WorldWideScience

Sample records for acids research database

  1. Native Health Research Database

    Science.gov (United States)

    ... APP WITH JAVASCRIPT TURNED OFF. THE NATIVE HEALTH DATABASE REQUIRES JAVASCRIPT IN ORDER TO FUNCTION. PLEASE ENTER ... To learn more about searching the Native Health Database, click here. Keywords Title Author Source of Publication ...

  2. Database Research: Achievements and Challenges

    Institute of Scientific and Technical Information of China (English)

    Shan Wang; Xiao-Yong Du; Xiao-Feng Meng; Hong Chen

    2006-01-01

    Database system is the infrastructure of the modern information system. The R&D in the database system moves along by giant steps. This report presents the achievements Renmin University of China (RUC) has made in the past 25 years and at the same time addresses some of the research projects we, RUC, are currently working on. The National Natural Science Foundation of China supports and initiates most of our research projects and these successfully conducted projects have produced fruitful results.

  3. Biological Databases for Human Research

    Institute of Scientific and Technical Information of China (English)

    Dong Zou; Lina Ma; Jun Yu; Zhang Zhang

    2015-01-01

    The completion of the Human Genome Project lays a foundation for systematically studying the human genome from evolutionary history to precision medicine against diseases. With the explosive growth of biological data, there is an increasing number of biological databases that have been developed in aid of human-related research. Here we present a collection of human-related biological databases and provide a mini-review by classifying them into different categories according to their data types. As human-related databases continue to grow not only in count but also in volume, challenges are ahead in big data storage, processing, exchange and curation.

  4. Correlates of Access to Business Research Databases

    Science.gov (United States)

    Gottfried, John C.

    2010-01-01

    This study examines potential correlates of business research database access through academic libraries serving top business programs in the United States. Results indicate that greater access to research databases is related to enrollment in graduate business programs, but not to overall enrollment or status as a public or private institution.…

  5. Database Support for Research in Public Administration

    Science.gov (United States)

    Tucker, James Cory

    2005-01-01

    This study examines the extent to which databases support student and faculty research in the area of public administration. A list of journals in public administration, public policy, political science, public budgeting and finance, and other related areas was compared to the journal content list of six business databases. These databases…

  6. National Database for Autism Research (NDAR)

    Data.gov (United States)

    U.S. Department of Health & Human Services — National Database for Autism Research (NDAR) is an extensible, scalable informatics platform for austism spectrum disorder-relevant data at all levels of biological...

  7. Research reactor records in the INIS database

    International Nuclear Information System (INIS)

    This report presents a statistical analysis of more than 13,000 records of publications concerned with research and technology in the field of research and experimental reactors which are included in the INIS Bibliographic Database for the period from 1970 to 2001. The main objectives of this bibliometric study were: to make an inventory of research reactor related records in the INIS Database; to provide statistics and scientific indicators for the INIS users, namely science managers, researchers, engineers, operators, scientific editors and publishers, decision-makers in the field of research reactors related subjects; to extract other useful information from the INIS Bibliographic Database about articles published in research reactors research and technology. (author)

  8. NALDB: nucleic acid ligand database for small molecules targeting nucleic acid.

    Science.gov (United States)

    Kumar Mishra, Subodh; Kumar, Amit

    2016-01-01

    Nucleic acid ligand database (NALDB) is a unique database that provides detailed information about the experimental data of small molecules that were reported to target several types of nucleic acid structures. NALDB is the first ligand database that contains ligand information for all type of nucleic acid. NALDB contains more than 3500 ligand entries with detailed pharmacokinetic and pharmacodynamic information such as target name, target sequence, ligand 2D/3D structure, SMILES, molecular formula, molecular weight, net-formal charge, AlogP, number of rings, number of hydrogen bond donor and acceptor, potential energy along with their Ki, Kd, IC50 values. All these details at single platform would be helpful for the development and betterment of novel ligands targeting nucleic acids that could serve as a potential target in different diseases including cancers and neurological disorders. With maximum 255 conformers for each ligand entry, our database is a multi-conformer database and can facilitate the virtual screening process. NALDB provides powerful web-based search tools that make database searching efficient and simplified using option for text as well as for structure query. NALDB also provides multi-dimensional advanced search tool which can screen the database molecules on the basis of molecular properties of ligand provided by database users. A 3D structure visualization tool has also been included for 3D structure representation of ligands. NALDB offers an inclusive pharmacological information and the structurally flexible set of small molecules with their three-dimensional conformers that can accelerate the virtual screening and other modeling processes and eventually complement the nucleic acid-based drug discovery research. NALDB can be routinely updated and freely available on bsbe.iiti.ac.in/bsbe/naldb/HOME.php. Database URL: http://bsbe.iiti.ac.in/bsbe/naldb/HOME.php. PMID:26896846

  9. Research on computer virus database management system

    Science.gov (United States)

    Qi, Guoquan

    2011-12-01

    The growing proliferation of computer viruses becomes the lethal threat and research focus of the security of network information. While new virus is emerging, the number of viruses is growing, virus classification increasing complex. Virus naming because of agencies' capture time differences can not be unified. Although each agency has its own virus database, the communication between each other lacks, or virus information is incomplete, or a small number of sample information. This paper introduces the current construction status of the virus database at home and abroad, analyzes how to standardize and complete description of virus characteristics, and then gives the information integrity, storage security and manageable computer virus database design scheme.

  10. Databases and QSAR for Cancer Research

    Directory of Open Access Journals (Sweden)

    Adeel Malik

    2006-01-01

    Full Text Available In this review, we take a survey of bioinformatics databases and quantitative structure-activity relationship studies reported in published literature. Databases from the most general to special cancer-related ones have been included. Most commonly used methods of structure-based analysis of molecules have been reviewed, along with some case studies where they have been used in cancer research. This article is expected to be of use for general bioinformatics researchers interested in cancer and will also provide an update to those who have been actively pursuing this field of research.

  11. Emerging multidisciplinary research across database management systems

    CERN Document Server

    Nica, Anisoara; Varde, Aparna

    2011-01-01

    The database community is exploring more and more multidisciplinary avenues: Data semantics overlaps with ontology management; reasoning tasks venture into the domain of artificial intelligence; and data stream management and information retrieval shake hands, e.g., when processing Web click-streams. These new research avenues become evident, for example, in the topics that doctoral students choose for their dissertations. This paper surveys the emerging multidisciplinary research by doctoral students in database systems and related areas. It is based on the PIKM 2010, which is the 3rd Ph.D. workshop at the International Conference on Information and Knowledge Management (CIKM). The topics addressed include ontology development, data streams, natural language processing, medical databases, green energy, cloud computing, and exploratory search. In addition to core ideas from the workshop, we list some open research questions in these multidisciplinary areas.

  12. Emerging multidisciplinary research across database management systems

    OpenAIRE

    Nica, Anisoara; Suchanek, Fabian; Varde, Aparna

    2010-01-01

    The database community is exploring more and more multidisciplinary avenues: Data semantics overlaps with ontology management; reasoning tasks venture into the domain of artificial intelligence; and data stream management and information retrieval shake hands, e.g., when processing Web click-streams. These new research avenues become evident, for example, in the topics that doctoral students choose for their dissertations. This paper surveys the emerging multidisciplinary research by doctoral...

  13. CRITTER: A database for managing research animals

    OpenAIRE

    Lees, V. Wayne; Lukey, Claire; Orr, Richard

    1993-01-01

    We describe CRITTER, a computer database program for managing research animals. We designed it especially for institutions which operate health surveillance plans, such as specific pathogen-free schemes. Because CRITTER can be used to record any type of test result in any species of animal, it can be customized to suit each institution and its management protocol. In addition to maintaining a current inventory of each individual animal and its location, the program retains historical informat...

  14. Construction of databases: advances and significance in clinical research.

    Science.gov (United States)

    Long, Erping; Huang, Bingjie; Wang, Liming; Lin, Xiaoyu; Lin, Haotian

    2015-12-01

    Widely used in clinical research, the database is a new type of data management automation technology and the most efficient tool for data management. In this article, we first explain some basic concepts, such as the definition, classification, and establishment of databases. Afterward, the workflow for establishing databases, inputting data, verifying data, and managing databases is presented. Meanwhile, by discussing the application of databases in clinical research, we illuminate the important role of databases in clinical research practice. Lastly, we introduce the reanalysis of randomized controlled trials (RCTs) and cloud computing techniques, showing the most recent advancements of databases in clinical research. PMID:27215009

  15. Exhaustive Database Searching for Amino Acid Mutations in Proteomes

    Energy Technology Data Exchange (ETDEWEB)

    Hyatt, Philip Douglas [ORNL; Pan, Chongle [ORNL

    2012-01-01

    Amino acid mutations in proteins can be found by searching tandem mass spectra acquired in shotgun proteomics experiments against protein sequences predicted from genomes. Traditionally, unconstrained searches for amino acid mutations have been accomplished by using a sequence tagging approach that combines de novo sequencing with database searching. However, this approach is limited by the performance of de novo sequencing. The Sipros algorithm v2.0 was developed to perform unconstrained database searching using high-resolution tandem mass spectra by exhaustively enumerating all single non-isobaric mutations for every residue in a protein database. The performance of Sipros for amino acid mutation identification exceeded that of an established sequence tagging algorithm, Inspect, based on benchmarking results from a Rhodopseudomonas palustris proteomics dataset. To demonstrate the viability of the algorithm for meta-proteomics, Sipros was used to identify amino acid mutations in a natural microbial community in acid mine drainage.

  16. The CAP Theorem Versus Databases with Relaxed ACID properties

    DEFF Research Database (Denmark)

    Frank, Lars; Ulslev Pedersen, Rasmus; Frank, Christian Havnø;

    2014-01-01

    the traditional ACID properties and all the CAP properties were implemented. This optimizing is especially important in mobile integrated databases, where disconnections are normal and frequent. It is also important in distributed databases like EHR (electronic Health Records) where many different hospital...... data from different locations can have at most two of the three desirable CAP properties [5]. The NoSQL movement has applied the CAP theorem as an argument against traditional ACID (atomicity, consistency, isolation, and durability) databases, which prioritize consistency and partition...... availability and sufficient data consistency, despite the presence of network partitions. The overall objective of this paper is to improve the CAP optimization methods by using optimization techniques outside of those preferred in CAP optimization literature. The main contribution is to use relaxed ACID...

  17. Use of acid-suppressive drugs in pregnancy and the risk of childhood asthma : Bidirectional case-crossover study using the general practice research database

    NARCIS (Netherlands)

    Hak, Eelko; Mulder, Bianca; Schuiling-Veninga, Nynke C. M.; De Vries, Tjalling W.; Jick, Susan S.

    2013-01-01

    Background: Recent studies have reported an association between maternal use of gastric acid-suppressive drugs during pregnancy and asthma in the offspring, but the association could have been confounded by unmeasured risk factors. Objectives: To assess the association between the use of acid-suppre

  18. Use of Acid-Suppressive Drugs in Pregnancy and the Risk of Childhood Asthma : Bidirectional Crossover Study using the General Practice Research Database

    NARCIS (Netherlands)

    Hak, Eelko; Mulder, Bianca; Schuiling-Veninga, Catharina C. M.; de Vries, Tjalling W.; Jick, Susan S.

    2013-01-01

    Background Recent studies have reported an association between maternal use of gastric acid-suppressive drugs during pregnancy and asthma in the offspring, but the association could have been confounded by unmeasured risk factors. Objective We assessed the association between the use of acid-suppres

  19. Security Research on Engineering Database System

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Engine engineering database system is an oriented C AD applied database management system that has the capability managing distributed data. The paper discusses the security issue of the engine engineering database management system (EDBMS). Through studying and analyzing the database security, to draw a series of securi ty rules, which reach B1, level security standard. Which includes discretionary access control (DAC), mandatory access control (MAC) and audit. The EDBMS implem ents functions of DAC, ...

  20. Acid-suppressive drug use during pregnancy and the risk of atopic dermatitis : A crossover study within the clinical practice research database

    NARCIS (Netherlands)

    Mulder, Bianca; Hak, Eelko; Schuiling-Veninga, Catharina C.M.; De Vries, Tjalling W.; Jick, Susan S.

    2014-01-01

    Background: One previous study of our group reported that acid suppressive drug use during pregnancy is associated with an increased risk for the development of atopic dermatitis in children. However, reported associations could have been confounded by unmeasured risk factors. Objectives: The aim of

  1. Database use in psychiatric research: An international review

    Directory of Open Access Journals (Sweden)

    Nicola Higgins

    2005-03-01

    Full Text Available Objective: Whilst database use for the purposes of audit is well established amongst clinicians, their research potential has yet to be fully realised. This review provides an international perspective on research using databases in psychiatry, considering the advantages and constraints of their use. Method: Large databases used in psychiatric research were identified through a systematic search of MEDLINE and EMBASE databases. The types of research conducted with these databases were then grouped into categories for discussion. A narrative synthesis of results is presented, illustrated with examples. Results: Research identified included pharmacoepidemiology, perinatal, aetiological, suicidology and health service research. Conclusions: Databases have been used to address a range of questions in psychiatry, often by employing linkage between clinical and national administrative databases. The success of such research is not only dependent on appropriate methodology and database design, but also on clinician commitment to data entry. Further exploitation of linkage potential between databases is envisaged, alongside international development of clinical databases designed with the purpose of research in mind.

  2. Czech multicenter research database of severe COPD

    Directory of Open Access Journals (Sweden)

    Novotna B

    2014-11-01

    Full Text Available Barbora Novotna,1 Vladimir Koblizek,1 Jaromir Zatloukal,2 Marek Plutinsky,3 Karel Hejduk,4 Zuzana Zbozinkova,4 Jiri Jarkovsky,4 Ondrej Sobotik,5 Tomas Dvorak,6 Petr Safranek71Department of Pneumology, University Hospital Hradec Kralove, Charles University in Prague, Faculty of Medicine in Hradec Kralove, Hradec Kralove, 2Department of Pulmonology, University Hospital, Palacky University, Olomouc, 3Department of Pulmonology, University Hospital, Masaryk University, Brno, 4Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, 5Department of Pulmonology, University Hospital Motol, Charles University, Praha, 6Department of Pulmonology, Hospital Bulovka, Praha, 7Department of Pulmonology, University Hospital, Charles University, Plzen, the Czech RepublicPurpose: Chronic obstructive pulmonary disease (COPD has been recognized as a heterogeneous, multiple organ system-affecting disorder. The Global Initiative for Chronic Obstructive Lung Disease (GOLD places emphasis on symptom and exacerbation management. The aim of this study is examine the course of COPD and its impact on morbidity and all-cause mortality of patients, with respect to individual phenotypes and GOLD categories. This study will also evaluate COPD real-life patient care in the Czech Republic.Patients and methods: The Czech Multicentre Research Database of COPD is projected to last for 5 years, with the aim of enrolling 1,000 patients. This is a multicenter, observational, and prospective study of patients with severe COPD (post-bronchodilator forced expiratory volume in 1 second ≤60%. Every consecutive patient, who fulfils the inclusion criteria, is asked to participate in the study. Patient recruitment is done on the basis of signed informed consent. The study was approved by the Multicentre Ethical Committee in Brno, Czech Republic.Results: The objective of this paper was to outline the methodology of this study.Conclusion: The establishment of the

  3. Databases and registers: useful tools for research, no studies.

    Science.gov (United States)

    Curbelo, Rafael J; Loza, Estíbaliz; de Yébenes, Maria Jesús García; Carmona, Loreto

    2014-04-01

    There are many misunderstandings about databases. Database is a commonly misused term in reference to any set of data entered into a computer. However, true databases serve a main purpose, organising data. They do so by establishing several layers of relationships; databases are hierarchical. Databases commonly organise data over different levels and over time, where time can be measured as the time between visits, or between treatments, or adverse events, etc. In this sense, medical databases are closely related to longitudinal observational studies, as databases allow the introduction of data on the same patient over time. Basically, we could establish four types of databases in medicine, depending on their purpose: (1) administrative databases, (2) clinical databases, (3) registers, and (4) study-oriented databases. But a database is a useful tool for a large variety of studies, not a type of study itself. Different types of databases serve very different purposes, and a clear understanding of the different research designs mentioned in this paper would prevent many of the databases we launch from being just a lot of work and very little science. PMID:24509895

  4. Arabidopsis Hormone Database: a comprehensive genetic and phenotypic information database for plant hormone research in Arabidopsis

    OpenAIRE

    Peng, Zhi-Yu; Zhou, Xin; Li, Linchuan; Yu, Xiangchun; Li, Hongjiang; Jiang, Zhiqiang; Cao, Guangyu; Bai, Mingyi; Wang, Xingchun; Jiang, Caifu; Lu, Haibin; Hou, Xianhui; Qu, Lijia; Wang, Zhiyong; Zuo, Jianru

    2008-01-01

    Plant hormones are small organic molecules that influence almost every aspect of plant growth and development. Genetic and molecular studies have revealed a large number of genes that are involved in responses to numerous plant hormones, including auxin, gibberellin, cytokinin, abscisic acid, ethylene, jasmonic acid, salicylic acid, and brassinosteroid. Here, we develop an Arabidopsis hormone database, which aims to provide a systematic and comprehensive view of genes participating in plant h...

  5. Databases in the 3rd Millennium: Trends and Research Directions

    Directory of Open Access Journals (Sweden)

    Jaroslav Pokorny

    2010-04-01

    Full Text Available A database approach to data of arbitrary types has shown that the architecture of a universal database machine is restricting in a number of cases. There appear special-purpose data servers using now types of hardware devices. Data is moving toward the user, who exploits mobile devices equipped with database functionality. The goal of the paper is to present new trends in databases, particularly in their architectures and to show on cloud computing, data streams, mobile and embedded databases, and databases supporting Web.2.0 some new ideas and possibilities of solution of associated problems. The other goal of the paper is also to point out on actual problems associated with database research.

  6. Privacy and Data-Based Research

    OpenAIRE

    Ori Heffetz; Katrina Ligett

    2014-01-01

    What can we, as users of microdata, formally guarantee to the individuals (or firms) in our dataset, regarding their privacy? We retell a few stories, well-known in data-privacy circles, of failed anonymization attempts in publicly released datasets. We then provide a mostly informal introduction to several ideas from the literature on differential privacy, an active literature in computer science that studies formal approaches to preserving the privacy of individuals in statistical databases...

  7. Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research

    OpenAIRE

    Surati, Mosmi; Robinson, Matthew; Nandi, Suvobroto; Faoro, Leonardo; Demchuk, Carley; Kanteti, Rajani; Ferguson, Benjamin; Gangadhar, Tara; Hensing, Thomas; Hasina, Rifat; Husain, Aliya; Ferguson, Mark; Karrison, Theodore; Salgia, Ravi

    2011-01-01

    The Thoracic Oncology Program Database Project was created to serve as a comprehensive, verified, and accessible repository for well-annotated cancer specimens and clinical data to be available to researchers within the Thoracic Oncology Research Program. This database also captures a large volume of genomic and proteomic data obtained from various tumor tissue studies. A team of clinical and basic science researchers, a biostatistician, and a bioinformatics expert was convened to design the ...

  8. Business Faculty Research: Satisfaction with the Web versus Library Databases

    Science.gov (United States)

    Dewald, Nancy H.; Silvius, Matthew A.

    2005-01-01

    Business faculty members teaching at undergraduate campuses of the Pennsylvania State University were surveyed in order to assess their satisfaction with free Web sources and with subscription databases for their professional research. Although satisfaction with the Web's ease of use was higher than that for databases, overall satisfaction for…

  9. The Vocational Guidance Research Database: A Scientometric Approach

    Science.gov (United States)

    Flores-Buils, Raquel; Gil-Beltran, Jose Manuel; Caballer-Miedes, Antonio; Martinez-Martinez, Miguel Angel

    2012-01-01

    The scientometric study of scientific output through publications in specialized journals cannot be undertaken exclusively with the databases available today. For this reason, the objective of this article is to introduce the "Base de Datos de Investigacion en Orientacion Vocacional" [Vocational Guidance Research Database], based on the use of…

  10. Research on methods of designing and building digital seabed database

    Institute of Scientific and Technical Information of China (English)

    Su Tianyun; Liu Baohua; Zhai Shikui; Liang Ruicai; Zheng Yanpeng; Fu Qiang

    2007-01-01

    With a review of the recent development in digitalization and application of seabed data , this paper systematically proposed methods for integrating seabed data by analyzing its feature based on ORACLE database management system and advanced techniques of spatial data management. We did research on storage structure of seabed data, distributed- integrated database system, standardized spatial database and seabed metadata management system in order to effectively manage and use these seabed information in practical application . Finally , we applied the methods researched and proposed in this paper to build the Bohai Sea engineering geology database that stores engineering geology data and other seabed information from the Bohai Sea area . As a result , the Bohai Sea engineering geology database can effectively integrate huge amount of distributed and complicated seabed data to meet the practical requisition of Bohai Sea engineering geology environment exploration and exploitation.

  11. Databases for multilevel biophysiology research available at Physiome.jp

    Directory of Open Access Journals (Sweden)

    Yoshiyuki eAsai

    2015-09-01

    Full Text Available Physiome.jp (http://physiome.jp is a portal site inaugurated in 2007 to support model-based research in physiome and systems biology. At Physiome.jp, several tools and databases are available to support construction of physiological, multi-hierarchical, large-scale models. There are three databases in Physiome.jp, housing mathematical models, morphological data, and time-series data. In late 2013, the site was fully renovated, and in May 2015, new functions were implemented to provide information infrastructure to support collaborative activities for developing models and performing simulations within the database framework. This article describes updates to the databases implemented since 2013, including cooperation among the three databases, interactive model browsing, user management, version management of models, management of parameter sets, and interoperability with applications.

  12. Fedora Content Modelling for Improved Services for Research Databases

    DEFF Research Database (Denmark)

    Elbæk, Mikael Karstensen; Heller, Alfred; Pedersen, Gert Schmeltz

    A re-implementation of the research database of the Technical University of Denmark, DTU, is based on Fedora. The backbone consists of content models for primary and secondary entities and their relationships, giving flexible and powerful extraction capabilities for interoperability and reporting....... By adopting such an abstract data model, the platform enables new and improved services for researchers, librarians and administrators....

  13. Fusion research and technology records in INIS database

    International Nuclear Information System (INIS)

    This article is a summary of a survey study ''''A survey on publications in Fusion Research and Technology. Science and Technology Indicators in Fusion R and T'''' by the same author on Fusion R and T records in the International Nuclear Information System (INIS) bibliographic database. In that study, for the first time, all scientometric and bibliometric information contained in a bibliographic database, using INIS records, is analyzed and quantified, specific to a selected field of science and technology. A variety of new science and technology indicators which can be used for evaluating research and development activities is also presented in that study that study

  14. Databases

    Data.gov (United States)

    National Aeronautics and Space Administration — The databases of computational and experimental data from the first Aeroelastic Prediction Workshop are located here. The databases file names tell their contents...

  15. Databases

    Digital Repository Service at National Institute of Oceanography (India)

    Kunte, P.D.

    Information on bibliographic as well as numeric/textual databases relevant to coastal geomorphology has been included in a tabular form. Databases cover a broad spectrum of related subjects like coastal environment and population aspects, coastline...

  16. A lexical database tool for quantitative phonological research

    CERN Document Server

    Bird, S D

    1999-01-01

    A lexical database tool tailored for phonological research is described. Database fields include transcriptions, glosses and hyperlinks to speech files. Database queries are expressed using HTML forms, and these permit regular expression search on any combination of fields. Regular expressions are passed directly to a Perl CGI program, enabling the full flexibility of Perl extended regular expressions. The regular expression notation is extended to better support phonological searches, such as search for minimal pairs. Search results are presented in the form of HTML or LaTeX tables, where each cell is either a number (representing frequency) or a designated subset of the fields. Tables have up to four dimensions, with an elegant system for specifying which fragments of which fields should be used for the row/column labels. The tool offers several advantages over traditional methods of analysis: (i) it supports a quantitative method of doing phonological research; (ii) it gives universal access to the same se...

  17. Current research status, databases and application of single nucleotide polymorphism.

    Science.gov (United States)

    Javed, R; Mukesh

    2010-07-01

    Single Nucleotide Polymorphisms (SNPs) are the most frequent form of DNA variation in the genome. SNPs are genetic markers which are bi-allelic in nature and grow at a very fast rate. Current genomic databases contain information on several million SNPs. More than 6 million SNPs have been identified and the information is publicly available through the efforts of the SNP Consortium and others data bases. The NCBI plays a major role in facillating the identification and cataloging of SNPs through creation and maintenance of the public SNP database (dbSNP) by the biomedical community worldwide and stimulate many areas of biological research including the identification of the genetic components of disease. In this review article, we are compiling the existing SNP databases, research status and their application. PMID:21717869

  18. Arabidopsis Hormone Database: a comprehensive genetic and phenotypic information database for plant hormone research in Arabidopsis.

    Science.gov (United States)

    Peng, Zhi-yu; Zhou, Xin; Li, Linchuan; Yu, Xiangchun; Li, Hongjiang; Jiang, Zhiqiang; Cao, Guangyu; Bai, Mingyi; Wang, Xingchun; Jiang, Caifu; Lu, Haibin; Hou, Xianhui; Qu, Lijia; Wang, Zhiyong; Zuo, Jianru; Fu, Xiangdong; Su, Zhen; Li, Songgang; Guo, Hongwei

    2009-01-01

    Plant hormones are small organic molecules that influence almost every aspect of plant growth and development. Genetic and molecular studies have revealed a large number of genes that are involved in responses to numerous plant hormones, including auxin, gibberellin, cytokinin, abscisic acid, ethylene, jasmonic acid, salicylic acid, and brassinosteroid. Here, we develop an Arabidopsis hormone database, which aims to provide a systematic and comprehensive view of genes participating in plant hormonal regulation, as well as morphological phenotypes controlled by plant hormones. Based on data from mutant studies, transgenic analysis and gene ontology (GO) annotation, we have identified a total of 1026 genes in the Arabidopsis genome that participate in plant hormone functions. Meanwhile, a phenotype ontology is developed to precisely describe myriad hormone-regulated morphological processes with standardized vocabularies. A web interface (http://ahd.cbi.pku.edu.cn) would allow users to quickly get access to information about these hormone-related genes, including sequences, functional category, mutant information, phenotypic description, microarray data and linked publications. Several applications of this database in studying plant hormonal regulation and hormone cross-talk will be presented and discussed. PMID:19015126

  19. GiSAO.db: a database for ageing research

    Directory of Open Access Journals (Sweden)

    Grillari Johannes

    2011-05-01

    Full Text Available Abstract Background Age-related gene expression patterns of Homo sapiens as well as of model organisms such as Mus musculus, Saccharomyces cerevisiae, Caenorhabditis elegans and Drosophila melanogaster are a basis for understanding the genetic mechanisms of ageing. For an effective analysis and interpretation of expression profiles it is necessary to store and manage huge amounts of data in an organized way, so that these data can be accessed and processed easily. Description GiSAO.db (Genes involved in senescence, apoptosis and oxidative stress database is a web-based database system for storing and retrieving ageing-related experimental data. Expression data of genes and miRNAs, annotation data like gene identifiers and GO terms, orthologs data and data of follow-up experiments are stored in the database. A user-friendly web application provides access to the stored data. KEGG pathways were incorporated and links to external databases augment the information in GiSAO.db. Search functions facilitate retrieval of data which can also be exported for further processing. Conclusions We have developed a centralized database that is very well suited for the management of data for ageing research. The database can be accessed at https://gisao.genome.tugraz.at and all the stored data can be viewed with a guest account.

  20. Gas Hydrate Research Database and Web Dissemination Channel

    Energy Technology Data Exchange (ETDEWEB)

    Micheal Frenkel; Kenneth Kroenlein; V Diky; R.D. Chirico; A. Kazakow; C.D. Muzny; M. Frenkel

    2009-09-30

    To facilitate advances in application of technologies pertaining to gas hydrates, a United States database containing experimentally-derived information about those materials was developed. The Clathrate Hydrate Physical Property Database (NIST Standard Reference Database {number_sign} 156) was developed by the TRC Group at NIST in Boulder, Colorado paralleling a highly-successful database of thermodynamic properties of molecular pure compounds and their mixtures and in association with an international effort on the part of CODATA to aid in international data sharing. Development and population of this database relied on the development of three components of information-processing infrastructure: (1) guided data capture (GDC) software designed to convert data and metadata into a well-organized, electronic format, (2) a relational data storage facility to accommodate all types of numerical and metadata within the scope of the project, and (3) a gas hydrate markup language (GHML) developed to standardize data communications between 'data producers' and 'data users'. Having developed the appropriate data storage and communication technologies, a web-based interface for both the new Clathrate Hydrate Physical Property Database, as well as Scientific Results from the Mallik 2002 Gas Hydrate Production Research Well Program was developed and deployed at http://gashydrates.nist.gov.

  1. A relational database application in support of integrated neuroscience research.

    Science.gov (United States)

    Rudowsky, Ira; Kulyba, Olga; Kunin, Mikhail; Ogarodnikov, Dmitri; Raphan, Theodore

    2004-12-01

    The development of relational databases has significantly improved the performance of storage, search, and retrieval functions and has made it possible for applications that perform real-time data acquisition and analysis to interact with these types of databases. The purpose of this research was to develop a user interface for interaction between a data acquisition and analysis application and a relational database using the Oracle9i system. The overall system was designed to have an indexing capability that threads into the data acquisition and analysis programs. Tables were designed and relations within the database for indexing the files and information contained within the files were established. The system provides retrieval capabilities over a broad range of media, including analog, event, and video data types. The system's ability to interact with a data capturing program at the time of the experiment to create both multimedia files as well as the meta-data entries in the relational database avoids manual entries in the database and ensures data integrity and completeness for further interaction with the data by analysis applications. PMID:15657974

  2. DANBIO-powerful research database and electronic patient record

    DEFF Research Database (Denmark)

    Hetland, Merete Lund

    2011-01-01

    The nationwide DANBIO registry has been designed to capture operational clinical data as part of routine clinical care. At the same time, it provides a powerful research database. This article reviews the DANBIO registry with focus on problems and solutions of design, funding and linkage, provides...

  3. About the database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The journal of Meteorological and Environmental Research [ISSN: 2152 -3940]has been included and stored by four fa-mous databases: CAS,CABI,CSA and CNKI.CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive

  4. About the database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The journal of Meteorological and Environmental Research[ISSN:2152-3940] has been included and stored by four famous databases:CAS,CABI,CSA and CNKI.CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive

  5. RepSeq – A database of amino acid repeats present in lower eukaryotic pathogens

    Directory of Open Access Journals (Sweden)

    Smith Deborah F

    2007-04-01

    Full Text Available Abstract Background Amino acid repeat-containing proteins have a broad range of functions and their identification is of relevance to many experimental biologists. In human-infective protozoan parasites (such as the Kinetoplastid and Plasmodium species, they are implicated in immune evasion and have been shown to influence virulence and pathogenicity. RepSeq http://repseq.gugbe.com is a new database of amino acid repeat-containing proteins found in lower eukaryotic pathogens. The RepSeq database is accessed via a web-based application which also provides links to related online tools and databases for further analyses. Results The RepSeq algorithm typically identifies more than 98% of repeat-containing proteins and is capable of identifying both perfect and mismatch repeats. The proportion of proteins that contain repeat elements varies greatly between different families and even species (3–35% of the total protein content. The most common motif type is the Sequence Repeat Region (SRR – a repeated motif containing multiple different amino acid types. Proteins containing Single Amino Acid Repeats (SAARs and Di-Peptide Repeats (DPRs typically account for 0.5–1.0% of the total protein number. Notable exceptions are P. falciparum and D. discoideum, in which 33.67% and 34.28% respectively of the predicted proteomes consist of repeat-containing proteins. These numbers are due to large insertions of low complexity single and multi-codon repeat regions. Conclusion The RepSeq database provides a repository for repeat-containing proteins found in parasitic protozoa. The database allows for both individual and cross-species proteome analyses and also allows users to upload sequences of interest for analysis by the RepSeq algorithm. Identification of repeat-containing proteins provides researchers with a defined subset of proteins which can be analysed by expression profiling and functional characterisation, thereby facilitating study of pathogenicity

  6. Databases

    Directory of Open Access Journals (Sweden)

    Nick Ryan

    2004-01-01

    Full Text Available Databases are deeply embedded in archaeology, underpinning and supporting many aspects of the subject. However, as well as providing a means for storing, retrieving and modifying data, databases themselves must be a result of a detailed analysis and design process. This article looks at this process, and shows how the characteristics of data models affect the process of database design and implementation. The impact of the Internet on the development of databases is examined, and the article concludes with a discussion of a range of issues associated with the recording and management of archaeological data.

  7. Concierge: Personal database software for managing digital research resources

    Directory of Open Access Journals (Sweden)

    Hiroyuki Sakai

    2007-11-01

    Full Text Available This article introduces a desktop application, named Concierge, for managing personal digital research resources. Using simple operations, it enables storage of various types of files and indexes them based on content descriptions. A key feature of the software is a high level of extensibility. By installing optional plug-ins, users can customize and extend the usability of the software based on their needs. In this paper, we also introduce a few optional plug-ins: literaturemanagement, electronic laboratory notebook, and XooNlps client plug-ins. XooNIps is a content management system developed to share digital research resources among neuroscience communities. It has been adopted as the standard database system in Japanese neuroinformatics projects. Concierge, therefore, offers comprehensive support from management of personal digital research resources to their sharing in open-access neuroinformatics databases such as XooNIps. This interaction between personal and open-access neuroinformatics databases is expected to enhance the dissemination of digital research resources. Concierge is developed as an open source project; Mac OS X and Windows XP versions have been released at the official site (http://concierge.sourceforge.jp.

  8. [Benefits of large healthcare databases for drug risk research].

    Science.gov (United States)

    Garbe, Edeltraut; Pigeot, Iris

    2015-08-01

    Large electronic healthcare databases have become an important worldwide data resource for drug safety research after approval. Signal generation methods and drug safety studies based on these data facilitate the prospective monitoring of drug safety after approval, as has been recently required by EU law and the German Medicines Act. Despite its large size, a single healthcare database may include insufficient patients for the study of a very small number of drug-exposed patients or the investigation of very rare drug risks. For that reason, in the United States, efforts have been made to work on models that provide the linkage of data from different electronic healthcare databases for monitoring the safety of medicines after authorization in (i) the Sentinel Initiative and (ii) the Observational Medical Outcomes Partnership (OMOP). In July 2014, the pilot project Mini-Sentinel included a total of 178 million people from 18 different US databases. The merging of the data is based on a distributed data network with a common data model. In the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCEPP) there has been no comparable merging of data from different databases; however, first experiences have been gained in various EU drug safety projects. In Germany, the data of the statutory health insurance providers constitute the most important resource for establishing a large healthcare database. Their use for this purpose has so far been severely restricted by the Code of Social Law (Section 75, Book 10). Therefore, a reform of this section is absolutely necessary. PMID:26092163

  9. Systematically retrieving research – a case study evaluating seven databases.

    OpenAIRE

    Taylor, B.J.; Wylie, E.; Dempster, Martin; Donnelly, Michael

    2007-01-01

    Objective: Developing the scientific underpinnings of social welfare requires effective and efficient methods of retrieving relevant items from the increasing volume of research. Method: We compared seven databases by running the nearest equivalent search on each. The search topic was chosen for relevance to social work practice with older people. Results: Highest sensitivity was achieved by Medline (52%), Social Sciences Citation Index (46%) and Cumulative Index of Nursing and Allied Health ...

  10. About the Database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    正The journal of Meteorological and Environmental Research [ISSN: 2152-3940] has been included and stored by five famous databases:CAS,CABI,CSA,EBSCO and CNKI. CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive source for chemical information. Centre for Agriculture and Bioscience International(CABI) is a not-for-profit international

  11. About the Database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    The journal of Meteorological and Environmental Research [ISSN: 2152-3940] has been included and stored by five famous databases:CAS,CABI,CSA,EBSCO and CNKI. CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive source for chemical information. Centre for Agriculture and Bioscience International(CABI) is a not-for-profit international

  12. XML Database Researching%XML数据库技术研究

    Institute of Scientific and Technical Information of China (English)

    秦杰; 杨树强; 窦文华

    2003-01-01

    XML database is a new database technology. This paper gives an overview about the last research aboutXML database and its related productions,then comparing XML database with traditional RDBMS. We analyze andpoint out some weaknesses about XML database,and give out our viewpoint.

  13. A neuroinformatics database system for disease-oriented neuroimaging research.

    Science.gov (United States)

    Wong, Stephen T C; Hoo, Kent Soo; Cao, Xinhua; Tjandra, Donny; Fu, J C; Dillon, William P

    2004-03-01

    Clinical databases are continually growing and accruing more patient information. One of the challenges for managing this wealth of data is efficient retrieval and analysis of a broad range of image and non-image patient data from diverse data sources. This article describes the design and implementation of a new class of research data warehouse, neuroinformatics database system (NIDS), which will alleviate these problems for clinicians and researchers studying and treating patients with intractable temporal lobe epilepsy. The NIDS is a secured, multi-tier system that enables the user to gather, proofread, analyze, and store data from multiple underlying sources. In addition to data management, the NIDS provides several key functions including image analysis and processing, free text search of patient reports, construction of general queries, and on-line statistical analysis. The establishment of this integrated research database will serve as a foundation for future hypothesis-driven experiments, which could uncover previously unsuspected correlations and perhaps help to identify new and accurate predictors for image diagnosis.

  14. BAO Plate Archive Project: Digitization, Electronic Database and Research Programmes

    Science.gov (United States)

    Mickaelian, A. M.; Abrahamyan, H. V.; Andreasyan, H. R.; Azatyan, N. M.; Farmanyan, S. V.; Gigoyan, K. S.; Gyulzadyan, M. V.; Khachatryan, K. G.; Knyazyan, A. V.; Kostandyan, G. R.; Mikayelyan, G. A.; Nikoghosyan, E. H.; Paronyan, G. M.; Vardanyan, A. V.

    2016-06-01

    The most important part of the astronomical observational heritage are astronomical plate archives created on the basis of numerous observations at many observatories. Byurakan Astrophysical Observatory (BAO) plate archive consists of 37,000 photographic plates and films, obtained at 2.6m telescope, 1m and 0.5m Schmidt type and other smaller telescopes during 1947-1991. In 2002-2005, the famous Markarian Survey (also called First Byurakan Survey, FBS) 1874 plates were digitized and the Digitized FBS (DFBS) was created. New science projects have been conducted based on these low-dispersion spectroscopic material. A large project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage was started in 2015. A Science Program Board is created to evaluate the observing material, to investigate new possibilities and to propose new projects based on the combined usage of these observations together with other world databases. The Executing Team consists of 11 astronomers and 2 computer scientists and will use 2 EPSON Perfection V750 Pro scanners for the digitization, as well as Armenian Virtual Observatory (ArVO) database will be used to accommodate all new data. The project will run during 3 years in 2015-2017 and the final result will be an electronic database and online interactive sky map to be used for further research projects, mainly including high proper motion stars, variable objects and Solar System bodies.

  15. DANBIO--powerful research database and electronic patient record.

    Science.gov (United States)

    Hetland, Merete Lund

    2011-01-01

    The nationwide DANBIO registry has been designed to capture operational clinical data as part of routine clinical care. At the same time, it provides a powerful research database. This article reviews the DANBIO registry with focus on problems and solutions of design, funding and linkage, provides an overview of the research outcome and presents the cohorts of RA patients. The registry, which is approved as a national quality registry, includes patients with RA, PsA and AS, who are followed longitudinally. Data are captured electronically from the source (patients and health personnel). The IT platform is based on open-source software. Via a unique personal identification code, linkage with various national registers is possible for research purposes. Since the year 2000, more than 10,000 patients have been included. The main focus of research has been on treatment efficacy and drug survival. Compared with RA patients, who were on conventional treatment with DMARDs, the patients who started biological treatment were younger, had longer disease duration, higher disease activity, tried more DMARDs and received more prednisolone. Also, more patients on biological therapy were seropositive and had erosive disease. However, the current levels of disease activities and the fraction of patients who had gone into remission in the two groups of patients were very similar. This indicates that clinicians have a common treatment goal for RA patients regardless of treatment. In conclusion, DANBIO serves as an electronic patient 'chronicle' in routine care, and at the same time provides a powerful research database. PMID:21148154

  16. U.S. Army Research Laboratory (ARL) multimodal signatures database

    Science.gov (United States)

    Bennett, Kelly

    2008-04-01

    The U.S. Army Research Laboratory (ARL) Multimodal Signatures Database (MMSDB) is a centralized collection of sensor data of various modalities that are co-located and co-registered. The signatures include ground and air vehicles, personnel, mortar, artillery, small arms gunfire from potential sniper weapons, explosives, and many other high value targets. This data is made available to Department of Defense (DoD) and DoD contractors, Intel agencies, other government agencies (OGA), and academia for use in developing target detection, tracking, and classification algorithms and systems to protect our Soldiers. A platform independent Web interface disseminates the signatures to researchers and engineers within the scientific community. Hierarchical Data Format 5 (HDF5) signature models provide an excellent solution for the sharing of complex multimodal signature data for algorithmic development and database requirements. Many open source tools for viewing and plotting HDF5 signatures are available over the Web. Seamless integration of HDF5 signatures is possible in both proprietary computational environments, such as MATLAB, and Free and Open Source Software (FOSS) computational environments, such as Octave and Python, for performing signal processing, analysis, and algorithm development. Future developments include extending the Web interface into a portal system for accessing ARL algorithms and signatures, High Performance Computing (HPC) resources, and integrating existing database and signature architectures into sensor networking environments.

  17. The FoodCast Research Image Database (FRIDa

    Directory of Open Access Journals (Sweden)

    Francesco eForoni

    2013-03-01

    Full Text Available In recent years we have witnessed to an increasing interest in food processing and eating behaviors. This is probably due to several reasons. The biological relevance of food choices, the complexity of the food-rich environment in which we presently live (making food-intake regulation difficult, and the increasing health care cost due to illness associated with food (food hazards, food contamination, and aberrant food-intake. Despite the importance of the issues and the relevance of this research, comprehensive and validated databases of stimuli are rather limited, outdated, or not available for noncommercial purposes to independent researchers who aim at developing their own research program. The FoodCast Research Image Database (FRIDa we present here is comprised of 877 images from eight different categories: natural-food (e.g., strawberry, transformed-food (e.g., French fries, rotten-food (e.g., moldy banana, natural-nonfood items (e.g., pinecone, artificial food-related objects (e.g., teacup, artificial objects (e.g., guitar, animals (e.g., camel, and scenes (e.g., airport. FRIDa has been validated on a sample of healthy participants (N=73 on standard variables (e.g., valence, familiarity etc. as well as on other variables specifically related to food items (e.g., perceived calorie content; it also includes data on the visual features of the stimuli (e.g., brightness, high frequency power etc.. FRIDa is a well-controlled, flexible, validated, and freely available (http://foodcast.sissa.it/neuroscience/ tool for researchers in a wide range of academic fields and industry.

  18. Geo-scientific database for research and development purposes

    International Nuclear Information System (INIS)

    Document available in extended abstract form only. The Research and Development Division must manage, secure and reliable manner, a large number of data from scientific disciplines and diverse means of acquisition (observations, measurements, experiments, etc.). This management is particularly important for the Underground research Laboratory, the source of many recording continuous measurements. Thus, from its conception, Andra has implemented two management tools of scientific information, the 'Acquisition System and Data Management' [SAGD] and GEO database with its associated applications. Beyond its own needs, Andra wants to share its achievements with the scientific community, and it therefore provides the data stored in its databases or samples of rock or water when they are available. Acquisition and Data Management (SAGD) This system manages data from sensors installed at several sites. Some sites are on the surface (piezometric, atmospheric and environmental stations), the other are in the Underground Research Laboratory. This system also incorporates data from experiments in which Andra participates in Mont Terri Laboratory in Switzerland. S.A.G.D fulfils these objectives by: - Make available in real time on a single system, with scientists from Andra but also different partners or providers who need it, all experimental data from measurement points - Displaying the recorded data on temporal windows and specific time step, - Allowing remote control of the experimentations, - Ensuring the traceability of all recorded information, - Ensuring data storage in a data base. S.A.G.D has been deployed in the first experimental drift at -445 m in November 2004. It was subsequently extended to the underground Mont Terri laboratory in Switzerland in 2005, to the entire surface logging network of the Meuse / Haute-Marne Center in 2008 and to the environmental network in 2011. All information is acquired, stored and manage by a software called Geoscope. This software

  19. Knowledge map of artemisinin research in SCI and Medline database

    Directory of Open Access Journals (Sweden)

    Qiang Yao , Jing Chen , Peng-Hui Lyu , Shi-Jing Zhang , Fei-Cheng Ma & Jian-Guo Fang

    2012-12-01

    Full Text Available Background & objectives: Artemisinin was first extracted from the herb Artemisia annua which has been used formany centuries in Chinese traditional medicine as a treatment for fever and malaria. It has been given the 2011Lasker-DeBakey clinical medical research award. In this paper, knowledge map of artemisinin research wasdrawn to provide some information for global researchers interested in artemisinin and its relevant references.Methods: In this work, bibliometric analysis and knowledge visualization technology were applied to evaluateglobal scientific production and developing trend of artemisinin research through Science Citation Index (SCIpapers and Medline papers with online version published as following aspects: publication outputs, subjectcategories, journals, countries, international collaboration, citations, authorship and co-authorship, author keywords and co-words analysis. The Thomson Data Analyzer (TDA, Netdraw and Aureka software were employedto analyze the SCI as well as Medline papers data for knowledge mapping.Results: Global literature of artemisinin research has increased rapidly over the past 30 years and has boosted inrecent years. Seen from the statistical study in many aspects, Pharmacology & Pharmacy, and Chemistry are stillthe main subjects of artemisinin research with parasitology and tropical medicine increasing quickly. MalariaJournal and American Journal of Tropical Medicine are top productive journals both in SCI and Medline databases.Quantity and quality of papers in US are in a leading position, although papers quantity and active degree indeveloping countries such as P.R. China, Thailand and India are relatively high, the quality of papers from thesecountries needs to be improved. New emerging key words and co-words remind us that mechanism of action,pharmacokinetics, artemisinin-based alternatives, etc. are the future trends of artemisinin research.Conclusion: Through bibliometric analysis the development

  20. Intra-disciplinary differences in database coverage and the consequences for bibliometric research

    DEFF Research Database (Denmark)

    Faber Frandsen, Tove; Nicolaisen, Jeppe

    2008-01-01

    Bibliographic databases (including databases based on open access) are routinely used for bibliometric research. The value of a specific database depends to a large extent on the coverage of the discipline(s) under study. A number of studies have determined the coverage of databases in specific...... and psychology). The point extends to include both the uneven coverage of specialties and research traditions. The implications for bibliometric research are discussed, and precautions which need to be taken are outlined. ...

  1. TB database: an integrated platform for tuberculosis research.

    Science.gov (United States)

    Reddy, T B K; Riley, Robert; Wymore, Farrell; Montgomery, Phillip; DeCaprio, Dave; Engels, Reinhard; Gellesch, Marcel; Hubble, Jeremy; Jen, Dennis; Jin, Heng; Koehrsen, Michael; Larson, Lisa; Mao, Maria; Nitzberg, Michael; Sisk, Peter; Stolte, Christian; Weiner, Brian; White, Jared; Zachariah, Zachariah K; Sherlock, Gavin; Galagan, James E; Ball, Catherine A; Schoolnik, Gary K

    2009-01-01

    The effective control of tuberculosis (TB) has been thwarted by the need for prolonged, complex and potentially toxic drug regimens, by reliance on an inefficient vaccine and by the absence of biomarkers of clinical status. The promise of the genomics era for TB control is substantial, but has been hindered by the lack of a central repository that collects and integrates genomic and experimental data about this organism in a way that can be readily accessed and analyzed. The Tuberculosis Database (TBDB) is an integrated database providing access to TB genomic data and resources, relevant to the discovery and development of TB drugs, vaccines and biomarkers. The current release of TBDB houses genome sequence data and annotations for 28 different Mycobacterium tuberculosis strains and related bacteria. TBDB stores pre- and post-publication gene-expression data from M. tuberculosis and its close relatives. TBDB currently hosts data for nearly 1500 public tuberculosis microarrays and 260 arrays for Streptomyces. In addition, TBDB provides access to a suite of comparative genomics and microarray analysis software. By bringing together M. tuberculosis genome annotation and gene-expression data with a suite of analysis tools, TBDB (http://www.tbdb.org/) provides a unique discovery platform for TB research. PMID:18835847

  2. University Real Estate Development Database: A Database-Driven Internet Research Tool

    Science.gov (United States)

    Wiewel, Wim; Kunst, Kara

    2008-01-01

    The University Real Estate Development Database is an Internet resource developed by the University of Baltimore for the Lincoln Institute of Land Policy, containing over six hundred cases of university expansion outside of traditional campus boundaries. The University Real Estate Development database is a searchable collection of real estate…

  3. The GUDMAP database--an online resource for genitourinary research.

    Science.gov (United States)

    Harding, Simon D; Armit, Chris; Armstrong, Jane; Brennan, Jane; Cheng, Ying; Haggarty, Bernard; Houghton, Derek; Lloyd-MacGilp, Sue; Pi, Xingjun; Roochun, Yogmatee; Sharghi, Mehran; Tindal, Christopher; McMahon, Andrew P; Gottesman, Brian; Little, Melissa H; Georgas, Kylie; Aronow, Bruce J; Potter, S Steven; Brunskill, Eric W; Southard-Smith, E Michelle; Mendelsohn, Cathy; Baldock, Richard A; Davies, Jamie A; Davidson, Duncan

    2011-07-01

    The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research. PMID:21652655

  4. The GUDMAP database – an online resource for genitourinary research

    Science.gov (United States)

    Harding, Simon D.; Armit, Chris; Armstrong, Jane; Brennan, Jane; Cheng, Ying; Haggarty, Bernard; Houghton, Derek; Lloyd-MacGilp, Sue; Pi, Xingjun; Roochun, Yogmatee; Sharghi, Mehran; Tindal, Christopher; McMahon, Andrew P.; Gottesman, Brian; Little, Melissa H.; Georgas, Kylie; Aronow, Bruce J.; Potter, S. Steven; Brunskill, Eric W.; Southard-Smith, E. Michelle; Mendelsohn, Cathy; Baldock, Richard A.; Davies, Jamie A.; Davidson, Duncan

    2011-01-01

    The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research. PMID:21652655

  5. APD3: the antimicrobial peptide database as a tool for research and education.

    Science.gov (United States)

    Wang, Guangshun; Li, Xia; Wang, Zhe

    2016-01-01

    The antimicrobial peptide database (APD, http://aps.unmc.edu/AP/) is an original database initially online in 2003. The APD2 (2009 version) has been regularly updated and further expanded into the APD3. This database currently focuses on natural antimicrobial peptides (AMPs) with defined sequence and activity. It includes a total of 2619 AMPs with 261 bacteriocins from bacteria, 4 AMPs from archaea, 7 from protists, 13 from fungi, 321 from plants and 1972 animal host defense peptides. The APD3 contains 2169 antibacterial, 172 antiviral, 105 anti-HIV, 959 antifungal, 80 antiparasitic and 185 anticancer peptides. Newly annotated are AMPs with antibiofilm, antimalarial, anti-protist, insecticidal, spermicidal, chemotactic, wound healing, antioxidant and protease inhibiting properties. We also describe other searchable annotations, including target pathogens, molecule-binding partners, post-translational modifications and animal models. Amino acid profiles or signatures of natural AMPs are important for peptide classification, prediction and design. Finally, we summarize various database applications in research and education. PMID:26602694

  6. Research Note on the Energy Infrastructure Attack Database (EIAD

    Directory of Open Access Journals (Sweden)

    Jennifer Giroux

    2013-12-01

    Full Text Available The January 2013 attack on the In Amenas natural gas facility drew international attention. However this attack is part of a portrait of energy infrastructure targeting by non-state actors that spans the globe. Data drawn from the Energy Infrastructure Attack Database (EIAD shows that in the last decade there were, on average, nearly 400 annual attacks carried out by armed non-state actors on energy infrastructure worldwide, a figure that was well under 200 prior to 1999. This data reveals a global picture whereby violent non-state actors target energy infrastructures to air grievances, communicate to governments, impact state economic interests, or capture revenue in the form of hijacking, kidnapping ransoms, theft. And, for politically motivated groups, such as those engaged in insurgencies, attacking industry assets garners media coverage serving as a facilitator for international attention. This research note will introduce EIAD and position its utility within various research areas where the targeting of energy infrastructure, or more broadly energy infrastructure vulnerability, has been addressed, either directly or indirectly. We also provide a snapshot of the initial analysis of the data between 1980-2011, noting specific temporal and spatial trends, and then conclude with a brief discussion on the contribution of EIAD, highlighting future research trajectories. 

  7. Managing Consistency Anomalies in Distributed Integrated Databases with Relaxed ACID Properties

    DEFF Research Database (Denmark)

    Frank, Lars; Ulslev Pedersen, Rasmus

    2014-01-01

    In central databases the consistency of data is normally implemented by using the ACID (Atomicity, Consistency, Isolation and Durability) properties of a DBMS (Data Base Management System). This is not possible if distributed and/or mobile databases are involved and the availability of data also...... distributed consistency property. We will also illustrate how to use the countermeasures against the consistency anomalies in ERP systems integrated with heterogeneous E-commerce systems and the databases of mobile salesman ERP modules. The methods described in this paper may be used in so called CAP...... anomalies for the inconsistencies caused by the missing consistency property in distributed integrated databases with relaxed ACID properties. In this paper, we will describe countermeasures against the consistency anomalies to make it possible to reduce or prevent the consequences of the missing...

