WorldWideScience

Sample records for acoustic dispensing technology

  1. Methods and systems for integrating fluid dispensing technology with stereolithography

    Energy Technology Data Exchange (ETDEWEB)

    Medina, Francisco (El Paso, TX); Wicker, Ryan (El Paso, TX); Palmer, Jeremy A. (Albuquerque, NM); Davis, Don W. (Albuquerque, NM); Chavez, Bart D. (Albuquerque, NM); Gallegos, Phillip L. (Albuquerque, NM)

    2010-02-09

    An integrated system and method of integrating fluid dispensing technologies (e.g., direct-write (DW)) with rapid prototyping (RP) technologies (e.g., stereolithography (SL)) without part registration comprising: an SL apparatus and a fluid dispensing apparatus further comprising a translation mechanism adapted to translate the fluid dispensing apparatus along the Z-, Y- and Z-axes. The fluid dispensing apparatus comprises: a pressurized fluid container; a valve mechanism adapted to control the flow of fluid from the pressurized fluid container; and a dispensing nozzle adapted to deposit the fluid in a desired location. To aid in calibration, the integrated system includes a laser sensor and a mechanical switch. The method further comprises building a second part layer on top of the fluid deposits and optionally accommodating multi-layered circuitry by incorporating a connector trace. Thus, the present invention is capable of efficiently building single and multi-material SL fabricated parts embedded with complex three-dimensional circuitry using DW.

  2. Effect of holed reflector on acoustic radiation force in noncontact ultrasonic dispensing of small droplets

    Science.gov (United States)

    Tanaka, Hiroki; Wada, Yuji; Mizuno, Yosuke; Nakamura, Kentaro

    2016-06-01

    We investigated the fundamental aspects of droplet dispensing, which is an important procedure in the noncontact ultrasonic manipulation of droplets in air. A holed reflector was used to dispense a droplet from a 27.4 kHz standing-wave acoustic field to a well. First, the relationship between the hole diameter of the reflector and the acoustic radiation force acting on a levitated droplet was clarified by calculating the acoustic impedance of the point just above the hole. When the hole diameter was half of (or equal to) the acoustic wavelength λ, the acoustic radiation force was ∼80% (or 50%) of that without a hole. The maximal diameters of droplets levitated above the holes through flat and half-cylindrical reflectors were then experimentally investigated. For instance, with the half-cylindrical reflector, the maximal diameter was 5.0 mm for a hole diameter of 6.0 mm, and droplets were levitatable up to a hole diameter of 12 mm (∼λ).

  3. Unlocking the Potential of High-Throughput Drug Combination Assays Using Acoustic Dispensing.

    Science.gov (United States)

    Chan, Grace Ka Yan; Wilson, Stacy; Schmidt, Stephen; Moffat, John G

    2016-02-01

    Assessment of synergistic effects of drug combinations in vitro is a critical part of anticancer drug research. However, the complexities of dosing and analyzing two drugs over the appropriate range of doses have generally led to compromises in experimental design that restrict the quality and robustness of the data. In particular, the use of a single dose response of combined drugs, rather than a full two-way matrix of varying doses, has predominated in higher-throughput studies. Acoustic dispensing unlocks the potential of high-throughput dose matrix analysis. We have developed acoustic dispensing protocols that enable compound synergy assays in a 384-well format. This experimental design is considerably more efficient and flexible with respect to time, reagent usage, and labware than is achievable using traditional serial-dilution approaches. Data analysis tools integrated in Genedata Screener were used to efficiently deconvolute the combination compound mapping scheme and calculate compound potency and synergy metrics. We have applied this workflow to evaluate interactions among drugs targeting different nodes of the mitogen-activated protein kinase pathway in a panel of cancer cell lines. PMID:26160862

  4. Implementation and development of an automated, ultra-high-capacity, acoustic, flexible dispensing platform for assay-ready plate delivery.

    Science.gov (United States)

    Griffith, Dylan; Northwood, Roger; Owen, Paul; Simkiss, Ellen; Brierley, Andrew; Cross, Kevin; Slaney, Andrew; Davis, Miranda; Bath, Colin

    2012-10-01

    Compound management faces the daily challenge of providing high-quality samples to drug discovery. The advent of new screening technologies has seen demand for liquid samples move toward nanoliter ranges, dispensed by contactless acoustic droplet ejection. Within AstraZeneca, a totally integrated assay-ready plate production platform has been created to fully exploit the advantages of this technology. This enables compound management to efficiently deliver large throughputs demanded by high-throughput screening while maintaining regular delivery of smaller numbers of compounds in varying plate formats for cellular or biochemical concentration-response curves in support of hit and lead optimization (structure-activity relationship screening). The automation solution, CODA, has the capability to deliver compounds on demand for single- and multiple-concentration ranges, in batch sizes ranging from 1 sample to 2 million samples, integrating seamlessly into local compound and test management systems. The software handles compound orders intelligently, grouping test requests together dependent on output plate type and serial dilution ranges so that source compound vessels are shared among numerous tests, ensuring conservation of sample, reduced labware and costs, and efficiency of work cell logistics. We describe the development of CODA to address the customer demand, challenges experienced, learning made, and subsequent enhancements. PMID:22922543

  5. Polymer dispensing and embossing technology for the lens type LED packaging

    International Nuclear Information System (INIS)

    This study presents a ring-type micro-structure design on the substrate and its corresponding micro fabrication processes for a lens-type light-emitting diode (LED) package. The dome-type or crater-type silicone lenses are achieved by a dispensing and embossing process rather than a molding process. Silicone with a high viscosity and thixotropy index is used as the encapsulant material. The ring-type micro structure is adopted to confine the dispensed silicone encapsulant so as to form the packaged lens. With the architecture and process described, this LED package technology herein has three merits: (1) the flexibility of lens-type LED package designs is enhanced; (2) a dome-type package design is used to enhance the intensity; (3) a crater-type package design is used to enhance the view angle. Measurement results show the ratio between the lens height and lens radius can vary from 0.4 to 1 by changing the volume of dispensed silicone. The view angles of dome-type and crater-type packages can reach 155° ± 5° and 175° ± 5°, respectively. As compared with the commercial plastic leaded chip carrier-type package, the luminous flux of a monochromatic blue light LED is improved by 15% by the dome-type package (improved by 7% by the crater-type package) and the luminous flux of a white light LED is improved by 25% by the dome-type package (improved by 13% by the crater-type package). The luminous flux of monochromatic blue light LED and white light LED are respectively improved by 8% and 12% by the dome-type package as compare with the crater-type package. (paper)

  6. The convergence of systemic threads shaping a future South African healthcare dispensation: A technology management perspective

    Directory of Open Access Journals (Sweden)

    Richard Weeks

    2013-02-01

    Full Text Available Orientation: Underpinning healthcare service delivery are a number of support systems. This paper focuses on the development of a healthcare services framework that reflects the systems that need to be integrated, from a technology healthcare support perspective.Research purpose: The purpose of this paper is gain an understanding of some of the intricacies associated with the management of the transition to a future South African healthcare dispensation, with reference to the convergence of technology, financial healthcare and socio-political systems.Motivation for the study: South Africa is in the process of implementing the National Health Insurance initiative and the approach adopted will have a significant impact on the business model design.Research design, approach and method: A multidisciplinary literature study was undertaken. In addition, a limited narrative enquiry was also conducted. Practitioners interviewed were from the healthcare, informatics and management and technology sectors respectively. The research study constituted an insight study – analytically descriptive and not statistical in nature.Main findings: The literature reflects two very contrasting and different business models of healthcare service provision, namely a primarily curative and preventative stance. Each assumes a very different convergence of technology, healthcare, financial and social systems and consequently gives rise to contrasting business models. The dominant model appears to be based on primary healthcare, with a different technology support infrastructure to the previously-adopted curative approach. It is a model that would also appear to necessitate a complex adaptive management approach, necessitating a bottom-up as opposed to a top-down hierarchal management orientation.Contribution/Value-add: The National Healthcare Insurance initiative entails a very fundamental restructuring of the healthcare infrastructure. The insights gained from this

  7. Advanced Technology MEMS-based Acoustic Array Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Interdisciplinary Consulting Corporation proposes a technological advancement of current state-of-the-art acoustic energy harvester for harsh environment...

  8. Design, microfabrication, and characterization of a moulded PDMS/SU-8 inkjet dispenser for a Lab-on-a-Printer platform technology with disposable microfluidic chip.

    Science.gov (United States)

    Bsoul, Anas; Pan, Sheng; Cretu, Edmond; Stoeber, Boris; Walus, Konrad

    2016-08-16

    In this paper, we present a disposable inkjet dispenser platform technology and demonstrate the Lab-on-a-Printer concept, an extension of the ubiquitous Lab-on-a-Chip concept, whereby microfluidic modules are directly integrated into the printhead. The concept is demonstrated here through the integration of an inkjet dispenser and a microfluidic mixer enabling control over droplet composition from a single nozzle in real-time during printing. The inkjet dispenser is based on a modular design platform that enables the low-cost microfluidic component and the more expensive actuation unit to be easily separated, allowing for the optional disposal of the former and reuse of the latter. To limit satellite droplet formation, a hydrophobic-coated and tapered micronozzle was microfabricated and integrated with the fluidics to realize the dispenser. The microfabricated devices generated droplets with diameters ranging from 150-220 μm, depending mainly on the orifice diameter, with printing rates up to 8000 droplets per second. The inkjet dispenser is capable of dispensing materials with a viscosity up to ∼19 mPa s. As a demonstration of the inkjet dispenser function and application, we have printed type I collagen seeded with human liver carcinoma cells (cell line HepG2), to form patterned biological structures. PMID:27444216

  9. Design, microfabrication, and characterization of a moulded PDMS/SU-8 inkjet dispenser for a Lab-on-a-Printer platform technology with disposable microfluidic chip.

    Science.gov (United States)

    Bsoul, Anas; Pan, Sheng; Cretu, Edmond; Stoeber, Boris; Walus, Konrad

    2016-08-16

    In this paper, we present a disposable inkjet dispenser platform technology and demonstrate the Lab-on-a-Printer concept, an extension of the ubiquitous Lab-on-a-Chip concept, whereby microfluidic modules are directly integrated into the printhead. The concept is demonstrated here through the integration of an inkjet dispenser and a microfluidic mixer enabling control over droplet composition from a single nozzle in real-time during printing. The inkjet dispenser is based on a modular design platform that enables the low-cost microfluidic component and the more expensive actuation unit to be easily separated, allowing for the optional disposal of the former and reuse of the latter. To limit satellite droplet formation, a hydrophobic-coated and tapered micronozzle was microfabricated and integrated with the fluidics to realize the dispenser. The microfabricated devices generated droplets with diameters ranging from 150-220 μm, depending mainly on the orifice diameter, with printing rates up to 8000 droplets per second. The inkjet dispenser is capable of dispensing materials with a viscosity up to ∼19 mPa s. As a demonstration of the inkjet dispenser function and application, we have printed type I collagen seeded with human liver carcinoma cells (cell line HepG2), to form patterned biological structures.

  10. Microfluidic EmbryoSort technology: towards in flow analysis, sorting and dispensing of individual vertebrate embryos

    Science.gov (United States)

    Fuad, Nurul M.; Wlodkowic, Donald

    2013-12-01

    The demand to reduce the numbers of laboratory animals has facilitated the emergence of surrogate models such as tests performed on zebrafish (Danio rerio) or African clawed frog's (Xenopus levis) eggs, embryos and larvae. Those two model organisms are becoming increasingly popular replacements to current adult animal testing in toxicology, ecotoxicology and also in drug discovery. Zebrafish eggs and embryos are particularly attractive for toxicological analysis due their size (diameter 1.6 mm), optical transparency, large numbers generated per fish and very straightforward husbandry. The current bottleneck in using zebrafish embryos for screening purposes is, however, a tedious manual evaluation to confirm the fertilization status and subsequent dispensing of single developing embryos to multitier plates to perform toxicity analysis. Manual procedures associated with sorting hundreds of embryos are very monotonous and as such prone to significant analytical errors due to operator's fatigue. In this work, we present a proofof- concept design of a continuous flow embryo sorter capable of analyzing, sorting and dispensing objects ranging in size from 1.5 - 2.5 mm. The prototypes were fabricated in polymethyl methacrylate (PMMA) transparent thermoplastic using infrared laser micromachining. The application of additive manufacturing processes to prototype Lab-on-a-Chip sorters using both fused deposition manufacturing (FDM) and stereolithography (SLA) were also explored. The operation of the device was based on a revolving receptacle capable of receiving, holding and positioning single fish embryos for both interrogation and subsequent sorting. The actuation of the revolving receptacle was performed using a DC motor and/or microservo motor. The system was designed to separate between fertilized (LIVE) and non-fertilized (DEAD) eggs, based on optical transparency using infrared (IR) emitters and receivers.

  11. Dispensing nano-pico droplets of ferrofluids

    Science.gov (United States)

    Irajizad, Peyman; Farokhnia, Nazanin; Ghasemi, Hadi

    2015-11-01

    Dispensing miniature volumes of a ferrofluid is of fundamental and practical importance for diverse applications ranging from biomedical devices, optics, and self-assembly of materials. Current dispensing systems are based on microfluidics flow-focusing approaches or acoustic actuation requiring complicated structures. A simple method is presented to continuously dispense the miniature droplets from a ferrofluid reservoir. Once a jet of the ferrofluid is subjected to a constrained flux through a membrane and an inhomogeneous magnetic field, the jet experiences a curvature-driven instability and transforms to a droplet. Ferrofluid droplets in the range of 0.1-1000 nl are dispensed with tunable dispensing frequencies. A model is developed that predicts the dispensed volume of the ferrofluid droplets with an excellent agreement with the measurements.

  12. Micromachined chemical jet dispenser

    Energy Technology Data Exchange (ETDEWEB)

    Swierkowski, S.; Ciarlo, D.

    1996-05-13

    Goal is to develop a multi-channel micromachined chemical fluid jet dispenser that is applicable to prototype tests with biological samples that demonstrate its utility for molecular biology experiments. Objective is to demonstrate a new device capable of ultrasonically ejecting droplets from 10-200 {mu}m diameter capillaries that are arranged in an array that is linear or focused. The device is based on several common fabrication procedures used in MEMS (micro electro mechanical systems) technology: piezoelectric actuators, silicon, etc.

  13. Nanoprobe NAPPA Arrays for the Nanoconductimetric Analysis of Ultra-Low-Volume Protein Samples Using Piezoelectric Liquid Dispensing Technology

    Directory of Open Access Journals (Sweden)

    Eugenia Pechkova

    2015-03-01

    Full Text Available In the last years, the evolution and the advances of the nanobiotechnologies applied to the systematic study of proteins, namely proteomics, both structural and functional, and specifically the development of more sophisticated and largescale protein arrays, have enabled scientists to investigate protein interactions and functions with an unforeseeable precision and wealth of details. Here, we present a further advancement of our previously introduced and described Nucleic Acid Programmable Protein Arrays (NAPPA-based nanoconductometric sensor. We coupled Quartz Crystal Microbalance with Dissipation factor Monitoring (QCM_D with piezoelectric inkjet printing technology (namely, the newly developed ActivePipette, which enables to significantly reduce the volume of probe required for genes/proteins arrays. We performed a negative control (with master mix, or MM and a positive control (MM_p53 plus MDM2. We performed this experiment both in static and in flow, computing the apparent dissociation constant of p53-MDM2 complex (130 nM, in excellent agreement with the published literature. We compared the results obtained with the ActivePipette printing and dispensing technology vs. pin spotting. Without the ActivePipette, after MDM2 addition the shift in frequency (Δf was 7575 Hz and the corresponding adsorbed mass was 32.9 μg. With the ActivePipette technology, after MDM2 addition Δf was 7740 Hz and the corresponding adsorbed mass was 33.6 μg. With this experiment, we confirmed the sensing potential of our device, being able to discriminate each gene and protein as well as their interactions, showing for each one of them a unique conductance curve. Moreover, we obtained a better yield with the ActivePipette technology.

  14. Advanced Medication Dispenser

    Directory of Open Access Journals (Sweden)

    A.I. Alexan

    2013-12-01

    Full Text Available Medication dispensing is an important activity that can have major implications if done improperly. Dispensing must be done in the correct time interval, at the correct user, with the correct drug and dose. We propose a smart medication dispenser that can satisfy these needs and provide a mechanism for supervision. In order to ensure that the dispensing process is error free, the concept of a new smart medication container is used. A smart medication container is “smart” as it holds the medication dispensing parameters for the drugs it contains: dispensing time and date and name. Based on this information, the actual dispensing is done.

  15. Acoustic charge transport technology investigation for advanced development transponder

    Science.gov (United States)

    Kayalar, S.

    1993-01-01

    Acoustic charge transport (ACT) technology has provided a basis for a new family of analog signal processors, including a programmable transversal filter (PTF). Through monolithic integration of ACT delay lines with GaAs metal semiconductor field effect transistor (MESFET) digital memory and controllers, these devices significantly extend the performance of PTF's. This article introduces the basic operation of these devices and summarizes their present and future specifications. The production and testing of these devices indicate that this new technology is a promising one for future space applications.

  16. Development of Adaptive Acoustic Impedance Control Technologies of Acoustic Duct Liner

    Directory of Open Access Journals (Sweden)

    Hiroshi Kobayashi

    2011-01-01

    Full Text Available This paper describes the development of adaptive acoustic impedance control (AAC technologies to achieve a larger fan noise reduction, by adaptively adjusting reactance and resistance of the acoustic liner impedance. For the actual proof of the AAC technology III performance, the advanced fan noise absorption control duct liner II was made on trial basis, with the simple control system and the plain device. And, then, the duct liner II was examined for the AAC technology I, II, and III models, using the high speed fan test facility. The test results made clear that the duct liner II of the AAC technology III model could achieve the fan noise reduction higher than O.A. SPL 10 dB (A at the maximum fan speed 6000 rpm, containing the reduction of fundamental BPF tone of 18 dB and 2nd BPF tone of 10 dB in response to the fan peed change from 3000 to 6000 rpm.

  17. Advanced Medication Dispenser

    OpenAIRE

    A. I. Alexan; A. R. Osan; Oniga, S.

    2013-01-01

    Medication dispensing is an important activity that can have major implications if done improperly. Dispensing must be done in the correct time interval, at the correct user, with the correct drug and dose. We propose a smart medication dispenser that can satisfy these needs and provide a mechanism for supervision. In order to ensure that the dispensing process is error free, the concept of a new smart medication container is used. A smart medication container is “smart” ...

  18. Transport composite fuselage technology: Impact dynamics and acoustic transmission

    Science.gov (United States)

    Jackson, A. C.; Balena, F. J.; Labarge, W. L.; Pei, G.; Pitman, W. A.; Wittlin, G.

    1986-01-01

    A program was performed to develop and demonstrate the impact dynamics and acoustic transmission technology for a composite fuselage which meets the design requirements of a 1990 large transport aircraft without substantial weight and cost penalties. The program developed the analytical methodology for the prediction of acoustic transmission behavior of advanced composite stiffened shell structures. The methodology predicted that the interior noise level in a composite fuselage due to turbulent boundary layer will be less than in a comparable aluminum fuselage. The verification of these analyses will be performed by NASA Langley Research Center using a composite fuselage shell fabricated by filament winding. The program also developed analytical methodology for the prediction of the impact dynamics behavior of lower fuselage structure constructed with composite materials. Development tests were performed to demonstrate that the composite structure designed to the same operating load requirement can have at least the same energy absorption capability as aluminum structure.

  19. Tutorial on the Psychophysics and Technology of Virtual Acoustic Displays

    Science.gov (United States)

    Wenzel, Elizabeth M.; Null, Cynthia (Technical Monitor)

    1998-01-01

    Virtual acoustics, also known as 3-D sound and auralization, is the simulation of the complex acoustic field experienced by a listener within an environment. Going beyond the simple intensity panning of normal stereo techniques, the goal is to process sounds so that they appear to come from particular locations in three-dimensional space. Although loudspeaker systems are being developed, most of the recent work focuses on using headphones for playback and is the outgrowth of earlier analog techniques. For example, in binaural recording, the sound of an orchestra playing classical music is recorded through small mics in the two "ear canals" of an anthropomorphic artificial or "dummy" head placed in the audience of a concert hall. When the recorded piece is played back over headphones, the listener passively experiences the illusion of hearing the violins on the left and the cellos on the right, along with all the associated echoes, resonances, and ambience of the original environment. Current techniques use digital signal processing to synthesize the acoustical properties that people use to localize a sound source in space. Thus, they provide the flexibility of a kind of digital dummy head, allowing a more active experience in which a listener can both design and move around or interact with a simulated acoustic environment in real time. Such simulations are being developed for a variety of application areas including architectural acoustics, advanced human-computer interfaces, telepresence and virtual reality, navigation aids for the visually-impaired, and as a test bed for psychoacoustical investigations of complex spatial cues. The tutorial will review the basic psychoacoustical cues that determine human sound localization and the techniques used to measure these cues as Head-Related Transfer Functions (HRTFs) for the purpose of synthesizing virtual acoustic environments. The only conclusive test of the adequacy of such simulations is an operational one in which

  20. Theoretical detection ranges for acoustic based manatee avoidance technology.

    Science.gov (United States)

    Phillips, Richard; Niezrecki, Christopher; Beusse, Diedrich O

    2006-07-01

    The West Indian manatee (Trichechus manatus latirostris) has become endangered partly because of watercraft collisions in Florida's coastal waterways. To reduce the number of collisions, warning systems based upon detecting manatee vocalizations have been proposed. One aspect of the feasibility of an acoustically based warning system relies upon the distance at which a manatee vocalization is detectable. Assuming a mixed spreading model, this paper presents a theoretical analysis of the system detection capabilities operating within various background and watercraft noise conditions. This study combines measured source levels of manatee vocalizations with the modeled acoustic properties of manatee habitats to develop a method for determining the detection range and hydrophone spacing requirements for acoustic based manatee avoidance technologies. In quiet environments (background noise approximately 70 dB) it was estimated that manatee vocalizations are detectable at approximately 250 m, with a 6 dB detection threshold, In louder environments (background noise approximately 100dB) the detection range drops to 2.5 m. In a habitat with 90 dB of background noise, a passing boat with a maximum noise floor of 120 dB would be the limiting factor when it is within approximately 100 m of a hydrophone. The detection range was also found to be strongly dependent on the manatee vocalization source level. PMID:16875213

  1. Structural Acoustic Prediction and Interior Noise Control Technology

    Science.gov (United States)

    Mathur, G. P.; Chin, C. L.; Simpson, M. A.; Lee, J. T.; Palumbo, Daniel L. (Technical Monitor)

    2001-01-01

    This report documents the results of Task 14, "Structural Acoustic Prediction and Interior Noise Control Technology". The task was to evaluate the performance of tuned foam elements (termed Smart Foam) both analytically and experimentally. Results taken from a three-dimensional finite element model of an active, tuned foam element are presented. Measurements of sound absorption and sound transmission loss were taken using the model. These results agree well with published data. Experimental performance data were taken in Boeing's Interior Noise Test Facility where 12 smart foam elements were applied to a 757 sidewall. Several configurations were tested. Noise reductions of 5-10 dB were achieved over the 200-800 Hz bandwidth of the controller. Accelerometers mounted on the panel provided a good reference for the controller. Configurations with far-field error microphones outperformed near-field cases.

  2. A Change in Dispensing Technology --Jetting Takes off%非接触式喷射点胶--未来的点胶技术

    Institute of Scientific and Technical Information of China (English)

    Steven J. Adamson; David Wang

    2004-01-01

    Jetting of epoxies and other materials is going to change the way people do dispensing. For the last twenty years, dispensing has evolved from merely pushing fluid through a needle to a highly automated production process. Controlling fluid deposition, needle positioning and dispensed volume accuracy has dramatically improved in recent years. Additionally, speed has increased while software has simplified operational control. Now jet dispensing fluids has become practical and it is going to have as large an impact on the electronics assembly industry that Ink Jet printing has had in the office / home environment.

  3. Safety and Traceability in Patient Healthcare through the Integration of RFID Technology for Intravenous Mixtures in the Prescription-Validation-Elaboration-Dispensation-Administration Circuit to Day Hospital Patients

    Science.gov (United States)

    Martínez Pérez, María; Vázquez González, Guillermo; Dafonte, Carlos

    2016-01-01

    This work presents the integration of the RFID technology with the aim of ensuring the traceability of patients and minimization of adverse events during the process of prescription-validation-elaboration-dispensation-administration of medication by means of the implementation of various passive and active WIFI RFID systems in the Pharmacy and Day Hospital services of the Complejo Hospitalario Universitario A Coruña. Obtaining patient traceability and using the patient/drug binomial during this process allows us to minimize the occurrence of adverse events. The key points in this work are the unmistakably unique identification and accurate real time location of the controlled items (patients and medication). RFID technology has proved to be invaluable in assisting with the everyday clinical practice of a hospital, and has been successfully implemented in this environment and others. In services such as the day hospital, the implementation of said technology is further justified by the high costs of the service and the high risk to the patient. PMID:27483269

  4. Safety and Traceability in Patient Healthcare through the Integration of RFID Technology for Intravenous Mixtures in the Prescription-Validation-Elaboration-Dispensation-Administration Circuit to Day Hospital Patients.

    Science.gov (United States)

    Martínez Pérez, María; Vázquez González, Guillermo; Dafonte, Carlos

    2016-01-01

    This work presents the integration of the RFID technology with the aim of ensuring the traceability of patients and minimization of adverse events during the process of prescription-validation-elaboration-dispensation-administration of medication by means of the implementation of various passive and active WIFI RFID systems in the Pharmacy and Day Hospital services of the Complejo Hospitalario Universitario A Coruña. Obtaining patient traceability and using the patient/drug binomial during this process allows us to minimize the occurrence of adverse events. The key points in this work are the unmistakably unique identification and accurate real time location of the controlled items (patients and medication). RFID technology has proved to be invaluable in assisting with the everyday clinical practice of a hospital, and has been successfully implemented in this environment and others. In services such as the day hospital, the implementation of said technology is further justified by the high costs of the service and the high risk to the patient.

  5. Safety and Traceability in Patient Healthcare through the Integration of RFID Technology for Intravenous Mixtures in the Prescription-Validation-Elaboration-Dispensation-Administration Circuit to Day Hospital Patients

    Directory of Open Access Journals (Sweden)

    María Martínez Pérez

    2016-07-01

    Full Text Available This work presents the integration of the RFID technology with the aim of ensuring the traceability of patients and minimization of adverse events during the process of prescription-validation-elaboration-dispensation-administration of medication by means of the implementation of various passive and active WIFI RFID systems in the Pharmacy and Day Hospital services of the Complejo Hospitalario Universitario A Coruña. Obtaining patient traceability and using the patient/drug binomial during this process allows us to minimize the occurrence of adverse events. The key points in this work are the unmistakably unique identification and accurate real time location of the controlled items (patients and medication. RFID technology has proved to be invaluable in assisting with the everyday clinical practice of a hospital, and has been successfully implemented in this environment and others. In services such as the day hospital, the implementation of said technology is further justified by the high costs of the service and the high risk to the patient.

  6. Safety and Traceability in Patient Healthcare through the Integration of RFID Technology for Intravenous Mixtures in the Prescription-Validation-Elaboration-Dispensation-Administration Circuit to Day Hospital Patients.

    Science.gov (United States)

    Martínez Pérez, María; Vázquez González, Guillermo; Dafonte, Carlos

    2016-01-01

    This work presents the integration of the RFID technology with the aim of ensuring the traceability of patients and minimization of adverse events during the process of prescription-validation-elaboration-dispensation-administration of medication by means of the implementation of various passive and active WIFI RFID systems in the Pharmacy and Day Hospital services of the Complejo Hospitalario Universitario A Coruña. Obtaining patient traceability and using the patient/drug binomial during this process allows us to minimize the occurrence of adverse events. The key points in this work are the unmistakably unique identification and accurate real time location of the controlled items (patients and medication). RFID technology has proved to be invaluable in assisting with the everyday clinical practice of a hospital, and has been successfully implemented in this environment and others. In services such as the day hospital, the implementation of said technology is further justified by the high costs of the service and the high risk to the patient. PMID:27483269

  7. Light-induced immobilisation of biomolecules as an attractive alternative to microdroplet dispensing-based arraying technologies

    DEFF Research Database (Denmark)

    Crookshanks, Meg; Skovsen, Esben; Petersen, Maria Teresa Neves;

    2007-01-01

    of reproducibility. This technology can be used to circumvent the need for often expensive nano/microdispensing technologies. The ultimate size of the immobilised spots is defined by the focal area of the UV beam, which for a diffraction-limited beam can be less than 1 mm in diameter. LIMI has the added benefit...... to conventional array formats. The ultimate consequence of the LIMI is that it is possible to write complex protein patterns using bitmaps at high resolution onto substrates. Thus, LIMI of biomolecules provides a new technological platform for biomolecular immobilisation and the potential for replacing present...

  8. Acoustic Energy: An Innovative Technology for Stimulating Oil Wells

    Energy Technology Data Exchange (ETDEWEB)

    Edgar, Dorland E.; Peters, Robert W.; Johnson, Donald O.; Paulsen, P. David; Roberts, Wayne

    2006-04-30

    application of acoustic energy (sonication) significantly reduced the viscosity of crude oils, and the amount of viscosity reduction resulting is greater for more viscous, heavy crude oils than it is for less viscous, light crude oils. (2) Test results showed that after being heated, resulting viscosity reductions were not sustained following treatment to the extent that post-sonication reductions were sustained. (3) The maximum viscosity reductions in Oils 1, 2, and 3 due to sonication were 43%, 76%, and 6%, respectively. Samples of Oil 2 associated with larger viscosity reductions often exhibited a definite water separation layer follow the tests, whereas reductions of approximately 23% were measured when this separation was not observed. (4) It was observed that neither horn design nor the reduction of input power by 25% had very little effect on the ability of sonication to alter crude oil viscosity. (5) The chemical additives produced a range of viscosity reduction from 37% to a maximum of 94% with the largest reductions being facilitated by the abundant water present Oil 2. If the Oil 2 results are not considered, the maximum reduction was 73%. The effects of the additives and sonication are enhanced by each other. (6) In only one test did the viscosity return to as much as 50% of the pre-treatment value during a period of 30 days following treatment; recovery was much less in all other cases. Therefore, more than half of the viscosity reduction was maintained for a month without additional treatment. (7) Possible applications, market potential, and economic value of the implementation of a mature sonication technology within the petroleum industry were identified, and it was estimated that the potential exists that more than a billion barrels of oil could be upgraded or produced annually as a result. The project results successfully demonstrated that sonication alone and in combination with chemical additives can effectively reduce the viscosity of crude oils having a

  9. A Simulated Learning Environment for Teaching Medicine Dispensing Skills

    Science.gov (United States)

    Styles, Kim; Sewell, Keith; Trinder, Peta; Marriott, Jennifer; Maher, Sheryl; Naidu, Som

    2016-01-01

    Objective. To develop an authentic simulation of the professional practice dispensary context for students to develop their dispensing skills in a risk-free environment. Design. A development team used an Agile software development method to create MyDispense, a web-based simulation. Modeled on virtual learning environments elements, the software employed widely available standards-based technologies to create a virtual community pharmacy environment. Assessment. First-year pharmacy students who used the software in their tutorials, were, at the end of the second semester, surveyed on their prior dispensing experience and their perceptions of MyDispense as a tool to learn dispensing skills. Conclusion. The dispensary simulation is an effective tool for helping students develop dispensing competency and knowledge in a safe environment. PMID:26941437

  10. Dispenser printed electroluminescent lamps on textiles for smart fabric applications

    Science.gov (United States)

    de Vos, Marc; Torah, Russel; Tudor, John

    2016-04-01

    Flexible electroluminescent (EL) lamps are fabricated onto woven textiles using a novel dispenser printing process. Dispenser printing utilizes pressurized air to deposit ink onto a substrate through a syringe and nozzle. This work demonstrates the first use of this technology to fabricate EL lamps. The luminance of the dispenser printed EL lamps is compared to screen-printed EL lamps, both printed on textile, and also commercial EL lamps on polyurethane film. The dispenser printed lamps are shown to have a 1.5 times higher luminance than the best performing commercially available lamp, and have a comparable performance to the screen-printed lamps.

  11. Physician drug dispensing.

    Science.gov (United States)

    Lober, C W; Behlmer, S D; Penneys, N S; Shupack, J L; Thiers, B H

    1988-11-01

    We have reviewed the issue of physician drug dispensing by focusing upon quality of care, economic considerations, drug availability, patient compliance, safety, and increased governmental regulation. From a quality of care perspective, the increased use of pharmacist assistants, the tendency toward generic and therapeutic drug substitution, and the less specialized clinical education of pharmacists all pose hazards rather than safety checks upon physician prescribing. There is no evidence that pharmacists charge less than physicians. If they did, there would be no need to protect their incomes legislatively by restricting physician dispensing. Economic motivation per se is less important to a physician than providing a true convenience for his patients and thus encouraging a closer doctor-patient relationship. Physician dispensing adds to the availability of medication and may minimize the number of patients shuttling between pharmacies to obtain complex multi-ingredient preparations. Compliance is enhanced as availability increases. Prepackaged pharmaceuticals prepared under the auspices of pharmacists and dispensed by physicians are at least as safe as those prepared by the ungloved hands of a pharmacist hidden behind store counters. Thus, restricting the physician's right to dispense can negatively affect the quality of medical care, the cost of medications, safety, the availability of pharmaceuticals, and patient compliance. Such limitation is certainly not in the best interest of our patients. PMID:3056999

  12. The last half-repeat of transcription activator-like effector (TALE) is dispensable and thereby TALE-based technology can be simplified.

    Science.gov (United States)

    Zheng, Chong-Ke; Wang, Chun-Lian; Zhang, Xiao-Ping; Wang, Fu-Jun; Qin, Teng-Fei; Zhao, Kai-Jun

    2014-09-01

    To activate the expression of host genes that contribute to pathogen growth, pathogenic Xanthomonas bacteria inject their transcription activator-like effectors (TALEs) into plant cells and the TALEs bind to target gene promoters by the central repeat region consisting of near-perfect 34-amino-acid repeats (34-aa repeats). Based on the recognition codes between the 34-aa repeats and the targeted nucleotides, TALE-based technologies, such as designer TALEs (dTALEs) and TALE nucleases (TALENs), have been developed. Amazingly, every natural TALE invariantly has a truncated last half-repeat (LHR) at the end of the 34-aa repeats. Consequently, all the reported dTALEs and TALENs also harbour their LHRs. Here, we show that the LHRs in dTALEs are dispensable for the function of gene activation by both transient expression assays in Nicotiana benthamiana and gene-specific targeting in the rice genome, indicating that TALEs might originate from a single progenitor. In the light of this finding, we demonstrate that dTALEs can be constructed through two simple steps. Moreover, the activation strengths of dTALEs lacking the LHR are comparable with those of dTALEs harbouring the LHR. Our results provide new insights into the origin of natural TALEs, and will facilitate the simplification of the design and assembly of TALE-based tools, such as dTALEs and TALENs, in the near future.

  13. The study of underwater acoustic communication technology based-on the acoustic vector sensor

    Institute of Scientific and Technical Information of China (English)

    QIAO Gang; SANG Enfang

    2007-01-01

    Underwater acoustic (UWA) communication based on an acoustic vector sensor is studied. The method of joint weighted sound pressure and velocity processing is used in phase modulation high-speed UWA communication system combined with coherent demodulation and adaptive equalization algorithm to demodulate and decode. Whereas the sound intensity could be used instead of pressure for frequency decoding in frequency modulation UWA communication system. The results of theory analysis, simulation calculations and lake trials have shown that either in phase modulation or in frequency modulation UWA communication system, the processing gain can be evidently increased, so that the BER (bit error rate) can be effectively reduced and the telemetry distance can be enlarged by using the acoustic vector sensor.

  14. Acoustic Energy: An Innovative Technology for Stimulating Oil Wells

    Energy Technology Data Exchange (ETDEWEB)

    Edgar, Dorland E.; Peters, Robert W.; Johnson, Donald O.; Paulsen, P. David; Roberts, Wayne

    2006-04-30

    application of acoustic energy (sonication) significantly reduced the viscosity of crude oils, and the amount of viscosity reduction resulting is greater for more viscous, heavy crude oils than it is for less viscous, light crude oils. (2) Test results showed that after being heated, resulting viscosity reductions were not sustained following treatment to the extent that post-sonication reductions were sustained. (3) The maximum viscosity reductions in Oils 1, 2, and 3 due to sonication were 43%, 76%, and 6%, respectively. Samples of Oil 2 associated with larger viscosity reductions often exhibited a definite water separation layer follow the tests, whereas reductions of approximately 23% were measured when this separation was not observed. (4) It was observed that neither horn design nor the reduction of input power by 25% had very little effect on the ability of sonication to alter crude oil viscosity. (5) The chemical additives produced a range of viscosity reduction from 37% to a maximum of 94% with the largest reductions being facilitated by the abundant water present Oil 2. If the Oil 2 results are not considered, the maximum reduction was 73%. The effects of the additives and sonication are enhanced by each other. (6) In only one test did the viscosity return to as much as 50% of the pre-treatment value during a period of 30 days following treatment; recovery was much less in all other cases. Therefore, more than half of the viscosity reduction was maintained for a month without additional treatment. (7) Possible applications, market potential, and economic value of the implementation of a mature sonication technology within the petroleum industry were identified, and it was estimated that the potential exists that more than a billion barrels of oil could be upgraded or produced annually as a result. The project results successfully demonstrated that sonication alone and in combination with chemical additives can effectively reduce the viscosity of crude oils having a

  15. Mississippi Curriculum Framework for Ophthalmic Technology (Program CIP: 51.1801--Opticianry/Dispensing Optician). Postsecondary Programs.

    Science.gov (United States)

    Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.

    This document, which is intended for use by community and junior colleges throughout Mississippi, contains curriculum frameworks for the course sequences in the ophthalmic technology program. Presented in the introductory section are a description of the program and suggested course sequence. Section I lists baseline competencies, and section II…

  16. Marine bioacoustics and technology: The new world of marine acoustic ecology

    Science.gov (United States)

    Hastings, Mardi C.; Au, Whitlow W. L.

    2012-11-01

    Marine animals use sound for communication, navigation, predator avoidance, and prey detection. Thus the rise in acoustic energy associated with increasing human activity in the ocean has potential to impact the lives of marine animals. Thirty years ago marine bioacoustics primarily focused on evaluating effects of human-generated sound on hearing and behavior by testing captive animals and visually observing wild animals. Since that time rapidly changing electronic and computing technologies have yielded three tools that revolutionized how bioacousticians study marine animals. These tools are (1) portable systems for measuring electrophysiological auditory evoked potentials, (2) miniaturized tags equipped with positioning sensors and acoustic recording devices for continuous short-term acoustical observation rather than intermittent visual observation, and (3) passive acoustic monitoring (PAM) systems for remote long-term acoustic observations at specific locations. The beauty of these breakthroughs is their direct applicability to wild animals in natural habitats rather than only to animals held in captivity. Hearing capabilities of many wild species including polar bears, beaked whales, and reef fishes have now been assessed by measuring their auditory evoked potentials. Miniaturized acoustic tags temporarily attached to an animal to record its movements and acoustic environment have revealed the acoustic foraging behavior of sperm and beaked whales. Now tags are being adapted to fishes in effort to understand their behavior in the presence of noise. Moving and static PAM systems automatically detect and characterize biological and physical features of an ocean area without adding any acoustic energy to the environment. PAM is becoming a powerful technique for understanding and managing marine habitats. This paper will review the influence of these transformative tools on the knowledge base of marine bioacoustics and elucidation of relationships between marine

  17. Communication Acoustics

    DEFF Research Database (Denmark)

    Blauert, Jens

    Communication Acoustics deals with the fundamentals of those areas of acoustics which are related to modern communication technologies. Due to the advent of digital signal processing and recording in acoustics, these areas have enjoyed an enormous upswing during the last 4 decades. The book...... the book a source of valuable information for those who want to improve or refresh their knowledge in the field of communication acoustics - and to work their way deeper into it. Due to its interdisciplinary character Communication Acoustics is bound to attract readers from many different areas, such as......: acoustics, cognitive science, speech science, and communication technology....

  18. Holy grail: Pioneering acoustic telemetry technology set to revolutionize downhole communication

    Energy Technology Data Exchange (ETDEWEB)

    Greenaway, R.

    2003-12-01

    Acoustic telemetry, a faster and more efficient downhole-to-surface-communication technology, is the latest development in downhole communication systems. The system has been developed by Extreme Engineering Limited of Calgary, led by Derek Logan, founder and one-time senior vice-president of Ryan Energy Technologies that developed the original measurement -while-drilling (MWD) and logging-while-drilling )LWD) tools. The company predicts that acoustic telemetry will cause a massive transformation of the drilling industry in Western Canada once the technology is commercialized. Conventional MWD techniques, based on mud-pulse technology, have been industry standard since the 1970s, but mud-pulse technology is now considered extremely slow. In the 1980s industry came up electromagnetic telemetry, as an alternative to mud-pulse. Today, the need to transmit ever more data, the need for a faster communications system and greater wellbore control, has become even more pressing. Logan believes that acoustic technology is the answer. It is not only capable of transmitting data 20 to 30 times faster than mud-pulse telemetries, it can also communicate massive amounts of data. It can be used in drilling, completion production, drillstem testing, frac monitoring and any other wellbore process requiring wireless real-time telemetry. Acoustic telemetry is also the only wireless system that can perform MWD and LWD in offshore underbalanced drilling. Notwithstanding its great promise, Extreme Engineering Limited had considerable difficulty raising funds for developing and commercializing XAcT (the trade name for acoustic telemetry). Prospects are reported to have been substantially improved by recent infusion of funds by the federal Industrial Research Assistance Program (IRAP) , and XAcT's recognition by R and D Magazine with one of the R and D 100 awards for 2003. 3 figs.

  19. E85 Dispenser Study

    Energy Technology Data Exchange (ETDEWEB)

    Moriarty, K.; Johnson, C.; Sears, T.; Bergeron, P.

    2009-12-01

    This study reviews E85 dispensing infrastructure advances and issues and evaluates the geographic concentration of flexible fuel vehicles (FFVs), E85 stations, ethanol production facilities, and E85 suppliers. Costs, space, financial incentives, and barriers to adding E85 fueling equipment at existing stations are also assessed. This study found that E85 is increasingly available in the U.S. in half of the states; however, the other half have minimal or no E85 fueling options. Despite these gains, E85 is only available at 1% of U.S. gasoline stations. Ethanol production reached 9.5 billion gallons in 2008, but less than 1% is consumed as E85. FFVs have not reached a significant concentration in any county, metropolitan area, or state.

  20. Submunition Dispensing Mechanisms .

    Directory of Open Access Journals (Sweden)

    S.L. Kholi

    1997-10-01

    Full Text Available The effectiveness of a weapon system is enhanced manifold when it is incorporated with submunitions instead of being a unitary one. A large unitary warhead produces effects that are too concentrated and localised for many target types, resulting in a very high probability of either causing no damage or an over-kill. The submunition warhead incorporating a single-stage ejection process has the drawbacks of lesser area coverage and non-uniform distribution of submunitions. To overcome the above drawbacks, dispensing mechanisms with multistage ejection of submunitions are being employed worldwide by the warhead designers. Extensive work has been carried out by the authors to achieve wide area coverage by using multistage ejection instead of single-stage ejection.

  1. Distributed Acoustic Sensing Technology in a Magmatic Geothermal Field - First Results From a Survey in Iceland

    Science.gov (United States)

    Reinsch, Thomas; Jousset, Philippe; Henninges, Jan; Blanck, Hanna

    2016-04-01

    Seismic methods are particularly suited for investigating the Earth's subsurface. Compared to surface-measurements , wellbore measurements can be used to acquire more detailed information about rock properties and possible fluid pathways within a geothermal reservoir. For high temperature geothermal wells, however, ambient temperatures are often far above the operating temperature range of conventional geophones. One way to overcome this limitation is the application of fiber optic sensor systems, where only the passive optical fiber is subjected to downhole conditions. Their applicability is thus determined by the operating temperature range of the optical fiber. Choosing appropriate fibers, such sensor systems can be operated at temperatures far above 200°C. Along an optical fiber, the distributed acoustic sensing technology (DAS) can be used to acquire acoustic signals with a high spatial and temporal resolution. Previous experiments have shown that the DAS technology is well suited for active seismic measurements. Within the framework of the EC funded project IMAGE, a fiber optic cable was deployed in a newly drilled geothermal well (RN-34) within the Reykjanes geothermal field, Iceland. Additionally, a >15 km fiber optic cable, already available at the surface, was connected to a DAS read-out unit. Acoustic data was acquired continuously for 9 days. Hammer shots were performed at the wellhead as well as along the surface cable in order to locate individual acoustic traces and calibrate the spatial distribution of the acoustic information. During the monitoring period both signals from on- and offshore explosive sources and natural seismic events could be recorded. We compare the fiber optic data to conventional seismic records from a dense seismic network deployed on the Reykjanes in the course of the IMAGE project. Here, first results from the seismic survey will be presented.

  2. Report of the working group on fisheries acoustics science and technology (WGFAST)

    OpenAIRE

    ICES

    2005-01-01

    The Working Group on Fisheries Acoustics Science and Technology (WGFAST) met at the Food and Agricultural Organisation of the United Nations in Rome, Italy, from 19–22 April 2005. David A. Demer, USA, was Chair, Alex De Robertis, USA, was Rapporteur and Jessica D. Lipsky, USA, was the Recorder. There were 83 participants from 16 countries. a ) The first topic was “Measuring underwater radiated noise from survey vessels and its effects on fish”. Quiet vessels have distinct advantages over c...

  3. Shaping acoustic fields as a toolset for microfluidic manipulations in diagnostic technologies.

    Science.gov (United States)

    Reboud, Julien; Bourquin, Yannyk; Wilson, Rab; Pall, Gurman S; Jiwaji, Meesbah; Pitt, Andrew R; Graham, Anne; Waters, Andrew P; Cooper, Jonathan M

    2012-09-18

    Ultrasonics offers the possibility of developing sophisticated fluid manipulation tools in lab-on-a-chip technologies. Here we demonstrate the ability to shape ultrasonic fields by using phononic lattices, patterned on a disposable chip, to carry out the complex sequence of fluidic manipulations required to detect the rodent malaria parasite Plasmodium berghei in blood. To illustrate the different tools that are available to us, we used acoustic fields to produce the required rotational vortices that mechanically lyse both the red blood cells and the parasitic cells present in a drop of blood. This procedure was followed by the amplification of parasitic genomic sequences using different acoustic fields and frequencies to heat the sample and perform a real-time PCR amplification. The system does not require the use of lytic reagents nor enrichment steps, making it suitable for further integration into lab-on-a-chip point-of-care devices. This acoustic sample preparation and PCR enables us to detect ca. 30 parasites in a microliter-sized blood sample, which is the same order of magnitude in sensitivity as lab-based PCR tests. Unlike other lab-on-a-chip methods, where the sample moves through channels, here we use our ability to shape the acoustic fields in a frequency-dependent manner to provide different analytical functions. The methods also provide a clear route toward the integration of PCR to detect pathogens in a single handheld system. PMID:22949692

  4. Development of Acoustic Emission Technology for Condition Monitoring and Diagnosis of Rotating Machines; Bearings, Pumps, Gearboxes, Engines and Rotating Structures.

    OpenAIRE

    Mba, David; Rao, Raj B. K. N.

    2006-01-01

    One of the earliest documented applications of Acoustic Emission Technology (AET) to rotating machinery monitoring was in the late 1960s. Since then there has been an explosion in research and application based studies covering bearings, pumps, gearboxes, engines and rotating structures. This paper presents a comprehensive and critical review to date on the application of Acoustic Emission Technology to condition monitoring and diagnostics of rotating machinery.

  5. Evaluation of a liquid dispenser for assay development and enzymology in 1536-well format.

    Science.gov (United States)

    Butendeich, Heike; Pierret, Noëlle M; Numao, Shin

    2013-06-01

    Although developments in liquid dispensers have made the use of 1536-well plates for high-throughput screening (HTS) standard, there is still a gap in dispenser technology for performing matrix experiments with several components. Experiments such as those performed during assay development and enzymological studies are therefore still performed by manual pipetting in lower-density plates. We have evaluated a new dispenser, the Certus liquid dispenser (Gyger Fluidics GmbH, Switzerland), that is capable of flexible dispensing in 1536-well format, with a dead volume of less than 200 µL. Taking advantage of the precision of the dispenser for volumes down to 50 nL, we have created concentration gradients on plates by dispensing different volumes of reagent and then backfilling with buffer. Using this method and the flexibility of the dispenser software, we have performed several multidimensional experiments varying two to three components, including an assay development for an HTS, a mode of inhibition study, and a cofactor optimization, in which we determined 32 KM values. Overall, the flexibility of the plate layout for multiple components, the accuracy to dispense volumes ranging 2 log orders, and minimal reagent usage enable this dispenser for complex biochemical experiments.

  6. Novel acoustic technology for studying free-ranging shark social behaviour by recording individuals' interactions.

    Directory of Open Access Journals (Sweden)

    Tristan L Guttridge

    Full Text Available Group behaviours are widespread among fish but comparatively little is known about the interactions between free-ranging individuals and how these might change across different spatio-temporal scales. This is largely due to the difficulty of observing wild fish groups directly underwater over long enough time periods to quantify group structure and individual associations. Here we describe the use of a novel technology, an animal-borne acoustic proximity receiver that records close-spatial associations between free-ranging fish by detection of acoustic signals emitted from transmitters on other individuals. Validation trials, held within enclosures in the natural environment, on juvenile lemon sharks Negaprion brevirostris fitted with external receivers and transmitters, showed receivers logged interactions between individuals regularly when sharks were within 4 m ( approximately 4 body lengths of each other, but rarely when at 10 m distance. A field trial lasting 17 days with 5 juvenile lemon sharks implanted with proximity receivers showed one receiver successfully recorded association data, demonstrating this shark associated with 9 other juvenile lemon sharks on 128 occasions. This study describes the use of acoustic underwater proximity receivers to quantify interactions among wild sharks, setting the scene for new advances in understanding the social behaviours of marine animals.

  7. Slow Release of Plant Volatiles Using Sol-Gel Dispensers.

    Science.gov (United States)

    Bian, L; Sun, X L; Cai, X M; Chen, Z M

    2014-12-01

    The black citrus aphid, also known as the tea aphid, (Toxoptera aurantii Boyer) attacks economically important crops, including tea (Camellia sinensis (L.) O. Kuntze). In the current study, silica sol-gel formulations were screened to find one that could carry and release C. sinensis plant volatiles to lure black citrus aphids in a greenhouse. The common plant volatile trans-2-hexen-1-al was used as a model molecule to screen for suitable sol-gel formulations. A zNose (Electronic Sensor Technology, Newbury Park, CA) transportable gas chromatograph was used to continuously monitor the volatile emissions. A sol-gel formulation containing tetramethyl orthosilicate and methyltrimethoxysilane in an 8:2 (vol:vol) ratio was selected to develop a slow-release dispenser. The half-life of trans-2-hexen-1-al in the sol-gel dispenser increased slightly with the volume of this compound in the dispenser. Ten different volatiles were tested in the sol-gel dispenser. Alcohols of 6-10 carbons had the longest half-lives (3.01-3.77 d), while esters of 6-12 carbons had the shortest (1.53-2.28 d). Release of these volatiles from the dispensers could not be detected by the zNose after 16 d (cis-3-hexenyl acetate) to 26 d (3,7-dimethylocta-1,6-dien-3-ol). In greenhouse experiments, trans-2-hexen-1-al and cis-3-hexen-1-ol released from the sol-gel dispensers attracted aphids for ≍17 d, and release of these volatiles could not be detected by the zNose after ≍24 d. The sol-gel dispensers performed adequately for the slow release of plant volatiles to trap aphids in the greenhouse. PMID:26470065

  8. Laser cleaning of steam generator tubing based on acoustic emission technology

    Energy Technology Data Exchange (ETDEWEB)

    Hou, Su-xia; Luo, Ji-jun; Shen, Tao; Li, Ru-song [Xi' an Hi-Tech Institute, Xi' an (China)

    2015-12-15

    As a physical method, laser cleaning technology in equipment maintenance will be a good prospect. The experimental apparatus for laser cleaning of heat tubes in the steam generator was designed according to the results of theoretical analysis. There are two conclusions; one is that laser cleaning technology is attached importance to traditional methods. Which has advantages in saving on much manpower and material resource and it is a good cleaning method for heat tubes. The other is that the acoustic emission signal includes lots of information on the laser cleaning process, which can be used as real-time monitoring in laser cleaning processes. When the laser acts for 350 s, 100 % contaminants of heat tubes is cleaned off, and the sensor only receives weak AE signal at that time.

  9. 21 CFR 888.4200 - Cement dispenser.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Cement dispenser. 888.4200 Section 888.4200 Food... DEVICES ORTHOPEDIC DEVICES Surgical Devices § 888.4200 Cement dispenser. (a) Identification. A cement dispenser is a nonpowered syringe-like device intended for use in placing bone cement (§ 888.3027)...

  10. Acoustical Imaging

    CERN Document Server

    Litniewski, Jerzy; Kujawska, Tamara; 31st International Symposium on Acoustical Imaging

    2012-01-01

    The International Symposium on Acoustical Imaging is a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. This interdisciplinary Symposium has been taking place continuously since 1968. In the course of the years the proceedings volumes in the Acoustical Imaging Series have become a reference for cutting-edge research in the field. In 2011 the 31st International Symposium on Acoustical Imaging was held in Warsaw, Poland, April 10-13. Offering both a broad perspective on the state-of-the-art as well as  in-depth research contributions by the specialists in the field, this Volume 31 in the Series contains an excellent collection of papers in six major categories: Biological and Medical Imaging Physics and Mathematics of Acoustical Imaging Acoustic Microscopy Transducers and Arrays Nondestructive Evaluation and Industrial Applications Underwater Imaging

  11. Dispensing of non-prescribed antibiotics in Jordan

    Directory of Open Access Journals (Sweden)

    Almaaytah A

    2015-09-01

    Full Text Available Ammar Almaaytah,1 Tareq L Mukattash,2 Julia Hajaj2 1Department of Pharmaceutical Technology, 2Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan Objective: Current regulations in Jordan state that antibiotics cannot be sold without a medical prescription. This study aimed to assess the percentage of pharmacies that dispense antibiotics without a medical prescription in the Kingdom of Jordan and identify and highlight the extent and seriousness of such practices among Jordanian pharmacies. Methods: A prospective study was performed, and five different clinical scenarios were simulated at pharmacies investigated including sore throat, otitis media, acute sinusitis, diarrhea, and urinary tract infection in childbearing-aged women. Three levels of demand were used to convince the pharmacists to sell an antibiotic. Results: A total of 202 total pharmacies in Jordan were visited in the present study. The majority of pharmacies (74.3% dispensed antibiotics without prescription with three different levels of demand. The percentage of pharmacies dispensing antibiotics without a prescription for the sore throat scenario was 97.6%, followed by urinary tract infection (83.3%, diarrhea (83%, and otitis media (68.4%. The lowest percentage of antibiotic dispensing was for the acute sinusitis simulation at 48.5%. Among the pharmacies that dispensed antibiotics, the pharmacists provided an explanation as the number of times per day the drug should be taken in 95.3% of the cases, explained the duration of treatment in 25.7%, and inquired about allergies prior to the sale of the antibiotic in only 17.3%. Only 52 pharmacies (25.7% refused to dispense any kind of antibiotics, the majority (61.5% of this refusal response came from acute sinusitis cases, while the minority (2.4% came from the sore throat cases. Conclusion: The results of this study demonstrate that antibiotics continue to be dispensed

  12. Acoustic Cavitation: A Potential Remediation Technology for On-Site Elimination of Perfluorinated Contaminants

    Science.gov (United States)

    Vecitis, C. D.; Cheng, J.; Park, H.; Hoffmann, M. R.

    2006-12-01

    Perfluorinated chemicals are emerging as globally ubiquitous contaminants which are recalcitrant to the conventional remediation techniques of adsorption and chemical oxidation. The release of these chemicals to the environment occurs from specific sites such as manufacturing plants, fire-fighting foams at airports and contaminated landfills. Even though these compounds are widely recognized as potentially hazardous, disposal regulations have been limited due to the ineffectiveness of current pump and treat technologies towards these species. We have shown that ultrasonically induced acoustic cavitation can effectively mineralize aqueous perfluorinated acid and sulfonate species by in situ pyrolysis and chemical oxidation at the lab and pilot scale. Efficiency has been tested on a variety of matrices such as tap water, groundwater and landfill pump-out with VOC content being the major detriment towards remediation. Advanced oxidation by the simultaneously application of ozone and ultrasound seems to partially eliminate this barrier by enhancing the rate of VOC mineralization. Application of this technology to a contaminated field site and the obstacles of scaling to such a degree are discussed.

  13. Atlantic Herring Acoustic Surveys

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NEFSC Advanced Sampling Technologies Research Group conducts annual fisheries acoustic surveys using state-of-the-art acoustic, midwater trawling, and...

  14. Remote erosion and corrosion monitoring of subsea pipelines using acoustic telemetry and wet-mate connector technology

    Energy Technology Data Exchange (ETDEWEB)

    Painter, Howard; Barlow, Stewart [Teledyne ODI, Thousand Oaks, CA (United States); Clarke, Daniel [Teledyne Cormon, Thousand Oaks, CA (United States); Green, Dale [Teledyne Benthos, North Falmouth, MA (United States)

    2009-07-01

    This paper will present a novel approach for monitoring erosion and corrosion using proven sub sea technologies: intrusive erosion and corrosion monitoring, acoustic telemetry and wet-mateable connector technology. Intrusive metal loss based monitoring systems on sub sea pipelines are increasingly being used because of their ability to directly measure erosion and corrosion. These systems are integrated with the sub sea production control system or located close to the platform and hard-wired. However, locations remote from a sub sea control system or platform requires a dedicated communication system and long lengths of cable that can be cost prohibitive to procure and install. The system presented consists of an intrusive erosion or corrosion monitor with pressure and temperature transmitters, a retrievable electronics module with an acoustic modem, a data storage module, and a replaceable power module. Time-stamped erosion and corrosion data can be transmitted via an acoustic link to a surface platform, a vessel of opportunity or to a relaying modem. Acoustic signals can be transmitted up to 6 km from the monitoring location. The power module along with data module and acoustic modem are mounted on the erosion and corrosion module using wet-mateable connectors, allowing retrieval by remotely operated vehicles. The collected data can be used to assess the cumulative erosion and corrosion as well as use the real-time metal loss rate data to correlate with operational parameters. Benefits include optimization of corrosion inhibitor dosage rates, mitigation of damage caused by solids production, and increased flow assurance. (author)

  15. Final developments, validation and technology transfer for AE (acoustic emission) and SAFT-UT (Synthetic Aperture Focusing of Ultrasonic Testing)

    International Nuclear Information System (INIS)

    The program for validation and technology transfer for acoustic emission (AE) and Synthetic Aperture Focusing of Ultrasonic Testing (SAFT-UT) is designed to accomplish the final step of moving research results into beneficial application. Accomplishments for FY88 in the areas of AE and SAFT-UT data under this program are discussed in this paper. the information is treated under the topics of code activities, field validation, and seminars. Projected FY89 activities will continue to focus on these three areas

  16. 改良配药技术对减少输液微粒污染提高输液安全性的研究%Research on improved dispensing technology to reduce infusion particle pollution and raise infusion security

    Institute of Scientific and Technical Information of China (English)

    许美芳; 杨会容; 柏艳; 茹瑞芝; 梁丽珠

    2011-01-01

    目的 探讨安全配药的最优方法,提高配药工作效率.方法 实验组和对照组各30例,对照组按常规方法 配药,实验组采用改良方法 配药,观察两组配药后产生不溶性微粒的数量.结果 实验组产生≥10 μm(个/ml)和≥25μm(个/ml)的数量明显低于对照组(P<0.01),但两组均未达到中国药典标准.结论 改良法配药能减少输液微粒污染,但建立静脉输液配药中心或安装超净工作台配药是非常必要的.%Objective To investigate the optimal method of dispensing safety, and increase work efficacy. Methods The experimental group and control group were collected with 30 cases respectively. The control group was treated with conventional dispensing methods, experimental group improved dispensing method. The number of insoluble particles was observed between the two groups. Results The experimental group showed ≥ 10 microns (a/ml), and ≥ 25 microns (a/ml) than in the control group (P < 0. 01), but both failed to meet the standards of the Chinese Pharmacopoeia. Conclusions The modified method can reduce the transfusion of dispensing particulate pollution, but the establishment of intravenous infusion center or install clean benches pharmacy dispensing is necessary.

