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Sample records for achieves functional analysis

  1. Egalitarianism and Achievement in the Involvement of Others in Consumer Decisions: A Functional Analysis.

    Science.gov (United States)

    Miller, Duane I.

    1980-01-01

    Studied how egalitaranism and success through individual achievement, were expressed in the involvement of others in consumer decisions. Results found egalitarians involved others in seeking more information. Individual achievement subjects delegated more decision responsibility for non-ego involving decisions. Suggests involvement of others could…

  2. Achievement Goals and Achievement Emotions: A Meta-Analysis

    Science.gov (United States)

    Huang, Chiungjung

    2011-01-01

    This meta-analysis synthesized 93 independent samples (N = 30,003) in 77 studies that reported in 78 articles examining correlations between achievement goals and achievement emotions. Achievement goals were meaningfully associated with different achievement emotions. The correlations of mastery and mastery approach goals with positive achievement…

  3. Positive Functions of Emotions in Achievement Sports

    Science.gov (United States)

    Puig, Nuria; Vilanova, Anna

    2011-01-01

    This article presents the results of two research projects on the emotions of men engaged in achievement outdoor sports. The conditions were analyzed under which emotions carry out positive functions. The question strikes us as a fundamental one, because it is of crucial importance when it comes to increasing sportspeople's success. The…

  4. Disentangling the Circularity in Sen's Capability Approach: An Analysis of the Co-Evolution of Functioning Achievement and Resources

    Science.gov (United States)

    Binder, Martin; Coad, Alex

    2011-01-01

    There is an ambiguity in Amartya Sen's capability approach as to what constitutes an individual's resources, conversion factors and valuable functionings. What we here call the "circularity problem" points to the fact that all three concepts seem to be mutually endogenous and interdependent. To econometrically account for this…

  5. Functional analysis

    CERN Document Server

    Kantorovich, L V

    1982-01-01

    Functional Analysis examines trends in functional analysis as a mathematical discipline and the ever-increasing role played by its techniques in applications. The theory of topological vector spaces is emphasized, along with the applications of functional analysis to applied analysis. Some topics of functional analysis connected with applications to mathematical economics and control theory are also discussed. Comprised of 18 chapters, this book begins with an introduction to the elements of the theory of topological spaces, the theory of metric spaces, and the theory of abstract measure space

  6. Positive functions of emotions in achievement sports.

    Science.gov (United States)

    Puig, Núria; Vilanova, Anna

    2011-06-01

    This article presents the results of two research projects on the emotions of men engaged in achievement outdoor sports. The conditions were analyzed under which emotions carry out positive functions. The question strikes us as a fundamental one, because it is of crucial importance when it comes to increasing sportspeople's success. The theoretical framework applied was that of microfunctionalism. The method, of a qualitative nature, was based on in-depth interviews, each lasting between 1.5 and 2 hr with a total of 14 sportspersons. The results show that in order for emotions to fulfill positive functions, three conditions must be met: (a) existence of passion, which, with its dialectical character of pleasure and suffering underlies all the other emotions and acts as a motor that pushes the sportsperson forward, despite all the contretemps he might meet on the way; (b) intense emotion work, which may be conducted only if accompanied by knowledge and experience of the natural environment acquired over the years; and (c) conciliation between emotion work and the feeling rules characteristic of each sport subculture. For those individuals who pursue achievement in outdoor sports, these results will provide more concrete indications regarding how to carry out the emotional preparation required for these sports.

  7. Recent Achievement in Gene Cloning and Functional Genomics in Soybean

    Directory of Open Access Journals (Sweden)

    Zhengjun Xia

    2013-01-01

    Full Text Available Soybean is a model plant for photoperiodism as well as for symbiotic nitrogen fixation. However, a rather low efficiency in soybean transformation hampers functional analysis of genes isolated from soybean. In comparison, rapid development and progress in flowering time and photoperiodic response have been achieved in Arabidopsis and rice. As the soybean genomic information has been released since 2008, gene cloning and functional genomic studies have been revived as indicated by successfully characterizing genes involved in maturity and nematode resistance. Here, we review some major achievements in the cloning of some important genes and some specific features at genetic or genomic levels revealed by the analysis of functional genomics of soybean.

  8. [Self-esteem, family function, and school achievement of adolescents].

    Science.gov (United States)

    Gutiérrez-Saldaña, Pedro; Camacho-Calderón, Nicolás; Martínez-Martínez, Martha L

    2007-11-01

    To determine the relationship between academic achievement, self-esteem and family function in adolescents. Descriptive, cross-sectional study. State secondary school in Querétaro state, Mexico. Seventy-four adolescents of both sexes between the ages of 10 and 17, enrolled in a state secondary school. Two groups of 37 pupils were formed, chosen by simple randomized sampling according to high or low academic achievement. Participants were clinically healthy and prior informed consent for their participation was obtained. Self-esteem based on self-concept format A, family function based on FACES III and academic achievement based on the school evaluation scale. A descriptive statistical analysis and the chi2 test were used (P self-esteem, 68% (P = .00007; OR, 7.55; 95% CI, 2.39-24.84); a functional family, 54% (P = .011); were mainly female, 73% (P = .018); age, 13 (60%) (P = .062); school in the morning, 95% (P = .000); and were in second grade, 46% (P = .026). Pupils with low academic achievement had low self-esteem, 78% (P = .00007; OR, 7.55; 95% CI, 2.39-24.84); came from borderline-function families, 43% (P = .47); were male, 54% (P = .018; OR, 3.18; 95% CI, 1.08-9.48); age 13, 38% (P = .062); in afternoon school, 76% (P = .00); and were in first grade, 43% (P = .144). Upon establishing a relationship between academic achievement and family dynamics, it was found that family dysfunction is a risk factor (OR, 6.67; 95% CI, 1.42-34). Low self-esteem and family dysfunction are risk factors for low academic achievement.

  9. Effects of Achieving Target Measures in Rheumatoid Arthritis on Functional Status, Quality of Life, and Resource Utilization: Analysis of Clinical Practice Data

    Science.gov (United States)

    Joo, Seongjung; Kawabata, Hugh; Al, Maiwenn J.; Allison, Paul D.; Rutten‐van Mölken, Maureen P. M. H.; Frits, Michelle L.; Iannaccone, Christine K.; Shadick, Nancy A.; Weinblatt, Michael E.

    2016-01-01

    Objective To evaluate associations between achieving guideline‐recommended targets of disease activity, defined by the Disease Activity Score in 28 joints using C‐reactive protein level (DAS28‐CRP) control for intraclass correlation and estimate effects of independent variables on outcomes of the modified Health Assessment Questionnaire (M‐HAQ), the EuroQol 5‐domain (EQ‐5D; a quality‐of‐life measure), hospitalization, and durable medical equipment (DME) use, we employed mixed models for continuous outcomes and generalized estimating equations for binary outcomes. Results Among 1,297 subjects, achievement (versus nonachievement) of recommended disease targets was associated with enhanced physical functioning and lower health resource utilization. After controlling for baseline covariates, achievement of disease targets (versus LDA) was associated with significantly enhanced physical functioning based on SDAI ≤3.3 (ΔM‐HAQ −0.047; P = 0.0100) and CDAI ≤2.8 (−0.073; P = 0.0003) but not DAS28‐CRP <2.6 (−0.022; P = 0.1735). Target attainment was associated with significantly improved EQ‐5D (0.022–0.096; P < 0.0030 versus LDA, MDA, or SDA). Patients achieving guideline‐recommended disease targets were 36–45% less likely to be hospitalized (P < 0.0500) and 23–45% less likely to utilize DME (P < 0.0100). Conclusion Attaining recommended target disease‐activity measures was associated with enhanced physical functioning and health‐related quality of life. Some health outcomes were similar in subjects attaining guideline targets versus LDA. Achieving LDA is a worthy clinical objective in some patients. PMID:26238974

  10. Nonlinear functional analysis

    Directory of Open Access Journals (Sweden)

    W. L. Fouché

    1983-03-01

    Full Text Available In this article we discuss some aspects of nonlinear functional analysis. It included reviews of Banach’s contraction theorem, Schauder’s fixed point theorem, globalising techniques and applications of homotopy theory to nonlinear functional analysis. The author emphasises that fundamentally new ideas are required in order to achieve a better understanding of phenomena which contain both nonlinear and definite infinite dimensional features.

  11. Functional analysis

    CERN Document Server

    Kesavan, S

    2009-01-01

    The material presented in this book is suited for a first course in Functional Analysis which can be followed by Masters students. While covering all the standard material expected of such a course, efforts have been made to illustrate the use of various theorems via examples taken from differential equations and the calculus of variations, either through brief sections or through exercises. In fact, this book will be particularly useful for students who would like to pursue a research career in the applications of mathematics. The book includes a chapter on weak and weak topologies and their applications to the notions of reflexivity, separability and uniform convexity. The chapter on the Lebesgue spaces also presents the theory of one of the simplest classes of Sobolev spaces. The book includes a chapter on compact operators and the spectral theory for compact self-adjoint operators on a Hilbert space. Each chapter has large collection of exercises at the end. These illustrate the results of the text, show ...

  12. Direct and indirect influences of executive functions on mathematics achievement.

    Science.gov (United States)

    Cragg, Lucy; Keeble, Sarah; Richardson, Sophie; Roome, Hannah E; Gilmore, Camilla

    2017-02-08

    Achievement in mathematics is predicted by an individual's domain-specific factual knowledge, procedural skill and conceptual understanding as well as domain-general executive function skills. In this study we investigated the extent to which executive function skills contribute to these three components of mathematical knowledge, whether this mediates the relationship between executive functions and overall mathematics achievement, and if these relationships change with age. Two hundred and ninety-three participants aged between 8 and 25years completed a large battery of mathematics and executive function tests. Domain-specific skills partially mediated the relationship between executive functions and mathematics achievement: Inhibitory control within the numerical domain was associated with factual knowledge and procedural skill, which in turn was associated with mathematical achievement. Working memory contributed to mathematics achievement indirectly through factual knowledge, procedural skill and, to a lesser extent, conceptual understanding. There remained a substantial direct pathway between working memory and mathematics achievement however, which may reflect the role of working memory in identifying and constructing problem representations. These relationships were remarkably stable from 8years through to young adulthood. Our findings help to refine existing multi-component frameworks of mathematics and understand the mechanisms by which executive functions support mathematics achievement.

  13. Mirror Analysis: How To Achieve Customer-Driven Human Performance.

    Science.gov (United States)

    Mourier, Pierre

    1999-01-01

    Presents an evaluation/development method for achieving customer-driven improvement in organizations. Describes the steps to external and internal "mirror analysis," a process for determining if the organization functions as a mirror of customers' needs and expectations. Twelve figures illustrate factors in the process. (AEF)

  14. Preschool executive functioning abilities predict early mathematics achievement.

    Science.gov (United States)

    Clark, Caron A C; Pritchard, Verena E; Woodward, Lianne J

    2010-09-01

    Impairments in executive function have been documented in school-age children with mathematical learning difficulties. However, the utility and specificity of preschool executive function abilities in predicting later mathematical achievement are poorly understood. This study examined linkages between children's developing executive function abilities at age 4 and children's subsequent achievement in mathematics at age 6, 1 year after school entry. The study sample consisted of a regionally representative cohort of 104 children followed prospectively from ages 2 to 6 years. At age 4, children completed a battery of executive function tasks that assessed planning, set shifting, and inhibitory control. Teachers completed the preschool version of the Behavior Rating Inventory of Executive Function. Clinical and classroom measures of children's mathematical achievement were collected at age 6. Results showed that children's performance on set shifting, inhibitory control, and general executive behavior measures during the preschool period accounted for substantial variability in children's early mathematical achievement at school. These associations persisted even after individual differences in general cognitive ability and reading achievement were taken into account. Findings suggest that early measures of executive function may be useful in identifying children who may experience difficulties learning mathematical skills and concepts. They also suggest that the scaffolding of these executive skills could potentially be a useful additional component in early mathematics education.

  15. Diet models with linear goal programming: impact of achievement functions

    NARCIS (Netherlands)

    Gerdessen, J.C.; Vries, de J.H.M.

    2015-01-01

    Background/Objectives: Diet models based on goal programming (GP) are valuable tools in designing diets that comply with nutritional, palatability and cost constraints. Results derived from GP models are usually very sensitive to the type of achievement function that is chosen. This paper aims to pr

  16. Children's Effortful Control and Academic Achievement: Mediation through Social Functioning

    Science.gov (United States)

    Valiente, Carlos; Eisenberg, Nancy; Haugen, Rg; Spinrad, Tracy L.; Hofer, Claire; Liew, Jeffrey; Kupfer, Anne

    2011-01-01

    Research Findings: The purpose of this study was to test the premise that children's effortful control (EC) is prospectively related to their academic achievement and to specify mechanisms through which EC is related to academic success. We used data from 214 children (M age at Time 1 [T1] = 73 months) to test whether social functioning (e.g.,…

  17. Poverty and Educational Achievement: An Analysis Plan.

    Science.gov (United States)

    Zill, Nicholas

    This paper describes a series of proposed analyses that would make use of existing information from national surveys of the school-aged population and other large-scale databases in order to illuminate trends in the makeup, life circumstances, schooling, and educational achievement of the population of United States children that is eligible for…

  18. Schooling, educational achievement, and cognitive functioning among young Guatemalan adults.

    Science.gov (United States)

    Stein, Aryeh D; Behrman, Jere R; DiGirolamo, Ann; Grajeda, Rubén; Martorell, Reynaldo; Quisumbing, Agnes; Ramakrishnan, Usha

    2005-06-01

    Quantity and quality of schooling obtained and the resulting skills and knowledge acquired are important components of human capital. We describe the distribution of selected measures of schooling, educational achievement, and cognitive functioning among individuals who participated as children in a nutrition supplementation trial in Guatemala and were followed up in 2002-04. Among 1,469 respondents (response rate 80%), who were 26-41 years of age in 2003, more than 90% of men and women had attended at least some school; more than half of men and more than one-third of women had completed sixth grade. Schooling attainment of both men and women has increased across birth cohorts but the schooling gap between men and women has increased. Parental socioeconomic status, as measured in 1975, is a strong predictor of schooling attainment. Basic literacy is high among those studied, with more than 80% able to read simple sentences. The gap in educational achievement favoring men narrowed across birth cohorts due to increases among younger women. The greater performance among men on the Raven's Progressive Matrices test persisted despite increased scores in the younger birth cohorts for both men and women. Migrants to Guatemala City have completed more years of school and scored higher on the tests of educational achievement and cognitive functioning than have cohort members who have remained in the study villages.

  19. RTPP Analysis Results: Achievements and Challenges

    Science.gov (United States)

    Agrotis, Loukis; Alfaro Sanz, Pedro; Svehla, Drazen; Dow, John; Zandbergen, Rene

    2010-05-01

    One of the key objectives of the IGS Real Time Pilot Project is the establishment of an experimental IGS Real Time Clock Service comprising individual Analysis Centre (AC) solutions and the investigation of strategies for generating a Real Time combination product. The latter is intended to provide a stable, reliable and high quality GNSS product. Currently there are 4 ACs (BKG, DLR, ESA and NRCan) generating individual real time products, and a fifth (GMV) that is producing a product based on one-hour predictions. This paper will cover the evolution in the accuracies of the individual solutions and will show the impact that the participation in the RTPP has had on the ACs, serving not only as an external benchmark, but also as a discussion forum that has prompted their continued evolution and improvement. In its role as RTPP AC coordinator, ESOC has been computing and disseminating a daily combination clock product since July 2008, based on daily submissions of clock RINEX and SP3 orbit files by the individual ACs. This exercise has helped to develop and validate the combination techniques and the RTPP products are stored at the CDDIS, IGN and KASI data centres with the designation "igt". The current satellite clock quality, of better than 0.2 ns RMS compared to the IGS rapids, comfortably exceeds the initial RTPP goal of 0.5 ns and gives a high confidence on the implemented method. ESOC is currently working on the implementation of a Real Time combination product, from RTCM orbit and clock streams received in real time via BKG's NTRIP system. This service is expected to be ready in the March-April timeframe and be operational by mid 2010. As well as discussing the status and evolution of the Real Time products, this paper will also focus on specific problems and challenges in the Real Time processing. For example, it has been found that GPS Block IIA satellites exhibit occasional glitches, where most receivers loose lock simultaneously. These events cause clock

  20. 2 x 2 Achievement Goals and Achievement Emotions: A Cluster Analysis of Students' Motivation

    Science.gov (United States)

    Jang, Leong Yeok; Liu, Woon Chia

    2012-01-01

    This study sought to better understand the adoption of multiple achievement goals at an intra-individual level, and its links to emotional well-being, learning, and academic achievement. Participants were 480 Secondary Two students (aged between 13 and 14 years) from two coeducational government schools. Hierarchical cluster analysis revealed the…

  1. 2 x 2 Achievement Goals and Achievement Emotions: A Cluster Analysis of Students' Motivation

    Science.gov (United States)

    Jang, Leong Yeok; Liu, Woon Chia

    2012-01-01

    This study sought to better understand the adoption of multiple achievement goals at an intra-individual level, and its links to emotional well-being, learning, and academic achievement. Participants were 480 Secondary Two students (aged between 13 and 14 years) from two coeducational government schools. Hierarchical cluster analysis revealed the…

  2. Do Women's Orgasms Function as a Masculinity Achievement for Men?

    Science.gov (United States)

    Chadwick, Sara B; van Anders, Sari M

    2017-02-23

    Orgasms have been promoted as symbols of sexual fulfillment for women, and have perhaps become the symbol of a woman's healthy sex life. However, some research has suggested that this focus on women's orgasms, though ostensibly for women, may actually serve men; but the mechanisms of this are unclear. In the present experiment, we hypothesized that women's orgasms specifically function as a masculinity achievement for men. To test this, we randomly assigned 810 men (M age = 25.44, SD = 8.31) to read a vignette where they imagined that an attractive woman either did or did not orgasm during a sexual encounter with them. Participants then rated their sexual esteem and the extent to which they would feel masculine after experiencing the given situation. Our results showed that men felt more masculine and reported higher sexual esteem when they imagined that a woman orgasmed during sexual encounters with them, and that this effect was exacerbated for men with high masculine gender role stress. These results suggest that women's orgasms do function-at least in part-as a masculinity achievement for men.

  3. Creativity and Academic Achievement: A Meta-Analysis

    Science.gov (United States)

    Gajda, Aleksandra; Karwowski, Maciej; Beghetto, Ronald A.

    2017-01-01

    This article reports on a meta-analysis of 120 studies (total N = 52,578; 782 effects) examining the relationship between creativity and academic achievement in research conducted since the 1960s. Average correlation between creativity and academic achievement was r = 0.22, 95% CI [0.19, 0.24]. An analysis of moderators revealed that this…

  4. Comprehensive School Reform and Student Achievement: A Meta-Analysis.

    Science.gov (United States)

    Borman, Geoffrey D.; Hewes, Gina M.; Overman, Laura T.; Brown, Shelly

    Using 232 studies, this meta analysis reviewed the research on the achievement effects of the nationally disseminated and externally developed school improvement programs known as "whole-school" or "comprehensive" reforms. In addition to reviewing the overall achievement effects of comprehensive school reform (CSR), the meta analysis considered…

  5. Creativity and Academic Achievement: A Meta-Analysis

    Science.gov (United States)

    Gajda, Aleksandra; Karwowski, Maciej; Beghetto, Ronald A.

    2017-01-01

    This article reports on a meta-analysis of 120 studies (total N = 52,578; 782 effects) examining the relationship between creativity and academic achievement in research conducted since the 1960s. Average correlation between creativity and academic achievement was r = 0.22, 95% CI [0.19, 0.24]. An analysis of moderators revealed that this…

  6. Specific early number skills mediate the association between executive functioning skills and mathematics achievement.

    Science.gov (United States)

    Fuhs, Mary Wagner; Hornburg, Caroline Byrd; McNeil, Nicole M

    2016-08-01

    A growing literature reports significant associations between children's executive functioning skills and their mathematics achievement. The purpose of this study was to examine if specific early number skills, such as quantity discrimination, number line estimation, number sets identification, fast counting, and number word comprehension, mediate this association. In 141 kindergarteners, cross-sectional analyses controlling for IQ revealed that number sets identification (but not the other early number skills) mediated the association between executive functioning skills and mathematics achievement. A longitudinal analysis showed that higher executive functioning skills predicted higher number sets identification in kindergarten, which in turn predicted growth in mathematics achievement from kindergarten to second grade. Results suggest that executive functioning skills may help children quickly and accurately identify number sets as wholes instead of getting distracted by the individual components of the sets, and this focus on sets, in turn, may help children learn more advanced mathematics concepts in the early elementary grades. (PsycINFO Database Record

  7. Mathematics Achievement as a Function of within- and between-School Differences

    Science.gov (United States)

    Mohammadpour, Ebrahim; Abdul Ghafar, Mohamed Najib

    2014-01-01

    Achievement in mathematics of eighth-grade students is modeled as a function of within-school, between-school and cross-country differences. The data were obtained from 217,728 students, within 7,216 secondary schools, in 48 countries, who participated in the 2007 Trends in International Mathematics and Science Study. Multilevel analysis showed…

  8. Fundamentals of Functional Analysis

    CERN Document Server

    Kutateladze, S S; Slovák, Jan

    2001-01-01

    A concise guide to basic sections of modern functional analysis. Included are such topics as the principles of Banach and Hilbert spaces, the theory of multinormed and uniform spaces, the Riesz-Dunford holomorphic functional calculus, the Fredholm index theory, convex analysis and duality theory for locally convex spaces with applications to the Schwartz spaces of distributions and Radon measures.

  9. Functional data analysis

    CERN Document Server

    Ramsay, J O

    1997-01-01

    Scientists today collect samples of curves and other functional observations. This monograph presents many ideas and techniques for such data. Included are expressions in the functional domain of such classics as linear regression, principal components analysis, linear modelling, and canonical correlation analysis, as well as specifically functional techniques such as curve registration and principal differential analysis. Data arising in real applications are used throughout for both motivation and illustration, showing how functional approaches allow us to see new things, especially by exploiting the smoothness of the processes generating the data. The data sets exemplify the wide scope of functional data analysis; they are drwan from growth analysis, meterology, biomechanics, equine science, economics, and medicine. The book presents novel statistical technology while keeping the mathematical level widely accessible. It is designed to appeal to students, to applied data analysts, and to experienced researc...

  10. Fundamentals of functional analysis

    CERN Document Server

    Farenick, Douglas

    2016-01-01

    This book provides a unique path for graduate or advanced undergraduate students to begin studying the rich subject of functional analysis with fewer prerequisites than is normally required. The text begins with a self-contained and highly efficient introduction to topology and measure theory, which focuses on the essential notions required for the study of functional analysis, and which are often buried within full-length overviews of the subjects. This is particularly useful for those in applied mathematics, engineering, or physics who need to have a firm grasp of functional analysis, but not necessarily some of the more abstruse aspects of topology and measure theory normally encountered. The reader is assumed to only have knowledge of basic real analysis, complex analysis, and algebra. The latter part of the text provides an outstanding treatment of Banach space theory and operator theory, covering topics not usually found together in other books on functional analysis. Written in a clear, concise manner,...

  11. Lectures on Functional Analysis

    CERN Document Server

    Kurepa, Svetozar; Kraljević, Hrvoje

    1987-01-01

    This volume consists of a long monographic paper by J. Hoffmann-Jorgensen and a number of shorter research papers and survey articles covering different aspects of functional analysis and its application to probability theory and differential equations.

  12. Applied functional analysis

    CERN Document Server

    Griffel, DH

    2002-01-01

    A stimulating introductory text, this volume examines many important applications of functional analysis to mechanics, fluid mechanics, diffusive growth, and approximation. Detailed enough to impart a thorough understanding, the text is also sufficiently straightforward for those unfamiliar with abstract analysis. Its four-part treatment begins with distribution theory and discussions of Green's functions. Essentially independent of the preceding material, the second and third parts deal with Banach spaces, Hilbert space, spectral theory, and variational techniques. The final part outlines the

  13. An Analysis of High School Mathematics Achievement and English Language Arts Achievement as Predictors of Science Achievement

    Science.gov (United States)

    Edwards, Anthony C.

    2012-01-01

    Science assessments require students to read and comprehend questions and to solve mathematical problems. The purpose of this study is to determine whether the following variables can be used to predict science achievement: English language arts achievement, mathematics achievement, socioeconomic status (SES), limited English proficiency (LEP)…

  14. An Analysis of High School Mathematics Achievement and English Language Arts Achievement as Predictors of Science Achievement

    Science.gov (United States)

    Edwards, Anthony C.

    2012-01-01

    Science assessments require students to read and comprehend questions and to solve mathematical problems. The purpose of this study is to determine whether the following variables can be used to predict science achievement: English language arts achievement, mathematics achievement, socioeconomic status (SES), limited English proficiency (LEP)…

  15. Functional Object Analysis

    DEFF Research Database (Denmark)

    Raket, Lars Lau

    -effect formulations, where the observed functional signal is assumed to consist of both fixed and random functional effects. This thesis takes the initial steps toward the development of likelihood-based methodology for functional objects. We first consider analysis of functional data defined on high......-dimensional Euclidean spaces under the effect of additive spatially correlated effects, and then move on to consider how to include data alignment in the statistical model as a nonlinear effect under additive correlated noise. In both cases, we will give directions on how to generalize the methodology to more complex...

  16. Attitudes and Achievement in Statistics: A Meta-Analysis Study

    Science.gov (United States)

    Emmioglu, Esma; Capa-Aydin, Yesim

    2012-01-01

    This study examined the relationships among statistics achievement and four components of attitudes toward statistics (Cognitive Competence, Affect, Value, and Difficulty) as assessed by the SATS. Meta-analysis results revealed that the size of relationships differed by the geographical region in which the studies were conducted as well as by the…

  17. An Analysis of Alternative School Effectiveness on Student Achievement

    Science.gov (United States)

    Moger, Scott Douglas

    2010-01-01

    This study is a comparative analysis investigating student achievement, attendance rates, grade point average and credit earned by at-risk students attending an alternative high school of choice, at-risk students attending a traditional high school and at-risk students attending a Disciplinary Alternative Education Placement Campus within the same…

  18. Transport energy consumption achievement based on indicator analysis

    Science.gov (United States)

    Jiang, Jian

    2017-06-01

    In order to evaluate the transport sustainability level for regions, the concept of achievement efficiency in transport energy consumption is initially suggested in this paper. The research object is not only for the energy consumption by transport operation but also the whole life of the transport procedure, which is the thought of life cycle assessment. And then, on the quantitative analysis to calculate the transport energy achievement efficiency of the regions, the indicators that can represent the achievement of transport energy consumption are convincingly found out by indicator theory. Next, concentration is focused on the transport related indicators and proper indicators are picked up from the candidate indicators, which were the affecting factors to this issue. After that, using the selected indicators, we introduce the method of data envelopment analysis to do quantitative analysis, which helps to get the achievement efficiency of transport energy among cities all over the world. The analysis result shows the efficient regions and the inefficient regions respectively. Furthermore, the detailed efficiency value of each region is also laid out clearly. For the improvement, the inadequate output or input variables of the inefficient regions were listed compared with the efficient regions so that corresponding transport policy implications can be resulted for the inefficient regions to reach high level sustainability.

  19. Attitudes and Achievement in Statistics: A Meta-Analysis Study

    Science.gov (United States)

    Emmioglu, Esma; Capa-Aydin, Yesim

    2012-01-01

    This study examined the relationships among statistics achievement and four components of attitudes toward statistics (Cognitive Competence, Affect, Value, and Difficulty) as assessed by the SATS. Meta-analysis results revealed that the size of relationships differed by the geographical region in which the studies were conducted as well as by the…

  20. Applied functional analysis

    CERN Document Server

    Oden, J Tinsley

    2010-01-01

    The textbook is designed to drive a crash course for beginning graduate students majoring in something besides mathematics, introducing mathematical foundations that lead to classical results in functional analysis. More specifically, Oden and Demkowicz want to prepare students to learn the variational theory of partial differential equations, distributions, and Sobolev spaces and numerical analysis with an emphasis on finite element methods. The 1996 first edition has been used in a rather intensive two-semester course. -Book News, June 2010

  1. Achieving the Gaussian Rate-Distortion Function by Prediction

    CERN Document Server

    Zamir, Ram; Erez, Uri

    2007-01-01

    The "water-filling" solution for the quadratic rate-distortion function of a stationary Gaussian source is given in terms of its power spectrum. This formula naturally lends itself to a frequency domain "test-channel" realization. We provide an alternative time-domain realization for the rate-distortion function, based on linear prediction. This solution has some interesting implications, including the optimality at all distortion levels of pre/post filtered vector-quantized differential pulse code modulation (DPCM), and a duality relationship with decision-feedback equalization (DFE) for inter-symbol interference (ISI) channels.

  2. FY 1998 achievement report on the R and D project on industrial science technology. Development of a functional biomolecule analysis/synthesis system; 1998 nendo kinosei seitai bunshi kaiseki gosei system no kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    For the purpose of developing the technology required for the biotechnology industry, a study was made on proteins having ligand recognition function, and the FY 1998 results were reported. In the technology development of a system for various/diversified syntheses of functional molecules, a system was designed/trially manufactured which enables the simultaneous synthesis of various biological/functional substances (compound library) at high-efficiency. In the development of the structure analysis system of ligand recognized proteins, a high-efficient biopolymer analysis system was developed which is based on TOF (time-of-flight) mass spectrometer and analyzes proteins produced by recombined genes quickly and precisely. In the R and D of functional molecules using ligand recognized proteins, the cloning was successfully made of the human estrogen receptor gene hER {alpha}, which is composed of 1,785 bp, from MCF-7-BOS. Further, the bioassay system for estrogen-like substances using MCF-7 cells was established. (NEDO)

  3. Discrete Hadamard transformation algorithm's parallelism analysis and achievement

    Science.gov (United States)

    Hu, Hui

    2009-07-01

    With respect to Discrete Hadamard Transformation (DHT) wide application in real-time signal processing while limitation in operation speed of DSP. The article makes DHT parallel research and its parallel performance analysis. Based on multiprocessor platform-TMS320C80 programming structure, the research is carried out to achieve two kinds of parallel DHT algorithms. Several experiments demonstrated the effectiveness of the proposed algorithms.

  4. Notes on functional analysis

    CERN Document Server

    Bhatia, Rajendra

    2009-01-01

    These notes are a record of a one semester course on Functional Analysis given by the author to second year Master of Statistics students at the Indian Statistical Institute, New Delhi. Students taking this course have a strong background in real analysis, linear algebra, measure theory and probability, and the course proceeds rapidly from the definition of a normed linear space to the spectral theorem for bounded selfadjoint operators in a Hilbert space. The book is organised as twenty six lectures, each corresponding to a ninety minute class session. This may be helpful to teachers planning a course on this topic. Well prepared students can read it on their own.

  5. A Mediation Analysis of Achievement Motives, Goals, Learning Strategies, and Academic Achievement

    Science.gov (United States)

    Diseth, Age; Kobbeltvedt, Therese

    2010-01-01

    Background: Previous research is inconclusive regarding antecedents and consequences of achievement goals, and there is a need for more research in order to examine the joint effects of different types of motives and learning strategies as predictors of academic achievement. Aims: To investigate the relationship between achievement motives,…

  6. Muscle function in avian flight: achieving power and control

    Science.gov (United States)

    Biewener, Andrew A.

    2011-01-01

    Flapping flight places strenuous requirements on the physiological performance of an animal. Bird flight muscles, particularly at smaller body sizes, generally contract at high frequencies and do substantial work in order to produce the aerodynamic power needed to support the animal's weight in the air and to overcome drag. This is in contrast to terrestrial locomotion, which offers mechanisms for minimizing energy losses associated with body movement combined with elastic energy savings to reduce the skeletal muscles' work requirements. Muscles also produce substantial power during swimming, but this is mainly to overcome body drag rather than to support the animal's weight. Here, I review the function and architecture of key flight muscles related to how these muscles contribute to producing the power required for flapping flight, how the muscles are recruited to control wing motion and how they are used in manoeuvring. An emergent property of the primary flight muscles, consistent with their need to produce considerable work by moving the wings through large excursions during each wing stroke, is that the pectoralis and supracoracoideus muscles shorten over a large fraction of their resting fibre length (33–42%). Both muscles are activated while being lengthened or undergoing nearly isometric force development, enhancing the work they perform during subsequent shortening. Two smaller muscles, the triceps and biceps, operate over a smaller range of contractile strains (12–23%), reflecting their role in controlling wing shape through elbow flexion and extension. Remarkably, pigeons adjust their wing stroke plane mainly via changes in whole-body pitch during take-off and landing, relative to level flight, allowing their wing muscles to operate with little change in activation timing, strain magnitude and pattern. PMID:21502121

  7. Nonlinear functional analysis

    CERN Document Server

    Deimling, Klaus

    1985-01-01

    topics. However, only a modest preliminary knowledge is needed. In the first chapter, where we introduce an important topological concept, the so-called topological degree for continuous maps from subsets ofRn into Rn, you need not know anything about functional analysis. Starting with Chapter 2, where infinite dimensions first appear, one should be familiar with the essential step of consider­ ing a sequence or a function of some sort as a point in the corresponding vector space of all such sequences or functions, whenever this abstraction is worthwhile. One should also work out the things which are proved in § 7 and accept certain basic principles of linear functional analysis quoted there for easier references, until they are applied in later chapters. In other words, even the 'completely linear' sections which we have included for your convenience serve only as a vehicle for progress in nonlinearity. Another point that makes the text introductory is the use of an essentially uniform mathematical languag...

  8. Achievements and open issues in the determination of polarized parton distribution functions

    CERN Document Server

    Nocera, Emanuele R

    2015-01-01

    I review the current status of the determination of helicity-dependent, or polarized, parton distribution functions from a comprehensive analysis of experimental data in perturbative quantum chromodynamics. I illustrate the latest achievements driven by new measurements in polarized proton-proton collisions at the Relativistic Heavy Ion Collider, namely the first evidence of a sizable polarized light sea quark asymmetry and of a positive polarized gluon distribution in the proton. I discuss which are the open issues in the determination of polarized distributions, and how these may be addressed in the future by ongoing, planned and proposed experimental programs.

  9. The Effect of Executive Function on Science Achievement Among Normally Developing 10-Year Olds

    Science.gov (United States)

    Lederman, Sheri G.

    Executive function (EF) is an umbrella term used to identify a set of discrete but interrelated cognitive abilities that enable individuals to engage in goal-directed, future-oriented action in response to a novel context. Developmental studies indicate that EF is predictive of reading and math achievement in middle childhood. The purpose of this study was to identify the association between EF and science achievement among normally developing 10 year olds. A sample of fifth grade students from a Northeastern suburban community participated in tests of EF, science, and intelligence. Consistent with adult models of EF, principal components analysis identified a three-factor model of EF organization in middle childhood, including cognitive flexibility, working memory, and inhibition. Multiple regression analyses revealed that executive function processes of cognitive flexibility, working memory, and inhibition were all predictive of science performance. Post hoc analyses revealed that high-performing science students differed significantly from low-performing students in both cognitive flexibility and working memory. These findings suggest that complex academic demands specific to science achievement rely on the emergence and maturation of EF components.

  10. Using Survival Analysis to Describe Developmental Achievements of Early Intervention Recipients at Kindergarten

    Science.gov (United States)

    Scarborough, Anita A.; Hebbeler, Kathleen M.; Spiker, Donna; Simeonsson, Rune J.

    2011-01-01

    Survival analysis was used to document the developmental achievements of 2298 kindergarten children who participated in the National Early Intervention Longitudinal Study, a study that followed children from entry to Part C early intervention (EI) through kindergarten. Survival functions were produced depicting the percentage of children at…

  11. Physical activity and obesity mediate the association between childhood motor function and adolescents’ academic achievement

    OpenAIRE

    Kantomaa, Marko T.; Stamatakis, Emmanuel; Kankaanpää, Anna; Kaakinen, Marika; Rodriguez, Alina; Taanila, Anja; Ahonen, Timo; Järvelin, Marjo-Riitta; Tammelin, Tuija

    2012-01-01

    The global epidemic of obesity and physical inactivity may have detrimental implications for young people’s cognitive function and academic achievement. This prospective study investigated whether childhood motor function predicts later academic achievement via physical activity, fitness, and obesity. The study sample included 8,061 children from the Northern Finland Birth Cohort 1986, which contains data about parent-reported motor function at age 8 y and self-reported physical activity, pre...

  12. Modern psychometrics for assessing achievement goal orientation: a Rasch analysis.

    Science.gov (United States)

    Muis, Krista R; Winne, Philip H; Edwards, Ordene V

    2009-09-01

    A program of research is needed that assesses the psychometric properties of instruments designed to quantify students' achievement goal orientations to clarify inconsistencies across previous studies and to provide a stronger basis for future research. We conducted traditional psychometric and modern Rasch-model analyses of the Achievement Goals Questionnaire (AGQ, Elliot & McGregor, 2001) and the Patterns of Adaptive Learning Scale (PALS, Midgley et al., 2000) to provide an in-depth analysis of the two most popular instruments in educational psychology. For Study 1, 217 undergraduate students enrolled in educational psychology courses participated. Thirty-four were male and 181 were female (two did not respond). Participants completed the AGQ in the context of their educational psychology class. For Study 2, 126 undergraduate students enrolled in educational psychology courses participated. Thirty were male and 95 were female (one did not respond). Participants completed the PALS in the context of their educational psychology class. Traditional psychometric assessments of the AGQ and PALS replicated previous studies. For both, reliability estimates ranged from good to very good for raw subscale scores and fit for the models of goal orientations were good. Based on traditional psychometrics, the AGQ and PALS are valid and reliable indicators of achievement goals. Rasch analyses revealed that estimates of reliability for items were very good but respondent ability estimates varied from poor to good for both the AGQ and PALS. These findings indicate that items validly and reliably reflect a group's aggregate goal orientation, but using either instrument to characterize an individual's goal orientation is hazardous.

  13. Key elements on team achievement: a retrospective analysis.

    Science.gov (United States)

    Taveira, Alvaro D

    2008-07-01

    This study is a historical reconstruction and in-depth scrutiny of one very successful team initiative within a Quality Improvement (QI) program in a municipal government organization. The identification of the essential concepts that contributed to the team's success and their integration into a local explanatory theory of team achievement is the final purpose of the study. The focus of this retrospective study is on the team process, with primary attention given to team members' perspectives and reflections on the project development. Data collection and analysis were conducted with methods drawn from the qualitative research tradition and from Quality Management. Main findings point to the importance of consistent management support, correct team composition with an emphasis on the team leader choice and demeanor, and to the central role of training in the group conduct. The negotiated approach to decision-making employed by the team, which reflected its organizational context, and the effort and mechanisms that allowed the group to reach equilibrium between internal and external interests proved critical for its ultimate achievement.

  14. A Primer on Functional Analysis

    Science.gov (United States)

    Yoman, Jerome

    2008-01-01

    This article presents principles and basic steps for practitioners to complete a functional analysis of client behavior. The emphasis is on application of functional analysis to adult mental health clients. The article includes a detailed flow chart containing all major functional diagnoses and behavioral interventions, with functional assessment…

  15. Clinical Characteristics of Rheumatoid Arthritis Patients Achieving Functional Remission with Six Months of Biological DMARDs Treatment.

    Science.gov (United States)

    Miwa, Yusuke; Takahashi, Ryo; Ikari, Yuzo; Maeoka, Airi; Nishimi, Shinichiro; Oguro, Nao; Hayashi, Tomoki; Hatano, Mika; Isojima, Sakiko; Yanai, Ryo; Kasama, Tsuyoshi; Toyoshima, Yoichi; Inagaki, Katsunori; Sanada, Kenji

    2017-01-01

    Objective Although previous studies have reported the prognostic factors for functional remission, no reports have cited the predictive factors. Our aim was to study the predictive factors for functional remission, which is a treatment goal in rheumatoid arthritis (RA), after receiving biological disease-modifying antirheumatic drugs (bDMARDs) treatment for six months. Methods The study consisted of 333 RA patients treated with bDMARDs for six months. The following patient characteristics were investigated: age, gender, disease duration, type of bDMARDs, baseline steroid and methotrexate dosage, and levels of serum rheumatoid factor, matrix metalloprotease, anti-cyclic citrullinated peptides antibody, tumor necrosis factor-α, and interleukin-6. In our evaluation, we used the Simplified Disease Activity Index (SDAI) for RA disease activity, health assessment questionnaire disability index (HAQ-DI) for activity of daily living, Short Form (SF)-36 for quality of life, and Hamilton Depression Rating Scale (HAM-D) or Self-rating Depression Scale (SDS) to determine the patients' depression status. The subjects were divided into two groups: patients with HAQ-DI≤0.5 and HAQ-DI>0.5 at 6 months. Results A univariate analysis comparing a group of RA patients without functional remission (n=68) showed that the patients with functional remission (n=164) had the following in common compared with those without remission: younger age, shorter disease duration, lower baseline steroid dosage, lower SDAI, lower HAQ-DI, higher SF-36, and lower HAM-D. Only lower HAQ-DI scores and "mental health" score on the SF-36 were detected using a logistic regression analysis. Conclusion These findings suggested that RA patients with lower HAQ-DI and lower depression scores at baseline were more likely to achieve functional remission using bDMARDs treatment than those without these variables.

  16. Physical activity and obesity mediate the association between childhood motor function and adolescents’ academic achievement

    Science.gov (United States)

    Kantomaa, Marko T.; Stamatakis, Emmanuel; Kankaanpää, Anna; Kaakinen, Marika; Rodriguez, Alina; Taanila, Anja; Ahonen, Timo; Järvelin, Marjo-Riitta; Tammelin, Tuija

    2013-01-01

    The global epidemic of obesity and physical inactivity may have detrimental implications for young people’s cognitive function and academic achievement. This prospective study investigated whether childhood motor function predicts later academic achievement via physical activity, fitness, and obesity. The study sample included 8,061 children from the Northern Finland Birth Cohort 1986, which contains data about parent-reported motor function at age 8 y and self-reported physical activity, predicted cardiorespiratory fitness (cycle ergometer test), obesity (body weight and height), and academic achievement (grades) at age 16 y. Structural equation models with unstandardized (B) and standardized (β) coefficients were used to test whether, and to what extent, physical activity, cardiorespiratory fitness, and obesity at age 16 mediated the association between childhood motor function and adolescents’ academic achievement. Physical activity was associated with a higher grade-point average, and obesity was associated with a lower grade-point average in adolescence. Furthermore, compromised motor function in childhood had a negative indirect effect on adolescents’ academic achievement via physical inactivity (B = –0.023, 95% confidence interval = –0.031, –0.015) and obesity (B = –0.025, 95% confidence interval = –0.039, –0.011), but not via cardiorespiratory fitness. These results suggest that physical activity and obesity may mediate the association between childhood motor function and adolescents’ academic achievement. Compromised motor function in childhood may represent an important factor driving the effects of obesity and physical inactivity on academic underachievement. PMID:23277558

  17. Physical activity and obesity mediate the association between childhood motor function and adolescents' academic achievement.

    Science.gov (United States)

    Kantomaa, Marko T; Stamatakis, Emmanuel; Kankaanpää, Anna; Kaakinen, Marika; Rodriguez, Alina; Taanila, Anja; Ahonen, Timo; Järvelin, Marjo-Riitta; Tammelin, Tuija

    2013-01-29

    The global epidemic of obesity and physical inactivity may have detrimental implications for young people's cognitive function and academic achievement. This prospective study investigated whether childhood motor function predicts later academic achievement via physical activity, fitness, and obesity. The study sample included 8,061 children from the Northern Finland Birth Cohort 1986, which contains data about parent-reported motor function at age 8 y and self-reported physical activity, predicted cardiorespiratory fitness (cycle ergometer test), obesity (body weight and height), and academic achievement (grades) at age 16 y. Structural equation models with unstandardized (B) and standardized (β) coefficients were used to test whether, and to what extent, physical activity, cardiorespiratory fitness, and obesity at age 16 mediated the association between childhood motor function and adolescents' academic achievement. Physical activity was associated with a higher grade-point average, and obesity was associated with a lower grade-point average in adolescence. Furthermore, compromised motor function in childhood had a negative indirect effect on adolescents' academic achievement via physical inactivity (B = -0.023, 95% confidence interval = -0.031, -0.015) and obesity (B = -0.025, 95% confidence interval = -0.039, -0.011), but not via cardiorespiratory fitness. These results suggest that physical activity and obesity may mediate the association between childhood motor function and adolescents' academic achievement. Compromised motor function in childhood may represent an important factor driving the effects of obesity and physical inactivity on academic underachievement.

  18. Executive Function as a Mediator between SES and Academic Achievement throughout Childhood

    Science.gov (United States)

    Lawson, Gwendolyn M.; Farah, Martha J.

    2017-01-01

    Childhood socioeconomic status (SES), as measured by parental education and family income, is highly predictive of academic achievement, but little is known about how specific cognitive systems shape SES disparities in achievement outcomes. This study investigated the extent to which executive function (EF) mediated associations between parental…

  19. Relations among Executive Function, Number Sense, and Mathematics Achievement in Kindergartners

    Science.gov (United States)

    Irwin, Casey Marie

    2013-01-01

    Early number sense knowledge is highly predictive of later math achievement (Herbers et al., in press; Jordan, Kaplan, Ramineni, & Locuniak, 2009; Obradovic i et al., 2009). However, research suggests that variables beyond number competencies contribute to students' mathematics achievement, most notably, executive function (Blair & Razza,…

  20. Relations among Executive Function, Number Sense, and Mathematics Achievement in Kindergartners

    Science.gov (United States)

    Irwin, Casey Marie

    2013-01-01

    Early number sense knowledge is highly predictive of later math achievement (Herbers et al., in press; Jordan, Kaplan, Ramineni, & Locuniak, 2009; Obradovic i et al., 2009). However, research suggests that variables beyond number competencies contribute to students' mathematics achievement, most notably, executive function (Blair & Razza,…

  1. Executive Function as a Mediator between SES and Academic Achievement throughout Childhood

    Science.gov (United States)

    Lawson, Gwendolyn M.; Farah, Martha J.

    2017-01-01

    Childhood socioeconomic status (SES), as measured by parental education and family income, is highly predictive of academic achievement, but little is known about how specific cognitive systems shape SES disparities in achievement outcomes. This study investigated the extent to which executive function (EF) mediated associations between parental…

  2. Chronic sleep reduction, functioning at school and school achievement in preadolescents

    NARCIS (Netherlands)

    Meijer, A.M.

    2008-01-01

    This study investigates the relationship between chronic sleep reduction, functioning at school and school achievement of boys and girls. To establish individual consequences of chronic sleep reduction (tiredness, sleepiness, loss of energy and emotional instability) the Chronic Sleep Reduction Ques

  3. Chronic sleep reduction, functioning at school and school achievement in preadolescents

    NARCIS (Netherlands)

    Meijer, A.M.

    2008-01-01

    This study investigates the relationship between chronic sleep reduction, functioning at school and school achievement of boys and girls. To establish individual consequences of chronic sleep reduction (tiredness, sleepiness, loss of energy and emotional instability) the Chronic Sleep Reduction

  4. Study of academic achievements using spatial analysis tools

    Science.gov (United States)

    González, C.; Velilla, C.; Sánchez-Girón, V.

    2012-04-01

    In the 2010/12 academic year the College of Agricultural Engineering of the Technical University of Madrid implemented three new degrees all of them adapted to the European Space for Higher Education. These degrees are namely: Graduate in Agricultural Engineering and Science, Graduate in Food Engineering and Graduate in Agro-Environmental Engineering. A total of 382 new incoming students were finally registered and a survey study was carried out with these students about their academic achievement with the aim of finding the level of dependence among the following variables: the final mark in their secondary studies, the option followed in the secondary studies (Art, Science and Technology, and Humanities and Social Sciences), the mark obtained in the entering examination to the university and in which of the two opportunities per year this examination takes place the latter mark was obtained. Similarly, another group of 77 students were evaluated independently to the former group. These students were those entering the College in the previous academic year (2009/10) and decided to change their curricula to the new ones. Subsequently, using the tools of spatial analysis of geographic information systems, we analyzed the possible relationship between the success or failure at school and the socioeconomic profile of new students in a grade. For this purpose every student was referenced assigning UTM coordinates to their postal addresses. Furthermore, all students' secondary schools were geographically coded considering their typology (public, private, and private subsidized) and fares. Each student was represented by its average geometric point in order to be correlated to their respective record. Following this procedure a map of the performance of each student could be drawn. This map can be used as a reference system, as it includes variables as the distance from the student home to the College, that can be used as a tool to calculate the probability of success or

  5. Theoretical numerical analysis a functional analysis framework

    CERN Document Server

    Atkinson, Kendall

    2005-01-01

    This textbook prepares graduate students for research in numerical analysis/computational mathematics by giving to them a mathematical framework embedded in functional analysis and focused on numerical analysis. This helps the student to move rapidly into a research program. The text covers basic results of functional analysis, approximation theory, Fourier analysis and wavelets, iteration methods for nonlinear equations, finite difference methods, Sobolev spaces and weak formulations of boundary value problems, finite element methods, elliptic variational inequalities and their numerical solu

  6. A causal analysis relating previous achievement, attitudes, discourse, and intervention to achievement in biology and chemistry

    Science.gov (United States)

    Gooding, C. Thomas; Swift, J. Nathan; Schell, Robert E.; Swift, Patricia R.; McCroskery, James H.

    This study described the relationship of 38 variates to achievement in high school biology and chemistry classes. Forty-four teachers prepared audio tape recordings of discussions throughout a nine-month period. Equal-sized groups received treatment consisting of wait time feedback and/or supportive intervention, a form of peer coaching. Other variables were initial measures, which included the variates of class size and previous science grade, pre- and posttest scores on student attitudes and perceptions, and prediscourse and discourse analyses, which included the variates of wait times, actions, and response durations. While previous research has shown that wait time feedback and supportive intervention are effective means of changing teacher behavior, the results of the present study revealed that previous student achievement and the attitudes of students accounted for 70% of the variation in the final examination scores (New York State Regents) on the basis of only the first three weeks of data collection on the variables assessed. Generally, little emphasis on higher-level thinking, wait time, or problem solving was found at the beginning of the school year, and only minimal changes resulted from the application of the treatment variables. Pressures for content coverage and preparation for externally imposed statewide examinations that emphasize memory-level learning augured against the changes that the independent variables were designed to produce.

  7. Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity.

    Science.gov (United States)

    Seals, Douglas R; Justice, Jamie N; LaRocca, Thomas J

    2016-04-15

    Most nations of the world are undergoing rapid and dramatic population ageing, which presents great socio-economic challenges, as well as opportunities, for individuals, families, governments and societies. The prevailing biomedical strategy for reducing the healthcare impact of population ageing has been 'compression of morbidity' and, more recently, to increase healthspan, both of which seek to extend the healthy period of life and delay the development of chronic diseases and disability until a brief period at the end of life. Indeed, a recently established field within biological ageing research, 'geroscience', is focused on healthspan extension. Superimposed on this background are new attitudes and demand for 'optimal longevity' - living long, but with good health and quality of life. A key obstacle to achieving optimal longevity is the progressive decline in physiological function that occurs with ageing, which causes functional limitations (e.g. reduced mobility) and increases the risk of chronic diseases, disability and mortality. Current efforts to increase healthspan centre on slowing the fundamental biological processes of ageing such as inflammation/oxidative stress, increased senescence, mitochondrial dysfunction, impaired proteostasis and reduced stress resistance. We propose that optimization of physiological function throughout the lifespan should be a major emphasis of any contemporary biomedical policy addressing global ageing. Effective strategies should delay, reduce in magnitude or abolish reductions in function with ageing (primary prevention) and/or improve function or slow further declines in older adults with already impaired function (secondary prevention). Healthy lifestyle practices featuring regular physical activity and ideal energy intake/diet composition represent first-line function-preserving strategies, with pharmacological agents, including existing and new pharmaceuticals and novel 'nutraceutical' compounds, serving as potential

  8. Hyperspectral image classification using functional data analysis.

    Science.gov (United States)

    Li, Hong; Xiao, Guangrun; Xia, Tian; Tang, Y Y; Li, Luoqing

    2014-09-01

    The large number of spectral bands acquired by hyperspectral imaging sensors allows us to better distinguish many subtle objects and materials. Unlike other classical hyperspectral image classification methods in the multivariate analysis framework, in this paper, a novel method using functional data analysis (FDA) for accurate classification of hyperspectral images has been proposed. The central idea of FDA is to treat multivariate data as continuous functions. From this perspective, the spectral curve of each pixel in the hyperspectral images is naturally viewed as a function. This can be beneficial for making full use of the abundant spectral information. The relevance between adjacent pixel elements in the hyperspectral images can also be utilized reasonably. Functional principal component analysis is applied to solve the classification problem of these functions. Experimental results on three hyperspectral images show that the proposed method can achieve higher classification accuracies in comparison to some state-of-the-art hyperspectral image classification methods.

