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Sample records for acidos grasos omega

  1. Efectos y controversias de los ácidos grasos omega-3: effects and controversies Omega-3 fatty acids

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    Fernando Manzur

    Full Text Available Gracias al descubrimieno del mecanismo de acción de los ácidos grasos omega-3 para disminuir las arritmias ventriculares, éstos han vuelto a cobrar importancia por su efecto cardio-protector. La ingestión de ácidos grasos omega-3 disminuye el riesgo de trombosis y accidentes cerebro-vasculares al disminuir los lípidos sanguíneos, mejorando en esta forma la función endotelial. Sin embargo, algunos estudios epidemiológicos no han encontrado una relación directa a este respecto y además hay controversia respecto a las dosis necesarias para lograr este efecto cardio-protector. Hay estudios que reportan que el contenido de metil-mercurio en peces afecta la disposición de los ácidos grasos omega-3. En el Caribe colombiano se ha encontrado contaminación de peces con metil-mercurio.Thanks to the discovery of omega-3 fatty acids’ mechanism of action, these have regained importance due to its cardio-protective effect. The ingestion of omega-3 fatty acids diminishes the risk of thrombosis and cerebro-vascular accidents by lowering serum lipids and improving endothelial function. Nevertheless, some epidemiological studies have not found a direct relationship with them and there is controversy with regard to the doses needed in order to achieve this cardio-protective effect. There are studies reporting that the methyl-mercury content in fish affects omega-3 fatty acids’ disposal. In the Colombian Caribbean region, fish contamination with methyl-mercury has been found.

  2. ENRIQUECIMIENTO DE HUEVOS CON ÁCIDOS GRASOS OMEGA-3 MEDIANTE LA SUPLEMENTACIÓN CON SEMILLA DE LINO (Linum usitatissimum EN LA DIETA

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    Gonzalo Díaz

    2009-04-01

    Full Text Available Objetivo. Enriquecer los huevos de gallina con ácidos grasos omega-3 (n-3 mediante la inclusión de semillas de lino en la dieta. Materiales y métodos. La dieta de las aves fue formulada con niveles de 0 (L0, 10 (L10, 15 (L15 y 20% (L20 de linaza. Se determinó la composición de ácidos grasos por cromatografía de gases y se evaluó la producción y calidad del huevo. Resultados. El porcentaje de producción de huevo fue superior en los grupos L0 y L15 (p<0.05 con 93,0 y 91,5% de producción comparada con 86,0 % en los grupos L10 y L20. La mejor conversión de alimento se presentó también en los grupos L0 y L15. Con la inclusión de semilla de lino, se incrementó el contenido de ácidos grasos n-3 desde 3,0 % en el grupo L0 hasta 12,6 % en el grupo L20, siendo los ácidos grasos n-3 á-linolénico (C18:3, n-3 y docosahexahenóico (DHA, C22:6, n-3 los hallados en mayor concentración. Con la inclusión de linaza en la dieta de las gallinas ponedoras se redujo el contenido de acido linoleico (C18:2n-6, lo cual resultó en una disminución en la relación n-6: n-3. Conclusiones. Con base en la evaluación económica se concluye que es posible enriquecer la yema de huevo de gallina hasta con un 10,1 % de ácidos grasos n-3 mediante la inclusión de un 15 % de linaza en la dieta de las gallinas, sin embargo, esto representó un sobrecosto de producción del 12%.

  3. Contenidos de isomeros trans de los acidos grasos en productos carnicos. (III) Tejido adiposo y grasa intramuscular de vacuno

    OpenAIRE

    Lluch, M. C.; Roca de Vinyals, M.; Parcerisa Egea, Javier; Guardiola Ibarz, Francesc; Codony Salcedo, Rafael; Rafecas Martínez, Magdalena; Boatella Riera, Josep

    1993-01-01

    Se presentan los resultados obtenidos para la determinación de ácidos grasos en una serie de muestras de tejidos subcutáneo y muscular, procedentes de canales de vacuno, por aplicación de la cromatografía en fase gaseosa, para los que se obtuvieron unos valores medios de 58.7% de ácidos saturados, 39.1 % de monoinsaturados y 2.7% de polinsaturados, en el tejido adiposo, y de 44.7% de saturados, 46.1% de monoinsaturados y 9.4% de polinsaturados, en el tejido muscular. Los contenidos de ácidos ...

  4. Revisión de los niveles de acidos grasos trans encontrados en distintos tipos de alimentos

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    Vicario, I. M.

    2007-03-01

    Full Text Available In this paper a comprehensive review of trans-fatty acid levels reported in different types of food products is offered. The lowest levels are found in some types of bread (0,1% while the highest levels (up to 40% are found in fried potatoes. Some foods like shortenings, cakes and pastries may have up to 30% of these fatty acids. In milk and dairy products the reported levels are between 1.50% and 5.20%, in meat and derived products between 0.20% and 21,30%; in chocolates from 0% to 15, 70%. The greatest variability is found in margarines, where a variety has been reported from “trans-free products” to products containing up to 34. 30%. In relation to the trans-fatty acid profile, 18:1t is the most abundant fatty acid found in the majority of foods, followed by C18:2t, C18:3t, C18:1t y C14:1t. Due to the negative health effects of these fatty acids, there is a trend to reduce their levels in food products and to include them in the nutritional label of food packaging.En este trabajo se realiza una exhaustiva revisión bibliográfica de los contenidos en grasos trans en alimentos de distinto origen. Los niveles más bajos se encuentran en algunos tipos de pan (0,10%, y los más elevados (hasta 40%, en algunas muestras de patatas fritas. Alimentos tales como shortenings, algunos tipos de galletas y bollería contienen hasta el 30% de dichos ácidos grasos. En las leches y derivados se encuentran cantidades entre 1,50% y 5,20%; en carnes y derivados entre 0,20% y 21,30%; en chocolates desde cantidades nulas hasta 15,70%. La mayor variabilidad se registra en margarinas, entre las que se encuentran desde las “libres de trans”, hasta algunas con 34,30% de estos ácidos grasos. En cuanto a los distintos isómeros, el mayoritario es el C18:1t seguido del C18:2t, C18:3t, C18:1t y C14:1t. Debido a los efectos desfavorables que presentan sobre la salud se observa en los últimos años una tendencia a reducir este tipo de ácidos grasos en algunos

  5. Efectos del consumo de ácidos grasos omega-3 sobre la salud cardiovascular, cerebral y diversas enfermedades del sistema nervioso central

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    Elba Cubero Castillo

    2016-10-01

    Full Text Available Se realizó una revisión de los trabajos publicados sobre los efectos del consumo de ácidos grasos omega-3, (ácido alfa-linolénico (AAL, ácido docosahexaenoico (ADH y ácido eicosapentaenoico (AEP sobre la salud de las personas en diferentes periodos de la vida. Se discuten los beneficios obtenidos en el ámbito de la salud sobre los sistemas circulatorio y nervioso. Se mencionan diferentes fuentes alimenticias de origen animal y vegetal en las que se encuentran disponibles los ácidos grasos omega-3, especialmente ADH y AEP. Se encontró que muchos de los tratamientos actuales de trastornos del sistema nervioso y de problemas cognitivos involucran el consumo de ácidos grasos omega-3, dando resultados positivos en diversos cuadros clínicos.

  6. Inflamación celular en pacientes sometidos a cirugía electiva tratados con carbohidratos de baja carga glicémica, ácidos grasos omega 3 y antioxidantes

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    Lucrecia Arceo-Giorgana

    2016-03-01

    Full Text Available Antecedentes y Objetivos. La creciente complejidad de la Especialidad de Cirugía Plástica, ha inducido a su ramificación en varias subespecialidades. Una de las limitantes de la Cirugía Plástica ha sido la obesidad, enfermedad que conlleva complicaciones, aumenta el riesgo de inconvenientes y hace insuficiente el resultado proyectado para la estética y la función. El objetivo del presente trabajo es mostrar la importancia de la evaluación de la inflamación celular en la preparación de pacientes sometidos a cirugía electiva, previamente tratados con dieta con carbohidratos de baja carga glicémica, ácidos grasos omega 3 y 6 y antioxidantes. Material y Método. Realizamos un estudio longitudinal prospectivo cuasi-experimental no aleatorio de 23 pacientes que solicitaron intervenciones de Cirugía Plástica y aceptaron entrar en el protocolo de diagnóstico y tratamiento de inflamación celular. Primero realizamos el cuestionario de Reporte de Inflamación Celular "RIS" y tomamos a los pacientes pruebas de inflamación celular y de ácido eicosapentaenóico (EPA, ácido decosaexaenóico (DHA, acido araquidónico (AA y ácido dihomogamalinoléico (DGLA al ingreso y antes de la cirugía. Analizamos los datos con estadística descriptiva y comparamos los rangos con la prueba McNemar y de hipótesis t de student, del sistema SPSS. Resultados. Tras aplicar el RIS a los 23 pacientes antes de la preparación con dieta y tras un periodo de 1 a 3 meses, evaluamos las respuestas de cada uno de los cuestionarios a través de las pruebas no paramétricas, encontrando diferencia significativa en los 14 items. Se mejoró considerablemente a la alza el EPA; el DHA y el AA sin cambios significativos; y el DGLA disminuyó considerablemente. Con t de student encontramos variación significativa en los fosfolípidos del plasma y no hubo diferencia significativa entre los DHA y AA. Conclusiones. Demostramos así la efectividad de la dieta de los omegas

  7. Aprovechamiento de residuos pesqueros para la obtención de ácidos grasos (omega 3) en el procesamiento de productos alimenticios

    OpenAIRE

    Robalino Jaime, Johanna Jessenia

    2008-01-01

    Ecuador cuenta con una significativa riqueza pesquera que comprende gran variedad de especies de alto valor comercial que permite importantes niveles de procesamiento y exportación de productos pesqueros entre los que se pueden citar la harina y el aceite de pescado. El aceite de pescado es la principal fuente de ácidos grasos omega 3, ácido eicosapentaenoico (EPA) y ácido docosahexaenoico (DHA) siendo las especies piscícolas ecuatorianas muy ricas en estos componentes. El objetivo principal ...

  8. PROCESO ENZIMATICO PARA LA PRODUCCION DE METIL ESTERES DE ACIDOS GRASOS UTILIZANDO ACEITES RESIDUALES DE FRITURA EN MEZCLA CON ACEITE DE RAPS COMO MATERIA PRIMA

    OpenAIRE

    AZOCAR ULLOA; LAURA HAYDEE

    2010-01-01

    Los procesos catalizados por lipasas han sido ampliamente investigados como alternativa para la producción de metil ésteres de ácidos grasos (fatty acid methyl ester, FAME) o biodiesel. El interés en este proceso radica en que a diferencia de los procesos convencionales catalizados con sales alcalinas, los procesos catalizados con lipasas permiten el uso de materias primas alternativas y de menor costo, tales como el aceite residual de fritura (waste frying oil, WFO). Pese a los l...

  9. Efecto de la adicion de extracto de vino tinto en la conservacion de hamburguesas de cordero enriquecidas en acidos grasos omega-3

    National Research Council Canada - National Science Library

    Muino, I; Apeleo, E; Perez-Santaescolastica, C; Diaz, M.T; Perez, C; De la Fuente, J; Lopez, O; Caneque, V; Rivas-Canedo, A; Bermejo, R; Lauzurica, S

    2013-01-01

    .... El objetivo de este estudio fue evaluar el efecto de la adicion de extracto de vino (EV) en la estabilidad oxidativa de hamburguesas de cordero, estudiando la formacion de metamioglobina (MetMb...

  10. Influencia de los ácidos grasos poliinsaturados omega-3 y omega-6 de la dieta y de sus metabolitos en la respuesta inmune de tipo alérgico

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    Deivis Javier Villanueva-Pájaro

    2015-04-01

    Full Text Available Las tasas de prevalencia para las enfermedades alérgicas han incrementado en gran medida en los últimos cincuenta años, tanto en países desarrollados como en vías de desarrollo. En estos últimos, dicho incremento está representado principalmente por la población de niños y adolescentes; un evento que a su vez se concibe como un problema relevante de salud pública mundial. Varios factores han sido propuestos para explicar las causas de esta problemática, entre los que destaca la hipótesis de la dieta, señalando que componentes específicos de la alimentación y cambios en los patrones del mismo propiciarían el desarrollo de las alergias e influirían en el incremento de su prevalencia. En apoyo de lo anterior, la hipótesis de las grasas expone que paralelo al aumento de las alergias a nivel global, ha existido también un consumo excesivo de alimentos con alto contenido de ácidos grasos omega-6 y bajos en omega-3, principalmente en dietas occidentales y como resultado de intervenciones en prevención del riesgo cardiovascular, lo que en conjunto pudiera explicar parte de este fenómeno mundial. La evidencia a nivel epidemiológico y experimental muestra que ambas series de lípidos y varios de sus metabolitos ejercen un importante papel modulador en la patología alérgica, aspectos que serán abordados en la presente revisión temática.

  11. Análisis bibliométrico y temático de la producción científica sobre ácidos grasos omega-3 indizada en las bases de datos internacionales sobre ciencias de la salud Bibliometric and thematic analysis of the scientific literature about omega-3 fatty acids indexed in international databases on health sciences

    OpenAIRE

    J. Sanz-Valero; Á. Gil; Wanden-Berghe, C.; E. Martínez de Victoria

    2012-01-01

    Objetivo: Evaluar mediante el análisis bibliométrico y temático la producción científica sobre ácidos grasos omega-3 indizada en las bases de datos internacionales sobre ciencias de la salud, estableciendo a su vez una base comparativa para análisis futuros. Método: Las búsquedas se realizaron, con el Descriptor (MeSH, como Major Topic) "Fatty Acids, Omega-3" desde la primera fecha disponible hasta el 31 de diciembre de 2010. Bases de datos consultadas: MEDLINE (via PubMed), EMBASE, ISI Web o...

  12. DESARROLLO DE ESTRATEGIAS PARA EL AUMENTO DEL RENDIMIENTO DE CONVERSION A ALQUIL ESTERES DE ACIDOS GRASOS (BIODIESEL) MEDIANTE EL USO DE CLEAS DE LIPASA COMO CATALIZADOR DE LA REACCION DE TRANSESTERIFICACION A PARTIR DE ACEITE DE RAPS CANOLA

    OpenAIRE

    CABALLERO VALDES, EDUARDO

    2011-01-01

    Debido al inminente agotamiento de las reservas de petróleo se ha desarrollado una gran cantidad de proyectos destinados a la generación de biocombustibles como energías alternativas renovables, dentro de los cuales se encuentra el biodiesel (alquil ésteres de ácidos grasos), el que se produce principalmente mediante la transesterificación de triglicéridos con un alcohol en presencia de un catalizador. Se ha planteado como hipótesis que la máxima conversión de alquil ésteres de ácidos gras...

  13. Efectos cardiovasculares de los ácidos grasos Omega-3 y alternativas para incrementar su ingesta Cardiovascular effects of omega-3-fatty acids and alternatives to increase their intake

    OpenAIRE

    Carrero, J.J.; E. Martín-Bautista; L. Baró; J. Fonollá; Jiménez, J.; Boza, J.J; López-Huertas, E

    2005-01-01

    Las enfermedades cardiovasculares son la principal causa de mortalidad en Europa, Estados Unidos y gran parte de Asia. Existen varios factores de riesgo asociados a las enfermedades cardiovasculares, entre ellos están el colesterol total, la homocisteína y los triglicéridos elevados, la hipertensión, la diabetes y niveles reducidos de colesterol HDL. Muchos de estos factores de riesgo son influenciables por la dieta. A pesar de la gran cantidad de alimentos enriquecidos en ácidos grasos n-3 d...

  14. Estabilidad oxidativa de huevos enriquecidos con ácidos grasos poliinsaturados omega 3, frente a antioxidantes naturales Estabilidade oxidativa de ovos enriquecidos com ácidos graxos poliinsaturados ômega 3, frente a antioxidantes naturais

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    María Elena Bernal Gómez

    2003-12-01

    Full Text Available Fueron alimentadas 192 gallinas ponedoras de 22 semanas de edad, de linaje comercial Babcock, durante 30 días con dietas de 0 (cero y 12,7% de semilla de linaza molida que corresponde a 0 y 5% de aceite de linaza, respectivamente. Fueron definidos 8 tratamientos: 4 grupos con 12,7% de semilla de linaza (control/sin antioxidante; BHA+BHT, 100+100 ppm; orégano, 200 ppm; romero, 200 ppm y 4 grupos sin semilla de linaza, pero utilizando los mismos antioxidantes. Este estudio fue realizado con el objetivo de verificar la eficacia del uso de antioxidantes naturales provenientes del orégano y del romero en la protección contra el deterioro oxidativo de la fracción lipídica de las yemas de los huevos enriquecidos con ácidos grasos poliinsaturados omega 3 (PUFA É-3. El grado de oxidación lipídica fue determinado a través de la prueba TBARS (substancias reactivas con ácido tiobarbitúrico. Según los resultados obtenidos, fue verificada diferencia significativa en la reducción del grado de oxidación lipídica de las yemas de huevo en todos los tratamientos con antioxidantes, cuando se compara con el control. Por lo tanto, los extratos de los condimentos, romero y orégano, pueden ser utilizados satisfactoriamente para obtener huevos enriquecidos con PUFA É-3, mejorando la estabilidad lipídica.Foram alimentadas 192 galinhas poedeiras de 22 semanas de idade da linhagem comercial Babcock, durante 30 dias com dietas constituídas de 0 (zero e 12,7% de semente de linhaça moída correspondente a 0 e 5% de óleo de linhaça, respectivamente. Foram definidos 8 tratamentos: 4 grupos com 5% de óleo de linhaça (controle/sem antioxidante; BHA+BHT, 100+100 ppm; orégano, 200 ppm; alecrim, 200 ppm e 4 grupos sem óleo de linhaça, mas utilizando os mesmos antioxidantes. Este estudo foi realizado com o objetivo de verificar a eficácia do uso de antioxidantes naturais provenientes do orégano e do alecrim, na proteção contra a deteriora

  15. Síndrome de distrés respiratorio agudo (SDRA). El papel de los eicosanoides y su modulación mediante una nutrición parenteral enriquecida con ácidos grasos omega-3

    OpenAIRE

    Sabater Riera, Joan

    2014-01-01

    Un primer objetivo de la tesis ha sido estudiar el papel de los eicosanoides en el desarrollo del síndrome de distrés respiratorio agudo (SDRA) mediante el estudio de sus concentraciones. Otro objetivo ha sido analizar si el aporte de una emulsión lipídica administrada por vía parenteral enriquecida con ácidos grasos poliinsaturados de la serie 3 (AGPI n-3) en forma de aceite de pescado y bajo aporte de ácido linoleico (AGPI n-6) puede regular la síntesis de eicosanoides en pacientes con SDRA...

  16. Complejos de Albúmina con Ácidos Grasos CIS-monoinsaturados Omega-9 para el tratamiento del Dolor Neuropático asociado a la Lesión Medular

    OpenAIRE

    Ávila Martín, Gerardo

    2016-01-01

    Tesis Doctoral leída en la Universidad Rey Juan Carlos de Madrid en 2016. Director de la Tesis: Julian Taylor La disfunción sensitivomotora tras una lesión medular (LM) a menudo se caracteriza por síntomas discapacitantes tales como el dolor neuropático y la parálisis motora, que demandan el desarrollo de tratamientos novedosos. Recientemente, se ha demostrado el papel de los ácidos grasos y sus derivados como moléculas neuromoduladoras de la nocicepción y la actividad motora ...

  17. Perfil de ácidos grasos de aceite de Sacha inchi (Plukenetia volubilis) en comparación con otros aceites vírgenes comestibles

    OpenAIRE

    Ramos Escudero, Fernando; Ponce Dayer, Lady; Barnett Mendoza, Edy; Celi Saavedra, Luis; Ramos Escudero, Mónica

    2016-01-01

    El consumo de ácidos grasos omega-3 ya sea de origen animal o vegetal puede proteger de las enfermedades cardiovasculares. El aceite de Sacha Inchi se considera como un cultivo promisorio por su aporte saludable, además desde el punto de vista de ácidos grasos aún sigue siendo mayoritario en comparación con otros aceites vírgenes. El contenido de ácidos grasos saturados se encuentra alrededor de 7.04%, mientras que el contenido de ácidos grasos poliinsaturados so...

  18. Suplementação de ácidos graxos ômega 3 em atletas de competição: impacto nos mediadores bioquímicos relacionados com o metabolismo lipídico Adición de ácidos grasos omega 3 en atletas de competición: impacto en los mediadores bioquímicos relacionados con el metabolismo lipídico Omega 3 fatty acids-supplementation to competition athletes: impact on the biochemical indicators related to the lipid metabolism

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    Priscila de Mattos Machado Andrade

    2006-12-01

    Full Text Available OBJETIVO: Avaliar o efeito da suplementação dos ácidos graxos ômega 3 em atletas de natação sobre indicadores bioquímicos. MÉTODOS: Nadadores de elite (n = 14 do sexo masculino foram avaliados em estudo randomizado, controlado por placebo pelo período de seis semanas (45 dias. O grupo placebo (GP recebeu óleo mineral (n = 6 e o grupo suplementado (n = 8, óleo de peixe (GOP contendo, no total, 950mg de ácido eicosapentaenóico e 500mg de ácido docosapentaenóico. Amostras de sangue foram coletadas imediatamente antes (T0, aos 15 (T15, aos 30 (T30 e aos 45 (T45 dias de suplementação para análise da composição dos ácidos graxos por cromatografia gasosa e para quantificação das lipoproteínas plasmáticas através de kits comerciais específicos. RESULTADOS: Os resultados revelaram um desajuste na dieta dos atletas considerando a ingestão g/kg de massa corporal dos macronutrientes. A análise do questionário de freqüência de consumo mostrou que os atletas não ingeriram regularmente fontes alimentares de ômega 3 e que o consumo de peixes, em 85% da amostra, era inferior ou igual a uma vez na semana. O perfil de ácidos graxos plasmáticos evidenciou aumento dos ácidos graxos poliinsaturados ômega 3 (P 0,05. CONCLUSÃO: A suplementação de ácidos graxos N-3 em atletas nadadores altera os indicadores bioquímicos do metabolismo lipídico, influenciando na redução das lipoproteínas plasmáticas, ricas em colesterol e na prevenção de doenças cardiovasculares.OBJETIVO: Evaluar el efecto suplementar de los ácidos grasos omega 3 en atletas de natación sobre indicadores bioquímicos. MÉTODOS: Nadadores de elite (n = 14 del sexo masculino fueron evaluados en estudio aleatorio, controlado por placebo por un período de 6 semanas (45 días. El grupo placebo (GP recibió aceite mineral (n = 6 y el grupo suplementado (n = 8 recibió aceite de pescado (GOP conteniendo en total 950 mg de ácido eicosapentaenóico y 500 mg de

  19. Omega 3 fatty acids supplementation has an ameliorative effect in experimental ulcerative colitis despite increased colonic neutrophil infiltration Los suplementos de ácidos grasos omega 3 tienen efectos beneficiosos en colitis ulcerosa a pesar del aumento de la infiltracción por neutrófilos del colon

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    Ioannis Varnalidis

    2011-10-01

    Full Text Available Purpose: omega 3 polyunsaturated fatty acids have anti-inflammatory properties and can be beneficial in the treatment of inflammatory diseases, such as ulcerative colitis. Dextran sodium sulphate (DSS colitis in rats appears to mimic nearly all of the morphological characteristics and lesion distributions of ulcerative colitis. The purpose of the current study was to investigate the efficacy of omega 3 fatty acids in the treatment of experimental ulcerative colitis. Methods: thirty-six Wistar rats were randomly assigned to group A or group B receiving 5% dextran sulfate sodium (DSS in their drinking water for eight days. For the next eight days post-DSS, group A animals received tap-water, and group B animals were fed a nutritional solution containing high levels of omega 3 polyunsaturated fatty acids (ProSure®, Abbott Laboratories, Zwolle, Netherlands once per day, administrated with a orogastric feeding tube. Results: animals fed an omega 3 rich diet exhibited a statistically significant increase in hematocrit and hemoglobin levels, compared to animals drinking tap water, and a trend towards histopathological and clinical improvement, with the administration of omega 3 fatty acids ameliorating epithelial erosion by day 8 post-DSS, but no statistically significant difference was observed between group A and group B animals at 4 or 8 days post-DSS. Also, a statistically significant increase in neutrophil infiltration was observed, as depicted by myelohyperoxidase activity. Conclusion: our findings support a positive role of omega 3 polyunsaturated fatty acids supplementation in an experimental model of ulcerative colitis despite the increased colonic neutrophil infiltration. Further studies are needed in order to investigate the role of increased neutrophils in colonic mucosa.

  20. Efecto del proceso de elaboración de la conserva "desmenuzado de anchoveta" (Engraulis ringens) sobre los ácidos grasos poliinsaturados omaga3

    OpenAIRE

    Ordoñez, Lenny R.; Instituto Tecnológico de lta Producción del Perú, Lima-Perú Facultad de Farmacia y Bioquímica, Universidad Nacional Mayor de San Marcos (UNMSM). Lima, Perú; Hernánde, Eloisa M.; Facultad de Farmacia y Bioquímica, Universidad Nacional Mayor de San Marcos (UNMSM). Lima, Perú 3Instituto de Investigación en Química Biológica, Microbiología y Biotecnología “Marco Antonio Garrido Malo”, de la Facultad de Farmacia y Bioquímica. Universidad Nacional Mayor de San Marcos. Lima, Perú

    2015-01-01

    La anchoveta (Engraulis ringens) es uno de los principales recursos pesqueros explotados en el Perú. Es rica fuente de proteínas de alto valor biológico y de ácidos grasos poliinsaturados omega-3: ácido eicosapentaenoico (EPA) y ácido docosahexaenoico (DHA). El objetivo fue determinar el efecto del proceso de elaboración de la conserva de "desmenuzado de anchoveta", con énfasis sobre los ácidos grasos poliinsaturados omega-3 y el contenido real de estos en la conserva. Se elaboró siguiendo la...

  1. Higado graso no alcoholico: ?un componente inflamatorio del sindrome metabolico?

    National Research Council Canada - National Science Library

    Almarza, Johan

    2010-01-01

    Objetivo: integrar los componentes que relacionan la insulinorresistencia en el desarrollo de higado graso no alcoholico y los mecanismos moleculares implicados en la fisiopatologia, los metodos diagnosticos...

  2. Acido urico, aterosclerosis y calcificaciones vasculares en enfermedad renal cronica

    National Research Council Canada - National Science Library

    D'Marco, Luis; Garcia, Irene; Vega, Claudia

    2012-01-01

    ...). Las complicaciones vasculares son principalmente secundarias a calcificaciones y ateroesclerosis. En los ultimos anos se ha renovado el interes por la asociacion entre niveles de acido urico y riesgo cardiovascular...

  3. Physicochemical properties of technetium acido clusters

    Science.gov (United States)

    Kryutchkov, Sergei V.

    1998-10-01

    The review is concerned with the electronic and molecular structure and physicochemical properties of all types of technetium clusters with acido ligands described to date. As a typical cluster-forming metal, technetium possesses a number of specific, anomalous cluster-forming properties that can be interpreted in terms of greater capability of outer diffuse 5s(5p) AOs to participate in the formation of additional M-M bonds in technetium acido clusters as compared to analogous clusters of other transition d-elements. Theoretical interpretation of the electronic and molecular structure and properties of technetium clusters has been confirmed by experimental data (X-ray analysis, magnetochemistry, and EPR, optical, X-ray photoelectron and X-ray emission spectroscopy). The experimentally observed increased stability of technetium clusters with odd numbers of 'metallic' electrons and a decrease in the effective charge on Tc atoms upon formation of the M-M bonds are discussed. Recently found 'anomalous' properties of technetium and rhenium compounds with ferrocenium cations (in particular, unusual low-temperature electron emission on X-ray irradiation) are also considered. The bibliography includes 101 references.

  4. Physicochemical properties of technetium acido clusters

    Energy Technology Data Exchange (ETDEWEB)

    Kryutchkov, Sergei V [Institute of Physical Chemistry, Russian Academy of Sciences, Moscow (Russian Federation)

    1998-10-31

    The review is concerned with the electronic and molecular structure and physicochemical properties of all types of technetium clusters with acido ligands described to date. As a typical cluster-forming metal, technetium possesses a number of specific, anomalous cluster-forming properties that can be interpreted in terms of greater capability of outer diffuse 5s(5p) AOs to participate in the formation of additional M-M bonds in technetium acido clusters as compared to analogous clusters of other transition d-elements. Theoretical interpretation of the electronic and molecular structure and properties of technetium clusters has been confirmed by experimental data (X-ray analysis, magnetochemistry, and EPR, optical, X-ray photoelectron and X-ray emission spectroscopy). The experimentally observed increased stability of technetium clusters with odd numbers of 'metallic' electrons and a decrease in the effective charge on Tc atoms upon formation of the M-M bonds are discussed. Recently found 'anomalous' properties of technetium and rhenium compounds with ferrocenium cations (in particular, unusual low-temperature electron emission on X-ray irradiation) are also considered. The bibliography includes 101 references.

  5. Respuesta hipofisaria y ovulatoria de conejas nuliparas alimentadas con dietas suple mentadas con acidos grasos poliinsaturados n-3

    National Research Council Canada - National Science Library

    Pascual, J.I; Millan, P; de la Riva, S; Garcia-Garcia, R.M; Arias-Alvarez, M; Rodriguez, M; Lorenzo, P.L; Rebollar, P.G

    2013-01-01

    Veinte conejas nuliparas se alimentaron ad libitum desde las 10 a las 16 semanas de edad con dos piensos isofibrosos, isoenergeticos e isoproteicos suplementados con dos fuentes de grasa diferentes: 0,75...

  6. Fertilidad, desarrollo embrionario y prolificidad de conejas nuliparas alimentadas con piensos enriquecidos en acidos grasos poliinsaturados n-3

    National Research Council Canada - National Science Library

    Pascual, J.I; Gonzalez-Bulnes, A; Arias-Alvarez, M; Garcia-Garcia, R.M; Masdeu, M; Formoso-Lafferty, N; Rodriguez, M; Ciacci, A; Lorenzo, P.L; Rebollar, P.G

    2013-01-01

    ... cuando se utiliza en medios de maduracion in vitro e incrementa su viabilidad (vacuno: Marei et al., 2009; ovino: Hughes et al., 2010). Estos nutrientes son necesarios en numerosos procesos fisiologicos como el crecimiento, la reproduccion, la vision y el desarrollo cerebral (Gurr et al., 2002). En recientes estudios hemos comprobado que las c...

  7. Fertilidad, desarrollo embrionario y prolificidad de conejas nuliparas alimentadas con piensos enriquecidos en acidos grasos poliinsaturados n-3

    National Research Council Canada - National Science Library

    Pascual, J.I; Gonzalez-Bulnes, A; Arias-Alvarez, M; Garcia-Garcia, R.M; Masdeu, M; Formoso-Lafferty, N; Rodriguez, M; Ciacci, A; Lorenzo, P.L; Rebollar, P.G

    2013-01-01

    Un total de 105 conejas nuliparas se alimentaron ad libitum un mes antes y durante su primera gestacion con dos piensos isofibrosos, isoenergeticos e isoproteicos suplementados con dos fuentes de grasa diferentes: 0,75...

  8. Monocapas de ácidos grasos. I. Ácido esteárico sobre disoluciones acuosas de etanol

    Directory of Open Access Journals (Sweden)

    Rodríguez Patino, J. M.

    1991-04-01

    Full Text Available The structure and stability of fatty acid monolayers spread on aqueous solutions with ethanol has been studied. The experiments were carried out isothermically using a commercial Langmuir balance (Lauda. Monolayers exhibit solid or condensed liquid structure depending of the ethanol concentration in the subphase. Temperature has not a significant influence on the monolayer. Structure there is a loss of stearic acid film through solution into the adjacent subphase. This loss is increased with the temperature and ethanol concentration in the subphase.

    Monocapas de ácidos grasos. I. Acido esteárico sobre disoluciones acuosas de etanol. Se ha estudiado la estructura y estabilidad de monocapas de ácido esteárico esparcidas sobre disoluciones acuosas que contienen etanol. Las experiencias se han realizado en una balanza de superficie comercial tipo Langmuir y se ha operado en condiciones isotérmicas. Las monocapas presentan estructuras de tipo sólida o de líquido condensado en función de la concentración de etanol en la subfase. La estructura que adopta la monocapa es prácticamente independiente de la temperatura. La pérdida de moléculas de ácido esteárico de la monocapa por disolución en la subfase se incrementa a los valores más elevados de temperatura y de concentración de etanol.

  9. Ácidos grasos, alteraciones e importancia nutricional

    OpenAIRE

    Losada Álvarez, Laura

    2017-01-01

    Los ácidos grasos son los componentes más frecuentes en los lípidos presentes en los seres vivos. El estudio de los ácidos grasos se ha convertido en un campo de investigación de creciente importancia debido a su repercusión en los lípidos que los contienen, y en las numerosas funciones biológicas que estos desempeñan. Los ácidos grasos no solo intervienen como almacenes de reserva energética, sino también como componentes estructurales de la célula, moléculas señalizadoras, ...

  10. ANÁLISIS PROXIMAL, PERFIL DE ÁCIDOS GRASOS DE LAS VÍSCERAS DEL CUY (Cavia porcellus Y SU USO POTENCIAL EN ALIMENTACIÓN ANIMAL

    Directory of Open Access Journals (Sweden)

    A. S. Parra

    2016-01-01

    Full Text Available Con el fin de evaluar el valor nutritivo de materias primas no convencionales en la elaboración de concentrado animal, de bajo coste y que no compitan con la alimentación del hombre, en la presente investigación se analizó el contenido nutricional de las vísceras abdominales de cuy (Cavia porcellus y de su harina, usando análisis proximal y perfil de ácidos grasos mediante cromatografía de gases. Se compararon estos resultados con materias primas convencionales como la harina de pescado y con vísceras de diversos animales. Los resultados obtenidos indican que la harina de vísceras de cuy puede competir con harinas de diversas procedencias dadas sus cualidades nutricionales (58% proteína, 28% grasa, 4% cenizas; además, el alto contenido de grasa en las vísceras frescas (55% base seca está constituido principalmente ácidos grasos poliinsaturados tipo omega 3, 6 y 9, siendo relevante el contenido de ácido linolénico, ácidos grasos que en la dieta de los animales son escasos y de alto costo. Es posible concluir que los componentes nutricionales de las vísceras de cuy la convierten en una materia prima promisoria en alimentación animal, estimulando así el aprovechamiento de estos residuos.

  11. Contenido de ácidos grasos en carne de cuy

    Directory of Open Access Journals (Sweden)

    César Iván Flores-Mancheno

    2015-07-01

    Full Text Available El objetivo del estudio fue determinar la composición de ácidos grasos en carne de cuy. El trabajo se desarrolló en la ciudad de Riobamba (Ecuador, y las líneas de cuyes utilizadas fueron tres: Criolla, Andina y Peruana mejorada. Se realizó análisis de varianza para las diferencias, comparación de medias según Duncan (p < 0.05. El contenido total de ácidos grasos saturados en la carne de este roedor no registró diferencias estadísticas entre las líneas estudiadas, ya que presentaron valores de 37,11, 37,01 y 36,71%, para cuyes Criollo, Andino y Peruano mejorado, respectivamente; igualmente, el contenido de ácidos monoinsaturados tampoco registró diferencias estadísticas entre las tres líneas, pues se reportaron niveles de 30,49, 29,26 y 31,44%, ni los niveles de ácidos grasos poliinsaturados, que fueron de 13,30, 11,04 y 14,22%.

  12. Purificação de acido clavulanico utilizando zeolitas.

    OpenAIRE

    Marcus Bruno Soares Forte

    2008-01-01

    Resumo: O presente trabalho teve como objetivo principal a separação e purificação de acido clavulanico a partir de caldo fermentado utilizando zeolitas. Foram utilizadas zeolita natural (ZN) e sintetica faujasita (13X), ambas modificadas por troca ionica com diferentes cations de compensação (Na+1, K+1, Ca+2, Ba+2, Mg+2, Sr+2). Atraves de estudos cineticos de adsorcao de AC, usando as diferentes zeolitas nas respectivas formas cationicas, selecionou-se a zeolita 13X-Na como a mais promissora...

  13. Evaluacion de las propiedades mecanicas de poliesteramidas derivadas de los acidos tartarico y succinico

    National Research Council Canada - National Science Library

    Perez-Rodriguez, Angel T; Fernandez-Santin, Jose M; Alla, Abdellilah; Munoz-Guerra, Sebastian

    2012-01-01

    ...% de ester, obtenidas a partir de los acidos tartarico y succinico. Las mismas constituyen polimeros que presentan potencial aplicacion en el sector biomedico por su posible utilizacion en intervenciones quirurgicas para hilos de sutura...

  14. Concentraciones de acido urico e hiperuricemia en pacientes con hipertension arterial sistemica

    National Research Council Canada - National Science Library

    Lopez-Rosado, Ivonne; Luz-Araujo, Hedy; Guerra-Velasquez, Mery; Reyna-Villasmil, Eduardo; Mejia Montilla, Jorly; Reyna-Villasmil, Nadia; Torres-Cepeda, Duly

    2009-01-01

    El objetivo de la investigacion fue relacionar las concentraciones de acido urico y la presencia de hiperuricemia con la presion arterial en pacientes con diagnostico de hipertension arterial sistemica...

  15. Seguimiento de la titulacion acido monoprotico debil--base fuerte con cromatografia de alta resolucion --HPLC

    National Research Council Canada - National Science Library

    Correa Maya, Carlos Arturo; Dario Arbelaez, Edgar

    2008-01-01

    Con este articulo se propone la cromatografia liquida de alta resolucion --High Performance Liquid Chromatography-- como alternativa para realizar el seguimiento a las titulaciones de acidos debiles con bases fuertes...

  16. Composicao de acidos graxos do oleo do mesocarpo e da semente de cultivares de abacate da regiao de Ribeirao Preto, SP

    National Research Council Canada - National Science Library

    Massafera, Gisele; Braga costa, Telma Maria; Dutra De Oliveira, Jose Eduardo

    2010-01-01

    ...) e apos a esterificacao as amostras foram injetadas em cromatografo a gas. No oleo do mesocarpo, o acido graxo que apresentou maior concentracao foi o acido oleico, com teores entre 31,77 e 50,30...

  17. Deficiencia de ácidos grasos esenciales en el feto y en el recién nacido pretérmino

    Directory of Open Access Journals (Sweden)

    Virginia Díaz-Argüelles Ramírez-Corría

    2001-03-01

    Full Text Available Se informa que los ácidos grasos poliinsaturados de cadena larga son esenciales en la nutrición del feto y el recién nacido (RN. Tanto la familia omega 3(omega-3 como la omega 6(omega-6, tienen 2 actividades biológicas importantes que son la integridad de las membranas celulares y la formación de prostaglandinas y tromboxanos. El cerebro fetal se desarrolla precozmente y el 60 % de su material estructural son los lípidos, por lo tanto existe una relación entre el estado nutricional de la madre y la acreción de nutrientes durante el embarazo. El 70 % del número total de neuronas se divide antes del nacimiento a término y los ácidos grasos esenciales desempeñan un papel determinante. La placenta tiene un transporte preferencial a finales del tercer trimestre, de ácido araquidónico (AA y docosahexaenoico (DHA, pues los mecanismos de desaturación y elongación son inmaduros en el RN a término. La deficiencia de ácidos grasos poliinsaturados de cadena larga en el RN pretérmino afecta fundamentalmente el desarrollo cerebral y de la retina a largo plazo y se manifiesta con trastornos hematológicos, dermatitis, hipotonía, entre otros, de forma precoz. Se exponen las recomendaciones de la FAO/OMS y de la ESPGAN en relación con el aporte dietético de ácidos grasos esenciales en las formulaciones de leches artificiales y las ventajas de la leche materna biológica para los RN de este grupo de peso.It is reported that the long chain polyunsaturated fatty acids are essential in the nutrition of the fetus and of the newborn infant. Both, the omega 3 family 3(W-3 and the omega 3(W-6 have 2 important biological activities, which are the integrity of the cellular membranes and the formation of prostaglandins and thromboxanes. The fetal brain develops early and 60 % of its structrural material are lipids, therefore, there is a relationship between the nutritional status of the mother and the decreasing of nutrients during pregnancy. 70 % of

  18. Omega documentation

    Energy Technology Data Exchange (ETDEWEB)

    Howerton, R.J.; Dye, R.E.; Giles, P.C.; Kimlinger, J.R.; Perkins, S.T.; Plechaty, E.F.

    1983-08-01

    OMEGA is a CRAY I computer program that controls nine codes used by LLNL Physical Data Group for: 1) updating the libraries of evaluated data maintained by the group (UPDATE); 2) calculating average values of energy deposited in secondary particles and residual nuclei (ENDEP); 3) checking the libraries for internal consistency, especially for energy conservation (GAMCHK); 4) producing listings, indexes and plots of the library data (UTILITY); 5) producing calculational constants such as group averaged cross sections and transfer matrices for diffusion and Sn transport codes (CLYDE); 6) producing and updating standard files of the calculational constants used by LLNL Sn and diffusion transport codes (NDFL); 7) producing calculational constants for Monte Carlo transport codes that use group-averaged cross sections and continuous energy for particles (CTART); 8) producing and updating standard files used by the LLNL Monte Carlo transport codes (TRTL); and 9) producing standard files used by the LANL pointwise Monte Carlo transport code MCNP (MCPOINT). The first four of these functions and codes deal with the libraries of evaluated data and the last five with various aspects of producing calculational constants for use by transport codes. In 1970 a series, called PD memos, of internal and informal memoranda was begun. These were intended to be circulated among the group for comment and then to provide documentation for later reference whenever questions arose about the subject matter of the memos. They have served this purpose and now will be drawn upon as source material for this more comprehensive report that deals with most of the matters covered in those memos.

  19. Omega-3 Fatty Acids

    Science.gov (United States)

    Omega-3 fatty acids are used together with lifestyle changes (diet, weight-loss, exercise) to reduce the ... the blood in people with very high triglycerides. Omega-3 fatty acids are in a class of ...

  20. Alternativas biotecnológicas para la producción de ácidos grasos

    Directory of Open Access Journals (Sweden)

    Masson, L.

    2006-09-01

    Full Text Available Fish oils are the main sources of omega-3 (ω3 polyunsaturated acids (PUFA such as eicosapentaenoic (C20:5ω3 and docosahexaenoic (C22:6ω3 acids. World demand for ω3 PUFA shows an increasing trend mainly due to the growth of the aquaculture industry and also due to the increasing demand for specific PUFA used as food supplements. Bacteria, fungi, microalgae and thraustochytrids are biotechnological PUFA alternatives to fish oils. These sources are characterized by specific PUFA profiles whose productivity depends on strain and growth conditions. PUFA content in bacteria is low; microalgae synthesize mixtures of PUFA; fungi system productivity is low due to long  fermentation times. In heterotrofic cultures of thraustochytrids high concentrations of PUFA can be obtained. Moreover, many strains are able to synthesize a single ω3 PUFA. The optimization of fermentation systems and the development of technology capable of large-scale production are needed in order to make these alternatives feasible.Actualmente, los aceites de pescado son la principal fuente de ácidos grasos poliinsaturados (AGPI del tipo omega-3 (ω3 como el ácido eicosapentaenoico (C20:5ω3 y el ácido docosahexaenoico (C22:6ω3. Se estima que en los próximos años la demanda por AGPI ω3 aumentará debido al crecimiento de la industria acuícola y al incremento en la demanda de AGPI específicos para la elaboración de suplementos alimenticios para humanos y animales. Fuentes alternativas para la producción de AGPI ω3 son bacterias, hongos, microalgas y thraustochytridos. La productividad de estos sistemas depende de las cepas y condiciones de fermentación. En general, las bacterias presentan bajas concentraciones de AGPI; las microalgas producen mezclas de AGPI; la productividad de los cultivos de hongos es baja debido a los largos tiempos de fermentación. A diferencia de éstos, los cultivos heterotróficos de thraustochytridos presentan altas concentraciones de AGPI

  1. Estudio del contenido de ácidos grasos superiores en veinte variedades tropicales de soya

    OpenAIRE

    Kocelj Ramírez, Boris; Gutiérrez C., Alvaro

    2009-01-01

    Muy poco se sabe acerca del contenido de ácidos grasos en las diferentes variedades tropicales de soya. En este trabajo se estudiaron veinte variedades tropicales de soya en lo referente a su contenido de aceite y en ácidos grasos. Se determinaros las propiedades físicas y químicas del aceite que lo caracteizan como comestible. El contenido cualitativo y cuantitativo de ácidos grasos individuales se investigó utilizando la técnica de cromatografía de gases. Se analizaron los éteres correspond...

  2. Influencia de la grasa en las propiedades físicas y sensoriales de galletas. Alternativas para la mejora del perfil de acidos grasos

    OpenAIRE

    Tarancón Serrano, Paula Isabel

    2013-01-01

    La presente tesis doctoral se basa en el desarrollo de galletas con menor contenido en grasa mejorando además el perfil lipídico de las mismas. Para ello se reemplazará totalmente la grasa presente en la formulación de las galletas por oleogeles a base de aceites vegetales y diferentes espesantes y se estudiará como afecta dicho reemplazo a las propiedades reológicas de la masa y a las propiedades de textura de la galleta. Por último, se realizará un estudio sensorial para ver la opinión del ...

  3. Removing volatile fatty acids during the anaerobic treatment of pig sewage; Remocion de acidos grasos volatiles durante el tratamiento anaerobio de aguas residuales porcicolas

    Energy Technology Data Exchange (ETDEWEB)

    Vazquez Borges, E.; Mendez Novelo, R.; Magana Pietra, A.; Partinez Pereda, P.; Fernandez Villagomez, G. [Facultad de Ingenieria, Universidad Atuonoma de Yucatan. Mexico (Mexico)

    1997-06-01

    This study examined the behaviour of a hybrid anaerobic digester in treating pig farm sewage. The experimental model consisted of a 208-litre UASB reactor at the bottom and a 195-litre high-rate sedimentator at the top. The digester was installed on a pig farm and its efficiency in removing volatile (acetic and propionic) fatty acids (VFA) was determined with hydraulic retention time (HTR) as the critical parameter for evaluating the anaerobic system`s performance. The results obtained with the five different HRTs used during the experiment are reported. The highest removal rates were obtained with an HRT of 2.8 days: 98% in the UASB, 28% in the sedimentator and 98% in the digester as a whole. An HRT of 1 day gave VFA removal rates of 40%, 12% and 50% in the UASB reactor sedimentator and digest respectively. (Author) 16 refs.

  4. The importance of the fatty acids in breast milk and in lacteal formulae; La importancia de los acidos grasos en la leche materna y en las formulas lacteas

    Energy Technology Data Exchange (ETDEWEB)

    Vega, S.; Gutierrez, R.; Radilla, M.; Ramirez, A.; Perez, J. J.; Schettino, B.; Ramirez, M. L.; Ortiz, R.; Fontecha, J.

    2012-11-01

    The best choice for feeding the newborn child is breast milk, and when it is not possible to breast feed a baby, the breast milk is replaced by lacteal formula, which is why numerous studies focus their attention on the analysis of the diverse components of baby formula as well as functions in the breast fed baby. Fatty acids are components of great nutritional importance in the fetus and in the newborn child. Nowadays it is estimated that the fetus, during the last trimester of the gestational period and the newborn child, during the first six months of life, need a great contribution of araquidonic and docosahexaenoic acids, due to the fact that the speed of transformation of the predecessors to the hepatic level are not sufficient to cover the metabolic requirements of these fatty acids and it is the mother who contributes them through placental transport during gestation and her milk during lactation. The Organization of Food and Agriculture (FAO), the World Health Organization (WHO), the European Society of Gastroenterology, Hepato logy and Pediatric Nutrition (ESPGHAN) and the American Academy of Pediatrics recommend that lacteal formula imitate the composition of the breast milk, especially in the fatty polyunsaturated acids (PUFA). (Author) 61 refs.

  5. The omega-6/omega-3 fatty acid ratio: health implications

    OpenAIRE

    Simopoulos Artemis P.

    2010-01-01

    Today, Western diets are characterized by a higher omega-6 and a lower omega-3 fatty acid intake, whereas during the Paleolithic period when human’s genetic profile was established, there was a balance between omega-6 and omega-3 fatty acids. Their balance is an important determinant for brain development and in decreasing the risk for coronary heart disease (CHD), hypertension, cancer, diabetes, arthritis, and other autoimmune and possibly neurodegenerative diseases. Both omega-6 and omega-3...

  6. Omega-3 Supplements: An Introduction

    Science.gov (United States)

    ... 3 Supplements in the United States What the Science Says If You Are Considering Omega-3 Supplements NCCIH-Funded Research For More Information Key References ©Thinkstock Introduction Omega-3 fatty acids (omega-3s) are a ...

  7. Actividad de la fitasa y comparacion en la composicion quimica, contenido de acido fitico en cuatro variedades de quinua

    National Research Council Canada - National Science Library

    Rosero, Olga; Marounek, Milan; Brenova, Natilia; Lukesova, Daniela

    2013-01-01

    .... El objetivo principal en la investigacion fue encontrar la relacion entre el acido fitico y la actividad de la fitasa en las variedades de quinua Narino procedente de Colombia (QC), quinua Anapquis (QBA...

  8. Observation of the Decay $\\Omega_{C}^{0}\\$ to $\\Omega^{-}e^{+}\\ nu_{e}$

    CERN Document Server

    Ammar, R; Zhao, X; Anderson, S; Frolov, V V; Kubota, Y; Lee, S J; Li, S Z; Poling, R A; Smith, A; Stepaniak, C J; Urheim, J; Ahmed, S; Alam, M S; Jian, L; Saleem, M; Wappler, F; Eckhart, E; Gan, K K; Gwon, C; Hart, T; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pedlar, T K; Thayer, J B; Von Törne, E; Wilksen, T; Zoeller, M M; Muramatsu, H; Richichi, S J; Severini, H; Skubic, P L; Dytman, S A; Nam, S; Savinov, V; Chen, S; Hinson, J W; Lee, J; Miller, D H; Pavlunin, V; Shibata, E I; Shipsey, I P J; Cronin-Hennessy, D; Lyon, A L; Park, C S; Park, W; Thorndike, E H; Coan, T E; Gao, Y S; Liu, F; Maravin, Y; Narsky, I; Stroynowski, R; Artuso, M; Boulahouache, C; Bukin, K; Dambasuren, E; Mountain, R; Skwarnicki, T; Stone, S; Wang, J C; Mahmood, A H; Csorna, S E; Danko, I; Xu, Z; Bonvicini, G; Cinabro, D; Dubrovin, M; McGee, S; Bornheim, A; Lipeles, E; Pappas, S P; Shapiro, A; Sun, W M; Weinstein, A J; Masek, G; Paar, H P; Mahapatra, R; Briere, R A; Chen, G P; Ferguson, T; Tatishvili, G T; Vogel, H; Adam, N E; Alexander, J P; Berkelman, K; Blanc, F; Boisvert, V; Cassel, David G; Drell, P S; Duboscq, J E; Ecklund, K M; Ehrlich, R; Gibbons, L; Gittelman, B; Gray, S W; Hartill, D L; Heltsley, B K; Hsu, L; Jones, C D; Kandaswamy, J; Kreinick, D L; Magerkurth, A; Mahlke-Krüger, H; Meyer, T O; Mistry, N B; Nordberg, E; Patterson, J R; Peterson, D; Pivarski, J; Riley, D; Sadoff, A J; Schwarthoff, H; Shepherd, M R; Thayer, J G; Urner, D; Valant-Spaight, B L; Viehhauser, G; Warburton, A; Weinberger, M; Athar, S B; Avery, P; Breva-Newell, L; Potlia, V; Stöck, H; Yelton, J; Brandenburg, G; Ershov, A; Kim, D Y J; Wilson, R; Benslama, K; Eisenstein, B I; Ernst, J; Gollin, G D; Hans, R M; Karliner, I; Lowrey, N; Marsh, M A; Plager, C; Sedlack, C; Selen, M; Thaler, J J; Williams, J; Edwards, K W

    2002-01-01

    Using the CLEO detector at the Cornell Electron Storage Ring, we have observed the Omega_c (css ground state) in the decay Omega_c -> Omega- e+ nu. We find a signal of 11.4 +- 3.8 (stat) events. The probability that we have observed a background fluctuation is 7.6 x 10-5. We measure BF(Omega_c -> Omega- e+ nu) x sigma(e+ e- -> Omega_c X) = (42.2 +- 14.1 (stat) +- 5.7 (syst)) fb and R = Gamma(Omega_c -> Omega- pi+)/Gamma(Omega_c -> Omega- e+ nu) = 0.41 +- 0.19 (stat) +- 0.04 (syst). This is the first statistically significant observation of an individual decay mode of the Omega_c in e+ e- annhiliation, and the first example of a baryon decaying via beta-emmision, where no quarks from the first generation participate in the reaction.

  9. HÿGADO GRASO NO ALCOHÿLICO

    Directory of Open Access Journals (Sweden)

    LORENA CASTRO S., DRA.

    2015-09-01

    Full Text Available La esteatosis hepática no alcohólica es la acumulación excesiva de grasa en el hígado, en ausencia de causas secundarias y constituye la etiología frecuente de enfermedad hepática crónica sin terapia efectiva demostrada. La enfermedad incluye esteatosis, inflamación, fibrosis/cirrosis y hepatocarcinoma. El fenómeno inicial ocurre en la grasa corporal, con hipertrofia adipocitaria, liberación de adipoquinas y citoquinas pro-inflamatorias, que inducirán resistencia a la insulina. Este fenómeno provocará liberación de ácidos grasos a la circulación, captados por hepatocitos. En su evaluación clínica existen diferentes algoritmos con múltiples variables, limitando la biopsia hepática solo a casos excepcionales. Es esencial modificar el estilo de vida y bajar de peso. En diabéticos, metformina y pioglitazona son de primera elección. Los bloqueadores de la angiotensina son útiles en hipertensos con EHNA. Para prevenir la progresión de la enfermedad y en pacientes no diabéticos, asociar vitamina E. Las estatinas pueden utilizarse dada la asociación con patología cardiovascular.

  10. Omega-3 fatty acids (image)

    Science.gov (United States)

    Omega-3 fatty acids are a form of polyunsaturated fat that the body derives from food. Omega-3s (and omega- ... fish including tuna, salmon, and mackerel. Other important omega 3 fatty acids are found in dark green leafy vegetables, flaxseed ...

  11. A suplementação de ácidos graxos ômega 3 e triglicérides de cadeia média não alteram os indicadores metabólicos em um teste de exaustão La suplementacion de ácidos grasos omega 3 en los trigliceridos de cadena media como alteración en los indicadores metabólicos en un test de agotamiento The supplementation of omega-3 lipids and medium chain triglicerides do not affect metabolic indicators in the exhaustion test

    Directory of Open Access Journals (Sweden)

    Carlos Alexandre Fett

    2004-02-01

    Full Text Available PROPÓSITO: Este estudo compara os efeitos do treinamento de força (TF com ou sem a suplementação de lipídios ômega 3 (W-3 ou triglicérides de cadeia média (TCM, nos indicadores metabólicos em um teste de exaustão (TE. MÉTODOS: Grupo W-3 (GW-3: n = 7, 26,7 ± 6 anos de idade; 82,6 ± 10kg e grupo TCM (GTCM: n = 5, 18,8 ± 1,3 ano de idade; 74,6 ± 9,7kg com 11 meses mínimos em TF. Houve dois momentos de TE: depois de 28 dias somente com TF e coletas de sangue antes (M1a e após (M1d, e após mais 28 dias de TF mais a suplementação com W-3 ou TCM e repetindo o mesmo procedimento (M2a e M2d. RESULTADOS: O hematócrito (Ht, osmolalidade (Os, sódio (Na+ e pressão de dióxido de carbono (PCO2 não tiveram mudanças significativas em nenhum momento, grupo ou D M2 (P > 0,05. A pressão de oxigênio (PO2 aumentou significativamente após TE nos dois momentos e grupos (P PROPÓSITO: Este estudio compara los efectos de entrenamiento de fuerza (TF con o sin la suplementación de lípidos omega 3 (W-3 o triglicéridos de cadena media (TCM, los indicadores metabólicos en un test de agotamiento (TE. MÉTODOS: Grupo W-3 (GW-3: n = 7, 26,7 ± 6 años de idade; 82,6 ± 10 kg y grupo TCM (GTCM: n = 5, 18,8 ± 1,3 año de edad; 74,6 ± 9,7 kg con 11 meses mínimos en TF. Hubo 2 momentos de TE: después de 28 días solamente con TF y colectas de sangre antes (M1a y después (M1d, y después de mas de 28 días de TF más la suplementación con W-3 o TCM y repitiendo el mismo procedimiento (M2a e M2d. RESULTADOS: El hematocrito (Ht, osmolalidad (Os, sodio (Na+ y presión de dióxido de carbono (PCO2 no tuvieron cambios significativos en ningún momento, grupo de D M2 (P > 0,05. La presión de oxígeno (PO2 aumentó significativamente después TE los dos momentos y grupos (P OBJECTIVE: This study compares the effects of strength training (ST with or without supplementation of omega-3 lipids (W-3 or medium chain triglycerides (MCT in metabolic

  12. The omega-6/omega-3 fatty acid ratio: health implications

    Directory of Open Access Journals (Sweden)

    Simopoulos Artemis P.

    2010-09-01

    Full Text Available Today, Western diets are characterized by a higher omega-6 and a lower omega-3 fatty acid intake, whereas during the Paleolithic period when human’s genetic profile was established, there was a balance between omega-6 and omega-3 fatty acids. Their balance is an important determinant for brain development and in decreasing the risk for coronary heart disease (CHD, hypertension, cancer, diabetes, arthritis, and other autoimmune and possibly neurodegenerative diseases. Both omega-6 and omega-3 fatty acids influence gene expression. Because of single nucleotide polymorphisms (SNPs in their metabolic pathways, blood levels of omega-6 and omega-3 fatty acids are determined by both endogenous metabolism and dietary intake making the need of balanced dietary intake essential for health and disease prevention. Whether an omega-6/omega-3 ratio of 3:1 to 4:1 could prevent the pathogenesis of many diseases induced by today’s Western diets (AFSSA, 2010, a target of 1:1 to 2:1 appears to be consistent with studies on evolutionary aspects of diet, neurodevelopment, and genetics. A target of omega-6/omega-3 fatty acid ratio of 1:1 to 2:1 appears to be consistent with studies on evolutionary aspects of diet, neurodevelopment and genetics. A balanced ratio of omega-6/omega-3 fatty acids is important for health and in the prevention of CHD and possibly other chronic diseases.

  13. Estudio del contenido de ácidos grasos superiores en veinte variedades tropicales de soya

    Directory of Open Access Journals (Sweden)

    Boris Kocelj Ramírez

    2009-05-01

    Full Text Available Muy poco se sabe acerca del contenido de ácidos grasos en las diferentes variedades tropicales de soya. En este trabajo se estudiaron veinte variedades tropicales de soya en lo referente a su contenido de aceite y en ácidos grasos. Se determinaros las propiedades físicas y químicas del aceite que lo caracteizan como comestible. El contenido cualitativo y cuantitativo de ácidos grasos individuales se investigó utilizando la técnica de cromatografía de gases. Se analizaron los éteres correspondientes, obtenidos por esterificación catalítica completa con trifluoruro de Boro-metanol. Se encontraron diferencias significativas entre las propiedades de los aceites de las variedades estudiadas. Se identificaron los ácidos: palmítico, esteárico, linoleico y linolénico

  14. Omega-3 Fatty Acids during Pregnancy

    Science.gov (United States)

    OMEGA-3 FATTY ACIDS DURING PREGNANCY S HARE W ITH W OMEN OMEGA-3 FATTY ACIDS DURING PREGNANCY During pregnancy, your ... the foods you eat and vitamins you take. Omega-3 fatty acids (omega-3s) are an important ...

  15. Splitting families and the Noetherian type of $\\beta\\omega-\\omega$

    OpenAIRE

    Milovich, David

    2007-01-01

    Extending some results of Malykhin, we prove several independence results about base properties of $\\beta\\omega-\\omega$ and its powers, especially the Noetherian type $Nt(\\beta\\omega-\\omega)$, the least $\\kappa$ for which $\\beta\\omega-\\omega$ has a base that is $\\kappa$-like with respect to containment. For example, $Nt(\\beta\\omega-\\omega)$ is never less than the splitting number, but can consistently be that $\\omega_1$, $2^\\omega$, $(2^\\omega)^+$, or strictly between $\\omega_1$ and $2^\\omega...

  16. Influencia del sobrepeso y la obesidad en la transferencia placentaria de ácidos grasos en gestantes con diabetes gestacional.

    OpenAIRE

    Blanco Carnero, José Eliseo

    2013-01-01

    PALABRAS CLAVE: Diabetes gestacional, ácidos grasos poliinsaturados, transferencia placentaria, obesidad. El objetivo del estudio fue evaluar la influencia del sobrepeso y obesidad en las gestantes con diabetes gestacional, en su perfil de ácidos grasos en suero materno y en el aporte transplacentario al feto, comparándolo con gestantes normopeso con y sin diabetes gestacional. El sobrepeso y la obesidad en gestantes con DMG no modificó la concentración total de ácidos grasos o sus po...

  17. The Omega spectrometer

    CERN Multimedia

    1972-01-01

    The Omega spectrometer which came into action during the year. An array of optical spark chambers can be seen withdrawn from the magnet aperture. In the 'igloo' above the magnet is located the Plumbicon camera system which collects information from the spark chambers.

  18. Composición de ácidos grasos de los caracoles marinos Phyllonotus pomum y Chicoreus brevifrons (Gastropoda: Muricidae

    Directory of Open Access Journals (Sweden)

    Haydelba D’Armas

    2010-06-01

    Full Text Available Se comparó el contenido de ácidos grasos en los lípidos totales de los caracoles Phyllonotus pomum y Chicoreus brevifrons, recolectados en tres diferentes épocas del año en Punta Arena, estado Sucre, Venezuela. Las concentraciones lipídicas oscilaron entre 0.87 y 1.85%, correspondiendo el valor mínimo y el máximo a C. brevifrons colectado en lluvia y sequía, respectivamente. La esterificación de los ácidos grasos presentes en estos lípidos seguida de la cromatografía de gases permitió la caracterización y cuantificación de los ácidos grasos. En los lípidos totales de las dos especies, en todas las épocas, se observaron elevadas concentraciones de ácidos grasos insaturados (57.21-70.05% seguido de los saturados (20.33-31.94%. Entre los ácidos grasos insaturados, predominaron los de tipo poliinsaturados, exceptuándose el extracto lipídico de P. pomum en época de transición donde las grasas monoinsaturadas fueron las mayoritarias (38.95%. Los ácidos grasos que prevalecieron fueron: C14:0, C16:0, C18:0, C20:1, C22:1 ω- 11, C22:1 ω-9, C18:3 ω-3, C20:5 ω-3 y el C22:6 ω-3, siendo este ϊltimo el predominante entre los αcidos grasos poliinsaturados, presentando porcentajes de distribuciσn comprendidos entre 4.62 y 33.11%. Debido a las altas concentraciones de ácidos grasos poliinsaturados encontradas en ambos caracoles, se recomienda su consumo para la alimentación de los seres humanos.

  19. Determinación de aislados nativos de pseudomonas desulfurizadoras mediante el estudio del perfil de ácidos grasos

    Directory of Open Access Journals (Sweden)

    Edilberto Silva Gómez

    2010-09-01

    Full Text Available Utilizando CGAR se determinó el contenido de ácidos grasos celulares de doce aislados colombianos, Pseudomonas aeruginosa 17, 18, 19, 20, 21, 22 y 103, Pseudomonas sp 23, 24, 25, 26 y 27 con capacidad desulfurizadora, Pseudomonas aeruginosa ATCC 9027 y 10145, Pseudomonas sp ATCC 39327 y Pseudomonas flúores cens. Se encontraron 53 ácidos grasos diferentes, entre saturados e insaturados de cadena lineal, y principalmente hidroxiácidos y ramificados.

  20. Ácidos grasos trans dietarios: interacción nutricional con las diferentes familias de ácidos grasos insaturados

    OpenAIRE

    Saín, Juliana

    2015-01-01

    Fil: Saín, Juliana. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina. Los efectos deletéreos asociados a una elevada ingesta de ácidos grasos trans (AGt) han sido atribuidos, fundamentalmente, a la ingesta de AGt de origen industrial (rico en ácido elaídico). Sin embargo, los AGt de origen natural (carne y leche de animales rumiantes), contienen una proporción significativa de ácido vaccénico (AV), el cual puede ser bioconvertido a ácido ruménico (A...

  1. Omega-3 fiskeolie

    DEFF Research Database (Denmark)

    Lunde, Anita; Sørensen, Jan

    2009-01-01

    Rapport afgrænser sig til evidensbaserede helbredsmæssige gevinster ved et øget indtag af langkædede omega-3, som opnås ved en kost rig på fisk eller som et tilskud af fiskeolier. Der gennemføres en systematisk litteraturgennemgang, som baserer sig på et evidensniveau svarende til styrke A. Det...... betyder, at gennemgangen inkluderer metaanalyser/oversigtsartikler af enten eksperimentelle studier eller observationsstudier, endvidere indgår udvalgte større RCT, som er refereret i meta-analyserne. Sammenfattende findes på baggrund af litteraturgennemgang, at tilskud af omega-3 har effekt på...... hjertesygdom ved at nedsætte mortaliteten. Effekten er mest evident ved personer i særlig risiko for at udvikle hjerte-karsygdom, eller som sekundær/tertiær profylakse. Tilsvarende findes også ved tilskud af omega-3 en forebyggende effekt i forhold til iskæmisk apopleksi. Af mulige virkningsmekanismer viser...

  2. Lightweight HPC beam OMEGA

    Science.gov (United States)

    Sýkora, Michal; Jedlinský, Petr; Komanec, Jan

    2017-09-01

    In the design and construction of precast bridge structures, a general goal is to achieve the maximum possible span length. Often, the weight of individual beams makes them difficult to handle, which may be a limiting factor in achieving the desired span. The design of the OMEGA beam aims to solve a part of these problems. It is a thin-walled shell made of prestressed high-performance concrete (HPC) in the shape of inverted Ω character. The concrete shell with prestressed strands is fitted with a non-stressed tendon already in the casting yard and is more easily transported and installed on the site. The shells are subsequently completed with mild steel reinforcement and cores are cast in situ together with the deck. The OMEGA beams can also be used as an alternative to steel - concrete composite bridges. Due to the higher production complexity, OMEGA beam can hardly substitute conventional prestressed beams like T or PETRA completely, but it can be a useful alternative for specific construction needs.

  3. Damper Spring For Omega Seal

    Science.gov (United States)

    Maclaughlin, Scott T.; Montgomery, Stuart K.

    1993-01-01

    Damper spring reduces deflections of omega-cross-section seal, reducing probability of failure and extending life of seal. Spring is split ring with U-shaped cross section. Placed inside omega seal and inserted with seal into seal cavity. As omega seal compressed into cavity, spring and seal make contact near convolution of seal, and spring becomes compressed also. During operation, when seal dynamically loaded, spring limits deflection of seal, reducing stress on seal.

  4. The Omega spectrometer

    CERN Multimedia

    CERN PhotoLab

    1974-01-01

    The huge superconducting magnet (3 m inside coil diameter, 2 m gap, 18 kGauss) contains a large number of optical spark chambers partly surrounding a hydrogen target which is hit by the beam entering from behind. The half cylindrical aluminium hut houses eight television cameras viewing the spark chambers from the top. The big gas Cerenkov counter in front of the picture (6 m x 4 m x 3 m) which identifies fast forward particles was constructed at Saclay as a contribution of one of the Omega.

  5. Diphasic acido-basic properties of D(octylphenyl)phosphoric acid (DOPPA)

    Energy Technology Data Exchange (ETDEWEB)

    Sella, C.; Cote, G.; Bauer, D. [Laboratoire de Chimie Analytique, Paris (France); Becis, A. [Centre de Developpement des Materiaux, Draria (Algeria)

    1995-07-01

    In the first part of this work, the diphasic acido-basic constant (pka*) of di(octylphenyl)phosphoric acid, denoted hereafter DOPPA or HL, is determined from its experimental diphasic neutralization curve. The pka* value of DOPPA appears to be equal to 2.6 in the presence of 1 mol/dm{sup 3} sodium salt. Such a value is significantly lower than that previously determined for di(2-ethylhexyl) phosphoric acid (DEHPA, pka* = 5.2), 2-ethylhexylphosphonic acid, mono-2-ethylhexyl ester (PC88A, pka* = 7.1) and di(2,4,4-trimethylpentyl)phosphinic acid (CYANEX 272, pka* = 8.7). DOPPA (HL) is definitely more acidic than the other organophosphorus acids because its acidic proton can be easily exchanged with sodium cation to form Na{sup +}HL{sub 2}{sup -} species in organic phase. In the second and final part of the work, molecular modelling is used to model the dimers of various organophosphorus acids. A structure-activity relationship is obtained between the association energies of modelled dimers and their diphasic acido-basic constants. This relationship is then used for predicting the pka* values of DOPPOA and DOPPIA which are the phosphonic and phosphinic analogs of DOPPA, respectively. 16 refs., 5 figs., 4 tabs.

  6. Morphologies of omega band auroras

    Science.gov (United States)

    Sato, Natsuo; Yukimatu, Akira Sessai; Tanaka, Yoshimasa; Hori, Tomoaki

    2017-08-01

    We examined the morphological signatures of 315 omega band aurora events observed using the Time History of Events and Macroscale Interactions during Substorm ground-based all-sky imager network over a period of 8 years. We find that omega bands can be classified into the following three subtypes: (1) classical (O-type) omega bands, (2) torch or tongue (T-type) omega bands, and (3) combinations of classical and torch or tongue (O/T-type) omega bands. The statistical results show that T-type bands occur the most frequently (45%), followed by O/T-type bands (35%) and O-type bands (18%). We also examined the morphologies of the omega bands during their formation, from the growth period to the declining period through the maximum period. Interestingly, the omega bands are not stable, but rather exhibit dynamic changes in shape, intensity, and motion. They grow from small-scale bumps (seeds) at the poleward boundary of preexisting east-west-aligned auroras, rather than via the rotation or shear motion of preexisting east-west-aligned auroras, and do not exhibit any shear motion during the periods of auroral activity growth. Furthermore, the auroral luminosity is observed to increase during the declining period, and the total time from the start of the growth period to the end of the declining period is found to be about 20 min. Such dynamical signatures may be important in determining the mechanism responsible for omega band formation.

  7. Assessment of essential fatty acid and omega 3-fatty acid status by measurement of erythrocyte 20 : 3 omega 9 (Mead acid), 22 : 5 omega 6/20 : 4 omega 6 and 22 : 5 omega 6/22 : 6 omega 3

    NARCIS (Netherlands)

    Smit, EN; Martini, IA; Woltil, HA; Boersma, ER; Muskiet, FAJ

    2002-01-01

    Background. Early suspicion of essential fatty acid deficiency (EFAD) or omega3-deficiency may rather focus on polyunsaturated fatty acid (PUFA) or long-chain PUFA (LCP) analyses than clinical symptoms. We determined cut-off values for biochemical EFAD, omega3-and omega3/22:6omega3 [docosahexaenoic

  8. l aceite de atún como fuente de ácidos grasos ω-3 en el huevo de gallina

    Directory of Open Access Journals (Sweden)

    Vázquez-Valladolid, J. L.

    2005-06-01

    Full Text Available Fish oils are a source of polyunsaturated omega 3 fatty acids (AG ω3, mainly eicosapentaenoic acid (EPA and docosahexaenoic acid (DHA, which supply many benefits to human health. Tuna oil was used as a source of marine 3ω FA to enrich eggs by supplementing the diet of egg-laying hens with tuna oil. One hundred and twenty White Leghorn hens of 90 weeks old were allocated on three treatments with four replicates each, on a completely random design. Treatments consisted of adding 1 % and 2 % of tuna oil to the diets. The total lipids and ω3FA of the eggs were determined. The egg-laying hen dietary tuna oil supplement (1 and 2 % enriched eggs with 300 % more EPA (0.40, 1.37, 1.54 mg/g lipids and DHA (7.90, 24.67, 24.50 mg/g lipids versus the control egg . The ω6:ω3 ratio decreased ( 11.4:1, 3.8:1, 3.0:1 as dietary tuna oil increased. There were no differences (p>0.05 among treatments in productive performance and egg quality, except egg weight which decreased with the tuna oil.Los aceites de pescado son una fuente de lípidos poliinsaturados de origen animal, principalmente de los ácidos grasos omega-3 (AG ω-3, eicosapentaenoico (EPA y docosahexaenoico (DHA, beneficiosos para la salud. En este trabajo se utilizó el aceite de atún como fuente de estos nutrientes en el huevo para consumo. Se utilizaron 120 gallinas blancas Leghorn Isa-Babcock B-300 de 90 semanas de edad, distribuidas al azar en tres tratamientos, con cuatro réplicas cada uno. Los tratamientos consistieron en adicionar 1% y 2% de aceite de atún en la dieta de las gallinas ponedoras. Se determinaron los lípidos totales y AG ω-3 en el huevo, obteniéndose 300 % más de EPA (0,40, 1,37, 1,54 mg/g lípidos y DHA (7,90, 24,67, 24,50 mg/g lípidos al adicionar 1 y 2% de aceite de atún en la dieta de las aves, que en el grupo testigo. La relación ω-6: ω-3 en el huevo disminuyó con el suplemento dietético de aceite de atún (11,4:1, 3,8:1, 3:1, lo mismo ocurri

  9. El aceite de pescado atenua las crisis convulsivas inducidas por hipertermia en ratas neonatas

    OpenAIRE

    Leopoldo E. Flores M.; Miguel A. Guevara; Alfredo Feria-Velasco; Luís Cerdán S.; Marisela Hernández-González

    2008-01-01

    Un alto porcentaje (50-60%) del cerebro en los mamíferos son principalmente grasas o lípidos, de éstos, el 35% son ácidos grasos esenciales, en particular los llamados omegas (O), como el Acido Docosahexanoico (DHA) y el Eicosapentanoico (EPA) llamados omega 3 (O-3). Diversos estudios han mostrado beneficios en la salud con la implementación de los O-3 como agentes terapéuticos en alteraciones cardiovasculares, renales, dérmicas, metabólicas, neurodegenerativas e inmunológicas. Evidencias ...

  10. {Omega}{sup -} signal in WA85

    Energy Technology Data Exchange (ETDEWEB)

    Antinori, F. [CERN, Geneva (Switzerland); Abatzis, S.; Andrighetto, A.; Barnes, R.P.; Bayes, A.C.; Benayoun, M.; Beusch, W.; Bravar, A.; Carney, J.N.; Cruz, B. de la; Di Bari, D.; Dufey, J.P.; Davies, J.P.; Elia, D.; Evans, D.; Fini, R.; French, B.R.; Ghidini, B.; Girone, M.; Helstrup, H.; Holme, A.K.; Jacholkowski, A.; Kahane, J.; Kinson, J.B.; Kirk, A.; Knudson, K.; Lassalle, J.C.; Lenti, V.; Leruste, P.; Manzari, V.; Navach, F.; Narjoux, J.L.; Penzo, A.; Quercigh, E.; Rossi, L.; Safarik, K.; Sene, M.; Sene, R.; Vassiliadis, G.; Villalobos Baillie, O.; Volte, A.; Vortruba, M.F. [Athens Univ., Nuclear Physics Dept. (Greece)]|[Dipt. di Fisica, Univ. Bari (Italy)]|[INFN, Bari (Italy)]|[Bergen Univ. (Norway)]|[Birmingham Univ. (United Kingdom)]|[CERN, Geneva (Switzerland)]|[College de France, 75 - Paris (France)]|[IN2P3, 75 - Paris (France)]|[CIEMAT, Madrid (Spain)]|[INFN, Trieste (Italy); WA85 Collaboration

    1994-01-03

    We have extracted from the full WA85 1990 data set a sample of 14 {Omega}{sup -}+anti {Omega}{sup -} candidates. We describe the selection criteria, and give a measurement of the anti {Omega}{sup -}/{Omega}{sup -} ratio at central rapidity and p{sub T}>1.6 GeV/c. (orig.)

  11. Estudio del contenido de ácidos grasos de los orujos obtenidos como subproductos de vinificación

    OpenAIRE

    Carmona Jiménez, Yolanda; García Moreno, María Valme; García Barroso, Carmelo; Villarrubia, M.L.; Macías Domínguez, Francisco Antonio; Igartuburu Chinchilla, José M.

    2014-01-01

    Los ácidos grasos son componentes importantes de los alimentos de origen vegetal y animal, encontrándose principalmente en aceites y grasas de determinados alimentos. Su uso en alimentación está cada vez más extendido debido a las importantes características beneficiosas que presentan. Los residuos obtenidos durante los procesos involucrados en la elaboración de vinos presentan elevadas concentraciones de compuestos de gran valor añadido entre los que se encuentran los ácidos grasos. En...

  12. Esterificacion quimioselectiva de fitosteroles de madera mediante lipasas

    National Research Council Canada - National Science Library

    Illanes, Andres; Alvarez, Lorena; Alvaro, Gregorio

    2008-01-01

    .... Ambas sustancias son muy similares, lo que impide su separacion por metodos fisicos, siendo la esterificacion selectiva de esta mezcla con esteres de acidos grasos mediante lipasas quimioselectivas...

  13. The Effect of Low Omega-3/Omega-6 Ratio on Auditory Nerve Conduction in Rat Pups.

    Directory of Open Access Journals (Sweden)

    Saeid Farahani

    2015-06-01

    Full Text Available The biological effects of omega-3 and omega-6 fatty acids are determined by their mutual interactions. This interaction extremely affects various functions. Lower consumption of omega-3 during gestation leads to various disorders, even in hearing. We aimed to assess the effect of low omega-3/omega-6 ratios on auditory nerve conduction. In this experimental study, the auditory brainstem response test was performed on 24-day-old rat (n=14. The rats were divided into case (low omega-3/omega-6 ratio during gestation and lactation and control groups. Variables such as P1, P3, and P4 absolute latency period, interpeaks (P3-P4, P1-P3, and P1-P4, and P4/P1 amplitude ratio were measured. We found an increased P4 omega-3/omega-6 ratio in the group with a low omega-3/omega-6 ratio (P0.05.  Also, no significant difference was observed between the groups with respect to the P1-P3 interpeak latency (IPL periods (P>0.05; while the P1-P4 and P3-P4 IPLs were significantly increased in the group with a low omega-3/omega-6 ratio (P<0.05. The P4/P1 amplitude ratio significantly decreased in the group with a low omega-3/omega-6 ratio (P<0.05. Results confirmed the negative effects of low omega-3/omega-6 ratio on the auditory system and hearing.

  14. Cambios en los ácidos grasos de membrana de Microbacterium esteraromatlcum GNP-5 con diferentes temperaturas y osmolaridades

    Directory of Open Access Journals (Sweden)

    Graciela Natalia Pucci

    2006-07-01

    Full Text Available Microbacterium esteraromaticum es un microorganismo que se aísla con frecuencia de Jandfarming o procesos de biorremediación de hidrocarburos en la meseta de la Patagonia central (Argentina y se halla sometido a variaciones de temperatura y a cambios de salinidad que se producen naturalmente. Su adaptabilidad a esos cambios climáticos indujo al estudio de las modificaciones que se producen en su membrana celular para resistirlos. En este trabajo se estudió el efecto conjunto de la temperatura y la concentración de cloruro de sodio sobre la composición de los ácidos grasos de membrana en la cepa de Microbacterium esteraromaticum GNP-5b. M. esteraromaticum utiliza, frente al incremento de la temperatura, la estrategia es aumentar la longitud de sus ácidos grasos de cadenas ramificada impar (17 átomos de carbono con disminución de 15:0 anteiso, así como el porcentaje de ácidos grasos 15:0 iso (de mayor punto de fusión a partir del respectivo anteiso. El aumento de la salinidad modifica la composición de ácidos grasos siguiendo patrones diferentes según sea la temperatura de incubación. A 14 Y28 oc incrementa los 15:0 iso y 17:0 iso en detrimento de sus homólogos anteiso. A 37 "C este grupo de ácidos grasos no sigue los mismos patrones anteriores. La longitud de cadena, expresada como el índice C15jC17, es errática con el aumento de la salinidad.

  15. An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity

    Science.gov (United States)

    Simopoulos, Artemis P.

    2016-01-01

    In the past three decades, total fat and saturated fat intake as a percentage of total calories has continuously decreased in Western diets, while the intake of omega-6 fatty acid increased and the omega-3 fatty acid decreased, resulting in a large increase in the omega-6/omega-3 ratio from 1:1 during evolution to 20:1 today or even higher. This change in the composition of fatty acids parallels a significant increase in the prevalence of overweight and obesity. Experimental studies have suggested that omega-6 and omega-3 fatty acids elicit divergent effects on body fat gain through mechanisms of adipogenesis, browning of adipose tissue, lipid homeostasis, brain-gut-adipose tissue axis, and most importantly systemic inflammation. Prospective studies clearly show an increase in the risk of obesity as the level of omega-6 fatty acids and the omega-6/omega-3 ratio increase in red blood cell (RBC) membrane phospholipids, whereas high omega-3 RBC membrane phospholipids decrease the risk of obesity. Recent studies in humans show that in addition to absolute amounts of omega-6 and omega-3 fatty acid intake, the omega-6/omega-3 ratio plays an important role in increasing the development of obesity via both AA eicosanoid metabolites and hyperactivity of the cannabinoid system, which can be reversed with increased intake of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). A balanced omega-6/omega-3 ratio is important for health and in the prevention and management of obesity. PMID:26950145

  16. An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity

    Directory of Open Access Journals (Sweden)

    Artemis P. Simopoulos

    2016-03-01

    Full Text Available In the past three decades, total fat and saturated fat intake as a percentage of total calories has continuously decreased in Western diets, while the intake of omega-6 fatty acid increased and the omega-3 fatty acid decreased, resulting in a large increase in the omega-6/omega-3 ratio from 1:1 during evolution to 20:1 today or even higher. This change in the composition of fatty acids parallels a significant increase in the prevalence of overweight and obesity. Experimental studies have suggested that omega-6 and omega-3 fatty acids elicit divergent effects on body fat gain through mechanisms of adipogenesis, browning of adipose tissue, lipid homeostasis, brain-gut-adipose tissue axis, and most importantly systemic inflammation. Prospective studies clearly show an increase in the risk of obesity as the level of omega-6 fatty acids and the omega-6/omega-3 ratio increase in red blood cell (RBC membrane phospholipids, whereas high omega-3 RBC membrane phospholipids decrease the risk of obesity. Recent studies in humans show that in addition to absolute amounts of omega-6 and omega-3 fatty acid intake, the omega-6/omega-3 ratio plays an important role in increasing the development of obesity via both AA eicosanoid metabolites and hyperactivity of the cannabinoid system, which can be reversed with increased intake of eicosapentaenoic acid (EPA and docosahexaenoic acid (DHA. A balanced omega-6/omega-3 ratio is important for health and in the prevention and management of obesity.

  17. Challenges when developing omega-3 enriched foods

    OpenAIRE

    JACOBSEN Charlotte

    2010-01-01

    Due to the polyunsaturated nature of omega-3 fatty acids, lipid oxidation is a major challenge when developing omega-3 enriched foods. In multiphase food systems, several factors can affect lipid oxidation and efficacy of antioxidants, added to prevent lipid oxidation. This review discusses the influence of important factors such as oil quality, delivery systems for omega-3 fatty acids, processing conditions, composition of the food matrix on lipid oxidation in different omega-3 enriched food...

  18. Biodisponibilidad de los ácidos grasos de cadena corta: mecanismos de absorción

    OpenAIRE

    Ros Berruezo, Gaspar; Martínez Graciá, C.; Valencia Arques, J.A.

    2011-01-01

    Los ácidos grasos de cadena corta (AGCC) son ácidos monocarboxílicos con una cadena de uno a seis átomos de carbono saturados. Son los principales aniones del colon. Se presentan como ácidos libres en el tracto gastrointestinal de los mamíferos, siendo el producto fi nal de la digestión microbiana de los carbohidratos. Los índices de producción microbiana y de absorción son tan altos que los AGCC son la mayor fuente de energía (70-80%) en mamíferos como la vaca. La contribución...

