Large-scale manufacture and characterization of a lentiviral vector produced for clinical ex vivo gene therapy application.

Science.gov (United States)

Merten, Otto-Wilhelm; Charrier, Sabine; Laroudie, Nicolas; Fauchille, Sylvain; Dugué, Céline; Jenny, Christine; Audit, Muriel; Zanta-Boussif, Maria-Antonietta; Chautard, Hélène; Radrizzani, Marina; Vallanti, Giuliana; Naldini, Luigi; Noguiez-Hellin, Patricia; Galy, Anne

2011-03-01

From the perspective of a pilot clinical gene therapy trial for Wiskott-Aldrich syndrome (WAS), we implemented a process to produce a lentiviral vector under good manufacturing practices (GMP). The process is based on the transient transfection of 293T cells in Cell Factory stacks, scaled up to harvest 50 liters of viral stock per batch, followed by purification of the vesicular stomatitis virus glycoprotein-pseudotyped particles through several membrane-based and chromatographic steps. The process leads to a 200-fold volume concentration and an approximately 3-log reduction in protein and DNA contaminants. An average yield of 13% of infectious particles was obtained in six full-scale preparations. The final product contained low levels of contaminants such as simian virus 40 large T antigen or E1A sequences originating from producer cells. Titers as high as 2 × 10(9) infectious particles per milliliter were obtained, generating up to 6 × 10(11) infectious particles per batch. The purified WAS vector was biologically active, efficiently expressing the genetic insert in WAS protein-deficient B cell lines and transducing CD34(+) cells. The vector introduced 0.3-1 vector copy per cell on average in CD34(+) cells when used at the concentration of 10(8) infectious particles per milliliter, which is comparable to preclinical preparations. There was no evidence of cellular toxicity. These results show the implementation of large-scale GMP production, purification, and control of advanced HIV-1-derived lentiviral technology. Results obtained with the WAS vector provide the initial manufacturing and quality control benchmarking that should be helpful to further development and clinical applications.

Preservation of large yellow croaker (Pseudosciaena crocea) by Coagulin L1208, a novel bacteriocin produced by Bacillus coagulans L1208.

Science.gov (United States)

Fu, Linglin; Wang, Chong; Ruan, Xinming; Li, Gang; Zhao, Yu; Wang, Yanbo

2018-02-02

Large yellow croaker (Pseudosciaena crocea) is a cultivated fish of great economic importance and abundant nutritional value. However, due to its high protein and water contents, it is susceptible to decomposition, leading to considerable economic loss and adverse effects on consumer health. Here, we assessed the function of the bacterial strain Bacillus coagulans L1208 (Bcoa) in preserving large yellow croaker during storage at 4°C and found that Bcoa elongates the shelf-life significantly. Further investigations showed that Bcoa prolongs the storage time mainly by suppressing the growth of spoilage bacteria. Moreover, a novel bacteriocin, designated as Coagulin L1208 and produced by Bcoa, was purified and identified by N-terminal sequencing. Finally, the activity of Coagulin L1208 for suppressing spoilage bacteria during the preservation of large yellow croaker was assessed. Our results reveal the mechanism by which Bcoa aids the preservation of large yellow croaker and identify Coagulin L1208 as a potential novel antiseptic. Copyright © 2017 Elsevier B.V. All rights reserved.

Method of producing the arched surfaces of diaphragm rings for large containers, especially for prestressed-concrete pressure vessels of nuclear reactors

International Nuclear Information System (INIS)

Kumpf, H.

1976-01-01

In producing arched surfaces of diaphragm rings for large containers, especially for prestressed-concrete pressure vessels for nuclear power plants, it is of advantage to manufacture these directly on the construction site. According to the invention the, at first level, diaphragm ring is put on the predetermined place, sectionally pressed against and shaped by a shaping tool - with a profiled supporting ring as a counter-acting tool - and afterwards welded together with the annular wall sections of the large container along the shaped parts. The manufacture of single and double configurations of diaphragm rings is described. It is of advantage if shaping and mounting position coincide. (UWI) [de

Producing Distribution Maps for a Spatially-Explicit Ecosystem Model Using Large Monitoring and Environmental Databases and a Combination of Interpolation and Extrapolation

Directory of Open Access Journals (Sweden)

Arnaud Grüss

2018-01-01

Full Text Available To be able to simulate spatial patterns of predator-prey interactions, many spatially-explicit ecosystem modeling platforms, including Atlantis, need to be provided with distribution maps defining the annual or seasonal spatial distributions of functional groups and life stages. We developed a methodology combining extrapolation and interpolation of the predictions made by statistical habitat models to produce distribution maps for the fish and invertebrates represented in the Atlantis model of the Gulf of Mexico (GOM Large Marine Ecosystem (LME (“Atlantis-GOM”. This methodology consists of: (1 compiling a large monitoring database, gathering all the fisheries-independent and fisheries-dependent data collected in the northern (U.S. GOM since 2000; (2 compiling a large environmental database, storing all the environmental parameters known to influence the spatial distribution patterns of fish and invertebrates of the GOM; (3 fitting binomial generalized additive models (GAMs to the large monitoring and environmental databases, and geostatistical binomial generalized linear mixed models (GLMMs to the large monitoring database; and (4 employing GAM predictions to infer spatial distributions in the southern GOM, and GLMM predictions to infer spatial distributions in the U.S. GOM. Thus, our methodology allows for reasonable extrapolation in the southern GOM based on a large amount of monitoring and environmental data, and for interpolation in the U.S. GOM accurately reflecting the probability of encountering fish and invertebrates in that region. We used an iterative cross-validation procedure to validate GAMs. When a GAM did not pass the validation test, we employed a GAM for a related functional group/life stage to generate distribution maps for the southern GOM. In addition, no geostatistical GLMMs were fit for the functional groups and life stages whose depth, longitudinal and latitudinal ranges within the U.S. GOM are not entirely covered by

On numerical simulation of the global distribution of sulfate aerosol produced by a large volcanic eruption

Energy Technology Data Exchange (ETDEWEB)

Pudykiewicz, J.A.; Dastoor, A.P. [Atmospheric Environment Service, Quebec (Canada)

1994-12-31

Volcanic eruptions play an important role in the global sulfur cycle of the Earth`s atmosphere and can significantly perturb the global atmospheric chemistry. The large amount of sulfate aerosol produced by the oxidation of SO{sub 2} injected into the atmosphere during volcanic eruptions also has a relatively big influence on the radiative equilibrium of the Earth`s climatic system. The submicron particles of the sulfate aerosol reflect solar radiation more effectively than they trap radiation in the infrared range. The effect of this is observed as cooling of the Earth`s surface. The modification of the global radiation budget following volcanic eruption can subsequently cause significant fluctuations of atmospheric variables on a subclimatic scale. The resulting perturbation of weather patterns has been observed and well documented since the eruptions of Mt. Krakatau and Mt. Tambora. The impact of the sulfate aerosol from volcanic eruptions on the radiative equilibrium of the Earth`s atmosphere was also confirmed by the studies done with Global Circulation Models designed to simulate climate. The objective of the present paper is to present a simple and effective method to estimate the global distribution of the sulfate aerosol produced as a consequence of volcanic eruptions. In this study we will present results of the simulation of global distribution of sulfate aerosol from the eruption of Mt Pinatubo.

Progress of organic matter degradation and maturity of compost produced in a large-scale composting facility.

Science.gov (United States)

Nakasaki, Kiyohiko; Marui, Taketoshi

2011-06-01

To monitor the progress of organic matter degradation in a large-scale composting facility, the percentage of organic matter degradation was determined by measuring CO(2) evolution during recomposting of compost samples withdrawn from the facility. The percentage of organic matter degradation was calculated as the ratio of the amount of CO(2) evolved from compost raw material to that evolved from each sample during recomposting in the laboratory composting apparatus. It was assumed that the difference in the cumulative emission of CO(2) between the compost raw material and a sample corresponds to the amount of CO( 2) evolved from the sample in the composting facility. Using this method, the changes in organic matter degradation during composting in practical large-scale composting facilities were estimated and it was found that the percentage of organic matter degradation increased more vigorously in the earlier stages than in the later stages of composting. The percentage of organic matter degradation finally reached 78 and 55% for the compost produced from garbage-animal manure mixture and distillery waste (shochu residue), respectively. It was thus ascertained that organic matter degradation progressed well in both composting facilities. Furthermore, by performing a plant growth assay, it was observed that the compost products of both the facilities did not inhibit seed germination and thus were useful in promoting plant growth.

Coincident detection of electrons ejected at large angles and target recoil ions produced in multiply ionizing collisions for the 1-MeV/u Oq++Ar collision system

International Nuclear Information System (INIS)

Gaither III, C.C.; Breinig, M.; Berryman, J.W.; Hasson, B.F.; Richards, J.D.; Price, K.

1993-01-01

The angular distributions of energetic electrons ejected at angles between 45 degree and 135 degree with respect to the incident-beam direction have been measured in coincidence with the charge states of the target recoil ions produced in multiply ionizing collisions for the 1-MeV/u O q+ (q=4,7)+Ar collision systems. These measurements have been made for ∼179-, ∼345-, and ∼505-eV electrons. Additionally, the energy distributions of electrons ejected into specific angular regions have been measured. Ar LMM satellite Auger electrons appear as a peak in the energy spectrum of electrons ejected at all large angles. The center of this peak is found at an electron energy of ∼179 eV. Electrons with ∼179 eV energy, ejected at large angles, are preferentially produced in coincidence with recoil ions of charge state 4+. Electrons with ∼345 eV energy and ∼505 eV energy ejected at large angles are preferentially produced in coincidence with recoil ions of charge state 3+. The angular distributions for these electrons are strongly peaked in the forward direction; essentially no electrons are observed at angles larger than 90 degree. These results are consistent with the dominant production mechanism for energetic electrons ejected at large angles being a binary-encounter process. Differential cross sections have been calculated from these angular distributions. They are on the order of 10 -21 cm 2 /(eV sr)

Screening and characterization of Lactobacillus strains producing large amounts of exopolysaccharides

NARCIS (Netherlands)

Geel-Schutten, G.H. van; Flesch, F.; Brink, B. ten; Smith, M.R.; Dijkhuizen, L.

1998-01-01

A total of 182 Lactobacillus strains were screened for production of extracellular polysaccharides (EPS) by a new method: growth in liquid media with high sugar concentrations. Sixty EPS-positive strains were identified; 17 strains produced more than 100 mg/l soluble EPS. Sucrose was an excellent

K$^{-}$ over K$^{+}$ multiplicity ratio for kaons produced in DIS with a large fraction of the virtual-photon energy

CERN Document Server

Akhunzyanov, R.; The COMPASS collaboration; Alexeev, G.D.; Amoroso, A.; Andrieux, V.; Anfimov, N.V.; Anosov, V.; Antoshkin, A.; Augsten, K.; Augustyniak, W.; Austregesilo, A.; Azevedo, C.D.R.; Badełek, B.; Balestra, F.; Ball, M.; Barth, J.; Beck, R.; Bedfer, Y.; Bernhard, J.; Bicker, K.; Bielert, E.R.; Birsa, R.; Bodlak, M.; Bordalo, P.; Bradamante, F.; Bressan, A.; Büchele, M.; Burtsev, V.E.; Capozza, L.; Chang, W.-C.; Chatterjee, C.; Chiosso, M.; Chumakov, A.G.; Chung, S.-U.; Cicuttin, A.; Crespo, M.L.; Curiel, Q.; Dalla Torre, S.; Dasgupta, S.S.; Dasgupta, S.; Denisov, O.Yu.; Dhara, L.; Donskov, S.V.; Doshita, N.; Dreisbach, Ch.; Dünnweber, W.; Dusaev, R.R.; Dziewiecki, M.; Efremov, A.; Eversheim, P.D.; Faessler, M.; Ferrero, A.; Finger, M.; jr., M.Finger; Fischer, H.; Franco, C.; du Fresne von Hohenesche, N.; Friedrich, J.M.; Frolov, V.; Gautheron, F.; Gavrichtchouk, O.P.; Gerassimov, S.; Giarra, J.; Gnesi, I.; Gorzellik, M.; Grasso, A.; Gridin, A.; Grosse Perdekamp, M.; Grube, B.; Guskov, A.; Hahne, D.; Hamar, G.; von Harrach, D.; Heitz, R.; Herrmann, F.; Horikawa, N.; d'Hose, N.; Hsieh, C.-Y.; Huber, S.; Ishimoto, S.; Ivanov, A.; Ivanshin, Yu.; Iwata, T.; Jary, V.; Joosten, R.; Jörg, P.; Kabuß, E.; Kerbizi, A.; Ketzer, B.; Khaustov, G.V.; Khokhlov, Yu.A.; Kisselev, Yu.; Klein, F.; Koivuniemi, J.H.; Kolosov, V.N.; Kondo, K.; Konorov, I.; Konstantinov, V.F.; Kotzinian, A.M.; Kouznetsov, O.M.; Kral, Z.; Krämer, M.; Krinner, F.; Kroumchtein, Z.V.; Kulinich, Y.; Kunne, F.; Kurek, K.; Kurjata, R.P.; Kuznetsov, I.I.; Kveton, A.; Lednev, A.A.; Levchenko, E.A.; Levorato, S.; Lian, Y.-S.; Lichtenstadt, J.; Longo, R.; Lyubovitskij, V.E.; Maggiora, A.; Magnon, A.; Makins, N.; Makke, N.; Mallot, G.K.; Mamon, S.A.; Marchand, C.; Marianski, B.; Martin, A.; Marzec, J.; Matoušek, J.; Matsuda, H.; Matsuda, T.; Meshcheryakov, G.V.; Meyer, M.; Meyer, W.; Mikhailov, Yu.V.; Mikhasenko, M.; Mitrofanov, E.; Mitrofanov, N.; Miyachi, Y.; Moretti, A.; Nagaytsev, A.; Nerling, F.; Neyret, D.; Nový, J.; Nowak, W.-D.; Nukazuka, G.; Nunes, A.S.; Olshevsky, A.G.; Orlov, I.; Ostrick, M.; Panzieri, D.; Parsamyan, B.; Paul, S.; Peng, J.-C.; Pereira, F.; Pesaro, G.; Pešek, M.; Pešková, M.; Peshekhonov, D.V.; Pierre, N.; Platchkov, S.; Pochodzalla, J.; Polyakov, V.A.; Pretz, J.; Quaresma, M.; Quintans, C.; Ramos, S.; Regali, C.; Reicherz, G.; Riedl, C.; Ryabchikov, D.I.; Rybnikov, A.; Rychter, A.; Salac, R.; Samoylenko, V.D.; Sandacz, A.; Sarkar, S.; Savin, I.A.; Sawada, T.; Sbrizzai, G.; Schiavon, P.; Schmieden, H.; Seder, E.; Selyunin, A.; Silva, L.; Sinha, L.; Sirtl, S.; Slunecka, M.; Sozzi, F.; Smolik, J.; Srnka, A.; Steffen, D.; Stolarski, M.; Subrt, O.; Sulc, M.; Suzuki, H.; Szabelski, A.; Szameitat, T.; Sznajder, P.; Tasevsky, M.; Tessaro, S.; Tessarotto, F.; Thiel, A.; Tomsa, J.; Tosello, F.; Tskhay, V.; Uhl, S.; Vasilishin, B.I.; Vauth, A.; Veit, B.M.; Veloso, J.; Vidon, A.; Virius, M.; Wallner, S.; Wilfert, M.; Windmolders, R.; Zaremba, K.; Zavada, P.; Zavertyaev, M.; Zemlyanichkina, E.; Zhuravlev, N.; Ziembicki, M.

2018-01-01

The K$^{-}$ over K$^{+}$ multiplicity ratio is measured in deep-inelastic scattering, for the first time for kaons carrying a large fraction $z$ of the virtual-photon energy. The data were obtained by the COMPASS collaboration using a 160 GeV muon beam and an isoscalar $^6$LiD target. The regime of deep-inelastic scattering is ensured by requiring $Q^2>1$ (GeV/$c)^2$ for the photon virtuality and $W>5$ GeV/$c^2$ for the invariant mass of the produced hadronic system. Kaons are identified in the momentum range from 12 GeV/$c$ to 40 GeV/$c$, thereby restricting the range in Bjorken-$x$ to $0.010.75$. For very large values of $z$, $i.e.$ $z>0.8$, the results contradict expectations obtained using the formalism of (next-to-)leading order perturbative quantum chromodynamics. This may imply that cross-section factorisation or/and universality of (kaon) fragmentation functions do not hold. Our studies suggest that within this formalism an additional correction may be required, which takes into account th...

Cellulase producing microorganism ATCC 55702

Science.gov (United States)

Dees, H. Craig

1997-01-01

Bacteria which produce large amounts of cellulase--containing cell-free fermentate have been identified. The original bacterium (ATCC 55703) was genetically altered using nitrosoguanidine (MNNG) treatment to produce the enhanced cellulase producing bacterium (ATCC 55702), which was identified through replicate plating. ATCC 55702 has improved characteristics and qualifies for the degradation of cellulosic waste materials for fuel production, food processing, textile processing, and other industrial applications. ATCC 55702 is an improved bacterial host for genetic manipulations using recombinant DNA techniques, and is less likely to destroy genetic manipulations using standard mutagenesis techniques.

New ochratoxin A or sclerotium producing species in Aspergillus section Nigri

DEFF Research Database (Denmark)

Samson, R.A.; Frisvad, Jens Christian

2004-01-01

in Costa Rica and produces large pink to greyish brown sclerotia. Aspergillus lacticoffeatus was found on coffee beans in Venezuela and Indonesia, and is an effective producer of ochratoxin A. Aspergillus piperis was isolated from black ground pepper and produces large yellow to pink brown sclerotia...

A method for producing uniform dose distributions in the junction regions of large hinge angle electrol fields

International Nuclear Information System (INIS)

Zavgorodni, S.F.; Beckham, W.A.; Roos, D.E.

1996-01-01

The planning problems presented by abutting electron fields are well recognised. Junctioning electron fields with large hinge angle compounds the problems because of the creation of closely situated 'hot' and 'cold' spots. The technique involving a compensated superficial x-ray (SXR) field to treat the junction region between electron fields was developed and used in a particular clinical case (treatment of a squamous cell carcinoma of the forehead/scalp). The SXR beam parameters were chosen and the compensator was designed to make the SXR field complementary to the electron fields. Application of a compensated SXR field eliminated 'cold' spots in the junction region and minimised 'hot' spots to (110%). In the clinical case discusses the 'hot' spots due to the SXR field would not appear because of increased attenuation of the soft x-rays in bone. The technique proposed produces uniform dose distribution up to 3 cm deep and can be considered as an additional tool for dealing with electron fields junctioning problems. (author)

Hyper-saline produced water treatment for beneficial use

NARCIS (Netherlands)

Al-Furaiji, Mustafa

2016-01-01

Producing oil and gas is always accompanied with large amounts of effluent water, called “produced water” (PW). These huge quantities of water can be used (if treated efficiently and economically) for many useful purposes like industrial applications, irrigation, cattle and animal consumption, and

Determinants of Buying Behavior of Grain Producers: A Multiple Case Study with Mid and Large Size Producers in the State of Mato Grosso

Directory of Open Access Journals (Sweden)

Roberto Fava Scare

2013-12-01

Full Text Available In recent years, Brazilian agribusiness has demanded for inputs, capital goods, financial services and technology. In addition, there have been changes in the size of the properties, as well as in risk management and commercialization practices, and level of education and posture of those responsible for the decision making of agricultural enterprises. It is fundamental for companies that supply inputs and services to farmers to understand some variables in such changing environment, considering that they influence the business model and the buying behavior of rural producers. The purpose of this study is to develop knowledge and familiarity with the buying behavior of grain farmers in the State of Mato Grosso, with the intent of understanding how this behavior can be influenced by theproducer's profile and the farm features, as well as the risk and business management practices, the decision making, the sources of information, and the products and suppliers. In order to achieve such a goal,a multiple case study was developed by interviewing, face to face, three grain producers, from the State of Mato Grosso. The results demonstrate that the most influential determinants on the buying behavior of the interviewed producers were their level of involvement in the decision making process, the benefit they expect from each type of product, the size of their farming operation, the kind of yield production, and the crop rotation and its relation to productivity. Additionally, the ownership or not of the land, the business profitability, credit restrictions and risk management, they all influence the level of the producer's capitalization and consequently his choices of channels for acquiring inputs and capital goods. Last, though not less important, the sources of information and their reliability have an impact on the producer's loyalty to a brand, or to a local distributor or to a salesperson.

Large scale electrolysers

International Nuclear Information System (INIS)

B Bello; M Junker

2006-01-01

Hydrogen production by water electrolysis represents nearly 4 % of the world hydrogen production. Future development of hydrogen vehicles will require large quantities of hydrogen. Installation of large scale hydrogen production plants will be needed. In this context, development of low cost large scale electrolysers that could use 'clean power' seems necessary. ALPHEA HYDROGEN, an European network and center of expertise on hydrogen and fuel cells, has performed for its members a study in 2005 to evaluate the potential of large scale electrolysers to produce hydrogen in the future. The different electrolysis technologies were compared. Then, a state of art of the electrolysis modules currently available was made. A review of the large scale electrolysis plants that have been installed in the world was also realized. The main projects related to large scale electrolysis were also listed. Economy of large scale electrolysers has been discussed. The influence of energy prices on the hydrogen production cost by large scale electrolysis was evaluated. (authors)

Large Rotor Test Apparatus

Data.gov (United States)

Federal Laboratory Consortium — This test apparatus, when combined with the National Full-Scale Aerodynamics Complex, produces a thorough, full-scale test capability. The Large Rotor Test Apparatus...

Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine.

Science.gov (United States)

Louis, Petra; Flint, Harry J

2009-05-01

Butyrate-producing bacteria play a key role in colonic health in humans. This review provides an overview of the current knowledge of the diversity, metabolism and microbial ecology of this functionally important group of bacteria. Human colonic butyrate producers are Gram-positive firmicutes, but are phylogenetically diverse, with the two most abundant groups related to Eubacterium rectale/Roseburia spp. and to Faecalibacterium prausnitzii. Five different arrangements have been identified for the genes of the central pathway involved in butyrate synthesis, while in most cases butyryl-CoA : acetate CoA-transferase, rather than butyrate kinase, appears to perform the final step in butyrate synthesis. Mechanisms have been proposed recently in non-gut Clostridium spp. whereby butyrate synthesis can result in energy generation via both substrate-level phosphorylation and proton gradients. Here we suggest that these mechanisms also apply to the majority of butyrate producers from the human colon. The roles of these bacteria in the gut community and their influence on health are now being uncovered, taking advantage of the availability of cultured isolates and molecular methodologies. Populations of F. prausnitzii are reported to be decreased in Crohn's disease, for example, while populations of Roseburia relatives appear to be particularly sensitive to the diet composition in human volunteer studies.

IL-9-Producing Mast Cell Precursors and Food Allergy

Science.gov (United States)

2017-10-01

AWARD NUMBER: W81XWH-15-1-0517 TITLE: IL-9-Producing Mast Cell Precursors and Food Allergy PRINCIPAL INVESTIGATOR: Dr. Simon P. Hogan PhD...IL-9-Producing Mast Cell Precursors and Food Allergy 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Yui Hsi Wang, Sunil...threatening anaphylaxis. We have identified a novel multi-functional IL-9-producing mucosal mast cells (MMC9s) that produce large amounts of IL-9, IL

Large transverse momentum hadronic processes

International Nuclear Information System (INIS)

Darriulat, P.

1977-01-01

The possible relations between deep inelastic leptoproduction and large transverse momentum (psub(t)) processes in hadronic collisions are usually considered in the framework of the quark-parton picture. Experiments observing the structure of the final state in proton-proton collisions producing at least one large transverse momentum particle have led to the following conclusions: a large fraction of produced particles are uneffected by the large psub(t) process. The other products are correlated to the large psub(t) particle. Depending upon the sign of scalar product they can be separated into two groups of ''towards-movers'' and ''away-movers''. The experimental evidence are reviewed favouring such a picture and the properties are discussed of each of three groups (underlying normal event, towards-movers and away-movers). Some phenomenological interpretations are presented. The exact nature of away- and towards-movers must be further investigated. Their apparent jet structure has to be confirmed. Angular correlations between leading away and towards movers are very informative. Quantum number flow, both within the set of away and towards-movers, and between it and the underlying normal event, are predicted to behave very differently in different models

Developments in commercially produced microbials at Biochem Products

Science.gov (United States)

John Lublinkhof; Douglas H. Ross

1985-01-01

Biochem Products is part of a large industrial and scientific family - the Solvay Group. Solvay, headquartered in Brussels, Belgium is a multinational company with 46,000 employees worldwide. In the U.S., our working partners include a large polymer manufacturer, a peroxygen producer and a leading poultry and animal health products company. Biochem Products is a...

Large-volume excitation of air, argon, nitrogen and combustible mixtures by thermal jets produced by nanosecond spark discharges

Science.gov (United States)

Stepanyan, Sergey; Hayashi, Jun; Salmon, Arthur; Stancu, Gabi D.; Laux, Christophe O.

2017-04-01

This work presents experimental observations of strong expanding thermal jets following the application of nanosecond spark discharges. These jets propagate in a toroidal shape perpendicular to the interelectrode axis, with high velocities of up to 30 m s-1 and over distances of the order of a cm. Their propagation length is much larger than the thermal expansion region produced by the conventional millisecond sparks used in car engine ignition, thus greatly improving the volumetric excitation of gas mixtures. The shape and velocity of the jets is found to be fairly insensitive to the shape of the electrodes. In addition, their spatial extent is found to increase with the number of nanosecond sparks and with the discharge voltage, and to decrease slightly with the pressure between 1 and 7 atm at constant applied voltage. Finally, this thermal jet phenomenon is observed in experiments conducted with many types of gas mixtures, including air, nitrogen, argon, and combustible CH4/air mixtures. This makes nanosecond repetitively pulsed discharges particularly attractive for aerodynamic flow control or plasma-assisted combustion because of their ability to excite large volumes of gas, typically about 100 times the volume of the discharge.

Natural gas supply - a producer's perspective

International Nuclear Information System (INIS)

Papa, M.G.

1994-01-01

The supply of natural gas from the producers standpoint is discussed. The following factors in the marketing demand for natural gas are considered to be important: gas demand is growing, U.S. gas resource base is large, chronic gas bubble has shrunk, and North American supply is more resilient than expected

ANAEROBIC BIOLOGICAL TREATMENT OF PRODUCED WATER

Energy Technology Data Exchange (ETDEWEB)

John R. Gallagher

2001-07-31

During the production of oil and gas, large amounts of water are brought to the surface and must be disposed of in an environmentally sensitive manner. This is an especially difficult problem in offshore production facilities where space is a major constraint. The chief regulatory criterion for produced water is oil and grease. Most facilities have little trouble meeting this criterion using conventional oil-water separation technologies. However, some operations have significant amounts of naphthenic acids in the water that behave as oil and grease but are not well removed by conventional technologies. Aerobic biological treatment of naphthenic acids in simulated-produced water has been demonstrated by others; however, the system was easily overloaded by the large amounts of low-molecular-weight organic acids often found in produced waters. The objective of this research was to determine the ability of an anaerobic biological system to treat these organic acids in a simulated produced water and to examine the potential for biodegradation of the naphthenic acids in the anaerobic environment. A small fixed-film anaerobic biological reactor was constructed and adapted to treat a simulated produced water. The bioreactor was tubular, with a low-density porous glass packing material. The inocula to the reactor was sediment from a produced-water holding pond from a municipal anaerobic digester and two salt-loving methanogenic bacteria. During start-up, the feed to the reactor contained glucose as well as typical produced-water components. When glucose was used, rapid gas production was observed. However, when glucose was eliminated and the major organic component was acetate, little gas was generated. Methane production from acetate may have been inhibited by the high salt concentrations, by sulfide, or because of the lack, despite seeding, of microbes capable of converting acetate to methane. Toluene, a minor component of the produced water (0.1 g/L) was removed in the

Impact of heuristics in clustering large biological networks.

Science.gov (United States)

Shafin, Md Kishwar; Kabir, Kazi Lutful; Ridwan, Iffatur; Anannya, Tasmiah Tamzid; Karim, Rashid Saadman; Hoque, Mohammad Mozammel; Rahman, M Sohel

2015-12-01

Traditional clustering algorithms often exhibit poor performance for large networks. On the contrary, greedy algorithms are found to be relatively efficient while uncovering functional modules from large biological networks. The quality of the clusters produced by these greedy techniques largely depends on the underlying heuristics employed. Different heuristics based on different attributes and properties perform differently in terms of the quality of the clusters produced. This motivates us to design new heuristics for clustering large networks. In this paper, we have proposed two new heuristics and analyzed the performance thereof after incorporating those with three different combinations in a recently celebrated greedy clustering algorithm named SPICi. We have extensively analyzed the effectiveness of these new variants. The results are found to be promising. Copyright © 2015 Elsevier Ltd. All rights reserved.

Producing superhydrophobic roof tiles

International Nuclear Information System (INIS)

Carrascosa, Luis A M; Facio, Dario S; Mosquera, Maria J

2016-01-01

Superhydrophobic materials can find promising applications in the field of building. However, their application has been very limited because the synthesis routes involve tedious processes, preventing large-scale application. A second drawback is related to their short-term life under outdoor conditions. A simple and low-cost synthesis route for producing superhydrophobic surfaces on building materials is developed and their effectiveness and their durability on clay roof tiles are evaluated. Specifically, an organic–inorganic hybrid gel containing silica nanoparticles is produced. The nanoparticles create a densely packed coating on the roof tile surface in which air is trapped. This roughness produces a Cassie–Baxter regime, promoting superhydrophobicity. A surfactant, n-octylamine, was also added to the starting sol to catalyze the sol–gel process and to coarsen the pore structure of the gel network, preventing cracking. The application of ultrasound obviates the need to use volatile organic compounds in the synthesis, thereby making a ‘green’ product. It was also demonstrated that a co-condensation process effective between the organic and inorganic species is crucial to obtain durable and effective coatings. After an aging test, high hydrophobicity was maintained and water absorption was completely prevented for the roof tile samples under study. However, a transition from a Cassie–Baxter to a Wenzel state regime was observed as a consequence of the increase in the distance between the roughness pitches produced by the aging of the coating. (paper)

Monetary Shocks in Models with Inattentive Producers.

Science.gov (United States)

Alvarez, Fernando E; Lippi, Francesco; Paciello, Luigi

2016-04-01

We study models where prices respond slowly to shocks because firms are rationally inattentive. Producers must pay a cost to observe the determinants of the current profit maximizing price, and hence observe them infrequently. To generate large real effects of monetary shocks in such a model the time between observations must be long and/or highly volatile. Previous work on rational inattentiveness has allowed for observation intervals that are either constant-but-long ( e.g . Caballero, 1989 or Reis, 2006) or volatile-but-short ( e.g . Reis's, 2006 example where observation costs are negligible), but not both. In these models, the real effects of monetary policy are small for realistic values of the duration between observations. We show that non-negligible observation costs produce both of these effects: intervals between observations are infrequent and volatile. This generates large real effects of monetary policy for realistic values of the average time between observations.

Large-Scale Purification of r28M: A Bispecific scFv Antibody Targeting Human Melanoma Produced in Transgenic Cattle.

Directory of Open Access Journals (Sweden)

Katrin Spiesberger

Full Text Available 30 years ago, the potential of bispecific antibodies to engage cytotoxic T cells for the lysis of cancer cells was discovered. Today a variety of bispecific antibodies against diverse cell surface structures have been developed, the majority of them produced in mammalian cell culture systems. Beside the r28M, described here, no such bispecific antibody is known to be expressed by transgenic livestock, although various biologicals for medical needs are already harvested-mostly from the milk-of these transgenics. In this study we investigated the large-scale purification and biological activity of the bispecific antibody r28M, expressed in the blood of transgenic cattle. This tandem single-chain variable fragment antibody is designed to target human CD28 and the melanoma/glioblastoma-associated cell surface chondroitin sulfate proteoglycan 4 (CSPG4.With the described optimized purification protocol an average yield of 30 mg enriched r28M fraction out of 2 liters bovine plasma could be obtained. Separation of this enriched fraction by size exclusion chromatography into monomers, dimers and aggregates and further testing regarding the biological activity revealed the monomer fraction as being the most appropriate one to continue working with. The detailed characterization of the antibody's activity confirmed its high specificity to induce the killing of CSPG4 positive cells. In addition, first insights into tumor cell death pathways mediated by r28M-activated peripheral blood mononuclear cells were gained. In consideration of possible applications in vivo we also tested the effect of the addition of different excipients to r28M.Summing up, we managed to purify monomeric r28M from bovine plasma in a large-scale preparation and could prove that its biological activity is unaffected and still highly specific and thus, might be applicable for the treatment of melanoma.

Produce Your Own: A Community Gardening Program

Science.gov (United States)

Miller, JoLynn; Arnold, Shannon

2012-01-01

Many County Extension offices offer an adult Master Gardener Program, which includes advanced gardening training, short courses, newsletters, and conferences. However, with the comprehensive training provided comes a large time commitment. The Produce Your Own program was created to introduce adults to gardening in a similar manner, but with…

Produced Water Management and Beneficial Use

International Nuclear Information System (INIS)

Brown, Terry; Frost, Carol; Hayes, Thomas; Heath, Leo; Johnson, Drew; Lopez, David; Saffer, Demian; Urynowicz, Michael; Wheaton, John; Zoback, Mark

2007-01-01

Large quantities of water are associated with the production of coalbed methane (CBM) in the Powder River Basin (PRB) of Wyoming. The chemistry of co-produced water often makes it unsuitable for subsequent uses such as irrigated agriculture. However, co-produced waters have substantial potential for a variety of beneficial uses. Achieving this potential requires the development of appropriate water management strategies. There are several unique characteristics of co-produced water that make development of such management strategies a challenge. The production of CBM water follows an inverse pattern compared to traditional wells. CBM wells need to maintain low reservoir pressures to promote gas production. This need renders the reinjection of co-produced waters counterproductive. The unique water chemistry of co-produced water can reduce soil permeability, making surface disposal difficult. Unlike traditional petroleum operations where co-produced water is an undesirable by-product, co-produced water in the PRB often is potable, making it a highly valued resource in arid western states. This research project developed and evaluated a number of water management options potentially available to CBM operators. These options, which focus on cost-effective and environmentally-sound practices, fall into five topic areas: Minimization of Produced Water, Surface Disposal, Beneficial Use, Disposal by Injection and Water Treatment. The research project was managed by the Colorado Energy Research Institute (CERI) at the Colorado School of Mines (CSM) and involved personnel located at CERI, CSM, Stanford University, Pennsylvania State University, the University of Wyoming, the Argonne National Laboratory, the Gas Technology Institute, the Montana Bureau of Mining and Geology and PVES Inc., a private firm

Produced Water Management and Beneficial Use

Energy Technology Data Exchange (ETDEWEB)

Terry Brown; Carol Frost; Thomas Hayes; Leo Heath; Drew Johnson; David Lopez; Demian Saffer; Michael Urynowicz; John Wheaton; Mark Zoback

2007-10-31

Large quantities of water are associated with the production of coalbed methane (CBM) in the Powder River Basin (PRB) of Wyoming. The chemistry of co-produced water often makes it unsuitable for subsequent uses such as irrigated agriculture. However, co-produced waters have substantial potential for a variety of beneficial uses. Achieving this potential requires the development of appropriate water management strategies. There are several unique characteristics of co-produced water that make development of such management strategies a challenge. The production of CBM water follows an inverse pattern compared to traditional wells. CBM wells need to maintain low reservoir pressures to promote gas production. This need renders the reinjection of co-produced waters counterproductive. The unique water chemistry of co-produced water can reduce soil permeability, making surface disposal difficult. Unlike traditional petroleum operations where co-produced water is an undesirable by-product, co-produced water in the PRB often is potable, making it a highly valued resource in arid western states. This research project developed and evaluated a number of water management options potentially available to CBM operators. These options, which focus on cost-effective and environmentally-sound practices, fall into five topic areas: Minimization of Produced Water, Surface Disposal, Beneficial Use, Disposal by Injection and Water Treatment. The research project was managed by the Colorado Energy Research Institute (CERI) at the Colorado School of Mines (CSM) and involved personnel located at CERI, CSM, Stanford University, Pennsylvania State University, the University of Wyoming, the Argonne National Laboratory, the Gas Technology Institute, the Montana Bureau of Mining and Geology and PVES Inc., a private firm.

Ion-Ion Plasmas Produced by Electron Beams

Science.gov (United States)

Fernsler, R. F.; Leonhardt, D.; Walton, S. G.; Meger, R. A.

2001-10-01

The ability of plasmas to etch deep, small-scale features in materials is limited by localized charging of the features. The features charge because of the difference in electron and ion anisotropy, and thus one solution now being explored is to use ion-ion plasmas in place of electron-ion plasmas. Ion-ion plasmas are effectively electron-free and consist mainly of positive and negative ions. Since the two ion species behave similarly, localized charging is largely eliminated. However, the only way to produce ion-ion plasmas at low gas pressure is to convert electrons into negative ions through two-body attachment to neutrals. While the electron attachment rate is large at low electron temperatures (Te < 1 eV) in many of the halogen gases used for processing, these temperatures occur in most reactors only during the afterglow when the heating fields are turned off and the plasma is decaying. By contrast, Te is low nearly all the time in plasmas produced by electron beams, and therefore electron beams can potentially produce ion-ion plasmas continuously. The theory of ion-ion plasmas formed by pulsed electron beams is examined in this talk and compared with experimental results presented elsewhere [1]. Some general limitations of ion-ion plasmas, including relatively low flux levels, are discussed as well. [1] See the presentation by D. Leonhardt et al. at this conference.

Choice of large projects

Energy Technology Data Exchange (ETDEWEB)

Harris, R

1978-08-01

Conventional cost/benefit or project analysis has generally not taken into account circumstances in which the project under consideration is large enough that its introduction to the economy would have significant general equilibrium effects. In this paper, rules are examined that would indicate whether such large projects should be accepted or rejected. The rules utilize information yielded by before-project and after-project equilibrium prices and production data. Rules are developed for the undistorted ''first-best'' case, the case in which the fixed costs of the project are covered by distortionary taxation, and for the case of projects producing public goods. 34 references.

ANAEROBIC BIOLOGICAL TREATMENT OF PRODUCED WATER; TOPICAL

International Nuclear Information System (INIS)

John R. Gallagher

2001-01-01

During the production of oil and gas, large amounts of water are brought to the surface and must be disposed of in an environmentally sensitive manner. This is an especially difficult problem in offshore production facilities where space is a major constraint. The chief regulatory criterion for produced water is oil and grease. Most facilities have little trouble meeting this criterion using conventional oil-water separation technologies. However, some operations have significant amounts of naphthenic acids in the water that behave as oil and grease but are not well removed by conventional technologies. Aerobic biological treatment of naphthenic acids in simulated-produced water has been demonstrated by others; however, the system was easily overloaded by the large amounts of low-molecular-weight organic acids often found in produced waters. The objective of this research was to determine the ability of an anaerobic biological system to treat these organic acids in a simulated produced water and to examine the potential for biodegradation of the naphthenic acids in the anaerobic environment. A small fixed-film anaerobic biological reactor was constructed and adapted to treat a simulated produced water. The bioreactor was tubular, with a low-density porous glass packing material. The inocula to the reactor was sediment from a produced-water holding pond from a municipal anaerobic digester and two salt-loving methanogenic bacteria. During start-up, the feed to the reactor contained glucose as well as typical produced-water components. When glucose was used, rapid gas production was observed. However, when glucose was eliminated and the major organic component was acetate, little gas was generated. Methane production from acetate may have been inhibited by the high salt concentrations, by sulfide, or because of the lack, despite seeding, of microbes capable of converting acetate to methane. Toluene, a minor component of the produced water (0.1 g/L) was removed in the

A critical review of producers of small lactone mycotoxins: patulin, penicillic acid and moniliformin

DEFF Research Database (Denmark)

Frisvad, J.C.

2018-01-01

A very large number of filamentous fungi has been reported to produce the small lactone mycotoxins patulin, penicillic acid and moniliformin. Among the 167 reported fungal producers of patulin, only production by 29 species could be confirmed. Patulin is produced by 3 Aspergillus species, 3...

The large-s field-reversed configuration experiment

International Nuclear Information System (INIS)

Hoffman, A.L.; Carey, L.N.; Crawford, E.A.; Harding, D.G.; DeHart, T.E.; McDonald, K.F.; McNeil, J.L.; Milroy, R.D.; Slough, J.T.; Maqueda, R.; Wurden, G.A.

1993-01-01

The Large-s Experiment (LSX) was built to study the formation and equilibrium properties of field-reversed configurations (FRCs) as the scale size increases. The dynamic, field-reversed theta-pinch method of FRC creation produces axial and azimuthal deformations and makes formation difficult, especially in large devices with large s (number of internal gyroradii) where it is difficult to achieve initial plasma uniformity. However, with the proper technique, these formation distortions can be minimized and are then observed to decay with time. This suggests that the basic stability and robustness of FRCs formed, and in some cases translated, in smaller devices may also characterize larger FRCs. Elaborate formation controls were included on LSX to provide the initial uniformity and symmetry necessary to minimize formation disturbances, and stable FRCs could be formed up to the design goal of s = 8. For x ≤ 4, the formation distortions decayed away completely, resulting in symmetric equilibrium FRCs with record confinement times up to 0.5 ms, agreeing with previous empirical scaling laws (τ∝sR). Above s = 4, reasonably long-lived (up to 0.3 ms) configurations could still be formed, but the initial formation distortions were so large that they never completely decayed away, and the equilibrium confinement was degraded from the empirical expectations. The LSX was only operational for 1 yr, and it is not known whether s = 4 represents a fundamental limit for good confinement in simple (no ion beam stabilization) FRCs or whether it simply reflects a limit of present formation technology. Ideally, s could be increased through flux buildup from neutral beams. Since the addition of kinetic or beam ions will probably be desirable for heating, sustainment, and further stabilization of magnetohydrodynamic modes at reactor-level s values, neutral beam injection is the next logical step in FRC development. 24 refs., 21 figs., 2 tabs

Electromagnetic surface waves for large-area RF plasma productions between large-area planar electrodes

International Nuclear Information System (INIS)

Nonaka, S.

1992-01-01

Recently, large-area plasma production has been tested by means of a 13.56 MHz radio-frequency (RF) discharge between a pair of large-area planar electrodes, approximately 0.5 m x 1.4 m, as one of the semiconductor technologies for fabrication of large-area amorphous silicon solar cells in the ''Sunshine Project'' of the Agency of Industrial Science and Technology in Japan. We also confirmed long plasma production between a pair of long electrodes. In this paper, normal electromagnetic (EM) waves propagating in a region between a planar waveguide with one plasma and two dielectric layers are analyzed in order to study the feasibility of large-area plasma productions by EM wave-discharges between a pair of large-area RF electrodes larger than the half-wavelength of RF wave. In conclusion, plasmas higher than an electron plasma frequency will be produced by an odd TMoo surface mode. (author) 4 refs., 3 figs

Use of Aerial high resolution visible imagery to produce large river bathymetry: a multi temporal and spatial study over the by-passed Upper Rhine

Science.gov (United States)

Béal, D.; Piégay, H.; Arnaud, F.; Rollet, A.; Schmitt, L.

2011-12-01

Aerial high resolution visible imagery allows producing large river bathymetry assuming that water depth is related to water colour (Beer-Bouguer-Lambert law). In this paper we aim at monitoring Rhine River geometry changes for a diachronic study as well as sediment transport after an artificial injection (25.000 m3 restoration operation). For that a consequent data base of ground measurements of river depth is used, built on 3 different sources: (i) differential GPS acquisitions, (ii) sounder data and (iii) lateral profiles realized by experts. Water depth is estimated using a multi linear regression over neo channels built on a principal component analysis over red, green and blue bands and previously cited depth data. The study site is a 12 km long reach of the by-passed section of the Rhine River that draws French and German border. This section has been heavily impacted by engineering works during the last two centuries: channelization since 1842 for navigation purposes and the construction of a 45 km long lateral canal and 4 consecutive hydroelectric power plants of since 1932. Several bathymetric models are produced based on 3 different spatial resolutions (6, 13 and 20 cm) and 5 acquisitions (January, March, April, August and October) since 2008. Objectives are to find the optimal spatial resolution and to characterize seasonal effects. Best performances according to the 13 cm resolution show a 18 cm accuracy when suspended matters impacted less water transparency. Discussions are oriented to the monitoring of the artificial reload after 2 flood events during winter 2010-2011. Bathymetric models produced are also useful to build 2D hydraulic model's mesh.

Evaluation of Volatile Organic Compounds and Carbonyl Compounds Present in the Cabins of Newly Produced, Medium- and Large-Size Coaches in China

Directory of Open Access Journals (Sweden)

Yan-Yang Lu

2016-06-01

Full Text Available An air-conditioned coach is an important form of transportation in modern motorized society; as a result, there is an increasing concern of in-vehicle air pollution. In this study, we aimed to identify and quantify the levels of volatile organic compounds (VOCs and carbonyl compounds (CCs in air samples collected from the cabins of newly produced, medium- and large-size coaches. Among the identified VOCs and CCs, toluene, ethylbenzene, xylene, formaldehyde, acetaldehyde, acrolein/acetone, and isovaleraldehyde were relatively abundant in the cabins. Time was found to affect the emissions of the contaminants in the coaches. Except for benzaldehyde, valeraldehyde and benzene, the highest in-vehicle concentrations of VOCs and CCs were observed on the 15th day after coming off the assembly line, and the concentrations exhibited an approximately inverted U-shaped pattern as a function of time. Interestingly, this study also showed that the interior temperature of the coaches significantly affected the VOCs emissions from the interior materials, whereas the levels of CCs were mainly influenced by the relative humidity within the coaches. In China, guidelines and regulations for the in-vehicle air quality assessment of the coaches have not yet been issued. The results of this study provide further understanding of the in-vehicle air quality of air-conditioned coaches and can be used in the development of both specific and general rules regarding medium- and large-size coaches.

The economics of producing energy crops

International Nuclear Information System (INIS)

Shapouri, H.; Duffield, J.

1993-01-01

The US agricultural sector has an immense supply of natural resources which can be used to product energy. Production of energy from these resources could stimulate economic growth, improve environmental quality, and enhance energy security. However, producing feedstocks and converting biomass to energy require large amounts of capital, equipment, labor, and processing facilities. This paper looks at the costs and benefits of producing energy crops for fuel conversion. A review of studies and crop data show that the cost of growing and converting various feedstocks with current technology is greater than the cost of producing conventional fuels. Conventional motor fuels have a price advantage over biofuels, but market prices don't always reflect the cost of negative externalities imposed on society. Government decisions to invest in alternative energy sources should be based on research that includes the environmental costs and benefits of energy production. The future of biofuels will depend on the continuation of government research and incentive programs. As new technologies advance, the costs of processing energy crops and residues will fall, making biofuels more competitive in energy markets

The future of UK gas producers

International Nuclear Information System (INIS)

Hallas, P.A.

1991-01-01

Traditionally, an oil company wishing to develop UK gas reserves almost always faced a protracted gas sales negotiation with British Gas. British Gas then had an effective monopoly in the resale of that gas to final consumers. This traditional pattern is now in a process of fundamental change, as a result of recent UK gas market re-regulation and the emergence of a new large scale opportunity to sell gas for power generation. The impact of these changes is still not very well understood outside a relatively small group of gas specialists but is likely to be significant for British Gas, consumers and UK gas producers. This paper outlines the background to the recent changes, the possible future of UK gas marketing and the likely impact on gas producers in the North Sea

Construction of acetoin high-producing Bacillus subtilis strain

Directory of Open Access Journals (Sweden)

Yanjun Tian

2016-07-01

Full Text Available This paper describes the construction and selection of a high-producing mutant, Bacillus subtilis HB-32, with enhanced acetoin yield and productivity. The mutant was obtained by the protoplast fusion of a Bacillus subtilis mutant TH-49 (Val− producing acetoin and Bacillus licheniformis AD-30 producing α-acetolactate decarboxylase, with the fusogen polyethylene glycol and after the regeneration and selection, etc. of the fusant. The acetoin production reached 49.64 g/L, which is an increase of 61.8% compared to that of B. subtilis strain TH-49. Random amplified polymorphic DNA analysis was performed to determine the mutagenic and protoplast fusion effects and the genomic changes in the acetoin high-producing strain compared to the parent strains at the molecular level. The constructed strain was shown to be promising for large-scale acetoin production. Future studies should focus on the application of the mutant strain in practice.

Availability, quality and price of produce in low-income neighbourhood food stores in California raise equity issues.

Science.gov (United States)

Gosliner, Wendi; Brown, Daniel M; Sun, Betty C; Woodward-Lopez, Gail; Crawford, Patricia B

2018-06-01

To assess produce availability, quality and price in a large sample of food stores in low-income neighbourhoods in California. Cross-sectional statewide survey. Between 2011 and 2015, local health departments assessed store type, WIC (Supplemental Nutrition Program for Women, Infants, and Children)/SNAP (Supplemental Nutrition Assistance Program) participation, produce availability, quality and price of selected items in stores in low-income neighbourhoods. Secondary data provided reference chain supermarket produce prices matched by county and month. t Tests and ANOVA examined differences by store type; regression models examined factors associated with price. Large grocery stores (n 231), small markets (n 621) and convenience stores (n 622) in 225 neighbourhoods. Produce in most large groceries was rated high quality (97 % of fruits, 98 % of vegetables), but not in convenience stores (25 % fruits, 14 % vegetables). Small markets and convenience stores participating in WIC and/or SNAP had better produce availability, variety and quality than non-participating stores. Produce prices across store types were, on average, higher than reference prices from matched chain supermarkets (27 % higher in large groceries, 37 % higher in small markets, 102 % higher in convenience stores). Price was significantly inversely associated with produce variety, adjusting for quality, store type, and SNAP and WIC participation. The study finds that fresh produce is more expensive in low-income neighbourhoods and that convenience stores offer more expensive, poorer-quality produce than other stores. Variety is associated with price and most limited in convenience stores, suggesting more work is needed to determine how convenience stores can provide low-income consumers with access to affordable, high-quality produce. WIC and SNAP can contribute to the solution.

Health risk assessment for radium discharged in produced waters

International Nuclear Information System (INIS)

Hamilton, L.D.; Meinhold, A.F.; Nagy, J.

1991-01-01

Produced water generated during the production of oil and gas can contain enhanced levels of radium. This naturally occurring radioactive material (NORM) is discharged into freshwater streams, estuarine, coastal and outer continental shelf waters. Large volumes of produced waters are discharged to coastal waters along the Gulf Coast of Louisiana. The Gulf of Mexico is an important producer of fish and shellfish, and there is concern that radium discharged to coastal Louisiana could contaminate fish and shellfish used by people for food, and present a significant increase in cancer risk. This paper describes a screening-level assessment of the potential cancer risks posed by radium discharged to coastal Louisiana in oil-field produced waters. This screening analysis was performed to determine if a more comprehensive and realistic assessment is necessary, and because of the conservative assumptions embedded in the analysis overestimates the risk associated with the discharge of radium in produced waters. Two isotopes of radium (Ra-226 and Ra-228) are the radionuclides of most concern in produced water in terms of potential human health effects

Phenomenology of a pseudo-scalar inflaton: naturally large nongaussianity

International Nuclear Information System (INIS)

Barnaby, Neil; Namba, Ryo; Peloso, Marco

2011-01-01

Many controlled realizations of chaotic inflation employ pseudo-scalar axions. Pseudo-scalars φ are naturally coupled to gauge fields through cφF F-tilde . In the presence of this coupling, gauge field quanta are copiously produced by the rolling inflaton. The produced gauge quanta, in turn, source inflaton fluctuations via inverse decay. These new cosmological perturbations add incoherently with the ''vacuum'' perturbations, and are highly nongaussian. This provides a natural mechanism to generate large nongaussianity in single or multi field slow-roll inflation. The resulting phenomenological signatures are highly distinctive: large nongaussianity of (nearly) equilateral shape, in addition to detectably large values of both the scalar spectral tilt and tensor-to-scalar ratio (both being typical of large field inflation). The WMAP bound on nongaussianity implies that the coupling c of the pseudo-scalar inflaton to any gauge field must be smaller than about 10 2 M p −1

The spatial thickness distribution of metal films produced by large area pulsed laser deposition

DEFF Research Database (Denmark)

Pryds, Nini; Schou, Jørgen; Linderoth, Søren

2007-01-01

Thin films of metals have been deposited in the large-area Pulsed Laser Deposition (PLD) Facility at Riso National Laboratory. Thin films of Ag and Ni were deposited with laser pulses from an excimer laser at 248 nm with a rectangular beam spot at a fluence of 10 J/cm(2) on glass substrates of 127...

Large-amplitude traveling ionospheric distrubance produced by the May 18, 1980, explosion of Mount St. Helens

International Nuclear Information System (INIS)

Roberts, D.H.; Klobuchar, J.A.; Fougere, P.F.; Hendrickson, D.H.

1982-01-01

A remarkable long-lived, large-scale traveling ionospheric disturbance (TID), excited by the May 18, 1980, explosion of Mount St. Helens, has been detected in total electron content monitor data. Oscillatory perturbations in the electron column density of the ionosphere with amplitudes about 10% of the nominal daytime content were detected at three stations whose ionospheric penetration points lie between 1610 and 1890 km from Mount St. Helens. Smaller perturbations were detected at five of six additional stations between 3760 and 4950 km away. The period of the TID increased linearly with great-circle distance from Mount St. Helens, ranging from roughly-equal37 min at the nearest station to roughly-equal116 min at the most distant one. The TID persisted for at least four cycles at the three close stations and three cycles at the more distant stations and was qualitatively similar to TID's produced by the low-altitude thermonuclear detonations of the 1960's. The disturbance front of this TID accelerated from an average velocity of roughly-equal350 m/s between Mt. St. Helens and the close stations to an average velocity of roughly-equal550 m/s to the more distant ones.A model based on the free wave response of an isothermal atmosphere to a point disturbance provides a good fit to the data at the three closest stations, but no such model can account for all of the data. Modeling of the long-distance behavior of the Mount St. Helens TID in terms of upper-atmosphere guided gravity waves is complicated by the requirement of exciting them by a ground-level explosion. There was no evidence for a strong supersonic shock wave in the ionosphere. As a result, the Mount St. Helens disturbance may prove to be a cleaner test of detailed theories of the point excitation and propagation of gravity waves in a realistic atmosphere than were TID's excited by thermonuclear weapons

Learning from large scale neural simulations

DEFF Research Database (Denmark)

Serban, Maria

2017-01-01

Large-scale neural simulations have the marks of a distinct methodology which can be fruitfully deployed to advance scientific understanding of the human brain. Computer simulation studies can be used to produce surrogate observational data for better conceptual models and new how...

Large Scale Composite Manufacturing for Heavy Lift Launch Vehicles

Science.gov (United States)

Stavana, Jacob; Cohen, Leslie J.; Houseal, Keth; Pelham, Larry; Lort, Richard; Zimmerman, Thomas; Sutter, James; Western, Mike; Harper, Robert; Stuart, Michael

2012-01-01

Risk reduction for the large scale composite manufacturing is an important goal to produce light weight components for heavy lift launch vehicles. NASA and an industry team successfully employed a building block approach using low-cost Automated Tape Layup (ATL) of autoclave and Out-of-Autoclave (OoA) prepregs. Several large, curved sandwich panels were fabricated at HITCO Carbon Composites. The aluminum honeycomb core sandwich panels are segments of a 1/16th arc from a 10 meter cylindrical barrel. Lessons learned highlight the manufacturing challenges required to produce light weight composite structures such as fairings for heavy lift launch vehicles.

Characterization of anti-P monoclonal antibodies directed against the ribosomal protein-RNA complex antigen and produced using Murphy Roths large autoimmune-prone mice.

Science.gov (United States)

Sato, H; Onozuka, M; Hagiya, A; Hoshino, S; Narita, I; Uchiumi, T

2015-02-01

Autoantibodies, including anti-ribosomal P proteins (anti-P), are thought to be produced by an antigen-driven immune response in systemic lupus erythematosus (SLE). To test this hypothesis, we reconstituted the ribosomal antigenic complex in vitro using human P0, phosphorylated P1 and P2 and a 28S rRNA fragment covering the P0 binding site, and immunized Murphy Roths large (MRL)/lrp lupus mice with this complex without any added adjuvant to generate anti-P antibodies. Using hybridoma technology, we subsequently obtained 34 clones, each producing an anti-P monoclonal antibody (mAb) that recognized the conserved C-terminal tail sequence common to all three P proteins. We also obtained two P0-specific monoclonal antibodies, but no antibody specific to P1, P2 or rRNA fragment. Two types of mAbs were found among these anti-P antibodies: one type (e.g. 9D5) reacted more strongly with the phosphorylated P1 and P2 than that with their non-phosphorylated forms, whereas the other type (e.g. 4H11) reacted equally with both phosphorylated and non-phosphorylated forms of P1/P2. Both 9D5 and 4H11 inhibited the ribosome/eukaryotic elongation factor-2 (eEF-2)-coupled guanosine triphosphate (GTP)ase activity. However, preincubation with a synthetic peptide corresponding to the C-terminal sequence common to all three P proteins, but not the peptide that lacked the last three C-terminal amino acids, mostly prevented the mAb-induced inhibition of GTPase activity. Thus, at least two types of anti-P were produced preferentially following the immunization of MRL mice with the reconstituted antigenic complex. Presence of multiple copies of the C-termini, particularly that of the last three C-terminal amino acid residues, in the antigenic complex appears to contribute to the immunogenic stimulus. © 2014 British Society for Immunology.

Characterization of anti-P monoclonal antibodies directed against the ribosomal protein–RNA complex antigen and produced using Murphy Roths large autoimmune-prone mice

Science.gov (United States)

Sato, H; Onozuka, M; Hagiya, A; Hoshino, S; Narita, I; Uchiumi, T

2015-01-01

Autoantibodies, including anti-ribosomal P proteins (anti-P), are thought to be produced by an antigen-driven immune response in systemic lupus erythematosus (SLE). To test this hypothesis, we reconstituted the ribosomal antigenic complex in vitro using human P0, phosphorylated P1 and P2 and a 28S rRNA fragment covering the P0 binding site, and immunized Murphy Roths large (MRL)/lrp lupus mice with this complex without any added adjuvant to generate anti-P antibodies. Using hybridoma technology, we subsequently obtained 34 clones, each producing an anti-P monoclonal antibody (mAb) that recognized the conserved C-terminal tail sequence common to all three P proteins. We also obtained two P0-specific monoclonal antibodies, but no antibody specific to P1, P2 or rRNA fragment. Two types of mAbs were found among these anti-P antibodies: one type (e.g. 9D5) reacted more strongly with the phosphorylated P1 and P2 than that with their non-phosphorylated forms, whereas the other type (e.g. 4H11) reacted equally with both phosphorylated and non-phosphorylated forms of P1/P2. Both 9D5 and 4H11 inhibited the ribosome/eukaryotic elongation factor-2 (eEF-2)-coupled guanosine triphosphate (GTP)ase activity. However, preincubation with a synthetic peptide corresponding to the C-terminal sequence common to all three P proteins, but not the peptide that lacked the last three C-terminal amino acids, mostly prevented the mAb-induced inhibition of GTPase activity. Thus, at least two types of anti-P were produced preferentially following the immunization of MRL mice with the reconstituted antigenic complex. Presence of multiple copies of the C-termini, particularly that of the last three C-terminal amino acid residues, in the antigenic complex appears to contribute to the immunogenic stimulus. PMID:25255895

Relationships between food producers and retail chains: From a constructivist perspective

DEFF Research Database (Denmark)

Skytte, Hans

This paper presents preliminary results from a large project in which we developed a new way of looking at interaction and relationships between companies. Our main focus of interest in the project was the relationships between food producers and retail chains. The project investigated the cooper......This paper presents preliminary results from a large project in which we developed a new way of looking at interaction and relationships between companies. Our main focus of interest in the project was the relationships between food producers and retail chains. The project investigated...... the cooperation between Danish food producers and retail chains in four countries regarding trade in pork and pork-based products. The paradigmatic outset in the project was the constructivist paradigm. Based on theories on organisational identity, organisational image, organisational fields, plausibility......, product development, and construction of meaning and shared meaning, an analytical framework was developed. The theoretical framework subsequently - founded on a grounded theory approach - was used as the basis for the analysis. The paper concludes with a number of recommen¬dations for food producers...