  9. Executive Function Skills and Academic Achievement Gains in Prekindergarten: Contributions of Learning-Related Behaviors

    Science.gov (United States)

    Nesbitt, Kimberly Turner; Farran, Dale Clark; Fuhs, Mary Wagner

    2015-01-01

    Although research suggests associations between children's executive function skills and their academic achievement, the specific mechanisms that may help explain these associations in early childhood are unclear. This study examined whether children's (N = 1,103; M age = 54.5 months) executive function skills at the beginning of prekindergarten…

  10. The Interplay of Orthodontics, Periodontics, and Restorative Dentistry to Achieve Aesthetic and Functional Success.

    Science.gov (United States)

    Trushkowsky, Richard D; Alsadah, Zainab; Brea, Luis M; Oquendo, Anabella

    2015-07-01

    Previously dentists focused on repair and maintenance of function. However, the emphasis of many patients and dentists is now on esthetics. Often there is a need for the disciplines of orthodontics, periodontics, restorative dentistry, and maxillofacial surgery to work together in order to achieve optimum results. Currently the sequencing planning process begins with esthetics and then function, structure, and ultimately biology.

  11. Executive Function Skills and Academic Achievement Gains in Prekindergarten: Contributions of Learning-Related Behaviors

    Science.gov (United States)

    Nesbitt, Kimberly Turner; Farran, Dale Clark; Fuhs, Mary Wagner

    2015-01-01

    Although research suggests associations between children's executive function skills and their academic achievement, the specific mechanisms that may help explain these associations in early childhood are unclear. This study examined whether children's (N = 1,103; M age = 54.5 months) executive function skills at the beginning of prekindergarten…

  12. Applying trait-based models to achieve functional targets for theory-driven ecological restoration.

    Science.gov (United States)

    Laughlin, Daniel C

    2014-07-01

    Manipulating community assemblages to achieve functional targets is a key component of restoring degraded ecosystems. The response-and-effect trait framework provides a conceptual foundation for translating restoration goals into functional trait targets, but a quantitative framework has been lacking for translating trait targets into assemblages of species that practitioners can actually manipulate. This study describes new trait-based models that can be used to generate ranges of species abundances to test theories about which traits, which trait values and which species assemblages are most effective for achieving functional outcomes. These models are generalisable, flexible tools that can be widely applied across many terrestrial ecosystems. Examples illustrate how the framework generates assemblages of indigenous species to (1) achieve desired community responses by applying the theories of environmental filtering, limiting similarity and competitive hierarchies, or (2) achieve desired effects on ecosystem functions by applying the theories of mass ratios and niche complementarity. Experimental applications of this framework will advance our understanding of how to set functional trait targets to achieve the desired restoration goals. A trait-based framework provides restoration ecology with a robust scaffold on which to apply fundamental ecological theory to maintain resilient and functioning ecosystems in a rapidly changing world.

  13. Educational Achievement and Black-White Inequality. Statistical Analysis Report.

    Science.gov (United States)

    Jacobson, Jonathan; Olsen, Cara; Rice, Jennifer King; Sweetland, Stephen

    This study explored relationships between black-white differences in educational achievement and black-white differences in various educational and economic outcomes. Three data sets examined the extent to which black-white differences in labor market outcomes, in educational attainment, and in mathematics and reading achievement were present for…

  14. Did Tanzania Achieve the Second Millennium Development Goal? Statistical Analysis

    Science.gov (United States)

    Magoti, Edwin

    2016-01-01

    Development Goal "Achieve universal primary education", the challenges faced, along with the way forward towards achieving the fourth Sustainable Development Goal "Ensure inclusive and equitable quality education and promote lifelong learning opportunities for all". Statistics show that Tanzania has made very promising steps…

  15. Academic Achievement, Intelligence, and Creativity: A Regression Surface Analysis.

    Science.gov (United States)

    Marjoribanks, K

    1976-01-01

    Data collected on 400 12-year-old English school children were used to examine relations between measures of intelligence, creativity and academic achievement. Complex multiple regression models, which included terms to account for the possible interaction and curvilinear relations between intelligence, creativity and academic achievement were used to construct regression surfaces. The surfaces showed that the traditional threshold hypothesis, which suggests that beyond a certain level of intelligence academic achievement is related increasingly to creativity and ceases to be related strongly to intelligence, was not supported. For some areas of academic performance the results suggest an alternate proposition, that creativity ceases to be related to achievement after a threshold level of intelligence has been reached. It was also found that at high levels of verbal ability, non-verbal ability and creativity appeared to have differential relations with academic achievement.

  16. Psychotic disorder and educational achievement : a family-based analysis

    NARCIS (Netherlands)

    Frissen, Aleida; Lieverse, Ritsaert; Marcelis, Machteld; Drukker, Marjan; Delespaul, Philippe; Cahn, W

    2015-01-01

    BACKGROUND: Early social and cognitive alterations in psychotic disorder, associated with familial liability and environmental exposures, may contribute to lower than expected educational achievement. The aims of the present study were to investigate (1) how differences in educational level between

  17. Automatic Functional Harmonic Analysis

    NARCIS (Netherlands)

    de Haas, W.B.; Magalhães, J.P.; Wiering, F.; Veltkamp, R.C.

    2013-01-01

    Music scholars have been studying tonal harmony intensively for centuries, yielding numerous theories and models. Unfortunately, a large number of these theories are formulated in a rather informal fashion and lack mathematical precision. In this article we present HarmTrace, a functional model of W

  18. Function Analysis and Decomposistion using Function Analysis Systems Technique

    Energy Technology Data Exchange (ETDEWEB)

    Wixson, James Robert

    1999-06-01

    The "Father of Value Analysis", Lawrence D. Miles, was a design engineer for General Electric in Schenectady, New York. Miles developed the concept of function analysis to address difficulties in satisfying the requirements to fill shortages of high demand manufactured parts and electrical components during World War II. His concept of function analysis was further developed in the 1960s by Charles W. Bytheway, a design engineer at Sperry Univac in Salt Lake City, Utah. Charles Bytheway extended Mile's function analysis concepts and introduced the methodology called Function Analysis Systems Technique (FAST) to the Society of American Value Engineers (SAVE) at their International Convention in 1965 (Bytheway 1965). FAST uses intuitive logic to decompose a high level, or objective function into secondary and lower level functions that are displayed in a logic diagram called a FAST model. Other techniques can then be applied to allocate functions to components, individuals, processes, or other entities that accomplish the functions. FAST is best applied in a team setting and proves to be an effective methodology for functional decomposition, allocation, and alternative development.

  19. Function Analysis and Decomposistion using Function Analysis Systems Technique

    Energy Technology Data Exchange (ETDEWEB)

    J. R. Wixson

    1999-06-01

    The "Father of Value Analysis", Lawrence D. Miles, was a design engineer for General Electric in Schenectady, New York. Miles developed the concept of function analysis to address difficulties in satisfying the requirements to fill shortages of high demand manufactured parts and electrical components during World War II. His concept of function analysis was further developed in the 1960s by Charles W. Bytheway, a design engineer at Sperry Univac in Salt Lake City, Utah. Charles Bytheway extended Mile's function analysis concepts and introduced the methodology called Function Analysis Systems Techniques (FAST) to the Society of American Value Engineers (SAVE) at their International Convention in 1965 (Bytheway 1965). FAST uses intuitive logic to decompose a high level, or objective function into secondary and lower level functions that are displayed in a logic diagram called a FAST model. Other techniques can then be applied to allocate functions to components, individuals, processes, or other entities that accomplish the functions. FAST is best applied in a team setting and proves to be an effective methodology for functional decomposition, allocation, and alternative development.

  20. Elementary functional analysis

    CERN Document Server

    Shilov, Georgi E

    1996-01-01

    Introductory text covers basic structures of mathematical analysis (linear spaces, metric spaces, normed linear spaces, etc.), differential equations, orthogonal expansions, Fourier transforms - including problems in the complex domain, especially involving the Laplace transform - and more. Each chapter includes a set of problems, with hints and answers. Bibliography. 1974 edition.

  1. Self Statements, Test Anxiety and Academic Achievement: A Correlational Analysis.

    Science.gov (United States)

    Couch, James V.; And Others

    An investigation of self-statements, test anxiety and academic achievement studied 426 college students. Research methodology is defined, demographics and student profiles for both facilitative and debilitative test anxiety are presented, with the resulting findings for each testing component. The student profile for high facilitative test anxiety…

  2. Effort Analysis: Individual Score Validation of Achievement Test Data

    Science.gov (United States)

    Wise, Steven L.

    2015-01-01

    Whenever the purpose of measurement is to inform an inference about a student's achievement level, it is important that we be able to trust that the student's test score accurately reflects what that student knows and can do. Such trust requires the assumption that a student's test event is not unduly influenced by construct-irrelevant factors…

  3. Parent Involvement and Science Achievement: A Latent Growth Curve Analysis

    Science.gov (United States)

    Johnson, Ursula Yvette

    2011-01-01

    This study examined science achievement growth across elementary and middle school and parent school involvement using the Early Childhood Longitudinal Study-Kindergarten Class of 1998-1999 (ECLS-K). The ECLS-K is a nationally representative kindergarten cohort of students from public and private schools who attended full-day or half-day…

  4. Masculinity, Educational Achievement and Social Status: A Social Network Analysis

    Science.gov (United States)

    Lusher, Dean

    2011-01-01

    This study utilises a quantitative case study social network approach to explore the connection between masculinity and scholastic achievement in two secondary, all-boys schools in Australia. In both schools two social networks representing social status are explored: the "friendship" network as a measure of status that includes…

  5. Prekindergarten Children's Executive Functioning Skills and Achievement Gains: The Utility of Direct Assessments and Teacher Ratings

    Science.gov (United States)

    Fuhs, Mary Wagner; Farran, Dale Clark; Nesbitt, Kimberly Turner

    2015-01-01

    An accumulating body of evidence suggests that young children who exhibit greater executive functioning (EF) skills in early childhood also achieve more academically. The goal of the present study was to examine the unique contributions of direct assessments and teacher ratings of children's EF skills at the beginning of prekindergarten (pre-k) to…

  6. Fine Motor Skills and Executive Function Both Contribute to Kindergarten Achievement

    Science.gov (United States)

    Cameron, Claire E.; Brock, Laura L.; Murrah, William M.; Bell, Lindsay H.; Worzalla, Samantha L.; Grissmer, David; Morrison, Frederick J.

    2012-01-01

    This study examined the contribution of executive function (EF) and multiple aspects of fine motor skills to achievement on 6 standardized assessments in a sample of middle-socioeconomic status kindergarteners. Three- and 4-year-olds' (n = 213) fine and gross motor skills were assessed in a home visit before kindergarten, EF was measured at fall…

  7. Self-Regulation, Executive Function, Working Memory, and Academic Achievement of Female High School Students

    Science.gov (United States)

    Halloran, Roberta Kathryn

    2011-01-01

    Self-regulation, executive function and working memory are areas of cognitive processing that have been studied extensively. Although many studies have examined the constructs, there is limited empirical support suggesting a formal link between the three cognitive processes and their prediction of academic achievement. Thus, the present study…

  8. Novel Vaccine Approach AchievesFunctional Cure” of AIDS Virus in Monkeys | Poster

    Science.gov (United States)

    By Frank Blanchard, Staff Writer, and Jeff Lifson, Guest Writer Scientists at the Oregon Health & Science University and the AIDS and Cancer Virus Program of the Frederick National Laboratory for Cancer Research have used a novel vaccine approach to achieve a “functional cure” and apparent eradication of infection with a monkey version of the AIDS virus.

  9. Modeling relationships between physical fitness, executive functioning, and academic achievement in primary school children

    NARCIS (Netherlands)

    van der Niet, Anneke G.; Hartman, Esther; Smith, Joanne; Visscher, Chris

    2014-01-01

    Objectives: The relationship between physical fitness and academic achievement in children has received much attention, however, whether executive functioning plays a mediating role in this relationship is unclear. The aim of this study therefore was to investigate the relationships between physical

  10. Academic and Social Achievement Goals: Their Additive, Interactive, and Specialized Effects on School Functioning

    Science.gov (United States)

    Liem, Gregory Arief D.

    2016-01-01

    Background: Students' pursuit of academic and social goals has implications for school functioning. However, studies on academic and social achievement goals have been relatively independent and mainly conducted with students in culturally Western settings. Aims: Guided by multiple-goal perspectives, this study examined the role of academic and…

  11. Modeling relationships between physical fitness, executive functioning, and academic achievement in primary school children

    NARCIS (Netherlands)

    van der Niet, Anneke G.; Hartman, Esther; Smith, Joanne; Visscher, Chris

    Objectives: The relationship between physical fitness and academic achievement in children has received much attention, however, whether executive functioning plays a mediating role in this relationship is unclear. The aim of this study therefore was to investigate the relationships between physical

  12. Decreased latent inhibition is associated with increased creative achievement in high-functioning individuals.

    Science.gov (United States)

    Carson, Shelley H; Peterson, Jordan B; Higgins, Daniel M

    2003-09-01

    Reductions in latent inhibition (LI), the capacity to screen from conscious awareness stimuli previously experienced as irrelevant, have been generally associated with the tendency towards psychosis. However, "failure" to screen out previously irrelevant stimuli might also hypothetically contribute to original thinking, particularly in combination with high IQ. Meta-analysis of two studies, conducted on youthful high-IQ samples. demonstrated that high lifetime creative achievers had significantly lower LI scores than low creative achievers (r(effect size) = .31, p = .0003, one-tailed). Eminent creative achievers (participants under 21 years who reported unusually high scores in a single domain of creative achievement) were 7 times more likely to have low rather than high LI scores, chi2 (1, N = 25) = 10.69, phi = .47. p = .003.

  13. Physical Activity, Fitness, Cognitive Function, and Academic Achievement in Children: A Systematic Review.

    Science.gov (United States)

    Donnelly, Joseph E; Hillman, Charles H; Castelli, Darla; Etnier, Jennifer L; Lee, Sarah; Tomporowski, Phillip; Lambourne, Kate; Szabo-Reed, Amanda N

    2016-06-01

    The relationship among physical activity (PA), fitness, cognitive function, and academic achievement in children is receiving considerable attention. The utility of PA to improve cognition and academic achievement is promising but uncertain; thus, this position stand will provide clarity from the available science. The purpose of this study was to answer the following questions: 1) among children age 5-13 yr, do PA and physical fitness influence cognition, learning, brain structure, and brain function? 2) Among children age 5-13 yr, do PA, physical education (PE), and sports programs influence standardized achievement test performance and concentration/attention? This study used primary source articles published in English in peer-reviewed journals. Articles that presented data on, PA, fitness, or PE/sport participation and cognition, learning, brain function/structure, academic achievement, or concentration/attention were included. Two separate searches were performed to identify studies that focused on 1) cognition, learning, brain structure, and brain function and 2) standardized achievement test performance and concentration/attention. PubMed, ERIC, PsychInfo, SportDiscus, Scopus, Web of Science, Academic Search Premier, and Embase were searched (January 1990-September 2014) for studies that met inclusion criteria. Sixty-four studies met inclusion criteria for the first search (cognition/learning/brain), and 73 studies met inclusion criteria for the second search (academic achievement/concentration). Articles were grouped by study design as cross-sectional, longitudinal, acute, or intervention trials. Considerable heterogeneity existed for several important study parameters; therefore, results were synthesized and presented by study design. A majority of the research supports the view that physical fitness, single bouts of PA, and PA interventions benefit children's cognitive functioning. Limited evidence was available concerning the effects of PA on learning

  14. Transform analysis of generalized functions

    CERN Document Server

    Misra, O P

    1986-01-01

    Transform Analysis of Generalized Functions concentrates on finite parts of integrals, generalized functions and distributions. It gives a unified treatment of the distributional setting with transform analysis, i.e. Fourier, Laplace, Stieltjes, Mellin, Hankel and Bessel Series.Included are accounts of applications of the theory of integral transforms in a distributional setting to the solution of problems arising in mathematical physics. Information on distributional solutions of differential, partial differential equations and integral equations is conveniently collected here.The volume will

  15. Functional Equations and Fourier Analysis

    OpenAIRE

    2010-01-01

    By exploring the relations among functional equations, harmonic analysis and representation theory, we give a unified and very accessible approach to solve three important functional equations -- the d'Alembert equation, the Wilson equation, and the d'Alembert long equation, on compact groups.

  16. Functional Analysis for Chemical Engineers.

    Science.gov (United States)

    Ramkrishna, D.

    1979-01-01

    Described is a graduate level engineering course on functional analysis offered at Purdue University. The course restricts itself to linear problems, specifically analysis of linear operators on vector spaces. Key applications in the course demonstrating the utility of abstract formulations are presented. (BT)

  17. Executive functions in 5- to 8-year olds: Developmental changes and relationship to academic achievement

    OpenAIRE

    Röthlisberger, Marianne; Neuenschwander, Regula; Cimeli, Patrizia; Roebers, Claudia M.

    2013-01-01

    Pronounced improvements in executive functions (EF) during preschool years have been documented in cross-sectional studies. However, longitudinal evidence on EF development during the transition to school and predictive associations between early EF and later school achievement are still scarce. This study examined developmental changes in EF across three time-points, the predictive value of EF for mathematical, reading and spelling skills and explored children's specific academic attainment ...

  18. Multilevel sparse functional principal component analysis.

    Science.gov (United States)

    Di, Chongzhi; Crainiceanu, Ciprian M; Jank, Wolfgang S

    2014-01-29

    We consider analysis of sparsely sampled multilevel functional data, where the basic observational unit is a function and data have a natural hierarchy of basic units. An example is when functions are recorded at multiple visits for each subject. Multilevel functional principal component analysis (MFPCA; Di et al. 2009) was proposed for such data when functions are densely recorded. Here we consider the case when functions are sparsely sampled and may contain only a few observations per function. We exploit the multilevel structure of covariance operators and achieve data reduction by principal component decompositions at both between and within subject levels. We address inherent methodological differences in the sparse sampling context to: 1) estimate the covariance operators; 2) estimate the functional principal component scores; 3) predict the underlying curves. Through simulations the proposed method is able to discover dominating modes of variations and reconstruct underlying curves well even in sparse settings. Our approach is illustrated by two applications, the Sleep Heart Health Study and eBay auctions.

  19. Motor coordination correlates with academic achievement and cognitive function in children

    Directory of Open Access Journals (Sweden)

    Valter Rocha Fernandes

    2016-03-01

    Full Text Available The relationship between exercise and cognition is an important topic of research that only recently began to unravel. Here we set out to investigate the relation between motor skills, cognitive function and school performance in 45 students from 8 to 14 years of age. We used a cross-sectional design to evaluate motor coordination (Touch Test Disc, agility (Shuttle Run Speed - running back and forth, school performance (Academic Achievement Test, the Stroop test and 6 sub-tests of the Wechsler Intelligence Scale for Children-IV (WISC-IV. We found that the Touch Test Disc was the best predictor of school performance (R²=0.20. Significant correlations were also observed between motor coordination and several indices of cognitive function, such as the total score of the Academic Achievement Test (Spearman’s rho=0.536; p<=0.001, as well as two WISC-IV sub-tests: block design (R= -0.438;p=0.003 and cancellation (rho= -0.471; p=0.001. All the other cognitive variables pointed in the same direction, and even correlated with agility, but did not reach statistical significance. Altogether, the data indicate that visual motor coordination and visual selective attention, but not agility, may influence academic achievement and cognitive function. The results highlight the importance of investigating the correlation between physical skills and different aspects of cognition.

  20. Growth, functional capacities and motivation for achievement and competitiveness in youth basketball: an interdisciplinary approach.

    Science.gov (United States)

    Carvalho, Humberto Moreira; Gonçalves, Carlos E; Collins, Dave; Paes, Roberto R

    2017-06-12

    The interaction of multiple influences on the path to sport success is not yet fully understood by sport scientists. In this study, we examined variation in body size, functional capacities and motivation for achievement, competitiveness and deliberate practice of youth basketball players associated with differences in biological maturity status, chronological age and years of training experience. Reflecting the importance of interactive effects, we examined the relationships between the psychological variables and functional capacities. Fifty-eight male basketball players aged 9.5 to 15.5 years were considered. Variables included chronological age, estimated age at peak height velocity, stature, body mass and sitting height by anthropometry; the Work and Family Orientation and Deliberate Practice Motivation Questionnaires were also used. Finally, the Line Drill test and Yo-Yo Intermittent Recovery level 1 (Yo-Yo IR1) tests were used as functional capacities indicators for basketball. Variance components models derived from series of multilevel linear regression models revealed a substantial variation by maturity status for body size, functional capacities indicators, mastery and will to excel. The influence of estimated maturity status on mastery and will to excel was independent of age and years of experience. In contrast, no relationships were observed between psychological variables and functional capacities indicators. We conclude that growth-related changes are relevant to understanding players´ motivations for achievement, competitiveness and deliberate practice. This should be of interest to those involved in the selection and development of youth basketball players.

  1. Uniting academic achievements on performance analysis with industrial needs

    NARCIS (Netherlands)

    Theelen, Bart; Hooman, Jozef

    2015-01-01

    In our mission to advance innovation by industrial adoption of academic results, we perform many projects with high-tech industries. Favoring formal methods, we observe a gap between industrial needs in performance modeling and the analysis capabilities of formal methods for this goal. After clarify

  2. Functional and shape data analysis

    CERN Document Server

    Srivastava, Anuj

    2016-01-01

    This textbook for courses on function data analysis and shape data analysis describes how to define, compare, and mathematically represent shapes, with a focus on statistical modeling and inference. It is aimed at graduate students in analysis in statistics, engineering, applied mathematics, neuroscience, biology, bioinformatics, and other related areas. The interdisciplinary nature of the broad range of ideas covered—from introductory theory to algorithmic implementations and some statistical case studies—is meant to familiarize graduate students with an array of tools that are relevant in developing computational solutions for shape and related analyses. These tools, gleaned from geometry, algebra, statistics, and computational science, are traditionally scattered across different courses, departments, and disciplines; Functional and Shape Data Analysis offers a unified, comprehensive solution by integrating the registration problem into shape analysis, better preparing graduate students for handling fu...

  3. Correlation Between Executive Function Behaviors and Educational Achievement of Children With Developmental Coordination Disorder

    Directory of Open Access Journals (Sweden)

    Maleki

    2016-06-01

    Full Text Available Background Developmental cordination disorder (DCD is a serious deficit in development of motor coordination, which affects educational achievements and daily life activities to a considerable extent. Objectives The present study aimed to investigate correlations between components of executive function and spelling and math performance of 7 - 11-year-old children with DCD. Materials and Methods A descriptive-analytic study was conducted on 53 primary school children with DCD. Persian version of motor observation questionnaire for teachers (PMOQ-T was used to detect DCD. Executive functions and educational achievements of these children were evaluated using behavior rating inventory of executive function (BRIEF and a researcher-made test, respectively. Results were analyzed through SPSS software (v. 21 and Pearson correlation coefficient. Results The findings showed that components of inhibition (r = -0.27, P < 0.05, working memory (r = -0.44, P < 0.01 and organization of material (r = -0.28, P < 0.05 were significantly correlated with the spelling test. And components of inhibition (r = -0.27, P < 0.05, shift (r = -0.38, P < 0. 01, working memory (r = -0.28, P < 0.05, and planning (r = -.29, P<0.05 were correlated with math test. Conclusions The results may help clinicians for early intervention and focus on related components of executive function to improve the educational performance of DCD children. Knowing that executive function skills are associated with these two achievement domains suggests potentiality of targeted math and spelling interventions for DCD children.

  4. Executive functioning and reading achievement in school: a study of Brazilian children assessed by their teachers as "poor readers".

    Science.gov (United States)

    Engel de Abreu, Pascale M J; Abreu, Neander; Nikaedo, Carolina C; Puglisi, Marina L; Tourinho, Carlos J; Miranda, Mônica C; Befi-Lopes, Debora M; Bueno, Orlando F A; Martin, Romain

    2014-01-01

    This study examined executive functioning and reading achievement in 106 6- to 8-year-old Brazilian children from a range of social backgrounds of whom approximately half lived below the poverty line. A particular focus was to explore the executive function profile of children whose classroom reading performance was judged below standard by their teachers and who were matched to controls on chronological age, sex, school type (private or public), domicile (Salvador/BA or São Paulo/SP) and socioeconomic status. Children completed a battery of 12 executive function tasks that were conceptual tapping cognitive flexibility, working memory, inhibition and selective attention. Each executive function domain was assessed by several tasks. Principal component analysis extracted four factors that were labeled "Working Memory/Cognitive Flexibility," "Interference Suppression," "Selective Attention," and "Response Inhibition." Individual differences in executive functioning components made differential contributions to early reading achievement. The Working Memory/Cognitive Flexibility factor emerged as the best predictor of reading. Group comparisons on computed factor scores showed that struggling readers displayed limitations in Working Memory/Cognitive Flexibility, but not in other executive function components, compared to more skilled readers. These results validate the account that working memory capacity provides a crucial building block for the development of early literacy skills and extends it to a population of early readers of Portuguese from Brazil. The study suggests that deficits in working memory/cognitive flexibility might represent one contributing factor to reading difficulties in early readers. This might have important implications for how educators might intervene with children at risk of academic under achievement.

  5. Structured Functional Principal Component Analysis

    Science.gov (United States)

    Shou, Haochang; Zipunnikov, Vadim; Crainiceanu, Ciprian M.; Greven, Sonja

    2015-01-01

    Summary Motivated by modern observational studies, we introduce a class of functional models that expand nested and crossed designs. These models account for the natural inheritance of the correlation structures from sampling designs in studies where the fundamental unit is a function or image. Inference is based on functional quadratics and their relationship with the underlying covariance structure of the latent processes. A computationally fast and scalable estimation procedure is developed for high-dimensional data. Methods are used in applications including high-frequency accelerometer data for daily activity, pitch linguistic data for phonetic analysis, and EEG data for studying electrical brain activity during sleep. PMID:25327216

  6. Cognitive, Parent and Teacher Rating Measures of Executive Functioning: Shared and Unique Influences on School Achievement.

    Science.gov (United States)

    Dekker, Marielle C; Ziermans, Tim B; Spruijt, Andrea M; Swaab, Hanna

    2017-01-01

    Very little is known about the relative influence of cognitive performance-based executive functioning (EF) measures and behavioral EF ratings in explaining differences in children's school achievement. This study examined the shared and unique influence of these different EF measures on math and spelling outcome for a sample of 84 first and second graders. Parents and teachers completed the Behavior Rating Inventory of Executive Function (BRIEF), and children were tested with computer-based performance tests from the Amsterdam Neuropsychological Tasks (ANT). Mixed-model hierarchical regression analyses, including intelligence level and age, showed that cognitive performance and teacher's ratings of working memory and shifting concurrently explained differences in spelling. However, teacher's behavioral EF ratings did not explain any additional variance in math outcome above cognitive EF performance. Parent's behavioral EF ratings did not add any unique information for either outcome measure. This study provides support for the ecological validity of performance- and teacher rating-based EF measures, and shows that both measures could have a complementary role in identifying EF processes underlying spelling achievement problems. The early identification of strengths and weaknesses of a child's working memory and shifting capabilities, might help teachers to broaden their range of remedial intervention options to optimize school achievement.

  7. Cognitive, Parent and Teacher Rating Measures of Executive Functioning: Shared and Unique Influences on School Achievement

    Science.gov (United States)

    Dekker, Marielle C.; Ziermans, Tim B.; Spruijt, Andrea M.; Swaab, Hanna

    2017-01-01

    Very little is known about the relative influence of cognitive performance-based executive functioning (EF) measures and behavioral EF ratings in explaining differences in children's school achievement. This study examined the shared and unique influence of these different EF measures on math and spelling outcome for a sample of 84 first and second graders. Parents and teachers completed the Behavior Rating Inventory of Executive Function (BRIEF), and children were tested with computer-based performance tests from the Amsterdam Neuropsychological Tasks (ANT). Mixed-model hierarchical regression analyses, including intelligence level and age, showed that cognitive performance and teacher's ratings of working memory and shifting concurrently explained differences in spelling. However, teacher's behavioral EF ratings did not explain any additional variance in math outcome above cognitive EF performance. Parent's behavioral EF ratings did not add any unique information for either outcome measure. This study provides support for the ecological validity of performance- and teacher rating-based EF measures, and shows that both measures could have a complementary role in identifying EF processes underlying spelling achievement problems. The early identification of strengths and weaknesses of a child's working memory and shifting capabilities, might help teachers to broaden their range of remedial intervention options to optimize school achievement. PMID:28194121

  8. AUDIT FUNCTION ROLE IN ACHIEVING AN EFFICIENT CORPORATE GOVERNANCE – CONCEPTUAL MODEL PROPOSAL

    Directory of Open Access Journals (Sweden)

    Melinda Timea Fülöp

    2013-12-01

    Full Text Available Nowadays corporate governance plays an important role in decisions making processes, which represents a relatively new approach for both Romanian scientific studies and practice. As a consequence we consider the increased attention given to corporate governance to be crucial, especially addressing the role of the audit function and the importance of the corporate governance code. Audit function is of particular practical importance in corporate governance, therefore we decided meticulously to consider it, and especially to develop a conceptual framework for its role in support of an effective corporate governance. We consider that there are two levels and seven key elements utilized in order to achieve an effective corporate governance. In conclusion, audit function as a whole, with an active role in improving corporate governance, should perform correlated in terms of its components: internal audit, external audit and audit committees.

  9. Special functions in Fuzzy Analysis

    Directory of Open Access Journals (Sweden)

    Angel Garrido

    2006-01-01

    Full Text Available In the treatment of Fuzzy Logic an useful tool appears: the membership function, with the information about the degree of completion of a condition which defines the respective Fuzzy Set or Fuzzy Relation. With their introduction, it is possible to prove some results on the foundations of Fuzzy Logic and open new ways in Fuzzy Analysis.

  10. Fifteen papers on functional analysis

    CERN Document Server

    Allakhverdiev, B P; Fainshtein, A S; Khelemskii, AYa; Klenina, LI

    1984-01-01

    The papers in this volume cover topics on functional analysis. They have been selected, translated, and edited from publications not otherwise translated into English under the auspices of the AMS-ASL-IMS Committee on Translations from Russian and Other Foreign Languages.

  11. Function analysis of unknown genes

    DEFF Research Database (Denmark)

    Rogowska-Wrzesinska, A.

    2002-01-01

      This thesis entitled "Function analysis of unknown genes" presents the use of proteome analysis for the characterisation of yeast (Saccharomyces cerevisiae) genes and their products (proteins especially those of unknown function). This study illustrates that proteome analysis can be used...... to describe different aspects of molecular biology of the cell, to study changes that occur in the cell due to overexpression or deletion of a gene and to identify various protein modifications. The biological questions and the results of the described studies show the diversity of the information that can...... genes and proteins. It reports the first global proteome database collecting 36 yeast single gene deletion mutants and selecting over 650 differences between analysed mutants and the wild type strain. The obtained results show that two-dimensional gel electrophoresis and mass spectrometry based proteome...

  12. How preschool executive functioning predicts several aspects of math achievement in Grades 1 and 3: A longitudinal study.

    Science.gov (United States)

    Viterbori, Paola; Usai, M Carmen; Traverso, Laura; De Franchis, Valentina

    2015-12-01

    This longitudinal study analyzes whether selected components of executive function (EF) measured during the preschool period predict several indices of math achievement in primary school. Six EF measures were assessed in a sample of 5-year-old children (N = 175). The math achievement of the same children was then tested in Grades 1 and 3 using both a composite math score and three single indices of written calculation, arithmetical facts, and problem solving. Using previous results obtained from the same sample of children, a confirmatory factor analysis examining the latent EF structure in kindergarten indicated that a two-factor model provided the best fit for the data. In this model, inhibition and working memory (WM)-flexibility were separate dimensions. A full structural equation model was then used to test the hypothesis that math achievement (the composite math score and single math scores) in Grades 1 and 3 could be explained by the two EF components comprising the kindergarten model. The results indicate that the WM-flexibility component measured during the preschool period substantially predicts mathematical achievement, especially in Grade 3. The math composite scores were predicted by the WM-flexibility factor at both grade levels. In Grade 3, both problem solving and arithmetical facts were predicted by the WM-flexibility component. The results empirically support interventions that target EF as an important component of early childhood mathematics education.

  13. What Happens to the Fish's Achievement in a Little Pond? A Simultaneous Analysis of Class-Average Achievement Effects on Achievement and Academic Self-Concept

    Science.gov (United States)

    Stäbler, Franziska; Dumont, Hanna; Becker, Michael; Baumert, Jürgen

    2017-01-01

    Empirical studies have demonstrated that students who are taught in a group of students with higher average achievement benefit in terms of their achievement. However, there is also evidence showing that being surrounded by high-achieving students has a negative effect on students' academic self-concept, also known as the big-fish--little-pond…

  14. De-randomizing Shannon: The Design and Analysis of a Capacity-Achieving Rateless Code

    CERN Document Server

    Balakrishnan, Hari; Perry, Jonathan; Shah, Devavrat

    2012-01-01

    This paper presents an analysis of spinal codes, a class of rateless codes proposed recently. We prove that spinal codes achieve Shannon capacity for the binary symmetric channel (BSC) and the additive white Gaussian noise (AWGN) channel with an efficient polynomial-time encoder and decoder. They are the first rateless codes with proofs of these properties for BSC and AWGN. The key idea in the spinal code is the sequential application of a hash function over the message bits. The sequential structure of the code turns out to be crucial for efficient decoding. Moreover, counter to the wisdom of having an expander structure in good codes, we show that the spinal code, despite its sequential structure, achieves capacity. The pseudo-randomness provided by a hash function suffices for this purpose. Our proof introduces a variant of Gallager's result characterizing the error exponent of random codes for any memoryless channel. We present a novel application of these error-exponent results within the framework of an...

  15. Parametric functional principal component analysis.

    Science.gov (United States)

    Sang, Peijun; Wang, Liangliang; Cao, Jiguo

    2017-03-10

    Functional principal component analysis (FPCA) is a popular approach in functional data analysis to explore major sources of variation in a sample of random curves. These major sources of variation are represented by functional principal components (FPCs). Most existing FPCA approaches use a set of flexible basis functions such as B-spline basis to represent the FPCs, and control the smoothness of the FPCs by adding roughness penalties. However, the flexible representations pose difficulties for users to understand and interpret the FPCs. In this article, we consider a variety of applications of FPCA and find that, in many situations, the shapes of top FPCs are simple enough to be approximated using simple parametric functions. We propose a parametric approach to estimate the top FPCs to enhance their interpretability for users. Our parametric approach can also circumvent the smoothing parameter selecting process in conventional nonparametric FPCA methods. In addition, our simulation study shows that the proposed parametric FPCA is more robust when outlier curves exist. The parametric FPCA method is demonstrated by analyzing several datasets from a variety of applications. © 2017, The International Biometric Society.

  16. EVENT PLANNING USING FUNCTION ANALYSIS

    Energy Technology Data Exchange (ETDEWEB)

    Lori Braase; Jodi Grgich

    2011-06-01

    Event planning is expensive and resource intensive. Function analysis provides a solid foundation for comprehensive event planning (e.g., workshops, conferences, symposiums, or meetings). It has been used at Idaho National Laboratory (INL) to successfully plan events and capture lessons learned, and played a significant role in the development and implementation of the “INL Guide for Hosting an Event.” Using a guide and a functional approach to planning utilizes resources more efficiently and reduces errors that could be distracting or detrimental to an event. This integrated approach to logistics and program planning – with the primary focus on the participant – gives us the edge.

  17. Cephalometric analysis for functional occlusion

    Directory of Open Access Journals (Sweden)

    Ashok Karad

    2016-01-01

    Full Text Available Background: Various elements contributing to good functional occlusion have not been clearly assessed with cephalometrics for the diagnosis of functional problems and their application in clinical practice. The aim of this study, therefore, was to analyze different components of functional occlusion to formulate concise functional cephalometric analysis. Materials and Methods: Eighty-two cases (38 males and 44 females, with class I occlusion and balanced facial profile, were examined based on the selection criteria, and cephalograms were taken in natural head position. All the radiographs were then analyzed using various functional parameters. Results: The mean values of condylar path angle and incisal path angle were 55.83° and 65.67°, respectively, with large deviations. However, both showed positive correlation. The value of the angle of long axis of mandibular incisor with respect to the line joining center of condyle and lower incisor tip was 88.04°. Moreover, the angle between the occlusal plane and horizontal plane was 12.88°. In vertical plane, lower face height (LFH was found to be slightly less than the upper face height. Maxilla contributed around 45% of the LFH while mandible formed about 60%. Furthermore, upper alveolar component (maxillary alveolar height formed more than half of the maxilla (53.79% whereas lower alveolar component (mandibular alveolar height was 74.8% of the mandible. Conclusion: This study has analyzed various components of functional occlusion and formulated a concise functional cephalometric analysis for diagnosis, treatment planning, and assessment of treatment results.

  18. Effects of the Peer Group on the Development of Social Functioning and Academic Achievement: A Longitudinal Study in Chinese Children

    Science.gov (United States)

    Chen, Xinyin; Chang, Lei; Liu, Hongyun; He, Yunfeng

    2008-01-01

    This longitudinal study examined, in a sample of Chinese children (initial mean ages = 9.5 and 12.7 years, N = 505), how the peer group contributed to social functioning and academic achievement and their associations. Data on informal peer groups, social functioning, and academic achievement were collected from multiple sources. Multilevel…

  19. Executive Functioning and Reading Achievement in School: A study of Brazilian Children Assessed by Their Teachers as Poor Readers

    Directory of Open Access Journals (Sweden)

    Pascale M. J. Engel de Abreu

    2014-06-01

    Full Text Available This study examined executive functioning and reading achievement in 106 6- to 8-year-old Brazilian children from a range of social backgrounds of whom approximately half lived below the poverty line. A particular focus was to explore the executive function profile of children whose classroom reading performance was judged below standard by their teachers and who were carefully matched to controls on chronological age, sex, school type (Private or Public, domicile (Salvador/BA or São Paulo/SP, and socioeconomic status. Children completed a battery of 12 executive function tasks that were conceptually tapping cognitive flexibility, working memory, inhibition, and selective attention. Each executive function domain was assessed by several tasks. Principal component analysis extracted four factors that were labeled Working Memory/Cognitive Flexibility, Interference Suppression, Selective Attention, and Response Inhibition. Individual differences in executive functioning components made differential contributions to early reading achievement. The Working Memory/Cognitive Flexibility factor emerged as the best predictor of reading. Group comparisons on computed factor scores showed that the struggling readers presented limitations in Working Memory/Cognitive Flexibility, but not in other executive function components, compared to more skilled readers. These results validate the account that working memory capacity provides a crucial building block for the development of early literacy skills and extends it to a population of early readers of Portuguese from Brazil. The study suggests that deficits in working memory/cognitive flexibility might represent one contributing factor to reading difficulties in early readers which might have important implications for interventions for children at risk of school failure.

  20. Functional analysis theory and applications

    CERN Document Server

    Edwards, RE

    2011-01-01

    ""The book contains an enormous amount of information - mathematical, bibliographical and historical - interwoven with some outstanding heuristic discussions."" - Mathematical Reviews.In this massive graduate-level study, Emeritus Professor Edwards (Australian National University, Canberra) presents a balanced account of both the abstract theory and the applications of linear functional analysis. Written for readers with a basic knowledge of set theory, general topology, and vector spaces, the book includes an abundance of carefully chosen illustrative examples and excellent exercises at the

  1. The Measurement of Executive Function at Age 5: Psychometric Properties and Relationship to Academic Achievement

    Science.gov (United States)

    Willoughby, Michael T.; Blair, Clancy B.; Wirth, R.J.; Greenberg, Mark

    2012-01-01

    This study examined the psychometric properties and criterion validity of a newly developed battery of executive function tasks for use in early childhood. The battery was included in the Family Life Project (FLP), a prospective longitudinal study of families who were over-sampled from low income and African American families at the birth of a new child (N = 1292). Ninety-nine percent (N = 1036) of children who participated in the age 5 home visit completed one or more (M = 5.8, Median = 6) of the six executive function tasks. Results indicated that tasks worked equally well for children residing in low and not low income homes, that task scores were most informative about the ability level of children in the low-average range, that performance on executive function tasks was best characterized by a single factor, and that individual differences on the EF battery were strongly related to a latent variable measuring overall academic achievement, as well as with individual standardized tests that measured phonological awareness, letter-word identification, and early math skills. PMID:21966934

  2. A Meta-Analysis on the Factors That Best Reduce the Achievement Gap

    Science.gov (United States)

    Jeynes, William H.

    2015-01-01

    A meta-analyses was undertaken to determine the factors that are most related with reducing the achievement gap. The meta-analysis included 30 studies that examined attempts to bridge the achievement gap between White students on one hand and Black and Latino students on the other. The results indicate that several factors are associated with a…

  3. Topics in nonlinear functional analysis

    CERN Document Server

    Nirenberg, Louis

    2001-01-01

    Since its first appearance as a set of lecture notes published by the Courant Institute in 1974, this book served as an introduction to various subjects in nonlinear functional analysis. The current edition is a reprint of these notes, with added bibliographic references. Topological and analytic methods are developed for treating nonlinear ordinary and partial differential equations. The first two chapters of the book introduce the notion of topological degree and develop its basic properties. These properties are used in later chapters in the discussion of bifurcation theory (the possible br

  4. Warped functional analysis of variance.

    Science.gov (United States)

    Gervini, Daniel; Carter, Patrick A

    2014-09-01

    This article presents an Analysis of Variance model for functional data that explicitly incorporates phase variability through a time-warping component, allowing for a unified approach to estimation and inference in presence of amplitude and time variability. The focus is on single-random-factor models but the approach can be easily generalized to more complex ANOVA models. The behavior of the estimators is studied by simulation, and an application to the analysis of growth curves of flour beetles is presented. Although the model assumes a smooth latent process behind the observed trajectories, smootheness of the observed data is not required; the method can be applied to irregular time grids, which are common in longitudinal studies.

  5. Self-concept and academic achievement: a meta-analysis of longitudinal relations.

    Science.gov (United States)

    Huang, Chiungjung

    2011-10-01

    The relation between self-concept and academic achievement was examined in 39 independent and longitudinal samples through the integration of meta-analysis and path analysis procedures. For relations with more than 3 independent samples, the mean observed correlations ranged from .20 to .27 between prior self-concept and subsequent academic achievement and from .19 to .25 between prior academic achievement and subsequent self-concept. Globality/specificity of self-concept was the only significant moderating factor in the relation between (a) prior self-concept and subsequent academic achievement and (b) prior academic achievement and subsequent self-concept. As high self-concept is related to high academic performance and vice-versa, intervention programs that combine self-enhancement and skill development should be integrated.

  6. Occupational Functionality: A Concept Analysis.

    Science.gov (United States)

    Combs, Bryan; Heaton, Karen

    2016-08-01

    Occupational health nursing has evolved since the late 19th century and, with the inclusion of advanced practice nursing, has become essential to the health and safety of workers. A key component of the knowledge required of advanced practice occupational health nurses is an understanding of what it means for workers to be fit for duty The definition or concept of being fit for duty varies depending on the point-of-view of the health care provider. Health care providers across all professions must have a consistent understanding of what it means to be fit for duty Literature shows that professions and specialties that often collaborate have varying ideas about what it means to be fit for duty These differences highlight the need for a consistent concept that can be used across professions, is holistic, and incorporates other concepts critical to all points of view. To better understand fit for duty, a concept analysis, using the Walker and Avant framework, focused on the concept of occupational functionality (OF). Occupational functionality is best defined as the qualities of being suited to serve an occupational purpose efficiently and effectively within the physical, occupational, environmental, and psychological demands of a unique work setting. This concept analysis offers an initial step in understanding fit for duty and gives health care providers a concept that can be used across disciplines.

  7. Functional Analysis: Entering Hilbert Space

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    In the second edition, I have expanded the material on normed vector spaces and their operators presented in Chapter 1 to include proofs of the Open Map-ping Theorem, the Closed Graph Theorem and the Hahn-Banach The orem. The material on operators between normed vector spaces is further expanded...... of the new material on normed vector spaces and their operators, the book can hopefully serve as a general introduction to functional analysis viewed as a theory of infinite dimensional linear spaces and linear operators acting on them....... in a new chapter on Fredholm theory (Chapter 6). Fredholm theory originates in pioneering work of the Swedish mathematician Erik Ivar Fred-holm on integral equations, which inspired the study of a new class of bounded linear operators, known as Fredholm operators. Chapter 6 presents the basic elements...

  8. Gifted Ethnic Minority Students and Academic Achievement: A Meta-Analysis

    Science.gov (United States)

    Henfield, Malik S.; Woo, Hongryun; Bang, Na Mi

    2017-01-01

    We conducted a meta-analysis exploring ethnic minority students enrolled in gifted/advanced programs with an emphasis on their academic achievement outcomes. A comprehensive search based on the Transparent Reporting of Systematic Reviews and Meta-Analysis checklist, was performed to retrieve articles within a 30-year time period (1983-2014), which…

  9. Gifted Ethnic Minority Students and Academic Achievement: A Meta-Analysis

    Science.gov (United States)

    Henfield, Malik S.; Woo, Hongryun; Bang, Na Mi

    2017-01-01

    We conducted a meta-analysis exploring ethnic minority students enrolled in gifted/advanced programs with an emphasis on their academic achievement outcomes. A comprehensive search based on the Transparent Reporting of Systematic Reviews and Meta-Analysis checklist, was performed to retrieve articles within a 30-year time period (1983-2014), which…

  10. Functional Analysis in Applied Mathematics and Engineering

    DEFF Research Database (Denmark)

    Pedersen, Michael

    1997-01-01

    Lecture notes for the course 01245 Functional Analysis. Consists of the first part of amonograph with the same title.......Lecture notes for the course 01245 Functional Analysis. Consists of the first part of amonograph with the same title....

  11. Contributions of executive function and spatial skills to preschool mathematics achievement.

    Science.gov (United States)

    Verdine, Brian N; Irwin, Casey M; Golinkoff, Roberta Michnick; Hirsh-Pasek, Kathryn

    2014-10-01

    Early mathematics achievement is highly predictive of later mathematics performance. Here we investigated the influence of executive function (EF) and spatial skills, two generalizable skills often overlooked in mathematics curricula, on mathematics performance in preschoolers. Children (N=44) of varying socioeconomic status (SES) levels were assessed at 3 years of age on a new assessment of spatial skill (Test of Spatial Assembly, TOSA) and a vocabulary measure (Peabody Picture Vocabulary Test, PPVT). The same children were tested at 4 years of age on the Beery Test of Visual-Motor Integration (VMI) as well as on measures of EF and mathematics. The TOSA was created specifically as an assessment for 3-year-olds, allowing the investigation of links among spatial, EF, and mathematical skills earlier than previously possible. Results of a hierarchical regression indicate that EF and spatial skills predict 70% of the variance in mathematics performance without an explicit math test, EF is an important predictor of math performance as prior research suggested, and spatial skills uniquely predict 27% of the variance in mathematics skills. Additional research is needed to understand whether EF is truly malleable and whether EF and spatial skills may be leveraged to support early mathematics skills, especially for lower SES children who are already falling behind in these skill areas by 3 and 4 years of age. These findings indicate that both skills are part of an important foundation for mathematics performance and may represent pathways for improving school readiness for mathematics. Copyright © 2014 Elsevier Inc. All rights reserved.

  12. Tolerancing analysis and functional requirement

    CERN Document Server

    Petit, Jean-Philippe

    2010-01-01

    The aim of this paper is to show through a simple assembly a method of tolerancing analysis (coherent with GPS) developed at LM\\'ecA and based on the model of clearance and deviation domains. Tolerancing is an important step in the product design because on it will depend the functionality of the mechanism its assemblibility but also its cost: manufacturing cost increases with the precision of tolerances values. In our model, each feature specification is translated into tolerance zone. This zone limits displacements of the toleranced feature. Limitations of this small displacements are expressed in a mathematical form by a 6-polytope in a 6 dimensions space (3 rotations and 3 translations). In the same way, contact conditions in joints allow to write linear inequalities which can be translated by 6-polytopes. Each domain is defined by a set of vertices and a system of inequalities. Considering a chosen tolerancing, the method allows to verify the mechanism assemblibility but also several functional requireme...

  13. Interpretable functional principal component analysis.

    Science.gov (United States)

    Lin, Zhenhua; Wang, Liangliang; Cao, Jiguo

    2016-09-01

    Functional principal component analysis (FPCA) is a popular approach to explore major sources of variation in a sample of random curves. These major sources of variation are represented by functional principal components (FPCs). The intervals where the values of FPCs are significant are interpreted as where sample curves have major variations. However, these intervals are often hard for naïve users to identify, because of the vague definition of "significant values". In this article, we develop a novel penalty-based method to derive FPCs that are only nonzero precisely in the intervals where the values of FPCs are significant, whence the derived FPCs possess better interpretability than the FPCs derived from existing methods. To compute the proposed FPCs, we devise an efficient algorithm based on projection deflation techniques. We show that the proposed interpretable FPCs are strongly consistent and asymptotically normal under mild conditions. Simulation studies confirm that with a competitive performance in explaining variations of sample curves, the proposed FPCs are more interpretable than the traditional counterparts. This advantage is demonstrated by analyzing two real datasets, namely, electroencephalography data and Canadian weather data.

  14. Functional Analysis and Treatment of Nail Biting

    Science.gov (United States)

    Dufrene, Brad A.; Watson, T. Steuart; Kazmerski, Jennifer S.

    2008-01-01

    This study applied functional analysis methodology to nail biting exhibited by a 24-year-old female graduate student. Results from the brief functional analysis indicated variability in nail biting across assessment conditions. Functional analysis data were then used to guide treatment development and implementation. Treatment included a…

  15. Functional 2D Procrustes Shape Analysis

    DEFF Research Database (Denmark)

    Larsen, Rasmus

    2005-01-01

    Using a landmark based approach to Procrustes alignment neglects the functional nature of outlines and surfaces. In order to re-introduce this functional nature into the analysis we will consider alignment of shapes with functional representations. First functional Procrustes analysis of curve sh...

  16. A meta-analysis of self-reported achievement goals and nonself-report performance across three achievement domains (work, sports, and education.

    Directory of Open Access Journals (Sweden)

    Nico W Van Yperen

    Full Text Available During the past three decades, the achievement goal approach to achievement motivation has emerged as an influential area of research, and is dedicated to understanding the reasons behind the individual's drive to achieve competence and performance. However, the current literature on achievement goals is segmented rather than integrated. That is, citations across the three major and distinct achievement domains (work, education, and sports are more the exception than the rule and similarities and differences between findings for the different achievement domains have yet to be tested. The purpose of the present study was to examine the relationships between self-reported achievement goals and nonself-report performance through meta-analysis, and the moderating potential of achievement domain. Identifying achievement domain as moderator improves our understanding to which contexts we can (not generalize conclusions to, it helps to understand seemingly inconsistent findings, and opens avenues for future research on the underlying processes. Because the achievement goal (AG measure used in a study is partially confounded with achievement domain, we examined the moderating role of this variable as well. Our findings suggest that - overall - approach goals (either mastery or performance were associated positively with performance attainment, whereas avoidance goals (either mastery or performance were associated negatively with performance attainment. These relationships were moderated by achievement domain. For example, relative to the education or work domain, in the sports domain, we did not observe negative correlations between avoidance goals and performance. The absence of statistical moderation due to AG measure suggests that the observed moderation of achievement domain cannot be explained by the AG measure utilized. We suggest further steps to integrate the achievement goal literature, and accordingly, to broaden and deepen understanding of

  17. Functional Brain Organization of Working Memory in Adolescents Varies in Relation to Family Income and Academic Achievement

    Science.gov (United States)

    Finn, Amy S.; Minas, Jennifer E.; Leonard, Julia A.; Mackey, Allyson P.; Salvatore, John; Goetz, Calvin; West, Martin R.; Gabrieli, Christopher F. O.; Gabrieli, John D. E.

    2017-01-01

    Working memory (WM) capacity reflects executive functions associated with performance on a wide range of cognitive tasks and education outcomes, including mathematics achievement, and is associated with dorsolateral prefrontal and parietal cortices. Here we asked if family income is associated with variation in the functional brain organization of…

  18. Some Current Themes in Functional Analysis Research.

    Science.gov (United States)

    Vollmer, Timothy R.; Smith, Richard G.