  17. Acoustical Imaging

    CERN Document Server

    Akiyama, Iwaki

    2009-01-01

    The 29th International Symposium on Acoustical Imaging was held in Shonan Village, Kanagawa, Japan, April 15-18, 2007. This interdisciplinary Symposium has been taking place every two years since 1968 and forms a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. In the course of the years the volumes in the Acoustical Imaging Series have developed and become well-known and appreciated reference works. Offering both a broad perspective on the state-of-the-art in the field as well as an in-depth look at its leading edge research, this Volume 29 in the Series contains again an excellent collection of seventy papers presented in nine major categories: Strain Imaging Biological and Medical Applications Acoustic Microscopy Non-Destructive Evaluation and Industrial Applications Components and Systems Geophysics and Underwater Imaging Physics and Mathematics Medical Image Analysis FDTD method and Other Numerical Simulations Audience Researcher...

  18. Laboratory {open_quotes}proof of principle{close_quotes} investigation for the acoustically enhanced remediation technology

    Energy Technology Data Exchange (ETDEWEB)

    Iovenitti, J.L.; Spencer, J.W. Jr.; Hill, D.G. [Weiss Associates, Emergyville, CA (United States)] [and others

    1995-10-01

    Weiss Associates is conducting a three phase program investigating the systematics of using acoustic excitation fields (AEFs) to enhance the in-situ remediation of contaminated soil and ground water under both saturated and unsaturated conditions: Phase I - Laboratory Scale Parametric Investigation; Phase II - Technology Scaling Study; and Phase III - Large Scale Field Tests. Phase I, the subject of this paper, consisted primarily of a laboratory proof of principle investigation. The field deployment and engineering viability of acoustically enhanced remediation (AER) technology was also examined. Phase II is a technology scaling study addressing the scale up between laboratory size samples on the order of inches, and the data required for field scale testing, on the order of hundreds of feet. Phase III will consist of field scale testing at an non-industrialized, non-contaminated site and at a contaminated site to validate the technology. Summarized herein are the results of the Phase I {open_quotes}proof-of-principle{close_quotes} investigation, and recommendations for Phase H. A general overview of AER technology along with the plan for the Phase I investigation was presented.

  19. Dispensing Equipment Testing with Mid-Level Ethanol/Gasoline Test Fluid: Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Boyce, K.; Chapin, J. T.

    2010-11-01

    The National Renewable Energy Laboratory's (NREL) Nonpetroleum-Based Fuel Task addresses the hurdles to commercialization of biomass-derived fuels and fuel blends. One such hurdle is the unknown compatibility of new fuels with current infrastructure, such as the equipment used at service stations to dispense fuel into automobiles. The U.S. Department of Energy's (DOE) Vehicle Technology Program and the Biomass Program have engaged in a joint project to evaluate the potential for blending ethanol into gasoline at levels higher than nominal 10 volume percent. This project was established to help DOE and NREL better understand any potentially adverse impacts caused by a lack of knowledge about the compatibility of the dispensing equipment with ethanol blends higher than what the equipment was designed to dispense. This report provides data about the impact of introducing a gasoline with a higher volumetric ethanol content into service station dispensing equipment from a safety and a performance perspective.

  20. An emerging reactor technology for chemical synthesis: surface acoustic wave-assisted closed-vessel Suzuki coupling reactions.

    Science.gov (United States)

    Kulkarni, Ketav; Friend, James; Yeo, Leslie; Perlmutter, Patrick

    2014-07-01

    In this paper we demonstrate the use of an energy-efficient surface acoustic wave (SAW) device for driving closed-vessel SAW-assisted (CVSAW), ligand-free Suzuki couplings in aqueous media. The reactions were carried out on a mmolar scale with low to ultra-low catalyst loadings. The reactions were driven by heating resulting from the penetration of acoustic energy derived from RF Raleigh waves generated by a piezoelectric chip via a renewable fluid coupling layer. The yields were uniformly high and the reactions could be executed without added ligand and in water. In terms of energy density this new technology was determined to be roughly as efficient as microwaves and superior to ultrasound.

  1. Structure optimization of the dispensing house in a combustion train for a thermal bake-out aluminum reduction cell

    Institute of Scientific and Technical Information of China (English)

    WU Chengbo; CHANG Baolong; ZHANG Li; ZHANG Binghuai

    2003-01-01

    The fume bake-out aluminum reduction cell is a novel technology possessing such advantages as easy control for the speed of heating-up, well-distributed temperature, and little cathode and anode oxidation. The key equipment of fume bake-out is a combustion train whose one important part is a dispensing house. This work deals with the numerical model and the flow and temperature fields of the dispensing house, which suggests that uniformity of flow and energy distribution is influenced by the position, shape and direction of the nozzle and cross dimension of dispensing house mainly, but is less influenced by entry speed The parameters of the dispensing house structure are optimised to satisfy the requirements for a combustion train in fume bakeout, and appropriate dimensions are obtained for a dispensing house structure.

  2. Prescription habits of dispensing and non-dispensing doctors in Zimbabwe

    DEFF Research Database (Denmark)

    Trap, Birna; Hansen, Ebba Holme; Hogerzeil, Hans V

    2002-01-01

    . Dispensing doctors also spent significantly less time on each encounter (8.7 min versus 13.0 min) than their non-dispensing colleagues. The use of generic name, brand name and essential drugs did not differ significantly between the two groups of practitioners. Multivariate analyses controlling for gender...

  3. Dispensing an enzyme-conjugated solution into an ELISA plate by adapting ink-jet printers.

    Science.gov (United States)

    Lonini, Luca; Accoto, Dino; Petroni, Silvia; Guglielmelli, Eugenio

    2008-04-24

    The rapid and precise delivery of small volumes of bio-fluids (from picoliters to nanoliters) is a key feature of modern bioanalytical assays. Commercial ink-jet printers are low-cost systems which enable the dispensing of tiny droplets at a rate which may exceed 10(4) Hz per nozzle. Currently, the main ejection technologies are piezoelectric and bubble-jet. We adapted two commercial printers, respectively a piezoelectric and a bubble-jet one, for the deposition of immunoglobulins into an ELISA plate. The objective was to perform a comparative evaluation of the two classes of ink-jet technologies in terms of required hardware modifications and possible damage on the dispensed molecules. The hardware of the two printers was modified to dispense an enzyme conjugate solution, containing polyclonal rabbit anti-human IgG labelled with HRP in 7 wells of an ELISA plate. Moreover, the ELISA assay was used to assess the functional activity of the biomolecules after ejection. ELISA is a common and well-assessed technique to detect the presence of particular antigens or antibodies in a sample. We employed an ELISA diagnostic kit for the qualitative screening of anti-ENA antibodies to verify the ability of the dispensed immunoglobulins to bind the primary antibodies in the wells. Experimental tests showed that the dispensing of immunoglobulins using the piezoelectric printer does not cause any detectable difference on the outcome of the ELISA test if compared to manual dispensing using micropipettes. On the contrary, the thermal printhead was not able to reliably dispense the bio-fluid, which may mean that a surfactant is required to modify the wetting properties of the liquid.

  4. A pipette dispenses a charged droplet

    Science.gov (United States)

    Choi, Dongwhi; Lee, Horim; Im, Do Jin; Kang, In Seok; Kang, Kwan Hyoung

    2012-11-01

    Micropipettes are widely used in many scientific and engineering fields. However, it is hardly known that a droplet dispensed from a plastic pipette tip has a considerable amount of charges (order of 10-10 C). Here we report that the charged droplet is dispensed from a commercial and disposable plastic pipette tip and this charge is originated from the natural electrification between a solution and the inner surface of the pipette tip. The charge amount is dependent on not only the physicochemical properties of a solution (e.g., pH and a concentration) but also dispensing environments (e.g., atmospheric humidity and type of commercial pipette tip). To investigate the effects of the charge on the droplet dispensing, we calculate the electrical force between the droplet and the pipette tip though numerical simulation. The micropipette users especially, who are dealing with discrete droplets in their experiments, should consider this charge effect in their dispensing of a droplet. This work was supported by the National Research Foundation of Korea (NRF) Grant No. R0A-2007-000-20098-0 funded by the Korea government (MEST) and No. 20090083510 through Multiphenomena CFD Engineering Research Center.

  5. Visualization of Surface Acoustic Waves in Thin Liquid Films

    OpenAIRE

    Rambach, R. W.; Taiber, J.; C. M. L. Scheck; Meyer, C.; Reboud, J.; Cooper, J M; Franke, T.

    2016-01-01

    We demonstrate that the propagation path of a surface acoustic wave (SAW), excited with anWe demonstrate that the propagation path of a surface acoustic wave (SAW), excited with an interdigitated transducer (IDT), can be visualized using a thin liquid film dispensed onto a lithium niobate (LiNbO3) substrate. The practical advantages of this visualization method are its rapid and simple implementation, with many potential applications including in characterising acoustic pumping within microfl...

  6. Research on Dispensing Mechanism of Active Code in Active Network

    Institute of Scientific and Technical Information of China (English)

    WANG Jian-guo; LI Zeng-zhi; KOU Ya-nan

    2003-01-01

    The dispensing mechanism of active code is the key technology in active network. Conventional capsule and programmable switch approaches have their own shortcomings. DCCAN mechanism presented in this paper overcomes their shortcomings. In this paper, capsule and programmable switch approaches are introduced and their shortcomings are analyzed. The principle of DCCAN mechanism is described. The theoretical analyses in transmission bandwidth based on DCCAN mechanism and capsule approach are described, and key factors which affect the transmission bandwidth based on DCCAN mechanism are also discussed. At the same time, the theoretical analyses in latency based on DCCAN mechanism and capsule approach are described. The using condition of DCCAN mechanism is also discussed.

  7. Dynamically programmable electronic pill dispenser system.

    Science.gov (United States)

    Boquete, Luciano; Rodriguez-Ascariz, Jose Manuel; Artacho, Irene; Cantos-Frontela, Joaquin; Peixoto, Nathalia

    2010-06-01

    Compliance in medicine dispensation has proven critical for dosage control, diagnosis, and treatment. We have designed, manufactured, and characterized a novel dynamically programmable e-pill dispensing system. Our system is initially programmed remotely through a cell phone. After programming, the system may be reconfigured in order to adapt pill dispensation to new conditions. In this paper we describe the mechanics, electronics, control, and communication protocols implemented. Our dyn-e-pill devices can be actuated for over 350 h with two pill retrievals per hour. We challenged the charging circuit and demonstrated that the system has a lifetime longer than 6 h with a 30 min charging cycle, while it lasts for 14 h of uninterrupted use with a full charge. PMID:20503621

  8. 30 CFR 75.1905 - Dispensing of diesel fuel.

    Science.gov (United States)

    2010-07-01

    ... from other than safety cans must be dispensed by means of— (1) Gravity feed with a hose equipped with a...) An anti-siphoning device. (c) Diesel fuel must not be dispensed using compressed gas. (d) Diesel...

  9. Foam-Mixing-And-Dispensing Machine

    Science.gov (United States)

    Chong, Keith Y.; Toombs, Gordon R.; Jackson, Richard J.

    1996-01-01

    Time-and-money-saving machine produces consistent, homogeneously mixed foam, enhancing production efficiency. Automatically mixes and dispenses polyurethane foam in quantities specified by weight. Consists of cart-mounted, air-driven proportioning unit; air-activated mechanical mixing gun; programmable timer/counter, and controller.

  10. 21 CFR 872.3080 - Mercury and alloy dispenser.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Mercury and alloy dispenser. 872.3080 Section 872...) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices § 872.3080 Mercury and alloy dispenser. (a) Identification. A mercury and alloy dispenser is a device with a spring-activated valve intended to measure...

  11. Measurement of porcine haptoglobin in meat juice using surface acoustic wave biosensor technology.

    Science.gov (United States)

    Klauke, Thorsten N; Gronewold, Thomas M A; Perpeet, Markus; Plattes, Susanne; Petersen, Brigitte

    2013-11-01

    Aim of the study was the application of biosensor technique to measure the concentration of an acute phase protein (APP) within complex matrices from animal origin. For the first time, acute phase protein haptoglobin (Hp) was detected from unpurified meat juice of slaughter pigs by a label-free biosensor-system, the SAW-based sam®5 system. The system uses a sensor chip with specific antibodies to catch Hp while the mass-related phase shift is measured. The concentration is calculated as a function of these measured phase shifts. The results correlate very well with reference measurement results obtained by enzyme-linked immunosorbent assay (ELISA), R=0.98. The robust setup of the surface acoustic wave (SAW)-based system and its ability to measure within very short time periods qualifies it for large-scale analyses and is apt to identify rapidly pigs in the meat production process whose consumption would have an increased risk for consumers.

  12. 粮仓中小麦的声学检测方法研究进展%A Review of Acoustic Detection Technology for the Stored Wheat

    Institute of Scientific and Technical Information of China (English)

    罗松明; 周展明

    2012-01-01

    小麦的贮藏品质关系到粮食的数量安全和质量安全,对小麦品质的声学检测技术的应用研究进行了综述,首先对农产品的声学特性的概念进行了简述,然后从以下几个方面综述了声学检测技术的研究进展:通过采集并分析小麦粉调制面团过程中的声学特性测定不同小麦粉的品质;或采集并分析小麦籽粒在特定装置中的声音信号来达到测定小麦品质的目的;或通过声学方法测定粮食的密度或采集分析粮仓中害虫的声信号来监测粮仓中小麦的贮藏状态.%Quality properties during wheat storage period is vital to food security and safety. In this paper a review of acoustic detection technology for the stored wheat is presented. The definition of acoustic characteristic of agricultural products is reviewed, and then the researches on the acoustic detection technology from several subsequent aspects are summarized: the quality of wheat flour was determined by acquiring and analysising the acoustic signal during dough processing; the quality of wheat was measured by acquiring and analysising the acoustic signal of kernels in a special device; the storage properties of wheat in the granary was predicted by analysising the grain density, or by acquiring and analysising the acoustic signal of pests.

  13. Acoustic vector sensor signal processing

    Institute of Scientific and Technical Information of China (English)

    SUN Guiqing; LI Qihu; ZHANG Bin

    2006-01-01

    Acoustic vector sensor simultaneously, colocately and directly measures orthogonal components of particle velocity as well as pressure at single point in acoustic field so that is possible to improve performance of traditional underwater acoustic measurement devices or detection systems and extends new ideas for solving practical underwater acoustic engineering problems. Although acoustic vector sensor history of appearing in underwater acoustic area is no long, but with huge and potential military demands, acoustic vector sensor has strong development trend in last decade, it is evolving into a one of important underwater acoustic technology. Under this background, we try to review recent progress in study on acoustic vector sensor signal processing, such as signal detection, DOA estimation, beamforming, and so on.

  14. [Economic analysis of strategic behavior in dispensing pharmacies in the separation of dispensing and prescribing functions].

    Science.gov (United States)

    Sakurai, Hidehiko

    2003-03-01

    In recent years, the system for the separation of dispensing and prescribing functions (SDP) has progressed in Japan. However, because of the failure of the healthcare system, it is difficult to estimate how the system of SDP contributes to the improvement of patient utility and welfare. In this paper, I try to evaluate the SDP by analyzing the strategic behavior of dispensing pharmacies, employing some economic models under imperfect information. In these models, quality is characterized as a strategic variable in monopolistic or duopolistic competition. As a result, I show that competition among dispensing pharmacies in the SDP raises the quality of pharmaceutical services, but there is some possibility of "excess entry" with free entry. PMID:12693020

  15. Acoustically enhanced heat transport

    Energy Technology Data Exchange (ETDEWEB)

    Ang, Kar M.; Hung, Yew Mun; Tan, Ming K., E-mail: tan.ming.kwang@monash.edu [School of Engineering, Monash University Malaysia, 47500 Bandar Sunway, Selangor (Malaysia); Yeo, Leslie Y. [Micro/Nanophysics Research Laboratory, RMIT University, Melbourne, VIC 3001 (Australia); Friend, James R. [Department of Mechanical and Aerospace Engineering, University of California, San Diego, California 92093 (United States)

    2016-01-15

    We investigate the enhancement of heat transfer in the nucleate boiling regime by inducing high frequency acoustic waves (f ∼ 10{sup 6} Hz) on the heated surface. In the experiments, liquid droplets (deionized water) are dispensed directly onto a heated, vibrating substrate. At lower vibration amplitudes (ξ{sub s} ∼ 10{sup −9} m), the improved heat transfer is mainly due to the detachment of vapor bubbles from the heated surface and the induced thermal mixing. Upon increasing the vibration amplitude (ξ{sub s} ∼ 10{sup −8} m), the heat transfer becomes more substantial due to the rapid bursting of vapor bubbles happening at the liquid-air interface as a consequence of capillary waves travelling in the thin liquid film between the vapor bubble and the air. Further increases then lead to rapid atomization that continues to enhance the heat transfer. An acoustic wave displacement amplitude on the order of 10{sup −8} m with 10{sup 6} Hz order frequencies is observed to produce an improvement of up to 50% reduction in the surface temperature over the case without acoustic excitation.

  16. Performance Analysis for Dispensing Mechanism of Active Code

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The dispensing mechanism of active code is a key technology in an active network. Conventional capsule and programmable switch approaches have their own shortcomings. The DCCAN(distributed code caching for active network) mechanism presented in this paper overcomes these shortcomings. In this paper, capsule and programmable switch approaches are introduced, and their shortcomings are analyzed. The principle of the DCCAN mechanism is described. The theory analysis in transmit width based on the DCCAN mechanism and capsule approach are described. The theory analysis shows that the DCCAN mechanism has many good characteristics and can improve the efficiency of an active network. Key factors which affect the transmit width based on the DCCAN mechanism are discussed. The using condition of the DCCAN mechanism is also discussed.

  17. Developments in the Implementation of Acoustic Droplet Ejection for Protein Crystallography.

    Science.gov (United States)

    Wu, Ping; Noland, Cameron; Ultsch, Mark; Edwards, Bonnie; Harris, David; Mayer, Robert; Harris, Seth F

    2016-02-01

    Acoustic droplet ejection (ADE) enables crystallization experiments at the low-nanoliter scale, resulting in rapid vapor diffusion equilibration dynamics and efficient reagent usage in the empirical discovery of structure-enabling protein crystallization conditions. We extend our validation of this technology applied to the diverse physicochemical property space of aqueous crystallization reagents where dynamic fluid analysis coupled to ADE aids in accurate and precise dispensations. Addition of crystallization seed stocks, chemical additives, or small-molecule ligands effectively modulates crystallization, and we here provide examples in optimization of crystal morphology and diffraction quality by the acoustic delivery of ultra-small volumes of these cofactors. Additional applications are discussed, including set up of in situ proteolysis and alternate geometries of crystallization that leverage the small scale afforded by acoustic delivery. Finally, we describe parameters of a system of automation in which the acoustic liquid handler is integrated with a robotic arm, plate centrifuge, peeler, sealer, and stacks, which allows unattended high-throughput crystallization experimentation.

  18. Direct-Dispense Polymeric Waveguides Platform for Optical Chemical Sensors

    OpenAIRE

    Mohamad Hajj-Hassan; Timothy Gonzalez; Ebrahim Ghafar-Zadeh; Hagop Djeghelian; Vamsy Chodavarapu; Daniel Therriault; Mark Andrews

    2008-01-01

    We describe an automated robotic technique called direct-dispense to fabricate a polymeric platform that supports optical sensor arrays. Direct-dispense, which is a type of the emerging direct-write microfabrication techniques, uses fugitive organic inks in combination with cross-linkable polymers to create microfluidic channels and other microstructures. Specifically, we describe an application of direct-dispensing to develop optical biochemical sensors by fabricating planar ridge waveguides...

  19. [Experience with an automated dispensing system in department of pharmacy].

    Science.gov (United States)

    Labrosse, H; Duchamp, F; Vantard, N; Darlay, A L; Kohler, A; Sebert, P; Mégard, R

    2010-03-01

    Nominative drug dispensation significantly reduces the incidence of medication errors. Computerized automated unit dose drug distribution system could be a safest hospital drug distribution system and allows an improvement of drug distribution in clinical ward. In 2005, at the Vinatier Hospital, an automated ward dispensing device was acquired. This report describes the implementation of this system and the experience of the pharmacy department. The implementation of an automated unit dose system includes expanding computerized order entry system, physicians' training and nurses to use the software, pharmaceutic staff's training to use the new dispensing system and setting under quality assurance the dispensation process. PMID:20434599

  20. Prescription, dispensation and marketing patterns of methylphenidate

    Directory of Open Access Journals (Sweden)

    Edson Perini

    2014-12-01

    Full Text Available OBJECTIVE To analyze the patterns and legal requirements of methylphenidate consumption. METHODS We conducted a cross-sectional study of the data from prescription notification forms and balance lists of drugs sales – psychoactive and others – subject to special control in the fifth largest city of Brazil, in 2006. We determined the defined and prescribed daily doses, the average prescription and dispensation periods, and the regional sales distribution in the municipality. In addition, we estimated the costs of drug acquisition and analyzed the individual drug consumption profile using the Lorenz curve. RESULTS The balance lists data covered all notified sales of the drug while data from prescription notification forms covered 50.6% of the pharmacies that sold it, including those with the highest sales volumes. Total methylphenidate consumption was 0.37 DDD/1,000 inhabitants/day. Sales were concentrated in more developed areas, and regular-release tablets were the most commonly prescribed pharmaceutical formulation. In some regions of the city, approximately 20.0% of the prescriptions and dispensation exceeded 30 mg/day and 30 days of treatment. CONCLUSIONS Methylphenidate was widely consumed in the municipality and mainly in the most developed areas. Of note, the consumption of formulations with the higher abuse risk was the most predominant. Both its prescription and dispensation contrasted with current pharmacotherapeutic recommendations and legal requirements. Therefore, the commercialization of methylphenidate should be monitored more closely, and its use in the treatment of behavioral changes of psychological disorders needs to be discussed in detail, in line with the concepts of the quality use of medicines.

  1. Acoustic sniper localization system

    Science.gov (United States)

    Prado, Gervasio; Dhaliwal, Hardave; Martel, Philip O.

    1997-02-01

    Technologies for sniper localization have received increased attention in recent months as American forces have been deployed to various trouble spots around the world. Among the technologies considered for this task acoustics is a natural choice for various reasons. The acoustic signatures of gunshots are loud and distinctive, making them easy to detect even in high noise background environments. Acoustics provides a passive sensing technology with excellent range and non line of sight capabilities. Last but not least, an acoustic sniper location system can be built at a low cost with off the shelf components. Despite its many advantages, the performance of acoustic sensors can degrade under adverse propagation conditions. Localization accuracy, although good, is usually not accurate enough to pinpoint a sniper's location in some scenarios (for example which widow in a building or behind which tree in a grove). For these more demanding missions, the acoustic sensor can be used in conjunction with an infra red imaging system that detects the muzzle blast of the gun. The acoustic system can be used to cue the pointing system of the IR camera in the direction of the shot's source.

  2. Improving Pharmacy Dispensing Performance Through Time Management

    OpenAIRE

    Shaat, Mohamed

    2011-01-01

    The aim of this project was to carry out a change model in one of Family Medicine Clinic’s Pharmacy in Abu Dhabi. While, the objectives of the project were to improve patient satisfaction through improving patient waiting time for medications collection, improving patient’s knowledge about the pharmacy services and then generalize the implemented change in all other six clinic’s pharmacies. The change was happened because of current system of dispensing patient’s prescription ‘in turn’, which...

  3. Preliminary study of ultrasonographic tissue quantification of the breast using the acoustic radiation force impulse (ARFI) technology

    Energy Technology Data Exchange (ETDEWEB)

    Tozaki, Mitsuhiro, E-mail: e-tozaki@keh.biglobe.ne.jp [Division of Breast Imaging, Breast Center, Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba 296-8602 (Japan); Isobe, Sachiko, E-mail: 1161003601@jcom.home.ne.jp [Division of Ultrasonographic Examination, Kameda Medical Center 929 Higashi-cho, Kamogawa, Chiba 296-8602 (Japan); Fukuma, Eisuke, E-mail: efosea@gmail.com [Division of Breast Surgery, Breast Center, Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba 296-8602 (Japan)

    2011-11-15

    Highlights: > We confirmed the reproducibility of the Virtual Touch tissue quantification. > Operator dependence is negligible when assessing the stiffness of breast lesions. > Tissue quantification is promising technique for the diagnosis of breast lesions. -- Abstract: Purpose: To investigate the shear wave velocity of normal breast tissue and breast lesion using acoustic radiation force impulse (ARFI) technology. Materials and methods: This retrospective study was conducted with the approval of the institutional review board. Shear wave velocity was measured using a linear array transducer with a bandwidth of 4-9 MHz and Virtual Touch tissue quantification (Siemens Medical Solutions, Mountain View, CA, USA) in 50 patients. First, the values of the shear wave velocity were determined in the normal tissues. Then, the changes in the shear wave velocity while applying external compression on the breast were determined. For the differential diagnosis of breast lesions, the shear wave velocities of 30 mass lesions (13 benign and 17 malignant lesions) classified as BI-RADS category 4 were measured. Results: The mean shear wave velocities in the subcutaneous fat and the mammary gland parenchyma were 2.66 m/s and 3.03 m/s, respectively (p = 0.0006). The mean shear wave velocity measured while applying external compression was 3.33 m/s for subcutaneous fat (p < 0.0001), and 3.84 m/s for the mammary gland parenchyma (p < 0.0001). In 4 of malignant cases, the shear wave velocity was not indicated (displayed as X.XX; unmeasurable state). The mean shear wave velocity of the 13 malignant lesions (4.49 m/s) was higher than that of benign lesions (2.68 m/s) (p < 0.01). Conclusions: ARFI tissue quantification is thought to be a potentially promising ultrasound technique for the diagnosis of breast lesions, but further investigation is required to identify the most appropriate method of measurement.

  4. Acoustic mapping velocimetry

    Science.gov (United States)

    Muste, M.; Baranya, S.; Tsubaki, R.; Kim, D.; Ho, H.; Tsai, H.; Law, D.

    2016-05-01

    Knowledge of sediment dynamics in rivers is of great importance for various practical purposes. Despite its high relevance in riverine environment processes, the monitoring of sediment rates remains a major and challenging task for both suspended and bed load estimation. While the measurement of suspended load is currently an active area of testing with nonintrusive technologies (optical and acoustic), bed load measurement does not mark a similar progress. This paper describes an innovative combination of measurement techniques and analysis protocols that establishes the proof-of-concept for a promising technique, labeled herein Acoustic Mapping Velocimetry (AMV). The technique estimates bed load rates in rivers developing bed forms using a nonintrusive measurements approach. The raw information for AMV is collected with acoustic multibeam technology that in turn provides maps of the bathymetry over longitudinal swaths. As long as the acoustic maps can be acquired relatively quickly and the repetition rate for the mapping is commensurate with the movement of the bed forms, successive acoustic maps capture the progression of the bed form movement. Two-dimensional velocity maps associated with the bed form migration are obtained by implementing algorithms typically used in particle image velocimetry to acoustic maps converted in gray-level images. Furthermore, use of the obtained acoustic and velocity maps in conjunction with analytical formulations (e.g., Exner equation) enables estimation of multidirectional bed load rates over the whole imaged area. This paper presents a validation study of the AMV technique using a set of laboratory experiments.

  5. 14 CFR 137.39 - Economic poison dispensing.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Economic poison dispensing. 137.39 Section... AIRCRAFT OPERATIONS Operating Rules § 137.39 Economic poison dispensing. (a) Except as provided in... economic poison that is registered with the U.S. Department of Agriculture under the Federal...

  6. Evaluation and remediation of bulk soap dispensers for biofilm.

    Science.gov (United States)

    Lorenz, Lindsey A; Ramsay, Bradley D; Goeres, Darla M; Fields, Matthew W; Zapka, Carrie A; Macinga, David R

    2012-01-01

    Recent studies evaluating bulk soap in public restroom soap dispensers have demonstrated up to 25% of open refillable bulk-soap dispensers were contaminated with ~ 6 log(10)(CFU ml(-1)) heterotrophic bacteria. In this study, plastic counter-mounted, plastic wall-mounted and stainless steel wall-mounted dispensers were analyzed for suspended and biofilm bacteria using total cell and viable plate counts. Independent of dispenser type or construction material, the bulk soap was contaminated with 4-7 log(10)(CFU ml(-1)) bacteria, while 4-6 log(10)(CFU cm(-2)) biofilm bacteria were isolated from the inside surfaces of the dispensers (n = 6). Dispenser remediation studies, including a 10 min soak with 5000 mg l(-1) sodium hypochlorite, were then conducted to determine the efficacy of cleaning and disinfectant procedures against established biofilms. The testing showed that contamination of the bulk soap returned to pre-test levels within 7-14 days. These results demonstrate biofilm is present in contaminated bulk-soap dispensers and remediation studies to clean and sanitize the dispensers are temporary.

  7. Hydrodynamic dispensing and electrical manipulation of attolitre droplets

    Science.gov (United States)

    Zhang, Yanzhen; Zhu, Benliang; Liu, Yonghong; Wittstock, Gunther

    2016-08-01

    Dispensing and manipulation of small droplets is important in bioassays, chemical analysis and patterning of functional inks. So far, dispensing of small droplets has been achieved by squeezing the liquid out of a small orifice similar in size to the droplets. Here we report that instead of squeezing the liquid out, small droplets can also be dispensed advantageously from large orifices by draining the liquid out of a drop suspended from a nozzle. The droplet volume is adjustable from attolitre to microlitre. More importantly, the method can handle suspensions and liquids with viscosities as high as thousands mPa s markedly increasing the range of applicable liquids for controlled dispensing. Furthermore, the movement of the dispensed droplets is controllable by the direction and the strength of an electric field potentially allowing the use of the droplet for extracting analytes from small sample volume or placing a droplet onto a pre-patterned surface.

  8. Acoustic Neuroma

    Science.gov (United States)

    An acoustic neuroma is a benign tumor that develops on the nerve that connects the ear to the brain. ... can press against the brain, becoming life-threatening. Acoustic neuroma can be difficult to diagnose, because the ...

  9. Manufacturing polymeric micro lenses and self-organised micro lens arrays by using microfluidic dispensers

    International Nuclear Information System (INIS)

    Micro lenses and micro lens arrays have been widely used in numerous areas. In recent years, direct deposition of micro lenses and micro lens arrays by using drop-on-demand dispensers has been studied. However, the traditional drop-on-demand methods have issues such as expensive facilities and appropriateness for low viscosity materials. In this paper, a novel droplet-based method for fabricating polymeric micro lenses and lens arrays is presented. This method utilises microfluidic devices as dispensers to generate micro- to meso-scale droplets, and uses interfacial forces to control the lens profiles. This new method can create lenses with aperture sizes from 130 μm to 2000 μm for both low and high viscosity materials. It is also capable of fabricating self-organised lens arrays with high fill factors. This technology can simplify the manufacturing process and lower the manufacturing costs of micro lenses and lens arrays. (paper)

  10. Practice and key technology on acoustics design of concert hall%音乐厅声学设计实践与关键技术的探讨

    Institute of Scientific and Technical Information of China (English)

    章奎生; 宋拥民

    2012-01-01

    Development overview on design and construction of professional concert hall since the 1990s in China is summarized in this paper. Acoustics design cases of professional concert hall completed by Zhang Kuisheng acoustical design and research studio over the past decade are described. Then four of those professional concert halls are introduced in detail. Those are Hunan concert hall, concert hall in China conservatory, Beijing, philharmonic hall in Xiamen international conference center and Yangzhou concert hall. Finally, key technologies and factors should be considered in acoustical design of concert halls such as the preferred reverberation time, shape and volume per seat, acoustical material and diffuser design in concert hall are discussed in detail. Those successful experience and suggestions are put forward for discussing.%简述了20世纪90年代以来我国专业音乐厅设计建设的发展概况,介绍了上海章奎生声学设计研究所近十年来承担专业音乐厅工程声学设计实践成果,例举了中国音乐学院音乐厅、厦门国际会议中心音乐厅、湖南群艺馆音乐厅及扬州市音乐厅共4个音乐厅的设计实例,并对专业音乐厅声学设计中的平剖面体型设计、单座容积控制、厅内混响时间参量选择、声场扩散处理及装修材料选择等多个关键技术进行了总结和探讨.

  11. Application of basic pharmacology and dispensing practice of antibiotics in accredited drug-dispensing outlets in Tanzania

    Directory of Open Access Journals (Sweden)

    Minzi OM

    2013-01-01

    Full Text Available OM Minzi,1 VS Manyilizu21Unit of Pharmacology and Therapeutics, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania, 2Logistics System Strengthening Unit, John Snow Inc, Dar es Salaam, TanzaniaBackground: Provision of pharmaceutical services in accredited drug-dispensing outlets (ADDOs in Tanzania has not been reported. This study compared the antibiotics dispensing practice between ADDOs and part II shops, or duka la dawa baridi (DLDBs, in Tanzania.Methodology: This was a cross-sectional study that was conducted in ADDOs and DLDBs. A simulated client method for data collection was used, and a total of 85 ADDOs, located in Mvomero, Kilombero, and Morogoro rural districts, were compared with 60 DLDBs located in Kibaha district. The research assistants posed as simulated clients and requested to buy antibiotics from ADDOs and DLDBs after presenting a case scenario or disease condition. Among the diseases presented were those requiring antibiotics and those usually managed only by oral rehydration salt or analgesics. The simulated clients wanted to know the antibiotics that were available at the shop. The posed questions set a convincing ground to the dispenser either to dispense the antibiotic directly, request a prescription, or refer the patient to a health facility. Proportions were used to summarize categorical variables between ADDOs and DLDBs, and the chi-square test was used to test for statistical difference between the two drug-outlet types in terms of antibiotic-dispensing practice.Results: As many as 40% of trained ADDO dispensers no longer worked at the ADDO shops, so some of the shops employed untrained staff. A larger proportion of ADDOs than DLDBs dispensed antibiotics without prescriptions (P = 0.004. The overall results indicate that there was no difference between the two types of shops in terms of adhering to regulations for dispensing antibiotics. However, in some circumstances, eg

  12. Application of acoustic leak detection technology for the detection and location of leaks in light water reactors

    International Nuclear Information System (INIS)

    This report presents the results of a study to evaluate the adequacy of leak detection systems in light water reactors. The sources of numerous reported leaks and methods of detection have been documented. Research to advance the state of the art of acoustic leak detection is presented, and procedures for implementation are discussed. 14 refs., 70 figs., 10 tabs

  13. NASA/Army Rotorcraft Technology. Volume 2: Materials and Structures, Propulsion and Drive Systems, Flight Dynamics and Control, and Acoustics

    Science.gov (United States)

    1988-01-01

    The Conference Proceedings is a compilation of over 30 technical papers presented which report on the advances in rotorcraft technical knowledge resulting from NASA, Army, and industry research programs over the last 5 to 10 years. Topics addressed in this volume include: materials and structures; propulsion and drive systems; flight dynamics and control; and acoustics.

  14. Principles of musical acoustics

    CERN Document Server

    Hartmann, William M

    2013-01-01

    Principles of Musical Acoustics focuses on the basic principles in the science and technology of music. Musical examples and specific musical instruments demonstrate the principles. The book begins with a study of vibrations and waves, in that order. These topics constitute the basic physical properties of sound, one of two pillars supporting the science of musical acoustics. The second pillar is the human element, the physiological and psychological aspects of acoustical science. The perceptual topics include loudness, pitch, tone color, and localization of sound. With these two pillars in place, it is possible to go in a variety of directions. The book treats in turn, the topics of room acoustics, audio both analog and digital, broadcasting, and speech. It ends with chapters on the traditional musical instruments, organized by family. The mathematical level of this book assumes that the reader is familiar with elementary algebra. Trigonometric functions, logarithms and powers also appear in the book, but co...

  15. Acoustic telemetry.

    Energy Technology Data Exchange (ETDEWEB)

    Drumheller, Douglas Schaeffer; Kuszmaul, Scott S.

    2003-08-01

    Broadcasting messages through the earth is a daunting task. Indeed, broadcasting a normal telephone conversion through the earth by wireless means is impossible with todays technology. Most of us don't care, but some do. Industries that drill into the earth need wireless communication to broadcast navigation parameters. This allows them to steer their drill bits. They also need information about the natural formation that they are drilling. Measurements of parameters such as pressure, temperature, and gamma radiation levels can tell them if they have found a valuable resource such as a geothermal reservoir or a stratum bearing natural gas. Wireless communication methods are available to the drilling industry. Information is broadcast via either pressure waves in the drilling fluid or electromagnetic waves in the earth and well tubing. Data transmission can only travel one way at rates around a few baud. Given that normal Internet telephone modems operate near 20,000 baud, these data rates are truly very slow. Moreover, communication is often interrupted or permanently blocked by drilling conditions or natural formation properties. Here we describe a tool that communicates with stress waves traveling through the steel drill pipe and production tubing in the well. It's based on an old idea called Acoustic Telemetry. But what we present here is more than an idea. This tool exists, it's drilled several wells, and it works. Currently, it's the first and only acoustic telemetry tool that can withstand the drilling environment. It broadcasts one way over a limited range at much faster rates than existing methods, but we also know how build a system that can communicate both up and down wells of indefinite length.

  16. Controllable evaporation of cesium from a dispenser oven

    Science.gov (United States)

    Fantz, U.; Friedl, R.; Fröschle, M.

    2012-12-01

    This instrument allows controlled evaporation of the alkali metal cesium over a wide range of evaporation rates. The oven has three unique features. The first is an alkali metal reservoir that uses a dispenser as a cesium source. The heating current of the dispenser controls the evaporation rate allowing generation of an adjustable and stable flow of pure cesium. The second is a blocking valve, which is fully metallic as is the body of the oven. This construction both reduces contamination of the dispenser and enables the oven to be operated up to 300 °C, with only small temperature variations (metal at a cold spot is significantly hindered. The last feature is an integral surface ionization detector for measuring and controlling the evaporation rate. The dispenser oven can be easily transferred to the other alkali-metals.

  17. Drug dispensing errors in a ward stock system

    DEFF Research Database (Denmark)

    Andersen, Stig Ejdrup

    2010-01-01

    The aim of this study was to determine the frequency of drug dispensing errors in a traditional ward stock system operated by nurses and to investigate the effect of potential contributing factors. This was a descriptive study conducted in a teaching hospital from January 2005 to June 2007. In five....... These results indicate that strategies to reduce dispensing errors should address polypharmacy and focus on high-risk units. This should, however, be substantiated by a future trial....

  18. Acoustic textiles

    CERN Document Server

    Nayak, Rajkishore

    2016-01-01

    This book highlights the manufacturing and applications of acoustic textiles in various industries. It also includes examples from different industries in which acoustic textiles can be used to absorb noise and help reduce the impact of noise at the workplace. Given the importance of noise reduction in the working environment in several industries, the book offers a valuable guide for companies, educators and researchers involved with acoustic materials.

  19. Comparative Study of Shear Wave Velocities Using Acoustic Radiation Force Impulse Technology in Hepatocellular Carcinoma: The Extent of Radiofrequency Ablation

    OpenAIRE

    Kang, Jiyoung; Kwon, Heejin; Cho, Jinhan; Oh, Jongyoung; Nam, Kyungjin; Yoon, Seongkuk; Kang, Myongjin; Lee, Sungwook; Han, Sangyeong

    2012-01-01

    Background/Aims The purpose of this study was to assess the value of acoustic radiation force impulse (ARFI) for predicting the extent of radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC) by correlating the elasticity of HCC and peritumoral parenchyma (as measured by ARFI) with the extent of ablation determined by computed tomography (CT). Methods From September 2009 to June 2011, 158 patients underwent RFA ablation for HCC (single, ≤3 cm). We evaluated the data of a total of 38...

  20. Ask Your Doctor or Pharmacist! On the Effect of Self-Dispensing Physicians on Pharmaceutical Coverage

    OpenAIRE

    Bannert, Matthias; Iselin, David

    2015-01-01

    In most developed countries drugs are dispensed to patients through physicians and pharmacists. This paper studies the effects of allowing doctors to directly dispense drugs to patients (self-dispensation) on pharmaceutical coverage. We use a Swiss dataset in our empirical analysis because Switzerland's federalist legislation allows us to study self-dispensing and non-self-dispensing regimes alike. We add location information obtained from Google Geocoding services to our dataset in order to ...

  1. Radiation acoustics

    CERN Document Server

    Lyamshev, Leonid M

    2004-01-01

    Radiation acoustics is a developing field lying at the intersection of acoustics, high-energy physics, nuclear physics, and condensed matter physics. Radiation Acoustics is among the first books to address this promising field of study, and the first to collect all of the most significant results achieved since research in this area began in earnest in the 1970s.The book begins by reviewing the data on elementary particles, absorption of penetrating radiation in a substance, and the mechanisms of acoustic radiation excitation. The next seven chapters present a theoretical treatment of thermoradiation sound generation in condensed media under the action of modulated penetrating radiation and radiation pulses. The author explores particular features of the acoustic fields of moving thermoradiation sound sources, sound excitation by single high-energy particles, and the efficiency and optimal conditions of thermoradiation sound generation. Experimental results follow the theoretical discussions, and these clearl...

  2. Survey on Node Localization Technology of Underwater Acoustic Sensor Networks%水声传感器网络节点定位技术综述

    Institute of Scientific and Technical Information of China (English)

    黎作鹏; 蔡绍滨; 张菁; 高振国; 赵靖

    2012-01-01

    In the applications of UASNs(Underwater Acoustic Sensor Networks), only when the sensor node's location is known, the information obtained have meaning. Therefore, the node localization technology is the priorities and hot spots of research of UASNs. First, this paper is to analyze the characteristics of node localization technology in the underwater acoustic environment; then to introduce the classification of range-free and range-based localization algorithm, in which the ranging technology、fixed anchor node based algorithm and mobile anchor node based algorithm of range-based algorithm are focused on and analyzed; finally, the developing and researching direction of node localization technology of UASNs are summarized and foreseen.%在水声传感器网络的应用中,只有当传感器节点的位置已知,获得的信息才具有意义.因此,节点定位技术是水声传感器网络研究的一个重点和热点.首先分析了在水声环境中的传感器网络节点定位技术的特点;在此基础上分类介绍了距离无关定位算法和距离相关定位算法,其中重点阐述和分析了距离相关算法的测距技术、基于固定锚节点算法和基于移动锚节点算法;最后总结并展望了水声传感器网络节点定位技术的发展与研究方向.

  3. Improvement of optical and acoustical technologies for the protection: Project IMOTEP: Network of heterogeneous sensor types for the protection of camps or mobile troops

    Science.gov (United States)

    Hengy, Sébastien; Laurenzis, Martin; Zimpfer, Véronique; Schneider, Armin

    2014-10-01

    Snipers have emerged as a major threat to troops in recent conflicts. To reduce this menace, the objective of the French- German Research Institute of Saint Louis (ISL) research project "IMOTEP" is to improve the detection of snipers on the battlefield. Our basic approach is to combine several sources of information for a fast and appropriate reaction when an unusual signal (e.g. a flash or a shot) is detected. The project includes several technologies developed at ISL: acoustical detection, fusion of distributed sensor network data, active imaging and 3D audio communication. The protection of camps, convoys or dismounted soldiers rests on a distributed acoustical sensor network that detects and localizes sniper attacks. An early estimation of the threat position is transmitted through a network to an active imaging system in order to confirm and refine this position by 3D imaging. The refined position is then sent to the control center which generates an alert message that displays the threat position using two formats: a tactical map and a 3D audio signal. In addition, the camp is protected by an ad-hoc sensor network used for intruder detection.

  4. Acoustic emission signal processing technology and its application in rolling bearing test%声发射信号处理技术及其在滚动轴承检测中的应用现状

    Institute of Scientific and Technical Information of China (English)

    焦阳; 侯洁; 李光海; 吴占稳; 陈晨; 米尚言

    2013-01-01

    声发射技术在滚动轴承的检测中得到了广泛应用,声发射信号处理是检测中的关键技术问题,常用的声发射信号处理技术有参数分析、波形分析、小波分析、模式识别等等.综述了21世纪以来声发射信号处理技术在滚动轴承检测中应用现状,国内外学者在将各种声发射信号处理技术应用于滚动轴承检测方面做了大量研究且取得了一定程度上的研究成果.需要进一步研究的内容是规范各种工况下声发射信号处理方法并设计标准的声发射信号处理平台.%Acoustic emission technology is widely used in rolling bearing test,while the processing technology of acoustic emission signal is essential to the test.The common acoustic emission signal processing technology includes parameter analysis,waveform analysis,wavelet analysis,pattern recognition,etc.This paper gives an overview of acoustic emission signal processing technology in rolling bearing test since year 2000.A lot of research and achievements have been made in the field.And it shows further study should focus on regulating acoustic emission signal processing methods under various working conditions,and the designing of standard acoustic emission signal processing platform.

  5. 声波清灰技术的理论研究与仿真%Simulation and Theoretical Study on Acoustic Wave Ash %learing Technology

    Institute of Scientific and Technical Information of China (English)

    王涌; 郑博闻; 王威

    2011-01-01

    The frequency selecting of wave and energy controlling are the main problems in acoustic wave ash clearing technology. We found that soud intensity is concerned with the frequency of sound generator and the temperature of fluid gas when using the technology. In order to improve the effect of the technology, we built a mathematic model based on the acoustic wave ash clearing technology, and carried out some analyses on theory. Aim to reach the max of sound intensity, the temperature of fluid gas and the frequency of sound generator were improved optimally. The result shows that by Matlab simulating, 200Hz is considered the best frequency for sound intensity between 20 and 200 Hz. And between 0 and 100℃, 0℃ is considered the best the temperature of fluid gas for sound intensity. With the increase of the temperature, the sound intensity decreased. If we increase the frequency, the sound intensity increases evidently. It is very meaningful to research the sound clearing technology of the ESP.%研究声波清灰优化控制除灰效果,能量的控制和频率的选择是目前声波清灰技术研究过程中存在的主要问题.针对声波清灰技术在使用时,声强主要受到声波频率和气体温度因素的影响.为了改善声波清灰技术的效率,对声波清灰技术进行了数学建模和理论研究分析,取得了声强最佳时的气体温度值和声波发生器频率值.在Matlab上仿真结果表明:在20-200Hz范围内,200Hz是声强最大的频率,在0-100℃下,气体温度为O℃时,声强达到最大值.从能量仿真分析结果表明,最佳声频会使声波清灰效果最好.

  6. Acoustics waves and oscillations

    CERN Document Server

    Sen, S.N.

    2013-01-01

    Parameters of acoustics presented in a logical and lucid style Physical principles discussed with mathematical formulations Importance of ultrasonic waves highlighted Dispersion of ultrasonic waves in viscous liquids explained This book presents the theory of waves and oscillations and various applications of acoustics in a logical and simple form. The physical principles have been explained with necessary mathematical formulation and supported by experimental layout wherever possible. Incorporating the classical view point all aspects of acoustic waves and oscillations have been discussed together with detailed elaboration of modern technological applications of sound. A separate chapter on ultrasonics emphasizes the importance of this branch of science in fundamental and applied research. In this edition a new chapter ''Hypersonic Velocity in Viscous Liquids as revealed from Brillouin Spectra'' has been added. The book is expected to present to its readers a comprehensive presentation of the subject matter...

  7. RUN TO RUN CONTROL OF TIME-PRESSURE DISPENSING SYSTEM

    Institute of Scientific and Technical Information of China (English)

    Zhao Yixiang; Li Hanxiong; Ding Han; Xiong Youlun

    2004-01-01

    In electronics packaging the time-pressure dispensing system is widely used to squeeze the adhesive fluid in a syringe onto boards or sub-strates with the pressurized air.However,complexity of the process,which includes the air-fluid coupling and the nonlinear uncertainties,makes it diffi-cult to have a consistent process per-formance.An integrated dispensing process model is first introduced and then its input-output regression rela-tionship is used to design a run to run control methodology for this process.The controller takes EWMA scheme and its stability region is given.Ex-perimental results verify the effective-ness of the proposed run to run control method for dispensing process.

  8. Room Acoustics

    Science.gov (United States)

    Kuttruff, Heinrich; Mommertz, Eckard

    The traditional task of room acoustics is to create or formulate conditions which ensure the best possible propagation of sound in a room from a sound source to a listener. Thus, objects of room acoustics are in particular assembly halls of all kinds, such as auditoria and lecture halls, conference rooms, theaters, concert halls or churches. Already at this point, it has to be pointed out that these conditions essentially depend on the question if speech or music should be transmitted; in the first case, the criterion for transmission quality is good speech intelligibility, in the other case, however, the success of room-acoustical efforts depends on other factors that cannot be quantified that easily, not least it also depends on the hearing habits of the listeners. In any case, absolutely "good acoustics" of a room do not exist.

  9. Battlefield acoustics

    CERN Document Server

    Damarla, Thyagaraju

    2015-01-01

    This book presents all aspects of situational awareness in a battlefield using acoustic signals. It starts by presenting the science behind understanding and interpretation of sound signals. The book then goes on to provide various signal processing techniques used in acoustics to find the direction of sound source, localize gunfire, track vehicles, and detect people. The necessary mathematical background and various classification and fusion techniques are presented. The book contains majority of the things one would need to process acoustic signals for all aspects of situational awareness in one location. The book also presents array theory, which is pivotal in finding the direction of arrival of acoustic signals. In addition, the book presents techniques to fuse the information from multiple homogeneous/heterogeneous sensors for better detection. MATLAB code is provided for majority of the real application, which is a valuable resource in not only understanding the theory but readers, can also use the code...

  10. Acoustics Research

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Fisheries acoustics data are collected from more than 200 sea-days each year aboard the FRV DELAWARE II and FRV ALBATROSS IV (decommissioned) and the FSV Henry B....

  11. Acoustics Discipline Overview

    Science.gov (United States)

    Envia, Edmane; Thomas, Russell

    2007-01-01

    As part of the Fundamental Aeronautics Program Annual Review, a summary of the progress made in 2007 in acoustics research under the Subsonic Fixed Wing project is given. The presentation describes highlights from in-house and external activities including partnerships and NRA-funded research with industry and academia. Brief progress reports from all acoustics Phase 1 NRAs are also included as are outlines of the planned activities for 2008 and all Phase 2 NRAs. N+1 and N+2 technology paths outlined for Subsonic Fixed Wing noise targets. NRA Round 1 progressing with focus on prediction method advancement. NRA Round 2 initiating work focused on N+2 technology, prediction methods, and validation. Excellent partnerships in progress supporting N+1 technology targets and providing key data sets.

  12. Dispensing physicians and prescribing pharmacists: economic considerations for the UK.

    Science.gov (United States)

    Ryan, M; Bond, C

    1994-01-01

    Recent years have seen an increase in the number of dispensing physicians in the UK. There have also been suggestions that legislation restricting certain drugs to prescription-only availability should be relaxed and that pharmacists should take a more active role in the provision of drugs. General medical practitioners and pharmacists have common ancestry in the medieval spicers, who dispensed medicines and offered medical advice. Rural practitioners have been allowed to dispense drugs since 1911. Physician dispensing can benefit patients via savings in time and the monetary cost of visiting a pharmacist, but it restricts drug choice, can compromise safety, and encourages overprescribing except for physicians with drugs budgets. The effects of physician dispensing on government costs are not yet clear. Over-the-counter (OTC) purchase can save patients the cost of a physician visit and reduce drug costs to some patients, but it can also provide an incentive to pharmacists to profit twice from a drug, at government expense. Switching drugs from prescription-only to OTC reduces the government drug bill, but provides an incentive to pharmacists to overprescribe, and may not be as safe for patients. Liberalising prescribing by doctors would discourage community pharmacies which provide an advisory service to patients. Liberalising OTC switches would reduce opportunistic assessment of patients by doctors and could compromise patient safety. Separation of physician and pharmacist functions is probably safer for patients. It is concluded that the current situation in the UK, whereby most dispensing is done by pharmacists, is the preferred option other than for those patients who do not live within easy access of a pharmacy. A reassessment of the legal status of drugs and subsequent OTC switch of drugs used to treat minor self-limiting illnesses is also favoured. PMID:10146862

  13. Overcoming Barriers to the Implementation of a Pharmacy Bar Code Scanning System for Medication Dispensing: A Case Study

    OpenAIRE

    Nanji, Karen C.; Cina, Jennifer; Patel, Nirali; Churchill, William; Gandhi, Tejal K.; Poon, Eric G.

    2009-01-01

    Technology has great potential to reduce medication errors in hospitals. This case report describes barriers to, and facilitators of, the implementation of a pharmacy bar code scanning system to reduce medication dispensing errors at a large academic medical center. Ten pharmacy staff were interviewed about their experiences during the implementation. Interview notes were iteratively reviewed to identify common themes. The authors identified three main barriers to pharmacy bar code scanning s...

  14. Frequency, types, and potential clinical significance of medication-dispensing errors

    OpenAIRE

    Xavier Bohand; Laurent Simon; Eric Perrier; Hélène Mullot; Leslie Lefeuvre; Christian Plotton

    2009-01-01

    INTRODUCTION AND OBJECTIVES: Many dispensing errors occur in the hospital, and these can endanger patients. The purpose of this study was to assess the rate of dispensing errors by a unit dose drug dispensing system, to categorize the most frequent types of errors, and to evaluate their potential clinical significance. METHODS: A prospective study using a direct observation method to detect medication-dispensing errors was used. From March 2007 to April 2007, “errors detected by pharmacists” ...

  15. Integration of BST varactors with surface acoustic wave device by film transfer technology for tunable RF filters

    International Nuclear Information System (INIS)

    This paper presents a film transfer process to integrate barium strontium titanate (BST) metal–insulator–metal (MIM) structures with surface acoustic wave (SAW) devices on a lithium niobate (LN) substrate. A high-quality BST film grown on a Si substrate above 650 °C was patterned into the MIM structures, and transferred to a LN substrate below 130 °C by Ar-plasma-activated Au–Au bonding and the Si lost wafer process. Simple test SAW devices with the transferred BST variable capacitors (VCs) were fabricated and characterized. The resonance frequency of a one-port SAW resonator with the VC connected in series changed from 999 to 1018 MHz, when a dc bias voltage of 3 V was applied to the VC. Although the observed frequency tuning range was smaller than expected due to the degradation of BST in the process, the experimental result demonstrated that a tunable SAW filter with the transferred BST VCs was feasible. (paper)

  16. A microfluidic AFM cantilever based dispensing and aspiration platform

    NARCIS (Netherlands)

    Van Oorschot, R.; Perez Garza, H.H.; Derks, R.J.S.; Staufer, U.; Ghatkesar, M.K.

    2015-01-01

    We present the development of a microfluidic AFM (atomic force microscope) cantilever-based platform to enable the local dispensing and aspiration of liquid with volumes in the pico-to-femtoliter range. The platform consists of a basic AFM measurement system, microfluidic AFM chip, fluidic interface

  17. Fabrication of Microdots Using Piezoelectric Dispensing Technique for Viscous Fluids

    Directory of Open Access Journals (Sweden)

    Ho-Lin Tsai

    2015-10-01

    Full Text Available A simple microfluidic control method that uses a piezoelectric dispenser head is developed to fabricate microdots. A glycerol mixture was used as the test fluid to simulate conductive metallic solutions. The orifice diameter of the dispenser was 50 μm. Investigations were conducted at room temperature (25 °C. For each bipolar waveform, fluid was extruded in the form of a stretching liquid column, which eventually retracted into the dispenser orifice. Microdots were obtained by governing the liquid transfer process between the dispenser orifice and the target surface, where the gap was smaller than the maximum extrusion length during liquid column formation. Three fluid behaviors were observed using high-speed imaging, namely extrusion, impact on the target surface, and pinch-off of liquid ligament. For gaps of below 70 μm, some of the fluid sticking on the target surface resulted in a microdot diameter of 26 μm (about half of the orifice diameter.

  18. Bacterial contamination in cold water samples obtained from water dispensers.

    Science.gov (United States)

    Furuhata, Katsunori; Ishizaki, Naoto; Fukuyama, Masafumi

    2015-01-01

    We carried out a basic study in order to evaluate the bacterial contamination in water dispensers. Water samples were obtained from water dispensers from October 2012 to November 2013, and standard plate counts (at 36˚C, 24 h) of the samples, as well as heterotrophic plate counts (at 25˚C, 7 d), were estimated with the standard methods for the examination of drinking water in Japan. Standard plate counts exceeding the water-quality standard (1.0×10(2) CFU/ml) were observed in 42 of the 140 samples (30.0%), with a maximum detected bacterial count of 2.1×10(5) CFU/ml. The rate of the standard plate counts exceeding the water quality standard tended to be higher when using a one-way type method or water dispensers with natural water. Ralstonia spp. was most commonly isolated, and Pseudomonas aeruginosa was isolated in a few cases. Some opportunistic pathogens were also isolated, suggesting that we should be more concerned about bacterial contamination in cold water supplied from water dispensers.

  19. 21 CFR 866.2500 - Microtiter diluting and dispensing device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Microtiter diluting and dispensing device. 866.2500 Section 866.2500 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Microbiology Devices §...

  20. 21 CFR 200.50 - Ophthalmic preparations and dispensers.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Ophthalmic preparations and dispensers. 200.50... (CONTINUED) DRUGS: GENERAL GENERAL Requirements for Specific Classes of Drugs § 200.50 Ophthalmic... intended for ophthalmic use, including preparations for cleansing the eyes, should be sterile. It...

  1. Acoustic biosensors.

    Science.gov (United States)

    Fogel, Ronen; Limson, Janice; Seshia, Ashwin A

    2016-06-30

    Resonant and acoustic wave devices have been researched for several decades for application in the gravimetric sensing of a variety of biological and chemical analytes. These devices operate by coupling the measurand (e.g. analyte adsorption) as a modulation in the physical properties of the acoustic wave (e.g. resonant frequency, acoustic velocity, dissipation) that can then be correlated with the amount of adsorbed analyte. These devices can also be miniaturized with advantages in terms of cost, size and scalability, as well as potential additional features including integration with microfluidics and electronics, scaled sensitivities associated with smaller dimensions and higher operational frequencies, the ability to multiplex detection across arrays of hundreds of devices embedded in a single chip, increased throughput and the ability to interrogate a wider range of modes including within the same device. Additionally, device fabrication is often compatible with semiconductor volume batch manufacturing techniques enabling cost scalability and a high degree of precision and reproducibility in the manufacturing process. Integration with microfluidics handling also enables suitable sample pre-processing/separation/purification/amplification steps that could improve selectivity and the overall signal-to-noise ratio. Three device types are reviewed here: (i) bulk acoustic wave sensors, (ii) surface acoustic wave sensors, and (iii) micro/nano-electromechanical system (MEMS/NEMS) sensors. PMID:27365040

  2. 46 CFR 105.05-1 - Commercial fishing vessels dispensing petroleum products.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Commercial fishing vessels dispensing petroleum products... MISCELLANEOUS VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Application § 105.05-1 Commercial fishing vessels dispensing petroleum products. (a) The provisions of this part, with the exception...

