WorldWideScience

Sample records for accidentally exposed individuals

  1. Learning From Biomarkers in Victims Accidentally Exposed to Ionizing Radiation

    Institute of Scientific and Technical Information of China (English)

    Yan Wang; Liqing Du; Chang Xu; Qin Wang; Zhiyi Song; Jianxiang Liu; Xu Su

    2016-01-01

    Biomarkers,such as chromosome aberration and micronuclei assays,prove to be reliable for facilitating clinical diagnosis in radiation accidents.In a radiation accident in India,chromosomal aberration,γ-H2AX,as well as other blood markers,were detected in accidentally exposed victims.This multi-parametric approach aided in confirming that individuals had been exposed by ionizing radiation.However,doses were impossible to estimate because of a 30-day delay in accident awareness.Exposure dose for victims was estimated using a dose-response curve previously established.Dose estimation,blood cell depletion kinetics,and no appearance of prodromal symptoms suggested that doses of exposure were low.Hematologic investigation,sampling time,and chromosome aberration scoring were all proposed according to data from the victims exposed to 60Co.Finally,knowledge regarding chromosome aberration analysis and the importance of international co-operation and assistance should be shared from this accident.

  2. Lead excretion in milk of accidentally exposed dairy cattle.

    Science.gov (United States)

    Bischoff, Karyn; Higgins, William; Thompson, Belinda; Ebel, Joseph G

    2014-01-01

    Lead (Pb) exposure in dairy cattle is associated with economic losses due to mortality and treatment costs, but with production animals there is also risk to the human food chain. The first objective of this study was to quantify the Pb concentration in milk from Pb-exposed cattle. The second objective was to correlate blood and milk Pb concentrations from individual cows. The third objective was long-term monitoring to determine the duration of milk contamination after exposure ceased. A dairy herd of more than 100 cows was accidentally exposed to Pb-contaminated feed. Milk and blood were collected for Pb analysis. Serial collection of milk samples continued for 2.5 years. The initial concentration of Pb in bulk tank milk was 0.0999 mg l⁻¹. The highest milk Pb concentration from an individual cow was 0.4657 mg l⁻¹ and the highest blood Pb concentration was 1.216 mg l⁻¹. One milk sample collected at the end of the study (day 922) contained 0.0117 mg Pb l⁻¹ of Pb. The calculated relationship between milk (y) and blood (x) Pb concentration was ln(y) = 3.4(x) - 2.21 (R² = 0.98).

  3. 用FISH技术对忻州事故宫内受照者进行回顾性剂量重建%Retrospective dose estimation for individuals exposed to accidental exposure in uterus with fluorescence in situ hybridization

    Institute of Scientific and Technical Information of China (English)

    陆雪; 刘青杰; 赵骅; 梁莉; 张淑兰; 封江彬; 张照辉; 陈德清; 马力文; 贾廷珍

    2010-01-01

    目的 对忻州事故中宫内受照者"京"进行回顾性剂量重建.方法 受照后16年取"京"及其母亲"芳"的外周静脉血,用常规方法分析非稳定性染色体畸变,用CB法分析双核淋巴细胞微核;用全染色体探针的FISH方法分析染色体易位,参照本实验室建立的全基因组易位率与吸收剂量之间的剂量-效应曲线进行剂量估算.参照"芳"的剂量校正系数推算"京"在宫内的受照剂量.结果 受照16年后未观察到两位受照者的外周血非稳定性染色体畸变,淋巴细胞微核率在正常范围内.参照本实验室建立的吸收剂量与全基因组易位率之间的剂量-效应曲线,"芳"在16年后用FISH方法估算的剂量为0.76(0.41~1.00)Gy,而"芳"在事故后短期内估算的生物剂量为2.30(2.07~2.50)Gy,其剂量校正系数为3.03;"京"在16年后估算的剂量为0.61(0.44~0.86)Gy,推算"京"在宫内受照的剂量为1.85(1.33~2.61)Gy.结论 16年后用FISH方法对宫内受照者进行剂量重建,参照受照母亲的剂量校正系数,可推算出胎儿宫内受照的大致剂量,为临床提供依据.%Objective To reconstruct the absorbed dose for the individual who was accidentally exposed in uterus 16 years ago.Methods Peripheral blood samples were taken from the victim and her mother.The dicentric and centric ring chromosome aberrations were analyzed with conventional method,the micronucleus was observed with cytokinesis-block micronucleus method,and fluorescence in situ hybridization (FISH) with chromosomes 1,2 and 4 painting probes were used for translocation detection.Dose was estimated according to the standard dose-response curves previously established.Results No unstable chromosome aberrations and normal micronucleus frequencies were observed in two persons 16years after the accident.Against the established dose-response curves with FISH,the doses to the mother and her daughter were 0.76 Gy (95% GI 0.41-1.00 Gy) and 0.61 Gy (95% CI 0

  4. Medical status of Marshallese accidentally exposed to 1954 Bravo fallout radiation: January 1980-December 1982

    Energy Technology Data Exchange (ETDEWEB)

    Adams, W.H.; Harper, J.A.; Rittmaster, R.S.; Heotis, P.M.; Scott, W.A.

    1984-01-01

    This report updates, for 1980 through 1982, the results of continuing medical surveillance of a Marshallese population accidentally exposed to radioactive fallout in March 1954. The originally exposed Marshallese population comprised 64 persons on Rongelap Atoll who each received, on the average, an estimated 190 rads of absorbed external gamma radiation, 18 on Ailingnae Atoll who received 110 rads, and 159 on Utirik who received 11 rads. There were, in addition, 3 persons in utero on Rongelap, 1 person in utero on Ailingnae, and 8 persons in utero on Utirik who are considered exposed. The recipients of primary medical care include exposed and comparison populations as well as a rather large number of additional beneficiaries who are seen on a humanitarian basis of practical need and resource availability. In recent years, about 1400 people have been seen annually. This report, however, deals with four clearly defined groups: the remaining individuals who were exposed to radioactive fallout on Rongelap, Ailingnae, and Utirik in 1954 (including those in utero), and a comparison population of individuals from Rongelap who were unexposed. The number of persons now in each exposure category are 51, 12, 116, and 137, respectively. 100 references, 4 figures, 5 tables. (ACR)

  5. Genomic damage in children accidentally exposed to ionizing radiation

    DEFF Research Database (Denmark)

    Fucic, A; Brunborg, G; Lasan, R

    2007-01-01

    During the last decade, our knowledge of the mechanisms by which children respond to exposures to physical and chemical agents present in the environment, has significantly increased. Results of recent projects and programmes focused on children's health underline a specific vulnerability...... of children to environmental genotoxicants. Environmental research on children predominantly investigates the health effects of air pollution while effects from radiation exposure deserve more attention. The main sources of knowledge on genome damage of children exposed to radiation are studies performed...... after the Chernobyl nuclear plant accident in 1986. The present review presents and discusses data collected from papers analyzing genome damage in children environmentally exposed to ionizing radiation. Overall, the evidence from the studies conducted following the Chernobyl accident, nuclear tests...

  6. Medical status of Marshallese accidentally exposed to 1954 Bravo fallout radiation, January 1983-December 1984

    Energy Technology Data Exchange (ETDEWEB)

    Adams, W.H.; Engle, J.R.; Harper, J.A.; Heotis, P.M.; Scott, W.A.

    1986-01-01

    March 1, 1984, was the 30th anniversary of the Bravo thermonuclear test that resulted in the accidental exposure of the populations of Rongelap and Utirik atolls to radioactive fallout. The chronicling of the medical events resulting from that exposure is continued in this report, which covers the period from January 1983 through December 1984. An updated listing of all relevant publications from the Medical Department Brookhaven National Laboratory, is presented in the Reference Section. Thirty years of observation continue to show no detectable increase in mortality in the exposed population as a result of that exposure. The survival curves of the high-exposure Rongelap group, the low-exposure Utirik population, and an unexposed group of Rongelap people matched by age and sex to the exposed Rongelap group in 1957 continue to be similar. 89 refs., 2 figs., 6 tabs.

  7. Individual dose due to radioactivity accidental release from fusion reactor.

    Science.gov (United States)

    Nie, Baojie; Ni, Muyi; Wei, Shiping

    2017-04-05

    As an important index shaping the design of fusion safety system, evaluation of public radiation consequences have risen as a hot topic on the way to develop fusion energy. In this work, the comprehensive public early dose was evaluated due to unit gram tritium (HT/HTO), activated dust, activated corrosion products (ACPs) and activated gases accidental release from ITER like fusion reactor. Meanwhile, considering that we cannot completely eliminate the occurrence likelihood of multi-failure of vacuum vessel and tokamak building, we conservatively evaluated the public radiation consequences and environment restoration after the worst hypothetical accident preliminarily. The comparison results show early dose of different unit radioactivity release under different conditions. After further performing the radiation consequences, we find it possible that the hypothetical accident for ITER like fusion reactor would result in a level 6 accident according to INES, not appear level 7 like Chernobyl or Fukushima accidents. And from the point of environment restoration, we need at least 69 years for case 1 (1kg HTO and 1000kg dust release) and 34-52years for case 2 (1kg HTO and 10kg-100kg dust release) to wait the contaminated zone drop below the general public safety limit (1mSv per year) before it is suitable for human habitation.

  8. Medical status of Marshallese accidentally exposed to 1954 Bravo fallout radiation: January 1988 through December 1991

    Energy Technology Data Exchange (ETDEWEB)

    Howard, J.E.; Heotis, P.M.; Scott, W.A.; Adams, W.H.

    1995-07-01

    The purpose of this report is to disseminate information concerning the medical status of 253 Marshallese exposed to fallout radiation in 1954. This report discusses the medical care provided and the medical findings for the years 1988-1991. Details of the BRAVO thermonuclear accident that caused the exposure have been published, and a 1955 article in the Journal of the American Medical Association describing the acute medical effects in the exposed population remains a definitive and relevant description of events. Participation in the Marshall Islands Medical Program by the exposed Marshallese is voluntary. In the spring and fall of each year, medical surveillance is provided to exposed and unexposed cohorts. Examinations performed include: a cancer-related examination as defined by the American Society, an annual thyroid examination and thyroid function testing, serum prolactin testing looking for pituitary tumors, annual blood counts to include platelets, and evaluation for paraneoplastic evidence of neoplasms. This report details the medical program, medical findings, and thyroid surgery findings. Deaths (4 exposed and 10 nonexposed) that occurred during the reporting period are discussed. There is a mild but relatively consistent depression of neutrophil, lymphocyte, and platelet concentrations in the blood of the exposed population. This depression appears to be of no clinical significance. Thyroid hypofunction, either clinical or biochemical, has been documented as a consequence of radiation exposure in 14 exposed individuals. Previously, one other exposed person was diagnosed with basal cell carcinoma. During this reporting period, a thyroid nodule was identified in an individual who was in utero during the exposure. Upon pathologic review, the nodule was diagnosed as occult papillary carcinoma.

  9. [Factors associated with the danger of accidental falls among institutionalized elderly individuals: an integrative review].

    Science.gov (United States)

    Gomes, Erika Carla Cavalcanti; Marques, Ana Paula de Oliveira; Leal, Márcia Carréra Campos; Barros, Benvinda Pereira de

    2014-08-01

    The scope of this research is to identify the major risk factors associated with accidental falls among the elderly. It involves an integrative review of the literature between 2002 and 2012 in English and Portuguese. The selection of articles was based on the following key words in the Lilacs, Medline and BDENF databases: accidental falls, homes for the elderly and health services. In the final sample 19 articles were selected, of which 11 were national and 8 were international. They indicate that the major factors related to the risk of accidental falls in Homes for the Elderly are: being female, being diagnosed with chronic disease, treatment with benzodiazepine, earlier cases of accident falls, and mobility restriction. The research reveals that architectonic and furniture inadequacies in Homes for the Elderly may be predisposing factors for accidental falls. Analysis of the articles reveals the need for further longitudinal studies and, consequently, enhanced monitoring of the conditions of the functional capacity of the elderly, especially the risks related to falls, considered one of the leading causes of death among institutionalized elderly individuals.

  10. Protection of man: the exposed individual

    Energy Technology Data Exchange (ETDEWEB)

    Bohnstedt, A.; Knebel, J.U. [Programme Nuclear Safety Research, Karlsruhe Institute of Technology, Herrmann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Breustedt, B. [Institute for Radiation Research, Karlsruhe Institute of Technology, Herrmann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany)

    2010-07-01

    Present methods for quantifying radiation exposure rely on a standardized reference man (75 kg) with defined average anatomical and physiological data. But individual person actually exposed differs from this idealized standard man. Therefore the focus of investigations at the Institute for Radiation Research (Institut fuer Strahlenforschung, ISF) which was founded at Karlsruhe Institute of Technology (Karlsruher Institut fuer Technologie, KIT) in 2009 is based on the vision to place the exposed individual with its anatomical and physiological particularities, under consideration of age, gender, body height, body shape and environment, in the centre of an individual-related quantification of the external and internal radiation exposure. Research work at the ISF is aiming at quantifying radiation exposure by improved determination of doses essentially caused by external radiation fields and the intake of radionuclides into the body. The three main topics of the institute are - external dosimetry (e.g. using a (voxel) model of the hand to simulate skin dose distribution); - internal dosimetry (e.g. body size related efficiency calibration of in-vivo counting equipment); - numerical methods/modeling (e.g. development of a mathematical/voxel-hybrid model of the human body). (authors)

  11. Fallout: The experiences of a medical team in the care of a Marshallese population accidentally exposed to fallout radiation

    Energy Technology Data Exchange (ETDEWEB)

    Conard, R.A.

    1991-01-01

    This report presents an historical account of the experiences of the Brookhaven Medical team in the examination and treatment of the Marshallese people following their accidental exposure to radioactive fallout in 1954. This is the first time that a population has been heavily exposed to radioactive fallout, and even though this was a tragic mishap, the medical findings have provided valuable information for other accidents involving fallout such as the recent reactor accident at Chernobyl. Particularly important has been the unexpected importance of radioactive iodine in the fallout in producing thyroid abnormalities.

  12. Fallout: The experiences of a medical team in the care of a Marshallese population accidentally exposed to fallout radiation

    Energy Technology Data Exchange (ETDEWEB)

    Conard, R.A.

    1991-12-31

    This report presents an historical account of the experiences of the Brookhaven Medical team in the examination and treatment of the Marshallese people following their accidental exposure to radioactive fallout in 1954. This is the first time that a population has been heavily exposed to radioactive fallout, and even though this was a tragic mishap, the medical findings have provided valuable information for other accidents involving fallout such as the recent reactor accident at Chernobyl. Particularly important has been the unexpected importance of radioactive iodine in the fallout in producing thyroid abnormalities.

  13. Blood biomarkers in metal scrap workers accidentally exposed to ionizing radiation: a case study.

    Science.gov (United States)

    Gupta, M L; Srivastava, N N; Dutta, S; Shukla, S K; Dutta, A; Verma, S; Devi, M

    2013-12-01

    The detrimental effect of nuclear accidents due to localized or whole body radiation exposure results in severe cellular damage. The current study was carried out to evaluate radiation-mediated variability in blood components of metal scrap workers exposed accidently to cobalt-60 source. Blood samples collected initially from five hospitalized patients, coded P1-P5, were processed for total leukocyte counts (TLC), platelet (PLT) counts, haemoglobin, estimation of DNA double strand breaks by measuring phosphorylated form of H2AX (γ-H2AX) and chromosomal aberrations (dicentrics). Blood cells count (TLC), in all the patients except P2, was found decreased. Dicentrics increased in all the five patients. γ-H2AX was found significantly elevated in patients P2 and P4. After 3 days, 21 subjects working in close vicinity of accident site were evaluated for the above-mentioned markers to confirm their possibility of radiation exposure; however, all the parameters in these subjects were found within normal limits. Blood from patients P1-P5 was collected again after 11 days. Studies revealed exorbitant increase in γ-H2AX in lymphocytes and monocytes of patients P1, P4 and P5. TLC and PLT count in these patients had fallen further. Dicentrics declined with time in all the five patients. Based on the studied blood biomarkers, we conclude that the five subjects showed signs of radiation exposure. Measurement on radiation dose could not be performed in the current study; however, the generated data particularly on dicentrics provide ample evidence of radiation exposure.

  14. Personality and psychopathological profiles in individuals exposed to mobbing.

    Science.gov (United States)

    Girardi, Paolo; Monaco, Edoardo; Prestigiacomo, Claudio; Talamo, Alessandra; Ruberto, Amedeo; Tatarelli, Roberto

    2007-01-01

    Increasingly, mental health and medical professionals have been asked to assess claims of psychological harm arising from harassment at the workplace, or "mobbing." This study assessed the personality and psychopathological profiles of 146 individuals exposed to mobbing using validity, clinical, and content scales of the Minnesota Multiphasic Personality Inventory 2. Profiles and factor analyses were obtained. Two major dimensions emerged among those exposed to mobbing: (a) depressed mood, difficulty in making decisions, change-related anguish, and passive-aggressive traits (b) somatic symptoms, and need for attention and affection. This cross-sectional pilot study provides evidence that personality profiles of mobbing victims and psychological damage resulting from mobbing may be evaluated using standardized assessments, though a longitudinal study is needed to delineate cause-and-effect relationships.

  15. 10 CFR 63.312 - Required characteristics of the reasonably maximally exposed individual.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Required characteristics of the reasonably maximally exposed individual. 63.312 Section 63.312 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF... characteristics of the reasonably maximally exposed individual. The reasonably maximally exposed individual is...

  16. 40 CFR 197.21 - Who is the reasonably maximally exposed individual?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Who is the reasonably maximally exposed individual? 197.21 Section 197.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Standard § 197.21 Who is the reasonably maximally exposed individual? The reasonably maximally...

  17. Accidental hypothermia

    Directory of Open Access Journals (Sweden)

    Ivo Casagranda

    2006-02-01

    Full Text Available Hypothermia is defined as an unintentional decrease of core body temperature below 35 °C. In this article we discuss pathophysiology, clinical aspects and treatment of hypothermic patients. The most important treatment of hypothermia is the identification of the most appropriate method of rewarming. We report a case of cardiac arrest secondary to severe accidental hypothermia, that occured in a young man, do to prolonged exposure to low temperature in river water, successfully treated with extracorporeal blood warming.

  18. Accidental Innovation

    DEFF Research Database (Denmark)

    Austin, Robert D.; Devin, Lee; Sullivan, Erin E.

    2012-01-01

    Historical accounts of human achievement suggest that accidents can play an important role in innovation. In this paper, we seek to contribute to an understanding of how digital systems might support valuable unpredictability in innovation processes by examining how innovators who obtain value from...... they incorporate accidents into their deliberate processes and arranged surroundings. By comparing makers working in varied conditions, we identify specific factors (e.g., technologies, characteristics of technologies) that appear to support accidental innovation. We show that makers in certain specified...... conditions not only remain open to accident but also intentionally design their processes and surroundings to invite and exploit valuable accidents. Based on these findings, we offer advice for the design of digital systems to support innovation processes that can access valuable unpredictability....

  19. Serum Metabolomic Profiling of Sulphur Mustard-Exposed Individuals Using (1)H Nuclear Magnetic Resonance Spectroscopy.

    Science.gov (United States)

    Zamani, Zahra; Ghanei, Mostafa; Panahi, Yunus; Arjmand, Mohammad; Sadeghi, Sedigheh; Mirkhani, Fatemeh; Parvin, Shahram; Salehi, Maryam; Sahebkar, Amirhossein; Vahabi, Farideh

    2016-01-01

    Sulphur mustard is an alkylating agent that reacts with different cellular components, causing acute and delayed complications that may remain for decades after exposure. This study aimed to identify differentially expressed metabolites between mustard-exposed individuals suffering from chronic complications compared with unexposed individuals as the control group. Serum samples were obtained from 15 mustard-exposed individuals and 15 apparently healthy unexposed individuals. Metabolomic profiling was performed using (1)H nuclear magnetic resonance spectroscopy, and analyses were carried out using Chenomex and MATLAB softwares. Metabolites were identified using Human Metabolome Database, and the main metabolic pathways were identified using MetaboAnalyst software. Chemometric analysis of serum samples identified 11 differentially expressed metabolites between mustard-exposed and unexposed groups. The main pathways that were influenced by sulphur mustard exposure were related to vitamin B6 (down-regulation), bile acid (up-regulation) and tryptophan (down-regulation) metabolism. Metabolism of vitamin B6, bile acids and tryptophan are the most severely impaired pathways in individuals suffering from chronic mustard-induced complications. These findings may find implications in the monitoring of exposed patients and identification of new therapeutic approaches.

  20. Monitoring of DNA damage in individuals exposed to petroleum hydrocarbons in Ecuador.

    Science.gov (United States)

    Paz-y-Miño, César; López-Cortés, Andrés; Arévalo, Melissa; Sánchez, María Eugenia

    2008-10-01

    Currently, it is known that several chemical agents used or generated by the oil industry are classified as mutagens and/or carcinogens. Among these we have gasoline, diesel, butane gas, styrene, benzene, chloroform, and others. Studies have verified that these chemicals have effects in fertility (abortions, sterility); produce various upheavals, such as dizziness, nausea, muscular pain; and produce chromosomal damage at the DNA level, which in the long or medium run, can develop into cancer and leukemia. The genetic damage in exposed individuals was measured by means of the comet test, chromosomal alterations test, and the study of the CYP 1A1 and MSH2 genes. These methods were applied to determine the genotoxicity of hydrocarbons and their residue in human beings. When conducting these tests on the blood samples of individuals exposed to hydrocarbons (workers of oil companies) and of a control population of the area of study and Quito, it was found that, in effect, the exposed individuals presented a greater amount of damage at the DNA level as well as at the chromosomal level than the individuals from the control populations (Poil impact has been greater.

  1. Pupil Response to Threat in Trauma-Exposed Individuals With or Without PTSD.

    Science.gov (United States)

    Cascardi, Michele; Armstrong, Davine; Chung, Leeyup; Paré, Denis

    2015-08-01

    An infrequently studied and potentially promising physiological marker for posttraumatic stress disorder (PTSD) is pupil response. This study tested the hypothesis that pupil responses to threat would be significantly larger in trauma-exposed individuals with PTSD compared to those without PTSD. Eye-tracking technology was used to evaluate pupil response to threatening and neutral images. Recruited for participation were 40 trauma-exposed individuals; 40.0% (n = 16) met diagnostic criteria for PTSD. Individuals with PTSD showed significantly more pupil dilation to threat-relevant stimuli compared to the neutral elements (Cohen's d = 0.76), and to trauma-exposed controls (Cohen's d = 0.75). Pupil dilation significantly accounted for 12% of variability in PTSD after time elapsed since most recent trauma, cumulative violence exposure, and trait anxiety were statistically adjusted. The final logistic regression model was associated with 85% of variability in PTSD status and correctly classified 93.8% of individuals with PTSD and 95.8% of those without. Pupil reactivity showed promise as a physiological marker for PTSD.

  2. Temporal and speech processing skills in normal hearing individuals exposed to occupational noise

    Directory of Open Access Journals (Sweden)

    U Ajith Kumar

    2012-01-01

    Full Text Available Prolonged exposure to high levels of occupational noise can cause damage to hair cells in the cochlea and result in permanent noise-induced cochlear hearing loss. Consequences of cochlear hearing loss on speech perception and psychophysical abilities have been well documented. Primary goal of this research was to explore temporal processing and speech perception Skills in individuals who are exposed to occupational noise of more than 80 dBA and not yet incurred clinically significant threshold shifts. Contribution of temporal processing skills to speech perception in adverse listening situation was also evaluated. A total of 118 participants took part in this research. Participants comprised three groups of train drivers in the age range of 30-40 (n= 13, 41 50 ( = 13, 41-50 (n = 9, and 51-60 (n = 6 years and their non-noise-exposed counterparts (n = 30 in each age group. Participants of all the groups including the train drivers had hearing sensitivity within 25 dB HL in the octave frequencies between 250 and 8 kHz. Temporal processing was evaluated using gap detection, modulation detection, and duration pattern tests. Speech recognition was tested in presence multi-talker babble at -5dB SNR. Differences between experimental and control groups were analyzed using ANOVA and independent sample t-tests. Results showed a trend of reduced temporal processing skills in individuals with noise exposure. These deficits were observed despite normal peripheral hearing sensitivity. Speech recognition scores in the presence of noise were also significantly poor in noise-exposed group. Furthermore, poor temporal processing skills partially accounted for the speech recognition difficulties exhibited by the noise-exposed individuals. These results suggest that noise can cause significant distortions in the processing of suprathreshold temporal cues which may add to difficulties in hearing in adverse listening conditions.

  3. Aberrant gene promoter methylation in sputum from individuals exposed to smoky coal emissions

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Y.; Lan, Q.; Shen, M.; Jin, J.; Mumford, J.; Ren, D.X.; Keohavong, P. [University of Pittsburgh, Pittsburgh, PA (United States). Dept. of Environment and Occupational Health

    2008-07-15

    Recent studies suggested the potential for aberrant gene promoter methylation in sputum as a predictive marker for lung cancer. Here, the promoter methylation of p16, MGMT, RASSF1A and DAPK genes was investigated in sputum of individuals exposed to smoky coal emissions in Xuan Wei, China, where the lung cancer rate is more than 6 times the Chinese national average. Sputum DNA of 107 noncancer individuals and 58 lung cancer patients was screened for promoter methylation using methylation-specific PCR. Promoter methylation of the p16 gene was detected in about half (51.4% (551107)) of sputum DNA from noncancer individuals, a frequency higher than that observed for the RASSF1A (29.9%), MGMT (17.8%) and DAPK (15.9%) genes. Furthermore, the p16 gene was affected by promoter methylation at a frequency even higher among the lung cancer group, compared with the noncancer group (70.7% (41/58) versus 51.7% (55/107), p=0.017). Individuals exposed to smoky coal emissions in this region harbored frequent promoter methylation of these genes in their sputum and some of such alterations may be involved in lung tumor development.

  4. Altered activity of heme biosynthesis pathway enzymes in individuals chronically exposed to arsenic in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez-Zavala, A.; Del Razo, L.M.; Garcia-Vargas, G.G.; Aguilar, C.; Borja, V.H.; Albores, A.; Cebrian, M.E. [CINVESTAV-IPN, Mexico (Mexico). Dept. de Farmacologia y Toxicologica

    1999-03-01

    Our objective was to evaluate the activities of some enzymes of the heme biosynthesis pathway and their relationship with the profile of urinary porphyrin excretion in individuals exposed chronically to arsenic (As) via drinking water in Region Lagunera, Mexico. We selected 17 individuals from each village studied: Benito Juarez, which has current exposure to 0.3 mg As/l; Santa Ana, where individuals have been exposed for more than 35 years to 0.4 mg As/l, but due to changes in the water supply (in 1992) exposure was reduced to its current level (0.1 mg As/l), and Nazareno, with 0.014 mg As/l. Average arsenic concentrations in urine were 2058, 398, and 88 {mu}g As/g creatinine, respectively. The more evident alterations in heme metabolism observed in the highly exposed individuals were: (1) small but significant increases in porphobilinogen deaminase (PBG-D) and uroporphyrinogen decarboxylase (URO-D) activities in peripheral blood erythrocytes; (2) increases in the urinary excretion of total porphyrins, mainly due to coproporphyrin III (COPROIII) and uroporphyrin III (UROIII); and (3) increases in the COPRO/URO and COPROIII/COPROI ratios. No significant changes were observed in uroporphyrinogen III synthetase (UROIII-S) activity. The direct relationships between enzyme activities and urinary porphyrins, suggest that the increased porphyrin excretion was related to PBG-D, whereas the increased URO-D activity would enhance coproporphyrin synthesis and excretion at the expense of uroporphyrin. None of the human studies available have reported the marked porphyric response and enzyme inhibition observed in rodents. In conclusion, chronic As exposure alters human heme metabolism; however the severity of the effects appears to depend on characteristics of exposure not yet fully characterized. (orig.) With 1 fig., 3 tabs., 20 refs.

  5. Altered activity of heme biosynthesis pathway enzymes in individuals chronically exposed to arsenic in Mexico.

    Science.gov (United States)

    Hernández-Zavala, A; Del Razo, L M; García-Vargas, G G; Aguilar, C; Borja, V H; Albores, A; Cebrián, M E

    1999-03-01

    Our objective was to evaluate the activities of some enzymes of the heme biosynthesis pathway and their relationship with the profile of urinary porphyrin excretion in individuals exposed chronically to arsenic (As) via drinking water in Region Lagunera, Mexico. We selected 17 individuals from each village studied: Benito Juarez, which has current exposure to 0.3 mg As/l; Santa Ana, where individuals have been exposed for more than 35 years to 0.4 mg As/l, but due to changes in the water supply (in 1992) exposure was reduced to its current level (0.1 mg As/l), and Nazareno, with 0.014 mg As/l. Average arsenic concentrations in urine were 2058, 398, and 88 microg As/g creatinine, respectively. The more evident alterations in heme metabolism observed in the highly exposed individuals were: (1) small but significant increases in porphobilinogen deaminase (PBG-D) and uroporphyrinogen decarboxylase (URO-D) activities in peripheral blood erythrocytes; (2) increases in the urinary excretion of total porphyrins, mainly due to coproporphyrin III (COPROIII) and uroporphyrin III (UROIII); and (3) increases in the COPRO/URO and COPROIII/COPROI ratios. No significant changes were observed in uroporphyrinogen III synthetase (UROIII-S) activity. The direct relationships between enzyme activities and urinary porphyrins, suggest that the increased porphyrin excretion was related to PBG-D, whereas the increased URO-D activity would enhance coproporphyrin synthesis and excretion at the expense of uroporphyrin. None of the human studies available have reported the marked porphyric response and enzyme inhibition observed in rodents. In conclusion, chronic As exposure alters human heme metabolism; however the severity of the effects appears to depend on characteristics of exposure not yet fully characterized.

  6. A cytogenetic approach to the effects of low levels of ionizing radiations on occupationally exposed individuals

    Energy Technology Data Exchange (ETDEWEB)

    Zakeri, Farideh [National Radiation Protection Department, Iranian Nuclear Regulatory Authority, Nuclear Science and Research Institute-Agriculture, Medicine and Industry Research School, Tehran (Iran, Islamic Republic of); Graduate School of Science and Technology, Chiba University, Inage-ku, Chiba 263-8522 (Japan)], E-mail: fzakeri@aeoi.org.ir; Hirobe, Tomohisa [Graduate School of Science and Technology, Chiba University, Inage-ku, Chiba 263-8522 (Japan); Radiation Effect Mechanism Research Group, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555 (Japan)

    2010-01-15

    The aim of the present study was to assess occupationally induced chromosomal damage in hospital workers exposed to low levels of ionizing radiation. Thirty-two interventional cardiologists, 36 nuclear medicine physicians and 33 conventional radiologists were included in this study, along with 35 healthy age- and sex-matched individuals as the control group. We used conventional metaphase chromosome aberration (CA) analysis, cytokinesis-block micronucleus (MN) assay as important biological indicators of ionizing radiation exposure. Occupational dosimetry records were collected over the last year (ranged from 0.25 to 48 mSv) and their whole life exposure (ranged from 1.5 to 147 mSv). The results showed significantly higher frequencies of dicentric and acentric CAs (p < 0.001) and MN (p < 0.01) in all exposed groups than in the controls. Taking all the confounding factors into account, no obvious trend of increased chromosomal damages as a function of either duration of employment, exposed dose, sex or age was observed. Interventional cardiologists had the highest rates of CA and MN frequencies between the worker groups, though the differences were not significant. These results indicate that long term exposure to low dose ionizing radiation could result in DNA damage. Hence, the personnel who work in the hospitals should carefully apply the radiation protection procedures.

  7. The experiences and needs of individuals with disabilities exposed to chronic political violence.

    Science.gov (United States)

    Shpigelman, Carmit-Noa; Gelkopf, Marc

    2017-01-01

    Purpose The main objective of this study was to understand, describe and map the experiences, challenges and needs of individuals with lifelong disabilities, who have been exposed to chronic politically violent events (terror, war or continuous missile attacks) in Israel. Method The study was conducted within the qualitative-constructivist paradigm. Three focus groups consisting of 18 individuals with lifelong disabilities were conducted; each focus group included a specific disability type (physical, visual and hearing impairment). Results The participants reported encountering environmental barriers, such as inaccessibly of the physical environment and information as well as dependency on others. These barriers limited the participants' functioning during emergency period and thus increased their level of distress. The participants also emphasized their physical, social and psychological needs. Conclusions The needs of individuals with disabilities in emergency situations can be met if they have a safe place to stay in, are with someone else, and plan every daily action in advance. It is also imperative to provide accessible services and information. Furthermore, it is recommended to develop training sessions for individuals with disabilities and for service providers regarding how to locate, communicate with and assist individuals with disabilities during security threat situations. Implications for Rehabilitation Successful coping of individuals with lifelong disabilities with chronic politically violent events depends on personal and organizational accommodations. Besides an accessible physical environment, the information provided should be available and accessible through mass media and assistive technologies. A comprehensive emergency service for various disabilities is needed. Service providers should be trained on how to locate, communicate with, and assist individuals with disabilities during security threat situations.

  8. Biosphere Dose Conversion Factors for Reasonably Maximally Exposed Individual and Average Member of Critical Group

    Energy Technology Data Exchange (ETDEWEB)

    K. Montague

    2000-02-23

    The purpose of this calculation is to develop additional Biosphere Dose Conversion Factors (BDCFs) for a reasonably maximally exposed individual (RMEI) for the periods 10,000 years and 1,000,000 years after the repository closure. In addition, Biosphere Dose Conversion Factors for the average member of a critical group are calculated for those additional radionuclides postulated to reach the environment during the period after 10,000 years and up to 1,000,000 years. After the permanent closure of the repository, the engineered systems within the repository will eventually lose their abilities to contain radionuclide inventory, and the radionuclides will migrate through the geosphere and eventually enter the local water table moving toward inhabited areas. The primary release scenario is a groundwater well used for drinking water supply and irrigation, and this calculation takes these postulated releases and follows them through various pathways until they result in a dose to either a member of critical group or a reasonably maximally exposed individual. The pathways considered in this calculation include inhalation, ingestion, and direct exposure.

  9. Human brucellosis among pyrexia of unknown origin cases and occupationally exposed individuals in Goa Region, India

    Directory of Open Access Journals (Sweden)

    Ajay D. Pathak

    2014-04-01

    Full Text Available Background: Brucellosis is a widespread zoonotic infection. This disease is endemic in many parts of Asia, including India. Brucellosis is a major cause of pyrexia of unknown origin (PUO. Persons exposed to infected animals or contaminated animal products are at high risk. Seropositivity among animal handlers, veterinarians and dairy workers has been documented in India. Thus, the present study was aimed to determine prevalence of brucellosis among PUO cases and occupationally exposed individuals. Methods: In this study, serum samples (n=282 from cases of pyrexia of unknown origin (PUO (n=243, and occupationally exposed individuals (n=39 were collected and tested for brucellosis by Rose Bengal plate test (RBPT, serum agglutination test (SAT, indirect ELISA, IgG and IgM ELISA. Blood culture for isolation of Brucella was performed for 10 serologically positive patients using BACTEC 9050 automated blood culture system. Biochemical tests and PCR techniques were used for confirmation of the isolates. Results: Of the samples tested, 4.25%, 3.54%, 6.02% and 4.96% samples were positive by RBPT, SAT, indirect ELISA and IgG ELISA, respectively. None of the sample was positive for IgM ELISA. Of the 10 blood samples cultured bacteriologically, one Brucella isolate was recovered. The isolate was confirmed as Brucella abortus. Amplification of the bcsp31 and IS711 genes was also observed. Conclusions: Seropositivity for brucellosis was observed among PUO cases, animal handlers and dairy workers in Goa, India. The serological tests showed variable results. One Brucella isolate was obtained by performing blood culture. Confirmation of the case was done rapidly using molecular tools. General awareness about clinical symptoms should be increased which will improve proper diagnosis within short time frame.

  10. Accidentes laborales viales

    OpenAIRE

    Corzo Suárez, Susana

    2012-01-01

    El objetivo principal de este proyecto es dar a conocer la problemática de la aplicación del de la ley 31/1995, de 8 de noviembre, de Prevención de Riesgos Laborales, en la evaluación y prevención de los riesgos de los accidentes laborales viales. Para poder llegar a este objetivo se han utilizado diversas vías de estudio: Intentar aclarar qué son accidentes de tráfico y qué son accidentes laborales viales; Cuáles son los diferentes tipos de accidentes laborales viales y sus principales ca...

  11. Audiologic and otoacoustic emission evaluation in individuals exposed to noise and plaguecides

    Directory of Open Access Journals (Sweden)

    Morini, Renata Graziele

    2009-09-01

    Full Text Available Introduction: The noise induced hearing loss (NIHL has been studied for many years and today the specialized literature also studies the synergic action of chemicals. Objective: To research the audiologic findings and DPOAE in workers exposed to occupational noise and plaguecides and to compare them with data obtained in individuals without exposure to these harmful elements. Method: 51 individuals were evaluated (102 ears, divided into three groups. Group I was composed by 17 workers with exposure to noise and plaguecides, all with neurosensorial auditory loss; group II was composed by 17 workers with exposure to noise and plaguecides with audiometric thresholds within normality standards (up to 25 dBNA and group III by 17 healthy individuals without auditory alterations and without exposure to noise and plaguecides, control group. Results: In the audiologic anamnesis, as for groups I and II, we observed that the main auditory complaints presented by the workers were those of recruitment (29.5%, tinnitus (26.5%, allergy (23.5% and arterial hypertension (12%. The findings of the audiometry appointed that the research's individuals did not present with auditory losses in the frequencies of 500 Hz, 1 and 2 kHz, the losses occurred in the frequencies of 3 and 8 kHz. As for the distortion-product otoacoustic emissions (DPOAEs, we observed that the individuals in group III had a major incidence of responses when compared to those of groups I and II. Conclusion: The results analysis allowed us to conclude that the DPOAE test represents an important tool for follow up and prevention of NIHL.

  12. Air pollution and vulnerability of exposed individuals: the case of downtown Medellín

    Directory of Open Access Journals (Sweden)

    Gabriel J. González

    2012-02-01

    Full Text Available The presence of respiratory problems in high level pollution areas is linked to factors such as exposure, susceptibility, and social coping. Objective: To present statistical evidence regarding the relationship between the probability of experiencing symptoms or contracting a respiratory disease and factors such as exposure to pollution, susceptibility, and social coping among people inhabiting areas with particulate matter pollution. Methodology: The study used unique information collected from a survey conducted on 1000 people in downtown Medellin who were exposed to this problem. This information was used to perform a descriptive statistic analysis and to build 27 probit models. The dependent variables were: the patient has a symptom or disease –emf-, the patient has a symptom –leve-, and the patient has a respiratory disease –grave-. Results: The results evidence that exposure is a key variable affecting the presence of respiratory symptoms or diseases (vulnerability; however, exposed individuals may also experience health problems not only due to air pollution per se, but also to implicit personal and social conditions.

  13. Changes in serum thioredoxin among individuals chronically exposed to arsenic in drinking water

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yuanyuan; Gao, Yanhui; Zhao, Lijun [Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Hei Long Jiang Province and Ministry of Health (23618104), Harbin 150081 (China); Wei, Yudan [Department of Community Medicine, Mercer University School of Medicine, Macon 31207, GA (United States); Feng, Hongqi; Wang, Cheng; Wei, Wei; Ding, Yunpeng [Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Hei Long Jiang Province and Ministry of Health (23618104), Harbin 150081 (China); Sun, Dianjun, E-mail: hrbmusdj@163.com [Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Hei Long Jiang Province and Ministry of Health (23618104), Harbin 150081 (China)

    2012-02-15

    It is well known that oxidative damage plays a key role in the development of chronic arsenicosis. There is a complex set of mechanisms of redox cycling in vivo to protect cells from the damage. In this study, we examined the differences in the levels of serum thioredoxin1 (TRX1) among individuals exposed to different levels of arsenic in drinking water and detected early biomarkers of arsenic poisoning before the appearance of skin lesions. A total of 157 subjects from endemic regions of China were selected and divided into arsenicosis group with skin lesions (total intake of arsenic: 8.68–45.71 mg-year) and non-arsenicosis group without skin lesions, which further divided into low (0.00–1.06 mg-year), medium (1.37–3.55 mg-year), and high (4.26–48.13 mg-year) arsenic exposure groups. Concentrations of serum TRX1 were analyzed by an ELISA method. Levels of water arsenic and urinary speciated arsenics, including inorganic arsenic (iAs), monomethylated arsenic (MMA), and dimethylated arsenic (DMA), were determined by hydride generation atomic absorption spectrometry. Our results showed that the levels of serum TRX1 in arsenicosis patients were significantly higher than that of the subjects who were chronically exposed to arsenic, but without skin lesions. A positive correlation was seen between the levels of serum TRX1 and the total water arsenic intake or the levels of urinary arsenic species. The results of this study indicate that arsenic exposure could significantly change the levels of human serum TRX1, which can be detected before arsenic-specific dermatological symptoms occur. This study provides further evidence on revealing the mechanism of arsenic toxicity. -- Highlights: ► Three regions are selected as the areas affected by endemic arsenicosis of China. ► We first examine changes in serum TRX1 among individuals exposed to arsenic. ► A positive correlation was seen between serum TRX1 and total water arsenic intake. ► The same relationship

  14. Potent neutralizing serum immunoglobulin A (IgA) in human immunodeficiency virus type 2-exposed IgG-seronegative individuals

    DEFF Research Database (Denmark)

    Lizeng, Q; Nilsson, C; Sourial, S;

    2004-01-01

    Links Potent neutralizing serum immunoglobulin A (IgA) in human immunodeficiency virus type 2-exposed IgG-seronegative individuals.Lizeng Q, Nilsson C, Sourial S, Andersson S, Larsen O, Aaby P, Ehnlund M, Bjorling E. Research Center, South Hospital, Stockholm, Sweden. The mechanisms behind...... the resistance to human immunodeficiency virus type 2 (HIV-2) infection are still not fully understood. In the present study, we explored the HIV-2-specific humoral serum immunoglobulin A (IgA) immune response in HIV-2-exposed IgG-seronegative (EGSN) individuals. Serum samples from heterosexual EGSN individuals...

  15. Accidental Bowel Leakage

    Science.gov (United States)

    ... I do to help treat accidental bowel leakage? Kegel exercises strengthen the muscles that surround the openings ... bowels that may cause cramping, diarrhea, or constipation. Kegel Exercises: Pelvic muscle exercises that assist in bladder ...

  16. Retrospective genetic study of germinative mutations in Str loci of individuals potentially exposed to ionizing radiation;Estudo genetico retrospectivo de mutacoes germinativas em Loci Str de individuos potencialmente expostos a radiacao ionizante

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Emilia Oliveira Alves

    2010-07-01

    The Brazilian radiological accident that occurred in 1987, in Goiania, it was a terrible radiation episode. As a consequence, hundreds of people were contaminated due to the Cesium-137 radiation. Recently, many studies had shown that genome instabilities, such as, mutations, chromosomal aberrations, micronuclei formation and micro satellite instability and a delay on cellular death are usually reported on mammal cells exposed to ionizing radiation, being considered as a manly risk to humans. Mutations can be spontaneous, and the occurrence is dependent on the organism, or, induced, being associated to mutagenic exposition. Ionizing radiations are an example of physical and mutagenic agents that could harm the cell repair and could cause the development of many types of cancer. The evaluation of the biological effects of the ionizing radiation, in somatic and germ line cells, with a consequent determination of the radio-induced mutations, it is extremely important to estimate the genetic risks, manly in population exposed to radiation. The analyses of repetitive DNA sequences have been demonstrated that such sequences are prone to high rates of spontaneous mutations. The minisatellites and microsatellites have been used to demonstrate the induction of germ line mutation rates on mouse, humans, among others organisms. The aim of the present study was to analyze the frequency of microsatellite alterations to determine the mutation rates occurred in germ cells of the parents exposed to the ionizing radiation of the Cesium-137. The studied group was constitute of 10 families of individuals accidentally exposed to Cesium-137 and by the control group constituted by 645 healthy individuals who carried out paternity tests on 2009. We found only one mutation of paternal origin in the D8S1179 locus on the exposed group, being the mutation rate of 0.002. In the control group, we found 01 mutation on D16S539 loei and on D3S1358; 02 mutations on Penta E loeus; 04 mutations on D

  17. p21(WAF1/CIP1 RNA expression in highly HIV-1 exposed, uninfected individuals.

    Directory of Open Access Journals (Sweden)

    Joshua Herbeck

    Full Text Available Some individuals remain HIV-1 antibody and PCR negative after repeated exposures to the virus, and are referred to as HIV-exposed seronegatives (HESN. However, the causes of resistance to HIV-1 infection in cases other than those with a homozygous CCR5Δ32 deletion are unclear. We hypothesized that human p21WAF1/CIP1 (a cyclin-dependent kinase inhibitor could play a role in resistance to HIV-1 infection in HESN, as p21 expression has been associated with suppression of HIV-1 in elite controllers and reported to block HIV-1 integration in cell culture. We measured p21 RNA expression in PBMC from 40 HESN and 40 low exposure HIV-1 seroconverters (LESC prior to their infection using a real-time PCR assay. Comparing the 20 HESN with the highest exposure risk (median = 111 partners/2.5 years prior to the 20 LESC with the lowest exposure risk (median = 1 partner/2.5 years prior, p21 expression trended higher in HESN in only one of two experiments (P = 0.11 vs. P = 0.80. Additionally, comparison of p21 expression in the top 40 HESN (median = 73 partners/year and lowest 40 LESC (median = 2 partners/year showed no difference between the groups (P = 0.84. There was a weak linear trend between risk of infection after exposure and increasing p21 gene expression (R2 = 0.02, P = 0.12, but again only in one experiment. Hence, if p21 expression contributes to the resistance to viral infection in HESN, it likely plays a minor role evident only in those with extremely high levels of exposure to HIV-1.

  18. Panic symptoms and elevated suicidal ideation and behaviors among trauma exposed individuals: Moderating effects of post-traumatic stress disorder.

    Science.gov (United States)

    Albanese, Brian J; Norr, Aaron M; Capron, Daniel W; Zvolensky, Michael J; Schmidt, Norman B

    2015-08-01

    Panic attacks (PAs) are highly prevalent among trauma exposed individuals and have been associated with a number of adverse outcomes. Despite high suicide rates among trauma exposed individuals, research to date has not examined the potential relation between panic symptoms and suicidal ideation and behaviors among this high risk population. The current study tested the association of panic with suicidal ideation and behaviors among a large sample of trauma exposed smokers. Community participants (N=421) who reported a lifetime history of trauma exposure were assessed concurrently for current panic, suicidal ideation and behaviors, and psychiatric diagnoses. Those who met criteria for a current panic disorder diagnosis were removed from analyses to allow for the assessment of non-PD related panic in line with the recent addition of the PA specifier applicable to all DSM-5 disorders. Findings indicated that panic symptoms were significantly associated with suicidal ideation and behaviors beyond the effects of depression and number of trauma types experienced. Further, post-traumatic stress disorder (PTSD) diagnostic status significantly moderated this relationship, indicating that the relationship between panic and suicidal ideation and behaviors is potentiated among individuals with a current PTSD diagnosis. This investigation suggests that panic symptoms may be a valuable clinical target for the assessment and treatment of suicidal ideation and behaviors among trauma exposed individuals.

  19. Radiative accidental matter

    CERN Document Server

    Sierra, D Aristizabal; Wegman, D

    2016-01-01

    Accidental matter models are scenarios where the beyond-the-standard model physics preserves all the standard model accidental and approximate symmetries up to a cutoff scale related with lepton number violation. We study such scenarios assuming that the new physics plays an active role in neutrino mass generation, and show that this unavoidably leads to radiatively induced neutrino masses. We systematically classify all possible models and determine their viability by studying electroweak precision data, big bang nucleosynthesis and electroweak perturbativity, finding that the latter places the most stringent constraints on the mass spectra. These results allow the identification of minimal radiative accidental matter models for which perturbativity is lost at high scales. We calculate radiative charged-lepton flavor violating processes in these setups, and show that $\\mu\\to e \\gamma$ has a rate well within MEG sensitivity provided the lepton-number violating scale is at or below $10^6\\,$ GeV, a value (natur...

  20. Causes of accidental childhood deaths in China in 2010

    DEFF Research Database (Denmark)

    Chan, Kit Yee; Yu, Xin-Wei; Lu, Jia-Peng

    2015-01-01

    BACKGROUND: Infectious causes of childhood deaths in the world have decreased substantially in the 21st century. This trend has exposed accidental deaths as an increasingly important future challenge. Presently, little is known about the cause structure of accidental childhood deaths in low......- and middle-income country (LMIC) settings. In this paper, we aim to establish cause structure for accidental deaths in children aged 0-4 years in China in the year 2010. METHODS: In this paper, we explored the database of 208 multi-cause child mortality studies in Chinese that formed a basis for the first...... published estimate of the causes of child deaths in China (for the year 2008). Only five of those studies identified specific causes of accidental deaths. Because of this, we searched the Chinese medical literature databases CNKI and WanFang for single-cause mortality studies that were focused on accidental...

  1. Elevated brain aluminium and early onset Alzheimer’s disease in an individual occupationally exposed to aluminium: a case report

    OpenAIRE

    2014-01-01

    Introduction Aluminium is a known neurotoxin and occupational exposure to aluminium has been implicated in neurological disease including Alzheimer’s disease. Here we present the first comprehensive and unequivocal data demonstrating significantly elevated brain aluminium content in an individual occupationally exposed to aluminium. Case presentation A 66-year-old Caucasian man who died with Alzheimer’s disease showed significantly elevated brain aluminium content, 2.98 (2.73) μg/g dry weight...

  2. Determinants of active and environmental exposure to tobacco smoke and upper reference value of urinary cotinine in not exposed individuals.

    Science.gov (United States)

    Campo, Laura; Polledri, Elisa; Bechtold, Petra; Gatti, Giulia; Ranzi, Andrea; Lauriola, Paolo; Goldoni, Carlo Alberto; Bertazzi, Pier Alberto; Fustinoni, Silvia

    2016-07-01

    The aims of this study were (1) to explore the behavioral and sociodemographic factors influencing urinary cotinine (COT-U) levels in active smokers and in environmental tobacco smoke (ETS)-exposed individuals, (2) to assess the specificity and sensitivity of the questionnaire for identifying active smokers and nonsmokers, and (3) to derive the upper reference value of COT-U in non-ETS exposed individuals. The COT-U levels of 495 adults (age range 18-69 years) who classified themselves as active smokers (29%) or as nonsmokers with (17%) or without (83%) ETS exposure were quantified by LC-MS-MS (quantification limit: 0.1µg/L, range of linearity: 0.1-4000µg/L). Median COT-U levels in these groups were 883, 1.38, and 0.39µg/L, respectively. Significant determinants of COT-U levels in active smokers were the number of cigarettes per day, type of smoking product, smoking environment, as well as time between the last cigarette and urine collection. Among ETS-exposed nonsmokers, significant determinants were living with smokers, being exposed to smoke at home, ETS exposure duration, as well as time between the last exposure and urine collection. When a 30-µg/L COT-U cut-off value was used to identify active daily smoking, the sensitivity and specificity of the questionnaire were 94% and 98%, respectively. For ETS exposure, the COT-U value of 1.78 (0.90 confidence interval 1.75-1.78) µg/L, corresponding to the 95th percentiles of the COT-U distribution in non-ETS-exposed participants, is proposed as upper reference value to identify environmental exposure.

  3. Intranasal Oxytocin Affects Amygdala Functional Connectivity after Trauma Script-Driven Imagery in Distressed Recently Trauma-Exposed Individuals.

    Science.gov (United States)

    Frijling, Jessie L; van Zuiden, Mirjam; Koch, Saskia B J; Nawijn, Laura; Veltman, Dick J; Olff, Miranda

    2016-04-01

    Approximately 10% of trauma-exposed individuals go on to develop post-traumatic stress disorder (PTSD). Neural emotion regulation may be etiologically involved in PTSD development. Oxytocin administration early post-trauma may be a promising avenue for PTSD prevention, as intranasal oxytocin has previously been found to affect emotion regulation networks in healthy individuals and psychiatric patients. In a randomized double-blind placebo-controlled between-subjects functional magnetic resonance (fMRI) study, we assessed the effects of a single intranasal oxytocin administration (40 IU) on seed-based amygdala resting-state FC with emotion regulation areas (ventromedial prefrontal cortex (vmPFC), ventrolateral prefrontal cortex (vlPFC)), and salience processing areas (insula, dorsal anterior cingulate cortex (dACC)) in 37 individuals within 11 days post trauma. Two resting-state scans were acquired; one after neutral- and one after trauma-script-driven imagery. We found that oxytocin administration reduced amygdala-left vlPFC FC after trauma script-driven imagery, compared with neutral script-driven imagery, whereas in PL-treated participants enhanced amygdala-left vlPFC FC was observed following trauma script-driven imagery. Irrespective of script condition, oxytocin increased amygdala-insula FC and decreased amygdala-vmPFC FC. These neural effects were accompanied by lower levels of sleepiness and higher flashback intensity in the oxytocin group after the trauma script. Together, our findings show that oxytocin administration may impede emotion regulation network functioning in response to trauma reminders in recently trauma-exposed individuals. Therefore, caution may be warranted in administering oxytocin to prevent PTSD in distressed, recently trauma-exposed individuals.

  4. Health care workers and AIDS: a differential study of beliefs and affects associated with accidental exposure to blood

    Directory of Open Access Journals (Sweden)

    Maria Rosa Rodrigues Rissi

    Full Text Available This study aimed to analyze affective and cognitive determinants of the professional work of individuals caring for patients with HIV/AIDS, in view of the risk and/or experience of accidental exposure to blood. We drew on the theoretical-methodological references of Fishbein & Ajzen and Maslow's theory. Fifty health care workers were evaluated using an attitudes questionnaire and a needs and motivations instrument. The research verified differences between answers by health care workers who had never suffered accidents and those who had already experienced accidental exposure to blood. Health care workers did their work activities motivated by the need for self-fulfillment and valued their own performance when they were able to meet the patients' emotional needs. Among health professionals who had never experienced accidental exposure to blood, the predominant beliefs was that patients feel remorse over having expose themselves to HIV. Accidental exposure to blood raises difficulties in personal life. Technical aspects are also associated with the possibility of accidental exposure to blood.

  5. Health care workers and AIDS: a differential study of beliefs and affects associated with accidental exposure to blood.

    Science.gov (United States)

    Rissi, Maria Rosa Rodrigues; Machado, Alcyone Artioli; Figueiredo, Marco Antonio de Castro

    2005-01-01

    This study aimed to analyze affective and cognitive determinants of the professional work of individuals caring for patients with HIV/AIDS, in view of the risk and/or experience of accidental exposure to blood. We drew on the theoretical-methodological references of Fishbein & Ajzen and Maslow's theory. Fifty health care workers were evaluated using an attitudes questionnaire and a needs and motivations instrument. The research verified differences between answers by health care workers who had never suffered accidents and those who had already experienced accidental exposure to blood. Health care workers did their work activities motivated by the need for self-fulfillment and valued their own performance when they were able to meet the patients' emotional needs. Among health professionals who had never experienced accidental exposure to blood, the predominant beliefs was that patients feel remorse over having expose themselves to HIV. Accidental exposure to blood raises difficulties in personal life. Technical aspects are also associated with the possibility of accidental exposure to blood.

  6. Assessment of the relative success of sporozoite inoculations in individuals exposed to moderate seasonal transmission

    Directory of Open Access Journals (Sweden)

    Spiegel André

    2009-07-01

    Full Text Available Abstract Background The time necessary for malaria parasite to re-appear in the blood following treatment (re-infection time is an indirect method for evaluating the immune defences operating against pre-erythrocytic and early erythrocytic malaria stages. Few longitudinal data are available in populations in whom malaria transmission level had also been measured. Methods One hundred and ten individuals from the village of Ndiop (Senegal, aged between one and 72 years, were cured of malaria by quinine (25 mg/day oral Quinimax™ in three equal daily doses, for seven days. Thereafter, thick blood films were examined to detect the reappearance of Plasmodium falciparum every week, for 11 weeks after treatment. Malaria transmission was simultaneously measured weekly by night collection of biting mosquitoes. Results Malaria transmission was on average 15.3 infective bites per person during the 77 days follow up. The median reappearance time for the whole study population was 46.8 days, whereas individuals would have received an average one infective bite every 5 days. At the end of the follow-up, after 77 days, 103 of the 110 individuals (93.6%; CI 95% [89.0–98.2] had been re-infected with P. falciparum. The median reappearance time ('re-positivation' was longer in subjects with patent parasitaemia at enrolment than in parasitologically-negative individuals (58 days vs. 45.9; p = 0.03 and in adults > 30 years than in younger subjects (58.6 days vs. 42.7; p = 0.0002. In a multivariate Cox PH model controlling for the sickle cell trait, G6PD deficiency and the type of habitat, the presence of parasitaemia at enrolment and age ≥ 30 years were independently predictive of a reduced risk of re-infection (PH = 0.5 [95% CI: 0.3–0.9] and 0.4; [95% CI: 0.2–0.6] respectively. Conclusion Results indicate the existence of a substantial resistance to sporozoites inoculations, but which was ultimately overcome in almost every individual after 2 1/2 months of

  7. Individual differences and repeatability in vocal production: stress-induced calling exposes a songbird's personality

    Science.gov (United States)

    Guillette, Lauren M.; Sturdy, Christopher B.

    2011-11-01

    Recent research in songbirds has demonstrated that male singing behavior varies systematically with personality traits such as exploration and risk taking. Here we examine whether the production of bird calls, in addition to bird songs, is repeatable and related to exploratory behavior, using the black-capped chickadee ( Poecile atricapillus) as a model. We assessed the exploratory behavior of individual birds in a novel environment task. We then recorded the vocalizations and accompanying motor behavior of both male and female chickadees, over the course of several days, in two different contexts: a control condition with no playback and a stressful condition where chick-a-dee mobbing calls were played to individual birds. We found that several vocalizations and behaviors were repeatable within both a control and a stressful context, and across contexts. While there was no relationship between vocal output and exploratory behavior in the control context, production of alarm and chick-a-dee calls in the stressful condition was positively associated with exploratory behavior. These findings are important because they show that bird calls, in addition to bird song, are an aspect of personality, in that calls are consistent both within and across contexts, and covary with other personality measures (exploration).

  8. Diagnostic assessment to estimate and minimize neutron dose rates received by occupationally exposed individuals at cyclotron facilities

    Energy Technology Data Exchange (ETDEWEB)

    Reina, L.C. [Instituto de Engenharia Nuclear, Comissao Nacional de Energia Nuclear, Caixa Postal 68550, Cidade Universitaria, CEP: 21941-906 Rio de Janeiro (Brazil)], E-mail: reina@ien.gov.br; Silva, A.X. [PEN/COPPE-DNC/Escola Politecnica, Universidade Federal do Rio de Janeiro, Cidade Universitaria, CEP: 21945-970 Rio de Janeiro (Brazil); Suita, J.C.; Souza, M.I.S. [Instituto de Engenharia Nuclear, Comissao Nacional de Energia Nuclear, Caixa Postal 68550, Cidade Universitaria, CEP: 21941-906 Rio de Janeiro (Brazil); Facure, A. [Comissao Nacional de Energia Nuclear Rua General Severiano, 90-Botafogo, CEP: 22290-901 Rio de Janeiro (Brazil); Silva, J.C.P.; Furlanetto, J.A.D. [Instituto de Engenharia Nuclear, Comissao Nacional de Energia Nuclear, Caixa Postal 68550, Cidade Universitaria, CEP: 21941-906 Rio de Janeiro (Brazil); Rebello, W. [Instituto Militar de Engenharia, Ministerio da Defesa Praca General Tiburcio, 80-Praia Vermelha, CEP: 22290-270 Rio de Janeiro (Brazil)

    2010-03-15

    Since 2003, radiopharmaceuticals for medical diagnostic purposes have been produced at the Instituto de Engenharia Nuclear, in Brazil, using two cyclotron accelerators - CV-28 and RDS111. As a result of the ever increasing production, a diagnostic assessment to reduce neutron dose rates received by occupationally exposed individuals during irradiation processes has been developed. The purpose of this work is to present this assessment, which is currently being applied to both the Fluorine and Iodine targets of CV-28 and RDS111 cyclotron accelerators.

  9. Flavour from accidental symmetries

    Energy Technology Data Exchange (ETDEWEB)

    Ferretti, Luca [SISSA/ISAS and INFN, I-34013 Trieste (Italy); King, Stephen F. [School of Physics and Astronomy, University of Southampton, Southampton, SO17 1BJ (United Kingdom); Romanino, Andrea [SISSA/ISAS and INFN, I-34013 Trieste (Italy)

    2006-11-15

    We consider a new approach to fermion masses and mixings in which no special 'horizontal' dynamics is invoked to account for the hierarchical pattern of charged fermion masses and for the peculiar features of neutrino masses. The hierarchy follows from the vertical, family-independent structure of the model, in particular from the breaking pattern of the Pati-Salam group. The lightness of the first two fermion families can be related to two family symmetries emerging in this context as accidental symmetries.

  10. [Doping in endurance sports. Survey of individual [Hb] levels can expose doping].

    Science.gov (United States)

    Ekblom, B; Holmberg, H C; Eriksson, K

    2001-11-28

    Doping through increasing [Hb] increases physical performance in sport. Therefore, no cross-country skiers with [Hb] values above 160 and 175 g/l for women and men, respectively, may start in competitions. Even plasma expanders have been used, possibly for lowering a high [Hb] but this procedure may not increase physical performance. There are methods available for detecting the use of erythropoietin but not reinfusion of erythrocytes to increase [Hb]. To make it more difficult to increase [Hb] by different unethical methods we suggest that the [Hb] in endurance athletes is determined both during the training and the competition season to establish individual [Hb] mean values and range. Since endurance training at altitude does not increase [Hb] after return to sea level, an occasional increased [Hb] is suspicious. In such a case complementary doping tests may be used.

  11. Investigation of implicit avoidance of displacement-related stimuli in offspring of trauma exposed, forcibly-displaced individuals.

    Science.gov (United States)

    Wittekind, Charlotte E; Muhtz, Christoph; Moritz, Steffen; Jelinek, Lena

    2017-02-03

    There is an ongoing debate as to whether traumatization also affects the close relatives of trauma survivors who have symptoms of PTSD. Although many studies provide evidence favoring a transgenerational transmission, other studies have not found evidence to support this idea. The present study examined whether adult offspring of individuals exposed to trauma during forced displacement with (n=22) and without PTSD (n=24) exhibit an implicit avoidance of stimuli related to the parental trauma compared to children of non-trauma exposed control participants (n=23) using an Approach-Avoidance task (AAT). Offspring participants were requested to push (i.e., avoidance) or pull (i.e., approach) displacement-related and neutral pictures, whereby response direction depended on a non-affective dimension (color of the pictures). Results suggest that the offspring of non-PTSD participants exhibit implicit avoidance of displacement-related stimuli. This rather unexpected finding might either indicate resilience amongst offspring of PTSD participants or that offspring of non-PTSD participants are particularly affected. If these results were to replicate, they suggest that implicit avoidance tendencies amongst the offspring of trauma exposed participants might partially contribute to their heightened PTSD vulnerability. Longitudinal studies are needed to elucidate whether implicit avoidance tendencies are associated with increased stress vulnerability.

  12. DNA damage in leukocytes, buccal cells and nasal epithelial cells of individuals exposed to air pollution in Mexico City

    Energy Technology Data Exchange (ETDEWEB)

    Valverde, M.; Lopez, M.C.; Ostrosky-Wegman, P. [and others

    1997-10-01

    There is an increased interest in using biological markers to monitor populations for the identification of exposure to environmental toxicants. Test systems which permit the sensitive detection of DNA damage and DNA repair are critically important. The single cell gel electrophoresis assay is a rapid and a sensitive method for the evaluation of DNA damage at the single cell level ant it provides information on the occurrence of DNA single-strand breaks and alkali labile sites using alkaline conditions. In this work, the differences in the basal level of DNA single strand breaks using alkaline single strand breaks using alkaline single cell gel electrophoresis, between young adults from the south (exposed principally to high levels of ozone) and north (exposed principally to hydrocarbons and particles) of Mexico City was investigated using three different cell types (leukocytes, nasal and buccal epithelial cells). We found an increased DNA tail length in blood and nasal cells from individuals who live in the south part of the city compared to the northern part. However, no differences were observed in buccal epithelial cells. These results show the feasibility of using SCGE in different tissues and its great potential for the monitoring of humans exposed to xenobiotics.

  13. Antibodies and immune profiles of individuals occupationally exposed to formaldehyde: six case reports.

    Science.gov (United States)

    Thrasher, J D; Broughton, A; Micevich, P

    1988-01-01

    Six patients with multiple subjective health complaints, which have been correlated with chronic exposure to formaldehyde during the course of their education and occupations, were tested for the existence of antibodies (IgE, IgM, and IgG) to formaldehyde (F) conjugated to human serum albumin (F-HSA). In addition, the percentage and absolute numbers of peripheral lymphocyte subpopulations as determined by surface markers were investigated. Antibody titers to F-HSA were present as follows: IgE (2 patients), IgM (3 of 4 tested patients), and IgG (5 patients). Analysis of lymphocyte subpopulations showed T-helper/suppressor (H/S) ratios ranging from 0.8 to 3.3. All 6 patients had elevated Tal cells (antigen memory cells), whereas interleuken 2 receptor positive cells were within expected values. Following formaldehyde exposure, 5 of the patients complained of an initial flulike illness from which they have not completely recovered. The sixth individual had a history of recurrent respiratory infections and surgical removal of hyperplastic ethmoid sinus tissue. The common occurrence of anti-F-HSA antibodies, flulike illness, and Tal cells are interpreted as suggestive of a chronic antigenic stimulation of the immune system in these 6 patients. Further immunological work-up of additional subjects and immune parameters with similar history of formaldehyde exposure and subjective health complaints is warranted.

  14. Partial protective effect of CCR5-Delta 32 heterozygosity in a cohort of heterosexual Italian HIV-1 exposed uninfected individuals

    Directory of Open Access Journals (Sweden)

    Cauda Roberto

    2006-09-01

    Full Text Available Abstract Despite multiple sexual exposure to HIV-1 virus, some individuals remain HIV-1 seronegative (exposed seronegative, ESN. The mechanisms underlying this resistance remain still unclear, although a multifactorial pathogenesis can be hypothesised. Although several genetic factors have been related to HIV-1 resistance, the homozigosity for a mutation in CCR5 gene (the 32 bp deletion, i.e. CCR5-Delta32 allele is presently considered the most relevant one. In the present study we analysed the genotype at CCR5 locus of 30 Italian ESN individuals (case group who referred multiple unprotected heterosexual intercourse with HIV-1 seropositive partner(s, for at least two years. One hundred and twenty HIV-1 infected patients and 120 individuals representative of the general population were included as control groups. Twenty percent of ESN individuals had heterozygous CCR5-Delta 32 genotype, compared to 7.5% of HIV-1 seropositive and 10% of individuals from the general population, respectively. None of the analysed individuals had CCR5-Delta 32 homozygous genotype. Sequence analysis of the entire open reading frame of CCR5 was performed in all ESN subjects and no polymorphisms or mutations were identified. Moreover, we determined the distribution of C77G variant in CD45 gene, which has been previously related to HIV-1 infection susceptibility. The frequency of the C77G variant showed no significant difference between ESN subjects and the two control groups. In conclusion, our data show a significantly higher frequency of CCR5-Delta 32 heterozygous genotype (p = 0.04 among the Italian heterosexual ESN individuals compared to HIV-1 seropositive patients, suggesting a partial protective role of CCR5-Delta 32 heterozygosity in this cohort.

  15. In vivo monitoring of occupationally exposed individuals to {sup 18}FDG in CRCN/NE; Monitoracao in vivo dos individuos ocupacionalmente expostos na producao de {sup 18}FDG no CRCN/NE

    Energy Technology Data Exchange (ETDEWEB)

    Lacerda, I.V.B. [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil); Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Programa de Pos-Graduacao em Tecnologias Energeticas e Nucleares; Xavier, A.C.S.; Oliveira, M.L.; Lima, F.F.; Lima, F.R.A., E-mail: bellelacerda@hotmail.com [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil)

    2012-07-01

    The increasing demand for PET radiopharmaceuticals in Brazil results in increasing of the number of occupationally exposed individuals (OEI) to the radiopharmaceutical {sup 18}F in the form of {sup 18}FDG, increasing thereby the risk of accidental incorporation. This work aims to implement an in vivo internal monitoring technique applied to {sup 18}FDG radiopharmaceutical at the Divisao de Producao de Radiofarmacos (DIPRA) of the Centro Regional de Ciencias Nucleares do Nordeste (CRCN/NE). The detection system used was a NaI(Tl) 3'' x 3'' detector connected to a compact electronic module operated by the Genie 2000 software. It was calibrated using a brain phantom containing a standard source of {sup 22}Na which simulates a contaminated individual. Based on the calibration factor it was possible to determine the minimum detectable activity (MDA) of the detection system and then, through use of biokinetic models provided by the ICRP in its publication 53 and edited by the AIDE version 6.0 software, it was possible to calculate the minimum detectable effective dose (MDED) which is an indication of the technique sensitivity. The MDED was estimated for the in vivo measurements performed up to 0.1 day after the occurrence of an intake by ingestion. The value obtained was compared to the Recording level of 1 mSv recommended by the IAEA. After validation of the in vivo monitoring technique, a series of measurements were performed on a group of occupationally exposed workers from DIPRA shortly after completion of production and quality control of {sup 18}FDG radiopharmaceutical procedures. It is concluded that the proposed technique is sufficiently sensitive for its application in internal occupational monitoring. (author)

  16. Behavioural and physiological responses of Gammarus pulex exposed to cadmium and arsenate at three temperatures: individual and combined effects.

    Directory of Open Access Journals (Sweden)

    Céline Vellinger

    Full Text Available This study aimed at investigating both the individual and combined effects of cadmium (Cd and arsenate (AsV on the physiology and behaviour of the Crustacean Gammarus pulex at three temperatures (5, 10 and 15 °C. G. pulex was exposed during 96 h to (i two [Cd] alone, (ii two [AsV] alone, and (iii four combinations of [Cd] and [AsV] to obtain a complete factorial plane. After exposure, survival, [AsV] or [Cd] in body tissues, behavioural (ventilatory and locomotor activities and physiological responses (iono-regulation of [Na(+] and [Cl(-] in haemolymph were examined. The interactive effects (antagonistic, additive or synergistic of binary mixtures were evaluated for each tested temperature using a predictive model for the theoretically expected interactive effect of chemicals. In single metal exposure, both the internal metal concentration in body tissues and the mortality rate increased along metallic gradient concentration. Cd alone significantly impaired both [Na(+] and [Cl(-] while AsV alone had a weak impact only on [Cl(-]. The behavioural responses of G. pulex declined with increasing metal concentration suggesting a reallocation of energy from behavioural responses to maintenance functions. The interaction between AsV and Cd was considered as 'additive' for all the tested binary mixtures and temperatures (except for the lowest combination at 10 °C considered as "antagonistic". In binary mixtures, the decrease in both ventilatory and locomotor activities and the decline in haemolymphatic [Cl(-] were amplified when respectively compared to those observed with the same concentrations of AsV or Cd alone. However, the presence of AsV decreased the haemolymphatic [Na(+] loss when G. pulex was exposed to the lowest Cd concentration. Finally, the observed physiological and behavioural effects (except ventilation in G. pulex exposed to AsV and/or Cd were exacerbated under the highest temperature. The discussion encompasses both the toxicity

  17. Accidental dapsone poisoning in children.

    Science.gov (United States)

    Nair, P M; Philip, E

    1984-12-01

    Accidental poisoning in children shows a trend towards poisoning with various newer drugs and chemicals used in the household. Sixty-one cases of accidental poisoning in children were seen in Sree Avittam Thirunal Hospital, (S.A.T.H.), Trivandrum, South India during the year 1982, constituting 0.61% of the total pediatric admissions. Dapsone poisoning constituted 9.8% of the total accidental poisonings, emphasising the need for safe storage of drugs out of the reach of young children. Dapsone poisoning with resultant methaemoglobinaemia responded well to intravenous ascorbic acid and other supportive measures.

  18. Comprehensive analysis of 5-aminolevulinic acid dehydrogenase (ALAD variants and renal cell carcinoma risk among individuals exposed to lead.