    1996-01-01

    This article discusses clinical application of functional analysis in developmental disabilities, reviewing issues related to treatment logic and development. The article then approaches functional analysis as a research method, reviewing three areas of research: analysis of diverse response topographies, analysis of basic behavioral processes,…

  19. Data Warehouse Designs Achieving ROI with Market Basket Analysis and Time Variance

    CERN Document Server

    Silvers, Fon

    2011-01-01

    Market Basket Analysis (MBA) provides the ability to continually monitor the affinities of a business and can help an organization achieve a key competitive advantage. Time Variant data enables data warehouses to directly associate events in the past with the participants in each individual event. In the past however, the use of these powerful tools in tandem led to performance degradation and resulted in unactionable and even damaging information. Data Warehouse Designs: Achieving ROI with Market Basket Analysis and Time Variance presents an innovative, soup-to-nuts approach that successfully

  20. The Effects of Different Applications on Creativity Regarding Academic Achievement: A Meta-Analysis

    Science.gov (United States)

    Elaldi, Senel; Batdi, Veli

    2016-01-01

    In this study, through a meta-analysis of 20 studies, it is aimed to compare the effectiveness of various forms of learning methods including creativity based learning, problem based learning, and differentiated instruction on creativity in terms of the academic achievement of students and to find out other study characteristics, related to the…

  1. Dynamic Geometry Software Improves Mathematical Achievement: Systematic Review and Meta-Analysis

    Science.gov (United States)

    Chan, Kan Kan; Leung, Siu Wai

    2014-01-01

    Dynamic geometry software (DGS) aims to enhance mathematics education. This systematic review and meta-analysis evaluated the quasi-experimental studies on the effectiveness of DGS-based instruction in improving students' mathematical achievement. Research articles published between 1990 and 2013 were identified from major databases according to a…

  2. A Latent Profile Analysis of Math Achievement, Numerosity, and Math Anxiety in Twins

    Science.gov (United States)

    Hart, Sara A.; Logan, Jessica A. R.; Thompson, Lee; Kovas, Yulia; McLoughlin, Gráinne; Petrill, Stephen A.

    2016-01-01

    Underperformance in math is a problem with increasing prevalence, complex etiology, and severe repercussions. This study examined the etiological heterogeneity of math performance in a sample of 264 pairs of 12-year-old twins assessed on measures of math achievement, numerosity, and math anxiety. Latent profile analysis indicated 5 groupings of…

  3. Social Capital and Adolescents Mathematics Achievement: A Comparative Analysis of Eight European Cities

    Science.gov (United States)

    Gisladottir, Berglind

    2013-01-01

    This study examines the impact of social capital on mathematics achievement in eight European cities. The study draws on data from the 2008 Youth in Europe survey, carried out by the Icelandic Center for Social Research and Analysis. The sample contains responses from 17,312 students in 9th and 10th grade of local secondary schools in the…

  4. Friendship Quality and School Achievement: A Longitudinal Analysis during Primary School

    Science.gov (United States)

    Zucchetti, Giulia; Candela, Filippo; Sacconi, Beatrice; Rabaglietti, Emanuela

    2015-01-01

    This study examined the longitudinal relationship between friendship quality (positive and negative) and school achievement among 228 school-age children (51% girls, M = 8.09, SD = 0.41). A three-wave cross-lagged analysis was used to determine the direction of influence between these domains across school years. Findings revealed that: (a) school…

  5. Blood pressure goal achievement with olmesartan medoxomil-based treatment: additional analysis of the OLMEBEST study

    Science.gov (United States)

    Barrios, Vivencio; Escobar, Carlos; Calderon, Alberto; Böhm, Michael

    2009-01-01

    Aims Guidelines recommend blood pressure (BP) in hypertensive patients should be <140 systolic BP (SBP) and <90 diastolic BP (DBP) mmHg. This analysis assessed goal rate achievement in hypertensive patients receiving olmesartan-based treatment in the OLMEBEST study. Methods Patients with essential hypertension (DBP ≥ 90 mmHg and <110 mmHg) received open-label olmesartan medoxomil 20 mg/day (n = 2306). After 8 weeks, patients with DBP ≥ 90 mmHg (n = 627) were randomized to 4 weeks’ double-blind treatment with olmesartan 40 mg/day monotherapy or olmesartan 20 mg/day plus hydrochlorothiazide (HCTZ) 12.5 mg/day. For this analysis, the numbers and proportions of patients who achieved SBP < 140 mmHg and/or DBP < 90 mmHg at the end of the 4 weeks were calculated. Results In patients who achieved DBP normalization (<90 mmHg) at week 8 (n = 1546) and continued open-label olmesartan 20 mg/day, 66.7% achieved SBP/DBP < 140/90 mmHg at Week 12. In patients who did not achieve DBP normalization at Week 8, 26.8% of those randomized to olmesartan 40 mg/day and 42.5% of those randomized to olmesartan 20 mg/day plus HCTZ 12.5 mg/day achieved a SBP/DBP < 140/90 mmHg at Week 12. Conclusion Olmesartan 40 mg/day and olmesartan 20 mg/day plus HCTZ 12.5 mg/day allow substantial proportions of patients to achieve BP goals. PMID:19756164

  6. The Effectiveness of Multiple Intelligence Applications on Academic Achievement: A Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Eyüp Yurt

    2015-05-01

    Full Text Available The purpose of this study was to examine the effectiveness of multiple intelligence applications on academic achievement in Turkey. Accordingly, findings of independent research studies aimed to find out effectiveness of multiple intelligence applications are gathered in a meta-analysis. Total of 71 studies, 66 dissertations and 7 articles were included in the meta-analysis meeting the inclusion criteria. Meta-analysis calculations resulted that the multiple intelligence applications have a large and positive effect on academic achievement. It was also revealed that the effect of multiple intelligence applications vary by application period. Thus, as the application period increases, the effect of multiple intelligence application also increases. On the other side, effectiveness of the applications does not vary by; the type of the course, level of the class and the type of the research. Some suggestions made according to the research findings.

  7. The Relationship of Cognitive and Executive Functioning with Achievement in Gifted Kindergarten Children

    Science.gov (United States)

    Hernández Finch, Maria E.; Speirs Neumeister, Kristie L.; Burney, Virginia H.; Cook, Audra L.

    2014-01-01

    This study provides baseline data to assist researchers in conducting future studies exploring the developmental trajectories of young gifted learners on measures of cognitive ability and achievement. The study includes common neuropsychological tests associated with preliteracy and the early-reading process as well as markers for inattention and…

  8. The Relationship between Frequency and Functionality of Professional Learning Communities to Student Achievement

    Science.gov (United States)

    Linton, Jack, Jr.

    2014-01-01

    The ultimate goal of teacher professional development is to improve student achievement by improving teacher practices. To that end, the literature and research supports the development of professional learning communities as one of the most effective ways to accomplish that goal. Therefore, the research questions addressed in this study were: (a)…

  9. Basic methods of linear functional analysis

    CERN Document Server

    Pryce, John D

    2011-01-01

    Introduction to the themes of mathematical analysis, geared toward advanced undergraduate and graduate students. Topics include operators, function spaces, Hilbert spaces, and elementary Fourier analysis. Numerous exercises and worked examples.1973 edition.

  10. An analysis of factors that affect public and private school science achievement

    Science.gov (United States)

    Staver, John R.; Walberg, Herbert J.

    Data on 30,030 sophomores in the High School and Beyond project were analyzed to test the private school superiority hypothesis for science achievement. The supposition that private schools are superior to public schools in producing science achievement is rejected on the basis of the present analysis. Major differences in science achievement between public and private schools appear attributable to relatively fixed characteristics of students and to their experiences beyond the school environment, rather than to factors easily alterable by educators. The authors point out and discuss the value of homework, the problem of excessive television viewing, the influence of parental involvement in education, and the effect of the amount of academic classes taken.Received: 5 September 1985

  11. Achievement goals and autonomy: how person--context interactions predict effective functioning and well-being during a career transition.

    Science.gov (United States)

    Heidemeier, Heike; Wiese, Bettina S

    2014-01-01

    This study examined how achievement goals interact with autonomy to explain mastery of a challenging career transition. In a sample of women who were returning from maternity leave, we examined how autonomy interacted with achievement goals to explain two types of outcomes: effective functioning (i.e., self-rated work adjustment, coworker-rated work adjustment, and coworker-rated learning competence) and well-being at work (i.e., positive affect and life satisfaction). In a longitudinal design (249 employees), we found that achievement goals and autonomy had direct effects on successful return to work. Moreover, maladaptive motivational states hindered the effective use of workplace resources: Autonomy moderated the consequences associated with performance-prove and -avoidance goals. Among those who adopted performance-prove goals, autonomy improved work adjustment and learning. However, women who adopted performance-avoidance goals experienced a trade-off between effective functioning and well-being, when equipped with high autonomy.

  12. LD Status and Achievement: Confounding Variables in the Study of Children's Social Status, Self-Esteem, and Behavioral Functioning.

    Science.gov (United States)

    La Greca, Annette M.; Stone, Wendy L.

    1990-01-01

    Compared to classmates with low and average reading achievement, 32 intermediate-grade students with learning disabilities (LD) had lower peer acceptance, lower feelings of self-worth, fewer positive nominations, and more negative self-perceptions regarding social acceptance. Different patterns of social and behavioral functioning distinguished LD…

  13. Do Children's Executive Functions Account for Associations between Early Autonomy-Supportive Parenting and Achievement through High School?

    Science.gov (United States)

    Bindman, Samantha W.; Pomerantz, Eva M.; Roisman, Glenn I.

    2015-01-01

    This study evaluated whether the positive association between early autonomy-supportive parenting and children's subsequent achievement is mediated by children's executive functions. Using observations of mothers' parenting from the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development (N…

  14. The Longitudinal Process of Early Parent Involvement on Student Achievement: A Path Analysis.

    Science.gov (United States)

    Hayakawa, Momoko; Englund, Michelle M; Warner-Richter, Mallory N; Reynolds, Arthur J

    2013-01-01

    This longitudinal study investigated the process whereby early parent involvement in preschool effects student achievement from kindergarten through 6(th) grade. Participants were 1,539 low-income, mainly African American children and their mothers, in the Chicago Longitudinal Study. Program children (N = 989) received one or two years of the Child-Parent Center (CPC) program - a preschool intervention that strongly promoted parents' development of parent involvement skills within the school and at home. Children from similar backgrounds who did not attend the CPC, but participated in available local resources (e.g. day care), were obtained as a comparison group (N = 550). Path analysis revealed an interactive process between parent involvement, academic achievement, and children's motivation. Early parent involvement directly influenced kindergarten achievement, which in turn influenced first grade student motivation. Highly motivated children then encouraged parents to continue involvement. The cyclic nature of this process across elementary school was observed. The model accounted for 61% of the variance in 6(th) grade achievement. Findings suggest that early parent involvement promoted in the CPC program, sets the stage for subsequent parent involvement, student motivation, and academic achievement throughout early and middle childhood.

  15. How Socioeconomic Status, Executive Functioning and Verbal Interactions Contribute to Early Academic Achievement in Chinese Children

    Science.gov (United States)

    Chung, Kevin K. H.; Liu, Hongyun; McBride, Catherine; Wong, Anita M. -Y.; Lo, Jason C. M.

    2017-01-01

    The present study investigated the relative importance of executive functioning, parent-child verbal interactions, phonological awareness and visual skills on reading and mathematics for Chinese children from low-versus middle-socio economic status (SES) backgrounds. A total of 199 kindergarten children were assessed on executive functioning,…

  16. Integrated Treatment to Achieve Functional Recovery for First-Episode Psychosis

    Directory of Open Access Journals (Sweden)

    Marcelo Valencia

    2012-01-01

    Full Text Available This study describes an integrated treatment approach that was implemented to enhance functional recovery in first-episode psychotic patients. Patients were randomized to two treatment conditions: either to an integrated treatment approach: pharmacotherapy, psychosocial treatment, and psychoeducation (experimental group: N=39 or to medication alone (control group: N=34. Patients were evaluated at baseline and after one year of treatment. Functional recovery was assessed according to symptomatic and functional remission. At the end of treatment, experimental patients showed a 94.9% of symptomatic remission compared to 58.8% of the control group. Functional remission was 56.4% for the experimental group and 3.6% for the control group, while 56.4% of the experimental group met both symptomatic and functional remission criteria and were considered recovered compared to 2.9% of the control group.

  17. Association of creative achievement with cognitive flexibility by a combined voxel-based morphometry and resting-state functional connectivity study.

    Science.gov (United States)

    Chen, Qunlin; Yang, Wenjing; Li, Wenfu; Wei, Dongtao; Li, Haijiang; Lei, Qiao; Zhang, Qinglin; Qiu, Jiang

    2014-11-15

    Although researchers generally concur that creativity involves the production of novel and useful products, the neural basis of creativity remains elusive due to the complexity of the cognitive processes involved. Recent studies have shown that highly creative individuals displayed more cognitive flexibility. However, direct evidence supporting the relationship between creativity and cognitive flexibility has rarely been investigated using both structural and functional neuroimaging techniques. We used a combined voxel-based morphometry and resting-state functional connectivity (rsFC) analysis to investigate the relationship between individual creativity ability assessed by the creative achievement questionnaire (CAQ), and regional gray matter volume (GMV), as well as intrinsic functional connectivity. Results showed that CAQ scores negatively correlated with GMV in the rostral anterior cingulate cortex (ACC) and the bilateral dorsal ACC (dACC) extending to supplementary motor area, but positively correlated with GMV in the bilateral superior frontal gyrus and ventral medial prefrontal cortex (vmPFC). Further functional connectivity analysis revealed that higher creative achievement was inversely associated with the strength of rsFC between the dACC and medial superior frontal gyrus (mSFG), right middle frontal gyrus, and left orbito-frontal insula. Moreover, the association between the dACC-mSFG connectivity and CAQ scores was mediated by cognitive flexibility, assessed by a task-switching paradigm. These findings indicate that individual differences in creative achievement are associated with both brain structure and corresponding intrinsic functional connectivity involved in cognitive flexibility and deliberate creative processing. Furthermore, dACC-mSFG connectivity may affect creative achievement through its impact on cognitive flexibility.

  18. Pineal function: impact of microarray analysis

    DEFF Research Database (Denmark)

    Klein, David C; Bailey, Michael J; Carter, David A

    2009-01-01

    Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity...... foundation that microarray analysis has provided will broadly support future research on pineal function....

  19. Basic Functional Analysis Puzzles of Spectral Flow

    DEFF Research Database (Denmark)

    Booss-Bavnbek, Bernhelm

    2011-01-01

    We explain an array of basic functional analysis puzzles on the way to general spectral flow formulae and indicate a direction of future topological research for dealing with these puzzles.......We explain an array of basic functional analysis puzzles on the way to general spectral flow formulae and indicate a direction of future topological research for dealing with these puzzles....

  20. Differential analysis of matrix convex functions II

    DEFF Research Database (Denmark)

    Hansen, Frank; Tomiyama, Jun

    2009-01-01

    We continue the analysis in [F. Hansen, and J. Tomiyama, Differential analysis of matrix convex functions. Linear Algebra Appl., 420:102--116, 2007] of matrix convex functions of a fixed order defined in a real interval by differential methods as opposed to the characterization in terms of divide...

  1. Functional analysis in MR urography - made simple

    Energy Technology Data Exchange (ETDEWEB)

    Khrichenko, Dmitry; Darge, Kassa [Children' s Hospital of Philadelphia, Department of Radiology, Philadelphia, PA (United States)

    2010-02-15

    MR urography (MRU) has proved to be a most advantageous imaging modality of the urinary tract in children, providing one-stop comprehensive morphological and functional information, without the utilization of ionizing radiation. The functional analysis of the MRU scan still requires external post-processing using relatively complex software. This has proved to be a limiting factor in widespread routine implementation of MRU functional analysis and use of MRU functional parameters similar to nuclear medicine. We present software, developed in a pediatric radiology department, that not only enables comprehensive automated functional analysis, but is also very user-friendly, fast, easily operated by the average radiologist or MR technician and freely downloadable Virtual Machine is required for the installation, which is obtained at no charge. The analysis software, known as ''CHOP-fMRU,'' has the potential to help overcome the obstacles to widespread use of functional MRU in children. (orig.)

  2. Linear functional analysis for scientists and engineers

    CERN Document Server

    Limaye, Balmohan V

    2016-01-01

    This book provides a concise and meticulous introduction to functional analysis. Since the topic draws heavily on the interplay between the algebraic structure of a linear space and the distance structure of a metric space, functional analysis is increasingly gaining the attention of not only mathematicians but also scientists and engineers. The purpose of the text is to present the basic aspects of functional analysis to this varied audience, keeping in mind the considerations of applicability. A novelty of this book is the inclusion of a result by Zabreiko, which states that every countably subadditive seminorm on a Banach space is continuous. Several major theorems in functional analysis are easy consequences of this result. The entire book can be used as a textbook for an introductory course in functional analysis without having to make any specific selection from the topics presented here. Basic notions in the setting of a metric space are defined in terms of sequences. These include total boundedness, c...

  3. AUDIT FUNCTION ROLE IN ACHIEVING AN EFFICIENT CORPORATE GOVERNANCE – CONCEPTUAL MODEL PROPOSAL

    OpenAIRE

    Melinda Timea Fülöp

    2013-01-01

    Nowadays corporate governance plays an important role in decisions making processes, which represents a relatively new approach for both Romanian scientific studies and practice. As a consequence we consider the increased attention given to corporate governance to be crucial, especially addressing the role of the audit function and the importance of the corporate governance code. Audit function is of particular practical importance in corporate governance, therefore we decided ...

  4. Functional linear regression via canonical analysis

    CERN Document Server

    He, Guozhong; Wang, Jane-Ling; Yang, Wenjing; 10.3150/09-BEJ228

    2011-01-01

    We study regression models for the situation where both dependent and independent variables are square-integrable stochastic processes. Questions concerning the definition and existence of the corresponding functional linear regression models and some basic properties are explored for this situation. We derive a representation of the regression parameter function in terms of the canonical components of the processes involved. This representation establishes a connection between functional regression and functional canonical analysis and suggests alternative approaches for the implementation of functional linear regression analysis. A specific procedure for the estimation of the regression parameter function using canonical expansions is proposed and compared with an established functional principal component regression approach. As an example of an application, we present an analysis of mortality data for cohorts of medflies, obtained in experimental studies of aging and longevity.

  5. Qualitative content analysis in nursing research: concepts, procedures and measures to achieve trustworthiness.

    Science.gov (United States)

    Graneheim, U H; Lundman, B

    2004-02-01

    Qualitative content analysis as described in published literature shows conflicting opinions and unsolved issues regarding meaning and use of concepts, procedures and interpretation. This paper provides an overview of important concepts (manifest and latent content, unit of analysis, meaning unit, condensation, abstraction, content area, code, category and theme) related to qualitative content analysis; illustrates the use of concepts related to the research procedure; and proposes measures to achieve trustworthiness (credibility, dependability and transferability) throughout the steps of the research procedure. Interpretation in qualitative content analysis is discussed in light of Watzlawick et al.'s [Pragmatics of Human Communication. A Study of Interactional Patterns, Pathologies and Paradoxes. W.W. Norton & Company, New York, London] theory of communication.

  6. Blood pressure goal achievement with olmesartan medoxomil-based treatment: additional analysis of the OLMEBEST study

    Directory of Open Access Journals (Sweden)

    Vivencio Barrios

    2009-08-01

    Full Text Available Vivencio Barrios1, Carlos Escobar1, Alberto Calderon2, Michael Böhm31Department of Cardiology, Hospital Ramón y Cajal, Madrid, Spain; 2Primary Care Center Rosa de Luxemburgo, Madrid, Spain; 3Klinik für Innere Medizin III, Universitätsklinikum des Saarlandes, Homburg/Saar, GermanyAims: Guidelines recommend blood pressure (BP in hypertensive patients should be <140 systolic BP (SBP and <90 diastolic BP (DBP mmHg. This analysis assessed goal rate achievement in hypertensive patients receiving olmesartan-based treatment in the OLMEBEST study.Methods: Patients with essential hypertension (DBP ≥ 90 mmHg and <110 mmHg received open-label olmesartan medoxomil 20 mg/day (n = 2306. After 8 weeks, patients with DBP ≥ 90 mmHg (n = 627 were randomized to 4 weeks’ double-blind treatment with olmesartan 40 mg/day monotherapy or olmesartan 20 mg/day plus hydrochlorothiazide (HCTZ 12.5 mg/day. For this analysis, the numbers and proportions of patients who achieved SBP < 140 mmHg and/or DBP < 90 mmHg at the end of the 4 weeks were calculated.Results: In patients who achieved DBP normalization (<90 mmHg at week 8 (n = 1546 and continued open-label olmesartan 20 mg/day, 66.7% achieved SBP/DBP < 140/90 mmHg at Week 12. In patients who did not achieve DBP normalization at Week 8, 26.8% of those randomized to olmesartan 40 mg/day and 42.5% of those randomized to olmesartan 20 mg/day plus HCTZ 12.5 mg/day achieved a SBP/DBP < 140/90 mmHg at Week 12.Conclusion: Olmesartan 40 mg/day and olmesartan 20 mg/day plus HCTZ 12.5 mg/day allow substantial proportions of patients to achieve BP goals.Keywords: olmesartan medoxomil, hypertension, angiotensin II receptor blocker, goal rates, hydrochlorothiazide

  7. Leukemia-induced phenotypic and functional defects in natural killer cells predict failure to achieve remission in acute myeloid leukemia.

    Science.gov (United States)

    Stringaris, Kate; Sekine, Takuya; Khoder, Ahmad; Alsuliman, Abdullah; Razzaghi, Bonnie; Sargeant, Ruhena; Pavlu, Jiri; Brisley, Gill; de Lavallade, Hugues; Sarvaria, Anushruthi; Marin, David; Mielke, Stephan; Apperley, Jane F; Shpall, Elizabeth J; Barrett, A John; Rezvani, Katayoun

    2014-05-01

    The majority of patients with acute myeloid leukemia will relapse, and older patients often fail to achieve remission with induction chemotherapy. We explored the possibility that leukemic suppression of innate immunity might contribute to treatment failure. Natural killer cell phenotype and function was measured in 32 consecutive acute myeloid leukemia patients at presentation, including 12 achieving complete remission. Compared to 15 healthy age-matched controls, natural killer cells from acute myeloid leukemia patients were abnormal at presentation, with downregulation of the activating receptor NKp46 (P=0.007) and upregulation of the inhibitory receptor NKG2A (P=0.04). Natural killer cells from acute myeloid leukemia patients had impaired effector function against autologous blasts and K562 targets, with significantly reduced CD107a degranulation, TNF-α and IFN-γ production. Failure to achieve remission was associated with NKG2A overexpression and reduced TNF-α production. These phenotypic and functional abnormalities were partially restored in the 12 patients achieving remission. In vitro co-incubation of acute myeloid leukemia blasts with natural killer cells from healthy donors induced significant impairment in natural killer cell TNF-α and IFN-γ production (P=0.02 and P=0.01, respectively) against K562 targets and a trend to reduced CD107a degranulation (P=0.07). Under transwell conditions, the inhibitory effect of AML blasts on NK cytotoxicity and effector function was still present, and this inhibitory effect was primarily mediated by IL-10. These results suggest that acute myeloid leukemia blasts induce long-lasting changes in natural killer cells, impairing their effector function and reducing the competence of the innate immune system, favoring leukemia survival.

  8. Construction and analysis of cryptographic functions

    CERN Document Server

    Budaghyan, Lilya

    2015-01-01

    This book covers novel research on construction and analysis of optimal cryptographic functions such as almost perfect nonlinear (APN), almost bent (AB), planar and bent functions. These functions have optimal resistance to linear and/or differential attacks, which are the two most powerful attacks on symmetric cryptosystems. Besides cryptographic applications, these functions are significant in many branches of mathematics and information theory including coding theory, combinatorics, commutative algebra, finite geometry, sequence design and quantum information theory. The author analyzes equ

  9. Multivariate analysis of functional metagenomes

    Directory of Open Access Journals (Sweden)

    Elizabeth A. Dinsdale

    2013-04-01

    Full Text Available Metagenomics is a primary tool for the description of microbial and viral communities. The sheer magnitude of the data generated in each metagenome makes identifying key differences in the function and taxonomy between communities difficult to elucidate. Here we discuss the application of seven different data mining and statistical analyses by comparing and contrasting the metabolic functions of 212 microbial metagenomes within and between 10 environments. Not all approaches are appropriate for all questions, and researchers should decide which approach addresses their questions. This work demonstrated the use of each approach: for example, random forests provided a robust and enlightening description of both the clustering of metagenomes and the metabolic processes that were important in separating microbial communities from different environments. All analyses identified that the presence of phage genes within the microbial community was a predictor of whether the microbial community was host associated or free living. Several analyses identified the subtle differences that occur with environments, such as those seen in different regions of the marine environment.

  10. Executive Functioning Predicts Academic Achievement in Middle School: A Four-Year Longitudinal Study

    Science.gov (United States)

    Samuels, William Ellery; Tournaki, Nelly; Blackman, Sheldon; Zilinski, Christopher

    2016-01-01

    Executive functioning (EF) is a strong predictor of children's and adolescents' academic performance. Although research indicates that EF can increase during childhood and adolescence, few studies have tracked the effect of EF on academic performance throughout the middle school grades. EF was measured at the end of Grades 6-9 through 21 teachers'…

  11. Cognitive Functioning and Academic Achievement in Children with Insulin-Dependent Diabetes Mellitus (IDDM).

    Science.gov (United States)

    Holmes, Clarissa S.; And Others

    1995-01-01

    Consistent evidence relates insulin dependent diabetes mellitus (IDDM) to lower intellectual functioning in children, although performance is still in the average range. Children with IDDM have received specialized classroom assistance at school. Boys with diabetes appear at greater risk for learning problems than girls. Evidence suggests both…

  12. Differences in Academic Achievement among Texas High School Students as a Function of Music Enrollment

    Science.gov (United States)

    Horton, Robert Wayne

    2012-01-01

    Purpose: The purpose of this study was to examine the score differences on the Texas Academic Knowledge and Skills (TAKS) Reading and Mathematics measures among students in Grades 10 and 11 as a function of music enrollment. Specifically, gender, ethnicity, socioeconomic status, and enrollment in choir, band, or orchestra or no music enrollment…

  13. Impact of Attention Training on Academic Achievement, Executive Functioning, and Behavior: A Randomized Controlled Trial

    Science.gov (United States)

    Kirk, Hannah; Gray, Kylie; Ellis, Kirsten; Taffe, John; Cornish, Kim

    2017-01-01

    Children with intellectual and developmental disabilities (IDD) experience significant difficulties in attention, learning, executive functions, and behavioral regulation. Emerging evidence suggests that computerized cognitive training may remediate these impairments. In a double blind controlled trial, 76 children with IDD (4-11 years) were…

  14. Differences in Academic Achievement among Texas High School Students as a Function of Music Enrollment

    Science.gov (United States)

    Horton, Robert Wayne

    2012-01-01

    Purpose: The purpose of this study was to examine the score differences on the Texas Academic Knowledge and Skills (TAKS) Reading and Mathematics measures among students in Grades 10 and 11 as a function of music enrollment. Specifically, gender, ethnicity, socioeconomic status, and enrollment in choir, band, or orchestra or no music enrollment…

  15. Executive Function and Mathematics Achievement: Are Effects Construct- and Time-General or Specific?

    Science.gov (United States)

    Duncan, Robert; Nguyen, Tutrang; Miao, Alicia; McClelland, Megan; Bailey, Drew

    2016-01-01

    Executive function (EF) is considered a set of interrelated cognitive processes, including inhibitory control, working memory, and attentional shifting, that are connected to the development of the prefrontal cortex and contribute to children's problem solving skills and self regulatory behavior (Best & Miller, 2010; Garon, Bryson, &…

  16. Behavioral Self-Regulation and Executive Function Both Predict Visuomotor Skills and Early Academic Achievement

    Science.gov (United States)

    Becker, Derek R.; Miao, Alicia; Duncan, Robert; McClelland, Megan M.

    2014-01-01

    The present study explored direct and interactive effects between behavioral self-regulation (SR) and two measures of executive function (EF, inhibitory control and working memory), with a fine motor measure tapping visuomotor skills (VMS) in a sample of 127 prekindergarten and kindergarten children. It also examined the relative contribution of…

  17. Nutritional and socio-economic determinants of cognitive function and educational achievement of Aboriginal schoolchildren in rural Malaysia.

    Science.gov (United States)

    Al-Mekhlafi, Hesham M; Mahdy, Mohammed A; Sallam, Atiya A; Ariffin, W A; Al-Mekhlafi, Abdulsalam M; Amran, Adel A; Surin, Johari

    2011-10-01

    A community-based cross-sectional study was carried out among Aboriginal schoolchildren aged 7-12 years living in remote areas in Pos Betau, Pahang, Malaysia to investigate the potential determinants influencing the cognitive function and educational achievement of these children. Cognitive function was measured by intelligence quotient (IQ), while examination scores of selected school subjects were used in assessing educational achievement. Blood samples were collected to assess serum Fe status. All children were screened for soil-transmitted helminthes. Demographic and socio-economic data were collected using pre-tested questionnaires. Almost two-thirds (67·6 %) of the subjects had poor IQ and most of them (72·6 %) had insufficient educational achievement. Output of the stepwise multiple regression model showed that poor IQ was significantly associated with low household income which contributed the most to the regression variance (r2 0·059; P = 0·020). Low maternal education was also identified as a significant predictor of low IQ scores (r2 0·042; P = 0·043). With educational achievement, Fe-deficiency anaemia (IDA) was the only variable to show significant association (r2 0·025; P = 0·015). In conclusion, the cognitive function and educational achievement of Aboriginal schoolchildren are poor and influenced by household income, maternal education and IDA. Thus, effective and integrated measures to improve the nutritional and socio-economic status of rural children would have a pronounced positive effect on their education.

  18. Longer term improvement in neurocognitive functioning and affective distress among methamphetamine users who achieve stable abstinence.

    Science.gov (United States)

    Iudicello, Jennifer E; Woods, Steven P; Vigil, Ofilio; Scott, J Cobb; Cherner, Mariana; Heaton, Robert K; Atkinson, J Hampton; Grant, Igor

    2010-08-01

    Chronic use of methamphetamine (MA) is associated with neuropsychological dysfunction and affective distress. Some normalization of function has been reported after abstinence, but little in the way of data is available on the possible added benefits of long-term sobriety. To address this, we performed detailed neuropsychological and affective evaluations in 83 MA-dependent individuals at a baseline visit and following an average one-year interval period. Among the 83 MA-dependent participants, 25 remained abstinent, and 58 used MA at least once during the interval period. A total of 38 non-MA-addicted, demographically matched healthy comparison (i.e., HC) participants were also examined. At baseline, both MA-dependent participants who were able to maintain abstinence and those who were not performed significantly worse than the healthy comparison subjects on global neuropsychological functioning and were significantly more distressed. At the one-year follow-up, both the long-term abstainers and healthy comparison groups showed comparable global neuropsychological performance and affective distress levels, whereas the MA-dependent group who continued to use MA were worse than the comparison participants in terms of global neuropsychological functioning and affective distress. An interaction was observed between neuropsychological impairment at baseline, MA abstinence, and cognitive improvement, with abstinent MA-dependent participants who were neuropsychologically impaired at baseline demonstrating significantly and disproportionately greater improvement in processing speed and slightly greater improvement in motor abilities than the other participants. These results suggest partial recovery of neuropsychological functioning and improvement in affective distress upon sustained abstinence from MA that may extend beyond a year or more.

  19. Early math achievement and functional connectivity in the fronto-parietal network.

    Science.gov (United States)

    Emerson, Robert W; Cantlon, Jessica F

    2012-02-15

    In this study we test the hypothesis that the functional connectivity of the frontal and parietal regions that children recruit during a basic numerical task (matching Arabic numerals to arrays of dots) is predictive of their math test scores (TEMA-3; Ginsburg, 2003). Specifically, we tested 4-11-year-old children on a matching task during fMRI to localize a fronto-parietal network that responds more strongly during numerical matching than matching faces, words, or shapes. We then tested the functional connectivity between those regions during an independent task: natural viewing of an educational video that included math topics. Using this novel natural viewing method, we found that the connectivity between frontal and parietal regions during task-independent free-viewing of educational material is correlated with children's basic number matching ability, as well as their scores on the standardized test of mathematical ability (the TEMA). The correlation between children's mathematics scores and fronto-parietal connectivity is math-specific in the sense that it is independent of children's verbal IQ scores. Moreover, a control network, selective for faces, showed no correlation with mathematics performance. Finally, brain regions that correlate with subjects' overall response times in the matching task do not account for our number- and math-related effects. We suggest that the functional intersection of number-related frontal and parietal regions is math-specific. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. Functional joint regeneration is achieved using reintegration mechanism in Xenopus laevis.

    Science.gov (United States)

    Tsutsumi, Rio; Yamada, Shigehito; Agata, Kiyokazu

    2016-02-01

    A functional joint requires integration of multiple tissues: the apposing skeletal elements should form an interlocking structure, and muscles should insert into skeletal tissues via tendons across the joint. Whereas newts can regenerate functional joints after amputation, Xenopus laevis regenerates a cartilaginous rod without joints, a "spike." Previously we reported that the reintegration mechanism between the remaining and regenerated tissues has a significant effect on regenerating joint morphogenesis during elbow joint regeneration in newt. Based on this insight into the importance of reintegration, we amputated frogs' limbs at the elbow joint and found that frogs could regenerate a functional elbow joint between the remaining tissues and regenerated spike. During regeneration, the regenerating cartilage was partially connected to the remaining articular cartilage to reform the interlocking structure of the elbow joint at the proximal end of the spike. Furthermore, the muscles of the remaining part inserted into the regenerated spike cartilage via tendons. This study might open up an avenue for analyzing molecular and cellular mechanisms of joint regeneration using Xenopus.

  1. Deficits in cognitive function and achievement in Mexican first-graders with low blood lead concentrations.

    Science.gov (United States)

    Kordas, Katarzyna; Canfield, Richard L; López, Patricia; Rosado, Jorge L; Vargas, Gonzalo García; Cebrián, Mariano E; Rico, Javier Alatorre; Ronquillo, Dolores; Stoltzfus, Rebecca J

    2006-03-01

    Elevated blood lead levels in children are associated with lower scores on tests of cognitive functioning. Recent studies have reported inverse relations between lifetime exposure and intellectual functioning at blood lead concentrations below 10 microg/dL, the Centers for Disease Control and Prevention's (CDC) level of concern. We report associations between blood lead and cognitive performance for first-grade Mexican children living near a metal foundry. Using a cross-sectional design, we examined the relation between children's concurrent blood lead concentrations (mean (SD) 11.4 microg/dL (6.1)) and their performance on 14 tests of global or specific cognitive functions. The blood lead-cognition relations were modeled using both linear and nonlinear methods. After adjustment for covariates, a higher blood lead level was associated with poorer cognitive performance on several cognitive tests. Segmented linear regressions revealed significant effects of lead but only for the segments defined by a concurrent blood lead concentration below 10-14 microg/dL. One implication of these findings is that at the age of 7 years, even in the absence of information on lead exposure in infancy and early childhood, a test result with blood lead < 10 microg/dL should not be considered safe. Together with other recent findings, these results add to the empirical base of support available for evaluating the adequacy of current screening guidelines and for motivating efforts at primary prevention of childhood lead exposure.

  2. Function analysis of unknown genes

    DEFF Research Database (Denmark)

    Rogowska-Wrzesinska, A.

    2002-01-01

    leading to decreased growth rate, decreased glucose metabolism, decreased amino acid and protein synthesis and increased protein degradation. Some of these responses define a new type of stress that results from changes in the internal cell environment by overexpression of a membrane protein. Chapter 5...... that have been post-translationally modified by N- or C-terminal truncation and we show that this protein processing is not random and shows a specific pattern for a given yeast strain. Chapter 7 illustrates the construction of yeast proteome database and its potential application in characterising yeast...... analysis is a powerful tool to study yeast proteome and the complex proteome database gives a broad view on the molecular cell biology of yeast. The global database approach allows combining proteome data from different mutants and experiment conditions (e.g. heat stress, phosphate labelling, N...

  3. Static analysis of function calls in Erlang

    Directory of Open Access Journals (Sweden)

    Dániel Horpácsi

    2013-06-01

    Full Text Available Functions and their relations can affect numerous properties and metrics of a functional program. To identify and represent the functions and their calling connections, software analysers commonly apply semantic function analysis, which derives the static call graph of the program, based on its source code. Function calls however may be dynamic and complex, making it difficult to statically identify the callee. Dynamic calls are determined just at run-time, static analysis therefore cannot be expected to fully identify every call. Nevertheless, by utilising the results of a properly performed data-flow analysis as well as taking ambiguous references into account, numerous dynamic calls are discoverable and representable. We consider cases where the identifiers of the callee are statically determined, but they flow into the call expression from a different program point, and also, we manage to handle function calls whose identifiers are not fully identifiable at compile-time. By utilising the improved reference analysis, we extend the static call graph with various information about dynamic function calls. We investigate such a function call analysis in the programming language Erlang.

  4. Examining the relation between ratings of executive functioning and academic achievement: findings from a cross-cultural study.

    Science.gov (United States)

    Thorell, Lisa B; Veleiro, Alberto; Siu, Angela F Y; Mohammadi, Hiwa

    2013-01-01

    The present study investigated the relation between academic performance and ratings of executive functioning in children aged 6-11 from four countries: Sweden, Spain, Iran, and China. Ratings of executive functioning were made by both parents and teachers using the Childhood Executive Functioning Inventory (CHEXI). The results showed that the Chinese sample was generally rated as having more executive deficits compared to the other samples. The finding that executive functioning deficits are exacerbated in China is most likely the result of cultural biases. Boys were generally rated as having poorer executive functioning compared to girls, except in Iran where parents, but not teachers, rated girls as having poorer executive functioning compared to boys. However, this opposite pattern of results found for Iran is not likely to reflect true gender differences in executive functioning. Despite some differences in the levels of executive functioning across countries, both the inhibition and working memory subscales of the CHEXI were related to academic achievement in all four countries, except for CHEXI parent ratings in China. Altogether, the results indicate that the CHEXI may be used as a screening measure for early academic difficulties, although cultural biases clearly have to be taken into consideration.

  5. The relationship between functional movement analysis and ...

    African Journals Online (AJOL)

    ... functional movement analysis and lowerbody injury rates in adolescent female football players. ... South African Journal of Sports Medicine ... suggestions that it is essential to develop a prevention strategy to measure trauma and recovery.

  6. The Functional Methods of Discourse Analysis

    Institute of Scientific and Technical Information of China (English)

    覃卓敏

    2008-01-01

    From the macroscopic angle of function, methods of discourse analysis are clarified to find out two important methods in pragmatics and through which will better used in the understanding of discourse.

  7. Pathway-Based Functional Analysis of Metagenomes

    Science.gov (United States)

    Bercovici, Sivan; Sharon, Itai; Pinter, Ron Y.; Shlomi, Tomer

    Metagenomic data enables the study of microbes and viruses through their DNA as retrieved directly from the environment in which they live. Functional analysis of metagenomes explores the abundance of gene families, pathways, and systems, rather than their taxonomy. Through such analysis researchers are able to identify those functional capabilities most important to organisms in the examined environment. Recently, a statistical framework for the functional analysis of metagenomes was described that focuses on gene families. Here we describe two pathway level computational models for functional analysis that take into account important, yet unaddressed issues such as pathway size, gene length and overlap in gene content among pathways. We test our models over carefully designed simulated data and propose novel approaches for performance evaluation. Our models significantly improve over current approach with respect to pathway ranking and the computations of relative abundance of pathways in environments.

  8. Functional Data Analysis Applied in Chemometrics

    DEFF Research Database (Denmark)

    Muller, Martha

    In this thesis we explore the use of functional data analysis as a method to analyse chemometric data, more specically spectral data in metabolomics. Functional data analysis is a vibrant eld in statistics. It has been rapidly expanding in both methodology and applications since it was made well...... known by Ramsay & Silverman's monograph in 1997. In functional data analysis, the data are curves instead of data points. Each curve is measured at discrete points along a continuum, for example, time or frequency. It is assumed that the underlying process generating the curves is smooth......, but it is not assumed that the adjacent points measured along the continuum are independent. Standard chemometric methods originate from the eld of multivariate analysis, where variables are often assumed to be independent. Typically these methods do not explore the rich functional nature of spectral data. Metabolomics...

  9. Formulating effective policy: Some functions of language in achieving or hindering democratic change

    Directory of Open Access Journals (Sweden)

    Stanley G M Ridge

    2008-08-01

    Full Text Available Using examples from education and language policy, this paper explores the implications of certain ways of using language for realising policy goals. Of course, no policy is inherently good, and the best-formulated policy can be turned to bad account. The paper demonstrates, first, that what seems like reactionwy policy can be animated by progressive ideals, and supposedly progressive policy can be used to liberate or oppress depending on the larger social situation. The key issues for this paper is more practical. Well-formulated policy is conductive to success, and bad formulation of policy can impede the achievement of goals and open the way for unintended consequences.Two problems of formulation are dealt with. First, shoddy expression and conceptualisationis shown to create difficulties in some Outcomes Based Education policy documents. The second problem is binary discourse. It is far more insidious and pervasive. The paper demonstrates how binary discourse creates major impediments to implementation in key policy documents relating to education and to language. The difficulties are analysed in some detail. Voorbeelde van die onderwys- en taalbeleid word in hierdie artikel gebruik om die rol van taal in die realisering van die gestelde ideale te verken. Dit blyk dat beleid nie inherent goed is nie. Bleeid wat reaksioner Iyk. kan verlewendig word deur progressiewe ideale, en veronderstelde progressiewe beleid kan, afhangend van die breër sosiale situasie, gehruik word om te bevry of te onderdruk. Beleid wat swak geformuleer is, kan weer die hereiking van beleidsdoelstellings belemme. Oor die algemeen veroorsaak slordige uitdrukking en konseptualisering probleme in sommige beleidsdokumente oor Uitkomsbaseerde Onderwys. Binêre diskoers in die besonder veroorsaakwesenlikebelemmeringe ten opsigtevandieimplementeringvan kernbeliedsdokumenteoor onderwys en taal. Hierdie prohleme word gedeeltelik geanliseer.

  10. The developments and achievements of endoscopic surgery, robotic surgery and function-preserving surgery.

    Science.gov (United States)

    Yoshida, Masashi; Furukawa, Toshiharu; Morikawa, Yasuhide; Kitagawa, Yuko; Kitajima, Masaki

    2010-09-01

    The breakthrough in laparoscopic surgery has been the development of a charge-coupled device camera system and Mouret performing cholecystectomy in 1987. The short-term benefits of laparoscopic surgery are widely accepted and the long-term benefit of less incidence of bowel obstruction can be expected. The important developments have been the articulating instrumentation via new laparoscopic access ports. Since 2007, single-incision laparoscopic surgery has spread all over the world. Not only single-scar but also no-scar operation is a current topic. In 2004, Kalloo reported the flexible transgastric peritoneoscopy as a novel approach to therapeutic interventions. In 2007, Marescaux reported transvaginal cholecystectomy in a patient. The breakthrough in robotic surgery was the development of the da Vinci Surgical System. It was introduced to Keio University Hospital in March 2000. Precision in the surgery will reach a higher level with the use of robotics. In collaboration with the faculty of technology and science, Keio University, the combined master-slave manipulator has been developed. The haptic forceps, which measure the elasticity of organs, have also been developed. The first possible sites of lymphatic metastasis are known as sentinel nodes. Otani reported vagus-sparing segmental gastrectomy under sentinel node navigation. This kind of function-preserving surgery will be performed frequently if the results of the multicenter prospective trial of the dual tracer method are favorable. Indocyanine green fluorescence-guided method using the HyperEye charge-coupled device camera system can be a highly sensitive method without using the radioactive colloid. 'Minimally invasive, function-preserving and precise surgery under sentinel node navigation in community hospital' may be a goal for us.

  11. Functional Analysis and Intervention for Breath Holding.

    Science.gov (United States)

    Kern, Lee; And Others

    1995-01-01

    A functional analysis of breath-holding episodes in a 7-year-old girl with severe mental retardation and Cornelia-de-Lange syndrome indicated that breath holding served an operant function, primarily to gain access to attention. Use of extinction, scheduled attention, and a picture card communication system decreased breath holding. (Author/SW)

  12. Affect and achievement goals in physical activity: a meta-analysis.

    Science.gov (United States)

    Ntoumanis, N; Biddle, S J

    1999-12-01

    Achievement goal orientation theory has been the subject of extensive research in recent years. In view of the importance of identifying the motivational antecedents of affect in physical activity, this study examined through meta-analysis the conflicting evidence regarding the links between different achievement goals and emotions. Using the formulas of Hunter and Schmidt (1), correlations were gathered from 41 independent samples and were corrected for both sampling and measurement errors. The results showed that task orientation and positive affect were moderately-to-highly correlated and in a positive fashion, whereas the relationship between task orientation and negative affect was negative and moderate to small. Both correlations were found to be heterogeneous, and so moderators were sought. The relationships between ego orientation and positive and negative affect were positive but very small, with the former being heterogeneous. Moderators coded were the time frame of affect (independent of context vs. after an athletic event), the physical activity setting (school physical education vs. recreation vs. competitive sport), age (university vs. school students), nationality (British vs. American), nature of negative affect (high vs. low arousal), and the publication status of the studies (published vs. unpublished). Lastly, a subset of the corrected correlations were inserted into a structural equation modelling analysis in order to look concurrently at the relationships among all the variables.

  13. Functional Analysis and Treatment of Aberrant Behavior.

    Science.gov (United States)

    Mace, F. Charles; And Others

    1991-01-01

    This article reviews general classes of variables which help to maintain aberrant behavior including attention seeking, sensory and perceptual consequences, and access to materials or activities. Suggestions for a methodology providing a comprehensive functional analysis are offered which include descriptive analysis, hypothesis forming,…

  14. Estimating Premorbid Functioning in Huntington's Disease: The Relationship between Disease Progression and the Wide Range Achievement Test Reading Subtest

    Science.gov (United States)

    O'Rourke, Justin J.F.; Adams, William H.; Duff, Kevin; Byars, Joanne; Nopoulos, Peg; Paulsen, Jane S.; Beglinger, Leigh J.

    2011-01-01

    The estimation of premorbid abilities is an essential part of a neuropsychological evaluation, especially in neurodegenerative conditions. Although word pronunciation tests are one standard method for estimating the premorbid level, research suggests that these tests may not be valid in neurodegenerative diseases. Therefore, the current study sought to examine two estimates of premorbid intellect, the Wide Range Achievement Test (WRAT) Reading subtest and the Barona formula, in 93 patients with mild to moderate Huntington's disease (HD) to determine their utility and to investigate how these measures relate to signs and symptoms of disease progression. In 89% of participants, WRAT estimates were below the Barona estimates. WRAT estimates were related to worsening memory and motor functioning, whereas the Barona estimates had weaker relationships. Neither estimate was related to depression or functional capacity. Irregular word reading tests appear to decline with HD progression, whereas estimation methods based on demographic factors may be more robust but overestimate premorbid functioning. PMID:21147861

  15. CHALLENGES REGARDING THE ELITE ISSUES IN ROMANIA DURING THE PERIOD OF ACHIEVING THE FUNDAMENTALS OF A FUNCTIONAL MARKET ECONOMY

    Directory of Open Access Journals (Sweden)

    Ioan DONE

    2005-06-01

    Full Text Available The functional market economy, characterised firstly by competitiveness cannot be achieved but with the immediate involvement of elite within all structures and all levels. This appreciation is largely confirmed by the economic-social successes of several states, called more and more meritocracy states.The road from chances to realities is strewn in all cases with difficulties and lacks, and each time the success is for individuals who are simultaneously aware and motivated. Romania has a high potential of elite’s generation, the share of over-endowed of total population being double in comparison to the world average. For our country a development strategy built on promoting elite and ensuring the conditions for reforms and professional achievement is necessary.

  16. Spectral theory and nonlinear functional analysis

    CERN Document Server

    Lopez-Gomez, Julian

    2001-01-01

    This Research Note addresses several pivotal problems in spectral theory and nonlinear functional analysis in connection with the analysis of the structure of the set of zeroes of a general class of nonlinear operators. It features the construction of an optimal algebraic/analytic invariant for calculating the Leray-Schauder degree, new methods for solving nonlinear equations in Banach spaces, and general properties of components of solutions sets presented with minimal use of topological tools. The author also gives several applications of the abstract theory to reaction diffusion equations and systems.The results presented cover a thirty-year period and include recent, unpublished findings of the author and his coworkers. Appealing to a broad audience, Spectral Theory and Nonlinear Functional Analysis contains many important contributions to linear algebra, linear and nonlinear functional analysis, and topology and opens the door for further advances.

  17. Functional Data Analysis Applied in Chemometrics

    DEFF Research Database (Denmark)

    Muller, Martha

    the worlds of statistics and chemometrics. We want to provide a glimpse of the essential and complex data pre-processing that is well known to chemometricians, but is generally unknown to statisticians. Pre-processing can potentially have a strong in uence on the results of consequent data analysis. Our......In this thesis we explore the use of functional data analysis as a method to analyse chemometric data, more specically spectral data in metabolomics. Functional data analysis is a vibrant eld in statistics. It has been rapidly expanding in both methodology and applications since it was made well...... known by Ramsay & Silverman's monograph in 1997. In functional data analysis, the data are curves instead of data points. Each curve is measured at discrete points along a continuum, for example, time or frequency. It is assumed that the underlying process generating the curves is smooth...

  18. Achieving the 30% Goal: Energy and Cost Savings Analysis of ASHRAE Standard 90.1-2010

    Energy Technology Data Exchange (ETDEWEB)

    Thornton, Brian A.; Rosenberg, Michael I.; Richman, Eric E.; Wang, Weimin; Xie, YuLong; Zhang, Jian; Cho, Heejin; Mendon, Vrushali V.; Athalye, Rahul A.; Liu, Bing

    2011-05-24

    This Technical Support Document presents the energy and cost savings analysis that PNNL conducted to measure the potential energy savings of 90.1-2010 relative to 90.1-2004. PNNL conducted this analysis with inputs from many other contributors and source of information. In particular, guidance and direction was provided by the Simulation Working Group under the auspices of the SSPC90.1. This report documents the approach and methodologies that PNNL developed to evaluate the energy saving achieved from use of ASHRAE/IES Standard 90.1-2010. Specifically, this report provides PNNL’s Progress Indicator process and methodology, EnergyPlus simulation framework, prototype model descriptions. This report covers the combined upgrades from 90.1-2004 to 90.1-2010, resulting in a total of 153 addenda. PNNL has reviewed and considered all 153 addenda for quantitative analysis in the Progress Indicator process. 53 of those are included in the quantitative analysis. This report provides information on the categorization of all of the addenda, a summary of the content, and deeper explanation of the impact and modeling of 53 identified addenda with quantitative savings.

  19. Is psychological membership in the classroom a function of standing out while fitting in? Implications for achievement motivation and emotions.

    Science.gov (United States)

    Gray, DeLeon L

    2017-04-01

    Education researchers have consistently linked students' perceptions of "fitting in" at school with patterns of motivation and positive emotions. This study proposes that "standing out" is also helpful for producing these outcomes, and that standing out works in concert with perceptions of fitting in. In a sample of 702 high school students nested within 33 classrooms, principal components analysis and confirmatory factor analysis were each conducted on half of the sample. Results support the proposed structure of measures of standing out and fitting in. Multilevel latent profile analysis was then used to classify students into four profiles of standing out while fitting in (SOFI): Unfulfilled, Somewhat Fulfilled, Nearly Fulfilled, and Fulfilled. A multinomial logistic regression revealed that students of color and those on who paid free/reduced prices lunch were overrepresented in the Unfulfilled and Somewhat Fulfilled profiles. A multilevel path analysis was then performed to assess the direct and indirect associations of profile membership with measures of task value and achievement emotions. Relative to the other profiles, students in the Fulfilled SOFI Profile express greater psychological membership in their classrooms and, in turn, express higher valuing of academic material (i.e., intrinsic value, utility value, and attainment value) and more positive achievement emotions (i.e., more enjoyment and pride; less boredom, hopelessness, and shame). This investigation provides critical insights on the potential benefits of structuring academic learning environments to foster feelings of distinctiveness among adolescents; and has implications for cultivating identities and achievement motivation in academic settings. Copyright © 2017 Society for the Study of School Psychology. Published by Elsevier Ltd. All rights reserved.

  20. Functional analysis in MR urography - made simple.

    Science.gov (United States)

    Khrichenko, Dmitry; Darge, Kassa

    2010-02-01

    MR urography (MRU) has proved to be a most advantageous imaging modality of the urinary tract in children, providing one-stop comprehensive morphological and functional information, without the utilization of ionizing radiation. The functional analysis of the MRU scan still requires external post-processing using relatively complex software. This has proved to be a limiting factor in widespread routine implementation of MRU functional analysis and use of MRU functional parameters similar to nuclear medicine. We present software, developed in a pediatric radiology department, that not only enables comprehensive automated functional analysis, but is also very user-friendly, fast, easily operated by the average radiologist or MR technician and freely downloadable at www.chop-fmru.com . A copy of IDL Virtual Machine is required for the installation, which is obtained at no charge at www.ittvis.com . The analysis software, known as "CHOP-fMRU," has the potential to help overcome the obstacles to widespread use of functional MRU in children.

