magnetic resonance (NMRmeasurements of the local order parameters and the molecular dynamics of solid ortho-para hydrogen mixtures and solid nitrogen-argon mixtures that form novel molecular orientational glass states at low temperatures. From the NMR measurements, the distribution of the order parameters can be deduced and, in terms of simple models, used to analyze the thermodynamic measurements of the heat capacities of these systems. In addition, studies of the dielectric susceptibilities of the nitrogen-argon mixtures are reviewed in terms of replica symmetry breaking analogous to that observed for spin glass states. It is shown that this wide set of experimental results is consistent with orientation or quadrupolar glass ordering of the orientational degrees of freedom.

  2. NMR studies of polysaccharides from brown seaweeds

    Energy Technology Data Exchange (ETDEWEB)

    Noseda, M.D.; Tisher, C.A.; Gorin, P.A.J.; Duarte, M.E.R. [Parana Univ., Curitiba, PR (Brazil). Dept. de Bioquimica; Cerezo, A.S. [Buenos Aires Univ. Nacional (Argentina). Dept. de Quimica Organica

    1997-12-31

    Alginic acid is the major intercellular polysaccharide serving as matrix in the brown algae and is comprised of an unbranched chain of (1->4)-linked {beta}-D-mannuronic acid (M) and {alpha}-L-guluronic acid (G), arranged in a blockwise fashion. The composition of the monomer residues and the block structure varies depending on the source of the polymer. The selective binding of cations to alginate accounts for its ability to form gels, which is dependent on the number and lenght of the G-blocks. They are widely used industrially for their ability to retain water, and for their gelling, viscosifying and stabilizing properties (Smidsrod and draget, 1996). In this study, alginate composition and block structure in Sargassum stenophyllum has been determined by chemical methods and NMR spectroscopic analysis. (author) 4 refs., 3 figs.

  3. Two-Dimensional NMR Lineshape Analysis

    Science.gov (United States)

    Waudby, Christopher A.; Ramos, Andres; Cabrita, Lisa D.; Christodoulou, John

    2016-04-01

    NMR titration experiments are a rich source of structural, mechanistic, thermodynamic and kinetic information on biomolecular interactions, which can be extracted through the quantitative analysis of resonance lineshapes. However, applications of such analyses are frequently limited by peak overlap inherent to complex biomolecular systems. Moreover, systematic errors may arise due to the analysis of two-dimensional data using theoretical frameworks developed for one-dimensional experiments. Here we introduce a more accurate and convenient method for the analysis of such data, based on the direct quantum mechanical simulation and fitting of entire two-dimensional experiments, which we implement in a new software tool, TITAN (TITration ANalysis). We expect the approach, which we demonstrate for a variety of protein-protein and protein-ligand interactions, to be particularly useful in providing information on multi-step or multi-component interactions.

  4. Long Lived NMR Signal in Bone

    CERN Document Server

    Zhang, Boyang; Khitrin, Anatoly; Jerschow, Alexej

    2012-01-01

    Solids and rigid tissues such as bone, ligaments, and tendons, typically appear dark in magnetic resonance imaging (MRI), which is due to the extremely short-lived proton nuclear magnetic resonance (NMR) signals. This short lifetime is due to strong dipolar interactions between immobilized proton spins, which render it challenging to detect these signals with sufficient resolution and sensitivity. Here we show the possibility of exciting long-lived signals in cortical bone tissue with a signature consistent with that of bound water signals. Contrary to long-standing belief, it is further shown that dipolar coupling networks are an integral requirement for the excitation of these long-lived signals. The use of these signals could enhance the ability to visualize rigid tissues and solid samples with high sensitivity, resolution, and specificity via MRI.

  5. NMR Metabolomics Analysis of Parkinson's Disease

    Science.gov (United States)

    Lei, Shulei; Powers, Robert

    2015-01-01

    Parkinson's disease (PD) is a neurodegenerative disease, which is characterized by progressive death of dopaminergic neurons in the substantia nigra pars compacta. Although mitochondrial dysfunction and oxidative stress are linked to PD pathogenesis, its etiology and pathology remain to be elucidated. Metabolomics investigates metabolite changes in biofluids, cell lysates, tissues and tumors in order to correlate these metabolomic changes to a disease state. Thus, the application of metabolomics to investigate PD provides a systematic approach to understand the pathology of PD, to identify disease biomarkers, and to complement genomics, transcriptomics and proteomics studies. This review will examine current research into PD mechanisms with a focus on mitochondrial dysfunction and oxidative stress. Neurotoxin-based PD animal models and the rationale for metabolomics studies in PD will also be discussed. The review will also explore the potential of NMR metabolomics to address important issues related to PD treatment and diagnosis. PMID:26078917

  6. NMR structures reveal how oxidation inactivates thrombomodulin.

    Science.gov (United States)

    Wood, Matthew J; Becvar, L Amaya; Prieto, Judith Helena; Melacini, Giuseppe; Komives, Elizabeth A

    2003-10-21

    Oxidation of Met 388, one of the three linker residues connecting the fourth and fifth EGF-like domains of thrombomodulin (TM), is deleterious for TM activity. An NMR structure of the smallest active fragment of TM (TMEGF45) and a crystal structure of a larger fragment (TMEGF456) bound to thrombin both show that Met 388 is packed into the fifth domain. Using multidimensional NMR, we have solved the structure of TMEGF45 in which Met 388 is oxidized (TMEGF45ox) and the structure of TMEGF45 in which Met 388 is mutated to Leu (TMEGF45ML). Comparison of the structures shows that the fifth domain has a somewhat different structure depending on the residue at position 388, and several of the thrombin-binding residues are packed into the fifth domain in the oxidized protein while they are exposed and free to interact with thrombin in the native structure and the Met-Leu mutant. This observation is consistent with kinetic measurements showing that the K(m) for TMEGF45ox binding to thrombin is 3.3-fold higher than for the native protein. Most importantly, the connection between the two domains, as indicated by interdomain NOEs, appears to be essential for activity. In the TMEGF45ox structure which has a reduced k(cat) for protein C activation by the thrombin-TMEGF45ox complex, interaction between the two domains is lost. Conversely, a tighter connection is observed between the two domains in TMEGF45ML, which has a higher k(cat) for protein C activation by the thrombin-TMEGF45ML complex.

  7. Hidden acoustic information revealed by intentional nonlinearity

    Science.gov (United States)

    Dowling, David R.

    2017-11-01

    Acoustic waves are omnipresent in modern life and are well described by the linearized equations of fluid dynamics. Once generated, acoustic waves carry and collect information about their source and the environment through which they propagate, respectively, and this information may be retrieved by analyzing recordings of these waves. Because of this, acoustics is the primary means for observation, surveillance, reconnaissance, and remote sensing in otherwise opaque environments, such as the Earth's oceans and crust, and the interior of the human body. For such information-retrieval tasks, acoustic fields are nearly always interrogated within their recorded frequency range or bandwidth. However, this frequency-range restriction is not general; acoustic fields may also carry (hidden) information at frequencies outside their bandwidth. Although such a claim may seem counter intuitive, hidden acoustic-field information can be revealed by re-introducing a marquee trait of fluid dynamics: nonlinearity. In particular, an intentional quadratic nonlinearity - a form of intra-signal heterodyning - can be used to obtain acoustic field information at frequencies outside a recorded acoustic field's bandwidth. This quadratic nonlinearity enables a variety of acoustic remote sensing applications that were long thought to be impossible. In particular, it allows the detrimental effects of sparse recordings and random scattering to be suppressed when the original acoustic field has sufficient bandwidth. In this presentation, the topic is developed heuristically, with a just brief exposition of the relevant mathematics. Hidden acoustic field information is then revealed from simulated and measured acoustic fields in simple and complicated acoustic environments involving frequencies from a few Hertz to more than 100 kHz, and propagation distances from tens of centimeters to hundreds of kilometers. Sponsored by ONR, NAVSEA, and NSF.

  8. ImatraNMR: Novel software for batch integration and analysis of quantitative NMR spectra

    Science.gov (United States)

    Mäkelä, A. V.; Heikkilä, O.; Kilpeläinen, I.; Heikkinen, S.

    2011-08-01

    Quantitative NMR spectroscopy is a useful and important tool for analysis of various mixtures. Recently, in addition of traditional quantitative 1D 1H and 13C NMR methods, a variety of pulse sequences aimed for quantitative or semiquantitative analysis have been developed. To obtain actual usable results from quantitative spectra, they must be processed and analyzed with suitable software. Currently, there are many processing packages available from spectrometer manufacturers and third party developers, and most of them are capable of analyzing and integration of quantitative spectra. However, they are mainly aimed for processing single or few spectra, and are slow and difficult to use when large numbers of spectra and signals are being analyzed, even when using pre-saved integration areas or custom scripting features. In this article, we present a novel software, ImatraNMR, designed for batch analysis of quantitative spectra. In addition to capability of analyzing large number of spectra, it provides results in text and CSV formats, allowing further data-analysis using spreadsheet programs or general analysis programs, such as Matlab. The software is written with Java, and thus it should run in any platform capable of providing Java Runtime Environment version 1.6 or newer, however, currently it has only been tested with Windows and Linux (Ubuntu 10.04). The software is free for non-commercial use, and is provided with source code upon request.

  9. Acoustic metamaterial design and applications

    Science.gov (United States)

    Zhang, Shu

    The explosion of interest in metamaterials is due to the dramatically increased manipulation ability over light as well as sound waves. This material research was stimulated by the opportunity to develop an artificial media with negative refractive index and the application in superlens which allows super-resolution imaging. High-resolution acoustic imaging techniques are the essential tools for nondestructive testing and medical screening. However, the spatial resolution of the conventional acoustic imaging methods is restricted by the incident wavelength of ultrasound. This is due to the quickly fading evanescent fields which carry the subwavelength features of objects. By focusing the propagating wave and recovering the evanescent field, a flat lens with negative-index can potentially overcome the diffraction limit. We present the first experimental demonstration of focusing ultrasound waves through a flat acoustic metamaterial lens composed of a planar network of subwavelength Helmholtz resonators. We observed a tight focus of half-wavelength in width at 60.5 KHz by imaging a point source. This result is in excellent agreement with the numerical simulation by transmission line model in which we derived the effective mass density and compressibility. This metamaterial lens also displays variable focal length at different frequencies. Our experiment shows the promise of designing compact and light-weight ultrasound imaging elements. Moreover, the concept of metamaterial extends far beyond negative refraction, rather giving enormous choice of material parameters for different applications. One of the most interesting examples these years is the invisible cloak. Such a device is proposed to render the hidden object undetectable under the flow of light or sound, by guiding and controlling the wave path through an engineered space surrounding the object. However, the cloak designed by transformation optics usually calls for a highly anisotropic metamaterial, which

  10. Acoustic reflex and general anaesthesia.

    Science.gov (United States)

    Farkas, Z

    1983-01-01

    Infant and small children are not always able to cooperate in impedance measurements. For this reason it was decided, -in special cases, -to perform acoustic reflex examination under general anaesthesia. The first report on stapedius reflex and general anaesthesia was published by Mink et al. in 1981. Under the effect of Tiobutabarbital, Propanidid and Diazepam there is no reflex response. Acoustic reflex can be elicited with Ketamin-hydrochlorid and Alphaxalone-alphadolone acetate narcosis. The reflex threshold remains unchanged and the amplitude of muscle contraction is somewhat increased. The method was used: 1. to assess the type and degree of hearing loss in children with cleft palate and/or lip prior to surgery. 2. to exclude neuromuscular disorders with indication of pharyngoplasties. 3. to quantify hearing level in children--mostly multiply handicapped--with retarded speech development. The results of Behavioral Observation and Impedance Audiometry are discussed and evaluated.

  11. [Acoustic information in snoring noises].

    Science.gov (United States)

    Janott, C; Schuller, B; Heiser, C

    2017-02-01

    More than one third of all people snore regularly. Snoring is a common accompaniment of obstructive sleep apnea (OSA) and is often disruptive for the bed partner. This work gives an overview of the history of and state of research on acoustic analysis of snoring for classification of OSA severity, detection of obstructive events, measurement of annoyance, and identification of the sound excitation location. Based on these objectives, searches were conducted in the literature databases PubMed and IEEE Xplore. Publications dealing with the respective objectives according to title and abstract were selected from the search results. A total of 48 publications concerning the above objectives were considered. The limiting factor of many studies is the small number of subjects upon which the analyses are based. Recent research findings show promising results, such that acoustic analysis may find a place in the framework of sleep diagnostics, thus supplementing the recognized standard methods.

  12. Acoustic biotelemetry from Slocum Gliders

    Science.gov (United States)

    Oliver, M. J.; Haulsee, D.; Breece, M.; Kohut, J. T.; Fox, D. A.; Wetherbee, B.; Cimino, M. A.

    2016-02-01

    The integration of biotelemetry and Slocum electric gliders presents new opportunities and challenges for interpreting the relationship between acoustically telemetered animals and the environment. Slocum gliders are able to stay in the field for extended periods (> 90 days) while collecting high-resolution data that can be used to reconstruct subsurface habitats. Here we present several case studies that compare integrated and externally mounted acoustic receiver technologies aboard Slocum gliders, compare detection efficiency between coastal arrays and Slocum gliders, investigate signal detectability in coastal habitats, and identify habitat associations of migrating species. Our studies leverage several ongoing tagging efforts, and would not be possible without a highly collaborative biotelemetry community. Slocum gliders are a robust technology that augments existing biotelemetry arrays and enable dynamic sampling of environments that extend beyond the feasibility of stationary arrays. The platforms are ideal for integrating biotelemetry into ocean observing and can provide ecologically relevant habitat associations that assist in the management of telemetered species.

