The business of refractive laser assisted cataract surgery (ReLACS).

Science.gov (United States)

Berdahl, John P; Jensen, Matthew P

2014-01-01

Refractive Laser Assisted Cataract Surgery (ReLACS) combines the femtosecond laser with other noncovered tests and services in an attempt to reduce spectacle dependence in combination with cataract surgery. Significant interest is present among ophthalmologists who are considering adopting this technology, however significant capital outlays and continuing expenses can make the decision to adopt ReLACS foreboding. We review the financial considerations of ReLACS and review the trends seen in early adopters of this technology. Recent findings have shown that ReLACS is a growing segment of cataract surgery. Most practices who have implemented the technology have broken even and have a positive outlook on the financial return of implementing the ReLACS program. The average break-even analysis point for practices is around 230 cases a year. ReLACS is growing and appears to be a financial viable approach for many practices.

Adsorption Properties of Lac Dyes on Wool, Silk, and Nylon

Directory of Open Access Journals (Sweden)

Bo Wei

2013-01-01

Full Text Available There has been growing interest in the dyeing of textiles with natural dyes. The research about the adsorption properties of natural dyes can help to understand their adsorption mechanism and to control their dyeing process. This study is concerned with the kinetics and isotherms of adsorption of lac dyes on wool, silk, and nylon fibers. It was found that the adsorption kinetics of lac dyes on the three fibers followed the pseudosecond-order kinetic model, and the adsorption rate of lac dyes was the fastest for silk and the slowest for wool. The activation energies for the adsorption process on wool, silk, and nylon were found to be 107.15, 87.85, and 45.31 kJ/mol, respectively. The adsorption of lac dyes on the three fibers followed the Langmuir mechanism, indicating that the electrostatic interactions between lac dyes and those fibers occurred. The saturation values for lac adsorption on the three fibers decreased in the order of wool > silk > nylon; the Langmuir affinity constant of lac adsorption on nylon was much higher than those on wool and silk.

lac repressor is an antivirulence factor of Salmonella enterica: its role in the evolution of virulence in Salmonella.

Directory of Open Access Journals (Sweden)

Sandeepa M Eswarappa

Full Text Available The genus Salmonella includes many pathogens of great medical and veterinary importance. Bacteria belonging to this genus are very closely related to those belonging to the genus Escherichia. lacZYA operon and lacI are present in Escherichia coli, but not in Salmonella enterica. It has been proposed that Salmonella has lost lacZYA operon and lacI during evolution. In this study, we have investigated the physiological and evolutionary significance of the absence of lacI in Salmonella enterica. Using murine model of typhoid fever, we show that the expression of LacI causes a remarkable reduction in the virulence of Salmonella enterica. LacI also suppresses the ability of Salmonella enterica to proliferate inside murine macrophages. Microarray analysis revealed that LacI interferes with the expression of virulence genes of Salmonella pathogenicity island 2. This effect was confirmed by RT-PCR and Western blot analysis. Interestingly, we found that SBG0326 of Salmonella bongori is homologous to lacI of Escherichia coli. Salmonella bongori is the only other species of the genus Salmonella and it lacks the virulence genes of Salmonella pathogenicity island 2. Overall, our results demonstrate that LacI is an antivirulence factor of Salmonella enterica and suggest that absence of lacI has facilitated the acquisition of virulence genes of Salmonella pathogenicity island 2 in Salmonella enterica making it a successful systemic pathogen.

Intelligent Local Avoided Collision (iLAC) MAC Protocol for Very High Speed Wireless Network

Science.gov (United States)

Hieu, Dinh Chi; Masuda, Akeo; Rabarijaona, Verotiana Hanitriniala; Shimamoto, Shigeru

Future wireless communication systems aim at very high data rates. As the medium access control (MAC) protocol plays the central role in determining the overall performance of the wireless system, designing a suitable MAC protocol is critical to fully exploit the benefit of high speed transmission that the physical layer (PHY) offers. In the latest 802.11n standard [2], the problem of long overhead has been addressed adequately but the issue of excessive colliding transmissions, especially in congested situation, remains untouched. The procedure of setting the backoff value is the heart of the 802.11 distributed coordination function (DCF) to avoid collision in which each station makes its own decision on how to avoid collision in the next transmission. However, collision avoidance is a problem that can not be solved by a single station. In this paper, we introduce a new MAC protocol called Intelligent Local Avoided Collision (iLAC) that redefines individual rationality in choosing the backoff counter value to avoid a colliding transmission. The distinguishing feature of iLAC is that it fundamentally changes this decision making process from collision avoidance to collaborative collision prevention. As a result, stations can avoid colliding transmissions with much greater precision. Analytical solution confirms the validity of this proposal and simulation results show that the proposed algorithm outperforms the conventional algorithms by a large margin.

Broad band energy distribution of UV-bright BL Lac objects

International Nuclear Information System (INIS)

Maraschi, L.; Tanzi, E.G.; Treves, A.

1984-01-01

IUE satellite data in the 1200-2000 and 1900-3200 A intervals of BL Lac objects are analyzed in terms of two discernible groups. A total of 25 BL Lac objects were observed, with differences between groups displayed in terms of the power slope of the energy of the UV emissions, i.e., slopes of 1 and 2. Comparisons of the spectra with those of quasars showed that quasars have a small spectral index in the 1000-6000 A band and no correlation exists between the spectral index and UV flux of the BL Lac objects. The comparisons underscore the lack of a thermal component for BL Lac objects. Steep spectral components in both BL Lac objects and highly polarized quasars emissions could both be due to synchrotron emission. Compton scattering of relativistic electrons off synchrotron photons could produce the X ray emissions. 44 references

Broad band energy distribution of UV-bright BL Lac objects

Energy Technology Data Exchange (ETDEWEB)

Maraschi, L.; Tanzi, E.G.; Treves, A.

1984-01-01

IUE satellite data in the 1200-2000 and 1900-3200 A intervals of BL Lac objects are analyzed in terms of two discernible groups. A total of 25 BL Lac objects were observed, with differences between groups displayed in terms of the power slope of the energy of the UV emissions, i.e., slopes of 1 and 2. Comparisons of the spectra with those of quasars showed that quasars have a small spectral index in the 1000-6000 A band and no correlation exists between the spectral index and UV flux of the BL Lac objects. The comparisons underscore the lack of a thermal component for BL Lac objects. Steep spectral components in both BL Lac objects and highly polarized quasars emissions could both be due to synchrotron emission. Compton scattering of relativistic electrons off synchrotron photons could produce the X ray emissions. 44 references.

Infrared polarimetry and photometry of BL Lac objects. 3

Energy Technology Data Exchange (ETDEWEB)

Holmes, P A; Brand, P W.J.L. [Edinburgh Univ. (UK). Dept. of Astronomy; Impey, C D [Hawaii Univ., Honolulu (USA). Inst. for Astronomy; Williams, P M [UKIRT, Hilo, HI (USA)

1984-10-15

The data presented here is part of a continuing monitoring programme of BL lac objects with J, H and K photometry and polarimetry. A total of 30 BL Lac objects have now been observed photometrically. Infrared polarimetry has also been obtained for 24 of these objects. The sample is sufficiently large to examine statistically, and several important correlations have emerged. Internight variations and wavelength dependence of polarization indicate that BL Lac objects, as a class, may be understood in terms of a relatively simple two-component model.

The comparison between LAC and ALA

Directory of Open Access Journals (Sweden)

Tzu-heng Chiu

2000-12-01

Full Text Available A good library association serves its members, improves the librarianship, and helps library institutions achieving their missions. This article describes the history, missions and goals, organization structure, membership, financial sources, professional activities, publication, and website of the Library Association of China (LAC and American Library Association (ALA, respectively. Considering social / cultural / political differences between Taiwan and the United Sates, the author then compares these two library associations from the eight factors mentioned above. At the end, suggestions for the LAC are proposed.[Article content in Chinese

Clustering environments of BL Lac objects

Science.gov (United States)

Wurtz, Ronald; Ellingson, Erica; Stocke, John T.; Yee, H. K. C.

1993-01-01

We report measurements of the amplitude of the BL Lac galaxy spatial covariance function, B(gb), for the fields of five BL Lacertae objects. We present evidence for rich clusters around MS 1207+39 and MS 1407+59, and confirm high richness for the cluster containing H0414+009. We discuss the ease of 3C 66 A and find evidence for a poor cluster based on an uncertain redshift of z = 0.444. These data suggest that at least some BL Lac objects are consistent with being FR 1 radio galaxies in rich clusters.

Louisiana SIP: LAC 33:III Ch. 7 - Table 2 - Ambient Air--Methods of Contaminant Measurements; SIP effective 1989-05-08 (LAc49) and 1989-08-14 (LAc50) to 2011-08-03 (LAd34 - Moved to Section 711 and revised [adds PM-2.5])

Science.gov (United States)

Louisiana SIP: LAC 33:III Ch. 7 - Table 2 - Ambient Air--Methods of Contaminant Measurements; SIP effective 1989-05-08 (LAc49) and 1989-08-14 (LAc50) to 2011-08-03 (LAd34 - Moved to Section 711 and revised [adds PM-2.5])

Gene-mutation assays in lambda-lacZ transgenic mice : comparison of lacZ with endogenous genes in splenocytes and small intestinal epithelium

NARCIS (Netherlands)

Delft, J.H.M. van; Bergmans, A.; Dam, F.J. van; Tates, A.D.; Howard, L.; Winton, D.J.; Baan, R.A.

1998-01-01

Comparison of results derived from transgenic animal gene-mutation assays with those from mutation analyses in endogenous genes is an important step in the validation of the former. We have used λlacZ transgenic mice to study alkylation-induced mutagenesis in vivo in (a) lacZ and hprt in spleen

Induction of the lac carrier and an associated membrane protein in Escherichia coli

International Nuclear Information System (INIS)

Lagarias, D.M.

1985-01-01

Induction of the lac operon in wild type Escherichia coli strains results in synthesis of a 16 kilodalton inner membrane protein in addition to the known products of the lacZ, lacY and lacA genes. Cells carrying the lacY gene on a plasmid over produce this 16 kilodalton polypeptide as well as the Lac carrier, the membrane protein product of the lacY gene. However, [ 35 S]methionine labeling of minicells carrying the lacY plasmid shows that the 16 kDa protein is not synthesized from the plasmid DNA. The 16 kDa protein was purified and partially characterized. It is an acidic membrane protein of apparent molecular weight 15,800 whose amino terminal sequence (NH 2 -Met-Arg-Asn-Phe-Asp-Leu-) does not correspond to any nucleotide sequence known in lac operon DNA. Using antibody prepared to the purified 16 kDa protein, a quantitative analysis of conditions under which this protein is made was accomplished, and reveals that the amount of 16 kDa protein which appears in the membrane is proportional to lac operon expression. Hybridization of a synthetic oligonucleotide probe complementary to the 5' end of 16 kDa protein mRNA shows that its synthesis is regulated at the level of transcription. A description of attempts to clone this gene is given. Possible functional roles for the 16 kDa protein are discussed

Opening Up Natural Resource Based Industries for Innovation (LAC ...

International Development Research Centre (IDRC) Digital Library (Canada)

Opening Up Natural Resource Based Industries for Innovation (LAC). Commodities based on natural resources account for at least half of the exports of two-thirds of the countries in Latin America and the Caribbean (LAC). There is growing concern, however, that existing natural resource-based industries are ...

Evidence for an intermediate conformational state of LacY.

Science.gov (United States)

Jiang, Xiaoxu; Guan, Lan; Zhou, Yonggang; Hong, Wen-Xu; Zhang, Qinghai; Kaback, H Ronald

2012-03-20

LacY mutant Cys154 → Gly exhibits a periplasmic-closed crystal structure identical to the WT, but is periplasmic-open in the membrane. The mutant hardly catalyzes transport, but binds galactosides from either side of the membrane with the same affinity and is resistant to site-directed proteolysis relative to the pseudo-WT. Site-directed alkylation was also applied to 11 single-Cys mutants in Cys154 → Gly LacY in right-side-out membrane vesicles or after solubilization and purification in dodecyl-β-D-maltopyranoside (DDM). Unlike the pseudo-WT, Cys replacements on the periplasmic side of the Cys154 → Gly mutant label rapidly in the membrane without sugar, but labeling decreases markedly after the mutant proteins are purified. Thus, Cys154 → Gly LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. Notably, branched-chain or neopentyl glycol maltoside detergents stabilize Cys154 → Gly LacY in the membrane-embedded form.

The use of lac-type promoters in control analysis

DEFF Research Database (Denmark)

Jensen, Peter Ruhdal; Westerhoff, H. v.; Michelsen, Ole

1993-01-01

experimentally by constructing E. coli strains, in which the chromosomal atp operon is transcribed from the lacUV5 and the tacI promoter. We measured the concentration of the c subunit of H+-ATPase, and found that the expression of this enzyme could be modulated between non-detectable levels and up to five times...... the wild-type level. Thus, in the absence of inducer, no expression of atp genes could be detected when the atp operon was controlled by the lacUV5 promoter, and we estimate that the expression was less than 0.0025 times the wild-type level. We show that the introduction of a lac Y mutation facilitated...

Physico-Mechanical Properties of Coprocessed Excipient MicroceLac® 100 by DM(3) Approach.

Science.gov (United States)

Haware, Rahul V; Kancharla, Joseph P; Udupa, Aishwarya K; Staton, Scott; Gupta, Mali R; Al-Achi, Antoine; Stagner, William C

2015-11-01

To determine the effect of relative humidity (RH) and hydroxypropyl methylcellulose (HPMC) on the physico-mechanical properties of coprocessed MacroceLac(®) 100 using 'DM(3)' approach. Effects of RH and 5% w/w HPMC on MacroceLac(®) 100 Compressibility Index (CI) and tablet mechanical strength (TMS) were evaluated by 'DM(3)'. The 'DM(3)' approach evaluates material properties by combining 'design of experiments', material's 'macroscopic' properties, 'molecular' properties, and 'multivariate analysis' tools. A 4X4 full-factorial experimental design was used to study the relationship of MacroceLac(®) 100 molecular properties (moisture content, dehydration, crystallization, fusion enthalpy, and moisture uptake) and macroscopic particle size and shape on CI and TMS. A physical binary mixture (PBM) of similar composition to MacroceLac(®) 100 was also evaluated. Multivariate analysis of variance (MANOVA), principle component analysis, and partial least squares (PLS) were used to analyze the data. MANOVA CI ranking was: PBM-HPMC > PBM > MicroceLac(®)100 > MicroceLac(®)100-HPMC (p TMS values were lower than MicroceLac(®)100 and MicroceLac(®)100-HPMC (p TMS. Significant MicroceLac(®)100 changes occurred with % RH exposure affecting performance attributes. HPMC physical addition did not prevent molecular or macroscopic matrix changes.

High-level expression of Bacillus naganoensis pullulanase from recombinant Escherichia coli with auto-induction: effect of lac operator.

Directory of Open Access Journals (Sweden)

Yao Nie

Full Text Available Pullulanase plays an important role in specific hydrolysis of branch points in amylopectin and is generally employed as an important enzyme in starch-processing industry. So far, however, the production level of pullulanase is still somewhat low from wide-type strains and even heterologous expression systems. Here the gene encoding Bacillus naganoensis pullulanase was amplified and cloned. For expression of the protein, two recombinant systems, Escherichia coli BL21(DE3/pET-20b(+-pul and E. coli BL21(DE3/pET-22b(+-pul, were constructed, both bearing T7 promoter and signal peptide sequence, but different in the existance of lac operator and lacI gene encoding lac repressor. Recombinant pullulanase was initially expressed with the activity of up to 14 U/mL by E. coli BL21(DE3/pET-20b(+-pul with IPTG induction in LB medium, but its expression level reduced continually with the extension of cryopreservation time and basal expression was observed. However, E. coli BL21(DE3/pET-22b(+-pul , involving lac operator downstream of T7 promoter to regulate foreign gene transcription, exhibited pullulanase activity consistently without detected basal expression. By investigating the effect of lac operator, basal expression of foreign protein was found to cause expression instability and negative effect on production of target protein. Thus double-repression strategy was proposed that lac operators in both chromosome and plasmid were bound with lac repressor to repress T7 RNA polymerase synthesis and target protein expression before induction. Consequently, the total activity of pullulanase was remarkably increased to 580 U/mL with auto-induction by lac operator-involved E. coli BL21(DE3/pET-22b(+-pul. When adding 0.6% glycine in culture, the extracellular production of pullulanase was significantly improved with the extracellular activity of 502 U/mL, which is a relatively higher level achieved to date for extracellular production of pullulanase. The

Infrared polarimetry and photometry of BL Lac objects

Energy Technology Data Exchange (ETDEWEB)

Impey, C D; Brand, P W.J.L. [Edinburgh Univ. (UK); Wolstencroft, R D; Williams, P M [Royal Observatory, Edinburgh (UK)

1982-07-01

Infrared polarimetry and photometry have been obtained for a sample of 18 BL Lac objects. The data covers a period of one year and is part of a continuing monitoring programme; all observations were in the J,H and K wavebands. Large and variable degrees of polarization are a common property of the sample. Two BL Lac objects show wavelength-dependent polarization, with the polarization increasing towards shorter wavelengths, and two objects show evidence for position angle rotations over a five-day period. The relationship between changes in polarized and total flux is also discussed. The BL Lac objects cover an enormous range of infrared luminosity; the three most luminous having Lsub(IR) > 10/sup 46/ erg s/sup -1/ and the other end of the range having infrared luminosities similar to normal elliptical galaxies. These are the first published infrared polarimetric observations for eight of the sample.

Beware of your Cre-Ation: lacZ expression impairs neuronal integrity and hippocampus-dependent memory.

Science.gov (United States)

Reichel, J M; Bedenk, B T; Gassen, N C; Hafner, K; Bura, S A; Almeida-Correa, S; Genewsky, A; Dedic, N; Giesert, F; Agarwal, A; Nave, K-A; Rein, T; Czisch, M; Deussing, J M; Wotjak, C T

2016-10-01

Expression of the lacZ-sequence is a widely used reporter-tool to assess the transgenic and/or transfection efficacy of a target gene in mice. Once activated, lacZ is permanently expressed. However, protein accumulation is one of the hallmarks of neurodegenerative diseases. Furthermore, the protein product of the bacterial lacZ gene is ß-galactosidase, an analog to the mammalian senescence-associated ß-galactosidase, a molecular marker for aging. Therefore we studied the behavioral, structural and molecular consequences of lacZ expression in distinct neuronal sub-populations. lacZ expression in cortical glutamatergic neurons resulted in severe impairments in hippocampus-dependent memory accompanied by marked structural alterations throughout the CNS. In contrast, GFP expression or the expression of the ChR2/YFP fusion product in the same cell populations did not result in either cognitive or structural deficits. GABAergic lacZ expression caused significantly decreased hyper-arousal and mild cognitive deficits. Attenuated structural and behavioral consequences of lacZ expression could also be induced in adulthood, and lacZ transfection in neuronal cell cultures significantly decreased their viability. Our findings provide a strong caveat against the use of lacZ reporter mice for phenotyping studies and point to a particular sensitivity of the hippocampus formation to detrimental consequences of lacZ expression. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Optical Spectra Evolution of BL Lac Objects XW Bi1,∗ , BZ Wang2

Indian Academy of Sciences (India)

low-frequency peaked BL Lac objects (LBLs) is steeper than the high- frequency peaked BL Lac ... vision of BL Lac objects. Many investigators .... We are grateful to the Scientific Research Foundation of the Education Department of Yunnan ...

Flat radio-spectrum galaxies and BL Lacs I. Core properties

NARCIS (Netherlands)

Dennett-Thorpe, J; Marcha, MJ

This paper concerns the relationship of BL Lacs and flat-spectrum weak emission-line galaxies. We compare the weak emission-line galaxies and the BL Lacs in a sample of 57 flat-spectrum objects (Marcha et al. 1996), using high-frequency radio and non-thermal optical flux densities, spectral indices

Lysines 72, 80 and 213 and aspartic acid 210 of the Lactococcus lactis LacR repressor are involved in the response to the inducer tagatose-6-phosphate leading to induction of lac operon expression.

Science.gov (United States)

van Rooijen, R J; Dechering, K J; Niek, C; Wilmink, J; de Vos, W M

1993-02-01

Site-directed mutagenesis of the Lactococcus lactis lacR gene was performed to identify residues in the LacR repressor that are involved in the induction of lacABCDFEGX operon expression by tagatose-6-phosphate. A putative inducer binding domain located near the C-terminus was previously postulated based on homology studies with the Escherichia coli DeoR family of repressors, which all have a phosphorylated sugar as inducer. Residues within this domain and lysine residues that are charge conserved in the DeoR family were changed into alanine or arginine. The production of the LacR mutants K72A, K80A, K80R, D210A, K213A and K213R in the LacR-deficient L.lactis strain NZ3015 resulted in repressed phospho-beta-galactosidase (LacG) activities and decreased growth rates on lactose. Gel mobility shift assays showed that the complex between a DNA fragment carrying the lac operators and LacR mutants K72A, K80A, K213A and D210A did not dissociate in the presence of tagatose-6-phosphate, in contrast to wild type LacR. Other mutations (K62A/K63A, K72R, K73A, K73R, T212A, F214R, R216R and R216K) exhibited no gross effects on inducer response. The results strongly suggest that the lysines at positions 72, 80 and 213 and aspartic acid at position 210 are involved in the induction of lac operon expression by tagatose-6-phosphate.

The effect of stochasticity on the lac operon: an evolutionary perspective.

Directory of Open Access Journals (Sweden)

Milan van Hoek

2007-06-01

Full Text Available The role of stochasticity on gene expression is widely discussed. Both potential advantages and disadvantages have been revealed. In some systems, noise in gene expression has been quantified, in among others the lac operon of Escherichia coli. Whether stochastic gene expression in this system is detrimental or beneficial for the cells is, however, still unclear. We are interested in the effects of stochasticity from an evolutionary point of view. We study this question in the lac operon, taking a computational approach: using a detailed, quantitative, spatial model, we evolve through a mutation-selection process the shape of the promoter function and therewith the effective amount of stochasticity. We find that noise values for lactose, the natural inducer, are much lower than for artificial, nonmetabolizable inducers, because these artificial inducers experience a stronger positive feedback. In the evolved promoter functions, noise due to stochasticity in gene expression, when induced by lactose, only plays a very minor role in short-term physiological adaptation, because other sources of population heterogeneity dominate. Finally, promoter functions evolved in the stochastic model evolve to higher repressed transcription rates than those evolved in a deterministic version of the model. This causes these promoter functions to experience less stochasticity in gene expression. We show that a high repression rate and hence high stochasticity increases the delay in lactose uptake in a variable environment. We conclude that the lac operon evolved such that the impact of stochastic gene expression is minor in its natural environment, but happens to respond with much stronger stochasticity when confronted with artificial inducers. In this particular system, we have shown that stochasticity is detrimental. Moreover, we demonstrate that in silico evolution in a quantitative model, by mutating the parameters of interest, is a promising way to unravel

Baseline surveys of Lac Bay benthic and fish communities, Bonaire

NARCIS (Netherlands)

Debrot, A.O.; Hylkema, A.; Vogelaar, W.; Meesters, H.W.G.; Engel, M.S.; Leon, R.; Prud'homme van Reine, W.F.; Nagelkerken, I.

2012-01-01

Lac Bay is a clear-water, 5 m deep shallow tropical lagoon of 7 km2 opening onto the wave and wind exposed east coast of the island of Bonaire, southern Caribbean. Over the last decades land reclamation by mangroves in Lac has been expanding the surface of turbid, saline backwaters into the bay at

The REX survey as a Tool to Test the Beaming Model for BL Lacs

Science.gov (United States)

Caccianiga, A.; della Ceca, R.; Gioia, I. M.; Maccacaro, T.; Wolter, A.

We present the preliminary properties of the BL Lacs discovered in the REX survey (Caccianiga et al. 1998). In particular, we discuss a few sources with optical spectral properties ``intermediate'' between those of BL Lacs and those of elliptical galaxies. These objects could harbour weak (in the optical band) sources of non-thermal continuum in their nuclei and, if confirmed, they could represent the faint tail of the BL Lac population. The existence of such ``weak'' BL Lacs is matter of discussion in recent literature (e.g. Marcha et al. 1996) and could lead to a revision of the defining criteria of a BL Lac and, consequently, of their cosmological and statistical properties.

The Radio-optical Spectra of BL Lacs and Possible Relatives

Science.gov (United States)

Dennett-Thorpe, J.

I consider the suggestion that, in a complete sample of flat-spectrum radio sources with available optical spectra (Marcha et al 1996), the strong emission line objects, or those with passive elliptical spectra are close relatives of the BL Lacs. New observations at four frequencies from 8 to 43GHz are presented, together with evidence for radio variability. Combined with other radio and optical data from the literature, we are able to construct the non-thermal SEDs and use these to address the questions: are the optically passive objects potentially `unrecognised' BL Lacs (either intrinsically weak and/or hidden by starlight)? What is the relationship between the surprising number of strong emission-line objects and the BL Lacs?

Purified reconstituted lac carrier protein from Escherichia coli is fully functional.

Science.gov (United States)

Viitanen, P; Garcia, M L; Kaback, H R

1984-03-01

Proteoliposomes reconstituted with lac carrier protein purified from the plasma membrane of Escherichia coli catalyze each of the translocation reactions typical of the beta-galactoside transport system (i.e., active transport, counterflow, facilitated influx and efflux) with turnover numbers and apparent Km values comparable to those observed in right-side-out membrane vesicles. Furthermore, detailed kinetic studies show that the reconstituted system exhibits properties analogous to those observed in membrane vesicles. Imposition of a membrane potential (delta psi, interior negative) causes a marked decrease in apparent Km (by a factor of 7 to 10) with a smaller increase in Vmax (approximately equal to 3-fold). At submaximal values of delta psi, the reconstituted carrier exhibits biphasic kinetics, with one component manifesting the kinetic parameters of active transport and the other exhibiting the characteristics of facilitated diffusion. Finally, at low lactose concentrations, the initial velocity of influx varies linearly with the square of the proton electro-chemical gradient. The results provide quantitative support for the contention that a single polypeptide species, the product of the lac y gene, is responsible for each of the transport reactions typical of the beta-galactoside transport system.

RADIO-WEAK BL LAC OBJECTS IN THE FERMI ERA

Energy Technology Data Exchange (ETDEWEB)

Massaro, F.; Marchesini, E. J. [Dipartimento di Fisica, Università degli Studi di Torino (UniTO), via Pietro Giuria 1, I-10125 Torino (Italy); D’Abrusco, R.; Smith, Howard A. [Smithsonian Astrophysical Observatory, 60 Garden Street, 02138 Cambridge, MA (United States); Masetti, N. [INAF—Istituto di Astrofisica Spaziale e Fisica Cosmica di Bologna, via Gobetti 101, I-40129, Bologna (Italy); Andruchow, I. [Facultad de Ciencias Astronómicas y Geofísicas, Universidad Nacional de La Plata, Paseo del Bosque, B1900FWA, La Plata (Argentina)

2017-01-10

The existence of “radio-weak BL Lac objects” (RWBLs) has been an open question, and has remained unsolved since the discovery that quasars could be radio-quiet or radio-loud. Recently, several groups identified RWBL candidates, mostly found while searching for low-energy counterparts of the unidentified or unassociated gamma-ray sources listed in the Fermi catalogs. Confirming RWBLs is a challenging task since they could be confused with white dwarfs (WDs) or weak emission line quasars (WELQs) when there are not sufficient data to precisely draw their broadband spectral energy distribution, and their classification is mainly based on a featureless optical spectra. Motivated by the recent discovery that Fermi BL Lacs appear to have very peculiar mid-IR emission, we show that it is possible to distinguish between WDs, WELQs, and BL Lacs using the [3.4]–[4.6]–[12] μ m color–color plot built using the WISE magnitudes when the optical spectrum is available. On the basis of this analysis, we identify WISE J064459.38+603131 and WISE J141046.00+740511.2 as the first two genuine RWBLs, both potentially associated with Fermi sources. Finally, to strengthen our identification of these objects as true RWBLs, we present multifrequency observations for these two candidates to show that their spectral behavior is indeed consistent with that of the BL Lac population.

RADIO-WEAK BL LAC OBJECTS IN THE FERMI ERA

International Nuclear Information System (INIS)

Massaro, F.; Marchesini, E. J.; D’Abrusco, R.; Smith, Howard A.; Masetti, N.; Andruchow, I.

2017-01-01

The existence of “radio-weak BL Lac objects” (RWBLs) has been an open question, and has remained unsolved since the discovery that quasars could be radio-quiet or radio-loud. Recently, several groups identified RWBL candidates, mostly found while searching for low-energy counterparts of the unidentified or unassociated gamma-ray sources listed in the Fermi catalogs. Confirming RWBLs is a challenging task since they could be confused with white dwarfs (WDs) or weak emission line quasars (WELQs) when there are not sufficient data to precisely draw their broadband spectral energy distribution, and their classification is mainly based on a featureless optical spectra. Motivated by the recent discovery that Fermi BL Lacs appear to have very peculiar mid-IR emission, we show that it is possible to distinguish between WDs, WELQs, and BL Lacs using the [3.4]–[4.6]–[12] μ m color–color plot built using the WISE magnitudes when the optical spectrum is available. On the basis of this analysis, we identify WISE J064459.38+603131 and WISE J141046.00+740511.2 as the first two genuine RWBLs, both potentially associated with Fermi sources. Finally, to strengthen our identification of these objects as true RWBLs, we present multifrequency observations for these two candidates to show that their spectral behavior is indeed consistent with that of the BL Lac population.

Time-dependent inhomogeneous jet models for BL Lac objects

Science.gov (United States)

Marlowe, A. T.; Urry, C. M.; George, I. M.

1992-05-01

Relativistic beaming can explain many of the observed properties of BL Lac objects (e.g., rapid variability, high polarization, etc.). In particular, the broadband radio through X-ray spectra are well modeled by synchrotron-self Compton emission from an inhomogeneous relativistic jet. We have done a uniform analysis on several BL Lac objects using a simple but plausible inhomogeneous jet model. For all objects, we found that the assumed power-law distribution of the magnetic field and the electron density can be adjusted to match the observed BL Lac spectrum. While such models are typically unconstrained, consideration of spectral variability strongly restricts the allowed parameters, although to date the sampling has generally been too sparse to constrain the current models effectively. We investigate the time evolution of the inhomogeneous jet model for a simple perturbation propagating along the jet. The implications of this time evolution model and its relevance to observed data are discussed.

Crisis in LAC : Infrastructure Investment, Employment and the Expectations of Stimulus

OpenAIRE

Schwartz, Jordan; Andres, Luis; Dragoiu, Georgeta

2009-01-01

Infrastructure investment is a central part of the stimulus plans of the Latin America and the Caribbean (LAC) region as it confronts the growing financial crisis. This paper estimates the potential effects on direct, indirect, and induced employment for different types of infrastructure projects with LAC-specific variables. The analysis finds that the direct and indirect short-term employ...

In vivo biocompatibility of p(HPMAm-lac)-PEG hydrogels hybridized with hyaluronan

NARCIS (Netherlands)

Sabbieti, Maria Giovanna; Dubbini, Alessandra; Laus, Fulvio; Paggi, Emanuele; Marchegiani, Andrea; Capitani, Melania; Marchetti, Luigi; Dini, Fabrizio; Vermonden, Tina; Di Martino, Piera; Agas, Dimitrios; Censi, Roberta

2017-01-01

The present study reports on the biocompatibility in vivo after intramuscular and subcutaneous administration in Balb/c mice of vinyl sulphone bearing p(HPMAm-lac1-2)-PEG-p(HPMAm-lac1-2)/thiolated hyaluronic acid hydrogels, designed as novel injectable biomaterials for potential application in the

Can blueshifted Agn spectra explain B L Lac objects

International Nuclear Information System (INIS)

Basu, D.

2009-01-01

B L Lac spectra are almost completely devoid of any emission line, and absorption features are often present based on which redshifts are estimated. Several models have been proposed to explain the spectra, including the unification scheme currently most popular among astronomers. However, there appear to be ambiguities, uncertainties and contradictory results in this model, and many questions remain unanswered. Also, it involves the process of artificially enhancing the continuum to be concentrated to a high level, by the relativistically beaming jet action, in order to submerge the emission lines, partly or completely, to make them appear weak or invisible. Additionally, the sample based on which B L Lac objects have been included in the unification scheme is rather small to be statistically viable. In this context, we present an alternative and much simpler interpretation of the observed spectra of B L Lac objects, both emission and absorption, as blueshifted lines in Agn. Original spectra of fifty six objects available in the current literature are re-analyzed. Nine of these show only a single weak emission line and no absorption feature, while thirty five exhibit no emission feature but several absorption lines, and another twelve show more than one emission line and, in some cases, several absorption lines. It is demonstrated that emission lines in most B L Lac objects are blueshifted out of the visible region, and, hence, not seen at all. Emission lines, when seen, and absorption lines, are blueshifted and are identified with search lines of longer wavelengths that are naturally weak. Blue shifts, in emission and absorption features, are determined for all objects. Various considerations lead to the conclusion that the blue shift interpretation of B L Lac spectra is superior to and more important than the redshift interpretation. A possible explanation of observed blue shifts is presented in the scenario of the ejection process, a well-recognized mechanism

République de Djibouti : lac Assal [بحيرة عسل

OpenAIRE

Pouyllau , Stéphane

2009-01-01

Vue des berges sud-est du lac Assal (République de Djibouti) le 11 novembre 2009. Le Lac Assal est un lac salé endoréique situé au fond du golfe du Ghoubbet-el-Kharab. D'une superficie de 54 km2 et fermé de la mer par le volcan Ardoukôba, sont altitude est de -153m sous le niveau de la mer.

Multi-Wave Luminosity of High-Synchrotron-Peaked TeV BL Lacs ...

Indian Academy of Sciences (India)

LIR, Lγ) in the radio, near-infrared and γ-ray wave bands for HSP. TeV BL Lacs. The results show that there are significant intrinsic cor- relations between LR and Lγ and between LIR and Lγ in all states. (high/average/low), and suggest that for HSP TeV BL Lacs, the Syn- chrotron Self-Compton radiation (SSC) is the main ...

STRUCTURAL ASPECTS REGARDING TO THE IMAGE OF ICE HOTEL BALEA LAC BREND

Directory of Open Access Journals (Sweden)

Marian ZAHARIA

2008-06-01

Full Text Available Applying a poll-based survey provides important information regarding the tourist offer particulars in Bâlea Lac area. On the day the survey is performed its main advantage is also outlined: the fact that this information display a good accuracy, are obtained in a short time span and involving relatively low expenses. Data collection and centralization of the answers provided by interviewed tourists regarding tourism practice in the Bâlea Lac area have led to drawing up distributions that are presented in the paper. Based on the respective information, statistics methods adequate to the study of tourist opinion on the Bâlea Lac Ice Hotel brand image. Several issues have been outlined, regarding the types of respondents based on their category, Romanian or foreigners, from Romania and based on destination countries, function of: the type of stay; the means of information; their answers referring to their first arrival at Bâlea Lac; the degree of destination assessment; their opinion on host reception; their preference for Bâlea Lac; appreciating value for money; age groups; gender; social and professional standing. The image created through the attractions and services provided in the Bâlea Lac tourist area by tourism activities closely related to the Ice Hotel is well appreciated, so that they have opened up a rather favourable expectancy for those willing to come back and for those tempted to try and spend their holidays in the presented hotel.

Multi-wavelength studies of TeV γ-ray emitting BL Lac objects

International Nuclear Information System (INIS)

Kaufmann, Sarah Sabine

2012-01-01

The discovery of TeV γ-ray emission of BL Lac objects gave new insights in the particle acceleration and the emission processes of the highly relativistic jets. To shed light on the conditions in the high energetic jets of the TeV γ-ray emitting BL Lac objects, I have studied in great detail the spectral energy distribution (SED) of sources with different characteristics. BL Lac objects with exceptional very high energy spectra (soft and hard spectra) and with large differences in the emission peak frequencies, to cover the different classes of BL Lac objects, have been chosen. The basic aim of this thesis was, to study with new, simultaneous multi- avelength (MWL) observations, if the emission processes of these extreme cases of TeV BL Lac objects can be explained by the synchrotron Self-Compton (SSC) model which is well established for the class of BL Lac objects at lower energies. We proposed MWL observations in the optical, UV and X-ray regime, to be conducted simultaneous to very high energy observations with the H.E.S.S. experiment, to study the emission processes. Simultaneous observations are crucial, since BL Lac objects are variable at all wavebands. I have analysed the MWL observations and conducted detailed variability and spectral studies in each wavelength range. The different kind of absorption at each wavelength as well as the influence of the host galaxy of the AGN has been considered to obtain the intrinsic jet spectrum. I have then applied the commonly used theoretical jet model, the SSC model, to the SED. I conducted a MWL campaign on a BL Lac object with the softest TeV spectrum, PKS 2005-489, during which it was observed in a very bright X-ray state. The good spectral coverage of the emission peaks allowed a detailed study of the SSC model. The extreme BL Lac object 1ES 0229+200 exhibits a hard intrinsic TeV spectrum. With my MWL campaign I found a clear cut-off in the optical range and therefore a high minimum Lorentz factor is needed to

Multi-wavelength studies of TeV γ-ray emitting BL Lac objects

Energy Technology Data Exchange (ETDEWEB)

Kaufmann, Sarah Sabine

2012-12-21

The discovery of TeV γ-ray emission of BL Lac objects gave new insights in the particle acceleration and the emission processes of the highly relativistic jets. To shed light on the conditions in the high energetic jets of the TeV γ-ray emitting BL Lac objects, I have studied in great detail the spectral energy distribution (SED) of sources with different characteristics. BL Lac objects with exceptional very high energy spectra (soft and hard spectra) and with large differences in the emission peak frequencies, to cover the different classes of BL Lac objects, have been chosen. The basic aim of this thesis was, to study with new, simultaneous multi- avelength (MWL) observations, if the emission processes of these extreme cases of TeV BL Lac objects can be explained by the synchrotron Self-Compton (SSC) model which is well established for the class of BL Lac objects at lower energies. We proposed MWL observations in the optical, UV and X-ray regime, to be conducted simultaneous to very high energy observations with the H.E.S.S. experiment, to study the emission processes. Simultaneous observations are crucial, since BL Lac objects are variable at all wavebands. I have analysed the MWL observations and conducted detailed variability and spectral studies in each wavelength range. The different kind of absorption at each wavelength as well as the influence of the host galaxy of the AGN has been considered to obtain the intrinsic jet spectrum. I have then applied the commonly used theoretical jet model, the SSC model, to the SED. I conducted a MWL campaign on a BL Lac object with the softest TeV spectrum, PKS 2005-489, during which it was observed in a very bright X-ray state. The good spectral coverage of the emission peaks allowed a detailed study of the SSC model. The extreme BL Lac object 1ES 0229+200 exhibits a hard intrinsic TeV spectrum. With my MWL campaign I found a clear cut-off in the optical range and therefore a high minimum Lorentz factor is needed to

Dynamics and bistability in a reduced model of the lac operon

Science.gov (United States)

Yildirim, Necmettin; Santillán, Moisés; Horike, Daisuke; Mackey, Michael C.

2004-06-01

It is known that the lac operon regulatory pathway is capable of showing bistable behavior. This is an important complex feature, arising from the nonlinearity of the involved mechanisms, which is essential to understand the dynamic behavior of this molecular regulatory system. To find which of the mechanisms involved in the regulation of the lac operon is the origin of bistability, we take a previously published model which accounts for the dynamics of mRNA, lactose, allolactose, permease and β-galactosidase involvement and simplify it by ignoring permease dynamics (assuming a constant permease concentration). To test the behavior of the reduced model, three existing sets of data on β-galactosidase levels as a function of time are simulated and we obtain a reasonable agreement between the data and the model predictions. The steady states of the reduced model were numerically and analytically analyzed and it was shown that it may indeed display bistability, depending on the extracellular lactose concentration and growth rate.

The SOS-LUX-LAC-FLUORO-Toxicity-test on the International Space Station (ISS).

Science.gov (United States)

Rabbow, E; Rettberg, P; Baumstark-Khan, C; Horneck, G

2003-01-01

In the 21st century, an increasing number of astronauts will visit the International Space Station (ISS) for prolonged times. Therefore it is of utmost importance to provide necessary basic knowledge concerning risks to their health and their ability to work on the station and during extravehicular activities (EVA) in free space. It is the aim of one experiment of the German project TRIPLE-LUX (to be flown on the ISS) to provide an estimation of health risk resulting from exposure of the astronauts to the radiation in space inside the station as well as during extravehicular activities on one hand, and of exposure of astronauts to unavoidable or as yet unknown ISS-environmental genotoxic substances on the other. The project will (i) provide increased knowledge of the biological action of space radiation and enzymatic repair of DNA damage, (ii) uncover cellular mechanisms of synergistic interaction of microgravity and space radiation and (iii) examine the space craft milieu with highly specific biosensors. For these investigations, the bacterial biosensor SOS-LUX-LAC-FLUORO-Toxicity-test will be used, combining the SOS-LUX-Test invented at DLR Germany (Patent) with the commercially available LAC-FLUORO-Test. The SOS-LUX-Test comprises genetically modified bacteria transformed with the pBR322-derived plasmid pPLS-1. This plasmid carries the promoterless lux operon of Photobacterium leiognathi as a reporter element under control of the DNA-damage dependent SOS promoter of ColD as sensor element. This system reacts to radiation and other agents that induce DNA damages with a dose dependent measurable emission of bioluminescence of the transformed bacteria. The analogous LAC-FLUORO-Test has been developed for the detection of cellular responses to cytotoxins. It is based on the constitutive expression of green fluorescent protein (GFP) mediated by the bacterial protein expression vector pGFPuv (Clontech, Palo Alto, USA). In response to cytotoxic agents, this system

Laccase 1 gene from Plutella xylostella (PxLac1) and its functions in humoral immune response.

Science.gov (United States)

Wang, Ze-Hua; Hu, Rong-Min; Ye, Xi-Qian; Huang, Jian-Hua; Chen, Xue-Xin; Shi, Min

Laccase (EC 1.10.3.2) is a phenoloxidase found in many insect species. The Laccase 1 gene from Plutella xylostella (PxLac1) was cloned, and its expression patterns and functions were determined using qPCR and RNAi methods. The results showed that the expression levels of PxLac1 were consistently high in all larval stages, and the most abundant was in the midgut during the 4th instar stage. Moreover, the expression of PxLac1 was up-regulated in response to bacterial infection, and decreased 24 h after being parasitized by Cotesia vestalis. Further analyses indicated that the effect of parasitization on PxLac1 was induced by active C. vestalis Bracovirus (CvBV). Haemocyte-free hemolymph phenoloxidase (PO) activity was suppressed when PxLac1 was treated with RNAi. Our results provide evidence for a connection between the Laccase 1 gene and insect immunity, and revealed that parasitoid polydnavirus suppresses host PO activity via PxLac1 regulation. Copyright © 2018. Published by Elsevier Ltd.

Enzymatic Synthesis of N-Acetyllactosamine (LacNAc Type 1 Oligomers and Characterization as Multivalent Galectin Ligands

Directory of Open Access Journals (Sweden)

Thomas Fischöder

2017-08-01

Full Text Available Repeats of the disaccharide unit N-acetyllactosamine (LacNAc occur as type 1 (Galβ1, 3GlcNAc and type 2 (Galβ1, 4GlcNAc glycosylation motifs on glycoproteins and glycolipids. The LacNAc motif acts as binding ligand for lectins and is involved in many biological recognition events. To the best of our knowledge, we present, for the first time, the synthesis of LacNAc type 1 oligomers using recombinant β1,3-galactosyltransferase from Escherichia coli and β1,3-N-acetylglucosaminyltranferase from Helicobacter pylori. Tetrasaccharide glycans presenting LacNAc type 1 repeats or LacNAc type 1 at the reducing or non-reducing end, respectively, were conjugated to bovine serum albumin as a protein scaffold by squarate linker chemistry. The resulting multivalent LacNAc type 1 presenting neo-glycoproteins were further studied for specific binding of the tumor-associated human galectin 3 (Gal-3 and its truncated counterpart Gal-3∆ in an enzyme-linked lectin assay (ELLA. We observed a significantly increased affinity of Gal-3∆ towards the multivalent neo-glycoprotein presenting LacNAc type 1 repeating units. This is the first evidence for differences in glycan selectivity of Gal-3∆ and Gal-3 and may be further utilized for tracing Gal-3∆ during tumor progression and therapy.

VizieR Online Data Catalog: The CLASS BL Lac sample (Marcha+, 2013)

Science.gov (United States)

Marcha, M. J. M.; Caccianiga, A.

2014-04-01

This paper presents a new sample of BL Lac objects selected from a deep (30mJy) radio survey of flat spectrum radio sources (the CLASS blazar survey). The sample is one of the largest well-defined samples in the low-power regime with a total of 130 sources of which 55 satisfy the 'classical' optical BL Lac selection criteria, and the rest have indistinguishable radio properties. The primary goal of this study is to establish the radio luminosity function (RLF) on firm statistical ground at low radio luminosities where previous samples have not been able to investigate. The gain of taking a peek at lower powers is the possibility to search for the flattening of the luminosity function which is a feature predicted by the beaming model but which has remained elusive to observational confirmation. In this study, we extend for the first time the BL Lac RLF down to very low radio powers ~1022W/Hz, i.e. two orders of magnitude below the RLF currently available in the literature. In the process, we confirm the importance of adopting a broader, and more physically meaningful set of classification criteria to avoid the systematic missing of low-luminosity BL Lacs. Thanks to the good statistics we confirm the existence of weak but significant positive cosmological evolution for the BL Lac population, and we detect, for the first time the flattening of the RLF at L~1025W/Hz in agreement with the predictions of the beaming model. (1 data file).