  1. SURFACE TEXTURE ANALYSIS FOR FUNCTIONALITY CONTROL

    DEFF Research Database (Denmark)

    De Chiffre, Leonardo; Andreasen, Jan Lasson; Tosello, Guido

    This document is used in connection with three exercises of 3 hours duration as a part of the course VISION ONLINE – One week course on Precision & Nanometrology. The exercises concern surface texture analysis for functionality control, in connection with three different case stories. This docume...... contains a short description of each case story, 3-D roughness parameters analysis and relation with the product’s functionality.......This document is used in connection with three exercises of 3 hours duration as a part of the course VISION ONLINE – One week course on Precision & Nanometrology. The exercises concern surface texture analysis for functionality control, in connection with three different case stories. This document...

  2. The ups and downs of coping and sport achievement: an episodic process analysis of within-person associations.

    Science.gov (United States)

    Gaudreau, Patrick; Nicholls, Adam; Levy, Andrew R

    2010-06-01

    This study examined the relationship between coping and sport achievement at the within-person level of analysis. Fifty-four golfers completed diary measures of coping, stress, and sport achievement after six consecutive rounds of golf. Results of hierarchical linear modeling revealed golfers' episodic task-oriented coping and disengagement-oriented coping were associated, respectively, with their better and worst levels of subjective and objective achievement. Distraction-oriented coping was not significantly associated with achievement. These results were obtained after accounting for between-subjects differences in ability level and for within-person variations in perceived stress across both practice and competitive golf rounds. These results contribute to an emerging literature on the relationship between coping and sport achievement, and highlight the promises of an episodic process model of sport achievement to understand the transient self-regulatory factors associated with within-person variations in athletic achievement.

  3. Functional analysis of plastid-encoded genes

    OpenAIRE

    Swiatek, Magdalena

    2002-01-01

    Plastid chromosomes from the variety of plant species contain several conserved open reading frames of unknown function, which most probably represent functional genes. The primary aim of this thesis was the analysis of the role of two such ORFs, designated ycfs or hypothetical chloroplast reading frames, namely ycf9 (ORF62) and ycf10 (ORF229, cemA). Both were analyzed in Nicotiana tabacum (tobacco) via their inactivation using biolistic plastid transformation. A new experiment...

  4. Associations of Parenting Styles and Dimensions with Academic Achievement in Children and Adolescents: A Meta-Analysis

    Science.gov (United States)

    Pinquart, Martin

    2016-01-01

    Parents and researchers alike are interested in how to promote children's academic competence. The present meta-analysis integrates the results of 308 empirical studies on associations of general parenting dimensions and styles with academic achievement of children and adolescents assessed via grade point average or academic achievement tests.…

  5. Associations of Parenting Styles and Dimensions with Academic Achievement in Children and Adolescents: A Meta-Analysis

    Science.gov (United States)

    Pinquart, Martin

    2016-01-01

    Parents and researchers alike are interested in how to promote children's academic competence. The present meta-analysis integrates the results of 308 empirical studies on associations of general parenting dimensions and styles with academic achievement of children and adolescents assessed via grade point average or academic achievement tests.…

  6. A Multi-Level Simultaneous Analysis of How Student and School Characteristics Are Related to Students' English Language Achievement

    Science.gov (United States)

    Güvendir, Emre

    2015-01-01

    This study examines how student and school characteristics are related to Turkish students' English language achievement in Evaluation of Student Achievement Test (ÖBBS) of 2009. The participants of the study involve 43707 ninth year students who were required to take ÖBBS in 2009. For data analysis two level hierarchical linear modeling was…

  7. Choosing among Multiple Achievement Measures: Applying Multitrait--Multimethod Confirmatory Factor Analysis to State Assessment, ACT, and Student GPA Data

    Science.gov (United States)

    Dickinson, Emily R.; Adelson, Jill L.

    2016-01-01

    Practitioners and researchers interested in understanding student achievement, its predictors, and how it relates to other student outcomes are likely unaware of how the source information about achievement may offer subtly different pictures. This study applies multitrait-multimethod (MTMM) confirmatory factor analysis (CFA) within a structural…

  8. Choosing among Multiple Achievement Measures: Applying Multitrait--Multimethod Confirmatory Factor Analysis to State Assessment, ACT, and Student GPA Data

    Science.gov (United States)

    Dickinson, Emily R.; Adelson, Jill L.

    2016-01-01

    Practitioners and researchers interested in understanding student achievement, its predictors, and how it relates to other student outcomes are likely unaware of how the source information about achievement may offer subtly different pictures. This study applies multitrait-multimethod (MTMM) confirmatory factor analysis (CFA) within a structural…

  9. An Examination of Tri-Level Collaboration around Student Achievement Using the Gap Analysis Approach: Teacher Factors

    Science.gov (United States)

    Carruthers, Anthony Steven

    2013-01-01

    Using the Gap Analysis problem-solving framework (Clark & Estes, 2008), this project examined collaboration around student achievement in the Pasadena Unified School District (PUSD) from the teacher perspective. As part of a tri-level study, two other projects examined collaboration around student achievement in PUSD from the perspectives of…

  10. Electrochemical flow injection analysis of hydrazine in an excess of an active pharmaceutical ingredient: achieving pharmaceutical detection limits electrochemically.

    Science.gov (United States)

    Channon, Robert B; Joseph, Maxim B; Bitziou, Eleni; Bristow, Anthony W T; Ray, Andrew D; Macpherson, Julie V

    2015-10-06

    The quantification of genotoxic impurities (GIs) such as hydrazine (HZ) is of critical importance in the pharmaceutical industry in order to uphold drug safety. HZ is a particularly intractable GI and its detection represents a significant technical challenge. Here, we present, for the first time, the use of electrochemical analysis to achieve the required detection limits by the pharmaceutical industry for the detection of HZ in the presence of a large excess of a common active pharmaceutical ingredient (API), acetaminophen (ACM) which itself is redox active, typical of many APIs. A flow injection analysis approach with electrochemical detection (FIA-EC) is utilized, in conjunction with a coplanar boron doped diamond (BDD) microband electrode, insulated in an insulating diamond platform for durability and integrated into a two piece flow cell. In order to separate the electrochemical signature for HZ such that it is not obscured by that of the ACM (present in excess), the BDD electrode is functionalized with Pt nanoparticles (NPs) to significantly shift the half wave potential for HZ oxidation to less positive potentials. Microstereolithography was used to fabricate flow cells with defined hydrodynamics which minimize dispersion of the analyte and optimize detection sensitivity. Importantly, the Pt NPs were shown to be stable under flow, and a limit of detection of 64.5 nM or 0.274 ppm for HZ with respect to the ACM, present in excess, was achieved. This represents the first electrochemical approach which surpasses the required detection limits set by the pharmaceutical industry for HZ detection in the presence of an API and paves the wave for online analysis and application to other GI and API systems.

  11. Boolean nested canalizing functions: a comprehensive analysis

    CERN Document Server

    Li, Yuan; Murrugarra, David; Aguilar, Boris; Laubenbacher, Reinhard

    2012-01-01

    Boolean network models of molecular regulatory networks have been used successfully in computational systems biology. The Boolean functions that appear in published models tend to have special properties, in particular the property of being nested canalizing, a property inspired by the concept of canalization in evolutionary biology. It has been shown that networks comprised of nested canalizing functions have dynamic properties that make them suitable for modeling molecular regulatory networks, namely a small number of (large) attractors, as well as relatively short limit cycles. This paper contains a detailed analysis of this class of functions, based on a novel normal form as polynomial functions over the Boolean field. The concept of layer is introduced that stratifies variables into different classes depending on their level of dominance. Using this layer concept a closed form formula is derived for the number of nested canalizing functions with a given number of variables. Additional metrics analyzed in...

  12. The Effect of Web-Based Instruction on Achievement: A Meta- Analysis Study

    Directory of Open Access Journals (Sweden)

    Mucahit Camnalbur

    2013-08-01

    Full Text Available In this study, the master’s and PhD theses that compare web supported and web based teaching methods with traditional teaching methods according to their effect on students’ academic accomplishment and which are published in The Council of Higher Education (YOK National Theses Center’s database and that have been given permission to access have been examined. For this aim, 170 theses have been examined and 27 experimental studies that suit the meta-analysis inclusion criteria have been taken within the scope of the research. While including the studies in the research, a categorization as to at which level of the lesson (presentation, lesson preparation, exercise etc. the web supported teaching were used has not been made. In this study where meta-analytic effect analysis method has been used, the data have been analyzed and the effect size of web supported and web based applications on students’ academic success in the courses and topics that are dealt has been found as 0.807 compared to traditional method. According to this, a conclusion can be drawn that web supported instruction environments make a positive contribution on students’ academic achievement compared to the environments in which traditional teaching is carried out.

  13. The Effects of Mathematical Modelling on Students’ Achievement-Meta-Analysis of Research

    Directory of Open Access Journals (Sweden)

    Andrzej Sokolowski

    2015-01-01

    Full Text Available Using meta-analytic techniques this study examined the effects of applying mathematical modelling to support student math knowledge acquisition at the high school and college levels. The research encompassed experimental studies published in peer-reviewed journals between January 1, 2000, and February 27, 2013. Such formulated orientation called for extracting individual effect sizes of student achievement from the accumulated research conducting a moderator analysis. A systematic review of literature resulted in locating13 primary research articles involving 1,670 participants. The overall mean effect size; ES = 0.69 (SE = 0.05, 95% CI: 0.59–0.79 of a medium magnitude and positive direction supported the claim that mathematical modelling helps students understand and apply math concepts. A subsequent moderator analysis revealed differences of the effect sizes due to different modelling designs, aim of the modelling process, grade levels, and content domains. The research findings along with the discussion can be of interest to mathematics curriculum designers and practitioners who use modelling in their teaching practice.

  14. Constraint Analysis and Countermeasures for China s Forestry Scientific and Technological Achievements Transformation

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    This paper analyzes the constraint factors of forestry scientific and technological achievements transformation and explores the countermeasures and measures to promote the transformation. It points out that to achieve maximum return from investment funds in forestry research, it shall improve the transformation of scientific and technological achievements, enhance independent innovation capability, and greatly enhance the supply capacity of scientific and technological achievements, so as to provide endles...

  15. GPU accelerated dynamic functional connectivity analysis for functional MRI data.

    Science.gov (United States)

    Akgün, Devrim; Sakoğlu, Ünal; Esquivel, Johnny; Adinoff, Bryon; Mete, Mutlu

    2015-07-01

    Recent advances in multi-core processors and graphics card based computational technologies have paved the way for an improved and dynamic utilization of parallel computing techniques. Numerous applications have been implemented for the acceleration of computationally-intensive problems in various computational science fields including bioinformatics, in which big data problems are prevalent. In neuroimaging, dynamic functional connectivity (DFC) analysis is a computationally demanding method used to investigate dynamic functional interactions among different brain regions or networks identified with functional magnetic resonance imaging (fMRI) data. In this study, we implemented and analyzed a parallel DFC algorithm based on thread-based and block-based approaches. The thread-based approach was designed to parallelize DFC computations and was implemented in both Open Multi-Processing (OpenMP) and Compute Unified Device Architecture (CUDA) programming platforms. Another approach developed in this study to better utilize CUDA architecture is the block-based approach, where parallelization involves smaller parts of fMRI time-courses obtained by sliding-windows. Experimental results showed that the proposed parallel design solutions enabled by the GPUs significantly reduce the computation time for DFC analysis. Multicore implementation using OpenMP on 8-core processor provides up to 7.7× speed-up. GPU implementation using CUDA yielded substantial accelerations ranging from 18.5× to 157× speed-up once thread-based and block-based approaches were combined in the analysis. Proposed parallel programming solutions showed that multi-core processor and CUDA-supported GPU implementations accelerated the DFC analyses significantly. Developed algorithms make the DFC analyses more practical for multi-subject studies with more dynamic analyses.

  16. Implementation of production function of labor law as a means of achieving the social stability in Russia

    Directory of Open Access Journals (Sweden)

    Tatyana Aleksandrovna Izbiyenova

    2015-09-01

    Full Text Available Objective to determine the role and importance of the production function in the Russian labor law under modern conditions. Methods general comparative analysis abstraction analysis synthesis and speciallegal methods method of comparative law analysis technicallegal method etc.. Results the study proved the necessity of amendment in the civil law in terms of giving workers39 representatives the right to participate in the work of collective bodies of legal entities. The existing approaches to the formation of the management bodies do not allow to discuss the possibility of successful implementation of the production function of labour law. Scientific novelty for the first time by the examples of industrial democracy implementation in some foreign countries and in the Russian Federation the role and significance of industrial democracy was studied as the form of implementation of the production function of labour law. Practical significance the main provisions and conclusions of the article can be used in research activities when considering the functions of the Russian labour law and also in standardsetting activities for the improvement of normative legal acts. nbsp

  17. Biosensors in Health Care: The Milestones Achieved in Their Development towards Lab-on-Chip-Analysis

    Directory of Open Access Journals (Sweden)

    Suprava Patel

    2016-01-01

    Full Text Available Immense potentiality of biosensors in medical diagnostics has driven scientists in evolution of biosensor technologies and innovating newer tools in time. The cornerstone of the popularity of biosensors in sensing wide range of biomolecules in medical diagnostics is due to their simplicity in operation, higher sensitivity, ability to perform multiplex analysis, and capability to be integrated with different function by the same chip. There remains a huge challenge to meet the demands of performance and yield to its simplicity and affordability. Ultimate goal stands for providing point-of-care testing facility to the remote areas worldwide, particularly the developing countries. It entails continuous development in technology towards multiplexing ability, fabrication, and miniaturization of biosensor devices so that they can provide lab-on-chip-analysis systems to the community.

  18. Biosensors in Health Care: The Milestones Achieved in Their Development towards Lab-on-Chip-Analysis

    Science.gov (United States)

    Patel, Suprava; Nanda, Rachita; Sahoo, Sibasish; Mohapatra, Eli

    2016-01-01

    Immense potentiality of biosensors in medical diagnostics has driven scientists in evolution of biosensor technologies and innovating newer tools in time. The cornerstone of the popularity of biosensors in sensing wide range of biomolecules in medical diagnostics is due to their simplicity in operation, higher sensitivity, ability to perform multiplex analysis, and capability to be integrated with different function by the same chip. There remains a huge challenge to meet the demands of performance and yield to its simplicity and affordability. Ultimate goal stands for providing point-of-care testing facility to the remote areas worldwide, particularly the developing countries. It entails continuous development in technology towards multiplexing ability, fabrication, and miniaturization of biosensor devices so that they can provide lab-on-chip-analysis systems to the community. PMID:27042353

  19. A Complexity Analysis of Functional Interpretations

    DEFF Research Database (Denmark)

    Hernest, Mircea-Dan; Kohlenbach, Ulrich

    2003-01-01

    We give a quantitative analysis of G ̈odel’s functional interpretation and its monotone variant. The two have been used for the extraction of programs and numerical bounds as well as for conservation results. They apply both to (semi-)intuitionistic as well as (combined with negative translation)...

  20. A complexity analysis of functional interpretations

    DEFF Research Database (Denmark)

    Hernest, Mircea-Dan; Kohlenbach, Ulrich

    2005-01-01

    Summary: We give a quantitative analysis of Gödel's functional     interpretation and its monotone variant. The two have been used     for the extraction of programs and numerical bounds as well as     for conservation results. They apply both to (semi-)intuitionistic     as well as (combined...

  1. Pineal function : Impact of microarray analysis

    NARCIS (Netherlands)

    Klein, David C.; Bailey, Michael J.; Carter, David A.; Kim, Jong-so; Shi, Qiong; Ho, Anthony K.; Chik, Constance L.; Gaildrat, Pascaline; Morin, Fabrice; Ganguly, Surajit; Rath, Martin F.; Moller, Morten; Sugden, David; Rangel, Zoila G.; Munson, Peter J.; Weller, Joan L.; Coon, Steven L.

    2010-01-01

    Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retin

  2. Functional Analysis and Treatment of Severe Pica.

    Science.gov (United States)

    Mace, F. Charles; Knight, David

    1986-01-01

    A two-phase functional analysis of a profoundly retarded 19-year-old male's pica behavior resulted in an effective staff-implemented treatment consisting of limited staff-client interaction and removal of a protective helmet which had previously been prescribed to help control pica. (Author/JW)

  3. Functional data analysis of sleeping energy expenditure

    Science.gov (United States)

    Adequate sleep is crucial during childhood for metabolic health, and physical and cognitive development. Inadequate sleep can disrupt metabolic homeostasis and alter sleeping energy expenditure (SEE). Functional data analysis methods were applied to SEE data to elucidate the population structure of ...

  4. STATE-OF-THE-ART TASKS AND ACHIEVEMENTS OF PARALINGUISTIC SPEECH ANALYSIS SYSTEMS

    Directory of Open Access Journals (Sweden)

    A. A. Karpov

    2016-07-01

    Full Text Available We present analytical survey of state-of-the-art actual tasks in the area of computational paralinguistics, as well as the recent achievements of automatic systems for paralinguistic analysis of conversational speech. Paralinguistics studies non-verbal aspects of human communication and speech such as: natural emotions, accents, psycho-physiological states, pronunciation features, speaker’s voice parameters, etc. We describe architecture of a baseline computer system for acoustical paralinguistic analysis, its main components and useful speech processing methods. We present some information on an International contest called Computational Paralinguistics Challenge (ComParE, which is held each year since 2009 in the framework of the International conference INTERSPEECH organized by the International Speech Communication Association. We present sub-challenges (tasks that were proposed at the ComParE Challenges in 2009-2016, and analyze winning computer systems for each sub-challenge and obtained results. The last completed ComParE-2015 Challenge was organized in September 2015 in Germany and proposed 3 sub-challenges: 1 Degree of Nativeness (DN sub-challenge, determination of nativeness degree of speakers based on acoustics; 2 Parkinson's Condition (PC sub-challenge, recognition of a degree of Parkinson’s condition based on speech analysis; 3 Eating Condition (EC sub-challenge, determination of the eating condition state during speaking or a dialogue, and classification of consumed food type (one of seven classes of food by the speaker. In the last sub-challenge (EC, the winner was a joint Turkish-Russian team consisting of the authors of the given paper. We have developed the most efficient computer-based system for detection and classification of the corresponding (EC acoustical paralinguistic events. The paper deals with the architecture of this system, its main modules and methods, as well as the description of used training and evaluation

  5. Improving information retrieval in functional analysis.

    Science.gov (United States)

    Rodriguez, Juan C; González, Germán A; Fresno, Cristóbal; Llera, Andrea S; Fernández, Elmer A

    2016-12-01

    Transcriptome analysis is essential to understand the mechanisms regulating key biological processes and functions. The first step usually consists of identifying candidate genes; to find out which pathways are affected by those genes, however, functional analysis (FA) is mandatory. The most frequently used strategies for this purpose are Gene Set and Singular Enrichment Analysis (GSEA and SEA) over Gene Ontology. Several statistical methods have been developed and compared in terms of computational efficiency and/or statistical appropriateness. However, whether their results are similar or complementary, the sensitivity to parameter settings, or possible bias in the analyzed terms has not been addressed so far. Here, two GSEA and four SEA methods and their parameter combinations were evaluated in six datasets by comparing two breast cancer subtypes with well-known differences in genetic background and patient outcomes. We show that GSEA and SEA lead to different results depending on the chosen statistic, model and/or parameters. Both approaches provide complementary results from a biological perspective. Hence, an Integrative Functional Analysis (IFA) tool is proposed to improve information retrieval in FA. It provides a common gene expression analytic framework that grants a comprehensive and coherent analysis. Only a minimal user parameter setting is required, since the best SEA/GSEA alternatives are integrated. IFA utility was demonstrated by evaluating four prostate cancer and the TCGA breast cancer microarray datasets, which showed its biological generalization capabilities.

  6. Dynamic Blowout Risk Analysis Using Loss Functions.

    Science.gov (United States)

    Abimbola, Majeed; Khan, Faisal

    2017-08-11

    Most risk analysis approaches are static; failing to capture evolving conditions. Blowout, the most feared accident during a drilling operation, is a complex and dynamic event. The traditional risk analysis methods are useful in the early design stage of drilling operation while falling short during evolving operational decision making. A new dynamic risk analysis approach is presented to capture evolving situations through dynamic probability and consequence models. The dynamic consequence models, the focus of this study, are developed in terms of loss functions. These models are subsequently integrated with the probability to estimate operational risk, providing a real-time risk analysis. The real-time evolving situation is considered dependent on the changing bottom-hole pressure as drilling progresses. The application of the methodology and models are demonstrated with a case study of an offshore drilling operation evolving to a blowout. © 2017 Society for Risk Analysis.

  7. Effect of gender and nutritional status on academic achievement and cognitive function among primary school children in a rural district in Malaysia.

    Science.gov (United States)

    Hamid, Jan J M; Amal, Mitra K; Hasmiza, H; Pim, C D; Ng, L O; Wan, Manan W M

    2011-08-01

    The aim of this study was to investigate the relationship between gender, birth weight, nutritional status, and iron status of children with their academic performance and cognitive function. Two hundred and forty-nine children, seven to nine years of age, were recruited by systematic sampling from six primary schools in a rural area in Malaysia. Cognitive function was assessed by using Raven's Coloured Progressive Matrices (R-CPM). Academic performance of the children was recorded from their school final examination results in four subjects including Malay language, English, Mathematics, and Science. Birth weight was recorded from the birth certificate, and nutritional status was determined by weight-for-age z score and height-for-age z score. Girls had a significantly higher score in all the academic tests, but a lower cognitive score compared to boys. Nutritional status was found to be correlated significantly with academic performance. Academic and cognitive function scores were also found to be correlated significantly with birth weight, parents' education, and family income. In a multivariate analysis, gender remained the significant predictor of academic function, and iron status and haemoglobin were the significant predictors of cognitive function, after controlling for other variables. The study showed that girls performed better academically than boys in rural Malaysia. Nutritional status, parents' education and family income could be additional modifiable factors to improve academic performance of the children. More attention is needed to improve academic achievements of boys at their early school years.

  8. Investigating Linguistic Sources of Differential Item Functioning Using Expert Think-Aloud Protocols in Science Achievement Tests

    Science.gov (United States)

    Roth, Wolff-Michael; Oliveri, Maria Elena; Dallie Sandilands, Debra; Lyons-Thomas, Juliette; Ercikan, Kadriye

    2013-03-01

    Even if national and international assessments are designed to be comparable, subsequent psychometric analyses often reveal differential item functioning (DIF). Central to achieving comparability is to examine the presence of DIF, and if DIF is found, to investigate its sources to ensure differentially functioning items that do not lead to bias. In this study, sources of DIF were examined using think-aloud protocols. The think-aloud protocols of expert reviewers were conducted for comparing the English and French versions of 40 items previously identified as DIF (N = 20) and non-DIF (N = 20). Three highly trained and experienced experts in verifying and accepting/rejecting multi-lingual versions of curriculum and testing materials for government purposes participated in this study. Although there is a considerable amount of agreement in the identification of differentially functioning items, experts do not consistently identify and distinguish DIF and non-DIF items. Our analyses of the think-aloud protocols identified particular linguistic, general pedagogical, content-related, and cognitive factors related to sources of DIF. Implications are provided for the process of arriving at the identification of DIF, prior to the actual administration of tests at national and international levels.

  9. Functional Organosulfide Electrolyte Promotes an Alternate Reaction Pathway to Achieve High Performance in Lithium-Sulfur Batteries.

    Science.gov (United States)

    Chen, Shuru; Dai, Fang; Gordin, Mikhail L; Yu, Zhaoxin; Gao, Yue; Song, Jiangxuan; Wang, Donghai

    2016-03-18

    Lithium-sulfur (Li-S) batteries have recently received great attention because they promise to provide energy density far beyond current lithium ion batteries. Typically, Li-S batteries operate by conversion of sulfur to reversibly form different soluble lithium polysulfide intermediates and insoluble lithium sulfides through multistep redox reactions. Herein, we report a functional electrolyte system incorporating dimethyl disulfide as a co-solvent that enables a new electrochemical reduction pathway for sulfur cathodes. This pathway uses soluble dimethyl polysulfides and lithium organosulfides as intermediates and products, which can boost cell capacity and lead to improved discharge-charge reversibility and cycling performance of sulfur cathodes. This electrolyte system can potentially enable Li-S batteries to achieve high energy density.

  10. Reading Achievement in Relation to Phonological Coding and Awareness in Deaf Readers: A Meta-analysis

    Science.gov (United States)

    Mayberry, Rachel I.; del Giudice, Alex A.; Lieberman, Amy M.

    2011-01-01

    The relation between reading ability and phonological coding and awareness (PCA) skills in individuals who are severely and profoundly deaf was investigated with a meta-analysis. From an initial set of 230 relevant publications, 57 studies were analyzed that experimentally tested PCA skills in 2,078 deaf participants. Half of the studies found statistically significant evidence for PCA skills and half did not. A subset of 25 studies also tested reading proficiency and showed a wide range of effect sizes. Overall PCA skills predicted 11% of the variance in reading proficiency in the deaf participants. Other possible modulating factors, such as task type and reading grade level, did not explain the remaining variance. In 7 studies where it was measured, language ability predicted 35% of the variance in reading proficiency. These meta-analytic results indicate that PCA skills are a low to moderate predictor of reading achievement in deaf individuals and that other factors, most notably language ability, have a greater influence on reading development, as has been found to be the case in the hearing population. PMID:21071623

  11. Climate cure 2020 measures and instruments to achieve Norwegian climate goals by 2020. Chapter 10 - the transport sector analysis

    Energy Technology Data Exchange (ETDEWEB)

    2010-11-15

    This document is a translation of Chapter 10, Sector analysis of transport, in the Norwegian report Climate Cure 2020, Measures and Instruments for Achieving Norwegian Climate Goals by 2020. The sector analysis has been prepared by an inter agency working group, conducted by the Norwegian Public Road Administration. (Author)

  12. Biosensors for functional food safety and analysis.

    Science.gov (United States)

    Lavecchia, Teresa; Tibuzzi, Arianna; Giardi, Maria Teresa

    2010-01-01

    The importance of safety and functionality analysis of foodstuffs and raw materials is supported by national legislations and European Union (EU) directives concerning not only the amount of residues of pollutants and pathogens but also the activity and content of food additives and the health claims stated on their labels. In addition, consumers' awareness of the impact of functional foods' on their well-being and their desire for daily healthcare without the intake pharmaceuticals has immensely in recent years. Within this picture, the availability of fast, reliable, low cost control systems to measure the content and the quality of food additives and nutrients with health claims becomes mandatory, to be used by producers, consumers and the governmental bodies in charge of the legal supervision of such matters. This review aims at describing the most important methods and tools used for food analysis, starting with the classical methods (e.g., gas-chromatography GC, high performance liquid chromatography HPLC) and moving to the use of biosensors-novel biological material-based equipments. Four types of bio-sensors, among others, the novel photosynthetic proteins-based devices which are more promising and common in food analysis applications, are reviewed. A particular highlight on biosensors for the emerging market of functional foods is given and the most widely applied functional components are reviewed with a comprehensive analysis of papers published in the last three years; this report discusses recent trends for sensitive, fast, repeatable and cheap measurements, focused on the detection of vitamins, folate (folic acid), zinc (Zn), iron (Fe), calcium (Ca), fatty acids (in particular Omega 3), phytosterols and phytochemicals. A final market overview emphasizes some practical aspects ofbiosensor applications.

  13. Medial Cochlear Efferent Function: A Theoretical Analysis

    Science.gov (United States)

    Mountain, David C.

    2011-11-01

    Since the discovery of the cochlear efferent system, many hypotheses have been put forth for its function. These hypotheses for its function range from protecting the cochlea from over stimulation to improving the detection of sounds in noise. It is known that the medial efferent system innervates the outer hair cells and that stimulation of this system reduces basilar membrane and auditory nerve sensitivity which suggests that this system acts to decrease the gain of the cochlear amplifier. Here I present modeling results as well as analysis of published experimental data that suggest that the function of the medial efferent reflex is to decrease the cochlear amplifier gain by just the right amount so that the nonlinearity in the basilar membrane response lines up perfectly with the inner hair cell nonlinear transduction process to produce a hair cell receptor potential that is proportional to the logarithm of the sound pressure level.

  14. Industrial entrepreneurial network: Structural and functional analysis

    Science.gov (United States)

    Medvedeva, M. A.; Davletbaev, R. H.; Berg, D. B.; Nazarova, J. J.; Parusheva, S. S.

    2016-12-01

    Structure and functioning of two model industrial entrepreneurial networks are investigated in the present paper. One of these networks is forming when implementing an integrated project and consists of eight agents, which interact with each other and external environment. The other one is obtained from the municipal economy and is based on the set of the 12 real business entities. Analysis of the networks is carried out on the basis of the matrix of mutual payments aggregated over the certain time period. The matrix is created by the methods of experimental economics. Social Network Analysis (SNA) methods and instruments were used in the present research. The set of basic structural characteristics was investigated: set of quantitative parameters such as density, diameter, clustering coefficient, different kinds of centrality, and etc. They were compared with the random Bernoulli graphs of the corresponding size and density. Discovered variations of random and entrepreneurial networks structure are explained by the peculiarities of agents functioning in production network. Separately, were identified the closed exchange circuits (cyclically closed contours of graph) forming an autopoietic (self-replicating) network pattern. The purpose of the functional analysis was to identify the contribution of the autopoietic network pattern in its gross product. It was found that the magnitude of this contribution is more than 20%. Such value allows using of the complementary currency in order to stimulate economic activity of network agents.

  15. Longitudinal Analysis of Chinese High School Student's Stress in School and Academic Achievement

    Science.gov (United States)

    Liu, Yangyang; Lu, Zuhong

    2011-01-01

    In previous research, few studies have examined the effects of adolescents' stress in school on the change rates of their academic achievement. In the present study, we seek to examine the longitudinal relationships between adolescents' stress in school and the change rates of their academic achievement. The results indicated that for those whose…

  16. Behavioral Engagement in Learning and Math Achievement over Kindergarten: A Contextual Analysis

    Science.gov (United States)

    Robinson, Keith; Mueller, Anna S.

    2014-01-01

    Using nationally representative data on 12,462 kindergarten children, this report examines the link between behavioral engagement and math achievement growth during kindergarten. Multilevel models show that students with higher individual engagement tend to experience larger math achievement growth over kindergarten, that classroom engagement…

  17. Effectiveness of Computer-Assisted Mathematics Education (CAME) over Academic Achievement: A Meta-Analysis Study

    Science.gov (United States)

    Demir, Seda; Basol, Gülsah

    2014-01-01

    The aim of the current study is to determine the overall effects of Computer-Assisted Mathematics Education (CAME) on academic achievement. After an extensive review of the literature, studies using Turkish samples and observing the effects of Computer-Assisted Education (CAE) on mathematics achievement were examined. As a result of this…

  18. Analysis of Relationships among Burnout, Academic Achievement, and Self-Regulation

    Science.gov (United States)

    Duru, Erdinç; Duru, Sibel; Balkis, Murat

    2014-01-01

    This study examined the relationships among burnout, academic achievement, and self-regulation with two structural models. The participants were 383 undergraduates with different majors in a university in the western part of Turkey. The results showed that academic achievement was negatively associated with three dimensions of burnout and was…

  19. Understanding Mathematics Achievement: An Analysis of the Effects of Student and Family Factors

    Science.gov (United States)

    Goforth, Kate; Noltemeyer, Amity; Patton, Jon; Bush, Kevin R.; Bergen, Doris

    2014-01-01

    Educators are increasingly recognising the importance of improving students' mathematics achievement. Much of the current research focuses on the impact of instructional variables on mathematics achievement. The goal of this study was to examine the influence of less researched variables--family and student factors. Participants were 747…

  20. Influence of Socioeconomic Disadvantages on Mathematics Achievement: A Multilevel Cohort Analysis

    Science.gov (United States)

    Singh, Malkeet

    2015-01-01

    Closing the achievement gap in public education is a worthy goal that has been included as a top priority in the No Child Left Behind Act of 2001 (2002). This study analyzed the most salient predictors at the student and school levels to identify their long-term impact on mathematics achievement from the elementary grades to high school. The…

  1. Longitudinal Analysis of Chinese High School Student's Stress in School and Academic Achievement

    Science.gov (United States)

    Liu, Yangyang; Lu, Zuhong

    2011-01-01

    In previous research, few studies have examined the effects of adolescents' stress in school on the change rates of their academic achievement. In the present study, we seek to examine the longitudinal relationships between adolescents' stress in school and the change rates of their academic achievement. The results indicated that for those whose…

  2. A Comparative Analysis of Preschool Attendance and Reading Achievement among Second-Grade Students

    Science.gov (United States)

    Burton, Kelly Latham

    2011-01-01

    Preschool attendance is considered an important factor for predicting later success in literacy achievement. This quantitative ex-post facto study examined whether attendance of public prekindergarten is related to improved reading achievement in 2nd grade students in a rural, southeastern school district. The learning theories of Piaget, Bandura,…

  3. An Analysis of Java Programming Behaviors, Affect, Perceptions, and Syntax Errors among Low-Achieving, Average, and High-Achieving Novice Programmers

    Science.gov (United States)

    Rodrigo, Ma. Mercedes T.; Andallaza, Thor Collin S.; Castro, Francisco Enrique Vicente G.; Armenta, Marc Lester V.; Dy, Thomas T.; Jadud, Matthew C.

    2013-01-01

    In this article we quantitatively and qualitatively analyze a sample of novice programmer compilation log data, exploring whether (or how) low-achieving, average, and high-achieving students vary in their grasp of these introductory concepts. High-achieving students self-reported having the easiest time learning the introductory programming…

  4. An Analysis of Java Programming Behaviors, Affect, Perceptions, and Syntax Errors among Low-Achieving, Average, and High-Achieving Novice Programmers

    Science.gov (United States)

    Rodrigo, Ma. Mercedes T.; Andallaza, Thor Collin S.; Castro, Francisco Enrique Vicente G.; Armenta, Marc Lester V.; Dy, Thomas T.; Jadud, Matthew C.

    2013-01-01

    In this article we quantitatively and qualitatively analyze a sample of novice programmer compilation log data, exploring whether (or how) low-achieving, average, and high-achieving students vary in their grasp of these introductory concepts. High-achieving students self-reported having the easiest time learning the introductory programming…

  5. Shape Error Analysis of Functional Surface Based on Isogeometrical Approach

    Science.gov (United States)

    YUAN, Pei; LIU, Zhenyu; TAN, Jianrong

    2017-05-01

    The construction of traditional finite element geometry (i.e., the meshing procedure) is time consuming and creates geometric errors. The drawbacks can be overcame by the Isogeometric Analysis (IGA), which integrates the computer aided design and structural analysis in a unified way. A new IGA beam element is developed by integrating the displacement field of the element, which is approximated by the NURBS basis, with the internal work formula of Euler-Bernoulli beam theory with the small deformation and elastic assumptions. Two cases of the strong coupling of IGA elements, "beam to beam" and "beam to shell", are also discussed. The maximum relative errors of the deformation in the three directions of cantilever beam benchmark problem between analytical solutions and IGA solutions are less than 0.1%, which illustrate the good performance of the developed IGA beam element. In addition, the application of the developed IGA beam element in the Root Mean Square (RMS) error analysis of reflector antenna surface, which is a kind of typical functional surface whose precision is closely related to the product's performance, indicates that no matter how coarse the discretization is, the IGA method is able to achieve the accurate solution with less degrees of freedom than standard Finite Element Analysis (FEA). The proposed research provides an effective alternative to standard FEA for shape error analysis of functional surface.

  6. A Framework for Achieving Situational Awareness during Crisis based on Twitter Analysis

    Science.gov (United States)

    Zielinski, Andrea; Tokarchuk, Laurissa; Middleton, Stuart; Chaves, Fernando

    2013-04-01

    Decision Support Systems for Natural Crisis Management increasingly employ Web 2.0 and 3.0 technologies for future collaborative decision making, including the use of social networks like Twitter. However, human sensor data is not readily accessible and interpretable, since the texts are unstructured, noisy and available in various languages. The present work focusses on the detection of crisis events in a multilingual setting as part of the FP7-funded EU project TRIDEC and is motivated by the goal to establish a Tsunami warning system for the Mediterranean. It is integrated into a dynamic spatial-temporal decision making component with a command and control unit's graphical user interface that presents all relevant information to the human operator to support critical decision-support. To this end, a tool for the interactive visualization of geospatial data is implemented: All tweets with an exact timestamp or geo-location are monitored on the map in real-time so that the operator on duty can get an overall picture of the situation. Apart from the human sensor data, the seismic sensor data will appear also on the same screen. Signs of abnormal activity from twitter usage in social networks as well as in sensor networks devices can then be used to trigger official warning alerts according to the CAP message standard. Whenever a certain threshold of relevant tweets in a HASC region (Hierarchical Administrative Subdivision Code) is exceeded, the twitter activity in this administrative region will be shown on a map. We believe that the following functionalities are crucial for monitoring crisis, making use of text mining and network analysis techniques: Focussed crawling, trustworthyness analysis geo-parsing, and multilingual tweet classification. In the first step, the Twitter Streaming API accesses the social data, using an adaptive keyword list (focussed crawling). Then, tweets are filtered and aggregated to form counts for a certain time-span (e.g., an interval of

  7. Semen analysis and sperm function testing

    Institute of Scientific and Technical Information of China (English)

    Daniel R Franken; Sergio Oehninger

    2012-01-01

    Despite controversy regarding the clinical value of semen analysis,male fertility investigation still relies on a standardized analysis of the semen parameters.This is especially true for infertility clinics in both developing and developed countries.Other optional tests or sophisticated technologies have not been widely applied.The current review addresses important changes in the analysis of semen as described in the new World Health Organization (WHO) manual for semen analysis.The most important change in the manual is the use of evidence-based publications as references to determine cutoff values for normality.Apart from the above mentioned changes,the initial evaluation and handling methods remain,in most instances,the same as in previous editions.Furthermore,the review evaluates the importance of quality control in andrology with emphasis on the evaluation of sperm morphology.WHO sperm morphology training programmes for Sub-Saharan countries were initiated at Tygerberg Hospital in 1995.1he external quality control programme has ensured that the majority of participants have maintained their morphological reading skills acquired during initial training.This review reports on current sperm functional tests,such as the induced acrosome reaction,and sperm-zona pellucida binding assays,as well as the impact of sperm qualitv in terms of DNA integritv,and the relationship of sperm function tests to sperm morphologv.

  8. Integrating anatomy and function for zebrafish circuit analysis.

    Science.gov (United States)

    Arrenberg, Aristides B; Driever, Wolfgang

    2013-01-01

    Due to its transparency, virtually every brain structure of the larval zebrafish is accessible to light-based interrogation of circuit function. Advanced stimulation techniques allow the activation of optogenetic actuators at different resolution levels, and genetically encoded calcium indicators report the activity of a large proportion of neurons in the CNS. Large datasets result and need to be analyzed to identify cells that have specific properties-e.g., activity correlation to sensory stimulation or behavior. Advances in three-dimensional (3D) functional mapping in zebrafish are promising; however, the mere coordinates of implicated neurons are not sufficient. To comprehensively understand circuit function, these functional maps need to be placed into the proper context of morphological features and projection patterns, neurotransmitter phenotypes, and key anatomical landmarks. We discuss the prospect of merging functional and anatomical data in an integrated atlas from the perspective of our work on long-range dopaminergic neuromodulation and the oculomotor system. We propose that such a resource would help researchers to surpass current hurdles in circuit analysis to achieve an integrated understanding of anatomy and function.

  9. Achieving a Collapsible, Strong, and Highly Thermally Conductive Film Based on Oriented Functionalized Boron Nitride Nanosheets and Cellulose Nanofiber.

    Science.gov (United States)

    Wu, Kai; Fang, Jinchao; Ma, Jinrui; Huang, Rui; Chai, Songgang; Chen, Feng; Fu, Qiang

    2017-09-06

    Boron nitride nanosheet (BNNS) films receive wide attention in both academia and industry because of their high thermal conductivity (TC) and good electrical insulation capability. However, the brittleness and low strength of the BNNS film largely limit its application. Herein, functionalized BNNSs (f-BNNSs) with a well-maintained in-plane crystalline structure were first prepared utilizing urea in the aqueous solution via ball-milling for the purpose of improving their stability in water and enhancing the interaction with the polymer matrix. Then, a biodegradable and highly thermally conductive film with an orderly oriented structure based on cellulose nanofibers (CNFs) and f-BNNSs was prepared just by simple vacuum-assisted filtration. The modification of the BNNS and the introduction of the CNF result in a better orientation of the f-BNNS, sufficient connection between f-BNNS themselves, and strong interaction between f-BNNS and CNF, which not only make the prepared composite film strong and tough but also possess higher in-plane TC. An increase of 70% in-plane TC, 63.2% tensile strength, and 77.8% elongation could be achieved for CNF/f-BNNS films, compared with that for CNF/BNNS films at the filler content of 70%. Although at such a high f-BNNS content, this composite film can be bended and folded. It is even more interesting to find that the in-plane TC could be greatly enhanced with the decrease of the thickness of the film, and a value of 30.25 W/m K can be achieved at the thickness of ∼30 μm for the film containing 70 wt % f-BNNS. We believe that this highly thermally conductive film with good strength and toughness could have potential applications in next-generation highly powerful and collapsible electronic devices.

  10. Analysis of attitude and achievement using the 5E instructional model in an interactive television environment

    Science.gov (United States)

    Cherry, Gamaliel R.

    The purpose of this quasi-experimental study was to examine attitude and achievement among fifth grade students participating in inquiry and lecture-based forms of instruction through interactive television. Participants (N = 260) were drawn from registered users of NASA's Digital Learning Network(TM). The first three levels of Bloom's Revised Taxonomy were used to measure levels of achievement while the Science Attitude Inventory II was used to measure science attitudes. Results indicated a significant interaction between inquiry and topic area, as well as achievement for remember, understand, and apply levels of Bloom's Revised Taxonomy. Differences between mean scores were in favor of the treatment group on both topic and achievement levels. Findings echo research that encourages the use of inquiry-based instruction to improve achievement. This study also serves as a reference for supplemental content providers searching for an effective instructional strategy when delivering instruction through interactive television. Recommendations for future research include the examination of: development time between inquiry-based and lecture-based strategies, a longitudinal study of attitude and achievement from elementary through middle school, differences between interactive television sessions and asynchronous sessions, and types of inquiry-based instruction related to student achievement and retention through interactive television.

  11. Position Paper: Applying Machine Learning to Software Analysis to Achieve Trusted, Repeatable Scientific Computing

    Energy Technology Data Exchange (ETDEWEB)

    Prowell, Stacy J [ORNL; Symons, Christopher T [ORNL

    2015-01-01

    Producing trusted results from high-performance codes is essential for policy and has significant economic impact. We propose combining rigorous analytical methods with machine learning techniques to achieve the goal of repeatable, trustworthy scientific computing.

  12. Functional Analysis of Arabidopsis Sucrose Transporters

    Energy Technology Data Exchange (ETDEWEB)

    John M. Ward

    2009-03-31

    Sucrose is the main photosynthetic product that is transported in the vasculature of plants. The long-distance transport of carbohydrates is required to support the growth and development of net-importing (sink) tissues such as fruit, seeds and roots. This project is focused on understanding the transport mechanism sucrose transporters (SUTs). These are proton-coupled sucrose uptake transporters (membrane proteins) that are required for transport of sucrose in the vasculature and uptake into sink tissues. The accomplishments of this project included: 1) the first analysis of substrate specificity for any SUT. This was accomplished using electrophysiology to analyze AtSUC2, a sucrose transporter from companion cells in Arabidopsis. 2) the first analysis of the transport activity for a monocot SUT. The transport kinetics and substrate specificity of HvSUT1 from barley were studied. 3) the first analysis of a sucrose transporter from sugarcane. and 4) the first analysis of transport activity of a sugar alcohol transporter homolog from plants, AtPLT5. During this period four primary research papers, funded directly by the project, were published in refereed journals. The characterization of several sucrose transporters was essential for the current effort in the analysis of structure/function for this gene family. In particular, the demonstration of strong differences in substrate specificity between type I and II SUTs was important to identify targets for site-directed mutagenesis.

  13. Latent Structure Analysis of Longitudinal Data on Relations Between Intellectual Abilities and School Achievement.

    Science.gov (United States)

    Kuusinen, J; Leskinen, E

    1988-01-01

    Covariance structure modelling by LISREL was applied to analyze the relations between intellectual ability, as measured by ITPA, and achievement in reading, writing, foreign language and mathematics in longitudinal data with 8 to 10 years' time interval between measurements. The subjects' (N = 234) ability scores were obtained at 5-7 years of age, and their achievement was measured at 14-16 years of age. The effect of ability to achievement was studied by analyzing structural equation models on both first-order ability and achievement factors and by developing a two-stage second-order factor estimation method for structural equation parameters between first-order ability and achievement factors. Squared multiple correlations and coefficients of determination as indices of explained variance were derived for reduced forms of structural equations. The general latent intellectual ability explained 49% of variance in school achievement. The results showed the high validity of ITPA in explaining school success as well as the great flexibility and usefulness of covariance structure modelling by LISREL in analyzing longitudinal data.

  14. Can Research Design Explain Variation in Head Start Research Results? A Meta-Analysis of Cognitive and Achievement Outcomes

    Science.gov (United States)

    Shager, Hilary M.; Schindler, Holly S.; Magnuson, Katherine A.; Duncan, Greg J.; Yoshikawa, Hirokazu; Hart, Cassandra M. D.

    2013-01-01

    This study explores the extent to which differences in research design explain variation in Head Start program impacts. We employ meta-analytic techniques to predict effect sizes for cognitive and achievement outcomes as a function of the type and rigor of research design, quality and type of outcome measure, activity level of control group, and…

  15. Can Research Design Explain Variation in Head Start Research Results? A Meta-Analysis of Cognitive and Achievement Outcomes

    Science.gov (United States)

    Shager, Hilary M.; Schindler, Holly S.; Magnuson, Katherine A.; Duncan, Greg J.; Yoshikawa, Hirokazu; Hart, Cassandra M. D.

    2013-01-01

    This study explores the extent to which differences in research design explain variation in Head Start program impacts. We employ meta-analytic techniques to predict effect sizes for cognitive and achievement outcomes as a function of the type and rigor of research design, quality and type of outcome measure, activity level of control group, and…

  16. FANTOM: Functional and taxonomic analysis of metagenomes

    Directory of Open Access Journals (Sweden)

    Sanli Kemal

    2013-02-01

    Full Text Available Abstract Background Interpretation of quantitative metagenomics data is important for our understanding of ecosystem functioning and assessing differences between various environmental samples. There is a need for an easy to use tool to explore the often complex metagenomics data in taxonomic and functional context. Results Here we introduce FANTOM, a tool that allows for exploratory and comparative analysis of metagenomics abundance data integrated with metadata information and biological databases. Importantly, FANTOM can make use of any hierarchical database and it comes supplied with NCBI taxonomic hierarchies as well as KEGG Orthology, COG, PFAM and TIGRFAM databases. Conclusions The software is implemented in Python, is platform independent, and is available at http://www.sysbio.se/Fantom.

  17. Bioprospecting and Functional Analysis of Neglected Environments

    DEFF Research Database (Denmark)

    Vogt, Josef Korbinian

    of functional relationships in single organisms and environments. The sequencing data can also be mined for novel compounds and enzymes. The process of exploiting biological resources for commercial use is known as bioprospecting. This PhD thesis describes the concept of bioprospecting in the post genomic era...... on Biological Diversity (explained in Chapter 3). Proteolytic enzymes – described in Chapter 4 – are the target for bioprospecting due to their high market value. Section II describes methods used for the analysis of metagenomic and RNA-seq datasets, including Manuscript I, which includes the taxonomic...

  18. Functional analysis and the Feynman operator calculus

    CERN Document Server

    Gill, Tepper L

    2016-01-01

    This book provides the mathematical foundations for Feynman's operator calculus and for the Feynman path integral formulation of quantum mechanics as a natural extension of analysis and functional analysis to the infinite-dimensional setting. In one application, the results are used to prove the last two remaining conjectures of Freeman Dyson for quantum electrodynamics. In another application, the results are used to unify methods and weaken domain requirements for non-autonomous evolution equations. Other applications include a general theory of Lebesgue measure on Banach spaces with a Schauder basis and a new approach to the structure theory of operators on uniformly convex Banach spaces. This book is intended for advanced graduate students and researchers.

  19. Functional Analysis of Split Airport Business Processes

    Directory of Open Access Journals (Sweden)

    Slavko Roguljić

    2005-01-01

    Full Text Available Optimisation of business processes represents the basis ofimproving the competitiveness of the Ailport as a service pro·vider. This directly implies not only the analysis and creation ofthe model of current organisation and technological processesbut also the necessity to measure these processes in order to reorganiseand improve them. Consequently, the Split AitportAuthority considers the functional analysis of its business processesas one of the major issues. Since in April2002 the analysisand modelling were completed in all the organisational unitsof handling setvice and cargo department organisational structures,both of the organisational structure of these services, aswell as of processes of aircraft, passenger, baggage and cargohandling, this paper will analyse the implementation of ARISComputer System at Split Airport Ground Handling Process.

  20. A Complexity Analysis of Functional Interpretations

    DEFF Research Database (Denmark)

    Hernest, Mircea-Dan; Kohlenbach, Ulrich

    2003-01-01

    We give a quantitative analysis of G ̈odel’s functional interpretation and its monotone variant. The two have been used for the extraction of programs and numerical bounds as well as for conservation results. They apply both to (semi-)intuitionistic as well as (combined with negative translation......) classical proofs. The proofs may be formalized in systems ranging from weak base systems to arithmetic and analysis (and numerous fragments of these). We give upper bounds in basic proof data on the depth, size, maximal type degree and maximal type arity of the extracted terms as well as on the depth...... of the verifying proof. In all cases terms of size linear in the size of the proof at input can be extracted and the corresponding extraction algorithms have cubic worst-time complexity. The verifying proofs have depth linear in the depth of the proof at input and the maximal size of a formula of this proof....

  1. Functional analysis of the Aspergillus nidulans kinome.

    Science.gov (United States)

    De Souza, Colin P; Hashmi, Shahr B; Osmani, Aysha H; Andrews, Peter; Ringelberg, Carol S; Dunlap, Jay C; Osmani, Stephen A

    2013-01-01

    The filamentous fungi are an ecologically important group of organisms which also have important industrial applications but devastating effects as pathogens and agents of food spoilage. Protein kinases have been implicated in the regulation of virtually all biological processes but how they regulate filamentous fungal specific processes is not understood. The filamentous fungus Aspergillus nidulans has long been utilized as a powerful molecular genetic system and recent technical advances have made systematic approaches to study large gene sets possible. To enhance A. nidulans functional genomics we have created gene deletion constructs for 9851 genes representing 93.3% of the encoding genome. To illustrate the utility of these constructs, and advance the understanding of fungal kinases, we have systematically generated deletion strains for 128 A. nidulans kinases including expanded groups of 15 histidine kinases, 7 SRPK (serine-arginine protein kinases) kinases and an interesting group of 11 filamentous fungal specific kinases. We defined the terminal phenotype of 23 of the 25 essential kinases by heterokaryon rescue and identified phenotypes for 43 of the 103 non-essential kinases. Uncovered phenotypes ranged from almost no growth for a small number of essential kinases implicated in processes such as ribosomal biosynthesis, to conditional defects in response to cellular stresses. The data provide experimental evidence that previously uncharacterized kinases function in the septation initiation network, the cell wall integrity and the morphogenesis Orb6 kinase signaling pathways, as well as in pathways regulating vesicular trafficking, sexual development and secondary metabolism. Finally, we identify ChkC as a third effector kinase functioning in the cellular response to genotoxic stress. The identification of many previously unknown functions for kinases through the functional analysis of the A. nidulans kinome illustrates the utility of the A. nidulans gene

  2. Functional analysis of the Aspergillus nidulans kinome.

    Directory of Open Access Journals (Sweden)

    Colin P De Souza

    Full Text Available The filamentous fungi are an ecologically important group of organisms which also have important industrial applications but devastating effects as pathogens and agents of food spoilage. Protein kinases have been implicated in the regulation of virtually all biological processes but how they regulate filamentous fungal specific processes is not understood. The filamentous fungus Aspergillus nidulans has long been utilized as a powerful molecular genetic system and recent technical advances have made systematic approaches to study large gene sets possible. To enhance A. nidulans functional genomics we have created gene deletion constructs for 9851 genes representing 93.3% of the encoding genome. To illustrate the utility of these constructs, and advance the understanding of fungal kinases, we have systematically generated deletion strains for 128 A. nidulans kinases including expanded groups of 15 histidine kinases, 7 SRPK (serine-arginine protein kinases kinases and an interesting group of 11 filamentous fungal specific kinases. We defined the terminal phenotype of 23 of the 25 essential kinases by heterokaryon rescue and identified phenotypes for 43 of the 103 non-essential kinases. Uncovered phenotypes ranged from almost no growth for a small number of essential kinases implicated in processes such as ribosomal biosynthesis, to conditional defects in response to cellular stresses. The data provide experimental evidence that previously uncharacterized kinases function in the septation initiation network, the cell wall integrity and the morphogenesis Orb6 kinase signaling pathways, as well as in pathways regulating vesicular trafficking, sexual development and secondary metabolism. Finally, we identify ChkC as a third effector kinase functioning in the cellular response to genotoxic stress. The identification of many previously unknown functions for kinases through the functional analysis of the A. nidulans kinome illustrates the utility of the

  3. Single-parent households and children's educational achievement: A state-level analysis.

    Science.gov (United States)

    Amato, Paul R; Patterson, Sarah; Beattie, Brett

    2015-09-01

    Although many studies have examined associations between family structure and children's educational achievement at the individual level, few studies have considered how the increase in single-parent households may have affected children's educational achievement at the population level. We examined changes in the percentage of children living with single parents between 1990 and 2011 and state mathematics and reading scores on the National Assessment of Educational Progress. Regression models with state and year fixed effects revealed that changes in the percentage of children living with single parents were not associated with test scores. Increases in maternal education, however, were associated with improvements in children's test scores during this period. These results do not support the notion that increases in single parenthood have had serious consequences for U.S. children's school achievement.