  19. Reemplazo graso total idiopático del páncreas. Reporte de un caso

    Directory of Open Access Journals (Sweden)

    R. Cobeñas

    2013-01-01

    Full Text Available La lipomatosis pancreática difusa o focal es una entidad que puede ser secundaria a patologías sistémicas (como el síndrome de Shwachman-Diamond, la fibrosis quística u otras o ser idiopática. Se han reportado algunos casos con ausencia de síntomas clínicos o alteraciones en el laboratorio y otros en los que la funcionalidad del páncreas se encontraba comprometida. Aquí presentamos un caso en el cual el hallazgo de reemplazo graso total fue incidental, debido a que se visualizó en una tomografía computada (TC solicitada por otras razones.

  20. Observation of an Excited Charm Baryon OmegaC* Decaying to OmegaC0 Gamma

    CERN Document Server

    Aubert, B; Boutigny, D; Couderc, F; Karyotakis, Yu; Lees, J P; Poireau, V; Tisserand, V; Zghiche, A; Graugès-Pous, E; Palano, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Battaglia, M; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Gill, M S; Groysman, Y; Jacobsen, R G; Kadyk, J A; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; Lynch, G; Mir, L M; Orimoto, T J; Pripstein, M; Roe, N A; Ronan, M T; Wenzel, W A; Del, P; Amo Sanchez; Barrett, M; Ford, K E; Hart, A J; Harrison, T J; Hawkes, C M; Watson, A T; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Peters, K; Schröder, T; Steinke, M; Boyd, J T; Burke, J P; Cottingham, W N; Walker, D; Asgeirsson, D J; Çuhadar-Dönszelmann, T; Fulsom, B G; Hearty, C; Knecht, N S; Mattison, T S; McKenna, J A; Khan, A; Kyberd, P; Saleem, M; Sherwood, D J; Teodorescu, L; Blinov, V E; Bukin, A D; Druzhinin, V P; Golubev, V B; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Todyshev, K Yu; Bondioli, M; Bruinsma, M; Chao, M; Curry, S; Eschrich, I; Kirkby, D; Lankford, A J; Lund, P; Mandelkern, M A; Mommsen, R K; Röthel, W; Stoker, D P; Abachi, S; Buchanan, C; Foulkes, S D; Gary, J W; Long, O; Shen, B C; Wang, K; Zhang, L; Hadavand, H K; Hill, E J; Paar, H P; Rahatlou, S; Sharma, V; Berryhill, J W; Campagnari, C; Cunha, A; Dahmes, B; Hong, T M; Kovalskyi, D; Richman, J D; Beck, T W; Eisner, A M; Flacco, C J; Heusch, C A; Kroseberg, J; Lockman, W S; Nesom, G; Schalk, T; Schumm, B A; Seiden, A; Spradlin, P; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dvoretskii, A; Fang, F; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Mancinelli, G; Meadows, B T; Mishra, K; Sokoloff, M D; Blanc, F; Bloom, P C; Chen, S; Ford, W T; Hirschauer, J F; Kreisel, A; Nagel, M; Nauenberg, U; Olivas, A; Ruddick, W O; Smith, J G; Ulmer, K A; Wagner, S R; Zhang, J; Chen, A; Eckhart, E A; Soffer, A; Toki, W H; Wilson, R J; Winklmeier, F; Zeng, Q; Altenburg, D D; Feltresi, E; Hauke, A; Jasper, H; Merkel, J; Petzold, A; Spaan, B; Brandt, T; Klose, V; Lacker, H M; Mader, W F; Nogowski, R; Schubert, J; Schubert, K R; Schwierz, R; Sundermann, J E; Volk, A; Bernard, D; Bonneaud, G R; Latour, E; Thiebaux, C; Verderi, M; Clark, P J; Gradl, W; Muheim, F; Playfer, S; Robertson, A I; Xie, Y; Andreotti, M; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Petrella, A; Piemontese, L; Prencipe, E; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; De Sangro, R; Finocchiaro, G; Pacetti, S; Patteri, P; Peruzzi, I M; Piccolo, M; Rama, M; Zallo, A; Buzzo, A; Contri, R; Lo, M; Lo Vetere, M; Macri, M M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Brandenburg, G; Chaisanguanthum, K S; Morii, M; Wu, J; Dubitzky, R S; Marks, J; Schenk, S; Uwer, U; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Flack, R L; Nash, J A; Nikolich, M B; Panduro-Vazquez, W; Bard, D J; Behera, P K; Chai, X; Charles, M J; Mallik, U; Meyer, N T; Ziegler, V; Cochran, J; Crawley, H B; Dong, L; Eyges, V; Meyer, W T; Prell, S; Rosenberg, E I; Rubin, A E; Gritsan, A V; Denig, A G; Fritsch, M; Schott, G; Arnaud, N; Davier, M; Grosdidier, G; Höcker, A; Le Diberder, F R; Lepeltier, V; Lutz, A M; Oyanguren, A; Pruvot, S; Rodier, S; Roudeau, P; Schune, M H; Stocchi, A; Wang, W F; Wormser, G; Cheng, C H; Lange, D J; Wright, D M; Chavez, C A; Forster, I J; Fry, J R; Gabathuler, E; Gamet, R; George, K A; Hutchcroft, D E; Payne, D J; Schofield, K C; Touramanis, C; Bevan, A J; Di Lodovico, F; Menges, W; Sacco, R; Cowan, G; Flächer, H U; Hopkins, D A; Jackson, P S; McMahon, T R; Ricciardi, S; Salvatore, F; Wren, A C; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Chia, Y M; Edgar, C L; Lafferty, G D; Naisbit, M T; Williams, J C; Yi, J I; Chen, C; Hulsbergen, W D; Jawahery, A; Lae, C K; Roberts, D A; Simi, G; Blaylock, G; Dallapiccola, C; Hertzbach, S S; Li, X; Moore, T B; Saremi, S; Stängle, H; Cowan, R; Sciolla, G; Sekula, S J; Spitznagel, M; Taylor, F; Yamamoto, R K; Kim, H; Mclachlin, S E; Patel, P M; Robertson, S H; Lazzaro, A; Lombardo, V; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Côté, D; Simard, M; Taras, P; Viaud, F B; Nicholson, H; Cavallo, N; De Nardo, Gallieno; Fabozzi, F; Gatto, C; Lista, L; Monorchio, D; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M A; Raven, G; Snoek, H L; Jessop, C P; LoSecco, J M; Allmendinger, T; Benelli, G; Corwin, L A; Gan, K K; Honscheid, K; Hufnagel, D; Jackson, P D; Kagan, H; Kass, R; Rahimi, A M; Regensburger, J J; Ter-Antonian, R; Wong, Q K; Blount, N L; Brau, J E; Frey, R; Igonkina, O; Kolb, J A; Lu, M; Rahmat, R; Sinev, N B; Strom, D; Strube, J; Torrence, E; Gaz, A; Margoni, M; Morandin, M; Pompili, A; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; Del, L; Buono; La Vaissière, C de; Hamon, O; Hartfiel, B L; Leruste, P; Malcles, J; Ocariz, J; Roos, L; Therin, G; Gladney, L; Biasini, M; Covarelli, R; Angelini, C; Batignani, G; Bettarini, S; Bucci, F; Calderini, G; Carpinelli, M; Cenci, R; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Mazur, M A; Morganti, M; Neri, N; Paoloni, E; Rizzo, G; Walsh, J J; Haire, M; Judd, D; Wagoner, D E; Biesiada, J; Danielson, N; Elmer, P; Lau, Y P; Lü, C; Olsen, J; Smith, A J S; Telnov, A V; Bellini, F; Cavoto, G; D'Orazio, A; Del Re, D; Di Marco, E; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Li Gioi, L; Mazzoni, M A; Morganti, S; Piredda, G; Polci, F; Safai-Tehrani, F; Voena, C; Ebert, M; Schröder, H; Waldi, R; Adye, T; De Groot, N; Franek, B; Olaiya, E O; Wilson, F F; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; Hamel de Monchenault, G; Kozanecki, Witold; Legendre, M; Vasseur, G; Yéche, C; Zito, M; Chen, X R; Liu, H; Park, W; Purohit, M V; Wilson, J R; Allen, M T; Aston, D; Bartoldus, R; Bechtle, P; Berger, N; Claus, R; Coleman, J P; Convery, M R; Cristinziani, M; Dingfelder, J C; Dorfan, J; Dubois-Felsmann, G P; Dujmic, D; Dunwoodie, W M; Field, R C; Glanzman, T; Gowdy, S J; Graham, M T; Grenier, P; Halyo, V; Hast, C; Hrynóva, T; Innes, W R; Kelsey, M H; Kim, P; Leith, D W G S; Li, S; Luitz, S; Lüth, V; Lynch, H L; MacFarlane, D B; Marsiske, H; Messner, R; Müller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Pulliam, T; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Snyder, A; Stelzer, J; Su, D; Sullivan, M K; Suzuki, K; Swain, S K; Thompson, J M; Vavra, J; Van Bakel, N; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wittgen, M; Wright, D H; Yarritu, A K; Yi, K; Young, C C; Burchat, P R; Edwards, A J; Majewski, S A; Petersen, B A; Roat, C; Wilden, L; Ahmed, S; Alam, M S; Bula, R; Ernst, J A; Jain, V; Pan, B; Saeed, M A; Wappler, F R; Zain, S B; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Ritchie, J L; Satpathy, A; Schilling, C J; Schwitters, R F; Izen, J M; Lou, X C; Ye, S; Bianchi, F; Gallo, F; Gamba, D; Bomben, M; Bosisio, L; Cartaro, C; Cossutti, F; Della Ricca, G; Dittongo, S; Lanceri, L; Vitale, L; Azzolini, V; Lopez-March, N; Martínez-Vidal, F; Banerjee, Sw; Bhuyan, B; Brown, C M; Fortin, D; Hamano, K; Kowalewski, R V; Nugent, I M; Roney, J M; Sobie, R J; Back, J J; Harrison, P F; Latham, T E; Mohanty, G B; Pappagallo, M; Band, H R; Chen, X; Cheng, B; Dasu, S; Datta, M; Flood, K T; Hollar, J J; Kutter, P E; Mellado, B; Mihályi, A; Pan, Y; Pierini, M; Prepost, R; Wu, S L; Yu, Z; Neal, H; al, et

    2006-01-01

    We report the first observation of an excited singly-charm baryon OmegaC* (css) in the radiative decay OmegaC0 Gamma, where the OmegaC0 baryon is reconstructed in the decays to the final states Omega-pi+, Omega-pi+pi0, Omega-pi+pi-pi+, and Cascade-K-pi+pi+. This analysis is performed using a dataset of 230.7 fb$-1} collected by the BABAR detector at the PEP-II asymmetric-energy B Factory at the Stanford Linear Accelerator Center. The mass difference between the OmegaC* and the OmegaC0 baryons is measured to be 70.8 +/- 1.0 (stat) +/- 1.1 (syst) MeV/c2. We also measure the ratio of inclusive production cross sections of OmegaC* and OmegaC0 in e+e- annihilation.

  1. Estabilidad oxidativa y calidad sensorial de carne de pollo enriquecida con acidos grasos n-3 proveniente de fuentes de origen vegetal y animal, protegida con vitamina E y selenio orgánico.

    OpenAIRE

    GALLINGER, CLAUDIA ISABEL

    2015-01-01

    [EN] Despite people attitudes concerning healthy eating, western diets still show a low intake of n-3 polyunsaturated fatty acid (PUFA). Among Argentinean people the consumption of fish meat is relatively poor, being beef and chicken meat their main sources of protein. A viable way of increasing the consumption of n-3 PUFA is to raise the intake of products enriched with them. Chicken meat is rated in second place in the consumption of meat in Argentina. This meat, like others, is a nutrit...

  2. Modeling of an immobilized lipase tubular reactor for the production of glycerol and fatty acids from oils; Modelado de un reactor tubular de lipasas inmovilizadas para la produccion de glicerol y acidos grasos a partir de aceites

    Energy Technology Data Exchange (ETDEWEB)

    Oddone, S.; Grasselli, M.; Cuellas, A.

    2010-07-01

    Advances in the design of a bioreactor in the fats and oils industry have permitted the hydrolysis of triglycerides in mild conditions and improved productivity while avoiding the formation of unwanted byproducts. The present work develops a mathematical model that describes the hydrolytic activity of a tubular reactor with immobilized lipases for the production of glycerol and fatty acids from the oil trade. Runge Kuttas numerical method of high order has been applied, considering that there is no accumulation of the substratum in the surface of the membrane, where the enzyme is. At the same time, different equations based on the kinetic model of Michaelis Mentens and the Ping-Pong bi-bi mechanism were examined. Experimental data in discontinuous systems are the basis for the development of the quantitative mathematical model that was used to simulate the process computationally. The obtained results allow for optimizing both the operative variables and the economic aspects of industrial processes. (Author)

  3. Huevos enriquecidos con omega 3

    OpenAIRE

    Viteri, Evelyn

    2013-01-01

    El presente trabajo es una contribución al estudio de usos de ingredientes no tradicionales; harina de algas, Macrocystis pyrifera, y la inclusión en raciones para aves de postura destinado a aumentar la concentración de omega 3 del huevo. Objetivo: Evaluar en la alimentación de la gallina la inclusión de harina de alga marina Macrocystis pyrifera con el fin de aumentar el valor de omega 3 en el huevo, y el grado de aceptación de un producto elaborado con el mismo en estudiante...

  4. SÍNDROME DE HÍGADO GRASO EN UN CABALLO CRIOLLO COLOMBIANO

    Directory of Open Access Journals (Sweden)

    J. M. Cruz

    2013-01-01

    Full Text Available El objetivo de este trabajo fue discutir sobre los hallazgos clínicos, los exámenes de patología clínica realizados y su utilidad como indicadores de pronóstico en un pacien - te equino hembra con hígado graso. Se describe el caso de una yegua de raza criollo colombiano que ingresó al servicio de consulta externa del Hospital Veterinario Diego Villegas Toro de la Universidad de Caldas con signos de tránsito intestinal lento y cólico. Previamente, el veterinario remitente inició un tratamiento con fluidos y aceite cristal oral sin resultados satisfactorios. Se realizó un examen físico completo y pruebas paraclínicas (creatinina, BUN, albúmina, fibrinógeno, fosfatasa alcalina [FA], gamma glutamiltransferasa [GGT], alanina aminotransferasa [ALT], aspartato aminotransferasa [AST] y análisis de orina que sugirieron disfunción hepática y compactación del colon mayor. Se instauró un tratamiento dirigido a favorecer el peristaltismo y la eliminación fecal y se dispensó soporte para coadyuvar a la función hepática. Durante la hospita - lización se observaron signos clínicos compatibles con falla hepática, encefalopatía e compactación grave; finalmente, el equino murió. Durante la necropsia se confirmó compactación del colon mayor a nivel de la flexura esternal y peritonitis. El diagnóstico histopatológico fue hígado graso y peritonitis. Se concluye que la falla hepática puede asociarse con compactación del colon.

  5. $\\omega$-Euclidean domain and Laurent series

    Directory of Open Access Journals (Sweden)

    O. M. Romaniv

    2016-06-01

    Full Text Available It is proved that a commutative domain $R$ is $\\omega$-Euclidean if and only if the ring of formal Laurent series over $R$ is $\\omega$-Euclidean domain. It is also proved that every singular matrice over ring of formal Laurent series $R_{X}$ are products of idempotent matrices if $R$ is $\\omega$ -Euclidean domain.

  6. Evaluation of the therapeutic effect of Nigella sativa crude oil and its blend with omega-3 fatty acid-rich oils in a modified hepatorenal syndrome model in rats

    Directory of Open Access Journals (Sweden)

    Al-Okbi, S. Y.

    2015-12-01

    Full Text Available In the present study, the hepato and reno-protective effect of Nigella sativa crude oil and its binary blend with omega-3 fatty acid-rich oils (fish and flaxseed oils was studied in a modified hepatorenal syndrome model (MHRS in rats. MHRS was induced through feeding a high fructose diet followed by an intraperitoneal injection of galactosamine hydrochloride. Nigella oil and its different blends were given as a daily oral dose to MHRS rats. Two control groups of MHRS and normal healthy rats were run. Different biochemical and nutritional parameters were assessed. The induction of MHRS produced liver and kidney dysfunction, and elevated oxidative stress, an inflammatory biomarker, endothelin 1, and plasma cholesterol. Reduced plasma high density lipoprotein cholesterol, albumin and Ca and elevated urinary N-acetyl-β-D-Glucosaminidase and liver fats were noticed. The administration of Nigella crude oil that originally had 0.2% total omega-3 fatty acids or its blend with fish oil (17.9% omega-3 or flaxseed oil (42.1% omega-3 significantly improved all biochemical parameters of MHRS. There was no significant difference in the biochemical parameters among the different oil treated groups regardless of the omega-3 fatty acid content. This may point out to the potential profound effect of the volatile oil fraction of Nigella crude oil which may compensates for its low omega-3 content.En el presente estudio, el efecto hepato- y reno-protector de aceites crudos de Nigella sativa y su mezcla binaria con aceites ricos en ácidos grasos omega-3 (pescado y aceites de linaza fue estudiado en un modelo modificado de síndrome hepatorenal (MHRS en ratas. MHRS fue inducido a través de la alimentación de una dieta alta en fructosa seguido de la inyección intraperitoneal de clorhidrato de galactosamina. Diferentes aceites fueron suministrados como dosis oral diaria a ratas con MHRS. Se realizaron dos grupos de control de MHRS y ratas sanas normales. Se

  7. FY10 LLNL OMEGA Experimental Programs

    Energy Technology Data Exchange (ETDEWEB)

    Tommasini, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2010-09-28

    In FY10, LLNL conducted several campaigns on the OMEGA laser system and on the EP laser system, as well as campaigns that used the OMEGA and EP beams jointly. Overall LLNL led 301 target shots involving the OMEGA laser system and 96 target shots involving the EP laser system. Approximately 40% of the total number of shots (137 OMEGA shots, 32 EP shots) shots supported the National Ignition Campaign (NIC). The remainder was dedicated to experiments for High-Energy-Density Physics (HED) (164 OMEGA shots, 64 EP shots).

  8. Descripción sistemática del "pez graso" del lago de tota (boyacá)

    OpenAIRE

    Miles, Cecil

    2012-01-01

    La especie P. totae se distingue fácilmente de los demás miembros conocidos de la familia Pygidiidae por sus anillos grasos, que semejan una serie de llantas de automóvil, y especialmente por las dos ampollas occipitales de forma peculiarísima; por su apariencia repugnante; por su olor a manteca; y por la posición adelantada de la unión de las membranas branquiales.

  9. Descripción sistemática del "Pez Graso" del Lago de Tota (Boyacá

    Directory of Open Access Journals (Sweden)

    Miles Cecil

    1942-11-01

    Full Text Available La especie P. totae se distingue fácilmente de los demás miembros conocidos de la familia Pygidiidae por sus anillos grasos, que semejan una serie de llantas de automóvil, y especialmente por las dos ampollas occipitales de forma peculiarísima; por su apariencia repugnante; por su olor a manteca; y por la posición adelantada de la unión de las membranas branquiales.

  10. Efecto del uso de aceite de girasol oxidado sobre la digestibilidad de los ácidos grasos

    OpenAIRE

    Villaverde Haro, Cecília

    2003-01-01

    Es habitual incluir grasas en piensos para avicultura como fuente de energia, de ácidos grasos y de otros compuestos liposolubles como ciertas vitaminas. El uso de subproductos generados en procesos de fritura y refinado, los cuales han sufrido procesos de oxidación, puede provocar una disminución del valor nutritivo del alimento y posibles efectos negativos sobre la salud del animal.

  11. On topological groups admitting a base at identity indexed with $\\omega^\\omega$

    OpenAIRE

    Leiderman, Arkady G.; Pestov, Vladimir G.; Tomita, Artur H.

    2015-01-01

    A topological group $G$ is said to have a local $\\omega^\\omega$-base if the neighbourhood system at identity admits a monotone cofinal map from the directed set $\\omega^\\omega$. In particular, every metrizable group is such, but the class of groups with a local $\\omega^\\omega$-base is significantly wider. The aim of this article is to better understand the boundaries of this class, by presenting new examples and counter-examples. Ultraproducts and non-arichimedean ordered fields lead to natur...

  12. Perfiles de ácidos grasos totales y libres en embutidos crudo-curados tradicionales de Galicia

    Directory of Open Access Journals (Sweden)

    Carballo, Javier

    2004-09-01

    Full Text Available The total and free fatty acid contents were studied in ready for consumption samples of four different varieties of traditional dry-fermented sausages made in Galicia (NW of Spain: Chorizo gallego, Chorizo de cebolla, Androlla and Botillo. No significant differences (p>0.05 were observed in the content of the different total fatty acids among the four sausage varieties. The total fatty acids profile was very similar in the four varieties: the most abundant total fatty acid was oleic (45% of total fatty acids, followed by palmitic (21%, linoleic (14%, estearic (13% and palmitoleic (2%; this profile basically coincides with those described by other authors in pork fat. The total average content of free fatty acids was 2176 mg/100 g of fat in Chorizo gallego, 5223 mg/100 g of fat in Chorizo de cebolla, 2308 mg/100 g of fat in Androlla and 183 mg/100 g of fat in Botillo. These average values in Chorizo gallego, Chorizo de cebolla and Androlla were found in the range of values described for other dry-fermented sausage varieties; the average value in Botillo was clearly lower than those decribed for other fermented sausages. In the four sausage varieties the most abundant free fatty acid was oleic, followed by linoleic, palmitic and estearic. This free fatty acid profile coincides with those described in literature for other dry-fermented sausages. The average content of each individual free fatty acid was significantly (p0.05 were observed in the individual free fatty acid content between Chorizo gallego and Androlla. Using discriminant analysis 100% of the samples of Chorizo de cebolla and Botillo were correctly classified and differentiated from their content in individual free fatty acids. However, only 50% of samples of Chorizo gallego and 25% of samples of Androlla were correctly classified.Se estudiaron los contenidos en ácidos grasos totales y libres en muestras de producto final de cuatro embutidos tradicionales gallegos: Chorizo gallego

  13. ACTIVIDAD ANTIOXIDANTE Y PERFIL DE ÁCIDOS GRASOS DE LAS SEMILLAS DE JABUTICABA (Myrciaria cauliflora BERG

    Directory of Open Access Journals (Sweden)

    NEUZA JORGE

    2011-01-01

    Full Text Available Múltiples compuestos naturales encontrados en frutas, cereales y vegetales presentan actividad antioxidante. Este trabajo tuvo como objetivo caracterizar las semillas de jabuticaba ( Myrciaria cauliflora Berg en cuanto a su composición proximal y potencial antioxidante, y evaluar el perfil de ácidos grasos en el aceite extraído de las mismas. Para la obtención del extracto, las semillas deshidratadas y trituradas fueron extraídas con alcohol etílico por 30 minutos, en la proporción de 1:3 de semillas:alcohol etílico, bajo agitación continua, a temperatura ambiente. Seguidamente, la mezcla fue filtrada y el sobrenadante deshidratado a 40 ºC con la finalidad de determinar, por pesaje di- recto, rendimiento en materia seca del extracto. De acuerdo con los resultados obtenidos, las semillas de jabuticaba mostraron ser fuente de carbohidratos totales importante, además presentaron actividad antioxidante relevante. El aceite de jabuticaba presentó porcentaje significativo de ácidos grasos poliinsaturados, con predominancia del ácido linoleico y α -linolénico, ácidos grasos esenciales.

  14. Actividad antioxidante y perfil de ácidos grasos de las semillas de jabuticaba (Myrciaria cauliflora Berg

    Directory of Open Access Journals (Sweden)

    Jorge Neuza

    2011-08-01

    Full Text Available Este trabajo tuvo como objetivo caracterizar las semillas de jabuticaba (Myrciaria cauliflora Berg en cuanto a su composición proximal y potencial antioxidante y evaluar el perfil de ácidos grasos en el aceite extraído de las mismas. Para la obtención del extracto, las semillas deshidratadas y trituradas fueron extraídas con alcohol etílico por 30 minutos, en la proporción de 1:3 de semillas:alcohol etílico, bajo agitación continua, a temperatura ambiente. Seguidamente, la mezcla fue filtrada y el sobrenadante fue deshidratado a 40oC con la finalidad de determinar, por pesaje directo, el rendimiento en materia seca del extracto. De acuerdo con los resultados obtenidos, las semillas de jabuticaba mostraron ser una importante fuente de carbohidratos totales, además presentaron una relevante actividad antioxidante. El aceite de jabuticaba presentó porcentaje significativa de ácidos grasos poliinsaturados, con predominancia del ácido linoleico y α-linolénico, ácidos grasos esenciales.

  15. Acido-basic control of the thermoelectric properties of poly(3,4-ethylenedioxythiophene)tosylate (PEDOT-Tos) thin films

    DEFF Research Database (Denmark)

    Khan, Zia Ullah; Bubnova, Olga; Jafari, Mohammad Javad

    2015-01-01

    study the variation in the thermoelectric properties by a simple acido-basic treatment. The emphasis of this study is to elucidate the chemical changes induced by acid (HCl) or base (NaOH) treatment in PEDOT-Tos thin films using various spectroscopic and structural techniques. We could identify changes...

  16. A nitrogen-doped graphene/gold nanoparticle/formate dehydrogenase bioanode for high power output membrane-less formic acid/O2 biofuel cells.

    Science.gov (United States)

    Gai, Panpan; Ji, Yusheng; Chen, Yun; Zhu, Cheng; Zhang, Jianrong; Zhu, Jun-Jie

    2015-03-21

    A high power output, membrane-less formic acid/O2 enzymatic biofuel cell was fabricated, in which nitrogen-doped graphene was proven to be effective for recycling the NAD(+)/NADH cofactor at a nitrogen-doped graphene/gold nanoparticle/formate dehydrogenase bioanode in the catalytic oxidation of formic acid.

  17. Omega-3 deficiency impairs honey bee learning

    Science.gov (United States)

    Arien, Yael; Dag, Arnon; Zarchin, Shlomi; Masci, Tania

    2015-01-01

    Deficiency in essential omega-3 polyunsaturated fatty acids (PUFAs), particularly the long-chain form of docosahexaenoic acid (DHA), has been linked to health problems in mammals, including many mental disorders and reduced cognitive performance. Insects have very low long-chain PUFA concentrations, and the effect of omega-3 deficiency on cognition in insects has not been studied. We show a low omega-6:3 ratio of pollen collected by honey bee colonies in heterogenous landscapes and in many hand-collected pollens that we analyzed. We identified Eucalyptus as an important bee-forage plant particularly poor in omega-3 and high in the omega-6:3 ratio. We tested the effect of dietary omega-3 deficiency on olfactory and tactile associative learning of the economically highly valued honey bee. Bees fed either of two omega-3–poor diets, or Eucalyptus pollen, showed greatly reduced learning abilities in conditioned proboscis-extension assays compared with those fed omega-3–rich diets, or omega-3–rich pollen mixture. The effect on performance was not due to reduced sucrose sensitivity. Omega-3 deficiency also led to smaller hypopharyngeal glands. Bee brains contained high omega-3 concentrations, which were only slightly affected by diet, suggesting additional peripheral effects on learning. The shift from a low to high omega-6:3 ratio in the Western human diet is deemed a primary cause of many diseases and reduced mental health. A similar shift seems to be occurring in bee forage, possibly an important factor in colony declines. Our study shows the detrimental effect on cognitive performance of omega-3 deficiency in a nonmammal. PMID:26644556

  18. Omega-3 deficiency impairs honey bee learning.

    Science.gov (United States)

    Arien, Yael; Dag, Arnon; Zarchin, Shlomi; Masci, Tania; Shafir, Sharoni

    2015-12-22

    Deficiency in essential omega-3 polyunsaturated fatty acids (PUFAs), particularly the long-chain form of docosahexaenoic acid (DHA), has been linked to health problems in mammals, including many mental disorders and reduced cognitive performance. Insects have very low long-chain PUFA concentrations, and the effect of omega-3 deficiency on cognition in insects has not been studied. We show a low omega-6:3 ratio of pollen collected by honey bee colonies in heterogenous landscapes and in many hand-collected pollens that we analyzed. We identified Eucalyptus as an important bee-forage plant particularly poor in omega-3 and high in the omega-6:3 ratio. We tested the effect of dietary omega-3 deficiency on olfactory and tactile associative learning of the economically highly valued honey bee. Bees fed either of two omega-3-poor diets, or Eucalyptus pollen, showed greatly reduced learning abilities in conditioned proboscis-extension assays compared with those fed omega-3-rich diets, or omega-3-rich pollen mixture. The effect on performance was not due to reduced sucrose sensitivity. Omega-3 deficiency also led to smaller hypopharyngeal glands. Bee brains contained high omega-3 concentrations, which were only slightly affected by diet, suggesting additional peripheral effects on learning. The shift from a low to high omega-6:3 ratio in the Western human diet is deemed a primary cause of many diseases and reduced mental health. A similar shift seems to be occurring in bee forage, possibly an important factor in colony declines. Our study shows the detrimental effect on cognitive performance of omega-3 deficiency in a nonmammal.

  19. Ácidos grasos trans en aceites hidrogenados: implicaciones técnicas y nutricionales

    Directory of Open Access Journals (Sweden)

    Barrera-Arellano, D.

    1993-10-01

    Full Text Available Customers are increasingly paying attention to fats and oils because they are strongly health related. Many points are still confusing about this, but certainly there is one that will soon become public concern: the presence of trans fatty acids in hydrogenated fats and their products. Natural fats and oils from vegetable origin lack this trans isomers. Even though the production of the trans isomers during hydrogenation is unavoidable it can be controlled and minimized. The presence of these components modify technical characteristics as well as introduce problems and alterations in health and nutritional aspects. High trans fatty acids values (up 62% were found in Brazilian products. A relevant effect in solid content (SFC at low temperatures was observed but no influence in the softening point. Possible nutritional and health effects related to trans fatty acids will be discussed.

    Actualmente, las grasas y aceites son alimentos observados con mucha atención por los consumidores, por su estrecha relación entre ellos y la salud. Uno de los puntos todavía confusos y que ciertamente vendrá rápidamente a tornarse de dominio público, es la presencia de ácidos grasos trans en grasas hidrogenadas y productos que las contienen. En aceites y grasas de origen vegetal estos isómeros trans están ausentes, y son producidos durante la hidrogenación, este fenómeno es inevitable, pero puede ser controlado y minimizado. La presencia de estos compuestos modifican tanto las características técnicas como también, se sospecha ocasionan problemas y alteraciones desde el punto de vista nutricional y de salud. En productos hidrogenados brasileños fueron encontrados valores elevados de ácidos trans (hasta 62%, observándose un efecto notable en el contenido de sólidos (SFC a bajas temperaturas y ninguna influencia en el punto de reblandecimiento «softening point». Posibles efectos nutricionales y de salud relacionados con ácidos grasos trans

  20. Cuantificación de ácidos grasos a partir de biomasa microalgal

    Directory of Open Access Journals (Sweden)

    García Sánchez, J. L.

    1993-12-01

    Full Text Available Long chain polyunsaturated fatty acids are focusing the interest of researchers as long as analytical techniques are being improved. The Lepage and Roy direct transesterification method is being widely used to measure fatty acid content of microalgae which are proposed as potential sources of these products. In this paper, the physical state of the biomass to be analyzed is studied. Comparison has been stated between lyophilized biomass and wet biomass just harvested. Furthermore, the amount of sample and the number of methyl ester extractions have also been studied. From the statistical analysis carried out, wet biomass to fatty acid determination and the adequate range of sample are proposed. Three methyl ester extractions improve the resolution of GC analysis.

    El interés creciente por los ácidos grasos poliinsaturados de cadena larga viene favorecido por la mejora de las técnicas de análisis. La metodología de transesterificación directa propuesta por Lepage y Roy está siendo ampliamente utilizada para la determinación del contenido en ácidos grasos de microalgas, consideradas como potenciales fuentes de estos productos. En el presente trabajo, se analiza la influencia del estado físico de la biomasa analizada, seca, normalmente por liofilización, o húmeda recién cosechada del cultivo. Asimismo, se analiza el efecto de la cantidad de biomasa empleada y del número de extracciones de los esteres metílicos obtenidos. Del estudio estadístico realizado se pone de manifiesto la importancia del estado físico de la muestra, aconsejándose el uso de biomasa directamente obtenida del cultivo. Se proponen los intervalos de cantidad de biomasa para metilación, así como la conveniencia de realizar tres extracciones previas a la inyección en el cromatógrafo, que favorece la resolución del análisis.

  1. Balancing omega-6 and omega-3 fatty acids in ready-to-use therapeutic foods (RUTF)

    DEFF Research Database (Denmark)

    Brenna, J Thomas; Akomo, Peter; Bahwere, Paluku

    2015-01-01

    Ready-to-use therapeutic foods (RUTFs) are a key component of a life-saving treatment for young children who present with uncomplicated severe acute malnutrition in resource limited settings. Increasing recognition of the role of balanced dietary omega-6 and omega-3 polyunsaturated fatty acids...... with altered PUFA content and looked at the effects on circulating omega-3 docosahexaenoic acid (DHA) status as a measure of overall omega-3 status. Supplemental oral administration of omega-3 DHA or reduction of RUTF omega-6 linoleic acid using high oleic peanuts improved DHA status, whereas increasing omega......-3 alpha-linolenic acid in RUTF did not. The results of these two small studies are consistent with well-established effects in animal studies and highlight the need for basic and operational research to improve fat composition in support of omega-3-specific development in young children as RUTF use...

  2. FY14 LLNL OMEGA Experimental Programs

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, R. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Fournier, K. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Baker, K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Barrios, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bernstein, L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Brown, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Celliers, P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Chen, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Coppari, F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Fratanduono, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Johnson, M. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Huntington, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Jenei, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kraus, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ma, T. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Martinez, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); McNabb, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Millot, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Moore, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Nagel, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Park, H. S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Patel, P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Perez, F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ping, Y. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pollock, B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ross, J. S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rygg, J. R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Smith, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Zylstra, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Collins, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Landen, O. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wan, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hsing, W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2014-10-13

    In FY14, LLNL’s High-Energy-Density Physics (HED) and Indirect Drive Inertial Confinement Fusion (ICF-ID) programs conducted several campaigns on the OMEGA laser system and on the EP laser system, as well as campaigns that used the OMEGA and EP beams jointly. Overall these LLNL programs led 324 target shots in FY14, with 246 shots using just the OMEGA laser system, 62 shots using just the EP laser system, and 16 Joint shots using Omega and EP together. Approximately 31% of the total number of shots (62 OMEGA shots, 42 EP shots) shots supported the Indirect Drive Inertial Confinement Fusion Campaign (ICF-ID). The remaining 69% (200 OMEGA shots and 36 EP shots, including the 16 Joint shots) were dedicated to experiments for High- Energy-Density Physics (HED). Highlights of the various HED and ICF campaigns are summarized in the following reports.

  3. FY15 LLNL OMEGA Experimental Programs

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, R. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Baker, K. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Barrios, M. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Beckwith, M. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Casey, D. T. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Celliers, P. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Chen, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Coppari, F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Fournier, K. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Fratanduono, D. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Frenje, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Huntington, C. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kraus, R. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Lazicki, A. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Martinez, D. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); McNaney, J. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Millot, M. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pak, A. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Park, H. S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ping, Y. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pollock, B. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Smith, R. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wehrenberg, C. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Widmann, K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Collins, G. W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Landen, O. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wan, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hsing, W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-12-04

    In FY15, LLNL’s High-Energy-Density Physics (HED) and Indirect Drive Inertial Confinement Fusion (ICF-ID) programs conducted several campaigns on the OMEGA laser system and on the EP laser system, as well as campaigns that used the OMEGA and EP beams jointly. Overall these LLNL programs led 468 target shots in FY15, with 315 shots using just the OMEGA laser system, 145 shots using just the EP laser system, and 8 Joint shots using Omega and EP together. Approximately 25% of the total number of shots (56 OMEGA shots and 67 EP shots, including the 8 Joint shots) supported the Indirect Drive Inertial Confinement Fusion Campaign (ICF-ID). The remaining 75% (267 OMEGA shots and 86 EP shots) were dedicated to experiments for High-Energy-Density Physics (HED). Highlights of the various HED and ICF campaigns are summarized in the following reports.

  4. Using Caenorhabditis elegans to Uncover Conserved Functions of Omega-3 and Omega-6 Fatty Acids

    OpenAIRE

    WATTS, JENNIFER L.

    2016-01-01

    The nematode Caenorhabditis elegans is a powerful model organism to study functions of polyunsaturated fatty acids. The ability to alter fatty acid composition with genetic manipulation and dietary supplementation permits the dissection of the roles of omega-3 and omega-6 fatty acids in many biological process including reproduction, aging and neurobiology. Studies in C. elegans to date have mostly identified overlapping functions of 20-carbon omega-6 and omega-3 fatty acids in reproduction a...

  5. Supervivencia a largo plazo de los injertos grasos Long-term survival with fat grafting

    Directory of Open Access Journals (Sweden)

    J. Planas

    2006-03-01

    Full Text Available Presentamos varios casos de pérdida de volumen de diferentes etiologías y en distintas regiones corporales y faciales tratadas mediante injertos de tejido graso autólogo según la técnica de lipoestructura. En ningún caso se realizó sobrecorrección del defecto en ningún caso. La evolución con un seguimiento máximo de 7 años y mínimo de 1 año no mostró disminución del volumen obtenido en el acto quirúrgico en la gran mayoría de los casos. Debido a los resultados obtenidos creemos que el injerto de grasa autólogo es el método de elección para restaurar volúmenes con fines estéticos o reconstructivos.Volume loss in several facial and body areas was treated by means of autologous fatty tissue grafts with lipostructure technique. There were no cases of overcorrection. The patients’ course, with a maximum follow-up of 7 years and a minimum of 1 year did not evidence any loss of the surgically restored tissue volume in the majority of cases. The above results suggest that autologous fat grafts are the method of choice to restore volume for both cosmetic and reconstructive purposes.

  6. Omega-3s in food emulsions

    DEFF Research Database (Denmark)

    Jacobsen, Charlotte

    2008-01-01

    There is an increasing interest in the use of healthy long chain omega-3 oils in foods. Incorporation of omega-3 oils into foods decreases their oxidative stability and therefore precautions need to be taken to avoid lipid oxidation. This review summarises the major factors to take...... into consideration when developing food emulsions enriched with omega-3 oils and examples on how oxidation can be reduced in products such as mayonnaise, spreads, milk, yoghurt are also given....

  7. Using Caenorhabditis elegans to Uncover Conserved Functions of Omega-3 and Omega-6 Fatty Acids

    Science.gov (United States)

    Watts, Jennifer L.

    2016-01-01

    The nematode Caenorhabditis elegans is a powerful model organism to study functions of polyunsaturated fatty acids. The ability to alter fatty acid composition with genetic manipulation and dietary supplementation permits the dissection of the roles of omega-3 and omega-6 fatty acids in many biological process including reproduction, aging and neurobiology. Studies in C. elegans to date have mostly identified overlapping functions of 20-carbon omega-6 and omega-3 fatty acids in reproduction and in neurons, however, specific roles for either omega-3 or omega-6 fatty acids are beginning to emerge. Recent findings with importance to human health include the identification of a conserved Cox-independent prostaglandin synthesis pathway, critical functions for cytochrome P450 derivatives of polyunsaturated fatty acids, the requirements for omega-6 and omega-3 fatty acids in sensory neurons, and the importance of fatty acid desaturation for long lifespan. Furthermore, the ability of C. elegans to interconvert omega-6 to omega-3 fatty acids using the FAT-1 omega-3 desaturase has been exploited in mammalian studies and biotechnology approaches to generate mammals capable of exogenous generation of omega-3 fatty acids. PMID:26848697

  8. Hadronic decay properties of newly observed $\\Omega_c$ baryons

    OpenAIRE

    Zhao, Ze; Ye, Dan-Dan; Zhang, Ailin

    2017-01-01

    Hadronic decay widths of the newly observed charmed strange baryons, $\\Omega_c(3000)^0$, $\\Omega_c(3050)^0$, $\\Omega_c(3066)^0$, $\\Omega_c(3090)^0$ and $\\Omega_c(3119)^0$ have been calculated in a $^3P_0$ model. Our results indicate that $\\Omega_c(3066)^0$ and $\\Omega_c(3090)^0$ can be interpreted as the $1P-$wave $\\Omega_{c2}(\\frac{3}{2}^-)$ or $\\Omega_{c2}(\\frac{5}{2}^-)$. Though the measured masses of $\\Omega_c(3000)^0$, $\\Omega_c(3050)^0$ and $\\Omega_c(3119)^0$ are lower than existed theo...

  9. Identificación de ácidos grasos contenidos en los aceites extraídos a partir de semillas de tres diferentes especies de frutas

    Directory of Open Access Journals (Sweden)

    Andrés Felipe Cerón

    2012-04-01

    Full Text Available En este estudio se midió el rendimiento de aceite y la composición de ácidos grasos presentes en semillas de las frutas andinas tropicales: lulo de la variedad castilla (Solanum quitoense, mora de la variedad castilla (Rubus glaucus y maracuyá (Passiflora edulis. La extracción se hizo con solventes en un extractor Soxhlet utilizando éter etílico al 99.8% de pureza y punto de ebullición 40 - 60 °C. Para identificar los ácidos grasos se empleó cromatografía de gases con detector FID (GC-FID. Los rendimientos en aceite fueron de 8.5% para lulo, 12.2% para mora y 21.2% para maracuyá. Los ácidos grasos encontrados en semillas de lulo fueron palmítico (15.6% y linoléico (58.1%; en semillas de mora linoléico (50.1% y linolénico (25.1% y en las de maracuyá palmítico (15.44%, oleico (15.47% y linoléico (63.1%. El contenido graso de las semillas evaluadas evidenció su potencial como materia prima oleaginosa y por sus contenidos de ácidos grasos se pueden considerar una fuente importante de componentes para las industrias alimentaria, farmacéutica y cosmética.

  10. Universal graphs at $\\aleph_{\\omega_1+1}$

    OpenAIRE

    Davis, Jacob

    2016-01-01

    Starting from a supercompact cardinal we build a model in which $2^{\\aleph_{\\omega_1}}=2^{\\aleph_{\\omega_1+1}}=\\aleph_{\\omega_1+3}$ but there is a jointly universal family of size $\\aleph_{\\omega_1+2}$ of graphs on $\\aleph_{\\omega_1+1}$. The same technique will work for any uncountable cardinal in place of $\\omega_1$.

  11. ¿Pueden los ácidos grasos omega 3 y 6 contrarrestar los efectos negativos de la obesidad en la gestación?

    OpenAIRE

    Escobar H,Johana; Estrada A,Lina; Gómez G,Lina; Gil V,Aura María; Cadavid J,Angela

    2013-01-01

    La obesidad se define como el exceso de grasa corporal que pone en peligro la salud, aumentando la morbilidad y la mortalidad de la población. El índice de masa corporal es el indicador más usado para la determinación de la obesidad, y durante el embarazo se calcula de acuerdo a las modificaciones de Rosso-Mardones. Según la Organización Mundial de la Salud, la prevalencia de la obesidad en el embarazo oscila desde 1,8 hasta 25,3%, y la obesidad antes y durante la gestación constituye un impo...

  12. Enriquecimiento de huevos con ácidos grasos omega-3 mediante la suplementación con semilla de lino (linum usitatissimum) en la dieta

    National Research Council Canada - National Science Library

    Betancourt Fernández, Liliana; Díaz, Gonzalo

    2009-01-01

    .... Materials and methods. Four levels of flaxseed amounts were evaluated: 0% (L0), 10% (L10), 15% (L15) and 20% (L20). We evaluated the fatty acid composition in the egg s yolk, as well as quantity and quality of eggs produced...

  13. Statistical study of auroral omega bands

    Science.gov (United States)

    Partamies, Noora; Weygand, James M.; Juusola, Liisa

    2017-09-01

    The presence of very few statistical studies on auroral omega bands motivated us to test-use a semi-automatic method for identifying large-scale undulations of the diffuse aurora boundary and to investigate their occurrence. Five identical all-sky cameras with overlapping fields of view provided data for 438 auroral omega-like structures over Fennoscandian Lapland from 1996 to 2007. The results from this set of omega band events agree remarkably well with previous observations of omega band occurrence in magnetic local time (MLT), lifetime, location between the region 1 and 2 field-aligned currents, as well as current density estimates. The average peak emission height of omega forms corresponds to the estimated precipitation energies of a few keV, which experienced no significant change during the events. Analysis of both local and global magnetic indices demonstrates that omega bands are observed during substorm expansion and recovery phases that are more intense than average substorm expansion and recovery phases in the same region. The omega occurrence with respect to the substorm expansion and recovery phases is in a very good agreement with an earlier observed distribution of fast earthward flows in the plasma sheet during expansion and recovery phases. These findings support the theory that omegas are produced by fast earthward flows and auroral streamers, despite the rarity of good conjugate observations.

  14. FY16 LLNL Omega Experimental Programs

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, R. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ali, S. J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Benstead, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Celliers, P. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Coppari, F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Eggert, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Erskine, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Panella, A. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Fratanduono, D. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hua, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Huntington, C. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Jarrott, L. C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Jiang, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kraus, R. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Lazicki, A. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); LePape, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Martinez, D. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); McNaney, J. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Millot, M. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Moody, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pak, A. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Park, H. S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ping, Y. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pollock, B. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rinderknecht, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ross, J. S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rubery, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sio, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Smith, R. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Swadling, G. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wehrenberg, C. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Collins, G. W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Landen, O. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wan, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hsing, W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-12-01

    In FY16, LLNL’s High-Energy-Density Physics (HED) and Indirect Drive Inertial Confinement Fusion (ICF-ID) programs conducted several campaigns on the OMEGA laser system and on the EP laser system, as well as campaigns that used the OMEGA and EP beams jointly. Overall, these LLNL programs led 430 target shots in FY16, with 304 shots using just the OMEGA laser system, and 126 shots using just the EP laser system. Approximately 21% of the total number of shots (77 OMEGA shots and 14 EP shots) supported the Indirect Drive Inertial Confinement Fusion Campaign (ICF-ID). The remaining 79% (227 OMEGA shots and 112 EP shots) were dedicated to experiments for High-Energy-Density Physics (HED). Highlights of the various HED and ICF campaigns are summarized in the following reports. In addition to these experiments, LLNL Principal Investigators led a variety of Laboratory Basic Science campaigns using OMEGA and EP, including 81 target shots using just OMEGA and 42 shots using just EP. The highlights of these are also summarized, following the ICF and HED campaigns. Overall, LLNL PIs led a total of 553 shots at LLE in FY 2016. In addition, LLNL PIs also supported 57 NLUF shots on Omega and 31 NLUF shots on EP, in collaboration with the academic community.

  15. Statistical study of auroral omega bands

    Directory of Open Access Journals (Sweden)

    N. Partamies

    2017-09-01

    Full Text Available The presence of very few statistical studies on auroral omega bands motivated us to test-use a semi-automatic method for identifying large-scale undulations of the diffuse aurora boundary and to investigate their occurrence. Five identical all-sky cameras with overlapping fields of view provided data for 438 auroral omega-like structures over Fennoscandian Lapland from 1996 to 2007. The results from this set of omega band events agree remarkably well with previous observations of omega band occurrence in magnetic local time (MLT, lifetime, location between the region 1 and 2 field-aligned currents, as well as current density estimates. The average peak emission height of omega forms corresponds to the estimated precipitation energies of a few keV, which experienced no significant change during the events. Analysis of both local and global magnetic indices demonstrates that omega bands are observed during substorm expansion and recovery phases that are more intense than average substorm expansion and recovery phases in the same region. The omega occurrence with respect to the substorm expansion and recovery phases is in a very good agreement with an earlier observed distribution of fast earthward flows in the plasma sheet during expansion and recovery phases. These findings support the theory that omegas are produced by fast earthward flows and auroral streamers, despite the rarity of good conjugate observations.

  16. Effect of omega-3 on auditory system

    Directory of Open Access Journals (Sweden)

    Vida Rahimi

    2014-01-01

    Full Text Available Background and Aim: Omega-3 fatty acid have structural and biological roles in the body 's various systems . Numerous studies have tried to research about it. Auditory system is affected a s well. The aim of this article was to review the researches about the effect of omega-3 on auditory system.Methods: We searched Medline , Google Scholar, PubMed, Cochrane Library and SID search engines with the "auditory" and "omega-3" keywords and read textbooks about this subject between 19 70 and 20 13.Conclusion: Both excess and deficient amounts of dietary omega-3 fatty acid can cause harmful effects on fetal and infant growth and development of brain and central nervous system esspesially auditory system. It is important to determine the adequate dosage of omega-3.

  17. Desarrollo de alimentos tipo snack de bajo contenido graso a partir de discos de manzana verde

    OpenAIRE

    Tavera Quiroz, María José

    2015-01-01

    Esta investigación se basó en el desarrollo de productos tipo snack bajos en grasa a partir de manzana verde Granny Smith (Malus domestica). Se desarrollaron snacks a partir de manzanas verdes estudiando diferentes alternativas de cocción (fritado, horneado o su combinación) con el objetivo de obtener productos con menor contenido graso que los tradicionales pero con las propiedades que los consumidores valoran en los mismos, como el color y la textura crocante. Para ello se analizó...

  18. Derivados de amida de ácidos grasos con anfetaminas para el tratamiento de desórdenes alimenticios

    OpenAIRE

    Joglar Tamargo, Jesús; Clapés Saborit, Pere; Covas, María Isabel

    2009-01-01

    La presente invención se refiere a nuevos derivados amidas de ácidos grasos conjugados con anfetaminas, que se comportan como ligandos duales de los receptores cannabionides tipo 1 (CB 1) Y del subtipo alfa de los receptores activados por el proliferador de peroxisomas (PPARalfa), y como potentes agentes inhibidores de la oxidación de la Lipoproteína de Baja Densidad (LDL), así como a su procedimiento de preparación, y su utilización como herramienta farmacológica y co...

  19. Ácidos grasos, vitamina E y rotulado nutricional de margarinas y esparcibles comercializados en Bogotá, Colombia

    Directory of Open Access Journals (Sweden)

    Lorena A. Bolívar C.

    2010-05-01

    Conclusiones: 91% de las margarinas y esparcibles más comercializados en cinco localidades de Bogotá en agosto de 2008 es libre de ácidos grasos trans (< 0,5 g/porción y en promedio aportan 13% de la RDA de vitamina E/porción. Sólo 40% de los productos analizados declara todos los nutrientes de carácter obligatorio según la Resolución 0288 de 2008.

  20. Physical-chemical properties of C-phycocyanin isolated from an acido-thermophilic eukaryote, Cyanidium caldarium.

    Science.gov (United States)

    Kao, O H; Edwards, M R; Berns, D S

    1975-01-01

    C-Phycocyanin from an acido-thermophilic eukaryotic alga, Cyanidium caldarium, was characterized with respect to subunit structure, absorption spectrum and fluorescence properties and was found to be similar to C-phycocyanins from mesophilic sources. The pH-dependence of fluorescence polarization and the changes in sedimentation velocity as a function of pH, concentration and temperature indicate the presence of extremely large amounts of unusually stable 19S aggregates. It was not possible to disaggregate this phycocyanin completely to monomer under normal conditions. The amino acid composition is similar to that of phycocyanins from other thermophilic and halophilic sources. The isoelectric point of this C-phycocyanin was 5.11, an unusually high value. The properties of this C-phycocyanin suggest an increase in protein stability as its mode of adaptation to the environmental stress of high temperature. Images Fig. 7. PMID:239703

  1. A study of the lunisolar secular resonance $2dot{omega}+dot{Omega}=0$

    Directory of Open Access Journals (Sweden)

    Alessandra eCelletti

    2016-03-01

    Full Text Available The dynamics of small bodies around the Earth has gained a renewed interest,since the awareness of the problems that space debris can cause in thenearby future. A relevant role in space debris is played by lunisolarsecular resonances, which might contribute to an increase of the orbitalelements, typically of the eccentricity. We concentrate our attention onthe lunisolar secular resonance described by the relation$2dot{omega}+dot{Omega}=0$, where $omega$ and $Omega$ denotethe argument of perigee and the longitude of the ascending node of the space debris.We introduce three different models with increasing complexity. We show that the growth in eccentricity, as observed in space debris located in the MEO region at the inclination about equal to $56^circ$, can be explained as a natural effect of the secular resonance $2dot{omega}+dot{Omega}=0$, while the chaotic variations of the orbital parameters are the result of interaction and overlapping of nearby resonances.

  2. A protective lipidomic biosignature associated with a balanced omega-6/omega-3 ratio in fat-1 transgenic mice.

    NARCIS (Netherlands)

    Astarita, G.; McKenzie, J.H.; Wang, B.; Strassburg, K.; Doneanu, A.; Johnson, J.; Baker, A.; Hankemeier, T.; Murphy, J.; Vreeken, R.J.; Langridge, J.; Kang, J.X.

    2014-01-01

    A balanced omega-6/omega-3 polyunsaturated fatty acid (PUFA) ratio has been linked to health benefits and the prevention of many chronic diseases. Current dietary intervention studies with different sources of omega-3 fatty acids (omega-3) lack appropriate control diets and carry many other

  3. Estudio de la densidad y de la viscosidad de algunos ácidos grasos puros

    Directory of Open Access Journals (Sweden)

    Cedeño González, Fidel Oscar

    1999-10-01

    Full Text Available An experimental study is carried out according to ASTM analysis methods of two physical properties, density and viscosity, of palmitic, stearic and oleic fatty acids; compounds which are present in the deodorization effluents of edible oils, with a view to their physics chemical characterisation needed for the design of surface condensers and freezers that could be employed in the recovery of these effluents. The measures are carried out every 5 °C, from temperatures close to those of solidification in each compound, of great interest in our study, to 100 °C. The values of these properties are contrasted with those that appear in the literature, and the experimental measures are correlated. Values of the density are also obtained applying Rackett's equation and those of dynamic viscosity using Andrade's equation, and then compared with experimental measures. Experimental data of the dynamic viscosity for oleic acid at low temperatures (between 0 and 24 °C are also presented, because of their interest in the design of the previously mentioned equipment.

    En este trabajo se realiza un estudio experimental de acuerdo con los métodos de análisis de la ASTM de las propiedades físicas, densidad y viscosidad en los ácidos grasos palmítico, esteárico y oleico; compuestos que están presentes en los efluentes de la desodorización de aceites comestibles, con vistas a la caracterización físico química necesaria en el diseño de condensadores y congeladores de superficie que pueden aplicarse a la recuperación de estos efluentes. Las medidas se realizan de 5 en 5 °C entre temperaturas muy próximas a las de solidificación en cada compuesto, de gran interés en nuestro estudio, y los 100 °C. Se contrastan los valores de estas propiedades, con los que aparecen en la literatura y se correlacionan las medidas experimentales. También se obtienen valores de la densidad aplicando la ecuación de Rackett y de la viscosidad din

  4. El índice de anisidina como medida del deterioro latente de un material graso

    Directory of Open Access Journals (Sweden)

    Grompone, M. A.

    1991-02-01

    Full Text Available Although the peroxide value is a common measurement of lipid oxidation, its use is limited to the initial stages of oxidation. Since peroxides are vulnerable to further decomposition, the complete oxidative history of the oil may not be revealed. The anisidine test a measure of secondary oxidation products, is considered useful in that it shows the past history of the oil. Effects of accelerated storage test on the anisidine and peroxide values of commercially samples were studied. The results obtained indicate that the anisidine value is a good method to predict storage stability of fats. Some processing steps in producing edible fats and oils were studied. Bleaching clay performs decomposition of oxidation products and this effect alone would reduce the peroxide value. Comparative studies were undertaken to determine the effects of bleaching on the anisidine value. Analysis of damaged oils before and after deodorization showed that little reduction of anisidine value occurred.

    El índice de anisidina como medida del deterioro latente de un material graso. A pesar de que el índice de peróxido es una medida corriente de la oxidación de los lípidos, su uso está limitado a las etapas iniciales de dicha reacción. Como los peróxidos pueden sufrir descomposiciones posteriores, la historia oxidativa completa del aceite no se conoce por ellos. Se considera que el índice de anisidina, una medida de los productos de la oxidación secundaria, es muy útil para evaluar el pasado del aceite. Se estudiaron los efectos del almacenamiento acelerado de muestras comerciales sobre los índices de anisidina y de peróxido. Los resultados obtenidos indican que el índice de anisidina es un buen método para predecir dicha estabilidad. Se estudiaron algunas etapas del procesamiento de las grasas y aceites comestibles. Las arcillas de blanqueo producen la descomposición de los productos de oxidación y este efecto sólo puede reducir el

  5. Perfil de ácidos grasos de diversas especies de pescados consumidos en México

    Directory of Open Access Journals (Sweden)

    María Isabel Castro González

    2013-12-01

    Full Text Available Los factores bióticos y abióticos determinan la composición de ácidos grasos AG en los peces, información relevante por la asociación existente entre su consumo y los beneficios para la salud humana. El objetivo de esta investigación fue identificar la variación en la concentración de AG, según diferentes factores, en diez especies marinas de pescado comestible en México: Euthynnus alletteratus, Sciaenops ocellatus, Bairdiella chrysoura, Sphyraena guachancho, Symphurus elongatus, Istiophorus platypterus, Ophichthus rex, Eugerres plumieri, Eucinostomus entomelas y Oreochromis mossambicus. La determinación de AG se llevó a cabo mediante cromatografía de gases. El contenido de lípidos totales varió entre 0.93 y 1.95g/100g en E. entomelas y O. mossambicus, respectivamente. E. alletteratus, B. chrysoura, S elongatus, I. platypterus, O. rex y E. plumieri presentaron el siguiente orden en la concentración de AG: AG poliinsaturados AGPAG saturados AGSAG monoinsaturados AGM. S. ocellatus, S. guachancho y E. entomelas: AGSAGPAGM; mientras que tan solo O. mossambicus presentó AGSAGMAGP. Este tuvo la mayor concentración de AGS 559.40mg/100g y AGM 422.60mg/100g, mientras que B. chrysoura presentó el mayor contenido mg/100g de AGP 663.03, AGn-3 514.03, EPA+DHA 506.10 y AGn-6 145.80. Factores bióticos y abióticos influyeron significativamente en la concentración de AG. Las especies subtropicales presentaron una concentración 42.1 mayor de EPA+DHA que las tropicales. Los valores presentados pueden cambiar según modificaciones en el ecosistema y en las características de cada especie, sin embargo, el conocimiento aquí generado es útil para mejorar las recomendaciones sobre el consumo de pescado.

  6. Effects of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on Breast Cancer

    OpenAIRE

    Shapiro, Lisa

    1999-01-01

    Epidemiological observations reveal that Japanese women, who eat a low-fat diet with a high fish consumption, have a much lower incidence of breast cancer than North American and European women who eat a higher fat diet rich in omega-6 polyunsaturated fats. This observation has been supported by experimental research that omega-6 fatty acids like corn and safflower oil can promote tumor growth, and omega-3 fatty acids found in fish oil can inhibit tumor growth. Omega-3 fatty acids serve a pro...

  7. An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity

    OpenAIRE

    Artemis P. Simopoulos

    2016-01-01

    In the past three decades, total fat and saturated fat intake as a percentage of total calories has continuously decreased in Western diets, while the intake of omega-6 fatty acid increased and the omega-3 fatty acid decreased, resulting in a large increase in the omega-6/omega-3 ratio from 1:1 during evolution to 20:1 today or even higher. This change in the composition of fatty acids parallels a significant increase in the prevalence of overweight and obesity. Experimental studies have sugg...

  8. Kurepa trees and spectra of $\\mathcal{L}_{\\omega_1,\\omega}$-sentences

    OpenAIRE

    Sinapova, Dima; Souldatos, Ioannis

    2017-01-01

    We construct a \\emph{single} $\\mathcal{L}_{\\omega_1,\\omega}$-sentence $\\psi$ that codes Kurepa trees to prove the consistency of the following: (1) The spectrum of $\\psi$ is consistently equal to $[\\aleph_0,\\aleph_{\\omega_1}]$ and also consistently equal to $[\\aleph_0,2^{\\aleph_1})$, where $2^{\\aleph_1}$ is weakly inaccessible. (2) The amalgamation spectrum of $\\psi$ is consistently equal to $[\\aleph_1,\\aleph_{\\omega_1}]$ and $[\\aleph_1,2^{\\aleph_1})$, where again $2^{\\aleph_1}$ is weakly ina...

  9. ÁCIDOS GRASOS EN LA DIETA DIABETES MELLITUS E INSULINO RESISTENCIA Unsaturated fatty acids intake and its relationship with insulin resistance in diabetes mellitus patients

    Directory of Open Access Journals (Sweden)

    Clara Eugenia Pérez G

    2006-06-01

    Full Text Available La resistencia a la insulina es característica de la diabetes mellitus tipo 2. Como parte del tratamiento se recomienda los diabéticos, sustituir en las dietas los ácidos grasos saturados y el colesterol por ácidos grasos monoinsaturados; sin que estén del todo claro los mecanismos bioquímicos que beneficiarían a los pacientes. Es probable, entre otros mecanismos, que los ácidos grasos monoin­saturados aumenten la sensibilidad a la insulina. Esta revisión analiza la relación entre el tipo de ácido graso en la dieta y la resistencia a insulina en la diabetes mellitus tipo 2.One of the most important characteristic in the obese patient with diabetes mellitus type 2 is the noticeable insulin resistance. Physicians recommended to these patients replace saturated fatty acids and cholesterol by greater dietary monounsaturated fatty acids content, without being absolutely sure about the biochemical mechanisms by which, this change, might help then. It is possible that monounsaturated fatty acids increase sensitivity to the insulin within another mechanism. The following revision is focused in the relationship between the type of dietary fatty acids ingestion and the resistance to insulin in diabetes mellitus type 2 patients.

  10. OMEGA for the Future of Biofuels

    Science.gov (United States)

    Trent, Jonathan

    2010-01-01

    OMEGA: Offshore Membrane Enclosure for Growing Algae. To develop a photobioreactor (PBR) for growing algae (Oil, food, fertilizer) that does not compete with agriculture for land (deployed offshore), water or fertilizer (uses/treats wastewater).

  11. Omega-3 fats: Good for your heart

    Science.gov (United States)

    ... medlineplus.gov/ency/patientinstructions/000767.htm Omega-3 fats: Good for your heart To use the sharing ... 3 fatty acids are a type of polyunsaturated fat . We need these fats to build brain cells ...

  12. Challenges when developing omega-3 enriched foods

    Directory of Open Access Journals (Sweden)

    JACOBSEN Charlotte

    2010-07-01

    Full Text Available Due to the polyunsaturated nature of omega-3 fatty acids, lipid oxidation is a major challenge when developing omega-3 enriched foods. In multiphase food systems, several factors can affect lipid oxidation and efficacy of antioxidants, added to prevent lipid oxidation. This review discusses the influence of important factors such as oil quality, delivery systems for omega-3 fatty acids, processing conditions, composition of the food matrix on lipid oxidation in different omega-3 enriched foods (milk, yoghurt, mayonnaise and mayonnaise-based salads, dressing, energy bar and fish paté. Moreover, the effect of different antioxidants (tocopherol, EDTA, lactoferrin, caffeic acid, ascorbic acid, ascorbyl palmitate, propyl gallate, gallic acid, as well as lipophilized antioxidants is compared in different food systems.

  13. Challenges when developing omega-3 enriched foods

    DEFF Research Database (Denmark)

    Jacobsen, Charlotte

    2010-01-01

    Due to the polyunsaturated nature of omega-3 fatty acids, lipid oxidation is a major challenge when developing omega-3 enriched foods. In multiphase food systems, several factors can affect lipid oxidation and efficacy of antioxidants, added to prevent lipid oxidation. This review discusses...... the influence of important factors such as oil quality, delivery systems for omega-3 fatty acids, processing conditions, composition of the food matrix on lipid oxidation in different omega-3 enriched foods (milk, yoghurt, mayonnaise and mayonnaise-based salads, dressing, energy bar and fish paté). Moreover......, the effect of different antioxidants (tocopherol, EDTA, lactoferrin, caffeic acid, ascorbic acid, ascorbyl palmitate, propyl gallate, gallic acid, as well as lipophilized antioxidants) is compared in different food systems....

  14. A host-microbiome interaction mediates the opposing effects of omega-6 and omega-3 fatty acids on metabolic endotoxemia

    OpenAIRE

    Kaliannan, Kanakaraju; Wang, Bin; Li, Xiang-yong; Kim, Kui-Jin; Kang, Jing X.

    2015-01-01

    Metabolic endotoxemia, commonly derived from gut dysbiosis, is a primary cause of chronic low grade inflammation that underlies many chronic diseases. Here we show that mice fed a diet high in omega-6 fatty acids exhibit higher levels of metabolic endotoxemia and systemic low-grade inflammation, while transgenic conversion of tissue omega-6 to omega-3 fatty acids dramatically reduces endotoxemic and inflammatory status. These opposing effects of tissue omega-6 and omega-3 fatty acids can be e...

  15. North Pacific Omega Navigation System Validation.

    Science.gov (United States)

    1981-12-31

    based upon comparisons with "Loran-C, radar and visual" whose absolute accuracy as references could not be assessed. Similarly, the M/S Nopal Lane...Mellon ..................................... A-82 A5.1.5 M/S Nopal Lane ................... ......... .... .. A-83 A5.1.6 Submarine Omega Performance...From Omega Log of M/S NOPAL LANE .................... A-84 A5-2 Western Airlines Flights - 1978 .......................... A-85 AA-1 Difference Between

  16. Identificación de ácidos grasos contenidos en los aceites extraídos a partir de semillas de tres diferentes especies de frutas

    Directory of Open Access Journals (Sweden)

    Cerón Andres Felipe

    2012-11-01

    Full Text Available En este estudio se midió el rendimiento de aceite y la composición de ácidos grasos presentes en se- millas de las frutas andinas tropicales: lulo de la variedad castilla (Solanum quitoense, mora de la variedad castilla (Rubus glaucus y maracuyá (Passiflora edulis. La extracción se hizo con solventes en un extractor Soxhlet utilizando éter etílico al 99.8% de pureza y punto de ebullición 40 - 60 ºC. Para identificar los ãcidos grasos se empleó cromatografia de gases con detector FID (GC-FID. Los rendimientos en aceite fueron de 8.5% para lulo, 12.2% para mora y 21.2% para maracuyá. Los ácidos grasos encontrados en semillas de lulo fueron palmítico (15.6% y linoléico (58.1%; en semillas de mora linoléico (50.1% y linolénico (25.1% y en las de maracuyá palmítico (15.44%, oleico (15.47% y linoléico (63.1%. El contenido graso de las semillas evaluadas evidenció su potencial como materia prima oleaginosa y por sus contenidos de ácidos grasos se pueden considerar una fuente importante de componentes para las industrias alimentaria, farmacéutica y cosmética

  17. Fatty acid composition of cold-adapted carotenogenic basidiomycetous yeasts Composición de ácidos grasos de levaduras carotenogénicas

    Directory of Open Access Journals (Sweden)

    D. Libkind

    2008-12-01

    Full Text Available We studied fatty acids (FAs profiles in six carotenoid-producing yeast species isolated from temperate aquatic environments in Patagonia. Total FAs ranged from 2 to 15% of dry biomass. Linoleic, oleic, palmitic and α-linolenic acids were the major FAs constituents, which accounted for as much as 40%, 34%, 13% and 9% of total FAs, respectively. The proportion of each FA varied markedly depending on the taxonomic affiliation of the yeast species and on the culture media used. The high percentage of polyunsaturated fatty acids (PUFAs found in Patagonian yeasts, in comparison to other yeasts, is indicative of their cold-adapted metabolism. Our results suggest that Patagonian yeasts may be considered an interesting source of essential PUFAs.Se estudiaron los ácidos grasos de seis especies de levaduras productoras de carotenoides aisladas de ambientes acuáticos templados de la Patagonia. El contenido total de ácidos grasos fluctuó entre 2 y 15% de la biomasa seca. Los ácidos linoleico, oleico, palmítico y α-linolénico fueron los mayoritarios y contribuyeron en un 40%, 34%, 13% y 9% al total de ácidos grasos, respectivamente. La proporción de cada ácido graso varió de modo considerable según la filiación taxonómica de la especie y el medio de cultivo utilizado. El alto porcentaje de ácidos grasos poliinsaturados (PUFA observado en las levaduras patagónicas, en comparación con levaduras de otros orígenes, es indicativo de un metabolismo adaptado al frío. Nuestros resultados sugieren que las levaduras patagónicas pueden ser consideradas una fuente interesante de PUFA esenciales.

  18. Contenido en isómeros geométricos de los ácidos grasos en helados comerciales españoles

    Directory of Open Access Journals (Sweden)

    León, M.

    2003-03-01

    Full Text Available Eight samples of different varieties of commercial ice-creams sold in Spain were analysed for their fatty acid composition, with relevance on their trans-fatty acid profile. Saturated fatty acids occurred in the largest proportions in all samples (mean=68,1%, followed by monounsaturated (mean=21,1% and polyunsaturated fatty acids (mean=5,2%. Trans fatty acids were detected in all samples ranging from 0,5%-19%, mean value 5,7%. Statistical analysis (cluster analysis based on their fatty acid profile (saturated, monounsaturated and polyunsaturated and trans fatty acids showed three groups of samples, depending on the main source of fat employed.Ocho muestras de distintas variedades de helados comercializados en España han sido analizadas para determinar su contenido en ácidos grasos de cadena media y larga, con especial interés en el contenido en ácidos grasos trans. La fracción mayoritaria en todos los casos, está constituida por los ácidos grasos saturados, que presentan un valor medio del 68,1%, seguido de la fracción de monoinsaturados (media=21,1% y poliinsaturados (media=5,1%. El contenido en ácidos grasos trans, detectado en todas las muestras, oscila entre 0,5%-19%, con un valor medio de 5,7%. El análisis estadístico (análisis cluster realizado, basándonos en el contenido en ácidos grasos saturados, monoinsaturados, poliinsaturados y trans, ha permitido diferenciar tres grupos distintos de helados según la fuente de grasa mayoritaria empleada en su elaboración.

  19. Omega-3 fatty acids and cardiovascular disease.

    Science.gov (United States)

    Jain, A P; Aggarwal, K K; Zhang, P-Y

    2015-01-01

    Cardioceuticals are nutritional supplements that contain all the essential nutrients including vitamins, minerals, omega-3-fatty acids and other antioxidants like a-lipoic acid and coenzyme Q10 in the right proportion that provide all round protection to the heart by reducing the most common risks associated with the cardiovascular disease including high low-density lipoprotein cholesterol and triglyceride levels and factors that contribute to coagulation of blood. Omega-3 fatty acids have been shown to significantly reduce the risk for sudden death caused by cardiac arrhythmias and all-cause mortality in patients with known coronary heart disease. Omega-3 fatty acids are also used to treat hyperlipidemia and hypertension. There are no significant drug interactions with omega-3 fatty acids. The American Heart Association recommends consumption of two servings of fish per week for persons with no history of coronary heart disease and at least one serving of fish daily for those with known coronary heart disease. Approximately 1 g/day of eicosapentaenoic acid plus docosahexaenoic acid is recommended for cardio protection. Higher dosages of omega-3 fatty acids are required to reduce elevated triglyceride levels (2-4 g/day). Modest decreases in blood pressure occur with significantly higher dosages of omega-3 fatty acids.

  20. Fritura de filetes de sardinas congeladas en aceite de oliva. Influencia de diferentes métodos de descongelación sobre el contenido graso y la composición en ácidos grasos

    Directory of Open Access Journals (Sweden)

    Álvsarez-Pontes, M. E.

    1994-06-01

    Full Text Available To study the effect of freezing and different thawing methods on the moisture, fat an fatty acid content of fried sardines, fresh sardine fillets were first frozen and then some were thawed either in a refrigerator at 4°C or in a microwave over prior to frying. These fillets were then analyzed both before and after being fried in olive oil. Frying increased the fat content of the fillets, mainly due to water losses, especially in those thawed in the refrigerator. Mono-unsaturated fatty acid (MUFA content increased in fresh and frozen fillets after frying from 21% to 55% and 56%, respectively. However, thawing prior to frying had a different effect depending on the method because oleic acid absorption was facilitated by refrigerator-thawing, the MUFA content increased to 61,8%, whereas after microwave-thawing the MUFA content reached 47%. Saturated and polyunsaturated fatty acids decreased in fried fillets compared to uncooked ones as a consequence of the increase in MUFA. Frying decreased the C22:6/C16:0 ratio with respect to fresh fillets in frozen fillets and in those thawed in the refrigerator but not in those thawed in a microwave.

    Filetes de sardinas frescas, congeladas y descongeladas en frigorífico a 4°C o en microondas se analizaron en crudo y después de freírlos en aceite de oliva, con objeto de conocer si la congelación y descongelación, previa a la fritura, alteraba los cambios en humedad, grasa y composición en ácidos grasos que introdujera la fritura. El contenido graso (g/100g de filetes de sardinas se incrementó durante el proceso de fritura, debido, sobre todo, a las pérdidas de agua. Dicho efecto aumentó principalmente en la descongelación en frigorífico. Con la fritura, la sardina fresca y la congelada sin previa descongelación se enriquecieron en ácido oleico, ascendiendo el contenido de ácidos grasos monoinsaturados en (AGM del 21 al 55-56%. La descongelación, anterior a la fritura, influyó de forma

  1. Omega-3 Index and Anti-Arrhythmic Potential of Omega-3 PUFAs.

    Science.gov (United States)

    Tribulova, Narcis; Szeiffova Bacova, Barbara; Egan Benova, Tamara; Knezl, Vladimir; Barancik, Miroslav; Slezak, Jan

    2017-10-30

    Omega-3 polyunsaturated fatty acids (PUFAs), namely eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are permanent subjects of interest in relation to the protection of cardiovascular health and the prevention of the incidence of both ventricular and atrial arrhythmias. The purpose of this updated review is to focus on the novel cellular and molecular effects of omega-3 PUFAs, in the context of the mechanisms and factors involved in the development of cardiac arrhythmias; to provide results of the most recent studies on the omega-3 PUFA anti-arrhythmic efficacy and to discuss the lack of the benefit in relation to omega-3 PUFA status. The evidence is in the favor of omega-3 PUFA acute and long-term treatment, perhaps with mitochondria-targeted antioxidants. However, for a more objective evaluation of the anti-arrhythmic potential of omega-3 PUFAs in clinical trials, it is necessary to monitor the basal pre-interventional omega-3 status of individuals, i.e., red blood cell content, omega-3 index and free plasma levels. In the view of evidence-based medicine, it seems to be crucial to aim to establish new approaches in the prevention of cardiac arrhythmias and associated morbidity and mortality that comes with these conditions.

  2. Measurements of B meson decays to (omega)K* and (omega)(rho)

    Energy Technology Data Exchange (ETDEWEB)

    Aubert, B; Cheng, C H; Lange, D J; Simani, M C; . Wright, D M; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R H; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Y G; Kukartsev, G; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Ronan, M T; Wenzel, W A; Abe, T; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmueller, O L; Claus, R; Convery, M R; Cristinziani, M; De Nardo, G; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W; Fan, S; Field, R C; Glanzman, T; Gowdy, S J; Hadig, T; Halyo, V; Hast, C; Hryn' ova, T; Innes, W R; Kelsey, M H; Kim, P; Kocian, M L; Keith, D W . S; Libby, J; Luitz, S; Luth, V; Lynch, H L; Marsiske, H; Messner, R; Muller, D R; O' Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Snyder, A; Soha, A; Stelzer, H; Strube, J; Su, D; Sullivan, M K; Va' vra, J; Wagner, S R; Weaver, M; Wisniewski, W J; Wittgen, M; Wright, D H; Yarritu, A K; Young, C C; Collaboration, B

    2006-03-14

    The authors describe searches for B meson decays to the charmless vector-vector final states {omega}K* and {omega}{rho} in 89 million B{bar B} pairs produced in e{sup +}e{sup -} annihilation at {radical}s = 10.58 GeV.

  3. Measurements of B Meson Decays to omega K* and omega rho

    Energy Technology Data Exchange (ETDEWEB)

    Aubert, B.

    2005-02-14

    We describe searches for B meson decays to the charmless vector-vector final states {omega}K* and {omega}{rho} in 89 million B{bar B} pairs produced in e{sup +}e{sup -} annihilation at {radical}s = 10.58 GeV.

  4. Las dietas suplementadas con ácidos grasos poliinsaturados n-3 mejoran el desarrollo fetoplacentario de las conejas

    OpenAIRE

    Rodríguez, M; López Tello, J.; Formoso Rafferty, Nora; García García, R. M.; Arias Álvarez, M.; Lorenzo, P.L. (Pedro); Garcia Rebollar, Pilar

    2015-01-01

    Un total de 74 conejas nulíparas de 8 semanas de edad se distribuyeron al azar en dos grupos desde la recría hasta el primer parto. Se alimentaron con dos piensos isofibrosos, isoenergéticos e isoproteicos formulados con dos fuentes de grasa diferentes: manteca (grupo Control, n=34) y un suplemento a base de aceite de salmón rico en ácidos grasos poliinsatura-dos (AGPI) n-3 (grupo AGPI, n= 34) con un nivel de inclusión del 6% (30 g/kg). Durante la recría recibieron 130 g/día y 10 días ante...

  5. Consumo de ácidos grasos trans y riesgo cardiovascular Consumption of trans fatty acids and cardiovascular risk

    Directory of Open Access Journals (Sweden)

    Fernando Manzur J

    2009-06-01

    Full Text Available Los ácidos grasos con configuración trans poco se encuentran en los alimentos de manera natural, sino que se incorporan a éstos como consecuencia de modificaciones principalmente debidas a los procesos industriales de hidrogenación a que se someten los aceites para convertirlos en grasas sólidas. Aún cuando su estructura incluye dobles enlaces, el tipo de configuración permite un comportamiento biológico similar al de los ácidos grasos saturados, con efectos negativos sobre múltiples funciones celulares. La evidencia demuestra que son perjudiciales para la salud, en especial a lo que se refiere a riesgo de enfermedad cardiovascular, razón por la cual es importante disminuir su consumo. Teniendo en consideración la evidencia obtenida de investigaciones sobre las alteraciones del metabolismo producidas por los ácidos grasos trans, es posible plantear una precaución lógica hacia el consumo de dietas ricas en dichos ácidos. Sus efectos deletéreos serían incluso peores en aquellas poblaciones que consumen bajas cantidades de ácidos grasos esenciales. De ahí surge la importancia de iniciar con prontitud políticas sanitarias orientadas a controlar la aterosclerosis en nuestro país. Las mismas deben estar necesariamente sustentadas sobre un conocimiento profundo de las características o condiciones particulares a las que nuestra población se encuentra sometida. Sólo así podrá darse inicio a una intervención efectiva sobre nuestros cuestionados hábitos alimentarios.Trans fatty acids are scarcely found naturally in food; they are incorporated to it as a result of modifications mainly due to hydrogenation industrial processes to which oils are submitted in order to obtain solid fats. Even when its structure includes double bonds, the type of configuration allows a biological behavior similar to that of saturated fatty acids, with negative effects on multiple cellular functions. The evidence shows that they are harmful to health

  6. OMEGA-3 POLYUNSATURATED FATTY ACIDS AND COGNITIVE DEVELOPMENT OF CHILDREN

    Directory of Open Access Journals (Sweden)

    O. A. Gromova

    2011-01-01

    Full Text Available Omega-3 polyunsaturated fatty acids (PUFA are important nutrient for proper support of normal living. Omega-3 PUFA play significant role in neurogenesis, neurotransmission, neuroprotection, they are necessary for development of human’s brain. Present study discusses results of fundamental and clinical studies on role of omega-3 PUFA in ontogenesis. Authors performed systematic analysis of physiological effects of omega-3 PUFA on molecular level. Deficiency of omega-3 PUFA results in decrease of intellect and increase of hyperactivity in children. The necessity of proper administration of omega-3 PUFA in early pre-school period and in younger schoolchildren is confirmed by results of clinical studies.

  7. Aceites vegetales sobre ácidos grasos y producción de metano in vitro en vacas lecheras.

    Directory of Open Access Journals (Sweden)

    Esperanza Prieto-Manrique

    2016-12-01

    Full Text Available El objetivo de este trabajo fue evaluar el efecto de la adición de aceites vegetales en dietas representativas de vacas lecheras bajo pastoreo, sobre los ácidos grasos, fermentación ruminal y producción de metano in vitro. La investigación se desarrolló en el laboratorio NUTRILAB–GRICA, perteneciente a la Facultad de Ciencias Agrarias, Universidad de Antioquia, Medellín, Colombia, en agosto del 2013. Se utilizó la técnica de producción de gas in vitro. En cuatro dietas (dos de monocultivo en Cynodon plectostachyus y dos de sistema silvopastoril intensivo con Leucaena leucocephala, se evaluó la adición de tres aceites vegetales (girasol, lino y palma a nivel del 2 y 4% de la MS, en un diseño completamente al azar con arreglo factorial de 4x3x2. En todas las dietas, la suplementación con aceite de girasol aumentó el contenido de ácido linoleico (C18:2 c9,12, ácido linoleico conjugado (ALC-c9t11 y ácido transvaccénico (ATV, C18:1 t11 después de la fermentación (p0,05. Ningún aceite afectó la cinética de fermentación, pH, total de ácidos grasos volátiles (AGV, proporción de AGV, ni la producción de metano.

  8. Ácidos grasos y parámetros de calidad del aceite de semilla de uva silvestre (Vitis spp.

    Directory of Open Access Journals (Sweden)

    O. Franco-Mora

    2015-01-01

    Full Text Available México es centro de origen de varias especies de Vitis. La gran mayoría de ellas no son empleadas en la agricultura e industrias derivadas. Como parte de la exploración de su potencial agroindustrial se identificó y cuantificó a los ácidos grasos del aceite de semilla de vid silvestre (Vitis spp. de frutos de Temascaltepec, México y de la accesión E-201, cultivada en Zumpahuacán, México. El contenido promedio de aceite en la semilla fue de 16,7%, encontrando ácido linoleico (71,5%, oleico (17,2%, palmítico (6,6% y esteárico (4,3%. En el aceite obtenido en vides de Temascaltepec se determinó índice de yodo (57,9 g/100 g, índice de saponificación (170,7 mg/g e índice de peroxidos (30 mEq/kg, valores relacionados posiblemente al contenido de ácidos grasos insaturados. Sin embargo, ese mismo grado de insaturación no concordó con el punto de humeo observado (211 °C, lo cual posiblemente está relacionado con el contenido de ácidos palmítico y esteárico. El aceite de semilla de vid silvestre cumple parcialmente con los estándares establecidos para el aceite de semilla de V. vinifera, lo cual implica su potencial culinario, agroindustrial y cosmetológico.

  9. Composición de ácidos grasos en ovas de trucha arco iris (Oncorhynchus mykiss, Walbaum, 1792

    Directory of Open Access Journals (Sweden)

    Rafael Rosado Puccini

    2012-06-01

    Full Text Available En este artículo se analizan con parámetros de composición 58 puestas de trucha arcoiris obtenidas, manejadas y monitoreadas individualmente en desempeño desde la fertilización hasta finalizar la etapa de reabsorción de vesícula. Además de los valores reproductivos, el contenido de ácidos grasos en las ovas se determinó en fresco, mediante cromatografía de gases. En el perfil medio se destacan los ácidos palmítico (C16, oleico (C18:1n-9 y docosahexaenoico (C22:6n-3 como los más representativos, con casi el 60% del total y, en general, en concentraciones estables entre las hembras. Tanto para cada ácido determinado como para el conjunto de contenidos integrados de las series n-3 y n-6, y los colectivos de saturados (SAF, monoinsaturados (MUFA y poliinsaturados (PUFA, se define un patrón de composición similar al reportado para la especie en otros esquemas de manejo y bajo regímenes nutricionales variables. Se analizó la condición conservativa en la incorporación de ácidos grasos al huevo, y se discutió su utilidad como posibles definitorios de calidad, teniendo como referente la alta variabilidad registrada en la supervivencia al final del proceso de incubación.

  10. Time to Talk: Five Things to Know about Omega-3s for Heart Disease

    Science.gov (United States)

    ... 5 Things To Know About Omega-3s for Heart Disease Share: Omega-3 fatty acids are a group ... shows omega-3s have a protective effect against heart disease. Experts agree that fish rich in omega-3 ...