    Directory of Open Access Journals (Sweden)

    Dana M van Bemmel

    Full Text Available BACKGROUND: Epidemiologic studies are reporting associations between lead exposure and human cancers. A polymorphism in the 5-aminolevulinic acid dehydratase (ALAD gene affects lead toxicokinetics and may modify the adverse effects of lead. METHODS: The objective of this study was to evaluate single-nucleotide polymorphisms (SNPs tagging the ALAD region among renal cancer cases and controls to determine whether genetic variation alters the relationship between lead and renal cancer. Occupational exposure to lead and risk of cancer was examined in a case-control study of renal cell carcinoma (RCC. Comprehensive analysis of variation across the ALAD gene was assessed using a tagging SNP approach among 987 cases and 1298 controls. Occupational lead exposure was estimated using questionnaire-based exposure assessment and expert review. Odds ratios (OR and 95% confidence intervals (CI were calculated using logistic regression. RESULTS: The adjusted risk associated with the ALAD variant rs8177796(CT/TT was increased (OR = 1.35, 95%CI = 1.05-1.73, p-value = 0.02 when compared to the major allele, regardless of lead exposure. Joint effects of lead and ALAD rs2761016 suggest an increased RCC risk for the homozygous wild-type and heterozygous alleles ((GGOR = 2.68, 95%CI = 1.17-6.12, p = 0.01; (GAOR = 1.79, 95%CI = 1.06-3.04 with an interaction approaching significance (p(int = 0.06. No significant modification in RCC risk was observed for the functional variant rs1800435(K68N. Haplotype analysis identified a region associated with risk supporting tagging SNP results. CONCLUSION: A common genetic variation in ALAD may alter the risk of RCC overall, and among individuals occupationally exposed to lead. Further work in larger exposed populations is warranted to determine if ALAD modifies RCC risk associated with lead exposure.

  19. Cellular responses to modified Plasmodium falciparum MSP119 antigens in individuals previously exposed to natural malaria infection

    Directory of Open Access Journals (Sweden)

    Awobode Henrietta O

    2009-11-01

    Full Text Available Abstract Background MSP1 processing-inhibitory antibodies bind to epitopes on the 19 kDa C-terminal region of the Plasmodium falciparum merozoite surface protein 1 (MSP119, inhibiting erythrocyte invasion. Blocking antibodies also bind to this antigen but prevent inhibitory antibodies binding, allowing invasion to proceed. Recombinant MSP119 had been modified previously to allow inhibitory but not blocking antibodies to continue to bind. Immunization with these modified proteins, therefore, has the potential to induce more effective protective antibodies. However, it was unclear whether the modification of MSP119 would affect critical T-cell responses to epitopes in this antigen. Methods The cellular responses to wild-type MSP119 and a panel of modified MSP119 antigens were measured using an in-vitro assay for two groups of individuals: the first were malaria-naïve and the second had been naturally exposed to Plasmodium falciparum infection. The cellular responses to the modified proteins were examined using cells from malaria-exposed infants and adults. Results Interestingly, stimulation indices (SI for responses induced by some of the modified proteins were at least two-fold higher than those elicited by the wild-type MSP119. A protein with four amino acid substitutions (Glu27→Tyr, Leu31→Arg, Tyr34→Ser and Glu43→Leu had the highest stimulation index (SI up to 360 and induced large responses in 64% of the samples that had significant cellular responses to the modified proteins. Conclusion This study suggests that specific MSP119 variants that have been engineered to improve their antigenicity for inhibitory antibodies, retain T-cell epitopes and the ability to induce cellular responses. These proteins are candidates for the development of MSP1-based malaria vaccines.

  20. Allegheny County Fatal Accidental Overdoses

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Fatal accidental overdose incidents in Allegheny County, denoting age, gender, race, drugs present, zip code of incident and zip code of residence. Zip code of...

  1. Elevated levels of plasma Big endothelin-1 and its relation to hypertension and skin lesions in individuals exposed to arsenic

    Energy Technology Data Exchange (ETDEWEB)

    Hossain, Ekhtear; Islam, Khairul; Yeasmin, Fouzia [Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi-6205 (Bangladesh); Karim, Md. Rezaul [Department of Applied Nutrition and Food Technology, Islamic University, Kushtia-7003 (Bangladesh); Rahman, Mashiur; Agarwal, Smita; Hossain, Shakhawoat; Aziz, Abdul; Al Mamun, Abdullah; Sheikh, Afzal; Haque, Abedul; Hossain, M. Tofazzal [Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi-6205 (Bangladesh); Hossain, Mostaque [Department of Medicine, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka (Bangladesh); Haris, Parvez I. [Faculty of Health and Life Sciences, De Montfort University, Leicester, LE1 9BH (United Kingdom); Ikemura, Noriaki; Inoue, Kiyoshi; Miyataka, Hideki; Himeno, Seiichiro [Laboratory of Molecular Nutrition and Toxicology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770–8514 (Japan); Hossain, Khaled, E-mail: khossain69@yahoo.com [Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi-6205 (Bangladesh)

    2012-03-01

    Chronic arsenic (As) exposure affects the endothelial system causing several diseases. Big endothelin-1 (Big ET-1), the biological precursor of endothelin-1 (ET-1) is a more accurate indicator of the degree of activation of the endothelial system. Effect of As exposure on the plasma Big ET-1 levels and its physiological implications have not yet been documented. We evaluated plasma Big ET-1 levels and their relation to hypertension and skin lesions in As exposed individuals in Bangladesh. A total of 304 study subjects from the As-endemic and non-endemic areas in Bangladesh were recruited for this study. As concentrations in water, hair and nails were measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). The plasma Big ET-1 levels were measured using a one-step sandwich enzyme immunoassay kit. Significant increase in Big ET-1 levels were observed with the increasing concentrations of As in drinking water, hair and nails. Further, before and after adjusting with different covariates, plasma Big ET-1 levels were found to be significantly associated with the water, hair and nail As concentrations of the study subjects. Big ET-1 levels were also higher in the higher exposure groups compared to the lowest (reference) group. Interestingly, we observed that Big ET-1 levels were significantly higher in the hypertensive and skin lesion groups compared to the normotensive and without skin lesion counterpart, respectively of the study subjects in As-endemic areas. Thus, this study demonstrated a novel dose–response relationship between As exposure and plasma Big ET-1 levels indicating the possible involvement of plasma Big ET-1 levels in As-induced hypertension and skin lesions. -- Highlights: ► Plasma Big ET-1 is an indicator of endothelial damage. ► Plasma Big ET-1 level increases dose-dependently in arsenic exposed individuals. ► Study subjects in arsenic-endemic areas with hypertension have elevated Big ET-1 levels. ► Study subjects with arsenic

  2. Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB2 in malaria exposed individuals

    Directory of Open Access Journals (Sweden)

    John Chandy C

    2009-10-01

    Full Text Available Abstract Background MB2 protein is a sporozoite surface antigen on the human malaria parasite Plasmodium falciparum. MB2 was identified by screening a P. falciparum sporozoite cDNA expression library using immune sera from a protected donor immunized via the bites of P. falciparum-infected irradiated mosquitoes. It is not known whether natural exposure to P. falciparum also induces the anti-MB2 response and if this response differs from that in protected individuals immunized via the bites of P. falciparum infected irradiated mosquitoes. The anti-MB2 antibody response may be part of a robust protective response against the sporozoite. Methods Fragments of polypeptide regions of MB2 were constructed as recombinant fusions sandwiched between glutathione S-transferase and a hexa histidine tag for bacterial expression. The hexa histidine tag affinity purified proteins were used to immunize rabbits and the polyclonal sera evaluated in an in vitro inhibition of sporozoite invasion assay. The proteins were also used in immunoblots with sera from a limited number of donors immunized via the bites of P. falciparum infected irradiated mosquitoes and plasma and serum obtained from naturally exposed individuals in Kenya. Results Rabbit polyclonal antibodies targeting the non-repeat region of the basic domain of MB2 inhibited sporozoites entry into HepG2-A16 cells in vitro. Analysis of serum from five human volunteers that were immunized via the bites of P. falciparum infected irradiated mosquitoes that developed immunity and were completely protected against subsequent challenge with non-irradiated parasite also had detectable levels of antibody against MB2 basic domain. In contrast, in three volunteers not protected, anti-MB2 antibodies were below the level of detection. Sera from protected volunteers preferentially recognized a non-repeat region of the basic domain of MB2, whereas plasma from naturally-infected individuals also had antibodies that

  3. Screening for methicillin-resistant Staphylococcus aureus carriers among individuals exposed and not exposed to the hospital environment and their antimicrobial sensitivity pattern

    Directory of Open Access Journals (Sweden)

    Bhadravathi Virupaksha Renushri

    2014-01-01

    Full Text Available Aims: This study evaluated the influence of exposure to the hospital environment on methicillin-resistant Staphylococcus aureus (MRSA carriage. The antibiograms of the MRSA isolates were examined. Materials and Methods: Nasal, throat, and web-space swabs were collected from 119 nursing students of the age group 18-23 years (exposed group and 100 age-matched pharmacy students (nonexposed group. S. aureus was identified and antibiogram obtained as per Clinical and Laboratory Standards Institute (CLSI guidelines. MRSA was detected by cefoxitin disc diffusion test and by growth on oxacillin screen agar as per CLSI guidelines. The presence of the mecA gene was confirmed by conventional polymerase chain reaction. Results: The MRSA carrier rates were 11.8% and 4% in the exposed and nonexposed groups, respectively. Association of exposure to the hospital environment with MRSA colonization was statistically significant. All MRSA isolates showed sensitivity to netilmicin, linezolid, tetracycline, vancomycin and teicoplanin. Among the exposed group, 71.4% MRSA isolates were resistant to ciprofloxacin, 64.3% to cotrimoxazole, 64.3% to erythromycin, 28.6% to gentamicin and 21.4% to clindamycin. Among the nonexposed group, 75% MRSA isolates were resistant to ciprofloxacin, 25% to cotrimoxazole, 25% to erythromycin, 25% to gentamicin and 25% to clindamycin. Conclusion: Exposure to the hospital environment was found to be a significant risk factor for MRSA carriage. Hospital-acquired MRSA (HA-MRSA isolates showed greater resistance toward antimicrobials compared with community-acquired MRSA (CA-MRSA isolates. This highlights the need for the appropriate institution of pharmacotherapy in cases of HA-MRSA and CA-MRSA infections and control of transmission by carriers.

  4. MUTATION SPECTRA OF SMOKY COAL COMBUSTION EMMISSIONS IN SALMONELLA REFLECTS THE TP53 AND KRAS MUTATIONS IN LUNG TUMORS FROM SMOKY COAL EXPOSED INDIVIDUALS

    Science.gov (United States)

    Mutation Spectra of Smoky Coal Combustion Emissions in Salmonella Reflect the TP53and KRAS Mutations in Lung Tumors from Smoky Coal-Exposed Individuals Abstract Nonsmoking women in Xuan Wei County, Yunnan Province, China who use smoky coal for cooking and h...

  5. Biological dose assessment by the analyses of chromosomal aberrations in 2 subjects accidentally exposed to ionizing radiation%2例电离辐射意外照射事件受检者染色体畸变分析和生物剂量估计

    Institute of Scientific and Technical Information of China (English)

    王金合; 姜峰; 韩林; 王平; 王喜爱; 吕玉民

    2011-01-01

    Objective: To investigate biological dose assessment by the analyses of chromosomal aberrations in 2 subjects accidentally exposed to ionizing radiation. Methods: Biological doses were estimated by the analysis of conventional chromosomal aberration from peripheral blood lymphocyte of the subjects. Results:The frequencies of dicentrics and translocation in 2 subjects were significantly higher than spontaneous frequency, and the equivalent whole body doses for the 2 subjects were estimated to be 0.21Gy (A) and 0.17Gy ( B) respectively. Conclusion:2 subjects suffered from over - exposure of ionizing radiation.%目的:对2例电离辐射意外照射事件受检人员进行外周血染色体畸变分析和生物剂量估计.方法:常规法分析受检者外周血淋巴细胞染色体畸变并估计受照剂量.结果:2例受检者的双着丝粒体和易位率均明显高于自发畸变率,估计的全身平均吸收剂量分别为0.21Gy(A)和0.17Gy(B).结论:2例受检者受到过量照射.

  6. Accidental hypothermia-an update

    DEFF Research Database (Denmark)

    Paal, Peter; Gordon, Les; Strapazzon, Giacomo

    2016-01-01

    BACKGROUND: This paper provides an up-to-date review of the management and outcome of accidental hypothermia patients with and without cardiac arrest. METHODS: The authors reviewed the relevant literature in their specialist field. Summaries were merged, discussed and approved to produce this nar...

  7. Accidente de Trabajo y Recargo

    OpenAIRE

    Pérez Alonso, María Antonia

    2015-01-01

    En la actualidad existen diferentes formas de Accidente de Trabajo. En el presente trabajo se da a conocer las distintas formas y la doctrina de los tribunales. Se aborda el recargo de prestaciones de Seguridad Social y el deber del empresario en cumplir la normativa de Seguridad Social

  8. Accidental blood exposures among medical residents in Paris, France.

    Science.gov (United States)

    Mir, O; Adam, J; Veyrie, N; Chousterman, B; Gaillard, R; Gregory, T; Yordanov, Y; Berveiller, P; Loulergue, P

    2011-03-01

    Accidental blood exposure (ABE) exposes healthcare workers, including medical residents, to the risk of occupational infection. We aimed to determine the characteristics of ABEs in residents with an anonymous self-reporting electronic questionnaire. A total of 350 residents (33% from surgical disciplines) entered this survey. One hundred and eighty-five residents (52%) reported at least one ABE during their residency (median, 2; range, 1-25), 53% of which occurred in operating theatres. Sixty-nine per cent of residents followed the current procedures for local disinfection. ABEs were notified to the hospital administration by 62% of residents, but only 51% of residents were referred to the occupational medicine department. The most frequently reported concerns following ABEs were human immunodeficiency virus (52%) and hepatitis C virus infection (39%). In 74% of cases, the serological status of the index patient was investigated. Only 54% of residents were aware of their hepatitis B surface antibody titres. Medical residents behaved inappropriately in 33% of cases in this survey. Further educational programmes should include residents, and not only senior healthcare workers, in order to improve individual behaviours.

  9. The radiological impact on the Greater London population of postulated accidental releases from the Sizewell PWR

    CERN Document Server

    Kelly, G N; Charles, D; Hemming, C R

    1983-01-01

    This report contains an assessment of the radiological impact on the Greater London population of postulated accidental releases from the Sizewell PWR. Three of the degraded core accident releases postulated by the CEGB are analysed. The consequences, conditional upon each release, are evaluated in terms of the health impact on the exposed population and the impact of countermeasures taken to limit the exposure. Consideration is given to the risk to the Greater London population as a whole and to individuals within it. The consequences are evaluated using the NRPB code MARC (Methodology for Assessing Radiological Consequences). The results presented in this report are all conditional upon the occurrence of each release. In assessing the significance of the results, due account must be taken of the frequency with which such releases may be predicted to occur.

  10. Potential load reductions on megawatt turbines exposed to wakes using individual-pitch wake compensator and trailing-edge flaps

    DEFF Research Database (Denmark)

    Markou, Helen; Andersen, Peter Bjørn; Larsen, Gunner Chr.

    2011-01-01

    that typically focus on either load or power prediction. As a consequence, the wake affected inflow field generated by the DWM formulation opens for control strategies for the individual turbine. Two different control approaches for load reduction on the individual turbines are implemented in the multi-body aero......, is extracted from measurements of the blade-root bending moment and/or one-point recordings of flow angle of attack to the blades (pitot tube) measurements. In the former implementation, the pitch angle of each blade is compensated for as an addition to the collective-pitch, rotor-speed control. In the latter...

  11. Cardiac autonomic reactivity and salivary cortisol in men and women exposed to social stressors : relationship with individual ethological profile

    NARCIS (Netherlands)

    Sgoifo, A; Braglia, F; Costoli, T; Musso, E; Meerlo, P; Ceresini, G; Troisi, A

    2003-01-01

    The degree of cardiovascular stress responsivity and its possible implications for the onset and progression of cardiovascular pathologies seem to be linked to the individual strategy of behavioral coping with stressors. This study was designed to investigate the relationship among cardiac autonomic

  12. Accidental haloperidol poisoning in children

    Directory of Open Access Journals (Sweden)

    Mona P Gajre

    2012-01-01

    Full Text Available Haloperidol, a butyrophenone neuroleptic drug, is an antipsychotic used in the treatment of adult schizophrenia and mania. It is used in children with neurological disorders like chorea and developmental disorders such as hyperactivity. With the advent of newer selective neuroleptics use of haloperidol is now on decline. However, in adults it is still the preferred drug especially in resource challenged settings. Extrapyramidal reactions occur frequently with haloperidol predominantly as parkinsonian symptoms. There are few case reports of accidental haloperidol poisoning in children and this one of them.

  13. LESSONS LEARNED FROM THE EURADOS SURVEY ON INDIVIDUAL MONITORING DATA AND INTERNAL DOSE ASSESSMENTS OF FOREIGNERS EXPOSED IN JAPAN FOLLOWING THE FUKUSHIMA DAIICHI NPP ACCIDENT.

    Science.gov (United States)

    Lopez, M A; Fojtik, P; Franck, D; Osko, J; Gerstmann, U; Scholl, C; Lebacq, A L; Breustedt, B; Del Risco Norrlid, L

    2016-09-01

    European Radiation Dosimetry Group e.V. (EURADOS) survey on individual monitoring data and dose assessment has been carried out for 550 foreigners returning home after being exposed in Japan to intakes of radionuclides (mainly (131)I, (132)I, (132)Te, (134)Cs and (137)Cs) as a consequence of the Fukushima Daiichi NPP accident. In vivo and in vitro measurements were performed in their respective countries at an early stage after that accident. Intakes of radionuclides were detected in 208 persons from Europe and Canada, but the committed effective dose E(50) was below the annual dose limit for the public (<1 mSv) in all the cases. Lessons learned from this EURADOS survey are presented here regarding not only internal dosimetry issues, but also the management of the emergency situation, the perception of the risk of health effects due to radiation and the communication with exposed persons who showed anxiety and lack of trust in monitoring data and dose assessments.

  14. Arterial pressure oscillations are not associated with muscle sympathetic nerve activity in individuals exposed to central hypovolaemia

    Science.gov (United States)

    2011-09-19

    of the blood pressure waveform in dogs (Guyton & Harris, 1951). Because these oscillations were attenuated by sino- aortic denervation, the authors...Task Force of the European Society of Cardiology , 1996); individually identified burst areas were used for MSNA oscillation determination. We...marker of sympatho-vagal interaction in man and conscious dog . Circ Res 59, 178–193. Pagani M, Montano N, Porta A, Malliani A, Abboud FM, Birkett C

  15. Linking Measures of Colony and Individual Honey Bee Health to Survival among Apiaries Exposed to Varying Agricultural Land Use

    Science.gov (United States)

    Smart, Matthew; Pettis, Jeff; Rice, Nathan; Browning, Zac; Spivak, Marla

    2016-01-01

    We previously characterized and quantified the influence of land use on survival and productivity of colonies positioned in six apiaries and found that colonies in apiaries surrounded by more land in uncultivated forage experienced greater annual survival, and generally more honey production. Here, detailed metrics of honey bee health were assessed over three years in colonies positioned in the same six apiaries. The colonies were located in North Dakota during the summer months and were transported to California for almond pollination every winter. Our aim was to identify relationships among measures of colony and individual bee health that impacted and predicted overwintering survival of colonies. We tested the hypothesis that colonies in apiaries surrounded by more favorable land use conditions would experience improved health. We modeled colony and individual bee health indices at a critical time point (autumn, prior to overwintering) and related them to eventual spring survival for California almond pollination. Colony measures that predicted overwintering apiary survival included the amount of pollen collected, brood production, and Varroa destructor mite levels. At the individual bee level, expression of vitellogenin, defensin1, and lysozyme2 were important markers of overwinter survival. This study is a novel first step toward identifying pertinent physiological responses in honey bees that result from their positioning near varying landscape features in intensive agricultural environments. PMID:27027871

  16. Linking Measures of Colony and Individual Honey Bee Health to Survival among Apiaries Exposed to Varying Agricultural Land Use.

    Directory of Open Access Journals (Sweden)

    Matthew Smart

    Full Text Available We previously characterized and quantified the influence of land use on survival and productivity of colonies positioned in six apiaries and found that colonies in apiaries surrounded by more land in uncultivated forage experienced greater annual survival, and generally more honey production. Here, detailed metrics of honey bee health were assessed over three years in colonies positioned in the same six apiaries. The colonies were located in North Dakota during the summer months and were transported to California for almond pollination every winter. Our aim was to identify relationships among measures of colony and individual bee health that impacted and predicted overwintering survival of colonies. We tested the hypothesis that colonies in apiaries surrounded by more favorable land use conditions would experience improved health. We modeled colony and individual bee health indices at a critical time point (autumn, prior to overwintering and related them to eventual spring survival for California almond pollination. Colony measures that predicted overwintering apiary survival included the amount of pollen collected, brood production, and Varroa destructor mite levels. At the individual bee level, expression of vitellogenin, defensin1, and lysozyme2 were important markers of overwinter survival. This study is a novel first step toward identifying pertinent physiological responses in honey bees that result from their positioning near varying landscape features in intensive agricultural environments.

  17. Quick management of accidental tritium exposure cases.

    Science.gov (United States)

    Singh, Vishwanath P; Badiger, N M; Managanvi, S S; Bhat, H R

    2012-07-01

    Removal half-life (RHL) of tritium is one of the best means for optimising medical treatment, reduction of committed effective dose (CED) and quick/easy handling of a large group of workers for medical treatment reference. The removal of tritium from the body depends on age, temperature, relative humidity and daily rainfall; so tritium removal rate, its follow-up and proper data analysis and recording are the best techniques for management of accidental acute tritium exposed cases. The decision of referring for medical treatment or medical intervention (MI) would be based on workers' tritium RHL history taken from their bodies at the facilities. The workers with tritium intake up to 1 ALI shall not be considered for medical treatment as it is a derived limit of annual total effective dose. The short-term MI may be considered for tritium intake of 1-10 ALI; however, if the results show intake ≥100 ALI, extended strong medical/therapeutic intervention may be recommended based on the severity of exposure for maximum CED reduction requirements and annual total effective dose limit. The methodology is very useful for pressurized heavy water reactors (PHWRs) which are mainly operated by Canada and India and future fusion reactor technologies. Proper management will optimise the cases for medical treatment and enhance public acceptance of nuclear fission and fusion reactor technologies.

  18. T cell clones from Schistosoma haematobium infected and exposed individuals lacking distinct cytokine profiles for Th1/Th2 polarisation

    Directory of Open Access Journals (Sweden)

    Mduluza T

    2001-01-01

    Full Text Available T cell clones were derived from peripheral blood mononuclear cells of Schistosoma haematobium infected and uninfected individuals living in an endemic area. The clones were stimulated with S. haematobium worm and egg antigens and purified protein derivative. Attempts were made to classify the T cell clones according to production of the cytokines IL-4, IL-5 and IFN-gamma. All the T cell clones derived were observed to produce cytokines used as markers for the classification of Th1/Th2 subsets. However, the 'signature' cytokines marking each subset were produced at different levels. The classification depended on the dominating cytokine type, which was having either Th0/1 or Th0/2 subsets. The results indicated that no distinct cytokine profiles for polarisation of Th1/Th2 subsets were detected in these S. haematobium infected humans. The balance in the profiles of cytokines marking each subset were related to infection and re-infection status after treatment with praziquantel. In the present study, as judged by the changes in infection status with time, the T cell responses appeared to be less stable and more dynamic, suggesting that small quantitative changes in the balance of the cytokines response could result in either susceptibility or resistant to S. haematobium infection.

  19. Detection of p53 and K-ras mutations in sputum of individuals exposed to smoky coal emissions in Xuan Wei County, China

    Energy Technology Data Exchange (ETDEWEB)

    Keohavong, P.; Lan, Q.; Gao, W.M.; Zheng, K.C.; Mady, H.H.; Melhem, M.F.; Mumford, J.L. [University of Pittsburgh, Pittsburgh, PA (US). Graduate School of Public Health

    2005-02-01

    Lung cancer mortality rates in the Xuan Wei County population are among the highest in China and are associated with exposure to indoor emissions from the burning of smoky coal. Previous studies of lung tumors from both non-smoking women and smoking men in this region showed high frequencies of mutations, consisting mostly of G {yields} T transversions in the p53 tumor suppressor gene and K-ras oncogene, suggesting that these mutations were caused primarily by polycyclic aromatic hydrocarbons. In this study sputum samples from 92 individuals with no evidence of lung cancer from Xuan Wei County were screened for p53 and K-ras mutations. Sputum cells were collected on glass slides by sputum cytocentrifugation, stained and cytopathologically analyzed. Cytologically non-malignant epithelial cells were taken from each sputum sample using a laser capture microdissection microscope and molecularly analyzed. Cells taken from the sputum of 15 (16.3%) individuals were mutation positive, including 13 (14.1%) individuals each with a p53 mutation, 1 (1.1%) individual with a K-ras mutation and 1 (1.1%) individual with a p53 and a K-ras mutation. p53 mutations were found in both the sputum of individuals with evidence of chronic bronchitis (3 of 46 or 6.5%) and those without evidence of this disease (11 of 46 or 23.9%). Therefore, mutations in the p53 gene and, to a lesser extent, the K-ras gene were frequent in non-malignant epithelial cells taken from the sputum of individuals without evidence of lung cancer who were exposed to smoky coal emissions in Xuan Wei County and were at a high risk for developing the disease.

  20. Individual repair for exposed testicles caused by necrotizing fasciitis%坏死性筋膜炎致睾丸外露的个体化修复

    Institute of Scientific and Technical Information of China (English)

    李红卫; 赵永健; 王亚菲; 梁彦辉; 赵全

    2014-01-01

    目的:探讨坏死性筋膜炎致睾丸外露的个体化修复方法。方法入选坏死性筋膜炎致睾丸外露患者15例,应用阴囊皮瓣修复6例,两步法阴囊再造3例,阴股沟皮瓣修复4例,股前外侧皮瓣修复2例。结果15例患者均达到满意修复。随访6~30个月,外观及功能良好。结论根据坏死性筋膜炎导致阴囊及会阴周围皮肤缺损情况,应选择个体化的手术方法来修复睾丸外露。%Objective To explore the individual repair method for exposed testicles caused by necrotizing fasciitis. Methods Total of 15 exposed testicles patients caused by necrotizing fasciitis were repaired by different methods. Six cases were repaired by scrotal skin flap, 3 cases were repaired by two-step scrotal reconstruction, 4 cases were repaired by pudendal thigh flap, 2 cases were repaired by anterolateral femoral flap. Results All patients were followed up for 6 ~30 months, all cases were satisfied with appearance and function. Conclusion According to the condition of scrotum and perineum skin defect, we should choose individual methods to repair exposed testicles.

  1. Accidental inflation in the landscape

    Energy Technology Data Exchange (ETDEWEB)

    Blanco-Pillado, Jose J.; Metallinos, Konstantinos [Institute of Cosmology, Department of Physics and Astronomy, Tufts University, Medford, MA (United States); Gomez-Reino, Marta, E-mail: jose@cosmos.phy.tufts.edu, E-mail: marta.gomez-reino.perez@cern.ch, E-mail: Konstantinos.Metallinos@tufts.edu [Department of Physics, University of Oviedo, Oviedo (Spain)

    2013-02-01

    We study some aspects of fine tuning in inflationary scenarios within string theory flux compactifications and, in particular, in models of accidental inflation. We investigate the possibility that the apparent fine-tuning of the low energy parameters of the theory needed to have inflation can be generically obtained by scanning the values of the fluxes over the landscape. Furthermore, we find that the existence of a landscape of eternal inflation in this model provides us with a natural theory of initial conditions for the inflationary period in our vacuum. We demonstrate how these two effects work in a small corner of the landscape associated with the complex structure of the Calabi-Yau manifold P{sup 4}{sub [1,1,1,6,9]} by numerically investigating the flux vacua of a reduced moduli space. This allows us to obtain the distribution of observable parameters for inflation in this mini-landscape directly from the fluxes.

  2. Accidental Inflation in the Landscape

    CERN Document Server

    Blanco-Pillado, Jose J; Metallinos, Konstantinos

    2012-01-01

    We study some aspects of fine tuning in inflationary scenarios within string theory flux compactifications and, in particular, in models of accidental inflation. We investigate the possibility that the apparent fine-tuning of the low energy parameters of the theory needed to have inflation can be generically obtained by scanning the values of the fluxes over the landscape. Furthermore, we find that the existence of a landscape of eternal inflation in this model provides us with a natural theory of initial conditions for the inflationary period in our vacuum. We demonstrate how these two effects work in a small corner of the landscape associated with the complex structure of the Calabi-Yau manifold P^4_[1,1,1,6,9] by numerically investigating the flux vacua of a reduced moduli space. This allows us to obtain the distribution of observable parameters for inflation in this mini-landscape directly from the fluxes.

  3. Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos

    Science.gov (United States)

    Wheelock, C.E.; Eder, K.J.; Werner, I.; Huang, H.; Jones, P.D.; Brammell, B.F.; Elskus, A.A.; Hammock, B.D.

    2005-01-01

    Acetylcholinesterase (AChE) activity has traditionally been monitored as a biomarker of organophosphate (OP) and/or carbamate exposure. However, AChE activity may not be the most sensitive endpoint for these agrochemicals, because OPs can cause adverse physiological effects at concentrations that do not affect AChE activity. Carboxylesterases are a related family of enzymes that have higher affinity than AChE for some OPs and carbamates and may be more sensitive indicators of environmental exposure to these pesticides. In this study, carboxylesterase and AChE activity, cytochrome P4501A (CYP1A) protein levels, and mortality were measured in individual juvenile Chinook salmon (Oncorhynchus tshawytscha) following exposure to an OP (chlorpyrifos) and a pyrethroid (esfenvalerate). As expected, high doses of chlorpyrifos and esfenvalerate were acutely toxic, with nominal concentrations (100 and 1 ??g/l, respectively) causing 100% mortality within 96 h. Exposure to chlorpyrifos at a high dose (7.3 ??g/l), but not a low dose (1.2 ??g/l), significantly inhibited AChE activity in both brain and muscle tissue (85% and 92% inhibition, respectively), while esfenvalerate exposure had no effect. In contrast, liver carboxylesterase activity was significantly inhibited at both the low and high chlorpyrifos dose exposure (56% and 79% inhibition, respectively), while esfenvalerate exposure still had little effect. The inhibition of carboxylesterase activity at levels of chlorpyrifos that did not affect AChE activity suggests that some salmon carboxylesterase isozymes may be more sensitive than AChE to inhibition by OPs. CYP1A protein levels were ???30% suppressed by chlorpyrifos exposure at the high dose, but esfenvalerate had no effect. Three teleost species, Chinook salmon, medaka (Oryzias latipes) and Sacramento splittail (Pogonichthys macrolepidotus), were examined for their ability to hydrolyze a series of pyrethroid surrogate substrates and in all cases hydrolysis activity was

  4. Instrumentation for the individual dosimetry of workers

    CERN Document Server

    Thévenin, J C

    2003-01-01

    The control of the radiation dose exposure of workers and personnel exposed to ionizing radiations (nuclear industry, nuclear medicine, army, university laboratories etc..) is ensured by individual dosemeters. This dosimetry is mandatory for all workers susceptible to be exposed to more than 30% of the regulatory dose limit. dosemeters are worn on the chest and in some particular cases, on the finger (dosemeter rings) or on the wrist. Passive dosemeters allow to measure the dose a posteriori, while electronic dosemeters allow a direct reading and recording of the dose. This article presents successively: 1 - the general principles of individual dosimetry: situations of exposure, radiation detection, operational data, standardization, calibration and quality assurance, measurement uncertainties; 2 - goals and regulatory framework of individual dosimetry: regulation and recommendations, optimization, respect of dose limits, accidental situations; 3 - passive dosemeters: film, thermoluminescent, radio-photolumin...

  5. Individuals Who Believe in the Paranormal Expose Themselves to Biased Information and Develop More Causal Illusions than Nonbelievers in the Laboratory.

    Directory of Open Access Journals (Sweden)

    Fernando Blanco

    Full Text Available In the reasoning literature, paranormal beliefs have been proposed to be linked to two related phenomena: a biased perception of causality and a biased information-sampling strategy (believers tend to test fewer hypotheses and prefer confirmatory information. In parallel, recent contingency learning studies showed that, when two unrelated events coincide frequently, individuals interpret this ambiguous pattern as evidence of a causal relationship. Moreover, the latter studies indicate that sampling more cause-present cases than cause-absent cases strengthens the illusion. If paranormal believers actually exhibit a biased exposure to the available information, they should also show this bias in the contingency learning task: they would in fact expose themselves to more cause-present cases than cause-absent trials. Thus, by combining the two traditions, we predicted that believers in the paranormal would be more vulnerable to developing causal illusions in the laboratory than nonbelievers because there is a bias in the information they experience. In this study, we found that paranormal beliefs (measured using a questionnaire correlated with causal illusions (assessed by using contingency judgments. As expected, this correlation was mediated entirely by the believers' tendency to expose themselves to more cause-present cases. The association between paranormal beliefs, biased exposure to information, and causal illusions was only observed for ambiguous materials (i.e., the noncontingent condition. In contrast, the participants' ability to detect causal relationships which did exist (i.e., the contingent condition was unaffected by their susceptibility to believe in paranormal phenomena.

  6. Individuals Who Believe in the Paranormal Expose Themselves to Biased Information and Develop More Causal Illusions than Nonbelievers in the Laboratory.

    Science.gov (United States)

    Blanco, Fernando; Barberia, Itxaso; Matute, Helena

    2015-01-01

    In the reasoning literature, paranormal beliefs have been proposed to be linked to two related phenomena: a biased perception of causality and a biased information-sampling strategy (believers tend to test fewer hypotheses and prefer confirmatory information). In parallel, recent contingency learning studies showed that, when two unrelated events coincide frequently, individuals interpret this ambiguous pattern as evidence of a causal relationship. Moreover, the latter studies indicate that sampling more cause-present cases than cause-absent cases strengthens the illusion. If paranormal believers actually exhibit a biased exposure to the available information, they should also show this bias in the contingency learning task: they would in fact expose themselves to more cause-present cases than cause-absent trials. Thus, by combining the two traditions, we predicted that believers in the paranormal would be more vulnerable to developing causal illusions in the laboratory than nonbelievers because there is a bias in the information they experience. In this study, we found that paranormal beliefs (measured using a questionnaire) correlated with causal illusions (assessed by using contingency judgments). As expected, this correlation was mediated entirely by the believers' tendency to expose themselves to more cause-present cases. The association between paranormal beliefs, biased exposure to information, and causal illusions was only observed for ambiguous materials (i.e., the noncontingent condition). In contrast, the participants' ability to detect causal relationships which did exist (i.e., the contingent condition) was unaffected by their susceptibility to believe in paranormal phenomena.

  7. Study of dose and relative risk of occupationally exposed individuals in interventional procedures; Estudo de dose e risco relativo de individuos ocupacionalmente expostos em procedimentos intervencionistas

    Energy Technology Data Exchange (ETDEWEB)

    Silveira Filho, Jose A.M.; Reis, Charlene O.; Taniguti, Lana T.; Pacifico, Leonardo C.; SaintYves, Thalis L.A.; Mecca, Fernando A., E-mail: ze_augustomsf@hotmail.com [Instituto Nacional do Cancer (INCA), Rio de Janeiro, RJ (Brazil). Setor de Fisica Medica

    2012-12-15

    This paper estimates the occupational effective dose and the relative risk of leukemia and cancers of the digestive tract mortality through dose study of the most radiosensitive anatomical regions (lens, thyroid, chest and gonads) of the professionals involved in interventional gonad procedures. It was considered a cumulative exposure time of 10,000 hours, which is the occupational exposure time of an IOE in throughout his professional life. It was also considered that they always use Personal Protective Equipment (PPE). Mathematical models derived from epidemiological data contained in the BEIR V and in the IAEA’s TECDOC 870 are used to estimate the relative risk. The results show a significant increase in mortality risk for these types of cancer for individuals occupationally exposed to three different distances from the x-ray beam, and reinforces that radiation protection measures are essential. (author)

  8. A prospective study of the potential moderating role of social support in preventing marginalization among individuals exposed to bullying and abuse in junior high school.

    Science.gov (United States)

    Strøm, Ida Frugård; Thoresen, Siri; Wentzel-Larsen, Tore; Sagatun, Åse; Dyb, Grete

    2014-10-01

    Negative physical and psychological long-term consequences of abuse and bullying are well documented. It is reasonable to assume that abuse and bullying early in life also may have an impact on the ability to work and stay economically independent later in life, but such prospective studies are lacking. This study investigates the consequences of exposure to abuse and bullying in junior high school, as measured by receiving long-term social welfare benefits in young adulthood. In addition, it explores the potential protective role of social support. Self-reported data from 13,633 (50.3% female) junior high school students were linked to registry data on their use of social welfare benefits from the age of 18 and for eight consecutive years. Cox regression analyses were applied to test the relationship between exposure to life adversities and the use of social welfare benefits, and the potential moderating role of social support. The analyses showed that individuals exposed to abuse and bullying had an increased likelihood of receiving social-welfare benefits compared with individuals not exposed to these types of abuse. Exposure to multiple types of abuse led to a higher likelihood of using social welfare benefits compared with single types of abuse and no abuse. The findings on the potential moderating role of social support were mixed, depending on the source of social support. Family support and classmate relationships were protective in reducing the likelihood of the use of social welfare benefits, whereas peer and teachers' support showed inconsistent patterns. These results are promising in terms of preventing the long-term negative consequences of abuse and bullying.

  9. Accidental methanol ingestion: Case report

    Directory of Open Access Journals (Sweden)

    Bakker Jan

    2010-02-01

    Full Text Available Abstract Background The incidence of methanol (CH3OH intoxication differs enormously from country to country. Methanol intoxication is extremely rare in the Dutch population. Even a low dose can already be potentially lethal. Patients are conventionally treated with hemodialysis. Therefore we'd like to present a report of a foreign sailor in Rotterdam who accidentally caused himself severe methanol intoxication, with a maximum measured concentration of 4.4 g/L. Case presentation The patient presented with hemodynamic instability and severe metabolic acidosis with pH 6.69. The anion gap was 39 mmol/L and the osmol gap 73 mosmol/kg. Treatment with ethanol and continuous venovenous hemodiafiltration (CVVH-DF was initiated. Despite the hemodynamic instability it is was possible to achieve rapid correction of pH and methanol concentration with CVVH-DF while maintaining a stable and therapeutic ethanol serum concentration. Despite hemodynamic and acid-base improvement, our patient developed massive cerebral edema leading to brain death. Permission for organ donation was unfortunately not ascertained. Conclusions We conclude that in a hemodynamic instable situation high methanol concentrations and methanol-induced derangements of homeostasis are safely and effectively treated with CVVH-DF and that severe cerebral edema is another possible cause of death rather than the classical bleeding in the putamen area.

  10. NSAIDs and the risk of accidental falls in the elderly: a systematic review.

    Science.gov (United States)

    Hegeman, Judith; van den Bemt, Bart J F; Duysens, Jacques; van Limbeek, Jacques

    2009-01-01

    Accidental falls, especially those occurring in the elderly, are a major health and research topic nowadays. Besides environmental hazards and the physiological changes associated with aging, medication use (e.g. benzodiazepines, vasodilators and antidepressants) and polypharmacy are significant risk factors for falling as well. Exposure to NSAIDs has been associated with accidental falls too, although information on this area is less consistent. Therefore, the main goal of this review is to provide an updated overview of all the evidence published on the risk of falling due to NSAID use thus far. A systematic literature search for material published between 1966 and March 2008 in PubMed, EMBASE, the Cochrane Database of Systematic Reviews, Exerpta Medica, Current Contents and Science Citation Index was combined with a check of the reference lists of all the retrieved articles. Validity and data extraction of the eligible articles was assessed by adapted criteria, based on checklists that were originally developed to assess case-control or cohort studies. From the 16 selected articles, two studies were rejected because of clustering of data and one article was excluded because it contained the same data as that in one of the included articles. None of the articles retrieved included a randomized controlled trial. The remaining 13 studies all showed some lack in completeness of their statistical methods, and much variation in reporting of effects. The overall mean age was high in the study populations, leaving the results to be poorly generalizable to a larger population and other age categories. Despite these imperfections, all studies showed an increased risk of falling due to NSAID use (four significant, nine non-significant), and a tendency towards an increased fall risk with NSAID exposure could be noted. The results shown in the present review suggest that an increased risk for accidental falls is probable when elderly individuals are exposed to NSAIDs. The

  11. Frequency of CCR5 Delta-32 Mutation in Human Immunodeficiency Virus (HIV-seropositive and HIV-exposed Seronegative Individuals and in General Population of Medellin, Colombia

    Directory of Open Access Journals (Sweden)

    Francisco J Díaz

    2000-04-01

    Full Text Available Repeated exposure to human immunodeficiency virus (HIV does not always result in seroconversion. Modifications in coreceptors for HIV entrance to target cells are one of the factors that block the infection. We studied the frequency of Delta-32 mutation in ccr5 gene in Medellin, Colombia. Two hundred and eighteen individuals distributed in three different groups were analyzed for Delta-32 mutation in ccr5 gene by polymerase chain reaction (PCR: 29 HIV seropositive (SP, 39 exposed seronegative (ESN and 150 individuals as a general population sample (GPS. The frequency of the Delta-32 mutant allele was 3.8% for ESN, 2.7% for GPS and 1.7% for SP. Only one homozygous mutant genotype (Delta-32/Delta-32 was found among the ESN (2.6%. The heterozygous genotype (ccr5/Delta-32 was found in eight GPS (5.3%, in one SP (3.4% and in one ESN (2.6%. The differences in the allelic and genotypic frequencies among the three groups were not statistically significant. A comparison between the expected and the observed genotypic frequencies showed that these frequencies were significantly different for the ESN group, which indirectly suggests a protective effect of the mutant genotype (Delta-32/Delta-32. Since this mutant genotype explained the resistance of infection in only one of our ESN persons, different mechanisms of protection must be playing a more important role in this population.

  12. Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambaréné, Gabon.

    Science.gov (United States)

    Mordmüller, Benjamin; Szywon, Katja; Greutelaers, Benedikt; Esen, Meral; Mewono, Ludovic; Treut, Carolin; Mürbeth, Raymund E; Chilengi, Roma; Noor, Ramadhani; Kilama, Wen L; Imoukhuede, Egeruan Babatunde; Imbault, Nathalie; Leroy, Odile; Theisen, Michael; Jepsen, Søren; Milligan, Paul; Fendel, Rolf; Kremsner, Peter G; Issifou, Saadou

    2010-09-24

    Malaria is still one of the major public health threats in sub-Saharan Africa. An effective vaccine could be a sustainable control measure that can be integrated into existing health infrastructures. The malaria vaccine candidate GMZ2 is a recombinant fusion protein of conserved parts of Plasmodium falciparum Glutamate Rich Protein and Merozoite Surface Protein 3 adjuvanted with aluminium hydroxide. GMZ2 is immunogenic and well tolerated in malaria-naive adults from Germany. To assess safety and immunogenicity in malaria-exposed individuals, 40 adults from Lambaréné, Gabon were randomly assigned to receive either 100 μg GMZ2 or a rabies control vaccine three times in monthly intervals. Both vaccines were well tolerated. One month after a full course of vaccination, GMZ2-vaccinated individuals had 1.4-fold (95% confidence interval: [1.1, 1.7]) higher baseline-corrected anti-GMZ2 antibody levels and more GMZ2-specific memory B-cells compared to the rabies group (p=0.039), despite a high prevalence of GMZ2-specific immune reactivity due to previous intense exposure to P. falciparum.

  13. Nodular goiter after occupational accidental exposure to radiation

    Energy Technology Data Exchange (ETDEWEB)

    Pisarev, M.A. [Radiobiology, National Atomic Energy Commission, Buenos Aires (Argentina); Human Biochemistry, Uninversity of Buenos Aires, School of Medicine, Buenos Aires (Argentina); Schnitman, M. [Center of Endocrinology and Metabolism, French Hospital C.Milstein, Buenos Aires (Argentina)

    2012-07-01

    In the present paper we present the consequences of an accidental occupational radiation exposure at a local hospital in Buenos Aires. Control at a local radiology service showed the lack of correct shielding in the X-ray equipment. The physicians and technicians (14 persons) exposed to radiation during 12 months were examined. The survey shows that: a) In 11 out of 14 radiation-exposed patients nodular goiter developed and an additional patient had diffuse goiter which means a goiter incidence of 85.7%; b) In 5 of the nodular goiter patients an increase in the size or the appearance of new nodules was observed along the follow-up period. No cancer was detected by FNA; c) Hypothyroidism was observed in 3/14 patients, and an additional patient had an abnormal TRH-TSH test, suggesting subclinical hypothyroidism; and d) Increased circulating antithyroid antibodies were found in one of the hypothyroid patients

  14. DNA damage and decreased DNA repair in peripheral blood mononuclear cells in individuals exposed to arsenic and lead in a mining site.

    Science.gov (United States)

    Jasso-Pineda, Yolanda; Díaz-Barriga, Fernando; Calderón, Jaqueline; Yáñez, Leticia; Carrizales, Leticia; Pérez-Maldonado, Iván N

    2012-05-01

    The aim of this study was to evaluate DNA damage and the capacity for DNA repair in children exposed to arsenic and lead. During 2006, we studied a total of 85 healthy children (aged 4-11 years) who were residents of Villa de la Paz (community A), Matehuala (community B), and Soledad de Graciano Sanchez (community C) in San Luis Potosi, Mexico. The quantification of arsenic in urine (AsU) and lead in blood (PbB) was performed by atomic absorption spectrophotometry. The alkaline comet assay was used to evaluate DNA damage and DNA repair. The highest levels of AsU and PbB in children were found in community A (44.5 μg/g creatinine for arsenic and 11.4 μg/dL for lead), followed by community B (16.8 μg/g creatinine for arsenic and 7.3 μg/dL for lead) and finally by children living in community C (12.8 μg/g creatinine for arsenic and 5.3 μg/dL for lead). When DNA damage was assessed, children living in community A had the highest DNA damage. Analysis of these same cells 1 h after a challenge with H(2)O(2) 10 μM showed a dramatic increase in DNA damage in the cells of children living in community B and community C, but not in the cells of children living in community A. Moreover, significantly higher levels of DNA damage were observed 3 h after the challenge ended (repair period) in cells from individuals living in community A. Our results show that children exposed to metals might be more susceptible to DNA alterations.

  15. Mortalidad intrahospitalaria por accidente cerebrovascular

    Directory of Open Access Journals (Sweden)

    Federico Rodríguez Lucci

    2013-08-01

    Full Text Available La mortalidad global por accidente cerebrovascular (ACV ha disminuido en las últimas tres décadas, probablemente debido a un mejor control de los factores de riesgo vascular. La mortalidad hospitalaria por ACV ha sido tradicionalmente estimada entre 6 y 14% en la mayoría de las series comunicadas. Sin embargo, los datos de ensayos clínicos recientes sugieren que esta cifra sería sustancialmente menor. Se revisaron datos de pacientes internados con diagnóstico de ACV del Banco de Datos de Stroke de FLENI y los registros institucionales de mortalidad entre los años 2000 y 2010. Los subtipos de ACV isquémicos se clasificaron según criterios TOAST y los ACV hemorrágicos en hematomas intrapanquimatosos, hemorragias subaracnoideas aneurismáticas, malformaciones arteriovenosas y otros hematomas intraparenquimatosos. Se analizaron 1514 pacientes, 1079 (71% con ACV isquémico (grandes vasos 39%, cardioembólicos 27%, lacunares 9%, etiología indeterminada 14%, otras etiologías 11% y 435 (29% con ACV hemorrágico (intraparenquimatosos 27%, hemorragia subaracnoidea 30%, malformaciones arteriovenosas 25% y otros hematomas espontáneos 18%. Se registraron 38 muertes intrahospitalarias (17 ACV isquémicos y 21 ACV hemorrágicos, representando una mortalidad global del 2.5% (1.7% en ACV isquémicos y 4.8% en ACV hemorrágicos. No se registraron muertes asociadas al uso de fibrinolíticos endovenosos. La mortalidad intrahospitalaria en pacientes con ACV isquémico y hemorrágico en nuestro centro fue baja. El manejo en un centro dedicado a las enfermedades neurológicas y el enfoque multidisciplinario por personal médico y no médico entrenado en el cuidado de la enfermedad cerebrovascular podrían explicar, al menos en parte, estos resultados.

  16. Determination of radionuclides produced by neutrons in heavily exposed workers of the JCO criticality accident in Tokai-mura for estimating an individual's neutron fluence.

    Science.gov (United States)

    Muramatsu, Y; Noda, Y; Yonehara, H; Ishigure, N; Yoshida, S; Yukawa, M; Tagami, K; Ban-Nai, T; Uchida, S; Hirama, T; Akashi, M; Nakamura, Y

    2001-09-01

    In the Tokai-mura criticality accident, three workers were heavily exposed. Biological materials, such as blood, urine, vomit and hair, were collected from the workers and analyzed for radioactivities, produced by the neutron irradiation. Activation products. such as 24Na, -K and 82Br, were found in these materials by gamma-ray spectrometry. The radionuclide of the highest activity observed in biological materials was 24Na, e.g. the concentrations of this nuclide in the blood samples from the three patients at the accident time were 169, 92 and 23 Bq/ml, respectively. The concentrations of stable sodium in the same samples were determined by ICP-AES to obtain specific activities of 24Na (concentration ratio between the produced 24Na and stable 23Na), which are essential for estimating the neutron fluences and radiation doses. The specific activities of 24Na obtained for the three patients through the blood analysis were 8.2 x 10(4),4.3 x 10(4) and 1.2 x 10(4) Bq24Na/g23Na. Based on these values, individual's neutron fluences were estimated to be 5.7 x 10(11), 3.0 x 10(-1) and 0.85 x 10(11) cm(-2), respectively.

  17. Dose assessment of an accidental exposure at the IPNS

    Energy Technology Data Exchange (ETDEWEB)

    Campos Torres, M.M.

    1995-02-01

    Seven different methods were used to estimate the dose rate to a female worker who was accidentally exposed in the neutron PHOENIX beamline at the IPNS. Theoretical and measured entrance dose ranged from 550 mrem/min to 2850 mrem/min. Theoretical estimates were based on a Monte Carlo simulation of a spectrum provided by IPNS (Crawford Spectrum). Dose measurements were made with TLDs on phantoms and with ionization chambers in a water phantom. Estimates of the whole body total effective dose equivalent (TEDE) rate ranged from 5.2 mrem/min to 840 mrem/min. Assumed and measured quality factors ranged from 2.6 to 11.8. Cytogenetic analyses of blood samples detected no positive exposure. The recommended TEDE rate was 158 mrem/min. The TEDE was 750 mrem.

  18. Dose assessment of an accidental exposure at IPNS

    Energy Technology Data Exchange (ETDEWEB)

    Torres, M.M.C.

    1996-05-01

    Seven different methods were used to estimate the dose rate to a female worker who was accidentally exposed in the neutron PHOENIX beamline at the IPNS. Theoretical and measured entrance dose rates ranged from 550 mrem/min to 2,850 mrem/min. Theoretical estimates were based on a Monte Carlo simulation of a spectrum provided by IPNS (Crawford Spectrum). Dose measurements were made with TLDs on phantoms and with ionization chambers in a water phantom. Estimates of the whole body total effective dose equivalent (TEDE) rate ranged from 5.2 mrem/min to 840 mrem/min. Assumed and measured quality factors ranged from 2.6 to 11.8. Cytogenic analyses of blood samples detected no positive exposure. The recommended TEDE rate was 158 mrem/min. The TEDE was 750 mrem.

  19. Accidental fire in the West Hall

    CERN Document Server

    1977-01-01

    On January 7 an accidental fire due to the failure of standard circuit-breakers, destroyed the coils of two spectrometer magnets and severely damaged the apparatus of two experiments. See also photos 7701582X, 7701581X, 7701580X. (Annual Report 1977, pg. 127-128)

  20. High Expression of Antiviral and Vitamin D Pathway Genes Are a Natural Characteristic of a Small Cohort of HIV-1-Exposed Seronegative Individuals

    Science.gov (United States)

    Aguilar-Jimenez, Wbeimar; Saulle, Irma; Trabattoni, Daria; Vichi, Francesca; Lo Caputo, Sergio; Mazzotta, Francesco; Rugeles, Maria T.; Clerici, Mario; Biasin, Mara

    2017-01-01

    Natural resistance to HIV-1 infection is influenced by genetics, viral-exposure, and endogenous immunomodulators such as vitamin D (VitD), being a multifactorial phenomenon that characterizes HIV-1-exposed seronegative individuals (HESNs). We compared mRNA expression of 10 antivirals, 5 immunoregulators, and 3 VitD pathway genes by qRT-PCR in cells of a small cohort of 11 HESNs, 16 healthy-controls (HCs), and 11 seropositives (SPs) at baseline, in response to calcidiol (VitD precursor) and/or aldithriol-2-(AT2)-inactivated HIV-1. In addition, the expression of TIM-3 on T and NK cells of six HCs after calcidiol and calcitriol (active VitD) treatments was evaluated by flow cytometry. Calcidiol increased the mRNA expression of HAVCR2 (TIM-3; Th1-cells inhibitor) in HCs and HESNs. AT2-HIV-1 increased the mRNA expression of the activating VitD enzyme CYP27B1, of the endogenous antiviral proteins MX2, TRIM22, APOBEC3G, and of immunoregulators ERAP2 and HAVCR2, but reduced the mRNA expression of VitD receptor (VDR) and antiviral peptides PI3 and CAMP in all groups. Remarkably, higher mRNA levels of VDR, CYP27B1, PI3, CAMP, SLPI, and of ERAP2 were found in HESNs compared to HCs either at baseline or after stimuli. Furthermore, calcitriol increases the percentage of CD4+ T cells expressing TIM-3 protein compared to EtOH controls. These results suggest that high mRNA expression of antiviral and VitD pathway genes could be genetically determined in HESNs more than viral-induced at least in peripheral blood mononuclear cells. Moreover, the virus could potentiate bio-activation and use of VitD, maintaining the homeostasis of the immune system. Interestingly, VitD-induced TIM-3 on T cells, a T cell inhibitory and anti-HIV-1 molecule, requires further studies to analyze the functional outcomes during HIV-1 infection. PMID:28243241

  1. Causes of accidental childhood deaths in China in 2010: A systematic review and analysis

    Directory of Open Access Journals (Sweden)

    Kit Yee Chan

    2015-06-01

    Full Text Available Background Infectious causes of childhood deaths in the world have decreased substantially in the 21st century. This trend has exposed accidental deaths as an increasingly important future challenge. Presently, little is known about the cause structure of accidental childhood deaths in low– and middle–income country (LMIC settings In this paper, we aim to establish cause structure for accidental deaths in children aged 0–4 years in China in the year 2010. Methods In this paper, we explored the database of 208 multi–cause child mortality studies in Chinese that formed a basis for the first published estimate of the causes of child deaths in China (for the year 2008. Only five of those studies identified specific causes of accidental deaths. Because of this, we searched the Chinese medical literature databases CNKI and WanFang for single–cause mortality studies that were focused on accidental deaths. We identified 71 further studies that provided specific causes for accidental deaths. We used epidemiological modeling to estimate the number of accidental child deaths in China in 2010 and to assign those deaths to specific causes. Results In 2010, we estimated 314 581 deaths in children 0–4 years in China, of which 31 633 (10.1% were accidental. Accidental deaths contributed 7240 (4.0% of all deaths in neonatal period, 8838 (10.5% among all post–neonatal infant deaths, and 15 554 (31.7% among children with 1–4 years of age. Among four tested models, the most predictive was used to establish the likely cause structure of accidental deaths in China. We estimated that asphyxia caused 9490 (95% confidence interval (CI 8224–11 072, drowning 5694 (95% CI 5061–6327, traffic accidents 3796 (95% CI3163–4745, poisoning 3163 (95% CI 2531–3796 and falls 2531 (95% CI 2214–3163 deaths. Based on medians from a few rare studies, we also predict 633 (95% CI 316–1265 deaths to be due to burns and 316 (95% CI 0–633 due to falling objects

  2. [Accidental falls in the elderly].

    Science.gov (United States)

    Heinimann, Niklas B; Kressig, Reto W

    2014-06-18

    Falls in the elderly are common with consecutive high mortality and morbidity. Recent consecutive data focus on identification and therapy of intrinsic risk factors. Sarcopenia, imbalance and gait disorders represent the major risk factors. Sarcopenia is caused by a disequilibrium of protein synthesis and breakdown, probably in consequence of age-related changes in protein metabolism. Protein supplements in combination with strength training shows the best benefit. Disorders in balance and gait are caused by age-related or pathologic changes in a complex regulation system of gait. The individual fall risk correlates with the gait variability and even increases with bad dual task performance. Activities with high requirements of attention and body awareness are the most effective prevention for falls in the elderly (-50%).

  3. 5 CFR 870.206 - Accidental death and dismemberment.

    Science.gov (United States)

    2010-01-01

    ... REGULATIONS (CONTINUED) FEDERAL EMPLOYEES' GROUP LIFE INSURANCE PROGRAM Types and Amount of Insurance § 870..., accidental death benefits are equal to the amount of Option A. (c)(1) Under Basic insurance, accidental... automatic part of Basic and Option A insurance for employees. (2) There is no accidental death...

  4. Accidental ingestion of Ecstasy in a toddler.

    Science.gov (United States)

    Chang, Yi-Jung; Lai, Ming-Wei; Kong, Man-Shan; Chao, Hsun-Chin

    2005-12-01

    Toddlers who ingest the drug of abuse 3,4-methylenedioxymethamphetamine (MDMA; 'Ecstasy') are at particularly high risk of serious neurological and cardiovascular side effects. We report of a 20-month-old male toddler who accidentally ingested Ecstasy. He presented with fever and seizures, tachycardia, hypertension, and hyperthermia. Urine amphetamine level was 2111 ng/mL. Treatment included rapid cooling, hydration, and support measures. Vital signs were regularly monitored. His condition became stable on day 2 and urine amphetamine level returned to normal on day 3 of hospitalization. His behavior, activity, and appetite had returned to their usual levels upon follow-up at our outpatient clinic. The incidence of drug abuse with MDMA has increased dramatically over the last decade in developed countries. It can be expected that accidental Ecstasy poisoning in children will increase as well. This case illustrates the need to consider the possibility of accidental Ecstasy ingestion in the differential diagnosis of a child suffering from convulsions with fever.

  5. Influence of Some Detoxification Enzyme Polymorphisms on Cytogenetic Biomarkers Between Individuals Exposed to Very Low Doses of 1,3-Butadiene

    NARCIS (Netherlands)

    Bukvic, Nenad; Lovreglio, Piero; Fanelli, Margherita; Susca, Francesco C.; Ballini, Andrea; Lastella, Patrizia; Foa, Vito; Fustinoni, Silvia; Soleo, Leonardo; Guanti, Ginevra

    2009-01-01

    Objective: To evaluate the variation of some biomarkers related to the level of enzymatic activity dependent on the different polymorphisms. Methods: We studied 27 butadiene-exposed workers and 37 controls using different biomarkers of the genotoxic effect. The genotypes were determined using polyme

  6. Psychosocial interventions for children exposed to traumatic events in low- and middle-income countries: study protocol of an individual patient data meta-analysis

    NARCIS (Netherlands)

    Purgato, M.; Gross, A.L.; Jordans, M.J.D.; de Jong, J.T.V.M.; Barbui, C.; Tol, W.

    2014-01-01

    Background: The burden of mental health and psychosocial problems in children exposed to traumatic events in humanitarian settings in low- and middle-income countries is substantial. An increasing number of randomized studies has shown promising effects of psychosocial interventions, but this eviden

  7. The effects of exposure to different clastogens on the pattern of chromosomal aberrations detected by FISH whole chromosome painting in occupationally exposed individuals

    Energy Technology Data Exchange (ETDEWEB)

    Beskid, O. [Institute of Experimental Medicine AS CR and Health Institute of Central Bohemia, Videnska 1083, 142 20 Prague 4 (Czech Republic); Dusek, Z. [Institute of Experimental Medicine AS CR and Health Institute of Central Bohemia, Videnska 1083, 142 20 Prague 4 (Czech Republic); Solansky, I. [Institute of Experimental Medicine AS CR and Health Institute of Central Bohemia, Videnska 1083, 142 20 Prague 4 (Czech Republic); Sram, R.J. [Institute of Experimental Medicine AS CR and Health Institute of Central Bohemia, Videnska 1083, 142 20 Prague 4 (Czech Republic)]. E-mail: sram@biomed.cas.cz

    2006-02-22

    The pattern of chromosomal aberrations (CA) was studied by fluorescence in situ hybridization (FISH) technique (whole chromosomes 1 and 4 painting) in workers occupationally exposed to any of the four following conditions: acrylonitrile (ACN), ethyl benzene (EB), carcinogenic polycyclic aromatic hydrocarbons (c-PAHs), and irradiation in nuclear power plants (NPP), respectively. Decrease in the relative frequency of translocations was observed in EB group, and an increase in reciprocal translocations in ACN and NPP-exposed groups. An increase in a relative number of insertions was registered under all four conditions (significant at ACN, EB, c-PAHs, quasisignificant at NPP-exposed groups). Significant differences in the percentage of lymphocytes with aberrations on chromosome 1 (58.8 {+-} 32.7%, versus 73.8 {+-} 33.6% in the controls, P < 0.05), and chromosome 4 (47.0 {+-} 34.1%, versus 29.4 {+-} 32.2%, P < 0.01) were found in workers exposed to ACN. Similarly, a decrease in the proportion of cells with aberration on chromosome 1 (61.0 {+-} 24.0%, versus 73.8 {+-} 33.6%, P < 0.05) and an increase on chromosome 4 (45.6 {+-} 24.6%, versus 29.4 {+-} 32.2%, P < 0.05) were observed in workers exposed to EB. Frequency of aberrant cells (%AB.C.) as well as genomic frequency of translocations (F {sub G}/100) increased with age (P < 0.001). Aging also increased the percentage of translocations and reciprocal translocations (P < 0.05), but decreased the relative number of acentric fragments (P < 0.01). Smoking led to significantly increased F {sub G}/100 (P < 0.05), but did not affect the pattern of chromosomal aberrations. Our results seem to indicate that different carcinogens may induce a different pattern of chromosomal aberrations.

  8. Genetic Damage Induced by Accidental Environmental Pollutants

    Directory of Open Access Journals (Sweden)

    Beatriz Pérez-Cadahía

    2006-01-01

    Full Text Available Petroleum is one of the main energy sources worldwide. Its transport is performed by big tankers following some established marine routes. In the last 50 years a total amount of 37 oil tankers have given rise to great spills in different parts of the world, Prestige being the last one. After the accident, a big human mobilisation took place in order to clean beaches, rocks and fauna, trying to reduce the environmental consequences of this serious catastrophe. These people were exposed to the complex mixture of compounds contained in the oil. This study aimed at determine the level of environmental exposure to volatile organic compounds (VOC, and the possible damage induced on the population involved in the different cleaning tasks by applying the genotoxicity tests sister chromatid exchanges (SCE, micronucleus (MN test, and comet assay. Four groups of individuals were included: volunteers (V, hired manual workers (MW, hired high-pressure cleaner workers (HPW and controls. The higher VOC levels were associated with V environment, followed by MW and lastly by HPW, probably due to the use of high-pressure cleaners. Oil exposure during the cleaning tasks has caused an increase in the genotoxic damage in individuals, the comet assay being the most sensitive biomarker to detect it. Sex, age and tobacco consumption have shown to influence the level of genetic damage, while the effect of using protective devices was less noticeable than expected, perhaps because the kind used was not the most adequate.

  9. Accidental K\\"ahler Moduli Inflation

    CERN Document Server

    Maharana, Anshuman; Sumitomo, Yoske

    2015-01-01

    We study a model of accidental inflation in type IIB string theory where inflation occurs near the inflection point of a small K\\"ahler modulus. A racetrack structure helps to alleviate the known concern that string-loop corrections may spoil K\\"ahler Moduli Inflation unless having a significant suppression via the string coupling or a special brane setup. Also, the hierarchy of gauge group ranks required for the separation between moduli stabilization and inflationary dynamics is relaxed. The relaxation becomes more significant when we use the recently proposed D-term generated racetrack model.

  10. Accidental Kähler moduli inflation

    Energy Technology Data Exchange (ETDEWEB)

    Maharana, Anshuman [Harish Chandra Research Institute,Chhatnag Road, Jhunsi, Allahabad, UP 211019 (India); Rummel, Markus [Rudolph Peierls Centre for Theoretical Physics, University of Oxford,1 Keble Road, Oxford, OX1 3NP (United Kingdom); Sumitomo, Yoske [High Energy Accelerator Research Organization, KEK,1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan)

    2015-09-14

    We study a model of accidental inflation in type IIB string theory where inflation occurs near the inflection point of a small Kähler modulus. A racetrack structure helps to alleviate the known concern that string-loop corrections may spoil Kähler Moduli Inflation unless having a significant suppression via the string coupling or a special brane setup. Also, the hierarchy of gauge group ranks required for the separation between moduli stabilization and inflationary dynamics is relaxed. The relaxation becomes more significant when we use the recently proposed D-term generated racetrack model.

  11. Anaphylaxis after accidental ingestion of kiwi fruit.

    Science.gov (United States)

    Gawrońska-Ukleja, Ewa; Różalska, Anna; Ukleja-Sokołowska, Natalia; Zbikowska-Gotz, Magdalena; Bartuzi, Zbigniew

    2013-06-01

    Numerous cases of anaphylaxis after ingestion of kiwi fruit, after the skin tests and during oral immunotherapy were described. The article describes the case of severe anaphylactic reaction that occurred in a 55-year-old patient after accidental ingestion of kiwi. Allergy to kiwi fruit was confirmed by a native test with fresh kiwi fruit. After the test, the patient experienced generalized organ response in the form of headache, general weakness and rashes on the neck and breast, and dyspnea. The patient had significantly elevated levels of total IgE and IgE specific to kiwi fruit.

  12. Tratamiento del virus de hepatitis B en el accidente laboral

    Directory of Open Access Journals (Sweden)

    Henry Zamora-Barquero

    2008-11-01

    Full Text Available La exposición accidental al virus B entraña alto riesgo de contagio de la enfermedad. Su manejo incluye: medidas preventivas en el manejo de los pacientes, vacunar y confirmar inmunidad de los trabajadores, uso de inmunoglobulinas y vacunación posterior al accidente y disponer de protocolos de reporte precoz y clínicas en el manejo de los accidentes.

  13. Outcome of accidental hypothermia with or without circulatory arrest

    DEFF Research Database (Denmark)

    Wanscher, Michael; Agersnap, Lisbeth; Ravn, Jesper;

    2012-01-01

    Resuscitation guidelines for the treatment of accidental hypothermia are based primarily on isolated cases. Mortality rates are high despite aggressive treatment aimed at restoring spontaneous circulation and normothermia....

  14. El accidente de trabajo "in itinere": concepto legal y jurisprudencial

    OpenAIRE

    López Mejías, Ana

    2016-01-01

    El trabajo que voy a llevar a cabo trata sobre el accidente de trabajo, más en concreto el accidente de trabajo "in itinere", ya que es un hecho protegido que la ley general de la seguridad social le da una gran importancia. Trataré los requisitos necesarios para que se dé un accidente de trabajo "in itinere", basándome siempre en sentencias ya que es un trabajo básicamente jurisprudencial. En el trabajo también trato el accidente de trabajo in mision. A modo de conclusión expresaré mi opinió...

  15. Accidentes de tránsito terrestre

    Directory of Open Access Journals (Sweden)

    José Enrique Ramírez Muñoz

    2013-09-01

    Full Text Available Los accidentes de tránsito terrestres en Costa Rica se han convertido en un serio problema de salud pública, que derivan ya sea en lesiones graves o bien en muertes de personas de todas las edades. Estos eventos incluyen el atropellamiento, las colisiones y choques, y producen cuadros lesionológicos muy diversos de acuerdo a la participación de las personas, el tipo de vehículo y la forma en la que se produce el traumatismo. Así mismo, se debe tener en cuenta la participación de factores coadyuvantes como el uso del casco y el cinturón de seguridad, o bien el consumo de alcohol y el uso del teléfono móvil. La valoración médico legal de las víctimas, vivas o muertas de accidentes de tránsito, está a cargo del Departamento de Medicina Legal del Organismo de Investigación Judicial, y se hace por solicitud de una Autoridad Judicial competente.

  16. Alternative effector-function profiling identifies broad HIV-specific T-cell responses in highly HIV-exposed individuals who remain uninfected.

    Science.gov (United States)

    Ruiz-Riol, Marta; Llano, Anuska; Ibarrondo, Javier; Zamarreño, Jennifer; Yusim, Karina; Bach, Vanessa; Mothe, Beatriz; Perez-Alvarez, Susana; Fernandez, Marco A; Requena, Gerard; Meulbroek, Michael; Pujol, Ferran; Leon, Agathe; Cobarsi, Patricia; Korber, Bette T; Clotet, Bonaventura; Ganoza, Carmela; Sanchez, Jorge; Coll, Josep; Brander, Christian

    2015-03-15

    The characterization of host immune responses to human immunodeficiency virus (HIV) in HIV controllers and individuals with high exposure but seronegativity to HIV (HESN) is needed to guide the development of effective preventive and therapeutic vaccine candidates. However, several technical hurdles severely limit the definition of an effective virus-specific T-cell response. By using a toggle-peptide approach, which takes HIV sequence diversity into account, and a novel, boosted cytokine staining/flow cytometry strategy, we here describe new patterns of T-cell responses to HIV that would be missed by standard assays. Importantly, this approach also allows detection of broad and strong virus-specific T-cell responses in HESN individuals that are characterized by a T-helper type 1 cytokine-like effector profile and produce cytokines that have been associated with potential control of HIV infection, including interleukin 10, interleukin 13, and interleukin 22. These results establish a novel approach to improve the current understanding of HIV-specific T-cell immunity and identify cellular immune responses and individual cytokines as potential markers of relative HIV resistance. As such, the findings also help develop similar strategies for more-comprehensive assessments of host immune responses to other human infections and immune-mediated disorders.

  17. Avaliação da aptidão cardiopulmonar em indivíduos com hemiparesia após acidente vascular encefálico Evaluación de la aptitud cardiopulmonar en individuos con hemiparesia tras accidente vascular encefálico Evaluation of cardiopulmonary fitness in individuals with hemiparesis after cerebrovascular accident

    Directory of Open Access Journals (Sweden)

    Angélica Cristiane Ovando

    2011-02-01

    Full Text Available FUNDAMENTO: Devido à hemiparesia, a avaliação da aptidão cardiorrespiratória de indivíduos após acidente vascular encefálico (AVE, por meio de testes ergométricos com protocolos convencionais, tem se tornado um desafio. OBJETIVO: Realizar teste cardiopulmonar (TCP em hemiparéticos para uma avaliação pré-participação visando uma criteriosa prescrição de exercício aeróbico. MÉTODOS: Participaram do estudo 8 indivíduos com hemiparesia crônica, que foram submetidos a TCP realizado com protocolo individualizado em rampa, desenvolvido a partir da informação da velocidade de marcha dos indivíduos previamente avaliados em teste de pista. Foi considerada a proposta de inclinação variando entre 0 e 10,0%, velocidade inicial correspondente a 70,0% do ritmo de caminhada confortável e velocidade máxima 40,0% superior à velocidade máxima no teste de pista, na expectativa de que o TCP, com este incremento gradativo e constante da intensidade, durasse entre 6 e 8 minutos. RESULTADOS: Em 100,0% dos avaliados, o motivo para a interrupção do teste foi fadiga periférica. O VO2 de pico alcançado foi de 20,6 ± 5,7 ml/kg.min. O Limiar I foi identificado em todos os exames, situando-se em 82,64 ± 4,78% da FC de pico e 73,31 ± 4,97% do VO2 de pico. O quociente respiratório (R do grupo foi de 0,96 ± 0,09, e três dos 8 indivíduos (37,5% atingiram R superior a 1,00, sendo o Limiar II identificado nestes sujeitos. Foram encontradas relações positivas entre variáveis do TCP e escores de equilíbrio, desempenho no teste de caminhada de 6 minutos e velocidade de marcha no solo. CONCLUSÃO: O teste mostrou ser útil para prescrição de atividade física nesses indivíduos.FUNDAMENTO: Debido a la hemiparesia, la evaluación de la aptitud cardiorrespiratoria de individuos después de accidente vascular encefálico (AVE, por medio de pruebas ergométricas con protocolos convencionales, se ha vuelto en un reto. OBJETIVO: Llevar a cabo

  18. 21 CFR 1002.20 - Reporting of accidental radiation occurrences.

    Science.gov (United States)

    2010-04-01

    ... Occurrences § 1002.20 Reporting of accidental radiation occurrences. (a) Manufacturers of electronic products... the Director, Center for Devices and Radiological Health, all accidental radiation occurrences... radiation occurrence occurred; (3) The manufacturer, type, and model number of the electronic product...