  3. 46 CFR 105.45-1 - Loading or dispensing petroleum products.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Loading or dispensing petroleum products. 105.45-1... VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Special Operating Requirements § 105.45-1 Loading or dispensing petroleum products. (a) A commercial fishing vessel must have aboard a letter...

  4. 46 CFR 105.90-1 - Existing commercial fishing vessels dispensing petroleum products.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Existing commercial fishing vessels dispensing petroleum... AND MISCELLANEOUS VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Existing Commercial Fishing Vessels Dispensing Petroleum Products § 105.90-1 Existing commercial fishing vessels...

  5. 14 CFR 23.1447 - Equipment standards for oxygen dispensing units.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Equipment standards for oxygen dispensing... Equipment Miscellaneous Equipment § 23.1447 Equipment standards for oxygen dispensing units. If oxygen... occupant for whom supplemental oxygen is to be supplied. Each dispensing unit must: (1) Provide...

  6. 14 CFR 25.1447 - Equipment standards for oxygen dispensing units.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Equipment standards for oxygen dispensing... § 25.1447 Equipment standards for oxygen dispensing units. If oxygen dispensing units are installed... supplemental oxygen is to be supplied. Units must be designed to cover the nose and mouth and must be...

  7. Acoustic emission

    International Nuclear Information System (INIS)

    This paper is related to our activities on acoustic emission (A.E.). The work is made with different materials: metals and fibre reinforced plastics. At present, acoustic emission transducers are being developed for low and high temperature. A test to detect electrical discharges in electrical transformers was performed. Our experience in industrial tests to detect cracks or failures in tanks or tubes is also described. The use of A.E. for leak detection is considered. Works on pattern recognition of A.E. signals are also being performed. (Author)

  8. Modeling and Control of Time-pressure Dispensing for Semiconductor Manufacturing

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    To improve the consistency of the adhesive amount dispensed by the time-pressure dispenser for semiconductor manufacturing, a non-Newtonian fluid flow rate model is developed to represent and estimate the adhesive amount dispensed in each cycle. Taking account of gas compressibility, an intelligent model-based control strategy is proposed to compensate the deviation of adhesive amount dispensed from the desired one. Both simulations and experiments show that the dispensing consistency is greatly improved by using the model-based control strategy developed in this paper.

  9. Antibiotics dispensing for URTIs by community pharmacists and general medical practitioners in Penang, Malaysia: A comparative study using simulated patients

    OpenAIRE

    Alabid, Alamin Hassan M.A.; Ibrahim, Mohamed Izham Mohamed; Hassali, Mohamed Azmi

    2014-01-01

    Background: In Malaysia, doctors in private clinics (often called dispensing doctors) are permitted to dispense medicines. This potentially may compromise rational dispensing of medicines in general and antibiotics in particular. Aim: This study explored, assessed and compared dispensing of antibiotics between Community Pharmacist (CP) and General Practitioners (GPs) regarding symptomatic diagnosis, antibiotic categories, adherence to therapeutic doses and promotion of generic antibiotics...

  10. Continued Dispensing: what medications do patients believe should be available?

    OpenAIRE

    Salem Hasn Abukres; Kreshnik Hoti; Jeffery David Hughes

    2015-01-01

    Background. Continued Dispensing (CD) is a new medication supply method for certain medications in Australia. It aims to prevent treatment interruption as a result of patients’ inability to obtain a new valid prescription. The only currently eligible patients for this service are statin and/or oral contraceptives users who have been using these medications for 6 months or more, have not utilized the CD method during the last 12 months, and cannot obtain an immediate appointment with the presc...

  11. Patient attitudes towards a new role for pharmacists: continued dispensing

    OpenAIRE

    Abukres SH; Hoti K; Hughes JD

    2014-01-01

    Salem Hasn Abukres, Kreshnik Hoti, Jeffery David Hughes School of Pharmacy, Curtin Health and Innovation Research Institute, Curtin University, Perth, WA, Australia Background: In Australia, “continued dispensing” (CD) is a new model for supply of prescription medications. Under specific circumstances, community pharmacists are allowed to dispense a further one month supply of prescription only medications without a valid prescription. It allows continuation and treatment adhere...

  12. Work function measurements of dispenser cathodes by retarding potential method

    Science.gov (United States)

    Khairnar, Rajendra S.; Chopra, A. K.

    1992-11-01

    The work function of dispenser cathode pellets has been determined by means of the retarding potential technique. A low-energy electron gun was fabricated which delivers a collimated beam of electrons on the pellet surface at normal incidence. The set up is calibrated by employing samples of known work function such as gold and tungsten, prior to determining the work function of the cathode pellets. This set up provides a rapid determination of the work function of cathode pellets.

  13. Justice dispensation through the alternative dispute resolution system in India

    OpenAIRE

    Krishna Agrawal

    2014-01-01

    The Law Commission of India in its 222nd report emphasized the need for Alternative Disputes Resolution (ADR) for the dispensation of justice, because the courts are inaccessible owing to various factors, e.g., poverty, social and political backwardness, illiteracy, ignorance, procedural formalities and inordinate delay in judgments. During the ancient period the disputes were resolved in an informal manner by neutral third persons or people’s court in villages and it continued till the middl...

  14. International Space Station USOS Potable Water Dispenser Development

    Science.gov (United States)

    Shaw, Laura A.; Barreda, Jose L.

    2008-01-01

    The International Space Station (ISS) Russian Segment currently provides potable water dispensing capability for crewmember food and beverage rehydration. All ISS crewmembers rehydrate Russian and U.S. style food packages from this location. A new United States On-orbit Segment (USOS) Potable Water Dispenser (PWD) is under development. This unit will provide additional potable water dispensing capability to support an onorbit crew of six. The PWD is designed to provide incremental quantities of hot and ambient temperature potable water to U.S. style food packages. It will receive iodinated water from the Fuel Cell Water Bus in the U.S. Laboratory element. The unit will provide potable-quality water, including active removal of biocidal iodine prior to dispensing. A heater assembly contained within the unit will be able to supply up to 2.0 liters of hot water (65 to 93oC) every thirty minutes. This quantity will allow three to four crewmembers to rehydrate their food and beverages from this location during a single meal. The unit is designed to remain functional for up to ten years with replacement of limited life items such as filters. It will be the size of two stacked Shuttle Middeck lockers (approximately the size of two small suitcases) and integrated into a science payload rack in the U.S. Laboratory element. Providing potable-quality water at the proper temperature for food and beverage reconstitution is critical to maintaining crew health and well-being. The numerous engineering challenges as well as human factors and safety considerations during the concept, design, and prototyping are outlined in this paper.

  15. Private pharmacy staff in Hanoi dispensing steroids - theory and practice

    Directory of Open Access Journals (Sweden)

    Larsson M

    2006-06-01

    Full Text Available Objective: To investigate self reported practice and actual practice of private pharmacy staff in relation to drug regulations and provision of prednisolone (a prescription-only corticosteroid on request to treat lower back pain. Method: Sixty private pharmacies in Hanoi were randomly selected. Self reported practice was assessed through interviews with pharmacy staff using a questionnaire; actual practice was assessed with the Simulated Client Method with 5 encounters in each pharmacy (a total of 295 encounters. Results: Sixty percent of the pharmacy staff interviewed said that they would not dispense corticosteroids without prescription and 60% could mention some adverse effects. In practice all but one pharmacy dispensed corticosteroids without prescription in 76 % of all the encounters. Questions and advice given to the clients were associated with significantly lower dispensing of corticosteroids. Conclusion: The low compliance with prescription regulations and the discrepancy between stated practice and actual practice raises concerns. This study indicates that commercial pressures exceed the deterrent effect of current drug regulations and their implementation and hence enforcement of regulations needs to be improved.

  16. Direct-Dispense Polymeric Waveguides Platform for Optical Chemical Sensors

    Directory of Open Access Journals (Sweden)

    Mohamad Hajj-Hassan

    2008-12-01

    Full Text Available We describe an automated robotic technique called direct-dispense to fabricate a polymeric platform that supports optical sensor arrays. Direct-dispense, which is a type of the emerging direct-write microfabrication techniques, uses fugitive organic inks in combination with cross-linkable polymers to create microfluidic channels and other microstructures. Specifically, we describe an application of direct-dispensing to develop optical biochemical sensors by fabricating planar ridge waveguides that support sol-gelderived xerogel-based thin films. The xerogel-based sensor materials act as host media to house luminophore biochemical recognition elements. As a prototype implementation, we demonstrate gaseous oxygen (O2 responsive optical sensors that operate on the basis of monitoring luminescence intensity signals. The optical sensor employs a Light Emitting Diode (LED excitation source and a standard silicon photodiode as the detector. The sensor operates over the full scale (0%-100% of O2 concentrations with a response time of less than 1 second. This work has implications for the development of miniaturized multisensor platforms that can be cost-effectively and reliably mass-produced.

  17. 多路水声信号抗串漏检测技术仿真%Technology simulation study on detection of anti-cross-leakage from multi-path underwater acoustic signals

    Institute of Scientific and Technical Information of China (English)

    杜召平; 张强; 刘百峰

    2012-01-01

    根据水下多目标定位系统水声通道特点和系统海上试验实际应用情况,建立系统多路合作水声信号检测处理仿真模型.仿真表明:采用FIR宽带滤波器、Notch滤波器组和瞬时频率方差序列等水声信号处理技术,能有效克服系统水声通道串漏、高斯白噪声和鱼雷寻的噪声对信号检测的影响,实现系统对多路合作水声信号的检测处理.%A simulation model is established for the system to detect and process multi-path cooperative underwater acoustic signals according to the characteristic of the underwater acoustic channels for an underwater multi-target positioning system and the practical application for the system sea trial. The simulation indicates that utilizing underwater acoustic signal processing technology, such as FIR wideband filter, Notch filter group and instantaneous frequency variance sequence etc, influences on signal detection can be overcome for cross-leakage from the underwater acoustic channels of the system, Gauss white noises and torpedo homing noises. Detection and processing of multi-path cooperative underwater signals can be implemented by the system.

  18. Technology research and development for acoustic subbottom survey in deep sea%声学地层剖面深水探测研究与开发

    Institute of Scientific and Technical Information of China (English)

    丁维凤; 李家彪; 苏希华; 张济博; 蒋维杰; 韩富江

    2015-01-01

    Detailed survey of acoustic subbottom is important for deep ocean geological exploration and resource ex-ploitation.Compared to survey in shallow ocean water,deep sea survey faced some serious problems such as energy strongly attenuation,long reflection time series and large digital data size,the vertical stratigraphic resolution reduc-tion,and low transverse space coverage.In order to resolving these problems,main instrument manufactures in the world adopted different possible methods.For example,resampling long reflection time series can decrease the data size,but it strongly reduce vertical stratigraphic resolution.Taking MultiPing technology can solve the transverse space coverage well,but its variable depth range acquisition by seafloor reflection tracking will cause serious jump-ing off in reflection events,or it cannot get the correct seafloor reflection depth by acquisition with MultiPing trans-mitting interval.This study further independently developed some related technologies,and correctly solved the re-flection events'jumping off,and got the recording time delay in computing the deep seafloor depth.All these tech-nologies obtained in the present study will provide some technical support for future acoustic subbottom detailed survey in deep sea.%深水浅部地层精细探测是深海地质勘探与资源开发的重要调查内容。与浅水海域声学地层剖面探测相比,深水地层剖面探测会遇到严重的能量衰减、大数据量长时间反射序列采样、纵向地层分辨率降低以及横向空间覆盖率偏稀等问题,为解决这些问题,国外仪器商采用了不同的方法。采取重采样减少数据量会严重影响纵向分辨率;采取 MultiPing 技术可以很好解决横向空间覆盖率问题,但多 Ping 接收采用海底追踪变深度范围采集会造成反射同相轴跳跃突变,或采用短时间间隔采集会造成回波数据无法准确计算海底深度。为了解决这些技术问题

  19. Nonadhesive acoustic membranes based on polyimide

    Directory of Open Access Journals (Sweden)

    Vorob'ev A.V.

    2014-02-01

    Full Text Available The paper presents a comparison of technical characteristics of acoustic membranes with an adhesive layer and nonadhesive membranes. The authors present the manufacturing technology for acoustic membranes based on aluminum-polyimide film dielectrics and analyze the advantages of such membranes in comparison to other sound emitters.

  20. Simulation and Experiment Research of Non-contact Micro-liquid Reagent Dispensing

    Directory of Open Access Journals (Sweden)

    Yao Yufeng

    2013-05-01

    Full Text Available With the development of biological analytical techniques and high throughput screening techniques, a large number of automated biological agents dispensing systems are widely used in the field of life science research. Non-contact dispensing method characterized by its small dispensing volume, high dispensing precision and quick service speed which satisfies the requirements of biological agent’s distribution, becomes the mainstream dispensing method used in reagent dispensing systems. However, the difficult control way, complex system of non-contact dispensing method and its vulnerable dispensing process, which can be easily affected by characteristics of the agent, have hindered the application and development of the method. In this study, simulation model of the separation process of micro scale biological reagent are constructed in order to solve the above problems. The prerequisites of the non-contact dispensing method, the relationship between dispensing volume and precision and characteristics of reagents, formation of system and control parameters are researched through theoretical analysis and numerical simulations. The experiment results are quite consistent with the simulation results; therefore it well verifies the reliability of the modeling and simulation method and also lays a firm theoretical foundation for the system design of non-contact micro-liquid reagent distribution and control optimization.

  1. Hydrogen Station Compression, Storage, and Dispensing Technical Status and Costs: Systems Integration

    Energy Technology Data Exchange (ETDEWEB)

    Parks, G.; Boyd, R.; Cornish, J.; Remick, R.

    2014-05-01

    At the request of the U.S. Department of Energy Fuel Cell Technologies Office (FCTO), the National Renewable Energy Laboratory commissioned an independent review of hydrogen compression, storage, and dispensing (CSD) for pipeline delivery of hydrogen and forecourt hydrogen production. The panel was asked to address the (1) cost calculation methodology, (2) current cost/technical status, (3) feasibility of achieving the FCTO's 2020 CSD levelized cost targets, and to (4) suggest research areas that will help the FCTO reach its targets. As the panel neared the completion of these tasks, it was also asked to evaluate CSD costs for the delivery of hydrogen by high-pressure tube trailer. This report details these findings.

  2. Acoustic Droplet Ejection Applications for High-Throughput Screening of Infectious Agents.

    Science.gov (United States)

    Rasmussen, Lynn; White, E Lucile; Bostwick, James R

    2016-02-01

    When acoustic droplet ejection technology was first introduced for high-throughput applications, it was used primarily for dispensing compounds dissolved in DMSO. The high precision and accuracy achieved for low-volume transfers in this application were noted by those working outside of the compound management area, and interest was generated in expanding the scope of the technology to include other liquid types. Later-generation instruments included calibrations for several aqueous buffers that were applicable to the life sciences. The High Throughput Screening Center at Southern Research has made use of this range of liquid calibrations for the Infectious Disease Program. The original calibration for DMSO has allowed the preparation of assay-ready plates that can be sent to remote locations. This process was used as part of the collaboration between Southern Research and Galveston National Laboratory, University of Texas Medical Branch, to develop high-throughput screening for biological safety level 4 containment and to provide compounds for two pilot screens that were run there with BSL-4-level pathogens. The aqueous calibrations have been instrumental in miniaturizing assays used for infectious disease, such as qPCR, tissue culture infectious dose 50, and bacterial motility, to make them compatible with HTS operations. PMID:26663786

  3. Overcoming barriers to the implementation of a pharmacy bar code scanning system for medication dispensing: a case study.

    Science.gov (United States)

    Nanji, Karen C; Cina, Jennifer; Patel, Nirali; Churchill, William; Gandhi, Tejal K; Poon, Eric G

    2009-01-01

    Technology has great potential to reduce medication errors in hospitals. This case report describes barriers to, and facilitators of, the implementation of a pharmacy bar code scanning system to reduce medication dispensing errors at a large academic medical center. Ten pharmacy staff were interviewed about their experiences during the implementation. Interview notes were iteratively reviewed to identify common themes. The authors identified three main barriers to pharmacy bar code scanning system implementation: process (training requirements and process flow issues), technology (hardware, software, and the role of vendors), and resistance (communication issues, changing roles, and negative perceptions about technology). The authors also identified strategies to overcome these barriers. Adequate training, continuous improvement, and adaptation of workflow to address one's own needs mitigated process barriers. Ongoing vendor involvement, acknowledgment of technology limitations, and attempts to address them were crucial in overcoming technology barriers. Staff resistance was addressed through clear communication, identifying champions, emphasizing new information provided by the system, and facilitating collaboration. PMID:19567797

  4. Study on Tracking and Positioning Technology of Mine Rising Trajectory by Underwater Acoustic Pulse Encoding%水雷上浮弹道水声脉冲编码跟踪定位技术研究

    Institute of Scientific and Technical Information of China (English)

    杜召平; 刘百峰

    2013-01-01

    According to the ranging and positioning principle of synchronized underwater acoustic pulse, the positioning technology by underwater multi-channel GPS sonar buoy array _mine-borne 3D segment is used to track and position the rising mines.Multi-frequency underwater acoustic pulse encoded technology is used to expand transmitting period for underwater acoustic pulse.The problems are solved that measurement period is fuzzy and measurement data size is not enough.The mine-borne 3D segment designed by perception of mine states and energy-saving technology has functions on conversion of operational states and transmitting underwater acoustic signals for a long time.The simulated model for the system tracking and positioning accuracy is set up with spherical intersection positioning solution.Influences on the system positioning accuracy are predicted for the system synchronized accuracy, time-delay detection accuracy of underwater acoustic signals, GPS positioning accuracy, hydrophone position accuracy and measurement accuracy of sound velocity.The grounds are provided for the technology feasibility and the development of correlated series of measurement and control equipment.%根据同步水声脉冲测距定位原理,利用水下多信道GPS声纳浮标阵-雷载3D段定位技术,对上浮水雷进行跟踪定位.利用多频水声脉冲编码技术扩展水声脉冲发射周期,解决了测量周期模糊与测量数据量匮乏的问题.利用水雷状态感知和节能技术设计的雷载3D,段具有工作状态转换和长时间水声信号发射功能.利用球面交汇定位解法建立了系统跟踪定位精度仿真模型,通过仿真预测出系统同步精度、水声信号时延检测精度、GPS定位精度、水听器位置精度和声速测量精度对系统定位精度的影响,为此项技术的可行性和相关系列测控装备的研制提供了依据.

  5. Acoustics, computers and measurements

    Science.gov (United States)

    Truchard, James J.

    2003-10-01

    The human ear has created a high standard for the requirements of acoustical measurements. The transient nature of most acoustical signals has limited the success of traditional volt meters. Professor Hixson's pioneering work in electroacoustical measurements at ARL and The University of Texas helped set the stage for modern computer-based measurements. The tremendous performance of modern PCs and extensive libraries of signal processing functions in virtual instrumentation application software has revolutionized the way acoustical measurements are made. Today's analog to digital converters have up to 24 bits of resolution with a dynamic range of over 120 dB and a single PC processor can process 112 channels of FFTs at 4 kHz in real time. Wavelet technology further extends the capabilities for analyzing transients. The tools available for measurements in speech, electroacoustics, noise, and vibration represent some of the most advanced measurement tools available. During the last 50 years, Professor Hixson has helped drive this revolution from simple oscilloscope measurements to the modern high performance computer-based measurements.

  6. Hand sanitizer-dispensing door handles increase hand hygiene compliance: a pilot study.

    Science.gov (United States)

    Babiarz, Lukasz S; Savoie, Brent; McGuire, Mark; McConnell, Lauren; Nagy, Paul

    2014-04-01

    Improving rates of hand hygiene compliance (HHC) has been shown to reduce nosocomial disease. We compared the HHC for a traditional wall-mounted unit and a novel sanitizer-dispensing door handle device in a hospital inpatient ultrasound area. HHC increased 24.5%-77.1% (P sanitizer-dispensing door handle, whereas it remained unchanged for the other rooms. Technical improvements like a sanitizer-dispensing door handle can improve hospital HHC. PMID:24679575

  7. Physician drug dispensing in Switzerland: association on health care expenditures and utilization

    OpenAIRE

    Trottmann, Maria; Frueh, Mathias; Telser, Harry; Reich, Oliver

    2016-01-01

    Background Several countries recently reassessed the roles of drug prescribing and dispensing, either by enlarging pharmacists’ rights to prescribe (e.g. the US and the United Kingdom) or by limiting physicians’ rights to dispense (e.g. Taiwan and South Korea). While integrating the two roles might increase supply and be convenient for patients, concern is that drug mark-ups incite providers to prescribe unnecessary drugs. We aimed to assess the association of physician dispensing (PD) in Swi...

  8. Regulations, Codes, and Standards (RCS) Template for California Hydrogen Dispensing Stations

    Energy Technology Data Exchange (ETDEWEB)

    Rivkin, C.; Blake, C.; Burgess, R.; Buttner, W.; Post, M.

    2012-11-01

    This report explains the Regulations, Codes, and Standards (RCS) requirements for hydrogen dispensing stations in the State of California. The reports shows the basic components of a hydrogen dispensing station in a simple schematic drawing; the permits and approvals that would typically be required for the construction and operation of a hydrogen dispensing station; and a basic permit that might be employed by an Authority Having Jurisdiction (AHJ).

  9. Acoustic Monitoring for Spaceflight Vehicle Applications Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR will develop and demonstrate acoustic sensor technology enabling real-time, remotely performed measuring and monitoring of sound pressure levels and noise...

  10. Guide to Permitting Hydrogen Motor Fuel Dispensing Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Rivkin, Carl [National Renewable Energy Lab. (NREL), Golden, CO (United States); Buttner, William [National Renewable Energy Lab. (NREL), Golden, CO (United States); Burgess, Robert [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-03-28

    The purpose of this guide is to assist project developers, permitting officials, code enforcement officials, and other parties involved in developing permit applications and approving the implementation of hydrogen motor fuel dispensing facilities. The guide facilitates the identification of the elements to be addressed in the permitting of a project as it progresses through the approval process; the specific requirements associated with those elements; and the applicable (or potentially applicable) codes and standards by which to determine whether the specific requirements have been met. The guide attempts to identify all applicable codes and standards relevant to the permitting requirements.

  11. LOCATING LEAKS WITH ACOUSTIC TECHNOLOGY

    Science.gov (United States)

    Many water distribution systems in this country are almost 100 years old. About 26 percent of piping in these systems is made of unlined cast iron or steel and is in poor condition. Many methods that locate leaks in these pipes are time-consuming, costly, disruptive to operations...

  12. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available Educational Video Home What is an AN What is an Acoustic Neuroma? Identifying an AN Symptoms Acoustic Neuroma Keywords Educational Video ... for pre- and post-treatment acoustic neuroma patients. Home What is an AN What is an Acoustic ...

  13. Acoustic cryocooler

    Science.gov (United States)

    Swift, Gregory W.; Martin, Richard A.; Radenbaugh, Ray

    1990-01-01

    An acoustic cryocooler with no moving parts is formed from a thermoacoustic driver (TAD) driving a pulse tube refrigerator (PTR) through a standing wave tube. Thermoacoustic elements in the TAD are spaced apart a distance effective to accommodate the increased thermal penetration length arising from the relatively low TAD operating frequency in the range of 15-60 Hz. At these low operating frequencies, a long tube is required to support the standing wave. The tube may be coiled to reduce the overall length of the cryocooler. One or two PTR's are located on the standing wave tube adjacent antinodes in the standing wave to be driven by the standing wave pressure oscillations. It is predicted that a heat input of 1000 W at 1000 K will maintian a cooling load of 5 W at 80 K.

  14. Use of acoustic vortices in acoustic levitation

    DEFF Research Database (Denmark)

    Cutanda Henriquez, Vicente; Santillan, Arturo Orozco; Juhl, Peter Møller

    2009-01-01

    Acoustic fields are known to exert forces on the surfaces of objects. These forces are noticeable if the sound pressure is sufficiently high. Two phenomena where acoustic forces are relevant are: i) acoustic levitation, where strong standing waves can hold small objects at certain positions......, counterbalancing their weight, and ii) acoustic vortices, spinning sound fields that can impinge angular momentum and cause rotation of objects. In this contribution, both force-creating sound fields are studied by means of numerical simulations. The Boundary Element Method is employed to this end. The simulation...... of acoustical vortices uses an efficient numerical implementation based on the superposition of two orthogonal sound fields with a delay of 90° between them. It is shown that acoustic levitation and the use of acoustic vortices can be combined to manipulate objects in an efficient and controlled manner without...

  15. The challenge of responsible dispensing: formal education versus professional practice

    Directory of Open Access Journals (Sweden)

    Nadine Judith Bezzegh

    2011-03-01

    Full Text Available The aim of the present study was to evaluate the education of Pharmaceutical Technicians for the activity of responsible dispensing. Based on a questionnaire with open and closed questions, the study sought to characterize the students, identify knowledge and attitudes regarding the Rational Use of Medications while addressing the limits and possibilities of professional and ethical dispensing in practice. In addition, a group dynamics session - focus group - was held as a forum for debate on responsible dispensing. The results showed that students tended to be mature, currently employed and were predominately women. Displaying adequate knowledge on Rational Use of Medications and of the corresponding legislation, the students reported difficulties exercising compatible practice. While the diagnosis pointed to the need for student preparation to enable ethical dispensing, the Focus Group highlighted the possibility for inclusion of a forum for reflection and debate on the ethics of dispensing as part of the Pharmaceutical Technician training.O presente trabalho tem como proposta avaliar a formação do Técnico em Farmácia para o exercício da dispensação responsável. A partir de um questionário com perguntas fechadas e abertas, o estudo envolveu a caracterização dos alunos, a identificação de conhecimentos e atitudes em relação ao Uso Racional dos Medicamentos com vistas ao delineamento dos limites e possibilidades do exercício profissional ético na dispensação. Além disso, foi realizada uma dinâmica grupal - grupo focal - com o objetivo de apreciar a constituição de um espaço de reflexão sobre a dispensação responsável. Os resultados evidenciaram um alunato de maior idade, inserido no mercado de trabalho e predominância de mulheres. Dispondo de conhecimento adequado sobre o Uso Racional dos Medicamentos e da legislação correspondente os alunos fazem referência às dificuldades no exercício de uma pr

  16. Acoustic multivariate condition monitoring - AMCM

    Energy Technology Data Exchange (ETDEWEB)

    Rosenhave, P.E. [Vestfold College, Maritime Dept., Toensberg (Norway)

    1997-12-31

    In Norway, Vestfold College, Maritime Department presents new opportunities for non-invasive, on- or off-line acoustic monitoring of rotating machinery such as off-shore pumps and diesel engines. New developments within acoustic sensor technology coupled with chemometric data analysis of complex signals now allow condition monitoring of hitherto unavailable flexibility and diagnostic specificity. Chemometrics paired with existing knowledge yields a new and powerful tool for condition monitoring. By the use of multivariate techniques and acoustics it is possible to quantify wear and tear as well as predict the performance of working components in complex machinery. This presentation describes the AMCM method and one result of a feasibility study conducted onboard the LPG/C `Norgas Mariner` owned by Norwegian Gas Carriers as (NGC), Oslo. (orig.) 6 refs.

  17. Acoustic dispersive prism

    OpenAIRE

    Hussein Esfahlani; Sami Karkar; Herve Lissek; Mosig, Juan R.

    2016-01-01

    The optical dispersive prism is a well-studied element, which allows separating white light into its constituent spectral colors, and stands in nature as water droplets. In analogy to this definition, the acoustic dispersive prism should be an acoustic device with capability of splitting a broadband acoustic wave into its constituent Fourier components. However, due to the acoustical nature of materials as well as the design and fabrication difficulties, there is neither any natural acoustic ...

  18. Device for manual aspiration and dispensing of radionuclide solutions in medicine

    International Nuclear Information System (INIS)

    This device for manual aspiration of dispensing of radionuclide solutions in medicine, particularly for transferring radionuclide solutions from closed bottles to syringes to be injected to patients or for subsequent dispensing into closed bottles, is safe and convenient to handle because any hand contact is avoided. (P.A.)

  19. Drug dispensing practices at pharmacies in Bengaluru: A cross-sectional study

    Science.gov (United States)

    Soumya, R.; Devarashetty, Vijayalakshmi; Jayanthi, C. R.; Sushma, M.

    2016-01-01

    Objectives: Pharmacists are one of the crucial focal points for health care in the community. They have tremendous outreach to the public as pharmacies are often the first-port-of-call. With the increase of ready-to-use drugs, the main health-related activity of a pharmacist today is to assure the quality of dispensing, a key element to promote rational medicine use. Materials and Methods: A cross-sectional study of 200 pharmacies, 100 each in various residential (R) and commercial (C) areas of Bengaluru, was conducted using a prevalidated questionnaire administered to the chief pharmacist or the person-in-charge by the investigators. Results: Dispensing without prescription at pharmacies was 45% of the total dispensing encounters and significantly higher (χ2 = 15.2, P educational campaigns are a prerequisite to improve dispenser's knowledge and dispensing practices.

  20. 30th International Acoustical Imaging Symposium

    CERN Document Server

    Jones, Joie; Lee, Hua

    2011-01-01

    The International Symposium on Acoustical Imaging is a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. This interdisciplinary Symposium has been taking place every two years since 1968. In the course of the years the proceedings volumes in the Acoustical Imaging Series have become a reference for cutting-edge research in the field. In 2009 the 30th International Symposium on Acoustical Imaging was held in Monterey, CA, USA, March 1-4. Offering both a broad perspective on the state-of-the-art as well as  in-depth research contributions by the specialists in the field, this Volume 30 in the Series contains an excellent collection of forty three papers presented in five major categories: Biomedical Imaging Acoustic Microscopy Non-Destructive Evaluation Systems Analysis Signal Analysis and Image Processing Audience Researchers in medical imaging and biomedical instrumentation experts.

  1. Influence of container structures and content solutions on dispensing time of ophthalmic solutions

    Directory of Open Access Journals (Sweden)

    Keiji Yoshikawa

    2010-05-01

    Full Text Available Keiji Yoshikawa1, Hiroshi Yamada21Yoshikawa Eye Clinic, Tokyo, Japan; 2Santen Pharmaceutical Co., Ltd., Osaka, JapanPurpose: To investigate the influence of container structures and content solutions on the time of dispensing from eye dropper bottles.Methods: Eye dropper bottle models, solution models (filtrate water/surfactant solution and a dispensing time measuring apparatus were prepared to measure the dispensing time.Results: With filtrate water and pressure thrust load of 0.3 MPa, the dispensing time significantly increased from 1.1 ± 0.5 seconds to 4.6 ± 1.1 seconds depending on the decrease of inner aperture diameters from 0.4 mm to 0.2 mm (P < 0.0001. When using the bottle models with inner aperture diameters of 0.4 mm or larger, the dispensing time became constant. The dispensing time using surfactant solution showed the same tendency as above. When pressure thrust load was large (0.07 MPa, the solution flew out continuously with inner aperture diameters of 0.4 mm or larger and the dispensing time could not be measured. The inner aperture diameter most strongly explained the variation of the dispensing time in both the content solutions in the multiple linear regression analysis (filtrate water: 46%, R2 = 0.462, surfactant solution: 56%, R2 = 0.563.Conclusions: Among content solutions and container structures, the dispensing time was mostly influenced by the diameter of the inner aperture of bottles.Keywords: dispensing time, model eye dropper bottle, model ophthalmic solution, nozzle internal space volume, nozzle inner aperture diameter

  2. Responsive acoustic surfaces

    DEFF Research Database (Denmark)

    Peters, Brady; Tamke, Martin; Nielsen, Stig Anton;

    2011-01-01

    Acoustic performance is defined by the parameter of reverberation time; however, this does not capture the acoustic experience in some types of open plan spaces. As many working and learning activities now take place in open plan spaces, it is important to be able to understand and design...... for the acoustic conditions of these spaces. This paper describes an experimental research project that studied the design processes necessary to design for sound. A responsive acoustic surface was designed, fabricated and tested. This acoustic surface was designed to create specific sonic effects. The design...... was simulated using custom integrated acoustic software and also using Odeon acoustic analysis software. The research demonstrates a method for designing space- and sound-defining surfaces, defines the concept of acoustic subspace, and suggests some new parameters for defining acoustic subspaces....

  3. Springer Handbook of Acoustics

    CERN Document Server

    Rossing, Thomas D

    2007-01-01

    Acoustics, the science of sound, has developed into a broad interdisciplinary field encompassing the academic disciplines of physics, engineering, psychology, speech, audiology, music, architecture, physiology, neuroscience, and others. The Springer Handbook of Acoustics is an unparalleled modern handbook reflecting this richly interdisciplinary nature edited by one of the acknowledged masters in the field, Thomas Rossing. Researchers and students benefit from the comprehensive contents spanning: animal acoustics including infrasound and ultrasound, environmental noise control, music and human speech and singing, physiological and psychological acoustics, architectural acoustics, physical and engineering acoustics, signal processing, medical acoustics, and ocean acoustics. This handbook reviews the most important areas of acoustics, with emphasis on current research. The authors of the various chapters are all experts in their fields. Each chapter is richly illustrated with figures and tables. The latest rese...

  4. Acoustic Spatiality

    Directory of Open Access Journals (Sweden)

    Brandon LaBelle

    2012-06-01

    Full Text Available Experiences of listening can be appreciated as intensely relational, bringing us into contact with surrounding events, bodies and things. Given that sound propagates and expands outwardly, as a set of oscillations from a particular source, listening carries with it a sensual intensity, whereby auditory phenomena deliver intrusive and disruptive as well as soothing and assuring experiences. The physicality characteristic of sound suggests a deeply impressionistic, locational "knowledge structure" – that is, the ways in which listening affords processes of exchange, of being in the world, and from which we extend ourselves. Sound, as physical energy reflecting and absorbing into the materiality around us, and even one's self, provides a rich platform for understanding place and emplacement. Sound is always already a trace of location.Such features of auditory experience give suggestion for what I may call an acoustical paradigm – how sound sets in motion not only the material world but also the flows of the imagination, lending to forces of signification and social structure, and figuring us in relation to each other. The relationality of sound brings us into a steady web of interferences, each of which announces the promise or problematic of being somewhere.

  5. Acoustic Neurinomas

    Directory of Open Access Journals (Sweden)

    Mohammad Faraji Rad

    2011-01-01

    Full Text Available Acoustic neuromas (AN are schwann cell-derived tumors that commonly arise from the vestibular portion of the eighth cranial nerve also known as vestibular schwannoma(VS causes unilateral hearing loss, tinnitus, vertigo and unsteadiness. In many cases, the tumor size may remain unchanged for many years following diagnosis, which is typically made by MRI. In the majority of cases the tumor is small, leaving the clinician and patient with the options of either serial scanning or active treatment by gamma knife radiosurgery (GKR or microneurosurgery. Despite the vast number of published treatment reports, comparative studies are few. The predominant clinical endpoints of AN treatment include tumor control, facial nerve function and hearing preservation. Less focus has been put on symptom relief and health-related quality of life (QOL. It is uncertain if treating a small tumor leaves the patient with a better chance of obtaining relief from future hearing loss, vertigo or tinnitus than by observing it without treatment.   In this paper we review the literature for the natural course, the treatment alternatives and the results of AN. Finally, we present our experience with a management strategy applied for more than 30 years.

  6. Acoustic Mechanical Feedthroughs

    Science.gov (United States)

    Sherrit, Stewart; Walkemeyer, Phillip; Bao, Xiaoqi; Bar-Cohen, Yoseph; Badescu, Mircea

    2013-01-01

    Electromagnetic motors can have problems when operating in extreme environments. In addition, if one needs to do mechanical work outside a structure, electrical feedthroughs are required to transport the electric power to drive the motor. In this paper, we present designs for driving rotary and linear motors by pumping stress waves across a structure or barrier. We accomplish this by designing a piezoelectric actuator on one side of the structure and a resonance structure that is matched to the piezoelectric resonance of the actuator on the other side. Typically, piezoelectric motors can be designed with high torques and lower speeds without the need for gears. One can also use other actuation materials such as electrostrictive, or magnetostrictive materials in a benign environment and transmit the power in acoustic form as a stress wave and actuate mechanisms that are external to the benign environment. This technology removes the need to perforate a structure and allows work to be done directly on the other side of a structure without the use of electrical feedthroughs, which can weaken the structure, pipe, or vessel. Acoustic energy is pumped as a stress wave at a set frequency or range of frequencies to produce rotary or linear motion in a structure. This method of transferring useful mechanical work across solid barriers by pumping acoustic energy through a resonant structure features the ability to transfer work (rotary or linear motion) across pressure or thermal barriers, or in a sterile environment, without generating contaminants. Reflectors in the wall of barriers can be designed to enhance the efficiency of the energy/power transmission. The method features the ability to produce a bi-directional driving mechanism using higher-mode resonances. There are a variety of applications where the presence of a motor is complicated by thermal or chemical environments that would be hostile to the motor components and reduce life and, in some instances, not be

  7. Analysis of fluoride concentration in solutions prepared at dispensing pharmacies

    Directory of Open Access Journals (Sweden)

    Eduardo Pizzatto

    2011-07-01

    Full Text Available Introduction: Fluoride plays an important role in oral health promotion and is considered important in dental caries prevention both in children and adults. Fluoride is widely used at high-risk conditions of caries, when the use of fluoride-containing mouthwashes is recommended, considering that fluoride itself reduces the risk of dental caries. Objective: To evaluate the fluoride concentration in solutions prepared at different dispensing pharmacies in the city of Curitiba – PR, Brazil. Material and methods: The analysis of fluoride concentration was preformed through Ion Chromatography method (DIONEX. Results: The results obtained through this analysis showed that all solutions presented fluoride concentration above that required in the dentist’s prescription, varying between 5.48% and 24.02% more fluoride, at absolute concentration. Conclusion: This finding highlights the increasing risk of fluoride acute intoxication in cases of accidental ingestion of the solution.

  8. Sprayed, not stirred. A self-development of the company Sauter enables the dispension with agitators; Versprueht, nicht geruehrt. Eine Eigenentwicklung der Firma Sauter ermoeglicht es, auf Ruehrwerke zu verzichten

    Energy Technology Data Exchange (ETDEWEB)

    Waid, Johanna

    2012-07-01

    'Simplicity is better' - This might be the motto of the company Sauter Biogas GmbH (Klipphausen, Federal Republic of Germany). The biogas plants of this company were developed from own practical experience and need any solids dispenser. A special mixing technology replaces the otherwise common agitators.

  9. Visualization of Surface Acoustic Waves in Thin Liquid Films.

    Science.gov (United States)

    Rambach, R W; Taiber, J; Scheck, C M L; Meyer, C; Reboud, J; Cooper, J M; Franke, T

    2016-01-01

    We demonstrate that the propagation path of a surface acoustic wave (SAW), excited with an interdigitated transducer (IDT), can be visualized using a thin liquid film dispensed onto a lithium niobate (LiNbO3) substrate. The practical advantages of this visualization method are its rapid and simple implementation, with many potential applications including in characterising acoustic pumping within microfluidic channels. It also enables low-cost characterisation of IDT designs thereby allowing the determination of anisotropy and orientation of the piezoelectric substrate without the requirement for sophisticated and expensive equipment. Here, we show that the optical visibility of the sound path critically depends on the physical properties of the liquid film and identify heptane and methanol as most contrast rich solvents for visualization of SAW. We also provide a detailed theoretical description of this effect. PMID:26917490

  10. Acoustic source for generating an acoustic beam

    Energy Technology Data Exchange (ETDEWEB)

    Vu, Cung Khac; Sinha, Dipen N.; Pantea, Cristian

    2016-05-31

    An acoustic source for generating an acoustic beam includes a housing; a plurality of spaced apart piezo-electric layers disposed within the housing; and a non-linear medium filling between the plurality of layers. Each of the plurality of piezoelectric layers is configured to generate an acoustic wave. The non-linear medium and the plurality of piezo-electric material layers have a matching impedance so as to enhance a transmission of the acoustic wave generated by each of plurality of layers through the remaining plurality of layers.

  11. Canonical Acoustics and Its Application to Surface Acoustic Wave on Acoustic Metamaterials

    Science.gov (United States)

    Shen, Jian Qi

    2016-08-01

    In a conventional formalism of acoustics, acoustic pressure p and velocity field u are used for characterizing acoustic waves propagating inside elastic/acoustic materials. We shall treat some fundamental problems relevant to acoustic wave propagation alternatively by using canonical acoustics (a more concise and compact formalism of acoustic dynamics), in which an acoustic scalar potential and an acoustic vector potential (Φ ,V), instead of the conventional acoustic field quantities such as acoustic pressure and velocity field (p,u) for characterizing acoustic waves, have been defined as the fundamental variables. The canonical formalism of the acoustic energy-momentum tensor is derived in terms of the acoustic potentials. Both the acoustic Hamiltonian density and the acoustic Lagrangian density have been defined, and based on this formulation, the acoustic wave quantization in a fluid is also developed. Such a formalism of acoustic potentials is employed to the problem of negative-mass-density assisted surface acoustic wave that is a highly localized surface bound state (an eigenstate of the acoustic wave equations). Since such a surface acoustic wave can be strongly confined to an interface between an acoustic metamaterial (e.g., fluid-solid composite structures with a negative dynamical mass density) and an ordinary material (with a positive mass density), it will give rise to an effect of acoustic field enhancement on the acoustic interface, and would have potential applications in acoustic device design for acoustic wave control.

  12. A review of fishing technology by acoustic attraction%声诱捕捞技术的研究现状和应用前景

    Institute of Scientific and Technical Information of China (English)

    张国胜; 杨超杰; 邢彬彬

    2012-01-01

    The concept and research status of fishing by acoustic attraction are introduced in world. Then the role of the fishing by acoustic attraction in protection of fishery resources and environment is considered based on present problems with fisheries. The application of the fishing by acoustic attraction is discussed and establishment of freshwater ranching fisheries is suggested in China.%介绍了声诱捕捞技术的概念及国内外声诱捕捞技术的研究现状;针对目前渔业资源所面临的问题,分析和探讨了声诱捕捞技术在保护渔业资源和渔业环境方面所起的作用;阐述了声诱捕捞技术的应用前景,并提出了结合声诱捕捞技术在中国建设淡水牧场的新构想.

  13. Reductions in finger doses for radiopharmaceutical dispensing afforded by a syringe shield and an automatic dose dispenser

    International Nuclear Information System (INIS)

    The Gamma Extremity Monitoring System (GEMS) uses a small semiconductor probe from which a continuous readout of dose-rate is obtained (Montgomery et al, 1997). It-is a small, lightweight system that is simple to use and can provide rapid feedback. With GEMS doses received from individual operations and actions within a particular procedure can be recorded so that the pattern of dose accumulation can be analysed enabling techniques to be optimised for dose reduction, the whole process taking a relatively short period of time. The present study reports how a GEMS has been utilised to compare the radiation dose reduction afforded by a syringe and an automatic dose dispenser and looks at the pattern of dose accumulation during each procedure. (Author)

  14. Evaluation of a new photoresist dispense system to detect coating variation

    Science.gov (United States)

    Gapin, Florent; Le-Peutrec, Bernard; Stock, Laurent; Hanotte, Marc

    2009-03-01

    A minimal change of dispensed volume will have a severe impact on the film thickness uniformity and in the worst case there might be some lack of resist on the wafer. Therefore it is essential to set-up the photoresist dispense accurately to avoid any dispense variation. In addition, it is important to monitor the dispense conditions real-time to detect problems which may have a direct negative impact on process yield. This paper presents the evaluation of the IntelliGen® Mini dispense system which is manufactured by Entegris, Inc. This new system is able to detect variations like bubbles in the dispense line, changes to the stop suckback valve, and changes in viscosity1. After an explanation of the pump characteristics and the potential root causes of dispense variation and their consequences, the evaluation done in Altis Semiconductor will be presented. The study has been made utilizing different photo-chemicals, including low and mid-range viscosity photo- resists and anti-reflective coatings. The capability of this new product to detect any perturbation of coating will be demonstrated. Then standard tests like coating repeatability, defect density CD uniformity and finally wafer yield inspection will be performed to prove efficiency of the system in a production mode.

  15. Bacterial hand contamination and transfer after use of contaminated bulk-soap-refillable dispensers.

    Science.gov (United States)

    Zapka, Carrie A; Campbell, Esther J; Maxwell, Sheri L; Gerba, Charles P; Dolan, Michael J; Arbogast, James W; Macinga, David R

    2011-05-01

    Bulk-soap-refillable dispensers are prone to extrinsic bacterial contamination, and recent studies demonstrated that approximately one in four dispensers in public restrooms are contaminated. The purpose of this study was to quantify bacterial hand contamination and transfer after use of contaminated soap under controlled laboratory and in-use conditions in a community setting. Under laboratory conditions using liquid soap experimentally contaminated with 7.51 log(10) CFU/ml of Serratia marcescens, an average of 5.28 log(10) CFU remained on each hand after washing, and 2.23 log(10) CFU was transferred to an agar surface. In an elementary-school-based field study, Gram-negative bacteria on the hands of students and staff increased by 1.42 log(10) CFU per hand (26-fold) after washing with soap from contaminated bulk-soap-refillable dispensers. In contrast, washing with soap from dispensers with sealed refills significantly reduced bacteria on hands by 0.30 log(10) CFU per hand (2-fold). Additionally, the mean number of Gram-negative bacteria transferred to surfaces after washing with soap from dispensers with sealed-soap refills (0.06 log(10) CFU) was significantly lower than the mean number after washing with contaminated bulk-soap-refillable dispensers (0.74 log(10) CFU; P soap (P soap from bulk-soap-refillable dispensers can increase the number of opportunistic pathogens on the hands and may play a role in the transmission of bacteria in public settings.

  16. The accuracy and timeliness of neuraminidase inhibitor dispensing data for predicting laboratory-confirmed influenza.

    Science.gov (United States)

    Papenburg, J; Charland, K M; DE Serres, G; Buckeridge, D L

    2016-06-01

    Neuraminidase inhibitor (NI) dispensing has emerged as a possible automated data source for influenza surveillance. We aimed to evaluate its timeliness, correlation, and predictive accuracy in relation to influenza activity in Quebec, Canada, 2010-2013. Our secondary objective was to use the same metrics to compare NI dispensing to visits for influenza-like illness (ILI) in emergency departments (EDs). Provincial weekly counts of positive influenza laboratory tests were used as a reference measure for the level of influenza circulation. We applied ARIMA models to account for serial correlation. We computed cross-correlations to measure the strengths of association and lead-lag relationships between NI dispensing, ILI ED visits, and our reference indicator. Finally, using an ARIMA model, we evaluated the ability of NI dispensing and ILI ED visits to predict laboratory-confirmed influenza. NI dispensing was significantly correlated (R = 0·68) with influenza activity with no lag. The maximal correlation of ILI ED visits was not as strong (R = 0·50). Both NI dispensing and ILI ED visits were significant predictors of laboratory-confirmed influenza in a multivariable model; predictive potential was greatest when NI counts were lagged to precede laboratory surveillance by 2 weeks. We conclude that NI dispensing data provides timely and valuable information for influenza surveillance. PMID:26611607

  17. High-Precision Dispensing of Nanoliter Biofluids on Glass Pedestal Arrays for Ultrasensitive Biomolecule Detection.

    Science.gov (United States)

    Chen, Xiaoxiao; Liu, Yang; Xu, QianFeng; Zhu, Jing; Poget, Sébastien F; Lyons, Alan M

    2016-05-01

    Precise dispensing of nanoliter droplets is necessary for the development of sensitive and accurate assays, especially when the availability of the source solution is limited. Conventional approaches are limited by imprecise positioning, large shear forces, surface tension effects, and high costs. To address the need for precise and economical dispensing of nanoliter volumes, we developed a new approach where the dispensed volume is dependent on the size and shape of defined surface features, thus freeing the dispensing process from pumps and fine-gauge needles requiring accurate positioning. The surface we fabricated, called a nanoliter droplet virtual well microplate (nVWP), achieves high-precision dispensing (better than ±0.5 nL or ±1.6% at 32 nL) of 20-40 nL droplets using a small source drop (3-10 μL) on isolated hydrophilic glass pedestals (500 μm on a side) bonded to arrays of polydimethylsiloxane conical posts. The sharp 90° edge of the glass pedestal pins the solid-liquid-vapor triple contact line (TCL), averting the wetting of the glass sidewalls while the fluid is prevented from receding from the edge. This edge creates a sufficiently large energy barrier such that microliter water droplets can be poised on the glass pedestals, exhibiting contact angles greater >150°. This approach relieves the stringent mechanical alignment tolerances required for conventional dispensing techniques, shifting the control of dispensed volume to the area circumscribed by the glass edge. The effects of glass surface chemistry and dispense velocity on droplet volume were studied using optical microscopy and high-speed video. Functionalization of the glass pedestal surface enabled the selective adsorption of specific peptides and proteins from synthetic and natural biomolecule mixtures, such as venom. We further demonstrate how the nVWP dispensing platform can be used for a variety of assays, including sensitive detection of proteins and peptides by fluorescence

  18. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... ANA Annual Reports Acoustic Neuroma Legacy Society Programs & Services Join/Renew Ways to Give ANA Discussion Forum ... ANA Annual Reports Acoustic Neuroma Legacy Society Programs & Services Search ANAUSA.org Connect with us! Educational Video ...

  19. Cystic acoustic neuromas

    OpenAIRE

    Chitkara, Naveen; Chanda, Rakesh; Yadav, S. P. S.; N.K. Sharma

    2002-01-01

    Predominantly cystic acoustic neuromas are rare and they usually present with clinical and radiological features different from their more common solid counterparts. Two cases of cystic acoustic neuromas are reported here.

  20. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... is ANA? Mission Statement Board of Directors ANA Staff Medical Advisory Board News ANA Annual Reports Acoustic ... is ANA? Mission Statement Board of Directors ANA Staff Medical Advisory Board News ANA Annual Reports Acoustic ...

  1. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Watch and Wait Radiation Microsurgery Acoustic Neuroma Decision Tree Questions for Your Physician Questions to Ask Yourself ... Watch and Wait Radiation Microsurgery Acoustic Neuroma Decision Tree Questions for Your Physician Questions to Ask Yourself ...

  2. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Resources Patient Surveys Related Links Clinical Trials.gov Health Care Insurance Toolkit Additional Resources ANA Public Webinars © 2016 Acoustic Neuroma Association Acoustic Neuroma Association ® • ...

  3. Acoustic cavitation movies

    Science.gov (United States)

    Crum, Lawrence A.

    2003-04-01

    Acoustic cavitation is a phenomenon that occurs on microsecond time scales and micron length scales, yet, it has many macroscopic manifestations. Accordingly, it is often difficult, at least for the author, to form realistic physical descriptions of the specific mechanisms through which it expresses itself in our macroscopic world. For example, there are still many who believe that cavitation erosion is due to the shock wave that is emitted by bubble implosion, rather than the liquid jet created on asymmetric collapse...and they may be right. Over the years, the author has accumulated a number of movies and high-speed photographs of cavitation activity, which he uses to form his own visual references. In the time allotted, he will show a number of these movies and photographs and discuss their relevance to existing technological problems. A limited number of CDs containing the presented materials will be available to interested individuals. [Work supported in part by the NIH, USAMRMC, and the ONR.

  4. Acoustic Design of Super-light Structures

    DEFF Research Database (Denmark)

    Christensen, Jacob Ellehauge; Hertz, Kristian Dahl; Brunskog, Jonas;

    aggregate (leca) along with a newly developed technology called pearl-chain reinforcement, which is a system for post-tensioning. Here, it is shown how to combine these technologies within a precast super-light slab element, while honoring the requirements of a holistic design. Acoustic experiments...

  5. Tutorial on architectural acoustics

    Science.gov (United States)

    Shaw, Neil; Talaske, Rick; Bistafa, Sylvio

    2002-11-01

    This tutorial is intended to provide an overview of current knowledge and practice in architectural acoustics. Topics covered will include basic concepts and history, acoustics of small rooms (small rooms for speech such as classrooms and meeting rooms, music studios, small critical listening spaces such as home theatres) and the acoustics of large rooms (larger assembly halls, auditoria, and performance halls).

  6. The impact of an automated dose-dispensing scheme on user compliance, medication understanding, and medication stockpiles

    DEFF Research Database (Denmark)

    Larsen, Anna Bira; Haugbølle, Lotte Stig

    2007-01-01

    BACKGROUND: It has been assumed that a new health technology, automated dose-dispensing (ADD), would result in benefits for medication users, including increased compliance, enhanced medication understanding, and improved safety. However, it was legislators and health professionals who pinpointed...... the more frequent type of behavior. After switching to ADD, most users experienced no change in understanding of their medications. ADD did not lead to automatic removal of old medications in users' homes; in fact for some users, ADD led to even larger medication stockpiles. Overall, reports from patients...... understanding, nor does it automatically eliminate stockpiles of old medication in users' homes. The gap between the perspectives of users and health professionals makes a compelling case for considering users' voices in the development and implementation of future health technologies....

  7. Efficiency potential of hot-drink dispensing machines in commercial catering; Effizienzpotenzial bei Heissgetraenkeautomaten in der Betriebsverpflegung

    Energy Technology Data Exchange (ETDEWEB)

    Grieder, T.; Huser, A. [Encontrol GmbH, Niederrohrdorf (Switzerland); Schmitz, R. [Electrosuisse, Fehraltorf (Switzerland)

    2003-07-01

    This final report for the Swiss Federal Office of Energy (SFOE) discusses the findings of a project that looked into the energy consumption of automatic hot-drink dispensing machines. The report presents the results of a survey made in Switzerland together with various manufacturers and operators of such machines that are used in the company refreshments sector. The survey provides important information on the current market situation, markets and market shares of individual operating companies as well as on machine technology and energy consumption. Also, obstacles to the improvement of energy efficiency in this area are looked at. Important savings that can be made in the operation of such machines are quoted. The report recommends that the results of a parallel survey of domestic coffee-making machines be taken note of and that effort should rather be concentrated in this area, where energy consumption at the national level is quoted as being around twice as high as for the commercial automatic hot-drink dispensing machines.

  8. Acoustic counter-sniper system

    Science.gov (United States)

    Duckworth, Gregory L.; Gilbert, Douglas C.; Barger, James E.

    1997-02-01

    BBN has developed, tested, and fielded pre-production versions of a versatile acoustics-based counter-sniper system. This system was developed by BBN for the DARPA Tactical Technology Office to provide a low cost and accurate sniper detection and localization system. The system uses observations of the shock wave from supersonic bullets to estimate the bullet trajectory, Mach number, and caliber. If muzzle blast observations are also available from unsilenced weapons, the exact sniper location along the trajectory is also estimated. A newly developed and very accurate model of the bullet ballistics and acoustic radiation is used which includes bullet deceleration. This allows the use of very flexible acoustic sensor types and placements, since the system can model the bullet's flight, and hence the acoustic observations, over a wide area very accurately. System sensor configurations can be as simple as two small four element tetrahedral microphone arrays on either side of the area to be protected, or six omnidirectional microphones spread over the area to be monitored. Increased performance can be obtained by expanding the sensor field in size or density, and the system software is easily reconfigured to accommodate this at deployment time. Sensor nodes can be added using wireless network telemetry or hardwired cables to the command node processing and display computer. The system has been field tested in three government sponsored tests in both rural and simulated urban environments at the Camp Pendleton MOUT facility. Performance was characterized during these tests for various shot geometries and bullet speeds and calibers.

  9. Cycle Shift Spread Spectrum Technology in Underwater Acoustic Communication%循环移位扩频水声通信技术研究磁

    Institute of Scientific and Technical Information of China (English)

    王喜龙; 张琳琳; 郭小宇

    2014-01-01

    Direct sequence spread spectrum communication system can work reliably in low SNR conditions ,and has great ability of anti multipath and anti -jamming because of its excellent related performance .This is extremely valuable for information transmission without error in underwater acoustic communication .However ,the communication rate of routine direct sequence spread spectrum underwater acoustic communication system is very low ,according to this characteristic ,this article studies the mode of cycle shift spread spectrum underwater acoustic communication ,and it increases communication rate of direct sequence spread spectrum communication system in the proposition of to promise a certain anti-interference abil-ity .%直接序列扩频通信系统因为其优良的相关性能,能够在较低的信噪比条件下进行可靠地工作,而拥有良好的抗多径和抗干扰的能力。这对于水声通信信息的无误码传输都是极为可贵的。可是,常规的直接序列扩频水声通信系统的通信速率很低,针对这一特点,论文研究了循环移位扩频水声通信方式,它在保证一定抗干扰能力的前提下成倍数提高直接序列扩频通信系统的通信速率。

  10. Parenteral medication prescriptions, dispensing and administration habits in Mongolia.

    Directory of Open Access Journals (Sweden)

    Gereltuya Dorj

    Full Text Available High levels of injection prescribing were reported in Mongolia. Understanding the factors influencing the injection prescribing is essential to reduce their inappropriate use. The study evaluated the views, experiences and attitudes of community members associated with the prescribing of injections in Mongolia. A structured questionnaire focusing on respondents' characteristics, experiences and views about injections was developed and administered face-to-face to community members in Ulaanbaatar, Mongolia. Standard descriptive statistics were used to summarize demographic data and responses to the questionnaires. Dependent variables were compared using Kruskal-Wallis Tests for independence. Statistical analyses were performed using SPSS Version 21.0. Six hundred participants were approached and the response rate was 79% (n = 474. Almost half of the respondents were aged between 31 and 50 (n = 228, 48.1% and 40.9% of respondents were male (n = 194. Most respondents were from Ulaanbaatar city (n = 407, 85.7%. All respondents had received injections in the past and 268 (56.5% had received injection in the past year. The most common reason for having an injection in the past year was reported as treatment of a disease (n = 163, 60.8%, or for administration of vitamins (n = 70, 26.1%. Injections were prescribed by a doctor (n = 353, 74.9%, dispensed by a pharmacist (n = 283, 59.7% and administered by a nurse (n = 277, 54.9%. Only 16% of all respondents had the expectation of receiving injections when they visited a doctor (n = 77. An important perception regarding injections was that they hastened the recovery process (n = 269, 56.8%. When asked their opinion about therapeutic injections, 40% of all respondents agreed that injections were a better medicine (n = 190 than oral medications, with older respondents strongly agreeing (p<0.001. Based on this total sample, approximately 1891 injections per 1000 patients were administered. The excessive

  11. Towards more reliable automated multi-dose dispensing: retrospective follow-up study on medication dose errors and product defects.

    Science.gov (United States)

    Palttala, Iida; Heinämäki, Jyrki; Honkanen, Outi; Suominen, Risto; Antikainen, Osmo; Hirvonen, Jouni; Yliruusi, Jouko

    2013-03-01

    To date, little is known on applicability of different types of pharmaceutical dosage forms in an automated high-speed multi-dose dispensing process. The purpose of the present study was to identify and further investigate various process-induced and/or product-related limitations associated with multi-dose dispensing process. The rates of product defects and dose dispensing errors in automated multi-dose dispensing were retrospectively investigated during a 6-months follow-up period. The study was based on the analysis of process data of totally nine automated high-speed multi-dose dispensing systems. Special attention was paid to the dependence of multi-dose dispensing errors/product defects and pharmaceutical tablet properties (such as shape, dimensions, weight, scored lines, coatings, etc.) to profile the most suitable forms of tablets for automated dose dispensing systems. The relationship between the risk of errors in dose dispensing and tablet characteristics were visualized by creating a principal component analysis (PCA) model for the outcome of dispensed tablets. The two most common process-induced failures identified in the multi-dose dispensing are predisposal of tablet defects and unexpected product transitions in the medication cassette (dose dispensing error). The tablet defects are product-dependent failures, while the tablet transitions are dependent on automated multi-dose dispensing systems used. The occurrence of tablet defects is approximately twice as common as tablet transitions. Optimal tablet preparation for the high-speed multi-dose dispensing would be a round-shaped, relatively small/middle-sized, film-coated tablet without any scored line. Commercial tablet products can be profiled and classified based on their suitability to a high-speed multi-dose dispensing process. PMID:22458299

  12. Acoustic elliptical cylindrical cloaks

    Institute of Scientific and Technical Information of China (English)

    Ma Hua; Qu Shao-Bo; Xu Zhuo; Wang Jia-Fu

    2009-01-01

    By making a comparison between the acoustic equations and the 2-dimensional (2D) Maxwell equations, we obtain the material parameter equations (MPE) for acoustic elliptical cylindrical cloaks. Both the theoretical results and the numerical results indicate that an elliptical cylindrical cloak can realize perfect acoustic invisibility when the spatial distributions of mass density and bulk modulus are exactly configured according to the proposed equations. The present work is the meaningful exploration of designing acoustic cloaks that are neither sphere nor circular cylinder in shape, and opens up possibilities for making complex and multiplex acoustic cloaks with simple models such as spheres, circular or elliptic cylinders.