  11. A protective lipidomic biosignature associated with a balanced omega-6/omega-3 ratio in fat-1 transgenic mice.

    Directory of Open Access Journals (Sweden)

    Giuseppe Astarita

    Full Text Available A balanced omega-6/omega-3 polyunsaturated fatty acid (PUFA ratio has been linked to health benefits and the prevention of many chronic diseases. Current dietary intervention studies with different sources of omega-3 fatty acids (omega-3 lack appropriate control diets and carry many other confounding factors derived from genetic and environmental variability. In our study, we used the fat-1 transgenic mouse model as a proxy for long-term omega-3 supplementation to determine, in a well-controlled manner, the molecular phenotype associated with a balanced omega-6/omega-3 ratio. The fat-1 mouse can convert omega-6 to omega-3 PUFAs, which protect against a wide variety of diseases including chronic inflammatory diseases and cancer. Both wild-type (WT and fat-1 mice were subjected to an identical diet containing 10% corn oil, which has a high omega-6 content similar to that of the Western diet, for a six-month duration. We used a multi-platform lipidomic approach to compare the plasma lipidome between fat-1 and WT mice. In fat-1 mice, an unbiased profiling showed a significant increase in the levels of unesterified eicosapentaenoic acid (EPA, EPA-containing cholesteryl ester, and omega-3 lysophosphospholipids. The increase in omega-3 lipids is accompanied by a significant reduction in omega-6 unesterified docosapentaenoic acid (omega-6 DPA and DPA-containing cholesteryl ester as well as omega-6 phospholipids and triacylglycerides. Targeted lipidomics profiling highlighted a remarkable increase in EPA-derived diols and epoxides formed via the cytochrome P450 (CYP450 pathway in the plasma of fat-1 mice compared with WT mice. Integration of the results of untargeted and targeted analyses has identified a lipidomic biosignature that may underlie the healthful phenotype associated with a balanced omega-6/omega-3 ratio, and can potentially be used as a circulating biomarker for monitoring the health status and the efficacy of omega-3 intervention in humans.

  12. Análisis Proximal, Perfil de Ácidos Grasos de las Vísceras del Cuy (Cavia porcellus) y su Uso Potencial en Alimentación Animal

    National Research Council Canada - National Science Library

    C H Acosta; A S Parra; J J Andrade; M C Guerra

    2016-01-01

    ...) y de su harina mediante análisis proximal y el perfil de ácidos grasos mediante cromatografía de gases. Se compararon estos resultados con materias primas convencionales como la harina de pescado...

  13. Rare B Meson Decays With Omega Mesons

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Lei; /Colorado U.

    2006-04-24

    Rare charmless hadronic B decays are particularly interesting because of their importance in understanding the CP violation, which is essential to explain the matter-antimatter asymmetry in our universe, and of their roles in testing the ''effective'' theory of B physics. The study has been done with the BABAR experiment, which is mainly designed for the study of CP violation in the decays of neutral B mesons, and secondarily for rare processes that become accessible with the high luminosity of the PEP-II B Factory. In a sample of 89 million produced B{bar B} pairs on the BABAR experiment, we observed the decays B{sup 0} {yields} {omega}K{sup 0} and B{sup +} {yields} {omega}{rho}{sup +} for the first time, made more precise measurements for B{sup +} {yields} {omega}h{sup +} and reported tighter upper limits for B {yields} {omega}K* and B{sup 0} {yields} {omega}{rho}{sup 0}.

  14. First measurement of the Omega /sup -/ decay branching ratios

    CERN Document Server

    Bourquin, M; Chatelus, Y; Chollet, J C; Degré, A; Froidevaux, D; Fyfe, A R; Gaillard, J M; Gee, C N P; Gibson, W M; Igo-Kemenes, P; Jeffreys, P W; Merkel, B; Morand, R; Plothow, H; Repellin, J P; Saunders, B J; Sauvage, G; Schiby, B; Siebert, H W; Smith, V J; Streit, K P; Strub, R; Thresher, J J; Tovey, Stuart N

    1979-01-01

    In an experiment in the CERN-SPS charged-hyperon beam, the main Omega /sup -/ decay branching ratios have been measured to be Gamma ( Omega /sup -/ to Lambda K/sup -/)/ Gamma (all)=0.686+or-0.013, Gamma ( Omega /sup -/ to Xi /sup 0/ pi /sup -/)/ Gamma (all) =0.234+or-0.013, Gamma ( Omega /sup -/ to Xi /sup -/ pi /sup 0/)/ Gamma (all)=0.080+or-0.008. The relative branching ratio of the two Xi pi modes provides a test of the Delta I=1/2 rule in decuplet-octet transitions. A search has also been made for the rare decay modes Omega /sup -/ to Lambda pi /sup -/, Omega /sup -/ to Xi /sup -/ gamma , Omega /sup -/ to Xi /sup -/ pi /sup +/ pi /sup -/ and Omega /sup -/ to Xi /sup 0/e/sup -/ nu . (6 refs).

  15. Effects of Diets Enriched in Omega-9 or Omega-6 Fatty Acids on Reproductive Process

    Directory of Open Access Journals (Sweden)

    Seyedeh Neda Mousavi

    2016-08-01

    Full Text Available Objective: Maternal type and amounts of dietary fatty acids affect on reproductive process in the mice. The present study investigated the effects of maternal supplementation with different amounts of omega-6 or omega-9 during pregnancy on the number of offspring, sex-ratio and duration of gestation.Materials and methods: Eight-week-old female C57BL/6 mice were randomly assigned into four dietary groups including low omega-6 (16%; LO6, low omega-9 (16%; LO9, high omega-6 (45%; HO6 and high omega-9 (45%; HO9 during gestation. Number of offspring, sex-ratio and duration of pregnancy were compared among four dietary groups.Results: There was significant difference between LO6 and HO6 (p < 0.0001, LO9 and HO9 (p < 0.0001 groups in total number of pups. The number of female and male offspring were significantly different between LO6 and LO9 (p = 0.009 and p = 0.001, respectively, LO9 and HO9 (p = 0.01 and p = 0.025 groups. Duration of pregnancy was significantly higher in low fat diet than high fat diet groups (< 0.001.Conclusion: High fat diet reduced number of pups, gestation duration and lead to early labor. Omega-9 fatty acids shifted sex of offspring to females.

  16. Omega-3 fatty acids for cystic fibrosis.

    Science.gov (United States)

    Oliver, Colleen; Watson, Helen

    2016-01-05

    Studies suggest that a diet rich in omega-3 essential fatty acids may have beneficial anti-inflammatory effects for chronic conditions such as cystic fibrosis. This is an updated version of a previously published review. To determine whether there is evidence that omega-3 polyunsaturated fatty acid supplementation reduces morbidity and mortality and to identify any adverse events associated with supplementation. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group's Trials Register comprising references identified from comprehensive electronic database searches and handsearches of relevant journals and abstract books of conference proceedings. Authors and persons interested in the subject of the review were contacted.Date of last search: 13 August 2013. Randomised controlled trials in people with cystic fibrosis comparing omega-3 fatty acid supplements with placebo. Two authors independently selected studies for inclusion, extracted data and assessed the risk of bias of the studies. The searches identified 15 studies; four studies with 91 participants (children and adults) were included; duration of studies ranged from six weeks to six months. Two studies were judged to be at low risk of bias based on adequate randomisation but this was unclear in the other two studies. Three of the studies adequately blinded patients, however, the risk of bias was unclear in all studies with regards to allocation concealment and selective reporting.Two studies compared omega-3 fatty acids to olive oil for six weeks. One study compared a liquid dietary supplement containing omega-3 fatty acids to one without for six months. One study compared omega-3 fatty acids and omega-6 fatty acids to a control (capsules with customised fatty acid blends) for three months. Only one short-term study (19 participants) comparing omega-3 to placebo reported a significant improvement in lung function and Shwachman score and a reduction in sputum volume in the omega-3 group. Another

  17. OMEGA Supersonic Gas-Jet Target Characterization

    Science.gov (United States)

    Hansen, A.; Haberberger, D.; Shaw, J. L.; Froula, D. H.

    2017-10-01

    A supersonic gas-jet target system has been characterized using a Mach-Zehnder interferometer, allowing for the study of the gas dynamics during the opening and closing of the valve. Gas-jet targets provide uniform plasmas with flexibility in size and density while also offering excellent diagnostic access to the plasma. The gas jet is the first component in the development of a new laser-plasma interaction platform to be implemented on the OMEGA Laser System. The platform will use a tunable UV laser from OMEGA EP, known as the tunable OMEGA port 9 beam, to facilitate the study of cross-beam energy transfer and the associated mitigation strategies. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

  18. Motivational factors for consuming omega-3 PUFAs

    DEFF Research Database (Denmark)

    Krutulyte, Rasa; Grunert, Klaus G.; Scholderer, Joachim

    2008-01-01

    foods. This paper presents the results of a qualitative pilot study that aimed to explore Danish consumers' motives for choosing omega-3/fish oil enriched products. The Health Action Process Approach (HAPA) was applied as a theoretical framework to understand the process by which people choose healthy...... to the choice of omega-3/fish oil, whereas perception of omega-3 as an ingredient in selected foods does indeed influence consumers' choice of carrier-ingredient combinations.......Growing consumer awareness of functional foods and understanding of their positive nutritional effects have led to the need of specific studies and have captured more attention than ever before. In Europe, Danish consumers have been found to be relatively negative towards the concept of functional...

  19. Gouy Interferometry: Properties of Multicomponent System Omega Graphs

    Energy Technology Data Exchange (ETDEWEB)

    Miller, D G

    2007-01-24

    We consider the properties of {Omega} graphs ({Omega} vs f(z)) obtained from Gouy interferometry on multicomponent systems with constant diffusion coefficients. We show that they must have (a) either a maximum or else a minimum between f(z)=0 and f(z)=1 and (b) an inflection point between the f(z) value at the extremum and f(z)=1. Consequently, an {Omega} graph cannot have both positive and negative {Omega} values.

  20. Dietary omega-3 fatty acids for women.

    Science.gov (United States)

    Bourre, Jean-Marie

    2007-01-01

    This review details the specific needs of women for omega-3 fatty acids, including alpha linoleic acid (ALA) and the very long chain fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Omega-3 fatty acid (dietary or in capsules) ensures that a woman's adipose tissue contains a reserve of these fatty acids for the developing fetus and the breast-fed newborn infant. This ensures the optimal cerebral and cognitive development of the infant. The presence of large quantities of EPA and DHA in the diet slightly lengthens pregnancy, and improves its quality. Human milk contains both ALA and DHA, unlike that of other mammals. Conditions such as diabetes can alter the fatty acid profile of mother's milk, while certain diets, like those of vegetarians, vegans, or even macrobiotic diets, can have the same effect, if they do not include seafood. ALA, DHA and EPA, are important for preventing ischemic cardiovascular disease in women of all ages. Omega-3 fatty acids can help to prevent the development of certain cancers, particularly those of the breast and colon, and possibly of the uterus and the skin, and are likely to reduce the risk of postpartum depression, manic-depressive psychosis, dementias (Alzheimer's disease and others), hypertension, toxemia, diabetes and, to a certain extend, age-related macular degeneration. Omega-3 fatty acids could play a positive role in the prevention of menstrual syndrome and postmenopausal hot flushes. The normal western diet contains little ALA (less than 50% of the RDA). The only adequate sources are rapeseed oil (canola), walnuts and so-called "omega-3" eggs (similar to wild-type or Cretan eggs). The amounts of EPA and DHA in the diet vary greatly from person to person. The only good sources are fish and seafood, together with "omega-3" eggs.

  1. Developmentally dependent and different roles of fatty acids OMEGA-6 and OMEGA-3

    DEFF Research Database (Denmark)

    Mourek, J; Mourek, J

    2011-01-01

    The developmentally-dependent differences in the biological significances and effects of PUFA-OMEGA-6 (namely of arachidonic acid) and PUFA-OMEGA-3 (namely of docosahexaenoic acid) are discussed. The clinical results as well as developmental experiences are indicating a hypothesis of the evolution...... that created mutual relationship between those two substances (with immunological basis and following recuperation). The anti-inflammatory actions of PUFA-OMEGA-3 are the most visible (and significant) contrasts as compared with the large affects of namely arachidonic acid and its metabolites....

  2. Hierarchical Analysis of the Omega Ontology

    Energy Technology Data Exchange (ETDEWEB)

    Joslyn, Cliff A.; Paulson, Patrick R.

    2009-12-01

    Initial delivery for mathematical analysis of the Omega Ontology. We provide an analysis of the hierarchical structure of a version of the Omega Ontology currently in use within the US Government. After providing an initial statistical analysis of the distribution of all link types in the ontology, we then provide a detailed order theoretical analysis of each of the four main hierarchical links present. This order theoretical analysis includes the distribution of components and their properties, their parent/child and multiple inheritance structure, and the distribution of their vertical ranks.

  3. Estudio analítico de la composición en ácidos grasos de mostaza y salsas de mostaza.

    Directory of Open Access Journals (Sweden)

    López Argüello, E.

    1999-12-01

    Full Text Available In order to characterise mustard (whole seed or flour, mustard sauces with grain and mustard sauces in relation to their base seed, the concentrations of fatty acid were determinated by gas chromatography (GC. Erucic acid was the most abundant fatty acid component in mustard and mustard sauces (27,7 % and 24,6 % of total fatty acid content, followed by oleic acid (20,0 % and 21,1 % and linolenic acid (16,3 % and 16.2%. The major acid in mustard sauces with grain was linolenic (21,4 %, followed by linoleic acid (20,3 % and oleic acid (19,3 %. By means of correlation and discriminant analysis the samples have been grouped and classified. It is shown that fatty acid are usefull parameters for quality control analysis of mustard sauces.

    Se determinaron, por cromatografía gaseosa, el perfil de los ácidos grasos en mostaza (semilla y harina, salsas de mostaza con grano y salsas finas de mostaza con el objeto de caracterizarlas en relación con la semilla base. El ácido erúcico fue el más abundante en la mostaza y en las salsas finas (27,7 % y 24,6 % del contenido total de ácidos grasos, seguido de los ácidos oleico (20,0 % y 21,1 % y linoleico (16,3 y 16.2 %. En las salsas de mostaza con grano el ácido graso mayoritario fue el linolénico (21,4 % seguido de los ácidos linoleico (20,3 % y oleico (19,3 %. Mediante los análisis de correlación y discriminante las muestras son agrupadas y clasificadas. Los ácidos grasos han demostrado ser parámetros válidos para el análisis del control de calidad de las salsas de mostaza.

  4. Omega-3 and omega-6 content of medicinal foods for depressed patients: implications from the Iranian Traditional Medicine

    NARCIS (Netherlands)

    Tavakkoli-Kakhki, Mandana; Motavasselian, Malihe; Mosaddegh, Mahmoud; Esfahani, Mohammad Mahdi; Kamalinejad, Mohammad; Nematy, Mohsen; Eslami, Saeid

    2014-01-01

    Considering the increasing prevalence of depression in modern societies and the positive effects of omega-3 polyunsaturated fatty acids on depression, this study aims to investigate the omega-3 and omega-6 content of various foodstuffs, prescribed or prohibited by Iranian Traditional Medicine (ITM).

  5. Evolución del contenido de ácidos grasos de aceite de aguacate durante la maduración

    Directory of Open Access Journals (Sweden)

    Martín Nieto, L.

    1995-04-01

    Full Text Available The minimum fat richness of avocados necessary for marketing of the fruit is 8%, although after vegetative maturation values of about 20% or more are reached, the values depending on the variety. In the period between harvesting, when commercial maturity is reached, and full maturation, not only is the fat content increased but changes also occur in the fat composition, the unsaturated fatty acids increasing while the amount of saturated fatty acids decreases.

    La riqueza grasa mínima exigida al aguacate para su salida al mercado es del 8%, aunque en la maduración vegetativa se alcanzan valores de alrededor del 20% o más según variedades. En el período que transcurre desde el corte del fruto, de acuerdo con la madurez comercial, hasta la completa madurez del mismo no sólo aumenta la riqueza grasa, sino que se ha observado una evolución del contenido graso, de forma que hay un aumento de los ácidos grasos Insaturados en detrimento del contenido en ácidos grasos saturados.

  6. Contenidos de isómeros trans de los ácidos grasos en productos cárnicos, (II Tejido adiposo y grasa intramuscular del cerdo

    Directory of Open Access Journals (Sweden)

    Lluch, M. C.

    1993-04-01

    Full Text Available We give the results obtained for the determination of trans fatty acids in subcutaneous and intramuscular fats from different pork samples, using gas chromatography. Values obtained are low and similar in both kind of fats, with a mean value of 0.6% of C18:1 trans. A clear influence of animal feeding is detected due to the significant differences of this isomer content between samples from different origin. Also, correlations have been observed between C18:1 t. content and saturated, mono, polinsaturated fatty acids and fat intramuscular contents.

    Se presentan los resultados obtenidos en la determinación de ácidos grasos trans en una serie de muestras de tejidos subcutáneo y muscular, procedentes de canales de cerdo, mediante cromatografía en fase gaseosa. Ambos tipos de grasas presentan valores similares y relativamente bajos, con un valor medio del 0.6% de 018:1 t. Se detecta una marcada influencia de la alimentación, puesta de manifiesto por las diferencias significativas obtenidas para los contenidos de C18:1 trans, en función del origen de las muestras. Igualmente, se recogen las correlaciones obtenidas entre los contenidos de C18:1 t. y los de ácidos grasos saturados, monoinsaturados y poliinsaturados, así como con el contenido graso intramuscular.

  7. Role of diets rich in omega-3 and omega-6 in the development of cancer

    OpenAIRE

    Huerta-Yépez, Sara; Ana B. Tirado-Rodriguez; Hankinson, Oliver

    2016-01-01

    Over the past decade, some studies have addressed the therapeutic effects of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and the opposite effects of omega-6 (ω-6) PUFAs on several diseases, including cardiovascular disorders, diabetes, neurodegenerative diseases, and cancer. Research demonstrates the safety of these naturally occurring ingredients. Of particular interest, several studies have shown that ω-3 PUFAs possess a therapeutic role against certain types of cancer. It is also known...

  8. Omega-6 and omega-3 fatty acid nutrition amongst Malaysians are far from desirable

    OpenAIRE

    Tony Kock Wai Ng; Sivalingam Nalliah; Azlinda Hamid; Siew Rong Wong; Sim Ling Chee; Cheryl Andrea Augustine

    2012-01-01

    This paper reviews available reports on theomega-6 (linoleic acid, LA) and omega-3 fatty acid[alpha-linolenic acid (ALA) + eicosapentaenoic acid(EPA) + docosahexaenoic acid) intakes amongstMalaysians against Malaysian Recommended NutrientIntakes (RNI), focussing particularly on pregnant andlactating women because of the availability of data forthese latter vulnerable groups. Overall, the omega-6 andomega-3 fatty acid nutrition amongst Malaysians arepoor and far from desirable. The nutritional...

  9. Cerenkov counters at the Omega Facility

    CERN Multimedia

    1975-01-01

    P. Petroff on the left. Here one sees both the gas Cerenkov counters sitting in front of the magnet to select forward emitted particles. The smaller one, working at high pressure, sits nearest to the Omega magnet (see photo 7505073X), the other (see photo 7505071X) works at atmospheric pressure.

  10. Faint stars and OmegaCAM

    NARCIS (Netherlands)

    Kuijken, K; Cristiani, S; Renzini, A; Williams, RE

    2001-01-01

    OmegaCAM will be the wide-field imager on the VLT Survey Telescope. In this contribution I present applications of this instrument to the study of faint stellar populations. Two projects are highlighted: a proper motion study to uncover the galactic halo population, and a microlensing study towards

  11. Omega-3 Index and Cardiovascular Health

    Directory of Open Access Journals (Sweden)

    Clemens von Schacky

    2014-02-01

    Full Text Available Recent large trials with eicosapentaenoic acid (EPA and docosahexaenoic acid (DHA in the cardiovascular field did not demonstrate a beneficial effect in terms of reductions of clinical endpoints like total mortality, sudden cardiac arrest or other major adverse cardiac events. Pertinent guidelines do not uniformly recommend EPA + DHA for cardiac patients. In contrast, in epidemiologic findings, higher blood levels of EPA + DHA were consistently associated with a lower risk for the endpoints mentioned. Because of low biological and analytical variability, a standardized analytical procedure, a large database and for other reasons, blood levels of EPA + DHA are frequently assessed in erythrocytes, using the HS-Omega-3 Index® methodology. A low Omega-3 Index fulfills the current criteria for a novel cardiovascular risk factor. Neutral results of intervention trials can be explained by issues of bioavailability and trial design that surfaced after the trials were initiated. In the future, incorporating the Omega-3 Index into trial designs by recruiting participants with a low Omega-3 Index and treating them within a pre-specified target range (e.g., 8%–11%, will make more efficient trials possible and provide clearer answers to the questions asked than previously possible.

  12. Coefficient Omega Bootstrap Confidence Intervals: Nonnormal Distributions

    Science.gov (United States)

    Padilla, Miguel A.; Divers, Jasmin

    2013-01-01

    The performance of the normal theory bootstrap (NTB), the percentile bootstrap (PB), and the bias-corrected and accelerated (BCa) bootstrap confidence intervals (CIs) for coefficient omega was assessed through a Monte Carlo simulation under conditions not previously investigated. Of particular interests were nonnormal Likert-type and binary items.…

  13. Reconstrucción autóloga de mama con colgajo de latissimus dorsiy microinjerto graso

    Directory of Open Access Journals (Sweden)

    Jorge-Luis Marcos-Quispe

    Full Text Available Resumen Antecedentes y Objetivo En reconstrucción mamaria existen diversas técnicas quirúrgicas basadas en el uso de colgajos y/o implantes, que se utilizan según la particularidad de cada caso. En nuestra práctica, preferimos aquellas que utilizan solo tejidos autólogos porque ofrecen, a nuestro juicio, mayores ventajas. Presentamos una alternativa de reconstrucción mamaria total utilizando solo tejidos autólogos; esta técnica fusiona el colgajo miocutáneo de latissimus dorsi con la técnica de micro injerto graso que proporciona relleno autólogo, evitando así el uso de prótesis. Material y Método Incluimos en el estudio a todas las pacientes con mastectomía radical modificada que aceptaron y concluyeron su reconstrucción mamaria diferida con la técnica propuesta, entre enero del 2011 y junio del 2015, en el Servicio de Cirugía Plástica y Quemados del Hospital Nacional Guillermo Almenara (Lima, Perú. Resultados Se realizó este tipo de reconstrucción en 24 pacientes; el volumen total lipoinjertado fue de 380 a 780 cc (media de 525 cc en 1 a 4 sesiones quirúrgicas. Se inició con el colgajo y la primera sesión de microinjerto graso intraoperatorio, aplicando entre 260 a 400 cc (media de 332 cc en todos los tejidos expuestos. El 80% de este volumen inicial se inyectó en el colgajo miocutáneo, evidenciándose clínicamente un alto grado de prendimiento.En el 45.8%de los casos fue necesaria la desepitelización de la isla cutánea y en el 37.5% se realizaron colgajos de transposición en la zona lateral de la mama. Todos los resultados fueron satisfactorios y las complicaciones fueron menores. Conclusiones Consideramos esta técnica como una buena alternativa, segura y versátil, para la reconstrucción mamaria total con tejidos autólogos, con ventajas a corto y largo plazo.

  14. Omega-3 Fatty Acids in the Management of Epilepsy.

    Science.gov (United States)

    Tejada, Silvia; Martorell, Miquel; Capó, Xavier; Tur, Josep A; Pons, Antoni; Sureda, Antoni

    2016-01-01

    Omega-3 and omega-6 fatty acids are polyunsaturated fatty acids (PUFAs) with multiple double bonds. Linolenic and alpha-linolenic acids are omega-6 and omega-3 PUFAs, precursors for the synthesis of long-chain PUFAs (LC-PUFAs), such as arachidonic acid (omega-6 PUFA), and eicosapentaenoic and docosahexaenoic acids (omega-3 PUFAs). The three most important omega-3 fatty acids are alpha-linolenic, eicosapentaenoic and docosahexaenoic acids, which cannot be synthesized in enough amounts by the body, and therefore they must be supplied by the diet. Omega-3 fatty acids are essential for the correct functioning of the organism and participate in many physiological processes in the brain. Epilepsy is a common and heterogeneous chronic brain disorder characterized by recurrent epileptic seizures leading to neuropsychiatric disabilities. The prevalence of epilepsy is high achieving about 1% of the general population. There is evidence suggesting that omega-3 fatty acids may have neuroprotective and anticonvulsant effects and, accordingly, may have a potential use in the treatment of epilepsy. In the present review, the potential use of omega-3 fatty acids in the treatment of epilepsy, and the possible proposed mechanisms of action are discussed. The present article summarizes the recent knowledge of the potential protective role of dietary omega-3 fatty acids in epilepsy.

  15. Omega-3 fatty acids and cardiovascular risk.

    Science.gov (United States)

    Kruse, Leslie G; Ogletree, Richard L

    2013-06-01

    Omega-3 polyunsaturated fatty acids (PUFA's) have an FDA indication for triglyceride lowering in patients with hypertriglyceridemia. Some European agencies have also approved omega-3 fatty acids for cardiovascular risk modification. Several major societies in the US also recommend their use following myocardial infarction. The purpose of this review was to assimilate available evidence from randomized controlled trials into one systematic review to determine the association between omega-3 fatty acids and cardiovascular outcomes. Systematic review of randomized, controlled trials with meta-analysis PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials (up to August 2012) were searched using a predefined algorithm. All randomized trials evaluating omega-3 polyunsaturated fatty acid supplementation in adults were considered. Trials selected were all randomized, controlled against another diet or placebo, and implemented in primary or secondary cardiovascular disease (CVD) prevention settings. Trials with duration less than 1 year were excluded. Outcomes eligible for review included all-cause mortality, cardiac death, sudden death, MI, and all types of stroke. Fatty acids could be given through diet or through supplements. Additionally, references listed in reviews were screened. Two investigators independently extracted data. Another investigator resolved discrepancies. After retrieving 3,625 citations, 20 studies involving 68,680 participants were included. Two trials used dietary counseling to provide omega-3 fatty acids. The rest used supplements. In the 2 trials using dietary fatty acids, all-cause mortality and cardiac death were assessed and showed associations in opposite directions; therefore, with these discrepancies, quantitative synthesis of these trials was not performed.

  16. Production and Decay of Omega_c^0

    CERN Document Server

    Aubert, B; Abrams, G S; Adye, T; Ahmed, S; Alam, M S; Albert, J; Aleksan, R; Allen, M T; Allison, J; Altenburg, D D; Anderson, J; Andreotti, M; Angelini, C; Anulli, F; Arnaud, N; Asgeirsson, D J; Aston, D; Azzolini, V; Baak, M A; Back, J J; Baldini-Ferroli, R; Band, H R; Banerjee, Sw; Baracchini, E; Bard, D J; Barlow, N R; Barlow, R J; Bartoldus, R; Batignani, G; Battaglia, M; Bauer, J M; Bechtle, P; Beck, T W; Behera, P K; Bellini, F; Ben-Haim, E; Benelli, G; Bequilleux, J; Berger, N; Bernard, D; Berryhill, J W; Bettarini, S; Bettoni, D; Bevan, A J; Bhuyan, B; Bianchi, F; Biasini, M; Biesiada, J; Blanc, F; Blaylock, G; Blinov, V E; Bloom, P C; Blount, N L; Bomben, M; Bondioli, M; Bonneaud, G R; Bosisio, L; Boutigny, D; Bozzi, C; Brandt, T; Brau, J E; Briand, H; Brown, D N; Brunet, S; Buchanan, C; Bugg, W; Bukin, A D; Bula, R; Burchat, P R; Button-Shafer, J; Buzzo, A; Bóna, M; Cahn, R N; Calabrese, R; Calcaterra, A; Calderini, G; Campagnari, C; Carpinelli, M; Cartaro, C; Castelli, G; Cavoto, G; Cecchi, A; Cenci, R; Cervelli, A; Chai, X; Chaisanguanthum, K S; Charles, M J; Chauveau, J; Chavez, C A; Chen, C; Chen, E; Chen, S; Chen, X; Chen, X R; Cheng, C H; Chia, Y M; Cibinetto, G; Clark, P J; Claus, R; Cochran, J; Coleman, J P; Contri, R; Convery, M R; Corwin, L A; Cossutti, F; Cottingham, W N; Covarelli, R; Cowan, G; Cowan, R; Crawley, H B; Cremaldi, L; Cunha, A; Curry, S; Côté, D; D'Orazio, A; Dahmes, B; Dallapiccola, C; Dasu, S; Dauncey, P D; David, P; Davier, M; Davis, C L; De Nardo, Gallieno; De Sangro, R; Del Amo-Sánchez, P; Del Buono, L; Del Re, D; Della Ricca, G; Denig, A G; Di Lodovico, F; Di Marco, E; Dingfelder, J C; Dong, L; Dorfan, J; Druzhinin, V P; Dubitzky, R S; Dubois-Felsmann, G P; Dujmic, D; Dunwoodie, W; Dvoretskii, A; Ebert, M; Eckmann, R; Edgar, C L; Edwards, A J; Eigen, G; Eisner, A M; Elmer, P; Emery, S; Ernst, J A; Escalier, M; Eschenburg, V; Eschrich, I; Eyges, V; Fabozzi, F; Faccini, R; Fang, F; Feltresi, E; Ferrarotto, F; Ferroni, F; Field, R C; Finocchiaro, G; Fisher, P H; Flacco, C J; Flack, R L; Flächer, H U; Flood, K T; Ford, W T; Forster, I J; Forti, F; Foulkes, S D; Franchini, P; Franek, B; Frey, R; Fritsch, M; Fry, J R; Fulsom, B G; Gabareen, A M; Gabathuler, E; Gagliardi, N; Gaidot, A; Gallo, F; Gamba, D; Gamet, R; Gan, K K; Ganzhur, S F; Garra Tico, J; Gary, J W; Gaspero, M; Gaz, A; George, K A; Giorgi, M A; Gladney, L; Glanzman, T; Godang, R; Golubev, V B; Gowdy, S J; Gradl, W; Graham, M T; Graugès-Pous, E; Grenier, P; Gritsan, A V; Grosdidier, G; Groysman, Y; Guo, Z J; Haire, M; Hamano, K; Hamel de Monchenault, G; Hamon, O; Harrison, P F; Hartfiel, B L; Hast, C; Hauke, A; Hawkes, C M; Hearty, C; Held, T; Hertzbach, S S; Heusch, C A; Hirschauer, J F; Hitlin, D G; Hollar, J J; Hong, T M; Honscheid, K; Hopkins, D A; Hrynóva, T; Hufnagel, D; Hutchcroft, D E; Höcker, A; Igonkina, O; Innes, W R; Izen, J M; Jackson, P D; Jackson, P S; Jacobsen, R G; Jain, V; Jasper, H; Jawahery, A; Jessop, C P; Kadyk, J A; Kagan, H; Karyotakis, Yu; Kass, R; Kelsey, M H; Kerth, L T; Khan, A; Kim, H; Kim, P; Kirkby, D; Klose, V; Knecht, N S; Koch, H; Kolb, J A; Kolomensky, Yu G; Kovalskyi, D; Kowalewski, R V; Kozanecki, W; Kreisel, A; Krishnamurthy, M; Kroeger, R; Kroseberg, J; Kukartsev, G; Kutter, P E; La Vaissière, C de; Lacker, H M; Lae, C K; Lafferty, G D; Lanceri, L; Lange, D J; Lankford, A J; Latham, T E; Latour, E; Lau, Y P; Lazzaro, A; Le Diberder, F R; Lees, J P; Legendre, M; Leith, D W G S; Lepeltier, V; Leruste, P; Lewandowski, B; Li Gioi, L; Li, S; Li, X; Lista, L; Liu, F; Liu, H; Lo Vetere, M; LoSecco, J M; Lockman, W S; Lombardo, V; Long, O; Lopes-Pegna, D; Lopez-March, N; Lou, X C; Lu, M; Luitz, S; Lund, P; Luppi, E; Lusiani, A; Lutz, A M; Lynch, G; Lynch, H L; López, L; Lü, C; Lüth, V; MacFarlane, D B; Macri, M M; Mader, W F; Majewski, S A; Malcles, J; Mallik, U; Mancinelli, G; Mandelkern, M A; Manoni, E; Marchiori, G; Margoni, M; Marks, J; Marsiske, H; Martin, E C; Martínez-Vidal, F; Mattison, T S; Mazur, M A; Mazzoni, M A; McKenna, J A; McMahon, T R; Mclachlin, S E; Meadows, B T; Menges, W; Merkel, J; Messner, R; Meyer, N T; Meyer, W T; Milanes, D A; Mir, L M; Mishra, K; Mohanty, G B; Monge, M R; Monorchio, D; Moore, T B; Morandin, M; Morganti, M; Morganti, S; Morii, M; Morris, J P; Muheim, F; Müller, D R; Nagel, M; Narsky, I; Nash, J A; Nauenberg, U; Neal, H; Negrini, M; Neri, N; Nicholson, H; Nikolich, M B; Nogowski, R; Nugent, I M; O'Grady, C P; Ocariz, J; Ofte, I; Olaiya, E O; Olivas, A; Olsen, J; Onuchin, A P; Orimoto, T J; Oyanguren, A; Paar, H P; Pacetti, S; Palano, A; Palombo, F; Pan, B; Pan, Y; Panduro-Vazquez, W; Paoloni, E; Pappagallo, M; Park, W; Passaggio, S; Patel, P M; Patrignani, C; Patteri, P; Payne, D J; Pelizaeus, M; Pelliccioni, M; Perazzo, A; Perl, M; Peruzzi, I M; Petersen, B A; Petrella, A; Petzold, A; Piatenko, T; Piccolo, M; Piemontese, L; Pierini, M; Piredda, G; Playfer, S; Poireau, V; Polci, F; Pompili, A; Porter, F C; Posocco, M; Prell, S; Prencipe, E; Prepost, R; Pripstein, M; Prudent, X; Pruvot, S; Pulliam, T; Purohit, M V; Pérez, A; Rahatlou, S; Rahimi, A M; Rahmat, R; Rama, M; Ratcliff, B N; Raven, G; Regensburger, J J; Renga, F; Ricciardi, S; Richman, J D; Ritchie, J L; Rizzo, G; Roberts, D A; Robertson, A I; Robertson, S H; Robutti, E; Rodier, S; Roe, N A; Ronan, M T; Roney, J M; Roodman, A; Rosenberg, E I; Rotondo, M; Roudeau, P; Rubin, A E; Ruland, A M; Röthel, W; Sacco, R; Saeed, M A; Saleem, M; Salnikov, A A; Salvati, E; Salvatore, F; Sanders, D A; Santoro, V; Santroni, A; Saremi, S; Schalk, T; Schenk, S; Schilling, C J; Schindler, R H; Schofield, K C; Schott, G; Schröder, T; Schröder, H; Schubert, J; Schubert, K R; Schumm, B A; Schune, M H; Schwiening, J; Schwierz, R; Schwitters, R F; Sciacca, C; Sciolla, G; Seiden, A; Sekula, S J; Serednyakov, S I; Serrano, J; Sharma, V; Shen, B C; Simard, M; Simi, G; Simonetto, F; Sinev, N B; Skovpen, Yu I; Smith, A J S; Smith, J G; Snoek, H L; Snyder, A; Sobie, R J; Soffer, A; Sokoloff, M D; Solodov, E P; Sordini, V; Spaan, B; Spanier, S M; Spitznagel, M; Steinke, M; Stelzer, J; Stocchi, A; Stoker, D P; Stroili, R; Strom, D; Strube, J; Stugu, B; Su, D; Sullivan, M K; Summers, D J; Sun, L; Sundermann, J E; Suzuki, K; Swain, S K; Tackmann, K; Taras, P; Taylor, F; Telnov, A V; Teodorescu, L; Ter-Antonian, R; Thiebaux, C; Thompson, J M; Tisserand, V; Todyshev, K Yu; Toki, W H; Torrence, E; Tosi, S; Touramanis, C; Tuggle, J M; Ulmer, K A; Uwer, U; Van Bakel, N; Vasseur, G; Vavra, J; Verderi, M; Viaud, F B; Vitale, L; Voci, C; Voena, C; Volk, A; Wacker, K; Wagner, A P; Wagner, S R; Waldi, R; Walker, D; Walsh, J J; Wang, W F; Wappler, F R; Watson, A T; Weaver, M; Wenzel, W A; West, T J; Wilden, L; Williams, D C; Wilson, F F; Wilson, J R; Wilson, M G; Wilson, R J; Winklmeier, F; Winstrom, L O; Wisniewski, W J; Wittgen, M; Wong, Q K; Wormser, G; Wren, A C; Wright, D H; Wright, D M; Wu, J; Wu, S L; Xie, Y; Yamamoto, R K; Yarritu, A K; Ye, S; Yi, J I; Yi, K; Young, C C; Yu, Z; Yéche, C; Zain, S B; Zallo, A; Zeng, Q; Zghiche, A; Zhang, J; Zhang, L; Zhao, H W; Ziegler, V; Zito, M; Çuhadar-Dönszelmann, T; al, et

    2007-01-01

    We present an analysis of inclusive Omega_c^0 baryon production and decays in 230.5 fb^-1 of data recorded with the BABAR detector at the PEP-II asymmetric-energy e+ e- collider at the Stanford Linear Accelerator Center. Omega_c^0 baryons are reconstructed in four final states (Omega- pi+, Omega- pi+ pi0, Omega- pi+ pi+ pi-, Xi- K- pi+ pi+) and the ratios of branching fractions for these final states are measured. We also measure the momentum spectrum of the Omega_c^0 baryons in the e+ e- center-of-mass frame. From the spectrum, we observe Omega_c^0 production from B decays and in ccbar events, and extract the two rates of production.

  17. New insights into the health effects of dietary saturated and omega-6 and omega-3 polyunsaturated fatty acids.

    Science.gov (United States)

    de Lorgeril, Michel; Salen, Patricia

    2012-05-21

    Cardiovascular diseases and cancers are leading causes of morbidity and mortality. Reducing dietary saturated fat and replacing it with polyunsaturated fat is still the main dietary strategy to prevent cardiovascular diseases, although major flaws have been reported in the analyses supporting this approach. Recent studies introducing the concept of myocardial preconditioning have opened new avenues to understand the complex interplay between the various lipids and the risk of cardiovascular diseases. The optimal dietary fat profile includes a low intake of both saturated and omega-6 fatty acids and a moderate intake of omega-3 fatty acids. This profile is quite similar to the Mediterranean diet. On the other hand, recent studies have found a positive association between omega-6 and breast cancer risk. In contrast, omega-3 fatty acids do have anticancer properties. It has been shown that certain (Mediterranean) polyphenols significantly increase the endogenous synthesis of omega-3 whereas high intake of omega-6 decreases it. Finally, epidemiological studies suggest that a high omega-3 to omega-6 ratio may be the optimal strategy to decrease breast cancer risk. Thus, the present high intake of omega-6 in many countries is definitely not the optimal strategy to prevent cardiovascular disease and cancers. A moderate intake of plant and marine omega-3 in the context of the traditional Mediterranean diet (low in saturated and omega-6 fatty acids but high in plant monounsaturated fat) appears to be the best approach to reduce the risk of both cardiovascular diseases and cancers, in particular breast cancer.

  18. Peracetic acid as disinfectant of municipal wastewaters; L'acido peracetico nella disinfezione dei reflui urbani

    Energy Technology Data Exchange (ETDEWEB)

    Funari, E. [Istituto Superiore di Sanita' , Laboratorio di Igiene Ambientale, Reparto di Medicina Ambientale, Rome (Italy); Lopez, A. [Consiglio Nazionale delle Ricerche, Istituto di Ricerca sulle Acque, Reparto di Chimica e Tecnologia delle Acque, Bari (Italy)

    2000-09-01

    Based on the currently available literature, this paper is aimed at providing a sort of the <> on the use of peracetic acid (C{sub 3}COOOH{identical_to} Paa) as disinfectant of biologically treated municipal wastewater: the growing interest for this substance, used since many years in other sectors (e.g., food-industry, breweries, etc.) is mainly due to the claimed limited formation, if any, of harmful disinfecting by-products (Dbp) with consequent lack of toxicity in Paa treated wastewaters. Such features are just the opposite of those of chlorine, i.e. the most used disinfectant for municipal wastewater. During chlorine-disinfecting, in fact, numerous harmful organo-chlorinated Dbp are formed and, accordingly, the toxicity of chlorinated effluents results very high. In spite of the above reported <> properties of Paa, its use at large scale facilities is still restricted and this not only because of its costs but even for the limited knowledge concerning: the actual disinfecting effectiveness towards different pathogens, the nature and the toxicological properties of its potential Dbp, and the disinfecting performances at large scale facilities. The present paper, besides reporting an extensive and useful collection of references concerning Paa, provides a critical review on the current knowledge regarding specific Paa features such as: its disinfecting effectiveness towards different pathogenic micro-organisms, the nature and the toxicity of its disinfecting by-products, the environmental impact of Paa treated effluents, and the operative conditions used at large scale wastewater treatment plants. [Italian] Il presente lavoro, basandosi sui dati disponibili in letteratura, si propone di fare il punto sull'impiego dell'acido peracetico (CH{sub 3}COOOH{identical_to} PAA) come disinfettante di reflui urbani depurati. Il crescente interesse nei confronti di questa sostenza, gia' nota come disinfettante in

  19. ÁCIDOS GRASOS, ÉSTERES Y ESTEROLES DEL CUERPO FRUCTÍFERO DEL HONGO Laccaria laccata

    Directory of Open Access Journals (Sweden)

    Ivonne J. Nieto

    2008-04-01

    Full Text Available Del extracto en acetato de etilo del hongo comestible Laccaria laccata, se aislaron 3 ácidos grasos,  6 esteres etílicos, 5 esteroles y un triterpeno ergostánico. Los compuestos se identificaron por E.M. como ácido palmítico, ácido linoléico y ácido oléico, Hexadecanoato de etilo, 8-octadecenoato de etilo, 9-octadecenoato de etilo, 9,12-octadecadienoato de etilo, estearato de etilo,  eicosanoato de etilo, ergosta-2,5,7,9(11,22-pentaeno, ergosta-5,7,22-trien-3b-ol (ergosterol, ergosta-7,22-dien-3b-ol, ergosta-7-en-3b-ol, ergosta-5,7,9(11,22-tetraen-3b-ol y  estigmast-5-en-3b-ol. Tanto los ésteres como los dos últimos compuestos se reportan por primera vez en la especie laccata.

  20. Influencia del contenido graso y de otras variables sobre la capacidad de fusión del queso Cremoso Argentino

    Directory of Open Access Journals (Sweden)

    Zalazar, Carlos A.

    2004-09-01

    Full Text Available The influence of the fat content, pH, the ripening degree and the incorporation of whey proteins, by two different methods, on the meltability of Cremoso Argentino cheese was examined. Different experimental cheeses were made at pilot plant scale and their meltabilities were determined by a modified Schreiber test. Ripening degree and fat content showed a good correlation with the meltability. Though, cheeses with incorporation of whey proteins showed poor meltability, despite their yields increased. No correlation was found between pH and meltability inside the pH working range studied.En el presente trabajo se estudió la influencia del contenido de materia grasa, pH, grado de maduración e incorporación de proteínas de suero mediante dos vías diferentes sobre la capacidad de fusión del queso Cremoso Argentino. Utilizando una técnica modificada del test de Schreiber se analizó la capacidad de fusión de distintos quesos experimentales elaborados a escala piloto. El contenido graso y el grado de maduración afectaron positivamente la capacidad de fusión. La incorporación de proteínas de suero produjo mayores rendimientos pero la capacidad de fusión se vio fuertemente disminuida. No se observó una influencia clara del pH dentro de los límites estudiados

  1. Cardioprotective mechanism of omega-3 polyunsaturated fatty acids.

    Science.gov (United States)

    Endo, Jin; Arita, Makoto

    2016-01-01

    Omega-3 polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid and docosahexaenoic acid, are widely regarded as cardioprotective. Several large-scale, randomized clinical trials have shown that dietary intake of omega-3 PUFAs improves the prognosis of patients with symptomatic heart failure or recent myocardial infarction. Therefore, dietary consumption of omega-3 PUFA is recommended in international guidelines for the general population to prevent the occurrence of cardiovascular diseases (CVDs). However, the precise mechanisms underlying the cardioprotective effects of omega-3 PUFAs are not fully understood. Omega-3 PUFAs can be incorporated into the phospholipid bilayer of cell membranes and can affect membrane fluidity, lipid microdomain formation, and signaling across membranes. Omega-3 PUFAs also modulate the function of membrane ion channels, such as Na and L-type Ca channels, to prevent lethal arrhythmias. Moreover, omega-3 PUFAs also prevent the conversion of arachidonic acid into pro-inflammatory eicosanoids by serving as an alternative substrate for cyclooxygenase or lipoxygenase, resulting in the production of less potent products. In addition, a number of enzymatically oxygenated metabolites derived from omega-3 PUFAs were recently identified as anti-inflammatory mediators. These omega-3 metabolites may contribute to the beneficial effects against CVDs that are attributed to omega-3 PUFAs. Copyright © 2015 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

  2. Food supplementation for workers: flour enriched with omega -3

    Directory of Open Access Journals (Sweden)

    Adriana Nery de Oliveira

    2015-01-01

    Full Text Available The objective of this study was preparing a product (omega-3 flour to increase the nutritional value of the food for workers concerning the content of omega-3 fatty acids (n-3 FA. The omega-3 flour was prepared using waste (head sardines and leaves of carrot, flaxseed flour, manioc flour and spices. The fatty acids (FA concentration was analyzed by gas chromatography. A total of 28 FA were identified in the omega-3 flour. The concentration of eicosapentaenoic acid (EPA and docosahexaenoic acid (DHA were 329.23mg EPA 100 g-1 omega-3 flour and 545.35 mg DHA 100 g-1 omega-3 flour. To meet the minimum requirements of omega -3, it is necessary the intake 2.5 to 3 tablespoons (soup of omega-3 flour day-1.There were analyzed two meals (A and B generally consumed by workers without and with the addition of the omega-3 flour (1 and 2 tablespoons to verify if there was an increase of n-3 FA. It was concluded that there was a significant increase of these FA in both meals. It was found that the omega-3 flour is constituted of a good nutritional value, especially the n-3 FA, so the product can be used as a supplement in the feeding of the workers as well as in other segments.

  3. Semileptonic Decays of Heavy Omega Baryons in a Quark Model

    Energy Technology Data Exchange (ETDEWEB)

    Muslema Pervin; Winston Roberts; Simon Capstick

    2006-03-24

    The semileptonic decays of {Omega}{sub c} and {Omega}{sub b} are treated in the framework of a constituent quark model developed in a previous paper on the semileptonic decays of heavy {Lambda} baryons. Analytic results for the form factors for the decays to ground states and a number of excited states are evaluated. For {Omega}{sub b} to {Omega}{sub c} the form factors obtained are shown to satisfy the relations predicted at leading order in the heavy-quark effective theory at the non-recoil point. A modified fit of nonrelativistic and semirelativistic Hamiltonians generates configuration-mixed baryon wave functions from the known masses and the measured {Lambda}{sub c}{sup +} {yields} {Lambda}e{sup +}{nu} rate, with wave functions expanded in both harmonic oscillator and Sturmian bases. Decay rates of {Omega}{sub b} to pairs of ground and excited {Omega}{sub c} states related by heavy-quark symmetry calculated using these configuration-mixed wave functions are in the ratios expected from heavy-quark effective theory, to a good approximation. Our predictions for the semileptonic elastic branching fraction of {Omega}{sub Q} vary minimally within the models we use. We obtain an average value of (84 {+-} 2%) for the fraction of {Omega}{sub c} {yields} {Xi}{sup (*)} decays to ground states, and 91% for the fraction of {Omega}{sub c} {yields} {Omega}{sup (*)} decays to the ground state {Omega}. The elastic fraction of {Omega}{sub b} {yields} {Omega}{sub c} ranges from about 50% calculated with the two harmonic-oscillator models, to about 67% calculated with the two Sturmian models.

  4. Omega-3 and dyslexia: Uncertain connection.

    Science.gov (United States)

    Zelcer, Michal; Goldman, Ran D

    2015-09-01

    In light of the increase in the number of school-aged children diagnosed with dyslexia, what is the role of omega-3 supplements in the management of this condition? Dyslexia is the most common learning disability and is known to have multifactorial causes. Recent evidence suggests that there is a connection between defects in highly unsaturated fatty acid metabolism and neurodevelopmental disorders such as dyslexia. While the benefit of omega-3 supplementation for children with dyslexia has been studied, evidence remains limited. Unified diagnostic criteria for dyslexia, objective measures of fatty acid deficiency, and close monitoring of dietary intake are some of the factors that would improve the quality of research in the field. Copyright© the College of Family Physicians of Canada.

  5. The structure of omega3 food emulsions

    DEFF Research Database (Denmark)

    Jensen, Louise Helene Søgaard; Loussert, C.; Horn, Anna Frisenfeldt

    and add product value. Omega-3 PUFAs are rich in double bonds in their fatty acid chains and this attribute renders them highly susceptible to lipid oxidation. Omega-3 PUFAs can be added to food products as neat oil or as a delivery system such as oil-in-water emulsions. In this last configuration...... with the prooxidants in the water phase. Hence the structure, thickness and composition of the interface layer is expected to have a great impact on the oxidative stability of the emulsion. These layers are consisting of food grade emulsifiers such as milk phospholipids, casein and whey protein and are estimated......-in-water emulsions. Concerning chemical fixation, we adapted conventional protocols for preserving the emulsions, by developing agar pockets for encapsulation or embedding in capillary tubes (figure 1). Indeed to use chemical fixation with these samples is challenging because we need to minimize alterations...

  6. Superconducting RF separator for Omega Spectrometer

    CERN Multimedia

    1977-01-01

    The photo shows an Nb-deflector for the superconducting RF separator ready for installation in its cryostat (visible at the back). Each deflector was about 3 m long. L. Husson and P. Skacel (Karlsruhe) stand on the left, A. Scharding (CERN) stands on the right. This particle separator, the result of a collaboration between the Gesellshaft für Kernforschung, Karlsruhe, and CERN was installed in the S1 beam line to Omega spectrometer. (See Annual Report 1977.)

  7. Overview of Omega-3 Fatty Acid Therapies

    Science.gov (United States)

    Bradberry, J. Chris; Hilleman, Daniel E.

    2013-01-01

    The triglyceride (TG)-lowering benefits of the very-long-chain omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are well documented. Available as prescription formulations and dietary supplements, EPA and DHA are recommended by the American Heart Association for patients with coronary heart disease and hypertriglyceridemia. Dietary supplements are not subject to the same government regulatory standards for safety, efficacy, and purity as prescription drugs are; moreover, supplements may contain variable concentrations of EPA and DHA and possibly other contaminants. Reducing low-density lipoprotein-cholesterol (LDL-C) levels remains the primary treatment goal in the management of dyslipidemia. Dietary supplements and prescription formulations that contain both EPA and DHA may lower TG levels, but they may also increase LDL-C levels. Two prescription formulations of long-chain omega-3 fatty acids are available in the U.S. Although prescription omega-3 acid ethyl esters (OM-3-A EEs, Lovaza) contain high-purity EPA and DHA, prescription icosapent ethyl (IPE, Vascepa) is a high-purity EPA agent. In clinical trials of statin-treated and non–statin-treated patients with hypertriglyceridemia, both OM-3-A EE and IPE lowered TG levels and other atherogenic markers; however, IPE did not increase LDL-C levels. Results of recent outcomes trials of long-chain omega-3 fatty acids, fibrates, and niacin have been disappointing, failing to show additional reductions in adverse cardiovascular events when combined with statins. Therefore, the REDUCE–IT study is being conducted to evaluate the effect of the combination of IPE and statins on cardiovascular outcomes in high-risk patients. The results of this trial are eagerly anticipated. PMID:24391388

  8. OMEGA FY13 HED requests - LANL

    Energy Technology Data Exchange (ETDEWEB)

    Workman, Jonathan B [Los Alamos National Laboratory; Loomis, Eric N [Los Alamos National Laboratory

    2012-06-25

    This is a summary of scientific work to be performed on the OMEGA laser system located at the Laboratory for Laser Energetics in Rochester New York. The work is funded through Science and ICF Campagins and falls under the category of laser-driven High-Energy Density Physics experiments. This summary is presented to the Rochester scheduling committee on an annual basis for scheduling and planning purposes.

  9. Chaotic inflation and the omega problem

    Energy Technology Data Exchange (ETDEWEB)

    Mathews, G.J.; Graziani, F.; Kurki-Suonio, H.

    1990-12-01

    One of the most compelling features of inflationary cosmology is that it provides a solution to the flatness problem, i.e. an explanation of the fact that the ratio, {Omega}, of the present mass density to the closure density is so close to unity. Indeed, inflationary models naturally lead to a present value of the closure parameter which is equal to unity to many significant figures. At the same time, however, there are at least some observational indications that the present value of the closure parameter may be significantly less than unity. At the very least it is probably safe to say that there is no convincing evidence that the present mass density of the universe is not less than half of the closure density. This is the omega problem. The purpose of this paper will be to take the possibility that there is an omega problem seriously and look within the context of inflationary scenarios for a natural explanation as to why the present value of the closure parameter might be so small. 26 refs., 5 figs.

  10. Síntesis de alcoholes grasos insaturados a partir de metilésteres grasos usando catalizadores a base de rutenio y estaño soportados sobre alúmina

    Directory of Open Access Journals (Sweden)

    David Alexander Echeverri

    2011-01-01

    Full Text Available Los sistemas más promisorios para la síntesis de alcoholes grasos mediante hidrogenación catalítica son los basados en metales del grupo VIII con un promotor como el estaño, debido a que permiten realizar el proceso bajo condiciones moderadas, además que son menos tóxicos que los basados en cromo. A la fecha no se han realizado estudios de estos catalizadores con materias primas como mezclas de metil-ésteres o evaluaciones de la reutilización de ellos. En este artículo se estudia la hidrogenación de metilésteres derivados del aceite de palma y de metiloleato comercial con catalizadores de Ru-Sn/Al2O3 preparados por impregnación, a presión y temperatura moderadas (5 Mpa y 270 °C. Se encuentra que para una relación óptima Sn/Ru = 2 se obtiene mayor selectividad hacia el alcohol insaturado y menos hacia metilestearato.  La hidrogenación de metilésteres del aceite de palma con este catalizador da lugar a una mezcla de alcoholes insaturados y de saturados de 16 y 18 carbonos, además de ésteres pesados. El tipo de materia prima no tiene un efecto muy significativo sobre la actividad del catalizador; sin embargo, éste presenta desactivación a lo largo de varios ensayos debido a la pérdida de área catalítica.

  11. Measurement of the $\\Omega_{c}^{0}$ lifetime

    CERN Document Server

    Adamovich, M.I.; Alexandrov, Yu.A.; Barberis, D.; Beck, M.; Berat, C.; Beusch, W.; Boss, M.; Brons, S.; Bruckner, W.; Buenerd, M.; Buscher, C.; Charignon, F.; Chauvin, J.; Chudakov, E.A.; Dropmann, F.; Engelfried, J.; Faller, F.; Fournier, A.; Gerasimov, S.; Godbersen, M.; Grafstrom, P.; Haller, T.; Heidrich, M.; Hurst, R.B.; Konigsmann, Kay; Konorov, I.; Martens, K.; Martin, P.; Masciocchi, S.; Michaels, R.; Muller, U.; Newsom, C.; Paul, S.; Povh, B.; Ren, Z.; Rey-Campagnolle, M.; Rosner, G.; Rossi, L.; Rudolph, H.; Schmitt, L.; Siebert, H.W.; Simon, A.; Smith, V.J.; Thilmann, O.; Trombini, A.; Vesin, E.; Volkemer, B.; Vorwalter, K.; Walcher, T.; Walder, G.; Werding, R.; Wittmann, E.; Zavertyaev, M.V.

    1995-01-01

    We present the measurement of the lifetime of the Omega_c we have performed using three independent data samples from two different decay modes. Using a Sigma- beam of 340 GeV/c we have obtained clean signals for the Omega_c decaying into Xi- K- pi+ pi+ and Omega- pi+ pi- pi+, avoiding topological cuts normally used in charm analysis. The short but measurable lifetime of the Omega_c is demonstrated by a clear enhancement of the signals at short but finite decay lengths. Using a continuous maximum likelihood method we determined the lifetime to be tau(Omega_c) = 55 +13-11(stat) +18-23(syst) fs. This makes the Omega_c the shortest living weakly decaying particle observed so far. The short value of the lifetime confirms the predicted pattern of the charmed baryon lifetimes and demonstrates that the strong interaction plays a vital role in the lifetimes of charmed hadrons.

  12. Study of the centrally produced [omega][rho][sup 0] and [omega][omega] systems in pp interactions at 300 GeV/c

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, T.A.; French, B.R.; Kirk, A.; Knudson, K.; Redaelli, N.; Rossi, L. (CERN, European Organization for Nuclear Research, Geneva (Switzerland)); Benayoun, M.; Kahane, J.; Leruste, P.; Malamant, A.; Narjoux, J.L.; Sene, M.; Sene, R. (Coll. de France, 75 - Paris (France)); Bloodworth, I.J.; Carney, J.N.; Kinson, J.B.; Villalobos Baillie, O.; Votruba, M.F. (Birmingham Univ. (United Kingdom). Physics Dept.); Evangelista, C.; Ghidini, B.; Girone, M.; Jacholkowski, A.; Lenti, V.; Navach, F.; Palano, A.; Zito, G. (Bari Univ. (Italy). Dipt. di Fisica INFN, Bari (Italy)); Stassinaki, M.; Vasiliadis, G. (Athens Univ. (Greece). Nuclear Physics Dept.); WA76 Collaboration

    1993-05-01

    We have performed a search for vector-vector final states centrally produced in proton interactions at 300 GeV/c using the CERN [Omega] spectrometer. Evidence is found for [omega][rho][sup 0] production in the reaction pp[yields]p[sub f](2[pi][sup +]2[pi]-[pi][sup 0])p[sub s] and for [omega][omega] production in the reaction pp[yields]p[sub f](2[pi][sup +]2[pi][sup -]2[pi][sup 0])p[sub s]. However no evidence is found for [omega][phi] production in the reaction pp[yields]p[sub f].(K[sup +]K[sup -][pi][sup +][pi][sup -][pi][sup 0])p[sub s]. (orig.).

  13. Efecto del D-004, un extracto del fruto de Roystonea regia y omega-3 en el modelo de nado forzado en ratones Effect of D-004, a fruit extact from Roystonea regia and Omega-3 in a model of forced swimming in mice

    Directory of Open Access Journals (Sweden)

    Daisy Carbajal Quintana

    2010-03-01

    Full Text Available La depresión se encuentra entre las principales causas de morbilidad y mortalidad de la población adulta y su manejo farmacológico incluye, entre otras opciones alternativas, el uso de la medicina complementaria, como es el caso del aceite de pescado rico en ácidos grasos omega-3 (AGw3. El D-004, extracto lipídico de los frutos de la palma real (Roystonea regia que consiste en una mezcla de ácidos grasos, ha mostrado poseer una moderada acción antidepresiva. El objetivo de este trabajo consistió en comparar los efectos del tratamiento oral con D-004, con los AGw3 y con su terapia combinada en el modelo del nado forzado en ratones. Para ello, ratones machos se distribuyeron en 8 grupos: uno control tratado con el vehículo, dos con D-004 (250 y 500 mg/kg , dos con AGw3 (250 y 500 mg/kg, dos con la combinación y uno con imipramina (10 mg/kg i.p.. Todos los tratamientos disminuyeron significativamente el tiempo de inmovilidad con respecto al control, sin diferencias entre dosis similares de los respectivos tratamientos. En conclusión, el D-004, los AGw3 y su terapia combinada resultaron igualmente efectivos en reducir el tiempo de inmovilidad de los ratones, sin manifestarse efectos aditivos o sinérgicos con la administración conjunta de ambas sustancias.Depression is among the major causes of morbidity and mortality of adult population and its pharmacologic management includes among other alternative options, the use of the complementary medicine, e.g. the fish oil rich in Omega-3 fatty acids (AGw3. The D-004, a lipid extract of Real Palm fruits (Roystonea regia consisting of a fatty acid mixture, has a moderate antidepressant action. The aim of present paper was to compare the effects of oral treatment using D-004 with the AGw3 and with its combined therapy in forces swimming in mice. Thus, the male mice were distributed into 8 groups: one as control treated with vehicle, two with D-004 (250 and 500 mg.kg, two with AGw3 (250 and 500

  14. Simulationen zur Optimierung der omega-Rekonstruktion in ALICE

    CERN Document Server

    AUTHOR|(CDS)2239688; Khoukaz, Alfons

    In this thesis pp-collisions at $\\sqrt{s}$ = 7 TeV are simulated using PYTHIA and the produced omega-mesons are reconstructed via the $\\omega \\to \\pi^+\\pi^-\\pi^0$ decay-channel. By using further simulations of single omega-mesons, kinematic angle cuts are extracted and applied to the simulation data in order to check, whether or not the reconstruction can be improved.

  15. Omega-3 Fatty Acids and Cardiovascular Disease: Are There Benefits?

    OpenAIRE

    Bowen, Kate J.; Harris, William S.; Kris-Etherton, Penny M

    2016-01-01

    Opinion statement Early secondary prevention trials of fish and omega-3 polyunsaturated fatty acid (PUFA) capsules reported beneficial effects on cardiovascular disease (CVD) outcomes, including all-cause mortality and sudden cardiac death. These clinical findings, as well as observational and experimental data, demonstrated that omega-3 PUFAs reduced the risk of coronary outcomes and overall mortality and were the basis for recommendations made in the early 2000s to increase omega-3 PUFA int...

  16. Composición del contenido de ácidos grasos en tres poblaciones mexicanas de Artemia franciscana de aguas epicontinentales

    Directory of Open Access Journals (Sweden)

    Aída Malpica Sánchez

    2004-03-01

    Full Text Available En este trabajo se presenta la composición y el porcentaje de ácidos grasos de tres poblaciones mexicanas de Artemia franciscana de aguas epicontinentales; dos provienen de lugares silvestres (Coahuila y San Luis Potosí y una (Texcoco de un cultivo alimentado con Spirulina. Para la determinación de los ácidos grasos de cada población se extrajeron los lípidos totales por el método soxhlet y se esterificaron los ácidos grasos; posteriormente, mediante cromatografía de gases se determinó la composición y el porcentaje de los mismos. Los resultados muestran que la población de Texcoco contiene los seis ácidos grasos relevantes para peces y crustáceos en la acuicultura (16:0; 16:1; 18:1; 18:2w6; 18:3w3 y 20:5w3; mientras que la Artemia de San Luis Potosí resultó ser la más pobre en estos ácidos y la población de Coahuila, aunque mostró un perfil amplio, carece del ácido linolénico, ácido esencial y precursor de otros. Al comparar estos resultados, con datos ecológicos de estas tres poblaciones publicados previamente, se puede señalar que el ambiente es determinante para este crustáceo ya que Artemia de Texcoco provenía de un cultivo alimentado con Spirulina y fue la población que mostró mayor variedad de ácidos grasos. Las otras dos poblaciones son silvestres, con hábitats diferentes, la Artemia de Coahuila vive en aguas ricas en sulfatos y la de San Luis Potosí habita en vasos evaporadores de sal construidos con piedra de cantera y por lo tanto con escaso crecimiento de fitoplancton, ambas poblaciones mostraron deficiencias de ácidos grasos esenciales, sobre todo ésta últimaIn this paper is presented the percentage of fatty acids composition of three Artemia franciscana Mexican populations of epicontinentals waters; two are from natural environments (Coahuila and San Luis Potosí and one (Texcoco is a culture fed with Spirulina. Determination of fatty acids composition in each population, was performed by

  17. Suplementación enteral con ácidos grasos esenciales en recién nacidos pretérmino

    Directory of Open Access Journals (Sweden)

    Virginia Díaz-Argüelles Ramírez-Corría

    2001-03-01

    Full Text Available La tasa de crecimiento de recién nacidos (RN de muy bajo peso al nacer es muy elevada, sobre todo hasta que alcanzan el término y la ingesta balanceada de ácidos grasos esenciales es necesaria para un desarrollo adecuado de las membranas celulares fundamentalmente de cerebro y retina. Los tejidos de animales alargan y desaturan ácidos grasos progenitores, y esta conversión a ácidos grasos poliinsaturados de cadena larga se encuentra bajo regulación activa. En el RN pretérmino estos mecanismos son inmaduros y por tanto el ácido araquidónico y el docosahexaenoico se consideran esenciales, si se tiene en cuenta que el cerebro utiliza éstos como único perfil de ácidos grasos poliinsaturados de cadena larga. La fluidez de las membranas celulares dependerá del tipo de fosfolípido de las membranas y sobre todo de la longitud y saturación de la cadena acílica. La síntesis de prostaglandinas y tromboxanos en el RN pretérmino puede variar de acuerdo con la ingesta de ácido araquidónico. A pesar de que las necesidades de ácidos grasos esenciales están estimadas en unos pocos miligramos relacionados con la ingesta energética total, es preciso que exista una proporción adecuada entre el aporte de las 2 familias de ácidos grasos. La FAO/OMS y la ESPGAN han hecho recomendaciones para el aporte de ácido linoleico y a-linolénico en fórmulas infantiles para RN pretérmino, y mantienen una relación 5/15. En estos casos es necesaria también la suplementación con antioxidantes, para prevenir la peroxidación lipídica a la que están expuestos neonatos en oxígeno y con ventilación mecánica.The growth rate of very low birth weight newborn infants is considerably high, mainly until they reach the term, and a balanced intake of essential fatty acids is necessary for an adequate development of the cellular membranes fundamentally from the brain and retina. The tissues from animals lengthen and desaturate progenitor fatty acids and this

  18. Liposucción en Cirugía Reparadora (desengrasamiento de colgajos cutáneos y miocutáneos, exéresis de acúmulos grasos y autotransplante de grasa)

    OpenAIRE

    J.Mª Serra Renom; R. Vila Rovira; Recalde, M.

    2013-01-01

    La liposucción es una técnica quirúrgica de gran utilidad para la remodelación de acúmulos grasos y para el desgrasamiento de los colgajos cutáneos, miocutáneos o musculares. Para el desgrasamiento de los colgajos la realizamos después del año de efectuado el colgajo. También la empleamos en acúmulos grasos, en la reconstrucción mamaria postmastectomía, y acúmulos grasos periféricos en la reducción mamaria. Igualmente en el tratamiento de cicatrices deprimidas con prominencia de tejidos vecin...

  19. Liposucción en Cirugía Reparadora (desengrasamiento de colgajos cutáneos y miocutáneos, exéresis de acúmulos grasos y autotransplante de grasa

    Directory of Open Access Journals (Sweden)

    J.Mª Serra Renom

    2013-12-01

    Full Text Available La liposucción es una técnica quirúrgica de gran utilidad para la remodelación de acúmulos grasos y para el desgrasamiento de los colgajos cutáneos, miocutáneos o musculares. Para el desgrasamiento de los colgajos la realizamos después del año de efectuado el colgajo. También la empleamos en acúmulos grasos, en la reconstrucción mamaria postmastectomía, y acúmulos grasos periféricos en la reducción mamaria. Igualmente en el tratamiento de cicatrices deprimidas con prominencia de tejidos vecinos. En zonas deprimidas la realización del autotransplante de grasa nos ha dado buenos resultados.

  20. Análisis ultraestructural de membranas de glóbulos grasos lácteos de calostro y leche humana

    OpenAIRE

    Hernández, Francisco; Akahori, Hiroshi

    2016-01-01

    Se describen ultraestructuralmente los glóbulos grasos lácteos y sus membranas, a partir de leche y calostro de origen humano. Al microscopio electrónico de barrido los glóbulos aparecen como estructuras esferoides con algunas irregularidades en su superficie. Al micriscopio electrónico de transmisión se ve que esas irregularidades están compuestas por islotes de un material morfológicamente similar al citoplasma, en el que aparecen estructuras similares a fragmentos de retículo endoplasmátic...

  1. Producción de Ácidos Grasos Poliinsaturados a partir de Biomasa Microalgal en un Cultivo Heterotrófico

    Directory of Open Access Journals (Sweden)

    Gloria Inés Leal Medina

    2017-06-01

    Full Text Available El trabajo aquí presentado se enfocó en la producción de ácidos grasos poliinsaturados o PUFA’s (por sus siglas del inglés PolyUnsaturated Fatty Acids a partir de biomasa microalgal en un cultivo heterotrófico. Para esto, se utilizaron las algas Chlorella sp. y Scenedesmus sp., en condiciones heterotróficas, posteriormente se seleccionó la cepa con mayor productividad, se realizaron las cinéticas con ambas algas para cuantificar la concentración de biomasa, glucosa, nitrógeno y fósforo; se extrajeron los lípidos y se analizaron por cromatografía de gases. El cultivo heterotrófico se estableció en un reactor de tanque agitado de flujo continuo o CSTR (por sus siglas del inglés Continuous Stirred Tank Reactor de 1L, con las siguientes condiciones; 28°C, 1vvm, pH 6,8 y relación C/N 12:1. Luego, se realizó el cultivo en un “Biorreactor BioFlo 115” con volumen de 10L y se determinó la productividad de los lípidos obtenidos. El perfil lipídico permitió establecer que el ácido graso obtenido en mayor cantidad en CHL2 es el ácido oleico (C 18:1 con un porcentaje igual al 28,75 del total de ácidos grasos, también se destacan la acumulación de los ácidos grasos palmitoléico (C 16:1 con 19,75%, ácido araquídico (C 20:0 con 19,37%, ácido linoleico (C 18:2 con 11,86%, ácido palmítico (C 16:0 con 7,24%, ácido linolénico (ɤ-C 18:3 con 2,61%, ácido erúcico (C 22:1 con 4,61% y ácido esteárico (C 18:0 2,4%.

  2. Capacidad antioxidante y composición de ácidos grasos de diferentes partes de Adenocarpus complicatus (Fabaceae) de Turquía

    OpenAIRE

    Berber, Adnan; Zengin, Gokhan; Aydin Sanda, Murad; Uysal, Tuna

    2014-01-01

    Adenocarpus complicatus se distribuye por toda la península de Anatolia y es ampliamente utilizado para la nutrición humana y animal. El propósito de este trabajo fue estudiar las propiedades antioxidantes y la composición de ácidos grasos de diferentes partes de la planta (frutos y partes mezcladas). Las especies fueron recolectadas en Golyuzu, Seydisehir, cerca de la provincia Konya en Turquía. Para preparar los extractos metanólicos se tomó una muestra de 15g de frutas y partes mezcladas d...

  3. Efecto de los ácidos grasos hiperoxigenados en la microcirculación de pacientes con pie diabético

    OpenAIRE

    Sánchez Ríos, Juan Pedro

    2008-01-01

    La Diabetes Mellitus es una pandemia mundial. Actualmente se estima que la prevalencia de la Diabetes en el mundo es del 4.5%. Aproximadamente el 15% de los diabéticos desarrollarán una úlcera en el pie a lo largo de su vida. En la prevención y tratamiento de úlceras en Pie Diabético es importante también considerar, la integridad física y funcional de la piel del paciente para que pueda ejercer su acción protectora ante agresiones externas. Los ácidos grasos hiperoxigenados (AGHO) s...

  4. Estudio de la composición en ácidos grasos del aceite de las semillas en algunas plantas silvestres españolas

    Directory of Open Access Journals (Sweden)

    Vioque, J.

    1994-06-01

    Full Text Available The fatty acid composition of 34 species of plants from a variety of families that grow wild in the Iberian Peninsula was analysed. The aim to the survey was to indentify oils that contain a mix of fatty acids that from a qualitative or quantitative point of view have a commercial value. Because of the diverse taxonomic origin of the samples, the oil content between species was very variable, fluctuating between an average value of 3.4% in the Caryophyllaceae and 31.1% in Euphorbiaceae. Like the oil content, the fatty acid composition was quite variable, but, in general, the main fatty acids were palmitic, oleic, linoleic and linolenic acid, while in the Brassicaceae and in the Apiaceae erucic acid and petroselinic acid were the principal fatty acids respectively.

    Se ha estudiado la composición en ácidos grasos del aceite de las semillas en 34 plantas silvestres de la Península Ibérica. Se pretende la obtención de aceites con una composición en ácidos grasos que cualitativa o cuantitativamente puedan resultar de interés desde un punto de vista comercial. Debido al origen taxonómico tan diverso de las muestras, el contenido en aceite resulta muy variable, oscilando entre un valor medio del 3.4% en las Caryophyllaceae y el 31.1% de media en las Euphorbiaceae. Como el contenido en aceite, la composición en ácidos grasos es también bastante Variable, pero en general los principales ácidos grasos son palmítico, oleico, linoleico y linolénico, mientras que en las Brassicaceae domina el ácido erúcico y en las Apiaceae el ácido petroselínico.

  5. Inmunomodulación ejercida por los ácidos grasos de la dieta en animales de experimentación y humanos

    Directory of Open Access Journals (Sweden)

    Alvarez de Cienfuegos López, G.

    2000-06-01

    Full Text Available Several studies have reported that fatty acids act as modulatory agents of immune response of experimental animals and humans. In this paper, we do and overview of the performed studies by using of unsaturated fatty acids and their influence on several immunitary parameters in studies carried out in vitro as well as ex vivo. It has been shown that unsaturated fatty acids are involved in the reduction of lymphocyte proliferation, cytokine production and natural killer cell activity. On the other hand, in this article we have reviewed the mechanisms by which fatty acids modulate the immune response: I membrane fluidity alteration; II production of lipid peroxides; III eicosanoid production; IV gene expression modulation.Una gran cantidad de estudios han puesto de manifiesto la acción de los ácidos grasos como agentes moduladores de la respuesta inmune de animales y humanos. En este artículo hacemos una revisión de los estudios llevados a cabo tanto en experiencias realizadas en cultivos in vitro como en ensayos ex vivo, los cuales demuestran que los ácidos grasos, generalmente de naturaleza insaturada participan en la modulación de una gran cantidad de parámetros que forman parte de la respuesta inmune. Se ha demostrado que los ácidos grasos insaturados, están implicados en la reducción de la linfoproliferación, producción de citoquinas, actividad de las células natural killer, etc. Por otra parte, en este artículo tratamos de dilucidar cual es el mecanismo por el que los ácidos grasos ejercen esta acción: I alteración de la fluidez de la membrana plasmática; II Formación de peróxidos lipídicos; III Producción de eicosanoides; IV Modulación de la expresión de genes.

  6. Consumo de fructosa y sus implicaciones para la salud: malabsorción de fructosa e hígado graso no alcohólico

    OpenAIRE

    María Jesús Riveros; Alejandra Parada; Paulina Pettinelli

    2014-01-01

    La ingesta de fructosa se ha incrementado considerablemente en los últimos años, especialmente bajo la forma de jarabe de maíz alto en fructosa, debido a su gran poder edulcorante. Diversos estudios, han asociado su elevado consumo con alteraciones metabólicas, hígado graso no alcohólico y malabsorción de fructosa, entre otras patologías. Esta revisión tiene como objetivo actualizar acerca del efecto de la alta ingesta de fructosa en el hígado e intestino, asociada principalmente a alimentos ...

  7. Estudio del efecto de los ácidos grasos poliinsaturados, polifenoles e iminociclitoles sobre marcadores relacionados con el síndrome metabólico

    OpenAIRE

    Molinar Toribio, Eunice María

    2015-01-01

    La prevalencia del denominado Síndrome Metabólico (SM) está aumentando rápidamente en todo el mundo a tal punto que se está convirtiendo en un problema de salud global. Se conoce como SM a un conjunto de factores de riesgo para la salud, que incluyen la obesidad (obesidad central), resistencia a la insulina (RI), dislipidemia, hígado graso no alcohólico y la hipertensión. Estas alteraciones se han relacionado con un alto riesgo de desarrollar diabetes tipo 2 (DM2) y enfermedades cardiovascula...

  8. Embolismo graso en un niño con distrofia muscular de duchenne y fractura bilateral de fémur. una rara asociación.

    OpenAIRE

    Vergara Amador, Enrique; Galván Villamarín, Fernando; Piña Quintero, Marcela

    2011-01-01

    Las fracturas de fémur en pacientes que sufren de distrofiamuscular de Duchenne (DMD) son frecuentes, con unaincidencia entre 15-44 por ciento. El embolismo grasose presenta en fracturas de huesos largos generalmenteasociado a trauma de alta energía o a lesiones extensasde tejidos blandos. El diagnóstico de embolismo grasono es tan frecuente en niños posiblemente porque cursacon presentaciones subclínicas. No existen reportesde embolismo graso asociado a distrofia muscular deDuchenne. Informa...

  9. DESARROLLO DE METODOLOGIAS ANALITICAS PARA LA DETERMINACION DE HIODROCARBUROS AROMATICOS POLICICLICOS EN ALIMENTOS GRASOS MEDIANTE ESPECTROSCOPIA DE FLUORESCENCIA Y CALIBRACION MULTIVARIADA

    OpenAIRE

    ALARCON RODRIGUEZ, FRANCIS PAMELA

    2013-01-01

    Los hidrocarburos aromáticos policíclicos (PAHs), generados por combustión incompleta de materia orgánica, presentan particular interés debido a sus características cancerígenas y/o mutagénicas. Para el ser humano una de las vías de exposición a los PAHs es el consumo de alimentos grasos como los aceites vegetales. Los principales problemas de la determinación de PAHs en estas matrices oleosas son su baja concentración y la presencia de diversos interferentes. En general, su determin...

  10. Distrofia muscular de Duchenne y defecto de oxidación de ácidos grasos en un paciente pediátrico

    OpenAIRE

    Alejandra Acosta-Gualandri; Mildred Jiménez-Hernández

    2014-01-01

    Paciente pediátrico, con el diagnóstico de distrofia muscular de Duchenne y deficiencia de acil-CoA deshidrogenasa de cadenas medias, ambas patologías confirmadas por medio de análisis molecular, al detectarse la deleción de los exones 45 al 50 en el gen DMD, y la mutación A985G en estado homocigoto del gen ACADM. El paciente presenta una enfermedad metabólica debido a un trastorno en la oxidación mitocondrial de los ácidos grasos, con una clínica caracterizada por hipoglicemias no cetósicas,...

  11. Efecto de Tres Sistemas de Alimentación sobre el Comportamiento Productivo y Perfil de Ácidos Grasos de Carcasa de Cuyes (Cavia porcellus)

    OpenAIRE

    Huamaní Ñ., Genaro; Departamento Académico de Nutrición, Facultad de Zootecnia, Universidad Nacional Agraria La Molina, Lima; Zea M., Otto; Departamento Académico de Nutrición, Facultad de Zootecnia, Universidad Nacional Agraria La Molina, Lima; Gutiérrez R., Gustavo; Departamento Académico de Producción, Facultad de Zootecnia, Universidad Nacional Agraria La Molina, Lima; Vílchez P., Carlos; Departamento Académico de Nutrición, Facultad de Zootecnia, Universidad Nacional Agraria La Molina, Lima

    2016-01-01

    El objetivo del presente estudio fue evaluar el efecto de tres sistemas de alimentación sobre la respuesta productiva y el perfil de ácidos grasos en la carcasa de cuyes. Se emplearon 18 cuyes machos de 21 días de edad distribuidos aleatoriamente en tres grupos y alojados en jaulas galvanizadas. Los tratamientos fueron: T1, alfalfa verde; T2, alimentación mixta [alimento balanceado + alfalfa verde (10% del PV)]; y T3, alimentación integral (solo alimento balanceado). Se determinó la ganancia ...

  12. Biodiésel de ésteres etílicos de ácidos grasos : correlación composición-propiedades

    OpenAIRE

    Alonso Castro, Elena

    2014-01-01

    Debido a la situación energética actual, el aumento de la demanda de petróleo y precio, así como su carácter no renovable, hace necesaria la búsqueda de alternativas viables para su uso como combustible. Una de ellas es el biodiésel, ya que tiene características similares y puede ser usado como sustituto de los combustibles convencionales, sin necesidad de grandes modificaciones en el motor. Hasta ahora los estudios se habían centrado en los esteres metílicos de ácidos grasos (FAMEs) por razo...

  13. Cambios en el perfil de ácidos grasos de filete de tilapia nilótica Oreochromis niloticus en respuesta a diferentes fuentes lipídicas

    OpenAIRE

    Moreno Poveda, Jenny Marcela

    2013-01-01

    Con el objetivo de modificar el perfil de ácidos grasos (AG) en el filete de tilapia nilótica (Oreochromis niloticus), se fabricaron cuatro dietas con: aceite de pescado (AP), aceite de palma (APL), semilla de chía (SC) o semilla de lino (SL). El experimento fue realizado durante 45 días en la represa de Betania (Huila), en 20 jaulas flotantes, cada una con 504 peces de 557±16,87g, distribuidos bajo un diseño completamente al azar. Al finalizar el periodo experimental fueron muestreados 21 pe...

  14. Adipose Tissue Omega-3 and Omega-6 Fatty Acid Content and Breast Cancer in the EURAMIC Study

    OpenAIRE

    Simonsen, Neal; Pieter van 't Veer; Strain, John J.; Martin-Moreno, José M.; Huttunen, Jussi K; Navajas, Joaquin Femández-Crehuet; Martin, Blaise C.; Thamm, Michael; Kardinaal, Alwine F. M.; Kok, Frans J; Kohlmeier, Lenore

    2017-01-01

    The fatty acid content of adipose tissue in postmenopausal breast cancer cases and controls from five European countries in the European Community Multicenter Study on Antioxidants, Myocardial Infarction, and Cancer (EURAMIC) breast cancer study (1991 -1992) was used to explore the hypothesis that fatty acids of the omega-3 family inhibit breast cancer and that the degree of inhibition depends on background levels of omega-6 polyunsaturates. Considered in isolation, the level of omega-3 or om...

  15. Effect of a diet enriched with omega-6 and omega-3 fatty acids on the pig liver transcriptome.

    Science.gov (United States)

    Szostak, Agnieszka; Ogłuszka, Magdalena; Te Pas, Marinus F W; Poławska, Ewa; Urbański, Paweł; Juszczuk-Kubiak, Edyta; Blicharski, Tadeusz; Pareek, Chandra Shekhar; Dunkelberger, Jenelle R; Horbańczuk, Jarosław O; Pierzchała, Mariusz

    2016-01-01

    The optimal ratio of omega-6 to omega-3 polyunsaturated fatty acids (PUFAs) is important for keeping the homeostasis of biological processes and metabolism, yet the underlying biological mechanism is poorly understood. The objective of this study was to identify changes in the pig liver transcriptome induced by a diet enriched with omega-6 and omega-3 fatty acids and to characterize the biological mechanisms related to PUFA metabolism. Polish Landrace pigs (n = 12) were fed diet enriched with linoleic acid (LA, omega-6) and α-linolenic acid (ALA, omega-3) or standard diet as a control. The fatty acid profiling was assayed in order to verify how feeding influenced the fatty acid content in the liver, and subsequently next-generation sequencing (NGS) was used to identify differentially expressed genes (DEG) between transcriptomes between dietary groups. The biological mechanisms and pathway interaction networks were identified using DAVID and Cytoscape tools. Fatty acid profile analysis indicated a higher contribution of PUFAs in the liver for LA- and ALA-enriched diet group, particularly for the omega-3 fatty acid family, but not omega-6. Next-generation sequencing identified 3565 DEG, 1484 of which were induced and 2081 were suppressed by PUFA supplementation. A low ratio of omega-6/omega-3 fatty acids resulted in the modulation of fatty acid metabolism pathways and over-representation of genes involved in energy metabolism, signal transduction, and immune response pathways. In conclusion, a diet enriched with omega-6 and omega-3 fatty acids altered the transcriptomic profile of the pig liver and would influence animal health status.