PRODUCTION HALIEUTIQUE DU LAC FAE (BASSIN DU SAN ...

African Journals Online (AJOL)

about 5.229 millions CFA for the shrimp production at the rate of 1500 Flkg. .... Figure 1 Lac Fae-Localisation geographique, zones de production, secteurs et ... embankment dam ; d : water intake for regulating the threshold level of water in the.

Water quality and hydrology of the Lac Vieux Desert watershed, Gogebic County, Michigan, and Vilas County, Wisconsin, 2002-04

Science.gov (United States)

Weaver, T.L.; Neff, B.P.; Ellis, J.M.

2005-01-01

Lac Vieux Desert is a prominent 6.6 square-mile lake that straddles the Michigan-Wisconsin border and forms the headwaters of the Wisconsin River. For generations, the Lac Vieux Desert Band of Lake Superior Chippewa Indians have used Lac Vieux Desert and the surrounding area for growing and harvesting wild rice, and hunting and fishing. The Lac Vieux Desert Band is concerned about the impact of lake-stage regulation on hydrology and ecology, and the impact on water quality of development along and near the shore, and recreational watercraft use and sport fishing. In 2005, the U.S. Geological Survey completed a water-resources investigation of the Lac Vieux Desert watershed in cooperation with the Lac Vieux Desert Band of Lake Superior Chippewa Indians.Water quality of Lac Vieux Desert is typical of many lakes in the northern United States. Trophic State Index calculations classify Lac Vieux Desert as a highly productive eutrophic lake. The pH of water in Lac Vieux Desert ranged from 6.5 to 9.5, and specific conductance ranged from 62 to 114 µs/cm. Chloride concentration was less than 1.5 mg/L, indicating little effect from septic-tank or road-salt input. Results indicate that the water can be classified as soft, with hardness concentrations reported as calcium carbonate ranging from 29 to 49 mg/L. Concentrations of calcium, magnesium, chloride, and other dissolved solids ranged from 47 to 77 mg/L. Alkalinity of Lac Vieux Desert ranged from 27 to 38 mg/L.Pervasive aquatic blooms, including a bloom noted during the September 2003 sampling, are apparently common in late summer. Biological productivity at Lac Vieux Desert does not appear to have changed appreciably between 1973 and 2004. In the current study, total phosphorus concentrations ranged from 0.01 to 0.064 mg/L and dissolved nitrite plus nitrate nitrogen concentrations ranged from at, or below detection limit to 0.052 mg/L. Overabundance of nutrients in Lac Vieux Desert, particularly nitrogen and phosphorus

The LHC personnel safety system

International Nuclear Information System (INIS)

Ninin, P.; Valentini, F.; Ladzinski, T.

2011-01-01

Large particle physics installations such as the CERN Large Hadron Collider require specific Personnel Safety Systems (PSS) to protect the personnel against the radiological and industrial hazards. In order to fulfill the French regulation in matter of nuclear installations, the principles of IEC 61508 and IEC 61513 standard are used as a methodology framework to evaluate the criticality of the installation, to design and to implement the PSS.The LHC PSS deals with the implementation of all physical barriers, access controls and interlock devices around the 27 km of underground tunnel, service zones and experimental caverns of the LHC. The system shall guarantee the absence of personnel in the LHC controlled areas during the machine operations and, on the other hand, ensure the automatic accelerator shutdown in case of any safety condition violation, such as an intrusion during beam circulation. The LHC PSS has been conceived as two separate and independent systems: the LHC Access Control System (LACS) and the LHC Access Safety System (LASS). The LACS, using off the shelf technologies, realizes all physical barriers and regulates all accesses to the underground areas by identifying users and checking their authorizations.The LASS has been designed according to the principles of the IEC 61508 and 61513 standards, starting from a risk analysis conducted on the LHC facility equipped with a standard access control system. It consists in a set of safety functions realized by a dedicated fail-safe and redundant hardware guaranteed to be of SIL3 class. The integration of various technologies combining electronics, sensors, video and operational procedures adopted to establish an efficient personnel safety system for the CERN LHC accelerator is presented in this paper. (authors)

Spectroscopy of optically selected BL Lac objects and their γ-ray emission

Energy Technology Data Exchange (ETDEWEB)

Sandrinelli, A.; Treves, A.; Farina, E. P.; Landoni, M. [Università degli Studi dell' Insubria, Via Valleggio 11, I-22100 Como (Italy); Falomo, R. [INAF-Osservatorio Astronomico di Padova, Vicolo dell Osservatorio 5, I-35122 Padova (Italy); Foschini, L.; Sbarufatti, B., E-mail: angela.sandrinelli@brera.inaf.it [INAF-Osservatorio Astronomico di Brera, Via Emilio Bianchi 46, I-23807 Merate (Italy)

2013-12-01

We present Very Large Telescope optical spectroscopy of nine BL Lac objects of unknown redshift belonging to the list of optically selected radio-loud BL Lac candidates. We explore their spectroscopic properties and possible link with gamma-ray emission. From the new observations we determine the redshifts of four objects from faint emission lines or from absorption features of their host galaxies. In three cases we find narrow intervening absorptions from which a lower limit to the redshift is inferred. For the remaining two featureless sources, lower limits to the redshift are deduced from the absence of spectral lines. A search for γ counterpart emission shows that six out of the nine candidates are Fermi γ-ray emitters and we find two new detections. Our analysis suggests that most of the BL Lac objects still lacking redshift information are most likely located at high redshifts.

THE CONTRIBUTION OF FERMI -2LAC BLAZARS TO DIFFUSE TEV–PEV NEUTRINO FLUX

Energy Technology Data Exchange (ETDEWEB)

Aartsen, M. G. [Department of Physics, University of Adelaide, Adelaide, 5005 (Australia); Abraham, K. [Physik-department, Technische Universität München, D-85748 Garching (Germany); Ackermann, M. [DESY, D-15735 Zeuthen (Germany); Adams, J. [Dept. of Physics and Astronomy, University of Canterbury, Private Bag 4800, Christchurch (New Zealand); Aguilar, J. A.; Ansseau, I. [Université Libre de Bruxelles, Science Faculty CP230, B-1050 Brussels (Belgium); Ahlers, M. [Dept. of Physics and Wisconsin IceCube Particle Astrophysics Center, University of Wisconsin, Madison, WI 53706 (United States); Ahrens, M. [Oskar Klein Centre and Dept. of Physics, Stockholm University, SE-10691 Stockholm (Sweden); Altmann, D.; Anton, G. [Erlangen Centre for Astroparticle Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg, D-91058 Erlangen (Germany); Andeen, K. [Department of Physics, Marquette University, Milwaukee, WI, 53201 (United States); Anderson, T.; Arlen, T. C. [Dept. of Physics, Pennsylvania State University, University Park, PA 16802 (United States); Archinger, M.; Baum, V. [Institute of Physics, University of Mainz, Staudinger Weg 7, D-55099 Mainz (Germany); Arguelles, C.; Axani, S. [Dept. of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Auffenberg, J. [III. Physikalisches Institut, RWTH Aachen University, D-52056 Aachen (Germany); Bai, X. [Physics Department, South Dakota School of Mines and Technology, Rapid City, SD 57701 (United States); Barwick, S. W., E-mail: thorsten.gluesenkamp@fau.de [Dept. of Physics and Astronomy, University of California, Irvine, CA 92697 (United States); Collaboration: IceCube Collaboration; and others

2017-01-20

The recent discovery of a diffuse cosmic neutrino flux extending up to PeV energies raises the question of which astrophysical sources generate this signal. Blazars are one class of extragalactic sources which may produce such high-energy neutrinos. We present a likelihood analysis searching for cumulative neutrino emission from blazars in the 2nd Fermi -LAT AGN catalog (2LAC) using IceCube neutrino data set 2009-12, which was optimized for the detection of individual sources. In contrast to those in previous searches with IceCube, the populations investigated contain up to hundreds of sources, the largest one being the entire blazar sample in the 2LAC catalog. No significant excess is observed, and upper limits for the cumulative flux from these populations are obtained. These constrain the maximum contribution of 2LAC blazars to the observed astrophysical neutrino flux to 27% or less between around 10 TeV and 2 PeV, assuming the equipartition of flavors on Earth and a single power-law spectrum with a spectral index of −2.5. We can still exclude the fact that 2LAC blazars (and their subpopulations) emit more than 50% of the observed neutrinos up to a spectral index as hard as −2.2 in the same energy range. Our result takes into account the fact that the neutrino source count distribution is unknown, and it does not assume strict proportionality of the neutrino flux to the measured 2LAC γ -ray signal for each source. Additionally, we constrain recent models for neutrino emission by blazars.

METHODICAL APPROACHES TO THE CREATION MOOC (EXPERIENCE LAC

Directory of Open Access Journals (Sweden)

Larysa Nozdrina

2016-03-01

Full Text Available The article presents a number of problems, determining the current state of development of the domestic market of massive open online courses (MOOC. Considering the aim of the research, there is described national experience in this area, proposed and substantiated a number of the criteria and methodological approaches to the implementation of MOOC in higher education. The development of MOOC in the Lviv Academy of Commerce (LAC is reviewed as example. The main factors which determine the success of this educational innovation in the domestic market and are put under the research are software platforms, multimedia software for creating video lectures, course structure and support the learning process. The results of study which have been analyzed in this course can have a positive impact on the functioning of the market MOOC in Ukrainian universities. The article focuses on finding the ways of improving the process of developing and implementing MOOC in higher education in the example of LAC where Web-center on the MOODLE platform is used for e-learning. Further research should focus on the development of institutional mechanisms to ensure the effective design, implementation and operation of the MOOC in the universities in Ukraine. Particular attention during learning in massive open online course should be aimed at improving the educational process and to strengthen student's motivation in MOOC. Experience of MOOC's development in LAC can be useful at creating similar courses at other institutions of higher education in the different platforms, both MOODLE, and on the others

Bistable behavior of the lac operon in E. coli when induced with a mixture of lactose and TMG

Directory of Open Access Journals (Sweden)

Orlando Díaz-Hernández

2010-07-01

Full Text Available In this work we investigate multistability in the lac operon of Escherichia coli when it is induced by a mixture of lactose and the non-metabolizable thiomethyl galactoside (TMG. In accordance with previously published experimental results and computer simulations, our simulations predict that: (1 when the system is induced by TMG, the system shows a discernible bistable behavior while, (2 when the system is induced by lactose, bistability does not disappear but excessively high concentrations of lactose would be required to observe it. Finally, our simulation results predict that when a mixture of lactose and TMG is used, the bistability region in the extracellular glucose concentration vs. extracellular lactose concentration parameter space changes in such a way that the model predictions regarding bistability could be tested experimentally. These experiments could help to solve a recent controversy regarding the existence of bistability in the lac operon under natural conditions.

Bistable behavior of the lac operon in E. coli when induced with a mixture of lactose and TMG.

Science.gov (United States)

Díaz-Hernández, Orlando; Santillán, Moisés

2010-01-01

In this work we investigate multistability in the lac operon of Escherichia coli when it is induced by a mixture of lactose and the non-metabolizable thiomethyl galactoside (TMG). In accordance with previously published experimental results and computer simulations, our simulations predict that: (1) when the system is induced by TMG, the system shows a discernible bistable behavior while, (2) when the system is induced by lactose, bistability does not disappear but excessively high concentrations of lactose would be required to observe it. Finally, our simulation results predict that when a mixture of lactose and TMG is used, the bistability region in the extracellular glucose concentration vs. extracellular lactose concentration parameter space changes in such a way that the model predictions regarding bistability could be tested experimentally. These experiments could help to solve a recent controversy regarding the existence of bistability in the lac operon under natural conditions.

CLUSTERING OF γ-RAY-SELECTED 2LAC FERMI BLAZARS

Energy Technology Data Exchange (ETDEWEB)

Allevato, V.; Finoguenov, A. [Department of Physics, University of Helsinki, Gustaf Hällströmin katu 2a, FI-00014 Helsinki (Finland); Cappelluti, N. [University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250 (United States)

2014-12-20

We present the first measurement of the projected correlation function of 485 γ-ray-selected blazars, divided into 175 BL Lacertae (BL Lacs) and 310 flat-spectrum radio quasars (FSRQs) detected in the 2 year all-sky survey by the Fermi-Large Area Telescope. We find that Fermi BL Lacs and FSRQs reside in massive dark matter halos (DMHs) with log M{sub h} = 13.35{sub −0.14}{sup +0.20} and log M{sub h} = 13.40{sub −0.19}{sup +0.15} h {sup –1} M {sub ☉}, respectively, at low (z ∼ 0.4) and high (z ∼ 1.2) redshift. In terms of clustering properties, these results suggest that BL Lacs and FSRQs are similar objects residing in the same dense environment typical of galaxy groups, despite their different spectral energy distributions, power, and accretion rates. We find no difference in the typical bias and hosting halo mass between Fermi blazars and radio-loud active galactic nuclei (AGNs), supporting the unification scheme simply equating radio-loud objects with misaligned blazar counterparts. This similarity in terms of the typical environment they preferentially live in, suggests that blazars tend to occupy the center of DMHs, as already pointed out for radio-loud AGNs. This implies, in light of several projects looking for the γ-ray emission from DM annihilation in galaxy clusters, a strong contamination from blazars to the expected signal from DM annihilation.

Louisiana SIP: LAC 33:III Ch 21 Subchap J, 2147--Limiting Volatile Organic Compound (VOC) Emissions from Reactor Processes and Distillation Operations in Synthetic Organic Chemical manufacturing Industry (SOCMI); SIP effective 1998-02-02 (LAc74) to more..

Science.gov (United States)

Louisiana SIP: LAC 33:III Ch 21 Subchap J, 2147--Limiting Volatile Organic Compound (VOC) Emissions from Reactor Processes and Distillation Operations in Synthetic Organic Chemical manufacturing Industry (SOCMI); SIP effective 1998-02-02 (LAc74) more...

The BL Lac objects PKS 1144-379

International Nuclear Information System (INIS)

Nicolson, G.D.; Glass, I.S.; Feast, M.W.; Andrews, P.J.

1979-01-01

The highly variable radio source PKS 1144-379 has been monitored at 13 cm and 6 cm over a period of 3 years. It has been identified with an object whose photographic image is star-like. From infrared photometry, UBVRsub(KC)Isub(KC) photometry and spectroscopy, it is concluded that PKS 1144-379 is a BL Lac object with msub(v) approximately = 16.2. (author)

Gtl2lacZ, an insertional mutation on mouse chromosome 12 with parental origin-dependent phenotype.

Science.gov (United States)

Schuster-Gossler, K; Simon-Chazottes, D; Guenet, J L; Zachgo, J; Gossler, A

1996-01-01

We have produced a transgenic mouse line, Gtl2lacZ (Gene trap locus 2), that carries an insertional mutation with a dominant modified pattern of inheritance:heterozygous Gtl2lacZ mice that inherited the transgene from the father show a proportionate dwarfism phenotype, whereas the penetrance and expressivity of the phenotype is strongly reduced in Gtl2lacZ mice that inherited the transgene from the mother. On a mixed genetic background this pattern of inheritance was reversible upon transmission of the transgene through the germ line of the opposite sex. On a predominantly 129/Sv genetic background, however, transgene passage through the female germ line modified the transgene effect, such that the penetrance of the mutation was drastically reduced and the phenotype was no longer obvious after subsequent male germ line transmission. Expression of the transgene, however, was neither affected by genetic background nor by parental legacy. Gtl2lacZ maps to mouse Chromosome 12 in a region that displays imprinting effects associated with maternal and paternal disomy. Our results suggest that the transgene insertion in Gtl2lacZ mice affects an endogenous gene(s) required for fetal and postnatal growth and that this gene(s) is predominantly paternally expressed.

Lac repressor: Crystallization of intact tetramer and its complexes with inducer and operator DNA

International Nuclear Information System (INIS)

Pace, H.C.; Lu, P.; Lewis, M.

1990-01-01

The intact lac repressor tetramer, which regulates expression of the lac operon in Escherichia coli, has been crystallized in the native form, with an inducer, and in a ternary complex with operator DNA and an anti-inducer. The crystals without DNA diffract to better than 3.5 angstrom. They belong to the monoclinic space group C2 and have cell dimensions a = 164.7 angstrom, b = 75.6 angstrom, and c = 161.2 angstrom, with α = γ = 90 degree and β = 125.5 degree. Cocrystals have been obtained with a number of different lac operator-related DNA fragments. The complex with a blunt-ended 16-base-pair strand yielded tetragonal bipyramids that diffract to 6.5 angstrom. These protein-DNA cocrystals crack upon exposure to the gratuitous inducer isopropyl β-D-thiogalactoside, suggesting a conformational change in the repressor-operator complex

Variabilité journalière de la qualité physico-chimique du lac M'koa ...

African Journals Online (AJOL)

d'enrichissement en matières organique, azote et phosphore capables d'influer sur la teneur de saturation en oxygène dissous. La Figure 4 montre des lavandiers communément appelés "fanico" exerçant leur activité quotidienne au lac. Cette activité est source d'enrichissement des eaux du lac. M'koa en phosphore et ...

Characterization of pLAC1, a cryptic plasmid isolated from Lactobacillus acidipiscis and comparative analysis with its related plasmids.

Science.gov (United States)

Asteri, Ioanna-Areti; Papadimitriou, Konstantinos; Boutou, Effrossyni; Anastasiou, Rania; Pot, Bruno; Vorgias, Constantinos E; Tsakalidou, Effie

2010-07-15

The pLAC1 plasmid of Lactobacillus acidipiscis ACA-DC 1533, a strain isolated from traditional Kopanisti cheese, was characterised. Nucleotide sequence analysis revealed a circular molecule of 3478bp with a G+C content of 37.2%. Ab initio annotation indicated four putative open reading frames (orfs). orf1 and orf4 were found to encode a replication initiation protein (Rep) and a mobilization protein (Mob), respectively. The deduced products of orf2 and orf3 revealed no significant homology to other known proteins. However, in silico examination of the plasmid sequence supported the existence of a novel operon that includes rep, orf2 and orf3 in pLAC1 and that this operon is highly conserved also in plasmids pLB925A02, pSMA23, pLC88 and pC7. RT-PCR experiments allowed us to verify that these three genes are co-transcribed as a single polycistronic mRNA species. Furthermore, phylogenetic analysis of pLAC1 Rep and Mob proteins demonstrated that they may have derived from different plasmid origins, suggesting that pLAC1 is a product of a modular evolution process. Comparative analysis of full length nucleotide sequences of pLAC1 and related Lactobacillus plasmids showed that pLAC1 shares a very similar replication backbone with pLB925A02, pSMA23 and pLC88. In contrast, mob of pLAC1 was almost identical with the respective gene of plasmids pLAB1000, pLB4 and pPB1. These findings lead to the conclusion that pLAC1 acquired mob probably via an ancestral recombination event. Our overall work highlights the importance of characterizing plasmids deriving from non-starter 'wild' isolates in order to better appreciate plasmid divergence and evolution of lactic acid bacteria. 2010 Elsevier B.V. All rights reserved.

A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions

International Nuclear Information System (INIS)

Cupples, C.G.; Miller, J.H.

1989-01-01

We describe the construction of six strains of Escherichia coli with different mutations at the same coding position in the lacZ gene, which specifies the active site glutamic acid residue at position 461 in beta'-galactosidase. Each strain is Lac- and reverts to Lac+ only by restoring the glutamic acid codon. The strains have been designed so that each reverts via one of the six base substitutions. The set of strains allows detection of each transition and transversion simply by monitoring the Lac- to Lac+ frequency, as demonstrated here with characterized mutagens and mutator alleles. These strains are useful for rapidly determining the mutagenic specificity of mutagens at a single site, for detecting low levels of stimulation of certain base substitutions, for monitoring specific base changes in response to various experimental conditions or strain backgrounds, and for isolating new mutator strains

USING THE METHODS OF WAVELET ANALYSIS AND SINGULAR SPECTRUM ANALYSIS IN THE STUDY OF RADIO SOURCE BL LAC

OpenAIRE

Donskykh, G. I.; Ryabov, M. I.; Sukharev, A. I.; Aller, M.

2014-01-01

We investigated the monitoring data of extragalactic source BL Lac. This monitoring was held withUniversityofMichigan26-meter radio  telescope. To study flux density of extragalactic source BL Lac at frequencies of 14.5, 8 and 4.8 GHz, the wavelet analysis and singular spectrum analysis were used. Calculating the integral wavelet spectra allowed revealing long-term  components  (~7-8 years) and short-term components (~ 1-4 years) in BL Lac. Studying of VLBI radio maps (by the program Mojave) ...

Hopf Bifurcation and Delay-Induced Turing Instability in a Diffusive lac Operon Model

Science.gov (United States)

Cao, Xin; Song, Yongli; Zhang, Tonghua

In this paper, we investigate the dynamics of a lac operon model with delayed feedback and diffusion effect. If the system is without delay or the delay is small, the positive equilibrium is stable so that there are no spatial patterns formed; while the time delay is large enough the equilibrium becomes unstable so that rich spatiotemporal dynamics may occur. We have found that time delay can not only incur temporal oscillations but also induce imbalance in space. With different initial values, the system may have different spatial patterns, for instance, spirals with one head, four heads, nine heads, and even microspirals.

The clean development mechanism (CDM) an international perspective and implications for the LAC region

International Nuclear Information System (INIS)

2004-08-01

This paper addresses activity a) an analysis of international CDM experiences and its potential contribution to the LAC region. The paper begins with a section describing the basic principles of the CDM and retrieves the lessons learned from the first two years of the CDM operation. This is followed by a more detailed review in section 2 of the on-going baseline and monitoring methodology approval process. In section 3, the development value of the CDM is explored. Section 4 describes the current CDM markets, while section 5 reviews the response of host countries to the CDM outside the LAC region. Section 6 describes the various capacity building programs established by Annex 1 countries to support the CDM. In each of the first 6 sections, implications for the LAC region are identified. Section 7 brings these conclusions together into a concise summary. (The author)

In vitro transcription accurately predicts lac repressor phenotype in vivo in Escherichia coli

Directory of Open Access Journals (Sweden)

Matthew Almond Sochor

2014-07-01

Full Text Available A multitude of studies have looked at the in vivo and in vitro behavior of the lac repressor binding to DNA and effector molecules in order to study transcriptional repression, however these studies are not always reconcilable. Here we use in vitro transcription to directly mimic the in vivo system in order to build a self consistent set of experiments to directly compare in vivo and in vitro genetic repression. A thermodynamic model of the lac repressor binding to operator DNA and effector is used to link DNA occupancy to either normalized in vitro mRNA product or normalized in vivo fluorescence of a regulated gene, YFP. An accurate measurement of repressor, DNA and effector concentrations were made both in vivo and in vitro allowing for direct modeling of the entire thermodynamic equilibrium. In vivo repression profiles are accurately predicted from the given in vitro parameters when molecular crowding is considered. Interestingly, our measured repressor–operator DNA affinity differs significantly from previous in vitro measurements. The literature values are unable to replicate in vivo binding data. We therefore conclude that the repressor-DNA affinity is much weaker than previously thought. This finding would suggest that in vitro techniques that are specifically designed to mimic the in vivo process may be necessary to replicate the native system.

Assessment of aquifer properties, evapotranspiration, and the effects of ditching in the Stoney Brook watershed, Fond du Lac Reservation, Minnesota, 2006-9

Science.gov (United States)

Jones, Perry M.; Tomasek, Abigail A.

2015-01-01

The U.S. Geological Survey, in cooperation with the Fond du Lac Band of Lake Superior Chippewa, assessed hydraulic properties of geologic material, recharge, and evapotranspiration, and the effects of ditching on the groundwater resources in the Stoney Brook watershed in the Fond du Lac Reservation. Geologic, groundwater, and surface-water data were collected during 2006–9 to estimate hydrologic properties in the watershed. Streamflow and groundwater levels in the shallow glacial deposits in the Stoney Brook watershed were analyzed to estimate groundwater-flow directions, groundwater recharge, and evapotranspiration within the watershed and to assess the effect of ditches on surrounding groundwater resources. Groundwater, streamflow, and precipitation data collected during the study (2006–9) can be used to update the U.S. Department of Agriculture’s Natural Resource Conservation Service and Fond du Lac Resource Management Division surface-water models, which are used to evaluate the effect of proposed adjustments to the ditching system on streamflow on wild rice production and aquatic habitats.

Access control system operation

International Nuclear Information System (INIS)

Barnes, L.D.

1981-06-01

An automated method for the control and monitoring of personnel movement throughout the site was developed under contract to the Department of Energy by Allied-General Nuclear Services (AGNS) at the Barnwell Nuclear Fuel Plant (BNFP). These automated features provide strict enforcement of personnel access policy without routine patrol officer involvement. Identification methods include identification by employee ID number, identification by voice verification and identification by physical security officer verification. The ability to grant each level of access authority is distributed over the organization to prevent any single individual at any level in the organization from being capable of issuing an authorization for entry into sensitive areas. Each access event is recorded. As access events occur, the inventory of both the entered and the exited control area is updated so that a current inventory is always available for display. The system has been operated since 1979 in a development mode and many revisions have been implemented in hardware and software as areas were added to the system. Recent changes have involved the installation of backup systems and other features required to achieve a high reliability. The access control system and recent operating experience are described

Mutagenicity of ultraviolet A radiation in the lacI transgene in Big Blue mouse embryonic fibroblasts

International Nuclear Information System (INIS)

Kim, Sang-in; Pfeifer, Gerd P.; Besaratinia, Ahmad

2007-01-01

Sunlight ultraviolet A (UVA) irradiation has been implicated in the etiology of human skin cancer. A genotoxic mode of action for UVA radiation has been suggested that involves photosensitization reactions giving rise to promutagenic DNA lesions. We investigated the mutagenicity of UVA in the lacI transgene in Big Blue mouse embryonic fibroblasts. UVA irradiation of these cells at a physiologically relevant dose of 18 J/cm 2 caused a 2.8-fold increase in the lacI mutant frequency relative to control, i.e., 12.12 ± 1.84 versus 4.39 ± 1.99 x 10 -5 (mean ± S.D.). DNA sequencing analysis showed that of 100 UVA-induced mutant plaques and 54 spontaneously arisen control plaques, 97 and 51, respectively, contained a minimum of one mutation along the lacI transgene. The vast majority of both induced- and spontaneous mutations were single base substitutions, although less frequently, there were also single and multiple base deletions and insertions, and tandem base substitutions. Detailed mutation spectrometry analysis revealed that G:C → T:A transversions, the signature mutations of oxidative DNA damage, were significantly induced by UVA irradiation (P -5 ; P < 0.00001). These findings are in complete agreement with those previously observed in the cII transgene of the same model system, and reaffirm the notion that intracellular photosensitization reactions causing promutagenic oxidative DNA damage are involved in UVA genotoxicity

Exploring the sequence-function relationship in transcriptional regulation by the lac O1 operator.

Science.gov (United States)

Maity, Tuhin S; Jha, Ramesh K; Strauss, Charlie E M; Dunbar, John

2012-07-01

Understanding how binding of a transcription factor to an operator is influenced by the operator sequence is an ongoing quest. It facilitates discovery of alternative binding sites as well as tuning of transcriptional regulation. We investigated the behavior of the Escherichia coli Lac repressor (LacI) protein with a large set of lac O(1) operator variants. The 114 variants examined contained a mean of 2.9 (range 0-4) mutations at positions -4, -2, +2 and +4 in the minimally required 17 bp operator. The relative affinity of LacI for the operators was examined by quantifying expression of a GFP reporter gene and Rosetta structural modeling. The combinations of mutations in the operator sequence created a wide range of regulatory behaviors. We observed variations in the GFP fluorescent signal among the operator variants of more than an order of magnitude under both uninduced and induced conditions. We found that a single nucleotide change may result in changes of up to six- and 12-fold in uninduced and induced GFP signals, respectively. Among the four positions mutated, we found that nucleotide G at position -4 is strongly correlated with strong repression. By Rosetta modeling, we found a significant correlation between the calculated binding energy and the experimentally observed transcriptional repression strength for many operators. However, exceptions were also observed, underscoring the necessity for further improvement in biophysical models of protein-DNA interactions. © 2012 The Authors Journal compilation © 2012 FEBS.

Effector Overlap between the lac and mel Operons of Escherichia coli: Induction of the mel Operon with β-Galactosides.

Science.gov (United States)

Narang, Atul; Oehler, Stefan

2017-05-01

The lac (lactose) operon (which processes β-galactosides) and the mel (melibiose) operon (which processes α-galactosides) of Escherichia coli have a close historical connection. A number of shared substrates and effectors of the permeases and regulatory proteins have been reported over the years. Until now, β-thiogalactosides like TMG (methyl-β-d-thiogalactopyranoside) and IPTG (isopropyl-β-d-thiogalactopyranoside) have not generally been considered to be inducers of the mel operon. The same is true for β-galactosides such as lactose [β-d-galactopyranosyl-(1→4)-d-glucose], which is a substrate but is not itself an inducer of the lac operon. This report shows that all three sugars can induce the mel operon significantly when they are accumulated in the cell by Lac permease. Strong induction by β-thiogalactosides is observed in the presence of Lac permease, and strong induction by lactose (more than 200-fold) is observed in the absence of β-galactosidase. This finding calls for reevaluation of TMG uptake experiments as assays for Lac permease that were performed with mel + strains. IMPORTANCE The typical textbook picture of bacterial operons is that of stand-alone units of genetic information that perform, in a regulated manner, well-defined cellular functions. Less attention is given to the extensive interactions that can be found between operons. Well-described examples of such interactions are the effector molecules shared by the lac and mel operons. Here, we show that this set has to be extended to include β-galactosides, which have been, until now, considered not to effect the expression of the mel operon. That they can be inducers of the mel operon as well as the lac operon has not been noted in decades of research because of the Escherichia coli genetic background used in previous studies. Copyright © 2017 American Society for Microbiology.

76 FR 68124 - Television Broadcasting Services; Fond du Lac, WI

Science.gov (United States)

2011-11-03

... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [MB Docket No. 09-115, RM-11543; DA 11-1502] Television Broadcasting Services; Fond du Lac, WI AGENCY: Federal Communications Commission. ACTION: Proposed rule. SUMMARY: In this document, the Commission denies a petition for reconsideration of an August 12...

Influence of salt content and processing time on sensory characteristics of cooked "lacón".

Science.gov (United States)

Purriños, Laura; Bermúdez, Roberto; Temperán, Sara; Franco, Daniel; Carballo, Javier; Lorenzo, José M

2011-04-01

The influence of salt content and processing time on the sensory properties of cooked "lacón" were determined. "Lacón" is a traditional dry-cured and ripened meat product made in the north-west of Spain from the fore leg of the pig, following a similar process to that of dry-cured ham. Six batches of "lacón" were salted with different amounts of salt (LS (3 days of salting), MS (4 days of salting) and HS (5 days of salting)) and ripened during two times (56 and 84 days of dry-ripening). Cured odour in all batches studied, red colour and rancid odour in MS and HS batches, flavour intensity in MS batch and fat yellowness, rancid flavour and hardness in the HS batch were significantly different with respect to the time of processing. Appearance, odour, flavour and texture were not significantly affected by the salt content (P>0.05). However, the saltiness score showed significant differences with respect to the salt levels in all studied batches (56 and 84 days of process). The principal component analysis showed that physicochemical traits were the most important ones concerning the quality of dry-cured "lacón" and offered a good separation of the mean samples according to the dry ripening days and salt level. © 2010 The American Meat Science Association. Published by Elsevier Ltd. All rights reserved.

Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors

Science.gov (United States)

Ou, Hong-Yu; Kuang, Shan N.; He, Xinyi; Molgora, Brenda M.; Ewing, Peter J.; Deng, Zixin; Osby, Melanie; Chen, Wangxue; Xu, H. Howard

2015-01-01

Acinetobacter baumannii is an important human pathogen due to its multi-drug resistance. In this study, the genome of an ST10 outbreak A. baumannii isolate LAC-4 was completely sequenced to better understand its epidemiology, antibiotic resistance genetic determinants and potential virulence factors. Compared with 20 other complete genomes of A. baumannii, LAC-4 genome harbors at least 12 copies of five distinct insertion sequences. It contains 12 and 14 copies of two novel IS elements, ISAba25 and ISAba26, respectively. Additionally, three novel composite transposons were identified: Tn6250, Tn6251 and Tn6252, two of which contain resistance genes. The antibiotic resistance genetic determinants on the LAC-4 genome correlate well with observed antimicrobial susceptibility patterns. Moreover, twelve genomic islands (GI) were identified in LAC-4 genome. Among them, the 33.4-kb GI12 contains a large number of genes which constitute the K (capsule) locus. LAC-4 harbors several unique putative virulence factor loci. Furthermore, LAC-4 and all 19 other outbreak isolates were found to harbor a heme oxygenase gene (hemO)-containing gene cluster. The sequencing of the first complete genome of an ST10 A. baumannii clinical strain should accelerate our understanding of the epidemiology, mechanisms of resistance and virulence of A. baumannii. PMID:25728466

Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells.

Science.gov (United States)

Aoto, Kazushi; Sandell, Lisa L; Butler Tjaden, Naomi E; Yuen, Kobe C; Watt, Kristin E Noack; Black, Brian L; Durnin, Michael; Trainor, Paul A

2015-06-01

Neural crest cells (NCC) comprise a multipotent, migratory stem cell and progenitor population that gives rise to numerous cell and tissue types within a developing embryo, including craniofacial bone and cartilage, neurons and glia of the peripheral nervous system, and melanocytes within the skin. Here we describe two novel stable transgenic mouse lines suitable for lineage tracing and analysis of gene function in NCC. Firstly, using the F10N enhancer of the Mef2c gene (Mef2c-F10N) linked to LacZ, we generated transgenic mice (Mef2c-F10N-LacZ) that express LacZ in the majority, if not all migrating NCC that delaminate from the neural tube. Mef2c-F10N-LacZ then continues to be expressed primarily in neurogenic, gliogenic and melanocytic NCC and their derivatives, but not in ectomesenchymal derivatives. Secondly, we used the same Mef2c-F10N enhancer together with Cre recombinase to generate transgenic mice (Mef2c-F10N-Cre) that can be used to indelibly label, or alter gene function in, migrating NCC and their derivatives. At early stages of development, Mef2c-F10N-LacZ and Mef2c-F10N-Cre label NCC in a pattern similar to Wnt1-Cre mice, with the exception that Mef2c-F10N-LacZ and Mef2c-F10N-Cre specifically label NCC that have delaminated from the neural plate, while premigratory NCC are not labeled. Thus, our Mef2c-F10N-LacZ and Mef2c-F10N-Cre transgenic mice provide new resources for tracing migratory NCC and analyzing gene function in migrating and differentiating NCC independently of NCC formation. Copyright © 2015 Elsevier Inc. All rights reserved.

The REX survey as a tool to test the beaming model for BL Lacs

CERN Document Server

Caccianiga, A; MacCacaro, T; Wolter, A; Gioia, I M

1999-01-01

In the context of the beaming model (BM) BL Lac and FR I radio galaxies are thought to be the same class of sources seen at different angles. If this picture is correct, we expect to find some transition objects with intermediate properties between the two classes. To date, this intermediate population of objects is missing, probably due to the limiting fluxes of the current X-ray/radio surveys and/or to the criteria used to separate BL Lacs from normal elliptical galaxies. As pointed out by Browne and Marcha (1993), the detection of the transition objects requires particular attention since the "weak" BL Lac nucleus is hidden by the light of the host elliptical galaxy. A useful criterion often used to assess the presence of a non-thermal source, in addition to the stellar emission of the host galaxy, is the Ca contrast at 4000 AA (K/sub 4000/). This quantity, which is defined as the relative depression of the spectrum across 4000 AA, is a typical feature observed in a "normal" elliptical galaxy; the samples ...

Constraining the red shifts of TeV BL Lac objects

Science.gov (United States)

Qin, Longhua; Wang, Jiancheng; Yan, Dahai; Yang, Chuyuan; Yuan, Zunli; Zhou, Ming

2018-01-01

We present a model-dependent method to estimate the red shifts of three TeV BL Lac objects (BL Lacs) through fitting their (quasi-)simultaneous multi-waveband spectral energy distributions (SEDs) with a one-zone leptonic synchrotron self-Compton model. Considering the impact of electron energy distributions (EEDs) on the results, we use three types of EEDs to fit the SEDs: a power-law EED with exponential cut-off (PLC), a log-parabola (PLLP) EED and the broken power-law (BPL) EED. We also use a parameter α to describe the uncertainties of the extragalactic background light models, as in Abdo et al. We then use a Markov chain Monte Carlo method to explore the multi-dimensional parameter space and obtain the uncertainties of the model parameters based on the observational data. We apply our method to obtain the red shifts of three TeV BL Lac objects in the marginalized 68 per cent confidence, and find that the PLC EED does not fit the SEDs. For 3C66A, the red shift is 0.14-0.31 and 0.16-0.32 in the BPL and PLLP EEDs. For PKS1424+240, the red shift is 0.55-0.68 and 0.55-0.67 in the BPL and PLLP EEDs. For PG1553+113, the red shift is 0.22-0.48 and 0.22-0.39 in the BPL and PLLP EEDs. We also estimate the red shift of PKS1424+240 in the high stage to be 0.46-0.67 in the PLLP EED, roughly consistent with that in the low stage.

Infrared polarimetry and photometry of BL Lac objects

International Nuclear Information System (INIS)

Impey, C.D.; Williams, P.M.

1984-01-01

Photometry and polarimetry in the JHK wavebands have now been obtained for 25 BL Lac objects. Several new objects have been monitored for periods of up to five days, and accumulated data is sufficient for a statistical analysis of polarization properties. The selection effects operating on this sample are examined first. A power-law spectrum is consistent with the spectra of all but three objects. A number of important new results are reported. (author)

Inequalities in the dental health needs and access to dental services among looked after children in Scotland: a population data linkage study.

Science.gov (United States)

McMahon, Alex D; Elliott, Lawrie; Macpherson, Lorna Md; Sharpe, Katharine H; Connelly, Graham; Milligan, Ian; Wilson, Philip; Clark, David; King, Albert; Wood, Rachael; Conway, David I

2018-01-01

There is limited evidence on the health needs and service access among children and young people who are looked after by the state. The aim of this study was to compare dental treatment needs and access to dental services (as an exemplar of wider health and well-being concerns) among children and young people who are looked after with the general child population. Population data linkage study utilising national datasets of social work referrals for 'looked after' placements, the Scottish census of children in local authority schools, and national health service's dental health and service datasets. 633 204 children in publicly funded schools in Scotland during the academic year 2011/2012, of whom 10 927 (1.7%) were known to be looked after during that or a previous year (from 2007-2008). The children in the looked after children (LAC) group were more likely to have urgent dental treatment need at 5 years of age: 23%vs10% (n=209/16533), adjusted (for age, sex and area socioeconomic deprivation) OR 2.65 (95% CI 2.30 to 3.05); were less likely to attend a dentist regularly: 51%vs63% (n=5519/388934), 0.55 (0.53 to 0.58) and more likely to have teeth extracted under general anaesthesia: 9%vs5% (n=967/30253), 1.91 (1.78 to 2.04). LAC are more likely to have dental treatment needs and less likely to access dental services even when accounting for sociodemographic factors. Greater efforts are required to integrate child social and healthcare for LAC and to develop preventive care pathways on entering and throughout their time in the care system. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Transformation of lacZ using different promoters in the commercially ...

African Journals Online (AJOL)

Yomi

2012-01-26

Jan 26, 2012 ... forced growth under unnatural conditions. In order to ... yezoensis include the gluc, cat, GUS and GFP genes. (Cheney et al. ... bacterial lacZ gene encodes the β-galactosidase enzyme which is capable of .... Table 1. Effect of viral promoters on transient β-galactosidase activity in microparticle bombarded G.

ARCAS (ACACIA Regional Climate-data Access System) -- a Web Access System for Climate Model Data Access, Visualization and Comparison

Science.gov (United States)

Hakkarinen, C.; Brown, D.; Callahan, J.; hankin, S.; de Koningh, M.; Middleton-Link, D.; Wigley, T.

2001-05-01

A Web-based access system to climate model output data sets for intercomparison and analysis has been produced, using the NOAA-PMEL developed Live Access Server software as host server and Ferret as the data serving and visualization engine. Called ARCAS ("ACACIA Regional Climate-data Access System"), and publicly accessible at http://dataserver.ucar.edu/arcas, the site currently serves climate model outputs from runs of the NCAR Climate System Model for the 21st century, for Business as Usual and Stabilization of Greenhouse Gas Emission scenarios. Users can select, download, and graphically display single variables or comparisons of two variables from either or both of the CSM model runs, averaged for monthly, seasonal, or annual time resolutions. The time length of the averaging period, and the geographical domain for download and display, are fully selectable by the user. A variety of arithmetic operations on the data variables can be computed "on-the-fly", as defined by the user. Expansions of the user-selectable options for defining analysis options, and for accessing other DOD-compatible ("Distributed Ocean Data System-compatible") data sets, residing at locations other than the NCAR hardware server on which ARCAS operates, are planned for this year. These expansions are designed to allow users quick and easy-to-operate web-based access to the largest possible selection of climate model output data sets available throughout the world.

The Sedentary Multi-Frequency Survey. I. Statistical Identification and Cosmological Properties of HBL BL Lacs

OpenAIRE

Giommi, P.; Menna, M. T.; Padovani, P.

1999-01-01

We have assembled a multi-frequency database by cross-correlating the NVSS catalog of radio sources with the RASSBSC list of soft X-ray sources, obtaining optical magnitude estimates from the Palomar and UK Schmidt surveys as provided by the APM and COSMOS on-line services. By exploiting the nearly unique broad-band properties of High-Energy Peaked (HBL) BL Lacs we have statistically identified a sample of 218 objects that is expected to include about 85% of BL Lacs and that is therefore seve...

Hydrogeologic characteristics of domains of sparsely fractured rock in the granitic Lac Du Bonnet Batholith, southeastern Manitoba, Canada

International Nuclear Information System (INIS)

Stevenson, D.R.; Kozak, E.T.; Davison, C.C.; Gascoyne, M.; Broadfoot, R.A.

1996-06-01

The hydrogeologic characteristics of the granitic Lac du Bonnet batholith in southeastern Manitoba have been studied since 1978, as part of AECL's program to assess the concept of disposing of Canada's nuclear fuel waste deep within plutonic rocks of the Canadian Shield (Davison et al. 1994a). These studies have included an extensive program of drilling, logging, testing, sampling and monitoring in 19 deep surface boreholes drilled at Grid areas located across the Lac du Bonnet batholith, at the Whiteshell Laboratory (WL), and in surface and underground boreholes at the Underground Research Laboratory (URL). Based on these investigations domains of low permeability, sparsely fractured rock (SFR) have been identified in the Lac du Bonnet batholith

Induction of lacI- mutations in Escherichia coli cells after single and split-dose irradiation

International Nuclear Information System (INIS)

Kozubek, S.; Ryznar, L.

1992-01-01

In the lacI system of Escherichia coli, X-ray mutagenesis follows a linear-quadratic curve with suppression; the survival curve is exponential. Dose fractionation leads to nearly complete repair of premutational lesions during an incubation interval of 3.5 h. Repair starts with a delay of 1.5-2 h, suggesting the involvement of an inducible repair/mutation fixation system. The dose-dependence of mutagenesis is described by a simple model assuming two hits being required. A probable explanation might be that the premutagenic lesions consist of two closely spaced lesions on the opposite strands of the DNA molecule. (author)

[Fond du Lac archeological resources within the Draft Area Recommendation Report

International Nuclear Information System (INIS)

Danz, D.L.