  13. 基于声学参量阵的次声波定向仿真技术研究%Research on the Infrasound Directed Simulation Technology Based on Acoustic Parametric Arrays

    Institute of Scientific and Technical Information of China (English)

    张娜; 乔卫东

    2012-01-01

    The paper focus on the generation and orientation of the infrasound wave. By using the DDS technology, the different frequencies of Infrasoundwave is generated through the electro-acoustic conver-sion method. The orientation of infrasound wave has been formed by the way of acoustic parametric arrays which take the advantage of two ultrasound superposition and modulation. The sidelobe can be effectively suppressd and the infrasound wave can be centralized in the axial direction by the method so that trans-mission and orientation of the infrasound wave can be resolved. The feasibility of this method can be veri-fied by the simulation experiment.%针对次声波生成及定向技术展开研究.采用DDS技术通过电声转换实现了不同频率次声波的生成;应用声学参量阵,以两路超声波通过叠加,实现以超声波载波调制生成次生波.该方法可有效抑制旁瓣,使次声波主要集中在主轴方向,解决了次声波的定向传播问题,并通过仿真实验验证了该方法的可行性.

  14. APPLICATION OF THE INSTANT HOT WATER DISPENSER INTEGRATED INTO THE INTERNAL WATER SUPPLY SYSTEM OF RESIDENTIAL BUILDINGSAS AMETHOD OF SAVING POWER AND OTHER RESOURCES

    OpenAIRE

    Orlov Evgeniy Vladimirovich

    2012-01-01

    The author compares the instant water boiling technology and the use of electric teapots in the article. Strengths and weaknesses of the instant water boiling technology and its integration into the internal water supply system are also demonstrated. Aqua Hot 98 instant hot water dispenser is capable of heating up to 60 cups in an hour, while consuming 20 % of the electric power needed to boil the water on a stove or in an electric tea pot. Besides, the water is ready for consumption at a...

  15. A simple low-cost of liquid I-131 dispenser for routine radiopharmaceutical dispensing at nuclear medicine department, Institut Kanser Negara

    Energy Technology Data Exchange (ETDEWEB)

    Said, M. A.; Suhaimi, N. E. F. [Fakulti Sains dan Teknologi, Universiti Kebangsaan Malaysia, 43600 UKM, Bangi Selangor (Malaysia); Ashhar, Z. N., E-mail: aminhpj@gmail.com [Institut Kanser Negara, No 4, Jalan P7, Presint 7, 62250 Putrajaya (Malaysia); Zainon, R. [Advanced Medical & Dental Institute, Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Pulau Pinang (Malaysia)

    2016-01-22

    In routine radiopharmaceutical Iodine-131 ({sup 131}I) dispensing, the amount of radiation dose received by the personnel depends on the distance between the personnel and the source, the time spent manipulating the source and the amount of shielding used to reduce the dose rate from the source. The novel iRAD-I131 dispenser using recycle {sup 131}I liquid lead pot will lead into low cost production, less maintenance and low dose received by the personnel that prepared the {sup 131}I. The new fabricated of low cost {sup 131}I dispenser was tested and the dose received by personnel were evaluated. The body of lead material is made from 2.5 cm lead shielded coated with epoxy paint to absorb the radiation dose up to 7.4 GBq of {sup 131} I. The lead pot was supported with two stainless steel rod. The Optically Stimulated Luminescence (OSL) nanodot was used in this study to measure the dose rate at both extremities for every personnel who prepared the {sup 131}I. Each OSL nanodot was attached at the fingertip. Three different personnel (experienced between one to ten years above in preparing the radiopharmaceuticals) were participated in this study. The average equivalent dose at right and left hand were 122.694 ± 121.637 µSv/GBq and 77.281 ± 62.146 µSv/GBq respectively. This study found that the dose exposure received using iRAD-I131 was less up to seven times compared to the conventional method. The comparison of experimental data using iRAD-I131 and established radiopharmaceutical dispenser was also discussed. The innovation of {sup 131}I dispenser is highly recommended in a small radiopharmaceutical facility with limited budget. The novel iRAD-I131 enables implementation of higher output liquid dispensing with low radiation dose to the personnel.

  16. Separation of prescribing and dispensing in Malaysia: a summary of arguments.

    Science.gov (United States)

    Shafie, Asrul Akmal; Hassali, Mohamed Azmi; Azhar, Saira; See, Ooi Guat

    2012-01-01

    The role of pharmacists has transformed significantly because of changes in pharmacists' training and population health demands. Within this context, community pharmacists are recognized as important health personnel for the provision of extended health services. Similarly, in Malaysia, the need to transform community pharmacy practice has been discussed by all interested parties; however, the transition has been slow due in part to the nonexistence of a dispensing separation policy between pharmacists and medical doctors in private community practices. For decades, medical doctors in private community practices have had the right to prescribe and dispense, thus diluting the role of community pharmacists because of overlapping roles. This article explores dispensing separation in Malaysia and, by taking into account the needs of health professionals and health care consumers, suggests a mechanism for how dispensing separation practice can be implemented. PMID:21824823

  17. Balance Transmission Mechanism in Underwater Acoustic Sensor Networks

    OpenAIRE

    Jiabao Cao; Jinfeng Dou; Shunle Dong

    2015-01-01

    With the rapid development of underwater acoustic modem technology, underwater acoustic sensor networks (UWASNs) have more applications in long-term monitoring of the deployment area. In the underwater environment, the sensors are costly with limited energy. And acoustic communication medium poses new challenges, including high path loss, low bandwidth, and high energy consumption. Therefore, designing transmission mechanism to decrease energy consumption and to optimize the lifetime of UWASN...

  18. ACOUSTICAL STANDARDS NEWS.

    Science.gov (United States)

    Stremmel, Neil; Struck, Christopher J

    2016-07-01

    American National Standards (ANSI Standards) developed by Accredited Standards Committees S1, S2, S3, S3/SC 1, and S12 in the areas of acoustics, mechanical vibration and shock, bioacoustics, animal bioacoustics, and noise, respectively, are published by the Acoustical Society of America (ASA). In addition to these standards, ASA publishes a catalog of Acoustical American National Standards. To receive a copy of the latest Standards catalog, please contact Neil Stremmel.Comments are welcomed on all material in Acoustical Standards News.This Acoustical Standards News section in JASA, as well as the National Catalog of Acoustical Standards and other information on the Standards Program of the Acoustical Society of America, are available via the ASA home page: http://acousticalsociety.org. PMID:27475185

  19. Acoustic streaming in microchannels

    DEFF Research Database (Denmark)

    Tribler, Peter Muller

    , the acoustic streaming flow, and the forces on suspended microparticles. The work is motivated by the application of particle focusing by acoustic radiation forces in medical, environmental and food sciences. Here acoustic streaming is most often unwanted, because it limits the focusability of particles...... work. Based on first- and second-order perturbation theory, assuming small acoustic amplitudes, we derived the time-dependent governing equations under adiabatic conditions. The adiabatic first- and second-order equations are solved analytically for the acoustic field between two orthogonally......-of-the-art in the field. Furthermore, the analytical solution for the acoustic streaming in rectangular channels with arbitrary large height-to-width ratios is derived. This accommodates the analytical theory of acoustic streaming to applications within acoustofluidics....

  20. Continued Dispensing: what medications do patients believe should be available?

    Directory of Open Access Journals (Sweden)

    Salem Hasn Abukres

    2015-05-01

    Full Text Available Background. Continued Dispensing (CD is a new medication supply method for certain medications in Australia. It aims to prevent treatment interruption as a result of patients’ inability to obtain a new valid prescription. The only currently eligible patients for this service are statin and/or oral contraceptives users who have been using these medications for 6 months or more, have not utilized the CD method during the last 12 months, and cannot obtain an immediate appointment with the prescriber in order to get a new prescription. This study aimed to investigate patients’ attitudes towards potential extension and expansion of this medication supply method. Methods. A randomly selected 301 users of these medications from all Australian States were recruited using Computer Assisted Telephone Interview (CATI. Result. The response rate was 79%. The majority of the participants (73.3% did not agree with current restriction on CD utilization frequency. They also supported, to varying degrees, inclusion of all the proposed medications (support ranged from 44.2–78.4%. In this regard, participants who suffered from a specific disease did not differ significantly from those without the disease except in case of patients with depression (p = 0.001. Conclusions. Participants of this study strongly supported both CD extension and expansion. A future critical review of the current version of CD is highly recommended in order to enhance CD capability to achieve its goals.

  1. Continued Dispensing: what medications do patients believe should be available?

    Science.gov (United States)

    Abukres, Salem Hasn; Hoti, Kreshnik; Hughes, Jeffery David

    2015-01-01

    Background. Continued Dispensing (CD) is a new medication supply method for certain medications in Australia. It aims to prevent treatment interruption as a result of patients' inability to obtain a new valid prescription. The only currently eligible patients for this service are statin and/or oral contraceptives users who have been using these medications for 6 months or more, have not utilized the CD method during the last 12 months, and cannot obtain an immediate appointment with the prescriber in order to get a new prescription. This study aimed to investigate patients' attitudes towards potential extension and expansion of this medication supply method. Methods. A randomly selected 301 users of these medications from all Australian States were recruited using Computer Assisted Telephone Interview (CATI). Result. The response rate was 79%. The majority of the participants (73.3%) did not agree with current restriction on CD utilization frequency. They also supported, to varying degrees, inclusion of all the proposed medications (support ranged from 44.2-78.4%). In this regard, participants who suffered from a specific disease did not differ significantly from those without the disease except in case of patients with depression (p = 0.001). Conclusions. Participants of this study strongly supported both CD extension and expansion. A future critical review of the current version of CD is highly recommended in order to enhance CD capability to achieve its goals. PMID:26019994

  2. Dynamic behavior of thermionic dispenser cathodes under ion bombardment

    Science.gov (United States)

    Cortenraad, R.; van der Gon, A. W. Denier; Brongersma, H. H.; Gärtner, G.; Raasch, D.; Manenschijn, A.

    2001-04-01

    We have investigated the surface coverage and electron emission of thermionic dispenser cathodes during 3 keV Ar+ ion bombardment, thereby simulating the bombardment of the cathodes by residual gases that takes place in cathode-ray tubes as used in television sets. During the ion bombardment at the operating temperature of 1030 °C, a dynamic equilibrium is established between the sputter removal and resupply mechanisms of the Ba and O atoms that form the dipole layer on the cathode substrate. We demonstrated that the performance of the cathodes under ion bombardment is governed by the O removal and resupply rates. It was found that the Ba resupply rate is almost an order of magnitude higher than the O resupply rate, but that the Ba can only be present on the surface bound to O atoms. Therefore, the Ba/O ratio is approximately equal to unity during the ion bombardment. Based on the investigations of the removal and resupply processes, we proposed a model that accurately describes the surface coverage and electron emission during the ion bombardment, including the dependence of the ion flux and cathode temperature.

  3. Implementation of Multidose Drug Dispensing in a Home Care Setting: Changes in Safety of Medicines Management

    OpenAIRE

    Wekre, Liv Johanne

    2014-01-01

    Multidose dispensed drugs are drugs machine-packed into dose unit bags for each time of administration. Trondheim municipality decided in 2005 to implement Multidose Drug Dispensing (MDD) in home care services. At that time, there was a lack of scientific knowledge about the effects of MDD. The health care management of Trondheim therefore decided to study the implementation in collaboration with NTNU. MDD was adopted gradually during 2006.Three studies were conducted with the common main aim...

  4. A compact and integrated immunoassay with on-chip dispensing and magnetic particle handling.

    Science.gov (United States)

    Zirath, Helene; Peham, Johannes R; Schnetz, Guntram; Coll, Albert; Brandhoff, Lukas; Spittler, Andreas; Vellekoop, Michael J; Redl, Heinz

    2016-02-01

    We present a compact diagnostic platform for a rapid and sensitive detection of plasma biomarkers. The platform consists of a disposable microfluidic polymer chip, a processing device including a lens-free and cost efficient sensor system and a setup for dispersion of magnetic particles. The biomarkers of interest are quantified by magnetic bead based immunoassays with chemiluminescent readout technology. With a novel system for dispersion and manipulation of the magnetic particles in combination with chemiluminescence detection, the sensitivity of the immunoassay is improved and enables a rapid assay in a microfluidic format. In the disposable chip, extra chambers for storage and dispensing of biomarker specific reagents are integrated, which reduce the need of external dosing devices and thereby the cost of the platform is decreased. Plasma biomarkers for monitoring of sepsis could be quantified at 10 pg/mL concentrations within a total time of 30 min by the present system. This contribution is a fundamental step towards the development of an automatic and compact Point-of-Care testing device for monitoring of patients at the intensive care unit.

  5. The principle and physical models of novel jetting dispenser with giant magnetostrictive and a magnifier.

    Science.gov (United States)

    Zhou, C; Li, J H; Duan, J A; Deng, G L

    2015-01-01

    In order to develop jetting technologies of glue in LED and microelectronics packaging, giant-magnetostrictive-material (GMM) is firstly applied to increase jetting response, and a new magnifying device including a lever and a flexible hinge is designed to improve jetting characteristics. Physical models of the jetting system are derived from the magnifying structure and working principle, which involves circuit model, electro-magneto-displacement model, dynamic model and fluid-solid coupling model. The system model is established by combining mathematical models with Matlab-Simulink. The effectiveness of the GMM-based dispenser is confirmed by simulation and experiments. The jetting frequency significantly increases to 250 Hz, and dynamic behaviors jetting needle are evaluated that the velocity and displacement of the jetting needle reaches to 320 mm•s-1 and 0.11 mm respectively. With the increasing of the filling pressure or the amplitude of the current, the dot size will become larger. The dot size and working frequency can be easily adjusted.

  6. The principle and physical models of novel jetting dispenser with giant magnetostrictive and a magnifier

    Science.gov (United States)

    Zhou, C.; Li, J. H.; Duan, J. A.; Deng, G. L.

    2015-12-01

    In order to develop jetting technologies of glue in LED and microelectronics packaging, giant-magnetostrictive-material (GMM) is firstly applied to increase jetting response, and a new magnifying device including a lever and a flexible hinge is designed to improve jetting characteristics. Physical models of the jetting system are derived from the magnifying structure and working principle, which involves circuit model, electro-magneto-displacement model, dynamic model and fluid-solid coupling model. The system model is established by combining mathematical models with Matlab-Simulink. The effectiveness of the GMM-based dispenser is confirmed by simulation and experiments. The jetting frequency significantly increases to 250 Hz, and dynamic behaviors jetting needle are evaluated that the velocity and displacement of the jetting needle reaches to 320 mm•s-1 and 0.11 mm respectively. With the increasing of the filling pressure or the amplitude of the current, the dot size will become larger. The dot size and working frequency can be easily adjusted.

  7. Impact of Robotic Dispensing Machines in German Pharmacies on Business Performance Indicators

    Directory of Open Access Journals (Sweden)

    Ruhle F

    2009-01-01

    Full Text Available Aims and objectives: To assess the impact of robotic dispensing machines in community pharmacies on staff efficiency and sales of over-the-counter drugs. Setting: The study was done on 253 community pharmacies in Germany that use a robotic dispensing machine manufactured by ROWA during 2008. Method: Data concerning the financial and economic impact of using a robotic dispensing machine in community pharmacies was gathered using a structured questionnaire and analysed in terms of its financial implications. Key findings: The response rate was 29%. In most pharmacies (79% the robotic dispensing machine was retrofitted. In 59% of the pharmacies additional space was gained for self-service and behind-the-counter display. As a result of using a robotic dispensing machine, personnel costs were reduced by an average of 4.6% during the first 12 months after start-up. Over-the-counter sales increased in the same period by an average of 6.8%. Despite average initial costs of 118,000 euros, total costs within the first 12 months fell in 50% of cases and at least remained the same in 44%. Conclusions: On average, robotic dispensing machines lead to modest savings in personnel costs and slight increases in sales of over-the-counter drugs. Substantial savings can be achieved only if the staffing level is adapted to the changed personnel requirements.

  8. Separation of prescribing and dispensing in Malaysia: the history and challenges.

    Science.gov (United States)

    Tiong, John Jeh Lung; Mai, Chun Wai; Gan, Pou Wee; Johnson, James; Mak, Vivienne Sook Li

    2016-08-01

    This article serves as an update to the work by Shafie et al. (2012) which previously reviewed the benefits of policies separating prescribing and dispensing in various countries to advocate its implementation in Malaysia. This article seeks to strengthen the argument by highlighting not only the weaknesses of the Malaysian health care system from the historical, professional and economic viewpoints but also the shortcomings of both medical and pharmacy professions in the absence of separation of dispensing. It also provides a detailed insight into the ongoing initiatives taken to consolidate the role of pharmacists in the health care system in the advent of separation of dispensing. Under the two tier system in Malaysia at present, the separation of prescribing and dispensing is implemented only in government hospitals. The absence of this separation in the private practices has led to possible profit-oriented medical and pharmacy practices which hinder safe and cost-effective delivery of health services. The call for separation of dispensing has gained traction over the years despite various hurdles ranging from the formidable resistance from the medical fraternity to the public's scepticism towards the new policy. With historical testament and present evidence pointing towards the merits of a system in which doctors prescribe and pharmacists dispense, the implementation of this health care model is justified.

  9. Separation of prescribing and dispensing in Malaysia: the history and challenges.

    Science.gov (United States)

    Tiong, John Jeh Lung; Mai, Chun Wai; Gan, Pou Wee; Johnson, James; Mak, Vivienne Sook Li

    2016-08-01

    This article serves as an update to the work by Shafie et al. (2012) which previously reviewed the benefits of policies separating prescribing and dispensing in various countries to advocate its implementation in Malaysia. This article seeks to strengthen the argument by highlighting not only the weaknesses of the Malaysian health care system from the historical, professional and economic viewpoints but also the shortcomings of both medical and pharmacy professions in the absence of separation of dispensing. It also provides a detailed insight into the ongoing initiatives taken to consolidate the role of pharmacists in the health care system in the advent of separation of dispensing. Under the two tier system in Malaysia at present, the separation of prescribing and dispensing is implemented only in government hospitals. The absence of this separation in the private practices has led to possible profit-oriented medical and pharmacy practices which hinder safe and cost-effective delivery of health services. The call for separation of dispensing has gained traction over the years despite various hurdles ranging from the formidable resistance from the medical fraternity to the public's scepticism towards the new policy. With historical testament and present evidence pointing towards the merits of a system in which doctors prescribe and pharmacists dispense, the implementation of this health care model is justified. PMID:26777986

  10. DEVELOPMENT OF A BACTERIAL CULTURE SYSTEM USING A PAPER PLATFORM TO ACCOMMODATE MEDIA AND AN INK-JET PRINTING TO DISPENSE BACTERIA

    Directory of Open Access Journals (Sweden)

    Tithimanan Srimongkon

    2014-01-01

    Full Text Available Generally, bacterial culture is performed manually and is subject to error. Here, we created a novel, well-ordered and reliable system for dispensing bacteria microscopically by using paper and an ink-jet printer for controlled patterning. For paper to accommodate a culture medium, hydrophobic/hydrophilic patterns were incorporated onto the paper by immersing paper in a toluene solution of polystyrene and drying for complete hydrophobization, followed by etching discrete, small areas of hydrophilicity by ink-jet printing with toluene. Agar was hydrolyzed with sulfuric acid for appropriate viscosity and dispensed with an ink-jet printer. In a separate experiment, bacterial cells were sequentially printed on a medium and colonies were observed microscopically. The results of this experiment ensured the successful dispensing of bacteria using ink-jet printing. An almost constant number of particles per droplet were ejected using a polystyrene latex as a model of bacterial dispersion. Consequently, we expect this technology to be adapted for the development of a paper-based bioassay system.

  11. Exploitation of Acoustic signature of Low flying Aircraft using Acoustic Vector Sensor

    Directory of Open Access Journals (Sweden)

    A. Saravanakumar

    2014-03-01

    Full Text Available Acoustics is emerging as a significant complementary modality to be explored and exploited in the development of Intelligence and surveillance systems that traditionally rely on technology rooted in electro-magnetic field phenomena. Acoustics is emerging as a significant complementary modality to be explored and exploited in the development of Intelligence and surveillance systems that traditionally rely on technology rooted in electro-magnetic field phenomena. An application of the current interest is the detection and localization of the sound sources on battlefield using Acoustic sensors in ground and on board unmanned aerial vehicle. In this work a nonlinear least-square cepstrum and auto correlation methods are made to estimate the motion parameters of a low flying aircraft whose narrowband acoustic energy emissions were received by a ground-based Acoustic vector sensor. The data obtained from the sensor were processed and analyzed using digital signal processing approach. This passive technique is applied to real acoustic sensor data under the condition that the vehicle flies at a constant velocity and the trajectory is a straight line. The performances of both methods are evaluated and compared using actual acoustic data.Defence Science Journal, 2014, 64(2, pp. 95-98. DOI: http://dx.doi.org/10.14429/dsj.64.3924 

  12. 基于声波技术的管道泄漏检测与定位系统的研究%Research on detection and location system of pipeline leakage based on acoustic wave technology

    Institute of Scientific and Technical Information of China (English)

    付光杰; 赵丹; 赵庆峰; 王士勇

    2015-01-01

    The online real-time leakage detection and location system of natural gas pipeline leak source makes the leakage can be discovered in time,which can confirm leak source location accurately. The economic losses caused by natural gas leakage can be reduced,and it has profound significance for improving automated management level of natural gas transportation pipe-line. By studying and comparative analyzing to pipeline detection technology at home and abroad,acoustic wave technology is ap-plied to leakage detection of gas pipeline. The real-time acoustic wave monitoring and location system for natural gas line leakage was designed by virtual instrument software to proceed signal processing. The leaked acoustic wave signal is proceeded with waveform real-time display,digital filtering,correlated calculation,leakage location and other operations. The automation of pipeline leakage detection was realized.%天然气管道漏点在线实时泄漏监测与定位系统的研究与应用,使得泄漏能够被及时发现并确定泄漏点的位置,从而降低因天然气泄漏造成的经济损失,同时对提高天然气输送管线的自动化管理水平有着深远的意义.通过对国内外各种管道泄漏检测技术的研究和分析比较,采用声波检测方法应用于输气管道的泄漏检测策略,在信号处理方面采用虚拟仪器软件设计了天然气管线声波泄漏实时监测定位系统,对泄漏声波信号进行波形实时显示、数字滤波、相关运算以及泄漏点定位等操作,实现了管线泄漏检测的自动化.

  13. Simultaneous measurements of room acoustic parameters using different measuring equipment

    DEFF Research Database (Denmark)

    Halmrast, Tor; Gade, Anders Christian; Winsvold, Bjørn

    1996-01-01

    In a cooperation between Stattsbyg, Norway, Norsonic, Norway, and Department of Acoustic Technology, a number of room acoustic parameters have been determined in Oslo Concert Hall. All measurements were carried out on the same day, using the same amplifier, microphone and loudspeaker, and the sam...

  14. A novel blending method for dispensing powdered medicine.

    Science.gov (United States)

    Miyazaki, Yasunori; Miyawaki, Kaoru; Uchino, Tomonobu; Kagawa, Yoshiyuki

    2014-01-01

    We introduced the application of a planetary centrifugal mixer to dispensing powdered medicines to prevent from individual variation in the skills of pharmacists with a manual blending. The blending performance of the mixer was explored in terms of four operational variables, namely, operation speed (400-1000 rpm), operation time (10-60 s), charging rate in vessel (20-50%), and size of vessel (35, 58, 125, 550 mL), using colored lactose and crystalline lactose as the principle model medicine and diluent, respectively. The blending degree was assessed by image analysis, so the extent of uniformity was expressed as the relative standard deviation of the color difference signal Cb value of YCrCb color space. Application of the mixer to blending three commercial medicines with diluents was carried out. Sufficient blending was achieved at 10 s using a 20% charging rate and 35 mL vessel irrespective of operation speed. As the charging rate was increased, a higher operation speed was needed to obtain uniform blending. A larger sized vessel also required a higher operation speed. Uniform blending was achieved in all of the mixtures of colored lactose and crystalline lactose at the weight ratio of 1 : 9-9 : 1. In the application studies using Adona®, Anginal® and Neophylline® powder, the blending performance of the mixer was equivalent to that of the manual blending method, showing relative standard deviations of 2.2-3.3% and 1.8-3.8%, respectively. These results revealed that the planetary centrifugal mixer was suitable for blending powdered medicine. PMID:24390492

  15. Type I IFN Signaling Is Dispensable during Secondary Viral Infection.

    Science.gov (United States)

    Hosking, Martin P; Flynn, Claudia T; Whitton, J Lindsay

    2016-08-01

    Innate immune responses in general, and type I interferons (T1IFNs) in particular, play an important and often essential role during primary viral infections, by directly combatting the virus and by maximizing the primary adaptive immune response. Several studies have suggested that T1IFNs also contribute very substantially to the secondary (recall) response; they are thought (i) to be required to drive the early attrition of memory T cells, (ii) to support the subsequent expansion of surviving virus-specific memory cells, and (iii) to assist in the suppression and clearance of the infectious agent. However, many of these observations were predicated upon models in which T1IFN signaling was interrupted prior to a primary immune response, raising the possibility that the resulting memory cells might be intrinsically abnormal. We have directly addressed this by using an inducible-Cre model system in which the host remains genetically-intact during the primary response to infection, and in which T1IFN signaling can be effectively ablated prior to secondary viral challenge. We report that, in stark contrast to primary infection, T1IFN signaling is not required during the recall response. IFNαβR-deficient memory CD8+ and CD4+ memory T cells undergo attrition and expansion with kinetics that are indistinguishable from those of receptor-sufficient cells. Moreover, even in the absence of functional T1IFN signaling, the host's immune capacity to rapidly suppress, and then to eradicate, a secondary infection remains intact. Thus, this study shows that T1IFN signaling is dispensable during the recall response to a virus infection. Moreover, two broader implications may be drawn. First, a T cell's requirement for a cytokine is highly dependent on the cell's maturation / differentiation status. Consequently, second, these data underscore the importance of evaluating a gene's impact by modulating its expression or function in a temporally-controllable manner. PMID:27580079

  16. Justice Dispensation through the Alternative Dispute Resolution System in India

    Directory of Open Access Journals (Sweden)

    Krishna Agrawal

    2014-01-01

    Full Text Available The Law Commission of India in its 222nd report emphasized the need for Alternative Disputes Resolution (ADR for the dispensation of justice, because the courts are inaccessible owing to various factors, e.g., poverty, social and political backwardness, illiteracy, ignorance, procedural formalities and inordinate delay in judgments. During the ancient period the disputes were resolved in an informal manner by neutral third persons or people’s court in villages and it continued till the middle of the 20th century. Unfortunately, after the Independence of India in 1947, this system was dissuaded and the government permitted to continue the adversarial system of justice. In 1980, a committee was set up. It recommended Lok Adalats (People’s Courts. In 1987, the Legal Services Authorities Act was enacted. This Act obligates the states to provide free legal aid to poor persons. Besides this, the Act provides for the establishment of permanent Lok Adalats.This is one of the important modes of ADR. Lok Adalats have been established in all the districts of the country. They bring conciliatory settlement in complicated cases arising out of matrimonial, landlord-tenants, property, insurance and commercial disputes. There are four methods of ADR, viz., negotiation, mediation, conciliation and arbitration. Mediation and arbitration are widely preferred. They are alternatives to litigation. The Arbitration Act for the first time was enacted in 1889 and it was subsequently amended many times. On the objections raised by the Supreme Court of India and also on the adoption of UNCITRAL Model Law on International Commercial Arbitration, in 1996 Arbitration and Conciliation Act was enacted. This law is almost the same as is almost in all the countries.Further, the Government of India established International Centre for Alternative Disputes Resolution (CADR with the objectives of promotion, propagation, and popularizing the settlement of domestic and

  17. Springer handbook of acoustics

    CERN Document Server

    2014-01-01

    Acoustics, the science of sound, has developed into a broad interdisciplinary field encompassing the academic disciplines of physics, engineering, psychology, speech, audiology, music, architecture, physiology, neuroscience, and electronics. The Springer Handbook of Acoustics is also in his 2nd edition an unparalleled modern handbook reflecting this richly interdisciplinary nature edited by one of the acknowledged masters in the field, Thomas Rossing. Researchers and students benefit from the comprehensive contents. This new edition of the Handbook features over 11 revised and expanded chapters, new illustrations, and 2 new chapters covering microphone arrays  and acoustic emission.  Updated chapters contain the latest research and applications in, e.g. sound propagation in the atmosphere, nonlinear acoustics in fluids, building and concert hall acoustics, signal processing, psychoacoustics, computer music, animal bioacousics, sound intensity, modal acoustics as well as new chapters on microphone arrays an...

  18. Vibro-acoustics

    CERN Document Server

    Nilsson, Anders

    2015-01-01

    This three-volume book gives a thorough and comprehensive presentation of vibration and acoustic theories. Different from traditional textbooks which typically deal with some aspects of either acoustic or vibration problems, it is unique of this book to combine those two correlated subjects together. Moreover, it provides fundamental analysis and mathematical descriptions for several crucial phenomena of Vibro-Acoustics which are quite useful in noise reduction, including how structures are excited, energy flows from an excitation point to a sound radiating surface, and finally how a structure radiates noise to a surrounding fluid. Many measurement results included in the text make the reading interesting and informative. Problems/questions are listed at the end of each chapter and the solutions are provided. This will help the readers to understand the topics of Vibro-Acoustics more deeply. The book should be of interest to anyone interested in sound and vibration, vehicle acoustics, ship acoustics and inter...

  19. PREVENTING LITHOGRAPHY-INDUCED MAVERICK YIELD EVENTS WITH A DISPENSE SYSTEM ADVANCED EQUIPMENT CONTROL METHOD

    Institute of Scientific and Technical Information of China (English)

    Jennifer Broggin

    2012-01-01

    As semiconductor manufacturers march to thedrum beat of Moore's Law there is very little roomfor yield maverieks, especially those that can beprevented. Critical process errors are costly andphotolithography is one of the few processes insemiconductor manufacturing where there is anopportunity to correct errors. Small changes inphotoresist-dispensed volume may have severeimpact on film thickness uniformity and can ulti-mately affect patterning It is important to monitorphoto dispense conditions to detect real-timeevents that may have a direct negative impact onprocess yield and be able to react to these eventsas quickly as possible.This paper presents an evaluation of the IntelliGen Mini, a photoresist dispense system manufacturedby Entegris, Inc. This system utilizes advancedequipment control software, known as dispenseconfirmation, to detect variations in photo dis-pense. These variations, caused by bubbles inthe dispense line, valve errors and accidentally-changed chemistries can all create maverick yieldevents that can go undetected until metrology,defeet inspection or wafer final testThe ability of an advanced dispense system todetect events and create alerts is a very powerfultool, but it can be most effective when that infor-mation is collected and analyzed by an automatedsystem. In a modern fabricator this is most likely astatistical process control chart that is monitoringa track's progress and is ready to stop the trackwhen a maverick event occurs or alert personnelto trends they may not otherwise catch with otherinline ntetrology data. Dispense confirmation,when Combined with networking capabilities,can meet this need.After a brief description of the pump, data from sim-ulated yield-affecting events will be examined toevaluate the IntelliGen Mini's ability to detect them.This discussion will eonclude with a brief analysisof the ultilnate time and cost savings of utilizingdispense confirmation with networking capabilitiesto detect and eliminate poorly

  20. Shallow Water Acoustic Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Supports experimental research where high-frequency acoustic scattering and surface vibration measurements of fluid-loaded and non-fluid-loaded structures...

  1. Low frequency acoustic microscope

    Science.gov (United States)

    Khuri-Yakub, Butrus T.

    1986-11-04

    A scanning acoustic microscope is disclosed for the detection and location of near surface flaws, inclusions or voids in a solid sample material. A focused beam of acoustic energy is directed at the sample with its focal plane at the subsurface flaw, inclusion or void location. The sample is scanned with the beam. Detected acoustic energy specularly reflected and mode converted at the surface of the sample and acoustic energy reflected by subsurface flaws, inclusions or voids at the focal plane are used for generating an interference signal which is processed and forms a signal indicative of the subsurface flaws, inclusions or voids.

  2. Handbook of Engineering Acoustics

    CERN Document Server

    Möser, Michael

    2013-01-01

    This book examines the physical background of engineering acoustics, focusing on empirically obtained engineering experience as well as on measurement techniques and engineering methods for prognostics. Its goal is not only to describe the state of art of engineering acoustics but also to give practical help to engineers in order to solve acoustic problems. It deals with the origin, the transmission and the methods of the abating different kinds of air-borne and structure-borne sounds caused by various mechanisms – from traffic to machinery and flow-induced sound. In addition the modern aspects of room and building acoustics, as well as psychoacoustics and active noise control, are covered.

  3. Localized acoustic surface modes

    Science.gov (United States)

    Farhat, Mohamed; Chen, Pai-Yen; Bağcı, Hakan

    2016-04-01

    We introduce the concept of localized acoustic surface modes. We demonstrate that they are induced on a two-dimensional cylindrical rigid surface with subwavelength corrugations under excitation by an incident acoustic plane wave. Our results show that the corrugated rigid surface is acoustically equivalent to a cylindrical scatterer with uniform mass density that can be represented using a Drude-like model. This, indeed, suggests that plasmonic-like acoustic materials can be engineered with potential applications in various areas including sensing, imaging, and cloaking.

  4. Localized Acoustic Surface Modes

    KAUST Repository

    Farhat, Mohamed

    2015-08-04

    We introduce the concept of localized acoustic surface modes (ASMs). We demonstrate that they are induced on a two-dimensional cylindrical rigid surface with subwavelength corrugations under excitation by an incident acoustic plane wave. Our results show that the corrugated rigid surface is acoustically equivalent to a cylindrical scatterer with uniform mass density that can be represented using a Drude-like model. This, indeed, suggests that plasmonic-like acoustic materials can be engineered with potential applications in various areas including sensing, imaging, and cloaking.

  5. Occurrence of heterotrophic and coliform bacteria in liquid hand soaps from bulk refillable dispensers in public facilities.

    Science.gov (United States)

    Chattman, Marisa; Gerba, Sheri L; Maxwell, Charles P

    2011-03-01

    The goal of the study discussed in this article was to determine the occurrence of heterotrophic and coliform bacteria in liquid soap from bulk refillable dispensers, obtained from restrooms in a variety of public facilities. A total of 541 samples was collected from five U.S. cities. Liquid soap from dispensers in public areas was found to contain heterotrophic and coliform bacterial numbers averaging more than 106 CFU/mL in 24.8% of the dispensers.

  6. What Is an Acoustic Neuroma

    Science.gov (United States)

    ... org Connect with us! What is an Acoustic Neuroma? Each heading slides to reveal information. Important Points ... Neuroma Important Points To Know About an Acoustic Neuroma An acoustic neuroma, also called a vestibular schwannoma, ...

  7. The design and control of a jetting dispenser for semiconductor electronic packaging driven by a piezostack and a flexible beam

    International Nuclear Information System (INIS)

    This paper presents the performance characteristics of a new type of jetting dispenser which can be applicable for modern semiconductor packaging processes. The proposed jetting dispenser is driven by both a piezostack actuator and a flexible beam mechanism. After describing the geometric configuration and operational principle of the dispenser, a mathematical model of the system is derived by considering the dynamic behaviors of structural parts such as the piezostack, the flexible beam, the needle structure, and the adhesive fluid dynamics. In the modeling, a lumped parameter method is employed and the governing equation of the whole dispenser is then formulated by integrating the structural model with the fluid model. Based on the proposed model, significant structural components of the dispenser such as the piezostack, the flexible beam, and the actuating spring are designed in order to achieve operational requirements (needle motion amplitude: up to 0.4 mm; operating frequency: up to 700 Hz). Subsequently, dispensing performances such as the dispensing dot size and flow rate are experimentally evaluated. In addition, a control algorithm is designed and empirically realized to demonstrate some benefits of the proposed jetting dispenser such as accurate controllability of dispensing amount

  8. Humanitarian mine detection by acoustic resonance

    Energy Technology Data Exchange (ETDEWEB)

    Kercel, S.W.

    1998-03-01

    The JASON Committee at MITRE Corp. was tasked by DARPA to inquire into suitable technologies for humanitarian mine detection. Acoustic resonance was one of the very few technologies that the JASONs determined might be promising for the task, but was as yet unexplored at the time that they conducted their inquiry. The objective of this Seed Money investigation into acoustic resonance was to determine if it would be feasible to use acoustic resonance to provide an improvement to present methods for humanitarian mine detection. As detailed in this report, acoustic resonance methods do not appear to be feasible for this task. Although acoustic resonant responses are relatively easy to detect when they exist, they are very difficult to excite by the non-contact means that must be used for buried objects. Despite many different attempts, this research did not discover any practical means of using sound to excite resonant responses in objects known to have strong resonances. The shaker table experiments did see an effect that might be attributable to the resonance of the object under test, but the effect was weak, and exploited the a priori knowledge of the resonant frequency of the object under test to distinguish it from the background. If experiments that used objects known to have strong acoustic resonances produced such marginal results, this does not seem to be a practical method to detect objects with weak resonances or non-existent resonances. The results of this work contribute to the ORNL countermine initiative. ORNL is exploring several unconventional mine detection technologies, and is proposed to explore others. Since this research has discovered some major pitfalls in non-metallic mine detection, this experience will add realism to other strategies proposed for mine detection technologies. The experiment provided hands-on experience with inert plastic mines under field conditions, and gives ORNL additional insight into the problems of developing practical

  9. Applying of the array transducers' technology for surface acoustic waves materials characterization in the transient regime; Application de la technologie multi-elements a la caracterisation des materiaux par ondes acoustiques de surface en regime impulsionnel

    Energy Technology Data Exchange (ETDEWEB)

    Frenet, D

    2000-07-01

    In this document we present a theoretical and experimental study which has been led to design a surface acoustic wave device for local characterisation (relatively to the wavelength) of isotropic or anisotropic materials. The device is based on a phased-array transducer of conical shape we have specifically designed for this purpose. It operates in the impulsive mode, in the frequency range of 1-5 MHz. In order to deduce mechanical properties of the material, it is possible to measure the surface wave characteristics (velocity, attenuation,...). Different methods for measuring the wave velocity have been developed taking advantage of from the phased-array technology. The originality of theses methods relies on the fact that the measures are performed without moving the transducer. Consequently, the device requires no additional mechanical system and it is quite compact. In addition, this shortens the characterisation process duration comparatively to the usually available methods (e. g. the V(z) technique). In the theoretical section of this study, a versatile model allowing to simulate in the time harmonic regime as well as in the transient regime, the transmitted field, the field reflected on isotropic or anisotropic planar samples and the output voltage for transducers of arbitrary shapes has been developed. The model has been applied to the phased-array conical transducer as well as to more classical transducers such as planar (rectangular) or focusing (spherically or cylindrically shaped) transducers. It predicts not only the geometrical contributions of the reflected field and signal but also the leaky contributions related to the surface acoustic waves. (author)

  10. Advanced Concepts for Underwater Acoustic Channel Modeling

    Science.gov (United States)

    Etter, P. C.; Haas, C. H.; Ramani, D. V.

    2014-12-01

    This paper examines nearshore underwater-acoustic channel modeling concepts and compares channel-state information requirements against existing modeling capabilities. This process defines a subset of candidate acoustic models suitable for simulating signal propagation in underwater communications. Underwater-acoustic communications find many practical applications in coastal oceanography, and networking is the enabling technology for these applications. Such networks can be formed by establishing two-way acoustic links between autonomous underwater vehicles and moored oceanographic sensors. These networks can be connected to a surface unit for further data transfer to ships, satellites, or shore stations via a radio-frequency link. This configuration establishes an interactive environment in which researchers can extract real-time data from multiple, but distant, underwater instruments. After evaluating the obtained data, control messages can be sent back to individual instruments to adapt the networks to changing situations. Underwater networks can also be used to increase the operating ranges of autonomous underwater vehicles by hopping the control and data messages through networks that cover large areas. A model of the ocean medium between acoustic sources and receivers is called a channel model. In an oceanic channel, characteristics of the acoustic signals change as they travel from transmitters to receivers. These characteristics depend upon the acoustic frequency, the distances between sources and receivers, the paths followed by the signals, and the prevailing ocean environment in the vicinity of the paths. Properties of the received signals can be derived from those of the transmitted signals using these channel models. This study concludes that ray-theory models are best suited to the simulation of acoustic signal propagation in oceanic channels and identifies 33 such models that are eligible candidates.

  11. A MEMS Flow Sensor for Self-adjusted Precise Non-Contact Liquid Dispensing

    Directory of Open Access Journals (Sweden)

    Liu Yaxin

    2013-01-01

    Full Text Available A MEMS flow sensor was proposed to enhance the reliability and accuracy of liquid dispensing system. Benefiting from the feedback of sensor information, the system can self-adjust the open time of the solenoid vale to accurately dispensing desired reagent volume without pre-calibration. This study focuses on the design, fabrication and application of this flow sensor. Firstly, the design, fabrication and characteristics of the MEMS flow sensor based on the measurement of the pressure difference across a flow channel are presented. Secondly, the liquid dispensing system in which the flow sensor is integrated will be introduced. A novel closed-loop control strategy is proposed to calculate valve open-time for each dispensing cycle. Finally, experiments results are presented with different dispensing volumes, Coefficient of Variance (CV has been shown to be below 3%. It indicates that integration of the MEMS flow sensor and using of a compound intelligent control strategy make the system immune to liquid viscosity, pressure fluctuation and some other disturbances.

  12. [Dispensing specialized component medicines in areas of the State of Rio de Janeiro].

    Science.gov (United States)

    Lima-Dellamora, Elisangela da Costa; Caetano, Rosangela; Osorio-de-Castro, Claudia Garcia Serpa

    2012-09-01

    The Specialized Pharmaceutical Services Component (CEAF) ensures the dispensing of high-cost medicines for the treatment of specific diseases. The fact that these medicines are mandatory though access is only through legal injunctions, suggests flaws in the management of pharmaceutical services. This paper analyzed adherence to Clinical Protocols and Therapeutic Guidelines (PCDT) in the dispensing of these CEAF medicines. Qualitative research was also conducted in facilities with different characteristics in the State of Rio de Janeiro. It was noted that the lack of adequate structure in the units studied, including trained personnel, compromises the dispensing CEAF medicines in all facilities. The CEAF dispensing procedure, heavily dependent on interaction between prescribers and dispensers, is not carried out as would be expected. It is possible that inadequate performance is also linked to flaws in the planning and organization of services. The results indicate barriers in adherence to PCDT by health professionals, prejudicing health system users and possibly leading them to access medicines by legal means. It is believed that characteristics of the investigated facilities are similar to others in Brazil, and the barriers identified may be the same, compromising healthcare.

  13. Optimizing Aerosol Dispensers for Mating Disruption of Codling Moth, Cydia pomonella L.

    Science.gov (United States)

    McGhee, Peter S; Miller, James R; Thomson, Donald R; Gut, Larry J

    2016-07-01

    Experiments were conducted in commercial apple orchards to determine if improved efficiencies in pheromone delivery may be realized by using aerosol pheromone dispensers for codling moth (CM), Cydia pomonella L., mating disruption. Specifically, we tested how reducing: pheromone concentration, period of dispenser operation, and frequency of pheromone emission from aerosol dispensers affected orientational disruption of male CM to pheromone-baited monitoring traps. Isomate® CM MIST formulated with 50 % less codlemone (3.5 mg/ emission) provided orientation disruption equal to the standard commercial formulation (7 mg / emission). Decreased periods of dispenser operation (3 and 6 h) and frequency of pheromone emission (30 and 60 min) provided a level of orientational disruption similar to the current standard protocol of releasing pheromone over a 12 h period on a 15 min cycle, respectively. These three modifications provide a means of substantially reducing the amount of pheromone necessary for CM disruption. The savings accompanying pheromone conservation could lead to increased adoption of CM mating disruption and, moreover, provide an opportunity for achieving higher levels of disruption by increasing dispenser densities. PMID:27369280

  14. Predicting Acoustics in Class Rooms

    DEFF Research Database (Denmark)

    Christensen, Claus Lynge; Rindel, Jens Holger

    2005-01-01

    Typical class rooms have fairly simple geometries, even so room acoustics in this type of room is difficult to predict using today's room acoustic computer modeling software. The reasons why acoustics of class rooms are harder to predict than acoustics of complicated concert halls might be explai......Typical class rooms have fairly simple geometries, even so room acoustics in this type of room is difficult to predict using today's room acoustic computer modeling software. The reasons why acoustics of class rooms are harder to predict than acoustics of complicated concert halls might...... with surface scattering is presented. Each of the two scattering effects is modeled as frequency dependent functions....

  15. Patient attitudes towards a new role for pharmacists: continued dispensing

    Directory of Open Access Journals (Sweden)

    Abukres SH

    2014-08-01

    Full Text Available Salem Hasn Abukres, Kreshnik Hoti, Jeffery David Hughes School of Pharmacy, Curtin Health and Innovation Research Institute, Curtin University, Perth, WA, Australia Background: In Australia, “continued dispensing” (CD is a new model for supply of prescription medications. Under specific circumstances, community pharmacists are allowed to dispense a further one month supply of prescription only medications without a valid prescription. It allows continuation and treatment adherence when patients run out of statin and/or oral contraceptive (OC medications, when it is not practical or they fail to plan accordingly to get a new prescription. Objective: The aim of this study was to explore patient attitudes towards a CD model, including any perceived concerns or associated risks with CD prior to its introduction.Methods: An Australia-wide computer-assisted telephone interview survey of statin and OC users aged 18 years or older was conducted in July 2013 prior to implementation of the CD model. A telephone number list was generated via a random number generation function based on a broad breakdown of the Australian population as outlined in the June 2013 Australian Bureau of Statistics data. The sample target for the survey was 300, consisting of 150 statin users and 150 OC users.Results: There were a total of 301 respondents, comprising 151 statin users and 150 OC users. Approximately 37% of all respondents had experienced running out of their medications in the past 12 months, of whom 35.4% had temporarily stopped treatment and 33.6% requested their medication from a pharmacist without a valid prescription. OC users were more likely to run out of their medications (P=0.021. The majority of respondents had a regular pharmacy (86% and therefore would be eligible for CD in the future. The majority of those surveyed had no concerns about CD or perceived it as posing no risks. Concerns raised included consultation privacy and the pharmacist’s lack

  16. Research on the influence and correction method of depth scanning error to the underwater acoustic image measurement

    Institute of Scientific and Technical Information of China (English)

    MEI Jidan; ZHAI Chunpin; WANGYilin; HUI Junying

    2011-01-01

    The technology of underwater acoustic image measurement was a passive locating method with high precision in near field. To improve the precision of underwater acoustic image measurement, the influence of the depth scan error was analyzed and the correcti

  17. Preserving the acoustical heritage of historical buildings

    DEFF Research Database (Denmark)

    Rindel, Jens Holger

    2005-01-01

    The use of virtual reality and auralization techniques has opened new possibilities for the study of acoustical conditions in historic buildings. With reference to some recent and current projects the paper describes the steps in the process and how new technology may be used to overcome some of ...

  18. Ocean acoustic reverberation tomography.

    Science.gov (United States)

    Dunn, Robert A

    2015-12-01

    Seismic wide-angle imaging using ship-towed acoustic sources and networks of ocean bottom seismographs is a common technique for exploring earth structure beneath the oceans. In these studies, the recorded data are dominated by acoustic waves propagating as reverberations in the water column. For surveys with a small receiver spacing (e.g., ocean acoustic reverberation tomography, is developed that uses the travel times of direct and reflected waves to image ocean acoustic structure. Reverberation tomography offers an alternative approach for determining the structure of the oceans and advancing the understanding of ocean heat content and mixing processes. The technique has the potential for revealing small-scale ocean thermal structure over the entire vertical height of the water column and along long survey profiles or across three-dimensional volumes of the ocean. For realistic experimental geometries and data noise levels, the method can produce images of ocean sound speed on a smaller scale than traditional acoustic tomography.

  19. Acoustic Signals and Systems

    DEFF Research Database (Denmark)

    2008-01-01

    The Handbook of Signal Processing in Acoustics will compile the techniques and applications of signal processing as they are used in the many varied areas of Acoustics. The Handbook will emphasize the interdisciplinary nature of signal processing in acoustics. Each Section of the Handbook...... will present topics on signal processing which are important in a specific area of acoustics. These will be of interest to specialists in these areas because they will be presented from their technical perspective, rather than a generic engineering approach to signal processing. Non-specialists, or specialists...... from different areas, will find the self-contained chapters accessible and will be interested in the similarities and differences between the approaches and techniques used in different areas of acoustics....

  20. Ocean acoustic hurricane classification.

    Science.gov (United States)

    Wilson, Joshua D; Makris, Nicholas C

    2006-01-01

    Theoretical and empirical evidence are combined to show that underwater acoustic sensing techniques may be valuable for measuring the wind speed and determining the destructive power of a hurricane. This is done by first developing a model for the acoustic intensity and mutual intensity in an ocean waveguide due to a hurricane and then determining the relationship between local wind speed and underwater acoustic intensity. From this it is shown that it should be feasible to accurately measure the local wind speed and classify the destructive power of a hurricane if its eye wall passes directly over a single underwater acoustic sensor. The potential advantages and disadvantages of the proposed acoustic method are weighed against those of currently employed techniques. PMID:16454274

  1. Cochlear bionic acoustic metamaterials

    Science.gov (United States)

    Ma, Fuyin; Wu, Jiu Hui; Huang, Meng; Fu, Gang; Bai, Changan

    2014-11-01

    A design of bionic acoustic metamaterial and acoustic functional devices was proposed by employing the mammalian cochlear as a prototype. First, combined with the experimental data in previous literatures, it is pointed out that the cochlear hair cells and stereocilia cluster are a kind of natural biological acoustic metamaterials with the negative stiffness characteristics. Then, to design the acoustic functional devices conveniently in engineering application, a simplified parametric helical structure was proposed to replace actual irregular cochlea for bionic design, and based on the computational results of such a bionic parametric helical structure, it is suggested that the overall cochlear is a local resonant system with the negative dynamic effective mass characteristics. There are many potential applications in the bandboard energy recovery device, cochlear implant, and acoustic black hole.

  2. Computational Ocean Acoustics

    CERN Document Server

    Jensen, Finn B; Porter, Michael B; Schmidt, Henrik

    2011-01-01

    Since the mid-1970s, the computer has played an increasingly pivotal role in the field of ocean acoustics. Faster and less expensive than actual ocean experiments, and capable of accommodating the full complexity of the acoustic problem, numerical models are now standard research tools in ocean laboratories. The progress made in computational ocean acoustics over the last thirty years is summed up in this authoritative and innovatively illustrated new text. Written by some of the field's pioneers, all Fellows of the Acoustical Society of America, Computational Ocean Acoustics presents the latest numerical techniques for solving the wave equation in heterogeneous fluid–solid media. The authors discuss various computational schemes in detail, emphasizing the importance of theoretical foundations that lead directly to numerical implementations for real ocean environments. To further clarify the presentation, the fundamental propagation features of the techniques are illustrated in color. Computational Ocean A...

  3. Precision dispensing of small volumes of albumin solder for laser-assisted wound closure

    Science.gov (United States)

    Sorg, Brian S.; McNally-Heintzelman, Karen M.; Chan, Eric K.; Frederickson, Christopher J.; Welch, Ashley J.

    1999-06-01

    Recent laser-tissue soldering work in our lab has demonstrated the feasibility of building a solder bond from individually coagulated small droplets using a precision pipette for the deposition of the solder droplets. This method of using small, precise volumes of solder to build a bond may result in stronger and more reproducible bonds than coagulating an equivalent large volume of solder all at once. We have investigated the technique further in this study. The solder was dispensed onto the intimal side of a bovine aorta substrate and irradiated with an 808nm diode laser. A bond was created across an incision in the tissue substrate by alternately dispensing and coagulating each small volume of solder, or by coagulating a single large equivalent volume. Acute strength analysis was performed on the solder bond. Future work will concentrate on testing a bench-top solder dispensing device and investigating the feasibility of turning the deice into a prototype tool for clinical applications.

  4. Estimation of inbreeding from ecclesiastical dispensations: application of three procedures to a Spanish case.

    Science.gov (United States)

    Fuster, Vicente; Colantonio, Sonia

    2002-07-01

    The inbreeding coefficient of a population, estimated from ecclesiastical Roman Catholic dispensations, results from the relative contribution of different degrees of relationships (uncle-niece, first cousin, etc.). The interpopulation comparisons of consanguinity patterns may be obscured by the fact that in 1918 the Roman Catholic Church norm regulating the closest marriageable kinship was modified, limiting the application for an ecclesiastical dispensation to relatives of third degree (second cousins) or closer. Depending on the length of the period before or after the change of regulation, coefficients and rates may differ. Deviation of frequencies for multiple marriages may also occur. The aim of the present paper is to determine how the chosen procedure based on ecclesiastical dispensations may affect results, regarding the inbreeding coefficient, the consanguinity rate, the structure of consanguinity and the close/remote kinship ratio. As a sample case, information from the Gredos mountain range (central Spain) has been used. PMID:12117217

  5. Orthotics, prosthesis and mobility aids (OPM dispensation in the Regional Health Department of the 3RD Region of Sao Paulo State

    Directory of Open Access Journals (Sweden)

    Camila Caminha Caro

    2014-12-01

    Full Text Available Objective: To identify the process of dispensation of orthotics, prostheses and mobility aids (OPM by the Unified Health System (SUS in the Regional Health Department of the 3rd Region (DRSIII of Sao Paulo state; perform a mapping of the existing physical rehabilitation services in that region; and subsequently correlate the data with applicable laws. Methodology: This is an exploratory cross-sectional qualitative study whose subjects were the main professionals involved in the process of OPM dispensation, or responsible for their acquisition flow in the cities of that region. Data collection was carried out through a semi-structured questionnaire, developed by the researchers themselves, composed of questions aiming to identify the physical rehabilitation centers in the towns, the staff members involved, the provision of assistive technology through SUS, delivery time and existence of waiting lists. Results and discussion: The data were statistically measured, categorized, described and correlated with the current legislation aimed to guarantee access to assistive technology. We observed that the practice around this resource in the 3rd region concentrates in a single care center, causing long waits and poor efficiency of the services provided, in addition to maintaining a paternalistic aspect. Conclusion: This study provides evidence that, although the right to access to assistive technology is legally guaranteed, there are still many difficulties and challenges around this practice.

  6. Patient views on an electronic dispensing device for prepackaged polypharmacy: a qualitative assessment in an ambulatory setting

    Directory of Open Access Journals (Sweden)

    Allemann SS

    2015-11-01

    Full Text Available Samuel S Allemann, Kurt E Hersberger, Isabelle ArnetPharmaceutical Care Research Group, Department of Pharmaceutical Sciences, University of Basel, Basel, SwitzerlandObjective: To collect opinions on medication management aids (MMAs in general and on an electronic MMA (e-MMA dispensing prepackaged polypharmacy in sealed pouches.Study setting: The setting involved community-dwelling older adults in Basel, Switzerland, in 2013.Study design: The study involved 1 a 14-day trial with the e-MMA and 2 a focus group to identify general attributes of MMAs, their applicability to the e-MMA, and possible target groups for the e-MMA.Data collection methods: Six participants using long-term polypharmacy and willing to try new technologies completed the 14-day trial and participated in the focus group. Inductive content analysis was performed to extract data.Principal findings: Participants rated ten of 17 general attributes as clearly applicable to the e-MMA and five as unsuitable. Attributes pertained to three interrelating themes: product design, patient support, and living conditions. Envisaged target groups were patients with time-sensitive medication regimens, patients with dementia, the visually impaired, and several patients living together to prevent accidental intake of the wrong medication.Conclusion: The evaluated e-MMA for prepackaged polypharmacy met the majority of the requirements set for an MMA. Patients' living conditions, such as mobility, remain the key determinants for acceptance of an e-MMA.Keywords: pharmaceutical care, medication adherence, medication management aids, automated drug dispensing

  7. Development of suitable potting material for dispenser cathodes of a high power microwave tube

    International Nuclear Information System (INIS)

    Highlights: ► Potting material. ► Doped alumina. ► Non-shrinkable. ► Dispenser cathode. ► Microwave tube. - Abstract: The present study aims to develop suitable advanced potting material for modern high performance dispenser cathodes for high power microwave tube through refinement of the alumina microstructure by using suitable dopant. Calcium oxide was selected as a dopant material and the resultant materials were characterized by X-ray diffraction studies and the microstructure monitored by SEM study and EDX analysis. The shrinkage, thermal and electrical properties of the resultant material was evaluated to establish its suitability to function as an advanced potting material.

  8. PRELIMINARY INVESTIGATION ON THE BACTERIOLOGICAL QUALITY OF MICROFILTERED DRINKING WATER DISPENSERS IN CATERING ESTABLISHMENTS

    Directory of Open Access Journals (Sweden)

    M.A. Marzano

    2011-04-01

    Full Text Available The bacteriological quality of microfiltered drinking water dispensers was evaluated, through enumeration of heterotrophic plate count at 22 and 37 °C, total coliforms, Escherichia coli, Enterococcus spp. and Pseudomonas aeruginosa. The aim of this research was to control the hygiene of the microfiltered water and to evaluate the effectiveness of the microfiltration procedure on the survival of bacteria. In total, 54 water samples were analyzed. The results indicated a high contamination frequency with P. aeruginosa (25 and 20% in room temperature and chilled water samples, respectively and therefore the need to improve the efficacy and the frequency of the dispenser sanitation procedures.

  9. Flat acoustic lens by acoustic grating with curled slits

    Energy Technology Data Exchange (ETDEWEB)

    Peng, Pai; Xiao, Bingmu; Wu, Ying, E-mail: ying.wu@kaust.edu.sa

    2014-10-03

    We design a flat sub-wavelength lens that can focus acoustic wave. We analytically study the transmission through an acoustic grating with curled slits, which can serve as a material with tunable impedance and refractive index for acoustic waves. The effective parameters rely on the geometry of the slits and are independent of frequency. A flat acoustic focusing lens by such acoustic grating with gradient effective refractive index is designed. The focusing effect is clearly observed in simulations and well predicted by the theory. We demonstrate that despite the large impedance mismatch between the acoustic lens and the matrix, the intensity at the focal point is still high due to Fabry–Perot resonance. - Highlights: • Expression of transmission coefficient of an acoustic grating with curled slits. • Non-dispersive and tunable effective medium parameters for the acoustic grating. • A flat acoustic focusing lens with gradient index by using the acoustic grating.