  4. Biosignals Analysis for Kidney Function Effect Analysis of Fennel Aromatherapy

    Directory of Open Access Journals (Sweden)

    Bong-Hyun Kim

    2015-01-01

    Full Text Available Human effort in order to enjoy a healthy life is diverse. IT technology to these analyzes, the results of development efforts, it has been applied. Therefore, I use the care and maintenance diagnostic health management and prevention than treatment. In particular, the aromatherapy treatment easy to use without the side effects there is no irritation, are widely used in modern society. In this paper, we measured the aroma effect by applying a biosignal analysis techniques; an experiment was performed to analyze. In particular, we design methods and processes of research based on the theory aroma that affect renal function. Therefore, in this paper, measuring the biosignals and after fennel aromatherapy treatment prior to the enforcement of the mutual comparison, through the analysis, studies were carried out to analyze the effect of fennel aromatherapy therapy on kidney function.

  5. The moderating effect of self-efficacy on normal-weight, overweight, and obese children's math achievement: a longitudinal analysis.

    Science.gov (United States)

    Kranjac, Ashley Wendell

    2015-03-01

    Increased body weight is associated with decreased cognitive function in school-aged children. The role of self-efficacy in shaping the connection between children's educational achievement and obesity-related comorbidities has not been examined to date. Evidence of the predictive ability of self-efficacy in children is demonstrated in cognitive tasks, including math achievement scores. This study examined the relationship between self-efficacy and math achievement in normal weight, overweight, and obese children. I hypothesized that overweight and obese children with higher self-efficacy will be less affected in math achievement than otherwise comparable children with lower self-efficacy. I tested this prediction with multilevel growth modeling techniques using the ECLS-K 1998-1999 survey data, a nationally representative sample of children. Increased self-efficacy moderates the link between body weight and children's math achievement by buffering the risks that increased weight status poses to children's cognitive function. My findings indicate that self-efficacy moderates math outcomes in overweight, but not obese, children. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Structural and functional analysis of rice genome

    Indian Academy of Sciences (India)

    Akhilesh K. Tyagi; Jitendra P. Khurana; Paramjit Khurana; Saurabh Raghuvanshi; Anupama Gaur; Anita Kapur; Vikrant Gupta; Dibyendu Kumar; V. Ravi; Shubha Vij; Parul Khurana; Sulabha Sharma

    2004-04-01

    Rice is an excellent system for plant genomics as it represents a modest size genome of 430 Mb. It feeds more than half the population of the world. Draft sequences of the rice genome, derived by whole-genome shotgun approach at relatively low coverage (4–6 X), were published and the International Rice Genome Sequencing Project (IRGSP) declared high quality (>10 X), genetically anchored, phase 2 level sequence in 2002. In addition, phase 3 level finished sequence of chromosomes 1, 4 and 10 (out of 12 chromosomes of rice) has already been reported by scientists from IRGSP consortium. Various estimates of genes in rice place the number at > 50,000. Already, over 28,000 full-length cDNAs have been sequenced, most of which map to genetically anchored genome sequence. Such information is very useful in revealing novel features of macro- and micro-level synteny of rice genome with other cereals. Microarray analysis is unraveling the identity of rice genes expressing in temporal and spatial manner and should help target candidate genes useful for improving traits of agronomic importance. Simultaneously, functional analysis of rice genome has been initiated by marker-based characterization of useful genes and employing functional knock-outs created by mutation or gene tagging. Integration of this enormous information is expected to catalyze tremendous activity on basic and applied aspects of rice genomics.

  7. Problems in real and functional analysis

    CERN Document Server

    Torchinsky, Alberto

    2015-01-01

    It is generally believed that solving problems is the most important part of the learning process in mathematics because it forces students to truly understand the definitions, comb through the theorems and proofs, and think at length about the mathematics. The purpose of this book is to complement the existing literature in introductory real and functional analysis at the graduate level with a variety of conceptual problems (1,457 in total), ranging from easily accessible to thought provoking, mixing the practical and the theoretical aspects of the subject. Problems are grouped into ten chapters covering the main topics usually taught in courses on real and functional analysis. Each of these chapters opens with a brief reader's guide stating the needed definitions and basic results in the area and closes with a short description of the problems. The Problem chapters are accompanied by Solution chapters, which include solutions to two-thirds of the problems. Students can expect the solutions to be written in ...

  8. Introduction to measure theory and functional analysis

    CERN Document Server

    Cannarsa, Piermarco

    2015-01-01

    This book introduces readers to theories that play a crucial role in modern mathematics, such as integration and functional analysis, employing a unifying approach that views these two subjects as being deeply intertwined. This feature is particularly evident in the broad range of problems examined, the solutions of which are often supported by generous hints. If the material is split into two courses, it can be supplemented by additional topics from the third part of the book, such as functions of bounded variation, absolutely continuous functions, and signed measures. This textbook addresses the needs of graduate students in mathematics, who will find the basic material they will need in their future careers, as well as those of researchers, who will appreciate the self-contained exposition which requires no other preliminaries than basic calculus and linear algebra.

  9. Functional data analysis of generalized regression quantiles

    KAUST Repository

    Guo, Mengmeng

    2013-11-05

    Generalized regression quantiles, including the conditional quantiles and expectiles as special cases, are useful alternatives to the conditional means for characterizing a conditional distribution, especially when the interest lies in the tails. We develop a functional data analysis approach to jointly estimate a family of generalized regression quantiles. Our approach assumes that the generalized regression quantiles share some common features that can be summarized by a small number of principal component functions. The principal component functions are modeled as splines and are estimated by minimizing a penalized asymmetric loss measure. An iterative least asymmetrically weighted squares algorithm is developed for computation. While separate estimation of individual generalized regression quantiles usually suffers from large variability due to lack of sufficient data, by borrowing strength across data sets, our joint estimation approach significantly improves the estimation efficiency, which is demonstrated in a simulation study. The proposed method is applied to data from 159 weather stations in China to obtain the generalized quantile curves of the volatility of the temperature at these stations. © 2013 Springer Science+Business Media New York.

  10. Computer assistance in clinical functional analysis.

    Science.gov (United States)

    Ahlers, M O; Jakstat, H A

    2002-10-01

    The use of computers in the dental practice has been primarily restricted to the acquisition of billing data. Additional possibilities for use of PCs exist in diagnostic data acquisition and evaluation; clinical functional analysis seems a particularly suitable application. Such software is now available: CMDfact. Dentally, it is based on a previously developed and published examination and documentation system, the graphic user interface of which is used in the newly developed software. After the examination data have been acquired by mouse click or numerical entry, these are available for evaluation. A special function, the "Diagnosis pilot" is integrated to support the user. This helps in the assignment of the appropriate "Initial diagnoses", since it brings together the individually existing principal symptoms and suitable diagnoses for the initial diagnosis in question and also states which diagnoses "would be appropriate" for this, but are not available. With 3D animation, the software also helps the dentist to explain aspects of CMD to patients. The software also assists the dentist with a detailed multimedia help system, which provides context-sensitive help for every examination step. These help functions explain the sense of the relevant examinations, their performance and evaluation in the form of short texts and explanatory photographs and videos.

  11. Functional data analysis in forecasting Serbian fertility

    Directory of Open Access Journals (Sweden)

    Nikitović Vladimir

    2011-01-01

    Full Text Available A new approach, combining functional data analysis and principal components decomposition in order to forecasting demographic rates, introduced recently by Hyndman and his associates, is tested on official data series of Serbian age-specific fertility rates available for period 1950-2009. The original concept of the method with its extensions and improvements is applied to region-specific data for the country (Central Serbia and Vojvodina. One of the most important benefits of the method reflected in confirmation that is essentially to model and forecast more than one principal component in order to adequately address sources of variation in fertility. Similarly, modelling and forecasting fertility rates with regards to age and not total fertility rates shows how important it is for the recognized tendency of postponing childbearing in Serbia to be included in coefficients of functional time series. Besides, the method is based completely on evaluation of historical data, without subjective views of forecasters having to be taken into account. Coherent functional product ratio forecasts of two regions proved to be highly convergent on the long-term not allowing for outliers to contaminate the forecast.

  12. The Concurrent Validity of the Diagnostic Analysis of Reading Errors as a Predictor of the English Achievement of Lebanese Students.

    Science.gov (United States)

    Saigh, Philip A.; Khairallah, Shereen

    1983-01-01

    The concurrent validity of the Diagnostic Analysis of Reading Errors (DARE) subtests was studied, based on the responses of Lebanese secondary and postsecondary students relative to their achievement in an English course or on a standardized test of English proficiency. The results indicate that the DARE is not a viable predictor of English…

  13. Longitudinal Analysis of the Role of Perceived Self-Efficacy for Self-Regulated Learning in Academic Continuance and Achievement

    Science.gov (United States)

    Caprara, Gian Vittorio; Fida, Roberta; Vecchione, Michele; Del Bove, Giannetta; Vecchio, Giovanni Maria; Barbaranelli, Claudio; Bandura, Albert

    2008-01-01

    The present study examined the developmental course of perceived efficacy for self-regulated learning and its contribution to academic achievement and likelihood of remaining in school in a sample of 412 Italian students (48% males and 52% females ranging in age from 12 to 22 years). Latent growth curve analysis revealed a progressive decline in…

  14. Effects of a Gluten-Free Diet on Rate of Achievement in Autistic Children in an Applied Behavioral Analysis Program.

    Science.gov (United States)

    Gemmell, Melissa; Chambliss, Catherine

    This study used both between-subjects and within-subjects analyses to examine the effects of a gluten-free diet on the academic achievement of autistic children. The between-subjects analysis included data from eight autistic children (ages 5 to 7) with four on a gluten-free diet and four serving as controls. The number of attempts needed before…

  15. Exploring the Peer Interaction Effects on Learning Achievement in a Social Learning Platform Based on Social Network Analysis

    Science.gov (United States)

    Lin, Yu-Tzu; Chen, Ming-Puu; Chang, Chia-Hu; Chang, Pu-Chen

    2017-01-01

    The benefits of social learning have been recognized by existing research. To explore knowledge distribution in social learning and its effects on learning achievement, we developed a social learning platform and explored students' behaviors of peer interactions by the proposed algorithms based on social network analysis. An empirical study was…

  16. Effects of Computer Applications on Elementary School Students' Achievement: A Meta-Analysis of Students in Taiwan

    Science.gov (United States)

    Liao, Yuen-kuang Cliff; Chang, Huei-wen; Chen, Yu-wen

    2008-01-01

    A meta-analysis was performed to synthesize existing research comparing the effects of computer applications (i.e., computer-assisted instruction, computer simulations, and Web-based learning) versus traditional instruction on elementary school students' achievement in Taiwan. Forty-eight studies were located from four sources, and their…

  17. Does Hands-On Science Practices Make an Impact on Achievement in Science? A Meta-Analysis

    Science.gov (United States)

    Caglak, Serdar

    2017-01-01

    This study aimed to investigate to what extent the use of hands-on science activities influences on students? academic achievement in science. Review of literature revealed several research studies focusing upon such aim and thus, a meta-analysis of these researches was carried out to obtain an overall effect size estimate of hands-on science…

  18. Analysis of Learning Achievement and Teacher-Student Interactions in Flipped and Conventional Classrooms

    Science.gov (United States)

    Sun, Jerry Chih-Yuan; Wu, Yu-Ting

    2016-01-01

    This study aimed to investigate the effectiveness of two different teaching methods on learning effectiveness. OpenCourseWare was integrated into the flipped classroom model (experimental group) and distance learning (control group). Learning effectiveness encompassed learning achievement, teacher-student interactions, and learning satisfaction.…

  19. Analysis of Frequency of Tests and Varying Feedback Delays in College Mathematics Achievement

    Science.gov (United States)

    Townsend, Neal R.; Wheatley, Grayson H.

    1975-01-01

    Sixteen beginning analytic geometry and calculus classes (442 students) followed eight testing regimes for one academic quarter. Three aptitude subgroups were identified in each class. Classes to which daily quizzes were given achieved significantly higher on a specially constructed test than those which had only a single midterm examination.…

  20. A Time Lag Analysis of Temporal Relations between Motivation, Academic Achievement, and Two Cognitive Abilities

    Science.gov (United States)

    Greene, Monica R.; Pasnak, Robert; Romero, Sandy L.

    2009-01-01

    Research Findings: The present study employed a time lag design to assess temporal relationships between motivation, academic achievement, and cognitive development. Eighty-one children from 2 preschool programs were measured twice, with an 11-week time lag, on 2 measures of motivation (marble drop task, bean bag toss task), 2 measures of…

  1. Searching for the Golden Model of Education: Cross-National Analysis of Math Achievement

    Science.gov (United States)

    Bodovski, Katerina; Byun, Soo-yong; Chykina, Volha; Chung, Hee Jin

    2017-01-01

    We utilised four waves of TIMSS data in addition to the information we have collected on countries' educational systems to examine whether different degrees of standardisation, differentiation, proportion of students in private schools and governmental spending on education influence students' math achievement, its variation and socioeconomic…

  2. Analysis of achievable capacity in irregularly-placed high performance mesh nodes

    CSIR Research Space (South Africa)

    Olwal, TO

    2012-09-01

    Full Text Available challenge. This paper derives the achievable capacity limit of such HPNs’ placements. The analytical results show that the network capacity increases with the irregularity of HPNs placements, the number of antennas as well as the multiplicity of radios per...

  3. Efficacy of the Cooperative Learning Method on Mathematics Achievement and Attitude: A Meta-Analysis Research

    Science.gov (United States)

    Capar, Gulfer; Tarim, Kamuran

    2015-01-01

    This research compiles experimental studies from 1988 to 2010 that examined the influence of the cooperative learning method, as compared with that of traditional methods, on mathematics achievement and on attitudes towards mathematics. The related field was searched using the following key words in Turkish "matematik ve isbirlikli ögrenme,…

  4. Relationship between Educational Resources and School Achievement: A Mixed Method Intra-District Analysis

    Science.gov (United States)

    Jimenez-Castellanos, Oscar

    2010-01-01

    This study examines the relationship between educational resources (fiscal, personnel and facilities) and school achievement within a large urban/suburban elementary school district. A sequential mixed methods approach reveals inequitable resource allocation trends and patterns between schools within a school district by producing different…

  5. The Effects of Statistical Analysis Software and Calculators on Statistics Achievement

    Science.gov (United States)

    Christmann, Edwin P.

    2009-01-01

    This study compared the effects of microcomputer-based statistical software and hand-held calculators on the statistics achievement of university males and females. The subjects, 73 graduate students enrolled in univariate statistics classes at a public comprehensive university, were randomly assigned to groups that used either microcomputer-based…

  6. Gender Disparity Analysis in Academic Achievement at Higher Education Preparatory Schools: Case of South Wollo, Ethiopia

    Science.gov (United States)

    Eshetu, Amogne Asfaw

    2015-01-01

    Gender is among the determinant factors affecting students' academic achievement. This paper tried to investigate the impact of gender on academic performance of preparatory secondary school students based on 2014 EHEECE result. Ex post facto research design was used. To that end, data were collected from 3243 students from eight purposively…

  7. An Intuitive Analysis of the Impacts of Floods on Achieving MDGS in Pakistan

    Directory of Open Access Journals (Sweden)

    Abdul Hamid

    2011-09-01

    Full Text Available The aim of the study is to analyse the impacts of catastrophic floods of 2010 on achieving Millennium Development Goals (MDGs in Pakistan. Since 2006, Pakistan has been facing many obstacles in its way to achieve the MDGs, stemming from rise in insurgency, electricity crisis, a sudden meltdown of the global economy in 2008, along with a sharp rise in oil and food prices earlier in that year. The floods in 2010, have destroyed lives, houses, croplands and road infrastructure, causing enormous suffering and damages across an area the size of Italy. These damages have put the country to a state from where it may take decades to recoup. It has been estimated that approximately 20 million people in 78 districts in Pakistan have been affected. Moreover, 2,000 people died, cropped areas of 2 million hector and 2 million houses were also damaged. Standing crops, animal farms, livestock the major sources of income for rural families, have been destroyed causing further rise in the incidence of Poverty. Similarly, there is also likelihood that the destruction caused to schools, hospital, other infrastructure will also negatively affects the Pakistan’s performance regarding Health and Education related MDG indicators. Moreover, recent floods 2011 in Sindh will also have heavy toll on the economy and further aggravate the situation in achieving of MDGs in Pakistan. The study found that the impacts of disastrous flood were more severe in those districts which were already lagging behind in achieving MDGs.

  8. On Money and Motivation: A Quasi-Experimental Analysis of Financial Incentives for College Achievement

    Science.gov (United States)

    Scott-Clayton, Judith

    2011-01-01

    Programs linking college aid to academic achievement could work either by lowering the cost of college or by inducing additional student effort. I examine the PROMISE program in West Virginia, which offers free tuition to students who maintain a minimum GPA and course load. Using administrative data, I exploit discontinuities in the eligibility…

  9. Financial Aid Tipping Points: An Analysis of Aid and Academic Achievement at a California Community College

    Science.gov (United States)

    Coria, Elizabeth; Hoffman, John L.

    2016-01-01

    The purpose of this study was to explore relationships between financial aid awards and measures of student academic achievement. Financial aid and academic records for 11,956 students attending an urban California community college were examined and analyzed using simultaneous linear regression and two-way factorial ANOVAs. Findings revealed a…

  10. A meta-analysis of the impact of situationally induced achievement goals on task performance

    NARCIS (Netherlands)

    Van Yperen, Nico W.; Blaga, Monica; Postmes, Thomas

    2015-01-01

    The purpose of this research was to meta-analyze studies which experimentally induced an achieve- ment goal state to examine its causal effect on the individual’s performance at the task at hand, and to investigate the moderator effects of feedback anticipation and time pressure. The data set compri

  11. Factors Predicting Science Achievement of Immigrant and Non-Immigrant Students: A Multilevel Analysis

    Science.gov (United States)

    Areepattamannil, Shaljan; Kaur, Berinderjeet

    2013-01-01

    This study, employing hierarchical linear modeling (HLM), sought to investigate the student-level and school-level factors associated with the science achievement of immigrant and non-immigrant students among a national sample of 22,646 students from 896 schools in Canada. While student background characteristics such as home language, family…

  12. Parent Involvement and Science Achievement: A Cross-Classified Multilevel Latent Growth Curve Analysis

    Science.gov (United States)

    Johnson, Ursula Y.; Hull, Darrell M.

    2014-01-01

    The authors examined science achievement growth at Grades 3, 5, and 8 and parent school involvement at the same time points using the Early Childhood Longitudinal Study-Kindergarten Class of 1998-1999. Data were analyzed using cross-classified multilevel latent growth curve modeling with time invariant and varying covariates. School-based…

  13. Achievement Goal Orientations and Subjective Well-Being: A Person-Centred Analysis

    Science.gov (United States)

    Tuominen-Soini, Heta; Salmela-Aro, Katariina; Niemivirta, Markku

    2008-01-01

    This study examined whether students with different achievement goal orientation profiles differ in terms of subjective well-being (i.e., self-esteem, depressive symptoms, school-related burnout, and educational goal appraisals). Six groups of students with unique motivational profiles were identified. Observed differences in subjective well-being…

  14. Transfer function analysis of thermospheric perturbations

    Science.gov (United States)

    Mayr, H. G.; Harris, I.; Varosi, F.; Herrero, F. A.; Spencer, N. W.

    1986-01-01

    Applying perturbation theory, a spectral model in terms of vectors spherical harmonics (Legendre polynomials) is used to describe the short term thermospheric perturbations originating in the auroral regions. The source may be Joule heating, particle precipitation or ExB ion drift-momentum coupling. A multiconstituent atmosphere is considered, allowing for the collisional momentum exchange between species including Ar, O2, N2, O, He and H. The coupled equations of energy, mass and momentum conservation are solved simultaneously for the major species N2 and O. Applying homogeneous boundary conditions, the integration is carred out from the Earth's surface up to 700 km. In the analysis, the spherical harmonics are treated as eigenfunctions, assuming that the Earth's rotation (and prevailing circulation) do not significantly affect perturbations with periods which are typically much less than one day. Under these simplifying assumptions, and given a particular source distribution in the vertical, a two dimensional transfer function is constructed to describe the three dimensional response of the atmosphere. In the order of increasing horizontal wave numbers (order of polynomials), this transfer function reveals five components. To compile the transfer function, the numerical computations are very time consuming (about 100 hours on a VAX for one particular vertical source distribution). However, given the transfer function, the atmospheric response in space and time (using Fourier integral representation) can be constructed with a few seconds of a central processing unit. This model is applied in a case study of wind and temperature measurements on the Dynamics Explorer B, which show features characteristic of a ringlike excitation source in the auroral oval. The data can be interpreted as gravity waves which are focused (and amplified) in the polar region and then are reflected to propagate toward lower latitudes.

  15. The effects of functional group counseling on inspiring low-achieving students' self-worth and self-efficacy in Taiwan.

    Science.gov (United States)

    Hong, Zuway-R; Lin, Huann-shyang; Wang, Hsin-Hui; Chen, Hsiang-Ting; Yu, Tien-chi

    2012-01-01

    In this study, we investigated the effects of functional group counseling on inspiring low achievers' self-worth and self-efficacy in Taiwan. Forty-three 10th grade low-achieving students volunteered as the Experimental Group to join a 24-week intervention, which integrated and utilized functional group counseling; another 51 10th grade low-achieving students volunteered to be Comparison Group I. In addition, 43 10th grade moderate or high academic achieving students volunteered to be Comparison Group II. All participants completed the Vocational School Student Questionnaire at the beginning and end of this study to measure their self-worth and self-efficacy. In addition, six target students (two boys and four girls) with the lowest total scores on self-worth or self-efficacy in the pretest were selected from the Experimental Group to be interviewed at the end of the intervention and observed weekly. Analyses of variance, analyses of covariance, and paired t-tests assessed the similarity and differences among groups. The initial findings were as follows: Experimental group students had significantly higher scores on self-efficacy and self-worth than both Comparison Group I and Group II students and functional group counseling was shown to significantly affect the low-achieving students. Qualitative results from interviews and observations were used for triangulation and consolidation of quantitative results. Implications of the study included the recommended use of functional group counseling with low-achieving students.

  16. A Study of the Relationship between Historical Analysis and Student Achievement in Eighth Grade American History

    Science.gov (United States)

    Stuart, Kevin

    2010-01-01

    The purpose of this action research project was to study the relationship between Historical Analysis and student performance on the California Standards Test (CSTs), both English Language Arts and History, as well as to study the relationship between Historical Analysis and Reading Comprehension. It was believed that Historical Analysis required…

  17. Identification and functional analysis of healing regulators in Drosophila.

    Science.gov (United States)

    Álvarez-Fernández, Carmen; Tamirisa, Srividya; Prada, Federico; Chernomoretz, Ariel; Podhajcer, Osvaldo; Blanco, Enrique; Martín-Blanco, Enrique

    2015-01-01

    Wound healing is an essential homeostatic mechanism that maintains the epithelial barrier integrity after tissue damage. Although we know the overall steps in wound healing, many of the underlying molecular mechanisms remain unclear. Genetically amenable systems, such as wound healing in Drosophila imaginal discs, do not model all aspects of the repair process. However, they do allow the less understood aspects of the healing response to be explored, e.g., which signal(s) are responsible for initiating tissue remodeling? How is sealing of the epithelia achieved? Or, what inhibitory cues cancel the healing machinery upon completion? Answering these and other questions first requires the identification and functional analysis of wound specific genes. A variety of different microarray analyses of murine and humans have identified characteristic profiles of gene expression at the wound site, however, very few functional studies in healing regulation have been carried out. We developed an experimentally controlled method that is healing-permissive and that allows live imaging and biochemical analysis of cultured imaginal discs. We performed comparative genome-wide profiling between Drosophila imaginal cells actively involved in healing versus their non-engaged siblings. Sets of potential wound-specific genes were subsequently identified. Importantly, besides identifying and categorizing new genes, we functionally tested many of their gene products by genetic interference and overexpression in healing assays. This non-saturated analysis defines a relevant set of genes whose changes in expression level are functionally significant for proper tissue repair. Amongst these we identified the TCP1 chaperonin complex as a key regulator of the actin cytoskeleton essential for the wound healing response. There is promise that our newly identified wound-healing genes will guide future work in the more complex mammalian wound healing response.

  18. Identification and functional analysis of healing regulators in Drosophila.

    Directory of Open Access Journals (Sweden)

    Carmen Álvarez-Fernández

    Full Text Available Wound healing is an essential homeostatic mechanism that maintains the epithelial barrier integrity after tissue damage. Although we know the overall steps in wound healing, many of the underlying molecular mechanisms remain unclear. Genetically amenable systems, such as wound healing in Drosophila imaginal discs, do not model all aspects of the repair process. However, they do allow the less understood aspects of the healing response to be explored, e.g., which signal(s are responsible for initiating tissue remodeling? How is sealing of the epithelia achieved? Or, what inhibitory cues cancel the healing machinery upon completion? Answering these and other questions first requires the identification and functional analysis of wound specific genes. A variety of different microarray analyses of murine and humans have identified characteristic profiles of gene expression at the wound site, however, very few functional studies in healing regulation have been carried out. We developed an experimentally controlled method that is healing-permissive and that allows live imaging and biochemical analysis of cultured imaginal discs. We performed comparative genome-wide profiling between Drosophila imaginal cells actively involved in healing versus their non-engaged siblings. Sets of potential wound-specific genes were subsequently identified. Importantly, besides identifying and categorizing new genes, we functionally tested many of their gene products by genetic interference and overexpression in healing assays. This non-saturated analysis defines a relevant set of genes whose changes in expression level are functionally significant for proper tissue repair. Amongst these we identified the TCP1 chaperonin complex as a key regulator of the actin cytoskeleton essential for the wound healing response. There is promise that our newly identified wound-healing genes will guide future work in the more complex mammalian wound healing response.

  19. Divorce, approaches to learning, and children's academic achievement: a longitudinal analysis of mediated and moderated effects.

    Science.gov (United States)

    Anthony, Christopher J; DiPerna, James Clyde; Amato, Paul R

    2014-06-01

    Data from the Early Childhood Longitudinal Study--Kindergarten Cohort (ECLS-K) were used to test the hypothesis that approaches to learning (ATL) mediates the link between parental divorce and academic achievement. Fixed effects regression was utilized to test for mediation, and subsequent moderation analyses examining gender and age at time of divorce also were conducted. Results indicated that divorce was associated with less growth in test scores and that ATL mediated 18% and 12% of this association in reading and mathematics respectively. Parental divorce also was associated with larger negative effects for children who experienced divorce at an older age as well as for girls' mathematics test scores. These findings contribute to the understanding of the impact of parental divorce on children's academic achievement and underscore the importance of focusing on the variability of child outcomes following parental divorce.

  20. The Longitudinal Process of Early Parent Involvement on Student Achievement: A Path Analysis

    OpenAIRE

    Hayakawa, Momoko; Englund, Michelle M.; Warner-Richter, Mallory N.; Reynolds, Arthur J.

    2013-01-01

    This longitudinal study investigated the process whereby early parent involvement in preschool effects student achievement from kindergarten through 6th grade. Participants were 1,539 low-income, mainly African American children and their mothers, in the Chicago Longitudinal Study. Program children (N = 989) received one or two years of the Child-Parent Center (CPC) program – a preschool intervention that strongly promoted parents' development of parent involvement skills within the school an...

  1. Effects of Students' Beliefs on Mathematics and Achievement of University Students: Regression Analysis Approach

    Directory of Open Access Journals (Sweden)

    Velo Suthar

    2010-01-01

    Full Text Available Problem statement: At present, after almost more than 20-decades, Malaysia can boast of a solid national philosophy of education, despite tremendous struggles and hopes. The professional learning opportunities are necessary to enhance, support and sustain student's mathematics achievement. Approach: Empirical evidence had shown that student's belief in mathematics is crucial in meeting career aspiration. In addition mathematical beliefs are closely correlated to their mathematics achievement among university students. Results: The literature exposed that a few studies had been done on university undergraduates. The present study involves a sample of eighty-six university undergraduate students, who had completed a self-reported questionnaire related to student mathematical beliefs on three dimensions, viz-a-viz beliefs about mathematics, beliefs about importance of mathematics and beliefs on one's ability in mathematics. The reliability index, using the Cronbach's alpha was 0.86, indicating a high level of internal consistency. Records of achievement (GPA were obtained from the academic division, University Putra Malaysia. Based on these records, students were classified into the minor and major mathematics group. The authors examined student's mathematical beliefs based on a three dimensional logistic regression model estimation technique, appropriate for a survey design study. Conclusion/Recommendations: The results illustrated and identified significant relationships between student beliefs about importance of mathematics and beliefs on one's ability in mathematics with mathematics achievement. In addition, the Hosmer and Lemeshow test was non-significant with a chi-square of 8.46, p = 0.3, which indicated that there is a good model fit as the data did not significantly deviate from the model. The overall model, 77.9% of the sample was classified correctly.

  2. Systematic classification of unseeded batch crystallization systems for achievable shape and size analysis

    Science.gov (United States)

    Acevedo, David; Nagy, Zoltan K.

    2014-05-01

    The purpose of the current work is to develop a systematic classification scheme for crystallization systems considering simultaneous size and shape variations, and to study the effect of temperature profiles on the achievable final shape of crystals for various crystallization systems. A classification method is proposed based on the simultaneous consideration of the effect of temperature profiles on nucleation and growth rates of two different characteristic crystal dimensions. Hence the approach provides direct indication of the extent in which crystal shape may be controlled for a particular system class by manipulating the supersaturation. A multidimensional population balance model (PBM) was implemented for unseeded crystallization processes of four different compounds. The effect between the nucleation and growth mechanisms on the final aspect ratio (AR) was investigated and it was shown that for nucleation dominated systems the AR is independent of the supersaturation profile. The simulation results confirmed experimentally also show that most crystallization systems tend to achieve an equilibrium shape hence the variation in the aspect ratio that can be achieved by manipulating the supersaturation is limited, in particular when nucleation is also taken into account as a competing phenomenon.

  3. Approaches to learning as predictors of academic achievement: Results from a large scale, multi-level analysis

    DEFF Research Database (Denmark)

    Herrmann, Kim Jesper

    2017-01-01

    . Controlling for the effects of age, gender, and progression, we found that the students’ end-of-semester grade point averages were related negatively to a surface approach and positively to organised effort. Interestingly, the effect of the surface approach on academic achievement varied across programmes......The relationships between university students’ academic achievement and their approaches to learning and studying continuously attract scholarly attention. We report the results of an analysis in which multilevel linear modelling was used to analyse data from 3,626 Danish university students...

  4. Factors significantly related to science achievement of Malaysian middle school students: An analysis of TIMSS 1999 data

    Science.gov (United States)

    Mokshein, Siti Eshah

    The importance of science and technology in the global economy has led to growing emphasis on math and science achievement all over the world. In this study, I seek to identify variables at the student-level and school-level that account for the variation in science achievement of the eighth graders in Malaysia. Using the Third International Math and Science Study (TIMSS) 1999 for Malaysia, a series of HLM analysis was performed. Results indicate that (1) variation in overall science achievement is greater between schools than within schools; (2) both the selected student-level and school-level factors are Important in explaining the variation in the eight graders' achievement In science; (3) the selected student-level variables explain about 13% of the variation in students' achievement within schools, but as an aggregate, they account for a much larger proportion of the between-school variance; (4) the selected school-level variables account for about 55% of the variation between schools; (5) within schools, the effects of self-concept In science, awareness of the social implications of science, gender, and home educational resources are significantly related to achievement; (6) the effects of self-concept in science and awareness of social implications of science are significant even after controlling for the effects of SES; (7) between schools, the effects of the mean of home educational resources, mean of parents' education, mean of awareness of the social implications of science, and emphasis on conducting experiments are significantly related to achievement; (8) the effects of SES variables explain about 50% of the variation in the school means achievement; and (9) the effects of emphasis on conducting experiments on achievement are significant even after controlling for the effects of SES. Since it is hard to change the society, it is recommended that efforts to Improve science achievement be focused more at the school-level, concentrating on variables that

  5. Economic Analysis on Monetization of Soil Functions

    Institute of Scientific and Technical Information of China (English)

    Zenglei; XI; Shaoqing; ZHANG

    2013-01-01

    On the basis of making clear diversity characteristics of soil functions and multiple characteristics of income, this paper points out that the monetization of soil functions based functional maintenance and change decision process can be regarded as a game process of different utilization methods at the background of different functions. The balance of this game process will determine monetary value of soil functions. After understanding money and monetization concepts, it introduces that measurability and exchangeability of soil functions provide objective conditions for monetization of soil functions. Finally, it discusses that usefulness value of soil functions provide basis for monetization of soil functions.

  6. A complexity analysis of functional interpretations

    DEFF Research Database (Denmark)

    Hernest, Mircea-Dan; Kohlenbach, Ulrich

    2005-01-01

    Summary: We give a quantitative analysis of Gödel's functional     interpretation and its monotone variant. The two have been used     for the extraction of programs and numerical bounds as well as     for conservation results. They apply both to (semi-)intuitionistic     as well as (combined...... with negative translation) classical proofs.     The proofs may be formalized in systems ranging from weak base     systems to arithmetic and analysis (and numerous fragments of     these). We give upper bounds in basic proof data on the depth,     size, maximal type degree and maximal type arity...... of the extracted     terms as well as on the depth of the verifying proof. In all     cases terms of size linear in the size of the proof at input     can be extracted and the corresponding extraction algorithms     have cubic worst-time complexity. The verifying proofs have depth     linear in the depth...

  7. A Method of Clustering Components into Modules Based on Products' Functional and Structural Analysis

    Institute of Scientific and Technical Information of China (English)

    MENG Xiang-hui; JIANG Zu-hua; ZHENG Ying-fei

    2006-01-01

    Modularity is the key to improving the cost-variety trade-off in product development. To achieve the functional independency and structural independency of modules, a method of clustering components to identify modules based on functional and structural analysis was presented. Two stages were included in the method. In the first stage the products' function was analyzed to determine the primary level of modules. Then the objective function for modules identifying was formulated to achieve functional independency of modules. Finally the genetic algorithm was used to solve the combinatorial optimization problem in modules identifying to form the primary modules of products. In the second stage the cohesion degree of modules and the coupling degree between modules were analyzed. Based on this structural analysis the modular scheme was refined according to the thinking of structural independency. A case study on the gear reducer was conducted to illustrate the validity of the presented method.

  8. Tracking Undergraduate Student Achievement in a First-Year Physiology Course Using a Cluster Analysis Approach

    Science.gov (United States)

    Brown, S. J.; White, S.; Power, N.

    2015-01-01

    A cluster analysis data classification technique was used on assessment scores from 157 undergraduate nursing students who passed 2 successive compulsory courses in human anatomy and physiology. Student scores in five summative assessment tasks, taken in each of the courses, were used as inputs for a cluster analysis procedure. We aimed to group…

  9. Tracking Undergraduate Student Achievement in a First-Year Physiology Course Using a Cluster Analysis Approach

    Science.gov (United States)

    Brown, S. J.; White, S.; Power, N.

    2015-01-01

    A cluster analysis data classification technique was used on assessment scores from 157 undergraduate nursing students who passed 2 successive compulsory courses in human anatomy and physiology. Student scores in five summative assessment tasks, taken in each of the courses, were used as inputs for a cluster analysis procedure. We aimed to group…

  10. Induced Neural Stem Cells Achieve Long-Term Survival and Functional Integration in the Adult Mouse Brain

    Directory of Open Access Journals (Sweden)

    Kathrin Hemmer

    2014-09-01

    Full Text Available Differentiated cells can be converted directly into multipotent neural stem cells (i.e., induced neural stem cells [iNSCs]. iNSCs offer an attractive alternative to induced pluripotent stem cell (iPSC technology with regard to regenerative therapies. Here, we show an in vivo long-term analysis of transplanted iNSCs in the adult mouse brain. iNSCs showed sound in vivo long-term survival rates without graft overgrowths. The cells displayed a neural multilineage potential with a clear bias toward astrocytes and a permanent downregulation of progenitor and cell-cycle markers, indicating that iNSCs are not predisposed to tumor formation. Furthermore, the formation of synaptic connections as well as neuronal and glial electrophysiological properties demonstrated that differentiated iNSCs migrated, functionally integrated, and interacted with the existing neuronal circuitry. We conclude that iNSC long-term transplantation is a safe procedure; moreover, it might represent an interesting tool for future personalized regenerative applications.

  11. Analyzing Distributed Functions in an Integrated Hazard Analysis

    Science.gov (United States)

    Morris, A. Terry; Massie, Michael J.

    2010-01-01

    Large scale integration of today's aerospace systems is achievable through the use of distributed systems. Validating the safety of distributed systems is significantly more difficult as compared to centralized systems because of the complexity of the interactions between simultaneously active components. Integrated hazard analysis (IHA), a process used to identify unacceptable risks and to provide a means of controlling them, can be applied to either centralized or distributed systems. IHA, though, must be tailored to fit the particular system being analyzed. Distributed systems, for instance, must be analyzed for hazards in terms of the functions that rely on them. This paper will describe systems-oriented IHA techniques (as opposed to traditional failure-event or reliability techniques) that should be employed for distributed systems in aerospace environments. Special considerations will be addressed when dealing with specific distributed systems such as active thermal control, electrical power, command and data handling, and software systems (including the interaction with fault management systems). Because of the significance of second-order effects in large scale distributed systems, the paper will also describe how to analyze secondary functions to secondary functions through the use of channelization.

  12. Identification of Energy Efficiency Opportunities through Building Data Analysis and Achieving Energy Savings through Improved Controls

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, Srinivas; Taasevigen, Danny J.; Koran, Bill

    2014-09-04

    This chapter will highlight analysis techniques to identify energy efficiency opportunities to improve operations and controls. A free tool, Energy Charting and Metrics (ECAM), will be used to assist in the analysis of whole-building, sub-metered, and/or data from the building automation system (BAS). Appendix A describes the features of ECAM in more depth, and also provide instructions for downloading ECAM and all resources pertaining to using ECAM.

  13. Functional analysis of variance for association studies.

    Directory of Open Access Journals (Sweden)

    Olga A Vsevolozhskaya

    Full Text Available While progress has been made in identifying common genetic variants associated with human diseases, for most of common complex diseases, the identified genetic variants only account for a small proportion of heritability. Challenges remain in finding additional unknown genetic variants predisposing to complex diseases. With the advance in next-generation sequencing technologies, sequencing studies have become commonplace in genetic research. The ongoing exome-sequencing and whole-genome-sequencing studies generate a massive amount of sequencing variants and allow researchers to comprehensively investigate their role in human diseases. The discovery of new disease-associated variants can be enhanced by utilizing powerful and computationally efficient statistical methods. In this paper, we propose a functional analysis of variance (FANOVA method for testing an association of sequence variants in a genomic region with a qualitative trait. The FANOVA has a number of advantages: (1 it tests for a joint effect of gene variants, including both common and rare; (2 it fully utilizes linkage disequilibrium and genetic position information; and (3 allows for either protective or risk-increasing causal variants. Through simulations, we show that FANOVA outperform two popularly used methods - SKAT and a previously proposed method based on functional linear models (FLM, - especially if a sample size of a study is small and/or sequence variants have low to moderate effects. We conduct an empirical study by applying three methods (FANOVA, SKAT and FLM to sequencing data from Dallas Heart Study. While SKAT and FLM respectively detected ANGPTL 4 and ANGPTL 3 associated with obesity, FANOVA was able to identify both genes associated with obesity.

  14. A Panel Analysis of Student Mathematics Achievement in the US in the 1990s: Does Increasing the Amount of Time in Learning Activities Affect Math Achievement?

    Science.gov (United States)

    Aksoy, Tevfik; Link, Charles R.

    2000-01-01

    Uses panel estimation techniques to estimate econometric models of mathematics achievement determinants for a nationally representative sample of high-school students. Extra time spent on math homework increases test scores; an extra hour of TV viewing negatively affects scores. Longer math periods also help. (Contains 56 references.) (MLH)

  15. Some Supplementary Methods for the Analysis of the Delis-Kaplan Executive Function System

    Science.gov (United States)

    Crawford, John R.; Garthwaite, Paul H.; Sutherland, David; Borland, Nicola

    2011-01-01

    Supplementary methods for the analysis of the Delis-Kaplan Executive Function System (Delis, Kaplan, & Kramer, 2001) are made available, including (a) quantifying the number of abnormally low achievement scores exhibited by an individual and accompanying this with an estimate of the percentage of the normative population expected to exhibit at…

  16. A cost analysis of implementing a behavioral weight loss intervention in community mental health settings: Results from the ACHIEVE trial.

    Science.gov (United States)

    Janssen, Ellen M; Jerome, Gerald J; Dalcin, Arlene T; Gennusa, Joseph V; Goldsholl, Stacy; Frick, Kevin D; Wang, Nae-Yuh; Appel, Lawrence J; Daumit, Gail L

    2017-06-01

    In the ACHIEVE randomized controlled trial, an 18-month behavioral intervention accomplished weight loss in persons with serious mental illness who attended community psychiatric rehabilitation programs. This analysis estimates costs for delivering the intervention during the study. It also estimates expected costs to implement the intervention more widely in a range of community mental health programs. Using empirical data, costs were calculated from the perspective of a community psychiatric rehabilitation program delivering the intervention. Personnel and travel costs were calculated using time sheet data. Rent and supply costs were calculated using rent per square foot and intervention records. A univariate sensitivity analysis and an expert-informed sensitivity analysis were conducted. With 144 participants receiving the intervention and a mean weight loss of 3.4 kg, costs of $95 per participant per month and $501 per kilogram lost in the trial were calculated. In univariate sensitivity analysis, costs ranged from $402 to $725 per kilogram lost. Through expert-informed sensitivity analysis, it was estimated that rehabilitation programs could implement the intervention for $68 to $85 per client per month. Costs of implementing the ACHIEVE intervention were in the range of other intensive behavioral weight loss interventions. Wider implementation of efficacious lifestyle interventions in community mental health settings will require adequate funding mechanisms. © 2017 The Obesity Society.

  17. Introducing trimming and function ranking to Solid Works based on function analysis

    NARCIS (Netherlands)

    Chechurin, Leonid S.; Wits, Wessel W.; Bakker, Hans M.; Vaneker, Tom H.J.; Cascini, G.; Vaneker, T.H.J.

    2011-01-01

    TRIZ based Function Analysis models existing products based on functional interactions between product parts. Such a function model description is the ideal starting point for product innovation. Design engineers can apply (TRIZ) methods such as trimming and function ranking to this function model t

  18. Introducing Trimming and Function Ranking to SolidWorks based on Function Analysis

    NARCIS (Netherlands)

    Chechurin, L.S.; Wits, W.W.; Bakker, H.M.; Vaneker, T.H.J.

    2015-01-01

    TRIZ based Function Analysis models existing products based on functional interactions between product parts. Such a function model description is the ideal starting point for product innovation. Design engineers can apply (TRIZ) methods such as trimming and function ranking to this function model t

  19. Introducing Trimming and Function Ranking to SolidWorks based on Function Analysis

    NARCIS (Netherlands)

    Chechurin, L.S.; Wits, Wessel Willems; Bakker, Hans M.; Vaneker, Thomas H.J.

    2015-01-01

    TRIZ based Function Analysis models existing products based on functional interactions between product parts. Such a function model description is the ideal starting point for product innovation. Design engineers can apply (TRIZ) methods such as trimming and function ranking to this function model

  20. A Meta-Analysis: The Relationship between Father Involvement and Student Academic Achievement

    Science.gov (United States)

    Jeynes, William H.

    2015-01-01

    A meta-analysis was undertaken, including 66 studies, to determine the relationship between father involvement and the educational outcomes of urban school children. Statistical analyses were done to determine the overall impact and specific components of father involvement. The possible differing effects of paternal involvement by race were also…

  1. The Impact of Guided Notes on Post-Secondary Student Achievement: A Meta-Analysis

    Science.gov (United States)

    Larwin, Karen H.; Larwin, David A.

    2013-01-01

    The common practice of using of guided notes in the post-secondary classroom is not fully appreciated or understood. In an effort to add to the existing research about this phenomenon, the current investigation expands on previously published research and one previously published meta-analysis that examined the impact of guided notes on…

  2. Determinants of Educational Achievement in Morocco: A Micro-Econometric Analysis Applied to the TIMSS Study

    Science.gov (United States)

    Ibourk, Aomar

    2013-01-01

    Based on data from international surveys measuring learning (TIMSS), this article focuses on the analysis of the academic performance Moroccan students. The results of the econometric model show that the students' characteristics, their family environment and school context are key determinants of these performances. The study also shows that the…

  3. A decision Enhancement Service for Stakeholder Analysis to Achieve Transformations in the Public Sector

    NARCIS (Netherlands)

    Knol, Arjan; Janssen, Marijn; Sol, H G

    2015-01-01

    Sourcing has become a popular practice for public sector managers aiming for transformations to save costs and improve service delivery. Nevertheless, public sector sourcing often fails due to stakeholder resistance and power struggles, stressing the need for stakeholder analysis. This paper present

  4. Trend Analysis on Mathematics Achievements: A Comparative Study Using TIMSS Data

    Science.gov (United States)

    Ker, H. W.

    2013-01-01

    Research addressed the importance of mathematics education for the students' preparation to enter scientific and technological workforce. This paper utilized Trends in International Mathematics and Science Study (TIMSS) 2011 data to conduct a global comparative analysis on mathematics performance at varied International Benchmark levels. The…

  5. Advanced functionality for radio analysis in the Offline software framework of the Pierre Auger Observatory

    CERN Document Server

    Abreu, P; Ahn, E J; Albuquerque, I F M; Allard, D; Allekotte, I; Allen, J; Allison, P; Castillo, J Alvarez; Alvarez-Muñiz, J; Ambrosio, M; Aminaei, A; Anchordoqui, L; Andringa, S; Antičić, T; Aramo, C; Arganda, E; Arqueros, F; Asorey, H; Assis, P; Aublin, J; Ave, M; Avenier, M; Avila, G; Bäcker, T; Balzer, M; Barber, K B; Barbosa, A F; Bardenet, R; Barroso, S L C; Baughman, B; Beatty, J J; Becker, B R; Becker, K H; Bellido, J A; BenZvi, S; Berat, C; Bertou, X; Biermann, P L; Billoir, P; Blanco, F; Blanco, M; Bleve, C; Blümer, H; Boháčová, M; Boncioli, D; Bonifazi, C; Bonino, R; Borodai, N; Brack, J; Brogueira, P; Brown, W C; Bruijn, R; Buchholz, P; Bueno, A; Burton, R E; Caballero-Mora, K S; Caramete, L; Caruso, R; Castellina, A; Cataldi, G; Cazon, L; Cester, R; Chauvin, J; Chiavassa, A; Chinellato, J A; Chou, A; Chudoba, J; Clay, R W; Coluccia, M R; Conceição, R; Contreras, F; Cook, H; Cooper, M J; Coppens, J; Cordier, A; Cotti, U; Coutu, S; Covault, C E; Creusot, A; Criss, A; Cronin, J; Curutiu, A; Dagoret-Campagne, S; Dallier, R; Dasso, S; Daumiller, K; Dawson, B R; de Almeida, R M; De Domenico, M; De Donato, C; de Jong, S J; De La Vega, G; Junior, W J M de Mello; Neto, J R T de Mello; De Mitri, I; de Souza, V; de Vries, K D; Decerprit, G; del Peral, L; Deligny, O; Dembinski, H; Denkiewicz, A; Di Giulio, C; Diaz, J C; Castro, M L Díaz; Diep, P N; Dobrigkeit, C; D'Olivo, J C; Dong, P N; Dorofeev, A; Anjos, J C dos; Dova, M T; D'Urso, D; Dutan, I; Ebr, J; Engel, R; Erdmann, M; Escobar, C O; Etchegoyen, A; Luis, P Facal San; Falcke, H; Farrar, G; Fauth, A C; Fazzini, N; Ferguson, A P; Ferrero, A; Fick, B; Filevich, A; Filipčič, A; Fliescher, S; Fracchiolla, C E; Fraenkel, E D; Fröhlich, U; Fuchs, B; Gamarra, R F; Gambetta, S; García, B; Gámez, D García; Garcia-Pinto, D; Gascon, A; Gemmeke, H; Gesterling, K; Ghia, P L; Giaccari, U; Giller, M; Glass, H; Gold, M S; Golup, G; Albarracin, F Gomez; Berisso, M Gómez; Gonçalves, P; Gonzalez, D; Gonzalez, J G; Gookin, B; Góra, D; Gorgi, A; Gouffon, P; Gozzini, S R; Grashorn, E; Grebe, S; Griffith, N; Grigat, M; Grillo, A F; Guardincerri, Y; Guarino, F; Guedes, G P; Hague, J D; Hansen, P; Harari, D; Harmsma, S; Harton, J L; Haungs, A; Hebbeker, T; Heck, D; Herve, A E; Hojvat, C; Holmes, V C; Homola, P; Hörandel, J R; Horneffer, A; Hrabovský, M; Huege, T; Insolia, A; Ionita, F; Italiano, A; Jiraskova, S; Kadija, K; Kampert, K H; Karhan, P; Karova, T; Kasper, P; Kégl, B; Keilhauer, B; Keivani, A; Kelley, J L; Kemp, E; Kieckhafer, R M; Klages, H O; Kleifges, M; Kleinfeller, J; Knapp, J; Koang, D -H; Kotera, K; Krohm, N; Krömer, O; Kruppke-Hansen, D; Kuehn, F; Kuempel, D; Kulbartz, J K; Kunka, N; La Rosa, G; Lachaud, C; Lautridou, P; Leão, M S A B; Lebrun, D; Lebrun, P; de Oliveira, M A Leigui; Lemiere, A; Letessier-Selvon, A; Lhenry-Yvon, I; Link, K; López, R; Agüera, A Lopez; Louedec, K; Bahilo, J Lozano; Lucero, A; Ludwig, M; Lyberis, H; Macolino, C; Maldera, S; Mandat, D; Mantsch, P; Mariazzi, A G; Marin, V; Maris, I C; Falcon, H R Marquez; Marsella, G; Martello, D; Martin, L; Bravo, O Martínez; Mathes, H J; Matthews, J; Matthews, J A J; Matthiae, G; Maurizio, D; Mazur, P O; Medina-Tanco, G; Melissas, M; Melo, D; Menichetti, E; Menshikov, A; Mertsch, P; Meurer, C; Mičanović, S; Micheletti, M I; Miller, W; Miramonti, L; Mollerach, S; Monasor, M; Ragaigne, D Monnier; Montanet, F; Morales, B; Morello, C; Moreno, E; Moreno, J C; Morris, C; Mostafá, M; Moura., C A; Mueller, S; Muller, M A; Müller, G; Münchmeyer, M; Mussa, R; Navarra, G; Navarro, J L; Navas, S; Necesal, P; Nellen, L; Nelles, A; Nhung, P T; Nierstenhoefer, N; Nitz, D; Nosek, D; Nožka, L; Nyklicek, M; Oehlschläger, J; Olinto, A; Oliva, P; Olmos-Gilbaja, V M; Ortiz, M; Pacheco, N; Selmi-Dei, D Pakk; Palatka, M; Pallotta, J; Palmieri, N; Parente, G; Parizot, E; Parra, A; Parrisius, J; Parsons, R D; Pastor, S; Paul, T; Pech, M; Pȩkala, J; Pelayo, R; Pepe, I M; Perrone, L; Pesce, R; Petermann, E; Petrera, S; Petrinca, P; Petrolini, A; Petrov, Y; Petrovic, J; Pfendner, C; Phan, N; Piegaia, R; Pierog, T; Pieroni, P; Pimenta, M; Pirronello, V; Platino, M; Ponce, V H; Pontz, M; Privitera, P; Prouza, M; Quel, E J; Rautenberg, J; Ravel, O; Ravignani, D; Revenu, B; Ridky, J; Risse, M; Ristori, P; Rivera, H; Rivière, C; Rizi, V; Robledo, C; de Carvalho, W Rodrigues; Rodriguez, G; Martino, J Rodriguez; Rojo, J Rodriguez; Rodriguez-Cabo, I; Rodríguez-Frías, M D; Ros, G; Rosado, J; Rossler, T; Roth, M; Rouillé-d'Orfeuil, B; Roulet, E; Rovero, A C; Rühle, C; Salamida, F; Salazar, H; Salina, G; Sánchez, F; Santander, M; Santo, C E; Santos, E; Santos, E M; Sarazin, F; Sarkar, S; Sato, R; Scharf, N; Scherini, V; Schieler, H; Schiffer, P; Schmidt, A; Schmidt, F; Schmidt, T; Scholten, O; Schoorlemmer, H; Schovancova, J; Schovánek, P; Schroeder, F; Schulte, S; Schuster, D; Sciutto, S J; Scuderi, M; Segreto, A; Semikoz, D; Settimo, M; Shadkam, A; Shellard, R C; Sidelnik, I; Sigl, G; Śmiałkowski, A; Šmída, R; Snow, G R; Sommers, P; Sorokin, J; Spinka, H; Squartini, R; Stapleton, J; Stasielak, J; Stephan, M; Stutz, A; Suarez, F; Suomijärvi, T; Supanitsky, A D; Šuša, T; Sutherland, M S; Swain, J; Szadkowski, Z; Szuba, M; Tamashiro, A; Tapia, A; Taşcău, O; Tcaciuc, R; Tegolo, D; Thao, N T; Thomas, D; Tiffenberg, J; Timmermans, C; Tiwari, D K; Tkaczyk, W; Peixoto, C J Todero; Tomé, B; Tonachini, A; Travnicek, P; Tridapalli, D B; Tristram, G; Trovato, E; Tueros, M; Ulrich, R; Unger, M; Urban, M; Galicia, J F Valdés; Valiño, I; Valore, L; Berg, A M van den; Cárdenas, B Vargas; Vázquez, J R; Vázquez, R A; Veberič, D; Verzi, V; Videla, M; Villaseñor, L; Wahlberg, H; Wahrlich, P; Wainberg, O; Warner, D; Watson, A A; Weber, M; Weidenhaupt, K; Weindl, A; Westerhoff, S; Whelan, B J; Wieczorek, G; Wiencke, L; Wilczyńska, B; Wilczyński, H; Will, M; Williams, C; Winchen, T; Winders, L; Winnick, M G; Wommer, M; Wundheiler, B; Yamamoto, T; Younk, P; Yuan, G; Zamorano, B; Zas, E; Zavrtanik, D; Zavrtanik, M; Zaw, I; Zepeda, A; Ziolkowski, M; 10.1016/j.nima.2011.01.049

    2011-01-01

    The advent of the Auger Engineering Radio Array (AERA) necessitates the development of a powerful framework for the analysis of radio measurements of cosmic ray air showers. As AERA performs "radio-hybrid" measurements of air shower radio emission in coincidence with the surface particle detectors and fluorescence telescopes of the Pierre Auger Observatory, the radio analysis functionality had to be incorporated in the existing hybrid analysis solutions for fluoresence and surface detector data. This goal has been achieved in a natural way by extending the existing Auger Offline software framework with radio functionality. In this article, we lay out the design, highlights and features of the radio extension implemented in the Auger Offline framework. Its functionality has achieved a high degree of sophistication and offers advanced features such as vectorial reconstruction of the electric field, advanced signal processing algorithms, a transparent and efficient handling of FFTs, a very detailed simulation of...