  19. Course Management Systems for Learning: Beyond Accidental Pedagogy

    Science.gov (United States)

    McGee, Patricia; Carmean, Colleen; Jafari, Ali

    2005-01-01

    "Course Management Systems for Learning: Beyond Accidental Pedagogy" is a comprehensive overview of standards, practices and possibilities of course management systems in higher education. "Course Management Systems for Learning: Beyond Accidental Pedagogy" focuses on what the current knowledge is (in best practices, research, standards and…

  20. Tension pneumothorax following an accidental kerosene poisoning: A case report

    Directory of Open Access Journals (Sweden)

    G M Ashir

    2009-01-01

    Full Text Available Tension pneumothorax is a rare complication following an accidental kerosene poisoning. In such situation, a bed-side needle thoracocentesis is performed because of its potential of becoming fatal; hence its clinical importance. A case of 15 month old boy with tension pneumothorax following accidental kerosene poisioning that responded to needle thoracocentesis is presented.

  1. Tension pneumothorax following an accidental kerosene poisoning: A case report

    OpenAIRE

    2009-01-01

    Tension pneumothorax is a rare complication following an accidental kerosene poisoning. In such situation, a bed-side needle thoracocentesis is performed because of its potential of becoming fatal; hence its clinical importance. A case of 15 month old boy with tension pneumothorax following accidental kerosene poisioning that responded to needle thoracocentesis is presented.

  2. Exposing diversity

    DEFF Research Database (Denmark)

    Nørtoft, Kamilla; Nordentoft, Helle Merete

    . A prominent research theme in health care studies is, therefore, to explicate the gap between theory and practice. The question this paper addresses is how a learning environment can be designed to bridge this theory-practice gap, expose the differences in situated interactions and qualify health...... in the homes of older people and in pedagogical institutions targeting older people. In the paper we look at the potentials and challenges in working with ethnographic video narratives as a pedagogical tool. Our findings indicate that the use of video narratives has the potential to expose the diversity...

  3. Preventing and controlling accidental gas releases

    Science.gov (United States)

    Moskowitz, P. D.; Fthenakis, V. M.; Kalb, P. D.

    1988-07-01

    Toxic, flammable, and explosive gases may be used in photovoltaic cell research laboratories and in commercial manufacturing facilities. Accidental release of these materials can present hazards to life and property. Accidents can arise from a variety of mechanical and human related failures. These can occur from the time materials are received at the loading dock of the facility to the time treated gases are discharged to the atmosphere through a stack. Each type of initiating event may require a different control approach. These may range from the training and certification of plant workers charged with the handling of gas cylinder hookups to installation of emergency pollution control systems. Since engineering options for controlling released materials are limited, emphasis should be placed on administrative and engineering approaches for preventing such accidents. These are likely to be the most effective approaches for protecting life and property.

  4. Research progress in study of accidental hypothermia

    Directory of Open Access Journals (Sweden)

    Rui YUAN

    2016-04-01

    Full Text Available Accidental hypothermia refers to a state of lowering of core body temperature down to 35 ℃induced by drowning, burial in snow and prolonged exposure to cold environment, etc. Hypothermia may affect the cardiovascular system, respiratory system, digestive system, etc. The triad consisting "hypothermia, acidosis and coagulopathy" is an important factor accelerating the death of patients. Early, timely application of rewarming measures is regarded as the basic principle in treatment of hypothermia. A series of rewarming measures, such as infusion of warm fluids, inspiration of warm air, abdominal infusion of warm fluid, instruction of warm fluid into pleural cavity, intravenous infusion of warm fluid, rewarming through ECMO, etc. have been used recently. Advance in research on the classification of hypothermia, its impact to the body and the treatment methods are reviewed in present paper. DOI: 10.11855/j.issn.0577-7402.2016.04.15

  5. Accidental Contamination with Oil during Endodontic Surgery

    Science.gov (United States)

    Plascencia, Hugo; Díaz, Mariana; Cholico, Patricia; del Real, Monserrat; Márquez-de Alba, Salvador

    2016-01-01

    The modern surgical endodontic treatment is a safe and predictable procedure with high success rate. However, several factors can retard or impede the proper healing process. Use of a high speed handpiece during hard tissues management (osteotomy and apical resection) can potentially be one of these factors. Formation of metallic debris from the surgical diamond burs, production of necrotic local tissue due to overheating and the direct liberation of air from conventional handpiece into the working area are potential irritants able to delay the tissue healing. The aim of the present article is to report the histopathological findings of the trans-operational accidental contamination with oil in the surgical area during an endodontic surgery. PMID:27790269

  6. Accidental injuries in agriculture in the UK.

    Science.gov (United States)

    Solomon, C

    2002-12-01

    The rate of occupational accidents in British agriculture is higher than in most other industries. The most common fatal accidents are those involving vehicles and machinery, falls from a height and electrocution. A substantial proportion of reported non-fatal injuries in agricultural employees is attributable to manual handling, but among self-employed farmers the contribution is much smaller. Few data are available on longer-term determinants of risk, but accidental deaths are most frequent in July, August and September. The main approaches to preventing agricultural accidents are through engineering improvements, and education and training of the workforce. The introduction of roll-over protection structures for tractors has been an important development in recent decades. Other engineering controls include guards for power take off shafts, guard rails to prevent falls, better handling facilities for animals and closed transfer systems for pesticides. Training on safety is available from several sources, but its effectiveness in reducing accidents is uncertain.

  7. Rickettsial infection caused by accidental conjunctival inoculation

    Science.gov (United States)

    Brissos, Joao; de Sousa, Rita; Santos, Ana Sofia; Gouveia, Catarina

    2015-01-01

    The most common transmission route of tick-borne Rickettsia is through tick bite; nevertheless, other transmission routes should also be considered. We report a case of rickettsial infection in a 15-year-old boy caused by accidental contamination of the conjunctiva through the infected fluid of a crushed engorged tick removed from a dog. Right eye pain, conjunctival hyperaemia with mucopurulent exudate, chemosis and eyelid oedema were the first signs and symptoms. Two days later, the boy developed fever, myalgia, headache, abdominal pain and was vomiting; physical examination showed multiple cervical adenopathies but no rash. He was treated with doxycycline (200 mg/day) for 7 days with progressive resolution of clinical signs. Rickettsial infection was confirmed by immunofluorescence assay with serological seroconversion in two consecutive samples. Rickettsia conorii or Rickettsia massiliae were the possible causal agents since they are the Rickettsia spp found in the Rhipicephalus sanguineus dog tick in Portugal. PMID:25568272

  8. Antigen-driven C–C Chemokine-mediated HIV-1 Suppression by CD4+ T Cells from Exposed Uninfected Individuals Expressing the Wild-type CCR-5 Allele

    OpenAIRE

    1997-01-01

    Despite repeated exposure to HIV-1, certain individuals remain persistently uninfected. Such exposed uninfected (EU) people show evidence of HIV-1–specific T cell immunity and, in rare cases, selective resistance to infection by macrophage-tropic strains of HIV-1. The latter has been associated with a 32–base pair deletion in the C–C chemokine receptor gene CCR-5, the major coreceptor of macrophage-tropic strains of HIV-1. We have undertaken an analysis of the HIV-specific T cell responses in...

  9. La prevención de accidentes (2

    Directory of Open Access Journals (Sweden)

    Chinchilla, M.

    1966-03-01

    Full Text Available Everyone prefers to work in those organizations where their dignity of human beings is respected. One of the most efficient means at the disposal of any firm, to improve the morale of the individual employees, and to establish a spirit of cooperation between the individual and the firm, is to set up a program of accident benefit. It will avoid direct and indirect losses due to working accidents, as analyzed in a previous article, and it will make it possible to improve total performance of each worker, since he will work in a more favorable environment, free from worry about potential danger to his person. It is almost impossible to describe in detail all those items that should be taken into account in a safety program. None the less, and as an indication of their diversity, some sources of danger are mentioned in this chapter, which are closely connected with human safety, such as public curiosity, travelling from one place to another, cleanliness and order.Todas las personas prefieren desempeñar sus tareas en aquellas organizaciones que tienen hacia ellos las consideraciones correspondientes a un ser humano. Uno de los medios más eficaces a disposición de cualquier empresa para elevar la moral del individuo y para crear un lazo de cooperación común entre el individuo y la empresa, es la de llevar a cabo un programa de prevención de accidentes, programa que redundará en el doble fruto: evitar las pérdidas directas e indirectas causadas por los accidentes de trabajo que se detallaron en un trabajo anterior, y conseguir aumentar el rendimiento del operario al hacerle un ambiente más grato por la preocupación que se demuestra hacia su persona. Es casi imposible detallar todos aquellos puntos que se deben tener en cuenta en un programa de seguridad; sin embargo, y como exponente de su diversidad, se señalan en este capítulo algunas causas, que, sin estar ligadas directamente con el trabajo individual, no obstante se encuentran

  10. Hipotermia accidental secundaria a brote de psoriasis generalizada Accidental hypothermia due to generalized psoriasis

    Directory of Open Access Journals (Sweden)

    O. Agudo

    2004-04-01

    Full Text Available La hipotermia accidental es una alteración de la termorregulación corporal, definida como una temperatura central igual o inferior a 35ºC. Según la intensidad se puede clasificar en ligera (35-32,2ºC, moderada (32,2-28ºC y grave (The accidental hypothermia is a disorder of corporal termoregulation, defined as a central temperature below 35ºC. According to the intensity may be classified in mild (35-32.2 ºC, moderate (32.2-28ºC and severe (below 28ºC. The most frequent causes are the exposure to cold, use of depressant drugs of central nervous system and hypoglycemia, although there are other less frequent. We present a case of moderate hypothermia due to generalized psoriasis which required admission in the Intensive Care Unit of Hospital García Orcoyen. The termoregulation, pathogenesis, pathophysiology, diagnosis and management of accidental hypothermia are reviewed.

  11. Study of TSL and OSL properties of dental ceramics for accidental dosimetry applications

    Energy Technology Data Exchange (ETDEWEB)

    Veronese, Ivan, E-mail: ivan.veronese@unimi.i [Dipartimento di Fisica, Universita degli Studi di Milano and INFN Sezione di Milano, via Celoria 16, 20133 Milano (Italy); Galli, Anna [CNR-INFM, via Cozzi 53, 20125 Milano (Italy); Dipartimento di Scienza dei Materiali, Universita degli Studi di Milano Bicocca and INFN Sezione di Milano Bicocca, via Cozzi 53, 20125 Milano (Italy); Cantone, Marie Claire [Dipartimento di Fisica, Universita degli Studi di Milano and INFN Sezione di Milano, via Celoria 16, 20133 Milano (Italy); Martini, Marco [Dipartimento di Scienza dei Materiali, Universita degli Studi di Milano Bicocca and INFN Sezione di Milano Bicocca, via Cozzi 53, 20125 Milano (Italy); Vernizzi, Fabrizio; Guzzi, Gianpaolo [Italian Association for Metals and Biocompatibility Research - A.I.R.M.E.B., Milan (Italy)

    2010-01-15

    Interest is increasing in the development of new methodologies for accidental dose assessment, exploiting the luminescence and dosimetric properties of objects and materials which can be usually found directly on exposed subjects and/or in the contaminated area. In this work, several types of ceramics employed for dental prosthetics restoration, including both innovative materials used as sub-frames for the construction of the inner part of dental crowns (core), and conventional porcelains used for the fabrication of the external layer (veneer), were investigated with regard to their thermally and optically stimulated luminescence (TSL and OSL respectively) properties, in view of their potential application in accidental dosimetry. The sensitivity to ionizing radiation proved to strongly depend on the type and brand of ceramic, with minimum detectable dose ranging from few mGy up to several tens of mGy. A linear dose-response was observed for most of the samples. However, the luminescence signals were characterised by a significant fading, which has to be taken into account for a reliable accidental dose assessment after a radiation exposure event.

  12. Accidental hanging: a novel mobile suspension apparatus partially hidden inside the clothes.

    Science.gov (United States)

    Kodikara, Sarathchandra

    2012-12-01

    Accidental hanging is uncommon. An immobile/fixed and exposed suspension apparatus is seen in almost all cases of hanging. A 50-year-old man, who was drunk, was trying to steal an iron rod by hiding it under his clothing. To secure hiding, he attached it to his body by a loose ligature around the neck, the waist belt of the sarong, and another band around the waist and by his underwear. Sometime later, because of ethanol intoxication, he fell asleep in the sitting position. While he was sitting on the floor, the iron rod was lifted up accidentally, and its upper end was wedged against the wall behind the victim, and the lower end was fixed against the floor. When he fell asleep, the weight of the tilted head acted as the constricting force compressing the neck by the ligature that was used to attach the iron rod to the neck. The cause of death was concluded as hanging in a man with ethanol intoxication. This case highlights a novel mobile suspension apparatus partially hidden inside the clothes, in a case of accidental hanging. A similar case has not been reported in the forensic literature.

  13. Orofacial manifestations from accidental exposure to caesium 137 in Goiania, Brazil.

    Science.gov (United States)

    Gomes, M A; Wascheck, C de C; Scully, C; Almeida, O de P; Bozzo, L

    1990-08-01

    The accidental close exposure of over 200 adults and children to a caesium-137 (137Cs) source in Goiania, Brazil in 1987 produced significant short-term morbidity in about 50 patients, and four deaths within a few weeks. Some 57% of those maximally exposed to radiation, developed orofacial lesions, notably purpura, spontaneous bleeding, ulcers and/or acute candidiasis. These lesions were probably mainly the consequences of depression of bone marrow elements by the radionuclide. Though the oral lesions that may follow iatrogenic exposure to ionizing radiation are well recognized this appears to be the first report on the oral sequelae of a serious radiation accident.

  14. Patologías mentales derivadas de los accidentes de tránsito

    OpenAIRE

    2008-01-01

    Toda persona que se expone a un hecho traumático puede reaccionar de diversas maneras. En este artículo se revisan los conceptos de algunas enfermedades mentales relacionadas con accidentes de tránsito basadas en las Clasificaciones Nosográfias Internacionales DSM-IV y CIE 10.Any person exposed to a traumatic event can react in different ways. This article checks the concepts of some mental illnesses related to traffic accidents based on the international classifications (DSM-IV and ICD 10).

  15. Patologías mentales derivadas de los accidentes de tránsito

    Directory of Open Access Journals (Sweden)

    Ginette Campos Villalobos

    2008-09-01

    Full Text Available Toda persona que se expone a un hecho traumático puede reaccionar de diversas maneras. En este artículo se revisan los conceptos de algunas enfermedades mentales relacionadas con accidentes de tránsito basadas en las Clasificaciones Nosográfias Internacionales DSM-IV y CIE 10.Any person exposed to a traumatic event can react in different ways. This article checks the concepts of some mental illnesses related to traffic accidents based on the international classifications (DSM-IV and ICD 10.

  16. Biological dosimetry for the victim accidentally exposed to 192Ir radiation source at "5.7" accident in Nanjing%南京“5.7”192Ir源放射事故患者的生物剂量估算

    Institute of Scientific and Technical Information of China (English)

    戴宏; 刘玉龙; 王优优; 冯骏超; 赵骅; 刘青杰; 郭凯琳

    2016-01-01

    Objective To use three different methods in attempt to estimate the biological dose of the patient partially exposed to 192Ir source at " 5.7" accident in Nanjing,so as to provide dosimetric information for clinical remedy of exposed patients in the emergency of a nuclear accident.Methods Peripheral blood samples were collected on days 5 after exposure.The biological dose was estimated by the yields of dicentrics plus rings (" dic + r"),cytokinesis-block micronuclei (CBMN) assay and nucleoplasmic bridge plus FHC (NPB + FHC).The homogeneity of radiation exposure was examined by Poisson distribution of dicentrics.Results By using three different methods,the whole body equivalent dose was "dic + r" estimated to be 1.51 Gy (95% CI 1.40-1.61),1.47 Gy (95% CI 1.36-1.60) by CBMN and 1.30 Gy (95% CI 1.00-1.60) by NPB + FHC,respectively.A non-poisson distribution was also detected,suggesting partial body radiation exposure.Conclusions The estimated whole body equivalent dose ot a non-uniform radiation exposure was consistent with clinical diagnosis,suggesting that the yields of " dic + r",CBMN,as well as NPB + FHC,are efficient approaches to the estimation of biological doses.%目的 用3种方法估算南京“5.7”192Ir源放射事故患者的生物剂量,为核与辐射事故受照者的临床救治提供剂量资料.方法 受照后第5天采集患者外周血,分别进行外周血淋巴细胞染色体“双着丝粒+环”(“dic+r”)畸变分析、胞质分裂阻滞微核(CBMN)分析、核质桥(NPB+FHC)分析,并估算生物剂量.用双着丝粒畸变在细胞间的泊松分布情况检验照射的均匀性.结果 3种方法估算的该患者受到的一次全身等效剂量分别为“dic+r”畸变分析1.51 Gy (95% CI1.40~1.61),CBMN分析1.47 Gy(95% CI 1.36~1.60),NPB+ FHC分析1.30 Gy(95% CI1.00~1.60).泊松分布检验结果显示,该患者“dic+r”畸变偏离泊松分布,受到了不均匀照射.结论 外周血淋巴细胞染色体“dic

  17. Long-term follow-up study on reproductive and endocrine function in six victims accidentally exposed to 60 Co radiation%6名钴-60源辐射事故受照者生殖及内分泌功能远期效应随访

    Institute of Scientific and Technical Information of China (English)

    赵凤玲; 傅宝华; 吕玉民; 吴艳延; 邢志伟; 姜恩海; 姜梅玲; 于程程

    2014-01-01

    目的:了解钴-60(60Co)源辐射事故对受照者生殖及内分泌功能的远期效应。方法对河南省1999年4月26日60 Co源辐射事故6名受照者进行为期15年的生殖及内分泌功能远期效应医学观察。重点询问受照者婚育史及女性月经史;采用彩色多普勒超声诊断仪(以下简称“彩超”)检查受照者子宫、卵巢和甲状腺;检测其周围血血清生殖激素和甲状腺功能指标,并检测男性受照者精液常规。结果成年女性“梅”受照后出现放射性闭经,受照后2年子宫和卵巢明显缩小,生殖激素雌二醇和孕酮水平下降,卵泡刺激素( FSH)和黄体生成素( LH)水平升高。8岁男童“旺”受照后随访期间生殖器官发育正常,精液常规和生殖激素水平正常,婚后生育1健康男孩。成年男性“天”、“勇”、“民”和“义”受照后性欲无明显改变,受照后3个月精子均明显减少或缺乏,精子活动率下降,受照后6个月和1年精子均为0,受照后2年开始恢复;受照后1年“天”、“民”、“义”FSH均出现一过性升高,“民”LH出现一过性升高,但该时间点上述4名成年男性受照者睾酮均正常。有5名受照者于受照后15年进行彩超检查,其中“梅”、“天”和“民”检出甲状腺结节,“旺”和“义”甲状腺正常。“梅”受照后11、13和15年促甲状腺素水平升高,三碘甲状腺原氨酸和甲状腺素水平正常;其他5名受照者甲状腺功能正常。结论60 Co源电离辐射可损害受照者生殖能力,导致其甲状腺功能改变。性腺和甲状腺急性放射病患者远期随访观察应重点关注的靶器官。%Objective To explore the long-term effects of radiation on reproductive and endocrine function in persons exposed to 60 Co in the radiation source accident .Methods Fifteen-year-long long-term medical follow-up observation on the reproductive

  18. El accidente de trabajo. Concepto legal y jurisprudencia

    OpenAIRE

    García Romero, José Daniel

    2015-01-01

    El trabajo final de grado versa sobre el concepto de accidente de trabajo que da la jurisprudencia a través de las diferentes sentencias del Tribunal Supremo en la Sala de lo Social, y de los diferentes Tribunales Superiores de Justicia. Analizaremos en profundidad que características tienen que concurrir para que sea considerado como tal, analizando los diferentes supuestos de accidente de trabajo como el accidente in itinere, en misión, etc. También hemos tratado las diferentes contingencia...

  19. Estudo sobre os acidentes de trabalho com exposição aos líquidos corporais humanos em trabalhadores da saúde de um hospital universitário Estudio sobre los accidentes de trabajo con exposicíon a líquidos corporales humanos en trabajadores de la salud de un hospital universitario Study of work accidents related to human body fluids exposure among health workers at a university hospital

    Directory of Open Access Journals (Sweden)

    Ana Cristina Balsamo

    2006-06-01

    Full Text Available Este estudo descritivo exploratório, de abordagem quantitativa, teve como objetivos caracterizar os trabalhadores do Hospital Universitário da Universidade de São Paulo que sofreram acidente de trabalho com exposição aos líquidos corporais humanos, e avaliar o protocolo de atendimento aos acidentados. A população consistiu de 48 trabalhadores que sofreram acidente, no período de julho de 2000 a junho de 2001. Para a coleta dos dados, foi elaborado um formulário e realizada entrevista. Os resultados mostraram que os trabalhadores do Departamento de Enfermagem foram os que apresentaram maior risco desses acidentes e 87,50% ocorreram com os materiais perfurocortantes. Quanto à situação/atividade, relacionada ao acidente, os trabalhadores informaram que 25% foram devido ao "ato inadequado durante a realização do procedimento" 19,64% dos trabalhadores referiram que o acidente simplesmente "aconteceu" e 29,17% responderam que não tinham sugestões. Este estudo forneceu ferramentas importantes para a revisão e elaboração de estratégias de prevenção dos acidentes com exposição aos líquidos corporais humanos.Este estudio tuvo como objetivos caracterizar a los trabajadores que sufrieron accidente de trabajo con exposición a líquidos corporales humanos y evaluar el procedimiento de atención a los accidentados. La población estudiada fue de 48 trabajadores que sufrieron accidentes, en el período de julio de 2000 hasta junio de 2001. Para la recogida de datos fue elaborado un formulario y realizada una entrevista. Los resultados mostraron que los trabajadores del Departamento de Enfermería fueron los que presentaron mayor riesgo con relación a estos accidentes y que el 87,50% ocurrió con materiales punzantes o cortantes. Respecto a la situación/actividad relacionada con el accidente, los trabajadores informaron que el 25% fue debido a "acción inadecuada durante la realización del procedimiento", el 19,64% de los

  20. The Artificial, the Accidental, the Aesthetic…

    Directory of Open Access Journals (Sweden)

    Nicole Koltick

    2015-11-01

    Full Text Available How do we define, discuss or assess aesthetics within a contemporary philosophical framework? The indefiniteness that accompanies attempts to formalize a definition of the aesthetic is a primary focus of this paper. This lack of a definition has occupied philosophers for hundreds of years in attempts to delineate the boundaries of an elusively formless concept. This formlessness speaks to the incredibly evasive character of such a pervasive feature recognized in both natural and artificial systems, agents and artefacts. With the rapid growth of artificially intelligent systems and an astounding diversity in computational creativity, in what ways may we approach aesthetics? How is the aesthetic recognized, determined and produced? This paper seeks to critically engage issues of non-human agency, inter-object relations, and aesthetic theory in relation to computational entities and autonomous systems. The ability of these systems to operate outside of human cognitive limitations including thought patterns and constructions which may preclude alternative aesthetic outcomes, afford them in some ways limitless potential in relation to aesthetics. The designation of the accidental or provisional is utilized as an alternative approach to the production and assessment of aesthetic occurrences of the non-human.

  1. Presentismo: potencialidad en accidentes de salud

    Directory of Open Access Journals (Sweden)

    Grettchen Flores-Sandí

    2006-03-01

    Full Text Available El concepto de salud ha sobrepasado el entorno propiamente sanitario y cada vez más, tiene otras implicaciones sociales, la institución de salud es hoy en día una actividad compleja donde no solamente se gestiona la prevención y tratamiento de las enfermedades de los usuarios sino al recurso humano encargado de su atención. Asimismo en la actualidad se reconoce la importancia del recurso humano para la organización y surge el concepto de "presentismo", referido a aquellos trabajadores que sufren enfermedades que los obligarían a ausentarse del trabajo pero que se presentan a trabajar sin cumplir eficazmente sus funciones. Al respecto y en relación con el presentismo, se debe tomar en cuenta que los efectos adversos o accidentes durante la atención de servicios de salud se encuentran asociados a factores fisiológicos, psicológicos y ambientales e implican desde el punto de vista administrativo, una falla en la productividad, que afecta tanto al usuario del servicio como al trabajador. Se debe considerar que este grupo profesional se ubica entre los grupos de riesgo del presentismo y que con el fin de administrar y reducir el presentismo se requieren estrategias preventivas por parte de la gerencia de salud.

  2. Tuberculosis cutánea por inoculación accidental Cutaneous tuberculosis accidental inoculation

    Directory of Open Access Journals (Sweden)

    María Ascensión Maestre Naranjo

    2009-09-01

    Full Text Available Caso clínico de una microbióloga con amplia experiencia, que sufre una inoculación accidental al manipular una cepa pura de Mycobacterium tuberculosis. Se pincha en la cara lateral externa de la falange distal del dedo índice, atravesando el guante con la aguja contaminada. (Imagen 1. La trabajadora procede de forma inmediata a la limpieza de la herida. El Servicio de Prevención, registra la inoculación como accidente de trabajo. A las tres semanas del accidente, aparece en el lugar de la inoculación una pápula eritematosa levemente dolorosa a la presión que va creciendo hasta alcanzar un tamaño de 1,5-2 cm., sin adenopatías axilares, ni clínica general. (Imagen 2 Se procede a la exéresis y biopsia de la lesión. Informe anatomopatológico: Inflamación crónica granulomatosa tuberculoide muy sugestiva de tuberculosis cutánea. Microbiología: dudosos bacilos ácido alcohol resistentes (BAAR Cultivo: positivo a Mycobacterium tuberculosis. Ambas cepas presentan la misma identidad. Diagnóstico: tuberculosis cutánea. El SPRL realiza la comunicación de Enfermedad Profesional según el RD 1299/2006, de 10 de diciembre. Se realiza valoración y seguimiento en el Servicio de Medicina Interna, iniciando tratamiento de tuberculosis.Clinical case of a microbiologist with wide experience, which is inoculated accidental when Mycobacterium's pure strain manipulates tuberculosis; it (she pricks itself in the lateral external face of the phalanx distal of the forefinger, crossing the glove with the contaminated needle. Immediate treatment of the wound. The Service of Prevention, he registers the inoculation as accident of work. To three weeks a slightly painful pápula eritematosa appears in the place of the inoculation to the pressure that is growing until a size reaches 1,5-2 cm., without adenopatías axyllaris, not general clinic. Exéresis and biopsy of the same one, pathological anatomy: chronic inflammation very suggestive granulomatosa

  3. Outcome of Accidental Exposure Prone to Blood Borne Viral Infections in an Educational Hospital

    Directory of Open Access Journals (Sweden)

    Shahnaz Sali

    2016-04-01

    Full Text Available Background: The risk for transmission of blood-borne viruses (BBVs such as Human immunodeficiency virus (HIV, hepatitis B virus (HBV and hepatitis C virus (HCV due to occupational exposure is a major concern in the health care setting.Materials and Methods: This study among 337 health care workers (HCWs accidentally exposed to BBVs was carried out from January 2009 to March 2015. The data were reviewed in labbafinejhad hospital, Tehran, Iran.Results: 4 HCWs had exposure to HBS Ag positive, which HBS antibody titer of them was higher than 10 mlu/ml, 6 HCWs were exposed to HCV seropositive patients underwent laboratory investigations for  HCV-antibody on 4,12, 24 weeks that results were negative. 3 cases had exposure to HIV seropositive patients which received standard antiretroviral post exposure prophylaxis.Conclusion: Timely performance for PEP (Post Exposure Prophylaxis reducing BBVs transmission among HCWs.prophylaxis. Conclusions: Timely performance for  PEP(Post Exposure Prophylaxis reducing BBVs transmission among HCWs.Key words: Outcome; Accidental Exposure; Blood Borne Viral Infections

  4. Epidemiology of Munchausen syndrome by proxy, non-accidental poisoning, and non-accidental suffocation.

    Science.gov (United States)

    McClure, R J; Davis, P M; Meadow, S R; Sibert, J R

    1996-07-01

    A two year prospective study was performed to determine the epidemiology of Munchausen syndrome by proxy, non-accidental poisoning, and non-accidental suffocation in the UK and the Republic of Ireland. Cases were notified to the British Paediatric Association Surveillance Unit from September 1992 to August 1994 if a formal case conference had been held for the first time during that period to discuss any of the above conditions. A total of 128 cases were identified: 55 suffered Munchausen syndrome by proxy alone, 15 poisoning, and 15 suffocation; 43 suffered more than one type of abuse. The majority of children were aged under 5 years, the median age being 20 months. On 85% of occasions the perpetrator was the child's mother. In 42% of families with more than one child, a sibling had previously suffered some form of abuse. Eighty five per cent of notifying paediatricians considered the probability of their diagnosis as virtually certain before a case conference was convened. The commonest drugs used to poison were anticonvulsants; opiates were the second commonest. Sixty eight children suffered severe illness of whom eight died. The combined annual incidence of these conditions in children aged under 16 years is at least 0.5/100,000, and for children aged under 1, at least 2.8/100,000.

  5. Historical Doses from Tritiated Water and Tritiated Hydrogen Gas Released to the Atmosphere from Lawrence Livermore National Laboratory (LLNL). Part 5. Accidental Releases

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, S

    2007-08-15

    Over the course of fifty-three years, LLNL had six acute releases of tritiated hydrogen gas (HT) and one acute release of tritiated water vapor (HTO) that were too large relative to the annual releases to be included as part of the annual releases from normal operations detailed in Parts 3 and 4 of the Tritium Dose Reconstruction (TDR). Sandia National Laboratories/California (SNL/CA) had one such release of HT and one of HTO. Doses to the maximally exposed individual (MEI) for these accidents have been modeled using an equation derived from the time-dependent tritium model, UFOTRI, and parameter values based on expert judgment. All of these acute releases are described in this report. Doses that could not have been exceeded from the large HT releases of 1965 and 1970 were calculated to be 43 {micro}Sv (4.3 mrem) and 120 {micro}Sv (12 mrem) to an adult, respectively. Two published sets of dose predictions for the accidental HT release in 1970 are compared with the dose predictions of this TDR. The highest predicted dose was for an acute release of HTO in 1954. For this release, the dose that could not have been exceeded was estimated to have been 2 mSv (200 mrem), although, because of the high uncertainty about the predictions, the likely dose may have been as low as 360 {micro}Sv (36 mrem) or less. The estimated maximum exposures from the accidental releases were such that no adverse health effects would be expected. Appendix A lists all accidents and large routine puff releases that have occurred at LLNL and SNL/CA between 1953 and 2005. Appendix B describes the processes unique to tritium that must be modeled after an acute release, some of the time-dependent tritium models being used today, and the results of tests of these models.

  6. Non-accidental collision followed by dental trauma: associated factors.

    Science.gov (United States)

    Ramos-Jorge, Maria Letícia; Tataounoff, Juliana; Corrêa-Faria, Patrícia; Alcântara, Carlos Eduardo Pinto; Ramos-Jorge, Joana; Marques, Leandro Silva

    2011-12-01

    The aim of the present cross-sectional survey was to assess factors associated with non-accidental collision followed by dental trauma among adolescents in the city of Diamantina, Brazil. A total of 387 students from 12 to 15 years of age (mean = 14 SD = 0.9) were randomly selected. The study was carried out in two stages. Firstly, data were collected through dental examinations of permanent incisors. Secondly, a thorough interview was held with 85 adolescents who exhibited dental trauma in the dental examinations. The interview consisted of a detailed description of the incident and physical environment in which it occurred. Descriptive analysis and the chi-square test (P 3 mm (P = 0.007) and inadequate lip coverage (P = 0.013). Analysis of the event revealed that 22.3% of the cases of dental trauma occurred because of non-accidental collision. Non-accidental collision followed by injury occurred mainly at school (P concrete, tiled or ceramic floor (P = 0.001). No statistically significant associations were found between non-accidental collision and gender, age or mother's schooling. It was concluded that the non-accidental collisions happened especially at school and in indoor environments with a concrete, tiled or ceramic floor.

  7. Amputación corporal por accidente de trabajo en auxiliar de enfermería

    OpenAIRE

    Alexander Finol Muñoz; Gloria Ortega Marín; Julián Domínguez Fernández; Johanna Rivero Colina; Manuel Usero Fernández; Miguel Espejo García

    2014-01-01

    Los auxiliares de enfermería son un rango profesional expuesto a múltiples riesgos por las actividades inherentes a su trabajo, expuestos constantemente a sustancias desinfectantes que sin el uso apropiado de equipos de protección individual, puede provocar efectos adversos y lesiones en el trabajador. Caso Clínico: Mujer de 51 años de edad, auxiliar de enfermería, con antecedentes de Diabetes Mellitus tipo I y Síndrome de Túnel Carpiano. Presenta derrame accidental de líquido mientras llenab...

  8. Correcting for accidental correlations in saturated avalanche photodiodes

    CERN Document Server

    Grieve, James A; Tang, Zhongkan; Ling, Alexander

    2015-01-01

    In this paper we present a high-level numerical model for estimating rates of accidental correlations between a pair of passively quenched Geiger mode avalanche photodiodes operating in the saturated regime. By considering the recovery time of both the diodes and the detection circuit we introduce the concept of an "effective duty cycle" and show that it may be estimated by numeric simulation. The impact of effective duty cycle on the observed accidental rate is examined and we demonstrate that the updated model leads to an improved correction factor in actual experiments. This will improve the signal-to-noise ratio in applications depending on correlation measurements.

  9. Perfil del trauma maxilofacial en accidentes de bicicleta

    OpenAIRE

    Guadalupe Asunción Ramírez Roa; María Guadalupe Suárez-Moreno; Florentino Puerto-Álvarez; Heber Félix Quiroga-Vía; Jesús Arenas-Osuna; Bertha Vivanco-Cedeño

    2005-01-01

    Objetivo: conocer el perfil traumatológico maxilofacial, concomitante y manejo, de las personas que sufrieron accidentes de bicicleta. Se identificaron variables como edad, sexo, mecanismo, lugar, mes, patrones de lesiones, sintomatología, lapso de atención, turno, especialidad y tratamientos. Diseño: exploratorio, descriptivo, analítico, retrospectivo. Material y métodos: se censaron todos los pacientes con lesiones maxilofaciales por accidentes de bicicleta, de las notas médicas del Servici...

  10. ACCIDENTAL DEATHS DUE TO ELECTROCUTION DURING AMATEUR ELECTRO - FISHING

    Directory of Open Access Journals (Sweden)

    Ajay

    2013-11-01

    Full Text Available ABSTRACT: Electro - fishing (passing electricity through water to catch fish requires sophisticated equipment. While this method is commonly employed b y scientists for survey and fisheries management, a crude and illegal form electro - fishing is employed in Kerala for catching fish from water bodies. This can result in accidental electrocution and even fatalities. Even though they are rare, forensic patho logists in Kerala do come across such deaths from time to time. 8 cases of accidental death which occurred during electro - fishing are discussed here.

  11. Accidentes laborales, medicamentos y hábitos de salud

    OpenAIRE

    Esteban Martín, María Ángeles

    2015-01-01

    El presente estudio está dirigido a analizar la posible asociación con el accidente de trabajo del tipo y cantidad de medicamentos que consumen los trabajadores de forma crónica y/o aguda antes de acudir a nuestra consulta, de las enfermedades crónicas y/o agudas que padecen y de otros hábitos de consumo (alcohol y drogas). La salud laboral es un problema prioritario. El objetivo será promover la salud de los trabajadores y tratar de disminuir la incidencia de accidentes laborales. E...

  12. Triage and management of accidental laboratory exposures to biosafety level-3 and -4 agents.

    Science.gov (United States)

    Jahrling, Peter; Rodak, Colleen; Bray, Mike; Davey, Richard T

    2009-06-01

    The recent expansion of biocontainment laboratory capacity in the United States has drawn attention to the possibility of occupational exposures to BSL-3 and -4 agents and has prompted a reassessment of medical management procedures and facilities to deal with these contingencies. A workshop hosted by the National Interagency Biodefense Campus was held in October 2007 and was attended by representatives of all existing and planned BSL-4 research facilities in the U.S. and Canada. This report summarizes important points of discussion and recommendations for future coordinated action, including guidelines for the engineering and operational controls appropriate for a hospital care and isolation unit. Recommendations pertained to initial management of exposures (ie, immediate treatment of penetrating injuries, reporting of exposures, initial evaluation, and triage). Isolation and medical care in a referral hospital (including minimum standards for isolation units), staff recruitment and training, and community outreach also were addressed. Workshop participants agreed that any unit designated for the isolation and treatment of laboratory employees accidentally infected with a BSL-3 or -4 pathogen should be designed to maximize the efficacy of patient care while minimizing the risk of transmission of infection. Further, participants concurred that there is no medically based rationale for building care and isolation units to standards approximating a BSL-4 laboratory. Instead, laboratory workers accidentally exposed to pathogens should be cared for in hospital isolation suites staffed by highly trained professionals following strict infection control procedures.

  13. Using Microsoft Excel to compute the 5% overall site X/Q value and the 95th percentile of the distribution of doses to the nearest maximally exposed offsite individual (MEOI).

    Science.gov (United States)

    Vickers, Linda D

    2010-05-01

    This paper describes the method using Microsoft Excel (Microsoft Corporation One Microsoft Way Redmond, WA 98052-6399) to compute the 5% overall site X/Q value and the 95th percentile of the distribution of doses to the nearest maximally exposed offsite individual (MEOI) in accordance with guidance from DOE-STD-3009-1994 and U.S. NRC Regulatory Guide 1.145-1982. The accurate determination of the 5% overall site X/Q value is the most important factor in the computation of the 95th percentile of the distribution of doses to the nearest MEOI. This method should be used to validate software codes that compute the X/Q. The 95th percentile of the distribution of doses to the nearest MEOI must be compared to the U.S. DOE Evaluation Guide of 25 rem to determine the relative severity of hazard to the public from a postulated, unmitigated design basis accident that involves an offsite release of radioactive material.

  14. The accidental overexposures; Les surexpositions accidentelles

    Energy Technology Data Exchange (ETDEWEB)

    Nenot, J.C.

    1993-03-01

    The radioisotope or ionizing radiation medical or industrial use may generate accidents where human beings are exposed to very high doses. The accident frequency is increasing quickly because of the industrial source use development. The accidents don`t catch only the plant or hospital staffs but also public people. The serious accidents result from conception errors, bad installation maintenance, lack or not enough staff training, transgression of safety processes. The accidents happen in not very specialized firms. Those resulting from energy production reactors are very seldom except for Chernobyl or military submarines. In the medical or hospital installations, accidents may affect the staffs or the patients. Most of the accidents could have been avoided by the simple respect of the simple surety duties. The follow up and analysis of serious accidents can bring an effective collaboration to the prevention. 78 refs., 3 annexes., 14 tabs., 17 figs.

  15. The Accidental Transgressor: Morally-Relevant Theory of Mind

    Science.gov (United States)

    Killen, Melanie; Mulvey, Kelly Lynn; Richardson, Cameron; Jampol, Noah; Woodward, Amanda

    2011-01-01

    To test young children's false belief theory of mind in a morally relevant context, two experiments were conducted. In Experiment 1, children (N=162) at 3.5, 5.5, and 7.5 years of age were administered three tasks: prototypic moral transgression task, false belief theory of mind task (ToM), and an "accidental transgressor" task, which measured a…

  16. 49 CFR 192.751 - Prevention of accidental ignition.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Prevention of accidental ignition. 192.751 Section 192.751 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Maintenance § 192.751 Prevention...

  17. An accidental sect: how war made belief in Sierra Leone

    NARCIS (Netherlands)

    Richards, P.

    2006-01-01

    Idealists consider beliefs cause wars. Realists consider wars cause beliefs. The war in Sierra Leone offers some scope to test between these two views. The main rebel faction, the Revolutionary United Front (RUF) was, sociologically speaking, an accidental sect. It lost its original ideologues at an

  18. Quality control for handling of accidental blood exposures.

    NARCIS (Netherlands)

    Wijk, P.T. van; Pelk-Jongen, M.; Wijkmans, C.; Voss, A.; Schneeberger, P.M.

    2006-01-01

    A regional counselling service was established to handle all accidental blood exposures using a standardized protocol. Levels of risk were assessed using an algorithm. Accidents that posed a risk for the transmission of hepatitis B (HBV), hepatitis C (HCV) and human immunodeficiency virus (HIV) were

  19. Responsabilidad del empleador por accidentes de trabajo y enfermedades profesionales

    Directory of Open Access Journals (Sweden)

    Cristina Mangarelli

    2014-01-01

    Full Text Available Introducción. 1. Responsabilidad del “empleador” por accidentes de trabajo y enfermedades profesionales. Noción. 2. La indemnización “tarifada”. Fundamento de su procedencia 3. Responsabilidad del empleador por accidentes de trabajo o enfermedades profesionales en la ley uruguaya (ley Nº 16.074. 4. La “ampliación” de la responsabilidad del empleador por el derecho común en el derecho uruguayo (artículo 7 ley Nº 16.074. 5. Requisitos para la ampliación de la responsabilidad patronal: culpa grave en el incumplimientode normas de seguridad y prevención. 6. La culpa grave. Concepto. 7. El modelo del hombre a tener en cuenta en la “culpa grave” no es el del buen padre de familia. 8. El grado de la culpa no puede ser medido por el resultado del accidente. 9. Se aplican las eximentes de la responsabilidad civil. 10. Distintos ámbitos de la responsabilidad patronal por accidentes de trabajo o enfermedades profesionales: A ante la víctima o los derecho-habientes; B ante el Banco de Seguros del Estado; C ante el Ministerio de Trabajo ySeguridad Social. 11. Recupero del BSE en caso de culpa grave en el incumplimiento de normas de seguridad y prevención. Requisitos 12. Responsabilidad del empleador en caso de accidente de trabajo o enfermedad profesional sufrido por un adolescente. Conclusiones.

  20. Developmental dental defects in children exposed to PCBs

    Energy Technology Data Exchange (ETDEWEB)

    Jan, J. [Ljubljana Univ. (Slovenia). Fac. of Medicine; Sovcikova, E.; Kovrizhnykh, I.; Wimmerova, S.; Trnovec, T. [Slovak Medical Univ., Bratislava (Slovakia). Inst. of Preventive and Clinical Medicine; Kocan, A. [Institute of Preventive and Clinical Medicine, Bratislava (Slovakia). Dept. of Toxic Organic Pollutants

    2004-09-15

    Developing enamel is sensitive to a wide range of local and systemic disturbances. Because of the absolute metabolic stability of its structure, changes in enamel during its development are permanent in nature. Polychlorinated biphenyls (PCB) have been shown to disturb tooth development in experimental animals, but only limited amounts of data exist on their adverse effects in humans. Dental changes such as mottled, chipped, carious, and neonatal teeth have been reported in accidentally exposed humans. Nevertheless, co-contamination with polychlorinated dibenzo-furans (PCDFs) was largely responsible for the overall toxicity4. Alaluusua et al. found that developmental dental defects were correlated with the total exposure to polychlorinated aromatic hydrocarbons via mother's milk. The correlation was strong with exposure to prevailing levels of polychlorinated dibenzo-p-dioxins (PCDD) and furans (PCDF) but weak with exposure to PCBs alone. In our previous study we have shown developmental dental defects in children exposed to PCBs alone6, suggesting that the developing human teeth are vulnerable to PCBs. In the Michalovce region of eastern Slovakia, PCBs from a chemical plant manufacturing Delors contaminated the surrounding district7. The total serum PCB levels in samples from the general population there exceeded by several times the background levels in subjects living in a comparable unexposed Svidnik district. PCB levels in breast milk samples in the Michalovce region were the highest in Slovakia. Levels of toxic polychlorinated aromatics (PCDFs, PCNs, and planar PCBs) in technical Delors were high. The aim of this study was to evaluate the effects of long-term exposure to PCBs, measured at the individual level, on developmental dental defects in children in eastern Slovakia.

  1. Reducing the loss of vaccines from accidental freezing in the cold chain: the experience of continuous temperature monitoring in Tunisia.

    Science.gov (United States)

    Lloyd, John; Lydon, Patrick; Ouhichi, Ramzi; Zaffran, Michel

    2015-02-11

    Accidental freezing of vaccines is a growing threat and a real risk for national immunization programs when the potency of many vaccines can be compromised if these are exposed to sub-zero temperatures in the cold chain. In Tunisia, this issue is compounded by using sub-standard domestic cold chain equipment instead of equipping the program with medical refrigerators designed specifically for storing vaccines and temperature sensitive pharmaceuticals. Against this backdrop, this paper presents the findings of a demonstration project conducted in Tunisia in 2012 that tested the impact of introducing several freeze prevention solutions to mitigate the risk of accidental freezing of vaccines. The main finding is that, despite the continued use of underperforming domestic refrigerators, continuous temperature monitoring using new technologies combined with other technological interventions significantly reduced the prevalence of accidental exposure to freezing temperatures. These improvements were noticed for cold chain storage at regional, district and health center levels, and during the transport legs that were part of the demonstration conducted in the regions of Kasserine in the South-Eastern part of Tunisia. Subsequent to introducing these freeze prevention solutions, the incidence of freeze alarms was reduced and the percent of time the temperatures dropped below the 2 °C recommended threshold. The incidence of freeze alarms at health center level was reduced by 40%. Lastly, the solutions implemented reduced risk of freezing during transport from 13.8% to 1.7%. Although the solution implemented is not optimal in the longer term because domestic refrigerators are used extensively in district stores and health centers, the risk of accidental freezing is significantly reduced by introducing the practice of continuous temperature monitoring as a standard. The management of the cold chain equipment was strengthened as a result which helps protect the potency of

  2. Accidental neutron dosimetry with human hair

    Science.gov (United States)

    Ekendahl, Daniela; Bečková, Věra; Zdychová, Vlasta; Bulánek, Boris; Prouza, Zdeněk; Štefánik, Milan

    2014-11-01

    Human hair contains sulfur, which can be activated by fast neutrons. The 32S(n,p)32P reaction with a threshold of 2.5 MeV was used for fast neutron dose estimation. It is a very important parameter for individual dose reconstruction with regards to the heterogeneity of the neutron transfer to the human body. Samples of human hair were irradiated in a radial channel of a training reactor VR-1. 32P activity in hair was measured both, directly by means of a proportional counter, and as ash dispersed in a liquid scintillator. Based on neutron spectrum estimation, a relationship between the neutron dose and induced activity was derived. The experiment verified the practical feasibility of this dosimetry method in cases of criticality accidents or malevolent acts with nuclear materials.

  3. Health care workers and AIDS: a differential study of beliefs and affects associated with accidental exposure to blood Profissionais de saúde e AIDS: um estudo diferencial sobre crenças e afetos associados à experiência de exposição acidental a material biológico potencialmente contaminado

    Directory of Open Access Journals (Sweden)

    Maria Rosa Rodrigues Rissi

    2005-02-01

    Full Text Available This study aimed to analyze affective and cognitive determinants of the professional work of individuals caring for patients with HIV/AIDS, in view of the risk and/or experience of accidental exposure to blood. We drew on the theoretical-methodological references of Fishbein & Ajzen and Maslow's theory. Fifty health care workers were evaluated using an attitudes questionnaire and a needs and motivations instrument. The research verified differences between answers by health care workers who had never suffered accidents and those who had already experienced accidental exposure to blood. Health care workers did their work activities motivated by the need for self-fulfillment and valued their own performance when they were able to meet the patients' emotional needs. Among health professionals who had never experienced accidental exposure to blood, the predominant beliefs was that patients feel remorse over having expose themselves to HIV. Accidental exposure to blood raises difficulties in personal life. Technical aspects are also associated with the possibility of accidental exposure to blood.O objetivo deste estudo foi analisar determinantes afetivos e cognitivos que influenciam o trabalho de profissionais que cuidam de pessoas vivendo com o HIV/ AIDS, frente ao risco ou experiência de exposição acidental a material biológico potencialmente contaminado (MBPC. Utilizou-se o referencial teórico metodológico de Fishbein-Ajzen e a teoria de Maslow, que propõe a hierarquia das necessidades humanas. Cinqüenta profissionais de saúde foram avaliados por meio de escalas de atitudes, e de um instrumento de avaliação de necessidades e motivações. Verificou-se a diferença entre as respostas de profissionais que nunca sofreram acidente e aqueles que já passaram pela experiência de acidente ocupacional. Os resultados indicam que os profissionais exercem suas atividades motivados pela necessidade de auto-realização e valorizam sua performance

  4. Inteligibilidade de fala com e sem ruído em indivíduos expostos à música eletrônica Speech intelligibility with and without noise in individuals exposed to electronic music

    Directory of Open Access Journals (Sweden)

    Jéssica Kuchar

    2010-06-01

    Full Text Available A audiometria é o principal meio pelo qual se avalia a audição, pois é um teste universal e padronizado. Os testes de fala são de difícil padronização devido às variáveis envolvidas, sendo de grande importância a aplicação destes na presença de ruído competitivo. OBJETIVO: Caracterizar a inteligibilidade de fala no silêncio e na presença de ruído competitivo, em indivíduos expostos à música eletronicamente amplificada. MATERIAL E MÉTODO: Foi realizado com 20 estudantes universitários apresentando limiares auditivos normais. O índice de reconhecimento de fala (IPRF foi realizado com quatorze horas de repouso acústico, logo após a exposição à música eletronicamente amplificada e novamente após repouso acústico, sendo obtido em três etapas: sem ruído competitivo, com a presença de ruído competitivo tipo Babble, em escuta monótica, na relação sinal-ruído de + 5 dB e com a relação sinal-ruído - 5 dB. RESULTADOS: Houve maior prejuízo no IPRF logo após a exposição à música e com ruído competitivo, e conforme a relação sinal/ruído diminui, houve piora no desempenho dos indivíduos no teste. CONCLUSÃO: A inclusão do uso de ruído competitivo nos testes de fala na rotina audiológica é importante, pois representa a real desvantagem vivenciada pelos indivíduos na escuta cotidiana.Audiometry is the main way with which hearing is evaluated, because it is a universal and standardized test. Speech tests are difficult to standardize due to the variables involved, their performance in the presence of competitive noise is of great importance. AIM: To characterize speech intelligibility in silence and in competitive noise from individuals exposed to electronically amplified music. MATERIAL AND METHOD: It was performed with 20 university students who presented normal hearing thresholds. The speech recognition rate (SRR was performed after fourteen hours of sound rest after the exposure to electronically

  5. El accidente de trabajo "in itinere" = Working in the accident "itinere"

    OpenAIRE

    Pinillas Carro, Pedro

    2015-01-01

    El trabajo aqu?? presentado aborda el estudio de los accidentes de trabajo, regulado al art??culo 115 Ley General de Seguridad Social, y m??s concretamente el accidente in itinere, claro est??, sin olvidar tampoco el accidente en misi??n. En la primera parte del trabajo, y una vez desarrollado el concepto de accidente de trabajo, el presente trabajo se centra en el estudio pormenorizado del accidente in itinere y sus requisitos (teleol??gico, topogr??fico, cronol??gico y mec??nico). Por otro ...

  6. Accidental Electric Shock during Pregnancy: Reflection on a Case

    Directory of Open Access Journals (Sweden)

    Johnny Awwad

    2013-10-01

    Full Text Available Objectives - Data on fetal effects following accidental electric shock during pregnancy are scarce. We report on a case of accidental maternal electric shock associated with benign fetal arrhythmia in a woman at 28 weeks' gestation. Study Design - Case report. Results - Although electrocution involving low-voltage, low-frequency current has been associated with fatal cardiac arrhythmias and conduction abnormalities, two protective parameters in the present case likely reduced the fetal injury: the dry skin at the site of current entry and the hand-to-hand pathway of current flow. Conclusion - Because the pathophysiology of electric injury is altered during pregnancy, assessment of fetal well-being should be prompted no matter how trivial an incident may appear.

  7. Accidental Electric Shock during Pregnancy: Reflection on a Case.

    Science.gov (United States)

    Awwad, Johnny; Hannoun, Antoine; Fares, Farah; Ghazeeri, Ghina

    2013-10-01

    Objectives Data on fetal effects following accidental electric shock during pregnancy are scarce. We report on a case of accidental maternal electric shock associated with benign fetal arrhythmia in a woman at 28 weeks' gestation. Study Design Case report. Results Although electrocution involving low-voltage, low-frequency current has been associated with fatal cardiac arrhythmias and conduction abnormalities, two protective parameters in the present case likely reduced the fetal injury: the dry skin at the site of current entry and the hand-to-hand pathway of current flow. Conclusion Because the pathophysiology of electric injury is altered during pregnancy, assessment of fetal well-being should be prompted no matter how trivial an incident may appear.

  8. Accidental degeneracy of double Dirac cones in a phononic crystal

    KAUST Repository

    Chen, Ze-Guo

    2014-04-09

    Artificial honeycomb lattices with Dirac cone dispersion provide a macroscopic platform to study the massless Dirac quasiparticles and their novel geometric phases. In this paper, a quadruple-degenerate state is achieved at the center of the Brillouin zone in a two-dimensional honeycomb lattice phononic crystal, which is a result of accidental degeneracy of two double-degenerate states. In the vicinity of the quadruple-degenerate state, the dispersion relation is linear. Such quadruple degeneracy is analyzed by rigorous representation theory of groups. Using method, a reduced Hamiltonian is obtained to describe the linear Dirac dispersion relations of this quadruple-degenerate state, which is well consistent with the simulation results. Near such accidental degeneracy, we observe some unique properties in wave propagating, such as defect-insensitive propagating character and the Talbot effect.

  9. Leading global projects for professional and accidental project leaders

    CERN Document Server

    Moran, Robert T

    2008-01-01

    This book is a must-read for anyone responsible for projects and initiatives that span functional and geographical divides. Authors Moran and Youngdahl bring extensive experience and learning from industry practice to present a clear and straightforward treatment of the leadership skills and knowledge required to lead projects that are global in nature. They have written the first book of its kind to address the three essential skills of global project leaders - strategic project management, project leadership, and cross-cultural leadership. The authors argue that global project leadership is an essential skill in our project-based world and that we are all either intentional or accidental project leaders. Intentional project leaders pursue formal project management education and even certification whereas accidental project leaders find themselves leading global projects and initiatives as a result of a special assignment or promotion. Moran and Youndahl have found that the vast majority of global projects ...

  10. D-transallethrin: An unusual agent for accidental poisoning

    OpenAIRE

    Vinod Kedari; Rajesh Kulkarni; Chhaya Valvi; Aarti Kinikar; Sandhya Khadse

    2016-01-01

    D-trans allethrin, a pyrethroid, is commonly used as a coil mosquito repellant. There are very few reports of human toxicity due to D-trans allethrin. We present the case of an 11-month-old boy who presented to us with excessive salivation, altered sensorium and convulsions following alleged accidental ingestion of a coil containing D-transallethrin. He required mechanical ventilation for a brief period and made a full recovery. Although rare, the possibility of pyrethroid poisoning should be...

  11. Accidental surface contamination - The effect on trace element analysis

    Energy Technology Data Exchange (ETDEWEB)

    Franklyn, C.B. E-mail: franklyn@aec.co.za; Ueckermann, H.; Merkle, R.K.W

    2001-07-01

    We discuss the accidental contamination of samples during a micro-PIXE study of Rh, Pd and Pt partition coefficients in the Fe-S and Ni-S systems. Trace amounts of Ni and Cu, mounted separately in epoxy as markers, were found to be present in various phases in the sections, sometimes selectively in specific mineral phases. This contamination is believed to result from polishing during preparation. Further surface contamination from conductive Ag paste was also observed.

  12. Accidental IV administration of epinephrine instead of midazolam at colonoscopy

    Directory of Open Access Journals (Sweden)

    Ahmed Gado

    2016-03-01

    Full Text Available Drug administration errors appear to be a major source of iatrogenic harm to hospitalized patients. They often, particularly in the case of epinephrine, have catastrophic consequences both for the patient and the well-meaning provider. The following incident is a medication error case report which illustrates one way that incorrect medication may be administered. IV epinephrine was accidentally administered instead of midazolam at colonoscopy.

  13. La prevención de accidentes (3

    Directory of Open Access Journals (Sweden)

    Chinchilla, M.

    1966-04-01

    Full Text Available The financial loss due to working accidents is very substantial, quite apart from the actual loss of human lives. Hence avoiding these accidents is a most important matter. The accident index in the various industries shows a rate of increase that is larger than should be the case in proportion to the development of the industries concerned, and the larger number of employees. The fact that these indexes are smaller in many countries, however, shows that these accidents can be considerably reduced if suitable measures are taken to avoid them. In chapter 2 of our magazine, issue no. 178, a variety of reasons were discussed that may originate accidents, although these causes are not directly linked to the accident itself. In this article mention is made of some of the measures that can be taken in the handling of cutting and welding equipment, and also of inflammable liquids, to prevent possible accidents.El peso de los accidentes de trabajo sobre la economía supone cantidades muy grandes que, independientemente del inestimable valor de una vida humana, realzan la importancia de la prevención de accidentes. Los índices de accidentes muestran en diferentes industrias un crecimiento mayor de lo que debería corresponder proporcionalmente, habida cuenta del crecimiento laboral. El hecho de que en distintos países los índices sean inferiores, demuestra que se pueden conseguir buenos frutos si se concede primordial importancia a que los trabajos se realicen con las debidas medidas de seguridad. En el Capítulo 2, número 178 de esta Revista, se detallaron diversas causas que pueden originar un accidente sin estar ligadas en forma directa con una tarea determinada. En el presente trabajo se indican algunas de las medidas que deben observarse en el manejo de los equipos de soldadura y corte, así como en el transvase de líquidos inflamables.

  14. "Dead in hot bathtub" phenomenon: accidental drowning or natural disease?

    Science.gov (United States)

    Satoh, Fumiko; Osawa, Motoki; Hasegawa, Iwao; Seto, Yoshihisa; Tsuboi, Akio

    2013-06-01

    Sudden death in a hot bathtub occurs frequently in Japan, particularly among elderly people. This retrospective report describes the epidemiologic circumstances and physical findings at autopsy. In total, 268 victims were found unconscious or dead during tub bathing. After postmortem examination, the manner of death was judged as natural cause in 191 (71.2%) and accidental drowning in 63 (23.5%) cases. Mean age (SD) was 72.1 (15.2) years with no significant difference between males and females. A seasonal difference was evident: the winter displayed the highest frequency. Drowning water inhalation, which was confirmed in 72% of victims, was absent in the others. The most common observations on postmortem examination were cardiac ischemic changes and cardiomegaly. Water inhalation signs were evident in a significantly fewer victims exhibiting these factors. In contrast, inhalational findings were observed more frequently in victims with other backgrounds such as alcohol intake, mobility disturbance, and history of epilepsy. Annual mortality in Japan from accidental drowning in persons aged older than 75 years is 33 deaths per 100,000 population. However, this number may be considerably underestimated as pathologists tend to regard lack of water inhalation as indicating a natural cause of death. Confusion in diagnosis remains consequent to the accidental and natural aspects of "dead in hot bathtub" phenomenon.

  15. Accidental falls involving medical implant re-operation.

    Science.gov (United States)

    Ong, Kevin L; Lau, Edmund; Moore, Tara; Heller, Michelle F

    2009-10-01

    Implantation of medical devices is becoming more prevalent, and as a result, a greater number of patients who fall accidentally are expected to have a medical implant. The Nationwide Inpatient Sample (NIS) was used to evaluate hospital admissions following accidental falls involving re-operation of existing medical implants (hip, knee, spine, and fracture fixation) from 1990 to 2005. From 1990 to 2005, hospitalisations due to accidental falls on level surfaces increased by 306%, and hospitalisations due to falls from stairs increased by 310%. Falls involving orthopaedic revision surgery (re-operation) are relatively rare, but the incidence has increased by approximately 35%. Hospital stays after falls on level surfaces involving re-operation were 1.0 day (median) longer and cost 50% (median) more than those that did not involve re-operation in 2005. After staircase falls, hospital stays for patients undergoing re-operations were 2.0 days (median) longer and cost 108% (median) more. The greater hospital costs and hospital stay for patients needing re-operations indicate that additional medical treatment was required.

  16. The Chernobyl – Thirty Years After The Post – Accidental Radiological – Hygienic and Medical Consequences

    Directory of Open Access Journals (Sweden)

    G. G. Onishchenko

    2016-01-01

    Full Text Available As the result of the Chernobyl NPP accident more than 200 thousand square kilometers of the European territories were contaminated by Cs-137 in the amount of above 37 kBq/m2 (1 Ci/km2 . Belorussia, Russia and Ukraine amount up to 70% of this entire affected area. More than 600 000 people were engaged in the accidental cleanup operations, 340000 were evacuated or relocated within 1986-1991. The early stage evacuation efficacy is confirmed by the absence of acute radiation syndrome among the population and by the prevented collective dose which amounts to no less than 10 000 man/Sv. The effective measure to reduce the internal radiation dose to the population at the early accidental stage was introduction of maximum tentative permissive levels of radionuclide content in the foodstuffs.Among the identified post -accident medical consequences of the Chernobyl is the radiation syndrome found in 134 emergency cleanup workers within the first 24 hours of the accident’s development. Out of that number, 28 people died within the first four months, 19 people died before 2006. The accident’s liquidators developed radiation -induced leukemia ( the attributive risk value is 45-60% . People exposed to high radiation doses display the statistically significant 18% morbidity increase of all types of solid cancers at the doses above 150 mSv. There is the statistically significant information indicating the increased amount of thyroid cancer morbidity among those who were just children and teenagers at the time of the accident. The adverse psychological consequences are accounted for not just the fear of overexposure but also for the disturbance of the habitual lifestyle especially mindful of the forced relocation.The longterm protection measures, radionuclide decay and selfcleaning of the contaminated areas resulted in the drastic reduction of the population dose in the radioactively contaminated territories. In 2015, only in some settlements of the Briansk

  17. Factores asociados a los accidentes por exposición percutánea en personal de enfermería en un hospital de tercer nivel

    Directory of Open Access Journals (Sweden)

    Gallardo López Mª Teresa

    1997-01-01

    Full Text Available FUNDAMENTO: Los accidentes por exposición percutánea suponen aproximadamente un tercio de los accidentes laborales del personal sanitario hospitalario. Su importancia estriba en las enfermedades causadas por patógenos transmisibles por esta vía (hepatitis B, hepatitis C, infección VIH. Objetivos: describir los accidentes de este tipo notificados en un hospital de tercer nivel; identificar factores asociados a estos accidentes en personal de enfermería; construir un modelo predictivo del riesgo individual de accidentarse. MÉTODOS: Estudio descriptivo de una cohorte retrospectiva compuesta por todas las personas que notificaron un accidente entre el 1-1-93 y el 30-6-96. Estudio de casos y controles en el personal de enfermería durante el período 1-1-95 al 30-6-96, analizado mediante regresión logística múltiple. RESULTADOS: La incidencia acumulada de accidentes en un año fue de 0,078 para las/-os enfermeras/-os. En el 57,3% de los casos estuvieron implicadas agujas de jeringas desechables o precargadas. La incidencia acumulada en un año fue mayor para las agujas de cateterismo intravenoso (8,5 por 100.000. El riesgo de accidentabilidad, ajustado por variables confundentes, fue mayor para las/-os enfermeras/-os (OR=3,22; I.C.95%=1,96-5,27, para los trabajadores de la Unidad de Hemodiálisis (OR=35,21; I.C.95%=3,74-331,16 y para aquéllos con contrato eventual (OR=4,50; I.C.95%=2,24-9,04. CONCLUSIONES: Los accidentes por exposición percutánea en este hospital son más frecuentes entre el personal de enfermería y se producen, fundamentalmente, con algún tipo de aguja hueca. Se han identificado factores asociados a estos accidentes, lo que permite dirigir programas preventivos específicos sobre trabajadores con más riesgo. El modelo obtenido es válido para estimar el grado de accidentabilidad individual en los sujetos estudiados.

  18. Urban Early Adolescent Narratives on Sexuality: Accidental and Intentional Influences of Family, Peers, and the Media.

    Science.gov (United States)

    Charmaraman, Linda; McKamey, Corinne

    2011-01-01

    In this paper, we examine the ways that early adolescents talked, interacted, and made references to events in their individual and collective lives during photography-based focus groups about sexuality and relationships. Twenty-three participants (10 boys and 13 girls) were recruited from three urban schools participating in a comprehensive sex education impact evaluation in the Northeast. We analyzed conversational narratives that were elicited in a group process while sharing photos of important people, contexts, and situations, showcasing participants' exploration of sexuality and relationships. Our analysis revealed four main themes: (a) direct and indirect family communication about sexuality, (b) accidental and intentional Internet usage, (c) shared and contested peer knowledge, and (d) school as a direct and indirect learning context. Implications and future directions for practice, research, and policy are explored.

  19. Tratamiento de Terapia Ocupacional en el accidente cerebrovascular

    Directory of Open Access Journals (Sweden)

    Domingo García, AM

    2006-02-01

    Full Text Available RESUMENEntre los muchos pacientes que necesitan tratamiento rehabilitador en Terapia Ocupacional están los que en la edad adulta han sufrido un accidente cerebrovascular.Uno de los factores de riesgo asociados con más frecuencia a las alteraciones del sistema nervioso central es el progresivo envejecimiento de la población, debido a esto orientaré el siguiente artículo hacia la intervención sobre la población geriátrica.La Terapia Ocupacional ofrece un tratamiento global que abarca las áreas funcional, motriz, sensorial, perceptivo y cognitiva. No debemos olvidar el asesoramiento realizado al paciente, a la familia y/ o cuidadores sobre el manejo de la persona que ha sufrido un ictus, la adaptación del entorno y la prescripción, uso y manejo de ayudas técnicas cuando sea necesario.Las propuestas terapéuticas que expondré a continuación, no son recetas únicas que se puedan emplear del mismo modo en todos las personas que hayan sufrido un ictus. Con cada paciente será necesario una evaluación individualizada de su situación y una adaptación de la terapia según sus déficit específicos.La meta final de la Terapia Ocupacional es la integración óptima del paciente dentro de su entorno familiar y social, con el mayor grado de autonomía posible.ABSTRACTAmong the patients who need Occupational Therapy’s rehabilitation treatment, there are those who have suffered a cerebrovascular damage when elderly.People’s gradual ageing is one of the risk factors in the nervous central system’s alterations and this is why I am going to write about intervention on geriatric population.The Occupational Therapy’s rehabilitation treatment works on the functional, motor, sensorial, perceptive and cognitive areas. Moreover, we should not forget to advise the patient and his/her family or caregivers about the way of treating ,the environment’s adaptation, the prescription and use of technical aids when needed.The following therapeutic

  20. Individualizing Services, Individualizing Responsibility

    DEFF Research Database (Denmark)

    Garsten, Christina; Hollertz, Katarina; Jacobsson, Kerstin

    -oriented, and the normative demands placed on individuals appear increasingly totalizing, concerning the whole individual rather than the job-related aspects only. The paper is based on 23 in-depth interviews with individual clients as well as individual caseworkers and other professionals engaged in client-related work...

  1. Numerical simulation of industrial and accidental release formation and transport

    Energy Technology Data Exchange (ETDEWEB)

    Piskunov, V.N.; Aloyan, A.A.; Gerasimov, V.M.; Pinaev, V.S.; Golubev, A.I.; Yanilkin, Yu.V.; Ivanov, N.V.; Nikonov, S.N.; Kharchenko, A.I. [and others

    1995-05-01

    Statement of work for contract 006 {open_quotes}Mathematical simulation of industrial and accidental release formation and transport{close_quotes} implies that the final result of the activity within this task will be VNIIEF developed techniques which will provide for the prediction of the post-accidental environment. Report [1] presents the description of physical models and calculation techniques which were chosen by VNIIEF to accomplish this task. These techniques were analysed for their capabilities, the areas of their application were defined, modifications within contract 006 were described, the results of test and methodical calculations were presented. Moreover, the experimental data were analysed over the source parameters and contamination measurements which can be used in the comparison with the calculation results. Based an these data this report compares the calculation results obtained with VNIIEF calculation techniques with the LANL-presented experimental results. The calculations which statements and results are given in section 1, included the following processes: explosion cloud ascent dynamics and jet release origin; aerosols kinetics in the release source including composite particle origin in the explosion cloud caused by radioactive substance sorption an the soil particles; contaminant transport in atmosphere and their in-site fallout due to the accidental explosions and fires; atmospheric flow dynamics and industrial contamination transfer over the complicated terrain. The calculated results were compared with the experimental data. Section 2 presents the parameters for a typical source in the explosion accidents based an the experimental results and calculated data from Section 1, as well as contamination patterns were calculated with basic technique {open_quotes}Prognosis{close_quotes}.

  2. Accidental Degeneracy and Berry Phase of Resonant States

    CERN Document Server

    Mondragón, A

    1997-01-01

    We study the complex geometric phase acquired by the resonant states of an open quantum system which evolves irreversibly in a slowly time dependent environment. In analogy with the case of bound states, the Berry phase factors of resonant states are holonomy group elements of a complex line bundle with structure group C*. In sharp contrast with bound states, accidental degeneracies of resonances produce a continuous closed line of singularities formally equivalent to a continuous distribution of "magnetic" charge on a "diabolical" circle, in consequence, we find different classes of topologically inequivalent non-trivial closed paths in parameter space.

  3. D-transallethrin: An unusual agent for accidental poisoning

    Directory of Open Access Journals (Sweden)

    Vinod Kedari

    2016-01-01

    Full Text Available D-trans allethrin, a pyrethroid, is commonly used as a coil mosquito repellant. There are very few reports of human toxicity due to D-trans allethrin. We present the case of an 11-month-old boy who presented to us with excessive salivation, altered sensorium and convulsions following alleged accidental ingestion of a coil containing D-transallethrin. He required mechanical ventilation for a brief period and made a full recovery. Although rare, the possibility of pyrethroid poisoning should be kept in mind in children who present with sudden onset unconsciousness or convulsions.

  4. ECMO for Cardiac Rescue after Accidental Intravenous Mepivacaine Application

    Directory of Open Access Journals (Sweden)

    Michael Froehle

    2012-01-01

    Full Text Available Mepivacaine is a potent local anaesthetic and used for infiltration and regional anaesthesia in adults and pediatric patients. Intoxications with mepivacaine affect mainly the CNS and the cardiovascular system. We present a case of accidental intravenous mepivacaine application and intoxication of an infant resulting in seizure, broad complex bradyarrhythmia, arterial hypotension and finally cardiac arrest. The patient could be rescued by prolonged resuscitations and a rapid initiation of ECMO and survived without neurological damage. The management strategies of this rare complication including promising other treatment options with lipid emulsions are discussed.

  5. Accidente Isquémico Transitorio: la gran oportunidad

    Directory of Open Access Journals (Sweden)

    Mª Dolores Fernández Couto

    2013-09-01

    Full Text Available El ictus constituye la primera causa de muerte en mujeres y la segunda causa de muerte global en España1, así como la primera causa de discapacidad adquirida en la edad adulta y la segunda causa de demencia por detrás de la enfermedad de Alzheimer. El accidente isquémico transitorio (AIT precede al ictus isquémico en un 23% de los casos2. Esta señal de alarma, lejos de poder considerarse banal, constituye una gran oportunidad para la prevención.

  6. Tratamiento de Terapia Ocupacional en el accidente cerebrovascular

    OpenAIRE

    Domingo García, AM

    2006-01-01

    RESUMENEntre los muchos pacientes que necesitan tratamiento rehabilitador en Terapia Ocupacional están los que en la edad adulta han sufrido un accidente cerebrovascular.Uno de los factores de riesgo asociados con más frecuencia a las alteraciones del sistema nervioso central es el progresivo envejecimiento de la población, debido a esto orientaré el siguiente artículo hacia la intervención sobre la población geriátrica.La Terapia Ocupacional ofrece un tratamiento global que abarca las áreas ...

  7. Clinical perspectives on osteogenesis imperfecta versus non-accidental injury.

    Science.gov (United States)

    Pereira, Elaine Maria

    2015-12-01

    Although non-accidental injuries (NAI) are more common in cases of unexplained fractures than rare disorders such as osteogenesis imperfecta (OI), ruling out OI and other medical causes of fracture is always indicated. The majority of OI patients can be diagnosed with the help of family history, physical examination, and radiographic findings. In particular, there are a few radiological findings which are seen more commonly in NAI than in OI which may help guide clinician considerations regarding the probability of either of these diagnoses. At the same time, molecular testing still merits careful consideration in cases with unexplained fractures without obvious additional signs of abuse.

  8. Measurement of accidental coincidences for higher activity sources

    CERN Document Server

    Yull Hwang, H; Jae-Oh, P; Man-Lee, J; Kie-Lee, M

    1999-01-01

    The multi-channel time-scaling (MCTS) technique has been applied for the measurement of accidental coincidences for the cases of higher activity samples in beta-gamma coincidence counting. Two beta samples of sup 1 sup 3 sup 4 Cs were prepared and the nominal activities observed in the beta counter were about 7000 and 11000 s sup - sup 1 , respectively. The obtained true coincidence rates are independent of resolving times and dead times. They are compared with those calculated from the mathematical model derived by Cox and Isham.