Diseases in insects produced for food and feed

DEFF Research Database (Denmark)

Eilenberg, Jørgen; Vlak, J.M.; Nielsen-Leroux, C.

2015-01-01

Increased production of insects on a large scale for food and feed will likely lead to many novel challenges, including problems with diseases. We provide an overview of important groups of insect pathogens, which can cause disease in insects produced for food and feed. Main characteristics of each...... pathogen group (viruses, bacteria, fungi, protists and nematodes) are described and illustrated, with a selection of examples from the most commonly produced insect species for food and feed. Honeybee and silkworm are mostly produced for other reasons than as human food, yet we can still use them...... as examples to learn about emergence of new diseases in production insects. Results from a 2014 survey about insect diseases in current insect production systems are presented for the first time. Finally, we give some recommendations for the prevention and control of insect diseases. Key words: disease...

Remotely controlled large container disposal methodology

International Nuclear Information System (INIS)

Amir, S.J.

1994-09-01

Remotely Handled Large Containers (RHLC), also called drag-off boxes, have been used at the Hanford Site since the 1940s to dispose of large pieces of radioactively contaminated equipment. These containers are typically large steel-reinforced concrete boxes, which weigh as much as 40 tons. Because large quantities of high-dose waste can produce radiation levels as high as 200 mrem/hour at 200 ft, the containers are remotely handled (either lifted off the railcar by crane or dragged off with a cable). Many of the existing containers do not meet existing structural and safety design criteria and some of the transportation requirements. The drag-off method of pulling the box off the railcar using a cable and a tractor is also not considered a safe operation, especially in view of past mishaps

Production of High Quality Die Steels from Large ESR Slab Ingots

Science.gov (United States)

Geng, Xin; Jiang, Zhou-hua; Li, Hua-bing; Liu, Fu-bin; Li, Xing

With the rapid development of manufacture industry in China, die steels are in great need of large slab ingot of high quality and large tonnage, such as P20, WSM718R and so on. Solidification structure and size of large slab ingots produced with conventional methods are not satisfied. However, large slab ingots manufactured by ESR process have a good solidification structure and enough section size. In the present research, the new slab ESR process was used to produce the die steels large slab ingots with the maximum size of 980×2000×3200mm. The compact and sound ingot can be manufactured by the slab ESR process. The ultra-heavy plates with the maximum thickness of 410 mm can be obtained after rolling the 49 tons ingots. Due to reducing the cogging and forging process, the ESR for large slab ingots process can increase greatly the yield and production efficiency, and evidently cut off product costs.

Barium in produced water: Is it a toxicological hazard to the marine environment?

International Nuclear Information System (INIS)

Neff, J.M.

1993-01-01

Produced water is a complex aqueous mixture of organic and inorganic chemicals that often is generated in large volumes as a by-product of production of oil and gas. Produced water from offshore oil production platforms sometimes is treated to remove particulate oil and then discharged to the ocean. Barium often is the most abundant inorganic chemical, other than the dominant sea salts, in produced water. Some concern has been expressed that the large amounts of barium discharged to the ocean in produced water may have adverse effects on marine biological communities. The ecological risks associated with discharge to the ocean in produced water may have adverse effects on marine biological communities. The ecological risks associated with discharge to the ocean of barium in produced water were evaluated. Concentrations of barium in produced water from different sources range from less than 1.0 to about 2,000 mg/L, and are inversely correlated with concentrations of sulfate. Concentrations of barium in the ocean usually are in the range of 10 to 20 μg/L; the ocean is undersaturated with respect to barite (BaSO 4 ). During mixing and dilution of a produced water plume in the ocean, barium reacts with the abundant sulfate in seawater and precipitates as barite. Barite is completely nontoxic to marine organisms. Because of the high concentration of sulfate in the ocean, ionic barium can not reach concentrations high enough to be toxic to marine organisms

[Morphological characteristics and physiological properties of aflatoxin B1 producing and non-producing Aspergillus flavus strains].

Science.gov (United States)

Kogbo, W; Lemarinier, S; Boutibonnes, P

1985-09-01

Comparison between about 80 strains of Aspergillus flavus, belonging to the series flavus and oryzae, obtained from international collections but also isolated from French or African substrates revealed the following observations: 1. Cultural and morphological characteristics of toxicogenic and atoxicogenic strains of A. flavus are similar. However, the former produce a diffusible yellow pigment in 83% of isolates. 2. The two groups of conidiospores have the same resistance to UV irradiation (254 nm, 5 and 10 min). All the strains are equally sensitive to 4 antifungal antibiotics: nystatine, ketoconazole, clotrimazole and amphotericine. 3. A difference was seen in the capacity to produce enzymes as alpha-galactosidase, beta-galactosidase and beta-glucosidase, implicated in the glucid metabolism. The specific hydrolytic activity has been confirmed by the characterization of a large amount of beta-galactosidase and by a diauxic growth on glucose medium supplemented by lactose. Possible relationship between these characters and aflatoxin B1 production by A. flavus strains is discussed.

Produced water radionuclide hazard/risk assessment, Phase 1

Energy Technology Data Exchange (ETDEWEB)

Hamilton, L.D.; Meinhold, A.F.; Nagy, J.

1991-06-01

Petroleum production may be accompanied by the production of saline water, called produced water.'' Produced water discharged into freshwater streams, estuaries, coastal and outer continental shelf waters can contained enhanced levels of radium isotopes. This document reports on the first phase of a study to estimate the risk to human health and the environment from radium discharged in produced water. The study involved five major steps: (1) evaluate the usefulness of available produced water outfall data for developing estimates of radium environmental concentrations; (2) review the literature on the bioaccumulation of radium by aquatic organism; (3) review the literature on the effects of radiation on aquatic organisms; (4) review the information available concerning the human health risks associated with exposure to Ra-226 and Ra-228 and (5) perform a conservative, screening-level assessment of the health and environmental risks posed by Ra-226 and Ra-228 discharged in produced waters. A screening-level analysis was performed to determine whether radium discharged to coastal Louisiana in produced waters presents potential health or environmental risks requiring further study. This conservative assessment suggested that no detectable impact on populations of fish, molluscs or crustaceans from radium discharged in produced waters is likely. The analysis also suggested that there is a potential for risk were an individual to ingest a large amount of seafood harvested near a produced water discharge point over a lifetime. The number of excess cancers predicted per year under a conservative scenario is comparable to those expected to result from background concentrations of radium.

Produced water radionuclide hazard/risk assessment, Phase 1

Energy Technology Data Exchange (ETDEWEB)

Hamilton, L.D.; Meinhold, A.F.; Nagy, J.

1991-06-01

Petroleum production may be accompanied by the production of saline water, called ``produced water.`` Produced water discharged into freshwater streams, estuaries, coastal and outer continental shelf waters can contained enhanced levels of radium isotopes. This document reports on the first phase of a study to estimate the risk to human health and the environment from radium discharged in produced water. The study involved five major steps: (1) evaluate the usefulness of available produced water outfall data for developing estimates of radium environmental concentrations; (2) review the literature on the bioaccumulation of radium by aquatic organism; (3) review the literature on the effects of radiation on aquatic organisms; (4) review the information available concerning the human health risks associated with exposure to Ra-226 and Ra-228 and (5) perform a conservative, screening-level assessment of the health and environmental risks posed by Ra-226 and Ra-228 discharged in produced waters. A screening-level analysis was performed to determine whether radium discharged to coastal Louisiana in produced waters presents potential health or environmental risks requiring further study. This conservative assessment suggested that no detectable impact on populations of fish, molluscs or crustaceans from radium discharged in produced waters is likely. The analysis also suggested that there is a potential for risk were an individual to ingest a large amount of seafood harvested near a produced water discharge point over a lifetime. The number of excess cancers predicted per year under a conservative scenario is comparable to those expected to result from background concentrations of radium.

Produced water radionuclide hazard/risk assessment, Phase 1

International Nuclear Information System (INIS)

Hamilton, L.D.; Meinhold, A.F.; Nagy, J.

1991-06-01

Petroleum production may be accompanied by the production of saline water, called ''produced water.'' Produced water discharged into freshwater streams, estuaries, coastal and outer continental shelf waters can contained enhanced levels of radium isotopes. This document reports on the first phase of a study to estimate the risk to human health and the environment from radium discharged in produced water. The study involved five major steps: (1) evaluate the usefulness of available produced water outfall data for developing estimates of radium environmental concentrations; (2) review the literature on the bioaccumulation of radium by aquatic organism; (3) review the literature on the effects of radiation on aquatic organisms; (4) review the information available concerning the human health risks associated with exposure to Ra-226 and Ra-228 and (5) perform a conservative, screening-level assessment of the health and environmental risks posed by Ra-226 and Ra-228 discharged in produced waters. A screening-level analysis was performed to determine whether radium discharged to coastal Louisiana in produced waters presents potential health or environmental risks requiring further study. This conservative assessment suggested that no detectable impact on populations of fish, molluscs or crustaceans from radium discharged in produced waters is likely. The analysis also suggested that there is a potential for risk were an individual to ingest a large amount of seafood harvested near a produced water discharge point over a lifetime. The number of excess cancers predicted per year under a conservative scenario is comparable to those expected to result from background concentrations of radium

Don't Cry over Spilled Water: Identifying Risks and Solutions for Produced Water Spills

Science.gov (United States)

Shores, Amanda Rose

Resource requirements and future energy generation requires careful evaluation, particularly due to climate change and water scarcity. This thesis discusses one aspect of energy generation linked to water; oil-and-gas extraction and the large volumes of waste water produced, otherwise known as "produced water". This research focuses on surface spills of produced water, their ramifications, safeguards against groundwater contamination at spill sites and potential remediation strategies. Produced water contains a variety of contaminants that include the group of known toxins, BTEX (benzene, toluene, ethylbenzene and xylene), and high salt concentrations. A combination of factors such as large volumes of generated produced water, the need for storage and transportation across large distances and the toxic-and-mobile nature of produced water constituents creates risks for spills that can pollute groundwater. Spills occur regularly, particularly in Weld County, Colorado, where the demand for natural gas is high. To answer spill-related hypotheses, a multitude of methodology were employed: modeling, greenhouse experimentation, gas chromatography and summarization of spill reports and statistical analyses. Using publically available spill data, this research found that the frequency of oil-and-gas related spills and the average spilled volume has increased in Weld County from 2011-2015. Additionally, the number of spills that have resulted in groundwater contamination has increased in the area. By focusing on the oil-and-gas operators responsible for these spills, a linear relationship was found between the volumes of oil-and-gas produced compared to the volumes of produced-water generated. However, larger oil-and-gas producers did not show a linear relationship between oil-and-gas produced and produced-water generated, such that larger producers were more efficient and generated less water per unit of energy. So while scale-up efficiency seems to exist for produced

Multiscale Aspects of the Storm Producing the June 2013 Flooding in Uttarakhand, India

Energy Technology Data Exchange (ETDEWEB)

Houze, R. A. [Department of Atmospheric Sciences, University of Washington, Seattle, and Pacific Northwest National Laboratory, Richland, Washington; McMurdie, L. A. [Department of Atmospheric Sciences, University of Washington, Seattle, Washington; Rasmussen, K. L. [Department of Atmospheric Science, Colorado State University, Fort Collins, Colorado; Kumar, A. [NASA Goddard Space Flight Center, Greenbelt, and Earth System Science Interdisciplinary Center, University of Maryland, College Park, College Park, Maryland; Chaplin, M. M. [Department of Atmospheric Sciences, University of Washington, Seattle, Washington

2017-11-01

Conditions producing disastrous flooding in Uttarakhand, India, in June 2013 differed from conditions that produced other notorious floods in the Himalayan region in recent years. During the week preceding the Uttarakhand flood, deep convection moistened the mountainsides, making them vulnerable to flooding. However, the precipitation producing the flood was not associated with a deep convective event. Rather, an eastward-propagating upper-level trough in the westerlies extended abnormally far southward, with the jet reaching the Himalayas. The south end of the trough merged with a monsoon low moving westward across India. The merged system produced persistent moist low-level flow oriented normal to the Himalayas that advected large amounts of water vapor into the Uttarakhand region. The flow was moist neutral when it passed over the Himalayan barrier, and orographic lifting produced heavy continuous rain over the region for 2–3 days. The precipitation was largely stratiform in nature although embedded convection of moderate depth occurred along the foothills, where some mild instability was being released. The Uttarakhand flood had characteristics in common with major 2013 floods in the Rocky Mountains in Colorado and Alberta, Canada.

Isolation of protease producing novel Bacillus cereus and detection ...

African Journals Online (AJOL)

user

2011-02-14

Feb 14, 2011 ... The highest protease activity was determined at 30°C temperature and 6.4 pH conditions and after the 18th hour, it decreased evidently. Key words: Protease, production, optimization, Bacillus sp. INTRODUCTION. Enzymes have been produced in large industrial scale for several decades (Falch, 1991).

Degree-days as a tool for use in producing tilapia fry for sex inversion

Science.gov (United States)

Hormonal sex inversion of newly hatched tilapia fry continues to be an important method to produce monosex male tilapia fingerlings. Large numbers of tilapia fry suitable for sex inversion can be produced by periodic complete harvest of earthen reproduction ponds. Traditionally, harvest interval was...

Vortex-ring-induced large bubble entrainment during drop impact

KAUST Repository

Thoraval, Marie-Jean

2016-03-29

For a limited set of impact conditions, a drop impacting onto a pool can entrap an air bubble as large as its own size. The subsequent rise and rupture of this large bubble plays an important role in aerosol formation and gas transport at the air-sea interface. The large bubble is formed when the impact crater closes up near the pool surface and is known to occur only for drops that are prolate at impact. Herein we use experiments and numerical simulations to show that a concentrated vortex ring, produced in the neck between the drop and the pool, controls the crater deformations and pinchoff. However, it is not the strongest vortex rings that are responsible for the large bubbles, as they interact too strongly with the pool surface and self-destruct. Rather, it is somewhat weaker vortices that can deform the deeper craters, which manage to pinch off the large bubbles. These observations also explain why the strongest and most penetrating vortex rings emerging from drop impacts are not produced by oblate drops but by more prolate drop shapes, as had been observed in previous experiments.

A novel method for producing multiple ionization of noble gas

International Nuclear Information System (INIS)

Wang Li; Li Haiyang; Dai Dongxu; Bai Jiling; Lu Richang

1997-01-01

We introduce a novel method for producing multiple ionization of He, Ne, Ar, Kr and Xe. A nanosecond pulsed electron beam with large number density, which could be energy-controlled, was produced by incidence a focused 308 nm laser beam onto a stainless steel grid. On Time-of-Flight Mass Spectrometer, using this electron beam, we obtained multiple ionization of noble gas He, Ne, Ar and Xe. Time of fight mass spectra of these ions were given out. These ions were supposed to be produced by step by step ionization of the gas atoms by electron beam impact. This method may be used as a ideal soft ionizing point ion source in Time of Flight Mass Spectrometer

Isolation and characterization of large spectrum and multiple bacteriocin-producing Enterococcus faecium strain from raw bovine milk.

Science.gov (United States)

Gaaloul, N; ben Braiek, O; Hani, K; Volski, A; Chikindas, M L; Ghrairi, T

2015-02-01

To assess the antimicrobial properties of lactic acid bacteria from Tunisian raw bovine milk. A bacteriocin-producing Enterococcus faecium strain was isolated from raw cow milk with activity against Gram-positive and Gram-negative bacteria. Antimicrobial substances produced by this strain were sensitive to proteolytic enzymes and were thermostable and resistant to a broad range of pH (2-10). Mode of action of antimicrobial substances was determined as bactericidal. Maximum activity was reached at the end of the exponential growth phase when checked against Listeria ivanovii BUG 496 (2366.62 AU ml(-1)). However, maximum antimicrobial activity against Pseudomonas aeruginosa 28753 was recorded at the beginning of the exponential growth phase. Enterococcus faecium GGN7 was characterized as free from virulence factors and was susceptible to tested antibiotics. PCR analysis of the micro-organism's genome revealed the presence of genes coding for enterocins A and B. Mass spectrometry analysis of RP-HPLC active fractions showed molecular masses corresponding to enterocins A (4835.77 Da) and B (5471.56 Da), and a peptide with a molecular mass of 3215.5 Da active only against Gram-negative indicator strains. The latter was unique in the databases. Enterococcus faecium GGN7 produces three bacteriocins with different inhibitory spectra. Based on its antimicrobial properties and safety, Ent. faecium GGN7 is potentially useful for food biopreservation. The results suggest the bacteriocins from GGN7 strain could be useful for food biopreservation. © 2014 The Society for Applied Microbiology.

Large-area perovskite nanowire arrays fabricated by large-scale roll-to-roll micro-gravure printing and doctor blading

Science.gov (United States)

Hu, Qiao; Wu, Han; Sun, Jia; Yan, Donghang; Gao, Yongli; Yang, Junliang

2016-02-01

Organic-inorganic hybrid halide perovskite nanowires (PNWs) show great potential applications in electronic and optoelectronic devices such as solar cells, field-effect transistors and photodetectors. It is very meaningful to fabricate ordered, large-area PNW arrays and greatly accelerate their applications and commercialization in electronic and optoelectronic devices. Herein, highly oriented and ultra-long methylammonium lead iodide (CH3NH3PbI3) PNW array thin films were fabricated by large-scale roll-to-roll (R2R) micro-gravure printing and doctor blading in ambient environments (humility ~45%, temperature ~28 °C), which produced PNW lengths as long as 15 mm. Furthermore, photodetectors based on these PNWs were successfully fabricated on both silicon oxide (SiO2) and flexible polyethylene terephthalate (PET) substrates and showed moderate performance. This study provides low-cost, large-scale techniques to fabricate large-area PNW arrays with great potential applications in flexible electronic and optoelectronic devices.Organic-inorganic hybrid halide perovskite nanowires (PNWs) show great potential applications in electronic and optoelectronic devices such as solar cells, field-effect transistors and photodetectors. It is very meaningful to fabricate ordered, large-area PNW arrays and greatly accelerate their applications and commercialization in electronic and optoelectronic devices. Herein, highly oriented and ultra-long methylammonium lead iodide (CH3NH3PbI3) PNW array thin films were fabricated by large-scale roll-to-roll (R2R) micro-gravure printing and doctor blading in ambient environments (humility ~45%, temperature ~28 °C), which produced PNW lengths as long as 15 mm. Furthermore, photodetectors based on these PNWs were successfully fabricated on both silicon oxide (SiO2) and flexible polyethylene terephthalate (PET) substrates and showed moderate performance. This study provides low-cost, large-scale techniques to fabricate large-area PNW arrays

Comparison of trends in abundance of guano-producing seabirds in ...

African Journals Online (AJOL)

The abundant guano-producing seabirds in Peru and southern Africa feed mainly on the large populations of anchovy Engraulis spp. and sardine Sardinops sagax supported by the Humboldt and Benguela upwelling systems. Numbers of guanay cormorants Phalacrocorax bougainvillii in Peru and the breeding population ...

Classification of low-resource livestock producers in the North West ...

African Journals Online (AJOL)

Unknown

Introduction. Inadequate nutrition is generally blamed for the low production of livestock within the holdings of low resource producers. This could partly be due to uncontrolled management of communal lands which are severely degraded and largely unproductive (Duvel & Sebina, 1998). Although much research attention ...

Emergence of ESBL-producing organisms in Mongolia

International Nuclear Information System (INIS)

Khosbayar, T.; Lkhamsuren, E.; Sop, C.Y.; Pak, C.Y.

2007-01-01

Full text: Extended spectrum β-lactamase is most commonly produced by strains of K.pneumoniae and E.coli, and TEM, SHV, CTX-M and AmpC types of the ESBLs are commonly spread among different nations. Previous investigators have already established that certain strains or ''epidemic clones'' of ESBL producing organisms spread within and also among hospitals. Although, some clones may disseminate regionally. Other authors emphasize the importance of plasmid transfer, rather than strain spread and plasmid encoding ESBL can transmit between different species of the family Enterobacteriaceae. The genes encoding these β-lactamases are often located on large plasmids that also encode genes for resistance to other antibiotics, including aminoglycosides, tetracycline, sulfonamides, trimethoprim and chloramphenicol. Furthermore, there is an increasing tendency for pathogens to produce multiple Β-lactamases. Some isolate of Klebsiella pneumoniae which is multiply resistant, expresses a minimum of five different β-lactamases, most of which are encoded on one large transferable plasmid. Materials and Methods: Nonrepetitive ESBL producing E. coli, K. pneumoniae and E.cloaceae isolates were collected in the bacteriology laboratory at Maternal and Child Research Institution, Ulaanbaatar (the biggest and central hospital facility for reproductive health service in Mongolia) in 2001, 2002, 2005, and 2006. Isolates were identified by conventional biochemical testing. Antimicrobial susceptibility were tested by disk diffusion test and MICs of some -lactams were determined alone or in combination with a fixed concentration of either clavulanic acid (2 μg/ml) according to the guideline of the National Committee for Clinical Laboratory Standards (NCCLS). ESBL production was screened using cefpodoxime disks and was confirmed by the double-disk synergy test. For detection of resistance transfer by conjugation, agar-mating technique was used with cultures of E.coli J53 Azir. PCRs with

Cefepime versus extended spectrum β-lactamase-producing Enterobacteriaceae

Directory of Open Access Journals (Sweden)

Keite da Silva Nogueira

Full Text Available The objective of this study was to evaluate the susceptibility to cefepime of a large group of ESBL- producing enterobacteria recently isolated in a Brazilian teaching hospital . The study included 280 strains of ESBL-producing enterobacteria, isolated between 2005 and 2008. The presence of the genes blaCTX-M, blaTEM and blaSHV was determined by PCR and confirmed by nucleotide sequencing. Susceptibility testing for cefepime was performed by disc-diffusion, agar dilution method and E-test®. Among the isolates, 34 (12.1% presented a cefepime inhibition zone > 21 and MIC < 8 mg/L by agar dilution and E-strip methods. The use of cefepime for the treatment of infections caused by ESBL-producing bacteria has been controversial. Some studies of PD/PK show the probability of achieving the required PD parameters for cefepime, when the MICs were < 8 mg/L, whereas others have reported therapeutic failure with the same MIC. Additional data is essential to come to terms about the report and treatment with cefepime in ESBL-producing organisms especially when these microorganisms are isolated from sterile sites and from critically ill patients.

New Applications of Electrochemically Produced Porous Semiconductors and Nanowire Arrays

Directory of Open Access Journals (Sweden)

Leisner Malte

2010-01-01

Full Text Available Abstract The growing demand for electro mobility together with advancing concepts for renewable energy as primary power sources requires sophisticated methods of energy storage. In this work, we present a Li ion battery based on Si nanowires, which can be produced reliable and cheaply and which shows superior properties, such as a largely increased capacity and cycle stability. Sophisticated methods based on electrochemical pore etching allow to produce optimized regular arrays of nanowires, which can be stabilized by intrinsic cross-links, which serve to avoid unwanted stiction effects and allow easy processing.

Development of device producing electrolyzed water for home care

International Nuclear Information System (INIS)

Umimoto, K; Nagata, S; Yanagida, J

2013-01-01

When water containing ionic substances is electrolyzed, electrolyzed water with strong bactericidal ability due to the available chlorine(AC) is generated on the anode side. Slightly acidic to neutral electrolyzed water (pH 6.5 to 7.5) is physiological pH and is suitable for biological applications. For producing slightly acidic to neutral electrolyzed water simply, a vertical-type electrolytic tank with an asymmetric structure was made. As a result, a small amount of strongly alkaline water was generated in the upper cathodic small chamber, and a large amount of weakly acidic water generated in the lower anodic large chamber. The pH and AC concentration in solutin mixed with both electrolyzed water were 6.3 and 39.5 ppm, respectively, This solution was slightly acidic to neutral electrolyzed water and had strong bactericidal activity. This device is useful for producing slightly acidic to neutral electrolyzed water as a disinfectant to employ at home care, when considering economic and environmental factors, since it returns to ordinary water after use.

An efficient and novel computation method for simulating diffraction patterns from large-scale coded apertures on large-scale focal plane arrays

Science.gov (United States)

Shrekenhamer, Abraham; Gottesman, Stephen R.

2012-10-01

A novel and memory efficient method for computing diffraction patterns produced on large-scale focal planes by largescale Coded Apertures at wavelengths where diffraction effects are significant has been developed and tested. The scheme, readily implementable on portable computers, overcomes the memory limitations of present state-of-the-art simulation codes such as Zemax. The method consists of first calculating a set of reference complex field (amplitude and phase) patterns on the focal plane produced by a single (reference) central hole, extending to twice the focal plane array size, with one such pattern for each Line-of-Sight (LOS) direction and wavelength in the scene, and with the pattern amplitude corresponding to the square-root of the spectral irradiance from each such LOS direction in the scene at selected wavelengths. Next the set of reference patterns is transformed to generate pattern sets for other holes. The transformation consists of a translational pattern shift corresponding to each hole's position offset and an electrical phase shift corresponding to each hole's position offset and incoming radiance's direction and wavelength. The set of complex patterns for each direction and wavelength is then summed coherently and squared for each detector to yield a set of power patterns unique for each direction and wavelength. Finally the set of power patterns is summed to produce the full waveband diffraction pattern from the scene. With this tool researchers can now efficiently simulate diffraction patterns produced from scenes by large-scale Coded Apertures onto large-scale focal plane arrays to support the development and optimization of coded aperture masks and image reconstruction algorithms.

Seasonal variation in the environmental background level of cosmic ray produced 22Na

International Nuclear Information System (INIS)

Tokuyama, Hideki; Igarashi, Shuichi

1998-01-01

22 Na (half life 2.6 year) is produced by cosmic rays, nuclear test and reactor. 7 Be (half life 53.3 day) is produced in atmosphere by reaction. 7 Be/ 22 Na activity ratio is good factor to observe the mixing process between stratosphere and troposphere atmosphere. The seasonal variation of 7 Be and 22 Na deposition, the ratio and the background level of 22 Na deposition were observed in Fukui city and reported in this paper. Very large reasonable change of 22 Na deposition was observed, especially the largest peak in winter. Because the concentration of cosmic-ray-produced nuclear in precipitation and the amount of precipitation were large in winter. 22 Na produced by the previous nuclear test was attenuated. The present 22 Na is only produced by cosmic rays, indicating the background level. 22 Na deposition at Fukui was 0.42Bq m -2 y -1 , one ten-thousandth of 7 Be deposition. 7 Be/ 22 Na activity ratio was changed in season and the largest peak was shown in autumn. In this reason, atmosphere showed relatively short residence time in the lower part of stratosphere, Mixture and exchange of atmosphere between stratosphere and troposphere were the most active in autumn. (S.Y.)

Large area solid target neutron source

International Nuclear Information System (INIS)

Crawford, J.C.; Bauer, W.

1974-01-01

A potentially useful neutron source may result from the combination of a solid deuterium-tritium loaded target with the large area, high energy ion beams from ion sources being developed for neutral beam injection. The resulting neutron source would have a large radiating area and thus produce the sizable experimental volume necessary for future studies of bulk and synergistic surface radiation effects as well as experiments on engineering samples and small components. With a 200 keV D + T + beam and 40 kW/cm 2 power dissipation on a 200 cm 2 target spot, a total neutron yield of about 4 x 10 15 n/sec may be achieved. Although the useable neutron flux from this source is limited to 1 to 2 x 10 13 n/cm 2 /sec, this flux can be produced 3 cm in front of the target and over about 300 cm 3 of experimental volume. Problems of total power dissipation, sputtering, isotopic flushing and thermal dissociation are reviewed. Neutron flux profiles and potential experimental configurations are presented and compared to other neutron source concepts. (U.S.)

Talaromyces atroroseus, a new species efficiently producing industrially relevant red pigments

DEFF Research Database (Denmark)

Frisvad, Jens Christian; Yilmaz, Neriman; Thrane, Ulf

2013-01-01

., described in this study, produces the azaphilone biosynthetic families mitorubrins and Monascus pigments without any production of mycotoxins. Within the red pigment producing clade, T. atroroseus resolved in a distinct clade separate from all the other species in multigene phylogenies (ITS, β......Some species of Talaromyces secrete large amounts of red pigments. Literature has linked this character to species such as Talaromyces purpurogenus, T. albobiverticillius, T. marneffei, and T. minioluteus often under earlier Penicillium names. Isolates identified as T. purpurogenus have been...... reported to be interesting industrially and they can produce extracellular enzymes and red pigments, but they can also produce mycotoxins such as rubratoxin A and B and luteoskyrin. Production of mycotoxins limits the use of isolates of a particular species in biotechnology. Talaromyces atroroseus sp. nov...

Stabilization Algorithms for Large-Scale Problems

DEFF Research Database (Denmark)

Jensen, Toke Koldborg

2006-01-01

The focus of the project is on stabilization of large-scale inverse problems where structured models and iterative algorithms are necessary for computing approximate solutions. For this purpose, we study various iterative Krylov methods and their abilities to produce regularized solutions. Some......-curve. This heuristic is implemented as a part of a larger algorithm which is developed in collaboration with G. Rodriguez and P. C. Hansen. Last, but not least, a large part of the project has, in different ways, revolved around the object-oriented Matlab toolbox MOORe Tools developed by PhD Michael Jacobsen. New...

Exploring the large-scale structure of Taylor–Couette turbulence through Large-Eddy Simulations

Science.gov (United States)

Ostilla-Mónico, Rodolfo; Zhu, Xiaojue; Verzicco, Roberto

2018-04-01

Large eddy simulations (LES) of Taylor-Couette (TC) flow, the flow between two co-axial and independently rotating cylinders are performed in an attempt to explore the large-scale axially-pinned structures seen in experiments and simulations. Both static and dynamic LES models are used. The Reynolds number is kept fixed at Re = 3.4 · 104, and the radius ratio η = ri /ro is set to η = 0.909, limiting the effects of curvature and resulting in frictional Reynolds numbers of around Re τ ≈ 500. Four rotation ratios from Rot = ‑0.0909 to Rot = 0.3 are simulated. First, the LES of TC is benchmarked for different rotation ratios. Both the Smagorinsky model with a constant of cs = 0.1 and the dynamic model are found to produce reasonable results for no mean rotation and cyclonic rotation, but deviations increase for increasing rotation. This is attributed to the increasing anisotropic character of the fluctuations. Second, “over-damped” LES, i.e. LES with a large Smagorinsky constant is performed and is shown to reproduce some features of the large-scale structures, even when the near-wall region is not adequately modeled. This shows the potential for using over-damped LES for fast explorations of the parameter space where large-scale structures are found.

VESPA: Very large-scale Evolutionary and Selective Pressure Analyses

Directory of Open Access Journals (Sweden)

Andrew E. Webb

2017-06-01

Full Text Available Background Large-scale molecular evolutionary analyses of protein coding sequences requires a number of preparatory inter-related steps from finding gene families, to generating alignments and phylogenetic trees and assessing selective pressure variation. Each phase of these analyses can represent significant challenges, particularly when working with entire proteomes (all protein coding sequences in a genome from a large number of species. Methods We present VESPA, software capable of automating a selective pressure analysis using codeML in addition to the preparatory analyses and summary statistics. VESPA is written in python and Perl and is designed to run within a UNIX environment. Results We have benchmarked VESPA and our results show that the method is consistent, performs well on both large scale and smaller scale datasets, and produces results in line with previously published datasets. Discussion Large-scale gene family identification, sequence alignment, and phylogeny reconstruction are all important aspects of large-scale molecular evolutionary analyses. VESPA provides flexible software for simplifying these processes along with downstream selective pressure variation analyses. The software automatically interprets results from codeML and produces simplified summary files to assist the user in better understanding the results. VESPA may be found at the following website: http://www.mol-evol.org/VESPA.

Screening concepts for the isolation of biosurfactant producing microorganisms.

Science.gov (United States)

Walter, Vanessa; Syldatk, Christoph; Hausmann, Rudolf

2010-01-01

This chapter gives an overview of current methods for the isolation of biosurfactant producing microbes. The common screening methods for biosurfactants are presented. Sampling and isolation of bacteria are the basis for screening of biosurfactant producing microbes. Hydrocarbon-contaminated sites are the most promising for the isolation of biosurfactant producing microbes, but many strains have also been isolated from undisturbed sites. In subsequent steps the isolates have to be characterized in order to identify the strains which are interesting for a further investigation. Several techniques have been developed for identifying biosurfactant producing strains. Most of them are directly based on the surface or interfacial activity of the culture supernatant. Apart from that, some screening methods explore the hydrophobicity of the cell surface. This trait also gives an indication on biosurfactant production. In recent years automation and miniaturization have led to the development of high throughput methods for screening. High throughput screening (HTS) for analyzing large amounts of potential candidates or whole culture collections is reflected in the end. However, no new principals have been introduced by HTS methods.

Test of models for electron transport in laser produced plasmas

International Nuclear Information System (INIS)

Colombant, D.G.; Manheimer, W.M.; Busquet, M.

2005-01-01

This paper examines five different models of electron thermal transport in laser produced spherical implosions. These are classical, classical with a flux limit f, delocalization, beam deposition model, and Fokker-Planck solutions. In small targets, the results are strongly dependent on f for flux limit models, with small f's generating very steep temperature gradients. Delocalization models are characterized by large preheat in the center of the target. The beam deposition model agrees reasonably well with the Fokker-Planck simulation results. For large, high gain fusion targets, the delocalization model shows the gain substantially reduced by the preheat. However, flux limitation models show gain largely independent of f, with the beam deposition model also showing the same high gain

THE 'TWIN-CME' SCENARIO AND LARGE SOLAR ENERGETIC PARTICLE EVENTS IN SOLAR CYCLE 23

International Nuclear Information System (INIS)

Ding, Liuguan; Jiang, Yong; Zhao, Lulu; Li, Gang

2013-01-01

Energetic particles in large solar energetic particle (SEP) events are a major concern for space weather. Recently, Li et al. proposed a 'twin-CME' scenario for ground-level events. Here we extend that study to large SEP events in solar cycle 23. Depending on whether preceding coronal mass ejections (CMEs) within 9 hr exist and whether ions >10 MeV nucleon –1 exceed 10 pfu, we categorize fast CMEs with speed >900 km s –1 and width >60° from the western hemisphere source regions into four groups: groups I and II are 'twin' and single CMEs that lead to large SEPs; groups III and IV are 'twin' and single CMEs that do not lead to large SEPs. The major findings of this paper are: first, large SEP events tend to be 'twin-CME' events. Of 59 western large SEP events in solar cycle 23, 43 are 'twin-CME' (group I) events and 16 are single-CME (group II) events. Second, not all 'twin CMEs' produced large SEPs: 28 twin CMEs did not produce large SEPs (group III events). Some of them produced excesses of particles up to a few MeV nucleon –1 . Third, there were 39 single fast CMEs that did not produce SEPs (group IV events). Some of these also showed an excess of particles up to a few MeV nucleon –1 . For all four groups of events, we perform statistical analyses on properties such as the angular width, the speed, the existence of accompanying metric type II radio bursts, and the associated flare class for the main CMEs and the preceding CMEs.

Reproducible, large-scale production of thallium-based high-temperature superconductors

International Nuclear Information System (INIS)

Gay, R.L.; Stelman, D.; Newcomb, J.C.; Grantham, L.F.; Schnittgrund, G.D.

1990-01-01

This paper reports on the development of a large scale spray-calcination technique generic to the preparation of ceramic high-temperature superconductor (HTSC) powders. Among the advantages of the technique is that of producing uniformly mixed metal oxides on a fine scale. Production of both yttrium and thallium-based HTSCs has been demonstrated using this technique. In the spray calciner, solutions of the desired composition are atomized as a fine mist into a hot gas. Evaporation and calcination are instantaneous, yielding an extremely fine, uniform oxide powder. The calciner is 76 cm in diameter and can produce metal oxide powder at relatively large rates (approximately 100 g/h) without contamination

Production of a large, quiescent, magnetized plasma

Science.gov (United States)

Landt, D. L.; Ajmera, R. C.

1976-01-01

An experimental device is described which produces a large homogeneous quiescent magnetized plasma. In this device, the plasma is created in an evacuated brass cylinder by ionizing collisions between electrons emitted from a large-diameter electron gun and argon atoms in the chamber. Typical experimentally measured values of the electron temperature and density are presented which were obtained with a glass-insulated planar Langmuir probe. It is noted that the present device facilitates the study of phenomena such as waves and diffusion in magnetized plasmas.

Large-scale production of lentiviral vector in a closed system hollow fiber bioreactor

Directory of Open Access Journals (Sweden)

Jonathan Sheu

Full Text Available Lentiviral vectors are widely used in the field of gene therapy as an effective method for permanent gene delivery. While current methods of producing small scale vector batches for research purposes depend largely on culture flasks, the emergence and popularity of lentiviral vectors in translational, preclinical and clinical research has demanded their production on a much larger scale, a task that can be difficult to manage with the numbers of producer cell culture flasks required for large volumes of vector. To generate a large scale, partially closed system method for the manufacturing of clinical grade lentiviral vector suitable for the generation of induced pluripotent stem cells (iPSCs, we developed a method employing a hollow fiber bioreactor traditionally used for cell expansion. We have demonstrated the growth, transfection, and vector-producing capability of 293T producer cells in this system. Vector particle RNA titers after subsequent vector concentration yielded values comparable to lentiviral iPSC induction vector batches produced using traditional culture methods in 225 cm2 flasks (T225s and in 10-layer cell factories (CF10s, while yielding a volume nearly 145 times larger than the yield from a T225 flask and nearly three times larger than the yield from a CF10. Employing a closed system hollow fiber bioreactor for vector production offers the possibility of manufacturing large quantities of gene therapy vector while minimizing reagent usage, equipment footprint, and open system manipulation.

Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon.

Directory of Open Access Journals (Sweden)

Seong Gyu Jeon

Full Text Available Specific intestinal microbiota has been shown to induce Foxp3(+ regulatory T cell development. However, it remains unclear how development of another regulatory T cell subset, Tr1 cells, is regulated in the intestine. Here, we analyzed the role of two probiotic strains of intestinal bacteria, Lactobacillus casei and Bifidobacterium breve in T cell development in the intestine. B. breve, but not L. casei, induced development of IL-10-producing Tr1 cells that express cMaf, IL-21, and Ahr in the large intestine. Intestinal CD103(+ dendritic cells (DCs mediated B. breve-induced development of IL-10-producing T cells. CD103(+ DCs from Il10(-/-, Tlr2(-/-, and Myd88(-/- mice showed defective B. breve-induced Tr1 cell development. B. breve-treated CD103(+ DCs failed to induce IL-10 production from co-cultured Il27ra(-/- T cells. B. breve treatment of Tlr2(-/- mice did not increase IL-10-producing T cells in the colonic lamina propria. Thus, B. breve activates intestinal CD103(+ DCs to produce IL-10 and IL-27 via the TLR2/MyD88 pathway thereby inducing IL-10-producing Tr1 cells in the large intestine. Oral B. breve administration ameliorated colitis in immunocompromised mice given naïve CD4(+ T cells from wild-type mice, but not Il10(-/- mice. These findings demonstrate that B. breve prevents intestinal inflammation through the induction of intestinal IL-10-producing Tr1 cells.

Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon.

Science.gov (United States)

Jeon, Seong Gyu; Kayama, Hisako; Ueda, Yoshiyasu; Takahashi, Takuya; Asahara, Takashi; Tsuji, Hirokazu; Tsuji, Noriko M; Kiyono, Hiroshi; Ma, Ji Su; Kusu, Takashi; Okumura, Ryu; Hara, Hiromitsu; Yoshida, Hiroki; Yamamoto, Masahiro; Nomoto, Koji; Takeda, Kiyoshi

2012-01-01

Specific intestinal microbiota has been shown to induce Foxp3(+) regulatory T cell development. However, it remains unclear how development of another regulatory T cell subset, Tr1 cells, is regulated in the intestine. Here, we analyzed the role of two probiotic strains of intestinal bacteria, Lactobacillus casei and Bifidobacterium breve in T cell development in the intestine. B. breve, but not L. casei, induced development of IL-10-producing Tr1 cells that express cMaf, IL-21, and Ahr in the large intestine. Intestinal CD103(+) dendritic cells (DCs) mediated B. breve-induced development of IL-10-producing T cells. CD103(+) DCs from Il10(-/-), Tlr2(-/-), and Myd88(-/-) mice showed defective B. breve-induced Tr1 cell development. B. breve-treated CD103(+) DCs failed to induce IL-10 production from co-cultured Il27ra(-/-) T cells. B. breve treatment of Tlr2(-/-) mice did not increase IL-10-producing T cells in the colonic lamina propria. Thus, B. breve activates intestinal CD103(+) DCs to produce IL-10 and IL-27 via the TLR2/MyD88 pathway thereby inducing IL-10-producing Tr1 cells in the large intestine. Oral B. breve administration ameliorated colitis in immunocompromised mice given naïve CD4(+) T cells from wild-type mice, but not Il10(-/-) mice. These findings demonstrate that B. breve prevents intestinal inflammation through the induction of intestinal IL-10-producing Tr1 cells.

The new allelic variant of the subtilase cytotoxin (subAB2) is common among Shiga toxin-producing Escherichia coli strains from large game animals and their meat and meat products.

Science.gov (United States)

Sánchez, Sergio; Díaz-Sánchez, Sandra; Martínez, Remigio; Llorente, María Teresa; Herrera-León, Silvia; Vidal, Dolors

2013-10-25

Subtilase cytotoxin (SubAB) is an AB5 toxin produced by Shiga toxin (Stx)-producing Escherichia coli (STEC) strains usually lacking the eae gene product intimin. Two allelic variants of SubAB encoding genes have been described: subAB1, located on a plasmid, and subAB2, located on a pathogenicity island (PAI) together with tia gene. While subAB1 has been reported to be more frequent among bovine strains, subAB2 has been mainly associated with strains from small ruminants. We investigated the presence of the two variants of subAB among 59 eae-negative STEC from large game animals (deer and wild boar) and their meat and meat products in order to assess the role of other species in the epidemiology of subAB-positive, eae-negative STEC. For this approach, the strains were PCR-screened for the presence of subAB, including the specific detection of both allelic variants, for the presence of saa, tia and sab, and for stx subtyping. Overall, subAB genes were detected in 71.2% of the strains: 84.1% of the strains from deer and 33.3% of the strains from wild boar. Most of them (97.6%) possessed subAB2 and most of these subAB2-positive strains (92.7%) were also positive for tia and negative for saa, suggesting the presence of the subAB2-harbouring PAI. Subtype stx2b was present in most of the strains (67.8%) and a statistically significant association could be established between subAB2 and stx2b. Our results suggest that large game animals, mainly deer, may represent an important animal reservoir of subAB2-positive, eae-negative STEC, and also highlight the risk of human infection posed by the consumption of large game meat and meat products. Copyright © 2013 Elsevier B.V. All rights reserved.

The impact of retailers own brand Fair Trade products on developing countries producers

DEFF Research Database (Denmark)

Aguiar, L. K.; Vieira, L. M.; Ferreira, G. C.

Fair Trade certification allows small producers to access international markets and to add value to their products. The Fair-Trade Labelling Organisation certification body (FLOCERT) is responsible for organising and transferring technical information from the consumer market to producers...... in developing countries. Fair trade certification reduces the complexity of transactions and enables producers to adhere to the certification system. FLOCERT exercises governance power in production sites to meet demand by the enforcement of the standards not dissimilar to what happens in global value chains....... Large food retailers have changed practices in the agro-food sector and opened markets to small producers from developing countries. Nevertheless, results reveal that certification imparts in high entry barriers in the form of the need for formal producers' associations, minimum export capacity...

Herbicidal potential of ophiobolins produced by Drechslera gigantea.

Science.gov (United States)

Evidente, Antonio; Andolfi, Anna; Cimmino, Alessio; Vurro, Maurizio; Fracchiolla, Mariano; Charudattan, Raghavan

2006-03-08

Drechslera gigantea, a potential mycoherbicide of grass weeds, was isolated in Florida from naturally infected large crabgrass (Digitaria sanguinalis); it produces phytotoxic metabolites in liquid culture. The main metabolite was identified by spectroscopic methods and optical properties as ophiobolin A (1), a well-known phytotoxic sesterterpene produced by several phytopathogenic fungi of important crops and already extensively studied for its interesting biological activities. The other three minor metabolites proved to be related to ophiobolin A and were identified using the same techniques as 6-epi-ophiobolin A and 3-anhydro-6-epi-ophiobolin A (2 and 3) and ophiobolin I (4). Assayed on punctured detached leaves of several grass and dicotyledon weeds, ophiobolin A proved to be on average more phytotoxic as compared to the other related compounds. Some structural features appear to be important for the phytoxicity, such as the hydroxy group at C-3, the stereochemistry at C-6, and the aldehyde group at C-7. Furthermore, grass weeds usually proved to be more sensitive to the phytotoxins than dicotyledons, on which ophiobolin A caused the appearance of large necrosis even at the lowest concentration assayed. This is the first report about the production of ophiobolins from D. gigantea and of the proposed use as potential natural herbicides against grass weeds.

Uptake of nourseothricin by the producing microorganism, Streptomyces noursei

International Nuclear Information System (INIS)

Roeder, B.; Graefe, U.

1985-01-01

The uptake of 14 C-(U)-nourseothricin by stationary phase mycelium of Streptomyces noursei JA 3890b-NG 13/14 was demonstrated. An energy-dependent transport system appears to be involved in the transport of the antibiotic. Relatively large quantities of the antibiotic were adsorbed to the surface of mycelium. Degradation of nourseothricin by the producing microorganism was not detectable. (author)

Large scale structure and baryogenesis

International Nuclear Information System (INIS)

Kirilova, D.P.; Chizhov, M.V.

2001-08-01

We discuss a possible connection between the large scale structure formation and the baryogenesis in the universe. An update review of the observational indications for the presence of a very large scale 120h -1 Mpc in the distribution of the visible matter of the universe is provided. The possibility to generate a periodic distribution with the characteristic scale 120h -1 Mpc through a mechanism producing quasi-periodic baryon density perturbations during inflationary stage, is discussed. The evolution of the baryon charge density distribution is explored in the framework of a low temperature boson condensate baryogenesis scenario. Both the observed very large scale of a the visible matter distribution in the universe and the observed baryon asymmetry value could naturally appear as a result of the evolution of a complex scalar field condensate, formed at the inflationary stage. Moreover, for some model's parameters a natural separation of matter superclusters from antimatter ones can be achieved. (author)

Performance Study of Dual Fuel Engine Using Producer Gas as Secondary Fuel

Directory of Open Access Journals (Sweden)

Deepika Shaw

2016-06-01

Full Text Available In the present paper, development of producer gas fuelled 4 stroke diesel engine has been investigated. Producer gas from biomass has been examined and successfully operated with 4 stroke diesel engine. The effects of higher and lower loads were investigated on the dual fuel mode. The experimental investigations revealed that at lower loads dual fuel operation with producer gas shows lower efficiency due to lower combustion rate cause by low calorific value of the producer gas. Beyond 40% load the brake thermal efficiency of dual fuel operation improved due to faster combustion rate of producer gas and higher level of premixing. It can be observed that at lower load and 20% opening of producer gas the gaseous fuel substitution found to be 56% whereas at 100% opening of producer gas it reaches 78% substitution. The CO2 emission increased at high producer gas opening and high load because at 100% producer gas maximum atoms of carbons were there and at high load condition the diesel use increased. At 80% load and producer gas varying from 20% to 100. Power output was almost comparable to diesel power with marginal higher efficiency. Producer gas is one such technology which is environmentally benign and holds large promise for future.

Large earthquakes and creeping faults

Science.gov (United States)

Harris, Ruth A.

2017-01-01

Faults are ubiquitous throughout the Earth's crust. The majority are silent for decades to centuries, until they suddenly rupture and produce earthquakes. With a focus on shallow continental active-tectonic regions, this paper reviews a subset of faults that have a different behavior. These unusual faults slowly creep for long periods of time and produce many small earthquakes. The presence of fault creep and the related microseismicity helps illuminate faults that might not otherwise be located in fine detail, but there is also the question of how creeping faults contribute to seismic hazard. It appears that well-recorded creeping fault earthquakes of up to magnitude 6.6 that have occurred in shallow continental regions produce similar fault-surface rupture areas and similar peak ground shaking as their locked fault counterparts of the same earthquake magnitude. The behavior of much larger earthquakes on shallow creeping continental faults is less well known, because there is a dearth of comprehensive observations. Computational simulations provide an opportunity to fill the gaps in our understanding, particularly of the dynamic processes that occur during large earthquake rupture and arrest.

CERN to start producing medical isotopes

CERN Document Server

Anaïs Schaeffer

2012-01-01

A promising project that was hailed at the ICTR-PHE 2012 medical conference (see Bulletin issues 10-11/2012 and 12-13/2012) has seen the light of day at CERN. The project, known by the name of MEDICIS, will make it possible to produce a large variety of radioactive isotopes for medical research.   This image of a brain, superimposed on a drawing by Leonardo da Vinci, was taken by a PET scanner after injecting a molecule containing a positron-emitting isotope. CERN-MEDICIS will produce new isotopes for imaging which will be able to show up cancerous tissues and destroy them by emitting local radiation as the isotopes decay. In the United States, a new radium-based drug which targets bone metastases is about to go on the market. Radium, which can be brought to bear at the cell level, is a potent weapon in the fight against certain types of cancer, and is opening the way to a new form of medicine. This is the direction that CERN has decided to follow through the CERN-MEDICIS* (Medical Isotopes...

Sideways Force Produced During Disruptions

Science.gov (United States)

Strauss, H. R.; Paccagnella, R.; Breslau, J.; Jardin, S.; Sugiyama, L.

2012-10-01

We extend previous studies [1] of vertical displacement events (VDE) which can produce disruptions. The emphasis is on the non axisymmetric ``sideways'' wall force Fx. Simulations are performed using the M3D [2] code. A VDE expels magnetic flux through the resistive wall until the last closed flux surface has q VDE is presented. The wall force depends strongly on γτw, where γ is the mode growth rate and τw is the wall resistive penetration time. The force Fx is largest when γτw is a constant of order unity, which depends on the initial conditions. For large values of γτw, the wall force asymptotes to a relatively smaller value, well below the critical value ITER is designed to withstand. The principle of disruption mitigation by massive gas injection is to cause a disruption with large γτw. [4pt] [1] H. R. Strauss, R. Paccagnella, and J. Breslau,Phys. Plasmas 17, 082505 (2010) [2] W. Park, E.V. Belova, G.Y. Fu, X. Tang, H.R. Strauss, L.E. Sugiyama, Phys. Plasmas 6, 1796 (1999).

Off-diagonal helicity density matrix elements for vector mesons produced at LEP

International Nuclear Information System (INIS)

Anselmino, M.; Bertini, M.; Quintairos, P.

1997-05-01

Final state q q-bar interactions may give origin to non zero values of the off-diagonal element ρ 1 of the helicity density matrix of vector mesons produced in e + e - annihilations, as confirmed by recent OPAL data on φ and D * 's. Predictions are given for ρ1,-1 of several mesons produced at large z and small PT, collinear with the parent jet; the values obtained for θ and D * are in agreement with data. (author)

A new approach to isolating siderophore-producing actinobacteria.

Science.gov (United States)

Nakouti, I; Sihanonth, P; Hobbs, G

2012-07-01

This study was conducted to investigate the application of 2,2'-dipyridyl as a new approach to isolating siderophore-producing actinobacteria. Isolation of actinobacteria from soil was conducted by a soil dilution plate technique using starch-casein agar. Iron starvation was fostered by the incorporation of the iron chelator 2,2'-dipyridyl in the isolation medium. Pretreatment of the samples at an elevated temperature (40°C) ensured that the majority of nonsporulating bacteria were excluded. The survivors of this treatment were largely actinobacteria. Of the viable cultures grown in the presence of 2,2'-dipyridyl, more than 78-88% (average of three separate studies) were reported to produce siderophore-like compounds compared to 13-18% (average of three separate studies) when grown on the basic media in the absence of the chelating agent. The most prolific producers as assessed by the chrome azurol sulphate (CAS) assay were further characterized and found to belong to the genus Streptomyces. Selective pressure using 2,2'-dipyridyl as an iron-chelating agent in starch-casein media increased the isolation of siderophore-producing actinobacteria compared to the unamended medium. The study described represents a new approach to the isolation of siderophore-producing actinobacteria using a novel procedure that places a selection on cell population based upon the incorporation of a chelating agent in the medium. © 2012 The Authors. Letters in Applied Microbiology © 2012 The Society for Applied Microbiology.

Dolichospermum and Aphanizomenon as neurotoxins producers in some Russian freshwaters.

Science.gov (United States)

Chernova, Ekaterina; Sidelev, Sergey; Russkikh, Iana; Voyakina, Ekaterina; Babanazarova, Olga; Romanov, Roman; Kotovshchikov, Anton; Mazur-Marzec, Hanna

2017-05-01

Last decades, cyanobacterial blooms have been commonly reported in Russia. Among the boom-forming species, potential toxin producers have been identified. The aim of this paper was to study the presence of neurotoxic compounds - saxitoxins and anatoxin-a - in water bodies from different regions of Russia. We also made attempts to identify the neurotoxin-producing genera. The good convergence of the results obtained by light microscopy, PCR and LC-MS/MS analyses indicated the presence of active neurotoxin producing species in all investigated water bodies. Saxitoxin was detected in phytoplankton from 4 water bodies in Central European Russia and West Siberia, including lake and reservoirs used as a source for potable water. The water bodies differed with the respect of saxitoxin producers which belonged to Aphanizomenon and/or Dolichospermum genera. For the first time, we obtained quantitative data on the intracellular saxitoxin concentration in Russian freshwaters using LC-MS/MS. Anatoxin-a was detected only in lakes of Northwestern Russia. In the eutrophic shallow Lower Suzdal Lake, Aphanizomenon was the stated anatoxin-a-producing genus. In the large shallow artificial hypertrophic Sestroretskij Razliv Lake, it was very likely that both dominant species - Aphanizomenon flos-aquae and Dolichospermum planctonicum - were anatoxin-a producers. Copyright © 2017 Elsevier Ltd. All rights reserved.

Large-Scale Structure and Hyperuniformity of Amorphous Ices

Science.gov (United States)

Martelli, Fausto; Torquato, Salvatore; Giovambattista, Nicolas; Car, Roberto

2017-09-01

We investigate the large-scale structure of amorphous ices and transitions between their different forms by quantifying their large-scale density fluctuations. Specifically, we simulate the isothermal compression of low-density amorphous ice (LDA) and hexagonal ice to produce high-density amorphous ice (HDA). Both HDA and LDA are nearly hyperuniform; i.e., they are characterized by an anomalous suppression of large-scale density fluctuations. By contrast, in correspondence with the nonequilibrium phase transitions to HDA, the presence of structural heterogeneities strongly suppresses the hyperuniformity and the system becomes hyposurficial (devoid of "surface-area fluctuations"). Our investigation challenges the largely accepted "frozen-liquid" picture, which views glasses as structurally arrested liquids. Beyond implications for water, our findings enrich our understanding of pressure-induced structural transformations in glasses.

Large Scale Processes and Extreme Floods in Brazil

Science.gov (United States)

Ribeiro Lima, C. H.; AghaKouchak, A.; Lall, U.

2016-12-01

Persistent large scale anomalies in the atmospheric circulation and ocean state have been associated with heavy rainfall and extreme floods in water basins of different sizes across the world. Such studies have emerged in the last years as a new tool to improve the traditional, stationary based approach in flood frequency analysis and flood prediction. Here we seek to advance previous studies by evaluating the dominance of large scale processes (e.g. atmospheric rivers/moisture transport) over local processes (e.g. local convection) in producing floods. We consider flood-prone regions in Brazil as case studies and the role of large scale climate processes in generating extreme floods in such regions is explored by means of observed streamflow, reanalysis data and machine learning methods. The dynamics of the large scale atmospheric circulation in the days prior to the flood events are evaluated based on the vertically integrated moisture flux and its divergence field, which are interpreted in a low-dimensional space as obtained by machine learning techniques, particularly supervised kernel principal component analysis. In such reduced dimensional space, clusters are obtained in order to better understand the role of regional moisture recycling or teleconnected moisture in producing floods of a given magnitude. The convective available potential energy (CAPE) is also used as a measure of local convection activities. We investigate for individual sites the exceedance probability in which large scale atmospheric fluxes dominate the flood process. Finally, we analyze regional patterns of floods and how the scaling law of floods with drainage area responds to changes in the climate forcing mechanisms (e.g. local vs large scale).

Adding large EM stack support

KAUST Repository

Holst, Glendon

2016-12-01

Serial section electron microscopy (SSEM) image stacks generated using high throughput microscopy techniques are an integral tool for investigating brain connectivity and cell morphology. FIB or 3View scanning electron microscopes easily generate gigabytes of data. In order to produce analyzable 3D dataset from the imaged volumes, efficient and reliable image segmentation is crucial. Classical manual approaches to segmentation are time consuming and labour intensive. Semiautomatic seeded watershed segmentation algorithms, such as those implemented by ilastik image processing software, are a very powerful alternative, substantially speeding up segmentation times. We have used ilastik effectively for small EM stacks – on a laptop, no less; however, ilastik was unable to carve the large EM stacks we needed to segment because its memory requirements grew too large – even for the biggest workstations we had available. For this reason, we refactored the carving module of ilastik to scale it up to large EM stacks on large workstations, and tested its efficiency. We modified the carving module, building on existing blockwise processing functionality to process data in manageable chunks that can fit within RAM (main memory). We review this refactoring work, highlighting the software architecture, design choices, modifications, and issues encountered.

Extensive young silicic volcanism produces large deep submarine lava flows in the NE Lau Basin

Science.gov (United States)

Embley, Robert W.; Rubin, Kenneth H.

2018-04-01

New field observations reveal that extensive (up to 402 km2) aphyric, glassy dacite lavas were erupted at multiple sites in the recent past in the NE Lau basin, located about 200 km southwest of Samoa. This discovery of volumetrically significant and widespread submarine dacite lava flows extends the domain for siliceous effusive volcanism into the deep seafloor. Although several lava flow fields were discovered on the flank of a large silicic seamount, Niuatahi, two of the largest lava fields and several smaller ones ("northern lava flow fields") were found well north of the seamount. The most distal portion of the northernmost of these fields is 60 km north of the center of Niuatahi caldera. We estimate that lava flow lengths from probable eruptive vents to the distal ends of flows range from a few km to more than 10 km. Camera tows on the shallower, near-vent areas show complex lava morphology that includes anastomosing tube-like pillow flows and ropey surfaces, endogenous domes and/or ridges, some with "crease-like" extrusion ridges, and inflated lobes with extrusion structures. A 2 × 1.5 km, 30-m deep depression could be an eruption center for one of the lava flow fields. The Lau lava flow fields appear to have erupted at presumptive high effusion rates and possibly reduced viscosity induced by presumptive high magmatic water content and/or a high eruption temperature, consistent with both erupted composition ( 66% SiO2) and glassy low crystallinity groundmass textures. The large areal extent (236 km2) and relatively small range of compositional variation ( σ = 0.60 for wt% Si02%) within the northern lava flow fields imply the existence of large, eruptible batches of differentiated melt in the upper mantle or lower crust of the NE Lau basin. At this site, the volcanism could be controlled by deep crustal fractures caused by the long-term extension in this rear-arc region. Submarine dacite flows exhibiting similar morphology have been described in ancient

Antimicrobial properties of Pseudomonas strains producing the antibiotic mupirocin.