  6. FACTOR ANALYSIS ABOUT EXCLUSIVE BREASTFEEDING ACHIEVEMENT LEVEL AMONG MOTHERS WHO PROVIDE BREASTMILK TO THEIR CHILDREN

    Directory of Open Access Journals (Sweden)

    Tiyas Kusumaningrum

    2017-04-01

    Full Text Available Introduction: The number of mother who breastfeed their babies exclusively in Indonesia is low. It caused by many factors such as high intensity of formula milk advertisement, lack of awareness about the importance of breastfeeding, working mother, social culture, family support and the role of health care provider. The purpose of this research was to analyze factors related with successfulness level of exclusive breastfeeding. Method: Design used in this research was analytic retrospective. The population were all mothers at Pacarkeling Public Health Center area. Sample obtained through purposive sampling. Total sample was 61 respondents. Independent variables were knowledge, information and promotion, family support, social cultural, role of health provider, work/occupation, education and breast physiology anatomy. The dependent variable was exclusive breastfeeding. Result: The result indicated that exclusive breastfeeding achievement level was related with information and promotion (r = 0.271, family support (r = 373, health care provider role (r = 231, mother occupation (r = 251, anatomy and physiology of breast (r = 293, while the knowledge (r = 108, social cultural (r = 180 and education (r = 093 not significantly related. Discussion: In conclusion, there was a positive correlation between information and promotion, family support, health care provider role, mother’s occupation, anatomy and physiology of breast with successfulness level of exclusive breastfeeding. While the knowledge, social cultural and education did not indicate significant result. Therefore it is suggested to increase the quantity and quality of information and promotion about exclusive breastfeeding to the society, health care provider and pregnant and breastfeeding mother.

  7. Analysis of Discrete Mittag - Leffler Functions

    Directory of Open Access Journals (Sweden)

    N. Shobanadevi

    2015-03-01

    Full Text Available Discrete Mittag - Leffler functions play a major role in the development of the theory of discrete fractional calculus. In the present article, we analyze qualitative properties of discrete Mittag - Leffler functions and establish sufficient conditions for convergence, oscillation and summability of the infinite series associated with discrete Mittag - Leffler functions.

  8. Science Learning: A path analysis of its links with reading comprehension, question-asking in class and science achievement

    Science.gov (United States)

    Cano, Francisco; García, Ángela; Berbén, A. B. G.; Justicia, Fernando

    2014-07-01

    The purpose of this research was to build and test a conceptual model of the complex interrelationships between students' learning in science (learning approaches and self-regulation), their reading comprehension, question-asking in class and science achievement. These variables were measured by means of a test and a series of questionnaires administered to 604 ninth-grade students, and the data collected were analysed using a correlational, cross-sectional design. Results of a path analysis indicated that (a) students' self-regulated and intentional knowledge-constructing activity (self-regulated strategy use, deep approach and knowledge-building) were what chiefly accounted for their question-asking in class; (b) question-asking (high and low levels) was related directly to reading comprehension and indirectly, through its contribution to the this, to academic achievement; (c) reading comprehension was directly and negatively associated with surface approach and indirectly and positively related to deep approach and knowledge-building; and (d) some of these variables, particularly reading comprehension, accounted for academic achievement in science. This model explained nearly 30% of the variance in academic achievement and provided a substantial and distinctive insight into the web of interrelationships among these variables. Implications for future research and science teaching and learning are discussed (e.g. the importance of supporting students' efforts to learn science in a meaningful, active and self-regulated way and of improving their reading comprehension).

  9. An analysis of science conceptual knowledge in journals of students with disabilities and normally achieving students

    Science.gov (United States)

    Grigg, Gail S.

    Science education reforms of the last two decades have focused on raising the bar for ALL students which includes students with mild to moderate disabilities. Formative assessment can be used to assess the progress of these students to inquire, understand scientific concepts, reason scientifically, make decisions, and communicate effectively in science. The purpose of this study is to examine the use of science journals as a formative assessment in a guided inquiry unit of study for students with learning disabilities. Two normally achieving students (NA) and five students with learning disabilities (SLD) participated in a study of mammals that utilized journals to record the development of student knowledge through the course of study. Students were interviewed after the lessons were complete using the same prompts required in the journals. Themes were developed from the student writings and their verbal discourse using Grounded Theory. Journals and verbal discourse were rated following the themes of Knowledge Telling (KT) and Knowledge Transformation (KTR). Concept maps were developed for the Pre and Post test lessons (written and verbal discourses) by the raters in an attempt to further explain the knowledge that the students conveyed. The results of this study suggest that SLD are able to demonstrate knowledge about mammals better through verbal discourse than written discourse. While the NA students wrote more and used more technical discourse than did their SLD peers, the conceptual understanding of the topic by the SLD was no less inclusive than their NA peers when accessed verbally. The journals demonstrated limited conceptual growth for the SLD. Further, while lexical density is important to the development of knowledge in science, this study suggests the "conceptual density" may be another important indicator to examine.

  10. A boundary value problem for hypermonogenic functions in Clifford analysis

    Institute of Scientific and Technical Information of China (English)

    QIAO; Yuying

    2005-01-01

    This paper deals with a boundary value problem for hypermonogenic functions in Clifford analysis. Firstly we discuss integrals of quasi-Cauchy's type and get the Plemelj formula for hypermonogenic functions in Clifford analysis, and then we address Riemman boundary value problem for hypermonogenic functions.

  11. Memory-efficient analysis of dense functional connectomes

    Directory of Open Access Journals (Sweden)

    Kristian Loewe

    2016-11-01

    Full Text Available The functioning of the human brain relies on the interplay and integration of numerous individual units within a complex network. To identify network configurations characteristic of specific cognitive tasks or mental illnesses, functional connectomes can be constructed based on the assessment of synchronous fMRI activity at separate brain sites, and then analyzed using graph-theoretical concepts. In most previous studies, relatively coarse parcellations of the brain were used to define regions as graphical nodes. Such parcellated connectomes are highly dependent on parcellation quality because regional and functional boundaries need to be relatively consistent for the results to be interpretable. In contrast, dense connectomes are not subject to this limitation, since the parcellation inherent to the data is used to define graphical nodes, also allowing for a more detailed spatial mapping of connectivity patterns. However, dense connectomes are associated with considerable computational demands in terms of both time and memory requirements. The memory required to explicitly store dense connectomes in main memory can render their analysis infeasible, especially when considering high-resolution data or analyses across multiple subjects or conditions. Here, we present an object-based matrix representation that achieves a very low memory footprint by computing matrix elements on demand instead of explicitly storing them. In doing so, memory required for a dense connectome is reduced to the amount needed to store the underlying time series data. Based on theoretical considerations and benchmarks, different matrix object implementations and additional programs (based on available Matlab functions and Matlab-based third-party software are compared with regard to their computational efficiency in terms of memory requirements and computation time. The matrix implementation based on on-demand computations has very low memory requirements thus enabling

  12. Comparative analysis of fabrication methods for achieving rounded microchannels in PDMS

    Science.gov (United States)

    Bartlett, Nicholas W.; Wood, Robert J.

    2016-11-01

    Many microfluidic applications demand control over channel cross-sectional geometry. In particular, rounded microchannels are essential to the function of microfluidic valves, which have played an integral part in the success of microfluidics over the past fifteen years. Here we investigate the relative strengths and weaknesses of different strategies for fabricating rounded microchannels in PDMS, systematically examining five common strategies. We consider the appropriateness of the fabrication strategies for microchannels of differing sizes and aspect ratios, and evaluate these various strategies on a number of metrics ranging from microchannel resolution to fabrication difficulty. We discuss the merits of the different strategies for a range of applications, and make recommendations on which strategy to use based on the driving constraints of the device.

  13. Achieving Both Valid and Secure Logistic Regression Analysis on Aggregated Data from Different Private Sources

    CERN Document Server

    Hall, Rob; Fienberg, Stephen

    2011-01-01

    Preserving the privacy of individual databases when carrying out statistical calculations has a long history in statistics and had been the focus of much recent attention in machine learning In this paper, we present a protocol for computing logistic regression when the data are held by separate parties without actually combining information sources by exploiting results from the literature on multi-party secure computation. We provide only the final result of the calculation compared with other methods that share intermediate values and thus present an opportunity for compromise of values in the combined database. Our paper has two themes: (1) the development of a secure protocol for computing the logistic parameters, and a demonstration of its performances in practice, and (2) and amended protocol that speeds up the computation of the logistic function. We illustrate the nature of the calculations and their accuracy using an extract of data from the Current Population Survey divided between two parties.

  14. Achievements of the ATLAS Distributed Analysis during the first run period

    CERN Document Server

    Farida, Fassi; The ATLAS collaboration

    2013-01-01

    Summary : In the LHC operations era analyzing the large data by the distributed physicists becomes a challenging task. The Computing Model of the ATLAS experiment at the LHC at CERN was designed around the concepts of grid computing. Large data volumes from the detectors and simulations require a large number of CPUs and storage space for data processing. To cope with these challenges a global network known as the Worlwide LHC Computing Grid (WLCG) was built. This is the most sophisticated data taking and analysis system ever built. Since the start of data-taking, the ATLAS Distributed Analysis (ADA) service has been running stably with the huge amount of data. The reliability of the ADA service is high but steadily improving; grid sites are continually validated against a set of standard tests, and a dedicated team of expert shifters provides user support and communicates user problems to the sites. The ATLAS Grid Computing Model is reviewed in this talk. Emphasis is given to ADA system. Description : The ce...

  15. Analysis of Multiple Spurious Operation Scenarios for Decay Heat Removal Function of CANDU Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Youngseung; Bae, Yeon-kyoung; Kim, Myungsu [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    The worst fire broke out in the Browns Ferry Nuclear Power Plant on March 22, 1975. A fire occurrence in a nuclear power plant has recognized a latently serious incident. Nuclear power plants should achieve and maintain the safe shutdown conditions during and after the occurrence of a fire. Functions of the safe shutdown are five such as the shutdown function, the decay heat removal function, the containment function, monitoring and control function, and the supporting function for CANDU type reactors. The purpose of this paper is to analyze that the decay heat removal function of the safe shutdown functions for CANDU type reactors is achieved under the fire induced multiple spurious operation. The scenarios of the fire induced multiple spurious operations (MSO) for the systems used for the decay heat cooling were analyzed. Additionally, Integrated Severe Accident Analysis code for CANDU plants (ISAAC) for determining success criteria of thermal hydraulic analysis was used. Decay heat cooling systems of CANDU reactors are the auxiliary feedwater system, the emergency water supply system, and the shutdown cooling system. A big fire can threat the safety of nuclear power plants, and safe shutdown conditions. The regulatory body in Korea requires the fire hazard analysis including fire induced MSOs. The safe shutdown functions for CANDU reactors are the shutdown function, the decay heat removal function, the containment function, the monitoring and control function, and the supporting service function. The number of spurious operations for the auxiliary feedwater system is more than six and that for the emergency water supply system is one. Additionally, misoperations for the shutdown cooling system are more than two. Accordingly, if total nine components could be spuriously operated, the decay heat removal function would be lost entirely.

  16. Waste Minimization Improvements Achieved Through Six Sigma Analysis Result In Significant Cost Savings

    Energy Technology Data Exchange (ETDEWEB)

    Mousseau, Jeffrey, D.; Jansen, John, R.; Janke, David, H.; Plowman, Catherine, M.

    2003-02-26

    Improved waste minimization practices at the Department of Energy's (DOE) Idaho National Engineering and Environmental Laboratory (INEEL) are leading to a 15% reduction in the generation of hazardous and radioactive waste. Bechtel, BWXT Idaho, LLC (BBWI), the prime management and operations contractor at the INEEL, applied the Six Sigma improvement process to the INEEL Waste Minimization Program to review existing processes and define opportunities for improvement. Our Six Sigma analysis team: composed of an executive champion, process owner, a black belt and yellow belt, and technical and business team members used this statistical based process approach to analyze work processes and produced ten recommendations for improvement. Recommendations ranged from waste generator financial accountability for newly generated waste to enhanced employee recognition programs for waste minimization efforts. These improvements have now been implemented to reduce waste generation rates and are producing positive results.

  17. A functional approach to movement analysis and error identification in sports and physical education

    Directory of Open Access Journals (Sweden)

    Ernst-Joachim eHossner

    2015-09-01

    Full Text Available In a hypothesis-and-theory paper, a functional approach to movement analysis in sports is introduced. In this approach, contrary to classical concepts, it is not anymore the ideal movement of elite athletes that is taken as a template for the movements produced by learners. Instead, movements are understood as the means to solve given tasks that in turn, are defined by to-be-achieved task goals. A functional analysis comprises the steps of (1 recognising constraints that define the functional structure, (2 identifying sub-actions that subserve the achievement of structure-dependent goals, (3 explicating modalities as specifics of the movement execution, and (4 assigning functions to actions, sub-actions and modalities. Regarding motor-control theory, a functional approach can be linked to a dynamical-system framework of behavioural shaping, to cognitive models of modular effect-related motor control as well as to explicit concepts of goal setting and goal achievement. Finally, it is shown that a functional approach is of particular help for sports practice in the context of structuring part practice, recognising functionally equivalent task solutions, finding innovative technique alternatives, distinguishing errors from style, and identifying root causes of movement errors.

  18. A functional approach to movement analysis and error identification in sports and physical education.

    Science.gov (United States)

    Hossner, Ernst-Joachim; Schiebl, Frank; Göhner, Ulrich

    2015-01-01

    In a hypothesis-and-theory paper, a functional approach to movement analysis in sports is introduced. In this approach, contrary to classical concepts, it is not anymore the "ideal" movement of elite athletes that is taken as a template for the movements produced by learners. Instead, movements are understood as the means to solve given tasks that in turn, are defined by to-be-achieved task goals. A functional analysis comprises the steps of (1) recognizing constraints that define the functional structure, (2) identifying sub-actions that subserve the achievement of structure-dependent goals, (3) explicating modalities as specifics of the movement execution, and (4) assigning functions to actions, sub-actions and modalities. Regarding motor-control theory, a functional approach can be linked to a dynamical-system framework of behavioral shaping, to cognitive models of modular effect-related motor control as well as to explicit concepts of goal setting and goal achievement. Finally, it is shown that a functional approach is of particular help for sports practice in the context of structuring part practice, recognizing functionally equivalent task solutions, finding innovative technique alternatives, distinguishing errors from style, and identifying root causes of movement errors.

  19. New Mathematical Functions for Vacuum System Analysis

    Science.gov (United States)

    Woronowicz, Michael S.

    2017-01-01

    A new bivariate function has been found that provides solutions of integrals having the form u (sup minus eta) e (sup u) du which arise when developing predictions for the behavior of pressure within a rigid volume under high vacuum conditions in the presence of venting as well as sources characterized by power law transient decay over the range [0,1] for eta and for u greater than or equal to 0. A few properties of the new function are explored in this work. For instance the eta equals 1/2 case reproduces the Dawson function. In addition, a slight variation of the solution technique reproduces the exponential integral for eta equals 1. The technique used to generate these functions leads to an approach for solving a more general class of nonlinear ordinary differential equations, with the potential for identifying other new functions that solve other integrals.

  20. Gain-of-Function Research: Ethical Analysis.

    Science.gov (United States)

    Selgelid, Michael J

    2016-08-01

    Gain-of-function (GOF) research involves experimentation that aims or is expected to (and/or, perhaps, actually does) increase the transmissibility and/or virulence of pathogens. Such research, when conducted by responsible scientists, usually aims to improve understanding of disease causing agents, their interaction with human hosts, and/or their potential to cause pandemics. The ultimate objective of such research is to better inform public health and preparedness efforts and/or development of medical countermeasures. Despite these important potential benefits, GOF research (GOFR) can pose risks regarding biosecurity and biosafety. In 2014 the administration of US President Barack Obama called for a "pause" on funding (and relevant research with existing US Government funding) of GOF experiments involving influenza, SARS, and MERS viruses in particular. With announcement of this pause, the US Government launched a "deliberative process" regarding risks and benefits of GOFR to inform future funding decisions-and the US National Science Advisory Board for Biosecurity (NSABB) was tasked with making recommendations to the US Government on this matter. As part of this deliberative process the National Institutes of Health commissioned this Ethical Analysis White Paper, requesting that it provide (1) review and summary of ethical literature on GOFR, (2) identification and analysis of existing ethical and decision-making frameworks relevant to (i) the evaluation of risks and benefits of GOFR, (ii) decision-making about the conduct of GOF studies, and (iii) the development of US policy regarding GOFR (especially with respect to funding of GOFR), and (3) development of an ethical and decision-making framework that may be considered by NSABB when analyzing information provided by GOFR risk-benefit assessment, and when crafting its final recommendations (especially regarding policy decisions about funding of GOFR in particular). The ethical and decision-making framework

  1. Achieving minimum caseload requirements: an analysis of hospital quality control reports from 2004-2010.

    Science.gov (United States)

    de Cruppé, Werner; Malik, Marc; Geraedts, Max

    2014-08-18

    Legally mandated minimum hospital caseload requirements for certain invasive procedures, including pancreatectomy, esophagectomy, and some types of organ transplantation, have been in effect in Germany since 2004. The goal of such requirements is to improve patient care by ensuring that patients undergo certain procedures only in hospitals that have met the corresponding minimum caseload requirement. We used the case numbers published in legally mandated hospital quality control reports to determine whether the hospitals actually met the stipulated requirements. We performed a secondary analysis of data supplied by hospitals in their quality control reports for the years 2004, 2006, 2008, and 2010 with respect to six procedures that have a minimum caseload requirement: complex interventions on the esophagus and pancreas, total knee replacement, and hepatic, renal, and stem-cell transplantation. The total case numbers for these six different procedures rose from 22 064 (0.1% of all procedures) in 2004 to 170 801 (0.9% of all procedures) in 2010. From 2006 onward, procedures to which minimum caseload requirements apply have been carried out in half of all hospitals studied. These procedures account for 0.9% of all inpatient cases in Germany. The percentage of hospitals that continue to perform certain procedures despite not having met the minimum caseload requirement ranged from 5% to 45%, depending on the type of procedure, and the percentage of cases carried out in such hospitals ranged from 1% to 15%. These values remained nearly constant for each of the six minimum caseload requirements over the 4 reporting years for which data were examined. The establishment of minimum caseload requirements in Germany in 2004 did not lessen the number of cases performed in violation of these requirements over the period 2004 to 2010.

  2. How the impact of median neuropathy on sensorimotor control capability of hands for diabetes: an achievable assessment from functional perspectives.

    Directory of Open Access Journals (Sweden)

    Haw-Yen Chiu

    Full Text Available To comprehend the sensorimotor control ability in diabetic hands, this study investigated the sensation, motor function and precision pinch performances derived from a pinch-holding-up activity (PHUA test of the hands of diabetic patients and healthy subjects. The precision, sensitivity and specificity of the PHUA test in the measurements of diabetic patients were also analyzed. We hypothesized that the diabetic hands would have impacts on the sensorimotor functions of the hand performances under functionally quantitative measurements. One hundred and fifty-nine patients with clinically defined diabetes mellitus (DM and 95 age- and gender-matched healthy controls were included. Semmes-Weinstein monofilament (SWM, static and moving two-point discrimination (S2PD and M2PD, maximal pinch strength and precision pinch performance tests were conducted to evaluate the sensation, motor and sensorimotor status of the recruited hands. The results showed that there were significant differences (all p<0.05 in SWM, S2PD, M2PD and maximum pinch strength between the DM and control groups. A higher force ratio in the DM patients than in the controls (p<0.001 revealed a poor ability of pinch force adjustment in the DM patients. The percentage of maximal pinch strength was also significantly different (p<0.001 between the DM and control groups. The sensitivity, specificity and area under the receiver operating characteristic curve were 0.85, 0.51, and 0.724, respectively, for the PHUA test. Statistically significant degradations in sensory and motor functions and sensorimotor control ability were observed in the hands of the diabetic patients. The PHUA test could be feasibly used as a clinical tool to determine the sensorimotor function of the hands of diabetic patients from a functional perspective.

  3. Descriptive Topology in Selected Topics of Functional Analysis

    CERN Document Server

    Kakol, J; Pellicer, Manuel Lopez

    2011-01-01

    "Descriptive Topology in Selected Topics of Functional Analysis" is a collection of recent developments in the field of descriptive topology, specifically focused on the classes of infinite-dimensional topological vector spaces that appear in functional analysis. Such spaces include Frechet spaces, (LF)-spaces and their duals, and the space of continuous real-valued functions C(X) on a completely regular Hausdorff space X, to name a few. These vector spaces appear in functional analysis in distribution theory, differential equations, complex analysis, and various other analytical set

  4. Analysis of affinely equivalent Boolean functions

    Institute of Scientific and Technical Information of China (English)

    MENG QingShu; ZHANG HuanGuo; YANG Min; WANG ZhangYi

    2007-01-01

    By some basic transforms and invariant theory, we give two results: 1) an algorithm,which can be used to judge if two Boolean functions are affinely equivalent and to obtain the equivalence relationship if they are equivalent. This is useful in studying Boolean functions and in engineering. For example, we classify all 8-variable homogeneous bent functions of degree 3 into two classes; 2) Reed-Muller codes R(4,6)/R(1,6), R(3,7)/R(1,7) are classified efficiently.

  5. Shape Analysis Using the Auto Diffusion Function

    DEFF Research Database (Denmark)

    Gebal, Katarzyna; Bærentzen, Jakob Andreas; Aanæs, Henrik

    2009-01-01

    Scalar functions defined on manifold triangle meshes is a starting point for many geometry processing algorithms such as mesh parametrization, skeletonization, and segmentation. In this paper, we propose the Auto Diffusion Function (ADF) which is a linear combination of the eigenfunctions......, it is controlled by a single parameter which can be interpreted as feature scale, and, finally, the ADF is invariant to rigid and isometric deformations. We describe the ADF and its properties in detail and compare it to other choices of scalar functions on manifolds. As an example of an application, we present...

  6. Identification of hidden failures in process control systems through function-oriented system analysis

    Energy Technology Data Exchange (ETDEWEB)

    Jalashgar, A.

    1997-05-01

    The main subject of this thesis is to identify hidden failures in process control systems by developing and using a function-oriented system analysis method. Qualitative failure analysis and the characteristics of the classical failure analysis methods and function-oriented modelling methods are covered. The general limitations of the methods in connection with the identification and representation of hidden failures are discussed. The discussion has led to the justification of developing and using a function-oriented system analysis method to identify and represent the capabilities of the system components, which realize different sets of functions in connection with different sets of goals that the system must achieve. A terminology is introduced to define the basic aspects of technical systems including goals, functions, capabilities and physical structure. A function-oriented system analysis method using this terminology and a tailored combination of the two function-oriented modelling approaches, is also introduced. It is then explained how the method can be applied in the identification and representation of hidden failures. The building blocks of a knowledge-oriented system to perform the diagnosis on the basis of the developed method are equally described. A prototype of the knowledge-based system is developed to demonstrate the applicability of the function-oriented system analysis method and the knowledge-based system. The prototype is implemented within the object-oriented software environment G2. (au) 65 ills., 32 refs.

  7. Functional verification coverage measurement and analysis

    CERN Document Server

    Piziali, Andrew

    2007-01-01

    This book addresses a means of quantitatively assessing functional verification progress. Without this process, design and verification engineers, and management, are left guessing whether or not they have completed verifying the device they are designing.

  8. The Relationships among Executive Functions, Metacognitive Skills and Educational Achievement in 5 and 7 Year-Old Children

    Science.gov (United States)

    Bryce, Donna; Whitebread, David; Szucs, Dénes

    2015-01-01

    The relationship between executive functions (inhibitory control and working memory) and metacognitive skills was investigated by applying correlational and regression analyses to data collected from two groups of children. To date, research in this area has lacked a theoretical model for considering these relationships; here we propose and test…

  9. The Relationships among Executive Functions, Metacognitive Skills and Educational Achievement in 5 and 7 Year-Old Children

    Science.gov (United States)

    Bryce, Donna; Whitebread, David; Szucs, Dénes

    2015-01-01

    The relationship between executive functions (inhibitory control and working memory) and metacognitive skills was investigated by applying correlational and regression analyses to data collected from two groups of children. To date, research in this area has lacked a theoretical model for considering these relationships; here we propose and test…

  10. An analysis of functional antagonism and synergism.

    OpenAIRE

    Mackay, D.

    1981-01-01

    1 A method is described for deriving null equations for functional antagonism and synergism. These null equations relate together the concentrations of agonist required to produce equivalent states of a cell or tissue in the presence and in the absence of a functional interactant. 2 In one particular case the null equation leads to conclusions which are very similar to those reached by an earlier author who did not use the null method. However, the null equations give a clearer insight into t...

  11. Safety analysis of autonomous excavator functionality

    Energy Technology Data Exchange (ETDEWEB)

    Seward, D.; Pace, C.; Morrey, R.; Sommerville, I

    2000-10-01

    This paper presents an account of carrying out a hazard analysis to define the safety requirements for an autonomous robotic excavator. The work is also relevant to the growing generic class of heavy automated mobile machinery. An overview of the excavator design is provided and the concept of a safety manager is introduced. The safety manager is an autonomous module responsible for all aspects of system operational safety, and is central to the control system's architecture. Each stage of the hazard analysis is described, i.e. system model creation, hazard definition and hazard analysis. Analysis at an early stage of the design process, and on a system that interfaces directly to an unstructured environment, exposes certain issues relevant to the application of current hazard analysis methods. The approach taken in the analysis is described. Finally, it is explained how the results of the hazard analysis have influenced system design, in particular, safety manager specifications. Conclusions are then drawn about the applicability of hazard analysis of requirements in general, and suggestions are made as to how the approach can be taken further.

  12. Functional Analysis of P4-ATPases

    DEFF Research Database (Denmark)

    Theorin, Lisa

    and mammalian P4-ATPases have been studied extensively and the physiological function is mostly known, while the exact biochemistry and specific activity is mostly unknown. Even though the plant Arabidopsis thaliana has 12 P4-ATPases, not much is known about their function. In this study, the biochemical...... properties, with a focus on the lipid requirements, of the Aminophospholipid ATPase 2 (ALA2), a P4-ATPase from A. thaliana, were characterized. Heterologous expression of ALA2 together with its subunit, the Cdc50 homolog ALA Interacting Subunit 5 (ALIS5), in the yeast Saccharomyces cerevisiae allowed...... is specific for phosphatidylserine and that binding of the lipid to the substrate binding site requires a unique spatial configuration of the lipid head group. Detailed information on the substrate requirements lead the way towards the full function and transport pathway of lipid flippases in plants. Recent...

  13. Asymptotic analysis for functional stochastic differential equations

    CERN Document Server

    Bao, Jianhai; Yuan, Chenggui

    2016-01-01

    This brief treats dynamical systems that involve delays and random disturbances. The study is motivated by a wide variety of systems in real life in which random noise has to be taken into consideration and the effect of delays cannot be ignored. Concentrating on such systems that are described by functional stochastic differential equations, this work focuses on the study of large time behavior, in particular, ergodicity. This brief is written for probabilists, applied mathematicians, engineers, and scientists who need to use delay systems and functional stochastic differential equations in their work. Selected topics from the brief can also be used in a graduate level topics course in probability and stochastic processes.

  14. Stability analysis of impulsive functional differential equations

    CERN Document Server

    Stamova, Ivanka

    2009-01-01

    This book is devoted to impulsive functional differential equations which are a natural generalization of impulsive ordinary differential equations (without delay) and of functional differential equations (without impulses). At the present time the qualitative theory of such equationsis under rapid development. After a presentation of the fundamental theory of existence, uniqueness and continuability of solutions, a systematic development of stability theory for that class of problems is given which makes the book unique. It addresses to a wide audience such as mathematicians, applied research

  15. Functional analysis of anomeric sugar kinases.

    Science.gov (United States)

    Conway, Louis P; Voglmeir, Josef

    2016-09-02

    Anomeric sugar kinases perform fundamental roles in the metabolism of carbohydrates. Under- or overexpression of these enzymes, or mutations causing functional impairments can give rise to diseases such as galactosaemia and so the study of this class of kinase is of critical importance. In addition, anomeric sugar kinases which are naturally promiscuous, or have been artificially made so, may find application in the synthesis of libraries of drug candidates (for example, antibiotics), and natural or unnatural oligosaccharides and glycoconjugates. In this review, we provide an overview of the biological functions of these enzymes, the tools which have been developed to investigate them, and the current frontiers in their study.

  16. [Partial lease squares approach to functional analysis].

    Science.gov (United States)

    Preda, C

    2006-01-01

    We extend the partial least squares (PLS) approach to functional data represented in our models by sample paths of stochastic process with continuous time. Due to the infinite dimension, when functional data are used as a predictor for linear regression and classification models, the estimation problem is an ill-posed one. In this context, PLS offers a simple and efficient alternative to the methods based on the principal components of the stochastic process. We compare the results given by the PLS approach and other linear models using several datasets from economy, industry and medical fields.

  17. Genetic analysis of basophil function in vivo.

    Science.gov (United States)

    Sullivan, Brandon M; Liang, Hong-Erh; Bando, Jennifer K; Wu, Davina; Cheng, Laurence E; McKerrow, James K; Allen, Christopher D C; Locksley, Richard M

    2011-06-01

    Contributions by basophils to allergic and helminth immunity remain incompletely defined. Using sensitive interleukin 4 (Il4) reporter alleles, we demonstrate here that basophil IL-4 production occurs by a CD4(+) T cell-dependent process restricted to the peripheral tissues affected. We genetically marked and achieved specific deletion of basophils and found that basophils did not mediate T helper type 2 (T(H)2) priming in vivo. Two-photon imaging confirmed that basophils did not interact with antigen-specific T cells in lymph nodes but engaged in prolonged serial interactions with T cells in lung tissues. Although targeted deletion of IL-4 and IL-13 in either CD4(+) T cells or basophils had a minimal effect on worm clearance, deletion from both lineages demonstrated a nonredundant role for basophil cytokines in primary helminth immunity.

  18. Analysis of radial basis function interpolation approach

    Institute of Scientific and Technical Information of China (English)

    Zou You-Long; Hu Fa-Long; Zhou Can-Can; Li Chao-Liu; Dunn Keh-Jim

    2013-01-01

    The radial basis function (RBF) interpolation approach proposed by Freedman is used to solve inverse problems encountered in well-logging and other petrophysical issues. The approach is to predict petrophysical properties in the laboratory on the basis of physical rock datasets, which include the formation factor, viscosity, permeability, and molecular composition. However, this approach does not consider the effect of spatial distribution of the calibration data on the interpolation result. This study proposes a new RBF interpolation approach based on the Freedman's RBF interpolation approach, by which the unit basis functions are uniformly populated in the space domain. The inverse results of the two approaches are comparatively analyzed by using our datasets. We determine that although the interpolation effects of the two approaches are equivalent, the new approach is more flexible and beneficial for reducing the number of basis functions when the database is large, resulting in simplification of the interpolation function expression. However, the predicted results of the central data are not sufficiently satisfied when the data clusters are far apart.

  19. Binocular Vision Function Analysis of 75 Subjects

    Institute of Scientific and Technical Information of China (English)

    Ya-ping Gao; Hai-ying Wang; Xiu-rong Tang; Ying Zhang; Xiao-tong Huo

    2004-01-01

    @@ We randomly chose 75 subjects; 34 men and 41 womenwith an average age of 21 years. Our study method included subject interviews, and evamuination of their refractive and binocular vision functions.We recorded, basic biographical data, medical history, family history, lifestyle factors that relate to their use of vision and history of wearing glasses.

  20. Differential analysis of matrix convex functions

    DEFF Research Database (Denmark)

    Hansen, Frank; Tomiyama, Jun

    2007-01-01

    We analyze matrix convex functions of a fixed order defined in a real interval by differential methods as opposed to the characterization in terms of divided differences given by Kraus [F. Kraus, Über konvekse Matrixfunktionen, Math. Z. 41 (1936) 18-42]. We obtain for each order conditions for ma...

  1. Density functional and neural network analysis

    DEFF Research Database (Denmark)

    Jalkanen, K. J.; Bohr, Henrik

    1997-01-01

    Density functional theory (DFT) calculations have been carried out for hydrated L-alanine, L-alanyl-L-alanine and N-acetyl L-alanine N'-methylamide and examined with respect to the effect of water on the structure, the vibrational frequencies, vibrational absorption (VA) and vibrational circular...

  2. Analysis of the Bogoliubov free energy functional

    DEFF Research Database (Denmark)

    Reuvers, Robin

    In this thesis, we analyse a variational reformulation of the Bogoliubov approximation that is used to describe weakly-interacting translationally-invariant Bose gases. For the resulting model, the `Bogoliubov free energy functional', we demonstrate existence of minimizers as well as the presence...

  3. Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases Quantitative analysis of strategies to achieve the 2020 goals for neglected tropical diseases: Where are we now?

    NARCIS (Netherlands)

    T.D. Hollingsworth (T. Déirdre); E.R. Adams (Emily R.); R.M. Anderson (Roy M.); K. Atkins (Katherine); S. Bartsch (Sarah); M-G. Basáñez (María-Gloria); M. Behrend (Matthew); D.J. Blok (David); L.A.C. Chapman (Lloyd A. C.); L.E. Coffeng (Luc); O. Courtenay (Orin); R.E. Crump (Ron E.); S.J. de Vlas (Sake); A.P. Dobson (Andrew); L. Dyson (Louise); H. Farkas (Hajnal); A.P. Galvani (Alison P.); M. Gambhir (Manoj); D. Gurarie (David); M.A. Irvine (Michael A.); S. Jervis (Sarah); M.J. Keeling (Matt J.); L. Kelly-Hope (Louise); C. King (Charles); B.Y. Lee (Bruce Y.); E.A. le Rutte (Epke A.); T.M. Lietman (Thomas M.); M. Ndeffo-Mbah (Martial); G.F. Medley (Graham F.); E. Michael (Edwin); A. Pandey (Abhishek); J.K. Peterson (Jennifer K.); A. Pinsent (Amy); T.C. Porco (Travis C.); J.H. Richardus (Jan Hendrik); L. Reimer (Lisa); K.S. Rock (Kat S.); B.K. Singh (Brajendra K.); W.A. Stolk (Wilma); S. Swaminathan (Subramanian); S.J. Torr (Steve J.); J. Townsend (Jeffrey); J. Truscott (James); M. Walker (Martin); A. Zoueva (Alexandra)

    2015-01-01

    textabstractQuantitative analysis and mathematical models are useful tools in informing strategies to control or eliminate disease. Currently, there is an urgent need to develop these tools to inform policy to achieve the 2020 goals for neglected tropical diseases (NTDs). In this paper we give an ov

  4. Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases Quantitative analysis of strategies to achieve the 2020 goals for neglected tropical diseases: Where are we now?

    NARCIS (Netherlands)

    T.D. Hollingsworth (T. Déirdre); E.R. Adams (Emily R.); R.M. Anderson (Roy M.); K. Atkins (Katherine); S. Bartsch (Sarah); M-G. Basáñez (María-Gloria); M. Behrend (Matthew); D.J. Blok (David); L.A.C. Chapman (Lloyd A. C.); L.E. Coffeng (Luc); O. Courtenay (Orin); R.E. Crump (Ron E.); S.J. de Vlas (Sake); A.P. Dobson (Andrew); L. Dyson (Louise); H. Farkas (Hajnal); A.P. Galvani (Alison P.); M. Gambhir (Manoj); D. Gurarie (David); M.A. Irvine (Michael A.); S. Jervis (Sarah); M.J. Keeling (Matt J.); L. Kelly-Hope (Louise); C. King (Charles); B.Y. Lee (Bruce Y.); E.A. le Rutte (Epke); T.M. Lietman (Thomas M.); M. Ndeffo-Mbah (Martial); G.F. Medley (Graham F.); E. Michael (Edwin); A. Pandey (Abhishek); J.K. Peterson (Jennifer K.); A. Pinsent (Amy); T.C. Porco (Travis C.); J.H. Richardus (Jan Hendrik); L. Reimer (Lisa); K.S. Rock (Kat S.); B.K. Singh (Brajendra K.); W.A. Stolk (Wilma); S. Swaminathan (Subramanian); S.J. Torr (Steve J.); J. Townsend (Jeffrey); J. Truscott (James); M. Walker (Martin); A. Zoueva (Alexandra)

    2015-01-01

    textabstractQuantitative analysis and mathematical models are useful tools in informing strategies to control or eliminate disease. Currently, there is an urgent need to develop these tools to inform policy to achieve the 2020 goals for neglected tropical diseases (NTDs). In this paper we give an ov

  5. The Analysis of Nida’s Functional Equivalence Theory

    Institute of Scientific and Technical Information of China (English)

    杨雪; 任培红

    2014-01-01

    Eugene A. Nida is an influential translation theoretician with great research achievements. The functional equivalence theory which is the core of his translation theories lays a solid foundation for the modern translation. However, there also exist some limitations in it. It should be dialectically analyzed to find its contributions and limitations.

  6. Continuous nowhere differentiable functions the monsters of analysis

    CERN Document Server

    Jarnicki, Marek

    2015-01-01

    This book covers the construction, analysis, and theory of continuous nowhere differentiable functions, comprehensively and accessibly. After illuminating the significance of the subject through an overview of its history, the reader is introduced to the sophisticated toolkit of ideas and tricks used to study the explicit continuous nowhere differentiable functions of Weierstrass, Takagi–van der Waerden, Bolzano, and others. Modern tools of functional analysis, measure theory, and Fourier analysis are applied to examine the generic nature of continuous nowhere differentiable functions, as well as linear structures within the (nonlinear) space of continuous nowhere differentiable functions. To round out the presentation, advanced techniques from several areas of mathematics are brought together to give a state-of-the-art analysis of Riemann’s continuous, and purportedly nowhere differentiable, function. For the reader’s benefit, claims requiring elaboration, and open problems, are clearly indicated. An a...

  7. The power of multiplexed functional analysis of genetic variants.

    Science.gov (United States)

    Gasperini, Molly; Starita, Lea; Shendure, Jay

    2016-10-01

    New technologies have recently enabled saturation mutagenesis and functional analysis of nearly all possible variants of regulatory elements or proteins of interest in single experiments. Here we discuss the past, present, and future of such multiplexed (functional) assays for variant effects (MAVEs). MAVEs provide detailed insight into sequence-function relationships, and they may prove critical for the prospective clinical interpretation of genetic variants.

  8. Classwide Functional Analysis and Treatment of Preschoolers' Disruptive Behavior

    Science.gov (United States)

    Poole, Veena Y.; Dufrene, Brad A.; Sterling, Heather E.; Tingstrom, Daniel H.; Hardy, Christina M.

    2012-01-01

    Relatively few functional assessment and intervention studies have been conducted in preschool classrooms with children of typical development who engage in high incidence problem behaviors. Moreover, limited studies have used functional assessment procedures with the class as the unit of analysis. This study included functional analyses and a…

  9. Functional Foods Baseline and Requirements Analysis

    Science.gov (United States)

    Cooper, M. R.; Bermudez-Aguirre, L. D.; Douglas, G.

    2015-01-01

    Current spaceflight foods were evaluated to determine if their nutrient profile supports positioning as a functional food and if the stability of the bioactive compound within the food matrix over an extended shelf-life correlated with the expected storage duration during the mission. Specifically, the research aims were: Aim A. To determine the amount of each nutrient in representative spaceflight foods immediately after processing and at predetermined storage time to establish the current nutritional state. Aim B. To identify the requirements to develop foods that stabilize these nutrients such that required concentrations are maintained in the space food system throughout long duration missions (up to five years). Aim C. To coordinate collaborations with health and performance groups that may require functional foods as a countermeasure.

  10. Functional Analysis of P4-ATPases

    DEFF Research Database (Denmark)

    Theorin, Lisa

    studies have identified P4-ATPases as phospholipid transporters that interact and cooperate with cytosolic coat proteins to drive vesicle formation at the trans-Golgi network, endosome compartment and plasma membrane. Our hypothesis is that by flipping a lipid the P4-ATPases either provide essential......Across membranes of the late secretory pathway in eukaryotic cells an asymmetric lipid distribution is maintained, with the lipids phosphatidylserine and phosphatidylethanolamine restricted to the cytoplasmic leaflet of the membrane. In recent years a subgroup of P-type ATPases, P4-ATPases, has...... and mammalian P4-ATPases have been studied extensively and the physiological function is mostly known, while the exact biochemistry and specific activity is mostly unknown. Even though the plant Arabidopsis thaliana has 12 P4-ATPases, not much is known about their function. In this study, the biochemical...

  11. Truncated Moment Analysis of Nucleon Structure Functions

    Energy Technology Data Exchange (ETDEWEB)

    A. Psaker; W. Melnitchouk; M. E. Christy; C. E. Keppel

    2007-11-16

    We employ a novel new approach using "truncated" moments, or integrals of structure functions over restricted regions of x, to study local quark-hadron duality, and the degree to which individual resonance regions are dominated by leading twists. Because truncated moments obey the same Q^2 evolution equations as the leading twist parton distributions, this approach makes possible for the first time a description of resonance region data and the phenomenon of quark-hadron duality directly from QCD.

  12. Functional analysis of the Fusarium graminearum phosphatome.

    Science.gov (United States)

    Yun, Yingzi; Liu, Zunyong; Yin, Yanni; Jiang, Jinhua; Chen, Yun; Xu, Jin-Rong; Ma, Zhonghua

    2015-07-01

    Phosphatases are known to play important roles in the regulation of various cellular processes in eukaryotes. However, systematic characterization of the phosphatome has not been reported in phytopathogenic fungi. The wheat scab fungus Fusarium graminearum contains 82 putative phosphatases. The biological functions of each phosphatase were investigated in this study. Although 11 phosphatase genes appeared to be essential, deletion mutants of the other 71 phosphatase genes were obtained and characterized for changes in 15 phenotypes, including vegetative growth, nutrient response and virulence. Overall, the deletion of 63 phosphatase genes resulted in changes in at least one of the phenotypes assayed. Interestingly, the deletion of four genes (Fg06297, Fg03333, Fg03826 and Fg07932) did not dramatically affect hyphal growth, but led to strongly reduced virulence. Western blot analyses showed that three phosphatases (Fg10516, Fg03333 and Fg12867) functioned as negative regulators of the mitogen-activated protein kinase signaling pathways. In addition, we found, for the first time, that FgCdc14 is dispensable for growth, but plays an important role in ribosome biogenesis. Overall, in this first functional characterization of the fungal phosphatome, phosphatases important for various aspects of hyphal growth, development, plant infection and secondary metabolism were identified in the phytopathogenic fungus F. graminearum.

  13. ANALYSIS TO NEYMAN-PEARSON CLASSIFICATION WITH CONVEX LOSS FUNCTION

    Institute of Scientific and Technical Information of China (English)

    Min Han; Dirong Chen; Zhaoxu Sun

    2008-01-01

    Neyman-Pearson classification has been studied in several articles before.But they all proceeded in the classes of indicator functions with indicator function as the loss function,which make the calculation to be difficult.This paper investigates NeymanPearson classification with convex loss function in the arbitrary class of real measurable functions.A general condition is given under which Neyman-Pearson classification with convex loss function has the same classifier as that with indicator loss function.We give analysis to NP-ERM with convex loss function and prove it's performance guarantees.An example of complexity penalty pair about convex loss function risk in terms of Rademacher averages is studied,which produces a tight PAC bound of the NP-ERM with convex loss function.

  14. Photonic encryption : modeling and functional analysis of all optical logic.

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Jason D.; Schroeppel, Richard Crabtree; Robertson, Perry J.

    2004-10-01

    With the build-out of large transport networks utilizing optical technologies, more and more capacity is being made available. Innovations in Dense Wave Division Multiplexing (DWDM) and the elimination of optical-electrical-optical conversions have brought on advances in communication speeds as we move into 10 Gigabit Ethernet and above. Of course, there is a need to encrypt data on these optical links as the data traverses public and private network backbones. Unfortunately, as the communications infrastructure becomes increasingly optical, advances in encryption (done electronically) have failed to keep up. This project examines the use of optical logic for implementing encryption in the photonic domain to achieve the requisite encryption rates. This paper documents the innovations and advances of work first detailed in 'Photonic Encryption using All Optical Logic,' [1]. A discussion of underlying concepts can be found in SAND2003-4474. In order to realize photonic encryption designs, technology developed for electrical logic circuits must be translated to the photonic regime. This paper examines S-SEED devices and how discrete logic elements can be interconnected and cascaded to form an optical circuit. Because there is no known software that can model these devices at a circuit level, the functionality of S-SEED devices in an optical circuit was modeled in PSpice. PSpice allows modeling of the macro characteristics of the devices in context of a logic element as opposed to device level computational modeling. By representing light intensity as voltage, 'black box' models are generated that accurately represent the intensity response and logic levels in both technologies. By modeling the behavior at the systems level, one can incorporate systems design tools and a simulation environment to aid in the overall functional design. Each black box model takes certain parameters (reflectance, intensity, input response), and models the optical ripple

  15. Analysis of the Bogoliubov free energy functional

    DEFF Research Database (Denmark)

    Reuvers, Robin

    In this thesis, we analyse a variational reformulation of the Bogoliubov approximation that is used to describe weakly-interacting translationally-invariant Bose gases. For the resulting model, the `Bogoliubov free energy functional', we demonstrate existence of minimizers as well as the presence...... of a phase transition to Bose{Einstein condensation, and establish the phase diagram. We also give a calculation of the critical temperature assuming the gas is dilute, and nd that it agrees with earlier numerical studies. The thesis contains an introduction, a physical review paper outlining the main...

  16. Density functional and neural network analysis

    DEFF Research Database (Denmark)

    Jalkanen, K. J.; Bohr, Henrik

    1997-01-01

    Density functional theory (DFT) calculations have been carried out for hydrated L-alanine, L-alanyl-L-alanine and N-acetyl L-alanine N'-methylamide and examined with respect to the effect of water on the structure, the vibrational frequencies, vibrational absorption (VA) and vibrational circular...... dichroism (VCD) intensities. The large changes due to hydration on the structures, relative stability of conformers, and in the VA and VCD spectra observed experimentally are reproduced by the DFT calculations. Furthermore a neural network was constructed for reproducing the inverse scattering data (infer...

  17. Functional Analysis for Double Shell Tank (DST) Subsystems

    Energy Technology Data Exchange (ETDEWEB)

    SMITH, D.F.

    2000-08-22

    This functional analysis identifies the hierarchy and describes the subsystem functions that support the Double-Shell Tank (DST) System described in HNF-SD-WM-TRD-007, System Specification for the Double-Shell Tank System. Because of the uncertainty associated with the need for upgrades of the existing catch tanks supporting the Waste Feed Delivery (WFD) mission, catch tank functions are not addressed in this document. The functions identified herein are applicable to the Phase 1 WFD mission only.

  18. Spatial Analysis of the National Evaluation of Scholastic Achievement (ENLACE in Schools of the Municipality of Juarez, Chihuahua

    Directory of Open Access Journals (Sweden)

    Luis Ernesto Cervera Gómez

    2008-05-01

    Full Text Available This research was focused on analyzing the results of the first National Assessment of Academic Achievement for Scholar Centers (ENLACE; acronym in Spanish applied during the year 2006 in the Municipality of Juarez (State of Chihuahua, Mexico. In order to conduct the spatial analysis a geographical information system (GIS was used to make a georeferenced database were all variables were connected to a point representing a school. Results of the examinations expressed as deficient, elemental, good en excellent were spatially distributed over the urban area of Ciudad Juárez. Apparently there is a high spatial correlation between ENLACE’s results with the socioeconomic level of people. In this way results going from good to excellent were spatially located over the sectors more developed of the city. Poor results going from Insufficient to Elemental were spatially located at places with higher deficits of infrastructure and low socioeconomic levels.

  19. Research on the psychological gap, personality and achievement of in-school youth based on regression analysis

    Directory of Open Access Journals (Sweden)

    Lei Zhou

    2017-02-01

    Full Text Available Although our society is in rapid development, the psychological problems among in-school university students are increasingly obvious. According to this problem, this thesis applied the Psychological Gap Scale made by Caixia Ma with EPQ and AMS, and made random questionnaire survey among 400 students in a comprehensive university. The survey found out that the average scores of all psychological gap dimensions exceeded the critical value 3, showing most students in that university have psychological gap. Their personality stability, introversion and extroversion are all above the national norm level while their stubbornness is lower than it. Besides, the students’ motivation in pursuing success is stronger than their motivation in avoiding failure. In the last part, this thesis reached the conclusion that personality leaves a great impact in the students’ psychology through regression analysis model and study of the quantitative relations among personality, achievement and psychological gap.