  16. Omega-3 Fatty Acids and Cardiovascular Disease: Are There Benefits?

    Science.gov (United States)

    Bowen, Kate J; Harris, William S; Kris-Etherton, Penny M

    2016-11-01

    Early secondary prevention trials of fish and omega-3 polyunsaturated fatty acid (PUFA) capsules reported beneficial effects on cardiovascular disease (CVD) outcomes, including all-cause mortality and sudden cardiac death. These clinical findings, as well as observational and experimental data, demonstrated that omega-3 PUFAs reduced the risk of coronary outcomes and overall mortality and were the basis for recommendations made in the early 2000s to increase omega-3 PUFA intake. In the last 6 years, however, results from both primary and secondary prevention trials have generally failed to show a beneficial effect of omega-3 PUFA supplementation, bringing current recommendations into question. Several possible reasons for these null findings have been proposed, including short treatment periods, relatively low doses of omega-3 PUFAs, small sample sizes, higher background omega-3 intakes, and the concurrent use of modern pharmacotherapy for CVD prevention. At least one of these caveats is being assessed in major clinical trials, with two omega-3 PUFA pharmacological agents being tested at doses of 4 g/day (instead of the more common omega-3 PUFAs "are ineffective" in general, only that they were not effective in the context in which they were tested. Accordingly, higher intakes of omega-3 PUFAs, either from fatty fish or from supplements, if continued for decades (as the epidemiological data support) are likely to contribute towards lower risk for CVD. At this time, evidence supports the consumption of a healthy dietary pattern with at least two servings per week of fatty fish. Omega-3 PUFA supplementation is a reasonable alternative for those who do not consume fish, although fish is the preferred source of omega-3 PUFAs because it also provides additional nutrients, some of which are often under-consumed.

  17. l aceite de atún como fuente de ácidos grasos ω-3 en el huevo de gallina

    OpenAIRE

    Vázquez-Valladolid, J. L.; Castillo-Badillo, C.; González-Alcorta, M.; Morales-Barrera, E.; Castillo-Domínguez, R. M.; S Carrillo-Domínguez

    2005-01-01

    Fish oils are a source of polyunsaturated omega 3 fatty acids (AG ω3), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which supply many benefits to human health. Tuna oil was used as a source of marine 3ω FA to enrich eggs by supplementing the diet of egg-laying hens with tuna oil. One hundred and twenty White Leghorn hens of 90 weeks old were allocated on three treatments with four replicates each, on a completely random design. Treatments consisted of adding 1 % and 2 %...

  18. COMPOSICION QUIMICA Y CONCENTRACION DE PRECURSORES DE ACIDO RUMENICO Y VACCENICO EN FORRAJES ALTERNATIVOS PARA LA ALIMENTACION DE RUMIANTES EN ECOSISTEMAS ARIDOS

    Directory of Open Access Journals (Sweden)

    Ricardo Ortega Pérez

    2009-07-01

    Full Text Available Se determinó el valor nutrimental de alfalfa henificada (AH, dos genotipos de fríjol yorimón [IT90K-277-2 (FYG18 y Sesenteño (FYG25], un clon de pasto taiwán (PT, un cultivar local de nopal en dos presentaciones, pencas tiernas de 15 días de edad o ";;;nopalitos";;; (NT y pencas maduras (NM de 60 días de edad y germinado de semillas de maíz (GM del genotipo ASGROW 7573. Se cuantificó el contenido de materia seca (MS, proteína cruda (PC, lípidos totales (LT, cenizas (C, fibra cruda (FC y energía bruta (EB, así como la concentración de ácido linoleico (LA, ácido α-linolénico (ALA, ácidos grasos poliinsaturados (PUFA y ácidos grasos n-3. Los resultados revelan que los genotipos de frijol yorimón FYG25 y FYG18, mostraron el mayor contenido de PC. Respecto a la concentración de LT, el genotipo de yorimón FYG25 mostró la mayor cantidad seguido del FYG18 y AH. Los forrajes verdes de frijol yorimón (FYG25 y FYG18, así como el pasto Taiwán tuvieron el contenido mayor de ácido α-linolénico. Las semillas de germinado de maíz mostraron los contenidos mayores de ácido linolénico seguido del nopal tierno. Ambos ácidos grasos poliinsaturados (ALA y LA son precursores del ácido ruménico y del ácido vaccénico en rumiantes. Por lo tanto, el uso de estos forrajes verdes en la alimentación de rumiantes es una alternativa que podría modificar las proporciones de ácido grasos en la leche y la carne con el propósito de incrementar los PUFA, específicamente el ácido ruménico así como el ácido vaccénico.

  19. Direct CP Violation in Charmed Hadron Decays via $\\rho-\\omega$ Mixing

    OpenAIRE

    Guo, X. -H.; Thomas, A. W.

    1999-01-01

    We study the possibility of obtaining large direct CP violation in the charmed hadron decays $D^+ \\to \\rho^+ \\rho^0 (\\omega) \\to \\rho^+ \\pi^+\\pi^-$, $D^+ \\to \\pi^+ \\rho^0 (\\omega) \\to \\pi^+ \\pi^+\\pi^-$, $D^0 \\to \\phi \\rho^0 (\\omega) \\to\\phi \\pi^+\\pi^-$, $D^0 \\to\\eta \\rho^0 (\\omega) \\to\\eta \\pi^+\\pi^-$, $D^0 \\to \\eta' \\rho^0 (\\omega) \\to\\eta' \\pi^+\\pi^-$, $D^0 \\to \\pi^0 \\rho^0 (\\omega) \\to \\pi^0 \\pi^+\\pi^-$, and $\\Lambda_c \\ra p \\rho^0 (\\omega) \\to p \\pi^+\\pi^-$ via $\\rho-\\omega$ mixing. The a...

  20. Needs in omega 3 and ocular pathologies

    Directory of Open Access Journals (Sweden)

    Bretillon Lionel

    2011-09-01

    Full Text Available Life expectancy at birth has regularly increased decade after decade, especially since the beginning of the 20th century: 15 years have been gained over the past 50 years. Changes in living and dietary habits during this time period have been associated with the development of various pathologies which represent a growing socioeconomic burden. Among age-related disorders, ocular diseases are the second most prevalent ones after 65 years. Age-related Macular Degeneration (AMD is the leading cause of visual impairment after the age of 50 years. Age is the prominent risk factor for AMD and is accompanied with both endogenous (including genetics and environmental factors, such as smoking habits and dietary factors (diet rich in cholesterol and saturated fatty acids. AMD is characterized by the loss of cells at the most central area of the retina, called macula. The neural retina is a highly structured neurosensory tissue that is responsible for the transduction pathway. The transduction pathway is initiated in photoreceptors where the light stimulus is coded into an electrical signal. This signal is transmitted to neighboured neurons and transferred to the brain via the optic nerve. The retinal pigment epithelium (RPE is the cellular and metabolic interface between the neural retina and choriocapillaris through Bruch’s membrane. The close association between RPE and photoreceptors is one of the factors that promote the efficacy of RPE to, in the one hand, provide nutrients and oxygen to photoreceptors and, in the other hand, eliminate the metabolic debris originating from shedding of the outer segments. Epidemiological data suggest that dietary habits privileging the consumption of omega- 3 long chain polyunsaturated fatty acids participate to prevent from the development of AMD (Sangiovanni et al., 2009. The mechanisms underlying the effects of omega-3 fatty acids remain unclear until now. The purpose of the present paper is to give a review on

  1. The Omega spectrometer in the West Hall.

    CERN Multimedia

    CERN PhotoLab

    1976-01-01

    Inside the hut which sits on top of the superconducting magnet are the TV cameras that observe the particle events occurring in the spark chambers in the magnet gap below. On the background the two beam lines feeding the spectrometer target, for separated hadrons up to 40 GeV, on the right, for 80 GeV electrons, on the left, respectively. The latter strikes a radiator thus sending into Omega tagged photons up to 80 GeV. On the foreground, the two sections of the large gas Cerenkov counter working at atmospheric pressure, used for trigger purpose.

  2. Progress of Rugby Hohlraum Experiments on Omega

    Science.gov (United States)

    Philippe, Franck; Tassin, Veronique; Casner, Alexis; Gauthier, Pascal; Seytor, Patricia; Monteil, Marie-Christine; Park, Hye-Sook; Robey, Harry; Ross, Steven; Amendt, Peter; Girard, Frederic; Villette, Bruno; Reverdin, Charles; Loiseau, Pascal; Caillaud, Tony; Landoas, Olivier; Li, Chi Kang; Petrasso, Richard; Seguin, Fredrick; Rosenberg, Markus

    2011-10-01

    The rugby hohlraum concept is predicted to enable better coupling and higher gains in the indirect drive approach to ignition. A collaborative experimental program is currently pursued on OMEGA to test this concept in preparation for future megajoule-scale ignition designs. A direct comparison of gas-filled rugby hohlraums with classical cylinders was recently performed, showing a significant (up to ~40%) observed x-ray drive enhancement and neutron yields that are consistently higher in the rugby case. This work extends and confirms our previous findings in empty rugby hohlraums.

  3. Gamma bang time analysis at OMEGA

    Energy Technology Data Exchange (ETDEWEB)

    McEvoy, A. M.; Herrmann, H. W.; Young, C. S.; Mack, J. M.; Kim, Y.; Evans, S.; Sedillo, T. [Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Horsfield, C. J.; Rubery, M. [Atomic Weapons Establishment, Aldermaston, Reading, RG7 4PR (United Kingdom); Miller, E. K. [National Security Technologies-Special Technologies Laboratory, Santa Barbara, California 93101 (United States); Stoeffl, W. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Ali, Z. A. [National Security Technologies, Livermore, California 94550 (United States)

    2010-10-15

    Absolute bang time measurements with the gas Cherenkov detector (GCD) and gamma reaction history (GRH) diagnostic have been performed to high precision at the OMEGA laser facility at the University of Rochester with bang time values for the two diagnostics agreeing to within 5 ps on average. X-ray timing measurements of laser-target coupling were used to calibrate a facility-generated laser timing fiducial with rms spreads in the measured coupling times of 9 ps for both GCD and GRH. Increased fusion yields at the National Ignition Facility (NIF) will allow for improved measurement precision with the GRH easily exceeding NIF system design requirements.

  4. Still unexploited atmospheric OMEGA/MEx observations

    Science.gov (United States)

    Gondet, B.; Bibring, J.-P.; Vincendon, M.

    2017-09-01

    Since the beginning of the mission (January 2004) OMEGA, the VIS-NIR hyperspectral imager onboard Mars Express has acquired regular limbs observations in conjunction with others instruments (HRSC, PFS, SPICAM and VMC). Scattering by clouds and dust was detected at different Ls, altitude, locations and local time, as well as specific emission (O2, H2O, CO2, CO). Composition and grain sizes can be derived from these measurements. Atmospheric detections are also made in nadir mode. This constitutes an important database largely unexploited at this point. We will present examples of detections concerning clouds, dust and emissions, and identify themes of potential collaborations.

  5. New insights into the health effects of dietary saturated and omega-6 and omega-3 polyunsaturated fatty acids

    Directory of Open Access Journals (Sweden)

    de Lorgeril Michel

    2012-05-01

    Full Text Available Abstract Cardiovascular diseases and cancers are leading causes of morbidity and mortality. Reducing dietary saturated fat and replacing it with polyunsaturated fat is still the main dietary strategy to prevent cardiovascular diseases, although major flaws have been reported in the analyses supporting this approach. Recent studies introducing the concept of myocardial preconditioning have opened new avenues to understand the complex interplay between the various lipids and the risk of cardiovascular diseases. The optimal dietary fat profile includes a low intake of both saturated and omega-6 fatty acids and a moderate intake of omega-3 fatty acids. This profile is quite similar to the Mediterranean diet. On the other hand, recent studies have found a positive association between omega-6 and breast cancer risk. In contrast, omega-3 fatty acids do have anticancer properties. It has been shown that certain (Mediterranean polyphenols significantly increase the endogenous synthesis of omega-3 whereas high intake of omega-6 decreases it. Finally, epidemiological studies suggest that a high omega-3 to omega-6 ratio may be the optimal strategy to decrease breast cancer risk. Thus, the present high intake of omega-6 in many countries is definitely not the optimal strategy to prevent cardiovascular disease and cancers. A moderate intake of plant and marine omega-3 in the context of the traditional Mediterranean diet (low in saturated and omega-6 fatty acids but high in plant monounsaturated fat appears to be the best approach to reduce the risk of both cardiovascular diseases and cancers, in particular breast cancer.

  6. Serum Omega-6/Omega-3 Ratio and Risk Markers for Cardiovascular Disease in an Industrial Population of Delhi

    Science.gov (United States)

    Gupta, Ruby; Lakshmy, Ramakrishnan; Abraham, Ransi Ann; Reddy, Kolli Srinath; Jeemon, Panniyammakal; Prabhakaran, Dorairaj

    2017-01-01

    High omega-6/omega-3 ratio intake promotes development of many chronic diseases. Secondary prevention studies though have demonstrated a decline in progression of many such diseases after reducing the intake, specific biochemical indices of cardiovascular disease risk markers have not been evaluated. We have evaluated the circulating levels of omega-6/omega-3 ratio and its effect on cardiovascular risk markers in India. Present study was conducted in industrial setting where employees were randomly selected. Data on their demographic characteristics were collected using pre-tested questionnaire. Fasting blood samples were collected from all the participants. Serum was separated and stored at −80°C till the time of analysis. Lipids were estimated using standard kits. Fatty acids in serum were estimated by Gas chromatography. The identified Omega-3 fatty acid included were 18:3 (Alpha-linolenic acid), 20:5 (Eicosapentenoic acid) & 22:6 (Docosahexenoic acid). Among omega-6 included were 18:2 (linoleic acid), 18:3 (gamma-linolenic acid) & 20:4 (Arachidonic acid). Complete data was available for 176 participants (89% males and 11% females) with mean age of 47.23 ± 6.00 years. The bmi of the participants was 24.88 ± 3.43 Kg/m2 and waist circumference was 91.50 ± 9.56 cm. The median of omega-6/omega-3 ratio in the study population was 36.69 (range: 6.21 - 183.69). The levels of total cholesterol, triglycerides, ldl-cholesterol and cholesterol/hdl ratio and apo B correlated significantly with omega-6/3 ratio. There was no correlation observed with hsCRP and LDL-particle size. A direct relationship of omega-6/omega-3 ratio with dyslipidemia was observed in our study. PMID:28919984

  7. Enzymatic Modification of Antioxidants Towards Omega-3 Oil Protection

    DEFF Research Database (Denmark)

    Yang, Zhiyong

    This PhD dissertation entitled “Enzymatic Modification of Antioxidants Towards Omega-3 Oil Protection” is primarily focused on synthesize of novel antioxidant from natural sources for better protection of oxidation-prone omega 3 oil. Selected phenolic acids were conjugated with fatty alcohols...

  8. The Secondary Standards Programme for OmegaCAM

    NARCIS (Netherlands)

    Verdoes Kleijn, G.; Vermeij, R.; Valentijn, E.; Kuijken, K.; Sterken, C.

    2007-01-01

    The OmegaCAM wide-field imager will start operations at the ESO VLT Survey Telescope at Paranal in 2007. The photometric calibration of OmegaCAM data depends on standard-star measurements that cover the complete 1°×1° FOV. A catalog fullfilling this requirement for 8 Landolt equatorial fields,

  9. Lipid profile and levels of omega-3 polyunsaturated fatty acids ...

    African Journals Online (AJOL)

    The intake of polyunsaturated fatty acids especially omega-3 is projected to be way below the recommended intake in Kenya. Thus, there is need to find other sources of polyunsaturated fatty acids (PUFAs). This study screened for the lipid profile and levels of omega-3 PUFAs in jackfruit and explored the variation in lipid ...

  10. The width of the {omega} meson in the nuclear medium

    Energy Technology Data Exchange (ETDEWEB)

    Ramos, A. [Universitat de Barcelona, Departament d' Estructura i Constituents de la Materia and Institut de Ciencies del Cosmos, Barcelona (Spain); Tolos, L. [Facultat de Ciencies, Instituto de Ciencias del Espacio (IEEC/CSIC) Campus Universitat Autonoma de Barcelona, Barcelona (Spain); Johann Wolfgang Goethe University, Frankfurt Institute for Advanced Studies (FIAS), Frankfurt am Main (Germany); Molina, R. [Research Center for Nuclear Physics (RCNP), Ibaraki (Japan); Oset, E. [Centro Mixto Universidad de Valencia-CSIC, Institutos de Investigacion de Paterna, Departamento de Fisica Teorica and IFIC, Aptdo. 22085, Valencia (Spain)

    2013-11-15

    We evaluate the width of the {omega} meson in nuclear matter. We consider the free decay mode of the {omega} into three pions, which is dominated by {rho}{pi} decay, and replace the {rho} and {pi} propagators by their medium-modified ones. We also take into account the quasielastic and inelastic processes induced by a vector-baryon interaction dominated by vector meson exchange, as well as the contributions coming from the {omega}{yields}K anti K mechanism with medium-modified K, anti K propagators. We obtain a substantial increase of the {omega} width in the medium, reaching a value of 121 {+-} 10 MeV at normal nuclear matter density for an {omega} at rest, which comes mainly from {omega}N {yields} {pi}{pi}N, {omega}NN {yields} {pi}NN processes associated to the dominant {omega} {yields} {rho}{pi} decay mode. The value of the width increases moderately with momentum, reaching values of around 200MeV at 600MeV/c. (orig.)

  11. Extracting the Omega- electric quadrupole moment from lattice QCD data

    Energy Technology Data Exchange (ETDEWEB)

    G. Ramalho, M.T. Pena

    2011-03-01

    The Omega- has an extremely long lifetime, and is the most stable of the baryons with spin 3/2. Therefore the Omega- magnetic moment is very accurately known. Nevertheless, its electric quadrupole moment was never measured, although estimates exist in different formalisms. In principle, lattice QCD simulations provide at present the most appropriate way to estimate the Omega- form factors, as function of the square of the transferred four-momentum, Q2, since it describes baryon systems at the physical mass for the strange quark. However, lattice QCD form factors, and in particular GE2, are determined at finite Q2 only, and the extraction of the electric quadrupole moment, Q_Omega= GE2(0) e/(2 M_Omega), involves an extrapolation of the numerical lattice results. In this work we reproduce the lattice QCD data with a covariant spectator quark model for Omega- which includes a mixture of S and two D states for the relative quark-diquark motion. Once the model is calibrated, it is used to determine Q_Omega. Our prediction is Q_Omega= (0.96 +/- 0.02)*10^(-2) efm2 [GE2(0)=0.680 +/- 0.012].

  12. Composición en ácidos grasos de la fracción lipídica del tocosh de maíz

    Directory of Open Access Journals (Sweden)

    Durand, Z. Honorio

    1994-12-01

    Full Text Available Corn's tocosh is a food consumed by children and adults in the andine region of Callejón de Huaylas in Peru, Germination and fermentation phenomena produced during its elaboration contribute to modify the chemical composition of the original corn; that is the case of the fatty acids in the lipidic fraction.
    The analytical data of the corn's tocosh, show the presence of trans isomers in non significant amount, an increase in linoleic acid related to the time of fermentation, and the presence of gamma linolenic acid.

    El tocosh de maíz es un alimento consumido por adultos y niños de la región andina del Callejón de Huaylas del Perú.
    Los fenómenos de germinación y fermentación que se producen durante su elaboración aseguran cambios en la composición química del maíz original; tal es el caso de los ácidos grasos de la fracción lipídica.
    Los resultados del análisis del tocosh de maíz, muestran la presencia de isómeros trans en cantidades no significativas, un incremento del ácido graso esencial linoleico en función del tiempo de fermentación y la presencia del ácido gamma linolénico.

  13. Síndrome de embolismo graso con predominio de síntomas neurológicos. [Fat embolism syndrome with predominance of neurological symptoms].

    Directory of Open Access Journals (Sweden)

    Diego Alejandro Rangel Rivera

    2016-11-01

    Full Text Available El síndrome de embolismo graso se refiere a un conjunto de signos y síntomas que se presentan de manera secundaria a la liberación de lípidos dentro de la circulación sanguínea. Este se presenta en alrededor del 1% de los pacientes con fracturas de fémur. La tríada clásica de este síndrome incluye dificultad respiratoria con hipoxemia, alteración neurológica y rash petequial. A pesar de las descripciones aisladas donde se documenta mejoría de los síntomas posterior a la administración de corticoesteroides, no existe clara evidencia de la utilidad de estos medicamentos por lo que el manejo actual es de soporte cardiovascular y respiratorio. Se presenta el caso de un paciente adulto jóven con síndrome de embolismo graso con manifestaciones respiratorias mínimas posterior a fractura traumática de fémur.

  14. Efectividad de los ácidos grasos hiperoxigenados en la prevención de las úlceras vasculares: Una revisión sistemática

    Directory of Open Access Journals (Sweden)

    Eva Vives Sánchez

    Full Text Available Objetivos: conocer la eficacia de los ácidos grasos hiperoxigenados (AGHO en la prevención de las úlceras vasculares. Determinar el nivel de evidencia existente sobre el uso de ácidos grasos hiperoxigenados en la prevención de las úlceras vasculares. Material y método: se realizó una búsqueda bibliográfica en la The Cochrane Library, The Joanna Briggs Institute, PubMed-Medline y CUIDEN. Para su evaluación se han seguido las recomendaciones del sistema GRADE para la valoraciún de la evidencia y la fuerza de las recomendaciones. Resultados: en The Cochrane Library y en The Joanna Briggs Institute no aparece ningún documento que haga referencia a los AGHO. En el resto de bases de datos encontramos estudios observacionales que hacen referencia a las úlceras vasculares y AGHO. Conclusiones: aun no disponiendo de ensayos clínicos que evidencien su uso, se han venido utilizando durante los últimos años, con resultados satisfactorios, en el cuidado de la piel de las personas con alteraciones vasculares en los miembros inferiores. De acuerdo con la clasificación GRADE, todos los estudios arrojan una calidad de evidencia baja, por lo cual estimamos necesario la puesta en marcha de investigaciones que aporten mayor evidencia científica.

  15. Marine lipids and the bioavailability of omega-3 fatty acids

    DEFF Research Database (Denmark)

    Mu, Huiling; Müllertz, Anette

    2015-01-01

    Marine lipids are enriched with omega-3 fatty acids, especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Omega-3 fatty acids are important membrane lipids and have many recognized health benefits, the bioavailability of these fatty acids can therefore be important for achieving...... the beneficial healthy effects. As important membrane lipids, the incorporation and depletion kinetics of EPA and DHA in biological membranes have been found to be different, DHA was depleted slowly from both erythrocyte and plasma membranes due to the slow re-synthesis of DHA in the body. The bioavailability...... of omega-3 fatty acids has been reported to be affected by several factors; among the important factors were the digestion and absorption processes of omega-3 containing lipids in the gastrointestinal tract. Both lipid structures and food structures can affect the bioavailability of omega-3 fatty acids...

  16. Recent advances in the field of omega-3-lipids

    DEFF Research Database (Denmark)

    Jacobsen, Charlotte

    consumption. Due to their polyunsaturated nature omega-3 lipids are highly susceptible to lipid oxidation. The last part of the presentation will discuss possible means to prevent or reduce lipid oxidation in omega-3 lipids in dietary supplements and in foods enriched with these healthy lipids. Possible means...... to prevent oxidation include antioxidant addition, optimisation of food processing conditions and the use of delivery systems for omega-3 lipids (e.g. emulsions and microencapsulated omega-3 powders).......During the last 15-20 years the use of fish and algae oils for human applications has received increasing attention from academia, industry and consumers. This is due to the fact that a growing body of evidence supports that marine omega-3 lipids have a wide range of health beneficial effects...

  17. Obtención de concentrados de ácidos grasos poliinsaturados por el método de los compuestos de inclusión de urea

    Directory of Open Access Journals (Sweden)

    Robles Medina, A.

    1995-06-01

    Full Text Available A concentration process for polyunsaturated fatty acids (PUFAs n-3 stearidonic (18:4 n-3, eicosapentaenoic (20:5 n-3 and docosahexaenoic (22:6 n-3 from cod liver oil using urea method has been thoroughly studied. The influence of urea/fatty acid ratio and crystallization temperature have been studied on both fatty acids recovery yield and fatty acid concentration. Methanol and ethanol have been used as urea solvent. The use of methanol and an urea/fatty acid ratio of 4:1, and 4°C were found to be the best conditions for SA (concentration 8,5%, yield 71,6 and DHA (59,8% and 100%, respectively. However, 28ºC was found to be the best temperature for EPA (28,7% and 75,6%, respectively. At temperatures below -12ºC, PUFAs also developed adducts compounds, mainly adducts derived from EPA. A variance analysis showed the urea/fatty acid ratio as the main factor affecting fatty acid concentration. At the same time, high urea/fatty acid ratios resulted in increased influence of the solvent used, being more favorable for methanol.

    En este trabajo se estudia la influencia de la relación urea/ácidos grasos y de la temperatura de cristalización (con metanol y etanol como disolventes de la urea sobre las concentraciones y rendimientos en los ácidos grasos estearidónico (SA, 18:4n-3, eicosapentaenoico (EPA, 20:5n-3 y docosahexaenoico (DHA, 22:6n-3, utilizando ácidos grasos de aceite de hígado de bacalao. Las máximas concentraciones y rendimientos en SA (8,5% y 71,6%, respectivamente y en DHA (59,8% y 100% se han obtenido con metanol, una relación urea/ácidos grasos 4:1 p/p y 4°C; sin embargo, si se desean obtener altas concentraciones y rendimientos en EPA es preferible cristalizar a 28ºC (rendimiento 76%, concentración 29%. A temperaturas por debajo de -12°C también los PUFAs forman compuestos de inclusión en un porcentaje elevado, sobre todo el EPA. Mediante un análisis de la varianza se ha puesto de manifiesto que la variable con

  18. Double shell planar experiments on OMEGA

    Science.gov (United States)

    Dodd, E. S.; Merritt, E. C.; Palaniyappan, S.; Montgomery, D. S.; Daughton, W. S.; Schmidt, D. W.; Cardenas, T.; Wilson, D. C.; Loomis, E. N.; Batha, S. H.; Ping, Y.; Smalyuk, V. A.; Amendt, P. A.

    2017-10-01

    The double shell project is aimed at fielding neutron-producing capsules at the National Ignition Facility (NIF), in which an outer low-Z ablator collides with an inner high-Z shell to compress the fuel. However, understanding these targets experimentally can be challenging when compared with conventional single shell targets. Halfraum-driven planar targets at OMEGA are being used to study physics issues important to double shell implosions outside of a convergent geometry. Both VISAR and radiography through a tube have advantages over imaging through the hohlraum and double-shell capsule at NIF. A number physics issues are being studied with this platform that include 1-d and higher dimensional effects such as defect-driven hydrodynamic instabilities from engineering features. Additionally, the use of novel materials with controlled density gradients require study in easily diagnosed 1-d systems. This work ultimately feeds back into the NIF capsule platform through manufacturing tolerances set using data from OMEGA. Supported under the US DOE by the LANS, LLC under contract DE-AC52-06NA25396. LA-UR-17-25386.

  19. Omega-3 fatty acid supplementation in horses

    Directory of Open Access Journals (Sweden)

    Tanja Hess

    2014-12-01

    Full Text Available Polyunsaturated omega-3 fatty acids (n-3 PUFA are a family of essential fatty acids with many biological activities. These fatty acids are incorporated into cell membranes, changing their structural and functional characteristics. N-3 PUFA can act by modulating inflammatory responses at different levels. Omega-3 PUFA can be converted in the body to longer-chain n-3 PUFA at a limited rate and are differently converted in body systems. It appears that when specific longer-chain n-3 PUFA are desired these need to be supplemented directly in the diet. In different species some evidence indicates a potential effect on improving insulin sensitivity. Recently, a novel class of n-3 PUFA-derived anti-inflammatory mediators have been recognized, termed E-series and D-series resolvins, formed from EPA and DHA, respectively. N-3 PUFA derived resolvins and protectins are heavily involved in the resolution of inflammation. Supplementation with n-3 fatty acids in horses may help manage chronic inflammatory conditions such as osteoarthritis, equine metabolic syndrome, laminitis, and thereby help to improve longevity of sport horse.

  20. Observation of the Singly Cabibbo-Suppressed Decay D+ -> omega pi(+) and Evidence for D-0 -> omega pi(0)

    NARCIS (Netherlands)

    Ablikim, M.; Achasov, M.N.; Ai, X.C.; Albayrak, O.; Albrecht, M.; Ambrose, D.J.; Amoroso, A.; Haddadi, Z.; Kalantar-Nayestanaki, N.; Kavatsyuk, M.; Loehner, H.; Messchendorp, J.G.; Tiemens, M.

    2016-01-01

    Based on 2.93 fb(-1) e(+)e(-) collision data taken at center-of-mass energy of 3.773 GeV by the BESIII detector, we report searches for the singly Cabibbo-suppressed decays D+ -> omega pi(+) and D-0 -> omega pi(0). A double tag technique is used to measure the absolute branching fractions B(D+ ->

  1. Effect of a diet enriched with omega-6 and omega-3 fatty acids on the pig liver transcriptome

    NARCIS (Netherlands)

    Szostak, Agnieszka; Ogłuszka, Magdalena; Pas, Te Marinus F.W.; Poławska, Ewa; Urbański, Paweł; Juszczuk Kubiak, Edyta; Blicharski, Tadeusz; Pareek, Chandra Shekhar; Dunkelberger, Jenelle R.; Horbańczuk, Jarosław O.; Pierzchała, Mariusz

    2016-01-01

    The optimal ratio of omega-6 to omega-3 polyunsaturated fatty acids (PUFAs) is important for keeping the homeostasis of biological processes and metabolism, yet the underlying biological mechanism is poorly understood. The objective of this study was to identify changes in the pig liver

  2. Effect of a diet enriched with omega-6 and omega-3 fatty acids on the pig liver transcriptome

    NARCIS (Netherlands)

    Szostak, Agnieszka; Ogłuszka, Magdalena; Pas, te M.F.W.; Poławska, Ewa; Urbański, Paweł; Juszczuk-Kubiak, Edyta; Blicharski, Tadeusz; Pareek, Chandra Shekhar; Dunkelberger, Jenelle R.; Horbańczuk, Jarosław O.; Pierzchała, Mariusz

    2016-01-01

    The optimal ratio of omega-6 to omega-3 polyunsaturated fatty acids (PUFAs) is important for keeping homeostasis of biological processes and metabolism, yet the underlying biological mechanism is poorly understood. The objective of this study was to identify changes in the pig liver transcriptome

  3. Perfil de lípidos y ácidos grasos de Perna viridis, mejillón verde (Mollusca: Bivalvia en el oriente venezolano y la costa oeste de Trinidad

    Directory of Open Access Journals (Sweden)

    Tamar Koftayan

    2011-03-01

    Full Text Available Los lípidos totales fueron extraídos, identificados y cuantificados por gravimetría, mediante TLC/FID (sistema Iatroscan. Los ácidos grasos de los lípidos totales, fosfolípidos y triacilgliceroles fueron identificados y cuantificados por cromatografía de gases. Las mayores concentraciones de lípidos totales se presentaron en las muestras de Los Cedros, La Brea y Chaguaramas con valores de 7.92, 7.74 y 7.53%; respectivamente y los valores mínimos en las de La Restinga (6.08%. En la composición lípidica, las muestras de Chacopata presentaron la menor concentración de fosfolípidos (48.86% y los máximos valores de colesterol (38.87% y triacilgliceroles (12.26%, y las muestras de La Esmeralda y Río Caribe exhibieron concentraciones máximas de fosfolípidos (88.71-84.93%, respectivamente y mínimas de colesterol (6.50-4.42%. En los lípidos totales, los ácidos grasos saturados se encontraron entre 15.04 y 65.55%, con máximos en muestras de La Esmeralda y mínimos en Chacopata y los poliinsaturados estuvieron entre 7.80 y 37.18%, con máximos valores en la Brea y mínimos en la Esmeralda. En los fosfolípidos, la concentración de ácidos grasos saturados estuvo entre 38.81 y 48.68% para las muestras de Chaguaramas y Chacopata, respectivamente; los ácidos grasos poliinsaturados se encontraron entre no detectado y 34.51%, con altas concentraciones en muestras de Los Cedros (27.97% y Chaguaramas (34.51%. En los triacilgliceroles, la composición de ácidos grasos saturados variaron entre 14.27 y 53.80%, con baja concentración en Chacopata y alta concentración en La Restinga; los ácidos grasos poliinsaturados estuvieron entre 4.66 y 35.55%, con valores menores en las muestras de Chacopata (4.66% y mayores en Chaguaramas. El consumo frecuente de Perna viridis es recomendable, debido a su alto contenido de fosfolípidos y ácidos grasos insaturados.

  4. Wastewater disinfection with peracetic acid and UV; La disinfezione di acque reflue con acido peracetico e raggi ultravioletti

    Energy Technology Data Exchange (ETDEWEB)

    Caretti, C.; Lubello, C. [Florence Univ., Florence (Italy). Dipt. di Ingegneria Civile

    2001-06-01

    Was investigated the synergy between UV and peracetic acid (PAA) through a five months on-site experimental study in a pilot plant fed by the secondary effluent of the central wastewater treatment plant of Pistoia, Italy. This experiment is a part of a larger research project on advanced treatment for municipal wastewater reuse in agriculture. Because of Italy's strict limits on unrestricted wastewater reuse in agriculture (2 CFU total coliform/100 ml), a very high degree of disinfection is necessary. In the investigated experimental conditions, it has been impossible to meet such values through an exclusive use of UV irradiation (the UV unit reaches at most 4 Log inactivation). Low levels of PAA greatly enhance the decline of indicator levels, but higher unsustainable doses are required to hit the Italian limit. Through a poor amount of information on the subject was available in literature, it was tried to find out how the disinfection efficiency could improve by simultaneously using UV and PAA. It was found out that a combined treatment is satisfactory and that it is more advantage of the hydroxyl radicals formation due to the PAA photo lysis. The application of 2 ppm of PAA with an UV dose of 192 mWscm{sup -}2 is enough to meet the Italian limit. [Italian] Nel presente articolo si riportano i risultati di uno studio sulla sinergia tra acido peracetico (PAA) e raggi ultravioletti nella disinfezione delle acque reflue secondarie; le prove sono state effettuate su scala pilota, presso l'impianto centrale di Pistoia. Tale sperimentazione fa parte di un piu' ampio progetto di ricerca sulla possibilita' di riutilizzare le acque reflue a scopo irriguo; per rispettare i limiti estremamente stringenti imposti dalla normativa italiana per l'irrigazione (2 CFU Coliformi totali/100 ml, nel caso di irrigazione illimitata), e' necessario garantire efficienze di disinfezione molto elevate. Nelle condizioni sperimentali considerate, non e

  5. Power set at $\\aleph_\\omega$: On a theorem of Woodin

    OpenAIRE

    Golshani, Mohammad

    2016-01-01

    We give Woodin's original proof that if there exists a $(\\kappa+2)-$strong cardinal $\\kappa,$ then there is a generic extension of the universe in which $\\kappa=\\aleph_\\omega,$ $GCH$ holds below $\\aleph_\\omega$ and $2^{\\aleph_\\omega}=\\aleph_{\\omega+2}.$

  6. Omega-3 Polyunsaturated Fatty Acids and Heart Rate Variability

    Directory of Open Access Journals (Sweden)

    Jeppe Hagstrup Christensen

    2011-11-01

    Full Text Available Omega-3 polyunsaturated fatty acids (PUFA may modulate autonomic control of the heart because omega-3 PUFA is abundant in the brain and other nervous tissue as well as in cardiac tissue. This might partly explain why omega-3 PUFA offer some protection against sudden cardiac death (SCD. The autonomic nervous system is involved in the pathogenesis of SCD. Heart rate variability (HRV can be used as a non-invasive marker of cardiac autonomic control and a low HRV is a predictor for SCD and arrhythmic events. Studies on HRV and omega-3 PUFA have been performed in several populations such as patients with ischemic heart disease, patients with diabetes mellitus, patients with chronic renal failure, and in healthy subjects as well as in children.. The studies have demonstrated a positive association between cellular content of omega-3 PUFA and HRV and supplementation with omega-3 PUFA seems to increase HRV which could be a possible explanation for decreased risk of arrhythmic events and SCD sometimes observed after omega-3 PUFA supplementation. However, the results are not consistent and further research is needed

  7. EMBOLISMO GRASO EN UN NIÑO CON DISTROFIA MUSCULAR DE DUCHENNE Y FRACTURA BILATERAL DE FÉMUR. UNA RARA ASOCIACIÓN. Fat embolism syndrome in a child with muscular dystrophy of Duchenne type bilateral femur fracture. A rare association.

    OpenAIRE

    Enrique Vergara Amador; Fernando Galván Villamarín; Marcela Piña Quintero

    2007-01-01

    Las fracturas de fémur en pacientes que sufren de distrofia muscular de Duchenne (DMD) son frecuentes, con una incidencia entre 15-44 por ciento. El embolismo graso se presenta en fracturas de huesos largos generalmente asociado a trauma de alta energía o a lesiones extensas de tejidos blandos. El diagnóstico de embolismo graso no es tan frecuente en niños posiblemente porque cursa con presentaciones subclínicas. No existen reportes de embolismo graso asociado a distrofia muscular de Duchenne...

  8. Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids

    OpenAIRE

    Berquin, Isabelle M; Min, Younong; Wu, Ruping; Wu, Jiansheng; Perry, Donna; Cline, J. Mark; Thomas, Mike J.; Thornburg, Todd; Kulik, George; Smith, Adrienne; Edwards, Iris J.; D’Agostino, Ralph; Zhang, Hao; Wu, Hong; Kang, Jing X.

    2007-01-01

    Although a causal role of genetic alterations in human cancer is well established, it is still unclear whether dietary fat can modulate cancer risk in a predisposed population. Epidemiological studies suggest that diets rich in omega-3 polyunsaturated fatty acids reduce cancer incidence. To determine the influence of fatty acids on prostate cancer risk in animals with a defined genetic lesion, we used prostate-specific Pten-knockout mice, an immune-competent, orthotopic prostate cancer model,...

  9. Mapping QTL for Omega-3 Content in Hybrid Saline Tilapia.

    Science.gov (United States)

    Lin, Grace; Wang, Le; Ngoh, Si Te; Ji, Lianghui; Orbán, Laszlo; Yue, Gen Hua

    2017-12-04

    Tilapia is one of most important foodfish species. The low omega-3 to omega-6 fatty acid ratio in freshwater tilapia meat is disadvantageous for human health. Increasing omega-3 content is an important task in breeding to increase the nutritional value of tilapia. However, conventional breeding to increase omega-3 content is difficult and slow. To accelerate the increase of omega-3 through marker-assisted selection (MAS), we conducted QTL mapping for fatty acid contents and profiles in a F2 family of saline tilapia generated by crossing red tilapia and Mozambique tilapia. The total omega-3 content in F2 hybrid tilapia was 2.5 ± 1.0 mg/g, higher than that (2.00 mg/g) in freshwater tilapia. Genotyping by sequencing (GBS) technology was used to discover and genotype SNP markers, and microsatellites were also genotyped. We constructed a linkage map with 784 markers (151 microsatellites and 633 SNPs). The linkage map was 2076.7 cM long and consisted of 22 linkage groups. Significant and suggestive QTL for total lipid content were mapped on six linkage groups (LG3, -4, -6, -8, -13, and -15) and explained 5.8-8.3% of the phenotypic variance. QTL for omega-3 fatty acids were located on four LGs (LG11, -18, -19, and -20) and explained 5.0 to 7.5% of the phenotypic variance. Our data suggest that the total lipid and omega-3 fatty acid content were determined by multiple genes in tilapia. The markers flanking the QTL for omega-3 fatty acids can be used in MAS to accelerate the genetic improvements of these traits in salt-tolerant tilapia.

  10. Role of diets rich in omega-3 and omega-6 in the development of cancer.

    Science.gov (United States)

    Huerta-Yépez, Sara; Tirado-Rodriguez, Ana B; Hankinson, Oliver

    Over the past decade, some studies have addressed the therapeutic effects of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and the opposite effects of omega-6 (ω-6) PUFAs on several diseases, including cardiovascular disorders, diabetes, neurodegenerative diseases, and cancer. Research demonstrates the safety of these naturally occurring ingredients. Of particular interest, several studies have shown that ω-3 PUFAs possess a therapeutic role against certain types of cancer. It is also known that ω-3 PUFAs can improve the efficacy and tolerability of chemotherapy. Previous reports have indicated that suppression of nuclear factor-κB, activation of AMPK/SIRT1, modulation of cyclooxygenase (COX) activity, and up-regulation of novel anti-inflammatory lipid mediators such as protectins, maresins, and resolvins, are the main mechanisms of the antineoplastic effect of ω-3 PUFAs. In contrast, several studies have demonstrated that ω-6 PUFAs induce progression in certain types of cancer. In this review, we discuss epidemiological and experimental studies addressing the relationship between the development of some types of cancer, including colon and colorectal carcinoma, breast cancer, prostate cancer, lung cancer and neuroblastoma, and the ingestion to ω-3 and ω-6 (PUFAs). We also discuss the clinical data, addressing the therapeutic role of omega-3 PUFA against different types of cancer. Copyright © 2016 Hospital Infantil de México Federico Gómez. Publicado por Masson Doyma México S.A. All rights reserved.

  11. Role of diets rich in omega-3 and omega-6 in the development of cancer

    Directory of Open Access Journals (Sweden)

    Sara Huerta-Yépez

    2016-11-01

    Full Text Available Over the past decade, some studies have addressed the therapeutic effects of omega-3 polyunsaturated fatty acids (ω-3 PUFAs and the opposite effects of omega-6 (ω-6 PUFAs on several diseases, including cardiovascular disorders, diabetes, neurodegenerative diseases, and cancer. Research demonstrates the safety of these naturally occurring ingredients. Of particular interest, several studies have shown that ω-3 PUFAs possess a therapeutic role against certain types of cancer. It is also known that ω-3 PUFAs can improve the efficacy and tolerability of chemotherapy. Previous reports have indicated that suppression of nuclear factor-κB, activation of AMPK/SIRT1, modulation of cyclooxygenase (COX activity, and up-regulation of novel anti-inflammatory lipid mediators such as protectins, maresins, and resolvins, are the main mechanisms of the antineoplastic effect of ω-3 PUFAs. In contrast, several studies have demonstrated that ω-6 PUFAs induce progression in certain types of cancer. In this review, we discuss epidemiological and experimental studies addressing the relationship between the development of some types of cancer, including colon and colorectal carcinoma, breast cancer, prostate cancer, lung cancer and neuroblastoma, and the ingestion to ω-3 and ω-6 (PUFAs. We also discuss the clinical data, addressing the therapeutic role of omega-3 PUFA against different types of cancer.

  12. Omega spectrometer ready for SPS beams

    CERN Multimedia

    CERN PhotoLab

    1977-01-01

    Two different beams arrive into the Omega magnet: - a tagged photon beam for a charm search - experiment WA4 by the Bonn-CERN-Daresbury-Ecole Polytechnique-Glasgow-Lancaster-Manchester-Orsay-Sheffield Collaboration; - a separated hadron beam, at first for a beam-dump experiment - WA12 by the Birmingham-CERN-Ecole Polytechnique-MPI, Munich-Neuchâtel Collaboration. Beams of either negative or positive pions or kaons, protons or antiprotons, all at an energy around 40 GeV were made to impinge on a copper target where a shower of hadrons was produced and, on occasion, two muons which before detection passed through an iron absorber (not visible here). WA12 was completed in February 1977. At the centre, on top of the superconducting magnet, the hut containing the TV cameras, These observe the particle events occurring in the spark chambers in the magnet below.

  13. Implosion spectroscopy in Rugby hohlraums on OMEGA

    Science.gov (United States)

    Philippe, Franck; Tassin, Veronique; Bitaud, Laurent; Seytor, Patricia; Reverdin, Charles

    2014-10-01

    The rugby hohlraum concept has been validated in previous experiments on the OMEGA laser facility. This new hohlraum type can now be used as a well-characterized experimental platform to study indirect drive implosion, at higher radiation temperatures than would be feasible at this scale with classical cylindrical hohlraums. Recent experiments have focused on the late stages of implosion and hotspot behavior. The capsules included both a thin buried Titanium tracer layer, 0-3 microns from the inner surface, Argon dopant in the deuterium gas fuel and Germanium doped CH shells, providing a variety of spectral signatures of the plasma conditions in different parts of the target. X-ray spectroscopy and imaging were used to study compression, Rayleigh-Taylor instabilities growth at the inner surface and mix between the shell and gas.

  14. Supernova hydrodynamics on the Omega laser

    Science.gov (United States)

    Drake, R. P.; Keiter, P.; Korreck, K. E.; Dannenberg, K. K.; Robey, H. A.; Perry, T. S.; Kane, J. O.; Remington, B. A.; Wallace, R. J.; Hurricane, O. A.; Ryutov, D. D.; Knauer, J.; Teyssier, R.; Calder, A.; Rosner, R.; Fryxell, B.; Arnett, D.; Zhang, Y.; Glimm, J.; Turner, N.; Stone, J.; McCray, R.; Grove, J.

    2001-10-01

    Our experiments study mechanisms that affect the evolution of supernovae, supernova remnants, and related systems. These experiments are designed to be well scaled from astrophysical systems to the laboratory. This overview of our work will highlight our most recent results. Our work is motivated by the specific fact that numerical simulations have proven unable to reproduce certain aspects of astrophysical observations, and by the general need to provide experimental tests of modeling of hydrodynamic and radiation-hydrodynamic systems. The experiments use the Omega Laser at the Lab. for Laser Energetics, Univ. of Rochester. We have recently explored the comparison of 2D and 3D systems, the comparison of single mode and multimode systems, and the production and diagnosis of a radiative-precursor shock.

  15. FY17 LLNL Omega Experimental Programs

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, R. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Albert, F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ali, S. J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Benstead, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Chen, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Coppari, F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Doeppner, T. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Panella, A. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Fratanduono, D. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gumbrell, E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hua, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Huntington, C. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Jarrott, L. C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Jiang, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Krygier, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kuranz, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Lazicki, A. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); LePape, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Marley, E. V. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Martinez, D. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); McNaney, J. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Millot, M. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pak, A. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ping, Y. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pollock, B. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Poole, P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rinderknecht, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rubery, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Saunders, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Schneider, M. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Smith, R. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Swadling, G. F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wehrenberg, C. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Landen, O. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wan, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hsing, W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-10-26

    The Capseed campaign goal is to measure shock front velocity non-uniformities in Inertial Confinement Fusion (ICF) ablator materials and quantify the level of non-uniformity caused by intrinsic effects. This is done using the Omega High Resolution Velocimeter (OHRV) to obtain velocity maps of the optically reflecting shock front following release of the ablator material into either PMMA for the warm experiments or cryogenic deuterium for the cryo experiments. For the three half-days in FY17 the focus was twofold: complete measurements on the impact of oxygen heterogeneity and oxygen mitigation layers for glow discharge polymer (GDP), and begin measuring velocity non-uniformities on deep release from Be, GDP, and highdensity carbon (HDC) into D2 with improved velocity sensitivity.

  16. Omega-3 polyunsaturated fatty acids: photoprotective macronutrients.

    Science.gov (United States)

    Pilkington, Suzanne M; Watson, Rachel E B; Nicolaou, Anna; Rhodes, Lesley E

    2011-07-01

    Ultraviolet radiation (UVR) in sunlight has deleterious effects on skin, while behavioural changes have resulted in people gaining more sun exposure. The clinical impact includes a year-on-year increase in skin cancer incidence, and topical sunscreens alone provide an inadequate measure to combat overexposure to UVR. Novel methods of photoprotection are being targeted as additional measures, with growing interest in the potential for systemic photoprotection through naturally sourced nutrients. Omega-3 polyunsaturated fatty acids (n-3 PUFA) are promising candidates, showing potential to protect the skin from UVR injury through a range of mechanisms. In this review, we discuss the biological actions of n-3 PUFA in the context of skin protection from acute and chronic UVR overexposure and describe how emerging new technologies such as nutrigenomics and lipidomics assist our understanding of the contribution of such nutrients to skin health. © 2011 John Wiley & Sons A/S.

  17. Omega 3 fatty acids in psychiatry

    Directory of Open Access Journals (Sweden)

    Pavlović D.M.

    2013-01-01

    Full Text Available Omega-3 long-chain polyunsaturated fatty acids (ω-3 LC-PUFAs are thought to be important for normal dopaminergic, glutamatergic and serotonergic neurotransmission. Depression is less prevalent in societies with high fish consumption, and depressed patients have significantly lower red blood cell ω-3 levels. Studies with ω-3 supplementation have led to controversial results. A significantly longer remission of bipolar symptomatology has been confirmed from a high-dose DHA and EPA mixture. Greater seafood consumption per capita has been connected with a lower prevalence of bipolar spectrum disorders. Reduced levels of ω-6 and ω-3 PUFAs were found in patients with schizophrenia. [Projekat Ministarstva nauke Republike Srbije, br. 175033 i br. 175022

  18. 10 distinct stellar populations in omega Centauri.

    Science.gov (United States)

    Bellini, Andrea; Anderson, Jay; Bedin, Luigi R.; Cool, Adrienne; King, Ivan R.; van der marel, roeland p.

    2015-08-01

    We are constructing the most comprehensive catalog of photometry and proper motions ever assembled for a globular cluster. The core of omega Centauri has been imaged over 600 times through WFC3’s UVIS and IR channels for the purposes of detector calibration. There exist ~30 exposures each for 26 filters, stretching uniformly from F225W in the UV to F160W in the infrared. Furthermore, the 12-year baseline between this data and a 2002 ACS survey will more than triple both the accuracy and the number of well-measured stars compared to previous studies.This totally unprecedented complete spectral coverage for over 400,000 stars, from the red-giant branch down to the white dwarfs, provides the best chance yet to understand the multiple-population phenomenon in any globular cluster. A preliminary analysis of the color-magnitude diagrams in different bands already allows us to identify 10 distinct sequences.

  19. Perfil de ácidos grasos en carne de toretes Europeo x Cebú finalizados en pastoreo y en corral

    Directory of Open Access Journals (Sweden)

    Maribel Montero-Lagunes

    2011-01-01

    Full Text Available El objetivo fue determinar el perfil de ácidos grasos en grasa intramuscular de toretes encastados de Europeo (Bos taurus con Cebú (Bos indicus, finalizados en pastoreo y en corral. Cincuenta y dos toretes se analizaron con un ANDEVA en un arreglo factorial 2 x 2. La mitad de los animales fueron finalizados en pastoreo , siendo el pasto estrella de África [Cynodon plectostachyus (K. Schum Pilg.] la base de la alimentación, y la otra mitad en corral alimentados con 65 % de maíz, 10 % de pasta de soya, 20 % de heno, 4 % de sebo, 1 % de urea y minerales. La mitad de cada grupo consistió de toretes con más de ¾ B. taurus, y la otra mitad mayormente ¾ B. indicus . Los toretes se sacrificaron con 500 kg de peso. Se tomaron muestras del músculo Longissimus dorsi de la región de la 12a costilla. Los lípidos se analizaron por cromatografía de gases. El ácido graso más abundante (mg/g de grasa fue el C18,1 (381±16.4 seguido por el C16,0 (250±5.3 y el C18,0 (201±8.6, El contenido de C18:2, 9-cis, 11-trans fue de 6.1±0.67. C14,0 y C16,0 fueron mayores en corral, y C18,0 fue más alto en pastoreo (P<0.01. C14,0, C16,0, C18,2, C18,3 y CLA total fueron mayores (P<0.05 en B. indicus y C18,0 fue más alto (P<0.05 en B. taurus. Se concluye que el perfil de ácidos grasos en toretes cruzados de Europeo por Cebú es diferente si es finalizado en pastoreo o en corral y por el nivel de encaste.

  20. Ácidos grasos, fermentación ruminal y producción de metano, de forrajes de silvopasturas intensivas con Leucaena.

    Directory of Open Access Journals (Sweden)

    Esperanza Prieto-Manrique

    2016-06-01

    Full Text Available El objetivo del presente trabajo fue determinar el efecto de los forrajes sobre los ácidos grasos de cadena larga, fermentación ruminal y producción de metano de un sistema silvopastoril intensivo de Leucaena leucocephala. La investigación se desarrolló en el laboratorio NUTRILAB–GRICA, perteneciente a la Facultad de Ciencias Agrarias, de la Universidad de Antioquia, Medellín–Colombia, en julio del 2013. Se utilizó la técnica de producción de gas in vitro, utilizando como sustrato de fermentación las gramíneas (C. plectostachyus y/o M. maximus cv. Tanzania y leucaena (L. leucocephala, solas o en sus combinaciones, con una relación forraje:concentrado 70:30 y gramínea: leucaena 56:14, para un total de siete tratamientos. No se encontró efecto de los forrajes (p>0,05, sobre el contenido de ácido linoleico conjugado (ALC, C18:2 c9t11 o ruménico en la digesta. La inclusión de 14% de leucaena aumentó el contenido de ácido linoleico (C18:2 c9, 12 y linolénico (C18:3 c9, 12, 15 en el alimento y de transvaccénico (ATV, C18:1 t11, esteárico (C18:0, linoleico y linolénico en la digesta (p<0,05, y no afectó la cinética de fermentación, digestibilidad de la materia seca (MS, pH, total y proporción de ácidos grasos volátiles, ni redujo la producción de metano. Las gramíneas, C. plectostachyus y M. maximus, se comportaron similar en las variables evaluadas (p>0,05. Los sistemas silvopastoriles pueden ser una opción para aumentar los ácidos grasos benéficos en la leche.

  1. Anti-inflammatory effects of omega 3 and omega 6 polyunsaturated fatty acids in cardiovascular disease and metabolic syndrome.

    Science.gov (United States)

    Tortosa-Caparrós, Esther; Navas-Carrillo, Diana; Marín, Francisco; Orenes-Piñero, Esteban

    2017-11-02

    A lipid excess produces a systemic inflammation process due to tumor necrosis factor-α, interleukin-6 and C-reactive protein synthesis. Simultaneously, this fat excess promotes the appearance of insulin resistance. All this contributes to the development of atherosclerosis and increases the risk of cardiovascular diseases (CVDs). On the other hand, polyunsaturated fatty acids (PUFAs), especially eicosapentaenoic acid and docosahexaenoic acid (omega 3), and arachidonic acid (omega 6) have shown anti-inflammatory properties. Lately, an inverse relationship between omega-3 fatty acids, inflammation, obesity and CVDs has been demonstrated. To check fatty acids effect, the levels of some inflammation biomarkers have been analyzed. Leptin, adiponectin and resistin represent a group of hormones associated with the development of CVDs, obesity, type 2 diabetes mellitus and insulin resistance and are modified in obese/overweight people comparing to normal weight people. Omega-3 PUFAs have been shown to decrease the production of inflammatory mediators, having a positive effect in obesity and diabetes mellitus type-2. Moreover, they significantly decrease the appearance of CVD risk factors. Regarding omega-6 PUFA, there is controversy whether their effects are pro- or anti-inflammatory. The aim of this manuscript is to provide a comprehensive overview about the role of omega-3 and omega-6 PUFAs in CVDs and metabolic syndrome.

  2. Omega-3 Fatty Acid Formulations in Cardiovascular Disease: Dietary Supplements are Not Substitutes for Prescription Products

    OpenAIRE

    Fialkow, Jonathan

    2016-01-01

    Omega-3 fatty acid products are available as prescription formulations (icosapent ethyl, omega-3-acid ethyl esters, omega-3-acid ethyl esters A, omega-3-carboxylic acids) and dietary supplements (predominantly fish oils). Most dietary supplements and all but one prescription formulation contain mixtures of the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Products containing both EPA and DHA may raise low-density lipoprotein cholesterol (LDL-C). In clinical t...

  3. Perfil de ácidos grasos libres y características sensoriales de quesos reggianito elaborados con diferentes fermentos

    Directory of Open Access Journals (Sweden)

    Zalazar, C. A.

    2008-06-01

    Full Text Available Reggianito is the most important variety among the Argentinean hard cheeses. During its ripening period several biochemical reactions of proteins and fat are responsible for its final sensory characteristics. The fat transformations, in a first step, produce free fatty acids (FFA. In the present work, the FFA profile from C6:0 to C18:2 during ripening was evaluated. Reggianito cheeses were produced with a “wild” whey starter and with selected strains of Lactobacillus helveticus isolated from natural whey. Information from FFA profiles was processed by Principal Component Analysis (PCA and Discriminant Analysis (DA. Despite the fact that FFA levels grew continuously during ripening, no differences were found among cheeses produced with different starters. Sensory analyses did not show differences among the different cheeses produced. All cheeses were of satisfactory sensory quality. Results from this study are important for an increased knowledge of the ripening process of Reggianito cheese, considering the scarce information currently existing on this subject. At the same time, the substitution of a natural whey starter for a selected strain starter appears to be a possible advantage in order to improve and to standardize the quality of the cheese.El queso Reggianito es la variedad más importante dentro de los quesos duros fabricados en Argentina. Durante la maduración se producen innumerables reacciones bioquímicas sobre sus constituyentes, que conducen a definir las características sensoriales típicas de esta variedad de queso. Una de estas transformaciones involucra a la materia grasa originándose en una primera etapa ácidos grasos libres (AGL. En el presente trabajo se evaluó el perfil de AGL desde C6:0 hasta C18:2 a diferentes tiempos de maduración, en quesos Reggianito elaborados con suero fermento natural y con cepas seleccionadas de Lactobacillus helveticus. La información obtenida de los perfiles cromatográficos fue

  4. [The essential fatty acids omega-6 and omega-3: from their discovery to their use in therapy].

    Science.gov (United States)

    Caramia, G

    2008-04-01

    In 1929 Burr and Burr discovered the essential fatty acids omega-6 and omega-3. Since then, researchers have shown a growing interest in unsaturated essential fatty acids as they form the framework for the organism's cell membranes, particularly the neurones in the brain, are involved in the energy-transformation process, regulate the information flows between cells. Polyunsaturated fatty acids are also precursors of ''hormonal'' molecules, often with opposing effects, prostaglandins, prostacyclins, thromboxanes, leukotrienes, lipossines, resolvines, protectines that regulate immunity, platelet aggregation, inflammation, etc. They showed that raised levels of polyunsaturated fatty acids omega-3 in tissue correlate with a reduced incidence of degenerative cardiovascular disease, some mental illnesses such as depression, and neuro-degenerative diseases such as Alzheimer's. The balance between omega-3 and omega-6 acids allows the cell membranes to develop with exactly the right flexibility and fluidity, to carry messages between neurones, that is a determining factor in physical and mental well-being and has a profound influence on all the body's inflammatory responses. The results of a number of scientific studies suggest that omega-3 acids contribute to measuring and restricting inflammatory symptoms, whereas omega-6 acids (and saturated fats) give free range to inflammatory responses and amplify allergic reactions. Today in the Western countries, the ratio of omega-3 acids to omega-6 in the diet is weighted 1:10 in favour of omega-6 to up to 1:25 in some areas, while for proper functioning a 4:1 ratio of omega-6 acids to omega-3 acids is generally considered the optimum. In addition, the type of diet followed in the Western countries is very rich in saturated fats like butter and animal fats, but because of an excessive supply of these less noble fats, the cell membranes lose flexibility and this can affect the way they work. An appropriate supplement can be an

  5. Cuantificación y monitorización del hígado graso no alcohólico mediante resonancia magnética

    OpenAIRE

    Jiménez Agüero, Raúl

    2016-01-01

    133 p. + anexos Introducción:La prevalencia de la enfermedad por hígado graso no alcohólico (NAFLD, non-alcoholic fatty liver disease) está aumentando en los países desarrollados en asociación con obesidad y síndrome metabólico. Nuevas técnicas diagnósticas incruentas son necesarias para determinar de forma precisa el contenido hepático de lípidos. Hipótesis de trabajo:En este proyecto de investigación quisimos esclarecer la capacidad diagnóstica de la resonancia magnética (RM) multieco pa...

  6. Transport behaviour of commercially available 100-Omega standard resistors

    CSIR Research Space (South Africa)

    Schumacher, B

    2001-04-01

    Full Text Available Several types of commercial 100-Omega resistors can be used with the cryogenic current comparator to maintain the resistance unit, derived from the Quantized Hall Effect (QHE), and to disseminate this unit to laboratory resistance standards. Up...

  7. Secondary cardiovascular prevention: omega-3 fatty acids ineffective.

    Science.gov (United States)

    2013-09-01

    A meta-analysis of comparative clinical trials including about 20,000 patients with a history of cardiovascular disease showed that omega-3 fatty acid supplementation did not reduce the risk of a subsequent cardiovascular event.

  8. Y*, Xi * and Omega /sup -/ in production experiments

    CERN Document Server

    Hemingway, R J

    1976-01-01

    A review is given of all production experiment data relevant to the spectroscopy of Y*, Xi * and Omega /sup -/ since the previous Baryon Resonances Conference at Purdue in 1973. A short look at future prospects is appended. (27 refs).

  9. Omega-3 fatty acids in mood disorders: an overview

    Directory of Open Access Journals (Sweden)

    Young Christopher

    2003-01-01

    Full Text Available This review addresses the potential role of omega-3 fatty acids in mood disorders, from the biochemical rationale for their use to the growing body of data supporting their clinical efficacy.

  10. A study of tau decays involving eta and omega mesons

    CERN Document Server

    Buskulic, Damir; Décamp, D; Ghez, P; Goy, C; Lees, J P; Lucotte, A; Minard, M N; Nief, J Y; Odier, P; Pietrzyk, B; Casado, M P; Chmeissani, M; Crespo, J M; Delfino, M C; Efthymiopoulos, I; Fernández, E; Fernández-Bosman, M; Carrido, L; Juste, A; Martínez, M; Orteu, S; Padilla, C; Park, I C; Pascual, A; Perlas, J A; Riu, I; Sánchez, F; Teubert, F; Colaleo, A; Creanza, D; De Palma, M; Gelao, G; Girone, M; Iaselli, Giuseppe; Maggi, G; Maggi, M; Marinelli, N; Nuzzo, S; Ranieri, A; Raso, G; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Tricomi, A; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Alemany, R; Bazarko, A O; Bonvicini, G; Bright-Thomas, P G; Cattaneo, M; Comas, P; Coyle, P; Drevermann, H; Forty, Roger W; Frank, M; Hagelberg, R; Harvey, J; Janot, P; Jost, B; Kneringer, E; Knobloch, J; Lehraus, Ivan; Lutters, G; Martin, E B; Mato, P; Minten, Adolf G; Miquel, R; Mir, L M; Moneta, L; Oest, T; Pacheco, A; Pusztaszeri, J F; Ranjard, F; Rensing, P E; Rizzo, G; Rolandi, Luigi; Schlatter, W D; Schmelling, M; Schmitt, M; Schneider, O; Tejessy, W; Tomalin, I R; Venturi, A; Wachsmuth, H W; Wagner, A; Ajaltouni, Ziad J; Barrès, A; Boyer, C; Falvard, A; Gay, P; Guicheney, C; Henrard, P; Jousset, J; Michel, B; Monteil, S; Montret, J C; Pallin, D; Perret, P; Podlyski, F; Proriol, J; Rosnet, P; Rossignol, J M; Fearnley, Tom; Hansen, J B; Hansen, J D; Hansen, J R; Hansen, P H; Nilsson, B S; Rensch, B; Wäänänen, A; Kyriakis, A; Markou, C; Simopoulou, Errietta; Siotis, I; Vayaki, Anna; Zachariadou, K; Blondel, A; Bonneaud, G R; Brient, J C; Bourdon, P; Rougé, A; Rumpf, M; Valassi, Andrea; Verderi, M; Videau, H L; Candlin, D J; Parsons, M I; Focardi, E; Parrini, G; Corden, M; Georgiopoulos, C H; Jaffe, D E; Antonelli, A; Bencivenni, G; Bologna, G; Bossi, F; Campana, P; Capon, G; Casper, David William; Chiarella, V; Felici, G; Laurelli, P; Mannocchi, G; Murtas, F; Murtas, G P; Passalacqua, L; Pepé-Altarelli, M; Curtis, L; Dorris, S J; Halley, A W; Knowles, I G; Lynch, J G; O'Shea, V; Raine, C; Reeves, P; Scarr, J M; Smith, K; Teixeira-Dias, P; Thompson, A S; Thomson, F; Thorn, S; Turnbull, R M; Becker, U; Geweniger, C; Graefe, G; Hanke, P; Hansper, G; Hepp, V; Kluge, E E; Putzer, A; Schmidt, M; Sommer, J; Tittel, K; Werner, S; Wunsch, M; Abbaneo, D; Beuselinck, R; Binnie, David M; Cameron, W; Dornan, Peter J; Moutoussi, A; Nash, J; Sedgbeer, J K; Stacey, A M; Williams, M D; Dissertori, G; Girtler, P; Kuhn, D; Rudolph, G; Betteridge, A P; Bowdery, C K; Colrain, P; Crawford, G; Finch, A J; Foster, F; Hughes, G; Sloan, Terence; Williams, M I; Galla, A; Giehl, I; Greene, A M; Hoffmann, C; Jakobs, K; Kleinknecht, K; Quast, G; Renk, B; Rohne, E; Sander, H G; Van Gemmeren, P; Zeitnitz, C; Aubert, Jean-Jacques; Bencheikh, A M; Benchouk, C; Bonissent, A; Bujosa, G; Calvet, D; Carr, J; Diaconu, C A; Etienne, F; Konstantinidis, N P; Payre, P; Rousseau, D; Talby, M; Sadouki, A; Thulasidas, M; Trabelsi, K; Aleppo, M; Ragusa, F; Bauer, C; Berlich, R; Blum, Walter; Büscher, V; Dietl, H; Dydak, Friedrich; Ganis, G; Gotzhein, C; Kroha, H; Lütjens, G; Lutz, Gerhard; Männer, W; Moser, H G; Richter, R H; Rosado-Schlosser, A; Schael, S; Settles, Ronald; Seywerd, H C J; Saint-Denis, R; Stenzel, H; Wiedenmann, W; Wolf, G; Boucrot, J; Callot, O; Choi, Y; Cordier, A; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Höcker, A; Jacholkowska, A; Jacquet, M; Kim, D W; Le Diberder, F R; Lefrançois, J; Lutz, A M; Nikolic, I A; Park, H J; Schune, M H; Simion, S; Veillet, J J; Videau, I; Zerwas, D; Azzurri, P; Bagliesi, G; Batignani, G; Bettarini, S; Bozzi, C; Calderini, G; Carpinelli, M; Ciocci, M A; Ciulli, V; Dell'Orso, R; Fantechi, R; Ferrante, I; Foà, L; Forti, F; Giassi, A; Giorgi, M A; Gregorio, A; Ligabue, F; Lusiani, A; Marrocchesi, P S; Messineo, A; Palla, Fabrizio; Sanguinetti, G; Sciabà, A; Spagnolo, P; Steinberger, Jack; Tenchini, Roberto; Tonelli, G; Vannini, C; Verdini, P G; Walsh, J; Blair, G A; Bryant, L M; Cerutti, F; Chambers, J T; Gao, Y; Green, M G; Medcalf, T; Perrodo, P; Strong, J A; Von Wimmersperg-Töller, J H; Botterill, David R; Clifft, R W; Edgecock, T R; Haywood, S; Maley, P; Norton, P R; Thompson, J C; Wright, A E; Bloch-Devaux, B; Colas, P; Emery, S; Kozanecki, Witold; Lançon, E; Lemaire, M C; Locci, E; Marx, B; Pérez, P; Rander, J; Renardy, J F; Roussarie, A; Schuller, J P; Schwindling, J; Trabelsi, A; Vallage, B; Black, S N; Dann, J H; Johnson, R P; Kim, H Y; Litke, A M; McNeil, M A; Taylor, G; Booth, C N; Boswell, R; Brew, C A J; Cartwright, S L; Combley, F; Köksal, A; Lehto, M H; Newton, W M; Reeve, J; Thompson, L F; Böhrer, A; Brandt, S; Cowan, G D; Grupen, Claus; Minguet-Rodríguez, J A; Rivera, F; Saraiva, P; Smolik, L; Stephan, F; Apollonio, M; Bosisio, L; Della Marina, R; Giannini, G; Gobbo, B; Musolino, G; Rothberg, J E; Wasserbaech, S R; Armstrong, S R; Elmer, P; Feng, Z; Ferguson, D P S; Gao, Y S; González, S; Grahl, J; Greening, T C; Hayes, O J; Hu, H; McNamara, P A; Nachtman, J M; Orejudos, W; Pan, Y B; Saadi, Y; Scott, I J; Walsh, A M; Wu, X; Yamartino, J M; Zheng, M; Zobernig, G

    1997-01-01

    The 132 pb$^{-1}$ of data collected by ALEPH from 1991 to 1994 have been used to analyze $\\eta$ and $\\omega$ production in $\\tau$ decays. The following branching fractions have been measured: \\begin{eqnarray*} B(\\tau^-\\to\

  11. Estudio del contenido en ácidos grasos de aceites monovarietales elaborados a partir de aceitunas producidas en la región extremeña

    Directory of Open Access Journals (Sweden)

    Martínez Cano, Manuel

    2003-12-01

    Full Text Available Fatty acid composition of 483 samples of virgin olive oils from olives of the Extremadura varieties: Carrasqueña, Cacereña, Cornezuelo, Corniche, Morisca, Picual and Verdial de Badajoz, were analysed. After the quantitative analysis of main fatty acids, the variability according to the variety and state of ripening was studied. The discriminant analysis, taking the variety like grouping variable, explains more than 79,7 % of the variance with the two first functions and the model allows correctly classified 87,7 % of the 399 observations. The method, validated with the rest of analysed samples, improves the classification up to 89,3 %.Se ha analizado el contenido de ácidos grasos en 483 muestras de aceite de oliva virgen procedente de aceitunas de las variedades Extremeñas: Carrasqueña, Cacereña, Cornezuelo, Corniche, Morisca, Picual y Verdial de Badajoz. Cuantificados los ácidos grasos mayoritarios, se ha estudiado la variabilidad en el contenido de éstos y sus índices, atendiendo a la variedad y estado de maduración. El análisis discriminante, realizado tomando como variable de agrupación la variedad, ha permitido explicar más del 79,7 % de la varianza con las dos primeras funciones y el modelo permite clasificar correctamente el 87,5 % de las 399 muestras utilizadas. El método validado con el resto de muestras analizadas, mejora la clasificación hasta el 89,3 %.

  12. Relations between distributional, Li-Yorke and {omega} chaos

    Energy Technology Data Exchange (ETDEWEB)

    Guirao, Juan Luis Garcia [Departamento de Matematica Aplicada y Estadistica, Universidad Politecnica de Cartagena, C/Paseo Alfonso XIII, 30203-Cartagena (Region de Murcia) (Spain)]. E-mail: juan.garcia@upct.es; Lampart, Marek [Mathematical Institute at Opava, Silesian University at Opava, Na Rybnicku 1, 746 01 Opava (Czech Republic)]. E-mail: marek.lampart@math.slu.cz

    2006-05-15

    The forcing relations between notions of distributional, Li-Yorke and {omega} chaos were studied by many authors. In this paper we summarize all known connections between these three different types of chaos and fulfill the results for general compact metric spaces by the construction of a selfmap on a compact perfect set which is {omega} chaotic, not distributionally chaotic and has zero topological entropy.

  13. {Omega}/{Xi} production ratio in S-W

    Energy Technology Data Exchange (ETDEWEB)

    Abatzis, S. [Nuclear Physics Department, Athens University, GR-15771 Athens (Greece); Andrighetto, A.; Antinori, F.; Barnes, R.P.; Bayes, A.C.; Benayoun, M.; Beusch, W.; Carney, J.N.; de la Cruz, B.; Di Bari, D.; Dufey, J.P.; Davies, J.P.; Elia, D.; Evans, D.; Fini, R.; French, B.R.; Ghidini, B.; Helstrup, H.; Holme, A.K.; Jacholkowski, A.; Kahane, J.; Kinson, J.B.; Kirk, A.; Knudson, K.; Lassalle, J.C.; Lenti, V.; Leruste, P.; Manzari, V.; Narjoux, J.L.; Navach, F.; Quercigh, E.; Rossi, L.; Safarik, K.; Sene, M.; Sene, R.; Storas, T.; Vassiliadis, G.; Villalobos Baillie, O.; Volte, A.; Votruba, M.F.; Federico Antinori/CERN & Genova for WA85 Collaboration

    1995-07-20

    We have measured the ({Omega}{sup {minus}}+{bar {Omega}}{sup +})/({Xi}{sup {minus}}+{bar {Xi}}{sup +}) production ratio in central S-W collisions to be 0.8{plus_minus}0.4 at central rapidity and p{sub T}{gt}1.6 GeV/{ital c}. {copyright} 1995 {ital American} {ital Institute} {ital of} {ital Physics}.

  14. Study of omega-, eta-, eta'- and D sup - mesic nuclei

    CERN Document Server

    Tsushima, K

    2000-01-01

    Using the quark-meson coupling (QMC) model, we investigate whether omega, eta, eta' and D sup - mesons form meson-nucleus bound states. Our results suggest that one should expect to find eta- and omega-nucleus bound states in all the nuclei considered. Furthermore, it is shown that the D sup - meson will form quite narrow bound states with sup 2 sup 0 sup 8 Pb.

  15. Impact of Omega-3 Fatty Acids on the Gut Microbiota

    Science.gov (United States)

    Farinon, Barbara

    2017-01-01

    Long-term dietary habits play a crucial role in creating a host-specific gut microbiota community in humans. Despite the many publications about the effects of carbohydrates (prebiotic fibers), the impact of dietary fats, such as omega-3 polyunsaturated fatty acids (PUFAs), on the gut microbiota is less well defined. The few studies completed in adults showed some common changes in the gut microbiota after omega-3 PUFA supplementation. In particular, a decrease in Faecalibacterium, often associated with an increase in the Bacteroidetes and butyrate-producing bacteria belonging to the Lachnospiraceae family, has been observed. Coincidentally, a dysbiosis of these taxa is found in patients with inflammatory bowel disease. Omega-3 PUFAs can exert a positive action by reverting the microbiota composition in these diseases, and increase the production of anti-inflammatory compounds, like short-chain fatty acids. In addition, accumulating evidence in animal model studies indicates that the interplay between gut microbiota, omega-3 fatty acids, and immunity helps to maintain the intestinal wall integrity and interacts with host immune cells. Finally, human and animal studies have highlighted the ability of omega-3 PUFAs to influence the gut–brain axis, acting through gut microbiota composition. From these findings, the importance of the omega-3 connection to the microbiota emerges, encouraging further studies. PMID:29215589

  16. Omega-3 Fatty Acids and Skeletal Muscle Health

    Science.gov (United States)

    Jeromson, Stewart; Gallagher, Iain J.; Galloway, Stuart D. R.; Hamilton, D. Lee

    2015-01-01

    Skeletal muscle is a plastic tissue capable of adapting and mal-adapting to physical activity and diet. The response of skeletal muscle to adaptive stimuli, such as exercise, can be modified by the prior nutritional status of the muscle. The influence of nutrition on skeletal muscle has the potential to substantially impact physical function and whole body metabolism. Animal and cell based models show that omega-3 fatty acids, in particular those of marine origin, can influence skeletal muscle metabolism. Furthermore, recent human studies demonstrate that omega-3 fatty acids of marine origin can influence the exercise and nutritional response of skeletal muscle. These studies show that the prior omega-3 status influences not only the metabolic response of muscle to nutrition, but also the functional response to a period of exercise training. Omega-3 fatty acids of marine origin therefore have the potential to alter the trajectory of a number of human diseases including the physical decline associated with aging. We explore the potential molecular mechanisms by which omega-3 fatty acids may act in skeletal muscle, considering the n-3/n-6 ratio, inflammation and lipidomic remodelling as possible mechanisms of action. Finally, we suggest some avenues for further research to clarify how omega-3 fatty acids may be exerting their biological action in skeletal muscle. PMID:26610527

  17. Omega-3 Fatty Acids and Skeletal Muscle Health.

    Science.gov (United States)

    Jeromson, Stewart; Gallagher, Iain J; Galloway, Stuart D R; Hamilton, D Lee

    2015-11-19

    Skeletal muscle is a plastic tissue capable of adapting and mal-adapting to physical activity and diet. The response of skeletal muscle to adaptive stimuli, such as exercise, can be modified by the prior nutritional status of the muscle. The influence of nutrition on skeletal muscle has the potential to substantially impact physical function and whole body metabolism. Animal and cell based models show that omega-3 fatty acids, in particular those of marine origin, can influence skeletal muscle metabolism. Furthermore, recent human studies demonstrate that omega-3 fatty acids of marine origin can influence the exercise and nutritional response of skeletal muscle. These studies show that the prior omega-3 status influences not only the metabolic response of muscle to nutrition, but also the functional response to a period of exercise training. Omega-3 fatty acids of marine origin therefore have the potential to alter the trajectory of a number of human diseases including the physical decline associated with aging. We explore the potential molecular mechanisms by which omega-3 fatty acids may act in skeletal muscle, considering the n-3/n-6 ratio, inflammation and lipidomic remodelling as possible mechanisms of action. Finally, we suggest some avenues for further research to clarify how omega-3 fatty acids may be exerting their biological action in skeletal muscle.

  18. Study of the decay B0bar -> D* omega pi

    Energy Technology Data Exchange (ETDEWEB)

    Aubert, B.

    2006-04-24

    We report on a study of the decay {bar B}{sup 0} {yields} D*{sup +}{omega}{pi}{sup -} with the BABAR detector at the PEP-II B-factory at the Stanford Linear Accelerator Center. Based on a sample of 232 million B{bar B} decays, we measure the branching fraction {Beta}({bar B}{sup 0} {yields} D*{sup +}{omega}{pi}{sup -}) = (2.88 {+-} 0.21(stat.) {+-} 0.31(syst.)) x 10{sup -3}. We study the invariant mass spectrum of the {omega}{pi}{sup -} system in this decay. This spectrum is in good agreement with expectations based on factorization and the measured spectrum in {tau}{sup -} {yields} {omega}{pi}{sup -} {nu}{sub {tau}}. We also measure the polarization of the D*{sup +} as a function of the {omega}{pi}{sup -} mass. In the mass region 1.1 to 1.9 GeV we measure the fraction of longitudinal polarization of the D*{sup +} to be {Lambda}{sub L}/{Lambda} = 0.654 {+-} 0.042(stat.) {+-} 0.016(syst.). This is in agreement with the expectations from heavy-quark effective theory and factorization assuming that the decay proceeds as {bar B}{sup 0} {yields} D*{sup +}{rho}(1450), {rho}(1450) {yields} {omega}{pi}{sup -}.

  19. Impact of Omega-3 Fatty Acids on the Gut Microbiota

    Directory of Open Access Journals (Sweden)

    Lara Costantini

    2017-12-01

    Full Text Available Long-term dietary habits play a crucial role in creating a host-specific gut microbiota community in humans. Despite the many publications about the effects of carbohydrates (prebiotic fibers, the impact of dietary fats, such as omega-3 polyunsaturated fatty acids (PUFAs, on the gut microbiota is less well defined. The few studies completed in adults showed some common changes in the gut microbiota after omega-3 PUFA supplementation. In particular, a decrease in Faecalibacterium, often associated with an increase in the Bacteroidetes and butyrate-producing bacteria belonging to the Lachnospiraceae family, has been observed. Coincidentally, a dysbiosis of these taxa is found in patients with inflammatory bowel disease. Omega-3 PUFAs can exert a positive action by reverting the microbiota composition in these diseases, and increase the production of anti-inflammatory compounds, like short-chain fatty acids. In addition, accumulating evidence in animal model studies indicates that the interplay between gut microbiota, omega-3 fatty acids, and immunity helps to maintain the intestinal wall integrity and interacts with host immune cells. Finally, human and animal studies have highlighted the ability of omega-3 PUFAs to influence the gut–brain axis, acting through gut microbiota composition. From these findings, the importance of the omega-3 connection to the microbiota emerges, encouraging further studies.

  20. FEM simulation of static loading test of the Omega beam

    Science.gov (United States)

    Bílý, Petr; Kohoutková, Alena; Jedlinský, Petr

    2017-09-01

    The paper deals with a FEM simulation of static loading test of the Omega beam. Omega beam is a precast prestressed high-performance concrete element with the shape of Greek letter omega. Omega beam was designed as a self-supporting permanent formwork member for construction of girder bridges. FEM program ATENA Science was exploited for simulation of load-bearing test of the beam. The numerical model was calibrated using the data from both static loading test and tests of material properties. Comparison of load-displacement diagrams obtained from the experiment and the model was conducted. Development of cracks and crack patterns were compared. Very good agreement of experimental data and the FEM model was reached. The calibrated model can be used for design of optimized Omega beams in the future without the need of expensive loading tests. The calibrated material model can be also exploited in other types of FEM analyses of bridges constructed with the use of Omega beams, such as limit state analysis, optimization of shear connectors, prediction of long-term deflections or prediction of crack development.

  1. Omega-3 Fatty Acids and Skeletal Muscle Health

    Directory of Open Access Journals (Sweden)

    Stewart Jeromson

    2015-11-01

    Full Text Available Skeletal muscle is a plastic tissue capable of adapting and mal-adapting to physical activity and diet. The response of skeletal muscle to adaptive stimuli, such as exercise, can be modified by the prior nutritional status of the muscle. The influence of nutrition on skeletal muscle has the potential to substantially impact physical function and whole body metabolism. Animal and cell based models show that omega-3 fatty acids, in particular those of marine origin, can influence skeletal muscle metabolism. Furthermore, recent human studies demonstrate that omega-3 fatty acids of marine origin can influence the exercise and nutritional response of skeletal muscle. These studies show that the prior omega-3 status influences not only the metabolic response of muscle to nutrition, but also the functional response to a period of exercise training. Omega-3 fatty acids of marine origin therefore have the potential to alter the trajectory of a number of human diseases including the physical decline associated with aging. We explore the potential molecular mechanisms by which omega-3 fatty acids may act in skeletal muscle, considering the n-3/n-6 ratio, inflammation and lipidomic remodelling as possible mechanisms of action. Finally, we suggest some avenues for further research to clarify how omega-3 fatty acids may be exerting their biological action in skeletal muscle.

  2. A comparative study of the DG-OMEGA (DG Omega), DGII, and GAT method for the structure elucidation of a methylene-acetal linked thymine dinucleotide

    NARCIS (Netherlands)

    van Kampen, A. H. C.; Beckers, M. L. M.; Buydens, L. M. C.

    1997-01-01

    This research continues the investigation of the properties of the recently developed structure elucidation method DG-OMEGA (DG Omega). Towards this end it was applied for the structure determination of a methylene-acetal linked thymine dinucleotide. The performance of DG Omega was compared to the

  3. A study of the $\\omega\\omega$ channel produced in central pp interactions at 450 GeV/c

    CERN Document Server

    Barberis, D.; Close, F.E.; Danielsen, K.M.; Donskov, S.V.; Earl, B.C.; Evans, D.; French, B.R.; Hino, T.; Inaba, S.; Jacholkowski, A.; Jacobsen, T.; Khaustov, G.V.; Kinson, J.B.; Kirk, A.; Kondashov, A.A.; Lednev, A.A.; Lenti, V.; Minashvili, I.; Peigneux, J.P.; Romanovsky, V.; Russakovich, N.; Semenov, A.; Shagin, P.M.; Shimizu, H.; Singovsky, A.V.; Sobol, A.; Stassinaki, M.; Stroot, J.P.; Takamatsu, K.; Tsuru, T.; Villalobos Baillie, O.; Votruba, M.F.; Yasu, Y.

    2000-01-01

    The reaction pp -> pf (omega omega) ps has been studied at 450 GeV/c and a spin analysis of the omega omega channel has been performed for the first time in central production. Evidence is found for the f2(1910) in the JPC = 2++ wave with spin projection JZ = 2. This is the only state observed in central production with spin projection JZ = 2. Its dPT and phi dependencies are similar to those observed for other glueball candidates. In addition, evidence is found for a state with JPC = 4++ consistent with the f4(2300). The f0(2000), previously observed in the rho rho final state, is confirmed.