  13. Cooperative OFDM underwater acoustic communications

    CERN Document Server

    Cheng, Xilin; Cheng, Xiang

    2016-01-01

    Following underwater acoustic channel modeling, this book investigates the relationship between coherence time and transmission distances. It considers the power allocation issues of two typical transmission scenarios, namely short-range transmission and medium-long range transmission. For the former scenario, an adaptive system is developed based on instantaneous channel state information. The primary focus is on cooperative dual-hop orthogonal frequency division multiplexing (OFDM). This book includes the decomposed fountain codes designed to enable reliable communications with higher energy efficiency. It covers the Doppler Effect, which improves packet transmission reliability for effective low-complexity mirror-mapping-based intercarrier interference cancellation schemes capable of suppressing the intercarrier interference power level. Designed for professionals and researchers in the field of underwater acoustic communications, this book is also suitable for advanced-level students in electrical enginee...

  14. Oscillating nonlinear acoustic shock waves

    DEFF Research Database (Denmark)

    Gaididei, Yuri; Rasmussen, Anders Rønne; Christiansen, Peter Leth

    2016-01-01

    We investigate oscillating shock waves in a tube using a higher order weakly nonlinear acoustic model. The model includes thermoviscous effects and is non isentropic. The oscillating shock waves are generated at one end of the tube by a sinusoidal driver. Numerical simulations show...... that at resonance a stationary state arise consisting of multiple oscillating shock waves. Off resonance driving leads to a nearly linear oscillating ground state but superimposed by bursts of a fast oscillating shock wave. Based on a travelling wave ansatz for the fluid velocity potential with an added 2'nd order...... polynomial in the space and time variables, we find analytical approximations to the observed single shock waves in an infinitely long tube. Using perturbation theory for the driven acoustic system approximative analytical solutions for the off resonant case are determined....

  15. Piezoelectric fibers for conformal acoustics.

    Science.gov (United States)

    Chocat, Noémie; Lestoquoy, Guillaume; Wang, Zheng; Rodgers, Daniel M; Joannopoulos, John D; Fink, Yoel

    2012-10-09

    Ultrasound transducers have many important applications in medical, industrial, and environmental settings. Large-active-area piezoelectric fibers are presented here, which can be woven into extended and flexible ultrasound transducing fabrics. This work opens significant opportunities for large-area, flexible and adjustable acoustic emission and sensing for a variety of emerging applications. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Isogeometric analysis of acoustic scattering

    OpenAIRE

    Venås, Jon Vegard

    2015-01-01

    Acoustic scattering has been thoroughly analyzed with the use of finite element analysis (FEA). The problem at hand is a coupled fluid-structure interaction problem on an unbounded domain, where an object of elastic material is surrounded by fluid. Using physical assumptions, the fluid is described by the wave equation which is transformed to the Helmholtz equation. That is, the frequency domain is considered instead of the time domain. In particular one is interested in the scattered pressur...

  17. Acoustic tomography. Laboratory technique Implementation.

    Science.gov (United States)

    Galvis, Jorge; Carvajal, Jenny

    2010-05-01

    From geomechanical tests carried out on rocks it is possible to determine its physico-mechanical properties, which relate the strain and applied stress; even so, conventional tests do not allow to identify how stress is distributed and how it has affected porous media. Today, techniques like acoustic tomography widely used in medicine, geophysics and others sciences, generates images by sections of the interior of a body. Acoustic tomography allows inferring the stress state within porous media; since wave velocities are closely related to media density, if a stress is applied to a rock, it will generate grains compaction and this will be showed by an increase of wave velocity. Implementation was conducted on rock plugs under diverse stress fields, simultaneously recording P-wave velocities (Compressional) on perpendicular planes to sample vertical axis. Transmission and reception of acoustic waves through porous media were done by piezoelectric crystals (PZT) used as sensors. A transmitting crystal excited by a voltage pulse causes a mechanical vibration, which travels across media; this is known as inverse piezoelectric effect. This vibration is recorded by a receiving crystal in which the direct piezoelectric effect appears; which dictates that if a piezoelectric is disturbed mechanically, an electrical signal between its terminals will appear. This electrical signal is used to obtain the wave velocity. Nevertheless, acoustic tomography corresponds to one of those called inverse Problems that arise when from observed data the model parameters must be obtained; in this way, tomography involves iterative reconstruction techniques (ART or SIRT) which are projections of observed data and its later inversion. Obtained results are cross-sectional images of velocity within the rock. In these images it is possible to identify where stress has a greater concentration observing the color map generated; thus, a greater velocity density area corresponding to a greater

  18. Acoustic Properties of Absorbent Asphalts

    Science.gov (United States)

    Trematerra, Amelia; Lombardi, Ilaria

    2017-08-01

    Road traffic is one of the greater cause of noise pollution in urban centers; a prolonged exposure to this source of noise disturbs populations subjected to it. In this paper is reported a study on the absorbent coefficients of asphalt. The acoustic measurements are carried out with a impedance tube (tube of Kundt). The sample are measured in three conditions: with dry material (traditional), “wet” asphalt and “dirty” asphalt.

  19. Acoustic telemetry and fisheries management

    Science.gov (United States)

    Crossin, Glenn T.; Heupel, Michelle R.; Holbrook, Christopher; Hussey, Nigel E.; Lowerre-Barbieri, Susan K; Nguyen, Vivian M.; Raby, Graham D.; Cooke, Steven J.

    2017-01-01

    This paper reviews the use of acoustic telemetry as a tool for addressing issues in fisheries management, and serves as the lead to the special Feature Issue of Ecological Applications titled “Acoustic Telemetry and Fisheries Management”. Specifically, we provide an overview of the ways in which acoustic telemetry can be used to inform issues central to the ecology, conservation, and management of exploited and/or imperiled fish species. Despite great strides in this area in recent years, there are comparatively few examples where data have been applied directly to influence fisheries management and policy. We review the literature on this issue, identify the strengths and weaknesses of work done to date, and highlight knowledge gaps and difficulties in applying empirical fish telemetry studies to fisheries policy and practice. We then highlight the key areas of management and policy addressed, as well as the challenges that needed to be overcome to do this. We conclude with a set of recommendations about how researchers can, in consultation with stock assessment scientists and managers, formulate testable scientific questions to address and design future studies to generate data that can be used in a meaningful way by fisheries management and conservation practitioners. We also urge the involvement of relevant stakeholders (managers, fishers, conservation societies, etc.) early on in the process (i.e. in the co-creation of research projects), so that all priority questions and issues can be addressed effectively.

  20. Generation and control of acoustic cavitation structure.

    Science.gov (United States)

    Bai, Lixin; Xu, Weilin; Deng, Jingjun; Li, Chao; Xu, Delong; Gao, Yandong

    2014-09-01

    The generation and control of acoustic cavitation structure are a prerequisite for application of cavitation in the field of ultrasonic sonochemistry and ultrasonic cleaning. The generation and control of several typical acoustic cavitation structures (conical bubble structure, smoker, acoustic Lichtenberg figure, tailing bubble structure, jet-induced bubble structures) in a 20-50 kHz ultrasonic field are investigated. Cavitation bubbles tend to move along the direction of pressure drop in the region in front of radiating surface, which are the premise and the foundation of some strong acoustic cavitation structure formation. The nuclei source of above-mentioned acoustic cavitation structures is analyzed. The relationship and mutual transformation of these acoustic cavitation structures are discussed. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Acoustic levitation of a large solid sphere

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Marco A. B., E-mail: marcobrizzotti@gmail.com [Institute of Physics, University of São Paulo, São Paulo 05508-090 (Brazil); Bernassau, Anne L. [School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom); Adamowski, Julio C. [Department of Mechatronics and Mechanical Systems Engineering, Escola Politécnica, University of São Paulo, São Paulo 05508-030 (Brazil)

    2016-07-25

    We demonstrate that acoustic levitation can levitate spherical objects much larger than the acoustic wavelength in air. The acoustic levitation of an expanded polystyrene sphere of 50 mm in diameter, corresponding to 3.6 times the wavelength, is achieved by using three 25 kHz ultrasonic transducers arranged in a tripod fashion. In this configuration, a standing wave is created between the transducers and the sphere. The axial acoustic radiation force generated by each transducer on the sphere was modeled numerically as a function of the distance between the sphere and the transducer. The theoretical acoustic radiation force was verified experimentally in a setup consisting of an electronic scale and an ultrasonic transducer mounted on a motorized linear stage. The comparison between the numerical and experimental acoustic radiation forces presents a good agreement.

  2. Acoustic communication in plant-animal interactions.

    Science.gov (United States)

    Schöner, Michael G; Simon, Ralph; Schöner, Caroline R

    2016-08-01

    Acoustic communication is widespread and well-studied in animals but has been neglected in other organisms such as plants. However, there is growing evidence for acoustic communication in plant-animal interactions. While knowledge about active acoustic signalling in plants (i.e. active sound production) is still in its infancy, research on passive acoustic signalling (i.e. reflection of animal sounds) revealed that bat-dependent plants have adapted to the bats' echolocation systems by providing acoustic reflectors to attract their animal partners. Understanding the proximate mechanisms and ultimate causes of acoustic communication will shed light on an underestimated dimension of information transfer between plants and animals. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. NMR data visualization, processing, and analysis on mobile devices.

    Science.gov (United States)

    Cobas, Carlos; Iglesias, Isaac; Seoane, Felipe

    2015-08-01

    Touch-screen computers are emerging as a popular platform for many applications, including those in chemistry and analytical sciences. In this work, we present our implementation of a new NMR 'app' designed for hand-held and portable touch-controlled devices, such as smartphones and tablets. It features a flexible architecture formed by a powerful NMR processing and analysis kernel and an intuitive user interface that makes full use of the smart devices haptic capabilities. Routine 1D and 2D NMR spectra acquired in most NMR instruments can be processed in a fully unattended way. More advanced experiments such as non-uniform sampled NMR spectra are also supported through a very efficient parallelized Modified Iterative Soft Thresholding algorithm. Specific technical development features as well as the overall feasibility of using NMR software apps will also be discussed. All aspects considered the functionalities of the app allowing it to work as a stand-alone tool or as a 'companion' to more advanced desktop applications such as Mnova NMR. Copyright © 2015 John Wiley & Sons, Ltd.

  4. Determination of surface relaxivity from NMR diffusion measurements.

    Science.gov (United States)

    Slijkerman, W F; Hofman, J P

    1998-01-01

    Nuclear magnetic resonance (NMR) T2-decay measurements are usually interpreted in terms of pore-size distributions. The T2 relaxation time of a water-wet pore is proportional to the size of the pore via surface relaxivity. Quantitative knowledge of the surface relaxivity is important when T2 spectra are to be used for further use such as NMR derived capillary curves. In this study, we demonstrate that surface relaxivity can be directly determined from NMR measurements. Diffusion of hydrogen spins is restricted by the pore size and this effect is independent of surface relaxivity. Hence, surface relaxivity can be determined by combining restricted diffusion and T2-relaxation. The latter two effects are measured simultaneously in a NMR T2 decay measurement performed in a static magnetic field gradient. This method generalises existing ones for uniform pore systems to full pore-size distributions of realistic rocks. We have performed laboratory NMR diffusion measurements on a number of sandstone core plugs. The surface relaxivities found from these data are compared to those obtained from other methods. This method of measuring surface relaxivity can in principle be applied to NMR data obtained in boreholes which leads to a new application of NMR logging in the characterisation of oil and gas reservoirs.

  5. Can NMR solve some significant challenges in metabolomics?

    Science.gov (United States)

    Nagana Gowda, G. A.; Raftery, Daniel

    2015-11-01

    The field of metabolomics continues to witness rapid growth driven by fundamental studies, methods development, and applications in a number of disciplines that include biomedical science, plant and nutrition sciences, drug development, energy and environmental sciences, toxicology, etc. NMR spectroscopy is one of the two most widely used analytical platforms in the metabolomics field, along with mass spectrometry (MS). NMR's excellent reproducibility and quantitative accuracy, its ability to identify structures of unknown metabolites, its capacity to generate metabolite profiles using intact bio-specimens with no need for separation, and its capabilities for tracing metabolic pathways using isotope labeled substrates offer unique strengths for metabolomics applications. However, NMR's limited sensitivity and resolution continue to pose a major challenge and have restricted both the number and the quantitative accuracy of metabolites analyzed by NMR. Further, the analysis of highly complex biological samples has increased the demand for new methods with improved detection, better unknown identification, and more accurate quantitation of larger numbers of metabolites. Recent efforts have contributed significant improvements in these areas, and have thereby enhanced the pool of routinely quantifiable metabolites. Additionally, efforts focused on combining NMR and MS promise opportunities to exploit the combined strength of the two analytical platforms for direct comparison of the metabolite data, unknown identification and reliable biomarker discovery that continue to challenge the metabolomics field. This article presents our perspectives on the emerging trends in NMR-based metabolomics and NMR's continuing role in the field with an emphasis on recent and ongoing research from our laboratory.