Science.gov (United States)

Matthijs, Sandra; Vander Wauven, Corinne; Cornu, Bertrand; Ye, Lumeng; Cornelis, Pierre; Thomas, Christopher M; Ongena, Marc

2014-10-01

Mupirocin is a polyketide antibiotic with broad antibacterial activity. It was isolated and characterized about 40 years ago from Pseudomonas fluorescens NCIMB 10586. To study the phylogenetic distribution of mupirocin producing strains in the genus Pseudomonas a large collection of Pseudomonas strains of worldwide origin, consisting of 117 Pseudomonas type strains and 461 strains isolated from different biological origins, was screened by PCR for the mmpD gene of the mupirocin gene cluster. Five mmpD(+) strains from different geographic and biological origin were identified. They all produced mupirocin and were strongly antagonistic against Staphylococcus aureus. Phylogenetic analysis showed that mupirocin production is limited to a single species. Inactivation of mupirocin production leads to complete loss of in vitro antagonism against S. aureus, except on certain iron-reduced media where the siderophore pyoverdine is responsible for the in vitro antagonism of a mupirocin-negative mutant. In addition to mupirocin some of the strains produced lipopeptides of the massetolide group. These lipopeptides do not play a role in the observed in vitro antagonism of the mupirocin producing strains against S. aureus. Copyright © 2014 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

Timeliness of Surveillance during Outbreak of Shiga Toxin–producing Escherichia coli Infection, Germany, 2011

OpenAIRE

Altmann, Mathias; Wadl, Maria; Altmann, Doris; Benzler, Justus; Eckmanns, Tim; Krause, Gérard; Spode, Anke; an der Heiden, Matthias

2011-01-01

In the context of a large outbreak of Shiga toxin–producing Escherichia coli O104:H4 in Germany, we quantified the timeliness of the German surveillance system for hemolytic uremic syndrome and Shiga toxin–producing E. coli notifiable diseases during 2003–2011. Although reporting occurred faster than required by law, potential for improvement exists at all levels of the information chain.

Comparative costs of hydrogen produced from photovoltaic electrolysis and from photoelectrochemical processes

International Nuclear Information System (INIS)

Block, D.L.

1998-01-01

The need for hydrogen produced from renewable energy sources is the key element to the world's large-scale usage of hydrogen and to the hydrogen economy envisioned by the World Hydrogen Energy Association. Renewables-produced hydrogen is also the most technically difficult problem to be solved. Hydrogen will never achieve large-scale usage until it can be competitively produced from renewable energy. One of the important questions that has to be addressed is: What are the economics of present and expected future technologies that will be used to produce hydrogen from renewables? The objective of this study is to give an answer to this question by determining the cost of hydrogen (in U.S.$/MBtu) from competing renewable production technologies. It should be noted that the costs and efficiencies assumed in this paper are assumptions of the author, and that the values are expected to be achieved after additional research on photoelectrochemical process technologies. The cost analysis performed is for three types of hydrogen (H 2 ) produced from five different types of renewable processes: photovoltaic (PV) electrolysis, three photoelectrochemical (PEC) processes and higher temperature electrolysis (HTE). The costs and efficiencies for PV, PEC and HTE processes are established for present day, and for expected costs and efficiencies 10 years into the future. A second objective of this analysis is to set base case costs of PV electrolysis. For any other renewable process, the costs for PV electrolysis, which is existing technology, sets the numbers which the other processes must better. (author)

The promise of the large collider

CERN Multimedia

2007-01-01

"In 2007, the most powerful particle accelerator ever built, CERN's new Large hadron Collider, will probe the secrets of matter in the energy states prevailing in the moments after the Big Bang. By colliding particles together when they are moving at close to the speed of ight, physicists hope to find out about matter in its earliest forms, using the energy produced by the collisions." (2 pages)

Talaromyces atroroseus, a new species efficiently producing industrially relevant red pigments.

Directory of Open Access Journals (Sweden)

Jens C Frisvad

Full Text Available Some species of Talaromyces secrete large amounts of red pigments. Literature has linked this character to species such as Talaromyces purpurogenus, T. albobiverticillius, T. marneffei, and T. minioluteus often under earlier Penicillium names. Isolates identified as T. purpurogenus have been reported to be interesting industrially and they can produce extracellular enzymes and red pigments, but they can also produce mycotoxins such as rubratoxin A and B and luteoskyrin. Production of mycotoxins limits the use of isolates of a particular species in biotechnology. Talaromyces atroroseus sp. nov., described in this study, produces the azaphilone biosynthetic families mitorubrins and Monascus pigments without any production of mycotoxins. Within the red pigment producing clade, T. atroroseus resolved in a distinct clade separate from all the other species in multigene phylogenies (ITS, β-tubulin and RPB1, which confirm its unique nature. Talaromyces atroroseus resembles T. purpurogenus and T. albobiverticillius in producing red diffusible pigments, but differs from the latter two species by the production of glauconic acid, purpuride and ZG-1494α and by the dull to dark green, thick walled ellipsoidal conidia produced. The type strain of Talaromyces atroroseus is CBS 133442.

Large Bandgap Semiconductors for Solar Water Splitting

DEFF Research Database (Denmark)

Malizia, Mauro

Photoelectrochemical water splitting represents an eco-friendly technology that could enable the production of hydrogen using water as reactant and solar energy as primary energy source. The exploitation of solar energy for the production of hydrogen would help modern society to reduce the reliance...... on fossil fuels as primary feedstock for hydrogen production and diminish the emission of greenhouse gases in the atmosphere, weakening the global warming phenomenon.The dissertation reports the development of GaP (gallium phosphide) photocathodes as a large bandgap semiconductor for photoelectrochemical...... water splitting devices having tandem design. The increase of the photovoltage produced by GaP under illumination was the main goal of this work. GaP has a bandgap of 2.25 eV and could in theory produce a photovoltage of approximately 1.7 V. Instead, the photovoltage produced by the semiconductor...

Using thermoforming capacity of metallic glasses to produce multimaterials

International Nuclear Information System (INIS)

Ragani, J.; Volland, A.; Valque, S.; Liu, Y.; Gravier, S.; Blandin, J.J.; Suery, M.

2010-01-01

In addition to casting, thermoforming is a particularly interesting way to produce components in bulk metallic glasses since large strains can be achieved when the BMGs are deformed in their supercooled liquid region. The experimental window (temperature, time) in which high temperature forming can be carried out is directly related to the crystallization resistance of the glass. Such forming windows have been identified for zirconium based bulk metallic glasses thanks to thermal analysis and compression tests in the supercooled liquid region. Based on this identification, the thermoforming capacity of the studied glasses was used to produce multimaterials associating metallic glasses with conventional metallic alloys. Two processes have been preferentially investigated (co-extrusion and co-pressing) and the interface quality of the elaborated multi materials was studied.

Stable, fertile, high polyhydroxyalkanoate producing plants and methods of producing them

Energy Technology Data Exchange (ETDEWEB)

Bohmert-Tatarev, Karen; McAvoy, Susan; Peoples, Oliver P.; Snell, Kristi D.

2015-08-04

Transgenic plants that produce high levels of polyhydroxybutyrate and methods of producing them are provided. In a preferred embodiment the transgenic plants are produced using plastid transformation technologies and utilize genes which are codon optimized. Stably transformed plants able to produce greater than 10% dwt PHS in tissues are also provided.

Characterization of Briquette Produced from Tannery Solid Waste

Directory of Open Access Journals (Sweden)

Olatunde Ajani Oyelaran

2017-06-01

Full Text Available Skin processing produces large volumes of wastes, much of which are not utilized but disposed in the landfill. This study explored the possibility of producing briquettes from tannery waste that could be used for heating purposes for cottage factories and domestic cooking. Wastes studied are buffing dust, chrome shavings, fleshing, and hair. The briquette properties tested were moisture content, volatile matter, ash content, fixed carbon content, calorific value, compressive strength, density and durability. The moisture content of the raw materials ranged between 2.04 and 8.37% while the moisture content of the produced briquettes after 19 days of drying ranges between 1.17 and 4.13%. The volatile matter also decreases while the ash content increases after briquetting. The fixed carbon content ranges 73.79 and 93.23%. The heating values of the briquettes also showed a great increased after briquetting of between 19.82 and 21.86 MJ/kg. The compressive strength ranges between 0.17 and 0.21 kN/cm2, the durability ranges between 97.83 and 99.54%. The maximum densities of the briquettes also meet the required specifications of minimum value of 600 kg/m3. The briquettes produced also possess good qualities that make tannery solid waste a materials for production of briquettes for heating and in cottage industries

Timeliness of Surveillance during Outbreak of Shiga Toxin–producing Escherichia coli Infection, Germany, 2011

Science.gov (United States)

Wadl, Maria; Altmann, Doris; Benzler, Justus; Eckmanns, Tim; Krause, Gérard; Spode, Anke; an der Heiden, Matthias

2011-01-01

In the context of a large outbreak of Shiga toxin–producing Escherichia coli O104:H4 in Germany, we quantified the timeliness of the German surveillance system for hemolytic uremic syndrome and Shiga toxin–producing E. coli notifiable diseases during 2003–2011. Although reporting occurred faster than required by law, potential for improvement exists at all levels of the information chain. PMID:22000368

Characteristics of VLF/LF Sferics from Elve-producing Lightning Discharges

Science.gov (United States)

Blaes, P.; Zoghzoghy, F. G.; Marshall, R. A.

2013-12-01

Lightning return strokes radiate an electromagnetic pulse (EMP) which interacts with the D-region ionosphere; the largest EMPs produce new ionization, heating, and optical emissions known as elves. Elves are at least six times more common than sprites and other transient luminous events. Though the probability that a lightning return stroke will produce an elve is correlated with the return stroke peak current, many large peak current strokes do not produce visible elves. Apart from the lightning peak current, elve production may depend on the return stroke speed, lightning altitude, and ionospheric conditions. In this work we investigate the detailed structure of lightning that gives rise to elves by analyzing the characteristics of VLF/LF lightning sferics in conjunction with optical elve observations. Lightning sferics were observed using an array of six VLF/LF receivers (1 MHz sample-rate) in Oklahoma, and elves were observed using two high-speed photometers pointed over the Oklahoma region: one located at Langmuir Laboratory, NM and the other at McDonald Observatory, TX. Hundreds of elves with coincident LF sferics were observed during the summer months of 2013. We present data comparing the characteristics of elve-producing and non-elve producing lightning as measured by LF sferics. In addition, we compare these sferic and elve observations with FDTD simulations to determine key properties of elve-producing lightning.

Method of producing excited states of atomic nuclei

International Nuclear Information System (INIS)

Morita, M.; Morita, R.

1976-01-01

A method is claimed of producing excited states of atomic nuclei which comprises bombarding atoms with x rays or electrons, characterized in that (1) in the atoms selected to be produced in the excited state of their nuclei, (a) the difference between the nuclear excitation energy and the difference between the binding energies of adequately selected two electron orbits is small enough to introduce the nuclear excitation by electron transition, and (b) the system of the nucleus and the electrons in the case of ionizing an orbital electron in said atoms should satisfy the spin and parity conservation laws; and (2) the energy of the bombarding x rays or electrons should be larger than the binding energy of one of the said two electron orbits which is located at shorter distance from the atomic nucleus. According to the present invention, atomic nuclei can be excited in a relatively simple manner without requiring the use of large scale apparatus, equipment and production facilities, e.g., factories. It is also possible to produce radioactive substances or separate a particular isotope with an extremely high purity from a mixture of isotopes by utilizing nuclear excitation

Nuclear-pumped lasers for large-scale applications

International Nuclear Information System (INIS)

Anderson, R.E.; Leonard, E.M.; Shea, R.F.; Berggren, R.R.

1989-05-01

Efficient initiation of large-volume chemical lasers may be achieved by neutron induced reactions which produce charged particles in the final state. When a burst mode nuclear reactor is used as the neutron source, both a sufficiently intense neutron flux and a sufficiently short initiation pulse may be possible. Proof-of-principle experiments are planned to demonstrate lasing in a direct nuclear-pumped large-volume system; to study the effects of various neutron absorbing materials on laser performance; to study the effects of long initiation pulse lengths; to demonstrate the performance of large-scale optics and the beam quality that may be obtained; and to assess the performance of alternative designs of burst systems that increase the neutron output and burst repetition rate. 21 refs., 8 figs., 5 tabs

Large-scale patterns in Rayleigh-Benard convection

International Nuclear Information System (INIS)

Hardenberg, J. von; Parodi, A.; Passoni, G.; Provenzale, A.; Spiegel, E.A.

2008-01-01

Rayleigh-Benard convection at large Rayleigh number is characterized by the presence of intense, vertically moving plumes. Both laboratory and numerical experiments reveal that the rising and descending plumes aggregate into separate clusters so as to produce large-scale updrafts and downdrafts. The horizontal scales of the aggregates reported so far have been comparable to the horizontal extent of the containers, but it has not been clear whether that represents a limitation imposed by domain size. In this work, we present numerical simulations of convection at sufficiently large aspect ratio to ascertain whether there is an intrinsic saturation scale for the clustering process when that ratio is large enough. From a series of simulations of Rayleigh-Benard convection with Rayleigh numbers between 10 5 and 10 8 and with aspect ratios up to 12π, we conclude that the clustering process has a finite horizontal saturation scale with at most a weak dependence on Rayleigh number in the range studied

Meta-analysis of proportion estimates of Extended-Spectrum-Beta-Lactamase-producing Enterobacteriaceae in East Africa hospitals

DEFF Research Database (Denmark)

Sonda, Tolbert; Kumburu, Happiness; van Zwetselaar, Marco

2016-01-01

Background: A high proportion of Extended-Spectrum-Beta-Lactamase (ESBL) producing Enterobacteriaceae is causing common infections in all regions of the world. The burden of antibiotic resistance due to ESBL in East Africa is large but information is scarce and thus it is unclear how big the prob......Background: A high proportion of Extended-Spectrum-Beta-Lactamase (ESBL) producing Enterobacteriaceae is causing common infections in all regions of the world. The burden of antibiotic resistance due to ESBL in East Africa is large but information is scarce and thus it is unclear how big...... the problem really is. To gain insight into the magnitude and molecular epidemiology of ESBL-producing Enterobacteriaceae in East Africa a literature search was performed in PubMed on 31 July 2015 to retrieve articles with relevant information on ESBL. Methods and results: Meta-analysis was performed...... to determine overall proportion estimate of ESBL-producing Enterobacteriaceae. A total of 4076 bacterial isolates were included in the analysis. The overall pooled proportion of ESBL-producing Enterobacteriaceae among included surveys done in East African hospitals was found to be 0. 42 (95 % CI: 0...

Large amounts of antiproton production by heavy ion collision

International Nuclear Information System (INIS)

Takahashi, Hiroshi; Powell, J.

1987-01-01

To produce large amounts of antiprotons, on the order of several grams/year, use of machines to produce nuclear collisions are studied. These can be of either proton-proton, proton-nucleus and nucleus-nucleus in nature. To achieve high luminosity colliding beams, on the order of 10 41 m/cm 2 , a self-colliding machine is required, rather than a conventional circular colliding type. The self-colliding machine can produce additional antiprotons through successive collisions of secondary particles, such as spectator nucleons. A key problem is how to collect the produced antiprotons without capture by beam nuclei in the collision zone. Production costs for anti-matter are projected for various energy source options and technology levels. Dedicated facilities using heavy ion collisions could produce antiproton at substantially less than 1 million $/milligram. With co-production of other valuable products, e.g., nuclear fuel for power reactors, antiproton costs could be reduced to even lower values

Large amounts of antiproton production by heavy ion collision

Energy Technology Data Exchange (ETDEWEB)

Takahashi, Hiroshi; Powell, J.

1987-01-01

To produce large amounts of antiprotons, on the order of several grams/year, use of machines to produce nuclear collisions are studied. These can be of either proton-proton, proton-nucleus and nucleus-nucleus in nature. To achieve high luminosity colliding beams, on the order of 10/sup 41/ m/cm/sup 2/, a self-colliding machine is required, rather than a conventional circular colliding type. The self-colliding machine can produce additional antiprotons through successive collisions of secondary particles, such as spectator nucleons. A key problem is how to collect the produced antiprotons without capture by beam nuclei in the collision zone. Production costs for anti-matter are projected for various energy source options and technology levels. Dedicated facilities using heavy ion collisions could produce antiproton at substantially less than 1 million $/milligram. With co-production of other valuable products, e.g., nuclear fuel for power reactors, antiproton costs could be reduced to even lower values.

Operational Aspects of Fiscal Policy in Oil-Producing Countries

OpenAIRE

Steven A Barnett; Rolando Ossowski

2002-01-01

Oil-producing countries face challenges arising from the fact that oil revenue is exhaustible, volatile, and uncertain, and largely originates from abroad. Reflecting these challenges, the paper proposes some important general principles for the formulation and assessment of fiscal policy in these countries. The main findings can be summarized in some key guidelines: the non-oil balance should feature prominently in the formulation of fiscal policy; it should generally be adjusted gradually; ...

Neutrino fluxes produced by high energy solar flare particles

International Nuclear Information System (INIS)

Kolomeets, E.V.; Shmonin, V.L.

1975-01-01

In this work the calculated differential energy spectra of neutrinos poduced by high energy protons accelerated during 'small' solar flares are presented. The muon flux produced by neutrino interactions with the matter at large depths under the ground is calculated. The obtained flux of muons for the total number of solar flare accelerated protons of 10 28 - 10 32 is within 10 9 - 10 13 particles/cm 2 X s x ster. (orig.) [de

Effect of riboflavin-producing bacteria against chemically induced colitis in mice.

Science.gov (United States)

Levit, R; Savoy de Giori, G; de Moreno de LeBlanc, A; LeBlanc, J G

2018-01-01

To assess the anti-inflammatory effect associated with individual probiotic suspensions of riboflavin-producing lactic acid bacteria (LAB) in a colitis murine model. Mice intrarectally inoculated with trinitrobenzene sulfonic acid (TNBS) were orally administered with individual suspensions of riboflavin-producing strains: Lactobacillus (Lact.) plantarum CRL2130, Lact. paracasei CRL76, Lact. bulgaricus CRL871 and Streptococcus thermophilus CRL803; and a nonriboflavin-producing strain or commercial riboflavin. The extent of colonic damage and inflammation and microbial translocation to liver were evaluated. iNOs enzyme was analysed in the intestinal tissues and cytokine concentrations in the intestinal fluids. Animals given either one of the four riboflavin-producing strains showed lower macroscopic and histologic damage scores, lower microbial translocation to liver, significant decreases of iNOs+ cells in their large intestines and decreased proinflammatory cytokines, compared with mice without treatment. The administration of pure riboflavin showed similar benefits. Lact. paracasei CRL76 accompanied its anti-inflammatory effect with increased IL-10 levels demonstrating other beneficial properties in addition to the vitamin production. Administration of riboflavin-producing strains prevented the intestinal damage induced by TNBS in mice. Riboflavin-producing phenotype in LAB represents a potent tool to select them for preventing/treating IBD. © 2017 The Society for Applied Microbiology.

Double inflation: A possible resolution of the large-scale structure problem

International Nuclear Information System (INIS)

Turner, M.S.; Villumsen, J.V.; Vittorio, N.; Silk, J.; Juszkiewicz, R.

1986-11-01

A model is presented for the large-scale structure of the universe in which two successive inflationary phases resulted in large small-scale and small large-scale density fluctuations. This bimodal density fluctuation spectrum in an Ω = 1 universe dominated by hot dark matter leads to large-scale structure of the galaxy distribution that is consistent with recent observational results. In particular, large, nearly empty voids and significant large-scale peculiar velocity fields are produced over scales of ∼100 Mpc, while the small-scale structure over ≤ 10 Mpc resembles that in a low density universe, as observed. Detailed analytical calculations and numerical simulations are given of the spatial and velocity correlations. 38 refs., 6 figs

Vortex-ring-induced large bubble entrainment during drop impact

KAUST Repository

Thoraval, Marie-Jean; Li, Yangfan; Thoroddsen, Sigurdur T

2016-01-01

, produced in the neck between the drop and the pool, controls the crater deformations and pinchoff. However, it is not the strongest vortex rings that are responsible for the large bubbles, as they interact too strongly with the pool surface and self

No Large Scale Curvature Perturbations during Waterfall of Hybrid Inflation

OpenAIRE

Abolhasani, Ali Akbar; Firouzjahi, Hassan

2010-01-01

In this paper the possibility of generating large scale curvature perturbations induced from the entropic perturbations during the waterfall phase transition of standard hybrid inflation model is studied. We show that whether or not appreciable amounts of large scale curvature perturbations are produced during the waterfall phase transition depend crucially on the competition between the classical and the quantum mechanical back-reactions to terminate inflation. If one considers only the clas...

Treatment of Oil & Gas Produced Water.

Energy Technology Data Exchange (ETDEWEB)

Dwyer, Brian P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2016-02-01

Production of oil and gas reserves in the New Mexico Four Corners Region results in large volumes of "produced water". The common method for handling the produced water from well production is re-injection in regulatory permitted salt water disposal wells. This is expensive (%7E $5/bbl.) and does not recycle water, an ever increasingly valuable commodity. Previously, Sandia National Laboratories and several NM small business tested pressure driven membrane-filtration techniques to remove the high TDS (total dissolved solids) from a Four Corners Coal Bed Methane produced water. Treatment effectiveness was less than optimal due to problems with pre-treatment. Inadequate pre-treatment allowed hydrocarbons, wax and biological growth to foul the membranes. Recently, an innovative pre-treatment scheme using ozone and hydrogen peroxide was pilot tested. Results showed complete removal of hydrocarbons and the majority of organic constituents from a gas well production water. ACKNOWLEDGEMENTS This report was made possible through funding from the New Mexico Small Business Administration (NMSBA) Program at Sandia National Laboratories. Special thanks to Juan Martinez and Genaro Montoya for guidance and support from project inception to completion. Also, special thanks to Frank McDonald, the small businesses team POC, for laying the ground work for the entire project; Teresa McCown, the gas well owner and very knowledgeable- fantastic site host; Lea and Tim Phillips for their tremendous knowledge and passion in the oil & gas industry.; and Frank Miller and Steve Addleman for providing a pilot scale version of their proprietary process to facilitate the pilot testing.

Dichlorinated and Brominated Rugulovasines, Ergot Alkaloids Produced by Talaromyces wortmannii

DEFF Research Database (Denmark)

Soman De Medeiros, Lívia; da Silva, José Vinícius; Abreu, Lucas Magalhães

2015-01-01

UHPLC-DAD-HRMS based dereplication guided the detection of new halogenated alkaloids co-produced by Talaromyces wortmannii. From the fungal growth in large scale, the epimers 2,8-dichlororugulovasines A and B were purified and further identified by means of a HPLC-SPE/NMR hyphenated system...

Bio-based production of fuels and industrial chemicals by repurposing antibiotic-producing type I modular polyketide synthases: opportunities and challenges.

Science.gov (United States)

Yuzawa, Satoshi; Keasling, Jay D; Katz, Leonard

2017-04-01

Complex polyketides comprise a large number of natural products that have broad application in medicine and agriculture. They are produced in bacteria and fungi from large enzyme complexes named type I modular polyketide synthases (PKSs) that are composed of multifunctional polypeptides containing discrete enzymatic domains organized into modules. The modular nature of PKSs has enabled a multitude of efforts to engineer the PKS genes to produce novel polyketides of predicted structure. We have repurposed PKSs to produce a number of short-chain mono- and di-carboxylic acids and ketones that could have applications as fuels or industrial chemicals.

Bio-based production of fuels and industrial chemicals by repurposing antibiotic-producing type I modular polyketide synthases: opportunities and challenges

Energy Technology Data Exchange (ETDEWEB)

Yuzawa, Satoshi [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Biological Systems and Engineering Division; Keasling, Jay D. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Biological Systems and Engineering Division; Univ. of California, Berkeley, CA (United States). QB3 Inst.; Joint BioEnergy Inst. (JBEI), Emeryville, CA (United States); Univ. of California, Berkeley, CA (United States). Dept. of Bioengineering; Univ. of California, Berkeley, CA (United States). Dept. of Chemical and Biomolecular Engineering; Technical Univ. of Denmark, Horsholm (Denmark). Novo Nordisk Foundation Center for Biosustainability; Katz, Leonard [Univ. of California, Berkeley, CA (United States). QB3 Inst.

2016-11-16

Complex polyketides comprise a large number of natural products that have broad application in medicine and agriculture. They are produced in bacteria and fungi from large enzyme complexes named type I modular polyketide synthases (PKSs) that are composed of multifunctional polypeptides containing discrete enzymatic domains organized into modules. The modular nature of PKSs has enabled a multitude of efforts to engineer the PKS genes to produce novel polyketides of predicted structure. Finally, we have repurposed PKSs to produce a number of short-chain mono- and di-carboxylic acids and ketones that could have applications as fuels or industrial chemicals.

Convective mechanism for inhibition of heat conduction in laser produced plasmas

International Nuclear Information System (INIS)

Lee, P.H.Y.; Willi, O.; Trainor, R.J.

1984-01-01

In laser-produced plasmas, the laser energy is absorbed only below and up to the critical density. For laser fusion applications, this energy must be transported beyond the corona via electron thermal conduction towards colder, higher density regions of the target to heat up material and cause ablation, which in turn generates an inward pressure to compress the fusion fuel. If the heat conduction is inhibited, the consequences will be a weaker ablation and therefore a weaker implosion. For many years now, the inhibition of heat conduction, i.e., the reduction of heat conduction relative to classical conduction, in laser-produced plasmas at relevant irradiances has been apparent from the large body of experimental evidence. Many mechanisms, such as dc magnetic fields, ion acoustic turbulence, and Weibel instabilities, have been proposed to be the cause of inhibition of heat conduction. Even improved calculations of the classical heat flux have been carried out to solve this problem. Nevertheless, no single one of the above mentioned mechanisms can explain the large inhibition observed in the experiments

Local features with large spiky non-Gaussianities during inflation

International Nuclear Information System (INIS)

Abolhasani, Ali Akbar; Firouzjahi, Hassan; Khosravi, Shahram; Sasaki, Misao

2012-01-01

We provide a dynamical mechanism to generate localized features during inflation. The local feature is due to a sharp waterfall phase transition which is coupled to the inflaton field. The key effect is the contributions of waterfall quantum fluctuations which induce a sharp peak on the curvature perturbation which can be as large as the background curvature perturbation from inflaton field. Due to non-Gaussian nature of waterfall quantum fluctuations a large spike non-Gaussianity is produced which is narrowly peaked at modes which leave the Hubble radius at the time of phase transition. The large localized peaks in power spectrum and bispectrum can have interesting consequences on CMB anisotropies

Emerging Perspectives on the Natural Microbiome of Fresh Produce Vegetables

Directory of Open Access Journals (Sweden)

Colin R. Jackson

2015-04-01

Full Text Available Plants harbor a diverse microbiome existing as bacterial populations on the leaf surface (the phyllosphere and within plant tissues (endophytes. The composition of this microbiome has been largely unexplored in fresh produce vegetables, where studies have tended to focus on pathogen detection and survival. However, the application of next-generation 16S rRNA gene sequencing approaches is beginning to reveal the diversity of this produce-associated bacterial community. In this article we review what is known about the composition of the microbiome of fresh produce vegetables, placing it in the context of general phyllosphere research. We also demonstrate how next-generation sequencing can be used to assess the bacterial assemblages present on fresh produce, using fresh herbs as an example. That data shows how the use of such culture-independent approaches can detect groups of taxa (anaerobes, psychrophiles that may be missed by traditional culture-based techniques. Other issues discussed include questions as to whether to determine the microbiome during plant growth or at point of purchase or consumption, and the potential role of the natural bacterial community in mitigating pathogen survival.

CCT`s in a deregulated environment: A producer`s perspective

Energy Technology Data Exchange (ETDEWEB)

Edmonds, R.F. Jr.; Fayssoux, J.O. [Duke Power Co., Charlotte, NC (United States)

1997-12-31

The US electric industry will be deregulated (or substantially re-regulated) within 5 years. Several states, including California, Rhode Island, and New Hampshire, already have passed legislation to introduce competition into the electric markets before the year 2000. As this trend sweeps across the country, the resulting competitive market for generation will reward the lowest cost producers and force high cost producers out of the market. As a result, at least in the short run, it may be very difficult for new power plants employing Clean Coal Technologies (CCTs) to compete. This paper discusses a producer`s perspective of the new competitive market, and suggests several short and long term strategies and niches for CCTs.

THE 'TWIN-CME' SCENARIO AND LARGE SOLAR ENERGETIC PARTICLE EVENTS IN SOLAR CYCLE 23

Energy Technology Data Exchange (ETDEWEB)

Ding, Liuguan; Jiang, Yong [College of Math and Physics, Nanjing University of Information Science and Technology, Nanjing, Jiangsu 210044 (China); Zhao, Lulu; Li, Gang, E-mail: gang.li@uah.edu [Department of Physics and CSPAR, University of Alabama in Huntsville, AL 35899 (United States)

2013-01-20

Energetic particles in large solar energetic particle (SEP) events are a major concern for space weather. Recently, Li et al. proposed a 'twin-CME' scenario for ground-level events. Here we extend that study to large SEP events in solar cycle 23. Depending on whether preceding coronal mass ejections (CMEs) within 9 hr exist and whether ions >10 MeV nucleon{sup -1} exceed 10 pfu, we categorize fast CMEs with speed >900 km s{sup -1} and width >60 Degree-Sign from the western hemisphere source regions into four groups: groups I and II are 'twin' and single CMEs that lead to large SEPs; groups III and IV are 'twin' and single CMEs that do not lead to large SEPs. The major findings of this paper are: first, large SEP events tend to be 'twin-CME' events. Of 59 western large SEP events in solar cycle 23, 43 are 'twin-CME' (group I) events and 16 are single-CME (group II) events. Second, not all 'twin CMEs' produced large SEPs: 28 twin CMEs did not produce large SEPs (group III events). Some of them produced excesses of particles up to a few MeV nucleon{sup -1}. Third, there were 39 single fast CMEs that did not produce SEPs (group IV events). Some of these also showed an excess of particles up to a few MeV nucleon{sup -1}. For all four groups of events, we perform statistical analyses on properties such as the angular width, the speed, the existence of accompanying metric type II radio bursts, and the associated flare class for the main CMEs and the preceding CMEs.

Biofilm-forming capacity in biogenic amine-producing bacteria isolated from dairy products.

Directory of Open Access Journals (Sweden)

Maria eDiaz

2016-05-01

Full Text Available Biofilms on the surface of food industry equipment are reservoirs of potentially food-contaminating bacteria - both spoilage and pathogenic. However, the capacity of biogenic amine (BA-producers to form biofilms has remained largely unexamined. BAs are low molecular weight, biologically active compounds that in food can reach concentrations high enough to be a toxicological hazard. Fermented foods, especially some types of cheese, accumulate the highest BA concentrations of all. The present work examines the biofilm-forming capacity of 56 BA-producing strains belonging to three genera and 10 species (12 Enterococcus faecalis, 6 Enterococcus faecium, 6 Enterococcus durans, 1 Enterococcus hirae, 12 Lactococcus lactis, 7 Lactobacillus vaginalis, 2 Lactobacillus curvatus, 2 Lactobacillus brevis, 1 Lactobacillus reuteri and 7 Lactobacillus parabuchneri, all isolated from dairy products. Strains of all the tested species - except for L. vaginalis - were able to produce biofilms on polystyrene and adhered to stainless steel. However, the biomass produced in biofilms was strain-dependent. These results suggest that biofilms may provide a route via which fermented foods can become contaminated by BA-producing microorganisms.

BigSUR: large-scale structured urban reconstruction

KAUST Repository

Kelly, Tom

2017-11-22

The creation of high-quality semantically parsed 3D models for dense metropolitan areas is a fundamental urban modeling problem. Although recent advances in acquisition techniques and processing algorithms have resulted in large-scale imagery or 3D polygonal reconstructions, such data-sources are typically noisy, and incomplete, with no semantic structure. In this paper, we present an automatic data fusion technique that produces high-quality structured models of city blocks. From coarse polygonal meshes, street-level imagery, and GIS footprints, we formulate a binary integer program that globally balances sources of error to produce semantically parsed mass models with associated facade elements. We demonstrate our system on four city regions of varying complexity; our examples typically contain densely built urban blocks spanning hundreds of buildings. In our largest example, we produce a structured model of 37 city blocks spanning a total of 1,011 buildings at a scale and quality previously impossible to achieve automatically.

BigSUR: large-scale structured urban reconstruction

KAUST Repository

Kelly, Tom; Femiani, John; Wonka, Peter; Mitra, Niloy J.

2017-01-01

The creation of high-quality semantically parsed 3D models for dense metropolitan areas is a fundamental urban modeling problem. Although recent advances in acquisition techniques and processing algorithms have resulted in large-scale imagery or 3D polygonal reconstructions, such data-sources are typically noisy, and incomplete, with no semantic structure. In this paper, we present an automatic data fusion technique that produces high-quality structured models of city blocks. From coarse polygonal meshes, street-level imagery, and GIS footprints, we formulate a binary integer program that globally balances sources of error to produce semantically parsed mass models with associated facade elements. We demonstrate our system on four city regions of varying complexity; our examples typically contain densely built urban blocks spanning hundreds of buildings. In our largest example, we produce a structured model of 37 city blocks spanning a total of 1,011 buildings at a scale and quality previously impossible to achieve automatically.

Diffuse ions produced by electromagnetic ion beam instabilities

International Nuclear Information System (INIS)

Winske, D.; Leroy, M.M.

1984-01-01

The evolution of the electromagnetic ions beam instability driven by the reflected ion component backstreaming away from the earth's how shock into the foreshock region is studied by means computer simulation. The linear the quasi-linear states of the instability are found to be in good agreement with known results for the resonant model propagating parallel to the beam along the magnetic field and with theory developed in this paper for the nonresonant mode, which propagates antiparallel to the beam direction. The quasi-linear stage, which produces large amplitude 8Bapprox.B, sinusoidal transverse waves and ''intermediate'' ion distribution, is terminated by a nonlinear phase in which strongly nonlinear, compressive waves and ''diffuse'' ion distributions are produced. Additional processes by which the diffuse ions are accelerated to observed high energies are not addressed. The results are discussed in terms of the ion distributions and hydromagnetic waves observed in the foreshock of the earth's bow shock and of interplanetary shocks

Phylogenetic Analysis of the Synnema-Producing Genus Synnemapestaloides

Directory of Open Access Journals (Sweden)

Kyoko Watanabe

2016-11-01

Full Text Available Synnemapestaloides rhododendri, the type species of the genus Synnemapestaloides, is a pathogen of Rhododendron brachycarpum. This fungus produces six-celled conidia with appendages at both end cells, and are generated by annellidic conidiogenous cells on the synnema. These conidial structures are similar to those of the genus Pestalotia. The monotypic genus Synnemapestaloides is currently classified in the family Amphisphaeriaceae solely based on conidial morphology. Here we demonstrate that Synnemapestaloides represents a distinct genus in the family Sporocadaceae (Amphisphaeriales based on differences in the nucleotide sequences of the partial large subunit rDNA gene, the rDNA internal transcribed spacer, and the partial β-tubulin. The genus most closely related to Synnemapestaloides is Seimatosporium and the species most similar to Synnemapestaloides rhododendri is Seim. foliicola which produces short synnema-like conidiomata (sporodochia. These results demonstrate that Seim. foliicola should be transferred to Synnemapestaloides, and also demonstrate that Sporocadaceae can have synnematal in addition to pycnidial and acervular conidiomata.

Producing Polymer Fibers by Electrospinning in Supercritical Fluids

Directory of Open Access Journals (Sweden)

Lu Li

2013-01-01

Full Text Available Nanofibers have a wide range of applications, including filtration and biomedical engineering. Porous or hollow fibers with large surface-to-volume ratios are more popular in some fields than the common nanofibers. Porous nanofibers can be obtained through electrospinning with highly volatile solvents or through special treatment following electrospinning. A new process where electrospinning is conducted in supercritical or near-critical CO2 to produce porous or hollow nanofibers has been summarized. In addition, a process entailing compressed N2-assisted electrospinning was attempted to produce PVP nanofibers in this work, but it was proved to be unsuccessful. Since the fiber morphologies are dependent on the phase behavior of organic solvents in supercritical fluids, ASPEN PLUS 2006 was used to simulate the phase equilibrium of the solvent-supercritical fluid system to explain why porous or hollow fibers can be obtained in compressed CO2, but not in compressed N2.

Large Aspect Ratio Tokamak Study

International Nuclear Information System (INIS)

Reid, R.L.; Holmes, J.A.; Houlberg, W.A.; Peng, Y.K.M.; Strickler, D.J.; Brown, T.G.; Wiseman, G.W.

1980-06-01

The Large Aspect Ratio Tokamak Study (LARTS) at Oak Ridge National Laboratory (ORNL) investigated the potential for producing a viable longburn tokamak reactor by enhancing the volt-second capability of the ohmic heating transformer through the use of high aspect ratio designs. The plasma physics, engineering, and economic implications of high aspect ratio tokamaks were assessed in the context of extended burn operation. Using a one-dimensional transport code plasma startup and burn parameters were addressed. The pulsed electrical power requirements for the poloidal field system, which have a major impact on reactor economics, were minimized by optimizing the startup and shutdown portions of the tokamak cycle. A representative large aspect ratio tokamak with an aspect ratio of 8 was found to achieve a burn time of 3.5 h at capital cost only approx. 25% greater than that of a moderate aspect ratio design tokamak

Integration of large amounts of wind power. Markets for trading imbalances

Energy Technology Data Exchange (ETDEWEB)

Neimane, Viktoria; Axelsson, Urban [Vattenfall Research and Development AB, Stockholm (Sweden); Gustafsson, Johan; Gustafsson, Kristian [Vattenfall Nordic Generation Management, Stockholm (Sweden); Murray, Robin [Vattenfall Vindkraft AB, Stockholm (Sweden)

2008-07-01

The well-known concerns about wind power are related to its intermittent nature and difficulty to make exact forecasts. The expected increase in balancing and reserve requirements due to wind power has been investigated in several studies. This paper takes the next step in studying integration of large amounts of wind power in Sweden. Several wind power producers' and corresponding balance providers' perspective is taken and their imbalance costs modeled. Larger producers having wind power spread over larger geographical areas will have lower relative costs than producers having their units concentrated within limited geographical area. Possibilities of the wind power producers to reduce the imbalance costs by acting on after sales market are exposed and compared. (orig.)

Astrophysics of magnetically collimated jets generated from laser-produced plasmas.

Science.gov (United States)

Ciardi, A; Vinci, T; Fuchs, J; Albertazzi, B; Riconda, C; Pépin, H; Portugall, O

2013-01-11

The generation of astrophysically relevant jets, from magnetically collimated, laser-produced plasmas, is investigated through three-dimensional, magnetohydrodynamic simulations. We show that for laser intensities I∼10(12)-10(14) W cm(-2), a magnetic field in excess of ∼0.1  MG, can collimate the plasma plume into a prolate cavity bounded by a shock envelope with a standing conical shock at its tip, which recollimates the flow into a supermagnetosonic jet beam. This mechanism is equivalent to astrophysical models of hydrodynamic inertial collimation, where an isotropic wind is focused into a jet by a confining circumstellar toruslike envelope. The results suggest an alternative mechanism for a large-scale magnetic field to produce jets from wide-angle winds.

Generation of low-Btu fuel gas from agricultural residues experiments with a laboratory scale gas producer

Energy Technology Data Exchange (ETDEWEB)

Williams, R O

1977-01-01

Two successive laboratory-scale, downdraft gas producers were fabricated and tested. Agricultural and food processing residues including walnut shells, corn cobs, tree prunings, and cotton gin waste, were converted to a low Btu producer gas. The performance of 2 spark ignition engines, when running on producer gas, was highly satisfactory. The ability of the producer to maintain a continuous supply of good quality gas was determined largely by firebox configuration. Fuel handling and fuel flow control problems tended to be specific to individual types of residues. During each test run, air input, firebox temperature, fuel consumption rate, and pressure differential across the producer were monitored. An overall conversion efficiency of 65% was achieved.

Algae-Produced Pfs25 Elicits Antibodies That Inhibit Malaria Transmission

Science.gov (United States)

Gregory, James A.; Li, Fengwu; Tomosada, Lauren M.; Cox, Chesa J.; Topol, Aaron B.; Vinetz, Joseph M.; Mayfield, Stephen

2012-01-01

Subunit vaccines are significantly more expensive to produce than traditional vaccines because they are based primarily on recombinant proteins that must be purified from the expression system. Despite the increased cost, subunit vaccines are being developed because they are safe, effective, and can elicit antibodies that confer protection against diseases that are not currently vaccine-preventable. Algae are an attractive platform for producing subunit vaccines because they are relatively inexpensive to grow, genetically tractable, easily scaled to large volumes, have a short generation time, and are devoid of inflammatory, viral, or prion contaminants often present in other systems. We tested whether algal chloroplasts can produce malaria transmission blocking vaccine candidates, Plasmodium falciparum surface protein 25 (Pfs25) and 28 (Pfs28). Antibodies that recognize Pfs25 and Pfs28 disrupt the sexual development of parasites within the mosquito midgut, thus preventing transmission of malaria from one human host to the next. These proteins have been difficult to produce in traditional recombinant systems because they contain tandem repeats of structurally complex epidermal growth factor-like domains, which cannot be produced in bacterial systems, and because they are not glycosylated, so they must be modified for production in eukaryotic systems. Production in algal chloroplasts avoids these issues because chloroplasts can fold complex eukaryotic proteins and do not glycosylate proteins. Here we demonstrate that algae are the first recombinant system to successfully produce an unmodified and aglycosylated version of Pfs25 or Pfs28. These antigens are structurally similar to the native proteins and antibodies raised to these recombinant proteins recognize Pfs25 and Pfs28 from P. falciparum. Furthermore, antibodies to algae-produced Pfs25 bind the surface of in-vitro cultured P. falciparum sexual stage parasites and exhibit transmission blocking activity. Thus

Intermittency in multiparticle production produced by low momentum transfer at high energies

International Nuclear Information System (INIS)

Jang, Han Il; Jeong, Eun Mi; Kim, Jae Yool; Kim, Jae Young; Kim, Min Kyoung; Kim, Sin Joung; Kim, Tae Ick; Kim, Yeon Kyoung; Lee, Jin Ho; Lim, In Taek; Pac, Myoung Youl; Kim, Chong Oh; Bahk, Sang Yull

1998-01-01

We show the intermittent behavior of the distribution of the pseudo-rapidities of secondary charged particles produced by nucleus-nucleus interactions. In particular, using the modified G moments, which can be defined to suppress the statistical fluctuations, we study the intermittency in the low multiplicity processes produced by the 14.6-GeV/nucleon 28 Si - nucleus interactions. We have shown experimentally that the basic function B q,k (M), behaving as M λ(q,k) at large M, has the basic fractal behavior and that the exponent λ(q,k) depends linearly on the number of multiplicity in a bin

Study of XUV lasers produced by a CO/sub 2/ laser

International Nuclear Information System (INIS)

Daido, H.; Miura, E.; Kitagawa, Y.; Kato, Y.; Nishihara, K.; Sawai, K.; Nakai, S.S.; Yamanaka, C.

1988-01-01

The authors present recent progress at ILE, Osaka University in plasma recombination-pumped XUV lasers produced by a CO/sub 2/ laser. One way to produce large-population inversion with this scheme is rapid cooling of the gain medium keeping a high electron density, because the three-body recombination probability is proportional to the square of the electron density. The authors used a cylinder-type target made of 30-μm thick parylene (C/sub 8/H/sub 8/) whose diameter and length are 3 and 4 mm. The laser irradiated the 2500-A thick parylene foil attached to the center of the cylinder. The fully ablated plasma expands isotropically, producing an almost uniform plasma on the cylinder wall. Then the almost fully ionized carbon plasma is cooled by heat transport from the hot plasma to the wall. The estimated cooling time is a few nanoseconds assuming classical heat transport

Generation of Food-Grade Lactococcal Starters Which Produce the Lantibiotics Lacticin 3147 and Lacticin 481

Science.gov (United States)

O'Sullivan, Lisa; Ryan, Maire P.; Ross, R. Paul; Hill, Colin

2003-01-01

Transconjugant lactococcal starters which produce both lantibiotics lacticin 3147 and lacticin 481 were generated via conjugation of large bacteriocin-encoding plasmids. A representative of one of the resultant strains proved more effective at killing Lactobacillus fermentum and inhibiting the growth of Listeria monocytogenes LO28H than either of the single bacteriocin-producing parental strains, demonstrating the potential of these transconjugants as protection cultures for food safety applications. PMID:12788782

Mesoderm Lineage 3D Tissue Constructs Are Produced at Large-Scale in a 3D Stem Cell Bioprocess.

Science.gov (United States)

Cha, Jae Min; Mantalaris, Athanasios; Jung, Sunyoung; Ji, Yurim; Bang, Oh Young; Bae, Hojae

2017-09-01

Various studies have presented different approaches to direct pluripotent stem cell differentiation such as applying defined sets of exogenous biochemical signals and genetic/epigenetic modifications. Although differentiation to target lineages can be successfully regulated, such conventional methods are often complicated, laborious, and not cost-effective to be employed to the large-scale production of 3D stem cell-based tissue constructs. A 3D-culture platform that could realize the large-scale production of mesoderm lineage tissue constructs from embryonic stem cells (ESCs) is developed. ESCs are cultured using our previously established 3D-bioprocess platform which is amenable to mass-production of 3D ESC-based tissue constructs. Hepatocarcinoma cell line conditioned medium is introduced to the large-scale 3D culture to provide a specific biomolecular microenvironment to mimic in vivo mesoderm formation process. After 5 days of spontaneous differentiation period, the resulting 3D tissue constructs are composed of multipotent mesodermal progenitor cells verified by gene and molecular expression profiles. Subsequently the optimal time points to trigger terminal differentiation towards cardiomyogenesis or osteogenesis from the mesodermal tissue constructs is found. A simple and affordable 3D ESC-bioprocess that can reach the scalable production of mesoderm origin tissues with significantly improved correspondent tissue properties is demonstrated. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The European Union: When the Commission and Governments put the Future of Electricity Producers at Stake

International Nuclear Information System (INIS)

Lesourne, Jacques

2016-01-01

RWE, EON, EDF, ENGIE and other large utilities are in financial turmoil. This situation, which would have been unlikely twenty years ago, is related to several failures in governance within the EU as well as to global evolutions. This Edito Energie analyses the situation of large European electricity producers in light of the European energy policy

Application of carbon isotopes to detect seepage out of coalbed natural gas produced water impoundments

International Nuclear Information System (INIS)

Sharma, Shikha; Baggett, Joshua K.

2011-01-01

Highlights: → Coalbed natural gas extraction results in large amount of produced water. → Risk of deterioration of ambient water quality. → Carbon isotope natural tracer for detecting seepage from produced water impoundments. - Abstract: Coalbed natural gas (CBNG) production from coal bed aquifers requires large volumes of produced water to be pumped from the subsurface. The produced water ranges from high quality that meets state and federal drinking water standards to low quality due to increased salinity and/or sodicity. The Powder River Basin of northeastern Wyoming is a major coalbed natural gas producing region, where water quality generally decreases moving from the southeastern portion of the basin towards the center. Most produced water in Wyoming is disposed into impoundments and other surface drainages, where it may infiltrate into shallow groundwater. Groundwater degradation caused by infiltration of CBNG produced water holding impoundments into arid, soluble salt-rich soils is an issue of immense importance because groundwater is a major source for stock water, irrigation, and drinking water for many small communities in these areas. This study examines the potential of using stable C isotope signatures of dissolved inorganic C (δ 13 C DIC ) to track the fate of CBNG produced water after it is discharged into the impoundments. Other geochemical proxies like the major cations and major anions were used in conjunction with field water quality measurements to understand the geochemical differences between CBNG produced waters and ambient waters in the study area. Samples were collected from the CBNG discharge outfalls, produced water holding impoundments, and monitoring wells from different parts of the Powder River Basin and analyzed for δ 13 C DIC . The CBNG produced waters from outfalls and impoundments have positive δ 13 C DIC values that fall within the range of +12 per mille to +22 per mille, distinct from the ambient regional surface and

Clean-lifting transfer of large-area residual-free graphene films.

Science.gov (United States)

Wang, Di-Yan; Huang, I-Sheng; Ho, Po-Hsun; Li, Shao-Sian; Yeh, Yun-Chieh; Wang, Duan-Wei; Chen, Wei-Liang; Lee, Yu-Yang; Chang, Yu-Ming; Chen, Chia-Chun; Liang, Chi-Te; Chen, Chun-Wei

2013-08-27

A unique "clean-lifting transfer" (CLT) technique that applies a controllable electrostatic force to transfer large-area and high-quality CVD-grown graphene onto various rigid or flexible substrates is reported. The CLT technique without using any organic support or adhesives can produce residual-free graphene films with large-area processability, and has great potential for future industrial production of graphene-based electronics or optoelectronics. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Produced Water Reuse Considerations for In-Situ Recovery: a Case Development

Energy Technology Data Exchange (ETDEWEB)

Kus, J.; Card, R.

1984-01-01

Steam-assisted methods for in-situ recovery in Canada typically operate at steam to oil ratios of approximately 3 to 1 and generate in the order of 2 to 5 barrels of produced water per barrel of production. To raise the large quantities of steam required for reservoir stimulation, once-through type steam generators are most commonly used. They are typically designed to produce about 80 per cent quality steam from soft, oil-free feedwater. Suncor Inc operates a cyclic steam injection pilot project near Fort Kent, Alberta. In the early 1980s, Suncor planned an expansion of the 180 m/sup 3//d (1,130 bbl/d) facility to 800 m/sup 3//d (5,000 bbl/d). The expansion necessitated the development of a reliable water supply. Preliminary investigations into the feasibility of reusing produced water as the sole source of supply for the project expansion revealed this to be a costly and technically high risk option, given the specific produced water characteristics. As a result, an innovative alternative was developed to use a blend of produced water and municipal effluent from a nearby town as the water supply. This paper presents the rationale for the selection of this unique water supply and the process design considerations for the resulting water treatment system.

Large-scale seismic signal analysis with Hadoop

Science.gov (United States)

Addair, T. G.; Dodge, D. A.; Walter, W. R.; Ruppert, S. D.

2014-05-01

In seismology, waveform cross correlation has been used for years to produce high-precision hypocenter locations and for sensitive detectors. Because correlated seismograms generally are found only at small hypocenter separation distances, correlation detectors have historically been reserved for spotlight purposes. However, many regions have been found to produce large numbers of correlated seismograms, and there is growing interest in building next-generation pipelines that employ correlation as a core part of their operation. In an effort to better understand the distribution and behavior of correlated seismic events, we have cross correlated a global dataset consisting of over 300 million seismograms. This was done using a conventional distributed cluster, and required 42 days. In anticipation of processing much larger datasets, we have re-architected the system to run as a series of MapReduce jobs on a Hadoop cluster. In doing so we achieved a factor of 19 performance increase on a test dataset. We found that fundamental algorithmic transformations were required to achieve the maximum performance increase. Whereas in the original IO-bound implementation, we went to great lengths to minimize IO, in the Hadoop implementation where IO is cheap, we were able to greatly increase the parallelism of our algorithms by performing a tiered series of very fine-grained (highly parallelizable) transformations on the data. Each of these MapReduce jobs required reading and writing large amounts of data. But, because IO is very fast, and because the fine-grained computations could be handled extremely quickly by the mappers, the net was a large performance gain.

Large shaft development test plan

International Nuclear Information System (INIS)

Krug, A.D.

1984-03-01

This test plan proposes the conduct of a large shaft development test at the Hanford site in support of the repository development program. The purpose and objective of the test plan is to obtain the information necessary to establish feasibility and to predict the performance of the drilling system used to drill large diameter shafts. The test plan is based upon drilling a 20 ft diameter shaft to a depth of 1,000 feet. The test plan specifies series of tests to evaluate the performance of the downhole assembly, the performance of the rig, and the ability of the system to cope with geologic hazards. The quality of the hole produced will also be determined. This test plan is considered to be preliminary in that it was prepared as input for the decision to determine if development testing is required in this area. Should the decision be made to proceed with development testing, this test plan shall be updated and revised. 6 refs., 2 figs., 3 tabs

Soil fungal communities in a Castanea sativa (chestnut) forest producing large quantities of Boletus edulis sensu lato (porcini): where is the mycelium of porcini?

Science.gov (United States)

Peintner, Ursula; Iotti, Mirco; Klotz, Petra; Bonuso, Enrico; Zambonelli, Alessandra

2007-04-01

A study was conducted in a Castanea sativa forest that produces large quantities of the edible mushroom porcini (Boletus edulis sensu lato). The primary aim was to study porcini mycelia in the soil, and to determine if there were any possible ecological and functional interactions with other dominant soil fungi. Three different approaches were used: collection and morphological identification of fruiting bodies, morphological and molecular identification of ectomycorrhizae by rDNA-ITS sequence analyses and molecular identification of the soil mycelia by ITS clone libraries. Soil samples were taken directly under basidiomes of Boletus edulis, Boletus aestivalis, Boletus aereus and Boletus pinophilus. Thirty-nine ectomycorrhizal fungi were identified on root tips whereas 40 fungal species were found in the soil using the cloning technique. The overlap between above- and below-ground fungal communities was very low. Boletus mycelia, compared with other soil fungi, were rare and with scattered distribution, whereas their fruiting bodies dominated the above-ground fungal community. Only B. aestivalis ectomycorrhizae were relatively abundant and detected as mycelia in the soil. No specific fungus-fungus association was found. Factors triggering formation of mycorrhizae and fructification of porcini appear to be too complex to be simply explained on the basis of the amount of fungal mycelia in the soil.

A simple biosynthetic pathway for large product generation from small substrate amounts

Science.gov (United States)

Djordjevic, Marko; Djordjevic, Magdalena

2012-10-01

A recently emerging discipline of synthetic biology has the aim of constructing new biosynthetic pathways with useful biological functions. A major application of these pathways is generating a large amount of the desired product. However, toxicity due to the possible presence of toxic precursors is one of the main problems for such production. We consider here the problem of generating a large amount of product from a potentially toxic substrate. To address this, we propose a simple biosynthetic pathway, which can be induced in order to produce a large number of the product molecules, by keeping the substrate amount at low levels. Surprisingly, we show that the large product generation crucially depends on fast non-specific degradation of the substrate molecules. We derive an optimal induction strategy, which allows as much as three orders of magnitude increase in the product amount through biologically realistic parameter values. We point to a recently discovered bacterial immune system (CRISPR/Cas in E. coli) as a putative example of the pathway analysed here. We also argue that the scheme proposed here can be used not only as a stand-alone pathway, but also as a strategy to produce a large amount of the desired molecules with small perturbations of endogenous biosynthetic pathways.

A simple biosynthetic pathway for large product generation from small substrate amounts

Energy Technology Data Exchange (ETDEWEB)

Djordjevic, Marko [Institute of Physiology and Biochemistry, Faculty of Biology, University of Belgrade (Serbia); Djordjevic, Magdalena [Institute of Physics Belgrade, University of Belgrade (Serbia)

2012-10-01

A recently emerging discipline of synthetic biology has the aim of constructing new biosynthetic pathways with useful biological functions. A major application of these pathways is generating a large amount of the desired product. However, toxicity due to the possible presence of toxic precursors is one of the main problems for such production. We consider here the problem of generating a large amount of product from a potentially toxic substrate. To address this, we propose a simple biosynthetic pathway, which can be induced in order to produce a large number of the product molecules, by keeping the substrate amount at low levels. Surprisingly, we show that the large product generation crucially depends on fast non-specific degradation of the substrate molecules. We derive an optimal induction strategy, which allows as much as three orders of magnitude increase in the product amount through biologically realistic parameter values. We point to a recently discovered bacterial immune system (CRISPR/Cas in E. coli) as a putative example of the pathway analysed here. We also argue that the scheme proposed here can be used not only as a stand-alone pathway, but also as a strategy to produce a large amount of the desired molecules with small perturbations of endogenous biosynthetic pathways. (paper)

A simple biosynthetic pathway for large product generation from small substrate amounts

International Nuclear Information System (INIS)

Djordjevic, Marko; Djordjevic, Magdalena

2012-01-01

A recently emerging discipline of synthetic biology has the aim of constructing new biosynthetic pathways with useful biological functions. A major application of these pathways is generating a large amount of the desired product. However, toxicity due to the possible presence of toxic precursors is one of the main problems for such production. We consider here the problem of generating a large amount of product from a potentially toxic substrate. To address this, we propose a simple biosynthetic pathway, which can be induced in order to produce a large number of the product molecules, by keeping the substrate amount at low levels. Surprisingly, we show that the large product generation crucially depends on fast non-specific degradation of the substrate molecules. We derive an optimal induction strategy, which allows as much as three orders of magnitude increase in the product amount through biologically realistic parameter values. We point to a recently discovered bacterial immune system (CRISPR/Cas in E. coli) as a putative example of the pathway analysed here. We also argue that the scheme proposed here can be used not only as a stand-alone pathway, but also as a strategy to produce a large amount of the desired molecules with small perturbations of endogenous biosynthetic pathways. (paper)

Application-oriented research on plasma channeling of a large pulsed current

International Nuclear Information System (INIS)

Liu Jingye

2000-01-01

Utilizing the avalanche effect of plasma produced by the collision of energetic primary electrons with hydrogen molecules in a plasma, channeling of a large pulsed current is achieved, with the plasma acting as the carrier

LARGE-SCALE HYDROGEN PRODUCTION FROM NUCLEAR ENERGY USING HIGH TEMPERATURE ELECTROLYSIS

International Nuclear Information System (INIS)

O'Brien, James E.

2010-01-01

Hydrogen can be produced from water splitting with relatively high efficiency using high-temperature electrolysis. This technology makes use of solid-oxide cells, running in the electrolysis mode to produce hydrogen from steam, while consuming electricity and high-temperature process heat. When coupled to an advanced high temperature nuclear reactor, the overall thermal-to-hydrogen efficiency for high-temperature electrolysis can be as high as 50%, which is about double the overall efficiency of conventional low-temperature electrolysis. Current large-scale hydrogen production is based almost exclusively on steam reforming of methane, a method that consumes a precious fossil fuel while emitting carbon dioxide to the atmosphere. Demand for hydrogen is increasing rapidly for refining of increasingly low-grade petroleum resources, such as the Athabasca oil sands and for ammonia-based fertilizer production. Large quantities of hydrogen are also required for carbon-efficient conversion of biomass to liquid fuels. With supplemental nuclear hydrogen, almost all of the carbon in the biomass can be converted to liquid fuels in a nearly carbon-neutral fashion. Ultimately, hydrogen may be employed as a direct transportation fuel in a 'hydrogen economy.' The large quantity of hydrogen that would be required for this concept should be produced without consuming fossil fuels or emitting greenhouse gases. An overview of the high-temperature electrolysis technology will be presented, including basic theory, modeling, and experimental activities. Modeling activities include both computational fluid dynamics and large-scale systems analysis. We have also demonstrated high-temperature electrolysis in our laboratory at the 15 kW scale, achieving a hydrogen production rate in excess of 5500 L/hr.

Stable producer cell lines for adeno-associated virus (AAV) assembly.

Science.gov (United States)

Chadeuf, Gilliane; Salvetti, Anna

2010-10-01

Stable producer cell lines containing both the rep and cap genes and recombinant adeno-associated virus (rAAV) vectors can be infected with a helper virus to provide reliable and efficient production of rAAV stocks. However, the development of these cell lines is time-consuming. The procedure described here is therefore recommended only for studies requiring the production of high amounts of rAAV, such as preclinical studies performed in large animals.

Coalbed methane-produced water quality and its management options in Raniganj Basin, West Bengal, India

Science.gov (United States)

Mendhe, Vinod Atmaram; Mishra, Subhashree; Varma, Atul Kumar; Singh, Awanindra Pratap

2017-06-01

Coalbed methane (CBM) recovery is associated with production of large quantity of groundwater. The coal seams are depressurized by pumping of water for regular and consistent gas production. Usually, CBM operators need to pump >10 m3 of water per day from one well, which depends on the aquifer characteristics, drainage and recharge pattern. In India, 32 CBM blocks have been awarded for exploration and production, out of which six blocks are commercially producing methane gas at 0.5 million metric standard cubic feet per day. Large amount of water is being produced from CBM producing blocks, but no specific information or data are available for geochemical properties of CBM-produced water and its suitable disposal or utilization options for better management. CBM operators are in infancy and searching for the suitable solutions for optimal management of produced water. CBM- and mine-produced water needs to be handled considering its physical and geochemical assessment, because it may have environmental as well as long-term impact on aquifer. Investigations were carried out to evaluate geochemical and hydrogeological conditions of CBM blocks in Raniganj Basin. Totally, 15 water samples from CBM well head and nine water samples from mine disposal head were collected from Raniganj Basin. The chemical signature of produced water reveals high sodium and bicarbonate concentrations with low calcium and magnesium, and very low sulphate in CBM water. It is comprehend that CBM water is mainly of Na-HCO3 type and coal mine water is of Ca-Mg-SO4 and HCO3-Cl-SO4 type. The comparative studies are also carried out for CBM- and mine-produced water considering the geochemical properties, aquifer type, depth of occurrence and lithological formations. Suitable options like impounding, reverse osmosis, irrigation and industrial use after prerequisite treatments are suggested. However, use of this huge volume of CBM- and mine-produced water for irrigation or other beneficial purposes

Large Superconducting Magnet Systems

CERN Document Server

Védrine, P.