  4. Omega-3 and omega-6 content of medicinal foods for depressed patients: implications from the Iranian Traditional Medicine

    Directory of Open Access Journals (Sweden)

    Mandana Tavakkoli-Kakhki

    2014-06-01

    Full Text Available Objectives: Considering the increasing prevalence of depression in modern societies and the positive effects of omega-3 polyunsaturated fatty acids on depression, this study aims to investigate the omega-3 and omega-6 content of various foodstuffs, prescribed or prohibited by Iranian Traditional Medicine (ITM. Materials and Methods: Firstly, reliable sources of Iranian Traditional Medicine were reviewed in order to identify the prescribed and prohibited foodstuffs for depressed patients. Afterwards, according to the online database of United States Department of Agriculture (URL: http://ndb.nal.usda.gov/ndb/search/list, the ratio of linoleic acid to alpha linolenic acid (as representatives of omega-6 and omega-3, respectively was identified in each foodstuff. Finally, the ratios of omega-6 to omega-3 were compared between seven food groups of vegetables, fruits, dry goods, high protein products, dairies, breads, and spices. Results: Based on the resources of Iranian Traditional Medicine, the following foods are prescribed for depressed patients: basil, coriander, spinach, lettuce, squash, peppermint, dill, chicory, celery, beet, quince, cucumber, watermelon, grape, peach, pomegranate, banana, apple, currant, pistachio, dried fig, almond, egg, chicken, lamb, trout, milk, bread without bran,saffron, oregano, and coriander seeds. On the other hand, cabbage, eggplant, onion, garlic, broad beans, lentils, beef, whole wheat bread, and mustard are prohibited. It should be noted that omega-3 content in some prescribed foods is more than that of the prohibited ones. Conclusion: The present study showed that mint, basil, spinach, lettuce, squash, lamb, saffron, oregano, cucumber, pistachio, milk, and also wild trout can be considered as medicinal foods for depressed patients.

  5. Omega-3 and omega-6 content of medicinal foods for depressed patients: implications from the Iranian Traditional Medicine.

    Science.gov (United States)

    Tavakkoli-Kakhki, Mandana; Motavasselian, Malihe; Mosaddegh, Mahmoud; Esfahani, Mohammad Mahdi; Kamalinejad, Mohammad; Nematy, Mohsen; Eslami, Saeid

    2014-07-01

    Considering the increasing prevalence of depression in modern societies and the positive effects of omega-3 polyunsaturated fatty acids on depression, this study aims to investigate the omega-3 and omega-6 content of various foodstuffs, prescribed or prohibited by Iranian Traditional Medicine (ITM). Firstly, reliable sources of Iranian Traditional Medicine were reviewed in order to identify the prescribed and prohibited foodstuffs for depressed patients. Afterwards, according to the online database of United States Department of Agriculture (URL: http://ndb.nal.usda.gov/ndb/search/list), the ratio of linoleic acid to alpha linolenic acid (as representatives of omega-6 and omega-3, respectively) was identified in each foodstuff. Finally, the ratios of omega-6 to omega-3 were compared between seven food groups of vegetables, fruits, dry goods, high protein products, dairies, breads, and spices. Based on the resources of Iranian Traditional Medicine, the following foods are prescribed for depressed patients: basil, coriander, spinach, lettuce, squash, peppermint, dill, chicory, celery, beet, quince, cucumber, watermelon, grape, peach, pomegranate, banana, apple, currant, pistachio, dried fig, almond, egg, chicken, lamb, trout, milk, bread without bran, saffron, oregano, and coriander seeds. On the other hand, cabbage, eggplant, onion, garlic, broad beans, lentils, beef, whole wheat bread, and mustard are prohibited. It should be noted that omega-3 content in some prescribed foods is more than that of the prohibited ones. The present study showed that mint, basil, spinach, lettuce, squash, lamb, saffron, oregano, cucumber, pistachio, milk, and also wild trout can be considered as medicinal foods for depressed patients.

  6. Omega-3 and Omega-6 Fatty Acids Act as Inhibitors of the Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 Activity.

    Science.gov (United States)

    Nicolai, Eleonora; Sinibaldi, Federica; Sannino, Gianpaolo; Laganà, Giuseppina; Basoli, Francesco; Licoccia, Silvia; Cozza, Paola; Santucci, Roberto; Piro, Maria Cristina

    2017-08-01

    Polyunsaturated fatty acids have been reported to play a protective role in a wide range of diseases characterized by an increased metalloproteinases (MMPs) activity. The recent finding that omega-3 and omega-6 fatty acids exert an anti-inflammatory effect in periodontal diseases has stimulated the present study, designed to determine whether such properties derive from a direct inhibitory action of these compounds on the activity of MMPs. To this issue, we investigated the effect exerted by omega-3 and omega-6 fatty acids on the activity of MMP-2 and MMP-9, two enzymes that actively participate to the destruction of the organic matrix of dentin following demineralization operated by bacteria acids. Data obtained (both in vitro and on ex-vivo teeth) reveal that omega-3 and omega-6 fatty acids inhibit the proteolytic activity of MMP-2 and MMP-9, two enzymes present in dentin. This observation is of interest since it assigns to these compounds a key role as MMPs inhibitors, and stimulates further study to better define their therapeutic potentialities in carious decay.

  7. Omega-3s and Cardiovascular Health

    Science.gov (United States)

    DiNicolantonio, James J.; Niazi, Asfandyar K.; McCarty, Mark F.; O'Keefe, James H.; Meier, Pascal; Lavie, Carl J.

    2014-01-01

    Background Omega-3 (n-3) fatty acids have previously been shown to reduce the risk of cardiac events, cardiac death, and all-cause mortality in randomized controlled trials. However, recent data have challenged the benefits of n-3 fatty acids in the current era of optimal medical therapy. Methods We performed a literature review indicating important limitations that must be considered when interpreting the recent negative n-3 fatty acids trials. Results Our review found relative strengths and weaknesses of both the older and more recent studies, along with many possible explanations for the disparate results. The principal difference between the older and the more recent n-3 studies was a greater use of background optimal medical therapy that may have reduced the benefit from n-3s. Additionally, some of the more recent n-3 trials used relatively low doses or tested n-3 supplementation on top of a relatively high baseline intake of n-3s. Conclusion Despite the recent negative data about n-3 fatty acids, the overall evidence still supports the American Heart Association recommendation of 1 gram of eicosapentaenoic acid/docosahexaenoic acid per day for patients with coronary heart disease. PMID:25249807

  8. Omega-3 Fatty Acids and FFAR4

    Directory of Open Access Journals (Sweden)

    Da Young eOh

    2014-07-01

    Full Text Available The beneficial roles of omega-3 fatty acids (ω3-FAs on obesity, type 2 diabetes, and other metabolic diseases are well known. Most of these effects can be explained by their anti-inflammatory effects, triggered through their receptor, G protein-coupled receptor 120 (GPR120 activation. Although the whole mechanism of action is not fully described yet, it has been shown that stimulation of ω3-FA to GPR120 is followed by receptor phosphorylation. This makes GPR120 be capable of interacting to beta-arrestin-2, which in turn results in association, of beta-arrestin-2 to TAB1. This stealing of an important partaker of the inflammatory cascade, leads to interruption of the pathway, resulting in reduced inflammation. Besides this regulation of the anti-inflammatory response, GPR120 signaling also has been shown to regulate glucose homeostasis, adiposity, gastrointestinal peptide secretion, and taste preference. In this review we summarize the current knowledge about the interaction of ω3-FAs with GPR120 and the consequent opportunities for the application of ω3-FAs and possible GPR120 targets.

  9. Supernova Hydrodynamics on the Omega Laser

    Energy Technology Data Exchange (ETDEWEB)

    R. Paul Drake

    2004-01-16

    (B204)The fundamental motivation for our work is that supernovae are not well understood. Recent observations have clarified the depth of our ignorance, by producing observed phenomena that current theory and computer simulations cannot reproduce. Such theories and simulations involve, however, a number of physical mechanisms that have never been studied in isolation. We perform experiments, in compressible hydrodynamics and radiation hydrodynamics, relevant to supernovae and supernova remnants. These experiments produce phenomena in the laboratory that are believed, based on simulations, to be important to astrophysics but that have not been directly observed in either the laboratory or in an astrophysical system. During the period of this grant, we have focused on the scaling of an astrophysically relevant, radiative-precursor shock, on preliminary studies of collapsing radiative shocks, and on the multimode behavior and the three-dimensional, deeply nonlinear evolution of the Rayleigh-Taylor (RT) instability at a decelerating, embedded interface. These experiments required strong compression and decompression, strong shocks (Mach {approx}10 or greater), flexible geometries, and very smooth laser beams, which means that the 60-beam Omega laser is the only facility capable of carrying out this program.

  10. Hydrogen sulfide corrosion of weld regions in API X52 steel; Corrosion por acido sulfhidrico de las regiones de soldadura en acero API X52

    Energy Technology Data Exchange (ETDEWEB)

    Arenas-Martinez, L.F [Universidad Autonoma de Coahuila, Coahuila (Mexico)]. E-mail: fernando.arenas@uadec.edu.mx; Garcia-Cerecero, G. [Corporacion Mexicana de Investigacion en Materiales S.A. de C.V., Saltillo, Coahuila (Mexico)]. E-mail: ggarcia@comimsa.com

    2012-10-15

    The corrosion behavior of gas metal arc welding (GMAW) regions has been studied using potentiodynamic polarization and polarization resistance (LPR) techniques. Experiments were conducted in hydrogen sulfide (H{sub 2}S)-containing brine and in H{sub 2}S-free brine. Welds were made on API 5L X52 steel. Due to differences in their microstructure, chemical composition and residual stress level, weld regions exhibited different responses under H{sub 2}S corrosion. Base metal exhibited the highest corrosion rate (CR) and the most cathodic corrosion potential. [Spanish] Se estudio el comportamiento ante la corrosion de las regiones de soldadura de un cordon realizado por arco metalico con gas (GMAW) sobre un acero grado API X52 mediante las tecnicas de polarizacion potencio dinamica y resistencia a la polarizacion (LPR). Los experimentos se realizaron utilizando salmuera con 300 ppm de acido sulfhidrico (H{sub 2}S) y salmuera libre de H{sub 2}S como electrolitos. Debido a las diferencias en su microestructura, composicion quimica y el nivel de esfuerzos residuales, las regiones de soldadura mostraron diferentes respuestas a la corrosion por H{sub 2}S. El metal base exhibio la velocidad de corrosion (VC) mas alta y el potencial de corrosion mas catodico.

  11. ESTUDIO DE LA ADSORCIÓN DE PROTEÍNAS SOBRE SUPERFICIES DE ACIDO POLILÁCTICO MEDIANTE TÉCNICAS GRAVIMÉTRICAS Y ELECTROQUÍMICAS

    Directory of Open Access Journals (Sweden)

    HUGO ARMANDO ESTUPIÑAN DURAN

    2011-01-01

    Full Text Available Metodos electroquimicos fueron utilizados para promover y evaluar la adsorcion orientada de albumina y colageno sobre superficies polimericas de acido polilactico (PLA mediante la aplicacion de un sobrepotencial anodico en un rango de 0 V a 0,45 V. La adsorcion fueestudiada usando mediciones simultaneas de espectroscopia de impedancia electroquimica (EIE y microbalanza de cristal de cuarzo (QCM, en un rango de temperaturas de 25°C a 45°C, con variaciones en proteina entre 5 y 20 ¿Êg/ml en solucion buffer de fosfato de pH 7,4. Con el aumento de la concentracion de proteinas en el electrolito, disminuye la resistencia a la transferencia de carga, exhibiendo asi una mayor adsorcion sobre la superficie, ademas de aumentar la magnitud de los cambios de masa. Se mejoro la hidrofilicidad del recubrimiento, mostrando una mayor afinidad con las soluciones de colageno y por lo tanto un aumento en la biocompatibilidad debido a la activacion superficial.

  12. ANALISIS DEL CO-TRATAMIENTO PASIVO DE AGUAS RESIDUALES MUNICIPALES Y DRENAJE ACIDO DE MINAS EN CERRO RICO DE POTOSÍ, BOLIVIA

    Directory of Open Access Journals (Sweden)

    William H.J. Strosnider

    2015-01-01

    Full Text Available El drenaje acido de minas (DAM es un problema a nivel mundial. El co-tratamiento pasivo de DAM con aguas residuales municipales (ARM es una manera efectiva y de bajo costo que utiliza los nutrientes de ARM para tratar las concentraciones de metales y sulfato en DAM. Cerro Rico de Potosí, Bolivia es una de las grandes ciudades mineras en el mundo que tiene muchos problemas con el DAM. El objetivo de este estudio fue determinar velocidades de reacción de Al, Fe, Mn, Zn, y otros metales en DAM provenientes de un flujo de agua en Cerro Rico usando un sistema reactor de tres etapas. El DAM tenía un pH de 3.58, acidez de 1080 mg/L equivalente a CaCO3 conteniendo concentraciones de 12, 68, 17, y 550 mg/L de Al, Fe, Mn y Zn respectivamente. Las velocidades de reacción de Al, Fe, Mn y Zn fueron de 1.43, 2.09, 0.01 y 0.10 d-1, respectivamente.

  13. Observation of five new narrow $\\Omega_c^0$ states decaying to $\\Xi^+_c K^-$

    CERN Document Server

    Aaij, Roel; LHCb Collaboration; Adinolfi, Marco; Ajaltouni, Ziad; Akar, Simon; Albrecht, Johannes; Alessio, Federico; Alexander, Michael; Ali, Suvayu; Alkhazov, Georgy; Alvarez Cartelle, Paula; Alves Jr, Antonio Augusto; Amato, Sandra; Amerio, Silvia; Amhis, Yasmine; An, Liupan; Anderlini, Lucio; Andreassi, Guido; Andreotti, Mirco; Andrews, Jason; Appleby, Robert; Archilli, Flavio; d'Argent, Philippe; Arnau Romeu, Joan; Artamonov, Alexander; Artuso, Marina; Aslanides, Elie; Auriemma, Giulio; Baalouch, Marouen; Babuschkin, Igor; Bachmann, Sebastian; Back, John; Badalov, Alexey; Baesso, Clarissa; Baker, Sophie; Balagura, Vladislav; Baldini, Wander; Baranov, Alexander; Barlow, Roger; Barschel, Colin; Barsuk, Sergey; Barter, William; Baryshnikov, Fedor; Baszczyk, Mateusz; Batozskaya, Varvara; Batsukh, Baasansuren; Battista, Vincenzo; Bay, Aurelio; Beaucourt, Leo; Beddow, John; Bedeschi, Franco; Bediaga, Ignacio; Beiter, Andrew; Bel, Lennaert; Bellee, Violaine; Belloli, Nicoletta; Belous, Konstantin; Belyaev, Ivan; Ben-Haim, Eli; Bencivenni, Giovanni; Benson, Sean; Beranek, Sarah; Berezhnoy, Alexander; Bernet, Roland; Bertolin, Alessandro; Betancourt, Christopher; Betti, Federico; Bettler, Marc-Olivier; van Beuzekom, Martinus; Bezshyiko, Iaroslava; Bifani, Simone; Billoir, Pierre; Birnkraut, Alex; Bitadze, Alexander; Bizzeti, Andrea; Blake, Thomas; Blanc, Frederic; Blouw, Johan; Blusk, Steven; Bocci, Valerio; Boettcher, Thomas; Bondar, Alexander; Bondar, Nikolay; Bonivento, Walter; Bordyuzhin, Igor; Borgheresi, Alessio; Borghi, Silvia; Borisyak, Maxim; Borsato, Martino; Bossu, Francesco; Boubdir, Meriem; Bowcock, Themistocles; Bowen, Espen Eie; Bozzi, Concezio; Braun, Svende; Britton, Thomas; Brodzicka, Jolanta; Buchanan, Emma; Burr, Christopher; Bursche, Albert; Buytaert, Jan; Cadeddu, Sandro; Calabrese, Roberto; Calvi, Marta; Calvo Gomez, Miriam; Camboni, Alessandro; Campana, Pierluigi; Campora Perez, Daniel Hugo; Capriotti, Lorenzo; Carbone, Angelo; Carboni, Giovanni; Cardinale, Roberta; Cardini, Alessandro; Carniti, Paolo; Carson, Laurence; Carvalho Akiba, Kazuyoshi; Casse, Gianluigi; Cassina, Lorenzo; Castillo Garcia, Lucia; Cattaneo, Marco; Cavallero, Giovanni; Cenci, Riccardo; Chamont, David; Charles, Matthew; Charpentier, Philippe; Chatzikonstantinidis, Georgios; Chefdeville, Maximilien; Chen, Shanzhen; Cheung, Shu Faye; Chobanova, Veronika; Chrzaszcz, Marcin; Chubykin, Alexsei; Cid Vidal, Xabier; Ciezarek, Gregory; Clarke, Peter; Clemencic, Marco; Cliff, Harry; Closier, Joel; Coco, Victor; Cogan, Julien; Cogneras, Eric; Cogoni, Violetta; Cojocariu, Lucian; Collins, Paula; Comerma-Montells, Albert; Contu, Andrea; Cook, Andrew; Coombs, George; Coquereau, Samuel; Corti, Gloria; Corvo, Marco; Costa Sobral, Cayo Mar; Couturier, Benjamin; Cowan, Greig; Craik, Daniel Charles; Crocombe, Andrew; Cruz Torres, Melissa Maria; Cunliffe, Samuel; Currie, Robert; D'Ambrosio, Carmelo; Da Cunha Marinho, Franciole; Dall'Occo, Elena; Dalseno, Jeremy; David, Pieter; Davis, Adam; De Bruyn, Kristof; De Capua, Stefano; De Cian, Michel; De Miranda, Jussara; De Paula, Leandro; De Serio, Marilisa; De Simone, Patrizia; Dean, Cameron Thomas; Decamp, Daniel; Deckenhoff, Mirko; Del Buono, Luigi; Dembinski, Hans Peter; Demmer, Moritz; Dendek, Adam; Derkach, Denis; Deschamps, Olivier; Dettori, Francesco; Dey, Biplab; Di Canto, Angelo; Di Nezza, Pasquale; Dijkstra, Hans; Dordei, Francesca; Dorigo, Mirco; Dosil Suárez, Alvaro; Dovbnya, Anatoliy; Dreimanis, Karlis; Dufour, Laurent; Dujany, Giulio; Dungs, Kevin; Durante, Paolo; Dzhelyadin, Rustem; Dziewiecki, Michal; Dziurda, Agnieszka; Dzyuba, Alexey; Déléage, Nicolas; Easo, Sajan; Ebert, Marcus; Egede, Ulrik; Egorychev, Victor; Eidelman, Semen; Eisenhardt, Stephan; Eitschberger, Ulrich; Ekelhof, Robert; Eklund, Lars; Ely, Scott; Esen, Sevda; Evans, Hannah Mary; Evans, Timothy; Falabella, Antonio; Farley, Nathanael; Farry, Stephen; Fay, Robert; Fazzini, Davide; Ferguson, Dianne; Fernandez, Gerard; Fernandez Prieto, Antonio; Ferrari, Fabio; Ferreira Rodrigues, Fernando; Ferro-Luzzi, Massimiliano; Filippov, Sergey; Fini, Rosa Anna; Fiore, Marco; Fiorini, Massimiliano; Firlej, Miroslaw; Fitzpatrick, Conor; Fiutowski, Tomasz; Fleuret, Frederic; Fohl, Klaus; Fontana, Marianna; Fontanelli, Flavio; Forshaw, Dean Charles; Forty, Roger; Franco Lima, Vinicius; Frank, Markus; Frei, Christoph; Fu, Jinlin; Funk, Wolfgang; Furfaro, Emiliano; Färber, Christian; Gallas Torreira, Abraham; Galli, Domenico; Gallorini, Stefano; Gambetta, Silvia; Gandelman, Miriam; Gandini, Paolo; Gao, Yuanning; Garcia Martin, Luis Miguel; García Pardiñas, Julián; Garra Tico, Jordi; Garrido, Lluis; Garsed, Philip John; Gascon, David; Gaspar, Clara; Gavardi, Laura; Gazzoni, Giulio; Gerick, David; Gersabeck, Evelina; Gersabeck, Marco; Gershon, Timothy; Ghez, Philippe; Gianì, Sebastiana; Gibson, Valerie; Girard, Olivier Göran; Giubega, Lavinia-Helena; Gizdov, Konstantin; Gligorov, Vladimir; Golubkov, Dmitry; Golutvin, Andrey; Gomes, Alvaro; Gorelov, Igor Vladimirovich; Gotti, Claudio; Govorkova, Ekaterina; Graciani Diaz, Ricardo; Granado Cardoso, Luis Alberto; Graugés, Eugeni; Graverini, Elena; Graziani, Giacomo; Grecu, Alexandru; Greim, Roman; Griffith, Peter; Grillo, Lucia; Gruberg Cazon, Barak Raimond; Grünberg, Oliver; Gushchin, Evgeny; Guz, Yury; Gys, Thierry; Göbel, Carla; Hadavizadeh, Thomas; Hadjivasiliou, Christos; Haefeli, Guido; Haen, Christophe; Haines, Susan; Hamilton, Brian; Han, Xiaoxue; Hansmann-Menzemer, Stephanie; Harnew, Neville; Harnew, Samuel; Harrison, Jonathan; Hatch, Mark; He, Jibo; Head, Timothy; Heister, Arno; Hennessy, Karol; Henrard, Pierre; Henry, Louis; van Herwijnen, Eric; Heß, Miriam; Hicheur, Adlène; Hill, Donal; Hombach, Christoph; Hopchev, Plamen Hristov; Huard, Zachary; Hulsbergen, Wouter; Humair, Thibaud; Hushchyn, Mikhail; Hutchcroft, David; Idzik, Marek; Ilten, Philip; Jacobsson, Richard; Jalocha, Pawel; Jans, Eddy; Jawahery, Abolhassan; Jiang, Feng; John, Malcolm; Johnson, Daniel; Jones, Christopher; Joram, Christian; Jost, Beat; Jurik, Nathan; Kandybei, Sergii; Karacson, Matthias; Kariuki, James Mwangi; Karodia, Sarah; Kecke, Matthieu; Kelsey, Matthew; Kenzie, Matthew; Ketel, Tjeerd; Khairullin, Egor; Khanji, Basem; Khurewathanakul, Chitsanu; Kirn, Thomas; Klaver, Suzanne; Klimaszewski, Konrad; Klimkovich, Tatsiana; Koliiev, Serhii; Kolpin, Michael; Komarov, Ilya; Kopecna, Renata; Koppenburg, Patrick; Kosmyntseva, Alena; Kotriakhova, Sofia; Kozachuk, Anastasiia; Kozeiha, Mohamad; Kravchuk, Leonid; Kreps, Michal; Krokovny, Pavel; Kruse, Florian; Krzemien, Wojciech; Kucewicz, Wojciech; Kucharczyk, Marcin; Kudryavtsev, Vasily; Kuonen, Axel Kevin; Kurek, Krzysztof; Kvaratskheliya, Tengiz; Lacarrere, Daniel; Lafferty, George; Lai, Adriano; Lanfranchi, Gaia; Langenbruch, Christoph; Latham, Thomas; Lazzeroni, Cristina; Le Gac, Renaud; van Leerdam, Jeroen; Leflat, Alexander; Lefrançois, Jacques; Lefèvre, Regis; Lemaitre, Florian; Lemos Cid, Edgar; Leroy, Olivier; Lesiak, Tadeusz; Leverington, Blake; Li, Tenglin; Li, Yiming; Li, Zhuoming; Likhomanenko, Tatiana; Lindner, Rolf; Lionetto, Federica; Liu, Xuesong; Loh, David; Longstaff, Iain; Lopes, Jose; Lucchesi, Donatella; Lucio Martinez, Miriam; Luo, Haofei; Lupato, Anna; Luppi, Eleonora; Lupton, Oliver; Lusiani, Alberto; Lyu, Xiao-Rui; Machefert, Frederic; Maciuc, Florin; Maev, Oleg; Maguire, Kevin; Malde, Sneha; Malinin, Alexander; Maltsev, Timofei; Manca, Giulia; Mancinelli, Giampiero; Manning, Peter Michael; Maratas, Jan; Marchand, Jean François; Marconi, Umberto; Marin Benito, Carla; Marinangeli, Matthieu; Marino, Pietro; Marks, Jörg; Martellotti, Giuseppe; Martin, Morgan; Martinelli, Maurizio; Martinez Santos, Diego; Martinez Vidal, Fernando; Martins Tostes, Danielle; Massacrier, Laure Marie; Massafferri, André; Matev, Rosen; Mathad, Abhijit; Mathe, Zoltan; Matteuzzi, Clara; Mauri, Andrea; Maurice, Emilie; Maurin, Brice; Mazurov, Alexander; McCann, Michael; McNab, Andrew; McNulty, Ronan; Meadows, Brian; Meier, Frank; Melnychuk, Dmytro; Merk, Marcel; Merli, Andrea; Michielin, Emanuele; Milanes, Diego Alejandro; Minard, Marie-Noelle; Mitzel, Dominik Stefan; Mogini, Andrea; Molina Rodriguez, Josue; Monroy, Igancio Alberto; Monteil, Stephane; Morandin, Mauro; Morello, Michael Joseph; Morgunova, Olga; Moron, Jakub; Morris, Adam Benjamin; Mountain, Raymond; Muheim, Franz; Mulder, Mick; Mussini, Manuel; Müller, Dominik; Müller, Janine; Müller, Katharina; Müller, Vanessa; Naik, Paras; Nakada, Tatsuya; Nandakumar, Raja; Nandi, Anita; Nasteva, Irina; Needham, Matthew; Neri, Nicola; Neubert, Sebastian; Neufeld, Niko; Neuner, Max; Nguyen, Thi Dung; Nguyen-Mau, Chung; Nieswand, Simon; Niet, Ramon; Nikitin, Nikolay; Nikodem, Thomas; Nogay, Alla; Novoselov, Alexey; O'Hanlon, Daniel Patrick; Oblakowska-Mucha, Agnieszka; Obraztsov, Vladimir; Ogilvy, Stephen; Oldeman, Rudolf; Onderwater, Gerco; Otalora Goicochea, Juan Martin; Owen, Patrick; Oyanguren, Maria Aranzazu; Pais, Preema Rennee; Palano, Antimo; Palutan, Matteo; Papanestis, Antonios; Pappagallo, Marco; Pappalardo, Luciano; Pappenheimer, Cheryl; Parker, William; Parkes, Christopher; Passaleva, Giovanni; Pastore, Alessandra; Patel, Mitesh; Patrignani, Claudia; Pearce, Alex; Pellegrino, Antonio; Penso, Gianni; Pepe Altarelli, Monica; Perazzini, Stefano; Perret, Pascal; Pescatore, Luca; Petridis, Konstantinos; Petrolini, Alessandro; Petrov, Aleksandr; Petruzzo, Marco; Picatoste Olloqui, Eduardo; Pietrzyk, Boleslaw; Pikies, Malgorzata; Pinci, Davide; Pistone, Alessandro; Piucci, Alessio; Placinta, Vlad-Mihai; Playfer, Stephen; Plo Casasus, Maximo; Poikela, Tuomas; Polci, Francesco; Poli Lener, Marco; Poluektov, Anton; Polyakov, Ivan; Polycarpo, Erica; Pomery, Gabriela Johanna; Ponce, Sebastien; Popov, Alexander; Popov, Dmitry; Popovici, Bogdan; Poslavskii, Stanislav; Potterat, Cédric; Price, Eugenia; Prisciandaro, Jessica; Prouve, Claire; Pugatch, Valery; Puig Navarro, Albert; Punzi, Giovanni; Qian, Chen; Qian, Wenbin; Quagliani, Renato; Rachwal, Bartolomiej; Rademacker, Jonas; Rama, Matteo; Ramos Pernas, Miguel; Rangel, Murilo; Raniuk, Iurii; Ratnikov, Fedor; Raven, Gerhard; Redi, Federico; Reichert, Stefanie; dos Reis, Alberto; Remon Alepuz, Clara; Renaudin, Victor; Ricciardi, Stefania; Richards, Sophie; Rihl, Mariana; Rinnert, Kurt; Rives Molina, Vicente; Robbe, Patrick; Rodrigues, Ana Barbara; Rodrigues, Eduardo; Rodriguez Lopez, Jairo Alexis; Rodriguez Perez, Pablo; Rogozhnikov, Alexey; Roiser, Stefan; Rollings, Alexandra Paige; Romanovskiy, Vladimir; Romero Vidal, Antonio; Ronayne, John William; Rotondo, Marcello; Rudolph, Matthew Scott; Ruf, Thomas; Ruiz Valls, Pablo; Saborido Silva, Juan Jose; Sadykhov, Elnur; Sagidova, Naylya; Saitta, Biagio; Salustino Guimaraes, Valdir; Sanchez Gonzalo, David; Sanchez Mayordomo, Carlos; Sanmartin Sedes, Brais; Santacesaria, Roberta; Santamarina Rios, Cibran; Santimaria, Marco; Santovetti, Emanuele; Sarti, Alessio; Satriano, Celestina; Satta, Alessia; Saunders, Daniel Martin; Savrina, Darya; Schael, Stefan; Schellenberg, Margarete; Schiller, Manuel; Schindler, Heinrich; Schlupp, Maximilian; Schmelling, Michael; Schmelzer, Timon; Schmidt, Burkhard; Schneider, Olivier; Schopper, Andreas; Schreiner, HF; Schubert, Konstantin; Schubiger, Maxime; Schune, Marie Helene; Schwemmer, Rainer; Sciascia, Barbara; Sciubba, Adalberto; Semennikov, Alexander; Sergi, Antonino; Serra, Nicola; Serrano, Justine; Sestini, Lorenzo; Seyfert, Paul; Shapkin, Mikhail; Shapoval, Illya; Shcheglov, Yury; Shears, Tara; Shekhtman, Lev; Shevchenko, Vladimir; Siddi, Benedetto Gianluca; Silva Coutinho, Rafael; Silva de Oliveira, Luiz Gustavo; Simi, Gabriele; Simone, Saverio; Sirendi, Marek; Skidmore, Nicola; Skwarnicki, Tomasz; Smith, Eluned; Smith, Iwan Thomas; Smith, Jackson; Smith, Mark; Soares Lavra, Lais; Sokoloff, Michael; Soler, Paul; Souza De Paula, Bruno; Spaan, Bernhard; Spradlin, Patrick; Sridharan, Srikanth; Stagni, Federico; Stahl, Marian; Stahl, Sascha; Stefko, Pavol; Stefkova, Slavomira; Steinkamp, Olaf; Stemmle, Simon; Stenyakin, Oleg; Stevens, Holger; Stoica, Sabin; Stone, Sheldon; Storaci, Barbara; Stracka, Simone; Stramaglia, Maria Elena; Straticiuc, Mihai; Straumann, Ulrich; Sun, Liang; Sutcliffe, William; Swientek, Krzysztof; Syropoulos, Vasileios; Szczekowski, Marek; Szumlak, Tomasz; T'Jampens, Stephane; Tayduganov, Andrey; Tekampe, Tobias; Tellarini, Giulia; Teubert, Frederic; Thomas, Eric; van Tilburg, Jeroen; Tilley, Matthew James; Tisserand, Vincent; Tobin, Mark; Tolk, Siim; Tomassetti, Luca; Tonelli, Diego; Topp-Joergensen, Stig; Toriello, Francis; Tourinho Jadallah Aoude, Rafael; Tournefier, Edwige; Tourneur, Stephane; Trabelsi, Karim; Traill, Murdo; Tran, Minh Tâm; Tresch, Marco; Trisovic, Ana; Tsaregorodtsev, Andrei; Tsopelas, Panagiotis; Tully, Alison; Tuning, Niels; Ukleja, Artur; Ustyuzhanin, Andrey; Uwer, Ulrich; Vacca, Claudia; Vagnoni, Vincenzo; Valassi, Andrea; Valat, Sebastien; Valenti, Giovanni; Vazquez Gomez, Ricardo; Vazquez Regueiro, Pablo; Vecchi, Stefania; van Veghel, Maarten; Velthuis, Jaap; Veltri, Michele; Veneziano, Giovanni; Venkateswaran, Aravindhan; Verlage, Tobias Anton; Vernet, Maxime; Vesterinen, Mika; Viana Barbosa, Joao Vitor; Viaud, Benoit; Vieira, Daniel; Vieites Diaz, Maria; Viemann, Harald; Vilasis-Cardona, Xavier; Vitti, Marcela; Volkov, Vladimir; Vollhardt, Achim; Voneki, Balazs; Vorobyev, Alexey; Vorobyev, Vitaly; Voß, Christian; de Vries, Jacco; Vázquez Sierra, Carlos; Waldi, Roland; Wallace, Charlotte; Wallace, Ronan; Walsh, John; Wang, Jianchun; Ward, David; Wark, Heather Mckenzie; Watson, Nigel; Websdale, David; Weiden, Andreas; Whitehead, Mark; Wicht, Jean; Wilkinson, Guy; Wilkinson, Michael; Williams, Mark Richard James; Williams, Matthew; Williams, Mike; Williams, Timothy; Wilson, Fergus; Wimberley, Jack; Winn, Michael Andreas; Wishahi, Julian; Wislicki, Wojciech; Witek, Mariusz; Wormser, Guy; Wotton, Stephen; Wraight, Kenneth; Wyllie, Kenneth; Xie, Yuehong; Xing, Zhou; Xu, Zhirui; Yang, Zhenwei; Yang, Zishuo; Yao, Yuezhe; Yin, Hang; Yu, Jiesheng; Yuan, Xuhao; Yushchenko, Oleg; Zarebski, Kristian Alexander; Zavertyaev, Mikhail; Zhang, Liming; Zhang, Yanxi; Zhelezov, Alexey; Zheng, Yangheng; Zhu, Xianglei; Zhukov, Valery; Zucchelli, Stefano

    2017-05-02

    The $\\Xi^+_c K^-$ mass spectrum is studied with a sample of $pp$ collision data corresponding to an integrated luminosity of 3.3 fb$^{-1}$, collected by the LHCb experiment. The $\\Xi^+_c$ is reconstructed in the decay mode $pK^- \\pi^+$. Five new, narrow excited $\\Omega_c^0$ states are observed: the $\\Omega_c (3000)^0$, $\\Omega_c (3050)^0$, $\\Omega_c (3066)^0$, $\\Omega_c (3090)^0$, and $\\Omega_c (3119)^0$. Measurements of their masses and widths are reported.

  14. Helping women to good health: breast cancer, omega-3/omega-6 lipids, and related lifestyle factors.

    Science.gov (United States)

    de Lorgeril, Michel; Salen, Patricia

    2014-03-27

    In addition to genetic predisposition and sex hormone exposure, physical activity and a healthy diet play important roles in breast cancer (BC). Increased intake of omega-3 fatty acids (n-3) associated with decreased omega-6 (n-6), resulting in a higher n-3/n-6 ratio compared with the western diet, are inversely associated with BC risk, as shown by Yang et al. in their meta-analysis in BMC Cancer. High consumption of polyphenols and organic foods increase the n-3/n-6 ratio, and in turn may decrease BC risk. Intake of high fiber foods and foods with low glycemic index decreases insulin resistance and diabetes risk, and in turn may decrease BC risk. The modernized Mediterranean diet is an effective strategy for combining these recommendations, and this dietary pattern reduces overall cancer risk and specifically BC risk. High-risk women should also eliminate environmental endocrine disruptors, including those from foods. Drugs that decrease the n-3/n-6 ratio or that are suspected of increasing BC or diabetes risk should be used with great caution by high-risk women and women wishing to decrease their BC risk.Please see related article: http://www.biomedcentral.com/1471-2407/14/105/abstract.

  15. Efecto de diferentes métodos de extracción sobre el perfil de ácidos grasos en el aceite de aguacate (Persea americana Mill. var. Hass)

    OpenAIRE

    Arturo Martínez Zavala; Joel Díaz Reyes; María Elena Ramos Cassellis; Judith Coyotl Huerta; Fernando López Valdez; José Alberto Ariza Ortega

    2011-01-01

    El objetivo de este estudio fue evaluar la posible formación de ácidos grasos trans (AGT) en el aceite de aguacate, extraído con disolvente (hexano), con y sin calor, y por centrifugación. Para analizar el aceite se emplearon índices químicos, y para la identificación y cuantificación de los ácidos grasos se utilizó Espectroscopía de Infrarrojo con Transformada de Fourier (EITF), en la región media de 400 a 4000 cm-1 y cromatografía de gases. En los resultados del análisis por EITF se demostr...

  16. Fatty acid composition of the pollen lipids of Cycas revoluta Thunb; Composición en ácidos grasos de los lípidos del polen de palmeras Cycas revoluta

    Energy Technology Data Exchange (ETDEWEB)

    Sidorov, R.A.; Kuznetsova, E.I.; Pchelkin, V.P.; Zhukov, A.V.; Gorshkova, E.N.; Tsydendambaev, V.D.

    2016-07-01

    The fatty acid (FA) composition of total extractable and non extractable with chloroform lipids of C. revoluta pollen was determined. Among other minor FAs, unusual Δ5 polymethylene-interrupted FA, Δ5, 11-octadecadienoic acid was found. This FA was found in the seed lipids of C. revoluta earlier, but it was discovered for the first time in pollen lipids. [Spanish] Se determinó la composición en ácidos grasos (AG) de los lípidos totales extraíbles y no extraíbles con cloroformo del polen de la palmera C. revoluta. Entre otros ácidos grasos menores se encontró un AG Δ5 inusual, el ácido octadecadienoico, Δ5,11-polimetilen-interrumpido. Este AG ya fue descrito en los lípidos de semillas de C. revoluta, pero en los lípidos del polen es la primera vez que se describen.

  17. The Omega-Infinity Limit of Single Spikes

    CERN Document Server

    Axenides, Minos; Linardopoulos, Georgios

    A new infinite-size limit of strings in RxS2 is presented. The limit is obtained from single spike strings by letting their angular velocity omega become infinite. We derive the energy-momenta relation of omega-infinity single spikes as their linear velocity v-->1 and their angular momentum J-->1. Generally, the v-->1, J-->1 limit of single spikes is singular and has to be excluded from the spectrum and be studied separately. We discover that the dispersion relation of omega-infinity single spikes contains logarithms in the limit J-->1. This result is somewhat surprising, since the logarithmic behavior in the string spectra is typically associated with their motion in non-compact spaces such as AdS. Omega-infinity single spikes seem to completely cover the surface of the 2-sphere they occupy, so that they may essentially be viewed as some sort of "brany strings". A proof of the sphere-filling property of omega-infinity single spikes is given in the appendix.

  18. Observation of the $Omega_{c}$ Charmed Baryon at CLEO

    CERN Document Server

    Ahmed, S; Athar, S B; Jian, L; Ling, L; Saleem, M; Timm, S; Wappler, F; Anastassov, A; Duboscq, J E; Eckhart, E; Gan, K K; Gwon, C; Hart, T; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pedlar, T K; Schwarthoff, H; Thayer, J B; Von Törne, E; Zoeller, M M; Richichi, S J; Severini, H; Skubic, P L; Undrus, A; Chen, S; Fast, J; Hinson, J W; Lee, J; Miller, D H; Shibata, E I; Shipsey, I P J; Pavlunin, V; Cronin-Hennessy, D; Lyon, A L; Thorndike, E H; Jessop, C P; Perl, Martin Lewis; Savinov, V; Zhou, X; Coan, T E; Fadeev, V; Maravin, Y; Narsky, I; Stroynowski, R; Ye, J; Wlodek, T; Artuso, M; Ayad, R; Boulahouache, C; Bukin, K; Dambasuren, E; Karamov, S; Majumder, G; Moneti, G C; Mountain, R; Schuh, S; Skwarnicki, T; Stone, S; Viehhauser, G; Wang, J C; Wolf, A; Wu, J; Kopp, S E; Mahmood, A H; Csorna, S E; Danko, I; McLean, K W; Marka, S; Xu, Z; Godang, R; Kinoshita, K; Lai, I C; Schrenk, S; Bonvicini, G; Cinabro, D; McGee, S; Perera, L P; Zhou, G J; Lipeles, E; Pappas, S P; Schmidtler, M; Shapiro, A; Sun, W M; Weinstein, A J; Würthwein, F; Jaffe, D E; Masek, G E; Paar, H P; Potter, E M; Prell, S; Asner, D M; Eppich, A; Hill, T S; Morrison, R J; Briere, R A; Chen, G P; Behrens, B H; Ford, W T; Gritsan, A; Roy, J D; Smith, J G; Alexander, J P; Baker, R; Bebek, C; Berger, B E; Berkelman, K; Blanc, F; Boisvert, V; Cassel, David G; Dickson, M; Drell, P S; Ecklund, K M; Ehrlich, R; Foland, A D; Gaidarev, P B; Gibbons, L K; Gittelman, B; Gray, S W; Hartill, D L; Heltsley, B K; Hopman, P I; Jones, C D; Kreinick, D L; Lohner, M; Magerkurth, A; Meyer, T O; Mistry, N B; Nordberg, E; Patterson, J R; Peterson, D; Riley, D; Thayer, J G; Urner, D; Valant-Spaight, B L; Warburton, A; Avery, P; Prescott, C; Rubiera, A I; Yelton, J; Zheng, J; Brandenburg, G; Ershov, A; Gao, Y S; Kim, D Y J; Wilson, R; Browder, T E; Li, Y; Rodríguez, J L; Yamamoto, H; Bergfeld, T; Eisenstein, B I; Ernst, J; Gladding, G E; Gollin, G D; Hans, R M; Johnson, E; Karliner, I; Marsh, M A; Palmer, M; Plager, C; Sedlack, C; Selen, M; Thaler, J J; Williams, J; Edwards, K W; Janicek, R; Patel, P M; Sadoff, A J; Ammar, R; Bean, A; Besson, D; Davis, R; Kwak, N; Zhao, X; Anderson, S; Frolov, V V; Kubota, Y; Lee, S J; Mahapatra, R; O'Neill, J J; Poling, R A; Riehle, T; Smith, A; Stepaniak, C J; Urheim, J

    2000-01-01

    The CLEO detector at the CESR collider has used 13.7 fb^{-1} to search for the production of Omega_c (css-ground state) in e^{+}e^{-} collisions at sqrt{s} = 10.6 GeV The modes used to study the Omega_c are Omega- pi+, Omega- pi+ pi0, Xi- K- pi+ pi+, Xi0 K- pi+, and Omega- pi+ pi+ pi-. We observe 40.4 +- 9.0(stat) combined events at a mass of 2694.6 +- 2.6(stat) +- 2.4(syst) MeV. We have also measured the \\sigma * Br of the above modes for xp > 0.5 to be 11.3 +- 3.9 +- 2.3 fb, 47.6 +- 18.0 +- 2.8 fb, 45.1 +- 23.2 +- 4.1 fb, 18.2 +- 10.6 +- 3.8 fb, and <5.1 fb @ 90 % CL, respectively.

  19. Exclusive Backward-Angle Omega Meson Electroproduction

    Energy Technology Data Exchange (ETDEWEB)

    Wenliang, Li [Univ. of Regina, Regina, SK (Canada)

    2017-10-01

    Exclusive meson electroproduction at different squared four-momenta of the exchanged virtual photon, Q2 , and at different four-momentum transfers, t and u, can be used to probe QCD's transition from hadronic degrees of freedom at the long distance scale to quark-gluon degrees of freedom at the short distance scale. Backward-angle meson electroproduction was previously ignored, but is anticipated to offer complimentary information to conventional forward-angle meson electroproduction studies on nucleon structure. This work is a pioneering study of backward-angle ω cross sections through the exclusive 1H(e, e'p)ω reaction using the missing mass reconstruction technique. The extracted cross sections are separated into the transverse (T), longitudinal (L), and LT, TT interference terms. The analyzed data were part of experiment E01-004 (Fπ-2), which used 2.6-5.2 GeV electron beams and HMS+SOS spectrometers in Jefferson Lab Hall C. The primary objective was to detect coincidence π in the forward-angle, where the backward-angle omega events were fortuitously detected. The experiment has central Q2 values of 1.60 and 2.45 GeV2 , at W = 2.21 GeV. There was significant coverage in phi and epsilon, which allowed separation of σT,L,LT,TT . The data set has a unique u coverage of -u ~ 0, which corresponds to -t > 4 GeV2 . The separated σT result suggest a flat ~ 1/Q1.33±1.21 dependence, whereas sigma_L seems to hold a stronger 1/Q9.43±6.28 dependence. The σL/σT ratio indicate σT dominance at Q2 = 2.45 GeV2 at the ~90% confidence level. After translating the results into the -t space of the published CLAS data, our data show evidence of a backward-angle omega electroproduction peak at both Q2 settings. Previously, this phenomenon showing both forward and backward-angle peaks was only observed in the meson

  20. Hubble Space Telescope Image of Omega Nebula

    Science.gov (United States)

    2002-01-01

    This sturning image, taken by the newly installed Advanced Camera for Surveys (ACS) aboard the Hubble Space Telescope (HST), is an image of the center of the Omega Nebula. It is a hotbed of newly born stars wrapped in colorful blankets of glowing gas and cradled in an enormous cold, dark hydrogen cloud. The region of nebula shown in this photograph is about 3,500 times wider than our solar system. The nebula, also called M17 and the Swan Nebula, resides 5,500 light-years away in the constellation Sagittarius. The Swan Nebula is illuminated by ultraviolet radiation from young, massive stars, located just beyond the upper-right corner of the image. The powerful radiation from these stars evaporates and erodes the dense cloud of cold gas within which the stars formed. The blistered walls of the hollow cloud shine primarily in the blue, green, and red light emitted by excited atoms of hydrogen, nitrogen, oxygen, and sulfur. Particularly striking is the rose-like feature, seen to the right of center, which glows in the red light emitted by hydrogen and sulfur. As the infant stars evaporate the surrounding cloud, they expose dense pockets of gas that may contain developing stars. One isolated pocket is seen at the center of the brightest region of the nebula. Other dense pockets of gas have formed the remarkable feature jutting inward from the left edge of the image. The color image is constructed from four separate images taken in these filters: blue, near infrared, hydrogen alpha, and doubly ionized oxygen. Credit: NASA, H. Ford (JHU), G. Illingworth (USCS/LO), M. Clampin (STScI), G. Hartig (STScI), the ACS Science Team, and ESA.

  1. La importancia de los ácidos grasos en la leche materna y en las fórmulas lácteas

    Directory of Open Access Journals (Sweden)

    Vega, S.

    2012-06-01

    Full Text Available The best choice for feeding the newborn child is breast milk, and when it is not possible to breastfeed a baby, the breast milk is replaced by lacteal formula, which is why numerous studies focus their attention on the analysis of the diverse components of baby formula as well as functions in the breastfed baby. Fatty acids are components of great nutritional importance in the fetus and in the newborn child. Nowadays it is estimated that the fetus, during the last trimester of the gestational period and the newborn child, during the first six months of life, need a great contribution of araquidonic and docosahexaenoic acids, due to the fact that the speed of transformation of the predecessors to the hepatic level are not sufficient to cover the metabolic requirements of these fatty acids and it is the mother who contributes them through placental transport during gestation and her milk during lactation. The Organization of Food and Agriculture (FAO, the World Health Organization (WHO, the European Society of Gastroenterology, Hepatology and Pediatric Nutrition (ESPGHAN and the American Academy of Pediatrics recommend that lacteal formula imitate the composition of the breast milk, especially in the fatty polyunsaturated acids (PUFA.

    El alimento natural por excelencia para el recién nacido es la leche materna, cuando no es posible darla se sustituye por fórmulas lácteas, por lo que numerosos estudios enfocan su interés en el análisis de los diversos componentes de éstas, y sus funciones en el lactante. Los ácidos grasos son componentes de gran importancia nutricional tanto en el feto como en el recién nacido. Actualmente se estima que el feto, durante el último tercio del periodo gestacional y el recién nacido, durante los primeros seis meses de vida, requieren un gran aporte de ácidos araquidónico y docosahexaenoico, debido a que la velocidad de transformación de los precursores a nivel hepático no son suficientes para

  2. The Sixth Omega Laser Facility Users Group Workshop

    Energy Technology Data Exchange (ETDEWEB)

    Petrasso, R. D.

    2014-10-01

    A capacity gathering of over 100 researchers from 25 universities and laboratories met at the Laboratory for Laser Energetics (LLE) for the Sixth Omega Laser Facility Users Group (OLUG) workshop. The purpose of the 2.5-day workshop was to facilitate communications and exchanges among individual OMEGA users, and between users and the LLE management; to present ongoing and proposed research; to encourage research opportunities and collaborations that could be undertaken at the Omega Laser Facility and in a complementary fashion at other facilities [such as the National Ignition Facility (NIF) or the Laboratoire pour l’Utilisation des Lasers Intenses (LULI)]; to provide an opportunity for students, postdoctoral fellows, and young researchers to present their research in an informal setting; and to provide feedback from the users to LLE management about ways to improve and keep the facility and future experimental campaigns at the cutting edge.

  3. Pathophysiological role of omega pore current in channelopathies

    Directory of Open Access Journals (Sweden)

    Karin eJurkat-Rott

    2012-06-01

    Full Text Available In voltage-gated cation channels, a recurrent pattern for mutations is the neutralization of positively charged residues in the voltage-sensing S4 transmembrane segments. These mutations cause dominant ion channelopathies affecting many tissues such as brain, heart, and skeletal muscle. Recent studies suggest that the pathogenesis of associated phenotypes is not limited to alterations in the gating of the ion-conducting alpha pore. Instead, aberrant so-called omega currents facilitated by the movement of the S4 segments during activation and during recovery are thought to cause symptoms. Surprisingly, these omega currents display uni- or bi-directionality and conduct cations with varying ion selectivity. Additionally, the voltage-sensitivity enables the channels to conduct different omega currents in the various voltage ranges. This review gives an overview of voltage sensor channelopathies in general and focuses on pathogenesis of skeletal muscle S4 disorders for which current knowledge is most advanced.

  4. Omega-3 Fatty Acids Moderate Effects of Physical Activity on Cognitive Function

    OpenAIRE

    Leckie, Regina L.; Manuck, Stephen B.; Bhattacharee, Neha; Muldoon, Matthew F.; Flory, Janine M.; Erickson, Kirk I.

    2014-01-01

    Greater amounts of physical activity (PA) and omega-3 fatty acids have both been independently associated with better cognitive performance. Because of the overlapping biological effects of omega-3 fatty acids and PA, fatty acid intake may modify the effects of PA on neurocognitive function. The present study tested this hypothesis by examining whether the ratio of serum omega-6 to omega-3 fatty acid levels would moderate the association between PA and executive and memory functions in 344 pa...

  5. Conventional methods fail to measure cp(omega) of glass-forming liquids

    DEFF Research Database (Denmark)

    Christensen, Tage Emil; Olsen, Niels Boye; Dyre, Jeppe

    2007-01-01

    thermal-wave method does not measure the isobaric frequency-dependent specific heat cp(omega). This method rather measures a "longitudinal" frequency-dependent specific heat, a quantity defined and detailed here that is in between cp(omega) and cV(omega). This result means that no reliable wide......-frequency measurements of cp(omega) on liquids approaching the calorimetric glass transition exist. We briefly discuss consequences for experiment....

  6. Analytical electron microscope study of the omega phase transformation in a zirconium-niobium alloy

    Energy Technology Data Exchange (ETDEWEB)

    Zaluzec, N. J.

    1979-01-01

    The study of the as-quenched omega phase morphology shows that the domain size of Zr-15% Nb is on the order of 30 A. No alignment of omega domains along <222>..beta.. directions was observed and samples having undergone thermal cycling in thin foil form, did not develop a long-period structure of alternating ..beta.. and ..omega.. phases below the omega transformation temperature. (FS)

  7. Transmitted Laser Beam Diagnostic at the Omega Laser Facility

    Energy Technology Data Exchange (ETDEWEB)

    Niemann, C; Antonini, G; Compton, S; Glenzer, S; Hargrove, D; Moody, J; Kirkwood, R; Rekow, V; Sorce, C; Armstrong, W; Bahr, R; Keck, R; Pien, G; Seka, W; Thorp, K

    2004-04-01

    We have developed and commissioned a transmitted beam diagnostic (TBD) for the 2{omega} high intensity interaction beam at the Omega laser facility. The TBD consists of a bare-surface reflector mounted near the target, which collects and reflects 4% of the transmitted light to a detector assembly outside the vacuum chamber. The detector includes a time integrating near-field camera that measures beam spray, deflection and the absolute transmitted power. We present a detailed description of the instrument and the calibration method and include first measurements on laser heated gasbag targets to demonstrate the performance of the diagnostic.

  8. Preparation of omega-functionalized eicosane-phosphate building blocks.

    Science.gov (United States)

    Jablonkai, Istvan; Oroszlan, Peter

    2005-01-01

    New 1,20-substituted eicosanes carrying phosphate headgroups and readily derivatizable thiol, maleimido, and activated carboxylic ester moieties were prepared. The C20-backbone of these molecules was assembled by a halopolycarbon homologation from 1,8-dichlorooctane and 1,6-dibromohexane. 20-Mercapto- and 20-maleimido-icosylphosphates were synthesized via omega-bromo di-t-butyl protected icosylphosphate while 20-phosphonooxy-icosanoic acid N-hydroxysuccinimidoyl ester was prepared via omega-bromo dibenzyl protected icosylphosphate in multistep syntheses. These molecules can serve as model compounds for studying binding and structural organization on different surfaces with potential applications in the fields of biosensors.

  9. The effect of Omega3 on depression disorder

    Directory of Open Access Journals (Sweden)

    mandana saki

    2011-06-01

    Results: The findings indicated that the average grade obtained from Beck inventory in the both groups treated with Omega3 and Nortriptyline during a 3- month period was decreased remarkably . Also the patients 'performances improved during this period . Statistical Analysis showed a significant relationship among average grade in Beck inventory and performance level gained by the patients. Conclusion: Based on the research findings and the proved effects of Omega3 on the treatment of depression , it is recommended that these should be prescribed for non psychotic depression as the first stage of treatment .

  10. gamma-linolenic acid does not augment long-chain polyunsaturated fatty acid omega-3 status

    NARCIS (Netherlands)

    Brouwer, DAJ; Hettema, Y; van Doormaal, JJ; Muskiet, FAJ

    1998-01-01

    Augmentation of long chain polyunsaturated omega 3 fatty acid (LCPUFA omega 3) status can be reached by consumption of fish oil or by improvement of the conversion of a-linolenic acid (ALA) to LCPUFA omega 3. Since gamma-linolenic acid (GLA) might activate the rate-limiting Delta-6 desaturation, we

  11. Evidence for two enzymatic pathways for omega-oxidation of docosanoic acid in rat liver microsomes

    NARCIS (Netherlands)

    Sanders, Robert-Jan; Ofman, Rob; Valianpour, Fredoen; Kemp, Stephan; Wanders, Ronald J. A.

    2005-01-01

    We studied the omega-oxidation of docosanoic acid (C22:0) in rat liver microsomes. C22:0 and 22-hydroxy-docosanoic acid (omega-hydroxy-C22:0) were used as substrates, and the reaction products were analyzed by electrospray ionization mass spectrometry. In the presence of NADPH, omega-oxidation of

  12. Cecropia peltata l.: Estudios farmacognósticos y de la composición de ácidos grasos libres

    Directory of Open Access Journals (Sweden)

    Abel A Pardo Concepción

    2000-08-01

    Full Text Available Se inició el estudio de la yagruma (Cecropia peltata L. de uso medicinal en Cuba, con la descripción de los índices farmacognósticos mínimos necesarios para establecer la calidad de las hojas de la planta como droga, así como el estudio de la fracción de desengrase de donde se cristaliza una mezcla de 11 ácidos grasos metilados en forma libre, los cuales se caracterizan mediante cromatografía gaseosa acoplada a masas. El 50 % de estos ácidos son insaturados, lo cual puede favorecer el fundamento del uso de la planta popularmente con fines antiasmáticos.The study of yagruma (Cecropia peltata L. of medicinal use in Cuba was started with the description of the minimum pharmacognostic indexes necessary to establish the quality of the leaves of the plant as a drug, as well as the study of the scouring fraction from where a mix of 11 freely methylated fatty acids is crystallized. These acids are characterized by gas chromatography matched to masses. 50% of these acids are unsaturated, which may favor the popular use of the plant with antiasthmatic ends.

  13. Omega-3/Omega-6 Fatty Acids for Attention Deficit Hyperactivity Disorder: A Randomized Placebo-Controlled Trial in Children and Adolescents

    Science.gov (United States)

    Johnson, Mats; Ostlund, Sven; Fransson, Gunnar; Kadesjo, Bjorn; Gillberg, Christopher

    2009-01-01

    Objective: The aim of the study was to assess omega 3/6 fatty acids (eye q) in attention deficit hyperactivity disorder (ADHD). Method: The study included a randomized, 3-month, omega 3/6 placebo-controlled, one-way crossover trial with 75 children and adolescents (8-18 years), followed by 3 months with omega 3/6 for all. Investigator-rated ADHD…

  14. Design of the OmegaCAM Instrument Software

    Science.gov (United States)

    Baruffolo, Andrea; Bortolussi, Alessandro; De Pizzol, Luigi; Magagna, Carlo E.

    2002-12-01

    OmegaCAM is a wide field optical imager that is expected to start its operations towards the end of 2003, at the VLT Survey Telescope (VST), part of the VLT Observatory, operated in Paranal (Chile) by the European Southern Observatory (ESO). OmegaCAM will almost completely fill VST one squared degree field of view with a CCD imaging mosaic 16k x 16k pixels in size. In addition to the scientific array, four auxiliary CCDs will be used for autoguiding and image analysis. Despite its conceptual simplicity and due to the large size of the CCD mosaic, OmegaCAM posed several challenges in the design of its mechanics, electronics, cryogenics and software. In this paper we report on the design of the OmegaCAM Instrument Software (INS), which is in charge of the control and operations of the instrument. We first introduce the instrument control system characteristics and the INS software development process. We then describe the main characteristics of the INS subsystems in charge of instrument functions control, autoguiding, image analysis and operations coordination. Finally, we discuss the performances expected from the software in the acquisition and storage of the large amount of data that will come from the scientific array.

  15. Omega-6 fatty acid biomarkers and incident type 2 diabetes

    NARCIS (Netherlands)

    Wu, Jason H.Y.; Marklund, Matti; Imamura, Fumiaki; Tintle, Nathan; Ardisson Korat, Andres V.; Goede, de Janette; Zhou, Xia; Yang, Wei Sin; Oliveira Otto, de Marcia C.; Kröger, Janine; Qureshi, Waqas; Virtanen, Jyrki K.; Bassett, Julie K.; Frazier-Wood, Alexis C.; Lankinen, Maria; Murphy, Rachel A.; Rajaobelina, Kalina; Gobbo, Del Liana C.; Forouhi, Nita G.; Luben, Robert; Khaw, Kay Tee; Wareham, Nick; Kalsbeek, Anya; Veenstra, Jenna; Luo, Juhua; Hu, Frank B.; Lin, Hung Ju; Siscovick, David S.; Boeing, Heiner; Chen, Tzu An; Steffen, Brian; Steffen, Lyn M.; Hodge, Allison; Eriksdottir, Gudny; Smith, Albert V.; Gudnason, Vilmunder; Harris, Tamara B.; Brouwer, Ingeborg A.; Berr, Claudine; Helmer, Catherine; Samieri, Cecilia; Laakso, Markku; Tsai, Michael Y.; Giles, Graham G.; Nurmi, Tarja; Wagenknecht, Lynne; Schulze, Matthias B.; Lemaitre, Rozenn N.; Chien, Kuo Liong; Soedamah-Muthu, Sabita S.; Geleijnse, Johanna M.; Sun, Qi; Harris, William S.; Lind, Lars; Ärnlöv, Johan; Riserus, Ulf; Micha, Renata; Mozaffarian, Dariush

    2017-01-01

    Background: The metabolic effects of omega-6 polyunsaturated fatty acids (PUFAs) remain contentious, and little evidence is available regarding their potential role in primary prevention of type 2 diabetes. We aimed to assess the associations of linoleic acid and arachidonic acid biomarkers with

  16. Prevention of Sports Injuries by Marine Omega-3 Fatty Acids.

    Science.gov (United States)

    Bryhn, Morten

    2015-01-01

    Sport injuries are common and costly for the professional athlete, the "weekend warrior," and the community. Acute injuries are treated according to current guidelines with the aim of bringing the athlete back into the arena. These guidelines have not taken into account new scientific results of the inflammatory process following a trauma. The 4 hallmarks of inflammation, namely, pain, swelling, redness, and heat, are results of an adequate inflammatory response with the aim of bringing the affected tissue back to restitution (Latin: restitutio ad integrum). Cooling of the affected limb and anti-inflammatory drugs are widely used but may deter healing. The healing process is governed by fatty acids of the omega-3 and omega-6 series. In order to facilitate healing, these fatty acids have to be present in significant amounts in the affected tissues before the trauma occurs. This is particularly relevant for marine omega-3 fatty acids, which are often running low due to insignificant intake of seafood, common in individuals practicing sports. High-energy sports often lead to head and brain trauma. Continuous head traumata may even result in later mental defects. Saturation of brain cells with omega-3 fatty acids, in particular docosahexaenoic acid (DHA), may facilitate healing after brain trauma, thereby counteracting negative long-term results. The present understanding of a normal inflammatory process leading to restitution will be discussed along with data from recent scientific trials.

  17. Health Benefits and Omega-3-Fatty Acid Content of Selected ...

    African Journals Online (AJOL)

    The results of the study revealed that some indigenous green leafy vegetables have a high content of omega-3-fatty acids per fatty acid content. Indigenous foods were taken for their functional properties. Food items like Mormodica balsamina were identified to treat and prevent hypertension and diabetes mellitus. The food ...

  18. Oxidation of Marine Omega-3 Supplements and Human Health

    Directory of Open Access Journals (Sweden)

    Benjamin B. Albert

    2013-01-01

    Full Text Available Marine omega-3 rich oils are used by more than a third of American adults for a wide range of purported benefits including prevention of cardiovascular disease. These oils are highly prone to oxidation to lipid peroxides and other secondary oxidation products. Oxidized oils may have altered biological activity making them ineffective or harmful, though there is also evidence that some beneficial effects of marine oils could be mediated through lipid peroxides. To date, human clinical trials have not reported the oxidative status of the trial oil. This makes it impossible to understand the importance of oxidation to efficacy or harm. However, animal studies show that oxidized lipid products can cause harm. Oxidation of trial oils may be responsible for the conflicting omega-3 trial literature, including the prevention of cardiovascular disease. The oxidative state of an oil can be simply determined by the peroxide value and anisidine value assays. We recommend that all clinical trials investigating omega-3 harms or benefits report the results of these assays; this will enable better understanding of the benefits and harms of omega-3 and the clinical importance of oxidized supplements.

  19. Golden Jubilee photos: The Alpha and the OMEGA

    CERN Document Server

    2004-01-01

    In 1972, the OMEGA spectrometer was commissioned in the West Area and more than a million collisions were recorded that very first year. OMEGA was equipped with spark chambers - replaced at the end of the 1970s by electronic detectors - and a 15 000-tonne superconducting magnet. On this photo we can see the magnet's lower coil and, in the foreground, the support plate for the upper coil. No fewer than 48 experiments made use of this device, exploiting beams of various particles at various energies - from the PS at the beginning, and then from the highest energy beams of the SPS. OMEGA thus played a key role in many physics results and activities, notably the production of the J/psi particle, the study of particles carrying charm or beauty quarks, the study of «gluonia», and the CERN heavy ion programme. The OMEGA experiments ceased in 1996 when the facilities in the West Hall were shut down in preparation for the construction of the LHC.

  20. ORION-the Omega Remote Interactive On-line System

    CERN Document Server

    Russell, R D; Levratt, B; Lipps, H; Sparrman, P

    1974-01-01

    ORION is a system which permits the manipulation of files, records and characters, remote job submittal and retrieval of output files including the direct loading of remote on-line computers. The system uses the computer hardware of the OMEGA project at CERN and is designed to assist researchers in development and debugging of their programs. (10 refs).

  1. ORION - the OMEGA Remote Interactive On-line System

    CERN Document Server

    Russell, R D; Krieger, M

    1973-01-01

    ORION is a system which permits the manipulation of files, records and characters, remote job submittal and retrieval of output files including the direct loading of remote on-line computers. The system uses the computer hardware of the OMEGA project at CERN, and is designed to assist researchers in development and debugging of their programs.

  2. Semiclassical approximations in non-linear. sigma. omega. models

    Energy Technology Data Exchange (ETDEWEB)

    Centelles, M.; Vinas, X.; Barranco, M. (Dept. ECM, Univ. Barcelona (Spain)); Marcos, S. (Dept. de Fisica Moderna, Univ. de Cantabria, Santander (Spain)); Lombard, R.J. (Div. de Physique Theorique, Inst. de Physique Nucleaire, 91 - Orsay (France))

    1992-02-24

    Extended Thomas-Fermi calculations up to second order in {Dirac h} have been performed for relativistic non-linear {sigma}{omega} models and compared with the corresponding Hartree calculations. In several respects, the relativistic phenomenology quite resembles the one previously found in the non-relativistic context using Skyrme forces. (orig.).

  3. Effect of Omega-3 Fatty Acids Treatment on Insulin Resistance

    Directory of Open Access Journals (Sweden)

    Mogoş Tiberius

    2014-12-01

    Full Text Available Background and aims: Insulin resistance (IR is a common pathogenic factor of several diseases: diabetes mellitus, the metabolic syndrome, arterial hypertension, atherosclerosis, dyslipidemia, etc. There are many therapeutic factors involved in decreasing IR. Among them we mention metformin, pioglitazone, physical activity, weight loss, diet, etc. In the last decade, there are more observations of the influence of polyunsaturated fatty acids on IR. The most powerful seem to be omega-3 fatty acids. In our study, we wanted to asses if the administration of omega-3 fatty acids is involved in modifying IR. Materials and methods: We evaluated 126 diabetic patients with IR from January 2011 until July 2014. The study was open-label and non-randomized. For the determination of IR we used the HOMA-IR method. Results: For both males and females there was a regression of HOMA-IR during the 4 weeks of treatment with omega-3 and also after 2 weeks after stopping the administration of these fatty acids. The decrease of HOMA-IR was statistically significant (p<0.05. The statistic result observed in the next 2 weeks after stopping administration of omega-3 was also significant (p<0.05.

  4. A Statistical Approach to Implosion Design on the OMEGA Laser

    Science.gov (United States)

    Gopalaswamy, V.; Betti, R.

    2017-10-01

    The 1-D campaign on OMEGA is backed by a novel approach aimed at producing an iterative and data-driven process to design optimized cryogenic implosions and improve the accuracy of 1-D physics models. The process does not preclude the possibility of significant systematic errors on OMEGA, nor does it assume that the hydrodynamic codes used in implosion design have all the necessary physical models. It only assumes that there exists some relationship between simulation and experimental results and uses statistical methods to model this relationship. Comparisons of hydrodynamic simulations of less-accurate physical models with more-accurate ones indicate that as long as equation of state is relatively well modeled, this assumption holds. By incorporating data from over 40 experiments on OMEGA, this approach has been used to design four targets with a two-shock pulse design for the 1-D campaign, and led to pre-shot predictions of yields within 5% and ion temperatures within 3% of the experimental values. One of these implosions has also produced the highest neutron yield (1.1 ×1014) on an OMEGA cryogenic implosion with an areal density of 105mgmgcm cm2 . The region of design space in which the predictive capability of this model is valid remains an open question. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

  5. Differences in omega-3 and omega-6 polyunsaturated fatty acid consumption in people at ultra-high risk of psychosis, first-episode schizophrenia, and in healthy controls.

    Science.gov (United States)

    Pawełczyk, Tomasz; Trafalska, Elżbieta; Pawełczyk, Agnieszka; Kotlicka-Antczak, Magdalena

    2017-12-01

    Supplementation with omega-3 PUFA showed efficacy in reducing the risk of transition into psychosis in UHR individuals. It is uncertain whether dietary patterns can be partly responsible for n-3 deficiencies observed in susceptible participants before the diagnosis of schizophrenia. The study was designed to assess differences in omega-3 and omega-6 PUFA consumption in healthy controls (HC), UHR participants and FES patients as well as to verify the hypothesis that dietary changes in PUFA consumption are present before active psychosis develops, that is, in UHR individuals. Dietary habits during the previous year were assessed in 34 patients at UHR of psychosis, 33 patients diagnosed with FES and 33 HC participants using a validated Food-Frequency Questionnaire and the Polish Food Composition Tables. Significant differences in omega-3 and omega-6 PUFA intake were observed between study groups. UHR and FES groups reported significantly higher consumption of omega-6 PUFA in comparison with HC. FES patients also reported a higher consumption of alpha-linolenic acid (omega-3) in comparison with HC. No significant differences were seen in consumption of long-chain marine PUFA. Differences in omega-6 and omega-3 PUFA consumption exist before development of psychotic symptoms, fulfilling the criteria of schizophrenia. © 2015 Wiley Publishing Asia Pty Ltd.

  6. Measurement of the mass and lifetime of the $\\Omega_b^-$ baryon

    CERN Document Server

    Aaij, Roel; Adeva, Bernardo; Adinolfi, Marco; Ajaltouni, Ziad; Akar, Simon; Albrecht, Johannes; Alessio, Federico; Alexander, Michael; Ali, Suvayu; Alkhazov, Georgy; Alvarez Cartelle, Paula; Alves Jr, Antonio Augusto; Amato, Sandra; Amerio, Silvia; Amhis, Yasmine; An, Liupan; Anderlini, Lucio; Andreassi, Guido; Andreotti, Mirco; Andrews, Jason; Appleby, Robert; Aquines Gutierrez, Osvaldo; Archilli, Flavio; d'Argent, Philippe; Artamonov, Alexander; Artuso, Marina; Aslanides, Elie; Auriemma, Giulio; Baalouch, Marouen; Bachmann, Sebastian; Back, John; Badalov, Alexey; Baesso, Clarissa; Baker, Sophie; Baldini, Wander; Barlow, Roger; Barschel, Colin; Barsuk, Sergey; Barter, William; Batozskaya, Varvara; Battista, Vincenzo; Bay, Aurelio; Beaucourt, Leo; Beddow, John; Bedeschi, Franco; Bediaga, Ignacio; Bel, Lennaert; Bellee, Violaine; Belloli, Nicoletta; Belyaev, Ivan; Ben-Haim, Eli; Bencivenni, Giovanni; Benson, Sean; Benton, Jack; Berezhnoy, Alexander; Bernet, Roland; Bertolin, Alessandro; Betti, Federico; Bettler, Marc-Olivier; van Beuzekom, Martinus; Bifani, Simone; Billoir, Pierre; Bird, Thomas; Birnkraut, Alex; Bizzeti, Andrea; Blake, Thomas; Blanc, Frédéric; Blouw, Johan; Blusk, Steven; Bocci, Valerio; Bondar, Alexander; Bondar, Nikolay; Bonivento, Walter; Borgheresi, Alessio; Borghi, Silvia; Borisyak, Maxim; Borsato, Martino; Boubdir, Meriem; Bowcock, Themistocles; Bowen, Espen Eie; Bozzi, Concezio; Braun, Svende; Britsch, Markward; Britton, Thomas; Brodzicka, Jolanta; Buchanan, Emma; Burr, Christopher; Bursche, Albert; Buytaert, Jan; Cadeddu, Sandro; Calabrese, Roberto; Calvi, Marta; Calvo Gomez, Miriam; Campana, Pierluigi; Campora Perez, Daniel; Capriotti, Lorenzo; Carbone, Angelo; Carboni, Giovanni; Cardinale, Roberta; Cardini, Alessandro; Carniti, Paolo; Carson, Laurence; Carvalho Akiba, Kazuyoshi; Casse, Gianluigi; Cassina, Lorenzo; Castillo Garcia, Lucia; Cattaneo, Marco; Cauet, Christophe; Cavallero, Giovanni; Cenci, Riccardo; Charles, Matthew; Charpentier, Philippe; Chatzikonstantinidis, Georgios; Chefdeville, Maximilien; Chen, Shanzhen; Cheung, Shu-Faye; Chobanova, Veronika; Chrzaszcz, Marcin; Cid Vidal, Xabier; Ciezarek, Gregory; Clarke, Peter; Clemencic, Marco; Cliff, Harry; Closier, Joel; Coco, Victor; Cogan, Julien; Cogneras, Eric; Cogoni, Violetta; Cojocariu, Lucian; Collazuol, Gianmaria; Collins, Paula; Comerma-Montells, Albert; Contu, Andrea; Cook, Andrew; Coquereau, Samuel; Corti, Gloria; Corvo, Marco; Couturier, Benjamin; Cowan, Greig; Craik, Daniel Charles; Crocombe, Andrew; Cruz Torres, Melissa Maria; Cunliffe, Samuel; Currie, Robert; D'Ambrosio, Carmelo; Dall'Occo, Elena; Dalseno, Jeremy; David, Pieter; Davis, Adam; De Aguiar Francisco, Oscar; De Bruyn, Kristof; De Capua, Stefano; De Cian, Michel; De Miranda, Jussara; De Paula, Leandro; De Simone, Patrizia; Dean, Cameron Thomas; Decamp, Daniel; Deckenhoff, Mirko; Del Buono, Luigi; Déléage, Nicolas; Demmer, Moritz; Derkach, Denis; Deschamps, Olivier; Dettori, Francesco; Dey, Biplab; Di Canto, Angelo; Dijkstra, Hans; Dordei, Francesca; Dorigo, Mirco; Dosil Suárez, Alvaro; Dovbnya, Anatoliy; Dreimanis, Karlis; Dufour, Laurent; Dujany, Giulio; Dungs, Kevin; Durante, Paolo; Dzhelyadin, Rustem; Dziurda, Agnieszka; Dzyuba, Alexey; Easo, Sajan; Egede, Ulrik; Egorychev, Victor; Eidelman, Semen; Eisenhardt, Stephan; Eitschberger, Ulrich; Ekelhof, Robert; Eklund, Lars; El Rifai, Ibrahim; Elsasser, Christian; Ely, Scott; Esen, Sevda; Evans, Hannah Mary; Evans, Timothy; Falabella, Antonio; Färber, Christian; Farley, Nathanael; Farry, Stephen; Fay, Robert; Fazzini, Davide; Ferguson, Dianne; Fernandez Albor, Victor; Ferrari, Fabio; Ferreira Rodrigues, Fernando; Ferro-Luzzi, Massimiliano; Filippov, Sergey; Fiore, Marco; Fiorini, Massimiliano; Firlej, Miroslaw; Fitzpatrick, Conor; Fiutowski, Tomasz; Fleuret, Frederic; Fohl, Klaus; Fontana, Marianna; Fontanelli, Flavio; Forshaw, Dean Charles; Forty, Roger; Frank, Markus; Frei, Christoph; Frosini, Maddalena; Fu, Jinlin; Furfaro, Emiliano; Gallas Torreira, Abraham; Galli, Domenico; Gallorini, Stefano; Gambetta, Silvia; Gandelman, Miriam; Gandini, Paolo; Gao, Yuanning; García Pardiñas, Julián; Garra Tico, Jordi; Garrido, Lluis; Garsed, Philip John; Gascon, David; Gaspar, Clara; Gavardi, Laura; Gazzoni, Giulio; Gerick, David; Gersabeck, Evelina; Gersabeck, Marco; Gershon, Timothy; Ghez, Philippe; Gianì, Sebastiana; Gibson, Valerie; Girard, Olivier Göran; Giubega, Lavinia-Helena; Gligorov, V.V.; Göbel, Carla; Golubkov, Dmitry; Golutvin, Andrey; Gomes, Alvaro; Gotti, Claudio; Grabalosa Gándara, Marc; Graciani Diaz, Ricardo; Granado Cardoso, Luis Alberto; Graugés, Eugeni; Graverini, Elena; Graziani, Giacomo; Grecu, Alexandru; Griffith, Peter; Grillo, Lucia; Grünberg, Oliver; Gushchin, Evgeny; Guz, Yury; Gys, Thierry; Hadavizadeh, Thomas; Hadjivasiliou, Christos; Haefeli, Guido; Haen, Christophe; Haines, Susan; Hall, Samuel; Hamilton, Brian; Han, Xiaoxue; Hansmann-Menzemer, Stephanie; Harnew, Neville; Harnew, Samuel; Harrison, Jonathan; He, Jibo; Head, Timothy; Heister, Arno; Hennessy, Karol; Henrard, Pierre; Henry, Louis; Hernando Morata, Jose Angel; van Herwijnen, Eric; Heß, Miriam; Hicheur, Adlène; Hill, Donal; Hoballah, Mostafa; Hombach, Christoph; Hongming, Li; Hulsbergen, Wouter; Humair, Thibaud; Hushchyn, Mikhail; Hussain, Nazim; Hutchcroft, David; Idzik, Marek; Ilten, Philip; Jacobsson, Richard; Jaeger, Andreas; Jalocha, Pawel; Jans, Eddy; Jawahery, Abolhassan; John, Malcolm; Johnson, Daniel; Jones, Christopher; Joram, Christian; Jost, Beat; Jurik, Nathan; Kandybei, Sergii; Kanso, Walaa; Karacson, Matthias; Karbach, Moritz; Karodia, Sarah; Kecke, Matthieu; Kelsey, Matthew; Kenyon, Ian; Kenzie, Matthew; Ketel, Tjeerd; Khairullin, Egor; Khanji, Basem; Khurewathanakul, Chitsanu; Kirn, Thomas; Klaver, Suzanne; Klimaszewski, Konrad; Kolpin, Michael; Komarov, Ilya; Koopman, Rose; Koppenburg, Patrick; Kozeiha, Mohamad; Kravchuk, Leonid; Kreplin, Katharina; Kreps, Michal; Krokovny, Pavel; Kruse, Florian; Krzemien, Wojciech; Kucewicz, Wojciech; Kucharczyk, Marcin; Kudryavtsev, Vasily; Kuonen, Axel Kevin; Kurek, Krzysztof; Kvaratskheliya, Tengiz; Lacarrere, Daniel; Lafferty, George; Lai, Adriano; Lambert, Dean; Lanfranchi, Gaia; Langenbruch, Christoph; Langhans, Benedikt; Latham, Thomas; Lazzeroni, Cristina; Le Gac, Renaud; van Leerdam, Jeroen; Lees, Jean-Pierre; Lefèvre, Regis; Leflat, Alexander; Lefrançois, Jacques; Lemos Cid, Edgar; Leroy, Olivier; Lesiak, Tadeusz; Leverington, Blake; Li, Yiming; Likhomanenko, Tatiana; Lindner, Rolf; Linn, Christian; Lionetto, Federica; Liu, Bo; Liu, Xuesong; Loh, David; Longstaff, Iain; Lopes, Jose; Lucchesi, Donatella; Lucio Martinez, Miriam; Luo, Haofei; Lupato, Anna; Luppi, Eleonora; Lupton, Oliver; Lusardi, Nicola; Lusiani, Alberto; Lyu, Xiao-Rui; Machefert, Frederic; Maciuc, Florin; Maev, Oleg; Maguire, Kevin; Malde, Sneha; Malinin, Alexander; Manca, Giulia; Mancinelli, Giampiero; Manning, Peter Michael; Mapelli, Alessandro; Maratas, Jan; Marchand, Jean François; Marconi, Umberto; Marin Benito, Carla; Marino, Pietro; Marks, Jörg; Martellotti, Giuseppe; Martin, Morgan; Martinelli, Maurizio; Martinez Santos, Diego; Martinez Vidal, Fernando; Martins Tostes, Danielle; Massacrier, Laure Marie; Massafferri, André; Matev, Rosen; Mathad, Abhijit; Mathe, Zoltan; Matteuzzi, Clara; Mauri, Andrea; Maurin, Brice; Mazurov, Alexander; McCann, Michael; McCarthy, James; McNab, Andrew; McNulty, Ronan; Meadows, Brian; Meier, Frank; Meissner, Marco; Melnychuk, Dmytro; Merk, Marcel; Merli, Andrea; Michielin, Emanuele; Milanes, Diego Alejandro; Minard, Marie-Noelle; Mitzel, Dominik Stefan; Molina Rodriguez, Josue; Monroy, Ignacio Alberto; Monteil, Stephane; Morandin, Mauro; Morawski, Piotr; Mordà, Alessandro; Morello, Michael Joseph; Moron, Jakub; Morris, Adam Benjamin; Mountain, Raymond; Muheim, Franz; Müller, Dominik; Müller, Janine; Müller, Katharina; Müller, Vanessa; Mussini, Manuel; Muster, Bastien; Naik, Paras; Nakada, Tatsuya; Nandakumar, Raja; Nandi, Anita; Nasteva, Irina; Needham, Matthew; Neri, Nicola; Neubert, Sebastian; Neufeld, Niko; Neuner, Max; Nguyen, Anh Duc; Nguyen-Mau, Chung; Niess, Valentin; Nieswand, Simon; Niet, Ramon; Nikitin, Nikolay; Nikodem, Thomas; Novoselov, Alexey; O'Hanlon, Daniel Patrick; Oblakowska-Mucha, Agnieszka; Obraztsov, Vladimir; Ogilvy, Stephen; Okhrimenko, Oleksandr; Oldeman, Rudolf; Onderwater, Gerco; Osorio Rodrigues, Bruno; Otalora Goicochea, Juan Martin; Otto, Adam; Owen, Patrick; Oyanguren, Maria Aranzazu; Palano, Antimo; Palombo, Fernando; Palutan, Matteo; Panman, Jacob; Papanestis, Antonios; Pappagallo, Marco; Pappalardo, Luciano; Pappenheimer, Cheryl; Parker, William; Parkes, Christopher; Passaleva, Giovanni; Patel, Girish; Patel, Mitesh; Patrignani, Claudia; Pearce, Alex; Pellegrino, Antonio; Penso, Gianni; Pepe Altarelli, Monica; Perazzini, Stefano; Perret, Pascal; Pescatore, Luca; Petridis, Konstantinos; Petrolini, Alessandro; Petruzzo, Marco; Picatoste Olloqui, Eduardo; Pietrzyk, Boleslaw; Pikies, Malgorzata; Pinci, Davide; Pistone, Alessandro; Piucci, Alessio; Playfer, Stephen; Plo Casasus, Maximo; Poikela, Tuomas; Polci, Francesco; Poluektov, Anton; Polyakov, Ivan; Polycarpo, Erica; Popov, Alexander; Popov, Dmitry; Popovici, Bogdan; Potterat, Cédric; Price, Eugenia; Price, Joseph David; Prisciandaro, Jessica; Pritchard, Adrian; Prouve, Claire; Pugatch, Valery; Puig Navarro, Albert; Punzi, Giovanni; Qian, Wenbin; Quagliani, Renato; Rachwal, Bartolomiej; Rademacker, Jonas; Rama, Matteo; Ramos Pernas, Miguel; Rangel, Murilo; Raniuk, Iurii; Raven, Gerhard; Redi, Federico; Reichert, Stefanie; dos Reis, Alberto; Renaudin, Victor; Ricciardi, Stefania; Richards, Sophie; Rihl, Mariana; Rinnert, Kurt; Rives Molina, Vincente; Robbe, Patrick; Rodrigues, Ana Barbara; Rodrigues, Eduardo; Rodriguez Lopez, Jairo Alexis; Rodriguez Perez, Pablo; Rogozhnikov, Alexey; Roiser, Stefan; Romanovsky, Vladimir; Romero Vidal, Antonio; Ronayne, John William; Rotondo, Marcello; Ruf, Thomas; Ruiz Valls, Pablo; Saborido Silva, Juan Jose; Sagidova, Naylya; Saitta, Biagio; Salustino Guimaraes, Valdir; Sanchez Mayordomo, Carlos; Sanmartin Sedes, Brais; Santacesaria, Roberta; Santamarina Rios, Cibran; Santimaria, Marco; Santovetti, Emanuele; Sarti, Alessio; Satriano, Celestina; Satta, Alessia; Saunders, Daniel Martin; Savrina, Darya; Schael, Stefan; Schiller, Manuel; Schindler, Heinrich; Schlupp, Maximilian; Schmelling, Michael; Schmelzer, Timon; Schmidt, Burkhard; Schneider, Olivier; Schopper, Andreas; Schubiger, Maxime; Schune, Marie Helene; Schwemmer, Rainer; Sciascia, Barbara; Sciubba, Adalberto; Semennikov, Alexander; Sergi, Antonino; Serra, Nicola; Serrano, Justine; Sestini, Lorenzo; Seyfert, Paul; Shapkin, Mikhail; Shapoval, Illya; Shcheglov, Yury; Shears, Tara; Shekhtman, Lev; Shevchenko, Vladimir; Shires, Alexander; Siddi, Benedetto Gianluca; Silva Coutinho, Rafael; Silva de Oliveira, Luiz Gustavo; Simi, Gabriele; Sirendi, Marek; Skidmore, Nicola; Skwarnicki, Tomasz; Smith, Eluned; Smith, Iwan Thomas; Smith, Jackson; Smith, Mark; Snoek, Hella; Sokoloff, Michael; Soler, Paul; Soomro, Fatima; Souza, Daniel; Souza De Paula, Bruno; Spaan, Bernhard; Spradlin, Patrick; Sridharan, Srikanth; Stagni, Federico; Stahl, Marian; Stahl, Sascha; Stefkova, Slavomira; Steinkamp, Olaf; Stenyakin, Oleg; Stevenson, Scott; Stoica, Sabin; Stone, Sheldon; Storaci, Barbara; Stracka, Simone; Straticiuc, Mihai; Straumann, Ulrich; Sun, Liang; Sutcliffe, William; Swientek, Krzysztof; Swientek, Stefan; Syropoulos, Vasileios; Szczekowski, Marek; Szumlak, Tomasz; T'Jampens, Stephane; Tayduganov, Andrey; Tekampe, Tobias; Tellarini, Giulia; Teubert, Frederic; Thomas, Christopher; Thomas, Eric; van Tilburg, Jeroen; Tisserand, Vincent; Tobin, Mark; Tolk, Siim; Tomassetti, Luca; Tonelli, Diego; Topp-Joergensen, Stig; Tournefier, Edwige; Tourneur, Stephane; Trabelsi, Karim; Traill, Murdo; Tran, Minh Tâm; Tresch, Marco; Trisovic, Ana; Tsaregorodtsev, Andrei; Tsopelas, Panagiotis; Tuning, Niels; Ukleja, Artur; Ustyuzhanin, Andrey; Uwer, Ulrich; Vacca, Claudia; Vagnoni, Vincenzo; Valat, Sebastien; Valenti, Giovanni; Vallier, Alexis; Vazquez Gomez, Ricardo; Vazquez Regueiro, Pablo; Vázquez Sierra, Carlos; Vecchi, Stefania; van Veghel, Maarten; Velthuis, Jaap; Veltri, Michele; Veneziano, Giovanni; Vesterinen, Mika; Viaud, Benoit; Vieira, Daniel; Vieites Diaz, Maria; Vilasis-Cardona, Xavier; Volkov, Vladimir; Vollhardt, Achim; Voong, David; Vorobyev, Alexey; Vorobyev, Vitaly; Voß, Christian; de Vries, Jacco; Waldi, Roland; Wallace, Charlotte; Wallace, Ronan; Walsh, John; Wang, Jianchun; Ward, David; Watson, Nigel; Websdale, David; Weiden, Andreas; Whitehead, Mark; Wicht, Jean; Wilkinson, Guy; Wilkinson, Michael; Williams, Mark Richard James; Williams, Matthew; Williams, Mike; Williams, Timothy; Wilson, Fergus; Wimberley, Jack; Wishahi, Julian; Wislicki, Wojciech; Witek, Mariusz; Wormser, Guy; Wotton, Stephen; Wraight, Kenneth; Wright, Simon; Wyllie, Kenneth; Xie, Yuehong; Xu, Zhirui; Yang, Zhenwei; Yin, Hang; Yu, Jiesheng; Yuan, Xuhao; Yushchenko, Oleg; Zangoli, Maria; Zavertyaev, Mikhail; Zhang, Liming; Zhang, Yanxi; Zhelezov, Alexey; Zheng, Yangheng; Zhokhov, Anatoly; Zhong, Liang; Zhukov, Valery; Zucchelli, Stefano

    2016-05-19

    A proton-proton collision data sample, corresponding to an integrated luminosity of 3 fb$^{-1}$ collected by LHCb at $\\sqrt{s}=7$ and 8 TeV, is used to reconstruct $63\\pm9$ $\\Omega_b^-\\to\\Omega_c^0\\pi^-$, $\\Omega_c^0\\to pK^-K^-\\pi^+$ decays. Using the $\\Xi_b^-\\to\\Xi_c^0\\pi^-$, $\\Xi_c^0\\to pK^-K^-\\pi^+$ decay mode for calibration, the lifetime ratio and absolute lifetime of the $\\Omega_b^-$ baryon are measured to be \\begin{align*} \\frac{\\tau_{\\Omega_b^-}}{\\tau_{\\Xi_b^-}} &= 1.11\\pm0.16\\pm0.03, \\\\ \\tau_{\\Omega_b^-} &= 1.78\\pm0.26\\pm0.04\\pm0.05~{\\rm ps}, \\end{align*} where the uncertainties are statistical, systematic and from the calibration mode (for $\\tau_{\\Omega_b^-}$ only). A measurement is also made of the mass difference, $m_{\\Omega_b^-}-m_{\\Xi_b^-}$, and the corresponding $\\Omega_b^-$ mass, which yields \\begin{align*} m_{\\Omega_b^-}-m_{\\Xi_b^-} &= 247.4\\pm3.2\\pm0.5~{\\rm MeV}/c^2, \\\\ m_{\\Omega_b^-} &= 6045.1\\pm3.2\\pm 0.5\\pm0.6~{\\rm MeV}/c^2. \\end{align*} These results are consistent with p...