  8. Reactor core materials research and integrated material database establishment

    International Nuclear Information System (INIS)

    Mainly two research areas were covered in this project. One is to establish the integrated database of nuclear materials, and the other is to study the behavior of reactor core materials, which are usually under the most severe condition in the operating plants. During the stage I of the project (for three years since 1999) in- and out of reactor properties of stainless steel, the major structural material for the core structures of PWR (Pressurized Water Reactor), were evaluated and specification of nuclear grade material was established. And the damaged core components from domestic power plants, e.g. orifice of CVCS, support pin of CRGT, etc. were investigated and the causes were revealed. To acquire more resistant materials to the nuclear environments, development of the alternative alloys was also conducted. For the integrated DB establishment, a task force team was set up including director of nuclear materials technology team, and projector leaders and relevant members from each project. The DB is now opened in public through the Internet

  9. 77 FR 66622 - Submission for OMB Review; Comment Request: National Database for Autism Research (NDAR) Data...

    Science.gov (United States)

    2012-11-06

    ... Database for Autism Research (NDAR) Data Access Request SUMMARY: Under the provisions of Section 3507(a)(1... control number. Proposed Collection: Title: National Database for Autism Research (NDAR) Data Access... organization or corporations with approved assurance from the DHHS Office of Human Research Protections...

  10. ProtRepeatsDB: a database of amino acid repeats in genomes

    Directory of Open Access Journals (Sweden)

    Chauhan Virander S

    2006-07-01

    Full Text Available Abstract Background Genome wide and cross species comparisons of amino acid repeats is an intriguing problem in biology mainly due to the highly polymorphic nature and diverse functions of amino acid repeats. Innate protein repeats constitute vital functional and structural regions in proteins. Repeats are of great consequence in evolution of proteins, as evident from analysis of repeats in different organisms. In the post genomic era, availability of protein sequences encoded in different genomes provides a unique opportunity to perform large scale comparative studies of amino acid repeats. ProtRepeatsDB http://bioinfo.icgeb.res.in/repeats/ is a relational database of perfect and mismatch repeats, access to which is designed as a resource and collection of tools for detection and cross species comparisons of different types of amino acid repeats. Description ProtRepeatsDB (v1.2 consists of perfect as well as mismatch amino acid repeats in the protein sequences of 141 organisms, the genomes of which are now available. The web interface of ProtRepeatsDB consists of different tools to perform repeat s; based on protein IDs, organism name, repeat sequences, and keywords as in FASTA headers, size, frequency, gene ontology (GO annotation IDs and regular expressions (REGEXP describing repeats. These tools also allow formulation of a variety of simple, complex and logical queries to facilitate mining and large-scale cross-species comparisons of amino acid repeats. In addition to this, the database also contains sequence analysis tools to determine repeats in user input sequences. Conclusion ProtRepeatsDB is a multi-organism database of different types of amino acid repeats present in proteins. It integrates useful tools to perform genome wide queries for rapid screening and identification of amino acid repeats and facilitates comparative and evolutionary studies of the repeats. The database is useful for identification of species or organism specific

  11. COPASAAR – A database for proteomic analysis of single amino acid repeats

    Directory of Open Access Journals (Sweden)

    Dalby Andrew R

    2005-08-01

    Full Text Available Abstract Background Single amino acid repeats make up a significant proportion in all of the proteomes that have currently been determined. They have been shown to be functionally and medically significant, and are associated with cancers and neuro-degenerative diseases such as Huntington's Chorea, where a poly-glutamine repeat is responsible for causing the disease. The COPASAAR database is a new tool to facilitate the rapid analysis of single amino acid repeats at a proteome level. The database aims to simplify the comparison of repeat distributions between proteomes in order to provide a better understanding of their function and evolution. Results A comparative analysis of all proteomes in the database (currently 244 shows that single amino acid repeats account for about 12–14% of the proteome of any given species. They are more common in eukaryotes (14% than in either archaea or bacteria (both 13%. Individual analyses of proteomes show that long single amino acid repeats (6+ residues are much more common in the Eukaryotes and that longer repeats are usually made up of hydrophilic amino acids such as glutamine, glutamic acid, asparagine, aspartic acid and serine. Conclusion COPASAAR is a useful tool for comparative proteomics that provides rapid access to amino acid repeat data that can be readily data-mined. The COPASAAR database can be queried at the kingdom, proteome or individual protein level. As the amount of available proteome data increases this will be increasingly important in order to automate proteome comparison. The insights gained from these studies will give a better insight into the evolution of protein sequence and function.

  12. Database security and encryption technology research and application

    Science.gov (United States)

    Zhu, Li-juan

    2013-03-01

    The main purpose of this paper is to discuss the current database information leakage problem, and discuss the important role played by the message encryption techniques in database security, As well as MD5 encryption technology principle and the use in the field of website or application. This article is divided into introduction, the overview of the MD5 encryption technology, the use of MD5 encryption technology and the final summary. In the field of requirements and application, this paper makes readers more detailed and clearly understood the principle, the importance in database security, and the use of MD5 encryption technology.

  13. Acid Rain Students Do Original Research.

    Science.gov (United States)

    Outdoor Communicator, 1984

    1984-01-01

    At Park Senior High School (Cottage Grove, Minnesota), 46 juniors and seniors planted 384 red pine seedlings in connection with their original research on acid rain, with advice from Dr. Harriet Stubbs, director of the Acid Precipitation Awareness Program (West Saint Paul), which has been developing acid rain teaching materials. (MH)

  14. Comprehensiveness of "Social Work Abstracts" as a Database for Researchers and Practitioners

    Science.gov (United States)

    Shek, Daniel T. L.

    2008-01-01

    Objective: The comprehensiveness of "Social Work Abstracts (SWA)" as a database was examined. Method: The coverage of articles of "Research on Social Work Practice" and "Social Work Research" in "SWA" from 1995 to 2005 was examined. "SWA" was compared with other databases on several dimensions. A case study based on the author's publications was…

  15. Long non-coding RNA Databases in Cardiovascular Research

    Institute of Scientific and Technical Information of China (English)

    Frank Ruhle; Monika Stoll

    2016-01-01

    With the rising interest in the regulatory functions of long non-coding RNAs (lncRNAs) in complex human diseases such as cardiovascular diseases, there is an increasing need in public databases offering comprehensive and integrative data for all aspects of these versatile molecules. Recently, a variety of public data repositories that specialized in lncRNAs have been developed, which make use of huge high-throughput data particularly from next-generation sequencing (NGS) approaches. Here, we provide an overview of current lncRNA databases covering basic and functional annotation, lncRNA expression and regulation, interactions with other biomole-cules, and genomic variants influencing the structure and function of lncRNAs. The prominent lncRNA antisense noncoding RNA in the INK4 locus (ANRIL), which has been unequivocally associated with coronary artery disease through genome-wide association studies (GWAS), serves as an example to demonstrate the features of each individual database.

  16. Research and development of Chinese LCA database and LCA software

    Institute of Scientific and Technical Information of China (English)

    GONG Xianzheng; NIE Zuoren; Wang Zhihong; ZUO Tieyong

    2006-01-01

    This paper detailed introduces the related work for building Chinese National Database, Sinocenter, of materials life cycle assessment (MLCA) and developing the environmental burden dataset of materials.The MLCA database was built in 2004, and the basic framework mainly includes LCA methodology, materials environmental dataset about energy consumption, resource input and environmental emissions.Nowadays, the database contains about fifty-thousand records of the main materials industries, such as cement, iron and steel, nonferrous metal, etc., and also includes the primary LCI data of fossil fuels and electricity grid in China.At the same time, the LCA method localization work is going on, for instance, calculated the resource characterization factors of 42 kinds of metal and 58 sorts of nonmetal, and also obtained some heavy metal impact factors in water.Based on the database, the iron and steel dataset has been developed with the data quality analysis, and some environmental burden data could be queried in our website, www.cnmlca.com, in the future.Lastly, according to the framework of the ISO14040 series standards, the antitype of Chinese LCA evaluation system was developed to support materials and products LCA evaluation in China.

  17. Research of database-based modeling for mining management system

    Institute of Scientific and Technical Information of China (English)

    WU Hai-feng; JIN Zhi-xin; BAI Xi-jun

    2005-01-01

    Put forward the method to construct the simulation model automatically with database-based automatic modeling(DBAM) for mining system. Designed the standard simulation model linked with some open cut Pautomobile dispatch system. Analyzed and finded out the law among them, and designed model maker to realize the automatic programming of the new model program.

  18. Amino Acid Sequence - KOME | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available [ Credits ] BLAST Search Image Search Home About Archive Update History Contact us ...ll_sequence_amino_db.zip File URL: ftp://ftp.biosciencedbc.jp/archive/kome/LATEST...ta.zip File URL: ftp://ftp.biosciencedbc.jp/archive/kome/LATEST/kome_ine_full_sequence_amino_db.fasta.zip Fi...date History of This Database Site Policy | Contact Us Amino Acid Sequence - KOME | LSDB Archive ...

  19. Database of amino acid-nucleotide contacts in the DNA complexes with homeodomain family proteins

    International Nuclear Information System (INIS)

    The analysis of amino acid-nucleotide contacts in interfaces of the protein-DNA complexes, intended to find consistencies in the protein-DNA recognition, is a complex problem that requires analysis of the physicochemical characteristics of these contacts, of the positions of the participating amino acids and nucleotides in the chains of the protein and the DNA, respectively, as well as conservatism of these contacts. Thus, those heterogeneous data should be systematized. For this purpose we have developed a database of amino acid-nucleotide contacts ANTPC (Amino acid Nucleotide Type Position Conservation) following the archetypal example of the proteins in the homeodomain family. We show that it can be used for comparison and classification of interfaces of the protein-DNA complexes

  20. The Beltsville Human Nutrition Research Center's Porcine Immunology and Nutrition Resource Database

    Science.gov (United States)

    Several diverse genomics-based databases have developed to facilitate research with human and rodent models. Current porcine gene databases, however, lack the nutritional and immunological orientation and robust annotation to design effective molecular tools to study relevant pig models. To address ...

  1. Landslide databases for applied landslide impact research: the example of the landslide database for the Federal Republic of Germany

    Science.gov (United States)

    Damm, Bodo; Klose, Martin

    2014-05-01

    This contribution presents an initiative to develop a national landslide database for the Federal Republic of Germany. It highlights structure and contents of the landslide database and outlines its major data sources and the strategy of information retrieval. Furthermore, the contribution exemplifies the database potentials in applied landslide impact research, including statistics of landslide damage, repair, and mitigation. The landslide database offers due to systematic regional data compilation a differentiated data pool of more than 5,000 data sets and over 13,000 single data files. It dates back to 1137 AD and covers landslide sites throughout Germany. In seven main data blocks, the landslide database stores besides information on landslide types, dimensions, and processes, additional data on soil and bedrock properties, geomorphometry, and climatic or other major triggering events. A peculiarity of this landslide database is its storage of data sets on land use effects, damage impacts, hazard mitigation, and landslide costs. Compilation of landslide data is based on a two-tier strategy of data collection. The first step of information retrieval includes systematic web content mining and exploration of online archives of emergency agencies, fire and police departments, and news organizations. Using web and RSS feeds and soon also a focused web crawler, this enables effective nationwide data collection for recent landslides. On the basis of this information, in-depth data mining is performed to deepen and diversify the data pool in key landslide areas. This enables to gather detailed landslide information from, amongst others, agency records, geotechnical reports, climate statistics, maps, and satellite imagery. Landslide data is extracted from these information sources using a mix of methods, including statistical techniques, imagery analysis, and qualitative text interpretation. The landslide database is currently migrated to a spatial database system

  2. Neutron cross-sections database for amino acids and proteins analysis

    International Nuclear Information System (INIS)

    Biological materials may be studied using neutrons as an unconventional tool of analysis. Dynamics and structures data can be obtained for amino acids, protein and others cellular components by neutron cross sections determinations especially for applications in nuclear purity and conformation analysis. The instrument used for this is the crystal spectrometer of the Instituto de Engenharia Nuclear (IEN-CNEN-RJ), the only one in Latin America that uses neutrons for this type of analyzes and it is installed in one of the reactor Argonauta irradiation channels. The experimentally values obtained are compared with calculated values using literature data with a rigorous analysis of the chemical composition, conformation and molecular structure analysis of the materials. A neutron cross-section database was constructed to assist in determining molecular dynamic, structure and formulae of biological materials. The database contains neutron cross-sections values of all amino acids, chemical elements, molecular groups, auxiliary radicals, as well as values of constants and parameters necessary for the analysis. An unprecedented analytical procedure was developed using the neutron cross section parceling and grouping method for data manipulation. This database is a result of measurements obtained from twenty amino acids that were provided by different manufactories and are used in oral administration in hospital individuals for nutritional applications. It was also constructed a small data file of compounds with different molecular groups including carbon, nitrogen, sulfur and oxygen, all linked to hydrogen atoms. A review of global and national scene in the acquisition of neutron cross sections data, the formation of libraries and the application of neutrons for analyzing biological materials is presented. This database has further application in protein analysis and the neutron cross-section from the insulin was estimated. (author)

  3. Neutron cross-sections database for amino acids and proteins analysis

    Energy Technology Data Exchange (ETDEWEB)

    Voi, Dante L.; Ferreira, Francisco de O.; Nunes, Rogerio Chaffin, E-mail: dante@ien.gov.br, E-mail: fferreira@ien.gov.br, E-mail: Chaffin@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Rocha, Helio F. da, E-mail: hrocha@gbl.com.br [Universidade Federal do Rio de Janeiro (IPPMG/UFRJ), Rio de Janeiro, RJ (Brazil). Instituto de Pediatria

    2015-07-01

    Biological materials may be studied using neutrons as an unconventional tool of analysis. Dynamics and structures data can be obtained for amino acids, protein and others cellular components by neutron cross sections determinations especially for applications in nuclear purity and conformation analysis. The instrument used for this is the crystal spectrometer of the Instituto de Engenharia Nuclear (IEN-CNEN-RJ), the only one in Latin America that uses neutrons for this type of analyzes and it is installed in one of the reactor Argonauta irradiation channels. The experimentally values obtained are compared with calculated values using literature data with a rigorous analysis of the chemical composition, conformation and molecular structure analysis of the materials. A neutron cross-section database was constructed to assist in determining molecular dynamic, structure and formulae of biological materials. The database contains neutron cross-sections values of all amino acids, chemical elements, molecular groups, auxiliary radicals, as well as values of constants and parameters necessary for the analysis. An unprecedented analytical procedure was developed using the neutron cross section parceling and grouping method for data manipulation. This database is a result of measurements obtained from twenty amino acids that were provided by different manufactories and are used in oral administration in hospital individuals for nutritional applications. It was also constructed a small data file of compounds with different molecular groups including carbon, nitrogen, sulfur and oxygen, all linked to hydrogen atoms. A review of global and national scene in the acquisition of neutron cross sections data, the formation of libraries and the application of neutrons for analyzing biological materials is presented. This database has further application in protein analysis and the neutron cross-section from the insulin was estimated. (author)

  4. BIGNASim: a NoSQL database structure and analysis portal for nucleic acids simulation data.

    Science.gov (United States)

    Hospital, Adam; Andrio, Pau; Cugnasco, Cesare; Codo, Laia; Becerra, Yolanda; Dans, Pablo D; Battistini, Federica; Torres, Jordi; Goñi, Ramón; Orozco, Modesto; Gelpí, Josep Ll

    2016-01-01

    Molecular dynamics simulation (MD) is, just behind genomics, the bioinformatics tool that generates the largest amounts of data, and that is using the largest amount of CPU time in supercomputing centres. MD trajectories are obtained after months of calculations, analysed in situ, and in practice forgotten. Several projects to generate stable trajectory databases have been developed for proteins, but no equivalence exists in the nucleic acids world. We present here a novel database system to store MD trajectories and analyses of nucleic acids. The initial data set available consists mainly of the benchmark of the new molecular dynamics force-field, parmBSC1. It contains 156 simulations, with over 120 μs of total simulation time. A deposition protocol is available to accept the submission of new trajectory data. The database is based on the combination of two NoSQL engines, Cassandra for storing trajectories and MongoDB to store analysis results and simulation metadata. The analyses available include backbone geometries, helical analysis, NMR observables and a variety of mechanical analyses. Individual trajectories and combined meta-trajectories can be downloaded from the portal. The system is accessible through http://mmb.irbbarcelona.org/BIGNASim/. Supplementary Material is also available on-line at http://mmb.irbbarcelona.org/BIGNASim/SuppMaterial/. PMID:26612862

  5. A Temporal Abstraction-based Extract, Transform and Load Process for Creating Registry Databases for Research.

    Science.gov (United States)

    Post, Andrew; Kurc, Tahsin; Overcash, Marc; Cantrell, Dedra; Morris, Tim; Eckerson, Kristi; Tsui, Circe; Willey, Terry; Quyyumi, Arshed; Eapen, Danny; Umpierrez, Guillermo; Ziemer, David; Saltz, Joel

    2011-01-01

    In the CTSA era there is great interest in aggregating and comparing populations across institutions. These sites likely represent data differently in their clinical data warehouses and other databases. Clinical data warehouses frequently are structured in a generalized way that supports many constituencies. For research, there is a need to transform these heterogeneous data into a shared representation, and to perform categorization and interpretation to optimize the data representation for investigators. We are addressing this need by extending an existing temporal abstraction-based clinical database query system, PROTEMPA. The extended system allows specifying data types of interest in federated databases, extracting the data into a shared representation, transforming it through categorization and interpretation, and loading it into a registry database that can be refreshed. Such a registry's access control, data representation and query tools can be tailored to the needs of research while keeping local databases as the source of truth. PMID:22211179

  6. A Relational Database of WHO Mortality Data Prepared to Facilitate Global Mortality Research

    Directory of Open Access Journals (Sweden)

    Albert de Roos

    2015-09-01

    Full Text Available Detailed world mortality data such as collected by the World Health Organization gives a wealth of information about causes of death worldwide over a time span of 60 year. However, the raw mortality data in text format as provided by the WHO is not directly suitable for systematic research and data mining. In this Data Paper, a relational database is presented that is created from the raw WHO mortality data set and includes mortality rates, an ICD-code table and country reference data. This enriched database, as a corpus of global mortality data, can be readily imported in relational databases but can also function as the data source for other types of databases. The use of this database can therefore greatly facilitate global epidemiological research that may provide new clues to genetic or environmental factors in the origins of diseases.

  7. Nigeria Anopheles vector database: an overview of 100 years' research.

    Directory of Open Access Journals (Sweden)

    Patricia Nkem Okorie

    Full Text Available Anopheles mosquitoes are important vectors of malaria and lymphatic filariasis (LF, which are major public health diseases in Nigeria. Malaria is caused by infection with a protozoan parasite of the genus Plasmodium and LF by the parasitic worm Wuchereria bancrofti. Updating our knowledge of the Anopheles species is vital in planning and implementing evidence based vector control programs. To present a comprehensive report on the spatial distribution and composition of these vectors, all published data available were collated into a database. Details recorded for each source were the locality, latitude/longitude, time/period of study, species, abundance, sampling/collection methods, morphological and molecular species identification methods, insecticide resistance status, including evidence of the kdr allele, and P. falciparum sporozoite rate and W. bancrofti microfilaria prevalence. This collation resulted in a total of 110 publications, encompassing 484,747 Anopheles mosquitoes in 632 spatially unique descriptions at 142 georeferenced locations being identified across Nigeria from 1900 to 2010. Overall, the highest number of vector species reported included An. gambiae complex (65.2%, An. funestus complex (17.3%, An. gambiae s.s. (6.5%. An. arabiensis (5.0% and An. funestus s.s. (2.5%, with the molecular forms An. gambiae M and S identified at 120 locations. A variety of sampling/collection and species identification methods were used with an increase in molecular techniques in recent decades. Insecticide resistance to pyrethroids and organochlorines was found in the main Anopheles species across 45 locations. Presence of P. falciparum and W. bancrofti varied between species with the highest sporozoite rates found in An. gambiae s.s, An. funestus s.s. and An. moucheti, and the highest microfilaria prevalence in An. gambiae s.l., An. arabiensis, and An. gambiae s.s. This comprehensive geo-referenced database provides an essential baseline on

  8. The Danish Integrated Database for Labor Market Research: Towards Demystification for the English Speaking Audience

    OpenAIRE

    Bram Timmermans

    2010-01-01

    An increasing number of studies, in a wide range of disciplines, make use of so-called linked employer-employee databases. These detailed databases are only available in a limited number of countries. Denmark is one of the countries that makes this data available to researchers that are connected to a Danish research institute. Due to the sensitivity of the data, access is only granted after a thorough screening process and under strict conditions. Nevertheless, there is an international inte...

  9. Importance of databases of nucleic acids for bioinformatic analysis focused to genomics

    Science.gov (United States)

    Jimenez-Gutierrez, L. R.; Barrios-Hernández, C. J.; Pedraza-Ferreira, G. R.; Vera-Cala, L.; Martinez-Perez, F.

    2016-08-01

    Recently, bioinformatics has become a new field of science, indispensable in the analysis of millions of nucleic acids sequences, which are currently deposited in international databases (public or private); these databases contain information of genes, RNA, ORF, proteins, intergenic regions, including entire genomes from some species. The analysis of this information requires computer programs; which were renewed in the use of new mathematical methods, and the introduction of the use of artificial intelligence. In addition to the constant creation of supercomputing units trained to withstand the heavy workload of sequence analysis. However, it is still necessary the innovation on platforms that allow genomic analyses, faster and more effectively, with a technological understanding of all biological processes.

  10. Knowledge map of artemisinin research in SCI and Medline database

    OpenAIRE

    Qiang Yao , Jing Chen , Peng-Hui Lyu , Shi-Jing Zhang , Fei-Cheng Ma & Jian-Guo Fang

    2012-01-01

    Background & objectives: Artemisinin was first extracted from the herb Artemisia annua which has been used formany centuries in Chinese traditional medicine as a treatment for fever and malaria. It has been given the 2011Lasker-DeBakey clinical medical research award. In this paper, knowledge map of artemisinin research wasdrawn to provide some information for global researchers interested in artemisinin and its relevant references.Methods: In this work, bibliometric analysis and knowledge vi...

  11. How can the research potential of the clinical quality databases be maximized? The Danish experience.

    Science.gov (United States)

    Nørgaard, M; Johnsen, S P

    2016-02-01

    In Denmark, the need for monitoring of clinical quality and patient safety with feedback to the clinical, administrative and political systems has resulted in the establishment of a network of more than 60 publicly financed nationwide clinical quality databases. Although primarily devoted to monitoring and improving quality of care, the potential of these databases as data sources in clinical research is increasingly being recognized. In this review, we describe these databases focusing on their use as data sources for clinical research, including their strengths and weaknesses as well as future concerns and opportunities. The research potential of the clinical quality databases is substantial but has so far only been explored to a limited extent. Efforts related to technical, legal and financial challenges are needed in order to take full advantage of this potential. PMID:26785952

  12. Research in Mobile Database Query Optimization and Processing

    Directory of Open Access Journals (Sweden)

    Agustinus Borgy Waluyo

    2005-01-01

    Full Text Available The emergence of mobile computing provides the ability to access information at any time and place. However, as mobile computing environments have inherent factors like power, storage, asymmetric communication cost, and bandwidth limitations, efficient query processing and minimum query response time are definitely of great interest. This survey groups a variety of query optimization and processing mechanisms in mobile databases into two main categories, namely: (i query processing strategy, and (ii caching management strategy. Query processing includes both pull and push operations (broadcast mechanisms. We further classify push operation into on-demand broadcast and periodic broadcast. Push operation (on-demand broadcast relates to designing techniques that enable the server to accommodate multiple requests so that the request can be processed efficiently. Push operation (periodic broadcast corresponds to data dissemination strategies. In this scheme, several techniques to improve the query performance by broadcasting data to a population of mobile users are described. A caching management strategy defines a number of methods for maintaining cached data items in clients' local storage. This strategy considers critical caching issues such as caching granularity, caching coherence strategy and caching replacement policy. Finally, this survey concludes with several open issues relating to mobile query optimization and processing strategy.

  13. About the database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Until now,Meteorological and Environmental Research [ISSN: 2152 - 3940] has been included by CAS and CABI from 2010.CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive

  14. About the database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Meteorological and Environmental Research [ISSN: 2152 -3940]has been included by CAS and CABI since 2010. CAS is a division of the American Chemical Society established in 1907,and is the most authoritative and comprehensive

  15. About the database of Meteorological and Environmental Research

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Until now, Meteorological and Environmental Research [ISSN:2152-3940] has been included by CAS and CABI from 2010. CAS is a division of the American Chemical Society established in 1907, and is the most authoritative and comprehensive source for chemical information. It is praised as the key of world literature treasury of Chemistry and Chemical. CAS monitors, indexes, and abstracts the world's chemistry-related literature and patents, updates this information daily, and makes it accessible through state...

  16. The Pitfalls of Cyberspace and Electronic Database Research--Who Sells What to Whom for Which Audience?

    Science.gov (United States)

    Willey, Susan

    2000-01-01

    Raises questions about the validity and reliability of doing research online via the proliferation of academic databases. Finds different versions of the Lexis-Nexis database have differing search capabilities. Argues that dependence on database research findings means dependence on decisions made by a few people who design search engines and…

  17. Acid mine drainage. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The bibliography contains citations concerning laboratory and field analyses of acid mine drainage. Topics include site investigations and characterization, remediation and monitoring programs, contaminant treatment research, and control and abatement studies. Chemical analyses of affected areas, and evaluation of terrestrial and aquatic ecosystem responses to acid drainage are also discussed. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  18. Large-scale spatial population databases in infectious disease research.

    Science.gov (United States)

    Linard, Catherine; Tatem, Andrew J

    2012-01-01

    Modelling studies on the spatial distribution and spread of infectious diseases are becoming increasingly detailed and sophisticated, with global risk mapping and epidemic modelling studies now popular. Yet, in deriving populations at risk of disease estimates, these spatial models must rely on existing global and regional datasets on population distribution, which are often based on outdated and coarse resolution data. Moreover, a variety of different methods have been used to model population distribution at large spatial scales. In this review we describe the main global gridded population datasets that are freely available for health researchers and compare their construction methods, and highlight the uncertainties inherent in these population datasets. We review their application in past studies on disease risk and dynamics, and discuss how the choice of dataset can affect results. Moreover, we highlight how the lack of contemporary, detailed and reliable data on human population distribution in low income countries is proving a barrier to obtaining accurate large-scale estimates of population at risk and constructing reliable models of disease spread, and suggest research directions required to further reduce these barriers. PMID:22433126

  19. Large-scale spatial population databases in infectious disease research

    Directory of Open Access Journals (Sweden)

    Linard Catherine

    2012-03-01

    Full Text Available Abstract Modelling studies on the spatial distribution and spread of infectious diseases are becoming increasingly detailed and sophisticated, with global risk mapping and epidemic modelling studies now popular. Yet, in deriving populations at risk of disease estimates, these spatial models must rely on existing global and regional datasets on population distribution, which are often based on outdated and coarse resolution data. Moreover, a variety of different methods have been used to model population distribution at large spatial scales. In this review we describe the main global gridded population datasets that are freely available for health researchers and compare their construction methods, and highlight the uncertainties inherent in these population datasets. We review their application in past studies on disease risk and dynamics, and discuss how the choice of dataset can affect results. Moreover, we highlight how the lack of contemporary, detailed and reliable data on human population distribution in low income countries is proving a barrier to obtaining accurate large-scale estimates of population at risk and constructing reliable models of disease spread, and suggest research directions required to further reduce these barriers.

  20. Raman database of amino acids solutions: A critical study of Extended Multiplicative Signal Correction

    KAUST Repository

    Candeloro, Patrizio

    2013-01-01

    The Raman spectra of biological materials always exhibit complex profiles, constituting several peaks and/or bands which arise due to the large variety of biomolecules. The extraction of quantitative information from these spectra is not a trivial task. While qualitative information can be retrieved from the changes in peaks frequencies or from the appearance/disappearance of some peaks, quantitative analysis requires an examination of peak intensities. Unfortunately in biological samples it is not easy to identify a reference peak for normalizing intensities, and this makes it very difficult to study the peak intensities. In the last decades a more refined mathematical tool, the extended multiplicative signal correction (EMSC), has been proposed for treating infrared spectra, which is also capable of providing quantitative information. From the mathematical and physical point of view, EMSC can also be applied to Raman spectra, as recently proposed. In this work the reliability of the EMSC procedure is tested by application to a well defined biological system: the 20 standard amino acids and their combination in peptides. The first step is the collection of a Raman database of these 20 amino acids, and subsequently EMSC processing is applied to retrieve quantitative information from amino acids mixtures and peptides. A critical review of the results is presented, showing that EMSC has to be carefully handled for complex biological systems. © 2013 The Royal Society of Chemistry.

  1. Voluntary fortification with folic acid in Spain: An updated food composition database.

    Science.gov (United States)

    Samaniego-Vaesken, M L; Alonso-Aperte, E; Varela-Moreiras, G

    2016-02-15

    Folic acid (FA) is a key vitamin in the prevention of many diseases including neural tube defects. In Spain, only voluntary FA food fortification is allowed and there is a lack of compositional data to assess the contribution of these products to population's dietary folate intakes. Since 2007, our group has been compiling and updating a FA fortified food composition database. FA levels were obtained from retailers in Madrid and information provided by manufacturers. FA was also quantified by an affinity chromatography-HPLC method. In the present study we recorded 375 products. Our results show a high variability in the declared FA levels amongst different products, and food groups, which is also dependant on the commercial brand. FA overages are commonly added by manufacturers to some fortified products. FA content label claims are missing in 64% of products. This database is a useful tool to manage FA fortified foods data but it is necessary to continuously update it for the sound evaluation and monitoring of population's FA dietary intakes.

  2. Moving to Google Cloud: Renovation of Global Borehole Temperature Database for Climate Research

    Science.gov (United States)

    Xiong, Y.; Huang, S.

    2013-12-01

    Borehole temperature comprises an independent archive of information on climate change which is complementary to the instrumental and other proxy climate records. With support from the international geothermal community, a global database of borehole temperatures has been constructed for the specific purpose of the study on climate change. Although this database has become an important data source in climate research, there are certain limitations partially because the framework of the existing borehole temperature database was hand-coded some twenty years ago. A database renovation work is now underway to take the advantages of the contemporary online database technologies. The major intended improvements include 1) dynamically linking a borehole site to Google Earth to allow for inspection of site specific geographical information; 2) dynamically linking an original key reference of a given borehole site to Google Scholar to allow for a complete list of related publications; and 3) enabling site selection and data download based on country, coordinate range, and contributor. There appears to be a good match between the enhancement requirements for this database and the functionalities of the newly released Google Fusion Tables application. Google Fusion Tables is a cloud-based service for data management, integration, and visualization. This experimental application can consolidate related online resources such as Google Earth, Google Scholar, and Google Drive for sharing and enriching an online database. It is user friendly, allowing users to apply filters and to further explore the internet for additional information regarding the selected data. The users also have ways to map, to chart, and to calculate on the selected data, and to download just the subset needed. The figure below is a snapshot of the database currently under Google Fusion Tables renovation. We invite contribution and feedback from the geothermal and climate research community to make the

  3. Development of a pseudo/anonymised primary care research database: Proof-of-concept study.

    Science.gov (United States)

    MacRury, Sandra; Finlayson, Jim; Hussey-Wilson, Susan; Holden, Samantha

    2016-06-01

    General practice records present a comprehensive source of data that could form a variety of anonymised or pseudonymised research databases to aid identification of potential research participants regardless of location. A proof-of-concept study was undertaken to extract data from general practice systems in 15 practices across the region to form pseudo and anonymised research data sets. Two feasibility studies and a disease surveillance study compared numbers of potential study participants and accuracy of disease prevalence, respectively. There was a marked reduction in screening time and increase in numbers of potential study participants identified with the research repository compared with conventional methods. Accurate disease prevalence was established and enhanced with the addition of selective text mining. This study confirms the potential for development of national anonymised research database from general practice records in addition to improving data collection for local or national audits and epidemiological projects. PMID:24935212

  4. Development of a pseudo/anonymised primary care research database: Proof-of-concept study.

    Science.gov (United States)

    MacRury, Sandra; Finlayson, Jim; Hussey-Wilson, Susan; Holden, Samantha

    2016-06-01

    General practice records present a comprehensive source of data that could form a variety of anonymised or pseudonymised research databases to aid identification of potential research participants regardless of location. A proof-of-concept study was undertaken to extract data from general practice systems in 15 practices across the region to form pseudo and anonymised research data sets. Two feasibility studies and a disease surveillance study compared numbers of potential study participants and accuracy of disease prevalence, respectively. There was a marked reduction in screening time and increase in numbers of potential study participants identified with the research repository compared with conventional methods. Accurate disease prevalence was established and enhanced with the addition of selective text mining. This study confirms the potential for development of national anonymised research database from general practice records in addition to improving data collection for local or national audits and epidemiological projects.

  5. Development of a computational database for probabilistic safety assessment of nuclear research reactors

    Energy Technology Data Exchange (ETDEWEB)

    Macedo, Vagner S.; Oliveira, Patricia S. Pagetti de; Andrade, Delvonei Alves de, E-mail: vagner.macedo@usp.br, E-mail: patricia@ipen.br, E-mail: delvonei@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    The objective of this work is to describe the database being developed at IPEN - CNEN / SP for application in the Probabilistic Safety Assessment of nuclear research reactors. The database can be accessed by means of a computational program installed in the corporate computer network, named IPEN Intranet, and this access will be allowed only to professionals previously registered. Data updating, editing and searching tasks will be controlled by a system administrator according to IPEN Intranet security rules. The logical model and the physical structure of the database can be represented by an Entity Relationship Model, which is based on the operational routines performed by IPEN - CNEN / SP users. The web application designed for the management of the database is named PSADB. It is being developed with MySQL database software and PHP programming language is being used. Data stored in this database are divided into modules that refer to technical specifications, operating history, maintenance history and failure events associated with the main components of the nuclear facilities. (author)

  6. YPED:An Integrated Bioinformatics Suite and Database for Mass Spectrometry-based Proteomics Research

    Institute of Scientific and Technical Information of China (English)

    Christopher M. Colangelo; Can Bruce; Angus C. Nairn; Jesse Rinehart; Perry L. Miller; Kenneth R. Williams; Mark Shifman; Kei-Hoi Cheung; Kathryn L. Stone; Nicholas J. Carriero; Erol E. Gulcicek; TuKiet T. Lam; Terence Wu; Robert D. Bjornson

    2015-01-01

    We report a significantly-enhanced bioinformatics suite and database for proteomics research called Yale Protein Expression Database (YPED) that is used by investigators at more than 300 institutions worldwide. YPED meets the data management, archival, and analysis needs of a high-throughput mass spectrometry-based proteomics research ranging from a single laboratory, group of laboratories within and beyond an institution, to the entire proteomics com-munity. The current version is a significant improvement over the first version in that it contains new modules for liquid chromatography–tandem mass spectrometry (LC–MS/MS) database search results, label and label-free quantitative proteomic analysis, and several scoring outputs for phosphopeptide site localization. In addition, we have added both peptide and protein comparative analysis tools to enable pairwise analysis of distinct peptides/proteins in each sample and of overlapping peptides/proteins between all samples in multiple datasets. We have also implemented a targeted proteomics module for automated multiple reaction monitoring (MRM)/selective reaction monitoring (SRM) assay development. We have linked YPED’s database search results and both label-based and label-free fold-change analysis to the Skyline Panorama repository for online spectra visualization. In addition, we have built enhanced functionality to curate peptide identifications into an MS/MS peptide spectral library for all of our protein database search identification results.

  7. Data-Based Decision Making at the Policy, Research, and Practice Levels

    NARCIS (Netherlands)

    Schildkamp, Kim; Ebbeler, Johanna

    2015-01-01

    Data-based decision making (DBDM) can lead to school improvement. However, schools struggle with the implementation of DBDM. In this symposium, we will discuss research and the implementation of DBDM at the national and regional policy level and the classroom level. We will discuss policy issues aro

  8. Quality standards for real-world research. Focus on observational database studies of comparative effectiveness.

    Science.gov (United States)

    Roche, Nicolas; Reddel, Helen; Martin, Richard; Brusselle, Guy; Papi, Alberto; Thomas, Mike; Postma, Dirjke; Thomas, Vicky; Rand, Cynthia; Chisholm, Alison; Price, David

    2014-02-01

    Real-world research can use observational or clinical trial designs, in both cases putting emphasis on high external validity, to complement the classical efficacy randomized controlled trials (RCTs) with high internal validity. Real-world research is made necessary by the variety of factors that can play an important a role in modulating effectiveness in real life but are often tightly controlled in RCTs, such as comorbidities and concomitant treatments, adherence, inhalation technique, access to care, strength of doctor-caregiver communication, and socio-economic and other organizational factors. Real-world studies belong to two main categories: pragmatic trials and observational studies, which can be prospective or retrospective. Focusing on comparative database observational studies, the process aimed at ensuring high-quality research can be divided into three parts: preparation of research, analyses and reporting, and discussion of results. Key points include a priori planning of data collection and analyses, identification of appropriate database(s), proper outcomes definition, study registration with commitment to publish, bias minimization through matching and adjustment processes accounting for potential confounders, and sensitivity analyses testing the robustness of results. When these conditions are met, observational database studies can reach a sufficient level of evidence to help create guidelines (i.e., clinical and regulatory decision-making).

  9. Current trends and new challenges of databases and web applications for systems driven biological research

    Directory of Open Access Journals (Sweden)

    Pradeep Kumar eSreenivasaiah

    2010-12-01

    Full Text Available Dynamic and rapidly evolving nature of systems driven research imposes special requirements on the technology, approach, design and architecture of computational infrastructure including database and web application. Several solutions have been proposed to meet the expectations and novel methods have been developed to address the persisting problems of data integration. It is important for researchers to understand different technologies and approaches. Having familiarized with the pros and cons of the existing technologies, researchers can exploit its capabilities to the maximum potential for integrating data. In this review we discuss the architecture, design and key technologies underlying some of the prominent databases (DBs and web applications. We will mention their roles in integration of biological data and investigate some of the emerging design concepts and computational technologies that are likely to have a key role in the future of systems driven biomedical research.

  10. Privacy protection and public goods: building a genetic database for health research in Newfoundland and Labrador

    OpenAIRE

    Kosseim, Patricia; Pullman, Daryl; Perrot-Daley, Astrid; Hodgkinson, Kathy; Street, Catherine; Rahman, Proton

    2013-01-01

    Objective To provide a legal and ethical analysis of some of the implementation challenges faced by the Population Therapeutics Research Group (PTRG) at Memorial University (Canada), in using genealogical information offered by individuals for its genetics research database. Materials and methods This paper describes the unique historical and genetic characteristics of the Newfoundland and Labrador founder population, which gave rise to the opportunity for PTRG to build the Newfoundland Genea...

  11. PeDaB - the personal dosimetry database at the research centre Juelich

    International Nuclear Information System (INIS)

    In May, 1997 the mainframe based registration, processing and archiving of personal monitoring data at the research centre Juelich (FZJ) was transferred to a client server system. A complex database application was developed. The client user interface is a Windows based Microsoft ACCESS application which is connected to an ORACLE database via ODBC and TCP/IP. The conversion covered all areas of personal dosimetry including internal and external exposition as well as administrative areas. A higher degree of flexibility, data security and integrity was achieved. (orig.)

  12. GDR (Genome Database for Rosaceae: integrated web resources for Rosaceae genomics and genetics research

    Directory of Open Access Journals (Sweden)

    Ficklin Stephen

    2004-09-01

    Full Text Available Abstract Background Peach is being developed as a model organism for Rosaceae, an economically important family that includes fruits and ornamental plants such as apple, pear, strawberry, cherry, almond and rose. The genomics and genetics data of peach can play a significant role in the gene discovery and the genetic understanding of related species. The effective utilization of these peach resources, however, requires the development of an integrated and centralized database with associated analysis tools. Description The Genome Database for Rosaceae (GDR is a curated and integrated web-based relational database. GDR contains comprehensive data of the genetically anchored peach physical map, an annotated peach EST database, Rosaceae maps and markers and all publicly available Rosaceae sequences. Annotations of ESTs include contig assembly, putative function, simple sequence repeats, and anchored position to the peach physical map where applicable. Our integrated map viewer provides graphical interface to the genetic, transcriptome and physical mapping information. ESTs, BACs and markers can be queried by various categories and the search result sites are linked to the integrated map viewer or to the WebFPC physical map sites. In addition to browsing and querying the database, users can compare their sequences with the annotated GDR sequences via a dedicated sequence similarity server running either the BLAST or FASTA algorithm. To demonstrate the utility of the integrated and fully annotated database and analysis tools, we describe a case study where we anchored Rosaceae sequences to the peach physical and genetic map by sequence similarity. Conclusions The GDR has been initiated to meet the major deficiency in Rosaceae genomics and genetics research, namely a centralized web database and bioinformatics tools for data storage, analysis and exchange. GDR can be accessed at http://www.genome.clemson.edu/gdr/.

  13. A guide for medical information searches of bibliographic databases - psychiatric research as an example.

    Science.gov (United States)

    Löhönen, Johanna; Isohanni, Matti; Nieminen, Pentti; Miettunen, Jouko

    2009-09-01

    Information overload, demanding work with strict time limits, and the extensive number of medical bibliographic databases and other research sources all underline the importance of being able to search for up-to-date information effectively. Medical journals play a key role in providing access to the latest information in medicine and health and bibliographic databases play an important role in accessing them. This paper sheds light on the role of the information search process and discusses how to approach key medical bibliographic databases and information sources, using the field of psychiatry as an example. Because of an increasing amount of information, the constant renewal within the discipline and a variety of services available, those seeking information must precisely define what kind of information they are looking for and from which sources the information needed may be found.

  14. DOG-SPOT database for comprehensive management of dog genetic research data

    Directory of Open Access Journals (Sweden)

    Sutter Nathan B

    2010-12-01

    Full Text Available Abstract Research laboratories studying the genetics of companion animals have no database tools specifically designed to aid in the management of the many kinds of data that are generated, stored and analyzed. We have developed a relational database, "DOG-SPOT," to provide such a tool. Implemented in MS-Access, the database is easy to extend or customize to suit a lab's particular needs. With DOG-SPOT a lab can manage data relating to dogs, breeds, samples, biomaterials, phenotypes, owners, communications, amplicons, sequences, markers, genotypes and personnel. Such an integrated data structure helps ensure high quality data entry and makes it easy to track physical stocks of biomaterials and oligonucleotides.

  15. Respiratory infections research in afghanistan: bibliometric analysis with the database pubmed

    International Nuclear Information System (INIS)

    Infectious diseases research in a low-income country like Afghanistan is important. Methods: In this study an internet-based database Pubmed was used for bibliometric analysis of infectious diseases research activity. Research publications entries in PubMed were analysed according to number of publications, topic, publication type, and country of investigators. Results: Between 2002-2011, 226 (77.7%) publications with the following research topics were identified: respiratory infections 3 (1.3%); parasites 8 (3.5%); diarrhoea 10 (4.4%); tuberculosis 10 (4.4%); human immunodeficiency virus (HIV) 11(4.9%); multi-drug resistant bacteria (MDR) 18(8.0%); polio 31(13.7%); leishmania 31(13.7%); malaria 46(20.4%). From 2002-2011, 11 (4.9%) publications were basic science laboratory-based research studies. Between 2002-2011, 8 (3.5%) publications from Afghan institutions were identified. Conclusion: In conclusion, the internet-based database Pubmed can be consulted to collect data for guidance of infectious diseases research activity of low-income countries. The presented data suggest that infectious diseases research in Afghanistan is limited for respiratory infections research, has few studies conducted by Afghan institutions, and limited laboratory-based research contributions. (author)

  16. Creating a sampling frame for population-based veteran research: Representativeness and overlap of VA and Department of Defense databases

    Directory of Open Access Journals (Sweden)

    Donna L. Washington, MD, MPH

    2010-10-01

    Full Text Available Most veteran research is conducted in Department of Veterans Affairs (VA healthcare settings, although most veterans obtain healthcare outside the VA. Our objective was to determine the adequacy and relative contributions of Veterans Health Administration (VHA, Veterans Benefits Administration (VBA, and Department of Defense (DOD administrative databases for representing the U.S. veteran population, using as an example the creation of a sampling frame for the National Survey of Women Veterans. In 2008, we merged the VHA, VBA, and DOD databases. We identified the number of unique records both overall and from each database. The combined databases yielded 925,946 unique records, representing 51% of the 1,802,000 U.S. women veteran population. The DOD database included 30% of the population (with 8% overlap with other databases. The VHA enrollment database contributed an additional 20% unique women veterans (with 6% overlap with VBA databases. VBA databases contributed an additional 2% unique women veterans (beyond 10% overlap with other databases. Use of VBA and DOD databases substantially expands access to the population of veterans beyond those in VHA databases, regardless of VA use. Adoption of these additional databases would enhance the value and generalizability of a wide range of studies of both male and female veterans.

  17. A middle layer solution to support ACID properties for NoSQL databases

    Directory of Open Access Journals (Sweden)

    Ayman E. Lotfy

    2016-01-01

    Full Text Available The main objective of this paper is to keep the strengths of RDBMSs as consistency and ACID properties and at the same time providing the benefits that inspired the NoSQL movement through a middle layer. The proposed middle layer uses a four phase commit protocol to ensure: the use of recent data, the use of the Pessimistic technique to forbid others dealing with data while it is used and the data updates residing in many locations to avoid the loss of data and disappointment. This mechanism is required, especially in distributed database application NoSQL based environment, because allowing conflicting transactions to continue not only wastes constrained computing power and decreases bandwidth, but also exacerbates conflicts. The middle layer keeps tracking all running transactions and manages with other layers the execution of concurrent transactions. This solution will help increase both of the scalability, and throughput. Finally, the experimental results show that the throughput of the system improves on increasing the number of middle layers in scenarios and the amount of updates to read in a transaction increases. Also the data are consistent with executing many transactions related to each other through updating the same data. The scalability and availability of the system is not affected while ensuring strict consistency.

  18. Insight: An ontology-based integrated database and analysis platform for epilepsy self-management research.

    Science.gov (United States)

    Sahoo, Satya S; Ramesh, Priya; Welter, Elisabeth; Bukach, Ashley; Valdez, Joshua; Tatsuoka, Curtis; Bamps, Yvan; Stoll, Shelley; Jobst, Barbara C; Sajatovic, Martha

    2016-10-01

    We present Insight as an integrated database and analysis platform for epilepsy self-management research as part of the national Managing Epilepsy Well Network. Insight is the only available informatics platform for accessing and analyzing integrated data from multiple epilepsy self-management research studies with several new data management features and user-friendly functionalities. The features of Insight include, (1) use of Common Data Elements defined by members of the research community and an epilepsy domain ontology for data integration and querying, (2) visualization tools to support real time exploration of data distribution across research studies, and (3) an interactive visual query interface for provenance-enabled research cohort identification. The Insight platform contains data from five completed epilepsy self-management research studies covering various categories of data, including depression, quality of life, seizure frequency, and socioeconomic information. The data represents over 400 participants with 7552 data points. The Insight data exploration and cohort identification query interface has been developed using Ruby on Rails Web technology and open source Web Ontology Language Application Programming Interface to support ontology-based reasoning. We have developed an efficient ontology management module that automatically updates the ontology mappings each time a new version of the Epilepsy and Seizure Ontology is released. The Insight platform features a Role-based Access Control module to authenticate and effectively manage user access to different research studies. User access to Insight is managed by the Managing Epilepsy Well Network database steering committee consisting of representatives of all current collaborating centers of the Managing Epilepsy Well Network. New research studies are being continuously added to the Insight database and the size as well as the unique coverage of the dataset allows investigators to conduct

  19. Insight: An ontology-based integrated database and analysis platform for epilepsy self-management research.

    Science.gov (United States)

    Sahoo, Satya S; Ramesh, Priya; Welter, Elisabeth; Bukach, Ashley; Valdez, Joshua; Tatsuoka, Curtis; Bamps, Yvan; Stoll, Shelley; Jobst, Barbara C; Sajatovic, Martha

    2016-10-01

    We present Insight as an integrated database and analysis platform for epilepsy self-management research as part of the national Managing Epilepsy Well Network. Insight is the only available informatics platform for accessing and analyzing integrated data from multiple epilepsy self-management research studies with several new data management features and user-friendly functionalities. The features of Insight include, (1) use of Common Data Elements defined by members of the research community and an epilepsy domain ontology for data integration and querying, (2) visualization tools to support real time exploration of data distribution across research studies, and (3) an interactive visual query interface for provenance-enabled research cohort identification. The Insight platform contains data from five completed epilepsy self-management research studies covering various categories of data, including depression, quality of life, seizure frequency, and socioeconomic information. The data represents over 400 participants with 7552 data points. The Insight data exploration and cohort identification query interface has been developed using Ruby on Rails Web technology and open source Web Ontology Language Application Programming Interface to support ontology-based reasoning. We have developed an efficient ontology management module that automatically updates the ontology mappings each time a new version of the Epilepsy and Seizure Ontology is released. The Insight platform features a Role-based Access Control module to authenticate and effectively manage user access to different research studies. User access to Insight is managed by the Managing Epilepsy Well Network database steering committee consisting of representatives of all current collaborating centers of the Managing Epilepsy Well Network. New research studies are being continuously added to the Insight database and the size as well as the unique coverage of the dataset allows investigators to conduct

  20. Product- and Process Units in the CRITT Translation Process Research Database

    DEFF Research Database (Denmark)

    Carl, Michael

    The first version of the "Translation Process Research Database" (TPR DB v1.0) was released In August 2012, containing logging data of more than 400 translation and text production sessions. The current version of the TPR DB, (v1.4), contains data from more than 940 sessions, which represents more...... than 300 hours of text production. The database provides the raw logging data, as well as Tables of pre-processed product- and processing units. The TPR-DB includes various types of simple and composed product and process units that are intended to support the analysis and modelling of human text...... reception, production, and translation processes. In this talk I describe some of the functions and features of the TPR-DB v1.4, and how they can be deployed in empirical human translation process research....

  1. Dental health services research utilizing comprehensive clinical databases and information technology.

    Science.gov (United States)

    Hayden, W J

    1997-01-01

    Marketplace pressures for accountability in dentistry have made clear dental delivery systems' weaknesses in information generation, management, and analysis methods. Without this type of information, dentistry is unable to quantify and document the outcomes of the dental care services it provides. The Pew Health Professions Commission and the Institute of Medicine both suggest that dental schools should be among the leaders in the development and teaching of dental information capabilities, as well as the source of fundamental dental health services research. This paper argues that dental schools are the logical location for the development of valid, reliable, and acceptable health services research methods and databases. It describes the development of an insurance claims database to demonstrate the types of investigations possible, as well as the weaknesses and shortcomings of pure administrative data. PMID:9024342

  2. Development of the Database for Environmental Sound Research and Application (DESRA: Design, Functionality, and Retrieval Considerations

    Directory of Open Access Journals (Sweden)

    Brian Gygi

    2010-01-01

    Full Text Available Theoretical and applied environmental sounds research is gaining prominence but progress has been hampered by the lack of a comprehensive, high quality, accessible database of environmental sounds. An ongoing project to develop such a resource is described, which is based upon experimental evidence as to the way we listen to sounds in the world. The database will include a large number of sounds produced by different sound sources, with a thorough background for each sound file, including experimentally obtained perceptual data. In this way DESRA can contain a wide variety of acoustic, contextual, semantic, and behavioral information related to an individual sound. It will be accessible on the Internet and will be useful to researchers, engineers, sound designers, and musicians.

  3. A Temporal Abstraction-based Extract, Transform and Load Process for Creating Registry Databases for Research

    OpenAIRE

    Post, Andrew; Kurc, Tahsin; Overcash, Marc; Cantrell, Dedra; Morris, Tim; Eckerson, Kristi; Tsui, Circe; Willey, Terry; Quyyumi, Arshed; Eapen, Danny; Umpierrez, Guillermo; Ziemer, David; Saltz, Joel

    2011-01-01

    In the CTSA era there is great interest in aggregating and comparing populations across institutions. These sites likely represent data differently in their clinical data warehouses and other databases. Clinical data warehouses frequently are structured in a generalized way that supports many constituencies. For research, there is a need to transform these heterogeneous data into a shared representation, and to perform categorization and interpretation to optimize the data representation for ...

  4. Development of a Local Entomological Database for Education and Research using Simulation (Virtual) Methods

    OpenAIRE

    Khater, Emad I.; Mona G. Mahmoud; Enas H. Ghallab; Magdi G. Shehata; Yasser M. Abd El-Latif

    2014-01-01

    Bioinformatics has been regarded as one of the rapidly-evolving fields with enormous impact on the history of life and biomedical sciences. It is an interdisciplinary science that integrates life sciences, mathematics and computer science in order to extract meaningful biological insights from large data sets of raw DNA and protein sequences. Our objective was the development of an entomogenomics database (provisionally named EntomDB) for education and research in entomology (entomology is th...