2014-07-17

The increase of energy in accelerators over the past decades has led to the design of superconducting magnets for both accelerators and the associated detectors. The use of Nb−Ti superconducting materials allows an increase in the dipole field by up to 10 T compared with the maximum field of 2 T in a conventional magnet. The field bending of the particles in the detectors and generated by the magnets can also be increased. New materials, such as Nb$_{3}$Sn and high temperature superconductor (HTS) conductors, can open the way to higher fields, in the range 13–20 T. The latest generations of fusion machines producing hot plasma also use large superconducting magnet systems.

Large Superconducting Magnet Systems

Energy Technology Data Exchange (ETDEWEB)

Védrine, P [Saclay (France)

2014-07-01

The increase of energy in accelerators over the past decades has led to the design of superconducting magnets for both accelerators and the associated detectors. The use of Nb−Ti superconducting materials allows an increase in the dipole field by up to 10 T compared with the maximum field of 2 T in a conventional magnet. The field bending of the particles in the detectors and generated by the magnets can also be increased. New materials, such as Nb3Sn and high temperature superconductor (HTS) conductors, can open the way to higher fields, in the range 13–20 T. The latest generations of fusion machines producing hot plasma also use large superconducting magnet systems.

Application of escape probability to line transfer in laser-produced plasmas

International Nuclear Information System (INIS)

Lee, Y.T.; London, R.A.; Zimmerman, G.B.; Haglestein, P.L.

1989-01-01

In this paper the authors apply the escape probability method to treat transfer of optically thick lines in laser-produced plasmas in plan-parallel geometry. They investigate the effect of self-absorption on the ionization balance and ion level populations. In addition, they calculate such effect on the laser gains in an exploding foil target heated by an optical laser. Due to the large ion streaming motion in laser-produced plasmas, absorption of an emitted photon occurs only over the length in which the Doppler shift is equal to the line width. They find that the escape probability calculated with the Doppler shift is larger compared to the escape probability for a static plasma. Therefore, the ion streaming motion contributes significantly to the line transfer process in laser-produced plasmas. As examples, they have applied escape probability to calculate transfer of optically thick lines in both ablating slab and exploding foil targets under irradiation of a high-power optical laser

Pulp mill as an energy producer

International Nuclear Information System (INIS)

Kaulamo, O.

1998-01-01

The recovery boilers of pulp mills are today the most significant producers of wood energy. The power-to-heat ratio of the power plant process, i.e., power yield, is poor in existing applications. In the study, an alternative of improving the power yield of conventional pulp mills significantly was studied by applying solutions used in power plants to a pulp mill. Extensive conversion of wood energy into electricity is possible only in the recovery boiler of the pulp mill and in a large combustion boiler of bark, wood waste and wood chips integrated to this boiler. Hence, the harvest and transports of wood raw materials, i.e. pulp wood and energy wood, are integrated, and the fraction going to cook and the energy wood fraction are separated at the pulp mill. The method guarantees competitive supply of energy wood. As a result a SELLUPOWER mill was designed, where the recovery boiler combusting black liquor and the large power plant boiler combusting energy wood are integrated to one unit and constructed to a power plant process with a high power-to-heat ratio. Necessary technical solutions, project costs and economical feasibility compared to a conventional pulp mill were determined, and the effect of different production-economical parameters was also studied. (orig.)

Dominance of IMP-4-Producing Enterobacter cloacae among Carbapenemase-Producing Enterobacteriaceae in Australia

Science.gov (United States)

Townell, Nicola; Nimmo, Graeme R.; George, Narelle M.; Robson, Jennifer; Vohra, Renu; Davis, Louise; Heney, Claire; Paterson, David L.

2015-01-01

The prevalence of carbapenemase-producing Enterobacteriaceae (CPE) has been increasing worldwide. blaIMP has been reported to be the predominant carbapenemase-encoding gene within Enterobacteriaceae in Australia. However, there are limited data currently available on CPE from Queensland, Australia. A total of 58 CPE isolates were isolated between July 2009 and March 2014 from Queensland hospitals. The clonality of isolates was determined by Diversilab repetitive sequence-based PCR. The isolates were investigated for the resistance mechanisms carbapenemase, extended-spectrum β-lactamase, and AmpC β-lactamase and for aminoglycoside resistance and plasmid-mediated quinolone resistance genes by PCR. The plasmid types associated with carbapenemase-encoding genes were characterized. The majority of the CPE were Enterobacter cloacae (n = 29). The majority of Queensland CPE isolates were IMP producers and comprised 11 species (n = 48). Nine NDM-producing Enterobacteriaceae were identified. One NDM-producing Klebsiella pneumoniae isolate coproduced OXA-48. One K. pneumoniae isolate was an OXA-181 producer. The incidence of IMP producers increased significantly in 2013. blaIMP-4 was found in all IMP-producing isolates. blaTEM, qnrB, and aacA4 were common among IMP-4 producers. The HI2 (67%) and L/M (21%) replicons were associated with blaIMP-4. All HI2 plasmids were of sequence type 1 (ST1). All but one of the NDM producers possessed blaCTX-M-15. The 16S rRNA methylase genes found among NDM producers were armA, rmtB, rmtC, and rmtF. The substantial increase in the prevalence of CPE in Queensland has been associated mainly with the emergence E. cloacae strains possessing HI2 plasmids carrying blaIMP-4 over the past 2 years. The importation of NDM producers and/or OXA-48-like producers in patients also contributed to the increased emergence of CPE. PMID:25918153

Hot seeding using large Y-123 seeds

International Nuclear Information System (INIS)

Scruggs, S J; Putman, P T; Zhou, Y X; Fang, H; Salama, K

2006-01-01

There are several motivations for increasing the diameter of melt textured single domain discs. The maximum magnetic field produced by a trapped field magnet is proportional to the radius of the sample. Furthermore, the availability of trapped field magnets with large diameter could enable their use in applications that have traditionally been considered to require wound electromagnets, such as beam bending magnets for particle accelerators and electric propulsion. We have investigated the possibility of using large area epitaxial growth instead of the conventional point nucleation growth mechanism. This process involves the use of large Y123 seeds for the purpose of increasing the maximum achievable Y123 single domain size. The hot seeding technique using large Y-123 seeds was employed to seed Y-123 samples. Trapped field measurements indicate that single domain samples were indeed grown by this technique. Microstructural evaluation indicates that growth can be characterized by a rapid nucleation followed by the usual peritectic grain growth which occurs when large seeds are used. Critical temperature measurements show that no local T c suppression occurs in the vicinity of the seed. This work supports the suggestion of using an iterative method for increasing the size of Y-123 single domains that can be grown

Development of large-capacity refrigeration at 1.8 K for the Large Hadron Collider at CERN

CERN Document Server

Lebrun, P; Claudet, G

1996-01-01

CERN, the European Laboratory for Particle Physics, is working towards the construction of the Large Hadron Collider (LHC), a high-energy, high-luminosity particle accelerator and collider [1] of 26.7 km circumference, due to start producing frontier physics, by bringing into collision intense proton and ion beams with centre-of-mass energies in the TeV-per-constituent range, at the beginning of the next century. The key technology for achieving this ambitious scientific goal at economically acceptable cost is the use of high-field superconducting magnets using Nb-Ti conductor operating in superfluid helium [2]. To maintain the some 25 km of bending and focusing magnets at their operating temperature of 1.9 K, the LHC cryogenic system will have to produce an unprecedented total refrigeration capacity of about 20 kW at 1.8 K, in eight cryogenic plants distributed around the machine circumference [3]. This has requested the undertaking of an industrial development programme, in the form of a collaboration betwe...

Large vessel imaging using cosmic-ray muons

International Nuclear Information System (INIS)

Jenneson, P.M.

2004-01-01

Cosmic-ray muons are assessed for their practical use in the tomographic imaging of the internal composition of large vessels over 2 m in diameter. The technique is based on the attenuation and scattering of cosmic-ray muons passing through a vessel and has advantages over photon-based methods of tomography that it is extendable to object containing high-density materials over many tens of metres. The main disadvantage is the length of time required to produce images of sufficient resolution and hence cosmic ray muon tomography will be most suited to the imaging of large structures whose internal composition is effectively static for the duration of the imaging period. Simulation and theoretical results are presented here which demonstrate the feasibility of cosmic ray muon tomography

Mineralogical, Microstructural and Thermal Characterization of Coal Fly Ash Produced from Kazakhstani Power Plants

Science.gov (United States)

Tauanov, Z.; Abylgazina, L.; Spitas, C.; Itskos, G.; Inglezakis, V.

2017-09-01

Coal fly ash (CFA) is a waste by-product of coal combustion. Kazakhstan has vast coal deposits and is major consumer of coal and hence produces huge amounts of CFA annually. The government aims to recycle and effectively utilize this waste by-product. Thus, a detailed study of the physical and chemical properties of material is required as the data available in literature is either outdated or not applicable for recently produced CFA samples. The full mineralogical, microstructural and thermal characterization of three types of coal fly ash (CFA) produced in two large Kazakhstani power plants is reported in this work. The properties of CFAs were compared between samples as well as with published values.

No large scale curvature perturbations during the waterfall phase transition of hybrid inflation

International Nuclear Information System (INIS)

Abolhasani, Ali Akbar; Firouzjahi, Hassan

2011-01-01

In this paper the possibility of generating large scale curvature perturbations induced from the entropic perturbations during the waterfall phase transition of the standard hybrid inflation model is studied. We show that whether or not appreciable amounts of large scale curvature perturbations are produced during the waterfall phase transition depends crucially on the competition between the classical and the quantum mechanical backreactions to terminate inflation. If one considers only the classical evolution of the system, we show that the highly blue-tilted entropy perturbations induce highly blue-tilted large scale curvature perturbations during the waterfall phase transition which dominate over the original adiabatic curvature perturbations. However, we show that the quantum backreactions of the waterfall field inhomogeneities produced during the phase transition dominate completely over the classical backreactions. The cumulative quantum backreactions of very small scale tachyonic modes terminate inflation very efficiently and shut off the curvature perturbation evolution during the waterfall phase transition. This indicates that the standard hybrid inflation model is safe under large scale curvature perturbations during the waterfall phase transition.

Fuel characteristics and trace gases produced through biomass burning

Directory of Open Access Journals (Sweden)

BAMBANG HERO SAHARJO

2010-01-01

Full Text Available Saharjo BH, Sudo S, Yonemura S, Tsuruta H (2010 Fuel characteristics and trace gases produced through biomass burning. Biodiversitas 11: 40-45. Indonesian 1997/1998 forest fires resulted in forest destruction totally 10 million ha with cost damaged about US$ 10 billion, where more than 1 Gt CO2 has been released during the fire episode and elevating Indonesia to one of the largest polluters of carbon in the world where 22% of world’s carbon dioxide produced. It has been found that 80-90% of the fire comes from estate crops and industrial forest plantation area belongs to the companies which using fire illegally for the land preparation. Because using fire is cheap, easy and quick and also support the companies purpose in achieving yearly planted area target. Forest management and land use practices in Sumatra and Kalimantan have evolved very rapidly over the past three decades. Poor logging practices resulted in large amounts of waste will left in the forest, greatly elevating fire hazard. Failure by the government and concessionaires to protect logged forests and close old logging roads led to and invasion of the forest by agricultural settlers whose land clearances practices increased the risk of fire. Several field experiments had been done in order to know the quality and the quantity of trace produced during biomass burning in peat grass, peat soil and alang-alang grassland located in South Sumatra, Indonesia. Result of research show that different characteristics of fuel burned will have the different level also in trace gasses produced. Peat grass with higher fuel load burned produce more trace gasses compared to alang-alang grassland and peat soil.

The importance of creating a social business to produce low-cost hearing aids.

Science.gov (United States)

Caccamo, Samantha; Voloshchenko, Anastasia; Dankyi, Nana Yaa

2014-09-01

The World Health Organization (WHO) estimates that about 280 million people worldwide have a bilateral hearing loss, mostly living in poor countries. Hearing loss causes heavy social burdens on individuals, families, communities and countries. However, due to the lack of accessibility and affordability, the vast majority of people in the world who need hearing aids do not have access to them. Low-income countries are thus pulled into a disability/poverty spiral. From this standpoint, the production of available, accessible and affordable hearing aids for the poorest populations of our planet should be one of the main issues in global hearing healthcare. Designing and producing a brand new low-cost hearing aid is the most effective option. Involving a large producer of hearing aids in the creation of a social business to solve the problem of access to affordable hearing aids is an essential step to reduce hearing disability on a large scale globally. Today's technology allows for the creation of a "minimal design" product that does not exceed $100-$150, that can be further lowered when purchased in large quantities and dispensed with alternative models. It is conceivable that by making a sustainable social business, the low cost product could be sold with a cross-subsidy model in order to recover the overhead costs. Social business is an economic model that has the potential to produce and distribute affordable hearing aids in low- and middle-income countries. Rehabilitation of hearing impaired children will be carried out in partnership with Sahic (Society of Assistance to Hearing Impaired Children) in Dhaka, Bangladesh and the ENT Department of Ospedale Burlo di Trieste, Dr. Eva Orzan.

Imbalance costs in the Swedish system with large amounts of wind power

Energy Technology Data Exchange (ETDEWEB)

Carlsson, Fredrik; Neimane, Viktoria [Vattenfall Research and Development AB, Stockholm (Sweden)

2009-07-01

The well-known concerns about wind power are related to its intermittent nature and difficulty to make exact forecasts. The expected increase in balancing and reserve requirements due to wind power has been investigated in several studies. This paper takes the next step in studying integration of large amounts of wind power in Sweden. Several wind power producers' and corresponding balance providers' perspective is taken and their imbalance costs modeled. Larger producers having wind power spread over larger geographical areas will have lower relative costs than producers having their units concentrated within limited geographical area. Possibilities of the wind power producers to reduce the imbalance costs by acting on after sales market are exposed and compared. (orig.)

Producing charcoal from wastes

Energy Technology Data Exchange (ETDEWEB)

Pogorelov, V.A.

1983-01-01

Experimental works to use wood wastes for producing charcoal are examined, which are being conducted in the Sverdlovsk assembly and adjustment administration of Soyuzorglestekhmontazh. A wasteless prototype installation for producing fine charcoal is described, along with its subsequent briqueting, which is made on the basis of units which are series produced by the factories of the country. The installation includes subassemblies for preparing and drying the raw material and for producing the charcoal briquets. In the opinion of specialists, the charcoal produced from the wastes may be effectively used in ferrous and nonferrous metallurgy and in the production of pipes.

On the stability of large-area Al-p-Si junction

International Nuclear Information System (INIS)

Tsyganov, Yu.S.

2006-01-01

Design of silicon radiation detector made of 12 kΩ · cm p-silicon with both amine- and amine-free hardeners epoxy resin junction edge passivation is presented. Before producing large-area detectors for measurements of efficiency of evaporation residues collection at the focal plane of the Dubna Gas-Filled Recoil Separator (DGFRS), a set of small-area test detectors was produced. Stability of the Al-(p)Si junction has been studied for a long time. Estimate of a realistic lifetime for the mentioned type of Al-Si rectifying junction is done

Salmonellosis outbreaks in the United States due to fresh produce: sources and potential intervention measures.

Science.gov (United States)

Hanning, Irene B; Nutt, J D; Ricke, Steven C

2009-01-01

Foodborne Salmonella spp. is a leading cause of foodborne illness in the United States each year. Traditionally, most cases of salmonellosis were thought to originate from meat and poultry products. However, an increasing number of salmonellosis outbreaks are occurring as a result of contaminated produce. Several produce items specifically have been identified in outbreaks, and the ability of Salmonella to attach or internalize into vegetables and fruits may be factors that make these produce items more likely to be sources of Salmonella. In addition, environmental factors including contaminated water sources used to irrigate and wash produce crops have been implicated in a large number of outbreaks. Salmonella is carried by both domesticated and wild animals and can contaminate freshwater by direct or indirect contact. In some cases, direct contact of produce or seeds with contaminated manure or animal wastes can lead to contaminated crops. This review examines outbreaks of Salmonella due to contaminated produce, the potential sources of Salmonella, and possible control measures to prevent contamination of produce.

Bursting and large-scale intermittency in turbulent convection with differential rotation

International Nuclear Information System (INIS)

Garcia, O.E.; Bian, N.H.

2003-01-01

The tilting mechanism, which generates differential rotation in two-dimensional turbulent convection, is shown to produce relaxation oscillations in the mean flow energy integral and bursts in the global fluctuation level, akin to Lotka-Volterra oscillations. The basic reason for such behavior is the unidirectional and conservative transfer of kinetic energy from the fluctuating motions to the mean component of the flows, and its dissipation at large scales. Results from numerical simulations further demonstrate the intimate relation between these low-frequency modulations and the large-scale intermittency of convective turbulence, as manifested by exponential tails in single-point probability distribution functions. Moreover, the spatio-temporal evolution of convective structures illustrates the mechanism triggering avalanche events in the transport process. The latter involves the overlap of delocalized mixing regions when the barrier to transport, produced by the mean component of the flow, transiently disappears

Volatiles produced by Staphylococcus xylosus and Staphylococcus carnosus during growth in sausage minces

DEFF Research Database (Denmark)

Stahnke, Marie Louise Heller

1999-01-01

Aseptic model minces were inoculated with commercial samples of either Staphylococcus xylosus or Staphylococcus carnosus. Volatiles produced by the cultures were collected during growth by diffusive sampling onto adsorbent traps, identified by thermal desorption-gas chromatography-mass spectrometry...... and quantified by thermal desorption-gas chromatography-flame ionisation. The data were analysed by principal component analysis. The study showed that both starter cultures produced a large number of volatiles in concentrations of sensory importance. Almost all of the major volatiles resulted from amino acid...... degradation, suggesting that the effect of Staphylococcus starter cultures on flavour quality is much related to their ability of catabolizing amino acids. With the exception of diacetyl, acetoin and 2-methyl-1-butanol, both cultures formed the same volatiles. Diacetyl and acetoin were not produced...

Forecasting distribution of numbers of large fires

Science.gov (United States)

Eidenshink, Jeffery C.; Preisler, Haiganoush K.; Howard, Stephen; Burgan, Robert E.

2014-01-01

Systems to estimate forest fire potential commonly utilize one or more indexes that relate to expected fire behavior; however they indicate neither the chance that a large fire will occur, nor the expected number of large fires. That is, they do not quantify the probabilistic nature of fire danger. In this work we use large fire occurrence information from the Monitoring Trends in Burn Severity project, and satellite and surface observations of fuel conditions in the form of the Fire Potential Index, to estimate two aspects of fire danger: 1) the probability that a 1 acre ignition will result in a 100+ acre fire, and 2) the probabilities of having at least 1, 2, 3, or 4 large fires within a Predictive Services Area in the forthcoming week. These statistical processes are the main thrust of the paper and are used to produce two daily national forecasts that are available from the U.S. Geological Survey, Earth Resources Observation and Science Center and via the Wildland Fire Assessment System. A validation study of our forecasts for the 2013 fire season demonstrated good agreement between observed and forecasted values.

Intrastate conflict in oil producing states: A threat to global oil supply?

International Nuclear Information System (INIS)

Toft, Peter

2011-01-01

In this paper I investigate how often and how much outbreaks of intrastate conflict in oil producing states translates into oil supply shortfalls. The Libyan conflict that broke out in February 2011 highlighted the fear that intrastate conflict in oil producing states may imply shortfalls and ensuing volatile global oil prices. I argue, however, that it is far from certain that shortfalls following conflict outbreak will occur, since both sides in a conflict face incentives simultaneously to protect and maintain oil installations and to strike and destroy these. Based on a quantitative analysis of 39 intrastate wars in oil producing countries (1965-2007) I conclude that outbreak of conflict does not translate into production decline with any certainty. In fact, likelihoods are less than 50% for reductions to occur. In many cases growing production actually followed conflict outbreak. I conclude by investigating four characteristics of intrastate conflict that may explain when oil production is at risk during conflict: (1) proximity of oil producing fields to key battle zones, (2) duration of conflict, (3) separatism and the location of oil in separatist territory, and (4) the relative size of oil production. While the first three factors did not prove important, oil producer size could be significant. But further research is needed to establish this with greater certainty. - Highlights: → Oil shortfall during intrastate conflict is not a given. → Statistical analysis of 39 intrastate conflicts in oil producing countries since 1965. → Examination of four characteristics of intrastate conflict in oil producing countries. → Marginal significance related to large producers and production shortfall.

Intrastate conflict in oil producing states: A threat to global oil supply?

Energy Technology Data Exchange (ETDEWEB)

Toft, Peter, E-mail: peter.toft@ec.europa.eu [Institute for Energy, Joint Research Centre of the European Commission, Westerduinweg 3, 1755 ZG Petten (Netherlands)

2011-11-15

In this paper I investigate how often and how much outbreaks of intrastate conflict in oil producing states translates into oil supply shortfalls. The Libyan conflict that broke out in February 2011 highlighted the fear that intrastate conflict in oil producing states may imply shortfalls and ensuing volatile global oil prices. I argue, however, that it is far from certain that shortfalls following conflict outbreak will occur, since both sides in a conflict face incentives simultaneously to protect and maintain oil installations and to strike and destroy these. Based on a quantitative analysis of 39 intrastate wars in oil producing countries (1965-2007) I conclude that outbreak of conflict does not translate into production decline with any certainty. In fact, likelihoods are less than 50% for reductions to occur. In many cases growing production actually followed conflict outbreak. I conclude by investigating four characteristics of intrastate conflict that may explain when oil production is at risk during conflict: (1) proximity of oil producing fields to key battle zones, (2) duration of conflict, (3) separatism and the location of oil in separatist territory, and (4) the relative size of oil production. While the first three factors did not prove important, oil producer size could be significant. But further research is needed to establish this with greater certainty. - Highlights: > Oil shortfall during intrastate conflict is not a given. > Statistical analysis of 39 intrastate conflicts in oil producing countries since 1965. > Examination of four characteristics of intrastate conflict in oil producing countries. > Marginal significance related to large producers and production shortfall.

Microbiota-Produced Succinate Improves Glucose Homeostasis via Intestinal Gluconeogenesis

DEFF Research Database (Denmark)

De Vadder, Filipe; Kovatcheva-Datchary, Petia; Zitoun, Carine

2016-01-01

Beneficial effects of dietary fiber on glucose and energy homeostasis have long been described, focusing mostly on the production of short-chain fatty acids by the gut commensal bacteria. However, bacterial fermentation of dietary fiber also produces large amounts of succinate and, to date......, no study has focused on the role of succinate on host metabolism. Here, we fed mice a fiber-rich diet and found that succinate was the most abundant carboxylic acid in the cecum. Dietary succinate was identified as a substrate for intestinal gluconeogenesis (IGN), a process that improves glucose...

Facile Large-scale synthesis of stable CuO nanoparticles

Science.gov (United States)

Nazari, P.; Abdollahi-Nejand, B.; Eskandari, M.; Kohnehpoushi, S.

2018-04-01

In this work, a novel approach in synthesizing the CuO nanoparticles was introduced. A sequential corrosion and detaching was proposed in the growth and dispersion of CuO nanoparticles in the optimum pH value of eight. The produced CuO nanoparticles showed six nm (±2 nm) in diameter and spherical feather with a high crystallinity and uniformity in size. In this method, a large-scale production of CuO nanoparticles (120 grams in an experimental batch) from Cu micro-particles was achieved which may met the market criteria for large-scale production of CuO nanoparticles.

Extraction Tools for Identification of Chemical Contaminants in Estuarine and Coastal Waters to Determine Toxic Pressure on Primary Producers

NARCIS (Netherlands)

Booij, P; Sjollema, S.B.; Leonards, P.E.G.; de Voogt, P.; Stroomberg, G.J.; Vethaak, A.D.; Lamoree, M.H.

2013-01-01

The extent to which chemical stressors affect primary producers in estuarine and coastal waters is largely unknown. However, given the large number of legacy pollutants and chemicals of emerging concern present in the environment, this is an important and relevant issue that requires further study.

Rotation invariant fast features for large-scale recognition

Science.gov (United States)

Takacs, Gabriel; Chandrasekhar, Vijay; Tsai, Sam; Chen, David; Grzeszczuk, Radek; Girod, Bernd

2012-10-01

We present an end-to-end feature description pipeline which uses a novel interest point detector and Rotation- Invariant Fast Feature (RIFF) descriptors. The proposed RIFF algorithm is 15× faster than SURF1 while producing large-scale retrieval results that are comparable to SIFT.2 Such high-speed features benefit a range of applications from Mobile Augmented Reality (MAR) to web-scale image retrieval and analysis.

Characterizing large river sounds: Providing context for understanding the environmental effects of noise produced by hydrokinetic turbines.

Science.gov (United States)

Bevelhimer, Mark S; Deng, Z Daniel; Scherelis, Constantin

2016-01-01

Underwater noise associated with the installation and operation of hydrokinetic turbines in rivers and tidal zones presents a potential environmental concern for fish and marine mammals. Comparing the spectral quality of sounds emitted by hydrokinetic turbines to natural and other anthropogenic sound sources is an initial step at understanding potential environmental impacts. Underwater recordings were obtained from passing vessels and natural underwater sound sources in static and flowing waters. Static water measurements were taken in a lake with minimal background noise. Flowing water measurements were taken at a previously proposed deployment site for hydrokinetic turbines on the Mississippi River, where sounds created by flowing water are part of all measurements, both natural ambient and anthropogenic sources. Vessel sizes ranged from a small fishing boat with 60 hp outboard motor to an 18-unit barge train being pushed upstream by tugboat. As expected, large vessels with large engines created the highest sound levels, which were, on average, 40 dB greater than the sound created by an operating hydrokinetic turbine. A comparison of sound levels from the same sources at different distances using both spherical and cylindrical sound attenuation functions suggests that spherical model results more closely approximate observed sound attenuation.

Consumers and Producers

NARCIS (Netherlands)

E. Maira (Elisa)

2018-01-01

markdownabstractIn the last few decades, advances in information and communication technology have dramatically changed the way consumers and producers interact in the marketplace. The Internet and social media have torn down the information barrier between producers and consumers, leading to

Producing energy from cardboard factory waste, Finding sustainable solutions for handling non-recyclable waste

NARCIS (Netherlands)

Dijkstra, Thijs

2008-01-01

Eska Graphic Board is a cardboard factory which requires large amounts of energy in the form of heat for the production of graphical cardboard. Currently, Eska has on-site gas powered boilers to produce heat and a combined-heat-and-power (CHP) system to p

Enzymes and bioproducts produced by the ascomycete fungus Paecilomyces variotii.

Science.gov (United States)

Herrera Bravo de Laguna, I; Toledo Marante, F J; Mioso, R

2015-12-01

Due its innate ability to produce extracellular enzymes which can provide eco-friendly solutions for a variety of biotechnological applications, Paecilomyces variotii is a potential source of industrial bioproducts. In this review, we report biotechnological records on the biochemistry of different enzymes produced by the fermentation of the P. variotii fungus, including tannases, phytases, cellulases, xylanases, chitinases, amylases and pectinases. Additionally, the main physicochemical properties which can affect the enzymatic reactions of the enzymes involved in the conversion of a huge number of substrates to high-value bioproducts are described. Despite all the background information compiled in this review, more research is required to consolidate the catalytic efficiency of P. variotii, which must be optimized so that it is more accurate and reproducible on a large scale. © 2015 The Society for Applied Microbiology.

Possible future effects of large-scale algae cultivation for biofuels on coastal eutrophication in Europe

NARCIS (Netherlands)

Blaas, H.; Kroeze, C.

2014-01-01

Biodiesel is increasingly considered as an alternative for fossil diesel. Biodiesel can be produced from rapeseed, palm, sunflower, soybean and algae. In this study, the consequences of large-scale production of biodiesel from micro-algae for eutrophication in four large European seas are analysed.

Biologically produced sulfur

NARCIS (Netherlands)

Kleinjan, W.E.; Keizer, de A.; Janssen, A.J.H.

2003-01-01

Sulfur compound oxidizing bacteria produce sulfur as an intermediate in the oxidation of hydrogen sulfide to sulfate. Sulfur produced by these microorganisms can be stored in sulfur globules, located either inside or outside the cell. Excreted sulfur globules are colloidal particles which are

Side effects of problem-solving strategies in large-scale nutrition science: towards a diversification of health.

Science.gov (United States)

Penders, Bart; Vos, Rein; Horstman, Klasien

2009-11-01

Solving complex problems in large-scale research programmes requires cooperation and division of labour. Simultaneously, large-scale problem solving also gives rise to unintended side effects. Based upon 5 years of researching two large-scale nutrigenomic research programmes, we argue that problems are fragmented in order to be solved. These sub-problems are given priority for practical reasons and in the process of solving them, various changes are introduced in each sub-problem. Combined with additional diversity as a result of interdisciplinarity, this makes reassembling the original and overall goal of the research programme less likely. In the case of nutrigenomics and health, this produces a diversification of health. As a result, the public health goal of contemporary nutrition science is not reached in the large-scale research programmes we studied. Large-scale research programmes are very successful in producing scientific publications and new knowledge; however, in reaching their political goals they often are less successful.

Membrane Technology for Produced Water in Lea County

Energy Technology Data Exchange (ETDEWEB)

Cecilia Nelson; Ashok Ghosh

2011-06-30

Southeastern New Mexico (SENM) is rich in mineral resources, including oil and gas. Produced water is a byproduct from oil and gas recovery operations. SENM generates approximately 400 million barrels per year of produced water with total dissolved solids (TDS) as high as ~ 200,000 ppm. Typically, produced water is disposed of by transporting it to injection wells or disposal ponds, costing around $1.2 billion per year with an estimated use of 0.3 million barrels of transportation fuel. New Mexico ranks first among U.S. states in potash production. Nationally, more than 85% of all potash produced comes from the Carlsbad potash district in SENM. Potash manufacturing processes use large quantities of water, including fresh water, for solution mining. If the produced water from oilfield operations can be treated and used economically in the potash industry, it will provide a beneficial use for the produced water as well as preserve valuable water resources in an area where fresh water is scarce. The goal of this current research was to develop a prototype desalination system that economically treats produced water from oil and/or natural gas operations for the beneficial use of industries located in southeastern New Mexico. Up until now, most water cleaning technologies have been developed for treating water with much lower quantities of TDS. Seawater with TDS of around 30,000 ppm is the highest concentration that has been seriously studied by researchers. Reverse osmosis (RO) technology is widely used; however the cost remains high due to high-energy consumption. Higher water fluxes and recoveries are possible with a properly designed Forward Osmosis (FO) process as large driving forces can be induced with properly chosen membranes and draw solution. Membrane fouling and breakdown is a frequent and costly problem that drives the cost of desalination very high. The technology developed by New Mexico Tech (NMT) researchers not only protects the membrane, but has also

First results on material identification and imaging with a large-volume muon tomography prototype

Energy Technology Data Exchange (ETDEWEB)

Pesente, S. [INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy); Vanini, S. [University of Padova and INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy)], E-mail: sara.vanini@pd.infn.it; Benettoni, M. [INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy); Bonomi, G. [University of Brescia, via Branze 38, 25123 Brescia and INFN Sezione di Pavia, via Bassi 6, 27100 Pavia (Italy); Calvini, P. [University of Genova and INFN Sezione di Genova, via Dodecaneso 33, 16146 Genova (Italy); Checchia, P.; Conti, E.; Gonella, F.; Nebbia, G. [INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy); Squarcia, S. [University of Genova and INFN Sezione di Genova, via Dodecaneso 33, 16146 Genova (Italy); Viesti, G. [University of Padova and INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy); Zenoni, A. [University of Brescia, via Branze 38, 25123 Brescia and INFN Sezione di Pavia, via Bassi 6, 27100 Pavia (Italy); Zumerle, G. [University of Padova and INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy)

2009-06-11

The muon tomography technique, based on the Multiple Coulomb Scattering of cosmic ray muons, has been proposed recently as a tool to perform non-destructive assays of large-volume objects without any radiation hazard. In this paper we discuss experimental results obtained with a scanning system prototype, assembled using two large-area CMS Muon Barrel drift chambers. The capability of the apparatus to produce 3D images of objects and to classify them according to their density is presented. We show that the absorption of low-momentum muons in the scanned objects produces an underestimate of their scattering density, making the discrimination of materials heavier than lead more difficult.

Case Report: Nodule Development From Subcapsular Aldosterone-Producing Cell Clusters Causes Hyperaldosteronism.

Science.gov (United States)

Nishimoto, Koshiro; Seki, Tsugio; Kurihara, Isao; Yokota, Kenichi; Omura, Masao; Nishikawa, Tetsuo; Shibata, Hirotaka; Kosaka, Takeo; Oya, Mototsugu; Suematsu, Makoto; Mukai, Kuniaki

2016-01-01

We previously reported that the human adrenal cortex remodels to form subcapsular aldosterone-producing cell clusters (APCCs). Some APCCs were recently found to carry aldosterone-producing adenoma (APA)-associated somatic mutations in ion channel/pump genes, which implied that APCCs produce aldosterone autonomously and are an origin of APA. However, there has been no report describing an APCC-to-APA transitional lesion. A histological examination revealed unilateral multiple adrenocortical micronodules in the adrenals of two patients with primary aldosteronism (PA). Based on immunohistochemistry for aldosterone synthase, some of the micronodules were identified as possible APCC-to-APA transitional lesions (pAATLs; a tentative term used in this manuscript), which consisted of a subcapsular APCC-like portion and an inner micro-APA-like (mAPA-like) portion without an apparent histological border. Genomic DNA samples prepared from pAATL histological sections were analyzed by next-generation sequencing for the known APA-associated mutations. The mAPA-like portions from two of the three large pAATLs examined harbored mutations (KCNJ5 [p.G151R] in pAATL 3 and ATP1A1 [p.L337M] in pAATL 7), whereas their corresponding APCC-like portions did not, suggesting their role in the formation of mAPA. Another lesion carried novel mutations in ATP1A1 (p.Ile322_Ile325del and p.Ile327Ser) in both the mAPA-like and APCC-like portions, thereby supporting these portions having a clonal origin. A novel aldosterone-producing pathology, pAATL that causes unilateral PA, was detected in the adrenals of two patients. Next-generation sequencing analyses of the large pAATLs suggested that the introduction of APA-associated mutations in the ion channel/pump genes may be involved in the development of mAPA from existing APCCs.

Some effects of integrated production planning in large-scale kitchens

DEFF Research Database (Denmark)

Engelund, Eva Høy; Friis, Alan; Jacobsen, Peter

2005-01-01

Integrated production planning in large-scale kitchens proves advantageous for increasing the overall quality of the food produced and the flexibility in terms of a diverse food supply. The aim is to increase the flexibility and the variability in the production as well as the focus on freshness ...

Seafloor mapping of large areas using multibeam system - Indian experience

Digital Repository Service at National Institute of Oceanography (India)

Kodagali, V.N.; KameshRaju, K.A; Ramprasad, T.

averaged and merged to produce large area maps. Maps were generated in the scale of 1 mil. and 1.5 mil covering area of about 2 mil. sq.km in single map. Also, depth contour interval were generated. A computer program was developed to convert the depth data...

An algebraic sub-structuring method for large-scale eigenvalue calculation

International Nuclear Information System (INIS)

Yang, C.; Gao, W.; Bai, Z.; Li, X.; Lee, L.; Husbands, P.; Ng, E.

2004-01-01

We examine sub-structuring methods for solving large-scale generalized eigenvalue problems from a purely algebraic point of view. We use the term 'algebraic sub-structuring' to refer to the process of applying matrix reordering and partitioning algorithms to divide a large sparse matrix into smaller submatrices from which a subset of spectral components are extracted and combined to provide approximate solutions to the original problem. We are interested in the question of which spectral components one should extract from each sub-structure in order to produce an approximate solution to the original problem with a desired level of accuracy. Error estimate for the approximation to the smallest eigenpair is developed. The estimate leads to a simple heuristic for choosing spectral components (modes) from each sub-structure. The effectiveness of such a heuristic is demonstrated with numerical examples. We show that algebraic sub-structuring can be effectively used to solve a generalized eigenvalue problem arising from the simulation of an accelerator structure. One interesting characteristic of this application is that the stiffness matrix produced by a hierarchical vector finite elements scheme contains a null space of large dimension. We present an efficient scheme to deflate this null space in the algebraic sub-structuring process

Can pions created in high-energy heavy-ion collisions produce a Centauro-type effect?

International Nuclear Information System (INIS)

Martinis, M.; Mikuta-Martinis, V.; Crnugelj, J.

1995-01-01

We study a Centauro-type phenomenon in high-energy heavy-ion collisions by assuming that pions are produced semiclassically both directly and in pairs through the isovector channel. The leading-particle effect and the factorization property of the scattering amplitude in the impact-parameter space are used to define the classical pion field. We show that the Centauro-type effect is strongly suppressed if a large number of pions are produced in isovector pairs. Our conclusion is supported through the calculation of two pion correlation parameters, f 2 0- and f 2 00 , as well as f 2, n - 0 and the average number of neutral pions (left-angle n 0 right-angle n- ) a a function of negative pions (n - ) produced

Large-scale melting and impact mixing on early-formed asteroids

DEFF Research Database (Denmark)

Greenwood, Richard; Barrat, J.-A.; Scott, Edward Robert Dalton

Large-scale melting of asteroids and planetesimals is now known to have taken place ex-tremely early in solar system history [1]. The first-generation bodies produced by this process would have been subject to rapid collisional reprocessing, leading in most cases to fragmentation and/or accretion...... the relationship between the different groups of achondrites [3, 4]. Here we present new oxygen isotope evidence con-cerning the role of large-scale melting and subsequent impact mixing in the evolution of three important achondrite groups: the main-group pallasites, meso-siderites and HEDs....

Intrinsic rotation produced by ion orbit loss and X-loss

Energy Technology Data Exchange (ETDEWEB)

Stacey, W. M. [Georgia Institute of Technology, Atlanta, Georgia 30332 (United States); Boedo, J. A. [University of California - San Diego, San Diego, California 92093 (United States); Evans, T. E.; Groebner, R. J. [General Atomics, San Diego, California 92186 (United States); Grierson, B. A. [Princeton Plasma Physics Laboratory, Princeton, New Jersey 08453 (United States)

2012-11-15

A practical calculation model for the intrinsic rotation imparted to the edge plasma by the directionally preferential loss of ions on orbits that cross the last closed flux surface is presented and applied to calculate intrinsic rotation in several DIII-D [J. Luxon, Nucl. Fusion 42, 614 (2002)] discharges. The intrinsic rotation produced by ion loss is found to be sensitive to the edge temperature and radial electric field profiles, which has implications for driving intrinsic rotation in future large tokamaks.

Characteristics of plasma in uranium atomic beam produced by electron-beam heating

International Nuclear Information System (INIS)

Ohba, Hironori; Shibata, Takemasa

2000-08-01

The electron temperature of plasma and the ion flux ratio in the uranium atomic beam produced by electron-beam heating were characterized with Langmuir probes. The electron temperature was 0.13 eV, which was lower than the evaporation surface temperature. The ion flux ratio to atomic beam flux was more than 3% at higher evaporation rates. The ion flux ratio has increased with decreasing acceleration energy of the electron-beam under constant electron-beam power. This is because of an increase of electron-beam current and a large ionization cross-section of uranium by electron-impact. It was confined that the plasma is produced by electron-impact ionization of the evaporated atoms at the evaporation source. (author)

A review of crosslinked fracturing fluids prepared with produced water

Directory of Open Access Journals (Sweden)

Leiming Li

2016-12-01

Full Text Available The rapidly increasing implementations of oilfield technologies such as horizontal wells and multistage hydraulic fracturing, particularly in unconventional formations, have expanded the need for fresh water in many oilfield locations. In the meantime, it is costly for services companies and operators to properly dispose large volumes of produced water, generated annually at about 21 billion barrels in the United States alone. The high operating costs in obtaining fresh water and dealing with produced water have motivated scientists and engineers, especially in recent years, to use produced water in place of fresh water to formulate well treatment fluids. The objective of this brief review is to provide a summary of the up-to-date technologies of reusing oilfield produced water in preparations of a series of crosslinked fluids implemented mainly in hydraulic fracturing operations. The crosslinked fluids formulated with produced water include borate- and metal-crosslinked guar and derivatized guar fluids, as well as other types of crosslinked fluid systems such as crosslinked synthetic polymer fluids and crosslinked derivatized cellulose fluids. The borate-crosslinked guar fluids have been successfully formulated with produced water and used in oilfield operations with bottomhole temperatures up to about 250 °F. The produced water sources involved showed total dissolved solids (TDS up to about 115,000 mg/L and hardness up to about 11,000 mg/L. The metal-crosslinked guar fluids prepared with produced water were successfully used in wells at bottomhole temperatures up to about 250 °F, with produced water TDS up to about 300,000 mg/L and hardness up to about 44,000 mg/L. The Zr-crosslinked carboxymethyl hydroxypropyl guar (CMHPG fluids have been successfully made with produced water and implemented in operations with bottomhole temperatures at about 250+ °F, with produced water TDS up to about 280,000 mg/L and hardness up to about 91,000�

Selective laser melting-produced porous titanium scaffolds regenerate bone in critical size cortical bone defects

NARCIS (Netherlands)

J. van der Stok (Johan); O.P. van der Jagt (Olav); S. Amin Yavari (Saber); M.F.P. de Haas (Mirthe); J.H. Waarsing (Jan); H. Jahr (Holger); E.M.M. van Lieshout (Esther); P. Patka (Peter); J.A.N. Verhaar (Jan); A.A. Zadpoor (Amir Abbas); H.H. Weinans (Harrie)

2013-01-01

textabstractPorous titanium scaffolds have good mechanical properties that make them an interesting bone substitute material for large bone defects. These scaffolds can be produced with selective laser melting, which has the advantage of tailoring the structure's architecture. Reducing the strut

Large scale cluster computing workshop

International Nuclear Information System (INIS)

Dane Skow; Alan Silverman

2002-01-01

Recent revolutions in computer hardware and software technologies have paved the way for the large-scale deployment of clusters of commodity computers to address problems heretofore the domain of tightly coupled SMP processors. Near term projects within High Energy Physics and other computing communities will deploy clusters of scale 1000s of processors and be used by 100s to 1000s of independent users. This will expand the reach in both dimensions by an order of magnitude from the current successful production facilities. The goals of this workshop were: (1) to determine what tools exist which can scale up to the cluster sizes foreseen for the next generation of HENP experiments (several thousand nodes) and by implication to identify areas where some investment of money or effort is likely to be needed. (2) To compare and record experimences gained with such tools. (3) To produce a practical guide to all stages of planning, installing, building and operating a large computing cluster in HENP. (4) To identify and connect groups with similar interest within HENP and the larger clustering community

Resummations in QCD hard-scattering at large and small x

CERN Document Server

Kidonakis, Nikolaos; Stephens, Philip

2008-01-01

We discuss different resummations of large logarithms that arise in hard-scattering cross sections of quarks and gluons in regions of large and small x. The large-x logarithms are typically dominant near threshold for the production of a specified final state. These soft and collinear gluon corrections produce large enhancements of the cross section for many processes, notably top quark and Higgs production, and typically the higher-order corrections reduce the factorization and renormalization scale dependence of the cross section. The small-x logarithms are dominant in the regime where the momentum transfer of the hard sub-process is much smaller than the total collision energy. These logarithms are important to describe multijet final states in deep inelastic scattering and hadron colliders, and in the study of parton distribution functions. The resummations at small and large x are linked by the eikonal approximation and are dominated by soft gluon anomalous dimensions. We will review their role in both c...

Synthesis of pure iron magnetic nanoparticles in large quantity

International Nuclear Information System (INIS)

Tiwary, C S; Kashyap, S; Chattopadhyay, K; Biswas, K

2013-01-01

Free nanoparticles of iron (Fe) and their colloids with high saturation magnetization are in demand for medical and microfluidic applications. However, the oxide layer that forms during processing has made such synthesis a formidable challenge. Lowering the synthesis temperature decreases rate of oxidation and hence provides a new way of producing pure metallic nanoparticles prone to oxidation in bulk amount (large quantity). In this paper we have proposed a methodology that is designed with the knowledge of thermodynamic imperatives of oxidation to obtain almost oxygen-free iron nanoparticles, with or without any organic capping by controlled milling at low temperatures in a specially designed high-energy ball mill with the possibility of bulk production. The particles can be ultrasonicated to produce colloids and can be bio-capped to produce transparent solution. The magnetic properties of these nanoparticles confirm their superiority for possible biomedical and other applications. (paper)

Producing metallurgic coke

Energy Technology Data Exchange (ETDEWEB)

Abe, T.; Isida, K.; Vada, Y.

1982-11-18

A mixture of power producing coals with coal briquets of varying composition is proposed for coking in horizontal chamber furnaces. The briquets are produced from petroleum coke, coal fines or semicoke, which make up less than 27 percent of the mixture to be briquetted and coals with a standard coking output of volatile substances and coals with high maximal Gizeler fluidity. The ratio of these coals in the mixture is 0.6 to 2.1 or 18 to 32 percent, respectively. Noncaking or poorly caking coals are used as the power producing coals. The hardness of the obtained coke is DJ15-30 = 90.5 to 92.7 percent.

Managing flowback and produced water from hydraulic fracturing under stochastic environment

Science.gov (United States)

Zhang, X.; Sun, A. Y.; Duncan, I. J.; Vesselinov, V. V.

2017-12-01

A large volume of wastewater is being generated from hydraulic fracturing in shale gas plays, including flowback and produced water. The produced wastewater in terms of its quantity and quality has become one of the main environmental problems facing shale gas industries worldwide. Cost-effective planning and management of flowback and produced water is highly desirable. Careful choice of treatment, disposal, and reuse options can lower costs and reduce potential environmental impacts. To handle the recourse issue in decision-making, a two-stage stochastic management model is developed to provide optimal alternatives for fracturing wastewater management. The proposed model is capable of prompting corrective actions to allow decision makers to adjust the pre-defined management strategies. By using this two-stage model, potential penalties arising from decision infeasibility can be minimized. The applicability of the proposed model is demonstrated using a representative synthetic example, in which tradeoffs between economic and environmental goals are quantified. This approach can generate informed defensible decisions for shale gas wastewater management. In addition, probabilistic and non-probabilistic uncertainties are effectively addressed.

The Core Interaction of Platforms: How Startups Connect Users and Producers

Directory of Open Access Journals (Sweden)

Heidi M. E. Korhonen

2017-09-01

Full Text Available The platform economy is disrupting innovation while presenting both opportunities and challenges for startups. Platforms support value creation between multiple participant groups, and this operationalization of an ecosystem’s value co-creation represents the “core interaction” of a platform. This article focuses on that core interaction and studies how startups connect producers and users in value-creating core interaction through digital platforms. The study is based on an analysis of 29 cases of platform startups interviewed at a leading European startup event. The studied startups were envisioning even millions of users and hundreds or thousands of producers co-creating value on their platforms. In such platform businesses, our results highlight the importance of attracting a large user pool, providing novel services to those users, offering a new market for producers, supporting the core interaction in various ways, and utilizing elements of the platform canvas – an adaptation of the business model canvas, which we have accommodated for platform-based business models – to accomplish these goals.

Experimental use of produced waters for waterflooding fields of Kuibyshev region

Energy Technology Data Exchange (ETDEWEB)

Palii, P A; Gavura, V E; Redkin, I I; Sokolov, A G

1970-01-01

Large volumes of produced waters have been used for waterflooding in the Kuibyshev region. Before underground injection, the water is conditioned by short-term storage. The treated water contains emulsified oil, suspended solids, hydrogen sulfide, and ferrous iron. This water is readily injected into fractured porous formations, even if suspended solids reach 42 mg/liter and emulsifed oil 67 mg/liter. However, better quality water has to be injected into nonfractured formations. In this case, the concentration of emulsified oil and suspended solids needs to be kept below 5 mg/liter. If concentration of suspended material exceeds this limit, water injectivity decreases rapidly. The partially plugged wells can be restored by acid treatment. Water injection has shown large economic gains in this region.

Large inserts for big data: artificial chromosomes in the genomic era.

Science.gov (United States)

Tocchetti, Arianna; Donadio, Stefano; Sosio, Margherita

2018-05-01

The exponential increase in available microbial genome sequences coupled with predictive bioinformatic tools is underscoring the genetic capacity of bacteria to produce an unexpected large number of specialized bioactive compounds. Since most of the biosynthetic gene clusters (BGCs) present in microbial genomes are cryptic, i.e. not expressed under laboratory conditions, a variety of cloning systems and vectors have been devised to harbor DNA fragments large enough to carry entire BGCs and to allow their transfer in suitable heterologous hosts. This minireview provides an overview of the vectors and approaches that have been developed for cloning large BGCs, and successful examples of heterologous expression.

Operational Aspects of Dealing with the Large BaBar Data Set

Energy Technology Data Exchange (ETDEWEB)

Trunov, Artem G

2003-06-13

To date, the BaBar experiment has stored over 0.7PB of data in an Objectivity/DB database. Approximately half this data-set comprises simulated data of which more than 70% has been produced at more than 20 collaborating institutes outside of SLAC. The operational aspects of managing such a large data set and providing access to the physicists in a timely manner is a challenging and complex problem. We describe the operational aspects of managing such a large distributed data-set as well as importing and exporting data from geographically spread BaBar collaborators. We also describe problems common to dealing with such large datasets.

Impacts of Retailers’ Pricing Strategies for Produce Commodities on Farmer Welfare

OpenAIRE

Li, Chenguang; Sexton, Richard J.

2009-01-01

The typical model of retail pricing for produce products assumes retailers set price equal to the farm price plus a certain markup. However, observations from scanner data indicate a large degree of price dispersion in the grocery retailing market. In addition to markup pricing behavior, we document three alternative leading pricing patterns: fixed (constant) pricing, periodic sale, and high-low pricing. Retail price variations under these alternative pricing regimes in general have little co...

Laser fluorescence on radio-active isotopes produced in very low yield

International Nuclear Information System (INIS)

Dancy, D.E.; Billowes, J.; Grant, I.S.; Evans, D.E.; Griffith, J.A.R.; Wells, S.A.; Eastham, D.A.; Groves, J.; Smith, J.R.H.; Tolfree, D.W.L.; Walker, P.M.

1990-01-01

Fast particle-photon coincidence techniques, developed at Daresbury with strontium isotopes, allow ultra-sensitive laser fluorescence spectroscopy of beams of radio-active isotopes which can only be produced in very low yields. The technique has now been applied to neutron-deficient barium isotopes down to 120 Ba. From measured hyperfine splitting and isotope shifts, nuclear moments and changes in mean square radii have been determined. The work has revealed an abrupt increase in the mean square radius for 121 Ba large enough to disrupt the systematic staggering of nuclear size seen for the series. In a recent experiment an isomeric state of 127 Ba with a half-life of about 2 seconds has been produced in a very low yield; nevertheless we have succeeded in obtaining a fluorescence spectrum. (orig.)

The origin of small and large molecule behavior in the vibrational relaxation of highly excited molecules

International Nuclear Information System (INIS)

Gordon, R.J.

1990-01-01

An explanation is proposed for the qualitatively different types of behavior that have been reported for the vibrational relaxation of highly excited diatomic and polyatomic molecules. It is argued that all of the diatomic molecules that have been studied in bulk relax adiabatically at room temperature. In contrast, large polyatomic molecules have low frequency modes which act at ''doorway'' modes for the rest of the molecules, producing an impulsive relaxation mechanism. The theoretical work of Nesbitt and Hynes showed that impulsive collisions result in an exponential decay of the average vibrational energy of a Morse oscillator, whereas adiabatic collisions produce nonexponential power law behavior. We propose that this result explains a large body of data for the vibrational relaxation of small and large molecules

A survey of images of a phantom produced by radioisotope scanners and cameras

International Nuclear Information System (INIS)

1976-01-01

A working party of the Department of Health and Social Security (DHSS) concerned with the assessment of performance of radioisotope-imaging equipment designed a test pattern called the Williams Phantom. The criteria and design are discussed. It consists of four 'cold' and four 'hot' areas. One Williams Phantom was sent to each radioisotope-imaging centre in Great Britain: the images produced were sent to the DHSS. The variation in image quality was large. A comprehensive sample of the images of the phantom produced on a variety of radioisotope scanners and γ cameras is presented to illustrate a number of general observations made by the working party. (U.K.)

GBT, VLA Team Up to Produce New Image of Orion Nebula

Science.gov (United States)

2002-01-01

Combining the best features of the National Science Foundation's (NSF) new Robert C. Byrd Green Bank Telescope (GBT) in West Virginia with those of the NSF's Very Large Array (VLA) in New Mexico, astronomers have produced a vastly improved radio image of the Orion Nebula and developed a valuable new technique for studying star formation and other astrophysical processes. GBT-VLA Image of Orion Nebula GBT-VLA Image of Orion Nebula "Our GBT image of the Orion Nebula is the best image ever produced with a single-dish radio telescope and it illustrates the superb performance of this new telescope," said Debra Shepherd, of the National Radio Astronomy Observatory (NRAO) in Socorro, NM. "By combining data from the GBT with that from the VLA, we get an image that reflects reality far better than images from the separate telescopes could do," she added. Shepherd worked with Ron Maddalena from NRAO in Green Bank and Joe McMullin, from NRAO in Socorro. The astronomers presented their work to the American Astronomical Society meeting in Washington, DC. Single-dish radio telescopes such as the GBT, dedicated in 2000, are able to capture the large-scale structure of objects such as the Orion Nebula. However, they are unable to discern the fine detail revealed by multi-antenna arrays such as the VLA. Conversely, a VLA-like array is "blind" to the larger-scale structures. Combining the data from both types of radio telescopes to produce an image showing both large- and small-scale structures in the same celestial object has been a difficult, laborious task. "We are developing new observing techniques and software to make this task much easier and quicker," said McMullin. "We now have achieved in hours what used to take months or even longer to do, but we are producing an observational tool that will allow astronomers to make much higher-fidelity images that will greatly improve our understanding of several important astronomical processes," McMullin added. For this observation

Monitoring of large steam turbines, as seen by the constructor and the operator

International Nuclear Information System (INIS)

Blanchet, J.M.; Bourcier, P.B.; Malherbe, C.

1986-01-01

The electricity in France is produced by large steam turbines in the range of 125 000 kW to 1 300 000 kW in nuclear power plants. Some operation problems are encountered on these large machines. The aim of this study is to justify and to describe the monitoring process implemented on the large steam turbines. This short study is divided into three parts: the monitoring justification during the start-up period, one example of a monitoring system, the turbine monitoring during the operation period [fr

Modeling terrestrial gamma ray flashes produced by relativistic feedback discharges

Science.gov (United States)

Liu, Ningyu; Dwyer, Joseph R.

2013-05-01

This paper reports a modeling study of terrestrial gamma ray flashes (TGFs) produced by relativistic feedback discharges. Terrestrial gamma ray flashes are intense energetic radiation originating from the Earth's atmosphere that has been observed by spacecraft. They are produced by bremsstrahlung interactions of energetic electrons, known as runaway electrons, with air atoms. An efficient physical mechanism for producing large fluxes of the runaway electrons to make the TGFs is the relativistic feedback discharge, where seed runaway electrons are generated by positrons and X-rays, products of the discharge itself. Once the relativistic feedback discharge becomes self-sustaining, an exponentially increasing number of relativistic electron avalanches propagate through the same high-field region inside the thundercloud until the electric field is partially discharged by the ionization created by the discharge. The modeling results indicate that the durations of the TGF pulses produced by the relativistic feedback discharge vary from tens of microseconds to several milliseconds, encompassing all durations of the TGFs observed so far. In addition, when a sufficiently large potential difference is available in thunderclouds, a self-propagating discharge known as the relativistic feedback streamer can be formed, which propagates like a conventional positive streamer. For the relativistic feedback streamer, the positive feedback mechanism of runaway electron production by the positrons and X-rays plays a similar role as the photoionization for the conventional positive streamer. The simulation results of the relativistic feedback streamer show that a sequence of TGF pulses with varying durations can be produced by the streamer. The relativistic streamer may initially propagate with a pulsed manner and turn into a continuous propagation mode at a later stage. Milliseconds long TGF pulses can be produced by the feedback streamer during its continuous propagation. However

7 CFR 1206.16 - Producer.

Science.gov (United States)

2010-01-01

... producing, or causing to be produced, mangos beyond the person's own family use and having value at first... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MANGO PROMOTION, RESEARCH, AND INFORMATION Mango Promotion, Research, and Information Order Definitions § 1206.16 Producer. Producer means...

Large-scale enzymatic production of natural flavour esters in organic solvent with continuous water removal.

Science.gov (United States)

Gubicza, L; Kabiri-Badr, A; Keoves, E; Belafi-Bako, K

2001-11-30

A new, large-scale process was developed for the enzymatic production of low molecular weight flavour esters in organic solvent. Solutions for the elimination of substrate and product inhibitions are presented. The excess water produced during the process was continuously removed by hetero-azeotropic distillation and esters were produced at yields of over 90%.

Cryogenics for the Large Hadron Collider

CERN Document Server

Lebrun, P

2000-01-01

The Large Hadron Collider (LHC), a 26.7 km circumference superconducting accelerator equipped with high-field magnets operating in superfluid helium below 1.9 K, has now fully entered construction at CERN, the European Laboratory for Particle Physics. The heart of the LHC cryogenic system is the quasi-isothermal magnet cooling scheme, in which flowing two-phase saturated superfluid helium removes the heat load from the 36000 ton cold mass, immersed in some 400 m/sup 3/ static pressurised superfluid helium. The LHC also makes use of supercritical helium for nonisothermal cooling of the beam screens which intercept most of the dynamic heat loads at higher temperature. Although not used in normal operation, liquid nitrogen will provide the source of refrigeration for precooling the machine. Refrigeration for the LHC is produced in eight large refrigerators, each with an equivalent capacity of about 18 kW at 4.5 K, completed by 1.8 K refrigeration units making use of several stages of hydrodynamic cold compressor...

Large-scale cryopumping for controlled fusion

International Nuclear Information System (INIS)

Pittenger, L.C.

1977-01-01

Vacuum pumping by freezing out or otherwise immobilizing the pumped gas is an old concept. In several plasma physics experiments for controlled fusion research, cryopumping has been used to provide clean, ultrahigh vacua. Present day fusion research devices, which rely almost universally upon neutral beams for heating, are high gas throughput systems, the pumping of which is best accomplished by cryopumping in the high mass-flow, moderate-to-high vacuum regime. Cryopumping systems have been developed for neutral beam injection systems on several fusion experiments (HVTS, TFTR) and are being developed for the overall pumping of a large, high-throughput mirror containment experiment (MFTF). In operation, these large cryopumps will require periodic defrosting, some schemes for which are discussed, along with other operational considerations. The development of cryopumps for fusion reactors is begun with the TFTR and MFTF systems. Likely paths for necessary further development for power-producing reactors are also discussed

Large-scale cryopumping for controlled fusion

Energy Technology Data Exchange (ETDEWEB)

Pittenger, L.C.

1977-07-25

Vacuum pumping by freezing out or otherwise immobilizing the pumped gas is an old concept. In several plasma physics experiments for controlled fusion research, cryopumping has been used to provide clean, ultrahigh vacua. Present day fusion research devices, which rely almost universally upon neutral beams for heating, are high gas throughput systems, the pumping of which is best accomplished by cryopumping in the high mass-flow, moderate-to-high vacuum regime. Cryopumping systems have been developed for neutral beam injection systems on several fusion experiments (HVTS, TFTR) and are being developed for the overall pumping of a large, high-throughput mirror containment experiment (MFTF). In operation, these large cryopumps will require periodic defrosting, some schemes for which are discussed, along with other operational considerations. The development of cryopumps for fusion reactors is begun with the TFTR and MFTF systems. Likely paths for necessary further development for power-producing reactors are also discussed.