  10. The Technology of Vibration and Acoustics Reduction in Home Refrigerator%家用冰箱减振降噪技术

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

      为了降低冰箱噪声,进一步减少冰箱、尤其是压缩机在工作中的噪声辐射能量,本文介绍了常用的几种减振降噪技术:声源分析、防止共振、隔离技术、阻尼技术和材料、有源降噪和吸声材料。试验证实,采用阻尼技术和吸声材料,冰箱整机噪声可降低3~5dB(A),这表明,上述降噪技术在冰箱的降噪过程中是行之有效的方法。%Several vibration and noise reduction technology of refrigerator were introduced to reduce re-frigerator noise, as well as refrigerator compressor’s radiation efficiency, such as noise analysis, resonance a-voidance, partial enclosures, damp technology and materials, active noise reduction and sound absorbing ma-terials. It is proved that 3 to 5dB (A) can be reduced with damp technology and sound absorbing materials. Results show that the vibration and noise reduction technology above-mentioned are useful methods to reduce re-frigerator noise.

  11. From Architectural Acoustics to Acoustical Architecture Using Computer Simulation

    OpenAIRE

    Schmidt, Anne Marie Due; KIRKEGAARD, Poul Henning

    2005-01-01

    Architectural acoustics design has in the past been based on simple design rules. However, with a growing complexity in architectural acoustics and the emergence of room acoustic simulation programmes with considerable potential, it is now possible to subjectively analyse and evaluate acoustic properties prior to the actual construction of a building. With the right tools applied, acoustic design can become an integral part of the architectural design process. The aim of this paper is to inve...

  12. Peptide synthesis on glass substrate using acoustic droplet ejector.

    Science.gov (United States)

    Youngki Choe; Shih-Jui Chen; Eun Sok Kim

    2014-03-01

    This paper describes the synthesis of a 9-mers-long peptide ladder structure of glycine on a modified glass surface using a nanoliter droplet ejector. To synthesize peptide on a glass substrate, SPOT peptide synthesis protocol was followed with a nozzleless acoustic droplet ejector being used to eject about 300 droplets of preactivated amino acid solution to dispense 60 nL of the solution per mer. The coupling efficiency of each mer was measured with FITC fluorescent tag to be 96%, resulting in net 70% efficiency for the whole 9-mer-long peptide of glycine. Usage of a nanoliter droplet ejector for SPOT peptide synthesis increases the density of protein array on a chip. PMID:24235271

  13. An overview of acoustic telemetry

    Energy Technology Data Exchange (ETDEWEB)

    Drumheller, D.S.

    1992-01-01

    Acoustic telemetry has been a dream of the drilling industry for the past 50 years. It offers the promise of data rates which are one-hundred times greater than existing technology. Such a system would open the door to true logging-while-drilling technology and bring enormous profits to its developers. The basic idea is to produce an encoded sound wave at the bottom of the well, let it propagate up the steel drillpipe, and extract the data from the signal at the surface. Unfortunately, substantial difficulties arise. The first difficult problem is to produce the sound wave. Since the most promising transmission wavelengths are about 20 feet, normal transducer efficiencies are quire low. Compounding this problem is the structural complexity of the bottomhole assembly and drillstring. For example, the acoustic impedance of the drillstring changes every 30 feet and produces an unusual scattering pattern in the acoustic transmission. This scattering pattern causes distortion of the signal and is often confused with signal attenuation. These problems are not intractable. Recent work has demonstrated that broad frequency bands exist which are capable of transmitting data at rates up to 100 bits per second. Our work has also identified the mechanism which is responsible for the observed anomalies in the patterns of signal attenuation. Furthermore in the past few years a body of experience has been developed in designing more efficient transducers for application to metal waveguides. The direction of future work is clear. New transducer designs which are more efficient and compatible with existing downhole power supplies need to be built and tested; existing field test data need to be analyzed for transmission bandwidth and attenuation; and the new and less expensive methods of collecting data on transmission path quality need to be incorporated into this effort. 11 refs.

  14. Dispensação farmacêutica: proposta de um modelo para a prática Dispensation of pharmaceuticals: proposal of a model for dispensation

    Directory of Open Access Journals (Sweden)

    Daniela Angonesi

    2011-09-01

    Full Text Available A dispensação é uma atividade farmacêutica que não pode se restringir apenas à entrega do medicamento. O farmacêutico deve promover as condições para que o paciente faça uso do medicamento da melhor maneira possível. Como se trata de uma atividade profissional, e assim como foi estabelecido para a atenção farmacêutica, a dispensação também deve possuir uma filosofia de prática, um processo de cuidado e um sistema de gestão da prática. Este trabalho propõe uma nova definição de dispensação e descreve os seus elementos centrais considerando a realidade dos estabelecimentos farmacêuticos de forma que possa efetivamente ser implementada.The dispensation of pharmaceuticals is an activity that cannot be restricted only to the delivery of medication. The pharmacist must ensure various conditions to ensure that the patient uses the medication in the best possible manner. As it is a professional activity and has been established for pharmaceutical care, dispensation should also have a philosophy of practice, a process of care, and a system for managing the practice. This paper proposes a new definition of dispensation and describes its central elements, considering the reality of established pharmacists, so that it can be effectively implemented.

  15. Assessing the optimal location for alcohol-based hand rub dispensers in a patient room in an intensive care unit

    NARCIS (Netherlands)

    Boog, M.C.; Erasmus, V.; De Graaf, J.M.; Van Beeck, E.H.E.; Melles, M.; Van Beeck, E.F.

    2013-01-01

    Background The introduction of alcohol-based hand rub dispensers has had a positive influence on compliance of healthcare workers with the recommended guidelines for hand hygiene. However, establishing the best location for alcohol-based hand rub dispensers remains a problem, and no method is curren

  16. Underwater Applications of Acoustical Holography

    Directory of Open Access Journals (Sweden)

    P. C. Mehta

    1984-01-01

    Full Text Available The paper describes the basic technique of acoustical holography. Requirements for recording the acoustical hologram are discussed with its ability for underwater imaging in view. Some practical systems for short-range and medium-range imaging are described. The advantages of acoustical holography over optical imaging, acoustical imaging and sonars are outlined.

  17. Acoustic Resonator Optimisation for Airborne Particle Manipulation

    Science.gov (United States)

    Devendran, Citsabehsan; Billson, Duncan R.; Hutchins, David A.; Alan, Tuncay; Neild, Adrian

    Advances in micro-electromechanical systems (MEMS) technology and biomedical research necessitate micro-machined manipulators to capture, handle and position delicate micron-sized particles. To this end, a parallel plate acoustic resonator system has been investigated for the purposes of manipulation and entrapment of micron sized particles in air. Numerical and finite element modelling was performed to optimise the design of the layered acoustic resonator. To obtain an optimised resonator design, careful considerations of the effect of thickness and material properties are required. Furthermore, the effect of acoustic attenuation which is dependent on frequency is also considered within this study, leading to an optimum operational frequency range. Finally, experimental results demonstrated good particle levitation and capture of various particle properties and sizes ranging to as small as 14.8 μm.

  18. Ocean acoustic reverberation tomography.

    Science.gov (United States)

    Dunn, Robert A

    2015-12-01

    Seismic wide-angle imaging using ship-towed acoustic sources and networks of ocean bottom seismographs is a common technique for exploring earth structure beneath the oceans. In these studies, the recorded data are dominated by acoustic waves propagating as reverberations in the water column. For surveys with a small receiver spacing (e.g., tomography, is developed that uses the travel times of direct and reflected waves to image ocean acoustic structure. Reverberation tomography offers an alternative approach for determining the structure of the oceans and advancing the understanding of ocean heat content and mixing processes. The technique has the potential for revealing small-scale ocean thermal structure over the entire vertical height of the water column and along long survey profiles or across three-dimensional volumes of the ocean. For realistic experimental geometries and data noise levels, the method can produce images of ocean sound speed on a smaller scale than traditional acoustic tomography. PMID:26723303

  19. Acoustic integrated extinction

    CERN Document Server

    Norris, Andrew N

    2015-01-01

    The integrated extinction (IE) is defined as the integral of the scattering cross-section as a function of wavelength. Sohl et al. [1] derived an IE expression for acoustic scattering that is causal, i.e. the scattered wavefront in the forward direction arrives later than the incident plane wave in the background medium. The IE formula was based on electromagnetic results, for which scattering is causal by default. Here we derive a formula for the acoustic IE that is valid for causal and non-causal scattering. The general result is expressed as an integral of the time dependent forward scattering function. The IE reduces to a finite integral for scatterers with zero long-wavelength monopole and dipole amplitudes. Implications for acoustic cloaking are discussed and a new metric is proposed for broadband acoustic transparency.

  20. Autonomous Acoustic Receiver System

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Collects underwater acoustic data and oceanographic data. Data are recorded onboard an ocean buoy and can be telemetered to a remote ship or shore station...

  1. Thermal Acoustic Fatigue Apparatus

    Data.gov (United States)

    Federal Laboratory Consortium — The Thermal Acoustic Fatigue Apparatus (TAFA) is a progressive wave tube test facility that is used to test structures for dynamic response and sonic fatigue due to...

  2. Acoustic Igniter Project

    Data.gov (United States)

    National Aeronautics and Space Administration — An acoustic igniter eliminates the need to use electrical energy to drive spark systems to initiate combustion in liquid-propellant rockets. It does not involve the...

  3. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... treatment Summary Types Of Post-treatment Issues Resources Medical Resources Considerations When Selecting a Healthcare Professional Healthcare ... ANA? Mission Statement Board of Directors ANA Staff Medical Advisory Board News ANA Annual Reports Acoustic Neuroma ...

  4. Acoustics lecturing in Mexico

    Science.gov (United States)

    Beristain, Sergio

    2002-11-01

    Some thirty years ago acoustics lecturing started in Mexico at the National Polytechnic Institute in Mexico City, as part of the Bachelor of Science degree in Communications and Electronics Engineering curricula, including the widest program on this field in the whole country. This program has been producing acoustics specialists ever since. Nowadays many universities and superior education institutions around the country are teaching students at the B.Sc. level and postgraduate level many topics related to acoustics, such as Architectural Acoustics, Seismology, Mechanical Vibrations, Noise Control, Audio, Audiology, Music, etc. Also many institutions have started research programs in related fields, with participation of medical doctors, psychologists, musicians, engineers, etc. Details will be given on particular topics and development.

  5. An acoustic invisible gateway

    CERN Document Server

    Zhu, Yi-Fan; Liang, Bin; Kan, Wei-Wei; Yang, Jun; Cheng, Jian-Chun

    2015-01-01

    The recently-emerged concept of "invisible gateway" with the extraordinary capability to block the waves but allow the passage of other entities has attracted great attentions due to the general interests in illusion devices. However, the possibility to realize such a fascinating phenomenon for acoustic waves has not yet been explored, which should be of paramount significance for acoustical applications but would necessarily involve experimental difficulty. Here we design and experimentally demonstrate an acoustic invisible gateway (AIG) capable of concealing a channel under the detection of sound. Instead of "restoring" a whole block of background medium by using transformation acoustics that inevitably requires complementary or restoring media with extreme parameters, we propose an inherently distinct methodology that only aims at engineering the surface impedance at the "gate" to mimic a rigid "wall" and can be conveniently implemented by decorating meta-structures behind the channel. Such a simple yet ef...

  6. Anal acoustic reflectometry

    DEFF Research Database (Denmark)

    Mitchell, Peter J; Klarskov, Niels; Telford, Karen J;

    2011-01-01

    Anal acoustic reflectometry is a new technique of assessing anal sphincter function. Five new variables reflecting anal canal function are measured: the opening and closing pressure, the opening and closing elastance, and hysteresis.......Anal acoustic reflectometry is a new technique of assessing anal sphincter function. Five new variables reflecting anal canal function are measured: the opening and closing pressure, the opening and closing elastance, and hysteresis....

  7. Acoustic surface cavitation

    OpenAIRE

    Zijlstra, Aaldert Geert

    2011-01-01

    Merely the presence of compressible entities, known as bubbles, greatly enriches the physical phenomena encountered when introducing ultrasound in a liquid. Mediated by the response of these bubbles, the otherwise diffuse and relatively low energy density of the acoustic field can induce strong, localized liquid motion, high internal temperatures and pressures as well as secondary acoustic emissions. In turn, these effects give rise to considerable stresses exerted on nearby objects and molec...

  8. Wavefront modulation and subwavelength diffractive acoustics with an acoustic metasurface.

    Science.gov (United States)

    Xie, Yangbo; Wang, Wenqi; Chen, Huanyang; Konneker, Adam; Popa, Bogdan-Ioan; Cummer, Steven A

    2014-01-01

    Metasurfaces are a family of novel wavefront-shaping devices with planar profile and subwavelength thickness. Acoustic metasurfaces with ultralow profile yet extraordinary wave manipulating properties would be highly desirable for improving the performance of many acoustic wave-based applications. However, designing acoustic metasurfaces with similar functionality to their electromagnetic counterparts remains challenging with traditional metamaterial design approaches. Here we present a design and realization of an acoustic metasurface based on tapered labyrinthine metamaterials. The demonstrated metasurface can not only steer an acoustic beam as expected from the generalized Snell's law, but also exhibits various unique properties such as conversion from propagating wave to surface mode, extraordinary beam-steering and apparent negative refraction through higher-order diffraction. Such designer acoustic metasurfaces provide a new design methodology for acoustic signal modulation devices and may be useful for applications such as acoustic imaging, beam steering, ultrasound lens design and acoustic surface wave-based applications. PMID:25418084

  9. Assessment of informatization for the dispensing of medications at a university hospital

    Directory of Open Access Journals (Sweden)

    Sônia Aparecida Dias Serafim

    2010-01-01

    Full Text Available INTRODUCTION: Informatics and automation are important tools for the reduction of work, errors and costs in a hospital pharmacy. OBJECTIVES: To describe the structuring and function of an informatized system for the dispensing of medications and to assess its effect on nursing and pharmacy services during the period from 1997 to 2003. MATERIALS AND METHODS: In this descriptive and retrospective study, we performed an analysis of documents addressing the structuring and implementation of the informatized medication dispensing system. In addition, we analyzed the perceptions of nurses, pharmacists and pharmacy assistants who participated in the structuring phase of the system when interviewed about the effect of informatization on administrative aspects (e.g., requisition of medications, presentation of the dispensed medication and system operationalization. RESULTS: The major advantages provided by the new system were 1 the elimination of manual transcripts for prescribed medications, 2 increased speed, 3 better identification of the doses prescribed by physicians, 4 medication labels containing all necessary identification and 5 practicality and safety of optical bar code-based verification of the requested and dispensed medications. CONCLUSIONS: The great majority of the interviewees considered the informatized medication supply system to be of good quality. Analysis of the data provided information that could contribute to the expansion and refinement of the system, provide support for studies regarding the utilization of medications and offer new perspectives for work and productivity.

  10. 29 CFR 801.13 - Exemption of employers authorized to manufacture, distribute, or dispense controlled substances.

    Science.gov (United States)

    2010-07-01

    ... (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION OF THE EMPLOYEE POLYGRAPH... regarding the use of polygraph tests for employers authorized to manufacture, distribute, or dispense a... U.S.C. 812). This exemption permits the administration of polygraph tests, subject to the...

  11. Efficacy of a Feed Dispenser for Horses in Decreasing Cribbing Behaviour

    Directory of Open Access Journals (Sweden)

    Silvia Mazzola

    2016-01-01

    Full Text Available Cribbing is an oral stereotypy, tends to develop in captive animals as a means to cope with stress, and may be indicative of reduced welfare. Highly energetic diets ingested in a short time are one of the most relevant risk factors for the development of cribbing. The aim of this study was to verify whether feeding cribbing horses through a dispenser that delivers small quantities of concentrate when activated by the animal decreases cribbing behaviour, modifies feeding behaviour, or induces frustration. Ten horses (mean age 14 y, balanced for sex, breed, and size (mean height 162 cm, were divided into two groups of 5 horses each: Cribbing and Control. Animals were trained to use the dispenser and videorecorded continuously for 15 consecutive days from 1 h prior to feeding to 2 h after feeding in order to measure their behaviours. The feed dispenser, Quaryka®, induced an increase in time necessary to finish the ration in both groups of horses (P<0.05. With Quaryka, cribbers showed a significant reduction of time spent cribbing (P<0.05. After removal of the feed dispenser (Post-Quaryka, cribbing behaviour significantly increased. The use of Quaryka may be particularly beneficial in horses fed high-energy diets and ingesting the food too quickly.

  12. MICROBIO : A web-based program for processing and evaluation of microbiological controls on aseptic dispensing

    NARCIS (Netherlands)

    Postma, D.J.; Boom, F.A.; Bijleveld, Y.A.; Touw, D.J.; Veenbaas, T.; Essink-Tjebbes, C.M.; Verbrugge, P.

    2012-01-01

    Background: According to the Dutch GMP-hospital pharmacy directive (1) three types of microbiological controls are required when aseptic dispensing is performed: 1. microbiological monitoring of the air in the working area, the gloved hands of the operator and the work surface at the critical place

  13. A systematic approach for the location of hand sanitizer dispensers in hospitals.

    Science.gov (United States)

    Cure, Laila; Van Enk, Richard; Tiong, Ewing

    2014-09-01

    Compliance with hand hygiene practices is directly affected by the accessibility and availability of cleaning agents. Nevertheless, the decision of where to locate these dispensers is often not explicitly or fully addressed in the literature. In this paper, we study the problem of selecting the locations to install alcohol-based hand sanitizer dispensers throughout a hospital unit as an indirect approach to maximize compliance with hand hygiene practices. We investigate the relevant criteria in selecting dispenser locations that promote hand hygiene compliance, propose metrics for the evaluation of various location configurations, and formulate a dispenser location optimization model that systematically incorporates such criteria. A complete methodology to collect data and obtain the model parameters is described. We illustrate the proposed approach using data from a general care unit at a collaborating hospital. A cost analysis was performed to study the trade-offs between usability and cost. The proposed methodology can help in evaluating the current location configuration, determining the need for change, and establishing the best possible configuration. It can be adapted to incorporate alternative metrics, tailored to different institutions and updated as needed with new internal policies or safety regulation. PMID:24194381

  14. Close up of the glue dispenser. The white lines on the green frames are theapplied glue.

    CERN Multimedia

    Bernd Surrow

    1999-01-01

    The gantry motion control along with the pneumatic glue dispenser system allows precise control of the amount of glue applied to theframe. The glue is a special room temperature cure silicone basedglue chosen to minimize surface stresses on the silicon sensors dueto differential temperature contraction.

  15. Rac1 in muscle is dispensable for improved insulin action after exercise in mice

    DEFF Research Database (Denmark)

    Sylow, Lykke; Møller, Lisbeth Liliendal Valbjørn; D'Hulst, Gommaar;

    2016-01-01

    significantly improved insulin sensitivity by 20% in WT and by 40% in Rac1 mKO soleus muscles. These findings suggest that muscle Rac1 is dispensable for the insulin sensitizing effect of exercise. Moreover, insulin resistance in Rac1 mKO mice can be completely normalized by prior exercise explaining why...

  16. Root Cause Analysis of Water Wastage in Hot - Cold Water Dispenser

    Directory of Open Access Journals (Sweden)

    Sunil Kokane

    2015-03-01

    Full Text Available Hot - Cold Water Dispenser is a high end kitchen product mounted on sink of kitchen to meet the requirement of instant hot and cold water as desired. It provides cold water at ambient temperature and hot water at near boiling temperature of about 97ºC to meet the instant water need. It was reported from few users, small amount of unnecessary water get dispensed from the Hot - Cold Water Dispenser during the idle conditions. This is undesirable and affecting on the overall performance of product. This paper briefs the available Root Cause Analysis and process to select the suitable method to find out the root cause of problem. From the available methods, Fault Tree Analysis was found to be most suitable method. The paper describes this method in length. Fault Tree Analysis is used as the scientific approach to find the root cause of problem of water dripping in Hot - Cold Water Dispenser at idle condition. It makes use of a graphical representation of the major faults associated with the product, the causes for the faults, and potential countermeasures. It is found that the FTA tool helps to identify areas of concern for new product design as well as for improvement of existing products.

  17. Ultrasound aided smooth dispensing for high viscoelastic epoxy in microelectronic packaging.

    Science.gov (United States)

    Chen, Yun; Li, Han-Xiong; Shan, Xiuyang; Gao, Jian; Chen, Xin; Wang, Fuliang

    2016-01-01

    Epoxy dispensing is one of the most critical processes in microelectronic packaging. However, due its high viscoelasticity, dispensing of epoxy is extremely difficult, and a lower viscoelasticity epoxy is desired to improve the process. In this paper, a novel method is proposed to achieve a lowered viscoelastic epoxy by using ultrasound. The viscoelasticity and molecular structures of the epoxies were compared and analyzed before and after experimentation. Different factors of the ultrasonic process, including power, processing time and ultrasonic energy, were studied in this study. It is found that elasticity is more sensitive to ultrasonic processing while viscosity is little affected. Further, large power and long processing time can minimize the viscoelasticity to ideal values. Due to the reduced loss modulus and storage modulus after ultrasonic processing, smooth dispensing is demonstrated for the processed epoxy. The subsequently color temperature experiments show that ultrasonic processing will not affect LED's lighting. It is clear that the ultrasonic processing will have good potential to aide smooth dispensing for high viscoelastic epoxy in electronic industry. PMID:26384878

  18. 21 CFR 1306.07 - Administering or dispensing of narcotic drugs.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Administering or dispensing of narcotic drugs. 1306.07 Section 1306.07 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE... an incidental adjunct to medical or surgical treatment of conditions other than addiction, or...

  19. Container with heat or cold dispensing material comprising hydrogel with crosslinked hydrophilic polymer

    NARCIS (Netherlands)

    Van Turnhout, J.

    2000-01-01

    PCT No. PCT/NL97/00102 Sec. 371 Date Oct. 20, 1998 Sec. 102(e) Date Oct. 20, 1998 PCT Filed Mar. 3, 1997 PCT Pub. No. WO97/33950 PCT Pub. Date Sep. 18, 1997A device for storing and gradually dispensing heat or cold includes a container having a partially heat-conducting wall enclosing a space with m

  20. 21 CFR 866.2440 - Automated medium dispensing and stacking device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Automated medium dispensing and stacking device. 866.2440 Section 866.2440 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES IMMUNOLOGY AND MICROBIOLOGY DEVICES Microbiology Devices §...

  1. The knowledge of emergency contraception and dispensing practices of Patent Medicine Vendors in South West Nigeria.

    Science.gov (United States)

    Fayemi, Mojisola M; Oduola, Olufemi L; Ogbuji, Queen C; Osinowo, Kehinde A; Oyewo, Adejoke E; Osiberu, Olabimpe M

    2010-09-01

    Patent Medicine Vendors (PMVs) can play a critical role in increasing access to emergency contraceptive pills (ECPs) in developing countries, but few studies have examined their knowledge and dispensing practices. Using cluster sampling, the authors selected and interviewed 97 PMVs (60.8 per cent female) in Oyo and Ogun States of Nigeria to assess their knowledge, dispensing practices, and referral for ECPs. About one-third (27.8 per cent) of respondents were not aware of ECPs, and only half knew that ECPs could prevent pregnancy. Forty per cent had ever dispensed ECPs. Reasons proffered by those who do not dispense ECPs included barriers from the State Ministry of Health, police, other regulatory agencies, and religious beliefs. Only 50.5 per cent have referral arrangements for clients. Strategies to increase access to ECPs through PMVs include training on counseling techniques and referral, effective government regulation, and community involvement. Where unsafe abortion is a major cause of maternal mortality, these strategies offer protection for many women in the future. PMID:20805800

  2. 30 CFR 57.4262 - Underground transformer stations, combustible liquid storage and dispensing areas, pump rooms...

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Underground transformer stations, combustible... and Control Firefighting Equipment § 57.4262 Underground transformer stations, combustible liquid storage and dispensing areas, pump rooms, compressor rooms, and hoist rooms. Transformer stations,...

  3. Acoustics and the Performance of Music Manual for Acousticians, Audio Engineers, Musicians, Architects and Musical Instrument Makers

    CERN Document Server

    Meyer, Jürgen

    2009-01-01

    Acoustics and the Performance of Music connects scientific understandings of acoustics with practical applications to musical performance. Of central importance are the tonal characteristics of musical instruments and the singing voice including detailed representations of directional characteristics. Furthermore, room acoustical concerns related to concert halls and opera houses are considered. Based on this, suggestions are made for musical performance. Included are seating arrangements within the orchestra and adaptations of performance techniques to the performance environment. In the presentation we dispense with complicated mathematical connections and deliberately aim for conceptual explanations accessible to musicians, particularly for conductors. The graphical representations of the directional dependence of sound radiation by musical instruments and the singing voice are unique. Since the first edition was published in 1978, this book has been completely revised and rewritten to include current rese...

  4. Control of bacterial contamination in microfiltered water dispensers (MWDs) by disinfection.

    Science.gov (United States)

    Zanetti, Franca; De Luca, Giovanna; Sacchetti, Rossella

    2009-01-15

    Three microfiltered water dispensers (MWDs) for domestic use were bacteriologically monitored over a period of 1 year to evaluate their hygienic status and to compare the ability of two disinfectants (peracetic acid and hydrogen peroxide) to ensure adequate bacteriological quality of the dispensed water. To this end, two dispensers were purposely contaminated with a strain of Pseudomonas aeruginosa of environmental origin. A total of 324 samples of input and output water were analyzed. Heterotrophic plate count (HPC) bacteria at 22 degrees C and 36 degrees C, total coliforms (CT), Escherichia coli (EC), enterococci (ENT), P. aeruginosa and Staphylococcus aureus were enumerated. Throughout the study period, the supply water was always of excellent bacteriological quality. All water samples taken from the MWDs complied with the legal requirements for drinking water: CT, EC, ENT and S. aureus were all consistently absent. P. aeruginosa was never isolated from the uncontaminated dispenser. However, an increase in HPCs up to levels of 10(3)-10(4) cfu/mL was found in the dispensed water. Under the present operative conditions, hydrogen peroxide was seen to be more effective than peracetic acid in controlling bacterial contamination in the water circuits. Periodic disinfection with hydrogen peroxide made it possible to obtain water with HPC levels conforming to Italian regulations for drinking water (disinfection led to a reduction in the concentrations of P. aeruginosa to only a few colony forming units/100 mL or to a complete, albeit temporary, disappearance of the microorganism. In conclusion, hydrogen peroxide at 3% can be proposed as a suitable product for periodic disinfection of domestic MWDs, taking into consideration also its low cost and easy availability.

  5. Piezo dispensed microarray of multivalent chelating thiols for dissecting complex protein-protein interactions.

    Science.gov (United States)

    Klenkar, Goran; Valiokas, Ramûnas; Lundström, Ingemar; Tinazli, Ali; Tampé, Robert; Piehler, Jacob; Liedberg, Bo

    2006-06-01

    The fabrication of a novel biochip, designed for dissection of multiprotein complex formation, is reported. An array of metal chelators has been produced by piezo dispensing of a bis-nitrilotriacetic acid (bis-NTA) thiol on evaporated gold thin films, prestructured with a microcontact printed grid of eicosanethiols. The bis-NTA thiol is mixed in various proportions with an inert, tri(ethylene glycol) hexadecane thiol, and the thickness and morphological homogeneity of the dispensed layers are characterized by imaging ellipsometry before and after back-filling with the same inert thiol and subsequent rinsing. It is found that the dispensed areas display a monotonic increase in thickness with increasing molar fraction of bis-NTA in the dispensing solution, and they are consistently a few Angströms thicker than those prepared at the same molar fraction by solution self-assembly under equilibrium-like conditions. The bulkiness of the bis-NTA tail group and the short period of time available for chemisorption and in-plane organization of the dispensed thiols are most likely responsible for the observed difference in thickness. Moreover, the functional properties of this biochip are demonstrated by studying multiple protein-protein interactions using imaging surface plasmon resonance. The subunits of the type I interferon receptor are immobilized as a composition array determined by the surface concentration of bis-NTA in the array elements. Ligand dissociation kinetics depends on the receptor surface concentration, which is ascribed to the formation of a ternary complex by simultaneous interaction of the ligand with the two receptor subunits. Thus, multiplexed monitoring of binding phenomena at various compositions (receptor densities) offers a powerful tool to dissect protein-protein interactions.

  6. Investigation and improvement of the dispenser printing of electrical interconnections for smart fabric applications

    Science.gov (United States)

    Ahmed, Z.; Torah, R.; Yang, K.; Beeby, S.; Tudor, J.

    2016-10-01

    Electrical interconnections are essential for the integration of electronic functions in a fabric. These interconnects can be dispenser printed on a fabric; however printing directly on a breathable woven fabric surface is challenging due to the high surface variation and porosity defined by the weave. This paper, for the first time, experimentally shows that fabric surface variation leads to inconsistent printed structures which adversely affects the electrical properties of printed conductive tracks. It investigates a solution of overcoming the fabric surface variation in the form of dispenser printing an interface layer between the conductive ink and the fabric surface. Four dielectric inks DuPont 5018, Electra EFV4/4965, Fabinks-UV-IF-1004 and Fabinks-UV-TC0233 are quantitatively evaluated, as interface materials, in terms of surface consistency, thickness consistency, repeatability, flexibility, thermal stability and the electrical characteristics of conductive tracks printed on them. All four of the evaluated interface materials significantly reduced the fabric surface variation by more than 95% and provided a suitable low variation surface for printing subsequent electronic layers. Conductive tracks, dispenser printed on the four interface materials, produced ∼90% lower electrical resistivity compared to tracks printed directly on the fabric and similar resistivity to dispenser printed tracks on Kapton, a traditional printed electronic substrate. An increased focus on low powered electronics especially for wearables requires the electrical interconnections to dissipate minimum power. The innovative interface layer approach allows fabrication of low resistance electrical interconnections on fabric substrates reducing interconnect power dissipation, making this approach highly suitable for smart fabric applications. Reported details of dispenser printing of interface materials can be used for replicating these results on a range of fabric substrates. The

  7. Frequency, types, and potential clinical significance of medication-dispensing errors

    Directory of Open Access Journals (Sweden)

    Xavier Bohand

    2009-01-01

    Full Text Available INTRODUCTION AND OBJECTIVES: Many dispensing errors occur in the hospital, and these can endanger patients. The purpose of this study was to assess the rate of dispensing errors by a unit dose drug dispensing system, to categorize the most frequent types of errors, and to evaluate their potential clinical significance. METHODS: A prospective study using a direct observation method to detect medication-dispensing errors was used. From March 2007 to April 2007, "errors detected by pharmacists" and "errors detected by nurses" were recorded under six categories: unauthorized drug, incorrect form of drug, improper dose, omission, incorrect time, and deteriorated drug errors. The potential clinical significance of the "errors detected by nurses" was evaluated. RESULTS: Among the 734 filled medication cassettes, 179 errors were detected corresponding to a total of 7249 correctly fulfilled and omitted unit doses. An overall error rate of 2.5% was found. Errors detected by pharmacists and nurses represented 155 (86.6% and 24 (13.4% of the 179 errors, respectively. The most frequent types of errors were improper dose (n = 57, 31.8% and omission (n = 54, 30.2%. Nearly 45% of the 24 errors detected by nurses had the potential to cause a significant (n = 7, 29.2% or serious (n = 4, 16.6% adverse drug event. CONCLUSIONS: Even if none of the errors reached the patients in this study, a 2.5% error rate indicates the need for improving the unit dose drug-dispensing system. Furthermore, it is almost certain that this study failed to detect some medication errors, further arguing for strategies to prevent their recurrence.

  8. International Space Station USOS Potable Water Dispenser On-Orbit Functionality Versus Design

    Science.gov (United States)

    Toon, Katherine P.; Lovell, Randal W.

    2010-01-01

    The International Space Station (ISS) currently provides potable water dispensing for rehydrating crewmember food and drinking packages. There is one system located in the United States On-orbit Segment (USOS) and one system in the Russian Segment. Shuttle mission STS-126 delivered the USOS Potable Water Dispenser (PWD) to ISS on ULF2; subsequent activation occurred on November 2008. The PWD is capable of supporting an ISS crew of six, but nominally supplies only half this crew size. The PWD design provides incremental quantities of hot and ambient temperature potable water to US food and beverage packages. PWD receives iodinated water from the US Water Recovery System (WRS) Fuel Cell Water Bus, which feeds from the Water Processing Assembly (WPA). The PWD removes the biocidal iodine to make the water potable prior to dispensing. A heater assembly contained within the unit supplies up to 2.0 L of hot water (65 to 93 ?C) every 30 min. During a single meal, this quantity of water supports three to four crewmembers? food rehydration and beverages. The unit design has a functional life expectancy of 10 years, with replacement of limited life items, such as filters. To date, the PWD on-orbit performance is acceptable. Since activation of the PWD, there were several differences between on-orbit functionality and expected performance of hardware design. The comparison of on-orbit functionality to performance of hardware design is discussed for the following key areas: 1) microbial contamination, 2) no-dispense and water leakage scenarios, and 3) under-dispense scenarios.

  9. International Space Station USOS Potable Water Dispenser On-Orbit Functionality vs Design

    Science.gov (United States)

    Toon, Katherine P.; Lovell, Randal W.

    2009-01-01

    The International Space Station (ISS) currently provides potable water dispensing for rehydrating crewmembers food and drinking packages with one system located in the United States On-orbit Segment (USOS) and one system in the Russian Segment. The USOS Potable Water Dispenser (PWD) was delivered to ISS on ULF2, Shuttle Mission STS-126, and was subsequently activated in November 2008. The PWD activation on ISS is capable of supporting an ISS crew of six but nominally supplies only half the crew. The PWD is designed to provide incremental quantities of hot and ambient temperature potable water to US style food packages. PWD receives iodinated water from the US Laboratory Fuel Cell Water Bus, which is fed from the Water Processing Assembly (WPA). The PWD removes the biocidal iodine to make the water potable prior to dispensing. A heater assembly contained within the unit supplies up to 2.0 liters of hot water (65 to 93oC) every thirty minutes. This quantity supports three to four crewmembers to rehydrate their food and beverages from this location during a single meal. The unit is designed to remain functional for up to ten years with replacement of limited life items such as filters. To date, the PWD on-orbit performance has been acceptable. Since activation of the PWD, there have been several differences between on-orbit functionality and expected performance of hardware design. The comparison of on-orbit functionality to performance of hardware design is outlined for the following key areas: microbiology, PWD to food package water leakage, no-dispense scenarios, under-dispense scenarios, and crewmember feedback on actual on-orbit use.

  10. THE INFLUENCE OF WAVE PATTERNS AND FREQUENCY ON THERMO-ACOUSTIC COOLING EFFECT

    Directory of Open Access Journals (Sweden)

    CHEN BAIMAN

    2011-06-01

    Full Text Available With the increasing environmental challenges, the search for an environmentally benign cooling technology that has simple and robust architecture continues. Thermo-acoustic refrigeration seems to be a promising candidate to fulfil these requirements. In this study, a simple thermo-acoustic refrigeration system was fabricated and tested. The thermo-acoustic refrigerator consists of acoustic driver (loudspeaker, resonator, stack, vacuum system and testing system. The effect of wave patterns and frequency on thermo-acoustic cooling effect was studied. It was found that a square wave pattern would yield superior cooling effects compared to other wave patterns tested.

  11. Feature based passive acoustic detection of underwater threats

    Science.gov (United States)

    Stolkin, Rustam; Sutin, Alexander; Radhakrishnan, Sreeram; Bruno, Michael; Fullerton, Brian; Ekimov, Alexander; Raftery, Michael

    2006-05-01

    Stevens Institute of Technology is performing research aimed at determining the acoustical parameters that are necessary for detecting and classifying underwater threats. This paper specifically addresses the problems of passive acoustic detection of small targets in noisy urban river and harbor environments. We describe experiments to determine the acoustic signatures of these threats and the background acoustic noise. Based on these measurements, we present an algorithm for robustly discriminating threat presence from severe acoustic background noise. Measurements of the target's acoustic radiation signal were conducted in the Hudson River. The acoustic noise in the Hudson River was also recorded for various environmental conditions. A useful discriminating feature can be extracted from the acoustic signal of the threat, calculated by detecting packets of multi-spectral high frequency sound which occur repetitively at low frequency intervals. We use experimental data to show how the feature varies with range between the sensor and the detected underwater threat. We also estimate the effective detection range by evaluating this feature for hydrophone signals, recorded in the river both with and without threat presence.

  12. Control of Pseudomonas aeruginosa and Stenotrophomonas maltophilia contamination of microfiltered water dispensers with peracetic acid and hydrogen peroxide.

    Science.gov (United States)

    Sacchetti, Rossella; De Luca, Giovanna; Zanetti, Franca

    2009-06-30

    The abilities of peracetic acid and hydrogen peroxide to remove or reduce Pseudomonas aeruginosa and Stenotrophomonas maltophilia in output water from microfiltered water dispensers (MWDs) were investigated. Two MWDs were inoculated with strains of P. aeruginosa and S. maltophilia isolated from water. Dispensers A and B were disinfected with 10% (v/v) peracetic acid (PAA) and 3% (v/v) hydrogen peroxide (HP) respectively. Each dispenser was disinfected three times at monthly intervals with contact times of 10, 30 and 40 min. Water dispensed by the MWDs was collected immediately before and after each treatment and then twice weekly for the remaining period. Once a week a sample of the tap water entering the dispensers was tested. P. aeruginosa and S. maltophilia were enumerated in the 90 samples collected during 6 months. In the output water from the dispensers before the first treatment, the number of the bacteria was 3 to 4 log cfu/100 mL. Treatment with PAA greatly reduced the numbers of P. aeruginosa and S. maltophilia in the dispensed water initially. However, by 2 days after treatment, the numbers increased and remained high. In the case of disinfection with HP for 40 min, P. aeruginosa was not detected in most of the samples (73.7%). Numbers of S. maltophilia decreased with increasing time after treatment.

  13. Acoustic comfort in eating establishments

    DEFF Research Database (Denmark)

    Svensson, David; Jeong, Cheol-Ho; Brunskog, Jonas

    2014-01-01

    The subjective concept of acoustic comfort in eating establishments has been investigated in this study. The goal was to develop a predictive model for the acoustic comfort, by means of simple objective parameters, while also examining which other subjective acoustic parameters could help explain...... the feeling of acoustic comfort. Through several layers of anal ysis, acoustic comfort was found to be rather complex, and could not be explained entirely by common subjective parameters such as annoyance, intelligibility or privacy. A predictive model for the mean acoustic comfort for an eating establishment...

  14. Phononic crystals and acoustic metamaterials

    Directory of Open Access Journals (Sweden)

    Ming-Hui Lu

    2009-12-01

    Full Text Available Phononic crystals have been proposed about two decades ago and some important characteristics such as acoustic band structure and negative refraction have stimulated fundamental and practical studies in acoustic materials and devices since then. To carefully engineer a phononic crystal in an acoustic “atom” scale, acoustic metamaterials with their inherent deep subwavelength nature have triggered more exciting investigations on negative bulk modulus and/or negative mass density. Acoustic surface evanescent waves have also been recognized to play key roles to reach acoustic subwavelength imaging and enhanced transmission.

  15. Studies on acoustic modelling techniques for CANDU reactors

    International Nuclear Information System (INIS)

    This paper reviews the current technology being used to predict acoustic resonance in fluid-filled piping systems. The paper also reports on the analysis of a simple benchmark experiment that yielded some valuable insights and understanding into acoustic damping. A volumetric drag formula for the ABAQUS code is presented. Its application in experiments has yielded better results than previously obtained using a constant volumetric drag. (author). 24 refs., 1 tab., 12 figs

  16. THE ORIGINS OF THE CASHLESS SOCIETY: CASH DISPENSERS, DIRECT TO ACCOUNT PAYMENTS AND THE DEVELOPMENT OF ON-LINE REAL-TIME NETWORKS, C.1965-1985

    Directory of Open Access Journals (Sweden)

    Bernardo Bátiz-Lazo

    2014-07-01

    Full Text Available This article explores the technological choices made at the dawn of the massification of retail finance. We describe and analyze the early development of electronic banking and the foundations of the cashless society through the experiences of organizations with similar governance in two different competitive environments — Swedish and British savings banks. We document how the adoption of direct-to-account wage deposits and the subsequent deployment of networks of cash dispensers interacted with the adoption of on-line real-time (OLRT computing, and distinguish on- line and OLRT communication as distinct stages in the evolution of computer networks. We emphasize the role of middle managers in the selection of alternative technologies and show how delivering a cashless society proved more difficult than anticipated.

  17. Identification of risks associated with the prescribing and dispensing of oral anticancer medicines in Ireland.

    LENUS (Irish Health Repository)

    Hammond, Lisa

    2012-09-09

    Background Oral anticancer medicines (OAM) facilitate transfer of cancer care into the community, where safeguards developed in hospitals that control their prescribing, dispensing and administration may not exist. Objective To determine if the systems of prescribing and dispensing OAM in Ireland facilitate clinical verification of the prescription, thereby ensuring treatment is tailored and appropriate for the patient. Setting Randomly selected community pharmacies in Ireland and all Irish hospitals with cancer services. Method A questionnaire was sent to a random selection of Irish community pharmacists. A different questionnaire was sent to all Irish hospitals treating cancer patients. One hundred OAM prescriptions were retrospectively reviewed, to assess the information presented and the potential barriers to a community pharmacist performing a clinical verification of the prescription. Main outcome measure Community pharmacist survey: problems experienced when dispensing OAM and risk factors identified with the current system. Hospital pharmacist survey: proportion of hospitals that clinically verify prescriptions for parenteral versus oral anticancer medicines and associated policies. OAM prescription review: proportion of OAM prescriptions that contained sufficient information for a community pharmacist to clinically verify the prescription and safely dispense the medication. Results Sixty-four percent of community pharmacist respondents felt they did not have enough information available to them to safely dispense these prescriptions, and 74 % felt that patients are at risk with the current Irish system of prescribing and dispensing OAM. Irish hospitals do not have systems to ensure that all OAM prescriptions are clinically verified by a pharmacist. Seventeen different agents were prescribed on the prescriptions reviewed. The information provided to the community pharmacist would have allowed them to clinically verify 7 % of the OAM prescriptions

  18. Wavefront Modulation and Subwavelength Diffractive Acoustics with an Acoustic Metasurface

    OpenAIRE

    Xie, Yangbo; Wang, Wenqi; Chen, Huanyang; Konneker, Adam; Popa, Bogdan-Ioan; Cummer, Steven A.

    2014-01-01

    Metasurfaces are a family of novel wavefront shaping devices with planar profile and subwavelength thickness. Acoustic metasurfaces with ultralow profile yet extraordinary wave manipulating properties would be highly desirable for improving the performance of many acoustic wave-based applications. However, designing acoustic metasurfaces with similar functionality as their electromagnetic counterparts remains challenging with traditional metamaterial design approaches. Here we present a desig...

  19. ACOUSTICS IN ARCHITECTURAL DESIGN, AN ANNOTATED BIBLIOGRAPHY ON ARCHITECTURAL ACOUSTICS.

    Science.gov (United States)

    DOELLE, LESLIE L.

    THE PURPOSE OF THIS ANNOTATED BIBLIOGRAPHY ON ARCHITECTURAL ACOUSTICS WAS--(1) TO COMPILE A CLASSIFIED BIBLIOGRAPHY, INCLUDING MOST OF THOSE PUBLICATIONS ON ARCHITECTURAL ACOUSTICS, PUBLISHED IN ENGLISH, FRENCH, AND GERMAN WHICH CAN SUPPLY A USEFUL AND UP-TO-DATE SOURCE OF INFORMATION FOR THOSE ENCOUNTERING ANY ARCHITECTURAL-ACOUSTIC DESIGN…

  20. Practical acoustic emission testing

    CERN Document Server

    2016-01-01

    This book is intended for non-destructive testing (NDT) technicians who want to learn practical acoustic emission testing based on level 1 of ISO 9712 (Non-destructive testing – Qualification and certification of personnel) criteria. The essential aspects of ISO/DIS 18436-6 (Condition monitoring and diagnostics of machines – Requirements for training and certification of personnel, Part 6: Acoustic Emission) are explained, and readers can deepen their understanding with the help of practice exercises. This work presents the guiding principles of acoustic emission measurement, signal processing, algorithms for source location, measurement devices, applicability of testing methods, and measurement cases to support not only researchers in this field but also and especially NDT technicians.

  1. Passive broadband acoustic thermometry

    Science.gov (United States)

    Anosov, A. A.; Belyaev, R. V.; Klin'shov, V. V.; Mansfel'd, A. D.; Subochev, P. V.

    2016-04-01

    The 1D internal (core) temperature profiles for the model object (plasticine) and the human hand are reconstructed using the passive acoustothermometric broadband probing data. Thermal acoustic radiation is detected by a broadband (0.8-3.5 MHz) acoustic radiometer. The temperature distribution is reconstructed using a priori information corresponding to the experimental conditions. The temperature distribution for the heated model object is assumed to be monotonic. For the hand, we assume that the temperature distribution satisfies the heat-conduction equation taking into account the blood flow. The average error of reconstruction determined for plasticine from the results of independent temperature measurements is 0.6 K for a measuring time of 25 s. The reconstructed value of the core temperature of the hand (36°C) generally corresponds to physiological data. The obtained results make it possible to use passive broadband acoustic probing for measuring the core temperatures in medical procedures associated with heating of human organism tissues.

  2. Acoustic detection of pneumothorax

    Science.gov (United States)

    Mansy, Hansen A.; Royston, Thomas J.; Balk, Robert A.; Sandler, Richard H.

    2003-04-01

    This study aims at investigating the feasibility of using low-frequency (pneumothorax detection were tested in dogs. In the first approach, broadband acoustic signals were introduced into the trachea during end-expiration and transmitted waves were measured at the chest surface. Pneumothorax was found to consistently decrease pulmonary acoustic transmission in the 200-1200-Hz frequency band, while less change was observed at lower frequencies (ppneumothorax states (pPneumothorax was found to be associated with a preferential reduction of sound amplitude in the 200- to 700-Hz range, and a decrease of sound amplitude variation (in the 300 to 600-Hz band) during the respiration cycle (pPneumothorax changed the frequency and decay rate of percussive sounds. These results imply that certain medical conditions may be reliably detected using appropriate acoustic measurements and analysis. [Work supported by NIH/NHLBI #R44HL61108.

  3. A Century of Acoustic Metrology

    DEFF Research Database (Denmark)

    Rasmussen, Knud

    1998-01-01

    The development in acoustic measurement technique over the last century is reviewed with special emphasis on the metrological aspect.......The development in acoustic measurement technique over the last century is reviewed with special emphasis on the metrological aspect....

  4. Advanced Active Acoustics Lab (AAAL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Active Acoustics Lab (AAAL) is a state-of-the-art Undersea Warfare (USW) acoustic data analysis facility capable of both active and passive underwater...

  5. Research and practice of intelligent scrub dispensing system in operation room under process reengineering%基于流程再造的手术室智能更衣系统的研究与实践

    Institute of Scientific and Technical Information of China (English)

    凌蒙蒙; 张群瑜; 潘传迪

    2016-01-01

    目的:采用信息技术优化手术室更衣流程,改善手工流程的不足。方法:集成自助更衣机、CPU卡、电子储物柜、红外感应器等设备,开发手术室智能更衣软、硬件系统。结果:完成手术室智能更衣系统研发并投入正常运行,实现手术人员签到和签退、自动出衣、自动分配及回收储物柜、回收手术衣等功能。结论:手术室智能更衣系统对优化手术室更衣流程,缩短医务人员术前更衣时间,改善手术室环境,节约人力成本,提高服务效率具有积极的作用。%Objective: To optimize scrub dispensing process in operating room and replace previous manual process by information technology. Methods: Integrate self-service scrub dispensing machine, CPU card, electronic lockers, infrared sensors and other equipment were used to develop intelligent scrub dispensing hardware and software system in operation room. Results: The system is developed and put into normal operation. The intelligent scrub dispensing system achieves automatic operation personnel sign-in and sign-out, self serving surgical gowns, automatic allocation and locker reuse, self-recycle of dirty surgical gowns and other functions. Conclusions: The intelligent scrub dispensing system in operation room is a positive effect on optimizing the scrub dispensing process in operating room, shorting the time of medical personnel to change surgical gowns, improving the environment of the operation room, reducing labor costs, improving the service efficiency.

  6. 压电气体混合驱动式喷射点胶阀的设计与实验%Design and experiment for the piezoelectric-gas hybrid driven jet dispensing valve

    Institute of Scientific and Technical Information of China (English)

    焦晓阳; 刘建芳; 丁宁宁; 路崧

    2013-01-01

    Considering that the piezoelectric materials can be used for jet dispensing and can be widely applied in microelectronics packaging, a new type of piezoelectric/gas hybrid driven non-contact jet dispensing valve has been developed. This paper expounds upon the working principles of the valve, and uses FLUENT dynamic grid technol-ogy to analyze the relationship between the valve rod stroke and the glue solution to realize dispensing. Through the experiment, the factors which affect the dispensing quality of this valve were obtained. The 5 000 mPa·s high vis-cosity epoxy resin glue dispensing was realized with tungsten steel which has a nozzle diameter of 0.3 mm which was selected. The results show that the minimum diameter of the glue dot is 0.5 mm, dispensing frequency reaches 120 Hz, and the consistent error rate of the glue dot is under 5%.%为了实现压电喷射点胶,使压电喷射技术能广泛地应用到电子封装产业中,设计了一种压电/气体混合驱动式非接触喷射点胶阀.介绍了该点胶阀的工作原理,利用FLUENT动网格技术分析了阀杆行程与胶液实现喷射的关系,通过实验得到了影响点胶阀点胶质量的因素.实验选用直径为0.3 mm的钨钢喷嘴,实现了5000 mPa·s中高粘度环氧树脂胶结剂的喷射点胶,获得胶点最小直径为0.5 mm,点胶频率可达120 Hz,胶点一致性误差在5%以内.

  7. Acoustic GW detectors in the 2010 timeframe

    International Nuclear Information System (INIS)

    I consider the spectral sensitivities and bandwidths, in the standard quantum limit, of the narrowband spherical detectors, which would evolve from the present bar detectors and the wideband novel 'dual' detectors that have been proposed recently. If appropriate advanced fabrication and read-out technologies are developed, both kinds of GW acoustic detectors would play a relevant role in the near-kHz frequency region

  8. Densitometry By Acoustic Levitation

    Science.gov (United States)

    Trinh, Eugene H.

    1989-01-01

    "Static" and "dynamic" methods developed for measuring mass density of acoustically levitated solid particle or liquid drop. "Static" method, unknown density of sample found by comparison with another sample of known density. "Dynamic" method practiced with or without gravitational field. Advantages over conventional density-measuring techniques: sample does not have to make contact with container or other solid surface, size and shape of samples do not affect measurement significantly, sound field does not have to be know in detail, and sample can be smaller than microliter. Detailed knowledge of acoustic field not necessary.

  9. Acoustic classification of dwellings

    DEFF Research Database (Denmark)

    Berardi, Umberto; Rasmussen, Birgit

    2014-01-01

    insulation performance, national schemes for sound classification of dwellings have been developed in several European countries. These schemes define acoustic classes according to different levels of sound insulation. Due to the lack of coordination among countries, a significant diversity in terms...... of descriptors, number of classes, and class intervals occurred between national schemes. However, a proposal “acoustic classification scheme for dwellings” has been developed recently in the European COST Action TU0901 with 32 member countries. This proposal has been accepted as an ISO work item. This paper...

  10. Strong acoustic wave action

    Science.gov (United States)

    Gokhberg, M. B.

    1983-07-01

    Experiments devoted to acoustic action on the atmosphere-magnetosphere-ionosphere system using ground based strong explosions are reviewed. The propagation of acoustic waves was observed by ground observations over 2000 km in horizontal direction and to an altitude of 200 km. Magnetic variations up to 100 nT were detected by ARIEL-3 satellite near the epicenter of the explosion connected with the formation of strong field aligned currents in the magnetosphere. The enhancement of VLF emission at 800 km altitude is observed.

  11. Structural Acoustics and Vibrations

    Science.gov (United States)

    Chaigne, Antoine

    This structural chapter is devoted to vibrations of structures and to their coupling with the acoustic field. Depending on the context, the radiated sound can be judged as desirable, as is mostly the case for musical instruments, or undesirable, like noise generated by machinery. In architectural acoustics, one main goal is to limit the transmission of sound through walls. In the automobile industry, the engineers have to control the noise generated inside and outside the passenger compartment. This can be achieved by means of passive or active damping. In general, there is a strong need for quieter products and better sound quality generated by the structures in our daily environment.

  12. Moving Liquids with Sound: The Physics of Acoustic Droplet Ejection for Robust Laboratory Automation in Life Sciences.

    Science.gov (United States)

    Hadimioglu, Babur; Stearns, Richard; Ellson, Richard

    2016-02-01

    Liquid handling instruments for life science applications based on droplet formation with focused acoustic energy or acoustic droplet ejection (ADE) were introduced commercially more than a decade ago. While the idea of "moving liquids with sound" was known in the 20th century, the development of precise methods for acoustic dispensing to aliquot life science materials in the laboratory began in earnest in the 21st century with the adaptation of the controlled "drop on demand" acoustic transfer of droplets from high-density microplates for high-throughput screening (HTS) applications. Robust ADE implementations for life science applications achieve excellent accuracy and precision by using acoustics first to sense the liquid characteristics relevant for its transfer, and then to actuate transfer of the liquid with customized application of sound energy to the given well and well fluid in the microplate. This article provides an overview of the physics behind ADE and its central role in both acoustical and rheological aspects of robust implementation of ADE in the life science laboratory and its broad range of ejectable materials.

  13. Variable-Position Acoustic Levitation

    Science.gov (United States)

    Barmatz, M. B.; Stoneburner, J. D.; Jacobi, N.; Wang, T. G.

    1983-01-01

    Method of acoustic levitation supports objects at positions other than acoustic nodes. Acoustic force is varied so it balances gravitational (or other) force, thereby maintaining object at any position within equilibrium range. Levitation method applicable to containerless processing. Such objects as table-tennis balls, hollow plastic spheres, and balsa-wood spheres levitated in laboratory by new method.

  14. Development of suitable potting material for dispenser cathodes of a high power microwave tube

    Energy Technology Data Exchange (ETDEWEB)

    Pal, Kalyan S.; Ghosh, Sumana; Dandapat, Nandadulal [Bio-Ceramics and Coating Division, CSIR - Central Glass and Ceramic Research Institute, 196, Raja S.C. Mullick Road, Kolkata 700 032, West Bengal (India); Datta, Someswar, E-mail: sdatta@cgcri.res.in [Bio-Ceramics and Coating Division, CSIR - Central Glass and Ceramic Research Institute, 196, Raja S.C. Mullick Road, Kolkata 700 032, West Bengal (India); Basu, Debabrata [Bio-Ceramics and Coating Division, CSIR - Central Glass and Ceramic Research Institute, 196, Raja S.C. Mullick Road, Kolkata 700 032, West Bengal (India); Raju, R.S. [Microwave Tubes Division, CSIR - Central Electronics Engineering Research Institute, Pilani 333031, Rajasthan (India)

    2012-02-15

    Highlights: Black-Right-Pointing-Pointer Potting material. Black-Right-Pointing-Pointer Doped alumina. Black-Right-Pointing-Pointer Non-shrinkable. Black-Right-Pointing-Pointer Dispenser cathode. Black-Right-Pointing-Pointer Microwave tube. - Abstract: The present study aims to develop suitable advanced potting material for modern high performance dispenser cathodes for high power microwave tube through refinement of the alumina microstructure by using suitable dopant. Calcium oxide was selected as a dopant material and the resultant materials were characterized by X-ray diffraction studies and the microstructure monitored by SEM study and EDX analysis. The shrinkage, thermal and electrical properties of the resultant material was evaluated to establish its suitability to function as an advanced potting material.

  15. Picoliter Drop-On-Demand Dispensing for Multiplex Liquid Cell Transmission Electron Microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Patterson, Joseph P.; Parent, Lucas R.; Cantlon, Joshua; Eickhoff, Holger; Bared, Guido; Evans, James E.; Gianneschi, Nathan C.

    2016-06-03

    Liquid Cell Transmission Electron Microscopy (LCTEM) provides a unique insight into the dynamics of nanoparticles in solution. Controlling the mixing of multiple solutions within the liquid cells remains a key hurdle in our ability to study nanoparticle formation/modifications through conventional synthesis i.e. by mixing solutions. Here, we report that piezo dispensing techniques, allow for the mixing of multiple solutions directly within the viewing area. This technique deposits pL droplets of various aqueous and organic solutions onto the liquid cell window, prior to assembly of the cell in a fully controlled manner. This proof of concept shows the great potential for using picoliter dispensing in combination with LCTEM to observe nanoparticle synthesis or modification by solution phase mixing and the creation of chemical gradients.

  16. On-chip liquid storage and dispensing for lab-on-a-chip applications

    International Nuclear Information System (INIS)

    This work presents novel components for on-chip storage and dispensing inside a lab-on-a-chip (LOC) for applications in immunoassay point-of-care testing (POCT), where incubation and washing steps are essential. It involves easy-to-use on-chip solutions for the sequential thermo-hydraulic actuation of liquids. The novel concept of combining the use of a rubber plug, both as a non-return valve cap and as a liquid injection interface of a sealed reservoir, allows simple filling of a sterilized cavity, as well as the storage and dispensing of reagent and washing buffer liquids. Segmenting the flow with air spacers enables effective rinsing and the use of small volumes of on-chip stored liquids. The chip uses low-resistance resistors as heaters in the paraffin actuator, providing the low-voltage actuation that is preferred for handheld battery driven instruments

  17. The way to reduce electrical charge of a droplet dispensed from a pipette tip

    CERN Document Server

    Choi, Dongwhi; Im, Do Jin; Kim, Dong Sung

    2013-01-01

    Recently, our group reported that an any aqueous droplet dispensed from a pipette tip has considerable amount of electrical charge. This natural electrical charge of a droplet could cause undesired, unfamiliar experimental results. Since the origin of the charge of a droplet is related to the pipette tip material, we modified the inside material of the pipette tip with poly(dimethylsiloxane)-graphene nanocomposites. The droplets dispensed from the modified pipette tip has lower electrical charge than that from the common pipette tip. We compare the experimental results with the droplets from common pipette tip and modified pipette tip. This fluid dynamics video includes the principle of the spontaneous electrification of the droplet and the results of the droplet in oil experiments.

  18. ACOUSTIC RADIATION ENERGY AT A VARIATION OF THE COMPOSITE MECHANICAL DESTRUCTION AREA

    Directory of Open Access Journals (Sweden)

    Sergii Filonenko

    2016-06-01

    Full Text Available Purpose: The technological parameters of composite materials machining and also cutting tool state determine deforming and destruction of their surface layers conditions. Change of this conditions results to appearance of miscellaneous defects, loss of quality and produced items reliability. Therefore, optimization, control, diagnosis and monitoring of composite materials machining technological parameters are directed on obtaining the items given quality. For the solution of these problems tasks carry out researches of technological processes with usage of different methods. One of such methods is the acoustic emission method. Methods: The simulation and analysis of acoustic radiation energy parameters is carried out at change of composite material machining depth for prevailing mechanical destruction its surface layer. Results: We showed that to composite material machining the acoustic radiation energy has continuous nature. The ascending of composite material machining depth results to increase of acoustic emission statistical energy parameters. The regularity of acoustic emission energy parameters change are obtained and described. Is showed, that acoustic radiation most sensing parameter is the acoustic emission signals energy average level dispersion. Discussion: The outcomes researches demonstrate regularity influencing of composite material machining depth on acoustic emission energy parameters. Thus the analysis of acoustic emission signals energy average level dispersion can be used at mining methods of diagnostic, monitoring and control of composite materials machining technological parameters.

  19. An Overview of Acoustic Telemetry

    Energy Technology Data Exchange (ETDEWEB)

    Drumheller, D.S.