  5. Genomics and Public Health Research: Can the State Allow Access to Genomic Databases?

    Directory of Open Access Journals (Sweden)

    M Stanton Jean

    2012-04-01

    Full Text Available Because many diseases are multifactorial disorders,the scientific progress in genomics and genetics should be taken into consideration in public health research. In this context, genomic databases will constitute an important source of information. Consequently, it is important to identify and characterize the State's role and authority on matters related to public health,in order to verify whether it has access to such databases while engaging in public health genomic research. We first consider the evolution of the concept of public health, as well as its core functions, using a comparative approach (e.g. WHO, PAHO, CDC and the Canadian province of Quebec. Following an analysis of relevant Quebec legislation, the precautionary principle is examined as a possible avenue to justify State access to and use of genomic databases for research purposes. Finally, we consider the Influenza pandemic plans developed by WHO, Canada, and Quebec,as examples of key tools framing public health decision-making process.We observed that State powers in public health, are not,in Quebec,well adapted to the expansion of genomics research.We propose that the scope of the concept of research in public health should be clear and include the following characteristics:a commitment to the health and well-being of the population and to their determinants; the inclusion of both applied research and basic research; and, an appropriate model of governance (authorization, follow-up,consent, etc..We also suggest that the strategic approach version of the precautionary principle could guide collective choices in these matters.

  6. The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2016 Update on Research.

    Science.gov (United States)

    Jacobs, Marshall L; Jacobs, Jeffrey P; Pasquali, Sara K; Hill, Kevin D; Hornik, Christoph; O'Brien, Sean M; Shahian, David M; Habib, Robert H; Edwards, Fred H

    2016-09-01

    The Society of Thoracic Surgeons Congenital Heart Surgery Database (STS CHSD) is the largest congenital and pediatric cardiac surgical clinical data registry in the world. With more than 400,000 total operations from nearly all centers performing pediatric and congenital heart operations in North America, the STS CHSD is an unparalleled platform for clinical investigation, outcomes research, and quality improvement activities in this subspecialty. In 2015, several major original publications reported analyses of data in the CHSD pertaining to specific diagnostic and procedural groups, age-defined cohorts, or the entire population of patients in the database. Additional publications reported the most recent development, evaluation, and application of metrics for quality measurement and reporting of pediatric and congenital heart operation outcomes. This use of the STS CHSD for outcomes research and for quality measurement continues to expand as database participation and the available wealth of data in it continue to grow. This article reviews outcomes research and quality improvement articles published in 2015 based on STS CHSD data. PMID:27492669

  7. The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2016 Update on Research.

    Science.gov (United States)

    Jacobs, Marshall L; Jacobs, Jeffrey P; Pasquali, Sara K; Hill, Kevin D; Hornik, Christoph; O'Brien, Sean M; Shahian, David M; Habib, Robert H; Edwards, Fred H

    2016-09-01

    The Society of Thoracic Surgeons Congenital Heart Surgery Database (STS CHSD) is the largest congenital and pediatric cardiac surgical clinical data registry in the world. With more than 400,000 total operations from nearly all centers performing pediatric and congenital heart operations in North America, the STS CHSD is an unparalleled platform for clinical investigation, outcomes research, and quality improvement activities in this subspecialty. In 2015, several major original publications reported analyses of data in the CHSD pertaining to specific diagnostic and procedural groups, age-defined cohorts, or the entire population of patients in the database. Additional publications reported the most recent development, evaluation, and application of metrics for quality measurement and reporting of pediatric and congenital heart operation outcomes. This use of the STS CHSD for outcomes research and for quality measurement continues to expand as database participation and the available wealth of data in it continue to grow. This article reviews outcomes research and quality improvement articles published in 2015 based on STS CHSD data.

  8. Human health risk assessment database, 'the NHSRC toxicity value database': Supporting the risk assessment process at US EPA's National Homeland Security Research Center

    International Nuclear Information System (INIS)

    The toxicity value database of the United States Environmental Protection Agency's (EPA) National Homeland Security Research Center has been in development since 2004. The toxicity value database includes a compilation of agent property, toxicity, dose-response, and health effects data for 96 agents: 84 chemical and radiological agents and 12 biotoxins. The database is populated with multiple toxicity benchmark values and agent property information from secondary sources, with web links to the secondary sources, where available. A selected set of primary literature citations and associated dose-response data are also included. The toxicity value database offers a powerful means to quickly and efficiently gather pertinent toxicity and dose-response data for a number of agents that are of concern to the nation's security. This database, in conjunction with other tools, will play an important role in understanding human health risks, and will provide a means for risk assessors and managers to make quick and informed decisions on the potential health risks and determine appropriate responses (e.g., cleanup) to agent release. A final, stand alone MS ACESSS working version of the toxicity value database was completed in November, 2007

  9. Fine-grained policy control in U.S. Army Research Laboratory (ARL) multimodal signatures database

    Science.gov (United States)

    Bennett, Kelly; Grueneberg, Keith; Wood, David; Calo, Seraphin

    2014-06-01

    The U.S. Army Research Laboratory (ARL) Multimodal Signatures Database (MMSDB) consists of a number of colocated relational databases representing a collection of data from various sensors. Role-based access to this data is granted to external organizations such as DoD contractors and other government agencies through a client Web portal. In the current MMSDB system, access control is only at the database and firewall level. In order to offer finer grained security, changes to existing user profile schemas and authentication mechanisms are usually needed. In this paper, we describe a software middleware architecture and implementation that allows fine-grained access control to the MMSDB at a dataset, table, and row level. Result sets from MMSDB queries issued in the client portal are filtered with the use of a policy enforcement proxy, with minimal changes to the existing client software and database. Before resulting data is returned to the client, policies are evaluated to determine if the user or role is authorized to access the data. Policies can be authored to filter data at the row, table or column level of a result set. The system uses various technologies developed in the International Technology Alliance in Network and Information Science (ITA) for policy-controlled information sharing and dissemination1. Use of the Policy Management Library provides a mechanism for the management and evaluation of policies to support finer grained access to the data in the MMSDB system. The GaianDB is a policy-enabled, federated database that acts as a proxy between the client application and the MMSDB system.

  10. Computer-Aided Systems Engineering for Flight Research Projects Using a Workgroup Database

    Science.gov (United States)

    Mizukami, Masahi

    2004-01-01

    An online systems engineering tool for flight research projects has been developed through the use of a workgroup database. Capabilities are implemented for typical flight research systems engineering needs in document library, configuration control, hazard analysis, hardware database, requirements management, action item tracking, project team information, and technical performance metrics. Repetitive tasks are automated to reduce workload and errors. Current data and documents are instantly available online and can be worked on collaboratively. Existing forms and conventional processes are used, rather than inventing or changing processes to fit the tool. An integrated tool set offers advantages by automatically cross-referencing data, minimizing redundant data entry, and reducing the number of programs that must be learned. With a simplified approach, significant improvements are attained over existing capabilities for minimal cost. By using a workgroup-level database platform, personnel most directly involved in the project can develop, modify, and maintain the system, thereby saving time and money. As a pilot project, the system has been used to support an in-house flight experiment. Options are proposed for developing and deploying this type of tool on a more extensive basis.

  11. Aspergillus flavus Blast2GO gene ontology database: elevated growth temperature alters amino acid metabolism

    Science.gov (United States)

    The availability of a representative gene ontology (GO) database is a prerequisite for a successful functional genomics study. Using online Blast2GO resources we constructed a GO database of Aspergillus flavus. Of the predicted total 13,485 A. flavus genes 8,987 were annotated with GO terms. The mea...

  12. Construction of a bibliographic information database and development of retrieval system for research reports in nuclear science and technology (II)

    Energy Technology Data Exchange (ETDEWEB)

    Han, Duk Haeng; Kim, Tae Whan; Choi, Kwang; Yoo, An Na; Keum, Jong Yong; Kim, In Kwon [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-05-01

    The major goal of this project is to construct a bibliographic information database in nuclear engineering and to develop a prototype retrieval system. To give an easy access to microfiche research report, this project has accomplished the construction of microfiche research reports database and the development of retrieval system. The results of the project are as follows; 1. Microfiche research reports database was constructed by downloading from DOE Energy, NTIS, INIS. 2. The retrieval system was developed in host and web version using access point such as title, abstracts, keyword, report number. 6 tabs., 8 figs., 11 refs. (Author) .new.

  13. The Traumatic Brain Injury Model Systems: a longitudinal database, research, collaboration and knowledge translation.

    Science.gov (United States)

    Hammond, F M; Malec, J F

    2010-12-01

    In 1988, the National Institute on Disability and Rehabilitation Research (NIDRR) launched the Traumatic Brain Injury Model Systems (TBIMS) program, creating the longest and largest longitudinal database on individuals with moderate-to-severe traumatic brain injury (TBI) available today. In addition to sustaining the longitudinal database, centers that successfully compete to be part of the TBIMS centers are also expected to complete local and collaborative research projects to further scientific knowledge about TBI. The research has focused on areas of the NIDRR Long Range Plan which emphasizes employment, health and function, technology for access and function, independent living and community integration, and other associated disability research areas. Centers compete for funded participation in the TBIMS on a 5-year cycle. Dissemination of scientific knowledge gained through the TBIMS is the responsibility of both individual centers and the TBIMS as a whole. This is accomplished through multiple venues that target a broad audience of those who need to receive the information and learn how to best apply it to practice. The sites produce many useful websites, manuals, publications and other materials to accomplish this translation of knowledge to practice.

  14. What Do They Tell Their Students? Business Faculty Acceptance of the Web and Library Databases for Student Research

    Science.gov (United States)

    Dewald, Nancy H.

    2005-01-01

    Business faculty were surveyed as to their use of free Web resources and subscription databases for their own and their students' research. A much higher percentage of respondents either require or encourage Web use by their students than require or encourage database use, though most also advise use of multiple sources.

  15. Research progress and prospects of low phytic acid crops

    International Nuclear Information System (INIS)

    The contents and deposit forms of phytic acid and its physiological functions were summarized. The researches on the molecular genetic basis and possible mechanisms of low phytic acid mutations were reviewed, and the future perspectives were discussed. (authors)

  16. A database of chromatographic properties and mass spectra of fatty acid methyl esters from omega-3 products.

    Science.gov (United States)

    Wasta, Ziar; Mjøs, Svein A

    2013-07-19

    Fatty acids in products claimed to contain oils with the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were analyzed as fatty acid methyl esters by gas chromatography-mass spectrometry using electron impact ionization. To cover the variation in products on the market, the 20 products that were studied in detail were selected from a larger sample set by statistical methodology. The samples were analyzed on two different stationary phases (polyethylene glycol and cyanopropyl) and the fatty acid methyl esters were identified by methodology that combines the mass spectra and retention indices into a single score value. More that 100 fatty acids had a chromatographic area above 0.1% of the total, in at least one product. Retention indices are reported as equivalent chain lengths, and overlap patterns on the two columns are discussed. Both columns were found suitable for analysis of major and nutritionally important fatty acids, but the large number of minor compounds that may act as interferents will be problematic if low limits of quantification are required in analyses of similar sample types. A database of mass spectral libraries and equivalent chain lengths of the detected compounds has been compiled and is available online. PMID:23773584

  17. The Corvids Literature Database--500 years of ornithological research from a crow's perspective.

    Science.gov (United States)

    Droege, Gabriele; Töpfer, Till

    2016-01-01

    Corvids (Corvidae) play a major role in ornithological research. Because of their worldwide distribution, diversity and adaptiveness, they have been studied extensively. The aim of the Corvids Literature Database (CLD, http://www.corvids.de/cld) is to record all publications (citation format) on all extant and extinct Crows, Ravens, Jays and Magpies worldwide and tag them with specific keywords making them available for researchers worldwide. The self-maintained project started in 2006 and today comprises 8000 articles, spanning almost 500 years. The CLD covers publications from 164 countries, written in 36 languages and published by 8026 authors in 1503 journals (plus books, theses and other publications). Forty-nine percent of all records are available online as full-text documents or deposited in the physical CLD archive. The CLD contains 442 original corvid descriptions. Here, we present a metadata assessment of articles recorded in the CLD including a gap analysis and prospects for future research. Database URL: http://www.corvids.de/cld. PMID:26868053

  18. SPIN query tools for de-identified research on a humongous database.

    Science.gov (United States)

    McDonald, Clement J; Dexter, Paul; Schadow, Gunther; Chueh, Henry C; Abernathy, Greg; Hook, John; Blevins, Lonnie; Overhage, J Marc; Berman, Jules J

    2005-01-01

    The Shared Pathology Informatics Network (SPIN), a research initiative of the National Cancer Institute, will allow for the retrieval of more than 4 million pathology reports and specimens. In this paper, we describe the special query tool as developed for the Indianapolis/Regenstrief SPIN node, integrated into the ever-expanding Indiana Network for Patient care (INPC). This query tool allows for the retrieval of de-identified data sets using complex logic, auto-coded final diagnoses, and intrinsically supports multiple types of statistical analyses. The new SPIN/INPC database represents a new generation of the Regenstrief Medical Record system - a centralized, but federated system of repositories. PMID:16779093

  19. Research Update: The materials genome initiative: Data sharing and the impact of collaborative ab initio databases

    Science.gov (United States)

    Jain, Anubhav; Persson, Kristin A.; Ceder, Gerbrand

    2016-05-01

    Materials innovations enable new technological capabilities and drive major societal advancements but have historically required long and costly development cycles. The Materials Genome Initiative (MGI) aims to greatly reduce this time and cost. In this paper, we focus on data reuse in the MGI and, in particular, discuss the impact of three different computational databases based on density functional theory methods to the research community. We also discuss and provide recommendations on technical aspects of data reuse, outline remaining fundamental challenges, and present an outlook on the future of MGI's vision of data sharing.

  20. Monitoring of equine health in Denmark: the importance, purpose, research areas and content of a future database.

    Science.gov (United States)

    Hartig, Wendy; Houe, Hans; Andersen, Pia Haubro

    2013-04-01

    The plentiful data on Danish horses are currently neither organized nor easily accessible, impeding register-based epidemiological studies on Danish horses. A common database could be beneficial. In principle, databases can contain a wealth of information, but no single database can serve every purpose. Hence the establishment of a Danish equine health database should be preceded by careful consideration of its purpose and content, and stakeholder attitudes should be investigated. The objectives of the present study were to identify stakeholder attitudes to the importance, purpose, research areas and content of a health database for horses in Denmark. A cross-sectional study was conducted with 13 horse-related stakeholder groups in Denmark. The groups surveyed included equine veterinarians, researchers, veterinary students, representatives from animal welfare organizations, horse owners, trainers, farriers, authority representatives, ordinary citizens, and representatives from laboratories, insurance companies, medical equipment companies and pharmaceutical companies. Supplementary attitudes were inferred from qualitative responses. The overall response rate for all stakeholder groups was 45%. Stakeholder group-specific response rates were 27-80%. Sixty-eight percent of questionnaire respondents thought a national equine health database was important. Most respondents wanted the database to contribute to improved horse health and welfare, to be used for research into durability and disease heritability, and to serve as a basis for health declarations for individual horses. The generally preferred purpose of the database was thus that it should focus on horse health and welfare rather than on performance or food safety, and that it should be able to function both at a population and an individual horse level. In conclusion, there is a positive attitude to the establishment of a health database for Danish horses. These results could enrich further reflection on the

  1. Research for amino acids in lunar samples.

    Science.gov (United States)

    Gehrke, C. W.; Zumwalt, R. W.; Kuo, K.; Rash, J. J.; Aue , W. A.; Stalling, D. L.; Kvenvolden, K. A.; Ponnamperuma, C.

    1972-01-01

    The study was primarily directed toward the examination of Apollo 14 lunar fines for indigenous amino acids or materials which could be converted to amino acids on hydrolysis with 6 N hydrochloric acid. Initial experiments were conducted to confirm the integrity of the derivatization reactions and reagents, and to optimize the gas-liquid chromatographic (GLC) instrumental and chromatographic system for the separation and flame ionization detection of the amino acid derivatives. In studies on the recovery of amino acids added to lunar fines, low recoveries were obtained when 10 ng of each amino acid were added to 50 mg of virgin fines, but the subsequent addition of 50 ng of each to the previously extracted sample resulted in much higher recoveries.

  2. Food-pics: an image database for experimental research on eating and appetite.

    Science.gov (United States)

    Blechert, Jens; Meule, Adrian; Busch, Niko A; Ohla, Kathrin

    2014-01-01

    Our current environment is characterized by the omnipresence of food cues. The sight and smell of real foods, but also graphically depictions of appetizing foods, can guide our eating behavior, for example, by eliciting food craving and influencing food choice. The relevance of visual food cues on human information processing has been demonstrated by a growing body of studies employing food images across the disciplines of psychology, medicine, and neuroscience. However, currently used food image sets vary considerably across laboratories and image characteristics (contrast, brightness, etc.) and food composition (calories, macronutrients, etc.) are often unspecified. These factors might have contributed to some of the inconsistencies of this research. To remedy this, we developed food-pics, a picture database comprising 568 food images and 315 non-food images along with detailed meta-data. A total of N = 1988 individuals with large variance in age and weight from German speaking countries and North America provided normative ratings of valence, arousal, palatability, desire to eat, recognizability and visual complexity. Furthermore, data on macronutrients (g), energy density (kcal), and physical image characteristics (color composition, contrast, brightness, size, complexity) are provided. The food-pics image database is freely available under the creative commons license with the hope that the set will facilitate standardization and comparability across studies and advance experimental research on the determinants of eating behavior. PMID:25009514

  3. DMPD: Nucleic acid-sensing TLRs as modifiers of autoimmunity. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 17082566 Nucleic acid-sensing TLRs as modifiers of autoimmunity. Deane JA, Bolland ...S. J Immunol. 2006 Nov 15;177(10):6573-8. (.png) (.svg) (.html) (.csml) Show Nucleic acid-sensing TLRs as mo...difiers of autoimmunity. PubmedID 17082566 Title Nucleic acid-sensing TLRs as modifiers of autoimmunity. Aut

  4. National Database for Autism Research (NDAR): Big Data Opportunities for Health Services Research and Health Technology Assessment.

    Science.gov (United States)

    Payakachat, Nalin; Tilford, J Mick; Ungar, Wendy J

    2016-02-01

    The National Database for Autism Research (NDAR) is a US National Institutes of Health (NIH)-funded research data repository created by integrating heterogeneous datasets through data sharing agreements between autism researchers and the NIH. To date, NDAR is considered the largest neuroscience and genomic data repository for autism research. In addition to biomedical data, NDAR contains a large collection of clinical and behavioral assessments and health outcomes from novel interventions. Importantly, NDAR has a global unique patient identifier that can be linked to aggregated individual-level data for hypothesis generation and testing, and for replicating research findings. As such, NDAR promotes collaboration and maximizes public investment in the original data collection. As screening and diagnostic technologies as well as interventions for children with autism are expensive, health services research (HSR) and health technology assessment (HTA) are needed to generate more evidence to facilitate implementation when warranted. This article describes NDAR and explains its value to health services researchers and decision scientists interested in autism and other mental health conditions. We provide a description of the scope and structure of NDAR and illustrate how data are likely to grow over time and become available for HSR and HTA. PMID:26446859

  5. National Database for Autism Research (NDAR): Big Data Opportunities for Health Services Research and Health Technology Assessment.

    Science.gov (United States)

    Payakachat, Nalin; Tilford, J Mick; Ungar, Wendy J

    2016-02-01

    The National Database for Autism Research (NDAR) is a US National Institutes of Health (NIH)-funded research data repository created by integrating heterogeneous datasets through data sharing agreements between autism researchers and the NIH. To date, NDAR is considered the largest neuroscience and genomic data repository for autism research. In addition to biomedical data, NDAR contains a large collection of clinical and behavioral assessments and health outcomes from novel interventions. Importantly, NDAR has a global unique patient identifier that can be linked to aggregated individual-level data for hypothesis generation and testing, and for replicating research findings. As such, NDAR promotes collaboration and maximizes public investment in the original data collection. As screening and diagnostic technologies as well as interventions for children with autism are expensive, health services research (HSR) and health technology assessment (HTA) are needed to generate more evidence to facilitate implementation when warranted. This article describes NDAR and explains its value to health services researchers and decision scientists interested in autism and other mental health conditions. We provide a description of the scope and structure of NDAR and illustrate how data are likely to grow over time and become available for HSR and HTA.

  6. Development of a Local Entomological Database for Education and Research using Simulation (Virtual Methods

    Directory of Open Access Journals (Sweden)

    Emad I. Khater

    2014-01-01

    Full Text Available Bioinformatics has been regarded as one of the rapidly-evolving fields with enormous impact on the history of life and biomedical sciences. It is an interdisciplinary science that integrates life sciences, mathematics and computer science in order to extract meaningful biological insights from large data sets of raw DNA and protein sequences. Our objective was the development of an entomogenomics database (provisionally named EntomDB for education and research in entomology (entomology is the science of insects. This DB includes DNA/protein sequence data selected from genomes of major insect models of importance in biology and biomedical research. EntomDB will represent a customized easy, interactive and self-learning resource tool for beginner users in poor-resource settings. This will enable the users to learn basic skills in bioinformatics and genomics, needlessly to search through the numerous databases currently available on the World-Wide Web with their complex interfaces and contents. EntomDB will help students and young researchers in studying the primary structure, splicing, and translation and predict function of different genes by using simple simulation methods. It is also designed to be adaptable to work off-line, in case no internet connection is available. EntomDB is primarily designed for entomology discipline; however, it can easily be adapted for other disciplines in life and biomedical sciences. EntomDB will have important educational and developmental outcomes in promoting bioinformatics learning in the developing world and provide affordable first-level training for advanced degree and research levels.

  7. Amino acid sequences of predicted proteins and their annotation for 95 organism species. - Gclust Server | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available ID ID of a sequence Cluster ID ID of cluster. gclust_cluster is referenced. Annotation in original... database Annotation at the original website Species Species name Length Amino acid sequen

  8. Acid mine drainage research in Canada

    International Nuclear Information System (INIS)

    Acidic drainage resulting from base metal, precious metal, and uranium mining is the largest single environmental problems facing the Canadian mining industry today. Technologies to prevent acidic drainage from occurring in waste rock piles and tailings sites, and on the walls of open pits and underground mines, need to be developed and demonstrated. There are two grounds in Canada which have accepted this challenge: the national Mine Environment Neutral Drainage (MEND) program and the British Columbia Acid Mine Drainage (BC AMD) Task Force. This paper summarizes the activities of these two organizations

  9. [Spanish contribution to the creation of a European analytical database of trans-fatty acids].

    Science.gov (United States)

    Cuadrado, C; Carbajal, A; Núñez, C; Ruiz-Roso, B; Moreiras, O

    1998-01-01

    Within the AAIR Program of the EU titled Evaluation of the Ingestion of Trans Fatty Acids (FA) and its association with cardiovascular risk factors in European countries (TRANSFAIR), which is being carried out in 16 countries with different alimentary habits, among which is our country, we have developed the following study. Based on the information derived from the last National Nutrition and Feeding Study (ENNA-3), we have made up a list of foods which make up 95% of the total ingestion of lipids, and it also includes those which although they are not included within this percentage, may have an especially high trans isomer content as a result of their processing. The foods selected for the analysis belong to different food groups: cereals, milk products, oils and fats, meats, various, and pre-cooked foods, until making up a total of 100 foods for each country. The central analysis laboratory is that of the Department of Human Nutrition, TNO Nutrition and Food Research, Zeist (The Netherlands). In each sample, in addition to the total lipids, one determines the saturated and unsaturated fatty acids, including the cis and trans isomers. The trans FA's measured were: C14:1 T9, C16:1 T9, C18:1 T, C18:2 T, C18:3 T + C20:1 T, C20:2 T11,14, and C22:1 T13. Of the samples analyzed, the highest percentages of trans FA with respect to the total FA corresponded to the following foods: French fries, pre-cooked and frozen croquettes sliced bread, margarine, cakes, and frozen mille feuilles dough of different industrial brands. The lowest percentages of trans FA's were found in refined vegetable oils (sunflower and olive), those used for deep frying, and those discarded in catering, as well as in some commercial brands of cookies and ice creams. Pure chocolate, different brands of sweetened powdered cocoa, and ready to make chocolate, did not contain and trans FA. PMID:9578683

  10. TarNet: An Evidence-Based Database for Natural Medicine Research

    Science.gov (United States)

    Ren, Guomin; Sun, Guibo; Sun, Xiaobo

    2016-01-01

    Background Complex diseases seriously threaten human health. Drug discovery approaches based on “single genes, single drugs, and single targets” are limited in targeting complex diseases. The development of new multicomponent drugs for complex diseases is imperative, and the establishment of a suitable solution for drug group-target protein network analysis is a key scientific problem that must be addressed. Herbal medicines have formed the basis of sophisticated systems of traditional medicine and have given rise to some key drugs that remain in use today. The search for new molecules is currently taking a different route, whereby scientific principles of ethnobotany and ethnopharmacognosy are being used by chemists in the discovery of different sources and classes of compounds. Results In this study, we developed TarNet, a manually curated database and platform of traditional medicinal plants with natural compounds that includes potential bio-target information. We gathered information on proteins that are related to or affected by medicinal plant ingredients and data on protein–protein interactions (PPIs). TarNet includes in-depth information on both plant–compound–protein relationships and PPIs. Additionally, TarNet can provide researchers with network construction analyses of biological pathways and protein–protein interactions (PPIs) associated with specific diseases. Researchers can upload a gene or protein list mapped to our PPI database that has been manually curated to generate relevant networks. Multiple functions are accessible for network topological calculations, subnetwork analyses, pathway analyses, and compound–protein relationships. Conclusions TarNet will serve as a useful analytical tool that will provide information on medicinal plant compound-affected proteins (potential targets) and system-level analyses for systems biology and network pharmacology researchers. TarNet is freely available at http://www.herbbol.org:8001/tarnet

  11. Turning text into research networks: information retrieval and computational ontologies in the creation of scientific databases.

    Directory of Open Access Journals (Sweden)

    Flávio Ceci

    Full Text Available BACKGROUND: Web-based, free-text documents on science and technology have been increasing growing on the web. However, most of these documents are not immediately processable by computers slowing down the acquisition of useful information. Computational ontologies might represent a possible solution by enabling semantically machine readable data sets. But, the process of ontology creation, instantiation and maintenance is still based on manual methodologies and thus time and cost intensive. METHOD: We focused on a large corpus containing information on researchers, research fields, and institutions. We based our strategy on traditional entity recognition, social computing and correlation. We devised a semi automatic approach for the recognition, correlation and extraction of named entities and relations from textual documents which are then used to create, instantiate, and maintain an ontology. RESULTS: We present a prototype demonstrating the applicability of the proposed strategy, along with a case study describing how direct and indirect relations can be extracted from academic and professional activities registered in a database of curriculum vitae in free-text format. We present evidence that this system can identify entities to assist in the process of knowledge extraction and representation to support ontology maintenance. We also demonstrate the extraction of relationships among ontology classes and their instances. CONCLUSION: We have demonstrated that our system can be used for the conversion of research information in free text format into database with a semantic structure. Future studies should test this system using the growing number of free-text information available at the institutional and national levels.

  12. Delivering research output to the user using ICT services: Marine contamination database web interface

    International Nuclear Information System (INIS)

    This project is about developing a web-based interface for accessing the Marine Contamination database records. The system contains of information pertaining to the occurrence of contaminants and natural elements in the marine eco-system based on samples taken at various locations within the shores of Malaysia in the form of sediment, seawater and marine biota. It represents a systematic approach for recording, storing and managing the vast amount of marine environmental data collected as output of the Marine Contamination and Transport Phenomena Research Project since 1990. The resultant collection of data is to form the background information (or baseline data) which could later be used to monitor the level of marine environmental pollutions around the country. Data collected from the various sampling and related laboratory activities are previously kept in conventional forms such as Excel worksheets and other documents, both in digital and/or paper form. With the help of modern database storage and retrieval techniques, the task of storage and retrieval of data has been made easier and manageable. It can also provide easy access to other parties who are interested in the data. (author)

  13. A Green's function database platform for seismological research and education: applications and examples

    Science.gov (United States)

    Heimann, Sebastian; Kriegerowski, Marius; Dahm, Torsten; Simone, Cesca; Wang, Rongjiang

    2016-04-01

    The study of seismic sources from measured waveforms requires synthetic elementary seismograms (Green's functions, GF) calculated for specific earth models and source receiver geometries. Since the calculation of GFs is computationally expensive and requires careful parameter testing and quality control, pre-calculated GF databases, which can be re-used for different types of applications, can be of advantage. We developed a GF database web platform for the seismological community (http://kinherd.org/), where a researcher can share Green's function stores and retrieve synthetic seismograms on the fly for various point and extended earthquake source models for many different earth models at local, regional and global scale. This web service is part of a rich new toolset for the creation and handling of Green's functions and synthetic seismograms (http://emolch.github.com/pyrocko/gf). It can be used off-line or in client mode. We demonstrate core features of the GF platform with different applications on global, regional and local scales. These include the automatic inversion of kinematic source parameter from teleseismic body waves, the improved depth estimate of shallow induced earthquakes from regional seismological arrays, or the relative moment tensor inversion of local earthquakes from volcanic induced seismicity.

  14. Research progress in muscle-derived stem cells Literature retrieval results based on international database

    Institute of Scientific and Technical Information of China (English)

    Li Zhang; Wei Wang

    2012-01-01

    OBJECTIVE: To identify global research trends of muscle-derived stem cells (MDSCs) using a bibliometric analysis of the Web of Science, Research Portfolio Online Reporting Tools of the National Institutes of Health (NIH), and the Clinical Trials registry database (ClinicalTrials.gov). DATA RETRIEVAL: We performed a bibliometric analysis of data retrievals for MDSCs from 2002 to 2011 using the Web of Science, NIH, and ClinicalTrials.gov. MAIN OUTCOME MEASURES: (1) Type of literature; (2) annual publication output; (3) distribution according to journals; (4) distribution according to country; (5) distribution according to institution; (6) top cited authors over the last 10 years; (7) projects financially supported by the NIH; and (8) clinical trials registered.RESULTS: (1) In all, 802 studies on MDSCs appeared in the Web of Science from 2002 to 2011, almost half of which derived from American authors and institutes. The number of studies on MDSCs has gradually increased over the past 10 years. Most papers on MDSCs appeared in journals with a particular focus on cell biology research, such as Experimental Cell Research, Journal of Cell Science, and PLoS One. (2) Eight MDSC research projects have received over US$6 billion in funding from the NIH. The current project led by Dr. Johnny Huard of the University of Pittsburgh-"Muscle-Based Tissue Engineering to Improve Bone Healing"-is supported by the NIH. Dr. Huard has been the most productive and top-cited author in the field of gene therapy and adult stem cell research in the Web of Science over last 10 years. (3) On ClinicalTrials.gov, "Muscle Derived Cell Therapy for Bladder Exstrophy Epispadias Induced Incontinence" Phase 1 is registered and sponsored by Johns Hopkins University and has been led by Dr. John P. Gearhart since November 2009.CONCLUSION: From our analysis of the literature and research trends, we found that MDSCs may offer further benefits in regenerative medicine.

  15. Hydrogen bonding in oxalic acid and its complexes: A database study of neutron structures

    Indian Academy of Sciences (India)

    R Chitra; Amit Das; R R Choudhury; M Ramanadham; R Chidambaram

    2004-08-01

    The basic result of carboxylic group that the oxygen atom of the –OH never seems to be a hydrogen bond acceptor is violated in the cases, namely urea oxalic acid and bis urea oxalic acid complexes, where the hydroxyl oxygen atom is an acceptor of a weak N–H... O hydrogen bond. The parameters of this hydrogen bond, respectively in these structures are: hydrogen acceptor distance 2.110 Å and 2.127 Å and the bending angle at hydrogen, 165.6° and 165.8°. The bond strength around the hydroxyl oxygen is close to 1.91 valence units, indicating that it has hardly any strength left to form hydrogen bonds. These two structures being highly planar, force the formation of this hydrogen bond. As oxalic acid is the common moiety, the structures of the two polymorphs, -oxalic acid and -oxalic acid, also were looked into in terms of hydrogen bonding and packing.

  16. The human studies database project: federating human studies design data using the ontology of clinical research.

    Science.gov (United States)

    Sim, Ida; Carini, Simona; Tu, Samson; Wynden, Rob; Pollock, Brad H; Mollah, Shamim A; Gabriel, Davera; Hagler, Herbert K; Scheuermann, Richard H; Lehmann, Harold P; Wittkowski, Knut M; Nahm, Meredith; Bakken, Suzanne

    2010-01-01

    Human studies, encompassing interventional and observational studies, are the most important source of evidence for advancing our understanding of health, disease, and treatment options. To promote discovery, the design and results of these studies should be made machine-readable for large-scale data mining, synthesis, and re-analysis. The Human Studies Database Project aims to define and implement an informatics infrastructure for institutions to share the design of their human studies. We have developed the Ontology of Clinical Research (OCRe) to model study features such as design type, interventions, and outcomes to support scientific query and analysis. We are using OCRe as the reference semantics for federated data sharing of human studies over caGrid, and are piloting this implementation with several Clinical and Translational Science Award (CTSA) institutions. PMID:21347149

  17. Proyecto AVIS: a Spanish open access bird database available for research

    Directory of Open Access Journals (Sweden)

    Sara Varela

    2014-12-01

    Full Text Available Proyecto AVIS1 is an open access citizen science database that stores information collected by amateur ornithologists about bird occurrences and abundance in Spain. Proyecto AVIS was launched in 2005 and today stores data from 415 species (ca. 90% of bird species in Spain; it covers 30% of the Spanish territory, including the Canary Islands in the Atlantic Ocean and the Balearic Islands in the Mediterranean Sea. Here, we acknowledge the work of all the volunteers that have gathered bird records in the field and uploaded these observations over the last 10 years, and introduce Proyecto AVIS to a broader community of biogeographers and macroecologists to promote its use for research

  18. PlantDB – a versatile database for managing plant research

    Directory of Open Access Journals (Sweden)

    Gruissem Wilhelm

    2008-01-01

    Full Text Available Abstract Background Research in plant science laboratories often involves usage of many different species, cultivars, ecotypes, mutants, alleles or transgenic lines. This creates a great challenge to keep track of the identity of experimental plants and stored samples or seeds. Results Here, we describe PlantDB – a Microsoft® Office Access database – with a user-friendly front-end for managing information relevant for experimental plants. PlantDB can hold information about plants of different species, cultivars or genetic composition. Introduction of a concise identifier system allows easy generation of pedigree trees. In addition, all information about any experimental plant – from growth conditions and dates over extracted samples such as RNA to files containing images of the plants – can be linked unequivocally. Conclusion We have been using PlantDB for several years in our laboratory and found that it greatly facilitates access to relevant information.

  19. Creating a data exchange strategy for radiotherapy research: Towards federated databases and anonymised public datasets

    International Nuclear Information System (INIS)

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research in radiation therapy and oncology. The exchange of study data is one of the fundamental principles behind data aggregation and data mining. The possibilities of reproducing the original study results, performing further analyses on existing research data to generate new hypotheses or developing computational models to support medical decisions (e.g. risk/benefit analysis of treatment options) represent just a fraction of the potential benefits of medical data-pooling. Distributed machine learning and knowledge exchange from federated databases can be considered as one beyond other attractive approaches for knowledge generation within “Big Data”. Data interoperability between research institutions should be the major concern behind a wider collaboration. Information captured in electronic patient records (EPRs) and study case report forms (eCRFs), linked together with medical imaging and treatment planning data, are deemed to be fundamental elements for large multi-centre studies in the field of radiation therapy and oncology. To fully utilise the captured medical information, the study data have to be more than just an electronic version of a traditional (un-modifiable) paper CRF. Challenges that have to be addressed are data interoperability, utilisation of standards, data quality and privacy concerns, data ownership, rights to publish, data pooling architecture and storage. This paper discusses a framework for conceptual packages of ideas focused on a strategic development for international research data exchange in the field of radiation therapy and oncology

  20. Creating a data exchange strategy for radiotherapy research: towards federated databases and anonymised public datasets.

    Science.gov (United States)

    Skripcak, Tomas; Belka, Claus; Bosch, Walter; Brink, Carsten; Brunner, Thomas; Budach, Volker; Büttner, Daniel; Debus, Jürgen; Dekker, Andre; Grau, Cai; Gulliford, Sarah; Hurkmans, Coen; Just, Uwe; Krause, Mechthild; Lambin, Philippe; Langendijk, Johannes A; Lewensohn, Rolf; Lühr, Armin; Maingon, Philippe; Masucci, Michele; Niyazi, Maximilian; Poortmans, Philip; Simon, Monique; Schmidberger, Heinz; Spezi, Emiliano; Stuschke, Martin; Valentini, Vincenzo; Verheij, Marcel; Whitfield, Gillian; Zackrisson, Björn; Zips, Daniel; Baumann, Michael

    2014-12-01

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research in radiation therapy and oncology. The exchange of study data is one of the fundamental principles behind data aggregation and data mining. The possibilities of reproducing the original study results, performing further analyses on existing research data to generate new hypotheses or developing computational models to support medical decisions (e.g. risk/benefit analysis of treatment options) represent just a fraction of the potential benefits of medical data-pooling. Distributed machine learning and knowledge exchange from federated databases can be considered as one beyond other attractive approaches for knowledge generation within "Big Data". Data interoperability between research institutions should be the major concern behind a wider collaboration. Information captured in electronic patient records (EPRs) and study case report forms (eCRFs), linked together with medical imaging and treatment planning data, are deemed to be fundamental elements for large multi-centre studies in the field of radiation therapy and oncology. To fully utilise the captured medical information, the study data have to be more than just an electronic version of a traditional (un-modifiable) paper CRF. Challenges that have to be addressed are data interoperability, utilisation of standards, data quality and privacy concerns, data ownership, rights to publish, data pooling architecture and storage. This paper discusses a framework for conceptual packages of ideas focused on a strategic development for international research data exchange in the field of radiation therapy and oncology. PMID:25458128

  1. RDD Databases

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This database was established to oversee documents issued in support of fishery research activities including experimental fishing permits (EFP), letters of...

  2. Data quality in European primary care research databases. Report of a workshop held in London September 2013

    OpenAIRE

    Tate, A Rosemary; KALRA, Dipak; Boggon, Rachael; Beloff, Natalia; Puri, Shivani; Williams, Tim

    2014-01-01

    Primary care research databases provide a significant resource for health services and epidemiological research. However since data are recorded primarily for clinical care their suitability for research may vary widely according to the research application or recording practices of individual general practitioners. A methodological approach for characterising data quality is required. We describe a one-day workshop entitled “Towards a common protocol for measuring and monitoring data quality...

  3. Searching biosignal databases by content and context: Research Oriented Integration System for ECG Signals (ROISES).

    Science.gov (United States)

    Kokkinaki, Alexandra; Chouvarda, Ioanna; Maglaveras, Nicos

    2012-11-01

    Technological advances in textile, biosensor and electrocardiography domain induced the wide spread use of bio-signal acquisition devices leading to the generation of massive bio-signal datasets. Among the most popular bio-signals, electrocardiogram (ECG) possesses the longest tradition in bio-signal monitoring and recording, being a strong and relatively robust signal. As research resources are fostered, research community promotes the need to extract new knowledge from bio-signals towards the adoption of new medical procedures. However, integrated access, query and management of ECGs are impeded by the diversity and heterogeneity of bio-signal storage data formats. In this scope, the proposed work introduces a new methodology for the unified access to bio-signal databases and the accompanying metadata. It allows decoupling information retrieval from actual underlying datasource structures and enables transparent content and context based searching from multiple data resources. Our approach is based on the definition of an interactive global ontology which manipulates the similarities and the differences of the underlying sources to either establish similarity mappings or enrich its terminological structure. We also introduce ROISES (Research Oriented Integration System for ECG Signals), for the definition of complex content based queries against the diverse bio-signal data sources. PMID:21397354

  4. Asian Agricultural Research is indexed by CABI,CSA Illumina,AGE and other famous databases in many countries

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers,Asian Agricultural Research eventually passes the extremely strict appraisal,to be indexed by CABI’ s full text repository.CABI is globally acclaimed as one of the most authoritative and prestigious abstract data bases concerning agriculture and forestry.Since inception of publication,Asian Agricultural Research has also been indexed by AGE Database,Naresuan University Library,Rural Development Foundation of India,Royal Tropical Institute and CSA Illumina.Editorial office of Asian Agricultural Research CABI Database CABI Database,one of the most authoritative and prestigious abstract data bases concerning agriculture and forestry,is compiled by Centre for Agricultural Bioscience International.This data base,since 1973,has indexed 5

  5. NOAA's Integrated Tsunami Database: Data for improved forecasts, warnings, research, and risk assessments

    Science.gov (United States)

    Stroker, Kelly; Dunbar, Paula; Mungov, George; Sweeney, Aaron; McCullough, Heather; Carignan, Kelly

    2015-04-01

    The National Oceanic and Atmospheric Administration (NOAA) has primary responsibility in the United States for tsunami forecast, warning, research, and supports community resiliency. NOAA's National Geophysical Data Center (NGDC) and co-located World Data Service for Geophysics provide a unique collection of data enabling communities to ensure preparedness and resilience to tsunami hazards. Immediately following a damaging or fatal tsunami event there is a need for authoritative data and information. The NGDC Global Historical Tsunami Database (http://www.ngdc.noaa.gov/hazard/) includes all tsunami events, regardless of intensity, as well as earthquakes and volcanic eruptions that caused fatalities, moderate damage, or generated a tsunami. The long-term data from these events, including photographs of damage, provide clues to what might happen in the future. NGDC catalogs the information on global historical tsunamis and uses these data to produce qualitative tsunami hazard assessments at regional levels. In addition to the socioeconomic effects of a tsunami, NGDC also obtains water level data from the coasts and the deep-ocean at stations operated by the NOAA/NOS Center for Operational Oceanographic Products and Services, the NOAA Tsunami Warning Centers, and the National Data Buoy Center (NDBC) and produces research-quality data to isolate seismic waves (in the case of the deep-ocean sites) and the tsunami signal. These water-level data provide evidence of sea-level fluctuation and possible inundation events. NGDC is also building high-resolution digital elevation models (DEMs) to support real-time forecasts, implemented at 75 US coastal communities. After a damaging or fatal event NGDC begins to collect and integrate data and information from many organizations into the hazards databases. Sources of data include our NOAA partners, the U.S. Geological Survey, the UNESCO Intergovernmental Oceanographic Commission (IOC) and International Tsunami Information Center

  6. Food-pics: an image database for experimental research on eating and appetite

    Directory of Open Access Journals (Sweden)

    Jens eBlechert

    2014-06-01

    Full Text Available Our current environment is characterized by the omnipresence of food cues. The sight and smell of real foods, but also graphically depictions of appetizing foods, can guide our eating behavior, for example, by eliciting food craving and influencing food choice. The relevance of visual food cues on human information processing has been demonstrated by a growing body of studies employing food images across the disciplines of psychology, medicine, and neuroscience. However, currently used food image sets vary considerably across laboratories and image characteristics (contrast, brightness, etc. and food composition (calories, macronutrients, etc. are often unspecified. These factors might have contributed to some of the inconsistencies of this research. To remedy this, we developed food-pics, a picture database comprising 568 food images and 315 non-food images along with detailed meta-data. A total of N = 1988 individuals with large variance in age and weight from German speaking countries and North America provided normative ratings of valence, arousal, palatability, desire to eat, recognizability and visual complexity. Furthermore, data on macronutrients (g, energy density (kcal, and physical image characteristics (color composition, contrast, brightness, size, complexity are provided. The food-pics image data base is freely available under the creative commons license with the hope that the set will facilitate standardization and comparability across studies and advance experimental research on the determinants of eating behavior.

  7. A synopsis of original research projects published in scientific database in the Russian Federation.

    Science.gov (United States)

    Smirnova, Daria; Pavlichenko, Alexey; Karpenko, Olga; Schmeleva, Liubov; Morozov, Petr

    2015-06-01

    The article describes the current state of scientific publications in the field of psychiatry in the Russian Federation. Issues of academic dissertations, lack of access to recent Russian language research in foreign databases, and recent reforms in the Ministry of Education and Science for overcoming these limitations are discussed in detail. Four exemplary dissertation studies published in Russian language are summarized. The first research examines the contribution of patient's verbal behavior to the reliable diagnosis of mild depression, identifying objective signs for distinguishing it from normal sadness; the mood component influenced the whole mental status and was represented in both structure and semantics of patients' speech. The second paper describes the course of panic disorder with agoraphobia, with the notable results that debut of panic disorder with full-blown panic attacks, often declines to a second accompanied with agoraphobia, which after several years gives way to limited symptom attacks and decreased agoraphobic avoidance. The third study describes the high prevalence of affective and anxiety disorders in patients with diabetes mellitus type 1 and 2, and the role of personality traits in adherence to treatment in patients with poor glucose control. The fourth project uses functional MRI for probing the features of neuronal resting-state networks in patients with temporal lobe epilepsy; the association with affective symptoms provides a model for investigating the pathophysiology of mood disorder. PMID:26022056

  8. Copernicus benefits the Norwegian Satellite Earth Observation Database for Marine and Polar Research

    Science.gov (United States)

    Korosov, Anton; Johannessen, Johnny

    2014-05-01

    The Norwegian Satellite Earth Observation Database for Marine and Polar Research (NORMAP) is developed for creating and maintaining a repository of Earth Observation data over the high latitude and Arctic regions to facilitate, stimulate and strengthen high quality and original multidisciplinary Earth System research, application, exploitation and education in marine, polar and climate sciences. As such it is complementing and supporting the Norwegian strategy for advancing these science disciplines in the high latitude and Arctic regions. In the international arena, NORMAP benefits and complements the EU GMES MyOcean project, and other previous GMES downstream services such as AQUAMAR, MONARCH-A, SIDARUS, etc. With the launch of the first Sentinel-1 mission NORMAP will be reinforced by the new data flow from the Copernicus Space Component. NORMAP is also acquiring data from a multitude of other satellites through the unified Copernicus system and will become one of the national thematic information services designed to benefit the environmental monitoring and support effective policy-making.

  9. The Developmental Brain Disorders Database (DBDB): a curated neurogenetics knowledge base with clinical and research applications.

    Science.gov (United States)

    Mirzaa, Ghayda M; Millen, Kathleen J; Barkovich, A James; Dobyns, William B; Paciorkowski, Alex R

    2014-06-01

    The number of single genes associated with neurodevelopmental disorders has increased dramatically over the past decade. The identification of causative genes for these disorders is important to clinical outcome as it allows for accurate assessment of prognosis, genetic counseling, delineation of natural history, inclusion in clinical trials, and in some cases determines therapy. Clinicians face the challenge of correctly identifying neurodevelopmental phenotypes, recognizing syndromes, and prioritizing the best candidate genes for testing. However, there is no central repository of definitions for many phenotypes, leading to errors of diagnosis. Additionally, there is no system of levels of evidence linking genes to phenotypes, making it difficult for clinicians to know which genes are most strongly associated with a given condition. We have developed the Developmental Brain Disorders Database (DBDB: https://www.dbdb.urmc.rochester.edu/home), a publicly available, online-curated repository of genes, phenotypes, and syndromes associated with neurodevelopmental disorders. DBDB contains the first referenced ontology of developmental brain phenotypes, and uses a novel system of levels of evidence for gene-phenotype associations. It is intended to assist clinicians in arriving at the correct diagnosis, select the most appropriate genetic test for that phenotype, and improve the care of patients with developmental brain disorders. For researchers interested in the discovery of novel genes for developmental brain disorders, DBDB provides a well-curated source of important genes against which research sequencing results can be compared. Finally, DBDB allows novel observations about the landscape of the neurogenetics knowledge base.

  10. Collaborative research between academia and industry using a large clinical trial database: a case study in Alzheimer's disease

    DEFF Research Database (Denmark)

    Jones, Roy; Wilkinson, David; Lopez, Oscar L;

    2011-01-01

    Large clinical trials databases, developed over the course of a comprehensive clinical trial programme, represent an invaluable resource for clinical researchers. Data mining projects sponsored by industry that use these databases, however, are often not viewed favourably in the academic medical...... community because of concerns that commercial, rather than scientific, goals are the primary purpose of such endeavours. Thus, there are few examples of sustained collaboration between leading academic clinical researchers and industry professionals in a large-scale data mining project. We present here...

  11. Research and application of ORACLE performance optimizing technologies for building airplane environment resource database

    Science.gov (United States)

    Zhang, Jianjun; Sun, Jianyong; Cheng, Conggao

    2013-03-01

    Many problems exist in processing experimental aircraft vibration (temperature, humidity) data and generating the intermediate calculations during the construction of airplane environment resource database, such as the need to deal with both structural and non-structural data, weak capacity of the client browser for data processing and massive network data transferring etc. To solve the above problems, some strategies on tuning and optimization performance of database are employed base on Oracle11g, which include data storage structure tuning, the memory configuration of the server, the disk I/O tuning and SQL statement tuning. The experimental results show that the performance of airplane environment resource database is enhanced about 80% compared with the database developed in the initial demonstration and validation phase. The application of new optimization strategies to the database construction can lay a sound foundation for finishing building airplane environment resource database.

  12. The research of network database security technology based on web service

    Science.gov (United States)

    Meng, Fanxing; Wen, Xiumei; Gao, Liting; Pang, Hui; Wang, Qinglin

    2013-03-01

    Database technology is one of the most widely applied computer technologies, its security is becoming more and more important. This paper introduced the database security, network database security level, studies the security technology of the network database, analyzes emphatically sub-key encryption algorithm, applies this algorithm into the campus-one-card system successfully. The realization process of the encryption algorithm is discussed, this method is widely used as reference in many fields, particularly in management information system security and e-commerce.

  13. 5-Aminosalicylic acid dependency in Crohn's disease: A Danish Crohn Colitis Database study

    DEFF Research Database (Denmark)

    Duricova, D.; Pedersen, N.; Elkjaer, M.;

    2010-01-01

    Background and aims The role of 5 aminosalicylic acid (5 ASA) in Crohns disease is unclear The outcome of the first course of 5 ASA monotherapy with emphasis on 5 ASA dependency was retrospectively assessed in consecutive cohort of 537 Crohn s disease patients diagnosed 1953-2007 Methods Following...

  14. Database management research for the Human Genome Project. Final progress report for period: 02/01/99 - 06/14/00

    Energy Technology Data Exchange (ETDEWEB)

    Bult, Carol J.

    1999-11-01

    The MouseBLAST server allows researchers to search a sequence within mouse/rodent sequence databases to find matching sequences that may be associated with mouse genes. Query results may be linked to gene detail records in the Mouse Genome Database (MGD). Searches are performed using WU-BLAST 2.0. All sequence databases are updated on a weekly basis.

  15. LLNL Middle East and North Africa and Former Soviet Union Research Database

    Energy Technology Data Exchange (ETDEWEB)

    O' Boyle, J.L.; Ruppert, S.D.; Hauk, T.F.; Dodge, D.; Firpo, M.

    2000-07-14

    The Lawrence Livermore National Laboratory (LLNL) Ground-Based Nuclear Explosion Monitoring (GNEM) R and D program has made significant progress populating a comprehensive Seismic Research knowledge Base (SRKB) and deriving calibration parameters for the Middle East and North Africa (ME/NA) and Former Soviet Union (FSU) regions. The LLNL SRKB provides not only a coherent framework in which to store and organize very large volumes of collected seismic waveforms, associated event parameter information, and spatial contextual data, but also provides an efficient data processing/research environment for deriving location and discrimination correction surfaces. The SRKB is a flexible and extensible framework consisting of a relational database (RDB), Geographical Information System (GIS), and associated product/data visualization and data management tools. This SRKB framework is designed to accommodate large volumes of data (over 2 million waveforms from 20,000 events) in diverse formats from many sources in addition to maintaining detailed quality control and metadata. Using the SRKB framework, they are combining travel-time observations, event characterization studies, and regional tectonic models to assemble a library of ground truth information and phenomenology correction surfaces required for support of the ME/NA and FSU regionalization program. Corrections and parameters distilled from the LLNL SRKB provide needed contributions to the DOE Knowledge Base (DOE KB) for the ME/NA and FSU regions and will help improve monitoring for underground nuclear testing. The LLNL research products will facilitate calibration of IMS stations (primary and auxiliary), their surrogates (if not yet installed) and selected gamma stations necessary to complete the above tasks in the ME/NA and FSU regions. They present expanded lookup tables for critical station parameter information (including location and response) and a new integrated and reconciled event catalog dataset including

  16. FishPathogens.eu a new database in the research of aquatic animal diseases

    DEFF Research Database (Denmark)

    Jonstrup, Søren Peter; Gray, T.; Olesen, Niels Jørgen

    We live in a world where the amount of information available is enormous. In order to keep track of the available knowledge, databases are needed to collect, store, and sort it. Www.fishpathogens.eu is a database developed and maintained by the European Union Reference Laboratory for Fish Diseases....... The database was launched in June 2009 focusing on Viral Haemorrhagic Septicaemia Virus (VHSV), extended with Infectious Haemorrhagic Necrosis Virus (IHNV) in 2010, and is now being extended to include Spring Viraemia of Carp Virus (SVCV), Infectious Salmon Anemia Virus (ISAV), Betanodaviruses, and Koi Herpes...... Virus (KHV). The database design is based on freeware and could easily be implemented to include pathogens relevant for other species than fish. We present the database using the data on the different fish pathogens as example. However if some are interested in the platform we are happy to cooperate...