Highly uniform parallel microfabrication using a large numerical aperture system

Energy Technology Data Exchange (ETDEWEB)

Zhang, Zi-Yu; Su, Ya-Hui, E-mail: ustcsyh@ahu.edu.cn, E-mail: dongwu@ustc.edu.cn [School of Electrical Engineering and Automation, Anhui University, Hefei 230601 (China); Zhang, Chen-Chu; Hu, Yan-Lei; Wang, Chao-Wei; Li, Jia-Wen; Chu, Jia-Ru; Wu, Dong, E-mail: ustcsyh@ahu.edu.cn, E-mail: dongwu@ustc.edu.cn [CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei 230026 (China)

2016-07-11

In this letter, we report an improved algorithm to produce accurate phase patterns for generating highly uniform diffraction-limited multifocal arrays in a large numerical aperture objective system. It is shown that based on the original diffraction integral, the uniformity of the diffraction-limited focal arrays can be improved from ∼75% to >97%, owing to the critical consideration of the aperture function and apodization effect associated with a large numerical aperture objective. The experimental results, e.g., 3 × 3 arrays of square and triangle, seven microlens arrays with high uniformity, further verify the advantage of the improved algorithm. This algorithm enables the laser parallel processing technology to realize uniform microstructures and functional devices in the microfabrication system with a large numerical aperture objective.

[Isolation and identification of a lactate-utilizing, butyrate-producing bacterium and its primary metabolic characteristics].

Science.gov (United States)

Liu, Wei; Zhu, Wei-yun; Yao, Wen; Mao, Sheng-yong

2007-06-01

The distal mammalian gut harbors prodigiously abundant microbes, which provide unique metabolic traits to host. A lactate-utilizing, butyrate-producing bacterium, strain LB01, was isolated from adult swine feces by utilizing modified Hungate technique with rumen liquid-independent YCFA medium supplemented with lactate as the single carbon source. It was an obligate anaerobic, Gram positive bacterium, and could utilize glucose, fructose, maltose and lactate with a large amount of gas products. 16S rRNA sequence analysis revealed that it had the high similarity with members of the genus Megasphaera. The metabolic characteristics of strain LB01 was investigated by using in vitro fermentation system. Lactate at the concentration of 65 mmol/L in YCFA medium was rapidly consumed within 9 hours and was mainly converted to propionate and butyrate after 24h. As the level of acetate declined, the concentration of butyrate rose only in the presence of glucose, suggesting that butyrate could possibly be synthesized by the acetyl CoA: butyryl CoA transferase. When co-cultured with lactic acid bacteria strain K9, strain LB01 evidently reduced the concentration of lactate produced by strain K9 and decelerated the rapid pH drop, finally producing 12.11 mmol/L butyrate and 4.06 mmol/L propionate. The metabolic characteristics that strain LB01 efficiently converts toxic lactate and excessive acetate to butyrate can prevent lactate and acetate accumulation in the large intestine and maintain the slightly acidic environment of the large intestine, consequently revealing that stain LB01 could act as a potential probiotics.

Cavities produced by underground nuclear explosions

International Nuclear Information System (INIS)

Butkovich, T.R.

1976-01-01

This investigation studied the displacement of rock that formerly occupied cavities produced by underground nuclear explosions. There are three possible explanations for this displacement: the volume could be displaced to the free surface; it could occupy previously air-filled pores removed from the surrounding rock through compaction; or it could be accounted for by persisting compressive stresses induced by the outgoing shock wave. The analysis shows it unlikely that stored residual elastic stresses account for large fractions of cavity volumes. There is limited experimental evidence that free surface displacement accounts for a significant portion of this volume. Whenever the explosion mediums contain air-filled pores, the compaction of these pores most likely accounts for all the volume. Calculations show that 4 percent air-filled porosity can account for all the cavity volume within about 4 cavity radii and that even 1 percent can account for a significant fraction of the volume

Non-Invasive Rapid Harvest Time Determination of Oil-Producing Microalgae Cultivations for Biodiesel Production by Using Chlorophyll Fluorescence

Energy Technology Data Exchange (ETDEWEB)

Qiao, Yaqin [Key Laboratory of Algal Biology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan (China); University of Chinese Academy of Sciences, Beijing (China); Rong, Junfeng [SINOPEC Research Institute of Petroleum Processing, Beijing (China); Chen, Hui; He, Chenliu; Wang, Qiang, E-mail: wangqiang@ihb.ac.cn [Key Laboratory of Algal Biology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan (China)

2015-10-05

For the large-scale cultivation of microalgae for biodiesel production, one of the key problems is the determination of the optimum time for algal harvest when algae cells are saturated with neutral lipids. In this study, a method to determine the optimum harvest time in oil-producing microalgal cultivations by measuring the maximum photochemical efficiency of photosystem II, also called Fv/Fm, was established. When oil-producing Chlorella strains were cultivated and then treated with nitrogen starvation, it not only stimulated neutral lipid accumulation, but also affected the photosynthesis system, with the neutral lipid contents in all four algae strains – Chlorella sorokiniana C1, Chlorella sp. C2, C. sorokiniana C3, and C. sorokiniana C7 – correlating negatively with the Fv/Fm values. Thus, for the given oil-producing algae, in which a significant relationship between the neutral lipid content and Fv/Fm value under nutrient stress can be established, the optimum harvest time can be determined by measuring the value of Fv/Fm. It is hoped that this method can provide an efficient way to determine the harvest time rapidly and expediently in large-scale oil-producing microalgae cultivations for biodiesel production.

Plastic flow produced by single ion impacts on metals

International Nuclear Information System (INIS)

Birtcher, R. C.

1998-01-01

Single ion impacts have been observed using in situ transmission electron microscopy and video recording with a time resolution of 33 milliseconds. Gold was irradiated at 50 K and room temperature. Single ion impacts produce holes, modify existing holes, and extrude material into the initial specimen hole and holes formed by other ion impacts. The same behavior is observed at both temperatures. At both temperatures, ion impacts result in craters and ejected material. Ion impacts produce more small craters than large ones for all ion masses, while heavier mass ions produce more and larger craters than lighter mass ions. This comparison is affected by the ion energy. As the energy of an ion is increased, the probability for deposition near the surface decreases and fewer craters are formed. For a given ion mass, crater production depends on the probability for displacement cascade production in the near surface region. Crater and holes are stable at room temperature, however, ion impacts near an existing crater may cause flow of material into the crater either reshaping or annihilating it. Holes and craters result from the explosive outflow of material from the molten zone of near-surface cascades. The outflow may take the form of molten material, a solid lid or an ejected particle. The surface is a major perturbation on displacement cascades resulting from ion impacts

Large dose hyperpolarized water with dissolution-DNP at high magnetic field

DEFF Research Database (Denmark)

Lipsø, Hans Kasper Wigh; Bowen, Sean; Rybalko, Oleksandr

2016-01-01

was polarized and dissolved in a fluid path compatible with clinical polarizers. The volume of hyperpolarized water produced by this method enables angiography and perfusion measurements in large animals, as well as NMR experiments for studies of e.g. proton exchange and polarization transfer to other nuclei....

Bioavailability of isoflavones from soy products in equol producers and non-producers in Japanese women

Directory of Open Access Journals (Sweden)

Ayako Miura

2016-12-01

Conclusions: The results in this study suggest that bioavailability of isoflavones are different between equol producers and non-producers, because the 24 h urinary excretion of equol in the equol producers were significantly lower than those in the equol non-producers.

Yeast: A new oil producer?

Directory of Open Access Journals (Sweden)

Beopoulos Athanasios

2012-01-01

Full Text Available The increasing demand of plant oils or animal fat for biodiesel and specific lipid derivatives for the oleochemical field (such as lubricants, adhesives or plastics have created price imbalance in both the alimentary and energy field. Moreover, the lack of non-edible oil feedstock has given rise to concerns on land-use practices and on oil production strategies. Recently, much attention has been paid to the exploitation of microbial oils. Most of them present lipid profiles similar in type and composition to plants and could therefore have many advantages as are no competitive with food, have short process cycles and their cultivation is independent of climate factors. Among microorganisms, yeasts seem to be very promising as they can be easily genetically enhanced, are suitable for large-scale fermentation and are devoid of endotoxins. This review will focus on the recent understanding of yeasts lipid metabolism, the succeeding genetic engineering of the lipid pathways and the recent developments on fermentation techniques that pointed out yeasts as promising alternative producers for oil or plastic.

Large-signal, dynamic simulation of the slowpoke-3 nuclear heating reactor

International Nuclear Information System (INIS)

Tseng, C.M.; Lepp, R.M.

1983-07-01

A 2 MWt nuclear reactor, called SLOWPOKE-3, is being developed at the Chalk River Nuclear Laboratories (CRNL). This reactor, which is cooled by natural circulation, is designed to produce hot water for commercial space heating and perhaps generate some electricity in remote locations where the costs of alternate forms of energy are high. A large-signal, dynamic simulation of this reactor, without closed-loop control, was developed and implemented on a hybrid computer, using the basic equations of conservation of mass, energy and momentum. The natural circulation of downcomer flow in the pool was simulated using a special filter, capable of modelling various flow conditions. The simulation was then used to study the intermediate and long-term transient response of SLOWPOKE-3 to large disturbances, such as loss of heat sink, loss of regulation, daily load following, and overcooling of the reactor coolant. Results of the simulation show that none of these disturbances produce hazardous transients

Literature in focus - The Large Hadron Collider: A Marvel of Technology

CERN Document Server

Cecile Noels

Inside an insulating vacuum chamber in a tunnel about 100 metres below the surface of the Franco-Swiss plain near Geneva, packets of protons whirl around the 27-km circumference of the Large Hadron Collider (LHC) at a speed close to that of light, colliding every 25 nanoseconds at four beam crossing points. The products of these collisions, of which hundreds of billions will be produced each second, are observed and measured with the most advanced particle-detection technology, capable of tracking individual particles as they generate a signature track during their passage through the detectors. All this information is captured, filtered and piped to huge networks of microprocessors for analysis and study by an international team of physicists. When the Large Hadron Collider (LHC) comes on line in 2009, it will be the largest scientific experiment ever constructed, and the data it produces will lead to a new understanding of our Universe. Many thousands of scientists and engineers were behind the planning...

Literature in focus - The Large Hadron Collider: A Marvel of Technology

CERN Document Server

Cecile Noels

2009-01-01

Inside an insulating vacuum chamber in a tunnel about 100 metres below the surface of the Franco-Swiss plain near Geneva, packets of protons whirl around the 27-km circumference of the Large Hadron Collider (LHC) at a speed close to that of light, colliding every 25 nanoseconds at four beam crossing points. The products of these collisions, of which hundreds of billions will be produced each second, are observed and measured with the most advanced particle-detection technology, capable of tracking individual particles as they generate a signature track during their passage through the detectors. All this information is captured, filtered and piped to huge networks of microprocessors for analysis and study by an international team of physicists. When the Large Hadron Collider (LHC) comes on line in 2009, it will be the largest scientific experiment ever constructed, and the data it produces will lead to a new understanding of our Universe. Many thousands of scientists and engineers were behind the planning...

Large Scale Generation and Characterization of Anti-Human CD34 Monoclonal Antibody in Ascetic Fluid of Balb/c Mice

OpenAIRE

Aghebati Maleki, Leili; Majidi, Jafar; Baradaran, Behzad; Abdolalizadeh, Jalal; Kazemi, Tohid; Aghebati Maleki, Ali; Sineh sepehr, Koushan

2013-01-01

Purpose: Monoclonal antibodies or specific antibodies are now an essential tool of biomedical research and are of great commercial and medical value. The purpose of this study was to produce large scale of monoclonal antibody against CD34 in order to diagnostic application in leukemia and purification of human hematopoietic stem/progenitor cells. Methods: For large scale production of monoclonal antibody, hybridoma cells that produce monoclonal antibody against human CD34 were injected into t...

Large aspect ratio tokamak study

International Nuclear Information System (INIS)

Reid, R.L.; Holmes, J.A.; Houlberg, W.A.; Peng, Y.K.M.; Strickler, D.J.; Brown, T.G.; Sardella, C.; Wiseman, G.W.

1979-01-01

The Large Aspect Ratio Tokamak Study (LARTS) investigated the potential for producing a viable long burn tokamak reactor through enhanced volt-second capability of the ohmic heating transformer by employing high aspect ratio designs. The plasma physics, engineering, and economic implications of high aspect ratio tokamaks were accessed in the context of extended burn operation. Plasma startup and burn parameters were addressed using a one-dimensional transport code. The pulsed electrical power requirements for the poloidal field system, which have a major impact on reactor economics, were minimized by optimizing the field in the ohmic heating coil and the wave shape of the ohmic heating discharge. A high aspect ratio reference reactor was chosen and configured

The regulation of function, growth and survival of GLP-1-producing L-cells

DEFF Research Database (Denmark)

Kuhre, Rune Ehrenreich; Holst, Jens Juul; Kappe, Camilla

2016-01-01

that regulate the growth, survival and function of these cells are largely unknown. We recently showed that prolonged exposure to high concentrations of the fatty acid palmitate induced lipotoxic effects, similar to those operative in insulin-producing cells, in an in vitro model of GLP-1-producing cells...... absorption and disposal, as well as cell proliferation and survival. In Type 2 Diabetes (T2D) reduced plasma levels of GLP-1 have been observed, and plasma levels of GLP-1, as well as reduced numbers of GLP-1 producing cells, have been correlated to obesity and insulin resistance. Increasing endogenous...... secretion of GLP-1 by selective targeting of the molecular mechanisms regulating secretion from the L-cell has been the focus of much recent research. An additional and promising strategy for enhancing endogenous secretion may be to increase the L-cell mass in the intestinal epithelium, but the mechanisms...

Unexpected levels and movement of radon in a large warehouse

International Nuclear Information System (INIS)

Gammage, R.B.; Espinosa, G.

2004-01-01

Alpha-track detectors, used in screening for radon, identified a large warehouse with levels of radon as high as 20 p Ci/l. This circumstance was unexpected because large bay doors were left open for much of the day to admit 1 8-wheeler trucks, and exhaust fans in the roof produced good ventilation. More detailed temporal and spatial investigations of radon and air-flow patterns were made with electret chambers, Lucas-cell flow chambers, tracer gas, smoke pencils and pressure sensing micrometers. An oval-dome shaped zone of radon (>4 p Ci/L) persisted in the central region of each of four separate bays composing the warehouse. Detailed studies of air movement in the bay with the highest levels of radon showed clockwise rotation of air near the outer walls with a central dead zone. Sub slab, radon-laden air ingresses the building through expansion joints between the floor slabs to produce the measured radon. The likely source of radon is air within porous, karst bedrock that underlies much of north-central Tennessee where the warehouse is situated

POLICY ANALYSIS OF PRODUCED WATER ISSUES ASSOCIATED WITH IN-SITU THERMAL TECHNOLOGIES

Energy Technology Data Exchange (ETDEWEB)

Robert Keiter; John Ruple; Heather Tanana

2011-02-01

Commercial scale oil shale and oil sands development will require water, the amount of which will depend on the technologies adopted and the scale of development that occurs. Water in oil shale and oil sands country is already in scarce supply, and because of the arid nature of the region and limitations on water consumption imposed by interstate compacts and the Endangered Species Act, the State of Utah normally does not issue new water rights in oil shale or oil sands rich areas. Prospective oil shale and oil sands developers that do not already hold adequate water rights can acquire water rights from willing sellers, but large and secure water supplies may be difficult and expensive to acquire, driving oil shale and oil sands developers to seek alternative sources of supply. Produced water is one such potential source of supply. When oil and gas are developed, operators often encounter ground water that must be removed and disposed of to facilitate hydrocarbon extraction. Water produced through mineral extraction was traditionally poor in quality and treated as a waste product rather than a valuable resource. However, the increase in produced water volume and the often-higher quality water associated with coalbed methane development have drawn attention to potential uses of produced water and its treatment under appropriations law. This growing interest in produced water has led to litigation and statutory changes that must be understood and evaluated if produced water is to be harnessed in the oil shale and oil sands development process. Conversely, if water is generated as a byproduct of oil shale and oil sands production, consideration must be given to how this water will be disposed of or utilized in the shale oil production process. This report explores the role produced water could play in commercial oil shale and oil sands production, explaining the evolving regulatory framework associated with produced water, Utah water law and produced water regulation

Organic and inorganic species in produced water: Implications for water reuse

Science.gov (United States)

Kharaka, Yousif K.; Rice, Cynthia A.

2004-01-01

Currently 20-30 billion barrels of formation water are co-produced annually in the USA with conventional oil and natural gas. The large database on the geochemistry of this produced water shows salinities that vary widely from ~5,000 to >350,000 mg/L TDS. Chloride, Na and Ca are generally the dominant ions, and concentrations of Fe, Mn, B, NH3 and dissolved organics, including, BTEX, phenols and poly aromatic hydrocarbons (PAHs) may be relatively high. Hazardous concentrations of NORMs, including Ra-226 and Rn-222 have been reported in produced water from several states.Coal-bed methane (CBM) wells currently produce close to a billion barrels of water and deliver ~8% of total natural gas. The salinity of this produced water generally is lower than that of water from petroleum wells; salinity commonly is 1,000-20,000 mg/L, but ranges to150,000 mg/L TDS. Most CBM wells produce Na-HCO3-Cl type water that is low in trace metals and has no reported NORMs. This water commonly has no oil and grease and has relatively low DOC, but its organic composition has not been characterized in detail. The water is disposed of by injection into saline aquifers, through evaporation and/or percolation in disposal pits, road spreading, and surface discharge. Water that has an acceptable salinity and sodium absorption ratio (SAR) is considered acceptable for surface discharge and for injection into freshwater aquifers.As an alternative to costly disposal, low salinity produced water is being considered for reclamation, especially in the arid western USA. The cost of reclaiming this water to meet irrigation, industrial and drinking water standards was evaluated in a 10 gpm pilot field study at Placerita oil field, California. This produced water had a low salinity of ~8,000 mg/L, but high concentration of Si and organics. Removal of B, Si, NH3 and especially organics from this water proved difficult, and the estimated treatment cost was high at $0.08-$0.39/bbl for water treated for

Bio-based production of fuels and industrial chemicals by repurposing antibiotic-producing type I modular polyketide synthases: opportunities and challenges

DEFF Research Database (Denmark)

Yuzawa, Satoshi; Keasling, Jay D.; Katz, Leonard

2017-01-01

Complex polyketides comprise a large number of natural products that have broad application in medicine and agriculture. They are produced in bacteria and fungi from large enzyme complexes named type I modular polyketide synthases (PKSs) that are composed of multifunctional polypeptides containin...... have applications as fuels or industrial chemicals....

Brookhaven Linac Isotope Producer

Data.gov (United States)

Federal Laboratory Consortium — The Brookhaven Linac Isoptope Producer (BLIP)—positioned at the forefront of research into radioisotopes used in cancer treatment and diagnosis—produces commercially...

Factors Influencing Demand for a Producer-Owned Beef Retail Outlet

OpenAIRE

Lusk, Jayson L.; Cevallos, Edgar

2004-01-01

As the farm-to-retail price spread continues to grow, come cattle producers a beginning to consider integrating into the retail sector. Such a venture would require large investments in capital with uncertain return. This study seeks to determine the potential success of a stand-alone retail outlet selling “all natural†beef in an affluent area of Jackson, MS. Using choice-based conjoint analysis, demand for the new retail outlet is modeled as a function of the beef price at the store, dis...

Importance in dairy technology of bacteriocins produced by dairy starter cultures

Directory of Open Access Journals (Sweden)

Bedia Şimşek

2002-03-01

Full Text Available Bacteriocins produced by Lactic acid bacteria (LAB and propionic acid bacteria (PAB are heterogeneous group of peptide inhibitors which include lantibiotics (class I, e. g. nisin, small heat-stable peptides (class II, e. g. pediocin PA-1 and large heat-labile proteins (class III, e. g. helveticin J. Many bacteriocins belonging to the first two groups can be successfully used to inhibit undesirable microorganisms in foods, but only nisin is produced industrially and is used as a food preservative. LAB and PAB develops easily in milk and milk products. LAB and PAB growth in dairy products can cause microbial interference to spoilage and pathogenic bacteria through several metabolits, specially bacteriocins. The review deals with the description of milk-borne bacteriocins and their application in milk and milk products either to extend the shelf life or to inhibit milk pathogens.

Lightning characteristics of derecho producing mesoscale convective systems

Science.gov (United States)

Bentley, Mace L.; Franks, John R.; Suranovic, Katelyn R.; Barbachem, Brent; Cannon, Declan; Cooper, Stonie R.

2016-06-01

Derechos, or widespread, convectively induced wind storms, are a common warm season phenomenon in the Central and Eastern United States. These damaging and severe weather events are known to sweep quickly across large spatial regions of more than 400 km and produce wind speeds exceeding 121 km h-1. Although extensive research concerning derechos and their parent mesoscale convective systems already exists, there have been few investigations of the spatial and temporal distribution of associated cloud-to-ground lightning with these events. This study analyzes twenty warm season (May through August) derecho events between 2003 and 2013 in an effort to discern their lightning characteristics. Data used in the study included cloud-to-ground flash data derived from the National Lightning Detection Network, WSR-88D imagery from the University Corporation for Atmospheric Research, and damaging wind report data obtained from the Storm Prediction Center. A spatial and temporal analysis was conducted by incorporating these data into a geographic information system to determine the distribution and lightning characteristics of the environments of derecho producing mesoscale convective systems. Primary foci of this research include: (1) finding the approximate size of the lightning activity region for individual and combined event(s); (2) determining the intensity of each event by examining the density and polarity of lightning flashes; (3) locating areas of highest lightning flash density; and (4) to provide a lightning spatial analysis that outlines the temporal and spatial distribution of flash activity for particularly strong derecho producing thunderstorm episodes.

Mortar modified with sulfonated polystyrene produced from waste plastic cups

Directory of Open Access Journals (Sweden)

L. A. C. MOTTA

Full Text Available Abstract In this work, we studied the addition of sulfonated polystyrene produced from waste plastic cups as an admixture for mortars. Mortars were analyzed with polystyrene content of 0.0; 0.2; 0.6; 1.0 and 1.4% in relation to the cement mass. The influence of polystyrene on the mortars' properties was evaluated by the consistency index, water retention, water absorption, porosity, elasticity modulus, compressive strength, flexural strength, bond tensile strength and microscopy. The increase in the sulfonated polystyrene content decreased the elasticity modulus of the mortar and, despite higher porosity, there was a reduction of water absorption by capillarity. In relation to mortar without admixture, the modified mortar showed an increase in water retention and consistency index, and a large increase in flexural strength and bond tensile strength. The significant increase of bond tensile strength (214% with admixture 1% highlights the potential of the produced material as an adhesive mortar.

Large scale integration of photovoltaics in cities

International Nuclear Information System (INIS)

Strzalka, Aneta; Alam, Nazmul; Duminil, Eric; Coors, Volker; Eicker, Ursula

2012-01-01

Highlights: ► We implement the photovoltaics on a large scale. ► We use three-dimensional modelling for accurate photovoltaic simulations. ► We consider the shadowing effect in the photovoltaic simulation. ► We validate the simulated results using detailed hourly measured data. - Abstract: For a large scale implementation of photovoltaics (PV) in the urban environment, building integration is a major issue. This includes installations on roof or facade surfaces with orientations that are not ideal for maximum energy production. To evaluate the performance of PV systems in urban settings and compare it with the building user’s electricity consumption, three-dimensional geometry modelling was combined with photovoltaic system simulations. As an example, the modern residential district of Scharnhauser Park (SHP) near Stuttgart/Germany was used to calculate the potential of photovoltaic energy and to evaluate the local own consumption of the energy produced. For most buildings of the district only annual electrical consumption data was available and only selected buildings have electronic metering equipment. The available roof area for one of these multi-family case study buildings was used for a detailed hourly simulation of the PV power production, which was then compared to the hourly measured electricity consumption. The results were extrapolated to all buildings of the analyzed area by normalizing them to the annual consumption data. The PV systems can produce 35% of the quarter’s total electricity consumption and half of this generated electricity is directly used within the buildings.

Experimental Study of the Phenomenology of Spallation Neutrons in a Large Lead Block

CERN Multimedia

Galvez Altamirano, J; Lopez, C; Perlado, J M; Perez-Navarro, A

2002-01-01

%PS211 %title \\\\ \\\\The purpose of PS211 is to determine how neutrons, produced by spallation inside a large Lead volume are slowed down by undergoing a very large number of scatterings, losing each time a small fraction ($\\sim$ 1\\%) of their kinetic energy. The focus is in determining the probability for a spallation neutron produced at an energy of several MeV or more, to survive capture on Lead resonances and to reach resonance energies of materials to be transmuted, such as 5.6 eV for $^{99}$Tc. This process, of Adiabatic Resonance Crossing, involves a subtle interplay between the capture resonances of the Lead medium and of selected impurities. This phenomenology of spallation neutrons in a large Lead volume, is the physics foundation of the Fast Energy Amplifier proposed by C. Rubbia, and could open up new possibilities in the incineration of long-lived nuclear waste such as Actinides or Fission Fragments (e.g. $^{99}$Tc, $^{129}$I, etc.).\\\\ \\\\334 tons of high purity Lead, installed in t7, are exposed to...

Search for large extra dimensions in the exclusive photon + missing energy channel in p$\\bar{p}$ collisions

Energy Technology Data Exchange (ETDEWEB)

Lazoflores, Jose A. [Florida State Univ., Tallahassee, FL (United States)

2006-01-01

A search was conducted for evidence of large extra dimensions (LED) at Fermi National Accelerator Laboratory's Tevatron using the D0 detector. The Tevatron is a p$\\bar{p}$ collider at a center of mass energy of 1.96 TeV. Events with particles escaping into extra dimensions will have large missing energy. The search was carried out using data from a total luminosity of 197 ± 13 pb^-1 with an observable high transverse momentum photon and a large transverse missing energy. The 70 observed events are consistent with photons produced by standard known reactions plus other background processes produced by cosmic muons. The mass limits on the fundamental mass scale at 95% confidence level for large extra dimensions of 2, 4, 6 and 8 are 500 GeV, 581 GeV, 630 GeV, and 668 GeV respectively.

Higher-Twist Dynamics in Large Transverse Momentum Hadron Production

International Nuclear Information System (INIS)

Francois, Alero

2009-01-01

A scaling law analysis of the world data on inclusive large-p # perpendicular# hadron production in hadronic collisions is carried out. A significant deviation from leading-twist perturbative QCD predictions at next-to-leading order is reported. The observed discrepancy is largest at high values of x # perpendicular# = 2p # perpendicular#/√s. In contrast, the production of prompt photons and jets exhibits the scaling behavior which is close to the conformal limit, in agreement with the leading-twist expectation. These results bring evidence for a non-negligible contribution of higher-twist processes in large-p # perpendicular# hadron production in hadronic collisions, where the hadron is produced directly in the hard subprocess rather than by gluon or quark jet fragmentation. Predictions for scaling exponents at RHIC and LHC are given, and it is suggested to trigger the isolated large-p # perpendicular# hadron production to enhance higher-twist processes.

Process for producing a polymer

Energy Technology Data Exchange (ETDEWEB)

Koshimura, M; Haruta, K; Matsuzaka, J; Terakado, H

1969-02-13

A novel polymer is produced by a novel polymerization or copolymerization process in the presence of a free radical-forming catalyst or radical-forming irradiation energy to provide a monomer of the general formula CH/sub 2/=C(R/sub 1/)(COO)-(R/sub 2/OOCR/sub 3/COO)sub(n)-R/sub 2/OH wherein R/sub 1/ is hydrogen, halogen or alkyl radical containing one or two atoms; R/sub 2/ is an epoxy compound residue; R/sub 3/ is a polybasic anhydride residue; and n is an integer. This polymer: (1) enables the cross-linking reaction, (2) improves the adhesiveness of adhesives, pigments, films and coatings; (3) is adjustable for mutual solubility and affinity when blending with other solvents and resins; (4) is resistant to yellowing and mechanically stronger than the benzene nucleus of styrene; (5) improves the textile dyeing affinity, adhesiveness and dispersion of pigments, and the dimensional stability of films and sheets; (6) is suitable as a molding material of synthetic resins, adhesives and coatings because of its three dimensional cross-linking construction; (7) can control the hardness, flexibility and rigidity of the molding materials; and (8) can lower the cost of production. In an example, 10 g of the monomer of the above mentioned formula wherein n=1, R/sub 1/=CH/sub 3/, R/sub 2/=-(CH/sub 2/)/sub 2/ and R/sub 3/ is ortho-substituted benzene, and 0.1 g of benzol peroxide, are added to ampoule, sealed and polymerized at 120/sup 0/C for 2 hours. Next the contents are precipitated in a large amount of benzene to produce a polymer having a molecular weight of 9,500. The products have good dimensional stability as molding materials.

MODIL cryocooler producibility demonstration project results

International Nuclear Information System (INIS)

Cruz, G.E.; Franks, R.M.

1993-01-01

The production of large quantities of spacecraft needed by SDIO will require a cultural change in design and production practices. Low rates production and the need for exceedingly high reliability has driven the industry to custom designed, hand crafted, and exhaustively tested satellites. These factors have mitigated against employing design and manufacturing cost reduction methods commonly used in tactical missile production. Additional challenges to achieving production efficiencies are presented by the SDI spacecraft mission requirement. IR sensor systems, for example, are comprised of subassemblies and components that require the design, manufacture, and maintenance of ultra precision tolerances over challenging operational lifetimes. These IR sensors demand the use of reliable, closed loop, cryogenic refrigerators or active cryocoolers to meet stringent system acquisition and pointing requirements. The authors summarize some spacecraft cryocooler requirements and discuss observations regarding Industry's current production capabilities of cryocoolers. The results of the Lawrence Livermore National Laboratory (LLNL) Spacecraft Fabrication and Test (SF and T) MODIL's Phase I producibility demonstration project is presented

Concerted suppression of all starch branching enzyme genes in barley produces amylose-only starch granules

DEFF Research Database (Denmark)

Carciofi, Massimiliano; Blennow, Andreas; Jensen, Susanne L

2012-01-01

to glucose and rapidly absorbed in the small intestine. But a portion of dietary starch, termed "resistant starch" (RS) escapes digestion and reaches the large intestine, where it is fermented by colonic bacteria producing short chain fatty acids (SCFA) which are linked to several health benefits. The RS...

Transverse-momentum distribution of produced particles in ultrarelativistic nucleus-nucleus collisions

International Nuclear Information System (INIS)

Ban-Hao, S.; Wong, C.

1985-01-01

In order to discern coherent or collective processes from incoherent processes in nucleus-nucleus reactions at high energies, we study the transverse-momentum distribution of the produced particles with an incoherent-multiple-collision model. In this model, the projectile nucleon makes successive inelastic collisions with nucleons in the target nucleus, the probability of such collisions being given by the thickness function and the nucleon-nucleon inelastic cross section. It is assumed that each baryon-baryon collision produces particles and degrades momenta just as a baryon-baryon collision in free space, and that there are no secondary collisions between the produced particles and the nucleons. We found that the average transverse momentum and the charged-multiplicity data at Fermilab and CERN ISR energies can be well explained by such a model. However, the average transverse momentum for some events observed by the Japanese-American cooperative emulsion experiment (JACEE) associated with large energy density in the central rapidity region differ markedly from the model results. Such a deviation indicates the presence of coherent or collective effects for these collisions and may indicate the possibility of a formation of quark-gluon plasma

Analysis of Large-Strain Extrusion Machining with Different Chip Compression Ratios

Directory of Open Access Journals (Sweden)

Wen Jun Deng

2012-01-01

Full Text Available Large-Strain Extrusion Machining (LSEM is a novel-introduced process for deforming materials to very high plastic strains to produce ultra-fine nanostructured materials. Before the technique can be exploited, it is important to understand the deformation behavior of the workpiece and its relationship to the machining parameters and friction conditions. This paper reports finite-element method (FEM analysis of the LSEM process to understand the evolution of temperature field, effective strain, and strain rate under different chip compression ratios. The cutting and thrust forces are also analyzed with respect to time. The results show that LSEM can produce very high strains by changing in the value of chip compression ratio, thereby enabling the production of nanostructured materials. The shape of the chip produced by LSEM can also be geometrically well constrained.

Innovating a system for producing and distributing hybrid oil palm seedlings to smallholder farmers in Benin

NARCIS (Netherlands)

Vissoh, Pierre V.; Tossou, Rigobert C.; Akpo, Essegbemon; Kossou, Dansou; Jiggins, Janice

2017-01-01

This article analyses the development of a system for producing and distributing hybrid oil palm seedlings to small-scale famers. The existing seed system had become so corrupted that the seedlings actually planted were largely of unimproved kinds. The article describes institutional experiments

Production of a large diameter ECR plasma with low electron temperature

International Nuclear Information System (INIS)

Koga, Mayuko; Hishikawa, Yasuhiro; Tsuchiya, Hayato; Kawai, Yoshinobu

2006-01-01

A large diameter plasma over 300 mm in diameter is produced by electron cyclotron resonance (ECR) discharges using a cylindrical vacuum chamber of 400 mm in inner diameter. It is found that the plasma uniformity is improved by adding the nitrogen gas to pure Ar plasma. The electron temperature is decreased by adding the nitrogen gas. It is considered that the electron energy is absorbed in the vibrational energy of nitrogen molecules and the electron temperature decreases. Therefore, the adjunction of the nitrogen gas is considered to be effective for producing uniform and low electron temperature plasma

Confinement characteristics of high-energy ions produced by ICRF heating in the large helical device

International Nuclear Information System (INIS)

Kumazawa, R; Saito, K; Torii, Y; Mutoh, T; Seki, T; Watari, T; Osakabe, M; Murakami, S; Sasao, M; Watanabe, T; Yamamoto, T; Notake, T; Takeuchi, N; Saida, T; Shimpo, F; Nomura, G; Yokota, M; Kato, A; Zao, Y; Okada, H; Isobe, M; Ozaki, T; Narihara, K; Nagayama, Y; Inagaki, S; Morita, S; Krasilnikov, A V; Idei, H; Kubo, S; Ohkubo, K; Sato, M; Shimozuma, T; Yoshimura, Y; Ikeda, K; Nagaoka, K; Oka, Y; Takeiri, Y; Tsumori, K; Ashikawa, N; Emoto, M; Funaba, H; Goto, M; Ida, K; Kobuchi, T; Liang, Y; Masuzaki, S; Minami, T; Miyazawa, J; Morisaki, T; Muto, S; Nakamura, Y; Nakanishi, H; Nishimura, K; Noda, N; Ohdachi, S; Peterson, B J; Sagara, A; Sakakibara, S; Sakamoto, R; Sato, K; Shoji, M; Suzuki, H; Tanaka, K; Toi, K; Tokuzawa, T; Watanabe, K Y; Yamada, I; Yamamoto, S; Yoshinuma, M; Yokoyama, M; Watanabe, K-Y; Kaneko, O; Kawahata, K; Komori, A; Ohyabu, N; Yamada, H; Yamazaki, K; Sudo, S; Matsuoka, K; Hamada, Y; Motojima, O; Fujiwara, M

2003-01-01

The behaviour of high-energy ions accelerated by an ion cyclotron range of frequency (ICRF) electric field in the large helical device (LHD) is discussed. A better confinement performance of high-energy ions in the inward-shifted magnetic axis configuration was experimentally verified by measuring their energy spectrum and comparing it with the effective temperature determined by an electron slowing down process. In the standard magnetic axis configuration a saturation of the measured tail temperature was observed as the effective temperature was increased. The ratio between these two quantities is a measure of the quality of transfer efficiency from high-energy ions to a bulk plasma; when this efficiency was compared with Monte Carlo simulations the results agreed fairly well. The ratio of the stored energy of the high-energy ions to that of the bulk plasma was measured using an ICRF heating power modulation method; it was deduced from phase differences between total and bulk plasma stored energies and the modulated ICRF heating power. The measured high energy fraction agreed with that calculated using the injected ICRF heating power, the transfer efficiency determined in the experiment and the confinement scaling of the LHD plasma

Is it possible to treat produced water for recycle and beneficial reuse?

Energy Technology Data Exchange (ETDEWEB)

Hum, F.; Tsang, P.; Kantzas, A.; Harding, T. [Calgary Univ., AB (Canada). Tomographic Imaging and Porous Media Laboratory

2005-11-01

In 2003, the oil and gas industry in Alberta injected 0.3 billion cubic metres of produced water into disposal wells. This paper addressed the issue of using the large volume of produced water for recycling and make water reuse a sustainable activity in Alberta to reduce fresh water demand. Although produced water represents a potential resource for recycling and beneficial reuse, it must first be treated to meet water quality criteria and regulatory guidelines for specific applications. A comprehensive technical and economic review of water treatment technologies was presented. Commonly used and new water desalination technologies were reviewed and key challenges associated with the recycling of produced water were identified. It was shown that water treatment processes are commercially available and that they are not prohibitively expensive. However, the cost of implementing treating processes to meet drinking water quality guidelines is about 3 times the current cost of municipal water supply in Alberta. For that reason, it is more feasible to recycle waste water for agricultural or petroleum applications, such as waterflooding. The water quality guidelines for these other purposes are less stringent than for drinking water and there is also growing public resistance for industry to use fresh water for commercial use. 42 refs., 3 tabs., 14 figs.

Productive international collaboration in the large coil task

International Nuclear Information System (INIS)

Haubenreich, P.N.; Komarek, P.; Shimamoto, S.; Vecsey, G.

1987-01-01

The Large Coil Task (LCT), initiated in 1977, has been very productive of useful technical information about superconducting toroidal field (TF) coil design and manufacture. Moreover, it has demonstrated close international collaboration in fusion technology development, including integration of large components built in four different countries. Each of six 40-t test coils was designed and produced by a major industrial team, with government laboratory guidance, to a common set of specifications. The six were assembled into a toroidal array for testing in the International Fusion Superconducting Magnet Test Facility (IFSMTF) at Oak Ridge. Testing was done by a team of representatives of EURATOM, Japan, Switzerland, and the United States, with each participant having full access to all data. Coils were thoroughly instrumented, enabling penetrating analysis of behavior

Non-invasive rapid harvest time determination of oil-producing microalgae cultivations for bio-diesel production by using Chlorophyll fluorescence

Directory of Open Access Journals (Sweden)

Yaqin eQiao

2015-10-01

Full Text Available For the large-scale cultivation of microalgae for biodiesel production, one of the key problems is the determination of the optimum time for algal harvest when algae cells are saturated with neutral lipids. In this study, a method to determine the optimum harvest time in oil-producing microalgal cultivations by measuring the maximum photochemical efficiency of photosystem II (PSII, also called Fv/Fm, was established. When oil-producing Chlorella strains were cultivated and then treated with nitrogen starvation, it not only stimulated neutral lipid accumulation, but also affected the photosynthesis system, with the neutral lipid contents in all four algae strains – Chlorella sorokiniana C1, Chlorella sp. C2, C. sorokiniana C3, C. sorokiniana C7 – correlating negatively with the Fv/Fm values. Thus, for the given oil-producing algae, in which a significant relationship between the neutral lipid content and Fv/Fm value under nutrient stress can be established, the optimum harvest time can be determined by measuring the value of Fv/Fm. It is hoped that this method can provide an efficient way to determine the harvest time rapidly and expediently in large-scale oil-producing microalgae cultivations for biodiesel production.

The CTIO surveys for large redshift quasars

International Nuclear Information System (INIS)

Osmer, P.S.

1978-01-01

Lyman α emission in large redshift quasars is readily detectable on slitless spectrograms taken with an objective combination on the 4m telescope. This provides a new survey method, independent of color for finding radio-quiet quasars in large numbers. Surveys by Smith with the Curtis Schmidt and Hoag and Smith with the 4 m telescope, have produced more than 200 candidates with 1.5< z<3.5 and 16< m<21. Spectroscopic observations with the CTIO SIT vidicon system have been carried out for more than 50 of the candidates, with the result that the basic properties of the surveys are known. To date three 16th magnitude quasars with zapproximately2.2 and six quasars with 3.0< z<3.25 have been found. One of the most important uses of the surveys will be the determination of the surface and surface densities of large redshift quasars. A preliminary analysis of the data indicates that the space density of quasars is at least constant, if not increasing, over the interval 1.0< z<3.25. However, the Hoag-Smith sample has only one candidate with z<3.2.(Auth.)

High plasma rotation velocity and density transitions by biased electrodes in RF produced, magnetized plasma

International Nuclear Information System (INIS)

Matsuyama, Shoichiro; Shinohara, Shunjiro

2001-01-01

A large density profile modification was successfully obtained by voltage biasing to electrodes inserted in a RF (radio frequency) produced, magnetized plasma, and formation of strong shear of azimuthal plasma rotation velocity in a supersonic regime was found. For the case of biasing to an electrode near the central plasma region, two types of density transitions were observed in the outer plasma region: one was an oscillatory transition between two states, and the other was a transition from high to low density states with a large reduction of density fluctuations. (author)

High plasma rotation velocity and density transitions by biased electrodes in RF produced, magnetized plasma

Energy Technology Data Exchange (ETDEWEB)

Matsuyama, Shoichiro; Shinohara, Shunjiro [Kyushu Univ., Interdisciplinary Graduate School of Engineering Sciences, Fukuoka (Japan)

2001-07-01

A large density profile modification was successfully obtained by voltage biasing to electrodes inserted in a RF (radio frequency) produced, magnetized plasma, and formation of strong shear of azimuthal plasma rotation velocity in a supersonic regime was found. For the case of biasing to an electrode near the central plasma region, two types of density transitions were observed in the outer plasma region: one was an oscillatory transition between two states, and the other was a transition from high to low density states with a large reduction of density fluctuations. (author)

Report of the large solenoid detector group

International Nuclear Information System (INIS)

Hanson, G.G.; Mori, S.; Pondrom, L.G.

1987-09-01

This report presents a conceptual design of a large solenoid for studying physics at the SSC. The parameters and nature of the detector have been chosen based on present estimates of what is required to allow the study of heavy quarks, supersymmetry, heavy Higgs particles, WW scattering at large invariant masses, new W and Z bosons, and very large momentum transfer parton-parton scattering. Simply stated, the goal is to obtain optimum detection and identification of electrons, muons, neutrinos, jets, W's and Z's over a large rapidity region. The primary region of interest extends over +-3 units of rapidity, although the calorimetry must extend to +-5.5 units if optimal missing energy resolution is to be obtained. A magnetic field was incorporated because of the importance of identifying the signs of the charges for both electrons and muons and because of the added possibility of identifying tau leptons and secondary vertices. In addition, the existence of a magnetic field may prove useful for studying new physics processes about which we currently have no knowledge. Since hermeticity of the calorimetry is extremely important, the entire central and endcap calorimeters were located inside the solenoid. This does not at the moment seem to produce significant problems (although many issues remain to be resolved) and in fact leads to a very effective muon detector in the central region

Traces of a large crocodylian from the Lower Cretaceous Sousa Formation, Brazil

DEFF Research Database (Denmark)

Campos, Herbert B.N.; da Silva, Rafael C.; Milàn, Jesper

2010-01-01

Body imprints and tracks attributed to large crocodylians from the Lower Cretaceous Sousa Formation of Brazil are described and interpreted as having been produced in a subaqueous environment. In addition to the crocodylian tracks, the assemblage also comprises isolated tracks from medium-sized t...

Microstructure and Textural Properties of Yoghurts Produced by Exopolysaccharides- Producing Starter Cultures

DEFF Research Database (Denmark)

Zhang, Lanjun

conferred a ropy texture and resulted in yoghurts with decreased water holding capacity and an open microstructure. In addition, one of the LB strains with high amounts of EPS producing capacity improved water retention, when it was combined with an ST strain that produced negligible amounts of EPS...

Large-D gravity and low-D strings.

Science.gov (United States)

Emparan, Roberto; Grumiller, Daniel; Tanabe, Kentaro

2013-06-21

We show that in the limit of a large number of dimensions a wide class of nonextremal neutral black holes has a universal near-horizon limit. The limiting geometry is the two-dimensional black hole of string theory with a two-dimensional target space. Its conformal symmetry explains the properties of massless scalars found recently in the large-D limit. For black branes with string charges, the near-horizon geometry is that of the three-dimensional black strings of Horne and Horowitz. The analogies between the α' expansion in string theory and the large-D expansion in gravity suggest a possible effective string description of the large-D limit of black holes. We comment on applications to several subjects, in particular to the problem of critical collapse.

Modeling Approach for Estimating Co-Produced Water Volumes and Saltwater Disposal Volumes in Oklahoma

Science.gov (United States)

Murray, K. E.

2016-12-01

Management of produced fluids has become an important issue in Oklahoma because large volumes of saltwater are co-produced with oil and gas, and disposed into saltwater disposal wells at high rates. Petroleum production increased from 2009-2015, especially in central and north-central Oklahoma where the Mississippian and Hunton zones were redeveloped using horizontal wells and dewatering techniques that have led to a disproportional increase in produced water volumes. Improved management of co-produced water, including desalination for beneficial reuse and decreased saltwater disposal volumes, is only possible if spatial and temporal trends can be defined and related to the producing zones. It is challenging to quantify the volumes of co-produced water by region or production zone because co-produced water volumes are generally not reported. Therefore, the goal of this research is to estimate co-produced water volumes for 2008-present with an approach that can be replicated as petroleum production shifts to other regions. Oil and gas production rates from subsurface zones were multiplied by ratios of H2O:oil and H2O:gas for the respective zones. Initial H2O:oil and H2O:gas ratios were adjusted/calibrated, by zone, to maximize correlation of county-scale produced H2O estimates versus saltwater disposal volumes from 2013-2015. These calibrated ratios were then used to compute saltwater disposal volumes from 2008-2012 because of apparent data gaps in reported saltwater disposal volumes during that timeframe. This research can be used to identify regions that have the greatest need for produced water treatment systems. The next step in management of produced fluids is to explore optimal energy-efficient strategies that reduce deleterious effects.

The seismic cycles of large Romanian earthquake: The physical foundation, and the next large earthquake in Vrancea

International Nuclear Information System (INIS)

Purcaru, G.

2002-01-01

event occurred in the 2nd band 2030-2040). Some times, more smaller HS zones can have synchronized FSL producing also such very large events, and (4) the smaller HS areas rupturing separately generate only large events (eg. 1986, 1990), also independently on depth. We conclude with the next large Vrancea earthquake predicted by the model in 2005, i.e. in the first time-band 2000-2010. (authors)

Producers give prices a boost

International Nuclear Information System (INIS)

Anon.

1992-01-01

Uranium producers came alive in August, helping spot prices crack the $8.00 barrier for the first time since March. The upper end of NUKEM's price range actually finished the month at $8.20. Scrambling to fulfill their long-term delivery contracts, producers dominate the market. In the span of three weeks, five producers came out for 2 million lbs U3O8, ultimately buying nearly 1.5 million lbs. One producer accounted for over half this volume. The major factor behind rising prices was that producers required specific origins to meet contract obligations. Buyers willing to accept open origins created the lower end of NUKEM's price range

Reuse of Produced Water from CO₂ Enhanced Oil Recovery, Coal-Bed Methane, and Mine Pool Water by Coal-Based Power Plants

Energy Technology Data Exchange (ETDEWEB)

Knutson, Chad [Univ. of Illinois, Champaign, IL (United States); Dastgheib, Seyed A. [Univ. of Illinois, Champaign, IL (United States); Yang, Yaning [Univ. of Illinois, Champaign, IL (United States); Ashraf, Ali [Univ. of Illinois, Champaign, IL (United States); Duckworth, Cole [Univ. of Illinois, Champaign, IL (United States); Sinata, Priscilla [Univ. of Illinois, Champaign, IL (United States); Sugiyono, Ivan [Univ. of Illinois, Champaign, IL (United States); Shannon, Mark A. [Univ. of Illinois, Champaign, IL (United States); Werth, Charles J. [Univ. of Illinois, Champaign, IL (United States)

2012-07-01

Power generation in the Illinois Basin is expected to increase by as much as 30% by the year 2030, and this would increase the cooling water consumption in the region by approximately 40%. This project investigated the potential use of produced water from CO₂ enhanced oil recovery (CO₂-EOR) operations; coal-bed methane (CBM) recovery; and active and abandoned underground coal mines for power plant cooling in the Illinois Basin. Specific objectives of this project were: (1) to characterize the quantity, quality, and geographic distribution of produced water in the Illinois Basin; (2) to evaluate treatment options so that produced water may be used beneficially at power plants; and (3) to perform a techno-economic analysis of the treatment and transportation of produced water to thermoelectric power plants in the Illinois Basin. Current produced water availability within the basin is not large, but potential flow rates up to 257 million liters per day (68 million gallons per day (MGD)) are possible if CO₂-enhanced oil recovery and coal bed methane recovery are implemented on a large scale. Produced water samples taken during the project tend to have dissolved solids concentrations between 10 and 100 g/L, and water from coal beds tends to have lower TDS values than water from oil fields. Current pretreatment and desalination technologies including filtration, adsorption, reverse osmosis (RO), and distillation can be used to treat produced water to a high quality level, with estimated costs ranging from $2.6 to $10.5 per cubic meter ($10 to $40 per 1000 gallons). Because of the distances between produced water sources and power plants, transportation costs tend to be greater than treatment costs. An optimization algorithm was developed to determine the lowest cost pipe network connecting sources and sinks. Total water costs increased with flow rate up to 26 million liters per day (7 MGD), and the range was from $4 to $16 per cubic meter

Producing the Spielberg Brand

OpenAIRE

Russell, J.

2016-01-01

This chapter looks at the manufacture of Spielberg’s brand, and the limits of its usage. Spielberg’s directorial work is well known, but Spielberg’s identity has also been established in other ways, and I focus particularly on his work as a producer. At the time of writing, Spielberg had produced (or executive produced) 148 movies and television series across a range of genres that takes in high budget blockbusters and low budget documentaries, with many more to come. In these texts, Spielber...

Off-diagonal helicity density matrix elements for vector mesons produced in polarized e+e- processes

International Nuclear Information System (INIS)

Anselmino, M.; Murgia, F.; Quintairos, P.

1999-04-01

Final state q q-bar interactions give origin to non zero values of the off-diagonal element ρ 1,-1 of the helicity density matrix of vector mesons produced in e + e - annihilations, as confirmed by recent OPAL data on φ, D * and K * 's. New predictions are given for ρ 1,-1 of several mesons produced at large x E and small p T - i.e. collinear with the parent jet - in the annihilation of polarized 3 + and 3 - , the results depend strongly on the elementary dynamics and allow further non trivial tests of the standard model. (author)

Very High Load Capacity Air Bearing Spindle for Large Diamond Turning Machines, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — Diamond turning is able to produce highly aspheric visible quality optics which can be easily aligned. Very large optical systems such as OWL and EUSO are impossible...

Temporal trends for dioxins-related agrochemicals in sediments in a large-scale rice-producing area, Niigata, Japan

Energy Technology Data Exchange (ETDEWEB)

Sakai, Mizuki; Hideo, Kajihara [Niigata Univ. (Japan). Graduate School of Science and Technology; Hiroaki, Muto; Yukio, Takahashi [Niigata Univ. (Japan). Faculty of Engineering

2004-09-15

Japanese people have historically eaten rice as the main grain constituent in their diet. In the past 50 years, a larger amount of agrochemicals have been applied to Japanese rice fields to increase rice production. Masunaga et al. reported that common Japanese agrochemicals such as pentachlorophenol (PCP) and chloronitrophen (CNP) used in rice fields in the past contain dioxins as impurities. Since Niigata Plain is the largest rice-producing area in Japan, the soil and/or sediment in the lower basin in Niigata Plain could be highly polluted. In the previous study, we measured the age of a sediment core and the amount of dioxins (PCDD/DFs) in Toyano Lagoon and estimated the historical trend and the sources of dioxin. Most of the sources of dioxin in Toyano Lagoon sediment were PCP and CNP. The aims of this work are to quantify the extent, clarify the historical trends of CNP and PCP pollution in the Toyano Lagoon sediment and consider the interrelation between them.

Polysaccharide-producing microalgae

Energy Technology Data Exchange (ETDEWEB)

Braud, J.P.; Chaumont, D.; Gudin, C.; Thepenier, C.; Chassin, P.; Lemaire, C.

1982-11-01

The production of extracellular polysaccharides is studied with Nostoc sp (cyanophycus), Porphiridium cruentum, Rhodosorus marinus, Rhodella maculata (rhodophyci) and Chlamydomonas mexicana (chlorophycus). The polysaccharides produced are separated by centrifugation of the culture then precipitation with alcohol. Their chemical structure was studied by infrared spectrometry and acid hydrolysis. By their rheological properties and especially their insensitivity to temperatrure and pH variations the polysaccharides produced by Porphryridium cruentum and Rhodella maculata appear as suitable candidates for industrial applications.

Adaptive evolution of drug targets in producer and non-producer organisms

DEFF Research Database (Denmark)

Hansen, Bjarne Gram; Sun, Xin E.; Genee, Hans Jasper

2012-01-01

MPA (mycophenolic acid) is an immunosuppressive drug produced by several fungi in Penicillium subgenus Penicillium. This toxic metabolite is an inhibitor of IMPDH (IMP dehydrogenase). The MPA-biosynthetic cluster of Penicillum brevicompactum contains a gene encoding a B-type IMPDH, IMPDH-B, which...... confers MPA resistance. Surprisingly, all members of the subgenus Penicillium contain genes encoding IMPDHs of both the A and B types, regardless of their ability to produce MPA. Duplication of the IMPDH gene occurred before and independently of the acquisition of the MPAbiosynthetic cluster. Both P....... brevicompactum IMPDHs are MPA-resistant, whereas the IMPDHs from a non-producer are MPA-sensitive. Resistance comes with a catalytic cost: whereas P. brevicompactum IMPDH-B is >1000-fold more resistant to MPA than a typical eukaryotic IMPDH, its value of kcat/Km is 0.5%of ‘normal’. Curiously, IMPDH...

Large area nuclear particle detectors using ET materials

International Nuclear Information System (INIS)

1987-08-01

The purpose of this SBIR Phase 1 feasibility effort was to demonstrate the usefulness of Quantex electron-trapping (ET) materials for spatial detection of nuclear particles over large areas. This demonstration entailed evaluating the prompt visible scintillation as nuclear particles impinged on films of ET materials, and subsequently detecting the nuclear particle impingement information pattern stored in the ET material, by means of the visible-wavelength luminescence produced by near-infrared interrogation. Readily useful levels of scintillation and luminescence outputs are demonstrated

Large-scale impact cratering on the terrestrial planets

International Nuclear Information System (INIS)

Grieve, R.A.F.

1982-01-01

The crater densities on the earth and moon form the basis for a standard flux-time curve that can be used in dating unsampled planetary surfaces and constraining the temporal history of endogenic geologic processes. Abundant evidence is seen not only that impact cratering was an important surface process in planetary history but also that large imapact events produced effects that were crucial in scale. By way of example, it is noted that the formation of multiring basins on the early moon was as important in defining the planetary tectonic framework as plate tectonics is on the earth. Evidence from several planets suggests that the effects of very-large-scale impacts go beyond the simple formation of an impact structure and serve to localize increased endogenic activity over an extended period of geologic time. Even though no longer occurring with the frequency and magnitude of early solar system history, it is noted that large scale impact events continue to affect the local geology of the planets. 92 references

Large displacement spring-like electro-mechanical thermal actuators with insulator constraint beams

Science.gov (United States)

Luo, J. K.; Fu, Y. Q.; Flewitt, A. J.; Spearing, S. M.; Fleck, N. A.; Milne, W. I.

2005-07-01

A number of in-plane spring-like micro-electro-thermal-actuators with large displacements were proposed. The devices take the advantage of the large difference in the thermal expansion coefficients between the conductive arms and the insulator clamping beams. The constraint beams in one type (the spring) of these devices are horizontally positioned to restrict the expansion of the active arms in the x-direction, and to produce a displacement in the y-direction only. In other two types of actuators (the deflector and the contractor), the constraint beams are positioned parallel to the active arms. When the constraint beams are on the inside of the active arms, the actuator produces an outward deflection in the y-direction. When they are on the outside of the active arms, the actuator produces an inward contraction. Analytical model and finite element analysis were used to simulate the performances. It showed that at a constant temperature, analytical model is sufficient to predict the displacement of these devices. The displacements are all proportional to the temperature and the number of the chevron sections. A two-mask process is under development to fabricate these devices, using Si3N4 as the insulator beams, and electroplated Ni as the conductive beams.

Screening and identification of a cutinase-producing Rhodotorula mucilaginosa and properties of the cutinase.

Science.gov (United States)

Zhang, Xiao-Ning; Ran, Qin-Qin; Zhang, Xuejun

2015-01-01

Eucommia leaf contains large amounts of natural active products. In extracting the substances, the most important is the removal of the cuticle layer on the leaves and the cell wall in the leaves of Eucommia ulmoides. But the removal of the cuticle layer is a technical difficulty now. Cutinase (EC3.1.1.74) is a multifunctional enzyme with a common alpha/beta fold structure belonging to hydroplane that can make a substantial degradation of horny fatty acids. So this study isolated bacteria capable of producing cutinase from the lesion of Eucommia leaves and identified the bacteria. The identification using PCR-RFLP method confirmed that the strain belongs to Rhodotorula mucilaginosa. The fermentation conditions of the strain-producing cutinase were optimized in this study. The finding of cutinase-producing R. mucilaginosa is significant because the yeast is more secure than plant pathogens, being suitable for mass production.

Beat map drawing method for large oriental bell based on operational deflection shape method

Energy Technology Data Exchange (ETDEWEB)

Lee, Joong Hyeok; Kim, Seock Hyun [Dept. of Advanced Mechanical Engineering, Kangwon National University, Chuncheon (Korea, Republic of); Park, In Seok [TB Tires Development 1 Team, R and D Center, Kumho Tire, Yongin (Korea, Republic of)

2016-10-15

Oriental bells produce a peculiar sound in the form of beats, which are periodic repetitions of strong and weak sounds. A beating sound with a proper period gives the illusion of the bell being alive and breathing. To produce a good beating sound, appropriate modal parameters are required for beat tuning after casting the bell. Conventionally, modal parameters were extracted using frequency response functions of the excitation and response signals. However, a large oriental bell is usually struck by a heavy wooden hammer and hence, only the response signal can be measured. In this study, we extract the modal parameters using the response signal only and employ the data to predict the beat properties of the bell sound. Finally, the validity of the predicted beat properties is experimentally verified for a large oriental bell.

Calculation of large Reynolds number two-dimensional flow using discrete vortices with random walk

International Nuclear Information System (INIS)

Milinazzo, F.; Saffman, P.G.

1977-01-01

The numerical calculation of two-dimensional rotational flow at large Reynolds number is considered. The method of replacing a continuous distribution of vorticity by a finite number, N, of discrete vortices is examined, where the vortices move under their mutually induced velocities plus a random component to simulate effects of viscosity. The accuracy of the method is studied by comparison with the exact solution for the decay of a circular vortex. It is found, and analytical arguments are produced in support, that the quantitative error is significant unless N is large compared with a characteristic Reynolds number. The mutually induced velocities are calculated by both direct summation and by the ''cloud in cell'' technique. The latter method is found to produce comparable error and to be much faster

Diddensiella caesifluorescens gen. nov., sp. nov., a riboflavin-producing yeast species of the family Trichomonascaceae

Science.gov (United States)

Four strains of a novel heterothallic yeast species were isolated from rotten wood collected in or near the Pilis Mountains in Hungary. The strains produced riboflavin in liquid culture. Analysis of gene sequences for the D1/D2 domains of the large subunit nuclear ribosomal RNA (rRNA), as well as an...

Development of a Large Area Advanced Fast RICH Detector for Particle Identification at the Large Hadron Collider Operated with Heavy Ions

CERN Multimedia

Piuz, F; Braem, A; Van beelen, J B; Lion, G; Gandi, A

2002-01-01

%RD26 %title\\\\ \\\\During the past two years, RD26 groups have focused their activities on the production of CsI-RICH prototypes of large area, up to a square meter, to demonstrate their application in High Energy experiments. Many large CsI-photocathodes (up to 40) were produced following the processing techniques furthermore developped in the collaboration. Taking the Quantum Efficiency (QE) measured at 180 nm as a comparative figure of merit of a CsI-PC. Figure 1 shows the increase of the performance while improvements were successively implemented in the PC processing sequence. Most efficient were the use of substrates made of nickel, the heat treatment and handling of the PCs under inert gas. Actually, three large systems based on CsI-RICH have got approval in the following HEP experiments: HADES at GSI, COMPASS/NA58 at CERN and HMPID/ALICE at LHC implying up to 14 square metres of CsI-PC. In addition, several CsI-RICH detectors have been successfully operated in the Threshold Imaging Detector at NA44 and ...

Pair creation at large inherent angles

International Nuclear Information System (INIS)

Chen, P.; Tauchi, T.; Schroeder, D.V.