1986-01-01

Research into archaeological resources of the Fond du Lac Band within the DOE proposed high-level nuclear waste sites resulted in the discovery of four traditional ancestral sites. A number of ancestral sites that are located within other proposed repository sites were also discovered

Access control and personal identification systems

CERN Document Server

Bowers, Dan M

1988-01-01

Access Control and Personal Identification Systems provides an education in the field of access control and personal identification systems, which is essential in selecting the appropriate equipment, dealing intelligently with vendors in purchases of the equipment, and integrating the equipment into a total effective system. Access control devices and systems comprise an important part of almost every security system, but are seldom the sole source of security. In order for the goals of the total system to be met, the other portions of the security system must also be well planned and executed

Radiocarbon measurements at LAC-UFF: Recent performance

Energy Technology Data Exchange (ETDEWEB)

Linares, Roberto, E-mail: rlinares@if.uff.br [Laboratório de Radiocarbono, Universidade Federal Fluminense, Av. Gal. Milton Tavares de Souza, s/n, Niterói 24230-346 (Brazil); Macario, Kita D. [Laboratório de Radiocarbono, Universidade Federal Fluminense, Av. Gal. Milton Tavares de Souza, s/n, Niterói 24230-346 (Brazil); Santos, Guaciara M. [Earth System Science, University of California, Irvine, B321 Croul Hall, Irvine, CA 92697-3100 (United States); Carvalho, Carla [Laboratório de Radiocarbono, Universidade Federal Fluminense, Av. Gal. Milton Tavares de Souza, s/n, Niterói 24230-346 (Brazil); Departamento de Geoquímica, Universidade Federal Fluminense, Outeiro São João Batista, s/n, Niterói 24020-141 (Brazil); Santos, Hellen C. dos; Gomes, Paulo R.S.; Castro, Maikel D.; Oliveira, Fabiana M.; Alves, Eduardo Q. [Laboratório de Radiocarbono, Universidade Federal Fluminense, Av. Gal. Milton Tavares de Souza, s/n, Niterói 24230-346 (Brazil)

2015-10-15

In 2012 a single stage accelerator mass spectrometer from NEC was installed at the Radiocarbon Laboratory of Universidade Federal Fluminense (LAC-UFF), Niterói, Brazil. Here, we present a status report of our facility. We discuss some modifications applied to our combustion protocol in an attempt to reduce our procedural blank, mostly to processed organic samples. Measurements of reference materials indicate low precision and accuracy that are partially related to beam optics through the acceleration tube. We observed that once the beam current intensity increases the measured {sup 13}C{sup +}/{sup 12}C{sup +} becomes erratic. Therefore, in order to maintain the AMS-δ{sup 13}C values within reasonable values, so that fractionation corrections using the spectrometer {sup 13}C{sup +}/{sup 12}C{sup +} values does not affect the final {sup 14}C results, we are forced to limit the {sup 12}C{sup −} beam intensity to ⩽30 μA. This requirement was confirmed during our accuracy tests, when measuring selected annual tree-rings wood samples from a Parana pine (Araucaria angustifolia) between 1927 and 1997 previously measured at the Keck Carbon Cycle AMS Facility (KCCAMS), at the University of California, Irvine (UCI). At the LAC-UFF tree-ring wood samples were processed and measured in 4 different batches during a period of about 5 months. The {sup 14}C results were later compared to the high-precision data obtained at KCCAMS/UCI and reached a good agreement. Recently a problem associated with graphitization yield were finally identified and new measurements with secondary standards are promising.

Effet des conditions climatiques sur le niveau du lac Sidi Ali (Moyen Atlas, Maroc)

OpenAIRE

Sayad, Ahmed; Chakiri, Saïd; Martin, Claude; Bejjaji, Zohra; Echarfaoui, Hassan

2012-01-01

Le lac Sidi Ali est un lac naturel d'altitude (2070-2080 m), sans exutoire superficiel, déterminé par le barrage d'une coulée basaltique. Doté d'un bassin versant apparent de 15,6 km2, il est alimenté par des eaux de ruissellement et par des sources karstiques. Son niveau subit des variations très fortes, annuelles et interannuelles, sous le contrôle des conditions climatiques, et en particulier des pluies et de l'évapotranspiration. Les périodes de sécheresse qui ont marqué les trois dernièr...

NEW HIGH- z FERMI BL LACS WITH THE PHOTOMETRIC DROPOUT TECHNIQUE

Energy Technology Data Exchange (ETDEWEB)

Kaur, A.; Ajello, M.; Hartmann, D. H.; Paliya, V. S. [Department of Physics and Astronomy, Clemson University, SC 29634-0978 (United States); Rau, A.; Greiner, J.; Bolmer, J.; Schady, P. [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstraße 1, D-85748 Garching (Germany); Domínguez, A., E-mail: akaur@g.clemson.edu [Grupo de Altas Energías, Universidad Complutense, E-28040 Madrid (Spain)

2017-01-01

Determining redshifts for BL Lacertae (BL Lac) objects using the traditional spectroscopic method is challenging due to the absence of strong emission lines in their optical spectra. We employ the photometric dropout technique to determine redshifts for this class of blazars using the combined 13 broadband filters from Swift -UVOT and the multi-channel imager GROND at the MPG 2.2 m telescope at ESO's La Silla Observatory. The wavelength range covered by these 13 filters extends from far-ultraviolet to the near-infrared. We report results on 40 new Fermi- detected BL Lacs with the photometric redshift determinations for five sources, with 3FGL J1918.2–4110 being the most distant in our sample at z  = 2.16. Reliable upper limits are provided for 20 sources in this sample. Using the highest energy photons for these Fermi -LAT sources, we evaluate the consistency with the gamma-ray horizon due to the extragalactic background light.

cas du lac Fetzara, région de Annaba

African Journals Online (AJOL)

ruissellement, elles acquièrent une nouvelle composition différente de celle des eaux de pluie. Les apports par les précipitations météoriques. Chaque mois pluvieux a fait l'objet d'une analyse chimique et une moyenne des concentrations des eaux apportées au lac a été estimée. La quantité des éléments apportés par.

Computing Optical Variable Periods of BL Lac Object S5 0716+ 714 ...

Indian Academy of Sciences (India)

Computing Optical Variable Periods of BL Lac Object S5 0716+ 714 ... The study of long-term periodical variation is an important way to get the charac- ... continuous Fourier transform together, define a window function, and finally obtain.

Study feature of variability extragalactic radio sources 3C 446 and BL Lac in the centimeter wavelength range

International Nuclear Information System (INIS)

Sukharev, A.L.

2015-01-01

This work presents the results of the analysis of long-term monitoring (over 40 years) changes in radio fluxes of the two extragalactic sources - 3C 446, and BL Lac. Observations at frequencies of 14.5, 8, 4.8 GHz were obtained in the Michigan Radio Astronomy Observatory (UMRAO). With using Fourier filtering were selected 0- C (short-period), and the trend component of flux variations that were analyzed separately with using the wavelet-analysis method. Each of these components is associated with certain physical processes in the 'core-accretion disk-jet' system. Were constructed time-frequency wavelet-spectra showing the changes of the frequency composition of the investigated data over time. For the trend component values of the main periods of -4-9 years (3C 446) and -8 years (BL Lac), for 0- C component -0.8-3 years (3C 446) and -0.6-4 years (BL Lac) and they appear in the temporal and structural changes of the jet. On the basis of calculating the global wavelet-spectra in the frequency range identified main phases activity of radio sources. Obtained comparison between the dynamics of jets (Mojave VLBI images), and change the frequency spectral structure of the studied data. With bandpass wavelet filtering, flux components corresponding to the main periods in the spectra, were identified and also found the delay between the observation frequencies in spectral bands of these periods

OGIS Access System

Data.gov (United States)

National Archives and Records Administration — The OGIS Access System (OAS) provides case management, stakeholder collaboration, and public communications activities including a web presence via a web portal.

Infrared polarimetry and photometry of BL Lac objects. 2

Energy Technology Data Exchange (ETDEWEB)

Impey, C D [Hawaii Univ., Honolulu (USA). Inst. for Astronomy; Brand, P W.J.L. [Edinburgh Univ. (UK). Dept. of Astronomy; Wolstencroft, R D [Royal Observatory, Edinburgh (UK); Williams, P M [United Kingdom Infrared Telescope Unit, Hilo, Hawaii (USA)

1984-07-15

Photometry and polarimetry in the JHK wavebands have now been obtained for 25 BL Lac objects. Several new objects have been monitored for periods of up to five days, and accumulated data is sufficient for a statistical analysis of polarization properties. The selection effects operating on this sample are examined first. A power-law spectrum is consistent with the spectra of all but three objects. A number of important new results are reported.

A source of artifact in the lacZ reversion assay in Escherichia coli.

Science.gov (United States)

Hoffmann, George R; Gray, Carol L; Lange, Paulina B; Marando, Christie I

2015-06-01

The lacZ reversion assay in Escherichia coli measures point mutations that occur by specific base substitutions and frameshift mutations. The tester strains cannot use lactose as a carbon source (Lac(-)), and revertants are easily detected by growth on lactose medium (Lac(+)). Six strains identify the six possible base substitutions, and five strains measure +G, -G, -CG, +A and -A frameshifts. Strong mutagens give dose-dependent increases in numbers of revertants per plate and revertant frequencies. Testing compounds that are arguably nonmutagens or weakly mutagenic, we often noted statistically significant dose-dependent increases in revertant frequency that were not accompanied by an absolute increase in numbers of revertants. The increase in frequency was wholly ascribable to a declining number of viable cells owing to toxicity. Analysis of the conditions revealed that the frequency of spontaneous revertants is higher when there are fewer viable cells per plate. The phenomenon resembles "adaptive" or "stress" mutagenesis, whereby lactose revertants accumulate in Lac(-) bacteria under starvation conditions in the absence of catabolite repression. Adaptive mutation is observed after long incubation and might be expected to be irrelevant in a standard assay using 48-h incubation. However, we found that elevated revertant frequencies occur under typical assay conditions when the bacterial lawn is thin, and this can cause increases in revertant frequency that mimic chemical mutagenesis when treatments are toxic but not mutagenic. Responses that resemble chemical mutagenesis were observed in the absence of mutagenic treatment in strains that revert by different frameshift mutations. The magnitude of the artifact is affected by cell density, dilution, culture age, incubation time, catabolite repression and the age and composition of media. Although the specific reversion assay is effective for quickly distinguishing classes of mutations induced by potent mutagens, its

Louisiana SIP: LAC 33:III Ch 2132. Stage II Vapor Recovery Systems for Control of Vehicle Refuelling Emissions at Gasoline Dispensing Facilities; SIP effective 2011-08-04 (LAd34) and 2016-02-29 (LAd47) to 2017-09-27

Science.gov (United States)

Louisiana SIP: LAC 33:III Ch 2132. Stage II Vapor Recovery Systems for Control of Vehicle Refuelling Emissions at Gasoline Dispensing Facilities; SIP effective 2011-08-04 (LAd34) and 2016-02-29 (LAd47) to 2017-09-27

Automated Computer Access Request System

Science.gov (United States)

Snook, Bryan E.

2010-01-01

The Automated Computer Access Request (AutoCAR) system is a Web-based account provisioning application that replaces the time-consuming paper-based computer-access request process at Johnson Space Center (JSC). Auto- CAR combines rules-based and role-based functionality in one application to provide a centralized system that is easily and widely accessible. The system features a work-flow engine that facilitates request routing, a user registration directory containing contact information and user metadata, an access request submission and tracking process, and a system administrator account management component. This provides full, end-to-end disposition approval chain accountability from the moment a request is submitted. By blending both rules-based and rolebased functionality, AutoCAR has the flexibility to route requests based on a user s nationality, JSC affiliation status, and other export-control requirements, while ensuring a user s request is addressed by either a primary or backup approver. All user accounts that are tracked in AutoCAR are recorded and mapped to the native operating system schema on the target platform where user accounts reside. This allows for future extensibility for supporting creation, deletion, and account management directly on the target platforms by way of AutoCAR. The system s directory-based lookup and day-today change analysis of directory information determines personnel moves, deletions, and additions, and automatically notifies a user via e-mail to revalidate his/her account access as a result of such changes. AutoCAR is a Microsoft classic active server page (ASP) application hosted on a Microsoft Internet Information Server (IIS).

Effect of the partial NaCl substitution by other chloride salts on the volatile profile during the ripening of dry-cured lacón

Energy Technology Data Exchange (ETDEWEB)

Dominguez, R.; Munekata, P.E.; Cittadini, A.; Lorenzo, J.M.

2016-07-01

The influence of three salting treatments (treatment II: 50% NaCl-50% KCl; III: 45% NaCl-25% KCl-20% CaCl2-10% MgCl2; IV: 30% NaCl-50% KCl-15% CaCl2-5% MgCl2) on the formation of volatile compounds throughout the process was studied and compared to those of a control “lacón” (treatment I: 100% NaCl). There was an intense formation of volatile compounds throughout the processing, particularly during the dry-ripening stage. The most abundant chemical family in all the formulations, in the final product was hydrocarbons followed by aldehydes. The total volatile compound release was more intense in the control “lacóns” (1164 AU×106 ·g–1dry matter) than in “lacóns” from formulations II, III and IV (817–891 AU×106 ·g−1dry matter). The “lacóns” from formulation I showed the highest amounts of aldehydes. The “lacóns” from formulations I and II presented the highest amounts of hydrocarbons. The main conclusion is that the replacement of NaCl produces changes in the volatile profile and could be affect the aroma of “lacón”. (Author)

Analyses de la dégradation du lac Kinkony pour la conservation du ...

African Journals Online (AJOL)

Le lac Kinkony fait partie des habitats clefs pour la biodiversité du Complexe des ... provide favoured habitat for numerous endemic and endangered avian, fish ... on fauna is essential for developing regional conservation and natural resource ...

X-ray emission from BL Lac objects: Comparison to the synchrotron self-Compton models

International Nuclear Information System (INIS)

Schwartz, D.A.; Madejski, G.; Ku, W.H.-M.

1982-01-01

As one part of our joint study of the X-ray properties of BL Lac objects, the authors compare the measured X-ray flux densities with those predicted using the synchrotron self-Compton (SSC) formalism (Jones et al. 1974). Naive application of the formalism predicts X-ray fluxes from 10 -3 to 10 5 those observed. They therefore ask what we can learn by simply assuming the SSC mechanism, and looking for ways to reconcile the observed and measured X-ray fluxes. This paper reports investigation of beaming factors due to relativistic ejection of a radiation source which is isotropic in its own rest frame. The authors conclude that large Lorentz factors, GAMMA approximately > 10, do not apply to BL Lac objects as a class. (Auth.)

A geological reconnaissance study of the Lac du Bonnet batholith

International Nuclear Information System (INIS)

Tammemagi, H.Y.; Kerford, P.S.; Requeima, J.C.; Temple, C.A.

1980-02-01

A geological reconnaissance survey was carried out of the Lac du Bonnet batholith, southeastern Manitoba, as part of the concept verification phase of the nuclear fuel waste disposal program for Canada. This report summarizes available geological information, presents the results of field mapping and discusses the geochemical analyses of rock samples. The geological and structural aspects of the batholith are described as well as its regional setting and possible genesis. (auth)

Kinetic Analysis of Lactose Exchange in Proteoliposomes Reconstituted with Purified lac Permease

NARCIS (Netherlands)

Lolkema, Julius S.; Carrasco, Nancy; Kaback, H. Ronald

1991-01-01

Lactose exchange catalyzed by purified lac permease reconstituted into proteoliposomes was analyzed with unequal concentrations of lactose on either side of the membrane and at low pH so as to prevent equilibration of the two pools. Exchange with external concentrations below 1.0 mM is a

Probing BL Lac and Cluster Evolution via a Wide-angle, Deep X-ray Selected Sample

Science.gov (United States)

Perlman, E.; Jones, L.; White, N.; Angelini, L.; Giommi, P.; McHardy, I.; Wegner, G.

1994-12-01

The WARPS survey (Wide-Angle ROSAT Pointed Survey) has been constructed from the archive of all public ROSAT PSPC observations, and is a subset of the WGACAT catalog. WARPS will include a complete sample of >= 100 BL Lacs at F_x >= 10(-13) erg s(-1) cm(-2) . A second selection technique will identify ~ 100 clusters at 0.15 = 0.304 +/- 0.062 for XBLs but = 0.60 +/- 0.05 for RBLs. Models of the X-ray luminosity function (XLF) are also poorly constrained. WARPS will allow us to compute an accurate XLF, decreasing the error bars above by over a factor of two. We will also test for low-luminosity BL Lacs, whose non-thermal nuclear sources are dim compared to the host galaxy. Browne and Marcha (1993) claim the EMSS missed most of these objects and is incomplete. If their predictions are correct, 20-40% of the BL Lacs we find will fall in this category, enabling us to probe the evolution and internal workings of BL Lacs at lower luminosities than ever before. By removing likely QSOs before optical spectroscopy, WARPS requires only modest amounts of telescope time. It will extend measurement of the cluster XLF both to higher redshifts (z>0.5) and lower luminosities (LX<1x10(44) erg s(-1) ) than previous measurements, confirming or rejecting the 3sigma detection of negative evolution found in the EMSS, and constraining Cold Dark Matter cosmologies. Faint NELGs are a recently discovered major contributor to the X-ray background. They are a mixture of Sy2s, starbursts and galaxies of unknown type. Detailed classification and evolution of their XLF will be determined for the first time.

Access control system for ISABELLE

International Nuclear Information System (INIS)

Potter, K.; Littenberg, L.

1977-01-01

An access system based on the one now in operation at the CERN ISR is recommended. Access doors would presumably be located at the entrances to the utility tunnels connecting the support buildings with the ring. Persons requesting access would insert an identity card into a scanner to activate the system. The request would be autologged, the keybank adjacent to the door would be unlocked and ISABELLE operations would be notified. The operator would then select the door, activating a TV-audio link. The person requesting entry would draw a key from the bank, show it and his film badge to the operator who would enable the door release

Easy Access: Auditing the System Network

Science.gov (United States)

Wiech, Dean

2013-01-01

In today's electronic learning environment, access to appropriate systems and data is of the utmost importance to students, faculty, and staff. Without proper access to the school's internal systems, teachers could be prevented from logging on to an online learning system and students might be unable to submit course work to an online…

Distinct roles of two ceramide synthases, CaLag1p and CaLac1p, in the morphogenesis of Candida albicans

DEFF Research Database (Denmark)

Cheon, Seon Ah; Bal, Jyotiranjan; Song, Yunkyoung

2012-01-01

p) and Lac1p (CaLac1p) are functionally distinct. Lack of CaLag1p, but not CaLac1p, caused severe defects in the growth and hyphal morphogenesis of C. albicans. Deletion of CaLAG1 decreased expression of the hypha-specific HWP1 and ECE1 genes. Moreover, overexpression of CaLAG1 induced pseudohyphal...... growth in this organism under non-hypha-inducing conditions, suggesting that CaLag1p is necessary for relaying signals to induce hypha-specific gene expression. Analysis of ceramide and sphingolipid composition revealed that CaLag1p predominantly synthesizes ceramides with C24:0/C26:0 fatty acid moieties...

Optical polarimetry of quasi-stellar and BL Lac objects

International Nuclear Information System (INIS)

Wills, D.; Wills, B.J.; Breger, M.; Hsu, J.

1980-01-01

We report observations of 39 extragalactic objects, using a new polarimeter at McDonald Observatory. Most of the observations were made in January and June 1980. Some new BL Lac objects were found, and some of the previously known members of this class were also observed. Polarization exceeding 3--4 times the formal rms uncertainties was found in about ten QSO's. Rapid changes of polarization and/or position angle occurred in some of the BL Lacertae objects, usually with <0.1-mag change in the total light

Evaluation of critical indicators in the process of acquiring supplies and services LAC-UFPE

Science.gov (United States)

Caetano, V. F.; Ferreira, C. V.; dos Santos, M. J.; Honorato, F. A.

2015-01-01

In laboratories linked to public universities and accredited by the NBR ISO/IEC 17025, to meet efficiently item 4.6 (procurement of supplies and services) is a challenge that can be accomplished by programming based on historical purchases and services. In this study, we evaluated the critical procurement items to meet the quality management system of the LAC-UFPE: reagents, certified reference material, of equipment parts, maintenance and calibration of equipment and instruments. It was found that the most critical item is the certified reference material, the purchase or repair of which must be expedited within 125 days prior to the receipt to occur within the desired period.

The extent of co-metabolism of glucose and galactose by L. lactis changes with the expression of the lacSZ operon from Streptococcus thermophilus

DEFF Research Database (Denmark)

Solem, Christian; Købmann, Brian Jensen; Jensen, Peter Ruhdal

2008-01-01

The lactose transporter and β-galactosidase from Streptococcus thermophilus, encoded by the lacSZ operon, were introduced into the lactose-negative strain Lactococcus lactis MG1363 and the expression of the lacSZ operon was modulated by substitution of the native promoter with randomized synthetic...... promoters. A series of strains with various expression levels of lacSZ were examined for their fermentation of lactose. Strains with a high expression level were found to metabolize lactose in a similar manner to S. thermophilus, i.e. the galactose moiety of lactose was excreted to the growth medium...... and only glucose was metabolized in glycolysis. Interestingly, strains with low expression of the operon showed a mixed acid metabolism and co-metabolism of galactose and glucose. The lactose flux increased gradually with increasing expression of the lacSZ operon until an optimum was observed...

Dissemination in athymic nude mice of lacZ transfected small cell lung cancer cells identified by X-gal staining

DEFF Research Database (Denmark)

Rømer, M U; Christiansen, J; Brünner, N

1995-01-01

The small cell lung cancer cell lines GLC-2 and DMS 456 were genetically labeled with the lacZ gene and examined for invasive and metastatic potential in META/Bom nude mice. The lacZ gene encodes the enzyme beta-D- galactosidase, and cells expressing this enzyme were identified by staining...... with the chromogenic substrate X-gal. lacZ expressing cells were investigated after subcutaneous (s.c.) inoculation and intravenous (i.v.) injection. The X-gal detection of beta-D-galactosidase activity proved to be a rapid and easy means for specific and highly sensitive identification of metastases. All primary s.......c. tumors stained by X-gal. The primary tumors of GLC-2 regularly demonstrated local invasive growth and produced multiple metastases in several organs. In contrast, primary DMS 456 tumors only occasionally demonstrated local invasion and very rarely generated secondary foci. No experimental metastases were...

Absorption in the spectra of quasi stellar objects and BL Lac objects

International Nuclear Information System (INIS)

Perry, J.J.; Burbidge, E.M.; Burbidge, G.R.

1978-06-01

An extensive review is given of the observations of absorption in the spectra of QSOs and BL Lac objects. In Table Ia we summarize all of the information available up to May 1, 1978 on objects which show absorption. Following discussion of the observations in Section II, possible interpretations are critically discussed. (orig.) [de

Mutagenicity of the peroxisome proliferators clofibrate, Wyeth 14,643 and di-2-ethylhexyl phthalate in the lacZ plasmid-based transgenic mouse mutation assay

Directory of Open Access Journals (Sweden)

Boerrigter Michaël

2004-01-01

Full Text Available Abstract Background Peroxisome proliferators are considered rodent carcinogens that are putative human non-carcinogens based on the presumed absence of direct genetic toxicity in rodent and human cells and the resistance of human cells to the induction of peroxisomes by peroxisome proliferators. The highly sensitive lacZ plasmid-based transgenic mouse mutation assay was employed to investigate the mutagenicity of several peroxisome proliferators based on several lines of evidence suggesting that these agents may in fact exert a genotoxic effect. Methods Male and female lacZ-plasmid based transgenic mice were treated at 4 months of age with 6 doses of 2,333 mg di-2-ethylhexyl phthalate (DHEP, 200 mg Wyeth-14,643, or 90 mg clofibrate per kg of bodyweight, respectively, over a two-week period. Control animals were treated with the respective vehicles only (35% propyl glycol for DEHP and Wyeth-14,643 treatment controls and sterile water for clofibrate treatment controls. The mutant frequency in liver, kidney and spleen DNA was determined as the proportion of retrieved mutant and wild-type lacZ plasmids expressed in Escherichia Coli C host cells employing a positive selection system for mutant plasmids. Results Exposure to DEHP or Wyeth-14,643 significantly increased the mutant frequency in liver, but not in kidney or spleen, of both female and male mice. Treatment with clofibrate did not lead to an increased mutant frequency in any of the organs studied. Conclusion The results indicate that some peroxisome proliferators display an organ-specific mutagenicity in lacZ plasmid-based transgenic mice consistent with historical observations of organ- and compound-specific carcinogenicity.

Generation and evaluation of an IPTG-regulated version of Vav-gene promoter for mouse transgenesis.

Directory of Open Access Journals (Sweden)

Francesca Grespi

2011-03-01

Full Text Available Different bacteria-derived systems for regulatable gene expression have been developed for the use in mammalian cells and some were also successfully adopted for in vivo use in vertebrate model organisms. However, certain limitations apply to most of these systems, including leakiness of transgene expression, inefficient transgene silencing or activation, as well as limited tissue accessibility of transgene-inducers or their unfavourable pharmacokinetics. In this study, we evaluated the suitability of the lac-operon/lac-repressor (lacO/lacI system for the regulation of the well-established Vav-gene promoter that allows inducible transgene expression in different haematopoietic lineages in mice. Using the fluorescence marker protein Venus as a reporter, we observed that the lacO/lacI system could be amended to modulate transgene-expression in haematopoietic cells. However, reporter expression was not uniform and the lacO elements introduced into the Vav-gene promoter only conferred limited repression and reversion of lacI-mediated gene silencing after administration of IPTG. Although further optimization of the system is required, the lacO-modified version of the Vav-gene promoter may be adopted as a tool where low basal gene-expression and limited transient induction of protein expression are desired, e.g. for the activation of oncogenes or transgenes that act in a dominant-negative manner.

LANSCE personnel access control system (PACS)

International Nuclear Information System (INIS)

Sturrock, J.C.; Gallegos, F.R.; Hall, M.J.

1997-01-01

The Radiation Security System (RSS) at the Los Alamos Neutron Science Center (LANSCE) provides personnel protection from prompt radiation due to accelerated beam. The Personnel Access Control System (PACS) is a component of the RSS that is designed to prevent personnel access to areas where prompt radiation is a hazard. PACS was designed to replace several older personnel safety systems (PSS) with a single modem unified design. Lessons learned from the operation over the last 20 years were incorporated into a redundant sensor, single-point failure safe, fault tolerant, and tamper-resistant system that prevents access to the beam areas by controlling the access keys and beam stoppers. PACS uses a layered philosophy to the physical and electronic design. The most critical assemblies are battery backed up, relay logic circuits; less critical devices use Programmable Logic Controllers (PLCs) for timing functions and communications. Outside reviewers have reviewed the operational safety of the design. The design philosophy, lessons learned, hardware design, software design, operation, and limitations of the device are described

Computing Optical Variable Periods of BL Lac Object S5 0716+714 ...

Indian Academy of Sciences (India)

2016-01-27

Jan 27, 2016 ... From a large volume of literature, we have collected effective observation of BL Lac object S5 0716+714 in the optical band, and constructed its long-term light curve from 1994 to 2006 AD. The light curve shows that S5 0716+714 is very active and exhibits very complicated non-sinusoidal variations.

Internet-accessible real-time weather information system

Digital Repository Service at National Institute of Oceanography (India)

Desai, R.G.P.; Joseph, A.; Desa, E.; Mehra, P.; Desa, E.; Gouveia, A.D.

An internet-accessible real-time weather information system has been developed. This system provides real-time accessibility to weather information from a multitude of spatially distributed weather stations. The Internet connectivity also offers...

Access Control Management for SCADA Systems

Science.gov (United States)

Hong, Seng-Phil; Ahn, Gail-Joon; Xu, Wenjuan

The information technology revolution has transformed all aspects of our society including critical infrastructures and led a significant shift from their old and disparate business models based on proprietary and legacy environments to more open and consolidated ones. Supervisory Control and Data Acquisition (SCADA) systems have been widely used not only for industrial processes but also for some experimental facilities. Due to the nature of open environments, managing SCADA systems should meet various security requirements since system administrators need to deal with a large number of entities and functions involved in critical infrastructures. In this paper, we identify necessary access control requirements in SCADA systems and articulate access control policies for the simulated SCADA systems. We also attempt to analyze and realize those requirements and policies in the context of role-based access control that is suitable for simplifying administrative tasks in large scale enterprises.

Computer access security code system

Science.gov (United States)

Collins, Earl R., Jr. (Inventor)

1990-01-01

A security code system for controlling access to computer and computer-controlled entry situations comprises a plurality of subsets of alpha-numeric characters disposed in random order in matrices of at least two dimensions forming theoretical rectangles, cubes, etc., such that when access is desired, at least one pair of previously unused character subsets not found in the same row or column of the matrix is chosen at random and transmitted by the computer. The proper response to gain access is transmittal of subsets which complete the rectangle, and/or a parallelepiped whose opposite corners were defined by first groups of code. Once used, subsets are not used again to absolutely defeat unauthorized access by eavesdropping, and the like.

Using the Markov chain Monte Carlo method to study the physical properties of GeV-TeV BL Lac objects

Science.gov (United States)

Qin, Longhua; Wang, Jiancheng; Yang, Chuyuan; Yuan, Zunli; Mao, Jirong; Kang, Shiju

2018-01-01

We fit the spectral energy distributions (SEDs) of 46 GeV-TeV BL Lac objects in the frame of leptonic one-zone synchrotron self-Compton (SSC) model and investigate the physical properties of these objects. We use the Markov chain Monte Carlo (MCMC) method to obtain the basic parameters, such as magnetic field (B), the break energy of the relativistic electron distribution (γ ^' }b), and the electron energy spectral index. Based on the modeling results, we support the following scenarios for GeV-TeV BL Lac objects. (1) Some sources have large Doppler factors, implying other radiation mechanism should be considered. (2) Compared with flat spectrum quasars (FSRQs), GeV-TeV BL Lac objects have weaker magnetic fields and larger Doppler factors, which cause the ineffective cooling and shift the SEDs to higher bands. Their jet powers are around 4.0 × 1045 erg s-1, compared with radiation power, 5.0 × 1042 erg s-1, indicating that only a small fraction of jet power is transformed into the emission power. (3) For some BL Lacs with large Doppler factors, their jet components could have two substructures, e.g., the fast core and the slow sheath. For most GeV-TeV BL Lacs, Kelvin-Helmholtz instabilities are suppressed by their higher magnetic fields, leading to micro-variability or intro-day variability in the optical bands. (4) Combined with a sample of FSRQs, an anti-correlation between the peak luminosity, Lpk, and the peak frequency, νpk, is obtained, favoring the blazar sequence scenario. In addition, an anti-correlation between the jet power, Pjet, and the break Lorentz factor, γb, also supports the blazar sequence.

Discovery of Intermediates of lacZ β-Galactosidase Catalyzed Hydrolysis Using dDNP NMR

DEFF Research Database (Denmark)

Kjeldsen, Christian; Ardenkjær-Larsen, Jan Henrik; Duus, Jens Ø.

2018-01-01

Using dissolution dynamic nuclear polarization, the sensitivity of single scan solution state 13C NMR can be improved up to 4 orders of magnitude. In this study, the enzyme lacZ β-galactosidase from Escherichia coli was subjected to hyperpolarized substrate, and previously unknown reaction...

Discovery of Intermediates of lacZ beta-Galactosidase Catalyzed Hydrolysis Using dDNP NMR

DEFF Research Database (Denmark)

Kjeldsen, Christian; Ardenkjær-Larsen, Jan Henrik; Duus, Jens Øllgaard

2018-01-01

Using dissolution dynamic nuclear polarization, the sensitivity of single scan solution state C-13 NMR can be improved up to 4 orders of magnitude. In this study, the enzyme lacZ beta-galactosidase from Escherichia coli was subjected to hyperpolarized substrate, and previously unknown reaction...

Research of user access control for networked manufacturing system

Institute of Scientific and Technical Information of China (English)

ZHENG Xiao-lin; LEI Yu; CHEN De-ren

2006-01-01

An integrated user access control method was proposed to address the issues of security and management in networked manufacturing systems (NMS).Based on the analysis of the security issues in networked manufacturing system,an integrated user access control method composed of role-based access control (RBAC),task-based access control (TBAC),relationship-driven access control (RDAC)and coalition-based access control (CBAC) was proposed,including the hierarchical user relationship model,the reference model and the process model.The elements and their relationships were defined,and the expressions of constraints authorization were given.The extensible access control markup language (XACML) was used to implement this method.This method was used in the networked manufacturing system in the Shaoxing spinning region of China.The results show that the integrated user access control method can reduce the costs of system security maintenance and management.

lacZ transduced human breast cancer xenografts as an in vivo model for the study of invasion and metastasis

DEFF Research Database (Denmark)

Brünner, N; Thompson, E W; Spang-Thomsen, M

1992-01-01

in the animals by usual histological procedures would require extensive sectioning of the whole animal. To overcome this problem, we transduced human breast cancer cells with a replication-defective Moloney murine leukaemia retroviral vector (M-MuLV) containing both neoR (neomycin resistance) and lacZ genes...... but not the surrounding mouse tissue on either whole tissue blocks or histological sections. The staining procedure was highly sensitive, allowing detection of microfoci of human cancer cells, and quantitative estimation of the metastatic capacity of the cells. These results indicate that lacZ transduction of human...

Computer Security Systems Enable Access.

Science.gov (United States)

Riggen, Gary

1989-01-01

A good security system enables access and protects information from damage or tampering, but the most important aspects of a security system aren't technical. A security procedures manual addresses the human element of computer security. (MLW)

The genus Hypostomus Lacépède, 1803, and its Surinam representatives (Siluriformes, Loricariidae)

NARCIS (Netherlands)

Boeseman, M.

1968-01-01

CONTENTS Introduction................... 3 The generic name................. 4 The type species of Hypostomus Lacépède.......... 6 The identity of Acipenser plecostomus Linnaeus........ 9 The distribution and habitats of the Surinam species........ 12 The relationship of the Surinam

An Attribute Based Access Control Framework for Healthcare System

Science.gov (United States)

Afshar, Majid; Samet, Saeed; Hu, Ting

2018-01-01

Nowadays, access control is an indispensable part of the Personal Health Record and supplies for its confidentiality by enforcing policies and rules to ensure that only authorized users gain access to requested resources in the system. In other words, the access control means protecting patient privacy in healthcare systems. Attribute-Based Access Control (ABAC) is a new access control model that can be used instead of other traditional types of access control such as Discretionary Access Control, Mandatory Access Control, and Role-Based Access Control. During last five years ABAC has shown some applications in both recent academic fields and industry purposes. ABAC by using user’s attributes and resources, makes a decision according to an access request. In this paper, we propose an ABAC framework for healthcare system. We use the engine of ABAC for rendering and enforcing healthcare policies. Moreover, we handle emergency situations in this framework.

A new access scheme in OFDMA systems

Institute of Scientific and Technical Information of China (English)

GU Xue-lin; YAN Wei; TIAN Hui; ZHANG Ping

2006-01-01

This article presents a dynamic random access scheme for orthogonal frequency division multiple access (OFDMA) systems. The key features of the proposed scheme are:it is a combination of both the distributed and the centralized schemes, it can accommodate several delay sensitivity classes,and it can adjust the number of random access channels in a media access control (MAC) frame and the access probability according to the outcome of Mobile Terminals access attempts in previous MAC frames. For floating populated packet-based networks, the proposed scheme possibly leads to high average user satisfaction.

Information-flow-based Access Control for Virtualized Systems

Directory of Open Access Journals (Sweden)

Dmitriy Aleksandrovich Postoev

2014-12-01

Full Text Available The article is devoted to the method of information-flow-based access control, adopted for virtualized systems. General structure of access control system for virtual infrastructure is proposed.

Observations of low and intermediate-frequency-peaked BL Lacs above 100 GeV with VERITAS

Directory of Open Access Journals (Sweden)

Errando M.

2013-12-01

Full Text Available Most of the ~ 50 blazars detected to date at TeV energies (E > 0.1 TeV are high-frequency-peaked BL Lacs (HBLs. Only a handful episodic detections of low- and intermediate-frequency-peaked BL Lacs (LBL/IBLs, with synchrotron peak frequencies in the infrared and optical regime have been reported by ground-based gamma-ray telescopes, typically during high-flux states. The VERITAS array located in southern Arizona has observed five known TeV LBL/IBLs since 2009: 3C 66A, WComae, PKS 1424+240, S5 0716+714 and BL Lacertae, with exposures of 5-10 hours/year, which so far resulted in the detection of a bright, sub-hour timescale gamma-ray flare of BL Lacertae in June 2011. We also report the detection and characterization of two new IBLs: VER J0521+211 and B2 1215+30.

Dynamical Black Hole Masses of BL Lac Objects from the Sloan Digital Sky Survey

NARCIS (Netherlands)

Plotkin, Richard M.; Markoff, Sera; Trager, Scott C.; Anderson, Scott F.

2012-01-01

We measure black hole masses for 71 BL Lac objects from the Sloan Digital Sky Survey (SDSS) with redshifts out to z ∼ 0.4. We perform spectral decompositions of their nuclei from their host galaxies and measure their stellar velocity dispersions. Black hole masses are then derived from the black

The LAC Test: A New Look at Auditory Conceptualization and Literacy Development K-12.

Science.gov (United States)

Lindamood, Charles; And Others

The Lindamood Auditory Conceptualization (LAC) Test was constructed with the recognition that the process of decoding involves an integration of the auditory, visual, and motor senses. Requiring the manipulation of colored blocks to indicate conceptualization of test patterns spoken by the examiner, subtest 1 entails coding of identity, number,…

Caractérisation des sables et morphologie du fond du lac du ...

African Journals Online (AJOL)

Une analyse sédimentologique et minéralogique réalisée sur un cycle hydrologique entre octobre 2004 et août 2005 a permis d\\'évaluer les charges solides en suspension et de caractériser les sédiments du lac du barrage de Taabo. La concentration moyenne en matières en suspension (12 mg.L-1) et la turbidité ...

Caractérisation des sables et morphologie du fond du lac du ...

African Journals Online (AJOL)

Administrateur

Une analyse sédimentologique et minéralogique réalisée sur un cycle hydrologique entre octobre 2004 et août 2005 a permis d'évaluer les charges solides en suspension et de caractériser les sédiments du lac du barrage de Taabo. La concentration moyenne en matières en suspension (12 mg.L-1) et la turbidité ...

Effect of the partial NaCl substitution by other chloride salts on the volatile profile during the ripening of dry-cured lacón

Directory of Open Access Journals (Sweden)

Domínguez, R.

2016-06-01

Full Text Available The influence of three salting treatments (treatment II: 50% NaCl-50% KCl; III: 45% NaCl-25% KCl-20% CaCl2-10% MgCl2; IV: 30% NaCl-50% KCl-15% CaCl2-5% MgCl2 on the formation of volatile compounds throughout the process was studied and compared to those of a control “lacón” (treatment I: 100% NaCl. There was an intense formation of volatile compounds throughout the processing, particularly during the dry-ripening stage. The most abundant chemical family in all the formulations, in the final product was hydrocarbons followed by aldehydes. The total volatile compound release was more intense in the control “lacóns” (1164 AU_106·g-1dry matter than in “lacóns” from formulations II, III and IV (817-891 AUx106·g-1dry matter. The “lacóns” from formulation I showed the highest amounts of aldehydes. The “lacóns” from formulations I and II presented the highest amounts of hydrocarbons. The main conclusion is that the replacement of NaCl produces changes in the volatile profile and could be affect the aroma of “lacón”.Se estudió la influencia de tres tratamientos de salado (tratamiento II: 50 % NaCl-50 % KCl; III: 45 % NaCl-25 % KCl-20 % CaCl2-10 % MgCl2; IV: 30 % NaCl-50 % KCl-15 % CaCl2-5 % MgCl2 en la formación de compuestos volátiles durante la elaboración de lacón, en comparación con un control (tratamiento I: 100 % NaCl. Hubo una intensa formación de compuestos volátiles durante el procesado, principalmente durante la fase de secado-maduración. La familia química más abundante en el producto final fueron los hidrocarbonos, seguidos por los aldehídos. La liberación de volátiles fue más intensa en los lacones control (1164 AU_106·g-1 materia seca que en los otros lacones (817-891 AUx106· g-1 materia seca. Los lacones de la formulación I mostraron las mayores cantidades de aldehídos, y los lacones de las formulaciones I y II presentaron los mayores contenidos de hidrocarburos. La principal conclusi

Du Lac de Geneve au Lac Baikal: deux metropoles en construction

Directory of Open Access Journals (Sweden)

Guy Mettan

2006-08-01

Full Text Available En apparence, Geneve et Irkutsk n'ont rien en commun. A part une amitie reciproque et la proximite d'un lac, il est difficile de trouver des points communs entre la Suisse francophone, dont Geneve est la ville le plus importante, et la Siberie centrale, dont Irkutsk, est la capitale. Et pourtant les deux regions, malgre les differences de taille, de densite de la population, de climat, d'economie et de traditions culturelles, sont confrontees au meme probleme: elles sont trop petites et trop limitees pour assurer, avec leurs seuls moyens, leur avenir et elles doivent imperativement s'unir a des villes voisines pour renforcer leur statut de metropole regionale et s'imposer face aux regions et aux pays concurrents.C'est ainsi qu'Irkutsk projette de s'unir aux villes voisines d'Angarsk et de Chelekhov pour constituer une megapole au c?ur de la Siberie, tandis qu'a Geneve le debat fait rage pour trouver des solutions a l'exiguite geographique et a l'insuffisance des moyens face aux grandes regions metropolitaines de France, d'Italie et d'Allemagne.Ce debat est propre a toute la Suisse. Malgre sa petitesse, la Suisse est divisee en 26 cantons. Ces unites administratives sont jugees trop couteuses, trop petites, trop lourdes et trop compliquees pour assurer l'avenir economique et meme politique du pays. De nombreux groupes de reflexion proposent donc de reduire ce nombre a 3, 5 ou 10 grandes provinces selon les cas. En Suisse, romande, il y a dix ans, des mouvements politiques ont meme lance l'idee de fusionner les cantons de Vaud (dont Lausanne est la capitale et de Geneve. Mais l'echec a ete fracassant : le peuple des deux cantons a refuse cette option a 80% des voix. On cherche donc d'autres solutions.Les discussions s'orientent desormais autour de la constitution d'une grande metropole lemanique qui regrouperait les deux grandes villes de Geneve et Lausanne et les villes plus petites de Montreux, Vevey, Nyon ainsi que la ville francaise d

Jet Precession Driven by a Supermassive Black Hole Binary System in the BL Lac Object PG 1553+113

Science.gov (United States)

Caproni, Anderson; Abraham, Zulema; Motter, Juliana Cristina; Monteiro, Hektor

2017-12-01

The recent discovery of a roughly simultaneous periodic variability in the light curves of the BL Lac object PG 1553+113 at several electromagnetic bands represents the first case of such odd behavior reported in the literature. Motivated by this, we analyzed 15 GHz interferometric maps of the parsec-scale radio jet of PG 1553+113 to verify the presence of a possible counterpart of this periodic variability. We used the Cross-entropy statistical technique to obtain the structural parameters of the Gaussian components present in the radio maps of this source. We kinematically identified seven jet components formed coincidentally with flare-like features seen in the γ-ray light curve. From the derived jet component positions in the sky plane and their kinematics (ejection epochs, proper motions, and sky position angles), we modeled their temporal changes in terms of a relativistic jet that is steadily precessing in time. Our results indicate a precession period in the observer’s reference frame of 2.24 ± 0.03 years, compatible with the periodicity detected in the light curves of PG 1553+113. However, the maxima of the jet Doppler boosting factor are systematically delayed relative to the peaks of the main γ-ray flares. We propose two scenarios that could explain this delay, both based on the existence of a supermassive black hole binary system in PG 1553+113. We estimated the characteristics of this putative binary system that also would be responsible for driving the inferred jet precession.

Nuclear information access system

International Nuclear Information System (INIS)

Ham, C. H.; Yang, M. H.; Yoon, S. W.

1998-01-01

The energy supply in the countries, which have abundant energy resources, may not be affected by accepting the assertion of anti-nuclear and environment groups. Anti-nuclear movements in the countries which have little energy resources may cause serious problem in securing energy supply. Especially, it is distinct in Korea because she heavily depends on nuclear energy in electricity supply(nuclear share in total electricity supply is about 40%).The cause of social trouble surrounding nuclear energy is being involved with various circumstances. However, it is very important that we are not aware of the importance of information access and prepared for such a situation from the early stage of nuclear energy's development. In those matter, this paper analyzes the contents of nuclear information access system in France and Japan which have dynamic nuclear development program and presents the direction of the nuclear access regime through comparing Korean status and referring to progresses of the regime

Role Based Access Control system in the ATLAS experiment

International Nuclear Information System (INIS)

Valsan, M L; Dumitru, I; Darlea, G L; Bujor, F; Dobson, M; Miotto, G Lehmann; Schlenker, S; Avolio, G; Scannicchio, D A; Filimonov, V; Khomoutnikov, V; Zaytsev, A S; Korol, A A; Bogdantchikov, A; Caramarcu, C; Ballestrero, S; Twomey, M

2011-01-01

The complexity of the ATLAS experiment motivated the deployment of an integrated Access Control System in order to guarantee safe and optimal access for a large number of users to the various software and hardware resources. Such an integrated system was foreseen since the design of the infrastructure and is now central to the operations model. In order to cope with the ever growing needs of restricting access to all resources used within the experiment, the Roles Based Access Control (RBAC) previously developed has been extended and improved. The paper starts with a short presentation of the RBAC design, implementation and the changes made to the system to allow the management and usage of roles to control access to the vast and diverse set of resources. The RBAC implementation uses a directory service based on Lightweight Directory Access Protocol to store the users (∼3000), roles (∼320), groups (∼80) and access policies. The information is kept in sync with various other databases and directory services: human resources, central CERN IT, CERN Active Directory and the Access Control Database used by DCS. The paper concludes with a detailed description of the integration across all areas of the system.

New Light Curves and Analysis of the Overcontact Binaries PP Lac and DK Sge

Science.gov (United States)

Sanders, S. J.; Hargis, J. R.; Bradstreet, D. H.

2004-12-01

As a by-product of the ongoing work with the Catalog and AtLas of Eclipsing Binaries database (CALEB; Bradstreet et al. 2004), several hundred eclipsing binary systems have been identified that have either unpublished or poor quality light curves. We present new V & Rc light curves for the overcontact systems PP Lac and DK Sge, both chosen because their deep eclipses (peak-to-peak amplitudes of nearly 0.7 mag) help constrain the light curve modelling. Data were obtained using the 41-cm telescope at the Eastern University Observatory equipped with an SBIG ST-10XME CCD. PP Lac (P= 0.40116 d) is a W-type contact binary with only one previously published light curve (Dumont & Maraziti 1990), but the data are sparse and almost non-existent at primary eclipse. Modelling of these data gave varying results; the published mass ratios differ by nearly 0.3. Our data confirms the noted differing eclipse depths but we find the primary eclipse to be total. We present a new light curve solution using Binary Maker 3 (Bradstreet & Steelman 2002) and Wilson-Devinney, finding the mass ratio to be well-constrained by the duration of total eclipse. A period study will be presented using previously existing and newly derived times of minimum light. DK Sge (P=0.62182 d) appears to be an A-type contact binary with no published light curve. The eclipses are partial, with the primary eclipse being deeper by about 0.08 mag. The maxima show evidence of a slight asymmetry, although the light curve appears to be repeatable over the 1 month of observations. We present the first light curve solution using Binary Maker 3 and Wilson-Devinney, but have limited mass ratio constraints due to the absence of radial velocity data. A period study will be presented using previously existing and newly derived times of minimum light.