  17. EST sequences and their annotation (amino acid sequence and results of homology search) - Dicty_cDB | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available and VS) derived from five developmental stages. Clone ID ID of cDNA clone Atlas ID ID of Atlas database ( ht...tp://dictycdb.biol.tsukuba.ac.jp/~tools/bin/ISH/index.html ) and link to Atlas database NBRP ID ID of cDNA c...ir annotations (amino acid sequence, homology search results (with target DBs: dicty EST-DB, DNA-DB and prot...ein-DB)). Links to the Atlas database ( http://dictycdb.biol.tsukuba.ac.jp/~tools/bin/ISH/index.html ), whic

  18. The Method of Analysis Derived Coefficients of Database as a New Method of Historical Research (for Example, a Database of Ballistic Parameters of Naval Artillery

    Directory of Open Access Journals (Sweden)

    Nicholas W. Mitiukov

    2015-12-01

    Full Text Available In paper there is proposed a new method of historical research, based on analysis of derivatives coefficients of database (for example, the form factor in the database of ballistic data. This method has a much greater protection from subjectivism and direct falsification, compared with the analysis obtained directly from the source of the numerical series, as any intentional or unintentional distortion of the raw data provides a significant contrast ratio derived from the average sample values. Application of this method to the analysis of ballistic data base of naval artillery allowed to find the facts, forcing a new look at some of the events in the history data on the German naval artillery before World War I, probably overpriced for disinformation opponents of the Entente; during the First World War, Spain, apparently held secret talks with the firm Bofors ended purchase of Swedish shells; the first Russian naval rifled guns were created obvious based on the project Blackly, not Krupp as traditionally considered.

  19. Development and application of characteristic database for uranium mining and metallurgy in the library of Beijing Research Institute of Chemical Engineering and Metallurgy

    International Nuclear Information System (INIS)

    Beijing Research Institute of Chemical Engineering and Metallurgy (BRICEM) is a multi disciplinary comprehensive research institute engaged in uranium mining, engineering design and related material researches. After 53 years of researches and development, BRICEM has accumulated a plenty of valuable data and resources. By analyzing the actual conditions of BRICEM's technological database, this thesis aims to propose the idea of building a characteristic database for uranium mining and metallurgy. It gives an in-depth analysis on content design, development status and problems of database development, in order to come up with solutions to these problems, as well as suggestions on the future development plans of the characteristic database. (author)

  20. Researches on Cartographic Database-Based Interactive Three-Dimensional Topographic Map

    Institute of Scientific and Technical Information of China (English)

    Jiang Wenping; Xi Daping

    2003-01-01

    With the development of computer graphics, the three-dimensional (3D) visualization brings new technological revolution to the traditional cartography. Therefore, the topographic 3D-map emerges to adapt to this technological revolution, and the applications of topographic 3D-map are spread rapidly to other relevant fields due to its incomparable advantage. The researches on digital map and the construction of map database offer strong technical support and abundant data source for this new technology, so the research and development of topographic 3D-map will receive greater concern. The basic data of the topographic 3D-map are rooted mainly in digital map and its basic model is derived from digital elevation model (DEM) and 3D-models of other DEM-based geographic features. In view of the potential enormous data and the complexity of geographic features, the dynamic representation of geographic information becomes the focus of the research of topographic 3D-map and also the prerequisite condition of 3D query and analysis. In addition to the equipment of hardware that are restraining, to a certain extent, the 3D representation, the data organization structure of geographic information will be the core problem of research on 3D-map. Level of detail (LOD), space partitioning, dynamic object loading (DOL) and object culling are core technologies of the dynamic 3D representation. The objectselection, attribute-query and model-editing are important functions and interaction tools for users with 3D-maps provided by topographic 3D-map system, all of which are based on the data structure of the 3Dmodel. This paper discusses the basic theories, concepts and cardinal principles of topographic 3D-map,expounds the basic way to organize the scene hierarchy of topographic 3D-map based on the node mechanism and studies the dynamic representation technologies of topographic 3D-map based on LOD, space partitioning, DOL and object culling. Moreover, such interactive operation

  1. Asian Agricultural Research is indexed by CABI,CSA Illumina,AGE and other famous databases in many countries

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers, Asian Agricultural Research eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as one of the most author-itative and prestigious abstract data bases concerning agriculture and forestry. Since inception of publication, Asian Agri-cultural Research has also been indexed by AGE Database, Naresuan University Library, Rural Development Foundation of India, Royal Tropical Institute and CSA Illumina.

  2. Asian Agricultural Research is indexed by CABI, CSA Illumina, AGE and other famous databases in many countries

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers, Asian Agricultural Research eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as one of the most authoritative and prestigious abstract data bases concerning agriculture and forestry. Since inception of publication, Asian Agricultural Research has also been indexed by AGE Database, Naresuan University Library, Rural Development Foundation of India, Royal Tropical Institute and CSA lllumina.

  3. The Nordic prescription databases as a resource for pharmacoepidemiological research-a literature review

    DEFF Research Database (Denmark)

    Wettermark, Bjørn; Wallach-Kildemoes, Helle

    2013-01-01

    these databases. METHODS: The study consists of a Medline-based structured literature review of scientific papers published during 2005-2010 using data from the prescription databases in Denmark, Finland, Iceland, Norway, and Sweden, covering 25 million inhabitants. Relevant studies were analyzed in terms......PURPOSE: All five Nordic countries have nationwide prescription databases covering all dispensed drugs, with potential for linkage to outcomes. The aim of this review is to present an overview of therapeutic areas studied and methods applied in pharmacoepidemiologic studies using data from...

  4. Recent Progress on Selected Topics in Database Research--A Report by Nine Young Chinese Researchers Working in the United States

    Institute of Scientific and Technical Information of China (English)

    Zhiyuan Chen; Chen Li; Jian Pei; Yufei Tao; Haixun Wang; Wei Wang; Jiong Yang; Jun Yang; Donghui Zhang

    2003-01-01

    The study on database technologies, or more generally, the technologies of dataand information management, is an important and active research field. Recently, many excitingresults have been reported. In this fast growing field, Chinese researchers play more and more activeroles. Research papers from Chinese scholars, both in China and abroad, appear in prestigious academic forums.In this paper, we, nine young Chinese researchers working in the United States, presentconcise surveys and report our recent progress on the selected fields that we are working on.Although the paper covers only a small number of topics and the selection of the topics is far frombalanced, we hope that such an effort would attract more and more researchers, especially thosein China, to enter the frontiers of database research and promote collaborations. For the obviousreason, the authors are listed alphabetically, while the sections are arranged in the order of theauthor list.

  5. MEDIANOVO - a media database for medical education, research and health care.

    Science.gov (United States)

    Wunderlich, M; Ott, A; Bernauer, J; Leichsenring, M

    2003-01-01

    MEDIANOVO provides a high quality, scientifically indexed multi-media database with comfortable authoring and download functions through a web-based frontend. Currently, MEDIANOVO is used by medical teachers as a repository for storing and sharing media for educational purposes. However a database was created which could also serve with training and further education, in computer based learning systems as well as medical publishers and for individual patient information. Through the web-frontend the content is available worldwide. PMID:14728583

  6. Nucleic Acid Aptamers: Research Tools in Disease Diagnostics and Therapeutics

    OpenAIRE

    Baby Santosh; Pramod K. Yadava

    2014-01-01

    Aptamers are short sequences of nucleic acid (DNA or RNA) or peptide molecules which adopt a conformation and bind cognate ligands with high affinity and specificity in a manner akin to antibody-antigen interactions. It has been globally acknowledged that aptamers promise a plethora of diagnostic and therapeutic applications. Although use of nucleic acid aptamers as targeted therapeutics or mediators of targeted drug delivery is a relatively new avenue of research, one aptamer-based drug “Ma...

  7. Research on Activators for Lead-Acid Batteries

    OpenAIRE

    Sugawara, Michio; Kozawa, Akiya

    2008-01-01

    Abstract : The ITE Battery Research group has developed a new organic battery activator for new and used lead-acid batteries. Ten years of investigation have established the validity of the ITE activator that prolongs the useful life of lead-acid batteries. It has been shown that the specific gravity of spent batteries can be restored to the original level in automotive, motive power; uninterruptible power supplies (UPS) and stationary energy storage batteries. Our results show that the disca...

  8. Development of a Cost-Effective Database Software for Psychiatric Research: A Study From Tertiary Care Teaching Hospital

    Directory of Open Access Journals (Sweden)

    Sabu Karakkamandapam

    2010-10-01

    Full Text Available Background: Technological progression made drastic changes in health care. Still there is a growing concern about proper utilization of health information within hospitals for various research activities. Huge volumes of such health information in majority of hospitals are redundant due to lack of appropriate and cost-effective technological tools for retrieving relevant health information for research purpose. Objective: To develop a cost-effective and user-friendly computerized medical record database for psychiatry using available technology with the department. Methodology: Study performed at a tertiary care teaching hospital in Udupi district of South India. Various datasets from psychiatry medical records were utilized for the design and creation of database. A computerized database called PsyCase was developed with the help of technology available within the department. A 4612 patient’s data were entered into the PsyCase and subjected to various analyses. Results: Applications of PsyCase in various epidemiological studies were explored through performing numerous analyses with actual data. PsyCase was found effective in supporting psychiatric research as well as routine clinical and administrative activities. Conclusion: This study emphasizes need of appropriate use of technology available within a healthcare system to facilitate medical research in psychiatry and role of health information professional in such initiatives. Healthcare organization must focus on collective utilization of resources within the system to improve the utilization of health information for medical research.

  9. 高校科研管理系统数据库设计与实现%Design and Realization of University Scientific Research Management System Database

    Institute of Scientific and Technical Information of China (English)

    李海生; 李春青

    2014-01-01

    数据库设计是科研管理系统设计的核心,该文从数据库表的创建、SQL Server数据库关键技术的应用、数据库用户安全性管理、ADO.NET数据库访问技术和SQL Server数据库连接5个方面阐述高校科研管理系统数据库的设计与实现。%The database design is the core of the scientific research management system design, this article from the establishment of database tables, SQL Server database key technology application, the database user security management, ADO.NET database access technology and SQL Server database connection with the 5 aspects of the university scientific research management system design and implementation of the database.

  10. ATGC: a database of orthologous genes from closely related prokaryotic genomes and a research platform for microevolution of prokaryotes

    Energy Technology Data Exchange (ETDEWEB)

    Novichkov, Pavel S.; Ratnere, Igor; Wolf, Yuri I.; Koonin, Eugene V.; Dubchak, Inna

    2009-07-23

    The database of Alignable Tight Genomic Clusters (ATGCs) consists of closely related genomes of archaea and bacteria, and is a resource for research into prokaryotic microevolution. Construction of a data set with appropriate characteristics is a major hurdle for this type of studies. With the current rate of genome sequencing, it is difficult to follow the progress of the field and to determine which of the available genome sets meet the requirements of a given research project, in particular, with respect to the minimum and maximum levels of similarity between the included genomes. Additionally, extraction of specific content, such as genomic alignments or families of orthologs, from a selected set of genomes is a complicated and time-consuming process. The database addresses these problems by providing an intuitive and efficient web interface to browse precomputed ATGCs, select appropriate ones and access ATGC-derived data such as multiple alignments of orthologous proteins, matrices of pairwise intergenomic distances based on genome-wide analysis of synonymous and nonsynonymous substitution rates and others. The ATGC database will be regularly updated following new releases of the NCBI RefSeq. The database is hosted by the Genomics Division at Lawrence Berkeley National laboratory and is publicly available at http://atgc.lbl.gov.

  11. THE BUILDING OF THE SPATIAL DATABASE OF THE SATCHINEZ ORNITHOLOGICAL RESERVE AS A PREMISE OF MODERN ECOLOGICAL RESEARCH

    Directory of Open Access Journals (Sweden)

    M. Török-Oance

    2005-01-01

    Full Text Available The creation of a database for the Ornithological Reserve “The Satchinez Marshes” was a necessity for a modern and complex ecological research. This database offers the possibility of a precise localization of the species of plants and animals identified in the field and it is a genuine base for the identification of the main types of habitats and ecosystems in the reserve. With the help of the Terrain Numerical Model, the analysis, at the level of pixels, of the abiotical factors involved in the repartition of ecosystems was made possible, as well as the three-dimensions visualizations of all the results. With the help of the aerophotograms taken in 1963 and 1973, we reconstructed the situation of the reserve at that time, by creating a database of the terrain usage at that time. The same thing was done in 2004, using more diverse sources: cadastral planes, images taken from the satellite, air photos taken in the same year and last, but not least, data collected in the field in 2003-2004. At the same time, this database can be considered a bench-mark (for the year 2004 for the identification of the modifications that occurred during 1963 and 2004, but for future research as well.

  12. RESEARCH ON HLR MOBILITY DATABASE FAILURE RECOVERY AND PERFORMANCE ANALYSIS FOR CDMA2000 SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    Liu Caixia; Yu Dingjiu; Cheng Dongnian; Tang Hongbo; Wu Jiangxing

    2004-01-01

    In this paper, a novel Home Location Register(HLR) mobility database recovery scheme is proposed. With database backing-up and signal sending as its key processes, the presented scheme is designed for the purpose of both decreasing system costs and reducing number of lost calls. In our scheme, an algorithm is developed for an HLR to identify such VLRs that there are new MSs roaming into them since the latest HLR database backing up. The identification of those VLRs is used by the HLR to send Unreliable Roaming Data Directive messages to each of them to get the correct location information of those new MSs. Additionally, two kinds of relationships, one between the number of lost calls and the database backing-up period and the other between the backing-up cost and the period, are well analyzed. Both analytical and numerical results indicate that there will be an optimal HLR database backing-up period if certain system parameters are given and the total cost can be consequently minimized.

  13. The Aspergillus Genome Database, a curated comparative genomics resource for gene, protein and sequence information for the Aspergillus research community.

    Science.gov (United States)

    Arnaud, Martha B; Chibucos, Marcus C; Costanzo, Maria C; Crabtree, Jonathan; Inglis, Diane O; Lotia, Adil; Orvis, Joshua; Shah, Prachi; Skrzypek, Marek S; Binkley, Gail; Miyasato, Stuart R; Wortman, Jennifer R; Sherlock, Gavin

    2010-01-01

    The Aspergillus Genome Database (AspGD) is an online genomics resource for researchers studying the genetics and molecular biology of the Aspergilli. AspGD combines high-quality manual curation of the experimental scientific literature examining the genetics and molecular biology of Aspergilli, cutting-edge comparative genomics approaches to iteratively refine and improve structural gene annotations across multiple Aspergillus species, and web-based research tools for accessing and exploring the data. All of these data are freely available at http://www.aspgd.org. We welcome feedback from users and the research community at aspergillus-curator@genome.stanford.edu.

  14. Oracle数据库死锁问题研究%Research on Deadlock of Oracle Database

    Institute of Scientific and Technical Information of China (English)

    姜文; 刘立康

    2014-01-01

    数据库是网络环境下多用户使用的共享资源,数据库在处理多线程大量数据存取过程中很可能出现死锁现象。文中介绍了Oracle数据库锁机制和死锁发生的原因,Oracle数据库检测死锁采用的相关视图。详细叙述了SQL语句检测死锁、死锁的定位方法和解决数据库死锁的方法。编写了在Linux环境中死锁检测脚本,模拟Oracle数据库死锁测试了脚本的正确性。实际应用表明该方法可以有效监测程序中的主要模块是否发生死锁,而且简单有效。%The database is a shared resource of multi-user in network environment,database deadlock phenomenon is likely to occur in multi-threaded process by large amounts of data access. Introduce the Oracle database locking mechanism and the causes the deadlock oc-curs,the Oracle database detects the related views deadlock uses. A detailed description is conducted for the SQL states the deadlock de-tection,the positioning method of deadlock and the resolution of the database deadlock. Compiled the deadlock detection script in the Linux environment,simulate the Oracle database deadlock to test the correctness of the script. Practical application shows that the script can be effective monitoring whether the program's main module is deadlock or not,with simplicity and effectiveness.

  15. Research on Optimization of Oracle Database%Oracle数据库系统优化调整

    Institute of Scientific and Technical Information of China (English)

    刘超; 张明安

    2014-01-01

    在过去的几十年中,OracIe 数据库已经逐渐成为世界上最为广泛的大型数据库管理系统。而数据库 DBA的重要工作就是要确保利用 OracIe 的强大特性来提高企业的生产力。其中最有效的方法就是通过 OracIe 调优,它有大量的调整参数和技术来改进 OracIe 数据库的性能。文章从数据库内存参数调整、索引技术、数据库分区以及SQL 语句的优化等四个方面来研究 OracIe 数据库的性能调整。%In the past few decades, Oracle database has become the world's large database management system. The important work of DBA is to ensure that the use of the powerful features of Oracle and improve their productivity. One of the most ef ective ways is through the Oracle tuning. Certainly, the performance of Oracle database can be improved through a large number of parameters and technology. The article explains the things from Database memory parameter adjustment,index technology,database partition, and SQL statement optimization etc onthe performance optimization of Oracle database.

  16. SU-E-P-26: Oncospace: A Shared Radiation Oncology Database System Designed for Personalized Medicine, Decision Support, and Research

    International Nuclear Information System (INIS)

    Purpose: Advancement in Radiation Oncology (RO) practice develops through evidence based medicine and clinical trial. Knowledge usable for treatment planning, decision support and research is contained in our clinical data, stored in an Oncospace database. This data store and the tools for populating and analyzing it are compatible with standard RO practice and are shared with collaborating institutions. The question is - what protocol for system development and data sharing within an Oncospace Consortium? We focus our example on the technology and data meaning necessary to share across the Consortium. Methods: Oncospace consists of a database schema, planning and outcome data import and web based analysis tools.1) Database: The Consortium implements a federated data store; each member collects and maintains its own data within an Oncospace schema. For privacy, PHI is contained within a single table, accessible to the database owner.2) Import: Spatial dose data from treatment plans (Pinnacle or DICOM) is imported via Oncolink. Treatment outcomes are imported from an OIS (MOSAIQ).3) Analysis: JHU has built a number of webpages to answer analysis questions. Oncospace data can also be analyzed via MATLAB or SAS queries.These materials are available to Consortium members, who contribute enhancements and improvements. Results: 1) The Oncospace Consortium now consists of RO centers at JHU, UVA, UW and the University of Toronto. These members have successfully installed and populated Oncospace databases with over 1000 patients collectively.2) Members contributing code and getting updates via SVN repository. Errors are reported and tracked via Redmine. Teleconferences include strategizing design and code reviews.3) Successfully remotely queried federated databases to combine multiple institutions’ DVH data for dose-toxicity analysis (see below – data combined from JHU and UW Oncospace). Conclusion: RO data sharing can and has been effected according to the Oncospace

  17. SU-E-P-26: Oncospace: A Shared Radiation Oncology Database System Designed for Personalized Medicine, Decision Support, and Research

    Energy Technology Data Exchange (ETDEWEB)

    Bowers, M; Robertson, S; Moore, J; Wong, J; DeWeese, T; McNutt, T [Johns Hopkins University, Baltimore, MD (United States); Phillips, M [Univ Washington, Seattle, WA (United States); Hendrickson, K [University of Washington, Seattle, WA (United States); Song, W; Kwok, P [Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, U of T, Toronto, Ontario (Canada)

    2015-06-15

    Purpose: Advancement in Radiation Oncology (RO) practice develops through evidence based medicine and clinical trial. Knowledge usable for treatment planning, decision support and research is contained in our clinical data, stored in an Oncospace database. This data store and the tools for populating and analyzing it are compatible with standard RO practice and are shared with collaborating institutions. The question is - what protocol for system development and data sharing within an Oncospace Consortium? We focus our example on the technology and data meaning necessary to share across the Consortium. Methods: Oncospace consists of a database schema, planning and outcome data import and web based analysis tools.1) Database: The Consortium implements a federated data store; each member collects and maintains its own data within an Oncospace schema. For privacy, PHI is contained within a single table, accessible to the database owner.2) Import: Spatial dose data from treatment plans (Pinnacle or DICOM) is imported via Oncolink. Treatment outcomes are imported from an OIS (MOSAIQ).3) Analysis: JHU has built a number of webpages to answer analysis questions. Oncospace data can also be analyzed via MATLAB or SAS queries.These materials are available to Consortium members, who contribute enhancements and improvements. Results: 1) The Oncospace Consortium now consists of RO centers at JHU, UVA, UW and the University of Toronto. These members have successfully installed and populated Oncospace databases with over 1000 patients collectively.2) Members contributing code and getting updates via SVN repository. Errors are reported and tracked via Redmine. Teleconferences include strategizing design and code reviews.3) Successfully remotely queried federated databases to combine multiple institutions’ DVH data for dose-toxicity analysis (see below – data combined from JHU and UW Oncospace). Conclusion: RO data sharing can and has been effected according to the Oncospace

  18. Active Databases & Their Research Status%主动数据库及其研究现状

    Institute of Scientific and Technical Information of China (English)

    梁雯

    2001-01-01

    The similarities and differences between an active database and a traditional database are expounded. The general model of an active database and the model of the Active Database Management System are discussed. In the light of the deficiencies of the object-oriented database, the paper probes into the superiorities of combining the active database with the object-oriented database. It also discusses the present situation and the development of the active database as well as the problems to be solved.

  19. Patient-related risk factors for fracture-healing complications in the United Kingdom General Practice Research Database

    OpenAIRE

    HERNANDEZ, ROHINI K.; Do, Thy P.; Critchlow, Cathy W; Dent, Ricardo E.; Jick, Susan S

    2012-01-01

    Background and purpose A variety of risk factors have been hypothesized to contribute to the development of fracture-healing complications; however, population-based estimates of the strength of these risk factors are limited. In this case-control study, we evaluated patient-related risk factors for fracture-healing complications. Methods Using the United Kingdom General Practice Research Database, we identified patients with a fracture-healing complication (delayed union, nonunion, or maluni...

  20. Scientometric dimensions of nuclear science and technology research in India : a study based on INIS (1970-2002) database

    OpenAIRE

    Kademani, B. S.; Vijai, Kumar; Anil, Sagar; Anil, Kumar

    2006-01-01

    This paper attempts to analyse quantitatively the growth and development of Nuclear Science and Technology research in India in terms of publication output as reflected in International Nuclear Information System (INIS) (1970-2002) database. During 1970-2002 a total of 55313 papers were published by the Indian Nuclear scientists to various domains : Physics (23033), Chemistry (16368),Life and Environmental Sciences (7203) Engineering and Technology ( 6960), Other Aspects of Nuclear and Non Nu...

  1. Historical land use databases: a new layer of information for geographical research

    NARCIS (Netherlands)

    Kramer, H.; Mücher, C.A.; Hazeu, G.W.

    2011-01-01

    In this paper we describe how historical land use information has been derived for the whole of Europe, using the World Atlas of Agriculture, scale 1: 2,500,000. This paper describes the process of converting the analog land-use maps to a digital European historical land-use database, the Historical

  2. D Digital Model Database Applied to Conservation and Research of Wooden Construction in China

    Science.gov (United States)

    Zheng, Y.

    2013-07-01

    Protected by the Tai-Hang Mountains, Shanxi Province, located in north central China, is a highly prosperous, densely populated valley and considered to be one of the cradles of Chinese civilization. Its continuous habitation and rich culture have given rise to a large number of temple complexes and pavilions. Among these structures, 153 can be dated as early as from the Tang dynasty (618- 907C.E.) to the end of the Yuan dynasty (1279-1368C.E.) in Southern Shanxi area. The buildings are the best-preserved examples of wooden Chinese architecture in existence, exemplifying historic building technology and displaying highly intricate architectural decoration and detailing. They have survived war, earthquakes, and, in the last hundred years, neglect. In 2005, a decade-long conservation project was initiated by the State Administration of Cultural Heritage of China (SACH) to conserve and document these important buildings. The conservation process requires stabilization, conservation of important features, and, where necessary, partial dismantlement in order to replace unsound structural elements. Project team of CHCC have developed a practical recording system that created a record of all building components prior to and during the conservation process. After that we are trying to establish a comprehensive database which include all of the 153 earlier buildings, through which we can easily entering, browse, indexing information of the wooden construction, even deep into component details. The Database can help us to carry out comparative studies of these wooden structures, and, provide important support for the continued conservation of these heritage buildings. For some of the most important wooden structure, we have established three-dimensional models. Connected the Database with 3D Digital Model based on ArcGIS, we have developed 3D Digital Model Database for these cherish buildings. The 3D Digital Model Database helps us set up an integrate information inventory

  3. 动态WEB数据库应用探究%Application Research of dynamic WEB database

    Institute of Scientific and Technical Information of China (English)

    乔立龙

    2015-01-01

    数据库技术现在已经相对成熟,并且结构比较严谨,不过这个灵活度还不够,如果可以实现把数据库和web相结合,那么必定能够在很大程度上扩大数据库的一个应用领域,这个相结合的方式其实也是现在数据库技术研究的一个热点。本课题总介绍的动态WEB数据库技术是采用这个中间件来完成的,这个的一个实现方法是:使用中间件吧这个Web服务器还有数据库服务器连在一个。由于中间件不当当可以使得前端用户能够访问后端异构数据库的这个数据源而达到一个中间件透明化的效果,同时还能够确保存取访问接口的一个开放性。%Database technology is already mature,and more rigorous structure,but this flexibility is not enough,if can realize the combination of database and web,then will be able to expand the database in a large extent of an applied field,the combination of in fact,is now the database technology a hot. This topic describes the dynamic web database technology is using the middleware to accomplish,this a realization method is that using middleware it the web server and database server connected to a.Due to the middleware Dangdang can make the front-end user to access heterogeneous backend database with the data source to a middleware transparency effect,but also can ensure the access interface of an open.

  4. Geoscientific (GEO) database of the Andra Meuse / Haute-Marne research center

    International Nuclear Information System (INIS)

    Document available in extended abstract form only. The GEO database (geo-scientific database of the Meuse/Haute-Marne Center) is a tool developed by Andra, with a view to group in a secured computer form all data related to the acquisition of in situ and laboratory measurements made on solid and fluid samples. This database has three main functions: - Acquisition and management of data and computer files related to geological, geomechanical, hydrogeological and geochemical measurements on solid and fluid samples and in situ measurements (logging, on sample measurements, geological logs, etc). - Available consultation by the staff on Andra's intranet network for selective viewing of data linked to a borehole and/or a sample and for making computations and graphs on sets of laboratory measurements related to a sample. - Physical management of fluid and solid samples stored in a 'core library' in order to localize a sample, follow-up its movement out of the 'core library' to an organization, and carry out regular inventories. The GEO database is a relational Oracle data base. It is installed on a data server which stores information and manages the users' transactions. The users can consult, download and exploit data from any computer connected to the Andra network or Internet. Management of the access rights is made through a login/ password. Four geo-scientific explanations are linked to the Geo database, they are: - The Geosciences portal: The Geosciences portal is a web Intranet application accessible from the ANDRA network. It does not require a particular installation from the client and is accessible through the Internet navigator. A SQL Server Express database manages the users and access rights to the application. This application is used for the acquisition of hydrogeological and geochemical data collected on the field and on fluid samples, as well as data related to scientific work carried out at surface level or in drifts

  5. A plant resource and experiment management system based on the Golm Plant Database as a basic tool for omics research

    Directory of Open Access Journals (Sweden)

    Selbig Joachim

    2008-05-01

    names generated by the system and barcode labels facilitate identification and management of the material. Web pages are provided as user interfaces to facilitate maintaining the system in an environment with many desktop computers and a rapidly changing user community. Web based search tools are the basis for joint use of the material by all researchers of the institute. Conclusion The Golm Plant Database system, which is based on a relational database, collects the genetic and environmental information on plant material during its production or experimental use at the Max-Planck-Institute of Molecular Plant Physiology. It thus provides information according to the MIAME standard for the component 'Sample' in a highly standardised format. The Plant Database system thus facilitates collaborative work and allows efficient queries in data analysis for systems biology research.

  6. Oracle数据库应用中安全问题研究%Research Oracle Database Application Security Issues

    Institute of Scientific and Technical Information of China (English)

    姚树春

    2014-01-01

    The Oracle database is the most direct way for enterprises to share resources, and its own security has also become the focus of one of the elements considered in today's enterprise. Although database systems bring people in dealing with the many convenient data problems, but also to the system brought a lot of security risks, in order to ensure reliable and secure database management system to ensure safety in the application of this paper, the Oracle database application security issues make research initiatives.%Oracle数据库的建立是企业实现资源共享的最直接途径,其自身的安全性也成为现今企业重点考虑的要素之一。尽管数据库系统带给了人们在处理数据问题上的诸多便利,但同时也给系统带来了诸多安全隐患,为保证数据库系统管理的安全可靠、确保在应用方面的安全性,本文就Oracle数据库应用中安全问题的举措做出研究。

  7. Development of a database for prompt γ-ray neutron activation analysis. Summary report of the first research coordination meeting

    International Nuclear Information System (INIS)

    This report summarizes the presentations, recommendations and conclusions of the First Research Co-ordination Meeting on Development of a Database for Prompt γ-ray Neutron Activation Analysis. Neutron-capture Prompt γ-ray Activation Analysis (PGAA) is a non-destructive radioanalytical method, capable of rapid or in-situ simultaneous multielement analysis of many elements of the Periodic Table, from hydrogen to uranium, in the same sample. Inaccuracy and incompleteness of the data available for use in PGAA are a significant handicap in the qualitative and quantitative analysis of capture-gamma spectra. The goal of this CRP is to replace the twenty-year-old data from a single laboratory with something fundamentally new: an evaluated database which includes a combination of evaluated nuclear physics data, physical theory, and recent measurements. The resulting database will be comparable in quality with that for radioactive decay. In addition, more accurate values of neutron capture cross-sections and γ-ray intensities that result from this database will improve the accuracy of radiation shielding calculations. (author)

  8. KALIMER database development

    International Nuclear Information System (INIS)

    KALIMER database is an advanced database to utilize the integration management for liquid metal reactor design technology development using Web applications. KALIMER design database is composed of results database, Inter-Office Communication (IOC), 3D CAD database, and reserved documents database. Results database is a research results database during all phase for liquid metal reactor design technology development of mid-term and long-term nuclear R and D. IOC is a linkage control system inter sub project to share and integrate the research results for KALIMER. 3D CAD database is a schematic overview for KALIMER design structure. And reserved documents database is developed to manage several documents and reports since project accomplishment

  9. KALIMER database development

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Kwan Seong; Lee, Yong Bum; Jeong, Hae Yong; Ha, Kwi Seok

    2003-03-01

    KALIMER database is an advanced database to utilize the integration management for liquid metal reactor design technology development using Web applications. KALIMER design database is composed of results database, Inter-Office Communication (IOC), 3D CAD database, and reserved documents database. Results database is a research results database during all phase for liquid metal reactor design technology development of mid-term and long-term nuclear R and D. IOC is a linkage control system inter sub project to share and integrate the research results for KALIMER. 3D CAD database is a schematic overview for KALIMER design structure. And reserved documents database is developed to manage several documents and reports since project accomplishment.

  10. Establishment of database and network for research of stream generator and state of the art technology review

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Jae Bong; Hur, Nam Su; Moon, Seong In; Seo, Hyeong Won; Park, Bo Kyu; Park, Sung Ho; Kim, Hyung Geun [Sungkyunkwan Univ., Seoul (Korea, Republic of)

    2004-02-15

    A significant number of steam generator tubes are defective and are removed from service or repaired world widely. This wide spread damage has been caused by diverse degradation mechanisms, some of which are difficult to detect and predict. Regarding domestic nuclear power plants, also, the increase of number of operating nuclear power plants and operating periods may result in the increase of steam generator tube failure. So, it is important to carry out the integrity evaluation process to prevent the steam generator tube damage. There are two objectives of this research. The one is to make database for the research of steam generator at domestic research institution. It will increase the efficiency and capability of limited domestic research resources by sharing data and information through network organization. Also, it will enhance the current standard of integrity evaluation procedure that is considerably conservative but can be more reasonable. The second objective is to establish the standard integrity evaluation procedure for steam generator tube by reviewing state of the art technology. The research resources related to steam generator tubes are managed by the established web-based database system. The following topics are covered in this project: development of web-based network for research on steam generator tubes review of state of the art technology.

  11. Biological Databases

    Directory of Open Access Journals (Sweden)

    Kaviena Baskaran

    2013-12-01

    Full Text Available Biology has entered a new era in distributing information based on database and this collection of database become primary in publishing information. This data publishing is done through Internet Gopher where information resources easy and affordable offered by powerful research tools. The more important thing now is the development of high quality and professionally operated electronic data publishing sites. To enhance the service and appropriate editorial and policies for electronic data publishing has been established and editors of article shoulder the responsibility.

  12. [Advances in the research of treatment of hydrofluoric acid burn].

    Science.gov (United States)

    Wang, Xin-gang; Zhang, Yuan-hai; Han, Chun-mao

    2013-08-01

    Hydrofluoric acid (HF) is one of the most common inorganic acids used widely in industrial circle. HF not only causes cutaneous burn, but also induces systemic toxicity by its unique injury mechanism. Accurate and timely diagnosis and treatment are critical after HF burns. To date, the strategies for treating HF burns have been developed, mainly including topical treatments and systematic support. However, there is no standard treatment strategy with wide acceptance in the world. This paper presents a comprehensive overview of the advances in the research of strategies for the treatment of HF burns.

  13. The Human Studies Database Project: Federating Human Studies Design Data Using the Ontology of Clinical Research

    OpenAIRE

    Sim, Ida; Carini, Simona; Tu, Samson; Wynden, Rob; Pollock, Brad H.; Mollah, Shamim A.; Gabriel, Davera; Hagler, Herbert K.; Scheuermann, Richard H.; Lehmann, Harold P.; Wittkowski, Knut M.; Nahm, Meredith; Bakken, Suzanne

    2010-01-01

    Human studies, encompassing interventional and observational studies, are the most important source of evidence for advancing our understanding of health, disease, and treatment options. To promote discovery, the design and results of these studies should be made machine-readable for large-scale data mining, synthesis, and re-analysis. The Human Studies Database Project aims to define and implement an informatics infrastructure for institutions to share the design of their human studies. We h...

  14. PGSB PlantsDB: updates to the database framework for comparative plant genome research

    OpenAIRE

    Spannagl, Manuel; Nussbaumer, Thomas; Bader, Kai C.; Martis, Mihaela-Maria; Seidel, Michael; Kugler, Karl G; Gundlach, Heidrun; Mayer, Klaus F. X.

    2016-01-01

    PGSB (Plant Genome and Systems Biology: formerly MIPS) PlantsDB (http://pgsb.helmholtz-muenchen.de/plant/index.jsp) is a database framework for the comparative analysis and visualization of plant genome data. The resource has been updated with new data sets and types as well as specialized tools and interfaces to address user demands for intuitive access to complex plant genome data. In its latest incarnation, we have re-worked both the layout and navigation structure and implemented new keyw...

  15. Mapping the Iranian Research Literature in the Field of Traditional Medicine in Scopus Database 2010-2014

    Science.gov (United States)

    GhaedAmini, Hossein; Okhovati, Maryam; Zare, Morteza; Saghafi, Zahra; Bazrafshan, Azam; GhaedAmini, Alireza; GhaedAmini, Mohammadreza

    2016-01-01

    Background: The aim of this study was to provide research and collaboration overview of Iranian research efforts in the field of traditional medicine during 2010-2014. Methods: This is a bibliometric study using the Scopus database as data source, using search affiliation address relevant to traditional medicine and Iran as the search strategy. Subject and geographical overlay maps were also applied to visualize the network activities of the Iranian authors. Highly cited articles (citations >10) were further explored to highlight the impact of research domains more specifically. Results: About 3,683 articles were published by Iranian authors in Scopus database. The compound annual growth rate of Iranian publications was 0.14% during 2010-2014. Tehran University of Medical Sciences (932 articles), Shiraz University of Medical Sciences (404 articles) and Tabriz Islamic Medical University (391 articles), were the leading institutions in the field of traditional medicine. Medicinal plants (72%), digestive system’s disease (21%), basics of traditional medicine (13%), mental disorders (8%) were the major research topics. United States (7%), Netherlands (3%), and Canada (2.6%) were the most important collaborators of Iranian authors. Conclusion: Iranian research efforts in the field of traditional medicine have been increased slightly over the last years. Yet, joint multi-disciplinary collaborations are needed to cover inadequately described areas of traditional medicine in the country.

  16. Oracle Database Security Research%Oracle数据库安全性分析研究

    Institute of Scientific and Technical Information of China (English)

    胡歆

    2012-01-01

    随着计算机网络的发展,数据的共享日益加强,数据的安全保密越来越重要。为了响应数据安全需求,Oracle在其数据库产品中实现了强大的安全特性。文章从数据库用户安全、权限设置、数据限制等几个方面对Oracle数据库的安全性能进行分析研究。%With the development of computer network,data sharing is strengthened increasingly,data security is becoming more and more important.In response to the data security requirements,Oracle in its database product to achieve a strong security features.This article from the database user permissions settings,security,data on several aspects such as the Oracle database security performance analysis.

  17. Data Mining in Distributed Database of the First Egyptian Thermal Research Reactor (ETRR-1)

    International Nuclear Information System (INIS)

    Distributed database (DDB)technology application systems are growing up to cover many fields an domains, and at different levels. the aim of this paper is to shade some lights on applying the new technology of distributed database on the ETRR-1 operation data logged by the data acquisition system (DACQUS)and one can extract a useful knowledge. data mining with scientific methods and specialize tools is used to support the extraction of useful knowledge from the rapidly growing volumes of data . there are many shapes and forms for data mining methods. predictive methods furnish models capable of anticipating the future behavior of quantitative or qualitative database variables. when the relationship between the dependent an independent variables is nearly liner, linear regression method is the appropriate data mining strategy. so, multiple linear regression models have been applied to a set of data samples of the ETRR-1 operation data, using least square method. the results show an accurate analysis of the multiple linear regression models as applied to the ETRR-1 operation data

  18. Creating a data exchange strategy for radiotherapy research: Towards federated databases and anonymised public datasets

    NARCIS (Netherlands)

    Skripcak, T.; Belka, C.; Bosch, W.; Brink, C. Van den; Brunner, T.; Budach, V.; Büttner, D.; Debus, J.; Dekker, A.; Grau, C.; Gulliford, S.; Hurkmans, C.; Just, U.; Krause, M.; Lambin, P.; Langendijk, J.A.; Lewensohn, R.; Luhr, A.; Maingon, P.; Masucci, M.; Niyazi, M.; Poortmans, P.M.P.; Simon, M.; Schmidberger, H.; Spezi, E.; Stuschke, M.; Valentini, V.; Verheij, M.; Whitfield, G.; Zackrisson, B.; Zips, D.; Baumann, M.

    2014-01-01

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research

  19. Creating a data exchange strategy for radiotherapy research : Towards federated databases and anonymised public datasets

    NARCIS (Netherlands)

    Skripcak, Tomas; Belka, Claus; Bosch, Walter; Brink, Carsten; Brunner, Thomas; Budach, Volker; Buettner, Daniel; Debus, Juergen; Dekker, Andre; Grau, Cai; Gulliford, Sarah; Hurkmans, Coen; Just, Uwe; Krause, Mechthild; Lambin, Philippe; Langendijk, Johannes A.; Lewensohn, Rolf; Luehr, Armin; Maingon, Philippe; Masucci, Michele; Niyazi, Maximilian; Poortmans, Philip; Simon, Monique; Schmidberger, Heinz; Spezi, Emiliano; Stuschke, Martin; Valentini, Vincenzo; Verheij, Marcel; Whitfield, Gillian; Zackrisson, Bjoern; Zips, Daniel; Baumann, Michael

    2014-01-01

    Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate 'translational research

  20. Database Urban Europe

    NARCIS (Netherlands)

    Sleutjes, B.; de Valk, H.A.G.

    2016-01-01

    Database Urban Europe: ResSegr database on segregation in The Netherlands. Collaborative research on residential segregation in Europe 2014–2016 funded by JPI Urban Europe (Joint Programming Initiative Urban Europe).

  1. The Energy Science and Technology Database on a local library system: A case study at the Los Alamos National Research Library

    Energy Technology Data Exchange (ETDEWEB)

    Holtkamp, I.S.

    1994-10-01

    This paper presents an overview of efforts at Los Alamos National Laboratory to acquire and mount the Energy Science and Technology Database (EDB) as a citation database on the Research Library`s Geac Advance system. The rationale for undertaking this project and expected benefits are explained. Significant issues explored are loading non-USMARC records into a MARC-based library system, the use of EDB records to replace or supplement in-house cataloging of technical reports, the impact of different cataloging standards and database size on searching and retrieval, and how integrating an external database into the library`s online catalog may affect staffing and workflow.

  2. DMPD: Plasmacytoid dendritic cells: sensing nucleic acids in viral infection andautoimmune diseases. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 18641647 Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and... (.csml) Show Plasmacytoid dendritic cells: sensing nucleic acids in viral infection andautoimmune diseases.... PubmedID 18641647 Title Plasmacytoid dendritic cells: sensing nucleic acids in v

  3. PGSB PlantsDB: updates to the database framework for comparative plant genome research.

    Science.gov (United States)

    Spannagl, Manuel; Nussbaumer, Thomas; Bader, Kai C; Martis, Mihaela M; Seidel, Michael; Kugler, Karl G; Gundlach, Heidrun; Mayer, Klaus F X

    2016-01-01

    PGSB (Plant Genome and Systems Biology: formerly MIPS) PlantsDB (http://pgsb.helmholtz-muenchen.de/plant/index.jsp) is a database framework for the comparative analysis and visualization of plant genome data. The resource has been updated with new data sets and types as well as specialized tools and interfaces to address user demands for intuitive access to complex plant genome data. In its latest incarnation, we have re-worked both the layout and navigation structure and implemented new keyword search options and a new BLAST sequence search functionality. Actively involved in corresponding sequencing consortia, PlantsDB has dedicated special efforts to the integration and visualization of complex triticeae genome data, especially for barley, wheat and rye. We enhanced CrowsNest, a tool to visualize syntenic relationships between genomes, with data from the wheat sub-genome progenitor Aegilops tauschii and added functionality to the PGSB RNASeqExpressionBrowser. GenomeZipper results were integrated for the genomes of barley, rye, wheat and perennial ryegrass and interactive access is granted through PlantsDB interfaces. Data exchange and cross-linking between PlantsDB and other plant genome databases is stimulated by the transPLANT project (http://transplantdb.eu/). PMID:26527721

  4. Constructing a population-based research database from routine maternal screening records: a resource for studying alloimmunization in pregnant women.

    Directory of Open Access Journals (Sweden)

    Brian K Lee

    Full Text Available BACKGROUND: Although screening for maternal red blood cell antibodies during pregnancy is a standard procedure, the prevalence and clinical consequences of non-anti-D immunization are poorly understood. The objective was to create a national database of maternal antibody screening results that can be linked with population health registers to create a research resource for investigating these issues. STUDY DESIGN AND METHODS: Each birth in the Swedish Medical Birth Register was uniquely identified and linked to the text stored in routine maternal antibody screening records in the time window from 9 months prior to 2 weeks after the delivery date. These text records were subjected to a computerized search for specific antibodies using regular expressions. To illustrate the research potential of the resulting database, selected antibody prevalence rates are presented as tables and figures, and the complete data (from more than 60 specific antibodies presented as online moving graphical displays. RESULTS: More than one million (1,191,761 births with valid screening information from 1982-2002 constitute the study population. Computerized coverage of screening increased steadily over time and varied by region as electronic records were adopted. To ensure data quality, we restricted analysis to birth records in areas and years with a sustained coverage of at least 80%, representing 920,903 births from 572,626 mothers in 17 of the 24 counties in Sweden. During the study period, non-anti-D and anti-D antibodies occurred in 76.8/10,000 and 14.1/10,000 pregnancies respectively, with marked differences between specific antibodies over time. CONCLUSION: This work demonstrates the feasibility of creating a nationally representative research database from the routine maternal antibody screening records from an extended calendar period. By linkage with population registers of maternal and child health, such data are a valuable resource for addressing important

  5. Bibliometric analysis of nutrition and dietetics research activity in Arab countries using ISI Web of Science database.

    Science.gov (United States)

    Sweileh, Waleed M; Al-Jabi, Samah W; Sawalha, Ansam F; Zyoud, Sa'ed H

    2014-01-01

    Reducing nutrition-related health problems in Arab countries requires an understanding of the performance of Arab countries in the field of nutrition and dietetics research. Assessment of research activity from a particular country or region could be achieved through bibliometric analysis. This study was carried out to investigate research activity in "nutrition and dietetics" in Arab countries. Original and review articles published from Arab countries in "nutrition and dietetics" Web of Science category up until 2012 were retrieved and analyzed using the ISI Web of Science database. The total number of documents published in "nutrition and dietetics" category from Arab countries was 2062. This constitutes 1% of worldwide research activity in the field. Annual research productivity showed a significant increase after 2005. Approximately 60% of published documents originated from three Arab countries, particularly Egypt, Kingdom of Saudi Arabia, and Tunisia. However, Kuwait has the highest research productivity per million inhabitants. Main research areas of published documents were in "Food Science/Technology" and "Chemistry" which constituted 75% of published documents compared with 25% for worldwide documents in nutrition and dietetics. A total of 329 (15.96%) nutrition - related diabetes or obesity or cancer documents were published from Arab countries compared with 21% for worldwide published documents. Interest in nutrition and dietetics research is relatively recent in Arab countries. Focus of nutrition research is mainly toward food technology and chemistry with lesser activity toward nutrition-related health research. International cooperation in nutrition research will definitely help Arab researchers in implementing nutrition research that will lead to better national policies regarding nutrition.

  6. A spatial classification and database for management, research, and policy making: The Great Lakes aquatic habitat framework

    Science.gov (United States)

    Wang, Lizhu; Riseng, Catherine M.; Mason, Lacey; Werhrly, Kevin; Rutherford, Edward; McKenna, James E.; Castiglione, Chris; Johnson, Lucinda B.; Infante, Dana M.; Sowa, Scott P.; Robertson, Mike; Schaeffer, Jeff; Khoury, Mary; Gaiot, John; Hollenhurst, Tom; Brooks, Colin N.; Coscarelli, Mark

    2015-01-01

    Managing the world's largest and most complex freshwater ecosystem, the Laurentian Great Lakes, requires a spatially hierarchical basin-wide database of ecological and socioeconomic information that is comparable across the region. To meet such a need, we developed a spatial classification framework and database — Great Lakes Aquatic Habitat Framework (GLAHF). GLAHF consists of catchments, coastal terrestrial, coastal margin, nearshore, and offshore zones that encompass the entire Great Lakes Basin. The catchments captured in the database as river pour points or coastline segments are attributed with data known to influence physicochemical and biological characteristics of the lakes from the catchments. The coastal terrestrial zone consists of 30-m grid cells attributed with data from the terrestrial region that has direct connection with the lakes. The coastal margin and nearshore zones consist of 30-m grid cells attributed with data describing the coastline conditions, coastal human disturbances, and moderately to highly variable physicochemical and biological characteristics. The offshore zone consists of 1.8-km grid cells attributed with data that are spatially less variable compared with the other aquatic zones. These spatial classification zones and their associated data are nested within lake sub-basins and political boundaries and allow the synthesis of information from grid cells to classification zones, within and among political boundaries, lake sub-basins, Great Lakes, or within the entire Great Lakes Basin. This spatially structured database could help the development of basin-wide management plans, prioritize locations for funding and specific management actions, track protection and restoration progress, and conduct research for science-based decision making.

  7. DMPD: Fifty years of interferon research: aiming at a moving target. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 16979566 Fifty years of interferon research: aiming at a moving target. Vilcek J. I...mmunity. 2006 Sep;25(3):343-8. (.png) (.svg) (.html) (.csml) Show Fifty years of interferon research: aiming... at a moving target. PubmedID 16979566 Title Fifty years of interferon research: aiming at a moving target.

  8. IAEA Coordinated Research Project on the Establishment of a Material Properties Database for Irradiated Core Structural Components for Continued Safe Operation and Lifetime Extension of Ageing Research Reactors

    International Nuclear Information System (INIS)

    Today more than 50% of operating Research Reactors (RRs) are over 45 years old. Thus, ageing management is one of the most important issues to face in order to ensure availability (including life extension), reliability and safe operation of these facilities for the future. Management of the ageing process requires, amongst others, the predictions for the behavior of structural materials of primary components subjected to irradiation such as reactor vessel and core support structures, many of which are extremely difficult or impossible to replace. In fact, age-related material degradation mechanisms resulted in high profile, unplanned and lengthy shutdowns and unique regulatory processes of relicensing the facilities in recent years. These could likely have been prevented by utilizing available data for the implementation of appropriate maintenance and surveillance programmes. This IAEA Coordinated Research Project (CRP) will provide an international forum to establish a material properties Database for irradiated core structural materials and components. It is expected that this Database will be used by research reactor operators and regulators to help predict ageing related degradation. This would be useful to minimize unpredicted outages due to ageing processes of primary components and to mitigate lengthy and costly shutdowns. The Database will be a compilation of data from RRs operators' inputs, comprehensive literature reviews and experimental data from RRs. Moreover, the CRP will specify further activities needed to be addressed in order to bridge the gaps in the new created Database, for potential follow-on activities. As per today, 13 Member States (MS) confirmed their agreement to contribute to the development of the Database, covering a wide number of materials and properties. The present publication incorporates two parts: the first part includes details on the pre-CRP Questionnaire, including the conclusions drawn from the answers received from the MS

  9. Nuclear threats in the vicinity of the Nordic countries. A database, Nordic Nuclear Safety Research

    International Nuclear Information System (INIS)

    The acute phase of an accident and the possibility of high exposure of the populations are always the most important threats in the emergency preparedness work. Radioactive contamination from an accident can however also cause long time effects for land use and enhanced doses to special population groups and economic problems for agriculture, grazing animals, reindeer industry, hunting, freshwater fishing, tourism and recreation. For planning purposes it is always valuable to be aware of potential radiation hazard and other potential threats in the vicinity of the Nordic countries. Thus, mapping such threats in a Nordic context is an important factor in emergency preparedness in the Nordic countries. The project has dealt with threats from the north west of Russia and the Baltic states. The results from the different activities in the project is generated in a web based database called the 'the base of knowledge'. (orig.)

  10. A three dimensional children head database for acoustical research and development

    DEFF Research Database (Denmark)

    Harder, Stine; Paulsen, Rasmus Reinhold; Larsen, Martin;

    2013-01-01

    Most computational-acoustic work within spatial hearing relies on head-related transfer functions from databases of measurements taken on adult humans or dummy heads. We aim to provide a set of 3D digital heads including children, from which head-related transfer functions can be computed instead...... of measured. However, current volumetric scanning techniques do not have sufficient resolution for accurately scanning the external ear, and computed tomography also involves radiation. In this paper we propose a framework for scanning, stitching and meshing complete human heads. The process starts....... The process consists of a regularized surface reconstruction step followed by an alignment step. Finally, a surface representation of the entire head is extracted using a triangulation of the zero-level iso-surface of the implicit volume. The process has been used to reconstruct the heads of children aged 10...

  11. Research And Investigation To Establish The Database Of Environment Radiation Background For Vietnam (Phase 2009 -2011)

    International Nuclear Information System (INIS)

    Setting up data base of natural radiation background serves for planning socio-economics development in a province as well as the whole country and estimating annual effective dose of population. Beside external irradiation dose caused by the natural radioisotopes in the series 238U, 232Th and 40K in soil, population has been received internal dose caused by the above radioisotopes taken in the body from several ways. In order to complete the database of national radiation background and go to estimate annual effective radiation dose of population in the whole country, this project focus to carry out the works as following: (i) Setting up database of radiation background in the whole country: 150 soil samples that collected in the districts of 46 provinces have been analyzed. The average activity concentration of 238U, 232Th and 40K are 37.86 Bq/kg, 58.88 Bq/kg and 462.78 Bq/kg, respectively. The outdoor, indoor and total annual effective doses are calculated: 0.087±0.036 mSv; 0.488±0.202 mSv and 0.576± 0.240 mSv, respectively. (ii) Setting up database of radiation background of province Ninh Thuan and Quang Nam: The detailed database of radiation background of all villages in Ninh Thuan and Quang Nam has been established. 84 soil samples in Ninh Thuan and 311 in Quang Nam were collected for analyze. The indoor and outdoor radon concentration at sampling positions has been measured. The average activities of 238U, 232Th, 40K, and 222Rn isotopes in Ninh Thuan are reported: 33.50 Bq/kg, 55.43 Bq/kg, 701.12 Bq/kg and 12.1 Bq/m3, 9.5 Bq/m3, respectively. The outdoor, indoor and total annual effective doses in Ninh Thuan are calculated: 0.095±0.029 mSv; 0.529±0.162 mSv and 0.624± 0.382 mSv, respectively. The average activities of 238U, 232Th, 40K, and 222Rn isotopes in Quang Nam are reported: 44.47 Bq/kg, 52.68 Bq/kg, 459.33 Bq/kg, 18.0 Bq/m3. The outdoor, indoor and total annual effective doses are calculated: 0.086±0.039 mSv; 0.482±0.216 mSv and 0.568± 0

  12. Research on the J2EE-based product database management system

    Institute of Scientific and Technical Information of China (English)

    LIN Lin; YAO Yu; ZHONG Shi-sheng

    2007-01-01

    The basic frame and the design idea of J2EE-based Product Data Management (PDM) system are presented. This paper adopts the technology of Object-Oriented to realize the database design and builds the information model of this PDM system. The integration key technology of PDM and CAD systems are discussed,the isomerous interface characteristics between CAD and PDM systems are analyzed, and finally, the integration mode of the PDM and CAD systems is given. Using these technologies, the integration of PDM and CAD systems is realized and the consistence of data in PDM and CAD systems is kept. Finally, the Product Data Management system is developed, which has been tested on development process of the hydraulic generator. The running process is stable and safety.