    1992-03-24

    Acoustic telemetry has been a dream of the drilling industry for the past 50 years. It offers the promise of data rates which are one-hundred times greater than existing technology. Such a system would open the door to true logging-while-drilling technology and bring enormous profits to its developers. The oil and gas industry has led in most of the attempts to develop this type of telemetry system; however, very substantial efforts have also been made through government sponsored work in the geothermal industry. None of these previous attempts have lead to a commercial telemetry system. Conceptually, the problem looks easy. The basic idea is to produce an encoded sound wave at the bottom of the well, let it propagate up the steel drillpipe, and extract the data from the signal at the surface. Unfortunately, substantial difficulties arise. The first difficult problem is to produce the sound wave. Since the most promising transmission wavelengths are about 20 feet, normal transducer efficiencies are quite low. Compounding this problem is the structural complexity of the bottomhole assembly and drillstring. For example, the acoustic impedance of the drillstring changes every 30 feet and produces an unusual scattering pattern in the acoustic transmission. This scattering pattern causes distortion of the signal and is often confused with signal attenuation. These problems are not intractable. Recent work has demonstrated that broad frequency bands exist which are capable of transmitting data at rates up to 100 bits per second. Our work has also identified the mechanism which is responsible for the observed anomalies in the patterns of signal attenuation. Furthermore in the past few years a body of experience has been developed in designing more efficient transducers for application to metal Waveguides. The direction of future work is clear. New transducer designs which are more efficient and compatible with existing downhole power supplies need to be built and tested

  20. Modelling and Forecasting Branded and Generic Pharmaceutical Life Cycles: Assessment of the Number of Dispensed Units

    OpenAIRE

    S. Buxton; Kostas Nikolopoulos; Khammash, M.; Stern, P.

    2015-01-01

    In this paper, modelling and forecasting pharmaceutical life cycles are investigated, specifically at the time of patent expiry when the generic form of the product could be introduced to the market, while the branded form is still available for prescription. Assessing the number of dispensed units of branded and generic forms of pharmaceuticals is increasingly important due to the irrelatively large market value in the United Kingdom and the limited number of new ÔblockbusterÕ branded drugs....

  1. Elderly drug utilization in the community assessed through pharmacy dispensing data

    OpenAIRE

    Martínez Sánchez, Alina de las Mercedes

    2013-01-01

    People of 65 years and above now comprise a greater share of the world's population than ever before, and this proportion will increase during the 21st century. In Spain, between 55 and 90% of the elderly consume a drug. This study characterizes the use of drugs by elderly through dispensing data at the community pharmacy. This study was conducted at a community pharmacy in Madrid, Spain in 2011. A retrospective and descriptive consumption study was conducted using computerized ph...

  2. Influence of the Separation of Prescription and Dispensation of Medicine on Its Cost in Japanese Prefectures

    OpenAIRE

    Yokoi, Masayuki; Tashiro, Takao

    2014-01-01

    We studied how the separation of dispensing and prescribing of medicines between pharmacies and clinics (the “separation system”) can reduce internal medicine costs. To do so, we obtained publicly available data by searching electronic databases and official web pages of the Japanese government and non-profit public service corporations on the Internet. For Japanese medical institutions, participation in the separation system is optional. Consequently, the expansion rate of the separation sys...

  3. Prescription, Dispensation, and Generic Medicine Replacement Ratios: Influence on Japanese Medicine Costs

    OpenAIRE

    Yokoi, Masayuki; Tashiro, Takao

    2015-01-01

    This study used publicly available data to examine the effect of the separation of dispensing and prescribing medicines between pharmacists in pharmacies and doctors in medical institutions (the separation system) and the generic medicine replacement ratio on the cost of various medicines in Japanese prefectures. For Japanese medical institutions, participation in the separation system is optional. Consequently, the expansion rate of the separation system for each administrative district is h...

  4. Understanding of pictograms from the United States Pharmacopeia Dispensing Information (USP-DI) among elderly Brazilians

    OpenAIRE

    Barros IMC; Alcântara TS; Mesquita AR; Bispo ML; Rocha CE; Moreira VP; Lyra Junior DP

    2014-01-01

    Izadora MC Barros, Thaciana S Alcântara, Alessandra R Mesquita, Monica L Bispo, Chiara E Rocha, Vagner Porto Moreira, Divaldo P Lyra Junior Laboratory of Teaching and Research in Social Pharmacy (LEPFS), Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Brazil Objective: To assess the understanding and cultural acceptability of the United States Pharmacopeia Dispensing Information (USP-DI) in a group of elderly ...

  5. Evaluation of Pharmacists' Services for Dispensing Emergency Contraceptive Pills in Delhi, India: A Mystery Shopper Study

    OpenAIRE

    Saxena, Pikee; Mishra, Archana; Nigam, Aruna

    2016-01-01

    Background: Although emergency contraceptive pills are available over the counter, the quality of consultation, including key areas of contraceptive counseling and prevention of sexually transmitted infections (STI), has not been well documented. Objective: To evaluate actual pharmacist services while dispensing emergency contraception through a mystery shopper technique. Material and Methods: This cross-sectional study was conducted in 81 pharmacies situated in Delhi by 4 trained mystery sho...

  6. Evaluation of pharmacists' services for dispensing emergency contraceptive pills in Delhi, India: A mystery shopper study

    OpenAIRE

    Pikee Saxena; Archana Mishra; Aruna Nigam

    2016-01-01

    Background: Although emergency contraceptive pills are available over the counter, the quality of consultation, including key areas of contraceptive counseling and prevention of sexually transmitted infections (STI), has not been well documented. Objective: To evaluate actual pharmacist services while dispensing emergency contraception through a mystery shopper technique. Material and Methods: This cross-sectional study was conducted in 81 pharmacies situated in Delhi by 4 trained mystery sho...

  7. Automated dose dispensing service for primary healthcare patients: a systematic review

    OpenAIRE

    SinnemÀki, Juha; Sihvo, Sinikka; IsojÀrvi, Jaana; Blom, Marja; Airaksinen, Marja; MÀntylÀ, Antti

    2013-01-01

    Background An automated dose dispensing (ADD) service has been implemented in primary healthcare in some European countries. In this service, regularly used medicines are machine-packed into unit-dose bags for each time of administration. The aim of this study is to review the evidence for ADD’s influence on the appropriateness of medication use, medication safety, and costs in primary healthcare. Methods A literature search was performed in April 2012 in the most relevant databases (n = 10),...

  8. Oxygen transport in the internal xenon plasma of a dispenser hollow cathode

    OpenAIRE

    Capece, Angela M.; Polk, James E.; Mikellides, Ioannis G.; Shepherd, Joseph E.

    2014-01-01

    Reactive gases such as oxygen and water vapor modify the surface morphology of BaO dispenser cathodes and degrade the electron emission properties. For vacuum cathodes operating at fixed temperature, the emission current drops rapidly when oxygen adsorbs on top of the low work function surface. Previous experiments have shown that plasma cathodes are more resistant to oxygen poisoning and can operate with O_2 partial pressures one to two orders of magnitude higher than vacuum cathodes before ...

  9. Adverse selection? A multi-dimensional profile of people dispensed opioid analgesics for persistent non-cancer pain.

    Directory of Open Access Journals (Sweden)

    Kris D Rogers

    Full Text Available OBJECTIVES: This study investigates utilisation patterns for prescription opioid analgesics in the Australian community and how these are associated with a framework of individual-level factors related to healthcare use. METHODS: Self-reported demographic and health information from participants in the 45 and Up Study cohort were linked to pharmaceutical claims from 2006-2009. Participants comprised 19,816 people with ≥1 opioid analgesic dispensing in the 12-months after recruitment to the cohort and 79,882 people not dispensed opioid analgesics. All participants were aged ≥45 years, were social security pharmaceutical beneficiaries, with no history of cancer. People dispensed opioid analgesics were classified as having acute (dispensing period <90 days, episodic (≥90 days and <3 'authority' prescriptions for increased quantity supply or long-term treatment (≥90 days and ≥3 authority prescriptions. RESULTS: Of participants dispensed opioid analgesic 52% received acute treatment, 25% episodic treatment and 23% long-term treatment. People dispensed opioid analgesics long-term had an average of 14.9 opioid analgesic prescriptions/year from 2.0 doctors compared with 1.5 prescriptions from 1.1 doctors for people receiving acute treatment. People dispensed opioid analgesics reported more need-related factors such as poorer physical functioning and higher psychological distress. Long-term users were more likely to have access-related factors such as low-income and living outside major cities. After simultaneous adjustment, association with predisposing health factors and access diminished, but indicators of need such as osteoarthritis treatment, paracetamol use, and poor physical function were the strongest predictors for all opioid analgesic users. CONCLUSIONS: People dispensed opioid analgesics were in poorer health, reported higher levels of distress and poorer functioning than people not receiving opioid analgesics. Varying dispensing

  10. From Architectural Acoustics to Acoustical Architecture Using Computer Simulation

    DEFF Research Database (Denmark)

    Schmidt, Anne Marie Due; Kirkegaard, Poul Henning

    2005-01-01

    Architectural acoustics design has in the past been based on simple design rules. However, with a growing complexity in architectural acoustics and the emergence of room acoustic simulation programmes with considerable potential, it is now possible to subjectively analyse and evaluate acoustic...... properties prior to the actual construction of a building. With the right tools applied, acoustic design can become an integral part of the architectural design process. The aim of this paper is to investigate the field of application that an acoustic simulation programme can have during an architectural...... acoustic design process and to set up a strategy to develop future programmes. The emphasis is put on the first three out of four phases in the working process of the architect and a case study is carried out in which each phase is represented by typical results ? as exemplified with reference...

  11. “Adverse Drug Reaction Reporting” Knowledge, Attitude and Practices of Community Pharmacy Dispensers in Dar es salaam, Tanzania

    OpenAIRE

    Shimwela, Grace Mng’ong’o

    2011-01-01

    Under reporting of adverse drug reactions (ADRs) by healthcare personnel is a common problem of many Pharmacovigilence programs. Lack of involvement of healthcare professionals such as pharmacists and other pharmaceutical dispensers has been cited as one of the reasons for under reporting. Pharmaceutical dispensers in the community pharmacies are in unique position by virtue of their training and profession to observe ADRs in patients, as many patients often try to avoid doctor consultation f...

  12. Use of direct washing of chemical dispense nozzle for defect control

    Science.gov (United States)

    Linnane, Michael; Mack, George; Longstaff, Christopher; Winter, Thomas

    2006-03-01

    Demands for continued defect reduction in 300mm IC manufacturing are driving process engineers to examine all aspects of the chemical apply process for improvement. Historically, the defect contribution from photoresist apply nozzles has been minimized through a carefully controlled process of "dummy dispenses" to keep the photoresist in the tip "fresh" and remove any solidified material, a preventive maintenance regime involving periodic cleaning or replacing of the nozzles, and reliance on a pool of solvent within the nozzle storage block to keep the photoresist from solidifying at the nozzle tip. The industry standard has worked well for the most part but has limitations in terms of cost effectiveness and absolute defect elimination. In this study, we investigate the direct washing of the chemical apply nozzle to reduce defects seen on the coated wafer. Data is presented on how the direct washing of the chemical dispense nozzle can be used to reduce coating related defects, reduce material costs from the reduction of "dummy dispense", and can reduce equipment downtime related to nozzle cleaning or replacement.

  13. Raw Milk Hygiene at Local Markets and Automatic Milk Dispenser Machines

    Directory of Open Access Journals (Sweden)

    Gheorghe Şteţca

    2014-11-01

    Full Text Available In Romania, direct sales of raw milk to the final consumer is developed based on the local regulations. These are in accordance to European Regulation that must meet some quality requirements for the total number of germs, somatic cells, without antibiotics, coming from healthy animals who did not suffer from diseases that can be transmitted to humans through milk. Raw milk is sold in Romania in local markets and by automatic milk dispenser machines. Based on these regulations, a study regarding the quality and security to human health of raw milk was conducted on the commercialized milk in local markets and automatic milk dispensers. During May-June 2014 samples of raw milk were collected from Cluj-Napoca local markets and automatic milk dispensers. All samples were kept to refrigeration conditions until the moment of analyze which took place at the sampling day. The following parameters were taken into account: fat content, protein, casein, lactose, nonfat dry matter, pH, milk freezing point, added water, antibiotics residues, milk urea, number of germ cells and somatic cells. All obtained results were verified by the validated methods applied. Our research can be forward conducted in order to verify the hygiene and composition of milk from the whole dairy chain. 

  14. Underwater Acoustic Networking Techniques

    CERN Document Server

    Otnes, Roald; Casari, Paolo; Goetz, Michael; Husøy, Thor; Nissen, Ivor; Rimstad, Knut; van Walree, Paul; Zorzi, Michele

    2012-01-01

    This literature study presents an overview of underwater acoustic networking. It provides a background and describes the state of the art of all networking facets that are relevant for underwater applications. This report serves both as an introduction to the subject and as a summary of existing protocols, providing support and inspiration for the development of network architectures.

  15. Evoked acoustic emission

    DEFF Research Database (Denmark)

    Elberling, C; Parbo, J; Johnsen, N J;

    1985-01-01

    Stimulated acoustic emissions were recorded in response to tonal stimuli at 60 dB p.e. SPL in a small group of normal-hearing adults. Power spectral analysis reveals that the evoked activity from each ear contains energy in preferential frequency bands and the change of stimulus frequency has only...

  16. Surface Acoustic Wave Devices

    DEFF Research Database (Denmark)

    Dühring, Maria Bayard

    The work of this project is concerned with the simulation of surface acoustic waves (SAW) and topology optimization of SAW devices. SAWs are elastic vibrations that propagate along a material surface and are extensively used in electromechanical filters and resonators in telecommunication. A new...

  17. Portable acoustic myography

    DEFF Research Database (Denmark)

    Harrison, Adrian Paul; Danneskiold-Samsøe, Bente; Bartels, Else Marie

    2013-01-01

    Muscle sound gives a local picture of muscles involved in a particular movement and is independent of electrical signals between nerve and muscle. Sound recording (acoustic myography) is a well-known noninvasive technique that has suffered from not being easily applicable, as well as not being ab...

  18. Compliance towards dispensed medication labelling standards: a cross-sectional study in the state of Penang, Malaysia.

    Science.gov (United States)

    Neoh, Chin Fen; Hassali, Mohamed Azmi; Shafie, Asrul Akmal; Awaisu, Ahmed; Tambyappa, Jayabalan

    2009-09-01

    Good medicine labelling practice is vital to ensure safe use of medicines. Non-compliance to labelling standards is a potential source of medication errors. This study was intended to evaluate and compare compliance towards labelling standard for dispensed medications between community pharmacists and general practitioners in Penang, Malaysia. A total of 128 community pharmacies and 26 general practitioners' clinics were visited. Using 'Simulated Client Method' (SCM), data were collected on the medications dispensed upon presentation of hypothetical common cold symptoms. The medications dispensed were evaluated for labelling adequacy. Result revealed that majority of the dispensed medications obtained were not labelled according to regulatory requirements. However, general practitioners complied better than community pharmacists in terms of labelling for: name of patient (p<0.001), details of supplier (p<0.001), dosage of medication (p=0.023), frequency to take medication (p=0.023), patient's reference number (p<0.001), date of supply (p<0.001), special instructions for medication (p=0.008), storage requirements (p=0.002), and indication for medication (p<0.001). Conversely, community pharmacists labelled dispensed medications with the words "Controlled Medicine" more often than did general practitioners (p<0.001). Although laws for labelling dispensed medicines are in place, most community pharmacists and general practitioners did not comply accordingly, thereby putting patients' safety at risks of medication errors.

  19. Pediatric burns due to hot water from water dispenser: a neglected issue that should be highly concerned

    Institute of Scientific and Technical Information of China (English)

    MA Bing; XI Hui-jun; WANG Jia-lin; YAN Ying; TANG Hong-tai; ZHU Shi-hui; L(U) Kai-yang; XIA Zhao-fan

    2012-01-01

    Background More and more Chinese drink hot water from water dispensers while many children were scalded due to this change.The present study aimed to propose a feasible strategy for prevention.Methods A retrospective study was conducted for all water dispensers related pediatric burns admitted to Changhai Hospital from January 2005 to December 2009.Results The number of new cases and incidences of pediatric burns due to hot water from water dispensers was significantly increasing year after year.In the total 238 involved cases,175 cases happened on males and 78.9% were at the age of 1-4 years.The burn areas were mainly located in upper extremities.All water dispensers in the surveyed families had no isolate protection devices and 85.2% of their locations were easy for children to reach.Nearly half of the children were in the same room with their guardians when injured.Total 196 burned children were playing the taps of water dispensers before injured,unfortunately,80.6% of them have not been stopped until burned.Conclusion As the kind of bums is quite serious and with bad outcome,some recommendations should be followed,such as buying water dispensers with protection devices,keeping children from touching them and so on.

  20. Holograms for acoustics

    Science.gov (United States)

    Melde, Kai; Mark, Andrew G.; Qiu, Tian; Fischer, Peer

    2016-09-01

    Holographic techniques are fundamental to applications such as volumetric displays, high-density data storage and optical tweezers that require spatial control of intricate optical or acoustic fields within a three-dimensional volume. The basis of holography is spatial storage of the phase and/or amplitude profile of the desired wavefront in a manner that allows that wavefront to be reconstructed by interference when the hologram is illuminated with a suitable coherent source. Modern computer-generated holography skips the process of recording a hologram from a physical scene, and instead calculates the required phase profile before rendering it for reconstruction. In ultrasound applications, the phase profile is typically generated by discrete and independently driven ultrasound sources; however, these can only be used in small numbers, which limits the complexity or degrees of freedom that can be attained in the wavefront. Here we introduce monolithic acoustic holograms, which can reconstruct diffraction-limited acoustic pressure fields and thus arbitrary ultrasound beams. We use rapid fabrication to craft the holograms and achieve reconstruction degrees of freedom two orders of magnitude higher than commercial phased array sources. The technique is inexpensive, appropriate for both transmission and reflection elements, and scales well to higher information content, larger aperture size and higher power. The complex three-dimensional pressure and phase distributions produced by these acoustic holograms allow us to demonstrate new approaches to controlled ultrasonic manipulation of solids in water, and of liquids and solids in air. We expect that acoustic holograms will enable new capabilities in beam-steering and the contactless transfer of power, improve medical imaging, and drive new applications of ultrasound.

  1. The acoustic communities: Definition, description and ecological role.

    Science.gov (United States)

    Farina, Almo; James, Philip

    2016-09-01

    An acoustic community is defined as an aggregation of species that produces sound by using internal or extra-body sound-producing tools. Such communities occur in aquatic (freshwater and marine) and terrestrial environments. An acoustic community is the biophonic component of a soundtope and is characterized by its acoustic signature, which results from the distribution of sonic information associated with signal amplitude and frequency. Distinct acoustic communities can be described according to habitat, the frequency range of the acoustic signals, and the time of day or the season. Near and far fields can be identified empirically, thus the acoustic community can be used as a proxy for biodiversity richness. The importance of ecoacoustic research is rapidly growing due to the increasing awareness of the intrusion of anthropogenic sounds (technophonies) into natural and human-modified ecosystems and the urgent need to adopt more efficient predictive tools to compensate for the effects of climate change. The concept of an acoustic community provides an operational scale for a non-intrusive biodiversity survey and analysis that can be carried out using new passive audio recording technology, coupled with methods of vast data processing and storage. PMID:27262416

  2. Controlling sound with acoustic metamaterials

    DEFF Research Database (Denmark)

    Cummer, Steven A. ; Christensen, Johan; Alù, Andrea

    2016-01-01

    Acoustic metamaterials can manipulate and control sound waves in ways that are not possible in conventional materials. Metamaterials with zero, or even negative, refractive index for sound offer new possibilities for acoustic imaging and for the control of sound at subwavelength scales....... The combination of transformation acoustics theory and highly anisotropic acoustic metamaterials enables precise control over the deformation of sound fields, which can be used, for example, to hide or cloak objects from incident acoustic energy. Active acoustic metamaterials use external control to create......-scale metamaterial structures and converting laboratory experiments into useful devices. In this Review, we outline the designs and properties of materials with unusual acoustic parameters (for example, negative refractive index), discuss examples of extreme manipulation of sound and, finally, provide an overview...

  3. Technology

    Directory of Open Access Journals (Sweden)

    Xu Jing

    2016-01-01

    Full Text Available The traditional answer card reading method using OMR (Optical Mark Reader, most commonly, OMR special card special use, less versatile, high cost, aiming at the existing problems proposed a method based on pattern recognition of the answer card identification method. Using the method based on Line Segment Detector to detect the tilt of the image, the existence of tilt image rotation correction, and eventually achieve positioning and detection of answers to the answer sheet .Pattern recognition technology for automatic reading, high accuracy, detect faster

  4. Increasing Access to Subsidized Artemisinin-based Combination Therapy through Accredited Drug Dispensing Outlets in Tanzania

    Directory of Open Access Journals (Sweden)

    Gabra Michael

    2011-06-01

    Full Text Available Abstract Background In Tanzania, many people seek malaria treatment from retail drug sellers. The National Malaria Control Program identified the accredited drug dispensing outlet (ADDO program as a private sector mechanism to supplement the distribution of subsidized artemisinin-based combination therapies (ACTs from public facilities and increase access to the first-line antimalarial in rural and underserved areas. The ADDO program strengthens private sector pharmaceutical services by improving regulatory and supervisory support, dispenser training, and record keeping practices. Methods The government's pilot program made subsidized ACTs available through ADDOs in 10 districts in the Morogoro and Ruvuma regions, covering about 2.9 million people. The program established a supply of subsidized ACTs, created a price system with a cost recovery plan, developed a plan to distribute the subsidized products to the ADDOs, trained dispensers, and strengthened the adverse drug reactions reporting system. As part of the evaluation, 448 ADDO dispensers brought their records to central locations for analysis, representing nearly 70% of ADDOs operating in the two regions. ADDO drug register data were available from July 2007-June 2008 for Morogoro and from July 2007-September 2008 for Ruvuma. This intervention was implemented from 2007-2008. Results During the pilot, over 300,000 people received treatment for malaria at the 448 ADDOs. The percentage of ADDOs that dispensed at least one course of ACT rose from 26.2% during July-September 2007 to 72.6% during April-June 2008. The number of malaria patients treated with ACTs gradually increased after the start of the pilot, while the use of non-ACT antimalarials declined; ACTs went from 3% of all antimalarials sold in July 2007 to 26% in June 2008. District-specific data showed substantial variation among the districts in ACT uptake through ADDOs, ranging from ACTs representing 10% of all antimalarial sales

  5. Inquiry and practice of acoustic technology of the theater at home and abroad%近现代中外剧场声学技术探索与实践

    Institute of Scientific and Technical Information of China (English)

    黄帅; 刘燕彬

    2014-01-01

    以建筑声学的探索轨迹为线索,详细列举了近现代国内外著名剧场建设实际案例,介绍了建筑声学的发展状况,指出邀请专业的声学团队参与剧场的建筑设计是剧场建筑的发展趋势。%Taking the architectural acoustics inquiry as the routine,the paper lists famous theater construction practice at home and abroad,intro-duces architectural acoustic development conditions,and points out that inviting professional acoustic team to participating theater building design is the development trend of theater building.

  6. Investigation of bulk acoustic microwaves excited by an interdigital transducer

    Directory of Open Access Journals (Sweden)

    Reshotka O. G.

    2015-12-01

    Full Text Available Excitation of bulk and surface acoustic waves with the interdigital transducer (IDT, which is deposited on the surface of piezoelectric crystal, is widely used in the development of devices in acoustoelectronics and in the design of the microwave acousto-optic deflectors. Excitation of bulk acoustic waves by IDT in the devices on surface acoustic waves leads to the appearance of spurious signals. At the same time excitation of bulk acoustic waves with IDT from the surface of lithium niobate crystals allows creating high frequency acousto-optic deflectors, which makes possible to significantly simplify the technology of their production. Therefore, significant attention is paid to the task of excitation and distribution of bulk acoustic waves with IDT including recent times by the method of simulation of their excitation and distribution. The obtained theoretical results require experimental verification. This paper documents the visualization of acoustic beams excited with IDT from the XY-surface of lithium niobate crystals. The Bragg cells with LiNbO3 crystals coated with IDT with a different period of electrodes were manufactured for the experimental research of excitation and distribution of bulk acoustic waves. Visualization results have shown that the acoustic waves excited with IDT distribute in both the Fresnel zone and the Fraunhofer zone. The length of these zones is caused by individual elementary emitters of which consists the IDT (by their size. At the same time the far zone for IDT is located at distances much greater than the actual size of the LiNbO3 crystals. This peculiarity is not always taken into account when calculating diffraction. The achieved results can be used to design high-frequency acousto-optic devices, as well as in the development of devices based on surface acoustic waves.

  7. Flat acoustic lens by acoustic grating with curled slits

    KAUST Repository

    Peng, Pai

    2014-10-01

    We design a flat sub-wavelength lens that can focus acoustic wave. We analytically study the transmission through an acoustic grating with curled slits, which can serve as a material with tunable impedance and refractive index for acoustic waves. The effective parameters rely on the geometry of the slits and are independent of frequency. A flat acoustic focusing lens by such acoustic grating with gradient effective refractive index is designed. The focusing effect is clearly observed in simulations and well predicted by the theory. We demonstrate that despite the large impedance mismatch between the acoustic lens and the matrix, the intensity at the focal point is still high due to Fabry-Perot resonance.

  8. Acoustic energy harvesting based on a planar acoustic metamaterial

    Science.gov (United States)

    Qi, Shuibao; Oudich, Mourad; Li, Yong; Assouar, Badreddine

    2016-06-01

    We theoretically report on an innovative and practical acoustic energy harvester based on a defected acoustic metamaterial (AMM) with piezoelectric material. The idea is to create suitable resonant defects in an AMM to confine the strain energy originating from an acoustic incidence. This scavenged energy is converted into electrical energy by attaching a structured piezoelectric material into the defect area of the AMM. We show an acoustic energy harvester based on a meta-structure capable of producing electrical power from an acoustic pressure. Numerical simulations are provided to analyze and elucidate the principles and the performances of the proposed system. A maximum output voltage of 1.3 V and a power density of 0.54 μW/cm3 are obtained at a frequency of 2257.5 Hz. The proposed concept should have broad applications on energy harvesting as well as on low-frequency sound isolation, since this system acts as both acoustic insulator and energy harvester.

  9. 28th International Acoustical Imaging Symposium

    CERN Document Server

    André, Michael P; Andre, Michael; Arnold, Walter; Bamber, Jeff; Burov, Valentin; Chubachi, Noriyoshi; Erikson, Kenneth; Ermert, Helmut; Fink, Mathias; Gan, Woon S; Granz, Bernd; Greenleaf, James; Hu, Jiankai; Jones, Joie P; Khuri-Yakub, Pierre; Laugier, Pascal; Lee, Hua; Lees, Sidney; Levin, Vadim M; Maev, Roman; Masotti, Leonardo; Nowicki, Andrzej; O’Brien, William; Prasad, Manika; Rafter, Patrick; Rouseff, Daniel; Thijssen, Johan; Tittmann, Bernard; Tortoli, Piero; Steen, Anton; Waag, Robert; Wells, Peter; Acoustical Imaging

    2007-01-01

    The International Acoustical Imaging Symposium has been held continuously since 1968 as a unique forum for advanced research, promoting the sharing of technology, developments, methods and theory among all areas of acoustics. The interdisciplinary nature of the Symposium and the wide international participation are two of its main strengths. Scientists from around the world present their papers in an informal environment conducive to lively discussion and cross-fertilization. The fact that a loyal community of scientists has supported this Series since 1968 is evidence of its impact on the field. The Symposium Series continues to thrive in a busy calendar of scientific meetings without the infrastructure of a professional society. It does so because those who attend and those who rely on the Proceedings as a well-known reference work acknowledge its value. This Volume 28 of the Proceedings likewise contains an excellent collection of papers presented in six major categories, offering both a broad perspective ...

  10. An injectable acoustic transmitter for juvenile salmon

    Science.gov (United States)

    Deng, Z. D.; Carlson, T. J.; Li, H.; Xiao, J.; Myjak, M. J.; Lu, J.; Martinez, J. J.; Woodley, C. M.; Weiland, M. A.; Eppard, M. B.

    2015-01-01

    Salmon recovery and the potential detrimental effects of dams on fish have been attracting national attention due to the environmental and economic implications. In recent years acoustic telemetry has been the primary method for studying salmon passage. However, the size of the existing transmitters limits the minimum size of fish that can be studied, introducing a bias to the study results. We developed the first acoustic fish transmitter that can be implanted by injection instead of surgery. The new injectable transmitter lasts four times longer and weighs 30% less than other transmitters. Because the new transmitter costs significantly less to use and may substantially reduce adverse effects of implantation and tag burden, it will allow for study of migration behavior and survival of species and sizes of fish that have never been studied before. The new technology will lead to critical information needed for salmon recovery and the development of fish-friendly hydroelectric systems.

  11. Acoustic Tractor Beam

    Science.gov (United States)

    Démoré, Christine E. M.; Dahl, Patrick M.; Yang, Zhengyi; Glynne-Jones, Peter; Melzer, Andreas; Cochran, Sandy; MacDonald, Michael P.; Spalding, Gabriel C.

    2014-05-01

    Negative radiation forces act opposite to the direction of propagation, or net momentum, of a beam but have previously been challenging to definitively demonstrate. We report an experimental acoustic tractor beam generated by an ultrasonic array operating on macroscopic targets (>1 cm) to demonstrate the negative radiation forces and to map out regimes over which they dominate, which we compare to simulations. The result and the geometrically simple configuration show that the effect is due to nonconservative forces, produced by redirection of a momentum flux from the angled sides of a target and not by conservative forces from a potential energy gradient. Use of a simple acoustic setup provides an easily understood illustration of the negative radiation pressure concept for tractor beams and demonstrates continuous attraction towards the source, against a net momentum flux in the system.

  12. Acoustic absorption by sunspots

    Science.gov (United States)

    Braun, D. C.; Labonte, B. J.; Duvall, T. L., Jr.

    1987-01-01

    The paper presents the initial results of a series of observations designed to probe the nature of sunspots by detecting their influence on high-degree p-mode oscillations in the surrounding photosphere. The analysis decomposes the observed oscillations into radially propagating waves described by Hankel functions in a cylindrical coordinate system centered on the sunspot. From measurements of the differences in power between waves traveling outward and inward, it is demonstrated that sunspots appear to absorb as much as 50 percent of the incoming acoustic waves. It is found that for all three sunspots observed, the amount of absorption increases linearly with horizontal wavenumber. The effect is present in p-mode oscillations with wavelengths both significantly larger and smaller than the diameter of the sunspot umbrae. Actual absorption of acoustic energy of the magnitude observed may produce measurable decreases in the power and lifetimes of high-degree p-mode oscillations during periods of high solar activity.

  13. Acoustic absorption by sunspots

    Energy Technology Data Exchange (ETDEWEB)

    Braun, D.C.; Labonte, B.J.; Duvall, T.L. Jr.

    1987-08-01

    The paper presents the initial results of a series of observations designed to probe the nature of sunspots by detecting their influence on high-degree p-mode oscillations in the surrounding photosphere. The analysis decomposes the observed oscillations into radially propagating waves described by Hankel functions in a cylindrical coordinate system centered on the sunspot. From measurements of the differences in power between waves traveling outward and inward, it is demonstrated that sunspots appear to absorb as much as 50 percent of the incoming acoustic waves. It is found that for all three sunspots observed, the amount of absorption increases linearly with horizontal wavenumber. The effect is present in p-mode oscillations with wavelengths both significantly larger and smaller than the diameter of the sunspot umbrae. Actual absorption of acoustic energy of the magnitude observed may produce measurable decreases in the power and lifetimes of high-degree p-mode oscillations during periods of high solar activity. 10 references.

  14. Acoustic emission source modeling

    Directory of Open Access Journals (Sweden)

    Hora P.

    2010-07-01

    Full Text Available The paper deals with the acoustic emission (AE source modeling by means of FEM system COMSOL Multiphysics. The following types of sources are used: the spatially concentrated force and the double forces (dipole. The pulse excitation is studied in both cases. As a material is used steel. The computed displacements are compared with the exact analytical solution of point sources under consideration.

  15. The acoustics of snoring.

    Science.gov (United States)

    Pevernagie, Dirk; Aarts, Ronald M; De Meyer, Micheline

    2010-04-01

    Snoring is a prevalent disorder affecting 20-40% of the general population. The mechanism of snoring is vibration of anatomical structures in the pharyngeal airway. Flutter of the soft palate accounts for the harsh aspect of the snoring sound. Natural or drug-induced sleep is required for its appearance. Snoring is subject to many influences such as body position, sleep stage, route of breathing and the presence or absence of sleep-disordered breathing. Its presentation may be variable within or between nights. While snoring is generally perceived as a social nuisance, rating of its noisiness is subjective and, therefore, inconsistent. Objective assessment of snoring is important to evaluate the effect of treatment interventions. Moreover, snoring carries information relating to the site and degree of obstruction of the upper airway. If evidence for monolevel snoring at the site of the soft palate is provided, the patient may benefit from palatal surgery. These considerations have inspired researchers to scrutinize the acoustic characteristics of snoring events. Similarly to speech, snoring is produced in the vocal tract. Because of this analogy, existing techniques for speech analysis have been applied to evaluate snoring sounds. It appears that the pitch of the snoring sound is in the low-frequency range (noise-like', and has scattered energy content in the higher spectral sub-bands (>500 Hz). To evaluate acoustic properties of snoring, sleep nasendoscopy is often performed. Recent evidence suggests that the acoustic quality of snoring is markedly different in drug-induced sleep as compared with natural sleep. Most often, palatal surgery alters sound characteristics of snoring, but is no cure for this disorder. It is uncertain whether the perceived improvement after palatal surgery, as judged by the bed partner, is due to an altered sound spectrum. Whether some acoustic aspects of snoring, such as changes in pitch, have predictive value for the presence of

  16. Investigation of acoustic sensors to detect coconut rhinoceros beetle in Guam

    Science.gov (United States)

    The coconut rhinoceros beetle, Oryctes rhinoceros, was accidentally introduced into Guam last year and now threatens the Island’s forests and tourist industry. These large insects can be detected easily with acoustic sensors, and procedures are being developed to incorporate acoustic technology int...

  17. Teaching Acoustic Properties of Materials in Secondary School: Testing Sound Insulators

    Science.gov (United States)

    Hernandez, M. I.; Couso, D.; Pinto, R.

    2011-01-01

    Teaching the acoustic properties of materials is a good way to teach physics concepts, extending them into the technological arena related to materials science. This article describes an innovative approach for teaching sound and acoustics in combination with sound insulating materials in secondary school (15-16-year-old students). Concerning the…

  18. Acoustic and electo-acoustic design of the Country Music Hall of Fame and Museum in Nashville

    Science.gov (United States)

    Haas, Steve

    2003-04-01

    The Country Music Hall of Fame and Museum in Nashville is the newest major music museum to open in the United States. It represents the latest in acoustic and audio delivery technology to provide excellent sound quality and sound control for museum public, performance and exhibit spaces. The author will present some of the unique approaches and technologies that were first implemented into this facility and explain how the acoustic/electroacoustic interface allowed the Hall of Fame to maximize their use of sound in the exhibits as well as hold simultaneous special functions in many of the public spaces.

  19. Fundamentals of Shallow Water Acoustics

    CERN Document Server

    Katsnelson, Boris; Lynch, James

    2012-01-01

    Shallow water acoustics (SWA), the study of how low and medium frequency sound propagates and scatters on the continental shelves of the world's oceans, has both technical interest and a large number of practical applications. Technically, shallow water poses an interesting medium for the study of acoustic scattering, inverse theory, and propagation physics in a complicated oceanic waveguide. Practically, shallow water acoustics has interest for geophysical exploration, marine mammal studies, and naval applications. Additionally, one notes the very interdisciplinary nature of shallow water acoustics, including acoustical physics, physical oceanography, marine geology, and marine biology. In this specialized volume, the authors, all of whom have extensive at-sea experience in U.S. and Russian research efforts, have tried to summarize the main experimental, theoretical, and computational results in shallow water acoustics, with an emphasis on providing physical insight into the topics presented.

  20. Latest Trends in Acoustic Sensing

    Directory of Open Access Journals (Sweden)

    Cinzia Caliendo

    2014-03-01

    Full Text Available Acoustics-based methods offer a powerful tool for sensing applications. Acoustic sensors can be applied in many fields ranging from materials characterization, structural health monitoring, acoustic imaging, defect characterization, etc., to name just a few. A proper selection of the acoustic wave frequency over a wide spectrum that extends from infrasound (<20 Hz up to ultrasound (in the GHz–band, together with a number of different propagating modes, including bulk longitudinal and shear waves, surface waves, plate modes, etc., allow acoustic tools to be successfully applied to the characterization of gaseous, solid and liquid environments. The purpose of this special issue is to provide an overview of the research trends in acoustic wave sensing through some cases that are representative of specific applications in different sensing fields.

  1. High-Frequency Seafloor Acoustics

    CERN Document Server

    Jackson, Darrell R

    2007-01-01

    High-Frequency Seafloor Acoustics is the first book in a new series sponsored by the Office of Naval Research on the latest research in underwater acoustics. This exciting new title provides ready access to experimental data, theory, and models relevant to high-frequency seafloor acoustics and will be of interest to sonar engineers and researchers working in underwater acoustics. The physical characteristics of the seafloor affecting acoustic propagation and scattering are covered, including physical and geoacoustic properties and surface roughness. Current theories for acoustic propagation in sediments are presented along with corresponding models for reflection, scattering, and seafloor penetration. The main text is backed up by an extensive bibliography and technical appendices.

  2. Acoustical coupling of lizard eardrums

    DEFF Research Database (Denmark)

    Christensen-Dalsgaard, Jakob; Manley, Geoffrey A

    2008-01-01

    Lizard ears are clear examples of two-input pressure-difference receivers, with up to 40-dB differences in eardrum vibration amplitude in response to ipsi- and contralateral stimulus directions. The directionality is created by acoustical coupling of the eardrums and interaction of the direct...... is caused by the acoustic interaction of the two eardrums. The results can be largely explained by a simple acoustical model based on an electrical analog circuit....

  3. Room acoustic auralization with Ambisonics

    OpenAIRE

    Polack, Jean-Dominique; Leão Figueiredo, Fábio

    2012-01-01

    International audience During the year of 2009, the room acoustics group of the LAM (Équipe Lutheries, Acoustique, Musique de l’Institut Jean Le Rond d’Alembert - Université Pierre et Marie Curie, Paris) performed a series of acoustical measurements in music halls in Paris. The halls were chosen in regarding their importance to the historic, architectural or acoustic domains. The measured ensemble of fourteen rooms includes quite different architectural designs. The measurements were carri...

  4. Steam sterilization and automatic dispensing of [{sup 18}F]fludeoxyglucose (FDG) for injection

    Energy Technology Data Exchange (ETDEWEB)

    Karwath, Pascal [Department of Nuclear Medicine, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn (Germany) and MC-Pharma GmbH (MCP), Bonn (Germany)]. E-mail: p.karwath@uni-bonn.de; Sartor, Johannes [MC-Pharma GmbH (MCP), Bonn (Germany); Gries, Wolfgang [MC-Pharma GmbH (MCP), Bonn (Germany); Wodarski, Christine [MC-Pharma GmbH (MCP), Bonn (Germany); Dittmar, Claus [MC-Pharma GmbH (MCP), Bonn (Germany); Biersack, Hans J. [Department of Nuclear Medicine, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn (Germany); Guhlke, Stefan [Department of Nuclear Medicine, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn (Germany) and MC-Pharma GmbH (MCP), Bonn (Germany)]. E-mail: stefan.guhlke@ukb.uni-bonn.de

    2005-04-01

    For the purpose of implementing steam sterilization of 2-[{sup 18}F]FDG (FDG) in the final container into routine production, we have validated and established a fully automated dispensing and sterilization system, thereby considerably reducing the radiation burden to the personnel. Methods: The commercially available system combines aseptic dispensing of the product solution under a miniaturized laminar flow unit with subsequent steam sterilization, realized by heating of the product in the final containers by an autoclave included in the dispensing unit, thus incorporating current pharmaceutical manufacturing standards for the production of parental radiopharmaceuticals. The efficiency of the used sterilization cycle, the stability of FDG under the conditions of sterilization and the stability of the final product towards radiolysis was investigated with respect to various pH-formulations. Results: The system was found to be fully valid for filling of vials in a laminar flow class A (US-class 100) environment and for sterilization of FDG in the final container. The pH for sterilizing FDG solutions must be slightly acidic to avoid decomposition. A pH of 5.5 appears to be optimal and gives FDG of very high radiochemical purity ({approx}99%). In addition, radiolysis of FDG in solutions of high activity concentration was significantly lower at pH 5.5 than at neutral pH. Conclusion: Terminal sterilization enables the production of FDG in full compliance with GMP-regulations even in Class C or D (US class 10,000 or 100,000) laboratories.

  5. Distributed acoustic sensing for pipeline monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Hill, David; McEwen-King, Magnus [OptaSense, QinetiQ Ltd., London (United Kingdom)

    2009-07-01

    Optical fibre is deployed widely across the oil and gas industry. As well as being deployed regularly to provide high bandwidth telecommunications and infrastructure for SCADA it is increasingly being used to sense pressure, temperature and strain along buried pipelines, on subsea pipelines and downhole. In this paper we present results from the latest sensing capability using standard optical fibre to detect acoustic signals along the entire length of a pipeline. In Distributed Acoustic Sensing (DAS) an optical fibre is used for both sensing and telemetry. In this paper we present results from the OptaSense{sup TM} system which has been used to detect third party intervention (TPI) along buried pipelines. In a typical deployment the system is connected to an existing standard single-mode fibre, up to 50km in length, and was used to independently listen to the acoustic / seismic activity at every 10 meter interval. We will show that through the use of advanced array processing of the independent, simultaneously sampled channels it is possible to detect and locate activity within the vicinity of the pipeline and through sophisticated acoustic signal processing to obtain the acoustic signature to classify the type of activity. By combining spare fibre capacity in existing buried fibre optic cables; processing and display techniques commonly found in sonar; and state-of-the-art in fibre-optic distributed acoustic sensing, we will describe the new monitoring capabilities that are available to the pipeline operator. Without the expense of retrofitting sensors to the pipeline, this technology can provide a high performance, rapidly deployable and cost effective method of providing gapless and persistent monitoring of a pipeline. We will show how this approach can be used to detect, classify and locate activity such as; third party interference (including activity indicative of illegal hot tapping); real time tracking of pigs; and leak detection. We will also show how an

  6. Combined Environment Acoustic Chamber (CEAC)

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The CEAC imposes combined acoustic, thermal and mechanical loads on aerospace structures. The CEAC is employed to measure structural response and determine...

  7. Increase in Naloxone Prescriptions Dispensed in US Retail Pharmacies Since 2013.

    Science.gov (United States)

    Jones, Christopher M; Lurie, Peter G; Compton, Wilson M

    2016-04-01

    Distribution of naloxone, traditionally through community-based naloxone programs, is a component of a comprehensive strategy to address the epidemic of prescription opioid and heroin overdose deaths in the United States. Recently, there has been increased focus on naloxone prescription in the outpatient setting, particularly through retail pharmacies, yet data on this practice are sparse. We found an 1170% increase in naloxone dispensing from US retail pharmacies between the fourth quarter of 2013 and the second quarter of 2015. These findings suggest that prescribing naloxone in the outpatient setting complements traditional community-based naloxone programs. PMID:26890174

  8. The study of neutron burst shape of a neutron tube driven by dispenser cathode

    Science.gov (United States)

    Grishnyaev, Evgeny; Polosatkin, Sergey

    2016-08-01

    A slim-shaped portable DD-neutron generator is developed at Budker institute of Nuclear Physics. The generator is a combination of Cockcroft-Walton voltage multiplier and a sealed gas-filled neutron tube driven by dispenser cathode. Neutron burst shape in pulsed mode of neutron tube operation is measured with stroboscopic time spectrometry, implemented on scintillation detector, and modeled with Comsol Script 1.3 and Comsol Multiphysics 3.5. Modeling appears to be in good agreement with experimental results. Measured pulse rise and fall times are 110 ns and 100 ns respectively.

  9. Evaluation of antibiotics dispensing profile in Tubarão, Santa Catarina, Brazil

    Directory of Open Access Journals (Sweden)

    Claudia Rauber

    2009-12-01

    Full Text Available Antibiotics are drugs widely used in prophylaxis and treatment of a great number of diseases. However, their use must be carefully controlled as acquisition in pharmacies, often without medical prescription, is elevated. The role of pharmacists in these circumstances is to practice dispensation in a rational manner. Through a structured questionnaire with open and closed questions, this study investigated the profile of antibiotics dispensed in pharmacies of Tubarão, Santa Catarina, Brazil. From the responses, it was observed that 85.0% dispense this class of medicine without medical prescription, mainly for treatment of respiratory (62.8% and urinary (12.0% tract disorders. Moreover, pharmacists' guidance was largely focused on posology (66.6% and drug interaction (12.6%, in addition to the interactions with contraceptives, alcohol and milk. The importance of avoiding antibiotics dispensation without medical prescription must be emphasized, as well as the benefits of educating the population to promote the rational use of medicines.Antibióticos são fármacos amplamente utilizados na profilaxia e no tratamento de grande número de doenças. Entretanto, seu uso deve ser cuidadosamente controlado nas farmácias, uma vez que nestas a aquisição sem prescrição médica é elevada. O papel dos farmacêuticos nessas circunstâncias é o de praticar a dispensação de maneira racional. Por meio de questionário estruturado, com questões abertas e fechadas, investigou-se o perfil dos antibióticos dispensados em farmácias de Tubarão, Santa Catarina, Brasil. Pelas respostas, observou-se que 85% das dispensa essa classe de medicamentos sem prescrição médica, principalmente para o tratamento de problemas dos tratos respiratório (62,8% e urinário (12,0%. Além disso, a orientação dos farmacêuticos se focou amplamente na posologia (66,6%e nas interações com fármacos (12,6%, em adição às interações com anticoncepcionais, álcool e

  10. A model for drug dispensing service based on the care process in the Brazilian health system

    Directory of Open Access Journals (Sweden)

    Luciano Soares

    2013-03-01

    Full Text Available Access to medication emphasizes the availability of the product at the expense of providing a service. The goal of this paper is to propose a theoretical model for a drug dispensing service, beginning with a reflection on the current realities of the Unified Health System and drug dispensation in Brazil. A conceptual analytical research made by a methodological course called disciplined imagination was mainly the approach applied to develop the model. The drug dispensing service is part of the care process, which considers access as an attribute; reception, connection and accountability, management, and clinical pharmaceutical aspects as components; and the rational use of drugs as the purpose. The proposed model addresses access to the dispensing service and demands a reorientation of routines, instruments, and practices.O acesso a medicamentos enfatiza a disponibilidade do produto em detrimento da provisão de um serviço. O objetivo deste trabalho é propor um modelo teórico para um serviço de dispensação de medicamentos, iniciando com uma reflexão sobre a realidade atual do Sistema Único de Saúde e a dispensação de medicamentos no Brasil. Uma pesquisa analítica conceitual realizada por meio de um percurso metodológico chamado de imaginação disciplinada constituiu a estratégia principal para o desenvolvimento do modelo. O serviço de dispensação é parte do processo de cuidado, o qual considera o acesso como um atributo; os aspectos acolhimento, vínculo e responsabilização, gestão e clínica farmacêutica como componentes e o uso racional de medicamentos como o propósito. O modelo proposto direciona o acesso para o serviço de dispensação e demanda a reorientação de rotinas, instrumentos e práticas.

  11. Development of an automated dispenser for the delivery of medicinal or vaccine-laden baits to raccoons (Procyon lotor).

    Science.gov (United States)

    Smyser, Timothy J; Redding, James V; Bevis, Crystal M; Page, L Kristen; Swihart, Robert K

    2015-04-01

    Medicinal baits are distributed to manage zoonotic diseases, including raccoon (Procyon lotor) rabies, but efficient distribution strategies are needed for suburban environments. We developed an automated dispenser that transfers fishmeal polymer baits at user-specified intervals from a magazine to a receptacle fitted with a filter that exploits raccoon dexterity to limit consumption by nontarget species. We introduce the concept of automated dispensers and describe bait removal success rates for raccoons versus nontarget species. We monitored visitation with remote cameras after deploying a dispenser, programmed to present two baits per night, in three disjunct forest patches in northwest Indiana. Raccoons removed 72% of baits; nontarget, white-footed mice (Peromyscus leucopus) removed 11%; Virginia opossums (Didelphis virginiana) removed 9%. Bait removal success varied significantly between raccoons (76%) and opossums (21%), improving bait delivery specificity relative to hand baiting. Accumulation of baits in receptacles resulted in excess (more than one) bait consumption (39% of baits consumed by raccoons were excess), suggesting design improvements are needed to present additional baits only after previous baits have been consumed. Automated dispensers successfully sustained bait availability throughout the operational period. Subsequent research is needed to determine whether a sustained availability of baits achieved with automated dispensers is more effective for the treatment of raccoons in suburban environments than traditional distribution methods. PMID:25647587

  12. A Review of the Anthropometric Characteristics, Grading and Dispensation of Junior and Youth Rugby Union Players in Australia.

    Science.gov (United States)

    Patton, Declan Alexander; McIntosh, Andrew Stuart; Denny, Greg

    2016-08-01

    The grading of Australian junior and youth rugby union players has received substantial media attention in recent years. Media reports have focussed on size mismatches observed between players, especially players with Polynesian heritage, and the concerned parents who fear for the safety of their child owing to perceived mismatches. Although such concerns are well meaning, few media reports recognise the need for substantial evidence to determine the best grading system for junior and youth rugby union players. The current study reviewed relevant literature pertinent to the grading and dispensation of junior and youth rugby union players. Using primary and secondary search strategies, a total of 33 articles reporting the anthropometric characteristics of junior and youth rugby players were identified. Anthropometric data from the literature were compared with normative population data and currently used dispensation criteria. Junior and youth rugby players were found to be taller and heavier than normative population data. Current dispensation criteria, in terms of body mass, were found to vary and it is suggested that criteria be revised and standardised across rugby unions throughout Australia. Although it is acknowledged that other factors are important for grading players, anthropometric characteristics should be considered as potential dispensation criteria to supplement current age-based grading for junior and youth rugby union players. Measuring the body mass and stature of each junior player upon pre-season registration is suggested, which would provide data to establish valid dispensation criteria for the following season. PMID:26886476

  13. Safety of dispensing prescribed iron formulation in childresistant containers among pharmacies in Saudi Arabia: a cross-sectional survey

    Directory of Open Access Journals (Sweden)

    Nahar Alruwaili

    2013-04-01

    Full Text Available Iron overdose remains a significant public health threat to young children. Unit dose packaging of potent iron supplements is expected to reduce the frequency of severe pediatric iron overdose incidents. Interna - tional regulations require child-resistant iron packages. We aim to know if iron is dispensed in child-resistant containers (CRCs and to emphasize the importance of using them. A prospective cross-sectional observational study assessing the proper dispensing of ferrous sulfate tablets in CRCs from major city pharmacies. Forty government and private pharmacies were visited. Ferrous sulfates with a total of 600 to 6500 mg elemental iron per package were found. The package of 6000 mg was the most commonly found. Most of the packages with high concentrations are dispensed from the government hospitals and primary healthcare centers pharmacies. None of the pharmacies dispensed iron in CRCs. To conclude, pharmacies dispensed iron in non-CRCs. Public health efforts on increasing awareness and improving packaging are highly needed. Authority regulations to use child-resistant iron packaging are required.

  14. Fluids and Combustion Facility Acoustic Emissions Controlled by Aggressive Low-Noise Design Process

    Science.gov (United States)

    Cooper, Beth A.; Young, Judith A.

    2004-01-01

    The Fluids and Combustion Facility (FCF) is a dual-rack microgravity research facility that is being developed by Northrop Grumman Information Technology (NGIT) for the International Space Station (ISS) at the NASA Glenn Research Center. As an on-orbit test bed, FCF will host a succession of experiments in fluid and combustion physics. The Fluids Integrated Rack (FIR) and the Combustion Integrated Rack (CIR) must meet ISS acoustic emission requirements (ref. 1), which support speech communication and hearing-loss-prevention goals for ISS crew. To meet these requirements, the NGIT acoustics team implemented an aggressive low-noise design effort that incorporated frequent acoustic emission testing for all internal noise sources, larger-scale systems, and fully integrated racks (ref. 2). Glenn's Acoustical Testing Laboratory (ref. 3) provided acoustical testing services (see the following photograph) as well as specialized acoustical engineering support as part of the low-noise design process (ref. 4).

  15. Opticians, Dispensing

    Science.gov (United States)

    ... More Sources of Data Publications Latest Publications » The Economics Daily Monthly Labor Review Beyond the Numbers Spotlight on Statistics Reports & Bulletins Commissioner's Corner Career Outlook Occupational Outlook Handbook Handbook of Methods Research Papers Copyright Information Contact & ...

  16. Modifying the acoustic impedance of polyurea-based composites

    Science.gov (United States)

    Nantasetphong, Wiroj; Amirkhizi, Alireza V.; Jia, Zhanzhan; Nemat-Nasser, Sia

    2013-04-01

    Acoustic impedance is a material property that depends on mass density and acoustic wave speed. An impedance mismatch between two media leads to the partial reflection of an acoustic wave sent from one medium to another. Active sonar is one example of a useful application of this phenomenon, where reflected and scattered acoustic waves enable the detection of objects. If the impedance of an object is matched to that of the surrounding medium, however, the object may be hidden from observation (at least directly) by sonar. In this study, polyurea composites are developed to facilitate such impedance matching. Polyurea is used due to its excellent blast-mitigating properties, easy casting, corrosion protection, abrasion resistance, and various uses in current military technology. Since pure polyurea has impedance higher than that of water (the current medium of interest), low mass density phenolic microballoon particles are added to create composite materials with reduced effective impedances. The volume fraction of particles is varied to study the effect of filler quantity on the acoustic impedance of the resulting composite. The composites are experimentally characterized via ultrasonic measurements. Computational models based on the method of dilute-randomly-distributed inclusions are developed and compared with the experimental results. These experiments and models will facilitate the design of new elastomeric composites with desirable acoustic impedances.

  17. Acoustic transparency and slow sound using detuned acoustic resonators

    DEFF Research Database (Denmark)

    Santillan, Arturo Orozco; Bozhevolnyi, Sergey I.

    2011-01-01

    We demonstrate that the phenomenon of acoustic transparency and slowsound propagation can be realized with detuned acoustic resonators (DAR), mimicking thereby the effect of electromagnetically induced transparency (EIT) in atomic physics. Sound propagation in a pipe with a series of side...

  18. Acoustic Emission Analysis Applet (AEAA) Software

    Science.gov (United States)

    Nichols, Charles T.; Roth, Don J.

    2013-01-01

    NASA Glenn Research and NASA White Sands Test Facility have developed software supporting an automated pressure vessel structural health monitoring (SHM) system based on acoustic emissions (AE). The software, referred to as the Acoustic Emission Analysis Applet (AEAA), provides analysts with a tool that can interrogate data collected on Digital Wave Corp. and Physical Acoustics Corp. software using a wide spectrum of powerful filters and charts. This software can be made to work with any data once the data format is known. The applet will compute basic AE statistics, and statistics as a function of time and pressure (see figure). AEAA provides value added beyond the analysis provided by the respective vendors' analysis software. The software can handle data sets of unlimited size. A wide variety of government and commercial applications could benefit from this technology, notably requalification and usage tests for compressed gas and hydrogen-fueled vehicles. Future enhancements will add features similar to a "check engine" light on a vehicle. Once installed, the system will ultimately be used to alert International Space Station crewmembers to critical structural instabilities, but will have little impact to missions otherwise. Diagnostic information could then be transmitted to experienced technicians on the ground in a timely manner to determine whether pressure vessels have been impacted, are structurally unsound, or can be safely used to complete the mission.

  19. Taming Acoustic Cavitation

    CERN Document Server

    Rivas, David Fernandez; Enriquez, Oscar R; Versluis, Michel; Prosperetti, Andrea; Gardeniers, Han; Lohse, Detlef

    2012-01-01

    In this fluid dynamics video we show acoustic cavitation occurring from pits etched on a silicon surface. By immersing the surface in a liquid, gas pockets are entrapped in the pits which upon ultrasonic insonation, are observed to shed cavitation bubbles. Modulating the driving pressure it is possible to induce different behaviours based on the force balance that determines the interaction among bubbles and the silicon surface. This system can be used for several applications like sonochemical water treatment, cleaning of surfaces with deposited materials such as biofilms.

  20. Lecture Notes On Acoustics

    International Nuclear Information System (INIS)

    This book mentions string vibration and wave, one-dimension wave and wave equation, characteristic impedance, governing equation of string, and wave energy from string, wave equation of wave and basic physical quantity like one-dimension wave equation, sound unit, sound intensity and energy, sound movement in a surface of discontinuity with transmission loss of sound by partition, and Snell's law, radiation, scatter and diffraction and sound in closed space with Sabine's theory, sound characteristic of closed space and duct acoustics.

  1. Dynamic acoustic tractor beams

    Energy Technology Data Exchange (ETDEWEB)

    Mitri, F. G., E-mail: F.G.Mitri@ieee.org [Chevron, Area 52 Technology – ETC, Santa Fe, New Mexico 87508 (United States)

    2015-03-07

    Pulling a sphere and vibrating it around an equilibrium position by amplitude-modulation in the near-field of a single finite circular piston transducer is theoretically demonstrated. Conditions are found where a fluid hexane sphere (with arbitrary radius) chosen as an example, centered on the axis of progressive propagating waves and submerged in non-viscous water, experiences an attractive (steady) force pulling it towards the transducer, as well as an oscillatory force forcing it to vibrate back-and-forth. Numerical predictions for the dynamic force illustrate the theory and suggest an innovative method in designing dynamic acoustical tractor beams.

  2. Dynamic acoustic tractor beams

    Science.gov (United States)

    Mitri, F. G.

    2015-03-01

    Pulling a sphere and vibrating it around an equilibrium position by amplitude-modulation in the near-field of a single finite circular piston transducer is theoretically demonstrated. Conditions are found where a fluid hexane sphere (with arbitrary radius) chosen as an example, centered on the axis of progressive propagating waves and submerged in non-viscous water, experiences an attractive (steady) force pulling it towards the transducer, as well as an oscillatory force forcing it to vibrate back-and-forth. Numerical predictions for the dynamic force illustrate the theory and suggest an innovative method in designing dynamic acoustical tractor beams.

  3. Prototype of a Questionnaire and Quiz System for Supporting Increase of Health Awareness During Wait Time in Dispensing Pharmacy

    Science.gov (United States)

    Toda, Takeshi; Chen, Poa-Min; Ozaki, Shinya; Ideguchi, Naoko; Miyaki, Tomoko; Nanbu, Keiko; Ikeda, Keiko

    For quit-smoking clinic and its campaign, there was a need for pharmacists to investigate pediatric patient's parent consciousness to tobacco harm utilizing wait time in a pediatric dispensing pharmacy. In this research, we developed the questionnaire and quiz total system using the tablet for user interface, in which people can easily answer the questionnaire/quiz and quickly see the total results on the spot in order to enhance their consciousness to the tobacco harm. The system also provides their tobacco dependence level based on the questionnaire results and some advice for their health and dietary habits due to the tobacco dependence level. From a field trial with one hundred four examinees in the pediatric dispensing pharmacy, the user interface was useful compared to conventional questionnaire form. The system could enhance their consciousness to tobacco harm and make their beneficial use of waiting time in dispensing pharmacy. Some interesting suggestions for improvement and new services were also obtained.