Local gene regulation details a recognition code within the LacI transcriptional factor family.

Directory of Open Access Journals (Sweden)

Francisco M Camas

2010-11-01

Full Text Available The specific binding of regulatory proteins to DNA sequences exhibits no clear patterns of association between amino acids (AAs and nucleotides (NTs. This complexity of protein-DNA interactions raises the question of whether a simple set of wide-coverage recognition rules can ever be identified. Here, we analyzed this issue using the extensive LacI family of transcriptional factors (TFs. We searched for recognition patterns by introducing a new approach to phylogenetic footprinting, based on the pervasive presence of local regulation in prokaryotic transcriptional networks. We identified a set of specificity correlations--determined by two AAs of the TFs and two NTs in the binding sites--that is conserved throughout a dominant subgroup within the family regardless of the evolutionary distance, and that act as a relatively consistent recognition code. The proposed rules are confirmed with data of previous experimental studies and by events of convergent evolution in the phylogenetic tree. The presence of a code emphasizes the stable structural context of the LacI family, while defining a precise blueprint to reprogram TF specificity with many practical applications.

Role Based Access Control system in the ATLAS experiment

CERN Document Server

Valsan, M L; The ATLAS collaboration; Lehmann Miotto, G; Scannicchio, D A; Schlenker, S; Filimonov, V; Khomoutnikov, V; Dumitru, I; Zaytsev, A S; Korol, A A; Bogdantchikov, A; Caramarcu, C; Ballestrero, S; Darlea, G L; Twomey, M; Bujor, F; Avolio, G

2011-01-01

The complexity of the ATLAS experiment motivated the deployment of an integrated Access Control System in order to guarantee safe and optimal access for a large number of users to the various software and hardware resources. Such an integrated system was foreseen since the design of the infrastructure and is now central to the operations model. In order to cope with the ever growing needs of restricting access to all resources used within the experiment, the Roles Based Access Control (RBAC) previously developed has been extended and improved. The paper starts with a short presentation of the RBAC design, implementation and the changes made to the system to allow the management and usage of roles to control access to the vast and diverse set of resources. The paper continues with a detailed description of the integration across all areas of the system: local Linux and Windows nodes in the ATLAS Control Network (ATCN), the Linux application gateways offering remote access inside ATCN, the Windows Terminal Serv...

Role Based Access Control System in the ATLAS Experiment

CERN Document Server

Valsan, M L; The ATLAS collaboration; Lehmann Miotto, G; Scannicchio, D A; Schlenker, S; Filimonov, V; Khomoutnikov, V; Dumitru, I; Zaytsev, A S; Korol, A A; Bogdantchikov, A; Avolio, G; Caramarcu, C; Ballestrero, S; Darlea, G L; Twomey, M; Bujor, F

2010-01-01

The complexity of the ATLAS experiment motivated the deployment of an integrated Access Control System in order to guarantee safe and optimal access for a large number of users to the various software and hardware resources. Such an integrated system was foreseen since the design of the infrastructure and is now central to the operations model. In order to cope with the ever growing needs of restricting access to all resources used within the experiment, the Roles Based Access Control (RBAC) previously developed has been extended and improved. The paper starts with a short presentation of the RBAC design, implementation and the changes made to the system to allow the management and usage of roles to control access to the vast and diverse set of resources. The paper continues with a detailed description of the integration across all areas of the system: local Linux and Windows nodes in the ATLAS Control Network (ATCN), the Linux application gateways offering remote access inside ATCN, the Windows Terminal Serv...

Archive of Geosample Data and Information from the University of Minnesota National Lacustrine Core Repository (LacCore)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The National Lacustrine Core Repository (LacCore), operated by the University of Minnesota is a partner in the Index to Marine and Lacustrine Geological Samples...

Dating fractures and fracture movement in the Lac du Bonnet Batholith

International Nuclear Information System (INIS)

Gascoyne, M.; Brown, A.; Ejeckam, R.B.; Everitt, R.A.

1997-04-01

This report examines and summarizes all work that has been done from 1980 to the present in determining the age of rock crystallization, fracture initiation, fracture reactivation and rates of fracture movement in the Lac du Bonnet Batholith to provide information for Atomic Energy of Canada Limited's (AECL) Canadian Nuclear Fuel Waste Management Program. Geological and petrographical indicators of relative age (e.g. cross-cutting relationships, sequences of fracture infilling minerals, P-T characteristics of primary and secondary minerals) are calibrated with radiometric age determinations on minerals and whole rock samples, using 87 Rb- 87 Sr, 40 K- 39 Ar, 40 Ar- 39 Ar and fission track methods. Most fractures and fracture zones inclined at low angles are found to be ancient features, first formed in the Early Proterozoic under conditions of deuteric alteration. Following some movement on fractures in the Late Proterozoic and Early Paleozoic, reactivation of fractures during the Pleistocene is established from uranium-series dating methods and use of stable isotopic contents of fracture infilling minerals (mainly calcite). Some indication of movement on fracture zones during the Pleistocene is given by electron spin resonance dating techniques on fault gouge. The slow rate of propagation of fractures is indicated by mineral infillings, their P-T characteristics and U-series calcite ages in a fracture in sparsely fractured rock, accessible from AECL's Underground Research Laboratory. These results collectively indicate that deep fractures observed in the batholith are ancient features and the fracturing and jointing in the upper 200 m is relatively recent (< 1 Ma) and largely a result of stress release. (author)

Analysis of Access Control Policies in Operating Systems

Science.gov (United States)

Chen, Hong

2009-01-01

Operating systems rely heavily on access control mechanisms to achieve security goals and defend against remote and local attacks. The complexities of modern access control mechanisms and the scale of policy configurations are often overwhelming to system administrators and software developers. Therefore, mis-configurations are common, and the…

Performance estimates for personnel access control systems

International Nuclear Information System (INIS)

Bradley, R.G.

1980-10-01

Current performance estimates for personnel access control systems use estimates of Type I and Type II verification errors. A system performance equation which addresses normal operation, the insider, and outside adversary attack is developed. Examination of this equation reveals the inadequacy of classical Type I and II error evaluations which require detailed knowledge of the adversary threat scenario for each specific installation. Consequently, new performance measures which are consistent with the performance equation and independent of the threat are developed as an aid in selecting personnel access control systems

The NuSTAR view on Hard-TeV BL Lacs

Science.gov (United States)

Costamante, L.; Bonnoli, G.; Tavecchio, F.; Ghisellini, G.; Tagliaferri, G.; Khangulyan, D.

2018-05-01

Hard-TeV BL Lacs are a new type of blazars characterized by a hard intrinsic TeV spectrum, locating the peak of their gamma-ray emission in the spectral energy distribution (SED) above 2-10 TeV. Such high energies are problematic for the Compton emission, using a standard one-zone leptonic model. We study six examples of this new type of BL Lacs in the hard X-ray band with NuSTAR. Together with simultaneous observations with the Neil Gehrels Swift Observatory, we fully constrain the peak of the synchrotron emission in their SED, and test the leptonic synchrotron self-Compton (SSC) model. We confirm the extreme nature of 5 objects also in the synchrotron emission. We do not find evidence of additional emission components in the hard X-ray band. We find that a one-zone SSC model can in principle reproduce the extreme properties of both peaks in the SED, from X-ray up to TeV energies, but at the cost of i) extreme electron energies with very low radiative efficiency, ii) conditions heavily out of equipartition (by 3 to 5 orders of magnitude), and iii) not accounting for the simultaneous UV data, which then should belong to a different emission component, possibly the same as the far-IR (WISE) data. We find evidence of this separation of the UV and X-ray emission in at least two objects. In any case, the TeV electrons must not "see" the UV or lower-energy photons, even if coming from different zones/populations, or the increased radiative cooling would steepen the VHE spectrum.

Access control within military C4ISR systems

Science.gov (United States)

Maschino, Mike

2003-07-01

Command, Control, Communications, Computers, Intelligence, Surveillance and Reconnaissance (C4ISR) tactical battlefield systems must provide the right information and resources to the right individuals at the right time. At the same time, the C4ISR system must enforce access controls to prevent the wrong individuals from obtaining sensitive information, or consuming scarce resources. Because lives, missions and property depend upon them, these access control mechanisms must be effective, reliable, efficient and flexible. The mechanisms employed must suit the nature of the items that are to be protected, as well as the varieties of access policies that must be enforced, and the types of access that will be made to these items. Some access control technologies are inherently centralized, while others are suitable for distributed implementation. The C4ISR architect must select from among the available technologies a combination of mechanisms that eases the burden of policy administration, but is inherently survivable, accurate, resource efficient, and which provides low latency. This paper explores various alternative access enforcement mechanisms, and assesses their effectiveness in managing policy-driven access control within the battlespace.

Quasi-simultaneous observations of BL Lac object Mrk 501 in X-ray, UV, visible, IR, and radio frequencies

International Nuclear Information System (INIS)

Kondo, Y.; Worrall, D.M.; Mushotzky, R.F.; Hackney, R.L.; Hackney, K.R.H.; Oke, J.B.; Yee, H.K.C.; Neugebauer, G.; Matthews, K.; Feldman, P.A.; Brown, R.L.

1981-01-01

Quasi-simultaneous observations of the BL Lac object Mrk 501 were performed for the first time at X-ray, ultraviolet, visible infrared, and radio frequencies. As the BL Lac objects are known to vary in their flux, such a ''quasi-instantaneous'' spectral energy profile is necessary in order to describe properly the energy generation mechanism. The observed spectral slope from the X-ray to UV regions is positive and continuous, but that from the mid-UV to visible light region becomes gradually flat and possibly turns down toward lower frequencies; the optical-radio emission cannot be accounted for by a single power law. Several theoretical models have been considered for the emission mechanism. In some cases quantitative comparison with the data is not practical. However, most of the models are, at least, not inconsistent with the observations. A quantitative comparison has been peformed with the synchroton self-Compton model; the total spectrum is found consistent with this model. The spectrum from visible light to X-ray is consistent with synchrotron radiation or with inverse-Compton scattering by a hot thermal cloud of electrons. The continuity of the spectral slope from X-ray to UV implied by the current data suggests that the previous estimates of the total luminosity of this BL Lac object has been underestimated by a factor of about 3 or 4

Données préliminaires sur la diversité du zooplancton du lac Nokoué

African Journals Online (AJOL)

SARAH

31 juil. 2017 ... contribuera davantage à la compréhension de la dynamique de cette communauté biologique du lac. Mots clés ... dans une perspective de gestion durable de la .... ramenés au Laboratoire de Contrôle de Qualité des Eaux.

Safety testing for LHC access system

CERN Document Server

Valentini, F; Ninin, P; Scibile, S

2008-01-01

In the domain of Safety Real-Time Systems the problem of testing represents always a big effort in terms of time, costs and efficiency to guarantee an adequate coverage degree. Exhaustive tests may, in fact, not be practicable for large and distributed systems. This paper describes the testing process followed during the validation of the CERN's LHC Access System [1], responsible for monitoring and preventing physical risks for the personnel accessing the underground areas. In the paper we also present a novel strategy for the testing problem, intended to drastically reduce the time for the test patterns generation and execution. In particular, we propose a methodology for blackbox testing that relies on the application of Model Checking techniques. Model Checking is a formal method from computer science, commonly adopted to prove correctness of system’s models through an automatic system’s state space exploration against some property formulas.

A 400-year phytolith-based reconstruction of wild rice (Zizania palustris) abundance from Mud Lake core sediments, Fond du Lac Band of Lake Superior Chippewa Reservation, Minnesota, USA.

Science.gov (United States)

Munoz, R.; Caylor, E.; Yost, C. L.; Drake, C.; Ladwig, J. L.; Myrbo, A.; Howes, T.

2014-12-01

Wild rice (Zizania palustris L.) is an aquatic grass with spiritual and subsistence significance to Native people of the Great Lakes region of North America. Mud Lake (Mashkiigwaagamaag), located on the Fond du Lac Band of Lake Superior Chippewa Reservation in Carlton County, Minnesota, USA, once supported an extensive population of wild rice (manoomin). However, early 20th century attempts to ditch and drain surrounding wetlands for landuse intensification severely altered the natural hydrological system that supports wild rice. Fond du Lac Resource Management (FDLRM) technicians are currently working to increase the wild rice population in Mud Lake. As part of these efforts, this phytolith study was undertaken to better understand how wild rice abundance has fluctuated over the past 400 years, with particular emphasis on the 19th and 20th centuries. Phytoliths are microscopic opal silica plant remains that are incorporated into soils and lake sediments after the plant-parts that contain them decay. Wild rice produces phytolith morphotypes that are unequivocally diagnostic. Mud Lake core MNMN-MUD11-1C-1P-1 (46°43'38.39"N, 92°42'2.45"W) was piston cored by LacCore (National Lacustrine Core Facility) and FDLRM technicians on 24 May 2011. Initial core descriptions, multi-sensor core logging, phytolith sampling and phytolith extractions were completed during the summer of 2014 at LacCore. Wild rice phytolith identification and quantification was conducted on twelve samples using brightfield microscopy at 400x magnification. Wild rice phytolith concentration values ranged from 68 to 2,300 phytoliths/cm3. Wild rice accumulation rates ranged from 9 to 383 phytoliths/ cm2/yr, peaking in 1952 AD. Wild rice abundance in Mud Lake appears to be influenced by a complex set of variables that include anthropogenic disturbance, climatic events and aquatic plant community succession.

Effect Through Broadcasting System Access Point For Video Transmission

Directory of Open Access Journals (Sweden)

Leni Marlina

2015-08-01

Full Text Available Most universities are already implementing wired and wireless network that is used to access integrated information systems and the Internet. At present it is important to do research on the influence of the broadcasting system through the access point for video transmitter learning in the university area. At every university computer network through the access point must also use the cable in its implementation. These networks require cables that will connect and transmit data from one computer to another computer. While wireless networks of computers connected through radio waves. This research will be a test or assessment of how the influence of the network using the WLAN access point for video broadcasting means learning from the server to the client. Instructional video broadcasting from the server to the client via the access point will be used for video broadcasting means of learning. This study aims to understand how to build a wireless network by using an access point. It also builds a computer server as instructional videos supporting software that can be used for video server that will be emitted by broadcasting via the access point and establish a system of transmitting video from the server to the client via the access point.

Access safety systems - New concepts from the LHC experience

International Nuclear Information System (INIS)

Ladzinski, T.; Delamare, C.; Luca, S. di; Hakulinen, T.; Hammouti, L.; Havart, F.; Juget, J.F.; Ninin, P.; Nunes, R.; Riesco, T.; Sanchez-Corral Mena, E.; Valentini, F.

2012-01-01

The LHC Access Safety System has introduced a number of new concepts into the domain of personnel protection at CERN. These can be grouped into several categories: organisational, architectural and concerning the end-user experience. By anchoring the project on the solid foundations of the IEC 61508/61511 methodology, the CERN team and its contractors managed to design, develop, test and commission on time a SIL3 safety system. The system uses a successful combination of the latest Siemens redundant safety programmable logic controllers with a traditional relay logic hard wired loop. The external envelope barriers used in the LHC include personnel and material access devices, which are interlocked door-booths introducing increased automation of individual access control, thus removing the strain from the operators. These devices ensure the inviolability of the controlled zones by users not holding the required credentials. To this end they are equipped with personnel presence detectors and the access control includes a state of the art bio-metry check. Building on the LHC experience, new projects targeting the refurbishment of the existing access safety infrastructure in the injector chain have started. This paper summarises the new concepts introduced in the LHC access control and safety systems, discusses the return of experience and outlines the main guiding principles for the renewal stage of the personnel protection systems in the LHC injector chain in a homogeneous manner. (authors)

Effet des conditions climatiques sur le niveau du lac Sidi Ali (Moyen Atlas, Maroc

Directory of Open Access Journals (Sweden)

Claude Martin

2011-11-01

Full Text Available Le lac Sidi Ali est un lac naturel d'altitude (2070-2080 m, sans exutoire superficiel, déterminé par le barrage d'une coulée basaltique. Doté d'un bassin versant apparent de 15,6 km2, il est alimenté par des eaux de ruissellement et par des sources karstiques. Son niveau subit des variations très fortes, annuelles et interannuelles, sous le contrôle des conditions climatiques, et en particulier des pluies et de l'évapotranspiration. Les périodes de sécheresse qui ont marqué les trois dernières décennies, se sont traduites par un abaissement du niveau de près de 7 m. Mais les précipitations abondantes des années 2008-09 et 2009-10 ont provoqué une nette remontée. Une régression multiple d'assez bonne qualité (r = 0,87 lie la variation annuelle du niveau (d'août à août à différents paramètres (conditions climatiques et niveau initial du lac.Lake Sidi Ali is a natural lake at high altitude (2070-2080 m, without surface outlet, determined by the dam of a basalt flow. With an apparent catchment of 15.6 km2, it is fed by runoff and karst springs. Its level shows strong annual and interannual variations, depending on weather conditions, particularly rainfall and evapotranspiration. Droughts that have marked the last three decades have resulted in a lowering of about 7 m of the water level. But heavy rainfall that occurred in 2008-09 and 2009-10 caused a marked rise. A multiple regression of sufficient quality (r = 0.87 binds the annual change (from august to august at differents parameters (weather conditions and initial level of the lake.

Task-role-based Access Control Model in Smart Health-care System

Directory of Open Access Journals (Sweden)

Wang Peng

2015-01-01

Full Text Available As the development of computer science and smart health-care technology, there is a trend for patients to enjoy medical care at home. Taking enormous users in the Smart Health-care System into consideration, access control is an important issue. Traditional access control models, discretionary access control, mandatory access control, and role-based access control, do not properly reflect the characteristics of Smart Health-care System. This paper proposes an advanced access control model for the medical health-care environment, task-role-based access control model, which overcomes the disadvantages of traditional access control models. The task-role-based access control (T-RBAC model introduces a task concept, dividing tasks into four categories. It also supports supervision role hierarchy. T-RBAC is a proper access control model for Smart Health-care System, and it improves the management of access rights. This paper also proposes an implementation of T-RBAC, a binary two-key-lock pair access control scheme using prime factorization.

Task Delegation Based Access Control Models for Workflow Systems

Science.gov (United States)

Gaaloul, Khaled; Charoy, François

e-Government organisations are facilitated and conducted using workflow management systems. Role-based access control (RBAC) is recognised as an efficient access control model for large organisations. The application of RBAC in workflow systems cannot, however, grant permissions to users dynamically while business processes are being executed. We currently observe a move away from predefined strict workflow modelling towards approaches supporting flexibility on the organisational level. One specific approach is that of task delegation. Task delegation is a mechanism that supports organisational flexibility, and ensures delegation of authority in access control systems. In this paper, we propose a Task-oriented Access Control (TAC) model based on RBAC to address these requirements. We aim to reason about task from organisational perspectives and resources perspectives to analyse and specify authorisation constraints. Moreover, we present a fine grained access control protocol to support delegation based on the TAC model.

Integrated Identity and Access Management System for Tertiary ...

African Journals Online (AJOL)

Nigerian Journal of Technology ... identity management and access control and the unavailability of actionable information on pattern of ... This Tertiary Identity and Access Management System (T-IAMS) is a fingerprint biometric database that ...

UV spectrum of the BL Lac object PKS 0521-36

Energy Technology Data Exchange (ETDEWEB)

Danziger, I.J. (European Southern Observatory, Garching (Germany, F.R.)); Bergeron, J. (Centre National de la Recherche Scientifique, 75 - Paris (France). Inst. d' Astrophysique); Fosbury, R.A.E. (Royal Greenwich Observatory, Hailsham (UK)); Maraschi, L.; Treves, A. (Consiglio Nazionale delle Ricerche, Milan (Italy). Lab. di Fisica Cosmica; Milan Univ. (Italy). Ist. di Fisica); Tanzi, E.G. (Consiglio Nazionale delle Ricerche, Milan (Italy). Lab. di Fisica Cosmica)

1983-05-01

Ultraviolet observations (1200 to 3000 A) with the IUE satellite of the BL Lac object PKS 0521-36 are presented. The only emission line which appears clearly in the spectrum is Ly..cap alpha.., which is asymmetric with a component displaced approx. 3000 km s/sup -1/ to the red. The intensity of the line and the upper limits on other lines are compared with the model calculations on QSOs and Seyfert nuclei by Kwan and Krolik. The continuous energy distribution is discussed, combining non-simultaneous observations from the ultraviolet to the infrared. The spectral range of the non-thermal source from far IR to far UV can be described by a single power law of index -1.5.

Northern hemisphere mid-latitude geomagnetic anomaly revealed from Levantine Archaeomagnetic Compilation (LAC).

Science.gov (United States)

Shaar, R.; Tauxe, L.; Agnon, A.; Ben-Yosef, E.; Hassul, E.

2015-12-01

The rich archaeological heritage of Israel and nearby Levantine countries provides a unique opportunity for archaeomagnetic investigation in high resolution. Here we present a summary of our ongoing effort to reconstruct geomagnetic variations of the past several millennia in the Levant at decadal to millennial resolution. This effort at the Southern Levant, namely the "Levantine Archaeomagnetic Compilation" (LAC), presently consists of data from over 650 well-dated archaeological objects including pottery, slag, ovens, and furnaces. In this talk we review the methodological challenges in achieving a robust master secular variation curve with realistic error estimations from a large number of different datasets. We present the current status of the compilation, including the southern and western Levant LAC data (Israel, Cyprus, and Jordan) and other published north-eastern Levant data (Syria and southern Turkey), and outline the main findings emerging from these data. The main feature apparent from the new compilation is an extraordinary intensity high that developed over the Levant region during the first two millennia BCE. The climax of this event is a double peak intensity maximum starting at ca. 1000 BCE and ending at ca. 735 BCE, accompanied with at least two events of geomagnetic spikes. Paleomagnetic directions from this period demonstrate anomalies of up to 20 degrees far from the averaged GAD field. This leads us to postulate that the maximum in the intensity is a manifestation of an intense mid-latitude local positive geomagnetic anomaly that persisted for over two centuries.

Task-role-based Access Control Model in Smart Health-care System

OpenAIRE

Wang Peng; Jiang Lingyun

2015-01-01

As the development of computer science and smart health-care technology, there is a trend for patients to enjoy medical care at home. Taking enormous users in the Smart Health-care System into consideration, access control is an important issue. Traditional access control models, discretionary access control, mandatory access control, and role-based access control, do not properly reflect the characteristics of Smart Health-care System. This paper proposes an advanced access control model for...

Fish communities in man-made lakes = Peuplements ichtyologiques des lacs de barrage

OpenAIRE

Jackson, P.N.B.; Marshall, B.E.; Paugy, Didier

1988-01-01

Il existe actuellement des réservoirs artificiels sur de nombreuses rivières africaines. Leur construction a modifié les conditions écologiques (facteurs édaphiques, apports en éléments nutritifs) et changé la composition des peuplements ichtyologiques ... Le barrage lui-même peut être un obstacle pour des poissons tels que les anguilles ou les mulets migrants depuis la mer et entraîner la disparition des espèces en amont ... Les lacs de barrage ont une vaste zone pélagique favorable au déve...

Évaluation du niveau de pollution par les métaux lourds des lacs ...

African Journals Online (AJOL)

La présente étude a pour objectif principal d'évaluer le niveau de pollution métallique des lacs Bini et Dang (Ngaoundéré, Cameroun) à travers l'analyse des eaux et des sédiments de surface. La concentration des métaux lourds (Ni, Cr, Fe, Pb, Cd, Zn) a été mesurée par spectrophotométrie d'absorption atomique.

Residues in the H+ Translocation Site Define the pKa for Sugar Binding to LacY†

Science.gov (United States)

Smirnova, Irina; Kasho, Vladimir; Sugihara, Junichi; Choe, Jun-Yong; Kaback, H. Ronald

2009-01-01

A remarkably high pKa of approximately 10.5 has been determined for sugar-binding affinity to the lactose permease of Escherichia coli (LacY), indicating that, under physiological conditions, substrate binds to fully protonated LacY. We have now systematically tested site-directed replacements for the residues involved in sugar binding, as well as H+ translocation and coupling, in order to determine which residues may be responsible for this alkaline pKa. Mutations in the sugar-binding site (Glu126, Trp151, Glu269) markedly decrease affinity for sugar but do not alter the pKa for binding. In contrast, replacements for residues involved in H+ translocation (Arg302, Tyr236, His322, Asp240, Glu325, Lys319) exhibit pKa values for sugar binding that are either shifted toward neutral pH or independent of pH. Values for the apparent dissociation constant for sugar binding (Kdapp) increase greatly for all mutants except neutral replacements for Glu325 or Lys319, which are characterized by remarkably high affinity sugar binding (i.e., low Kdapp) from pH 5.5 to pH 11. The pH dependence of the on- and off-rate constants for sugar binding measured directly by stopped-flow fluorometry implicates koff as a major factor for the affinity change at alkaline pH and confirms the effects of pH on Kdapp inferred from steady-state fluorometry. These results indicate that the high pKa for sugar binding by wild-type LacY cannot be ascribed to any single amino acid residue but appears to reside within a complex of residues involved in H+ translocation. There is structural evidence for water bound in this complex, and the water could be the site of protonation responsible for the pH dependence of sugar binding. PMID:19689129

77 FR 27245 - Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN

Science.gov (United States)

2012-05-09

... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R3-R-2012-N069; FXRS1265030000S3-123-FF03R06000] Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN AGENCY: Fish and... plan (CCP) and environmental assessment (EA) for Big Stone National Wildlife Refuge (Refuge, NWR) for...

An Analysis of Periodic Components in BL Lac Object S5 0716 +714 with MUSIC Method

Science.gov (United States)

Tang, J.

2012-01-01

Multiple signal classification (MUSIC) algorithms are introduced to the estimation of the period of variation of BL Lac objects.The principle of MUSIC spectral analysis method and theoretical analysis of the resolution of frequency spectrum using analog signals are included. From a lot of literatures, we have collected a lot of effective observation data of BL Lac object S5 0716 + 714 in V, R, I bands from 1994 to 2008. The light variation periods of S5 0716 +714 are obtained by means of the MUSIC spectral analysis method and periodogram spectral analysis method. There exist two major periods: (3.33±0.08) years and (1.24±0.01) years for all bands. The estimation of the period of variation of the algorithm based on the MUSIC spectral analysis method is compared with that of the algorithm based on the periodogram spectral analysis method. It is a super-resolution algorithm with small data length, and could be used to detect the period of variation of weak signals.

H1DS: A new web-based data access system

Energy Technology Data Exchange (ETDEWEB)

Pretty, D.G., E-mail: david.pretty@anu.edu.au; Blackwell, B.D.

2014-05-15

Highlights: • We present H1DS, a new RESTful web service for accessing fusion data. • We examine the scalability and extensibility of H1DS. • We present a fast and user friendly web browser client for the H1DS web service. • A summary relational database is presented as an application of the H1DS API. - Abstract: A new data access system, H1DS, has been developed and deployed for the H-1 Heliac at the Australian Plasma Fusion Research Facility. The data system provides access to fusion data via a RESTful web service. With the URL acting as the API to the data system, H1DS provides a scalable and extensible framework which is intuitive to new users, and allows access from any internet connected device. The H1DS framework, originally designed to work with MDSplus, has a modular design which can be extended to provide access to alternative data storage systems.

H1DS: A new web-based data access system

International Nuclear Information System (INIS)

Pretty, D.G.; Blackwell, B.D.

2014-01-01

Highlights: • We present H1DS, a new RESTful web service for accessing fusion data. • We examine the scalability and extensibility of H1DS. • We present a fast and user friendly web browser client for the H1DS web service. • A summary relational database is presented as an application of the H1DS API. - Abstract: A new data access system, H1DS, has been developed and deployed for the H-1 Heliac at the Australian Plasma Fusion Research Facility. The data system provides access to fusion data via a RESTful web service. With the URL acting as the API to the data system, H1DS provides a scalable and extensible framework which is intuitive to new users, and allows access from any internet connected device. The H1DS framework, originally designed to work with MDSplus, has a modular design which can be extended to provide access to alternative data storage systems

Characterisation and discrimination of various types of lac resin using gas chromatography mass spectrometry techniques with quaternary ammonium reagents.

Science.gov (United States)

Sutherland, K; del Río, J C

2014-04-18

A variety of lac resin samples obtained from artists' suppliers, industrial manufacturers, and museum collections were analysed using gas chromatography mass spectrometry (GCMS) and reactive pyrolysis GCMS with quaternary ammonium reagents. These techniques allowed a detailed chemical characterisation of microgram-sized samples, based on the detection and identification of derivatives of the hydroxy aliphatic and cyclic (sesquiterpene) acids that compose the resin. Differences in composition could be related to the nature of the resin, e.g. wax-containing (unrefined), bleached, or aged samples. Furthermore, differences in the relative abundances of aliphatic hydroxyacids appear to be associated with the biological source of the resin. The diagnostic value of newly characterised lac components, including 8-hydroxyacids, is discussed here for the first time. Identification of derivatised components was aided by AMDIS deconvolution software, and discrimination of samples was enhanced by statistical evaluation of data using principal component analysis. The robustness of the analyses, together with the minimal sample size required, make these very powerful approaches for the characterisation of lac resin in museum objects. The value of such analyses for enhancing the understanding of museum collections is illustrated by two case studies of objects in the collection of the Philadelphia Museum of Art: a restorer's varnish on a painting by Luca Signorelli, and a pictorial inlay in an early nineteenth-century High Chest by George Dyer. Copyright © 2014 Elsevier B.V. All rights reserved.

Human engineering considerations in designing a computerized controlled access security system

International Nuclear Information System (INIS)

Moore, J.W.; Banks, W.W.

1988-01-01

This paper describes a human engineering effort in the design of a major security system upgrade at Lawrence Livermore National Laboratory. This upgrade was to be accomplished by replacing obsolete and difficult-to-man (i.e., multiple operator task actions required) security equipment and systems with a new, automated, computer-based access control system. The initial task was to assist the electronic and mechanical engineering staff in designing a computerized security access system too functionally and ergonomically accommodate 100% of the Laboratory user population. The new computerized access system was intended to control entry into sensitive exclusion areas by requiring personnel to use an entry booth-based system and/or a remote access control panel system. The primary user interface with the system was through a control panel containing a magnetic card reader, function buttons, LCD display, and push-button keypad

Lac du Flambeau Band of Lake Superior Chippewa Indians Strategic Energy Plan

Energy Technology Data Exchange (ETDEWEB)

Bryan Hoover

2009-11-16

This plan discusses the current energy use on the Lac du Flambeau Reservation, the current status of the Tribe's energy program, as well as the issues and concerns with energy on the reservation. This plan also identifies and outlines energy opportunities, goals, and objectives for the Tribe to accomplish. The overall goal of this plan is to address the energy situation of the reservation in a holistic manner for the maximum benefit to the Tribe. This plan is an evolving document that will be re-evaluated as the Tribe's energy situation changes.

Search for relation between flares and photometric variability outside of flares in EV Lac

International Nuclear Information System (INIS)

Rojzman, G.Sh.

1984-01-01

The observations of the flare star EV Lac in July-September 1981 have confirmed the existence of photometric variability outside the flares during the night. It was found that, as a rule, a slow increase of brightness in U and B bands during 1-2 hours preceded the flares. It is suggested that the variability outside the flares is the result of the variability of chpomospheric emission lines and continuum that are emitted by the chromospheric preflare formations

REPEUPLEMENTS EN ALEVINS NOURRIS ET DÉMOGRAPHIE DE LA POPULATION DE TRUITE (SALMO TRUTTA L. DANS LE REDON, UN AFFLUENT DU LAC LÉMAN INTERROMPU PAR UN OBSTACLE

Directory of Open Access Journals (Sweden)

CHAMPIGNEULLE A.

2003-01-01

Full Text Available La démographie d’une population de truite (Salmo trutta L. a été étudiée, dans un contexte de repeuplements en alevins nourris, sur le Redon, un affluent du lac Léman. On trouve sur le Redon une situation typique de nombreux affluents du Léman : une zone aval ouverte sur le lac mais rapidement interrompue par un obstacle empêchant la remontée des truites de lac. Des relâchers d’alevins nourris issus d’œufs de géniteurs sauvages de truite de lac ou de géniteurs domestiques, pratiqués en fin de printemps-début été à des densités de 40-60 ind./100 m2, fournissent un recrutement additionnel important pouvant constituer la part dominante du peuplement automnal en 0 +, puis 1 +. Sur les zones ouvertes à la pêche, colonisées ou non par la truite de lac, la densité de la population automnale en place s’effondre entre le stade 1 + et les stades > 1 +. Les résultats comparatifs entre zones ouvertes ou fermées à la pêche indiquent que la pêche peut être un facteur de mortalité important. La dynamique comparée des truites d’origine lacustre ou sédentaire suggère l’existence d’un taux de sédentarisation plus faible pour les 1 + issus de truites de lac comparativement aux 1 + issus de la fraie de truites sédentaires en zone de réserve. Une expérimentation suggère l’existence de mouvements de dévalaison ayant lieu avant octobre et touchant préférentiellement les 0 + d’origine lacustre ayant eu la croissance initiale la plus forte. L’étude montre que : - des alevins nourris d’origine lacustre ou domestique, relâchés en fin de printemps-début été, fournissent des géniteurs de truite de lac remontant dans la rivière de relâcher, avec cependant une proportion moindre (4 fois dans le cas de l’origine domestique comparativement à l’origine lacustre. Malgré leur forte contribution aux stades de juvéniles 0 + et 1 +, les alevins domestiques de pisciculture contribuent peu aux retours de g

A utility perspective on radiation worker access control systems

International Nuclear Information System (INIS)

Watson, B.A.; Goff, T.E.

1984-01-01

Based on an evaluation of the current commercial Radiation Worker Access Control Software Systems, Baltimore Gas and Electric Company has elected to design and develop a site specific access control and accountability system for the Calvert Cliffs Nuclear Power Plant. The vendor provided systems allow for radiation worker access control based on training and external exposure records and authorizations. These systems do not afford internal exposure control until after bioassay measurements or maximum permissible concentration-hours are tabulated. The vendor provided systems allow for data trending for ALARA purposes, but each software package must be modified to meet site specific requirements. Unlike the commercial systems, the Calvert Cliffs Radiological Controls and Accountability System (RCAS) will provide radiation worker exposure control, both internal and external. The RCAS is designed to fulfill the requirements by integrating the existing Radiation Safety, Dosemetry, and Training data bases with a comprehensive radiological surveillance program. Prior to each worker's entry into the Radiological Control Area; his training and qualifications, radiation exposure history and authorization, will be compared with administrative controls, such as radiation work permits, and respiratory protection requirements and the radiological conditions in the work area. The RCAS, a computer based applied health physics access control system is described as it is presently configured for development. The mechanisms for enhancing worker internal and external exposure controls are discussed. Proposed data application to both the Calvert Cliffs ALARA and outage planning programs is included

The ARAC client system: network-based access to ARAC

International Nuclear Information System (INIS)

Leach, M J; Sumikawa, D; Webster, C

1999-01-01

The ARAC Client System allows users (such as emergency managers and first responders) with commonly available desktop and laptop computers to utilize the central ARAC system over the Internet or any other communications link using Internet protocols. Providing cost-effective fast access to the central ARAC system greatly expands the availability of the ARAC capability. The ARAC Client system consists of (1) local client applications running on the remote user's computer, and (2) ''site servers'' that provide secure access to selected central ARAC system capabilities and run on a scalable number of dedicated workstations residing at the central facility. The remote client applications allow users to describe a real or potential them-bio event, electronically sends this information to the central ARAC system which performs model calculations, and quickly receive and visualize the resulting graphical products. The site servers will support simultaneous access to ARAC capabilities by multiple users. The ARAC Client system is based on object-oriented client/server and distributed computing technologies using CORBA and Java, and consists of a large number of interacting components

The UV spectrum of the BL Lac object PKS 0521-36

International Nuclear Information System (INIS)

Danziger, I.J.; Bergeron, J.; Maraschi, L.; Treves, A.; Milan Univ.; Tanzi, E.G.

1983-01-01

Ultraviolet observations (1200 to 3000 A) with the IUE satellite of the BL Lac object PKS 0521-36 are presented. The only emission line which appears clearly in the spectrum is Lyα, which is asymmetric with a component displaced approx. 3000 km s - 1 to the red. The intensity of the line and the upper limits on other lines are compared with the model calculations on QSOs and Seyfert nuclei by Kwan and Krolik. The continuous energy distribution is discussed, combining non-simultaneous observations from the ultraviolet to the infrared. The spectral range of the non-thermal source from far IR to far UV can be described by a single power law of index -1.5. (author)

Various mutations compensate for a deleterious lacZα insert in the replication enhancer of M13 bacteriophage.

Directory of Open Access Journals (Sweden)

Emily M Zygiel

Full Text Available M13 and other members of the Ff class of filamentous bacteriophages have been extensively employed in myriad applications. The Ph.D. series of phage-displayed peptide libraries were constructed from the M13-based vector M13KE. As a direct descendent of M13mp19, M13KE contains the lacZα insert in the intergenic region between genes IV and II, where it interrupts the replication enhancer of the (+ strand origin. Phage carrying this 816-nucleotide insert are viable, but propagate in E. coli at a reduced rate compared to wild-type M13 phage, presumably due to a replication defect caused by the insert. We have previously reported thirteen compensatory mutations in the 5'-untranslated region of gene II, which encodes the replication initiator protein gIIp. Here we report several additional mutations in M13KE that restore a wild-type propagation rate. Several clones from constrained-loop variable peptide libraries were found to have ejected the majority of lacZα gene in order to reconstruct the replication enhancer, albeit with a small scar. In addition, new point mutations in the gene II 5'-untranslated region or the gene IV coding sequence have been spontaneously observed or synthetically engineered. Through phage propagation assays, we demonstrate that all these genetic modifications compensate for the replication defect in M13KE and restore the wild-type propagation rate. We discuss the mechanisms by which the insertion and ejection of the lacZα gene, as well as the mutations in the regulatory region of gene II, influence the efficiency of replication initiation at the (+ strand origin. We also examine the presence and relevance of fast-propagating mutants in phage-displayed peptide libraries.

Bird communities of contrasting semi-natural habitats of Lac bay, Bonaire, during the fall migration season, 2011

NARCIS (Netherlands)

Debrot, A.O.; Bemmelen, van R.S.A.; Ligon, J.

2013-01-01

The mangrove and seagrass lagoon of Lac Bay on Bonaire covers an area of roughly 700 ha. It is home to endangered green sea turtles, Chelonia mydas, and the Caribbean queen conch, Strombus gigas, and is a roosting and breeding area for several birds. Based on its nature values this 7 km2 bay has

An Analysis of Light Periods of BL Lac Object S5 0716+714 with the MUSIC Algorithm

Science.gov (United States)

Tang, Jie

2012-07-01

The multiple signal classification (MUSIC) algorithm is introduced to the estimation of light periods of BL Lac objects. The principle of the MUSIC algorithm is given, together with a testing on its spectral resolution by using a simulative signal. From a lot of literature, we have collected a large number of effective observational data of the BL Lac object S5 0716+714 in the three optical wavebands V, R, and I from 1994 to 2008. The light periods of S5 0716+714 are obtained by means of the MUSIC algorithm and average periodogram algorithm, respectively. It is found that there exist two major periodic components, one is the period of (3.33±0.08) yr, another is the period of (1.24±0.01) yr. The comparison of the performances of periodicity analysis of two algorithms indicates that the MUSIC algorithm has a smaller requirement on the sample length, as well as a good spectral resolution and anti-noise ability, to improve the accuracy of periodicity analysis in the case of short sample length.

Transcription of two adjacent carbohydrate utilization gene clusters in Bifidobacterium breve UCC2003 is controlled by LacI- and repressor open reading frame kinase (ROK)-type regulators.

Science.gov (United States)

O'Connell, Kerry Joan; Motherway, Mary O'Connell; Liedtke, Andrea; Fitzgerald, Gerald F; Paul Ross, R; Stanton, Catherine; Zomer, Aldert; van Sinderen, Douwe

2014-06-01

Members of the genus Bifidobacterium are commonly found in the gastrointestinal tracts of mammals, including humans, where their growth is presumed to be dependent on various diet- and/or host-derived carbohydrates. To understand transcriptional control of bifidobacterial carbohydrate metabolism, we investigated two genetic carbohydrate utilization clusters dedicated to the metabolism of raffinose-type sugars and melezitose. Transcriptomic and gene inactivation approaches revealed that the raffinose utilization system is positively regulated by an activator protein, designated RafR. The gene cluster associated with melezitose metabolism was shown to be subject to direct negative control by a LacI-type transcriptional regulator, designated MelR1, in addition to apparent indirect negative control by means of a second LacI-type regulator, MelR2. In silico analysis, DNA-protein interaction, and primer extension studies revealed the MelR1 and MelR2 operator sequences, each of which is positioned just upstream of or overlapping the correspondingly regulated promoter sequences. Similar analyses identified the RafR binding operator sequence located upstream of the rafB promoter. This study indicates that transcriptional control of gene clusters involved in carbohydrate metabolism in bifidobacteria is subject to conserved regulatory systems, representing either positive or negative control.

Channel Access Algorithm Design for Automatic Identification System

Institute of Scientific and Technical Information of China (English)

Oh Sang-heon; Kim Seung-pum; Hwang Dong-hwan; Park Chan-sik; Lee Sang-jeong

2003-01-01

The Automatic Identification System (AIS) is a maritime equipment to allow an efficient exchange of the navigational data between ships and between ships and shore stations. It utilizes a channel access algorithm which can quickly resolve conflicts without any intervention from control stations. In this paper, a design of channel access algorithm for the AIS is presented. The input/output relationship of each access algorithm module is defined by drawing the state transition diagram, dataflow diagram and flowchart based on the technical standard, ITU-R M.1371. In order to verify the designed channel access algorithm, the simulator was developed using the C/C++ programming language. The results show that the proposed channel access algorithm can properly allocate transmission slots and meet the operational performance requirements specified by the technical standard.

Radio emission from quasars and BL Lac objects by coherent plasma oscillation and stimulated Compton scattering

International Nuclear Information System (INIS)

Colgate, S.A.; Petschek, A.G.

1978-01-01

The full radiation spectrum of quasars and BL Lac objects is interpreted as due to a dependent combination of a soft plasma oscillation source at 2ν/sub P/ and bremsstrahlung. Previous work of the plasma oscillation radiation is extended into the radio part of the spectrum and it is shown how the high brightness temperature observations of BL Lac objects [kT/sub b/ (100 MHz) approximate = 3 x 10 5 mc 2 ] are a reasonable consequence of a lower external plasma density and ejection as required for the observed lack of emission lines. Two extreme cases are considered, the one where the plasma oscillations are suddenly extinguished and only stimulated Compton scattering remains and a second case of a constant source of plasma oscillations but a graded surface density. The first case gives 1/100 of the required brightness temperature and the second gives 100 times too large a brightness temperature and also a x 10 too large a radius. It is believed reasonable to invoke a combination of both processes to explain the observed radio spectrum. This model circumvents the self-Compton x-ray flux difficulty of incoherent synchrotron emission

Hydrogen production by Escherichia coli {delta}hycA {delta}lacI using cheese whey as substrate

Energy Technology Data Exchange (ETDEWEB)

Rosales-Colunga, Luis Manuel; Ordonez, Leandro G.; De Leon-Rodriguez, Antonio (Division de Biologia Molecular, Instituto Potosino de Investigacion Cientifica y Tecnologica, Camino a la Presa San Jose 2055, Col. Lomas 4a secc. CP 78216, San Luis Potosi, SLP. Mexico); Razo-Flores, Elias; Alatriste-Mondragon, Felipe (Division de Ciencias Ambientales, Instituto Potosino de Investigacion Cientifica y Tecnologica, Camino a la Presa San Jose 2055, Col. Lomas 4a secc. CP 78216, San Luis Potosi, SLP. Mexico)

2010-01-15

This study reports a fermentative hydrogen production by Escherichia coli using cheese whey as substrate. To improve the biohydrogen production, an E. coli {delta}hycA {delta}lacI strain (WDHL) was constructed. The absence of hycA and lacI genes had a positive effect on the biohydrogen production. The strain produced 22% more biohydrogen in a shorter time than the wild-type (WT) strain. A Box-Behnken experimental design was used to optimize pH, temperature and substrate concentration. The optimal initial conditions for biohydrogen production by WDHL strain were pH 7.5, 37 C and 20 g/L of cheese whey. The specific production rate was improved from 3.29 mL H{sub 2}/optical density at 600 nm (OD{sub 600nm}) unit-h produced by WDHL under non-optimal conditions to 5.88 mL H{sub 2}/OD{sub 600nm} unit-h under optimal conditions. Using optimal initial conditions, galactose can be metabolized by WDHL strain. The maximum yield obtained was 2.74 mol H{sub 2}/mol lactose consumed, which is comparable with the yield reached in other hydrogen production processes with Clostridium sp. or mixed cultures. (author)

Déclin et restauration de la population de truites lacustres (Salmo trutta lacustris L. du lac de Constance

Directory of Open Access Journals (Sweden)

RUHLÉ C.