  9. Accidentes de trabajo en un hospital de agudos

    Directory of Open Access Journals (Sweden)

    Pérez Bermúdez B.

    1998-01-01

    Full Text Available FUNDAMENTO: El mejor conocimiento de los determinantes y circunstancias de producción de los accidentes laborales, favorecerá la implantación de medidas correctoras. El objetivo de este trabajo es describir la evolución temporal de los accidentes de trabajo (AT y determinar los factores de riesgo de baja médica en el Hospital Dr. Peset de Valencia. MÉTODOS: Descripción y análisis retrospectivo de los accidentes de trabajo producidos en el Hospital Dr. Peset de Valencia durante los años 1992 a 1995. Se estimó por métodos deterministas la tendencia y estacionalidad de las series (índices estacionales, IE. Se aplicó un modelo de regresión logística para identificar los factores pronósticos de baja médica y determinar su probabilidad de ocurrencia . RESULTADOS: Las tasas más elevadas de AT se produjeron entre los trabajadores de cocina y lavandería (10,00 AT por 100 trabajadores-año. Los AT con baja médica mantienen una tendencia cercana a cero siendo febrero el mes con I.E más elevado (IE=139,8. Los que cursan sin baja médica tienen una tendencia positiva (r²=0,23, p<0,0001, siendo mayo el mes de mayor siniestralidad (IE=134,2. La probabilidad de que el accidente curse con baja médica aumenta significativamente con la edad, cuando se produce por la tarde, si ha tenido lugar en cocina/lavandería, y si se trata de un esguince o tendinitis. CONCLUSIONES: la actuación sobre la siniestralidad en los AT que cursen con IT, debería centrarse sobre los trabajos menos cualificados y en las áreas de cocina y lavandería.

  10. Costes e Investigación de Accidentes Laborales

    OpenAIRE

    Gonzalez Quintana, Jon Ander

    2013-01-01

    En España en el año 2011, según datos del Instituto Nacional de Estadística (INE), se registraron 581.150 accidentes con baja laboral de los cuales el 88% sucedieron dentro de jornada laboral. Observando estas cifras, es obvio que hay una carencia en el sistema preventivo y, por los tanto, es necesario buscar una solución. Son tres los factores de la baja inversión en prevención: la falta de concienciación de las empresas, la falta del conocimiento de las consecuencias de un...

  11. Accidental Chemical Burns of Oral Mucosa by Herbicide

    Directory of Open Access Journals (Sweden)

    S P Deo

    2012-03-01

    Full Text Available Glyphosate (GlySH is a broad spectrum, nonselective herbicide, widely used in agriculture. This case report describes a 25-year-old man presenting with extensive chemical burns and ulceration of the oral cavity as a result of accidental exposure to GlySH. This paper aims to illustrate the typical appearance of GlySH related chemical mucosal burn and to demonstrate the severity of the corrosive effect of GlySH which need team approach to prevent unfavorable sequelae such as microstomia. Keywords: Chemical burns, corrosive injury, glyphosate poisoning, herbicide, microstomia, oral mucosal burn.

  12. Multidisciplinary approach to "accidental" falls in the elderly: a case report.

    Science.gov (United States)

    Galizia, Gianluigi; Testa, Gianluca; Mazzella, Francesca; Cacciatore, Francesco; Ungar, Andrea; Masotti, Giulio; Rengo, Franco; Abete, Pasquale

    2008-06-01

    Falls in the elderly are commonly and often wrongly identified as "accidental". We report a case of an elderly woman admitted to first aid for a trauma due to an accidental fall. Geriatric multidisciplinary evaluation revealed mild cognitive impairment associated with depressive symptoms; both findings made the anamnesis uncertain. Syncope algorithm was applied and "tachy-brady form of sick sinus syndrome" was diagnosed. Differential diagnosis between "accidental" and "apparently accidental" falls in elderly patients is very difficult but a multidisciplinary geriatric evaluation can clarify the correct diagnosis.

  13. Urban "accidental" wetlands mediate water quality and heat exposure for homeless populations in a desert city

    Science.gov (United States)

    Palta, M.

    2015-12-01

    In urban settings where humans interact in complex ways with ecosystems, there may be hidden or unanticipated benefits (services) or harm (disservices) conferred by the built environment. We examined interactions of a highly vulnerable population, the homeless, with urban waterways and wetlands in the desert city of Phoenix, Arizona, U.S.A. Climate change models project increases in heat, droughts, and extreme floods for the southwestern U.S. These projected changes pose a number of problems for sustainability and quality of future water supply, and the ability of human populations to mitigate heat stress and avoid fatalities. Urban wetlands that are created "accidentally" (by water pooling in abandoned areas of the landscape) have many structural (e.g., soils and hydrology) and functional (e.g., high denitrification) elements that mimic natural, unaltered aquatic systems. Accidental wetland systems in the dry bed of the Salt River, fed by storm and waste water from urban Phoenix, are located within economically depressed sections of the city, and show the potential for pollutant and heat mitigation. We used a mixed-method socio-ecological approach to examine wetland ecosystem functions and the ways in which homeless populations utilize Salt River wetlands for ecosystem services. Interviews and trash surveys indicated that homeless people are accessing and utilizing the wetlands as a source of running water, for sanitary and heat mitigation services, and for recreation and habitation. Environmental monitoring demonstrated that the wetlands can provide a reliable source of running water, nutrient and pathogen removal, heat mitigation, and privacy, but they may also pose a health risk to individuals coming in contact with the water through drinking or bathing. Whether wetlands provided a net benefit vs. harm varied according to site, season, and particular service, and several tradeoffs were identified. For example, heat is highest during the summer storm season

  14. Pathological Findings in Accidental Electrocution in a Horse (Case Report

    Directory of Open Access Journals (Sweden)

    Adrian Florin Gal

    2016-11-01

    Full Text Available Recently, the veterinarians are dealing with a number of cases that require forensic expertise. Such a circumstance could be the accidental electrocution in animals, one of the causes of unnatural death. There is a scarcity with reference to the pathological findings in veterinary forensic medicine. In this paper, we present the main lesions that occurred in a horse with accidental electrocution that was presented for complete necropsy survey. A horse corpse was sent to the Pathology Department (Faculty of Veterinary Medicine, Cluj-Napoca, Romania for a full medical survey. Preliminary results and external examination: the body was in rigor mortis; from the nasal cavities drained out reddish foam and in the mouth was observed the presence of ingested feed (straw that was not chewed, suggesting a quick death. The findings detected after internal examination of the carcass were poor blood coagulability, haemorrhagic diathesis throughout the body, with haemorrhages of various sizes in different body regions (e.g., muscles of the withers, in the gluteal muscle, the mucosa of epiglottis, larynx, trachea, in the interstitium of the lung, and ecchymosis in the left kidney. Some other lesions detected were infarcts and haemorrhages in the fundic region of the stomach’s mucosa. In electrocution, haemorrhages are most often located in the respiratory tract, aspect observed in our case too. However, the diagnosis of electrocution has to corroborate the necropsy findings (which are not specific, with some other data such as the fulminant death and inspection of power source.

  15. Accidental childhood death and the role of the pathologist.

    Science.gov (United States)

    Byard, R W

    2000-01-01

    The following study provides an overview of accidental childhood death. This study is based on a review of 369 cases of fatal childhood accidents taken from the records of the Department of Histopathology, Women's and Children's Hospital, Adelaide, Australia, over a 34-year period from 1963 to 1996. Data provide information on deaths due to motor vehicle accidents, drownings, accidental asphyxia, burns, poisonings, electrocution, and miscellaneous trauma. In addition, certain categories have undergone further examination, including asphyxial deaths due to unsafe sleeping environments and unsafe eating practices, drowning deaths, and deaths on farms, following identification of significant child safety problems in these areas as part of the "Keeping Your Baby and Child Safe" program. Previously unrecognized dangers to children detected through this program include mesh-sided cots, V-shaped pillows, and certain types of stroller-prams. The production of information pamphlets and packages for parents and the recall of certain dangerous products following recommendations made by pathologists demonstrate that pediatric and forensic pathologists have an important role to play in preventive medicine issues and in formulating public health strategies.

  16. accidentes y otras causas violentas en la sierra de Sonora

    Directory of Open Access Journals (Sweden)

    Héctor Eloy Rivas Sánchez

    2005-01-01

    Full Text Available Este artículo presenta los resultados de una investigación sociológica cuyo objeto fue explorar el papel que ha jugado el modelo hegemónico de masculinidad en la ocurrencia de muertes derivadas de accidentes y varias formas de ejercicio de la violencia en una comunidad rural de la sierra de Sonora. Estos resultados difieren de aquellos que tradicionalmente los estudios de las masculinidades han mostrado para México y América Latina. El modelo dominante de masculinidad en las comunidades estudiadas no ha condicionado significativamente la ocurrencia de las muertes por accidentes y otras causas violentas. La responsabilidad, la disciplina y el respeto hacia las personas consideradas socialmente débiles (mujeres, ancianos y niños, principalmente son características que debe poseer un hombre de verdad en las comunidades estudiadas. El apego de los hombres a estas formas de comportamiento y su temor a perder honorabilidad como hombre de verdad si se desvían de estas normas de conducta los ha llevado a evitar una serie de prácticas temerarias que pudieron poner en riesgo su vida y la de otras personas.

  17. Circumstances and factors associated with accidental deaths among children, adolescents and young adults in Cuiaba, Brazil

    Directory of Open Access Journals (Sweden)

    Christine Baccarat de Godoy Martins

    Full Text Available CONTEXT AND OBJECTIVE Analysis on accidents from the perspective of population segments shows there is higher incidence among children, adolescents and young adults. Since the characteristics and circunstances of the event are closely related to educational, economic, social and cultural issues, identifying them may contribute towards minimizing the causes, which are often fatal. The aim here was to identify the environmental, chemical, biological and cultural factors associated with deaths due to accidents among children, adolescents and young adults in Cuiabá, in 2009. DESIGN AND SETTING This was a descriptive cross-sectional study conducted in Cuiabá, Mato Grosso, Brazil. RESULTS Thirty-nine accidental deaths of individuals aged 0 to 24 years were examined: 56.4% due to traffic accidents; 25.6%, drowning; 10.3%, aspiration of milk; 5.1%, falls; and 2.6%, accidentally triggering a firearm. Male victims predominated (82.1%. The presence of chemical, environmental and biological risk factors was observed in almost all of the homes. Regarding cultural factors and habits, a large proportion of the families had no idea whether accidents were foreseeable events and others did not believe that the family's habits might favor their occurrence. Delegation of household chores or care of younger siblings to children under the age of 10 was common among the families studied. CONCLUSION The results point towards the need to have safe and healthy behavioral patterns and environments, and to monitor occurrences of accidents, thereby structuring and consolidating the attendance provided for victims.

  18. Amputación corporal por accidente de trabajo en auxiliar de enfermería

    Directory of Open Access Journals (Sweden)

    Alexander Finol Muñoz

    2014-12-01

    Full Text Available Los auxiliares de enfermería son un rango profesional expuesto a múltiples riesgos por las actividades inherentes a su trabajo, expuestos constantemente a sustancias desinfectantes que sin el uso apropiado de equipos de protección individual, puede provocar efectos adversos y lesiones en el trabajador. Caso Clínico: Mujer de 51 años de edad, auxiliar de enfermería, con antecedentes de Diabetes Mellitus tipo I y Síndrome de Túnel Carpiano. Presenta derrame accidental de líquido mientras llenaba envase de Biguanid®, cayéndole en todo el cuerpo, por lo que decide cambiarse el uniforme entero, conservando calcetines y zapatos por el resto del turno. Posteriormente presenta lesiones en región dorsal de 4tº dedo de pie izquierdo, las cuales reciben tratamiento médico y seguimiento, con evolución tórpida, se evidencia edema y osteomielitis de la falange por lo que se decide amputar el dedo afectado. Una vez recuperada, fue estudiada con pruebas de provocación, evidenciando la susceptibilidad de la trabajadora a dicho desinfectante. Se propone al Instituto Nacional de Seguridad Social (INSS como accidente de trabajo y una indemnización por lesión permanente no invalidante, ambas peticiones con respuesta favorable para la trabajadora. Actualmente sigue desempeñando sus funciones como auxiliar en el hospital. El cumplimiento y vigilancia de las normas de prevención, basados en los riesgos laborales permitirá evitar este tipo de incidentes en la población laboral, evitando a largo plazo lesiones corporales, discapacidades y bajas laborales que alteran la calidad de vida del trabajador y de su entorno profesional.

  19. Accidental bilateral Q-switched neodymium laser exposure: treatment and recovery of visual function

    Science.gov (United States)

    Zwick, Harry; Stuck, Bruce E.; Dunlap, Weldon; Scales, David K.; Lund, David J.; Ness, James W.

    1998-05-01

    A 21 year old female was accidentally exposed in both eyes when she looked into the 10 cm exit aperture of a military laser designator emitting 1064 nm q-switched (30 ns) pulses at a 10 pulse per second rate. Steroid therapy (methylprednisolone sodium succinate) was initiated within 6 hours post exposure. Initial ophthalmoscopic observation revealed small contained macular hemorrhages in each eye. Fluorescein angiography (FA) showed minimal leakage. Visual acuity was 20/100 and 20/60 in OD and OS respectively. Contrast sensitivity in both eyes was depressed across all spatial frequencies by more than 1.5 log units. At four weeks post exposure, no significant macular scarring was apparent and visual acuity returned to 20/25 in both eyes. Contrast sensitivity had improved to normal levels with a peak at 3 cycles/degree. At one year post exposure, visual acuity was 20/13 in both eyes and measures of contrast sensitivity were within normal limits. During the course of recovery, the patient's fixation shifted from a slightly superior temporal site back to the central foveal region. The foveal lesion sites were still evident by ophthalmoscopy and Amsler grid measurements but were deemed functional when the patient placed small targets generated by the scanning laser ophthalmoscope in the lesion site for discrimination. This outcome indicates remarkable recovery of visual function and suggests that early administration of steroids may assist in preserving the natural neural recovery process of the photoreceptor matrix by minimizing intraretinal scar formation.

  20. [Accidental intravenous injection of potassium chloride: analysis of contributing factors and barriers to risk reduction].

    Science.gov (United States)

    Bonvin, A; Vantard, N; Charpiat, B; Pral, N; Leboucher, G; Philip-Girard, F; Viale, J-P

    2009-05-01

    Errors linked to injectable potassium chloride (KCl) have been the cause of deaths which have occurred for many years. Following an accidental direct intravenous injection of KCl of no clinical consequence for the patient, we have analyzed the contributive factors, established an action plan to prevent this risk and finally assessed its impact. Among the causes leading to medication errors, we have identified those linked to the handling of the drugs by nurses, the team, the work conditions, the organization, the institutional context and finally to the drug itself. The risk reduction procedure involved a withdrawal of injectable KCI ampoules from wards, possible in 52% of the care units, a reorganization of storage for the others. The subsequent monitoring of floorstocks revealed that these measures were insufficient and that the risks prevailed due to the presence of KCI ampoules in drawers assigned to other ionic solutions. A study carried out among the medical and nursing personnel revealed that 61.2% of the doctors thought that the risk existed in their ward and 68% of the nurses considered themselves to be exposed to the risk of a medication error. The drug supply chain of our institution, as in numerous others, is not safe. Hospitals are not yet organized adequately to prevent the occurrence of such an error. The comparison with foreign organizations of drug dispensation allows us to think that the improvement and professionalization of the drug supply chain will both be assets in the prevention of such medication errors.

  1. Accidental nuclear excursion recuplex operation 234-5 facility: Final medical report

    Energy Technology Data Exchange (ETDEWEB)

    Fuqua, P. A.

    1962-04-07

    The April 7, 1962 criticality accident involving human exposures was the first to have occurred in any production facility at Hanford. The accidental nuclear excursion did not result in any mechanical damage or spread of contamination. Three employees received over-exposure to gamma and neutron radiation. None were fatally exposed and in each case the over-exposure was recognized promptly. Following an initial period of medical observation and testing, the men were released to work. They continued to be followed clinically. Clinical studies performed were hematological procedures including leukocyte chromosome aberrations, morphologically aberrant blood cells, bone marrow evaluations, blood chemistry determinations, amino acid excretion studies, seminal fluid, urinary gonadotropins and estrogen excretion studies, testicular biopsies and crystalline lens examinations. These studies, along with a brief description of the accident and of the dosimetry, are summarized in this report by those participating in the studies. In view of the dose ranges received in these cases, both the negative and positive findings are considered to be of unusual interest due to the lack of knowledge of effects following human exposures at these levels.

  2. [Accidental hypothermia in adults: taking charge by the SAMU of Paris].

    Science.gov (United States)

    Deny, N; Bresard, D; Bertrand, J; Poisvert, M

    1990-02-01

    Thirty one cases of accidental hypothermia have been taken in care by the SAMU de Paris during the year of 1987. The accidental hypothermias happening in the cities are, most of the time, moderated and not very serious. The search for a cause is a prime necessity. The prognosis is based on that search to guide and advise the patients.

  3. Accidental Perforation of Endotracheal Tube during Orthognathic Surgery for Maxillary Prognathism - a Case Report

    Directory of Open Access Journals (Sweden)

    Manish Jain

    2008-01-01

    Full Text Available Maxillary prognathism(excess is a congenital anomaly characterized by facial disfigurement. Accidental perforation of endotracheal tube during corrective surgery is not an uncommon complication. A case of accidental perforation of endotracheal tube during surgery and its management is presented here.

  4. A novel method to detect accidental oesophageal intubation based on ventilation pressure waveforms

    NARCIS (Netherlands)

    Kalmar, Alain F.; Absalom, Anthony; Monsieurs, Koenraad G.

    2012-01-01

    Background: Emergency endotracheal intubation results in accidental oesophageal intubation in up to 17% of patients. This is frequently undetected thereby adding to the morbidity and mortality. No current method to detect accidental oesophageal intubation in an emergency setting is both highly sensi

  5. Two Cases of Accidental Injection of Epinephrine into a Digit Treated with Subcutaneous Phentolamine Injections

    Directory of Open Access Journals (Sweden)

    Ryan P. Bodkin

    2013-01-01

    Full Text Available Accidental injection into the digit from an epinephrine autoinjection device can cause discoloration, pain, and paresthesias. Although loss of digit is rare, treatment in the emergency department is commonly aimed at vasodilation of the affected tissue. We report two cases of accidental injection of epinephrine into the digits that were successfully treated with subcutaneous phentolamine injection with no adverse events.

  6. 76 FR 73021 - Agency Information Collection (Report of Accidental Injury in Support of Claim for Compensation...

    Science.gov (United States)

    2011-11-28

    ... Injury in Support of Claim for Compensation or Pension/Statement of Witness to Accident, VA Form 21- 4176...: VA Form 21-4176 is used to support a claim for disability benefits based on an accidental injury that... AFFAIRS Agency Information Collection (Report of Accidental Injury in Support of Claim for Compensation...

  7. Accidental intraoral formalin injection: a rare case report

    Directory of Open Access Journals (Sweden)

    Ramakant Dandriyal

    2014-12-01

    Full Text Available Formalin is a hazardous chemical that needs cautious handling and special storage. Owing to its disinfectant and fixative (i.e. for preserving pathologic tissue specimens in histopathology properties, it is widely used in dentistry. Although, the terms formaldehyde and formalin are often confused as being identical, these are different as to the concentrations of the primary component i.e. formaldehyde. In fact, the common fixative available as 10% neutral buffered formalin is actually a 4% solution of formaldehyde (i.e., a 10% solution made from a 37-40% commercially pure formaldehyde solution. This case report describes an unfortunate case of accidental injection instead of local anesthetic, of formalin into the pterygomandibular space in a 35-year old woman during inferior alveolar nerve block for surgical removal of impacted lower right third molar and its successful management by cautious debridement (under both local and general anesthesia and empirical drug therapy (utilizing analgesics and antibiotics.

  8. Accidental intraoral formalin injection: a rare case report.

    Science.gov (United States)

    Dandriyal, Ramakant; Giri, Kolly Yada; Alam, Sarwar; Singh, Aishwarya Pratap

    2014-10-30

    Formalin is a hazardous chemical that needs cautious handling and special storage. Owing to its disinfectant and fixative (i.e. for preserving pathologic tissue specimens in histopathology) properties, it is widely used in dentistry. Although, the terms formaldehyde and formalin are often confused as being identical, these are different as to the concentrations of the primary component i.e. formaldehyde. In fact, the common fixative available as 10% neutral buffered formalin is actually a 4% solution of formaldehyde (i.e., a 10% solution made from a 37-40% commercially pure formaldehyde solution). This case report describes an unfortunate case of accidental injection instead of local anesthetic, of formalin into the pterygomandibular space in a 35-year old woman during inferior alveolar nerve block for surgical removal of impacted lower right third molar and its successful management by cautious debridement (under both local and general anesthesia) and empirical drug therapy (utilizing analgesics and antibiotics).

  9. Accidental endoscopic finding of Anisakis simplex in human colon

    Directory of Open Access Journals (Sweden)

    Aurelia Aloia

    2011-09-01

    Full Text Available Anisakidosis is a zoonotic disease caused by the ingestion of nematodes belonging to the family of Anisakidae. Human infection is caused by intake of raw or undercooked sea fish and cephalopods infested by Anisakis larvae. We present a case of accidental endoscopic finding of an alive nematode adhering to distal ascending colon in a 32 years old man, submitted to colonoscopy owing to recent onsets of rectal bleeding of likely hemorrhoidal origin. The nematode, removed from colon by means of biopsy forceps, has been identified as L3 larvae of A. simplex by a light microscope. Histological examination of intestinal mucosa showed a mild fibrosis of lamina propria, characterized by focal lymphocytic inflammation and scattered infiltration of eosinophils. The patient reported the intake of marinated anchovies 3 days before endoscopic examination.

  10. Application of biological dosimetry in accidental radiation exposure

    Energy Technology Data Exchange (ETDEWEB)

    Nosal, M.; Batora, I.; Kolesar, D.; Stojkovic, J. (Komenskeho Univ., Bratislava (Czechoslovakia). Lekarska Fakulta); Gaal, P.; Sklovsky, A. (Krajska Hygienicka Stanica, Bratislava (Czechoslovakia)); Cizova, O. (Sexuologicka Ambulancia KUNZ, Bratislava (Czechoslovakia))

    1982-03-01

    The case is described of accidental irradiation of a male person with /sup 137/Cs of an activity of 24.71 GBq. The first estimate induced a reasonable suspicion that the absorbed dose could be very high and life-threatening. On the other hand the clinical picture, usual laboratory examinations, findings in the fluorescent blood count, the analysis of chromosomal count of lymphocytes in the peripheral blood, the spermiogram, and the negative post-irradiation porphyrinuria suggested that the absorbed dose could be much lower than the original estimate. The results of dosimetry obtained after the reconstruction of the accident by measuring on a phantom revealed that the actual dose was very close to that presumed from the results of biological dosimetry during the first days of examination of the patient.

  11. Siquieros accidental painting technique: a fluid mechanics point of view

    CERN Document Server

    Zetina, Sandra

    2012-01-01

    This is an entry for the Gallery of Fluid Motion of the 65th Annual Meeting of the APS-DFD (fluid dynamics video). This video shows an analysis of the 'accidental painting' technique developed by D.A. Siqueiros, a famous Mexican muralist. We reproduced the technique that he used: pouring layers of paint of different colors on top of each other. We found that the layers mix, creating aesthetically pleasing patterns, as a result of a Rayleigh-Taylor instability. Due to the pigments used to give paints their color, they can have different densities. When poured on top of each other, if the top layer is denser than the lower one, the viscous gravity current undergoes unstable as it spread radially. We photograph the process and produced slowed-down video to visualize the process.

  12. Subtraction of "accidentals" and the validity of Bell tests

    CERN Document Server

    Thompson, C H

    1999-01-01

    In some key Bell experiments, including two of the well-known ones by Alain Aspect, 1981-2, it is only after the subtraction of ``accidentals'' from the coincidence counts that we get violations of Bell tests. The data adjustment, producing increases of up to 60% in the test statistics, has never been adequately justified. Few published experiments give sufficient information for the reader to make a fair assessment. There is a straightforward and well known realist model that fits the unadjusted data very well. In this paper, the logic of this realist model and the reasoning used by experimenters in justification of the data adjustment are discussed. It is concluded that the evidence from all Bell experiments is in urgent need of re-assessment, in the light of all the known ``loopholes''. Invalid Bell tests have frequently been used, neglecting an improved one derived by Clauser and Horne in 1974. ``Local causal'' explanations for the observations have been wrongfully neglected.

  13. FACTORES DE RIESGO QUE OCASIONAN ACCIDENTES LABORALES EN EL PERSONAL DE ENFERMERÍA DE UNA CLÍNICA ACREDITADA DE LA CIUDAD DE AREQUIPA, 2007-2008

    OpenAIRE

    GARCIA SUTTA, PATRICIA CONCEPCION

    2014-01-01

    FACTORES DE RIESGO CONCEPTUALIZACIÓN TIPOS RIESGOS NO MECÁNICOS RUIDOS RADIACIONES IONIZANTES ILUMINACIÓN CALOR FRÍO RIESGOS FÍSICOS MECÁNICOS RIESGOS QUÍMICOS RIESGOS ERGONÓMICOS POSTURA RIESGOS BIOLÓGICOS CARGA DE TRABAJO LABORAL DEFINICIÓN ACCIDENTES LABORALES ACCIDENTE CAUSAS BÁSICAS Y CAUSAS INMEDIATAS ACCIDENTES LABORALES CAUSAS DE LOS ACCIDENTES TIPOS DE ACCIDENTE TIPOS DE ACCIDENTES LABORALES

  14. A national survey (NAP5-Ireland baseline) to estimate an annual incidence of accidental awareness during general anaesthesia in Ireland.

    LENUS (Irish Health Repository)

    Jonker, W R

    2014-06-29

    As part of the 5th National Audit Project of the Royal College of Anaesthetists and the Association of Anaesthetists of Great Britain and Ireland concerning accidental awareness during general anaesthesia, we issued a questionnaire to every consultant anaesthetist in each of 46 public hospitals in Ireland, represented by 41 local co-ordinators. The survey ascertained the number of new cases of accidental awareness becoming known to them for patients under their care or supervision for a calendar year, as well as their career experience. Consultants from all hospitals responded, with an individual response rate of 87% (299 anaesthetists). There were eight new cases of accidental awareness that became known to consultants in 2011; an estimated incidence of 1:23 366. Two out of the eight cases (25%) occurred at or after induction of anaesthesia, but before surgery; four cases (50%) occurred during surgery; and two cases (25%) occurred after surgery was complete, but before full emergence. Four cases were associated with pain or distress (50%), one after an experience at induction and three after experiences during surgery. There were no formal complaints or legal actions that arose in 2011 related to awareness. Depth of anaesthesia monitoring was reported to be available in 33 (80%) departments, and was used by 184 consultants (62%), 18 (6%) routinely. None of the 46 hospitals had a policy to prevent or manage awareness. Similar to the results of a larger survey in the UK, the disparity between the incidence of awareness as known to anaesthetists and that reported in trials warrants explanation. Compared with UK practice, there appears to be greater use of depth of anaesthesia monitoring in Ireland, although this is still infrequent.

  15. The effect of a non-steroidal anti-inflammatory drug on two important predictors for accidental falls: postural balance and manual reaction time. A randomized, controlled pilot study.

    NARCIS (Netherlands)

    Hegeman, J.; Nienhuis, B.; Bemt, B.J.F van den; Weerdesteijn, V.G.M.; Limbeek, J. van; Duysens, J.E.J.

    2011-01-01

    Accidental falls in older individuals are a major health and research topic. Increased reaction time and impaired postural balance have been determined as reliable predictors for those at risk of falling and are important functions of the central nervous system (CNS). An essential risk factor for fa

  16. Suicidio disimulado como accidente de tráfico: A propósito de un caso Suicide masquerading as traffic accident: case report

    Directory of Open Access Journals (Sweden)

    ME. Domínguez Pedroso

    2007-10-01

    Full Text Available Los motivos que inducen a una persona a enmascarar un suicidio simulando una muerte accidental pueden ser varios. Exponemos un caso en el que la víctima utiliza un accidente de tráfico para disimular un suicidio por arma de fuego y de esta forma conseguir que fuesen abonadas tanto la indemnización del Seguro de Automóviles como los incluidos en un seguro privado contratado poco antes. Sólo a través de una adecuada investigación del lugar de los hechos y de los antecedentes de la víctima junto a la realización del indispensable estudio necrópsico será posible determinar la verdadera etiología médico-legal de las muertes en accidente de tráfico, con especial atención en las que interviene sólo un vehículo con un único ocupante.There are several reasons that induce somebody to mask a suicide simulating an accidental death. We expose a case in which the victim uses a traffic accident to masquerade a suicide by shotgun. By this way, the author tries to receive the reimbursement of the car’s insurance as well as the money included in a private life insurance contracted just few days before. Only with the careful local death examination and the study of the victim's personal history, plus the essential autopsy, could we manage to understand the real aetiology of deaths in traffic accidents, especially focusing on those cases where there is a single car with a single passenger affected.

  17. Accidental Children Poisoning With Methadone: An Iranian Pediatric Sectional Study

    Directory of Open Access Journals (Sweden)

    Sayena JABBEHDARI

    2013-11-01

    Full Text Available How to Cite This Article: Jabbehdari S, Farnaghi F, Shariatmadari SF, Jafari J, Mehregan FF, Karimzadeh P. Accidental Children Poisoning With Methadone: An Iranian Pediatric Sectional Study. Iran J Child Neurol. 2013 Autumn;7(7: 32-34.ObjectiveToxic poisoning with methadone is common in children in Iran. Our study was carried out due to the changing pattern of methadone poisoning in recent years and increasing methadone toxicity. Materials & MethodsIn this descriptive-sectional study, all of the methadone poisoned children younger than 12 years who were admitted to the Loghman Hakim Hospital in 2012, were assessed. Clinical symptoms and signs, para-clinical findings, and treatment were evaluated. ResultsIn this study, 16 boys and 15 girls who had been poisoned by methadone were enrolled. The mean age of patients was 55 months. All patients had been poisoned randomly or due to parent’s mistakes. The mean time of symptoms onset after methadone consumption was 1 hour and 30 Min, indicating a relatively long time after onset of symptoms.Clinical findings were drowsiness (75%, miotic pupil (68 %, vomiting (61%, rapid shallow breathing (57% and apnea (40%. In paraclinical tests, respiratory acidosis (69% and leukocytosis (55.2% were seen. The most important finding was increase in distance of QT in ECG (23.8%. The mean time of treatment with naloxone infusion was 51 hours. Three percent of patients had a return of symptoms after discontinuation of methadone. In patients with apnea, a longer course of treatment was required, and this difference was significant. Also, 17% of patients with apnea had aspiration pneumonia, which was statistically significant. ConclusionWe suggest long time treatment with naloxone and considering the probability of return of symptoms after discontinuation of methadone.ReferencesGoldfrank L, Flomenbaum N, Lewin N. Goldfrank’s Toxicologic Emergencies. 7th ed. McGraw–Hill 2002; p. 590-607.Schelble DT. Phosgene and

  18. The Frequency of the Accidental Contamination with Laboratory Samples in Yazd Clinical Laboratories’ personnel in 2011

    Directory of Open Access Journals (Sweden)

    Jafari, AA. (PhD

    2014-05-01

    Full Text Available Background and Objective: laboratory personnel have always accidental exposure to clinical samples, which can cause the transmission of infection. This threat can be prevented and controlled by education for the use of safety instruments. The purpose was to determine the frequency of accidental exposure to laboratory samples among Yazd laboratory personnel in 2011. Material and Methods: This descriptive cross-sectional study was conducted on 100 of Yazd clinical laboratory personnel. The data was collected, using a valid and reliable questioner, via interview and analyzed by means of SPSS software. Results: Eighty-six percent of the subjects reported an experience of accidental exposure to clinical samples, such as blood, serum and urine. The causes were carelessness (41% and work overload (29%. Needle- stick was the most prevalent injury (52% particularly in sampler workers (51% and in their hands (69%. There wasn’t significant relationship between accidental exposure to laboratory samples and the variables such as private and governmental laboratories (p=0.517, kind of employment (p=0.411, record of services (p=0.439 and academic degree (p=0.454. The subjects aged 20-29 (p=0.034 and worked in sampling unit had the highest accidental exposure. Conclusion: based on the results, inexperience of the personnel especially in sampling room, overload at work and ignorance of applying safety instruments are known as the most important reasons for accidental exposure to clinical samples. Keywords: Contamination; accidental Exposure; Infectious agents; laboratory; personnel

  19. Calidad de vida de cuidadores de adultos con accidente cerebrovascular

    Directory of Open Access Journals (Sweden)

    INNA ELIDA FLÓREZ TORRES

    2010-10-01

    Full Text Available Objetivo: describir la calidad de vida de los cuidadores familiares de adultos con secuelas de accidente cerebrovascular, en Cartagena, Colombia. Método: estudio descriptivo cuantitativo realizado durante el segundo semestre de 2008. Muestra no probabilística por conveniencia de 97 cuidadores. Se empleó el instrumento propuesto por Ferrell et ál. Para valorar cada uno de los bienestares que integran la calidad de vida se utilizaron medidas de tendencia central y coeficiente de variación. Resultados: el grupo de cuidadores presentó en el bienestar físico un promedio de 11,1 con relación al máximo puntaje, lo que indica el peor estado de salud; los bienestares psicológico y social tuvieron promedios de 48,8 y 21,9, respectivamente, con menor afectación. El mejor estado se halló en el bienestar espiritual, con promedio de 22,6. Conclusiones: la experiencia de ser cuidador modifica de manera importante la calidad de vida de las personas; los cuidadores, como fuente importante de cuidado informal, requieren apoyo de los sistemas de salud y, como parte de este, de los profesionales de enfermería.

  20. [Gonococcal vulvovaginitis in prepubertal girls: sexual abuse or accidental transmission?].

    Science.gov (United States)

    Daval-Cote, M; Liberas, S; Tristan, A; Vandenesch, F; Gillet, Y

    2013-01-01

    Vulvovaginitis is the most frequent gynecologic pathology among prepubertal females. An infectious cause is found in 30% of cases and is highly associated with the presence of vaginal discharge upon examination. Neisseria gonorrhoeae may be one of the causative agents. Since N. gonorrhoeae is a common sexually transmitted disease, sexual abuse should be considered in the pediatric setting. We report the case of a 5-year-old girl with N. gonorrhoeae vulvovaginitis. Her previous history, multiple interviews with the patient and her parents, and clinical examination showed no evidence or signs of sexual abuse. Both parents presented gonorrhea, urethritis for the father and vaginitis for the mother. The discrepancy between pediatric evaluation and the presence of a bacterium associated with sexually transmitted disease led us to consider other means of contamination. Previous studies have shown that other routes of transmission are possible but are often neglected. Hence, contamination can be transmitted by the hands or mostly through passive means (towels, rectal thermometer, etc.). Many epidemics have been noted in group settings with young girls with no evidence of sexual transmission. Therefore, we concluded that this patient's infection was likely an accidental transmission within her family. The acknowledgement of these transmission routes is very important in order to avoid misguided suspicion of sexual abuse and the possible traumatic family and psychosocial consequences.

  1. High mortality due to accidental salinomycin intoxication in sheep

    Directory of Open Access Journals (Sweden)

    Ashrafihelan Javad

    2014-09-01

    Full Text Available In February 2012, 100% mortality was reported in a herd with 79 local sheep that were kept around of Abhar, Northwest of Iran. The ration for adult sheep was daily mixed (40 kg straw, 25 kg wheat and 2 kg Vit-C premix and accidentally 1 500 g of salinomycin (Salinomycin 12% Premix; Aras Bazar Laboratories, Iran had been added to the ration (22388 mg/kg = 22388 ppm and overnight was fed to herd. At the morning, 78 sheep were founded dead and one of them showed convulsive seizures. Postmortem examination revealed pulmonary congestion and edema, hemorrhages in abomasum, large pale kidney and white streak lines in myocardium. Main histopathologic lesions were extensive subepicardial and intercardiomyofibers hemorrhages, extensive cardiomyolysis and myocarditis in heart, severe hyperemia and extensive acute tubular necrosis (ATN in kidneys and focal necrosis and retention of bile cholangitis in the liver. In this study, on the basis of the history, observation of the ionophore remnant in the ration, clinical signs, gross and histopathological findings, acute salinomycin intoxication is definitely diagnosed.

  2. Accidental release of chlorine and its impact on urban areas

    Energy Technology Data Exchange (ETDEWEB)

    El-Sheikh, H.A.; Badr, O.A.; El Kadi, H.M.; Hamoda, M.F. [United Arab Emirates Univ., Abu Dhabi (United Arab Emirates). Faculty of Engineering

    1995-12-31

    Among the possible scenarios of accidental releases of chlorine from high pressure cylinders, this paper considers a typical one for the analysis. The calculated transient mass flow rate of chlorine released from a one-tonne cylinder showed that such an accident takes about 10 minutes to evacuate the cylinder. However, the toxic effect in the surrounding atmosphere continues for a longer period (about 20 minutes). The size and location of the toxic cloud at ground level were predicted as functions of time using an EPA-based dispersion model. The results showed a growth of the toxic cloud for some time beyond which it started to decay. For the typical scenario considered in this study, the most dangerous situation generated a toxic cloud with dimensions of 4000 m and 600 m in the downwind and crosswind directions, respectively. A study of the effects of some meteorological parameters on the size and location of the toxic cloud at ground level was also conducted. In general, it was observed that enhancing atmospheric mixing produced larger toxic zones during the early stages of the release and caused an opposite effect during the later ones. This dynamic data was linked to a GIS environment and the time variant was represented using an animation technique for Al-Ain City, United Arab Emirates. Data base information related to physical urban characteristics and population was immediately obtained for the affected areas.

  3. Accidental intoxication with hydrochloric acid and hydrofluoric acid mixture.

    Science.gov (United States)

    Smędra-Kaźmirska, A; Kędzierski, M; Barzdo, M; Jurczyk, Ap; Szram, S; Berent, J

    2014-01-01

    The paper describes a fatal case of accidental ingestion of a mixture of hydrochloric acid and hydrofluoric acid. The man was admitted to hospital, where appropriate treatment, adequate to his condition, was instituted. Numerous ventricular fibrillation episodes, for which the patient was defibrillated repeatedly, were observed during the period of hospitalization. The patient was in a critical condition, with progressive symptoms of hypovolemic shock and multiorgan failure. On the next day after admission, signs of electromechanical dissociation progressing to asystole were noted. The instituted resuscitation procedure proved ineffective and the patient died. Autopsy revealed brownish discoloration of the esophageal, gastric, and small intestinal mucous membranes. Numerous ulcerations without signs of perforation were found both in the esophagus and in the stomach. The mucous membrane of the small intestine demonstrated focal rubefactions, whereas no focal lesions of the large intestinal mucosa were seen. Microscopic investigation of the biopsy specimens collected from the stomach, duodenum and small intestine revealed mucous membrane necrosis foci, reaching the deeper layers of the wall of these organs. The mucous membrane of the large intestine was congested. Bioptates obtained from the lungs indicated the presence of hemorrhagic infarcts and focal extravasations. Poisoning with the aforementioned acids with consequent necrosis of the esophageal, gastric, duodenal and small intestinal walls with hemorrhages to the gastrointestinal tract, as well as extravasations and hemorrhagic infarcts in the lungs was considered to be the cause of death.

  4. Prolonged Toxic Encephalopathy following Accidental 4-Aminopyridine Overdose

    Directory of Open Access Journals (Sweden)

    Maria Ballesta Méndez

    2014-01-01

    Full Text Available Background. 4-Aminopyridine (4-AP is a drug that is used to improve motor fatigue in patients suffering from multiple sclerosis (MS. Medication error can occur, as commercial preparation may not be available in some countries. Case Presentation. A 58-year-old woman with progressive MS presented with status epilepticus. She was receiving 4-AP for more than 3 years. The symptoms started soon after the ingestion of a single pill that was supposed to contain 10 mg 4-AP, but further investigations revealed that each pill had been inadvertently prepared with an 100 mg 4-AP concentration. The patient was admitted to the intensive care unit (ICU for appropriate management (orotracheal intubation, sedation, and antiepileptic drugs. The first electroencephalogram (EEG showed abundant irregular spike-waves on the left central regions. Neurological condition gradually improved from day 7, while the EEG did not reveal any more electrical seizures but was still consistent with toxic encephalopathy. The patient stayed in the ICU until day 13. At discharge from the rehabilitation ward (2.5 months later, the patient had not yet recovered her previous cognitive and functional condition. Conclusion. A single 100 mg 4-AP accidental overdose may cause serious immediate complications, with a slow and incomplete neurological recovery.

  5. ¿Accidente industrial o amputación deliberada?

    Directory of Open Access Journals (Sweden)

    Ponce, Paola

    2005-01-01

    Full Text Available El objetivo de este trabajo es analizar los diferentes aspectos de la práctica de amputaciones durante el período victoriano de Inglaterra tales como: las causas que llevaron a tal práctica, los métodos y técnicas quirúrgicos usados durante el S. XIX así como la evidencia de atrofia y/o asimetría por causa del desuso. Tres casos de amputaciones fueron encontrados en una población industrial en el cementerio Victoriano de St. Pete s Collegiate Church en Wolverhampton (West Midlands, Inglaterra. Las amputaciones fueron realizadas en el miembro superior de una mujer (HB53 y los miembros inferiores de dos hombres (HB86 y (HB129. Se concluye que en los tres casos los individuos sobrevivieron a las amputaciones y que estas fueron realizadas mucho tiempo antes de la muerte. Dos de ellas fueron probablemente realizadas mediante cirugía (HB86 y HB129 mientras que la tercera (HB53 podría ser el resultado de un accidente industrial.

  6. Accidental Cutaneous Burns Secondary to Salbutamol Metered Dose Inhaler

    Directory of Open Access Journals (Sweden)

    Ashutosh Kale

    2010-01-01

    Full Text Available We report a case of accidental cutaneous burns caused by salbutamol metered dose inhaler. A 9-year-old boy underwent dental extraction at a children's hospital and was incidentally noted to have burn injuries on dorsum of both hands. On questioning, the boy revealed that a few days ago his 14-year-old brother, who is an asthmatic, playfully sprayed his salbutamol metered dose inhaler on the back of both his hands with the inhaler's mouth piece being in direct contact with the patient's skin. On examination, there was a rectangular area of erythema with superficial peeling on the dorsum of both hands, the dimensions of which exactly matched those of the inhaler's mouthpiece. It is possible that the injury could have been a chemical burn from the pharmaceutical/preservative/propellant aerosol or due to the physical effect of severe cooling of the skin or mechanical abrasive effect of the aerosol blasts or a combination of some or all the above mechanisms. This case highlights the importance of informing children and parents of the potentially hazardous consequences of misusing a metered dose inhaler.

  7. Accidental deaths caused by electricity in Sweden, 1975-2000.

    Science.gov (United States)

    Lindström, Richard; Bylund, Per-Olof; Eriksson, Anders

    2006-11-01

    This study analyzes accidental fatalities caused by electricity--at work and during leisure time--to evaluate risk factors, the role of alcohol, and to identify possible preventive strategies. In Sweden, data on fatalities by electrocution from 1975 through 2000 were collected from the National Cause-of-Death Register. Additional cases were found in the archives of The Swedish National Electrical Safety Board. Suicides and deaths by lightning were excluded. Two hundred and eighty-five deaths were found, including occupational (n=132), leisure time (n=151), and unknown (n=2). Most deaths were caused by aerial power lines, and the most common place for an electrical injury was a railway area or residential property. Postmortem blood from 20% (n=47) of the tested cases was found positive for alcohol, and these persons were killed mainly during leisure time. During the study period, the overall incidence of electricity-related fatalities has decreased, in spite of increased use of electricity. This indicates that safety improvements have been successful.

  8. Pre-accidental situations highlighted by RECUPERARE method and data

    Energy Technology Data Exchange (ETDEWEB)

    Matahri, N. [Institut de Radioprotection et de Surete Nucleaire (IRSN), 92 - Fontenay-aux-Roses (France)

    2006-07-01

    RECUPERARE method has been developed for operating feedback analysis and built on the French Human Reliability Analysis (HRA) principles. It is used to study the causes of human errors or technical failures occurred in French PWRs and the recovery process of events. Based on an event classification (6 categories) model according to the nature of the link between failure and recovery, the identified and recorded data are: the causes of the defects (technical, human, organizational) and the context in which they appear; the factors of the recovery performance (depending on technical and organizational aspects); a chronological analysis, designed to collect delays between failures and their detection/recovery for each event. About 3600 events reported in French PWRs (1997-2003) had been reviewed through this model. Initially, the weight of factors and the most important factors, which influenced the detection and recovery delay, are defined. For this purpose, the regression Partial Least Square (PLS) is used. Then, to link RECUPERARE results with pre-accidental data, conditional probabilities of events linked between them by a cause and effect relationship are calculated. For this, the Bayesian method with the Bayesian network is built with the PLS obtained results and applied. This constitutes a first approach to take into account in HRA the human and organizational factors highlighted by operating feedback. (author)

  9. Funciones superiores en pacientes con accidente cerebro vascular.

    Directory of Open Access Journals (Sweden)

    Felipe Rodríguez

    2009-07-01

    Full Text Available Los estudios realizados en Chile hasta la fecha no permiten detectar de manera significativa el deterioro neuropsicológico causado por el accidente cerebro vascular (ACV y el impacto que éste tiene en el paciente a nivel de su desenvolvimiento diario y familiar. Con base a esto el objetivo de esta investigación fue elaborar un perfil de deterioro neuropsicológico de las diversas funciones cerebrales superiores causado por un ACV, en un grupo de 50 pacientes de la Unidad de Medicina Física del Hospital San José al cuál se le administró un Protocolo de Evaluación Neuropsicológica, comparándose luego con un grupo control de 50 sujetos evaluados con el mismo protocolo. Se encuentra que sobre un 20% de la población con ACV evaluada presenta deterioro en al menos uno de los ítems evaluados, siendo las funciones ejecutivas, la memoria a largo plazo y la memoria a corto plazo las áreas mayoritariamente afectada en la población evaluada.

  10. Accidental intoxication with hydrochloric acid and hydrofluoric acid mixture

    Directory of Open Access Journals (Sweden)

    Anna Smędra-Kaźmirska

    2014-08-01

    Full Text Available The paper describes a fatal case of accidental ingestion of a mixture of hydrochloric acid and hydrofluoric acid. The man was admitted to hospital, where appropriate treatment, adequate to his condition, was instituted. Numerous ventricular fibrillation episodes, for which the patient was defibrillated repeatedly, were observed during the period of hospitalization. The patient was in a critical condition, with progressive symptoms of hypovolemic shock and multiorgan failure. On the next day after admission, signs of electromechanical dissociation progressing to asystole were noted. The instituted resuscitation procedure proved ineffective and the patient died. Autopsy revealed brownish discoloration of the esophageal, gastric, and small intestinal mucous membranes. Numerous ulcerations without signs of perforation were found both in the esophagus and in the stomach. The mucous membrane of the small intestine demonstrated focal rubefactions, whereas no focal lesions of the large intestinal mucosa were seen. Microscopic investigation of the biopsy specimens collected from the stomach, duodenum and small intestine revealed mucous membrane necrosis foci, reaching the deeper layers of the wall of these organs. The mucous membrane of the large intestine was congested. Bioptates obtained from the lungs indicated the presence of hemorrhagic infarcts and focal extravasations. Poisoning with the aforementioned acids with consequent necrosis of the esophageal, gastric, duodenal and small intestinal walls with hemorrhages to the gastrointestinal tract, as well as extravasations and hemorrhagic infarcts in the lungs was considered to be the cause of death.

  11. Behaviour, development and metal accumulation in striped marsh frog tadpoles (Limnodynastes peronii) exposed to coal mine wastewater.

    Science.gov (United States)

    Lanctôt, C; Bennett, W; Wilson, S; Fabbro, L; Leusch, F D L; Melvin, S D

    2016-04-01

    Coal mining generates large quantities of complex effluent, and this often contains high levels of dissolved solids, suspended solids, metals, hydrocarbons, salts and other compounds. Substantial volumes of mine wastewater are periodically discharged into the environment, through both planned and accidental releases, and this raises concerns about the potential for adverse impacts on aquatic wildlife. There have been few attempts to explore sub-lethal effects of coal mine wastewater on amphibians compared to other organisms, and this is particularly true for Australian species. To address existing knowledge gaps, we exposed striped marsh frog (Limnodynastes peronii) tadpoles to 25, 50 and 100% coal mine wastewater collected from two holding dams (CMW1 and CMW2) located at an open cut mine in Central Queensland, Australia. The exposure lasted for four weeks, after which survival, growth and development, swimming behaviour, and concentrations of metals and metalloids in tail and liver tissues were assessed. Physico-chemical parameters varied considerably between sites, with higher turbidity, nutrients, total and dissolved organic carbon, alkalinity and arsenic (As) concentrations at CMW1, and higher conductivity, salinity, dissolved solids, hardness and sulfate levels at CMW2. There was no mortality in controls and less than 5% mortality in CMW1 treatments, whereas survival was significantly decreased in tadpoles exposed to CMW2 with 40 and 55% mortality in the 50 and 100% treatments, respectively. Development was significantly delayed in 100% CMW1 wastewater, but tadpole size (growth) was not influenced by the exposure. Hepatosomatic indices were significantly increased in tadpoles exposed to 25 and 50% CMW1 but not the 100% treatment group. Exposed tadpoles (predominantly those exposed to CMW1) exhibited increased activity after very short-term exposure (24h), but this did not persist as animals approached metamorphic climax. At the end of the experiment, tadpoles

  12. Protocol for a randomised controlled trial of risk screening and early intervention comparing child- and family-focused cognitive-behavioural therapy for PTSD in children following accidental injury

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    Nixon Reginald DV

    2010-11-01

    Full Text Available Abstract Background Accidental injury represents the most common type of traumatic event to which a child or adolescent may be exposed, with a significant number of these children going on to experience posttraumatic stress disorder (PTSD. However, very little research has examined potential interventions for the treatment of PTSD in these children. The present trial aims to evaluate and compare child- and family-focused versions of a cognitive-behavioural early intervention for PTSD following accidental injury. Methods/Design The principal clinical question under investigation is the efficacy of an early, trauma-focused cognitive-behavioural intervention for the treatment of PTSD in children following accidental injury. Specifically, we compare the efficacy of two active treatments (child-focused and family-focused CBT and a waitlist control (no therapy to determine which is associated with greater reductions in psychological and health-related outcome measures over time. The primary outcome will be a reduction in trauma symptoms on a diagnostic interview in the active treatments compared to the waitlist control and greater reductions in the family-compared to the child-focused condition. In doing so, this project will also trial a method of stepped screening and assessment to determine those children requiring early intervention for PTSD following accidental injury. Discussion The present trial will be one of the first controlled trials to examine a trauma-focused CBT, early intervention for children experiencing PTSD following accidental injury (as opposed to other types of traumatic events and the first within a stepped care approach. In addition, it will provide the first evidence comparing the efficacy of child and family-focused interventions for this target group. Given the significant number of children and adolescents exposed to accidental injury, the successful implementation of this protocol has considerable implications. If

  13. Quantification of nerve agent VX-butyrylcholinesterase adduct biomarker from an accidental exposure.

    Science.gov (United States)

    Solano, Maria I; Thomas, Jerry D; Taylor, James T; McGuire, Jeffrey M; Jakubowski, Edward M; Thomson, Sandra A; Maggio, Vincent L; Holland, Kerry E; Smith, J Richard; Capacio, Benedict; Woolfitt, Adrian R; Ashley, David L; Barr, John R

    2008-01-01

    The lack of data in the open literature on human exposure to the nerve agent O-ethyl-S-(2-diisopropylaminoethyl) methylphosphonothioate (VX) gives a special relevance to the data presented in this study in which we report the quantification of VX-butyrylcholinesterase adduct from a relatively low-level accidental human exposure. The samples were analyzed by gas chromatography-high resolution mass spectrometry using the fluoride ion regeneration method for the quantification of multiple nerve agents including VX. Six human plasma samples from the same individual were collected after the patient had been treated once with oxime immediately after exhibiting signs of exposure. Detection limits of approximately 5.5 pg/mL plasma were achieved for the G-analogue of VX (G-VX). Levels of the G-VX ranged from 81.4 pg/mL on the first day after the exposure to 6.9 pg/mL in the sample taken 27 days after the exposure. Based on the reported concentration of human butyrylcholinesterase in plasma of approximately 80 nM, it can be calculated that inhibition levels of >or= 0.05% of BuChE can be accurately quantified. These data further indicate that the fluoride ion regeneration method is a potentially powerful tool that can be used to assess low-level exposure to VX.

  14. International Olympic Committee consensus statement: harassment and abuse (non-accidental violence) in sport.

    Science.gov (United States)

    Mountjoy, Margo; Brackenridge, Celia; Arrington, Malia; Blauwet, Cheri; Carska-Sheppard, Andrea; Fasting, Kari; Kirby, Sandra; Leahy, Trisha; Marks, Saul; Martin, Kathy; Starr, Katherine; Tiivas, Anne; Budgett, Richard

    2016-09-01

    Despite the well-recognised benefits of sport, there are also negative influences on athlete health, well-being and integrity caused by non-accidental violence through harassment and abuse. All athletes have a right to engage in 'safe sport', defined as an athletic environment that is respectful, equitable and free from all forms of non-accidental violence to athletes. Yet, these issues represent a blind spot for many sport organisations through fear of reputational damage, ignorance, silence or collusion. This consensus statement extends the 2007 IOC Consensus Statement on Sexual Harassment and Abuse in Sport, presenting additional evidence of several other types of harassment and abuse-psychological, physical and neglect. All ages and types of athletes are susceptible to these problems but science confirms that elite, disabled, child and lesbian/gay/bisexual/trans-sexual (LGBT) athletes are at highest risk, that psychological abuse is at the core of all other forms and that athletes can also be perpetrators. Harassment and abuse arise from prejudices expressed through power differences. Perpetrators use a range of interpersonal mechanisms including contact, non-contact/verbal, cyber-based, negligence, bullying and hazing. Attention is paid to the particular risks facing child athletes, athletes with a disability and LGBT athletes. Impacts on the individual athlete and the organisation are discussed. Sport stakeholders are encouraged to consider the wider social parameters of these issues, including cultures of secrecy and deference that too often facilitate abuse, rather than focusing simply on psychopathological causes. The promotion of safe sport is an urgent task and part of the broader international imperative for good governance in sport. A systematic multiagency approach to prevention is most effective, involving athletes, entourage members, sport managers, medical and therapeutic practitioners, educators and criminal justice agencies. Structural and

  15. Biological dose estimation for accidental supra-high dose gamma-ray exposure

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Y., E-mail: yingchen29@yahoo.com.cn [Department of Radiation Toxicology and Oncology, Beijing Institute of Radiation Medicine, 27 Taiping Road, Haidian District, Beijing 100850 (China); Yan, X.K. [Department of Radiation Toxicology and Oncology, Beijing Institute of Radiation Medicine, 27 Taiping Road, Haidian District, Beijing 100850 (China); Department of Radiation Safety, Beijing Institute of Nuclear and Chemical Safety, 14 Guan-cun, Dongcheng District, Beijing 100077 (China); Du, J.; Wang, Z.D.; Zhang, X.Q.; Zeng, F.G.; Zhou, P.K. [Department of Radiation Toxicology and Oncology, Beijing Institute of Radiation Medicine, 27 Taiping Road, Haidian District, Beijing 100850 (China)

    2011-09-15

    To correctly estimate the biological dose of victims accidentally exposed to a very high dose of {sup 60}Co gamma-ray, a new dose-effect curve of chromosomal dicentrics/multicentrics and rings in the supra-high dose range was established. Peripheral blood from two healthy men was irradiated in vitro with doses of {sup 60}Co gamma-rays ranging from 6 to 22 Gy at a dose rate of 2.0 Gy/min. Lymphocytes were concentrated, cultured and harvested at 52 h, 68 h and 72 h. The numbers of dic + r were counted. The dose-effect curves were established and validated using comparisons with doses from the Tokai-mura accident and were then applied to two victims of supra-high dose exposure accident. The results indicated that there were no significant differences in chromosome aberration frequency among the different culture times from 52 h to 72 h. The 6-22 Gy dose-effect curve was fitted to a linear quadratic model Y = -2.269 + 0.776D - 7.868 x l0{sup -3}D{sup 2}. Using this mathematic model, the dose estimates were similar to data from Tokai-mura which were estimated by PCC ring. Whole body average doses of 9.7 Gy and 18.1 Gy for two victims in the Jining accident were satisfactorily given. We established and successfully applied a new dose-effect curve of chromosomal dicentrics plus ring (dic + r) after 6-22 Gy {gamma}-irradiation from a supra-high dose {sup 60}Co gamma-ray accident.

  16. Medical documentation, bioanalytical evidence of an accidental human exposure to sulfur mustard and general therapy recommendations.

    Science.gov (United States)

    Steinritz, Dirk; Striepling, Enno; Rudolf, Klaus-Dieter; Schröder-Kraft, Claudia; Püschel, Klaus; Hullard-Pulstinger, Andreas; Koller, Marianne; Thiermann, Horst; Gandor, Felix; Gawlik, Michael; John, Harald

    2016-02-26

    Sulfur mustard (SM) is a chemical warfare agent (CWA) that was first used in World War I and in several military conflicts afterwards. The threat by SM is still present even today due to remaining stockpiles, old and abandoned remainders all over the world as well as to its ease of synthesis. CWA are banned by the Chemical Weapons Convention (CWC) interdicting their development, production, transport, stockpiling and use and are subjected to controlled destruction. The present case report describes an accidental exposure of three workers that occurred during the destruction of SM. All exposed workers presented a characteristic SM-related clinical picture that started about 4h after exposure with erythema and feeling of tension of the skin at the upper part of the body. Later on, superficial blister and a burning phenomenon of the affected skin areas developed. Similar symptoms occurred in all three patients differing severity. One patient presented sustained skin affections at the gluteal region while another patient came up with affections of the axilla and genital region. Fortunately, full recovery was observed on day 56 after exposure except some little pigmentation changes that were evident even on day 154 in two of the patients. SM-exposure was verified for all three patients using bioanalytical GC MS and LC MS/MS based methods applied to urine and plasma. Urinary biotransformation products of the β-lyase pathway were detected until 5 days after poisoning whereas albumin-SM adducts could be found until day 29 underlining the beneficial role of adduct detection for post-exposure verification. In addition, we provide general recommendations for management and therapy in case of SM poisoning.

  17. Management options for accidental injection of epinephrine from an autoinjector: a case report

    Directory of Open Access Journals (Sweden)

    Mathez Christian

    2009-06-01

    Full Text Available Abstract Introduction Epinephrine autoinjector devices are used with increasing frequency to treat severe anaphylactic reactions. Accidental injection, usually involving a finger, is a potential complication. Case presentation A physician in a Family Practice training program accidentally injected epinephrine into his left thumb while reading the operating instructions of an autoinjector (Epipen®. He developed swelling, pallor, and pain in the thumb. Treatment included topical nitroglycerin, oral vasodilators and warming of the thumb. As expected, none caused an immediate response; however, after 8 hours, the thumb was pink and warm. There was full recovery 2 months after the accident. We reviewed the treatment of accidental epinephrine injection, and found that the use of parenteral adrenergic alpha blocker phentolamine would have produced immediate recovery. Conclusions All health professionals concerned with the use of epinephrine autoinjectors should receive adequate instruction on their use. A regimen for management of accidental epinephrine injection, in particular the use of phentolamine, should be emphasized.

  18. Expression of mature micro-RNA involved in the functioning of p53-dependent system of maintaining the genome stability of the individuals exposed to radiation at clinically relevant doses

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    Shulenina L.V.

    2014-12-01

    Full Text Available Purpose: to explore the content of mature micro-RNA involved in the functioning of p53-dependent system of maintaining the genome stability in the blood of patients in distant time after irradiation at clinically relevant doses and to compare these micro-RNA with the development of malignant tumors in the period of late consequences of radiation injury. Materials and methods. We used the blood samples of patients with acute radiation syndrome (ARS, acute radiation syndrome with the development of local radiation injury (ARS+LRI and local radiation injury (LRI obtained through 1-51 year after radiation injury. The mature mir34a, mir21, mir145, mir16, mir125b, Iet7a which contained in the common fractions of RNA were reverse transcribed by using specific "stem-loop" — primers. The relative amount of micro-RNA in blood of patients by real-time PCR. Statistical analysis of the results was carried out using the non-parametric Mann —Whitney test. Data are presented as median and quartiles, normalized to median of control group accepted for 1. Results. We found a significant reduction of content of mir34a, mir21 in the blood of patients with a diagnosis ARS and the increase of content of mir145 in patients with LRI. Analysis of the individual values of micro-RNA expression in the blood of patients whose cancer was detected, except for patients with a bazalioma, showed consistency of changes with risk of carcinogenesis. Conclusion. For the first time was investigated the functional activity of p53-dependent system of maintaining the genome stability by measuring of micro-RNA in the blood of patients after many years post radiation injury. We found a significant reduction of content of mir34a, mir21 in blood of patients with ARS, and increased mir145 in patients with LRI. Our results suggest that further research with groups of patients, and analysis the dynamics of micro-RNA content would allow for use the micro-RNA as indicators of risk of late

  19. Persistent Seroconversion after Accidental Eye Exposure to Calcifying Nanoparticles

    Science.gov (United States)

    Ciftcioglu, Neva; Aho, Katja M.; McKay, David S.; Kajander, E. Olavi

    2007-01-01

    Biosafety of nanomaterials has attracted much attention recently. We report here a case where accidental human eye exposure to biogenic nanosized calcium phosphate in the form of calcifying nanoparticles (CNP) raised a strong IgG immune response against proteins carried by CNP. The antibody titer has persisted over ten years at the high level. The IgG was detected by ELISA using CNPs propagated in media containing bovine and human serum as antigen. The exposure incident occurred to a woman scientist (WS) at a research laboratory in Finland at 1993. CNP, also termed "nanobacteria", is a unique self-replicating agent that has not been fully characterized and no data on biohazards were available at that time. Before the accident, her serum samples were negative for both CNP antigen and anti-CNP antibody using specific ELISA tests (Nanobac Oy, Kuopio, Finland). The accident occurred while WS was harvesting CNP cultures. Due to a high pressure in pipetting, CNP pellet splashed into her right eye. Both eyes were immediately washed with water and saline. The following days there was irritation and redness in the right eye. These symptoms disappeared within two weeks without any treatment. Three months after the accident, blood and urine samples of WS were tested for CNP cultures (2), CNP-specific ELISA tests, and blood cell counts. Blood cell counts were normal, CNP antigen and culture tests were negative. A high IgG anti-CNP antibody titer was detected (see Figure). The antibodies of this person have been used thereafter as positive control and standard in ELISA manufacturing (Nano-Sero IgG ELISA, Nanobac Oy, Kuopio, Finland).

  20. Fire exposed aluminium structures

    NARCIS (Netherlands)

    Maljaars, J.; Fellinger, J.H.H.; Soetens, F.

    2006-01-01

    Material properties and mechanical response models for fire design of steel structures are based on extensive research and experience. Contrarily, the behaviour of aluminium load bearing structures exposed to fire is relatively unexplored. This article gives an overview of physical and mechanical pr

  1. Eficiência térmica de telhas onduladas de fibrocimento aplicadas em abrigos individuais para bezerros expostos ao sol e à sombra Thermal efficiency of fiber cement corrugated sheets applied to individual housing for calves exposed to sun and shade

    Directory of Open Access Journals (Sweden)

    Juliano Fiorelli

    2012-01-01

    Full Text Available Este trabalho apresenta um estudo da eficiência térmica de coberturas de bezerreiros individuais expostas ao sol e à sombra, por meio de termografia infravermelha, temperatura interna e índices de conforto térmico. Foram avaliados quatro bezerreiros, três expostos ao sol, a saber: (i cobertos com telhas de fibrocimento sem amianto - pintadas de branco, (ii sem pintura e (iii com sombrite posicionado internamente aos bezerreiros, à distância de 0,10m da face inferior da telha. O quarto bezerreiro foi instalado em área sombreada e coberto com telhas de fibrocimento sem pintura. As coletas de dados foram realizadas durante 21 dias, nos horários das 11h00min, 14h00min e 17h00min. Os resultados mostraram variações significativas na temperatura de superfície das coberturas e nos índices de conforto térmico, entre os tratamentos expostos ao sol e à sombra, para todos os horários avaliados. As imagens termográficas infravermelhas mostraram-se eficientes para melhor compreensão dos processos de transferência de calor da cobertura para o interior das instalações.This research presents a study of roof thermal efficiency in individual housing for calves exposed to sun and shade through infrared thermography, internal temperature and thermal comfort indexes. Four different individual housing for calves covered with asbestos-free fiber-cement corrugated sheets were evaluated. Three of them were directly exposed to the sun: (i corrugated sheets painted white in the external surface, (ii corrugated sheets without painting and (iii with screen shade fabric installed 0.10m under de internal surface of the corrugated sheet. The fourth individual housing was installed in the shade area and covered with unpainted corrugated fiber-cement sheets. The analysis was taken for 21 days at 11h00min, 14h00min and 17h00min. The results indicate significant variations in the roofing surface temperature and thermal comfort indexes among the treatments

  2. Análisis de accidentes severos en contenciones nucleares

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    Goicolea Ruigómez, José María

    1992-04-01

    Full Text Available Analysis for severe accidents has recently been added to the long list of requisites imposed on nuclear power plants. In this work we study the rationale and justiflcation for this type of analysis. Calculations for the structural response of the containment buildings can be performed on the computer using advanced nonlinear Finite Element codes. A state of the art review of these methods is carried out, proposing a methodology based on analysis by numerical methods with experimental validation. Additionally we present some results obtained by the authors for the analysis of both reinforced concrete and steel containments. The concluding remarks show the validity of the proposed methodology, as well as the evidence of a large security margin in the containments, due mainly to the conservatisms in the design stage.

    El análisis frente a accidentes severos ha venido a añadirse recientemente a la larga lista de requisitos impuestos a las centrales nucleares. En este trabajo se pretende estudiar la problemática y justificación de este tipo de análisis. El cálculo de la respuesta de la contención se puede realizar en el ordenador mediante métodos avanzados de elementos finitos no lineales. Se hace una revisión del estado de la técnica en estos métodos, proponiendo una metodología basada en el análisis mediante modelos numéricos con validación experimental. Se presentan asimismo los resultados de análisis realizados, para contenciones tanto de hormigón armado como metálicas. Las conclusiones del trabajo establecen la validez de la metodología empleada, así como la constatación de un amplio margen de seguridad existente en las contenciones evaluadas, debido a los conservadurismos del proceso de diseño original.

  3. Accidentes de trabajo fatales y violencia interpersonal en Brasil, 2000-2010

    Directory of Open Access Journals (Sweden)

    Vilma Sousa Santana

    2013-01-01

    Full Text Available En el presente estudio se estima la mortalidad proporcional por accidentes de trabajo provocados por violencia interpersonal en Brasil, entre 2000 y 2010. Se analizaron los datos del Sistema de Información sobre Mortalidad, basados en los informes estadísti- cos de defunción del Ministerio de Salud de Brasil, los cuales incluyen un campo para el registro de accidentes de trabajo que debe ser completado en toda defunción por causas externas. Se identificaron 1.368.732 casos de defunciones por causas externas, 31.576 (2,3% por accidentes de trabajo y solo 226 (0,02% por accidentes de trabajo con violen- cia interpersonal. Cerca del 80% de los informes estadísticos de defunción no tenían el campo “accidente de trabajo” completado. La mayor cantidad de casos ocurrió entre hom- bres (94,3% de 25-34 años, con nivel de escolaridad medio, ubicados en la región sudeste y noreste, que trabajan principalmente en la producción de bienes y servicios industriales y la actividad agropecuaria. La mayoría de los casos fueron causados por armas de fuego, seguidos por armas blancas, con un aumento relativo de estos últimos en el período estu- diado. Los resultados sugieren un gran subregistro de diagnósticos que reconocen la rela- ción con el trabajo. Se hace necesaria una mejor capacitación en el llenado de los informes estadísticos, así como estudios que cuantifiquen el subregistro de accidentes de trabajo y accidentes de trabajo con violencia interpersonal.

  4. Airways microbiota: Hidden Trojan horses in asbestos exposed individuals?

    Science.gov (United States)

    Magouliotis, Dimitrios E; Tasiopoulou, Vasiliki S; Molyvdas, Paschalis-Adam; Gourgoulianis, Konstantinos I; Hatzoglou, Chrissi; Zarogiannis, Sotirios G

    2014-11-01

    Malignant pleura mesothelioma (MPM) is a rare type of cancer with devastating prognosis, which develops in the pleural cavity from transformed mesothelium. MPM has been directly associated with asbestos exposure however there are aspects of the pathophysiology involved in the translocation of asbestos fibers in the pleura that remain unclear. Here, we propose and discuss that certain proteins secreted by airways symbiotic microbiota create membrane pores to the airway epithelial cells, through which asbestos fibers can penetrate the lung parenchyma and reach the sub-pleural areas. We evaluate this hypothesis using data from the published literature regarding the airways microbiota toxins such as cholesterol-dependent cytolysins (CDCs).

  5. Microdistribution and Long-Term Retention of 239Pu (NO3)4 in the Respiratory Tracts of an Acutely Exposed Plutonium Worker and Experimental Beagle Dogs

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, Christopher E.; Wilson, Dulaney A.; Brooks, Antone L.; McCord, Stacey; Dagle, Gerald E.; James, Anthony C.; Tolmachev, Sergei Y.; Thrall, Brian D.; Morgan, William F.

    2012-11-01

    The long-term retention of inhaled soluble forms of plutonium raises concerns as to the potential health effects in persons working in nuclear energy or the nuclear weapons program. The distributions of long-term retained inhaled plutonium-nitrate [239Pu (NO3)4] deposited in the lungs of an accidentally exposed nuclear worker (Human Case 0269) and in the lungs of experimentally exposed beagle dogs with varying initial lung depositions were determined via autoradiographs of selected histological lung, lymph node, trachea, and nasal turbinate tissue sections. These studies showed that both the human and dogs had a non-uniform distribution of plutonium throughout the lung tissue. Fibrotic scar tissue effectively encapsulated a portion of the plutonium and prevented its clearance from the body or translocation to other tissues and diminished dose to organ parenchyma. Alpha radiation activity from deposited plutonium in Human Case 0269 was observed primarily along the sub-pleural regions while no alpha activity was seen in the tracheobronchial lymph nodes of this individual. However, relatively high activity levels in the tracheobronchial lymph nodes of the beagles indicated the lymphatic system was effective in clearing deposited plutonium from the lung tissues. In both the human case and beagle dogs, the appearance of retained plutonium within the respiratory tract was inconsistent with current biokinetic models of clearance for soluble forms of plutonium. Bound plutonium can have a marked effect on the dose to the lungs and subsequent radiation exposure has the potential increase in cancer risk.

  6. Microdistribution and long-term retention of 239Pu (NO3)4 in the respiratory tracts of an acutely exposed plutonium worker and experimental beagle dogs.

    Science.gov (United States)

    Nielsen, Christopher E; Wilson, Dulaney A; Brooks, Antone L; McCord, Stacey L; Dagle, Gerald E; James, Anthony C; Tolmachev, Sergei Y; Thrall, Brian D; Morgan, William F

    2012-11-01

    The long-term retention of inhaled soluble forms of plutonium raises concerns as to the potential health effects in persons working in nuclear energy or the nuclear weapons program. The distributions of long-term retained inhaled plutonium-nitrate [(239)Pu (NO(3))(4)] deposited in the lungs of an accidentally exposed nuclear worker (Human Case 0269) and in the lungs of experimentally exposed beagle dogs with varying initial lung depositions were determined via autoradiographs of selected histologic lung, lymph node, trachea, and nasal turbinate tissue sections. These studies showed that both the human and dogs had a nonuniform distribution of plutonium throughout the lung tissue. Fibrotic scar tissue effectively encapsulated a portion of the plutonium and prevented its clearance from the body or translocation to other tissues and diminished dose to organ parenchyma. Alpha radiation activity from deposited plutonium in Human Case 0269 was observed primarily along the subpleural regions while no alpha activity was seen in the tracheobronchial lymph nodes of this individual. However, relatively high activity levels in the tracheobronchial lymph nodes of the beagles indicated the lymphatic system was effective in clearing deposited plutonium from the lung tissues. In both the human case and beagle dogs, the appearance of retained plutonium within the respiratory tract was inconsistent with current biokinetic models of clearance for soluble forms of plutonium. Bound plutonium can have a marked effect on the dose to the lungs and subsequent radiation exposure has the potential to increase cancer risk.