  13. Using the Homes Energy Efficiency Database as a research resource for residential insulation improvements

    International Nuclear Information System (INIS)

    In devising viable energy efficiency policies that can reduce the greenhouse gas emissions of existing dwellings (e.g. UK's Green Deal), data are required on current insulation levels and its influences. One such data source is the seldom used UK Energy Saving Trust's Homes Energy Efficiency Database (HEED), which this paper investigates using Norfolk UK local authorities as a case study. The HEED's reactive and longitudinal data collection strategies contribute to underlying biases, which is the likely reasoning for its differences with the English Housing Survey and UK 2001 Census. These differences had a cascading effect in that they manifested themselves in the indicative financial and carbon assessments undertaken. Similarly, sampling concerns also implicated correlations surrounding influences of current dwelling insulation levels. Providing one is transparent about potential biases and data concerns, the HEED can play a substantial role in guiding policy decisions and understanding dwelling stock characteristics (e.g. what makes dwellings ‘Hard to Treat'). In particular, its vast (national) geographic coverage yet high resolution enables local context to be explored: a factor that this study shows to significantly shape insulation levels. - Highlights: • The Homes Energy Efficiency Database's (HEED) integrity and role is investigated. • HEED biases exist due to reactive and longitudinal data collection strategies. • Biases contribute to differences with Census and English Housing Survey. • Its high resolution and national coverage can bring local context to the fore. • It can play a substantial role in shaping residential energy efficiency policies

  14. Comparison of 4 nutrient databases with chemical composition data from the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group.

    Science.gov (United States)

    McCullough, M L; Karanja, N M; Lin, P H; Obarzanek, E; Phillips, K M; Laws, R L; Vollmer, W M; O'Connor, E A; Champagne, C M; Windhauser, M M

    1999-08-01

    Accuracy of computerized nutrient databases is an important consideration in selecting a nutrient analysis system. We project compared the nutrient content of daily menus calculated from 4 microcomputer programs to chemical analysis of menus analyzed for the Dietary Approaches to Stop Hypertension (DASH) trial. Thirty-six menus were entered at 2 independent DASH sites using the ESHA Food Processor, Minnesota Nutrition Data System, Moore's Extended Nutrient Database, and Nutritionist IV databases. Food prepared according to these menus was chemically analyzed at the Food Analysis Laboratory Control Center at Virginia Polytechnic Institute and State University, Department of Biochemistry, Blacksburg. Estimates for 13 nutrients were compared: energy, total fat, saturated fat, monounsaturated fat, polyunsaturated fat, carbohydrate, protein, cholesterol, calcium, potassium, magnesium, iron, and sodium. The overall intraclass correlation between the 2 sites' data entry was 0.998; thus, values were averaged for analyses. Databases varied significantly in their mean deviations from chemical analyses values for saturated, monounsaturated, and polyunsaturated fatty acids, potassium, magnesium, and iron (P < .05); however, these differences were small (< 10%). Absolute deviations, which estimate the combined effect of bias and precision, were significantly different among databases for energy, saturated fatty acids, and polyunsaturated acids. Absolute differences from the laboratory values varied by < 15%, except for iron. All 4 databases were comparable in accuracy and precision and performed well. Criteria for database selection depends not only on overall database accuracy, especially for nutrients of interest, but also on the ease of use of the program, relevant features of the associated software; and cost. PMID:10450294

  15. A meta-database comparison from various European research networks dedicated to forests sites

    NARCIS (Netherlands)

    Danielewska, A.; Clarke, N.; Olejnik, J.; Hansen, K.; Vries, de W.

    2013-01-01

    Of a wide variety of international forest research and monitoring networks, several networks are dedicated to the effects of climate change on forests, while the effects of anthropogenic pollutants on forests have been a major area for both monitoring and research for decades. The large amounts of d

  16. Automatic detection of lung nodules in computed tomography images: training and validation of algorithms using public research databases

    Science.gov (United States)

    Camarlinghi, Niccolò

    2013-09-01

    Lung cancer is one of the main public health issues in developed countries. Lung cancer typically manifests itself as non-calcified pulmonary nodules that can be detected reading lung Computed Tomography (CT) images. To assist radiologists in reading images, researchers started, a decade ago, the development of Computer Aided Detection (CAD) methods capable of detecting lung nodules. In this work, a CAD composed of two CAD subprocedures is presented: , devoted to the identification of parenchymal nodules, and , devoted to the identification of the nodules attached to the pleura surface. Both CADs are an upgrade of two methods previously presented as Voxel Based Neural Approach CAD . The novelty of this paper consists in the massive training using the public research Lung International Database Consortium (LIDC) database and on the implementation of new features for classification with respect to the original VBNA method. Finally, the proposed CAD is blindly validated on the ANODE09 dataset. The result of the validation is a score of 0.393, which corresponds to the average sensitivity of the CAD computed at seven predefined false positive rates: 1/8, 1/4, 1/2, 1, 2, 4, and 8 FP/CT.

  17. Government databases and public health research: facilitating access in the public interest.

    Science.gov (United States)

    Adams, Carolyn; Allen, Judy

    2014-06-01

    Access to datasets of personal health information held by government agencies is essential to support public health research and to promote evidence-based public health policy development. Privacy legislation in Australia allows the use and disclosure of such information for public health research. However, access is not always forthcoming in a timely manner and the decision-making process undertaken by government data custodians is not always transparent. Given the public benefit in research using these health information datasets, this article suggests that it is time to recognise a right of access for approved research and that the decisions, and decision-making processes, of government data custodians should be subject to increased scrutiny. The article concludes that researchers should have an avenue of external review where access to information has been denied or unduly delayed. PMID:25087372

  18. Government databases and public health research: facilitating access in the public interest.

    Science.gov (United States)

    Adams, Carolyn; Allen, Judy

    2014-06-01

    Access to datasets of personal health information held by government agencies is essential to support public health research and to promote evidence-based public health policy development. Privacy legislation in Australia allows the use and disclosure of such information for public health research. However, access is not always forthcoming in a timely manner and the decision-making process undertaken by government data custodians is not always transparent. Given the public benefit in research using these health information datasets, this article suggests that it is time to recognise a right of access for approved research and that the decisions, and decision-making processes, of government data custodians should be subject to increased scrutiny. The article concludes that researchers should have an avenue of external review where access to information has been denied or unduly delayed.

  19. Creating a data exchange strategy for radiotherapy research: Towards federated databases and anonymised public datasets

    DEFF Research Database (Denmark)

    Skripcak, Tomas; Belka, Claus; Bosch, Walter;

    2014-01-01

    for knowledge generation within “Big Data“. Data interoperability between research institutions should be the major concern behind a wider collaboration. Information captured in electronic patient records (EPRs) and study case report forms (eCRFs), linked together with medical imaging and treatment planning......Disconnected cancer research data management and lack of information exchange about planned and ongoing research are complicating the utilisation of internationally collected medical information for improving cancer patient care. Rapidly collecting/pooling data can accelerate translational research...... in radiation therapy and oncology. The exchange of study data is one of the fundamental principles behind data aggregation and data mining. The possibilities of reproducing the original study results, performing further analyses on existing research data to generate new hypotheses or developing computational...

  20. Collaborative research between academia and industry using a large clinical trial database: a case study in Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Jones Roy

    2011-10-01

    Full Text Available Abstract Background Large clinical trials databases, developed over the course of a comprehensive clinical trial programme, represent an invaluable resource for clinical researchers. Data mining projects sponsored by industry that use these databases, however, are often not viewed favourably in the academic medical community because of concerns that commercial, rather than scientific, goals are the primary purpose of such endeavours. Thus, there are few examples of sustained collaboration between leading academic clinical researchers and industry professionals in a large-scale data mining project. We present here a successful example of this type of collaboration in the field of dementia. Methods The Donepezil Data Repository comprised 18 randomised, controlled trials conducted between 1991 and 2005. The project team at Pfizer determined that the data mining process should be guided by a diverse group of leading Alzheimer's disease clinical researchers called the "Expert Working Group." After development of a list of potential faculty members, invitations were extended and a group of seven members was assembled. The Working Group met regularly with Eisai/Pfizer clinicians and statisticians to discuss the data, identify issues that were currently of interest in the academic and clinical communities that might lend themselves to investigation using these data, and note gaps in understanding or knowledge of Alzheimer's disease that these data could address. Leadership was provided by the Pfizer Clinical Development team leader; Working Group members rotated responsibility for being lead and co-lead for each investigation and resultant publication. Results Six manuscripts, each published in a leading subspecialty journal, resulted from the group's work. Another project resulted in poster presentations at international congresses and two were cancelled due to resource constraints. Conclusions The experience represents a particular approach to

  1. Propulsion System Airframe Integration Issues and Aerodynamic Database Development for the Hyper-X Flight Research Vehicle

    Science.gov (United States)

    Engelund, Walter C.; Holland, Scott D.; Cockrell, Charles E., Jr.; Bittner, Robert D.

    1999-01-01

    NASA's Hyper-X Research Vehicle will provide a unique opportunity to obtain data on an operational airframe integrated scramjet propulsion system at true flight conditions. The airframe integrated nature of the scramjet engine with the Hyper-X vehicle results in a strong coupling effect between the propulsion system operation and the airframe s basic aerodynamic characteristics. Comments on general airframe integrated scramjet propulsion system effects on vehicle aerodynamic performance, stability, and control are provided, followed by examples specific to the Hyper-X research vehicle. An overview is provided of the current activities associated with the development of the Hyper-X aerodynamic database, including wind tunnel test activities and parallel CFD analysis efforts. A brief summary of the Hyper-X aerodynamic characteristics is provided, including the direct and indirect effects of the airframe integrated scramjet propulsion system operation on the basic airframe stability and control characteristics.

  2. Scopus database: a review.

    Science.gov (United States)

    Burnham, Judy F

    2006-03-08

    The Scopus database provides access to STM journal articles and the references included in those articles, allowing the searcher to search both forward and backward in time. The database can be used for collection development as well as for research. This review provides information on the key points of the database and compares it to Web of Science. Neither database is inclusive, but complements each other. If a library can only afford one, choice must be based in institutional needs.

  3. Scopus database: a review

    OpenAIRE

    Burnham, Judy F.

    2006-01-01

    The Scopus database provides access to STM journal articles and the references included in those articles, allowing the searcher to search both forward and backward in time. The database can be used for collection development as well as for research. This review provides information on the key points of the database and compares it to Web of Science. Neither database is inclusive, but complements each other. If a library can only afford one, choice must be based in institutional needs.

  4. Research of Cadastral Data Modelling and Database Updating Based on Spatio-temporal Process

    Directory of Open Access Journals (Sweden)

    ZHANG Feng

    2016-02-01

    Full Text Available The core of modern cadastre management is to renew the cadastre database and keep its currentness,topology consistency and integrity.This paper analyzed the changes and their linkage of various cadastral objects in the update process.Combined object-oriented modeling technique with spatio-temporal objects' evolution express,the paper proposed a cadastral data updating model based on the spatio-temporal process according to people's thought.Change rules based on the spatio-temporal topological relations of evolution cadastral spatio-temporal objects are drafted and further more cascade updating and history back trace of cadastral features,land use and buildings are realized.This model implemented in cadastral management system-ReGIS.Achieved cascade changes are triggered by the direct driving force or perceived external events.The system records spatio-temporal objects' evolution process to facilitate the reconstruction of history,change tracking,analysis and forecasting future changes.

  5. Improving quality of breast cancer surgery through development of a national breast cancer surgical outcomes (BRCASO) research database

    International Nuclear Information System (INIS)

    Common measures of surgical quality are 30-day morbidity and mortality, which poorly describe breast cancer surgical quality with extremely low morbidity and mortality rates. Several national quality programs have collected additional surgical quality measures; however, program participation is voluntary and results may not be generalizable to all surgeons. We developed the Breast Cancer Surgical Outcomes (BRCASO) database to capture meaningful breast cancer surgical quality measures among a non-voluntary sample, and study variation in these measures across providers, facilities, and health plans. This paper describes our study protocol, data collection methods, and summarizes the strengths and limitations of these data. We included 4524 women ≥18 years diagnosed with breast cancer between 2003-2008. All women with initial breast cancer surgery performed by a surgeon employed at the University of Vermont or three Cancer Research Network (CRN) health plans were eligible for inclusion. From the CRN institutions, we collected electronic administrative data including tumor registry information, Current Procedure Terminology codes for breast cancer surgeries, surgeons, surgical facilities, and patient demographics. We supplemented electronic data with medical record abstraction to collect additional pathology and surgery detail. All data were manually abstracted at the University of Vermont. The CRN institutions pre-filled 30% (22 out of 72) of elements using electronic data. The remaining elements, including detailed pathology margin status and breast and lymph node surgeries, required chart abstraction. The mean age was 61 years (range 20-98 years); 70% of women were diagnosed with invasive ductal carcinoma, 20% with ductal carcinoma in situ, and 10% with invasive lobular carcinoma. The BRCASO database is one of the largest, multi-site research resources of meaningful breast cancer surgical quality data in the United States. Assembling data from electronic

  6. Veterans Administration Databases

    Science.gov (United States)

    The Veterans Administration Information Resource Center provides database and informatics experts, customer service, expert advice, information products, and web technology to VA researchers and others.

  7. In search of yoga: Research trends in a western medical database

    Directory of Open Access Journals (Sweden)

    Marcy C McCall

    2014-01-01

    Conclusions: The prevalence of yoga research in western healthcare is increasing. The marked increase in volume indicates the need for more systematic analysis of the literature in terms of quality and results.

  8. Huntington's Disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database

    Directory of Open Access Journals (Sweden)

    Kalathur Ravi Kiran

    2012-06-01

    Full Text Available Abstract Background Huntington’s disease (HD is a fatal progressive neurodegenerative disorder caused by the expansion of the polyglutamine repeat region in the huntingtin gene. Although the disease is triggered by the mutation of a single gene, intensive research has linked numerous other genes to its pathogenesis. To obtain a systematic overview of these genes, which may serve as therapeutic targets, CHDI Foundation has recently established the HD Research Crossroads database. With currently over 800 cataloged genes, this web-based resource constitutes the most extensive curation of genes relevant to HD. It provides us with an unprecedented opportunity to survey molecular mechanisms involved in HD in a holistic manner. Methods To gain a synoptic view of therapeutic targets for HD, we have carried out a variety of bioinformatical and statistical analyses to scrutinize the functional association of genes curated in the HD Research Crossroads database. In particular, enrichment analyses were performed with respect to Gene Ontology categories, KEGG signaling pathways, and Pfam protein families. For selected processes, we also analyzed differential expression, using published microarray data. Additionally, we generated a candidate set of novel genetic modifiers of HD by combining information from the HD Research Crossroads database with previous genome-wide linkage studies. Results Our analyses led to a comprehensive identification of molecular mechanisms associated with HD. Remarkably, we not only recovered processes and pathways, which have frequently been linked to HD (such as cytotoxicity, apoptosis, and calcium signaling, but also found strong indications for other potentially disease-relevant mechanisms that have been less intensively studied in the context of HD (such as the cell cycle and RNA splicing, as well as Wnt and ErbB signaling. For follow-up studies, we provide a regularly updated compendium of molecular mechanism, that are

  9. Amino acid sequences used for clusterintg (Multi FASTA format) - Gclust Server | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available Gclust Server Amino acid sequences used for clusterintg (Multi FASTA format) Data detail Data name Amino acid sequence...s used for clusterintg (Multi FASTA format) Description of data contents Amino acid sequences of p...a entries - FASTA format header: ID and the annotation information of the sequence... Site Policy | Contact Us Amino acid sequences used for clusterintg (Multi FASTA format) - Gclust Server | LSDB Archive ...

  10. Further Research is Required to Determine Which Database Products Best Support Research in Public Administration. A review of: Tucker, James, Corey. “Database Support for Research in Public Administration.” Behavioral & Social Sciences Librarian 24.1 (2005): 47-60.

    OpenAIRE

    David Hook

    2006-01-01

    Objective – To examine the extent to which six commercial database products support student and faculty research in the area of public administration. Design – Bibliometric study. Setting – Academic library in the United States. Subjects – Six commercial business‐related database products were examined: Proquest’s ABI/INFORM Global edition (ABI), EBSCO’s Business Source Premier (BSP), Gale’s General BusinessFile ASAP (GBF), EBSCO’s Academic Search Premier (ASP), EBSCO’s Expanded ...

  11. Cloud Databases: A Paradigm Shift in Databases

    Directory of Open Access Journals (Sweden)

    Indu Arora

    2012-07-01

    Full Text Available Relational databases ruled the Information Technology (IT industry for almost 40 years. But last few years have seen sea changes in the way IT is being used and viewed. Stand alone applications have been replaced with web-based applications, dedicated servers with multiple distributed servers and dedicated storage with network storage. Cloud computing has become a reality due to its lesser cost, scalability and pay-as-you-go model. It is one of the biggest changes in IT after the rise of World Wide Web. Cloud databases such as Big Table, Sherpa and SimpleDB are becoming popular. They address the limitations of existing relational databases related to scalability, ease of use and dynamic provisioning. Cloud databases are mainly used for data-intensive applications such as data warehousing, data mining and business intelligence. These applications are read-intensive, scalable and elastic in nature. Transactional data management applications such as banking, airline reservation, online e-commerce and supply chain management applications are write-intensive. Databases supporting such applications require ACID (Atomicity, Consistency, Isolation and Durability properties, but these databases are difficult to deploy in the cloud. The goal of this paper is to review the state of the art in the cloud databases and various architectures. It further assesses the challenges to develop cloud databases that meet the user requirements and discusses popularly used Cloud databases.

  12. The epidemiology and burden of Alzheimer’s disease in Taiwan utilizing data from the National Health Insurance Research Database

    Science.gov (United States)

    Hung, Yen-Ni; Kadziola, Zbigniew; Brnabic, Alan JM; Yeh, Ju-Fen; Fuh, Jong-Ling; Hwang, Jen-Ping; Montgomery, William

    2016-01-01

    Purpose The objectives of this study were to estimate the incidence, cumulative incidence, and economic burden of Alzheimer’s disease (AD) in Taiwan, using data from the National Health Insurance Research Database (NHIRD). Materials and methods This was a retrospective, longitudinal, observational study using data from the Longitudinal Health Insurance Database of the NHIRD. Patients were included in this study if they were 50 years of age or older and their records included a primary or secondary diagnosis of AD. New patients who met inclusion criteria were followed up longitudinally from 2005 to 2010. Costs were calculated for the first year following the diagnosis of AD. Results Overall, a higher percentage of women than men were diagnosed with AD (54% vs 46%, respectively). The first AD diagnosis occurred most frequently in the age of 75–84 years. The person-year incidence rate increased from 5.63/1,000 persons (95% CI, 5.32–5.94) in 2005 to 8.17/1,000 persons (95% CI, 7.78–8.57) in 2010. The cumulative incidence rate was 33.54/1,000 persons (95% CI, 32.76–34.33) in 2005–2010. The total mean inflated annual costs per patient in new Taiwan dollars (NT$) in the first year of diagnosis ranged from NT$205,413 (2009) to NT$227,110 (2005), with hospitalization representing the largest component. Conclusion AD represents a substantial burden in Taiwan, and based on the observed increase in incidence rate over time, it is likely that this burden will continue to increase. The findings reported here are consistent with previous research. The NHIRD contains extensive real-world information that can be used to conduct research, allowing us to expand our understanding of the incidence, prevalence, and burden of disease in Taiwan. PMID:27536149

  13. Biological Macromolecule Crystallization Database

    Science.gov (United States)

    SRD 21 Biological Macromolecule Crystallization Database (Web, free access)   The Biological Macromolecule Crystallization Database and NASA Archive for Protein Crystal Growth Data (BMCD) contains the conditions reported for the crystallization of proteins and nucleic acids used in X-ray structure determinations and archives the results of microgravity macromolecule crystallization studies.

  14. Reliability Of A Surgeon-Reported Morbidity And Mortality Database: A Comparison Of Short-Term Morbidity Between The Scoliosis Research Society And National Surgical Quality Improvement Program Databases

    Science.gov (United States)

    Martin, Christopher T.; Pugely, Andrew J.; Gao, Yubo; Skovrlj, Branko; Lee, Nathan J.; Cho, Samuel K.; Mendoza-Lattes, Sergio

    2016-01-01

    Background There exists a lack of comparison between large national healthcare databases reporting surgical morbidity and mortality. Prior authors have expressed concern that the Scoliosis Research Society (SRS) membership may have underreported complications in spinal surgery. Thus, the purpose of the present study was to compare the incidence of morbidity between the SRS and National Surgical Quality Improvement Program (NSQIP) databases. Methods We reviewed patients enrolled between 2012 and 2013, with a total of 96,875 patients identified in the SRS dataset and 15,909 in the combined adult and pediatric NSQIP dataset. Patients were matched based on diagnostic category,and a univariate analysis was used to compare reported complication rates in the categories of perioperative infection, neurologic injury, and mortality. The SRS database only requires detailed demographic data reporting on patients that have had a complication event. We compared the demographics and comorbidities of this subgroup, and used this as a surrogate to assess the potential magnitude of confounders. Results Small differences existed between the SRS and NSQIP databases in terms of mortality (0.1% v. 0.2%), infection (1.2% v. 2%), and neurologic injury (0.8% v. 0.1%) (p<0.001 for each comparison). Infection rates were consistently lower across multiple diagnostic sub-categories in the SRS database, whereas neurologic injury rates were consistently lower in the NSQIP database. These differences reached statistical significance across several diagnostic subcategories, but the clinical magnitude of the differences was small. Amongst the patients with a complication, modest differences in comorbidities existed between the two cohorts. Conclusion Overall, the incidence of short-term morbidity and mortality was similar between the two databases. There were modest differences in comorbidities, which may explain the small differences observed in morbidity. Concerns regarding possible under

  15. Linking CALL and SLA: Using the IRIS Database to Locate Research Instruments

    Science.gov (United States)

    Handley, Zöe; Marsden, Emma

    2014-01-01

    To establish an evidence base for future computer-assisted language learning (CALL) design, CALL research needs to move away from CALL versus non-CALL comparisons, and focus on investigating the differential impact of individual coding elements, that is, specific features of a technology which might have an impact on learning (Pederson, 1987).…

  16. The Cerebral Blood Flow Biomedical Informatics Research Network (CBFBIRN) database and analysis pipeline for arterial spin labeling MRI data.

    Science.gov (United States)

    Shin, David D; Ozyurt, I Burak; Liu, Thomas T

    2013-01-01

    Arterial spin labeling (ASL) is a magnetic resonance imaging technique that provides a non-invasive and quantitative measure of cerebral blood flow (CBF). After more than a decade of active research, ASL is now emerging as a robust and reliable CBF measurement technique with increased availability and ease of use. There is a growing number of research and clinical sites using ASL for neuroscience research and clinical care. In this paper, we present an online CBF Database and Analysis Pipeline, collectively called the Cerebral Blood Flow Biomedical Informatics Research Network (CBFBIRN) that allows researchers to upload and share ASL and clinical data. In addition to serving the role as a central data repository, the CBFBIRN provides a streamlined data processing infrastructure for CBF quantification and group analysis, which has the potential to accelerate the discovery of new scientific and clinical knowledge. All capabilities and features built into the CBFBIRN are accessed online using a web browser through a secure login. In this work, we begin with a general description of the CBFBIRN system data model and its architecture, then devote the remainder of the paper to the CBFBIRN capabilities. The latter part of our work is divided into two processing modules: (1) Data Upload and CBF Quantification Module; (2) Group Analysis Module that supports three types of analysis commonly used in neuroscience research. To date, the CBFBIRN hosts CBF maps and associated clinical data from more than 1,300 individual subjects. The data have been contributed by more than 20 different research studies, investigating the effect of various conditions on CBF including Alzheimer's, schizophrenia, bipolar disorder, depression, traumatic brain injury, HIV, caffeine usage, and methamphetamine abuse. Several example results, generated by the CBFBIRN processing modules, are presented. We conclude with the lessons learned during implementation and deployment of the CBFBIRN and our

  17. SPIN Query Tools for De-identified Research on a Humongous Database

    OpenAIRE

    McDonald, Clement J.; Dexter, Paul; Schadow, Gunther; Chueh, Henry C.; Abernathy, Greg; Hook, John; Blevins, Lonnie; Overhage, J Marc; Jules J Berman

    2005-01-01

    The Shared Pathology Informatics Network (SPIN), a research initiative of the National Cancer Institute, will allow for the retrieval of more than 4 million pathology reports and specimens. In this paper, we describe the special query tool as developed for the Indianapolis/Regenstrief SPIN node, integrated into the ever-expanding Indiana Network for Patient care (INPC). This query tool allows for the retrieval of de-identified data sets using complex logic, auto-coded final ...

  18. In search of yoga: Research trends in a western medical database

    OpenAIRE

    Marcy C McCall

    2014-01-01

    Context: The promotion of yoga practice as a preventative and treatment therapy for health outcomes in the western hemisphere is increasing rapidly. As the commercial success of yoga burgeons in popular culture, it is important to investigate the trends of yoga as a therapeutic intervention in academic literature. The free-access search engine, PubMed is a preeminent resource to identify health-related research articles published for academics, health practitioners and others. Aims: To rep...

  19. Research on an expert system for database operation of simulation-emulation math models. Volume 1, Phase 1: Results

    Science.gov (United States)

    Kawamura, K.; Beale, G. O.; Schaffer, J. D.; Hsieh, B. J.; Padalkar, S.; Rodriguez-Moscoso, J. J.

    1985-01-01

    The results of the first phase of Research on an Expert System for Database Operation of Simulation/Emulation Math Models, is described. Techniques from artificial intelligence (AI) were to bear on task domains of interest to NASA Marshall Space Flight Center. One such domain is simulation of spacecraft attitude control systems. Two related software systems were developed to and delivered to NASA. One was a generic simulation model for spacecraft attitude control, written in FORTRAN. The second was an expert system which understands the usage of a class of spacecraft attitude control simulation software and can assist the user in running the software. This NASA Expert Simulation System (NESS), written in LISP, contains general knowledge about digital simulation, specific knowledge about the simulation software, and self knowledge.

  20. DMPD: Regulation of arachidonic acid release and cytosolic phospholipase A2activation. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 10080535 Regulation of arachidonic acid release and cytosolic phospholipase A2activ...on of arachidonic acid release and cytosolic phospholipase A2activation. PubmedID 10080535 Title Regulation of arachidonic acid relea...ation. Gijon MA, Leslie CC. J Leukoc Biol. 1999 Mar;65(3):330-6. (.png) (.svg) (.html) (.csml) Show Regulati...se and cytosolic phospholipase A2activation. Authors Gij

  1. The Cerebral Blood Flow Biomedical Informatics Research Network (CBFBIRN Database and Analysis Pipeline for Arterial Spin Labeling MRI Data

    Directory of Open Access Journals (Sweden)

    David D. Shin

    2013-10-01

    Full Text Available Arterial spin labeling (ASL is a MRI technique that provides a noninvasive and quantitative measure of cerebral blood flow (CBF. After more than a decade of active research, ASL is now emerging as a robust and reliable CBF measurement technique with increased availability and ease of use. There is a growing number of research and clinical sites using ASL for neuroscience research and clinical care. In this paper, we present an online CBF Database and Analysis Pipeline, collectively called the CBFBIRN that allows researchers to upload and share ASL and clinical data. In addition to serving the role as a central data repository, the CBFBIRN provides a streamlined data processing infrastructure for CBF quantification and group analysis, which has the potential to accelerate the discovery of new scientific and clinical knowledge. All capabilities and features built into the CBFBIRN are accessed online using a web browser through a secure login. In this work, we begin with a general description of the CBFBIRN system data model and its architecture, then devote the remainder of the paper to the CBFBIRN capabilities. The latter part of our work is divided into two processing modules: 1 Data Upload and CBF Quantification Module; 2 Group Analysis Module that supports three types of analysis commonly used in neuroscience research. To date, the CBFBIRN hosts CBF maps and associated clinical data from more than 1300 individual subjects. The data have been contributed by more than 20 different research studies, investigating the effect of various conditions on CBF including Alzheimer’s, schizophrenia, bipolar disorder, depression, traumatic brain injury, HIV, caffeine usage and Methamphetamine abuse. Several example results, generated by the CBFBIRN processing modules, are presented. We conclude with the lessons learned during implementation and deployment of the CBFBIRN and our experience in promoting data sharing.

  2. Heart research advances using database search engines, Human Protein Atlas and the Sydney Heart Bank.

    Science.gov (United States)

    Li, Amy; Estigoy, Colleen; Raftery, Mark; Cameron, Darryl; Odeberg, Jacob; Pontén, Fredrik; Lal, Sean; Dos Remedios, Cristobal G

    2013-10-01

    This Methodological Review is intended as a guide for research students who may have just discovered a human "novel" cardiac protein, but it may also help hard-pressed reviewers of journal submissions on a "novel" protein reported in an animal model of human heart failure. Whether you are an expert or not, you may know little or nothing about this particular protein of interest. In this review we provide a strategic guide on how to proceed. We ask: How do you discover what has been published (even in an abstract or research report) about this protein? Everyone knows how to undertake literature searches using PubMed and Medline but these are usually encyclopaedic, often producing long lists of papers, most of which are either irrelevant or only vaguely relevant to your query. Relatively few will be aware of more advanced search engines such as Google Scholar and even fewer will know about Quertle. Next, we provide a strategy for discovering if your "novel" protein is expressed in the normal, healthy human heart, and if it is, we show you how to investigate its subcellular location. This can usually be achieved by visiting the website "Human Protein Atlas" without doing a single experiment. Finally, we provide a pathway to discovering if your protein of interest changes its expression level with heart failure/disease or with ageing.

  3. Children's Culture Database (CCD)

    DEFF Research Database (Denmark)

    Wanting, Birgit

    a Dialogue inspired database with documentation, network (individual and institutional profiles) and current news , paper presented at the research seminar: Electronic access to fiction, Copenhagen, November 11-13, 1996......a Dialogue inspired database with documentation, network (individual and institutional profiles) and current news , paper presented at the research seminar: Electronic access to fiction, Copenhagen, November 11-13, 1996...

  4. DMPD: Nucleic acid-sensing Toll-like receptors: beyond ligand search. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 18321608 Nucleic acid-sensing Toll-like receptors: beyond ligand search. Miyake K. ...Adv Drug Deliv Rev. 2008 Apr 29;60(7):782-5. Epub 2008 Feb 15. (.png) (.svg) (.html) (.csml) Show Nucleic ac...id-sensing Toll-like receptors: beyond ligand search. PubmedID 18321608 Title Nucleic acid-sensing Toll-like

  5. Rat Genome Database (RGD)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Rat Genome Database (RGD) is a collaborative effort between leading research institutions involved in rat genetic and genomic research to collect, consolidate,...

  6. Database Publication Practices

    DEFF Research Database (Denmark)

    Bernstein, P.A.; DeWitt, D.; Heuer, A.;

    2005-01-01

    There has been a growing interest in improving the publication processes for database research papers. This panel reports on recent changes in those processes and presents an initial cut at historical data for the VLDB Journal and ACM Transactions on Database Systems.......There has been a growing interest in improving the publication processes for database research papers. This panel reports on recent changes in those processes and presents an initial cut at historical data for the VLDB Journal and ACM Transactions on Database Systems....

  7. An open-database of Grape Harvest dates for climate research: data description and quality assessment

    Directory of Open Access Journals (Sweden)

    V. Daux

    2011-11-01

    not homogenous. Extremely late years all occur during a two-century long time-window from the early 17th to the early 19th century, while extremely early years are frequent during the 16th and since the mid-19th century.

    The dataset is made accessible for climate research through the Internet. It should allow a variety of climate studies, including reconstructions of atmospheric circulation over Western Europe.

  8. Summary Report on the 2. Research Coordination Meeting on Development of a Reference Database for Particle-Induced Gamma Ray Emission (PIGE) Spectroscopy

    International Nuclear Information System (INIS)

    The Second Research Coordination Meeting (RCM) of the IAEA Coordinated Research Project (CRP) on 'Development of a Reference Database for Particle-Induced Gamma-ray Emission (PIGE) Spectroscopy' was held at the IAEA, Vienna, from 8 - 12 October 2012. A summary of the participants' presentations is given as well as background information and recommendations concerning the methodology for the remaining part of the CRP. The feasibility of performing evaluations and developing computer codes to implement the PIGE database was discussed. A list of pending measurements was produced and the monitoring, compilation and assessment of these data was assigned to participants. (author)

  9. Summary report of the first research coordination meeting on development of a reference database for particle-induced gamma ray emission (PIGE) spectroscopy

    International Nuclear Information System (INIS)

    The First Research Coordination Meeting (RCM) of the IAEA Coordinated Research Project (CRP) on 'Development of a Reference Database for Particle-Induced Gamma-ray Emission (PIGE) Spectroscopy' was held at the IAEA, Vienna, from 16-20 May 2011. A summary of the participants' presentations is given as well as background information, objectives and recommendations concerning approach and methodology. The extension of the IBANDL database format to include PIGE data was discussed. The different tasks to achieve the CRP objectives were assigned to participants. A list of priority measurements was produced and the individual sets of measurements assigned to participants. (author)

  10. Database Description - RMG | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available ational Institute of Agrobiological Sciences E-mail : Database classification Nucleotide Sequence Databases ...s. Background and funding This database was constructed using the research results of the National Institute of Agrobiological... information Database maintenance site National Institute of Agrobiological Sciences URL of the original web... Sciences and the University of Tokyo. Pioneer Research Project (2001-2003) of the National Institute of Agrobiolog...ical Sciences Grant-in-Aid for Scientific Research (2001-2003) of the University of

  11. Research of the Occupational Psychological Impact Factors Based on the Frequent Item Mining of the Transactional Database

    OpenAIRE

    Cheng Dongmei; Zuo Xuejun; Liu Zhaohua

    2015-01-01

    Based on the massive reading of data mining and association rules mining documents, this paper will start from compressing transactional database and propose the frequent complementary item storage structure of the transactional database. According to the previous analysis, this paper will also study the association rules mining algorithm based on the frequent complementary item storage structure of the transactional database. At last, this paper will apply this mining algorithm in the test r...

  12. Improving database design teaching in secondary education: action research implementation for documentation of didactic requirements and strategies

    OpenAIRE

    Fessakis, George; Dimitracopoulou, Angelique; Komis, Vassilis

    2005-01-01

    This is the authors version of the journal article, published in Computers in Human Behavior © Elsevier Ltd. 2005 available at http://dx.doi.org/10.1016/j.chb.2004.06.006 Database design and use has educational interest for utilitarian and learning reasons. Database technology has significant economic impact and the demand for database design can not be covered by the existent educated experts. Furthermore the database management systems available at schools could be used for the design an...

  13. Conditioning Probabilistic Databases

    CERN Document Server

    Koch, Christoph

    2008-01-01

    Past research on probabilistic databases has studied the problem of answering queries on a static database. Application scenarios of probabilistic databases however often involve the conditioning of a database using additional information in the form of new evidence. The conditioning problem is thus to transform a probabilistic database of priors into a posterior probabilistic database which is materialized for subsequent query processing or further refinement. It turns out that the conditioning problem is closely related to the problem of computing exact tuple confidence values. It is known that exact confidence computation is an NP-hard problem. This has lead researchers to consider approximation techniques for confidence computation. However, neither conditioning nor exact confidence computation can be solved using such techniques. In this paper we present efficient techniques for both problems. We study several problem decomposition methods and heuristics that are based on the most successful search techn...

  14. Relational databases

    CERN Document Server

    Bell, D A

    1986-01-01

    Relational Databases explores the major advances in relational databases and provides a balanced analysis of the state of the art in relational databases. Topics covered include capture and analysis of data placement requirements; distributed relational database systems; data dependency manipulation in database schemata; and relational database support for computer graphics and computer aided design. This book is divided into three sections and begins with an overview of the theory and practice of distributed systems, using the example of INGRES from Relational Technology as illustration. The

  15. An organic database system

    OpenAIRE

    Kersten, Martin; Siebes, Arno

    1999-01-01

    The pervasive penetration of database technology may suggest that we have reached the end of the database research era. The contrary is true. Emerging technology, in hardware, software, and connectivity, brings a wealth of opportunities to push technology to a new level of maturity. Furthermore, ground breaking results are obtained in Quantum- and DNA-computing using nature as inspiration for its computational models. This paper provides a vision on a new brand of database architectures, i.e....

  16. Nuclear Science References Database

    OpenAIRE

    PRITYCHENKO B.; Běták, E.; B. Singh; Totans, J.

    2013-01-01

    The Nuclear Science References (NSR) database together with its associated Web interface, is the world's only comprehensive source of easily accessible low- and intermediate-energy nuclear physics bibliographic information for more than 210,000 articles since the beginning of nuclear science. The weekly-updated NSR database provides essential support for nuclear data evaluation, compilation and research activities. The principles of the database and Web application development and maintenance...

  17. KALIMER database development (database configuration and design methodology)

    International Nuclear Information System (INIS)

    KALIMER Database is an advanced database to utilize the integration management for Liquid Metal Reactor Design Technology Development using Web Applicatins. KALIMER Design database consists of Results Database, Inter-Office Communication (IOC), and 3D CAD database, Team Cooperation system, and Reserved Documents, Results Database is a research results database during phase II for Liquid Metal Reactor Design Technology Develpment of mid-term and long-term nuclear R and D. IOC is a linkage control system inter sub project to share and integrate the research results for KALIMER. 3D CAD Database is s schematic design overview for KALIMER. Team Cooperation System is to inform team member of research cooperation and meetings. Finally, KALIMER Reserved Documents is developed to manage collected data and several documents since project accomplishment. This report describes the features of Hardware and Software and the Database Design Methodology for KALIMER

  18. Biofuel Database

    Science.gov (United States)

    Biofuel Database (Web, free access)   This database brings together structural, biological, and thermodynamic data for enzymes that are either in current use or are being considered for use in the production of biofuels.

  19. Community Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This excel spreadsheet is the result of merging at the port level of several of the in-house fisheries databases in combination with other demographic databases...

  20. Preliminary results of the Social Impact Research Group of MEDEX: the request database (2000–2002 of two Meteorological Services

    Directory of Open Access Journals (Sweden)

    J. Amaro

    2010-12-01

    Full Text Available One of the aims of the MEDEX project is to improve the knowledge of high-impact weather events in the Mediterranean. According to the guidelines of this project, a pilot study was carried out in two regions of Spain (the Balearic Islands and Catalonia by the Social Impact Research group of MEDEX. The main goal is to suggest some general and suitable criteria about how to analyse requests received in Meteorological Services arising out of the damage caused by weather events. Thus, all the requests received between 2000 and 2002 at the Servei Meteorològic de Catalunya as well as at the Division of AEMET in the Balearic Islands were analysed.

    Firstly, the proposed criteria in order to build the database are defined and discussed. Secondly, the temporal distribution of the requests for damage claims is analysed. On average, almost half of them were received during the first month after the event happened. During the first six months, the percentage increases by 90%. Thirdly, various factors are taken into account to determine the impact of specific events on society. It is remarkable that the greatest number of requests is for those episodes with simultaneous heavy rain and strong wind, and finally, those that are linked to high population density.

  1. ZIKV – CDB: A Collaborative Database to Guide Research Linking SncRNAs and ZIKA Virus Disease Symptoms

    Science.gov (United States)

    Morais, Daniel Kumazawa; Cuadros-Orellana, Sara; Pais, Fabiano Sviatopolk-Mirsky; Medeiros, Julliane Dutra; Geraldo, Juliana Assis; Gilbert, Jack; Volpini, Angela Cristina; Fernandes, Gabriel Rocha

    2016-01-01

    Background In early 2015, a ZIKA Virus (ZIKV) infection outbreak was recognized in northeast Brazil, where concerns over its possible links with infant microcephaly have been discussed. Providing a causal link between ZIKV infection and birth defects is still a challenge. MicroRNAs (miRNAs) are small noncoding RNAs (sncRNAs) that regulate post-transcriptional gene expression by translational repression, and play important roles in viral pathogenesis and brain development. The potential for flavivirus-mediated miRNA signalling dysfunction in brain-tissue development provides a compelling hypothesis to test the perceived link between ZIKV and microcephaly. Methodology/Principal Findings Here, we applied in silico analyses to provide novel insights to understand how Congenital ZIKA Syndrome symptoms may be related to an imbalance in miRNAs function. Moreover, following World Health Organization (WHO) recommendations, we have assembled a database to help target investigations of the possible relationship between ZIKV symptoms and miRNA-mediated human gene expression. Conclusions/Significance We have computationally predicted both miRNAs encoded by ZIKV able to target genes in the human genome and cellular (human) miRNAs capable of interacting with ZIKV genomes. Our results represent a step forward in the ZIKV studies, providing new insights to support research in this field and identify potential targets for therapy. PMID:27332714

  2. ZIKV - CDB: A Collaborative Database to Guide Research Linking SncRNAs and ZIKA Virus Disease Symptoms.

    Directory of Open Access Journals (Sweden)

    Victor Satler Pylro

    2016-06-01

    Full Text Available In early 2015, a ZIKA Virus (ZIKV infection outbreak was recognized in northeast Brazil, where concerns over its possible links with infant microcephaly have been discussed. Providing a causal link between ZIKV infection and birth defects is still a challenge. MicroRNAs (miRNAs are small noncoding RNAs (sncRNAs that regulate post-transcriptional gene expression by translational repression, and play important roles in viral pathogenesis and brain development. The potential for flavivirus-mediated miRNA signalling dysfunction in brain-tissue development provides a compelling hypothesis to test the perceived link between ZIKV and microcephaly.Here, we applied in silico analyses to provide novel insights to understand how Congenital ZIKA Syndrome symptoms may be related to an imbalance in miRNAs function. Moreover, following World Health Organization (WHO recommendations, we have assembled a database to help target investigations of the possible relationship between ZIKV symptoms and miRNA-mediated human gene expression.We have computationally predicted both miRNAs encoded by ZIKV able to target genes in the human genome and cellular (human miRNAs capable of interacting with ZIKV genomes. Our results represent a step forward in the ZIKV studies, providing new insights to support research in this field and identify potential targets for therapy.

  3. Changes in Trans Fatty Acid Profiles for Selected Snack Foods in the USDA National Nutrient Database for Standard Reference

    Science.gov (United States)

    Historically, many snack foods had been formulated with partially hydrogenated vegetable oils, the primary contributor of trans fatty acids (TFA) in the US diet. Health concerns about TFA and saturated fat intake and increased risk for chronic health disorders have prompted some manufacturers to ref...

  4. How mono-valent cations bend peptide turns and a first-principles database of amino acids and dipeptides

    Science.gov (United States)

    Baldauf, Carsten; Ropo, Matti; Blum, Volker; Scheffler, Matthias

    2014-10-01

    In this contribution we detail our efforts to investigate the structural effects of cations binding to peptides and amino acids. We perform first-principles studies employing long-range dispersion-corrected approximate density-functional theory and compare to gas-phase experiments.

  5. Database Administrator

    Science.gov (United States)

    Moore, Pam

    2010-01-01

    The Internet and electronic commerce (e-commerce) generate lots of data. Data must be stored, organized, and managed. Database administrators, or DBAs, work with database software to find ways to do this. They identify user needs, set up computer databases, and test systems. They ensure that systems perform as they should and add people to the…

  6. Study text and sets of questions for the training and examination of selected personnel of nuclear research facilities. Issue 6. Database of examination questions

    International Nuclear Information System (INIS)

    The publication is divided into 2 basic parts: the first part deals with the structure of the database and with how the exam tests are generated, the second part contains examination questions for all nuclear research facilities, both for the oral and written parts. An example of a generated test for the written part of the exam is given. (author)

  7. Reanalysis of two studies with contrasting results on the association between statin use and fracture risk : the General Practice Research Database

    NARCIS (Netherlands)

    de Vries, Frank; de Vries, Corinne; Cooper, Cyrus; Leufkens, Bert; van Staa, Tjeerd-Pieter

    2006-01-01

    BACKGROUND: Two recent case-control studies by Meier et al. and van Staa et al. used the UK General Practice Research Database (GPRD) to examine the association between the use of statins and the risk of fractures, with different results. The objective of the present study was to examine methodologi

  8. Reducing the probability of false positive research findings by pre-publication validation – Experience with a large multiple sclerosis database

    Directory of Open Access Journals (Sweden)

    Heinz Moritz

    2008-04-01

    Full Text Available Abstract Background Published false positive research findings are a major problem in the process of scientific discovery. There is a high rate of lack of replication of results in clinical research in general, multiple sclerosis research being no exception. Our aim was to develop and implement a policy that reduces the probability of publishing false positive research findings. We have assessed the utility to work with a pre-publication validation policy after several years of research in the context of a large multiple sclerosis database. Methods The large database of the Sylvia Lawry Centre for Multiple Sclerosis Research was split in two parts: one for hypothesis generation and a validation part for confirmation of selected results. We present case studies from 5 finalized projects that have used the validation policy and results from a simulation study. Results In one project, the "relapse and disability" project as described in section II (example 3, findings could not be confirmed in the validation part of the database. The simulation study showed that the percentage of false positive findings can exceed 20% depending on variable selection. Conclusion We conclude that the validation policy has prevented the publication of at least one research finding that could not be validated in an independent data set (and probably would have been a "true" false-positive finding over the past three years, and has led to improved data analysis, statistical programming, and selection of hypotheses. The advantages outweigh the lost statistical power inherent in the process.

  9. An organic database system

    NARCIS (Netherlands)

    Kersten, M.L.; Siebes, A.P.J.M.

    1999-01-01

    The pervasive penetration of database technology may suggest that we have reached the end of the database research era. The contrary is true. Emerging technology, in hardware, software, and connectivity, brings a wealth of opportunities to push technology to a new level of maturity. Furthermore, gro

  10. Hydrogen-bond landscapes, geometry and energetics of squaric acid and its mono- and dianions: a Cambridge Structural Database, IsoStar and computational study.

    Science.gov (United States)

    Allen, Frank H; Cruz-Cabeza, Aurora J; Wood, Peter A; Bardwell, David A

    2013-10-01

    As part of a programme of work to extend central-group coverage in the Cambridge Crystallographic Data Centre's (CCDC) IsoStar knowledge base of intermolecular interactions, we have studied the hydrogen-bonding abilities of squaric acid (H2SQ) and its mono- and dianions (HSQ(-) and SQ(2-)) using the Cambridge Structural Database (CSD) along with dispersion-corrected density functional theory (DFT-D) calculations for a range of hydrogen-bonded dimers. The -OH and -C=O groups of H2SQ, HSQ(-) and SQ(2-) are potent donors and acceptors, as indicated by their hydrogen-bond geometries in available crystal structures in the CSD, and by the attractive energies calculated for their dimers with acetone and methanol, which were used as model acceptors and donors. The two anions have sufficient examples in the CSD for their addition as new central groups in IsoStar. It is also shown that charge- and resonance-assisted hydrogen bonds involving H2SQ and HSQ(-) are similar in strength to those made by carboxylate COO(-) acceptors, while hydrogen bonds made by the dianion SQ(2-) are somewhat stronger. The study reinforces the value of squaric acid and its anions as cocrystal formers and their actual and potential importance as isosteric replacements for carboxylic acid and carboxylate functions.

  11. Hydrogen-bond landscapes, geometry and energetics of squaric acid and its mono- and dianions: a Cambridge Structural Database, IsoStar and computational study.

    Science.gov (United States)

    Allen, Frank H; Cruz-Cabeza, Aurora J; Wood, Peter A; Bardwell, David A

    2013-10-01

    As part of a programme of work to extend central-group coverage in the Cambridge Crystallographic Data Centre's (CCDC) IsoStar knowledge base of intermolecular interactions, we have studied the hydrogen-bonding abilities of squaric acid (H2SQ) and its mono- and dianions (HSQ(-) and SQ(2-)) using the Cambridge Structural Database (CSD) along with dispersion-corrected density functional theory (DFT-D) calculations for a range of hydrogen-bonded dimers. The -OH and -C=O groups of H2SQ, HSQ(-) and SQ(2-) are potent donors and acceptors, as indicated by their hydrogen-bond geometries in available crystal structures in the CSD, and by the attractive energies calculated for their dimers with acetone and methanol, which were used as model acceptors and donors. The two anions have sufficient examples in the CSD for their addition as new central groups in IsoStar. It is also shown that charge- and resonance-assisted hydrogen bonds involving H2SQ and HSQ(-) are similar in strength to those made by carboxylate COO(-) acceptors, while hydrogen bonds made by the dianion SQ(2-) are somewhat stronger. The study reinforces the value of squaric acid and its anions as cocrystal formers and their actual and potential importance as isosteric replacements for carboxylic acid and carboxylate functions. PMID:24056361

  12. The epidemiology and burden of Alzheimer’s disease in Taiwan utilizing data from the National Health Insurance Research Database

    Directory of Open Access Journals (Sweden)

    Hung YN

    2016-08-01

    Full Text Available Yen-Ni Hung,1 Zbigniew Kadziola,2 Alan JM Brnabic,3 Ju-Fen Yeh,4 Jong-Ling Fuh,5,6 Jen-Ping Hwang,7,8 William Montgomery,9 1School of Gerontology Health Management and Master Program in Long-Term Care, College of Nursing, Taipei Medical University, Taipei, Taiwan, Republic of China; 2Real World Analytics, Eli Lilly GmbH, Vienna, Austria; 3Real World Analytics, Eli Lilly Australia Pty Ltd, West Ryde, NSW, Australia; 4Department of Medicine, Eli Lilly and Company, Taiwan, Republic of China; 5Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, 6Faculty of Medicine, School of Medicine, National Yang Ming University, 7Department of Psychiatry, Taipei Veterans General Hospital, 8Division of Psychiatry, School of Medicine, National Yang-Ming University, Taipei, Taiwan, Republic of China; 9Eli Lilly Australia Pty Ltd, West Ryde, NSW, Australia Purpose: The objectives of this study were to estimate the incidence, cumulative incidence, and economic burden of Alzheimer’s disease (AD in Taiwan, using data from the National Health Insurance Research Database (NHIRD.Materials and methods: This was a retrospective, longitudinal, observational study using data from the Longitudinal Health Insurance Database of the NHIRD. Patients were included in this study if they were 50 years of age or older and their records included a primary or secondary diagnosis of AD. New patients who met inclusion criteria were followed up longitudinally from 2005 to 2010. Costs were calculated for the first year following the diagnosis of AD.Results: Overall, a higher percentage of women than men were diagnosed with AD (54% vs 46%, respectively. The first AD diagnosis occurred most frequently in the age of 75–84 years. The person-year incidence rate increased from 5.63/1,000 persons (95% CI, 5.32–5.94 in 2005 to 8.17/1,000 persons (95% CI, 7.78–8.57 in 2010. The cumulative incidence rate was 33.54/1,000 persons (95% CI, 32.76–34.33 in 2005

  13. Research of the Occupational Psychological Impact Factors Based on the Frequent Item Mining of the Transactional Database

    Directory of Open Access Journals (Sweden)

    Cheng Dongmei

    2015-01-01

    Full Text Available Based on the massive reading of data mining and association rules mining documents, this paper will start from compressing transactional database and propose the frequent complementary item storage structure of the transactional database. According to the previous analysis, this paper will also study the association rules mining algorithm based on the frequent complementary item storage structure of the transactional database. At last, this paper will apply this mining algorithm in the test results analysis module of team psychological health assessment system, and will extract the relationship between each psychological impact factor, so as to provide certain guidance for psychologists in their mental illness treatment.

  14. Shark Mark Recapture Database (MRDBS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Shark Mark Recapture Database is a Cooperative Research Program database system used to keep multispecies mark-recapture information in a common format for...

  15. BioWarehouse: a bioinformatics database warehouse toolkit

    Directory of Open Access Journals (Sweden)

    Stringer-Calvert David WJ

    2006-03-01

    Full Text Available Abstract Background This article addresses the problem of interoperation of heterogeneous bioinformatics databases. Results We introduce BioWarehouse, an open source toolkit for constructing bioinformatics database warehouses using the MySQL and Oracle relational database managers. BioWarehouse integrates its component databases into a common representational framework within a single database management system, thus enabling multi-database queries using the Structured Query Language (SQL but also facilitating a variety of database integration tasks such as comparative analysis and data mining. BioWarehouse currently supports the integration of a pathway-centric set of databases including ENZYME, KEGG, and BioCyc, and in addition the UniProt, GenBank, NCBI Taxonomy, and CMR databases, and the Gene Ontology. Loader tools, written in the C and JAVA languages, parse and load these databases into a relational database schema. The loaders also apply a degree of semantic normalization to their respective source data, decreasing semantic heterogeneity. The schema supports the following bioinformatics datatypes: chemical compounds, biochemical reactions, metabolic pathways, proteins, genes, nucleic acid sequences, features on protein and nucleic-acid sequences, organisms, organism taxonomies, and controlled vocabularies. As an application example, we applied BioWarehouse to determine the fraction of biochemically characterized enzyme activities for which no sequences exist in the public sequence databases. The answer is that no sequence exists for 36% of enzyme activities for which EC numbers have been assigned. These gaps in sequence data significantly limit the accuracy of genome annotation and metabolic pathway prediction, and are a barrier for metabolic engineering. Complex queries of this type provide examples of the value of the data warehousing approach to bioinformatics research. Conclusion BioWarehouse embodies significant progress on the

  16. Database management research for the Human Genome Project: Progress report, 7/1/96-3/15/97

    Energy Technology Data Exchange (ETDEWEB)

    Goodman, N.

    1997-03-01

    Progress is reported on the development of software that works in conjunction with database management systems (DBMSs) in ways that are useful for genomics. This new release of LabBase has two major advantages over the previous version, namely it runs on the Sybase relational DBMS rather than ObjectStore and offers more complete data modeling features than the previous version so is suitable for more kinds of genetic databases.