  20. Functional analysis of fungal polyketide biosynthesis genes.

    Science.gov (United States)

    Fujii, Isao

    2010-05-01

    Fungal polyketides have huge structural diversity from simple aromatics to highly modified complex reduced-type compounds. Despite such diversty, single modular iterative type I polyketide synthases (iPKSs) are responsible for their carbon skeleton construction. Using heterologous expression systems, we have studied on ATX, a 6-methylsalicylic acid synthase from Aspergillus terreus as a model iPKS. In addition, iPKS functions involved in fungal spore pigment biosynthesis were analyzed together with polyketide-shortening enzymes that convert products of PKSs to shorter ketides by hydrolytic C-C bond cleavage. In our studies on reducing-type iPKSs, we cloned and expressed PKS genes, pksN, pksF, pksK and sol1 from Alternaria solani. The sol gene cluster was found to be involved in solanapyrone biosynthesis and sol5 was identified to encode solanapyrone synthase, a Diels-Alder enzyme. Our fungal PKS studies were further extended to identify the function of PKS-nonribosomal peptide synthase involved in cyclopiazonic acid biosynthesis.

  1. Identification and Analysis of Labor Productivity Components Based on ACHIEVE Model (Case Study: Staff of Kermanshah University of Medical Sciences)

    Science.gov (United States)

    Ziapour, Arash; Khatony, Alireza; Kianipour, Neda; Jafary, Faranak

    2015-01-01

    Identification and analysis of the components of labor productivity based on ACHIEVE model was performed among employees in different parts of Kermanshah University of Medical Sciences in 2014. This was a descriptive correlational study in which the population consisted of 270 working personnel in different administrative groups (contractual, fixed- term and regular) at Kermanshah University of Medical Sciences (872 people) that were selected among 872 people through stratified random sampling method based on Krejcie and Morgan sampling table. The survey tool included labor productivity questionnaire of ACHIEVE. Questionnaires were confirmed in terms of content and face validity, and their reliability was calculated using Cronbach’s alpha coefficient. The data were analyzed by SPSS-18 software using descriptive and inferential statistics. The mean scores for labor productivity dimensions of the employees, including environment (environmental fit), evaluation (training and performance feedback), validity (valid and legal exercise of personnel), incentive (motivation or desire), help (organizational support), clarity (role perception or understanding), ability (knowledge and skills) variables and total labor productivity were 4.10±0.630, 3.99±0.568, 3.97±0.607, 3.76±0.701, 3.63±0.746, 3.59±0.777, 3.49±0.882 and 26.54±4.347, respectively. Also, the results indicated that the seven factors of environment, performance assessment, validity, motivation, organizational support, clarity, and ability were effective in increasing labor productivity. The analysis of the current status of university staff in the employees’ viewpoint suggested that the two factors of environment and evaluation, which had the greatest impact on labor productivity in the viewpoint of the staff, were in a favorable condition and needed to be further taken into consideration by authorities. PMID:25560364

  2. GOMA: functional enrichment analysis tool based on GO modules

    Institute of Scientific and Technical Information of China (English)

    Qiang Huang; Ling-Yun Wu; Yong Wang; Xiang-Sun Zhang

    2013-01-01

    Analyzing the function of gene sets is a critical step in interpreting the results of high-throughput experiments in systems biology.A variety of enrichment analysis tools have been developed in recent years,but most output a long list of significantly enriched terms that are often redundant,making it difficult to extract the most meaningful functions.In this paper,we present GOMA,a novel enrichment analysis method based on the new concept of enriched functional Gene Ontology (GO) modules.With this method,we systematically revealed functional GO modules,i.e.,groups of functionally similar GO terms,via an optimization model and then ranked them by enrichment scores.Our new method simplifies enrichment analysis results by reducing redundancy,thereby preventing inconsistent enrichment results among functionally similar terms and providing more biologically meaningful results.

  3. GOMA: functional enrichment analysis tool based on GO modules

    Science.gov (United States)

    Huang, Qiang; Wu, Ling-Yun; Wang, Yong; Zhang, Xiang-Sun

    2013-01-01

    Analyzing the function of gene sets is a critical step in interpreting the results of high-throughput experiments in systems biology. A variety of enrichment analysis tools have been developed in recent years, but most output a long list of significantly enriched terms that are often redundant, making it difficult to extract the most meaningful functions. In this paper, we present GOMA, a novel enrichment analysis method based on the new concept of enriched functional Gene Ontology (GO) modules. With this method, we systematically revealed functional GO modules, i.e., groups of functionally similar GO terms, via an optimization model and then ranked them by enrichment scores. Our new method simplifies enrichment analysis results by reducing redundancy, thereby preventing inconsistent enrichment results among functionally similar terms and providing more biologically meaningful results. PMID:23237213

  4. Noninvasive analysis of human neck muscle function

    Science.gov (United States)

    Conley, M. S.; Meyer, R. A.; Bloomberg, J. J.; Feeback, D. L.; Dudley, G. A.

    1995-01-01

    STUDY DESIGN. Muscle use evoked by exercise was determined by quantifying shifts in signal relaxation times of T2-weighted magnetic resonance images. Images were collected at rest and after exercise at each of two intensities (moderate and intense) for each of four head movements: 1) extension, 2) flexion, 3) rotation, and 4) lateral flexion. OBJECTIVE. This study examined the intensity and pattern of neck muscle use evoked by various movements of the head. The results will help elucidate the pathophysiology, and thus methods for treating disorders of the cervical musculoskeletal system. SUMMARY OF BACKGROUND DATA. Exercise-induced contrast shifts in T2 has been shown to indicate muscle use during the activity. The noninvasive nature of magnetic resonance imaging appears to make it an ideal approach for studying the function of the complex neuromuscular system of the neck. METHODS. The extent of T2 increase was examined to gauge how intensely nine different neck muscles or muscle pairs were used in seven subjects. The absolute and relative cross-sectional area of muscle showing a shift in signal relaxation was assessed to infer the pattern of use among and within individual neck muscles or muscle pairs. RESULTS. Signal relaxation increased with exercise intensity for each head movement. The absolute and relative cross-sectional area of muscle showing a shift in signal relaxation also increased with exercise load. Neck muscles or muscle pairs extensively used to perform each head movement were: extension--semispinalis capitis and cervicis and splenius capitis; flexion--sternocleidomastoid and longus capitis and colli; rotation--splenius capitis, levator scapulae, scalenus, semispinalis capitis ipsilateral to the rotation, and sternocleidomastoid contralateral; and lateral flexion--sternocleidomastoid CONCLUSION. The results of this study, in part, agree with the purported functions of neck muscles derived from anatomic location. This also was true for the few

  5. 使用华为交换机实现简单路由功能%Using Huawei Switch to Achieve a Simple Routing Function

    Institute of Scientific and Technical Information of China (English)

    梁泉

    2011-01-01

    To save costs, the company whose network scale is not large, can be achieved by using Huawei switches to achieve a simple routing function, save the high cost of purchasing router. At the same time, makes backup for the network settings, and allows the system when in the partial failure, can automatically switch to the normal working state.%为节约成本,对网络规模不是很大的公司,可以通过华为交换机实现简单路由功能,节省购买路由器的高额成本。同时,对网络进行备份设置,使系统在出现局部故障时。能自动切换到正常工作状态。

  6. Function analysis for waste information systems

    Energy Technology Data Exchange (ETDEWEB)

    Sexton, J.L.; Neal, C.T.; Heath, T.C.; Starling, C.D.

    1996-04-01

    This study has a two-fold purpose. It seeks to identify the functional requirements of a waste tracking information system and to find feasible alternatives for meeting those requirements on the Oak Ridge Reservation (ORR) and the Portsmouth (PORTS) and Paducah (PGDP) facilities; identify options that offer potential cost savings to the US government and also show opportunities for improved efficiency and effectiveness in managing waste information; and, finally, to recommend a practical course of action that can be immediately initiated. In addition to identifying relevant requirements, it also identifies any existing requirements that are currently not being completely met. Another aim of this study is to carry out preliminary benchmarking by contacting representative companies about their strategic directions in waste information. The information obtained from representatives of these organizations is contained in an appendix to the document; a full benchmarking effort, however, is beyond the intended scope of this study.

  7. Static Analysis of Functionally Graded Composite Beams

    Science.gov (United States)

    Das, S.; Sarangi, S. K.

    2016-09-01

    This paper presents a study of functionally graded (FG) composite beam. The FG material for the beam is considered to be composed of different layers of homogeneous material. The fiber volume fraction corresponding to each layer is calculated by considering its variation along the thickness direction (z) according to a power law. Accordingly, the effective properties of the homogeneous layers are estimated and a beam composed of this FG material is modelled using the commercially available ANSYS software. The solid 186 layered structural solid element has been used for discretization of the model of the FG beam. The model developed is validated by comparing the results with those numerical results available in literature. Results are presented for simply supported and fixed boundary conditions for the FG beam. The stress distribution across the thickness of the FG composite beam has also been analyzed.

  8. Effects of a free school breakfast programme on school attendance, achievement, psychosocial function, and nutrition: a stepped wedge cluster randomised trial

    Directory of Open Access Journals (Sweden)

    Maddison Ralph

    2010-11-01

    Full Text Available Abstract Background Approximately 55,000 children in New Zealand do not eat breakfast on any given day. Regular breakfast skipping has been associated with poor diets, higher body mass index, and adverse effects on children's behaviour and academic performance. Research suggests that regular breakfast consumption can improve academic performance, nutrition and behaviour. This paper describes the protocol for a stepped wedge cluster randomised trial of a free school breakfast programme. The aim of the trial is to determine the effects of the breakfast intervention on school attendance, achievement, psychosocial function, dietary habits and food security. Methods/Design Sixteen primary schools in the North Island of New Zealand will be randomised in a sequential stepped wedge design to a free before-school breakfast programme consisting of non-sugar coated breakfast cereal, milk products, and/or toast and spreads. Four hundred children aged 5-13 years (approximately 25 per school will be recruited. Data collection will be undertaken once each school term over the 2010 school year (February to December. The primary trial outcome is school attendance, defined as the proportion of students achieving an attendance rate of 95% or higher. Secondary outcomes are academic achievement (literacy, numeracy, self-reported grades, sense of belonging at school, psychosocial function, dietary habits, and food security. A concurrent process evaluation seeks information on parents', schools' and providers' perspectives of the breakfast programme. Discussion This randomised controlled trial will provide robust evidence of the effects of a school breakfast programme on students' attendance, achievement and nutrition. Furthermore the study provides an excellent example of the feasibility and value of the stepped wedge trial design in evaluating pragmatic public health intervention programmes. Trial Registration Number Australian New Zealand Clinical Trials Registry

  9. Effects of a free school breakfast programme on school attendance, achievement, psychosocial function, and nutrition: a stepped wedge cluster randomised trial.

    Science.gov (United States)

    Ni Mhurchu, Cliona; Turley, Maria; Gorton, Delvina; Jiang, Yannan; Michie, Jo; Maddison, Ralph; Hattie, John

    2010-11-29

    Approximately 55,000 children in New Zealand do not eat breakfast on any given day. Regular breakfast skipping has been associated with poor diets, higher body mass index, and adverse effects on children's behaviour and academic performance. Research suggests that regular breakfast consumption can improve academic performance, nutrition and behaviour. This paper describes the protocol for a stepped wedge cluster randomised trial of a free school breakfast programme. The aim of the trial is to determine the effects of the breakfast intervention on school attendance, achievement, psychosocial function, dietary habits and food security. Sixteen primary schools in the North Island of New Zealand will be randomised in a sequential stepped wedge design to a free before-school breakfast programme consisting of non-sugar coated breakfast cereal, milk products, and/or toast and spreads. Four hundred children aged 5-13 years (approximately 25 per school) will be recruited. Data collection will be undertaken once each school term over the 2010 school year (February to December). The primary trial outcome is school attendance, defined as the proportion of students achieving an attendance rate of 95% or higher. Secondary outcomes are academic achievement (literacy, numeracy, self-reported grades), sense of belonging at school, psychosocial function, dietary habits, and food security. A concurrent process evaluation seeks information on parents', schools' and providers' perspectives of the breakfast programme. This randomised controlled trial will provide robust evidence of the effects of a school breakfast programme on students' attendance, achievement and nutrition. Furthermore the study provides an excellent example of the feasibility and value of the stepped wedge trial design in evaluating pragmatic public health intervention programmes. Australian New Zealand Clinical Trials Registry (ANZCTR) - ACTRN12609000854235.

  10. A Meta-Analytic Path Analysis of the Internal/External Frame of Reference Model of Academic Achievement and Academic Self-Concept

    Science.gov (United States)

    Moller, Jens; Pohlmann, Britta; Koller, Olaf; Marsh, Herb W.

    2009-01-01

    A meta-analysis of 69 data sets ( N = 125,308) was carried out on studies that simultaneously evaluate the effects of math and verbal achievements on math and verbal self-concepts. As predicted by the internal/external frame of reference (I/E) model, math and verbal achievements were highly correlated overall (0.67), but the correlation between…

  11. Rumen development process in goats as affected by supplemental feeding v. grazing: age-related anatomic development, functional achievement and microbial colonisation.

    Science.gov (United States)

    Jiao, Jinzhen; Li, Xiaopeng; Beauchemin, Karen A; Tan, Zhiliang; Tang, Shaoxun; Zhou, Chuanshe

    2015-03-28

    The aim of the present study was to describe age-related changes in anatomic, functional and microbial variables during the rumen development process, as affected by the feeding system (supplemental feeding v. grazing), in goats. Goats were slaughtered at seven time points that were selected to reflect the non-rumination (0, 7 and 14 d), transition (28 and 42 d) and rumination (56 and 70 d) phases of rumen development. Total volatile fatty acid (TVFA) concentration (P= 0·002), liquid-associated bacterial and archaeal copy numbers (Pmicrobial copy numbers (Pmicrobial copy numbers increased (Pamylase and protease activity potentials occurred at 28 d. Most anatomic and functional variables evolved progressively from 14 to 42 d, while microbial colonisation was fastest from birth to 28 d. These outcomes suggest that the supplemental feeding system is more effective in promoting rumen development than the grazing system; in addition, for both the feeding systems, microbial colonisation in the rumen is achieved at 1 month, functional achievement at 2 months, and anatomic development after 2 months.

  12. Model-free functional MRI analysis for detecting low-frequency functional connectivity in the human brain

    Science.gov (United States)

    Wismueller, Axel; Lange, Oliver; Auer, Dorothee; Leinsinger, Gerda

    2010-03-01

    Slowly varying temporally correlated activity fluctuations between functionally related brain areas have been identified by functional magnetic resonance imaging (fMRI) research in recent years. These low-frequency oscillations of less than 0.08 Hz appear to play a major role in various dynamic functional brain networks, such as the so-called 'default mode' network. They also have been observed as a property of symmetric cortices, and they are known to be present in the motor cortex among others. These low-frequency data are difficult to detect and quantify in fMRI. Traditionally, user-based regions of interests (ROI) or 'seed clusters' have been the primary analysis method. In this paper, we propose unsupervised clustering algorithms based on various distance measures to detect functional connectivity in resting state fMRI. The achieved results are evaluated quantitatively for different distance measures. The Euclidian metric implemented by standard unsupervised clustering approaches is compared with a non-metric topographic mapping of proximities based on the the mutual prediction error between pixel-specific signal dynamics time-series. It is shown that functional connectivity in the motor cortex of the human brain can be detected based on such model-free analysis methods for resting state fMRI.

  13. Functional endoscopic analysis of beatbox performers.

    Science.gov (United States)

    Sapthavee, Andrew; Yi, Paul; Sims, H Steven

    2014-05-01

    Beatboxing is a form of vocal percussion in which performers imitate drum sounds, interspersed with vocalization and other sounds, using their vocal tracts. Although similarities between beatboxing and singing are expected because of the anatomy involved, the medical literature has a wealth of information on singing and minimal studies on beatboxing. The objective of our study was to report on a case series of functional endoscopic evaluation of the anatomy involved in beatboxing and determine whether beatboxing may be a risk factor for phonotrauma or if this form of vocalization might be protective of the vocal folds. We reviewed the flexible fiberoptic data collected from four beatbox artists who were evaluated at an outpatient Laryngology clinic. These records included videos of a standard flexible laryngoscopic evaluation during which the beatboxers performed beatbox sounds in isolation and in various combinations ("beats"), both standardized and improvised. All four participants were males aged 22-32 years. We found that voicing during beatboxing was not the same as full voice to have sustained phonation interlaced with percussive sounds. Performers overall demonstrated similarities in delivery of the same beatbox sounds, although subtle differences were noted between performers. Beatboxing is a complex form of vocal percussion using the entire vocal tract. Although similarities with singing in the anatomical structures and positioning are noted in beatboxing, there are several unique and interesting anatomical processes occurring. Use of the entire vocal tract, including the pharyngeal constrictors, may actually protect against glottic injury. Copyright © 2014 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  14. Achieving diagnosis by consensus

    LENUS (Irish Health Repository)

    Kane, Bridget

    2009-08-01

    This paper provides an analysis of the collaborative work conducted at a multidisciplinary medical team meeting, where a patient’s definitive diagnosis is agreed, by consensus. The features that distinguish this process of diagnostic work by consensus are examined in depth. The current use of technology to support this collaborative activity is described, and experienced deficiencies are identified. Emphasis is placed on the visual and perceptual difficulty for individual specialities in making interpretations, and on how, through collaboration in discussion, definitive diagnosis is actually achieved. The challenge for providing adequate support for the multidisciplinary team at their meeting is outlined, given the multifaceted nature of the setting, i.e. patient management, educational, organizational and social functions, that need to be satisfied.

  15. Achieving Standardization

    DEFF Research Database (Denmark)

    Henningsson, Stefan

    2014-01-01

    competitive, national customs and regional economic organizations are seeking to establish a standardized solution for digital reporting of customs data. However, standardization has proven hard to achieve in the socio-technical e-Customs solution. In this chapter, the authors identify and describe what has...

  16. Achieving Standardization

    DEFF Research Database (Denmark)

    Henningsson, Stefan

    2016-01-01

    competitive, national customs and regional economic organizations are seeking to establish a standardized solution for digital reporting of customs data. However, standardization has proven hard to achieve in the socio-technical e-Customs solution. In this chapter, the authors identify and describe what has...

  17. Achieving professionalism

    Directory of Open Access Journals (Sweden)

    R.A.E. Thompson

    1983-09-01

    Full Text Available In approaching the subject of professionalism the author has chosen to focus on the practical aspects rather than the philosophical issues. In so doing an attempt is made to identify criteria which demonstrate the achievement of the essence of professionalism.

  18. An analysis of the impact of three high school schedules on student achievement in advanced placement biology classes

    Science.gov (United States)

    Arons-Polan, Bonnie

    This study examined the effect of three schedule types on student achievement in Advanced Placement Biology classes. AP Biology test scores from students on three types of full-year schedules were analyzed to assess the impact schedule type had on student achievement. The three schedules included the block and traditional schedules, and the rotating/hybrid, a blend of the former two schedules. The results indicated the variable most closely associated with success on the AP Biology exam was the length of experience the teachers had teaching the course, regardless of schedule type. Although significant differences were seen in mean AP Biology test scores among the three schedule types, this could be explained by the relationship between instructors' experience and schedule type. Regression analysis determined the two strongest predictors of successful performance on the AP Biology exam were instructors' experience and perceived teaching style, regardless of schedule type. It appears that the economically developed suburbs, had teachers with the largest amount of experience teaching AP Biology, and these teachers reported using a direct approach to teaching, using lecture greater than 50% of the time. The results of this study also suggest when restructuring to improve student achievement, educators should examine other variables in addition to the high school schedule. Restructuring the day to allow for longer classes must be accompanied by professional staff development to allow teachers to develop new teaching methods. Most of the teachers in the survey reported using lecture a great deal of the time, regardless of schedule type. Comments from the teachers from the various schedules revealed that the ability to add student centered, inquiry based activities and labs were dependent on adequate class time. No information on whether or not the teachers were given professional development to expand their repertoire of teaching methods when the school adopted a block

  19. Alternative Analysis of Classifications of Universal Managerial Functions

    Directory of Open Access Journals (Sweden)

    Chornii Heorhii M.

    2014-03-01

    Full Text Available The article is devoted to theoretical justification of classification of general managerial functions. Critical analysis of scientific works of eminent specialists in management gave a possibility to find out that classification of functions of the subject of management should be based on the objective cyclic change of the state of information by three stages: appearance of information, its concentration and transformation into a programme of specific actions. The article offers a classification model of the integrated managerial activity in social and mixed systems, which includes differentiation of managerial functions into three orders. Providing information, decision making and realisation of the decision are functions of the second order (basic in this model, while accounting, analysis, goal setting, planning, organisation, management and control – are, consequently, functions of the third order (derivatives. The article considers one specific example from management practice with the aim of verification of the author’s opinion regarding the processed classification of managerial functions.

  20. Using functional analysis diagrams to improve product reliability and cost

    Directory of Open Access Journals (Sweden)

    Ioannis Michalakoudis

    2016-12-01

    Full Text Available Failure mode and effects analysis and value engineering are well-established methods in the manufacturing industry, commonly applied to optimize product reliability and cost, respectively. Both processes, however, require cross-functional teams to identify and evaluate the product/process functions and are resource-intensive, hence their application is mostly limited to large organizations. In this article, we present a methodology involving the concurrent execution of failure mode and effects analysis and value engineering, assisted by a set of hierarchical functional analysis diagram models, along with the outcomes of a pilot application in a UK-based manufacturing small and medium enterprise. Analysis of the results indicates that this new approach could significantly enhance the resource efficiency and effectiveness of both failure mode and effects analysis and value engineering processes.

  1. Analyzing coastal environments by means of functional data analysis

    Science.gov (United States)

    Sierra, Carlos; Flor-Blanco, Germán; Ordoñez, Celestino; Flor, Germán; Gallego, José R.

    2017-07-01

    Here we used Functional Data Analysis (FDA) to examine particle-size distributions (PSDs) in a beach/shallow marine sedimentary environment in Gijón Bay (NW Spain). The work involved both Functional Principal Components Analysis (FPCA) and Functional Cluster Analysis (FCA). The grainsize of the sand samples was characterized by means of laser dispersion spectroscopy. Within this framework, FPCA was used as a dimension reduction technique to explore and uncover patterns in grain-size frequency curves. This procedure proved useful to describe variability in the structure of the data set. Moreover, an alternative approach, FCA, was applied to identify clusters and to interpret their spatial distribution. Results obtained with this latter technique were compared with those obtained by means of two vector approaches that combine PCA with CA (Cluster Analysis). The first method, the point density function (PDF), was employed after adapting a log-normal distribution to each PSD and resuming each of the density functions by its mean, sorting, skewness and kurtosis. The second applied a centered-log-ratio (clr) to the original data. PCA was then applied to the transformed data, and finally CA to the retained principal component scores. The study revealed functional data analysis, specifically FPCA and FCA, as a suitable alternative with considerable advantages over traditional vector analysis techniques in sedimentary geology studies.

  2. Functional Principal Components Analysis of Shanghai Stock Exchange 50 Index

    Directory of Open Access Journals (Sweden)

    Zhiliang Wang

    2014-01-01

    Full Text Available The main purpose of this paper is to explore the principle components of Shanghai stock exchange 50 index by means of functional principal component analysis (FPCA. Functional data analysis (FDA deals with random variables (or process with realizations in the smooth functional space. One of the most popular FDA techniques is functional principal component analysis, which was introduced for the statistical analysis of a set of financial time series from an explorative point of view. FPCA is the functional analogue of the well-known dimension reduction technique in the multivariate statistical analysis, searching for linear transformations of the random vector with the maximal variance. In this paper, we studied the monthly return volatility of Shanghai stock exchange 50 index (SSE50. Using FPCA to reduce dimension to a finite level, we extracted the most significant components of the data and some relevant statistical features of such related datasets. The calculated results show that regarding the samples as random functions is rational. Compared with the ordinary principle component analysis, FPCA can solve the problem of different dimensions in the samples. And FPCA is a convenient approach to extract the main variance factors.

  3. A Top Level Analysis of Training Management Functions.

    Science.gov (United States)

    Ackerson, Jack

    1995-01-01

    Discusses how to conduct a top-level analysis of training management functions to identify problems within a training system resulting from rapid growth, the acquisition of new departments, or mergers. The data gathering process and analyses are explained, training management functions and activities are described, and root causes and solutions…

  4. Functional Analysis and Treatment of Inappropriate Sexual Behavior.

    Science.gov (United States)

    Fyffe, Christie E.; Kahng, SungWoo; Fittro, Ellen; Russell, David

    2004-01-01

    The results of a functional analysis showed that inappropriate sexual behaviors exhibited by a 9-year-old boy who had been diagnosed with traumatic brain injury were maintained by positive reinforcement in the form of social attention. An intervention consisting of functional communication training and extinction resulted in reduced levels of…

  5. Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions

    DEFF Research Database (Denmark)

    Pendle, Alison F; Clark, Gillian P; Boon, Reinier

    2005-01-01

    The eukaryotic nucleolus is involved in ribosome biogenesis and a wide range of other RNA metabolism and cellular functions. An important step in the functional analysis of the nucleolus is to determine the complement of proteins of this nuclear compartment. Here, we describe the first proteomic ...

  6. Emerging Themes in the Functional Analysis of Problem Behavior.

    Science.gov (United States)

    Carr, Edward G.

    1994-01-01

    The successful application of functional analysis to problem behavior suggests the need to examine: additional functional properties of behavior involving social avoidance, biological reinforcement, and respondent conditioning; the role of context (including social factors and biological factors); and the multidimensional character of assessment…

  7. Electromagnetic and seismoelectric sensitivity analysis using resolution functions

    NARCIS (Netherlands)

    Maas, P.J.; Grobbe, N.; Slob, E.C.; Mulder, W.A.

    2015-01-01

    For multi-parameter problems, such as the seismoelectric system, sensitivity analysis through resolution functions is a low-cost, fast method of determining whether measured fields are sensitive to certain subsurface parameters. We define a seismoelectric resolution function for the inversion of a

  8. FUNCTIONAL ANALYSIS OF THE WEBBING USED IN AUTO SEATBELTS

    Directory of Open Access Journals (Sweden)

    DRUG (LUCA Alexandra

    2016-05-01

    Full Text Available The reason this paper was made was to identify the functions with the highest importance factor of webbing used in auto seatbelts. For these functions to satisfy all the requirements of operating, functions resulted from analyzing the properties of the webbing. Depending on the importance of each function was developed an objective hierarchy of them, pursuing the imposed decisions technic. Using the Analysis and engineering value it was possible to do the functional analysis of the properties of webbing. By setting the functions value it was possible to obtain a series of decisions, specifying that a function corresponds to a single operating property. Following this analysis it was observed that the main characteristic of webbings is that they have a very good resistance to tensile stresses, characteristic imposed by the manner of operation during use. An important factor that was taken into account in analyzing the webbings was the fabric structure. The structure has a major impact on the function and use of webbings in the belt assembly, considering the fact that their primary role is to save the life of the user, in case of impact of a vehicle. Based on this study the following research is focused on the functional properties of the seatbelt, in order to design and manufacture seatbelts with appropriate exploitation properties.

  9. Molecular characterization and functional analysis of elite genes in wheat and its related species

    Indian Academy of Sciences (India)

    Jirui Wang; Pengfei Qi; Yuming Wei; Dengcai Liu; George Fedak; Youliang Zheng

    2010-12-01

    The tribe Triticeae includes major cereal crops (bread wheat, durum wheat, triticale, barley and rye), as well as abundant forage and lawn grasses. Wheat and its wild related species possess numerous favourable genes for yield improvement, grain quality enhancement, biotic and abiotic stress resistance, and constitute a giant gene pool for wheat improvement. In recent years, significant progress on molecular characterization and functional analysis of elite genes in wheat and its related species have been achieved. In this paper, we review the cloned functional genes correlated with grain quality, biotic and abiotic stress resistance, photosystem and nutrition utilization in wheat and its related species.

  10. Use of Analog Functional Analysis in Assessing the Function of Mealtime Behavior Problems.

    Science.gov (United States)

    Girolami, Peter A.; Scotti, Joseph R.

    2001-01-01

    This study applied the methodology of an analog experimental (functional) analysis of behavior to the specific interaction between parents and three children with mental retardation exhibiting food refusal and related mealtime problems. Analog results were highly consistent with other forms of functional assessment data, including interviews,…

  11. A Temporal Extension to Traditional Empirical Orthogonal Function Analysis

    DEFF Research Database (Denmark)

    Nielsen, Allan Aasbjerg; Hilger, Klaus Baggesen; Andersen, Ole Baltazar

    2002-01-01

    This paper describes the application of temporal maximum autocorrelation factor analysis to global monthly mean values of 1996-1997 sea surface temperature (SST) and sea surface height (SSH) data. This type of analysis can be considered as an extension of traditional empirical orthogonal function...

  12. Structural analysis and functional characteristics of greenhouses in ...

    African Journals Online (AJOL)

    USER

    2010-05-24

    May 24, 2010 ... This study was carried out to determine the structural analysis and functional characteristics of the greenhouses ..... Duncan test results for mean separation of calculated stretch ratios, ... and Organic Fertilizers and Possible Effects in the Greenhouses of ... Structural analysis of greenhouses: A case study in.

  13. Complex analysis a modern first course in function theory

    CERN Document Server

    Muir, Jerry R

    2015-01-01

    A thorough introduction to the theory of complex functions emphasizing the beauty, power, and counterintuitive nature of the subject Written with a reader-friendly approach, Complex Analysis: A Modern First Course in Function Theory features a self-contained, concise development of the fundamental principles of complex analysis. After laying groundwork on complex numbers and the calculus and geometric mapping properties of functions of a complex variable, the author uses power series as a unifying theme to define and study the many rich and occasionally surprising properties of analytic fun

  14. Advances and Achievements in In Situ Analysis of Corrosion and Structure–Property Relationship in Mg Alloys

    Energy Technology Data Exchange (ETDEWEB)

    Orlov, D.; Joshi, V.

    2016-11-03

    Every year, TMS Magnesium Committee carefully selects a special topic in magnesium (Mg) related research and development not only having the hottest subject from both academic and industrial perspectives but also demonstrating major achievements within this subject. Following last year’s topic on Mg microallying [1], this year’s focus is on in-situ methods and associated techniques in their broad definition spanning from laboratory- to large- scale facilities to process monitoring. The applications of in-situ techniques have a wide spectrum from the analysis of melts and liquid-solid transitions to solid-state phenomena during thermo-mechanical processing and heat treatments to surface interactions with various environments. Therefore, such works are of significant interest to scientists working in the area of Mg alloy development as well as to a much broader audience from both academia and industry. This interest is primarily caused by challenges in the analysis of structure-property relationship in Mg alloys, and even cursory glance of literature reveals sharp increase of publications relevant to this topic recently. For instance, very high reactivity of Mg as well as its well-known propensity to substantially alter structure upon unloading in mechanical testing makes it difficult to understand and thus to simulate correlation between microstructures observed in post-mortem analysis and physical processes during testing or fabrication. However, recent advances in in-situ analysis based on large-scale research facilities such as neutron scattering and synchrotron radiation sources as well as microscopy-based, acoustic emission, and other more traditional techniques allowed significant achievements. Apart from apparent development of relevant experimental techniques, a significant part of this success should also be attributed to increasing accessibility of the facilities and simplification of their use from a user perspective. The selection of articles in this

  15. An analysis of predictors of enrollment and successful achievement for girls in high school Advanced Placement physics

    Science.gov (United States)

    Depalma, Darlene M.

    A problem within science education in the United States persists. U.S students rank lower in science than most other students from participating countries on international tests of achievement (National Center for Education Statistics, 2003). In addition, U.S. students overall enrollment rate in high school Advanced Placement (AP) physics is still low compared to other academic domains, especially for females. This problem is the background for the purpose of this study. This investigation examined cognitive and motivational variables thought to play a part in the under-representation of females in AP physics. Cognitive variables consisted of mathematics, reading, and science knowledge, as measured by scores on the 10th and 11th grade Florida Comprehensive Assessment Tests (FCAT). The motivational factors of attitude, stereotypical views toward science, self-efficacy, and epistemological beliefs were measured by a questionnaire developed with questions taken from previously proven reliable and valid instruments. A general survey regarding participation in extracurricular activities was also included. The sample included 12th grade students from two high schools located in Seminole County, Florida. Of the 106 participants, 20 girls and 27 boys were enrolled in AP physics, and 39 girls and 20 boys were enrolled in other elective science courses. Differences between males and females enrolled in AP physics were examined, as well as differences between females enrolled in AP physics and females that chose not to participate in AP physics, in order to determine predictors that apply exclusively to female enrollment in high school AP physics and predictors of an anticipated science related college major. Data were first analyzed by Exploratory Factor Analysis, followed by Analysis of Variance (ANOVA), independent t-tests, univariate analysis, and logistic regression analysis. One overall theme that emerged from this research was findings that refute the ideas that

  16. Advanced functionality for radio analysis in the Offline software framework of the Pierre Auger Observatory

    Science.gov (United States)

    Abreu, P.; Aglietta, M.; Ahn, E. J.; Albuquerque, I. F. M.; Allard, D.; Allekotte, I.; Allen, J.; Allison, P.; Alvarez Castillo, J.; Alvarez-Muñiz, J.; Ambrosio, M.; Aminaei, A.; Anchordoqui, L.; Andringa, S.; Antičić, T.; Aramo, C.; Arganda, E.; Arqueros, F.; Asorey, H.; Assis, P.; Aublin, J.; Ave, M.; Avenier, M.; Avila, G.; Bäcker, T.; Balzer, M.; Barber, K. B.; Barbosa, A. F.; Bardenet, R.; Barroso, S. L. C.; Baughman, B.; Beatty, J. J.; Becker, B. R.; Becker, K. H.; Bellido, J. A.; Benzvi, S.; Berat, C.; Bertou, X.; Biermann, P. L.; Billoir, P.; Blanco, F.; Blanco, M.; Bleve, C.; Blümer, H.; Boháčová, M.; Boncioli, D.; Bonifazi, C.; Bonino, R.; Borodai, N.; Brack, J.; Brogueira, P.; Brown, W. C.; Bruijn, R.; Buchholz, P.; Bueno, A.; Burton, R. E.; Caballero-Mora, K. S.; Caramete, L.; Caruso, R.; Castellina, A.; Cataldi, G.; Cazon, L.; Cester, R.; Chauvin, J.; Chiavassa, A.; Chinellato, J. A.; Chou, A.; Chudoba, J.; Clay, R. W.; Coluccia, M. R.; Conceição, R.; Contreras, F.; Cook, H.; Cooper, M. J.; Coppens, J.; Cordier, A.; Cotti, U.; Coutu, S.; Covault, C. E.; Creusot, A.; Criss, A.; Cronin, J.; Curutiu, A.; Dagoret-Campagne, S.; Dallier, R.; Dasso, S.; Daumiller, K.; Dawson, B. R.; de Almeida, R. M.; de Domenico, M.; de Donato, C.; de Jong, S. J.; de La Vega, G.; de Mello Junior, W. J. M.; de Mello Neto, J. R. T.; de Mitri, I.; de Souza, V.; de Vries, K. D.; Decerprit, G.; Del Peral, L.; Deligny, O.; Dembinski, H.; Denkiewicz, A.; di Giulio, C.; Diaz, J. C.; Díaz Castro, M. L.; Diep, P. N.; Dobrigkeit, C.; D'Olivo, J. C.; Dong, P. N.; Dorofeev, A.; Dos Anjos, J. C.; Dova, M. T.; D'Urso, D.; Dutan, I.; Ebr, J.; Engel, R.; Erdmann, M.; Escobar, C. O.; Etchegoyen, A.; Facal San Luis, P.; Falcke, H.; Farrar, G.; Fauth, A. C.; Fazzini, N.; Ferguson, A. P.; Ferrero, A.; Fick, B.; Filevich, A.; Filipčič, A.; Fliescher, S.; Fracchiolla, C. E.; Fraenkel, E. D.; Fröhlich, U.; Fuchs, B.; Gamarra, R. F.; Gambetta, S.; García, B.; García Gámez, D.; Garcia-Pinto, D.; Gascon, A.; Gemmeke, H.; Gesterling, K.; Ghia, P. L.; Giaccari, U.; Giller, M.; Glass, H.; Gold, M. S.; Golup, G.; Gomez Albarracin, F.; Gómez Berisso, M.; Gonçalves, P.; Gonzalez, D.; Gonzalez, J. G.; Gookin, B.; Góra, D.; Gorgi, A.; Gouffon, P.; Gozzini, S. R.; Grashorn, E.; Grebe, S.; Griffith, N.; Grigat, M.; Grillo, A. F.; Guardincerri, Y.; Guarino, F.; Guedes, G. P.; Hague, J. D.; Hansen, P.; Harari, D.; Harmsma, S.; Harton, J. L.; Haungs, A.; Hebbeker, T.; Heck, D.; Herve, A. E.; Hojvat, C.; Holmes, V. C.; Homola, P.; Hörandel, J. R.; Horneffer, A.; Hrabovský, M.; Huege, T.; Insolia, A.; Ionita, F.; Italiano, A.; Jiraskova, S.; Kadija, K.; Kampert, K. H.; Karhan, P.; Karova, T.; Kasper, P.; Kégl, B.; Keilhauer, B.; Keivani, A.; Kelley, J. L.; Kemp, E.; Kieckhafer, R. M.; Klages, H. O.; Kleifges, M.; Kleinfeller, J.; Knapp, J.; Koang, D.-H.; Kotera, K.; Krohm, N.; Krömer, O.; Kruppke-Hansen, D.; Kuehn, F.; Kuempel, D.; Kulbartz, J. K.; Kunka, N.; La Rosa, G.; Lachaud, C.; Lautridou, P.; Leão, M. S. A. B.; Lebrun, D.; Lebrun, P.; Leigui de Oliveira, M. A.; Lemiere, A.; Letessier-Selvon, A.; Lhenry-Yvon, I.; Link, K.; López, R.; Lopez Agüera, A.; Louedec, K.; Lozano Bahilo, J.; Lucero, A.; Ludwig, M.; Lyberis, H.; Macolino, C.; Maldera, S.; Mandat, D.; Mantsch, P.; Mariazzi, A. G.; Marin, V.; Maris, I. C.; Marquez Falcon, H. R.; Marsella, G.; Martello, D.; Martin, L.; Martínez Bravo, O.; Mathes, H. J.; Matthews, J.; Matthews, J. A. J.; Matthiae, G.; Maurizio, D.; Mazur, P. O.; Medina-Tanco, G.; Melissas, M.; Melo, D.; Menichetti, E.; Menshikov, A.; Mertsch, P.; Meurer, C.; Mićanović, S.; Micheletti, M. I.; Miller, W.; Miramonti, L.; Mollerach, S.; Monasor, M.; Monnier Ragaigne, D.; Montanet, F.; Morales, B.; Morello, C.; Moreno, E.; Moreno, J. C.; Morris, C.; Mostafá, M.; Moura, C. A.; Mueller, S.; Muller, M. A.; Müller, G.; Münchmeyer, M.; Mussa, R.; Navarra, G.; Navarro, J. L.; Navas, S.; Necesal, P.; Nellen, L.; Nelles, A.; Nhung, P. T.; Nierstenhoefer, N.; Nitz, D.; Nosek, D.; Nožka, L.; Nyklicek, M.; Oehlschläger, J.; Olinto, A.; Oliva, P.; Olmos-Gilbaja, V. M.; Ortiz, M.; Pacheco, N.; Pakk Selmi-Dei, D.; Palatka, M.; Pallotta, J.; Palmieri, N.; Parente, G.; Parizot, E.; Parra, A.; Parrisius, J.; Parsons, R. D.; Pastor, S.; Paul, T.; Pech, M.; PeĶala, J.; Pelayo, R.; Pepe, I. M.; Perrone, L.; Pesce, R.; Petermann, E.; Petrera, S.; Petrinca, P.; Petrolini, A.; Petrov, Y.; Petrovic, J.; Pfendner, C.; Phan, N.; Piegaia, R.; Pierog, T.; Pieroni, P.; Pimenta, M.; Pirronello, V.; Platino, M.; Ponce, V. H.; Pontz, M.; Privitera, P.; Prouza, M.; Quel, E. J.; Rautenberg, J.; Ravel, O.; Ravignani, D.; Revenu, B.; Ridky, J.; Risse, M.; Ristori, P.; Rivera, H.; Riviére, C.; Rizi, V.; Robledo, C.; Rodrigues de Carvalho, W.; Rodriguez, G.; Rodriguez Martino, J.; Rodriguez Rojo, J.; Rodriguez-Cabo, I.; Rodríguez-Frías, M. D.; Ros, G.; Rosado, J.; Rossler, T.; Roth, M.; Rouillé-D'Orfeuil, B.; Roulet, E.; Rovero, A. C.; Rühle, C.; Salamida, F.; Salazar, H.; Salina, G.; Sánchez, F.; Santander, M.; Santo, C. E.; Santos, E.; Santos, E. M.; Sarazin, F.; Sarkar, S.; Sato, R.; Scharf, N.; Scherini, V.; Schieler, H.; Schiffer, P.; Schmidt, A.; Schmidt, F.; Schmidt, T.; Scholten, O.; Schoorlemmer, H.; Schovancova, J.; Schovánek, P.; Schroeder, F.; Schulte, S.; Schuster, D.; Sciutto, S. J.; Scuderi, M.; Segreto, A.; Semikoz, D.; Settimo, M.; Shadkam, A.; Shellard, R. C.; Sidelnik, I.; Sigl, G.; Śmiałkowski, A.; Šmída, R.; Snow, G. R.; Sommers, P.; Sorokin, J.; Spinka, H.; Squartini, R.; Stapleton, J.; Stasielak, J.; Stephan, M.; Stutz, A.; Suarez, F.; Suomijärvi, T.; Supanitsky, A. D.; Šuša, T.; Sutherland, M. S.; Swain, J.; Szadkowski, Z.; Szuba, M.; Tamashiro, A.; Tapia, A.; Taşcău, O.; Tcaciuc, R.; Tegolo, D.; Thao, N. T.; Thomas, D.; Tiffenberg, J.; Timmermans, C.; Tiwari, D. K.; Tkaczyk, W.; Todero Peixoto, C. J.; Tomé, B.; Tonachini, A.; Travnicek, P.; Tridapalli, D. B.; Tristram, G.; Trovato, E.; Tueros, M.; Ulrich, R.; Unger, M.; Urban, M.; Valdés Galicia, J. F.; Valiño, I.; Valore, L.; van den Berg, A. M.; Vargas Cárdenas, B.; Vázquez, J. R.; Vázquez, R. A.; Veberič, D.; Verzi, V.; Videla, M.; Villaseñor, L.; Wahlberg, H.; Wahrlich, P.; Wainberg, O.; Warner, D.; Watson, A. A.; Weber, M.; Weidenhaupt, K.; Weindl, A.; Westerhoff, S.; Whelan, B. J.; Wieczorek, G.; Wiencke, L.; Wilczyńska, B.; Wilczyński, H.; Will, M.; Williams, C.; Winchen, T.; Winders, L.; Winnick, M. G.; Wommer, M.; Wundheiler, B.; Yamamoto, T.; Younk, P.; Yuan, G.; Zamorano, B.; Zas, E.; Zavrtanik, D.; Zavrtanik, M.; Zaw, I.; Zepeda, A.; Ziolkowski, M.

    2011-04-01

    The advent of the Auger Engineering Radio Array (AERA) necessitates the development of a powerful framework for the analysis of radio measurements of cosmic ray air showers. As AERA performs “radio-hybrid” measurements of air shower radio emission in coincidence with the surface particle detectors and fluorescence telescopes of the Pierre Auger Observatory, the radio analysis functionality had to be incorporated in the existing hybrid analysis solutions for fluorescence and surface detector data. This goal has been achieved in a natural way by extending the existing Auger Offline software framework with radio functionality. In this article, we lay out the design, highlights and features of the radio extension implemented in the Auger Offline framework. Its functionality has achieved a high degree of sophistication and offers advanced features such as vectorial reconstruction of the electric field, advanced signal processing algorithms, a transparent and efficient handling of FFTs, a very detailed simulation of detector effects, and the read-in of multiple data formats including data from various radio simulation codes. The source code of this radio functionality can be made available to interested parties on request.

  17. Securing Communal Land Rights to Achieve Sustainable Development in Sub-Saharan Africa: Critical Analysis and Policy Implications

    Directory of Open Access Journals (Sweden)

    Ross Andrew Clarke

    2009-09-01

    Full Text Available While the concept of sustainable development gains increasing traction under international law, effective and scalable policies to translate these principles into practice remain largely beyond reach. This article analyses one possible strategy in Sub-Saharan Africa - increasing security of communal tenure to improve resource management and achieve rural sustainable development. Although this approach has attracted some attention, particularly with management responsibility of communal property increasingly devolved to the community-level, the expected results in terms of more sustainable resource exploitation and sounder environmental management have yet to be realised. Through critical analysis, with particular emphasis on the Gestion Terroir approach in Burkina Faso , the article explores the reasons behind the limited success. The article suggests that greater emphasis must be placed on bridging statutory command-and-control regimes with community-based models. Focusing on the links between communal land tenure and environmental management, and effectively embedding community land management institutions within existing environmental governance structures offers a practical model to promote sustainable development.

  18. Linear functional analysis an application-oriented introduction

    CERN Document Server

    Alt, Hans Wilhelm

    2016-01-01

    This book gives an introduction to Linear Functional Analysis, a synthesis of algebra, topology, and analysis. In addition to the basic theory it explains operator theory, distributions, Sobolev spaces, and many other things. The text is self-contained and includes all proofs, as well as many exercises, most of them with solutions. Moreover, there are a number of appendices, for example on Lebesgue integration theory. A complete introduction to the subject, Linear Functional Analysis will be particularly useful to readers who want to quickly get to the key statements and who are interested in applications to differential equations.

  19. Functional analysis in the evaluation of four concepts of planters

    Directory of Open Access Journals (Sweden)

    Reis Ângelo Vieira dos

    2002-01-01

    Full Text Available The essential functions of a planter are to open the planting furrow, meter the seeds, deposit them in the furrow, cover them and compact the soil around them. The planter precision is affected, in some way, by each of those functions. Function analysis is a tool used in the conceptual phase of product design which allows an abstract formulation for the function of the technical system, thus making it very useful in product design and in the analysis of existing products. Therefore, the technique of function analysis makes it possible to identify, in the various concepts of planters sold in the Brazilian market, which function is not well implemented when considering precision planting of small grains, being this the main objective of this study. This study has made it possible to conclude, among other things, that in all concepts of planters analyzed, the sub-functions of metering seeds and that of depositing seeds in the soil were not satisfactorily implemented for the precision planting of small grains. This points out the need of searching for other concepts of planters or the adoption of different solution principles for these functions.

  20. Applying Cognitive Work Analysis to Time Critical Targeting Functionality

    Science.gov (United States)

    2004-10-01

    Target List/Dynamic Target Queue (DTL/ DTQ ) in the same place. Figure 4-27 shows the task steps involved in achieving Goal 7. 4- 30 Figure 4-27...GUI WG to brainstorm the order of columns in the DTL/ DTQ Table, a critical component of the TCTF CUI, with successful results, which were...Cognitive Work Analysis DTD Display Task Description DTL/ DTQ Dynamic Target List/Dynamic Target Queue FDO Fighter Duty Officer FEBA Forward Edge

  1. An Analysis of Taiwanese Eighth Graders' Science Achievement, Scientific Epistemological Beliefs and Cognitive Structure Outcomes After Learning Basic Atomic Theory.

    Science.gov (United States)

    Tsai, Chin-Chung

    1998-01-01

    Explores the interrelationships between students' general science achievement, scientific epistemological beliefs, and cognitive structure outcomes derived from instruction of basic atomic theory. Contains 19 references. (DDR)

  2. Generalized functions, volume 4 applications of harmonic analysis

    CERN Document Server

    Gel′fand, I M; Vilenkin, N Ya

    2016-01-01

    The first systematic theory of generalized functions (also known as distributions) was created in the early 1950s, although some aspects were developed much earlier, most notably in the definition of the Green's function in mathematics and in the work of Paul Dirac on quantum electrodynamics in physics. The six-volume collection, Generalized Functions, written by I. M. Gel′fand and co-authors and published in Russian between 1958 and 1966, gives an introduction to generalized functions and presents various applications to analysis, PDE, stochastic processes, and representation theory. The main

  3. A Functional Analysis of the Comprehensive Application of Behavior Analysis to Schooling.

    Science.gov (United States)

    Selinske, Jane E.; And Others

    1991-01-01

    Behavior analysis was implemented in a school for 38 children with multiple disabilities, following staff training. Results over two years showed educationally significant increases in trials taught, correct student trials, and objectives achieved. During followup, results indicated maintenance and social validity of the behavior analysis package.…

  4. Cognitive Processes and Achievement.

    Science.gov (United States)

    Hunt, Dennis; Randhawa, Bikkar S.

    For a group of 165 fourth- and fifth-grade students, four achievement test scores were correlated with success on nine tests designed to measure three cognitive functions: sustained attention, successive processing, and simultaneous processing. This experiment was designed in accordance with Luria's model of the three functional units of the…

  5. Cognitive Processes and Achievement.

    Science.gov (United States)

    Hunt, Dennis; Randhawa, Bikkar S.

    For a group of 165 fourth- and fifth-grade students, four achievement test scores were correlated with success on nine tests designed to measure three cognitive functions: sustained attention, successive processing, and simultaneous processing. This experiment was designed in accordance with Luria's model of the three functional units of the…

  6. Mobile multimedia antenna systems for station wagons and the achievable diversity effectiveness obtained by analysis of virtual test drives

    Science.gov (United States)

    Hopf, J. F.; Lindenmeier, H. K.; Reiter, L. M.

    2003-04-01

    For modern cars, antennas are required for AM reception, FM and TV diversity reception, weatherband reception (USA), terrestrial digital radio, remote control functions, keyless entry, mobile phone for all worldwide used systems, GPS, and in the future, satellite broadcast radio services. Those services cover the frequency range from 150 kHz up to 2.4 GHz. Such kind of a multiantenna system developed for station wagons is presented in this paper. The obtainable FM and TV diversity effectiveness is discussed for several types of antenna arrangements in detail. This value is the number of fictitious completely decorrelated antenna signals and is obtained by virtual test drives. The characteristic of the respective antennas under test is introduced in the software as antenna pattern, measured or calculated with respect to amplitude and phase. During the computer analysis the car with the antennas is driven virtually through a Rayleigh field scenario with desired and undesired signals.

  7. Highly Functional TNTs with Superb Photocatalytic, Optical, and Electronic Performance Achieving Record PV Efficiency of 10.1% for 1D-Based DSSCs.

    Science.gov (United States)

    Qadir, Muhammad Bilal; Li, Yuewen; Sahito, Iftikhar Ali; Arbab, Alvira Ayoub; Sun, Kyung Chul; Mengal, Naveed; Memon, Anam Ali; Jeong, Sung Hoon

    2016-09-01

    Different nanostructures of TiO2 play an important role in the photocatalytic and photoelectronic applications. TiO2 nanotubes (TNTs) have received increasing attention for these applications due to their unique physicochemical properties. Focusing on highly functional TNTs (HF-TNTs) for photocatalytic and photoelectronic applications, this study describes the facile hydrothermal synthesis of HF-TNTs by using commercial and cheaper materials for cost-effective manufacturing. To prove the functionality and applicability, these TNTs are used as scattering structure in dye-sensitized solar cells (DSSCs). Photocatalytic, optical, Brunauer-Emmett-Teller (BET), electrochemical impedance spectrum, incident-photon-to-current efficiency, and intensity-modulated photocurrent spectroscopy/intensity-modulated photovoltage spectroscopy characterizations are proving the functionality of HF-TNTs for DSSCs. HF-TNTs show 50% higher photocatalytic degradation rate and also 68% higher dye loading ability than conventional TNTs (C-TNTs). The DSSCs having HF-TNT and its composite-based multifunctional overlayer show effective light absorption, outstanding light scattering, lower interfacial resistance, longer electron lifetime, rapid electron transfer, and improved diffusion length, and consequently, J SC , quantum efficiency, and record photoconversion efficiency of 10.1% using commercial N-719 dye is achieved, for 1D-based DSSCs. These new and highly functional TNTs will be a concrete fundamental background toward the development of more functional applications in fuel cells, dye-sensitized solar cells, Li-ion batteries, photocatalysis process, ion-exchange/adsorption process, and photoelectrochemical devices. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Transfer function analysis of ultrasonic time-intensity measurements.

    Science.gov (United States)

    Li, Pai-Chi; Yang, Mei-Ju

    2003-10-01

    Time-intensity measurements of ultrasonic-contrast microbubbles based on the dilution theory have been used to assist blood flow estimation. The compartment model has been employed to describe the dilution process. Under the linear and time-invariant assumption, the time-intensity curve measured at the output of a compartment (i.e., blood mixing chamber) is the convolution of the input time-intensity curve with the compartment's transfer function. Thus, transfer function analysis is possible using deconvolution when the temporal variations in both the input and the output intensities are available. Note that the linear and time-invariant assumption requires a constant flow rate because, with flow pulsation, the flow rate changes with time and the mixing process becomes time varying. Thus, the purpose of this paper was to study the effects of flow pulsation on time-intensity measurements. In addition, a deconvolution technique based on a recursive least squares approach is used for transfer function analysis. Both simulations and experiments were performed; the results from which indicate that the pulsation generally does not affect the validity of time-intensity-based flow estimation. The proposed deconvolution technique is also effective for both constant and pulsatile flows; thus, permitting transfer function analysis in various flow conditions. One potential application of this transfer function analysis is to remove the effects of a noninstantaneous input function. The results from this paper lead to future work in brain-perfusion estimation based on extracranial time-intensity measurements.