  6. Deep-Water Ambient Noise Profiling; Marine Sediment Acoustics; and Doppler Geo-Acoustic Spectroscopy

    Science.gov (United States)

    2013-09-30

    Acoustics; and Doppler Geo-Acoustic Spectroscopy Michael J. Buckingham Marine Physical Laboratory, Scripps Institution of Oceanography University...second-order spatial statistics of the noise. 2) Marine sediment acoustics Develop a unified, physics -based model of sound wave and shear wave...T. K. Berger and M. J. Buckingham, “Sensitivity of an underwater acoustic array to ultra-high energy neutrinos,” Astroparticle Phys., 697, 1-14

  7. Acoustic communication in insect disease vectors

    OpenAIRE

    Felipe de Mello Vigoder; Michael Gordon Ritchie; Gabriella Gibson; Alexandre Afranio Peixoto

    2013-01-01

    Acoustic signalling has been extensively studied in insect species, which has led to a better understanding of sexual communication, sexual selection and modes of speciation. The significance of acoustic signals for a blood-sucking insect was first reported in the XIX century by Christopher Johnston, studying the hearing organs of mosquitoes, but has received relatively little attention in other disease vectors until recently. Acoustic signals are often associated with mating behaviour and se...

  8. Canada Basin Acoustic Propagation Experiment (CANAPE)

    Science.gov (United States)

    2015-09-30

    fundamental limits to the use of acoustic methods and signal processing imposed by ice and ocean processes in the new Arctic. The hope is that these...1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Canada Basin Acoustic Propagation Experiment (CANAPE...ocean structure. Changes in sea ice and the water column affect both acoustic propagation and ambient noise. This implies that what was learned

  9. Experimental Acoustic Evaluation of an Auditorium

    Directory of Open Access Journals (Sweden)

    Marina Dana Ţopa

    2012-01-01

    Full Text Available The paper presents a case history: the acoustical analysis of a rectangular auditorium. The following acoustical parameters were evaluated: early decay time, reverberation time, clarity, definition, and center time. The excitation signal was linear sweep sine and additional analysis was carried out: peak-to-noise ratio, reverberation time for empty and occupied room, standard deviation of acoustical parameters, diffusion, and just noticeable differences analysis. Conclusions about room’s destination and modeling were drawn in the end.

  10. Acoustics of a Mixed Porosity Felt Airfoil

    Science.gov (United States)

    2016-06-06

    NUWC-NPT Technical Report 12,212 6 June 2016 Acoustics of a Mixed Porosity Felt Airfoil Aren M. Hellum Undersea Warfare Weapons...Research project “ Acoustics and Performance of Lifting Surfaces with Mixed Porosity.” The technical reviewer for this report was Dr. Jesse Belden...MM-YYYY) 06-06-2016 2. REPORT TYPE Technical Report 3. DATES COVERED (From – To) 4. TITLE AND SUBTITLE Acoustics of a Mixed Porosity

  11. Anisotropic and Negative Acoustic Index Metamaterials

    OpenAIRE

    Fok, Lee Ren

    2010-01-01

    Microstructured materials are used in material science and engineering to attain desired material properties. Acoustic metamaterials are a rapidly growing area in this field of engineered materials that use deep subwavelength microstructures to attain exotic acoustic properties unavailable in nature. These properties, such as negative acoustic index, allow unprecedented capabilities such as sub-diffraction limit resolution, which have the potential to greatly improve existing technologies l...

  12. Active elastic metamaterials with applications in acoustics

    OpenAIRE

    Pope, Simon; Laalej, Hatim; Daley, Steve

    2012-01-01

    International audience; Elastic metamaterials provide a new approach to solving existing problems in acoustics. They have also been associated with novel concepts such as acoustic invisibility and subwavelength imaging. To be applied to many of the proposed applications a metamaterial would need to have the desired mass density and elastic moduli over a wide frequency band. To minimise scatter in acoustics applications the impedance of solid elastic metamaterials also need to be matched to th...

  13. Acoustic resonance for nonmetallic mine detection

    Energy Technology Data Exchange (ETDEWEB)

    Kercel, S.W.

    1998-04-01

    The feasibility of acoustic resonance for detection of plastic mines was investigated by researchers at the Oak Ridge National Laboratory`s Instrumentation and Controls Division under an internally funded program. The data reported in this paper suggest that acoustic resonance is not a practical method for mine detection. Representative small plastic anti-personnel mines were tested, and were found to not exhibit detectable acoustic resonances. Also, non-metal objects known to have strong acoustic resonances were tested with a variety of excitation techniques, and no practical non-contact method of exciting a consistently detectable resonance in a buried object was discovered. Some of the experimental data developed in this work may be useful to other researchers seeking a method to detect buried plastic mines. A number of excitation methods and their pitfalls are discussed. Excitation methods that were investigated include swept acoustic, chopped acoustic, wavelet acoustic, and mechanical shaking. Under very contrived conditions, a weak response that could be attributed to acoustic resonance was observed, but it does not appear to be practical as a mine detection feature. Transfer properties of soil were investigated. Impulse responses of several representative plastic mines were investigated. Acoustic leakage coupling, and its implications as a disruptive mechanism were investigated.

  14. Acoustic rehabilitation of a music classroom

    Directory of Open Access Journals (Sweden)

    Paloma Pérez Castillo

    2013-05-01

    Full Text Available Generallly, music in classrooms lacks apropiate acoustic characteristics. With the help of an análisis of perceptive variables and plysical parameters, those acoustic values which guarantee the acoustic confort have been able identify. These values taken like a criteria to the acoustic restoration of a music classroom sutied before, the reached improvement results satisfactory. With all ol them it pretends to contribute to a better effectiveness of the oral and musical communication for a good development of the music didactics.

  15. Acoustic concentration of particles in fluid flow

    Science.gov (United States)

    Ward, Michael D.; Kaduchak, Gregory

    2010-11-23

    An apparatus for acoustic concentration of particles in a fluid flow includes a substantially acoustically transparent membrane and a vibration generator that define a fluid flow path therebetween. The fluid flow path is in fluid communication with a fluid source and a fluid outlet and the vibration generator is disposed adjacent the fluid flow path and is capable of producing an acoustic field in the fluid flow path. The acoustic field produces at least one pressure minima in the fluid flow path at a predetermined location within the fluid flow path and forces predetermined particles in the fluid flow path to the at least one pressure minima.

  16. A short history of bad acoustics.

    Science.gov (United States)

    Wright, M C M

    2006-10-01

    Every branch of science attracts its share of cranks and pseudoscientists, and acoustics has been no exception. A brief survey of those who touched on acoustics is given with quotations from the more interesting or egregious examples. A contrast is drawn between the nineteenth century contrarian's quarrel with particular theories and the modern new age wholesale rejection of theory. This world-view is traced back to the later scientific writings of Goethe. Examples of pseudoscience applied to biomedical acoustics, architectural acoustics, and audio reproduction are given.

  17. Acoustic concentration of particles in fluid flow

    Energy Technology Data Exchange (ETDEWEB)

    Ward, Michael W.; Kaduchak, Gregory

    2017-08-15

    Disclosed herein is a acoustic concentration of particles in a fluid flow that includes a substantially acoustically transparent membrane and a vibration generator that define a fluid flow path therebetween. The fluid flow path is in fluid communication with a fluid source and a fluid outlet and the vibration generator is disposed adjacent the fluid flow path and is capable of producing an acoustic field in the fluid flow path. The acoustic field produces at least one pressure minima in the fluid flow path at a predetermined location within the fluid flow path and forces predetermined particles in the fluid flow path to the at least one pressure minima.

  18. Acoustic Based Tactical Control of Underwater Vehicles

    National Research Council Canada - National Science Library

    Marr, William

    2003-01-01

    Advances in command and control of Autonomous Underwater Vehicles (AUVs) using acoustic communications are crucial to future Fleet objectives, particularly in Very Shallow Water Mine Countermeasures (VSW MCM...

  19. Electromagnetically generated acoustic determination of delamination

    Science.gov (United States)

    Imaino, W.

    1991-04-01

    Previous work has demonstrated a technique for acoustically detecting localized delamination of metallized patterns on insulating substrates [W. Imaino, L. Crawforth, A. C. Munce, and A. Julaiana, in Proceedings of the IEEE Ultrasonics Symposium, edited by B. R. McAvoy (IEEE, New York, 1986), p. 1065]. Employing a high-spatial-resolution permeable electromagnetic acoustic transducer to preferentially excite the metallization, the acoustic coupling between the metal foil and substrate may be probed. Scanning, then, provides a map of delaminations. To extend and generalize these results, the detailed generation mechanism and acoustic response of the substrate has been studied. A computer program developed previously [W. Imaino, J. Acoust. Soc. Am. Suppl. 1 80, S7 (1986)] was used to model the acoustic source. In this investigation, a finite-element calculation is used to provide a more detailed description of the acoustic behavior of the delaminated plate. The effects of source size relative to defect dimensions and acoustic properties of the substrate have been studied. The determination of the localized coupling is complicated by structural resonances of the substrate, which make single frequency measurements unfavorable. However, the analysis shows that the spectral acoustic behavior provides an indication of metallization to substrate coupling. A signal-processing algorithm based on this analysis has been formulated and will be described.

  20. Solid-state 73Ge NMR spectroscopy of simple organogermanes.

    Science.gov (United States)

    Hanson, Margaret A; Sutrisno, Andre; Terskikh, Victor V; Baines, Kim M; Huang, Yining

    2012-10-22

    Germanium-73 is an extremely challenging nucleus to examine by NMR spectroscopy due to its unfavorable NMR properties. Through the use of an ultrahigh (21.1 T) magnetic field, a systematic study of a series of simple organogermanes was carried out. In those cases for which X-ray structural data were available, correlations were drawn between the NMR parameters and structural metrics. These data were combined with DFT calculations to obtain insight into the structures of several compounds with unknown crystal structures. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Nanoscale NMR and NQR with Nitrogen Vacancy Centers

    Science.gov (United States)

    Urbach, Elana; Lovchinsky, Igor; Sanchez-Yamagishi, Javier; Choi, Soonwon; Bylinskii, Alexei; Dwyer, Bo; Andersen, Trond; Sushkov, Alex; Park, Hongkun; Lukin, Mikhail

    2016-05-01

    Nuclear quadrupole resonance (NQR) is a powerful tool which is used to detect quadrupolar interaction in nuclear spins with I > 1/2. Conventional NQR and NMR technology, however, rely on measuring magnetic fields from a macroscopic number of spins. Extending NMR and NQR techniques to the nanoscale could allow us to learn structural information about interesting materials and biomolecules. We present recent progress on using Nitrogen-Vacancy (NV) centers in diamond to perform room temperature nanoscale NMR and NQR spectroscopy on small numbers of nuclear spins in hexagonal boron nitride.

  2. NMR study of the gelation of a designed gelator.

    Science.gov (United States)

    Brand, Torsten; Nolis, Pau; Richter, Sven; Berger, Stefan

    2008-06-01

    The gelation of a designed gelator was investigated by different NMR methods, which showed a clear thermal hysteresis. Two very simple approaches for the NMR determination of the gelation point are suggested. One involves the observation of the NMR integral, and the other records the ratio of the diffusion coefficients between the gelator and the solvent. Differential behavior of the gelator protons are interpreted as a hint that a part of the gelator molecule might still be flexible as in the dissolved state. Copyright (c) 2008 John Wiley & Sons, Ltd

  3. NMR contributions to structural dynamics studies of intrinsically disordered proteins☆

    Science.gov (United States)

    Konrat, Robert

    2014-01-01

    Intrinsically disordered proteins (IDPs) are characterized by substantial conformational plasticity. Given their inherent structural flexibility X-ray crystallography is not applicable to study these proteins. In contrast, NMR spectroscopy offers unique opportunities for structural and dynamic studies of IDPs. The past two decades have witnessed significant development of NMR spectroscopy that couples advances in spin physics and chemistry with a broad range of applications. This article will summarize key advances in basic physical-chemistry and NMR methodology, outline their limitations and envision future R&D directions. PMID:24656082

  4. Room temperature chiral discrimination in paramagnetic NMR spectroscopy

    CERN Document Server

    Soncini, Alessandro

    2016-01-01

    A recently proposed theory of chiral discrimination in NMR spectroscopy based on the detection of a molecular electric polarization $\\mathbf{P}$ rotating in a plane perpendicular to the NMR magnetic field [A. D. Buckingham, J. Chem. Phys. $\\mathbf{140}$, 011103 (2014)], is here generalized to paramagnetic systems. Our theory predicts new contributions to $\\mathbf{P}$, varying as the square of the inverse temperature. Ab initio calculations for ten Dy$^{3+}$ complexes, at 293K, show that in strongly anisotropic paramagnetic molecules $\\mathbf{P}$ can be more than 1000 times larger than in diamagnetic molecules, making paramagnetic NMR chiral discrimination amenable to room temperature detection.

  5. Characterisation of triacetone triperoxide (TATP) conformers using LC-NMR.

    Science.gov (United States)

    Haroune, Nicolas; Crowson, Andrew; Campbell, Bill

    2011-06-01

    Previous studies [1,2] have reported the existence of two conformers of TATP. This study demonstrates the ability of LC-NMR to separate and characterise the individual conformers. The NMR data is consistent with the proposed structures for the two conformers. Re-equilibration can be followed by NMR and the kinetics of the process studied. Over the past decade the use of the explosive TATP in terrorist devices has increased. Therefore, the ability to analyse and characterise this material has assumed greater importance. Copyright © 2010 Forensic Science Society. All rights reserved.