1992-01-01

In the next-generation linear colliders, the low-energy e + e - pairs created during the collision of high-energy e + e - beams would cause potential deleterious background problems to the detectors. At low collider energies, the pairs are made essentially by the incoherent process, where the pair is created by the interaction of beamstrahlung photons on the individual particles in the oncoming beam. This problem was first identified by Zolotarev, et al. At energies where the beamstrahlung parameter Υ lies approximately in the range 0.6 approx-lt Υ approx-lt 100, pair creation from the beamstrahlung photons is dominated by a coherent process, first noted by Chen. The seriousness of this pair creation problem lies in the transverse momenta that the pair particles carry when leaving the interaction point (IP) with large angles. Since the central issue is the transverse momentum for particles with large angles, the authors notice that there is another source for it. Namely, when the pair particles are created at low energies, the intrinsic angles of these pairs when produced may already be large. In this paper they reinvestigate the problem, following essentially the same equivalent photon approach, but with changes in specific details including the virtual photon spectrum. In addition, various assumptions are made more explicit. The formulas derived are then applied to the collider parameters designed by Palmer

Large reservoirs: Chapter 17

Science.gov (United States)

Miranda, Leandro E.; Bettoli, Phillip William

2010-01-01

Large impoundments, defined as those with surface area of 200 ha or greater, are relatively new aquatic ecosystems in the global landscape. They represent important economic and environmental resources that provide benefits such as flood control, hydropower generation, navigation, water supply, commercial and recreational fisheries, and various other recreational and esthetic values. Construction of large impoundments was initially driven by economic needs, and ecological consequences received little consideration. However, in recent decades environmental issues have come to the forefront. In the closing decades of the 20th century societal values began to shift, especially in the developed world. Society is no longer willing to accept environmental damage as an inevitable consequence of human development, and it is now recognized that continued environmental degradation is unsustainable. Consequently, construction of large reservoirs has virtually stopped in North America. Nevertheless, in other parts of the world construction of large reservoirs continues. The emergence of systematic reservoir management in the early 20th century was guided by concepts developed for natural lakes (Miranda 1996). However, we now recognize that reservoirs are different and that reservoirs are not independent aquatic systems inasmuch as they are connected to upstream rivers and streams, the downstream river, other reservoirs in the basin, and the watershed. Reservoir systems exhibit longitudinal patterns both within and among reservoirs. Reservoirs are typically arranged sequentially as elements of an interacting network, filter water collected throughout their watersheds, and form a mosaic of predictable patterns. Traditional approaches to fisheries management such as stocking, regulating harvest, and in-lake habitat management do not always produce desired effects in reservoirs. As a result, managers may expend resources with little benefit to either fish or fishing. Some locally

The environmental impact of the use of large wind turbines

Science.gov (United States)

Manning, P. T.

The existing data base on the environmental impact of large wind energy conversion systems (WECS) is explored. The maximum blade throw distance has been calculated at 850 m, with a 5% probability of more than 300 m. Good design and inspection procedures reduce the risk. Ice throw can be prevented by aircraft deicing techniques, but detectors are still necessary. TV interference is ameliorated by the use of composite blades and directional antennas, by relocating the nearst transmission or relay station, or by introduction of cable TV. Microwave transmission effects can be avoided by careful siting of WECS in a favorable line of sight whenever within 1 km of a transmitter. Visual impact studies have produced few adverse opinions. Noise has not proved an intractable problem, although 30 dB levels have been exceeded 2100 m downwind of the Mod 2 WECS. Further studies are necessary on the effects of heightened ground turbulence produced by large WECS. It is expected that few birds will be harmed by slowly rotating blades in the birds' natural domain, a projection confirmed by sporadic studies. Finally, aircraft collisions are regarded as unlikely and actual land use, mostly confined to rural areas, is minimal.

The Asia Pacific natural gas market: Large enough for all?

International Nuclear Information System (INIS)

Aguilera, Roberto F.; Inchauspe, Julian; Ripple, Ronald D.

2014-01-01

Among natural gas producing nations, there has been some concern about how the Asia Pacific will meet future demand for energy. We argue that natural gas, both regional and global, will play a vital role. Estimates of potential gas consumption in the region are analyzed and used to develop consensus projections to 2030. These consumption profiles are compared with gas supply estimates including indigenous, pipeline and LNG for the Asia Pacific market. From this analytical framework, we find that demand will be sufficiently large to accommodate supplies from diverse sources including North America, the Middle East, Central Asia, Russia, and the Asia Pacific itself. An important policy implication is that gas producing and consuming nations should benefit from promoting gas trade and not be concerned about a situation of potential lack of demand coupled with oversupply. - Highlights: • Estimates of gas consumption in the Asia Pacific (AP) in 2030 are presented. • Compared with supply estimates for AP including indigenous, pipeline, and LNG. • Find that demand in AP large enough to accommodate supply from all regions. • Nations should promote gas trade policy and not be overly concerned about oversupply

Producing tantalum or columbium powder

International Nuclear Information System (INIS)

Rerat, C.F.

1979-01-01

A process is described for the production of tantalum or columbium powder with a high yield within a desired range of particle sizes. A molten salt bath of a double salt comprising either an alkali metal tantalum fluoride or an alkali metal columbium fluoride and a relatively large amount of alkali metal halide diluent salt to act as a heat sink is initially maintained at a temperature a little above the liquidus temperature of the salt mixture. A liquid alkali metal at a comparatively low temperature is added to the continuously stirred bath at a high mass flow rate, and reduces the double salt, producing tantalum or columbium. The reaction is exothermic and causes the temperature to rise rapidly to a desired final reaction temperature within the range 760 to 1000 0 . The liquid alkali metal is thereafter fed at a high mass flow rate to complete the reaction quickly at the final reaction temperature. Forced cooling at a heat extraction rate not less than 42 kilojoules/min./kg. of double salt is used during at least a portion of the reaction cycle at a rate sufficient to maintain the final reaction temperature within a desired range. (author)

A full picture of large lepton number asymmetries of the Universe

Energy Technology Data Exchange (ETDEWEB)

Barenboim, Gabriela [Departament de Física Teòrica and IFIC, Universitat de València-CSIC, C/ Dr. Moliner, 50, Burjassot, E-46100 Spain (Spain); Park, Wan-Il, E-mail: Gabriela.Barenboim@uv.es, E-mail: wipark@jbnu.ac.kr [Department of Science Education (Physics), Chonbuk National University, 567 Baekje-daero, Jeonju, 561-756 (Korea, Republic of)

2017-04-01

A large lepton number asymmetry of O(0.1−1) at present Universe might not only be allowed but also necessary for consistency among cosmological data. We show that, if a sizeable lepton number asymmetry were produced before the electroweak phase transition, the requirement for not producing too much baryon number asymmetry through sphalerons processes, forces the high scale lepton number asymmetry to be larger than about 03. Therefore a mild entropy release causing O(10-100) suppression of pre-existing particle density should take place, when the background temperature of the Universe is around T = O(10{sup −2}-10{sup 2}) GeV for a large but experimentally consistent asymmetry to be present today. We also show that such a mild entropy production can be obtained by the late-time decays of the saxion, constraining the parameters of the Peccei-Quinn sector such as the mass and the vacuum expectation value of the saxion field to be m {sub φ} ∼> O(10) TeV and φ{sub 0} ∼> O(10{sup 14}) GeV, respectively.

Electron beam producing system for very high acceleration voltages and beam powers

International Nuclear Information System (INIS)

Andelfinger, C.; Dommaschk, W.; Ott, W.; Ulrich, M.; Weber, G.

1975-01-01

An electron beam producing system for acceleration voltages on the order of megavolts and beam powers on the order of gigawatts is described. A tubular housing of insulating material is used, and adjacent to its one closed end, a field emission cathode with a large surface area is arranged, while at its other end, from which the electron beam emerges, an annular anode is arranged. The device for collimating the electron beam consists of annular electrodes. (auth)

Quantification and phenotypic characterisation of peripheral IFN-γ producing leucocytes in chickens vaccinated against Newcastle disease

DEFF Research Database (Denmark)

Andersen, Stig Henrik; Vervelde, Lonneke; Sutton, Kate

2017-01-01

controls, one group was vaccinated intramuscularly twice with a commercial inactivated ND virus (NDV) vaccine, and the last group was vaccinated orally twice with a commercial live attenuated NDV vaccine. PBMC were ex vivo stimulated with ConA or with NDV antigen. The ICS assay was used to determine...... the phenotype and frequency of IFN-γ positive cells. ConA stimulation induced extensive IFN-γ production in both CD3+TCRγδ+ (γδ T cells) cells and CD3+TCRγδ− cells (αβ T cells), but no significant differences were observed between the experimental groups. Furthermore, a large proportion of the IFN-γ producing...... cells were CD3− indicating that other cells than classic T cells, secreted this cytokine. NDV antigen stimulation induced IFN-γ production but to a lower extent than ConA and with a large variation between individuals. The CD3+TCR1γδ−CD8α+ (CTL) population produced the highest NDV specific IFN...

LHCb: Managing Large Data Productions in LHCb

CERN Multimedia

Tsaregorodtsev, A

2009-01-01

LHC experiments are producing very large volumes of data either accumulated from the detectors or generated via the Monte-Carlo modeling. The data should be processed as quickly as possible to provide users with the input for their analysis. Processing of multiple hundreds of terabytes of data necessitates generation, submission and following a huge number of grid jobs running all over the Computing Grid. Manipulation of these large and complex workloads is impossible without powerful production management tools. In LHCb, the DIRAC Production Management System (PMS) is used to accomplish this task. It enables production managers and end-users to deal with all kinds of data generation, processing and storage. Application workflow tools allow to define jobs as complex sequences of elementary application steps expressed as Directed Acyclic Graphs. Specialized databases and a number of dedicated software agents ensure automated data driven job creation and submission. The productions are accomplished by thorough ...

Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells

International Nuclear Information System (INIS)

Bodine, D.M.; McDonagh, K.T.; Brandt, S.J.; Ney, P.A.; Agricola, B.; Byrne, E.; Nienhuis, A.W.

1990-01-01

Retroviral-mediated gene transfer into primitive hematopoietic cells has been difficult to achieve in large-animal models. The authors have developed an amphotropic producer clone that generates >10 10 recombinant retroviral particles (colony-forming units) per ml of culture medium. Autologous rhesus monkey bone marrow cells were cocultured with either high or low titer producer clones for 4-6 days and reinfused into sublethally irradiated animals. The proviral genome was detected in blood and bone-marrow cells from all three animals reconstituted with cells cocultured with the high-titer producer cells. In contrast, three animals reconstituted with bone marrow cocultured with the low-titer producer clone exhibited no evidence of gene transfer

The welfare implications of large litter size in the domestic pig I

DEFF Research Database (Denmark)

Rutherford, K.M.D; Baxter, E.M.; D'Eath, R.B.

2013-01-01

Increasing litter size has long been a goal of pig breeders and producers, and may have implications for pig (Sus scrofa domesticus) welfare. This paper reviews the scientific evidence on biological factors affecting sow and piglet welfare in relation to large litter size. It is concluded that, i...

3D knitting using large circular knitting machines

Science.gov (United States)

Simonis, K.; Gloy, Y.-S.; Gries, T.

2017-10-01

For the first time 3D structures can now be produced on large circular knitting machines. Till date, such structures could only be manufactured on flat knitting machines. Since large circular knitting machines operate much faster, this development increases the overall productivity of 3D knits. It thus opens up a totally new avenue for cost reduction for applications in sportswear, upholstery, aerospace and automotive industry. The following paper presents the state of the art regarding the realisation of three dimensional fabrics. In addition, current knitting technologies regarding three dimensional formations will be explained. Results of the pretrials explaining the change in knitted fabrics´ dimension, executed at the Institut für Textiltechnik of the RWTH Aachen University, will be presented. Finally, the description of the 3D knit prototype developed will be provided as a part of this paper.

Active power reserves evaluation in large scale PVPPs

DEFF Research Database (Denmark)

Crăciun, Bogdan-Ionut; Kerekes, Tamas; Sera, Dezso

2013-01-01

The present trend on investing in renewable ways of producing electricity in the detriment of conventional fossil fuel-based plants will lead to a certain point where these plants have to provide ancillary services and contribute to overall grid stability. Photovoltaic (PV) power has the fastest...... growth among all renewable energies and managed to reach high penetration levels creating instabilities which at the moment are corrected by the conventional generation. This paradigm will change in the future scenarios where most of the power is supplied by large scale renewable plants and parts...... of the ancillary services have to be shared by the renewable plants. The main focus of the proposed paper is to technically and economically analyze the possibility of having active power reserves in large scale PV power plants (PVPPs) without any auxiliary storage equipment. The provided reserves should...

99mTc by 99Mo produced at the ENEA-FNG facility of 14MeV neutrons.

Science.gov (United States)

Capogni, M; Pietropaolo, A; Quintieri, L; Fazio, A; De Felice, P; Pillon, M; Pizzuto, A

2018-04-01

A severe supply crisis of 99 Mo, precursor of 99m Tc a diagnostic radionuclide largely used in Nuclear Medicine, occurred in 2008-2009 due to repeated shut-down of the two main (aged) fission reactors. An alternative route for producing 99 Mo by 100 Mo(n,2n) 99 Mo reaction was investigated at ENEA. The experiment, designed according to Monte Carlo simulations performed with the Fluka code, produced 99 Mo by irradiating a natural Molybdenum powdered target with 14MeV neutrons produced at the Frascati Neutron Generator. The 99 Mo specific activity was measured at metrological level by γ-ray spectrometry. Copyright © 2017 Elsevier Ltd. All rights reserved.

Risk Management of Large Component in Decommissioning

International Nuclear Information System (INIS)

Nah, Kyung Ku; Kim, Tae Ryong

2014-01-01

The need for energy, especially electric energy, has been dramatically increasing in Korea. Therefore, a rapid growth in nuclear power development has been achieved to have about 30% of electric power production. However, such a large nuclear power generation has been producing a significant amount of radioactive waste and other matters such as safety issue. In addition, owing to the severe accidents at the Fukushima in Japan, public concerns regarding NPP and radiation hazard have greatly increased. In Korea, the operation of KORI 1 has been scheduled to be faced with end of lifetime in several years and Wolsong 1 has been being under review for extending its life. This is the reason why the preparation of nuclear power plant decommissioning is significant in this time. Decommissioning is the final phase in the life-cycle of a nuclear facility and during decommissioning operation, one of the most important management in decommissioning is how to deal with the disused large component. Therefore, in this study, the risk in large component in decommissioning is to be identified and the key risk factor is to be analyzed from where can be prepared to handle decommissioning process safely and efficiently. Developing dedicated acceptance criteria for large components at disposal site was analyzed as a key factor. Acceptance criteria applied to deal with large components like what size of those should be and how to be taken care of during disposal process strongly affect other major works. For example, if the size of large component was not set up at disposal site, any dismantle work in decommissioning is not able to be conducted. Therefore, considering insufficient time left for decommissioning of some NPP, it is absolutely imperative that those criteria should be laid down

Risk Management of Large Component in Decommissioning

Energy Technology Data Exchange (ETDEWEB)

Nah, Kyung Ku; Kim, Tae Ryong [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

2014-10-15

The need for energy, especially electric energy, has been dramatically increasing in Korea. Therefore, a rapid growth in nuclear power development has been achieved to have about 30% of electric power production. However, such a large nuclear power generation has been producing a significant amount of radioactive waste and other matters such as safety issue. In addition, owing to the severe accidents at the Fukushima in Japan, public concerns regarding NPP and radiation hazard have greatly increased. In Korea, the operation of KORI 1 has been scheduled to be faced with end of lifetime in several years and Wolsong 1 has been being under review for extending its life. This is the reason why the preparation of nuclear power plant decommissioning is significant in this time. Decommissioning is the final phase in the life-cycle of a nuclear facility and during decommissioning operation, one of the most important management in decommissioning is how to deal with the disused large component. Therefore, in this study, the risk in large component in decommissioning is to be identified and the key risk factor is to be analyzed from where can be prepared to handle decommissioning process safely and efficiently. Developing dedicated acceptance criteria for large components at disposal site was analyzed as a key factor. Acceptance criteria applied to deal with large components like what size of those should be and how to be taken care of during disposal process strongly affect other major works. For example, if the size of large component was not set up at disposal site, any dismantle work in decommissioning is not able to be conducted. Therefore, considering insufficient time left for decommissioning of some NPP, it is absolutely imperative that those criteria should be laid down.

Producers and oil markets

International Nuclear Information System (INIS)

Greaves, W.

1993-01-01

This article attempts an assessment of the potential use of futures by the Middle East oil producers. It focuses on Saudi Arabia since the sheer size of Saudi Arabian sales poses problems, but the basic issues discussed are similar for the other Middle East producers. (Author)

Methods for the preparation of large quantities of complex single-stranded oligonucleotide libraries.

Science.gov (United States)

Murgha, Yusuf E; Rouillard, Jean-Marie; Gulari, Erdogan

2014-01-01

Custom-defined oligonucleotide collections have a broad range of applications in fields of synthetic biology, targeted sequencing, and cytogenetics. Also, they are used to encode information for technologies like RNA interference, protein engineering and DNA-encoded libraries. High-throughput parallel DNA synthesis technologies developed for the manufacture of DNA microarrays can produce libraries of large numbers of different oligonucleotides, but in very limited amounts. Here, we compare three approaches to prepare large quantities of single-stranded oligonucleotide libraries derived from microarray synthesized collections. The first approach, alkaline melting of double-stranded PCR amplified libraries with a biotinylated strand captured on streptavidin coated magnetic beads results in little or no non-biotinylated ssDNA. The second method wherein the phosphorylated strand of PCR amplified libraries is nucleolyticaly hydrolyzed is recommended when small amounts of libraries are needed. The third method combining in vitro transcription of PCR amplified libraries to reverse transcription of the RNA product into single-stranded cDNA is our recommended method to produce large amounts of oligonucleotide libraries. Finally, we propose a method to remove any primer binding sequences introduced during library amplification.

Active self-testing noise measurement sensors for large-scale environmental sensor networks.

Science.gov (United States)

Domínguez, Federico; Cuong, Nguyen The; Reinoso, Felipe; Touhafi, Abdellah; Steenhaut, Kris

2013-12-13

Large-scale noise pollution sensor networks consist of hundreds of spatially distributed microphones that measure environmental noise. These networks provide historical and real-time environmental data to citizens and decision makers and are therefore a key technology to steer environmental policy. However, the high cost of certified environmental microphone sensors render large-scale environmental networks prohibitively expensive. Several environmental network projects have started using off-the-shelf low-cost microphone sensors to reduce their costs, but these sensors have higher failure rates and produce lower quality data. To offset this disadvantage, we developed a low-cost noise sensor that actively checks its condition and indirectly the integrity of the data it produces. The main design concept is to embed a 13 mm speaker in the noise sensor casing and, by regularly scheduling a frequency sweep, estimate the evolution of the microphone's frequency response over time. This paper presents our noise sensor's hardware and software design together with the results of a test deployment in a large-scale environmental network in Belgium. Our middle-range-value sensor (around €50) effectively detected all experienced malfunctions, in laboratory tests and outdoor deployments, with a few false positives. Future improvements could further lower the cost of our sensor below €10.

Large psub(T) hadronic multiplicity in a two-jet model

International Nuclear Information System (INIS)

Aurenche, P.; Bopp, F.W.; Mestres, L.G.

1978-01-01

Using a standard parametrization of large psub(T) scattering and assuming the hard subprocess is mediated by a color octet exchange which produces two universally decaying high mass color singlet jets, the s and psub(T) dependence of the associated multiplicity is obtained. Good agreement with ISR data is found with a jet density of 1.1 charged particle per unit of rapidity. (Auth.)

Economics of producing hydrogen as transportation fuel using offshore wind energy systems

International Nuclear Information System (INIS)

Mathur, Jyotirmay; Agarwal, Nalin; Swaroop, Rakesh; Shah, Nikhar

2008-01-01

Over the past few years, hydrogen has been recognized as a suitable substitute for present vehicular fuels. This paper covers the economic analysis of one of the most promising hydrogen production methods-using wind energy for producing hydrogen through electrolysis of seawater-with a concentration on the Indian transport sector. The analysis provides insights about several questions such as the advantages of offshore plants over coastal installations, economics of large wind-machine clusters, and comparison of cost of producing hydrogen with competing gasoline. Robustness of results has been checked by developing several scenarios such as fast/slow learning rates for wind systems for determining future trends. Results of this analysis show that use of hydrogen for transportation is not likely to be attractive before 2012, and that too with considerable learning in wind, electrolyzer and hydrogen storage technology

A small quantity of sodium arsenite will kill large cull hardwoods

Science.gov (United States)

Francis M. Rushmore

1956-01-01

Although it is well known that sodium arsenite is an effective silvicide, forestry literature contains little information about the minimum quantities of this chemical that are required to kill large cull trees. Such information would be of value because if small quantities of a chemical will produce satisfactory results, small holes or frills in the tree will hold it...

Large-scale retrieval for medical image analytics: A comprehensive review.

Science.gov (United States)

Li, Zhongyu; Zhang, Xiaofan; Müller, Henning; Zhang, Shaoting

2018-01-01

Over the past decades, medical image analytics was greatly facilitated by the explosion of digital imaging techniques, where huge amounts of medical images were produced with ever-increasing quality and diversity. However, conventional methods for analyzing medical images have achieved limited success, as they are not capable to tackle the huge amount of image data. In this paper, we review state-of-the-art approaches for large-scale medical image analysis, which are mainly based on recent advances in computer vision, machine learning and information retrieval. Specifically, we first present the general pipeline of large-scale retrieval, summarize the challenges/opportunities of medical image analytics on a large-scale. Then, we provide a comprehensive review of algorithms and techniques relevant to major processes in the pipeline, including feature representation, feature indexing, searching, etc. On the basis of existing work, we introduce the evaluation protocols and multiple applications of large-scale medical image retrieval, with a variety of exploratory and diagnostic scenarios. Finally, we discuss future directions of large-scale retrieval, which can further improve the performance of medical image analysis. Copyright © 2017 Elsevier B.V. All rights reserved.

Science, Ethics and the Climate Responsibilities of Industrial Carbon Producers

Science.gov (United States)

Frumhoff, P. C.

2014-12-01

The question of responsibility for climate change lies at the heart of societal debate over actions to curb greenhouse gas emissions and prepare for now unavoidable climate impacts. The UN Framework Convention on Climate Change established the principle of "common but differentiated responsibilities" among nations, signaling the recognition that industrialized nations who had produced the lion's share of historic emissions bore particular responsibility for avoiding dangerous interference with the climate system. But climate responsibilities can be distributed in other ways as well. This talk focuses on the scientific, historical and ethical basis for considering the climate responsibilities of the major fossil energy companies that have produced and marketed the coal, oil and natural gas whose use largely drives global warming, often while investing in efforts to discredit the scientific evidence and prevent policies that would encourage a transition to low-carbon energy. Earth scientists and scientific societies who rely on financial support from these companies have an opportunity to consider what ethical stance they might take to align their research, scientific understanding and values.

The economics of producing biodiesel from algae

Energy Technology Data Exchange (ETDEWEB)

Gallagher, Brian J. [Ecotonics Environmental Scientists, 1801 Century Park East, Suite 2400, Los Angeles, CA 90067 (United States)

2011-01-15

Biodiesel is an alternative fuel for conventional diesel that is made from natural plant oils, animal fats, and waste cooking oils. This paper discusses the economics of producing biodiesel fuel from algae grown in open ponds. There is potential for large-scale production of biodiesel from algal farms on non-arable land; however, previous studies have failed to demonstrate an economically viable process that could be scalable to a commercialized industry. The problems include inconsistent and insufficient algal productivities, uncertain capital and operating costs, volatile market prices and unknown levels of government support. Although intensive work is being done on many technological issues, the economic studies and data are incomplete and out of date. This paper presents an updated financial analysis of the production and economic conditions that could have a profound effect on the success of this important alternative fuel production process. (author)

The economics of producing biodiesel from algae

International Nuclear Information System (INIS)

Gallagher, Brian J.

2011-01-01

Biodiesel is an alternative fuel for conventional diesel that is made from natural plant oils, animal fats, and waste cooking oils. This paper discusses the economics of producing biodiesel fuel from algae grown in open ponds. There is potential for large-scale production of biodiesel from algal farms on non-arable land; however, previous studies have failed to demonstrate an economically viable process that could be scalable to a commercialized industry. The problems include inconsistent and insufficient algal productivities, uncertain capital and operating costs, volatile market prices and unknown levels of government support. Although intensive work is being done on many technological issues, the economic studies and data are incomplete and out of date. This paper presents an updated financial analysis of the production and economic conditions that could have a profound effect on the success of this important alternative fuel production process. (author)

Eat healthy? Attitudes of the German population towards industrially produced cardioprotective food.

Science.gov (United States)

Jung, F U C E; Luck-Sikorski, C; Krüger, M; Wiacek, C; Braun, P G; Engeli, S; Riedel-Heller, S G

2018-05-01

Cardiovascular disease (CVD) is likely to increase in incidence. Foods with cardioprotective functions, e.g. specific functional food, could reduce CVD risk factors and hence CVD incidence. Little is known about industrially modified foods with cardioprotective functions. In a large German sample (n = 1007), attitudes of consumers in Germany towards industrially produced cardioprotective food were assessed using Cluster analyses. Consumers were contacted via telephone and interviewed using questionnaires. Overall, about 25% knew about industrially produced food with cardioprotective function. Our analysis revealed a small but determined group of consumers who think very skeptical about cardioprotective products, but we also identified a favorable group. These two groups only differed in age, with the skeptical group being ten years older. The rising number of industrially modified products with potential cardioprotective benefit is met by skepticism and a lack of knowledge by German costumers. If large scale studies show health benefits of these products, these will need to be better communicated to German customers in order to address possible doubts or concerns and to encourage healthy eating habits in consumer eating behavior. Copyright © 2018 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Search for Light Dark Matter Produced in a Proton Beam Dump

Energy Technology Data Exchange (ETDEWEB)

Thornton, Remington Tyler [Indiana Univ., Bloomington, IN (United States)

2017-01-01

Cosmological observations indicate that our universe contains dark matter (DM), yet we have no measurements of its microscopic properties. Whereas the gravitational interaction of DM is well understood, its interaction with the Standard Model is not. Direct detection experiments, the current standard, search for a nuclear recoil interaction and have a low-mass sensitivity edge of order 1 GeV. A path to detect DM with mass below 1 GeV is the use of accelerators producing boosted low-mass DM. Using neutrino detectors to search for low-mass DM is logical due to the similarity of the DM and neutrino signatures in the detector. The MiniBooNE experiment, located at Fermilab on the Booster Neutrino Beamline, has produced the first proton beam-dump light DM search results. Using dark matter scattering from nucleons 90% confidence limits were set over a large parameter space and, to allow tests of other theories, a model independent DM rate was extracted.

Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension.

Science.gov (United States)

Wu, Jing; Montaniel, Kim Ramil C; Saleh, Mohamed A; Xiao, Liang; Chen, Wei; Owens, Gary K; Humphrey, Jay D; Majesky, Mark W; Paik, David T; Hatzopoulos, Antonis K; Madhur, Meena S; Harrison, David G

2016-02-01

Various hypertensive stimuli lead to exuberant adventitial collagen deposition in large arteries, exacerbating blood pressure elevation and end-organ damage. Collagen production is generally attributed to resident fibroblasts; however, other cells, including resident and bone marrow-derived stem cell antigen positive (Sca-1(+)) cells and endothelial and vascular smooth muscle cells, can produce collagen and contribute to vascular stiffening. Using flow cytometry and immunofluorescence, we found that adventitial Sca-1(+) progenitor cells begin to produce collagen and acquire a fibroblast-like phenotype in hypertension. We also found that bone marrow-derived cells represent more than half of the matrix-producing cells in hypertension, and that one-third of these are Sca-1(+). Cell sorting and lineage-tracing studies showed that cells of endothelial origin contribute to no more than one fourth of adventitial collagen I(+) cells, whereas those of vascular smooth muscle lineage do not contribute. Our findings indicate that Sca-1(+) progenitor cells and bone marrow-derived infiltrating fibrocytes are major sources of arterial fibrosis in hypertension. Endothelial to mesenchymal transition likely also contributes, albeit to a lesser extent and pre-existing resident fibroblasts represent a minority of aortic collagen-producing cells in hypertension. This study shows that vascular stiffening represents a complex process involving recruitment and transformation of multiple cells types that ultimately elaborate adventitial extracellular matrix. © 2015 American Heart Association, Inc.

An Axiomatic Analysis Approach for Large-Scale Disaster-Tolerant Systems Modeling

Directory of Open Access Journals (Sweden)

Theodore W. Manikas

2011-02-01

Full Text Available Disaster tolerance in computing and communications systems refers to the ability to maintain a degree of functionality throughout the occurrence of a disaster. We accomplish the incorporation of disaster tolerance within a system by simulating various threats to the system operation and identifying areas for system redesign. Unfortunately, extremely large systems are not amenable to comprehensive simulation studies due to the large computational complexity requirements. To address this limitation, an axiomatic approach that decomposes a large-scale system into smaller subsystems is developed that allows the subsystems to be independently modeled. This approach is implemented using a data communications network system example. The results indicate that the decomposition approach produces simulation responses that are similar to the full system approach, but with greatly reduced simulation time.

[Distiller Yeasts Producing Antibacterial Peptides].

Science.gov (United States)

Klyachko, E V; Morozkina, E V; Zaitchik, B Ts; Benevolensky, S V

2015-01-01

A new method of controlling lactic acid bacteria contamination was developed with the use of recombinant Saccharomyces cerevisiae strains producing antibacterial peptides. Genes encoding the antibacterial peptides pediocin and plantaricin with codons preferable for S. cerevisiae were synthesized, and a system was constructed for their secretory expression. Recombinant S. cerevisiae strains producing antibacterial peptides effectively inhibit the growth of Lactobacillus sakei, Pediacoccus pentasaceus, Pediacoccus acidilactici, etc. The application of distiller yeasts producing antibacterial peptides enhances the ethanol yield in cases of bacterial contamination. Recombinant yeasts producing the antibacterial peptides pediocin and plantaricin can successfully substitute the available industrial yeast strains upon ethanol production.

Creating Large Scale Database Servers

International Nuclear Information System (INIS)

Becla, Jacek

2001-01-01

The BaBar experiment at the Stanford Linear Accelerator Center (SLAC) is designed to perform a high precision investigation of the decays of the B-meson produced from electron-positron interactions. The experiment, started in May 1999, will generate approximately 300TB/year of data for 10 years. All of the data will reside in Objectivity databases accessible via the Advanced Multi-threaded Server (AMS). To date, over 70TB of data have been placed in Objectivity/DB, making it one of the largest databases in the world. Providing access to such a large quantity of data through a database server is a daunting task. A full-scale testbed environment had to be developed to tune various software parameters and a fundamental change had to occur in the AMS architecture to allow it to scale past several hundred terabytes of data. Additionally, several protocol extensions had to be implemented to provide practical access to large quantities of data. This paper will describe the design of the database and the changes that we needed to make in the AMS for scalability reasons and how the lessons we learned would be applicable to virtually any kind of database server seeking to operate in the Petabyte region

Creating Large Scale Database Servers

Energy Technology Data Exchange (ETDEWEB)

Becla, Jacek

2001-12-14

The BaBar experiment at the Stanford Linear Accelerator Center (SLAC) is designed to perform a high precision investigation of the decays of the B-meson produced from electron-positron interactions. The experiment, started in May 1999, will generate approximately 300TB/year of data for 10 years. All of the data will reside in Objectivity databases accessible via the Advanced Multi-threaded Server (AMS). To date, over 70TB of data have been placed in Objectivity/DB, making it one of the largest databases in the world. Providing access to such a large quantity of data through a database server is a daunting task. A full-scale testbed environment had to be developed to tune various software parameters and a fundamental change had to occur in the AMS architecture to allow it to scale past several hundred terabytes of data. Additionally, several protocol extensions had to be implemented to provide practical access to large quantities of data. This paper will describe the design of the database and the changes that we needed to make in the AMS for scalability reasons and how the lessons we learned would be applicable to virtually any kind of database server seeking to operate in the Petabyte region.

Catalytic Metal Free Production of Large Cage Structure Carbon Particles: A Candidate for Hydrogen Storage

Science.gov (United States)

Kimura, Yuki; Nuth, Joseph A., III; Ferguson, Frank T.

2005-01-01

We will demonstrate that carbon particles consisting of large cages can be produced without catalytic metal. The carbon particles were produced in CO gas as well as by introduction of 5% methane gas into the CO gas. The gas-produced carbon particles were able to absorb approximately 16.2 wt% of hydrogen. This value is 2.5 times higher than the 6.5 wt% goal for the vehicular hydrogen storage proposed by the Department of Energy in the USA. Therefore, we believe that this carbon particle is an excellent candidate for hydrogen storage for fuel cells.

PEDIATRIC URINARY INFECTIONS, CAUSED BY EXTENDED-SPECTRUM BETA-LACTAMASE - PRODUCING MICROORGANISMS IN VARNA, BULGARIA

Directory of Open Access Journals (Sweden)

Neli M. Ermenlieva

2016-05-01

Full Text Available Background: Extended-spectrum beta-lactamase (ESBLs producing bacteria are microorganisms which have the ability to hydrolyze β-lactame ring of a large part of the antibiotics, commonly used to treat bacterial infections including urinary tract infections. Purpose: The aim of this study is present the epidemiology of childhood urinary tract infections caused by ESBL-producing strains in Varna, Bulgaria. Material/methods: A total of 3895 urine samples of children patients (aged 0 to 18 years were examined during the period 2010-2012 for presence of ESBL-producing bacteria. Results: Six percent of the tested urinary samples were positive for ESBL production. All of the isolates were resistant to ampicillin, piperacillin, cephalothin, cefprozil, cefuroxime, ceftriaxone, ceftazidime, levofloxacin, cefaclor, but were were sensitive to meropenem and imipenem. Conclusions: Cephalosporins and penicillins are the most used antibiotics in Bulgaria, but they should be very precisely prescribed in medical practice, because otherwise preconditions for maintaining high share of ESBLs are created.

RNA-Seq Highlights High Clonal Variation in Monoclonal Antibody Producing CHO Cells

DEFF Research Database (Denmark)

Orellana, Camila A.; Marcellin, Esteban; Palfreyman, Robin W.

2018-01-01

The development of next-generation sequencing technologies has opened new opportunities to better characterize complex eukaryotic cells. Chinese hamster ovary (CHO) cells play a primary role in therapeutic protein production, with currently five of the top ten blockbuster drugs produced in CHO......-regulation of genes encoding secreted glycoproteins is found to be the most significant change. The large number of significant differences even between subclones challenges the notion of identifying and manipulating a few key genes to generate high production CHO cell lines....

Large-scale methanol plants. [Based on Japanese-developed process

Energy Technology Data Exchange (ETDEWEB)

Tado, Y

1978-02-01

A study was made on how to produce methanol economically which is expected as a growth item for use as a material for pollution-free energy or for chemical use, centering on the following subjects: (1) Improvement of thermal economy, (2) Improvement of process, and (3) Problems of hardware attending the expansion of scale. The results of this study were already adopted in actual plants, obtaining good results, and large-scale methanol plants are going to be realized.

RESOLVED IMAGES OF LARGE CAVITIES IN PROTOPLANETARY TRANSITION DISKS

International Nuclear Information System (INIS)

Andrews, Sean M.; Wilner, David J.; Espaillat, Catherine; Qi Chunhua; Brown, J. M.; Hughes, A. M.; Dullemond, C. P.; McClure, M. K.

2011-01-01

Circumstellar disks are thought to experience a rapid 'transition' phase in their evolution that can have a considerable impact on the formation and early development of planetary systems. We present new and archival high angular resolution (0.''3 ∼ 40-75 AU) Submillimeter Array (SMA) observations of the 880 μm (340 GHz) dust continuum emission from 12 such transition disks in nearby star-forming regions. In each case, we directly resolve a dust-depleted disk cavity around the central star. Using two-dimensional Monte Carlo radiative transfer calculations, we interpret these dust disk structures in a homogeneous, parametric model framework by reproducing their SMA continuum visibilities and spectral energy distributions. The cavities in these disks are large (R cav = 15-73 AU) and substantially depleted of small (∼μm-sized) dust grains, although their mass contents are still uncertain. The structures of the remnant material at larger radii are comparable to normal disks. We demonstrate that these large cavities are relatively common among the millimeter-bright disk population, comprising at least 1 in 5 (20%) of the disks in the bright half (and ≥26% of the upper quartile) of the millimeter luminosity (disk mass) distribution. Utilizing these results, we assess some of the physical mechanisms proposed to account for transition disk structures. As has been shown before, photoevaporation models do not produce the large cavity sizes, accretion rates, and disk masses representative of this sample. A sufficient decrease of the dust optical depths in these cavities by particle growth would be difficult to achieve: substantial growth (to meter sizes or beyond) must occur in large (tens of AU) regions of low turbulence without also producing an abundance of small particles. Given those challenges, we suggest instead that the observations are most commensurate with dynamical clearing due to tidal interactions with low-mass companions-very young (∼1 Myr) brown

AL-PAM assisted filtration of mature fine tailings produced from oil sands development

Energy Technology Data Exchange (ETDEWEB)

Alamgir, A.; Masliyah, J.; Xu, Z. [Alberta Univ., Edmonton, AB (Canada). Dept. of Chemical and Materials Engineering

2010-07-01

The inventory of mature fine tailings (MFT) produced by the oil sands extraction process continues to grow, and is considered as a long-term environmental liability. Large amounts of water are trapped in the MFT, and the tailings ponds present a threat to local wildlife and ecosystems. This PowerPoint presentation discussed a research project that is being conducted to identify conditions for producing stackable MFT deposits. The study is investigating various types and dosages of polymers and evaluating the degrees of MFT dilution and process configurations needed to maximize re-usable water recovery. Polymeric flocculants include AL-PAM and Magnafloc 1011. Settling tests have demonstrated that 50 ppm is the optimum dosage for both polymers when MFT is diluted to 5 wt percent solids, while 75 ppm of AL-PAM and 100 ppm of MF1011 are optimum dosages for MFT diluted to 10 wt percent solids. A novel supernatant filtration method was then used to produce filtration cakes and water. The study showed that the supernatant can be used to further dilute the MFTs. tabs., figs.

Molecular Detection of Aflatoxin Producing Strains of Aspergillus Flavus from Peanut (Arachis Hypogaea

Directory of Open Access Journals (Sweden)

Adeela Hussain

2015-02-01

Full Text Available Aflatoxins are the potential carcinogens produced as secondary metabolites by Aspergillus flavus. They have the ability to contaminate large number of food which ultimately affect the human population. Malt extract agar was selected for the growth of control stains of fungus. The aim of the study was to develop a reliable and quick method for the detection of aflatoxin producing strains in peanuts by using molecular approaches. Total 80 samples of infected peanuts were collected from four different cities of Punjab and checked for their aflatoxin contamination. For aflatoxin detection, three target genes nor1, ver1 and aflR were selected which was involved in the aflatoxin biosynthesis. In all examined cases, 24 out of 80 (30% samples successfully amplified all three genes indicating aflatoxigenic activity. Discrimination between aflatoxigenic and non-aflatoxigenic strains were also determined on the basis of amplification of these three target DNA fragments. In this study, it was also demonstrated that only specific strains were able to produce the aflatoxin contamination in peanuts.

Development of a Solid-State Fermentation System for Producing Bioethanol from Food Waste

Science.gov (United States)

Honda, Hiroaki; Ohnishi, Akihiro; Fujimoto, Naoshi; Suzuki, Masaharu

Liquid fermentation is the a conventional method of producing bioethanol. However, this method results in the formation of high concentrations waste after distillation and futher treatment requires more energy and is costly(large amounts of costly energy).Saccharification of dried raw garbage was tested for 12 types of Koji starters under the following optimum culture conditions: temperature of 30°C and initial moisture content of 50%.Among all the types, Aspergillus oryzae KBN650 had the highest saccharifying power. The ethanol-producing ability of the raw garbage was investigated for 72 strains of yeast, of which Saccharomyces cerevisiae A30 had the highest ethanol production(yield)under the following optimum conditions: 1 :1 ratio of dried garbage and saccharified garbage by weight, and initial moisture content of 60%. Thus, the solid-state fermentation system consisted of the following 4 processes: moisture control, saccharification, ethanol production and distillation. This system produced 0.6kg of ethanol from 9.6kg of garbage. Moreover the ethanol yield from all sugars was calculated to be 0.37.

Market restructuring and public incentives: the Turkish case of fresh produce marketing cooperatives

OpenAIRE

Lemeilleur, Sylvaine; Bignebat, Celine; Codron, Jean Marie; Humboldt University of Berlin

2006-01-01

Faced to the fast restructuring agrofood markets in Turkey, the Turkish State set up new institutional devices to support agricultural marketing cooperatives. This article analyses the dynamics of these public incentives towards producers’ organizations on the restructuration of the Turkish fresh fruit and vegetable market. The wholesale market law enacted 1995 established brokers on wholesale market halls who collected an atomized supply and guarantee the access of small producers to large s...

Search for a Higgs Boson Produced in Association with a W Boson at ATLAS

CERN Document Server

Ruckert, Benjamin

The Large Hadron Collider at CERN is the most modern proton-proton collider and data taking will start in 2009, with a centre-of-mass energy of 7 TeV. The ATLAS detector, which is one of two multi-purpose detectors at the Large Hadron Collider, is able to detect a Standard Model Higgs boson if it exists. This is one of the main tasks of the ATLAS experiment. This thesis deals with a Standard Model Higgs boson produced in association with a W boson. The Monte Carlo study is based on physics events generated at the nominal centre-of-mass energy of the Large Hadron Collider of 14 TeV. Large parts of this analysis have been done using the global Grid infrastructure of the Large Hadron Collider experiments. A mass range of the Higgs boson of mH = 130 - 190 GeV has been taken into account. In this mass range, the Higgs boson dominantly decays into a pair of W bosons, leading to initially three W bosons: WH -> WWW. Two orthogonal analysis channels have been investigated in detailed studies of the background properti...

Detection of Steganography-Producing Software Artifacts on Crime-Related Seized Computers

Directory of Open Access Journals (Sweden)

Asawaree Kulkarni

2009-06-01

Full Text Available Steganography is the art and science of hiding information within information so that an observer does not know that communication is taking place. Bad actors passing information using steganography are of concern to the national security establishment and law enforcement. An attempt was made to determine if steganography was being used by criminals to communicate information. Web crawling technology was used and images were downloaded from Web sites that were considered as likely candidates for containing information hidden using steganographic techniques. A detection tool was used to analyze these images. The research failed to demonstrate that steganography was prevalent on the public Internet. The probable reasons included the growth and availability of large number of steganography-producing tools and the limited capacity of the detection tools to cope with them. Thus, a redirection was introduced in the methodology and the detection focus was shifted from the analysis of the ‘product’ of the steganography-producing software; viz. the images, to the 'artifacts’ left by the steganography-producing software while it is being used to generate steganographic images. This approach was based on the concept of ‘Stego-Usage Timeline’. As a proof of concept, a sample set of criminal computers was scanned for the remnants of steganography-producing software. The results demonstrated that the problem of ‘the detection of the usage of steganography’ could be addressed by the approach adopted after the research redirection and that certain steganographic software was popular among the criminals. Thus, the contribution of the research was in demonstrating that the limitations of the tools based on the signature detection of steganographically altered images can be overcome by focusing the detection effort on detecting the artifacts of the steganography-producing tools.

A particle identification technique for large acceptance spectrometers

International Nuclear Information System (INIS)

Cappuzzello, F.; Cavallaro, M.; Cunsolo, A.; Foti, A.; Carbone, D.; Orrigo, S.E.A.; Rodrigues, M.R.D.

2010-01-01

A technique to identify the heavy ions produced in nuclear reactions is presented. It is based on the use of a hybrid detector, which measures the energy loss, the residual energy, the position and angle of the ions at the focal plane of a magnetic spectrometer. The key point is the use of a powerful algorithm for the reconstruction of the ion trajectory, which makes the technique reliable even with large acceptance optical devices. Experimental results with the MAGNEX spectrometer show a remarkable resolution of about 1/160 in the mass parameter.

Assessment of present and future large-scale semiconductor detector systems

International Nuclear Information System (INIS)

Spieler, H.G.; Haller, E.E.

1984-11-01

The performance of large-scale semiconductor detector systems is assessed with respect to their theoretical potential and to the practical limitations imposed by processing techniques, readout electronics and radiation damage. In addition to devices which detect reaction products directly, the analysis includes photodetectors for scintillator arrays. Beyond present technology we also examine currently evolving structures and techniques which show potential for producing practical devices in the foreseeable future

An automated system for the preparation of Large Size Dried (LSD) Spikes

International Nuclear Information System (INIS)

Verbruggen, A.; Bauwens, J.; Jakobsson, U.; Eykens, R.; Wellum, R.; Aregbe, Y.; Van De Steene, N.

2008-01-01

Large size dried (LSD) spikes have been produced to fulfill the existing requirement for reliable and traceable isotopic reference materials for nuclear safeguards. A system to produce certified nuclear isotopic reference material as a U/Pu mixture in the form of large size dried spikes, comparable to those produced using traditional methods has been installed in collaboration with Nucomat, a company with a recognized reputation in design and development of integrated automated systems. The major components of the system are a robot, two balances, a dispenser and a drying unit fitted into a glove box. The robot is software driven and designed to control all movements inside the glove-box, to identify unambiguously the penicillin vials with a bar-code reader, to dispense the LSD batch solution into the vials and to weigh the amount dispensed. The system functionality has been evaluated and the performance validated by comparing the results from a series of samples dispensed and weighed by the automated system with the results by manual substitution weighing. After applying the proper correction factors to the data from the automated system balance no significant difference was observed between the two. However, an additional component of uncertainty of 3*10 -4 is introduced in the uncertainty budget for the certified weights provided by the automatic system. (authors)

An automated system for the preparation of Large Size Dried (LSD) Spikes

Energy Technology Data Exchange (ETDEWEB)

Verbruggen, A.; Bauwens, J.; Jakobsson, U.; Eykens, R.; Wellum, R.; Aregbe, Y. [European Commission - Joint Research Centre, Institute for Reference Materials and Measurements (IRMM), Retieseweg 211, B2440 Geel (Belgium); Van De Steene, N. [Nucomat, Mercatorstraat 206, B9100 Sint Niklaas (Belgium)

2008-07-01

Large size dried (LSD) spikes have been produced to fulfill the existing requirement for reliable and traceable isotopic reference materials for nuclear safeguards. A system to produce certified nuclear isotopic reference material as a U/Pu mixture in the form of large size dried spikes, comparable to those produced using traditional methods has been installed in collaboration with Nucomat, a company with a recognized reputation in design and development of integrated automated systems. The major components of the system are a robot, two balances, a dispenser and a drying unit fitted into a glove box. The robot is software driven and designed to control all movements inside the glove-box, to identify unambiguously the penicillin vials with a bar-code reader, to dispense the LSD batch solution into the vials and to weigh the amount dispensed. The system functionality has been evaluated and the performance validated by comparing the results from a series of samples dispensed and weighed by the automated system with the results by manual substitution weighing. After applying the proper correction factors to the data from the automated system balance no significant difference was observed between the two. However, an additional component of uncertainty of 3*10{sup -4} is introduced in the uncertainty budget for the certified weights provided by the automatic system. (authors)

Generation of large-scale vorticity in rotating stratified turbulence with inhomogeneous helicity: mean-field theory

Science.gov (United States)

Kleeorin, N.

2018-06-01

We discuss a mean-field theory of the generation of large-scale vorticity in a rotating density stratified developed turbulence with inhomogeneous kinetic helicity. We show that the large-scale non-uniform flow is produced due to either a combined action of a density stratified rotating turbulence and uniform kinetic helicity or a combined effect of a rotating incompressible turbulence and inhomogeneous kinetic helicity. These effects result in the formation of a large-scale shear, and in turn its interaction with the small-scale turbulence causes an excitation of the large-scale instability (known as a vorticity dynamo) due to a combined effect of the large-scale shear and Reynolds stress-induced generation of the mean vorticity. The latter is due to the effect of large-scale shear on the Reynolds stress. A fast rotation suppresses this large-scale instability.

Structural bursts produced by high energy muons in the rock

International Nuclear Information System (INIS)

Honda, K.; Takahashi, T.; Teramoto, Y.; Higashi, S.; Ozaki, S.

1975-01-01

Lateral structures of bursts produced by high energy muons in the rock have been observed at a depth 30 mw. e. underground by use of two layers of proportional counters. The running times were 7940 hr. The number of structural bursts observed, which have two cores in the both layers ( 1 >= 200, N 2 >= 20 particles) is 110, 1.6% of total events. These structural bursts have two types; 1) incident directions of two cores are parallel, 2) two cores intersect in the rock within 2 m above the roof of the tunnel. The events of this 2) type have large transverse momentum. (orig.) [de

Prevalence and risk factors of infections caused by extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae.

Science.gov (United States)

Nakai, Hazuki; Hagihara, Mao; Kato, Hideo; Hirai, Jun; Nishiyama, Naoya; Koizumi, Yusuke; Sakanashi, Daisuke; Suematsu, Hiroyuki; Yamagishi, Yuka; Mikamo, Hiroshige

2016-05-01

To study the clinical characteristics and associated risk factors of infections caused by extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae. A case-control study at a large university hospital in Japan, comparing patients who were infected or colonized with ESBL-producing Enterobacteriaceae (n = 212) and non-ESBL-producing Enterobacteriaceae (n = 2089) in 2010-2013. Data were collected from medical charts, retrospectively. Multivariate logistic regression analysis was used to explore risk factors of ESBL-producing Enterobacteriaceae (Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Proteus mirabilis) infection or colonization for each pathogen, respectively. ESBL-producing Enterobacteriaceae [E. coli (n = 113), K. oxytoca (n = 46), K. pneumoniae (n = 41), P. mirabilis (n = 12)] were taken from patients were identified in 1409 outpatient and 892 inpatients. Infection or colonization caused by ESBL-producing Enterobacteriaceae was considered to be hospital-acquired, healthcare-associated and community-acquired in 60.4%, 17.9% and 21.7% patients, respectively. Independent risk factors for ESBL-producing Enterobacteriaceae infection or colonization were male sex, cerebrovascular disease, intubation/tracheostomy, major surgery within 60 days (p  0.05). The problem of ESBL production is no longer limited to hospital-acquired infections. The presence of chronic illness, such as cerebrovascular disease, and recent antimicrobial use were independent risk factors for ESBL-producing Enterobacteriaceae infection or colonization. Copyright © 2016 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Performance of large electron energy filter in large volume plasma device

International Nuclear Information System (INIS)

Singh, S. K.; Srivastava, P. K.; Awasthi, L. M.; Mattoo, S. K.; Sanyasi, A. K.; Kaw, P. K.; Singh, R.

2014-01-01

This paper describes an in-house designed large Electron Energy Filter (EEF) utilized in the Large Volume Plasma Device (LVPD) [S. K. Mattoo, V. P. Anita, L. M. Awasthi, and G. Ravi, Rev. Sci. Instrum. 72, 3864 (2001)] to secure objectives of (a) removing the presence of remnant primary ionizing energetic electrons and the non-thermal electrons, (b) introducing a radial gradient in plasma electron temperature without greatly affecting the radial profile of plasma density, and (c) providing a control on the scale length of gradient in electron temperature. A set of 19 independent coils of EEF make a variable aspect ratio, rectangular solenoid producing a magnetic field (B x ) of 100 G along its axis and transverse to the ambient axial field (B z ∼ 6.2 G) of LVPD, when all its coils are used. Outside the EEF, magnetic field reduces rapidly to 1 G at a distance of 20 cm from the center of the solenoid on either side of target and source plasma. The EEF divides LVPD plasma into three distinct regions of source, EEF and target plasma. We report that the target plasma (n e ∼ 2 × 10 11  cm −3 and T e ∼ 2 eV) has no detectable energetic electrons and the radial gradients in its electron temperature can be established with scale length between 50 and 600 cm by controlling EEF magnetic field. Our observations reveal that the role of the EEF magnetic field is manifested by the energy dependence of transverse electron transport and enhanced transport caused by the plasma turbulence in the EEF plasma

On very-large-scale motions (VLSMs) and long-wavelength patterns in turbine wakes

Science.gov (United States)

Önder, Asim; Meyers, Johan

2017-11-01

It is now widely accepted that very-large-scale motions (VLSMs) are a prominent feature of thermally-neutral atmospheric boundary layers (ABL). Up to date, the influence of these very long active motions on wind-energy harvesting is not sufficiently explored. This work is an effort in this direction. We perform large-eddy simulation of a turbine row operating under neutral conditions. The ABL data is produced separately in a very long domain of 240 δ . VLSMs are isolated from smaller-scale ABL and wake motions using a spectral cutoff at streamwise wavelength λx = 3.125 δ . Reynolds-averaging of low-pass filtered fields shows that the interaction of VLSMs and turbines produce very-long-wavelength motions in the wake region, which contain about 20 % of the Reynolds-shear stress, and 30 % of the streamwise kinetic energy. A conditional analysis of filtered fields further reveals that these long-wavelength wakes are produced by modification of very long velocity streaks in ABL. In particular, the turbine row acts as a sharp boundary between low and high velocity streaks, and accompanying roller structures remain relatively unaffected. This reorganization creates a two-way flux towards the wake region, which elucidates the side-way domination in turbulent transport. The authors acknowledg funding from ERC Grant No 306471.

Large scale CMB anomalies from thawing cosmic strings

Energy Technology Data Exchange (ETDEWEB)

Ringeval, Christophe [Centre for Cosmology, Particle Physics and Phenomenology, Institute of Mathematics and Physics, Louvain University, 2 Chemin du Cyclotron, 1348 Louvain-la-Neuve (Belgium); Yamauchi, Daisuke; Yokoyama, Jun' ichi [Research Center for the Early Universe (RESCEU), Graduate School of Science, The University of Tokyo, Tokyo 113-0033 (Japan); Bouchet, François R., E-mail: christophe.ringeval@uclouvain.be, E-mail: yamauchi@resceu.s.u-tokyo.ac.jp, E-mail: yokoyama@resceu.s.u-tokyo.ac.jp, E-mail: bouchet@iap.fr [Institut d' Astrophysique de Paris, UMR 7095-CNRS, Université Pierre et Marie Curie, 98bis boulevard Arago, 75014 Paris (France)

2016-02-01

Cosmic strings formed during inflation are expected to be either diluted over super-Hubble distances, i.e., invisible today, or to have crossed our past light cone very recently. We discuss the latter situation in which a few strings imprint their signature in the Cosmic Microwave Background (CMB) Anisotropies after recombination. Being almost frozen in the Hubble flow, these strings are quasi static and evade almost all of the previously derived constraints on their tension while being able to source large scale anisotropies in the CMB sky. Using a local variance estimator on thousand of numerically simulated Nambu-Goto all sky maps, we compute the expected signal and show that it can mimic a dipole modulation at large angular scales while being negligible at small angles. Interestingly, such a scenario generically produces one cold spot from the thawing of a cosmic string loop. Mixed with anisotropies of inflationary origin, we find that a few strings of tension GU = O(1) × 10{sup −6} match the amplitude of the dipole modulation reported in the Planck satellite measurements and could be at the origin of other large scale anomalies.

Ultra-large single crystals by abnormal grain growth.

Science.gov (United States)

Kusama, Tomoe; Omori, Toshihiro; Saito, Takashi; Kise, Sumio; Tanaka, Toyonobu; Araki, Yoshikazu; Kainuma, Ryosuke

2017-08-25

Producing a single crystal is expensive because of low mass productivity. Therefore, many metallic materials are being used in polycrystalline form, even though material properties are superior in a single crystal. Here we show that an extraordinarily large Cu-Al-Mn single crystal can be obtained by abnormal grain growth (AGG) induced by simple heat treatment with high mass productivity. In AGG, the sub-boundary energy introduced by cyclic heat treatment (CHT) is dominant in the driving pressure, and the grain boundary migration rate is accelerated by repeating the low-temperature CHT due to the increase of the sub-boundary energy. With such treatment, fabrication of single crystal bars 70 cm in length is achieved. This result ensures that the range of applications of shape memory alloys will spread beyond small-sized devices to large-scale components and may enable new applications of single crystals in other metallic and ceramics materials having similar microstructural features.Growing large single crystals cheaply and reliably for structural applications remains challenging. Here, the authors combine accelerated abnormal grain growth and cyclic heat treatments to grow a superelastic shape memory alloy single crystal to 70 cm.

Human body may produce bacteria.

Science.gov (United States)

Salerian, Alen J

2017-06-01

"Human body may produce bacteria" proposes that human body may produce bacteria and represent an independent source of infections contrary to the current paradigm of infectious disorders proposed by Louis Pasteur in 1880. The following observations are consistent with this hypothesis: A. Bidirectional transformations of both living and nonliving things have been commonly observed in nature. B. Complex multicellular organisms harbor the necessary properties to produce bacteria (water, nitrogen and oxygen). C. Physical laws suggest any previously observed phenomenon or action will occur again (life began on earth; a non living thing). D. Animal muscle cells may generate energy (fermentation). E. Sterilized food products (i.e. boiled eggs), may produce bacteria and fungus under special conditions and without any exposure to foreign living cells. "Human body may produce bacteria" may challenge the current medical paradigm that views human infectious disorders as the exclusive causative byproducts of invading foreign cells. It may also introduce new avenues to treat infectious disorders. Copyright © 2017 Elsevier Ltd. All rights reserved.

Behavior of large grain UO{sub 2} pellet by new ADU powder

Energy Technology Data Exchange (ETDEWEB)

Harada, Y [Nuclear Development Corp., Tokai, Ibaraki (Japan); Doi, S [Mitsubishi Atomic Power Industries Inc., Kobe (Japan); Abeta, S [Mitsubishi Heavy Industries Ltd, Yokohama (Japan); Yamate, K [Kansai Electric Power Co., Inc., Osaka (Japan)

1997-08-01

In Japan, high burnup PWR fuel is being developed for assembly discharge burnups from 48 to 55GWd/t. As the pressure in the rods due to fission gas release from the pellets during the long burnup period is an important issue, some kinds of large grain pellets are being investigated in order to reduce fission gas release assuming their behavior will be as predicted by the simple diffusion mode. One kind of large grain pellet is manufactured from the highly sinterable powder produced by the new ADU (ammonium diuranate) process for converting UF{sub 6} gas to UO{sub 2+x} powder. First, we checked the difference in the characteristics of the new active powder and the one in current use by investigating its pelletizing (pressing and sintering), densification, grain growth and microstructure (pore and grain structure). Secondly, we measured the thermal creep, thermal expansion and thermal conductivity of the large grain pellet, in out-of-pile tests. As a results, it was found that the thermal properties of the large grain pellet are the same as those of the current. ADU pellet except for thermal densification and creep behavior. Thirdly, irradiation experiments were performed in the Halden test reactor and the pressure and fuel stack length change in the rods were monitored at power. After irradiation up to about 20GWd/t, PIE has been carried out. It was confirmed that the fission gas release of the large grain pellet is lower and the in-pile densification is smaller than for pellets in current use. The reduction due to the large grain size is lower than expected from the Booth model because the fission gas release rate is very small and the effect of recoil/knockout is comparable to that of diffusion for a low linear heat rate. This paper compares the microstructure of the new pellet with its large grains and pores produced by a performer and a current pellet with normal sized grains and intrinsic pores. It also describes how this comparison relates the in-pile behavior

Extracting the top-quark running mass using t anti t + 1-jet events produced at the Large Hadron Collider

Energy Technology Data Exchange (ETDEWEB)

Fuster, J.; Vos, M. [IFIC, Universitat de Valencia y CSIC, Paterna (Spain); Irles, A. [Universite de Paris-Sud XI, CNRS/IN2P3, Laboratoire de l' Accelerateur Lineaire, Orsay (France); Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Melini, D. [IFIC, Universitat de Valencia y CSIC, Paterna (Spain); Universidad de Granada, Departamento de Fisica Teorica y del Cosmos, Granada (Spain); Uwer, P. [Humboldt-Universitaet Berlin (Germany)

2017-11-15

We present the calculation of the next-to-leading order QCD corrections for top-quark pair production in association with an additional jet at hadron colliders, using the modified minimal subtraction scheme to renormalize the top-quark mass. The results are compared to measurements at the Large Hadron Collider run I. In particular, we determine the top-quark running mass from a fit of the theoretical results presented here to the LHC data. (orig.)