  4. Improving material-specific dispense processes for low-defect coatings

    Science.gov (United States)

    Brakensiek, Nick; Braggin, Jennifer; Berron, John; Ramirez, Raul; Anderson, Karl; Smith, Brian

    2011-04-01

    The drive to smaller, less expensive, and faster devices requires radical changes in material development. The increased material requirements drive complex processes that in turn drive equipment requirements. For the photolithography area this demand for improved materials is seen in growing requests for device level-specific tuning of organic bottom antireflective coatings (BARCs) or photoresists for certain imaging requirements, such as numerical aperture, immersion conditions, and optical parameters. To test and utilize the myriad of BARC materials, there is a need to install them on a coater-track quickly and efficiently. Installation typically requires a new filter installation, dispense line cleaning, and usually a minimum of 8-10 L of material to clear out bubbles and other nuisance defects before coating test wafers. As the number of materials increases, the ability to quickly prime a new filter becomes increasingly important. In this study, the Entegris IntelliGen® Mini dispense system was utilized to test various pump priming processes to ultimately minimize the volume purged to reach a defect baseline. In addition, the impacts of the filter media and filter retention on priming efficiency were studied. Results show that priming processes that were not matched to the filter in use could actually cause the defects to increase during the process, thus requiring additional purging to reach baseline, and thereby negating any time or volume savings. Properly programmed priming recipes reduced the purging time and the purging volume by 50-70%.

  5. Molecular epidemiology of a Pseudomonas aeruginosa hospital outbreak driven by a contaminated disinfectant-soap dispenser.

    Directory of Open Access Journals (Sweden)

    Simone Lanini

    Full Text Available BACKGROUND AND OBJECTIVE: Pseudomonas aeruginosa infection represents a main cause of morbidity and mortality among immunocompromised patients. This study describes a fatal epidemic of P. aeruginosa that occurred in a hematology unit in Italy. METHODS: Retrospective cohort study, prospective surveillance, auditing, extensive testing on healthcare workers and environmental investigation were performed to define the dynamics and potential causes of transmission. RAPD, macrorestriction analyses and sequence typing were used to define relationships between P. aeruginosa isolates. RESULTS: Eighteen cases of infection were identified in the different phases of the investigation. Of these, five constitute a significant molecular cluster of infection. A P. aeruginosa strain with the same genetic fingerprint and sequence type (ST175 as clinical isolates strain was also isolated from a heavily contaminated triclosan soap dispenser. DISCUSSION AND CONCLUSIONS: Our results are consistent with the hypothesis that patients became indirectly infected, e.g., during central venous catheter handling through contaminated items, and that the triclosan soap dispenser acted as a common continuous source of P. aeruginosa infection. Since P. aeruginosa is intrinsically unsusceptible to triclosan, the use of triclosan-based disinfectant formulations should be avoided in those healthcare settings hosting patients at high risk of P. aeruginosa infection.

  6. Improving material-specific dispense processes for low-defect coatings

    Science.gov (United States)

    Smith, Brian; Ramirez, Raul; Braggin, Jennifer; Wu, Aiwen; Anderson, Karl; Berron, John; Brakensiek, Nick; Washburn, Carlton

    2010-04-01

    Minimizing defects in spin-on lithography coatings requires a careful understanding of the interactions between the spin-on coating material and the filtration and dispense system used on the coating track. A wet-developable bottom anti-reflective coating (BARC) was examined for its interaction with polyamide and UPE media when utilizing the Entegris IntelliGen Mini dispense system. In addition, a new method of priming the filter and pump is described which improves the wetting of the filter media, preventing bubbles and other defect-generating air pockets within the system. The goal is to establish plumb-on procedures that are material and hardware specific to avoid any defect problems in the coating process, as well as to gain a better understanding of the chemical and physical interactions that lead to coating defects. Liquid particle counts from a laboratory-based filtration stand are compared with on-wafer defects from a commercial coating track to establish a correlation and allow better prediction of product performance. This comparison in turn will provide valuable insight to the engineering process of product filtration and bottling at the source.

  7. Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice.

    Directory of Open Access Journals (Sweden)

    Meredith H Shaffer

    Full Text Available BACKGROUND: Ezrin/radixin/moesin (ERM proteins are highly homologous proteins that function to link cargo molecules to the actin cytoskeleton. Ezrin and moesin are both expressed in mature lymphocytes, where they play overlapping roles in cell signaling and polarity, but their role in lymphoid development has not been explored. METHODOLOGY/PRINCIPAL FINDINGS: We characterized ERM protein expression in lymphoid tissues and analyzed the requirement for ezrin expression in lymphoid development. In wildtype mice, we found that most cells in the spleen and thymus express both ezrin and moesin, but little radixin. ERM protein expression in the thymus was differentially regulated, such that ezrin expression was highest in immature thymocytes and diminished during T cell development. In contrast, moesin expression was low in early thymocytes and upregulated during T cell development. Mice bearing a germline deletion of ezrin exhibited profound defects in the size and cellularity of the spleen and thymus, abnormal thymic architecture, diminished hematopoiesis, and increased proportions of granulocytic precursors. Further analysis using fetal liver chimeras and thymic transplants showed that ezrin expression is dispensable in hematopoietic and stromal lineages, and that most of the defects in lymphoid development in ezrin(-/- mice likely arise as a consequence of nutritional stress. CONCLUSIONS/SIGNIFICANCE: We conclude that despite high expression in lymphoid precursor cells, ezrin is dispensable for lymphoid development, most likely due to redundancy with moesin.

  8. Use of Six Sigma to improve pharmacist dispensing errors at an outpatient clinic.

    Science.gov (United States)

    Chan, Agnes L F

    2004-01-01

    Hospital pharmacists have been challenged to face the paradigm shift in their model of services in the 21st century in Taiwan. Patients are increasingly concerned about drug safety and medication errors. Because of the financial crisis of our national insurance bureau, pharmacists are required to care for more patients, use fewer resources, and work faster, better, and more efficiently than ever before while striving to enhance customer satisfaction and quality of care. Under these circumstances, patient safety needs to be a priority of pharmacists. According to a preliminary report on medication error announced by the nonofficial medication error reporting system, pharmacist dispensing error ranked second in the list of errors in Taiwan. In our drive to improve quality, reduce costs, and enhance financial performance, our department has tried the traditional quality-improvement strategy with varying degrees of success. We wanted to achieve a breakthrough result, hence we implemented Six-Sigma methodology. This program is the catalyst needed to combine quality, cost, and patient safety. This article describes our experience using Six-Sigma methodology to reduce dispensing error in our pharmacy department. PMID:15212318

  9. Japanese Community Pharmacists' Dispensing Influences Medicine Price Reduction more than Prescription Numbers.

    Science.gov (United States)

    Yokoi, Masayuki; Tashiro, Takao

    2016-01-01

    This study examined the economic efficiency of the separation of prescription and dispensation medicines between doctors in medical institutions and pharmacists in pharmacies. The separation system in Japanese prefectures was examined with publicly available data (Ministry of Health, Labour and Welfare, 2012-2014; retrieved from http://www.mhlw.go.jp/topics/medias/year). We investigated whether the separation system reduces the number of medicines or the medication cost of a prescription because of separating the economic management between prescribing and dispensing and the effect of mutual observation between doctors and pharmacists. It is optional for Japanese medical institutions to participate in the separation system. Consequently, the spreading rate of the separation system in each administrative district is highly variable. We examined the separation system effect using the National Healthcare Insurance data for three years, 2012-2014. We tested whether the separation system ratio for each prefecture was significantly correlated to the medication price or the number of medicines on a prescription. If spreading the separation system influenced the price of prescribed daily medications or the number of medicines, the correlation would be significant. As a result, the medication price was significantly negatively correlated with the separation system ratio, but the number of medicines was not significant. Therefore, the separation system was effective in reducing daily medication cost but had little influence on reducing the number of daily medicines. This was observed over three years in Japan. PMID:27157157

  10. Economic evaluation of task-shifting approaches to the dispensing of anti-retroviral therapy

    Directory of Open Access Journals (Sweden)

    Foster Nicola

    2012-09-01

    Full Text Available Abstract Background A scarcity of human resources for health has been identified as one of the primary constraints to the scale-up of the provision of Anti-Retroviral Treatment (ART. In South Africa there is a particularly severe lack of pharmacists. The study aims to compare two task-shifting approaches to the dispensing of ART: Indirectly Supervised Pharmacist’s Assistants (ISPA and Nurse-based pharmaceutical care models against the standard of care which involves a pharmacist dispensing ART. Methods A cross-sectional mixed methods study design was used. Patient exit interviews, time and motion studies, expert interviews and staff costs were used to conduct a costing from the societal perspective. Six facilities were sampled in the Western Cape province of South Africa, and 230 patient interviews conducted. Results The ISPA model was found to be the least costly task-shifting pharmaceutical model. However, patients preferred receiving medication from the nurse. This related to a fear of stigma and being identified by virtue of receiving ART at the pharmacy. Conclusions While these models are not mutually exclusive, and a variety of pharmaceutical care models will be necessary for scale up, it is useful to consider the impact of implementing these models on the provider, patient access to treatment and difficulties in implementation.

  11. Enhanced performance of dispenser printed MA n-type Bi₂Te₃ composite thermoelectric generators.

    Science.gov (United States)

    Madan, Deepa; Wang, Zuoqian; Chen, Alic; Juang, Rei-Cheng; Keist, Jay; Wright, Paul K; Evans, Jim W

    2012-11-01

    This work presents performance advancements of dispenser printed composite thermoelectric materials and devices. Dispenser printed thick films allow for low-cost and scalable manufacturing of microscale energy harvesting devices. A maximum ZT value of 0.31 has been achieved for mechanically alloyed (MA) n-type Bi₂Te₃-epoxy composite films with 1 wt % Se cured at 350 °C. The enhancement of ZT is a result of increase in the electrical conductivity through the addition of Se, which ultimately lowers the sintering temperature (350 °C). A 62 single-leg thermoelectric generator (TEG) prototype with 5 mm ×700 μm × 120 μm printed element dimensions was fabricated on a custom designed polyimide substrate with thick metal contacts. The prototype device produced a power output of 25 μW at 0.23 mA current and 109 mV voltage for a temperature difference of 20 °C, which is sufficient for low power generation for autonomous microsystem applications.

  12. Japanese Community Pharmacists’ Dispensing Influences Medicine Price Reduction more than Prescription Numbers

    Science.gov (United States)

    Yokoi, Masayuki; Tashiro, Takao

    2016-01-01

    This study examined the economic efficiency of the separation of prescription and dispensation medicines between doctors in medical institutions and pharmacists in pharmacies. The separation system in Japanese prefectures was examined with publicly available data (Ministry of Health, Labour and Welfare, 2012–2014; retrieved from http://www.mhlw.go.jp/topics/medias/year). We investigated whether the separation system reduces the number of medicines or the medication cost of a prescription because of separating the economic management between prescribing and dispensing and the effect of mutual observation between doctors and pharmacists. It is optional for Japanese medical institutions to participate in the separation system. Consequently, the spreading rate of the separation system in each administrative district is highly variable. We examined the separation system effect using the National Healthcare Insurance data for three years, 2012–2014. We tested whether the separation system ratio for each prefecture was significantly correlated to the medication price or the number of medicines on a prescription. If spreading the separation system influenced the price of prescribed daily medications or the number of medicines, the correlation would be significant. As a result, the medication price was significantly negatively correlated with the separation system ratio, but the number of medicines was not significant. Therefore, the separation system was effective in reducing daily medication cost but had little influence on reducing the number of daily medicines. This was observed over three years in Japan.

  13. Vital and dispensable roles of Plasmodium multidrug resistance transporters during blood- and mosquito-stage development.

    Science.gov (United States)

    Rijpma, Sanna R; van der Velden, Maarten; Annoura, Takeshi; Matz, Joachim M; Kenthirapalan, Sanketha; Kooij, Taco W A; Matuschewski, Kai; van Gemert, Geert-Jan; van de Vegte-Bolmer, Marga; Siebelink-Stoter, Rianne; Graumans, Wouter; Ramesar, Jai; Klop, Onny; Russel, Frans G M; Sauerwein, Robert W; Janse, Chris J; Franke-Fayard, Blandine M; Koenderink, Jan B

    2016-07-01

    Multidrug resistance (MDR) proteins belong to the B subfamily of the ATP Binding Cassette (ABC) transporters, which export a wide range of compounds including pharmaceuticals. In this study, we used reverse genetics to study the role of all seven Plasmodium MDR proteins during the life cycle of malaria parasites. Four P. berghei genes (encoding MDR1, 4, 6 and 7) were refractory to deletion, indicating a vital role during blood stage multiplication and validating them as potential targets for antimalarial drugs. Mutants lacking expression of MDR2, MDR3 and MDR5 were generated in both P. berghei and P. falciparum, indicating a dispensable role for blood stage development. Whereas P. berghei mutants lacking MDR3 and MDR5 had a reduced blood stage multiplication in vivo, blood stage growth of P. falciparum mutants in vitro was not significantly different. Oocyst maturation and sporozoite formation in Plasmodium mutants lacking MDR2 or MDR5 was reduced. Sporozoites of these P. berghei mutants were capable of infecting mice and life cycle completion, indicating the absence of vital roles during liver stage development. Our results demonstrate vital and dispensable roles of MDR proteins during blood stages and an important function in sporogony for MDR2 and MDR5 in both Plasmodium species. PMID:26991313

  14. Based on the acoustic emission technology Boiler "Four Tubes" leakage detection system%基于声发射技术的锅炉“四管”泄漏检测系统

    Institute of Scientific and Technical Information of China (English)

    张里阳

    2014-01-01

    针对电厂中锅炉“四管”泄漏时产生的广义声发射现象,对空间声场分布和声发射信号进行了分析研究。通过采集这种声发射信号并分析处理,建立了检测锅炉“四管”泄漏的检测系统,即锅炉炉管泄漏自动报警系统,给出了检测系统的软、硬件设计。该系统能够实现对锅炉炉管泄漏的早期测报,并判断出泄露的区域位置及泄漏程度,防止事故扩大,减少经济损失。%According to the power plant boiler "four tube" leakage in the generalized acoustic emission phenomenon, On the space sound field distribution and acoustic emission signal is studied. Through collecting and analyze the acoustic emission signal processing, detection is established boiler "four tube" leakage detection system, The boiler furnace tube leakage automatic alarm system, Detection system hardware and software design are also given in this paper. The system can realize early telemetry of boiler tube leakage, can realize early telemetry of boiler tube leakage, to prevent accidents, reduce economic loss.

  15. Acoustic Similarity and Dichotic Listening.

    Science.gov (United States)

    Benson, Peter

    1978-01-01

    An experiment tests conjectures that right ear advantage (REA) has an auditory origin in competition or interference between acoustically similar stimuli and that feature-sharing effect (FSE) has its origin in assignment of features of phonetically similar stimuli. No effect on the REA for acoustic similarity, and a clear effect of acoustic…

  16. Acoustic Center or Time Origin?

    DEFF Research Database (Denmark)

    Staffeldt, Henrik

    1999-01-01

    The paper discusses the acoustic center in relation to measurements of loudspeaker polar data. Also, it presents the related concept time origin and discusses the deviation that appears between positions of the acoustic center found by wavefront based and time based measuring methods....

  17. Digital Controller For Acoustic Levitation

    Science.gov (United States)

    Tarver, D. Kent

    1989-01-01

    Acoustic driver digitally controls sound fields along three axes. Allows computerized acoustic levitation and manipulation of small objects for such purposes as containerless processing and nuclear-fusion power experiments. Also used for controlling motion of vibration-testing tables in three dimensions.

  18. Propagation of Ion Acoustic Perturbations

    DEFF Research Database (Denmark)

    Pécseli, Hans

    1975-01-01

    Equations describing the propagation of ion acoustic perturbations are considered, using the assumption that the electrons are Boltzman distributed and isothermal at all times. Quasi-neutrality is also considered.......Equations describing the propagation of ion acoustic perturbations are considered, using the assumption that the electrons are Boltzman distributed and isothermal at all times. Quasi-neutrality is also considered....

  19. Acoustic array systems theory, implementation, and application

    CERN Document Server

    Bai, Mingsian R; Benesty, Jacob

    2013-01-01

    Presents a unified framework of far-field and near-field array techniques for noise source identification and sound field visualization, from theory to application. Acoustic Array Systems: Theory, Implementation, and Application provides an overview of microphone array technology with applications in noise source identification and sound field visualization. In the comprehensive treatment of microphone arrays, the topics covered include an introduction to the theory, far-field and near-field array signal processing algorithms, practical implementations, and common applic

  20. Time series analysis of fine particulate matter and asthma reliever dispensations in populations affected by forest fires

    Directory of Open Access Journals (Sweden)

    Elliott Catherine T

    2013-01-01

    Full Text Available Abstract Background Several studies have evaluated the association between forest fire smoke and acute exacerbations of respiratory diseases, but few have examined effects on pharmaceutical dispensations. We examine the associations between daily fine particulate matter (PM2.5 and pharmaceutical dispensations for salbutamol in forest fire-affected and non-fire-affected populations in British Columbia (BC, Canada. Methods We estimated PM2.5 exposure for populations in administrative health areas using measurements from central monitors. Remote sensing data on fires were used to classify the populations as fire-affected or non-fire-affected, and to identify extreme fire days. Daily counts of salbutamol dispensations between 2003 and 2010 were extracted from the BC PharmaNet database. We estimated rate ratios (RR and 95% confidence intervals (CIs for each population during all fire seasons and on extreme fire days, adjusted for temperature, humidity, and temporal trends. Overall effects for fire-affected and non-fire-affected populations were estimated via meta-regression. Results Fire season PM2.5 was positively associated with salbutamol dispensations in all fire-affected populations, with a meta-regression RR (95% CI of 1.06 (1.04-1.07 for a 10 ug/m3 increase. Fire season PM2.5 was not significantly associated with salbutamol dispensations in non-fire-affected populations, with a meta-regression RR of 1.00 (0.98-1.01. On extreme fire days PM2.5 was positively associated with salbutamol dispensations in both population types, with a global meta-regression RR of 1.07 (1.04 - 1.09. Conclusions Salbutamol dispensations were clearly associated with fire-related PM2.5. Significant associations were observed in smaller populations (range: 8,000 to 170,000 persons, median: 26,000 than those reported previously, suggesting that salbutamol dispensations may be a valuable outcome for public health surveillance during fire events.

  1. Prescription of potentially inappropriate medication in older persons in Switzerland: does the dispensing channel make a difference?

    Directory of Open Access Journals (Sweden)

    Blozik E

    2015-04-01

    Full Text Available Eva Blozik,1,2 Roland Rapold,1 Oliver Reich1 1Department of Health Sciences, Helsana Group, Zürich, Switzerland; 2Department of Medicine, Division of General Practice, University Medical Centre Freiburg, Freiburg, Germany Background: Drugs can be supplied either directly from the prescribing physician (physician dispensing [PD] or via a pharmacy. It is unclear whether the dispensing channel is associated with quality problems. Potentially inappropriate medication (PIM is associated with adverse outcomes in older persons and can be considered a marker for quality deficits in prescribing. We investigated whether prevalence of PIM differs across dispensing channels. Patients and methods: We analyzed basic health insurance claims of 50,747 person quarter years with PIM use of residents of the Swiss cantons Aargau and Lucerne of the years 2012 and 2013. PIM was identified using the Beers 2012 criteria and the PRISCUS list. We calculated PIM prevalence stratified by supply channel. Adjusted mixed effects logistic regression analysis was done to estimate the effect of obtaining medications through the dispensing physician as compared to the pharmacy channel on receipt of PIM. The most frequent PIMs were identified. Results: There is a small but detectable difference in total PIM prevalence: 30.7% of the population supplied by a dispensing physician as opposed to 29.3% individuals who received medication in a pharmacy. According to adjusted logistic regression individuals who obtained the majority of their medications from their prescribing physician had a 15% higher chance to receive a PIM (odds ratio 1.15, 95% confidence interval 1.08–1.22; P<0.001. Conclusion: Physician dispensing seems to affect quality and safety of drug prescriptions. Quality issues should not be neglected in the political discussion about the regulations on PD. Future studies should explore whether PD is related to other indicators of inefficiency or quality flaws. The present

  2. MEMS Based Acoustic Array

    Science.gov (United States)

    Sheplak, Mark (Inventor); Nishida, Toshikaza (Inventor); Humphreys, William M. (Inventor); Arnold, David P. (Inventor)

    2006-01-01

    Embodiments of the present invention described and shown in the specification aid drawings include a combination responsive to an acoustic wave that can be utilized as a dynamic pressure sensor. In one embodiment of the present invention, the combination has a substrate having a first surface and an opposite second surface, a microphone positioned on the first surface of the substrate and having an input and a first output and a second output, wherein the input receives a biased voltage, and the microphone generates an output signal responsive to the acoustic wave between the first output and the second output. The combination further has an amplifier positioned on the first surface of the substrate and having a first input and a second input and an output, wherein the first input of the amplifier is electrically coupled to the first output of the microphone and the second input of the amplifier is electrically coupled to the second output of the microphone for receiving the output sinual from the microphone. The amplifier is spaced from the microphone with a separation smaller than 0.5 mm.

  3. Acoustics and Hearing

    CERN Document Server

    Damaske, Peter

    2008-01-01

    When one listens to music at home, one would like to have an acoustic impression close to that of being in the concert hall. Until recently this meant elaborate multi-channelled sound systems with 5 or more speakers. But head-related stereophony achieves the surround-sound effect in living rooms with only two loudspeakers. By virtue of their slight directivity as well as an electronic filter the limitations previously common to two-speaker systems can be overcome and this holds for any arbitrary two-channel recording. The book also investigates the question of how a wide and diffuse sound image can arise in concert halls and shows that the quality of concert halls decisively depends on diffuse sound images arising in the onset of reverberation. For this purpose a strong onset of reverberation is modified in an anechoic chamber by electroacoustic means. Acoustics and Hearing proposes ideas concerning signal processing in the auditory system that explain the measured results and the resultant sound effects plea...

  4. Acoustic data transmission method

    Energy Technology Data Exchange (ETDEWEB)

    Duckworth, A.

    1991-09-17

    This patent describes a method for transmitting time line data through a drillstring having drill pipe sections connected end-to-end by joints from a first location below the surface of the earth to a second location at or near the surface of the earth, the length and cross-sectional area of the drill pipe sections being different from the length and cross-sectional area of the joints. It comprises generating acoustic data signals having a single frequency content in at least one passband of the drillstring; transmitting the data signals through the drillstring from either the first location to the second location or from the second location to the first location during a time period prior to the onset of reflective interference caused by the data signals reflecting from along the length of the drillstring, the time period being equal to or less than the time for the data signals to travel three lengths of the drillstring; stopping the transmission of data signals at the onset of the reflective interference and allowing the acoustic signals to substantially attenuate; and detecting the data signals at the respective first or second location.

  5. Randomized crossover study evaluating the effect of a hand sanitizer dispenser on the frequency of hand hygiene among anesthesiology staff in the operating room.

    Science.gov (United States)

    Munoz-Price, L Silvia; Patel, Zalak; Banks, Shawn; Arheart, Kristopher; Eber, Scott; Lubarsky, David A; Birnbach, David J

    2014-06-01

    Forty anesthesia providers were evaluated with and without hand sanitizer dispensers present on the anesthesia machine. Having a dispenser increased the frequency of hand hygiene only from 0.5 to 0.8 events per hour (P = .01). Other concomitant interventions are needed to further increase hand hygiene frequency among anesthesia providers. PMID:24799649

  6. 声发射技术在钢包耳轴环形焊缝安全检测中的应用%On the way to safety detect the circumferential welds for a steel ladle trunnion by using the acoustic emission technology

    Institute of Scientific and Technical Information of China (English)

    张维刚; 徐彦廷; 王强; 叶荣耀; 何鹏君

    2013-01-01

    钢包耳轴焊缝缺陷是影响钢包安全运行的重大危险源,常规检测手段无法探测耳轴根部的疲劳裂纹.利用声发射平面定位技术对钢包耳轴焊缝进行检测,对检测数据进行滤波,以确定目标信号.利用希尔伯特-黄变换对目标信号进行EMD分解,对分解后的8个本征模态函数进行傅里叶变换,以确定其频率范围.结果表明,声发射技术对形状复杂的大型设备的结构完整性检测有独特优势.%The present paper is to introduce a method on how to detect the circumferential welding defects for a steel ladle trunnion by using the acoustic emission technology.As is known,ladles are essential part to move liquid metals at high temperature in metallurgical works.However,the defects in trunnion welds of a steel ladle always tend to be major hazard sources leading to the safe operation of the ladles.But the conventional detection method can hardly find the fatigue cracks in the trunnion root.It is for this reason that we have been working at the problem and proposed a scheme that acoustic emission plannar location technology can be used for the job in this paper.The given method we have developed can be used to examine the behavior of material deformation under stress by using the Acoustic Emission (AE) testing,which can be used as a nondestructive means for finding the defects in the structural proof testing and plant operation.Our method is to use the SAMOS AE system,in which the testing device is a technologically advanced system based on PAC's PCI -8 Acoustic Emission and can be made highly exciting or stimulating.The method has been developed working at a low power,low bandwidth and multiple channels.The SAMOS AE system we have proposed is working through the process of collecting incoming hits into events & analyzing the entering times of the hits in an event to produce a source location.In the process,the data filtering has been done to find the target signals.The results of

  7. Failure Mechanism of Rock Bridge Based on Acoustic Emission Technique

    OpenAIRE

    Guoqing Chen; Yan Zhang; Runqiu Huang; Fan Guo; Guofeng Zhang

    2015-01-01

    Acoustic emission (AE) technique is widely used in various fields as a reliable nondestructive examination technology. Two experimental tests were carried out in a rock mechanics laboratory, which include (1) small scale direct shear tests of rock bridge with different lengths and (2) large scale landslide model with locked section. The relationship of AE event count and record time was analyzed during the tests. The AE source location technology and comparative analysis with its actual failu...

  8. Acoustic tests of Lorentz symmetry using Bulk Acoustic Wave quartz oscillators

    CERN Document Server

    Goryachev, M; Haslinger, Ph; Mizrachi, E; Anderegg, L; Müller, H; Hohensee, M; Tobar, M E

    2016-01-01

    A new method of probing Lorentz invariance in the neutron sector is described. The method is baed on stable quartz bulk acoustic wave oscillators compared on a rotating table. Due to Lorentz-invariance violation, the resonance frequencies of acoustic wave resonators depend on the direction in space via a corresponding dependence of masses of the constituent elements of solids. This dependence is measured via observation of oscillator phase noise built around such devices. The first such experiment now shows sensitivity to violation down to the limit $\\tilde{c}^n_Q=(-1.8\\pm2.2)\\times 10^{-14}$ GeV. Methods to improve the sensitivity are described together with some other applications of the technology in tests of fundamental physics.

  9. Optical Heterodyne Investigation of the Microwave Frequency Acoustic Properties of Liquids.

    Science.gov (United States)

    Bonney, Rob

    An optical heterodyne interferometer with a state -of-the-art microwave frequency acoustic transducer was used to measure the acoustic properties of liquids and solutions at frequencies up to 1.5 GHz. Heterodyne detection with a strong optical local oscillator was used to detect a weak optical signal beam produced by Bragg deflection from an acoustic wave coupled into a liquid sample. The acoustic transducer had a frequency range of 0.2-1.5 GHz. Several liquid mixtures were measured for the first time, including aqueous dimethyl sulfoxide, and ethyl acetate in carbon disulphide. In some cases, previously unknown dispersions were characterized. A thermodynamic model (valid in the low frequency limit) involving the heat of mixing was used successfully to predict the variation of velocity with composition of liquid mixtures. With this model as a guide, an attempt was made to identify a liquid mixture which would make a superior medium for the acoustic microscope. The search produced results which supported theoretical predictions, but no superior medium was found. Solutions of biomolecules were also investigated due to interest in possible resonant acoustic modes in DNA. No dispersions or resonances were found in solutions of polyglycines, and results for DNA solutions were inconclusive. Applications of this work include general studies in liquid acoustics at very high frequencies, acoustic studies of DNA solutions, and characterization of media for such technological applications as acoustic microscopy or phase conjugation using stimulated Brillouin scattering.

  10. Experimental verification of theoretical equations for acoustic radiation force on compressible spherical particles in traveling waves

    Science.gov (United States)

    Johnson, Kennita A.; Vormohr, Hannah R.; Doinikov, Alexander A.; Bouakaz, Ayache; Shields, C. Wyatt; López, Gabriel P.; Dayton, Paul A.

    2016-05-01

    Acoustophoresis uses acoustic radiation force to remotely manipulate particles suspended in a host fluid for many scientific, technological, and medical applications, such as acoustic levitation, acoustic coagulation, contrast ultrasound imaging, ultrasound-assisted drug delivery, etc. To estimate the magnitude of acoustic radiation forces, equations derived for an inviscid host fluid are commonly used. However, there are theoretical predictions that, in the case of a traveling wave, viscous effects can dramatically change the magnitude of acoustic radiation forces, which make the equations obtained for an inviscid host fluid invalid for proper estimation of acoustic radiation forces. To date, experimental verification of these predictions has not been published. Experimental measurements of viscous effects on acoustic radiation forces in a traveling wave were conducted using a confocal optical and acoustic system and values were compared with available theories. Our results show that, even in a low-viscosity fluid such as water, the magnitude of acoustic radiation forces is increased manyfold by viscous effects in comparison with what follows from the equations derived for an inviscid fluid.

  11. Acoustic Signal Feature Extraction of Vehicle Targets

    Institute of Scientific and Technical Information of China (English)

    蓝金辉; 马宝华; 李科杰

    2002-01-01

    Acoustic signal feature extraction is an important part of target recognition. The mechanisms for producing acoustic signals and their propagation are analyzed to extract the features of the radiated noise from different targets. Analysis of the acoustic spectra of typical vehicle targets acquired outdoors shows that the vehicles can be classified based on the acoustic spectra and amplitudes.

  12. Acoustic emission testing

    CERN Document Server

    Grosse, Christian U

    2008-01-01

    Acoustic Emission (AE) techniques have been studied in civil engineering for a long time. The techniques are recently going to be more and more applied to practical applications and to be standardized in the codes. This is because the increase of aging structures and disastrous damages due to recent earthquakes urgently demand for maintenance and retrofit of civil structures in service for example. It results in the need for the development of advanced and effective inspection techniques. Thus, AE techniques draw a great attention to diagnostic applications and in material testing. The book covers all levels from the description of AE basics for AE beginners (level of a student) to sophisticated AE algorithms and applications to real large-scale structures as well as the observation of the cracking process in laboratory specimen to study fracture processes.

  13. Electrically Controllable Microparticle Synthesis and Digital Microfluidic Manipulation by Electric-Field-Induced Droplet Dispensing into Immiscible Fluids.

    Science.gov (United States)

    Um, Taewoong; Hong, Jiwoo; Im, Do Jin; Lee, Sang Joon; Kang, In Seok

    2016-01-01

    The dispensing of tiny droplets is a basic and crucial process in a myriad of applications, such as DNA/protein microarray, cell cultures, chemical synthesis of microparticles, and digital microfluidics. This work systematically demonstrates droplet dispensing into immiscible fluids through electric charge concentration (ECC) method. It exhibits three main modes (i.e., attaching, uniform, and bursting modes) as a function of flow rates, applied voltages, and gap distances between the nozzle and the oil surface. Through a conventional nozzle with diameter of a few millimeters, charged droplets with volumes ranging from a few μL to a few tens of nL can be uniformly dispensed into the oil chamber without reduction in nozzle size. Based on the features of the proposed method (e.g., formation of droplets with controllable polarity and amount of electric charge in water and oil system), a simple and straightforward method is developed for microparticle synthesis, including preparation of colloidosomes and fabrication of Janus microparticles with anisotropic internal structures. Finally, a combined system consisting of ECC-induced droplet dispensing and electrophoresis of charged droplet (ECD)-driven manipulation systems is constructed. This integrated platform will provide increased utility and flexibility in microfluidic applications because a charged droplet can be delivered toward the intended position by programmable electric control. PMID:27534580

  14. 21 CFR 1300.04 - Definitions relating to the dispensing of controlled substances by means of the Internet.

    Science.gov (United States)

    2010-04-01

    ... controlled substances by means of the Internet. 1300.04 Section 1300.04 Food and Drugs DRUG ENFORCEMENT... substances by means of the Internet. (a) Any term not defined in this part or elsewhere in this chapter shall... evaluation of the patient. (c) The term deliver, distribute, or dispense by means of the Internet...

  15. Electrically Controllable Microparticle Synthesis and Digital Microfluidic Manipulation by Electric-Field-Induced Droplet Dispensing into Immiscible Fluids

    Science.gov (United States)

    Um, Taewoong; Hong, Jiwoo; Im, Do Jin; Lee, Sang Joon; Kang, In Seok

    2016-08-01

    The dispensing of tiny droplets is a basic and crucial process in a myriad of applications, such as DNA/protein microarray, cell cultures, chemical synthesis of microparticles, and digital microfluidics. This work systematically demonstrates droplet dispensing into immiscible fluids through electric charge concentration (ECC) method. It exhibits three main modes (i.e., attaching, uniform, and bursting modes) as a function of flow rates, applied voltages, and gap distances between the nozzle and the oil surface. Through a conventional nozzle with diameter of a few millimeters, charged droplets with volumes ranging from a few μL to a few tens of nL can be uniformly dispensed into the oil chamber without reduction in nozzle size. Based on the features of the proposed method (e.g., formation of droplets with controllable polarity and amount of electric charge in water and oil system), a simple and straightforward method is developed for microparticle synthesis, including preparation of colloidosomes and fabrication of Janus microparticles with anisotropic internal structures. Finally, a combined system consisting of ECC-induced droplet dispensing and electrophoresis of charged droplet (ECD)-driven manipulation systems is constructed. This integrated platform will provide increased utility and flexibility in microfluidic applications because a charged droplet can be delivered toward the intended position by programmable electric control.

  16. Electrically Controllable Microparticle Synthesis and Digital Microfluidic Manipulation by Electric-Field-Induced Droplet Dispensing into Immiscible Fluids

    Science.gov (United States)

    Um, Taewoong; Hong, Jiwoo; Im, Do Jin; Lee, Sang Joon; Kang, In Seok

    2016-01-01

    The dispensing of tiny droplets is a basic and crucial process in a myriad of applications, such as DNA/protein microarray, cell cultures, chemical synthesis of microparticles, and digital microfluidics. This work systematically demonstrates droplet dispensing into immiscible fluids through electric charge concentration (ECC) method. It exhibits three main modes (i.e., attaching, uniform, and bursting modes) as a function of flow rates, applied voltages, and gap distances between the nozzle and the oil surface. Through a conventional nozzle with diameter of a few millimeters, charged droplets with volumes ranging from a few μL to a few tens of nL can be uniformly dispensed into the oil chamber without reduction in nozzle size. Based on the features of the proposed method (e.g., formation of droplets with controllable polarity and amount of electric charge in water and oil system), a simple and straightforward method is developed for microparticle synthesis, including preparation of colloidosomes and fabrication of Janus microparticles with anisotropic internal structures. Finally, a combined system consisting of ECC-induced droplet dispensing and electrophoresis of charged droplet (ECD)-driven manipulation systems is constructed. This integrated platform will provide increased utility and flexibility in microfluidic applications because a charged droplet can be delivered toward the intended position by programmable electric control. PMID:27534580

  17. 76 FR 53154 - In the Matter of Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Notice...

    Science.gov (United States)

    2011-08-25

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION In the Matter of Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Notice... Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International...

  18. An electrode design for droplet dispensing with accurate volume in electro-wetting-based microfluidics

    Science.gov (United States)

    Wang, Wei; Chen, Jianfeng; Zhou, Jia

    2016-06-01

    Electro-wetting-on-dielectric actuation enables droplets, the basic units of digital microfluidics, to be manipulated on a two-dimensional surface, providing a versatile platform for chemical assays or multi-step operations at micro- or nano-scale. In this paper, we carry out characterization experiments to demonstrate an electrode design to improve the reproducibility of on-chip droplet generation with no extra external apparatus. The overall reproducibility for a sequence of droplets dispensed consecutively from a non-refilling reservoir can be limited within ±0.5%. Results from the repetition of 1000 iterations offer the long-term reproducibility in the range of ±1%, indicating its validity in practical applications.

  19. Catch-slip bonds can be dispensable for motor force regulation during skeletal muscle contraction

    Science.gov (United States)

    Dong, Chenling; Chen, Bin

    2015-07-01

    It is intriguing how multiple molecular motors can perform coordinated and synchronous functions, which is essential in various cellular processes. Recent studies on skeletal muscle might have shed light on this issue, where rather precise motor force regulation was partly attributed to the specific stochastic features of a single attached myosin motor. Though attached motors can randomly detach from actin filaments either through an adenosine triphosphate (ATP) hydrolysis cycle or through "catch-slip bond" breaking, their respective contribution in motor force regulation has not been clarified. Here, through simulating a mechanical model of sarcomere with a coupled Monte Carlo method and finite element method, we find that the stochastic features of an ATP hydrolysis cycle can be sufficient while those of catch-slip bonds can be dispensable for motor force regulation.

  20. A multiple-drawer medication layout problem in automated dispensing cabinets.

    Science.gov (United States)

    Pazour, Jennifer A; Meller, Russell D

    2012-12-01

    In this paper we investigate the problem of locating medications in automated dispensing cabinets (ADCs) to minimize human selection errors. We formulate the multiple-drawer medication layout problem and show that the problem can be formulated as a quadratic assignment problem. As a way to evaluate various medication layouts, we develop a similarity rating for medication pairs. To solve industry-sized problem instances, we develop a heuristic approach. We use hospital ADC transaction data to conduct a computational experiment to test the performance of our developed heuristics, to demonstrate how our approach can aid in ADC design trade-offs, and to illustrate the potential improvements that can be made when applying an analytical process to the multiple-drawer medication layout problem. Finally, we present conclusions and future research directions.

  1. Piezoelectric driven thermo-acoustic refrigerator

    Science.gov (United States)

    Chinn, D. G.; Nouh, M.; Aldraihem, O.; Baz, A.

    2011-03-01

    Thermoacoustic refrigeration is an emerging refrigeration technology which does not rely for in its operation on the use of any moving parts or harmful refrigerants. This technology uses acoustic waves to pump heat across a temperature gradient. The vast majority of thermoacoustic refrigerators to date have used electromagnetic loudspeakers to generate the acoustic input. In this paper, the design, construction, operation, and modeling of a piezoelectric-driven thermoacoustic refrigerator are detailed. This refrigerator demonstrates the effectiveness of piezoelectric actuation in moving 0.3 W of heat across an 18 degree C temperature difference with an input power of 7.6 W. The performance characteristics of this class of thermoacoustic-piezoelectric refrigerator are modeled using DeltaEC software and the predictions are validated experimentally. The obtained results confirm the validity of the developed model. Furthermore, the potential of piezoelectric actuation as effective means for driving thermoacoustic refrigerators is demonstrated as compared to the conventional electromagnetic loudspeakers which are heavy and require high actuation energy. The developed theoretical and experimental tools can serve as invaluable means for the design and testing of other piezoelectric driven thermoacoustic refrigerator configurations.

  2. Need and Role of Underwater Acoustic Sensor Networks

    Directory of Open Access Journals (Sweden)

    Tajinder Singh

    2013-07-01

    Full Text Available The field of underwater acoustic sensor networking is growing rapidly thanks to the key role it plays in many military and commercial applications. Among these are disaster prevention, tactical surveillance, offshore exploration, pollution monitoring and oceanographic data collection. Moreover, unmanned or autonomous underwater vehicles (UUVs, AUVs, equipped with sensors, will enable the exploration of natural undersea resources and gathering of scientific data in collaborative monitoring missions. Underwater acoustic networking is the enabling technology for these applications. The objective of this paper is to understand several fundamental key aspects of underwater acoustic communications. Different architectures for two-dimensional and three-dimensional underwater sensor networks are discussed, and the characteristics of the underwater channel are detailed. The main challenges for the development of efficient networking solutions posed by the underwater environment are detailed. This paper also presents a detailed explanation of the sensor networks used in tsunami detection. We then present an overview of the recent advances

  3. Acoustic spectroscopy: A powerful analytical method for the pharmaceutical field?

    Science.gov (United States)

    Bonacucina, Giulia; Perinelli, Diego R; Cespi, Marco; Casettari, Luca; Cossi, Riccardo; Blasi, Paolo; Palmieri, Giovanni F

    2016-04-30

    Acoustics is one of the emerging technologies developed to minimize processing, maximize quality and ensure the safety of pharmaceutical, food and chemical products. The operating principle of acoustic spectroscopy is the measurement of the ultrasound pulse intensity and phase after its propagation through a sample. The main goal of this technique is to characterise concentrated colloidal dispersions without dilution, in such a way as to be able to analyse non-transparent and even highly structured systems. This review presents the state of the art of ultrasound-based techniques in pharmaceutical pre-formulation and formulation steps, showing their potential, applicability and limits. It reports in a simplified version the theory behind acoustic spectroscopy, describes the most common equipment on the market, and finally overviews different studies performed on systems and materials used in the pharmaceutical or related fields. PMID:26976503

  4. Achieving acoustic cloak by using compressible background flow

    Science.gov (United States)

    Zhang, Ruo-Yang; Zhao, Qing; Ge, Mo-Lin

    2016-08-01

    We propose a scheme of acoustic spherical cloaking by means of background irrotational flow in compressible fluid. The background flow forms a virtual curved spacetime and directs the sound waves to bypass the cloaked objects. To satisfy the laws of real fluid, we show that spatially distributed mass source and momentum source are necessary to supply. The propagation of sound waves in this system is studied via both geometric acoustics approximation and full wave approach. The analytic solution of sound fields is obtained for plane wave incidence. The results reveal the effect of phase retardation (or lead) in comparison with the ordinary transformation-acoustic cloak. In addition, the ability of cloaking is also evaluated for unideal background flows by analyzing the scattering cross section. Project supported by the National Natural Science Foundation of China (Grant Nos. 11475088 and 11275024) and the Fund from the Ministry of Science and Technology of China (Grant No. 2013YQ030595-3).

  5. Teaching room acoustics as a product sound quality issue

    Science.gov (United States)

    Kleiner, Mendel; Vastfjall, Daniel

    2003-04-01

    The department of Applied Acoustics teaches engineering and architect students at Chalmers University of Technology. The teaching of room acoustics to architectural students has been under constant development under several years and is now based on the study of room acoustics as a product sound quality issue. Various listening sessions using binaural sound recording and reproduction is used to focus students' learning on simple, easy to remember concepts. Computer modeling using ray tracing software and auralization is also used extensively as a tool to demonstrate concepts in addition to other software for simple sound generation and manipulation. Sound in general is the focus of an interdisciplinary course for students from Chalmers as well as from a school of art, a school of design, and a school of music which offers particular challenges and which is almost all listening based.

  6. Acoustic evaluation of cementing quality using obliquely incident ultrasonic signals

    Institute of Scientific and Technical Information of China (English)

    Duan Wen-Xing; Qiao Wen-Xiao; Che Xiao-Hua; Xie Hui

    2014-01-01

    Ultrasonic cement bond logging is a widely used method for evaluating cementing quality. Conventional ultrasonic cement bond logging uses vertical incidence and cannot accurately evaluate lightweight cement bonding. Oblique incidence is a new technology for evaluating cement quality with improved accuracy for lightweight cements. In this study, we simulated models of acoustic impedance of cement and cementing quality using ultrasonic oblique incidence, and we obtained the relation between cementing quality, acoustic impedance of cement, and the acoustic attenuation coeffi cient of the A0-mode and S0-mode Lamb waves. Then, we simulated models of different cement thickness and we obtained the relation between cement thickness and the time difference of the arrival between the A0 and A0′ modes.

  7. Mating disruption of Planococcus ficus (Hemiptera: Pseudococcidae) in vineyards using reservoir pheromone dispensers.

    Science.gov (United States)

    Cocco, Arturo; Lentini, Andrea; Serra, Giuseppe

    2014-10-15

    Mating disruption field experiments to control the vine mealybug, Planococcus ficus (Signoret) (Hemiptera: Pseudococcidae), were carried out in 2008 and 2009 in two commercial vineyards in Sardinia (Italy). The effectiveness of mating disruption was evaluated by testing reservoir dispensers loaded with 100 mg (62.5 g/ha) and 150 mg (93.8 g/ha) of the sex pheromone in 2008 and 2009, respectively. The number of males captured in pheromone traps, the P. ficus population density and age structure, the parasitism rate, the percentage of ovipositing females, and the crop damage were compared between disrupted and untreated plots. In both field trials, the number of males captured in mating disruption plots was significantly reduced by 86% and 95%, respectively. Mating disruption at the initial dose of 62.5 g/ha of active ingredient gave inconclusive results, whereas the dose of 93.8 g/ha significantly lowered the mealybug density and modified the age structure, which showed a lower percentage of ovipositing females and a higher proportion of preovipositing females. Mating disruption did not affect negatively the parasitism rate, which was higher in the disrupted than in the control plots (>1.5-fold). Crop damage at harvest was very low in both field trials and did not differ between treatments. Mating disruption was effective in wide plots protected with dispensers loaded with 150 mg of the sex pheromone, showing its potential to be included in the overall integrated control programs in Mediterranean wine-growing regions.

  8. Completion of treatment for latent tuberculosis infection with monthly drug dispensation directly through the tuberculosis clinic.

    Directory of Open Access Journals (Sweden)

    Claudia C Dobler

    Full Text Available SETTING: An Australian metropolitan TB clinic where treatment for latent tuberculosis infection (LTBI comprises six months of isoniazid, self-administered but dispensed monthly by the clinic. OBJECTIVE: To determine the proportion of patients who complete treatment for LTBI and to identify factors associated with non-completion. METHODS: Clinical files of all patients receiving treatment for LTBI between 01/2000 and 12/2010 were reviewed. The study population comprised all patients who were commenced on isoniazid as treatment for LTBI. Odds ratios (OR for completing treatment were estimated by logistic regression. RESULTS: Of 216 patients who commenced isoniazid treatment for LTBI, 163 (75% completed six months treatment [corrected]. Fifty-three percent of the 53 patients who did not complete treatment dropped out after three months treatment. The mean (SD age of the patients was 27 (16 years and 123 (57% were female. The majority of patients (59% were born overseas and 69% received treatment for LTBI because they were contacts of patients with TB. Patients' sex, age, country of birth, time since immigration for overseas born people, health care worker status, TST conversion status, chest x-ray findings, language, employment status and the indication for which treatment of LTBI was prescribed were not significantly related to treatment completion. CONCLUSION: In a setting where isoniazid is dispensed monthly by the TB clinic, a relatively high proportion of patients who commence treatment for LTBI complete the six month scheduled course of treatment. The study did not identify any patient characteristics that predicted treatment completion. Interventions to improve completion rates should extend over the whole duration of treatment.

  9. Prelamin A and lamin A appear to be dispensable in the nuclear lamina.

    Science.gov (United States)

    Fong, Loren G; Ng, Jennifer K; Lammerding, Jan; Vickers, Timothy A; Meta, Margarita; Coté, Nathan; Gavino, Bryant; Qiao, Xin; Chang, Sandy Y; Young, Stephanie R; Yang, Shao H; Stewart, Colin L; Lee, Richard T; Bennett, C Frank; Bergo, Martin O; Young, Stephen G

    2006-03-01

    Lamin A and lamin C, both products of Lmna, are key components of the nuclear lamina. In the mouse, a deficiency in both lamin A and lamin C leads to slow growth, muscle weakness, and death by 6 weeks of age. Fibroblasts deficient in lamins A and C contain misshapen and structurally weakened nuclei, and emerin is mislocalized away from the nuclear envelope. The physiologic rationale for the existence of the 2 different Lmna products lamin A and lamin C is unclear, although several reports have suggested that lamin A may have particularly important functions, for example in the targeting of emerin and lamin C to the nuclear envelope. Here we report the development of lamin C-only mice (Lmna(LCO/LCO)), which produce lamin C but no lamin A or prelamin A (the precursor to lamin A). Lmna(LCO/LCO) mice were entirely healthy, and Lmna(LCO/LCO) cells displayed normal emerin targeting and exhibited only very minimal alterations in nuclear shape and nuclear deformability. Thus, at least in the mouse, prelamin A and lamin A appear to be dispensable. Nevertheless, an accumulation of farnesyl-prelamin A (as occurs with a deficiency in the prelamin A processing enzyme Zmpste24) caused dramatically misshapen nuclei and progeria-like disease phenotypes. The apparent dispensability of prelamin A suggested that lamin A-related progeroid syndromes might be treated with impunity by reducing prelamin A synthesis. Remarkably, the presence of a single Lmna(LCO) allele eliminated the nuclear shape abnormalities and progeria-like disease phenotypes in Zmpste24-/- mice. Moreover, treating Zmpste24-/- cells with a prelamin A-specific antisense oligonucleotide reduced prelamin A levels and significantly reduced the frequency of misshapen nuclei. These studies suggest a new therapeutic strategy for treating progeria and other lamin A diseases. PMID:16511604

  10. Effects of subsampling of passive acoustic recordings on acoustic metrics.

    Science.gov (United States)

    Thomisch, Karolin; Boebel, Olaf; Zitterbart, Daniel P; Samaran, Flore; Van Parijs, Sofie; Van Opzeeland, Ilse

    2015-07-01

    Passive acoustic monitoring is an important tool in marine mammal studies. However, logistics and finances frequently constrain the number and servicing schedules of acoustic recorders, requiring a trade-off between deployment periods and sampling continuity, i.e., the implementation of a subsampling scheme. Optimizing such schemes to each project's specific research questions is desirable. This study investigates the impact of subsampling on the accuracy of two common metrics, acoustic presence and call rate, for different vocalization patterns (regimes) of baleen whales: (1) variable vocal activity, (2) vocalizations organized in song bouts, and (3) vocal activity with diel patterns. To this end, above metrics are compared for continuous and subsampled data subject to different sampling strategies, covering duty cycles between 50% and 2%. The results show that a reduction of the duty cycle impacts negatively on the accuracy of both acoustic presence and call rate estimates. For a given duty cycle, frequent short listening periods improve accuracy of daily acoustic presence estimates over few long listening periods. Overall, subsampling effects are most pronounced for low and/or temporally clustered vocal activity. These findings illustrate the importance of informed decisions when applying subsampling strategies to passive acoustic recordings or analyses for a given target species. PMID:26233026

  11. Micromachined fiber optic Fabry-Perot underwater acoustic probe

    Science.gov (United States)

    Wang, Fuyin; Shao, Zhengzheng; Hu, Zhengliang; Luo, Hong; Xie, Jiehui; Hu, Yongming

    2014-08-01

    One of the most important branches in the development trend of the traditional fiber optic physical sensor is the miniaturization of sensor structure. Miniature fiber optic sensor can realize point measurement, and then to develop sensor networks to achieve quasi-distributed or distributed sensing as well as line measurement to area monitoring, which will greatly extend the application area of fiber optic sensors. The development of MEMS technology brings a light path to address the problems brought by the procedure of sensor miniaturization. Sensors manufactured by MEMS technology possess the advantages of small volume, light weight, easy fabricated and low cost. In this paper, a fiber optic extrinsic Fabry-Perot interferometric underwater acoustic probe utilizing micromachined diaphragm collaborated with fiber optic technology and MEMS technology has been designed and implemented to actualize underwater acoustic sensing. Diaphragm with central embossment, where the embossment is used to anti-hydrostatic pressure which would largely deflect the diaphragm that induce interferometric fringe fading, has been made by double-sided etching of silicon on insulator. By bonding the acoustic-sensitive diaphragm as well as a cleaved fiber end in ferrule with an outer sleeve, an extrinsic Fabry-Perot interferometer has been constructed. The sensor has been interrogated by quadrature-point control method and tested in field-stable acoustic standing wave tube. Results have been shown that the recovered signal detected by the sensor coincided well with the corresponding transmitted signal and the sensitivity response was flat in frequency range from 10 Hz to 2kHz with the value about -154.6 dB re. 1/μPa. It has been manifest that the designed sensor could be used as an underwater acoustic probe.

  12. Hybrid optical and acoustic force based sorting

    Science.gov (United States)

    O'Mahoney, Paul; Brodie, Graham W.; Wang, Han; Demore, Christine E. M.; Cochran, Sandy; Spalding, Gabriel C.; MacDonald, Michael P.

    2014-09-01

    We report the combined use of optical sorting and acoustic levitation to give particle sorting. Differing sizes of microparticles are sorted optically both with and without the aid of acoustic levitation, and the results compared to show that the use of acoustic trapping can increase sorting efficiency. The use of a transparent ultrasonic transducer is also shown to streamline the integration of optics and acoustics. We also demonstrate the balance of optical radiation pressure and acoustic levitation to achieve vertical sorting.

  13. Failure to Use Cubicles and Concentrate Dispenser by Heifers after Transfer from Rearing Accommodation to Milking Herd

    Directory of Open Access Journals (Sweden)

    Myren HJ

    2001-03-01

    Full Text Available Thirty-three dairy farms in the Norwegian counties of Østfold and Akershus in which cubicle sheds had been in use for at least one year and with a herd size of less than 60 cows, were contacted and asked to participate in a study. The study focused on heifers' use of cubicles and concentrate dispenser just after being transferred from rearing accommodation to the milking herd. For each heifer, the farmer recorded cubicle use once nightly between 9 and 11 pm. The daily amount of concentrate released in the dispenser and the allotted daily ration were also recorded. The recording period was 15 consecutive days for cubicle use and 7 days for concentrate dispenser use. Cubicle refusal behaviour, i.e. lying outside the cubicles, was analysed by logistic regression using rearing accommodation of heifers, herd size, heifer age, and housing layout as independent variables, and herd as a clustering variable. On Day 2 after transfer, 34% of the heifers were showing cubicle refusal behaviour (N = 340. By Day 15 this percentage had dropped to 23. Cubicle refusal was lower throughout the whole period among heifers which used the cubicles on the 3 first days after transfer compared to those which did not. This tendency could also be detected several months later. The analysis showed cubicle refusal to be significantly associated with rearing accommodation (OR = 6.1, c.i.95%OR = 1.5–24.3, P = 0.01 and cubicle layout in the shed (OR = 0.2, c.i.95%OR = 0.0–0.7, P = 0.01. None of the tested variables were found to be significant for failure to use the concentrate dispenser, a behaviour which was less frequent than cubicle refusal. However, 8 percent of the heifers did not visit the dispenser at all throughout the 7 days of observation.

  14. Design of a new non-sterile glove-dispensing unit to reduce touch-based contamination

    Directory of Open Access Journals (Sweden)

    Jennifer R Amos

    2014-06-01

    Full Text Available Background Despite best efforts by healthcare providers to sterilise their hands through hand washing prior to touching medical equipment and patients, bacteria are still present and can be spread through physical contact. We aimed to reduce the spread of touch-induced and airborne bacteria and virus spreading by using a touch-free glove-dispensing system that minimally exposes gloves in the box to air. Method The team met multiple times to undertake early prototyping and present ideas for the design. We experimented with folding gloves in varying patterns, similar to facial tissue-dispensing boxes, and tried several methods of opening/closing the glove box to determine the most effective way to access gloves with the least amount of physical contact. We considered the user experience and obtained user feedback after each design iteration. Results Ultimately, we decided on a vertically oriented box with optional holes for dispensing a glove on the side of the box or on the bottom by means of the pull-down drawer mechanism. This system will dispense a single glove at a time to the user with the option of using a pull-down drawer trigger to decrease the likelihood of physical contact with unused gloves. Both methods dispense a single glove. Conclusion: By reducing physical contact between the healthcare practitioner and the gloves, we are potentially reducing the spread of bacteria. This glove box design ensures that gloves are not exposed to the air in the clinic or hospital setting, thereby further reducing spread of airborne germs. This could assist in decreasing the risk of nosocomial infections in healthcare settings.

  15. Research on micro-sized acoustic bandgap structures.

    Energy Technology Data Exchange (ETDEWEB)

    Fleming, James Grant; McCormick, Frederick Bossert; Su, Mehmet F.; El-Kady, Ihab Fathy; Olsson, Roy H., III; Tuck, Melanie R.

    2010-01-01

    Phononic crystals (or acoustic crystals) are the acoustic wave analogue of photonic crystals. Here a periodic array of scattering inclusions located in a homogeneous host material forbids certain ranges of acoustic frequencies from existence within the crystal, thus creating what are known as acoustic (or phononic) bandgaps. The vast majority of phononic crystal devices reported prior to this LDRD were constructed by hand assembling scattering inclusions in a lossy viscoelastic medium, predominantly air, water or epoxy, resulting in large structures limited to frequencies below 1 MHz. Under this LDRD, phononic crystals and devices were scaled to very (VHF: 30-300 MHz) and ultra (UHF: 300-3000 MHz) high frequencies utilizing finite difference time domain (FDTD) modeling, microfabrication and micromachining technologies. This LDRD developed key breakthroughs in the areas of micro-phononic crystals including physical origins of phononic crystals, advanced FDTD modeling and design techniques, material considerations, microfabrication processes, characterization methods and device structures. Micro-phononic crystal devices realized in low-loss solid materials were emphasized in this work due to their potential applications in radio frequency communications and acoustic imaging for medical ultrasound and nondestructive testing. The results of the advanced modeling, fabrication and integrated transducer designs were that this LDRD produced the 1st measured phononic crystals and phononic crystal devices (waveguides) operating in the VHF (67 MHz) and UHF (937 MHz) frequency bands and established Sandia as a world leader in the area of micro-phononic crystals.

  16. Frequency Steered Acoustic Transducer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase II project is to fabricate, characterize, and verify performance of a new type of frequency steered acoustic...

  17. Frequency Steered Acoustic Transducer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase I project is to develop, fabricate, and characterize a novel frequency steered acoustic transducer (FSAT) for the...

  18. Reverberant Acoustic Test Facility (RATF)

    Data.gov (United States)

    Federal Laboratory Consortium — The very large Reverberant Acoustic Test Facility (RATF) at the NASA Glenn Research Center (GRC), Plum Brook Station, is currently under construction and is due to...

  19. Cryogenic Acoustic Suppression Testing Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed project will explore and test the feasibility and effectiveness of using a cryogenic fluid (liquid nitrogen) to facilitate acoustic suppression in a...

  20. Fuel Cell Technologies Office FY 2017 Budget At-A-Glance

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-03-01

    The Fuel Cell Technologies Office develops technologies to enable fuel cells to be competitive in diverse applications, with a focus on light-duty vehicles (at less than $40/kW) and to enable renewable hydrogen to be cost-competitive with gasoline (at less than $4 per gallon gasoline equivalent (gge), delivered and dispensed).

  1. NEAR-FIELD ACOUSTIC HOLOGRAPHY FOR SEMI-FREE ACOUSTIC FIELD BASED ON WAVE SUPERPOSITION APPROACH

    Institute of Scientific and Technical Information of China (English)

    LI Weibing; CHEN Jian; YU Fei; CHEN Xinzhao

    2006-01-01

    In the semi-free acoustic field, the actual acoustic pressure at any point is composed of two parts: The direct acoustic pressure and the reflected acoustic pressure. The general acoustic holographic theories and algorithms request that there is only the direct acoustic pressure contained in the pressure at any point on the hologram surface, consequently, they cannot be used to reconstruct acoustic source and predict acoustic field directly. To take the reflected pressure into consideration, near-field acoustic holography for semi-free acoustic field based on wave superposition approach is proposed to realize the holographic reconstruction and prediction of the semi-free acoustic field, and the wave superposition approach is adopted as a holographic transform algorithm. The proposed theory and algorithm are realized and verified with a numerical example,and the drawbacks of the general theories and algorithms in the holographic reconstruction and prediction of the semi-free acoustic field are also demonstrated by this numerical example.

  2. Acoustic Rectification in Dispersive Media

    Science.gov (United States)

    Cantrell, John H.