  6. NMR Studies of Protein Structure and Dynamics

    Science.gov (United States)

    Li, Xiang

    Available from UMI in association with The British Library. Requires signed TDF. This thesis describes applications of 2D homonuclear NMR techniques to the study of protein structure and dynamics in solution. The sequential assignments for the 3G-residue bovine Pancreatic Polypeptide (bPP) are reported. The secondary and tertiary structure of bPP in solution has been determined from experimental NMR data. bPP has a well defined C-terminal alpha-helix and a rather ordered conformation in the N-terminal region. The two segments are joined by a turn which is poorly defined. Both the N- and the C-terminus are highly disordered. The mean solution structure of bPP is remarkably similar to the crystal structure of avian Pancreatic Polypeptide (aPP). The average conformations of most side-chains from the alpha-helix of bPP in solution are closely similar to those of aPP in the crystalline state. A large number of side-chains of bPP, however, show significant conformational averaging in solution. The 89-residue kringle domain of urokinase from both human and recombinant sources has been investigated. Sequential assignments based primarily on the recombinant sample and the determination of secondary structure are presented. Two helices have been identified; one of these corresponds to that reported for t-PA kringle 2, but does not exist in other kringles with known structures. The second helix is thus far unique to the urokinase kringle. Three antiparallel beta-sheets and three tight turns have also been identified. The tertiary fold of the molecule conforms broadly to that found for other kringles. Three regions in the urokinase kringle exhibit high local mobility; one of these, the Pro56-Pro62 segment, forms part of the proposed binding site. The other two mobile regions are the N- and C-termini which are likely to form the interfaces between the kringle and the other two domains (EGF and protease) in urokinase. The differential dynamic behaviours of the kringle and

  7. Acoustic characteristics of the water of the Bay of Bengal

    Digital Repository Service at National Institute of Oceanography (India)

    Murty, T.V.R.; Somayajulu, Y.K.; Chodankar, P.V.; Murty, C.S.

    Acoustic eigen rays (rays connecting the source and receiver) have been indentified and their turning depth, path length, travel time etc. evaluated. Acoustic intensity loss due to mean environmental conditions, vergence along acoustic rays...

  8. North Pacific Acoustic Laboratory and Deep Water Acoustics

    Science.gov (United States)

    2016-10-27

    transmission from ship stop SS500 at 500 km from the DVLA and a depth of 1000 m, 2) a tow of a CTD Chain along the path toward the Distributed Vertical Line ...limits to signal processing at long-range that are imposed by ocean processes. The long-term goal of this research is to optimize advanced signal...character of the propagation and noise fields and their impact on long- range ocean acoustic signal transmissions . Attachment 1: FY14 Annual Report

  9. Dilute Bicellar Solutions for Structural NMR Work

    Science.gov (United States)

    Struppe, Jochem; Vold, Regitze R.

    1998-12-01

    Deuterium NMR spectroscopy has been employed to characterize the concentration dependence of orientational order in DMPC/DHPC bicellar solutions with molar ratiosq= [DMPC]/[DHPC] = 3.3, 2.7, and 2.3. The stability of a discotic nematic phase can, in general, be predicted from a simple Onsager picture involving the size and concentration of the mesogenic unit, but for the bicellar solutions this model is not adequate. Specifically, macroscopic alignment is observed at total lipid concentrations well below that, 1-10% (w/w) predicted by Onsager's model. Thus the discotic nematic phase is stable to ≈3-5% (w/w) forq= 3.3-2.3, and the bicellar order is highest just before phase separation occurs at the minimum total phospholipid concentration. This implies the presence of a DHPCbic⇄ DHPCsolequilibrium in establishing bicellar size, thereby extending the range of concentrations for which alignment occurs. Bicellar morphology has been verified for a wide range of concentrations, temperatures, andq-values, but as viscosity measurements demonstrate, major morphological changes take place as the temperature is reduced below 30°C.

  10. A multinuclear static NMR study of geopolymerisation

    Energy Technology Data Exchange (ETDEWEB)

    Favier, Aurélie, E-mail: aurelie.favier@epfl.ch [Univ Paris-Est, IFSTTAR, Materials Department, 14-20 bd Newton, F-77447 Marne la Vallée Cedex 2 (France); Habert, Guillaume [Institute for Construction and Infrastructure Management, ETH Zurich, CH-8093 Zurich (Switzerland); Roussel, Nicolas [Univ Paris-Est, IFSTTAR, Materials Department, 14-20 bd Newton, F-77447 Marne la Vallée Cedex 2 (France); D' Espinose de Lacaillerie, Jean-Baptiste [Ecole Supérieure de Physique et de Chimie Indusrtrielles de la Ville de Paris (ESPCI), ParisTech, PSL Research University, Soft Matter Sciences and Engineering Laboratory SIMM, CNRS UMR 7615, 10 rue Vauquelin, F-75005 Paris (France)

    2015-09-15

    Geopolymers are inorganic binders obtained by alkali activation of aluminosilicates. While the structure of geopolymers is now well understood, the details of the geopolymerisation reaction and their impact on the rheology of the paste remain uncertain. In this work, we follow the elastic properties of a paste made with metakaolin and sodium silicate solution. After the first sharp increase of elastic modulus occurring a few hundred of seconds after mixing and related to the heterogeneous formation of an alumina–silicate gel with a molar ratio Si/Al < 4 located at the grains boundaries, we focus on the progressive increase in elastic modulus on a period of few hours during the setting of the geopolymer. In this study, we combine the study of rheological properties of the paste with {sup 23}Na, {sup 27}Al and {sup 29}Si static NMR measurement in order to better understand the origin of this second increase in elastic modulus. Our results show that, after a few hours, Al and Na evolution in the liquid phase are concomitant. This suggests the precipitation of an aluminosilicate phase where Al is in tetrahedral position and Na compensates the charge. Furthermore, Si speciation confirms this result and allows us to identify the precipitation of a product, which has a chemical composition close to the final composition of geopolymer. This study provides strong evidence for a heterogeneous formation of an aluminosilicate glass directly from the first gel and the silicate solution without the need for a reorganisation of Gel 1 into Gel 2.

  11. Airy acoustical-sheet spinner tweezers

    Science.gov (United States)

    Mitri, F. G.

    2016-09-01

    The Airy acoustical beam exhibits parabolic propagation and spatial acceleration, meaning that the propagation bending angle continuously increases before the beam trajectory reaches a critical angle where it decays after a propagation distance, without applying any external bending force. As such, it is of particular importance to investigate its properties from the standpoint of acoustical radiation force, spin torque, and particle dynamics theories, in the development of novel particle sorting techniques and acoustically mediated clearing systems. This work investigates these effects on a two-dimensional (2D) circular absorptive structure placed in the field of a nonparaxial Airy "acoustical-sheet" (i.e., finite beam in 2D), for potential applications in surface acoustic waves and acousto-fluidics. Based on the characteristics of the acoustic field, the beam is capable of manipulating the circular cylindrical fluid cross-section and guides it along a transverse or parabolic trajectory. This feature of Airy acoustical beams could lead to a unique characteristic in single-beam acoustical tweezers related to acoustical sieving, filtering, and removal of particles and cells from a section of a small channel. The analysis developed here is based on the description of the nonparaxial Airy beam using the angular spectrum decomposition of plane waves in close association with the partial-wave series expansion method in cylindrical coordinates. The numerical results demonstrate the ability of the nonparaxial Airy acoustical-sheet beam to pull, propel, or accelerate a particle along a parabolic trajectory, in addition to particle confinement in the transverse direction of wave propagation. Negative or positive radiation force and spin torque causing rotation in the clockwise or the anticlockwise direction can occur depending on the nondimensional parameter ka (where k is the wavenumber and a is the radius) and the location of the cylinder in the beam. Applications in

  12. Liquid rocket combustion chamber acoustic characterization

    Directory of Open Access Journals (Sweden)

    Cândido Magno de Souza

    2010-09-01

    Full Text Available Over the last 40 years, many solid and liquid rocket motors have experienced combustion instabilities. Among other causes, there is the interaction of acoustic modes with the combustion and/or fluid dynamic processes inside the combustion chamber. Studies have been showing that, even if less than 1% of the available energy is diverted to an acoustic mode, combustion instability can be generated. On one hand, this instability can lead to ballistic pressure changes, couple with other propulsion systems such as guidance or thrust vector control, and in the worst case, cause motor structural failure. In this case, measures, applying acoustic techniques, must be taken to correct/minimize these influences on the combustion. The combustion chamber acoustic behavior in operating conditions can be estimated by considering its behavior in room conditions. In this way, acoustic tests can be easily performed, thus identifying the cavity modes. This paper describes the procedures to characterize the acoustic behavior in the inner cavity of four different configurations of a combustion chamber. Simple analytical models are used to calculate the acoustic resonance frequencies and these results are compared with acoustic natural frequencies measured at room conditions. Some comments about the measurement procedures are done, as well as the next steps for the continuity of this research. The analytical and experimental procedures results showed good agreement. However, limitations on high frequency band as well as in the identification of specific kinds of modes indicate that numerical methods able to model the real cavity geometry and an acoustic experimental modal analysis may be necessary for a more complete analysis. Future works shall also consider the presence of passive acoustic devices such as baffles and resonators capable of introducing damping and avoiding or limiting acoustic instabilities.

  13. Acoustic surface transformation realized by acoustic-null materials using bilayer natural materials

    Science.gov (United States)

    Li, Borui; Sun, Fei; He, Sailing

    2017-11-01

    We propose a general method, known as acoustic surface transformation (AST), to design novel acoustic devices and study the realization of such devices by using naturally available materials in broadband acoustic frequencies. All devices designed by AST only need one anisotropic homogeneous acoustic-null material (ANM). We design the ANM by exploiting natural material-based metal-fluid structures and verify that by numerical simulation. Unlike traditional methods, no complicated mathematical calculations are needed. We only need to design the geometrical shapes of the input and output surfaces of the devices. The proposed method will pave a new road for future acoustic design.

  14. Reducing the dimensions of acoustic devices using anti-acoustic-null media

    Science.gov (United States)

    Li, Borui; Sun, Fei; He, Sailing

    2018-02-01

    An anti-acoustic-null medium (anti-ANM), a special homogeneous medium with anisotropic mass density, is designed by transformation acoustics (TA). Anti-ANM can greatly compress acoustic space along the direction of its main axis, where the size compression ratio is extremely large. This special feature can be utilized to reduce the geometric dimensions of classic acoustic devices. For example, the height of a parabolic acoustic reflector can be greatly reduced. We also design a brass–air structure on the basis of the effective medium theory to materialize the anti-ANM in a broadband frequency range. Numerical simulations verify the performance of the proposed anti-ANM.

  15. Cell signaling, post-translational protein modifications and NMR spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Theillet, Francois-Xavier [In-cell NMR Group, Department of NMR-Supported Structural Biology, Leibniz Institute of Molecular Pharmacology (FMP Berlin) (Germany); Smet-Nocca, Caroline [Universite Lille Nord de France, CNRS UMR 8576 (France); Liokatis, Stamatios; Thongwichian, Rossukon; Kosten, Jonas [In-cell NMR Group, Department of NMR-Supported Structural Biology, Leibniz Institute of Molecular Pharmacology (FMP Berlin) (Germany); Yoon, Mi-Kyung; Kriwacki, Richard W. [St. Jude Children' s Research Hospital, Department of Structural Biology (United States); Landrieu, Isabelle; Lippens, Guy [Universite Lille Nord de France, CNRS UMR 8576 (France); Selenko, Philipp, E-mail: selenko@fmp-berlin.de [In-cell NMR Group, Department of NMR-Supported Structural Biology, Leibniz Institute of Molecular Pharmacology (FMP Berlin) (Germany)

    2012-11-15

    Post-translationally modified proteins make up the majority of the proteome and establish, to a large part, the impressive level of functional diversity in higher, multi-cellular organisms. Most eukaryotic post-translational protein modifications (PTMs) denote reversible, covalent additions of small chemical entities such as phosphate-, acyl-, alkyl- and glycosyl-groups onto selected subsets of modifiable amino acids. In turn, these modifications induce highly specific changes in the chemical environments of individual protein residues, which are readily detected by high-resolution NMR spectroscopy. In the following, we provide a concise compendium of NMR characteristics of the main types of eukaryotic PTMs: serine, threonine, tyrosine and histidine phosphorylation, lysine acetylation, lysine and arginine methylation, and serine, threonine O-glycosylation. We further delineate the previously uncharacterized NMR properties of lysine propionylation, butyrylation, succinylation, malonylation and crotonylation, which, altogether, define an initial reference frame for comprehensive PTM studies by high-resolution NMR spectroscopy.

  16. Interfaces in polymer nanocomposites – An NMR study

    Energy Technology Data Exchange (ETDEWEB)

    Böhme, Ute; Scheler, Ulrich, E-mail: scheler@ipfdd.de [Leibniz-Institut für Polymerforschung Dresden e.V., Hohe Str. 6, 01069 Dresden (Germany)

    2016-03-09

    Nuclear Magnetic Resonance (NMR) is applied for the investigation of polymer nanocomposites. Solid-state NMR is applied to study the modification steps to compatibilize layered double hydroxides with non-polar polymers. {sup 1}H relaxation NMR gives insight on the polymer dynamics over a wide range of correlation times. For the polymer chain dynamics the transverse relaxation time T{sub 2} is most suited. In this presentation we report on two applications of T{sub 2} measurements under external mechanical stress. In a low-field system relaxation NMR studies are performed in-situ under uniaxial stress. High-temperature experiments in a Couette cell permit the investigation of the polymer dynamics in the melt under shear flow.