1990-10-01

Full Text Available Le déclin de la population de truites migratrices du lac de Constance a débuté vers 1950 quand un barrage a été construit sur le Rhin, affluent principal de ce lac, coupant ainsi l'accès aux plus importantes frayères. Ceci a suffi de prétexte pour renoncer à une longueur de capture garantissant la reproduction naturelle. Par la suite, la population en train de diminuer a servi de justification pour des déversements importants de truites arc-en-ciel. Un désintérêt croissant pour le maintien de frayères dans les affluents secondaires a, finalement, contribué à la baisse des captures de 12.000 kg à 3.000 kg entre 1950 et 1980.Les mesures réalisées au cours des dernières années pour restaurer la population de truites lacustres ont du succès. Il s'agit surtout de : — la détermination d'une nouvelle longueur de capture ainsi que de périodes de protection respectant la reproduction des truites migrant à longue et à courte distance,— l'élevage de stocks de géniteurs, — les déversements forcés et effectués surtout en affluents (au lieu du lac,— l'interdiction d'immersions de truites arc-en-ciel,— l'abolition de barrages. Le succès se manifeste par un nombre croissant de truites observées frayant dans les affluents ainsi que par des captures de plus en plus nombreuses faites par la pêche professionnelle.

Development of an access control system for the LHD experimental hall

International Nuclear Information System (INIS)

Kawano, T.; Inoue, N.; Sakuma, Y.; Uda, T.; Yamanishi, H.; Miyake, H.; Tanahashi, S.; Motozima, O.

2000-01-01

An access control system for the LHD (Large Helical Device) experimental hall had been constructed and its practical operation started in March 1998. Continuously, the system has been improved. The present system keeps watch on involved entrance and exit for the use of persons at four entrances by using five turnstile gates while watching on eight shielding doors at eight positions (four entrances, three carriage entrances and a hall overview) and a stairway connecting the LHD main hall with the LHD basement. Besides, for the security of safety operation of the LHD, fifteen kinds of interlock signals are exchanged between the access control system and the LHD control system. Seven of the interlock signals are properly sent as the occasional demands from the access control system to the LHD control system, in which three staple signals are B Personnel Access to Controlled Area, D Shielding Door Closed, and E No Entrance. It is important that any plasma experiments of the LHD are not permitted while the signal B being sent or D being not sent. The signal E is sent to inform the LHD control system that the turnstile gates are locked. All the plasma experiments should not be done unless the lock procedure of the turnstile is confirmed. When the turnstile gates are locked, any persons cannot enter into the LHD controlled area, but are permissible to exit only. Six of the interlock signals are used to send the information of the working at that time in the LHD controlled area to the access control system. When one signal of the operation mode is sent to the access control system from the LHD, the access control system sets the turnstile gate in situation corresponding to the operation mode, A Equipment Operation, B Vacuum Pumping, C Coil Cooling, D Coil Excitation, and E Plasma Experiment. If the access control system receives, for example, the signal B, this system sets the turnstile gate in the condition of control such that only persons assigned to the work of vacuum

Database design for Physical Access Control System for nuclear facilities

Energy Technology Data Exchange (ETDEWEB)

Sathishkumar, T., E-mail: satishkumart@igcar.gov.in; Rao, G. Prabhakara, E-mail: prg@igcar.gov.in; Arumugam, P., E-mail: aarmu@igcar.gov.in

2016-08-15

Highlights: • Database design needs to be optimized and highly efficient for real time operation. • It requires a many-to-many mapping between Employee table and Doors table. • This mapping typically contain thousands of records and redundant data. • Proposed novel database design reduces the redundancy and provides abstraction. • This design is incorporated with the access control system developed in-house. - Abstract: A (Radio Frequency IDentification) RFID cum Biometric based two level Access Control System (ACS) was designed and developed for providing access to vital areas of nuclear facilities. The system has got both hardware [Access controller] and software components [server application, the database and the web client software]. The database design proposed, enables grouping of the employees based on the hierarchy of the organization and the grouping of the doors based on Access Zones (AZ). This design also illustrates the mapping between the Employee Groups (EG) and AZ. By following this approach in database design, a higher level view can be presented to the system administrator abstracting the inner details of the individual entities and doors. This paper describes the novel approach carried out in designing the database of the ACS.

Database design for Physical Access Control System for nuclear facilities

International Nuclear Information System (INIS)

Sathishkumar, T.; Rao, G. Prabhakara; Arumugam, P.

2016-01-01

Highlights: • Database design needs to be optimized and highly efficient for real time operation. • It requires a many-to-many mapping between Employee table and Doors table. • This mapping typically contain thousands of records and redundant data. • Proposed novel database design reduces the redundancy and provides abstraction. • This design is incorporated with the access control system developed in-house. - Abstract: A (Radio Frequency IDentification) RFID cum Biometric based two level Access Control System (ACS) was designed and developed for providing access to vital areas of nuclear facilities. The system has got both hardware [Access controller] and software components [server application, the database and the web client software]. The database design proposed, enables grouping of the employees based on the hierarchy of the organization and the grouping of the doors based on Access Zones (AZ). This design also illustrates the mapping between the Employee Groups (EG) and AZ. By following this approach in database design, a higher level view can be presented to the system administrator abstracting the inner details of the individual entities and doors. This paper describes the novel approach carried out in designing the database of the ACS.

40 CFR 264.34 - Access to communications or alarm system.

Science.gov (United States)

2010-07-01

... FACILITIES Preparedness and Prevention § 264.34 Access to communications or alarm system. (a) Whenever... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Access to communications or alarm system. 264.34 Section 264.34 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID...

78 FR 3911 - Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN; Final Comprehensive...

Science.gov (United States)

2013-01-17

... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R3-R-2012-N259; FXRS1265030000-134-FF03R06000] Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN; Final Comprehensive... significant impact (FONSI) for the environmental assessment (EA) for Big Stone National Wildlife Refuge...

Need an Information Security in Access Control System?

Directory of Open Access Journals (Sweden)

V. R. Petrov

2011-12-01

Full Text Available The purpose of this paper is the general problems of information security in access control system. The field of using is the in project of reconstruction Physical protection system.

Deposition mechanism and microstructure of laser-assisted cold-sprayed (LACS) Al-12 wt.%Si coatings: effects of laser power

CSIR Research Space (South Africa)

Olakanmi, EO

2013-06-01

Full Text Available at the substrate and build up a coating. To circumvent the processing problems associated with cold-spray (CS) deposition of low-temperature, corrosion-resistant Al-12 wt.%Si coatings, a preliminary investigation detailing the effect of laser power on its LACS...

RFID Based Security Access Control System with GSM Technology

OpenAIRE

Peter Adole; Joseph M. Môm; Gabriel A. Igwue

2016-01-01

The security challenges being encountered in many places today require electronic means of controlling access to secured premises in addition to the available security personnel. Various technologies were used in different forms to solve these challenges. The Radio Frequency Identification (RFID) Based Access Control Security system with GSM technology presented in this work helps to prevent unauthorized access to controlled environments (secured premises). This is achieved mainly...

The diluvial rains of Saguenay-Lac-Saint-Jean : status one year after

International Nuclear Information System (INIS)

Henri, N.; Beauchemin, G.; Alonso, M.; Gelinas, M.

1997-01-01

The status of damages and reconstruction in the Saguenay-Lac-Saint-Jean region, one year after the catastrophic torrential rain storm of July 1996 was presented. Numerous detailed maps and photographs of the principal washed-out, destroyed and damaged regions were presented, along with maps and photographs of the same areas after reconstruction, repair and landscaping. The maps show the different river beds, urban, and rural districts that were subjected to the catastrophic washouts, landslides and soil collapses. The report also includes a summary of the repair costs by municipal regions and the financial aid received by the region to help in the reconstruction effort. tabs., figs

A Fine-Grained Data Access Control System in Wireless Sensor Network

Directory of Open Access Journals (Sweden)

Boniface K. Alese

2015-12-01

Full Text Available The evolving realities of Wireless Sensor Network (WSN deployed to various terrain of life require serving multiple applications. As large amount of sensed data are distributed and stored in individual sensors nodes, the illegal access to these sensitive data can be devastating. Consequently, data insecurity becomes a big concern. This study, therefore, proposes a fine-grained access control system which only requires the right set of users to access a particular data, based on their access privileges in the sensor networks. It is designed using Priccess Protocol with Access policy formulation adopting the principle of Bell Lapadula model as well as Attribute-Based Encryption (ABE to control access to sensor data. The functionality of the proposed system is simulated using Netbeans. The performance analysis of the proposed system using execution time and size of the key show that the higher the key size, the harder it becomes for the attacker to hack the system. Additionally, the time taken for the proposed work is lesser which makes the work faster than the existing work. Consequently, a well secure interactive web-based application that could facilitates the field officers access to stored data in safe and secure manner is developed.

CDC STATE System Tobacco Legislation - Youth Access

Data.gov (United States)

U.S. Department of Health & Human Services — 1995-2018. Centers for Disease Control and Prevention (CDC). State Tobacco Activities Tracking and Evaluation (STATE) System. Legislation—Youth Access. The STATE...

Towards ubiquitous access of computer-assisted surgery systems.

Science.gov (United States)

Liu, Hui; Lufei, Hanping; Shi, Weishong; Chaudhary, Vipin

2006-01-01

Traditional stand-alone computer-assisted surgery (CAS) systems impede the ubiquitous and simultaneous access by multiple users. With advances in computing and networking technologies, ubiquitous access to CAS systems becomes possible and promising. Based on our preliminary work, CASMIL, a stand-alone CAS server developed at Wayne State University, we propose a novel mobile CAS system, UbiCAS, which allows surgeons to retrieve, review and interpret multimodal medical images, and to perform some critical neurosurgical procedures on heterogeneous devices from anywhere at anytime. Furthermore, various optimization techniques, including caching, prefetching, pseudo-streaming-model, and compression, are used to guarantee the QoS of the UbiCAS system. UbiCAS enables doctors at remote locations to actively participate remote surgeries, share patient information in real time before, during, and after the surgery.

Free-space optical code-division multiple-access system design

Science.gov (United States)

Jeromin, Lori L.; Kaufmann, John E.; Bucher, Edward A.

1993-08-01

This paper describes an optical direct-detection multiple access communications system for free-space satellite networks utilizing code-division multiple-access (CDMA) and forward error correction (FEC) coding. System performance is characterized by how many simultaneous users operating at data rate R can be accommodated in a signaling bandwidth W. The performance of two CDMA schemes, optical orthogonal codes (OOC) with FEC and orthogonal convolutional codes (OCC), is calculated and compared to information-theoretic capacity bounds. The calculations include the effects of background and detector noise as well as nonzero transmitter extinction ratio and power imbalance among users. A system design for 10 kbps multiple-access communications between low-earth orbit satellites is given. With near- term receiver technology and representative system losses, a 15 W peak-power transmitter provides 10-6 BER performance with seven interfering users and full moon background in the receiver FOV. The receiver employs an array of discrete wide-area avalanche photodiodes (APD) for wide field of view coverage. Issues of user acquisition and synchronization, implementation technology, and system scalability are also discussed.

ACCESS TO A COMPUTER SYSTEM. BETWEEN LEGAL PROVISIONS AND TECHNICAL REALITY

Directory of Open Access Journals (Sweden)

Maxim DOBRINOIU

2016-05-01

Full Text Available Nowadays, on a rise of cybersecurity incidents and a very complex IT&C environment, the national legal systems must adapt in order to properly address the new and modern forms of criminality in cyberspace. The illegal access to a computer system remains one of the most important cyber-related crimes due to its popularity but also from the perspective as being a door opened to computer data and sometimes a vehicle for other tech crimes. In the same time, the information society services slightly changed the IT paradigm and represent the new interface between users and systems. Is true that services rely on computer systems, but accessing services goes now beyond the simple accessing computer systems as commonly understood by most of the legislations. The article intends to explain other sides of the access related to computer systems and services, with the purpose to advance possible legal solutions to certain case scenarios.

Polarization burst in the BL Lac object AO 0235 + 164

Energy Technology Data Exchange (ETDEWEB)

Impey, C D; Brand, P W.J.L. [Edinburgh Univ. (UK). Dept. of Astronomy; Tapia, S [Steward Observatory, Tucson, AZ (USA)

1982-01-01

Simultaneous infrared and optical polarimetry and photometry have been obtained for AO 0235 + 164 covering a five night period. The object underwent a polarization burst during which the 2.2 ..mu..m polarization rose from 17.5 to 28.7 per cent and fell again to 14.9 per cent. At its peak the degree of optical polarization was 43.9 per cent, the highest linear polarization observed in a BL Lac object. The data show the degree of polarization to increase towards shorter wavelengths, and the effect is inconsistent with either dilution by a galactic component or simple one-component synchrotron models. The large changes in polarization are not accompanied by large changes in flux, a result which is difficult to explain using conventional models of these objects. Other implications of the luminosity, polarization and variability are discussed.

The entire network topology display system of terminal communication access network

OpenAIRE

An Yi

2016-01-01

Now order terminal communication access network is network technology in Shanxi Province is diversiform, device type complex, lack of unified technical standard, the terminal communication access network management system of construction constitutes a great obstacle. Need to build a “unified communication interface and communication standard, unified communications network management” of the terminal communication access network cut in the integrated network management system, for the termina...

The COROT ground-based archive and access system

Science.gov (United States)

Solano, E.; González-Riestra, R.; Catala, C.; Baglin, A.

2002-01-01

A prototype of the COROT ground-based archive and access system is presented here. The system has been developed at LAEFF and it is based on the experience gained at Laboratorio de Astrofisica Espacial y Fisica Fundamental (LAEFF) with the INES (IUE Newly Extracted System) Archive.

DNA adducts, mutant frequencies and mutation spectra in λlacZ transgenic mice treated with N-nitrosodimethylamine

NARCIS (Netherlands)

Souliotis, V.L.; Delft, J.H.M. van; Steenwinkel, M.-J.S.T.; Baan, R.A.; Kyrtopoulos, S.A.

1998-01-01

Groups of λlacZ transgenic mice were treated i.p. with N-nitrosodimethylamine (NDMA) as single doses of 5 mg/kg or 10 mg/kg or as 10 daily doses of 1 mg/kg and changes in DNA N7- or O6-methylguanine or the repair enzyme O6-alkylguanine-DNA alkyltransferase (AGT) were followed for up to 14 days in

L'habitat à une échelle globale : importance respective de l'immigration et de l'extinction pour les peuplements de poissons des petits lacs

Directory of Open Access Journals (Sweden)

TONN W. M.

1995-04-01

Full Text Available Les deux processus qui déterminent la structure des communautés dans les habitats insulaires sont l'immigration d'espèces vers une communauté et l'extinction de celles qui étaient présentes auparavant. Bien que l'immigration et l'extinction se produisent généralement à des échelles supérieures à celles qu'il est possible d'étudier avec des expériences plannifiées, les écologistes peuvent améliorer leur compréhension de ces processus par l'analyse des distributions observées ; l'isolation, le caractère discret et la réplication des systèmes insulaires présentent des avantages pour réaliser de telles analyses. Comme pour les communautés observées sur de vraies îles, la structure des peuplements de poissons dans les petits lacs forestiers est le résultat de l'immigration et de l'extinction. L'importance relative de ces processus peut dépendre des caractéristiques d'habitat des lacs et des espèces présentes, ainsi que du cadre régional et historique des lacs étudiés. Dans une région donnée, la composition des peuplements locaux de poissons peut être reliée à un ensemble particulier de conditions d'habitat et, dans la mesure où ces facteurs peuvent être liés à l'immigration et à l'extinction, il devrait être possible d'analyser les relations peuplement-environnement pour en déduire l'importance relative de ces processus dans la formation de peuplements locaux dans et entre les régions et les continents. Nous avons réalisé des analyses à large échelle des relations peuplement-environnement des petits lacs forestiers de quatre régions tempérées d'Europe et d'Amérique du Nord ; l'utilisation d'une série d'analyses canonique partielle des correspondances nous a permis de distinguer la variation due aux relations peuplements-environnement d'un ensemble de facteurs associés à l'immigration contre l'extinction. Les isolations passées et présentes varient selon les lacs et les régions, comme la

ASCA and Contemporaneous Ground-based Observations of the BL Lacertae Objects 1749+096 and 2200+420 (BL Lac)

International Nuclear Information System (INIS)

Sambruna, R.M.; Ghisellini, G.; Hooper, E.; Kollgaard, R.I.; Pesce, J.E.; Urry, C.M.

1999-01-01

We present ASCA observations of the radio-selected BL Lacertae objects 1749+096 (z=0.32) and 2200+420 (BL Lac, z=0.069) performed in 1995 September and November, respectively. The ASCA spectra of both sources can be described as a first approximation by a power law with photon index Γ∼2. This is flatter than for most X-ray endash selected BL Lacs observed with ASCA, in agreement with the predictions of current blazar unification models. While 1749+096 exhibits tentative evidence for spectral flattening at low energies, a concave continuum is detected for 2200+420: the steep low-energy component is consistent with the high-energy tail of the synchrotron emission responsible for the longer wavelengths, while the harder tail at higher energies is the onset of the Compton component. The two BL Lacs were observed with ground-based telescopes from radio to TeV energies contemporaneously with ASCA. The spectral energy distributions are consistent with synchrotron self-Compton emission from a single homogeneous region shortward of the IR/optical wavelengths, with a second component in the radio domain related to a more extended emission region. For 2200+420, comparing the 1995 November state with the optical/GeV flare of 1997 July, we find that models requiring inverse Compton scattering of external photons provide a viable mechanism for the production of the highest (GeV) energies during the flare. In particular, an increase of the external radiation density and of the power injected in the jet can reproduce the flat γ-ray continuum observed in 1997 July. A directly testable prediction of this model is that the line luminosity in 2200+420 should vary shortly after (∼1 month) a nonthermal synchrotron flare. copyright copyright 1999. The American Astronomical Society

CDC STATE System Tobacco Legislation - Youth Access

Data.gov (United States)

U.S. Department of Health & Human Services — 1995-2016. Centers for Disease Control and Prevention (CDC). State Tobacco Activities Tracking and Evaluation (STATE) System. Legislation—Youth Access. The STATE...

MAST's Integrated Data Access Management system: IDAM

International Nuclear Information System (INIS)

Muir, D.G.; Appel, L.; Conway, N.J.; Kirk, A.; Martin, R.; Meyer, H.; Storrs, J.; Taylor, D.; Thomas-Davies, N.; Waterhouse, J.

2008-01-01

A new Integrated Data Access Management system, IDAM, has been created to address specific data management issues of the MAST spherical Tokamak. For example, this system enables access to numerous file formats, both legacy and modern (IDA, Ufile, netCDF, HDF5, MDSPlus, PPF, JPF). It adds data quality values at the signal level, and automatically corrects for problems in data: in timings, calibrations, and labelling. It also builds new signals from signal components. The IDAM data server uses a hybrid XML-relational database to record how data are accessed, whether locally or remotely, and how alias and generic signal names are mapped to true names. Also, XML documents are used to encode the details of data corrections, as well as definitions of composite signals and error models. The simple, user friendly, API and accessor function library, written in C on Linux, is available for applications in C, C++, IDL and Fortran-90/95/2003 with good performance: a MAST plasma current trace (28 kbytes of data), requested using a generic name and with data corrections applied, is delivered over a 100 Mbit/s network in ∼13 ms

Water in the Cratonic Mantle: Insights from FTIR Data on Lac De Gras Xenoliths (Slave Craton, Canada)

Science.gov (United States)

Peslier, Anne H.; Brandon, Alan D.; Schaffer, Lillian Aurora; O'Reilly, Suzanne Yvette; Griffin, William L.; Morris, Richard V.; Graff, Trevor G.; Agresti, David G.

2014-01-01

The mantle lithosphere beneath the cratonic part of continents is the deepest (> 200 km) and oldest (>2-3 Ga) on Earth, remaining a conundrum as to how these cratonic roots could have resisted delamination by asthenospheric convection over time. Water, or trace H incorporated in mineral defects, could be a key player in the evolution of continental lithosphere because it influences melting and rheology of the mantle. Mantle xenoliths from the Lac de Gras kimberlite in the Slave craton were analyzed by FTIR. The cratonic mantle beneath Lac de Gras is stratified with shallow (water contents extending to higher values than those from the shallow ones. The FTIR spectra of olivines from the shallow samples have more prominent Group II OH bands compared to the olivines from the deep samples, consistent with a more oxidized mantle environment. The range of olivine water content is similar to that observed in Kaapvaal craton peridotites at the same depths (129-184 km) but does not extend to as high values as those from Udachnaya (Siberian craton). The Slave, Kaapvaal and Siberian cratons will be compared in terms of water content distribution, controls and role in cratonic root longevity.

p21-LacZ reporter mice reflect p53-dependent toxic insult

International Nuclear Information System (INIS)

Vasey, Douglas B.; Wolf, C. Roland; MacArtney, Thomas; Brown, Ken; Whitelaw, C. Bruce A.

2008-01-01

There is an urgent need to discover less toxic and more selective drugs to treat disease. The use of transgenic mice that report on toxic insult-induced transcription can provide a valuable tool in this regard. To exemplify this strategy, we have generated transgenic mice carrying a p21-LacZ transgene. Transgene activity reflected endogenous p21 gene activation in various tissues, displayed compound-specific spatial expression signatures in the brain and immune tissues and enabled p53-dependent and p53-independent responses to be identified. We discuss the application of these mice in delineating the molecular events in normal cellular growth and disease and for the evaluation of drug toxicity

Distributed Access View Integrated Database (DAVID) system

Science.gov (United States)

Jacobs, Barry E.

1991-01-01

The Distributed Access View Integrated Database (DAVID) System, which was adopted by the Astrophysics Division for their Astrophysics Data System, is a solution to the system heterogeneity problem. The heterogeneous components of the Astrophysics problem is outlined. The Library and Library Consortium levels of the DAVID approach are described. The 'books' and 'kits' level is discussed. The Universal Object Typer Management System level is described. The relation of the DAVID project with the Small Business Innovative Research (SBIR) program is explained.

Optimizing data access in the LAMPF control system

International Nuclear Information System (INIS)

Schaller, S.C.; Corley, J.K.; Rose, P.A.

1985-01-01

The LAMPF control system data access software offers considerable power and flexibility to application programs through symbolic device naming and an emphasis on hardware independence. This paper discusses optimizations aimed at improving the performance of the data access software while retaining these capabilities. The only aspects of the optimizations visible to the application programs are ''vector devices'' and ''aggregate devices.'' A vector device accesses a set of hardware related data items through a single device name. Aggregate devices allow run-time optimization of references to groups of unrelated devices. Optimizations not visible on the application level include careful handling of: network message traffic; the sharing of global resources; and storage allocation

The ultraviolet to X-ray continua of BL Lac objects

International Nuclear Information System (INIS)

George, I.M.; Warwick, R.S.; McHardy, I.M.

1988-01-01

The results from EXOSAT observations of three X-ray bright BL Lacertae objects, Mrk 501, 1218 + 304 and Mrk 180 are presented. All three sources have soft power-law X-ray spectra with low-energy cut-offs consistent with absorption in the line-of-sight gas column density through our own galaxy. The three objects also exhibit significant spectral variability in the X-ray band on time-scales ranging from a few days to a year. In each case, X-ray flux and spectral index appear to be correlated, in the sense that the X-ray spectrum hardens as the source brightens. The intrinsic ultraviolet to X-ray spectrum of these and several other X-ray bright BL Lac objects can be modelled as a power-law continuum of energy index ∼1.0 below about 0.1 keV, above which the spectral slope steepens. (author)

Access control system for two person rule at Rokkasho Reprocessing Plant

International Nuclear Information System (INIS)

Yanagisawa, Sawako; Ino, Munekazu; Yamada, Noriyuki; Oota, Hiroto; Iwasaki, Mitsuaki; Kodani, Yoshiki; Iwamoto, Tomonori

2014-01-01

Following the amendment and enforcement of Regulation of Reprocessing Activity on March 29th 2012, two person rule has become compulsory for the specific rooms to counter and prevent the sabotage or theft of nuclear materials by the insiders at reprocessing plant in Japan. The rooms will include those which contains cooling systems for decay heat removal from spent fuels and so on, scavenging systems to prevent the hydrogen accumulation, and those which contains nuclear material. To ensure the two person rule at Rokkasho Reprocessing Plant, JNFL has recently, after comprehensive study, introduced efficient and effective access control system for the rooms mentioned above. The system is composed of bio-attestation devices, surveillance cameras and electronic locks to establish access control system. This report outlines the access control system for two person rule and introduces the operation. (author)

Efficient medium access control protocol for geostationary satellite systems

Institute of Scientific and Technical Information of China (English)

王丽娜; 顾学迈

2004-01-01

This paper proposes an efficient medium access control (MAC) protocol based on multifrequency-time division multiple access (MF-TDMA) for geostationary satellite systems deploying multiple spot-beams and onboard processing,which uses a method of random reservation access with movable boundaries to dynamically request the transmission slots and can transmit different types of traffic. The simulation results have shown that our designed MAC protocol can achieve a high bandwidth utilization, while providing the required quality of service (QoS) for each class of service.

A novel IPTV program multiplex access system to EPON

Science.gov (United States)

Xu, Xian; Liu, Deming; He, Wei; Lu, Xi

2007-11-01

With the rapid development of high speed networks, such as Ethernet Passive Optical Network (EPON), traffic patterns in access networks have evolved from traditional text-oriented service to the mixed text-, voice- and video- based services, leading to so called "Triple Play". For supporting IPTV service in EPON access network infrastructure, in this article we propose a novel IPTV program multiplex access system to EPON, which enables multiple IPTV program source servers to seamlessly access to IPTV service access port of optical line terminal (OLT) in EPON. There are two multiplex schemes, namely static multiplex scheme and dynamic multiplex scheme, in implementing the program multiplexing. Static multiplex scheme is to multiplex all the IPTV programs and forward them to the OLT, regardless of the need of end-users. While dynamic multiplex scheme can dynamically multiplex and forward IPTV programs according to what the end-users actually demand and those watched by no end-user would not be multiplexed. By comparing these two schemes, a reduced traffic of EPON can be achieved by using dynamic multiplex scheme, especially when most end-users are watching the same few IPTV programs. Both schemes are implemented in our system, with their hardware and software designs described.

Evaluating accessibility to Bangkok Metro Systems using multi-dimensional criteria across user groups

Directory of Open Access Journals (Sweden)

Duangporn Prasertsubpakij

2012-07-01

Full Text Available Metro systems act as fast and efficient transport systems for many modern metropolises; however, enhancing higher usage of such systems often conflicts with providing suitable accessibility options. The traditional approach of metro accessibility studies seems to be an ineffective measure to gage sustainable access in which the equal rights of all users are taken into account. Bangkok Metropolitan Region (BMR transportation has increasingly relied on the role of two mass rapid transport systems publicly called “BTS Skytrain” and “MRT Subway”, due to limited availability of land and massive road congestion; however, access to such transit arguably treats some vulnerable groups, especially women, the elderly and disabled people unfairly. This study constructs a multi-dimensional assessment of accessibility considerations to scrutinize how user groups access metro services based on BMR empirical case. 600 individual passengers at various stations were asked to rate the questionnaire that simultaneously considers accessibility aspects of spatial, feeder connectivity, temporal, comfort/safety, psychosocial and other dimensions. It was interestingly found by user disaggregated accessibility model that the lower the accessibility perceptions—related uncomfortable and unsafe environment conditions, the greater the equitable access to services, as illustrated by MRT — Hua Lumphong and MRT — Petchaburi stations. The study suggests that, to balance the access priorities of groups on services, policy actions should emphasize acceptably safe access for individuals, cost efficient feeder services connecting the metro lines, socioeconomic influences and time allocation. Insightful discussions on integrated approach balancing different dimensions of accessibility and recommendations would contribute to accessibility-based knowledge and potential propensity to use the public transits towards transport sustainability.

Largemouth bass (Micropterus salmoides Lacépède): reproduction management and larval rearing in Italy

OpenAIRE

A. Dees; P. Melotti; R. Vicenzi; A. Roncarati

2010-01-01

Micropterus salmoides (Lacépède) was originally present into the waters of the eastern United States of America, northern Mexico and southern Canada. This species can be distinguished from the other black basses by the fact that its mouth extends to and beyond the edge of the eye and the first and the second dorsal fins are almost separated by a deep dip and there are no scales on the soft rayed of the second dorsal fin.

Quasi-simultaneous observations of the BL Lac object MK 501 in X-ray, UV, visible, IR and radio frequencies

Science.gov (United States)

Kondo, D. M.; Worrall, D. M.; Mushotzky, R. F.; Hackney, R. L.; Hackney, K. H.; Oke, J. B.; Yee, H.; Neugebauer, G.; Matthews, K.; Feldman, P. A.

1980-01-01

Quasi-simultaneous observations of the BL Lacertae (Lac) objects MK 501 were performed for the first time at X-ray, ultraviolet, visible, infrared, and radio frequencies. The observed spectral slope from the X-ray to UV regions is positive and continuous, but that from the mid UV to visible light region becomes gradually flat and possibly turns down toward lower frequencies; the optical radio emission can not be accounted for by a single power law. Several theoretical models were considered for the emission mechanism. A quantitative comparison was performed with the synchrotron-self-Compton model; the total spectrum is found consistent with this model. The spectrum from visible light to X-ray is consistent with synchrotron radiation or with inverse-Compton scattering by a hot thermal cloud of electrons. The continuity of the spectral slope from X-ray to UV implied by the current data suggests that the previous estimates of the total luminosity of this BL Lac object is underestimated by a factor of about three or four.

Lactose carrier protein of Escherichia coli. Structure and expression of plasmids carrying the Y gene of the lac operon.

Science.gov (United States)

Teather, R M; Bramhall, J; Riede, I; Wright, J K; Fürst, M; Aichele, G; Wilhelm, U; Overath, P

1980-01-01

The previously described hybrid plasmid pC7 which carries lacI+O+delta(Z)Y+A+ on a 12.3 X 10(6)-Mr DNA fragment [Teather et al. (1978) Mol. Gen. Genet. 159, 239-248] was partially digested with the restriction endonuclease EcoRI under conditions reducing the recognition sequence to d(A-A-T-T) and ligated to the vector pB322. lac Y-carrying inserts of various sized (Mr 1.5-4.7 X 10(6)) were obtained. Hybrid plasmid pTE18 (2300-base-pair insert) carries part of the I (repressor) gene, the promotor-operator region, part of the Z (beta-galactosidase) gene, the Y (lactose carrier) gene and part of the A (transacetylase) gene. Upon induction of pTE18-harbouring strains the Y-gene product is expressed at a nearly constant rate for several generations and accumulates to a level of 12-16% of the total cytoplasmic membrane protein. Integration into the membrane leads to active carrier as judged by binding and transport measurements.

Thermal cracking in Lac du Bonnet granite during slow heating to 205 degrees celsius

International Nuclear Information System (INIS)

Chernis, P.J.; Robertson, P.B.

1993-09-01

Acoustic emissions (AE) were recorded as drill core samples of Lac du Bonnet granite were slowly heated to between 66 and 205 degrees celsius to evaluate the effects of temperature on the properties of rock samples. Longitudinal and shear velocities of the samples were measured, and Young's moduli, shear moduli and Poisson's ratios were calculated. No significant AE activity was detected until temperatures reached approximately 73-80 degrees celsius. Above this 'threshold' temperature, calculated rock properties decreased, and at 205 degrees celsius calculated Young's modulus, shear modulus, and Poisson's ratio were reduced by 30, 26, and 29% respectively

Development of Patient Status-Based Dynamic Access System for Medical Information Systems

Directory of Open Access Journals (Sweden)

Chang Won Jeong

2015-06-01

Full Text Available Recently, the hospital information system environment using IT communication technology and utilization of medical information has been increasing. In the medical field, the medical information system only supports the transfer of patient information to medical staff through an electronic health record, without information about patient status. Hence, it needs a method of real-time monitoring for the patient. Also, in this environment, a secure method in approaching healthcare through various smart devices is required. Therefore, in this paper, in order to classify the status of the patients, we propose a dynamic approach of the medical information system in a hospital information environment using the dynamic access control method. Also, we applied the symmetric method of AES (Advanced Encryption Standard. This was the best encryption algorithm for sending and receiving biological information. We can define usefulness as the dynamic access application service based on the final result of the proposed system. The proposed system is expected to provide a new solution for a convenient medical information system.

Accessing files in an Internet: The Jade file system

Science.gov (United States)

Peterson, Larry L.; Rao, Herman C.

1991-01-01

Jade is a new distribution file system that provides a uniform way to name and access files in an internet environment. It makes two important contributions. First, Jade is a logical system that integrates a heterogeneous collection of existing file systems, where heterogeneous means that the underlying file systems support different file access protocols. Jade is designed under the restriction that the underlying file system may not be modified. Second, rather than providing a global name space, Jade permits each user to define a private name space. These private name spaces support two novel features: they allow multiple file systems to be mounted under one directory, and they allow one logical name space to mount other logical name spaces. A prototype of the Jade File System was implemented on Sun Workstations running Unix. It consists of interfaces to the Unix file system, the Sun Network File System, the Andrew File System, and FTP. This paper motivates Jade's design, highlights several aspects of its implementation, and illustrates applications that can take advantage of its features.

Accessing files in an internet - The Jade file system

Science.gov (United States)

Rao, Herman C.; Peterson, Larry L.

1993-01-01

Jade is a new distribution file system that provides a uniform way to name and access files in an internet environment. It makes two important contributions. First, Jade is a logical system that integrates a heterogeneous collection of existing file systems, where heterogeneous means that the underlying file systems support different file access protocols. Jade is designed under the restriction that the underlying file system may not be modified. Second, rather than providing a global name space, Jade permits each user to define a private name space. These private name spaces support two novel features: they allow multiple file systems to be mounted under one directory, and they allow one logical name space to mount other logical name spaces. A prototype of the Jade File System was implemented on Sun Workstations running Unix. It consists of interfaces to the Unix file system, the Sun Network File System, the Andrew File System, and FTP. This paper motivates Jade's design, highlights several aspects of its implementation, and illustrates applications that can take advantage of its features.

Optimizing man-machine performance of a personnel access restriction security system

International Nuclear Information System (INIS)

Banks, W.W.; Moore, J.W.

1988-01-01

This paper describes a human engineering design and analysis effort for a major security system upgrade at a DOE facility. This upgrade was accomplished by replacing an obsolete and poorly human engineered security screening both the with a new, user oriented, semiautomated, computer-based access control system. Human factors engineers assisted the designer staff in specifying a security access interface to physically and cognitively accommodate all employees which included handicapped individuals in wheel chairs, and several employees who were severely disabled, both visually and aurally. The new access system was intended to control entry into sensitive exclusion areas by requiring personnel to enter a security screening booth and interact with card reader devices and a-simple-to-operate access control panel system. Extensive man-machine testing with prototype mock-ups was conducted to assess human engineered design features and to illuminate potentially confusing or difficult-to-operated hardware placement, layout, and operation sequencing. These evaluations, along with the prototype mock-ups, provided input which resulted in a prototype which was easy to enter, operate, and understand by end users. This prototype later served as the design basis for the final systems design

28 CFR 25.6 - Accessing records in the system.

Science.gov (United States)

2010-07-01

... National Instant Criminal Background Check System § 25.6 Accessing records in the system. (a) FFLs may... through the NCIC communication network. Upon receiving a request for a background check from an FFL, a POC...

Key issues of multiple access technique for LEO satellite communication systems

Institute of Scientific and Technical Information of China (English)

温萍萍; 顾学迈

2004-01-01

The large carrier frequency shift caused by the high-speed movement of satellite (Doppler effects) and the propagation delay on the up-down link are very critical issues in an LEO satellite communication system, which affects both the selection and the implementation of a suitable access method. A Doppler based multiple access technique is used here to control the flow and an MPRMA-HS protocol is proposed for the application in LEO satellite communication systems. The extended simulation trials prove that the proposed scheme seems to be a very promising access method.

CDC STATE System E-Cigarette Legislation - Youth Access

Data.gov (United States)

U.S. Department of Health & Human Services — 1995-2018. Centers for Disease Control and Prevention (CDC). State Tobacco Activities Tracking and Evaluation (STATE) System. E-Cigarette Legislation—Youth Access....

A system for success: BMC Systems Biology, a new open access journal.

Science.gov (United States)

Hodgkinson, Matt J; Webb, Penelope A

2007-09-04

BMC Systems Biology is the first open access journal spanning the growing field of systems biology from molecules up to ecosystems. The journal has launched as more and more institutes are founded that are similarly dedicated to this new approach. BMC Systems Biology builds on the ongoing success of the BMC series, providing a venue for all sound research in the systems-level analysis of biology.

VLBA Observations of Low Luminosity Flat Spectrum Radio Galaxies and BL Lac Objects: Polarisation Properties

Science.gov (United States)

Bondi, M.; Dallacasa, D.; Stanghellini, C.; Marchã, M. J. M.

We obtained two-epoch VLBA observations at 5 GHz of a list of radio galaxies drawn from the 200 mJy sample (Marcha et al. 1996). The objects selected for milli-arcsecond scale observations are classified, on the basis of their optical spectroscopic and polarimetric properties, as BL Lac objects, normal weak line radio galaxies, broad line radio galaxies, and transition objects (those with intermediate properties). We present preliminary results on the radio polarization properties, on the milli-arcsecond scale, of objects with different optical properties and discuss structural variations detected from the two epochs.

A Protective Mechanism for the Access Control System in the Virtual Domain

Institute of Scientific and Technical Information of China (English)

Jinan Shen; Deqing Zou; Hai Jin; Kai Yang; Bin Yuan; Weiming Li

2016-01-01

In traditional framework,mandatory access control (MAC) system and malicious software are run in kernel mode.Malicious software can stop MAC systems to be started and make it do invalid.This problem cannot be solved under the traditional framework if the operating system (OS) is comprised since malwares are running in ring0 level.In this paper,we propose a novel way to use hypervisors to protect kernel integrity and the access control system in commodity operating systems.We separate the access control system into three parts:policy management (PM),security server (SS) and policy enforcement (PE).Policy management and the security server reside in the security domain to protect them against malware and the isolation feather of the hypervisor can protect them from attacks.We add an access vector cache (AVC) between SS and PE in the guest OS,in order to speed up communication between the guest OS and the security domain.The policy enforcement module is retained in the guest OS for performance.The security of AVC and PE can be ensured by using a memory protection mechanism.The goal of protecting the OS kemel is to ensure the security of the execution path.We implement the system by a modified Xen hypervisor.The result shows that we can secure the security of the access control system in the guest OS with no overhead compared with modules in the latter.Our system offers a centralized security policy for virtual domains in virtual machine environments.

Database application research in real-time data access of accelerator control system

International Nuclear Information System (INIS)

Chen Guanghua; Chen Jianfeng; Wan Tianmin

2012-01-01

The control system of Shanghai Synchrotron Radiation Facility (SSRF) is a large-scale distributed real-time control system, It involves many types and large amounts of real-time data access during the operating. Database system has wide application prospects in the large-scale accelerator control system. It is the future development direction of the accelerator control system, to replace the differently dedicated data structures with the mature standardized database system. This article discusses the application feasibility of database system in accelerators based on the database interface technology, real-time data access testing, and system optimization research and to establish the foundation of the wide scale application of database system in the SSRF accelerator control system. Based on the database interface technology, real-time data access testing and system optimization research, this article will introduce the application feasibility of database system in accelerators, and lay the foundation of database system application in the SSRF accelerator control system. (authors)

A cryogenic monitor system for the Liquid Argon Calorimeter in the SLD detector

International Nuclear Information System (INIS)

Fox, M.J.; Fox, J.D.

1988-10-01

This paper describes the monitoring electronics system design for the Liquid Argon Calorimeter (LAC) portion of the SLD detector. This system measures temperatures and liquid levels inside the LAC cryostat and transfers the results over a fiber-optic serial link to an external monitoring computer. System requirements, unique design constraints, and detailed analog, digital and software designs are presented. Fault tolerance and the requirement for a single design to work in several different operating environments are discussed. 4 refs., 3 figs., 1 tab

Interplay of protein and DNA structure revealed in simulations of the lac operon.

Directory of Open Access Journals (Sweden)

Luke Czapla

Full Text Available The E. coli Lac repressor is the classic textbook example of a protein that attaches to widely spaced sites along a genome and forces the intervening DNA into a loop. The short loops implicated in the regulation of the lac operon suggest the involvement of factors other than DNA and repressor in gene control. The molecular simulations presented here examine two likely structural contributions to the in-vivo looping of bacterial DNA: the distortions of the double helix introduced upon association of the highly abundant, nonspecific nucleoid protein HU and the large-scale deformations of the repressor detected in low-resolution experiments. The computations take account of the three-dimensional arrangements of nucleotides and amino acids found in crystal structures of DNA with the two proteins, the natural rest state and deformational properties of protein-free DNA, and the constraints on looping imposed by the conformation of the repressor and the orientation of bound DNA. The predicted looping propensities capture the complex, chain-length-dependent variation in repression efficacy extracted from gene expression studies and in vitro experiments and reveal unexpected chain-length-dependent variations in the uptake of HU, the deformation of repressor, and the folding of DNA. Both the opening of repressor and the presence of HU, at levels approximating those found in vivo, enhance the probability of loop formation. HU affects the global organization of the repressor and the opening of repressor influences the levels of HU binding to DNA. The length of the loop determines whether the DNA adopts antiparallel or parallel orientations on the repressor, whether the repressor is opened or closed, and how many HU molecules bind to the loop. The collective behavior of proteins and DNA is greater than the sum of the parts and hints of ways in which multiple proteins may coordinate the packaging and processing of genetic information.

Interplay of protein and DNA structure revealed in simulations of the lac operon.

Science.gov (United States)

Czapla, Luke; Grosner, Michael A; Swigon, David; Olson, Wilma K

2013-01-01

The E. coli Lac repressor is the classic textbook example of a protein that attaches to widely spaced sites along a genome and forces the intervening DNA into a loop. The short loops implicated in the regulation of the lac operon suggest the involvement of factors other than DNA and repressor in gene control. The molecular simulations presented here examine two likely structural contributions to the in-vivo looping of bacterial DNA: the distortions of the double helix introduced upon association of the highly abundant, nonspecific nucleoid protein HU and the large-scale deformations of the repressor detected in low-resolution experiments. The computations take account of the three-dimensional arrangements of nucleotides and amino acids found in crystal structures of DNA with the two proteins, the natural rest state and deformational properties of protein-free DNA, and the constraints on looping imposed by the conformation of the repressor and the orientation of bound DNA. The predicted looping propensities capture the complex, chain-length-dependent variation in repression efficacy extracted from gene expression studies and in vitro experiments and reveal unexpected chain-length-dependent variations in the uptake of HU, the deformation of repressor, and the folding of DNA. Both the opening of repressor and the presence of HU, at levels approximating those found in vivo, enhance the probability of loop formation. HU affects the global organization of the repressor and the opening of repressor influences the levels of HU binding to DNA. The length of the loop determines whether the DNA adopts antiparallel or parallel orientations on the repressor, whether the repressor is opened or closed, and how many HU molecules bind to the loop. The collective behavior of proteins and DNA is greater than the sum of the parts and hints of ways in which multiple proteins may coordinate the packaging and processing of genetic information.

Largemouth bass (Micropterus salmoides Lacépède: reproduction management and larval rearing in Italy

Directory of Open Access Journals (Sweden)

A. Dees

2010-01-01

Full Text Available Micropterus salmoides (Lacépède was originally present into the waters of the eastern United States of America, northern Mexico and southern Canada. This species can be distinguished from the other black basses by the fact that its mouth extends to and beyond the edge of the eye and the first and the second dorsal fins are almost separated by a deep dip and there are no scales on the soft rayed of the second dorsal fin.

Croissance et alimentation des larves de corégones (Coregonus lavaretus dans le lac d'Annecy de mars à avril 1996

Directory of Open Access Journals (Sweden)

CRETENOY L.

1997-04-01

Full Text Available La capture de plus de 400 larves de Coregonus lavaretus à 7 dates différentes dans le lac d'Annecy de mars à avril 1996 a permis d'étudier conjointement leur croissance et l'évolution de leur régime alimentaire. Les larves capturées ont une taille comprise entre 8,5 et 20 mm et un stade larvaire allant de 0 à 4, ces deux paramètres étant fortement liés. À mesure qu'elles grandissent, les larves qui consomment d'abord préférentiellement les stades larvaires des copépodes, puis leurs stades adultes, se nourrissent ensuite majoritairement de cladocères. La comparaison des structures de taille des proies ingérées et du zooplancton présent dans le lac conduit à évoquer la notion d'expérience acquise par les larves pour expliquer cette dérive alimentaire.

Considering User's Access Pattern in Multimedia File Systems

Science.gov (United States)

Cho, KyoungWoon; Ryu, YeonSeung; Won, Youjip; Koh, Kern

2002-12-01

Legacy buffer cache management schemes for multimedia server are grounded at the assumption that the application sequentially accesses the multimedia file. However, user access pattern may not be sequential in some circumstances, for example, in distance learning application, where the user may exploit the VCR-like function(rewind and play) of the system and accesses the particular segments of video repeatedly in the middle of sequential playback. Such a looping reference can cause a significant performance degradation of interval-based caching algorithms. And thus an appropriate buffer cache management scheme is required in order to deliver desirable performance even under the workload that exhibits looping reference behavior. We propose Adaptive Buffer cache Management(ABM) scheme which intelligently adapts to the file access characteristics. For each opened file, ABM applies either the LRU replacement or the interval-based caching depending on the Looping Reference Indicator, which indicates that how strong temporally localized access pattern is. According to our experiment, ABM exhibits better buffer cache miss ratio than interval-based caching or LRU, especially when the workload exhibits not only sequential but also looping reference property.