  7. Laser-driven magnetized liner inertial fusion on OMEGA

    Science.gov (United States)

    Barnak, D. H.; Davies, J. R.; Betti, R.; Bonino, M. J.; Campbell, E. M.; Glebov, V. Yu.; Harding, D. R.; Knauer, J. P.; Regan, S. P.; Sefkow, A. B.; Harvey-Thompson, A. J.; Peterson, K. J.; Sinars, D. B.; Slutz, S. A.; Weis, M. R.; Chang, P.-Y.

    2017-05-01

    Magneto-inertial fusion (MIF) combines the compression of fusion fuel, a hallmark of inertial confinement fusion (ICF), with strongly magnetized plasmas that suppress electron heat losses, a hallmark of magnetic fusion. It can reduce the traditional velocity, pressure, and convergence ratio requirements of ICF. The magnetized liner inertial fusion (MagLIF) concept being studied at the Z Pulsed-Power Facility is a key target concept in the U.S. ICF Program. Laser-driven MagLIF is being developed on OMEGA to test the scaling of MagLIF over a range of absorbed energy of the order of 1 kJ on OMEGA to 500 kJ on Z. It is also valuable as a platform for studying the key physics of MIF. An energy-scaled point design has been developed for OMEGA that is roughly 10 × smaller in linear dimensions than Z MagLIF targets. A 0.6-mm-outer-diameter plastic cylinder filled with 2.4 mg/cm3 of D2 is placed in a ˜10-T axial magnetic field, generated by a Magneto-inertial fusion electrical discharge system, the cylinder is compressed by 40 OMEGA beams, and the gas fill is preheated by a single OMEGA beam propagating along the axis. Preheating to >100 eV and axially uniform compression over 0.7 mm have been demonstrated, separately, in a series of preparatory experiments that meet our initial expectations. The preliminary results from the first integrated experiments combining magnetization, compression, and preheat demonstrating a roughly 2 x increase in the neutron yield will be reported here for the first time.

  8. Omega-3 Fatty Acid and Nutrient Deficits in Adverse Neurodevelopment and Childhood Behaviors

    Science.gov (United States)

    Hibbeln, Joseph. R.; Gow, Rachel V.

    2014-01-01

    Synopsis Nutritional insufficiencies of omega-3 highly unsaturated fatty acids (HUFAs) may have adverse effects on brain development and neurodevelopmental outcomes. A recent meta-analysis of ten randomized controlled trials of omega-3 HUFAs reported a small to modest effect size for the efficacy of omega-3 for treating symptoms of ADHD in youth. Several controlled trials of omega-3 HUFAs combined with micronutrients (vitamins, minerals) show sizeable reductions in aggressive, antisocial, and violent behavior in youth and in young adult prisoners. Meta-analyses report efficacy for depressive symptoms in adults, and preliminary findings suggest anti-suicidal properties in adults, but studies in youth are insufficient to draw any conclusions regarding mood. Dietary adjustments to increase omega-3 and reduce omega-6 HUFA consumption are sensible recommendations for youth and adults based on general health considerations, while the evidence base for omega-3 HUFAs as potential psychiatric treatments develops. PMID:24975625

  9. Insight into the contribution of isoprostanoids to the health effects of omega 3 PUFAs.

    Science.gov (United States)

    Joumard-Cubizolles, Laurie; Lee, Jetty Chung-Yung; Vigor, Claire; Leung, Ho Hang; Bertrand-Michel, Justine; Galano, Jean-Marie; Mazur, André; Durand, Thierry; Gladine, Cecile

    2017-11-01

    Omega 3 polyunsaturated fatty acids have been reported to confer beneficial health effects notably in the field of cardiovascular and inflammatory diseases. The current knowledge suggests a significant portion of the effects of omega 3 polyunsaturated fatty acids are mediated by their oxygenated metabolites. This review attempts to cover the current literature about the contribution of specific omega 3 oxygenated metabolites, namely omega 3 isoprostanoids, which are produced through free-radical mediated oxidation. A special emphasis has been given to the most biologically relevant omega 3 polyunsaturated fatty acids namely the α-linolenic, eicosapentaenoic and docosahexaenoic acids. The review includes a comprehensive description of the biosynthetic pathways, a summary of studies related to the biological significance of omega 3 isoprostanoids as well as a critical description of analytical development in the field of omega 3 isoprostanoids profiling in biological samples. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Vitamin E supplementation modulates the biological effects of omega-3 fatty acids in naturally aged rats.

    Science.gov (United States)

    Narayanankutty, Arunaksharan; Kottekkat, Anagha; Mathew, Shaji E; Illam, Soorya P; Suseela, Indu M; Raghavamenon, Achuthan C

    2017-03-01

    Omega-3 fatty acids are well-known class of nutraceuticals with established health benefits. Recently, the oxidation products of these fatty acids are gaining attention, as they are likely to disturb body redox balance. Therefore, the efficacy of omega-3 fats under conditions of diminished antioxidant status, such as aging, is always a concern. Present study assessed the effects of omega-3 fats (DHA and EPA) together with or without vitamin-E in naturally aged rats. It was found that in omega-3 fats alone consumed rats the lipid profile was improved, while in omega-3 fat with vitamin-E-consumed group (OMVE), the hepato protective and antioxidant properties were pronounced, especially the redox status of brain tissue. It is possible that vitamin-E might have reduced the peroxidation of omega-3 fats, thereby allowing their synergistic effects. Hence, the use of vitamin-E along with omega-3 fat may be beneficial under aged conditions.

  11. Reduction of omega-3 oil oxidation in stable emulsion of caseinate-omega-3 oil-oat beta-glucan

    Science.gov (United States)

    Lipid oxidation, particularly oxidation of unsaturated fatty acids such as omega-3 fatty acids, has posed a serious challenge to the food industry trying to incorporate heart-healthy oil products into their lines of healthful foods and beverages. In this study, heart healthy plant and marine based o...

  12. Inclusive Production of the $\\omega$ and $\\eta$ Mesons in Z Decays, and the Muonic Branching Ratio of the $\\omega$

    CERN Document Server

    Heister, A.; Barate, R.; De Bonis, I.; Decamp, D.; Goy, C.; Lees, J.P.; Merle, E.; Minard, M.N.; Pietrzyk, B.; Boix, G.; Bravo, S.; Casado, M.P.; Chmeissani, M.; Crespo, J.M.; Fernandez, E.; Fernandez-Bosman, M.; Garrido, L.; Grauges, E.; Martinez, M.; Merino, G.; Miquel, R.; Mir, L.M.; Pacheco, A.; Ruiz, H.; Colaleo, A.; Creanza, D.; de Palma, M.; Iaselli, G.; Maggi, G.; Maggi, M.; Nuzzo, S.; Ranieri, A.; Raso, G.; Ruggieri, F.; Selvaggi, G.; Silvestris, L.; Tempesta, P.; Tricomi, A.; Zito, G.; Huang, X.; Lin, J.; Ouyang, Q.; Wang, T.; Xie, Y.; Xu, R.; Xue, S.; Zhang, J.; Zhang, L.; Zhao, W.; Abbaneo, D.; Azzurri, P.; Buchmuller, O.; Cattaneo, M.; Cerutti, F.; Clerbaux, B.; Drevermann, H.; Forty, R.W.; Frank, M.; Gianotti, F.; Greening, T.C.; Hansen, J.B.; Harvey, J.; Hutchcroft, D.E.; Janot, P.; Jost, B.; Kado, M.; Mato, P.; Moutoussi, A.; Ranjard, F.; Rolandi, Gigi; Schlatter, D.; Schneider, O.; Sguazzoni, G.; Tejessy, W.; Teubert, F.; Valassi, A.; Videau, I.; Ward, J.; Badaud, F.; Falvard, A.; Gay, P.; Henrard, P.; Jousset, J.; Michel, B.; Monteil, S.; Montret, J-C.; Pallin, D.; Perret, P.; Hansen, J.D.; Hansen, J.R.; Hansen, P.H.; Nilsson, B.S.; Waananen, A.; Kyriakis, A.; Markou, C.; Simopoulou, E.; Vayaki, A.; Zachariadou, K.; Blondel, A.; Bonneaud, G.; Brient, J.-C.; Rouge, A.; Rumpf, M.; Swynghedauw, M.; Verderi, M.; Videau, H.; Ciulli, V.; Focardi, E.; Parrini, G.; Antonelli, A.; Antonelli, M.; Bencivenni, G.; Bologna, G.; Bossi, F.; Campana, P.; Capon, G.; Chiarella, V.; Laurelli, P.; Mannocchi, G.; Murtas, F.; Murtas, G.P.; Passalacqua, L.; Pepe-Altarelli, M.; Spagnolo, P.; Halley, A.; Lynch, J.G.; Negus, P.; O'Shea, V.; Raine, C.; Thompson, A.S.; Wasserbaech, S.; Cavanaugh, R.; Dhamotharan, S.; Geweniger, C.; Hanke, P.; Hansper, G.; Hepp, V.; Kluge, E.E.; Putzer, A.; Sommer, J.; Tittel, K.; Werner, S.; Wunsch, M.; Beuselinck, R.; Binnie, D.M.; Cameron, W.; Dornan, P.J.; Girone, M.; Marinelli, N.; Sedgbeer, J.K.; Thompson, J.C.; Ghete, V.M.; Girtler, P.; Kneringer, E.; Kuhn, D.; Rudolph, G.; Bouhova-Thacker, E.; Bowdery, C.K.; Finch, A.J.; Foster, F.; Hughes, G.; Jones, R.W.L.; Pearson, M.R.; Robertson, N.A.; Jakobs, K.; Kleinknecht, K.; Quast, G.; Renk, B.; Sander, H.G.; Wachsmuth, H.; Zeitnitz, C.; Bonissent, A.; Carr, J.; Coyle, P.; Leroy, O.; Payre, P.; Rousseau, D.; Talby, M.; Ragusa, F.; David, A.; Dietl, H.; Ganis, G.; Huttmann, K.; Lutjens, G.; Mannert, C.; Manner, W.; Moser, H.G.; Settles, R.; Stenzel, H.; Wiedenmann, W.; Wolf, G.; Boucrot, J.; Callot, O.; Davier, M.; Duflot, L.; Grivaz, J.F.; Heusse, P.; Jacholkowska, A.; Lefrancois, J.; Veillet, J.J.; Yuan, C.; Bagliesi, Giuseppe; Boccali, T.; Foa, L.; Giammanco, A.; Giassi, A.; Ligabue, F.; Messineo, A.; Palla, F.; Sanguinetti, G.; Sciaba, A.; Tenchini, R.; Venturi, A.; Verdini, P.G.; Blair, G.A.; Cowan, G.; Green, M.G.; Medcalf, T.; Misiejuk, A.; Strong, J.A.; Teixeira-Dias, P.; von Wimmersperg-Toeller, J.H.; Clifft, R.W.; Edgecock, T.R.; Norton, P.R.; Tomalin, I.R.; Bloch-Devaux, Brigitte; Colas, P.; Emery, S.; Kozanecki, W.; Lancon, E.; Lemaire, M.C.; Locci, E.; Perez, P.; Rander, J.; Renardy, J.F.; Roussarie, A.; Schuller, J.P.; Schwindling, J.; Trabelsi, A.; Vallage, B.; Konstantinidis, N.; Litke, A.M.; Taylor, G.; Beddall, A.; Booth, C.N.; Cartwright, S.; Combley, F.; Lehto, M.; Thompson, L.F.; Affholderbach, K.; Boehrer, Armin; Brandt, S.; Grupen, C.; Ngac, A.; Prange, G.; Sieler, U.; Giannini, G.; Rothberg, J.; Armstrong, S.R.; Berkelman, Karl; Cranmer, K.; Ferguson, D.P.S.; Gao, Y.; Gonzalez, S.; Hayes, O.J.; Hu, H.; Jin, S.; Kile, J.; McNamara, P.A., III; Nielsen, J.; Pan, Y.B.; von Wimmersperg-Toeller, J.H.; Wiedenmann, W.; Wu, J.; Wu, Sau Lan; Wu, X.; Zobernig, G.

    2002-01-01

    The inclusive production of the omega(782) vector meson in hadronic Z decays is measured and compared to model predictions. The analysis is based on 4 million hadronic Z decays recorded by the ALEPH detector between 1991 and 1995. The production rate for x_p = p_meson/p_beam > 0.05 is measured in the omega -> pi^+ pi^- pi^0 decay mode and found to be 0.585 +- 0.019_stat +- 0.033_sys per event. Inclusive eta meson production is also measured in the same decay channel for x_p > 0.10, obtaining 0.355 +- 0.011_stat +- 0.024_sys per event. The branching ratio for omega -> mu^+ mu^- is investigated. A total of 18.1 +- 5.9 events are observed, from which the muonic branching ratio is measured for the first time to be BR(omega -> mu^+ mu^-) = (9.0 +- 2.9_stat +- 1.1_sys)*10^-5.

  13. Measurements of $\\psi(2S)$ decays into $\\phi \\pi^0$, $\\phi \\eta$, $\\phi \\eta^{'}$, $\\omega \\eta$, and $\\omega \\eta^{'}$

    CERN Document Server

    Ablikim, M; Ban, Y; Bian, J G; Cai, X; Chang, J F; Chen, H F; Chen, H S; Chen, H X; Chen, J; Chen, J C; Chen, M L; Chen, Y B; Chi, S P; Chu, Y P; Cui, X Z; Dai, H L; Dai, Y S; Deng, Z Y; Dong, L Y; Du, S X; Du, Z Z; Fang, J; Fang, S S; Fu, C D; Fu, H Y; Fu, L P; Gao, C S; Gao, M L; Gao, Y N; Gong, M Y; Gong, W X; Gu, S D; Guo, Y N; Guo, Y Q; Guo, Z J; Han, S W; Harris, F A; He, J; He, K L; He, M; He, X; Heng, Y K; Hu, H M; Hu, T; Huang, G S; Huang, L; Huang, X P; Ji, X B; Jia, Q Y; Jiang, C H; Jiang, X S; Jin, D P; Jin, S; Jin, Y; Lai, Y F; Li, F; Li, G; Li, H H; Li, J; Li, J C; Li, Q J; Li, R B; Li, R Y; Li, S M; Li, W; Li, W G; Li, X L; Li, X Q; Li, X S; Liang, Y F; Liao, H B; Liu, C X; Liu, F; Liu, H M; Liu, J B; Liu, J P; Liu, R G; Liu, Y; Liu, Z A; Liu, Z X; Lu, G R; Lu, F; Lu, J G; Luo, C L; Luo, X L; Ma, F C; Ma, J M; Ma, L L; Ma, X Y; Mao, Z P; Meng, X C; Mo, X H; Nie, J; Nie, Z D; Olsen, S L; Peng, H P; Qi, N D; Qian, C D; Qin, H; Qiu, J F; Ren, Z Y; Rong, G; Shan, L Y; Shang, L; Shen, D L; Shen, X Y; Sheng, H Y; Shi, F; Shi, X; Song, L W; Sun, H S; Sun, S S; Sun, Y Z; Sun, Z J; Tang, X; Tao, N; Tian, Y R; Tong, G L; Varner, G S; Wang, D Y; Wang, J Z; Wang, L; Wang, L S; Wang, M; Wang, P; Wang, P L; Wang, S Z; Wang, W F; Wang, Y F; Zhe Wang; Wang, Z; Wang, Z Y; Wei, C L; Wu, N; Wu, Y M; Xia, X M; Xie, X X; Xin, B; Xu, G F; Xu, H; Xu, Y; Xue, S T; Yan, M L; Yan, W B; Yang, F; Yang, H X; Yang, J; Yang, S D; Yang, Y X; Yi, L H; Yi, Z Y; Ye, M; Ye, M H; Ye, Y X; Yu, C S; Yu, G W; Yuan, C Z; Yuan, J M; Yuan, Y; Yue, Q; Zang, S L; Zeng, Y; Zhang, B X; Zhang Bing Yun; Zhang, C C; Zhang, D H; Zhang, H Y; Zhang, J; Zhang, J M; Zhang, J Y; Zhang, J W; Zhang, L S; Zhang, Q J; Zhang, S Q; Zhang Xiao Min; Zhang, X Y; Zhang, Y; Zhang, Y J; Zhang, Y Y; Zhang, Z P; Zhang, Z Q; Zhao, D X; Zhao, J B; Zhao, J W; Zhao, P P; Zhao, W R; Zhao, X J; Zhao, Y B; Zhao, Z G; Zheng, H Q; Zheng, J P; Zheng, L S; Zheng, Z P; Zhong, X C; Zhou, B Q; Zhou, G M; Zhou, L; Zhou, N F; Zhu, K J; Zhu, Q M; Zhu, Y; Zhu, Y C; Zhu, Y S; Zhu, Z A; Zhuang, B A; Zou, B S

    2004-01-01

    Decays of the $\\psi(2S)$ into Vector plus Pseudoscalar meson final states have been studied with 14 million $\\psi(2S)$ events collected with the BESII detector. Branching fractions of $\\psi(2S) \\rar\\phi\\eta$, $\\phi\\etap$, and $\\omega\\etap$, and upper limits of $\\psi(2S) \\rar \\phi\\piz$ and $\\omega\\eta$ are obtained: $B(\\psi(2S) \\rar\\phi\\eta) = 3.5 \\pm 1.0 \\pm 0.6) \\times 10^{-5}$, $B(\\psi(2S) \\rar\\phi\\etap) = (3.3 \\pm 1.3 \\pm 0.7)\\times 10^{-5}$, and $B(\\psi(2S) \\rar\\omega\\etap) = (3.1 \\pm 2.4 \\pm 0.7) \\times 10^{-5}$; and $B(\\psi(2S) \\rar\\phi\\piz) < 0.3 \\times 10^{-5}$, and $B(\\psi(2S) \\rar\\omega\\eta) < 1.1 \\times 10^{-5}$ at the 90 % C.L.. These results are used to test the pQCD ``12% rule''.

  14. Omega-3 fatty acids for the treatment of dementia.

    Science.gov (United States)

    Burckhardt, Marion; Herke, Max; Wustmann, Tobias; Watzke, Stefan; Langer, Gero; Fink, Astrid

    2016-04-11

    Omega-3 polyunsaturated fatty acids (omega-3 PUFAs) from fish and plant sources are commonly considered as a promising non-medical alternative to improve brain functions and slow down the progression of dementia. This assumption is mostly based on findings of preclinical studies and epidemiological research. Resulting explanatory models aim at the role omega-3 PUFAs play in the development and integrity of the brain's neurons, their protective antioxidative effect on cell membranes and potential neurochemical mechanisms directly related to Alzheimer-specific pathology. Epidemiological research also found evidence of malnutrition in people with dementia. Considering this and the fact that omega-3 PUFA cannot be synthesised by humans, omega-3 PUFAs might be a promising treatment option for dementia. To assess the efficacy and safety of omega-3 polyunsaturated fatty acid (PUFA) supplementation for the treatment of people with dementia. We searched the Specialized Register of the Cochrane Dementia and Cognitive Improvement Group (ALOIS), MEDLINE, EMBASE, PsycINFO, CINAHL, ClinicalTrials.gov and the World Health Organization (WHO) portal/ICTRP on 10 December 2015. We contacted manufacturers of omega-3 supplements and scanned reference lists of landmark papers and included articles. We included randomised controlled trials (RCTs) in which omega-3 PUFA in the form of supplements or enriched diets were administered to people with Alzheimer's disease (AD), vascular dementia (VaD), dementia with Lewy bodies (DLB), Parkinson's disease dementia (PDD) or frontotemporal dementia (FTD). The primary outcome measures of interest were changes in global and specific cognitive functions, functional performance, dementia severity and adverse effects. Two review authors independently selected studies, extracted data and assessed the quality of trials according to the Cochrane Handbook for Systematic Reviews of Interventions. We rated the quality of the evidence using the GRADE approach

  15. Perfil de ácidos grasos de la grasa de tres variedades de pimientos (Arnoia, Fresno de la Vega y los Valles-Benavente. Influencia del grado de maduración

    Directory of Open Access Journals (Sweden)

    Franco, I.

    2006-12-01

    Full Text Available Total fatty acids content was studied in three varieties of peppers (Arnoia, Fresno de la Vega and Los Valles-Benavente in different commercial stages of ripening: green and red in the Arnoia variety and, green, breaker and red in the Fresno de la Vega and Los Valles-Benavente varieties. With ripening, an increase was observed in the lipid content in the peppers of all three varieties; the values showed are inside the range described in the literature for other varieties. At the end of maturation (red peppers, fat content allows for differentiating the three varieties under study. The fatty acid profiles were similar in the three varieties of peppers and in the three stages of ripening: the most abundant fatty acid was linoleic (C18:2 followed by linolenic  (C18:3 and palmitic (C16; these fatty acids represent more than 80% of the total fatty acids and do not show important variations during ripening in the three varieties of peppers. Minor changes in the major and minor fatty acids during ripening were observed in the Los Valles-Benavente variety. Using discriminant analysis 100% of the green, breaker and red peppers were correctly classified and differentiated from their content (% in individual fatty acids: C16, C16:1, C17, C18, C18:1Z,T, C18:2 y C18:3.Se estudió el contenido en ácidos grasos de la fracción lipídica de tres variedades de pimientos (Arnoia, Fresno de la Vega y los Valles-Benavente, en distintos estadios de maduración comercial, verde y rojo en la variedad “Arnoia” y, verde, entreverado y rojo en las variedades “Fresno de la Vega” y los “Valles-Benavente”. Con la maduración, en los pimientos de las tres variedades, se observó un aumento en el contenido lipídico; los valores encontrados están dentro del rango descrito en la bibliografía para otras variedades. Al final de la maduración (pimientos rojos el contenido en grasa permite diferenciar significativamente las tres variedades en estudio. El perfil de

  16. Contenidos de isómeros trans de los ácidos grasos en productos cárnicos. (III Tejido adiposo y grasa intramuscular de vacuno

    Directory of Open Access Journals (Sweden)

    Lluch, M. C.

    1993-06-01

    Full Text Available We give the results obtained for the determination of trans fatty acids in subcutaneous and intramuscular fats from different veal carcasses, using gas chromatography. FA composition differs clearly between both tissues, showing mean values of 58.7% SFA, 39.1% MUFA and 2.7% PUFA in the adipose tissue, and of 44.7% SFA, 46.1% MUFA and 9.4% PUFA in the muscle. Trans fatty acid values obtained in muscle and adipose tissue show statistically significant differences (mean values of 7% total trans fatty acids in intramuscular fat and 10.5% in adipose tissue fat. Besides, we observed a clearly different distribution for C 16: 1t, that didn't show these differences, while C 18: 1t showed a similar distribution than total trans fatty acids. Related to the factors that could determine the trans fatty acid contents in veal carcasses, we found that the race showed more differences between groups than the origin of the animal and their commercial category. On the other hand, correlations we found between trans fatty acids and the total of saturated, mono and polyunsaturated fatty acids showed an opposite sign according to the type of tissue (muscular or adipose. Thus, an increase in the trans fatty acid content was associated with a parallel increase of saturated and decrease in polyunsaturated fatty acid contents in the intramuscular fat. On the contrary, an increase of trans fatty acid content in adipose fat was correlated to a decrease of saturated and an increase of mono and polyunsaturated fatty acid contents.

    Se presentan los resultados obtenidos para la determinación de ácidos grasos en una serie de muestras de tejidos subcutáneo y muscular, procedentes de canales de vacuno, por aplicación de la cromatografía en fase gaseosa, para los que se obtuvieron unos valores medios de 58.7% de ácidos saturados, 39.1 % de monoinsaturados y 2.7% de polinsaturados, en el tejido adiposo, y de 44.7% de saturados, 46.1% de monoinsaturados y 9.4% de

  17. Effect of n-3 polyunsaturated fatty acids on the lipidic profile of healthy Mexican volunteers Efecto de los ácidos grasos polinsaturados n-3 en el perfil lipídico de mexicanos voluntarios

    Directory of Open Access Journals (Sweden)

    OCTAVIO CARVAJAL

    1997-05-01

    Full Text Available Objective. The effect of n-3 polyunsaturated fatty acids on the serum lipid profile in a Mexican population was evaluated. Material and methods. Three g of salmon oil was the daily intake during four weeks. Total cholesterol, triglycerides, low density lipoproteins, high density lipoproteins and erythrocyte fatty acid composition were analyzed. Results. The hypertriglyceridemic group showed a statistically significant (pObjetivo. Estudiar el efecto de los ácidos grasos polinsaturados n-3 en el perfil lipídico sérico de una población mexicana. Material y métodos. La ingesta diaria del suplemento de aceite de salmón fue de 3 gramos durante cuatro semanas. Se evaluaron los niveles de colesterol total, triglicéridos, lipoproteínas de baja densidad, lipoproteínas de alta densidad y la composición en ácidos grasos de los eritrocitos. Resultados. Muestran una reducción significativa (p< 0.05 en los niveles de triglicéridos y un aumento significativo (p< 0.01 en los niveles de lipoproteínas de alta densidad en los sujetos con hipertrigliceridemia. El grupo con hipercolesterolemia presentó reducción en los niveles de colesterol total y triglicéridos y aumento significativo en los niveles de lipoproteínas de alta densidad (p< 0.01. Conclusiones. El efecto hipolipidemiante de los ácidos grasos polinsaturados n-3 se puso de manifiesto en voluntarios mexicanos bajo las condiciones aquí evaluadas.

  18. Factores que influyen en el contenido de escualeno, fitoesteroles totales y esterificados en el subproducto ácidos grasos destilados de soya para su potencial aprovechamiento

    Directory of Open Access Journals (Sweden)

    José Rodríguez Rodríguez

    2015-01-01

    Full Text Available Una necesidad actual de la industria de extracción y refinación de aceite vegetal es la reducción y/o explotación de sus subproductos. Uno de estos, conocido como Ácidos Grasos Destilados de Aceite de Soya (AGDAS, resulta potencialmente valioso para las industrias alimentaria, farmacéutica y cosmética por la presencia de compuestos con actividad biológica favorable, como los fitoesteroles y el escualeno, los primeros como agentes hipocolesterolemiantes y el escualeno como emoliente y humectante. En este trabajo, mediante cromatografía de gases se determinó el contenido de escualeno y fitoesteroles libres y esterificados para evaluar la viabilidad de aprovechamiento de AGDAS como fuente de dichos compuestos y establecer si la procedencia del grano de soya (americano o nacional, la condición de cultivo (Sequía o Normal, años 2011 y 2012 respectivamente y el grado de calidad del aceite (Genérico o Premium son factores determinantes en el contenido de dichos compuestos en el subproducto. En conclusión AGDAS representa una fuente viable de fitoesteroles totales con 14.92% p/p, no así de escualeno con 1.75% p/p. La concentración de escualeno está influenciada por la procedencia del grano y la condición de cultivo, mientras que la de fitoesteroles esterificados por el grado de calidad y condición de cultivo. Ninguno de los factores influyó en el contenido de fitoesteroles totales. Esto permite establecer que la composición del subproducto AGDAS no es constante y se justifican protocolos como el de este estudio para su caracterización con fines de aprovechamiento.

  19. Estudio del contenido graso, del índice de yodo y del índice y grado de acidez en los turrones de Alicante y Jijona

    Directory of Open Access Journals (Sweden)

    Blázquez-Aballan, G.

    1999-04-01

    Full Text Available In this paper, a study of the fat content, and the index and degree of acidity and iodine index has been carried out in twenty four samples belonging to Alicante nougat and Jijona nougat in the Supreme and Extra qualities, which are regulated by the Spanish Regulations for Nougat and Marzipan (Reglamentación Técnico- Sanitaria para Turrones y Mazapanes. Results indicate that these nougats present high and very similar fat contents in both. The iodine indexes are higher and more disperse in the Supreme and Extra qualities of Jijona nougat. The values of acidity index, obtained indicate the good quality of the fat used in these two types of nougat.

    En el presente trabajo se ha realizado un estudio del contenido graso y de los índices de yodo e índice y grado de acidez en un total de veinticuatro muestras de turrón de Alicante y Jijona de las calidades Suprema y Extra tipificadas en la Reglamentación Técnico-Sanitaria para Turrones y Mazapanes. Se ha comprobado que los dos turrones presentan contenidos de grasa elevados y muy similares en ambos. Los índices de yodo se muestran altos y más dispares en las dos calidades del turrón de Jijona, Suprema y Extra. Los valores del índice de acidez que se han obtenido han sido bajos, lo que indica la buena calidad de la grasa de estos dos tipos de turrón.

  20. Instituto de productos lácteos y derivados grasos del P.J.C. Arganda – España

    Directory of Open Access Journals (Sweden)

    Ruiz Duerto, A.

    1973-09-01

    Full Text Available This article describes. a The CLUB-DINING-ROOM, made up of: premises for different uses, kitchen, air conditioning installation, semi-basement, stores, covered porch and covered tennis court, which can be reached from outside. Metal structure, ceramic forging and enclosures of silicocalcareous brick. b The LABORATORY BUILDING for the Institute of Dairy Products and By-Products comprises: semibasements, for plant, workshop, changing rooms, stores and other services; first floor: for direction, management, hali, board room, library and laboratory; two floors of laboratories. The structure is metal in girders and pillars, forming a three-dimensional main network —vertically and horizontally— allowing thé passage of any duct. The upright projections which undergo solar action are protected by vertical and horizontal sunbreakers which give the building a most unusual appearance.Se describen en este artículo: a El CLUB-COMEDOR, compuesto de: local para distintos usos, cocina, instalación de acondicionami¿nto de aire, semisótano, almacén, porche cubierto y campo de tenis en la cubierta, con acceso exterior. Estructura metálica, forjados cerámicos y cerramientos de ladrillo silicocalcáreo. b El EDIFICIO DE LABORATORIOS para el Instituto de Productos Lácteos y Derivados Grasos, consta de semisótano: para instalaciones, taller, vestuarios, almacén y otros servicios; planta primera: de dirección, administración, aula, juntas, biblioteca y laboratorio; dos plantas de laboratorios. La estructura es metálica en vigas y pilares, constituyendo una red principal tridimensional —en vei-tical y en horizontal— que permite el paso de cualquier conducto. Los alzados que sufren la acción solar están protegidos por córtaseles verticales y horizontales que prestan una fisonomía singular al edificio.

  1. Orejas valgas: estabilización mediante colgajo dermo-graso-pericóndrico retroauricular Prominent ears: stabilization with a retroauricular dermal-fat-perichondrium flap

    Directory of Open Access Journals (Sweden)

    J. Amorrortu

    2013-03-01

    Full Text Available El tratamiento quirúrgico para la corrección de las orejas prominentes o valgas se basa en crear una distancia de entre 17-21 mm entre el hélix y la mastoides, así como recrear unos pliegues auriculares anteriores bien definidos. Desde finales de 1800 hasta la actualidad se han descrito muchas técnicas para corregir las orejas despegadas, prominentes o valgas, cada una de ellas con sus propias características. En el presente trabajo describimos una técnica para estabilizar el resultado quirúrgico cuando se corrige esta entidad y evitar su recidiva. Se trata de un procedimiento de fijación mastoidea de la oreja mediante un colgajo dermo-graso-pericóndrico de sencillo diseño, útil, seguro y fácilmente reproducible. Hemos empleado esta técnica durante más de 15 años y creemos que ha resistido la prueba del tiempo.The treatment for the correction of prominent or valgus ears, is to create a normal distance (17-21 mm between the mastoid and the helix and a normal appearance of the anterior auricular folds. From late 1800 to the present, many surgical techniques for correcting prominent or valgus ears have been described, each one with its own characteristics. We describe a technique to stabilize the result and prevent recurrence. This technique stabilizes the correction of the ear fixing it to the mastoid fascia using a dermalfat-perichondrium flap of simple design, useful, safe and easily reproducible. We have used it over 15 years, and that makes us believe that has stood the test of time.

  2. Efecto del riego y la poda en el contenido de componentes menores y ácidos grasos del aceite de oliva virgen varietal Farga

    Directory of Open Access Journals (Sweden)

    Monteleone, J. I.

    2013-09-01

    componentes vinculados a la estabilidad oxidativa de los aceites de oliva vírgenes (polifenoles, clorofilas y carotenoides, variedad Farga. Se aplicaron cuatro tratamientos: T100%SP (riego equivalente al 100% de la demanda evapotranspiratoria (Etc del cultivo durante todo el ciclo y sin poda invernal; T50%SP (riego que equivalente al 50% de la Etc desde endurecimiento de carozo hasta cosecha y sin poda; T100%CP (riego 100% y con poda; T50%CP (riego deficitario y con poda. Se monitoreó el estado hídrico de las plantas a través del potencial hídrico del tallo a mediodía (PHT, el contenido de humedad del suelo y la radiación fotosintéticamente activa incidente en el interior de la copa de los olivos. El muestreo de aceitunas se extendió desde pre-envero hasta maduración completa. El aceite se extrajo en laboratorio por molienda de las aceitunas con molino de tornillo, termo-amasado, separación de fases sólida y líquida con una prensa manual y decantación para separar el aceite. Sobre el aceite extraído por métodos mecánicos se determinó: perfil de ácidos grasos, clorofilas y carotenoides (espectrofotometría a 670 nm y 472 nm, polifenoles totales (absorbancia a 725 nm y ácidos grasos por cromatografía gaseosa capilar (CGC. Los datos de rendimiento graso (lipogénesis expuestos muestran que no hay diferencias estadísticas entre un riego deficitario que cubre 50% de la Etc y el tratamiento control, tanto en plantas con poda o sin ella. El contenido de polifenoles, clorofilas y carotenoides en los aceites desciende a medida que avanza el estado de madurez de los frutos, independientemente del contenido inicial y el tratamiento. Los tratamientos con riego deficitario (T50% presentan contenidos más elevados de polifenoles (excepto para el muestreo de pre-envero, clorofilas y de carotenoides. No se observan diferencias estadísticamente significativas entre los tratamientos con y sin poda.

  3. A porcine gluteus medius muscle genome-wide transcriptome analysis: dietary effects of omega-6 and omega-3 fatty acids on biological mechanisms

    NARCIS (Netherlands)

    Ogłuszka, Magdalena; Szostak, Agnieszka; Pas, te Marinus F.W.; Poławska, Ewa; Urbański, Paweł; Blicharski, Tadeusz; Pareek, Chandra Shekhar; Juszczuk-Kubiak, Edyta; Dunkelberger, Jenelle R.; Horbańczuk, Jarosław O.; Pierzchała, Mariusz

    2017-01-01


    Background

    The level of omega-6 and omega-3 polyunsaturated fatty acids can affect many cellular systems and function via nuclear receptors or the bioactive lipid regulation of gene expression. The objective of this study was to investigate changes in the muscle transcriptome and the

  4. Fate in digestion in vitro of several food components, including some toxic compounds coming from omega-3 and omega-6 lipids

    NARCIS (Netherlands)

    Goicoechea, E.; Brandon, E.F.A.; Blokland, M.H.; Guillén, M.D.

    2011-01-01

    In this study it was proved the formation of oxygenated alpha,beta-unsaturated aldehydes (OaßUAs) of 6, 7, 9 and 10 carbon atoms during the thermal treatment (190 °C with aeration) of a commercial vegetable oil rich in omega-3 and omega-6 acyl groups, which also contained small amounts of added

  5. Influencia de la alimentación con altos niveles de ácidos grasos insaturados en la calidad de la canal y de la carne de terneros sacrificados a dos niveles de acabado, linoleico, alpha linolenico,

    OpenAIRE

    Alberti Lasalle, Pere; Sañudo Astiz, Carlos; Beriáin Apesteguía, María José

    2012-01-01

    El objetivo fue evaluar el efecto de la inclusión de semilla de lino en el concentrado de terneros sobre los parámetros productivos, en el perfil de ácidos grasos de la grasa intramuscular y en la calidad sensorial y vida útil de la carne. Se utilizaron terneros de raza Pirenaica que fueron cebados con pienso control, o un pienso con un 5% de semilla de lino, o bien con lino y enriquecido con 200 UI de vitamina E, y los animales fueron faenados a dos niveles de engrasamiento. La composición d...

  6. MECANISMOS MOLECULARES POR LOS CUALES LOS ÁCIDOS GRASOS PODRÍAN INFLUIR EN LA CAPTACIÓN DE GLUCOSA Molecular mechanisms by which free fatty acids might interfere with periferic insuline action

    Directory of Open Access Journals (Sweden)

    Clara Eugenia Pérez

    2005-04-01

    Full Text Available Esta revisión tiene el propósito de actualizar el probable mecanismo molecular que ejercen los ácidos grasos en las células que captan glucosa, bajo el estimulo de la insulina y su posible implicación en la diabetes mellitus tipo 2 en la que suelen asociarse resistencia a la insulina, obesidad y síndrome metabólico. Entre los mecanismos moleculares por los cuales un aumento de los ácidos grasos libres podría producir resistencia a la insulina, se encuentra la disminución de los niveles de xilulosa 5-fosfato que bloquea la glucólisis por inhibición de la fosfofructocinasa, ello conduce a un aumento de los productos finales en la vía de las hexosaminas y a la activación de la proteincinasa C, un conocido activador de inhibidor de la cinasa Kappa Beta que inhibe la fosforilación del receptor del sustrato de insulina en tirosina, bloqueando los transportadores de glucosa. Existen investigaciones que sugieren que los ácidos grasos libres están implicados en la insulino-resistencia pero el mecanismo bioquímico no esta dilucidado del todo, pues no hay un mecanismo integral que los relacione o interconecte para concluir determinantemente cómo los altos niveles de ácidos grasos libres inducen la resistencia a la insulina.Previous research suggests that free fatty acids are implicated in insulin resistance, but the molecular mechanism for it isn't completely elucidated, given the lack of an integrated hypothesis relating all of the proposed mechanisms. At the present time, the causes of insulin resistance, obesity and metabolic syndrome, a common feature in patients with diabetes mellitus are matter of intense study. Among several molecular mechanisms by which the increase in free fatty acids could raise insulin resistance is decrease in xylulose-5-phosphate that leads to an inhibition of phosphofructokinase-2, and consequently to a blockade in glycol sis with a subsequent increase in the final products of the hexosamine pathway and

  7. Fermentación in vitro de cebada en función de nivel de inclusión de ácidos grasos en dietas para el cebo de terneros

    OpenAIRE

    Amanzougarene, Z.; Yuste, S.; Vega, A.; Fondevila, M

    2017-01-01

    En dietas para rumiantes en cebo intensivo, así como para vacuno lechero, la adición de grasa en el concentrado permite aumentar la concentración energética y modificar el perfil de ácidos grasos absorbidos, además de atenuar la actividad fermentativa (Palmquist y Jenkins, 1980), contribuyendo a reducir el riesgo de acidosis ruminal. Trabajo financiado con el Proyecto AGL 2013-46820 (MINECO), con la ayuda del Departamento de Industria e Innovación) y el Fondo Social Europeo. S. Yuste disfr...

  8. The use of peracetic acid in drinking water systems: flow tests; L'acido peracetico in potabilizzazione: prove in flusso

    Energy Technology Data Exchange (ETDEWEB)

    Ragazzo, P. [Consorzio per l' Acquedotto del Basso Piave, San Dona' di Piave, VE (Italy); Navazio, G. [Padua Univ., Padua (Italy). Dipt. dei Processi Chimici dell' Ingegneria; Cavadone, A. [Solvay Chimica Italia S.p.A., Milan (Italy)

    2000-09-01

    In a previous research, a preliminary study was carried out on the disinfection efficiency of peracetic acid (PAA), comparing it to that of other disinfectants that are typically used, in batch tests with dosage values ranging from 0.5 to 5 ppm. The study was carried out on samples of water collected from several significant points of the treatment process at the main water treatment plant in Jesolo (Venice, Italy). On the basis of results (basically positive at that time) obtained from these tests, a 400 litre/hour pilot plant was built, as a lower scale reproduction of the drink water treatment system mentioned earlier, in order to study the characteristics of PAA even in tests that could more realistically simulate the flow of water along the process. These tests essentially confirmed the kinetics of the spontaneous hydrolysis to CH{sub 3} COOH+H{sub 2}O{sub 2} and those of dismutation to CH{sub 3}COOH+O{sub 2}, with half-life time values ranging from 3 to 12 hours, depending on the characteristics of the water (especially the pH factor) and the PAA concentration values. [Italian] In un precedente lavoro e' stato effettuato un preventivo studio sull'efficienza disinfettiva dell'acido peracetico, anche in confronto con gli altri piu' usuali disinfettanti, in prove condotte in batch, con dosaggi compresi tra 0.5 e 5 ppm, su campioni di acqua prelevati dai diversi punti significativi della linea di trattamento della centrale di Jesolo (Torre Caligo), gestita dal Consorzio Acquedottistico del Basso Piave di S. Dona' di Piave (Venezia). Sulla base dei risultati, sostanzialmente positivi, e' stato costruito un impianto pilota da 400l/h, riproducente, in scala, la linea di potabilizzazione su ricordata, per studiare le caratteristiche del PAA anche in prove piu' probanti condotte in flusso. In tali prove sono state sostanzialmente riconfermate le cinetiche delle reazioni spontanee di dirolisi a CH{sub 3}COOH+H{sub 2}O{sub 2} e di

  9. Determination of the load state of lead-acid batteries using neural networks; Determinacion del estado de carga de baterias plomo-acido utilizando redes neuronales

    Energy Technology Data Exchange (ETDEWEB)

    Cristin V, Miguel A; Ortega S, Cesar A [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)

    2005-07-01

    The charge of lead-acid batteries (LAB), as in any other type of batteries, consists of replacing the energy consumed during the discharge. Nevertheless, as no physical or chemical process is good enough to totality recharge a battery, it is necessary to supply to it more than the 100% of the energy demanded during its discharge. A critical factor to make a suitable load control of the batteries is to determine its own state of load. That is to say, to have an efficient load control, it is necessary to count on means that allow to accurately determining the residual capacity of the battery to deliver load. This one is the one of the aspects of greater interest in the research centers around world. For this reason, in this work it was pretended to develop a calculation algorithm of the state of load of batteries based on a fuzzy-neural network that could calculate the state of load without using the battery current as an input. This is because one of the main problems for the designers of battery load controllers is the correct supervision of the current that circulates around the system in all the rank of operation of the same one because the sensors do not have a linear behavior. [Spanish] La recarga de baterias plomo-acido (BPA), como cualquier otro tipo de baterias, consiste en reponer la energia consumida durante la descarga. Sin embargo, como ningun proceso fisico o quimico es lo bastante eficiente para recargar a totalidad una bateria, es necesario suministrarle mas del 100% de la energia demandada durante su descarga. Un factor critico para realizar un adecuado control de carga de las baterias, es determinar su propio estado de carga. Es decir, para tener un control de carga eficiente, es necesario contar con un medio que permita determinar con precision la capacidad remanente de la bateria para entregar carga. Este es uno de los aspectos de mayor interes en los centros de investigacion alrededor el mundo. Por tal razon, en este trabajo se propuso

  10. Effects of excedent commercial feed consumption on fatty acid profile from marine fauna aggregated to fish farms = Efectos del consumo de pienso comercial excedente en el perfil de ácidos grasos de la fauna marina agregada a piscifactorías

    OpenAIRE

    González Silvera, Daniel

    2016-01-01

    Objetivos: 1 – Comprobar el posible efecto del consumo de residuos de la acuicultura en diferentes tejidos de distintas especies de peces salvajes agregados a las piscifactorías. 1.1 – El uso de ácidos grasos como marcadores para evaluar el grado de consumo de residuos de la acuicultura por parte de peces salvajes, teniendo en cuenta la distancia a jaulas de piscifactoría. 1.2 – Comprobar el efecto en el perfil de ácidos grasos de peces de distinto nivel trófico. 1.3 – Evaluar la ...

  11. Associations between variants of FADS genes and omega-3 and omega-6 milk fatty acids of Canadian Holstein cows.

    Science.gov (United States)

    Ibeagha-Awemu, Eveline M; Akwanji, Kingsley A; Beaudoin, Frédéric; Zhao, Xin

    2014-02-17

    Fatty acid desaturase 1 (FADS1) and 2 (FADS2) genes code respectively for the enzymes delta-5 and delta-6 desaturases which are rate limiting enzymes in the synthesis of polyunsaturated omega-3 and omega-6 fatty acids (FAs). Omega-3 and-6 FAs as well as conjugated linoleic acid (CLA) are present in bovine milk and have demonstrated positive health effects in humans. Studies in humans have shown significant relationships between genetic variants in FADS1 and 2 genes with plasma and tissue concentrations of omega-3 and-6 FAs. The aim of this study was to evaluate the extent of sequence variations within these two genes in Canadian Holstein cows as well as the association between sequence variants and health promoting FAs in milk. Thirty three SNPs were detected within the studied regions of genes including a synonymous mutation (FADS1-07, rs42187261, 306Tyr > Tyr) in exon 8 of FADS1, a non-synonymous mutation (FADS2-14, rs211580559, 294Ala > Val) within FADS2 exon 7, a splice site SNP (FADS2-05, rs211263660), a 3'UTR SNP (FADS2-23, rs109772589), and another 3'UTR SNP with an effect on a microRNA binding site within FADS2 gene (FADS2-19, rs210169303). Association analyses showed significant relations between three out of seven tested SNPs and several FAs. Significant associations (FDR P FADS2-23 (rs109772589) and two omega-6 FAs (dihomogamma linolenic acid [C20:3n6] and arachidonic acid [C20:4n6]), FADS1-07 (rs42187261) and one omega-3 FA (eicosapentaenoic acid, C20:5n3) and tricosanoic acid (C23:0), and one intronic SNP, FADS1-01 (rs136261927) and C20:3n6. Our study has demonstrated positive associations between three SNPs within FADS1 and FADS2 genes (a SNP within the 3'UTR, a synonymous SNP and an intronic SNP), with three milk PUFAs of Canadian Holstein cows thus suggesting possible involvement of synonymous and non-coding region variants in FA synthesis. These SNPs may serve as potential genetic markers in breeding programs to increase milk FAs that are of

  12. 3w Transmitted Beam Diagnostic at the Omega Laser Facility

    Energy Technology Data Exchange (ETDEWEB)

    Froula, D H; Rekow, V; Sorce, C; Piston, K; Knight, R; Alvarez, S; Griffith, R; Hargrove, D; Ross, J S; Dixit, S; Pollock, B; Divol, L; Glenzer, S H; Armstrong, W; Bahr, R; Thorp, K; Pien, G

    2006-04-24

    A 3{omega} transmitted beam diagnostic has been commissioned on the Omega Laser at the Laboratory for Laser Energetics, University of Rochester [Soures et.al., Laser Part. Beams 11 (1993)]. Transmitted light from one beam is collected by a large focusing mirror and directed onto a diagnostic platform. The near field of the transmitted light is imaged; the system collects information from twice the original f-cone of the beam. Two gated optical cameras capture the near field image of the transmitted light. Thirteen spatial positions around the measurement region are temporally resolved using fast photodiodes to allow a measure of the beam spray evolution. The Forward stimulated Raman scattering and forward simulated Brillion scattering are spectrally and temporally resolved at 5 independent locations within twice the original f-cone. The total transmitted energy is measured in two spectral bands ({delta}{lambda} < 400 nm and {delta}{lambda} > 400 nm).

  13. Estudo da Polarizacao dos Hiperons $\\Xi^-$ E $\\Omega^-$

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho De Gouvea, Andre Luiz [Pontifical Catholic Univ., Rio de Janeiro (Brazil)

    1995-01-01

    ln this thesis the polarization of the $\\Xi^-$ hyperon and the $\\Xi^+$ antihyperon produced in the Fermilab Experiment E791 was determined by the analysis of the weak decay $\\Xi^- \\to \\Lambda^0 + \\pi^-$. For $\\Xi^-$ produced in the interaction between a 500 GeV/c $\\pi^-$ beam and a unpolarized carbon (platinum) target in the region $p_t$ > 0.8 GeV/c and $X_F$ > 0, -10.9% ± 1.5% (-14.7% ± 3.1%) polarization was obtained perpendicular to the production plane and -5.92% ± 1.69% (-2.41%±3.53% $\\approx O$) polarization was measured for $\\Xi^+$. Evidence was also found for a polarized $\\Omega^-$ hyperon produced in the same experiment in the region $X_F$ >0, after analysis of the weak decay $\\Omega^- \\to \\Lambda^0 + K^-$.

  14. Omega Centauri - the glittering giant of the southern skies

    Science.gov (United States)

    2008-12-01

    Omega Centauri is one of the finest jewels of the southern hemisphere night sky, as ESO's latest stunning image beautifully illustrates. Containing millions of stars, this globular cluster is located roughly 17 000 light-years from Earth in the constellation of Centaurus. Omega Centauri ESO PR Photo 44/08 The Glittering Giant Sparkling away at magnitude 3.7 and appearing nearly as large as the full moon on the southern night sky, Omega Centauri is visible with the unaided eye from a clear, dark observing site. Even through a modest amateur telescope, the cluster is revealed as an incredible, densely packed sphere of glittering stars. But astronomers need to use the full power of professional telescopes to uncover the amazing secrets of this beautiful globular cluster. This new image is based on data collected with the Wide Field Imager (WFI), mounted on the 2.2-metre diameter Max-Planck/ESO telescope, located at ESO's La Silla observatory, high up in the arid mountains of the southern Atacama Desert in Chile. Omega Centauri is about 150 light-years across and is the most massive of all the Milky Way's globular clusters. It is thought to contain some ten million stars! Omega Centauri has been observed throughout history. Both the great astronomer Ptolemy and later Johann Bayer catalogued the cluster as a star. It was not until much later, in the early 19th century, that an Englishman, the astronomer John Frederick William Herschel (son of the discoverer of Uranus), realised that Omega Centauri was in fact a globular cluster. Globular clusters are some of the oldest groupings of stars to be found in the halos that surround galaxies like our own Milky Way. Omega Centauri itself is thought to be around 12 billion years old. Recent research into this intriguing celestial giant suggests that there is a medium sized black hole sitting at its centre. Observations made with the Hubble Space Telescope (see heic0809 ) and the Gemini Observatory showed that stars at the

  15. Lipid oxidation in omega-3 emulsions prepared with milk proteins

    DEFF Research Database (Denmark)

    Horn, Anna Frisenfeldt; Nielsen, Nina Skall; Andersen, Ulf

    An increasing body of evidence supports the health beneficial effects of omega-3 polyunsaturated fatty acids. Therefore, incorporation of marine oils into foods has also gained an increasing interest. However, the highly unsaturated lipids present in marine oils are prone to lipid oxidation......, and their addition to foods is therefore limited by the development of unpleasant off-flavors. Hence, efficient strategies are necessary to protect the lipids and thereby make fish oil-enriched food products successful in the marketplace. In an attempt to increase the oxidative stability of fish oil-enriched food....... The properties of the emulsifier used and the structure at the interface are therefore expected to be of great importance for oxidation in emulsions. This presentation will include results from mainly three different studies of lipid oxidation in omega-3 emulsions prepared with milk proteins and protein...

  16. Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology.

    Science.gov (United States)

    Khadge, Saraswoti; Sharp, John Graham; Thiele, Geoffrey M; McGuire, Timothy R; Klassen, Lynell W; Duryee, Michael J; Britton, Holly C; Dafferner, Alicia J; Beck, Jordan; Black, Paul N; DiRusso, Concetta C; Talmadge, James

    2017-10-04

    Recent evidence has suggested that dietary polyunsaturated fatty acids (PUFAs) modulate inflammation; however, few studies have focused on the pathobiology of PUFA using isocaloric and isolipidic diets and it is unclear if the associated pathologies are due to dietary PUFA composition, lipid metabolism or obesity, as most studies compare diets fed ad libitum. Our studies used isocaloric and isolipidic liquid diets (35% of calories from fat), with differing compositions of omega (ω)-6 or long chain (Lc) ω-3 PUFA that were pair-fed and assessed hepatic pathology, inflammation and lipid metabolism. Consistent with an isocaloric, pair-fed model we observed no significant difference in diet consumption between the groups. In contrast, the body and liver weight, total lipid level and abdominal fat deposits were significantly higher in mice fed an ω-6 diet. An analysis of the fatty acid profile in plasma and liver showed that mice on the ω-6 diet had significantly more arachidonic acid (AA) in the plasma and liver, whereas, in these mice ω-3 fatty acids such as eicosapentaenoic acid (EPA) were not detected and docosahexaenoic acid (DHA) was significantly lower. Histopathologic analyses documented that mice on the ω-6 diet had a significant increase in macrovesicular steatosis, extramedullary myelopoiesis (EMM), apoptotic hepatocytes and decreased glycogen storage in lobular hepatocytes, and hepatocyte proliferation relative to mice fed the Lc ω-3 diet. Together, these results support PUFA dietary regulation of hepatic pathology and inflammation with implications for enteral feeding regulation of steatosis and other hepatic lesions. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. A balance of omega-3 and omega-6 polyunsaturated fatty acids is important in pregnancy

    Directory of Open Access Journals (Sweden)

    Olatunji Anthony Akerele

    2016-09-01

    Full Text Available Emerging evidence suggests that omega (n-3 PUFA and their metabolites improve maternal and neonatal health outcomes by modifying gestation length, and reducing the recurrence of pre-term delivery. N-3 PUFA has been associated with prolonged gestation and increased birth dimensions such as birth weight and head circumference. However, mothers giving birth to larger babies are at an increased risk of having dysfunctional labour, genital tract laceration, and delivery via caesarean section. Likewise, high infant weight at birth has been linked to several metabolic and cardiovascular disorders in the offspring. Prolonged gestation also leads to reduced placental function which has been implicated in fetal distress, and perinatal death. Till date, the mechanism through which high n-3 PUFA intake during pregnancy increases gestation length and birth weight is vaguely understood. Early and later stages of pregnancy is characterised by increased production of pro-inflammatory cytokines which are required for pregnancy establishment and labour regulation respectively. Conversely, mid-stage of pregnancy requires anti-inflammatory cytokines necessary for uterine quiescence, pregnancy maintenance and optimal fetal growth. Apparently, changes in the profiles of local cytokines in the uterus during different stages of pregnancy have a profound effect on pregnancy progression. This review focuses on the intake of n-3 and n-6 PUFA during pregnancy and the impact it has on gestation length and infant weight at birth, with a particular emphasis on the expression of inflammatory cytokines required for timely pregnancy establishment (embryo reception and implantation and labour induction. It is concluded that an appropriate dose of n-3 and n-6 PUFA needs to be established during different stages of pregnancy.

  18. Optimization of skewed omega for left-handed material characteristics

    Science.gov (United States)

    Panda, Asit K.; Sahu, Sudhakar; Mishra, Rabindra K.

    2015-01-01

    Artificial neural network and simulated annealing are applied to obtain optimized design parameters of skewed omega-shaped metamaterial unit cells for providing left-handed material (LHM) with a negative refractive index. The implemented numerical and experimental methods provide evidence for the validity and practicality of the technique. Simulation, with optimized parameters, using CST Microwave Studio, shows that skewed LHMs are low-loss materials.

  19. Canadian Consumer Attitudes and Purchasing Behaviour of Omega-3 Products

    OpenAIRE

    Nilsson, Tomas K.H.; Chase, Darren; Emunu, John Paul; McCann-Hiltz, Diane; Peng, Yanning

    2007-01-01

    The development of innovative functional food products is a major trend in today's food industry. The growth of this industry is driven by increased consumer awareness of their own health deficiencies, increased understanding of the possible health benefits of functional foods, development in formulation technologies, a positive regulatory environment and changing consumer demographics and lifestyles. While there has been a proliferation of omega-3 products such as milk, eggs, yogurt, and mar...

  20. Controversies in omega-3 efficacy and novel concepts for application

    OpenAIRE

    Radcliffe, J.E.; Thomas, J; Bramley, A.L.; Kouris-Blazos, A.; B.E. Radford; A.B. Scholey; A. Pipingas; Thomas, C J; Itsiopoulos, C.

    2016-01-01

    Interest in the cardioprotective effects of long chain omega-3 polyunsaturated fatty acids (LCn3) was largely influenced by the low rates of cardiovascular disease (CVD) amongst the Inuits of Greenland who consumed a high marine fat diet rich in LCn3s. This finding stimulated years of epidemiological and clinical studies investigating the cardioprotective effects of LCn3s, thought to be primarily mediated through anti-inflammatory (and anti-aggregatory) prostaglandins that protect the vascula...

  1. Phenolipids as antioxidants in omega-3 enriched food products

    OpenAIRE

    Sørensen, Ann-Dorit Moltke; Aleman, M.; Durand, E.; Villeneuve, P.; Bou, R.; Guardiola, F.; Jacobsen, Charlotte

    2013-01-01

    Foods containing omega-3 PUFA are highly susceptible to oxidation. This causes formation of undesirable flavors and loss of health-beneficial fatty acids. To protect these food products, antioxidant addition may be a solution. Lately, extensive work has been performed on phenolipids and their efficacy in model emulsion systems. Since the polar paradox hypothesis was a simplified statement of the antioxidant efficacy in emulsions, a new term, “cut-off effect”, was introduced. The cut-off effec...

  2. The role of omega-3 fatty acids in child development*

    Directory of Open Access Journals (Sweden)

    Osendarp Saskia JM

    2011-11-01

    Full Text Available Omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFA are important constituents of the maturing brain and therefore considered crucial for brain development in utero and in early infancy. However, it is uncertain whether n-3 LCPUFA supplementation during pregnancy and lactation can have beneficial, sustainable effects on visual or cognitive development. Beneficial effects on child cognitive function after supplementation with EPA and DHA during pregnancy and lactation were observed at 4 years of age, but not at 3, 6 months or 7 years. In term infants LCPUFA when given in relative high dosages, seems to improve visual acuity, but not cognitive function. Evidence for an effect of LCPUFA supplementation of preterm infants remains inconclusive. In children older than 2 years of age, epidemiological evidence suggests an association between psychiatric or neurodevelopmental disorders and omega-3 fatty acid deficiencies. However, the evidence from randomized controlled trials exploring the impact of omega-3 fatty acids on cognitive performance or brain function in school-aged children is not conclusive. In conclusion, n-3 LCPUFA are highly present in the maturing brain and are important for normal brain functioning and development. When provided in relative high dosages, n-3 LCPUFA may improve visual acuity in term infants. However, it remains unclear whether supplementation with n-3 LCPUFA during pregnancy, early infancy, and childhood can improve cognitive function.

  3. Neutron Measurements in Small MagLIF Experiments on OMEGA

    Science.gov (United States)

    Glebov, V. Yu.; Barnak, D. H.; Davies, J. R.; Knauer, J. P.; Betti, R.; Regan, S. P.; Sangster, T. C.; Campbell, E. M.

    2016-10-01

    The Laboratory for Laser Energetics (LLE) is participating in laser-driven magnetized linear inertial fusion (MagLIF) research on the OMEGA Laser System in partnership with Sandia as part of ARPA-E's ALPHA Program. In the current OMEGA setup, a CH cylindrical tube filled with D2 gas is compressed by 40 laser beams, preheated by one of the beams, and an axial magnetic field is applied to limit electron heat loss. Two copper coils provide 10-T magnetic fields. A neutron time-of-flight (nTOF) detector has been designed, fabricated, and calibrated to diagnose primary D-D fusion neutron yield in the range of 1 ×107 to 5 ×109 and ion temperature from 2 to 8 keV. The design details and calibration results of these nTOF detectors will be presented together with neutron measurement results from recent laser-driven MagLIF experiments on OMEGA. The information, data, or work presented herein was funded in part by the Advanced Research Projects Agency-Energy (ARPA-E), U.S. Department of Energy, under Award Number DE-AR0000568, and the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

  4. rho/sup 0/. omega. production in photon photon interactions

    Energy Technology Data Exchange (ETDEWEB)

    Derby, K.A.

    1987-08-01

    The subject of this dissertation is the production of the rho/sup 0/..omega.. final state in photon photon interactions. The production of the rho/sup 0/..omega.. final state has been of interest primarily because of its similarity to the related process ..gamma gamma.. ..-->.. rho/sup 0/rho/sup 0/. The cross section for rho/sup 0/rho/sup 0/ production demonstrates a peaking near threshold, the mechanism of which has been the subject of considerable speculation. The data sample used for the analysis was obtained using the TPC detector facility at the PEP e/sup +/e/sup -/ storage ring, and corresponds to an integrated e/sup +/e/sup -/ luminosity of 64 pb/sup -1/ at 29 GeV center of mass energy. Our estimate of the rho/sup 0/..omega.. cross section is compared to the predictions of several models which have been used to account for the observed rho/sup 0/rho/sup 0/ cross section. The experimental results are consistent with the predictions of a threshold enhancement model, as well as those of a four quark (qq anti q anti q) resonance model. However, they disagree with the predictions of a t-channel factorization approach.

  5. Metathesis process for preparing an alpha, omega-functionalized olefin

    Energy Technology Data Exchange (ETDEWEB)

    Burdett, Kenneth A. (Midland, MI); Mokhtarzadeh, Morteza (Charleston, WV); Timmers, Francis J. (Midland, MI)

    2010-10-12

    A cross-metathesis process for preparing an .alpha.,.omega.-functionalized olefin, such as methyl 9-decenoate, and an .alpha.-olefin having three or more carbon atoms, such as 1-decene. The process involves contacting in a first reaction zone an .alpha.-functionalized internal olefin, such as methyl oleate, and an .alpha.-olefinic monomer having three or more carbon atoms, such as 1-decene, with a first metathesis catalyst to prepare an effluent stream containing the .alpha.,.omega.-functionalized olefin, such as methyl 9-decenoate, an unfunctionalized internal olefin, such as 9-octadecene, unconverted reactant olefins, and optionally, an .alpha.,.omega.-difunctionalized internal olefinic dimer, such as dimethyl 9-octadecen-1,18-dioate; separating said effluent streams; then contacting in a second reaction zone the unfunctionalized internal olefin with ethylene in the presence of a second metathesis catalyst to obtain a second product effluent containing the .alpha.-olefinic monomer having three or more carbon atoms; and cycling a portion of the .alpha.-olefinic monomer stream(s) to the first zone.

  6. Omega-3 fatty acids: role in metabolism and cardiovascular disease.

    Science.gov (United States)

    Gerber, Philipp A; Gouni-Berthold, Ioanna; Berneis, Kaspar

    2013-01-01

    The inverse association of cardiovascular risk with intake of omega-3 polyunsaturated fatty acids was suspected early in populations that are known to have a high consumption of fish and fish oil. Subsequent cohort studies confirmed such associations in other populations. Further evidence of possible beneficial effects on metabolism and cardiovascular health was provided by many studies that were able to show specific mechanisms that may underlie these observations. These include improvement of the function of tissues involved in the alterations occurring during the development of obesity and the metabolic syndrome, as adipose tissue, the liver and skeletal muscle. Direct action on the cardiovascular system was not only shown regarding vascular function and the formation of atherosclerotic plaques, but also by providing antiarrhythmic effects on the heart. Data on these effects come from in vitro as well as in vivo studies that were conducted in animal models of disease, in healthy humans and in humans suffering from cardiovascular disease. To define prophylactic as well as treatment options in primary and secondary prevention, large clinical trial assessed the effect of omega-3 polyunsaturated fatty acids on end points as cardiovascular morbidity and mortality. However, so far these trials provided ambiguous data that do allow recommendations regarding the use of omega-3 polyunsaturated fatty acids in higher dosages and beyond the dietary advice of regular fish intake only in few clinical situations, such as severe hypertriglyceridemia.

  7. Exclusive $\\omega$ meson muoproduction on transversely polarised protons

    CERN Document Server

    Adolph, C.; Aghasyan, M.; Akhunzyanov, R.; Alexeev, M.G.; Alexeev, G.D.; Amoroso, A.; Andrieux, V.; Anfimov, N.V.; Anosov, V.; Augustyniak, W.; Austregesilo, A.; Azevedo, C.D.R.; Badelek, B.; Balestra, F.; Barth, J.; Beck, R.; Bedfer, Y.; Bernhard, J.; Bicker, K.; Bielert, E.R.; Birsa, R.; Bisplinghoff, J.; Bodlak, M.; Boer, M.; Bordalo, P.; Bradamante, F.; Braun, C.; Bressan, A.; Buechele, M.; Chang, W. -C.; Chatterjee, C.; Chiosso, M.; Choi, I.; Chung, S. -U.; Cicuttin, A.; Crespo, M.L.; Curiel, Q.; Dalla Torre, S.; Dasgupta, S.S.; Dasgupta, S.; Denisov, O. Yu.; Dhara, L.; Donskov, S.V.; Doshita, N.; Duic, V.; Duennweber, W.; Dziewiecki, M.; Efremov, A.; Eversheim, P.D.; Eyrich, W.; Faessler, M.; Ferrero, A.; Finger, M.; Fischer, H.; Franco, C.; von Hohenesche, N. du Fresne; Friedrich, J.M.; Frolov, V.; Fuchey, E.; Gautheron, F.; Gavrichtchouk, O.P.; Gerassimov, S.; Giordano, F.; Gnesi, I.; Gorzellik, M.; Grabmueller, S.; Grasso, A.; Grosse Perdekamp, M.; Grube, B.; Grussenmeyer, T.; Guskov, A.; Haas, F.; Hahne, D.; von Harrach, D.; Hashimoto, R.; Heinsius, F.H.; Heitz, R.; Herrmann, F.; Hinterberger, F.; Horikawa, N.; dHose, N.; Hsieh, C. -Y.; Huber, S.; Ishimoto, S.; Ivanov, A.; Ivanshin, Yu.; Iwata, T.; Jahn, R.; Jary, V.; Joosten, R.; Joerg, P.; Kabuss, E.; Ketzer, B.; Khaustov, G.V.; Khokhlov, Yu. A.; Kisselev, Yu.; Klein, F.; Klimaszewski, K.; Koivuniemi, J.H.; Kolosov, V.N.; Kondo, K.; Koenigsmann, K.; Konorov, I.; Konstantinov, V.F.; Kotzinian, A.M.; Kouznetsov, O.M.; Kraemer, M.; Kremser, P.; Krinner, F.; Kroumchtein, Z.V.; Kulinich, Y.; Kunne, F.; Kurek, K.; Kurjata, R.P.; Lednev, A.A.; Lehmann, A.; Levillain, M.; Levorato, S.; Lian, Y. -S.; Lichtenstadt, J.; Longo, R.; Maggiora, A.; Magnon, A.; Makins, N.; Makke, N.; Mallot, G.K.; Marchand, C.; Marianski, B.; Martin, A.; Marzec, J.; Matousek, J.; Matsuda, H.; Matsuda, T.; Meshcheryakov, G.V.; Meyer, M.; Meyer, W.; Michigami, T.; Mikhailov, Yu. V.; Mikhasenko, M.; Mitrofanov, E.; Mitrofanov, N.; Miyachi, Y.; Montuenga, P.; Nagaytsev, A.; Nerling, F.; Neyret, D.; Nikolaenko, V.I.; Novy, J.; Nowak, W.D.; Nukazuka, G.; Nunes, A.S.; Olshevsky, A.G.; Orlov, I.; Ostrick, M.; Panzieri, D.; Parsamyan, B.; Paul, S.; Peng, J. -C.; Pereira, F.; Pesek, M.; Peshekhonov, D.V.; Pierre, N.; Platchkov, S.; Pochodzalla, J.; Polyakov, V.A.; Pretz, J.; Quaresma, M.; Quintans, C.; Ramos, S.; Regali, C.; Reicherz, G.; Riedl, C.; Roskot, M.; Ryabchikov, D.I.; Rybnikov, A.; Rychter, A.; Salac, R.; Samoylenko, V.D.; Sandacz, A.; Santos, C.; Sarkar, S.; Savin, I.A.; Sawada, T.; Sbrizzai, G.; Schiavon, P.; Schmidt, K.; Schmieden, H.; Schoenning, K.; Schopferer, S.; Seder, E.; Selyunin, A.; Shevchenko, O. Yu.; Silva, L.; Sinha, L.; Sirtl, S.; Slunecka, M.; Smolik, J.; Sozzi, F.; Srnka, A.; Steffen, D.; Stolarski, M.; Sulc, M.; Suzuki, H.; Szabelski, A.; Szameitat, T.; Sznajder, P.; Takekawa, S.; Tasevsky, M.; Tessaro, S.; Tessarotto, F.; Thibaud, F.; Tosello, F.; Tskhay, V.; Uhl, S.; Veloso, J.; Virius, M.; Vondra, J.; Wallner, S.; Weisrock, T.; Wilfert, M.; ter Wolbeek, J.; Zaremba, K.; Zavada, P.; Zavertyaev, M.; Zemlyanichkina, E.; Ziembicki, M.; Zink, A.

    2017-01-01

    Exclusive production of $\\omega$ mesons was studied at the COMPASS experiment by scattering $160~\\mathrm{GeV}/\\mathit{c}$ muons off transversely polarised protons. Five single-spin and three double-spin azimuthal asymmetries were measured in the range of photon virtuality $1~(\\mathrm{GeV}/\\mathit{c})^2 < Q^2 < 10~(\\mathrm{GeV}/\\mathit{c})^2$, Bjorken scaling variable $0.003 < x_{\\mathit{Bj}} < 0.3$ and transverse momentum squared of the $\\omega$ meson $0.05~(\\mathrm{GeV}/\\mathit{c})^2 < p_{T}^{2} < 0.5~(\\mathrm{GeV}/\\mathit{c})^2$. The measured asymmetries are sensitive to the nucleon helicity-flip Generalised Parton Distributions (GPD) $E$ that are related to the orbital angular momentum of quarks, the chiral-odd GPDs $H_{T}$ that are related to the transversity Parton Distribution Functions, and the sign of the $\\pi\\omega$ transition form factor. The results are compared to recent calculations of a GPD-based model.

  8. The MicrOmega Investigation Onboard Hayabusa2

    Science.gov (United States)

    Bibring, J.-P.; Hamm, V.; Langevin, Y.; Pilorget, C.; Arondel, A.; Bouzit, M.; Chaigneau, M.; Crane, B.; Darié, A.; Evesque, C.; Hansotte, J.; Gardien, V.; Gonnod, L.; Leclech, J.-C.; Meslier, L.; Redon, T.; Tamiatto, C.; Tosti, S.; Thoores, N.

    2017-07-01

    MicrOmega is a near-IR hyperspectral microscope designed to characterize in situ the texture and composition of the surface materials of the Hayabusa2 target asteroid. MicrOmega is implemented within the MASCOT lander (Ho et al. in Space Sci. Rev., 2016, this issue, doi:10.1007/s11214-016-0251-6). The spectral range (0.99-3.65 μm) and the spectral sampling (20 cm^{-1}) of MicrOmega have been chosen to allow the identification of most potential constituent minerals, ices and organics, within each 25 μm pixel of the 3.2× 3.2 mm2 FOV. Such an unprecedented characterization will (1) enable the identification of most major and minor phases, including the potential organic phases, and ascribe their mineralogical context, as a critical set of clues to decipher the origin and evolution of this primitive body, and (2) provide the ground truth for the orbital measurements as well as a reference for the analyses later performed on returned samples.

  9. Proposal to neutralize acid fluids from wells in the Los Humeros, Pue., geothermal field; Propuesta para la neutralizacion de fluidos acidos provenientes de pozos del campo geotermico de Los Humeros, Pue.

    Energy Technology Data Exchange (ETDEWEB)

    Flores Armenta, Magaly del Carmen; Ramirez Montes, Miguel; Garcia Cuevas, Juan Manuel [Comision Federal de Electricidad, Gerencia de Proyectos Geotermoelectricos, Morelia, Michoacan (Mexico)]. E-mail: magaly.flores@cfe.gob.mx

    2009-07-15

    Neutralizing an acidic fluid consists of adding a sodium hydroxide solution to neutralize the H group of acids, therefore increasing the pH. The injection of sodium hydroxide has to be continuous and at a proper depth inside the well to protect against the corrosion of casing and surface equipment. Neutralization is a common practice used in geothermal fields, such as at The Geysers in the US and Miravalles in Costa Rica-places where aggressive fluids cause problems for extracting and using geothermal fluids commercially. A zone surrounding wells H-4, H-16 and H-29 in the northern section of the Los Humeros, Pue., geothermal field, known as the Colapso Central, has shown evidence of aggressively acidic fluids. Several wells drilled in the area had to be repaired, thus plugging and isolating the deepest production zones. Well H-43 was drilled two years ago in the northern zone of the field, and even though it is not located in the aggressive-fluid zone, the well presents mineralogical features possibly indicating the presence of acidic fluids. Therefore, before producing this well it has been proposed we install a neutralization system with general characteristics presented in this paper. The system will prevent corrosion that up to now has prevented exploitation of the deep portion of Colapso Central, helping to develop the field in a more profitable way. [Spanish] Neutralizar un fluido acido consiste en agregarle una solucion de hidroxido de sodio. Esto neutraliza el grupo de acidos H y en consecuencia aumenta el pH. La inyeccion de hidroxido de sodio se realiza de manera continua y a una profundidad adecuada dentro del pozo para proteger a la tuberia y a todo el equipo superficial contra la corrosion. La neutralizacion es una practica comun que se viene realizando en campos como Los Geysers en Estados Unidos y en Miravalles, Costa Rica, donde la presencia de fluidos agresivos causa problemas en la extraccion y aprovechamiento del fluido geotermico con fines

  10. Bioavailability of Dietary Omega-3 Fatty Acids Added to a Variety of Sausages in Healthy Individuals.

    Science.gov (United States)

    Köhler, Anton; Heinrich, Johanna; von Schacky, Clemens

    2017-06-19

    A low Omega-3 Index (eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in erythrocytes) is associated with cardiac, cerebral, and other health issues. Intake of EPA and DHA, but not of alpha-linolenic acid (ALA), increases the Omega-3 Index. We investigated bioavailability, safety, palatability and tolerability of EPA and DHA in a novel source: a variety of sausages. We screened 96 healthy volunteers, and recruited 44 with an Omega-3 Index Omega-3 Index increased from 4.18 ± 0.54 to 5.72 ± 0.66% (p Omega-3 Index per intake of EPA and DHA we observed was higher than for other sources previously studied, indicating superior bioavailability. As increasing production of EPA and DHA is difficult, improvements of bioavailability can facilitate reaching the target range for the Omega-3 Index (8-11%).

  11. In-medium modifications of the {omega} meson near the production threshold

    Energy Technology Data Exchange (ETDEWEB)

    Thiel, M.; Metag, V.; Berghaeuser, H.; Drexler, P.; Friedrich, S.; Gregor, R.; Kotulla, M.; Lugert, S.; Nanova, M.; Novotny, R.W. [University of Giessen, II. Physikalisches Institut, Giessen (Germany); Aguar Bartolome, P.; Akasoy, L.K.; Arends, H.J.; Heid, E.; Jahn, O.; Martinez, M.; Middleton, D.G.; Ostrick, M.; Schumann, S.; Thomas, A.; Unverzagt, M. [University of Mainz, Institut fuer Kernphysik, Mainz (Germany); Annand, J.R.M.; Livingston, K.; MacGregor, I.J.D.; Mancell, J.; McGeorge, J.C.; McNicoll, E.F.; Robinson, J.; Rosner, G. [University of Glasgow, SUPA, School of Physics and Astronomy, Glasgow (United Kingdom); Bantawa, K.; Manley, D.M. [Kent State University, Kent, Ohio (United States); Beck, R. [University of Mainz, Institut fuer Kernphysik, Mainz (Germany); University Bonn, Helmholtz-Institut fuer Strahlen- und Kernphysik, Bonn (Germany); Bekrenev, V.; Kulbardis, A. [Petersburg Nuclear Physics Institute, Gatchina (Russian Federation); Braghieri, A.; Pedroni, P. [INFN Sezione di Pavia, Pavia (Italy); Briscoe, W.J. [The George Washington University, Center for Nuclear Studies, Washington, DC (United States); Brudvik, J.; Nefkens, B.M.K.; Prakhov, S.N.; Starostin, A. [University of California Los Angeles, Los Angeles, California (United States); Cherepnya, S.; Fil' kov, L.V. [Lebedev Physical Institute, Moscow (Russian Federation); Dieterle, M.; Keshelashvili, I.; Krusche, B.; Maghrbi, Y.; Pheron, F.; Rostomyan, T.; Werthmueller, D. [University of Basel, Department of Physics, Basel (Switzerland); Downie, E.J. [University of Mainz, Institut fuer Kernphysik, Mainz (Germany); The George Washington University, Center for Nuclear Studies, Washington, DC (United States); Glazier, D.I.; Jude, T.C.; Sikora, M.H.; Watts, D.P. [University of Edingburgh, SUPA, School of Physics, Edinburgh (United Kingdom); Hornidge, D. [Mount Allison University, New Brunswick (Canada); Kashevarov, V.L. [University of Mainz, Institut fuer Kernphysik, Mainz (Germany); Lebedev Physical Institute, Moscow (Russian Federation); Kondratiev, R.; Lisin, V.; Polonski, A. [Institute for Nuclear Research, Moscow (Russian Federation); Korolija, M.; Supek, I.; Zamboni, I. [Rudjer Boskovic Institute, Zagreb (Croatia); Lemmer, B. [University of Giessen, II. Physikalisches Institut, Giessen (Germany); University of Goettingen, II. Physikalisches Institut, Goettingen (Germany); Mushkarenkov, A. [University of Massachusetts Amherst, Amherst, MA (United States); Nikolaev, A. [University Bonn, Helmholtz-Institut fuer Strahlen- und Kernphysik, Bonn (Germany); Weil, J. [University of Giessen, Institut fuer Theoretische Physik, Giessen (Germany)

    2013-10-15

    The in-medium properties of the {omega} meson were investigated at the MAMI-C electron accelerator using the Crystal Ball/TAPS detector system to identify {omega} mesons through their {omega} {yields} {pi}{sup 0} {gamma} decay channel. Two solid targets (C, Nb) and a LH{sub 2} target as a reference have been used. In the energy range 900 to 1300 MeV the {omega} lineshapes for the different nuclei are compared and a broadening of the {omega} signal for the niobium target is observed in comparison to the liquid-hydrogen target. In a second analysis the {omega} momentum distributions for the solid targets are determined for 50 MeV/c wide bins. For both analyses a comparison to transport calculations shows that the data are consistent with an in-medium modification by collisional broadening, as observed by transparency ratio measurements. (orig.)

  12. Coherent phase control in ionization of Magnesium by a bichromatic laser field of frequencies \\omega and 2\\omega

    CERN Document Server

    Buica-Zloh, Gabriela; 10.1140/epjd/e2004-00034-2

    2013-01-01

    We have investigated the coherent phase control on the (3p^{2}) autoionizing state (AIS) resonantly coupled with the ground state for Mg through a two- and a four-photon transition simultaneously, using a bichromatic linearly polarized laser field. The frequency is chosen such that the lasers are tunable around resonance with the transition (3s^{2}(^{1}S^e)\\rightarrow 3p^{2}(^{1}S^e)), which implies (\\omega_{f}=2.11) eV and (\\omega_{h}=4.22) eV. We are interested in the modification of autoionizing (AI) line shape through the relative phase and laser intensities. A strong phase dependence on the total ionization yield and ionization rate is found. We also performed a time-dependent calculation which takes into consideration all the resonant states of the process.

  13. Potential Benefits of Omega-3 Fatty Acids in Non-Melanoma Skin Cancer

    OpenAIRE

    Black, Homer S.; Rhodes, Lesley E.

    2016-01-01

    Considerable circumstantial evidence has accrued from both experimental animal and human clinical studies that support a role for omega-3 fatty acids (FA) in the prevention of non-melanoma skin cancer (NMSC). Direct evidence from animal studies has shown that omega-3 FA inhibit ultraviolet radiation (UVR) induced carcinogenic expression. In contrast, increasing levels of dietary omega-6 FA increase UVR carcinogenic expression, with respect to a shorter tumor latent period and increased tumor ...

  14. OMEGA-3 FATTY ACIDS AND AGE-RELATED DISEASES: REALITIES AND PROSPECTS

    Directory of Open Access Journals (Sweden)

    O. M. Drapkina

    2015-09-01

    Full Text Available Efficacy of omega-3 fatty acids in cardiology is so high that in many countries omega-3 fatty acids are included into the treatment protocols for patients with cardiovascular diseases. This therapeutic class slows down oxidative stress and chronic inflammation processes, thereby providing a significant contribution to the complex treatment of hypertension. Besides, omega-3 fatty acids slow down the aging process and prevent the development of age-related diseases affecting the rate of telomere shortening.