  17. A covariance NMR toolbox for MATLAB and OCTAVE.

    Science.gov (United States)

    Short, Timothy; Alzapiedi, Leigh; Brüschweiler, Rafael; Snyder, David

    2011-03-01

    The Covariance NMR Toolbox is a new software suite that provides a streamlined implementation of covariance-based analysis of multi-dimensional NMR data. The Covariance NMR Toolbox uses the MATLAB or, alternatively, the freely available GNU OCTAVE computer language, providing a user-friendly environment in which to apply and explore covariance techniques. Covariance methods implemented in the toolbox described here include direct and indirect covariance processing, 4D covariance, generalized indirect covariance (GIC), and Z-matrix transform. In order to provide compatibility with a wide variety of spectrometer and spectral analysis platforms, the Covariance NMR Toolbox uses the NMRPipe format for both input and output files. Additionally, datasets small enough to fit in memory are stored as arrays that can be displayed and further manipulated in a versatile manner within MATLAB or OCTAVE. Copyright © 2010 Elsevier Inc. All rights reserved.

  18. Structural, vibrational, NMR, quantum chemical, DNA binding and ...

    Indian Academy of Sciences (India)

    -one oxime (HL¹) and 3-(pyridin-2-ylmethylimino)-pentan-2-one oxime (HL²) have been synthesized and characterized by elemental analysis, IR and NMR techniques. The conformational behavior was investigated using the density functional ...

  19. NMR with Combined Antiangiogenic and Radiation Therapies - Breast Cancer

    National Research Council Canada - National Science Library

    Brown, Stephen

    2000-01-01

    The original goal of the present study was to determine optimal strategies for combining radiation and antiangiogenic therapies in spontaneous murine tumors and to evaluate the potential of Nuclear Magnetic Resonance (NMR...

  20. NMR study of hydrogen in cathodically charged Inconel 718

    Energy Technology Data Exchange (ETDEWEB)

    Raizman, A.; Barak, J.; Zamir, D. (Israel Atomic Energy Commission, Yavne. Soreq Nuclear Research Center); Eliezer, D. (Ben-Gurion Univ. of the Negev, Beersheba (Israel))

    1983-11-01

    An NMR signal of protons in cathodically charged Inconel 718 has been detected. T/sub 1/, T/sub 2/, line shift and line width have been measured. Conclusions about hydrogen behavior in Inconel have been drawn.

  1. Optical analogue of 2D heteronuclear double-quantum NMR

    CERN Document Server

    Tollerud, Jonathan

    2016-01-01

    Heteronuclear multi-quantum spectroscopy is a powerful part of the NMR toolbox, commonly used to identify specific sequences of atoms in complex pulse sequences designed to determine the structure of complex molecules, including proteins. Optical coherent multidimensional spectroscopy (CMDS) is analogous to multidimensional NMR and many of the techniques of NMR have been adapted for application in the optical regime. This has been highly successful, with CMDS being used to understand energy transfer in photosynthesis and many body effects in semiconductor nanostructures amongst many other scientific breakthroughs. Experimental challenges have, however, prevented the translation of heteronuclear multi-quantum NMR to the optical regime, where capabilities to isolate signals in otherwise congested spectra, reduce acquisition times and enable more incisive probes of multi-particle correlations and complex electronic systems would have great benefit. Here we utilise a diffraction based pulseshaper to impose the tw...

  2. International NMR-based Environmental Metabolomics Intercomparison Exercise

    Science.gov (United States)

    Several fundamental requirements must be met so that NMR-based metabolomics and the related technique of metabonomics can be formally adopted into environmental monitoring and chemical risk assessment. Here we report an intercomparison exercise which has evaluated the effectivene...

  3. NMR methods for the investigation of structure and transport

    Energy Technology Data Exchange (ETDEWEB)

    Hardy, Edme H. [Karlsruher Institut fuer Technologie (KIT), Karlsruhe (Germany). Inst. fuer Mechanische Verfahrenstechnik und Mechanik

    2012-07-01

    Extensive derivations of required fundamental relations for readers with engineering background New applications based on MRI, PGSE-NMR, and low-field NMR New concepts in quantitative data evaluation and image analysis Methods of nuclear magnetic resonance (NMR) are increasingly applied in engineering sciences. The book summarizes research in the field of chemical and process engineering performed at the Karlsruhe Institute of Technology (KIT). Fundamentals of the methods are exposed for readers with an engineering background. Applications cover the fields of mechanical process engineering (filtration, solid-liquid separation, powder mixing, rheometry), chemical process engineering (trickle-bed reactor, ceramic sponges), bioprocess engineering (biofilm growth), and food process engineering (microwave heating, emulsions). Magnetic Resonance Imaging (MRI) as well as low-field NMR are covered with notes on hardware. Emphasis is placed on quantitative data analysis and image processing. (orig.)

  4. Acoustical studies of some derivatives of 1,5-benzodiazepines formamide and tetrahydrofuran solutions at 298.15 K

    Science.gov (United States)

    Baluja, S.; Movaliya, J.; Godvani, N.

    2009-12-01

    Some derivatives of 1,5-benzodiazepines have been synthesized and characterized by TLC, IR, NMR, and Mass Spectral data. The ultrasonic velocity, density and viscosity of these synthesized compounds have been measured in dimethyl formamide and tetrahydrofuran at 298.15 K. From these experimental data, various acoustical parameters such as isentropic compressibility, intermolecular free path length, molar compressibility, Rao’s molar sound function, relaxation strength, internal pressure, free volume etc., have been calculated which helps in understanding the molecular interactions occurring in these solutions.

  5. Acoustic Microscopy at Cryogenic Temperatures.

    Science.gov (United States)

    1983-09-01

    L IIIIIrLL I~llI Illl ’.___- IImIIII...!~... 1.8 MICRO PY R[,oLUfroN uSF C HAPI NA: IN A t M I NC IA ACOUSTIC MICROSCOPY AT CRYOGENIC TEMPERATURES...ORGANIZATION NAME AND ADDRESS 10, PROGRAM ELEMENT. PROJECT, TASK Edward L. Ginzton Laboratory AREA & WORK UNfT UMBERS W.W. Hansen Laboratories of...microscope. As a follow-on to this work we are now planning to double the frequency to 8 GHz. The preliminary testing has been done and it now appears

  6. Sonochemistry and the acoustic bubble

    CERN Document Server

    Grieser, Franz; Enomoto, Naoya; Harada, Hisashi; Okitsu, Kenji; Yasui, Kyuichi

    2015-01-01

    Sonochemistry and the Acoustic Bubble provides an introduction to the way ultrasound acts on bubbles in a liquid to cause bubbles to collapse violently, leading to localized 'hot spots' in the liquid with temperatures of 5000° celcius and under pressures of several hundred atmospheres. These extreme conditions produce events such as the emission of light, sonoluminescence, with a lifetime of less than a nanosecond, and free radicals that can initiate a host of varied chemical reactions (sonochemistry) in the liquid, all at room temperature. The physics and chemistry behind the p

  7. Superhigh Temperatures and Acoustic Cavitation

    CERN Document Server

    Belyaev, V B; Miller, M B; Sermyagin, A V; Topolnikov, A S

    2003-01-01

    The experimental results on thermonuclear synthesis under acoustic cavitation have been analyzed with the account of the latest data and their discussion. The analysis testifies that this avenue of research is a very promising one. The numerical calculations of the D(d, n)^{3}He reaction rate in the deuterated acetone (C_{3}D_{6}O) under the influence of ultrasound depending on T environment temperature within the range T=249-295 K have been carried out within the framework of hydrodynamic model. The results show that it is possible to improve substantially the effect/background relationship in experiments by decreasing the fluid temperature twenty-thirty degrees below zero.

  8. Physical acoustics principles and methods

    CERN Document Server

    Mason, Warren P

    1964-01-01

    Physical Acoustics: Principles and Methods, Volume l-Part A focuses on high frequency sound waves in gases, liquids, and solids that have been proven as powerful tools in analyzing the molecular, defect, domain wall, and other types of motions. The selection first tackles wave propagation in fluids and normal solids and guided wave propagation in elongated cylinders and plates. Discussions focus on fundamentals of continuum mechanics; small-amplitude waves in a linear viscoelastic medium; representation of oscillations and waves; and special effects associated with guided elastic waves in plat

  9. OFDM for underwater acoustic communications

    CERN Document Server

    Zhou, Shengli

    2014-01-01

    A blend of introductory material and advanced signal processing and communication techniques, of critical importance to underwater system and network development This book, which is the first to describe the processing techniques central to underwater OFDM, is arranged into four distinct sections: First, it describes the characteristics of underwater acoustic channels, and stresses the difference from wireless radio channels. Then it goes over the basics of OFDM and channel coding. The second part starts with an overview of the OFDM receiver, and develops various modules for the receiver des

  10. Seismic resonances of acoustic cavities

    Science.gov (United States)

    Schneider, F. M.; Esterhazy, S.; Perugia, I.; Bokelmann, G.

    2016-12-01

    The goal of an On-Site Inspection (OSI) is to clarify at a possible testsite whether a member state of the Comprehensive nuclear Test Ban Treaty (CTBT)has violated its rules by conducting a underground nuclear test. Compared toatmospheric and underwater tests underground nuclear explosions are the mostdifficult to detect.One primary structural target for the field team during an OSI is the detectionof an underground cavity, created by underground nuclear explosions. Theapplication of seismic-resonances of the cavity for its detection has beenproposed in the CTBT by mentioning "resonance seismometry" as possibletechnique during OSIs. We modeled the interaction of a seismic wave-field withan underground cavity by a sphere filled with an acoustic medium surrounded byan elastic full space. For this setting the solution of the seismic wave-fieldcan be computed analytically. Using this approach the appearance of acousticresonances can be predicted in the theoretical calculations. Resonance peaksappear in the spectrum derived for the elastic domain surrounding the acousticcavity, which scale in width with the density of the acoustic medium. For lowdensities in the acoustic medium as for an gas-filled cavity, the spectralpeaks become very narrow and therefore hard to resolve. The resonancefrequencies, however can be correlated to the discrete set of eigenmodes of theacoustic cavity and can thus be predicted if the dimension of the cavity isknown. Origin of the resonance peaks are internal reverberations of wavescoupling in the acoustic domain and causing an echoing signal that couples outto the elastic domain again. In the gas-filled case the amplitudes in timedomain are very low.Beside theoretical considerations we seek to find real data examples fromsimilar settings. As example we analyze a 3D active seismic data set fromFelsőpetény, Hungary that has been conducted between 2012 and 2014 on behalf ofthe CTBTO. In the subsurface of this area a former clay mine is

  11. Acoustic emission methodology and application

    CERN Document Server

    Nazarchuk, Zinoviy; Serhiyenko, Oleh

    2017-01-01

    This monograph analyses in detail the physical aspects of the elastic waves radiation during deformation or fracture of materials. I presents the  methodological bases for the practical use of acoustic emission device, and describes the results of theoretical and experimental researches of evaluation of the crack growth resistance of materials, selection of the useful AE signals. The efficiency of this methodology is shown through the diagnostics of various-purpose industrial objects. The authors obtain results of experimental researches with the help of the new methods and facilities.

  12. Noninvasive detection of nanoparticle clustering by water proton NMR

    Energy Technology Data Exchange (ETDEWEB)

    Taraban, Marc B.; Truong, Huy C.; Ilavsky, Jan; DePaz, Roberto A.; Lobo, Brian; Yu, Y. Bruce

    2017-06-01

    It is shown that water proton NMR can detect uncontrolled clustering of inert nanoparticles (NPs) formulated as aqueous suspensions. The clustering of NPs causes the compartmentalization of water molecules, leading to accelerated proton spin de-coherence, and hence, much faster water transverse relaxation rates. The results suggest that water proton NMR can be used to noninvasively inspect NP products by commercial end users and researchers.

  13. Flow units from integrated WFT and NMR data

    Energy Technology Data Exchange (ETDEWEB)

    Kasap, E.; Altunbay, M.; Georgi, D.

    1997-08-01

    Reliable and continuous permeability profiles are vital as both hard and soft data required for delineating reservoir architecture. They can improve the vertical resolution of seismic data, well-to-well stratigraphic correlations, and kriging between the well locations. In conditional simulations, permeability profiles are imposed as the conditioning data. Variograms, covariance functions and other geostatistical indicators are more reliable when based on good quality permeability data. Nuclear Magnetic Resonance (NMR) logging and Wireline Formation Tests (WFT) separately generate a wealth of information, and their synthesis extends the value of this information further by providing continuous and accurate permeability profiles without increasing the cost. NMR and WFT data present a unique combination because WFTs provide discrete, in situ permeability based on fluid-flow, whilst NMR responds to the fluids in the pore space and yields effective porosity, pore-size distribution, bound and moveable fluid saturations, and permeability. The NMR permeability is derived from the T{sub 2}-distribution data. Several equations have been proposed to transform T{sub 2} data to permeability. Regardless of the transform model used, the NMR-derived permeabilities depend on interpretation parameters that may be rock specific. The objective of this study is to integrate WFT permeabilities with NMR-derived, T{sub 2} distribution-based permeabilities and thereby arrive at core quality, continuously measured permeability profiles. We outlined the procedures to integrate NMR and WFT data and applied the procedure to a field case. Finally, this study advocates the use of hydraulic unit concepts to extend the WFT-NMR derived, core quality permeabilities to uncored intervals or uncored wells.

  14. Fluid-Rock Characterization and Interactions in NMR Well Logging

    Energy Technology Data Exchange (ETDEWEB)

    Hirasaki, George J.; Mohanty, Kishore K.