Extracting the top-quark running mass using t anti t+1-jet events produced at the Large Hadron Collider

Energy Technology Data Exchange (ETDEWEB)

Fuster, J.; Vos, M. [Valencia Univ. and CSIC, Paterna (Spain). IFIC; Irles, A. [Paris-Sud XI Univ., CNRS/IN2P3, Orsay (France). Lab. de l' Accelerateur Lineaire; Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Melini, D. [Valencia Univ. and CSIC, Paterna (Spain). IFIC; Granada Univ. (Spain). Dept. de Fisica Teorica y del Cosmos; Uwer, P. [Humboldt-Univ., Berlin (Germany)

2017-04-04

We present the calculation of the next-to-leading order QCD corrections for top quark pair production in association with an additional jet at hadron colliders, using the modified minimal subtraction scheme to renormalize the top-quark mass. The results are compared to measurements at the Large Hadron Collider run I. In particular, we determine the top-quark running mass from a fit of the theoretical results presented here to the LHC data.

Methods of producing transportation fuel

Science.gov (United States)

Nair, Vijay [Katy, TX; Roes, Augustinus Wilhelmus Maria [Houston, TX; Cherrillo, Ralph Anthony [Houston, TX; Bauldreay, Joanna M [Chester, GB

2011-12-27

Systems, methods, and heaters for treating a subsurface formation are described herein. At least one method for producing transportation fuel is described herein. The method for producing transportation fuel may include providing formation fluid having a boiling range distribution between -5.degree. C. and 350.degree. C. from a subsurface in situ heat treatment process to a subsurface treatment facility. A liquid stream may be separated from the formation fluid. The separated liquid stream may be hydrotreated and then distilled to produce a distilled stream having a boiling range distribution between 150.degree. C. and 350.degree. C. The distilled liquid stream may be combined with one or more additives to produce transportation fuel.

Recovery of Fresh Water Resources from Desalination of Brine Produced During Oil and Gas Production Operations

Energy Technology Data Exchange (ETDEWEB)

David B. Burnett; Mustafa Siddiqui

2006-12-29

Management and disposal of produced water is one of the most important problems associated with oil and gas (O&G) production. O&G production operations generate large volumes of brine water along with the petroleum resource. Currently, produced water is treated as a waste and is not available for any beneficial purposes for the communities where oil and gas is produced. Produced water contains different contaminants that must be removed before it can be used for any beneficial surface applications. Arid areas like west Texas produce large amount of oil, but, at the same time, have a shortage of potable water. A multidisciplinary team headed by researchers from Texas A&M University has spent more than six years is developing advanced membrane filtration processes for treating oil field produced brines The government-industry cooperative joint venture has been managed by the Global Petroleum Research Institute (GPRI). The goal of the project has been to demonstrate that treatment of oil field waste water for re-use will reduce water handling costs by 50% or greater. Our work has included (1) integrating advanced materials into existing prototype units and (2) operating short and long-term field testing with full size process trains. Testing at A&M has allowed us to upgrade our existing units with improved pre-treatment oil removal techniques and new oil tolerant RO membranes. We have also been able to perform extended testing in 'field laboratories' to gather much needed extended run time data on filter salt rejection efficiency and plugging characteristics of the process train. The Program Report describes work to evaluate the technical and economical feasibility of treating produced water with a combination of different separation processes to obtain water of agricultural water quality standards. Experiments were done for the pretreatment of produced water using a new liquid-liquid centrifuge, organoclay and microfiltration and ultrafiltration membranes

Maximal aerobic and anaerobic power generation in large crocodiles versus mammals: implications for dinosaur gigantothermy.

Science.gov (United States)

Seymour, Roger S

2013-01-01

Inertial homeothermy, the maintenance of a relatively constant body temperature that occurs simply because of large size, is often applied to large dinosaurs. Moreover, biophysical modelling and actual measurements show that large crocodiles can behaviourally achieve body temperatures above 30°C. Therefore it is possible that some dinosaurs could achieve high and stable body temperatures without the high energy cost of typical endotherms. However it is not known whether an ectothermic dinosaur could produce the equivalent amount of muscular power as an endothermic one. To address this question, this study analyses maximal power output from measured aerobic and anaerobic metabolism in burst exercising estuarine crocodiles, Crocodylusporosus, weighing up to 200 kg. These results are compared with similar data from endothermic mammals. A 1 kg crocodile at 30°C produces about 16 watts from aerobic and anaerobic energy sources during the first 10% of exhaustive activity, which is 57% of that expected for a similarly sized mammal. A 200 kg crocodile produces about 400 watts, or only 14% of that for a mammal. Phosphocreatine is a minor energy source, used only in the first seconds of exercise and of similar concentrations in reptiles and mammals. Ectothermic crocodiles lack not only the absolute power for exercise, but also the endurance, that are evident in endothermic mammals. Despite the ability to achieve high and fairly constant body temperatures, therefore, large, ectothermic, crocodile-like dinosaurs would have been competitively inferior to endothermic, mammal-like dinosaurs with high aerobic power. Endothermy in dinosaurs is likely to explain their dominance over mammals in terrestrial ecosystems throughout the Mesozoic.

Maximal aerobic and anaerobic power generation in large crocodiles versus mammals: implications for dinosaur gigantothermy.

Directory of Open Access Journals (Sweden)

Roger S Seymour

Full Text Available Inertial homeothermy, the maintenance of a relatively constant body temperature that occurs simply because of large size, is often applied to large dinosaurs. Moreover, biophysical modelling and actual measurements show that large crocodiles can behaviourally achieve body temperatures above 30°C. Therefore it is possible that some dinosaurs could achieve high and stable body temperatures without the high energy cost of typical endotherms. However it is not known whether an ectothermic dinosaur could produce the equivalent amount of muscular power as an endothermic one. To address this question, this study analyses maximal power output from measured aerobic and anaerobic metabolism in burst exercising estuarine crocodiles, Crocodylusporosus, weighing up to 200 kg. These results are compared with similar data from endothermic mammals. A 1 kg crocodile at 30°C produces about 16 watts from aerobic and anaerobic energy sources during the first 10% of exhaustive activity, which is 57% of that expected for a similarly sized mammal. A 200 kg crocodile produces about 400 watts, or only 14% of that for a mammal. Phosphocreatine is a minor energy source, used only in the first seconds of exercise and of similar concentrations in reptiles and mammals. Ectothermic crocodiles lack not only the absolute power for exercise, but also the endurance, that are evident in endothermic mammals. Despite the ability to achieve high and fairly constant body temperatures, therefore, large, ectothermic, crocodile-like dinosaurs would have been competitively inferior to endothermic, mammal-like dinosaurs with high aerobic power. Endothermy in dinosaurs is likely to explain their dominance over mammals in terrestrial ecosystems throughout the Mesozoic.

Renegotiating ethane contracts from producer/processor perspectives

International Nuclear Information System (INIS)

Hawkins, D. J.

1997-01-01

An overview of commercial practices relating to ethane sup ply and other collateral issues, including the variety of technologies used in the recovery of ethane and the manufacture of ethylene was provided. Ethane supply and demand balances, the Alberta ethane supply, the justifications for ethane recovery, the need for renegotiating ethane contracts in view of the changing Alberta market, the major price components , producers and processors' objectives in ethane sales, the nature of ethane contracts, and ethane pricing mechanisms were reviewed. The 'Alberta Advantage' based on gas price, large-scale ethane recovery, proximity to the largest market in the world, efficient transportation and fractionation facilities, further enhanced by deregulation and reduced regulatory barriers, was described. It was suggested that the enhanced competition and increase in market diversity demands a transparency in pricing that may well be realized as additional players enter the petrochemical business, and as competing transportation, processing and fractionation options become available to ethane suppliers and purchasers.1 tab

Effects of the oral administration of the exopolysaccharide produced by Lactobacillus kefiranofaciens on the gut mucosal immunity.

Science.gov (United States)

Vinderola, Gabriel; Perdigón, Gabriela; Duarte, Jairo; Farnworth, Edward; Matar, Chantal

2006-12-01

The probiotic effects ascribed to lactic acid bacteria (LAB) and their fermented dairy products arise not only from whole microorganisms and cell wall components but also from peptides and extracellular polysaccharides (exopolysaccharides) produced during the fermentation of milk. There is a lack of knowledge concerning the immune mechanisms induced by exopolysaccharides produced by lactic acid bacteria, which would allow a better understanding of the functional effects described to them. The aim of this study was to investigate the in vivo immunomodulating capacity of the exopolysaccharide produced by Lactobacillus kefiranofaciens by analyzing the profile of cytokines and immunoglobulins induced at the intestinal mucosa level, in the intestinal fluid and blood serum. BALB/c mice received the exopolysaccharide produced by L. kefiranofaciens for 2, 5 or 7 consecutive days. At the end of each period of administration, control and treated mice were sacrificed and the numbers of IgA+ and IgG+ cells were determined on histological slices of the small and large intestine by immunofluorescence. Cytokines (IL-4, IL-6, IL-10, IL-12, IFNgamma and TNFalpha) were also determined in the gut lamina propria as well as in the intestinal fluid and blood serum. There was an increase of IgA+ cells in the small and large intestine lamina propria, without change in the number of IgG+ cells in the small intestine. This study reports the effects of the oral administration of the exopolysaccharide produced by L. kefiranofaciens in the number of IgA+ cells in the small and large intestine, comparing simultaneously the production of cytokines by cells of the lamina propria and in the intestinal fluid and blood serum. The increase in the number of IgA+ cells was not simultaneously accompanied by an enhance of the number of IL-4+ cells in the small intestine. This finding would be in accordance with the fact that, in general, polysaccharide antigens elicit a T-independent immune response. For

How Large-Scale Research Facilities Connect to Global Research

DEFF Research Database (Denmark)

Lauto, Giancarlo; Valentin, Finn

2013-01-01

Policies for large-scale research facilities (LSRFs) often highlight their spillovers to industrial innovation and their contribution to the external connectivity of the regional innovation system hosting them. Arguably, the particular institutional features of LSRFs are conducive for collaborative...... research. However, based on data on publications produced in 2006–2009 at the Neutron Science Directorate of Oak Ridge National Laboratory in Tennessee (United States), we find that internationalization of its collaborative research is restrained by coordination costs similar to those characterizing other...

A Fast Shutdown Technique for Large Tokamaks

International Nuclear Information System (INIS)

Fredrickson, E.; Schmidt, G.L.; Hill, K.; Jardin, S.C.

1999-01-01

A practical method is proposed for the fast shutdown of a large ignited tokamak. The method consists of injecting a rapid series of 30-50 deuterium pellets doped with a small ( 0.0005%) concentration of Krypton impurity, and simultaneously ramping the plasma current and shaping fields down over a period of several seconds using the poloidal field system. Detailed modeling with the Tokamak Simulation Code using a newly developed pellet mass deposition model shows that this method should terminate the discharge in a controlled and stable way without producing significant numbers of runaway electrons. A partial prototyping of this technique was accomplished in TFTR

Large non-Gaussianity in non-minimal inflation

CERN Document Server

Gong, Jinn-Ouk

2011-01-01

We consider a simple inflation model with a complex scalar field coupled to gravity non-minimally. Both the modulus and the angular directions of the complex scalar are slowly rolling, leading to two-field inflation. The modulus direction becomes flat due to the non-minimal coupling, and the angular direction becomes a pseudo-Goldstone boson from a small breaking of the global U(1) symmetry. We show that large non-Gaussianity can be produced during slow-roll inflation under a reasonable assumption on the initial condition of the angular direction. This scenario may be realized in particle physics models such as the Standard Model with two Higgs doublets.

Large-scale anisotropy in the extragalactic gamma-ray background as a probe for cosmological antimatter

Science.gov (United States)

Gao, Yi-Tian; Stecker, Floyd W.; Gleiser, Marcelo; Cline, David B.

1990-01-01

Intrinsic anisotropies in the extragalactic gamma-ray background (EGB), which should be detectable with the forthcoming Gamma Ray Observatory, can be used to examine some of the mechanisms proposed to explain its origin, one of which, the baryon-symmetric big bang (BSBB) model, is investigated here. In this simulation, large domains containing matter and antimatter galaxies produce gamma rays by annihilation at the domain boundaries. This mechanism can produce mountain-chain-shaped angular fluctuations in the EGB flux.

Proposed method of producing large optical mirrors Single-point diamond crushing followed by polishing with a small-area tool

Science.gov (United States)

Wright, G.; Bryan, J. B.

1986-01-01

Faster production of large optical mirrors may result from combining single-point diamond crushing of the glass with polishing using a small area tool to smooth the surface and remove the damaged layer. Diamond crushing allows a surface contour accurate to 0.5 microns to be generated, and the small area computer-controlled polishing tool allows the surface roughness to be removed without destroying the initial contour. Final contours with an accuracy of 0.04 microns have been achieved.

Heliosphere Responds to a Large Solar Wind Intensification: Decisive Observations from IBEX

Science.gov (United States)

McComas, D. J.; Dayeh, M. A.; Funsten, H. O.; Heerikhuisen, J.; Janzen, P. H.; Reisenfeld, D. B.; Schwadron, N. A.; Szalay, J. R.; Zirnstein, E. J.

2018-03-01

Our heliosphere—the bubble in the local interstellar medium produced by the Sun’s outflowing solar wind—has finally responded to a large increase in solar wind output and pressure in the second half of 2014. NASA’s Interstellar Boundary Explorer (IBEX) mission remotely monitors the outer heliosphere by observing energetic neutral atoms (ENAs) returning from the heliosheath, the region between the termination shock and heliopause. IBEX observed a significant enhancement in higher energy ENAs starting in late 2016. While IBEX observations over the previous decade reflected a general reduction of ENA intensities, indicative of a deflating heliosphere, new observations show that the large (∼50%), persistent increase in the solar wind dynamic pressure has modified the heliosheath, producing enhanced ENA emissions. The combination of these new observations with simulation results indicate that this pressure is re-expanding our heliosphere, with the termination shock and heliopause already driven outward in the locations closest to the Sun. The timing between the IBEX observations, a large transient pressure enhancement seen by Voyager 2, and the simulations indicates that the pressure increase propagated through the heliosheath, reflected off the heliopause, and the enhanced density of the solar wind filled the heliosheath behind it before generating significantly enhanced ENA emissions. The coming years should see significant changes in anomalous cosmic rays, galactic cosmic radiation, and the filtration of interstellar neutral atoms into the inner heliosphere.

Thermoelectric and Structural Properties of Zr-/Hf-Based Half-Heusler Compounds Produced at a Large Scale

Science.gov (United States)

Zillmann, D.; Waag, A.; Peiner, E.; Feyand, M.-H.; Wolyniec, A.

2018-02-01

The half-Heusler (HH) systems are promising candidates for thermoelectric (TE) applications since they have shown high figures of merit ( zT) of ˜ 1, which are directly related to the energy conversion efficiency. To use HH compounds for TE devices, the materials must be phase-stable at operating temperatures up to 600°C. Currently, only a few HH compositions are available in large quantities. Hence, we focus on the TE and structural properties of three commercially available Zr-/Hf-based HH compounds in this publication. In particular, we evaluate the thermal conductivities and the figures of merit and critically discuss uncertainties and propagation error in the measurements. We find thermal conductivities of less than 6.0 W K^{-1}m^{-1} for all investigated materials and notably high figures of merit of 0.93 and 0.60 for n- and p-type compounds, respectively, at 600°C. Additionally, our investigations reveal that the grain structures of all materials also contain secondary phases like HfO2, Sn-Ni and Ti-Zr-Sn rich phases while an additional SnO_2 phase was found following several hours of harsh heat treatment at 800°C.

Development of metallic molds for the large volume plastic scintillator fabrication

International Nuclear Information System (INIS)

Calvo, Wilson A.P.; Vieira, Jose M.; Rela, Paulo R.; Bruzinga, Wilson A.; Araujo, Eduardo P.; Costa Junior, Nelson P.; Hamada, Margarida M.

1997-01-01

The plastic scintillators are radiation detectors made of organic fluorescent compounds dissolved in a solidified polymer matrix. The manufacturing process of large volume detectors (55 liters) at low cost, by polymerization of the styrene monomer plus PPO and POPOP scintillators, was studied in this paper. Metallic molds of ASTM 1200 aluminum and AISI 304 stainless steel were produced by TIG welding process since the polymerization reaction is very exothermic. The measurements of transmittance, luminescence, X-ray fluorescence and light output were carried out in the plastic scintillators made using different metallic molds. The characterization results of the detectors produced in an open system using ASTM 1200 aluminum mold show that there is not quality change in the scintillator, even with aluminum being considered as unstable for styrene monomer. Therefore, the ASTM 1200 aluminum was found to be the best alternative to produce the detector by an open system polymerization. (author). 11 refs., 8 figs., 1 tab

Price satisfaction and producer loyalty

DEFF Research Database (Denmark)

Mutonyi, Sarah; Beukel, Karin; Gyau, Amos

2016-01-01

Purpose The purpose of this paper is to investigate which dimensions of price satisfaction influence producers’ trust in buyers and assess the mediating role of such trust in the relationship between price satisfaction and producer loyalty in fresh fruit supply chains. Design/methodology/approach......Purpose The purpose of this paper is to investigate which dimensions of price satisfaction influence producers’ trust in buyers and assess the mediating role of such trust in the relationship between price satisfaction and producer loyalty in fresh fruit supply chains. Design...... reliability, and relative price are dimensions of price satisfaction that affect producers’ trust in the buyer. Moreover, trust between the producer and the buyer is found to be a strong mediator between price satisfaction and producer loyalty. The findings support recent studies about trust and its mediating...... between the multi-dimensional nature of price satisfaction and producer loyalty with trust as a mediating variable in the business-to-business (B2B) context. Although B2B relationships have been shown to be of great importance for smallholders in enhancing business performance with their buyers, little...

Repetition of large stress drop earthquakes on Wairarapa fault, New Zealand, revealed by LiDAR data

Science.gov (United States)

Delor, E.; Manighetti, I.; Garambois, S.; Beaupretre, S.; Vitard, C.

2013-12-01

We have acquired high-resolution LiDAR topographic data over most of the onland trace of the 120 km-long Wairarapa strike-slip fault, New Zealand. The Wairarapa fault broke in a large earthquake in 1855, and this historical earthquake is suggested to have produced up to 18 m of lateral slip at the ground surface. This would make this earthquake a remarkable event having produced a stress drop much higher than commonly observed on other earthquakes worldwide. The LiDAR data allowed us examining the ground surface morphology along the fault at statistical analysis of the cumulative offsets per segment reveals that the alluvial morphology has well recorded, at every step along the fault, no more than a few (3-6), well distinct cumulative slips, all lower than 80 m. Plotted along the entire fault, the statistically defined cumulative slip values document four, fairly continuous slip profiles that we attribute to the four most recent large earthquakes on the Wairarapa fault. The four slip profiles have a roughly triangular and asymmetric envelope shape that is similar to the coseismic slip distributions described for most large earthquakes worldwide. The four slip profiles have their maximum slip at the same place, in the northeastern third of the fault trace. The maximum slips vary from one event to another in the range 7-15 m; the most recent 1855 earthquake produced a maximum coseismic slip of 15 × 2 m at the ground surface. Our results thus confirm that the Wairarapa fault breaks in remarkably large stress drop earthquakes. Those repeating large earthquakes share both similar (rupture length, slip-length distribution, location of maximum slip) and distinct (maximum slip amplitudes) characteristics. Furthermore, the seismic behavior of the Wairarapa fault is markedly different from that of nearby large strike-slip faults (Wellington, Hope). The reasons for those differences in rupture behavior might reside in the intrinsic properties of the broken faults, especially

A combination of permanent magnet and magnetic coil for a large diameter ion source

International Nuclear Information System (INIS)

Uramoto, Joshin; Kubota, Yusuke; Miyahara, Akira.

1980-02-01

A large diameter ion source for fast neutral beam injection is designed under a magnetic field (we call ''Uramoto Field'') composed of a circular ferrite permanent magnet and a usual coreless magnetic coil. As the magnetic filed is reduced abruptly in a discharge anode, an ion source with a uniform ion current density over a large diameter is produced easily without a ''button'' of ORNL duoPIGatron type ion source (a floating electrode to diffuse an axial plasma flow radially). (author)

AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6

International Nuclear Information System (INIS)

Miles, S.A.; Rezai, A.R.; Salazar-Gonzalez, J.F.; Meyden, M.V.; Stevens, R.H.; Mitsuyasu, R.T.; Martinez-Maza, O.; Logan, D.M.; Taga, Tetsuya; Hirano, Toshio; Kishimoto, Tadamitsu

1990-01-01

Cell lines derived from Kaposi sarcoma lesions of patients with AIDS (AIDS-KS cells) produce several cytokines, including an endothelial cell growth factor, interleukin 1β, and basic fibroblast growth factor. Since exposure to human immunodeficiency virus increases interleukin 6 (IL-6) production in monocytes and endothelial cells produce IL-6, the authors examined IL-6 expression and response in AIDS-KS cell lines and IL-6 expression in AIDS Kaposi sarcoma tissue. The AIDS-KS cell lines (N521J and EKS3) secreted large amounts of immunoreactive and biologically active IL-6. The authors found both IL-6 and IL-6 receptor (IL-6-R) RNA by slot blot hybridization analysis of AIDS-KS cells. The IL-6-R was functional, as [ 3 H]thymidine incorporation by AIDS-KS cells increased significantly after exposure to human recombinant IL-6 (hrIL-6) at >10 units/ml. When AIDS-KS cells (EKS3) were exposed to IL-6 antisense oligonucleotide, cellular proliferation decreased by nearly two-thirds, with a corresponding decrease in the production of IL-6. These results show that both IL-6 and IL-6-R are produced by AIDS-KS cells and that IL-6 is required for optimal AIDS-KS cell proliferation, and they suggest that IL-6 is an autocrine growth factor for AIDS-KS cells

Bacteriocin producers from traditional food products

Directory of Open Access Journals (Sweden)

Thonart P.

2007-01-01

Full Text Available A total of 220 strains of LAB isolated from 32 samples of traditional fermented food from Senegal were screened for bacteriocin production. Two bacteriocin producers, Lactococcus lactis subsp. lactis and Enterococcus faecium, were identified from 12 bacteriocin-producing isolates on the basis of phenotypic analyses and 16S rDNA sequence. Both bacteriocins produced by new isolates show antimicrobial activity against Listeria monocytogenes and Bacillus coagulans whereas only that produced by Lactococcus lactis has an activity against Bacillus cereus. Bacteriocin-producing Lactococcus lactis strains were found in a variety of traditional foods indicating a high potential of growth of this strain in variable ecological complex environment. Partial 16S rDNA of the two bacteriocin producers obtained in this study has been registered to Genbank databases under the accession number AY971748 for Lactococcus lactis subsp. lactis (named CWBI-B1410 and AY971749 for Enterococcus faecium (named CWBI-B1411. The new bacteriocin-producing Lactococcus lactis subsp. lactis strain has been selected for identification and application of the bacteriocin to food preservation.

Forward production of J//psi/ in hadronic interactions and calibration of a large BGO electromagnetic calorimeter

International Nuclear Information System (INIS)

Kaaret, P.E.

1989-06-01

In the first part of this thesis, we describe an analysis of J//psi/ produced in the forward direction in the reaction πN → μ + μ/sup /minus//X. The data for this analysis were collected by Fermilab experiment E615. We measured the cross section for J//psi/ production and the angular distribution of muons from J//psi/ decay. We found evidence for longitudinal polarization of J//psi/ produced in the kinematic limit where the J//psi/ carries a large fraction of the incident pion's longitudinal momentum. This is the first experimental observation of longitudinal polarization of J//psi/ produced in hadronic interactions. In the second part of this thesis, we describe the construction and calibration of a large Bismuth Germanante (BGO) electromagnetic calorimeter designed to study e + e/sup /minus// collisions at center-of-mass energies near the Z 0 mass. The calorimeter is a subdetector of the L3 detector and will be installed in the Large Electron Positron collider (LEP) of the European Organization for Nuclear Research. We present the results of a calibration of the calorimeter in an electron test beam at electron energies of 2, 10, and 50 GeV. We show that the accuracy of the calibration is 0.8% at 2 GeV, improving to better than 0.5% at 10 GeV and above. 65 refs., 72 figs., 21 tabs

Body lift, drag and power are relatively higher in large-eared than in small-eared bat species.

Science.gov (United States)

Håkansson, Jonas; Jakobsen, Lasse; Hedenström, Anders; Johansson, L Christoffer

2017-10-01

Bats navigate the dark using echolocation. Echolocation is enhanced by external ears, but external ears increase the projected frontal area and reduce the streamlining of the animal. External ears are thus expected to compromise flight efficiency, but research suggests that very large ears may mitigate the cost by producing aerodynamic lift. Here we compare quantitative aerodynamic measures of flight efficiency of two bat species, one large-eared ( Plecotus auritus ) and one small-eared ( Glossophaga soricina ), flying freely in a wind tunnel. We find that the body drag of both species is higher than previously assumed and that the large-eared species has a higher body drag coefficient, but also produces relatively more ear/body lift than the small-eared species, in line with prior studies on model bats. The measured aerodynamic power of P. auritus was higher than predicted from the aerodynamic model, while the small-eared species aligned with predictions. The relatively higher power of the large-eared species results in lower optimal flight speeds and our findings support the notion of a trade-off between the acoustic benefits of large external ears and aerodynamic performance. The result of this trade-off would be the eco-morphological correlation in bat flight, with large-eared bats generally adopting slow-flight feeding strategies. © 2017 The Author(s).

Scaling A Moment-Rate Function For Small To Large Magnitude Events

Science.gov (United States)

Archuleta, Ralph; Ji, Chen

2017-04-01

Since the 1980's seismologists have recognized that peak ground acceleration (PGA) and peak ground velocity (PGV) scale differently with magnitude for large and moderate earthquakes. In a recent paper (Archuleta and Ji, GRL 2016) we introduced an apparent moment-rate function (aMRF) that accurately predicts the scaling with magnitude of PGA, PGV, PWA (Wood-Anderson Displacement) and the ratio PGA/2πPGV (dominant frequency) for earthquakes 3.3 ≤ M ≤ 5.3. This apparent moment-rate function is controlled by two temporal parameters, tp and td, which are related to the time for the moment-rate function to reach its peak amplitude and the total duration of the earthquake, respectively. These two temporal parameters lead to a Fourier amplitude spectrum (FAS) of displacement that has two corners in between which the spectral amplitudes decay as 1/f, f denotes frequency. At higher or lower frequencies, the FAS of the aMRF looks like a single-corner Aki-Brune omega squared spectrum. However, in the presence of attenuation the higher corner is almost certainly masked. Attempting to correct the spectrum to an Aki-Brune omega-squared spectrum will produce an "apparent" corner frequency that falls between the double corner frequency of the aMRF. We reason that the two corners of the aMRF are the reason that seismologists deduce a stress drop (e.g., Allmann and Shearer, JGR 2009) that is generally much smaller than the stress parameter used to produce ground motions from stochastic simulations (e.g., Boore, 2003 Pageoph.). The presence of two corners for the smaller magnitude earthquakes leads to several questions. Can deconvolution be successfully used to determine scaling from small to large earthquakes? Equivalently will large earthquakes have a double corner? If large earthquakes are the sum of many smaller magnitude earthquakes, what should the displacement FAS look like for a large magnitude earthquake? Can a combination of such a double-corner spectrum and random

Novel regenerative large-volume immobilized enzyme reactor: preparation, characterization and application.

Science.gov (United States)

Ruan, Guihua; Wei, Meiping; Chen, Zhengyi; Su, Rihui; Du, Fuyou; Zheng, Yanjie

2014-09-15

A novel large-volume immobilized enzyme reactor (IMER) on small column was prepared with organic-inorganic hybrid silica particles and applied for fast (10 min) and oriented digestion of protein. At first, a thin enzyme support layer was formed in the bottom of the small column by polymerization with α-methacrylic acid and dimethacrylate. After that, amino SiO2 particles was prepared by the sol-gel method with tetraethoxysilane and 3-aminopropyltriethoxysilane. Subsequently, the amino SiO2 particles were activated by glutaraldehyde for covalent immobilization of trypsin. Digestive capability of large-volume IMER for proteins was investigated by using bovine serum albumin (BSA), cytochrome c (Cyt-c) as model proteins. Results showed that although the sequence coverage of the BSA (20%) and Cyt-c (19%) was low, the large-volume IMER could produce peptides with stable specific sequence at 101-105, 156-160, 205-209, 212-218, 229-232, 257-263 and 473-451 of the amino sequence of BSA when digesting 1mg/mL BSA. Eight of common peptides were observed during each of the ten runs of large-volume IMER. Besides, the IMER could be easily regenerated by reactivating with GA and cross-linking with trypsin after breaking the -C=N- bond by 0.01 M HCl. The sequence coverage of BSA from regenerated IMER increased to 25% comparing the non-regenerated IMER (17%). 14 common peptides. accounting for 87.5% of first use of IMER, were produced both with IMER and regenerated IMER. When the IMER was applied for ginkgo albumin digestion, the sequence coverage of two main proteins of ginkgo, ginnacin and legumin, was 56% and 55%, respectively. (Reviewer 2) Above all, the fast and selective digestion property of the large-volume IMER indicated that the regenerative IMER could be tentatively used for the production of potential bioactive peptides and the study of oriented protein digestion. Copyright © 2014 Elsevier B.V. All rights reserved.

Search for pair-produced leptoquarks in $e^{+}e^{-}$ interactions at $\\sqrt{s} \\simeq$ 183 GeV

CERN Document Server

Abbiendi, G.; Alexander, G.; Allison, John; Anderson, K.J.; Anderson, S.; Arcelli, S.; Asai, S.; Ashby, S.F.; Axen, D.; Azuelos, G.; Ball, A.H.; Barberio, E.; Barlow, Roger J.; Batley, J.R.; Baumann, S.; Bechtluft, J.; Behnke, T.; Bell, Kenneth Watson; Bella, G.; Bellerive, A.; Bentvelsen, S.; Bethke, S.; Betts, S.; Biebel, O.; Biguzzi, A.; Bloodworth, I.J.; Bock, P.; Bohme, J.; Boeriu, O.; Bonacorsi, D.; Boutemeur, M.; Braibant, S.; Bright-Thomas, P.; Brigliadori, L.; Brown, Robert M.; Burckhart, H.J.; Capiluppi, P.; Carnegie, R.K.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, David G.; Chrisman, D.; Ciocca, C.; Clarke, P.E.L.; Clay, E.; Cohen, I.; Conboy, J.E.; Cooke, O.C.; Couchman, J.; Couyoumtzelis, C.; Coxe, R.L.; Cuffiani, M.; Dado, S.; Dallavalle, G.Marco; Dallison, S.; Davis, R.; De Jong, S.; de Roeck, A.; Dervan, P.; Desch, K.; Dienes, B.; Dixit, M.S.; Donkers, M.; Dubbert, J.; Duchovni, E.; Duckeck, G.; Duerdoth, I.P.; Estabrooks, P.G.; Etzion, E.; Fabbri, F.; Fanfani, A.; Fanti, M.; Faust, A.A.; Feld, L.; Ferrari, P.; Fiedler, F.; Fierro, M.; Fleck, I.; Frey, A.; Furtjes, A.; Futyan, D.I.; Gagnon, P.; Gary, J.W.; Gascon-Shotkin, S.M.; Gaycken, G.; Geich-Gimbel, C.; Giacomelli, G.; Giacomelli, P.; Gibson, W.R.; Gingrich, D.M.; Glenzinski, D.; Goldberg, J.; Gorn, W.; Grandi, C.; Graham, K.; Gross, E.; Grunhaus, J.; Gruwe, M.; Hajdu, C.; Hanson, G.G.; Hansroul, M.; Hapke, M.; Harder, K.; Harel, A.; Hargrove, C.K.; Harin-Dirac, M.; Hauschild, M.; Hawkes, C.M.; Hawkings, R.; Hemingway, R.J.; Herten, G.; Heuer, R.D.; Hildreth, M.D.; Hill, J.C.; Hobson, P.R.; Hocker, James Andrew; Hoffman, Kara Dion; Homer, R.J.; Honma, A.K.; Horvath, D.; Hossain, K.R.; Howard, R.; Huntemeyer, P.; Igo-Kemenes, P.; Imrie, D.C.; Ishii, K.; Jacob, F.R.; Jawahery, A.; Jeremie, H.; Jimack, M.; Jones, C.R.; Jovanovic, P.; Junk, T.R.; Kanaya, N.; Kanzaki, J.; Karlen, D.; Kartvelishvili, V.; Kawagoe, K.; Kawamoto, T.; Kayal, P.I.; Keeler, R.K.; Kellogg, R.G.; Kennedy, B.W.; Kim, D.H.; Klier, A.; Kobayashi, T.; Kobel, M.; Kokott, T.P.; Kolrep, M.; Komamiya, S.; Kowalewski, Robert V.; Kress, T.; Krieger, P.; von Krogh, J.; Kuhl, T.; Kyberd, P.; Lafferty, G.D.; Landsman, H.; Lanske, D.; Lauber, J.; Lawson, I.; Layter, J.G.; Lellouch, D.; Letts, J.; Levinson, L.; Liebisch, R.; Lillich, J.; List, B.; Littlewood, C.; Lloyd, A.W.; Lloyd, S.L.; Loebinger, F.K.; Long, G.D.; Losty, M.J.; Lu, J.; Ludwig, J.; Lui, D.; Macchiolo, A.; Macpherson, A.; Mader, W.; Mannelli, M.; Marcellini, S.; Marchant, T.E.; Martin, A.J.; Martin, J.P.; Martinez, G.; Mashimo, T.; Mattig, Peter; McDonald, W.John; McKenna, J.; Mckigney, E.A.; McMahon, T.J.; McPherson, R.A.; Meijers, F.; Mendez-Lorenzo, P.; Merritt, F.S.; Mes, H.; Meyer, I.; Michelini, A.; Mihara, S.; Mikenberg, G.; Miller, D.J.; Mohr, W.; Montanari, A.; Mori, T.; Nagai, K.; Nakamura, I.; Neal, H.A.; Nisius, R.; O'Neale, S.W.; Oakham, F.G.; Odorici, F.; Ogren, H.O.; Okpara, A.; Oreglia, M.J.; Orito, S.; Pasztor, G.; Pater, J.R.; Patrick, G.N.; Patt, J.; Perez-Ochoa, R.; Petzold, S.; Pfeifenschneider, P.; Pilcher, J.E.; Pinfold, J.; Plane, David E.; Poffenberger, P.; Poli, B.; Polok, J.; Przybycien, M.; Quadt, A.; Rembser, C.; Rick, H.; Robertson, S.; Robins, S.A.; Rodning, N.; Roney, J.M.; Rosati, S.; Roscoe, K.; Rossi, A.M.; Rozen, Y.; Runge, K.; Runolfsson, O.; Rust, D.R.; Sachs, K.; Saeki, T.; Sahr, O.; Sang, W.M.; Sarkisian, E.K.G.; Sbarra, C.; Schaile, A.D.; Schaile, O.; Scharff-Hansen, P.; Schieck, J.; Schmitt, S.; Schoning, A.; Schroder, Matthias; Schumacher, M.; Schwick, C.; Scott, W.G.; Seuster, R.; Shears, T.G.; Shen, B.C.; Shepherd-Themistocleous, C.H.; Sherwood, P.; Siroli, G.P.; Skuja, A.; Smith, A.M.; Snow, G.A.; Sobie, R.; Soldner-Rembold, S.; Spagnolo, S.; Sproston, M.; Stahl, A.; Stephens, K.; Stoll, K.; Strom, David M.; Strohmer, R.; Surrow, B.; Talbot, S.D.; Taras, P.; Tarem, S.; Teuscher, R.; Thiergen, M.; Thomas, J.; Thomson, M.A.; Torrence, E.; Towers, S.; Trefzger, T.; Trigger, I.; Trocsanyi, Z.; Tsur, E.; Turner-Watson, M.F.; Ueda, I.; Van Kooten, Rick J.; Vannerem, P.; Verzocchi, M.; Voss, H.; Wackerle, F.; Wagner, A.; Waller, D.; Ward, C.P.; Ward, D.R.; Watkins, P.M.; Watson, A.T.; Watson, N.K.; Wells, P.S.; Wermes, N.; Wetterling, D.; White, J.S.; Wilson, G.W.; Wilson, J.A.; Wyatt, T.R.; Yamashita, S.; Zacek, V.; Zer-Zion, D.

2000-01-01

A search for pair-produced leptoquarks has been performed using a sample of e+e- collision events collected by the OPAL detector at LEP at e+e- centre-of-mass energies of about 183 GeV. The data sample corresponds to an integrated luminosity of 55.9 pb-1. The leptoquarks were assumed to be produced via couplings to the photon and the Z0 and then to decay within a single fermion generation. No evidence for contributions from leptoquark pair production processes was observed. Lower limits on scalar and vector leptoquark masses are obtained. The existing limits are improved in the region of large decay branching ratio to quark-neutrino.

Power Electronic Drives, Controls, and Electric Generators for Large Wind Turbines - An Overview

DEFF Research Database (Denmark)

Ma, Ke; Tutelea, L.; Boldea, Ion

2015-01-01

and exceed a power rating of 10 MW are discussed. The role of power electronics for improving the operation of wind turbines and ensuring compliance with power grid codes is analyzed with a view at producing fully controllable generation units suitable for tight integration into the power grid and large...

Methods for producing diterpenes

DEFF Research Database (Denmark)

2015-01-01

The present invention discloses that by combining different di TPS enzymes of class I and class II different diterpenes may be produced including diterpenes not identified in nature. Surprisingly it is revealed that a di TPS enzyme of class I of one species may be combined with a di TPS enzyme...... of class II from a different species, resulting in a high diversity of diterpenes, which can be produced....

LLNL large-area inductively coupled plasma (ICP) source: Experiments

International Nuclear Information System (INIS)

Richardson, R.A.; Egan, P.O.; Benjamin, R.D.

1995-05-01

We describe initial experiments with a large (76-cm diameter) plasma source chamber to explore the problems associated with large-area inductively coupled plasma (ICP) sources to produce high density plasmas useful for processing 400-mm semiconductor wafers. Our experiments typically use a 640-nun diameter planar ICP coil driven at 13.56 MHz. Plasma and system data are taken in Ar and N 2 over the pressure range 3-50 mtorr. RF inductive power was run up to 2000W, but typically data were taken over the range 100-1000W. Diagnostics include optical emission spectroscopy, Langmuir probes, and B probes as well as electrical circuit measurements. The B and E-M measurements are compared with models based on commercial E-M codes. Initial indications are that uniform plasmas suitable for 400-mm processing are attainable

Large-Area Synthesis of High-Quality Uniform Few-Layer MoTe2.

Science.gov (United States)

Zhou, Lin; Xu, Kai; Zubair, Ahmad; Liao, Albert D; Fang, Wenjing; Ouyang, Fangping; Lee, Yi-Hsien; Ueno, Keiji; Saito, Riichiro; Palacios, Tomás; Kong, Jing; Dresselhaus, Mildred S

2015-09-23

The controlled synthesis of large-area, atomically thin molybdenum ditelluride (MoTe2) crystals is crucial for its various applications based on the attractive properties of this emerging material. In this work, we developed a chemical vapor deposition synthesis to produce large-area, uniform, and highly crystalline few-layer 2H and 1T' MoTe2 films. It was found that these two different phases of MoTe2 can be grown depending on the choice of Mo precursor. Because of the highly crystalline structure, the as-grown few-layer 2H MoTe2 films display electronic properties that are comparable to those of mechanically exfoliated MoTe2 flakes. Our growth method paves the way for the large-scale application of MoTe2 in high-performance nanoelectronics and optoelectronics.

Fabrication of large diameter alumino-silicate K+ sources

International Nuclear Information System (INIS)

Baca, D.; Chacon-Golcher, E.; Kwan, J.W.; Wu, J.K.

2003-01-01

Alumino-silicate K + sources have been used in HIF experiments for many years. For example the Neutralized Transport Expt. (NTX) and the High Current Transport Expt. (HCX) are now using this type of ion source with diameters of 2.54 cm and 10 cm respectively. These sources have demonstrated ion currents of 80 mA and 700 mA, for typical HIF pulse lengths of 5-10 (micro)s. The corresponding current density is ∼ 10-15 mA/cm 2 , but much higher current density has been observed using smaller size sources. Recently we have improved our fabrication techniques and, therefore, are able to reliably produce large diameter ion sources with high quality emitter surface without defects. This note provides a detailed description of the procedures employed in the fabrication process. The variables in the processing steps affecting surface quality, such as substrate porosity, powder size distribution, coating technique on large area concave surfaces, drying, and heat firing temperature have been investigated

Subharmonic edge waves on a large, shallow island

Science.gov (United States)

Foda, Mostafa A.

1988-08-01

Subharmonic resonance of edge waves by incident and reflected waves has been studied thus far for the case of a plane infinite beach. The analysis will be extended here to the case of a curved coastline, with a large radius of curvature and slowly varying beach slope in the longshore direction. It will be shown that the effects of such slow beach slope changes on a propagating edge wave are similar to the familiar shoaling effects on incident waves. The case of subharmonic edge wave generation on large shallow islands will be discussed in detail. The nonlinear analysis will show that within a certain range of island sizes, the generation mechanism can produce a stable standing edge wave around the island. For larger islands the solution disintegrates into two out-of-phase envelopes of opposite-going edge waves. For still larger islands, the generated progressive edge waves become unstable to sideband modulations.

Marketing and Socioeconomics Aspects of Large Cardamom Production in Tehrathum, Nepal

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Nirajan Bhandari

2018-05-01

Full Text Available A survey was conducted in November 2015 in one of the pocket area of large cardamom production in Teharthum District, eastern Nepal with aim to investigate the status of cardamom enterprises. The parameters used were cardamom production area, type of manure used, drying facilities, technical skills of farmers, market channels and variable cost etc. We purposively selected 30 cardamom producers and stakeholders for interview pre-designed questionnaires. The result showed that average area, production and productivity of large cardamom per household were 0.86 ha, 200 kg and 232 kg.ha-1, respectively, with the average farming experience of 22 years. It was revealed that 13% farmers used farmyard organic manure, the use of 1.5 kg/plant farmyard manure might produce 28.5% higher yield cardamom compared to without using any manure or fertilizers. It was also revealed among the responded only 7% had received improved drying machine from District Agriculture Development Office (DADO at 50% subsidy, while only 23% of farmers received training and technical services from DADO. The study showed that per hectare average total cost of large cardamom production, selling price and gross revenue were NRs. 2,36,705 ($2255, NRs. 5,50,305 ($5240 and NRs. 3,13,600 ($2985, respectively, with benefit/cost (B/C ratio of 2 after the completion of gestation period of 4 years. Our survey showed that predominant marketing approach was by direct sell to the traders located at district headquarter. The productivity of large cardamom was influenced by various factors, such as nearly 75.2% of the variation in productivity was explained by the number of active family members, farming period, area, intercultural operations, variable cost and depreciated fixed cost.

The global diversion of pharmaceutical drugs. India: the third largest illicit opium producer?

Science.gov (United States)

Paoli, Letizia; Greenfield, Victoria A; Charles, Molly; Reuter, Peter

2009-03-01

This paper explores India's role in the world illicit opiate market, particularly its role as a producer. India, a major illicit opiate consumer, is also the sole licensed exporter of raw opium: this unique status may be enabling substantial diversion to the illicit market. Participant observation and interviews were carried out at eight different sites. Information was also drawn from all standard secondary sources and the analysis of about 180 drug-related criminal proceedings reviewed by Indian High Courts and the Supreme Court from 1985 to 2001. Diversion from licit opium production takes place on such a large scale that India may be the third largest illicit opium producer after Afghanistan and Burma. With the possible exceptions of 2005 and 2006, 200-300 tons of India's opium may be diverted yearly. After estimating India's opiate consumption on the basis of UN-reported prevalence estimates, we find that diversion from licit production might have satisfied a quarter to more than a third of India's illicit opiate demand to 2004. India is not only among the world's largest consumer of illicit opiates but also one of the largest illicit opium producers. In contrast to all other illicit producers, India owes the latter distinction not to blatantly illicit cultivation but to diversion from licit cultivation. India's experience suggests the difficulty of preventing substantial leakage, even in a relatively well-governed nation.

Response of deep and shallow tropical maritime cumuli to large-scale processes

Science.gov (United States)

Yanai, M.; Chu, J.-H.; Stark, T. E.; Nitta, T.

1976-01-01

The bulk diagnostic method of Yanai et al. (1973) and a simplified version of the spectral diagnostic method of Nitta (1975) are used for a more quantitative evaluation of the response of various types of cumuliform clouds to large-scale processes, using the same data set in the Marshall Islands area for a 100-day period in 1956. The dependence of the cloud mass flux distribution on radiative cooling, large-scale vertical motion, and evaporation from the sea is examined. It is shown that typical radiative cooling rates in the tropics tend to produce a bimodal distribution of mass spectrum exhibiting deep and shallow clouds. The bimodal distribution is further enhanced when the large-scale vertical motion is upward, and a nearly unimodal distribution of shallow clouds prevails when the relative cooling is compensated by the heating due to the large-scale subsidence. Both deep and shallow clouds are modulated by large-scale disturbances. The primary role of surface evaporation is to maintain the moisture flux at the cloud base.

A simple process to achieve microchannels geometries able to produce hydrodynamic cavitation

Science.gov (United States)

Qiu, X.; Cherief, W.; Colombet, D.; Ayela, F.

2017-04-01

We present a simple process to perform microchannels in which cavitating two phase flows are easily producible. Up to now, hydrodynamic cavitation ‘on a chip’ was reached with small flow rates inside microchannels whose micromachining had involved a deep reactive ion etching (D-RIE). The process we present here does not require a D-RIE reactor, as it is only funded on a wet etching of silicon. It leads to a so-called microstep profile, and large cavitating flow rates become possible together with moderate pressure drops.

A simple process to achieve microchannels geometries able to produce hydrodynamic cavitation

International Nuclear Information System (INIS)

Qiu, X; Cherief, W; Colombet, D; Ayela, F

2017-01-01

We present a simple process to perform microchannels in which cavitating two phase flows are easily producible. Up to now, hydrodynamic cavitation ‘on a chip’ was reached with small flow rates inside microchannels whose micromachining had involved a deep reactive ion etching (D-RIE). The process we present here does not require a D-RIE reactor, as it is only funded on a wet etching of silicon. It leads to a so-called microstep profile, and large cavitating flow rates become possible together with moderate pressure drops. (technical note)

A new method of producing local enhancement of buoyancy in liquid flows

Science.gov (United States)

Bhat, G. S.; Narasimha, R.; Arakeri, V. H.

1989-11-01

We describe here a novel method of generating large volumetric heating in a liquid. The method uses the principle of ohmic heating of the liquid, rendered electrically conducting by suitable additives if necessary. Electrolysis is prevented by the use of high frequency alternating voltage and chemically treated electrodes. The technique is demonstrated by producing substantial heating in an initially neutral jet of water. Simple flow visualisation studies, made by adding dye to the jet, show marked changes in the growth and development of the jet with heat addition.

Recent Advances in Understanding Large Scale Vapour Explosions

International Nuclear Information System (INIS)

Board, S.J.; Hall, R.W.

1976-01-01

In foundries, violent explosions occur occasionally when molten metal comes into contact with water. If similar explosions can occur with other materials, hazardous situations may arise for example in LNG marine transportation accidents, or in liquid cooled reactor incidents when molten UO 2 contacts water or sodium coolant. Over the last 10 years a large body of experimental data has been obtained on the behaviour of small quantities of hot material in contact with a vaporisable coolant. Such experiments generally give low energy yields, despite producing fine fragmentation of the molten material. These events have been interpreted in terms of a wide range of phenomena such as violent boiling, liquid entrainment, bubble collapse, superheat, surface cracking and many others. Many of these studies have been aimed at understanding the small scale behaviour of the particular materials of interest. However, understanding the nature of the energetic events which were the original cause for concern may also be necessary to give confidence that violent events cannot occur for these materials in large scale situations. More recently, there has been a trend towards larger experiments and some of these have produced explosions of moderately high efficiency. Although occurrence of such large scale explosions can depend rather critically on initial conditions in a way which is not fully understood, there are signs that the interpretation of these events may be more straightforward than that of the single drop experiments. In the last two years several theoretical models for large scale explosions have appeared which attempt a self contained explanation of at least some stages of such high yield events: these have as their common feature a description of how a propagating breakdown of an initially quasi-stable distribution of materials is induced by the pressure and flow field caused by the energy release in adjacent regions. These models have led to the idea that for a full

Inhibiting effect of bioactive metabolites produced by mushroom cultivation on bacterial quorum sensing-regulated behaviors.

Science.gov (United States)

Zhu, Hu; Wang, Shou-Xian; Zhang, Shuai-Shuai; Cao, Chun-Xu

2011-01-01

This study aimed to search for novel quorum sensing (QS) inhibitors from mushroom and to analyze their inhibitory activity, with a view to their possible use in controlling detrimental infections. The bioactive metabolites produced by mushroom cultivation were tested for their abilities to inhibit QS-regulated behavior. All mushroom strains were cultivated in potato-dextrose medium by large-scale submerged fermentation. The culture supernatant was condensed into 0.2 vol by freeze-drying. The condensed supernatant was sterilized by filtration through a 0.22-μm membrane filter and added to Chromobacterium violaceum CV026 cultures, which were used to monitor QS inhibition. Inhibitory activity was measured by quantifying violacein production using a microplate reader. The results have revealed that, of 102 mushroom strains, the bioactive metabolites produced by 14 basidiomycetes were found to inhibit violacein production, a QS-regulated behavior in C. violaceum. Higher fungi can produce QS-inhibitory compounds. Copyright © 2011 S. Karger AG, Basel.

Secretome analysis of the thermophilic xylanase hyper-producer Thermomyces lanuginosus SSBP cultivated on corn cobs.

Science.gov (United States)

Winger, A M; Heazlewood, J L; Chan, L J G; Petzold, C J; Permaul, K; Singh, S

2014-11-01

Thermomyces lanuginosus is a thermophilic fungus known for its ability to produce industrially important enzymes including large amounts of xylanase, the key enzyme in hemicellulose hydrolysis. The secretome of T. lanuginosus SSBP was profiled by shotgun proteomics to elucidate important enzymes involved in hemicellulose saccharification and to characterise the presence of other industrially interesting enzymes. This study reproducibly identified a total of 74 proteins in the supernatant following growth on corn cobs. An analysis of proteins revealed nine glycoside hydrolase (GH) enzymes including xylanase GH11, β-xylosidase GH43, β-glucosidase GH3, α-galactosidase GH36 and trehalose hydrolase GH65. Two commercially produced Thermomyces enzymes, lipase and amylase, were also identified. In addition, other industrially relevant enzymes not currently explored in Thermomyces were identified including glutaminase, fructose-bisphosphate aldolase and cyanate hydratase. Overall, these data provide insight into the novel ability of a cellulase-free fungus to utilise lignocellulosic material, ultimately producing a number of enzymes important to various industrial processes.

Support of an Active Science Project by a Large Information System: Lessons for the EOS Era

Science.gov (United States)

Angelici, Gary L.; Skiles, J. W.; Popovici, Lidia Z.

1993-01-01

The ability of large information systems to support the changing data requirements of active science projects is being tested in a NASA collaborative study. This paper briefly profiles both the active science project and the large information system involved in this effort and offers some observations about the effectiveness of the project support. This is followed by lessons that are important for those participating in large information systems that need to support active science projects or that make available the valuable data produced by these projects. We learned in this work that it is difficult for a large information system focused on long term data management to satisfy the requirements of an on-going science project. For example, in order to provide the best service, it is important for all information system staff to keep focused on the needs and constraints of the scientists in the development of appropriate services. If the lessons learned in this and other science support experiences are not applied by those involved with large information systems of the EOS (Earth Observing System) era, then the final data products produced by future science projects may not be robust or of high quality, thereby making the conduct of the project science less efficacious and reducing the value of these unique suites of data for future research.

Process for producing ethanol from syngas

Science.gov (United States)

Krause, Theodore R; Rathke, Jerome W; Chen, Michael J

2013-05-14

The invention provides a method for producing ethanol, the method comprising establishing an atmosphere containing methanol forming catalyst and ethanol forming catalyst; injecting syngas into the atmosphere at a temperature and for a time sufficient to produce methanol; and contacting the produced methanol with additional syngas at a temperature and for a time sufficient to produce ethanol. The invention also provides an integrated system for producing methanol and ethanol from syngas, the system comprising an atmosphere isolated from the ambient environment; a first catalyst to produce methanol from syngas wherein the first catalyst resides in the atmosphere; a second catalyst to product ethanol from methanol and syngas, wherein the second catalyst resides in the atmosphere; a conduit for introducing syngas to the atmosphere; and a device for removing ethanol from the atmosphere. The exothermicity of the method and system obviates the need for input of additional heat from outside the atmosphere.

Titanium Matrix Composite Ti/TiN Produced by Diode Laser Gas Nitriding

Directory of Open Access Journals (Sweden)

Aleksander Lisiecki

2015-01-01

Full Text Available A high power direct diode laser, emitting in the range of near infrared radiation at wavelength 808–940 nm, was applied to produce a titanium matrix composite on a surface layer of titanium alloy Ti6Al4V by laser surface gas nitriding. The nitrided surface layers were produced as single stringer beads at different heat inputs, different scanning speeds, and different powers of laser beam. The influence of laser nitriding parameters on the quality, shape, and morphology of the surface layers was investigated. It was found that the nitrided surface layers consist of titanium nitride precipitations mainly in the form of dendrites embedded in the titanium alloy matrix. The titanium nitrides are produced as a result of the reaction between molten Ti and gaseous nitrogen. Solidification and subsequent growth of the TiN dendrites takes place to a large extent at the interface of the molten Ti and the nitrogen gas atmosphere. The direction of TiN dendrites growth is perpendicular to the surface of molten Ti. The roughness of the surface layers depends strongly on the heat input of laser nitriding and can be precisely controlled. In spite of high microhardness up to 2400 HV0.2, the surface layers are crack free.

Isolation and Characterization of a Double Stranded DNA Megavirus Infecting the Toxin-Producing Haptophyte Prymnesium parvum

Directory of Open Access Journals (Sweden)

Ben A. Wagstaff

2017-03-01

Full Text Available Prymnesium parvum is a toxin-producing haptophyte that causes harmful algal blooms globally, leading to large-scale fish kills that have severe ecological and economic implications. For the model haptophyte, Emiliania huxleyi, it has been shown that large dsDNA viruses play an important role in regulating blooms and therefore biogeochemical cycling, but much less work has been done looking at viruses that infect P. parvum, or the role that these viruses may play in regulating harmful algal blooms. In this study, we report the isolation and characterization of a lytic nucleo-cytoplasmic large DNA virus (NCLDV collected from the site of a harmful P. parvum bloom. In subsequent experiments, this virus was shown to infect cultures of Prymnesium sp. and showed phylogenetic similarity to the extended Megaviridae family of algal viruses.

BRILLIANT PEBBLES: A METHOD FOR DETECTION OF VERY LARGE INTERSTELLAR GRAINS

International Nuclear Information System (INIS)

Socrates, Aristotle; Draine, Bruce T.

2009-01-01

A photon of wavelength λ ∼ 1 μm interacting with a dust grain of radius a p ∼ 1 mm (a 'pebble') undergoes scattering in the forward direction, largely within a small characteristic diffraction angle θ s ∼ λ/a p ∼ 100''. Though millimeter-size dust grains contribute negligibly to the interstellar medium's visual extinction, the signal they produce in scattered light may be detectable, especially for variable sources. Observations of light scattered at small angles allow for the direct measurement of the large grain population; variable sources can also yield tomographic information of the interstellar medium's mass distribution. The ability to detect brilliant pebble halos requires a careful understanding of the instrument point-spread function.

Large deviations

CERN Document Server

Varadhan, S R S

2016-01-01

The theory of large deviations deals with rates at which probabilities of certain events decay as a natural parameter in the problem varies. This book, which is based on a graduate course on large deviations at the Courant Institute, focuses on three concrete sets of examples: (i) diffusions with small noise and the exit problem, (ii) large time behavior of Markov processes and their connection to the Feynman-Kac formula and the related large deviation behavior of the number of distinct sites visited by a random walk, and (iii) interacting particle systems, their scaling limits, and large deviations from their expected limits. For the most part the examples are worked out in detail, and in the process the subject of large deviations is developed. The book will give the reader a flavor of how large deviation theory can help in problems that are not posed directly in terms of large deviations. The reader is assumed to have some familiarity with probability, Markov processes, and interacting particle systems.

7 CFR 1212.19 - Producer.

Science.gov (United States)

2010-01-01

... producing, or causing to be produced, honey beyond personal use and having value at first point of sale. ... person who is engaged in the production and sale of honey in any State and who owns, or shares the...

Consumer's Fresh Produce Food Safety Practices: Outcomes of a Fresh Produce Safety Education Program

Science.gov (United States)

Scott, Amanda R.; Pope, Paul E.; Thompson, Britta M.

2009-01-01

The Centers for Disease Control and Prevention estimate that there are 76 million cases of foodborne disease annually. Foodborne disease is usually associated with beef, poultry, and seafood. However, there is an increasing number of foodborne disease cases related to fresh produce. Consumers may not associate fresh produce with foodborne disease…

Methods of producing cesium-131

Science.gov (United States)

Meikrantz, David H; Snyder, John R

2012-09-18

Methods of producing cesium-131. The method comprises dissolving at least one non-irradiated barium source in water or a nitric acid solution to produce a barium target solution. The barium target solution is irradiated with neutron radiation to produce cesium-131, which is removed from the barium target solution. The cesium-131 is complexed with a calixarene compound to separate the cesium-131 from the barium target solution. A liquid:liquid extraction device or extraction column is used to separate the cesium-131 from the barium target solution.

Studies on the propagation of relativistic plasma waves in high density plasmas produced by hypersonic ionizing shock waves

International Nuclear Information System (INIS)

Williams, R.L.; Johnson, J.A. III

1993-01-01

The feasibility of using an ionizing shock wave to produce high density plasmas suitable for the propagation large amplitude relativistic plasma waves is being investigated. A 20 kv arc driven shock tube of coaxial geometry produces a hypersonic shock wave (10 p > 10 17 cm -3 ). The shock can be made to reflect off the end of the tube, collide with its wake, and thus increase the plasma density further. After reflecting, the plasma is at rest. The shock speed is measured using piezoelectric pressure probes and the ion density is measured using laser induced fluorescence (LIF) techniques on argon 488.0 nm and 422.8 nm lines. The future plans are to excite large amplitude relativistic plasma waves in this plasma by either injecting a short pulse laser (Laser Wake Field Scheme), two beating lasers (Plasma Beat Wave Scheme), or a short bunch of relativistic electrons (Plasma Wake Field Scheme). Results of recent computational and theoretical studies, as well as initial experimental measurements on the plasma using LIF, are reported. Implications for the application of high density plasmas produced in this way to such novel schemes as the plasma wave accelerator, photon accelerator, plasma wave undulator, and also plasma lens, are discussed. The effect of plasma turbulence is also discussed

Progress on large superconducting toroidal field coils

International Nuclear Information System (INIS)

Haubenreich, P.N.; Luton, J.N.; Thompson, P.B.; Beard, D.S.

1979-01-01

Large superconducting toroidal field coils of competing designs are being produced by six major industrial teams. In the US, teams headed by General Dynamics Convair, General Electric, and Westinghouse are under contract to design and fabricate one coil each to specifications established by the Large Coil Program. A facility for testing 6 coils in a toroidal array at fields to 8 to 12 tesla is under construction at Oak Ridge. Through an international agreement, EURATOM, Japan, and Switzerland will produce one coil each for testing with the US coils. Each test coil will have a 2.5 x 3.5 m D-shape winding bore and is designed to operate at a current of 10 to 18 kA at a peak field of 8T while subjected to pulsed fields of 0.14 T applied in 1.0 s. There are significant differences among the six coil designs: five use NbTi, one Nb 3 Sn; three are cooled by pool boiling helium, three by forced flow; five have welded or bolted stainless steel coil cases, one has aluminum plate structure. All are designed to be cryostable at 8T, with structural margin for extended operation. The three US coil teams are almost or completely finished with detailed design and are now procuring materials and setting up manufacturing equipment. The non-US teams are at various stages of verification testing and design. The GDC and GE coils are scheduled for delivery in the spring of 1981 and the others will be completed a year later. The 11-m diameter vessel at the test facility has been completed and major components of the test stand are being procured. Engineering and procurement to upgrade the helium liquifier-refrigerator system are under way

Gold nanoparticles produced in a microalga

International Nuclear Information System (INIS)

Luangpipat, Tiyaporn; Beattie, Isabel R.; Chisti, Yusuf; Haverkamp, Richard G.