40 CFR 265.34 - Access to communications or alarm system.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Access to communications or alarm system. 265.34 Section 265.34 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID..., STORAGE, AND DISPOSAL FACILITIES Preparedness and Prevention § 265.34 Access to communications or alarm...

System Hardening Architecture for Safer Access to Critical Business ...

African Journals Online (AJOL)

System Hardening Architecture for Safer Access to Critical Business Data. ... and the threat is growing faster than the potential victims can deal with. ... in this architecture are applied to the host, application, operating system, user, and the ...

CDC STATE System E-Cigarette Legislation - Youth Access

Data.gov (United States)

U.S. Department of Health & Human Services — 1995-2017. Centers for Disease Control and Prevention (CDC). State Tobacco Activities Tracking and Evaluation (STATE) System. E-Cigarette Legislation—Youth Access....

Digestibilidade e metabólitos sanguíneos de vacas da raça Holandesa superovuladas que receberam Lac100® ou linhaça em grão como fontes de gordura Digestibility and blood concentration of metabolites in superovulated dairy cows fed Lac100® or linseed as fat sources

Directory of Open Access Journals (Sweden)

F.L.B. Cavalieri

2009-08-01

Full Text Available Foram avaliados os efeitos de duas fontes de gordura, Lac100® (Yakult, fonte de ácido graxo ômega-6, e linhaça em grão (Linum usitatissimum (LIN, fonte de ácido graxo ômega-3, sobre a digestibilidade aparente da matéria seca (DMS, proteína bruta (DPB, fibra em detergente neutro (DFDN, fibra em detergente ácido (DFDA e extrato etéreo (DEE, e concentrações sanguíneas de HDL, LDL, VLDL, colesterol, triglicerídeos, glicose, cálcio, fósforo, N-ureico e progesterona. Foram utilizadas 10 vacas da raça Holandesa em lactação, distribuídas nos dois tratamentos, em um delineamento estatístico inteiramente casualizado. Os animais alimentados com Lac100® apresentaram maiores valores de DFDN (57,44% vs. 50,80% e DEE (77,70% vs. 72,18% quando comparados aos alimentados com LIN. Os animais alimentados com Lac100® apresentaram maiores concentrações de LDL (111,00 vs. 45,46mg/dL, HDL (82,27 vs. 64,93mg/dL e colesterol total (203,60 vs. 116,13mg/dL e menor concentração de N-ureico (13,22 vs. 15,19mg/dL em relação aos animais alimentados com linhaça em grão. As concentrações sanguíneas de glicose, cálcio, fósforo e progesterona não foram alteradas. Os resultados sugerem que a fonte de gordura na dieta modifica a DFDN e a DEE e, as concentrações sanguíneas de LDL, HDL e colesterol total em vacas em lactação.The effect of two sources of fat, calcium salts of soybean oil, Lac100® (Yakult, a source of omega-6 fatty acids or whole flaxseed (Linum usitatissiumum, a source of omega-3 fatty acids were evaluated to determine the apparent digestibility of dry matter (DDM, crude protein (DCP, neutral detergent fiber (DNDF, acid detergent fiber (DADF, and ether extract (DEE; and blood concentrations of HDL, LDL, VLDL, cholesterol, triglycerides, glucose, calcium, phosphorus, N-urea, and progesterone. Ten lactating Holstein cows were allocated in two treatments and a completely randomized design was used. Cows fed Lac100® had higher

Multi-epoch intranight optical monitoring of eight radio-quiet BL Lac candidates

Science.gov (United States)

Kumar, P.; Gopal-Krishna; Stalin, C. S.; Chand, H.; Srianand, R.; Petitjean, P.

2017-10-01

For a new sample of eight weak-line quasars (WLQs) we report a sensitive search in 20 intranight monitoring sessions, for blazar-like optical flux variations on hour-like and longer time-scale (day/month/year-like). The sample consists exclusively of the WLQs that are not radio-loud and either have been classified as 'radio-weak probable BL Lac candidates' and/or are known to have exhibited at least one episode of large, blazar-like optical variability. Whereas only a hint of intranight variability is seen for two of these WLQs, J104833.5+620305.0 (z = 0.219) and J133219.6+622715.9 (z = 3.15), statistically significant internight variability at a few per cent level is detected for three of the sources, including the radio-intermediate WLQ J133219.6+622715.9 (z = 3.15) and the well-known bona fide radio-quiet WLQs J121221.5+534128.0 (z = 3.10) and WLQ J153259.9-003944.1 (z = 4.62). In the rest frame, this variability is intraday and in the far-ultraviolet band. On the time-scale of a decade, we find for three of the WLQs large brightness changes, amounting to 1.655 ± 0.009, 0.163 ± 0.010 and 0.144 ± 0.018 mag, for J104833.5+620305.0, J123743.1+630144.9 and J232428.4+144324.4, respectively. Whereas the latter two are confirmed radio-quiet WLQs, the extragalactic nature of J104833.5+620305.0 remains to be well established, thanks to the absence of any feature(s) in its available optical spectra. This study forms a part of our ongoing campaign of intranight optical monitoring of radio-quiet WLQs, in order to improve the understanding of this enigmatic class of active galactic nuclei and to look among them for a possible tiny, elusive population of radio-quiet BL Lacs.

General Controls Over the Electronic Document Access System

National Research Council Canada - National Science Library

2000-01-01

...) system as part of the DoD Paper-Free Contracting Initiative. EDA contributes to the initiative by digitizing paper documents and offering web-based read-only access to official contracting, finance and accounting documents...

Automated biometric access control system for two-man-rule enforcement

International Nuclear Information System (INIS)

Holmes, J.P.; Maxwell, R.L.; Henderson, R.W.

1991-01-01

This paper describes a limited access control system for nuclear facilities which makes use of the eye retinal identity verifier to control the passage of personnel into and out of one or a group of security controlled working areas. This access control system requires no keys, cards or credentials. The user simply enters his Personal Identification Number (PIN) and takes an eye reading to request passage. The PIN does not have to be kept secret. The system then relies on biometric identity verification of the user, along with other system information, to make the decision of whether or not to unlock the door. It also enforces multiple zones control with personnel tracking and the two-man-rule

RFID-Based Monitoring And Access Control System For Parliamentary Campus

Directory of Open Access Journals (Sweden)

Sai Thu Rein Htun

2015-08-01

Full Text Available This paper is to implement monitoring and access control system based on RFID and Zigbee technology which can be used at Parliamentary Campus. Nowadays RFID technology is widely used for access control system because it is cheap waterproof and easy to use as well as it contains unique EPC electronic protect code .In addition Zigbee wireless module is cost-effective and can be reliable for security. Sothis system consists of RFID tag RFID reader Arduino Uno and Zigbee. This system can also be used for industrial amp commercial and security HVAC closures. This paper describes the results of point-to-point connection and point-to-multipoint connection using Zigbee and RFID technology.

Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum.

Science.gov (United States)

Allen, Jeremy P; Hathway, Gareth J; Clarke, Neil J; Jowett, Mike I; Topps, Stephanie; Kendrick, Keith M; Humphrey, Patrick P A; Wilkinson, Lawrence S; Emson, Piers C

2003-05-01

The peptide somatostatin can modulate the functional output of the basal ganglia. The exact sites and mechanisms of this action, however, are poorly understood, and the physiological context in which somatostatin acts is unknown. Somatostatin acts as a neuromodulator via a family of five 7-transmembrane G protein-coupled receptors, SSTR1-5, one of which, SSTR2, is known to be functional in the striatum. We have investigated the role of SSTR2 in basal ganglia function using mice in which Sstr2 has been inactivated and replaced by the lacZ reporter gene. Analysis of Sstr2lacZ expression in the brain by beta-galactosidase histochemistry demonstrated a widespread pattern of expression. By comparison to previously published in situ hybridization and immunohistochemical data, Sstr2lacZ expression was shown to accurately recapitulate that of Sstr2 and thus provided a highly sensitive model to investigate cell-type-specific expression of Sstr2. In the striatum, Sstr2 expression was identified in medium spiny projection neurons restricted to the matrix compartment and in cholinergic interneurons. Sstr2 expression was not detected in any other nuclei of the basal ganglia except for a sparse number of nondopaminergic neurons in the substantia nigra. Microdialysis in the striatum showed Sstr2-null mice were selectively refractory to somatostatin-induced dopamine and glutamate release. In behavioural tests, Sstr2-null mice showed normal levels of locomotor activity and normal coordination in undemanding tasks. However, in beam-walking, a test of fine motor control, Sstr2-null mice were severely impaired. Together these data implicate an important neuromodulatory role for SSTR2 in the striatum.

Mutagenesis of the lac promoter region in M13 mp10 phage DNA by 4'-hydroxymethyl-4,5',8-trimethylpsoralen

International Nuclear Information System (INIS)

Piette, J.; Decuyper-Debergh, D.; Gamper, H.

1985-01-01

Double-stranded M13 phage DNA (M13 mp10 replicative form) was photoreacted with 4'-hydroxymethyl-4,5',8-trimethylpsoralen, using light of wavelength greater than 320 nm or greater than 390 nm to generate predominantly crosslinks or monoadducts, respectively. The damaged DNAs were scored for inactivation and mutagenesis after transfection into Escherichia coli. The appearance of light-blue or colorless plaques on indicator medium showed that mutation had occurred in the lac insert of the viral DNA. A comparison of the consequences of the two phototreatments with psoralen supports the idea that crosslinks are both more lethal and more mutagenic than monoadducts. Numerous mutant clones partially or totally deficient in beta-galactosidase were plaque-purified and amplified. The viral DNA of each clone was sequenced by the dideoxy chain-terminating procedure. All of the observed base-pair changes were mapped to the lac promoter region and consisted of 3 transition, 14 transversion, and 6 single base-pair frame-shift mutations. The predominant mutation was a T.A----G.C transversion

Fast Access Data Acquisition System (FADAS)

International Nuclear Information System (INIS)

Katsman, Vladimir

1998-01-01

Our goal in this program is to develop Fast Access Data Acquisition System (FADAS) by combining the flexibility of Multilink's GaAs and InP electronics and electro-optics with an extremely high data rate for the efficient handling and transfer of collider experimental data. This novel solution is based on Multilink's and Los Alamos National Laboratory's (LANL) unique components and technologies for extremely fast data transfer, storage, and processing

Access Safety Systems – New Concepts from the LHC Experience

CERN Document Server

Ladzinski, T; di Luca, S; Hakulinen, T; Hammouti, L; Riesco, T; Nunes, R; Ninin, P; Juget, J-F; Havart, F; Valentini, F; Sanchez-Corral Mena, E

2011-01-01

The LHC Access Safety System has introduced a number of new concepts into the domain of personnel protection at CERN. These can be grouped into several categories: organisational, architectural and concerning the end-user experience. By anchoring the project on the solid foundations of the IEC 61508/61511 methodology, the CERN team and its contractors managed to design, develop, test and commission on time a SIL3 safety system. The system uses a successful combination of the latest Siemens redundant safety programmable logic controllers with a traditional relay logic hardwired loop. The external envelope barriers used in the LHC include personnel and material access devices, which are interlocked door-booths introducing increased automation of individual access control, thus removing the strain from the operators. These devices ensure the inviolability of the controlled zones by users not holding the required credentials. To this end they are equipped with personnel presence detectors and th...

Upper bound for energy efficiency in multi-cell fibre-wireless access systems

NARCIS (Netherlands)

Koonen, A.M.J.; Popov, M.; Wessing, H.

2013-01-01

Bringing radio access points closer to the end-users improves radio energy efficiency. However, taking into account both the radio and the optical parts of a fibre-wireless access system, the overall system energy efficiency has an upper bound determined by the relation between the energy

Upper bound for energy efficiency in multi-cell fibre-wireless access systems

DEFF Research Database (Denmark)

Koonen, A.M.J.; Popov, M.; Wessing, Henrik

2013-01-01

Bringing radio access points closer to the end-users improves radio energy efficiency. However, taking into account both the radio and the optical parts of a fibre-wireless access system, the overall system energy efficiency has an upper bound determined by the relation between the energy...

28 CFR 16.74 - Exemption of National Security Division Systems-limited access.

Science.gov (United States)

2010-07-01

... National Security Division Systems—limited access. (a) The following system of records is exempted from... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Exemption of National Security Division Systems-limited access. 16.74 Section 16.74 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR...

Spectroscopy of 10 γ -Ray BL Lac Objects at High Redshift

Energy Technology Data Exchange (ETDEWEB)

Paiano, Simona; Falomo, Renato [INAF, Osservatorio Astronomico di Padova, Vicolo dell’Osservatorio 5, I-35122 Padova (Italy); Landoni, Marco [INAF, Osservatorio Astronomico di Brera, Via E. Bianchi 46, I-23807 Merate (Italy); Treves, Aldo [Università degli Studi dell’Insubria, Via Valleggio 11, I-22100 Como (Italy); Scarpa, Riccardo [Instituto de Astrofisica de Canarias, C/O Via Lactea, s/n E-38205 La Laguna, Tenerife (Spain)

2017-08-01

We present optical spectra with high signal-to-noise ratio of 10 BL Lac objects detected at GeV energies by the Fermi satellite (3FGL catalog), which previous observations suggested are at relatively high redshift. The new observations, obtained at the 10 m Gran Telescopio Canarias, allowed us to find the redshift for J0814.5+2943 ( z = 0.703), and we can set a spectroscopic lower limit for J0008.0+4713 ( z > 1.659) and J1107.7+0222 ( z > 1.0735) on the basis of Mg ii intervening absorption features. In addition we confirm the redshifts for J0505.5+0416 ( z = 0.423) and J1450+5200 ( z > 2.470). Finally we contradict the previous z estimates for five objects (J0049.7+0237, J0243.5+7119, J0802.0+1005, J1109.4+2411, and J2116.1+3339).

Role of radiation therapy in bladder cancer in the Saguenay-Lac Saint-Jean area

International Nuclear Information System (INIS)

Brochet, F.; Barrette, L.R.

1998-01-01

Bladder cancer is more frequent in Quebec, especially in Saguenay-Lac Saint-Jean than in other Canadian provinces and in the USA. From 1983 to 1996, only 78 patients presenting with bladder cancer received external beam radiation therapy. Sixty-eight were treated with curative intent Overall survival rates were 70% at 3 years, 66% at 5 years, and 40% at 10 years. Retrospective analysis of these cases and literature review show that preoperative radiation therapy is useful in the management of bladder cancer, especially in T3 tumors. It is also useful for patients whose tumor objectively responds to radiation therapy, without an increase in morbidity. (authors)

Analysis of spontaneous deletions and gene amplification in the lac region of Escherichia coli

International Nuclear Information System (INIS)

Albertini, A.M.; Hofer, M.; Calos, M.P.; Tlsty, T.D.; Miller, J.H.

1983-01-01

Spontaneous rearrangements, such as large deletions and duplications, have important implications for the structure of the genome. It is therefore of great interest to analyze these events at the molecular level. We have constructed derivatives of a lacI-Z fusion strain, which allow us to study deletions in a more systematic manner than was previously possible. These derivatives have been used to investigate how frequently larger deletions (> 700 bp) occur between short homologies on both recA and recA - strains and to determine the effect of the lengths of the short homologies and of the distance between homologies on the frequency of deletion formation. 38 references, 11 figures

Geology and age of the Lac a la Perdrix fenite, southern Gatineau district, Quebec

International Nuclear Information System (INIS)

Hogarth, D.D.

1996-01-01

The Lac a Ia Perdrix fenite lies in the Central Metasedimentary Belt of the Grenville Province. This 30 m wide fenite, adjacent to a narrow calciocarbonatite sill, replaces diopside-oligoclase gneiss and is composed of magnesio-arfvedsonite, aegirine, microcline, albite, and fluorapatite. Near the contact with carbonatite, it contains appreciable monazite and barite whereas aegirine virtually disappears. Fenitization probably took place early in the igneous stage of carbonatite development. A Pb/U monazite age of 1026 ± 2 Ma is thought to date fenite formation. Together with published data, this age shows that carbonatite intruded metamorphic rocks near the close of the Grenville Orogeny. (author). 33 refs., 4 tabs., 5 figs

Geology and age of the Lac a la Perdrix fenite, southern Gatineau district, Quebec

Energy Technology Data Exchange (ETDEWEB)

Hogarth, D D [Ottawa Univ., ON (Canada). Dept. of Geology; VanBreemen, O [Geological Survey of Canada, Ottawa, ON (Canada)

1997-12-31

The Lac a Ia Perdrix fenite lies in the Central Metasedimentary Belt of the Grenville Province. This 30 m wide fenite, adjacent to a narrow calciocarbonatite sill, replaces diopside-oligoclase gneiss and is composed of magnesio-arfvedsonite, aegirine, microcline, albite, and fluorapatite. Near the contact with carbonatite, it contains appreciable monazite and barite whereas aegirine virtually disappears. Fenitization probably took place early in the igneous stage of carbonatite development. A Pb/U monazite age of 1026 {+-} 2 Ma is thought to date fenite formation. Together with published data, this age shows that carbonatite intruded metamorphic rocks near the close of the Grenville Orogeny. (author). 33 refs., 4 tabs., 5 figs.

Cardea: Dynamic Access Control in Distributed Systems

Science.gov (United States)

Lepro, Rebekah

2004-01-01

Modern authorization systems span domains of administration, rely on many different authentication sources, and manage complex attributes as part of the authorization process. This . paper presents Cardea, a distributed system that facilitates dynamic access control, as a valuable piece of an inter-operable authorization framework. First, the authorization model employed in Cardea and its functionality goals are examined. Next, critical features of the system architecture and its handling of the authorization process are then examined. Then the S A M L and XACML standards, as incorporated into the system, are analyzed. Finally, the future directions of this project are outlined and connection points with general components of an authorization system are highlighted.

Influence of the salting time on volatile compounds during the manufacture of dry-cured pork shoulder "lacón".

Science.gov (United States)

Purriños, Laura; Franco, Daniel; Carballo, Javier; Lorenzo, José M

2012-12-01

The effect of the length of salting time on volatile compounds throughout the manufacture of dry-cured "lacón" was studied using a purge-and-trap extraction and GC/MS analysis. For this study, six treatments of "lacón" were salted with different amounts of salt (LS (3 days of salting), MS (4 days of salting) and HS (5 days of salting)). The total area of volatile compounds increased significantly (Psalting time increased. Significant differences were found for the total area of all aldehydes for each salting time at the end of process. Hexanal presented the most relative abundance, showing highest content in HS treatments while LS treatments showed the lowest one at the end of salting, post-salting and drying-ripening stage. The influence of salting time on the content of 3-Octen-2-one was significant on salting stage (Psalting time affected (Psalting and at the end of drying-ripening stage. The salting time affected significantly (Psalt level (P>0.05) was detected on total hydrocarbons and total furans at the end of process. Copyright © 2012 Elsevier Ltd. All rights reserved.

A System to Generate SignWriting for Video Tracks Enhancing Accessibility of Deaf People

Directory of Open Access Journals (Sweden)

Elena Verdú

2017-12-01

Full Text Available Video content has increased much on the Internet during last years. In spite of the efforts of different organizations and governments to increase the accessibility of websites, most multimedia content on the Internet is not accessible. This paper describes a system that contributes to make multimedia content more accessible on the Web, by automatically translating subtitles in oral language to SignWriting, a way of writing Sign Language. This system extends the functionality of a general web platform that can provide accessible web content for different needs. This platform has a core component that automatically converts any web page to a web page compliant with level AA of WAI guidelines. Around this core component, different adapters complete the conversion according to the needs of specific users. One adapter is the Deaf People Accessibility Adapter, which provides accessible web content for the Deaf, based on SignWritting. Functionality of this adapter has been extended with the video subtitle translator system. A first prototype of this system has been tested through different methods including usability and accessibility tests and results show that this tool can enhance the accessibility of video content available on the Web for Deaf people.

Prospective evaluation of an internet-linked handheld computer critical care knowledge access system.

Science.gov (United States)

Lapinsky, Stephen E; Wax, Randy; Showalter, Randy; Martinez-Motta, J Carlos; Hallett, David; Mehta, Sangeeta; Burry, Lisa; Stewart, Thomas E

2004-12-01

Critical care physicians may benefit from immediate access to medical reference material. We evaluated the feasibility and potential benefits of a handheld computer based knowledge access system linking a central academic intensive care unit (ICU) to multiple community-based ICUs. Four community hospital ICUs with 17 physicians participated in this prospective interventional study. Following training in the use of an internet-linked, updateable handheld computer knowledge access system, the physicians used the handheld devices in their clinical environment for a 12-month intervention period. Feasibility of the system was evaluated by tracking use of the handheld computer and by conducting surveys and focus group discussions. Before and after the intervention period, participants underwent simulated patient care scenarios designed to evaluate the information sources they accessed, as well as the speed and quality of their decision making. Participants generated admission orders during each scenario, which were scored by blinded evaluators. Ten physicians (59%) used the system regularly, predominantly for nonmedical applications (median 32.8/month, interquartile range [IQR] 28.3-126.8), with medical software accessed less often (median 9/month, IQR 3.7-13.7). Eight out of 13 physicians (62%) who completed the final scenarios chose to use the handheld computer for information access. The median time to access information on the handheld handheld computer was 19 s (IQR 15-40 s). This group exhibited a significant improvement in admission order score as compared with those who used other resources (P = 0.018). Benefits and barriers to use of this technology were identified. An updateable handheld computer system is feasible as a means of point-of-care access to medical reference material and may improve clinical decision making. However, during the study, acceptance of the system was variable. Improved training and new technology may overcome some of the barriers we

Return Migrants’ Experience of Access to Care in Corrupt Healthcare Systems

DEFF Research Database (Denmark)

Handlos, Line Neerup; Olwig, Karen Fog; Bygbjerg, Ib Christian

2016-01-01

unstudied, even though return migrants may be particularly vulnerable to problems related to corruption due to their period of absence from their country of origin. This article investigates how corruption in the healthcare sector affects access to healthcare for refugees who repatriated to Bosnia......Equal and universal access to healthcare services is a core priority for a just health system. A key societal determinant seen to create inequality in access to healthcare is corruption in the healthcare system. How return migrants’ access to healthcare is affected by corruption is largely......, a country with a high level of corruption, from Denmark, a country with a low level of corruption. The study is based on 18 semi-structured interviews with 33 refugees who returned after long-term residence in Denmark. We found that the returned refugees faced greater problems with corruption than...

An Information System to Access Status Information of the LHCb Online

International Nuclear Information System (INIS)

Frank, M; Gaspar, C

2012-01-01

The LHCb collaboration consists of roughly 700 physicists from 52 institutes and universities. Most of the collaborating physicists - including subdetector experts - are not permanently based at CERN. This paper describes the architecture used to publish data internal to the LHCb experiment control- and data acquisition system to the World Wide Web. Collaborators can access the online (sub-) system status and the system performance directly from the institute abroad, from home or from a smart phone without the need of direct access to the online computing infrastructure.

Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY

DEFF Research Database (Denmark)

Mirza, Osman Asghar; Guan, Lan; Verner, Gill

2006-01-01

Cation-coupled active transport is an essential cellular process found ubiquitously in all living organisms. Here, we present two novel ligand-free X-ray structures of the lactose permease (LacY) of Escherichia coli determined at acidic and neutral pH, and propose a model for the mechanism...... of coupling between lactose and H+ translocation. No sugar-binding site is observed in the absence of ligand, and deprotonation of the key residue Glu269 is associated with ligand binding. Thus, substrate induces formation of the sugar-binding site, as well as the initial step in H+ transduction....

On the Protection of Personal Data in the Access Control System

Directory of Open Access Journals (Sweden)

A. P. Durakovskiy

2012-03-01

Full Text Available The aim is to prove the qualification system of access control systems (ACS as an information system for personal data (ISPDn. Applications: systems of physical protection of facilities.

A System for Web-based Access to the HSOS Database

Science.gov (United States)

Lin, G.

Huairou Solar Observing Station's (HSOS) magnetogram and dopplergram are world-class instruments. Access to their data has opened to the world. Web-based access to the data will provide a powerful, convenient tool for data searching and solar physics. It is necessary that our data be provided to users via the Web when it is opened to the world. In this presentation, the author describes general design and programming construction of the system. The system will be generated by PHP and MySQL. The author also introduces basic feature of PHP and MySQL.

An Efficient Role and Object Based Access Control Model Implemented in a PDM System

Institute of Scientific and Technical Information of China (English)

HUANG Xiaowen; TAN Jian; HUANG Xiangguo

2006-01-01

An effective and reliable access control is crucial to a PDM system. This article has discussed the commonly used access control models, analyzed their advantages and disadvantages, and proposed a new Role and Object based access control model that suits the particular needs of a PDM system. The new model has been implemented in a commercial PDM system, which has demonstrated enhanced flexibility and convenience.

Cognitive radio networks medium access control for coexistence of wireless systems

CERN Document Server

Bian, Kaigui; Gao, Bo

2014-01-01

This book gives a comprehensive overview of the medium access control (MAC) principles in cognitive radio networks, with a specific focus on how such MAC principles enable different wireless systems to coexist in the same spectrum band and carry out spectrum sharing.  From algorithm design to the latest developments in the standards and spectrum policy, readers will benefit from leading-edge knowledge of how cognitive radio systems coexist and share spectrum resources.  Coverage includes cognitive radio rendezvous, spectrum sharing, channel allocation, coexistence in TV white space, and coexistence of heterogeneous wireless systems.   • Provides a comprehensive reference on medium access control (MAC)-related problems in the design of cognitive radio systems and networks; • Includes detailed analysis of various coexistence problems related to medium access control in cognitive radio networks; • Reveals novel techniques for addressing the challenges of coexistence protocol design at a higher level ...

ANTI-CORRELATED OPTICAL FLUX AND POLARIZATION VARIABILITY IN BL LAC

Energy Technology Data Exchange (ETDEWEB)

Gaur, Haritma [Inter-University Centre for Astronomy and Astrophysics (IUCAA), Ganeshkhind, Pune 411 007 (India); Gupta, Alok C. [Aryabhatta Research Institute of Observational Sciences (ARIES), Manora Peak, Nainital 263 129 (India); Wiita, Paul J. [Department of Physics, The College of New Jersey, P.O. Box 7718, Ewing, NJ 08628-0718 (United States); Uemura, Makoto; Itoh, Ryosuke; Sasada, Mahito, E-mail: haritma@iucaa.ernet.in [Hiroshima Astrophysical Science Center, Hiroshima University, Kagamiyama 1-3-1, Higashi-Hiroshima 739-8526 (Japan)

2014-01-20

We present the results of photometric (V band) and polarimetric observations of the blazar BL Lac during 2008-2010 using TRISPEC attached to the KANATA 1.5 m telescope in Japan. The data reveal a great deal of variability ranging from days to months with detection of strong variations in fractional polarization. The V band flux strongly anticorrelates with the degree of polarization during the first of two observing seasons but not during the second. The direction of the electric vector, however, remained roughly constant during all of our observations. These results are consistent with a model with at least two emission regions being present, with the more variable component having a polarization direction nearly perpendicular to that of the relatively quiescent region so that a rising flux can produce a decline in degree of polarization. We also computed models involving helical jet structures and single transverse shocks in jets and show that they might also be able to agree with the anticorrelations between flux and fractional polarization.

Access to justice in the Convention on Rights system

NARCIS (Netherlands)

Gerards, J.H.; Glas, L.R.

2017-01-01

The numerous reforms to the Convention system of the past two decades have unquestionably had an effect on applicants’ means to access justice in the system. It is, however, open to question how these changes should be evaluated: with reference to the individual right to petition, or with reference

Spatial and Temporal Variations in Diatoms from la Chaine des Lacs Urban Watershed, Nord-Pas France, in Relation to Water Quality

Science.gov (United States)

Noble, P. J.; Van de Vijver, B.; Verleyen, E.; Prygiel, J.; Ivanovsky, A.; Lesven, L.; Billon, G.

2016-12-01

Diatom analysis was conducted on lake sediments in la Chaîne des Lacs (CDL), a shallow eutrophic urban park and storm control system in Villeneuve d'Ascq, France, to address both the present day water quality, and the evolution of this urban system over its 40 year history. The main lake, Lac du Héron (LDH), received recent attention because of water quality problems, including eutrophication, harmful algal blooms, and invasion by the macrophyte Elodea in 2012. A total of 17 sites were collected in CDL, 11 of which were in LDH, to document spatial variability, and a 26cm long core addresses historical changes. The bulk of the diatom assemblage in LDH can be classified as both eutrophic and moderately metal tolerant, using modern national diatom indices developed and used by the French regional water agencies. Surface sediment samples within LDH show large spatial variations in %Cocconeis placentula whose habitat is epiphytic growth on Elodea. Other variation is reflected in the phytoplankton composition both spatially, and interannually. Aulacoseira muzzanensis and Cyclostephanos dubius showed greater abundance in the open water habitats in LDH, whereas sites in CDL outside of LDH had greater Cyclotella meneghiniana. Temporally, Stephanodicsus (largely S. hantzschii), the dominant diatom in early spring, were present in greater abundances in the 2016 surface sediment samples than in any of the 2015 samples. One possible explanation is that the 2016 samples, taken March 30th, preferentially preserved the early spring Stephanodiscus bloom, in contrast to the 2015 samples, which were taken in January. The sediment core provides an historical record, where the uppermost 4cm plot with the bulk of the LDH surface samples and contain abundant Cocconeis, 4 -14cm is phytoplankton-rich, largely Cyclostephanos dubius and Aulacoseira muzzanensis, and represents a less weed-choked environment prior to the 2012 Elodea invasion. The base of the core is dominated by Amphora and

Assessment of Deafblind Access to Manual Language Systems (ADAMLS)

Science.gov (United States)

Blaha, Robbie; Carlson, Brad

2007-01-01

This document presents the Assessment of Deafblind Access to Manual Language Systems (ADAMLS), a resource for educational teams who are responsible for developing appropriate adaptations and strategies for children who are deafblind who are candidates for learning manual language systems. The assessment tool should be used for all children with a…

Access to essential medicines in Pakistan: policy and health systems research concerns.

Directory of Open Access Journals (Sweden)

Shehla Zaidi

Full Text Available INTRODUCTION: Inadequate access to essential medicines is a common issue within developing countries. Policy response is constrained, amongst other factors, by a dearth of in-depth country level evidence. We share here i gaps related to access to essential medicine in Pakistan; and ii prioritization of emerging policy and research concerns. METHODS: An exploratory research was carried out using a health systems perspective and applying the WHO Framework for Equitable Access to Essential Medicine. Methods involved key informant interviews with policy makers, providers, industry, NGOs, experts and development partners, review of published and grey literature, and consultative prioritization in stakeholder's Roundtable. FINDINGS: A synthesis of evidence found major gaps in essential medicine access in Pakistan driven by weaknesses in the health care system as well as weak pharmaceutical regulation. 7 major policy concerns and 11 emerging research concerns were identified through consultative Roundtable. These related to weaknesses in medicine registration and quality assurance systems, unclear and counterproductive pricing policies, irrational prescribing and sub-optimal drug availability. Available research, both locally and globally, fails to target most of the identified policy concerns, tending to concentrate on irrational prescriptions. It overlooks trans-disciplinary areas of policy effectiveness surveillance, consumer behavior, operational pilots and pricing interventions review. CONCLUSION: Experience from Pakistan shows that policy concerns related to essential medicine access need integrated responses across various components of the health systems, are poorly addressed by existing evidence, and require an expanded health systems research agenda.

Providers' Access of Imaging Versus Only Reports: A System Log File Analysis.

Science.gov (United States)

Jung, Hye-Young; Gichoya, Judy Wawira; Vest, Joshua R

2017-02-01

An increasing number of technologies allow providers to access the results of imaging studies. This study examined differences in access of radiology images compared with text-only reports through a health information exchange system by health care professionals. The study sample included 157,256 historical sessions from a health information exchange system that enabled 1,670 physicians and non-physicians to access text-based reports and imaging over the period 2013 to 2014. The primary outcome was an indicator of access of an imaging study instead of access of a text-only report. Multilevel mixed-effects regression models were used to estimate the association between provider and session characteristics and access of images compared with text-only reports. Compared with primary care physicians, specialists had an 18% higher probability of accessing actual images instead of text-only reports (β = 0.18; P < .001). Compared with primary care practice settings, the probability of accessing images was 4% higher for specialty care practices (P < .05) and 8% lower for emergency departments (P < .05). Radiologists, orthopedists, and neurologists accounted for 79% of all the sessions with actual images accessed. Orthopedists, radiologists, surgeons, and pulmonary disease specialists accessed imaging more often than text-based reports only. Consideration for differences in the need to access images compared with text-only reports based on the type of provider and setting of care are needed to maximize the benefits of image sharing for patient care. Copyright © 2016 American College of Radiology. Published by Elsevier Inc. All rights reserved.

Development of a wireless protection against imitation system for identification and control of vehicle access

Directory of Open Access Journals (Sweden)

Aleksei A. Gavrishev

2018-03-01

Full Text Available This article deals with wireless systems for identification and control of vehicle access to protected objects. Known systems are considered. As a result, it has been established that one of the most promising approaches to identifying and controlling vehicle access to protected objects is the use of systems based on the "friend or foe" principle. Among these systems, there are "one-directional" and "bedirectional" identification and access control systems. "Bidirectional" systems are more preferable for questions of identification and access control. However, at present, these systems should have a reduced probability of recognizing the structure of the request and response signals because the potential attacker can easily perform unauthorized access to the radio channel of the system. On this basis, developed a wireless system identification and control vehicle access to protected objects based on the principle of "friend or foe", featuring increased protection from unauthorized access and jamming through the use of rewritable drives chaotic sequences. In addition, it’s proposed to use to identify the vehicle's RFID tag containing additional information about it. Are some specifications of the developed system (the possible frequency range of the request-response signals, the communication range, data rate, the size of the transmitted data, guidelines for choosing RFID. Also, with the help of fuzzy logic, was made the security assessment from unauthorized access request-response signals based on the system of "friend or foe", which are transferred via radio channel, developed systems and analogues. The security assessment of the developed system shows an adequate degree of protection against complex threats (view, spoofing, interception and jamming of traffic in comparison with known systems of this class. Among the main advantages of the developed system it’s necessary to mention increased security from unauthorized access and jamming

Problems and Concerns Regarding Access Control System Construction in Radiation Facilities Based on the NIFS Experience

International Nuclear Information System (INIS)

Kawano, T.; Inoue, N.; Sakuma, Y.; Motojima, O.

2001-01-01

Full text: In 1998, access control system for the large helical device (LHD) experimental hall was constructed and put into operation at the National Institute for Fusion Science (NIFS) in Toki, Japan. Since then, the system has been continuously improved. It now controls access into the LHD controlled area through four entrances. The system has five turnstile gates and enables control of access at the four entrances. The system is always checking whether the shielding doors are open or closed at eight positions. The details pertaining to the construction of the system were reported at IRPA-10 held in Hiroshima, Japan, in 2000. Based on our construction experience of the NIFS access control system, we will discuss problems related to software and operational design of the system. We will also discuss some concerns regarding the use of the system in radiation facilities. The problems we will present concern, among other thing, individual registration, time control, turnstile control, interlock signal control, data aggregation and transactions, automatic and manual control, and emergency procedures. For example, in relation to the time control and turnstile control functions, we will discuss the gate-opening time interval for an access event, the timing of access data recording, date changing, turn bar control, double access, and access error handling. (author)

Data Access System for Hydrology

Science.gov (United States)

Whitenack, T.; Zaslavsky, I.; Valentine, D.; Djokic, D.

2007-12-01

As part of the CUAHSI HIS (Consortium of Universities for the Advancement of Hydrologic Science, Inc., Hydrologic Information System), the CUAHSI HIS team has developed Data Access System for Hydrology or DASH. DASH is based on commercial off the shelf technology, which has been developed in conjunction with a commercial partner, ESRI. DASH is a web-based user interface, developed in ASP.NET developed using ESRI ArcGIS Server 9.2 that represents a mapping, querying and data retrieval interface over observation and GIS databases, and web services. This is the front end application for the CUAHSI Hydrologic Information System Server. The HIS Server is a software stack that organizes observation databases, geographic data layers, data importing and management tools, and online user interfaces such as the DASH application, into a flexible multi- tier application for serving both national-level and locally-maintained observation data. The user interface of the DASH web application allows online users to query observation networks by location and attributes, selecting stations in a user-specified area where a particular variable was measured during a given time interval. Once one or more stations and variables are selected, the user can retrieve and download the observation data for further off-line analysis. The DASH application is highly configurable. The mapping interface can be configured to display map services from multiple sources in multiple formats, including ArcGIS Server, ArcIMS, and WMS. The observation network data is configured in an XML file where you specify the network's web service location and its corresponding map layer. Upon initial deployment, two national level observation networks (USGS NWIS daily values and USGS NWIS Instantaneous values) are already pre-configured. There is also an optional login page which can be used to restrict access as well as providing a alternative to immediate downloads. For large request, users would be notified via

NASA Access Mechanism - Graphical user interface information retrieval system

Science.gov (United States)

Hunter, Judy F.; Generous, Curtis; Duncan, Denise

1993-01-01

Access to online information sources of aerospace, scientific, and engineering data, a mission focus for NASA's Scientific and Technical Information Program, has always been limited by factors such as telecommunications, query language syntax, lack of standardization in the information, and the lack of adequate tools to assist in searching. Today, the NASA STI Program's NASA Access Mechanism (NAM) prototype offers a solution to these problems by providing the user with a set of tools that provide a graphical interface to remote, heterogeneous, and distributed information in a manner adaptable to both casual and expert users. Additionally, the NAM provides access to many Internet-based services such as Electronic Mail, the Wide Area Information Servers system, Peer Locating tools, and electronic bulletin boards.

NASA access mechanism: Graphical user interface information retrieval system

Science.gov (United States)

Hunter, Judy; Generous, Curtis; Duncan, Denise

1993-01-01

Access to online information sources of aerospace, scientific, and engineering data, a mission focus for NASA's Scientific and Technical Information Program, has always been limited to factors such as telecommunications, query language syntax, lack of standardization in the information, and the lack of adequate tools to assist in searching. Today, the NASA STI Program's NASA Access Mechanism (NAM) prototype offers a solution to these problems by providing the user with a set of tools that provide a graphical interface to remote, heterogeneous, and distributed information in a manner adaptable to both casual and expert users. Additionally, the NAM provides access to many Internet-based services such as Electronic Mail, the Wide Area Information Servers system, Peer Locating tools, and electronic bulletin boards.

Additional new species of Hypostomus Lacépède, 1803, from Surinam; with remarks on the apparent „gymnorhynchus-complex” (Siluriformes, Loricariidae)

NARCIS (Netherlands)

Boeseman, M.

1969-01-01

Two new Surinam species of Hypostomus Lacépède are described, and their relationship is discussed; a group of three forms from eastern Surinam and (French) Guyane (gymnorhynchus-complex) is reconsidered; the species H. plecostomus (Linnaeus) is reported to hitherto survive in the lacustrine

Systemic barriers accessing HIV treatment among people who inject drugs in Russia: a qualitative study.

Science.gov (United States)

Sarang, Anya; Rhodes, Tim; Sheon, Nicolas

2013-10-01

Achieving 'universal access' to antiretroviral HIV treatment (ART) in lower income and transitional settings is a global target. Yet, access to ART is shaped by local social condition and is by no means universal. Qualitative studies are ideally suited to describing how access to ART is socially situated. We explored systemic barriers to accessing ART among people who inject drugs (PWID) in a Russian city (Ekaterinburg) with a large burden of HIV treatment demand. We undertook 42 in-depth qualitative interviews with people living with HIV with current or recent experience of injecting drug use. Accounts were analysed thematically, and supplemented here with an illustrative case study. Three core themes were identified: 'labyrinthine bureaucracy' governing access to ART; a 'system Catch 22' created by an expectation that access to ART was conditional upon treated drug use in a setting of limited drug treatment opportunity; and 'system verticalization', where a lack of integration across HIV, tuberculosis (TB) and drug treatment compromised access to ART. Taken together, we find that systemic factors play a key role in shaping access to ART with the potential adverse effects of reproducing treatment initiation delay and disengagement from treatment. We argue that meso-level systemic factors affecting access to ART for PWID interact with wider macro-level structural forces, including those related to drug treatment policy and the social marginalization of PWID. We note the urgent need for systemic and structural changes to improve access to ART for PWID in this setting, including to simplify bureaucratic procedures, foster integrated HIV, TB and drug treatment services, and advocate for drug treatment policy reform.

Quantitative transcript analysis of the inducible expression system pSIP: comparison of the overexpression of Lactobacillus spp. β-galactosidases in Lactobacillus plantarum

Directory of Open Access Journals (Sweden)

Eijsink Vincent GH

2011-06-01

Full Text Available Abstract Background Two sets of overlapping genes, lacLMReu and lacLMAci, encoding heterodimeric β-galactosidases from Lactobacillus reuteri and Lactobacillus acidophilus, respectively, have previously been cloned and expressed using the pSIP vector system and Lactobacillus plantarum WCSF1 as host. Despite the high similarity between these lacLM genes and the use of identical cloning and expression strategies, strains harboring lacLMReu produced about twenty-fold more β-galactosidase than strains containing lacLMAci. Results In this study, the plasmid copy numbers (PCN of expression vectors pEH9R (lacLMReu and pEH9A (lacLMAci as well as the transcription levels of both lacLM genes were compared using quantitative PCR methods. Analyses of parallel fermentations of L. plantarum harboring either pEH9R or pEH9A showed that the expression plasmids were present in similar copy numbers. However, transcript levels of lacLM from L. reuteri (pEH9R were up to 18 times higher than those of lacLM from L. acidophilus (pEH9A. As a control, it was shown that the expression levels of regulatory genes involved in pheromone-induced promoter activation were similar in both strains. Conclusion The use of identical expression strategies for highly similar genes led to very different mRNA levels. The data indicate that this difference is primarily caused by translational effects that are likely to affect both mRNA synthesis rates and mRNA stability. These translational effects thus seem to be a dominant determinant for the success of gene expression efforts in lactobacilli.

Interactive water monitoring system accessible by cordless telephone

Science.gov (United States)

Volpicelli, Richard; Andeweg, Pierre; Hagar, William G.

1985-12-01

A battery-operated, microcomputer-controlled monitoring device linked with a cordless telephone has been developed for remote measurements. This environmental sensor is self-contained and collects and processes data according to the information sent to its on-board computer system. An RCA model 1805 microprocessor forms the basic controller with a program encoded in memory for data acquisition and analysis. Signals from analog sensing devices used to monitor the environment are converted into digital signals and stored in random access memory of the microcomputer. This remote sensing system is linked to the laboratory by means of a cordless telephone whose base unit is connected to regular telephone lines. This offshore sensing system is simply accessed by a phone call originating from a computer terminal in the laboratory. Data acquisition is initiated upon request: Information continues to be processed and stored until the computer is reprogrammed by another phone call request. Information obtained may be recalled by a phone call after the desired environmental measurements are finished or while they are in progress. Data sampling parameters may be reset at any time, including in the middle of a measurement cycle. The range of the system is limited only by existing telephone grid systems and by the transmission characteristics of the cordless phone used as a communications link. This use of a cordless telephone, coupled with the on-board computer system, may be applied to other field studies requiring data transfer between an on-site analytical system and the laboratory.

Performance Analysis of DPSK-OCDMA System for Optical Access Network

Science.gov (United States)

Islam, Monirul; Ahmed, N.; Aljunid, S. A.; Ali, Sharafat; Sayeed, S.; Sabri, Naseer

2016-03-01

In this research, the performance of optical code division multiple access (OCDMA) using differential phase shift keying (DPSK) has been compared with OCDMA On-Off Keying (OOK). This comparison took place in terms of bit error rate (BER) and receiver power where two bit rates (155 Mbps and 622 Mbps) have been used for this analysis. Using of OptiSystem 7.0 simulation, comparing eye diagram and optical spectrum alongside with BER and Rx power. It is found that OCDMA-DPSK performs better in comparison to OCDMA-OOK. The performance analysis also provides parameter for designing and development of an OCDMA system for optical access network using DPSK.

Optimization of lignin peroxidase, manganese peroxidase, and Lac production from Ganoderma lucidum under solid state fermentation of pineapple leaf

OpenAIRE

Sudha Hariharan; Padma Nambisan

2013-01-01

This study was undertaken to isolate ligninase-producing white-rot fungi for use in the extraction of fibre from pineapple leaf agriwaste. Fifteen fungal strains were isolated from dead tree trunks and leaf litter. Ligninolytic enzymes (lignin peroxidase (LiP), manganese peroxidase (MnP), and laccase (Lac)), were produced by solid-state fermentation (SSF) using pineapple leaves as the substrate. Of the isolated strains, the one showing maximum production of ligninolytic enzymes was identified...

A system for success: BMC Systems Biology, a new open access journal

OpenAIRE

Webb Penelope A; Hodgkinson Matt J

2007-01-01

Abstract BMC Systems Biology is the first open access journal spanning the growing field of systems biology from molecules up to ecosystems. The journal has launched as more and more institutes are founded that are similarly dedicated to this new approach. BMC Systems Biology builds on the ongoing success of the BMC series, providing a venue for all sound research in the systems-level analysis of biology.