    2003-02-10

    The objective of this project was to characterize the fluid properties and fluid-rock interactions which are needed for formation evaluation by NMR well logging. NMR well logging is finding wide use in formation evaluation. The formation parameters commonly estimated were porosity, permeability, and capillary bound water. Special cases include estimation of oil viscosity, residual oil saturation, location of oil/water contact, and interpretation on whether the hydrocarbon is oil or gas.

  15. Multidimensional NMR Inversion without Kronecker Products: Multilinear Inversion

    OpenAIRE

    Medellín, David; Ravi, Vivek R.; Torres-Verdín, Carlos

    2016-01-01

    Multidimensional NMR inversion using Kronecker products poses several challenges. First, kernel compression is only possible when the kernel matrices are separable, and in recent years, there has been an increasing interest in NMR sequences with non-separable kernels. Second, in three or more dimensions, the singular value decomposition is not unique; therefore kernel compression is not well-defined for higher dimensions. Without kernel compression, the Kronecker product yields matrices that ...

  16. Introducing passive acoustic filter in acoustic based condition monitoring: Motor bike piston-bore fault identification

    Science.gov (United States)

    Jena, D. P.; Panigrahi, S. N.

    2016-03-01

    Requirement of designing a sophisticated digital band-pass filter in acoustic based condition monitoring has been eliminated by introducing a passive acoustic filter in the present work. So far, no one has attempted to explore the possibility of implementing passive acoustic filters in acoustic based condition monitoring as a pre-conditioner. In order to enhance the acoustic based condition monitoring, a passive acoustic band-pass filter has been designed and deployed. Towards achieving an efficient band-pass acoustic filter, a generalized design methodology has been proposed to design and optimize the desired acoustic filter using multiple filter components in series. An appropriate objective function has been identified for genetic algorithm (GA) based optimization technique with multiple design constraints. In addition, the sturdiness of the proposed method has been demonstrated in designing a band-pass filter by using an n-branch Quincke tube, a high pass filter and multiple Helmholtz resonators. The performance of the designed acoustic band-pass filter has been shown by investigating the piston-bore defect of a motor-bike using engine noise signature. On the introducing a passive acoustic filter in acoustic based condition monitoring reveals the enhancement in machine learning based fault identification practice significantly. This is also a first attempt of its own kind.

  17. Acoustical and optical radiation pressure and the development of single beam acoustical tweezers

    Science.gov (United States)

    Thomas, Jean-Louis; Marchiano, Régis; Baresch, Diego

    2017-07-01

    Studies on radiation pressure in acoustics and optics have enriched one another and have a long common history. Acoustic radiation pressure is used for metrology, levitation, particle trapping and actuation. However, the dexterity and selectivity of single-beam optical tweezers are still to be matched with acoustical devices. Optical tweezers can trap, move and position micron size particles, biological samples or even atoms with subnanometer accuracy in three dimensions. One limitation of optical tweezers is the weak force that can be applied without thermal damage due to optical absorption. Acoustical tweezers overcome this limitation since the radiation pressure scales as the field intensity divided by the speed of propagation of the wave. However, the feasibility of single beam acoustical tweezers was demonstrated only recently. In this paper, we propose a historical review of the strong similarities but also the specificities of acoustical and optical radiation pressures, from the expression of the force to the development of single-beam acoustical tweezers.

  18. Design of acoustic devices by topology optimization

    DEFF Research Database (Denmark)

    Sigmund, Ole; Jensen, Jakob Søndergaard

    2003-01-01

    The goal of this study is to design and optimize structures and devices that are subjected to acoustic waves. Examples are acoustic lenses, sound walls, waveguides and loud speakers. We formulate the design problem as a topology optimization problem, i.e. distribute material in a design domain...

  19. Application of holography in jet acoustic studies

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    MS received 4 February 2003; revised 30 April 2004. Abstract. Source strength distribution on a jet boundary was obtained from measurements using the principle of acoustic holography. Measurements were con- ducted in an open field. Measurement of acoustic pressure on a cylindrical two- dimensional contour located ...

  20. Dynamic and Acoustic Characterisation of Automotive Wheels

    Directory of Open Access Journals (Sweden)

    Francesca Curà

    2004-01-01

    Full Text Available The subject of this paper is the dynamic and acoustic characterisation of an automotive wheel. In particular, an experimental research activity previously performed by the authors about the dynamic behaviour of automotive wheels has been extended to the acoustic field.

  1. Acoustic quality and sound insulation between dwellings

    DEFF Research Database (Denmark)

    Rindel, Jens Holger

    1998-01-01

    to another, however, several of the results show a slope around 4 % per dB. The results may be used to evaluate the acoustic quality level of a certain set of sound insulation requirements, or they may be used as a basis for specifying the desired acoustic quality of future buildings...

  2. Acoustic cymbal performance under hydrostatic pressure

    Science.gov (United States)

    Jenne, Kirk E.; Huang, Dehua; Howarth, Thomas R.

    2004-05-01

    Continual awareness about the need to develop light-weight, low-volume, broadband, underwater acoustic projector and receive arrays that perform consistently in diverse environments is evident in recent Navy acoustic system initiatives. Acoustic cymbals, so named for resemblance to the percussive musical instruments, are miniature flextensional transducers that may perhaps meet the performance criteria for consistent performance under hydrostatic pressure after modifications in the design. These acoustic cymbals consist of a piezoceramic disk (or ring) bonded to two opposing cymbal-shaped metal shells. Operating as mechanical transformers, the two metal shells convert the large generative force inherently within the disk's radial mode into increased volume displacement at the metal shell surface to obtain volume displacement that translates into usable source levels and/or sensitivities at sonar frequencies in a relatively broad band. The air-backed design for standard acoustic cymbal transducers presents a barrier to deepwater applications. A new acoustic cymbal design for high-pressure applications will be presented for the first time. This practical pressure compensation is designed to diminish the effects of hydrostatic pressure to maintain consistent acoustic cymbal performance. Transmit and receive performance data, determined at the Naval Undersea Warfare Center's (NUWC) Acoustic Pressure Tank Facility (APTF), is presented.

  3. Acoustic quality and sound insulation between dwellings

    DEFF Research Database (Denmark)

    Rindel, Jens Holger

    1999-01-01

    to another, however, several of the results show a slope around 4 % per dB. The results may be used to evaluate the acoustic quality level of a certain set of sound insulation requirements, or they may be used as a basis for specifying the desired acoustic quality of future buildings....

  4. an assessment of the acoustic adaptation hypothesis

    African Journals Online (AJOL)

    Song is critical to territory defence, mate attraction, and both species and individual recognition. According to the Acoustic Adaptation Hypothesis (AAH), habitat structure may exercise a selective force on vocal evolution such that song evolves to minimise the degradation and attenuation of acoustic signals in the particular ...

  5. Room acoustic properties of concert halls

    DEFF Research Database (Denmark)

    Gade, Anders Christian

    1996-01-01

    A large database of values of various room acoustic parameters has provided the basis for statistical analyses of how and how much the acoustic properties of concert halls are influenced by their size, shape, and absorption area (as deduced from measured reverberation time). The data have been...

  6. Acoustic power measurements of oscillating flames

    NARCIS (Netherlands)

    Valk, M.

    1981-01-01

    The acoustic power of an oscillating flame is measured. A turbulent premixed propane/air flame is situated near a pressure antinode of a standing wave in a laboratory combustion chamber. This standing wave is generated by a piston. The fluctuating heat release of the flame will supply acoustic power

  7. Measuring aeolian sand transport using acoustic sensors

    NARCIS (Netherlands)

    Poortinga, Ate; Rheenen, van Hans; Ellis, J.T.; Sherman, D.J.

    2015-01-01

    Acoustic sensors are frequently used to measure aeolian saltation. Different approaches are used to process the signals from these instruments. The goal of this paper is to describe and discuss a method to measure aeolian saltation with acoustic sensors. In a laboratory experiment, we measured

  8. Applications of acoustics in insect pest management

    Science.gov (United States)

    Acoustic technology has been applied for many years in studies of insect communication and in the monitoring of calling-insect population levels, geographic distributions, and diversity, as well as in the detection of cryptic insects in soil, wood, container crops, and stored products. Acoustic devi...

  9. An acoustical model based monitoring network

    NARCIS (Netherlands)

    Wessels, P.W.; Basten, T.G.H.; Eerden, F.J.M. van der

    2010-01-01

    In this paper the approach for an acoustical model based monitoring network is demonstrated. This network is capable of reconstructing a noise map, based on the combination of measured sound levels and an acoustic model of the area. By pre-calculating the sound attenuation within the network the

  10. On Collisionless Damping of Ion Acoustic Waves

    DEFF Research Database (Denmark)

    Jensen, Vagn Orla; Petersen, P.I.

    1973-01-01

    Exact theoretical treatments show that the damping of ion acoustic waves in collisionless plasmas does not vanish when the derivative of the undisturbed distribution function at the phase velocity equals zero.......Exact theoretical treatments show that the damping of ion acoustic waves in collisionless plasmas does not vanish when the derivative of the undisturbed distribution function at the phase velocity equals zero....

  11. The Microflown, an acoustic particle velocity sensor

    NARCIS (Netherlands)

    de Bree, H.E.

    2003-01-01

    The Microflown is an acoustic sensor directly measuring particle velocity instead of sound pressure, which is usually measured by conventional microphones. Since its invention in 1994 it is mostly used for measurement purposes (broadband1D and 3D-sound intensity measurement and acoustic impedance).

  12. Solidly Mounted Resonator with Optimized Acoustic Reflector

    NARCIS (Netherlands)

    Jose, Sumy; Jansman, Andreas; Hueting, Raymond Josephus Engelbart

    2009-01-01

    The quality factor (Q) of the Solidly Mounted Resonator is limited by acoustic losses caused by waves leaking through the mirror stack. Traditionally employed acoustic mirror reflects only longitudinal waves and not shear waves. Starting with the stop-band theory and the principle of spacer layers

  13. Acoustic-Emission Weld-Penetration Monitor

    Science.gov (United States)

    Maram, J.; Collins, J.

    1986-01-01

    Weld penetration monitored by detection of high-frequency acoustic emissions produced by advancing weld pool as it melts and solidifies in workpiece. Acoustic emission from TIG butt weld measured with 300-kHz resonant transducer. Rise in emission level coincides with cessation of weld penetration due to sudden reduction in welding current. Such monitoring applied to control of automated and robotic welders.

  14. Acoustic sorting models for improved log segregation

    Science.gov (United States)

    Xiping Wang; Steve Verrill; Eini Lowell; Robert J. Ross; Vicki L. Herian

    2013-01-01

    In this study, we examined three individual log measures (acoustic velocity, log diameter, and log vertical position in a tree) for their ability to predict average modulus of elasticity (MOE) and grade yield of structural lumber obtained from Douglas-fir (Pseudotsuga menziesii [Mirb. Franco]) logs. We found that log acoustic velocity only had a...

  15. Eliminating transducer distortion in acoustic measurements

    DEFF Research Database (Denmark)

    Agerkvist, Finn T.; Torras Rosell, Antoni; McWalter, Richard Ian

    2014-01-01

    This paper investigates the in uence of nonlinear components that contaminate the linear response of acoustic transducer, and presents a method for eliminating the in uence of nonlinearities in acoustic measurements. The method is evaluated on simulated as well as experimental data, and is shown...

  16. Acoustic Pattern Recognition on Android Devices

    DEFF Research Database (Denmark)

    Møller, Maiken Bjerg; Gaarsdal, Jesper; Steen, Kim Arild

    2013-01-01

    an Android application developed for acoustic pattern recognition of bird species. The acoustic data is recorded using a built-in microphone, and pattern recognition is performed on the device, requiring no network connection. The algorithm is implemented in C++ as a native Android module and the OpenCV...

  17. Acoustic characteristics of Danish infant directed speech

    DEFF Research Database (Denmark)

    Bohn, Ocke-Schwen

    2013-01-01

    Danish presents several challenges for language learners, such as a very densely packed upper portion of the acoustic vowel space, and a sibilant contrast that is acoustically less distinct than in e.g. English. The present study examined whether Danish caregivers enhance Danish contrasts when sp......'s receptive vocabulary knowledge....

  18. Auditory modelling for assessing room acoustics

    NARCIS (Netherlands)

    Van Dorp Schuitman, J.

    2011-01-01

    The acoustics of a concert hall, or any other room, are generally assessed by measuring room impulse responses for one or multiple source and receiver location(s). From these responses, objective parameters can be determined that should be related to various perceptual attributes of room acoustics.

  19. Air Coupled Acoustic Thermography (ACAT) Inspection Technique

    Science.gov (United States)

    Zalameda, Joseph; Winfree, William P.; Yost, William T.

    2007-01-01

    The scope of this effort is to determine the viability of a new heating technique using a noncontact acoustic excitation source. Because of low coupling between air and the structure, a synchronous detection method is employed. Any reduction in the out of plane stiffness improves the acoustic coupling efficiency and as a result, defective areas have an increase in temperature relative to the surrounding area. Hence a new measurement system, based on air-coupled acoustic energy and synchronous detection is presented. An analytical model of a clamped circular plate is given, experimentally tested, and verified. Repeatability confirms the technique with a measurement uncertainty of plus or minus 6.2 percent. The range of frequencies used was 800-2,000 Hertz. Acoustic excitation and consequent thermal detection of flaws in a helicopter blade is examined and results indicate that air coupled acoustic excitation enables the detection of core damage in sandwich honeycomb structures.