  15. Induction of (omega-1)-oxidation of monocarboxylic acids by acetylsalicylic acid.

    Science.gov (United States)

    Kundu, R K; Getz, G S; Tonsgard, J H

    1993-07-01

    Monocarboxylic acids may be oxidized at the omega- and (omega-1)- positions to form dicarboxylic acids (DCAs) and (omega-1)-hydroxy- or (omega-1)-oxoacids. The significance of this pathway under normal conditions is unknown, but DCAs and (omega-1)-hydroxyacids are prominent features of disease states. The stimulation of this pathway has been linked to induction of fatty acid-binding protein and peroxisomal proliferation. In this study, we examined the effect of acetylsalicylic acid (ASA) on (omega-1)-oxidation. (Omega-1)-oxidation was assessed in subcellular fractions of rat liver. Rats were fed a normal diet or an ASA-supplemented diet. Products were identified by gas chromatography-mass spectrometry (GC-MS) and by comparison with the properties of authentic synthetic standards. Doses of ASA that produced relatively low serum concentrations (12-24 mg/dl) resulted in as much as a 20-fold increase in the capacity for (omega-1)-oxidation of medium (C12-C15) and long chain (C16-C20) monocarboxylic acids. Normal rat liver oxidizes monocarboxylic acids to (omega-1)-oxoacids, while liver from ASA-treated rats converts these substrates to (omega-1)-oxodicarboxylic acids and (omega-1)-oxoacids. The formation of oxoacids and oxodicarboxylic acids may be due to different enzymes. The formation of oxodicarboxylic acids appears to be more labile than the formation of oxoacids. These two processes also are differentially induced by ASA and have different substrate specificities. These results demonstrate that ASA is a potent stimulant of (omega-1)-oxidation and induces the formation of products that can be shortened in peroxisomes to key metabolic intermediates.

  16. OMEGA-3 FATTY ACIDS AND AGE-RELATED DISEASES: REALITIES AND PROSPECTS

    Directory of Open Access Journals (Sweden)

    O. M. Drapkina

    2015-01-01

    Full Text Available Efficacy of omega-3 fatty acids in cardiology is so high that in many countries omega-3 fatty acids are included into the treatment protocols for patients with cardiovascular diseases. This therapeutic class slows down oxidative stress and chronic inflammation processes, thereby providing a significant contribution to the complex treatment of hypertension. Besides, omega-3 fatty acids slow down the aging process and prevent the development of age-related diseases affecting the rate of telomere shortening.

  17. Stability and Stabilization of Omega-3 Oils as such and in Selected Foods

    OpenAIRE

    Jacobsen, Charlotte

    2012-01-01

    The application of omega-3 polyunsaturated fatty acids (PUFA) in foods has increased dramatically during the last decade due to the increasing awareness about the health beneficial effects of these fatty acids. Due to their polyunsaturated nature omega-3 PUFA are highly susceptible to lipid oxidation, which will lead to formation of undesirable fishy and rancid off-flavours. Such off-flavours can lead to consumer rejection of omega-3 enriched foods. Important issues to address in order to avo...

  18. The Secondary Standards programme for OmegaCAM at the VST

    OpenAIRE

    Kleijn, Gijs Verdoes; Vermeij, Ronald; Valentijn, Edwin; Kuijken, Koen

    2006-01-01

    The OmegaCAM wide-field imager will start operations at the ESO VLT Survey Telescope at Paranal, Chile, in 2007. The photometric calibration of OmegaCAM data depends on standard star measurements that cover the complete 1 square degree FoV of OmegeaCAM. A catalog fullfilling this requirement for eight Landolt equatorial fields, denoted the OmegaCAM Secondary Standards Catalog, will be constructed from OmegaCAM observations during the first year of operations. Here we present the 'Preliminary ...

  19. Potential Benefits of Omega-3 Fatty Acids in Non-Melanoma Skin Cancer.

    Science.gov (United States)

    Black, Homer S; Rhodes, Lesley E

    2016-02-04

    Considerable circumstantial evidence has accrued from both experimental animal and human clinical studies that support a role for omega-3 fatty acids (FA) in the prevention of non-melanoma skin cancer (NMSC). Direct evidence from animal studies has shown that omega-3 FA inhibit ultraviolet radiation (UVR) induced carcinogenic expression. In contrast, increasing levels of dietary omega-6 FA increase UVR carcinogenic expression, with respect to a shorter tumor latent period and increased tumor multiplicity. Both omega-6 and omega-3 FA are essential FA, necessary for normal growth and maintenance of health and although these two classes of FA exhibit only minor structural differences, these differences cause them to act significantly differently in the body. Omega-6 and omega-3 FA, metabolized through the lipoxygenase (LOX) and cyclooxygenase (COX) pathways, lead to differential metabolites that are influential in inflammatory and immune responses involved in carcinogenesis. Clinical studies have shown that omega-3 FA ingestion protects against UVR-induced genotoxicity, raises the UVR-mediated erythema threshold, reduces the level of pro-inflammatory and immunosuppressive prostaglandin E2 (PGE₂) in UVR-irradiated human skin, and appears to protect human skin from UVR-induced immune-suppression. Thus, there is considerable evidence that omega-3 FA supplementation might be beneficial in reducing the occurrence of NMSC, especially in those individuals who are at highest risk.

  20. Potential Benefits of Omega-3 Fatty Acids in Non-Melanoma Skin Cancer

    Directory of Open Access Journals (Sweden)

    Homer S. Black

    2016-02-01

    Full Text Available Considerable circumstantial evidence has accrued from both experimental animal and human clinical studies that support a role for omega-3 fatty acids (FA in the prevention of non-melanoma skin cancer (NMSC. Direct evidence from animal studies has shown that omega-3 FA inhibit ultraviolet radiation (UVR induced carcinogenic expression. In contrast, increasing levels of dietary omega-6 FA increase UVR carcinogenic expression, with respect to a shorter tumor latent period and increased tumor multiplicity. Both omega-6 and omega-3 FA are essential FA, necessary for normal growth and maintenance of health and although these two classes of FA exhibit only minor structural differences, these differences cause them to act significantly differently in the body. Omega-6 and omega-3 FA, metabolized through the lipoxygenase (LOX and cyclooxygenase (COX pathways, lead to differential metabolites that are influential in inflammatory and immune responses involved in carcinogenesis. Clinical studies have shown that omega-3 FA ingestion protects against UVR-induced genotoxicity, raises the UVR-mediated erythema threshold, reduces the level of pro-inflammatory and immunosuppressive prostaglandin E2 (PGE2 in UVR-irradiated human skin, and appears to protect human skin from UVR-induced immune-suppression. Thus, there is considerable evidence that omega-3 FA supplementation might be beneficial in reducing the occurrence of NMSC, especially in those individuals who are at highest risk.

  1. The potential of omega-3 fatty acids in the prevention of non-melanoma skin cancer.

    Science.gov (United States)

    Black, Homer S; Rhodes, Lesley E

    2006-01-01

    In toto, there is strong circumstantial evidence from both experimental and clinical studies to support a role for omega-3 FA in the prevention of non-melanoma skin cancer (NMSC). In experimental animal studies there is direct evidence that dietary omega-3 FA inhibits ultraviolet radiation (UVR) carcinogenic expression, with regard to both increased tumor latent period and reduced tumor multiplicity. Equivalent levels of omega-6 FA increase UVR carcinogenic expression. Dietary omega-3 FA dramatically reduces the plasma and cutaneous pro-inflammatory and immunosuppressive PGE(2) levels in mice. Dietary omega-6 FA increases prostaglandin E synthase type 2 (PGE(2)) level. Dietary omega-3 FA significantly reduces the inflammatory response and sustains, or enhances, the delayed type hypersensitivity immune response in mice when compared to an equivalent dietary level of omega-6 FA. Supplementary omega-3 FA significantly increases the UVR-mediated erythema threshold in humans. Supplementary omega-3 FA significantly reduces the level of pro-inflammatory and immunosuppressive PGE(2) levels in Ultraviolet B-irradiated human skin.

  2. Efecto de diferentes métodos de extracción sobre el perfil de ácidos grasos en el aceite de aguacate (Persea americana Mill. var. Hass

    Directory of Open Access Journals (Sweden)

    Arturo Martínez Zavala

    2011-01-01

    Full Text Available El objetivo de este estudio fue evaluar la posible formación de ácidos grasos trans (AGT en el aceite de aguacate, extraído con disolvente (hexano, con y sin calor, y por centrifugación. Para analizar el aceite se emplearon índices químicos, y para la identificación y cuantificación de los ácidos grasos se utilizó Espectroscopía de Infrarrojo con Transformada de Fourier (EITF, en la región media de 400 a 4000 cm E-1 y cromatografía de gases. En los resultados del análisis por EITF se demostró que los tres aceites presentaron un pico definido en la región de 968 cm E-1 que corresponde a los dobles enlaces trans. Los AGT se cuantificaron < 0,5 g/100 g de aceite, valores menores que el propuesto por The Danish Veterinary and Food Administration para considerar un aceite libre de AGT. De acuerdo con los índices químicos, el método que causó la mínima modificación en la calidad del aceite fue el de extracción por centrifugación.

  3. Efecto de diferentes métodos de extracción sobre el perfil de ácidos grasos en el aceite de aguacate (Persea americana Mill. var. Hass

    Directory of Open Access Journals (Sweden)

    José Alberto Ariza Ortega

    2011-12-01

    Full Text Available El objetivo de este estudio fue evaluar la posible formación de ácidos grasos trans (AGT en el aceite de aguacate, extraído con disolvente (hexano, con y sin calor, y por centrifugación. Para analizar el aceite se emplearon índices químicos, y para la identificación y cuantificación de los ácidos grasos se utilizó Espectroscopía de Infrarrojo con Transformada de Fourier (EITF, en la región media de 400 a 4000 cm-1 y cromatografía de gases. En los resultados del análisis por EITF se demostró que los tres aceites presentaron un pico definido en la región de 968 cm-1 que corresponde a los dobles enlaces trans. Los AGT se cuantificaron < 0,5 g/100 g de aceite, valores menores que el propuesto por The Danish Veterinary and Food Administration para considerar un aceite libre de AGT. De acuerdo con los índices químicos, el método que causó la mínima modificación en la calidad del aceite fue el de extracción por centrifugación.

  4. HUBUNGAN ASUPAN DAN KADAR OMEGA-3 PLASMA DENGAN KEJADIAN HIPERTENSI PADA ETNIK MINANGKABAU DI KOTA PADANG

    Directory of Open Access Journals (Sweden)

    Delmi Sulastri

    2010-09-01

    Full Text Available AbstrakHipertensi merupakan masalah kesehatan utama di Indonesia maupun di dunia Hampir 95% kasus hipertensi tidak diketahui penyebabnya atau disebut hipertensi esensial (HET. Pola konsumsi yang baik dan seimbang merupakan salah satu upaya pengendalikan tekanan darah. Omega-3 adalah salah satu zat gizi yang dapat menurunkan tekanan darah. Omega-3, terbukti berperan dalam mencegah beberapa penyakit kronis termasuk hipertensi.Telah dilakukan penelitian dengan desain cross sectional study untuk melihat hubungan omega-3 plasma dengan kejadian hipertensi. Penelitian dilakukan pada 130 orang yang terdiridari subjek hipertensi dan normotensi. Pengambilan sampel dengan cara sistematik random sampling dengan memperhatikan kriteria inklusi dan ekslusi. Asupan omega-3 dihitung menggunakan FFQ dan kadar omega-3 plasma diukur dengan teknik methylasi.Hasil penelitian ini adalah asupan omega-3 adalah 0,66±0,61 gram/hari, EPA 0,29 ± 0,23 gram/hari, DHA (22:6 0,85± 0,65 gram/hari dan kelompok normotensi ALA 0,64± 0,55 gram/hari, EPA 0,27±0,15 gram/hari, DHA 21,34 ± 174,14 gram/hari. Tidak terdapat perbedaan bermakna asupan omega-3 dengan kadar omega-3 plasma antara kelompok hipertensi dengan kelompok normotensi dan tidak terdapat hubungan yang bermakna antara asupan omega-3 dan kadar omega-3 plasma dengan kejadian hipertensi.Hasil penelitian ini tidak mendukung hubungan antara omega-3 dengan kejadian hipertensiKata kunci : hipertensi, omega-3, EPA, ALA, DHAAbstractHypertension is the leading health problem in the community in Indonesia and even in certain countries all over the world. Almost 95% of hypertension cases are from unknown cause which is also known as essential hypertension (HET. Planned and balanced consumption pole is one of the efforts to control blood pressure. Omega-3 is one of the nutrients that reduce blood pressure. Omega-3 is proven to involve in preventing certain chronic disease including hypertension.A cross-sectional study carried

  5. Ácidos grasos, vitamina e y rotulado nutricional de margarinas y esparcibles comercializados en Bogotá, Colombia Fatty acids, vitamin E and nutritional labeling of margarines and spreads commercialized in Bogota, Colombia

    Directory of Open Access Journals (Sweden)

    Lorena A Bolívar C

    2010-06-01

    Full Text Available INTRODUCCIÓN: en Colombia es escasa la información sobre el contenido de ácidos grasos y vitaminas en margarinas y esparcibles comercializados en el ámbito local. OBJETIVO: analizar el perfil de ácidos grasos y de vitamina E de las margarinas y esparcibles más comercializados en Bogotá, Colombia, y su situación actual de rotulado nutricional según la Resolución 0288 de 2008. MATERIALES Y MÉTODOS: en 2008 se realizó un conteo de caras de las margarinas y esparcibles más comercializados en supermercados de cadena de cinco localidades de Bogotá que incluyeron diferentes estratos socioeconómicos, y se escogieron las primeras diecisiete marcas comerciales y tres marcas propias para el estudio. De cada producto se tomaron y analizaron cinco repeticiones, una por localidad, entre agosto y noviembre de 2008. RESULTADOS: los ácidos grasos mayoritarios son palmítico, oleico y linoleico, y cuatro productos son fuente de ácidos grasos trans (4,4 g y 6,9 g/100 g. El contenido de vitamina E varía de 2,3 mg a 39,9 mg/100 g de producto. De 74,3% a 96,2% de los nutrientes de declaración obligatoria son efectivamente declarados en la etiqueta de los productos analizados. RESULTADOS: 91% de las margarinas y esparcibles más comercializados en cinco localidades de Bogotá en agosto de 2008 es libre de ácidos grasos trans (INTRODUCTION: information on the content of fatty acids and vitamins in margarines and spreads locally commercialized in Colombia is scarse. OBJECTIVE: analyze the fatty acids and vitamin E profile in margarines and spreads most commercialized in Bogotá, Colombia and its current nutritional labeling under Resolution 0288 of 2008. MATERIALS AND METHODS: a counting of labels of margarines and spreads most commercialized in chain supermarkets of five localities in Bogotá that included different socio-economical strata, was made. The first seventeen trademarks and three study brand marks were chosen for the study. Five samples

  6. CAMBIOS EN LOS ÁCIDOS GRASOS DE MEMBRANA DE Microbacterium esteraromaticum GNP5 CON DIFERENTES TEMPERATURAS Y OSMOLARIDADES Changes in Membrane Fatty Acids of Microbacterium esteraromaticum GNP5 with Changes of Temperature and Osmolarity

    Directory of Open Access Journals (Sweden)

    GRACIELA NATALIA PUCCI

    2006-06-01

    Full Text Available Microbacterium esteraromaticum es un microorganismo que se aísla con frecuencia de landfarming o procesos de biorremediación de hidrocarburos en la meseta de la Patagonia central (Argentina y se halla sometido a variaciones de temperatura y a cambios de salinidad que se producen naturalmente. Su adaptabilidad a esos cambios climáticos indujo al estudio de las modificaciones que se producen en su membrana celular para resistirlos. En este trabajo se estudió el efecto conjunto de la temperatura y la concentración de cloruro de sodio sobre la composición de los ácidos grasos de membrana en la cepa de Microbacterium esteraromaticum GNP5b. M. esteraromaticum utiliza, frente al incremento de la temperatura, la estrategia es aumentar la longitud de sus ácidos grasos de cadenas ramificada impar (17 átomos de carbono con disminución de 15:0 anteiso, así como el porcentaje de ácidos grasos 15:0 iso (de mayor punto de fusión a partir del respectivo anteiso. El aumento de la salinidad modifica la composición de ácidos grasos siguiendo patrones diferentes según sea la temperatura de incubación. A 14 y 28 °C incrementa los 15:0 iso y 17:0 iso en detrimento de sus homólogos anteiso. A 37 °C este grupo de ácidos grasos no sigue los mismos patrones anteriores. La longitud de cadena, expresada como el índice C15/C17, es errática con el aumento de la salinidad.Microbacterium esteraromaticum is a microorganism that is frequently obtained of cultivations coming from landfarming or hydrocarbons biorremediation processes in the central Patagonia (Argentina and it is subjected to variations of temperature and changes of salinity that take place naturally. Its adaptability to these climatic conditions took us to study the changes of adaptation that take place in the fatty acids of its membranes. This work studied the combined effect of temperature and salt concentration on the membrane fatty acids composition of Microbacterium esteraromaticum GNP5

  7. A combination of omega-3 fatty acids, folic acid and B-group vitamins is superior at lowering homocysteine than omega-3 alone: A meta-analysis.

    Science.gov (United States)

    Dawson, Samantha Loren; Bowe, Steven John; Crowe, Timothy Charles

    2016-06-01

    The aim of the study was to assess whether omega-3 polyunsaturated fatty acid supplementation alone or in combination with folic acid and B-group vitamins is effective in lowering homocysteine. The Medline Ovid, Embase and Cochrane databases were searched for randomized-controlled trial studies that intervened with omega-3 supplementation (with or without folic acid) and measured changes in homocysteine concentration. Studies were pooled using a random effects model for meta-analysis. Three different models were analyzed: all trials combined, omega-3 polyunsaturated fatty acid trials, and omega-3 polyunsaturated fatty acids with folic acid and B-group vitamin trials. Nineteen studies were included, consisting of 3267 participants completing 21 trials. Studies were heterogeneous; varying by dose, duration and participant health conditions. Across all trials, omega-3 supplementation was effective in lowering homocysteine by an average of 1.18μmol/L (95%CI: (-1.89, -0.48), P=.001). The average homocysteine-lowering effect was greater when omega-3 supplementation was combined with folic acid and B-group vitamins (-1.37μmol/L, 95%CI: (-2.38, -0.36), Psupplementation alone (-1.09μmol/L 95%CI: (-2.04, -0.13), P=.03). Omega-3 polyunsaturated fatty acid supplementation was associated with a modest reduction in homocysteine. For the purposes of reducing homocysteine, a combination of omega-3s (0.2-6g/day), folic acid (150 - 2500μg/day) and vitamins B6 and B12 may be more effective than omega-3 supplementation alone. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Esteres metílicos de ácidos grasos como carburantes. Implicaciones económicas, ecológicas y energéticas

    Directory of Open Access Journals (Sweden)

    Gómez Herrera, Carlos

    1995-04-01

    Full Text Available Changes in the "Common Agricultural Policy" of the European Union have increased the rapeseed crops on "set-aside" lands remarkably. Rapeseed oils are transesterified with methanol to obtain fatty acid methyl esters. Blends of these esters with diesel oil are sold in petrol stations in different european countries like any other fuel.
    This informative article starts by reviewing basic characteristics of diesel fuel, and continues with an analysis of physical properties, chemical composition and present specifications for the rapeseed methyl esters. Subsequently several implications derived from the industrial development of this biofuel are discussed. These implications are economic (production, consumption, prices, subventions, tax exemptions, ecological (nearly zero emissions for whole cycle of carbon dioxide, other exhaust emissions from combustion, ecobalances, and energetic (complete evaluation of energy expenditure for production, energetic ratios.

    Los cambios en la "Common Agricultural Policy" de la Unión Europea han incrementado notablemente los cultivos de colza en los terrenos "setaside". El aceite de colza se transesterifica con metanol para obtener esteres metílicos de ácidos grasos del aceite de sus semillas. Mezclas de estos metilésteres con gasóleo se venden en gasolineras de diferentes países europeos como cualquier otro carburante.
    Este artículo de información comienza por una revisión de características básicas del gasóleo, seguida por un análisis de las propiedades físicas, la composición química y las especificaciones actuales de los metilésteres de colza. A continuación se discuten diversas implicaciones derivadas del desarrollo industrial de este biocombustible. Las mismas son económicas (producción, consumo, precios, subvenciones, exención de Impuestos, ecológicas (emisiones casi nulas para el ciclo completo del dióxido de carbono, otras emisiones procedentes de la combusti

  9. Transesterificación de ésteres grasos con arilaminoalcoholes. Síntesis de mono- y diacilderivados del 3-fenilamino-1,2-propanodiol

    Directory of Open Access Journals (Sweden)

    Gómez Gómez, R.

    1991-10-01

    Full Text Available In this paper the synthesis of acylderivatives of 3-phenylamino- 1,2 propanediol has been studied. These compounds are prepared by transesterification of fatty acids methyl esters with the amino-alcohol and sodium methoxide as catalyst. The reaction was carried out with mechanical stirring under vacuum. The effect of temperature, molar relation of reactives, time and concentration of catalyst on the reaction yield has been investigated. Yield increases with temperature and ester concentration until the optimun reaction temperature is reached. This temperature depend on molar relation ester/aminoalcohol (140 °C for 1/1 and 2/1 values and 120 °C for 4/1 value. The composition of reaction mixture was evaluated from the mono/di relation. This relation decrease when temperature and molar relation increase.

    En el presente trabajo se ha abordado la síntesis de los acilderivados del 3-fenilamino-1,2-propanodiol por transesterificación de ésteres metílicos de ácidos grasos con 3-fenilamino- 1,2-propanodiol utilizando metóxido sódico como catalizador. La reacción se lleva a cabo bajo presión reducida y agitación mecánica. Se ha estudiado la influencia de la temperatura, relación molar de los reactivos, tiempo y concentración de catalizador sobre el rendimiento de la reacción. El rendimiento aumenta con la temperatura y la concentración de éster hasta alcanzar la temperatura óptima de reacción. Esta temperatura depende de la relación molar y es de 140 °C para las relaciones molares éster: 3-fenilamino-1,2-propanodiol (1:1 y (2:1 y de 120 °C para (4:1. La composición de la mezcla de reacción se evalúa mediante la relación mono-/di-. Esta relación disminuye conforme aumenta la temperatura y la relación molar.

  10. Modelado de un reactor tubular de lipasas inmovilizadas para la producción de glicerol y ácidos grasos a partir de aceites

    Directory of Open Access Journals (Sweden)

    Oddone, Sebastián

    2010-06-01

    Full Text Available Advances in the design of a bioreactor in the fats and oils industry have permitted the hydrolysis of triglycerides in mild conditions and improved productivity while avoiding the formation of unwanted byproducts. The present work develops a mathematical model that describes the hydrolytic activity of a tubular reactor with immobilized lipases for the production of glycerol and fatty acids from the oil trade. Runge Kutta’s numerical method of high order has been applied, considering that there is no accumulation of the substratum in the surface of the membrane, where the enzyme is. At the same time, different equations based on the kinetic model of Michaelis Mentens and the Ping-Pong bi-bi mechanism were examined. Experimental data in discontinuous systems are the basis for the development of the quantitative mathematical model that was used to simulate the process computationally. The obtained results allow for optimizing both the operative variables and the economic aspects of industrial processes.

    Los avances en el diseño de biorreactores en la industria de grasas y aceites permiten realizar la hidrólisis de triglicéridos en condiciones suaves, mejorando la productividad y evitando la formación de subproductos indeseables. En el presente trabajo se desarrolla un modelo matemático que describe la actividad hidrolítica de un reactor tubular con lipasas inmovilizadas para la producción de ácidos grasos a partir de aceites comerciales. Se aplico el método numérico de Runge Kutta de alto orden, considerando que no hay acumulación de sustrato en la superficie de la membrana, donde se encuentra la enzima. Además se analizaron distintas ecuaciones de velocidad de reacción basadas en la cinética de Michaelis-Menten y en un mecanismo de ping-pong bi-bi. Los datos experimentales en sistemas discontinuos forman la base del desarrollo del modelo matemático, empleado para simular el proceso computacionalmente. Los resultados

  11. Estudio de la purificación de ácidos grasos, tocoferoles y esteroles a partir del destilado de desodorización.

    Directory of Open Access Journals (Sweden)

    Martinello, M. A.

    2005-09-01

    Full Text Available The operations to purify deodorizer distillates were studied in this investigation. The purification technology included esterification, two stages of molecular distillation and crystallization. Separation tests by molecular distillation with and without previous esterification of fatty acids were carried out. Esterification gave bigger separation efficiency in all first stage molecular distillation tests. The second stage of molecular distillation allowed increasing concentrations of tocopherols and sterols. Crystallization of the distillated final stream by the second stage of molecular distillation allowed the separation of more than 40 % of sterols, and gave a highly concentrated product (more than 92 % w/w of sterols. The final concentration of tocopherols in two treated samples of sunflower deodorizer distillate was 33.94 % and 20.60 % w/w respectively, and a sample from soy processing gave a value of 56.49 %.En esta investigación se han estudiado las operaciones para la purificación de los destilados de desodorización. La tecnología utilizada para la purificación incluyó esterificación, destilación molecular de dos etapas y cristalización. Se realizaron pruebas de separación por destilación molecular con y sin esterificación previa de los ácidos grasos libres. En todos los ensayos la esterificación condujo a una mayor eficiencia de separación en la primera etapa de destilación molecular. La segunda etapa de destilación molecular permitió aumentar la concentración de tocoferoles y esteroles. La cristalización de la corriente final de destilado (segunda etapa de destilación molecular permitió separar más del 40 % de los esteroles, en un producto altamente concentrado en los mismos (más de 92 % en peso. La concentración final en tocoferoles de dos muestras de destilado de desodorización de aceite de girasol ensayadas fue de 33,94 y 20,60 % respectivamente, y una muestra de destilado de desodorización de aceite de

  12. Suplementaci??n de la dieta de ovejas lecheras con aceite de girasol y l??pidos marinos para modificar la composici??n de la grasa de la leche: efecto sobre el rendimiento productivo de los animales, la microbiota y las caracter??sticas de la fermentaci??n ruminal y el perfil de ??cidos grasos de la leche y la digesta

    OpenAIRE

    Guti??rrez Toral, Pablo

    2011-01-01

    214 p. Se han realizado cinco experimentos con ovejas, con el objetivo de investigar el efecto de la suplementaci??n con aceite de girasol y, o bien aceite de pescado, o bien microalgas marinas, sobre la composici??n de los ??cidos grasos de la leche y la digesta, la micriobiota, la fermantaci??n ruminal y el rendimiento productivo de los animales

  13. EMBOLISMO GRASO EN UN NIÑO CON DISTROFIA MUSCULAR DE DUCHENNE Y FRACTURA BILATERAL DE FÉMUR. UNA RARA ASOCIACIÓN. Fat embolism syndrome in a child with muscular dystrophy of Duchenne type bilateral femur fracture. A rare association.

    Directory of Open Access Journals (Sweden)

    Enrique Vergara Amador

    2007-03-01

    Full Text Available Las fracturas de fémur en pacientes que sufren de distrofia muscular de Duchenne (DMD son frecuentes, con una incidencia entre 15-44 por ciento. El embolismo graso se presenta en fracturas de huesos largos generalmente asociado a trauma de alta energía o a lesiones extensas de tejidos blandos. El diagnóstico de embolismo graso no es tan frecuente en niños posiblemente porque cursa con presentaciones subclínicas. No existen reportes de embolismo graso asociado a distrofia muscular de Duchenne. Informamos el caso de un niño con distrofia muscular Duchenne que sufrió fractura bilateral de fémur y embolismo graso.It is high the frequency of femur fracture in children with Duchenne Muscular Dystrophy (DMD, with an incidence between 15 and 44%. The fatty embolism is presented in fractures of long bones generally associated to trauma of high energy or to extensive lesions of soft tissues. The diagnosis is not frequent in children probably because they can be presentations subclínicas. We could not find reports of fatty embolism associated to Duchenne muscular dystrophy. We present the case of a boy with Duchenne muscular dystrophy that suffered bilateral fracture of femur and fatty embolism.

  14. Low omega-3 index in pregnancy is a possible biological risk factor for postpartum depression.

    Science.gov (United States)

    Markhus, Maria Wik; Skotheim, Siv; Graff, Ingvild Eide; Frøyland, Livar; Braarud, Hanne Cecilie; Stormark, Kjell Morten; Malde, Marian Kjellevold

    2013-01-01

    Depression is a common disorder affecting 10-15% women in the postpartum period. Postpartum depression can disrupt early mother-infant interaction, and constitutes a risk factor for early child development. Recently, attention has been drawn to the hypothesis that a low intake of seafood in pregnancy can be a risk factor for postpartum depression. Seafood is a unique dietary source of the marine omega-3 fatty acids and is a natural part of a healthy balanced diet that is especially important during pregnancy. In a community based prospective cohort in a municipality in Western Norway, we investigated both nutritional and psychological risk factors for postpartum depression. The source population was all women who were pregnant within the period November 2009 - June 2011. The fatty acid status in red blood cells was assessed in the 28(th) gestation week and participants were screened for postpartum depression using the Edinburgh Postnatal Depression Scale (EPDS) three months after delivery. The aim of the present study was to investigate if a low omega-3 index in pregnancy is a possible risk factor for postpartum depression. In a simple regression model, the omega-3 index was associated with the EPDS score in a nonlinear inverse manner with an R square of 19. Thus, the low omega-3 index explained 19% of the variance in the EPDS score. The DPA content, DHA content, omega-3 index, omega-3/omega-6 ratio, total HUFA score, and the omega-3 HUFA score were all inversely correlated with the EPDS score. The EPDS scores of participants in the lowest omega-3 index quartile were significantly different to the three other omega-3 index quartiles. In this study population, a low omega-3 index in late pregnancy was associated with higher depression score three months postpartum.

  15. Low omega-3 index in pregnancy is a possible biological risk factor for postpartum depression.

    Directory of Open Access Journals (Sweden)

    Maria Wik Markhus

    Full Text Available Depression is a common disorder affecting 10-15% women in the postpartum period. Postpartum depression can disrupt early mother-infant interaction, and constitutes a risk factor for early child development. Recently, attention has been drawn to the hypothesis that a low intake of seafood in pregnancy can be a risk factor for postpartum depression. Seafood is a unique dietary source of the marine omega-3 fatty acids and is a natural part of a healthy balanced diet that is especially important during pregnancy.In a community based prospective cohort in a municipality in Western Norway, we investigated both nutritional and psychological risk factors for postpartum depression. The source population was all women who were pregnant within the period November 2009 - June 2011. The fatty acid status in red blood cells was assessed in the 28(th gestation week and participants were screened for postpartum depression using the Edinburgh Postnatal Depression Scale (EPDS three months after delivery. The aim of the present study was to investigate if a low omega-3 index in pregnancy is a possible risk factor for postpartum depression.In a simple regression model, the omega-3 index was associated with the EPDS score in a nonlinear inverse manner with an R square of 19. Thus, the low omega-3 index explained 19% of the variance in the EPDS score. The DPA content, DHA content, omega-3 index, omega-3/omega-6 ratio, total HUFA score, and the omega-3 HUFA score were all inversely correlated with the EPDS score. The EPDS scores of participants in the lowest omega-3 index quartile were significantly different to the three other omega-3 index quartiles.In this study population, a low omega-3 index in late pregnancy was associated with higher depression score three months postpartum.

  16. Development of omega-3 rich energy bar with flaxseed.

    Science.gov (United States)

    Mridula, D; Singh, K K; Barnwal, P

    2013-10-01

    Energy bar sample were prepared with different levels of flaxseed (0-20%) in addition to cereals and pulses with varying levels of sweeteners (45, 50, and 55%) to deliver a nutritious food to the consumer. The developed bars were evaluated for textural, colour, nutritional quality, sensory attributes and total microbial load. Different levels of flaxseed and sweeteners significantly affected the hue and chroma values of the energy bar. In general the level of flaxseed in energy bar did not affect the hardness but it was decreased with increasing level of sweeteners except in control sample. The total calories obtained from the energy bar showed significant increase with the increasing levels of flaxseed, the maximum (397.95 kcal) being for bars with 20% flaxseed and 45% sweeteners. This energy bar sample also showed the maximum protein (12.41%), crude fat (11.86%), ash (1.65%), iron (3.77 mg/100 g), crude fiber (2.18%) and omega-3 as alpha-linolenic acid (22.50%, fatty acid basis) content. The overall mean sensory score for overall acceptability for samples with 10% flaxseed and 55% sweeteners and 15% flaxseed and 45% sweeteners were at par but the omega-3 and other nutrients in the later sample was higher than the former sample, hence, 15% flaxseed and 45% sweeteners along with other ingredients may be considered for production of acceptable quality omega-3 fatty acid rich energy bar at commercial scale, which also stored well at refrigerated condition.

  17. Final Report: Posttest Analysis of Omega II Optical Specimens

    Energy Technology Data Exchange (ETDEWEB)

    Newlander, C D; Fisher, J H

    2007-01-30

    Preliminary posttest analyses have been completed on optical specimens exposed during the Omega II test series conducted on 14 July 2006. The Omega Facility, located at the Laboratory for Laser Energetics (LLE) at the University of Rochester was used to produce X-ray environments through the interaction of intense pulsed laser radiation upon germanium-loaded silica aerogels. The optical specimen testing was supported by GH Systems through experiment design, pre- and post-test analyses, specimen acquisition, and overall technical experience. The test specimens were fabricated and characterized by Surface Optics Corporation (SOC), San Diego, CA and were simple protected gold coatings on silica substrates. Six test specimens were exposed, five filtered with thin beryllium foil filters, and one unfiltered which was exposed directly to the raw environment. The experimental objectives were: (1) demonstrate that tests of optical specimens could be performed at the Omega facility; (2) evaluate the use and survivability of beryllium foil filters as a function of thickness; (3) obtain damage data on optical specimens which ranged from no damage to damage; (4) correlate existing thermal response models with the damage data; (5) evaluate the use of the direct raw environment upon the specimen response and the ability/desirability to conduct sensitive optical specimen tests using the raw environment; and (6) initiate the development of a protocol for performing optical coatings/mirror tests. This report documents the activities performed by GH Systems in evaluating and using the environments provided by LLNL, the PUFFTFT analyses performed using those environments, and the calculated results compared to the observed and measured posttest data.

  18. The NIF x-ray spectrometer calibration campaign at Omega.

    Science.gov (United States)

    Pérez, F; Kemp, G E; Regan, S P; Barrios, M A; Pino, J; Scott, H; Ayers, S; Chen, H; Emig, J; Colvin, J D; Bedzyk, M; Shoup, M J; Agliata, A; Yaakobi, B; Marshall, F J; Hamilton, R A; Jaquez, J; Farrell, M; Nikroo, A; Fournier, K B

    2014-11-01

    The calibration campaign of the National Ignition Facility X-ray Spectrometer (NXS) was carried out at the Omega laser facility. Spherically symmetric, laser-driven, millimeter-scale x-ray sources of K-shell and L-shell emission from various mid-Z elements were designed for the 2-18 keV energy range of the NXS. The absolute spectral brightness was measured by two calibrated spectrometers. We compare the measured performance of the target design to radiation hydrodynamics simulations.

  19. Superconducting magnet coils for the 'Omega' spark chamber at CERN

    CERN Document Server

    Schleich, A

    1972-01-01

    Superconducting windings of zero electrical resistance are being carried over from the development stage into industrial application. Brown Boveri are building the superconducting d.c. excitation system for the 'Omega' magnet which will be used for nuclear physics research at CERN. The magnet will weigh 1300 t and its excitation coils will have an overall diameter of 5 m. Magnet, coils and type of conductor are described. Special requirements and design features of the electrical insulation, thermal insulation, and mechanical support system for the windings operating under high vacuum at -269 degrees C are discussed. (15 refs).

  20. New natural antioxidants for protecting omega-3 rich products

    DEFF Research Database (Denmark)

    Farvin, Sabeena; Jacobsen, Charlotte

    2012-01-01

    The long-chain (LC) highly unsaturated omega-3 fatty acids, EPA (eicosapentaenoic acid, 20:5) and DHA (docosahexaenoic acid, 22:6) are vital for a wide range of biological functions and are implicated in the prevention of numerous diseases. However, these fatty acids are highly susceptible...... antioxidants from yoghurt, potato peel, fish protein hydrolysates and seaweed, which were able to protect highly unsaturated fish oil from oxidation. These antioxidant extracts may have potential for commercial exploitation. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim....

  1. Radiative shocks in gas on the Omega laser

    Science.gov (United States)

    Reighard, A.; Drake, R. P.; Keiter, P.; Korreck, K. E.; Perry, T. S.; Robey, H. A.; Remington, B. A.; Wallace, R. J.; Ryutov, D. D.; Knauer, J.; Calder, A.; Rosner, R.; Fryxell, B.; Arnett, D.; Turner, N.; Stone, J.; Koenig, M.; Bouquet, Serge

    2002-11-01

    A number of astrophysical systems involve radiative shocks that collapse spatially in response to the energy lost through radiation. This is believed to produce thin, dense, unstable shells. We have begun experiments on the Omega laser intended to produce such collapsing shocks and to study their evolution. The experiments use the laser to accelerate a thin slab of Be, which becomes a piston that drives a shock through 1.1 atm of Ar gas at 100 km/s. The shock is predicted to collapse. Experiments are in preparation that will detect the dense layer and also the radiative precursor in front of the shock. We will report their results.

  2. The mothers, Omega-3 and mental health study

    Directory of Open Access Journals (Sweden)

    Vazquez Delia

    2011-06-01

    Full Text Available Abstract Background Major depressive disorder (MDD during pregnancy and postpartum depression are associated with significant maternal and neonatal morbidity. While antidepressants are readily used in pregnancy, studies have raised concerns regarding neurobehavioral outcomes in exposed infants. Omega-3 fatty acid supplementation, most frequently from fish oil, has emerged as a possible treatment or prevention strategy for MDD in non-pregnant individuals, and may have beneficial effects in pregnant women. Although published observational studies in the psychiatric literature suggest that maternal docosahexaenoic acid (DHA deficiency may lead to the development of MDD in pregnancy and postpartum, there are more intervention trials suggesting clinical benefit for supplementation with eicosapentaenoic acid (EPA in MDD. Methods/Design The Mothers, Omega-3 and Mental Health study is a double blind, placebo-controlled, randomized controlled trial to assess whether omega-3 fatty acid supplementation may prevent antenatal and postpartum depressive symptoms among pregnant women at risk for depression. We plan to recruit 126 pregnant women at less than 20 weeks gestation from prenatal clinics at two health systems in Ann Arbor, Michigan and the surrounding communities. We will follow them prospectively over the course of their pregnancies and up to 6 weeks postpartum. Enrolled participants will be randomized to one of three groups: a EPA-rich fish oil supplement (1060 mg EPA plus 274 mg DHA b DHA-rich fish oil supplement (900 mg DHA plus 180 mg EPA; or c a placebo. The primary outcome for this study is the Beck Depression Inventory (BDI score at 6 weeks postpartum. We will need to randomize 126 women to have 80% power to detect a 50% reduction in participants' mean BDI scores with EPA or DHA supplementation compared with placebo. We will also gather information on secondary outcome measures which will include: omega-3 fatty acid concentrations in maternal

  3. Absorption of the omega and phi Mesons in Nuclei

    Energy Technology Data Exchange (ETDEWEB)

    M. H. Wood, R. Nasseripour, M. Paolone, C. Djalali, D. P. Weygand, the CLAS Collaboration

    2010-09-01

    Due to their long lifetimes, the $\\omega$ and $\\phi$ mesons are the ideal candidates for the study of possible modifications of the in-medium meson-nucleon interaction through their absorption inside the nucleus. During the E01-112 experiment at the Thomas Jefferson National Accelerator Facility, the mesons were photoproduced from $^{2}$H, C, Ti, Fe, and Pb targets. This paper reports the first measurement of the ratio of nuclear transparencies for the $e^{+}e^{-}$ channel. The ratios indicate larger in-medium widths compared with what have been reported in other reaction channels.

  4. Perfil de lípidos y ácidos grasos de Perna viridis, mejillón verde (Mollusca: Bivalvia en el oriente venezolano y la costa oeste de Trinidad

    Directory of Open Access Journals (Sweden)

    Tamar Koftayan

    2011-03-01

    Full Text Available Los lípidos totales fueron extraídos, identificados y cuantificados por gravimetría, mediante TLC/FID (sistema Iatroscan. Los ácidos grasos de los lípidos totales, fosfolípidos y triacilgliceroles fueron identificados y cuantificados por cromatografía de gases. Las mayores concentraciones de lípidos totales se presentaron en las muestras de Los Cedros, La Brea y Chaguaramas con valores de 7.92, 7.74 y 7.53%; respectivamente y los valores mínimos en las de La Restinga (6.08%. En la composición lípidica, las muestras de Chacopata presentaron la menor concentración de fosfolípidos (48.86% y los máximos valores de colesterol (38.87% y triacilgliceroles (12.26%, y las muestras de La Esmeralda y Río Caribe exhibieron concentraciones máximas de fosfolípidos (88.71-84.93%, respectivamente y mínimas de colesterol (6.50-4.42%. En los lípidos totales, los ácidos grasos saturados se encontraron entre 15.04 y 65.55%, con máximos en muestras de La Esmeralda y mínimos en Chacopata y los poliinsaturados estuvieron entre 7.80 y 37.18%, con máximos valores en la Brea y mínimos en la Esmeralda. En los fosfolípidos, la concentración de ácidos grasos saturados estuvo entre 38.81 y 48.68% para las muestras de Chaguaramas y Chacopata, respectivamente; los ácidos grasos poliinsaturados se encontraron entre no detectado y 34.51%, con altas concentraciones en muestras de Los Cedros (27.97% y Chaguaramas (34.51%. En los triacilgliceroles, la composición de ácidos grasos saturados variaron entre 14.27 y 53.80%, con baja concentración en Chacopata y alta concentración en La Restinga; los ácidos grasos poliinsaturados estuvieron entre 4.66 y 35.55%, con valores menores en las muestras de Chacopata (4.66% y mayores en Chaguaramas. El consumo frecuente de Perna viridis es recomendable, debido a su alto contenido de fosfolípidos y ácidos grasos insaturados.Lipid and fatty acid profile of Perna viridis, Green Mussel (Mollusca: Bivalvia in

  5. Omega-3 Fatty Acids for Autistic Spectrum Disorder: A Systematic Review

    Science.gov (United States)

    Bent, Stephen; Bertoglio, Kiah; Hendren, Robert L.

    2009-01-01

    We conducted a systematic review to determine the safety and efficacy of omega-3 fatty acids for autistic spectrum disorder (ASD). Articles were identified by a search of MEDLINE, EMBASE, and the Cochrane Database using the terms autism or autistic and omega-3 fatty acids. The search identified 143 potential articles and six satisfied all…

  6. Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work?

    NARCIS (Netherlands)

    Kromhout, D.; Yasuda, S.; Geleijnse, J.M.; Shimokawa, H.

    2012-01-01

    Omega-3 fatty acids, which are found abundantly in fish oil, exert pleiotropic cardiometabolic effects with a diverse range of actions. The results of previous studies raised a lot of interest in the role of fish oil and omega-3 fatty acids in primary and secondary prevention of cardiovascular

  7. Omega-3: a link between global climate change and human health.

    Science.gov (United States)

    Kang, Jing X

    2011-01-01

    In recent years, global climate change has been shown to detrimentally affect many biological and environmental factors, including those of marine ecosystems. In particular, global climate change has been linked to an increase in atmospheric carbon dioxide, UV irradiation, and ocean temperatures, resulting in decreased marine phytoplankton growth and reduced synthesis of omega-3 polyunsaturated fatty acids (PUFAs). Marine phytoplankton are the primary producers of omega-3 PUFAs, which are essential nutrients for normal human growth and development and have many beneficial effects on human health. Thus, these detrimental effects of climate change on the oceans may reduce the availability of omega-3 PUFAs in our diets, exacerbating the modern deficiency of omega-3 PUFAs and imbalance of the tissue omega-6/omega-3 PUFA ratio, which have been associated with an increased risk for cardiovascular disease, cancer, diabetes, and neurodegenerative disease. This article provides new insight into the relationship between global climate change and human health by identifying omega-3 PUFA availability as a potentially important link, and proposes a biotechnological strategy for addressing the potential shortage of omega-3 PUFAs in human diets resulting from global climate change. Copyright © 2011 Elsevier Inc. All rights reserved.

  8. Positive association between blood Omega-3 index and cognition in healthy Dutch adolescents

    NARCIS (Netherlands)

    Van der Wurff, Inge; Von Schacky, Clemens; Berge, Kjetil; Zeegers, Maurice P; Kirschner, Paul A.; De Groot, Renate

    2016-01-01

    The impact of omega-3 long-chain polyunsaturated fatty acids (LCPUFAs) on cognition is heavily debated. In the current study, the possible association between omega-3 LCPUFAs in blood and cognitive performance of 266 typically developing adolescents aged 13–15 years is investigated. Baseline data

  9. Association between Blood Omega-3 Index and Cognition in Typically Developing Dutch Adolescents

    NARCIS (Netherlands)

    Van der Wurff, Inge; Von Schacke, Clemens; Berge, Kjetil; Zeegers, Maurice; Kirschner, Paul A.; De Groot, Renate

    2017-01-01

    The impact of omega-3 long-chain polyunsaturated fatty acids (LCPUFAs) on cognition is heavily debated. In the current study, the possible association between omega-3 LCPUFAs in blood and cognitive performance of 266 typically developing adolescents aged 13–15 years is investigated. Baseline data

  10. Omega-3 free fatty acids for the treatment of severe hypertriglyceridemia

    DEFF Research Database (Denmark)

    Kastelein, John J P; Maki, Kevin C; Susekov, Andrey

    2014-01-01

    Omega-3 fatty acids in free fatty acid form have enhanced bioavailability, and plasma levels are less influenced by food than for ethyl ester forms.......Omega-3 fatty acids in free fatty acid form have enhanced bioavailability, and plasma levels are less influenced by food than for ethyl ester forms....

  11. Monitoring the photometric behavior of OmegaCAM with Astro-WISE

    NARCIS (Netherlands)

    Verdoes Kleijn, G. A.; Kuijken, K. H.; Valentijn, E. A.; Boxhoorn, D. R.; Begeman, K. G.; Deul, E. R.; Helmich, E. M.; Rengelink, R.

    The OmegaCAM wide-field optical imager is the sole instrument on the VLT Survey Telescope at ESO's Paranal Observatory. The instrument, as well as the telescope, have been designed for surveys with very good, natural seeing-limited image quality over a 1 square degree field. OmegaCAM was

  12. The effects of addition of omega-3, 6, 9 fatty acids on the quality of ...

    African Journals Online (AJOL)

    This study was aimed to investigate the effects of omega-3, 6, 9 fatty acids on the characteristics of bovine chilled and frozen-thawed semen. For this purpose, oil containing different levels of omega-3, 6, 9 fatty acids were added to semen extender. To emulsify the oil in semen extender, polyethylene glycol (PEG) was added ...

  13. Functional beverage products using caseinate–omega-3 oil-oat beta glucan emulsions

    Science.gov (United States)

    Beverages with soluble dietary fiber and Omega 3 oil are highly desired by health conscious consumers. However, Omega 3 oil is prone to oxidation and accompanying deterioration of sensory profiles; there is an issue to incorporate soluble fiber into beverage products that will not interfere with oxi...

  14. Omega-3 fatty acid supplementation decreases matrix metalloproteinase-9 production in relapsing-remitting multiple sclerosis

    Science.gov (United States)

    Shinto, L.; Marracci, G.; Baldauf-Wagner, S.; Strehlow, A.; Yadav, V.; Stuber, L.; Bourdette, D.

    2009-01-01

    Objectives The primary objective was to evaluate the effect of omega-3 fatty acids (omega-3 FA) on matrix metalloproteinase-9 (MMP-9) production by immune cells in multiple sclerosis (MS). Quality of life, fatty acid levels, and safety were also evaluated. Materials and Methods Ten participants with relapsing-remitting MS (RRMS) received omega-3 FA supplementation (9.6 grams/day fish oil) in an open-label study. Participants were evaluated at four time points, baseline, after 1-month of omega-3 FA supplementation, after 3-months of omega-3 FA supplementation, and after a 3-month wash out. Results Immune cell secretion of MMP-9 decreased by 58% after 3-months of omega-3 FA supplementation when compared to baseline levels (p < 0.01). This effect was coupled with a significant increase in omega-3 FA levels in red blood cell membranes. Conclusions Omega-3 FA significantly decreased MMP-9 levels in RRMS and may act as immune-modulator that has potential therapeutic benefit in MS patients. PMID:19171471

  15. Insulin-like growth factors (IGFs) and IGF binding proteins in active Crohn's disease treated with omega-3 or omega-6 fatty acids and corticosteroids

    DEFF Research Database (Denmark)

    Eivindson, Martin; Grønbaek, Henning; Nielsen, Jens Nederby

    2005-01-01

    of the present study was to examine the effects of enteral nutrition, Impact Powder, as adjuvant therapy to corticosteroid treatment on changes in the GH/IGF-I axis in patients with Crohn's disease (CD). MATERIAL AND METHODS: The patients were randomized to 3-IP (omega-3-fatty acid (FA), 3 g/day) or 6-IP (omega...... with previously published studies and may be explained by corticosteroid treatment; however, we cannot exclude an additional effect of omega3-/omega6 FA as adjuvant enteral nutrition.......-6-FA, 9 g/day). Changes in total IGF-I (tIGF-I) and total IGF-II (tIGF-II), free IGF-I (fIGF-I), IGF binding proteins (IGFBP-1 and IGFBP-3), IGFBP-3 protease activity and insulin levels were examined in 31 patients with active CD (CDAI: 186-603) during treatment with prednisolone (40 mg for 1 week...

  16. Beneficial Effects of Omega-3 Polyunsaturated Fatty Acids in Gestational Diabetes: Consequences in Macrosomia and Adulthood Obesity

    OpenAIRE

    Yessoufou, Akadiri; Nekoua, Magloire P.; Gbankoto, Adam; Mashalla, Yohana; Moutairou, Kabirou

    2015-01-01

    Omega-3 polyunsaturated fatty acids (PUFAs) are increasingly being used to prevent cardiovascular diseases, including diabetes and obesity. In this paper, we report data on the observed effects of omega-3 PUFA on major metabolic disorders and immune system disruption during gestational diabetes and their consequences on macrosomia. While controversies still exist about omega-3 PUFA effects on antioxidant status regarding the level of omega-3 PUFA in diet supplementation, their lipid-lowering ...

  17. Effects of the omega-6:omega-3 fatty acid ratio of fat emulsions on the fatty acid composition in cell membranes and the anti-inflammatory action.

    Science.gov (United States)

    Hagi, Akifumi; Nakayama, Mitsuo; Shinzaki, Wataru; Haji, Seiji; Ohyanagi, Harumasa

    2010-01-01

    This study investigated the effects of parenterally administered fish oil (FO) on the fatty acid composition in rats to determine the optimal omega-6:omega-3 polyunsaturated fatty acid (PUFA) ratio of fat emulsions to achieve an anti-inflammatory effect. Male Sprague-Dawley rats were infused a parenteral nutrition (PN) solution containing fat emulsions with different omega-6:omega-3 PUFA ratios. The fatty acid content of phospholipids in the membranes of splenocytes was analyzed by gas chromatography (experiment 1). In addition, the amounts of leukotriene (LT) B(4) and LTB(5) released from peritoneal polymorphonuclear leukocytes (PMNs) were measured by high-performance liquid chromatography (experiment 2). In experiment 1, after infusion of the fat emulsion containing FO, the omega-3 PUFA content in cell membranes rose to 70% of the peak value on day 1 and nearly reached a plateau on day 3. The highest ratio of eicosapentaenoic acid (EPA) to arachidonic acid (AA) was achieved by administering a PN solution with the smallest omega-6:omega-3 PUFA ratio. In experiment 2, a larger amount of LTB(5) was released from Ca-ionophore-stimulated PMNs taken from rats given a larger quantity of FO. The ratio of LTB(5):LTB(4) released from PMNs correlated positively with the EPA:AA ratio in the membranous phospholipid and in serum. The omega-3 PUFAs were readily incorporated into the cell membrane within 3 days of infusion with the fat emulsion. The EPA:AA ratio in membranous phospholipid in PMNs was positively correlated with the LTB(5):LTB(4) production ratio and was a good indicator of anti-inflammatory effects.

  18. Does Supplementation with Omega-3 PUFAs Add to the Prevention of Cardiovascular Disease?

    Science.gov (United States)

    Rizos, Evangelos C; Elisaf, Moses S

    2017-06-01

    Omega-3 fatty acids are increasingly used for the protection of cardiovascular disease. The main but not the sole mechanism of action is the reduction of triglyceride levels. In this review, we summarize the effect of omega-3 supplements on all-cause and cardiovascular mortality, myocardial infarction, and stroke from the relevant randomized controlled trials. Twenty-one randomized controlled trials assessed omega-3 supplementation on mortality and cardiovascular-related outcomes. From these studies, as well as from the relevant meta-analyses, we found that omega-3 supplements do not exert a consistent benefit for cardiovascular protection. There is uncertainty of a clear profit from omega-3 supplementation in cardiovascular disease.

  19. Encapsulation of vegetable oils as source of omega-3 fatty acids for enriched functional foods.

    Science.gov (United States)

    Ruiz Ruiz, Jorge Carlos; Ortiz Vazquez, Elizabeth De La Luz; Segura Campos, Maira Rubi

    2017-05-03

    Polyunsaturated omega-3 fatty acids (PUFAs), a functional component present in vegetable oils, are generally recognized as being beneficial to health. Omega-3 PUFAs are rich in double bonds and unsaturated in nature; this attribute makes them highly susceptible to lipid oxidation and unfit for incorporation into long shelf life foods. The microencapsulation of oils in a polymeric matrix (mainly polysaccharides) offers the possibility of controlled release of the lipophilic functional ingredient and can be useful for the supplementation of foods with PUFAs. The present paper provides a literature review of different vegetable sources of omega-3 fatty acids, the functional effects of omega-3 fatty acids, different microencapsulation methods that can possibly be used for the encapsulation of oils, the properties of vegetable oil microcapsules, the effect of encapsulation on oxidation stability and fatty acid composition of vegetable oils, and the incorporation of long-chain omega-3 polyunsaturated fatty acids in foods.

  20. Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work?

    Science.gov (United States)

    Kromhout, Daan; Yasuda, Satoshi; Geleijnse, Johanna M.; Shimokawa, Hiroaki

    2012-01-01

    Omega-3 fatty acids, which are found abundantly in fish oil, exert pleiotropic cardiometabolic effects with a diverse range of actions. The results of previous studies raised a lot of interest in the role of fish oil and omega-3 fatty acids in primary and secondary prevention of cardiovascular diseases. The present review will focus on the current clinical uses of omega-3 fatty acids and provide an update on their effects. Since recently published trials in patients with coronary artery diseases or post-myocardial infarction did not show an effect of omega-3 fatty acids on major cardiovascular endpoints, this review will examine the limitations of those data and suggest recommendations for the use of omega-3 fatty acids. PMID:21933782

  1. Omega-3 Fatty Acids and Primary and Secondary Prevention of Cardiovascular Disease.

    Science.gov (United States)

    Cao, Yong; Lu, Lei; Liang, Jun; Liu, Min; Li, Xianchi; Sun, RongRong; Zheng, Yi; Zhang, Peiying

    2015-05-01

    The prevalence of cardiovascular disease (CVD) is increasing dramatically especially in developing countries like India. CVD is a leading cause of morbidity and mortality. There has been a growing awareness of the role of nutrients in the prevention of CVD. One specific recommendation in the battle against CVD is the increased intake of omega-3 fatty acids, which are polyunsaturated fatty acids. Studies have reported inverse associations of CVD with dietary intake of omega-3 fatty acids, suggesting that omega-3 fatty acids supplementation might exert protective effects on CVD. They exert their cardioprotective effect through multiple mechanisms. Omega-3 fatty acid therapy has shown promise as a useful tool in the primary and secondary prevention of CVD. This review briefly summarizes the effects of omega-3 fatty acids in primary and secondary prevention of CVD.

  2. Measurements of the branching fractions of exclusive charmless B meson decays with eta(') or omega mesons.

    Science.gov (United States)

    Aubert, B; Boutigny, D; Gaillard, J M; Hicheur, A; Karyotakis, Y; Lees, J P; Robbe, P; Tisserand, V; Palano, A; Chen, G P; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Reinertsen, P L; Stugu, B; Abbott, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Clark, A R; Gill, M S; Gritsan, A; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kluth, S; Kolomensky, Y G; Kral, J F; LeClerc, C; Levi, M E; Liu, T; Lynch, G; Meyer, A B; Momayezi, M; Oddone, P J; Perazzo, A; Pripstein, M; Roe, N A; Romosan, A; Ronan, M T; Shelkov, V G; Telnov, A V; Wenzel, W A; Bright-Thomas, P G; Harrison, T J; Hawkes, C M; Knowles, D J; O'Neale, S W; Penny, R C; Watson, A T; Watson, N K; Deppermann, T; Goetzen, K; Koch, H; Krug, J; Kunze, M; Lewandowski, B; Peters, K; Schmuecker, H; Steinke, M; Andress, J C; Barlow, N R; Bhimji, W; Chevalier, N; Clark, P J; Cottingham, W N; De Groot, N; Dyce, N; Foster, B; McFall, J D; Wallom, D; Wilson, F F; Abe, K; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Jolly, S; McKemey, A K; Tinslay, J; Blinov, V E; Bukin, A D; Bukin, D A; Buzykaev, A R; Golubev, V B; Ivanchenko, V N; Korol, A A; Kravchenko, E A; Onuchin, A P; Salnikov, A A; Serednyakov, S I; Skovpen, Y I; Telnov, V I; Yushkov, A N; Best, D; Lankford, A J; Mandelkern, M; McMahon, S; Stoker, D P; Ahsan, A; Arisaka, K; Buchanan, C; Chun, S; Branson, J G; MacFarlane, D B; Prell, S; Rahatlou, S; Raven, G; Sharma, V; Campagnari, C; Dahmes, B; Hart, P A; Kuznetsova, N; Levy, S L; Long, O; Lu, A; Richman, J D; Verkerke, W; Witherell, M; Yellin, S; Beringer, J; Dorfan, D E; Eisner, A M; Frey, A; Grillo, A A; Grothe, M; Heusch, C A; Johnson, R P; Kroeger, W; Lockman, W S; Pulliam, T; Sadrozinski, H; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Turri, M; Walkowiak, W; Williams, D C; Wilson, M G; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Hitlin, D G; Metzler, S; Oyang, J; Porter, F C; Ryd, A; Samuel, A; Weaver, M; Yang, S; Zhu, R Y; Devmal, S; Geld, T L; Jayatilleke, S; Mancinelli, G; Meadows, B T; Sokoloff, M D; Barillari, T; Bloom, P; Dima, M O; Fahey, S; Ford, W T; Hall, T L; Johnson, D R; Nauenberg, U; Olivas, A; Park, H; Rankin, P; Roy, J; Sen, S; Smith, J G; van Hoek, W C; Wagner, D L; Blouw, J; Harton, J L; Krishnamurthy, M; Soffer, A; Toki, W H; Wilson, R J; Zhang, J; Brandt, T; Brose, J; Colberg, T; Dahlinger, G; Dickopp, M; Dubitzky, R S; Maly, E; Müller-Pfefferkorn, R; Otto, S; Schubert, K R; Schwierz, R; Spaan, B; Wilden, L; Behr, L; Bernard, D; Bonneaud, G R; Brochard, F; Cohen-Tanugi, J; Ferrag, S; Roussot, E; T'Jampens, S; Thiebaux, C; Vasileiadis, G; Verderi, M; Anjomshoaa, A; Bernet, R; Khan, A; Muheim, F; Playfer, S; Swain, J E; Falbo, M; Borean, C; Bozzi, C; Dittongo, S; Folegani, M; Piemontese, L; Treadwell, E; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Falciai, D; Finocchiaro, G; Patteri, P; Peruzzi, I M; Piccolo, M; Xie, Y; Zallo, A; Bagnasco, S; Buzzo, A; Contri, R; Crosetti, G; Fabbricatore, P; Farinon, S; Lo Vetere, M; Macri, M; Monge, M R; Musenich, R; Pallavicini, M; Parodi, R; Passaggio, S; Pastore, F C; Patrignani, C; Pia, M G; Priano, C; Robutti, E; Santroni, A; Morii, M; Bartoldus, R; Dignan, T; Hamilton, R; Mallik, U; Cochran, J; Crawley, H B; Fischer, P A; Lamsa, J; Meyer, W T; Rosenberg, E I; Benkebil, M; Grosdidier, G; Hast, C; Höcker, A; Lacker, H M; LePeltier, V; Lutz, A M; Plaszczynski, S; Schune, M H; Trincaz-Duvoid, S; Valassi, A; Wormser, G; Bionta, R M; Brigljević, V; Lange, D J; Mugge, M; Shi, X; van Bibber, K; Wenaus, T J; Wright, D M; Wuest, C R; Carroll, M; Fry, J R; Gabathuler, E; Gamet, R; George, M; Kay, M; Payne, D J; Sloane, R J; Touramanis, C; Aspinwall, M L; Bowerman, D A; Dauncey, P D; Egede, U; Eschrich, I; Gunawardane, N J; Nash, J A; Sanders, P; Smith, D; Azzopardi, D E; Back, J J; Dixon, P; Harrison, P F; Potter, R J; Shorthouse, H W; Strother, P; Vidal, P B; Williams, M I; Cowan, G; George, S; Green, M G; Kurup, A; Marker, C E; McGrath, P; McMahon, T R; Ricciardi, S; Salvatore, F; Scott, I; Vaitsas, G; Brown, D; Davis, C L; Allison, J; Barlow, R J; Boyd, J T; Forti, A C; Fullwood, J; Jackson, F; Lafferty, G D; Savvas, N; Simopoulos, E T; Weatherall, J H; Farbin, A; Jawahery, A; Lillard, V; Olsen, J; Roberts, D A; Schieck, J R; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Moore, T B; Staengle, H; Willocq, S; Brau, B; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Milek, M; Patel, P M; Trischuk, J; Lanni, F; Palombo, F; Bauer, J M; Booke, M; Cremaldi, L; Eschenburg, V; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Martin, J P; Nief, J Y; Seitz, R; Taras, P; Zacek, V; Nicholson, H; Sutton, C S; Cartaro, C; Cavallo, N; De Nardo, G; Fabozzi, F; Gatto, C; Lista, L; Paolucci, P; Piccolo, D; Sciacca, C; LoSecco, J M; Alsmiller, J R; Gabriel, T A; Handler, T; Brau, J; Frey, R; Iwasaki, M; Sinev, N B; Strom, D; Colecchia, F; Dal Corso, F; Dorigo, A; Galeazzi, F; Margoni, M; Michelon, G; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Torassa, E; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; De la Vaissière, C; Del Buono, L; Hamon, O; Le Diberder, F; Leruste, P; Lory, J; Roos, L; Stark, J; Versillé, S; Manfredi, P F; Re, V; Speziali, V; Frank, E D; Gladney, L; Guo, Q H; Panetta, J H; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Carpinelli, M; Forti, F; Giorgi, M A; Lusiani, A; Martinez-Vidal, F; Morganti, M; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Simi, G; Triggiani, G; Walsh, J; Haire, M; Judd, D; Paick, K; Turnbull, L; Wagoner, D E; Albert, J; Bula, C; Elmer, P; Lu, C; McDonald, K T; Miftakov, V; Schaffner, S F; Smith, A J; Tumanov, A; Varnes, E W; Cavoto, G; del Re, D; Faccini, R; Ferrarotto, F; Ferroni, F; Fratini, K; Lamanna, E; Leonardi, E; Mazzoni, M A; Morganti, S; Piredda, G; Safai Tehrani, F; Serra, M; Voena, C; Christ, S; Waldi, R; Adye, T; Franek, B; Geddes, N I; Gopal, G P; Xella, S M; Aleksan, R; De Domenico, G; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P F; Hamel de Monchenault, G; Kozanecki, W; Langer, M; London, G W; Mayer, B; Serfass, B; Vasseur, G; Yeche, C; Zito, M; Copty, N; Purohit, M V; Singh, H; Yumiceva, F X; Adam, I; Anthony, P L; Aston, D; Baird, K; Bloom, E; Boyarski, A M; Bulos, F; Calderini, G; Claus, R; Convery, M R; Coupal, D P; Coward, D H; Dorfan, J; Doser, M; Dunwoodie, W; Field, R C; Glanzman, T; Godfrey, G L; Gowdy, S J; Grosso, P; Himel, T; Huffner, M E; Innes, W R; Jessop, C P; Kelsey, M H; Kim, P; Kocain, M L; Langenegger, U; Leith, D W; Luitz, S; Luth, V; Lynch, H L; Marsiske, H; Menke, S; Messner, R; Moffeit, K C; Mount, R; Muller, D R; O'Grady, C P; Perl, M; Petrak, S; Quinn, H; Ratcliff, B N; Robertson, S H; Rochester, L S; Roodman, A; Schietinger, T; Schindler, R H; Schwiening, J; Serbo, V V; Snyder, A; Soha, A; Spanier, S M; Stelzer, J; Su, D; Sullivan, M K; Tanaka, H A; Va'vra, J; Wagner, S R; Weinstein, A J; Wisniewski, W J; Wright, D H; Young, C C; Burchat, P R; Cheng, C H; Kirkby, D; Meyer, T I; Roat, C; Henderson, R; Bugg, W; Cohn, H; Weidemann, A W; Izen, J M; Kitayama, I; Lou, X C; Turcotte, M; Bianchi, F; Bona, M; Di Girolamo, B; Gamba, D; Smol, A; Zanin, D; Lanceri, L; Pompili, A; Vaugnin, G; Panvini, R S; Brown, C M; De Silva, A; Kowalewski, R; Roney, J M; Band, H R; Charles, E; Dasu, S; Di Lodovico, F; Eichenbaum, A M; Hu, H; Johnson, J R; Liu, R; Nielsen, J; Pan, Y; Prepost, R; Scott, I J; Sekula, S J; von Wimmersperg-Toeller, J H; Wu, S L; Yu, Z; Zobernig, H; Kordich, T M; Neal, H

    2001-11-26

    We present the results of searches for B decays to charmless two-body final states containing eta(') or omega mesons, based on 20.7 fb(-1) of data collected with the BABAR detector. We find the branching fractions Beta(B(+)-->eta(')K(+)) = (70+/-8+/-5) x 10(-6), Beta(B(0)-->eta(')K(0)) = (42(+13)(-11) +/- 4) x 10(-6), and Beta(B(+)-->omega pi(+)) = (6.6(+2.1)(-1.8) +/- 0.7) x 10(-6), where the first error quoted is statistical and the second is systematic. We give measurements of four additional modes for which the 90% confidence level upper limits are Beta(B(+)-->eta(')pi(+)) omega K(+)) omega K(0)) omega pi(0)) < 3 x 10(-6).

  3. Study of the reaction $\\pi^{-} Be \\to \\omega \\pi^{-} \\pi^{0} Be$

    CERN Document Server

    IHEP. Protvino

    1998-01-01

    The results of patial wave analysis of the omega pi- pi0 system, produced in the reaction pi- Be --> pi+ 2pi- 2pi0 Be at beam momentum of 37 GeV are presented. An indication of the resonant type structure with mass near 1.74 GeV and JpMetha=0-0+ in the omega rho- system was found. The decay branching ratio of a2(1320)- to omega pi- pi0 was measured. A wave with JpMetha=2+1+ shows a broad bump at M near 1.7 GeV. The decays pi2(1670)- --> omega rho- and a4(2040)- --> omega rho- were observed for the first time. The bump in the b1(1235)pi wave with exotic quantum numbers Jpc=1-+ at M near 1.7 GeV was observed.

  4. Stability and Stabilization of Omega-3 Oils as such and in Selected Foods

    DEFF Research Database (Denmark)

    Jacobsen, Charlotte

    oxidation, which will lead to formation of undesirable fishy and rancid off-flavours. Such off-flavours can lead to consumer rejection of omega-3 enriched foods. Important issues to address in order to avoid lipid oxidation are 1) processing conditions and product composition, 2) omega-3 PUFA source...... and delivery system, and 3) addition of antioxidants. This presentation will summarize our current knowledge about these issues in a range of different omega-3 enriched foods.......The application of omega-3 polyunsaturated fatty acids (PUFA) in foods has increased dramatically during the last decade due to the increasing awareness about the health beneficial effects of these fatty acids. Due to their polyunsaturated nature omega-3 PUFA are highly susceptible to lipid...

  5. Effects of microencapsulation on bioavailability of fish oil omega-3 fatty acids

    DEFF Research Database (Denmark)

    Christophersen, Philip Carsten B; Yang, Mingshi; Mu, Huiling

    2016-01-01

    Increased research interest in the health benefits of fish oils and the wide publicity of these studies have led to the marketing and launch of a wide array of new and traditional food and beverage products enriched with omega-3 fatty acids. This chapter focuses on the impact of microencapsulation...... stability by preventing oxidation and ensuring satisfactory organoleptic properties. Even though encapsulation excipients food matrices and lipid structures can affect the absorption rate of omega-3 fatty acids in short-term studies, microencapsulated fish oil and omega-3 fatty acids enriched foods...... and other factors on the bioavailability of omega-3 fatty acids from fish oils. To help understand the impact of microencapsulation on bioavailability of omega-3 fatty acids, it presents a brief overview of encapsulation techniques and excipients used. Microencapsulation of fish oil improves its chemical...

  6. Enrichment of foods with omega-3 fatty acids: A multidisciplinary challenge

    DEFF Research Database (Denmark)

    Jacobsen, Charlotte

    2010-01-01

    Enrichment of foods with marine omega-3 polyunsaturated fatty acids (PUFA) poses a multidisciplinary challenge to food industry and academia. Although our knowledge about possible health effects of omega-3 PUFA has increased tremendously during the last 30 years, there is still a lot to be learned...... about these healthy fatty acids. Moreover, consumer acceptance and lipid oxidation of omega-3 PUFA-enriched food are other major challenges that the food industry meet when developing omega-3-enriched foods. Two examples on multidisciplinary research projects to overcome some of these challenges...... are given in this article together with cases studies illustrating how lipid oxidation can be prevented in a range of different omega-3-enriched foods....

  7. LHCb: Measurement of the $\\Lambda_b^0$, $\\Xi_b^-$ and $\\Omega_b^-$ baryon masses

    CERN Multimedia

    Märki, R

    2013-01-01

    Mass measurements of $\\Lambda_b^0$, $\\Xi_b^-$ and $\\Omega_b^-$ at LHCb using 1~fb$^{-1}$ of data collected in 2011, reconstructing $\\Lambda_b^0 \\rightarrow J/\\psi \\Lambda$, $\\Xi_b^- \\rightarrow J/\\psi \\Xi^-$ and $\\Omega_b^- \\rightarrow J/\\psi \\Omega^-$.

  8. Conversion efficiency of alpha linolenic acid to omega-3 highly unsaturated fatty acids in aerial insectivore chicks.

    Science.gov (United States)

    Twining, Cornelia W; Lawrence, Peter; Winkler, David W; Flecker, Alexander S; Brenna, J Thomas

    2017-12-07

    Food availability and quality are both critical for growing young animals. In nature, swallows (Tachycineta bicolor) and other aerial insectivores feed on both aquatic insects, which are rich in omega-3 highly unsaturated fatty acids (HUFA) and terrestrial insects, which contain considerably lower amounts of omega-3 HUFA. Carnivorous mammals and fishes must obtain omega-3 HUFA from diet, as they have lost the capacity to convert the precursor omega-3 ALA into omega-3 HUFA. Thus, the relative value of aquatic versus terrestrial insects depends not only on the fatty acid composition of the prey, but also upon the capacity of consumers to convert ALA into omega-3 HUFA. We used a combination of stable-isotope-labeled fatty acid tracers to ask if, and how efficiently, Tree Swallows can deposit newly synthesized omega-3 HUFA into tissue. Our data show for the first time that Tree Swallows can convert ALA into omega-3 HUFA deposited in liver and skeletal muscle. However, high Tree Swallow demand for omega-3 HUFA combined with low ALA availability in natural terrestrial foods may strain their modest conversion ability. This suggests that while Tree Swallows can synthesize omega-3 HUFA de novo, omega-3 HUFA are ecologically essential nutrients in natural systems. Our findings thus provide mechanistic support for our previous findings and the importance of omega-3 HUFA -rich aquatic insects for Tree Swallows and most likely other aerial insectivores with similar niches. © 2017. Published by The Company of Biologists Ltd.

  9. Predicción del número de cetano de biocombustibles a partir de su composición de ácidos grasos//Cetane number estimation of biofuels from their fatty acid composition

    Directory of Open Access Journals (Sweden)

    Yisel Sánchez-Borroto

    2012-05-01

    Full Text Available El número de cetano (CN es una de las propiedades más importantes para evaluar la calidad del proceso de combustión de un combustible tipo diesel. El CN de biocombustibles derivados de aceites vegetales está influenciado por su composición de ácidos grasos. El objetivo de esta investigación es obtener dos modelos físico-matemáticos que establezcan una relación entre el número de cetano de biocombustibles derivados de aceites vegetales y su composición de ácidos grasos esenciales. Para predecir el CN se desarrollaron dos modelos mediante un análisis de regresión múltiple, basado en datos experimentales extraídos de bases de datos referenciadas. El ajuste de los coeficientes del modelo se basa en la obtención de residuales mínimos. Se realiza una validación parcial del modelo y se establecen las pautas para la validación total del mismo. A partir de estos resultados queda establecida una herramienta muy útil para la determinación del número de cetano. Palabras claves: número de cetano, biodiesel, aceites vegetales, ácidos grasos.______________________________________________________________________________ Abstract The cetane number is one of the main properties for characterization of the ignition quality of a fuel for its use in a diesel engine. The cetane number of biofuels obtained from different vegetable oils is strongly considerably by their fatty acid composition. The scope of this research is to obtain two physical-mathematical models that establish a relationship between the cetane number and the composition of different biofuels derived from vegetable oils. The models were developed using an analysis of multiple regression, based on experimental data available in the literature. The coefficients adjustment of the model was based on the obtaining of lower residual in the capacity of prediction of the model. A partial validation of the model was developed.  Starting from these results it a very useful tool for

  10. ACTIVIDAD ANTIOXIDANTE Y PERFIL DE ÁCIDOS GRASOS DE LAS SEMILLAS DE JABUTICABA (Myrciaria cauliflora BERG Antioxidant Activity and Profile Fatty Acids of Jabuticaba Seeds (Myrciaria cauliflora Berg

    Directory of Open Access Journals (Sweden)

    JORGE NEUZA

    2011-08-01

    Full Text Available Múltiples compuestos naturales encontrados en frutas, cereales y vegetales presentan actividad antioxidante. Este trabajo tuvo como objetivo caracterizar las semillas de jabuticaba (Myrciaria cauliflora Berg en cuanto a su composición proximal y potencial antioxidante, y evaluar el perfil de ácidos grasos en el aceite extraído de las mismas. Para la obtención del extracto, las semillas deshidratadas y trituradas fueron extraídas con alcohol etílico por 30 minutos, en la proporción de 1:3 de semillas:alcohol etílico, bajo agitación continua, a temperatura ambiente. Seguidamente, la mezcla fue filtrada y el sobrenadante deshidratado a 40 ºC con la finalidad de determinar, por pesaje directo, rendimiento en materia seca del extracto. De acuerdo con los resultados obtenidos, las semillas de jabuticaba mostraron ser fuente de carbohidratos totales importante, además presentaron actividad antioxidante relevante. El aceite de jabuticaba presentó porcentaje significativo de ácidos grasos poliinsaturados, con predominancia del ácido linoleico y α-linolénico, ácidos grasos esenciales.Numerous natural compounds found in fruits, grains and vegetables have antioxidant activity. This work aimed to characterize jabuticaba seeds (Myrciaria cauliflora Berg by proximate composition, antioxidant activity and fatty acids profile of their extracted oil. To obtain the extract, the dehydrated and triturated seeds were extracted with ethyl alcohol for 30 min, at a proportion of 1:3 of seeds:ethyl alcohol, under continuous agitation, at room temperature. Afterwards, the mixture was filtered and the supernatant dehydrated at 40 ºC aiming to determine, by direct weighing, the extract’s dry matter yield. According to the results, the jabuticaba seeds are an important source of total carbohydrates, and also presented relevant antioxidant activity. In the jabuticaba seeds oil, a significant percentage of polyunsaturated fatty acids stood out, with

  11. [The Omega "Omega" pulley plasty. A new technique to increase the diameter of the annular flexor digital pulleys].

    Science.gov (United States)

    Bakhach, J; Sentucq-Rigal, J; Mouton, P; Boileau, R; Panconi, B; Guimberteau, J C

    2005-12-01

    The authors report a new technique of pulley plasty of the flexor digital system. It is not an operative procedure to reconstruct a damaged pulley but an original way to expand the volume of an intact pulley in order to adapt its volume to the diameter of the repaired flexor tendon. The flexor tendons ruptures in Verdan zone II and particularly in Tang zones IIA and IIB are often accompanied by an osteofibrous tunnel injury. Initially, the tendon sheath closure was advised after tendons repair. This sheath recovery had to have an effect on tendons nutrition by establishing the synovial cavity continuity and particularly to protect the tendons from adhesions formation. The closure of the digital tube was rapidly shown to be unnecessary creating an obstacle to the tendons movements without any effect on tendons healing. In primary tendon management, the tendon repair is associated with an increase of the tendon diameter. An incongruence appears with the surrounding digital tube with gliding resistance complicating the tendon injury recovery. In secondary tendon injury management, the flexor digital tube is subject to healing and inflammatory process. This situation with the absence of the flexor tendon generates a retraction with a collapse of the digital tunnel over the injured area. This incongruence between the repaired flexor tendons and the narrowed digital tube required a release of the retracted zone to restore an adequate volume. The only way reported is the "Venting" of a part or the total length of the pulley. This procedure even if it resolves the tendon gliding resistance, is still unacceptable. Indeed it destroys an important anatomical structure of the flexor tendon dynamic system. The flexor pulley Omega plasty "Omega" consists in releasing the lateral palmar attachment of the pulley enhancing its internal volume and increasing the flexor tendon gliding area. The digital tube is composed by the succession of five annular and three cruciform pulleys

  12. Observation of the Omega(b)- Baryon and Measurement of the Properties of the Xi(b)- and Omega(b)- Baryons

    Energy Technology Data Exchange (ETDEWEB)

    Aaltonen, T.; /Helsinki Inst. of Phys.; Adelman, Jahred A.; /Chicago U., EFI; Akimoto, T.; /Tsukuba U.; Alvarez Gonzalez, B.; /Cantabria Inst. of Phys.; Amerio, S.; /INFN, Padua; Amidei, Dante E.; /Michigan U.; Anastassov, A.; /Northwestern U.; Annovi, Alberto; /Frascati; Antos, Jaroslav; /Comenius U.; Apollinari, G.; /Fermilab; Apresyan, A.; /Purdue U. /Waseda U.

    2009-05-01

    The authors report the observation of the bottom, doubly-strange baryon {Omega}{sub b}{sup -} through the decay chain {Omega}{sub b}{sup -} {yields} J/{psi}{Omega}{sup -}, where J/{psi} {yields} {mu}{sup +} {mu}{sup -}, {Omega}{sup -} {yields} {Lambda}K{sup -}, and {Lambda} {yields} p {pi}{sup -}, using 4.2 fb{sup -1} of data from p{bar p} collisions at {radical}s = 1.96 TeV, and recorded with the Collider Detector at Fermilab. A signal is observed whose probability of arising from a background fluctuation is 4.0 x 10{sup -8}, or 5.5 Gaussian standard deviations. The {Omega}{sub b}{sup -} mass is measured to be 6054.4 {+-} 6.8(stat.) {+-} 0.9(syst.) MeV/c{sup 2}. The lifetime of the {Omega}{sub b}{sup -} baryon is measured to be 1.13{sub -0.40}{sup +0.53}(stat.) {+-} 0.02(syst.) ps. In addition, for the {Xi}{sub b}{sup -} baryon they measure a mass of 5790.9 {+-} 2.6(stat.) {+-} 0.8(syst.) MeV/c{sup 2} and a lifetime of 1.56{sub -0.25}{sup +0.27}(stat.) {+-} 0.02(syst.) ps.

  13. Efficacy of nutritional supplementation with omega-3 and omega-6 fatty acids in dry eye syndrome: a systematic review of randomized clinical trials.

    Science.gov (United States)

    Molina-Leyva, Ignacio; Molina-Leyva, Alejandro; Bueno-Cavanillas, Aurora

    2017-12-01

    To critically appraise scientific evidence regarding the efficacy of nutritional supplementation with omega-3 and omega-6 fatty acids for the treatment of dry eye syndrome (DES). A systematic review of randomized clinical trials was performed. Two independent reviewers selected and analysed the scientific papers that met inclusion and exclusion criteria. Objective and subjective efficacy outcomes were assessed. The trials involved a total of 2591 patients in fifteen independent studies. All studies were published between 2005 and 2015. The supplements used were mostly omega-3 and omega-6 in different proportions. Subjective improvement was measured using mainly Ocular Surface Disease Index (OSDI) test and Dry Eye Severity Score (DESS) test: significant differences in favour of the experimental group were found in seven of the studies. The objective amelioration was assessed by lacrimal function parameters: Tear break-up time (TBUT) significantly increased in nine studies and Schirmer's test in four studies. We observed a discrete improvement in the parameters of tear function. Scientific evidence is not strong enough to systematically recommend the use of omega-3 and omega-6 fatty acids as a standalone treatment of DES independently from its aetiology. However, they could be considered as an effective alternative to topical treatment in patients with DES secondary to certain pathologies. © 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  14. Omega-3 Index and Obstructive Sleep Apnea: A Cross-Sectional Study.

    Science.gov (United States)

    Tittus, Janine; Huber, Marie Theres; Storck, Klaus; Köhler, Anton; Köhler, Jan M; von Arnim, Thomas; von Schacky, Clemens

    2017-10-15

    Erythrocyte levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (Omega-3 Index) were previously found to be associated with obstructive sleep apnea (OSA) at very low levels (Omega-3 Index. These comorbidities can be improved by increasing intake of EPA and DHA, and thus the Omega-3 Index, preferably to its target range of 8% to 11%. Symptoms of OSA might improve by increasing the Omega-3 Index, but more research is needed. In our sleep laboratory, 357 participants with OSA were recruited, and data from 315 participants were evaluated. Three categories of OSA (none/ mild, moderate, severe) were defined based on apnea-hypopnea index. Anthropometrics and lifestyle characteristics (smoking, alcohol, fish intake, omega-3 supplementation) were recorded. Erythrocyte fatty acid compositions were assessed with the HS-Omega-3 Index methodology. The mean Omega-3 Index in all 3 categories of OSA was 5.7%, and no association with OSA was found. There were more male participants with severe OSA (79.7%, P = .042) than females, and participants with severe OSA had a significantly higher body mass index (32.11 ± 6.39 kg/m2, P = .009) than participants with mild or moderate OSA. Lifestyle characteristics were not significantly different. In contrast to our hypothesis, an Omega-3 Index of 5.7% was not associated with OSA severity. Previously, an Omega-3 Index Omega-3 Index > 5.7% in an intervention trial with EPA and DHA in OSA, comorbidities of OSA suggest a target range of 8% to 11%.