  17. IVR RSA Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This database contains trip-level reports submitted by vessels participating in Research Set-Aside projects with IVR reporting requirements.

  18. Further Research is Required to Determine Which Database Products Best Support Research in Public Administration. A review of: Tucker, James, Corey. “Database Support for Research in Public Administration.” Behavioral & Social Sciences Librarian 24.1 (2005: 47-60.

    Directory of Open Access Journals (Sweden)

    David Hook

    2006-06-01

    Full Text Available Objective – To examine the extent to which six commercial database products support student and faculty research in the area of public administration. Design – Bibliometric study. Setting – Academic library in the United States. Subjects – Six commercial business‐related database products were examined: Proquest’s ABI/INFORM Global edition (ABI, EBSCO’s Business Source Premier (BSP, Gale’s General BusinessFile ASAP (GBF, EBSCO’s Academic Search Premier (ASP, EBSCO’s Expanded Academic Index (EAI and Proquest’s International Academic Research Library (ARL. Three of the databases (ABI, BSP, GBF were chosen because they address the management, human resource, and financing elements of public administration. The other three (ASP, EAI, ARL were included because of their multidisciplinary coverage. Methods – A list of journal titles covering public administration was assembled from the Institute of Scientific Information’s Social Sciences Citation Index and previously published lists of recommended journals in the field. The author then compared the compiled list of journal titles against the journal titles indexed by the six database products. He further analyzed the results by level of journal coverage (abstract only, full‐text, and full‐text with embargo and subject area based on categories described in Ulrich’s Periodicals Directory. Main Results – The study found that three of the six database products ‐‐EAI, BSP, and ARL ‐‐ provide indexing for the greatest number of public administration journals contained in the compiled list. EIA and ARL cover the greatest number of those that are full‐text journals, while BSP and ASP cover the greatest number of those full‐text journals limited by publisher embargoes. Conclusion – The author concludes that of the six databases examined, EAI, BSP, and ARL are the best for public administration research, based on their strength in the subject areas of public

  19. RESEARCH ON THE POLYCONDENSATION KINETICS OF ω-AMINO-ACIDS

    Institute of Scientific and Technical Information of China (English)

    WANG Baoren; SHI Manli; QIAN Chunqing

    1983-01-01

    In our previous report, it was discovered that the polycondensation of 9-amino-nonanoic acid follows second order from the beginning up to the extent of reaction, p, around 99%, and after which the reaction changes rapidly to third order. In this paper, we wish to report that this change of the reaction order from second to third occurred also in the polycondensation of 6aminocaproic acid and 11-amino-undecanoic acid. The transition region lay again at p around 99%.It may be concluded that this is a general rule in the polycondensation of the ω-amino-acids (monomers of the A-B type), and the controversial results that appeared in the literature may be cleared up by our experiments.

  20. Research on the Oracle Database Security and Security Strategy%Oracle数据库安全及安全策略研究

    Institute of Scientific and Technical Information of China (English)

    何子龙

    2015-01-01

    Oracle数据库是市场占有率第一的数据库,其安全问题关系到大部分公司业务数据的安全性、私密性、完整性。从权限管理、用户管理、审计控制、密码安全四方面研究Oracle数据库的安全问题,并针对安全问题进行安全策略优化。经过该安全策略加固方法的实施,可以解决大部分Oracle数据库安全问题,达到保障数据安全的目的。%Oracle database has the largest market share of the database market. Its security issues related to the security of the majority of the com-pany's business data, privacy, integrity. Researches on the security problem of Oracle database from four areas:security issue rights man-agement, user management, audit controls and password security. Also researches on security issues for security policy optimization. After implementation of this security policy reinforcement method can solve most of the Oracle database security issues to ensure data security.

  1. Research on Oracle database management for hospital%医院Oracle数据库安全管理研究

    Institute of Scientific and Technical Information of China (English)

    于京杰; 刘方斌; 马锡坤

    2013-01-01

    为了减少数据库故障的发生率、保障数据库稳定运行、为医务工作人员和患者提供正确有效的数据信息,文中阐述了医院Oracle数据库管理存在的问题,并从数据库使用制度、备份管理、数据库审计等3个方面分析了数据库安全管理,给出了相应的数据库安全管理策略.实际应用表明,本文的安全策略大幅提升了医院Oracle数据库的安全性.%In order to reduce the failure rate, guarantee database stable operation, provide correct and effective information for medical staff and patients, the paper explains the problems of Oracle database management, and analyses Oracle database security management from the fair use system, database backup and audit, then gives the corresponding strategies. The practical application shows that the security strategies improve the hospital Oracle database security greatly.

  2. 基于数据库安全的研究与应用%Research and Application of Database Security

    Institute of Scientific and Technical Information of China (English)

    葛耀武; 张明玉; 方芳

    2014-01-01

    With the rapid development of computer technology and communication technology, big data era has arrived. To follow the era demand, the database technology provides the solution. The database as the aggregates of information, it shoulders the task of storing and managing data, and its security is also becoming increasingly important. This article discusses the definition of database and the security threat faced by database system, and discusses the database-related security technology.%伴随着计算机技术以及通信技术的快速发展,大数据时代已经来临。而数据库技术为顺应这一时代要求提供了方案,数据库作为信息的聚集体,担负着存储和管理数据信息的任务,其安全性也越来越重要。本文论述了数据库安全定义、数据库系统面临的安全威胁,探讨了数据库相关的安全技术。

  3. Oracle Database Query Optimization Analysis and Research%Oracle数据库查询优化分析与研究

    Institute of Scientific and Technical Information of China (English)

    孙静

    2011-01-01

    Oracle database system optimized for the normal operation of the system plays a vital role,and database query operations that affect the response time of an application system,a key factor.This paper describes the target Oracle database performance tuning%Oracle数据库系统的优化对于整个系统的正常运行起着至关重要的作用,而数据库的查询操作是影响一个应用系统响应时间的关键因素。本文主要介绍Oracle数据库性能优化的目标、提高sQL语句查询优化的措施与方法研究这两方面的内容。

  4. Database Manager

    Science.gov (United States)

    Martin, Andrew

    2010-01-01

    It is normal practice today for organizations to store large quantities of records of related information as computer-based files or databases. Purposeful information is retrieved by performing queries on the data sets. The purpose of DATABASE MANAGER is to communicate to students the method by which the computer performs these queries. This…

  5. Research on thin grid materials of lead-acid batteries

    Institute of Scientific and Technical Information of China (English)

    WANG Erdong; SHI Pengfei; GAO Jun

    2006-01-01

    A detailed investigation on Pb-Ca-Sn alloys was made in order to choose suitable grid alloys materials for thin plate lead-acid batteries. The electrochemical performances of alloys were investigated by electrochemical corrosion experiment, scanning electron microscope (SEM), and cyclic voltammetry (CV) test. The results indicate that Pb-Ca-Sn-Bi-Cu alloys can be used to make the grids used for thin grid lead-acid batteries, the content of bismuth has primaryeffects on the corrosion resistance of grid alloys, the composition of alloys plays an important role on batteries performance, and appropriate scale of elements can be choosed to obtain optimal electrochemical performance. The lead-acid batteries using this kind of grid show good performance by cycle life test.

  6. Research on Arachidonic Acid and Eicosapentaenoic Acid Anabolic Metabolism in Diasporangium sp.

    Institute of Scientific and Technical Information of China (English)

    DAI Chuan-chao; XU Yu-fen; XIA Shun-xiang; ZHAO Mo; YE Yu-cheng

    2010-01-01

    The fatty acids of a strain of Diasporangium sp.had been analyzed by using GC-MS.The fatty acids of twenty mutants were determined.Based on these results,the producing of eicosapentaenoic acid(EPA)supposed via 18∶2,18∶3,20∶3,20∶4 which all belong to ω-6 fatty acids.The ω-3 desaturation was undertaken at arachidonic acid(AA).In addition,mutant strains resulted in enhanced content of AA which could get two times more than initial strain,but no compact on EPA.

  7. Data Extraction and Management in Networks of Observational Health Care Databases for Scientific Research: A Comparison of EU-ADR, OMOP, Mini-Sentinel and MATRICE Strategies

    OpenAIRE

    Gini, Rosa; Schuemie, Martijn; Brown, Jeffrey; Ryan, Patrick; Vacchi, Edoardo; Coppola, Massimo; Cazzola, Walter; Coloma, Preciosa; Berni, Roberto; Diallo, Gayo; Oliveira, José Luis; Avillach, Paul; Trifirò, Gianluca; Rijnbeek, Peter; Bellentani, Mariadonata

    2016-01-01

    Introduction: We see increased use of existing observational data in order to achieve fast and transparent production of empirical evidence in health care research. Multiple databases are often used to increase power, to assess rare exposures or outcomes, or to study diverse populations. For privacy and sociological reasons, original data on individual subjects can’t be shared, requiring a distributed network approach where data processing is performed prior to data sharing. Case Descriptions...

  8. Oracle数据库的性能优化方法研究%Oracle Database Performance Optimization Method Research

    Institute of Scientific and Technical Information of China (English)

    罗瑞明

    2012-01-01

    Due to the hardware, operating system, application program and parameters and other reasons, the performance of the database after running for a period of time will decrease. The database system performance optimization is a important means to guarantee their normal operation. This article from the SQL statement, CPU adjustment, disk I / O, memory allocation and network system from several aspects, for the Oracle database to carry on the thorough analysis, and put forward the optimization strategies to ensure efficient operation of Oracle database system and provide useful reference.%由于硬件、操作系统、应用程序以及参数等方面的原因,数据库的性能在运行一段时间后都会下降。对数据库系统性能进行优化,是保证其正常运行的重要手段。文章从SQL语句、CPU调整、磁盘I/O、内存分配和系统网络几个方面出发,对Oracle数据库进行了深入分析,并提出性能优化策略,从而为保障Oracle数据库系统高效地运行,提供具有实际应用价值的参考。

  9. Database Replication

    CERN Document Server

    Kemme, Bettina

    2010-01-01

    Database replication is widely used for fault-tolerance, scalability and performance. The failure of one database replica does not stop the system from working as available replicas can take over the tasks of the failed replica. Scalability can be achieved by distributing the load across all replicas, and adding new replicas should the load increase. Finally, database replication can provide fast local access, even if clients are geographically distributed clients, if data copies are located close to clients. Despite its advantages, replication is not a straightforward technique to apply, and

  10. Probabilistic Databases

    CERN Document Server

    Suciu, Dan; Koch, Christop

    2011-01-01

    Probabilistic databases are databases where the value of some attributes or the presence of some records are uncertain and known only with some probability. Applications in many areas such as information extraction, RFID and scientific data management, data cleaning, data integration, and financial risk assessment produce large volumes of uncertain data, which are best modeled and processed by a probabilistic database. This book presents the state of the art in representation formalisms and query processing techniques for probabilistic data. It starts by discussing the basic principles for rep

  11. SHORT SURVEY ON GRAPHICAL DATABASE

    Directory of Open Access Journals (Sweden)

    Harsha R Vyavahare

    2015-08-01

    Full Text Available This paper explores the features of graph databases and data models. The popularity towards work with graph models and datasets has been increased in the recent decades .Graph database has a number of advantage over the relational database. This paper take a short review on the graph and hyper graph concepts from mathematics so that graph so that we can understand the existing difficulties in the implantation of graph model. From the Past few decades saw hundreds of research contributions their vast research in the DBS field with graph database. However, the research on the existence of general purpose DBS managements and mining that suits for variety of applications is still very much active. The review is done based on the Application of graph model techniques in the database within the framework of graph based approaches with the aim of implementation of different graphical database and tabular database

  12. Research of Sichuan Paocai and Lactic Acid Bacteria

    OpenAIRE

    Chen Gong; Yu Wen-Hua; Zhang Qi-sheng; Song Ping; Zhang Bei-Bei; Liu Zhu; You Jing-gang; Li Heng

    2014-01-01

    Sichuan Paocai with long history is a typical representative of Chinese pickles, which has been inherited for thousands years. Its strong vitality was largely due to its unique microbial fermentation style. In this study, molecular microbial technology and traditional microbial technology were employed to study the distributions and changes of the microorganisms during the fermentation. The results showed that the lactic acid bacteria such as Leuconostoc mesenteroides, Lactobacillus plantarum...

  13. Dealer Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The dealer reporting databases contain the primary data reported by federally permitted seafood dealers in the northeast. Electronic reporting was implemented May...

  14. National database

    DEFF Research Database (Denmark)

    Kristensen, Helen Grundtvig; Stjernø, Henrik

    1995-01-01

    Artikel om national database for sygeplejeforskning oprettet på Dansk Institut for Sundheds- og Sygeplejeforskning. Det er målet med databasen at samle viden om forsknings- og udviklingsaktiviteter inden for sygeplejen.......Artikel om national database for sygeplejeforskning oprettet på Dansk Institut for Sundheds- og Sygeplejeforskning. Det er målet med databasen at samle viden om forsknings- og udviklingsaktiviteter inden for sygeplejen....

  15. STATE ACID RAIN RESEARCH AND SCREENING SYSTEM - VERSION 1.0 USER'S MANUAL

    Science.gov (United States)

    The report is a user's manual that describes Version 1.0 of EPA's STate Acid Rain Research and Screening System (STARRSS), developed to assist utility regulatory commissions in reviewing utility acid rain compliance plans. It is a screening tool that is based on scenario analysis...

  16. Development of a database for prompt gamma-ray neutron activation analysis: Summary report of the third research coordination meeting

    Energy Technology Data Exchange (ETDEWEB)

    Lindstrom, Richard M.; Firestone, Richard B.; Pavi, ???

    2003-04-01

    The main discussions and conclusions from the Third Co-ordination Meeting on the Development of a Database for Prompt Gamma-ray Neutron Activation Analysis are summarized in this report. All results were reviewed in detail, and the final version of the TECDOC and the corresponding software were agreed upon and approved for preparation. Actions were formulated with the aim of completing the final version of the TECDOC and associated software by May 2003.

  17. A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology

    Directory of Open Access Journals (Sweden)

    Huang Xiangning

    2001-02-01

    Full Text Available Abstract Background An association between mumps-measles-rubella (MMR vaccination and the onset of symptoms typical of autism has recently been suggested. This has led to considerable concern about the safety of the vaccine. Methods A matched case-control study using data derived form the United Kingdom General Practice Research Database. Children with a possible diagnosis of autism will be identified from their electronic health records. All diagnoses will be validated by a detailed review of hospital letters and by using information derived from a parental questionnaire. Ten controls per case will be selected from the database. Conditional logistic regression will be used to assess the association between MMR vaccination and autism. In addition case series analyses will be undertaken to estimate the relative incidence of onset of autism in defined time intervals after vaccination. The study is funded by the United Kingdom Medical Research Council. Discussion Electronic health databases offer tremendous opportunities for evaluating the adverse effects of vaccines. However there is much scope for bias and confounding. The rigorous validation of all diagnoses and the collection of additional information by parental questionnaire in this study are essential to minimise the possibility of misleading results.

  18. Treatment Options for GERD or Acid Reflux Disease: A Review of the Research for Adults

    Science.gov (United States)

    Treatment Options for GERD or Acid Reflux Disease A Review of the Research for Adults Is This Information Right for Me? Yes, if: A doctor said that you have gastroesophageal reflux disease (GERD), a chronic disease that causes ongoing ...

  19. The CHROMEVALOA Database: A Resource for the Evaluation of Okadaic Acid Contamination in the Marine Environment Based on the Chromatin-Associated Transcriptome of the Mussel Mytilus galloprovincialis

    Directory of Open Access Journals (Sweden)

    José M. Eirín-López

    2013-03-01

    Full Text Available Okadaic Acid (OA constitutes the main active principle in Diarrhetic Shellfish Poisoning (DSP toxins produced during Harmful Algal Blooms (HABs, representing a serious threat for human consumers of edible shellfish. Furthermore, OA conveys critical deleterious effects for marine organisms due to its genotoxic potential. Many efforts have been dedicated to OA biomonitoring during the last three decades. However, it is only now with the current availability of detailed molecular information on DNA organization and the mechanisms involved in the maintenance of genome integrity, that a new arena starts opening up for the study of OA contamination. In the present work we address the links between OA genotoxicity and chromatin by combining Next Generation Sequencing (NGS technologies and bioinformatics. To this end, we introduce CHROMEVALOAdb, a public database containing the chromatin-associated transcriptome of the mussel Mytilus galloprovincialis (a sentinel model organism in response to OA exposure. This resource constitutes a leap forward for the development of chromatin-based biomarkers, paving the road towards the generation of powerful and sensitive tests for the detection and evaluation of the genotoxic effects of OA in coastal areas.

  20. [Research progress and application prospect of near-infrared spectroscopy in analysis of food amino acid].

    Science.gov (United States)

    Yu, Xiao-Lan; Xu, Ning; He, Yong

    2014-09-01

    To investigate the progress and application of near infrared spectroscopy (NIR) used to detect amino acids in the growth of crops and food processing process. With online searching databases including ISI (Web of Knowledge), CNKI (China Knowledge Network), summarize the detection of chemical value using high performance liquid chromatography (HPLC) and chemometric methods involved in the application of NIR used to analyze amino acids in food, meanwhile summarize the data, materials and main topics in relevant original literature. Overview the methods of chemical value detection using HPLC and chemometric analysis, their applications in detecting the quality of crops, determining the content of water, amino acids and polyphenol in green tea, detecting the quality of feed and determining the content of amino acids in cheese, ham and meat products, We forecasted the application of NIR in determining the content of amino acids in food and analyzed its merits and drawbacks. The development of NIR's application in amino acids detection should be based on the HPLC detection, and the problem of model transfer mainly restricts its large-scale promotion currently. Online analysis can monitor the entire reaction and change process from raw materials to products and thus meets the needs of real-time monitoring food quality from production to sales, and it will be an important direction for future.

  1. Specialist Bibliographic Databases.

    Science.gov (United States)

    Gasparyan, Armen Yuri; Yessirkepov, Marlen; Voronov, Alexander A; Trukhachev, Vladimir I; Kostyukova, Elena I; Gerasimov, Alexey N; Kitas, George D

    2016-05-01

    Specialist bibliographic databases offer essential online tools for researchers and authors who work on specific subjects and perform comprehensive and systematic syntheses of evidence. This article presents examples of the established specialist databases, which may be of interest to those engaged in multidisciplinary science communication. Access to most specialist databases is through subscription schemes and membership in professional associations. Several aggregators of information and database vendors, such as EBSCOhost and ProQuest, facilitate advanced searches supported by specialist keyword thesauri. Searches of items through specialist databases are complementary to those through multidisciplinary research platforms, such as PubMed, Web of Science, and Google Scholar. Familiarizing with the functional characteristics of biomedical and nonbiomedical bibliographic search tools is mandatory for researchers, authors, editors, and publishers. The database users are offered updates of the indexed journal lists, abstracts, author profiles, and links to other metadata. Editors and publishers may find particularly useful source selection criteria and apply for coverage of their peer-reviewed journals and grey literature sources. These criteria are aimed at accepting relevant sources with established editorial policies and quality controls. PMID:27134485

  2. The Stanford Tissue Microarray Database.

    Science.gov (United States)

    Marinelli, Robert J; Montgomery, Kelli; Liu, Chih Long; Shah, Nigam H; Prapong, Wijan; Nitzberg, Michael; Zachariah, Zachariah K; Sherlock, Gavin J; Natkunam, Yasodha; West, Robert B; van de Rijn, Matt; Brown, Patrick O; Ball, Catherine A

    2008-01-01

    The Stanford Tissue Microarray Database (TMAD; http://tma.stanford.edu) is a public resource for disseminating annotated tissue images and associated expression data. Stanford University pathologists, researchers and their collaborators worldwide use TMAD for designing, viewing, scoring and analyzing their tissue microarrays. The use of tissue microarrays allows hundreds of human tissue cores to be simultaneously probed by antibodies to detect protein abundance (Immunohistochemistry; IHC), or by labeled nucleic acids (in situ hybridization; ISH) to detect transcript abundance. TMAD archives multi-wavelength fluorescence and bright-field images of tissue microarrays for scoring and analysis. As of July 2007, TMAD contained 205 161 images archiving 349 distinct probes on 1488 tissue microarray slides. Of these, 31 306 images for 68 probes on 125 slides have been released to the public. To date, 12 publications have been based on these raw public data. TMAD incorporates the NCI Thesaurus ontology for searching tissues in the cancer domain. Image processing researchers can extract images and scores for training and testing classification algorithms. The production server uses the Apache HTTP Server, Oracle Database and Perl application code. Source code is available to interested researchers under a no-cost license. PMID:17989087

  3. Web与数据库接口技术研究%Research on Interface Technology Between Web and Database

    Institute of Scientific and Technical Information of China (English)

    颜端武

    2000-01-01

    Web与数据库的结合是目前web技术和数据库技术发展的主流方向.本文通过对B/S体系结构的分析,对当前比较流行的几种接口技术进行了研究和分析,主要包括;CGI(Common Gateway Interface)技术、Web API(Appllcation Programming Interface)技术、JDBC(Java DataBase Connection)技术和ASP(Acrive Server Pages)技术.

  4. Navigating public microarray databases.

    Science.gov (United States)

    Penkett, Christopher J; Bähler, Jürg

    2004-01-01

    With the ever-escalating amount of data being produced by genome-wide microarray studies, it is of increasing importance that these data are captured in public databases so that researchers can use this information to complement and enhance their own studies. Many groups have set up databases of expression data, ranging from large repositories, which are designed to comprehensively capture all published data, through to more specialized databases. The public repositories, such as ArrayExpress at the European Bioinformatics Institute contain complete datasets in raw format in addition to processed data, whilst the specialist databases tend to provide downstream analysis of normalized data from more focused studies and data sources. Here we provide a guide to the use of these public microarray resources. PMID:18629145

  5. A Multidimensional Rasch Analysis of the Functional Independence Measure Based on the National Institute on Disability, Independent Living, and Rehabilitation Research Traumatic Brain Injury Model Systems National Database.

    Science.gov (United States)

    Pretz, Christopher R; Kean, Jacob; Heinemann, Allen W; Kozlowski, Allan J; Bode, Rita K; Gebhardt, Eveline

    2016-07-15

    A number of studies have evaluated the psychometric properties of the Functional Independence Measure (FIM™) using Rasch analysis, although none has done so using the National Institute on Disability, Independent Living, and Rehabilitation Research Traumatic Brain Injury Model Systems National Database, a longitudinal database that captures demographic and outcome information on persons with moderate to severe traumatic brain injury across the United States. In the current study, we examine the psychometric properties of the FIM as represented by persons within this database and demonstrate that the FIM comprises three subscales representing cognitive, self-care, and mobility domains. These subscales were analyzed simultaneously using a multivariate Rasch model in combination with a time dependent concurrent calibration scheme with the goal of creating a raw score-to-logit transformation that can be used to improve the accuracy of parametric statistical analyses. The bowel and bladder function items were removed because of misfit with the motor and cognitive items. Some motor items exhibited step disorder, which was addressed by collapsing Categories 1-3 for Toileting, Stairs, Locomotion, Tub/Shower Transfers; Categories 1 and 2 for Toilet and Bed Transfers; and Categories 2 and 3 for Grooming. The strong correlations (r = 0.82-0.96) among the three subscales suggest they should be modeled together. Coefficient alpha of 0.98 indicates high internal consistency. Keyform maps are provided to enhance clinical interpretation and application of study results.

  6. A Multidimensional Rasch Analysis of the Functional Independence Measure Based on the National Institute on Disability, Independent Living, and Rehabilitation Research Traumatic Brain Injury Model Systems National Database.

    Science.gov (United States)

    Pretz, Christopher R; Kean, Jacob; Heinemann, Allen W; Kozlowski, Allan J; Bode, Rita K; Gebhardt, Eveline

    2016-07-15

    A number of studies have evaluated the psychometric properties of the Functional Independence Measure (FIM™) using Rasch analysis, although none has done so using the National Institute on Disability, Independent Living, and Rehabilitation Research Traumatic Brain Injury Model Systems National Database, a longitudinal database that captures demographic and outcome information on persons with moderate to severe traumatic brain injury across the United States. In the current study, we examine the psychometric properties of the FIM as represented by persons within this database and demonstrate that the FIM comprises three subscales representing cognitive, self-care, and mobility domains. These subscales were analyzed simultaneously using a multivariate Rasch model in combination with a time dependent concurrent calibration scheme with the goal of creating a raw score-to-logit transformation that can be used to improve the accuracy of parametric statistical analyses. The bowel and bladder function items were removed because of misfit with the motor and cognitive items. Some motor items exhibited step disorder, which was addressed by collapsing Categories 1-3 for Toileting, Stairs, Locomotion, Tub/Shower Transfers; Categories 1 and 2 for Toilet and Bed Transfers; and Categories 2 and 3 for Grooming. The strong correlations (r = 0.82-0.96) among the three subscales suggest they should be modeled together. Coefficient alpha of 0.98 indicates high internal consistency. Keyform maps are provided to enhance clinical interpretation and application of study results. PMID:26559881

  7. WMC Database Evaluation. Case Study Report

    Energy Technology Data Exchange (ETDEWEB)

    Palounek, Andrea P. T [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-10-29

    The WMC Database is ultimately envisioned to hold a collection of experimental data, design information, and information from computational models. This project was a first attempt at using the Database to access experimental data and extract information from it. This evaluation shows that the Database concept is sound and robust, and that the Database, once fully populated, should remain eminently usable for future researchers.

  8. Distributed Databases Management Using Replication Method

    OpenAIRE

    Mircea Petrini

    2009-01-01

    Over the last several years, research into fully distributed database has slowly but surely found its way into commercial products. Today, many of the mainstream enterprise database products offer at least some level of transparent distributed database access. This paper studies the replication method as a component of the distributed databases management.

  9. Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study

    Directory of Open Access Journals (Sweden)

    Charlton Judith

    2011-05-01

    Full Text Available Abstract Background The purpose of this research is to develop and evaluate methods for conducting cluster randomised trials in a primary care database that contains electronic patient records for large numbers of family practices. Cluster randomised trials are trials in which the units allocated represent groups of individuals, in this case family practices and their registered patients. Cluster randomised trials often suffer from the limitation that they include too few clusters, leading to problems of insufficient power and only imprecise estimation of the intraclass correlation coefficient, a key design parameter. This difficulty might be overcome by utilising databases that already hold electronic patient records for large numbers of practices. The protocol describes one application: a study of antibiotic prescribing for acute respiratory infection; a second protocol outlines an intervention in a less frequent chronic condition of public health importance, stroke. Methods/Design The objective of the study is to implement a cluster randomised trial to test the effectiveness of an electronic record-based intervention at achieving a reduction in antibiotic prescribing at consultations for respiratory illness in patients aged 18 and 59 years old in intervention family practices as compared with controls. Family practices will be recruited from the practices that presently contribute data to the UK General Practice Research Database (GPRD. Following randomisation, electronic prompts will be installed remotely at intervention practices to promote adherence with evidence-based standards of medical practice. The intervention was developed through qualitative research at non-intervention practices. Data for outcome assessment will be obtained from anonymised electronic patient records that are routinely collected into GPRD. This protocol outlines the proposed study designs, data sources, sample size requirements, analysis methods and dissemination

  10. Bibliometric analysis of nutrition and dietetics research activity in Arab countries using ISI Web of Science database

    OpenAIRE

    Sweileh, Waleed M; Al-Jabi, Samah W.; Ansam F Sawalha; Zyoud, Sa’ed H

    2014-01-01

    Reducing nutrition-related health problems in Arab countries requires an understanding of the performance of Arab countries in the field of nutrition and dietetics research. Assessment of research activity from a particular country or region could be achieved through bibliometric analysis. This study was carried out to investigate research activity in “nutrition and dietetics” in Arab countries. Original and review articles published from Arab countries in “nutrition and dietetics” Web of Sci...

  11. License - Gclust Server | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available le of the data from this database. 2. When you conduct research by using this dat...abase, and describe the research results in an article or paper, you always need to cite this database, and

  12. Challenges of molecular nutrition research 6: The nutritional phenotype database to store, share and evaluate nutritional systems biology studies

    NARCIS (Netherlands)

    Ommen, B. van; Bouwman, J.; Dragsted, L.O.; Drevon, C.A.; Elliott, R.; Groot, P. de; Kaput, J.; Mathers, J.C.; Müller, M.; Pepping, F.; Saito, J.; Scalbert, A.; Radonjic, M.; Rocca-Serra, P.; Travis, A.; Wopereis, S.; Evelo, C.T.

    2010-01-01

    The challenge of modern nutrition and health research is to identify food-based strategies promoting life-long optimal health and well-being. This research is complex because it exploits a multitude of bioactive compounds acting on an extensive network of interacting processes. Whereas nutrition res

  13. Development of a dish-based, semi-quantitative FFQ for the Korean diet and cancer research using a database approach.

    Science.gov (United States)

    Park, Min Kyung; Kim, Dong Woo; Kim, Jeongseon; Park, Sohee; Joung, Hyojee; Song, Won O; Paik, Hee Young

    2011-04-01

    We used a database approach in developing a dish-based, semi-quantitative FFQ for Korean diet and cancer research. Cancer-related dietary factors (CRDF) recognised in the scientific community and dietary intake data from the 2001 Korean National Health and Nutrition Examination Survey and the 2002 Korean National Nutrition Survey by Season were used. The list of dishes (n 993) was those reported to be consumed by individuals over 30 years of age during all four seasons. The resulting 112-dish list was selected using contribution analyses and variability analyses to detect between-person variation for CRDF and non-CRDF nutrients. Variations of each dish were grouped into one dish for the final list of 112 dishes, which were then linked to the nutrient database. The final 112 dish items consisted of nine Korean staple dishes, including rice and noodles, twenty-five soups and stews, fifty-four side dishes, nine beverages, nine fruit dishes and six alcoholic beverages. The percentage coverages of energy, protein, fat, carbohydrate and alcohol intake in the selected 112 dishes were 82·4, 76·4, 68·9, 86·0 and 99·8 %, respectively. Dietary exposure to cancer-related Korean dietary factors can be assessed by this new dish-based, semi-quantitative FFQ. This new instrument can calculate the intake of CRDF along with non-CRDF nutrient intake for cancer research. PMID:21092384

  14. Food traceability systems in China: The current status of and future perspectives on food supply chain databases, legal support, and technological research and support for food safety regulation.

    Science.gov (United States)

    Tang, Qi; Li, Jiajia; Sun, Mei; Lv, Jun; Gai, Ruoyan; Mei, Lin; Xu, Lingzhong

    2015-02-01

    Over the past few decades, the field of food security has witnessed numerous problems and incidents that have garnered public attention. Given this serious situation, the food traceability system (FTS) has become part of the expanding food safety continuum to reduce the risk of food safety problems. This article reviews a great deal of the related literature and results from previous studies of FTS to corroborate this contention. This article describes the development and benefits of FTS in developed countries like the United States of America (USA), Japan, and some European countries. Problems with existing FTS in China are noted, including a lack of a complete database, inadequate laws and regulations, and lagging technological research into FTS. This article puts forward several suggestions for the future, including improvement of information websites, clarification of regulatory responsibilities, and promotion of technological research.

  15. Creation of a dynamic database and analysis of LIDAR measurements in web format at the Laboratory of Environmental Laser Applications at the Nuclear and Energy Research Institute

    International Nuclear Information System (INIS)

    The LIDAR system (Light Detection and Ranging) laser remote sensing at the Nuclear and Energy Research Institute - Laboratory of Environmental Laser Applications allows on line measurements of variations in the concentrations of atmospheric aerosols by sending a laser beam to the atmosphere and collecting the backscattered light. Such a system supplies a great number of physical parameters that must be managed in an agile form to the attainment of a real time analysis. Database implementation therefore becomes an important toll of communication and graphical visualization of measurements. A criterion for classification of this valuable information was adopted, establishing defined levels of storage from specific characteristics of the determined data types. The compilation and automation of these measurements will promote optimized integration between data, analysis and retrieval of the resulting properties and of the atmosphere, improving future research and data analysis. (author)

  16. Databases and data mining

    Science.gov (United States)

    Over the course of the past decade, the breadth of information that is made available through online resources for plant biology has increased astronomically, as have the interconnectedness among databases, online tools, and methods of data acquisition and analysis. For maize researchers, the numbe...

  17. Research of Database Based on NoSQL%基于NoSQL的数据库技术分析

    Institute of Scientific and Technical Information of China (English)

    权治; 宋晶晶

    2013-01-01

    由于Web2.0的快速发展,非关系型、分布式数据存储得到了快速的发展.针对传统关系型数据库逐渐暴露出的性能瓶颈,介绍了非关系型数据库(Non_ relational Database,NoSQL)模型及NoSQL数据库,对NoSQL数据库具有的特点做了简单定义,阐述了NoSQL数据库的存储方式,论证了NoSQL比较于传统关系数据库的优点,并介绍了著名的CAP理论.针对NoSQL的大数据量存储机制,总结了主流解决方案的共同特点及共同技术,并对数据库的性能测试结果进行了分析.

  18. Biological Databases for Behavioral Neurobiology

    OpenAIRE

    Baker, Erich J

    2012-01-01

    Databases are, at their core, abstractions of data and their intentionally derived relationships. They serve as a central organizing metaphor and repository, supporting or augmenting nearly all bioinformatics. Behavioral domains provide a unique stage for contemporary databases, as research in this area spans diverse data types, locations, and data relationships. This chapter provides foundational information on the diversity and prevalence of databases, how data structures support the variou...

  19. SHORT SURVEY ON GRAPHICAL DATABASE

    OpenAIRE

    Harsha R Vyavahare; Dr.P.P.Karde

    2015-01-01

    This paper explores the features of graph databases and data models. The popularity towards work with graph models and datasets has been increased in the recent decades .Graph database has a number of advantage over the relational database. This paper take a short review on the graph and hyper graph concepts from mathematics so that graph so that we can understand the existing difficulties in the implantation of graph model. From the Past few decades saw hundreds of research contributions the...

  20. Asian Agricultural Research is indexed by CABI, CSA Illumina, AGE and other famous databases in many countries

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers, Asian Agricultural Research eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as one of the most

  1. Development of a Cost-Effective Database Software for Psychiatric Research: A Study From Tertiary Care Teaching Hospital

    OpenAIRE

    Sabu Karakkamandapam; Narayanan Sree Kumaran Nair; PSVN Sharma

    2010-01-01

    Background: Technological progression made drastic changes in health care. Still there is a growing concern about proper utilization of health information within hospitals for various research activities. Huge volumes of such health information in majority of hospitals are redundant due to lack of appropriate and cost-effective technological tools for retrieving relevant health information for research purpose. Objective: To develop a cost-effective and user-friendly computerized medical reco...

  2. Research of Database Monitoring and Management Technology in Multi-database System Environment%多数据库系统环境数据库监控与管理技术研究

    Institute of Scientific and Technical Information of China (English)

    吴明礼; 杨小燕; 李也白

    2015-01-01

    针对多数据库系统环境数据库的集中监控与管理,设计一个多数据库系统的监控方案,通过读取系统表、系统视图以及执行脚本等方法实现对数据库DBMS、表空间和死锁的监控,并给出预警设置,当数据库指标超过规定指标时,以颜色预警提示或者以发邮件的形式提示报警。通过创建DBLINK来连接多个数据库,以实现对多个位于不同数据库服务器上的数据库系统进行监控。%For centralized monitoring and management of multi-database environment, design a multi-database system monitoring program. To achieve control of the database DBMS, table space and deadlocks by reading the system tables, system views, and execute scripts and other methods, when the database when the index exceeds the index to color warning prompt or in the form of e-mail prompt alarm. By creating DBLINK to connect multiple databases, in order to achieve a plurality of database systems located on different database servers to be monitored.

  3. MMI Face Database

    OpenAIRE

    Maat, L.M.; Sondak, R.C.; Valstar, M.F.; Pantic, M.; Gaia, P.

    2005-01-01

    The automatic recognition of human facial expressions is an interesting research area in AI with a growing number of projects and researchers. In spite of repeated references to the need for a reference set of images that could provide a basis for benchmarking various techniques in automatic facial expression analysis, a readily accessible and complete enough database of face images does not exist yet. This lack represented our main incentive to develop a web-based, easily accessible, and eas...

  4. Performance analysis of in memory databases

    OpenAIRE

    Škarabot, Rene

    2014-01-01

    The choice of the appropriate database type presents an important factor in any project development. On account of their data access speed, memory databases have gradually gained ground against the formerly predominant standard disk databases. Since the majority of significant memory databases support the ACID properties, data loss is prevented even in case of power failure; hence their growing popularity. The thesis will examine and measure the extent to which, in performance, memory data...

  5. Semantic web services for web databases

    CERN Document Server

    Ouzzani, Mourad

    2011-01-01

    Semantic Web Services for Web Databases introduces an end-to-end framework for querying Web databases using novel Web service querying techniques. This includes a detailed framework for the query infrastructure for Web databases and services. Case studies are covered in the last section of this book. Semantic Web Services For Web Databases is designed for practitioners and researchers focused on service-oriented computing and Web databases.

  6. License - Open TG-GATEs Pathological Image Database | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available nse when distributing any derivative work based on part of whole of the data from this database. 2. When you conduct research... by using this database, and describe the research results in an

  7. A Molecular Biology Database Digest

    OpenAIRE

    Bry, François; Kröger, Peer

    2000-01-01

    Computational Biology or Bioinformatics has been defined as the application of mathematical and Computer Science methods to solving problems in Molecular Biology that require large scale data, computation, and analysis [18]. As expected, Molecular Biology databases play an essential role in Computational Biology research and development. This paper introduces into current Molecular Biology databases, stressing data modeling, data acquisition, data retrieval, and the integration...

  8. Mouse genome database 2016.

    Science.gov (United States)

    Bult, Carol J; Eppig, Janan T; Blake, Judith A; Kadin, James A; Richardson, Joel E

    2016-01-01

    The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the primary community model organism database for the laboratory mouse and serves as the source for key biological reference data related to mouse genes, gene functions, phenotypes and disease models with a strong emphasis on the relationship of these data to human biology and disease. As the cost of genome-scale sequencing continues to decrease and new technologies for genome editing become widely adopted, the laboratory mouse is more important than ever as a model system for understanding the biological significance of human genetic variation and for advancing the basic research needed to support the emergence of genome-guided precision medicine. Recent enhancements to MGD include new graphical summaries of biological annotations for mouse genes, support for mobile access to the database, tools to support the annotation and analysis of sets of genes, and expanded support for comparative biology through the expansion of homology data.

  9. Causes and risk factors for death in systemic sclerosis : a study from the EULAR Scleroderma Trials and Research (EUSTAR) database

    NARCIS (Netherlands)

    Tyndall, Anthony J.; Bannert, Bettina; Vonk, Madelon; Airo, Paolo; Cozzi, Franco; Carreira, Patricia E.; Bancel, Dominique Farge; Allanore, Yannick; Mueller-Ladner, Ulf; Distler, Oliver; Iannone, Florenzo; Pellerito, Raffaele; Pileckyte, Margarita; Miniati, Irene; Ananieva, Lidia; Gurman, Alexandra Balbir; Damjanov, Nemanja; Mueller, Adelheid; Valentini, Gabriele; Riemekasten, Gabriela; Tikly, Mohammed; Hummers, Laura; Henriques, Maria J. S.; Caramaschi, Paola; Scheja, Agneta; Rozman, Blaz; Ton, Evelien; Kumanovics, Gabor; Coleiro, Bernard; Feierl, Eva; Szucs, Gabriella; Von Muehlen, Carlos Alberto; Riccieri, Valeria; Novak, Srdan; Chizzolini, Carlo; Kotulska, Anna; Denton, Christopher; Coelho, Paulo C.; Koetter, Ina; Simsek, Ismail; de la Pena Lefebvre, Paloma Garcia; Hachulla, Eric; Seibold, James R.; Rednic, Simona; Stork, Jiri; Morovic-Vergles, Jadranka; Walker, Ulrich A.

    2010-01-01

    Objectives To determine the causes and predictors of mortality in systemic sclerosis (SSc). Methods Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria and prospectively followed in the EULAR Scleroderma Trials and Research (EUSTAR) cohort were analysed. EUSTAR centre

  10. Asian Agricultural Research is indexed by CABI,CSA Illumina,AGE and other famous databases in many countries

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers, Asian Agricultural Research eventually passes the extremely strict appraisal, to be indexed by CABI’ s full text repository. CABI is globally acclaimed as one of the most author-itative and prestigious abstract data bases concerning agriculture and forestry.

  11. Asian Agricultural Research is indexed by CABI,CSA Illumina,AGE and other famous databases in many countries

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers, Asian Agricultural Research eventually passes the extremely strict appraisal, to be indexed by CABI’ s full text repository. CABI is globally acclaimed as one of the most authoritative and prestigious abstract data bases concerning agriculture and forestry.

  12. Asian Agricultural Research is indexed by CABI,CSA illumina,AGE and other famous databases in many countries

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers, Asian Agricultural Research eventually passes the extremely strict appraisal, to be indexed by CABI’ s full text repository. CABI is globally acclaimed as one of the most author-itative and prestigious

  13. Asian Agricultural Research is indexed by CABI, CSA Illumina, AGE and other famous databases in many countries

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Through the joint efforts of editorial staff and multitudinous readers, Asian Agricultural Research eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as one of the most authoritative and prestigious abstract data

  14. Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database.

    NARCIS (Netherlands)

    Tyndall, A.J.; Bannert, B.; Vonk, M.C.; Airo, P.; Cozzi, F.; Carreira, P.E.; Bancel, D.F.; Allanore, Y.; Muller-Ladner, U.; Distler, O.; Iannone, F.; Pellerito, R.; Pileckyte, M.; Miniati, I.; Ananieva, L.; Gurman, A.B.; Damjanov, N.; Mueller, A.; Valentini, G.; Riemekasten, G.; Tikly, M.; Hummers, L.; Henriques, M.J.; Caramaschi, P.; Scheja, A.; Rozman, B.; Ton, E.; Kumanovics, G.; Coleiro, B.; Feierl, E.; Szucs, G.; Muhlen, C.A. Von; Riccieri, V.; Novak, S.; Chizzolini, C.; Kotulska, A.; Denton, C.; Coelho, P.C.; Kotter, I.; Simsek, I.; Pena Lefebvre, P.G. de la; Hachulla, E.; Seibold, J.R.; Rednic, S.; Stork, J.; Morovic-Vergles, J.; Walker, U.A.

    2010-01-01

    OBJECTIVES: To determine the causes and predictors of mortality in systemic sclerosis (SSc). METHODS: Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria and prospectively followed in the EULAR Scleroderma Trials and Research (EUSTAR) cohort were analysed. EUSTAR cent

  15. Collaborative research between academia and industry using a large clinical trial database: a case study in Alzheimer's disease

    DEFF Research Database (Denmark)

    Jones, Roy; Wilkinson, David; Lopez, Oscar L;

    2011-01-01

    community because of concerns that commercial, rather than scientific, goals are the primary purpose of such endeavours. Thus, there are few examples of sustained collaboration between leading academic clinical researchers and industry professionals in a large-scale data mining project. We present here...

  16. 浅谈SQL Server数据库的特点和基本功能%Research of the Characteristics and Basic Functions of the SQL Server Database

    Institute of Scientific and Technical Information of China (English)

    闫旭

    2012-01-01

    数据库的实质为数据的集合,数据库是根据数据结构来组织、存储和管理数据的仓库.随着数据库技术的不断发展,其种类也在不断增多,出现了许多大型的数据库,主要包括:IBM 的 DB2、Oracle数据库、Informix数据库、Sybase数据库、Postgre SQL数据库、Access数据库、FoxPro数据库、INFOBANK数据库、MYSQL数据库、SQL Server数据库等等.而SQL Server数据库在众多的数据库中的应用是比较广泛的,因此,本文探索了SQL Server数据库的特点和基本功能.%The essence of the database is the collection of data. Database is a warehouse to organize, store and manage data based on data structure. With the continuous development of database technology, the types of databases are also increasing, many large databases have appeared, mainly including: IBM DB2, Oracle database, Informix database, Sybase database, Postgre SQL database, FoxPro database Access database, INFOBANK database, MYSQL database, SQL Server database, and so on. And in many of the databases, the application of SQL Server database is more extensive; therefore, this paper explores the characteristics and basic functions of the SQL Server database.

  17. Djeen (Database for Joomla!’s Extensible Engine): a research information management system for flexible multi-technology project administration

    Science.gov (United States)

    2013-01-01

    Background With the advance of post-genomic technologies, the need for tools to manage large scale data in biology becomes more pressing. This involves annotating and storing data securely, as well as granting permissions flexibly with several technologies (all array types, flow cytometry, proteomics) for collaborative work and data sharing. This task is not easily achieved with most systems available today. Findings We developed Djeen (Database for Joomla!’s Extensible Engine), a new Research Information Management System (RIMS) for collaborative projects. Djeen is a user-friendly application, designed to streamline data storage and annotation collaboratively. Its database model, kept simple, is compliant with most technologies and allows storing and managing of heterogeneous data with the same system. Advanced permissions are managed through different roles. Templates allow Minimum Information (MI) compliance. Conclusion Djeen allows managing project associated with heterogeneous data types while enforcing annotation integrity and minimum information. Projects are managed within a hierarchy and user permissions are finely-grained for each project, user and group. Djeen Component source code (version 1.5.1) and installation documentation are available under CeCILL license from http://sourceforge.net/projects/djeen/files and supplementary material. PMID:23742665

  18. But I've already had a healthy baby: folic acid formative research with Latina mothers.

    Science.gov (United States)

    Prue, Christine E; Flores, Alina L; Panissidi, Paula; Lira, Andrea

    2008-10-01

    Each year, approximately 3000 pregnancies in the United States are affected by neural tube defects (NTDs), serious birth defects of the brain and spine. Daily periconceptional consumption of folic acid can reduce the incidence of NTDs by 50%-70%. This study was designed to understand Latina mothers' folic acid awareness, knowledge, and behaviors and to capture their reactions to advertising concepts and draft educational materials. The goal of the materials was to increase folic acid consumption through the use of a daily multivitamin. This study presents three phases of research that led to the development of Spanish language print advertisements, posters, a brochure, and radio ads that promote folic acid consumption in a manner that addresses the needs of Latina mothers.

  19. But I've already had a healthy baby: folic acid formative research with Latina mothers.

    Science.gov (United States)

    Prue, Christine E; Flores, Alina L; Panissidi, Paula; Lira, Andrea

    2008-10-01

    Each year, approximately 3000 pregnancies in the United States are affected by neural tube defects (NTDs), serious birth defects of the brain and spine. Daily periconceptional consumption of folic acid can reduce the incidence of NTDs by 50%-70%. This study was designed to understand Latina mothers' folic acid awareness, knowledge, and behaviors and to capture their reactions to advertising concepts and draft educational materials. The goal of the materials was to increase folic acid consumption through the use of a daily multivitamin. This study presents three phases of research that led to the development of Spanish language print advertisements, posters, a brochure, and radio ads that promote folic acid consumption in a manner that addresses the needs of Latina mothers. PMID:18752460

  20. MongoDB数据库中Sharding技术应用研究%Application and Research on Sharding Technology in MongoDB Database

    Institute of Scientific and Technical Information of China (English)

    梁海

    2014-01-01

    非关系型数据库的出现,对于解决面向文档的超大规模和高并发的问题提供了卓有成效的解决方案。 MongoDB为了提高处理大数据量的性能,提供了分片集群的功能,支持自动分片和划分架构,可以利用它构建一个水平扩展的数据库集群系统,将数据库分表存储在各个Sharding节点上。文中在研究MongoDB特性的基础上,着重分析Sharding技术的应用,通过比较普通和分片这两种情况下的性能测试,提出使用MongoDB中的Sharding技术来解决随着数据量增加带来的数据库的读写性能和效率的问题。%The emergence of non-relational databases,provide the effective solutions for the problems of large scale and high concurrency oriented document. In order to improve the performance of processing large amounts of data,MongoDB provides the ability to patch clus-ters,supports automatic partitioning and divides a schema,can use it to build a horizontal extension of the database cluster system,the da-tabase tables are stored in the Sharding node. Based on research of MongoDB feature,focus on the application of Sharding,through com-paring normal and Sharding in both cases of performance testing,present to use the Sharding in MongoDB for solving the problems of da-tabase reading and writing performance and efficiency generated by data volumes increasing.

  1. Database Description - AT Atlas | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available [ Credits ] BLAST Search Image Search Home About Archive Update History Contact us AT Atlas... Database Description General information of database Database name AT Atlas Alternative name Advanced Technologies Atlas...sing protein biosynthesis. Database description AT Atlas will make you familiar with the accomplishments by ...research groups of Protein Production, Structural Analysis and Chemical Regulation in the Targeted Proteins Research Program. AT Atla...base Site Policy | Contact Us Database Description - AT Atlas | LSDB Archive ...

  2. Learning in constructivist environments: a research based on the acid-base subject

    Directory of Open Access Journals (Sweden)

    Vera Gouveia

    2004-08-01

    Full Text Available This communication intends to show as a constructivist environment permits a better learning of some concepts related to the acid-base subject, where generally students have some misconceptions at the beginning, as many researches had proved. Based on a long epistemological, psychological and educational reflection, supported by a wide bibliographical research and our own experience, we make some considerations about learning constructivist environments in the classroom, emphasising the cooperative work of students. In the second part, the effects produced in the teaching of the acid-base by such kind of environment are described, according a quasi-experimental study involving 52 students in their 10th year of education, distributed by two equivalent groups, taught by the same teacher. The results indicate clearly that the constructivist environment promoted a better learning of the acid-base subject, as well as improved the educational relationship in the classroom. Furthermore, the students developed positive attitudes regarding themselves and the others.

  3. An analysis of market development strategy of a point-of-sale solutions provider's market research database

    OpenAIRE

    Medina, Ahmed

    2007-01-01

    This paper is a strategic analysis of Vivonet Inc. and its restaurant performance-benchmarking tool ZATA. Vivonet is a Point of Sales (POS) systems provider for the hospitality and the retail industry. Its ZATA product captures POS and other related information from restaurants and allows the restaurants to compare their performance with restaurants in their market segment. With ZATA, Vivonet has the opportunity to extend beyond the POS systems segment and compete in the market research i...

  4. Development and research of shallow water ambient noise database%潜水环境噪声数据库设计与开发

    Institute of Scientific and Technical Information of China (English)

    方鹏

    2015-01-01

    随着人类水下活动和实验行为的增多,越来越多的应用需要借助水声探测技术和水声通信技术,而在潜水环境中,环境噪声是以上技术的重要制约因素。因而,了解相应海域的环境噪声特性并建立环境噪声数据库,将有助于该海域的航运、测绘、通信等水声技术的应用与发展。本文针对以上需求,提出一种噪声建模方法,并根据该方法设计和研究相应的潜水环境噪声数据库。实验证明本文提出的方法具有一定的可行性。%Along with the increase in human activities and underwater experimental behavior, more and more applications need to use acoustic detection technology and underwater acoustic communication technology, and in the diving environment, environmental noise is one of the important restriction factor to the technology above. Therefore, to understand the corresponding environmental noise characteristics of waters and establishing database of environmental noise, would help surveying and mapping, navigation, communication etc. with application and development of underwater acoustic technology. In view of the above requirements, this paper puts forward a kind of noise modeling method, and research the method of design and research the corresponding diving database of environmental noise. Finally this paper gives the experimental verification, and demonstrates that the proposed method has certain feasibility.

  5. 领域专家库系统构建研究1)%Research on Construction of Domain Expert Database System

    Institute of Scientific and Technical Information of China (English)

    杜晖; 邱均平

    2014-01-01

    领域专家库系统的建设是符合我国人才发展战略规划中“建设人才信息网络,评价人才与发现人才相结合”指导思想的重要应用研究。文中从特征描述、科学评价和关联聚合三个维度构建了一个通用的领域专家指标体系,并详细阐述了各指标的计算方法,然后在此基础上通过对学术数据库的信息采集、整理、分析与挖掘的自动化处理,筛选指定领域专家,智能识别其研究领域,从而构建领域专家库系统。特别是基于专家间的各种关联关系实现了对相关领域专家资源的深度聚合与可视化揭示,能够为科研工作者和科研管理部门提供相应的信息服务和决策支持。%Construction of domain expert information systems is an important application research, which that “talent information network should be built so as to combine the evaluation of talents, is in align with the statement in China s strategic plan for talent development, with idontification of talents”. From the three dimensions of feature description, aggregation based on association and evaluation, a general expert indicator system was constructed in the scientific&research field, and expounded the calculation method of each indicator in detail. Then an intelligent information service platform of scientific research evaluation was constructed based on the evaluation system, which achieved a variety of academic databases information collection, collation, analysis and mining automation. By automatically filter specified domain experts, intelligently identify their field of study, so as to construct domain expert database system. Especially the implementation of the depth of aggregation of domain experts resources and visualization based on various association between expert, and can provide information services and decision making support to the scientific researchers and the department of research and development management.