  20. Auditorium Acoustics From Past to Present

    Directory of Open Access Journals (Sweden)

    Kabiru Maishanu

    2017-01-01

    Full Text Available The main aim of this paper is to identify how acoustics where generally achieve in auditoriums base on the method, technics and the materials been used. This paper will discuss the transition over time. It will cover how the design began from the past (Roman, Greek baroque, renaissance periods to the present (twentieth century. The paper will further discuss some case studies which are from different periods. The selection of the case study was based on their excellent acoustics qualities of the spaces. It will provide better understanding on how acoustics solution where been achieve in auditoriums/theaters from the past to the present. Finally, the paper will point out some major benefits of using acoustics in auditoriums and also discuss on what causes poor quality sound in the present auditoriums and then suggest the use flat panels technology and line-stone material as it has great impact in in achieving good and qualitative acoustics in the past.

  1. 30th International Acoustical Imaging Symposium

    CERN Document Server

    Jones, Joie; Lee, Hua

    2011-01-01

    The International Symposium on Acoustical Imaging is a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. This interdisciplinary Symposium has been taking place every two years since 1968. In the course of the years the proceedings volumes in the Acoustical Imaging Series have become a reference for cutting-edge research in the field. In 2009 the 30th International Symposium on Acoustical Imaging was held in Monterey, CA, USA, March 1-4. Offering both a broad perspective on the state-of-the-art as well as  in-depth research contributions by the specialists in the field, this Volume 30 in the Series contains an excellent collection of forty three papers presented in five major categories: Biomedical Imaging Acoustic Microscopy Non-Destructive Evaluation Systems Analysis Signal Analysis and Image Processing Audience Researchers in medical imaging and biomedical instrumentation experts.

  2. Worship space acoustics 3 decades of design

    CERN Document Server

    Ryherd, Erica; Ronsse, Lauren

    2016-01-01

    This book takes the reader on a wide-ranging tour through churches, synagogues, mosques, and other worship spaces designed during the past 30 years. The book begins with a series of essays on topics ranging from the soundscape of worship spaces to ecclesiastical design at the turn of the 21st Century. Perspective pieces from an architect, audio designer, music director, and worship space owner are also included. The core of the book presents the acoustical and architectural design of a wide variety of individual worship space venues. Acoustical consulting firms, architects, and worship space designers from across the world contributed their recent innovative works in the area of worship space acoustics. The contributions include detailed renderings and architectural drawings, as well as informative acoustic data graphs and evocative descriptions of the spaces. Filled with beautiful photography and fascinating modern design, this book is a must-read for anyone interested in religious architecture, acoustical d...

  3. International Conference on Acoustics and Vibration

    CERN Document Server

    Chaari, Fakher; Walha, Lasaad; Abdennadher, Moez; Abbes, Mohamed; Haddar, Mohamed

    2017-01-01

    The book provides readers with a snapshot of recent research and industrial trends in field of industrial acoustics and vibration. Each chapter, accepted after a rigorous peer-review process, reports on a selected, original piece of work presented and discussed at International Conference on Acoustics and Vibration (ICAV2016), which was organized by the Tunisian Association of Industrial Acoustics and Vibration (ATAVI) and held March 21-23, in Hammamet, Tunisia. The contributions, mainly written by north African authors, covers advances in both theory and practice in a variety of subfields, such as: smart materials and structures; fluid-structure interaction; structural acoustics as well as computational vibro-acoustics and numerical methods. Further topics include: engines control, noise identification, robust design, flow-induced vibration and many others.This book provides a valuable resource for both academics and professionals dealing with diverse issues in applied mechanics. By combining advanced theori...

  4. On architectural acoustic design using computer simulation

    DEFF Research Database (Denmark)

    Schmidt, Anne Marie Due; Kirkegaard, Poul Henning

    2004-01-01

    acoustic design process. The emphasis is put on the first three out of five phases in the working process of the architect and a case study is carried out in which each phase is represented by typical results ? as exemplified with reference to the design of Bagsværd Church by Jørn Utzon. The paper...... discusses the advantages and disadvantages of the programme in each phase compared to the works of architects not using acoustic simulation programmes. The conclusion of the paper is that the application of acoustic simulation programs is most beneficial in the last of three phases but an application...... properties prior to the actual construction of a building. With the right tools applied, acoustic design can become an integral part of the architectural design process. The aim of this paper is to investigate the field of application that an acoustic simulation programme can have during an architectural...

  5. On Architectural Acoustics Design using Computer Simulation

    DEFF Research Database (Denmark)

    Schmidt, Anne Marie Due; Kirkegaard, Poul Henning

    2004-01-01

    room acoustic simulation programs it is now possible to subjectively analyze and evaluate acoustic properties prior to the actual construction of a facility. With the right tools applied, the acoustic design can become an integrated part of the architectural design process. The aim of the present paper...... is to investigate the field of application an acoustic simulation program can have during an architectural acoustics design process. A case study is carried out in order to represent the iterative working process of an architect. The working process is divided into five phases and represented by typical results...... in each phase ? exemplified by Bagsværd Church by Jørn Utzon - and a description of which information would be beneficial to progress in the work. Among other things the applicability as a tool giving inspiration for finding forms of structures and rooms for an architect compared with an architect without...

  6. Acoustic rainbow trapping by coiling up space

    KAUST Repository

    Ni, Xu

    2014-11-13

    We numerically realize the acoustic rainbow trapping effect by tapping an air waveguide with space-coiling metamaterials. Due to the high refractive-index of the space-coiling metamaterials, our device is more compact compared to the reported trapped-rainbow devices. A numerical model utilizing effective parameters is also calculated, whose results are consistent well with the direct numerical simulation of space-coiling structure. Moreover, such device with the capability of dropping different frequency components of a broadband incident temporal acoustic signal into different channels can function as an acoustic wavelength division de-multiplexer. These results may have potential applications in acoustic device design such as an acoustic filter and an artificial cochlea.

  7. Microfabricated bulk wave acoustic bandgap device

    Science.gov (United States)

    Olsson, Roy H.; El-Kady, Ihab F.; McCormick, Frederick; Fleming, James G.; Fleming, Carol

    2010-06-08

    A microfabricated bulk wave acoustic bandgap device comprises a periodic two-dimensional array of scatterers embedded within the matrix material membrane, wherein the scatterer material has a density and/or elastic constant that is different than the matrix material and wherein the periodicity of the array causes destructive interference of the acoustic wave within an acoustic bandgap. The membrane can be suspended above a substrate by an air or vacuum gap to provide acoustic isolation from the substrate. The device can be fabricated using microelectromechanical systems (MEMS) technologies. Such microfabricated bulk wave phononic bandgap devices are useful for acoustic isolation in the ultrasonic, VHF, or UHF regime (i.e., frequencies of order 1 MHz to 10 GHz and higher, and lattice constants of order 100 .mu.m or less).

  8. Synthesis of amino acid block-copolymer imprinted chiral mesoporous silica and its acoustically-induced optical Kerr effects

    Energy Technology Data Exchange (ETDEWEB)

    Paik, Pradip, E-mail: pradip.paik@gmail.com [Department of Materials Engineering and Nanoscience and Technology, School of Engineering Sciences and Technology, University of Hyderabad, Central University P.O., Gachibowli, Hyderabad 500046, AP (India); Institute for Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, 52900 (Israel); Mastai, Yitzhak, E-mail: mastai@mail.biu.ac.il [Institute for Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, 52900 (Israel); Kityk, Iwan; Rakus, Piort [Electrical Engineering Department, Czestochowa University Technology, Armii Krajowej 17, Czestochowa (Poland); Gedanken, Aharon, E-mail: gedanken@mail.biu.ac.il [Institute for Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, 52900 (Israel)

    2012-08-15

    Chiral mesoporous SiO{sub 2} (CMS) have been synthesized and studied the Acoustically-Induced Optical Kerr Effects (AIOKE) and the results have been compared with non-chiral mesoporous silica. The CMS with controllable pore sizes (of {approx}3 nm) and high surface areas of ca. 650 m{sup 2}g{sup -1} was synthesized by mimicking the intrinsic chirality of the amino acid block copolymers. The chiral mesoporous materials were characterized through HRTEM, BET, small-angle XRD, {sup 29}Si-NMR and circular dichroism. AIOKE measurements have been performed using an Er:glass 20 ns laser with a 10 Hz frequency repetition. The optimal AIOKE results of the CMS were achieved for 9.7% of the chromophore in the matrices. We found that the AIOKE for the CMS mimicked with chiral block copolymers is quite high compared to the non-chiral SiO{sub 2}. A difference in AIOKE for these two compounds is observed, enabling CMS that can be used for the design of the acoustically-operated quantum electronic devices. - Graphical abstract: Novel chiral mesoporous SiO{sub 2} (CMS) is showing Acoustically-Induced Optical Kerr Effects (AIOKE). Different in AIOKE of two mesoporous materials is observed, enabling CMS can be used for the design of the acoustically-operated quantum electronic devices.Highlights: Black-Right-Pointing-Pointer Chiral mesoporous SiO{sub 2} (CMS) synthesized with amino acid block copolymers. Black-Right-Pointing-Pointer The Acoustically-induced Optical Kerr Effects (AIOKE) of chiral mesoporous SiO{sub 2} studied. Black-Right-Pointing-Pointer AIOKE very high for CMS compared to non chiral SiO{sub 2}. Black-Right-Pointing-Pointer CMS can be used in acoustically-operated quantum electronic devices.

  9. Method development in quantitative NMR towards metrologically traceable organic certified reference materials used as (31)P qNMR standards.

    Science.gov (United States)

    Weber, Michael; Hellriegel, Christine; Rueck, Alexander; Wuethrich, Juerg; Jenks, Peter; Obkircher, Markus

    2015-04-01

    Quantitative nuclear magnetic resonance (qNMR) spectroscopy is employed by an increasing number of analytical and industrial laboratories for the assignment of content and quantitative determination of impurities. Within the last few years, it was demonstrated that (1)H qNMR can be performed with high accuracy leading to measurement uncertainties below 1 % relative. It was even demonstrated that the combination of (1)H qNMR with metrological weighing can lead to measurement uncertainties below 0.1 % when highly pure substances are used. Although qNMR reference standards are already available as certified reference materials (CRM) providing traceability on the basis of (1)H qNMR experiments, there is an increasing demand for purity assays on phosphorylated organic compounds and metabolites requiring CRM for quantification by (31)P qNMR. Unfortunately, the number of available primary phosphorus standards is limited to a few inorganic CRM which only can be used for the analysis of water-soluble analytes but fail when organic solvents must be employed. This paper presents the concept of value assignment by (31)P qNMR measurements for the development of CRM and describes different approaches to establish traceability to primary Standard Reference Material from the National Institute of Standards and Technology (NIST SRM). Phosphonoacetic acid is analyzed as a water-soluble CRM candidate, whereas triphenyl phosphate is a good candidate for the use as qNMR reference material in organic solvents. These substances contain both nuclei, (1)H and (31)P, and the concept is to show that it is possible to indirectly quantify a potential phosphorus standard via its protons using (1)H qNMR. The same standard with its assigned purity can then be used for the quantification of an analyte via its phosphorus using (31)P qNMR. For the validation of the concept, triphenyl phosphate and phosphonoacetic acid have been used as (31)P qNMR standards to determine the purity of the analyte

  10. Millimeter waves: acoustic and electromagnetic.

    Science.gov (United States)

    Ziskin, Marvin C

    2013-01-01

    This article is the presentation I gave at the D'Arsonval Award Ceremony on June 14, 2011 at the Bioelectromagnetics Society Annual Meeting in Halifax, Nova Scotia. It summarizes my research activities in acoustic and electromagnetic millimeter waves over the past 47 years. My earliest research involved acoustic millimeter waves, with a special interest in diagnostic ultrasound imaging and its safety. For the last 21 years my research expanded to include electromagnetic millimeter waves, with a special interest in the mechanisms underlying millimeter wave therapy. Millimeter wave therapy has been widely used in the former Soviet Union with great reported success for many diseases, but is virtually unknown to Western physicians. I and the very capable members of my laboratory were able to demonstrate that the local exposure of skin to low intensity millimeter waves caused the release of endogenous opioids, and the transport of these agents by blood flow to all parts of the body resulted in pain relief and other beneficial effects. Copyright © 2012 Wiley Periodicals, Inc.

  11. Acoustic wave coupled magnetoelectric effect

    Energy Technology Data Exchange (ETDEWEB)

    Gao, J.S. [Institute of information Engineering, Suqian College, Suqian 223800 (China); Magnetoelectronic Laboratory, Nanjing Normal University, Nanjing 210023 (China); Zhang, N., E-mail: zhangning@njnu.edu.cn [Magnetoelectronic Laboratory, Nanjing Normal University, Nanjing 210023 (China)

    2016-07-15

    Magnetoelectric (ME) coupling by acoustic waveguide was developed. Longitudinal and transversal ME effects of larger than 44 and 6 (V cm{sup −1} Oe{sup −1}) were obtained with the waveguide-coupled ME device, respectively. Several resonant points were observed in the range of frequency lower than 47 kHz. Analysis showed that the standing waves in the waveguide were responsible for those resonances. The frequency and size dependence of the ME effects were investigated. A resonant condition about the geometrical size of the waveguide was obtained. Theory and experiments showed the resonant frequencies were closely influenced by the diameter and length of the waveguide. A series of double-peak curves of longitudinal magnetoelectric response were obtained, and their significance was discussed initially. - Highlights: • Magnetoelectric (ME) coupling by acoustic waveguide was developed. • The frequency and size dependence of the ME effects were investigated. • A resonant condition about the geometrical size of the waveguide was obtained. • A series of double-peak curves of longitudinal magnetoelectric response were obtained, and their significance was discussed initially.