  7. Patterns and Trends in Accidental Poisoning Deaths: Pennsylvania's Experience 1979-2014.

    Directory of Open Access Journals (Sweden)

    Lauren C Balmert

    Full Text Available The purpose of this study was to examine county and state-level accidental poisoning mortality trends in Pennsylvania from 1979 to 2014.Crude and age-adjusted death rates were formed for age group, race, sex, and county for accidental poisonings (ICD 10 codes X40-X49 from 1979 to 2014 for ages 15+ using the Mortality and Population Data System housed at the University of Pittsburgh. Rate ratios were calculated comparing rates from 1979 to 2014, overall and by sex, age group, and race. Joinpoint regression was used to detect statistically significant changes in trends of age-adjusted mortality rates.Rate ratios for accidental poisoning mortality in Pennsylvania increased more than 14-fold from 1979 to 2014. The largest rate ratios were among 35-44 year olds, females, and White adults. The highest accidental poisoning mortality rates were found in the counties of Southwestern Pennsylvania, those surrounding Philadelphia, and those in Northeast Pennsylvania near Scranton.The patterns and locations of accidental poisoning mortality by race, sex, and age group provide direction for interventions and policy makers. In particular, this study found the highest rate ratios in PA among females, whites, and the age group 35-44.

  8. Accidental benzene release risk assessment in an urban area using an atmospheric dispersion model

    Science.gov (United States)

    Truong, Son C. H.; Lee, Myong-In; Kim, Ganghan; Kim, Dongmin; Park, Jong-Hwa; Choi, Sung-Deuk; Cho, Gi-Hyoug

    2016-11-01

    This study applied the American Meteorological Society and Environmental Protection Agency Regulatory Model (AERMOD) to assess the risk caused by an accidental release and dispersion of the toxic chemical benzene in the vicinity of a highly populated urban area. The modeling domain encompasses the Korean megacity of Ulsan, which includes two national industrial complexes and is characterized by a complex coastal terrain. Multiple AERMOD simulations were conducted for an assumed emission scenario using background wind data from August between 2009 and 2013. The series of experiments produced the spatial accident probability patterns for different concentration levels during daytime and nighttime scenarios based on the corresponding dominant wind patterns. This study further quantifies the potential accident risk based on the number of affected individuals by combining the accident probability with the indoor and outdoor population estimates. The chemical gas dispersion characteristics depend on various local meteorological conditions, such as the land-sea breeze direction, which alternates between daytime and nighttime, and the atmospheric stability. The results reveal that benzene dispersion affects a much larger area during the nighttime owing to the presence of a nocturnal stable boundary layer with significant temperature stratification. The affected area is smaller during the daytime owing to decreased stability and enhanced vertical mixing in the boundary layer. The results include a high degree of uncertainty during the nighttime owing to weak wind speeds and the lack of a prevailing wind direction, which impact the vulnerable area. However, vulnerable areas are more effectively identified during the daytime, when more consistent meteorological conditions exist. However, the potential risk becomes much lower during the nighttime owing to a substantial reduction of the outdoor population.

  9. Magical Empiricism and 'Exposed Being' in Medicine and Traditional Healing.

    Science.gov (United States)

    Thornton, Robert

    2015-01-01

    Southern African traditional healers often generalize too broadly from discrete ('accidental') instances of success, partly to recruit a clientele, while biomedicine frequently reasons incorrectly from the general to the specific. Both logics are based on empirical observations, but are inversions of each other; these I characterize as 'magical empiricism.' 'Magic' functions as a metapragmatic discourse to recruit a clientele from a skeptical public that doubts the efficacy of any therapeutic interventions, and it acts in parallel with other practical (and efficacious) healing acts. I introduce the concept of 'exposed beings' to describe locally specific constructions of the person as patient and healer. This helps to explain the existence and enduring appeal of many different medical practices and beliefs in South Africa, but I suggest that 'medical parallelism' rather than 'pluralism' might be more accurate.

  10. Germline mutations in people descendants occupationally exposed to ionizing radiation from Cesium 137; Mutacoes germinativas na prole de pessoas expostas ocupacionalmente a radiacao ionizante de Cesio 137

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Juliana Ferreira da

    2016-07-01

    The radiological accident in Goiania in 1987, resulted in a serious episode of human contamination, animal, plant and environmental were exposed to Cesium 137 chloride ({sup 137}CsCl) that caused contamination and accidental and occupational exposure to ionizing radiation. Ionizing radiation is one of the environmental components that causes most cellular stress in complex organisms. Exposure to ionizing radiation induces breaks in nucleic acids, especially, DNA double and single strand breaks. Chromosomal microarray analysis is an important tool for the detection and microdeletion and microduplications in the genomes. In this study we proposed to analyze the effect of exposure to RI on the formation of CNVs in an exposed human population occupationally to ionizing radiation from Cesium 137 during the accident in Goiania. The exposed group consisted of 07 families, of which at least one parent was occupationally exposed to ionizing radiation from Cesium 137, including a total of 25 individuals, do not know the absorbed dose of the military who were occupationally exposed to ionizing radiation. 11 families with a group of individuals not exposed to IR was used as control were used including a total of 33 individuals with no history of exposure to RI. The genotyping microarray was conducted in CytoScan HD system (Affymetrix®) without then analyzes was performed in ChAS® software. The statistical tests used were: Shapiro-Wilk, Mann- Whitney U, Spearman correlation, discriminant function analysis, binomial test, χ{sup 2} test. All analyzes were performed using the statistical package SPSS 21.0, with a significance level of 5% (p <0.05). The frequency of CNVs were estimated loss / generation, gain / generation and burden / generation, representing 3,9 x 10{sup -5}, 6,8 x 10{sup -6} and 4,6 x 10{sup -5} respectively for the exposed group. For the control group, the frequencies were 2,1 x 10{sup -5}, 5,9 x 10{sup -6} and 3,1 x 10{sup -5} respectively. Thus, the

  11. Materiales didácticos para los contenidos de enfermedad y accidente en la etapa infantil

    OpenAIRE

    Bocos Urdiales, Elías Javier

    2015-01-01

    Este trabajo, es una programación didáctica, que responde a la necesidad de crear materiales para la enseñanza dedicada a la actuación y prevención de accidentes y enfermedades tanto en lo personal, como en lo colectivo tanto en el aula como en los pasillos, patio y zonas comunes. En relación a los accidentes se realizaran materiales para la prevención de los accidentes en el ámbito del centro escolar; y además de la prevención daremos pautas de actuación a los alumnos de tal manera que se...

  12. Insomnia medication use and the probability of an accidental event in an older adult population

    Directory of Open Access Journals (Sweden)

    Alon Y Avidan

    2010-11-01

    Full Text Available Alon Y Avidan1, Liisa A Palmer2, Justin F Doan3, Robert W Baran31UCLA Department of Neurology, Los Angeles, CA, USA; 2Thomson Reuters, Washington, DC, USA; 3Takeda Global Research and Development Center, Deerfield, IL, USAObjective: This study examined the risk of accidental events in older adults prescribed a sedating antidepressant, long-acting benzodiazepine, short-acting benzodiazepine, and nonbenzodiazepine, relative to a reference group (selective melatonin receptor agonist.Methods: This was a retrospective cohort analysis of older adults (≥65 years with newly initiated pharmacological treatment of insomnia. Data were collected from the Thomson MarketScan® Medicare Supplemental and Coordination of Benefits databases (January 1, 2000, through June 30, 2006. Probit models were used to evaluate the probability of an accidental event.Results: Data were analyzed for 445,329 patients. Patients taking a long-acting benzodiazepine (1.21 odds ratio [OR], short-acting benzodiazepine (1.16 OR, or nonbenzodiazepine (1.12 OR had a significantly higher probability of experiencing an accidental event during the first month following treatment initiation compared with patients taking the reference medication (P < 0.05 for all. A significantly higher probability of experiencing an accidental event was also observed during the 3-month period following the initiation of treatment (1.62 long-acting benzodiazepine, 1.60 short-acting benzodiazepine, 1.48 nonbenzodiazepine, and 1.56 sedating antidepressant; P < 0.05.Conclusions: Older adults taking an SAD or any of the benzodiazepine receptor agonists appear to have a greater risk of an accidental event compared with a reference group taking an MR.Keywords: insomnia, accidental events, benzodiazepine receptor agonist, melatonin receptor agonist, older adults

  13. El estudio del factor humano en accidentes de aviación

    OpenAIRE

    Sánchez Rubio, Lina María

    2010-01-01

    El factor humano ha sido considerado causa o contribución del 70 al 80% de los accidentes de aviación en el mundo, y constituye una prioridad en investigación para la seguridad aérea. Las estadísticas muestran que los índices y causas de accidentes de aviación se mantienen constantes, e identifican una importante diferencia entre regiones. La investigación científica requiere de nuevas y complementarias aproximaciones para la explicación y comprensión del factor humano en aviación. Los médico...

  14. Inhaled Surfactant in the treatment of accidental Talc Powder inhalation: a new case report

    Directory of Open Access Journals (Sweden)

    Lo Piparo Caterina

    2011-09-01

    Full Text Available Abstract The use of talcum powder is incorrectly part of the traditional care of infants. Its acute aspiration is a very dangerous condition in childhood. Although the use of baby powder has been discouraged from many authors and the reports of its accidental inhalation have been ever more rare, sometimes new cases with several fatalities have been reported. We report on a patient in which accidental inhalation of baby powder induced severe respiratory difficulties. We also point out the benefits of surfactant administration. Surfactant contributed to the rapid improvement of the medical and radiological condition, preventing severe early and late complications and avoiding invasive approaches.

  15. Physical reconstruction of the radiological accident of Chilca (Lima - Peru); Reconstruccion fisica del accidente radiologico de Chilca (Lima - Peru)

    Energy Technology Data Exchange (ETDEWEB)

    Lachos, A. [Instituto Nacional de Enfermedades Neoplasicas, Departamento de Radioterapia, Av. Angamos Este 2520, Surquillo, Lima (Peru); Marquez, J. F., E-mail: alachosd1271@yahoo.com [Univesidad Nacional Mayor de San Marcos, Facultad de Ciencias Fisicas, C. German Amezaga 375, Ciudad Univesitaria, Lima (Peru)

    2014-08-15

    The radiological accident happened in the Chilca District, the Canete County at 60 km to the south of Lima-Peru, during the night of January 11 to 12, 2012. The physical reconstruction of the accident was carried out in January 21, 2012, by means of the information gathering administrative and technical of the radioactive source as well as of the installation, the personnel and the involved procedures in the accidental event, information of the space geometry where the event took place. The preliminary information indicates that the source could have been locked in the guide tube of the equipment, next to the collimator in the first takes radiographic. The radiation monitors were not activated on the procedure, impeding this way, not to realize the flaw and causing that the personnel were exposed to the radiation during the whole work period. Their hands and especially their fingers would have been only to some millimeters of the source. With the obtained information and the measurements of the exposure rates of the radioactive source, was carried out the dose calculation to total body, the dose received in the hands and the dose received in the index finger of the left hand. The accident happened by operative procedure breach, by lack of training of the operators. The physical reconstruction of the accident contributes fundamental information for the decisions taking in the medical management of the accidents by radiation. (author)

  16. Accidental nuclear excursion Recuplex operation 234-5 facility. Final report: Date of incident: April 7, 1962

    Energy Technology Data Exchange (ETDEWEB)

    1962-08-01

    On Saturday morning, April 7, 1962, at about 1059 Armed Forces time, an accidental nuclear excursion occurred in the plutonium waste recovery facility (Recuplex) of the 234-5 Building. This excursion did not result in any mechanical damage or spread of contamination. Three employees of the General Electric Company received overexposures to gamma and neutron radiation. None were fatally exposed; in each case the overexposure was recognized promptly, and following medical observation and testing the men were released to return to work. In compliance with AEC Manual Chapter 0703, an AEC-HAPO committee composed of two AEC employees and five General Electric employees was appointed by the Manger, HOO, with the concurrence of the General Manager, HAPO, to conduct an investigation of the incident. The committee`s purpose was to determine the cause, nature, and extent of the incident, and recommend action to be taken by others to minimize or preclude future incidents of this magnitude. A study of operating practices and operating conditions that appeared to exist prior to, during, and subsequent to the accident was made by the committee. The committee believes that this report provides sufficient information to answer questions which may arise as a result of the criticality incident except those relating to its cause.

  17. Accidentes ocupacionales y conocimiento sobre precauciones universales en internos universitarios costarricenses

    Directory of Open Access Journals (Sweden)

    Álvaro Rivera-Valdivia

    2005-04-01

    Full Text Available Justificación y objetivo: los internos universitarios (estudiantes de medicina en su último año son vulnerables a accidentes ocupacionales con agujas y otros objetos cortantes, especialmente debido a su inexperiencia y falta de entrenamiento aunados a su deseo de realizar una serie de nuevas actividades y procedimientos. No existe información en nuestro país con respecto a la frecuencia de este tipo de accidentes en internos universitarios de la carrera de medicina. El objetivo del presente estudio fue estudiar la frecuencia y tipo de accidentes ocupacionales sufridos con mayor frecuencia por internos de medicina y evaluar su conocimiento sobre precauciones universales. Metodología: Se realizó un estudio descriptivo de corte transversal a través de una encuesta directa y anónima. De todos los internos de medicina que trabajaban en el Valle Central de octubre de 2001 a enero de 2002 se seleccionó una muestra aleatoria de 201 internos (poder 95%, error 5%. A la población seleccionada se le aplicó una encuesta precodificada, la cual consistía en 20 preguntas estructuradas, la mayoría cerradas y tres abiertas relacionadas con la ocurrencia de accidentes ocupacionales en los médicos internos, número, tipo, acciones tomadas tras el accidente y conocimientos sobre precauciones universales. Posteriormente se hizo un análisis descriptivo de los resultados obtenidos. Resultados: de todos los participantes, 90% habían trabajado más de 3 meses como médicos internos. Más de la mitad habían realizado al menos 3 meses de rotación en una área médica y 3 meses en una área quirúrgica. La muestra incluyó estudiantes de 5 universidades diferentes. Sólo un 37% de los internos encuestados habían recibido la vacunación contra virus de la hepatitis B. Del total de internos, 64% admitió haber sufrido al menos un accidente ocupacional con sangre de algún paciente, un 20% admitió haber sufrido 3 o 4 accidentes. De los internos que

  18. 36 CFR 1230.10 - Who is responsible for preventing the unlawful or accidental removal, defacing, alteration, or...

    Science.gov (United States)

    2010-07-01

    ... MANAGEMENT UNLAWFUL OR ACCIDENTAL REMOVAL, DEFACING, ALTERATION, OR DESTRUCTION OF RECORDS § 1230.10 Who is... destruction, removal, alteration or defacement of records; (c) Implement and disseminate policies and... preventing the unlawful or accidental removal, defacing, alteration, or destruction of records?...

  19. Accidental exposure to isocyanate fumes in a group of firemen.

    Science.gov (United States)

    Axford, A T; McKerrow, C B; Jones, A P; Le Quesne, P M

    1976-05-01

    A total of 35 firemen involved in fighting a fire in a factory in which polyurethane foam was made were exposed to fumes of toluene di-isocyanate from two large storage tanks which were damaged during the fire, resulting in massive spillage. Most of the men experienced symptoms during the fire or during the three weeks after it. The symptoms were mainly gastrointestinal, respiratory, or neurological. Altogether 15 men described gastrointestinal symptoms which subsided within two days of onset. Respiratory symptoms were described by 31 men and were most pronounced during the three days after the fire, thereafter tending to improve. The neurological findings are described separately. When the men were reviewed at six months there was a suggestion that some of them might have sustained long-term damage to the respiratory tract, and almost four years later 20 men had persistent respiratory symptoms. Serial measurements of ventilatory capacity revealed a marked decline in the first six months although this was not sustained.

  20. Radioecological studies on terrestrial food chain analysis for accidental release

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yong Ho; Lee, Jeong Ho; Lee, Hyun Duk [and others

    2000-03-01

    For investigating the contamination pathways of major radionuclides in staple food crops, greenhouse experiments in which rice, Chines cabbage and radish were exposed to mixed {gamma} radionuclides of Mn-54, Co-60, Sr-85, Ru-103 and Cs-134 and H-3 at different growth stages, were conducted to generate data on parameters concerning the direct contamination of those crops. Experiments of the exposure to iodine gas were also performed for rice and radish at their various growth stages to obtain contamination parameters of elemental iodine. Based on data obtained from the experiments mentioned above, a database program was constructed to make it possible to search parameter values for different radionuclides, crops and deposition times in an easy way have an graphic output of the variation in the contamination parameter with deposition times. Paddy-field soils were collected from 5 or 6 places around Kori and Youngkwang NPPs and physicochemical properties and background radioactivity levels of the soils were investigated. Soil-to-rice transfer factors of Sr-90 and Cs-137 in the collected soils were determined for different RI application times. For Kori soils, transfer factors were also measured in the second year to investigate the yearly variation. In addition, the conceptual design of an automatized experimental greenhouse was performed to be used as a basic material for a detailed design for the construction in the future.

  1. Pathophysiology of the systemic inflammatory response after major accidental trauma

    DEFF Research Database (Denmark)

    Brøchner, Anne Craveiro; Toft, Palle

    2009-01-01

    ABSTRACT: BACKGROUND: Purpose of the present study was to describe the pathophysiology of the systemic inflammatory response after major trauma and the timing of final reconstructive surgery. Methods: An unsystematic review of the medical literature was performed and articles pertaining to the in......ABSTRACT: BACKGROUND: Purpose of the present study was to describe the pathophysiology of the systemic inflammatory response after major trauma and the timing of final reconstructive surgery. Methods: An unsystematic review of the medical literature was performed and articles pertaining...... to the inflammatory response to trauma were obtained. The literature selected was based on the preference and clinical expertise of authors. Discussion: The inflammatory response consists of hormonal metabolic and immunological components and the extent correlates with the magnitude of the tissue injury. After trauma...... and uncomplicated surgery a delicate balance between pro- and anti-inflammatory mediators is observed.Trauma patients are, however, often exposed, not only to the trauma, but to several evens in the form of initial surgery and later final reconstructive surgery. In this case immune paralysis associated...

  2. Tratamiento de la hipertensión arterial en accidente cerebrovascular

    OpenAIRE

    Luna Vela, Fredy Andrés

    2013-01-01

    Revisión sistemática de la literatura en la que se discuten las controversias del manejo de la presión arterial en las emergencias neurológicas agudas cerebrovasculares como accidente cerebrovascular isquémico, hemorrágico y hemorragia subaracnoidea.

  3. The accidental city : violence, economy and humanitarianism in Kakuma refugee camp Kenya

    NARCIS (Netherlands)

    Jansen, B.J.

    2011-01-01

    In this research I examine social ordering processes in Kakuma refugee camp in Kenya. I view the camp as an accidental city, by which I challenge the image of the camp as a temporary and artificial waiting space or a protracted refugee crisis per se. The reference to the city is both metaphorical

  4. Accidental Epipen injection into a digit - the value of a Google search.

    Science.gov (United States)

    Turner, M J A; Purushotham, A D

    2004-05-01

    Despite the lack of awareness by the clinicians consulted of the most suitable treatment for accidentally injected epinephrine, this patient was successfully treated due mainly to the ability of clinicians on-site to access the Internet in the A&E department. A broad search engine such as Google can be an invaluable tool in finding important clinical information rapidly.

  5. [Accidental injection of adrenaline in a finger with EpiPen].

    Science.gov (United States)

    Kaspersen, J; Vedsted, P

    1998-11-01

    We report a case of accidental injection of 0.3 mg epinephrine in the right pollux. The actual case was treated with systemic nitroglyceride and immersion of the finger in hot water. A review of the literature shows that the adequate treatment is local infiltration with Phentholamine Mesylate. There is a need to describe this treatment in conventional literature.

  6. Accidental Epipen injection into a digit - the value of a Google search.

    Science.gov (United States)

    Turner, M. J. A.; Purushotham, A. D.

    2004-01-01

    Despite the lack of awareness by the clinicians consulted of the most suitable treatment for accidentally injected epinephrine, this patient was successfully treated due mainly to the ability of clinicians on-site to access the Internet in the A&E department. A broad search engine such as Google can be an invaluable tool in finding important clinical information rapidly. PMID:15140311

  7. Insertion of an intrathecal catheter following accidental dural puncture : a meta-analysis

    NARCIS (Netherlands)

    Heesen, M.; Kloehr, S.; Rossaint, R.; Walters, M.; Straube, S.; van de Velde, M.

    2013-01-01

    Background: Inserting an intrathecal catheter after accidental dural puncture in parturients to prevent postdural puncture headache is becoming increasingly popular. We aimed to identify relevant published articles investigating this intervention and subject data to a meta-analysis. Methods: A syste

  8. Multiple scattering and accidental coincidences in the J-PET detector simulated using GATE package

    CERN Document Server

    Kowalski, P; Wiślicki, W; Raczyński, L; Bednarski, T; Białas, P; Bułka, J; Czerwiński, E; Gajos, A; Gruntowski, A; Kamińska, D; Kapłon, Ł; Kochanowski, A; Korcyl, G; Kowal, J; Kozik, T; Krzemień, W; Kubicz, E; Niedźwiecki, Sz; Pałka, M; Rudy, Z; Salabura, P; Sharma, N G; Silarski, M; Słomski, A; Smyrski, J; Strzelecki, A; Wieczorek, A; Wochlik, I; Zieliński, M; Zoń, N

    2015-01-01

    Novel Positron Emission Tomography system, based on plastic scintillators, is developed by the J-PET collaboration. In order to optimize geometrical configuration of built device, advanced computer simulations are performed. Detailed study is presented of background given by accidental coincidences and multiple scattering of gamma quanta.

  9. The Costs of Cultural Change: Accidental Injury and Modernization among the Papago Indians

    Science.gov (United States)

    Hackenberg, Robert A.; Gallagher, Mary M.

    1972-01-01

    Several theories are examined suggesting that stress associated with modernization is responsible for excesses of accidental injuries among American Indians. A preliminary version of this paper was presented at the annual meetings of the American Anthropological Association, New York, 1971. (FF)

  10. INTERNAL BALLOON TAMPONADE - A NONSURGICAL METHOD FOR REMOVAL OF ACCIDENTALLY PLACED SHEATHS FROM THE SUBCLAVIAN ARTERY

    NARCIS (Netherlands)

    VANDIJK, RB; DENHEIJER, P; DEMUINCK, E; LIE, KI

    1993-01-01

    One of the possible complications of subclavian vein puncture is accidental puncture of the subclavian artery. If this is not noted immediately after the puncture, insertion of a large bore sheath in the subclavian artery is likely to follow. We describe our experience with a new method that enables

  11. Estrategia de Inversiones Basada en Accidentes Aéreos: ¿Hay Retornos Anormales?

    Directory of Open Access Journals (Sweden)

    Marcos Rosa Costa

    2013-06-01

    Full Text Available El presente trabajo buscó investigar si una estrategia de inversiones basada en accidentes aéreos generaría retornos anormales. Fue efectuado un estudio de eventos considerándose todos los accidentes aéreos ocurridos en el período de 1998 a 2009 y los datos de las compañías aéreas y de los fabricantes de las respectivas aeronaves que poseían acciones negociadas en las bolsas de valores, cuando del acontecimiento del evento. Los tests realizados se basaron en el modelo de Campbel, Lo y Mackinlay (1997, para definición de retornos anormales, por medio de una regresión lineal entre el retorno de las acciones de esas empresas y el retorno del portafolio de mercado utilizado como benchmark. Así fue posible proyectar los retornos futuros esperados para las acciones de las compañías aéreas y fabricantes y compararlos a los resultados efectivamente obtenidos en el acontecimiento del evento. El resultado obtenido sugiere que una estrategia de inversiones basada en accidentes aéreos sería viable y que retornos anormales podrían ser obtenidos en el período inmediatamente posterior a un accidente aéreo.

  12. Management of accidental dural puncture and post-dural puncture headache after labour: a Nordic survey

    DEFF Research Database (Denmark)

    Darvish, B; Gupta, A; Alahuhta, S

    2011-01-01

    a major risk with epidural analgesia is accidental dural puncture (ADP), which may result in post-dural puncture headache (PDPH). This survey was conducted to explore the incidence of ADP, the policy for management of PDPH and the educational practices in epidural analgesia during labour in the N...

  13. Intraperitoneal granulomatous foreign body reaction after accidental perforation of the abdominal wall. Case report

    DEFF Research Database (Denmark)

    Lanng, C; Winther-Nielsen, H; Hougen, H P

    2013-01-01

    After an accidental perforation by a wooden stake of the abdominal wall and distal ileum a 28-year-old man developed an aggressive granulomatous foreign body reaction of the greater omentum with high fever and abdominal pain. The patient was cured by omental resection and prednisone treatment....

  14. [Risk of acute hepatic insufficiency in children due to chronic accidental overdose of paracetamol (acetaminophen)

    NARCIS (Netherlands)

    Hameleers-Snijders, P.; Hogeveen, M.; Smeitink, J.A.M.; Kramers, C.; Draaisma, J.M.T.

    2007-01-01

    Two girls aged 4 and 3 years, respectively, experienced acute liver failure due to accidental ingestion of supratherapeutic doses of paracetamol (90 mg/kg/day or more). Recognition of chronic paracetamol intoxication as a cause of acute hepatic failure is often delayed. It is important to consider t

  15. La configuraci??n jur??dica del accidente de trabajo

    OpenAIRE

    S??nchez P??rez, Jos??

    2013-01-01

    Esta obra incorpora un an??lisis global del accidente de trabajo y su configuraci??n jur??dica. Analiza su evoluci??n hist??rica e incorpora una selecci??n de m??s de 300 sentencias del Tribunal Supremo que permiten identificar su contenido.

  16. Risky behavior, personality traits and road accidents among university students Comportamiento de riesgo, rasgos de personalidad y accidentes de carretera en estudiantes universitarios.

    Directory of Open Access Journals (Sweden)

    Aristides I. Ferreira

    2009-06-01

    Full Text Available The personality traits that mediate risky driving and accidents among university students drivers were investigated. Study 1 (N=132 tested for the relation between risky behaviors and personality (16PF-5 second order dimensions. Three factors were extracted concerning risky driving: driving errors of commission, distraction, and driving errors of omission. Individuals with low self-control and high levels of anxiety were more prone to commit distractive behavior and driving errors of omission. Low self-control and high independence levels were associated with driving errors of commission. In study 2 (N=540, we tested if the number of road accidents for which an individual has been responsible was related to risky driving behavior. Drivers who committed more accidents presented higher scores in three new risky driving factors obtained: reckless driving, impaired concentration and division of attention.

    Key words: Risky driving, personality, accidents, behavior.
    En este estudio se investigaron los rasgos de personalidad relacionados con la conducción de riesgo y los accidentes en estudiantes universitarios. El primer estudio (N=132 evaluó la relación entre los comportamientos de riesgo y la personalidad (16PF-5 dimensiones de segundo orden. Tres factores fueron extraídos en relación con la conducción de riesgo: cometer errores de conducción, distracción, errores de omisión en la conducción. Los individuos con bajo autocontrol y altos niveles de ansiedad eran más propensos a tener comportamientos distractores y cometer errores de omisión en la conducción. Mientras que sujetos con bajo autocontrol y altos niveles de independencia se asociaron con el factor cometer errores de conducción. En el segundo estudio (N=540 evaluamos si el número de accidentes de tráfico, de los que una persona ha sido responsable, está relacionado con el comportamiento de riesgo en la conducción. Los resultados muestran que los conductores

  17. Epidemiological analysis of individuals exposed to rabies in Fangshan District of Beijing from 2007 to 2010%北京市房山区2007~2010年狂犬病暴露者流行病学分析

    Institute of Scientific and Technical Information of China (English)

    周伟; 于海柱; 孟毅; 高美丽

    2011-01-01

    Objective To investigate the epidemiological characteristics of individuals exposed to rabies in Fangshan District of Beijing and provide a scientific basis for prevention. Methods The data of subjects exposed to rabies in Fangshan District in Beijing from January 2007 to December 2010 were statistically analyzed. Results A total of 57 698 cases exposed to rabies were registered in the vaccination clinic for rabies during this period. None of them developed rabies. The ratio of males to females was 1. 28:1. Young and middle - aged were the bulk of the exposed population. The majority of the victims were workers and peasants. Months of high exposure were May to August, accounting for 54.76% of the cases. Lower limbs were most vulnerable to exposure, making up 48. 54% . The attacking animals were mostly dogs and cats. 94. 98% of the animals were domestic. The immune history of 81. 18% of the animals was blank or unknown. 83. 10% of the patients saw a doctor within 24 hours. The rate of using passive immunization preparations was 23. 12% . Of five rabies cases, three cases treated the wound by themselves, and the others took no measures. Conclusions Popularizing knowledge on prevention of rabies, proper treatment of the wound, and inoculation are effective measures after exposure to rabies.%目的 总结北京市房山区狂犬病暴露者流行病学特征,为制定有效的预防措施提供科学依据.方法 对北京市房山区2007-01至2010-12狂犬病暴露者资料进行统计分析.结果 2007-01至2010-12房山区狂犬病免疫预防门诊共接诊狂犬病暴露者57 698例,无一例发病.男女性别比为1.28:1;以中青年为主;职业分布以工人、农民居多;暴露时间以5~9月份为高发月份,占54.76%;暴露部位以下肢多见,占48.54 %;致伤动物以犬和猫为主,94.98%为家养;81.18%无免疫史或免疫史不详;暴露者24 h就诊率为83.10%;被动免疫制剂使用率为23.12%.5例人狂犬病病例均未就诊,除3例对

  18. Collective individualism

    DEFF Research Database (Denmark)

    Baarts, Charlotte

    2009-01-01

    and expose workmates to. Aspects such as self-regulation, self-confidence and independence are acceptable values only to the extent that they do not pose a threat to the solidarity of the community or safety of other workers. The informal practice of safety is a tight-rope act that involves balancing...

  19. Preliminary study of internal monitoring of the occupational exposed individuals to the {sup 18}FDG at the C RCN-Ne, Recipe, Pernambuco, Brazil; Estudo preliminar de monitoracao interna dos individuos ocupacionalmente expostos ao {sup 18}FDG no CRCN-NE

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Cassio M., E-mail: cmo@cdtn.b [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil); Lacerda, Isabelle V.B.; Lima, Fabiana F.; Oliveira, Mercia L., E-mail: fflima@cnen.gov.b, E-mail: mercial@cnen.gov.b, E-mail: falima@cnen.gov.b [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil); Silva, Tania V. da; Alonso, Thessa C.; Silva, Teogenes A. da, E-mail: fflima@cnen.gov.b, E-mail: mercial@cnen.gov.b, E-mail: falima@cnen.gov.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2011-07-01

    This work aims to develop and establish a methodology for in vivo internal monitoring at individuals occupationally exposed (IOE) to F-18 in form of F-18DG at the DIPRA/CRCN-NE. The detection system used was the NaI(Tl) 3' x 3', coupled with the software Genie 2000. The measurements performed with the brain phantom were used to obtain the Calibration Factor. The bioassay data interpretation was performed through software AIDE, using the F-18DG biokinetic model available in ICRP 53 publication. The MDED obtained was compared to the value of the recording level, 1 mSv, recommended by IAEA in order to validate the technique. During two days of F-18DG productions, there were performed in vivo measurements of the IOE at DIPRA/CRCN-NE. The methodology developed demonstrated sufficient sensitivity for detect MDED of 76 n Sv. The results of the in vivo measurements demonstrated that all IOE from CRCN/NE obtained doses below MDED. (author)

  20. Control for occupationally exposed personnels

    Energy Technology Data Exchange (ETDEWEB)

    Murakami, Hiroyuki [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Momose, Takuma

    1999-03-01

    The present status of the technology for the measurement of personnel exposure dose was reviewed based on the basic concept of ICRP Recommendation on new assessment of exposure dose. The personnel dosimeter which has been mostly used by occupationally exposed personnels in Japan is film badge or thermoluminescence dosimeter. Now, photoluminescent glass dosimeter has been paid attention because pulse excitation method by UV laser has been developed. Measurement at an accuracy of 0.1 mSv or more became possible by using this dosimeter at present. In addition, characteristic studies for practical application of electronic, photostimulated luminescence and neutron dosimeters are progressing now. Revision of kinetic model of in vivo metabolism of radioactive substances is progressing based on the recent findings since ICRP Recommendation in 1990. Monitoring an individual internal exposure is made by two methods; direct measurement of the radiation emitted from the body and indirect one by radioanalysis of excretes etc. The latter is inferior to the former in respect of the accuracy of dose assessment, but the direct method is more suitable to detect a little amount of radioactive substance incorporated because of its high sensitivity. In future, it is needed to provide a considerable number of whole body counters against a large-scale nuclear accident. (M.N.)

  1. The use of unstable chromosome aberrations and micronuclei in the individual biomonitoring: a comparative study; Emprego das aberracoes cromossomicas instaveis e micronucleos no biomonitoramento individual: estudo comparativo

    Energy Technology Data Exchange (ETDEWEB)

    Fernandes, Thiago de Salazar e

    2005-02-15

    Biodosimetry is based on the investigation of radioinduced biological effects in order to correlate them with the absorbed dose. The quantification of unstable chromosome aberrations and micronuclei, in peripheral blood lymphocytes, are two methods commonly used in biodosimetry. In this context, the aim of this research was to compare these methods in the biomonitoring of health care professionals occupationally exposed to ionizing radiation. In parallel, the technique of C-banding was evaluated for quality control of unstable chromosome aberrations analyses. Thus, samples of peripheral blood from health care professionals of three hospitals from Recife (Brazil) were collected, and the lymphocytes cultures were carried out based on the cytogenetic classical technique. It was pointed out that analysis of micronuclei is faster than the unstable chromosome aberrations ones, which suggests the use of the former in preliminary evaluation in cases of suspected accidental exposure. C-banding technique was efficient, as confirmatory test, in the identification of dicentrics and rings during the analyses of unstable chromosome aberrations, being able to be applied in the quality control in biodosimetry. The comparison between the individual work conditions with the frequencies of unstable aberrations and micronuclei obtained from cytogenetic analysis, resulted in the change of behavior of the professionals involved in this research, with a better observance of the radioprotection standards. (author)

  2. Individual Education.

    Science.gov (United States)

    Corsini, Raymond

    1981-01-01

    Paper presented at the 66th Convention of the International Association of Pupil Personnel Workers, October 20, 1980, Baltimore, Maryland, describes individual education based on the principles of Alfred Adler. Defines six advantages of individual education, emphasizing student responsibility, mutual respect, and allowing students to progress at…

  3. Interphase cytogenetics of workers exposed to benzene

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, L.; Wang, Yunxia; Venkatesh, P. [Univ. of California, Berkeley, CA (United States)] [and others

    1996-12-01

    Fluorescence in situ hybridization (FISH) is a powerful new technique that allows numerical chromosome aberrations (aneuploidy) to be detected in interphase cells. In previous studies, FISH has been used to demonstrate that the benzene metabolites hydroquinone and 1,2,4-benzenetriol induce aneuploidy of chromosomes 7 and 9 in cultures of human cells. In the present study, we used an interphase FISH procedure to perform cytogenetic analyses on the blood cells of 43 workers exposed to benzene (median=31 ppm, 8-hr time-weighted average) and 44 matched controls from Shanghai, China. High benzene exposure (>31 ppm, n=22) increased the hyperdiploid frequency of chromosome 9 (p<0.01), but lower exposure (<31 ppm, n=21) did not. Trisomy 9 was the major form of benzene-induced hyperdiploidy. The level of hyperdiploidy in exposed workers correlated with their urinary phenol level (r= 0.58, p < 0.0001), a measure of internal benzene close. A significant correlation was also found between hyperdiploicly and decreased absolute lymphocyte count, an indicator of benzene hematotoxicity, in the exposed group (r=-0.44, p=0.003) but not in controls (r=-0.09, P=0.58). These results show that high benzene exposure induces aneuploidy of chromosome 9 in nondiseased individuals, with trisomy being the most prevalent form. They further highlight the usefulness of interphase cytogenetics and FISH for the rapid and sensitive detection of aneuploidy in exposed human populations. 35 refs., 3 figs., 2 tabs.

  4. Multifocal inflammatory leukoencephalopathy induced by accidental consumption of levamisole: A case report.

    Science.gov (United States)

    Sariaslani, Payam; Ghanbari, Ali; Ghanbari, Parvin

    2012-01-01

    Levamisole is an anthelmintic agent and also immunostimulant drug which is used to treat colorectal cancer. The present study aimed to show accidental consumption of levamisole alone induced multifocal inflammatory leukoencephalopathy. A 53-year-old male was admitted to the Neurology Department of Farabi Hospital (Kermanshah, Iran) with walking inability and recognition disorder. Following clinical examinations, the patient diagnosed as multifocal inflammatory leukoencephalopathy following levamisole consumption.The patient was treated with intravenous methylprednisolone followed by prednisolone. The magnetic resonance imaging (MRI) was done 1 month later and did not show a reduction or remission in the lesions. History of the patient showed that he had accidentally consumed levamisole 8 months ago. It seems that the consumption of levamisole can induce multifocal inflammatory leukoencephalopathy and delayed treatment of the patient with corticosteroid cannot diminish the neurotoxicity of levamisole. In addition, the cytotoxic dose of levamisole induces irreversible multifocal inflammatory leukoencephalopathy.

  5. Accidental Displacement of Third Molar into the Sublingual Space: a Case Report

    Directory of Open Access Journals (Sweden)

    Rubens Jorge

    2014-10-01

    Full Text Available Background: Successful extraction of third molars depends on preoperative diagnosis and planning. Gold standard preoperative examinations are performed through computed tomography, decreasing risks and avoiding potential accidents. The present report highlights the value of preoperative examinations in face of accidentally displaced third molars. Methods: An 18-years-old female patient underwent a third mandibular molar extraction with a general dentist. Accidentally, the mandibular left third molar was displaced into the sublingual space, making necessary a second surgical step. The surgery was interrupted and the patient was referred to an expert in maxillofacial surgery. Results: After 21 days awaiting an asymptomatic health status, the second surgical step was successfully performed using multislice computed tomography as preoperative imaging guide. Conclusions: The present case report highlights the clinical usefulness of imaging planning and informed consents in face of legal and ethic potential complaints.

  6. Marine oil spill risk mapping for accidental pollution and its application in a coastal city.

    Science.gov (United States)

    Lan, Dongdong; Liang, Bin; Bao, Chenguang; Ma, Minghui; Xu, Yan; Yu, Chunyan

    2015-07-15

    Accidental marine oil spill pollution can result in severe environmental, ecological, economic and other consequences. This paper discussed the model of Marine Oil Spill Risk Mapping (MOSRM), which was constructed as follows: (1) proposing a marine oil spill risk system based on the typical marine oil spill pollution accidents and prevailing risk theories; (2) identifying suitable indexes that are supported by quantitative sub-indexes; (3) constructing the risk measuring models according to the actual interactions between the factors in the risk system; and (4) assessing marine oil spill risk on coastal city scale with GIS to map the overall risk. The case study of accidental marine oil spill pollution in the coastal area of Dalian, China was used to demonstrate the effectiveness of the model. The coastal areas of Dalian were divided into three zones with risk degrees of high, medium, and low. And detailed countermeasures were proposed for specific risk zones.

  7. A Precise Analytic Delayed Coincidence Efficiency and Accidental Coincidence Rate Calculation

    CERN Document Server

    Yu, Jingyi; Chen, Shaomin

    2013-01-01

    In a delayed coincidence experiment, for example, the recent reactor neutrino oscillation experiments, a precise analytic determination of the delayed coincidence signal efficiency and the accidental coincidence background rate is important for the high accuracy measurement of the oscillation parameters and to understand systematic uncertainties associated with fluctuations in muon rate and random background rate. In this work, a data model is proposed to describe the full time sequence of all possible events on the live time axis. The acceptance of delayed coincidence signals, the rate of accidental backgrounds and other coincidence possibilities are calculated by assuming that all of the `net muons' are uniformly distributed on the live time axis. The intrinsic relative uncertainties in the event rates are at the $10^{-5}$ level for all combinations. The model and predictions are verified with a high statistics Monte Carlo study with a set of realistic parameters.

  8. [The prevalence of accidental poisoning in a hospital pediatric unit of Latium].

    Science.gov (United States)

    Faraoni, F; Protano, C; Bini, V; Lizzi, R

    2006-01-01

    The aim of this study was to investigate the trend of accidental poisoning among children, over a period of fifteen years, from 1990 to 2004, in the pediatric wards of a hospital in Latium (Italy). The prevalence of childhood poisoning was calculated based on the medical records of the pediatric unit of the hospital. The derived data was divided into different categories according to age, gender and types of poisoning. The results of this study show a decrease in accidental pediatric poisoning; according to the literature the frequency of poisoning was higher in males, under the age of 2 years, than females. Trends show an increase in pharmaceutical poisonings. The present study underlines the need for continuous information on prevention and educational programs organized by the Institutions, territorial sanitary services and GP with the aim of increasing the awareness of parents regarding the risk factors of poisoning.

  9. Accidental versus operational oil spills from shipping in the Baltic Sea: risk governance and management strategies.

    Science.gov (United States)

    Hassler, Björn

    2011-03-01

    Marine governance of oil transportation is complex. Due to difficulties in effectively monitoring procedures on vessels en voyage, incentives to save costs by not following established regulations on issues such as cleaning of tanks, crew size, and safe navigation may be substantial. The issue of problem structure is placed in focus, that is, to what degree the specific characteristics and complexity of intentional versus accidental oil spill risks affect institutional responses. It is shown that whereas the risk of accidental oil spills primarily has been met by technical requirements on the vessels in combination with Port State control, attempts have been made to curb intentional pollution by for example increased surveillance and smart governance mechanisms such as the No-Special-Fee system. It is suggested that environmental safety could be improved by increased use of smart governance mechanisms tightly adapted to key actors' incentives to alter behavior in preferable directions.

  10. Multifocal Inflammatory Leukoencephalopathy Induced by Accidental Consumption of Levamisole: A Case Report

    Directory of Open Access Journals (Sweden)

    Ali Ghanbari

    2012-01-01

    Full Text Available Levamisole is an anthelmintic agent and also immunostimulant drug which is used to treat colorectal cancer. The present study aimed to show accidental consumption of levamisole alone induced multifocalinflammatory leukoencephalopathy. A 53-year-old male was admitted to the Neurology Department of Farabi Hospital(Kermanshah, Iran with walking inability and recognition disorder. Following clinical examinations, the patient diagnosed as multifocal inflammatory leukoencephalopathy following levamisole consumption.The patient was treated with intravenous methylprednisolone followed by prednisolone. The magnetic resonance imaging (MRI was done 1 month later and did not show a reduction or remission in the lesions. History of the patient showed that he had accidentally consumed levamisole 8 months ago. It seems that the consumption of levamisole can induce multifocal inflammatory leukoencephalopathy and delayed treatment of the patient with corticosteroid cannot diminish the neurotoxicity of levamisole. In addition, the cytotoxic dose of levamisole induces irreversible multifocal inflammatory leukoencephalopathy.

  11. Multifocal inflammatory leukoencephalopathy induced by accidental consumption of levamisole: A case report

    Science.gov (United States)

    Sariaslani, Payam; Ghanbari, Parvin

    2012-01-01

    Levamisole is an anthelmintic agent and also immunostimulant drug which is used to treat colorectal cancer. The present study aimed to show accidental consumption of levamisole alone induced multifocal inflammatory leukoencephalopathy. A 53-year-old male was admitted to the Neurology Department of Farabi Hospital (Kermanshah, Iran) with walking inability and recognition disorder. Following clinical examinations, the patient diagnosed as multifocal inflammatory leukoencephalopathy following levamisole consumption.The patient was treated with intravenous methylprednisolone followed by prednisolone. The magnetic resonance imaging (MRI) was done 1 month later and did not show a reduction or remission in the lesions. History of the patient showed that he had accidentally consumed levamisole 8 months ago. It seems that the consumption of levamisole can induce multifocal inflammatory leukoencephalopathy and delayed treatment of the patient with corticosteroid cannot diminish the neurotoxicity of levamisole. In addition, the cytotoxic dose of levamisole induces irreversible multifocal inflammatory leukoencephalopathy. PMID:24250864

  12. Salade malade: malignant ventricular arrhythmias due to an accidental intoxication with Aconitum napellus

    OpenAIRE

    Weijters, B.J.; Verbunt, R.J.A.M.; Hoogsteen, J.; Visser, R.F.

    2008-01-01

    Intoxication with Aconitum napellus is rare in our regions. Aconite alkaloids can cause ventricular arrhythmia by a prolonged activation of sodium channels. Because the margin of safety is low between the analgesic and toxic dose, intoxication is not rare when Aconite is used in herbal medicine. We present a case in which a 39-year-old male was accidentally intoxicated with Aconite. Even though no antidote or adequate therapy is available he was successfully resuscitated. (Neth Heart J 2008;1...

  13. Current controversies in the interpretation of non-accidental head injury

    Energy Technology Data Exchange (ETDEWEB)

    Jaspan, Tim [Imaging Centre, University Hospital, Nottingham (United Kingdom)

    2008-06-15

    The field of non-accidental injury (NAI) has been the subject of a number of theories and hypotheses of variable merit. Concerning injuries that occur within the intracranial compartment, much research has been undertaken to investigate the cause of SDH and parenchymal brain injury. Much, however, remains contentious, particularly regarding the medicolegal aspects of suspected child abuse. Issues that present the greatest challenges will be addressed. (orig.)

  14. Artritis tuberculosa - Autoinoculación en profesional sanitario por accidente laboral

    Directory of Open Access Journals (Sweden)

    Sara Cardoso

    2012-12-01

    Los autores describen un caso de monoartritis tuberculosa en un médico traumatólogo previamente sano, por inoculación accidental durante el drenaje quirúrgico de una artritis séptica. El tratamiento oral con fármacos antituberculosos y el drenaje quirúrgico fueron suficientes, sin tener que recurrir a la sinovectomía.

  15. The Impacts of Air Temperature on Accidental Casualties in Beijing, China

    Science.gov (United States)

    Ma, Pan; Wang, Shigong; Fan, Xingang; Li, Tanshi

    2016-01-01

    Emergency room (ER) visits for accidental casualties, according to the International Classification of Deceases 10th Revision Chapters 19 and 20, include injury, poisoning, and external causes (IPEC). Annual distribution of 187,008 ER visits that took place between 2009 and 2011 in Beijing, China displayed regularity rather than random characteristics. The annual cycle from the Fourier series fitting of the number of ER visits was found to explain 63.2% of its total variance. In this study, the possible effect and regulation of meteorological conditions on these ER visits are investigated through the use of correlation analysis, as well as statistical modeling by using the Distributed Lag Non-linear Model and Generalized Additive Model. Correlation analysis indicated that meteorological variables that positively correlated with temperature have a positive relationship with the number of ER visits, and vice versa. The temperature metrics of maximum, minimum, and mean temperatures were found to have similar overall impacts, including both the direct impact on human mental/physical conditions and indirect impact on human behavior. The lag analysis indicated that the overall impacts of temperatures higher than the 50th percentile on ER visits occur immediately, whereas low temperatures show protective effects in the first few days. Accidental casualties happen more frequently on warm days when the mean temperature is higher than 14 °C than on cold days. Mean temperatures of around 26 °C result in the greatest possibility of ER visits for accidental casualties. In addition, males were found to face a higher risk of accidental casualties than females at high temperatures. Therefore, the IPEC-classified ER visits are not pure accidents; instead, they are associated closely with meteorological conditions, especially temperature. PMID:27827842

  16. The Impacts of Air Temperature on Accidental Casualties in Beijing, China

    Directory of Open Access Journals (Sweden)

    Pan Ma

    2016-11-01

    Full Text Available Emergency room (ER visits for accidental casualties, according to the International Classification of Deceases 10th Revision Chapters 19 and 20, include injury, poisoning, and external causes (IPEC. Annual distribution of 187,008 ER visits that took place between 2009 and 2011 in Beijing, China displayed regularity rather than random characteristics. The annual cycle from the Fourier series fitting of the number of ER visits was found to explain 63.2% of its total variance. In this study, the possible effect and regulation of meteorological conditions on these ER visits are investigated through the use of correlation analysis, as well as statistical modeling by using the Distributed Lag Non-linear Model and Generalized Additive Model. Correlation analysis indicated that meteorological variables that positively correlated with temperature have a positive relationship with the number of ER visits, and vice versa. The temperature metrics of maximum, minimum, and mean temperatures were found to have similar overall impacts, including both the direct impact on human mental/physical conditions and indirect impact on human behavior. The lag analysis indicated that the overall impacts of temperatures higher than the 50th percentile on ER visits occur immediately, whereas low temperatures show protective effects in the first few days. Accidental casualties happen more frequently on warm days when the mean temperature is higher than 14 °C than on cold days. Mean temperatures of around 26 °C result in the greatest possibility of ER visits for accidental casualties. In addition, males were found to face a higher risk of accidental casualties than females at high temperatures. Therefore, the IPEC-classified ER visits are not pure accidents; instead, they are associated closely with meteorological conditions, especially temperature.

  17. Analizan partículas calientes del accidente nuclear de Palomares

    OpenAIRE

    2012-01-01

    Investigadores pertenecientes al Centro Nacional de Aceleradores, CNA, (Universidad de Sevilla-Junta de Andalucía-CSIC) en colaboración con la Organización Internacional de la Energía Atómica (IAEA), han llevado a cabo me didas de elementos transuránicos en partículas calientes procedentes de accidentes nucleares tales como el de Thule (Groenlandia) o Palomares (España).

  18. Cuidado popular de familias con un adulto mayor sobreviviente del primer accidente cerebrovascular

    OpenAIRE

    Lucero López-Díaz; Fabiola Castellanos-Soriano; Esperanza Muñoz-Torres

    2016-01-01

    Introducción: el accidente cerebrovascular afecta a numerosas personas en el mundo y se constituye en la principal causa de muer- te. Los sobrevivientes pueden padecer discapacidad y sufrir modificaciones en las actividades cotidianas. La familia es el principal apoyo del sobreviviente y al ser parte de una misma cultura, construye acciones de cuidado en búsqueda del bienestar. Objetivo: describir las acciones del cuidado popular de las familias con un adulto mayor sobreviviente del prim...

  19. Los accidentes laborales, su impacto económico y social

    Directory of Open Access Journals (Sweden)

    Miguel Antonio Cisneros-Prieto

    2015-01-01

    Full Text Available Este artículo investigativo aborda la problemática de los accidentes de trabajo en las empresas estatales en la provincia Holguín y la importancia de la determinación efectiva de las causas que los provocan, a partir del análisis del comportamiento de los indicadores emitidos por la Oficina Nacional de Estadística e Información (ONEI hasta el año 2014. Se analiza el comportamiento, en el período comprendido entre el 2011-2014, de las cifras de trabajadores lesionados y fallecidos, y se evalúa el impacto humano, económico y social de la accidentalidad en las empresas y la sociedad. Se demuestra un incremento en el indicador “Días perdidos por accidentados”, siendo la principal lectura de este comportamiento el aumento de la gravedad de los accidentes de trabajo, este es un elemento que generalmente las organizaciones no valoran en su verdadera magnitud como un significativo impacto negativo de su eficiencia económica y financiera. Se presenta un enfoque sobre las potencialidades de la comunicación en función de la solución o atenuación de la ocurrencia de los accidentes y en consecuencia ladisminución del costo financiero y social de esta compleja problemática.

  20. Decay Heat Removal and Transient Analysis in Accidental Conditions in the EFIT Reactor

    Directory of Open Access Journals (Sweden)

    Giacomino Bandini

    2008-01-01

    Full Text Available The development of a conceptual design of an industrial-scale transmutation facility (EFIT of several 100 MW thermal power based on accelerator-driven system (ADS is addressed in the frame of the European EUROTRANS Integral Project. In normal operation, the core power of EFIT reactor is removed through steam generators by four secondary loops fed by water. A safety-related decay heat removal (DHR system provided with four independent inherently safe loops is installed in the primary vessel to remove the decay heat by natural convection circulation under accidental conditions which are caused by a loss-of-heat sink (LOHS. In order to confirm the adequacy of the adopted solution for decay heat removal in accidental conditions, some multi-D analyses have been carried out with the SIMMER-III code. The results of the SIMMER-III code have been then used to support the RELAP5 1D representation of the natural circulation flow paths in the reactor vessel. Finally, the thermal-hydraulic RELAP5 code has been employed for the analysis of LOHS accidental scenarios.

  1. Humeral fracture in non-ambulant infants - a possible accidental mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Somers, John M.; Halliday, Katharine E. [Nottingham University Hospitals, Radiology Department, Nottingham (United Kingdom); Chapman, Stephen [Birmingham Children' s Hospital, Birmingham (United Kingdom)

    2014-10-15

    Humeral fracture in a non-ambulant infant younger than 1 year is suspicious for a non-accidental injury unless there is a credible accidental explanation. A previously unrecognised accidental mechanism was described in 1996 whereby a 5-month-old infant was rolled by a 3-year-old sibling from a prone to a supine position. To investigate the widely accepted view that an infant with limited mobility cannot sustain a fracture of the humerus by his or her own actions in the absence of the intervention of an external party. We present seven cases of non-ambulant infants between 4 and 7 months of age in whom an isolated humeral fracture was the only injury present. In each case the caregiver described the fracture occurring when the child rolled over, trapping the dependent arm, without the intervention of another party. There is no proof for this mechanism in the form of an independent witness or video recording. However, we propose that this mechanism is worthy of further consideration as a rare and unusual cause for the injury. Further study is required. (orig.)

  2. Mortalidad por accidentes de tránsito en Bayamo, Cuba 2011

    Directory of Open Access Journals (Sweden)

    Arlines Piña-Tornés

    Full Text Available Con el objetivo de describir la mortalidad por accidentes de tránsito en Bayamo, Cuba, en el año 2011 se realizó una revisión de los pacientes lesionados y fallecidos a causa de accidentes de tránsito, registrados en Hospital Carlos M. de Céspedes. Se atendieron en emergencias 1365 lesionados, predominando el grupo etario de 25 a 44 años con 372 pacientes (27,3%, y el sexo masculino con 1071 (78,5%. Fallecieron 46 personas, en su mayoría del mismo grupo de edad y de sexo masculino. Los traumatismos múltiples (52,6% y cráneofaciales (34,2% fueron las localizaciones predominantes. Se destacaron los atropellos por vehículo de motor con mortalidad del 26,3%. En conclusión, la mortalidad por accidentes de tránsito predomina en adultos jóvenes masculinos; cuyas consecuencias fatales son debido a traumatismos múltiples por atropellos.

  3. Cuidado popular de familias con un adulto mayor sobreviviente del primer accidente cerebrovascular

    Directory of Open Access Journals (Sweden)

    Lucero López-Díaz

    2016-01-01

    Full Text Available Introducción: el accidente cerebrovascular afecta a numerosas personas en el mundo y se constituye en la principal causa de muer- te. Los sobrevivientes pueden padecer discapacidad y sufrir modificaciones en las actividades cotidianas. La familia es el principal apoyo del sobreviviente y al ser parte de una misma cultura, construye acciones de cuidado en búsqueda del bienestar. Objetivo: describir las acciones del cuidado popular de las familias con un adulto mayor sobreviviente del primer accidente cerebrovascular. Método: estudio etnográfico, con observación participante y entrevistas en profundidad. Participaron siete familias bogotanas (siete adultos mayores entre los dos y diez meses posteriores al primer accidente cerebrovascular y los siete cuidadores principales respectivos. Resultados: cuidadores y adulto mayor comparten acciones de cuidado para la recuperación, relacionadas con la alimentación, el cuidado personal y la ingesta de medicamentos permeadas por la creencia religiosa, fuente de soporte y vínculo afectivo. Conclusión: conocer el cuidado popular de esta población posibilita proponer acciones culturalmente congruentes con sus valores y creencias para potencializar las ca- pacidades familiares e intermediar en los procesos de tratamiento.

  4. Mortalidad por accidentes de tránsito en Bayamo, Cuba 2011

    Directory of Open Access Journals (Sweden)

    Arlines Piña-Tornés

    2014-10-01

    Full Text Available Con el objetivo de describir la mortalidad por accidentes de tránsito en Bayamo, Cuba, en el año 2011 se realizó una revisión de los pacientes lesionados y fallecidos a causa de accidentes de tránsito, registrados en Hospital Carlos M. de Céspedes. Se atendieron en emergencias 1365 lesionados, predominando el grupo etario de 25 a 44 años con 372 pacientes (27,3%, y el sexo masculino con 1071 (78,5%. Fallecieron 46 personas, en su mayoría del mismo grupo de edad y de sexo masculino. Los traumatismos múltiples (52,6% y cráneofaciales (34,2% fueron las localizaciones predominantes. Se destacaron los atropellos por vehículo de motor con mortalidad del 26,3%. En conclusión, la mortalidad por accidentes de tránsito predomina en adultos jóvenes masculinos; cuyas consecuencias fatales son debido a traumatismos múltiples por atropellos.

  5. Accidental Coverage of Both Renal Arteries during Infrarenal Aortic Stent-Graft Implantation: Cause and Treatment

    Directory of Open Access Journals (Sweden)

    Umberto Marcello Bracale

    2014-01-01

    Full Text Available The purpose of this paper is to report a salvage maneuver for accidental coverage of both renal arteries during endovascular aneurysm repair (EVAR of an infrarenal abdominal aortic aneurysm (AAA. A 72-year-old female with a 6 cm infrarenal abdominal aortic aneurysm was treated by endovascular means with a standard bifurcated graft. Upon completing an angiogram, both renal arteries were found to be accidentally occluded. Through a left percutaneous brachial approach, the right renal artery was catheterized and a chimney stent was deployed; however this was not possible for the left renal artery. A retroperitoneal surgical approach was therefore carried out with a retrograde chimney stent implanted to restore blood flow. After three months, both renal arteries were patent and renal function was not different from the baseline. Both endovascular with percutaneous access via the brachial artery and open retroperitoneal approaches with retrograde catheterization are feasible rescue techniques to recanalize the accidentally occluded renal arteries during EVAR.

  6. Fallopian tube insertion into the uterine cavity discovered accidentally during laparoscopic retrieval of a misplaced coil from the pelvic cavity

    OpenAIRE

    Panayotidis, Costas; Foidart, Jean-Michel; Nisolle, Michelle

    2008-01-01

    This article presents for the first time in the literature a case of fallopian tube insertion into the uterine cavity discovered accidentally during laparoscopic retrieval of a misplaced coil from the pelvic cavity. Peer reviewed

  7. An atypical case of successful resuscitation of an accidental profound hypothermia patient, occurring in a temperate climate.

    LENUS (Irish Health Repository)

    Coleman, E

    2010-03-01

    Cases of accidental profound hypothermia occur most frequently in cold, northern climates. We describe an atypical case, occurring in a temperate climate, where a hypothermic cardiac-arrested patient was successfully resuscitated using extracorporeal circulation (ECC).

  8. Perfil audiométrico de indivíduos expostos ao ruído atendidos no núcleo de saúde ocupacional de um hospital do município de Montes Claros, Minas Gerais Audiometric profile of individuals exposed to noise attended at the center for occupational health for a hospital in the municipality of Montes Claros, Minas Gerais

    Directory of Open Access Journals (Sweden)

    Rejane Noronha Leão

    2010-04-01

    Full Text Available OBJETIVO: traçar o perfil audiométrico de pacientes expostos a ruído, atendidos no Núcleo de Saúde Ocupacional da Fundação Hospitalar de Montes Claros (Hospital Aroldo Tourinho em Minas Gerais. MÉTODOS: análise de prontuários audiológicos do Núcleo de Saúde Ocupacional da Fundação Hospitalar de Montes Claros/MG de trabalhadores expostos a ruído ocupacional no período de junho a dezembro de 2006. RESULTADOS: a amostra de prontuários caracterizou-se por predominância do sexo masculino (98,3%, com média de 34,7 anos idade. Dos dados obtidos: 37,9% dos trabalhadores não usavam nenhum tipo de protetor auditivo; 19,8% dos trabalhadores foram expostos a um ou mais agente químico; 17% descreveram alguma queixa auditiva; 6,3% usavam algum medicamento; 7,4% citaram doenças prévias; 6,7% relataram deficientes auditivos na família. Identificou-se que 13,2% dos trabalhadores apresentaram perda auditiva na orelha direita (31,8% destas perdas auditivas foram sugestivas de perda auditiva induzida por níveis elevados de pressão sonora e 15,5% na orelha esquerda (36,77% destas perdas auditivas foram sugestivas de perda auditiva induzida por níveis elevados de pressão sonora. CONCLUSÃO: nesta pesquisa houve uma alta prevalência de alterações audiométricas sugestivas de perda auditiva induzida por níveis elevados de pressão sonora, com predomínio maior de perdas auditivas na orelha esquerda. Também houve diferenças significantes em relação à exposição diária dos trabalhadores ao ruído, ao ruído extra-ocupacional e às funções desempenhadas pelos trabalhadores. Além disso, é preocupante o uso insuficiente e inadequado do equipamento de proteção individual auricular por parte dos trabalhadores expostos ao ruído.PURPOSE: to draw the audiometric profile of patients exposed to noise, attended the Center for Occupational Health Foundation's Hospital of Montes Claros (Aroldo Tourinho Hospital in Minas Gerais. METHODS

  9. El subregistro de accidentes de trabajo en una Unidad de Medicina Familiar del Instituto Mexicano del Seguro Social. Subregistro de accidentes de trabajo en asegurados

    Directory of Open Access Journals (Sweden)

    Patricia Pérez Martínez

    2008-09-01

    Full Text Available Objetivo: Determinar el subregistro de los accidentes de trabajo en una Unidad de Medicina Familiar (UMFX escogida, inicialmente atendidos en el servicio de urgencias de un Hospital General de Zona (HGZ, del Instituto Mexicano del Seguro Social (IMSS en el año 2002. Material y métodos: Es un estudio transversal que utilizó información de la fuente original del HGZ que otorga la primera atención médica. Se elaboró una cédula de registro con las diversas fuentes de información, efectuando confrontación, seguimiento y análisis estadístico de las mismas. Resultados: De 6551 probables accidentes de trabajo atendidos en el HGZ, se seleccionaron 821 casos adscritos a la UMFX escogida. Se conformaron tres grupos de acuerdo con su dictamen: Grupo I= SÍ de trabajo, 35.4% (290; Grupo II=NO de trabajo, 4.6% (38, y el Grupo III= no calificados y atendidos en urgencias, 60%(493; este último representa el subregistro de los accidentes de trabajo. Conclusiones: El subregistro del 60% es de los más altos reportado en la literatura, lo cual representa para el IMSS, los trabajadores y el país graves repercusiones económicas y sociales no cuantificadas.Objective: To determine the Occupational Accidents Subregistry at a selected Family Medicine Unit (FMUX initially treated at a Mexican Institute of Social Security (IMSS General Zone Hospital (HGZ during the year 2002. Materials and Methods: This is a transversal study utilizing information from the original source, the HGZ primary-care hospital-facility. We elaborated a registry permit with diverse information sources, and conducted confrontation, followup, and statistical analysis of these sources. Results: Of 6,551 probable occupational accidents treated at the HGZ Emergency Room, we selected 821 cases ascribed to the selected FMUX. We made up three groups according these dictates: Group I = YES, occupational, 35.4% (290; Group II = NO, occupational, 4.6% (38, and Grupo III = not qualified and

  10. Bursitis por mercurio tras accidente laboral: a propósito de un caso Bursitis due to Mercury after a work accident: a case report

    Directory of Open Access Journals (Sweden)

    Susana Lastras González

    2010-06-01

    Full Text Available Auxiliar de enfermería de 28 años que acude al Servicio de Urgencias porque refiere dolor y dificultad para la movilización en rodilla derecha, tras accidente laboral, hace dos días. Refiere que se resbaló mientras transportaba 32 termómetros de mercurio, rompiéndose éstos sobre su rodilla, creando una pequeña herida, siendo la puerta de entrada del metal. En la radiografía, se objetiva el cuerpo extraño metálico, correspondiente a mercurio, en bursa rotuliana. Tras el diagnóstico, se realizó la extracción de la bursa, recuperándose la trabajadora totalmente tras la intervención. Con este caso clínico que aportamos, queremos conocer los efectos del mercurio en la salud de las personas expuestas a dicho metal, estudiar los errores acontecidos en este accidente laboral, valorando cuáles hubieran sido las medidas de actuación preventiva adecuadas para evitar la repetición de este tipo de accidentes y, por último, reflexionar acerca de la relación beneficio-riesgo del uso del mercurio en aparatos de medición en el ámbito sanitario.A 28-year-old woman, nursing assistant, who attends to emergency service, referring pain and difficulty mobilizing right knee after a work accident two days ago. She relates that slipped while carrying 32 mercury thermometers, breaking them on her knee, creating a small wound, being the gateway to the metal. In the radiograph, we objective a metallic foreign body, corresponding to mercury, in patellar bursa. After the diagnosis, the bursa was extracted, and the worker recovered completely, after surgery. With this case report we bring, we want to know the health effects of mercury in people exposed to this metal, studying the errors occurred in this accident, assessing measures of preventive action that would have been neccesary to preclude recurrence of this type accidents and, finally, think about the risk-benefit balance the use of mercury in measuring devices in healthcare.

  11. Individualizing Medicare.

    Science.gov (United States)

    Chollet, D J

    1999-05-01

    Despite the enactment of significant changes to the Medicare program in 1997, Medicare's Hospital Insurance trust fund is projected to be exhausted just as the baby boom enters retirement. To address Medicare's financial difficulties, a number of reform proposals have been offered, including several to individualize Medicare financing and benefits. These proposals would attempt to increase Medicare revenues and reduce Medicare expenditures by having individuals bear risk--investment market risk before retirement and insurance market risk after retirement. Many fundamental aspects of these proposals have yet to be worked out, including how to guarantee a baseline level of saving for health insurance after retirement, how retirees might finance unanticipated health insurance price increases after retirement, the potential implications for Medicaid of inadequate individual saving, and whether the administrative cost of making the system fair and adequate ultimately would eliminate any rate-of-return advantages from allowing workers to invest their Medicare contributions in corporate stocks and bonds.

  12. [Modifications of hepatic transaminases in workers exposed to low doses of isopropanol].

    Science.gov (United States)

    Iavicoli, I; Fontana, L; Iavicoli, S

    2007-01-01

    Isopropanol (IPA) is a volatile solvent that is used in many industrial process. The major symptoms of acute isopropanol toxicity include dizziness, incoordination, headache, hypothermia, eye ataxia, irritation of upper respiratory tract and shortness of breath. Vomiting, hematemesis, diarrhoea and hypotension may occur following accidental ingestion of IPA. No data regarding subchronic or chronic toxicity of IPA were identified. The aim of this study was to measure the serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and of gamma-glutamyltransferase (gamma-GT) of the last five years in 40 printer workers after the removal of IPA from the industry. The serum levels of ALT, AST and gamma-GT were higher in the exposed workers than in non exposed. In conclusion, the results of this study show that the removal of IPA from the industry had a positive health effect improving the hepatic function of the workers.

  13. Development of management tools for accidental radiological contamination of the French coastal areas - Development of management tools for accidental radiological contamination in the French marine coastal areas

    Energy Technology Data Exchange (ETDEWEB)

    Duffa, C.; Charmasson, S. [IRSN/PRP-ENV/SESURE/LERCM - Antenne de Radioecologie Marine, Centre Ifremer, Zone portuaire de Bregaillon, 13507 La Seyne sur Mer (France); Bailly du Bois, P.; Fievet, B. [IRSN/PRP-ENV/SERIS/LRC (France); Couvez, C.; Renaud, P. [IRSN/PRP-ENV/SESURE/DIR (France); Didier, D. [IRSN/PRP-CRI/SESUC/BMTA (France)

    2014-07-01

    The Fukushima nuclear accident led to the most important accidental release of artificial radionuclides into the sea. This accident has underlined the importance of being able to adequately reproduce the fate of radioactive releases and to estimate their consequences for the marine environment. For its Crisis Centre, the French Institute for Radioprotection and Nuclear Safety (IRSN) has operational tools, in order to help experts and decision makers in case of any atmospheric accidental release and terrestrial environment contamination. The on-going project aims to develop tools to manage any marine contamination of the French coastal areas. We should be able to evaluate and anticipate the marine post-accidental situation: contaminated areas localization and contamination levels, and possible consequences. Many sites has be considered as potential source terms into the sea: the Coastal Nuclear Power Plants, the La Hague reprocessing Plant, the Brest and Toulon Military Harbours as home-ports of nuclear powered vessels, and different river mouths (Rhone River, Gironde, Loire, Seine) that could be contaminated by upstream accidental release. To achieve this goal, two complementary approaches are developed: Marine sheets and a dedicated modelling tool (STERNE). - Marine sheets aim to summarize marine environment characteristics for the different sites, identify potential stakes for human protection such as aquaculture areas, beaches, or industrial water intakes, and ecological stakes. Whenever possible, a local climatology (main currents depending on meteorological or tide conditions) that could be a support to first environmental measurement strategy is proposed. A list of available local contacts for any operational management is also provided. - The modelling tool, STERNE (Simulation du Transport et du transfert d'Elements Radioactifs dans l'environNEment marin), must predict radionuclide dispersion and contamination of water, marine species and sediments

  14. 5th National Audit Project (NAP5) on accidental awareness during general anaesthesia: summary of main findings and risk factors.

    Science.gov (United States)

    Pandit, J J; Andrade, J; Bogod, D G; Hitchman, J M; Jonker, W R; Lucas, N; Mackay, J H; Nimmo, A F; O'Connor, K; O'Sullivan, E P; Paul, R G; Palmer, J H M G; Plaat, F; Radcliffe, J J; Sury, M R J; Torevell, H E; Wang, M; Hainsworth, J; Cook, T M

    2014-10-01

    We present the main findings of the 5th National Audit Project (NAP5) on accidental awareness during general anaesthesia (AAGA). Incidences were estimated using reports of accidental awareness as the numerator, and a parallel national anaesthetic activity survey to provide denominator data. The incidence of certain/probable and possible accidental awareness cases was ~1:19,600 anaesthetics (95% confidence interval 1:16,700-23,450). However, there was considerable variation across subtypes of techniques or subspecialities. The incidence with neuromuscular block (NMB) was ~1:8200 (1:7030-9700), and without, it was ~1:135,900 (1:78,600-299,000). The cases of AAGA reported to NAP5 were overwhelmingly cases of unintended awareness during NMB. The incidence of accidental awareness during Caesarean section was ~1:670 (1:380-1300). Two-thirds (82, 66%) of cases of accidental awareness experiences arose in the dynamic phases of anaesthesia, namely induction of and emergence from anaesthesia. During induction of anaesthesia, contributory factors included: use of thiopental, rapid sequence induction, obesity, difficult airway management, NMB, and interruptions of anaesthetic delivery during movement from anaesthetic room to theatre. During emergence from anaesthesia, residual paralysis was perceived by patients as accidental awareness, and commonly related to a failure to ensure full return of motor capacity. One-third (43, 33%) of accidental awareness events arose during the maintenance phase of anaesthesia, mostly due to problems at induction or towards the end of anaesthesia. Factors increasing the risk of accidental awareness included: female sex, age (younger adults, but not children), obesity, anaesthetist seniority (junior trainees), previous awareness, out-of-hours operating, emergencies, type of surgery (obstetric, cardiac, thoracic), and use of NMB. The following factors were not risk factors for accidental awareness: ASA physical status, race, and use or omission

  15. Tétano acidental no Estado do Ceará, entre 2002 e 2005 Accidental tetanus in the State of Ceará, between 2002 and 2005

    Directory of Open Access Journals (Sweden)

    Alexsandra Rodrigues Feijão

    2007-08-01

    Full Text Available Descrevem-se as características demográficas e clínicas de indivíduos com tétano acidental no Ceará. Analisou-se, retrospectivamente, 131 casos de tétano acidental notificados em hospital de referência estadual entre 2002 e 2005. Destes, a maioria (84,8% ocorreu entre homens e em moradores da zona urbana (93,2%. A faixa etária com maior incidência foi a de 35 a 49 anos (35,2%. História vacinal completa esteve relatada em quatro (3% casos, sendo ferimento perfurocortante o mais observado, e os membros inferiores os mais acometidos. O trismo esteve relacionado a 86,2% dos casos, seguido por contraturas (54,1%. Entre os notificados houve 95,5% confirmados, cujo óbito incidiu em 33 (26,4% pacientes. Conclui-se que o tétano acidental no Ceará atinge a população de maneira expressiva, apesar de ser uma doença imunoprevinível. Urge autoridades e órgãos gestores da saúde programarem estratégias que visem mudanças de políticas públicas relacionadas à cobertura vacinal dos susceptíveis, principalmente adultos.The demographic and clinical characteristics of individuals with accidental tetanus in Ceará are described. This was retrospective analysis of 131 cases of accidental tetanus notified in a state referral hospital between 2002 and 2005. Most of these cases (84. 8% occurred among men and among people living in the urban zone (93. 2%. The age group with highest incidence was between 35 and 49 years old (35. 2%. A complete vaccination history was reported in four (3% cases. Puncturing/cutting wounds were the cause most commonly observed and the legs were the area most affected. Trismus (lockjaw was reported in 86. 2% of the cases, followed by muscle contractions (54. 1%. Among the notified cases, 95. 5% were confirmed and 33 patients (26. 4% died. We conclude that accidental tetanus in Ceará significantly affects the population, in spite of being a disease that is preventable by immunization. The health authorities and health

  16. Helping Children Exposed to Domestic Violence

    Science.gov (United States)

    ... Families Guide - Search Spanish Facts for Families Guide Domestic Violence and Children No. 109; Updated April 2013 As many as ... get the help they need. When there is domestic violence between partners, there is often child abuse as well. Sometimes children get hurt accidentally. ...