Email based remote access and surveillance system for smart home infrastructure

Directory of Open Access Journals (Sweden)

Pooshkar Rajiv

2016-09-01

Full Text Available With the rapid rise of Internet of Things in public domain, people expect fast, reliable and on-demand home security via the Internet. However, existing remote home surveillance systems place a very rigid constraint on authentication and require customized hardware and software. In this paper we have proposed an ingenious and reliable internet based, home access system for smart homes that can be easily deployed on generic hardware. The proposed architecture uses popular email service providers to notify and update the user about the home access. It sends an email to the owner with the attached picture of the person who is at the door. It also incorporates a protected mechanism to give access of the door to a remote user by responding to that email. It essentially means that we can view and give access to the person at our door via sending and receiving an email. Furthermore, an image processing based mechanism has also been incorporated to provide access without email, to few selected personnel who are trusted by the owner. It works by capturing and comparing the visitor's image with the stored images in the database. Perceptual hashing or fingerprint matching algorithm is used for comparison purposes. Similarity percentage based on hamming distance was evaluated, and the similarity threshold for providing access was set. The simulations were performed in rigorous environment. The efficiency of the hashing algorithm was found to be 97% at the similarity threshold of 95%. The results validate that the average latency is only 155 ms with low standard deviation. The CPU utilization remained quite low with a minimum value of 10 MHz and a maximum value of 30 MHz when the payload size of the sent mail was increased to 1500 kB. Thus, the proposed system can be used for developing a larger low power infrastructure.

The upgrade of the J-TEXT experimental data access and management system

International Nuclear Information System (INIS)

Yang, C.; Zhang, M.; Zheng, W.; Liu, R.; Zhuang, G.

2014-01-01

Highlights: • The J-TEXT DAMS is developed based on B/S model, which makes it conveniently access the system. • The JWeb-Scope adopts segment strategy to read data that improve the speed of reading data. • DAMS have integrated the management and JWeb-Scope and make an easy way for visitors to access the experiment data. • The JWeb-Scope can be visited all over the world, plot experiment data and zoom in or out smoothly. - Abstract: The experimental data of J-TEXT tokamak are stored in the MDSplus database. The old J-TEXT data access system is based on the tools provided by MDSplus. Since the number of signals is huge, the data retrieval for an experiment is difficult. To solve this problem, the J-TEXT experimental data access and management system (DAMS) based on MDSplus has been developed. The DAMS left the old MDSplus system unchanged providing new tools, which can help users to handle all signals as well as to retrieve signals they need thanks to the user information requirements. The DAMS also offers users a way to create their jScope configuration files which can be downloaded to the local computer. In addition, the DAMS provides a JWeb-Scope tool to visualize the signal in a browser. JWeb-Scope adopts segment strategy to read massive data efficiently. Users can plot one or more signals on their own choice and zoom-in, zoom-out smoothly. The whole system is based on B/S model, so that the users only need of the browsers to access the DAMS. The DAMS has been tested and it has a better user experience. It will be integrated into the J-TEXT remote participation system later

Providing Access to Library Automation Systems for Students with Disabilities.

Science.gov (United States)

California Community Colleges, Sacramento. High-Tech Center for the Disabled.

This document provides information on the integration of assistive computer technologies and library automation systems at California Community Colleges in order to ensure access for students with disabilities. Topics covered include planning, upgrading, purchasing, implementing and using these technologies with library systems. As information…

What systems participants know about access and service entry and why managers should listen.

Science.gov (United States)

Duncombe, Rohena

2017-08-01

Objective The present study looked at the views of people directly involved in the entry process for community health counselling using the frame of the health access literature. The concurrence of system participants' views with the access literature highlights access issues, particularly for people who are vulnerable or disadvantaged. The paper privileges the voices of the system participants, inviting local health services to consider using participatory design to improve access at the entry point. Methods People involved in the entry process for community health counselling explored the question, 'What, for you, are the features of a good intake system?' They also commented on themes identified during pilot interviews. These were thematically analysed for each participant group by the researcher to develop a voice for each stakeholder group. Results People accessing the service could be vulnerable and the entry process failed to take that into account. People directly involved in the counselling service entry system, system participants, consisted of: professionals referring in, people seeking services and reception staff taking first enquiries. They shared substantially the same concerns as each other. The responses from these system participants are consistent with the international literature on access and entry into health services. Conclusion Participatory service design could improve primary healthcare service entry at the local level. Canvassing the experiences of system participants is important for delivering services to those who have the least access and, in that way, could contribute to health equity. What is known about the topic? People with the highest health needs receive the fewest services. Health inequality is increasing. What does this paper add? System participants can provide advice consistent with the academic research literature that is useful for improving service entry at the local level. What are the implications for practitioners

Average opportunity-based accessibility of public transit systems to grocery stores in small urban areas

Directory of Open Access Journals (Sweden)

Nimish Dharmadhikari

2015-12-01

Full Text Available This research studies the accessibility of grocery stores to university students using the public transportation system, drawing from a case study of Fargo, North Dakota. Taking into consideration the combined travel time components of walking, riding, and waiting, this study measures two types of accessibilities: accessibility to reach a particular place and accessibility to reach the bus stop to ride the public transit system. These two accessibilities are interdependent and cannot perform without each other. A new method to calculate the average accessibility measure for the transit routes is proposed. A step-wise case study analysis indicates that one route provides accessibility to a grocery store in eight minutes. This also suggests that the North Dakota State University area has moderate accessibility to grocery stores.

Design and Implementation of a Library and Information Science Open Access Journal Union Catalogue System

Directory of Open Access Journals (Sweden)

Sinn-Cheng Lin

2017-03-01

Full Text Available Open access is a mode of academic communication that has been on the rise in recent years, but open access academic resources are widely dispersed across the internet, making it occasionally inconvenient in terms of its use. This research is focused on library and information science, using the OAIS reference model as the system framework, two open access platform, DOAJ and E-LIS as the data sources, and through system implementation develop a “library and information science open access journal union catalogue” system. Using the OAI-PMH protocol as the data interoperability standard, and LAMP as the development environment, four major functionalities: injest, archiving, management and access of information were designed, developed, and integrated into system build. Actual testing and verification showed this system is able to successfully collect data from DOAJ and E-LIS open journal resources related to library and information science. The system is now active and functional, and can be used by researchers in the library and science information field.

A semi-automated vascular access system for preclinical models

International Nuclear Information System (INIS)

Berry-Pusey, B N; David, J; Taschereau, R; Silverman, R W; Williams, D; Ladno, W; Stout, D; Chatziioannou, A; Chang, Y C; Prince, S W; Chu, K; Tsao, T C

2013-01-01

Murine models are used extensively in biological and translational research. For many of these studies it is necessary to access the vasculature for the injection of biologically active agents. Among the possible methods for accessing the mouse vasculature, tail vein injections are a routine but critical step for many experimental protocols. To perform successful tail vein injections, a high skill set and experience is required, leaving most scientists ill-suited to perform this task. This can lead to a high variability between injections, which can impact experimental results. To allow more scientists to perform tail vein injections and to decrease the variability between injections, a vascular access system (VAS) that semi-automatically inserts a needle into the tail vein of a mouse was developed. The VAS uses near infrared light, image processing techniques, computer controlled motors, and a pressure feedback system to insert the needle and to validate its proper placement within the vein. The VAS was tested by injecting a commonly used radiolabeled probe (FDG) into the tail veins of five mice. These mice were then imaged using micro-positron emission tomography to measure the percentage of the injected probe remaining in the tail. These studies showed that, on average, the VAS leaves 3.4% of the injected probe in the tail. With these preliminary results, the VAS system demonstrates the potential for improving the accuracy of tail vein injections in mice. (paper)

The optimal access system for future far-offshore wind farms

Energy Technology Data Exchange (ETDEWEB)

Obdam, T.S.; Rademakers, L.W.M.M.; Savenije, L.B. [ECN Wind Energy, Petten (Netherlands)

2013-12-15

Operation and maintenance (O and M) of offshore wind turbines is one of the main cost drivers of offshore wind energy. One of the aspects critical for an efficient and cost-effective O and M strategy is the selection of the access system which is used to transfer technicians and, optionally, small spare parts. Currently, most offshore wind farms are located close to shore, and their size is relatively small. For these farms the typical access system consists of catamaran-like workboats, which are used to transfer both technicians and small spare parts. As wind farms move further offshore this O and M concept might no longer be cost-effective. Currently, different alternative O and M concepts are being considered for the future far-offshore sites. In this paper an extensive and holistic comparison of different O and M concepts including different access system solutions is presented. This analysis has been performed using the OMCECalculator, ECN's software for advanced O and M cost modelling. Different sites have been considered, which are typical for the future offshore wind farms that will be commissioned during the next five years. The results of the performed analyses indicate that when moving further offshore harbour-based O and M strategies are no longer economical, even when helicopters are added to the mix. Looking at farm-based O and M concepts a supply vessel with a compensated access gangway offers great potential. However, the calculations also indicate that its ability to transfer small spare parts, in addition to technicians, is crucial.

Asynchronous Free-Space Optical CDMA Communications System for Last-mile Access Network

DEFF Research Database (Denmark)

Jurado-Navas, Antonio; Raddo, Thiago R.; Sanches, Anderson L.

2016-01-01

We propose a new hybrid asynchronous OCDMA-FSO communications system for access network solutions. New ABER expressions are derived under gamma-gamma scintillation channels, where all users can surprisingly achieve error-free transmissions when FEC is employed.......We propose a new hybrid asynchronous OCDMA-FSO communications system for access network solutions. New ABER expressions are derived under gamma-gamma scintillation channels, where all users can surprisingly achieve error-free transmissions when FEC is employed....

Distributed magnetic field positioning system using code division multiple access

Science.gov (United States)

Prigge, Eric A. (Inventor)

2003-01-01

An apparatus and methods for a magnetic field positioning system use a fundamentally different, and advantageous, signal structure and multiple access method, known as Code Division Multiple Access (CDMA). This signal architecture, when combined with processing methods, leads to advantages over the existing technologies, especially when applied to a system with a large number of magnetic field generators (beacons). Beacons at known positions generate coded magnetic fields, and a magnetic sensor measures a sum field and decomposes it into component fields to determine the sensor position and orientation. The apparatus and methods can have a large `building-sized` coverage area. The system allows for numerous beacons to be distributed throughout an area at a number of different locations. A method to estimate position and attitude, with no prior knowledge, uses dipole fields produced by these beacons in different locations.

The design and implementation of access control management system in IHEP network

International Nuclear Information System (INIS)

Wang Yanming; An Dehai; Qi Fazhi

2010-01-01

In campus network environment of Institute of High Energy Physics, because of the number of Network devices and computers are large scale, ensuring the access validity of network devices and user's computer, and aiming at effective control the exceptional network communication are technological means to achieve network normal running. The access control system of Campus network of institute of High Energy Physics using MySQL database in the behind, and using CGI PHP HTML language to develop the front interface. The System achieves user information management, user computer access control, cutting down the exceptional network communication and alarm function. Increasing the management effective of network, to ensure campus network safety and reliable running. (authors)

Isolation and characterization of Tn917lac-generated competence mutants of Bacillus subtilis

International Nuclear Information System (INIS)

Hahn, J.; Albano, M.; Dubnau, D.

1987-01-01

The authors isolated 28 mutants of Bacillus subtilis deficient in the development of competence by using the transposon Tn917lacZ as a mutagen. The mutant strains were poorly transformable with plasmid and chromosomal DNAs but were normally transducible and exhibited wild-type resistance to DNA-damaging agents. The mutations were genetically mapped, and the mutants were characterized with respect to their abilities to bind and take up radiolabeled DNA. All were defective in uptake, and some failed to bind significantly amounts of DNA. The abilities of the mutant strains to resolve into two buoyant density classes on Renografin gradients were studied. Most resolved normally, but several banded in Renografin only at the buoyant density of noncompetent cells. The genetic mapping studies and the other analyses suggested that the mutations define a minimum of seven distinct com genes

Towards Payment Systems for all: accessible POS

Directory of Open Access Journals (Sweden)

Begoña Pino

2014-10-01

Full Text Available The project presented here is a first step towards building a more accessible world through Payment Systems and a successful implementation of a User Centred Design. By means of a beep-system, a Point of Sale (POS payment device informs the user of those transaction steps that require his/her attention at the moment of payment, such as when: the card has been successfully read, the Personal Identification Number (PIN must be entered, the transaction has been successfully processed and the transaction has not been completed due to an error. The proposed solution increases the personal autonomy and security of blind people when paying at a merchant.

From System Expansion to System Contraction: Access to Higher Education in Poland

Science.gov (United States)

Kwiek, Marek

2013-01-01

Access to higher education in Poland is changing due to the demography of smaller cohorts of potential students. Following a demand-driven educational expansion after the collapse of communism in 1989, the higher education system is now contracting. Such expansion/contraction and growth/decline in European higher education has rarely been…

Mediatorless electron transfer in glucose dehydrogenase/laccase system adsorbed on carbon nanotubes

International Nuclear Information System (INIS)

Ratautas, D.; Marcinkevičienė, L.; Meškys, R.; Kulys, J.

2015-01-01

Highlights: • Glucose dehydrogenase from Ewingella americana (GDH) demonstrated an effective mediatorless oxidation of glucose on single-walled carbon nanotubes (SWCNT). • Laccase from Trichaptum abietinum (LAC) exhibited mediatorless oxygen reduction when the enzyme was adsorbed on SWCNT. • Simultaneous adsorption of GDH and LAC on SWCNT formed an electron transfer chain in which glucose and lactose were oxidized by oxygen in mediatorless manner. - Abstract: A mediatorless electron transfer in the chain of glucose dehydrogenase (GDH) and laccase (LAC) catalysing the oxidation of glucose by molecular oxygen was studied. To demonstrate mediatorless processes, the GDH from Ewingella americana was adsorbed on single-walled carbon nanotubes (SWCNT). The effective mediatorless oxidation of glucose proceeded at 0.2–0.4 V vs. SCE. The electrode was most active at pH 6.1, and generated 0.8 mA cm −2 biocatalytic current in the presence of 50 mM glucose. The electrode showed a bell-shaped pH dependence with pK a values of 4.1 and 7.5. LAC from Trichaptum abietinum adsorbed on SWCNT exhibited mediatorless oxygen reduction at electrode potential less than 0.65 V. The electrode was most active at pH 3.0–4.0 and generated 1.1 mA cm −2 biocatalytic current in the presence of 0.254 mM oxygen, with an apparent pK a of 1.0 and 5.4. The electrodes prepared by simultaneous adsorption of GDH and LAC on SWCNT exhibited glucose oxidation at a potential higher than 0.25 V. The oxygen consumption in the chain was demonstrated using a Clark-type oxygen electrode. The dependence of oxygen consumption on glucose and lactose concentrations as well as activity of the system on pH were measured. A model of the pH dependence as well as mediatorless consecutive glucose oxidation with oxygen catalysed by LAC/GDH system is presented. This work provides a novel approach towards the synthesis of artificial multi enzyme systems by wiring oxidoreductases with SWCNT, and offers a better

DOE's nation-wide system for access control can solve problems for the federal government

International Nuclear Information System (INIS)

Callahan, S.; Tomes, D.; Davis, G.; Johnson, D.; Strait, S.

1996-07-01

The U.S. Department of Energy's (DOE's) ongoing efforts to improve its physical and personnel security systems while reducing its costs, provide a model for federal government visitor processing. Through the careful use of standardized badges, computer databases, and networks of automated access control systems, the DOE is increasing the security associated with travel throughout the DOE complex, and at the same time, eliminating paperwork, special badging, and visitor delays. The DOE is also improving badge accountability, personnel identification assurance, and access authorization timeliness and accuracy. Like the federal government, the DOE has dozens of geographically dispersed locations run by many different contractors operating a wide range of security systems. The DOE has overcome these obstacles by providing data format standards, a complex-wide virtual network for security, the adoption of a standard high security system, and an open-systems-compatible link for any automated access control system. If the location's level of security requires it, positive visitor identification is accomplished by personal identification number (PIN) and/or by biometrics. At sites with automated access control systems, this positive identification is integrated into the portals

A mobile console for local access to accelerator control systems.

CERN Multimedia

1981-01-01

Microprocessors were installed as auxiliary crate controllers (ACCs) in the CAMAC interface of control systems for various accelerators. The same ACC was also at the hearth of a stand-alone system in the form of a mobile console. This was also used for local access to the control systems for tests and development work (Annual Report 1981, p. 80, Fig. 10).

A System to Generate SignWriting for Video Tracks Enhancing Accessibility of Deaf People

OpenAIRE

Elena Verdú; Cristina Pelayo G-Bustelo; Ángeles Martínez Sánchez; Rubén Gonzalez-Crespo

2017-01-01

Video content has increased much on the Internet during last years. In spite of the efforts of different organizations and governments to increase the accessibility of websites, most multimedia content on the Internet is not accessible. This paper describes a system that contributes to make multimedia content more accessible on the Web, by automatically translating subtitles in oral language to Sign Writing, a way of writing Sign Language. This system extends the functionality of a general we...

Privacy and Access Control for IHE-Based Systems

Science.gov (United States)

Katt, Basel; Breu, Ruth; Hafner, Micahel; Schabetsberger, Thomas; Mair, Richard; Wozak, Florian

Electronic Health Record (EHR) is the heart element of any e-health system, which aims at improving the quality and efficiency of healthcare through the use of information and communication technologies. The sensitivity of the data contained in the health record poses a great challenge to security. In this paper we propose a security architecture for EHR systems that are conform with IHE profiles. In this architecture we are tackling the problems of access control and privacy. Furthermore, a prototypical implementation of the proposed model is presented.

Bus Access Optimisation for FlexRay-based Distributed Embedded Systems

DEFF Research Database (Denmark)

Pop, Traian; Pop, Paul; Eles, Petru

2007-01-01

-real time communication in a deterministic manner. In this paper, we propose techniques for optimising the FlexRay bus access mechanism of a distributed system, so that the hard real-time deadlines are met for all the tasks and messages in the system. We have evaluated the proposed techniques using...

A novel technique to extract events from access control system and locate persons

International Nuclear Information System (INIS)

Vincent, M.; Vaidyanathan, Mythili; Patidar, Suresh Chandra; Prabhakara Rao, G.

2011-01-01

Indira Gandhi Centre for Atomic Research houses many laboratories which handle radioactive materials and classified materials. Protection and accounting of men and material and critical facilities are important aspect of nuclear security. Access Control System (ACS) is used to enhance the protective measures against elevated threat environment. Access control system hardware consists of hand geometry readers, RFID readers, Controllers, Electromagnetic door locks, Turnstiles, fiber cable laying and termination etc. Access Control System controls and monitors the people accessing the secured facilities. Access Control System generates events on: 1. Showing of RFID card, 2. Rotation of turnstile, 3. Download of valid card numbers, 4. Generation of alarms etc. Access control system turnstiles are located in main entrance of a facility, entrance of inside laboratory and door locks are fixed on secured facilities. Events are stored in SQL server database. From the events stored in database a novel technique is developed to extract events and list the persons in a particular facility, list all entry/exit events on one day, list the first in and last out entries. This paper discusses the complex multi level group by queries and software developed to extract events from database, locate persons and generate reports. Software is developed as a web application in ASP.Net and query is written in SQL. User can select the doors, type of events and generate reports. Reports are generated using the master data stored about employees RFID cards and events data stored in tables. Four types of reports are generated 1. Plant Emergency Report, 2. Locate User Report, 3. Entry - Exit Report, 4. First in Last out Report. To generate plant emergency report for whole plant only events generated in outer gates have to be considered. To generate plant emergency report for inside laboratory, events generated in entrance gates have to be ignored. (author)

First Nustar Observations of the Bl Lac-Type Blazar Pks 2155-304: Constraints on the Jet Content and Distribution of Radiating Particles

DEFF Research Database (Denmark)

Madejski, G. M.; Nalewajko, K.; Madsen, K. K.

2016-01-01

We report the first hard X-ray observations with NuSTAR of the BL Lac-type blazar PKS 2155-304, augmented with soft X-ray data from XMM-Newton and γ-ray data from the Fermi Large Area Telescope, obtained in 2013 April when the source was in a very low flux state. A joint NuSTAR and XMM spectrum, ...

Control of Lactose Transport, β-Galactosidase Activity, and Glycolysis by CcpA in Streptococcus thermophilus : Evidence for Carbon Catabolite Repression by a Non-Phosphoenolpyruvate-Dependent Phosphotransferase System Sugar

NARCIS (Netherlands)

Bogaard, Patrick T.C. van den; Kleerebezem, Michiel; Kuipers, Oscar P.; Vos, Willem M. de

2000-01-01

Streptococcus thermophilus, unlike many other gram-positive bacteria, prefers lactose over glucose as the primary carbon and energy source. Moreover, lactose is not taken up by a phosphoenolpyruvate-dependent phosphotransferase system (PTS) but by the dedicated transporter LacS. In this paper we

Advances in the graphitization protocol at the Radiocarbon Laboratory of the Universidade Federal Fluminense (LAC-UFF) in Brazil

Energy Technology Data Exchange (ETDEWEB)

Macario, Kita D., E-mail: kitamacario@gmail.com [Departamento de Física, Instituto deFísica, Universidade Federal Fluminense, Campus da Praia Vermelha, Av. Gal. Milton Tavares de Souza s/n°, Niterói, RJ, 24210-346 (Brazil); Oliveira, Fabiana M. [Departamento de Física, Instituto deFísica, Universidade Federal Fluminense, Campus da Praia Vermelha, Av. Gal. Milton Tavares de Souza s/n°, Niterói, RJ, 24210-346 (Brazil); Carvalho, Carla [Departamento de Geoquímica, Instituto de Química, Universidade Federal Fluminense, Campus do Valonguinho, Outeiro São João Batista, s/n°, Niterói, RJ, 24020-150 (Brazil); Santos, Guaciara M.; Xu, Xiaomei [Department of Earth System Science, B321 Croul Hall, University of California Irvine, Irvine, CA, 92697-3100 (United States); Chanca, Ingrid S.; Alves, Eduardo Q.; Jou, Renata M.; Oliveira, Maria Isabela; Pereira, Bruna B.; Moreira, Vinicius; Muniz, Marcelo C.; Linares, Roberto; Gomes, Paulo Roberto Silveira; Meigikos dos Anjos, Roberto [Departamento de Física, Instituto deFísica, Universidade Federal Fluminense, Campus da Praia Vermelha, Av. Gal. Milton Tavares de Souza s/n°, Niterói, RJ, 24210-346 (Brazil); and others

2015-10-15

In this paper, we summarize the sample preparation methods currently used at the Radiocarbon Laboratory of the Universidade Federal Fluminense (LAC-UFF) in Brazil. We also report on a series of results with regards to the graphitization protocol. Tests with different temperatures and baking times were performed, and carbon stable isotope ratios of graphite were measured by an EA–IRMS (elemental analyzer coupled with an isotopic ratio mass spectrometer) to infer the completeness of the graphitization reaction. We monitored the muffle furnace temperature using an independent thermocouple and found a −60 °C offset, which may have caused the lower graphitization yields (detected from the large isotopic fractionation on several reference materials targets). At a temperature of 520 °C, the isotopic fractionation in the graphitization reaction was systematically lower (−5‰ in average) and the overall scattering was reduced. As long as isotopic fractionation corrections are made using the online stable isotopes ratios provided by the AMS system, the accuracy of the {sup 14}C results should be maintained.

Design of pulse waveform for waveform division multiple access UWB wireless communication system.

Science.gov (United States)

Yin, Zhendong; Wang, Zhirui; Liu, Xiaohui; Wu, Zhilu

2014-01-01

A new multiple access scheme, Waveform Division Multiple Access (WDMA) based on the orthogonal wavelet function, is presented. After studying the correlation properties of different categories of single wavelet functions, the one with the best correlation property will be chosen as the foundation for combined waveform. In the communication system, each user is assigned to different combined orthogonal waveform. Demonstrated by simulation, combined waveform is more suitable than single wavelet function to be a communication medium in WDMA system. Due to the excellent orthogonality, the bit error rate (BER) of multiuser with combined waveforms is so close to that of single user in a synchronous system. That is to say, the multiple access interference (MAI) is almost eliminated. Furthermore, even in an asynchronous system without multiuser detection after matched filters, the result is still pretty ideal and satisfactory by using the third combination mode that will be mentioned in the study.

Embedded systems for supporting computer accessibility.

Science.gov (United States)

Mulfari, Davide; Celesti, Antonio; Fazio, Maria; Villari, Massimo; Puliafito, Antonio

2015-01-01

Nowadays, customized AT software solutions allow their users to interact with various kinds of computer systems. Such tools are generally available on personal devices (e.g., smartphones, laptops and so on) commonly used by a person with a disability. In this paper, we investigate a way of using the aforementioned AT equipments in order to access many different devices without assistive preferences. The solution takes advantage of open source hardware and its core component consists of an affordable Linux embedded system: it grabs data coming from the assistive software, which runs on the user's personal device, then, after processing, it generates native keyboard and mouse HID commands for the target computing device controlled by the end user. This process supports any operating system available on the target machine and it requires no specialized software installation; therefore the user with a disability can rely on a single assistive tool to control a wide range of computing platforms, including conventional computers and many kinds of mobile devices, which receive input commands through the USB HID protocol.

Typha control efficiency of a weed-cutting boat in the Lac de Guiers in Senegal : A preliminary study on mowing speed and re-growth capacity

NARCIS (Netherlands)

Hellsten, S.; Dieme, C.; Mbengue, M.; Janauer, G.A.; Hollander, den N.G.; Pieterse, A.H.

1999-01-01

Prolific growth of Typha australis in the lower part of the Senegal River and the Lac de Guiers resulted from changed ecological conditions following the construction of two high dams in the Senegal River. Fluctuation of the water level has decreased markedly and the water has changed from brackish

A Comprehensive System for Monitoring Urban Accessibility in Smart Cities.

Science.gov (United States)

Mora, Higinio; Gilart-Iglesias, Virgilio; Pérez-Del Hoyo, Raquel; Andújar-Montoya, María Dolores

2017-08-09

The present work discusses the possibilities offered by the evolution of Information and Communication Technologies with the aim of designing a system to dynamically obtain knowledge of accessibility issues in urban environments. This system is facilitated by technology to analyse the urban user experience and movement accessibility, which enabling accurate identification of urban barriers and monitoring its effectiveness over time. Therefore, the main purpose of the system is to meet the real needs and requirements of people with movement disabilities. The information obtained can be provided as a support service for decision-making to be used by city government, institutions, researchers, professionals and other individuals of society in general to improve the liveability and quality of the lives of citizens. The proposed system is a means of social awareness that makes the most vulnerable groups of citizens visible by involving them as active participants. To perform and implement the system, the latest communication and positioning technologies for smart sensing have been used, as well as the cloud computing paradigm. Finally, to validate the proposal, a case study has been presented using the university environment as a pre-deployment step in urban environments.

Open-Access, Low-Magnetic-Field MRI System for Lung Research

Science.gov (United States)

Mair, Ross W.; Rosen, Matthew S.; Tsai, Leo L.; Walsworth, Ronald L.; Hrovat, Mirko I.; Patz, Samuel; Ruset, Iullian C.; Hersman, F. William

2009-01-01

An open-access magnetic resonance imaging (MRI) system is being developed for use in research on orientational/gravitational effects on lung physiology and function. The open-access geometry enables study of human subjects in diverse orientations. This system operates at a magnetic flux density, considerably smaller than the flux densities of typical other MRI systems, that can be generated by resistive electromagnet coils (instead of the more-expensive superconducting coils of the other systems). The human subject inhales air containing He-3 or Xe-129 atoms, the nuclear spins of which have been polarized by use of a laser beam to obtain a magnetic resonance that enables high-resolution gas space imaging at the low applied magnetic field. The system includes a bi-planar, constant-current, four-coil electromagnet assembly and associated electronic circuitry to apply a static magnetic field of 6.5 mT throughout the lung volume; planar coils and associated circuitry to apply a pulsed magnetic-field-gradient for each spatial dimension; a single, detachable radio-frequency coil and associated circuitry for inducing and detecting MRI signals; a table for supporting a horizontal subject; and electromagnetic shielding surrounding the electromagnet coils.

Development of a defined-sequence DNA system for use in DNA misrepair studies

International Nuclear Information System (INIS)

Sutton, S.; Tobias, C.A.

1984-01-01

The authors have developed a system that allows them to study cellular DNA repair processes at the molecular level. In particular, the authors are using this system to examine the consequences of a misrepair of radiation-induced DNA damage, as a function of dose. The cells being used are specially engineered haploid yeast cells. Maintained in the cells, at one copy per cell, is a cen plasmid, a plasmid that behaves like a functional chromosome. This plasmid carries a small defined sequence of DNA from the E. coli lac z gene. It is this lac z region (called the alpha region) that serves as the target for radiation damage. Two copies of the complimentary portion of the lac z gene are integrated into the yeast genome. Irradiated cells are screened for possible mutation in the alpha region by testing the cells' ability to hydrolyze xgal, a lactose substrate. The DNA of interest is then extracted from the cells, sequenced, and the sequence is compared to that of the control. Unlike the usual defined-sequence DNA systems, theirs is an in vivo system. A disadvantage is the relatively high background mutation rate. Results achieved with this system, as well as future applications, are discussed

Does the public deserve free access to climate system science?

Science.gov (United States)

Grigorov, Ivo

2010-05-01

Some time ago it was the lack of public access to medical research data that really stirred the issue and gave inertia for legislation and a new publishing model that puts tax payer-funded medical research in the hands of those who fund it. In today's age global climate change has become the biggest socio-economic challenge, and the same argument resonates: climate affects us all and the publicly-funded science quantifying it should be freely accessible to all stakeholders beyond academic research. Over the last few years the ‘Open Access' movement to remove as much as possible subscription, and other on-campus barriers to academic research has rapidly gathered pace, but despite significant progress, the climate system sciences are not among the leaders in providing full access to their publications and data. Beyond the ethical argument, there are proven and tangible benefits for the next generation of climate researchers to adapt the way their output is published. Through the means provided by ‘open access', both data and ideas can gain more visibility, use and citations for the authors, but also result in a more rapid exchange of knowledge and ideas, and ultimately progress towards a sought solution. The presentation will aim to stimulate discussion and seek progress on the following questions: Should free access to climate research (& data) be mandatory? What are the career benefits of using ‘open access' for young scientists? What means and methods should, or could, be incorporated into current European graduate training programmes in climate research, and possible ways forward?

78 FR 43963 - Twenty-Third Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

Science.gov (United States)

2013-07-22

... Committee 224, Airport Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security... meeting of the RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting...

A Rewritable, Random-Access DNA-Based Storage System.

Science.gov (United States)

Yazdi, S M Hossein Tabatabaei; Yuan, Yongbo; Ma, Jian; Zhao, Huimin; Milenkovic, Olgica

2015-09-18

We describe the first DNA-based storage architecture that enables random access to data blocks and rewriting of information stored at arbitrary locations within the blocks. The newly developed architecture overcomes drawbacks of existing read-only methods that require decoding the whole file in order to read one data fragment. Our system is based on new constrained coding techniques and accompanying DNA editing methods that ensure data reliability, specificity and sensitivity of access, and at the same time provide exceptionally high data storage capacity. As a proof of concept, we encoded parts of the Wikipedia pages of six universities in the USA, and selected and edited parts of the text written in DNA corresponding to three of these schools. The results suggest that DNA is a versatile media suitable for both ultrahigh density archival and rewritable storage applications.

The assessment of exploitation process of power for access control system

Science.gov (United States)

Wiśnios, Michał; Paś, Jacek

2017-10-01

The safety of public utility facilities is a function not only of effectiveness of the electronic safety systems, used for protection of property and persons, but it also depends on the proper functioning of their power supply systems. The authors of the research paper analysed the power supply systems, which are used in buildings for the access control system that is integrated with the closed-circuit TV. The Access Control System is a set of electronic, electromechanical and electrical devices and the computer software controlling the operation of the above-mentioned elements, which is aimed at identification of people, vehicles allowed to cross the boundary of the reserved area, to prevent from crossing the reserved area and to generate the alarm signal informing about the attempt of crossing by an unauthorised entity. The industrial electricity with appropriate technical parameters is a basis of proper functioning of safety systems. Only the electricity supply to the systems is not equivalent to the operation continuity provision. In practice, redundant power supply systems are used. In the carried out reliability analysis of the power supply system, various power circuits of the system were taken into account. The reliability and operation requirements for this type of system were also included.

Burn care in Los Angeles, California: LAC+USC experience 1994-2004.

Science.gov (United States)

Garner, Warren L; Reiss, Matthew

2005-01-01

The LAC+USC Burn Center has admitted 3118 patients for treatment in the last 10 years. A majority of patients were young adults (1868), with the second largest group being small children (543). The ethnicity of the patients reflects the diverse nature of the population of Los Angeles County. Forty-eight percent of injuries were less than 5% TBSA and approximately 2% were greater than 60% TBSA. Eighty-two percent were accidental injuries. Sixty percent of admitted patients underwent skin grafting. Mortality was negligible in the group with burns over less than 10% of their body and very high (15/19), 79% in the most severely burned group. Further, there was a high correlation between age and mortality. Complications during treatment included: deep venous thrombosis 1% per year; pulmonary emboli in 5 patients; endotracheal tube dislodgment early or self-extubation about 1 month (11.3 per year); 4.5 patients per year who developed acute renal failure; abdominal compartment syndrome developed in 4.7 patients each year; heterotopic ossification was seen in 4 patients (0.4%); 4 patients (0.4%) developed stage II-IV pressure sores; hypothermia was present in 0.8% of patients.

Gene fusions with lacZ by duplication insertion in the radioresistant bacterium Deinococcus radiodurans

International Nuclear Information System (INIS)

Lennon, E.; Minton, K.W.

1990-01-01

Deinococcus radiodurans is the most-studied species of a eubacterial family characterized by extreme resistance to DNA damage. We have focused on developing molecular biological techniques to investigate the genetics of this organism. We report construction of lacZ gene fusions by a method involving both in vitro splicing and the natural transformation of D. radiodurans. Numerous fusion strains were identified by expression of beta-galactosidase. Among these fusion strains, several were inducible by exposure to the DNA-damaging agent mitomycin C, and four of the inducible fusion constructs were cloned in Escherichia coli. Hybridization studies indicate that one of the damage-inducible genes contains a sequence reiterated throughout the D. radiodurans chromosome. Survival measurements show that two of the fusion strains have increased sensitivity to mitomycin C, suggesting that the fusions within these strains inactivate repair functions

Seed quality of common bean accessions under organic and conventional farming systems

Directory of Open Access Journals (Sweden)

Diego Medeiros Gindri

2017-06-01

Full Text Available Agrobiodiversity is essential for a sustainable food production, and the knowledge of the potential characteristics of landrace seeds may prompt farmers to adopt the habit of seed conservation for this species. This study aimed at categorizing landrace and commercial common bean (Phaseolus vulgaris L. accessions, according to the physiological quality (viability and vigor of seeds produced in the field, during two growing seasons, under organic and conventional farming systems. Germination percentage, field emergence, electrical conductivity, accelerated aging, cold test and seedling length were assessed. The landrace bean accessions exhibit diversity in the physiological seed quality, in terms of their viability and vigor. No differences were observed between the farming systems, in relation to the physiological quality of the seeds produced. The categorization of landrace common bean accessions allows to identify those with superior physiological seed quality.

Evaluasi Pemanfaatan Wireless Internet Protocol Access System di Kota Malang

Directory of Open Access Journals (Sweden)

Ahmad Budi Setiawan

2012-03-01

Full Text Available WIPAS (Wireless Internet Protocol Accsess System adalah salah satu teknologi pita lebar (broadband yang terbaru. Teknologi tersebut dikembangkan berdasarkan model point-to-multipoint access system pada jaringan nirkabel tetap atau Fixed Wireless Access (FWA dengan memanfaatkan pita frekuensi 26-GHz. Dengan besarnya pita frekuensi yang digunakan, teknologi WIPAS dapat menampung kapasitas akses untuk lalu lintas jaringan yang sangat besar. Dalam penelitian ini akan dikaji dan dievaluasi efektifitas penggunaan teknologi WIPAS melalui kasus pemanfaatan teknologi WIPAS untuk pemberdayaan komunitas di kota Malang. Dalam penelitian ini juga akan dideskripsikan pemanfaatan teknologi WIPAS untuk melihat manfaat penggunaan teknologi tersebut. Penelitian ini dilakukan dengan metode kualitatif dengan melakukan evaluasi terhadap infrastruktur yang telah dibangun untuk melihat efektifitas pemanfaatan WIPAS. Hasil penelitian ini adalah sebuah kajian evaluatif tentang pemanfaatan WIPAS di kota Malang dan rekomendasi untuk implementasi lebih lanjut.

An end-to-end secure patient information access card system.

Science.gov (United States)

Alkhateeb, A; Singer, H; Yakami, M; Takahashi, T

2000-03-01

The rapid development of the Internet and the increasing interest in Internet-based solutions has promoted the idea of creating Internet-based health information applications. This will force a change in the role of IC cards in healthcare card systems from a data carrier to an access key medium. At the Medical Informatics Department of Kyoto University Hospital we are developing a smart card patient information project where patient databases are accessed via the Internet. Strong end-to-end data encryption is performed via Secure Socket Layers, transparent to transmit patient information. The smart card is playing the crucial role of access key to the database: user authentication is performed internally without ever revealing the actual key. For easy acceptance by healthcare professionals, the user interface is integrated as a plug-in for two familiar Web browsers, Netscape Navigator and MS Internet Explorer.

Presidential Management Fellows (PMF) Talent Acquisition System, PMF-TAS (ACCESS CONTROLLED)

Data.gov (United States)

Office of Personnel Management — Application and Assessment system for Presidential Management Fellows (PMF) and PMF Science, Technology, Engineering, and Math (STEM) programs. This sytem is access...

28 CFR 16.72 - Exemption of Office of the Associate Attorney General System-limited access.

Science.gov (United States)

2010-07-01

... Attorney General System-limited access. 16.72 Section 16.72 Judicial Administration DEPARTMENT OF JUSTICE....72 Exemption of Office of the Associate Attorney General System—limited access. (a) The following...) General Files System of the Office of the Associate Attorney General (JUSTICE/AAG-001). These exemptions...

TECHNOLOGY FOR ADMINISTERING OF THE ACCESS TO INFORMATION RESOURCES IN MANAGEMENT SYSTEM ON THE AVIATION ENTERPRISE

Directory of Open Access Journals (Sweden)

Andrey V. Degtyarev

2015-01-01

Full Text Available The task of administering software-information complex occurs duringthe development of application systems for managing business-processes and is connected with the organization of access forusers to information resources in conditions of multi-user information systems for management. For solution of this problem proposed theapproach, which is based on a hierarchical system of access rightsto information resources on the levels: tool, object and procedural.Keywords: software-information complex, information resources,administering, permissions, separation of powers, access model.

ENDOR determination of the proton positions around Gd3+ in La(C2H5SO4)3.9H2O

International Nuclear Information System (INIS)

Beer, R. de; Biesboer, F.; Ormondt, D. van

1976-01-01

The water proton positions around Gd 3+ in La(C 2 H 5 SO 4 ) 3 .9H 2 O have been determined by means of ENDOR. The positions of the nearest neighbour water oxygens are discussed on the basis of a superposition model analysis of the ratios b 2 0 /A 2 0 2 >, b 6 6 /b 6 0 and mod(A 6 6 )modA 6 0 . (Auth.)

TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts.

Science.gov (United States)

Kucab, Jill E; Zwart, Edwin P; van Steeg, Harry; Luijten, Mirjam; Schmeiser, Heinz H; Phillips, David H; Arlt, Volker M

2016-03-01

3-Nitrobenzanthrone (3-NBA) is a highly mutagenic compound and possible human carcinogen found in diesel exhaust. 3-NBA forms bulky DNA adducts following metabolic activation and induces predominantly G:CT:A transversions in a variety of experimental systems. Here we investigated the influence of nucleotide excision repair (NER) on 3-NBA-induced mutagenesis of the human tumour suppressor gene TP53 and the reporter gene lacZ. To this end we utilised Xpa -knockout (Xpa-Null) human TP53 knock-in (Hupki) embryo fibroblasts (HUFs). As Xpa is essential for NER of bulky DNA adducts, we hypothesized that DNA adducts induced by 3-NBA would persist in the genomes of Xpa-Null cells and lead to an increased frequency of mutation. The HUF immortalisation assay was used to select for cells harbouring TP53 mutations following mutagen exposure. We found that Xpa-Null Hupki mice and HUFs were more sensitive to 3-NBA treatment than their wild-type (Xpa-WT) counterparts. However, following 3-NBA treatment and immortalisation, a similar frequency of TP53-mutant clones arose from Xpa-WT and Xpa-Null HUF cultures. In cells from both Xpa genotypes G:CT:A transversion was the predominant TP53 mutation type and mutations exhibited bias towards the non-transcribed strand. Thirty-two percent of 3-NBA-induced TP53 mutations occurred at CpG sites, all of which are hotspots for mutation in smokers' lung cancer (codons 157, 158, 175, 245, 248, 273, 282). We also examined 3-NBA-induced mutagenesis of an integrated lacZ reporter gene in HUFs, where we again observed a similar mutant frequency in Xpa-WT and Xpa-Null cells. Our findings suggest that 3-NBA-DNA adducts may evade removal by global genomic NER; the persistence of 3-NBA adducts in DNA may be an important factor in its mutagenicity. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

2008 Stability, Security, Transition and Reconstruction Operations Conference

Science.gov (United States)

2008-09-04

Facilitator Power of Public-Private Partnerships • Health Professional Education • Greater Access to Care China Diabetes Education Program Dominican Republic...Argentina Canada Chile Colombia Ecuador Peru Uruguay Interagency, multinational, inter-institutional partnerships State Department Homeland Security...Disaster Preparedness Disaster Response Regional Response Capacity OFDA-LAC / MDROs Regional Security System (RSS) UNCLASSIFIED ECUADOR / KY PERU / WV

Access to Justice in the European Convention on Human Rights System

NARCIS (Netherlands)

Glas, L.R.; Gerards, J.H.

2017-01-01

The numerous reforms to the Convention system of the past two decades have unquestionably had an effect on applicants’ means to access justice in the system. It is, however, open to question how these changes should be evaluated: with reference to the individual right to petition, or with reference

Propagation Characteristics in an Underground Shopping Area for 5GHz-band Wireless Access Systems

Science.gov (United States)

Itokawa, Kiyohiko; Kita, Naoki; Sato, Akio; Matsue, Hideaki; Mori, Daisuke; Watanabe, Hironobu

5-GHz band wireless access systems, such as the RLAN (Radio Local Area Network) system of IEEE802.11a, HiperLAN/2, HiSWANa and AWA, are developed and provide transmission rates over 20 Mbps for indoor use. Those 5-GHz access systems are expected to extend service areas from the office to the so-called “hot-spot" in public areas. Underground shopping malls are one of the anticipated service areas for such a nomadic wireless access service. Broadband propagation characteristics are required for radio zone design in an underground mall environment despite previous results obtained by narrow band measurements. This paper presents results of an experimental study on the propagation characteristics for broadband wireless access systems in an underground mall environment. First, broadband propagation path loss is measured and formulated considering human body shadowing. A ray trace simulation is used to clarify the basic propagation mechanism in such a closed environment. Next, a distance dependency of the delay spread during a crowded time period, rush hour, is found to be at most 65 nsec, which is under the permitted maximum value of the present 5-GHz systems. Finally, above propagation characteristics support the result of transmission test carried out by using AWA equipment.

On board processing for future satellite communications systems: Comparison of FDM, TDM and hybrid accessing schemes

Science.gov (United States)

Berk, G.; Jean, P. N.; Rotholz, E.

1982-01-01

Several satellite uplink and downlink accessing schemes for customer premises service are compared. Four conceptual system designs are presented: satellite-routed frequency division multiple access (FDMA), satellite-switched time division multiple access (TDMA), processor-routed TDMA, and frequency-routed TDMA, operating in the 30/20 GHz band. The designs are compared on the basis of estimated satellite weight, system capacity, power consumption, and cost. The systems are analyzed for fixed multibeam coverage of the continental United States. Analysis shows that the system capacity is limited by the available satellite resources and by the terminal size and cost.

Information system architecture to support transparent access to distributed, heterogeneous data sources

International Nuclear Information System (INIS)

Brown, J.C.

1994-08-01

Quality situation assessment and decision making require access to multiple sources of data and information. Insufficient accessibility to data exists for many large corporations and Government agencies. By utilizing current advances in computer technology, today's situation analyst's have a wealth of information at their disposal. There are many potential solutions to the information accessibility problem using today's technology. The United States Department of Energy (US-DOE) faced this problem when dealing with one class of problem in the US. The result of their efforts has been the creation of the Tank Waste Information Network System -- TWINS. The TWINS solution combines many technologies to address problems in several areas such as User Interfaces, Transparent Access to Multiple Data Sources, and Integrated Data Access. Data related to the complex is currently distributed throughout several US-DOE installations. Over time, each installation has adopted their own set of standards as related to information management. Heterogeneous hardware and software platforms exist both across the complex and within a single installation. Standards for information management vary between US-DOE mission areas within installations. These factors contribute to the complexity of accessing information in a manner that enhances the performance and decision making process of the analysts. This paper presents one approach taken by the DOE to resolve the problem of distributed, heterogeneous, multi-media information management for the HLW Tank complex. The information system architecture developed for the DOE by the TWINS effort is one that is adaptable to other problem domains and uses

GP preferences for information systems: conjoint analysis of speed, reliability, access and users.