  9. An Analysis of the Impact of Demographic, Structural, Student, and Financial Factors on Texas High School Mathematics Achievement

    Science.gov (United States)

    Carter, Alisa

    2013-01-01

    The purpose of this study was to examine the relationships of demographic (indicators describing student characteristics), structural (indicators describing school characteristics), student (indicators of student academic achievement), and financial (indicators of instructional expenditures) factors to student mathematics achievement. A sample (n…

  10. Parental Characteristics and the Achievement Gap in Mathematics: Hierarchical Linear Modeling Analysis of Longitudinal Study of American Youth (LSAY)

    Science.gov (United States)

    Shoraka, Mohammad; Arnold, Robert; Kim, Eun Sook; Salinitri, Geri; Kromrey, Jeffrey

    2015-01-01

    One of the most salient problems in education is the achievement gap. The researchers investigated the effects of parental education and parental occupations in science, technology, engineering, mathematics, or medical professions (STEMM) on the achievement gap in mathematics. Because students were nested within schools, two-level Hierarchical…

  11. The Effectiveness of Educational Technology Applications for Enhancing Mathematics Achievement in K-12 Classrooms: A Meta-Analysis. Educator's Summary

    Science.gov (United States)

    Center for Research and Reform in Education, 2012

    2012-01-01

    This review summarizes research on the effects of technology use on mathematics achievement in K-12 classrooms. The main research questions included: (1) Do education technology applications improve mathematics achievement in K-12 classrooms as compared to traditional teaching methods without education technology?; and (2) What study and research…

  12. Parental Characteristics and the Achievement Gap in Mathematics: Hierarchical Linear Modeling Analysis of Longitudinal Study of American Youth (LSAY)

    Science.gov (United States)

    Shoraka, Mohammad; Arnold, Robert; Kim, Eun Sook; Salinitri, Geri; Kromrey, Jeffrey

    2015-01-01

    One of the most salient problems in education is the achievement gap. The researchers investigated the effects of parental education and parental occupations in science, technology, engineering, mathematics, or medical professions (STEMM) on the achievement gap in mathematics. Because students were nested within schools, two-level Hierarchical…

  13. A Cultural Analysis of the Achievement Gap Discourse: Challenging the Language and Labels Used in the Work of School Reform

    Science.gov (United States)

    Carey, Roderick L.

    2014-01-01

    In this article, I critique the labels and terms used to frame practices aimed at closing the achievement gap. I examine how an unacknowledged "achievement gap Discourse" has emerged from the language that informs practices and policies of contemporary school reform. I use Gee's uppercase "Discourse" and a cultural analytic…

  14. Surface analysis of gold nanoparticles functionalized with thiol-modified glucose SAMs for biosensor applications.

    Directory of Open Access Journals (Sweden)

    Valentina eSpampinato

    2016-02-01

    Full Text Available In this work, Time of Flight Secondary Ion Mass Spectrometry (ToF-SIMS, Principal Component Analysis (PCA and X-ray Photoelectron Spectroscopy (XPS have been used to characterize the surface chemistry of gold substrates before and after functionalization with thiol-modified glucose self-assembled monolayers and subsequent biochemical specific recognition of maltose binding protein (MBP.The results indicate that the surface functionalization is achieved both on flat and nanoparticles gold substrates thus showing the potential of the developed system as biodetection platform. Moreover, the method presented here has been found to be a sound and valid approach to characterize the surface chemistry of nanoparticles functionalized with large molecules.Both techniques were proved to be very useful tools for monitoring all the functionalization steps, including the investigation of the biological behaviour of the glucose-modified particles in presence of the maltose binding protein.

  15. Natural selection on functional modules, a genome-wide analysis.

    Science.gov (United States)

    Serra, François; Arbiza, Leonardo; Dopazo, Joaquín; Dopazo, Hernán

    2011-03-01

    Classically, the functional consequences of natural selection over genomes have been analyzed as the compound effects of individual genes. The current paradigm for large-scale analysis of adaptation is based on the observed significant deviations of rates of individual genes from neutral evolutionary expectation. This approach, which assumed independence among genes, has not been able to identify biological functions significantly enriched in positively selected genes in individual species. Alternatively, pooling related species has enhanced the search for signatures of selection. However, grouping signatures does not allow testing for adaptive differences between species. Here we introduce the Gene-Set Selection Analysis (GSSA), a new genome-wide approach to test for evidences of natural selection on functional modules. GSSA is able to detect lineage specific evolutionary rate changes in a notable number of functional modules. For example, in nine mammal and Drosophilae genomes GSSA identifies hundreds of functional modules with significant associations to high and low rates of evolution. Many of the detected functional modules with high evolutionary rates have been previously identified as biological functions under positive selection. Notably, GSSA identifies conserved functional modules with many positively selected genes, which questions whether they are exclusively selected for fitting genomes to environmental changes. Our results agree with previous studies suggesting that adaptation requires positive selection, but not every mutation under positive selection contributes to the adaptive dynamical process of the evolution of species.

  16. Natural selection on functional modules, a genome-wide analysis.

    Directory of Open Access Journals (Sweden)

    François Serra

    2011-03-01

    Full Text Available Classically, the functional consequences of natural selection over genomes have been analyzed as the compound effects of individual genes. The current paradigm for large-scale analysis of adaptation is based on the observed significant deviations of rates of individual genes from neutral evolutionary expectation. This approach, which assumed independence among genes, has not been able to identify biological functions significantly enriched in positively selected genes in individual species. Alternatively, pooling related species has enhanced the search for signatures of selection. However, grouping signatures does not allow testing for adaptive differences between species. Here we introduce the Gene-Set Selection Analysis (GSSA, a new genome-wide approach to test for evidences of natural selection on functional modules. GSSA is able to detect lineage specific evolutionary rate changes in a notable number of functional modules. For example, in nine mammal and Drosophilae genomes GSSA identifies hundreds of functional modules with significant associations to high and low rates of evolution. Many of the detected functional modules with high evolutionary rates have been previously identified as biological functions under positive selection. Notably, GSSA identifies conserved functional modules with many positively selected genes, which questions whether they are exclusively selected for fitting genomes to environmental changes. Our results agree with previous studies suggesting that adaptation requires positive selection, but not every mutation under positive selection contributes to the adaptive dynamical process of the evolution of species.

  17. Performance-based tests versus behavioral ratings in the assessment of executive functioning in preschoolers: associations with ADHD symptoms and reading achievement.

    Directory of Open Access Journals (Sweden)

    Ana eMiranda

    2015-04-01

    Full Text Available The early assessment of the executive processes using ecologically valid instruments is essential for identifying deficits and planning actions to deal with possible adverse consequences. The present study has two different objectives. The first objective is to analyze the relationship between preschoolers’ performance on tests of Working Memory and Inhibition and parents’ and teachers’ ratings of these executive functions (EF using the Behavior Rating Inventory of Executive Function (BRIEF. The second objective consists of studying the predictive value of the different EF measures (performance-based test and rating scales on Inattention and Hyperactivity/Impulsivity behaviors and on indicators of word reading performance. The participants in the study were 209 children in the last year of preschool, their teachers and their families. Performance-based tests of Working Memory and Inhibition were administered, as well as word reading measures (accuracy and speed. The parents and teachers filled out rating scales of the EF and typical behaviors of ADHD symptomatology. Moderate correlation values were found between the different EF assessments procedures, although the results varied depending on the different domains. Metacognition index from the BRIEF presented stronger correlations with verbal working memory tests than with inhibition tests. Both the rating scales and the performance-based tests were significant predictors of Inattention and Hyperactivity/Impulsivity behaviors and the reading achievement measures. However, the BRIEF explained a greater percentage of variance in the case of the ADHD symptomatology, while the performance-based tests explained reading achievement to a greater degree. The implications of the findings for research and clinical practice are discussed.

  18. Big fish in big ponds: a multilevel analysis of test anxiety and achievement in special gifted classes.

    Science.gov (United States)

    Goetz, Thomas; Preckel, Franzis; Zeidner, Moshe; Schleyer, Esther

    2008-04-01

    This study analyzes the effects of individual achievement and achievement level of student reference group on test anxiety in a national sample of 769 gifted Israeli students (grade levels 4-9), which was previously investigated by Zeidner and Schleyer (1999a). We hypothesized that when controlling for individual achievement, students' experiences of test anxiety should increase with the increasing ability level of their peer reference group. It was assumed that this effect was largely mediated by reference group effects on academic self-concept (big-fish-little-pond effect). Zeidner and Schleyer found that gifted students within a gifted peer reference group showed higher levels of test anxiety than gifted students within a non-gifted peer reference group. Of note, the present study focused exclusively on gifted students attending special gifted classes. The main research question was whether or not the assumed effects of individual and class achievement can be found for gifted students in special gifted classes when taking the variance of achievement level (grades) of the special gifted classes into account. Using hierarchical linear modeling (HLM) methodology, the assumed effects were vindicated for this special group of high ability students. Thus, in line with previous results, the Worry component of test anxiety was more highly reactive to the effects of individual achievement than the Emotionality component. Also, in line with our theoretical assumptions, achievement/anxiety relations were largely mediated by the effects of academic self-concept.

  19. Academic buoyancy, student's achievement, and the linking role of control: A cross-lagged analysis of high school students.

    Science.gov (United States)

    Collie, Rebecca J; Martin, Andrew J; Malmberg, Lars-Erik; Hall, James; Ginns, Paul

    2015-03-01

    Previous research has indicated that although academic buoyancy and student's achievement are associated, the relationship is relatively modest. We sought to determine whether another construct might link academic buoyancy and student's achievement. Based on prior theoretical and empirical work, we examined a sense of control as one possible linking mechanism. The study analysed data from 2,971 students attending 21 Australian high schools. We conducted a cross-lagged panel design as a first means of disentangling the relative salience of academic buoyancy, control, and achievement (Phase 1). Based upon these results, we proceeded with follow-up analyses of an ordered process model linking the constructs over time (Phase 2). Findings showed that buoyancy and achievement were associated with control over time, but not with one another (Phase 1). In addition, control appeared to play a role in how buoyancy influenced achievement and that a cyclical process may operate among the three factors over time (Phase 2). The findings suggest that control may play an important role in linking past experiences of academic buoyancy and achievement to subsequent academic buoyancy and achievement. © 2015 The British Psychological Society.

  20. Multidisciplinary Analysis of Cyclophilin A Function in Human Breast Cancer

    Science.gov (United States)

    2010-03-01

    diagram of synthetic antibody production, which involves target protein immobilization, phase display library screening , and structural and functional...proteins, phase display library screening , and functional analysis of selected antigen-binding fragments (FABs) (Figure 4A). In brief, recombinant his...display library screening results in the generation of total 18 CypA- specific FABs including CsA sensitive (#1-11) and non CsA-sensitive (#12-18). A free

  1. The Stomatognathic Function Analysis of Skeletal Abnormalities and TMJ Disorders

    OpenAIRE

    1991-01-01

    Recently, stomatognathic function analysis has been recognized as essential to diagnosis and treatment planning, especially in patients with dento-skeletal discrepancies and TMJ disorders. Functional malocclusion should be carefully judged in diagnosis of pre-surgical orthodontic treatment and TMJ disorders. Also, the estimation of the EMG power and jaw movement pathway changes before and after surgery are very effective in estimating the occlusal stability and expectations of post-surgical r...

  2. A Functional Analysis on the Translations Of Deng Guanquelou

    Institute of Scientific and Technical Information of China (English)

    LI Xiao-ting

    2016-01-01

    Systemic functional linguistics is correlated with the translation study for the theory can be applied to analyze and eval-uate the translations. The poem Deng Guanquelou and its translated versions can be approached and compared within the Halli-dayan framework in so far as the translation processes and details can be better comprehended and described. The applicability and operability of functional grammar can be validated by virtue of the analysis of the translations.

  3. Multiresolution Analysis by Infinitely Differentiable Compactly Supported Functions

    Science.gov (United States)

    1992-09-01

    Z 2. Wavelet decompositions The up function provides an interesting example of wavelet decompositions via multiresolution. A general discussion of...Math. Surveys 45:1 (1990), 87-120. [I] (;. Strang and G. Fix, A Fourier analysis of the finite element variational method. C.I.M.F. I 1 Ciclo 1971, in Constructi’c Aspects of Functional Analyszs ed. G. Geymonat 1973, 793-840. 10

  4. Assessing the utility of a demand assessment for functional analysis.

    Science.gov (United States)

    Roscoe, Eileen M; Rooker, Griffin W; Pence, Sacha T; Longworth, Lynlea J

    2009-01-01

    We evaluated the utility of an assessment for identifying tasks for the functional analysis demand condition with 4 individuals who had been diagnosed with autism. During the demand assessment, a therapist presented a variety of tasks, and observers measured problem behavior and compliance to identify demands associated with low levels of compliance or high levels of problem behavior (low-probability demands) and demands associated with high levels of compliance or low levels of problem behavior (high-probability demands). Results showed that clearer functional analysis outcomes were obtained for 3 of the 4 participants when low-probability rather than high-probability demands were used.

  5. Text Analysis: A Functional Linguistic Approach of News Introduction

    Institute of Scientific and Technical Information of China (English)

    刘锦凤

    2009-01-01

    The past several decades have witnessed a phenomenal growth in interest in text analysis, in which different kinds of approaches have been studied and applied in this field. This paper aims at analyzing the introduction of a cho-sen CNN News from a functional linguis.tic approach, which is mainly realized through cohesive means and textual infor-mation. The study shows that in written text, well-organized semantic cohesive means and textual information are of great significance for readers to follow the movement of an idea from one sentence to another. Therefore, functional approach plays a momentous role in the analysis of a text.

  6. An introduction with medical applications to functional data analysis

    DEFF Research Database (Denmark)

    Sørensen, Helle; Goldsmith, Jeff; Sangalli, Laura M

    2013-01-01

    Functional data are data that can be represented by suitable functions, such as curves (potentially multi-dimensional) or surfaces. This paper gives an introduction to some basic but important techniques for the analysis of such data, and we apply the techniques to two datasets from biomedicine....... One dataset is about white matter structures in the brain in multiple sclerosis patients; the other dataset is about three-dimensional vascular geometries collected for the study of cerebral aneurysms. The techniques described are smoothing, alignment, principal component analysis, and regression....

  7. Generating function approach to reliability analysis of structural systems

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The generating function approach is an important tool for performance assessment in multi-state systems. Aiming at strength reliability analysis of structural systems, generating function approach is introduced and developed. Static reliability models of statically determinate, indeterminate systems and fatigue reliability models are built by constructing special generating functions, which are used to describe probability distributions of strength (resistance), stress (load) and fatigue life, by defining composite operators of generating functions and performance structure functions thereof. When composition operators are executed, computational costs can be reduced by a big margin by means of collecting like terms. The results of theoretical analysis and numerical simulation show that the generating function approach can be widely used for probability modeling of large complex systems with hierarchical structures due to the unified form, compact expression, computer program realizability and high universality. Because the new method considers twin loads giving rise to component failure dependency, it can provide a theoretical reference and act as a powerful tool for static, dynamic reliability analysis in civil engineering structures and mechanical equipment systems with multi-mode damage coupling.

  8. Functional Parallel Factor Analysis for Functions of One- and Two-dimensional Arguments.

    Science.gov (United States)

    Choi, Ji Yeh; Hwang, Heungsun; Timmerman, Marieke E

    2017-02-14

    Parallel factor analysis (PARAFAC) is a useful multivariate method for decomposing three-way data that consist of three different types of entities simultaneously. This method estimates trilinear components, each of which is a low-dimensional representation of a set of entities, often called a mode, to explain the maximum variance of the data. Functional PARAFAC permits the entities in different modes to be smooth functions or curves, varying over a continuum, rather than a collection of unconnected responses. The existing functional PARAFAC methods handle functions of a one-dimensional argument (e.g., time) only. In this paper, we propose a new extension of functional PARAFAC for handling three-way data whose responses are sequenced along both a two-dimensional domain (e.g., a plane with x- and y-axis coordinates) and a one-dimensional argument. Technically, the proposed method combines PARAFAC with basis function expansion approximations, using a set of piecewise quadratic finite element basis functions for estimating two-dimensional smooth functions and a set of one-dimensional basis functions for estimating one-dimensional smooth functions. In a simulation study, the proposed method appeared to outperform the conventional PARAFAC. We apply the method to EEG data to demonstrate its empirical usefulness.

  9. Functional analysis of candidate ABC transporter proteins for sitosterol transport

    DEFF Research Database (Denmark)

    Albrecht, C; Elliott, J I; Sardini, A;

    2002-01-01

    implicated in lipid movement and expressed in tissues with a role in sterol synthesis and absorption, might also be involved in sitosterol transport. Transport by the multidrug resistance P-glycoprotein (P-gp; Abcb1), the multidrug resistance-associated protein (Mrp1; Abcc1), the breast cancer resistance...... the absorption of sitosterol and related molecules in the intestine by pumping them back into the lumen. Although mutations altering ABCG5 and ABCG8 are found in affected patients, no functional demonstration of sitosterol transport has been achieved. In this study, we investigated whether other ABC transporters...

  10. Intelligence, classroom behavior, and academic achievement in children at high and low risk for psychopathology: a structural equation analysis.

    Science.gov (United States)

    Worland, J; Weeks, D G; Janes, C L; Strock, B D

    1984-09-01

    The intelligence, academic achievement, and classroom behavior of 158 children were assessed in a sample that is being followed longitudinally. The sample included children at high risk for mental disorder by virtue of having a parent with a psychiatric diagnosis of schizophrenia or affective disorder, children at moderate risk, and children at low risk. A series of path analyses indicated that in this sample (1) classroom behavior was more likely an affect that a cause of academic achievement, and (2) the influence of parental psychopathology on classroom behavior was mediated by a child's intelligence and academic achievement. We were unable to substantiate an unmediated causal link between parental psychopathology and children's academic achievement or classroom behavior.

  11. Using confirmatory factor analysis to understand executive control in preschool children: sources of variation in emergent mathematic achievement.

    Science.gov (United States)

    Bull, Rebecca; Espy, Kimberly Andrews; Wiebe, Sandra A; Sheffield, Tiffany D; Nelson, Jennifer Mize

    2011-07-01

    Latent variable modeling methods have demonstrated utility for understanding the structure of executive control (EC) across development. These methods are utilized to better characterize the relation between EC and mathematics achievement in the preschool period, and to understand contributing sources of individual variation. Using the sample and battery of laboratory tasks described in Wiebe, Espy and Charak (2008), latent EC was related strongly to emergent mathematics achievement in preschool, and was robust after controlling for crystallized intellectual skills. The relation between crystallized skills and emergent mathematics differed between girls and boys, although the predictive association between EC and mathematics did not. Two dimensions of the child 's social environment contributed to mathematics achievement: social network support through its relation to EC and environmental stressors through its relation with crystallized skills. These findings underscore the need to examine the dimensions, mechanisms, and individual pathways that influence the development of early competence in basic cognitive processes that underpin early academic achievement.

  12. Bending analysis of a functionally graded piezoelectric cantilever beam

    Institute of Scientific and Technical Information of China (English)

    YU Tao; ZHONG Zheng

    2007-01-01

    A new analysis based on Airy stress function method is presented for a functionally graded piezoelectric material cantilever beam.Assuming that the mechanical and electric properties of the material have the same variations along the thickness direction,a two-dimensional plane elasticity solution is obtained for the coupling electroelastic fields of the beam under different loadings.This solution will be useful in analyzing FGPM beam with arbitrary variations of material properties.The influences of the functionally graded material properties on the structural response of the beam subjected to different loads are also studied through numerical examples.

  13. Bending analysis of a functionally graded piezoelectric cantilever beam

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A new analysis based on Airy stress function method is presented for a functionally graded piezoelectric material cantilever beam. Assuming that the mechanical and electric properties of the material have the same variations along the thickness direction, a two-dimensional plane elasticity solution is obtained for the coupling electroelastic fields of the beam under different loadings. This solution will be useful in analyzing FGPM beam with arbitrary variations of material properties. The influences of the functionally graded material properties on the structural response of the beam subjected to different loads are also studied through numerical examples.

  14. Current peptidomics: applications, purification, identification, quantification, and functional analysis.

    Science.gov (United States)

    Dallas, David C; Guerrero, Andres; Parker, Evan A; Robinson, Randall C; Gan, Junai; German, J Bruce; Barile, Daniela; Lebrilla, Carlito B

    2015-03-01

    Peptidomics is an emerging field branching from proteomics that targets endogenously produced protein fragments. Endogenous peptides are often functional within the body-and can be both beneficial and detrimental. This review covers the use of peptidomics in understanding digestion, and identifying functional peptides and biomarkers. Various techniques for peptide and glycopeptide extraction, both at analytical and preparative scales, and available options for peptide detection with MS are discussed. Current algorithms for peptide sequence determination, and both analytical and computational techniques for quantification are compared. Techniques for statistical analysis, sequence mapping, enzyme prediction, and peptide function, and structure prediction are explored.

  15. A Functional Complexity Framework for the Analysis of Telecommunication Networks

    CERN Document Server

    Dzaferagic, Merim; Macaluso, Irene; Marchetti, Nicola

    2016-01-01

    The rapid evolution of network services demands new paradigms for studying and designing networks. In order to understand the underlying mechanisms that provide network functions, we propose a framework which enables the functional analysis of telecommunication networks. This framework allows us to isolate and analyse a network function as a complex system. We propose functional topologies to visualise the relationships between system entities and enable the systematic study of interactions between them. We also define a complexity metric $C_F$ (functional complexity) which quantifies the variety of structural patterns and roles of nodes in the topology. This complexity metric provides a wholly new approach to study the operation of telecommunication networks. We study the relationship between $C_F$ and different graph structures by analysing graph theory metrics in order to recognize complex organisations. $C_F$ is equal to zero for both a full mesh topology and a disconnected topology. We show that complexi...

  16. Four Layered Approach to Non-Functional Requirements Analysis

    CERN Document Server

    Rao, A Ananda

    2012-01-01

    Identification of non-functional requirements is important for successful development and deployment of the software product. The acceptance of the software product by the customer depends on the non-functional requirements which are incorporated in the software. For this, we need to identify all the non-functional requirements required by all stakeholders. In the literature not many approaches are available for this purpose. Hence, we have proposed a four layered analysis approach for identification of non-functional requirements. The proposed layered approach has many advantages over non-layered approach. As part of this approach some rules are also proposed to be used in each layer. The approach is applied successfully on two case studies. The identified non-functional requirements are validated using a check list and in addition the completeness of the identified non-requirements is computed using a metric.

  17. Fractals and spectra related to fourier analysis and function spaces

    CERN Document Server

    Triebel, Hans

    1997-01-01

    Fractals and Spectra Hans Triebel This book deals with the symbiotic relationship between the theory of function spaces, fractal geometry, and spectral theory of (fractal) pseudodifferential operators as it has emerged quite recently. Atomic and quarkonial (subatomic) decompositions in scalar and vector valued function spaces on the euclidean n-space pave the way to study properties (compact embeddings, entropy numbers) of function spaces on and of fractals. On this basis, distributions of eigenvalues of fractal (pseudo)differential operators are investigated. Diverse versions of fractal drums are played. The book is directed to mathematicians interested in functional analysis, the theory of function spaces, fractal geometry, partial and pseudodifferential operators, and, in particular, in how these domains are interrelated. ------ It is worth mentioning that there is virtually no literature on this topic and hence the most of the presented material is published here the first time. - Zentralblatt MATH (…) ...

  18. Achieving consensus in robot swarms design and analysis of strategies for the best-of-n problem

    CERN Document Server

    Valentini, Gabriele

    2017-01-01

    This book focuses on the design and analysis of collective decision-making strategies for the best-of-n problem. After providing a formalization of the structure of the best-of-n problem supported by a comprehensive survey of the swarm robotics literature, it introduces the functioning of a collective decision-making strategy and identifies a set of mechanisms that are essential for a strategy to solve the best-of-n problem. The best-of-n problem is an abstraction that captures the frequent requirement of a robot swarm to choose one option from of a finite set when optimizing benefits and costs. The book leverages the identification of these mechanisms to develop a modular and model-driven methodology to design collective decision-making strategies and to analyze their performance at different level of abstractions. Lastly, the author provides a series of case studies in which the proposed methodology is used to design different strategies, using robot experiments to show how the designed strategies can b...

  19. Social Media’s Function in Organizations: A Functional Analysis Approach

    Directory of Open Access Journals (Sweden)

    Amy Reitz

    2012-12-01

    Full Text Available System theorists believe that organizations that function as an open system have a greater chance of survival than organizations that function as a closed system due to the exchange of inputs and outputs between the organization and its publics. Public relations researchers have proposed adopting a dialogic approach to public relations where interaction between the organization and its publics are mutual, which is the underpinning to an open systems approach. This paper posits that organizations can function within an open systems approach to public relations by employing social media. Adoption of a functional approach is a fruitful way to look at the social functions various social media serve in the system of organizations and their publics. Research has considered the gratifications publics receive from social media; however, limited research has considered what social media do for the organization-public relationship system. It has been argued that organizations also have psychological and social motivations; therefore, applying a functional analysis approach might be a good of way determining what functions social media serve in the organization-public relationship system. Four functions are proposed in which social media may serve the system: maintenance of organizational identity, opportunity to build relationships with publics, ability to control issues management, and the chance to promote social corporate responsibility. Understanding social media’s role in the system can help practitioners identify the functions that may contribute to an open systems approach to public relations and ultimately an organization’s survival.

  20. The Maslov index in weak symplectic functional analysis

    CERN Document Server

    Booss-Bavnbek, Bernhelm

    2013-01-01

    We recall the Chernoff-Marsden definition of weak symplectic structure and give a rigorous treatment of the functional analysis and geometry of weak symplectic Banach spaces. We define the Maslov index of a continuous path of Fredholm pairs of Lagrangian subspaces in continuously varying Banach spaces. We derive basic properties of this Maslov index and emphasize the new features appearing.

  1. Nonlinear boundary value problem for biregular functions in Clifford analysis

    Institute of Scientific and Technical Information of China (English)

    黄沙

    1996-01-01

    The biregular function in Clifford analysis is discussed. Plemelj’s formula is obtained andnonlinear boundary value problem: is considered. Applying the methodof integral equations and Schauder fixed-point theorem, the existence of solution for the above problem is proved.

  2. Semen analysis and sperm function tests: How much to test?

    Directory of Open Access Journals (Sweden)

    S S Vasan

    2011-01-01

    Full Text Available Semen analysis as an integral part of infertility investigations is taken as a surrogate measure for male fecundity in clinical andrology, male fertility, and pregnancy risk assessments. Clearly, laboratory seminology is still very much in its infancy. In as much as the creation of a conventional semen profile will always represent the foundations of male fertility evaluation, the 5th edition of the World Health Organization (WHO manual is a definitive statement on how such assessments should be carried out and how the quality should be controlled. A major advance in this new edition of the WHO manual, resolving the most salient critique of previous editions, is the development of the first well-defined reference ranges for semen analysis based on the analysis of over 1900 recent fathers. The methodology used in the assessment of the usual variables in semen analysis is described, as are many of the less common, but very valuable, sperm function tests. Sperm function testing is used to determine if the sperm have the biologic capacity to perform the tasks necessary to reach and fertilize ova and ultimately result in live births. A variety of tests are available to evaluate different aspects of these functions. To accurately use these functional assays, the clinician must understand what the tests measure, what the indications are for the assays, and how to interpret the results to direct further testing or patient management.

  3. Role of Cognition and Affect in a Functional Behavioral Analysis.

    Science.gov (United States)

    Nichols, Polly

    2000-01-01

    This article attempts to present a multidimensional perspective of functional behavioral analysis that will lead to psychoeducational interventions in which students with emotional/behavioral disorders are taught to think clearly, solve problems, and self-regulate the intensity of their emotions. (Contains references.) (Author/DB)

  4. Functional Analysis and Treatment of Noncompliance by Preschool Children

    OpenAIRE

    Wilder, David A; Harris, Carelle; Reagan, Renee; Rasey, Amy

    2007-01-01

    A functional analysis showed that noncompliance occurred most often for 2 preschoolers when it resulted in termination of a preferred activity, suggesting that noncompliance was maintained by positive reinforcement. A differential reinforcement procedure, which involved contingent access to coupons that could be exchanged for uninterrupted access to the activity maintaining noncompliance, was successful in increasing compliance for both children.

  5. Functional Analysis and Treatment of Noncompliance by Preschool Children

    Science.gov (United States)

    Wilder, David A.; Harris, Carelle; Reagan, Renee; Rasey, Amy

    2007-01-01

    A functional analysis showed that noncompliance occurred most often for 2 preschoolers when it resulted in termination of a preferred activity, suggesting that noncompliance was maintained by positive reinforcement. A differential reinforcement procedure, which involved contingent access to coupons that could be exchanged for uninterrupted access…

  6. Pomeron-Odderon Interactions: A Functional RG Flow Analysis

    CERN Document Server

    Vacca, Gian Paolo

    2016-01-01

    In the quest for an effective field theory which could help to understand some non perturbative feature of the QCD in the Regge limit, we consider a Reggeon Field Theory (RFT) for both Pomeron and Odderon interactions and perform an analysys of the critical theory using functional renormalization group techniques, unveiling a novel symmetry structure.

  7. Large-scale data analysis using the Wigner function

    Science.gov (United States)

    Earnshaw, R. A.; Lei, C.; Li, J.; Mugassabi, S.; Vourdas, A.

    2012-04-01

    Large-scale data are analysed using the Wigner function. It is shown that the 'frequency variable' provides important information, which is lost with other techniques. The method is applied to 'sentiment analysis' in data from social networks and also to financial data.

  8. ON RUBIN'S HARMONIC ANALYSIS AND ITS RELATED POSITIVE DEFINITE FUNCTIONS

    Institute of Scientific and Technical Information of China (English)

    Néji Bettaibi; Kamel Mezlini; Moufida El Guénichi

    2012-01-01

    In this paper,a new formulation of the Rubin's q-translation is given,which leads to a reliable q-harmonic analysis.Next,related q-positive definite functions are introduced and studied,and a Bochner's theorem is proved.

  9. Functional MRI experiments : acquisition, analysis and interpretation of data

    NARCIS (Netherlands)

    Ramsey, NF; Hoogduin, H; Jansma, JM

    2002-01-01

    Functional MRI is widely used to address basic and clinical neuroscience questions. In the key domains of fMRI experiments, i.e. acquisition, processing and analysis, and interpretation of data, developments are ongoing. The main issues are sensitivity for changes in fMRI signal that are associated

  10. Lexical, Functional Grammar Analysis of Korean Complex Predicates.

    Science.gov (United States)

    Kim, Hee-Seob

    The structure of complementation in complex predicates in Korean has attracted configurational analysis. Using a lexical functional grammar (LFG) framework, this paper examines the structure of complementation in complex predicates. The term "predicate" in this context is used to describe both verbs and adjectives that are assumed to…

  11. Epistasis analysis for quantitative traits by functional regression model.

    Science.gov (United States)

    Zhang, Futao; Boerwinkle, Eric; Xiong, Momiao

    2014-06-01

    The critical barrier in interaction analysis for rare variants is that most traditional statistical methods for testing interactions were originally designed for testing the interaction between common variants and are difficult to apply to rare variants because of their prohibitive computational time and poor ability. The great challenges for successful detection of interactions with next-generation sequencing (NGS) data are (1) lack of methods for interaction analysis with rare variants, (2) severe multiple testing, and (3) time-consuming computations. To meet these challenges, we shift the paradigm of interaction analysis between two loci to interaction analysis between two sets of loci or genomic regions and collectively test interactions between all possible pairs of SNPs within two genomic regions. In other words, we take a genome region as a basic unit of interaction analysis and use high-dimensional data reduction and functional data analysis techniques to develop a novel functional regression model to collectively test interactions between all possible pairs of single nucleotide polymorphisms (SNPs) within two genome regions. By intensive simulations, we demonstrate that the functional regression models for interaction analysis of the quantitative trait have the correct type 1 error rates and a much better ability to detect interactions than the current pairwise interaction analysis. The proposed method was applied to exome sequence data from the NHLBI's Exome Sequencing Project (ESP) and CHARGE-S study. We discovered 27 pairs of genes showing significant interactions after applying the Bonferroni correction (P-values < 4.58 × 10(-10)) in the ESP, and 11 were replicated in the CHARGE-S study.

  12. Relevance of Item Analysis in Standardizing an Achievement Test in Teaching of Physical Science in B.Ed Syllabus

    Science.gov (United States)

    Marie, S. Maria Josephine Arokia; Edannur, Sreekala

    2015-01-01

    This paper focused on the analysis of test items constructed in the paper of teaching Physical Science for B.Ed. class. It involved the analysis of difficulty level and discrimination power of each test item. Item analysis allows selecting or omitting items from the test, but more importantly item analysis is a tool to help the item writer improve…

  13. Stochastic processes and functional analysis a volume of recent advances in honor of M. M. Rao

    CERN Document Server

    Krinik, Alan C

    2004-01-01

    This extraordinary compilation is an expansion of the recent American Mathematical Society Special Session celebrating M. M. Rao's distinguished career and includes most of the presented papers as well as ancillary contributions from session invitees. This book shows the effectiveness of abstract analysis for solving fundamental problems of stochastic theory, specifically the use of functional analytic methods for elucidating stochastic processes, as made manifest in M. M. Rao's prolific research achievements. Featuring a biography of M. M. Rao, a complete bibliography of his published works,

  14. A Long-Gap Peripheral Nerve Injury Therapy Using Human Skeletal Muscle-Derived Stem Cells (Sk-SCs): An Achievement of Significant Morphological, Numerical and Functional Recovery.

    Science.gov (United States)

    Tamaki, Tetsuro; Hirata, Maki; Nakajima, Nobuyuki; Saito, Kosuke; Hashimoto, Hiroyuki; Soeda, Shuichi; Uchiyama, Yoshiyasu; Watanabe, Masahiko

    2016-01-01

    Losses in vital functions of the somatic motor and sensory nervous system are induced by severe long-gap peripheral nerve transection injury. In such cases, autologous nerve grafts are the gold standard treatment, despite the unavoidable sacrifice of other healthy functions, whereas the prognosis is not always favorable. Here, we use human skeletal muscle-derived stem cells (Sk-SCs) to reconstitute the function after long nerve-gap injury. Muscles samples were obtained from the amputated legs from 9 patients following unforeseen accidents. The Sk-SCs were isolated using conditioned collagenase solution, and sorted as CD34+/45- (Sk-34) and CD34-/45-/29+ (Sk-DN/29+) cells. Cells were separately cultured/expanded under optimal conditions for 2 weeks, then injected into the athymic nude mice sciatic nerve long-gap model (7-mm) bridging an acellular conduit. After 8-12 weeks, active cell engraftment was observed only in the Sk-34 cell transplanted group, showing preferential differentiation into Schwann cells and perineurial/endoneurial cells, as well as formation of the myelin sheath and perineurium/endoneurium surrounding regenerated axons, resulted in 87% of numerical recovery. Differentiation into vascular cell lineage (pericyte and endothelial cells) were also observed. A significant tetanic tension recovery (over 90%) of downstream muscles following electrical stimulation of the sciatic nerve (at upper portion of the gap) was also achieved. In contrast, Sk-DN/29+ cells were completely eliminated during the first 4 weeks, but relatively higher numerical (83% vs. 41% in axon) and functional (80% vs. 60% in tetanus) recovery than control were observed. Noteworthy, significant increase in the formation of vascular networks in the conduit during the early stage (first 2 weeks) of recovery was observed in both groups with the expression of key factors (mRNA and protein levels), suggesting the paracrine effects to angiogenesis. These results suggested that the human Sk

  15. The Effect of Prior Experience with Computers, Statistical Self-Efficacy, and Computer Anxiety on Students' Achievement in an Introductory Statistics Course: A Partial Least Squares Path Analysis

    Science.gov (United States)

    Abd-El-Fattah, Sabry M.

    2005-01-01

    A Partial Least Squares Path Analysis technique was used to test the effect of students' prior experience with computers, statistical self-efficacy, and computer anxiety on their achievement in an introductory statistics course. Computer Anxiety Rating Scale and Current Statistics Self-Efficacy Scale were administered to a sample of 64 first-year…

  16. Competence in Mathematics and Academic Achievement: An Analysis of Enrollees in the Bachelor of Science in Actuarial Science Program

    Science.gov (United States)

    Wamala, Robert; Maswere, Dyson W.; Mwanga, Yeko

    2013-01-01

    This study investigates the role of prior grounding attained in mathematics in predicting the academic achievement of enrollees in Bachelor of Science in Actuarial Science (BSAS). The investigation is based on administrative records of 240 BSAS enrollees at Makerere University, School of Statistics and Planning in the 2007-2009 cohorts. Students'…

  17. Cultural Transition and Academic Achievement of Students from Ethnic Minority Backgrounds: A Content Analysis of Empirical Research on Acculturation

    Science.gov (United States)

    Makarova, Elena; Birman, Dina

    2015-01-01

    Background: The achievement gap between immigrant and non-immigrant students that has been identified in most OECD countries and the considerable educational dropout rate among students from ethnic minority backgrounds in some countries have become serious challenges for national educational systems. The educational underachievement of young…

  18. An Analysis of the Relationships between Taiwanese Eighth and Fourth Graders' Motivational Beliefs and Science Achievement in TIMSS 2011

    Science.gov (United States)

    Liou, Pey-Yan; Liu, Eric Zhi-Feng

    2015-01-01

    The purpose of this study is to examine the issues of students' motivational beliefs in science learning and their relations with science achievement. Data of Taiwanese fourth and eighth graders from the Trends in International Mathematics and Science Study 2011 were examined. Students' self-concept and intrinsic interest as motivational beliefs,…

  19. An Analysis of Certain Interpersonal Aspects of the Home and School in Low Socioeconomic Areas Relating to Student Achievement.

    Science.gov (United States)

    Sommerville, Joseph C.

    This article summarizes an investigation of factors manifested by 6th grade students in four Detroit metropolitan area schools who achieved on the Iowa Test of Basic Skills at levels significantly above and below the average. The study sample consisted of 80 students with scores divided equally above and below the average. Instruments measured…

  20. Behavioral Engagement and Reading Achievement in Elementary-School-Age Children: A Longitudinal Cross-Lagged Analysis

    Science.gov (United States)

    Guo, Ying; Sun, Shuyan; Breit-Smith, Allison; Morrison, Frederick J.; Connor, Carol McDonald

    2015-01-01

    Using data from the National Institute of Child Health and Human Development's Study of Early Child Care and Youth Development, this study examined the cross-lagged relations between behavioral engagement and reading achievement in elementary school and whether these cross-lagged relations differed between low-socioeconomic status (SES) and mid-…

  1. The Effectiveness of Educational Technology Applications for Enhancing Mathematics Achievement in K-12 Classrooms: A Meta-Analysis

    Science.gov (United States)

    Cheung, Alan C. K.; Slavin, Robert E.

    2013-01-01

    The present review examines research on the effects of educational technology applications on mathematics achievement in K-12 classrooms. Unlike previous reviews, this review applies consistent inclusion standards to focus on studies that met high methodological standards. In addition, methodological and substantive features of the studies are…

  2. Prospective analysis of LDL-C goal achievement and self-reported medication adherence among statin users in primary care.

    LENUS (Irish Health Repository)

    Bermingham, Margaret

    2011-09-01

    Improvements in the control of LDL-C levels have occurred in the past decade due to the introduction of increasingly potent statins, such as atorvastatin and rosuvastatin. Many patients, however, do not achieve their LDL-C goals, which presents a practical dilemma for clinicians and highlights the need to identify adherence problems in a clinically relevant manner.

  3. Influences on Academic Achievement Across High and Low Income Countries: A Re-Analysis of IEA Data.

    Science.gov (United States)

    Heyneman, S.; Loxley, W.

    Previous international studies of science achievement put the data through a process of winnowing to decide which variables to keep in the final regressions. Variables were allowed to enter the final regressions if they met a minimum beta coefficient criterion of 0.05 averaged across rich and poor countries alike. The criterion was an average…

  4. A Comparative Analysis of Single-Sex Schools in Terms of Achievement in Reading and Math and Student Attendance

    Science.gov (United States)

    Brathwaite, Debra Ann

    2010-01-01

    Single-sex education is a reform initiative that is taking root in the United States and in many countries around the world as a possible solution to closing the racial, achievement, and gender gaps that have emerged where minority students lag behind their White counterparts and boys are falling behind girls academically. Although there have been…

  5. The Relation between Self-Regulated Learning and Academic Achievement across Childhood and Adolescence: A Meta-Analysis

    Science.gov (United States)

    Dent, Amy L.; Koenka, Alison C.

    2016-01-01

    This research synthesis explores how academic achievement relates to two main components of self-regulated learning for students in elementary and secondary school. Two meta-analyses integrated previous findings on (1) the defining metacognitive processes of self-regulated learning and (2) students' use of cognitive strategies. Overall…

  6. Cultural Transition and Academic Achievement of Students from Ethnic Minority Backgrounds: A Content Analysis of Empirical Research on Acculturation

    Science.gov (United States)

    Makarova, Elena; Birman, Dina

    2015-01-01

    Background: The achievement gap between immigrant and non-immigrant students that has been identified in most OECD countries and the considerable educational dropout rate among students from ethnic minority backgrounds in some countries have become serious challenges for national educational systems. The educational underachievement of young…

  7. Social Capital in Schools: A Conceptual and Empirical Analysis of the Equity of Its Distribution and Relation to Academic Achievement

    Science.gov (United States)

    Salloum, Serena J.; Goddard, Roger D.; Larsen, Ross

    2017-01-01

    Background: Schools face pressure to promote equitable student outcomes as the achievement gap continues to persist. The authors examine different ways in which social capital has been conceptualized as well as prior theory and research on its formation and consequences. While some theoretical and empirical work conceptualizes social capital as a…

  8. Science Learning: A Path Analysis of Its Links with Reading Comprehension, Question-Asking in Class and Science Achievement

    Science.gov (United States)

    Cano, Francisco; García, Ángela; Berbén, A. B. G.; Justicia, Fernando

    2014-01-01

    The purpose of this research was to build and test a conceptual model of the complex interrelationships between students' learning in science (learning approaches and self-regulation), their reading comprehension, question-asking in class and science achievement. These variables were measured by means of a test and a series of questionnaires…

  9. Using Confirmatory Factor Analysis to Understand Executive Control in Preschool Children: Sources of Variation in Emergent Mathematic Achievement

    Science.gov (United States)

    Bull, Rebecca; Espy, Kimberly Andrews; Wiebe, Sandra A.; Sheffield, Tiffany D.; Nelson, Jennifer Mize

    2011-01-01

    Latent variable modeling methods have demonstrated utility for understanding the structure of executive control (EC) across development. These methods are utilized to better characterize the relation between EC and mathematics achievement in the preschool period, and to understand contributing sources of individual variation. Using the sample and…

  10. A Multilevel Analysis of the Role of School Quality and Family Background on Students' Mathematics Achievement in the Middle East

    Science.gov (United States)

    Kareshki, Hossein; Hajinezhad, Zahra

    2014-01-01

    The purpose of the present study is investigating the correlation between school quality and family socioeconomic background and students' mathematics achievement in the Middle East. The countries in comparison are UAE, Syria, Qatar, Iran, Saudi Arabia, Oman, Lebanon, Jordan, and Bahrain. The study utilized data from IEA's Trends in International…

  11. An Analysis of the Relationship between Principal Employment Interview Scores and the Achievement Scores of Students with Specific Learning Disabilities

    Science.gov (United States)

    Ostmeyer, Susan S.

    2012-01-01

    The primary purpose of this study was to examine the relationship between five of ISSLC's 2008 leadership standards as measured by a standardized employment interview (ICIS Principal) and the achievement of students with specific learning disabilities in core areas of instruction. Findings did not support the rejection of the null hypothesis.…

  12. Teaching Quality in Math Class: The Development of a Scale and the Analysis of Its Relationship with Engagement and Achievement

    Directory of Open Access Journals (Sweden)

    Jaime Leon

    2017-06-01

    Full Text Available Math achievement and engagement declines in secondary education; therefore, educators are faced with the challenge of engaging students to avoid school failure. Within self-determination theory, we address the need to assess comprehensively student perceptions of teaching quality that predict engagement and achievement. In study one we tested, in a sample of 548 high school students, a preliminary version of a scale to assess nine factors: teaching for relevance, acknowledge negative feelings, participation encouragement, controlling language, optimal challenge, focus on the process, class structure, positive feedback, and caring. In the second study, we analyzed the scale’s reliability and validity in a sample of 1555 high school students. The scale showed evidence of reliability, and with regard to criterion validity, at the classroom level, teaching quality was a predictor of behavioral engagement, and higher grades were observed in classes where students, as a whole, displayed more behavioral engagement. At the within level, behavioral engagement was associated with achievement. We not only provide a reliable and valid method to assess teaching quality, but also a method to design interventions, these could be designed based on the scale items to encourage students to persist and display more engagement on school duties, which in turn bolsters student achievement.

  13. Teaching Quality in Math Class: The Development of a Scale and the Analysis of Its Relationship with Engagement and Achievement

    Science.gov (United States)

    Leon, Jaime; Medina-Garrido, Elena; Núñez, Juan L.

    2017-01-01

    Math achievement and engagement declines in secondary education; therefore, educators are faced with the challenge of engaging students to avoid school failure. Within self-determination theory, we address the need to assess comprehensively student perceptions of teaching quality that predict engagement and achievement. In study one we tested, in a sample of 548 high school students, a preliminary version of a scale to assess nine factors: teaching for relevance, acknowledge negative feelings, participation encouragement, controlling language, optimal challenge, focus on the process, class structure, positive feedback, and caring. In the second study, we analyzed the scale’s reliability and validity in a sample of 1555 high school students. The scale showed evidence of reliability, and with regard to criterion validity, at the classroom level, teaching quality was a predictor of behavioral engagement, and higher grades were observed in classes where students, as a whole, displayed more behavioral engagement. At the within level, behavioral engagement was associated with achievement. We not only provide a reliable and valid method to assess teaching quality, but also a method to design interventions, these could be designed based on the scale items to encourage students to persist and display more engagement on school duties, which in turn bolsters student achievement. PMID:28701964

  14. Religiosity, Religious Schools, and Their Relationship with the Achievement Gap: A Research Synthesis and Meta-Analysis

    Science.gov (United States)

    Jeynes, William H.

    2010-01-01

    A research synthesis was conducted including three meta analyses, a review of the relevant literature, and supplemental analyses examining the relationship between personal faith and the reduction of the achievement gap. Personal faith included belief and adherence to any religion. The results of the three meta-analyses indicated that: (a)…

  15. Science Learning: A Path Analysis of Its Links with Reading Comprehension, Question-Asking in Class and Science Achievement

    Science.gov (United States)

    Cano, Francisco; García, Ángela; Berbén, A. B. G.; Justicia, Fernando

    2014-01-01

    The purpose of this research was to build and test a conceptual model of the complex interrelationships between students' learning in science (learning approaches and self-regulation), their reading comprehension, question-asking in class and science achievement. These variables were measured by means of a test and a series of questionnaires…

  16. A Mixed-Method Analysis of the Alignment of Title I Achieving Schools' Professional Development to NCLB Professional Development Provisions

    Science.gov (United States)

    Quinn, Kerry

    2013-01-01

    The improvement of schools has been a central discussion among educators, legislators, and stakeholders, with professional development being acknowledged as a fundamental topic for the success of the education system. Studying the alignment of professional development programs provided at Title I Achieving schools to NCLB research based…

  17. Professional Learning Communities: An Analysis of Teacher Participation in a PLC and the Relationship with Student Academic Achievement

    Science.gov (United States)

    Aylsworth, Anthony James

    2012-01-01

    This study sought to compare teacher participation in a Professional Learning Community with the performance of their students. Student achievement data from multiple subject-alike groups were compared in a pre-and post-PLC format, using an independent, two-sample t-test. Overall, 10 PLCs from one high school in a suburban, Iowa setting were…

  18. Functional analysis of Bombyx Wnt1 during embryogenesis using the CRISPR/Cas9 system.

    Science.gov (United States)

    Zhang, Zhongjie; Aslam, Abu F M; Liu, Xiaojing; Li, Muwang; Huang, Yongping; Tan, Anjiang

    2015-08-01

    Recently established, custom-designed nuclease technologies such as the clustered regularly interspaced short palindromic repeat (CRISPR)-associated system provide attractive genome editing tools. Targeted gene mutagenesis using the CRISPR/Cas9 system has been achieved in several orders of insects. However, outside of studies on Drosophila melanogaster and the lepidopteron model insect Bombyx mori, little success has been reported, which is largely due to a lack of effective genetic manipulation tools that can be used in other insect orders. To create a simple and effective method of gene knockout analysis, especially for dissecting gene functioning during insect embryogenesis, we performed a functional analysis of the Bombyx Wnt1 (BmWnt1) gene using Cas9/sgRNA-mediated gene mutagenesis. The Wnt1 gene is required for embryonic patterning in various organisms, and its crucial roles during embryogenesis have been demonstrated in several insect orders. Direct injection of Cas9 mRNA and BmWnt1-specific sgRNA into Bombyx embryos induced a typical Wnt-deficient phenotype: injected embryos could not hatch and exhibited severe defects in body segmentation and pigmentation in a dose-dependent manner. Quantitative real-time PCR (qRT-PCR) analysis revealed that Hox genes were down-regulated after BmWnt1 depletion. Furthermore, large deletion, up to 18Kb, ware generated. The current study demonstrates that using the CRISPR/Cas9 system is a promising approach to achieve targeted gene mutagenesis during insect embryogenesis.

  19. Consolidity analysis for fully fuzzy functions, matrices, probability and statistics

    Directory of Open Access Journals (Sweden)

    Walaa Ibrahim Gabr

    2015-03-01

    Full Text Available The paper presents a comprehensive review of the know-how for developing the systems consolidity theory for modeling, analysis, optimization and design in fully fuzzy environment. The solving of systems consolidity theory included its development for handling new functions of different dimensionalities, fuzzy analytic geometry, fuzzy vector analysis, functions of fuzzy complex variables, ordinary differentiation of fuzzy functions and partial fraction of fuzzy polynomials. On the other hand, the handling of fuzzy matrices covered determinants of fuzzy matrices, the eigenvalues of fuzzy matrices, and solving least-squares fuzzy linear equations. The approach demonstrated to be also applicable in a systematic way in handling new fuzzy probabilistic and statistical problems. This included extending the conventional probabilistic and statistical analysis for handling fuzzy random data. Application also covered the consolidity of fuzzy optimization problems. Various numerical examples solved have demonstrated that the new consolidity concept is highly effective in solving in a compact form the propagation of fuzziness in linear, nonlinear, multivariable and dynamic problems with different types of complexities. Finally, it is demonstrated that the implementation of the suggested fuzzy mathematics can be easily embedded within normal mathematics through building special fuzzy functions library inside the computational Matlab Toolbox or using other similar software languages.

  20. Cocaine dependence and thalamic functional connectivity: a multivariate pattern analysis

    Directory of Open Access Journals (Sweden)

    Sheng Zhang

    2016-01-01

    Full Text Available Cocaine dependence is associated with deficits in cognitive control. Previous studies demonstrated that chronic cocaine use affects the activity and functional connectivity of the thalamus, a subcortical structure critical for cognitive functioning. However, the thalamus contains nuclei heterogeneous in functions, and it is not known how thalamic subregions contribute to cognitive dysfunctions in cocaine dependence. To address this issue, we used multivariate pattern analysis (MVPA to examine how functional connectivity of the thalamus distinguishes 100 cocaine-dependent participants (CD from 100 demographically matched healthy control individuals (HC. We characterized six task-related networks with independent component analysis of fMRI data of a stop signal task and employed MVPA to distinguish CD from HC on the basis of voxel-wise thalamic connectivity to the six independent components. In an unbiased model of distinct training and testing data, the analysis correctly classified 72% of subjects with leave-one-out cross-validation (p < 0.001, superior to comparison brain regions with similar voxel counts (p < 0.004, two-sample t test. Thalamic voxels that form the basis of classification aggregate in distinct subclusters, suggesting that connectivities of thalamic subnuclei distinguish CD from HC. Further, linear regressions provided suggestive evidence for a correlation of the thalamic connectivities with clinical variables and performance measures on the stop signal task. Together, these findings support thalamic circuit dysfunction in cognitive control as an important neural marker of cocaine dependence.