  6. Research on Construction of Domain Expert Database System%领域专家库系统构建研究1)

    Institute of Scientific and Technical Information of China (English)

    杜晖; 邱均平

    2014-01-01

    领域专家库系统的建设是符合我国人才发展战略规划中“建设人才信息网络,评价人才与发现人才相结合”指导思想的重要应用研究。文中从特征描述、科学评价和关联聚合三个维度构建了一个通用的领域专家指标体系,并详细阐述了各指标的计算方法,然后在此基础上通过对学术数据库的信息采集、整理、分析与挖掘的自动化处理,筛选指定领域专家,智能识别其研究领域,从而构建领域专家库系统。特别是基于专家间的各种关联关系实现了对相关领域专家资源的深度聚合与可视化揭示,能够为科研工作者和科研管理部门提供相应的信息服务和决策支持。%Construction of domain expert information systems is an important application research, which that “talent information network should be built so as to combine the evaluation of talents, is in align with the statement in China s strategic plan for talent development, with idontification of talents”. From the three dimensions of feature description, aggregation based on association and evaluation, a general expert indicator system was constructed in the scientific&research field, and expounded the calculation method of each indicator in detail. Then an intelligent information service platform of scientific research evaluation was constructed based on the evaluation system, which achieved a variety of academic databases information collection, collation, analysis and mining automation. By automatically filter specified domain experts, intelligently identify their field of study, so as to construct domain expert database system. Especially the implementation of the depth of aggregation of domain experts resources and visualization based on various association between expert, and can provide information services and decision making support to the scientific researchers and the department of research and development management.

  7. Stackfile Database

    Science.gov (United States)

    deVarvalho, Robert; Desai, Shailen D.; Haines, Bruce J.; Kruizinga, Gerhard L.; Gilmer, Christopher

    2013-01-01

    This software provides storage retrieval and analysis functionality for managing satellite altimetry data. It improves the efficiency and analysis capabilities of existing database software with improved flexibility and documentation. It offers flexibility in the type of data that can be stored. There is efficient retrieval either across the spatial domain or the time domain. Built-in analysis tools are provided for frequently performed altimetry tasks. This software package is used for storing and manipulating satellite measurement data. It was developed with a focus on handling the requirements of repeat-track altimetry missions such as Topex and Jason. It was, however, designed to work with a wide variety of satellite measurement data [e.g., Gravity Recovery And Climate Experiment -- GRACE). The software consists of several command-line tools for importing, retrieving, and analyzing satellite measurement data.

  8. Fiscal 1996 report on the investigational research on the construction of a database of physical functions; 1996 nendo chosa hokokusho (shintai kino database no kochiku ni kansuru chosa kenkyu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    For the purpose of realizing `the affluence` sought in the Japanese economic society, the supply and preparation of products, service and environments friendly to human beings seem to be important. In the future, the development of products which are fully considered also of aged and handicapped people is more expected than the conventional manufacturing of products added with value. Especially in accordance with the rapid aging, from a viewpoint that the lowering of physical functions caused by aging has an exactly close relation with the response to products and the environment, development of the database of physical functions for the aged which is useful for the design is urgently promoted. First, the data to be supplied for database were selected. As to the selection method, the data required for database were defined by collection/analysis of the existing data, examination of the needs of enterprise designers, and analysis of daily activities. In the study of the database, the structure by which data can be effectively supplied was studied and verified by pilot database for extraction of the subjects and solution to the problems. 6 refs., 57 figs., 26 tabs.

  9. Tidal Creek Sentinel Habitat Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Ecological Research, Assessment and Prediction's Tidal Creeks: Sentinel Habitat Database was developed to support the National Oceanic and Atmospheric...

  10. DATABASE REPLICATION IN HETEROGENOUS PLATFORM

    Directory of Open Access Journals (Sweden)

    Hendro Nindito

    2014-01-01

    Full Text Available The application of diverse database technologies in enterprises today is increasingly a common practice. To provide high availability and survavibality of real-time information, a database replication technology that has capability to replicate databases under heterogenous platforms is required. The purpose of this research is to find the technology with such capability. In this research, the data source is stored in MSSQL database server running on Windows. The data will be replicated to MySQL running on Linux as the destination. The method applied in this research is prototyping in which the processes of development and testing can be done interactively and repeatedly. The key result of this research is that the replication technology applied, which is called Oracle GoldenGate, can successfully manage to do its task in replicating data in real-time and heterogeneous platforms.

  11. The Neotoma Paleoecology Database

    Science.gov (United States)

    Grimm, E. C.; Ashworth, A. C.; Barnosky, A. D.; Betancourt, J. L.; Bills, B.; Booth, R.; Blois, J.; Charles, D. F.; Graham, R. W.; Goring, S. J.; Hausmann, S.; Smith, A. J.; Williams, J. W.; Buckland, P.

    2015-12-01

    The Neotoma Paleoecology Database (www.neotomadb.org) is a multiproxy, open-access, relational database that includes fossil data for the past 5 million years (the late Neogene and Quaternary Periods). Modern distributional data for various organisms are also being made available for calibration and paleoecological analyses. The project is a collaborative effort among individuals from more than 20 institutions worldwide, including domain scientists representing a spectrum of Pliocene-Quaternary fossil data types, as well as experts in information technology. Working groups are active for diatoms, insects, ostracodes, pollen and plant macroscopic remains, testate amoebae, rodent middens, vertebrates, age models, geochemistry and taphonomy. Groups are also active in developing online tools for data analyses and for developing modules for teaching at different levels. A key design concept of NeotomaDB is that stewards for various data types are able to remotely upload and manage data. Cooperatives for different kinds of paleo data, or from different regions, can appoint their own stewards. Over the past year, much progress has been made on development of the steward software-interface that will enable this capability. The steward interface uses web services that provide access to the database. More generally, these web services enable remote programmatic access to the database, which both desktop and web applications can use and which provide real-time access to the most current data. Use of these services can alleviate the need to download the entire database, which can be out-of-date as soon as new data are entered. In general, the Neotoma web services deliver data either from an entire table or from the results of a view. Upon request, new web services can be quickly generated. Future developments will likely expand the spatial and temporal dimensions of the database. NeotomaDB is open to receiving new datasets and stewards from the global Quaternary community

  12. ASIAN AGRICULTURAL RESEARCH is indexed by CABI,CSA Illumina,AGE and other famous databases,famous research institutes and teaching organizations of many countries

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>Through the joint efforts of personnel in editorial office and multitudinous readers, ASIAN AGRICULTURAL RESEARCH eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as

  13. ASIAN AGRICULTURAL RESEARCH is indexed by CABI,CSA Illumina,AGE and other famous databases,famous research institutes and teaching organizations of many countries

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>Through the joint efforts of personnel in editorial office and multitudinous readers, ASIAN AGRICULTURAL RESEARCH eventually passes the extremely strid appraisal, to be indexed by CABI’s full text repository.

  14. Animal QTLdb:an improved database tool for livestock animal QTL/association data dissemination in the post-genome era

    OpenAIRE

    Hu, Zhi-Liang; Park, Carissa A.; Wu, Xiao-Lin; Reecy, James M.

    2013-01-01

    The Animal QTL database (QTLdb; http://www.animalgenome.org/QTLdb) is designed to house all publicly available QTL and single-nucleotide polymorphism/gene association data on livestock animal species. An earlier version was published in the Nucleic Acids Research Database issue in 2007. Since then, we have continued our efforts to develop new and improved database tools to allow more data types, parameters and functions. Our efforts have transformed the Animal QTLdb into a tool that actively ...

  15. The new database “Seed oil Fatty Acids” (SOFA)

    OpenAIRE

    Matthäus, B.; Aitzetmüller, K.; Friedrich, H. (Hergen)

    2003-01-01

    More than 30 years i n formation about the fatty acid composit ion of wi ld plant seeds was collected f rom the appropriate pharmaceutical, botanical and chemical literature by the former Institute for Chemistry and Physics of Lipids of the Federal Center for Cereal, Potato and Lipid Research in Münster. Since it was very difficult to search this unique source of information, the collection was transferred into an electronically searchable database. This plan was supported by financial assist...

  16. Research of cache technology in wide area sensor database%广域传感器数据库中的缓存技术研究

    Institute of Scientific and Technical Information of China (English)

    庄绪路

    2015-01-01

    广域传感器数据库是当前国际上备受关注的由多学科高度交叉的新兴热点研究领域。广域传感器数据库具有巨大的应用价值,应用前景十分广阔。基于缓存技术和预取技术,提出了一种缓存技术与预取技术相结合的体系结构。对体系结构中各个模块的功能和实现算法进行了详细阐述,对算法进行了复杂性和实例分析,有效地解决了广域传感器数据库系统中,低频结点数据进入缓存替换出高频结点数据所造成的缓存命中率低和系统资源浪费问题。%Wide area sensor database is the current international concerns and the interdisciplinary emerging hot research field, it has very broad application prospect and great application value. Based on combination of the caching with prefetching technology, a system structure is put forward, the function and the algorithm of each module in the system structure is set forth,and the complexity of the algorithm is analysed with the example. The problem of low hit ratio and the waste of system resources in wide area sensor database, that is caused by the high frequency node data be replaced when the low frequency node data get into the cache, is effectively solved.

  17. The Definition of a Prolonged Intensive Care Unit Stay for Spontaneous Intracerebral Hemorrhage Patients: An Application with National Health Insurance Research Database

    Directory of Open Access Journals (Sweden)

    Chien-Lung Chan

    2014-01-01

    Full Text Available Introduction. Length of stay (LOS in the intensive care unit (ICU of spontaneous intracerebral hemorrhage (sICH patients is one of the most important issues. The disease severity, psychosocial factors, and institutional factors will influence the length of ICU stay. This study is used in the Taiwan National Health Insurance Research Database (NHIRD to define the threshold of a prolonged ICU stay in sICH patients. Methods. This research collected the demographic data of sICH patients in the NHIRD from 2005 to 2009. The threshold of prolonged ICU stay was calculated using change point analysis. Results. There were 1599 sICH patients included. A prolonged ICU stay was defined as being equal to or longer than 10 days. There were 436 prolonged ICU stay cases and 1163 nonprolonged cases. Conclusion. This study showed that the threshold of a prolonged ICU stay is a good indicator of hospital utilization in ICH patients. Different hospitals have their own different care strategies that can be identified with a prolonged ICU stay. This indicator can be improved using quality control methods such as complications prevention and efficiency of ICU bed management. Patients’ stay in ICUs and in hospitals will be shorter if integrated care systems are established.

  18. Database on wind characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, K.S. [The Technical Univ. of Denmark (Denmark); Courtney, M.S. [Risoe National Lab., (Denmark)

    1999-08-01

    The organisations that participated in the project consists of five research organisations: MIUU (Sweden), ECN (The Netherlands), CRES (Greece), DTU (Denmark), Risoe (Denmark) and one wind turbine manufacturer: Vestas Wind System A/S (Denmark). The overall goal was to build a database consisting of a large number of wind speed time series and create tools for efficiently searching through the data to select interesting data. The project resulted in a database located at DTU, Denmark with online access through the Internet. The database contains more than 50.000 hours of measured wind speed measurements. A wide range of wind climates and terrain types are represented with significant amounts of time series. Data have been chosen selectively with a deliberate over-representation of high wind and complex terrain cases. This makes the database ideal for wind turbine design needs but completely unsuitable for resource studies. Diversity has also been an important aim and this is realised with data from a large range of terrain types; everything from offshore to mountain, from Norway to Greece. (EHS)

  19. DMPD: The role of viral nucleic acid recognition in dendritic cells for innate andadaptive antiviral immunity. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 18086372 The role of viral nucleic acid recognition in dendritic cells for innate andadaptive...ritic cells for innate andadaptive antiviral immunity. PubmedID 18086372 Title Th...e role of viral nucleic acid recognition in dendritic cells for innate andadaptive antiviral immunity. Autho

  20. ASIAN AGRICULTURAL RESEARCH is indexed by CABI,CSA Illumina,AGE and other famous databases,famous research institutes and teaching organizations of many countries

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>Through the joint efforts of personnel in editorial office and multitudinous readers, ASIAN AGRICULTURAL RESEARCH eventually passes the extremely strict appraisal, to be indexed by CABI’s full text repository. CABI is globally acclaimed as one of the most authoritative and

  1. Database development and management

    CERN Document Server

    Chao, Lee

    2006-01-01

    Introduction to Database Systems Functions of a DatabaseDatabase Management SystemDatabase ComponentsDatabase Development ProcessConceptual Design and Data Modeling Introduction to Database Design Process Understanding Business ProcessEntity-Relationship Data Model Representing Business Process with Entity-RelationshipModelTable Structure and NormalizationIntroduction to TablesTable NormalizationTransforming Data Models to Relational Databases .DBMS Selection Transforming Data Models to Relational DatabasesEnforcing ConstraintsCreating Database for Business ProcessPhysical Design and Database

  2. Towards P2P XML Database Technology

    NARCIS (Netherlands)

    Zhang, Y.

    2007-01-01

    To ease the development of data-intensive P2P applications, we envision a P2P XML Database Management System (P2P XDBMS) that acts as a database middle-ware, providing a uniform database abstraction on top of a dynamic set of distributed data sources. In this PhD work, we research which features suc

  3. Information Literacy Skills: Comparing and Evaluating Databases

    Science.gov (United States)

    Grismore, Brian A.

    2012-01-01

    The purpose of this database comparison is to express the importance of teaching information literacy skills and to apply those skills to commonly used Internet-based research tools. This paper includes a comparison and evaluation of three databases (ProQuest, ERIC, and Google Scholar). It includes strengths and weaknesses of each database based…

  4. Data Extraction and Management in Networks of Observational Health Care Databases for Scientific Research: A Comparison of EU-ADR, OMOP, Mini-Sentinel and MATRICE Strategies

    Science.gov (United States)

    Gini, Rosa; Schuemie, Martijn; Brown, Jeffrey; Ryan, Patrick; Vacchi, Edoardo; Coppola, Massimo; Cazzola, Walter; Coloma, Preciosa; Berni, Roberto; Diallo, Gayo; Oliveira, José Luis; Avillach, Paul; Trifirò, Gianluca; Rijnbeek, Peter; Bellentani, Mariadonata; van Der Lei, Johan; Klazinga, Niek; Sturkenboom, Miriam

    2016-01-01

    Introduction: We see increased use of existing observational data in order to achieve fast and transparent production of empirical evidence in health care research. Multiple databases are often used to increase power, to assess rare exposures or outcomes, or to study diverse populations. For privacy and sociological reasons, original data on individual subjects can’t be shared, requiring a distributed network approach where data processing is performed prior to data sharing. Case Descriptions and Variation Among Sites: We created a conceptual framework distinguishing three steps in local data processing: (1) data reorganization into a data structure common across the network; (2) derivation of study variables not present in original data; and (3) application of study design to transform longitudinal data into aggregated data sets for statistical analysis. We applied this framework to four case studies to identify similarities and differences in the United States and Europe: Exploring and Understanding Adverse Drug Reactions by Integrative Mining of Clinical Records and Biomedical Knowledge (EU-ADR), Observational Medical Outcomes Partnership (OMOP), the Food and Drug Administration’s (FDA’s) Mini-Sentinel, and the Italian network—the Integration of Content Management Information on the Territory of Patients with Complex Diseases or with Chronic Conditions (MATRICE). Findings: National networks (OMOP, Mini-Sentinel, MATRICE) all adopted shared procedures for local data reorganization. The multinational EU-ADR network needed locally defined procedures to reorganize its heterogeneous data into a common structure. Derivation of new data elements was centrally defined in all networks but the procedure was not shared in EU-ADR. Application of study design was a common and shared procedure in all the case studies. Computer procedures were embodied in different programming languages, including SAS, R, SQL, Java, and C++. Conclusion: Using our conceptual framework

  5. Unifying Memory and Database Transactions

    Science.gov (United States)

    Dias, Ricardo J.; Lourenço, João M.

    Software Transactional Memory is a concurrency control technique gaining increasing popularity, as it provides high-level concurrency control constructs and eases the development of highly multi-threaded applications. But this easiness comes at the expense of restricting the operations that can be executed within a memory transaction, and operations such as terminal and file I/O are either not allowed or incur in serious performance penalties. Database I/O is another example of operations that usually are not allowed within a memory transaction. This paper proposes to combine memory and database transactions in a single unified model, benefiting from the ACID properties of the database transactions and from the speed of main memory data processing. The new unified model covers, without differentiating, both memory and database operations. Thus, the users are allowed to freely intertwine memory and database accesses within the same transaction, knowing that the memory and database contents will always remain consistent and that the transaction will atomically abort or commit the operations in both memory and database. This approach allows to increase the granularity of the in-memory atomic actions and hence, simplifies the reasoning about them.

  6. Contig sequences and their annotation (amino acid sequence and results of homology search), and expression profile - Dicty_cDB | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available [ Credits ] BLAST Search Image Search Home About Archive Update History Contact us Dicty_cDB Contig sequence...s and their annotation (amino acid sequence and results of homology search), and ex...pression profile Data detail Data name Contig sequences and their annotation (amino acid sequence and result...s of homology search), and expression profile Description of data contents Contig sequences of cDNA sequen...ces of Dictyostelium discoideum and their annotation (amino acid sequence and resul

  7. Database systems for knowledge-based discovery.

    Science.gov (United States)

    Jagarlapudi, Sarma A R P; Kishan, K V Radha

    2009-01-01

    Several database systems have been developed to provide valuable information from the bench chemist to biologist, medical practitioner to pharmaceutical scientist in a structured format. The advent of information technology and computational power enhanced the ability to access large volumes of data in the form of a database where one could do compilation, searching, archiving, analysis, and finally knowledge derivation. Although, data are of variable types the tools used for database creation, searching and retrieval are similar. GVK BIO has been developing databases from publicly available scientific literature in specific areas like medicinal chemistry, clinical research, and mechanism-based toxicity so that the structured databases containing vast data could be used in several areas of research. These databases were classified as reference centric or compound centric depending on the way the database systems were designed. Integration of these databases with knowledge derivation tools would enhance the value of these systems toward better drug design and discovery.

  8. Database systems for knowledge-based discovery.

    Science.gov (United States)

    Jagarlapudi, Sarma A R P; Kishan, K V Radha

    2009-01-01

    Several database systems have been developed to provide valuable information from the bench chemist to biologist, medical practitioner to pharmaceutical scientist in a structured format. The advent of information technology and computational power enhanced the ability to access large volumes of data in the form of a database where one could do compilation, searching, archiving, analysis, and finally knowledge derivation. Although, data are of variable types the tools used for database creation, searching and retrieval are similar. GVK BIO has been developing databases from publicly available scientific literature in specific areas like medicinal chemistry, clinical research, and mechanism-based toxicity so that the structured databases containing vast data could be used in several areas of research. These databases were classified as reference centric or compound centric depending on the way the database systems were designed. Integration of these databases with knowledge derivation tools would enhance the value of these systems toward better drug design and discovery. PMID:19727614

  9. Database Description - KOME | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available KOME Database Description General information of database Database name Knowledge-based Oryza Molecular biological...baraki 305-8602, Japan National Institute of Agrobiological Sciences Plant Genome Research Unit Shoshi Kikuc...ca rice Author name(s): Rice Full-Length cDNA Consortium; National Institute of Agrobiological Sciences Rice...base maintenance site National Institute of Agrobiological Sciences URL of the original website http://cdna0... Encyclopedia Alternative name KOME Creator Creator Name: Shoshi Kikuchi Creator Affiliation: National Institute of Agrobiologi

  10. Data integration for European marine biodiversity research: creating a database on benthos and plankton to study large-scale patterns and long-term changes

    NARCIS (Netherlands)

    Vandepitte, L.; Vanhoorne, B.; Kraberg, A.; Craeymeersch, J.A.M.

    2010-01-01

    The general aim of setting up a central database on benthos and plankton was to integrate long-, medium- and short-term datasets on marine biodiversity. Such a database makes it possible to analyse species assemblages and their changes on spatial and temporal scales across Europe. Data collation las

  11. ARTI Refrigerant Database

    Energy Technology Data Exchange (ETDEWEB)

    Calm, J.M.

    1992-11-09

    The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air- conditioning and refrigeration equipment. The database identifies sources of specific information on R-32, R-123, R-124, R-125, R-134, R-134a, R-141b, R-142b, R-143a, R-152a, R-245ca, R-290 (propane), R- 717 (ammonia), ethers, and others as well as azeotropic and zeotropic and zeotropic blends of these fluids. It addresses lubricants including alkylbenzene, polyalkylene glycol, ester, and other synthetics as well as mineral oils. It also references documents on compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits. A computerized version is available that includes retrieval software.

  12. 数据库加密技术的研究与应用%Research and Application of Database Encryption Technology

    Institute of Scientific and Technical Information of China (English)

    韩利凯

    2011-01-01

    数据库加密技术是实现数据库信息安全的一种有效方法.从数据库系统的安全需求着手,对数据库加密的基本要求、数据库加密技术中的关键问题等进行了研究和探讨,提出了数据库加密技术在B/S学籍管理系统中的实现方案.%Database encryption technology is an effective method for realizing database information security.This article studies and discusses the basic requirements of database encryption and the key problems in database encryption technology.It also puts forward a scheme of applying database encryption technology in B/S registration management system.

  13. 多媒体数据库技术的分析与研究%Analysis and Research on the Multimedia Database Technology

    Institute of Scientific and Technical Information of China (English)

    张莉

    2012-01-01

    The multimedia database is a combination of database and multimedia technique. Introduces multimedia database system and its system structure, according to the inspectional way and index process of contents. Taking the VF database management system as an example to introduce the implementation method of multimedia database.%多媒体数据库是数据库与多媒体技术的结合。介绍多媒体数据库系统及其体系结构,基于内容的检索方式及检索过程,并以VF数据库管理系统为例介绍多媒体数据库的实现方法。

  14. KALIMER design database development and operation manual

    International Nuclear Information System (INIS)

    KALIMER Design Database is developed to utilize the integration management for Liquid Metal Reactor Design Technology Development using Web Applications. KALIMER Design database consists of Results Database, Inter-Office Communication (IOC), 3D CAD database, Team Cooperation System, and Reserved Documents. Results Database is a research results database for mid-term and long-term nuclear R and D. IOC is a linkage control system inter sub project to share and integrate the research results for KALIMER. 3D CAD Database is a schematic design overview for KALIMER. Team Cooperation System is to inform team member of research cooperation and meetings. Finally, KALIMER Reserved Documents is developed to manage collected data and several documents since project accomplishment

  15. Study on Establishment and Research of a National Costumes Database System%民族服饰数据库系统的建立与研究

    Institute of Scientific and Technical Information of China (English)

    郭敏

    2015-01-01

    从民族服饰文化的现状入手,研究了民族服饰数据库系统的总体设计、系统实现的关键技术、主要功能模块的设计,并挖掘出其长远的应用前景. 此系统的建立,弘扬了民族服饰文化,使得民族服饰文化遗产得到了很好的保存.%Starting from the current situation of national costumes culture ,it researched the overall design of national costumes database system ,the key techniques of system implementation ,the design of the main functional modules in this paper ,and dug the system′s long-term application prospect .The establishment of this system which carries forward the national costume culture ,making the national dress culture herit-age is well preserved .

  16. Databases and their application

    NARCIS (Netherlands)

    E.C. Grimm; R.H.W Bradshaw; S. Brewer; S. Flantua; T. Giesecke; A.M. Lézine; H. Takahara; J.W.,Jr Williams

    2013-01-01

    During the past 20 years, several pollen database cooperatives have been established. These databases are now constituent databases of the Neotoma Paleoecology Database, a public domain, multiproxy, relational database designed for Quaternary-Pliocene fossil data and modern surface samples. The poll

  17. Unit 66 - Database Creation

    OpenAIRE

    Unit 61, CC in GIS; National Center for Geographic Information and Analysis (UC Santa Barbara, SUNY at Buffalo, University of Maine)

    1990-01-01

    This unit examines the planning and management issues involved in the physical creation of the database. It describes some issues in database creation, key hardware parameters of the system, partitioning the database for tiles and layers and converting data for the database. It illustrates these through an example from the Flathead National Forest in northwestern Montana, where a resource management database was required.

  18. OECD/NEA thermochemical database

    International Nuclear Information System (INIS)

    This state of the art report is to introduce the contents of the Chemical Data-Service, OECD/NEA, and the results of survey by OECD/NEA for the thermodynamic and kinetic database currently in use. It is also to summarize the results of Thermochemical Database Projects of OECD/NEA. This report will be a guide book for the researchers easily to get the validate thermodynamic and kinetic data of all substances from the available OECD/NEA database. (author). 75 refs

  19. Construction of a Geographical Database of Classical-Archaic Manufactures, Found in the Survey of the Greek Colony Himera (sicily, Italy). Application and Methodologies for AN Experimental Research

    Science.gov (United States)

    Papa, M. A.; Tardo, V.

    2011-09-01

    This research has analysed the distribution of ceramic finds from classical and archaic ages in the territory of the ancient Greek colony Himera, a town situated near Termini Imerese, in the province of Palermo (Sicily, Italy), which has been the site of systematic excavations carried out by the University of Palermo since the Sixties. The study of about 1500 ceramic fragments, dated back to the 6th-5th century B.C., has allowed to develop an approach to the understanding of the role played by ceramics in the relations between different societies and cultures. Besides the most common analysis factors for the ceramic manufactures, such as their production and distribution, a major factor is the way the manufactures were used. From this wider perspective, a new methodology has been developed about information potential of functional analysis. The interpretation of data about the manufacture distribution was made by means of GIS methodologies, querying the alphanumerical classification database and relating the manufacture typological data to the geo-cartographic ones by means of applying intersite-level spatial analysis. Thus, each archaeological piece of information about the finds can be analysed in relation to the territory geo-morphological features and the obtained data can be processed with specific software environments, in order to suggest reconstruction models for the anthropic landscape, based on the relation between coeval sites and distance from specific environment features — for example, distance from water sources, raw materials, road condition etc. The computer application used for data handling, presentation and analysis, becomes this way a tool of research aimed at the comprehension of settlement dynamics in the historical scenery. This study is the occasion to propose such an analysis system of cultural heritage as a new tool to promote it and to increase its value, applying a territorial context related methodology founded on scientific evidence.

  20. Small Business Innovations (Integrated Database)

    Science.gov (United States)

    1992-01-01

    Because of the diversity of NASA's information systems, it was necessary to develop DAVID as a central database management system. Under a Small Business Innovation Research (SBIR) grant, Ken Wanderman and Associates, Inc. designed software tools enabling scientists to interface with DAVID and commercial database management systems, as well as artificial intelligence programs. The software has been installed at a number of data centers and is commercially available.

  1. Charged particle cross-section database for medical radioisotope production: diagnostic radioisotopes and monitor reactions. Final report of a co-ordinated research project

    International Nuclear Information System (INIS)

    Medical applications of nuclear radiation are of considerable interest to the IAEA. Cyclotrons and accelerators, available in recent years in an increasing number of countries, are being used for the production of radioisotopes for both diagnostic and therapeutic purposes. The physical basis of this production is described through interaction of charged particles, such as protons, deuterons and alphas, with matter. These processes have to be well understood in order to produce radioisotopes in an efficient and clean manner. In addition to medical radioisotope production, reactions with low energy charged particles are of primary importance for two major applications. Techniques of ion beam analysis use many specific reactions to identify material properties, and in nuclear astrophysics there is interest in numerous reaction rates to understand nucleosynthesis in the Universe. A large number of medically oriented cyclotrons have been running in North America, western Europe and Japan for more than two decades. In recent years, 30-40 MeV cyclotrons and smaller cyclotrons (Ep < 20 MeV) have been installed in several countries. Although the production methods are well established, there are no evaluated and recommended nuclear data sets available. The need for standardization was thus imminent. This was pointed out at three IAEA meetings. Based on the recommendations made at these meetings, the IAEA decided to undertake and organize the Co-ordinated Research Project (CRP) on Development of Reference Charged Particle Cross-Section Database for Medical Radioisotope Production. The project was initiated in 1995. It focused on radioisotopes for diagnostic purposes and on the related beam monitor reactions in order to meet current needs. It constituted the first major international effort dedicated to standardization of nuclear data for radioisotope production. It covered the following areas: Compilation of data on the most important reactions for monitoring light ion

  2. World Religion Database

    OpenAIRE

    Dekker, Jennifer

    2009-01-01

    This article reviews the new database released by Brill entitled World Religion Database (WRD). It compares WRD to other religious demography tools available and rates the database on a 5 point scale.

  3. Oracle数据库启动过程研究与实践%Research and Operation of Oracle database startup process

    Institute of Scientific and Technical Information of China (English)

    周文琼; 王乐球

    2011-01-01

    On the basis of the analysis Oracle database startup process,described Oracle database startup failure led to different reasons,to simulate a variety of fault,the fault handling process,so that readers better understanding Oracle database startup process.%分析了Oracle数据库启动过程,阐述了导致Oracle数据库启动故障的不同原因,模拟了各种故障,提出了故障的处理过程,使读者对Oracle数据库启动过程有更深入的了解。

  4. International Ventilation Cooling Application Database

    DEFF Research Database (Denmark)

    Holzer, Peter; Psomas, Theofanis Ch.; OSullivan, Paul

    2016-01-01

    The currently running International Energy Agency, Energy and Conservation in Buildings, Annex 62 Ventilative Cooling (VC) project, is coordinating research towards extended use of VC. Within this Annex 62 the joint research activity of International VC Application Database has been carried out, ...

  5. Open geochemical database

    Science.gov (United States)

    Zhilin, Denis; Ilyin, Vladimir; Bashev, Anton

    2010-05-01

    We regard "geochemical data" as data on chemical parameters of the environment, linked with the geographical position of the corresponding point. Boosting development of global positioning system (GPS) and measuring instruments allows fast collecting of huge amounts of geochemical data. Presently they are published in scientific journals in text format, that hampers searching for information about particular places and meta-analysis of the data, collected by different researchers. Part of the information is never published. To make the data available and easy to find, it seems reasonable to elaborate an open database of geochemical information, accessible via Internet. It also seems reasonable to link the data with maps or space images, for example, from GoogleEarth service. For this purpose an open geochemical database is being elaborating (http://maps.sch192.ru). Any user after registration can upload geochemical data (position, type of parameter and value of the parameter) and edit them. Every user (including unregistered) can (a) extract the values of parameters, fulfilling desired conditions and (b) see the points, linked to GoogleEarth space image, colored according to a value of selected parameter. Then he can treat extracted values any way he likes. There are the following data types in the database: authors, points, seasons and parameters. Author is a person, who publishes the data. Every author can declare his own profile. A point is characterized by its geographical position and type of the object (i.e. river, lake etc). Value of parameters are linked to a point, an author and a season, when they were obtained. A user can choose a parameter to place on GoogleEarth space image and a scale to color the points on the image according to the value of a parameter. Currently (December, 2009) the database is under construction, but several functions (uploading data on pH and electrical conductivity and placing colored points onto GoogleEarth space image) are

  6. Hydrogen-bond landscapes, geometry and energetics of squaric acid and its mono- and dianions: a Cambridge Structural Database, IsoStar and computational study

    NARCIS (Netherlands)

    F.H. Allen; A.J. Cruz-Cabeza; P.A. Wood; D.A. Bardwell

    2013-01-01

    As part of a programme of work to extend central-group coverage in the Cambridge Crystallographic Data Centre's (CCDC) IsoStar knowledge base of intermolecular interactions, we have studied the hydrogen-bonding abilities of squaric acid (H(2)SQ) and its mono-and dianions (HSQ(-) and SQ(2-)) using th

  7. Human cancer databases (review).

    Science.gov (United States)

    Pavlopoulou, Athanasia; Spandidos, Demetrios A; Michalopoulos, Ioannis

    2015-01-01

    Cancer is one of the four major non‑communicable diseases (NCD), responsible for ~14.6% of all human deaths. Currently, there are >100 different known types of cancer and >500 genes involved in cancer. Ongoing research efforts have been focused on cancer etiology and therapy. As a result, there is an exponential growth of cancer‑associated data from diverse resources, such as scientific publications, genome‑wide association studies, gene expression experiments, gene‑gene or protein‑protein interaction data, enzymatic assays, epigenomics, immunomics and cytogenetics, stored in relevant repositories. These data are complex and heterogeneous, ranging from unprocessed, unstructured data in the form of raw sequences and polymorphisms to well‑annotated, structured data. Consequently, the storage, mining, retrieval and analysis of these data in an efficient and meaningful manner pose a major challenge to biomedical investigators. In the current review, we present the central, publicly accessible databases that contain data pertinent to cancer, the resources available for delivering and analyzing information from these databases, as well as databases dedicated to specific types of cancer. Examples for this wealth of cancer‑related information and bioinformatic tools have also been provided. PMID:25369839

  8. ARTI Refrigerant Database

    Energy Technology Data Exchange (ETDEWEB)

    Cain, J.M. [Calm (James M.), Great Falls, VA (United States)

    1993-04-30

    The Refrigerant Database consolidates and facilitates access to information to assist industry in developing equipment using alternative refrigerants. The underlying purpose is to accelerate phase out of chemical compounds of environmental concern. The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air-conditioning and refrigeration equipment. The complete documents are not included. The database identifies sources of specific information on R-32, R-123, R-124, R-125, R-134, R-134a, R-141b, R-142b, R-143a, R-152a, R-245ca, R-290 (propane), R-717 (ammonia), ethers, and others as well as azeotropic and zeotropic blends of these fluids. It addresses lubricants including alkylbenzene, polyalkylene glycol, ester, and other synthetics as well as mineral oils. It also references documents addressing compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits. Incomplete citations or abstracts are provided for some documents to accelerate availability of the information and will be completed or replaced in future updates.

  9. ARTI refrigerant database

    Energy Technology Data Exchange (ETDEWEB)

    Calm, J.M. [Calm (James M.), Great Falls, VA (United States)

    1998-08-01

    The Refrigerant Database is an information system on alternative refrigerants, associated lubricants, and their use in air conditioning and refrigeration. It consolidates and facilitates access to property, compatibility, environmental, safety, application and other information. It provides corresponding information on older refrigerants, to assist manufactures and those using alternative refrigerants, to make comparisons and determine differences. The underlying purpose is to accelerate phase out of chemical compounds of environmental concern. The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air-conditioning and refrigeration equipment. The complete documents are not included, though some may be added at a later date. The database identifies sources of specific information on many refrigerants including propane, ammonia, water, carbon dioxide, propylene, ethers, and others as well as azeotropic and zeotropic blends of these fluids. It addresses lubricants including alkylbenzene, polyalkylene glycol, polyolester, and other synthetics as well as mineral oils. It also references documents addressing compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits. Incomplete citations or abstracts are provided for some documents. They are included to accelerate availability of the information and will be completed or replaced in future updates.

  10. ARTI refrigerant database

    Energy Technology Data Exchange (ETDEWEB)

    Calm, J.M.

    1997-02-01

    The Refrigerant Database is an information system on alternative refrigerants, associated lubricants, and their use in air conditioning and refrigeration. It consolidates and facilitates access to property, compatibility, environmental, safety, application and other information. It provides corresponding information on older refrigerants, to assist manufacturers and those using alterative refrigerants, to make comparisons and determine differences. The underlying purpose is to accelerate phase out of chemical compounds of environmental concern. The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air-conditioning and refrigeration equipment. The complete documents are not included, though some may be added at a later date. The database identifies sources of specific information on various refrigerants. It addresses lubricants including alkylbenzene, polyalkylene glycol, polyolester, and other synthetics as well as mineral oils. It also references documents addressing compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits. Incomplete citations or abstracts are provided for some documents. They are included to accelerate availability of the information and will be completed or replaced in future updates.

  11. Collecting Taxes Database

    Data.gov (United States)

    US Agency for International Development — The Collecting Taxes Database contains performance and structural indicators about national tax systems. The database contains quantitative revenue performance...

  12. USAID Anticorruption Projects Database

    Data.gov (United States)

    US Agency for International Development — The Anticorruption Projects Database (Database) includes information about USAID projects with anticorruption interventions implemented worldwide between 2007 and...

  13. ADO.NET数据访问体系结构研究%Architecture Research of Database Accessing on ADO.NET

    Institute of Scientific and Technical Information of China (English)

    詹发荣

    2009-01-01

    ADO.NET是基于.NET Framework平台下的数据访问技术.该文介绍了ADO.NET的数据访问工作机理,并对ADO.NET和ADO进行了简单比较,分析了ADO.NET框架下访问数据库的两类核心组件,最后给出了采用ADO.NET访问不同数据库需要引入相应的命名空间.%ADO.NET is a technology of database accessing based on .NET Framework, it introduces ADO.NET's database accessing prin-ciple, and it compares ADO.NET and ADO, Analyzing two core module of accessing database under ADO.NET Framework, Finally, ac-cess to different databases using ADO.NET a need to introduce the corresponding namespace.

  14. Research and Design on the Disk Manager of Spatial Database%空间数据库磁盘管理器的研究与设计

    Institute of Scientific and Technical Information of China (English)

    范建伟; 汪林林

    2003-01-01

    The disk manager of spatial database provides uniform storage and management for spatial data and attribute data in GIS applications. To investigate it will have effect on creating storage manager of spatial database and SDBMS with lore's property right for our country. This paper investigates and analyzes the Oracele's spatial data model, and on the basis of it , it puts forward a new method about disk storage of spatial data and has it designed.

  15. Usability in Scientific Databases

    Directory of Open Access Journals (Sweden)

    Ana-Maria Suduc

    2012-07-01

    Full Text Available Usability, most often defined as the ease of use and acceptability of a system, affects the users' performance and their job satisfaction when working with a machine. Therefore, usability is a very important aspect which must be considered in the process of a system development. The paper presents several numerical data related to the history of the scientific research of the usability of information systems, as it is viewed in the information provided by three important scientific databases, Science Direct, ACM Digital Library and IEEE Xplore Digital Library, at different queries related to this field.

  16. Oracle Database Optimization Strategy Research on Windows Platform%基于windows平台的oracle数据库优化策略研究

    Institute of Scientific and Technical Information of China (English)

    刘峰

    2011-01-01

    甲骨文公司开发的ORACLE数据库是一款关系数据库管理系统,在数据库市场上占有主要份额,其应用十分广泛。本文以数据库性能优化为出发点,基于WINDOWS平台,从系统、网络、数据库等方面,对ORACLE数据库的优化进行了探讨,提出了有效的优化策略。%Oracle ORACLE database development is a relational database management system,the database holds a major share of the market,it is widely used.In this paper, database performance optimization as a starting point,based on the WINDOWS platform, from the system,network,database,etc.,on the ORACLE database optimization are discussed and put forward an effective optimization strategy.

  17. Risk of Mortality (Including Sudden Cardiac Death and Major Cardiovascular Events in Atypical and Typical Antipsychotic Users: A Study with the General Practice Research Database

    Directory of Open Access Journals (Sweden)

    Tarita Murray-Thomas

    2013-01-01

    Full Text Available Objective. Antipsychotics have been associated with increased cardiac events including mortality. This study assessed cardiac events including mortality among antipsychotic users relative to nonusers. Methods. The General Practice Research Database (GPRD was used to identify antipsychotic users, matched general population controls, and psychiatric diseased nonusers. Outcomes included cardiac mortality, sudden cardiac death (SCD, all-cause mortality (excluding suicide, coronary heart disease (CHD, and ventricular arrhythmias (VA. Sensitivity analyses were conducted for age, dose, duration, antipsychotic type, and psychiatric disease. Results. 183,392 antipsychotic users (115,491 typical and 67,901 atypical, 544,726 general population controls, and 193,920 psychiatric nonusers were identified. Nonusers with schizophrenia, dementia, or bipolar disorder had increased risks of all-cause mortality compared to general population controls, while nonusers with major depression had comparable risks. Relative to psychiatric nonusers, the adjusted relative ratios (aRR of all-cause mortality in antipsychotic users was 1.75 (95% CI: 1.64–1.87; cardiac mortality 1.72 (95% CI: 1.42–2.07; SCD primary definition 5.76 (95% CI: 2.90–11.45; SCD secondary definition 2.15 (95% CI: 1.64–2.81; CHD 1.16 (95% CI: 0.94–1.44; and VA 1.16 (95% CI: 1.02–1.31. aRRs of the various outcomes were lower for atypical versus typical antipsychotics (all-cause mortality 0.83 (95% CI: 0.80–0.85; cardiac mortality 0.89 (95% CI: 0.82–0.97; and SCD secondary definition 0.76 (95% CI: 0.55–1.04. Conclusions. Antipsychotic users had an increased risk of cardiac mortality, all-cause mortality, and SCD compared to a psychiatric nonuser cohort.

  18. Research on the Construction of Tissue Engineering Scaffolds by Alginate-hyaluronic Acid with Different Characteristics

    Institute of Scientific and Technical Information of China (English)

    LI Qin-hua; LIU Li; LIN Dong-qing

    2014-01-01

    This research uses alginate and hyaluronic acid as the main component to prepare support, then explores the possibilities as a tissue engineering scaffold. Firstly, prepare HA with various average molecular weight and alginate with different viscosity, mix them up at a certain proportion and make it into a AlgCa 2+-HA composite scaffold with a film-forming method. This article discusses the feasibility of this scaffold used in tissue engineering field according to the consequence of moisture content testing, mechanical analysis, and scanning electron microscopy analysis. The structure and properties of AlgCa2+-HA composite scaffold are closely related to some factors such as average molecular weight of hyaluronic acid, hyaluronic acid concentration, alginate viscosity, cross-linking agents and processing technology. The AlgCa 2+-HA composite material, which is at different proportions and adding different cross-linking agent,has some certain characteristics:moisture content ranging from 50%to 95%, tensile strength between 2.69 N/mm2 and 4.299 N/mm2, and elongation at break is about 58%to 160%. The prepared AlgCa2+-HA composite scaffolds can be used as tissue engineering scaffolds resulting from its high moisture content, good mechanical properties and ideal pore structure.

  19. Research of nickel’s electrochemical property in sulfuric acid solution by using potentiodynamic polarization curve.

    Directory of Open Access Journals (Sweden)

    Bekenova Gulmira

    2015-03-01

    Full Text Available In the presented work in order to deeply study the mechanism of electrode processes that take place while polarizing the nickel electrode in acid solutions by alternating current, potentiodynamic polarization curves were obtained.The detailed study of shapes of polarization curves; their dependence on concentration, temperature, and other physical and chemical parameters, gives opportunity to obtain full information on the nature and kinesthetic of processes taking place on electrode surface. The electrochemical properties of nickel electrode were researched by estimating cyclic potentiodynamic polarization curves in sulfuric acid medium; and the influence of electrolyte concentration, potential giving speed, the temperature of solution on anodic and cathode processes were also studied. The meanings of transfer number (an and diffusion (D coefficient, the reaction order of metal ions during the process of nickel electrode’s anode corrosion in sulfuric acid solution, and the activation energy is estimated. Result of the calculations showed that nickel’s melting process goes in mixed, diffusion-kinetic regime. It was found that the raising of solution’s temperature increases the height of corrosion current. The results of the experiments done during the application of cyclic polarization curves showed that the electrochemical processes that take place in polarization by industrial alternating current in anode and cathode half periods is different from those done in stable current and with more complex mechanism.

  20. Acid rain research program. Annual progress report, September 1975--June 1976

    Energy Technology Data Exchange (ETDEWEB)

    Evans, L.S.; Raynor, G.S.

    1976-09-01

    The aims of the research program are: (a) to observe the minimum threshold dose of simulated acid rain to produce visual and histological effects on plant foliage, (b) approach threshold limits of simulated sulfate acid rain that affect plant growth and reproduction, and (c) to measure chemical and meteorological parameters of incident rain. Acute leaf injury to several plant species resulted from exposure of foliage to simulated sulfate acid rain of pH level 2.3 to 2.9. Only slight injury occurred at 3.1. Scanning electron micrographs showed that injury to upper leaf surfaces occurred mostly at the base of trichomes (leaf hairs) and near stomata. An association of lesion development near vascular tissue was also noted. Histologically, lesions are characterized by an initial collapse of the epidermis with eventual lysis and collapse of more internal leaf tissues on the upper leaf surface of pinto beans which complemented detailed descriptions of visual lesion development after daily exposures to simulated rain. Initial experiments with gametophytes of Pteridium aquilinum show that reproduction of this fern species is very sensitive to solutions of pH 5.2 while vegetative development is not affected at pH levels of 2.2. Initial rain samples from the sequential sampler have been obtained. Initial portions of rain events exhibit a pH near 3.0 in some cases. More complete chemical analyses are anticipated.

  1. License - DMPD | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available distributing any derivative work based on part of whole of the data from this database. 2. When you conduct research... by using this database, and describe the research results in an article

  2. 基于Delhpi平台的数据库程序设计研究%Research on the Database Programming Based on Delphi Platform

    Institute of Scientific and Technical Information of China (English)

    鲍海燕

    2011-01-01

    数据库技术是当今信息社会的重要基础技术之一,在众多的数据库开发工具当中,Delphi尤为突出,它适应于多种数据库结构,具有高效率的数据库管理系统和最新的数据分析手段并且提供大量的企业组件。介绍了基于Delphi平台的数据库程序设计的原理,各组件功能应用以及数据库的连接方法,通过测试程序对比了各个数据库连接方法的访问时间,得出DBExpress方法优于BDE及ADO,大大提高了Delphi程序设计中数据库存取和访问的效率,总结了Delphi数据库开发的步骤,便于使用者学习和应用。%Database technology is one of the most important fundamental technologies in the information society.Among many of the database development tools,Delphi is particularly prominent.It performs highly efficient database management system and the latest data analysis method and provides a lot of enterprise components,which adapts to a variety of database structures.Database technology introduces the function application of each parts,the database connection method and the principle based on Delphi platform database program design.By comparing the visiting time of each database connection method after testing program,we know that DBExpress method is better than BDE and ADO,which greatly improves the efficiency of the Delphi programming database access and visiting.The steps of the Delphi database development is summarized to facilitate the users' study and application.

  3. FAKE FACE DATABASE AND PREPROCESSING

    Directory of Open Access Journals (Sweden)

    Aruni Singh

    2013-02-01

    Full Text Available Face plays an ethical role in human interaction compared to other biometrics. It is most popular non-intrusive and non-invasive biometrics whose image can easily be snapped without user co-operation. That is why; criminals and imposters always try to tamper their facial identity. Therefore, face tampering detection is one of the most important bottlenecks for security, commercial and industrial orbit. Face tampering detection is one of the most important bottlenecks for security, commercial and industrial orbit. In particular, few researchers have addressed the challenges for the disguise detection but inadequacy is benchmark database in public domain. This paper addresses these problems by preparing of three category of tampered face database within the framework of FRT (Facial Recognition Technology and evaluates the performance of this database on face recognition algorithms. These categories of database are dummy, colour imposed and masked face.

  4. Databases of the marine metagenomics

    KAUST Repository

    Mineta, Katsuhiko

    2015-10-28

    The metagenomic data obtained from marine environments is significantly useful for understanding marine microbial communities. In comparison with the conventional amplicon-based approach of metagenomics, the recent shotgun sequencing-based approach has become a powerful tool that provides an efficient way of grasping a diversity of the entire microbial community at a sampling point in the sea. However, this approach accelerates accumulation of the metagenome data as well as increase of data complexity. Moreover, when metagenomic approach is used for monitoring a time change of marine environments at multiple locations of the seawater, accumulation of metagenomics data will become tremendous with an enormous speed. Because this kind of situation has started becoming of reality at many marine research institutions and stations all over the world, it looks obvious that the data management and analysis will be confronted by the so-called Big Data issues such as how the database can be constructed in an efficient way and how useful knowledge should be extracted from a vast amount of the data. In this review, we summarize the outline of all the major databases of marine metagenome that are currently publically available, noting that database exclusively on marine metagenome is none but the number of metagenome databases including marine metagenome data are six, unexpectedly still small. We also extend our explanation to the databases, as reference database we call, that will be useful for constructing a marine metagenome database as well as complementing important information with the database. Then, we would point out a number of challenges to be conquered in constructing the marine metagenome database.

  5. Databases of the marine metagenomics.

    Science.gov (United States)

    Mineta, Katsuhiko; Gojobori, Takashi

    2016-02-01

    The metagenomic data obtained from marine environments is significantly useful for understanding marine microbial communities. In comparison with the conventional amplicon-based approach of metagenomics, the recent shotgun sequencing-based approach has become a powerful tool that provides an efficient way of grasping a diversity of the entire microbial community at a sampling point in the sea. However, this approach accelerates accumulation of the metagenome data as well as increase of data complexity. Moreover, when metagenomic approach is used for monitoring a time change of marine environments at multiple locations of the seawater, accumulation of metagenomics data will become tremendous with an enormous speed. Because this kind of situation has started becoming of reality at many marine research institutions and stations all over the world, it looks obvious that the data management and analysis will be confronted by the so-called Big Data issues such as how the database can be constructed in an efficient way and how useful knowledge should be extracted from a vast amount of the data. In this review, we summarize the outline of all the major databases of marine metagenome that are currently publically available, noting that database exclusively on marine metagenome is none but the number of metagenome databases including marine metagenome data are six, unexpectedly still small. We also extend our explanation to the databases, as reference database we call, that will be useful for constructing a marine metagenome database as well as complementing important information with the database. Then, we would point out a number of challenges to be conquered in constructing the marine metagenome database.

  6. The H-Index of `An Approach to Correlate Tandem Mass Spectral Data of Peptides with Amino Acid Sequences in a Protein Database'

    Science.gov (United States)

    Washburn, Michael P.

    2015-11-01

    Over 20 years ago a remarkable paper was published in the Journal of American Society for Mass Spectrometry. This paper from Jimmy Eng, Ashley McCormack, and John Yates described the use of protein databases to drive the interpretation of tandem mass spectra of peptides. This paper now has over 3660 citations and continues to average more than 260 per year over the last decade. This is an amazing scientific achievement. The reason for this is the paper was a cutting edge development at the moment in time when genomes of organisms were being sequenced, protein and peptide mass spectrometry was growing into the field of proteomics, and the power of computing was growing quickly in accordance with Moore's law. This work by the Yates lab grew in importance as genomics, proteomics, and computation all advanced and eventually resulted in the widely used SEQUEST algorithm and platform for the analysis of tandem mass spectrometry data. This commentary provides an analysis of the impact of this paper by analyzing the citations it has generated and the impact of these citing papers.

  7. EPA's catalyst research program: environmental impact of sulfuric acid emissions

    Energy Technology Data Exchange (ETDEWEB)

    Lee, R.E. Jr.; Duffield, F.V.

    1977-01-01

    A sulfuric acid review conference sponsored by EPA's automotive catalyst research program was held recently at Hendersonville, NC, for researchers whose work is funded by EPA. Emissions characterization research indicated that in-use catalyst-equipped vehicles emit low levels of H/sub 2/SO/sub 4/, averaging 2.7 mg/mile for 49-state cars and 15 mg/mile for California cars. Research on measurement methodology for H/sub 2/SO/sub 4/ and other sulfate compounds has led to the development of several promising techniques based on selective volatilization. In-roadway and off-roadway monitoring programs are providing sulfate data which can lead to improved mathematical predictive models. Acute toxicity studies to date indicate that morphological, biochemical, physiological, and pharmacological alterations due to inhaled H/sub 2/SO/sub 4/ alone do not appear to occur at levels less than 1 mg/m/sup 3/. However, striking effects are noted with combinations of H/sub 2/SO/sub 4/ and other pollutants. Participants identified the need for long term chronic H/sub 2/SO/sub 4/ exposure studies.