  17. Accidental Hypothermia,

    Science.gov (United States)

    1988-03-03

    the pulmonary , digestive, and endocrine systems.16� Cardiovascular Cardiovascular responses in hypothermia are vell described. Following an early...decline. Included in this group are patients with hypothalamic lesions and agenesis of the corpus callosum, termed the Shapiro Syndrome.46 1�...Hypothermia with agenesis of the corpus callosum has also been associated with hypercalcemia and status epilepticus.230 Since experimental sectioning of the

  18. Accidental goodness?

    DEFF Research Database (Denmark)

    Richter, Anne

    In postmodern capitalist market economies, management of the single organisation is bound to be guided by several rationales, which are in conflict with each other. For some writers this perception leads to the argument, that conceptions of management should strive towards goals beyond the present...

  19. [Accidental falls].

    Science.gov (United States)

    Inokuchi, Koichi

    2013-06-01

    Falls are common cause of injuries among elderly people, and fractures are the most serious consequence of falls. For seniors, hip fractures are the second major cause of bedridden. The feature and acute care of head injury, spinal cord injury, vertebrae fracture, and hip fracture are described. Just had fracture fixation, the patient can not go back to the original ADL. In order not to become bedridden, both medication and physical examination are important based on the new disease concept of locomotive syndrome. To do so, requires hospital and clinic cooperation. Sufficient cooperation is not currently possible, and spread of liaison service is essential.

  20. Improving the knowledge of environment around French nuclear facilities for better dose assessment and post-accidental management

    Energy Technology Data Exchange (ETDEWEB)

    Parache, V.; Renaud, P. [Institut de Radioprotection et de Surete Nucleaire - IRSN (France)

    2014-07-01

    The consequences of an industrial pollution for the population and the environment depend not only on the nature and extent of the pollution, but also of the characteristics of concerned environment: the use that man made of it, and of the man's habits, notably food practices. To improve the consideration of the specificities of territories in its evaluations and its recommendations, in normal operation or in accident and post-accident situations, the Institute for Radioprotection and Nuclear Safety characterizes the environment of the nuclear installations. This standardised measurement of the environmental and population characteristics will be useful in risk assessment and management, and in all the operational stages of a nuclear installation. This characterization concerns the inventory of the main agricultural productions (vegetable and animal), the important agricultural dates (seeding, harvest) and the practices and eating habits of animals, the industry and the local food-processing, as well as on the food practices of the persons which live around the French nuclear power plant. National surveys have identified the major characteristics of French eating habits. Above and beyond the fact that these surveys do not consider local specificities, the use of their results for dosimetric assessments has certain drawbacks: the categories of foodstuffs most vulnerable to contamination in post-accident situations (fresh fruit and vegetables, fresh milk and cheeses) are very rarely described in detail; representation of the eating habits of an 'average' population does not give us as the behaviors of the most sensitive groups. The prime objective of local studies is to describe eating habits (rations and local production rates) of potentially most exposed population around nuclear facilities which may cultivate various foodstuffs. These comparative studies highlighted the important variability of the particular eating habits of the French population

  1. Numerical research of a super-large cooling tower subjected to accidental loads

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yi; Lin, Feng [Department of Building Engineering, Tongji University, Shanghai 200092 (China); Gu, Xianglin, E-mail: gxl@tongji.edu.cn [Department of Building Engineering, Tongji University, Shanghai 200092 (China); Lu, Xiaoqin [Guangdong Electric Power Design Institute, Guangzhou 510660 (China)

    2014-04-01

    With the continued development of nuclear power plants, more and more super-large cooling towers are to be built in China and around the world. For the safe operation of nuclear power plants, research work has been done on the causes of collapse of cooling towers, collapse modes and the secondary disasters caused by the collapse of cooling towers. However, the collapse modes and the ground vibration induced by the collapse of cooling towers subjected to the accidental loads have not been fully understood. This paper has been focused on the modes and mechanisms behavior of the collapse of cooling towers subjected to accidental loads. Meanwhile, prediction of the ground vibration due to the collapse of the cooling towers has also been completed in a parallel project. Using dynamic finite element program LS-DYNA, a 3D finite element model for a super-large cooling tower was developed and the nonlinear material models were incorporated. In this paper, four types of accidental loads were considered to trigger the collapse or local failure of the tower, including vehicle collision, airplane impact, local explosion and missile attack. It was found that vehicle collision, missile attack and small TNT equivalent explosives (2 kg, 20 kg, 200 kg) might result in local failure of the cooling tower, however, the tower can still keep stable. On the other hand, large TNT equivalent explosives (2000 kg, 4500 kg) could cause severe damages in the inclined columns of the cooling tower, and lead to progressive collapse of the entire cooling tower. The two kinds of TNT equivalent explosives caused the same collapse mode while the collapsing duration was different. The airplane impacted at the throat of the cooling tower caused the local failure of shell structure of the tower, and then the progressive collapse of the cooling tower happened due to the gravitational action. The resulting collapse mode was different from that triggered by the local explosion.

  2. Menace of childhood non-accidental traumatic brain injuries: A single unit report

    Directory of Open Access Journals (Sweden)

    Musa Ibrahim

    2015-01-01

    Full Text Available Background: Childhood traumatic brain injury (TBI has high rate of mortality and morbidity worldwide. There are dearths of reports from developing countries with large paediatric population on trauma; neurosurgery trauma of nonaccidental origin is not an exemption. This study analysed menace of non-accidental TBI in the paediatric population from our center. Materials and Methods: This is a single unit, retrospective study of the epidemiology of non-accidental TBI in children starting from September, 2008 to March, 2014. The management outcomes of the epidemiology of the non-accidental TBI were analysed. Results: Total of 109 children age range from 0 (intra-natal to 16 years with a mean of 5.8 ± 4.6 years (median, 5 years were enrolled into the study. 34 (31.2% were domestic violence, 26 (23.9% street assaults, 16 (14.7% were due to animal assaults and mishaps, 17 (15.6% fall from heights. Seven (6.4% cases of collapsed buildings were also seen during the period. Four (3.7% industrial accidents and two (1.8% were self-inflicted injuries. There were also three (2.8% cases of iatrogenic TBI out of which two infants (1.8% sustained TBI from cesarean section procedure while one patient (0.9% under general anaesthesia felt from the operation bed resulting to severe TBI. Conclusion: Child abuse, unprotected child labour, parental/care-givers negligence are the main cause of nonaccidental TBI. Human right activists and government agents should be incorporated in curtailing the menace.

  3. Accidentes percutáneos con riesgo biológico, producidos por dispositivos de seguridad en la Comunidad de Madrid Percutaneous injuries with biological risk caused by security devices in Madrid Community

    Directory of Open Access Journals (Sweden)

    María Clemente Yélamos

    2012-06-01

    Full Text Available Desde la implantación en 2006, de procedimientos seguros y un Sistema de Vigilancia de Accidentes Biológicos en el ámbito sanitario de la Comunidad de Madrid, se viene observando un aumento de los accidentes percutáneos relacionados con la utilización de Dispositivos de Seguridad. Con la finalidad de estudiar los factores contribuyentes a la producción de accidentes con estos nuevos dispositivos, se realiza un estudio descriptivo longitudinal prospectivo de los accidentes notificados a lo largo de 6 meses (2010-2011. Se incluyen 378 accidentes, el 86% afectó a mujeres, siendo la tasa de incidencia en enfermería de 14,3 y entre facultativos de 3,1 (accidentes por mil. Las agujas subcutáneas fueron las más implicadas (25,7%. En el 6,6% de los accidentes se había inactivado intencionadamente su mecanismo de seguridad y solo un 2,6% podría imputarse a un fallo del dispositivo. Entre los factores externos que han podido contribuir destacan "apremio de tiempo/ritmo de trabajo elevado" (46,5% y "realizar la maniobra con posturas incómodas" (31,5%. Las intervenciones para prevenir Accidentes Biológicos deben ser específicas para cada categoría profesional y área de trabajo. Se debe seguir apostando por la introducción de Dispositivos de Seguridad, identificar los factores contribuyentes e implementar acciones individualizadas que minimicen los riesgos.Since the implementation in 2006 of security procedures and a surveillance system of biological accidents in Madrid public health services, an increase of percutaneus accidents related to the use of safety devices has been observed. With the purpose of studying the external factors to the production of accidents with these new devices, there is realized a prospective, longitudinal and descriptive study of the accidents happened throughout six months (2010-2011. 378 accidents are included, 86% happened in women, the incidence rate being 14.3 accidents per thousand in nurses, and 3.1 in

  4. Salade malade: malignant ventricular arrhythmias due to an accidental intoxication with Aconitum napellus.

    Science.gov (United States)

    Weijters, B J; Verbunt, R J A M; Hoogsteen, J; Visser, R F

    2008-01-01

    Intoxication with Aconitum napellus is rare in our regions. Aconite alkaloids can cause ventricular arrhythmia by a prolonged activation of sodium channels. Because the margin of safety is low between the analgesic and toxic dose, intoxication is not rare when Aconite is used in herbal medicine. We present a case in which a 39-year-old male was accidentally intoxicated with Aconite. Even though no antidote or adequate therapy is available he was successfully resuscitated. (Neth Heart J 2008;16:96-9.).

  5. Terapéuticas intervencionistas para el accidente cerebrovascular isquémico

    OpenAIRE

    Rabadán, Alejandra T.; Luciano Sposato; Claudio Mazia

    2010-01-01

    En los últimos 20 años se han desarrollado nuevas opciones para el tratamiento y para la prevención del accidente cerebrovascular (ACV) isquémico, muchas de ellas de carácter intervencionista, tales como la endarterectomía carotídea y la trombolisis intravenosa con activador tisular del plasminógeno. La evidencia científica ha llevado a su difusión y utilización en países desarrollados mientras que en naciones emergentes se observa un retraso en su adopción. Otras modalidades terapéuticas que...

  6. Accidentes de tránsito fatales en Costa Rica en el 2007

    Directory of Open Access Journals (Sweden)

    Maikel Vargas Sanabria

    2008-09-01

    Full Text Available Los accidentes de tránsito en Costa Rica contribuyen significativamente con la tercera causa de muerte en el país en los últimos años: las causas externas, por ello resulta importante conocer el panorama más reciente de las fatalidades causadas por estos eventos. En el presente trabajo se analizarán desde el punto de vista médico legal los accidentes de tránsito fatales, cuyas víctimas fallecieron en el año 2007. Para ello se revisaron todas las autopsias efectuadas (un total de 3003 en el Departamento de Medicina Legal de Costa Rica para ese año. Se obtuvo que una cuarta parte de las mismas se originaron en accidentes de tránsito, lo cual generó una tasa de mortalidad de 16,58 por 100000 habitantes, considerada alta a nivel mundial. El perfil predominante de las víctimas fue: ser de género masculino, en edad económicamente productiva, con accidentes fatales de predominio en la noche, los fines de semana, en las provincias costeras, con fallecimiento en el sitio del hecho por trauma cráneo cervical en ocupantes de automotores o peatones, de los cuales un porcentaje significativo estaba bajo los efectos del alcohol y muy pocos bajo los efectos de otras drogas de abuso. Se insiste en la prevención como la herramienta fundamental para evitarlos.Traffic accidents in Costa Rica have been a contributing cause of death (the third cause of death over the last years; that ’s why its is a mayor issue to know the panorama of the latest fatalities caused by this events. In this article, it will be analyzed from the legal medicine point of view, the fatal transit accidents during the year 2007. For these reason all autopsies (a total of 3003 occurred during that year which were made by the Departamento de Medicina Legal de Costa Rica were reviewed. From these revision, it was obtained that one forth of these autopsies were transit accidents, which means that the mortality rate was 16,58 per 100000 habitants, that is consider high over the

  7. Acute ischaemia of the leg following accidental intra-arterial injection of dissolved flunitrazepam tablets.

    Science.gov (United States)

    Leifert, J A; Bossaller, L; Uhl, M

    2008-11-01

    Accidental intra-arterial injection of drugs is a sporadic complication in i.v. drug addicts. A 22-year-old drug-abuser injected flunitrazepam tablets dissolved in tap water into her left femoral artery and presented with clinical signs of acute ischaemia of the left leg. Severe rhabdomyolysis developed within 5 hours after the injection. Selective arterial catheter angiography showed an acute occlusion of the posterior tibial artery. Combination therapy with i.a. urokinase, i.a. prostaglandines and i.v. anticoagulation resulted in re-opening of the obstructed distal artery and complete cessation of symptoms.

  8. Problems in experimental and mathematical investigations of the accidental thermalhydraulic processes in RBMK nuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Nigmatulin, B.I.; Tikhonenko, L.K. [Engineering Centre (EREC) for Nuclear Plants Safety, Electrogorsk (Russian Federation); Blinkov, V.N. [Aviation Institute, Kharkov (Ukraine)] [and others

    1995-09-01

    In this paper the thermalhydraulic scheme and peculiarities of the boiling water graphite-moderated channel-type reactor RBMK are presented and discussed shortly. The essential for RBMK transient regimes, accidental situations and accompanying thermalhydraulic phenomena and processes are formulated. These data are presented in the form of cross reference matrix (version 1) for system computer codes verification. The paper includes qualitative analysis of the computer codes and integral facilities which have been used or can be used for RBMK transients and accidents investigations. The stability margins for RBMK-1000 and RBMK-1500 are shown.

  9. The present status and recent applications of the accidental tritium assessment code UFOTRI

    Energy Technology Data Exchange (ETDEWEB)

    Raskob, W. [Forschungszentrum Karlsruhe GmbH, Institut fuer Neutronenphysik und Reaktortechnik, Karlsruhe (Germany)

    1999-03-01

    The computer program UFOTRI can be used for assessing the impact of accidental released tritium in the two chemical forms tritiated water vapour and tritium gas. By applying UFOTRI to potential European sites for ITER, it could be demonstrated that the main goal, the nonevacuation criteria, is fulfilled for the present release limits. Contributions in international studies together with the re-evaluation of experimental data showed that the plant sub-model as well as the soil sub-model are areas for further improvement. (author)

  10. Accidental ingestion of a barbed wire broach and its endoscopic retrieval: Prevention better than cure

    Directory of Open Access Journals (Sweden)

    Rajashekar Mohan

    2011-01-01

    Full Text Available Ingestion of instruments is a potential complication that can occur during dental procedures. We report a case of accidental ingestion of an endodontic barbed wire broach during root canal treatment and its subsequent retrieval by endoscopic methods. Although prevention is the best approach, proper management of such an event is also crucial. The objective of this report is to draw attention to the potentially serious complications that can occur if preventive techniques are not practised, and to discuss the accepted guidelines for management of such an event.

  11. Forecasting consequences of accidental release: how reliable are current assessment models

    Energy Technology Data Exchange (ETDEWEB)

    Rohwer, P.S.; Hoffman, F.O.; Miller, C.W.

    1983-01-01

    This paper focuses on uncertainties in model output used to assess accidents. We begin by reviewing the historical development of assessment models and the associated interest in uncertainties as these evolutionary processes occurred in the United States. This is followed by a description of the sources of uncertainties in assessment calculations. Types of models appropriate for assessment of accidents are identified. A summary of results from our analysis of uncertainty is provided in results obtained with current methodology for assessing routine and accidental radionuclide releases to the environment. We conclude with discussion of preferred procedures and suggested future directions to improve the state-of-the-art of radiological assessments.

  12. Is Project Management Still an Accidental Profession? A Qualitative Study of Career Trajectory

    Directory of Open Access Journals (Sweden)

    Tracey M. Richardson

    2015-02-01

    Full Text Available In this study, the authors used qualitative techniques to look for reoccurring themes related to 87 project managers’ responses to interview questions associated with entry into the field of project management and career progression. The study found that despite the efforts of higher education, professional associations, and their professional development and certifications, the project management remains a destination by accident. Professional project managers do not intend to be project managers but “fall into” the profession. This study provides a conceptual framework for project manager career trajectory that has implications for project management training and mentoring and contributes to the growing literature on the accidental profession.

  13. Measurement of accidental coincidences in beta-gamma coincidence counting using non-equal dead times

    CERN Document Server

    Hwang, H Y; Cho, Y H; Byun, J I; Kim, T S; Park, T S; Lee, J M

    2002-01-01

    It is shown that the multi-channel time-scaling (MCTS) method is particularly suitable for the direct measurement of accidental coincidences even if the dead times of the two counting channels are of different length. We prepared five samples, with activities from 900 to 2100 s sup - sup 1. The dead time of the gamma channel was 12 mu s for all measurements, but for the beta channel it varied from 12 to 20 mu s. The true coincidence rates determined by the MCTS method are compared with those obtained by using conventional technique.

  14. Transferencia del aprendizaje motor en pacientes con antecedentes de accidente cerebrovascular: serie de casos

    OpenAIRE

    Karen Castro-Medina; Mayra Pérez-Páez; Fabiola Moscoso-Alvarado; Clarice Tanaka

    2015-01-01

    Antecedentes. La rehabilitación es un proceso de reaprendizaje motor, que mejora el desempeño en términos de adquisición de nuevas habilidades y adaptación o refinamiento de habilidades aprendidas previamente. A pesar de este conocimiento, existen, considerablemente, pocos estudios que describan el aprendizaje motor después de un accidente cerebrovascular (ACV) y la relevancia del mismo en los procesos de rehabilitación y recuperación. Objetivo. Describir la transferencia del aprendizaje moto...

  15. Accidental swallowing of a gold cast crown during orthodontic tooth separation.

    Science.gov (United States)

    Kharbanda, O P; Varshney, P; Dutta, U

    1995-01-01

    Accidental swallowing of a gold cast crown that became loose after separation with brass wire for orthodontic band placement, is reported. The intervention to remove the ingested crown subsequent to its location in the GI tract on immediate radiographic examination of chest and abdomen included endoscopic examination. Since the crown had past distal to the duodenum it was decided to keep a watch on its movement by daily radiographic examination. The crown passed with excreta on the 5th day uneventfully. Literature on ingestion of foreign bodies of dental origin is reviewed. Possible emergencies and their management is discussed.

  16. Muertes por enfermedades cardiacas y accidentes cerebrovasculares prevenibles - (Preventable Deaths from Heart Disease and Stroke)

    Centers for Disease Control (CDC) Podcasts

    2013-09-03

    Este podcast se basa en la edición de septiembre del 2013 del informe Signos Vitales de los CDC. Más de 800,000 personas en los Estados Unidos mueren cada año a causa de enfermedades cardiacas y accidentes cerebrovasculares. Aprenda cómo controlar todos los principales factores de riesgo.  Created: 9/3/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 9/3/2013.

  17. A model of neutrino mass and dark matter with an accidental symmetry

    Directory of Open Access Journals (Sweden)

    Amine Ahriche

    2015-06-01

    Full Text Available We present a model of radiative neutrino mass that automatically contains an accidental Z2 symmetry and thus provides a stable dark matter candidate. This allows a common framework for the origin of neutrino mass and dark matter without invoking any symmetries beyond those of the Standard Model. The model can be probed by direct-detection experiments and μ→e+γ searches, and predicts a charged scalar that can appear at the TeV scale, within reach of collider experiments.

  18. Comportamiento general de los accidentes provocados por animales venenosos en colombia, 2006-2010

    OpenAIRE

    Rodríguez Vargas, Ariadna Lorena; Rodríguez Buitrago, Javier Roberto; Díaz González, Gonzalo Jair

    2013-01-01

    Objetivo El conocimiento parcial de estadísticas nacionales acerca de accidentalidad por animales venenosos, con distribución geográfica en Colombia, motiva el estudio de dichas circunstancias. El objetivo fue realizar una línea base de los accidentes por animales venenosos reportados de forma telefónica al Centro de Investigación, Gestión e Información Toxicológica de la Universidad Nacional de Colombia (CIGITOX), provenientes de todo el país, y cuyo registro se encontraba en bases de datos ...

  19. The accidental potential of diffractive thinking technologies. Mapping and colouring social differentiation in/of school

    DEFF Research Database (Denmark)

    Staunæs, Dorthe; Brown, Rikke; Bjerg, Helle

    This paper presents our joint work with using and developing Donna Haraways concept of thinking technologies for putting research into play in cooperation with practitioners within the field of education. First we shortly present the conceptualization of thinking technologies and why we have found...... this conceptualization useful in our work and cooperation with practitioners. Secondly we present the development of the ‘colour map’ as a specific example of a thinking technology and introduce what we shall coin as the accidental potential of working with research informed thinking technologies on the particular...

  20. The long-term prediction of return to work following serious accidental injuries: A follow up study

    Directory of Open Access Journals (Sweden)

    Sensky Tom

    2011-04-01

    Full Text Available Abstract Background Considerable indirect costs are incurred by time taken off work following accidental injuries. The aim of this study was to predict return to work following serious accidental injuries. Method 121 severely injured patients were included in the study. Complete follow-up data were available for 85 patients. Two weeks post trauma (T1, patients rated their appraisal of the injury severity and their ability to cope with the injury and its job-related consequences. Time off work was assessed at one (T2 and three years (T3 post accident. The main outcome was the number of days of sick leave taken due to the accidental injury. Results The patients' appraisals a of the injury severity and b of their coping abilities regarding the accidental injury and its job-related consequences were significant predictors of the number of sick-leave days taken. Injury severity (ISS, type of accident, age and gender did not contribute significantly to the prediction. Conclusions Return to work in the long term is best predicted by the patients' own appraisal of both their injury severity and the ability to cope with the accidental injury.

  1. Fallout: The experiences of a medical team in the care of a Marshallese population accidently exposed to fallout radiation

    Energy Technology Data Exchange (ETDEWEB)

    Conard, R.A.

    1992-09-01

    This report presents an historical account of the experiences of the Brookhaven Medical Team in the examination and treatment of the Marshallese people following their accidental exposure to radioactive fallout in 1954. This is the first time that a population has been heavily exposed to radioactive fallout, and even though this was a tragic mishap, the medical findings have provided valuable information for other accidents involving fallout such as the recent reactor accident at Chernobyl. Noteworthy has been the unexpected importance of radioactive iodine in the fallout in producing thyroid abnormalities.

  2. Symmetry-Guaranteed and Accidental Nodal-Line Semimetals in FCC Lattice

    CERN Document Server

    Kawakami, Takuto

    2016-01-01

    We demonstrate theoretically that nodal-line semimetal (NLS) states can be realized in face-center-cubic (fcc) lattice with orbits belonging to one irreducible representation, such as [$p_x$, $p_y$, $p_z$] and/or [$d_{xy}$, $d_{xz}$, $d_{yz}$]. It is shown that the three orbits are subdivided with respect to the odd- and even-parity upon mirror reflection on high symmetry planes, which yields an analytic expression for the trajectory of NL in momentum space when a tight-binding (TB) model is adopted. It becomes clear that there are two kinds of NLs, a symmetry-guaranteed one around the surface of the first Brillouin zone (BZ), and an accidental one around the BZ center governed by the hopping integrals. As a realization of the idea, we analyze the fcc photonic crystal composed of dielectric spheres by solving the Maxwell's equations. Two symmetry-guaranteed and one accidental NLS photonic states are observed. This provides a good platform to confirm experimentally the existence of topological NLS state, and o...

  3. Cuidados de Enfermería en el Accidente Ofídico

    Directory of Open Access Journals (Sweden)

    Lorenzo Hernández, María Piedad

    2013-04-01

    Full Text Available El accidente ofídico supone una emergencia médica que requiere atención médica inmediata, pudiendo provocar la muerte de no realizarse una actuación adecuada precoz. El tratamiento varía según la geografía y características de las serpientes autóctonas, existiendo múltiples protocolos, que en ocasiones resultan contradictorios. El objetivo de este trabajo es realizar el proceso de atención de enfermería en el accidente ofídico, siendo imprescindible poseer un conocimiento integral de las especies peligrosas en España, consecuencias de la mordedura y tratamiento específico. Para la elaboración de este artículo se revisó la bibliografía para poner de manifiesto el plan de actuación y cuidados enfermeros. Con la elaboración de un plan de atención de enfermería individualizado se disminuye el riesgo de secuelas y se proporciona un cuidado y una atención sanitaria de calidad.

  4. Plutino 15810 (1994 JR1), an accidental quasi-satellite of Pluto

    CERN Document Server

    Marcos, C de la Fuente

    2012-01-01

    In the solar system, quasi-satellites move in a 1:1 mean motion resonance going around their host body like a retrograde satellite but their mutual separation is well beyond the Hill radius and the trajectory is not closed as they orbit the Sun not the host body. So far, minor bodies temporarily trapped in the quasi-satellite dynamical state have been identified around Venus, Earth, the dwarf planet (1) Ceres, the large asteroid (4) Vesta, Jupiter, Saturn and Neptune. Using computer simulations, Tiscareno and Malhotra have predicted the existence of a small but significant population of minor bodies moving in a 1:1 mean motion resonance with Pluto. Here we show using N-body calculations that the Plutino 15810 (1994 JR1) is currently an accidental quasi-satellite of Pluto and it will remain as such for nearly 350,000 yr. By accidental we mean that the quasi-satellite phase is triggered (or terminated) not by a direct gravitational influence in the form of a discrete close encounter but as a result of a resonan...

  5. Implications for platform re-assessment based on in-service damage resulting from accidental loadings

    Energy Technology Data Exchange (ETDEWEB)

    Sharp, J.V.; Stacey, A. [Health and Safety Executive, London (United Kingdom); Frieze, P.A.; Nichols, N.W.

    1996-12-01

    Current offshore design codes enable the capacity of structural components to be determined, but the equations apply only to the undamaged state. The ability to assess the performance of such components containing damage has only recently been developed and is important in the re-assessment of structures. In particular knowledge of the performance of members which are dented or bowed as a result of accidental damage is important in establishing the capacity of structures in-service, when for example using pushover analyses. Much research has been taken on the capacity of dented and bowed members. This paper reviews this data and establishes a database using screening criteria. This data is then compared with theoretical predictions from recently developed draft ISO equations. These show that dents and bows can significantly reduce the performance of members. A survey of offshore damage resulting in repairs has shown that 30% of this damage is the result of accidental events such as ship impact and dropped objects. Most damage found to members was in the form of dents, bows and cracks, with member severance in a few cases. The implications of this information for reassessment and offshore inspections are considered.

  6. Evaluation of patients who admitted to hospital due to accidentally falling objects on them

    Directory of Open Access Journals (Sweden)

    Yahya Turan

    2015-03-01

    Full Text Available Objective: Accidents at home, office, or outdoor environment are one of the leading cause of injury and death, especially in children. The aim of this study is the evaluation of patients admitted to our hospital due to the falling on an object accidentally. Methods: This study retrospectively assessed the medical records of 135 patients who were accidentally injured by a heavy object that fell on them between 2012 and 2014. Age, sex, object type as the cause of incident, site and time of the incident, and the death cause were analyzed. Results: Eighty-two (60.7% patients were male and 53 (39.3% were female and the mean age of the study population was 18.8 (0-79 years. The patients were most commonly from the pediatric age group (0-18 years old (n=78, 57.8%. When falling objects types are evaluated respectively dropping on a television with 18.5% (25 patients, stone(s with 15.6% (21 patients and objects made of iron with 11.1% (15 patients shares first three places. The most common sites of the incident were home (n=85, 62.9%. The incidents most commonly occurred in summer months (n=93, 68.9%. Conclusion: In this study obtained data should be contributed to accident prevention programs especially for children.

  7. Accidental phosgene gas exposure: A review with background study of 10 cases

    Directory of Open Access Journals (Sweden)

    Arvind Kumar Vaish

    2013-01-01

    Full Text Available Here, authors present a review on clinical presentation and management of exposure of phosgene gas after reviewing the literature by searching with keywords phosgene exposure on Google, Cochrane, Embase and PubMed with a background of experience gained from 10 patients who were admitted to our institute after an accidental phosgene exposure in February 2011 nearby a city in India. Phosgene is a highly toxic gas, occupational workers may have accidental exposure. The gas can also be generated inadvertently during fire involving plastics and other chemicals and solvents containing chlorine, which is of concern to emergency responders. Phosgene inhalation may cause initially symptoms of respiratory tract irritation, patients feel fine thereafter, and then die of choking a day later because of build up of fluid in the lungs (delayed onset non-cardiogenic pulmonary edema. Phosgene exposure is associated with significant morbidity and mortality. Patients with a history of exposure should be admitted to the hospital for a minimum of 24 h for observation because of the potential for delayed onset respiratory failure and acute respiratory distress syndrome.

  8. Accidental contamination of a German town's drinking water with sodium hydroxide.

    Science.gov (United States)

    Lendowski, Luba; Färber, Harald; Holy, Andreas; Darius, Anke; Ehrich, Bernd; Wippermann, Christine; Küfner, Bernd; Exner, Martin

    2015-05-01

    Case report of a very serious drinking water incident putting up to 50,000 inhabitants of a town near Bonn in North Rhine-Westphalia, Germany at risk. A concentrated solution of highly alkaline water by sodium hydroxide was accidentally washed into the town's drinking water at a pumping station and increased the pH-value of the water to 12. Residents who came into contact with the contaminated water immediately had a toxic reaction. The incident was detected by complaints from customers and after that was stopped within several hours. The pipes were flushed and the customers were warned not to use the water till the all clear. After this immediate management there was an investigation and the cause of the incident was detected as an accidental release of accumulated sodium hydroxide (NaOH) solution. The lack of a network alarm system and the automatic cut-off mechanisms as deficiencies in the design of the station were rectified by the water company immediately after the incident.

  9. Accidental fatal poisoning of a dog by Dieffenbachia picta (dumb cane).

    Science.gov (United States)

    Loretti, Alexandre Paulino; da Silva Ilha, Marcia Regina; Ribeiro, Rita Elaine Streda

    2003-10-01

    A single case of accidental fatal poisoning by Dieffenbachia picta, (dumb cane) (Araceae) in a 9-y-old female Poodle is described. Clinical signs included severe, locally extensive erosive/ulcerative glossitis accompanied by marked dyspnea of acute onset. The animal did not respond to emergency procedures to relieve severe respiratory distress; fatal asphyxiation ensued from edema of the glottis a few hours after the first clinical signs were observed. According to the owner, the dog had access to a tall, potted dumb cane plant and chewed the thick stem of the plant intensely. The owner did not authorize a necropsy of the animal. The diagnosis of Dieffenbachia picta poisoning was based on the history of accidental consumption of dumb cane and clinical signs. A comparison of this single case with other reports of dumb cane poisoning suggests that dogs poisoned by Dieffenbachia species usually recover uneventfully with conservative management and that death from asphyxiation is a rare but possible consequence of this intoxication. Severe edematous swelling of the glottis with occlusion of the larynx airway passage can occur in those cases in which large amounts of sap are quickly squeezed from the plant during intense chewing. Death would occur if owners do not seek veterinary care immediately and if emergency procedures are not instituted on time.

  10. Caregivers' voices: The experiences of caregivers of children who sustained serious accidental and non-accidental head injury in early childhood.

    Science.gov (United States)

    Wharewera-Mika, Julie; Cooper, Erana; Kool, Bridget; Pereira, Susana; Kelly, Patrick

    2016-04-01

    Head injury is a leading cause of mortality and acquired neurological impairment in children. Head-injured children may have neurobehavioural deficits that persist for years following injury. Head injury can result in significant and persistent caregiver burden, including mental health issues, family stress and disorganisation, and unmet social and healthcare service needs. Few studies have examined the healthcare and social service needs of children and their families following head injury sustained at an early age. This qualitative study aims to describe the experiences of caregivers of children who sustained a serious head injury (particularly non-accidental head injury) before the age of 2 years. Caregivers were interviewed up to 15 years following the initial injury. Semi-structured interviews with 21 caregivers of 15 children (aged 3-15 years at the time of interview) were completed. Thematic analysis of interview data generated three key themes: impact, support and information. The study's findings reveal the broad impact of serious childhood head injury on caregivers, specifically the significant distress and burden brought about through lack of information, challenges in accessing support and inconsistent care. Recommendations for developing a quality 'model of care' and improving ease of access to supports for caregivers are provided.

  11. Long-term follow-up after accidental gamma irradiation from a {sup 192}Ir source in Bangladesh

    Energy Technology Data Exchange (ETDEWEB)

    Mollah, A.S.; Begum, A.; Begum, R. [Bangladesh Atomic Energy Commission, Dhaka (Bangladesh)

    2006-07-01

    A industrial radiographer was accidentally over -exposed to high dose of ionizing radiation from an {sup 192}Ir source pellet during radiograph y of weld-joints in gas pipe-lines on June 10, 1985 in Bangladesh. The source, housed in a portable exposure assembly, had an activity of about 1850 GBq. A guide -tube was used to control the transfer of the source from safe storage position to the exposure position and vice versa. For radiography, the ti p of the guide tube was to be fixed to the weld -joint while the source was cranked to the exposure position. Following the elapse of the preset exposure time the source had to be cranked back to the safe stor age position. This procedure was to be repeated for each radiographic exposure. Symptoms of high radiation exposure occurred immediately after the accident and skin erythema developed leading to progressive tissue deteriorations. Biological effects such as mild vomiting, malaise, nausea and diarrhea occurred within a short period after the accident. Skin erythema, swelling and tenderness of the palmar surfaces and the tips of the thumbs, index fingers and middle fingers of the both hands accompanied by severe pain and inflammation developed within 7 days of the mishap. The inflammatory changes characterized by redness and bullae spread over the affected fingers with severe pain and agony within a few days. The finger -tips developed abscesses with enormous pus formation and the affected finger nails fell off. He also developed toothache. At this stage a medical practitioner made some surgical dressings and prescribed antibiotics. During the first six months the most serious health disorder was local necroses of the skin and the deep layers of the palmar side of the affected fingers with sharply delineated injuries. The clinical findings were consistent with those reported elsewhere under similar accident conditions. The consequences of this over-exposure are being followed up to assess the long-term effects of

  12. 49. Biological dose assessment by the analyses of chromosomal aberrations and CB micronuclei in two victims accidentally exposed to 60Co gamma-rays

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@Biological doses were estimated by using the yields of dicentrics plus rings(dic+r) and cytokinesis-block micronuclei (CBMN) for two victims of the 60Co radiation source accident occurred on Mar 6,2001 in the City of Xuchang(victim A), and Jun 26,2001 in the City of Kaifeng(victim B), Henan Province, respectively. The whole blood of the victim A (male, 37 years old) and the victim B (female, 27 years old)

  13. Prescripción facilitada de drogas antihipertensivas y disminución de la muerte prematura por accidente cerebrovascular

    OpenAIRE

    Javier Mariani; Marina Ridao; Gabriel González; Mauricio Monsalvo; Alejandro Macchia

    2016-01-01

    Introducción: Desde 2003, el programa Remediar (+Redes) distribuye gratuitamente medicación antihipertensiva. Durante este período, la mortalidad por accidente cerebrovascular disminuyó, aunque con inequidades entre grupos socioeconómicos. Objetivos: Evaluar la asociación entre la mortalidad por accidente cerebrovascular y la provisión de fármacos antihipertensivos. Estudiar la posible interacción entre los efectos de los antihipertensivos sobre la mortalidad y el nivel socioeconómico. ...

  14. Los accidentes coronarios de la terapéutica electro-convulsivante. su patogenia y su prevención

    OpenAIRE

    Jiménez Arango, Alejandro; Hakim Dow, Salomón

    2011-01-01

    a) Se plantea el problema de la aparición de accidentes coronarios en las aplicaciones de electro-choque y se hace un recuento de los casos referidos en la literatura.b) Se presentan las historias de dos casos clínicos: unos de insuficiencia coronaria aguda transitoria y otro de infarto del miocardio, consecutivos a aplicaciones de electro-choque.c) Se propone una explicación fisio-patológica de tales accidentes considerando: 1° La influencia de las lesiones coronarias antiguas. 2° La variabi...

  15. Muerte prematura por accidente cerebrovascular y condición socioeconómica en la Argentina

    OpenAIRE

    Mauricio Monsalvo; Anabel Fernández Prieto; Alejandro Macchia

    2016-01-01

    Introducción: La asociación entre mortalidad por accidente cerebrovascular y el nivel socioeconómico está escasamente descripta en Argentina. Objetivos: Describir la evolución temporal de la mortalidad por accidente cerebrovascular y su asociación con el nivel socioeconómico en Argentina entre 2000 y 2011. Material y métodos: Se realizó un estudio ecológico longitudinal. La mortalidad se cuantificó mediante tasas estandarizadas por edad y sexo, y el nivel socioeconómico mediante quint...

  16. Cancer occurrence among workers exposed to acrylonitrile.

    Science.gov (United States)

    Rothman, K J

    1994-10-01

    A MEDLINE search identified 12 published epidemiologic studies that have reported incidence or mortality experience among workers exposed to acrylonitrile. Many of the studies contain scanty descriptions of subject ascertainment, and most do not have good information on exposure assessment. Many also may have suffered from incomplete follow-up, as evinced by an overall deficit in the number of deaths observed, compared with the number expected from general population mortality rates. Such problems are not unique to studies on acrylonitrile, and to some extent they reflect the difficulties of conducting retrospective cohort studies. Despite these drawbacks, a simplified meta-analysis of the mortality experience reported for these cohorts revealed little evidence for carcinogenicity. Approximately the same number of cancer deaths was observed as was expected according to general population mortality rates (standardized mortality ratio 1.03, 90% confidence interval 0.92-1.15). The combined information from these studies is insufficient to support confidence about a lack of carcinogenicity at all sites. Nevertheless, despite the flaws in some of the individual studies, the summarized findings offer reassurance that workers exposed to acrylonitrile face no striking increases in mortality for all cancers or for respiratory cancer.

  17. Accidental Thawing of Embryos, Cryopreserved for Transfer. Two Italian cases, Milan and Rome.

    Science.gov (United States)

    Busardò, Francesco P; Vergallo, Gianluca Montanari; Turillazzi, Emanuela; Bolino, Giorgio; Vullo, Annamaria; Frati, Paola

    2016-01-01

    The bioethical and juridical debate on the status of frozen embryos sometimes adds new issues arising from new scientific evidence or by accidental occurrences that bring to the attention of the scientific community the need for new practical solutions. Within this scenario, there have been, in recent years, episodes concerning the accidental thawing of embryos, which have been cryopreserved for transfer. Two Italian cases (the Milan and the Rome cases) are here reported: the Milan case involves a couple undergoing artificial insemination. Three eggs were collected for insemination and two of them had been fertilized. During the night of 8/9 May 2007 a short circuit occurred, resulting in an electricity blackout, which caused the loss of the embryos in culture, which should have been transferred to the woman's uterus on 9 May. The couple applied for damage compensation from the hospital following the loss of the embryos. The case went to Court and the result was a judgment issued by the Milan civil court, which recognized that the centre was to blame for irreparable damage to the embryos. The Rome case, involves two couples (A and B) affected by sterility who applied to an authorized public centre to undergo an ART program. Following the medical procedures, two of the embryos produced were transferred to the woman in couple A and five were frozen, whereas three embryos produced by couple B were transferred to the uterus of the woman and six eggs were cryopreserved in the centre. Two years after the procedure there was an electricity blackout, and the backup electricity generator failed to function, causing the loss of the gametes and the embryos cryopreserved in the centre. Legal proceedings begun by the couples to obtain compensation for damages are still underway. The above reported cases have significantly intensified the bioethical debate on the lawfulness of such practices and on the fate of the cryopreserved embryos, at the same time opening new frontiers in

  18. ACUTE ACCIDENTAL POISONING IN CHILDREN: A HOSPITAL-BASED RETROSPECTIVE STUDY

    Directory of Open Access Journals (Sweden)

    Kameshore

    2014-10-01

    Full Text Available INTRODUCTION: Acute accidental poisoning in children is a big problem anywhere in the world. Studies done elsewhere in India showed a wide range of incidence of the problem. Hence, it was felt important to study its magnitude and associated characteristics as of now. OBJECTIVE: The current study was taken up to know the magnitude among children admitted in JNIMS, Imphal which is a newly established medical institute and also to study the characteristics like age, gender, type of poison, duration of hospital-stay and outcome of the cases. MATERIALS & METHODS: Retrospective data of all acute accidental poisoning cases among children admitted in the Pediatrics Ward, JNIMS, Imphal during the period July 2008 - December 2013 were analyzed by using descriptive statistics. RESULT: Of all the 13,663 children admitted, 148 cases were because of acute accidental poisoning giving an incidence rate of 1.08%. The male is to female ratio was 1.31:1. The last three years of the study period showed a slightly increasing trend in the incidence. Children aged 1-4 years were the most commonly affected (65.54%. Kerosene oil was by far the commonest (42% of all the poisonous substances consumed. Food poisoning, poisoning with organic compounds, poisoning with medicinal drugs and poisoning with corrosives comprised 21%, 12%, 9% and 8% respectively of all the cases. There was no mortality. DISCUSSION: The incidence rate of 1.08% as found out from the current study was on the lower side as compared to reports of previous studies done in other parts of the country. Yet, it was two-fold of the incidence reported from RIMS which is situated in the same State. Parental negligence in storing poisonous substances in the household was implicated. They need to be made aware for keeping harmful poisonous substances in safe places out of the reach of children. CONCLUSION: Community-based studies are recommended for estimating more accurately the magnitude of the problem in the

  19. Effect of wet-cold weather transportation conditions on thermoregulation and the development of accidental hypothermia in pullets under tropical conditions.

    Science.gov (United States)

    Minka, Ndazo S; Ayo, Joseph O

    2016-03-01

    The present study examines onboard thermal microclimatic conditions and thermoregulation of pullets exposed to accidental hypothermia during wet-cold weather transportation conditions, and the effect of rewarming on colonic temperature (CT) of the birds immediately after transportation. A total of 2200 pullets were transportation for 5 h in two separate vehicles during the nighttime. The last 3 h of the transportation period was characterized by heavy rainfall. During the precipitation period, each vehicle was covered one fourth way from the top-roof with a tarpaulin. The onboard thermal conditions inside the vehicles during transportation, which comprised ambient temperature and relative humidity were recorded, while humidity ratio and specific enthalpy were calculated. The CT of the birds was recorded before and after transportation. During transportation, onboard thermal heterogeneity was observed inside the vehicles with higher (p transported pullets under tropical conditions and a successful rewarming outcome. In conclusion, transportation of pullets during wet weather at onboard temperature of 18-20 °C induced hypothermia on birds located at the air inlets, which recovered fully after several hours of gradual rewarming.

  20. Walking through Apertures in Individuals with Stroke

    Science.gov (United States)

    Higuchi, Takahiro

    2017-01-01

    Objective Walking through a narrow aperture requires unique postural configurations, i.e., body rotation in the yaw dimension. Stroke individuals may have difficulty performing the body rotations due to motor paralysis on one side of their body. The present study was therefore designed to investigate how successfully such individuals walk through apertures and how they perform body rotation behavior. Method Stroke fallers (n = 10), stroke non-fallers (n = 13), and healthy controls (n = 23) participated. In the main task, participants walked for 4 m and passed through apertures of various widths (0.9–1.3 times the participant’s shoulder width). Accidental contact with the frame of an aperture and kinematic characteristics at the moment of aperture crossing were measured. Participants also performed a perceptual judgment task to measure the accuracy of their perceived aperture passability. Results and Discussion Stroke fallers made frequent contacts on their paretic side; however, the contacts were not frequent when they penetrated apertures from their paretic side. Stroke fallers and non-fallers rotated their body with multiple steps, rather than a single step, to deal with their motor paralysis. Although the minimum passable width was greater for stroke fallers, the body rotation angle was comparable among groups. This suggests that frequent contact in stroke fallers was due to insufficient body rotation. The fact that there was no significant group difference in the perceived aperture passability suggested that contact occurred mainly due to locomotor factors rather than perceptual factors. Two possible explanations (availability of vision and/or attention) were provided as to why accidental contact on the paretic side did not occur frequently when stroke fallers penetrated the apertures from their paretic side. PMID:28103299

  1. Comparative Toxicological Study between Exposed and Non-Exposed Farmers to Organophosphorus Pesticides

    Directory of Open Access Journals (Sweden)

    Fariba Taghavian

    2016-04-01

    Full Text Available Objective: The purpose of this work was to compare DNA damage, acetylcholinesterase (AChE activity, inflammatory markers and clinical symptoms in farmers exposed to organophosphorus pesticides to individuals that had no pesticide exposure. Materials and Methods: We conducted a cross-sectional survey with a total of 134 people. The subject group consisted of 67 farmers who were exposed to organophosphorus pesticides. The control group consisted of 67 people without any contact with pesticides matched with the subject group in terms of age, gender, and didactics. Oxidative DNA damage, the activities of AChE, interleukin-6 (IL6, IL10 and C-reactive protein (CRP in serum were measured and clinical examinations conducted in order to register all clinical signs. Results: Compared with the control group, substantial gains were observed in the farmers’ levels of oxidative DNA damage, IL10 and CRP. There was significantly less AChE activity in farmers exposed to organophosphorus pesticides. The levels of IL6 in both groups did not significantly differ. Conclusion: The outcomes show that exposure to organophosphorus pesticides may cause DNA oxidative damage, inhibit AChE activity and increase the serum levels of inflammatory markers. Using biological materials instead of chemical pesticides and encouraging the use of safety equipment by farmers are some solutions to the adverse effects of exposure to organophosphorous pesticides.

  2. Comparative Toxicological Study between Exposed and Non-Exposed Farmers to Organophosphorus Pesticides

    Science.gov (United States)

    Taghavian, Fariba; Vaezi, Gholamhassan; Abdollahi, Mohammad; Malekirad, Ali Akbar

    2016-01-01

    Objective The purpose of this work was to compare DNA damage, acetylcholinesterase (AChE) activity, inflammatory markers and clinical symptoms in farmers exposed to organophosphorus pesticides to individuals that had no pesticide exposure. Materials and Methods We conducted a cross-sectional survey with a total of 134 people. The subject group consisted of 67 farmers who were exposed to organophosphorus pesticides. The control group consisted of 67 people without any contact with pesticides matched with the subject group in terms of age, gender, and didactics. Oxidative DNA damage, the activities of AChE, interleukin-6 (IL6), IL10 and C-reactive protein (CRP) in serum were measured and clinical examinations conducted in order to register all clinical signs. Results Compared with the control group, substantial gains were observed in the farmers’ levels of oxidative DNA damage, IL10 and CRP. There was significantly less AChE activity in farmers exposed to organophosphorus pesticides. The levels of IL6 in both groups did not significantly differ. Conclusion The outcomes show that exposure to organophosphorus pesticides may cause DNA oxidative damage, inhibit AChE activity and increase the serum levels of inflammatory markers. Using biological materials instead of chemical pesticides and encouraging the use of safety equipment by farmers are some solutions to the adverse effects of exposure to organophosphorous pesticides. PMID:27054123

  3. Prevalencia de foramen oval permeable en pacientes con accidente cerebrovascular o accidente isquémico transitorio criptogénicos

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    Alejandro E. Contreras

    2009-01-01

    Full Text Available RESUMENIntroducciónEl foramen oval permeable (FOP se encuentra en alrededor de la cuarta parte de la población general. Pese a que su hallazgo no tiene repercusiones clínicas y no requiere tratamiento,se reconoce como una posible causa de accidente cerebrovascular (ACV criptogénico.ObjetivoConocer la prevalencia de FOP en pacientes estudiados por ACV o crisis isquémicas transitorias(CIT criptogénicos.Material y métodosSe analizaron retrospectivamente los ecocardiogramas transesofágicos de pacientes con ACVo CIT criptogénicos derivados para la evaluación de fuentes embolígenas. Se definió FOP alpasaje de una o más burbujas dentro de los tres primeros latidos luego de la opacificación dela aurícula derecha. Se definió aneurisma del septum interauricular (ASA a la excursióndel septum hacia la aurícula derecha o izquierda de 10 mm o más.ResultadosSe evaluaron 43 pacientes, edad promedio 59,6 ± 16,9 años, 41,9% mujeres. Se halló FOPen 13 pacientes (30,2% - IC 95% 15% a 44%, de los cuales 7 (16,3% del total de la poblaciónpresentaban FOP grande. Hubo 6 casos de ASA (14%, todos asociados con FOP y en 4 deellos (66% el FOP era grande.ConclusionesLa prevalencia de FOP en pacientes con ACV o CIT criptogénicos es del 30% y en uno decada tres de ellos se asocia con aneurisma del septum interauricular.REV ARGENT CARDIOL 2009;77:493-495.

  4. Multiple simultaneous intracerebral hemorrhages following accidental massive lumbar cerebrospinal fluid drainage: Case report and literature review

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    Ruiz-Sandoval Jose

    2006-01-01

    Full Text Available Multiple simultaneous intracerebral hemorrhages (ICH are uncommon. We report the case of an 80-year-old woman with previous diagnosis of normal pressure hydrocephalus and who was brought to our hospital with altered mental status and urinary incontinence. Medical history of hypertension, hematological disorders or severe head trauma was absent. Platelet count and coagulation profile were unremarkable. An initial head computed tomography (CT showed sulcal enlargement and ventricular dilatation, but no evidence of ICH. A tap test indicated as a guide to case selection for shunt surgery accidentally resulted in cerebrospinal fluid (CSF overdrainage. The patient presented sudden neurological deterioration, with sluggishly responsive pupils and generalized tonic-clonic seizures. A new head CT demonstrated multiple supra and infratentorial ICH. The patient became comatose and had a fatal course. Hence, CSF overdrainage may either cause or precipitate multiple simultaneous ICHs, affecting both the infratentorial and supratentorial regions.

  5. Accidental permutation symmetries as a test for Grand Unification: the supersymmetric $SU(5)$ case

    CERN Document Server

    Fichet, Sylvain

    2016-01-01

    Unification of matter fields implies the existence of accidental permutation symmetries, which potentially remain immune to large quantum corrections up to the TeV scale. We investigate the case of a supersymmetric $SU(5)$ grand unified theory, where such a permutation symmetry is present in the up-type squark sector. We present a variety of tests allowing to challenge the $SU(5)$ hypothesis based on the observation of squarks at the LHC. These tests appear as relations among observables involving flavour-violating or chirality-flipping decays of squarks. Moreover, they rely on top-polarimetry and charm-tagging. As an example, we discuss the application to the scenario of Natural Supersymmetry, while more examples can be found in the related journal publications.

  6. 'Battered pets': features that raise suspicion of non-accidental injury.

    Science.gov (United States)

    Munro, H M; Thrusfield, M V

    2001-05-01

    A study of veterinarians' perceptions, and experience, of non-accidental injury (NAI) to pets was undertaken using an anonymous questionnaire distributed to a random sample of 1000 small animal practitioners in the UK. NAI was acknowledged by 91.3 per cent (95 per cent confidence interval, 88.2 to 93.9 per cent) of the 404 respondents who returned questionnaires, of whom 48.3 per cent (95 per cent confidence interval, 43.4 to 53.1 per cent) had either suspected or seen NAI. Four hundred and forty-eight cases were documented, predominantly in dogs (243) and cats (182). Factors either raising suspicion, or facilitating recognition, of NAI included: implication of a particular person, features of the history, referral agency involvement, behaviour of the owner and/or the animal, nature of the injuries, and socioeconomic class of owners. Additionally, sexual abuse and suspected cases of Munchausen syndrome by proxy were recorded.

  7. Cardiac thrombus developing after an accidental high-voltage electric shock in a child.

    Science.gov (United States)

    Akın, Alper; Bilici, Meki; Demir, Fikri; Gözü Pirinççioğlu, Ayfer; Yavuz, Celal

    2015-01-01

    Electric shock is a condition that may affect various organ systems and potentially cause death. Cardiac findings vary from asymptomatic mild injury to fatal myocardial involvement. Herein we present a five-year-old boy with a cardiac thrombus developing after an accidental electrical shock. Cardiac arrhythmias and evidence of ischemia have been reported after electric shock; we were, however, unable to identify an earlier case report of intracardiac thrombosis related to electric shock. Findings such as elevated cardiac enzymes and systolic dysfunction, which indicate myocardial damage following electric shock, were present in our patient. We think that the cardiac thrombus might have resulted from the myocardial damage and the slowed intracardiac blood flow related to systolic dysfunction. As the thrombus was thought to have been formed through known mechanisms, it was treated traditionally. However, further data regarding the etiology and management of such thrombi is needed.

  8. El seguro de accidentes personales en Colombia y su visión jurisprudencial.

    Directory of Open Access Journals (Sweden)

    Fabio Bonilla

    2003-01-01

    Full Text Available Un recorrido a través de 25 años de jurisprudencia colombiana, permite al autor exponer y comentar la posición de la jurisprudencia nacional en torno a la definición de accidente y la distribución de la carga probatoria en las pólizas de seguro de riesgos accidentales. Se destaca este artículo por poner de presente el contraste existente entre el derecho colombiano y el de los países europeos en lo referido a la definición del riesgo en este tipo de pólizas, con base en requerimientos de intencionalidad por parte del tercero que con su intervención da lugar al siniestro.

  9. Complications following an accidental sodium hypochlorite extrusion: A report of two cases

    Science.gov (United States)

    Bosch-Aranda, María L.; Canalda-Sahli, Carlos; Gay-Escoda, Cosme

    2012-01-01

    Sodium hypochlorite (NaOCl) is the most commonly used solution in root canal treatments, as it is a low-cost method that displays a very effective antimicrobial activity against microbiota of infected root canals. However, this solution can cause complications especially due to its cytotoxic features. When this solution is injected into the adjacent tissues, the patient usually experiences intense pain, and an urgent treatment should be implemented in order to prevent a long-term sequelae. This paper describes the clinical features of two patients that experienced an accidental extrusion of NaOCl after endodontic treatment of varying severity and with different treatments. Furthermore, it shows the long-term neurologic injuries that this type of accidents may cause and a treatment protocol for these situations will be suggested. Key words:Nerve damage, root canal irrigation, root canal treatment, sodium hypochlorite. PMID:24558554

  10. Accidental $\\xi$-scaling as a signature of nuclear effects at x $>$ 1

    CERN Document Server

    Benhar, O

    1995-01-01

    We propose an interpretation of the \\xi-scaling behavior of nuclear structure functions observed at Bjorken x>1 and Q^2 \\lesssim 4 \\, {\\rm (GeV/c)^2}. We show that at \\xi \\gtrsim 1, \\xi-scaling might arise accidentally because of the approximate cancellation of two different Q^2-dependent effects, namely Final State Interactions and the effects implicit in the choice of the scaling variable \\xi. We provide a new convolution formula for the nuclear structure function in terms of \\xi and make predictions for the kinematical regions where Final State Interactions are expected to be small and the suggested balancing of scaling violations is expected to break down. Our analysis is aimed at the final goal of clarifying the range of applicability of local duality ideas in nuclei.

  11. Necrotizing fasciitis due to Streptococcus mitis caused by accidental human bite.

    Science.gov (United States)

    Bastug, Aliye; Kislak, Sumeyye; Mutlu, Nevzat Mehmet; Akcaboy, Zeynep Nur; Koksal, Asude; Sertcelik, Ahmet; Ünlü, Ramazan Erkin; Akinci, Esragul; Bodur, Hurrem

    2016-01-31

    Human bite wounds are more prone to infection than animal bites, which may cause necrotizing soft tissue infections such as myositis, fasciitis. Both aerobic and anaerobic microorganisms may be responsible, including Streptococcus spp., Staphylococcus aureus, Peptostreptococcus spp. Necrotizing fasciitis is characterized by serious tissue destruction and systemic toxicity with high morbidity and mortality. We report a patient with Streptococcus mitis associated necrotizing fasciitis on the upper extremity resulting from an accidental human bite, which caused nearly fatal infection. Prophylactic antibiotic treatment should be given after a human bite to prevent infection. If the infection signs and symptoms develop, rapid diagnosis, appropriate antibiotic and surgical therapy should be administered immediately. Streptococcus mitis is a viridans streptococcus, usually known as a relatively benign oral streptococcus. To our knowledge, this is the first necrotizing fasciitis case due to Streptococcus mitis after human bite.

  12. Estimating accidental pollutant releases in the built environment from turbulent concentration signals

    Science.gov (United States)

    Ben Salem, N.; Salizzoni, P.; Soulhac, L.

    2017-01-01

    We present an inverse atmospheric model to estimate the mass flow rate of an impulsive source of pollutant, whose position is known, from concentration signals registered at receptors placed downwind of the source. The originality of this study is twofold. Firstly, the inversion is performed using high-frequency fluctuating, i.e. turbulent, concentration signals. Secondly, the inverse algorithm is applied to a dispersion process within a dense urban canopy, at the district scale, and a street network model, SIRANERISK, is adopted. The model, which is tested against wind tunnel experiments, simulates the dispersion of short-duration releases of pollutant in different typologies of idealised urban geometries. Results allow us to discuss the reliability of the inverse model as an operational tool for crisis management and the risk assessments related to the accidental release of toxic and flammable substances.

  13. Accidental Continuous Releases from Coal Processing in Semi-Confined Environment

    Directory of Open Access Journals (Sweden)

    Bruno Fabiano

    2013-09-01

    Full Text Available Notwithstanding the enforcement of ATEX EU Directives (94/9/EC of 23 March 1994 and safety management system application, explosions in the coal sector still claim lives and cause huge economic losses. Even a consolidated activity like coke dry distillation allows the opportunity of preventing explosion risk connected to fugitive emissions of coke oven gas. Considering accidental releases under semi-confined conditions, a simplified mathematical approach to the maximum allowed gaseous build-up is developed on the basis of the intrinsic hazards of the released compound. The results will help identifying and assessing low rate release consequences therefore to set-up appropriate prevention and control measures. The developed methodology was tested at the real-scale and validated by numerical computational fluid dynamics (CFD simulations showing the effectiveness of the methodology to evaluate and mitigate the risk connected to confined hazardous releases.

  14. Two viable large scalar multiplet models with an accidental Z2 symmetry

    CERN Document Server

    Earl, Kevin; Logan, Heather E; Pilkington, Terry

    2013-01-01

    Models in which the Higgs sector is extended by a single scalar electroweak multiplet Z will possess an accidental global Z2 symmetry if Z has isospin T=5/2 (sextet) or 7/2 (octet) and carries the same hypercharge as the Standard Model Higgs doublet. This Z2 symmetry keeps the lightest (neutral) member of Z stable and has interesting implications for phenomenology. We determine the constraints on these models from precision electroweak measurements and Higgs boson decays to two photons. We compute the thermal relic density of the stable member of Z and show that, for masses below 1 TeV, it can make up at most 1% of the dark matter in the universe. We also show that current dark matter direct detection experiments do not constrain the models, but future ton-scale experiments will probe their parameter space.

  15. The accidental data scientist big data applications and opportunities for librarians and information professionals

    CERN Document Server

    Affelt, Amy

    2015-01-01

    Harvard Business Review recently named the data scientist described as a high-ranking professional with the training and curiosity to make discoveries in the world of Big Data as "the sexiest job of the 21st century." Librarians and information professionals have always worked with data in order to meet the information needs of their constituents, thus "Big Data" is not a new concept for them though it is spawning new approaches along with a language all its own. InThe Accidental Data Scientist, Amy Affelt shows information professionals how to leverage their skills and training to master emerging tools, techniques, and vocabulary; create mission-critical Big Data research deliverables; and discover rewarding new career opportunities by embracing their inner Data Scientist.

  16. Forensic aspects of paediatric fractures. Differentiating accidental trauma from child abuse

    Energy Technology Data Exchange (ETDEWEB)

    Bilo, Rob A.C. [Netherlands Forensic Institute, The Hague (Netherlands). Department of Pathology and Toxicology; Rijn, Rick R. van [Emma Childrens' s Hospital/Academic, Medical Center Amsterdam (Netherlands). Department of Radiology; Robben, Simon G.F. [Maastricht University Medical Center, Maastricht (Netherlands)

    2010-07-01

    Fractures are a common finding in children and it is estimated that 2.1% of all children will suffer at least one fracture before the age of 16. With young children in particular, the question may arise if this is related to child abuse. The aim of this book is to help physicians involved in child abuse cases to interpret radiological findings in light of the forensic circumstances under which they occurred. The authors present up-to-date literature related to the mechanisms underlying non-accidental cases of trauma. In this book not only the radiological findings in child-abuse are discussed, but more importantly, these findings are analyzed from a forensic perspective. Careful attention is paid to evidence regarding reported trauma mechanisms and their clinical outcome; for example, can a fall from a couch result in a femoral fracture, and if not, where is the supporting evidence? (orig.)

  17. El Cuerpo Militar de Sanidad en la Investigación de Accidentes Aéreos

    Directory of Open Access Journals (Sweden)

    F. Rios Tejada

    2012-12-01

    Full Text Available La investigación de un accidente o incidente aéreo puede ser simple o enormemente compleja. El proceso de investigación puede conducir a la elaboración de un informe directo y conciso o lo más frecuente, significa un largo camino de recopilación, análisis, estudio y finalmente la elaboración de posibles conclusiones. En este proceso, los aspectos médicos, psicológicos, ambientales, psicosociales o ergonómicos englobados en el término genérico de factores humanos cobran una especial relevancia, atribuyéndose hasta un 60-80% de causas directas o coadyuvantes al mismo. En este trabajo se revisan los antecedentes jurídicos y base legal en la que se apoya la Comisión para la investigación técnica de accidentes de aeronaves militares (CITAAM, así como sus atribuciones, organización y composición, sus funciones generales y más concretamente las encomendadas al vocal médico de la misma. Desde su creación en 1994, la experiencia acumulada ha sido enorme, haciéndose mención de algunos datos de interés estadístico pero señalando también la labor de formación realizada y su proyección nacional e internacional, sobre todo en el marco de la OTAN.

  18. Observations on increased accidental asphyxia deaths in infancy while cosleeping in the state of Maryland.

    Science.gov (United States)

    Li, Ling; Zhang, Yang; Zielke, Ron H; Ping, Yan; Fowler, David R

    2009-12-01

    The Office of the Chief Medical Examiner (OCME) has recorded a significant increase of accidental asphyxia deaths in infancy associated with cosleeping in the state of Maryland in 2003. A total of 102 infants died suddenly and unexpectedly during 2003 in the state of Maryland. Of the 102 infants, 46 (45%) were found cosleeping. The frequency of cosleeping among these 102 infants was 28% (29/102) for black infants and 15% (15/102) for white infants. Ten of the 46 cosleeping infant deaths (20%) were determined to be the result of accidental asphyxia, and 28 cosleeping infant deaths (59%) were classified as "undetermined" because the possibility of asphyxia due to overlay while cosleeping could not be ruled out. Only 21 cases were determined to be Sudden Infant Death Syndrome (SIDS), which is consistent with the continuous decline of SIDS death in Maryland since 1994. The age of asphyxiated cosleeping infants ranged from 15 days to 9 months. Nine out of the 10 asphyxia deaths were black infants. The most common sleeping location of the asphyxia infants was on a couch/sofa, followed by an adult bed. Crib availability was documented in all of the cosleeping cases. A majority (61%) of the cosleeping infants (28/46) had an available crib or bassinet at home and 9 out of 10 asphyxiated cosleeping infants had a crib at home at the time of the incident. This report focuses on the detailed scene investigation findings of infant victims who died of asphyxia while cosleeping. The shift of diagnosis in sudden infant death investigation is also addressed.

  19. The effectiveness of a multidisciplinary QI activity for accidental fall prevention: Staff compliance is critical

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    Ohde Sachiko

    2012-07-01

    Full Text Available Abstract Background Accidental falls among inpatients are a substantial cause of hospital injury. A number of successful experimental studies on fall prevention have shown the importance and efficacy of multifactorial intervention, though success rates vary. However, the importance of staff compliance with these effective, but often time-consuming, multifactorial interventions has not been fully investigated in a routine clinical setting. The purpose of this observational study was to describe the effectiveness of a multidisciplinary quality improvement (QI activity for accidental fall prevention, with particular focus on staff compliance in a non-experimental clinical setting. Methods This observational study was conducted from July 2004 through December 2010 at St. Luke’s International Hospital in Tokyo, Japan. The QI activity for in-patient falls prevention consisted of: 1 the fall risk assessment tool, 2 an intervention protocol to prevent in-patient falls, 3 specific environmental safety interventions, 4 staff education, and 5 multidisciplinary healthcare staff compliance monitoring and feedback mechanisms. Results The overall fall rate was 2.13 falls per 1000 patient days (350/164331 in 2004 versus 1.53 falls per 1000 patient days (263/172325 in 2010, representing a significant decrease (p = 0.039. In the first 6 months, compliance with use of the falling risk assessment tool at admission was 91.5% in 2007 (3998/4368, increasing to 97.6% in 2010 (10564/10828. The staff compliance rate of implementing an appropriate intervention plan was 85.9% in 2007, increasing to 95.3% in 2010. Conclusion In our study we observed a substantial decrease in patient fall rates and an increase of staff compliance with a newly implemented falls prevention program. A systematized QI approach that closely involves, encourages, and educates healthcare staff at multiple levels is effective.

  20. ACCIDENTAL SUBCUTANEOUS INJECTION OF VECURONIUM BROMIDE IN A PATIENT WITH BURNS

    Directory of Open Access Journals (Sweden)

    Usha Dev

    2014-10-01

    Full Text Available BACKGROUND AND OBJECTIVES: In patients with burn injury drug pharmacology will be altered and this poses special anaesthetic challenge when an subcutaneous injection of a non- depolarizing muscle relaxant occurs in such a patient. Small studies remain an important source of knowledge and hence this study aims to provide information on the anaesthetic management in a case of accidental subcutaneous injection of vecuronium bromide in a burns patient. PRESENTATION, DIAGNOSIS & MANAGEMENT: A 22 year young male with 4 days old hot water induced grade 1 burns involving 45% of body surface area was posted for burns dressing. Anaesthesia was induced with propofol and vecuronium bromide through an external jugular vein to aid tracheal intubation. As the patient was not anaesthetized even after 10 minutes routine check lead to the discovery of fullness at the tip of the intravenous catheter indicating an extravasation of the drugs. Hence the other external jugular vein was cannulated and the patient induced and intubated using propofol, sevoflurane, nitrous oxide and oxygen. The action of vecuronium outlasted the duration of surgery. So the patient continued to receive support of mechanical ventilation with nitrous oxide and oxygen. It took 130 minutes for the clinical signs of recovery from the muscle relaxant to manifest. He was then reversed & extubated with subsequent good recovery. CONCLUSION: Subcutaneous injection of these drugs poses problems of delayed onset of action and prolonged duration of action. In an inadvertent accidental subcutaneous 0.1 mg/kg vecuronium bromide injection in a patient with 4 day old 45% burns showed delayed onset action and prolonged neuromuscular blockade due to subcutaneous deposition of the drug which was managed with mechanical ventilation .The reported resistance to the action of NDMR drugs in patient with burns was not noticed here probably because of the age of the thermal injury.

  1. Imaging of accidental contamination with F-18-solution; a quick trouble-shooting procedure

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    Kalevi Kairemo

    2016-01-01

    Full Text Available To the best of our knowledge, imaging of accidental exposure to radioactive fluorine-18 (F-18 due to liquid spill has not been described earlier in the scientific literature. The short half-life of F-18 (t½=110 min, current radiation safety requirements, and Good Manufacturing Practice (GMP regulations on radiopharmaceuticals have restrained the occurrence of these incidents. The possibility of investigating this type of incidents by gamma and positron imaging is also quite limited. Additionally, a quick and precise analysis of radiochemical contamination is cumbersome and sometimes challenging if the spills of radioactive materials are low in activity. Herein, we report a case of accidental F-18 contamination in a service person during a routine cyclotron maintenance procedure. During target replacement, liquid F-18 was spilled on the person responsible for the maintenance. The activities of spills were immediately measured using contamination detectors, and the photon spectrum of contaminated clothes was assessed through gamma spectroscopy. Despite protective clothing, some skin areas were contaminated, which were then thoroughly washed. Later on, these areas were imaged, using positron emission tomography (PET, and a gamma camera (including spectroscopy. Two contaminated skin areas were located on the hand (9.7 and 14.7 cm2, respectively, which showed very low activities (19.0 and 22.8 kBq respectively at the time of incident. Based on the photon spectra, F-18 was confirmed as the main present radionuclide. PET imaging demonstrated the shape of these contaminated hot spots. However, the measured activities were very low due to the use of protective clothing. With prompt action and use of proper equipments at the time of incident, minimal radionuclide activities and their locations could be thoroughly analyzed. The cumulative skin doses of the contaminated regions were calculated at 1.52 and 2.00 mSv, respectively. In the follow-up, no skin

  2. Study of the degradations caused by nuclear accidental conditions on a steel coating

    Energy Technology Data Exchange (ETDEWEB)

    Ayrinhac, F.; Terriol, J.M. [EDF Ceidre TEGG (France)

    2011-07-01

    The coatings used in nuclear power plants have an interest to make surfaces easily decontaminated and to protect carbon steel (liner and steelworks) from the corrosion. However, in the event of accidental conditions, in particular combining radiation and fast increase of temperature and pressure, these paintings must not constitute an uncontrolled source of debris which may block the safety related functions of core cooling. This experimental study reports the influence of thickness and colour of the withstanding of a steel coating during accidental conditions. The steel coating chosen has been qualified for the liner containment of EDF new generation nuclear power plants (EPR). According to its data sheet, it is composed of an anti-corrosion primer (45 {mu}m), of an intermediate coat (same nature than the primer, 45 {mu}m) and a top coat (50 {mu}m). The system, applied using an conventional spray, was studied by optical and electronic microscopy. After gun airless application and drying, steel samples underwent an irradiation test, a LOCA test followed by a post-accident (100 C an d 100% HR during 10 days). Microscopic analysis by SEM and optical microscopy were carried out in order to evaluate and compare degradations of samples. In conclusion, whatever the color chosen or the thickness obtained, the primers and second coat ('internal layer') do not undergo significant evolution during the test. The greatest part of degradations is inflicted on the top coat. These degradations take the form of vacuums of two types, micro-porosity (few microns diameter) and surface blisters connected with internal spherical vacuums of size ranging between 8 and 50 {mu}m

  3. Individual Genetic Susceptibility

    Energy Technology Data Exchange (ETDEWEB)

    Eric J. Hall

    2008-12-08

    Risk estimates derived from epidemiological studies of exposed populations, as well as the maximum permissible doses allowed for occupational exposure and exposure of the public to ionizing radiation are all based on the assumption that the human population is uniform in its radiosensitivity, except for a small number of individuals, such as ATM homozygotes who are easily identified by their clinical symptoms. The hypothesis upon which this proposal is based is that the human population is not homogeneous in radiosensitiviry, but that radiosensitive sub-groups exist which are not easy to identify. These individuals would suffer an increased incidence of detrimental radiation effects, and distort the shape of the dose response relationship. The radiosensitivity of these groups depend on the expression levels of specific proteins. The plan was to investigate the effect of 3 relatively rare, high penetrate genes available in mice, namely Atm, mRad9 & Brca1. The purpose of radiation protection is to prevent! deterministic effects of clinical significance and limit stochastic effects to acceptable levels. We plan, therefore to compare with wild type animals the radiosensitivity of mice heterozygous for each of the genes mentioned above, as well as double heterozygotes for pairs of genes, using two biological endpoints: a) Ocular cataracts as an important and relevant deterministic effect, and b) Oncogenic transformation in cultured embryo fibroblasts, as a surrogate for carcinogenesis, the most relevant stochastic effect.

  4. Estructuración del diplomado en investigación de accidentes aéreos de la Fuerza Aérea Colombiana

    Directory of Open Access Journals (Sweden)

    Jean Paul Strong Flores

    2006-01-01

    Full Text Available Esta investigación tiene como objetivo la elaboración del diplomado en investigación de accidentes aéreos que suministrará las competencias necesarias para liderar las investigaciones de accidentes o incidentes aéreos. Esto en el marco de la educación continuada en investigación de accidentes aéreos permitirá a los oficiales de seguridad determinar con exactitud las causas de los accidentes, de tal forma que sea una medida correctiva para desarrollar destreza y habilidades en la investigación de accidentes.