  12. Proton NMR relaxation in hydrous melts

    Energy Technology Data Exchange (ETDEWEB)

    Braunstein, J.; Bacarella, A.L.; Benjamin, B.M.; Brown, L.L.; Girard, C.

    1976-01-01

    Pulse and continuous wave NMR measurements are reported for protons in hydrous melts of calcium nitrate at temperatures between -4 and 120/sup 0/C. Although measured in different temperature ranges, spin-lattice (T/sub 1/) and spin-spin (T/sub 2/) relaxation times appear to be nearly equal to each other and proportional to the self-diffusion coefficients of solute metal cations such as Cd/sup 2 +/. At temperatures near 50/sup 0/C, mean Arrhenius coefficients ..delta.. H/sub T/sub 1// (kcal/mol) are 7.9, 7.3, and 4.8, respectively, for melts containing 2.8, 4.0, and 8.0 moles of water per mole of calcium nitrate, compared to 4.6 kcal/mol for pure water. Temperature dependence of T/sub 1/ and T/sub 2/ in Ca(NO/sub 3/)/sub 2/-2.8 H/sub 2/O between -4 and 120/sup 0/C are non-Arrhenius and can be represented by a Fulcher-type equation with a ''zero mobility temperature'' (T/sub 0/) of 225/sup 0/K, close to the value of T/sub 0/ for solute diffusion, electrical conductance and viscosity. Resolution of the relaxation rates into correlation times for intramolecular (rotational) and intermolecular (translational) diffusional motion is discussed in terms of the Bloembergen-Purcell-Pound and more recent models for dipolar relaxation. (auth)

  13. Noninvasive testing of art and cultural heritage by mobile NMR.

    Science.gov (United States)

    Blümich, Bernhard; Casanova, Federico; Perlo, Juan; Presciutti, Federica; Anselmi, Chiara; Doherty, Brenda

    2010-06-15

    Nuclear magnetic resonance (NMR) has many applications in science, medicine, and technology. Conventional instrumentation is large and expensive, however, because superconducting magnets offer maximum sensitivity. Yet NMR devices can also be small and inexpensive if permanent magnets are used, and samples need not be placed within the magnet but can be examined externally in the stray magnetic field. Mobile stray-field NMR is a method of growing interest for nondestructive testing of a diverse range of materials and processes. A well-known stray-field sensor is the commercially available NMR-MOUSE, which is small and can readily be carried to an object to be studied. In this Account, we describe mobile stray-field NMR, with particular attention to its use in analyzing objects of cultural heritage. The most common data recorded are relaxation measurements of (1)H because the proton is the most sensitive NMR nucleus, and relaxation can be measured despite the inhomogeneous magnetic field that typically accompanies a simple magnet design. Through NMR relaxation, the state of matter can be analyzed locally, and the signal amplitude gives the proton density. A variety of stray-field sensors have been designed. Small devices weighing less than a kilogram have a shallow penetration depth of just a few millimeters and a resolution of a few micrometers. Access to greater depths requires larger sensors that may weigh 30 kg or more. The use of these sensors is illustrated by selected examples, including examinations of (i) the stratigraphy of master paintings, (ii) binder aging, (iii) the deterioration of paper, (iv) wood density in master violins, (v) the moisture content and moisture profiles in walls covered with paintings and mosaics, and (vi) the evolution of stone conservation treatments. The NMR data provide unique information to the conservator on the state of the object--including past conservation measures. The use of mobile NMR remains relatively new, expanding

  14. Impact of Acoustic Standing Waves on Structural Responses: Reverberant Acoustic Testing (RAT) vs. Direct Field Acoustic Testing (DFAT)

    Science.gov (United States)

    Kolaini, Ali R.; Doty, Benjamin; Chang, Zensheu

    2012-01-01

    Loudspeakers have been used for acoustic qualification of spacecraft, reflectors, solar panels, and other acoustically responsive structures for more than a decade. Limited measurements from some of the recent speaker tests used to qualify flight hardware have indicated significant spatial variation of the acoustic field within the test volume. Also structural responses have been reported to differ when similar tests were performed using reverberant chambers. To address the impact of non-uniform acoustic field on structural responses, a series of acoustic tests were performed using a flat panel and a 3-ft cylinder exposed to the field controlled by speakers and repeated in a reverberant chamber. The speaker testing was performed using multi-input-single-output (MISO) and multi-input-multi-output (MIMO) control schemes with and without the test articles. In this paper the spatial variation of the acoustic field due to acoustic standing waves and their impacts on the structural responses in RAT and DFAT (both using MISO and MIMO controls for DFAT) are discussed in some detail.

  15. Accurate, fully-automated NMR spectral profiling for metabolomics.

    Science.gov (United States)

    Ravanbakhsh, Siamak; Liu, Philip; Bjorndahl, Trent C; Bjordahl, Trent C; Mandal, Rupasri; Grant, Jason R; Wilson, Michael; Eisner, Roman; Sinelnikov, Igor; Hu, Xiaoyu; Luchinat, Claudio; Greiner, Russell; Wishart, David S

    2015-01-01

    Many diseases cause significant changes to the concentrations of small molecules (a.k.a. metabolites) that appear in a person's biofluids, which means such diseases can often be readily detected from a person's "metabolic profile"-i.e., the list of concentrations of those metabolites. This information can be extracted from a biofluids Nuclear Magnetic Resonance (NMR) spectrum. However, due to its complexity, NMR spectral profiling has remained manual, resulting in slow, expensive and error-prone procedures that have hindered clinical and industrial adoption of metabolomics via NMR. This paper presents a system, BAYESIL, which can quickly, accurately, and autonomously produce a person's metabolic profile. Given a 1D 1H NMR spectrum of a complex biofluid (specifically serum or cerebrospinal fluid), BAYESIL can automatically determine the metabolic profile. This requires first performing several spectral processing steps, then matching the resulting spectrum against a reference compound library, which contains the "signatures" of each relevant metabolite. BAYESIL views spectral matching as an inference problem within a probabilistic graphical model that rapidly approximates the most probable metabolic profile. Our extensive studies on a diverse set of complex mixtures including real biological samples (serum and CSF), defined mixtures and realistic computer generated spectra; involving > 50 compounds, show that BAYESIL can autonomously find the concentration of NMR-detectable metabolites accurately (~ 90% correct identification and ~ 10% quantification error), in less than 5 minutes on a single CPU. These results demonstrate that BAYESIL is the first fully-automatic publicly-accessible system that provides quantitative NMR spectral profiling effectively-with an accuracy on these biofluids that meets or exceeds the performance of trained experts. We anticipate this tool will usher in high-throughput metabolomics and enable a wealth of new applications of NMR in

  16. Accurate, fully-automated NMR spectral profiling for metabolomics.

    Directory of Open Access Journals (Sweden)

    Siamak Ravanbakhsh

    Full Text Available Many diseases cause significant changes to the concentrations of small molecules (a.k.a. metabolites that appear in a person's biofluids, which means such diseases can often be readily detected from a person's "metabolic profile"-i.e., the list of concentrations of those metabolites. This information can be extracted from a biofluids Nuclear Magnetic Resonance (NMR spectrum. However, due to its complexity, NMR spectral profiling has remained manual, resulting in slow, expensive and error-prone procedures that have hindered clinical and industrial adoption of metabolomics via NMR. This paper presents a system, BAYESIL, which can quickly, accurately, and autonomously produce a person's metabolic profile. Given a 1D 1H NMR spectrum of a complex biofluid (specifically serum or cerebrospinal fluid, BAYESIL can automatically determine the metabolic profile. This requires first performing several spectral processing steps, then matching the resulting spectrum against a reference compound library, which contains the "signatures" of each relevant metabolite. BAYESIL views spectral matching as an inference problem within a probabilistic graphical model that rapidly approximates the most probable metabolic profile. Our extensive studies on a diverse set of complex mixtures including real biological samples (serum and CSF, defined mixtures and realistic computer generated spectra; involving > 50 compounds, show that BAYESIL can autonomously find the concentration of NMR-detectable metabolites accurately (~ 90% correct identification and ~ 10% quantification error, in less than 5 minutes on a single CPU. These results demonstrate that BAYESIL is the first fully-automatic publicly-accessible system that provides quantitative NMR spectral profiling effectively-with an accuracy on these biofluids that meets or exceeds the performance of trained experts. We anticipate this tool will usher in high-throughput metabolomics and enable a wealth of new applications of

  17. 1H-NMR, 1H-NMR T2-edited, and 2D-NMR in bipolar disorder metabolic profiling.

    Science.gov (United States)

    Sethi, Sumit; Pedrini, Mariana; Rizzo, Lucas B; Zeni-Graiff, Maiara; Mas, Caroline Dal; Cassinelli, Ana Cláudia; Noto, Mariane N; Asevedo, Elson; Cordeiro, Quirino; Pontes, João G M; Brasil, Antonio J M; Lacerda, Acioly; Hayashi, Mirian A F; Poppi, Ronei; Tasic, Ljubica; Brietzke, Elisa

    2017-12-01

    The objective of this study was to identify molecular alterations in the human blood serum related to bipolar disorder, using nuclear magnetic resonance (NMR) spectroscopy and chemometrics. Metabolomic profiling, employing 1H-NMR, 1H-NMR T2-edited, and 2D-NMR spectroscopy and chemometrics of human blood serum samples from patients with bipolar disorder (n = 26) compared with healthy volunteers (n = 50) was performed. The investigated groups presented distinct metabolic profiles, in which the main differential metabolites found in the serum sample of bipolar disorder patients compared with those from controls were lipids, lipid metabolism-related molecules (choline, myo-inositol), and some amino acids (N-acetyl-L-phenyl alanine, N-acetyl-L-aspartyl-L-glutamic acid, L-glutamine). In addition, amygdalin, α-ketoglutaric acid, and lipoamide, among other compounds, were also present or were significantly altered in the serum of bipolar disorder patients. The data presented herein suggest that some of these metabolites differentially distributed between the groups studied may be directly related to the bipolar disorder pathophysiology. The strategy employed here showed significant potential for exploring pathophysiological features and molecular pathways involved in bipolar disorder. Thus, our findings may contribute to pave the way for future studies aiming at identifying important potential biomarkers for bipolar disorder diagnosis or progression follow-up.

  18. Real-time virtual room acoustic simulation

    Science.gov (United States)

    Carneal, James P.; Johnson, Jan; Johnson, Troge; Johnson, Marty

    2003-10-01

    A realistic virtual room acoustic simulation has been implemented on a PC-based computer in near real-time. Room acoustics are calculated by the image source method using realistic absorption coefficients for a variety of realistic surfaces and programmed in MATLAB. The resulting impulse response filters are then applied in near real-time using fast convolution DSP techniques using data being read from a CD-ROM. The system was implemented in a virtual acoustic room facility. Optimizations have been performed to retain the realistic virtual room effect while minimizing computations through limited psycho-acoustic testing. In general, realistic anechoic to reverberant virtual rooms have been re-created with six 8192 coefficient filters. To provide realistic simulations, special care must be taken to accurately reproduce the low frequency acoustics. Since the virtual room acoustic facility was not totally anechoic (as are most anechoic chambers), inverse filters were applied to compensate for over-amplified acoustics at frequencies below 350 Hz.

  19. Material fabrication using acoustic radiation forces

    Science.gov (United States)

    Sinha, Naveen N.; Sinha, Dipen N.; Goddard, Gregory Russ

    2015-12-01

    Apparatus and methods for using acoustic radiation forces to order particles suspended in a host liquid are described. The particles may range in size from nanometers to millimeters, and may have any shape. The suspension is placed in an acoustic resonator cavity, and acoustical energy is supplied thereto using acoustic transducers. The resulting pattern may be fixed by using a solidifiable host liquid, forming thereby a solid material. Patterns may be quickly generated; typical times ranging from a few seconds to a few minutes. In a one-dimensional arrangement, parallel layers of particles are formed. With two and three dimensional transducer arrangements, more complex particle configurations are possible since different standing-wave patterns may be generated in the resonator. Fabrication of periodic structures, such as metamaterials, having periods tunable by varying the frequency of the acoustic waves, on surfaces or in bulk volume using acoustic radiation forces, provides great flexibility in the creation of new materials. Periodicities may range from millimeters to sub-micron distances, covering a large portion of the range for optical and acoustical metamaterials.

  20. International Space Station Acoustics - A Status Report

    Science.gov (United States)

    Allen, Christopher S.

    2015-01-01

    It is important to control acoustic noise aboard the International Space Station (ISS) to provide a satisfactory environment for voice communications, crew productivity, alarm audibility, and restful sleep, and to minimize the risk for temporary and permanent hearing loss. Acoustic monitoring is an important part of the noise control process on ISS, providing critical data for trend analysis, noise exposure analysis, validation of acoustic analyses and predictions, and to provide strong evidence for ensuring crew health and safety, thus allowing Flight Certification. To this purpose, sound level meter (SLM) measurements and acoustic noise dosimetry are routinely performed. And since the primary noise sources on ISS include the environmental control and life support system (fans and airflow) and active thermal control system (pumps and water flow), acoustic monitoring will reveal changes in hardware noise emissions that may indicate system degradation or performance issues. This paper provides the current acoustic levels in the ISS modules and sleep stations and is an update to the status presented in 2011. Since this last status report, many payloads (science experiment hardware) have been added and a significant number of quiet ventilation fans have replaced noisier fans in the Russian Segment. Also, noise mitigation efforts are planned to reduce the noise levels of the T2 treadmill and levels in Node 3, in general. As a result, the acoustic levels on the ISS continue to improve.