  15. Omega-3 Fatty Acid Content in Various Tissues of Different Persian Gulf Fish

    Directory of Open Access Journals (Sweden)

    MJ Zibaee Nezhad

    2008-11-01

    Full Text Available Background: The fatty acids of omega-3 family have high nutritional value and can prevent coronary heart disease.These fatty acids are found in various fish and sea foods. To investigate the level of omega-3 fatty acids indifferent kind of fish head, muscle and liver from 30 species of fish collected from Persian Gulf.Material and Methods: In this experimental study, the fish were collected by hunting from Boushehr and Hormozgansea ports. Their head, muscle and liver fatty acids were determined on their methylated fatty acids dissolvedin N-hexin. Quantitative analysis of fatty acids was performed by gas chromatography (GC with methylmyristateused as the reference material in this analysis and the qualitative analysis of fatty acids was done bygas chromatography and mass spectrometer (GC- mass and cod liver oil which contained all of omega-3 fattyacids used as standard.Results: Our study showed that some fish were good sources of omega-3 fatty acids and Trout (Ghezel-ALA,Bartail flathead (Zaminkan-e-domnavari, Malabar blood snapper (Sorkhoo malabari had maximum levels ofomega-3 in all body tissues. Other types of fish were rich in omega 3 fatty acids in separate organs, such as liverin Bartail flathead (Zaminkan-e-domnavari, head in Sillago Sihama (Shoort and muscle in Trout (Ghezel-ALA. In contrast, lesser amount of omega 3 fatty acids is found in tissues of other species of fish such as Silverpomfret (Halva sefid, Longfin trevally (Gish-e-derazbale and Xiphophorus Hellerii (Dom-shamshiri.Conclusion: This research showed that the liver of fish had the highest level of omega-3 fatty acids and fish musclecontained more omega-3 fatty acids than the head. Thus for having maximum levels of omega-3 fatty acids inthe diet, all fish tissues can be served. As liver and head of fish are not usually consumed, it is recommended thatsuch organs be used for preparation of omega 3-containing cardio supportive supplements.

  16. Recent Advances in Omega-3: Health Benefits, Sources, Products and Bioavailability

    Directory of Open Access Journals (Sweden)

    Peter D. Nichols

    2014-09-01

    Full Text Available The joint symposium of The Omega-3 Centre and the Australasian Section American Oil Chemists Society; Recent Advances in Omega-3: Health Benefits, Sources, Products and Bioavailability, was held November 7, 2013 in Newcastle, NSW, Australia. Over 115 attendees received new information on a range of health benefits, aquaculture as a sustainable source of supply, and current and potential new and novel sources of these essential omega-3 long-chain (LC, ≥C20 polyunsaturated fatty acid nutrients (also termed LC omega-3. The theme of “Food versus Fuel” was an inspired way to present a vast array of emerging and ground breaking Omega-3 research that has application across many disciplines. Eleven papers submitted following from the Omega-3 Symposium are published in this Special Issue volume, with topics covered including: an update on the use of the Omega-3 Index (O3I, the effects of dosage and concurrent intake of vitamins/minerals on omega-3 incorporation into red blood cells, the possible use of the O3I as a measure of risk for adiposity, the need for and progress with new land plant sources of docosahexaenoic acid (DHA, 22:6ω3, the current status of farmed Australian and New Zealand fish, and also supplements, in terms of their LC omega-3 and persistent organic pollutants (POP content, progress with cheap carbon sources in the culture of DHA-producing single cell organisms, a detailed examination of the lipids of the New Zealand Greenshell mussel, and a pilot investigation of the purification of New Zealand hoki liver oil by short path distillation. The selection of papers in this Special Issue collectively highlights a range of forward looking and also new and including positive scientific outcomes occurring in the omega-3 field.

  17. BPS States in the Duality Web of the Omega deformation

    CERN Document Server

    Hellerman, Simeon; Reffert, Susanne

    2013-01-01

    In this note, we study different limits of an Omega-deformed (2,0) six-dimensional gauge theory realized in a M-theory fluxtrap background. Via a chain of dualities, we connect the Omega-deformed SYM to a new four-dimensional gauge theory which we refer to as the reciprocal gauge theory. This theory has several properties in common with Liouville field theory, such as its gauge coupling b^2 =\\epsilon_2 / \\epsilon_1, and its behavior under S-duality. Finally, we realize the BPS states on the SYM side of the AGT correspondence and follow them along the chain of dualities. In the fluxtrap frame, we are dealing with two distinct types of states localized in different radial positions, while in the reciprocal frame, we find single states carrying both charges localized in one place which appear to be perturbatively stable. Our microscopic picture of the small-b limit exhibits semiclassically BPS bound states, which are not visible at the level of the partition function.

  18. Heterologous Reconstitution of Omega-3 Polyunsaturated Fatty Acids in Arabidopsis

    Directory of Open Access Journals (Sweden)

    Sun Hee Kim

    2015-01-01

    Full Text Available Reconstitution of nonnative, very-long-chain polyunsaturated fatty acid (VLC-PUFA biosynthetic pathways in Arabidopsis thaliana was undertaken. The introduction of three primary biosynthetic activities to cells requires the stable coexpression of multiple proteins within the same cell. Herein, we report that C22 VLC-PUFAs were synthesized from C18 precursors by reactions catalyzed by Δ6-desaturase, an ELOVL5-like enzyme involved in VLC-PUFA elongation, and Δ5-desaturase. Coexpression of the corresponding genes (McD6DES, AsELOVL5, and PtD5DES under the control of the seed-specific vicilin promoter resulted in production of docosapentaenoic acid (22:5 n-3 and docosatetraenoic acid (22:4 n-6 as well as eicosapentaenoic acid (20:5 n-3 and arachidonic acid (20:4 n-6 in Arabidopsis seeds. The contributions of the transgenic enzymes and endogenous fatty acid metabolism were determined. Specifically, the reasonable synthesis of omega-3 stearidonic acid (18:4 n-3 could be a useful tool to obtain a sustainable system for the production of omega-3 fatty acids in seeds of a transgenic T3 line 63-1. The results indicated that coexpression of the three proteins was stable. Therefore, this study suggests that metabolic engineering of oilseed crops to produce VLC-PUFAs is feasible.

  19. Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis

    Directory of Open Access Journals (Sweden)

    Amit Sharma

    2016-05-01

    Full Text Available Cytochrome P450 (CYP monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs that have multiple biological actions. The present study determined the ability of the most abundant EDP regioisomer, 19,20-EDP to reduce kidney injury in an experimental unilateral ureteral obstruction (UUO renal fibrosis mouse model. Mice with UUO developed kidney tubular injury and interstitial fibrosis. UUO mice had elevated kidney hydroxyproline content and five-times greater collagen positive fibrotic area than sham control mice. 19,20-EDP treatment to UUO mice for 10 days reduced renal fibrosis with a 40%–50% reduction in collagen positive area and hydroxyproline content. There was a six-fold increase in kidney α-smooth muscle actin (α-SMA positive area in UUO mice compared to sham control mice, and 19,20-EDP treatment to UUO mice decreased α-SMA immunopositive area by 60%. UUO mice demonstrated renal epithelial-to-mesenchymal transition (EMT with reduced expression of the epithelial marker E-cadherin and elevated expression of multiple mesenchymal markers (FSP-1, α-SMA, and desmin. Interestingly, 19,20-EDP treatment reduced renal EMT in UUO by decreasing mesenchymal and increasing epithelial marker expression. Overall, we demonstrate that a novel omega-3 fatty acid metabolite 19,20-EDP, prevents UUO-induced renal fibrosis in mice by reducing renal EMT.

  20. Características clínicas, bioquímicas y epidemiológicas de un grupo de pacientes con diagnóstico imaginológico de hígado graso

    Directory of Open Access Journals (Sweden)

    Juan Carlos Restrepo

    2001-04-01

    Full Text Available En nuestro medio, la esteatosis o infiltración hepática grasa se
    convierte casi siempre en un hallazgo imaginológico incidental, al cual
    se la da muy poca importancia desde el punto de vista clínico, y por
    ende no se realizan estudios posteriores para determinar su causa, las condiciones asociadas que lo expliquen (1, y mucho menos se realiza biopsia hepática para determinar, cuáles de estos pacientes tienen esteatohepatitis, algún grado de fibrosis o incluso cirrosis. Este trabajo tuvo como objetivo describir las características epidemiológicas, clínicas y bioquímicas de un grupo de pacientes con diagnóstico imaginológico de hígado graso.

  1. Evaluación de un Extensor Graso sobre las Propiedades de Calidad del Chorizo Tipo Antioqueño Evaluation of a Fat Extender on the Quality Properties of Chorizo Antioqueño Type

    Directory of Open Access Journals (Sweden)

    Waldir Augusto Pacheco Pérez

    2011-12-01

    Full Text Available Se estudió el efecto de un extensor de grasa elaborado con tocino dorsal de cerdo y una mezcla de alginato de sodio y carbonato de calcio, sobre las propiedades de calidad de un chorizo tipo Antioqueño, con el fin de desarrollar un producto reducido en grasa. Los chorizos elaborados con el extensor graso fueron comparados contra un chorizo formulado con tocino de cerdo. La composición proximal, contenido de colesterol, perfil de ácidos grasos, valor energético, pérdidas por cocción, pérdidas por purga, textura, color y atributos sensoriales fueron analizados en los productos obtenidos. Los datos reportados en cada una de las mediciones fueron analizados a través de análisis de varianza de una vía. Diferencias significativas (PThe effect of a fat extender elaborated with pork backfat and a mixture of sodium alginate and calcium carbonate on the quality properties of a chorizo Antioqueño type was studied, with the purpose of developing a product reduced in fat. The chorizos elaborated with the fat extender was compared against a chorizo elaborated with pork backfat. The proximal composition, content of cholesterol, profile of fatty acids, energy value, cooking loss, purge losses, texture, color and sensorial attributes were analyzed in the obtained products. The data reported in each of the measurements were analyzed by one way analysis of variance. Significant differences (P<0,05 were found in the content of fat and in the profile of fatty acids, in the texture properties, so much at instrumental level as sensory. Also in the sensory attributes such as appearance, odour, taste and fatty sensation, as well as a reduction in the energy value, while an increase in the cooking loss was observed.

  2. Synthesis and characterization of PdAg as a catalyst for oxygen reduction reaction in acid medium; Sintesis y caracterizacion de PdAg como catalizador para la reaccion de reduccion de oxigeno en medio acido

    Energy Technology Data Exchange (ETDEWEB)

    Martinez-Casillas, D. C.; Vazquez-Huerta, G.; Solorza-Feria, O. [Centro de Investigacion y de Estudios Avanzados del IPN, Mexico D.F. (Mexico)]. E-mail: dcmartinez@cinvestav.mx

    2009-09-15

    This work presents the synthesis of the binary compound PdAg and the electrochemical characterization for oxygen reduction reaction (ORR) in acid medium. The catalyst is obtained from the reduction of Pd(NO{sub 3}){sub 2}·2H{sub 2}O and AgNO{sub 3} with NaBH{sub 4} in THF. The synthesized compound was physically characterized with transmission electron microscopy (TEM), sweep electron microscopy (SEM) and x-ray diffraction (XRD) of powder. Electrochemical studies were conducted to determine the catalytic activity and intrinsic properties of the PdAg material for the ORR in acid medium using cyclic voltamperometry (CV), rotary disc electrode (RDE) and electrochemical impedance spectroscopy (EIS) in a solution of H{sub 2}SO{sub 4} 0.5 M at 25 degrees Celsius. The electrochemical current-potential responses were compared to those of palladium and platinum. The kinetic results showed an increase in the performance of the bimetallic electrocatalyst containing Ag as compared to pure Pd, but less than that obtained with nanometric Pt. The Tafel slopes obtained are roughly120 mV dec-1, similar to that reported for Pt and Pd and for other Ru-based electrocatalysts. [Spanish] En este trabajo se presentan la sintesis del compuesto binario PdAg y su caracterizacion electroquimica para la reaccion de reduccion de oxigeno (RRO) en medio acido. El catalizador se obtuvo a partir de la reduccion de Pd(NO{sub 3}){sub 2}·2H{sub 2}O y AgNO{sub 3} con NaBH{sub 4} en THF. El compuesto sintetizado se caracterizo fisicamente por microscopia electronica de transmision (MET), microscopia electronica de barrido (MEB) y difraccion de rayos X (DRX) de polvos. Se realizaron estudios electroquimicos para determinar la actividad catalitica y las propiedades intrinsecas del material de PdAg para la reaccion de reduccion de oxigeno (RRO) en medio acido, utilizando las tecnicas de voltamperometria ciclica (VC), electrodo disco rotatorio (EDR) y espectroscopia de impedancia electroquimica (EIE), en

  3. The role of omega-3 fatty acids in adult hippocampal neurogenesis

    Directory of Open Access Journals (Sweden)

    Dyall Simon C.

    2011-09-01

    Full Text Available Neurogenesis occurs in limited areas of the adult mammalian brain, and has been reported in the hippocampus of rodents and man. Neurogenesis is enhanced in conditions associated with enhanced synaptic plasticity and following neuronal injury, suggesting a role for neurogenesis in cognition and brain repair. Omega-3 polyunsaturated fatty acids (PUFAs have been shown to promote hippocampal neurogenesis in a variety of models. Importantly, recent work has shown that the fat-1 transgenic mouse, an animal model of endogenous omega-3 PUFA enrichment, exhibits enhanced neurogenesis, with concomitant improvements in spatial memory compared to wild type mice. During ageing, the rate of neurogenesis declines significantly and there is a strong correlation between memory impairment in hippocampal-dependent tasks and this decline. Interestingly, there is a strong correlation between omega-3 PUFA and hippocampal-dependent memory tasks, and we have recently shown that supplementation of aged rats with omega-3 PUFAs partially reverses the age-related decline in neurogenesis. Thus omega-3 PUFAs positively influence neurogenesis, and these effects may contribute to improved cognitive performance. However, the mechanisms by which omega-3 PUFAs regulate neurogenesis remain unclear, although a number or putative targets have been suggested. The aims of this paper are to review the role of omega-3 PUFA in hippocampal neurogenesis, and explore some of the potential mechanisms of action which may underlie the observed effects.

  4. Omega-3 versus isoflavones in the control of vasomotor symptoms in postmenopausal women.

    Science.gov (United States)

    Palacios, S; Lilue, M; Mejia, A; Menendez, C

    2017-12-01

    Determine the efficacy and tolerability of omega-3 fatty acids versus soybean isoflavones in reducing the vasomotor symptoms (VMSs) frequency in postmenopausal women. A randomized, prospective, two-arm study was performed in healthy postmenopausal women aged 45-65. The two arms were: two capsules/day of omega-3 (425 mg of omega-3/capsule) administered orally (n = 38) and two tablets/day of soybean isoflavones (54.4 mg of isoflavones/tablet) (n = 30), over 16 weeks. The mean baseline frequency of moderate and severe VMSs per week in the omega-3 group was 24.56 and 23.90, respectively, and 19.65 and 19.51 in the isoflavone group. After 4 months, the reduction in moderate and severe hot flashes with omega-3 was significant (p Omega-3 did not demonstrate significant efficacy differences versus isoflavones over time. The use of omega-3 has a beneficial effect on hot flash reduction after 4 months of treatment. This is comparable to the benefits found with soybean isoflavones after 3-4 weeks and after 4 months in severe hot flash women, but higher than those found with soybean isoflavones in moderate symptom women.

  5. Omega-3 polyunsaturated fatty acids for cardiovascular diseases: present, past and future.

    Science.gov (United States)

    Watanabe, Yasuhiro; Tatsuno, Ichiro

    2017-08-01

    Large-scale epidemiological studies on Greenlandic, Canadian and Alaskan Eskimos have examined the health benefits of omega-3 fatty acids consumed as part of the diet, and found statistically significant relative reduction in cardiovascular risk in people consuming omega-3 fatty acids. Areas covered: This article reviews studies on omega-3 fatty acids during the last 50 years, and identifies issues relevant to future studies on cardiovascular (CV) risk. Expert commentary: Although a meta-analysis of large-scale prospective cohort studies and randomized studies reported that fish and fish oil consumption reduced coronary heart disease-related mortality and sudden cardiac death, omega-3 fatty acids have not yet been shown to be effective in secondary prevention trials on patients with multiple cardiovascular disease (CVD) risk factors. The ongoing long-term CV interventional outcome studies investigate high-dose, prescription-strength omega-3 fatty acids. The results are expected to clarify the potential role of omega-3 fatty acids in reducing CV risk. The anti-inflammatory properties of omega-3 fatty acids are also important. Future clinical trials should also focus on the role of these anti-inflammatory mediators in human arteriosclerotic diseases as well as inflammatory diseases.

  6. Omega-3 Fatty Acids and Depression: Scientific Evidence and Biological Mechanisms

    Science.gov (United States)

    Galvano, Fabio; Marventano, Stefano; Malaguarnera, Michele; Bucolo, Claudio; Drago, Filippo; Caraci, Filippo

    2014-01-01

    The changing of omega-6/omega-3 polyunsaturated fatty acids (PUFA) in the food supply of Western societies occurred over the last 150 years is thought to promote the pathogenesis of many inflammatory-related diseases, including depressive disorders. Several epidemiological studies reported a significant inverse correlation between intake of oily fish and depression or bipolar disorders. Studies conducted specifically on the association between omega-3 intake and depression reported contrasting results, suggesting that the preventive role of omega-3 PUFA may depend also on other factors, such as overall diet quality and the social environment. Accordingly, tertiary prevention with omega-3 PUFA supplement in depressed patients has reached greater effectiveness during the last recent years, although definitive statements on their use in depression therapy cannot be yet freely asserted. Among the biological properties of omega-3 PUFA, their anti-inflammatory effects and their important role on the structural changing of the brain should be taken into account to better understand the possible pathway through which they can be effective both in preventing or treating depression. However, the problem of how to correct the inadequate supply of omega-3 PUFA in the Westernized countries' diet is a priority in order to set food and health policies and also dietary recommendations for individuals and population groups. PMID:24757497

  7. Association between Blood Omega-3 Index and Cognition in Typically Developing Dutch Adolescents

    Directory of Open Access Journals (Sweden)

    Inge S. M. van der Wurff

    2016-01-01

    Full Text Available The impact of omega-3 long-chain polyunsaturated fatty acids (LCPUFAs on cognition is heavily debated. In the current study, the possible association between omega-3 LCPUFAs in blood and cognitive performance of 266 typically developing adolescents aged 13–15 years is investigated. Baseline data from Food2Learn, a double-blind and randomized placebo controlled krill oil supplementation trial in typically developing adolescents, were used for the current study. The Omega-3 Index was determined with blood from a finger prick. At baseline, participants finished a neuropsychological test battery consisting of the Letter Digit Substitution Test (LDST, D2 test of attention, Digit Span Forward and Backward, Concept Shifting Test and Stroop test. Data were analyzed with multiple regression analyses with correction for covariates. The average Omega-3 Index was 3.83% (SD 0.60. Regression analyses between the Omega-3 Index and the outcome parameters revealed significant associations with scores on two of the nine parameters. The association between the Omega-3 Index and both scores on the LDST (β = 0.136 and p = 0.039, and the number of errors of omission on the D2 (β = −0.053 and p = 0.007. This is a possible indication for a higher information processing speed and less impulsivity in those with a higher Omega-3 Index.

  8. Conducting omega-3 clinical trials with cardiovascular outcomes: Proceedings of a workshop held at ISSFAL 2014.

    Science.gov (United States)

    Rice, Harry B; Bernasconi, Aldo; Maki, Kevin C; Harris, William S; von Schacky, Clemens; Calder, Philip C

    2016-04-01

    In contrast to earlier long-chain (LC) omega-3 (i.e. EPA and DHA) investigations, some recent studies have not demonstrated significant effects of EPA and DHA on cardiovascular disease (CVD) outcomes. The neutral findings may have been due to experimental design issues, such as: maintenance on aggressive cardiovascular drug treatment overshadowing the benefits of LC omega-3s, high background LC omega-3 intake, too few subjects in the study, treatment duration too short, insufficient LC omega-3 dosage, increase in omega-6 fatty acid intake during the study, failure to assess the LC omega-3 status of the subjects prior to and during treatment and lack of clarity concerning which mechanisms were expected to produce benefits. At the 11th ISSFAL Congress, a workshop was held on conducting LC omega-3 clinical trials with cardiovascular outcomes, with the goal of gaining a better understanding concerning aspects of experimental design that should be considered when planning clinical studies related to EPA and DHA and potential cardiovascular benefits. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  9. Study of the process $e^+ e^- \\to \\omega\\pi^0 $ with the KLOE detector

    CERN Document Server

    Ambrosino, F; Antonelli, M; Archilli, F; Bacci, C; Beltrame, P; Bencivenni, G; Bertolucci, S; Bini, C; Bloise, C; Bocchetta, S; Bocci, V; Bossi, F; Branchini, P; Caloi, R; Campana, P; Capon, G; Capussela, T; Ceradini, F; Chi, S; Chiefari, G; Ciambrone, P; De Lucia, E; De Santis, A; De Simone, P; De Zorzi, G; Denig, A; Di Domenico, A; Di Donato, C; Di Falco, S; Di Micco, B; Doria, A; Dreucci, M; Felici, G; Ferrari, A; Ferrer, M L; Finocchiaro, G; Fiore, S; Forti, C; Franzini, P; Gatti, C; Gauzzi, P; Giovannella, S; Gorini, E; Graziani, E; Incagli, M; Kluge, W; Kulikov, V; Lacava, F; Lanfranchi, G; Lee-Franzini, J; Leone, D; Martini, M; Massarotti, P; Mei, W; Meola, S; Miscetti, S; Moulson, M; Müller, S; Murtas, F; Napolitano, M; Nguyen, F; Palutan, M; Pasqualucci, E; Passeri, A; Patera, A V; Perfetto, F; Primavera, M; Santangelo, P; Saracino, G; Sciascia, B; Sciubba, A; Scuri, F; Sfiligoi, I; Spadaro, T; Testa, M; Tortora, L; Valente, P; Valeriani, B; Venanzoni, G; Versaci, R; Xu, G

    2007-01-01

    Using $\\sim$ 600 pb$^{-1}$ collected with the KLOE detector at DA$\\Phi$NE, we have studied the production cross section of $\\pi^+\\pi^-\\pi^0\\pi^0$ and $\\pi^0\\pi^0\\gamma$ final states in $e^+ e^-$ collisions at center of mass energies between 1000 and 1030 MeV. By fitting the observed interference pattern around $M_\\phi$ for both final states, we extract a measurement (preliminary) for the ratio $\\Gamma(\\omega\\to\\pi^0\\gamma)/\\Gamma(\\omega\\to\\pi^+\\pi^-\\pi^0) = 0.0934\\pm 0.0022$. Since these two final states represent the 98% of the $\\omega$ decay channels, we use unitarity to derive $BR(\\omega\\to\\pi^+\\pi^-\\pi^0)= (89.94\\pm 0.23)%$ and $BR(\\omega\\to\\pi^0\\gamma) = (8.40\\pm 0.19)%$. % Moreover, the parameters describing the \\eeto\\wpc reaction around $M_\\phi$ are used to extract the branching fraction for the OZI and G-parity violating $\\phi\\to\\omega\\pi^0$ decay: $BR(\\phi\\to\\omega\\pi^0) = (5.63\\pm 0.70)\\times 10^{-5}$.

  10. Association between Blood Omega-3 Index and Cognition in Typically Developing Dutch Adolescents.

    Science.gov (United States)

    van der Wurff, Inge S M; von Schacky, Clemens; Berge, Kjetil; Zeegers, Maurice P; Kirschner, Paul A; de Groot, Renate H M

    2016-01-02

    The impact of omega-3 long-chain polyunsaturated fatty acids (LCPUFAs) on cognition is heavily debated. In the current study, the possible association between omega-3 LCPUFAs in blood and cognitive performance of 266 typically developing adolescents aged 13-15 years is investigated. Baseline data from Food2Learn, a double-blind and randomized placebo controlled krill oil supplementation trial in typically developing adolescents, were used for the current study. The Omega-3 Index was determined with blood from a finger prick. At baseline, participants finished a neuropsychological test battery consisting of the Letter Digit Substitution Test (LDST), D2 test of attention, Digit Span Forward and Backward, Concept Shifting Test and Stroop test. Data were analyzed with multiple regression analyses with correction for covariates. The average Omega-3 Index was 3.83% (SD 0.60). Regression analyses between the Omega-3 Index and the outcome parameters revealed significant associations with scores on two of the nine parameters. The association between the Omega-3 Index and both scores on the LDST (β = 0.136 and p = 0.039), and the number of errors of omission on the D2 (β = -0.053 and p = 0.007). This is a possible indication for a higher information processing speed and less impulsivity in those with a higher Omega-3 Index.

  11. The Role for Dietary Omega-3 Fatty Acids Supplementation in Older Adults

    Directory of Open Access Journals (Sweden)

    Alessio Molfino

    2014-10-01

    Full Text Available Optimal nutrition is one of the most important determinants of healthier ageing, reducing the risk of disability, maintaining mental and physical functions, and thus preserving and ensuring a better quality of life. Dietary intake and nutrient absorption decline with age, thus increasing the risk of malnutrition, morbidity and mortality. Specific nutrients, particularly long-chain omega-3 polyunsaturated fatty acids (PUFAs, might have the potential of preventing and reducing co-morbidities in older adults. Omega-3 PUFAs are able to modulate inflammation, hyperlipidemia, platelet aggregation, and hypertension. Different mechanisms contribute to these effects, including conditioning cell membrane function and composition, eicosanoid production, and gene expression. The present review analyzes the influence of omega-3 PUFAs status and intake on brain function, cardiovascular system, immune function, muscle performance and bone health in older adults. Omega-3 FAs may have substantial benefits in reducing the risk of cognitive decline in older people. The available data encourage higher intakes of omega-3 PUFAs in the diet or via specific supplements. More studies are needed to confirm the role of omega-3 FAs in maintaining bone health and preventing the loss of muscle mass and function associated with ageing. In summary, omega-3 PUFAs are now identified as potential key nutrients, safe and effective in the treatment and prevention of several negative consequences of ageing.

  12. The role for dietary omega-3 fatty acids supplementation in older adults.

    Science.gov (United States)

    Molfino, Alessio; Gioia, Gianfranco; Rossi Fanelli, Filippo; Muscaritoli, Maurizio

    2014-10-03

    Optimal nutrition is one of the most important determinants of healthier ageing, reducing the risk of disability, maintaining mental and physical functions, and thus preserving and ensuring a better quality of life. Dietary intake and nutrient absorption decline with age, thus increasing the risk of malnutrition, morbidity and mortality. Specific nutrients, particularly long-chain omega-3 polyunsaturated fatty acids (PUFAs), might have the potential of preventing and reducing co-morbidities in older adults. Omega-3 PUFAs are able to modulate inflammation, hyperlipidemia, platelet aggregation, and hypertension. Different mechanisms contribute to these effects, including conditioning cell membrane function and composition, eicosanoid production, and gene expression. The present review analyzes the influence of omega-3 PUFAs status and intake on brain function, cardiovascular system, immune function, muscle performance and bone health in older adults. Omega-3 FAs may have substantial benefits in reducing the risk of cognitive decline in older people. The available data encourage higher intakes of omega-3 PUFAs in the diet or via specific supplements. More studies are needed to confirm the role of omega-3 FAs in maintaining bone health and preventing the loss of muscle mass and function associated with ageing. In summary, omega-3 PUFAs are now identified as potential key nutrients, safe and effective in the treatment and prevention of several negative consequences of ageing.

  13. A computational search for lipases that can preferentially hydrolyze long-chain omega-3 fatty acids from fish oil triacylglycerols.

    Science.gov (United States)

    Kamal, Md Zahid; Barrow, Colin J; Rao, Nalam Madhusudhana

    2015-04-15

    Consumption of long-chain omega-3 fatty acids is known to decrease the risk of major cardiovascular events. Lipases, a class of triacylglycerol hydrolases, have been extensively tested to concentrate omega-3 fatty acids from fish oils, under mild enzymatic conditions. However, no lipases with preference for omega-3 fatty acids selectivity have yet been discovered or developed. In this study we performed an exhaustive computational study of substrate-lipase interactions by docking, both covalent and non-covalent, for 38 lipases with a large number of structured triacylglycerols containing omega-3 fatty acids. We identified some lipases that have potential to preferentially hydrolyze omega-3 fatty acids from structured triacylglycerols. However omega-3 fatty acid preferences were found to be modest. Our study provides an explanation for absence of reports of lipases with omega-3 fatty acid hydrolyzing ability and suggests methods for developing these selective lipases. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. New analysis of the radiative decay $\\omega \\to \\eta\\gamma$ in proton-antiproton annihilation at rest

    CERN Document Server

    Case, T; Heinsius, F H; Kammel, P; Lakata, M T; Degener, T F; Koch, H; Kunze, M; Kurilla, U; Matthäy, H; Peters, K; Ratajczak, M; Stöck, H; Barnett, B M; Herz, M; Kalinowsky, H; Klempt, E; Pick, B; Strassburger, C; Suh, J S; Thoma, U; Witmack, K; Hidas, P; Baker, C A; Batty, C J; Doser, Michael; Kisiel, J; Landua, Rolf; Adomeit, J; Meier, J; Ouared, R; Seibert, R; Strohbusch, U; Abele, A; Bischoff, S; Blüm, H P; Engelhardt, D; Herbstrith, A; Holtzhaussen, C; Tischhäuser, M; Bugg, D V; Hodd, C; Zou Bing Song; Haddock, R P; Braune, K; Dünnweber, W; Faessler, M A; Hessey, N P; Jamnik, D; Kolo, C; Röthel, W; Völcker, C; Uman, I; Wallis-Plachner, S; Walther, D; Wiedner, U; Berdoz, A R; McCrady, R G; Meyer, C A; Suffert, Martin

    2000-01-01

    We report on a measurement of the branching ratio of the rare decay omega to eta gamma relative to the well known decay omega to pi /sup 0/ gamma . The omega 's are produced in pp to eta omega and pp to pi /sup 0/ omega . Eigenstate mixing and interference effects of the omega and rho /sup 0/ are taken into account, as well as coherent interference with the background. We find evidence for the non- resonant annihilation channel B(pp to eta eta gamma )=(3.5+or-1.3)*10 /sup -5/ and limit the value of B( omega to eta gamma ) to the range of (0.7 to 5.5)*10/sup -4/ depending on the degree of coherence with the background. (19 refs).

  15. The potential role of omega-3 fatty acids supplements in increasing athletic performance

    Directory of Open Access Journals (Sweden)

    Șerban GLIGOR

    2017-03-01

    Full Text Available Polyunsaturated omega-3 and omega-6 fatty acids are essential fatty acids that cannot be produced by the body itself and therefore must be provided through nutrition. Omega-6 and particularly omega-3 fatty acids have important roles in the organism, contributing to the maintenance and promotion of health. The optimal proportion of omega-6/omega-3 fatty acids is 2:1, or even better 1:1. They are involved in normal growth and development, play a role in the prevention of coronary and cardiovascular diseases, of diabetes mellitus, of arterial hypertension, arthritis and cancer. Omega-3 fatty acids mainly have an anti-inflammatory effect, but also act as hypolipidemic and antithrombotic agents. A potential role of omega-3 fatty acids is that of increasing physical performance. Their role in the physical activity refers on one side to the global health of athletes and on the other side to their anti-inflammatory effect, as high intensity physical exercise induces increased free-radical production and microtraumas, with the induction of an inflammatory status. The anti-inflammatory effect of these fatty acids manifests through an increased production of endogenous antioxidant enzymes, through decreasing the production of prostaglandins metabolites, decreasing the production of leukotriene B4, etc. They are also effective on reducing muscle pain post eccentric exercise and on decreasing the severity of bronchoconstriction induced by exercise, as well as improving pulmonary function variables. In conclusion it seems that supplementing diets with omega-3 fatty acids, apart from having benefic effects on health and on the prevention and management of certain affections, proves to be a beneficial for physical activity and athletic performance.

  16. Renal-protective and ameliorating impacts of omega-3 fatty acids against aspartame damaged MDCK cells.

    Science.gov (United States)

    Pandurangan, Muthuraman; Enkhtaivan, Gansukh; Veerappan, Muthuviveganandavel; Mistry, Bhupendra; Patel, Rahul; Moon, So Hyun; Nagajyothi, Patnamsetty Chidanandha; Kim, Doo Hwan

    2017-11-01

    Aspartame is widely used artificial sweeteners as food additives. Several researchers have pointed that the controversial report on the use of aspartame over more than decades. Omega-3 fatty acids are essential and unsaturated fatty acids, and it plays a remarkable role in vision, intelligence, neural development, and metabolism of neurotransmitters. Therefore, the present study was aimed to investigate the effect of omega-3 fatty acids on aspartame treated renal cells. Experimental groups were divided into three such as sham control, aspartame treated, and aspartame with omega-3 fatty acids. Cell viability was determined by sulforhodamine-b assay and flow cytometric analysis. The experimental results showed that the aspartame induced altered cell viability were reduced following treatment of aspartame with omega-3 fatty acids. Altered cell morphology was recovered by omega-3 fatty acids. DNA damage appeared in the highest concentration of aspartame used in this study. DNA damage characteristics such as comet tail and tiny head sections did not appear in the omega-3 fatty acids treated cells. Several microvilli and vesicular structures were found in aspartame treated cells. Altered morphology such as rounding, microvilli, and formation of dome-like structures did not appear in the omega-3 fatty acids with aspartame treated cells. Caspase-3 mRNA and protein expression were increased in aspartame treated cells, and these levels were reduced following omega-3 fatty acids treatment. Taking all these data together, it is suggested that the omega-3 fatty acids may be a therapeutic agent to reduce the aspartame induced biochemical and morphological alterations in normal renal cells. © 2017 BioFactors, 43(6):847-857, 2017. © 2017 International Union of Biochemistry and Molecular Biology.

  17. Omega-3 Fatty Acids for the Treatment of Depression: Systematic Review and Meta-Analysis

    Science.gov (United States)

    Bloch, Michael H.; Hannestad, Jonas

    2013-01-01

    We conducted a meta-analysis of randomized, placebo-controlled trials of omega-3 fatty acid treatment of major depressive disorder in order to determine efficacy and to examine sources of heterogeneity between trials. PubMED (1965-May 2010) was searched for randomized, placebo-controlled trials of omega-3 fatty acids for major depressive disorder. Our primary outcome measure was standardized mean difference in a clinical measure of depression severity. In stratified meta-analysis we examined the effects of trial duration, trial methodological quality, baseline depression severity, diagnostic indication, dose of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in omega-3 preparations, and whether omega-3 fatty acid was given as monotherapy or augmentation. In 13 randomized, placebo-controlled trials examining the efficacy of omega-3 fatty acids involving 731 participants, meta-analysis demonstrated no significant benefit of omega-3 fatty acid treatment compared to placebo (SMD=0.11, 95% CI: -0.04, 0.26). Meta-analysis demonstrated significant heterogeneity and publication bias. Nearly all evidence of omega-3 benefit was removed after adjusting for publication bias using the trim-and-fill method (SMD=0.01, 95% CI: -0.13, 0.15). Secondary analyses suggested a trend towards increased efficacy of omega-3 fatty acids in trials of lower methodological quality, trials of shorter duration, trials, which utilized completers rather than intention-to-treat analysis, and trials in which study participants had greater baseline depression severity, Current published trials suggest a small, non-significant benefit of omega-3 fatty acids for major depression. Nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias. PMID:21931319

  18. Marine Omega-3 Phospholipids: Metabolism and Biological Activities

    Directory of Open Access Journals (Sweden)

    Nils Hoem

    2012-11-01

    Full Text Available The biological activities of omega-3 fatty acids (n-3 FAs have been under extensive study for several decades. However, not much attention has been paid to differences of dietary forms, such as triglycerides (TGs versus ethyl esters or phospholipids (PLs. New innovative marine raw materials, like krill and fish by-products, present n-3 FAs mainly in the PL form. With their increasing availability, new evidence has emerged on n-3 PL biological activities and differences to n-3 TGs. In this review, we describe the recently discovered nutritional properties of n-3 PLs on different parameters of metabolic syndrome and highlight their different metabolic bioavailability in comparison to other dietary forms of n-3 FAs.

  19. The Role of Omega-3 Polyunsaturated Fatty Acids in Stroke

    Directory of Open Access Journals (Sweden)

    Jiyuan Bu

    2016-01-01

    Full Text Available Stroke is the third commonest cause of death following cardiovascular diseases and cancer. In particular, in recent years, the morbidity and mortality of stroke keep remarkable growing. However, stroke still captures people attention far less than cardiovascular diseases and cancer. Past studies have shown that oxidative stress and inflammation play crucial roles in the progress of cerebral injury induced by stroke. Evidence is accumulating that the dietary supplementation of fish oil exhibits beneficial effects on several diseases, such as cardiovascular diseases, metabolic diseases, and cancer. Omega-3 polyunsaturated fatty acids (n-3 PUFAs, the major component of fish oil, have been found against oxidative stress and inflammation in cardiovascular diseases. And the potential of n-3 PUFAs in stroke treatment is attracting more and more attention. In this review, we will review the effects of n-3 PUFAs on stroke and mainly focus on the antioxidant and anti-inflammatory effects of n-3 PUFAs.

  20. Phenolipids as antioxidants in omega-3 enriched food products

    DEFF Research Database (Denmark)

    Sørensen, Ann-Dorit Moltke; Aleman, M.; Durand, E.

    acid and its esters, caffeates, in two different fish-oil-enriched food products: mayonnaise and milk. Lipid oxidation was evaluated from 3 parameters measured over storage time: peroxide value, volatiles and tocopherol concentrations. The results demonstrate the influence of the complex emulsions......Foods containing omega-3 PUFA are highly susceptible to oxidation. This causes formation of undesirable flavors and loss of health-beneficial fatty acids. To protect these food products, antioxidant addition may be a solution. Lately, extensive work has been performed on phenolipids...... and their efficacy in model emulsion systems. Since the polar paradox hypothesis was a simplified statement of the antioxidant efficacy in emulsions, a new term, “cut-off effect”, was introduced. The cut-off effect describes the efficacy of phenolipids in simple emulsions. However, most food products consist...

  1. Confidence Intervals for Omega Coefficient: Proposal for Calculus.

    Science.gov (United States)

    Ventura-León, José Luis

    2018-01-01

    La confiabilidad es entendida como una propiedad métrica de las puntuaciones de un instrumento de medida. Recientemente se viene utilizando el coeficiente omega (ω) para la estimación de la confiabilidad. No obstante, la medición nunca es exacta por la influencia del error aleatorio, por esa razón es necesario calcular y reportar el intervalo de confianza (IC) que permite encontrar en valor verdadero en un rango de medida. En ese contexto, el artículo plantea una forma de estimar el IC mediante el método de bootstrap para facilitar este procedimiento se brindan códigos de R (un software de acceso libre) para que puedan realizarse los cálculos de una forma amigable. Se espera que el artículo sirva de ayuda a los investigadores de ámbito de salud.

  2. [Role of omega-3 fatty acids in cardiovascular disease prevention].

    Science.gov (United States)

    Piñeiro-Corrales, Guadalupe; Lago Rivero, N; Culebras-Fernández, Jesús M

    2013-01-01

    Fatty acids, in addition to its known energy value and its structural function, have other beneficial properties. In particular, the polyunsaturated fatty acids omega-3 acting on the cardiovascular apparatus through many channels exerting a protective effect against cardiovascular risk. The benefits associated with the reduction in cardiac mortality and sudden death particular, are related to the incorporation of EPA and DHA in phospholipid membrane of cardiomyocytes. An index is established that relates the percentage of EPA + DHA of total fatty acids in erythrocytes and risk of death from cardiovascular disease may layering in different degrees. Therefore, the primary source of fatty fish w-3 PUFA, behaves like a reference food in cardiosaludables diets. Copyright © AULA MEDICA EDICIONES 2013. Published by AULA MEDICA. All rights reserved.

  3. Global Hybrid HRSC+OMEGA Image Mosaics of Mars

    Science.gov (United States)

    McGuire, P. C.; Walter, S. H. G.; van Gasselt, S.; Dunke, A.; Dunker, T.; Gross, C.; Michael, G.; Wendt, L.; Audouard, J.; Ody, A.; Poulet, F.

    2014-04-01

    The High Resolution Stereo Camera (HRSC) on the Mars Express (MEx) orbiter has acquired 3640 images (with 'preliminary level 4' processing as described in [1]) of the Martian surface since arriving in orbit in 2003, covering over 90% of the planet [2]. At resolutions that can reach 10 meters/pixel, these MEx/HRSC images [3-4] are constructed in a pushbroom manner from 9 different CCD line sensors, including a panchromatic nadir-looking (Pan) channel, 4 color channels (R, G, B, IR), and 4 other panchromatic channels for stereo imaging or photometric imaging. In [5], we discussed our approach towards automatically mosaicking hundreds of the MEx/HRSC Pan or RGB images together. Herein, we present our latest results using this approach (Fig. 1; PDF is zoomable). Currently, our best results consist of adding a high-pass-filtered version of the HRSC mosaic to a low-pass-filtered version of the MEx/OMEGA [6] global mosaic.

  4. Overpopulation of $\\bar \\Omega$ in pp collisions a way to distinguish statistical hadronization from string dynamics

    CERN Document Server

    Bleicher, M; Keränen, A; Aichelin, Jörg; Bass, S A; Becattini, F; Redlich, Krzysztof; Werner, K

    2002-01-01

    The $\\bar{\\Omega}/\\Omega$ ratio originating from string decays is predicted to be larger than unity in proton proton interactions at SPS energies ($E_{\\rm lab}$=160 GeV). The anti-omega dominance increases with decreasing beam energy. This surprising behavior is caused by the combinatorics of quark-antiquark production in small and low-mass strings. Since this behavior is not found in a statistical description of hadron production in proton proton collisions, it may serve as a key observable to probe the hadronization mechanism in such collisions.

  5. Baseline omega-3 index correlates with aggressive and attention deficit disorder behaviours in adult prisoners.

    Directory of Open Access Journals (Sweden)

    Barbara J Meyer

    Full Text Available There is emerging evidence that the supplementation of omega-3 contributes to a decrease in aggressive behaviour in prison populations. A challenge of such research is achieving statistical power against effect sizes which may be affected by the baseline omega-3 index. There are no published data on the blood omega-3 index with studies of this kind to assess the variability of the blood omega-3 index in conjunction with aggression and attention deficit assessments.To determine if the variance of the omega-3 index is correlated with aggressive and attention deficit behaviour in a prison population.136 adult male prisoners were recruited from South Coast Correctional Centre (SCCC, NSW Australia. A 7 point categorisation was used to quantify levels of aggressive behaviour (4 weeks from individual SCCC case notes, whereby higher scores correspond to increasingly aggressive behaviour. Study participants completed the Aggression Questionnaire (AQ and the Brown's Attention Deficit Disorder Scales (BADDS, provided a blood sample for erythrocyte fatty acid analysis using gas chromatography and the omega-3 index was calculated.The baseline omega-3 index ranged from 2.3% to 10.3%, indicating that some participants already had substantial omega-3 intake, however a median of 4.7% indicated a lower overall omega-3 intake than the general Australian population. Assessment of aggressive and attention deficit behaviour shows that there were negative correlations between baseline omega-3 index and baseline aggression categorisation scores (r = -0.21, P = 0.016; total AQ score (r = -0.234, P = 0.011; Anger (r = -0.222 p = 0.016; Hostility AQ (r = -0.239, P = 0.009; indirect aggression (r = -0.188 p = 0.042; total BADDS (r = -0.263, p = 0.005; Activation (r = -0.224, p = 0.016; Attention (r = -0.192, p = 0.043; Effort (r = -0.253, p = 0.007; Affect (r = -0.330, p = 0.000 and Memory (r = -0.240, p = 0.010.There is a high variability in omega-3 status of a NSW prison

  6. Search for lepton flavor violating decays tau to l \\omega (l = e, mu)

    Energy Technology Data Exchange (ETDEWEB)

    Collaboration, The BABAR; Aubert, B.

    2007-11-12

    A search for lepton flavor violating decays of a {tau} to a lighter-mass charged lepton and an {omega} vector meson is performed using 384.1 fb{sup -1} of e{sup +}e{sup -} annihilation data collected with the BABAR detector at the Stanford Linear Accelerator Center PEP-II storage ring. No signal is found, and the upper limits on the branching ratios are determined to be {beta}({tau}{sup {+-}} {yields} e{sup {+-}}{omega}) < 1.1 x 10{sup -7} and {beta}({tau}{sup {+-}} {yields} {mu}{sup {+-}}{omega}) < 1.0 x 10{sup -7} at 90% confidence level.

  7. Bioavailability of omega-3 long-chain polyunsaturated fatty acids from foods

    DEFF Research Database (Denmark)

    Mu, Huiling

    2008-01-01

    enriched with omega-3 LCPUFA can be good alternatives to improve the intake of these fatty acids. Effects of lipid structures and food matrices on bioavailability of omega-3 LCPUFA have been investigated. Short term studies showed that both lipid structure and food matrix affect the bioavailability......Increasing recognition of the importance of the omega-3 long chain polyunsaturated fatty acids (LCPUFA) has caused greater attention about dietary intake of these fatty acids. Fatty fish is the major dietary source of these fatty acids. Because of the low intake of fish at many places, foods...

  8. Handmade cloned transgenic sheep rich in omega-3 Fatty acids.

    Directory of Open Access Journals (Sweden)

    Peng Zhang

    Full Text Available Technology of somatic cell nuclear transfer (SCNT has been adapted worldwide to generate transgenic animals, although the traditional procedure relies largely on instrumental micromanipulation. In this study, we used the modified handmade cloning (HMC established in cattle and pig to produce transgenic sheep with elevated levels of omega-3 (n-3 fatty acids. Codon-optimized nematode mfat-1 was inserted into a eukaryotic expression vector and was transferred into the genome of primary ovine fibroblast cells from a male Chinese merino sheep. Reverse transcriptase PCR, gas chromatography, and chromosome analyses were performed to select nuclear donor cells capable of converting omega-6 (n-6 into n-3 fatty acids. Blastocysts developed after 7 days of in vitro culture were surgically transplanted into the uterus of female ovine recipients of a local sheep breed in Xinjiang. For the HMC, approximately 8.9% (n  =925 of reconstructed embryos developed to the blastocyst stage. Four recipients became pregnant after 53 blastocysts were transplanted into 29 naturally cycling females, and a total of 3 live transgenic lambs were produced. Detailed analyses on one of the transgenic lambs revealed a single integration of the modified nematode mfat-1 gene at sheep chromosome 5. The transgenic sheep expressed functional n-3 fatty acid desaturase, accompanied by more than 2-folds reduction of n-6/n-3 ratio in the muscle (p<0.01 and other major organs/tissues (p<0.05. To our knowledge, this is the first report of transgenic sheep produced by the HMC. Compared to the traditional SCNT method, HMC showed an equivalent efficiency but proved cheaper and easier in operation.

  9. Handmade Cloned Transgenic Sheep Rich in Omega-3 Fatty Acids

    Science.gov (United States)

    Dou, Hongwei; Chen, Lei; Chen, Longxin; Lin, Lin; Tan, Pingping; Vajta, Gabor; Gao, Jianfeng; Du, Yutao; Ma, Runlin Z.

    2013-01-01

    Technology of somatic cell nuclear transfer (SCNT) has been adapted worldwide to generate transgenic animals, although the traditional procedure relies largely on instrumental micromanipulation. In this study, we used the modified handmade cloning (HMC) established in cattle and pig to produce transgenic sheep with elevated levels of omega-3 (n−3) fatty acids. Codon-optimized nematode mfat-1 was inserted into a eukaryotic expression vector and was transferred into the genome of primary ovine fibroblast cells from a male Chinese merino sheep. Reverse transcriptase PCR, gas chromatography, and chromosome analyses were performed to select nuclear donor cells capable of converting omega-6 (n−6) into n−3 fatty acids. Blastocysts developed after 7 days of in vitro culture were surgically transplanted into the uterus of female ovine recipients of a local sheep breed in Xinjiang. For the HMC, approximately 8.9% (n  = 925) of reconstructed embryos developed to the blastocyst stage. Four recipients became pregnant after 53 blastocysts were transplanted into 29 naturally cycling females, and a total of 3 live transgenic lambs were produced. Detailed analyses on one of the transgenic lambs revealed a single integration of the modified nematode mfat-1 gene at sheep chromosome 5. The transgenic sheep expressed functional n−3 fatty acid desaturase, accompanied by more than 2-folds reduction of n−6/n−3 ratio in the muscle (p<0.01) and other major organs/tissues (p<0.05). To our knowledge, this is the first report of transgenic sheep produced by the HMC. Compared to the traditional SCNT method, HMC showed an equivalent efficiency but proved cheaper and easier in operation. PMID:23437077

  10. Oral omega-3 fatty acids promote resolution in chemical peritonitis.

    Science.gov (United States)

    Chacon, Alexander C; Phillips, Brett E; Chacon, Miranda A; Brunke-Reese, Deborah; Kelleher, Shannon L; Soybel, David I

    2016-11-01

    Recent studies suggest that purified omega-3 fatty acids may attenuate acute inflammation and hasten the transition to healing. In this study, we tested the hypothesis that pretreatment with omega-3-rich fish oil (FO) would promote resolution of peritoneal inflammation through production of specific lipid mediators. C57/BL6 mice were given a daily 200-μL oral gavage of saline (CTL) or FO (1.0-1.5 g/kg/d docosahexaenoic acid and 1.3-2.0 g/kg/d eicosapentaenoic acid) for 7 d before chemical peritonitis was induced with thioglycollate. Peritoneal lavage fluid was collected before induction and at days 2 and 4 after peritonitis onset. Prostaglandin E2 (PGE2), Leukotriene B4 (LTB4), Resolvin D1 (RvD1), and the composition of immune cell populations were examined in peritoneal lavage exudates. Cells harvested from the peritoneum were assessed for macrophage differentiation markers, phagocytosis, and lipopolysaccharide-induced cytokine secretion profiles (interleukin [IL]-6, IL-10, IL-1β, TNFα). The ratio of RvD1 to pro-inflammatory PGE2 and LTB4 was increased in the peritoneal cavity of FO-supplemented animals. FO induced a decrease in the number of monocytes in the lavage fluid, with no change in the number of macrophages, neutrophils, or lymphocytes. Macrophage phagocytosis and M1/M2 messenger RNA markers were unchanged by FO with the exception of decreased PPARγ expression. FO increased ex vivo TNFα secretion after stimulation with lipopolysaccharide. Our findings provide evidence that nutraceutically relevant doses of FO supplements given before and during chemical peritonitis shift the balance of lipid mediators towards a proresolution, anti-inflammatory state without drastically altering the number or phenotype of local innate immune cell populations. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Discrepancy between Knowledge and Perceptions of Dietary Omega-3 Fatty Acid Intake Compared with the Omega-3 Index

    Directory of Open Access Journals (Sweden)

    Sowmyanarayanan V. Thuppal

    2017-08-01

    Full Text Available Little is known about the relationship between perceptions of nutrient adequacy and biomarkers of nutrition status. This cross-sectional study of U.S. and German adults (n = 200; 18–80 years compared dietary practices, knowledge, and beliefs of omega-3 fatty acids (O3-FA with the omega-3 index (O3-I, an erythrocyte-based biomarker associated with cardiovascular disease (CVD risk. More than half of adults believed that O3-FAs are beneficial for heart and brain health and could correctly identify the food sources of O3-FA. However, the mean O3-I in the U.S. (4.3% and Germany (5.5% puts the majority of adults sampled (99% in intermediate or high CVD-risk categories. More Americans were considered at high CVD-risk (40% when compared with Germans (10%. In the U.S., but not Germany, women had a significantly higher O3-I than men (4.8% vs. 3.8%, p < 0.001. In the intermediate CVD-risk group, about one-third of adults in both countries (30% in the U.S. and 27% in Germany believed their diet was adequate in O3-FA. Notably, mean O3-I concentrations did not significantly differ with dietary perceptions of adequacy. More adults in Germany (26% than in the U.S. (10% believed that dietary supplements are needed to achieve a balanced diet. In spite of adequate knowledge about food sources and a consistent belief that O3-FA are important for health, very few participants had O3-I concentrations in the range for CVD protection.

  12. Induction of CD3 delta epsilon omega by phorbol 12-myristate 13-acetate

    DEFF Research Database (Denmark)

    Vangsted, A; Neisig, A; Wallin, H

    1993-01-01

    The effect of phorbol 12-myristate 13-acetate (PMA) on the synthesis, assembly and processing of the components of the T cell receptor (TcR) was studied with special focus on the CD3 omega chain. Treatment of the human leukemic T cell line Jurkat with PMA increased the synthesis of the Ti alpha, CD......3 gamma and CG3 zeta chains two- to threefold and the synthesis of Ti beta and CD3 delta epsilon omega complexes five- to sevenfold as assessed by metabolic labeling, immunoprecipitation and sodium dodecyl sulfate-polyacrylamide gel electrophoresis followed by scanning densitometry. The amount...... of TcR complexes expressed on the cell surface was decreased after 16 h of PMA treatment. Based on these results we propose a role of CD3 omega in retention of TcR complexes. From PMA-treated CEM cells more than 50-fold the amount of CD3 delta epsilon omega complexes was immunoprecipitated as compared...

  13. Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega

    National Research Council Canada - National Science Library

    Sievers, Fabian; Wilm, Andreas; Dineen, David; Gibson, Toby J; Karplus, Kevin; Li, Weizhong; Lopez, Rodrigo; McWilliam, Hamish; Remmert, Michael; Söding, Johannes; Thompson, Julie D; Higgins, Desmond G

    ...‐quality alignments, but scale badly with the number of sequences. In this paper, we describe a new program called Clustal Omega, which can align virtually any number of protein sequences quickly and that delivers accurate alignments...

  14. Omega-3 polyunsaturated fatty acid (fish oil) supplementation and the prevention of clinical cardiovascular disease

    Science.gov (United States)

    Multiple randomized controlled trials (RCTs) have assessed the effects of supplementation with eicosapentaenoic acid plus docosahexaenoic acid (omega-3 polyunsaturated fatty acids, commonly called fish oils) on the occurrence of clinical cardiovascular diseases. Although the effects of supplementati...

  15. Potential Role of Omega-3 Fatty Acids on the Myogenic Program of Satellite Cells

    Science.gov (United States)

    Bhullar, Amritpal S.; Putman, Charles T.; Mazurak, Vera C.

    2016-01-01

    Skeletal muscle loss is associated with aging as well as pathological conditions. Satellite cells (SCs) play an important role in muscle regeneration. Omega-3 fatty acids are widely studied in a variety of muscle wasting diseases; however, little is known about their impact on skeletal muscle regeneration. The aim of this review is to evaluate studies examining the effect of omega-3 fatty acids, α-linolenic acid, eicosapentaenoic acid, and docosahexaenoic acid on the regulation of SC proliferation and differentiation. This review highlights mechanisms by which omega-3 fatty acids may modulate the myogenic program of the stem cell population within skeletal muscles and identifies considerations for future studies. It is proposed that minimally three myogenic transcriptional regulatory factors, paired box 7 (Pax7), myogenic differentiation 1 protein, and myogenin, should be measured to confirm the stage of SCs within the myogenic program affected by omega-3 fatty acids. PMID:26884682

  16. Reduction of Heart Rate by Omega-3 Fatty Acids and the Potential Underlying Mechanisms

    Directory of Open Access Journals (Sweden)

    Jing Xuan Kang

    2012-10-01

    Full Text Available An elevated resting heart rate is one of the strongest predictors of cardiovascular mortality and is independently associated with sudden cardiac death (SCD. Agents capable of reducing heart rate without significant side effects are therefore of particular interest for the prevention of SCD. Recent human and animal studies have shown that omega-3 fatty acids can reduce heart rate. Our work has shown that omega-3 fatty acids significantly reduce membrane electrical excitability of the cardiac myocyte by lowering its resting membrane potential and the duration of the refractory period through inhibition of ion channels. We propose that these actions may be the underlying mechanisms for the omega-3 fatty acid-induced reduction of heart rate observed in both humans and animals. The heart rate-lowering capability of omega-3 fatty acids may contribute to their preventive effect against SCD.

  17. Omega-3 polyunsaturated fatty acids: a necessity for a comprehensive secondary prevention strategy

    Directory of Open Access Journals (Sweden)

    Jeetesh V Patel

    2009-09-01

    Full Text Available Jeetesh V Patel, Inessa Tracey, Elizabeth A Hughes, Gregory YH LipHaemostasis, Thrombosis and Vascular Biology Unit, University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, England, UKAbstract: Long-chain omega-3 polyunsaturated fatty acid (PUFA supplementation has been used for the secondary prevention of fatal and nonfatal myocardial infarction (MI. However, the benefit of this therapy is frequently confused with other established treatments in the therapeutic strategy among such patients. We review the data on omega-3 PUFA use in secondary care and consider indications for its use which include post-MI and raised triglycerides. We suggest that the available evidence supports the use of omega-3 supplementation as part of the comprehensive secondary care package for post-MI patients.Keywords: omega-3 polyunsaturated fatty acids, myocardial infarction

  18. Measurement of $\\omega$ meson parameters in $\\pi^{+}\\pi^{-}\\pi^{0}$ decay mode with CMD-2

    CERN Document Server

    Akhmetshin, R R; Aulchenko, V M; Banzarov, V S; Barkov, L M; Baru, S E; Bashtovoy, N S; Bondar, A E; Bondarev, D V; Chernyak, D V; Dhawan, S K; Eidelman, S I; Fedotovich, G V; Gabyshev, N I; Grebeniuk, A A; Grigoriev, D N; Hughes, V W; Khazin, B I; Koop, I A; Kurdadze, L M; Kuzmin, A S; Logashenko, I B; Lukin, P A; Lysenko, A P; Nesterenko, I N; Okhapkin, V S; Perevedentsev, E A; Polunin, A A; Purlatz, T A; Root, N I; Ruban, A A; Ryskulov, N M; Shamov, A G; Shatunov, Yu M; Shekhtman, A I; Sher, A E; Shwartz, B A; Sidorov, V A; Skrinsky, A N; Smakhtin, V P; Snopkov, I G; Solodov, E P; Stepanov, P Yu; Sukhanov, A Yu; Thompson, J A; Titov, V M; Valishev, A A; Yudin, Yu V; Zverev, S G

    2000-01-01

    About 11 200 $ e^+e^- \\to \\omega \\to \\pi^+\\pi^-\\pi^0$ events selected in the center of mass energy range from 760 to 810 MeV were used for the measurement of the $\\omega$ meson parameters. The following results have been obtained: $\\sigma _{0}=(1457 \\pm 23 \\pm 19 )$ nb, $m_{\\omega }=(782.71 \\pm 0.07 \\pm 0.04)$ MeV/c$^{2}$, $\\Gamma _{\\omega }=(8.68 \\pm 0.23 \\pm 0.10 )$ MeV, $\\Gamma _{e^+e^-}\\cdot$Br$(ømega \\to \\pi^+\\pi^-\\pi^0)= (0.528 \\pm 0.012 \\pm 0.007) \\cdot 10^{-3}$ MeV.

  19. Measurement of the $\\Xi_b^-$ and $\\Omega_b^-$ baryon lifetimes

    CERN Document Server

    Aaij, Roel; Adinolfi, Marco; Affolder, Anthony; Ajaltouni, Ziad; Albrecht, Johannes; Alessio, Federico; Alexander, Michael; Ali, Suvayu; Alkhazov, Georgy; Alvarez Cartelle, Paula; Alves Jr, Antonio; Amato, Sandra; Amerio, Silvia; Amhis, Yasmine; An, Liupan; Anderlini, Lucio; Anderson, Jonathan; Andreassen, Rolf; Andreotti, Mirco; Andrews, Jason; Appleby, Robert; Aquines Gutierrez, Osvaldo; Archilli, Flavio; Artamonov, Alexander; Artuso, Marina; Aslanides, Elie; Auriemma, Giulio; Baalouch, Marouen; Bachmann, Sebastian; Back, John; Badalov, Alexey; Balagura, Vladislav; Baldini, Wander; Barlow, Roger; Barschel, Colin; Barsuk, Sergey; Barter, William; Batozskaya, Varvara; Bauer, Thomas; Bay, Aurelio; Beddow, John; Bedeschi, Franco; Bediaga, Ignacio; Belogurov, Sergey; Belous, Konstantin; Belyaev, Ivan; Ben-Haim, Eli; Bencivenni, Giovanni; Benson, Sean; Benton, Jack; Berezhnoy, Alexander; Bernet, Roland; Bettler, Marc-Olivier; van Beuzekom, Martinus; Bien, Alexander; Bifani, Simone; Bird, Thomas; Bizzeti, Andrea; Bjørnstad, Pål Marius; Blake, Thomas; Blanc, Frédéric; Blouw, Johan; Blusk, Steven; Bocci, Valerio; Bondar, Alexander; Bondar, Nikolay; Bonivento, Walter; Borghi, Silvia; Borgia, Alessandra; Borsato, Martino; Bowcock, Themistocles; Bowen, Espen Eie; Bozzi, Concezio; Brambach, Tobias; van den Brand, Johannes; Bressieux, Joël; Brett, David; Britsch, Markward; Britton, Thomas; Brook, Nicholas; Brown, Henry; Bursche, Albert; Busetto, Giovanni; Buytaert, Jan; Cadeddu, Sandro; Calabrese, Roberto; Calvi, Marta; Calvo Gomez, Miriam; Camboni, Alessandro; Campana, Pierluigi; Campora Perez, Daniel; Carbone, Angelo; Carboni, Giovanni; Cardinale, Roberta; Cardini, Alessandro; Carranza-Mejia, Hector; Carson, Laurence; Carvalho Akiba, Kazuyoshi; Casse, Gianluigi; Cassina, Lorenzo; Castillo Garcia, Lucia; Cattaneo, Marco; Cauet, Christophe; Cenci, Riccardo; Charles, Matthew; Charpentier, Philippe; Cheung, Shu-Faye; Chiapolini, Nicola; Chrzaszcz, Marcin; Ciba, Krzystof; Cid Vidal, Xabier; Ciezarek, Gregory; Clarke, Peter; Clemencic, Marco; Cliff, Harry; Closier, Joel; Coco, Victor; Cogan, Julien; Cogneras, Eric; Collins, Paula; Comerma-Montells, Albert; Contu, Andrea; Cook, Andrew; Coombes, Matthew; Coquereau, Samuel; Corti, Gloria; Corvo, Marco; Counts, Ian; Couturier, Benjamin; Cowan, Greig; Craik, Daniel Charles; Cruz Torres, Melissa Maria; Cunliffe, Samuel; Currie, Robert; D'Ambrosio, Carmelo; Dalseno, Jeremy; David, Pascal; David, Pieter; Davis, Adam; De Bruyn, Kristof; De Capua, Stefano; De Cian, Michel; De Miranda, Jussara; De Paula, Leandro; De Silva, Weeraddana; De Simone, Patrizia; Decamp, Daniel; Deckenhoff, Mirko; Del Buono, Luigi; Déléage, Nicolas; Derkach, Denis; Deschamps, Olivier; Dettori, Francesco; Di Canto, Angelo; Dijkstra, Hans; Donleavy, Stephanie; Dordei, Francesca; Dorigo, Mirco; Dosil Suárez, Alvaro; Dossett, David; Dovbnya, Anatoliy; Dupertuis, Frederic; Durante, Paolo; Dzhelyadin, Rustem; Dziurda, Agnieszka; Dzyuba, Alexey; Easo, Sajan; Egede, Ulrik; Egorychev, Victor; Eidelman, Semen; Eisenhardt, Stephan; Eitschberger, Ulrich; Ekelhof, Robert; Eklund, Lars; El Rifai, Ibrahim; Elsasser, Christian; Esen, Sevda; Evans, Timothy; Falabella, Antonio; Färber, Christian; Farinelli, Chiara; Farley, Nathanael; Farry, Stephen; Ferguson, Dianne; Fernandez Albor, Victor; Ferreira Rodrigues, Fernando; Ferro-Luzzi, Massimiliano; Filippov, Sergey; Fiore, Marco; Fiorini, Massimiliano; Firlej, Miroslaw; Fitzpatrick, Conor; Fiutowski, Tomasz; Fontana, Marianna; Fontanelli, Flavio; Forty, Roger; Francisco, Oscar; Frank, Markus; Frei, Christoph; Frosini, Maddalena; Fu, Jinlin; Furfaro, Emiliano; Gallas Torreira, Abraham; Galli, Domenico; Gallorini, Stefano; Gambetta, Silvia; Gandelman, Miriam; Gandini, Paolo; Gao, Yuanning; Garofoli, Justin; Garra Tico, Jordi; Garrido, Lluis; Gaspar, Clara; Gauld, Rhorry; Gavardi, Laura; Gersabeck, Evelina; Gersabeck, Marco; Gershon, Timothy; Ghez, Philippe; Gianelle, Alessio; Giani', Sebastiana; Gibson, Valerie; Giubega, Lavinia-Helena; Gligorov, Vladimir; Göbel, Carla; Golubkov, Dmitry; Golutvin, Andrey; Gomes, Alvaro; Gordon, Hamish; Gotti, Claudio; Grabalosa Gándara, Marc; Graciani Diaz, Ricardo; Granado Cardoso, Luis Alberto; Graugés, Eugeni; Graziani, Giacomo; Grecu, Alexandru; Greening, Edward; Gregson, Sam; Griffith, Peter; Grillo, Lucia; Grünberg, Oliver; Gui, Bin; Gushchin, Evgeny; Guz, Yury; Gys, Thierry; Hadjivasiliou, Christos; Haefeli, Guido; Haen, Christophe; Haines, Susan; Hall, Samuel; Hamilton, Brian; Hampson, Thomas; Han, Xiaoxue; Hansmann-Menzemer, Stephanie; Harnew, Neville; Harnew, Samuel; Harrison, Jonathan; Hartmann, Thomas; He, Jibo; Head, Timothy; Heijne, Veerle; Hennessy, Karol; Henrard, Pierre; Henry, Louis; Hernando Morata, Jose Angel; van Herwijnen, Eric; Heß, Miriam; Hicheur, Adlène; Hill, Donal; Hoballah, Mostafa; Hombach, Christoph; Hulsbergen, Wouter; Hunt, Philip; Hussain, Nazim; Hutchcroft, David; Hynds, Daniel; Idzik, Marek; Ilten, Philip; Jacobsson, Richard; Jaeger, Andreas; Jalocha, Pawel; Jans, Eddy; Jaton, Pierre; Jawahery, Abolhassan; Jezabek, Marek; Jing, Fanfan; John, Malcolm; Johnson, Daniel; Jones, Christopher; Joram, Christian; Jost, Beat; Jurik, Nathan; Kaballo, Michael; Kandybei, Sergii; Kanso, Walaa; Karacson, Matthias; Karbach, Moritz; Kelsey, Matthew; Kenyon, Ian; Ketel, Tjeerd; Khanji, Basem; Khurewathanakul, Chitsanu; Klaver, Suzanne; Kochebina, Olga; Kolpin, Michael; Komarov, Ilya; Koopman, Rose; Koppenburg, Patrick; Korolev, Mikhail; Kozlinskiy, Alexandr; Kravchuk, Leonid; Kreplin, Katharina; Kreps, Michal; Krocker, Georg; Krokovny, Pavel; Kruse, Florian; Kucharczyk, Marcin; Kudryavtsev, Vasily; Kurek, Krzysztof; Kvaratskheliya, Tengiz; La Thi, Viet Nga; Lacarrere, Daniel; Lafferty, George; Lai, Adriano; Lambert, Dean; Lambert, Robert W; Lanciotti, Elisa; Lanfranchi, Gaia; Langenbruch, Christoph; Langhans, Benedikt; Latham, Thomas; Lazzeroni, Cristina; Le Gac, Renaud; van Leerdam, Jeroen; Lees, Jean-Pierre; Lefèvre, Regis; Leflat, Alexander; Lefrançois, Jacques; Leo, Sabato; Leroy, Olivier; Lesiak, Tadeusz; Leverington, Blake; Li, Yiming; Liles, Myfanwy; Lindner, Rolf; Linn, Christian; Lionetto, Federica; Liu, Bo; Liu, Guoming; Lohn, Stefan; Longstaff, Iain; Lopes, Jose; Lopez-March, Neus; Lowdon, Peter; Lu, Haiting; Lucchesi, Donatella; Luo, Haofei; Lupato, Anna; Luppi, Eleonora; Lupton, Oliver; Machefert, Frederic; Machikhiliyan, Irina V; Maciuc, Florin; Maev, Oleg; Malde, Sneha; Manca, Giulia; Mancinelli, Giampiero; Manzali, Matteo; Maratas, Jan; Marchand, Jean François; Marconi, Umberto; Marin Benito, Carla; Marino, Pietro; Märki, Raphael; Marks, Jörg; Martellotti, Giuseppe; Martens, Aurelien; Martín Sánchez, Alexandra; Martinelli, Maurizio; Martinez Santos, Diego; Martinez Vidal, Fernando; Martins Tostes, Danielle; Massafferri, André; Matev, Rosen; Mathe, Zoltan; Matteuzzi, Clara; Mazurov, Alexander; McCann, Michael; McCarthy, James; McNab, Andrew; McNulty, Ronan; McSkelly, Ben; Meadows, Brian; Meier, Frank; Meissner, Marco; Merk, Marcel; Milanes, Diego Alejandro; Minard, Marie-Noelle; Moggi, Niccolò; Molina Rodriguez, Josue; Monteil, Stephane; Moran, Dermot; Morandin, Mauro; Morawski, Piotr; Mordà, Alessandro; Morello, Michael Joseph; Moron, Jakub; Mountain, Raymond; Muheim, Franz; Müller, Katharina; Muresan, Raluca; Mussini, Manuel; Muster, Bastien; Naik, Paras; Nakada, Tatsuya; Nandakumar, Raja; Nasteva, Irina; Needham, Matthew; Neri, Nicola; Neubert, Sebastian; Neufeld, Niko; Neuner, Max; Nguyen, Anh Duc; Nguyen, Thi-Dung; Nguyen-Mau, Chung; Nicol, Michelle; Niess, Valentin; Niet, Ramon; Nikitin, Nikolay; Nikodem, Thomas; Novoselov, Alexey; Oblakowska-Mucha, Agnieszka; Obraztsov, Vladimir; Oggero, Serena; Ogilvy, Stephen; Okhrimenko, Oleksandr; Oldeman, Rudolf; Onderwater, Gerco; Orlandea, Marius; Otalora Goicochea, Juan Martin; Owen, Patrick; Oyanguren, Maria Arantza; Pal, Bilas Kanti; Palano, Antimo; Palombo, Fernando; Palutan, Matteo; Panman, Jacob; Papanestis, Antonios; Pappagallo, Marco; Parkes, Christopher; Parkinson, Christopher John; Passaleva, Giovanni; Patel, Girish; Patel, Mitesh; Patrignani, Claudia; Pazos Alvarez, Antonio; Pearce, Alex; Pellegrino, Antonio; Pepe Altarelli, Monica; Perazzini, Stefano; Perez Trigo, Eliseo; Perret, Pascal; Perrin-Terrin, Mathieu; Pescatore, Luca; Pesen, Erhan; Petridis, Konstantin; Petrolini, Alessandro; Picatoste Olloqui, Eduardo; Pietrzyk, Boleslaw; Pilař, Tomas; Pinci, Davide; Pistone, Alessandro; Playfer, Stephen; Plo Casasus, Maximo; Polci, Francesco; Poluektov, Anton; Polycarpo, Erica; Popov, Alexander; Popov, Dmitry; Popovici, Bogdan; Potterat, Cédric; Powell, Andrew; Prisciandaro, Jessica; Pritchard, Adrian; Prouve, Claire; Pugatch, Valery; Puig Navarro, Albert; Punzi, Giovanni; Qian, Wenbin; Rachwal, Bartolomiej; Rademacker, Jonas; Rakotomiaramanana, Barinjaka; Rama, Matteo; Rangel, Murilo; Raniuk, Iurii; Rauschmayr, Nathalie; Raven, Gerhard; Reichert, Stefanie; Reid, Matthew; dos Reis, Alberto; Ricciardi, Stefania; Richards, Alexander; Rihl, Mariana; Rinnert, Kurt; Rives Molina, Vincente; Roa Romero, Diego; Robbe, Patrick; Rodrigues, Ana Barbara; Rodrigues, Eduardo; Rodriguez Perez, Pablo; Roiser, Stefan; Romanovsky, Vladimir; Romero Vidal, Antonio; Rotondo, Marcello; Rouvinet, Julien; Ruf, Thomas; Ruffini, Fabrizio; Ruiz, Hugo; Ruiz Valls, Pablo; Sabatino, Giovanni; Saborido Silva, Juan Jose; Sagidova, Naylya; Sail, Paul; Saitta, Biagio; Salustino Guimaraes, Valdir; Sanchez Mayordomo, Carlos; Sanmartin Sedes, Brais; Santacesaria, Roberta; Santamarina Rios, Cibran; Santovetti, Emanuele; Sapunov, Matvey; Sarti, Alessio; Satriano, Celestina; Satta, Alessia; Savrie, Mauro; Savrina, Darya; Schiller, Manuel; Schindler, Heinrich; Schlupp, Maximilian; Schmelling, Michael; Schmidt, Burkhard; Schneider, Olivier; Schopper, Andreas; Schune, Marie Helene; Schwemmer, Rainer; Sciascia, Barbara; Sciubba, Adalberto; Seco, Marcos; Semennikov, Alexander; Senderowska, Katarzyna; Sepp, Indrek; Serra, Nicola; Serrano, Justine; Sestini, Lorenzo; Seyfert, Paul; Shapkin, Mikhail; Shapoval, Illya; Shcheglov, Yury; Shears, Tara; Shekhtman, Lev; Shevchenko, Vladimir; Shires, Alexander; Silva Coutinho, Rafael; Simi, Gabriele; Sirendi, Marek; Skidmore, Nicola; Skwarnicki, Tomasz; Smith, Anthony; Smith, Edmund; Smith, Eluned; Smith, Jackson; Smith, Mark; Snoek, Hella; Sokoloff, Michael; Soler, Paul; Soomro, Fatima; Souza, Daniel; Souza De Paula, Bruno; Spaan, Bernhard; Sparkes, Ailsa; Spinella, Franco; Spradlin, Patrick; Stagni, Federico; Stahl, Sascha; Steinkamp, Olaf; Stenyakin, Oleg; Stevenson, Scott; Stoica, Sabin; Stone, Sheldon; Storaci, Barbara; Stracka, Simone; Straticiuc, Mihai; Straumann, Ulrich; Stroili, Roberto; Subbiah, Vijay Kartik; Sun, Liang; Sutcliffe, William; Swientek, Krzysztof; Swientek, Stefan; Syropoulos, Vasileios; Szczekowski, Marek; Szczypka, Paul; Szilard, Daniela; Szumlak, Tomasz; T'Jampens, Stephane; Teklishyn, Maksym; Tellarini, Giulia; Teubert, Frederic; Thomas, Christopher; Thomas, Eric; van Tilburg, Jeroen; Tisserand, Vincent; Tobin, Mark; Tolk, Siim; Tomassetti, Luca; Tonelli, Diego; Topp-Joergensen, Stig; Torr, Nicholas; Tournefier, Edwige; Tourneur, Stephane; Tran, Minh Tâm; Tresch, Marco; Tsaregorodtsev, Andrei; Tsopelas, Panagiotis; Tuning, Niels; Ubeda Garcia, Mario; Ukleja, Artur; Ustyuzhanin, Andrey; Uwer, Ulrich; Vagnoni, Vincenzo; Valenti, Giovanni; Vallier, Alexis; Vazquez Gomez, Ricardo; Vazquez Regueiro, Pablo; Vázquez Sierra, Carlos; Vecchi, Stefania; Velthuis, Jaap; Veltri, Michele; Veneziano, Giovanni; Vesterinen, Mika; Viaud, Benoit; Vieira, Daniel; Vieites Diaz, Maria; Vilasis-Cardona, Xavier; Vollhardt, Achim; Volyanskyy, Dmytro; Voong, David; Vorobyev, Alexey; Vorobyev, Vitaly; Voß, Christian; Voss, Helge; de Vries, Jacco; Waldi, Roland; Wallace, Charlotte; Wallace, Ronan; Walsh, John; Wandernoth, Sebastian; Wang, Jianchun; Ward, David; Watson, Nigel; Websdale, David; Whitehead, Mark; Wicht, Jean; Wiedner, Dirk; Wilkinson, Guy; Williams, Matthew; Williams, Mike; Wilson, Fergus; Wimberley, Jack; Wishahi, Julian; Wislicki, Wojciech; Witek, Mariusz; Wormser, Guy; Wotton, Stephen; Wright, Simon; Wu, Suzhi; Wyllie, Kenneth; Xie, Yuehong; Xing, Zhou; Xu, Zhirui; Yang, Zhenwei; Yuan, Xuhao; Yushchenko, Oleg; Zangoli, Maria; Zavertyaev, Mikhail; Zhang, Feng; Zhang, Liming; Zhang, Wen Chao; Zhang, Yanxi; Zhelezov, Alexey; Zhokhov, Anatoly; Zhong, Liang; Zvyagin, Alexander

    2014-01-01

    Using a data sample of pp collisions corresponding to an integrated luminosity of $3~ \\rm fb^{-1}$, the $\\Xi_b^-$ and $\\Omega_b^-$ baryons are reconstructed in the $\\Xi_b^- \\rightarrow J/\\psi \\Xi^-$ and $\\Omega_b^- \\rightarrow J/\\psi \\Omega^-$ decay modes and their lifetimes measured to be $\\tau (\\Xi_b^-) = 1.55\\, ^{+0.10}_{-0.09}~{\\rm(stat)} \\pm 0.03\\,{\\rm(syst)}$ ps, $\\tau (\\Omega_b^-) = 1.54\\, ^{+0.26}_{-0.21}~{\\rm(stat)} \\pm 0.05\\,{\\rm(syst)}$ ps. These are the most precise determinations to date. Both measurements are in good agreement with previous experimental results and with theoretical predictions.

  20. On the errors on Omega(0): Monte Carlo simulations of the EMSS cluster sample

    DEFF Research Database (Denmark)

    Oukbir, J.; Arnaud, M.

    2001-01-01

    and normalization of the power spectrum of matter fluctuations imply relatively large uncertainties on this estimate of Omega (0), of the order of Delta (stat)Omega (0) = 0.1 at the 1 sigma level. On the other hand, the statistical uncertainties due to the finite size of the high-redshift sample are twice as small...... the scatter around the relation between cluster X-ray luminosity and temperature to be a source of systematic error, of the order of Delta (syst)Omega (0) = 0.09, if not properly taken into account in the modelling. After correcting for this bias, our best Omega (0) is 0.66. The uncertainties on the shape...

  1. Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid?

    Directory of Open Access Journals (Sweden)

    Sieswerda Lee E

    2007-09-01

    Full Text Available Abstract Background A growing number of observational and epidemiological studies have suggested that mental illness, in particular mood disorders, is associated with reduced dietary intake and/or cellular abundance of omega-3 polyunsaturated fatty acids (PUFA. This has prompted researchers to test the efficacy of omega-3 PUFA in a range of different psychiatric disorders. We have critically reviewed the double blind placebo controlled clinical trials published prior to April 2007 to determine whether omega-3 PUFA are likely to be efficacious in these disorders. Results Most trials involved a small number of participants but were largely well designed. Omega-3 PUFA were well tolerated by both children and adults with mild gastrointestinal effects being the only consistently reported adverse event. For schizophrenia and borderline personality disorder we found little evidence of a robust clinically relevant effect. In the case of attention deficit hyperactivity disorder and related disorders, most trials showed at most small benefits over placebo. A limited meta-analysis of these trials suggested that benefits of omega-3 PUFA supplementation may be greater in a classroom setting than at home. Some evidence indicates that omega-3 PUFA may reduce symptoms of anxiety although the data is preliminary and inconclusive. The most convincing evidence for beneficial effects of omega-3 PUFA is to be found in mood disorders. A meta-analysis of trials involving patients with major depressive disorder and bipolar disorder provided evidence that omega-3 PUFA supplementation reduces symptoms of depression. Furthermore, meta-regression analysis suggests that supplementation with eicosapentaenoic acid may be more beneficial in mood disorders than with docosahexaenoic acid, although several confounding factors prevented a definitive conclusion being made regarding which species of omega-3 PUFA is most beneficial. The mechanisms underlying the apparent efficacy of

  2. Efficacy and Safety of Omega-3/6 Fatty Acids, Methylphenidate, and a Combined Treatment in Children With ADHD.

    Science.gov (United States)

    Barragán, Eduardo; Breuer, Dieter; Döpfner, Manfred

    2017-03-01

    To compare efficacy of Omega-3/6 fatty acids (Equazen eye q™) with methylphenidate (MPH) and combined MPH + Omega-3/6 in children with ADHD. Participants ( N = 90) were randomized to Omega-3/6, long-acting MPH, or combination for 12 months. ADHD symptoms were assessed using the ADHD Rating Scale and Clinical Global Impressions-Severity (CGI-S) scale. ADHD symptoms decreased in all treatment arms. Although significant differences favoring Omega + MPH over Omega-3/6 alone were found for ADHD Total and Hyperactivity-Impulsivity subscales, results on the Inattention subscale were similar. CGI-S scores decreased slowly and consistently with Omega-3/6, compared with a rapid decrease and subsequent slight increase in the MPH-containing arms. Adverse events were numerically less frequent with Omega-3/6 or MPH + Omega-3/6 than MPH alone. The tested combination of Omega-3/6 fatty acids had similar effects to MPH, whereas the MPH + Omega combination appeared to have some tolerability benefits over MPH.

  3. Supplementation with Omega-3 Fatty Acids in Psychiatric Disorders: A Review of Literature Data

    Directory of Open Access Journals (Sweden)

    Paola Bozzatello

    2016-07-01

    Full Text Available A new application for omega-3 fatty acids has recently emerged, concerning the treatment of several mental disorders. This indication is supported by data of neurobiological research, as highly unsaturated fatty acids (HUFAs are highly concentrated in neural phospholipids and are important components of the neuronal cell membrane. They modulate the mechanisms of brain cell signaling, including the dopaminergic and serotonergic pathways. The aim of this review is to provide a complete and updated account of the empirical evidence of the efficacy and safety that are currently available for omega-3 fatty acids in the treatment of psychiatric disorders. The main evidence for the effectiveness of eicosapentaenoic acid (EPA and docosahexaenoic acid (DHA has been obtained in mood disorders, in particular in the treatment of depressive symptoms in unipolar and bipolar depression. There is some evidence to support the use of omega-3 fatty acids in the treatment of conditions characterized by a high level of impulsivity and aggression and borderline personality disorders. In patients with attention deficit hyperactivity disorder, small-to-modest effects of omega-3 HUFAs have been found. The most promising results have been reported by studies using high doses of EPA or the association of omega-3 and omega-6 fatty acids. In schizophrenia, current data are not conclusive and do not allow us either to refuse or support the indication of omega-3 fatty acids. For the remaining psychiatric disturbances, including autism spectrum disorders, anxiety disorders, obsessive-compulsive disorder, eating disorders and substance use disorder, the data are too scarce to draw any conclusion. Concerning tolerability, several studies concluded that omega-3 can be considered safe and well tolerated at doses up to 5 g/day.

  4. The effect of Omega 3 fatty acid on the lipid profile of hemodialysis patient

    OpenAIRE

    O. Taziki; M. Lesan Pezeshki

    2005-01-01

    Coronary heart diseases (CHD) are the main cause of mortality in hemodialysis patients. Lipid profile abnormality in hemodialysis patients including hypertriglyceridemia , normal total cholesterol, modest decline in HDL rise in LDL are effected by omega 3 speculative. The purpose of this study was to investigate the effects of omega 3 fatty acid on lipid profile in hemodialysis patients. this clinical trial was performed on 16 hemodialysis patients with hypertriglyceridemia. They were asked t...

  5. Omega-3 Fatty Acids for Major Depressive Disorder: A Systematic Review

    Science.gov (United States)

    2015-01-01

    Bennett, 1999). 5-HIAA is a metabolite of serotonin , the neurotransmitter thought to be most closely associated with depression . Subsequently...Omega-3 Fatty Acids for Major Depressive Disorder A Systematic Review Sydne Newberry, Susanne Hempel, Marika Booth, Brett Ewing, Alicia Ruelaz...00-2015 to 00-00-2015 4. TITLE AND SUBTITLE Omega-3 Fatty Acids for Major Depressive Disorder: A Systematic Review 5a. CONTRACT NUMBER 5b

  6. Omega-3 fatty acids' supplementation in Alzheimer's disease: A systematic review.

    Science.gov (United States)

    Canhada, Scheine; Castro, Kamila; Perry, Ingrid Schweigert; Luft, Vivian Cristine

    2017-05-03

    Alzheimer's disease (AD) is a neurodegeneration disorder characterized by progressive impairments of memory, language, reasoning, and other cognitive functions. Evidence suggests that omega-3 fatty acids may act as a possible protection factor in AD