  5. Analysis of reproductive function in persons exposed to chronic radiation

    Energy Technology Data Exchange (ETDEWEB)

    Kossenko, M.M.; Ostroumova, E.V.; Vyushkova, O.V. [Urals Research Center for Radiation Medicine, Chelyabinsk (Russian Federation)

    2000-05-01

    The purpose of the study was to analyze the reproductive function in individuals exposed to radiation in the riverside villages on the Techa in the Southern Urals. The exposure of the population, numbering 28000, occurred in 1950-1956 as a result of discharges into the river of radioactive wastes from the Mayak facility for processing weapon plutonium. The residents were exposed to chronic radiation, both external and internal. The range of exposure doses to gonads was sufficiently wide: 20-1270 mSv. However, the distribution of doses among the exposed individuals was ununiform, and the proportion of people whose dose was below 120 mGy accounted for 74%. The following characteristics of exposed women were analyzed: menstrual function, outcomes of pregnancy, birth rates, health status for newborns. The analysis of the menstrual function in exposed women showed that in persons exposed in childhood, menarche was registered at the age of 14.3 years, on the average (based on literature sources, menarche is attained at the age of 13 for unexposed population). The mean age at menopause was 47.9 years for exposed women (the respective mean value for Russia is 50.8 years). Pregnancy outcomes were analyzed in 9000 exposed women. The rate of medical and criminal abortions was estimated as 79 per 100 labors. The rate of spontaneous abortions for exposed women was slightly higher, 3.11%, than for controls, 2.30%; these difference, however, were statistically insignificant. The total loss of fetus or neonate (unfavorable outcomes of pregnancy: spontaneous abortions, stillbirths, early neonatal death) was estimated to be 4.58% at zero dose. Exposure to gonads at the dose 1 Sv, estimated using the above-indicated method, yielded 3% of additional unfavorable outcomes of pregnancy. It was shown, based on the analysis of birth rates for the Techa Cohort that they had not undergone any essential changes over the first 25 years of exposure compared to the respective coefficients for

  6. Perfiles resilientes y calidad de vida en personas con discapacidad sobrevenida por accidentes de tráfico

    Directory of Open Access Journals (Sweden)

    Raquel Suriá Martínez

    2015-09-01

    Conclusión: Esto sugiere la necesidad de profundizar en el conocimiento de la resiliencia y en el diseño de programas que incrementen la calidad de vida de las personas con discapacidad tras un accidente de tráfico.

  7. Accidental and deliberate microbiological contamination in the feed and food chains — How biotraceability may improve the response to bioterrorism

    DEFF Research Database (Denmark)

    Knutsson, Rickard; van Rotterdam, Bart; Fach, Patrick

    2011-01-01

    A next frontier of the global food safety agenda has to consider a broad spectrum of bio-risks, such as accidental and intentional contaminations in the food and feed chain. In this article, the background for the research needs related to biotraceability and response to bioterrorism incidents ar...

  8. Notificación de accidentes y enfermedades laborales al Ministerio de Trabajo. Perú 2010-2014

    Directory of Open Access Journals (Sweden)

    Christian R Mejia

    Full Text Available Con el objetivo de determinar las tendencias de los accidentes y enfermedades laborales notificadas al Ministerio de Trabajo del Perú, se realizó un estudio descriptivo de datos secundarios, con los reportes extraídos de los boletines mensuales desde septiembre de 2010 a diciembre de 2014. Se notificaron a nivel nacional 54 596 accidentes laborales no mortales, las tasas de los accidentes laborales no mortales por millón de habitantes aumentaron en el período 2011- 2013 (296,5 el 2011, 955,9 el 2012 y 1176,3 el 2013, disminuyendo en el 2014 (878,9. Hubieron 674 accidentes mortales, cuyas tasas se incrementaron entre el 2011-2012 y se redujeron entre el 2013-2014. Se reportaron 346 enfermedades laborales, las más frecuentes fueron los casos de hipoacusia (77, enfermedades por posturas inadecuadas (57 y dermatitis alérgica (44; los reportes se redujeron de 6,9 en el 2011 a 2,3 en el 2014. Los reportes de enfermedades laborales fueron disminuyendo, lo que podría indicar una subnotificación importante

  9. Method for calibration of the NaI(Tl) 3''x 3'' detector for in vivo measurements in patients undergoing radioiodine therapy and occupationally exposed individuals to {sup 131}I; Metodologia para calibracao do detector de NaI(Tl) 3''x 3''para medicoes in vivo em pacientes submetidos a radioiodoterapia e individuos ocupacionalmente expostos ao {sup 131}I

    Energy Technology Data Exchange (ETDEWEB)

    Xavier, A.C.S.; Oliveira, M.L.; Lima, F.F.; Lima, F.R.A. [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil); Lacerda, I.V.B., E-mail: line_c7@hotmail.com [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil); Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Programa de Pos-Graduacao em Tecnologias Energeticas e Nucleares

    2012-07-01

    According to studies by the Instituto Nacional do Cancer (INCA), in recent years the incidence of thyroid cancer is the fastest growing in relation to other types. For the treatment is required the exact amount of {sup 131}I isotope for each patient resulting on manipulation of this isotope in nuclear medicine services by individuals who are considered occupationally exposed (OEI). This work aims to establish the methodology for calibration of the detection system used to determine the therapeutic activity of {sup 131}I, required to release the desired absorbed dose in the thyroid gland, as well as in monitoring OEI that manipulate this radionuclide in nuclear medicine services. This is one of the early stages of implementation of Laboratorio de Dosimetria Interna at the Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE). The detector system consists of a NaI(Tl) 3'' x 3'' associated with electronic devices and Genie 2000 software. Sources of {sup 60}Co, {sup 137}Cs and {sup 133}Ba were utilized for calibration. Firstly, measurements were carried out in non-exposed individuals for obtaining the Minimum Detectable Activity (MDA) and then Minimum Detectable Incorporation (MDI) and the Minimum Effective Dose Detectable (MEDD) were determined through biokinetic models provided by the ICRP 67 and edited by the AIDE software version 6 to workers and patients. The values for the MEDD were 3.57 x 10{sup -2} mSv, 5.56 x 10{sup -2} mSv and 10.7 x 10{sup -2} mSv to 1, 7 and 14 days, respectively, after {sup 131}I incorporation by workers. As for patients, MEDD were 3.44 x 10{sup -2} mSv, 5.63 x 10{sup -2} mSv and 10.9 x 10{sup -2} mSv for the same periods of time. It is applicable to the assessment of dose OEI, since it presents less than the recommended minimum of 1 mSv. The technique also has adequate sensitivity for evaluation of activity present in the thyroid of patients with thyroid dysfunction. (author)

  10. Factors Influencing the Intended Likelihood of Exposing Sexual Infidelity.

    Science.gov (United States)

    Kruger, Daniel J; Fisher, Maryanne L; Fitzgerald, Carey J

    2015-08-01

    There is a considerable body of literature on infidelity within romantic relationships. However, there is a gap in the scientific literature on factors influencing the likelihood of uninvolved individuals exposing sexual infidelity. Therefore, we devised an exploratory study examining a wide range of potentially relevant factors. Based in part on evolutionary theory, we anticipated nine potential domains or types of influences on the likelihoods of exposing or protecting cheaters, including kinship, strong social alliances, financial support, previous relationship behaviors (including infidelity and abuse), potential relationship transitions, stronger sexual and emotional aspects of the extra-pair relationship, and disease risk. The pattern of results supported these predictions (N = 159 men, 328 women). In addition, there appeared to be a small positive bias for participants to report infidelity when provided with any additional information about the situation. Overall, this study contributes a broad initial description of factors influencing the predicted likelihood of exposing sexual infidelity and encourages further studies in this area.

  11. Resilience among Children Exposed to Domestic Violence: The Role of Risk and Protective Factors

    Science.gov (United States)

    Martinez-Torteya, Cecilia; Bogat, G. Anne; von Eye, Alexander; Levendosky, Alytia A.

    2009-01-01

    Individual and family characteristics that predict resilience among children exposed to domestic violence (DV) were examined. Mother-child dyads (n = 190) were assessed when the children were 2, 3, and 4 years of age. DV-exposed children were 3.7 times more likely than nonexposed children to develop internalizing or externalizing problems.…

  12. Evaluation of chromosome aberration frequency instable in individual groups residents at the municipality of Monte Alegre, Para, Brazil, exposed to radon; Avaliacao da frequencia de aberracoes cromossomicas instaveis em grupos de individuos residentes no municipio de Monte Alegre - PA expostos diferencialmente ao radonio

    Energy Technology Data Exchange (ETDEWEB)

    Yunes, Samira Nogarol

    2010-07-01

    The municipality of Monte Alegre is a region that presents natural radiation high due to the presence of the radionuclide uranium ({sup 238}U) in its soil, which through its decay gives rise to element Rn, a gas. The radioactivity of the rocks has become a problem for the population of Monte Alegre, from the moment when the radioactive material began to be used in the construction of houses and paving of streets. Among all bio markers related to environmental exposures and its biological effects, the chromosomal aberrations are considered good bio markers as predictors of the risk of cancer. Studies suggest that the frequency of chromosomal aberrations may be related to the genetic instability individual and/or exposure to ionizing radiation. Our work aimed to evaluate the frequency of chromosomal aberrations in individuals in the region of high natural radioactivity in Monte Alegre-PA. As well as to correlate the cytogenetic analysis made in this study with the results of analysis of frequency of polymorphisms of genes of DNA repair carried out in another study that resulted in other dissertation. In accordance with the distribution of the data obtained in characterizing environmental radiological and in the calculation of dose, were chosen residents of homes with more and less exposure to radiation. The samples of peripheral blood of 85 individuals of the resident population of the region of Monte Alegre - PA were collected and examine provided two slides for individual was performed to verify the quality of the sample. Through this evaluation we decide that 33% of the material collected, or is, samples of 28 individuals were in suitable conditions for analysis of the frequency of chromosomal aberrations. After the collections lymphocytes present in the sample were cultivated in accordance with the methodology proposed for obtaining of cells in metaphase. were analyzed 6,177 metaphases of 28 individuals among which were found dicentric chromosomes 4 and 19

  13. Advances in treating exposed fractures.

    Science.gov (United States)

    Nogueira Giglio, Pedro; Fogaça Cristante, Alexandre; Ricardo Pécora, José; Partezani Helito, Camilo; Lei Munhoz Lima, Ana Lucia; Dos Santos Silva, Jorge

    2015-01-01

    The management of exposed fractures has been discussed since ancient times and remains of great interest to present-day orthopedics and traumatology. These injuries are still a challenge. Infection and nonunion are feared complications. Aspects of the diagnosis, classification and initial management are discussed here. Early administration of antibiotics, surgical cleaning and meticulous debridement are essential. The systemic conditions of patients with multiple trauma and the local conditions of the limb affected need to be taken into consideration. Early skeletal stabilization is necessary. Definitive fixation should be considered when possible and provisional fixation methods should be used when necessary. Early closure should be the aim, and flaps can be used for this purpose.

  14. Quenched Reinforcement Exposed to Fire

    DEFF Research Database (Denmark)

    Hertz, Kristian Dahl

    2006-01-01

    Idealized data are derived for the tensile strength of quenched and tempered prestressing steel and of quenched and self-tempered reinforcing bars for fire safety design. 0.2% stresses are derived as a function of the maximum temperature and in addition, 2.0% stresses are provided. A strain of 2.......0% is seldom found in “slack” (not prestressed) reinforcement, but 2.0% stresses might be relevant for reinforcement in T shaped cross sections and for prestressed structures, where large strains can be applied. All data are provided in a “HOT” condition during a fire and in a “COLD” condition after a fire....... The COLD condition is relevant for analyses of residual load bearing capacity of a structure after a fire exposure. It is also relevant for analyses of concrete structures exposed to fully developed fire courses. The reason is that compression zones of concrete are always the weakest in the cooling phase...

  15. Some thoughts on the compliance with intervention levels in an area contaminated by an accidental deposition of caesium 137; Reflexions sur le respect des niveaux d`intervention dans un territoire contamine par un depot accidentel de cesium 137

    Energy Technology Data Exchange (ETDEWEB)

    Maubert, H.; Robeau, D.; Renaud, P. [CEA Centre d`Etudes de Cadarache, 13 - Saint-Paul-lez-Durance (France); Linge, I.; Pavlovski, O.; Ossipiants, I. [Institut de Surete Nucleaire, Moscou (Russian Federation)

    1995-10-01

    After a nuclear accident leading to an important radionuclide deposition, the responsible authorities are faced to the question of complying with intervention levels. These regulations may be expressed as mass activities in foodstuffs, or individual doses for the populations. A situation of acute caesium 137 contamination of the environment was played in 1993 during a French and Russian joint crisis exercise. In answering the questions from the administration, the experts examined the conditions allowing agricultural practices (1) according to a set of intervention levels in foodstuffs, and (2) how that was compatible with a recommendation relative to an individual dose for the populations of 1 mSv/y, although this limit is applicable in normal conditions and is not intended for post-accidental situations. (authors). 9 refs., 2 figs., 3 tabs.

  16. Attention Deficit Hyperactivity Disorder Symptoms, Sleepiness and Accidental Risk in 36140 Regularly Registered Highway Drivers

    Science.gov (United States)

    Philip, Pierre; Micoulaud-Franchi, Jean-Arthur; Lagarde, Emmanuel; Taillard, Jacques; Canel, Annick; Sagaspe, Patricia; Bioulac, Stéphanie

    2015-01-01

    Background Attention Deficit Hyperactivity Disorder (ADHD) is a frequent neurodevelopmental disorder that increases accidental risk. Recent studies show that some patients with ADHD can also suffer from excessive daytime sleepiness but there are no data assessing the role of sleepiness in road safety in patients with ADHD. We conducted an epidemiological study to explore sleep complaints, inattention and driving risks among automobile drivers. Methods and Findings From August to September 2014, 491186 regular highway users were invited to participate in an Internet survey on driving habits. 36140 drivers answered a questionnaire exploring driving risks, sleep complaints, sleepiness at the wheel, ADHD symptoms (Adult ADHD Self-Report Scale) and distraction at the wheel. 1.7% of all drivers reported inattention-related driving accidents and 0.3% sleep-related driving accidents in the previous year. 1543 drivers (4.3%) reported ADHD symptoms and were more likely to report accidents than drivers without ADHD symptoms (adjusted OR = 1.24, [1.03–1.51], p 15) versus 3.2% of drivers without ADHD symptoms and 20.5% reported severe sleepiness at the wheel versus 7.3%. Drivers with ADHD symptoms reported significantly more sleep-related (adjusted OR = 1.4, [1.21–1.60], p < .0001) and inattention-related (adjusted OR = 1.9, [1.71–2.14], p<0001) near misses than drivers without ADHD symptoms. The fraction of near-misses attributable to severe sleepiness at the wheel was 4.24% for drivers without ADHD symptoms versus 10,35% for drivers with ADHD symptoms. Conclusion Our study shows that drivers with ADHD symptoms have more accidents and a higher level of sleepiness at the wheel than drivers without ADHD symptoms. Drivers with ADHD symptoms report more sleep-related and inattention-related near misses, thus confirming the clinical importance of exploring both attentional deficits and sleepiness at the wheel in these drivers. Road safety campaigns should be improved to

  17. Transferencia del aprendizaje motor en pacientes con antecedentes de accidente cerebrovascular: serie de casos

    Directory of Open Access Journals (Sweden)

    Karen Castro-Medina

    2015-04-01

    Full Text Available Antecedentes. La rehabilitación es un proceso de reaprendizaje motor, que mejora el desempeño en términos de adquisición de nuevas habilidades y adaptación o refinamiento de habilidades aprendidas previamente. A pesar de este conocimiento, existen, considerablemente, pocos estudios que describan el aprendizaje motor después de un accidente cerebrovascular (ACV y la relevancia del mismo en los procesos de rehabilitación y recuperación. Objetivo. Describir la transferencia del aprendizaje motor en pacientes con antecedentes de accidente cerebrovascular después de un tratamiento con procedimientos de reeducación funcional. Materiales y métodos. Se realizó un estudio descriptivo de dos casos con pacientes que recibieron tratamiento fisioterapéutico ambulatorio con los principios de reeducación funcional desarrollados en el Hospital de las Clínicas de la Universidad de São Paulo (Brasil, entre los meses de agosto y octubre de 2013. La transferencia del aprendizaje motor se determinó según los resultados obtenidos en la evaluación de balance funcional (Mini-BESTest. Se evaluó el test antes y después del tratamiento y se compararon los resultados para determinar el porcentaje de mejora. Resultados. En los dos casos se observó mejora clínica en el desempeño de la evaluación de balance funcional Mini-BESTest con un porcentaje de mejora entre el 21% y el 41%. Conclusión. Existen pocos hallazgos literarios que describen el mantenimiento de la capacidad de aprendizaje motor en pacientes con antecedentes de ACV. Este estudio reportó la capacidad para transferir el aprendizaje motor a una habilidad motora no aprendida (balance en dos casos, con base en la mejoría clínica del desempeño motor en el test aplicado.

  18. Enfermedad preexistente, agravamiento y/o accidente de trabajo: análisis de 10 casos clínicos

    Directory of Open Access Journals (Sweden)

    Ana M.ª González Onetti

    2014-01-01

    Full Text Available En nuestro centro asistencial se han atendido en el año 2012, 1.304 primeras asistencias, de las cuales 85 fueron consideradas no accidente de trabajo/enfermedad profesional. Hemos elegido al azar 10 casos clínicos donde existió discrepancia por parte del paciente cuando los servicios médicos determinaron que la patología que sufría el paciente no era accidente de trabajo y/o agravamiento por lo que se derivó a su médico de atención primaria quien emitió parte de baja por contingencias comunes y se inició determinación de contingencias ante el INSS por parte del Servicio Andaluz de Salud. En 7 de los casos existió discrepancia entre los inspectores médicos del INSS y los servicios médicos de la mutua, en 3 de ellos se consideraron enfermedad común al existir enfermedad preexistente. De los casos analizados comprobamos que no existían criterios unificados, claros y precisos entre enfermedad preexistente, agravamiento y/o accidente de trabajo dependiendo del médico evaluador y/o médico de la mutua determinar si era o no accidente de trabajo. Si no existían antecedentes médicos por el SAS y/o bajas previas por ITCC por la misma patología o similar el INSS determino siempre la contingencia como accidente de trabajo. El tiempo medio de los 10 casos analizados entre el inicio de la determinación de contingencias y la comunicación de la resolución por parte del INSS fue de 240 días. De los 7 casos que fueron accidente de trabajo, 6 seguían en situación de baja laboral y un caso se encontraba curado e incorporado a su puesto de trabajo.

  19. The effect of a non-steroidal anti-inflammatory drug on two important predictors for accidental falls: postural balance and manual reaction time. A randomized, controlled pilot study.

    Science.gov (United States)

    Hegeman, Judith; Nienhuis, Bart; van den Bemt, Bart; Weerdesteyn, Vivian; van Limbeek, Jacques; Duysens, Jacques

    2011-04-01

    Accidental falls in older individuals are a major health and research topic. Increased reaction time and impaired postural balance have been determined as reliable predictors for those at risk of falling and are important functions of the central nervous system (CNS). An essential risk factor for falls is medication exposure. Amongst the medications related to accidental falls are the non-steroidal anti-inflammatory drugs (NSAIDs). About 1-10% of all users experience CNS side effects. These side effects, such as dizziness, headaches, drowsiness, mood alteration, and confusion, seem to be more common during treatment with indomethacin. Hence, it is possible that maintenance of (static) postural balance and swift reactions to stimuli are affected by exposure to NSAIDs, indomethacin in particular, consequently putting older individuals at a greater risk for accidental falls. The present study investigated the effect of a high indomethacin dose in healthy middle-aged individuals on two important predictors of falls: postural balance and reaction time. Twenty-two healthy middle-aged individuals (59.5 ± 4.7 years) participated in this double-blind, placebo-controlled, randomized crossover trial. Three measurements were conducted with a week interval each. A measurement consisted of postural balance as a single task and while concurrently performing a secondary cognitive task and reaction time tasks. For the first measurement indomethacin 75 mg (slow-release) or a visually identical placebo was randomly assigned. In total, five capsules were taken orally in the 2.5 days preceding assessment. The second measurement was without intervention, for the final one the first placebo group got indomethacin and vice versa. Repeated measures GLM revealed no significant differences between indomethacin, placebo, and baseline in any of the balance tasks. No differences in postural balance were found between the single and dual task conditions, or on the performance of the dual task

  20. Accidental oropharyngeal impalement injury in children: A report of two cases

    Directory of Open Access Journals (Sweden)

    Hayaki Uchino

    2015-01-01

    Full Text Available Impalement injuries in children may be deeper and more complicated than anticipated. We experienced two cases of accidental impalement injuries, one was through the oral cavity and the other was to the neck. We review these cases and the management of these types of injuries. Case series. In case 1, a 20-month-old girl fell from the table with a toothbrush in her mouth. She was conscious, without any apparent neurologic or vascular injuries. Examination revealed a 2 mm laceration with a small hematoma in the right posterior pharyngeal wall. Contrast-enhanced computed tomography (CECT revealed an air tract penetrating between the mandibular ramus and cervical vertebrae, passing by the carotid sheath, and reaching under the skin of the right posterior neck. Surgical emphysema was extended from the pharynx to the mediastinum. In case 2, a 3-year-old girl fell while holding a pencil. Physical examination revealed a 5 mm laceration in front of her right ear lobe accompanied by a small hematoma. Her facial movement was asymmetric, and she could not close her right eye. CECT showed swelling of the right parotid gland with heterogeneous enhancement and free air just in front of the right carotid sheath, which suggested the object penetrated through the parotid gland. A diagnosis of peripheral facial nerve injury was made. Physicians need to be aware of the potentially life-threatening complications of impalement injuries in children, as well as the specific complications related to proximity to specific anatomic structures.

  1. Neuroimaging for non-accidental head injury in childhood: A proposed protocol

    Energy Technology Data Exchange (ETDEWEB)

    Jaspan, T.; Griffiths, P.D.; McConachie, N.S.; Punt, J.A.G

    2003-01-01

    Non-accidental head injury (NAHI) is a major cause of neurological disability and death during infancy. Radiological imaging plays a crucial role in evaluating craniospinal injury, both for guiding medical management and the forensic aspects of abusive trauma. The damage sustained is varied, complex and may be accompanied by an evolving pattern of brain injury secondary to a cascade of metabolic and physiological derangements. Regrettably, many cases are poorly or incompletely evaluated leading to diagnostic errors and difficulties in executing subsequent child care or criminal proceedings. It is evident, from cases referred to the authors, that imaging protocols for NAHI are lacking (or only loosely adhered to, if present) in many centres throughout the U.K. Future research in this field will also be hampered if there is a lack of consistent and reliable radiological data. There is no nationally agreed protocol for imaging NAHI. We propose such a protocol, based upon a wide experience in the medical management of child abuse and extensive involvement in the medicolegal aspects of NAHI. Jaspan, T., et al. (2003). Clinical Radiology58, 44--53.

  2. Accidental intoxication of the infant-juvenile population in households: profiles of emergency care

    Directory of Open Access Journals (Sweden)

    Jackeline Gonçalves Brito

    2015-06-01

    Full Text Available OBJECTIVE Analyzing profiles of intoxication and accidental poisoning of infant-juvenile population (0-24 years in the household, treated at a reference facility for Emergency and Primary Care, during the year 2013. METHOD A descriptive, cross-sectional study. Data were analyzed using Epi-Info, by way of simple and bivariate analyzes. The project was approved by the Research Ethics Committee (protocol 405.578. RESULTS There were 45 intoxications, with a prevalence of males (60.0%, aged 1-4 years (71.1%. Among children under one, there was a higher frequency of pesticide poisoning (66.6%, between the ages of 1-4 by cleaning products (34.4%, and between 5-9 years of age by pharmacological substances (66.6%. The primary assistance was provided only at health institutions, with hospital admissions in 24.4% of the cases. CONCLUSION The importance of prevention through legislation is evident, in order to ensure greater safety in packaging of various products, and community awareness to eliminate risks in the household environment.

  3. Game theory of pre-emptive vaccination before bioterrorism or accidental release of smallpox.

    Science.gov (United States)

    Molina, Chai; Earn, David J D

    2015-06-06

    Smallpox was eradicated in the 1970s, but new outbreaks could be seeded by bioterrorism or accidental release. Substantial vaccine-induced morbidity and mortality make pre-emptive mass vaccination controversial, and if vaccination is voluntary, then there is a conflict between self- and group interests. This conflict can be framed as a tragedy of the commons, in which herd immunity plays the role of the commons, and free-riding (i.e. not vaccinating pre-emptively) is analogous to exploiting the commons. This game has been analysed previously for a particular post-outbreak vaccination scenario. We consider several post-outbreak vaccination scenarios and compare the expected increase in mortality that results from voluntary versus imposed vaccination. Below a threshold level of post-outbreak vaccination effort, expected mortality is independent of the level of response effort. A lag between an outbreak starting and a response being initiated increases the post-outbreak vaccination effort necessary to reduce mortality. For some post-outbreak vaccination scenarios, even modest response lags make it impractical to reduce mortality by increasing post-outbreak vaccination effort. In such situations, if decreasing the response lag is impossible, the only practical way to reduce mortality is to make the vaccine safer (greater post-outbreak vaccination effort leads only to fewer people vaccinating pre-emptively).

  4. Failure Criteria for Evaluating Accidental Drops of Fuel Containers at INTEC

    Energy Technology Data Exchange (ETDEWEB)

    Miller, G. K.

    1998-10-01

    This report presents a failure criterion that has been developed for use in evaluating fuel containers at the Idaho Nuclear Technology and Engineering Center (INTEC) for accidental drop events. The criterion would typically be used in dynamic finite element analyses using the ABA-QUS/Explicit program. The failure criterion used in the past is generally considered to substantially underestimate the strength and ductility of the materials involved. The new criterion is intended to be more realistic, allowing for more accurate impact analyses. The criterion is based on the distortion energy theory, which is considered to be appropriate for the ductile materials typically used in fuel containers. Also addressed in development of the criterion were the effects of strain rate and hydrostatic stress. The importance of these factors, however, is highly dependent on the material used. Three materials specifically addressed in this study were stainless steel, aluminum, and lead. The criterion is presented in the form of guidelines and recommendations that are based on material data obtained from the literature. The most significant difference between these and the previous criterion is that ductile materials are allowed to strain to much higher levels before they are considered to fail.

  5. Clinical and ethical orientations in case of accidental ingestion of foreign body during dental treatment

    Directory of Open Access Journals (Sweden)

    Rhonan Ferreira da Silva

    2010-07-01

    Full Text Available Introduction:The passage of foreign bodies through the oropharynx during dental treatment is an accident that can be avoided in most cases,especially when the dentist adopts preventive measures such as using rubber dam or tying certain objects with dental floss. Objective:To emphasize the importance of avoiding the accident of ingesting foreign bodies during dental treatment and to guide the dentist on how to proceed,clinically and ethically, if the accident occurs.Case report:A minor female patient, unaccompanied,accidentally ingested a bur used for finishing a composite resin restoration during a dental treatment performed in the public service, due to a defect in the high-speed handpiece.The patient and their parents were informed of the accident,and the object was monitored radiographically until its elimination by natural means,with no reports of discomfort.Conclusion:It is the responsibility of the dentist to know and follow the necessary measures to avoid or solve complications from ingesting foreign bodies, since patient’s health and integrity must be protected. In addition, the dentist will also avoid possible ethical and legal demands when fulfilling his responsibilities as a health care professional.

  6. Biomechanical studies in an ovine model of non-accidental head injury.

    Science.gov (United States)

    Anderson, R W G; Sandoz, B; Dutschke, J K; Finnie, J W; Turner, R J; Blumbergs, P C; Manavis, J; Vink, R

    2014-08-22

    This paper presents the head kinematics of a novel ovine model of non-accidental head injury (NAHI) that consists only of a naturalistic oscillating insult. Nine, 7-to-10-day-old anesthetized and ventilated lambs were subjected to manual shaking. Two six-axis motion sensors tracked the position of the head and torso, and a triaxial accelerometer measured head acceleration. Animals experienced 10 episodes of shaking over 30 min, and then remained under anesthesia for 6h until killed by perfusion fixation of the brain. Each shaking episode lasted for 20s resulting in about 40 cycles per episode. Each cycle typically consisted of three impulsive events that corresponded to specific phases of the head's motion; the most substantial of these were interactions typically with the lamb's own torso, and these generated accelerations of 30-70 g. Impulsive loading was not considered severe. Other kinematic parameters recorded included estimates of head power transfer, head-torso flexion, and rate of flexion. Several styles of shaking were also identified across episodes and subjects. Axonal injury, neuronal reaction and albumin extravasation were widely distributed in the hemispheric white matter, brainstem and at the craniocervical junction and to a much greater magnitude in lower body weight lambs that died. This is the first biomechanical description of a large animal model of NAHI in which repetitive naturalistic insults were applied, and that reproduced a spectrum of injury associated with NAHI.

  7. The review of autopsy cases of accidental childhood deaths in Istanbul.

    Science.gov (United States)

    Yayci, Nesime; Pakis, Isil; Karapirli, Mustafa; Celik, Sefa; Uysal, Cem; Polat, Oguz

    2011-08-01

    Children are at increased risk for various causes of injury from accidents. Accidents are, by far, the leading cause of death among children and adolescents. The aim of this study is to evaluate the lethal childhood accidents in İstanbul by age groups. Reports of autopsies performed between 2001 and 2005 in the Morgue Department of the Council of Forensic. Medicine in Istanbul (n :16853) are examined retrospectively. 833 deaths from accidents in children aged 0-18 years are investigated into the study. The parameters of age, gender, types of accidents and causes of death are evaluated. The accidents account for 47.3% of the deaths among children aged 0-18 years. Of 833 cases, 601 (73%) are male and 232 (27%) are female. The female to male ratio is 1/2.6. The highest rate of death from accidents is at the group of 15-18 years. The primary causes of accidental childhood deaths are motor vehicle accidents (23.1%), followed by drowning (20,1%), poisoning (15.7%), and fall from height (15.5%). The incidence and types of trauma vary with socio-economic status and culture. İstanbul, where this study is conducted in, has approximately 3000 autopsy number annually. Therefore, it provides an important database.

  8. Multidetector Computed Tomography Imaging of Facial Trauma in Accidental Falls from Heights

    Energy Technology Data Exchange (ETDEWEB)

    Salonen, E.M.; Koivikko, M.P.; Koskinen, S.K. [Helsinki Medical Imaging Center, Dept. of Radiology, Toeoeloe Trauma Center, Helsinki Univ. Hospital, Helsinki (Finland)

    2007-04-15

    Purpose: To assess multidetector computed tomography (MDCT) findings in facial trauma in adults who accidentally fall from heights. Material and Methods: Of the MDCT scans of 2413 cases requested by emergency-room physicians for suspected facial injury, 155 (age 15.3-76.7, mean 42.0 years; 134 male, 21 female) met the criteria of falling from heights. These were reviewed by two researchers by consensus. Results: Of these 155, 118 (104 male, 14 female) had 247 fractures, while 37 had no fracture. The fractures were classified into 13 categories, the zygomatic complex being the region most frequently involved. Mean falling height, known in 132 of 155 cases, was 5.7 m (range 0.4-25) in all, 6.0 m (0.4-25) in those suffering a fracture, and 5.0 m (range 0.4-13) in those without a fracture. Patients with Le Fort II, Le Fort III, or frontal bone fractures had fallen higher and frequently had associated skull base fractures, but with considerable overlap in falling heights. Zygomatic arch and nasal bone fractures rarely occurred solitarily. Conclusion: In a fall-from-height injury, nasal bone and zygomatic arch fractures indicate the presence of more severe fractures. Height cannot solely predict injury probability. Clear sinus sign is a valuable aid in assessing midface trauma in falls from heights. Keywords: CT; face; trauma.

  9. Modeling acute health risks associated with accidental releases of toxic gases

    Energy Technology Data Exchange (ETDEWEB)

    Haskin, F.E.; Ding, C.; Summa, K.J. [Univ. of New Mexico, Albuquerque, NM (United States). Dept. of Chemical and Nuclear Engineering; Young, M. [Sandia National Labs., Albuquerque, NM (United States). Accident Analysis and Consequence Assessment Dept.

    1996-09-01

    CHEM{_}MACCS has been developed from the radiological accident consequence code, MACCS, to perform probabilistic calculations of potential off-site consequences of the accidental atmospheric release of hazardous chemicals. The principal phenomena considered in CHEM{_}MACCS are atmospheric transport, mitigative actions based on dose projection, dose accumulation by a number of pathways, and early and latent health effects. CHEM{_}MACCS provides the following capabilities: (1) statistical weather sampling data (8,760 hourly data points per year), (2) population dose and health effect risk calculations based on site-specific population data, (3) health effects calculations including the consideration of potential site specific mitigative actions (evacuation and shielding), and (4) modeling of multiple release segments. Three different sample problems are contained in this report to show how to use CHEM{_}MACCS. Three test problems are run to compare CHEM{_}MACCS and D2PC. The doses versus the downwind centerline distances from the source for the given doses are in very close agreement.

  10. Design of a monitoring network over France in case of a radiological accidental release

    Science.gov (United States)

    Abida, Rachid; Bocquet, Marc; Vercauteren, Nikki; Isnard, Olivier

    The Institute of Radiation Protection and Nuclear Safety (France) is planning the set-up of an automatic nuclear aerosol monitoring network over the French territory. Each of the stations will be able to automatically sample the air aerosol content and provide activity concentration measurements on several radionuclides. This should help monitor the French and neighbouring countries nuclear power plants set. It would help evaluate the impact of a radiological incident occurring at one of these nuclear facilities. This paper is devoted to the spatial design of such a network. Here, any potential network is judged on its ability to extrapolate activity concentrations measured on the network stations over the whole domain. The performance of a network is quantitatively assessed through a cost function that measures the discrepancy between the extrapolation and the true concentration fields. These true fields are obtained through the computation of a database of dispersion accidents over one year of meteorology and originating from 20 French nuclear sites. A close to optimal network is then looked for using a simulated annealing optimisation. The results emphasise the importance of the cost function in the design of a network aimed at monitoring an accidental dispersion. Several choices of norm used in the cost function are studied and give way to different designs. The influence of the number of stations is discussed. A comparison with a purely geometric approach which does not involve simulations with a chemistry-transport model is performed.

  11. Ileum perforation due to accidental chicken bone ingestion a rare cause of the acute abdomen

    Directory of Open Access Journals (Sweden)

    Doklestić Krstina S.

    2012-03-01

    Full Text Available Ingestion of foreign bodies is not an uncommon occurrence, but most of them will pass through the gastrointestinal tract without consequences. Complication such as perforation is rare. We present a case of small bowel perforation secondary to the accidental ingestion of a chicken bone. The patient presented with abdominal pain, constipation and vomiting. Clinical examination confirmed generalized abdominal tenderness and rebound tenderness. Abdominal radiography showed multiple dilated loops of small bowel, and abdominal ultrasound (US showed inflammatory changes on small bowel loops, with free fluid and fluid collection around intestinal loops. The patient underwent an emergency laparotomy. Intra operative findings revealed diffuse fibro purulent peritonitis with abscess between central small bowels loops. At about 60 cm from Bauchini valve we found a perforation of ileum at the anti-mesenteric site caused by a sharp chicken wishbone. The patient was treated with resection of the ileum segment (10 cm and primary end-to-end anastomosis. Even that intestinal perforation by a foreign body is rare, physicians should consider possibility of intestinal perforation by a foreign body in the differential diagnosis of acute abdomen in patients presenting with abdominal pain.

  12. Accidental infection of veterinary personnel with Mycobacterium tuberculosis at necropsy: a case study.

    Science.gov (United States)

    Posthaus, H; Bodmer, T; Alves, L; Oevermann, A; Schiller, I; Rhodes, S G; Zimmerli, S

    2011-05-05

    Mycobacterium tuberculosis is the main cause of human tuberculosis. Infection in companion animals is mainly acquired from close contact to a diseased human patient and hence rarely diagnosed in countries with low tuberculosis incidence rates. Therefore the general awareness of the disease might be low. Here we report the potential risk of infection for veterinary personnel with M. tuberculosis during the clinical and pathological examination of a dog with unexpected disseminated tuberculosis. The dog had presented with symptoms of a central nervous system disease; rapid deterioration prevented a complete clinical workup, however. Post-mortem examination revealed systemic mycobacteriosis, and M. tuberculosis was identified by PCR amplification of DNA extracts from paraffin-embedded tissue sections and spoligotyping. Contact investigations among the owners and veterinary personnel using an IFN-γ release assay indicated that the index dog did not infect humans during its lifetime. Serological and IFN-γ release assay results of one of two cats in direct contact with the index dog, however, suggested that transmission of M. tuberculosis might have occurred. Importantly, all three pathologists performing the necropsy on the dog tested positive. Accidental infection was most likely due to inhalation of M. tuberculosis containing aerosols created by using an electric saw to open the brain cavity. As a consequence routine necropsy procedures have been adapted and a disease surveillance program, including tuberculosis, has been initiated. Our results highlight the importance of disease awareness and timely diagnosis of zoonotic infectious agents in optimizing work safety for veterinary personnel.

  13. Accidental Interaction between PDZ Domains and Diclofenac Revealed by NMR-Assisted Virtual Screening

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    Kengo Kinoshita

    2013-08-01

    Full Text Available In silico approaches have become indispensable for drug discovery as well as drug repositioning and adverse effect prediction. We have developed the eF-seek program to predict protein–ligand interactions based on the surface structure of proteins using a clique search algorithm. We have also developed a special protein structure prediction pipeline and accumulated predicted 3D models in the Structural Atlas of the Human Genome (SAHG database. Using this database, genome-wide prediction of non-peptide ligands for proteins in the human genome was performed, and a subset of predicted interactions including 14 PDZ domains was then confirmed by NMR titration. Surprisingly, diclofenac, a non-steroidal anti-inflammatory drug, was found to be a non-peptide PDZ domain ligand, which bound to 5 of 15 tested PDZ domains. The critical residues for the PDZ–diclofenac interaction were also determined. Pharmacological implications of the accidental PDZ–diclofenac interaction are further discussed.

  14. Maternal and infant characteristics associated with accidental suffocation and strangulation in bed in US infants.

    Science.gov (United States)

    Carlberg, Michelle M; Shapiro-Mendoza, Carrie K; Goodman, Michael

    2012-11-01

    To identify maternal and infant characteristics associated with accidental suffocation and strangulation in bed (ASSB) in US infants. Using 2000-2002 US linked infant birth and death certificate cohort files, we compared ASSB deaths to survivors. Adjusted odds ratios (aOR) from logistic regression were used to analyze associations between selected maternal and infant characteristics and ASSB mortality. During 2000-2002, 1,064 infants died from ASSB, resulting in an ASSB mortality rate of 9.2 per 100,000 live births. Most ASSB deaths (71%) occurred before an infant reached 4 months old. Maternal factors associated with an increased risk of ASSB were younger age (using maternal age of 25-29 years as reference aOR 2.6 for mothers mortality risk. Younger, less educated, mulitparous, non-Hispanic black or American Indian women and their families who smoke during their pregnancy and deliver male or preterm infants, may need more intense safe sleeping education during the infant's first year of life, especially during the first 4 months of age.

  15. Fibroelastoma valvular aórtico como causa de accidente cerebrovascular embólico: Reporte de un caso

    OpenAIRE

    Bahamondes S,Juan Carlos; MERIÑO S,GUSTAVO; SALMAN A,JUAN; SILVA V,ABELARDO; MORA M,JAVIER

    2008-01-01

    Los tumores cardíacos son una causa rara de accidente cerebrovascular embólico. Comunicamos el caso de una paciente de 65 años quien debuta su historia con un accidente cerebrovascular. El estudio de fuente embólica con ecocardiografía transesofágica demostró un fibroelastoma de la válvula aórtica en el borde libre del velo no coronariano. El tumor fue extraído mediante circulación extracorpórea. El estudio anatomopatológico confirmó el diagnóstico y la paciente se encuentra en capacidad func...

  16. Accidental ingestion of an inter-occlusal device used for the restoration of occlusion: a case report.

    Science.gov (United States)

    Vasconcellos, Walison Arthuso; Braga, Neilor Mateus Antunes; Moretzsohn, Luciana Dias; Lanza, Marcos Daniel Septimio; Lanza, Marcos Dias; Rocha, Wellington Márcio dos Santos

    2014-09-01

    The accidental swallowing of prosthetic devices has been discussed in the relevant literature as an unusual, although ordinary, event in clinical practice. This article aims at reporting the ingestion of an inter-occlusal device used to restore the Vertical Dimension of Occlusion (VDO) which, during the ingestion of an analgesic pill, was accidentally swallowed. The patient was sent to the Clinics Hospital UFMG where, upon taking radiographs, the device was located in the upper third of the esophagus. The device was removed during an endoscopic exam with the help of forceps for removing foreign objects. Dealing with a relevant situation, one may conclude that patients who use removable intra-oral devices must take part in a reevaluation protocol in order to detect adaptation and retention of these devices, as well as proper instruction for the patient.

  17. Wandering Fish Bone: a Case of Pelvic Abscess due to Rectum Perforation Resulting from an Accidental Fish Bone Ingestion

    Directory of Open Access Journals (Sweden)

    Sirous Abbasi

    2010-09-01

    Full Text Available Fish bone is the most common foreign body that is ingested accidentally and can be caused gastrointestinal complications such as perforation, abstraction, and abscess. We describe a 75-year-old man who suffered from constipation, diarrhea, and fever and chills for 3 months. He had mild tenderness in hypogasteric region and also mild tenderness and swelling on anterior rectal wall and prostate upon clinical examination. The abdominal and pelvic sonography and CT scan findings suggested existence of abscess in the space of between bladder and rectum. The patient underwent laparotomy to drainage the pelvic abscess. The surgeon found a 6-cm fish bone which was embedded in the abscess. The presented case indicated the importance of accidental fish bone ingestion and its possible complications. In addition, the patients with abdominal pain, GI bleeding, and fever of unknown origin living in the seaside regions, the wandering fish bone as a differential diagnosis should be kept in mind.

  18. Análisis de las muertes por accidentes de tránsito en el municipio de Lanús, Argentina, 1998-2004

    Directory of Open Access Journals (Sweden)

    Guillermo Raúl Macías

    2010-01-01

    Full Text Available El objetivo del presente trabajo fue analizar el perfil sociodemográfico de las muertes por accidentes de tránsito (AT de residentes en el municipio de Lanús (Provincia de Buenos Aires, Argentina entre los años 1998 y 2004. Para ello se realizó un estudio epidemiológico descriptivo, utilizando datos oficiales de mortalidad de Argentina. Se estudiaron las muertes por AT codificadas por la CIE-10, según residencia y ocurrencia. Se analizaron variables sociodemográficas y económicas mediante análisis uni y bivariados, cálculo de la mortalidad proporcional (MP, razón de mortalidad proporcional (RMP y georreferenciamiento por lugar de residencia y de ocurrencia. Lanús presenta un perfil de mortalidad por AT similar al de los países desarrollados. La combinación de técnicas se presenta como una alternativa interesante para trabajar con datos secundarios, en áreas pequeñas y con pequeños números. Esta investigación proporciona contribuciones para intervenir sobre los problemas relacionados con los AT en el nivel individual y local. Se destaca la necesidad de estudios transdisciplinarios que aborden el problema desde otros enfoques metodológicos.

  19. OCTAVIO PAZ Y EL ACCIDENTE COMO IMAGEN DEL MUNDO Octavio Paz and the accident as world’s image

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    Eduardo Aguayo Rodríguez

    2011-12-01

    Full Text Available Examen del significado de la noción de accidente a partir de una perspectiva amplia que permita integrar antecedentes filológicos, filosóficos e históricos fundamentales. Se analiza la significación del accidente en tanto que imagen de mundo en las sociedades contemporáneas, a partir de una serie de reflexiones teóricas desarrolladas por Octavio Paz durante la década del 60 y, finalmente, se plantean algunas claves que pueden vincular la noción de accidente con la narrativa hispanoamericana del siglo XX.The article deals with the notion of accident from a wide point of view integrating philological, philosophical and historical data. The meaning of accident is analyzed according to the image of the world in the post-industrialized societies, from a set of theorical reflexions developed by Octavio Paz during the 60’s; finally, there is a brief discussion about the possible connections between the notion of accident and the hispanic literacy production in the 20th century, specifically in the field of narrative.

  20. ESTADO ACTUAL DE LA PREVENCIÓN DE LOS ACCIDENTES DE MONTAÑA EN ARAGÓN

    Directory of Open Access Journals (Sweden)

    Ma. Antonia Nerín

    2005-01-01

    - Establecer las necesidades de los colectivos implicados (usuarios, profesionales e nstituciones para reducir la incidencia y severidad de los accidentes de montaña. Para ello, hemos utilizado los resultados de las campañas institucionales Montañas para Vivirlas Seguro de los años 2000, 2001 y 2002, se han analizado las ocupaciones relacionadas con las actividades deportivas en la montaña y hemos consultado directamente con las instituciones implicadas. El nivel de formación e información del usuario de la montaña en Aragón no es el adecuado para el riesgo potencial de las actividades de montaña; mientras que se evidencia la necesidad de reglar algunas profesiones de la montaña. El rescate en montaña es efectivo, eficaz y eficiente; la medicalización es efectiva, eficaz y no eficiente (atendiendo a los criterios de necesidad, oferta y demanda y la prevención -a pesar de los esfuerzos- es no eficaz, no eficiente y no efectiva. Por todo ello, es urgente la creaciÛn de un servicio de vigilancia de los accidentes de montaña, así como un centro que coordine las propuestas y actuaciones orientadas a prevenir los acci-dentes de montaña.

  1. Research progress on children accidental injury%儿童意外伤害的研究进展

    Institute of Scientific and Technical Information of China (English)

    李丽; Patricia Ryan-Krause; 李映兰

    2012-01-01

    从流行病学分布、影响因素以及干预措施等方面综合分析国内外对儿童意外伤害的研究现状,发现相对于流行病学研究而言,中低收入国家对儿童意外伤害问题的研究广度及干预项目的有效性研究均较缺乏,未开展意外伤害发生的心理及行为机制研究.%From the epidemiological distribution,influencing factors and interventions it analyzed the research status of children accidental injury in a-broad and at home comprehensively, and found out compared with the epidemiological studies,the research breadth and effective researches of intervention projects on children accidental injury in low - and middle - income countries were lack,and not to carry out a study on the psychological and behavioral mechanisms of accidental injury.

  2. A comparison study on mental health status between suicide survivors and survivors of accidental deaths in rural China.

    Science.gov (United States)

    Xu, G; Li, N

    2014-12-01

    Suicide has become a major public health problem worldwide. For every suicide there are six suicide survivors, a term referring to family members or friends of a person who has died by suicide. Within the literature there has been ongoing debate regarding the bereavement process and if it differs in survivors of suicide as opposed to survivors of those who have died from accidental death. There are scarcely any published reports on comparison between these two groups of survivors in China. In this study, we aimed to explore the difference of mental health status between suicide survivors and survivors of accidental deaths in China. We used a cross-sectional study design to collect data of survivors. Consecutive sampling was used and 92 suicide survivors and 64 survivors of accidental deaths were interviewed. The Symptom Checklist-90-Revised was used to assess the survivors' mental health status. After controlling for demographic variables and time interval between death and interview, no significant differences were found on mental health status between these two groups of survivors. Several explanations might account for the lack of differences. Further studies employing qualitative measures and suicide-specific instruments are needed to explore the bereavement of Chinese suicide survivors.

  3. EXPOSE-R2, the 3rd successful EXPOSE mission – a mission and mission ground reference overview

    OpenAIRE

    2016-01-01

    For nearly 2 years the 3rd ESA EXPOSE mission, the 2nd on the Russian Zvezda module of the ISS, exposed a variety of astrobiological samples to space and simulated Mars environmental conditions. Various chemical compounds and organisms like bacteria, archaea, fungi, plant seeds, lychens, mosses and animal eggs and larvae from the international experiments BIOMEX, BOSS, P.S.S. and the IBMP-experiment were exposed to space vacuums dryness, extraterrestrial short wavelength UV, radiation and tem...

  4. Cochlear condition and olivocochlear system of gas station attendants exposed to organic solvents

    Directory of Open Access Journals (Sweden)

    Tochetto, Tania Maria

    2012-01-01

    Full Text Available Introduction: Organic solvents have been increasingly studied due to its ototoxic action. Objective: Evaluate the conditions of outer hair cells and olivocochlear system in individuals exposed to organic solvents. Method: This is a prospective study. 78 gas station attendants exposed to organic solvents had been evaluated from three gas stations from Santa Maria city, Rio Grande do Sul (RS. After applying the inclusion criteria, the sample was constituted by 24 individuals. The procedures used on the evaluation were audiological anamnesis, Transient otoacoustic emissions (TEOAES and research for the suppressive effect of TEOAES. A group control (GC compounded by 23 individuals was compared to individuals exposed and non-exposed individuals. The data collection has been done in the room of Speech Therapy of Workers Health Reference Center of Santa Maria. Results: The TEOAES presence was major in the left ear in both groups; the average relation of TEOAES signal/noise in both ears was greater in GE; the TEOAES suppressive effect in the right ear was higher in the individual of GE (62,5% and in the left ear was superior in GC (86,96%, with statistically significant difference. The median sign/noise ratio of TEOAES, according to the frequency range, it was higher in GC in three frequencies ranges in the right ear and one in the left ear. Conclusion: It was not found signs of alteration on the outer hair cells neither on the olivocochlear medial system in the individuals exposed to organic solvents.

  5. Antarctic skuas recognize individual humans.

    Science.gov (United States)

    Lee, Won Young; Han, Yeong-Deok; Lee, Sang-Im; Jablonski, Piotr G; Jung, Jin-Woo; Kim, Jeong-Hoon

    2016-07-01

    Recent findings report that wild animals can recognize individual humans. To explain how the animals distinguish humans, two hypotheses are proposed. The high cognitive abilities hypothesis implies that pre-existing high intelligence enabled animals to acquire such abilities. The pre-exposure to stimuli hypothesis suggests that frequent encounters with humans promote the acquisition of discriminatory abilities in these species. Here, we examine individual human recognition abilities in a wild Antarctic species, the brown skua (Stercorarius antarcticus), which lives away from typical human settlements and was only recently exposed to humans due to activities at Antarctic stations. We found that, as nest visits were repeated, the skua parents responded at further distances and were more likely to attack the nest intruder. Also, we demonstrated that seven out of seven breeding pairs of skuas selectively responded to a human nest intruder with aggression and ignored a neutral human who had not previously approached the nest. The results indicate that Antarctic skuas, a species that typically inhabited in human-free areas, are able to recognize individual humans who disturbed their nests. Our findings generally support the high cognitive abilities hypothesis, but this ability can be acquired during a relatively short period in the life of an individual as a result of interactions between individual birds and humans.

  6. The 5th National Audit Project (NAP5) on accidental awareness during general anaesthesia: summary of main findings and risk factors.

    Science.gov (United States)

    Pandit, J J; Andrade, J; Bogod, D G; Hitchman, J M; Jonker, W R; Lucas, N; Mackay, J H; Nimmo, A F; O'Connor, K; O'Sullivan, E P; Paul, R G; Palmer, J H MacG; Plaat, F; Radcliffe, J J; Sury, M R J; Torevell, H E; Wang, M; Hainsworth, J; Cook, T M

    2014-10-01

    We present the main findings of the 5th National Audit Project on accidental awareness during general anaesthesia. Incidences were estimated using reports of accidental awareness as the numerator, and a parallel national anaesthetic activity survey to provide denominator data. The incidence of certain/probable and possible accidental awareness cases was ~1:19 600 anaesthetics (95% CI 1:16 700-23 450). However, there was considerable variation across subtypes of techniques or subspecialties. The incidence with neuromuscular blockade was ~1:8200 (1:7030-9700), and without it was ~1:135 900 (1:78 600-299 000). The cases of accidental awareness during general anaesthesia reported to 5th National Audit Project were overwhelmingly cases of unintended awareness during neuromuscular blockade. The incidence of accidental awareness during caesarean section was ~1:670 (1:380-1300). Two thirds (82, 66%) of cases of accidental awareness experiences arose in the dynamic phases of anaesthesia, namely induction of and emergence from anaesthesia. During induction of anaesthesia, contributory factors included: use of thiopental; rapid sequence induction; obesity; difficult airway management; neuromuscular blockade; and interruptions of anaesthetic delivery during movement from anaesthetic room to theatre. During emergence from anaesthesia, residual paralysis was perceived by patients as accidental awareness, and commonly related to a failure to ensure full return of motor capacity. One third (43, 33%) of accidental awareness events arose during the maintenance phase of anaesthesia, most due to problems at induction or towards the end of anaesthesia. Factors increasing the risk of accidental awareness included: female sex; age (younger adults, but not children); obesity; anaesthetist seniority (junior trainees); previous awareness; out-of-hours operating; emergencies; type of surgery (obstetric, cardiac, thoracic); and use of neuromuscular blockade. The following factors were

  7. Accidentes de trabajo en el Hospital Clínico de la Universidad de Chile durante el año 2007

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    Carlos Valdés

    2011-01-01

    Full Text Available Objetivo: Conocer el número de los accidentes laborales en el Hospital Clínico de la Universidad de Chile (HCUCH el año 2007 y su caracterización de acuerdo a variables como: sexo, edad, tipo de lesión, día de la semana, mes del año, cargo desempeñado y días perdidos. Diseño: Estudio descriptivo, transversal, retrospectivo y observacional. Lugar: Hospital Clínico de la Universidad de Chile (HCUCH. Participantes: Accidentes laborales reportados entre el 1 de Enero y el 31 de Diciembre del 2007. Intervención: Se utilizó la base de datos del Registro de Notificación de Accidentes Laborales, proporcionada por el Departamento de Prevención de Riesgos del HCUCH Principales medidas de Resultados: Porcentajes y Medidas de Tendencia Central, tabuladas en una base de datos con ayuda del programa Microsoft Excel 2003 para Windows ®. Resultados: Se observan 104 accidentes laborales, con un mayor número de eventos en el personal femenino (69,2%, en el rango etareo de 30-39 años (34,3%, el tipo de lesión más frecuente fueron las contusiones policontusiones (39,4%, el grupo más accidentado fue los auxiliares y técnicos (71.1%. El estudio por días de la semana revela que hay más accidentes los días miércoles y jueves (43,27% y los meses del año con más accidentes fueron enero, agosto y diciembre. La mayor cantidad de accidentes laborales comprometen entre 1 a 5 días perdidos. Conclusiones: Durante el año 2007, se pesquisó 104 accidentes laborales, lo que significó 804 días de ausentismo. Este estudio muestra que el sexo femenino, tener entre 30-39 años y ejercer como auxiliar o técnico fueron factores de asociados al incremento de los accidentes laborales. Palabras clave: Accidentes de trabajo, ausentismo, notificación de accidentes de trabajo.

  8. ACCIDENTES CON EXPOSICIÓN A MATERIAL BIOLÓGICO CONTAMINADO POR VIH EN TRABAJADORES DE UN HOSPITAL DE TERCER NIVEL DE MADRID (1986-2001

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    Aurelia García de Codes Ilario

    2004-01-01

    Full Text Available Fundamento: La contaminación por el virus de la inmunodeficiencia humana (VIH es un riesgo ocupacional para los profesionales sanitarios accidentados contaminados con sangre positiva al VIH. El objetivo de nuestro estudio es describir las características de los accidentes registrados durante dieciséis años en un hospital general con sangre o fluidos biológicos procedentes de pacientes VIH positivos, determinar las tasas de exposición accidental en las diferentes categorías profesionales y comprobar el seguimiento realizado por los trabajadores del protocolo de accidentes establecido. Métodos: Estudio descriptivo en un hospital general de Madrid durante el período 1986 a 2001, de los accidentes con presencia de material biológico procedente de personas con serología VIH positiva. Se han estudiado variables del profesional accidentado relacionadas con persona, lugar y tiempo, además de las serologías al inicio y durante el seguimiento protocolizado. Resultados: Durante el período de estudio se declararon 550 accidentes con fuente VIH positiva. La media fue de 34,4 de accidentes por año. La tasa de exposición fue de 7,5 por cada 1.000 trabajadores- año. El colectivo profesional con mayor frecuencia de accidentes fue el personal de enfermería (54,4%. Las lesiones percutáneas fueron las más frecuentes (80,2%. La tasa media de exposición ha sido de 2,6 por cada 100 camas-año. Las zonas anatómicas más afectadas fueron los dedos de la mano (75,6%. El 53,6% de los accidentados finalizó el seguimiento serológico, sin registrarse ninguna seroconversión. Conclusiones: Durante los dieciséis años de estudio, la incidencia anual de accidentes con fuente VIH positiva fue en aumento desde los 27 accidentes declarados en 1986 hasta los 60 accidentes en 1990, con una tendencia descendente desde ese momento hasta contabilizarse 12 accidentes en el año 2001.

  9. Prescripción facilitada de drogas antihipertensivas y disminución de la muerte prematura por accidente cerebrovascular

    Directory of Open Access Journals (Sweden)

    Javier Mariani

    2016-04-01

    Full Text Available Introducción: Desde 2003, el programa Remediar (+Redes distribuye gratuitamente medicación antihipertensiva. Durante este período, la mortalidad por accidente cerebrovascular disminuyó, aunque con inequidades entre grupos socioeconómicos. Objetivos: Evaluar la asociación entre la mortalidad por accidente cerebrovascular y la provisión de fármacos antihipertensivos. Estudiar la posible interacción entre los efectos de los antihipertensivos sobre la mortalidad y el nivel socioeconómico. Material y métodos: Se realizó un estudio ecológico para datos de panel. La mortalidad se expresa como tasas estandarizadas.Los fármacos antihipertensivos están ajustados a la población entre la que se distribuyeron y se expresan en cuartiles dedispensación. El nivel socioeconómico se midió por las necesidades básicas insatisfechas. Resultados: Desde el inicio del programa en 2003, la distribución de antihipertensivos aumentó significativamente, sobre todo en los grupos menos afluentes (p < 0,001. No hubo una asociación estadísticamente significativa entre la tasa de dispensaciónde antihipertensivos y la mortalidad por accidente cerebrovascular globalmente. Sin embargo, en los análisis de interacción se observó que en los quintiles 3 a 5 de necesidades básicas insatisfechas (menos afluentes, los cuartiles en los que se distribuyeron más antihipertensivos tuvieron significativamente menor mortalidad por accidente cerebrovascular (p = 0,004,p = 0,015 y p = 0,017, para los quintiles 3 a 5 de nivel socioeconómico. Conclusiones: Los resultados del presente análisis sugieren la ausencia de efectos globales de la provisión de antihipertensivossobre la mortalidad por accidente cerebrovascular. Sin embargo, los datos muestran que, entre los grupos más desfavorecidos,la distribución de antihipertensivos estuvo asociada con una reducción de la mortalidad por esta causa.

  10. Terapéuticas intervencionistas para el accidente cerebrovascular isquémico

    Directory of Open Access Journals (Sweden)

    Alejandra T. Rabadán

    2010-10-01

    Full Text Available En los últimos 20 años se han desarrollado nuevas opciones para el tratamiento y para la prevención del accidente cerebrovascular (ACV isquémico, muchas de ellas de carácter intervencionista, tales como la endarterectomía carotídea y la trombolisis intravenosa con activador tisular del plasminógeno. La evidencia científica ha llevado a su difusión y utilización en países desarrollados mientras que en naciones emergentes se observa un retraso en su adopción. Otras modalidades terapéuticas que parecen ser muy promisorias, aunque sin tanta evidencia científica que las avale, requieren la realización y conclusión de estudios randomizados. Dentro de la evolución del ACV isquémico existe una situación particular como es el infarto cerebral "maligno". Constituye un evento devastador, que se presenta en aproximadamente el 10 al 15% de los ACV carotídeos o silvianos, y está asociado con elevada morbimortalidad. Con la información disponible actualmente, es posible recomendar la craniectomía descompresiva (CD como un método efectivo y seguro para disminuir rápidamente la presión intracraneal y lograr un pronóstico favorable sobre una base racional. Aunque no hay estudios randomizados y controlados en la literatura, existe suficiente evidencia para recomendar la CD en casos especiales.

  11. Fouling Communities of Two Accidental Artificial Reefs (Modern Shipwrecks in Cyprus (Levantine Sea

    Directory of Open Access Journals (Sweden)

    Carlos Jimenez

    2016-12-01

    Full Text Available Artificial reefs are considered one of the alternative methods in fisheries management, used in order to enhance stocks and marine biodiversity in general. A number of biotic and abiotic parameters influence the fouling communities’ formation on artificial reefs through complex interactions. In order to understand how epibiotic or fouling communities progress through time, it is important to study these communities in mature artificial reefs, especially those that have been around for many decades, or in some cases, millennia. This study was conducted on the coral and other fouling organisms of two accidental artificial reefs (40 to 70 year-old shipwrecks in Cyprus (Levantine Sea. The thermal and nutrient annual regime of the study sites were characterized by processing satellite data. The results indicate that the wrecks are normally under warm and oligotrophic conditions. Percentage coverage of corals and other organisms on the wrecks was calculated (image-analysis software on photos taken in 2010 (two wrecks and again in 2016 (one wreck of the fouling communities. Sponges were the organisms with the highest percent cover (~27% at the two wrecks. Four scleractinian coral species were found (7%–19% total coral cover. The oldest wreck, which has well-developed coral communities, was revisited during fieldwork in a near-by area in 2016. Only two major benthic categories (dead coral and macro algae changed significantly between sampling periods. Given the actual policies to sink wrecks to create artificial reefs and the diverse environmental conditions in different areas that will inevitably influence fouling, it is important to carry out studies relating to mature artificial reefs/wrecks in order to be able to assess the ecological effectiveness of longstanding artificial reefs.

  12. Assessment of methodologies for analysis of the dungeness B accidental aircraft crash risk.

    Energy Technology Data Exchange (ETDEWEB)

    LaChance, Jeffrey L.; Hansen, Clifford W.

    2010-09-01

    The Health and Safety Executive (HSE) has requested Sandia National Laboratories (SNL) to review the aircraft crash methodology for nuclear facilities that are being used in the United Kingdom (UK). The scope of the work included a review of one method utilized in the UK for assessing the potential for accidental airplane crashes into nuclear facilities (Task 1) and a comparison of the UK methodology against similar International Atomic Energy Agency (IAEA), United States (US) Department of Energy (DOE), and the US Nuclear Regulatory Commission (NRC) methods (Task 2). Based on the conclusions from Tasks 1 and 2, an additional Task 3 would provide an assessment of a site-specific crash frequency for the Dungeness B facility using one of the other methodologies. This report documents the results of Task 2. The comparison of the different methods was performed for the three primary contributors to aircraft crash risk at the Dungeness B site: airfield related crashes, crashes below airways, and background crashes. The methods and data specified in each methodology were compared for each of these risk contributors, differences in the methodologies were identified, and the importance of these differences was qualitatively and quantitatively assessed. The bases for each of the methods and the data used were considered in this assessment process. A comparison of the treatment of the consequences of the aircraft crashes was not included in this assessment because the frequency of crashes into critical structures is currently low based on the existing Dungeness B assessment. Although the comparison found substantial differences between the UK and the three alternative methodologies (IAEA, NRC, and DOE) this assessment concludes that use of any of these alternative methodologies would not change the conclusions reached for the Dungeness B site. Performance of Task 3 is thus not recommended.

  13. [Thermolabile drugs stability faced with an accidental interruption in the cold chain].

    Science.gov (United States)

    Ricote-Lobera, I; Ortiz-Martín, B; Fraile-Gil, S; Santos-Mena, B; Hidalgo-Correas, F J; García-Díaz, B

    2014-05-01

    Objetivo: Elaborar una guía actualizada sobre la estabilidad delos medicamentos termolábiles incluidos en la Guía Farmacoterapéuticaque, según ficha técnica, deben conservarse bajorefrigeración o congelación, expuestos accidentalmente a temperaturasde conservación fuera del rango recomendado por elfabricante.Métodos: Se revisó la información sobre las temperaturas deconservación recomendadas en ficha técnica y los datos deestabilidad disponibles a distintas temperaturas de los medicamentostermolábiles incluidos en la Guía Farmacoterapéuticade un hospital de 400 camas que, según el fabricante, debenconservarse bajo refrigeración o congelación. Se excluyeron losmedicamentos incluidos en ensayos clínicos. Los datos de estabilidadse obtuvieron a partir de la ficha técnica, la informacióncontenida en las dos últimas guías de conservación de medicamentostermolábiles publicadas en España y a través de las consultasrealizadas a los laboratorios (vía telefónica o por e-mail).Resultados: Se confeccionó una tabla con las temperaturas deconservación recomendadas en ficha técnica y los datos deestabilidad disponibles actualmente a distintas temperaturas de209 presentaciones de distintas especialidades farmacéuticas.Se solicitaron datos de estabilidad actualizados de 172 de ellasa los laboratorios.Conclusiones: La guía elaborada constituye una herramientaque facilita la toma de decisiones del farmacéutico ante unarotura accidental de la cadena de frío, cuando sea necesarioconocer si el fármaco puede ser utilizado y no sea posible contactarcon el laboratorio fabricante.

  14. Genotypic and phenotypic modifications of Neisseria meningitidis after an accidental human passage.

    Directory of Open Access Journals (Sweden)

    Hélène Omer

    Full Text Available A scientist in our laboratory was accidentally infected while working with Z5463, a Neisseria meningitidis serogroup A strain. She developed severe symptoms (fever, meningism, purpuric lesions that fortunately evolved with antibiotic treatment to complete recovery. Pulse-field gel electrophoresis confirmed that the isolate obtained from the blood culture (Z5463BC was identical to Z5463, more precisely to a fourth subculture of this strain used the week before the contamination (Z5463PI. In order to get some insights into genomic modifications that can occur in vivo, we sequenced these three isolates. All the strains contained a mutated mutS allele and therefore displayed an hypermutator phenotype, consistent with the high number of mutations (SNP, Single Nucleotide Polymorphism detected in the three strains. By comparing the number of SNP in all three isolates and knowing the number of passages between Z5463 and Z5463PI, we concluded that around 25 bacterial divisions occurred in the human body. As expected, the in vivo passage is responsible for several modifications of phase variable genes. This genomic study has been completed by transcriptomic and phenotypic studies, showing that the blood strain used a different haemoglobin-linked iron receptor (HpuA/B than the parental strains (HmbR. Different pilin variants were found after the in vivo passage, which expressed different properties of adhesion. Furthermore the deletion of one gene involved in LOS biosynthesis (lgtB results in Z5463BC expressing a different LOS than the L9 immunotype of Z2491. The in vivo passage, despite the small numbers of divisions, permits the selection of numerous genomic modifications that may account for the high capacity of the strain to disseminate.

  15. Actividades intersectoriales en la prevención de accidentes de tráfico

    Directory of Open Access Journals (Sweden)

    Peiró R.

    2003-01-01

    Full Text Available Se describen las líneas de trabajo priorizadas y algunos resultados obtenidos en la implantación del programa de prevención y reducción de lesiones por accidentes de tráfico en un área de salud. A partir de 1999 el Centro de Salud Pública priorizó la identificación y búsqueda de aliados en otros sectores (Asociación de policías locales y educación, la construcción de la capacidad de trabajo conjunta y la formación de un grupo intersectorial. Se llevaron a cabo actividades docentes y jornadas. Se formó una red de personas en 17 de un total de 39 ayuntamientos que participan con actividades en el grupo intersectorial. Un total de 10 de estos ayuntamientos participaron con actividades educativas y siete, además, exigieron al cumplimiento de la legislación. El grupo intersectorial potenció la visibilidad de sus actividades a través de los medios de comunicación local. Estas actividades no están dirigidas a reducir las lesiones por tráfico, sino a crear un marco de trabajo para la movilización de los sectores implicados. Se pretende potenciar más el compromiso entre los niveles políticos, técnicos y civiles incidiendo en valores sociales de respeto para una vida más saludable.

  16. Aspectos psicosociales y accidentes en el transporte terrestre Psychosocial aspects and accidents in land transport

    Directory of Open Access Journals (Sweden)

    Nelson Morales-Soto

    2010-06-01

    Full Text Available Los accidentes de tránsito son un problema de salud pública en el Perú, que entre 1998 y 2008 causaron 35 596 muertes, Lima es la región más afectada con 61,7% de los siniestros, su costo anual alcanzó los mil millones de dólares, equivalente a un tercio de la inversión en salud. Los estudios disponibles enfatizan en los protagonistas -conductores, peatones- o en equipos y vías; se han modificado normas e implementado planes de contención de la siniestralidad pero su incidencia persiste. Se plantea la posibilidad de explorar factores conductuales y sociales que podrían tener importancia en la génesis del problema revisando los relacionados con el desorden imperante en el transporte, los comportamientos de conductores y peatones y la permisividad de la sociedad en general, particularmente de la autoridad. Se propone la investigación e intervención multidisciplinaria e intersectorial.Road traffic accidents are a public health problem in Peru, having caused 35 596 deaths in Peru between 1998 and 2008. Lima is the most affected region, presenting 61.7% of the accidents, the annual cost reached one thousand million dollars, equivalent to a third part of the investment in health. Available studies give emphasis to the protagonists -the drivers, the pedestrians- or to equipment and roads; the laws have been modified and containment plans for accidents have been implemented, but the incidence remains the same. We raise the possibility of exploring behavioral and social factors that could be relevant in the genesis of the problem, revising those related to current disorder in transport, the behaviors of drivers and pedestrians and the permissiveness of society in general particularly of the authority. We propose research and a multidisciplinary and intersectoral intervention.

  17. The quest for an intermediate-scale accidental axion and further ALPs

    Energy Technology Data Exchange (ETDEWEB)

    Dias, A.G.; Nishi, C.C. [Univ. Federal do ABC - UFABC, Sao Paulo (Brazil); Machado, A.C.B. [Teorica-Univ. Estadual Paulista, Sao Paulo (Brazil). Instituto de Fisica; Ringwald, A. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Vaudrevange, P. [Technische Univ. Muenchen, Garching (Germany). Excellence Cluster Universe

    2014-03-15

    The recent detection of the cosmic microwave background polarimeter experiment BICEP2 of tensor fluctuations in the B-mode power spectrum basically excludes all plausible axion models where its decay constant is above 10{sup 13} GeV. Moreover, there are strong theoretical, astrophysical, and cosmological motivations for models involving, in addition to the axion, also axion-like particles (ALPs), with decay constants in the intermediate scale range, between 10{sup 9} GeV and 10{sup 13} GeV. Here, we present a general analysis of models with an axion and further ALPs and derive bounds on the relative size of the axion and ALP photon (and electron) coupling. We discuss what we can learn from measurements of the axion and ALP photon couplings about the fundamental parameters of the underlying ultraviolet completion of the theory. For the latter we consider extensions of the Standard Model in which the axion and the ALP(s) appear as pseudo Nambu-Goldstone bosons from the breaking of global chiral U(1) (Peccei-Quinn (PQ)) symmetries, occuring accidentally as low energy remnants from exact discrete symmetries. In such models, the axion and the further ALP are protected from disastrous explicit symmetry breaking effects due to Planck-scale suppressed operators. The scenarios considered exploit heavy right handed neutrinos getting their mass via PQ symmetry breaking and thus explain the small mass of the active neutrinos via a seesaw relation between the electroweak and an intermediate PQ symmetry breaking scale. We show some models that can accommodate simultaneously an axion dark matter candidate, an ALP explaining the anomalous transparency of the universe for γ-rays, and an ALP explaining the recently reported 3.55 keV gamma line from galaxies and clusters of galaxies, if the respective decay constants are of intermediate scale.

  18. CXCL12 expression in hematopoietic tissues of mice exposed to sublethal dose of ionizing radiation in the presence od iNOS inhibitor

    Energy Technology Data Exchange (ETDEWEB)

    Perez Vieira, Daniel [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil). Lab. de Biologia Molecular; Hermida, Felipe Pessoa de Melo; Andrade Junior, Heitor Franco de [Instituto de Medicina Tropical de Sao Paulo, SP (Brazil). Lab. de Protozoologia

    2005-07-01

    their use associated to the CXCL12 chemokine to enhance the post-transplantation grafting of hematopoietic tissue and/or treatment of accidentally exposed individuals to sublethal doses of ionizing radiation. (author)

  19. Thinking the individual as form of individuation

    Directory of Open Access Journals (Sweden)

    Samuel Mateus

    2011-12-01

    Full Text Available In this paper we will ponder the problem of the individualism through the individuation, pointing out the implications on the idea of “individual”. It attempts to find a theoretical way that allows a broader understanding of its role in human societies It will be suggested that the emphasis placed by modernity in the individual can be evaluated, not as a solipsist individualism, but as a figurational form specific of social contexts characterized by a wide objectivation of the social tissue. That means that beside individualism we can think individualizations through the seminal setting of individuation. This hypothesis is already insinuated in the German sociological thought, in particular, in the sociology of the social forms of Georg Simmel and in the process sociology of Norbert Elias.