  8. Research of the methods of association rules in image database%图像数据库关联规则的挖掘方法研究

    Institute of Scientific and Technical Information of China (English)

    王远敏

    2012-01-01

      In multimedia applications,the use of the image database is increasingly widespread. In order to use image database more effectively,many data mining techniques is used in image database.This paper uses FP_tree techniques in data mining to mine the rule in image database and constructs an new image database system.%  在多媒体应用中,图像数据库的使用日趋广泛,为了更有效地使用图像数据库,许多数据挖掘技术被用于图像数据库中。本文使用数据挖掘中的关联规则方法来进一步提高图像数据库的性能,基于此构建了一个图像数据库系统,在这个系统中使用了FP增长算法挖掘图像数据的关联规则。

  9. 基于Web的数据库安全技术研究%The Research of Database Security Technology based on Web

    Institute of Scientific and Technical Information of China (English)

    吴慧丽; 方加娟

    2011-01-01

    With the rapid spread of network,Web technology widely as,whether Governments,schools,enterprises and institutions,have applied to work in the publicity or Web technologies,Web database information,increasing the amount of storage,Web database security has also been a serious challenge.This article introduces the basic principles of database security and database security technology,detailed description of database keys encryption algorithms.%随着网络的迅速普及,Web技术随之得到广泛应用,无论是政府、学校、企事业单位等都应用到Web技术进行宣传或工作,其Web数据库信息的存储量越来越大,Web数据库的安全也受到了严峻的挑战。本文介绍了数据库安全的基本原理和数据库安全的实现技术,详细描述了数据库的子密钥加密算法。

  10. Logical database design principles

    CERN Document Server

    Garmany, John; Clark, Terry

    2005-01-01

    INTRODUCTION TO LOGICAL DATABASE DESIGNUnderstanding a Database Database Architectures Relational Databases Creating the Database System Development Life Cycle (SDLC)Systems Planning: Assessment and Feasibility System Analysis: RequirementsSystem Analysis: Requirements Checklist Models Tracking and Schedules Design Modeling Functional Decomposition DiagramData Flow Diagrams Data Dictionary Logical Structures and Decision Trees System Design: LogicalSYSTEM DESIGN AND IMPLEMENTATION The ER ApproachEntities and Entity Types Attribute Domains AttributesSet-Valued AttributesWeak Entities Constraint

  11. Ageing Management Program Database

    International Nuclear Information System (INIS)

    The aspects of plant ageing management (AM) gained increasing attention over the last ten years. Numerous technical studies have been performed to study the impact of ageing mechanisms on the safe and reliable operation of nuclear power plants. National research activities have been initiated or are in progress to provide the technical basis for decision making processes. The long-term operation of nuclear power plants is influenced by economic considerations, the socio-economic environment including public acceptance, developments in research and the regulatory framework, the availability of technical infrastructure to maintain and service the systems, structures and components as well as qualified personnel. Besides national activities there are a number of international activities in particular under the umbrella of the IAEA, the OECD and the EU. The paper discusses the process, procedure and database developed for Slovenian Nuclear Safety Administration (SNSA) surveillance of ageing process of Nuclear power Plant Krsko.(author)

  12. The SIMBAD astronomical database

    CERN Document Server

    Wenger, M; Egret, D; Dubois, P; Bonnarel, F; Borde, S; Genova, F; Jasniewicz, G; Laloe, S; Lesteven, S; Monier, R; Wenger, Marc; Ochsenbein, Francois; Egret, Daniel; Dubois, Pascal; Bonnarel, Francois; Borde, Suzanne; Genova, Francoise; Jasniewicz, Gerard; Laloe, Suzanne; Lesteven, Soizick; Monier, Richard

    2000-01-01

    Simbad is the reference database for identification and bibliography ofastronomical objects. It contains identifications, `basic data', bibliography,and selected observational measurements for several million astronomicalobjects. Simbad is developed and maintained by CDS, Strasbourg. Building thedatabase contents is achieved with the help of several contributing institutes.Scanning the bibliography is the result of the collaboration of CDS withbibliographers in Observatoire de Paris (DASGAL), Institut d'Astrophysique deParis, and Observatoire de Bordeaux. When selecting catalogues and tables forinclusion, priority is given to optimal multi-wavelength coverage of thedatabase, and to support of research developments linked to large projects. Inparallel, the systematic scanning of the bibliography reflects the diversityand general trends of astronomical research. A WWW interface to Simbad is available at: http://simbad.u-strasbg.fr/Simbad

  13. 核酸疫苗研究进展%Research progress in nucleic acid vaccine

    Institute of Scientific and Technical Information of China (English)

    邵杰; 梁争论

    2014-01-01

    核酸疫苗是将编码某种抗原的外源基因(DNA或RNA)直接导入动物体细胞内,通过宿主细胞表达系统合成抗原,诱导宿主产生对该抗原的免疫应答,以达到防治疾病目的的一类新型疫苗.研究表明,核酸疫苗不仅具有良好的免疫原性和安全性,而且由于核酸更易于修饰和改造,使核酸疫苗较以往蛋白疫苗具有更大的灵活性.在实际生产中,核酸疫苗的制备和纯化工艺较为简单,生产周期短,生产成本低,且易于制成多价疫苗,因此极有可能成为下一个成功应用于人类的新型疫苗.此文对核酸疫苗的研究进展做一综述.%Nucleic acid vaccine is a new type of vaccine,which can deliver foreign genes (DNA or RNA) encoding antigens of interest directly into animal cells,produce antigens through host cell expression system,and further induce immune response in the host.It is reported that nucleic acid vaccine is better than protein vaccine because it is immunogenic and safe,and easy to be modified and manufactured.In practical production,nucleic acid vaccine has many advantages,such as easy preparation and purification,short production cycle,low production cost,and easy to form multivalent vaccines.Therefore,it is hopeful that nucleic acid vaccine will become a successful vaccine for human use.This review summarizes research progress of nucleic acid vaccine.

  14. The essential nature of healthcare databases in critical care medicine

    OpenAIRE

    Martin, Greg S.

    2008-01-01

    Medical databases serve a critical function in healthcare, including the areas of patient care, administration, research and education. The quality and breadth of information collected into existing databases varies tremendously, between databases, between institutions and between national boundaries. The field of critical care medicine could be advanced substantially by the development of comprehensive and accurate databases.

  15. Oracle数据库跨平台数据迁移研究%Research on Cross-Platform Data Migration of Oracle Database

    Institute of Scientific and Technical Information of China (English)

    徐鲁辉; 王芳

    2011-01-01

    From the requirements of data migration,compares the advantages and disadvantages of three standard data backup methods of Oracle database,and analyzes the structure of exported document,and provides the data migration method of Oracle database from UNIX%从数据迁移的实际需求出发,比较Oracle数据库三种标准备份方法的优缺点,分析Oracle导出文件的结构,给出Oracle数据库从Windows平台到UNIX平台数据迁移的实现方法。

  16. An evaluation of Birmingham Own Health® telephone care management service among patients with poorly controlled diabetes. a retrospective comparison with the General Practice Research Database

    Directory of Open Access Journals (Sweden)

    Adab Peymané

    2011-09-01

    Full Text Available Abstract Background Telephone-based care management programmes have been shown to improve health outcomes in some chronic diseases. Birmingham Own Health® is a telephone-based care service (nurse-delivered motivational coaching and support for self-management and lifestyle change for patients with poorly controlled diabetes, delivered in Birmingham, UK. We used a novel method to evaluate its effectiveness in a real-life setting. Methods Retrospective cohort study in the UK. 473 patients aged ≥ 18 years with diabetes enrolled onto Birmingham Own Health® (intervention cohort and with > 90 days follow-up, were each matched by age and sex to up to 50 patients with diabetes registered with the General Practice Research Database (GPRD to create a pool of 21,052 controls (control cohort. Controls were further selected from the main control cohort, matching as close as possible to the cases for baseline test levels, followed by as close as possible length of follow-up (within +/-30 days limits and within +/-90 days baseline test date. The aim was to identify a control group with as similar distribution of prognostic factors to the cases as possible. Effect sizes were computed using linear regression analysis adjusting for age, sex, deprivation quintile, length of follow-up and baseline test levels. Results After adjusting for baseline values and other potential confounders, the intervention showed significant mean reductions among people with diabetes of 0.3% (95%CI 0.1, 0.4% in HbA1c; 3.5 mmHg (1.5, 5.5 in systolic blood pressure, 1.6 mmHg (0.4, 2.7 in diastolic blood pressure and 0.7 unit reduction (0.3, 1.0 in BMI, over a mean follow-up of around 10 months. Only small effects were seen on average on serum cholesterol levels (0.1 mmol/l reduction (0.1, 0.2. More marked effects were seen for each clinical outcome among patients with worse baseline levels. Conclusions Despite the limitations of the study design, the results are consistent with the

  17. Design and internal validation of an obstetric early warning score: secondary analysis of the Intensive Care National Audit and Research Centre Case Mix Programme database.

    Science.gov (United States)

    Carle, C; Alexander, P; Columb, M; Johal, J

    2013-04-01

    We designed and internally validated an aggregate weighted early warning scoring system specific to the obstetric population that has the potential for use in the ward environment. Direct obstetric admissions from the Intensive Care National Audit and Research Centre's Case Mix Programme Database were randomly allocated to model development (n = 2240) or validation (n = 2200) sets. Physiological variables collected during the first 24 h of critical care admission were analysed. Logistic regression analysis for mortality in the model development set was initially used to create a statistically based early warning score. The statistical score was then modified to create a clinically acceptable early warning score. Important features of this clinical obstetric early warning score are that the variables are weighted according to their statistical importance, a surrogate for the FI O2 /Pa O2 relationship is included, conscious level is assessed using a simplified alert/not alert variable, and the score, trigger thresholds and response are consistent with the new non-obstetric National Early Warning Score system. The statistical and clinical early warning scores were internally validated using the validation set. The area under the receiver operating characteristic curve was 0.995 (95% CI 0.992-0.998) for the statistical score and 0.957 (95% CI 0.923-0.991) for the clinical score. Pre-existing empirically designed early warning scores were also validated in the same way for comparison. The area under the receiver operating characteristic curve was 0.955 (95% CI 0.922-0.988) for Swanton et al.'s Modified Early Obstetric Warning System, 0.937 (95% CI 0.884-0.991) for the obstetric early warning score suggested in the 2003-2005 Report on Confidential Enquiries into Maternal Deaths in the UK, and 0.973 (95% CI 0.957-0.989) for the non-obstetric National Early Warning Score. This highlights that the new clinical obstetric early warning score has an excellent ability to

  18. Overview of selected molecular biological databases

    Energy Technology Data Exchange (ETDEWEB)

    Rayl, K.D.; Gaasterland, T.

    1994-11-01

    This paper presents an overview of the purpose, content, and design of a subset of the currently available biological databases, with an emphasis on protein databases. Databases included in this summary are 3D-ALI, Berlin RNA databank, Blocks, DSSP, EMBL Nucleotide Database, EMP, ENZYME, FSSP, GDB, GenBank, HSSP, LiMB, PDB, PIR, PKCDD, ProSite, and SWISS-PROT. The goal is to provide a starting point for researchers who wish to take advantage of the myriad available databases. Rather than providing a complete explanation of each database, we present its content and form by explaining the details of typical entries. Pointers to more complete ``user guides`` are included, along with general information on where to search for a new database.

  19. DMTB: the magnetotactic bacteria database

    Science.gov (United States)

    Pan, Y.; Lin, W.

    2012-12-01

    Magnetotactic bacteria (MTB) are of interest in biogeomagnetism, rock magnetism, microbiology, biomineralization, and advanced magnetic materials because of their ability to synthesize highly ordered intracellular nano-sized magnetic minerals, magnetite or greigite. Great strides for MTB studies have been made in the past few decades. More than 600 articles concerning MTB have been published. These rapidly growing data are stimulating cross disciplinary studies in such field as biogeomagnetism. We have compiled the first online database for MTB, i.e., Database of Magnestotactic Bacteria (DMTB, http://database.biomnsl.com). It contains useful information of 16S rRNA gene sequences, oligonucleotides, and magnetic properties of MTB, and corresponding ecological metadata of sampling sites. The 16S rRNA gene sequences are collected from the GenBank database, while all other data are collected from the scientific literature. Rock magnetic properties for both uncultivated and cultivated MTB species are also included. In the DMTB database, data are accessible through four main interfaces: Site Sort, Phylo Sort, Oligonucleotides, and Magnetic Properties. References in each entry serve as links to specific pages within public databases. The online comprehensive DMTB will provide a very useful data resource for researchers from various disciplines, e.g., microbiology, rock magnetism and paleomagnetism, biogeomagnetism, magnetic material sciences and others.

  20. Based on the Oracle Database Performance Adjustment and Optimization Research%基于Oracle数据库系统的优化与性能调整研究

    Institute of Scientific and Technical Information of China (English)

    刘哲

    2012-01-01

    Oracle performance optimizer will directly affect the efficient operation of database application sys- tem. This article discusses the Oracle database performance optimization objectives, and analyzes the factors affecting performance in every other sides. And the adjustment and optimization of database,memory,I/O, and SQL statements is presented and explained in detail. And finally proved by experiments,after optimiza- tion, Oracle database performance has been improved and enhanced.%指出了Oracle数据库性能直接影响到Oracle数据库应用系统的运行效率,分析了Oracle数据库性能优化的目标及影响Oracle数据库系统性能的因素,探讨了数据库的优化、内存优化、I/O优化和SQL语句优化技术,实验表明:经过优化后,Oracle数据库性能得到了改善和提高。

  1. 基于GIS系统中实时数据库应用的研究%GIS-based system in real-time database application of research

    Institute of Scientific and Technical Information of China (English)

    蔡宇

    2011-01-01

    Real-time database (RTDB) is the products with the increasing of a amount of information in society, and is the core of the information monitoring system (SIS). Global positioning system monitor the operation of a large number of vehicles. The importance of the article is that examining the feasibility of send real-time data into real-time database by large number of vehicles who carrying wireless sensor, and compare the differences of applications in the GIS system between real-time database and relational database.%实时数据库(RTDB)是当今社会信息量不断与日巨增的产物,是信息监控系统(SIS)的核心。GIS全球定位系统中要监控大量的车辆的运行情况,本文的重点是验证大量车辆携带的无线传感器发送实时数据存入实时数据库的可行性,同时比较了实时数据库和关系数据库在GIS系统中应用的差异。

  2. RESEARCH ON ALL NEGATIVE ASSOCIATION RULES MINING IN A DATABASE%数据库中全部负关联规则挖掘研究

    Institute of Scientific and Technical Information of China (English)

    李红; 宗瑜; 解浚源

    2011-01-01

    数据库中关联规则信息是知识的表述形式之一,负关联规则挖掘是数据库关联信息挖掘的重要研究内容,具有广泛的应用范围.现有的挖掘方法不能获取数据库中全部的负关联规则,考虑从数据库中提取全部的负关联规则,通过(1)扫描数据库建立数据库频繁模式树DFP-tree( Database Frequent Pattern tree);(2)在精简DFP-tree的基础上获取全部极小非频繁项集ASI;(3)对ASI中极大频繁项集的向上闭包,得到全部非频繁项集;(4)在此基础上采用相关度作为规则兴趣度量之一提取负关联规则.理论和实验表明算法的正确性和效率.%In a database, associated rule information is one of the representation formats for knowledge. Negative association rule mining is so important to study in database association information mining that it bears wide application value. Existing mining approaches can not obtain all negative rules from a database. The paper considers to extract all negative association rules from a database through: (1) scanning the database to build a database frequent pattern tree called DFP-tree; (2) acquiring based on pruning the DFP-tree all small infrequent itemsets; (3) acquiring via upward closure packets of large frequent itemsets in ASI all infrequent itemsets; (4) based on the previous 3 steps adopting correlation metric as one of rule interest measurements to extract negative association rules. Theories and experiments validate the correctness and efficiency of the presented algorithm.

  3. The Danish Anaesthesia Database

    Directory of Open Access Journals (Sweden)

    Antonsen K

    2016-10-01

    Full Text Available Kristian Antonsen,1 Charlotte Vallentin Rosenstock,2 Lars Hyldborg Lundstrøm2 1Board of Directors, Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Capital Region of Denmark, Denmark; 2Department of Anesthesiology, Copenhagen University Hospital, Nordsjællands Hospital-Hillerød, Capital Region of Denmark, Denmark Aim of database: The aim of the Danish Anaesthesia Database (DAD is the nationwide collection of data on all patients undergoing anesthesia. Collected data are used for quality assurance, quality development, and serve as a basis for research projects. Study population: The DAD was founded in 2004 as a part of Danish Clinical Registries (Regionernes Kliniske Kvalitetsudviklings Program [RKKP]. Patients undergoing general anesthesia, regional anesthesia with or without combined general anesthesia as well as patients under sedation are registered. Data are retrieved from public and private anesthesia clinics, single-centers as well as multihospital corporations across Denmark. In 2014 a total of 278,679 unique entries representing a national coverage of ~70% were recorded, data completeness is steadily increasing. Main variable: Records are aggregated for determining 13 defined quality indicators and eleven defined complications all covering the anesthetic process from the preoperative assessment through anesthesia and surgery until the end of the postoperative recovery period. Descriptive data: Registered variables include patients' individual social security number (assigned to all Danes and both direct patient-related lifestyle factors enabling a quantification of patients' comorbidity as well as variables that are strictly related to the type, duration, and safety of the anesthesia. Data and specific data combinations can be extracted within each department in order to monitor patient treatment. In addition, an annual DAD report is a benchmark for departments nationwide. Conclusion: The DAD is covering the

  4. 基于数据库分类的deep web爬行器研究%Research on Deep Web Crawler Based on Database Classification

    Institute of Scientific and Technical Information of China (English)

    郭少友; 赵善义; 李建平; 王斌

    2011-01-01

    在现有相关研究的基础上,设计一种基于数据库分类的deepweb爬行器。该爬行器首先从抓取的网页中识别出deepweb数据库的入口表单,然后采用查询探测方法对数据库进行自动分类,并根据分类结果来选取一组合适的关键词作为查询词,自动填写入口表单中的文本框并向数据库提出查询请求。实验结果表明,基于数据库分类的deepweb爬行器的爬行效果要优于基于指定查询词的deepweb行器的爬行效果。%On the basis of related work, this paper designs a deep web crawler based on database classification. First, it identifies the entry forms of deep web databases from downloaded pages, and then classifies deep web databases with query probing . According to the classification results, some proper keywords are selected as query terms, and automatically filled in the text boxes of these forms to query deep web databases. The experimental results show that the crawling effect of the crawler based on database classification is superior to that of the crawler based on specified query terms.

  5. The COMPADRE Plant Matrix Database

    DEFF Research Database (Denmark)

    2014-01-01

    COMPADRE contains demographic information on hundreds of plant species. The data in COMPADRE are in the form of matrix population models and our goal is to make these publicly available to facilitate their use for research and teaching purposes. COMPADRE is an open-access database. We only request...

  6. Protein-Protein Interaction Databases

    DEFF Research Database (Denmark)

    Szklarczyk, Damian; Jensen, Lars Juhl

    2015-01-01

    of research are explored. Here we present an overview of the most widely used protein-protein interaction databases and the methods they employ to gather, combine, and predict interactions. We also point out the trade-off between comprehensiveness and accuracy and the main pitfall scientists have to be aware...

  7. REPLIKASI UNIDIRECTIONAL PADA HETEROGEN DATABASE

    Directory of Open Access Journals (Sweden)

    Hendro Nindito

    2013-11-01

    where development can be done quickly and testing of working models of the interaction process is done through repeated. From this research it is obtained that the database replication technology using Oracle Golden Gate can be applied in heterogeneous environments in real time as well.

  8. Metadata queries for complex database systems

    OpenAIRE

    O'Connor, Gerald

    2004-01-01

    Federated Database Management Systems (FDBS) are very complex. Component databases can be heterogeneous, autonomous and distributed, accounting for these different characteristics in building a FDBS is a difficult engineering problem. The Common Data Model (CDM) is what is used to represent the data in the FDBS. It must be semantically rich to correctly represent the data from diverse component databases which differ in structure, datamodel, semantics and content. In this research project we ...

  9. A New Improved Algorithm for Distributed Databases

    OpenAIRE

    K. Karpagam; Balasubramanian, R

    2011-01-01

    The development of web, data stores from disparate sources has contributed to the growth of very large data sources and distributed systems. Large amounts of data are stored in distributed databases, since it is difficult to store these data in single place on account of communication, efficiency and security. Researches on mining association rules in distributed databases have more relevance in today’s world. Recently, as the need to mine patterns across distributed databases has grown, Dist...

  10. An Algorithm for Building an Electronic Database

    OpenAIRE

    Cohen, Wess A.; Gayle, Lloyd B.; Patel, Nima P.

    2016-01-01

    Objective: We propose an algorithm on how to create a prospectively maintained database, which can then be used to analyze prospective data in a retrospective fashion. Our algorithm provides future researchers a road map on how to set up, maintain, and use an electronic database to improve evidence-based care and future clinical outcomes. Methods: The database was created using Microsoft Access and included demographic information, socioeconomic information, and intraoperative and postoperati...

  11. Cell Centred Database (CCDB)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Cell Centered Database (CCDB) is a web accessible database for high resolution 2D, 3D and 4D data from light and electron microscopy, including correlated...

  12. AIDSinfo Drug Database

    Science.gov (United States)

    ... Widgets Order Publications Skip Nav AIDS info Drug Database Home > Drugs Español small medium large Text Size ... health care providers and patients. Search the Drug Database Help × Search by drug name Performs a search ...

  13. Web database development

    OpenAIRE

    Tsardas, Nikolaos A.

    2001-01-01

    This thesis explores the concept of Web Database Development using Active Server Pages (ASP) and Java Server Pages (JSP). These are among the leading technologies in the web database development. The focus of this thesis was to analyze and compare the ASP and JSP technologies, exposing their capabilities, limitations, and differences between them. Specifically, issues related to back-end connectivity using Open Database Connectivity (ODBC) and Java Database Connectivity (JDBC), application ar...

  14. IP Geolocation Databases: Unreliable?

    OpenAIRE

    Poese, Ingmar; Uhlig, Steve; Kaafar, Mohamed Ali; Donnet, Benoît; Gueye, Bamba

    2011-01-01

    The most widely used technique for IP geolocation con- sists in building a database to keep the mapping between IP blocks and a geographic location. Several databases are available and are frequently used by many services and web sites in the Internet. Contrary to widespread belief, geolo- cation databases are far from being as reliable as they claim. In this paper, we conduct a comparison of several current geolocation databases -both commercial and free- to have an insight of the limitation...

  15. Refactoring of a Database

    OpenAIRE

    Dsousa, Ayeesha; Bhatia, Shalini

    2009-01-01

    The technique of database refactoring is all about applying disciplined and controlled techniques to change an existing database schema. The problem is to successfully create a Database Refactoring Framework for databases. This paper concentrates on the feasibility of adapting this concept to work as a generic template. To retain the constraints regardless of the modifications to the metadata, the paper proposes a MetaData Manipulation Tool to facilitate change. The tool adopts a Template Des...

  16. Database Programming Languages

    DEFF Research Database (Denmark)

    This volume contains the proceedings of the 11th International Symposium on Database Programming Languages (DBPL 2007), held in Vienna, Austria, on September 23-24, 2007. DBPL 2007 was one of 15 meetings co-located with VLBD (the International Conference on Very Large Data Bases). DBPL continues...... to present the very best work at the intersection of dataase and programming language research. The proceedings include a paper based on the invited talk by Wenfie Fan and the 16 contributed papers that were selected by at least three members of the program committee. In addition, the program commitee sought...... the opinions of additional referees selected becauce of their expertise on particular topics. The final selection of papers was made during last week of July. We would like to thank all of the aurhors who submitted papers to the conference, and the members of the program committee  for their excellent work...

  17. Automated Oracle database testing

    CERN Document Server

    CERN. Geneva

    2014-01-01

    Ensuring database stability and steady performance in the modern world of agile computing is a major challenge. Various changes happening at any level of the computing infrastructure: OS parameters & packages, kernel versions, database parameters & patches, or even schema changes, all can potentially harm production services. This presentation shows how an automatic and regular testing of Oracle databases can be achieved in such agile environment.

  18. 网络环境下的非结构化数据库应用研究%Application Research on Unstructured Database in the Network

    Institute of Scientific and Technical Information of China (English)

    王颖; 李建敏

    2015-01-01

    Based on unstructured database technology,this paper analyzes the current situation of data⁃base application in the network environment,discusses the construction of network databases,analysis of un⁃structured data,and an application example is used for explanation.%本文从非结构化数据库技术出发,分析了网络环境下数据库应用现状,探讨了网络数据库的建设、非结构化数据的分析,并以一个具体应用实例进行了说明。

  19. Status Quo and Prospect on Mobile Database Security

    OpenAIRE

    Tao Zhang; Shi Xing-jun

    2013-01-01

    Mobile database is a specialized class of distributed systems. There are some security challenges because of the dispersed nature of the mobile database application and hardware deviceconstraints. Therefore, the security issue of mobile database is analyzed in this paper. We will research the security in terms of mobile device, operating system on mobile device, mobile network and mobile database. Moreover, various security vulnerabilities on mobile database is recognized. Some appropriate t...

  20. Research of Parallel Query Processing Algorithm In Object-Oriented Database%面向对象数据库的并行查询处理

    Institute of Scientific and Technical Information of China (English)

    王意洁; 王勇军; 胡守仁

    2000-01-01

    In this paper, according to the features of the object-oriented database and its query, the stage-by-stage executing strategy,the class-based hybrid data placement strategy, the mark-based data operation parallel executing algorithm and the semi-join-based parallel query processing algorithm are proposed.the correctness of the algorithm is proved.and the results of performance evaluation are given.

  1. Oceans of Data: In what ways can learning research inform the development of electronic interfaces and tools for use by students accessing large scientific databases?

    Science.gov (United States)

    Krumhansl, R. A.; Foster, J.; Peach, C. L.; Busey, A.; Baker, I.

    2012-12-01

    The practice of science and engineering is being revolutionized by the development of cyberinfrastructure for accessing near real-time and archived observatory data. Large cyberinfrastructure projects have the potential to transform the way science is taught in high school classrooms, making enormous quantities of scientific data available, giving students opportunities to analyze and draw conclusions from many kinds of complex data, and providing students with experiences using state-of-the-art resources and techniques for scientific investigations. However, online interfaces to scientific data are built by scientists for scientists, and their design can significantly impede broad use by novices. Knowledge relevant to the design of student interfaces to complex scientific databases is broadly dispersed among disciplines ranging from cognitive science to computer science and cartography and is not easily accessible to designers of educational interfaces. To inform efforts at bridging scientific cyberinfrastructure to the high school classroom, Education Development Center, Inc. and the Scripps Institution of Oceanography conducted an NSF-funded 2-year interdisciplinary review of literature and expert opinion pertinent to making interfaces to large scientific databases accessible to and usable by precollege learners and their teachers. Project findings are grounded in the fundamentals of Cognitive Load Theory, Visual Perception, Schemata formation and Universal Design for Learning. The Knowledge Status Report (KSR) presents cross-cutting and visualization-specific guidelines that highlight how interface design features can address/ ameliorate challenges novice high school students face as they navigate complex databases to find data, and construct and look for patterns in maps, graphs, animations and other data visualizations. The guidelines present ways to make scientific databases more broadly accessible by: 1) adjusting the cognitive load imposed by the user

  2. Research on Design of Data Element Model in Flash Memory Database Wear Balanced Control%闪存数据库磨损均衡控制中数据元模型设计研究

    Institute of Scientific and Technical Information of China (English)

    胡萍

    2015-01-01

    Web flash memory database wear data element is the important content of research on information extraction and optimization. From two aspects: flash memory database wear segmentation technology and wear characteristic extraction and characteristic presentation, research is made on maximum flash memory wear matching method and flash memory wear vector space model (VSM) to optimize the data element model in flash memory database wear balanced control.%Web闪存数据库磨损数据元是信息提取与优化研究的重要内容.本文主要从闪存数据库磨损切分技术和磨损特征提取与特征表示两方面入手,对最大闪存磨损匹配法和闪存磨损向量空间模型(VSM)进行研究改进,以实现闪存磨损均衡控制中数据元模型的优化设计.

  3. Teaching Research of Database Theory and Application Course%《数据库原理及应用》课程的教学法研究

    Institute of Scientific and Technical Information of China (English)

    张燕; 毛莉君

    2012-01-01

    According to the current database technology penetration by a computer professional to non-computer professional features,combined with each specialized in different professional direction and goal,the purpose of teaching methods and teaching points from the database of professional learning,and cultivate the talent is more suitable for the development of modem database technology to erdianee the students' interest and practical ability.%针对目前数据库技术已经由计算机专业渗透到了非计算机专业的特点,结合每个专业不同的专业方向和培养目标,从各专业的数据库学习目的、教学的方法和教学要点等方面进行了探讨,以提高学生的学习兴趣和动手能力,培养出更适合现代数据库技术发展的人才。

  4. SQL Server Database Intrusion Detection System Research%SQL Server数据库入侵检测系统的研究

    Institute of Scientific and Technical Information of China (English)

    郭可

    2016-01-01

    with the rapid development of network technology, the Internet has spread in the life of people, network attack has be-come a developing needs to solve an important issue. The traditional firewall technology already cannot satisfy the needs of In-ternet security, intrusion detection technology in improving the security of network database can provide effective protection. In this paper, the intrusion detection system and database intrusion detection technology has carried on the simple analysis, SQL server database intrusion detection system design method is proposed.%随着网络技术的迅速发展,互联网在人们的生活中已经普及,网络攻击也成为网络发展中需要解决的一个重要的课题。传统的防火墙技术已经不能满足互联网安全的需要,数据库的入侵检测技术在提高网络的安全性方面可以提供有效的保障。该文对入侵检测系统和数据库入侵检测技术进行了简单的分析,提出了SQL server数据库入侵检测系统设计方法。

  5. CTD_DATABASE - Cascadia tsunami deposit database

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Cascadia Tsunami Deposit Database contains data on the location and sedimentological properties of tsunami deposits found along the Cascadia margin. Data have...

  6. Knowledge discovery in variant databases using inductive logic programming.

    Science.gov (United States)

    Nguyen, Hoan; Luu, Tien-Dao; Poch, Olivier; Thompson, Julie D

    2013-01-01

    Understanding the effects of genetic variation on the phenotype of an individual is a major goal of biomedical research, especially for the development of diagnostics and effective therapeutic solutions. In this work, we describe the use of a recent knowledge discovery from database (KDD) approach using inductive logic programming (ILP) to automatically extract knowledge about human monogenic diseases. We extracted background knowledge from MSV3d, a database of all human missense variants mapped to 3D protein structure. In this study, we identified 8,117 mutations in 805 proteins with known three-dimensional structures that were known to be involved in human monogenic disease. Our results help to improve our understanding of the relationships between structural, functional or evolutionary features and deleterious mutations. Our inferred rules can also be applied to predict the impact of any single amino acid replacement on the function of a protein. The interpretable rules are available at http://decrypthon.igbmc.fr/kd4v/.

  7. Performance related issues in distributed database systems

    Science.gov (United States)

    Mukkamala, Ravi

    1991-01-01

    The key elements of research performed during the year long effort of this project are: Investigate the effects of heterogeneity in distributed real time systems; Study the requirements to TRAC towards building a heterogeneous database system; Study the effects of performance modeling on distributed database performance; and Experiment with an ORACLE based heterogeneous system.

  8. Database Cancellation: The "Hows" and "Whys"

    Science.gov (United States)

    Shapiro, Steven

    2012-01-01

    Database cancellation is one of the most difficult tasks performed by a librarian. This may seem counter-intuitive but, psychologically, it is certainly true. When a librarian or a team of librarians has invested a great deal of time doing research, talking to potential users, and conducting trials before deciding to subscribe to a database, they…

  9. The Life Support Database system

    Science.gov (United States)

    Likens, William C.

    1991-01-01

    The design and implementation of the database system are described with specific reference to data available from the Build-1 version and techniques for its utilization. The review of the initial documents for the Life Support Database is described in terms of title format and sequencing, and the users are defined as participants in NASA-sponsored life-support research. The software and hardware selections are based respectively on referential integrity and compatibility, and the implementation of the user interface is achieved by means of an applications-programming tool. The current Beta-Test implementation of the system includes several thousand acronyms and bibliographic references as well as chemical properties and exposure limits, equipment, construction materials, and mission data. In spite of modifications in the database the system is found to be effective and a potentially significant resource for the aerospace community.

  10. Genotyping and interpretation of STR-DNA: Low-template, mixtures and database matches-Twenty years of research and development.

    Science.gov (United States)

    Gill, Peter; Haned, Hinda; Bleka, Oyvind; Hansson, Oskar; Dørum, Guro; Egeland, Thore

    2015-09-01

    The introduction of Short Tandem Repeat (STR) DNA was a revolution within a revolution that transformed forensic DNA profiling into a tool that could be used, for the first time, to create National DNA databases. This transformation would not have been possible without the concurrent development of fluorescent automated sequencers, combined with the ability to multiplex several loci together. Use of the polymerase chain reaction (PCR) increased the sensitivity of the method to enable the analysis of a handful of cells. The first multiplexes were simple: 'the quad', introduced by the defunct UK Forensic Science Service (FSS) in 1994, rapidly followed by a more discriminating 'six-plex' (Second Generation Multiplex) in 1995 that was used to create the world's first national DNA database. The success of the database rapidly outgrew the functionality of the original system - by the year 2000 a new multiplex of ten-loci was introduced to reduce the chance of adventitious matches. The technology was adopted world-wide, albeit with different loci. The political requirement to introduce pan-European databases encouraged standardisation - the development of European Standard Set (ESS) of markers comprising twelve-loci is the latest iteration. Although development has been impressive, the methods used to interpret evidence have lagged behind. For example, the theory to interpret complex DNA profiles (low-level mixtures), had been developed fifteen years ago, but only in the past year or so, are the concepts starting to be widely adopted. A plethora of different models (some commercial and others non-commercial) have appeared. This has led to a confusing 'debate' about the 'best' to use. The different models available are described along with their advantages and disadvantages. A section discusses the development of national DNA databases, along with details of an associated controversy to estimate the strength of evidence of matches. Current methodology is limited to

  11. Nuclear power economic database

    International Nuclear Information System (INIS)

    Nuclear power economic database (NPEDB), based on ORACLE V6.0, consists of three parts, i.e., economic data base of nuclear power station, economic data base of nuclear fuel cycle and economic database of nuclear power planning and nuclear environment. Economic database of nuclear power station includes data of general economics, technique, capital cost and benefit, etc. Economic database of nuclear fuel cycle includes data of technique and nuclear fuel price. Economic database of nuclear power planning and nuclear environment includes data of energy history, forecast, energy balance, electric power and energy facilities

  12. An Interoperable Cartographic Database

    Directory of Open Access Journals (Sweden)

    Slobodanka Ključanin

    2007-05-01

    Full Text Available The concept of producing a prototype of interoperable cartographic database is explored in this paper, including the possibilities of integration of different geospatial data into the database management system and their visualization on the Internet. The implementation includes vectorization of the concept of a single map page, creation of the cartographic database in an object-relation database, spatial analysis, definition and visualization of the database content in the form of a map on the Internet. 

  13. Acid rain research[NIVA contributions to ACID REIGN '95? Conference in Gothenburg, Sweden, 26-30 June 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    The conference dealt with various sources, aspects and present and future consequences of pollution, particularly acid precipitation on the environment especially on the terrestrial and aquatic parts, with the focus on acidification. Surveys of the extent of the problems were presented. Various methods of reversing the effects are dealt with. Much attention was focused on various water systems such as rivers, lakes, surface waters and ground water and consequences of pollution chemically, geologically, biologically and botanically. The problems of global warming and changes were also focused upon. The origins of pollutants were discussed.

  14. The new IAGOS Database Portal

    Science.gov (United States)

    Boulanger, Damien; Gautron, Benoit; Thouret, Valérie; Fontaine, Alain

    2016-04-01

    IAGOS (In-service Aircraft for a Global Observing System) is a European Research Infrastructure which aims at the provision of long-term, regular and spatially resolved in situ observations of the atmospheric composition. IAGOS observation systems are deployed on a fleet of commercial aircraft. The IAGOS database is an essential part of the global atmospheric monitoring network. It contains IAGOS-core data and IAGOS-CARIBIC (Civil Aircraft for the Regular Investigation of the Atmosphere Based on an Instrument Container) data. The IAGOS Database Portal (http://www.iagos.fr, damien.boulanger@obs-mip.fr) is part of the French atmospheric chemistry data center AERIS (http://www.aeris-data.fr). The new IAGOS Database Portal has been released in December 2015. The main improvement is the interoperability implementation with international portals or other databases in order to improve IAGOS data discovery. In the frame of the IGAS project (IAGOS for the Copernicus Atmospheric Service), a data network has been setup. It is composed of three data centers: the IAGOS database in Toulouse; the HALO research aircraft database at DLR (https://halo-db.pa.op.dlr.de); and the CAMS data center in Jülich (http://join.iek.fz-juelich.de). The CAMS (Copernicus Atmospheric Monitoring Service) project is a prominent user of the IGAS data network. The new portal provides improved and new services such as the download in NetCDF or NASA Ames formats, plotting tools (maps, time series, vertical profiles, etc.) and user management. Added value products are available on the portal: back trajectories, origin of air masses, co-location with satellite data, etc. The link with the CAMS data center, through JOIN (Jülich OWS Interface), allows to combine model outputs with IAGOS data for inter-comparison. Finally IAGOS metadata has been standardized (ISO 19115) and now provides complete information about data traceability and quality.

  15. Electronic database of arterial aneurysms

    Directory of Open Access Journals (Sweden)

    Fabiano Luiz Erzinger

    2014-12-01

    Full Text Available Background:The creation of an electronic database facilitates the storage of information, as well as streamlines the exchange of data, making easier the exchange of knowledge for future research.Objective:To construct an electronic database containing comprehensive and up-to-date clinical and surgical data on the most common arterial aneurysms, to help advance scientific research.Methods:The most important specialist textbooks and articles found in journals and on internet databases were reviewed in order to define the basic structure of the protocol. Data were computerized using the SINPE© system for integrated electronic protocols and tested in a pilot study.Results:The data entered onto the system was first used to create a Master protocol, organized into a structure of top-level directories covering a large proportion of the content on vascular diseases as follows: patient history; physical examination; supplementary tests and examinations; diagnosis; treatment; and clinical course. By selecting items from the Master protocol, Specific protocols were then created for the 22 arterial sites most often involved by aneurysms. The program provides a method for collection of data on patients including clinical characteristics (patient history and physical examination, supplementary tests and examinations, treatments received and follow-up care after treatment. Any information of interest on these patients that is contained in the protocol can then be used to query the database and select data for studies.Conclusions:It proved possible to construct a database of clinical and surgical data on the arterial aneurysms of greatest interest and, by adapting the data to specific software, the database was integrated into the SINPE© system, thereby providing a standardized method for collection of data on these patients and tools for retrieving this information in an organized manner for use in scientific studies.

  16. RPG: the Ribosomal Protein Gene database

    OpenAIRE

    Nakao, Akihiro; Yoshihama, Maki; Kenmochi, Naoya

    2004-01-01

    RPG (http://ribosome.miyazaki-med.ac.jp/) is a new database that provides detailed information about ribosomal protein (RP) genes. It contains data from humans and other organisms, including Drosophila melanogaster, Caenorhabditis elegans, Saccharo myces cerevisiae, Methanococcus jannaschii and Escherichia coli. Users can search the database by gene name and organism. Each record includes sequences (genomic, cDNA and amino acid sequences), intron/exon structures, genomic locations and informa...

  17. General database for ground water site information.

    Science.gov (United States)

    de Dreuzy, Jean-Raynald; Bodin, Jacques; Le Grand, Hervé; Davy, Philippe; Boulanger, Damien; Battais, Annick; Bour, Olivier; Gouze, Philippe; Porel, Gilles

    2006-01-01

    In most cases, analysis and modeling of flow and transport dynamics in ground water systems require long-term, high-quality, and multisource data sets. This paper discusses the structure of a multisite database (the H+ database) developed within the scope of the ERO program (French Environmental Research Observatory, http://www.ore.fr). The database provides an interface between field experimentalists and modelers, which can be used on a daily basis. The database structure enables the storage of a large number of data and data types collected from a given site or multiple-site network. The database is well suited to the integration, backup, and retrieval of data for flow and transport modeling in heterogeneous aquifers. It relies on the definition of standards and uses a templated structure, such that any type of geolocalized data obtained from wells, hydrological stations, and meteorological stations can be handled. New types of platforms other than wells, hydrological stations, and meteorological stations, and new types of experiments and/or parameters could easily be added without modifying the database structure. Thus, we propose that the database structure could be used as a template for designing databases for complex sites. An example application is the H+ database, which gathers data collected from a network of hydrogeological sites associated with the French Environmental Research Observatory.

  18. 数控监控系统中数据库系统的研究%The Research of Database System in CNC Monitoring System

    Institute of Scientific and Technical Information of China (English)

    徐凡; 黄道平; 刘少君

    2013-01-01

    基于以太网的数控群集监控系统中,为保存每台数控系统的报警信息和加工信息等,在监控系统中建立数据库系统.在对数控群集监控系统的需求与特点进行分析的基础上,提出了一种跨平台的数据库系统解决方案.该方案主要包括网络传输、数据处理和人机交互界面三大部分.网络文件传输的软件体系采用C/S结构,数据库管理系统采用MySQL,整个数据库系统使用Python语言进行开发.用Python连接MySQL,对获取的数据进行处理,将处理结果显示到人机交互界面上,效果较好.%To save messages, such as warn message and work message, of the CNC Cluster Monitoring system based on Ethernet, Establish an database system in moniteoring system. On the study of the needs and features of the monitoring system, proposed a solution of muti-platform database system. The solution includes 3 parts: network transmission, data processing, man machine interface. Adopt C/S model as the network transmission software structure, MySQL as the DBMS and Python as the language to develop the whole database system. Use Python to link MySQL, then to process the data gotten from MySQL, and then to show the processing result on the GUI.

  19. Spatial Distribution of Methanesulphonic Acid in the Arctic Aerosol Collected during the Chinese Arctic Research Expedition

    Directory of Open Access Journals (Sweden)

    Peipei Ye

    2015-05-01

    Full Text Available Methanesulphonic acid (MSA, mainly derived from marine biogenic emissions has been frequently used to estimate the marine biogenic contribution. However, there are few reports on MSA over the Arctic Ocean, especially the central Arctic Ocean. Here, we analyzed MSA in aerosol samples collected over the ocean and seas during the Chinese Arctic Research Expedition (CHINARE 2012 using ion chromatography. The aerosol MSA concentrations over the Arctic Ocean varied considerably and ranged from non-detectable (ND to 229 ng/m3, with an average of 27 ± 54 ng/m3 (median: 10 ng/m3. We found the distribution of aerosol MSA exhibited an obvious regional variation, which was affected by biotic and abiotic factors. High values were generally observed in the Norwegian Sea; this phenomenon was attributed to high rates of phytoplankton primary productivity and dimethylsulfide (DMS fluxes in this region. Concentrations over the pack ice region in the central Arctic Ocean were generally lower than over the open waters at the ice edge in the Chukchi Sea. This difference was the mainly caused by sea ice. In addition, we found that higher MSA concentrations were associated with warmer sea surface temperature (SST.

  20. 时空数据库索引机制研究%Research of Index Mechanisms in Spatio-temporal Databases

    Institute of Scientific and Technical Information of China (English)

    黄曙荣; 秦小麟

    2003-01-01

    Spatio-temporal database manages the large amount of spatial objects that change over time. It is necessary to query the spatio-temporal objects of the past and the current and to anticipate the future of spatio-temporal objects. It Is important to design an efficient index mechanism for accessing the spatio-temporal data efficiently. The paper analyzes the features of the spatio-temporal objects, studies the methods of spatio-temporal index mechanisms, classifies the index mechanisms, and discusses the key technologies of spatio-temporal indexes. And it also presents the index methods of STADBS that we are studying.

  1. Research Establish the alignment results database%基于定线成果数据库建立的研究

    Institute of Scientific and Technical Information of China (English)

    刘晓利

    2014-01-01

    本文详细地论述了我院建立定线成果数据库的设计思想、建库实施方法,实现了我院的定线成果资料标准化、数字化、自动化的信息管理。%This paper discusses in detail the hospital establish alignment results database design idea and implementation method of building warehouse, realized our alignment results data standardization, digitization, automation of information management.

  2. Research on Data Mining of Computer Virus Database%计算机病毒数据库的数据挖掘研究

    Institute of Scientific and Technical Information of China (English)

    郑克忠

    2012-01-01

    本文论述了计算机病毒数据库的数据挖掘方法,为检测、识别计算机病毒以及预防和清除计算机病毒,提供了理论依据和较好的办法.%This paper discusses method of data mining of computer virus database; which provides theoretical basis and preferable means for detecting and identifying computer virus and preventing and removing computer virus.

  3. Research, development, and demonstration of lead-acid batteries for electric-vehicle propulsion. Annual report for 1982

    Energy Technology Data Exchange (ETDEWEB)

    Bowman, D.E.

    1983-08-01

    Research programs on lead-acid batteries are reported that cover active materials utilization, active material integrity, and some technical support projects. Processing problems were encountered and corrected. Components and materials, a lead-plastic composite grid, cell designs, and deliverables are described. Cell testing is discussed, as well as battery subsystems, including fuel gage, thermal management, and electrolyte circulation. (LEW)

  4. Database structure and file layout of Nuclear Power Plant Database. Database for design information on Light Water Reactors in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, Nobuo [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Izumi, Fumio

    1995-12-01

    The Nuclear Power Plant Database (PPD) has been developed at the Japan Atomic Energy Research Institute (JAERI) to provide plant design information on domestic Light Water Reactors (LWRs) to be used for nuclear safety research and so forth. This database can run on the main frame computer in the JAERI Tokai Establishment. The PPD contains the information on the plant design concepts, the numbers, capacities, materials, structures and types of equipment and components, etc, based on the safety analysis reports of the domestic LWRs. This report describes the details of the PPD focusing on the database structure and layout of data files so that the users can utilize it efficiently. (author).

  5. Database design and database administration for a kindergarten

    OpenAIRE

    Vítek, Daniel

    2009-01-01

    The bachelor thesis deals with creation of database design for a standard kindergarten, installation of the designed database into the database system Oracle Database 10g Express Edition and demonstration of the administration tasks in this database system. The verification of the database was proved by a developed access application.

  6. Research on Establishing Microsoft Access Database of Geographical Coordinate Grids%构建大地坐标格网数据库的方法研究

    Institute of Scientific and Technical Information of China (English)

    陈秀萍; 吕翠华; 黄彦锋; 郭忠明

    2012-01-01

    Now usual business software can be used to create geographic coordinate grids with stand longitude and latitude interval, but can not create grids with any interval . Grids with any interval is important in the field of surveying ang maping producing, inspection and management . Two methods are introduced to build datdbase with any range,any interval grids. In order to use SQL and assign valve for the grids easily the Microsoft Access is adopted for the database format. Many words are used to introduce how to build geographic coordinate grid database and assemblage mapindex automatically using Python code.%目前常见的商业软件能较好地处理标准分幅的经纬格网,却不能方便地生成任意经纬格网.但任意格网在测绘生产、质检、管理工作中是重要的.介绍了两种构建任意范围、任意格网数据库的方法.数据库格式采用Microsoft Access数据库文件(Mdb),便于使用SQL语句在不同图层间进行属性赋值.重点介绍了如何运用Python编程自动构建大地坐标格网线和结合图表表示.

  7. Genome Statute and Legislation Database

    Science.gov (United States)

    ... Database Welcome to the Genome Statute and Legislation Database The Genome Statute and Legislation Database is comprised ... the National Society of Genetic Counselors . Search the Database Search Tips You may select one or more ...

  8. Hazard Analysis Database Report

    CERN Document Server

    Grams, W H

    2000-01-01

    The Hazard Analysis Database was developed in conjunction with the hazard analysis activities conducted in accordance with DOE-STD-3009-94, Preparation Guide for U S . Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports, for HNF-SD-WM-SAR-067, Tank Farms Final Safety Analysis Report (FSAR). The FSAR is part of the approved Authorization Basis (AB) for the River Protection Project (RPP). This document describes, identifies, and defines the contents and structure of the Tank Farms FSAR Hazard Analysis Database and documents the configuration control changes made to the database. The Hazard Analysis Database contains the collection of information generated during the initial hazard evaluations and the subsequent hazard and accident analysis activities. The Hazard Analysis Database supports the preparation of Chapters 3 ,4 , and 5 of the Tank Farms FSAR and the Unreviewed Safety Question (USQ) process and consists of two major, interrelated data sets: (1) Hazard Analysis Database: Data from t...

  9. Database Optimizing Services

    Directory of Open Access Journals (Sweden)

    Adrian GHENCEA

    2010-12-01

    Full Text Available Almost every organization has at its centre a database. The database provides support for conducting different activities, whether it is production, sales and marketing or internal operations. Every day, a database is accessed for help in strategic decisions. The satisfaction therefore of such needs is entailed with a high quality security and availability. Those needs can be realised using a DBMS (Database Management System which is, in fact, software for a database. Technically speaking, it is software which uses a standard method of cataloguing, recovery, and running different data queries. DBMS manages the input data, organizes it, and provides ways of modifying or extracting the data by its users or other programs. Managing the database is an operation that requires periodical updates, optimizing and monitoring.

  10. Effects of diphosphonic acid on ilmenorutile collecting property and research of action mechanism

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The effects of several collectors and their dosage on pure ilmenorutile at different pH values were studied and the collecting strength of several representative collectors was investigated. The experimental results indicate that diphosphonic acid is a good collector for ilmenorutile and the recovery of ilmenorutile ranges from 90.87% to 91.70% when the pulp pH value is 2.0-4.0 and the dosage is 75mg/L. Thesequence of collecting ability for several collectors is as follows: diphosphonic acid > TF279 > cyclic alkyl hydroximic acid > benzyl arsenic acid > salicylic hydroximic acid > alkyl hydroximic acid. Meanwhile, IAS (infrared absorption spectrum) and XPS (X-ray photoelectron spectroscopy) were used to detect and analyze the action mechanism of diphosphonic acid on ilmenorutile. IAS results showed that the characterid between wave numeber and cm, and diphosphonic acid had adsorbed on the surface of ilmenorutile. XPS results indicated that the binding energy of P2P peak of ilmenorutile had changed 0.45eV after treated by diphosphonic acid. This proves that the adsorption is mainly chemical adsorption.

  11. 基于参数化Petri网的主动数据库的行为研究%Research of Active Database System's Behavior Based on Parametrized Petri Net

    Institute of Scientific and Technical Information of China (English)

    王自强; 冯博琴

    2003-01-01

    Although the necessity for ADS's(Active Database System)capabilities has been identified for a wide of ap-plications ,questions have been raised on the robustness of these systems . A major concern in ADS research is the is-sue of ECA rules termination . A multiple abstraction model,namely Parametrized Petri Net(PPN)is introduced as atool to model and analyze ADS's behavior,modeling flexibility of ADS is enhanced . In addition ,procedures to indi-cate ECA rules termination in an ADS is presented based on examining properties of the corresponding PPN model.

  12. The abroad research status of chinese anti-neoplasms herbs basing on Pubmed database%基于Pubmed国外抗肿瘤中药的研究现状

    Institute of Scientific and Technical Information of China (English)

    何巍; 赵英凯; 李凤玲; 杨硕; 董燕; 尹仁芳

    2010-01-01

    This article is basing on the literatures of Pubmed database, collecting and analyzing recent-year abroad researches that related on Chinese anti-neoplasms herbs and botanicals.%本文以PUBMED收录的文献为依据,通过整理、分析近年来国外有关中药及其植物药抗肿瘤的相关研究,探讨中草药治疗癌症的优势及今后的研究方向.

  13. Supply Chain Initiatives Database

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-11-01

    The Supply Chain Initiatives Database (SCID) presents innovative approaches to engaging industrial suppliers in efforts to save energy, increase productivity and improve environmental performance. This comprehensive and freely-accessible database was developed by the Institute for Industrial Productivity (IIP). IIP acknowledges Ecofys for their valuable contributions. The database contains case studies searchable according to the types of activities buyers are undertaking to motivate suppliers, target sector, organization leading the initiative, and program or partnership linkages.

  14. Database management systems

    CERN Document Server

    Pallaw, Vijay Krishna

    2010-01-01

    The text covers the fundamental concept and a complete guide to the prac- tical implementation of Database Management Systems. Concepts includes SQL, PL/SQL. These concepts include aspects of Database design, Data- base Languages, and Database System implementation. The entire book is divided into five units to ensure the smooth flow of the subject. The extra methodology makes it very useful for students as well as teachers.

  15. Web Technologies And Databases

    OpenAIRE

    Irina-Nicoleta Odoraba

    2011-01-01

    The database means a collection of many types of occurrences of logical records containing relationships between records and data elementary aggregates. Management System database (DBMS) - a set of programs for creating and operation of a database. Theoretically, any relational DBMS can be used to store data needed by a Web server. Basically, it was observed that the simple DBMS such as Fox Pro or Access is not suitable for Web sites that are used intensively. For large-scale Web applications...

  16. Database Application Schema Forensics

    OpenAIRE

    Hector Quintus Beyers; Olivier, Martin S; Hancke, Gerhard P.

    2014-01-01

    The application schema layer of a Database Management System (DBMS) can be modified to deliver results that may warrant a forensic investigation. Table structures can be corrupted by changing the metadata of a database or operators of the database can be altered to deliver incorrect results when used in queries. This paper will discuss categories of possibilities that exist to alter the application schema with some practical examples. Two forensic environments are introduced where a forensic ...

  17. Categorical Database Generalization

    Institute of Scientific and Technical Information of China (English)

    LIU Yaolin; Martin Molenaar; AI Tinghua; LIU Yanfang

    2003-01-01

    This paper focuses on the issues of categorical database gen-eralization and emphasizes the roles ofsupporting data model, integrated datamodel, spatial analysis and semanticanalysis in database generalization.The framework contents of categoricaldatabase generalization transformationare defined. This paper presents an in-tegrated spatial supporting data struc-ture, a semantic supporting model andsimilarity model for the categorical da-tabase generalization. The concept oftransformation unit is proposed in generalization.

  18. Fingerprint databases for theorems

    OpenAIRE

    Billey, Sara C.; Tenner, Bridget E.

    2013-01-01

    We discuss the advantages of searchable, collaborative, language-independent databases of mathematical results, indexed by "fingerprints" of small and canonical data. Our motivating example is Neil Sloane's massively influential On-Line Encyclopedia of Integer Sequences. We hope to encourage the greater mathematical community to search for the appropriate fingerprints within each discipline, and to compile fingerprint databases of results wherever possible. The benefits of these databases are...

  19. Searching Databases with Keywords

    Institute of Scientific and Technical Information of China (English)

    Shan Wang; Kun-Long Zhang

    2005-01-01

    Traditionally, SQL query language is used to search the data in databases. However, it is inappropriate for end-users, since it is complex and hard to learn. It is the need of end-user, searching in databases with keywords, like in web search engines. This paper presents a survey of work on keyword search in databases. It also includes a brief introduction to the SEEKER system which has been developed.

  20. Brain Tumor Database, a free relational database for collection and analysis of brain tumor patient information.

    Science.gov (United States)

    Bergamino, Maurizio; Hamilton, David J; Castelletti, Lara; Barletta, Laura; Castellan, Lucio

    2015-03-01

    In this study, we describe the development and utilization of a relational database designed to manage the clinical and radiological data of patients with brain tumors. The Brain Tumor Database was implemented using MySQL v.5.0, while the graphical user interface was created using PHP and HTML, thus making it easily accessible through a web browser. This web-based approach allows for multiple institutions to potentially access the database. The BT Database can record brain tumor patient information (e.g. clinical features, anatomical attributes, and radiological characteristics) and be used for clinical and research purposes. Analytic tools to automatically generate statistics and different plots are provided. The BT Database is a free and powerful user-friendly tool with a wide range of possible clinical and research applications in neurology and neurosurgery. The BT Database graphical user interface source code and manual are freely available at http://tumorsdatabase.altervista.org.