2011-01-01

An efficient biological route to production of gold nanoparticles which allows the nanoparticles to be easily recovered remains elusive. Live cells of the green microalga Chlorella vulgaris were incubated with a solution of gold chloride and harvested by centrifugation. Nanoparticles inside intact cells were identified by transmission electron microscopy and confirmed to be metallic gold by synchrotron based X-ray powder diffraction and X-ray absorption spectroscopy. These intracellular gold nanoparticles were 40–60 nm in diameter. At a concentration of 1.4% Au in the alga, a better than 97% recovery of the gold from solution was achieved. A maximum of 4.2% Au in the alga was obtained. Exposure of C. vulgaris to solutions containing dissolved salts of palladium, ruthenium, and rhodium also resulted in the production of the corresponding nanoparticles within the cells. These were surmised to be also metallic, but were produced at a much lower intracellular concentration than achieved with gold. Iridium was apparently toxic to the alga. No nanoparticles were observed using platinum solutions. C. vulgaris provides a possible route to large scale production of gold nanoparticles.

Agricultural Producer Certificates

Data.gov (United States)

Montgomery County of Maryland — A Certified Agricultural Producer, or representative thereof, is an individual who wishes to sell regionally-grown products in the public right-of-way. A Certified...

Microemulsion extrusion technique: a new method to produce lipid nanoparticles

Energy Technology Data Exchange (ETDEWEB)

Jesus, Marcelo Bispo de, E-mail: dejesusmb@gmail.com; Radaic, Allan [University of Campinas-UNICAMP, Department of Biochemistry, Institute of Biology (Brazil); Zuhorn, Inge S. [University of Groningen, Department of Membrane Cell Biology, University Medical Center (Netherlands); Paula, Eneida de [University of Campinas-UNICAMP, Department of Biochemistry, Institute of Biology (Brazil)

2013-10-15

Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) have been intensively investigated for different applications, including their use as drug and gene delivery systems. Different techniques have been employed to produce lipid nanoparticles, of which high pressure homogenization is the standard technique that is adopted nowadays. Although this method has a high efficiency, does not require the use of organic solvents, and allows large-scale production, some limitations impede its application at laboratory scale: the equipment is expensive, there is a need of huge amounts of surfactants and co-surfactants during the preparation, and the operating conditions are energy intensive. Here, we present the microemulsion extrusion technique as an alternative method to prepare lipid nanoparticles. The parameters to produce lipid nanoparticles using microemulsion extrusion were established, and the lipid particles produced (SLN, NLC, and liposomes) were characterized with regard to size (from 130 to 190 nm), zeta potential, and drug (mitoxantrone) and gene (pDNA) delivery properties. In addition, the particles' in vitro co-delivery capacity (to carry mitoxantrone plus pDNA encoding the phosphatase and tensin homologue, PTEN) was tested in normal (BALB 3T3 fibroblast) and cancer (PC3 prostate and MCF-7 breast) cell lines. The results show that the microemulsion extrusion technique is fast, inexpensive, reproducible, free of organic solvents, and suitable for small volume preparations of lipid nanoparticles. Its application is particularly interesting when using rare and/or costly drugs or ingredients (e.g., cationic lipids for gene delivery or labeled lipids for nanoparticle tracking/diagnosis)

Microemulsion extrusion technique: a new method to produce lipid nanoparticles

International Nuclear Information System (INIS)

Jesus, Marcelo Bispo de; Radaic, Allan; Zuhorn, Inge S.; Paula, Eneida de

2013-01-01

Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) have been intensively investigated for different applications, including their use as drug and gene delivery systems. Different techniques have been employed to produce lipid nanoparticles, of which high pressure homogenization is the standard technique that is adopted nowadays. Although this method has a high efficiency, does not require the use of organic solvents, and allows large-scale production, some limitations impede its application at laboratory scale: the equipment is expensive, there is a need of huge amounts of surfactants and co-surfactants during the preparation, and the operating conditions are energy intensive. Here, we present the microemulsion extrusion technique as an alternative method to prepare lipid nanoparticles. The parameters to produce lipid nanoparticles using microemulsion extrusion were established, and the lipid particles produced (SLN, NLC, and liposomes) were characterized with regard to size (from 130 to 190 nm), zeta potential, and drug (mitoxantrone) and gene (pDNA) delivery properties. In addition, the particles’ in vitro co-delivery capacity (to carry mitoxantrone plus pDNA encoding the phosphatase and tensin homologue, PTEN) was tested in normal (BALB 3T3 fibroblast) and cancer (PC3 prostate and MCF-7 breast) cell lines. The results show that the microemulsion extrusion technique is fast, inexpensive, reproducible, free of organic solvents, and suitable for small volume preparations of lipid nanoparticles. Its application is particularly interesting when using rare and/or costly drugs or ingredients (e.g., cationic lipids for gene delivery or labeled lipids for nanoparticle tracking/diagnosis)

The German Market for photovoltaic (solar-produced electricity)

International Nuclear Information System (INIS)

1999-06-01

In preparation for reducing the CO2 emission and in so living up to the Kyoto-protocol with the succeeding changes, renewable energy has - including photovoltaic - got an increasing importance in the world over - especially in Germany. If the technical potentials in Germany are utilized optimally, then 75% of the total German electricity production with photovoltaic are covered. At the moment it is only about 1 per thousand. There is a political will to promote photovoltaic in Germany, which results in high account prices and different plant supporting programmes. In the coming 6 years the official aim is that a minimum of 100.000 photovoltaic power plants are installed with an average capacitate for 3 kWp. The competition for the market is hard. There are many national and international suppliers, so the co-operations between the large German producers seem to be obvious. (EHS)

Thyrotropin-producing adenoma. Report of two clinical cases

Directory of Open Access Journals (Sweden)

Ani R. Karapetyan

2017-03-01

Full Text Available Diagnosis of hyperthyroidism does not present serious difficulties currently. Distribution of imaging techniques increasing the detection of pituitary adenomas every year. Thyrotropin-producing adenoma is a rare cause of hyperthyroidism. Early detection will alert its errors in treatment strategy, unjustified surgery on the thyroid gland, and will improve the quality of patients life. The article presents two clinical cases of thyroid-stimulating hormone (TSH-secreting pituitary adenomas in patients with different disease duration, and thus the presence of hyperthyroidism complications. Both patients were operated in the Federal Center of Neurosurgery Novosibirsk by transnasal transsphenoidal approach. The resistant euthyroidism was reached postoperatively, but in patients with long-term history of the disease, large size of adenoma in the postoperative period developed secondary adrenal insufficiency and her quality of life is significantly lower, taking into account comorbidities. The period of follow-up consists 3 years and one year respectively.

29 CFR 780.213 - Produce business.

Science.gov (United States)

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Produce business. 780.213 Section 780.213 Labor Regulations... Specific Situations Hatchery Operations § 780.213 Produce business. In some instances, hatcheries also engage in the produce business as such and commingle with the culled eggs and chickens other eggs and...

A method of producing hydroxymethyfurfural

DEFF Research Database (Denmark)

2011-01-01

The present invention relates to a method of producing 5-hydroxymethylfurfural by dehydration of fructose and/or glucose and/or mannose.......The present invention relates to a method of producing 5-hydroxymethylfurfural by dehydration of fructose and/or glucose and/or mannose....

A Novel Method of Fabricating Flexible Transparent Conductive Large Area Graphene Film

International Nuclear Information System (INIS)

Fan Tian-Ju; Yuan Chun-Qiu; Tang Wei; Tong Song-Zhao; Huang Wei; Min Yong-Gang; Liu Yi-Dong; Epstein, Arthur J.

2015-01-01

We fabricate flexible conductive and transparent graphene films on position-emission-tomography substrates and prepare large area graphene films by graphite oxide sheets with the new technical process. The multi-layer graphene oxide sheets can be chemically reduced by HNO 3 and HI to form a highly conductive graphene film on a substrate at lower temperature. The reduced graphene oxide sheets show a high conductivity sheet with resistance of 476 Ω/sq and transmittance of 76% at 550 nm (6 layers). The technique used to produce the transparent conductive graphene thin film is facile, inexpensive, and can be tunable for a large area production applied for electronics or touch screens. (paper)

Monotop phenomenology at the Large Hadron Collider

CERN Document Server

Agram, Jean-Laurent; Buttignol, Michael; Conte, Eric; Fuks, Benjamin

2014-01-01

We investigate new physics scenarios where systems comprised of a single top quark accompanied by missing transverse energy, dubbed monotops, can be produced at the LHC. Following a simplified model approach, we describe all possible monotop production modes via an effective theory and estimate the sensitivity of the LHC, assuming 20 fb$^{-1}$ of collisions at a center-of-mass energy of 8 TeV, to the observation of a monotop state. Considering both leptonic and hadronic top quark decays, we show that large fractions of the parameter space are reachable and that new physics particles with masses ranging up to 1.5 TeV can leave hints within the 2012 LHC dataset, assuming moderate new physics coupling strengths.

7 CFR 1033.13 - Producer milk.

Science.gov (United States)

2010-01-01

... Handling Definitions § 1033.13 Producer milk. Producer milk means the skim milk (or the skim equivalent of components of skim milk), including nonfat components, and butterfat in milk of a producer that is: (a... percentages in paragraph (d)(4) of this section may be increased or decreased by the market administrator if...

7 CFR 1001.13 - Producer milk.

Science.gov (United States)

2010-01-01

... Handling Definitions § 1001.13 Producer milk. Producer milk means the skim milk (or the skim equivalent of components of skim milk) and butterfat contained in milk of a producer that is: (a) Received by the operator... be increased or decreased by the Market Administrator if the Market Administrator finds that such...

7 CFR 1126.13 - Producer milk.

Science.gov (United States)

2010-01-01

... Handling Definitions § 1126.13 Producer milk. Producer milk means the skim milk (or the skim equivalent of components of skim milk), including nonfat components, and butterfat contained in milk of a producer that is...) of this section may be increased or decreased by the market administrator if there is a finding that...

Large quantity production of carbon and boron nitride nanotubes by mechano-thermal process

International Nuclear Information System (INIS)

Chen, Y.; Fitzgerald, J.D.; Chadderton, L.; Williams, J.S.; Campbell, S.J.

2002-01-01

Full text: Nanotube materials including carbon and boron nitride have excellent properties compared with bulk materials. The seamless graphene cylinders with a high length to diameter ratio make them as superstrong fibers. A high amount of hydrogen can be stored into nanotubes as future clean fuel source. Theses applications require large quantity of nanotubes materials. However, nanotube production in large quantity, fully controlled quality and low costs remains challenges for most popular synthesis methods such as arc discharge, laser heating and catalytic chemical decomposition. Discovery of new synthesis methods is still crucial for future industrial application. The new low-temperature mechano-thermal process discovered by the current author provides an opportunity to develop a commercial method for bulk production. This mechano-thermal process consists of a mechanical ball milling and a thermal annealing processes. Using this method, both carbon and boron nitride nanotubes were produced. I will present the mechano-thermal method as the new bulk production technique in the conference. The lecture will summarise main results obtained. In the case of carbon nanotubes, different nanosized structures including multi-walled nanotubes, nanocells, and nanoparticles have been produced in a graphite sample using a mechano-thermal process, consisting of I mechanical milling at room temperature for up to 150 hours and subsequent thermal annealing at 1400 deg C. Metal particles have played an important catalytic effect on the formation of different tubular structures. While defect structure of the milled graphite appears to be responsible for the formation of small tubes. It is found that the mechanical treatment of graphite powder produces a disordered and microporous structure, which provides nucleation sites for nanotubes as well as free carbon atoms. Multiwalled carbon nanotubes appear to grow via growth of the (002) layers during thermal annealing. In the case of BN

Research on the Technology of Producing Building Stone by Using Blast Furnace Slag

Science.gov (United States)

Yan, Bingji; Zhang, Jianliang; Guo, Hongwei; Shi, Zhiwen; Liu, Feng

During production of a large quantity of steel, slag is produced at the same time. This paper chooses blast furnace slag (BFS) as the main material for the research. The purpose of the research is to explore its optimal physicochemical properties and the use of BFS in building stone field. The paper elaborates the experimentation process of producing glass-ceramics and presents the results. The results show that SiO2 content in BFS and amount of Cr2O3 and Fe2O3 added as nucleating agents have certain effect on the properties of glass-ceramics. The results also show that the exothermic peak temperature of base glass is the lowest when adding 20% SiO2 to the BFS, and 2% Cr2O3 and 3% Fe2O3 as nucleating agents, which makes easy crystallization and optimal properties of the glass-ceramics.

Simultaneous thigh muscle metastasis from lung cancer and Escherichia coli gas producing myonecrosis

International Nuclear Information System (INIS)

Martinez, Gonzalo E.; Coursey, Courtney A.; Martinez, Salutario; Dodd, Leslie

2008-01-01

We present the case of a 41-year-old man with known large cell lung cancer who had undergone left pneumonectomy 7 months prior and who presented with a large intramuscular mass involving the posterior left thigh and upper calf. This thigh mass was ultimately surgically explored, and specimens yielded both Escherichia coli organisms and cells reflecting a skeletal muscle metastasis from the patient's known lung cancer. The patient was also found to have a rectal metastasis from his lung cancer. Intramuscular abscesses produced by gastrointestinal tract flora are a well-known presentation of colon cancer. To our knowledge, this is the first case report of the simultaneous occurrence of a skeletal muscle metastasis and an E. coli abscess in the same anatomic location. We believe the patient's rectal metastasis may have been the intermediate step in this process. (orig.)

Producers' Complex Risk Management Choices

NARCIS (Netherlands)

Pennings, J.M.E.; Isengildina, O.; Irwin, S.H.; Garcia, P.; Good, D.L.

2008-01-01

Producers have a wide variety of risk management instruments available, making their choice(s) complex. The way producers deal with this complexity can vary and may influence the impact that the determinants, such as risk aversion, have on their choices. A recently developed choice bracketing

A document preparation system in a large network environment

Energy Technology Data Exchange (ETDEWEB)

Vigil, M.; Bouchier, S.; Sanders, C.; Sydoriak, S.; Wheeler, K.

1988-01-01

At Los Alamos National Laboratory, we have developed an integrated document preparation system that produces publication-quality documents. This system combines text formatters and computer graphics capabilities that have been adapted to meet the needs of users in a large scientific research laboratory. This paper describes the integration of document processing technology to develop a system architecture, based on a page description language, to provide network-wide capabilities in a distributed computing environment. We describe the Laboratory requirements, the integration and implementation issues, and the challenges we faced developing this system.

Chemical hole doping into large-area transition metal dichalcogenide monolayers using boron-based oxidant

KAUST Repository

Matsuoka, Hirofumi; Kanahashi, Kaito; Tanaka, Naoki; Shoji, Yoshiaki; Li, Lain-Jong; Pu, Jiang; Ito, Hiroshi; Ohta, Hiromichi; Fukushima, Takanori; Takenobu, Taishi

2018-01-01

Hole carrier doping into single-crystalline transition metal dichalcogenide (TMDC) films can be achieved with various chemical reagents. However, large-area polycrystalline TMDC monolayers produced by a chemical vapor deposition (CVD) growth method have yet to be chemically doped. Here, we report that a salt of a two-coordinate boron cation, Mes2B+ (Mes: 2,4,6-trimethylphenyl group), with a chemically stable tetrakis(pentafluorophenyl)borate anion, [(C6F5)4B]−, can serve as an efficient hole-doping reagent for large-area CVD-grown tungsten diselenide (WSe2) films. Upon doping, the sheet resistance of large-area polycrystalline WSe2 monolayers decreased from 90 GΩ/sq to 3.2 kΩ/sq.

Chemical hole doping into large-area transition metal dichalcogenide monolayers using boron-based oxidant

KAUST Repository

Matsuoka, Hirofumi

2018-01-18

Hole carrier doping into single-crystalline transition metal dichalcogenide (TMDC) films can be achieved with various chemical reagents. However, large-area polycrystalline TMDC monolayers produced by a chemical vapor deposition (CVD) growth method have yet to be chemically doped. Here, we report that a salt of a two-coordinate boron cation, Mes2B+ (Mes: 2,4,6-trimethylphenyl group), with a chemically stable tetrakis(pentafluorophenyl)borate anion, [(C6F5)4B]−, can serve as an efficient hole-doping reagent for large-area CVD-grown tungsten diselenide (WSe2) films. Upon doping, the sheet resistance of large-area polycrystalline WSe2 monolayers decreased from 90 GΩ/sq to 3.2 kΩ/sq.

Producing colour pictures from SCAN

International Nuclear Information System (INIS)

Robichaud, K.

1982-01-01

The computer code SCAN.TSK has been written for use on the Interdata 7/32 minicomputer which will convert the pictures produced by the SCAN program into colour pictures on a colour graphics VDU. These colour pictures are a more powerful aid to detecting errors in the MONK input data than the normal lineprinter pictures. This report is intended as a user manual for using the program on the Interdata 7/32, and describes the method used to produce the pictures and gives examples of JCL, input data and of the pictures that can be produced. (U.K.)

Producing new radionuclides for medicine

International Nuclear Information System (INIS)

Michaut, C.

2009-01-01

The Arronax cyclotron, a new particle accelerator dedicated to the production of radionuclides for medicine and research has been commissioned in Nantes (France). Because of its unique features: an energy of 70 MeV and an intensity of 750 μA, Arronax will produce radionuclides that can not be produce in present cyclotrons. Among others it will produce Strontium-82 and Germanium-68 that are the precursors for Rubidium-82 and Gallium-68 respectively. 20 per cent of the research works will be dedicated to other domains like radioactive wastes, the radiation biological damage and the radiation damage on electronic devices. (A.C.)

Relation between the petrographic composition of coal and the morphology of pyrolysis char produced in fluidized bed

Energy Technology Data Exchange (ETDEWEB)

B. Valentim; M.J. Lemos de Sousa; P. Abelha; D. Boavida; I. Gulyurtlu [Centro de Geologia da Universidade do Porto, Porto (Portugal)

2004-06-01

Several previous studies have already established, for pulverized coal combustion conditions, global correlations between petrographic composition of the coal and those of char produced from the same coal. However, for fluidized bed combustion, there has not been much new work since the eighties. The results presented in this paper include the petrographic characterization of seven different coals from several origins and also of their respective chars produced at 700, 800, 900, and 1000{sup o}C in a laboratory fluidized bed reactor. The results show a marked predominance of tenuispheres as the trial temperatures increase. While vitrinite-rich coals essentially produced highly porous chars, the inertinite-rich coals produced large amounts of medium- and low-porous chars. Semi-anthracite vitrinite produced high-porous chars and thermal affected coal particles originated low-porous and angular char morphotypes. The analysis of the data obtained revealed that vitrinite + liptinite related well with the high-porous char (sum of cenospheres and tenuinetworks), classified as Group 1. The same trend, but with a weaker relation, was also observed between vitrinite and liptinite rich microlithotypes and Group 1. 32 refs., 17 refs., 3 tabs.

7 CFR 1006.13 - Producer milk.

Science.gov (United States)

2010-01-01

... Handling Definitions § 1006.13 Producer milk. Producer milk means the skim milk (or the skim equivalent of components of skim milk) and butterfat contained in milk of a producer that is: (a) Received by the operator... (d) (1) through (3) of this section may be increased or decreased by the market administrator if the...

Projected large flood event sensitivity to projection selection and temporal downscaling methodology

Energy Technology Data Exchange (ETDEWEB)

Raff, D. [U.S. Dept. of the Interior, Bureau of Reclamation, Denver, Colorado (United States)

2008-07-01

Large flood events, that influence regulatory guidelines as well as safety of dams decisions, are likely to be affected by climate change. This talk will evaluate the use of climate projections downscaled and run through a rainfall - runoff model and its influence on large flood events. The climate spatial downscaling is performed statistically and a re-sampling and scaling methodology is used to temporally downscale from monthly to daily signals. The signals are run through a National Weather Service operational rainfall-runoff model to produce 6-hour flows. The flows will be evaluated for changes in large events at look-ahead horizons from 2011 - 2040, 2041 - 2070, and 2071 - 2099. The sensitivity of results will be evaluated with respect to projection selection criteria and re-sampling and scaling criteria for the Boise River in Idaho near Lucky Peak Dam. (author)

Projected large flood event sensitivity to projection selection and temporal downscaling methodology

International Nuclear Information System (INIS)

Raff, D.

2008-01-01

Large flood events, that influence regulatory guidelines as well as safety of dams decisions, are likely to be affected by climate change. This talk will evaluate the use of climate projections downscaled and run through a rainfall - runoff model and its influence on large flood events. The climate spatial downscaling is performed statistically and a re-sampling and scaling methodology is used to temporally downscale from monthly to daily signals. The signals are run through a National Weather Service operational rainfall-runoff model to produce 6-hour flows. The flows will be evaluated for changes in large events at look-ahead horizons from 2011 - 2040, 2041 - 2070, and 2071 - 2099. The sensitivity of results will be evaluated with respect to projection selection criteria and re-sampling and scaling criteria for the Boise River in Idaho near Lucky Peak Dam. (author)

The large binocular telescope.

Science.gov (United States)

Hill, John M

2010-06-01

The Large Binocular Telescope (LBT) Observatory is a collaboration among institutions in Arizona, Germany, Italy, Indiana, Minnesota, Ohio, and Virginia. The telescope on Mount Graham in Southeastern Arizona uses two 8.4 m diameter primary mirrors mounted side by side. A unique feature of the LBT is that the light from the two Gregorian telescope sides can be combined to produce phased-array imaging of an extended field. This cophased imaging along with adaptive optics gives the telescope the diffraction-limited resolution of a 22.65 m aperture and a collecting area equivalent to an 11.8 m circular aperture. This paper describes the design, construction, and commissioning of this unique telescope. We report some sample astronomical results with the prime focus cameras. We comment on some of the technical challenges and solutions. The telescope uses two F/15 adaptive secondaries to correct atmospheric turbulence. The first of these adaptive mirrors has completed final system testing in Firenze, Italy, and is planned to be at the telescope by Spring 2010.

Behavioral and physiological changes produced by a supralethal dose of ionizing radiation: evidence for hormone-influenced sex differences in the rat

International Nuclear Information System (INIS)

Mickley, G.A.

1980-01-01

A sufficiently large and rapid dose of ionizing radiation produces an immediate but transient behavioral incapacitation. Acute hypotension often accompanies the disorder. Although the etiology of this syndrome is unclear, it has been suggested that an increase in histamine excretion contributes to it. Since histamine is known to interact with the endocrine system and since estrogens have been shown to prolong the life of animals exposed to potentially lethal doses of radiation, it was also hypothesized that females might be relatively less affected by an acute, large dose of ionizing radiation. Male and female rats were trained on an avoidance task, irradiated, and then retested. Females showed a less severe decrement after radiation exposure than males. Likewise, females did not suffer the severe hypotension normally associated with male radiogenic early transient incapacitation (ETI); rather, an acute hypertension was produced in females. A second series of experiments revealed that differences in male and female radiation response were eliminated by gonadectomy. Systemic estradiol injection produced strikingly feminine (i.e., superior) postirradiation avoidance responses as well as hypertension in neutered rats. Testosterone injections had no effect on either measure. Central nervous system alterations have been correlated with the ETI. Therefore, final experiments sought a possible central locus of the action of estradiol. It was found that exposure of the nucleus peopticus medialis to estrogens produces postirradiation benefits in avoidance performance and blood pressure similar to those seen after systemic estradiol treatments. Nucleus amygdaloideus medialis implants produced no such benefits

Improved Monkey-King Genetic Algorithm for Solving Large Winner Determination in Combinatorial Auction

Science.gov (United States)

Li, Yuzhong

Using GA solve the winner determination problem (WDP) with large bids and items, run under different distribution, because the search space is large, constraint complex and it may easy to produce infeasible solution, would affect the efficiency and quality of algorithm. This paper present improved MKGA, including three operator: preprocessing, insert bid and exchange recombination, and use Monkey-king elite preservation strategy. Experimental results show that improved MKGA is better than SGA in population size and computation. The problem that traditional branch and bound algorithm hard to solve, improved MKGA can solve and achieve better effect.

Polishing large NaCl windows on a continuous polisher

International Nuclear Information System (INIS)

Williamson, R.

1979-01-01

The Helios and Antares CO 2 fusion laser systems incorporate numerous large sodium chloride windows. These must be refinished periodically, making necessary a consistent and predictable polishing capability. A continuous polisher (or annular lap) which might at Kirtland's Developmental Optical Facility. Large NaCl windows had not been polished on this type of machine. The machine has proven itself capable of producing lambda/16 figures at 633 nm (HeNe) with extremely smooth surfaces on glass. Since then, we have been working exclusively on NaCl optics. Due to different polishing parameters between NaCl and glass, and the slight solubility of the pitch in the slurry, this phase presents new problems. The work on glass will be reviewed. Results on NaCl to date will be reported. The potential of this type of machine relative to prisms, thin and irregularly shaped optics will be discussed

W/Cu composites produced by low temperature Pulse Plasma Sintering

International Nuclear Information System (INIS)

Rosinski, M.S.; Fortuna, E.; Michalski, A.J.; Kurzydlowski, K.J.

2006-01-01

The plasma facing components (PFCs) must withstand the thermal, mechanical and neutron loads under cyclic mode of operation and vacuum. Despite that PFCs of ITER and demonstration reactors must assure reliability and long in service lifetime. For that reason PFCs are designed to be made of beryllium, tungsten or carbon fibre composites armours and copper based heat sink material. Such design concepts can only be used if joining methods of these dissimilar materials are resolved. Several techniques have been developed for joining W and Cu e. g. casting of pure Cu onto W, high temperature brazing, direct diffusion bonding or CVDs of W onto Cu. The main problem in the development of such joints is the large difference in the coefficients of thermal expansion, CTE (alpha Cu > 4 alpha W) and elastic modula (ECu > 0.2 EW). These differences result in large stresses at the W/Cu interfaces during manufacturing and/or during operation, which may lead to cracking or delamination reducing lifetime of the components. Possible solution to this problem is the use of W-Cu composites (FGM). W-Cu composites are widely used for spark erosion electrodes, in heavy duty circuit breakers and as heat sinks of microelectronic devices. They are commonly produced by infiltration of a porous sintered tungsten by liquid copper. Other technological route is powder metallurgy. Coatings can be produced by low pressure plasma spraying. All these methods, however, are known to have some disadvantages. For infiltration there is a 30 wt.% limit of Cu content while for powder metallurgy and plasma spraying techniques porosity is of concern. In our work the W-Cu composites of different composition were produced by pulse plasma sintering (PPS). This new method utilizes pulsed high electric discharges to heat the powders under uniaxial load. The arc discharges clean surface of powder particles and intensify diffusion. The total sintering time is reduced to several minutes. In our investigations various

7 CFR 1205.319 - Cotton-producing region.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Cotton-producing region. 1205.319 Section 1205.319... Cotton Research and Promotion Order Definitions § 1205.319 Cotton-producing region. Cotton-producing region means each of the following groups of cotton-producing States: (a) Southeast Region: Alabama...

U.K., Norway producers push gas exports to mainland Europe

International Nuclear Information System (INIS)

Anon.

1992-01-01

This paper reports that producers in Norway and the U.K. are moving toward their goals of increasing natural gas exports to mainland Europe. Troll and Sleipner fields on the Norwegian continental shelf, along with the Zeepipe and Europipe lines linking Norway with mid-Europe, are the main building blocks of the Troll gas sales agreement, the foundation for Norway's plans. Total investment will exceed $11 billion. The Troll agreement involves about 28 billion cu m of gas and is currently the subject of negotiations between Troll field partners and the buyers. In 1986, when the contract was first agreed, it was a buyer's market. Increasing demand in the last 2 years has changed that. Also, new taxes on gas and oil products have driven both parties back to the negotiating table. Adjustments cane be called for every 3 years under the Troll contract; this is the first time parties have invoked the provision. Torstein Indrebo of Norsk Hydro says the contract gas price is based on prices of competing energy sources, such as oil, coal fired electricity, and nuclear power. Because volumes are so large, he says, small adjustments in the gas price have a large effect

7 CFR 1131.13 - Producer milk.

Science.gov (United States)

2010-01-01

... Handling Definitions § 1131.13 Producer milk. Producer milk means the skim milk (or the skim equivalent of components of skim milk) and butterfat in milk of a producer that is: (a) Received by the operator of a pool... percentage in paragraph (d)(2) of this section may be increased or decreased by the market administrator if...

Production of a large area diffuse arc plasma with multiple cathode

International Nuclear Information System (INIS)

Wang Cheng; Cui Hai-Chao; Li Wan-Wan; Liao Meng-Ran; Xia Wei-Dong; Xia Wei-Luo

2017-01-01

An arc channel at atmospheric pressure tends to shrink generally. In this paper, a non-transferred DC arc plasma device with multiple cathode is introduced to produce a large area arc plasma at atmospheric pressure. This device is comprised of a 42-mm diameter tubular chamber, multiple cathode which is radially inserted into the chamber, and a tungsten anode with a nozzle in its center. In argon/helium atmosphere, a large area and circumferential homogenous diffuse arc plasma, which fills the entire cross section surrounded by the cathode tips, is observed. Results show that the uniformity and stability of diffuse arc plasma are strongly related to the plasma forming gas. Based on these experimental results, an explanation to the arc diffusion is suggested. Moreover, the electron excitation temperature and electron density measured in diffuse helium plasma are much lower than those of constricted arc column, which indicates the diffuse helium plasma probably deviates from the local thermodynamic equilibrium state. Unlike the common non-transferred arc plasma devices, this device can provide a condition for axial-fed feedstock particles. The plasma device is attempted to spheroidize alumina powders by using the central axis to send the powder. Results show that the powder produced is usually a typical hollow sphere. (paper)

7 CFR 760.303 - Eligible livestock producer.

Science.gov (United States)

2010-01-01

... 7 Agriculture 7 2010-01-01 2010-01-01 false Eligible livestock producer. 760.303 Section 760.303... AGRICULTURE SPECIAL PROGRAMS INDEMNITY PAYMENT PROGRAMS Livestock Forage Disaster Program § 760.303 Eligible livestock producer. (a) To be considered an eligible livestock producer, the eligible producer on a farm...

Apparatus and method for large tunnel excavation in hard rock

International Nuclear Information System (INIS)

Altseimer, J.H.; Hanold, R.J.

1975-01-01

A tunneling machine is described for producing large tunnels in rock by progressive detachment of the tunnel core by thermal melting a boundary kerf into the tunnel face and simultaneously forming an initial tunnel wall support by deflecting the molten materials against the tunnel walls to provide, when solidified, a continuous liner; and fragmenting the tunnel core circumscribed by the kerf by thermal stress fracturing and in which the heat required for such operations is supplied by a compact nuclear reactor. (U.S.)

A Combined Eulerian-Lagrangian Data Representation for Large-Scale Applications.

Science.gov (United States)

Sauer, Franz; Xie, Jinrong; Ma, Kwan-Liu

2017-10-01

The Eulerian and Lagrangian reference frames each provide a unique perspective when studying and visualizing results from scientific systems. As a result, many large-scale simulations produce data in both formats, and analysis tasks that simultaneously utilize information from both representations are becoming increasingly popular. However, due to their fundamentally different nature, drawing correlations between these data formats is a computationally difficult task, especially in a large-scale setting. In this work, we present a new data representation which combines both reference frames into a joint Eulerian-Lagrangian format. By reorganizing Lagrangian information according to the Eulerian simulation grid into a "unit cell" based approach, we can provide an efficient out-of-core means of sampling, querying, and operating with both representations simultaneously. We also extend this design to generate multi-resolution subsets of the full data to suit the viewer's needs and provide a fast flow-aware trajectory construction scheme. We demonstrate the effectiveness of our method using three large-scale real world scientific datasets and provide insight into the types of performance gains that can be achieved.

The world's largest LNG producer's next market

International Nuclear Information System (INIS)

Fuller, R.; Isworo Suharno; Simandjuntak, W.M.P.

1996-01-01

The development of the domestic gas market in Indonesia, the world's largest liquefied natural gas producing country, is described as part of the overall impact of the country's oil and gas production. The first large scale use of natural gas in Indonesia was established in 1968 when a fertiliser plant using gas as the feedstock was built. Ultimately, through increased yields, this has enabled Indonesia to be self-sufficient in rice and an exporter of fertiliser. Problems which stand in the way of further developments include: capital, though Pertamina and PGN are perceived as attractive for foreign investment; the lack of a regulatory framework for gas; geographical constraints, among them the fact that the gas deposits are remote from the largest population concentrations; lack of infrastructure. There are nevertheless plans for expansion and the provision of an integrated gas pipeline system. Pertamina, which has responsibility for all oil and gas developments, and PGN, whose primary role has been as a manufacturer and distributor of gas, are now working together in the coordination of all gas activities. (10 figures). (UK)

Taking Energy to the Physics Classroom from the Large Hadron Collider at CERN

Science.gov (United States)

Cid, Xabier; Cid, Ramon

2009-01-01

In 2008, the greatest experiment in history began. When in full operation, the Large Hadron Collider (LHC) at CERN will generate the greatest amount of information that has ever been produced in an experiment before. It will also reveal some of the most fundamental secrets of nature. Despite the enormous amount of information available on this…

Analysis of potential fumonisin-producing Fusarium species in corn products from three main maize-producing areas in eastern China.

Science.gov (United States)

Zhang, Liping; Wang, Jiansheng; Zhang, Chulong; Wang, Qiaomei

2013-02-01

Fusarium species are common fungal contaminants of maize and a number of them can produce mycotoxin fumonisins. China is one of the largest maize producers in the world. This study investigated the contamination of maize samples from three areas in eastern China by Fusarium and fumonisin-producing fungi as well as their fumonisin-producing potential. A total of 22 Fusarium strains were isolated, 19 of which were able to produce fumonisin. Among the 19 strains, 16 belonged to F. verticillioides, two to F. subglutinans and one to F. proliferatum. The majority (17/19) of the fumonisin-forming strains were high FB(1) producers, which is a potential health risk for the population in these areas. Fusarium contamination in samples from the mideastern area was the most serious (11 Fusarium strains, with nine producing fumonisin, isolated from 24 samples), followed by the northeastern area (nine Fusarium strains, with all nine producing fumonisin, isolated from 21 samples) and the southeastern area (two Fusarium strains, with one producing fumonisin, isolated from 19 samples). Although the overall levels of FBs and contamination by fumonisin-producing fungi in corn samples were not serious, the contaminating Fusarium strains possessed fairly strong toxicogenic ability and potential risk for food safety. Copyright © 2012 Society of Chemical Industry.

76 FR 33969 - Marketing Order Regulating the Handling of Spearmint Oil Produced in the Far West; Revision of...

Science.gov (United States)

2011-06-10

... the allotment percentage from 43 percent to 50 percent. This change is expected to balance the supply... cultural practice in the production of spearmint oil for weed, insect, and disease control. To remain... farms fall into the SBA category of large businesses. Small spearmint oil producers generally are not as...

Hypersingular integral equations, waveguiding effects in Cantorian Universe and genesis of large scale structures

International Nuclear Information System (INIS)

Iovane, G.; Giordano, P.

2005-01-01

In this work we introduce the hypersingular integral equations and analyze a realistic model of gravitational waveguides on a cantorian space-time. A waveguiding effect is considered with respect to the large scale structure of the Universe, where the structure formation appears as if it were a classically self-similar random process at all astrophysical scales. The result is that it seems we live in an El Naschie's o (∞) Cantorian space-time, where gravitational lensing and waveguiding effects can explain the appearing Universe. In particular, we consider filamentary and planar large scale structures as possible refraction channels for electromagnetic radiation coming from cosmological structures. From this vision the Universe appears like a large self-similar adaptive mirrors set, thanks to three numerical simulations. Consequently, an infinite Universe is just an optical illusion that is produced by mirroring effects connected with the large scale structure of a finite and not a large Universe

Potential of volatile compounds produced by fungi to influence sensory quality of coffee beverage

DEFF Research Database (Denmark)

Iamanaka, B. T.; Teixeira, A. A.; Teixeira, A. R. R.

2014-01-01

Fungi are known producers of a large number of volatile compounds (VCs). Several VCs such as 2,4,6 trichloroanisole (TCA), geosmin and terpenes have been found in coffee beverages, and these compounds can be responsible for off-flavor development. However, few studies have related the fungal...... contamination of coffee with the sensory characteristics of the beverage. The aim of this research was to investigate the production of VCs by fungi isolated from coffee and their potential as modifiers of the sensory coffee beverage quality. Three species were isolated from coffee from the southwest of São...... Paulo state and selected for the study: Penicillium brevicompactum, Aspergillus luchuensis (belonging to section Nigri) and Penicillium sp. nov. (related to Penicillium crustosum). VCs produced by the fungal inoculated in raw coffee beans were extracted and tentatively identified by SPME...

Analysis of activity in swine producers group based on agricultural producers association in Biała district

Directory of Open Access Journals (Sweden)

Damian Knecht

2013-03-01

Full Text Available The process of pigs producer groups formation in Poland is quite dynamic. Currently on the pork market 181 groups operate, which includes about 4000 swine producers. The aim of this study was to characterize the activities of the Agricultural Producers Association in Biała District. The research tool was a personal questionnaire and the research sample consisted of 30 farmers. It has been shown that after joining the producers group, the investigated households reported an increase in sales volume and improved the flock production parameters. Majority of the respondents were not satisfied with the cooperation with meat processing companies.

Preliminary Evaluation of Glyceric Acid-producing Ability of Acidomonas methanolica NBRC104435 from Glycerol Containing Methanol.

Science.gov (United States)

Sato, Shun; Kitamoto, Dai; Habe, Hiroshi

2017-06-01

Some acetic acid bacteria produce large amounts of glyceric acid (GA) from glycerol in culture broth. However, methanol, which is a major contaminant of raw glycerol derived from the biodiesel fuel industry, sharply decreases cell growth and GA production [AMB Express, 3, 20, 2013]. Thus, we evaluated the methylotrophic acetic acid bacterium Acidomonas methanolica NBRC104435 for its ability to produce GA from glycerol containing methanol. This strain accumulated GA in its culture broth when 1-3 wt% glycerol was available as a carbon source. We observed improved cell growth and GA accumulation when 1 vol% methanol was added to the 3-5 wt% glycerol medium. The maximum concentration of GA was 12.8 g/L in medium containing 3 wt% glycerol plus 1 vol% methanol. In addition, the enantiomeric excess (ee) of the GA produced was revealed to be 44%, indicating that this strain converted glycerol to d-GA with a lower enantioselectivity than other acetic acid bacteria, which had 70-99% ee.

The Governance of Fair Trade System: Evidence from Small Honey Producers in Rio Grande do Sul

Directory of Open Access Journals (Sweden)

Luciana Marques Vieira

2009-10-01

Full Text Available This paper discusses Fair Trade [FT] certification as a way to include small producers in global value chains, and identifies the main barriers for small honey producers from RS to meet these criteria. A new trading system such as FT has been providing access for food products coming from small farmers from developing countries. The method of this study integrates global value chain analysis and the methodology proposed by Paul (2005 to analyse FT as development projects. This study is three-fold: first to characterise the FT system; then to present the role of governance by third party certifiers such as FLO-CERT and finally to provide empirical evidence of the main difficulties that small producers have to comply with FT, such as export and organisation capacity. Our findings show that large retailers recently became big players in the FT system. The certification costs are high but can provide market access though there is a risk of overspecialisation.

Organic substances in produced and formation water from unconventional natural gas extraction in coal and shale

Science.gov (United States)

Orem, William H.; Tatu, Calin A.; Varonka, Matthew S.; Lerch, Harry E.; Bates, Anne L.; Engle, Mark A.; Crosby, Lynn M.; McIntosh, Jennifer

2014-01-01

Organic substances in produced and formation water from coalbed methane (CBM) and gas shale plays from across the USA were examined in this study. Disposal of produced waters from gas extraction in coal and shale is an important environmental issue because of the large volumes of water involved and the variable quality of this water. Organic substances in produced water may be environmentally relevant as pollutants, but have been little studied. Results from five CBM plays and two gas shale plays (including the Marcellus Shale) show a myriad of organic chemicals present in the produced and formation water. Organic compound classes present in produced and formation water in CBM plays include: polycyclic aromatic hydrocarbons (PAHs), heterocyclic compounds, alkyl phenols, aromatic amines, alkyl aromatics (alkyl benzenes, alkyl biphenyls), long-chain fatty acids, and aliphatic hydrocarbons. Concentrations of individual compounds range from gas shale unimpacted by production chemicals have a similar range of compound classes as CBM produced water, and TOC levels of about 8 mg/L. However, produced water from the Marcellus Shale using hydraulic fracturing has TOC levels as high as 5500 mg/L and a range of added organic chemicals including, solvents, biocides, scale inhibitors, and other organic chemicals at levels of 1000 s of μg/L for individual compounds. Levels of these hydraulic fracturing chemicals and TOC decrease rapidly over the first 20 days of water recovery and some level of residual organic contaminants remain up to 250 days after hydraulic fracturing. Although the environmental impacts of the organics in produced water are not well defined, results suggest that care should be exercised in the disposal and release of produced waters containing these organic substances into the environment because of the potential toxicity of many of these substances.

Simulations of Large-Area Electron Beam Diodes

Science.gov (United States)

Swanekamp, S. B.; Friedman, M.; Ludeking, L.; Smithe, D.; Obenschain, S. P.

1999-11-01

Large area electron beam diodes are typically used to pump the amplifiers of KrF lasers. Simulations of large-area electron beam diodes using the particle-in-cell code MAGIC3D have shown the electron flow in the diode to be unstable. Since this instability can potentially produce a non-uniform current and energy distribution in the hibachi structure and lasing medium it can be detrimental to laser efficiency. These results are similar to simulations performed using the ISIS code.(M.E. Jones and V.A. Thomas, Proceedings of the 8^th) International Conference on High-Power Particle Beams, 665 (1990). We have identified the instability as the so called ``transit-time" instability(C.K. Birdsall and W.B. Bridges, Electrodynamics of Diode Regions), (Academic Press, New York, 1966).^,(T.M. Antonsen, W.H. Miner, E. Ott, and A.T. Drobot, Phys. Fluids 27), 1257 (1984). and have investigated the role of the applied magnetic field and diode geometry. Experiments are underway to characterize the instability on the Nike KrF laser system and will be compared to simulation. Also some possible ways to mitigate the instability will be presented.

Producing deep-water hydrocarbons

International Nuclear Information System (INIS)

Pilenko, Thierry

2011-01-01

Several studies relate the history and progress made in offshore production from oil and gas fields in relation to reserves and the techniques for producing oil offshore. The intention herein is not to review these studies but rather to argue that the activities of prospecting and producing deep-water oil and gas call for a combination of technology and project management and, above all, of devotion and innovation. Without this sense of commitment motivating men and women in this industry, the human adventure of deep-water production would never have taken place

Novel concept for producing energy integrating a solar collector with a man made mountain hollow

International Nuclear Information System (INIS)

Zhou Xinping; Yang Jiakuan; Wang Jinbo; Xiao Bo

2009-01-01

The concept of the solar chimney thermal power technology was proven with the successful operation of the Manzanares prototype built in the 1980s. However, all previous attempts at producing energy from a commercial solar chimney thermal power plant on a large scale have failed because of bad engineering and safety. A novel concept for producing energy by integrating a solar collector with a mountain hollow is presented and described. Solar energy is collected in the collector and heats the ground, which is used to store heat energy and heat the indoor air. Then, the hot air is forced by the pressure difference between it and the ambient air to move along the tilted segment and up the vertical segment of the 'chimney', driving the turbine generators to generate electricity. The mountain hollow, formed by excavation in a large-elevation mountain, can avoid the safety issues of erecting a gigantic concrete chimney, which is needed for commercial solar chimney thermal power plants. Furthermore, it can also save a great amount of construction materials for constructing a robust chimney structure and reduce the energy cost to a level less than that of a clean coal power plant, providing a good solution to the reclamation and utilization of undeveloped mountains, especially in mountainous countries

Novel concept for producing energy integrating a solar collector with a man made mountain hollow

Energy Technology Data Exchange (ETDEWEB)

Zhou Xinping [School of Civil Engineering and Mechanics, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan, Hubei 430074 (China)], E-mail: zhxpmark@hotmail.com; Yang Jiakuan; Wang Jinbo; Xiao Bo [School of Environmental Science and Engineering, Huazhong University of Science and Technology, 1037 Luoyu Road Wuhan, Hubei 430074 (China)

2009-03-15

The concept of the solar chimney thermal power technology was proven with the successful operation of the Manzanares prototype built in the 1980s. However, all previous attempts at producing energy from a commercial solar chimney thermal power plant on a large scale have failed because of bad engineering and safety. A novel concept for producing energy by integrating a solar collector with a mountain hollow is presented and described. Solar energy is collected in the collector and heats the ground, which is used to store heat energy and heat the indoor air. Then, the hot air is forced by the pressure difference between it and the ambient air to move along the tilted segment and up the vertical segment of the 'chimney', driving the turbine generators to generate electricity. The mountain hollow, formed by excavation in a large-elevation mountain, can avoid the safety issues of erecting a gigantic concrete chimney, which is needed for commercial solar chimney thermal power plants. Furthermore, it can also save a great amount of construction materials for constructing a robust chimney structure and reduce the energy cost to a level less than that of a clean coal power plant, providing a good solution to the reclamation and utilization of undeveloped mountains, especially in mountainous countries.

Novel concept for producing energy integrating a solar collector with a man made mountain hollow

Energy Technology Data Exchange (ETDEWEB)

Zhou, Xinping [School of Civil Engineering and Mechanics, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan, Hubei 430074 (China); Yang, Jiakuan; Wang, Jinbo; Xiao, Bo [School of Environmental Science and Engineering, Huazhong University of Science and Technology, 1037 Luoyu Road Wuhan, Hubei 430074 (China)

2009-03-15

The concept of the solar chimney thermal power technology was proven with the successful operation of the Manzanares prototype built in the 1980s. However, all previous attempts at producing energy from a commercial solar chimney thermal power plant on a large scale have failed because of bad engineering and safety. A novel concept for producing energy by integrating a solar collector with a mountain hollow is presented and described. Solar energy is collected in the collector and heats the ground, which is used to store heat energy and heat the indoor air. Then, the hot air is forced by the pressure difference between it and the ambient air to move along the tilted segment and up the vertical segment of the 'chimney', driving the turbine generators to generate electricity. The mountain hollow, formed by excavation in a large-elevation mountain, can avoid the safety issues of erecting a gigantic concrete chimney, which is needed for commercial solar chimney thermal power plants. Furthermore, it can also save a great amount of construction materials for constructing a robust chimney structure and reduce the energy cost to a level less than that of a clean coal power plant, providing a good solution to the reclamation and utilization of undeveloped mountains, especially in mountainous countries. (author)

Tekna's produced water conference 2005

International Nuclear Information System (INIS)

2005-01-01

The conference has 22 presentations discussing topics on discharge reduction, produced water quality, produced water re-injection, chemicals particularly environmentally friendly ones, separation technology, reservoir souring, total water management systems, pollution, oil in water problems and platform operation. Various field tests and experiences particularly from the offshore petroleum sector are presented (tk)

Faecal carriage of extended-spectrum b-lactamase-producing and AMpC b-lactamase-producing bacteria among Danish army recruits

DEFF Research Database (Denmark)

Hammerum, A.M; Lester, C.H; Jakobsen, L

2011-01-01

During May and June 2008, 84 Danish army recruits were tested for faecal carriage of extended-spectrum b-lactamase (ESBL)- producing and AmpC b-lactamase-producing bacteria. Three ESBL-producing (CTX-M-14a) Escherichia coli isolates, two AmpC-producing (CMY-2) E. coli isolates and one Amp...

Diversity of the Mountain Flora of Central Asia with Emphasis on Alkaloid-Producing Plants

Directory of Open Access Journals (Sweden)

Karimjan Tayjanov

2017-02-01

Full Text Available The mountains of Central Asia with 70 large and small mountain ranges represent species-rich plant biodiversity hotspots. Major mountains include Saur, Tarbagatai, Dzungarian Alatau, Tien Shan, Pamir-Alai and Kopet Dag. Because a range of altitudinal belts exists, the region is characterized by high biological diversity at ecosystem, species and population levels. In addition, the contact between Asian and Mediterranean flora in Central Asia has created unique plant communities. More than 8100 plant species have been recorded for the territory of Central Asia; about 5000–6000 of them grow in the mountains. The aim of this review is to summarize all the available data from 1930 to date on alkaloid-containing plants of the Central Asian mountains. In Saur 301 of a total of 661 species, in Tarbagatai 487 out of 1195, in Dzungarian Alatau 699 out of 1080, in Tien Shan 1177 out of 3251, in Pamir-Alai 1165 out of 3422 and in Kopet Dag 438 out of 1942 species produce alkaloids. The review also tabulates the individual alkaloids which were detected in the plants from the Central Asian mountains. Quite a large number of the mountain plants produce neurotoxic and cytotoxic alkaloids, indicating that a strong chemical defense is needed under the adverse environmental conditions of these mountains with presumably high pressure from herbivores.

Preparation of cyclotron-produced {sup 186}Re and comparison with reactor-produced {sup 186}Re and generator-produced {sup 188}Re for the labeling of bombesin

Energy Technology Data Exchange (ETDEWEB)

Moustapha, Moustapha E. [Department of Chemistry, University of Missouri-Columbia, Columbia, MO 65211 (United States); University of Missouri Research Reactor (MURR), University of Missouri-Columbia, Columbia, MO 65211 (United States); Ehrhardt, Gary J. [Department of Chemistry, University of Missouri-Columbia, Columbia, MO 65211 (United States); University of Missouri Research Reactor (MURR), University of Missouri-Columbia, Columbia, MO 65211 (United States); Smith, Charles J. [Department of Radiology, University of Missouri-Columbia, Columbia, MO 65211 (United States); University of Missouri Research Reactor (MURR), University of Missouri-Columbia, Columbia, MO 65211 (United States); Research Services, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201 (United States); Szajek, Lawrence P. [Positron Emission Tomography Department, National Institutes of Health, Bethesda, MD 20892-1180 (United States); Eckelman, William C. [Positron Emission Tomography Department, National Institutes of Health, Bethesda, MD 20892-1180 (United States); Jurisson, Silvia S. [Department of Chemistry, University of Missouri-Columbia, Columbia, MO 65211 (United States)]. E-mail: jurissons@missouri.edu

2006-01-15

The radioisotopes {sup 186}Re and {sup 188}Re have been extensively investigated for various forms of radiotherapy due to their useful and high-abundance {beta} particle emissions, low-abundance and imageable {gamma}-rays, and chemical resemblance to technetium. In addition, {sup 188}Re is available in no-carrier-added (NCA) form from long lived W-188 generators, whereas {sup 186}Re can be produced in large quantities from reactors, although not in NCA form. However, NCA {sup 186}Re can be produced on a cyclotron by a (p,n) reaction on {sup 186}W. The purpose of this study was to compare labeling of the peptide bombesin with these three forms of rhenium radioisotopes. Cyclotron-produced NCA {sup 186}Re was separated radiochemically from enriched {sup 186}W (96.9%) targets using high-purity methyl ethyl ketone (MEK). The resulting {sup 186}Re-MEK was then loaded onto a small alumina column to separate the resulting NCA {sup 186}Re from any remaining {sup 186}W. The experimental levels of impurities associated with {sup 186}Re at the end of the separation process were found to be 5.7x10{sup -6} Ci of {sup 182}Re (0.57%, t {sub 1/2}=12.7 h) and 1.283x10{sup -5} Ci of {sup 182m}Re (1.28%, t {sub 1/2}=2.67 days). The radionuclidic purity of the separated {sup 186}Re was found to be 99.6%, whereas the chemical identity was determined by reversed phase high-performance liquid chromatography (RP-HPLC) to be perrhenate ({sup 186}ReO{sub 4} {sup -}). Generator-produced {sup 188}ReO{sub 4} {sup -} from a {sup 188}W/{sup 188}Re generator (Oak Ridge National Laboratory) and CA {sup 186}ReO{sub 4} {sup -} produced from a {sup 185}Re(n,{gamma}){sup 186}Re reaction at the University of Missouri Research Reactor (MURR) were used for comparison with the NCA {sup 186}Re in subsequent studies. N{sub 3}S-5-Ava-BBN(7-14)NH{sub 2} conjugates provide flexibility for designing {sup 186,188}Re-labeled conjugates that retain high in vitro and in vivo specificity targeting of GRP receptor

Combined process automation for large-scale EEG analysis.

Science.gov (United States)

Sfondouris, John L; Quebedeaux, Tabitha M; Holdgraf, Chris; Musto, Alberto E

2012-01-01

Epileptogenesis is a dynamic process producing increased seizure susceptibility. Electroencephalography (EEG) data provides information critical in understanding the evolution of epileptiform changes throughout epileptic foci. We designed an algorithm to facilitate efficient large-scale EEG analysis via linked automation of multiple data processing steps. Using EEG recordings obtained from electrical stimulation studies, the following steps of EEG analysis were automated: (1) alignment and isolation of pre- and post-stimulation intervals, (2) generation of user-defined band frequency waveforms, (3) spike-sorting, (4) quantification of spike and burst data and (5) power spectral density analysis. This algorithm allows for quicker, more efficient EEG analysis. Copyright © 2011 Elsevier Ltd. All rights reserved.

Composites of Heavy Rain Producing Elevated Thunderstorms in the Central United States

Directory of Open Access Journals (Sweden)

Laurel P. McCoy

2017-01-01

Full Text Available Composite analyses of the atmosphere over the central United States during elevated thunderstorms producing heavy rainfall are presented. Composites were created for five National Weather Service County Warning Areas (CWAs in the region. Events studied occurred during the warm season (April–September during 1979–2012. These CWAs encompass the region determined previously to experience the greatest frequency of elevated thunderstorms in the United States. Composited events produced rainfall of >50 mm 24 hr−1 within the selected CWA. Composites were generated for the 0–3 hr period prior to the heaviest rainfall, 6–9 hours prior to it, and 12–15 hours prior to it. This paper focuses on the Pleasant Hill, Missouri (EAX composites, as all CWA results were similar; also these analyses focus on the period 0–3 hours prior to event occurrence. These findings corroborate the findings of previous authors. What is offered here that is unique is (1 a measure of the interquartile range within the composite mean fields, allowing for discrimination between variable fields that provided a strong reliable signal, from those that may appear strong but possess large variability, and (2 composite soundings of two subclasses of elevated thunderstorms. Also, a null case (one that fits the composite but failed to produce significant rainfall is also examined for comparison.

Radicinols and radicinin phytotoxins produced by Alternaria radicina on carrots.

Science.gov (United States)

Solfrizzo, Michele; Vitti, Carolina; De Girolamo, Annalisa; Visconti, Angelo; Logrieco, Antonio; Fanizzi, Francesco P

2004-06-02

The phytotoxin epi-radicinol, a diastereomer of radicinol, was isolated from large cultures of Alternaria radicina grown on carrot slices and identified by GC-MS, LC-MS, (1)H NMR, and (13)C NMR. Four strains of A. radicina isolated from rotted carrot produced epi-radicinol as the major metabolite (up to 39414 microg/g) together with radicinol (up to 2423 microg/g), and, to a lesser extent, radicinin when cultured on carrot slices, whereas on rice they mainly produced radicinin (2486-53800 microg/g). Radicinin and epi-radicinol reduced root elongation of germinating carrot seeds at concentrations of 10-20 microg/mL. Carrot samples naturally infected by A. radicina contained detectable quantities of epi-radicinol also in combination with lower levels of radicinin or radicinol. Accumulation of radicinols and radicinin in stored carrots, either naturally contaminated or artificially inoculated with A. radicina, was stimulated by successive temperature rises from 1 to 10 degrees C and from 10 to 20 degrees C, reaching maximum levels of 60 microg/g epi-radicinol and 26 microg/g radicinin. This is the first report on the production of radicinols by A. radicina and its natural occurrence in carrots in association with radicinin.

Interaction among competitive producers in the electricity market: An iterative market model for the strategic management of thermal power plants

International Nuclear Information System (INIS)

Carraretto, Cristian; Zigante, Andrea

2006-01-01

The liberalization of the electricity sector requires utilities to develop sound operation strategies for their power plants. In this paper, attention is focused on the problem of optimizing the management of the thermal power plants belonging to a strategic producer that competes with other strategic companies and a set of smaller non-strategic ones in the day-ahead market. The market model suggested here determines an equilibrium condition over the selected period of analysis, in which no producer can increase profits by changing its supply offers given all rivals' bids. Power plants technical and operating constraints are considered. An iterative procedure, based on the dynamic programming, is used to find the optimum production plans of each producer. Some combinations of power plants and number of producers are analyzed, to simulate for instance the decommissioning of old expensive power plants, the installation of new more efficient capacity, the severance of large dominant producers into smaller utilities, the access of new producers to the market. Their effect on power plants management, market equilibrium, electricity quantities traded and prices is discussed. (author)

Hydrothermal processes above the Yellowstone magma chamber: Large hydrothermal systems and large hydrothermal explosions

Science.gov (United States)

Morgan, L.A.; Shanks, W.C. Pat; Pierce, K.L.

2009-01-01

and vein-fi lling; and (5) areal dimensions of many large hydrothermal explosion craters in Yellowstone are similar to those of its active geyser basins and thermal areas. For Yellowstone, our knowledge of hydrothermal craters and ejecta is generally limited to after the Yellowstone Plateau emerged from beneath a late Pleistocene icecap that was roughly a kilometer thick. Large hydrothermal explosions may have occurred earlier as indicated by multiple episodes of cementation and brecciation commonly observed in hydrothermal ejecta clasts. Critical components for large, explosive hydrothermal systems include a watersaturated system at or near boiling temperatures and an interconnected system of well-developed joints and fractures along which hydrothermal fluids flow. Active deformation of the Yellowstone caldera, active faulting and moderate local seismicity, high heat flow, rapid changes in climate, and regional stresses are factors that have strong infl uences on the type of hydrothermal system developed. Ascending hydrothermal fluids flow along fractures that have developed in response to active caldera deformation and along edges of low-permeability rhyolitic lava flows. Alteration of the area affected, self-sealing leading to development of a caprock for the hydrothermal system, and dissolution of silica-rich rocks are additional factors that may constrain the distribution and development of hydrothermal fields. A partial lowpermeability layer that acts as a cap to the hydrothermal system may produce some over-pressurization, thought to be small in most systems. Any abrupt drop in pressure initiates steam fl ashing and is rapidly transmitted through interconnected fractures that result in a series of multiple large-scale explosions contributing to the excavation of a larger explosion crater. Similarities between the size and dimensions of large hydrothermal explosion craters and thermal fields in Yellowstone may indicate that catastrophic events which result in l

Molecular analysis of Piscine Reovirus (PRV) vaccine antigens produced in tobacco and lettuce

OpenAIRE

Dahl, Even Klyve

2016-01-01

Aquaculture is emerging to be one of the most important food industries in the world, and will be a crucial part of securing food supply for a population expected to reach close to 10 billion by 2050. Norway produced 1.3 million tons of Atlantic salmon in 2015, with a sales value of 44.3 billion NOK. This is done in marine cage systems which are dependent on keeping a large number of individuals at high density. This intense nature of fish farming increases the risk of infectious diseases. ...

The environmental agreement may lead to large losses for the oil producers. The Kyoto mechanisms are very important to Norway

International Nuclear Information System (INIS)

1999-01-01

The article presents an economic model study of the implications of an climatic agreement. Two main scenarios are presented: 1) The Kyoto protocol is extended to 2020. 2) All counties ratify a climatic agreement. The conclusions are that the Kyoto protocol may have great effects on the oil and gas markets and large economic consequences for Norway. It is therefore mandatory to extensively use the Kyoto mechanisms such as trade with quotas, common implementation and the green development mechanism

Can Producing Oil Store Carbon? Greenhouse Gas Footprint of CO2EOR, Offshore North Sea.

Science.gov (United States)

Stewart, R Jamie; Haszeldine, R Stuart