    2008-01-01

    It is shown that the shapes of acoustic radiation-induced static strain and displacement pulses (rectified acoustic pulses) are defined locally by the energy density of the generating waveform. Dispersive properties are introduced analytically by assuming that the rectified pulses are functionally dependent on a phase factor that includes both dispersive and nonlinear terms. The dispersion causes an evolutionary change in the shape of the energy density profile that leads to the generation of solitons experimentally observed in fused silica.

  3. Simplified Rotation In Acoustic Levitation

    Science.gov (United States)

    Barmatz, M. B.; Gaspar, M. S.; Trinh, E. H.

    1989-01-01

    New technique based on old discovery used to control orientation of object levitated acoustically in axisymmetric chamber. Method does not require expensive equipment like additional acoustic drivers of precisely adjustable amplitude, phase, and frequency. Reflecting object acts as second source of sound. If reflecting object large enough, close enough to levitated object, or focuses reflected sound sufficiently, Rayleigh torque exerted on levitated object by reflected sound controls orientation of object.

  4. Stable And Oscillating Acoustic Levitation

    Science.gov (United States)

    Barmatz, Martin B.; Garrett, Steven L.

    1988-01-01

    Sample stability or instability determined by levitating frequency. Degree of oscillation of acoustically levitated object along axis of levitation chamber controlled by varying frequency of acoustic driver for axis above or below frequency of corresponding chamber resonance. Stabilization/oscillation technique applied in normal Earth gravity, or in absence of gravity to bring object quickly to rest at nominal levitation position or make object oscillate in desired range about that position.

  5. Study Acoustic Emissions from Composites

    Science.gov (United States)

    Walker, James; Workman,Gary

    1998-01-01

    The purpose of this work will be to develop techniques for monitoring the acoustic emissions from carbon epoxy composite structures at cryogenic temperatures. Performance of transducers at temperatures ranging from ambient to cryogenic and the characteristics of acoustic emission from composite structures will be studied and documented. This entire effort is directed towards characterization of structures used in NASA propulsion programs such as the X-33.

  6. Opto-acoustic cell permeation

    Energy Technology Data Exchange (ETDEWEB)

    Visuri, S R; Heredia, N

    2000-03-09

    Optically generated acoustic waves have been used to temporarily permeate biological cells. This technique may be useful for enhancing transfection of DNA into cells or enhancing the absorption of locally delivered drugs. A diode-pumped frequency-doubled Nd:YAG laser operating at kHz repetition rates was used to produce a series of acoustic pulses. An acoustic wave was formed via thermoelastic expansion by depositing laser radiation into an absorbing dye. Generated pressures were measured with a PVDF hydrophone. The acoustic waves were transmitted to cultured and plated cells. The cell media contained a selection of normally- impermeable fluorescent-labeled dextran dyes. Following treatment with the opto-acoustic technique, cellular incorporation of dyes, up to 40,000 Molecular Weight, was noted. Control cells that did not receive opto-acoustic treatment had unremarkable dye incorporation. Uptake of dye was quantified via fluorescent microscopic analysis. Trypan Blue membrane exclusion assays and fluorescent labeling assays confirmed the vitality of cells following treatment. This method of enhanced drug delivery has the potential to dramatically reduce required drug dosages and associated side effects and enable revolutionary therapies.

  7. Prediction of acoustic comfort and acoustic silence in Goan Catholic churches

    OpenAIRE

    Menino A. S. M. P. Tavares; S. Rajagopalan; Satish J. Sharma; António P. O. Carvalho

    2009-01-01

    Acoustic Comfort and Acoustic Silence are determinants of tranquility in a worship space. The results presented here are part of a study that investigates the behaviour of acoustically constituted worship parameters in six Catholic churches (Goa, India). Acoustic comfort is quantified through an Acoustic Comfort Impression Index which measures the net comfort induced through the optimization of the desired subjective acoustic impressions for different types of music and different music source...

  8. Centrifugal multiplexing fixed-volume dispenser on a plastic lab-on-a-disk for parallel biochemical single-end-point assays.

    Science.gov (United States)

    La, Moonwoo; Park, Sang Min; Kim, Dong Sung

    2015-01-01

    In this study, a multiple sample dispenser for precisely metered fixed volumes was successfully designed, fabricated, and fully characterized on a plastic centrifugal lab-on-a-disk (LOD) for parallel biochemical single-end-point assays. The dispenser, namely, a centrifugal multiplexing fixed-volume dispenser (C-MUFID) was designed with microfluidic structures based on the theoretical modeling about a centrifugal circumferential filling flow. The designed LODs were fabricated with a polystyrene substrate through micromachining and they were thermally bonded with a flat substrate. Furthermore, six parallel metering and dispensing assays were conducted at the same fixed-volume (1.27 μl) with a relative variation of ±0.02 μl. Moreover, the samples were metered and dispensed at different sub-volumes. To visualize the metering and dispensing performances, the C-MUFID was integrated with a serpentine micromixer during parallel centrifugal mixing tests. Parallel biochemical single-end-point assays were successfully conducted on the developed LOD using a standard serum with albumin, glucose, and total protein reagents. The developed LOD could be widely applied to various biochemical single-end-point assays which require different volume ratios of the sample and reagent by controlling the design of the C-MUFID. The proposed LOD is feasible for point-of-care diagnostics because of its mass-producible structures, reliable metering/dispensing performance, and parallel biochemical single-end-point assays, which can identify numerous biochemical.

  9. The impact of interacting drugs on dispensed doses of warfarin in the Swedish population: A novel use of population based drug registers.

    Science.gov (United States)

    Andersson, M L; Lindh, J D; Mannheimer, B

    2013-12-01

    To investigate the impact of interacting drugs on the dispensed doses of warfarin in the Swedish population. This was a retrospective, cross-sectional population based register study of patients being dispensed warfarin. Warfarin doses were estimated in different age groups, in men and women, and in patients using interacting drugs. The influence of interacting drugs on the dispensed warfarin dose was analyzed using multiple regression. All 143,729 patients dispensed warfarin were analyzed. The dispensed dose of warfarin was highest in patients 30-39 years old and decreased with age. Co-medication with carbamazepine, simvastatin, paracetamol, amiodarone, fluconazole, lactulose, or bezafibrate was associated with significant changes in dispensed warfarin doses, by +40%, -3.4%, -7.3%, -8.2%, -8.8%, -9.0%, and -9.7%, respectively. After adjustment for age and gender, sulfamethoxazole was also found to significantly alter the dispensed warfarin dose (-6.1%). We provide new support for the previous scarce evidence of interactions between warfarin and carbamazepine, bezafibrate, and lactulose. Initiation or discontinuation of bezafibrate or lactulose in a patient on warfarin should warrant close clinical monitoring. The marked increased warfarin requirement associated with carbamazepine use supports moving from a more conservative reactive towards a proactive strategy including preventive warfarin dose adjustments to avoid potential adverse effects. PMID:24038065

  10. Estimating suspended sediment using acoustics in a fine-grained riverine system, Kickapoo Creek at Bloomington, Illinois

    Science.gov (United States)

    Manaster, Amanda D.; Domanski, Marian M.; Straub, Timothy D.; Boldt, Justin A.

    2016-08-18

    Acoustic technologies have the potential to be used as a surrogate for measuring suspended-sediment concentration (SSC). This potential was examined in a fine-grained (97-100 percent fines) riverine system in central Illinois by way of installation of an acoustic instrument. Acoustic data were collected continuously over the span of 5.5 years. Acoustic parameters were regressed against SSC data to determine the accuracy of using acoustic technology as a surrogate for measuring SSC in a fine-grained riverine system. The resulting regressions for SSC and sediment acoustic parameters had coefficients of determination ranging from 0.75 to 0.97 for various events and configurations. The overall Nash-Sutcliffe model-fit efficiency was 0.95 for the 132 observed and predicted SSC values determined using the sediment acoustic parameter regressions. The study of using acoustic technologies as a surrogate for measuring SSC in fine-grained riverine systems is ongoing. The results at this site are promising in the realm of surrogate technology.

  11. Composites Sheet Damage Acoustic Emission Localization Method Based on Optical Fiber Intensity Sensing Technology%基于强度型光纤传感技术的复合材料薄板损伤声发射定位法

    Institute of Scientific and Technical Information of China (English)

    朱永凯; 崇博; 林啸鸣; 潘仁前; 王志宏

    2011-01-01

    声发射具有对缺陷起始和扩展探测灵敏的特点,适用于复合材料薄板损伤检测,其中定位方法的研究是关键技术之一。文章结合光纤传感技术,设计并构建了声发射检测系统,实现了复合材料薄板的损伤源定位。基于三角定位原理,进行分布式光纤传感布置,在复合材料薄板上方获取损伤信号。然后将测得的信号依次利用DaubechieslO小波和Gabor小波进行背景去噪和信号峰值提取,从而获得损伤源释放的AO模态兰姆波传播到各个传感器的精确时间。最后由到达时间依据三角损伤定位算法建立非线性方程组,通过计算即可求出损伤源位置。相比其它方法,该方法具有非接触、无需测量对象材料参数的优点,在复合材料薄板损伤检测应用中有重要意义。%Acoustic emission can be applied for composites sheet damage detection because of its being sensitive to the defect's generation and expansion, and damage location is the key technology in acoustic emission. This paper provided an acoustic emission detection system combined with optical fiber sensing technology, identified the location of damage sources in composites sheets. The distributed optical fiber sensors were arranged on the top of composites sheet based on triangulation principle to detect damage signals. Then, Daubechies10 wavelet and Gabor wavelet were used to denoising and acquire signal peak to obtain the propagation time of Lamb mode(A0). Finally, the location of destructive source was obtained by computing for non-linear equations, which were established by the time of arrivals based on triangulation. This method had the advantage over other methods, such as non-contact and no use of material parameters. It was an important method to detect composites sheet damage.

  12. Acoustic Signal Processing

    Science.gov (United States)

    Hartmann, William M.; Candy, James V.

    Signal processing refers to the acquisition, storage, display, and generation of signals - also to the extraction of information from signals and the re-encoding of information. As such, signal processing in some form is an essential element in the practice of all aspects of acoustics. Signal processing algorithms enable acousticians to separate signals from noise, to perform automatic speech recognition, or to compress information for more efficient storage or transmission. Signal processing concepts are the building blocks used to construct models of speech and hearing. Now, in the 21st century, all signal processing is effectively digital signal processing. Widespread access to high-speed processing, massive memory, and inexpensive software make signal processing procedures of enormous sophistication and power available to anyone who wants to use them. Because advanced signal processing is now accessible to everybody, there is a need for primers that introduce basic mathematical concepts that underlie the digital algorithms. The present handbook chapter is intended to serve such a purpose.

  13. Acoustics of the Intonarumori

    Science.gov (United States)

    Serafin, Stefania

    2005-04-01

    The Intonarumori were a family of musical instruments invented by the Italian futurist composer and painter Luigi Russolo. Each Intonarumori was made of a wooden parallelepiped sound box, inside which a wheel of different sizes and materials was setting into vibration a catgut or metal string. The pitch of the string was varied by using a lever, while the speed of the wheel was controlled by the performer using a crank. At one end of the string there was a drumhead that transmitted vibrations to the speaker. Unfortunately, all the original Intonarumori were destroyed after a fire during World War II. Since then, researchers have tried to understand the sound production mechanism of such instruments, especially by consulting the patents compiled by Russolo or by reading his book ``The art of noise.'' In this paper we describe the acoustics of the Intonarumori. Based on such description, we propose physical models that simulate such instruments. The intonarumori's string is modeled using a one dimensional waveguide, which is excited either by an impact or a friction model. The body of the instrument is modeled using a 3-D rectangular mesh, while the horn is considered as an omnidirectional radiator.

  14. Research on Fluid Motion and Fluid Jetting Dispensing in High Performance Manufacturing of LED%高性能LED封装点胶中流体运动与胶液喷射研究

    Institute of Scientific and Technical Information of China (English)

    彭先安; 单修洋; 沈平; 李涵雄

    2014-01-01

    LED照明具有高亮度、低能耗、体积小、环保等特点,因此被认为是未来替代传统照明方式的最佳光源。而对于高粘度、高频、微量、高一致性的LED荧光粉点胶,目前还存在无法出胶、点胶性能不稳定、胶滴一致性不好等问题。首先阐述了LED照明的应用特点以及当前照明封装产业的技术水平,随后结合将来主流的喷射式点胶技术,利用Flow-3D软件建立了LED喷射点胶过程的计算机仿真模型。随后得到了点胶过程中胶液在喷胶阀内的流动情况,在此基础上又探讨了各因素对胶液喷射的影响规律。其结果可以为后续的研究奠定基础,同时对具体的LED工业生产及封装装备制造也有一定的参考价值。%LED lighting has high brightness, low power consumption, small size, environmental protection and other features, so it is considered to be the best source of future lighting method. For high viscosity, high frequency, high consistency of the LED phosphor dispensing, there are still some problems.Such as can’t jet glue, glue performance is not stable, dots consistency is not good and so on.The paper first describes the characteristics of LED lighting and the lighting package industry technical level, and then combined with the future mainstream jet dispensing technology, establish a computer simulation model of the LED jet dispensing process by using Flow-3D software. Then obtain the flow situation of glue dispensing process in the spray valve, and on the basis of it, discuss the factors to the glue injection. The results can lay a foundation for related research, also has certain reference function to the concrete LED industrial production and packaging equipment manufacturing.

  15. Characterization of Alkali Metal Dispensers and Non-Evaporable Getter Pumps in Ultra-High Vacuum Systems for Cold Atomic Sensors

    OpenAIRE

    Scherer, David R.; Fenner, David B.; Hensley, Joel M.

    2012-01-01

    A glass ultrahigh vacuum chamber with rubidium alkali metal dispensers and non-evaporable getter pumps has been developed and used to create a cold atomic sample in a chamber that operates with only passive vacuum pumps. The ion-mass spectrum of evaporated gases from the alkali metal dispenser has been recorded as a function of dispenser current. The efficacy of the non-evaporable getter pumps in promoting and maintaining vacuum has been characterized by observation of the Rb vapor optical ab...

  16. Experimental Study on Bridge Monitoring Based on Optical Fiber Acoustic Emission Sensing Technology%基于光纤声发射传感技术的桥梁监测实验研究

    Institute of Scientific and Technical Information of China (English)

    单宁

    2011-01-01

    The optical fiber sensor can meet the requirements of the real-time health monitoring of the bridge structure with its features of good wearing, small size and easy to realize the distribution detection. A extrinsic optical fiber F-P sensor structure has been designed in this work and the sensing mechanism of the optical fiber F-P acoustic emission has been analyzed. A detection system based on the optical fiber F-P acoustic emission technolgy has been fabricated for detecting the health state of the concrete bridge on-line in real time. The experimemtal results showed that the sesor has the features of simple structure, small size, cost-effectiveness and easy-to-fabricate. It can be used for the bridge health detection effectively and is easy to produce commercially.%光纤传感器耐久性好,体积小,质量轻,易于实现分布式检测,能满足桥梁等土木结构的实时健康监测.该文设计了一非本征光纤法布里-珀罗(F-P)传感器结构,分析了光纤F-P声发射传感机理,建立了基于光纤F-P声发射传感技术的检测系统,用于混凝土桥梁健康状况的实时在线检测.实验结果表明,该传感器结构简单,体积小,成本低,制作容易,能有效用于桥梁健康监测,易于实现商品化.

  17. Focusing of Acoustic Waves through Acoustic Materials with Subwavelength Structures

    KAUST Repository

    Xiao, Bingmu

    2013-05-01

    In this thesis, wave propagation through acoustic materials with subwavelength slits structures is studied. Guided by the findings, acoustic wave focusing is achieved with a specific material design. By using a parameter retrieving method, an effective medium theory for a slab with periodic subwavelength cut-through slits is successfully derived. The theory is based on eigenfunction solutions to the acoustic wave equation. Numerical simulations are implemented by the finite-difference time-domain (FDTD) method for the two-dimensional acoustic wave equation. The theory provides the effective impedance and refractive index functions for the equivalent medium, which can reproduce the transmission and reflection spectral responses of the original structure. I analytically and numerically investigate both the validity and limitations of the theory, and the influences of material and geometry on the effective spectral responses are studied. Results show that large contrasts in impedance and density are conditions that validate the effective medium theory, and this approximation displays a better accuracy for a thick slab with narrow slits in it. Based on the effective medium theory developed, a design of a at slab with a snake shaped" subwavelength structure is proposed as a means of achieving acoustic focusing. The property of focusing is demonstrated by FDTD simulations. Good agreement is observed between the proposed structure and the equivalent lens pre- dicted by the theory, which leads to robust broadband focusing by a thin at slab.

  18. Acoustic communication in plant-animal interactions.

    Science.gov (United States)

    Schöner, Michael G; Simon, Ralph; Schöner, Caroline R

    2016-08-01

    Acoustic communication is widespread and well-studied in animals but has been neglected in other organisms such as plants. However, there is growing evidence for acoustic communication in plant-animal interactions. While knowledge about active acoustic signalling in plants (i.e. active sound production) is still in its infancy, research on passive acoustic signalling (i.e. reflection of animal sounds) revealed that bat-dependent plants have adapted to the bats' echolocation systems by providing acoustic reflectors to attract their animal partners. Understanding the proximate mechanisms and ultimate causes of acoustic communication will shed light on an underestimated dimension of information transfer between plants and animals. PMID:27423052

  19. Modelling of acoustic transmission through perforated layer

    Directory of Open Access Journals (Sweden)

    Lukeš V.

    2007-10-01

    Full Text Available The paper deals with modeling the acoustic transmission through a perforated interface plane separating two halfspaces occupied by the acoustic medium. We considered the two-scale homogenization limit of the standard acoustic problem imposed in the layer with the perforated periodic structure embedded inside. The homogenized transmission conditions govern the interface discontinuity of the acoustic pressure associated with the two halfspaces and the magnitude of the fictitious transversal acoustic velocity. By numerical examples we illustrate this novel approach of modeling the acoustic impedance of perforated interfaces.

  20. Combining Passive Thermography and Acoustic Emission for Large Area Fatigue Damage Growth Assessment of a Composite Structure

    Science.gov (United States)

    Zalameda, Joseph N.; Horne, Michael R.; Madaras, Eric I.; Burke, Eric R.

    2016-01-01

    Passive thermography and acoustic emission data were obtained for improved real time damage detection during fatigue loading. A strong positive correlation was demonstrated between acoustic energy event location and thermal heating, especially if the structure under load was nearing ultimate failure. An image processing routine was developed to map the acoustic emission data onto the thermal imagery. This required removing optical barrel distortion and angular rotation from the thermal data. The acoustic emission data were then mapped onto thermal data, revealing the cluster of acoustic emission event locations around the thermal signatures of interest. By combining both techniques, progression of damage growth is confirmed and areas of failure are identified. This technology provides improved real time inspections of advanced composite structures during fatigue testing.Keywords: Thermal nondestructive evaluation, fatigue damage detection, aerospace composite inspection, acoustic emission, passive thermography

  1. Underwater hybrid near-field acoustical holography based on the measurement of vector hydrophone array

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Hybrid near-field acoustical holography(NAH) is developed for reconstructing acoustic radiation from a cylindrical source in a complex underwater environment. In hybrid NAH,we combine statistically optimized near-field acoustical holography(SONAH) and broadband acoustical holography from intensity measurements(BAHIM) to reconstruct the underwater cylindrical source field. First,the BAHIM is utilized to regenerate as much acoustic pressures on the hologram surface as necessary,and then the acoustic pressures are taken as input to the formulation implemented numerically by SONAH. The main advantages of this technology are that the complex pressure on the hologram surface can be reconstructed without reference signal,and the measurement array can be smaller than the source,thus the practicability and efficiency of this technology are greatly enhanced. Numerical examples of a cylindrical source are demonstrated. Test results show that hybrid NAH can yield a more accurate reconstruction than conventional NAH. Then,an experiment has been carried out with a vector hydrophone array. The experimental results show the advantage of hybrid NAH in the reconstruction of an acoustic field and the feasibility of using a vector hydrophone array in an underwater NAH measurement,as well as the identification and localization of noise sources.

  2. Three-dimensional manipulation of single cells using surface acoustic waves

    OpenAIRE

    Guo, Feng; Mao, Zhangming; Chen, Yuchao; Xie, Zhiwei; James P Lata; Li, Peng; Ren, Liqiang; Liu, Jiayang; Yang, Jian; Dao, Ming; Suresh, Subra; Huang, Tony Jun

    2016-01-01

    We present 3D acoustic tweezers, which can trap and manipulate single cells and particles along three mutually orthogonal axes of motion by recourse to surface acoustic waves. We use 3D acoustic tweezers to pick up single cells, or entire cell assemblies, and deliver them to desired locations to create 2D and 3D cell patterns, or print the cells into complex shapes. This technology is thus shown to offer better performance over prior cell manipulation techniques in terms of both accurate and ...

  3. Sonification of acoustic emission data

    Science.gov (United States)

    Raith, Manuel; Große, Christian

    2014-05-01

    While loading different specimens, acoustic emissions appear due to micro crack formation or friction of already existing crack edges. These acoustic emissions can be recorded using suitable ultrasonic transducers and transient recorders. The analysis of acoustic emissions can be used to investigate the mechanical behavior of different specimens under load. Our working group has undertaken several experiments, monitored with acoustic emission techniques. Different materials such as natural stone, concrete, wood, steel, carbon composites and bone were investigated. Also the experimental setup has been varied. Fire-spalling experiments on ultrahigh performance concrete and pullout experiments on bonded anchors have been carried out. Furthermore uniaxial compression tests on natural stone and animal bone had been conducted. The analysis tools include not only the counting of events but the analysis of full waveforms. Powerful localization algorithms and automatic onset picking techniques (based on Akaikes Information Criterion) were established to handle the huge amount of data. Up to several thousand events were recorded during experiments of a few minutes. More sophisticated techniques like moment tensor inversion have been established on this relatively small scale as well. Problems are related to the amount of data but also to signal-to-noise quality, boundary conditions (reflections) sensor characteristics and unknown and changing Greens functions of the media. Some of the acoustic emissions recorded during these experiments had been transferred into audio range. The transformation into the audio range was done using Matlab. It is the aim of the sonification to establish a tool that is on one hand able to help controlling the experiment in-situ and probably adjust the load parameters according to the number and intensity of the acoustic emissions. On the other hand sonification can help to improve the understanding of acoustic emission techniques for training

  4. Acoustic constituents of prosodic typology

    Science.gov (United States)

    Komatsu, Masahiko

    Different languages sound different, and considerable part of it derives from the typological difference of prosody. Although such difference is often referred to as lexical accent types (stress accent, pitch accent, and tone; e.g. English, Japanese, and Chinese respectively) and rhythm types (stress-, syllable-, and mora-timed rhythms; e.g. English, Spanish, and Japanese respectively), it is unclear whether these types are determined in terms of acoustic properties, The thesis intends to provide a potential basis for the description of prosody in terms of acoustics. It argues for the hypothesis that the source component of the source-filter model (acoustic features) approximately corresponds to prosody (linguistic features) through several experimental-phonetic studies. The study consists of four parts. (1) Preliminary experiment: Perceptual language identification tests were performed using English and Japanese speech samples whose frequency spectral information (i.e. non-source component) is heavily reduced. The results indicated that humans can discriminate languages with such signals. (2) Discussion on the linguistic information that the source component contains: This part constitutes the foundation of the argument of the thesis. Perception tests of consonants with the source signal indicated that the source component carries the information on broad categories of phonemes that contributes to the creation of rhythm. (3) Acoustic analysis: The speech samples of Chinese, English, Japanese, and Spanish, differing in prosodic types, were analyzed. These languages showed difference in acoustic characteristics of the source component. (4) Perceptual experiment: A language identification test for the above four languages was performed using the source signal with its acoustic features parameterized. It revealed that humans can discriminate prosodic types solely with the source features and that the discrimination is easier as acoustic information increases. The

  5. CALCULATION OF ACOUSTIC EFFICIENCY OF PORTABLE ACOUSTIC SCREEN

    Directory of Open Access Journals (Sweden)

    Aleksandr Skvortsov

    2016-03-01

    Full Text Available The research of influence of life environment adverse factors on physical development and health of population is an actual problem of ecology. The aspects of the most actual problems of the modern world, namely environmental industrial noise pollution are considered in the article. Industrial facilities everywhere have noisy equipment. Noise is a significant factors of negative influenceon people and environment. Combined effects of noise and of other physical pollutions on people may cause amplification of their negative impact. If the noise pollution level from the object in a residential area exceeds the permissible levels (MPL, noise protection measures can be initiated. Today, the most common design decisions for noise protection are sound absorbing construction, noise screens and barriers, acousting housings, soundproff cabins. Many of them are popular, others are less known. The article deals with one of the most wide spread means of noise protection – a portable acoustic screen. The aim of the research is to determine the efficiency of portable acoustic screens. It is shown that the installation of such structures can reduce the average value of the sound level. The authors analyzed acoustic screens as device to reduce noise pollution. The authors offer a potable acoustic screen differing from the used easyness, mobility, minimum price and good sound protective properties. Effectiveness, a sound absorption coefficient and sound conductivity coefficient of a portable acoustic screen are evaluated. The descriptions of the algorithm calculations and the combination of technical solutions have practical originality. The results of the research demonstrate the advantages of the proposed solutions for reducing noise levels in the agro-industrial complex.

  6. Passive acoustic threat detection in estuarine environments

    Science.gov (United States)

    Borowski, Brian; Sutin, Alexander; Roh, Heui-Seol; Bunin, Barry

    2008-04-01

    The Maritime Security Laboratory (MSL) at Stevens Institute of Technology supports research in a range of areas relevant to harbor security, including passive acoustic detection of underwater threats. The difficulties in using passive detection in an urban estuarine environment include intensive and highly irregular ambient noise and the complexity of sound propagation in shallow water. MSL conducted a set of tests in the Hudson River near Manhattan in order to measure the main parameters defining the detection distance of a threat: source level of a scuba diver, transmission loss of acoustic signals, and ambient noise. The source level of the diver was measured by comparing the diver's sound with a reference signal from a calibrated emitter placed on his path. Transmission loss was measured by comparing noise levels of passing ships at various points along their routes, where their distance from the hydrophone was calculated with the help of cameras and custom software. The ambient noise in the Hudson River was recorded under varying environmental conditions and amounts of water traffic. The passive sonar equation was then applied to estimate the range of detection. Estimations were done for a subset of the recorded noise levels, and we demonstrated how variations in the noise level, attenuation, and the diver's source level influence the effective range of detection. Finally, we provided analytic estimates of how an array improves upon the detection distance calculated by a single hydrophone.

  7. Characterization of Acoustic Droplet Vaporization Using MRI

    Science.gov (United States)

    Li, David; Allen, Steven; Hernandez-Garcia, Luis; Bull, Joseph

    2013-11-01

    Acoustic droplet vaporization (ADV) is the selective vaporization of liquid droplets to form larger gas bubbles. The ADV process is currently being researched for biomedical applications such as gas embolotherapy, drug delivery, and phase-change contrast agents. In this study an albumin encapsulated dodecafluoropentane (DDFP, CAS: 678-26-2) microdroplet suspension was vaporized using a single element focused (f/2, D = 19 mm) 3.5 MHz transducer (Panametrics A321S, Olympus, Waltham, MA). The resulting DDFP bubble clouds were imaged using both bright field microscopy and MRI (Varian 7T, Agilent Technologies Inc., Santa Clara, CA). Field distortions due to DDFP bubble generation were characterized against the bright field images as a function of acoustic power and bubble cloud size. Experimentally a direct correlation between bubble cloud dimensions generated and field distortions seen in the MRI was observed. Additionally, MR velocimetry was used to measure the flow field resulting from ADV. The field distortions due to the bubbles were further characterized by modeling Maxwell's equations using COMSOL (COMSOL Inc., Burlington, MA). The ability to characterize ADV with alternative imaging modalities may prove useful in further development of ADV based biomedical therapies.

  8. My 65 years in acoustics

    Science.gov (United States)

    Beranek, Leo L.

    2001-05-01

    My entry into acoustics began as research assistant to Professor F. V. Hunt at Harvard University. I received my doctorate in 1940 and directed the Electro-Acoustic Laboratory at Harvard from October 1940 until September 1945. In 1947, I became a tenured associate professor at MIT, and, with Richard H. Bolt, formed the consulting firm Bolt and Beranek, that later included Robert B. Newman, becoming BBN. My most significant contributions before 1970 were design of wedge-lined anechoic chambers, systemization of noise reduction in ventilation systems, design of the world's largest muffler for the testing of supersonic jet engines at NASA's Lewis Laboratory in Cleveland, speech interference level, NC noise criterion curves, heading New York Port Authority's noise study that resulted in mufflers on jet aircraft, and steep aircraft climb procedures, and publishing books titled, Acoustical Measurements, Acoustics, Noise Reduction, Noise and Vibration Control, and Music, Acoustics and Architecture. As President of BBN, I supervised the formation of the group that built and operated the ARPANET (1969), which, when split in two (using TCP/IP protocol) became the INTERNET (1984). Since then, I have written two books on Concert Halls and Opera Houses and have consulted on four concert halls and an opera house.

  9. Acoustic diagnosis of mechanical fault feature based on reference signal frequency domain semi-blind extraction

    OpenAIRE

    Zeguang YI; Pan, Nan; Liu, Feng

    2015-01-01

    Aiming at fault diagnosis problems caused by complex machinery parts, serious background noises and the application limitations of traditional blind signal processing algorithm to the mechanical acoustic signal processing, a failure acoustic diagnosis based on reference signal frequency domain semi-blind extraction is proposed. Key technologies are introduced: Based on frequency-domain blind deconvolution algorithm, the artificial fish swarm algorithm which is good for global optimization is ...

  10. Investigation of Thermal Acoustic Effects on SRF Cavities within CM1 at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    McGee, Mike [Fermilab; Harms, Elvin [Fermilab; Klebaner, Arkadiy [Fermilab; Leibfritz, Jerry [Fermilab; Martinez, Alex [Fermilab; Pischalnikov, Yuriy [Fermilab; Schappert, Warren [Fermilab

    2016-06-01

    Two TESLA-style 8-cavity cryomodules have been operated at Fermilab Accelerator Science and Technology (FAST), formerly the Superconducting Radio Frequency (SRF) Accelerator Test Facility. Operational instabilities were revealed during Radio Frequency (RF) power studies. These observations were complemented by the characterization of thermal acoustic effects on cavity microphonics manifested by apparent noisy boiling of helium involving vapor bubble and liquid vibration. The thermal acoustic measurements also consider pressure and temperature spikes which drive the phenomenon at low and high frequencies.

  11. Baleen whale acoustic ecology with focus on minke whales (Balaenoptera acutorostrata) and reference to anthropogenic noise

    OpenAIRE

    Risch, Denise

    2013-01-01

    Passive acoustic approaches for studying marine mammals have developed substantially over the past decade. Advances in technology now allow data collection in remote areas and over extended timescales. The first two chapters of this thesis focused on the application of passive acoustics for monitoring migratory baleen whales in the Northwest Atlantic Ocean. The development and application of new localization algorithms showed how small-scale arrays can be used to obtain base...

  12. Making the case for change: What researchers need to consider when designing behavior change interventions aimed at improving medication dispensing.

    Science.gov (United States)

    Cadogan, Cathal A; Ryan, Cristín; Hughes, Carmel

    2016-01-01

    There is a growing emphasis on behavior change in intervention development programmes aimed at improving public health and healthcare professionals' practice. A number of frameworks and methodological tools have been established to assist researchers in developing interventions seeking to change healthcare professionals' behaviors. The key features of behavior change intervention design involve specifying the target group (i.e. healthcare professional or patient cohort), the target behavior and identifying mediators (i.e. barriers and facilitators) of behavior change. Once the target behavior is clearly specified and understood, specific behavior change techniques can then be used as the basis of the intervention to target identified mediators of behavior change. This commentary outlines the challenges for pharmacy practice-based researchers in targeting dispensing as a behavior when developing behavior change interventions aimed at pharmacists and proposes a definition of dispensing to consider in future research. PMID:25936272

  13. Extension of the commercial agreement on water dispensers: appendices 1-4; Erweiterung der Branchenvereinbarung Wasserdispenser. Anhaenge 1-4

    Energy Technology Data Exchange (ETDEWEB)

    Grieder, T.; Huser, A.

    2006-07-01

    These appendices to a final report for the Swiss Federal Office of Energy (SFOE) present the results of work done within the framework of a voluntary agreement between the Federal Office of Energy and the four most important suppliers of bottled water dispensers in Switzerland. The first appendix lists water dispensers with water-mains connections and quotes figures on the number of units and their energy use. Two prognoses are presented for the year 2015, one with and one without any action being taken. The second appendix presents the German Gas and Water association's suggestion for standards, while the third appendix presents the hygiene regulations of the Swiss Department of Home Affairs. The fourth appendix presents the answer sent by the U.S.A's Environmental Protection Agency to an e-mail on the subject.

  14. 英国养老院发药纪实与体会%Experience of dispensing in nursing home in England

    Institute of Scientific and Technical Information of China (English)

    廉旭蓉

    2011-01-01

    文章叙述了英国养老院发药的实际情况,从发药的准备、实施和药品管理等各个环节,以严密而切合实际的操作要求和质量控制,确保护理人员发药准确到位,把以患者为中心真正落到实处,并强化以人为本的管理理念.%This paper introduced the real situation of dispensing in nursing home in England, including preparation, implementation, drug management, and so on. The whole system had strict and practical implementation rules and quality control to ensure accurate dispensing. It was patient - centered in truth and strengthened people - oriented management philosophy.

  15. Acoustic metasurface with hybrid resonances.

    Science.gov (United States)

    Ma, Guancong; Yang, Min; Xiao, Songwen; Yang, Zhiyu; Sheng, Ping

    2014-09-01

    An impedance-matched surface has the property that an incident wave generates no reflection. Here we demonstrate that by using a simple construction, an acoustically reflecting surface can acquire hybrid resonances and becomes impedance-matched to airborne sound at tunable frequencies, such that no reflection is generated. Each resonant cell of the metasurface is deep-subwavelength in all its spatial dimensions, with its thickness less than the peak absorption wavelength by two orders of magnitude. As there can be no transmission, the impedance-matched acoustic wave is hence either completely absorbed at one or multiple frequencies, or converted into other form(s) of energy, such as an electrical current. A high acoustic-electrical energy conversion efficiency of 23% is achieved. PMID:24880731

  16. Acoustic Localization with Infrasonic Signals

    Science.gov (United States)

    Threatt, Arnesha; Elbing, Brian

    2015-11-01

    Numerous geophysical and anthropogenic events emit infrasonic frequencies (wind turbines and tornadoes. These sounds, which cannot be heard by the human ear, can be detected from large distances (in excess of 100 miles) due to low frequency acoustic signals having a very low decay rate in the atmosphere. Thus infrasound could be used for long-range, passive monitoring and detection of these events. An array of microphones separated by known distances can be used to locate a given source, which is known as acoustic localization. However, acoustic localization with infrasound is particularly challenging due to contamination from other signals, sensitivity to wind noise and producing a trusted source for system development. The objective of the current work is to create an infrasonic source using a propane torch wand or a subwoofer and locate the source using multiple infrasonic microphones. This presentation will present preliminary results from various microphone configurations used to locate the source.

  17. Acoustic Communication for Medical Nanorobots

    CERN Document Server

    Hogg, Tad

    2012-01-01

    Communication among microscopic robots (nanorobots) can coordinate their activities for biomedical tasks. The feasibility of in vivo ultrasonic communication is evaluated for micron-size robots broadcasting into various types of tissues. Frequencies between 10MHz and 300MHz give the best tradeoff between efficient acoustic generation and attenuation for communication over distances of about 100 microns. Based on these results, we find power available from ambient oxygen and glucose in the bloodstream can readily support communication rates up to 10,000 bits/second between micron-sized robots. We discuss techniques, such as directional acoustic beams, that can increase this rate. The acoustic pressure fields enabling this communication are unlikely to damage nearby tissue, and short bursts at considerably higher power could be of therapeutic use.

  18. Ethanol distribution, dispensing, and use: analysis of a portion of the biomass-to-biofuels supply chain using system dynamics.

    Directory of Open Access Journals (Sweden)

    Laura J Vimmerstedt

    Full Text Available The Energy Independence and Security Act of 2007 targets use of 36 billion gallons of biofuels per year by 2022. Achieving this may require substantial changes to current transportation fuel systems for distribution, dispensing, and use in vehicles. The U.S. Department of Energy and the National Renewable Energy Laboratory designed a system dynamics approach to help focus government action by determining what supply chain changes would have the greatest potential to accelerate biofuels deployment. The National Renewable Energy Laboratory developed the Biomass Scenario Model, a system dynamics model which represents the primary system effects and dependencies in the biomass-to-biofuels supply chain. The model provides a framework for developing scenarios and conducting biofuels policy analysis. This paper focuses on the downstream portion of the supply chain-represented in the distribution logistics, dispensing station, and fuel utilization, and vehicle modules of the Biomass Scenario Model. This model initially focused on ethanol, but has since been expanded to include other biofuels. Some portions of this system are represented dynamically with major interactions and feedbacks, especially those related to a dispensing station owner's decision whether to offer ethanol fuel and a consumer's choice whether to purchase that fuel. Other portions of the system are modeled with little or no dynamics; the vehicle choices of consumers are represented as discrete scenarios. This paper explores conditions needed to sustain an ethanol fuel market and identifies implications of these findings for program and policy goals. A large, economically sustainable ethanol fuel market (or other biofuel market requires low end-user fuel price relative to gasoline and sufficient producer payment, which are difficult to achieve simultaneously. Other requirements (different for ethanol vs. other biofuel markets include the need for infrastructure for distribution and

  19. Design of a new non-sterile glove-dispensing unit to reduce touch-based contamination

    OpenAIRE

    Amos, Jennifer R; Moy, Ashley S; Audrey Gomez

    2014-01-01

    Background Despite best efforts by healthcare providers to sterilise their hands through hand washing prior to touching medical equipment and patients, bacteria are still present and can be spread through physical contact. We aimed to reduce the spread of touch-induced and airborne bacteria and virus spreading by using a touch-free glove-dispensing system that minimally exposes gloves in the box to air. Method The team met multiple times to undertake early p...

  20. Policy implementation and financial incentives for nurses in South Africa: a case study on the occupation specific dispensation

    OpenAIRE

    Ditlopo, Prudence; Blaauw, Duane; Rispel, Laetitia C.; Thomas, Steve; Bidwell, Posy

    2013-01-01

    Background: In 2007, the South African government introduced the occupation-specific dispensation (OSD), a financial incentive strategy, to attract, motivate, and retain health professionals in the public sector. Implementation commenced with the nursing sector, but there have been unintended negative consequences.Objective: First, to examine implementation of the OSD for nurses using Hogwood and Gunn’s framework that outlines ‘perfect implementation’ pre-conditions. Second, to highlight the ...

  1. Policy implementation and financial incentives for nurses in South Africa: a case study on the occupation specific dispensation

    OpenAIRE

    Thomas, Stephen

    2013-01-01

    Background: In 2007, the South African government introduced the occupation-specific dispensation (OSD), a financial incentive strategy, to attract, motivate, and retain health professionals in the public sector. Implementation commenced with the nursing sector, but there have been unintended negative consequences. Objective: First, to examine implementation of the OSD for nurses using Hogwood and Gunn's framework that outlines 'perfect implementation' pre-conditions. Second, to highlight...

  2. Knowledge and conduct of pharmacists for dispensing of drugs in community pharmacies: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Tiago Marques dos Reis

    2015-09-01

    Full Text Available The objective of the study was to evaluate the knowledge of pharmacists and check their conduct in relation to dispensing of drugs. This is a cross-sectional study performed in four municipalities from South and Southeast of Brazil, which are reference in health national scenario and concentrate 73.6% of national economic activity. Pharmacists who works in community pharmacies were invited to answer a questionnaire prepared by the authors of this study and validated. The main outcome measured was the pharmaceutical knowledge, rated according to the number of correct answers on that questionnaire prepared by the researchers, and professional conduct in relation to dispensing of drugs. The data collection occurred from September to December 2012 and the information obtained were tabulated in duplicate by two independent researchers for later analysis. 486 community pharmacies were visited but only 112 professionals participated in the study. Among the participants, 78.6% (n = 88 did not have adequate knowledge to perform the dispensing of drugs, despite this same number of pharmacists claiming to have participated in conferences and courses after graduation. The main sources of information on drugs used by participants have a low level of scientific evidence. The performance of non-employment related tasks reduces the time available for the care of medication users. In addition, the indiscriminate sale of antimicrobials and the sale of products other than health, mischaracterize the role of the pharmacist in the community pharmacy. There are gaps in the knowledge of professionals, limiting the satisfactory completion of dispensing of drugs. In addition, the excess of other duties and inadequate professional conduct compromise the promotion of the rational use of drugs.

  3. Ethanol distribution, dispensing, and use: analysis of a portion of the biomass-to-biofuels supply chain using system dynamics.

    Science.gov (United States)

    Vimmerstedt, Laura J; Bush, Brian; Peterson, Steve

    2012-01-01

    The Energy Independence and Security Act of 2007 targets use of 36 billion gallons of biofuels per year by 2022. Achieving this may require substantial changes to current transportation fuel systems for distribution, dispensing, and use in vehicles. The U.S. Department of Energy and the National Renewable Energy Laboratory designed a system dynamics approach to help focus government action by determining what supply chain changes would have the greatest potential to accelerate biofuels deployment. The National Renewable Energy Laboratory developed the Biomass Scenario Model, a system dynamics model which represents the primary system effects and dependencies in the biomass-to-biofuels supply chain. The model provides a framework for developing scenarios and conducting biofuels policy analysis. This paper focuses on the downstream portion of the supply chain-represented in the distribution logistics, dispensing station, and fuel utilization, and vehicle modules of the Biomass Scenario Model. This model initially focused on ethanol, but has since been expanded to include other biofuels. Some portions of this system are represented dynamically with major interactions and feedbacks, especially those related to a dispensing station owner's decision whether to offer ethanol fuel and a consumer's choice whether to purchase that fuel. Other portions of the system are modeled with little or no dynamics; the vehicle choices of consumers are represented as discrete scenarios. This paper explores conditions needed to sustain an ethanol fuel market and identifies implications of these findings for program and policy goals. A large, economically sustainable ethanol fuel market (or other biofuel market) requires low end-user fuel price relative to gasoline and sufficient producer payment, which are difficult to achieve simultaneously. Other requirements (different for ethanol vs. other biofuel markets) include the need for infrastructure for distribution and dispensing and

  4. Ethanol distribution, dispensing, and use: analysis of a portion of the biomass-to-biofuels supply chain using system dynamics.

    Science.gov (United States)

    Vimmerstedt, Laura J; Bush, Brian; Peterson, Steve

    2012-01-01

    The Energy Independence and Security Act of 2007 targets use of 36 billion gallons of biofuels per year by 2022. Achieving this may require substantial changes to current transportation fuel systems for distribution, dispensing, and use in vehicles. The U.S. Department of Energy and the National Renewable Energy Laboratory designed a system dynamics approach to help focus government action by determining what supply chain changes would have the greatest potential to accelerate biofuels deployment. The National Renewable Energy Laboratory developed the Biomass Scenario Model, a system dynamics model which represents the primary system effects and dependencies in the biomass-to-biofuels supply chain. The model provides a framework for developing scenarios and conducting biofuels policy analysis. This paper focuses on the downstream portion of the supply chain-represented in the distribution logistics, dispensing station, and fuel utilization, and vehicle modules of the Biomass Scenario Model. This model initially focused on ethanol, but has since been expanded to include other biofuels. Some portions of this system are represented dynamically with major interactions and feedbacks, especially those related to a dispensing station owner's decision whether to offer ethanol fuel and a consumer's choice whether to purchase that fuel. Other portions of the system are modeled with little or no dynamics; the vehicle choices of consumers are represented as discrete scenarios. This paper explores conditions needed to sustain an ethanol fuel market and identifies implications of these findings for program and policy goals. A large, economically sustainable ethanol fuel market (or other biofuel market) requires low end-user fuel price relative to gasoline and sufficient producer payment, which are difficult to achieve simultaneously. Other requirements (different for ethanol vs. other biofuel markets) include the need for infrastructure for distribution and dispensing and

  5. On Architectural Acoustics Design using Computer Simulation

    DEFF Research Database (Denmark)

    Schmidt, Anne Marie Due; Kirkegaard, Poul Henning

    2004-01-01

    The acoustical quality of a given building, or space within the building, is highly dependent on the architectural design. Architectural acoustics design has in the past been based on simple design rules. However, with a growing complexity in the architectural acoustic and the emergence of potent...... room acoustic simulation programs it is now possible to subjectively analyze and evaluate acoustic properties prior to the actual construction of a facility. With the right tools applied, the acoustic design can become an integrated part of the architectural design process. The aim of the present paper...... is to investigate the field of application an acoustic simulation program can have during an architectural acoustics design process. A case study is carried out in order to represent the iterative working process of an architect. The working process is divided into five phases and represented by typical results...

  6. Acoustojet: acoustic analogue of photonic jet phenomenon

    CERN Document Server

    Minin, Igor V

    2016-01-01

    It has been demonstrated for the first time that an existence of acoustic analogue of photonic jet phenomenon, called acoustojet, providing for subwavelength localization of acoustic field in the shadow area of arbitrary 3D penetrable mesoscale particle, is possible.

  7. Golden Gate and Pt. Reyes Acoustic Detections

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains detections of acoustic tagged fish from two general locations: Golden Gate (east and west line) and Pt. Reyes. Several Vemco 69khz acoustic...

  8. Vestibular Schwannoma (Acoustic Neuroma) and Neurofibromatosis

    Science.gov (United States)

    ... Home » Health Info » Hearing, Ear Infections, and Deafness Vestibular Schwannoma (Acoustic Neuroma) and Neurofibromatosis On this page: ... more information about vestibular schwannomas? What is a vestibular schwannoma (acoustic neuroma)? Inner ear with vestibular schwannoma ( ...

  9. On the Synchronization of Acoustic Gravity Waves

    Science.gov (United States)

    Lonngren, Karl E.; Bai, Er-Wei

    Using the model proposed by Stenflo, we demonstrate that acoustic gravity waves found in one region of space can be synchronized with acoustic gravity waves found in another region of space using techniques from modern control theory.

  10. Acoustic network event classification using swarm optimization

    Science.gov (United States)

    Burman, Jerry

    2013-05-01

    Classifying acoustic signals detected by distributed sensor networks is a difficult problem due to the wide variations that can occur in the transmission of terrestrial, subterranean, seismic and aerial events. An acoustic event classifier was developed that uses particle swarm optimization to perform a flexible time correlation of a sensed acoustic signature to reference data. In order to mitigate the effects from interference such as multipath, the classifier fuses signatures from multiple sensors to form a composite sensed acoustic signature and then automatically matches the composite signature with reference data. The approach can classify all types of acoustic events but is particularly well suited to explosive events such as gun shots, mortar blasts and improvised explosive devices that produce an acoustic signature having a shock wave component that is aperiodic and non-linear. The classifier was applied to field data and yielded excellent results in terms of reconstructing degraded acoustic signatures from multiple sensors and in classifying disparate acoustic events.

  11. Nmnat3 Is Dispensable in Mitochondrial NAD Level Maintenance In Vivo.

    Directory of Open Access Journals (Sweden)

    Masashi Yamamoto

    Full Text Available Nicotinamide adenine dinucleotide (NAD is an essential co-enzyme mediating various enzymatic reactions. Mitochondrial NAD particularly occupies a considerable amount of total NAD in cells, and serves as a co-enzyme in tricarboxylic acid cycle (TCA cycle, β-oxidation, and oxidative phosphorylation. Despite the importance of mitochondrial NAD, its synthesis pathway remains unknown. It has been proposed that NAD synthesis enzyme, Nmnat3, was localized in mitochondria, but its physiological relevance to the metabolism in mitochondria was not fully elucidated. Previously, we have reported that murine Nmnat3 protein was strongly expressed in the cytoplasm of mature erythrocytes, in which mitochondria were absent, and Nmnat3-deficient mice (Nmnat3-KO mice exhibited splenomegaly and hemolytic anemia due to reduced NAD levels in mature erythrocytes. These results challenged the role of Nmnat3 in mitochondrial NAD synthesis. In this study, we demonstrated that mitochondrial NAD levels in various tissues, except for red blood cells, were unchanged in Nmnat3-KO mice. We also analyzed the metabolites in glycolysis and TCA cycle and found that there were no differences between Nmnat3-KO and WT mice. In addition, the aged Nmnat3-KO mice had comparable NAD levels to that observed in WT mice. Our results indicated that Nmnat3 is dispensable in the maintenance of mitochondrial NAD levels, and that other NAD regulatory pathways may exist in mitochondria.

  12. Productive performance of Nile tilapia (Oreochromis niloticus fed at different frequencies and periods with automatic dispenser

    Directory of Open Access Journals (Sweden)

    R.M.R. Sousa

    2012-02-01

    Full Text Available The performance of Nile tilapia (Oreochromis niloticus raised in cages furnished with an automatic dispenser, supplied at different frequencies (once per hour and once every two hours and periods (daytime, nighttime and both was evaluated. Eighteen 1.0m³ cages were placed into a 2000m² pond, two meters deep with a 5% water exchange. One hundred and seventy tilapias, with initial weight of 16.0±4.9g, were dispersed into each 1m³ cage and the feed ration was adjusted every 21 days with biometry. Data was collected from March to July (autumn and winter. Significant difference to final weight (P<0.05 among treatments was observed. The increase in feeding frequency improves the productive performance of Nile tilapias in cages and permitted better management of the food. The better feed conversion rate for high feeding frequency (24 times day-1 can result in saving up to 360kg of food for each ton of fish produced, increasing the economic sustenance for tilapia culture and suggesting less environmental pollution.

  13. CCAAT/enhancer binding protein β is dispensable for development of lung adenocarcinoma.

    Science.gov (United States)

    Cai, Yi; Hirata, Ayako; Nakayama, Sohei; VanderLaan, Paul A; Levantini, Elena; Yamamoto, Mihoko; Hirai, Hideyo; Wong, Kwok-Kin; Costa, Daniel B; Watanabe, Hideo; Kobayashi, Susumu S

    2015-01-01

    Lung cancer is the leading cause of cancer death worldwide. Although disruption of normal proliferation and differentiation is a vital component of tumorigenesis, the mechanisms of this process in lung cancer are still unclear. A transcription factor, C/EBPβ is a critical regulator of proliferation and/or differentiation in multiple tissues. In lung, C/EBPβ is expressed in alveolar pneumocytes and bronchial epithelial cells; however, its roles on normal lung homeostasis and lung cancer development have not been well described. Here we investigated whether C/EBPβ is required for normal lung development and whether its aberrant expression and/or activity contribute to lung tumorigenesis. We showed that C/EBPβ was expressed in both human normal pneumocytes and lung adenocarcinoma cell lines. We found that overall lung architecture was maintained in Cebpb knockout mice. Neither overexpression of nuclear C/EBPβ nor suppression of CEBPB expression had significant effects on cell proliferation. C/EBPβ expression and activity remained unchanged upon EGF stimulation. Furthermore, deletion of Cebpb had no impact on lung tumor burden in a lung specific, conditional mutant EGFR lung cancer mouse model. Analyses of data from The Cancer Genome Atlas (TCGA) revealed that expression, promoter methylation, or copy number of CEBPB was not significantly altered in human lung adenocarcinoma. Taken together, our data suggest that C/EBPβ is dispensable for development of lung adenocarcinoma.

  14. The JmjC domain of Gis1 is dispensable for transcriptional activation.

    Science.gov (United States)

    Yu, Yao; Neiman, Aaron M; Sternglanz, Rolf

    2010-11-01

    Yeast Gis1 protein functions as a transcription factor after nutrient limitation and oxidative stress. In this report, we show that Gis1 also regulates the induction of several genes involved in spore wall synthesis during sporulation. Gis1 contains a JmjC domain near its N-terminus. In many proteins, JmjC domains provide histone demethylase activity. Whether the JmjC domain of Gis1 contributes to its transcriptional activation is still unknown. Here, we show that gis1 point mutations that abolish Fe (II) and α-ketoglutarate binding, known cofactors in other JmjC proteins, are still able to induce transcription normally during glucose starvation and sporulation. Even the deletion of the entire JmjC domain does not affect transcriptional activation by Gis1. Moreover, the JmjC domain is not required for the toxicity associated with Gis1 overexpression. The data demonstrate that the JmjC domain is dispensable for transcriptional activation by Gis1 during nutrient stress and sporulation.

  15. Prescription, Dispensation, and Generic Medicine Replacement Ratios: Influence on Japanese Medicine Costs.

    Science.gov (United States)

    Yokoi, Masayuki; Tashiro, Takao

    2016-01-01

    This study used publicly available data to examine the effect of the separation of dispensing and prescribing medicines between pharmacists in pharmacies and doctors in medical institutions (the separation system) and the generic medicine replacement ratio on the cost of various medicines in Japanese prefectures. For Japanese medical institutions, participation in the separation system is optional. Consequently, the expansion rate of the separation system for each administrative district is highly variable. In our multiple regression analysis, the dependent variables were the costs of daily medicines, specifically, total, internal, external, and injection medicines, as well as medical devices, and the independent variables were the expansion rate of the separation system and generic medicine replacement ratio. The expansion rate of the separation system showed a significant negative partial correlation with the daily costs of total, internal, and injection medicines as well as medical devices. Moreover, the rate of replacing brand name medicines with generic medicines showed a significant negative partial correlation with the daily costs of total and internal medicines. However, external and injection medicines and medical devices did not because only a few or no generic products of these types were sold in the Japanese market. Otherwise, expansion of the separation system was effective in reducing medicine costs, except in the case of external medicines. This suggests that the cost efficiency effect of the separation system does not function all the time. PMID:26234979

  16. The way to reduce electrical charge of a droplet dispensed from a pipette tip

    Science.gov (United States)

    Choi, Dongwhi; Lee, Horim; Im, Do Jin; Kim, Dong Sung

    2013-11-01

    Recently, we reported that a conventional pipetting always makes a charged droplet by spontaneous electrical charging process. The charge amount depends on the constituents of the droplet, on coating material of pipette tip and on atmospheric humidity. We clarified that this natural electrification of a droplet is originated from the charge separation between a droplet and pipette tip surface. The electrical interaction between charged droplet hanging on the end of the pipette tip and the pipette tip inner surface makes the droplet hard to detach from the pipette tip. To suggest the way to suppress the electrification phenomenon, we investigate the influence of the polymer composition on the amount of the charge of the droplet. The Faraday cup method is performed to measure the charge amount of the droplet. The result can be used to reduce charge amount of a droplet dispensed from the micropipette tip effectively. This work was supported by the Mid-career Researcher Program No. 2011-0029454 funded by the Korea government (MEST).

  17. Understanding of pictograms from the United States Pharmacopeia Dispensing Information (USP-DI among elderly Brazilians

    Directory of Open Access Journals (Sweden)

    Barros IMC

    2014-10-01

    Full Text Available Izadora MC Barros, Thaciana S Alcântara, Alessandra R Mesquita, Monica L Bispo, Chiara E Rocha, Vagner Porto Moreira, Divaldo P Lyra Junior Laboratory of Teaching and Research in Social Pharmacy (LEPFS, Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Brazil Objective: To assess the understanding and cultural acceptability of the United States Pharmacopeia Dispensing Information (USP-DI in a group of elderly Brazilians.Methods: The study participants were individuals between 60 and 90 years old, of both sexes, with different levels of education and income. Fifteen of 81 pictograms from the USP-DI were presented to the elderly subjects, individually, without subtitles and in random order, so that the participants’ understanding of the pictograms could be evaluated.Results: The study included 116 participants. Only one of the selected pictograms reached the comprehension criterion established by the International Organization for Standardization 3864. With regard to the relationship between understanding and sociodemographic characteristics, age, wage income, and level of education were all found to be significantly associated with participants’ understanding of some of the pictograms.Conclusion: Most of the USP-DI pictograms evaluated were not well understood by the elderly Brazilians. This finding indicates that such pictograms need to be culturally adapted for the Brazilian context if they are to serve their purpose effectively in this country. Keywords: pictograms, understanding, elderly, Brazil

  18. WORK ANALYSIS OF DRUG-DISPENSING PROCESS IN A HOSPITAL EMERGENCY PHARMACY

    Directory of Open Access Journals (Sweden)

    Caroline Brum Rosso

    2016-03-01

    Full Text Available The work organization performs a crucial role in activities that involves problem resolution and decision making. A hospital emergency pharmacy consists in an example where the work environment has several kinds of demands that might be inconsistent and influenced by overcrowding – common situation in Brazilian hospitals – causing harm to work organization and suitability of workload. The objective of this study is to evaluate labor conditions of professionals that work in the emergency pharmacy of a university public hospital, seeking opportunities of improvement. A transversal study was developed with a descriptive character to analyze the work conditions. An ergonomic work analysis was conducted and, for the fulfillment of its steps, observations in loco were performed and methods Deparis, RULA and ABC analysis were used, pursuing to analyze data collected and rearranging the work situation. The findings allowed propositions of improvement, related mainly to the process of drug dispensation, organization and arrangement of the work environment. The ABC analysis presented itself as a valuable method for improving drugs organization in the pharmacy and might be useful in other work situations where accessibility of items is necessary, but many items must be positioned.

  19. PGC-1α is dispensable for exercise-induced mitochondrial biogenesis in skeletal muscle.

    Directory of Open Access Journals (Sweden)

    Glenn C Rowe

    Full Text Available Exercise confers numerous health benefits, many of which are thought to stem from exercise-induced mitochondrial biogenesis (EIMB in skeletal muscle. The transcriptional coactivator PGC-1α, a potent regulator of metabolism in numerous tissues, is widely believed to be required for EIMB. We show here that this is not the case. Mice engineered to lack PGC-1α specifically in skeletal muscle (Myo-PGC-1αKO mice retained intact EIMB. The exercise capacity of these mice was comparable to littermate controls. Induction of metabolic genes after 2 weeks of in-cage voluntary wheel running was intact. Electron microscopy revealed no gross abnormalities in mitochondria, and the mitochondrial biogenic response to endurance exercise was as robust in Myo-PGC-1αKO mice as in wildtype mice. The induction of enzymatic activity of the electron transport chain by exercise was likewise unperturbed in Myo-PGC-1αKO mice. These data demonstrate that PGC-1α is dispensable for exercise-induced mitochondrial biogenesis in skeletal muscle, in sharp contrast to the prevalent assumption in the field.

  20. Evaluation of Pharmacists' Services for Dispensing Emergency Contraceptive Pills in Delhi, India: A Mystery Shopper Study

    Science.gov (United States)

    Saxena, Pikee; Mishra, Archana; Nigam, Aruna

    2016-01-01

    Background: Although emergency contraceptive pills are available over the counter, the quality of consultation, including key areas of contraceptive counseling and prevention of sexually transmitted infections (STI), has not been well documented. Objective: To evaluate actual pharmacist services while dispensing emergency contraception through a mystery shopper technique. Material and Methods: This cross-sectional study was conducted in 81 pharmacies situated in Delhi by 4 trained mystery shoppers posed as customers over a period of 6 months. Results: None of the pharmacists asked about the time lapsed since last unprotected sexual intercourse or last menstrual period before deciding the eligibility of the customer. The majority were unclear about side effects associated with emergency contraception (78.57%) or with anticipated changes in menstrual flow (78.57%); 85.71% did not know whether subsequent unprotected intercourse would be protected. Only 15.71% counseled shoppers regarding risk of STI on asking leading questions and 88.5% did not provide any contraceptive advice. Conclusion: There is a huge gap in the technical knowledge and mindset of the pharmacists when it comes to checking for the eligibility of the client and providing advice regarding use of regular contraception and barrier for protection from STI, which needs to be addressed in order to realize the full benefit of making emergency contraceptive pills available over the counter. PMID:27385872