  20. Effect of low-dose radiation on frequencies of chromosome aberrations and micronucleus-containing cells of occupationally exposed individuals: a Meta analysis%低剂量电离辐射对职业暴露人群染色体畸变率和微核细胞率影响的Meta分析

    Institute of Scientific and Technical Information of China (English)

    姜晶; 高露; 黄波; 周平坤; 让蔚清

    2014-01-01

    .Conclusions The frequencies of chromosome aberrations and micronucleus cell of peripheral lymphocytes are significantly high in radiation workers who were occupationally exposed to low-dose ionizing radiation.It should be noted that the radiation protection of radiological workers be enhanced.

  1. Genetic damage in subjects exposed to radiofrequency radiation.

    Science.gov (United States)

    Verschaeve, Luc

    2009-01-01

    Despite many research efforts and public debate there is still great concern about the possible adverse effects of radiofrequency (RF) radiation on human health. This is especially due to the enormous increase of wireless mobile telephones and other telecommunication devices throughout the world. The possible genetic effects of mobile phone radiation and other sources of radiofrequencies constitute one of the major points of concern. In the past several review papers were published on laboratory investigations that were devoted to in vitro and in vivo animal (cyto)genetic studies. However, it may be assumed that some of the most important observations are those obtained from studies with individuals that were exposed to relatively high levels of radiofrequency radiation, either as a result of their occupational activity or as frequent users of radiofrequency emitting tools. In this paper the cytogenetic biomonitoring studies of RF-exposed humans are reviewed. A majority of these studies do show that RF-exposed individuals have increased frequencies of genetic damage (e.g., chromosomal aberrations) in their lymphocytes or exfoliated buccal cells. However, most of the studies, if not all, have a number of shortcomings that actually prevents any firm conclusion. Radiation dosimetry was lacking in all papers, but some of the investigations were flawed by much more severe imperfections. Large well-coordinated multidisciplinary investigations are needed in order to reach any robust conclusion.

  2. Investigação de acidentes biológicos entre profissionais de saúde Investigación de accidentes biológicos entre los trabajadores de la salud Investigation of biological accidents among health care workers

    Directory of Open Access Journals (Sweden)

    Juliana Azevedo da Silva

    2009-09-01

    Full Text Available Os objetivos deste trabalho foram identificar a principal categoria profissional exposta a risco biológico e os principais tipos de acidentes ocorridos entre trabalhadores da área de saúde, em Campos dos Goytacazes, RJ. A partir da análise das fichas de notificação de acidentes biológicos dos 183 profissionais acidentados entre janeiro de 2005 e setembro de 2005, observamos que a categoria profissional mais exposta foi a dos auxiliares/técnicos de enfermagem (54,1%, seguida pela dos acadêmicos de medicina e odontologia (10,4%. A ocorrência de acidentes com materiais perfurocortantes foi relacionada à manipulação frequente desses objetos e ao comportamento dos profissionais que utilizam práticas que oferecem riscos de acidentes com agulhas, tais como o descarte inadequado de objetos perfurocortantes.El objetivo de este estudio fue identificar las principales categorías profesional expuestas a riesgos biológicos y el principal tipo de accidentes producidos entre los profesionales del área de la salud en Campos dos Goytacazes, RJ. Del análisis de 183 archivos de los trabajadores que sufren accidentes con material biológico, de enero a septiembre de 2005, se observó que la categoría profesional más expuesta a sufrir accidentes fue el de los auxiliares de enfermería (54,1%, seguido por los estudiantes de odontología y medicina (10,4%. La de accidentes se relacionó con la manipulación frecuente de agujas, y con el comportamiento de los trabajadores, que mantienen prácticas que ofrecen riesgos, como la eliminación inadecuada de agujas.The aims of this study were to identify the major professional category exposed to biological risk and the principal type of accident occurred among health care workers in Campos dos Goytacazes, RJ. Based on the analysis of 183 records filled out by the workers who suffered biohazardous accidents between January 2005 and September 2005, we found the nursing auxiliaries and technicians as the

  3. Un análisis en los accidentes cerebrovasculares una nueva mirada a los factores de riesgo para la aparición de la enfermedad. Un análisis en los accidentes cerebrovasculares

    OpenAIRE

    2013-01-01

    ResumenLa presencia o no de factores psicológicos de riesgo para la aparición de distintas enfermedades continúa siendo un tema controvertido en las ciencias médicas y psicológicas, quizás por las dificultades que se presentan en el momento de su evaluación. No obstante, ya se han realizado primeras miradas en este sentido, presentando la siguiente investigación en personas con accidente cerebrovascular, como un análisis preliminar experimental; que más que brindar datos definitorios, permita...

  4. Long-term environmental fate of perfluorinated compounds after accidental release at Toronto airport.

    Science.gov (United States)

    Awad, Emily; Zhang, Xianming; Bhavsar, Satyendra P; Petro, Steve; Crozier, Patrick W; Reiner, Eric J; Fletcher, Rachael; Tittlemier, Sheryl A; Braekevelt, Eric

    2011-10-01

    Perfluorooctane sulfonate (PFOS; a perfluorinated compound or PFC), its salts, and perfluorooctane sulfonyl fluoride have recently been listed in Annex B of the Stockholm Convention due to their widespread presence, persistence, and toxicity. Because of the persistent nature of PFCs, it is generally presumed that the impact of direct discharges of these chemicals on a receiving environment would be long-lasting. However, long-term environmental fate studies based on field measurements are rare. We examined spatial and long-term (9 year) temporal trends of PFCs in water, sediment, fish, and fish liver collected in 2003, 2006, and 2009 from 10 locations spanning ∼20 km in Etobicoke and Spring Creeks, where an accidental release of fire fighting foam containing PFOS from nearby Toronto International Airport occurred in 2000. Even a decade after the spill, sediment PFOS concentrations are still elevated in Spring Creek Pond which received the foam discharge; however, the major impact is relatively localized likely due to the stormwater management nature of the pond and the diluting effect of Etobicoke Creek. Fish and fish liver PFOS concentrations at a Spring Creek location downstream of Spring Creek Pond declined by about 70 and 85%, respectively, between 2003 and 2009. PFOS in water at locations further downstream in Etobicoke Creek have declined by >99.99% since the spill; however, the 2009 water and fish levels were ∼2-10 times higher than upstream locations likely due to the long-term impact of the spill as well as urbanization. The decrease in the upstream PFOS concentrations likely reflects the reduction of PFOS sources due to phased out production by 3M and regulations on the use of PFOS in fire fighting foams. Field-based sediment/water distribution coefficients (K(D)) and bioaccumulation factors (BAF) were calculated from environmental measurements. Log K(D) values were 0.54-1.65 for perfluoroalkyl sulfonates (PFASs) and 1.00-1.85 for

  5. Estimation of vulnerable zones due to accidental release of toxic materials resulting in dense gas clouds.

    Science.gov (United States)

    Singh, M P; Mohan, M; Panwar, T S; Chopra, H V

    1991-09-01

    Heavy gas dispersion models have been developed at IIT (hereinafter referred as IIT heavy gas models I and II) with a view to estimate vulnerable zones due to accidental (both instantaneous and continuous, respectively) release of dense toxic material in the atmosphere. The results obtained from IIT heavy gas models have been compared with those obtained from the DEGADIS model [Dense Gas Dispersion Model, developed by Havens and Spicer (1985) for the U.S. Coast Guard] as well as with the observed data collected during the Burro Series, Maplin Sands, and Thorney Island field trials. Both of these models include relevant features of dense gas dispersion, viz., gravity slumping, air entrainment, cloud heating, and transition to the passive phase, etc. The DEGADIS model has been considered for comparing the performance of IIT heavy gas models in this study because it incorporates most of the physical processes of dense gas dispersion in an elaborate manner, and has also been satisfactorily tested against field observations. The predictions from IIT heavy gas models indicate a fairly similar trend to the observed values from Thorney Island, Burro Series, and Maplin experiments with a tendency toward overprediction. There is a good agreement between the prediction of IIT Heavy Gas models I and II with those from DEGADIS, except for the simulations of IIT heavy gas model-I pertaining to very large release quantities under highly stable atmospheric conditions. In summary, the performance of IIT heavy gas models have been found to be reasonably good both with respect to the limited field data available and various simulations (selected on the basis of relevant storages in the industries and prevalent meteorological conditions performed with DEGADIS). However, there is a scope of improvement in the IIT heavy gas models (viz., better formulation for entrainment, modification of coefficients, transition criteria, etc.). Further, isotons (nomograms) have been prepared by using

  6. Surgical management of accidentally displaced mandibular third molar into the pterygomandibular space: a case report.

    Science.gov (United States)

    Huang, I-Yueh; Chen, Chao-Ming; Chang, Sung-Wen; Yang, Chia-Fu; Chen, Chung-Ho; Chen, Chun-Min

    2007-07-01

    Surgical removal of the mandibular third molar is a regular surgical procedure in dental clinics, and like all operations, it may have some complications, such as infection, bleeding, nerve injuries, trismus and so on. An accidentally displaced lower third molar is a relatively rare complication, but may cause severe tissue injury and medicolegal problems. As few papers and cases have been published on this topic, we report this case to remind dentists on ways to prevent and manage this complication. The patient, a 28-year-old male, had his right lower mandibular third molar extraction in January 2006. The dentist resected the crown and attempted to remove the root but found that it had suddenly disappeared from the socket. Assuming that the root had been suctioned out he closed the wound. The patient was not followed up regularly because he studied abroad. About 3 months later, the patient felt a foreign body sensation over his right throat, and visited a local hospital in Australia. He was told after a computed tomography (CT) scan that there was a root-like radio-opaque image in the pterygomandibular space. The patient came to our hospital for further examination and management in June 2006. We rechecked with both Panorex and CT and confirmed the location of the displaced root. Surgery for retrieving the displaced root was performed under general anesthesia by conventional method without difficulty, and the wound healed uneventfully except for a temporary numbness of the right tongue. This case reminds us that the best way to prevent a displaced mandibular third molar is to evaluate the condition of the tooth carefully preoperatively, select adequate instruments and technique, and take good care during extraction. If an accident does occur, dentists should decide whether to retrieve it immediately by themselves or refer the case to an oral and maxillofacial surgeon, and should not try to remove the displaced root without proper assurance. Localization with

  7. Probabilistic margin evaluation on accidental transients for the ASTRID reactor project

    Science.gov (United States)

    Marquès, Michel

    2014-06-01

    ASTRID is a technological demonstrator of Sodium cooled Fast Reactor (SFR) under development. The conceptual design studies are being conducted in accordance with the Generation IV reactor objectives, particularly in terms of improving safety. For the hypothetical events, belonging to the accidental category "severe accident prevention situations" having a very low frequency of occurrence, the safety demonstration is no more based on a deterministic demonstration with conservative assumptions on models and parameters but on a "Best-Estimate Plus Uncertainty" (BEPU) approach. This BEPU approach ispresented in this paper for an Unprotected Loss-of-Flow (ULOF) event. The Best-Estimate (BE) analysis of this ULOFt ransient is performed with the CATHARE2 code, which is the French reference system code for SFR applications. The objective of the BEPU analysis is twofold: first evaluate the safety margin to sodium boiling in taking into account the uncertainties on the input parameters of the CATHARE2 code (twenty-two uncertain input parameters have been identified, which can be classified into five groups: reactor power, accident management, pumps characteristics, reactivity coefficients, thermal parameters and head losses); secondly quantify the contribution of each input uncertainty to the overall uncertainty of the safety margins, in order to refocusing R&D efforts on the most influential factors. This paper focuses on the methodological aspects of the evaluation of the safety margin. At least for the preliminary phase of the project (conceptual design), a probabilistic criterion has been fixed in the context of this BEPU analysis; this criterion is the value of the margin to sodium boiling, which has a probability 95% to be exceeded, obtained with a confidence level of 95% (i.e. the M5,95percentile of the margin distribution). This paper presents two methods used to assess this percentile: the Wilks method and the Bootstrap method ; the effectiveness of the two methods

  8. ANALYSIS OF REPORTS ABOUT 384 ELDERLY CASES OF ACCIDENTAL INJURY IN COMMUNITY%384例社区老年人意外伤害报告分析

    Institute of Scientific and Technical Information of China (English)

    薛锦花

    2011-01-01

    [Objective] To understand the characteristics and causes of accidental injury of the elderly in community, in order to provide bases for preventing the occurrence of accidental injuries. [Methods] Retrospectively summarized the reports about 384 elderly cases of accidental injury in community. [Results] Homes and roads were the main sites for injury accidents; falling down and falling in accidental injuries were the main reasons for the elderly; accidental injury easily leaded to fractures of the elderly. [Conclusion] Physical characteristics of the elderly easily lead to accidental injury; improving the environment and facilities, preventing falls and preventing osteoporosis are the focuses in preventing accidental injuries; it should establish and improve accident prevention network.%[目的]了解社区老年人意外伤害的特点与原因,为防范意外伤害的发生提供依据. [方法]回顾性总结某社区卫生服务中心从2007年6月~2009年12月的384例社区老年人意外伤害报告. [结果]家中和公路是老年人发生意外伤害的主要场所;跌倒、坠落是老年人意外伤害的主要原因;老年人意外伤害易导致骨折.[结论]老年人的身体特点易导致意外伤害;改善环境设施、预防跌倒、预防骨质疏松症是防范意外伤害的重点;应建立健全意外伤害防护网络.

  9. Eryptosis in lead-exposed workers

    Energy Technology Data Exchange (ETDEWEB)

    Aguilar-Dorado, Itzel-Citlalli [Biochemistry Department, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico); Hernández, Gerardo [Section of Methodology of Science, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico); Quintanar-Escorza, Martha-Angelica [Faculty of Medicine, UJED, Durango, DGO (Mexico); Maldonado-Vega, María [CIATEC, León, GTO (Mexico); Rosas-Flores, Margarita [Biochemistry Department, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico); Calderón-Salinas, José-Víctor, E-mail: jcalder@cinvestav.mx [Biochemistry Department, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico)

    2014-12-01

    Eryptosis is a physiological phenomenon in which old and damaged erythrocytes are removed from circulation. Erythrocytes incubated with lead have exhibited major eryptosis. In the present work we found evidence of high levels of eryptosis in lead exposed workers possibly via oxidation. Blood samples were taken from 40 male workers exposed to lead (mean blood lead concentration 64.8 μg/dl) and non-exposed workers (4.2 μg/dl). The exposure to lead produced an intoxication characterized by 88.3% less δ-aminolevulinic acid dehydratase (δALAD) activity in lead exposed workers with respect to non-lead exposed workers. An increment of oxidation in lead exposed workers was characterized by 2.4 times higher thiobarbituric acid-reactive substance (TBARS) concentration and 32.8% lower reduced/oxidized glutathione (GSH/GSSG) ratio. Oxidative stress in erythrocytes of lead exposed workers is expressed in 192% higher free calcium concentration [Ca{sup 2+}]{sub i} and 1.6 times higher μ-calpain activity with respect to non-lead exposed workers. The adenosine triphosphate (ATP) concentration was not significantly different between the two worker groups. No externalization of phosphatidylserine (PS) was found in non-lead exposed workers (< 0.1%), but lead exposed workers showed 2.82% externalization. Lead intoxication induces eryptosis possibly through a molecular pathway that includes oxidation, depletion of reduced glutathione (GSH), increment of [Ca{sup 2+}], μ-calpain activation and externalization of PS in erythrocytes. Identifying molecular signals that induce eryptosis in lead intoxication is necessary to understand its physiopathology and chronic complications. - Graphical abstract: Fig. 1. (A) Blood lead concentration (PbB) and (B) phosphatidylserine externalization on erythrocyte membranes of non-lead exposed (□) and lead exposed workers (■). Values are mean ± SD. *Significantly different (P < 0.001). - Highlights: • Erythrocytes of lead exposed workers

  10. Prediction of ground vibration due to the collapse of a 235 m high cooling tower under accidental loads

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Feng; Li, Yi [Department of Building Engineering, Tongji University, No. 1239 Siping Road, Shanghai 200092 (China); Gu, Xianglin, E-mail: gxl@tongji.edu.cn [Department of Building Engineering, Tongji University, No. 1239 Siping Road, Shanghai 200092 (China); Zhao, Xinyuan [Department of Building Engineering, Tongji University, No. 1239 Siping Road, Shanghai 200092 (China); Tang, Dongsheng [Guangdong Electric Power Design Institute, No. 1 Tianfeng Road, Guangzhou, Guangdong 510663 (China)

    2013-05-15

    Highlights: ► Ground vibration due to the collapse of a huge cooling tower was predicted. ► Accidental loads with different characteristics caused different collapse modes. ► Effect of ground vibration on the nuclear-related facilities cannot be ignored. -- Abstract: A comprehensive approach is presented in this study for the prediction of the ground vibration due to the collapse of a 235 m high cooling tower, which can be caused by various accidental loads, e.g., explosion or strong wind. The predicted ground motion is to be used in the safety evaluation of nuclear-related facilities adjacent to the cooling tower, as well as the plant planning of a nuclear power station to be constructed in China. Firstly, falling weight tests were conducted at a construction site using the dynamic compaction method. The ground vibrations were measured in the form of acceleration time history. A finite element method based “falling weight-soil” model was then developed and verified by field test results. Meanwhile, the simulated collapse processes of the cooling tower under two accidental loads were completed in a parallel study, the results of which are briefly introduced in this paper. Furthermore, based on the “falling weight-soil” model, “cooling tower-soil” models were developed for the prediction of the ground vibrations induced by two collapse modes of the cooling tower. Finally, for a deep understanding of the vibration characteristics, a parametric study was also conducted with consideration of different collapse profiles, soil geologies as well as the arrangements of an isolation trench. It was found that severe ground vibration occurred in the vicinity of the cooling tower when the collapse happened. However, the vibration attenuated rapidly with the increase in distance from the cooling tower. Moreover, the “collapse in integrity” mode and the rock foundation contributed to exciting intense ground vibration. By appropriately arranging an isolation

  11. IT - OSRA: applying ensemble simulations to estimate the oil spill hazard associated to operational and accidental oil spills

    Science.gov (United States)

    Sepp Neves, Antonio Augusto; Pinardi, Nadia; martins, Flavio

    2016-04-01

    Every year, 270,000 tonnes of oil are estimated to be spilled in the ocean by vessel operations (e.g. tank washing, leakage of lubricants) and the so called operational spills are typically associated with small volumes and high occurrence rate. Vessel-related accidental spills (e.g. collisions, explosions) seldom occur and usually involve high volumes of oil, accounting for about 100,000 tonnes/year. The occurrence of accidental spills and their impacts have been well documented in the available literature. On the other hand, occurrence rates of operational spills and the effects they have on the marine and coastal environments remain very uncertain due to insufficient sampling effort and methodological limitations. Trying to foresee when and where an oil spill will occur in a certain area, its characteristics and impacts is, at present, impossible. Oil spill risk assessments (OSRAs) have been employed in several parts of the globe in order to deal with such uncertainties and protect the marine environment. In the present work, we computed the oil spill risk applying ensemble oil spill simulations following an ISO-31000 compliant OSRA methodology (Sepp Neves et al. , 2015). The ensemble experiment was carried out for the Algarve coast (southern Portugal) generating a unique data set of 51,200 numerical oil spill simulations covering the main sources of uncertainties (i.e. where and when the spill will happen and oil spill model configuration). From the generated data set, the risk due to accidental and operational spills was mapped for the Algarve municipalities based on the frequency and magnitude (i.e. concentrations) of beaching events and the main sources of risk were identified. The socioeconomic and environmental dimensions of the risk were treated separately. Seasonal changes in the risk index proposed due to the variability of meteo-oceanographic variables (i.e. currents and waves) were also quantified.

  12. Individual and Bivalent Vaccines Based on Alphavirus Replicons Protect Guinea Pigs against Infection with Lassa and Ebola Viruses

    OpenAIRE

    Pushko, Peter; Geisbert, Joan; Parker, Michael; Jahrling, Peter; Smith, Jonathan

    2001-01-01

    Lassa and Ebola viruses cause acute, often fatal, hemorrhagic fever diseases, for which no effective vaccines are currently available. Although lethal human disease outbreaks have been confined so far to sub-Saharan Africa, they also pose significant epidemiological concern worldwide as demonstrated by several instances of accidental importation of the viruses into North America and Europe. In the present study, we developed experimental individual vaccines for Lassa virus and bivalent vaccin...

  13. La responsabilidad civil del empresario por daños y perjuicios derivados de accidente de trabajo

    OpenAIRE

    Monerri Guillén, Concepción

    2015-01-01

    *Introducción: La presente tesis doctoral bajo el título “La responsabilidad civil del empresario por daños y perjuicios derivados del accidente de trabajo”, ha suscitado gran interés en la doctrina y jurisprudencia de las Salas Primera y Cuarta del Tribunal Supremo ante la falta de criterios unánimes a la hora de enjuiciar la cuestión. El órgano competente para el enjuiciamiento, la valoración del daño y, el descuento de cantidades provenientes de la Seguridad Social, daban lugar al llamado ...

  14. La trombectomía mecánica en el tratamiento de accidentes cerebrovasculares (ACV) en la fase aguda

    OpenAIRE

    Alain Bonafe

    2013-01-01

    En Francia, la incidencia anual de accidentes cerebro vasculares (ACV) es de 1.6 a 2.4 por cada mil (1.000) personas, es decir entre 100.000 y 145.000 por año, con una mortalidad del 15 al 20% al cabo del primer mes y un 75% de personas sobrevivientes con secuelas. El tratamiento de preferencia es la Trombólisis IV (Intra Venosa) con rt-PA (Recombinant Tissue Plasminogen Activator - Activador del Plasminógeno Tisular Recombinante), el cual tiene una ventana de eficacia...

  15. Aprendizajes del Accidente de San Juan Ixhuatepec-México Learning from the Accident in San Juan Ixhuatepec-Mexico

    OpenAIRE

    Antioco López-Molina; Richart Vázquez-Román; Christian Díaz-Ovalle

    2012-01-01

    El índice Dow de fuego y explosión y la metodología del análisis cuantitativo del riesgo son aplicados para analizar uno de los accidentes más desafortunados en la historia mexicana: la explosión de tanques de almacenamiento de gas en la planta de San Juan Ixhuatepec en México. Estimaciones adicionales de la sobrepresión y radiación térmica producida durante el siniestro son llevadas a cabo para explicar el efecto dominó producido como consecuencia del incidente. Estas estimaciones dan eviden...

  16. Prevalencia de accidentes punzocortantes y material biológico en estudiantes de Odontología (UNLP)

    OpenAIRE

    2015-01-01

    Introducción: La Odontología dentro del marco de las Ciencias de la Salud, es considerada una profesión de alto riesgo. Con la aparición de nuevas enfermedades transmisibles es imprescindible utilizar la educación para promover un modo de vida sana. La falta de conocimiento de las normas de bioseguridad sería una de las causas más importantes de accidentes con elementos punzocortantes y material biológico. Consideramos que en la etapa de formación del alumno, la bioseguridad debe constituir u...

  17. Falls related to accidental deactivation of deep brain stimulators in patients with Parkinson's disease living in long term care facilities.

    Science.gov (United States)

    Tousi, Babak; Wilson, Kathy

    2013-01-01

    This case series highlights three patients with Parkinson's disease residing at nursing home facilities whose deep brain stimulators were accidentally deactivated for varying lengths of time, which was associated with an increase in falls. In all three cases, neither the patients nor the caregivers were aware of the random deactivations/reactivations. We propose a specific care plan for these patients that includes further education of caregivers regarding deep brain stimulators and regular checks of the review device, especially when there is concern about a patient's mobility or balance that is out of character.

  18. Función pulmonar en sujetos con hemiparesia crónica secundaria a un accidente cerebrovascular

    OpenAIRE

    Guerrero Gómez, Alba

    2016-01-01

    Antecedentes: las Enfermedades Cerebrovasculares se sitúan como la primera causa de muerte entre las mujeres y la tercera en hombres a nivel nacional. Son numerosas las secuelas que pueden sufrir los supervivientes, entre las que se encuentran las alteraciones del control motor y del tono muscular. Estas son las que hacen plantearse el grado de afectación de la musculatura implicada en la ventilación tras un Accidente Cerebrovascular, ya sea de manera directa o mediante la alteración de las c...

  19. Muerte prematura por accidente cerebrovascular y condición socioeconómica en la Argentina

    Directory of Open Access Journals (Sweden)

    Mauricio Monsalvo

    2016-04-01

    Full Text Available Introducción: La asociación entre mortalidad por accidente cerebrovascular y el nivel socioeconómico está escasamente descripta en Argentina. Objetivos: Describir la evolución temporal de la mortalidad por accidente cerebrovascular y su asociación con el nivel socioeconómico en Argentina entre 2000 y 2011. Material y métodos: Se realizó un estudio ecológico longitudinal. La mortalidad se cuantificó mediante tasas estandarizadas por edad y sexo, y el nivel socioeconómico mediante quintilos de necesidades básicas insatisfechas. Las unidades de observación fueron los departamentos de Argentina. La asociación entre mortalidad y nivel socioeconómico se evaluó utilizando un modelo de regresión de Poisson para datos de panel. Resultados: La mortalidad por accidente cerebrovascular aumentó progresivamente entre los quintilos de nivel socioeconómico (26,2, 28,4, 30,5, 34,5 y 36,9 por 100.000 personas, para los quintilos 1 a 5, respectivamente en el año 2000. La mortalidad en todos los grupos de nivel socioeconómico disminuyó, aunque persistieron diferencias entre ellos (17,2, 18,5, 20,1, 22,1 y 25,3 por 100.000 personas, para los quintilos 1 a 5, respectivamente en el año 2011. Las razones de tasas de incidencias fueron 1,15 (IC 95% 1,09 a 1,22; p<0,001, 1,27 (IC 95% 1,21 a 1,34; p<0,001, 1,32 (IC 95% 1,26 a 1,39; p<0,001, y de 1,48 (IC 95% 1,41 a 1,56; p<0,001, para los quintilos 2 a 5. Conclusiones: Los resultados sugieren una asociación inversa entre el nivel socioeconómico y la mortalidad por accidente cerebrovascular. Además, persistió una diferencia de mortalidad entre los niveles socioeconómicos durante el período de estudio.

  20. Accidentes de carretera y su relación con cansancio y somnolencia en conductores de ómnibus.

    OpenAIRE

    Rosales Mayor, Edmundo; Egoavil Rojas, Martha Teresa; Durand Vila, Ivette Solange; Natalie, Montes Ccaccro Evelyn; Flores Herrera, Rosario Edith; Rivera García, Silvia Lucía; Alonso Cueva, Carla Gabriela; Merino Baquerizo, Lucía Leonor; Rey de Castro Mujica, Jorge

    2012-01-01

    Objetivo: Determinar el nivel de cansancio, somnolencia y hábitos de conducción de conductores de ómnibus y explorar su relación con accidentes de carretera en el terminal terrestre de Huancayo, Perú. Material y métodos: Estudio transversal. Se aplicó un cuestionario pre-validado y la Escala de Somnolencia de Epworth (ESE). Resultados: De los 100 conductores, todos ellos fueron varones. El día que trabajaban dormían 6,8±2,6 horas. El 47% había dormido menos de 6 horas en las últimas 24 horas....

  1. Management of Accidental Finding of Ascaris Lumbricoides During Emergent Abdominal Surgery: A Case Report and Review of the Literature.

    Science.gov (United States)

    Esfehani, Maryam Hassan; Jahanshahi, Abdolhadi; Karimi, Amirhossein

    2016-01-01

    Ascariasis lumbricoides is the most common soil-transmitted helminth worldwide and most often is asymptomatic, although it can present with abdominal pain, malabsorption and growth failure, complete or partial obstraction in small bowel and biliary system and etc. Accidental encounters with ascaris during emergent abdominal surgeries are very rare and have been reported in less than a handful of papers. In this report, we describe this rare event from a country with low prevalence of this infection, and then review the literatures and clarify the possible challenges for surgeons during operation and postoperative follow-up.

  2. The political economy of rationing health care in England and the US: the 'accidental logics' of political settlements.

    Science.gov (United States)

    Bevan, Gwyn; Brown, Lawrence D

    2014-07-01

    This article considers how the 'accidental logics' of political settlements for the English National Health Service (NHS) and the Medicare and Medicaid programmes in the United States have resulted in different institutional arrangements and different implicit social contracts for rationing, which we define to be the denial of health care that is beneficial but is deemed to be too costly. This article argues that rationing is designed into the English NHS and designed out of US Medicare; and compares rationing for the elderly in the United States and in England for acute care, care at the end of life, and chronic care.

  3. Estudio clínico del proceso conductual de la emergencia del coma grave por accidente cerebrovascular

    OpenAIRE

    2007-01-01

    Objetivos: Estudiar el proceso de la emergencia del coma en pacientes en coma grave por accidente cerebrovascular (ACV). Método: Se han evaluado a 32 pacientes ingresados en una unidad de cuidados intensivos por un coma de origen cerebrovascular. Se ha realizado un seguimiento diario por neuropsicólogos e intensivistas y monitorizado el despertar del coma mediante 8 escalas de evalua ... ción clínica de los niveles de coma. Se han analizado las variables: edad, género, residencia, índice prem...

  4. Un análisis en los accidentes cerebrovasculares una nueva mirada a los factores de riesgo para la aparición de la enfermedad. Un análisis en los accidentes cerebrovasculares

    Directory of Open Access Journals (Sweden)

    Luis Felipe Herrera Jiménez

    2013-10-01

    Full Text Available ResumenLa presencia o no de factores psicológicos de riesgo para la aparición de distintas enfermedades continúa siendo un tema controvertido en las ciencias médicas y psicológicas, quizás por las dificultades que se presentan en el momento de su evaluación. No obstante, ya se han realizado primeras miradas en este sentido, presentando la siguiente investigación en personas con accidente cerebrovascular, como un análisis preliminar experimental; que más que brindar datos definitorios, permita a la vez, abrir nuevos caminos hacia la búsqueda de la multideterminación de los procesos patológicos. Con el objetivo central de determinar factores psicológicos de riesgo para la aparición de los accidentes cerebrovasculares, se establecieron dos grupos de estudio y testigo, a los cuales se le aplicaron el test de depresión Zung-Conde, el IDARE, el cuestionario de conductas de enfrentamiento y el examen neuropsicológico de Anne-Lise Crhistensen. Se pudo definir la existencia de factores más relacionados con características personológicas, factores externos fundamentalmente provenientes del medio y factores producto de esta interacción como lo constituyen el estrés y la ansiedad. (Duazary 2006; 1: 24 - 31 

  5. Accidentes de trabajo en el Hospital Clínico de la Universidad de Chile durante el año 2007

    Directory of Open Access Journals (Sweden)

    Carlos Valdés

    2009-01-01

    Full Text Available Objetivo, Conocer el número de los accidentes laborales en el Hospital Clínico de la Universidad de Chile (HCUCH el año 2007 y su caracterización de acuerdo a variables como, sexo, edad, tipo de lesión, día de la semana, mes del año, cargo desempeñado y días perdidos. Diseño, Estudio descriptivo, transversal, retrospectivo y observacional. Lugar, Hospital Clínico de la Universidad de Chile (HCUCH. Participantes, Accidentes laborales reportados entre el 1 de Enero y el 31 de Diciembre del 2007. Intervención, Se utilizó la base de datos del Registro de Notificación de Accidentes Laborales, proporcionada por el Departamento de Prevención de Riesgos del HCUCH Principales medidas de Resultados, Porcentajes y Medidas de Tendencia Central, tabuladas en una base de datos con ayuda del programa Microsoft Excel 2003 para Windows ®. Resultados: Se observan 104 accidentes laborales, con un mayor número de eventos en el personal femenino (69,2%, en el rango etareo de 30-39 años (34,3%, el tipo de lesión más frecuente fueron las contusiones/policontusiones (39,4%, el grupo más accidentado fue los auxiliares y técnicos (71.1%. El estudio por días de la semana revela que hay más accidentes los días miércoles y jueves (43,27% y los meses del año con más accidentes fueron enero, agosto y diciembre. La mayor cantidad de accidentes laborales comprometen entre 1 a 5 días perdidos. Conclusiones: Durante el año 2007, se pesquisó 104 accidentes laborales, lo que significó 804 días de ausentismo. Este estudio muestra que el sexo femenino, tener entre 30-39 años y ejercer como auxiliar o técnico fueron factores de asociados al incremento de los accidentes laborales.

  6. Accidente ofídico en animales de pastoreo: acercamiento epidemiológico, clínico y de manejo

    Directory of Open Access Journals (Sweden)

    Sebastián Estrada-Gómez

    2014-06-01

    Full Text Available En animales de pastoreo, el reporte de accidentes ofídicos es muy bajo y, además, presenta un amplio subregistro. A pesar de esto, es de gran utilidad conocer la incidencia de estos accidentes, pues son de gran importancia por las pérdidas económicas que pueden causar en el sector pecuario. Los accidentes por serpientes venenosas, tanto de la familia Viperidae como Elapidae, en caballos y ganado vacuno son frecuentes en muchos lugares del mundo, debido al aumento en la destinación de las tierras para la actividad ganadera. Colombia no es ajena a ello; sin embargo, el registro de este tipo de accidentalidad es muy bajo. En los diferentes reportes de accidentes ofídicos en animales, se ha observado que las principales manifestaciones sistémicas están caracterizadas por complicaciones cardiacas, hemodinámicas y neurotóxicas. Igualmente, se observan efectos locales, los cuales se caracterizan por presencia de hemorragias locales, edema y necrosis. El tratamiento específico utilizado en los accidentes por serpientes es la seroterapia, que consta de inmunoglobulinas G (Sueros IgG completas o fraccionadas (Faboterápicos Fab o Fab2, específicas para un género o especie.

  7. Distribución espacial de los accidentes y enfermedades relacionados con el trabajo en el Perú, 2012-2014

    Directory of Open Access Journals (Sweden)

    Akram Hernández-Vásquez

    2016-01-01

    Full Text Available Se analizaron geoespacialmente los accidentes, incidentes peligrosos y enfermedades ocupacionales que se reportaron a nivel regional en el Perú (2012-2014. 52 887 eventos se notificaron entre accidentes de trabajo (93%, incidentes peligrosos (5,1%, enfermedades ocupacionales (1% y accidentes mortales (0,9%. Se evidenciaron altas tasas de accidentes mortales en Pasco, Callao, Lima, Moquegua y Arequipa. Callao y Lima son las regiones con tasas más altas de accidentes de trabajo. Las mayores tasas de incidentes peligrosos se reportaron en Arequipa, Callao, Lima, Ica y Piura. Las enfermedades ocupacionales se distribuyeron con altas tasas en Huancavelica, Ancash, Pasco, Callao y Cusco. La explotación de minas y canteras (49,2%; seguida por la industria manufacturera (23,4%; y, la construcción (8% son las actividades económicas que concentraron elevadas tasas de enfermedades ocupacionales. Se concluye que existen altas tasas y patrones espaciales comunes de accidentabilidad en el Perú que pueden servir para enfocar intervenciones.

  8. General guidelines for medically screening mixed population groups potentially exposed to nerve or vesicant agents

    Energy Technology Data Exchange (ETDEWEB)

    Watson, A.P.; Munro, N.B. [Oak Ridge National Lab., TN (United States); Sidell, F.R. [Army Medical Research Inst. of Chemical Defense, Aberdeen Proving Ground, MD (United States); Leffingwell, S.S. [Centers for Disease Control, Atlanta, GA (United States). Center for Environmental Health and Injury Control

    1992-01-01

    A number of state and local planners have requested guidance on screening protocols and have expressed interest in sampling body fluids from exposed or potentially exposed individuals as a means of estimating agent dose. These guidelines have been developed to provide a clear statement that could be used by state and local emergency response personnel in the event of a nerve or vesicant agent incident resulting in off-post contamination; maximum protection from harm is the goal. The assumption is that any population group so exposed would be heterogeneous for age, gender, reproductive status, and state of health.

  9. Accidental phosphine gas poisoning with fatal myocardial dysfunction in two families.

    Science.gov (United States)

    Akhtar, Saleem; Rehman, Arshalooz; Bano, Surraya; Haque, Anwarul

    2015-05-01

    Aluminum phosphide is commonly used as a rodenticide and insecticide and is one of the most fatal poisons. The active ingredient is Phosphine gas which inhibits cytochrome oxidase and cellular oxygen utilization. The clinical symptoms are due to multiorgan involvement including cardiac toxicity which is the most common cause of mortality. Severity of clinical manifestations depends upon the amount of the gas to which a person is exposed. There is no specific antidote available. High index of suspicion and early aggressive treatment is the key to success. We report 2 cases of aluminum phosphide toxicity in 2 families due to incidental exposure after fumigation.

  10. Una nueva metodología para la predicción de la gravedad en los accidentes industriales aplicando el análisis histórico

    OpenAIRE

    Carol Llopart, Sergio

    2001-01-01

    La presente tesis va encaminada al estudio de la gravedad de los accidentes industriales con sustancias peligrosas mediante la utilización del análisis histórico de accidentes. Su objetivo final es utilizar el tratamiento cuantitativo de dicho análisis para desarrollar una metodología que permita predecir la gravedad de los accidentes.Los factores de riesgo que determinan la mayor o menor gravedad de los accidentes son tantos y tan complejos, que las aproximaciones determinísticas tradiciona...

  11. DNA damage and cytotoxicity in pathology laboratory technicians exposed to organic solvents

    Directory of Open Access Journals (Sweden)

    TATIANE DE AQUINO

    2016-03-01

    Full Text Available The aim of this study was to evaluate potential DNA damage and cytotoxicity in pathology laboratory technicians exposed to organic solvents, mainly xylene. Peripheral blood and buccal cells samples were collected from 18 technicians occupationally exposed to organic solvents and 11 non-exposed individuals. The technicians were sampled at two moments: Monday and Friday. DNA damage and cytotoxicity were evaluated using the Comet Assay and the Buccal Micronucleus Cytome assay. Fifteen subjects (83.5% of the exposed group to solvents complained about some symptom probably related to contact with vapours of organic solvents. DNA damage in the exposed group to solvents was nearly 2-fold higher on Friday than on Monday, and in both moments the individuals of this group showed higher levels of DNA damage in relation to controls. No statistical difference was detected in buccal cell micronucleus frequency between the laboratory technicians and the control group. However, in the analysis performed on Friday, technicians presented higher frequency (about 3-fold of karyolytic and apoptotic-like cells (karyorrhectic and pyknotic in relation to control group. Considering the damage frequency and the working time, a positive correlation was found in the exposed group to solvents (r=0.468; p=0.05. The results suggest that pathology laboratory workers inappropriately exposed to organic solvents have increased levels of DNA damage.

  12. Communication: Effect of accidental mode degeneracy on Raman intensity in 2D materials: Hybrid functional study of bilayer phosphorene.

    Science.gov (United States)

    Sun, Yi-Yang; Zhang, Shengbai

    2016-07-14

    Bulk black phosphorus has two optical phonon modes labeled as Ag (2) and B2u, respectively, that are nearly degenerate in frequency. However, density functional theory calculations using local or semi-local functionals cannot reproduce this degeneracy. Here, we propose a hybrid functional approach aided by van der Waals (vdW) force fields, which can accurately describe the lattice dynamic and electronic properties of both bulk and few-layer black phosphorus (phosphorene). Using this approach we show that in bilayer phosphorene, the two Raman modes derived from the B2u and Ag (2) modes could exhibit strong resonance as a result of the accidental degeneracy so that both modes could be observed in Raman experiment. Without the mode degeneracy, however, the Raman intensity of the B2u-derived mode would be too weak to be observed. We further show that the accidental degeneracy is correlated to the applied strain, which enables Raman spectroscopy to be a powerful tool for characterizing built-in strains in 2D materials, e.g., due to the interaction with substrates, which has emerged as an important issue in vdW epitaxy.

  13. A genomic survey of positive selection in Burkholderia pseudomallei provides insights into the evolution of accidental virulence.

    Directory of Open Access Journals (Sweden)

    Tannistha Nandi

    2010-04-01

    Full Text Available Certain environmental microorganisms can cause severe human infections, even in the absence of an obvious requirement for transition through an animal host for replication ("accidental virulence". To understand this process, we compared eleven isolate genomes of Burkholderia pseudomallei (Bp, a tropical soil microbe and causative agent of the human and animal disease melioidosis. We found evidence for the existence of several new genes in the Bp reference genome, identifying 282 novel genes supported by at least two independent lines of supporting evidence (mRNA transcripts, database homologs, and presence of ribosomal binding sites and 81 novel genes supported by all three lines. Within the Bp core genome, 211 genes exhibited significant levels of positive selection (4.5%, distributed across many cellular pathways including carbohydrate and secondary metabolism. Functional experiments revealed that certain positively selected genes might enhance mammalian virulence by interacting with host cellular pathways or utilizing host nutrients. Evolutionary modifications improving Bp environmental fitness may thus have indirectly facilitated the ability of Bp to colonize and survive in mammalian hosts. These findings improve our understanding of the pathogenesis of melioidosis, and establish Bp as a model system for studying the genetics of accidental virulence.

  14. Final Report: Safety of Plasma Components and Aerosol Transport During Hard Disruptions and Accidental Energy Release in Fusion Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Bourham, Mohamed A.; Gilligan, John G.

    1999-08-14

    Safety considerations in large future fusion reactors like ITER are important before licensing the reactor. Several scenarios are considered hazardous, which include safety of plasma-facing components during hard disruptions, high heat fluxes and thermal stresses during normal operation, accidental energy release, and aerosol formation and transport. Disruption events, in large tokamaks like ITER, are expected to produce local heat fluxes on plasma-facing components, which may exceed 100 GW/m{sup 2} over a period of about 0.1 ms. As a result, the surface temperature dramatically increases, which results in surface melting and vaporization, and produces thermal stresses and surface erosion. Plasma-facing components safety issues extends to cover a wide range of possible scenarios, including disruption severity and the impact of plasma-facing components on disruption parameters, accidental energy release and short/long term LOCA's, and formation of airborne particles by convective current transport during a LOVA (water/air ingress disruption) accident scenario. Study, and evaluation of, disruption-induced aerosol generation and mobilization is essential to characterize database on particulate formation and distribution for large future fusion tokamak reactor like ITER. In order to provide database relevant to ITER, the SIRENS electrothermal plasma facility at NCSU has been modified to closely simulate heat fluxes expected in ITER.

  15. Normal neurologic and developmental outcome after an accidental intravenous infusion of expressed breast milk in a neonate.

    LENUS (Irish Health Repository)

    Ryan, C Anthony

    2012-02-03

    Here we describe a premature male infant who was accidentally given 10 mL of expressed breast milk intravenously over a 3.5-hour period. Having survived this event with supportive care, this boy was attending regular school with no obvious neurologic or learning difficulties at 6 years of age. In 1998, after a query on an e-mail discussion group for health care providers in neonatology (NICU-net), we were informed of 8 similar events that proved fatal in 3 infants. A root-cause analysis revealed that accidental intravenous administration of breast milk or formula can be avoided by the use of color-coded enteral-administration sets with Luer connections that are not compatible with intravenous cannulas. The addition of methylene blue to feeds, or bolus enteral feeds (instead of continuous gastric feedings), may also help prevent such errors. These cases show the value of gathering information about rare but important events through a neonatal network. In addition, they confirm that prevention of medical error should focus on faulty systems rather than faulty people.

  16. Communication: Effect of accidental mode degeneracy on Raman intensity in 2D materials: Hybrid functional study of bilayer phosphorene

    Science.gov (United States)

    Sun, Yi-Yang; Zhang, Shengbai

    2016-07-01

    Bulk black phosphorus has two optical phonon modes labeled as Ag2 and B2u, respectively, that are nearly degenerate in frequency. However, density functional theory calculations using local or semi-local functionals cannot reproduce this degeneracy. Here, we propose a hybrid functional approach aided by van der Waals (vdW) force fields, which can accurately describe the lattice dynamic and electronic properties of both bulk and few-layer black phosphorus (phosphorene). Using this approach we show that in bilayer phosphorene, the two Raman modes derived from the B2u and Ag2 modes could exhibit strong resonance as a result of the accidental degeneracy so that both modes could be observed in Raman experiment. Without the mode degeneracy, however, the Raman intensity of the B2u-derived mode would be too weak to be observed. We further show that the accidental degeneracy is correlated to the applied strain, which enables Raman spectroscopy to be a powerful tool for characterizing built-in strains in 2D materials, e.g., due to the interaction with substrates, which has emerged as an important issue in vdW epitaxy.

  17. Hipotermia acidental em um país tropical Accidental hypothermia cases in a tropical country

    Directory of Open Access Journals (Sweden)

    Valdir Golin

    2003-09-01

    hypothermia prevailed in the male sex with 75.9%. As age group prevailed the age between 30 and 59 years. In 70.3% of the patients the central temperature went lower than 32°C, and in 26.4% of these, the temperature was lower than 28°C. The association with infectious processes happened in 76.8% of the cases. The patients with mild hypothermia answered better at therapeutics (96.8% when compared with the moderate hypothermic (72.1% and serious (87.5% patients. The Osborn's wave was present in 42.6% of the patients. The general mortality was 38.2%. CONCLUSIONS: The accidental hypothermia in Emergency Services from Tropical Country is an undeniable fact. The paramedic and medics should be alert and trained to recognize this disease of high morbidity and mortality. The mortality increases with the presence of associated diseases, particularly infectious processes, malnutrition and chronic alcoholism.

  18. Optimisation of the digital radiographic imaging of suspected non-accidental injury

    Science.gov (United States)

    Offiah, Amaka

    Aim: To optimise the digital (radiographic) imaging of children presenting with suspected non-accidental injury (NAI). Objectives: (i) To evaluate existing radiographic quality criteria, and to develop a more suitable system if these are found to be inapplicable to skeletal surveys obtained in suspected NAI. (ii) To document differences in image quality between conventional film-screen and the recently installed Fuji5000R computed radiography (CR) system at Great Ormond Street Hospital for Children, (iii) To document the extent of variability in the standard of skeletal surveys obtained in the UK for suspected NAI. (iv) To determine those radiographic parameters which yield the highest diagnostic accuracy, while still maintaining acceptable radiation dose to the child, (v) To determine how varying degrees of edge-enhancement affect diagnostic accuracy. (vi) To establish the accuracy of soft compared to hard copy interpretation of images in suspected NAI. Materials and Methods: (i) and (ii) Retrospective analysis of 286 paediatric lateral spine radiographs by two observers based on the Commission of European Communities (CEC) quality criteria, (iii) Review of the skeletal surveys of 50 consecutive infants referred from hospitals throughout the United Kingdom (UK) with suspected NAI. (iv) Phantom studies. Leeds TO. 10 and TO. 16 test objects were used to compare the relationship between film density, exposure parameters and visualisation of object details, (iv) Clinical study. Anteroposterior and lateral post mortem skull radiographs of six consecutive infants were obtained at various exposures. Six observers independently scored the images based on visualisation of five criteria, (v) and (vi) A study of diagnostic accuracy in which six observers independently interpreted 50 radiographs from printed copies (with varying degrees of edge-enhancement) and from a monitor. Results: The CEC criteria are useful for optimisation of imaging parameters and allow the detection

  19. Impact assessment of the Fukushima Nuclear Power Plant accidental emission on the Barents Sea ecosystem

    Science.gov (United States)

    Matishov, Gennady; Ilyin, Gennady; Kasatkina, Nadezhda; Usiagina, Irina; Pavelskaya, Elena

    2013-04-01

    The traces of emissions from the Fukushima-1 NPP in atmospheric aerosols of the Kola Peninsula near the Barents Sea coast were detected by radiation monitoring stations of the Murmansk Division of the Hydrometeorological Survey MDHMS in the end of March 2011. From the end of March 2011 until April 20, 131I, 134Cs, 132Te, 137Cs radioisotopes were observed in the atmospheric air. The major role was played by 131I isotope; its peak concentrations were (140-220)×10-6 Bq/m3, and it was recorded for several days (March 30-April 1), then radioactivity decreased. 134Cs, 132Te, and 137Cs isotopes were recorded episodically. The supply of radionuclides from accidental emissions into the atmosphere of the Kola Peninsula did not cause significant changes in gamma-radiation dose rates EDR. This value remained within the limits of the average long-term norm, and continued so during the following months 2011. Possible dry and humid precipitation of radionuclides within the water catchment area and in the marine basin did not influence on radioecological state in both coastal and off-shore parts of the Barents Sea. Short-lived isotopes as 131I, 134Cs, and 132Te, which might confidently indicate a trace from the Fukushima-1 NPP, have not been recorded in the samples. In 2011-1012 volumetric activity of 137Cs and 90Sr in water of the Barents Sea (section VI along the meridian 33° 30' N) varied in the range of 1.3-2.5 and 3.4-6.3 Bq/m3, respectively. Radioactive contamination of bottom sediments in the Barents Sea was very low. The specific activity of 137Cs varied from 1 to 8 Bq/kg, the activity of 90Sr did not exceed 4 Bq/kg. Investigations of macrophyte algae showed extremely low concentrations of artificial radionuclides. The specific activity of 137Cs in most samples was at the level of trace concentrations, from 0.2 to 1.5 Bq/kg of dry mass. The content of 90Sr in algae changed in the range of 0.4-4.1 Bq/kg of dry mass. In soft tissues of bivalves Mytilus edulis collected on

  20. Accidental Predissociation: A Special Case of Photo-Induced Isotope Fractionation Effect and Possible Occurrence in Nature

    Science.gov (United States)

    Chakraborty, S.; Thiemens, M. H.

    2009-12-01

    Photo-Induced Isotope Fractionation Effects (PHIFE) are known to produce isotopic frac-tionation in some photo-dissociating molecules (1-2). The PHIFE formalism is based on the Born-Oppenheimer approximation and the Reflection Principle. The isotopic fractionation arises principally from the spectral shift induced by the small difference in zero point energy between isotopologues and the contraction of the wave function due to isotopic substitution, consequently, the associated isotopic fractionations depends on the reduced mass of the isotopically substi-tuted species. The PHIFE formalism is only applicable to the molecules which undergo direct photo-dissociation that possess continuous absorption spectra. Simple molecules (N2, O2, CO) however do not follow a direct dissociation pathway and dissociate through an indirect process termed predissociation, which occurs when the molecule is excited to a quasi-bound state energetically above the dissociation continuum. The PHIFE formalism is not applicable when the absorption spectra are discrete. The assumption that the lightest isotopologues are preferentially predissociated is only valid for restricted predissociation cases. There is a special case of predissociation known as ‘accidental predissociation’ (3), which takes place through an intermediate bound state in two steps (i) leakage to an intermediate bound state (coupled through spin orbit interaction) and, (ii) predissociation to a third quasi-bound state from the intermediate state. Line broadening at an accidental predissociation is a function of the magnitude of coupling matrix elements and the linewidths are strongly influenced by isotopic substitution (4). An anomalous isotopic effect in accidental predissociation was spectroscopically observed in CO (5), N2 (4) and BeH (6). We measured the isotopic fractionation for the first time in two accidental predissociating states of CO through VUV photodissociation using the 9.0.2 beamline at ALS (7-8). In

  1. Accidentes atendidos en un área básica de salud de girona, españa

    Directory of Open Access Journals (Sweden)

    Soriano Suárez Elena

    2002-01-01

    Full Text Available Fundamentos: Los accidentes constituyen una patología poco estudiada en el ámbito de la Atención Primaria. Son una de las consultas más frecuentes en los servicios de urgencias y los Centros de Atención Primaria realizan la primera asistencia a la mayoría de los accidentados. Conocer la incidencia y las características clínico-epidemiológicas de los accidentes atendidos en una Área Básica de Salud puede aportar información sobre cuáles pueden ser susceptibles de actividades de prevención. Métodos: Diseño: estudio descriptivo. Emplazamiento: atención primaria. Muestra: todos los pacientes (389 que fueron atendidos por accidente en el Centro de Atención Primaria, entre octubre-98 y mayo-99. Variables: edad, sexo, lugar del accidente, tipo de lesión, localización, agentes implicados, intencionalidad, pruebas complementarias, tratamiento y derivación. Análisis estadísticos: estimación de medias, desviación estándar, estimación de proporciones e intervalos de confianza del 95%. Resultados: Incidencia: 4,1% (IC95%: 3,7-4,5%. Sexo: varones 59% (IC95%:54,2-64% y mujeres 40,9% (IC95%: 36-45,8%. Edad: menores de 20 años, el 50,4% (IC95%:45,4-55,4%;.Actividad de mayor accidentalidad: ocio 24,4% (IC95%: 20,2-28,7%. Lugar: hogar 36,2% (IC95%: 31,5-41%. Lesión más frecuente: contusiones 39,6% (IC95%:34,7-44,4%.Localización más frecuente: extremidad superior 37,5% (IC95%: 32,7-42,3%; Agente mayoritariamente implicado: herramientas y máquinas: 15,9% (IC95%:12,3-19,6%. El 92,2% (IC95%: 89,3-94,7% fueron casuales. Tipo de visita: el 83,3% (IC95%: 79,6-87% fueron atendidos con carácter urgente; el 79,5% (IC95%:75,4-83,5% recibió tratamiento con cura y/o fármacos. El 9,8% (IC95%:6,8-12,7% requirió derivación hospitalaria, Un 13,3% (IC95%: 0-16,7% requirió pruebas complementarias. Conclusiones: El mayor porcentaje de accidentalidad se da en población joven, por lo que se evidencia la necesidad de incorporar intervenciones de

  2. Review of medical findings in a Marshallese population twenty-six years after accidental exposure to radioactive fallout

    Energy Technology Data Exchange (ETDEWEB)

    Conard, R.A.; Paglia, D.E.; Larsen, P.R.

    1980-01-01

    In March 1954, radioactive debris from a thermonuclear weapon test at Bikini Atoll deviated from predicted trajectories and contaminated several atolls in the northern Marshall Islands. As a result, 239 native inhabitants of these islands along with 28 American servicemen and 23 Japanese fishermen received variably severe exposures to diverse ionizing radiations. Fallout material consisted largely of mixed fission products with small amounts of neutron-induced radionuclides and minimal amounts of fissionable elements, producing a complex spectrum of electromagnetic and particulate radiation. Individuals were exposed to deeply penetrating, whole-body gamma irradiation, to internal radiation emitters assimilated either by inhalation or by ingestion of contaminated water and food, and to direct radiation from material accumulating on body surfaces. That accident initiated a cascade of events, medical, social and political, which continue in varying forms to this day. Most of these have been discussed in the open medical literature and in periodic reports issued by the medical team headquartered at Brookhaven National Laboratory. This report attempts to summarize some of the principal findings of medical significnce that have been observed during the subsequent 26 years with particular emphasis on the last six years.

  3. 2006-2011年五华县居民意外死亡分析%Accidental Death of Residents in Wuhua County, 2006-2011

    Institute of Scientific and Technical Information of China (English)

    沈超华; 周荣群; 陈青山; 张聪

    2013-01-01

    目的 了解五华县居民意外死亡情况及变化趋势,为制定相应防控策略提供科学依据.方法 对2006-2011年五华县全人群死因监测资料中的意外死亡资料进行整理分析.结果 2006-2011年意外死亡2 328人,年均死亡率30.18/10万,占全死因的6.46%,居全死因第5位.男、女性意外死亡率分别为39.38/10万和20.43/10万,男性高于女性.前5位意外死因是机动车辆交通事故、淹死、自杀、意外跌落和意外中毒.除0岁组外,意外死亡率随年龄的增长而上升,0~4岁和5~14岁年龄段人群主要意外死因为淹死,分别占该年龄段意外死亡的63.58%和57.08%,15岁及以上人群主要意外死因为机动车辆交通事故,25~59岁青壮年第2位意外死因为自杀,60岁以上人群第2位意外死因为意外跌落.结论 意外伤害已经成为五华县居民的主要死因之一,机动车辆交通事故、淹死、自杀是主要意外死因,应加大关注力度,全面落实伤害三级预防措施.%Objective To investigate the trend of accidental death in Wuhua county, in order to provide the scientific basis for formulate the corresponding prevention and control strategy. Methods Collecting and analyzing the accidental death deta of all populations death monitoring data in Wuhua county in 2006 to 2011 years. Results 2328 people were accidental death, the average mortality rate was 30. 18/10 , accounted for 6. 46% and ranked No. 5 of all causes of death. The accidental death rate of male and female were 39. 38/105 and 20. 43/ 105 respectively. The rate of male was higher than that of female. The top of accidental death causes were motor vehicle traffic accident, drowning, suicide, accidental drop and accidental poisoning. Except the zero age group, the accidental death ascended following growing age. Drowning was the first accidental death cause of the groups of age 0 to 4 and age 5 tol4 years old, with the composition ratio of 63. 58% and 57. 08

  4. ABERRANT PROMOTER METHYLATION OF MULTIPLE GENES IN SPUTUM FROM INDIVIDUALS EXPOSED TO SMOKY COAL EMISSIONS

    Science.gov (United States)

    Aberrant methylation in the promoter region of cancer-related genes leads to gene transcriptional inactivation and plays an integral role in lung tumorigenesis. Recent studies demonstrated that promoter methylation was detected not only in lung tumors from patients with lung canc...

  5. Performance on Tests of Central Auditory Processing by Individuals Exposed to High-Intensity Blasts

    Science.gov (United States)

    2012-07-01

    this research at the (former) WRAMC. Drs. Frank Musiek and Richard Wilson generously provided essential testing materials. Dr. David Lilly...wnl.0000230197.40410.db 18. Humes LE, Coughlin M, Talley L. Evaluation of the use of a new compact disc for auditory perceptual assessment in the

  6. Brain dynamics in spider-phobic individuals exposed to phobia-relevant and other emotional stimuli

    OpenAIRE

    Michalowski, Jaroslaw; Melzig, Christiane; Weike, Almut I.; Stockburger, Jessica; Schupp, Harald Thomas; Hamm, Alfons

    2009-01-01

    Dense sensor event-related brain potentials were measured in participants with spider phobia and nonfearful controls during viewing of phobia-relevant spider and standard emotional (pleasant, unpleasant, neutral) pictures. Irrespective of the picture content, spider phobia participants responded with larger P1 amplitudes than controls, suggesting increased vigilance in this group. Furthermore, spider phobia participants showed a significantly enlarged early posterior negativity (EPN) and late...

  7. Brain dynamics in spider-phobic individuals exposed to phobia-relevant and other emotional stimuli.

    Science.gov (United States)

    Michalowski, Jaroslaw M; Melzig, Christiane A; Weike, Almut I; Stockburger, Jessica; Schupp, Harald T; Hamm, Alfons O

    2009-06-01

    Dense sensor event-related brain potentials were measured in participants with spider phobia and nonfearful controls during viewing of phobia-relevant spider and standard emotional (pleasant, unpleasant, neutral) pictures. Irrespective of the picture content, spider phobia participants responded with larger P1 amplitudes than controls, suggesting increased vigilance in this group. Furthermore, spider phobia participants showed a significantly enlarged early posterior negativity (EPN) and late positive potential (LPP) during the encoding of phobia-relevant pictures compared to nonfearful controls. No group differences were observed for standard emotional materials indicating that these effects were specific to phobia-relevant material. Within group comparisons of the spider phobia group, though, revealed comparable EPN and LPP evoked by spider pictures and emotional (unpleasant and pleasant) picture contents. These results demonstrate a temporal unfolding in perceptual processing from unspecific vigilance (P1) to preferential responding (EPN and LPP) to phobia-relevant materials in the spider phobia group. However, at the level of early stimulus processing, these effects of increased attention seem to be related to emotional relevance of the stimulus cues rather than reflecting a fear-specific response.

  8. Carcinogenesis and Inflammatory Effects of Plutonium-Nitrate Retention in an Exposed Nuclear Worker and Beagle Dogs.

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, Christopher E. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Wang, Xihai [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Robinson, Robert J. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Brooks, Antone L. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Lovaglio, Jamie A. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Patton, Kristin M. [Battelle Toxicology Northwest, Richland, WA (United States); McComish, Stacey [United States Transuranium and Uranium Registries, Washington State University, College of Pharmacy, Richland, WA (United States); Tolmachev, Sergei Y. [United States Transuranium and Uranium Registries, Washington State University, College of Pharmacy, Richland, WA (United States); Morgan, William F. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

    2014-01-01

    The genetic and inflammatory response pathways elicited following plutonium exposure in archival lung tissue of an occupationally exposed human and experimentally exposed beagle dogs were investigated. These pathways include: tissue injury, apoptosis and gene expression modifications related to carcinogenesis and inflammation. In order to determine which pathways are involved, multiple lung samples from a plutonium exposed worker (Case 0269), a human control (Case 0385), and plutonium exposed beagle dogs were examined using histological staining and immunohistochemistry. Examinations were performed to identify target tissues at risk of radiation-induced fibrosis, inflammation, and carcinogenesis. Case 0269 showed interstitial fibrosis in peripheral and subpleural regions of the lung, but no pulmonary tumors. In contrast, the dogs with similar and higher doses showed pulmonary tumors primarily in brochiolo-alveolar, peripheral and subpleural alveolar regions. The TUNEL assay showed slight elevation of apoptosis in tracheal mucosa, tumor cells, and nuclear debris was present in the inflammatory regions of alveoli and lymph nodes of both the human and the dogs. The expression of apoptosis and a number of chemokine/cytokine genes was slightly but not significantly elevated in protein or gene levels compared to that of the control samples. In the beagles, mucous production was increased in the airway epithelial goblet cells and glands of trachea, and a number of chemokine/cytokine genes showed positive immunoreactivity. This analysis of archival tissue from an accidentally exposed worker and in a large animal model provides valuable information on the effects of long-term retention of plutonium in the respiratory tract and the histological evaluation study may impact mechanistic studies of radiation carcinogenesis.

  9. Error-related negativities during spelling judgments expose orthographic knowledge.

    Science.gov (United States)

    Harris, Lindsay N; Perfetti, Charles A; Rickles, Benjamin

    2014-02-01

    In two experiments, we demonstrate that error-related negativities (ERNs) recorded during spelling decisions can expose individual differences in lexical knowledge. The first experiment found that the ERN was elicited during spelling decisions and that its magnitude was correlated with independent measures of subjects' spelling knowledge. In the second experiment, we manipulated the phonology of misspelled stimuli and observed that ERN magnitudes were larger when misspelled words altered the phonology of their correctly spelled counterparts than when they preserved it. Thus, when an error is made in a decision about spelling, the brain processes indexed by the ERN reflect both phonological and orthographic input to the decision process. In both experiments, ERN effect sizes were correlated with assessments of lexical knowledge and reading, including offline spelling ability and spelling-mediated vocabulary knowledge. These results affirm the interdependent nature of orthographic, semantic, and phonological knowledge components while showing that spelling knowledge uniquely influences the ERN during spelling decisions. Finally, the study demonstrates the value of ERNs in exposing individual differences in lexical knowledge.

  10. Método para estimar el impacto económico de los accidentes de trabajo en los principales indicadores financieros

    OpenAIRE

    Vanegas Serna, Diego Alexander

    2014-01-01

    El interés de este trabajo es mostrar un método basado en instrumentos financieros que se aproxime a la cuantificación del impacto económico de los accidentes de trabajo en los principales indicadores financieros que frecuentemente la alta gerencia utiliza para el direccionamiento y evaluación de la salud económica de la organización -- Realizar la medición del impacto económico implica extraer las variables de los accidentes de trabajo que se pueden costear y que posiblemente puedan relacion...

  11. ACCIDENTES CON EXPOSICIÓN A MATERIAL BIOLÓGICO CONTAMINADO POR VIH EN TRABAJADORES DE UN HOSPITAL DE TERCER NIVEL DE MADRID (1986-2001)

    OpenAIRE

    2004-01-01

    Fundamento: La contaminación por el virus de la inmunodeficiencia humana (VIH) es un riesgo ocupacional para los profesionales sanitarios accidentados contaminados con sangre positiva al VIH. El objetivo de nuestro estudio es describir las características de los accidentes registrados durante dieciséis años en un hospital general con sangre o fluidos biológicos procedentes de pacientes VIH positivos, determinar las tasas de exposición accidental en las diferentes categorí...

  12. Modelo de predicción de ocurrencia de accidentes en tramos de carretera mediante la medición continúa de variables de influencia

    OpenAIRE

    2000-01-01

    El fenómeno accidente de tráfico constituye un hecho de notable significación, especialmente debido a las consecuencias negativas que provoca para personas, vehículos e instalaciones. En las últimas décadas, a pesar de la mejora de las condiciones de seguridad de las carreteras, se ha producido un aumento notable del número de accidentes, debido en gran parte al incremento del parque automovilístico y de la movilidad de la población. Ante esta evidencia, sigue vigente la necesidad de un i...

  13. The neurobiology of individuality

    Science.gov (United States)

    de Bivort, Benjamin

    2015-03-01

    Individuals often display conspicuously different patterns of behavior, even when they are very closely related genetically. These differences give rise to our sense of individuality, but what is their molecular and neurobiological basis? Individuals that are nominally genetically identical differ at various molecular and neurobiological levels: cell-to-cell variation in somatic genomes, cell-to-cell variation in expression patterns, individual-to-individual variation in neuronal morphology and physiology, and individual-to-individual variation in patterns of brain activity. It is unknown which of these levels is fundamentally causal of behavioral differences. To investigate this problem, we use the fruit fly Drosophila melanogaster, whose genetic toolkit allows the manipulation of each of these mechanistic levels, and whose rapid lifecycle and small size allows for high-throughput automation of behavioral assays. This latter point is crucial; identifying inter-individual behavioral differences requires high sample sizes both within and across individual animals. Automated behavioral characterization is at the heart of our research strategy. In every behavior examined, individual flies have individual behavioral preferences, and we have begun to identify both neural genes and circuits that control the degree of behavioral variability between individuals.

  14. On Tour with the "Accidental" Expert: Ethical Dilemmas of the Development Consultant.

    Science.gov (United States)

    Basile, Michael L.

    This paper explores Max Weber's study of the origins of the secularization of the Puritan work ethic and examines the hybridized category of secular science expert. The hybrid construct provides an opening for the critical analysis of the concrete activity of development from two perspectives, the structural and the individual. The individual…

  15. Towards Musical Individuation

    Directory of Open Access Journals (Sweden)

    Dong Min Kim

    2008-03-01

    Full Text Available In Jungian theory, heavily influenced by Zen Buddhism, the developmental stages of human life are symbolized as a circle that represents the wholeness, and the open ended process towards the wholeness is called Individuation. Within the circle there are two stages; the Morning and the Afternoon of Life, and the latter begins at the age of 35, an age at which individuation begins and one that I have reached and passed. Thus, it seemed to be a perfect time for me to begin my own journey towards individuation, especially musical individuation since music had always been such a central part of my life. The first step of individuation is to be aware of one’s individual, social, cultural unconscious forces that affect conscious thoughts and behavior. Thus, my musical individuation began with my attempts to be aware of the unconscious forces beneath my conscious thoughts and behaviors.

  16. Individually Controlled Indoor Environment

    DEFF Research Database (Denmark)

    Melikov, Arsen Krikor

    2004-01-01

    The thermal environment and inhaled air quality in buildings to which occupants are exposed has an effect on their health, comfort, performance and productivity. Heating, ventilating and air-conditioning (HVAC) of buildings today is designed to provide a uniform environment. However, large...

  17. Performance characterization of geopolymer composites for hot sodium exposed sacrificial layer in fast breeder reactors

    Energy Technology Data Exchange (ETDEWEB)

    Haneefa, K. Mohammed, E-mail: mhkolakkadan@gmail.com [Department of Civil Engineering, IIT Madras, Chennai (India); Santhanam, Manu [Department of Civil Engineering, IIT Madras, Chennai (India); Parida, F.C. [Radiological Safety Division, Indira Gandhi Centre for Atomic Research, Kalpakkam (India)

    2013-12-15

    Highlights: • Performance evaluation of geopolymers subjected to hot liquid sodium is performed. • Apart from mechanical properties, micro-analytical techniques are used for material characterization. • The geopolymer composite showed comparatively lesser damage than conventional cement composites. • Geopolymer technology can emerge as a new choice for sacrificial layer in SCFBRs. - Abstract: A sacrificial layer of concrete is used in sodium cooled fast breeder reactors (SCFBRs) to mitigate thermo-chemical effect of accidentally spilled sodium at and above 550 °C on structural concrete. Performance of this layer is governed by thermo-chemical stability of the ingredients of sacrificial layer concrete. Concrete with limestone aggregate is generally used as a sacrificial layer. Conventional cement based systems exhibit instability in hot liquid sodium environment. Geo-polymer composites are well known to perform excellently at elevated temperatures compared to conventional cement systems. This paper discusses performance of such composites subjected to exposure of hot liquid sodium in air. The investigation includes comprehensive evaluation of various geo-polymer composites before any exposure, after heating to 550 °C in air, and after immersing in hot liquid sodium initially heated to 550 °C in air. Results from the current study indicate that hot liquid sodium produces less damage to geopolymer composites than to the existing conventional cement based system. Hence, the geopolymer technology has potential application in mitigating the degrading effects of sodium fires and can emerge as a new choice for sodium exposed sacrificial layer in SCFBRs.

  18. O HIV e o trabalhador de enfermagem frente ao acidente com material perfurocortante El VIH y el trabajador de enfermería frente a accidentes con material punzocortante HIV and the nursing professional in face of needlestick accidents

    Directory of Open Access Journals (Sweden)

    Mariana Vieira

    2008-12-01

    Full Text Available O estudo tem como objetivo identificar a produção científica sobre o acidente de trabalho do profissional de enfermagem com material biológico contaminado por HIV e caracterizar os fatores predisponentes aos acidentes de trabalho, assim como os procedimentos realizados pós-exposição ao material perfurocortante potencialmente contaminado pelo HIV. É uma revisão de literatura, cuja busca bibliográfica por palavras-chave foi realizada por meio da base de dados LILACS a partir de 2000. Constatou-se que os fatores predisponentes à ocorrência dos acidentes de trabalho com perfurocortantes estão relacionados tanto às condições de trabalho, como as condições individuais. Frente a estes acidentes, os trabalhadores de enfermagem têm necessidade de conhecer as condutas pós-exposição ao material perfurocortante potencialmente contaminado pelo HIV. Concluímos que a adoção das precauções-padrão no trabalho em saúde é condição fundamental para a segurança dos trabalhadores, independente da área de atuação, pois o número de casos de HIV é crescente.El estudio tiene como objetivo identificar la producción científica sobre accidentes de trabajo de profesionales de enfermería con material biológico contaminado por VIH y determinar las características de los factores que los favorecen, así como los procedimientos realizados posteriores al accidente con material punzocortante potencialmente contaminado por VIH. Revisión bibliográfica a través de palabras claves en la base de datos LILACS a partir del año 2000. Se constató que los factores que predisponen estos accidentes de trabajo se relacionan tanto con las condiciones de trabajo como con las condiciones individuales. Es necesario que los trabajadores de salud conozcan las conductas en casos de accidente punzocortante por VIH. Concluimos que la adopción de medidas patrón es una condición fundamental para la seguridad de los trabajadores, independientemente del

  19. Symmetric Tamm-Dancoff q-oscillator: representation, quasi-Fibonacci nature, accidental degeneracy and coherent states

    CERN Document Server

    Chung, Won Sang; Kachurik, I I; Rebesh, A P

    2014-01-01

    In this paper we propose a symmetric q-deformed Tamm-Dancoff (S-TD) oscillator algebra and study its representation, coordinate realization, and main properties. In particular, the non-Fibonacci (more exactly, quasi-Fibonacci) nature of S-TD oscillator is established, the possibility of relating it to certain p,q-deformed oscillator family shown, the occurrence of the pairwise accidental degeneracy proven. We also find the coherent state for the S-TD oscillator and show that it satisfies completeness relation. Main advantage of the S-TD model over usual Tamm-Dancoff oscillator is that due to (qq^{-1})-symmetry it admits not only real, but also complex (phase-like) values of the deformation parameter q.

  20. Poverty and fatal accidental drug overdoses of cocaine and opiates in New York City: an ecological study.

    Science.gov (United States)

    Marzuk, P M; Tardiff, K; Leon, A C; Hirsch, C S; Stajic, M; Portera, L; Hartwell, N

    1997-05-01

    This ecological study examines the association of the poverty status of urban communities in New York City with their mortality rates of accidental drug overdoses. Mean annual age-adjusted rates of drug overdoses involving cocaine, opiates, or both (n = 1,684) were calculated for each of 59 residential community districts in New York City for 1990-1992. A linear regression analysis was performed to test the association of the mortality rate with the poverty status of the district as measured by the proportion of the district living below the 1989 U.S. poverty line. Poverty status accounted for 69% of the variance in the drug overdose mortality rates of communities (p poverty status of communities in New York City.