Science.gov (United States)

Wyatt, Jeremy C; Batley, Richard P; Keen, Justin

2010-10-01

To elicit the preferences and trade-offs of UK general practitioners about key features of health information systems, to help inform the design of such systems in future. A stated choice study to uncover implicit preferences based on a binary choice between scenarios presented in random order. were all 303 general practice members of the UK Internet service provider, Medix who were approached by email to participate. The main outcome measure was the number of seconds delay in system response that general practitioners were willing to trade off for each key system feature: the reliability of the system, the sites from which the system could be accessed and which staff are able to view patient data. Doctors valued speed of response most in information systems but would be prepared to wait 28 seconds to access a system in exchange for improved reliability from 95% to 99%, a further 2 seconds for an improvement to 99.9% and 27 seconds for access to data from anywhere including their own home compared with one place in a single health care premises. However, they would require a system that was 14 seconds faster to compensate for allowing social care as well as National Health Service staff to read patient data. These results provide important new evidence about which system characteristics doctors value highly, and hence which characteristics designers need to focus on when large scale health information systems are planned. © 2010 Blackwell Publishing Ltd.

WHAT IS THE REDSHIFT OF THE GAMMA-RAY BL LAC SOURCE S4 0954+65?

Energy Technology Data Exchange (ETDEWEB)

Landoni, M. [INAF—Istituto Nazionale di Astrofisica, Osservatorio Astronomico di Brera, Via E. Bianchi 46, I-23807 Merate (Italy); Falomo, R. [INAF—Istituto Nazionale di Astrofisica, Osservatorio Astronomico di Padova, Vicolo dell’Osservatorio 5, I-35122 Padova (Italy); Treves, A. [Universita’ degli Studi dell’Insubria, Via Valleggio 11, I-22100 (Italy); Scarpa, R.; Payá, D. Reverte, E-mail: marco.landoni@brera.inaf.it [Instituto de Astrofsica de Canarias, C/O Via Lactea, s/n E38205—La Laguna (Tenerife) (Spain)

2015-12-15

High signal-to-noise ratio spectroscopic observations of the BL Lac object S4 0954+65 at the alleged redshift z = 0.367 are presented. This source was detected at gamma frequencies by the MAGIC (TeV) and FERMI (GeV) telescopes during a remarkable outburst that occurred in 2015 February, making the determination of its distance particularly relevant for our understanding of the properties of the extragalactic background light. Contrary to previous reports on the redshift, we found that the optical spectrum is featureless at an equivalent width limit of ∼0.1 Å. A critical analysis of the existing observations indicates that the redshift is still unknown. Based on the new data we estimate a lower limit to the redshift at z ≥ 0.45.

28 CFR 16.83 - Exemption of the Executive Office for Immigration Review System-limited access.

Science.gov (United States)

2010-07-01

... Immigration Review System-limited access. 16.83 Section 16.83 Judicial Administration DEPARTMENT OF JUSTICE....83 Exemption of the Executive Office for Immigration Review System—limited access. (a) The following system of records is exempt from 5 U.S.C. 552a(d): (1) The Executive Office for Immigration Review's...

Multiple Access Interference Reduction Using Received Response Code Sequence for DS-CDMA UWB System

Science.gov (United States)

Toh, Keat Beng; Tachikawa, Shin'ichi

This paper proposes a combination of novel Received Response (RR) sequence at the transmitter and a Matched Filter-RAKE (MF-RAKE) combining scheme receiver system for the Direct Sequence-Code Division Multiple Access Ultra Wideband (DS-CDMA UWB) multipath channel model. This paper also demonstrates the effectiveness of the RR sequence in Multiple Access Interference (MAI) reduction for the DS-CDMA UWB system. It suggests that by using conventional binary code sequence such as the M sequence or the Gold sequence, there is a possibility of generating extra MAI in the UWB system. Therefore, it is quite difficult to collect the energy efficiently although the RAKE reception method is applied at the receiver. The main purpose of the proposed system is to overcome the performance degradation for UWB transmission due to the occurrence of MAI during multiple accessing in the DS-CDMA UWB system. The proposed system improves the system performance by improving the RAKE reception performance using the RR sequence which can reduce the MAI effect significantly. Simulation results verify that significant improvement can be obtained by the proposed system in the UWB multipath channel models.

Digital Autonomous Terminal Access Communication (DATAC) system

Science.gov (United States)

Novacki, Stanley M., III

1987-01-01

In order to accommodate the increasing number of computerized subsystems aboard today's more fuel efficient aircraft, the Boeing Co. has developed the DATAC (Digital Autonomous Terminal Access Control) bus to minimize the need for point-to-point wiring to interconnect these various systems, thereby reducing total aircraft weight and maintaining an economical flight configuration. The DATAC bus is essentially a local area network providing interconnections for any of the flight management and control systems aboard the aircraft. The task of developing a Bus Monitor Unit was broken down into four subtasks: (1) providing a hardware interface between the DATAC bus and the Z8000-based microcomputer system to be used as the bus monitor; (2) establishing a communication link between the Z8000 system and a CP/M-based computer system; (3) generation of data reduction and display software to output data to the console device; and (4) development of a DATAC Terminal Simulator to facilitate testing of the hardware and software which transfer data between the DATAC's bus and the operator's console in a near real time environment. These tasks are briefly discussed.

ACCESS Sub-system Performance

Science.gov (United States)

Kaiser, Mary Elizabeth; Morris, Matthew J.; Aldoroty, Lauren Nicole; Godon, David; Pelton, Russell; McCandliss, Stephan R.; Kurucz, Robert L.; Kruk, Jeffrey W.; Rauscher, Bernard J.; Kimble, Randy A.; Wright, Edward L.; Benford, Dominic J.; Gardner, Jonathan P.; Feldman, Paul D.; Moos, H. Warren; Riess, Adam G.; Bohlin, Ralph; Deustua, Susana E.; Dixon, William Van Dyke; Sahnow, David J.; Lampton, Michael; Perlmutter, Saul

2016-01-01

ACCESS: Absolute Color Calibration Experiment for Standard Stars is a series of rocket-borne sub-orbital missions and ground-based experiments designed to leverage significant technological advances in detectors, instruments, and the precision of the fundamental laboratory standards used to calibrate these instruments to enable improvements in the precision of the astrophysical flux scale through the transfer of laboratory absolute detector standards from the National Institute of Standards and Technology (NIST) to a network of stellar standards with a calibration accuracy of 1% and a spectral resolving power of 500 across the 0.35 to 1.7 micron bandpass.A cross wavelength calibration of the astrophysical flux scale to this level of precision over this broad a bandpass is relevant for the data used to probe fundamental astrophysical problems such as the SNeIa photometry based measurements used to constrain dark energy theories.We will describe the strategy for achieving this level of precision, the payload and calibration configuration, present sub-system test data, and the status and preliminary performance of the integration and test of the spectrograph and telescope. NASA APRA sounding rocket grant NNX14AH48G supports this work.

Design mobile satellite system architecture as an integral part of the cellular access digital network

Science.gov (United States)

Chien, E. S. K.; Marinho, J. A.; Russell, J. E., Sr.

1988-01-01

The Cellular Access Digital Network (CADN) is the access vehicle through which cellular technology is brought into the mainstream of the evolving integrated telecommunications network. Beyond the integrated end-to-end digital access and per call network services provisioning of the Integrated Services Digital Network (ISDN), the CADN engenders the added capability of mobility freedom via wireless access. One key element of the CADN network architecture is the standard user to network interface that is independent of RF transmission technology. Since the Mobile Satellite System (MSS) is envisioned to not only complement but also enhance the capabilities of the terrestrial cellular telecommunications network, compatibility and interoperability between terrestrial cellular and mobile satellite systems are vitally important to provide an integrated moving telecommunications network of the future. From a network standpoint, there exist very strong commonalities between the terrestrial cellular system and the mobile satellite system. Therefore, the MSS architecture should be designed as an integral part of the CADN. This paper describes the concept of the CADN, the functional architecture of the MSS, and the user-network interface signaling protocols.

Impact of optical hard limiter on the performance of an optical overlapped-code division multiple access system

Science.gov (United States)

Inaty, Elie; Raad, Robert; Tablieh, Nicole

2011-08-01

Throughout this paper, a closed form expression of the multiple access interference (MAI) limited bit error rate (BER) is provided for the multiwavelength optical code-division multiple-access system when the system is working above the nominal transmission rate limit imposed by the passive encoding-decoding operation. This system is known in literature as the optical overlapped code division multiple access (OV-CDMA) system. A unified analytical framework is presented emphasizing the impact of optical hard limiter (OHL) on the BER performance of such a system. Results show that the performance of the OV-CDMA system may be highly improved when using OHL preprocessing at the receiver side.

Broadband and scalable mobile satellite communication system for future access networks

Science.gov (United States)

Ohata, Kohei; Kobayashi, Kiyoshi; Nakahira, Katsuya; Ueba, Masazumi

2005-07-01

Due to the recent market trends, NTT has begun research into next generation satellite communication systems, such as broadband and scalable mobile communication systems. One service application objective is to provide broadband Internet access for transportation systems, temporal broadband access networks and telemetries to remote areas. While these are niche markets the total amount of capacity should be significant. We set a 1-Gb/s total transmission capacity as our goal. Our key concern is the system cost, which means that the system should be unified system with diversified services and not tailored for each application. As satellites account for a large portion of the total system cost, we set the target satellite size as a small, one-ton class dry mass with a 2-kW class payload power. In addition to the payload power and weight, the mobile satellite's frequency band is extremely limited. Therefore, we need to develop innovative technologies that will reduce the weight and maximize spectrum and power efficiency. Another challenge is the need for the system to handle up to 50 dB and a wide data rate range of other applications. This paper describes the key communication system technologies; the frequency reuse strategy, multiplexing scheme, resource allocation scheme, and QoS management algorithm to ensure excellent spectrum efficiency and support a variety of services and quality requirements in the mobile environment.

Peripheral Insertion of a Central Venous Access Device Under Fluoroscopic Guidance Using a Peripherally Accessed System (PAS) Port in the Forearm

International Nuclear Information System (INIS)

Hata, Yasuhiro; Morita, Sojiro; Morita, Yoshitaka; Awatani, Toshihide; Takasaki, Motohiro; Horimi, Tadashi; Ozawa, Zen

1998-01-01

Purpose: We describe the technique, efficacy, and complications of fluoroscopy-guided implantation of a central venous access device using a peripherally accessed system (PAS) port via the forearm. Methods: Beginning in July 1994, 105 central venous access devices were implanted in 104 patients for the long-term infusion of antibiotics or antineoplasmic agents, blood products, or parenteral nutrition. The devices was inserted under fluoroscopic guidance with real-time venography from a peripheral route. Results: All ports were successfully implanted. There were no procedure-related complications. No thrombosis or local infection was observed; however, in six patients catheter-related phlebitis occurred. Conclusion: Fluoroscopy-guided implantation of a central venous access device using a PAS port via the forearm is safe and efficacious, and injection of contrast medium through a peripheral IV catheter before introduction of the catheter helps to avoid catheter-related phlebitis

Code division multiple-access techniques in optical fiber networks. II - Systems performance analysis

Science.gov (United States)

Salehi, Jawad A.; Brackett, Charles A.

1989-08-01

A technique based on optical orthogonal codes was presented by Salehi (1989) to establish a fiber-optic code-division multiple-access (FO-CDMA) communications system. The results are used to derive the bit error rate of the proposed FO-CDMA system as a function of data rate, code length, code weight, number of users, and receiver threshold. The performance characteristics for a variety of system parameters are discussed. A means of reducing the effective multiple-access interference signal by placing an optical hard-limiter at the front end of the desired optical correlator is presented. Performance calculations are shown for the FO-CDMA with an ideal optical hard-limiter, and it is shown that using a optical hard-limiter would, in general, improve system performance.

Generation-based memory synchronization in a multiprocessor system with weakly consistent memory accesses

Energy Technology Data Exchange (ETDEWEB)

Ohmacht, Martin

2017-08-15

In a multiprocessor system, a central memory synchronization module coordinates memory synchronization requests responsive to memory access requests in flight, a generation counter, and a reclaim pointer. The central module communicates via point-to-point communication. The module includes a global OR reduce tree for each memory access requesting device, for detecting memory access requests in flight. An interface unit is implemented associated with each processor requesting synchronization. The interface unit includes multiple generation completion detectors. The generation count and reclaim pointer do not pass one another.

Generation-based memory synchronization in a multiprocessor system with weakly consistent memory accesses

Science.gov (United States)

Ohmacht, Martin

2014-09-09

In a multiprocessor system, a central memory synchronization module coordinates memory synchronization requests responsive to memory access requests in flight, a generation counter, and a reclaim pointer. The central module communicates via point-to-point communication. The module includes a global OR reduce tree for each memory access requesting device, for detecting memory access requests in flight. An interface unit is implemented associated with each processor requesting synchronization. The interface unit includes multiple generation completion detectors. The generation count and reclaim pointer do not pass one another.

Access Denied! Contrasting Data Access in the United States and Ireland

Directory of Open Access Journals (Sweden)

Grogan Samuel

2016-07-01

Full Text Available The ability of an Internet user to access data collected about himself as a result of his online activity is a key privacy safeguard. Online, data access has been overshadowed by other protections such as notice and choice. This paper describes attitudes about data access. 873 US and Irish Internet users participated in a survey designed to examine views on data access to information held by online companies and data brokers. We observed low levels of awareness of access mechanisms along with a high desire for access in both participant groups. We tested three proposed access systems in keeping with industry programs and regulatory proposals. User response was positive. We conclude that access remains an important privacy protection that is inadequately manifested in practice. Our study provides insight for lawmakers and policymakers, as well as computer scientists who implement these systems.

A Novel Medium Access Control for Ad hoc Networks Based on OFDM System

Institute of Scientific and Technical Information of China (English)

YU Yi-fan; YIN Chang-chuan; YUE Guang-xin

2005-01-01

Recently, hosts of Medium Access Control (MAC) protocols for Ad hoc radio networks have been proposed to solve the hidden terminal problem and exposed terminal problem. However most of them take into no account the interactions between physical (PHY) system and MAC protocol. Therefore, the current MAC protocols are either inefficient in the networks with mobile nodes and fading channel or difficult in hardware implementation. In this paper, we present a novel media access control for Ad hoc networks that integrates a media access control protocol termed as Dual Busy Tone Multiple Access (DBTMA) into Orthogonal Frequency Division Multiplexing (OFDM) system proposed in IEEE 802.11a standard. The analysis presented in the paper indicates that the proposed MAC scheme achieves performance improvement over IEEE 802.11 protocol about 25%～80% especially in the environment with high mobility and deep fading. The complexity of the proposed scheme is also lower than other implementation of similar busy tone solution. Furthermore, it is compatible with IEEE 802.11a networks.

Health Information System Role-Based Access Control Current Security Trends and Challenges.

Science.gov (United States)

de Carvalho Junior, Marcelo Antonio; Bandiera-Paiva, Paulo

2018-01-01

This article objective is to highlight implementation characteristics, concerns, or limitations over role-based access control (RBAC) use on health information system (HIS) using industry-focused literature review of current publishing for that purpose. Based on the findings, assessment for indication of RBAC is obsolete considering HIS authorization control needs. We have selected articles related to our investigation theme "RBAC trends and limitations" in 4 different sources related to health informatics or to the engineering technical field. To do so, we have applied the following search query string: "Role-Based Access Control" OR "RBAC" AND "Health information System" OR "EHR" AND "Trends" OR "Challenges" OR "Security" OR "Authorization" OR "Attacks" OR "Permission Assignment" OR "Permission Relation" OR "Permission Mapping" OR "Constraint". We followed PRISMA applicable flow and general methodology used on software engineering for systematic review. 20 articles were selected after applying inclusion and exclusion criteria resulting contributions from 10 different countries. 17 articles advocate RBAC adaptations. The main security trends and limitations mapped were related to emergency access, grant delegation, and interdomain access control. Several publishing proposed RBAC adaptations and enhancements in order to cope current HIS use characteristics. Most of the existent RBAC studies are not related to health informatics industry though. There is no clear indication of RBAC obsolescence for HIS use.

Surface radiant flux densities inferred from LAC and GAC AVHRR data

Science.gov (United States)

Berger, F.; Klaes, D.

To infer surface radiant flux densities from current (NOAA-AVHRR, ERS-1/2 ATSR) and future meteorological (Envisat AATSR, MSG, METOP) satellite data, the complex, modular analysis scheme SESAT (Strahlungs- und Energieflüsse aus Satellitendaten) could be developed (Berger, 2001). This scheme allows the determination of cloud types, optical and microphysical cloud properties as well as surface and TOA radiant flux densities. After testing of SESAT in Central Europe and the Baltic Sea catchment (more than 400scenes U including a detailed validation with various surface measurements) it could be applied to a large number of NOAA-16 AVHRR overpasses covering the globe.For the analysis, two different spatial resolutions U local area coverage (LAC) andwere considered. Therefore, all inferred results, like global area coverage (GAC) U cloud cover, cloud properties and radiant properties, could be intercompared. Specific emphasis could be made to the surface radiant flux densities (all radiative balance compoments), where results for different regions, like Southern America, Southern Africa, Northern America, Europe, and Indonesia, will be presented. Applying SESAT, energy flux densities, like latent and sensible heat flux densities could also be determined additionally. A statistical analysis of all results including a detailed discussion for the two spatial resolutions will close this study.

An Intelligent System Proposal for Improving the Safety and Accessibility of Public Transit by Highway

Directory of Open Access Journals (Sweden)

Carmelo R. García

2015-08-01

Full Text Available The development of public transit systems that are accessible and safe for everyone, including people with special needs, is an objective that is justified from the civic and economic points of view. Unfortunately, public transit services are conceived for people who do not have reduced physical or cognitive abilities. In this paper, we present an intelligent public transit system by highway with the goal of facilitating access and improving the safety of public transit for persons with special needs. The system is deployed using components that are commonly available in transport infrastructure, e.g., sensors, mobile communications systems, and positioning systems. In addition, the system can operate in non-urban transport contexts, e.g., isolated rural areas, where the availability of basic infrastructure, such as electricity and communications infrastructures, is not always guaranteed. To construct the system, the principles and techniques of Ubiquitous Computing and Ambient Intelligence have been employed. To illustrate the utility of the system, two cases of services rendered by the system are described: the first case involves a surveillance system to guarantee accessibility at bus stops; the second case involves a route assistant for blind people.

The new biometric access control system resembles a big electronic eye. It will be used to control access to the LHC from 2007 onwards.

CERN Multimedia

Maximilien Brice

2006-01-01

The new LHC access control systems will soon be using the latest technology: optical recognition based on iris image data. In order to gain access to the tunnel it will be your eye, not your credentials that you'll be required to show! As of September, the entrance point at Point 8 should be the first to be fitted out with iris recognition equipment. The other access shafts will then gradually be equipped one by one.

Cluster analysis of autoantibodies in 852 patients with systemic lupus erythematosus from a single center.

Science.gov (United States)

Artim-Esen, Bahar; Çene, Erhan; Şahinkaya, Yasemin; Ertan, Semra; Pehlivan, Özlem; Kamali, Sevil; Gül, Ahmet; Öcal, Lale; Aral, Orhan; Inanç, Murat

2014-07-01

Associations between autoantibodies and clinical features have been described in systemic lupus erythematosus (SLE). Herein, we aimed to define autoantibody clusters and their clinical correlations in a large cohort of patients with SLE. We analyzed 852 patients with SLE who attended our clinic. Seven autoantibodies were selected for cluster analysis: anti-DNA, anti-Sm, anti-RNP, anticardiolipin (aCL) immunoglobulin (Ig)G or IgM, lupus anticoagulant (LAC), anti-Ro, and anti-La. Two-step clustering and Kaplan-Meier survival analyses were used. Five clusters were identified. A cluster consisted of patients with only anti-dsDNA antibodies, a cluster of anti-Sm and anti-RNP, a cluster of aCL IgG/M and LAC, and a cluster of anti-Ro and anti-La antibodies. Analysis revealed 1 more cluster that consisted of patients who did not belong to any of the clusters formed by antibodies chosen for cluster analysis. Sm/RNP cluster had significantly higher incidence of pulmonary hypertension and Raynaud phenomenon. DsDNA cluster had the highest incidence of renal involvement. In the aCL/LAC cluster, there were significantly more patients with neuropsychiatric involvement, antiphospholipid syndrome, autoimmune hemolytic anemia, and thrombocytopenia. According to the Systemic Lupus International Collaborating Clinics damage index, the highest frequency of damage was in the aCL/LAC cluster. Comparison of 10 and 20 years survival showed reduced survival in the aCL/LAC cluster. This study supports the existence of autoantibody clusters with distinct clinical features in SLE and shows that forming clinical subsets according to autoantibody clusters may be useful in predicting the outcome of the disease. Autoantibody clusters in SLE may exhibit differences according to the clinical setting or population.

Is the Japanese Distribution System Becoming More Accessible to Foreign Firms?

OpenAIRE

Ralf bebenroth; Nir Kshetri; Reinhard Hunerberg

2009-01-01

Complexities in the Japanese distribution system are well-publicized. An emerging body of literature has documented recent changes in the Japanese distribution system. In this paper, it is examined whether foreign firms' accessibility to the Japanese distribution system has changed in a favorable direction in recent years. Furthermore, as foreign firms vary widely in terms of institutional barriers and complexity they face in the Japanese market, the authors also investigate the determinants ...

National Geothermal Data System: an Exemplar of Open Access to Data

Science.gov (United States)

Allison, M. L.; Richard, S. M.; Blackman, H.; Anderson, A.

2013-12-01

The National Geothermal Data System's (NGDS - www.geothermaldata.org) formal launch in 2014 will provide open access to millions of datasets, sharing technical geothermal-relevant data across the geosciences to propel geothermal development and production. With information from all of the Department of Energy's sponsored development and research projects and geologic data from all 50 states, this free, interactive tool is opening new exploration opportunities and shortening project development by making data easily discoverable and accessible. We continue to populate our prototype functional data system with multiple data nodes and nationwide data online and available to the public. Data from state geological surveys and partners includes more than 5 million records online, including 1.48 million well headers (oil and gas, water, geothermal), 732,000 well logs, and 314,000 borehole temperatures and is growing rapidly. There are over 250 Web services and another 138 WMS (Web Map Services) registered in the system as of August, 2013. Companion projects run by Boise State University, Southern Methodist University, and USGS are adding millions of additional data records. The National Renewable Energy Laboratory is managing the Geothermal Data Repository which will serve as a system node and clearinghouse for data from hundreds of DOE-funded geothermal projects. NGDS is built on the US Geoscience Information Network data integration framework, which is a joint undertaking of the USGS and the Association of American State Geologists (AASG). NGDS is fully compliant with the White House Executive Order of May 2013, requiring all federal agencies to make their data holdings publicly accessible online in open source, interoperable formats with common core and extensible metadata. The National Geothermal Data System is being designed, built, deployed, and populated primarily with grants from the US Department of Energy, Geothermal Technologies Office. To keep this operational

Effects of Job Accessibility Improved by Public Transport System: Natural Experimental Evidence from the Copenhagen Metro

DEFF Research Database (Denmark)

Pons Rotger, Gabriel Angel; Nielsen, Thomas Alexander Sick

2015-01-01

This study examines the effect of accessibility to urban jobs via a public transport system on individual earnings and commuting behaviour. The effect of improved public transport based accessibility on these outcomes is determined by exploiting the exogenous variation in access to a public rail...... and Metro system resulting from the construction of a new terminal Metro station connecting southern townships to Copenhagen city centre. The results show that public transport based job accessibility has a positive and permanent effect on individual earnings. The increase in earnings is associated...... with a change in commuting patterns as the improved access to public transport facilitates a shift from employment within the township to better paid jobs in the city centre, as well as in other suburbs of the Copenhagen Metropolitan area...

Remotely Sensed Land Imagery and Access Systems: USGS Updates

Science.gov (United States)

Lamb, R.; Pieschke, R.; Lemig, K.

2017-12-01

The U.S. Geological Survey (USGS) Earth Resources Observation and Science (EROS) Center has implemented a number of updates to its suite of remotely sensed products and distribution systems. These changes will greatly expand the availability, accessibility, and usability of the image products from USGS. As of late 2017, several new datasets are available for public download at no charge from USGS/EROS Center. These products include Multispectral Instrument (MSI) Level-1C data from the Sentinel-2B satellite, which was launched in March 2017. Along with Sentinel-2A, the Sentinel-2B images are now being distributed through USGS systems as part of a collaborative effort with the European Space Agency (ESA). The Sentinel-2 imagery is highly complementary to multispectral data collected by the USGS Landsat 7 and 8 satellites. With these two missions operating together, the potential local revisit rate can be reduced to 2-4 days. Another product addition is Resourcesat-2 data acquired over the United States by the Indian Space Research Organisation (ISRO). The Resourcesat-2 products from USGS consist of Advanced Wide Field Sensor (AWiFS) and Linear Imaging Self-Scanning Sensor Three (LISS-3) images acquired August 2016 to present. In an effort to maximize future Landsat data interoperability, including time series analysis of the 45+ year archive, the reprocessing of Collection 1 for all historical Landsat Level 1 products is nearly complete. The USGS is now working on operational release of higher-level science products to support analysis of the Landsat archive at the pixel level. Major upgrades were also completed in 2017 for several USGS data discovery and access systems, including the LandsatLook Viewer (https://landsatlook.usgs.gov/) and GloVis Tool (https://glovis.usgs.gov/). Other options are now being developed to further enhance data access and overall user experience. These future options will be discussed and community feedback will be encouraged.

Shared random access memory resource for multiprocessor real-time systems

International Nuclear Information System (INIS)

Dimmler, D.G.; Hardy, W.H. II

1977-01-01

A shared random-access memory resource is described which is used within real-time data acquisition and control systems with multiprocessor and multibus organizations. Hardware and software aspects are discussed in a specific example where interconnections are done via a UNIBUS. The general applicability of the approach is also discussed

Europa-Latinoamérica: amigos complicados. Sobre la IV EU-LAC en Viena, Austria

Directory of Open Access Journals (Sweden)

Gerhard Drekonja-Kornat

2014-06-01

Full Text Available Para los presidentes latinoamericanos, las cumbres ya son rutina. Para Viena, la anfitriona de la IV reunión EU-LAC que se realizó del 11 al 13 de mayo de 2006, esta cumbre fue el acontecimiento del siglo. Se podría decir que fue la continuación del Congreso de Viena de 1815. Adecuadamente acicalada, se presentó la capital austriaca, a la cual después de Río, Madrid y Guadalajara, le tocó organizar la cuarta Cumbre de Jefes de Estado y de Gobierno de la Unión Europea, América Latina y el Caribe. Puesto que también se encontraban presentes los representantes de los países adherentes y candidatos a ingresar a la Unión –incluso el primer ministro de Turquía, R. T. Erdogan estuvo presente–, se tomó la tradicional “foto familiar” con 60 participantes.

A remark on accessibility

International Nuclear Information System (INIS)

Wu, Xinxing; Wang, Jianjun

2016-01-01

Highlights: • Obtain some characteristics of accessibility and Kato’s chaos. • Answer negatively a question in [Li R, Wang H, Zhao Y. Kato’s chaos in duopoly games. Chaos Solit Fract 2016;84:69–72]. • A dynamical system is indecomposable if and only if it is weakly transitive. - Abstract: This note obtains some characteristics of accessibility and Kato’s chaos. Applying these results, an accessible dynamical system whose product system is not accessible is constructed, giving a negative answer to a question in [Li R, Wang H, Zhao Y. Kato’s chaos in duopoly games. Chaos Solit Fract 2016;84:69–72]. Besides, it is proved that every transitive interval self-map is accessible.

Access Request Trustworthiness in Weighted Access Control Framework

Institute of Scientific and Technical Information of China (English)

WANG Lun-wei; LIAO Xiang-ke; WANG Huai-min

2005-01-01

Weighted factor is given to access control policies to express the importance of policy and its effect on access control decision. According to this weighted access control framework, a trustworthiness model for access request is also given. In this model, we give the measure of trustworthiness factor to access request, by using some idea of uncertainty reasoning of expert system, present and prove the parallel propagation formula of request trustworthiness factor among multiple policies, and get the final trustworthiness factor to decide whether authorizing. In this model, authorization decision is given according to the calculation of request trustworthiness factor, which is more understandable, more suitable for real requirement and more powerful for security enhancement than traditional methods. Meanwhile the finer access control granularity is another advantage.

Multiple Coaxial Catheter System for Reliable Access in Interventional Stroke Therapy

International Nuclear Information System (INIS)

Kulcsar, Zsolt; Yilmaz, Hasan; Bonvin, Christophe; Lovblad, Karl O.; Ruefenacht, Daniel A.

2010-01-01

In some patients with acute cerebral vessel occlusion, navigating mechanical thrombectomy systems is difficult due to tortuous anatomy of the aortic arch, carotid arteries, or vertebral arteries. Our purpose was to describe a multiple coaxial catheter system used for mechanical revascularization that helps navigation and manipulations in tortuous vessels. A triple or quadruple coaxial catheter system was built in 28 consecutive cases presenting with acute ischemic stroke. All cases were treated by mechanical thrombectomy with the Penumbra System. In cases of unsuccessful thrombo-aspiration, additional thrombolysis or angioplasty with stent placement was used for improving recanalization. The catheter system consisted of an outermost 8-Fr and an intermediate 6-Fr guiding catheter, containing the inner Penumbra reperfusion catheters. The largest, 4.1-Fr, reperfusion catheter was navigated over a Prowler Select Plus microcatheter. The catheter system provided access to reach the cerebral lesions and provided stability for the mechanically demanding manipulations of thromboaspiration and stent navigation in all cases. Apart from their mechanical role, the specific parts of the system could also provide access to different types of interventions, like carotid stenting through the 8-Fr guiding catheter and intracranial stenting and thrombolysis through the Prowler Select Plus microcatheter. In this series, there were no complications related to the catheter system. In conclusion, building up a triple or quadruple coaxial system proved to be safe and efficient in our experience for the mechanical thrombectomy treatment of acute ischemic stroke.

Interoperable Access to Near Real Time Ocean Observations with the Observing System Monitoring Center

Science.gov (United States)

O'Brien, K.; Hankin, S.; Mendelssohn, R.; Simons, R.; Smith, B.; Kern, K. J.

2013-12-01

The Observing System Monitoring Center (OSMC), a project funded by the National Oceanic and Atmospheric Administration's Climate Observations Division (COD), exists to join the discrete 'networks' of In Situ ocean observing platforms -- ships, surface floats, profiling floats, tide gauges, etc. - into a single, integrated system. The OSMC is addressing this goal through capabilities in three areas focusing on the needs of specific user groups: 1) it provides real time monitoring of the integrated observing system assets to assist management in optimizing the cost-effectiveness of the system for the assessment of climate variables; 2) it makes the stream of real time data coming from the observing system available to scientific end users into an easy-to-use form; and 3) in the future, it will unify the delayed-mode data from platform-focused data assembly centers into a standards- based distributed system that is readily accessible to interested users from the science and education communities. In this presentation, we will be focusing on the efforts of the OSMC to provide interoperable access to the near real time data stream that is available via the Global Telecommunications System (GTS). This is a very rich data source, and includes data from nearly all of the oceanographic platforms that are actively observing. We will discuss how the data is being served out using a number of widely used 'web services' (including OPeNDAP and SOS) and downloadable file formats (KML, csv, xls, netCDF), so that it can be accessed in web browsers and popular desktop analysis tools. We will also be discussing our use of the Environmental Research Division's Data Access Program (ERDDAP), available from NOAA/NMFS, which has allowed us to achieve our goals of serving the near real time data. From an interoperability perspective, it's important to note that access to the this stream of data is not just for humans, but also for machine-to-machine requests. We'll also delve into how we

ATLAS, an integrated structural analysis and design system. Volume 4: Random access file catalog

Science.gov (United States)

Gray, F. P., Jr. (Editor)

1979-01-01

A complete catalog is presented for the random access files used by the ATLAS integrated structural analysis and design system. ATLAS consists of several technical computation modules which output data matrices to corresponding random access file. A description of the matrices written on these files is contained herein.

[Testicular testosterone production in male mice of inbred strains PT and CBA/Lac after a long-term period of stable social hierarchy].

Science.gov (United States)

Osadchuk, L V; Gutorova, N V; Kleshchev, M A

2014-04-01

Social dominance can alter testicular testosterone production, although there is pronounced variability in the relationship between social status and pattern of the testosterone response. The study designed to investigate how a long-term period of stable social hierarchy effects on testicular testosterone production in male mice of inbred strains PT and CBA/Lac. Paired males of different genotypes were housed together for 32 days beginning 38 day of age. Dyadic interactions of males generated dominance-subordination relationships during the first day after a social group has been produced and the social rank of each opponent was assessed by asymmetry in agonistic behaviour. Serum level of testosterone and its testicular content were evaluated in male mice of both inbred strains at 70 day of age after pair housing. Control animals were age- and genotype-matched single males that were housed in conventional cages. After a long-term period of pair housing, the serum testosterone level and its testicular content in males of both PT and CBA/Lac strains were not significantly different from the control. There were no significant differences in androgenic parameters between social ranks in male mice of both strains. The results indicate that in laboratory mice the pattern of testicular testosterone response to social hierarchy determined by a social situation, for example, a stability of social interactions, when the importance of aggressive competition for rank is minimal.

First Experiences Using XACML for Access Control in Distributed Systems

Science.gov (United States)

Lorch, Marcus; Proctor, Seth; Lepro, Rebekah; Kafura, Dennis; Shah, Sumit

2003-01-01

Authorization systems today are increasingly complex. They span domains of administration, rely on many different authentication sources, and manage permissions that can be as complex as the system itself. Worse still, while there are many standards that define authentication mechanisms, the standards that address authorization are less well defined and tend to work only within homogeneous systems. This paper presents XACML, a standard access control language, as one component of a distributed and inter-operable authorization framework. Several emerging systems which incorporate XACML are discussed. These discussions illustrate how authorization can be deployed in distributed, decentralized systems. Finally, some new and future topics are presented to show where this work is heading and how it will help connect the general components of an authorization system.

Security Guidelines for the Development of Accessible Web Applications through the implementation of intelligent systems

Directory of Open Access Journals (Sweden)

Luis Joyanes Aguilar

2009-12-01

Full Text Available Due to the significant increase in threats, attacks and vulnerabilities that affect the Web in recent years has resulted the development and implementation of pools and methods to ensure security measures in the privacy, confidentiality and data integrity of users and businesses. Under certain circumstances, despite the implementation of these tools do not always get the flow of information which is passed in a secure manner. Many of these security tools and methods cannot be accessed by people who have disabilities or assistive technologies which enable people to access the Web efficiently. Among these security tools that are not accessible are the virtual keyboard, the CAPTCHA and other technologies that help to some extent to ensure safety on the Internet and are used in certain measures to combat malicious code and attacks that have been increased in recent times on the Web. Through the implementation of intelligent systems can detect, recover and receive information on the characteristics and properties of the different tools and hardware devices or software with which the user is accessing a web application and through analysis and interpretation of these intelligent systems can infer and automatically adjust the characteristics necessary to have these tools to be accessible by anyone regardless of disability or navigation context. This paper defines a set of guidelines and specific features that should have the security tools and methods to ensure the Web accessibility through the implementation of intelligent systems.

National Geothermal Data System: Open Access to Geoscience Data, Maps, and Documents

Science.gov (United States)

Caudill, C. M.; Richard, S. M.; Musil, L.; Sonnenschein, A.; Good, J.

2014-12-01

The U.S. National Geothermal Data System (NGDS) provides free open access to millions of geoscience data records, publications, maps, and reports via distributed web services to propel geothermal research, development, and production. NGDS is built on the US Geoscience Information Network (USGIN) data integration framework, which is a joint undertaking of the USGS and the Association of American State Geologists (AASG), and is compliant with international standards and protocols. NGDS currently serves geoscience information from 60+ data providers in all 50 states. Free and open source software is used in this federated system where data owners maintain control of their data. This interactive online system makes geoscience data easily discoverable, accessible, and interoperable at no cost to users. The dynamic project site http://geothermaldata.org serves as the information source and gateway to the system, allowing data and applications discovery and availability of the system's data feed. It also provides access to NGDS specifications and the free and open source code base (on GitHub), a map-centric and library style search interface, other software applications utilizing NGDS services, NGDS tutorials (via YouTube and USGIN site), and user-created tools and scripts. The user-friendly map-centric web-based application has been created to support finding, visualizing, mapping, and acquisition of data based on topic, location, time, provider, or key words. Geographic datasets visualized through the map interface also allow users to inspect the details of individual GIS data points (e.g. wells, geologic units, etc.). In addition, the interface provides the information necessary for users to access the GIS data from third party software applications such as GoogleEarth, UDig, and ArcGIS. A redistributable, free and open source software package called GINstack (USGIN software stack) was also created to give data providers a simple way to release data using

The limited streamer tubes system for the SLD warm iron calorimeter

International Nuclear Information System (INIS)

Benvenuti, A.C.; Camanzi, B.; Piemontese, L.; Zucchelli, P.; Calcaterra, A.; De Sangro, R.; De Simone, P.; De Simone, S.; Gallinaro, M.; Peruzzi, I.; Piccolo, M.; Bacchetta, N.; Bisello, D.; Castro, A.; Galvagni, S.; Loreti, M.; Pescara, L.; Wyss, J.; Battiston, R.; Biasini, M.; Bilei, G.M.; Checcucci, B; Mancinelli, G.; Mantovani, G.; Pauluzzi, M.; Santocchia, A.; Servoli, L.; Carpinelli, M.; Castaldi, R.; Cazzola, U.; Dell'Orso, R.; Pieroni, E.; Vannini, C.; Verdini, P.G.; Byers, B.L.; Escalera, J.; Kharakh, D.; Messner, R.L.; Zdarko, R.W.; Johnson, J.R.

1992-01-01

The SLD detector at the Stanford Linear Accelerator Center is a general purpose device for studying e + ε - interaction at the Z 0 . The SLD calorimeter system consists of two parts: a lead Liquid Argon Calorimeter (LAC) with both electromagnetic (22 radiation lengths) and hadronic sections (2.8 absorption lengths) housed inside the coil, and the Warm Ion limited streamer tubes Calorimeter (WIC) outside the coil which uses as radiator the iron of the flux return for the magnetic field. The WIC completes the measurement of the hadronic shower energy (∼85% on average is contained in the LAC) and it provides identification and tracking for muons over 99% of the solid angle. In this note we report on the construction, test and commissioning of such a large system

ICSW2AN : An Inter-vehicle Communication System Using Mobile Access Point over Wireless Wide Area Networks

Science.gov (United States)

Byun, Tae-Young

This paper presents a prototype of inter-vehicle communication system using mobile access point that internetworks wired or wireless LAN and wireless WAN anywhere. Implemented mobile access point can be equipped with various wireless WAN interfaces such as WCDMA and HSDPA. Mobile access point in the IP mechanism has to process connection setup procedure to one wireless WAN. To show the applicability of the mobile access point to inter-vehicle communication, a simplified V2I2V-based car communication system called ICSW2AN is implemented to evaluate major performance metrics by road test. In addition, results of road test for traffic information service are investigated in view of RTT, latency and server processing time. The experimental result indicates that V2I2V-based car communication system sufficiently can provide time-tolerant traffic information to moving vehicles while more than two mobile devices in restricted spaces such as car, train and ship access wireless Internet simultaneously.

Demystifying Open Access

International Nuclear Information System (INIS)

Mele, Salvatore

2007-01-01

The tenets of Open Access are to grant anyone, anywhere and anytime free access to the results of scientific research. HEP spearheaded the Open Access dissemination of scientific results with the mass mailing of preprints in the pre-WWW era and with the launch of the arXiv preprint system at the dawn of the '90s. The HEP community is now ready for a further push to Open Access while retaining all the advantages of the peer-review system and, at the same time, bring the spiralling cost of journal subscriptions under control. I will present a possible plan for the conversion to Open Access of HEP peer-reviewed journals, through a consortium of HEP funding agencies, laboratories and libraries: SCOAP3 (Sponsoring Consortium for Open Access Publishing in Particle Physics). SCOAP3 will engage with scientific publishers towards building a sustainable model for Open Access publishing, which is as transparent as possible for HEP authors. The current system in which journals income comes from subscription fees is replaced with a scheme where SCOAP3 compensates publishers for the costs incurred to organise the peer-review service and give Open Access to the final version of articles. SCOAP3 will be funded by all countries active in HEP under a 'fair share' scenario, according to their production of HEP articles. In this talk I will present a short overview of the history of Open Access in HEP, the details of the SCOAP3 model and the outlook for its implementation.

Ultrasound-assisted synthesis of 2,4-thiazolidinedione and rhodanine derivatives catalyzed by task-specific ionic liquid: [TMG][Lac].

Science.gov (United States)

Suresh; Sandhu, Jagir Singh

2013-03-03

Synthesized arylidene derivatives of rhodanine and 2,4-thiazolidiendione have potent pharmacological activities, and these are also key substrates for the preparation of clinically used antidiabetics. Some 1,1,3,3-tetramethylguanidine-based task-specific ionic liquids (TSILs) 1a-1e were prepared and employed to the catalyzed solvent-free Knoevenagel condensation of 2,4-thiazolidinedione 3a and rhodanine 3b with a variety of aldehydes. Best results were obtained with 1,1,3,3-tetramethylguanidine lactate ([TMG][Lac]) 1c. The TSIL used can be easily recovered and recycled, yielding products 4-5 in excellent yields under ultrasonic environment without the formation of any side products or toxic waste.

De Paris à Lyon. Les mutations éditoriales du «Lancelot du Lac»

Directory of Open Access Journals (Sweden)

Gaëlle Burg

2015-07-01

Full Text Available Lancelot du Lac est le premier roman arthurien imprimé à la Renais­sance. Dans sa première édition parue en 1488, qui réunit deux imprimeurs (Jean Le Bourgeois à Rouen et Jean Du Pré à Paris, un découpage et un prologue inédits sont ajoutés par le remanieur. Le texte sera réédité six fois par divers imprimeurs-libraires parisiens jusqu’en 1533. L’édition de luxe d’Antoine Vérard (1494, destinée au roi Charles VIII, présente d’importantes modifications effectuées dans un but commercial. Après une longue période d’accalmie qui signe le début du déclin de la vogue des romans de chevalerie médiévaux, Benoît Rigaud publie à Lyon, sous une forme considérablement abrégée, la dernière édition connue du Lancelot au XVIe siècle (1591. Si elle ne présente que peu d’intérêt littéraire, elle apporte cependant des informations concernant les pratiques éditoriales et les goûts du  lecteur de la fin du XVIe siècle. De Paris à Lyon, entre renaissance et déclin, le parcours éditorial d’un incontournable roman arthurien.Lancelot du Lac is the editio princeps of an Arthurian romance in Renaissance France. The first edition in 1488, which brings together two printers (Jean Le Bourgeois from Rouen and Jean Du Pré from Paris, offers original arrangement and prologue added by the compositor. The text will be published six times by various printers and booksellers in Paris until 1533. The luxurious edition from Antoine Vérard (1494 dedicated to King Charles VIII provides interesting transformations in commercial purposes. After a long time without edition, showing the beginning of chivalry literature’s decline, Benoît Rigaud publish in Lyon, in a greatly abbreviated form, the last known edition of Lancelot in the XVIth century (1591. If it presents no literary interest, it provides nevertheless informations about editorial practices and reader’s tastes from the end of Renaissance France. From Paris to

Manoomin: place-based research with Native American students on wild rice lakes on the Fond du Lac Band of Lake Superior Chippewa Reservation, northern Minnesota

Science.gov (United States)

Ito, E.; Myrbo, A.; Dalbotten, D. M.; Pellerin, H.; Greensky, L.; Howes, T.; Wold, A.; McEathron, M. A.; Shanker, V.

2010-12-01

The manoomin project is a collaboration between Fond du Lac Tribal and Community College (Cloquet, MN), the Reservation’s Resource Management Division, and the University of Minnesota funded by the NSF GEO-OEDG Program. It builds on a successful seven-year history of collaboration between these parties, including regular science camps (gidaakiimanaanimigawig, Our Earth Lodge) for students of a wide range of ages. We are working as a team with Native students to study the history of wild rice (manoomin; Zizania palustris), a culturally important resource, growing on Reservation lakes. The joint project takes two main approaches: study of sediment core samples collected from Reservation lakes; and the collection of traditional knowledge about wild rice from the Elders. Science campers collect lake cores during winter with the assistance of the U of MN’s LacCore (National Lacustrine Core Facility) and Resource Management and visit LacCore to log, split and describe cores soon thereafter. Academic mentors with a range of specialties (phytoliths, pollen, plant macrofossils, sedimentology, geochemistry, magnetics) spend 1-2 weeks during the summer with small groups of college-age (>18, many nontraditional) student interns working on a particular paleoenvironmental proxy from the sediment cores. Younger students (middle and high school) also work in small teams in half day units with the same mentors. All campers become comfortable in an academic setting, gain experience working in research labs learning and practicing techniques, and jointly interpret collective results. The continuation of the project over five years (2009-2014) will allow these students to develop relationships with scientists and to receive mentoring beyond the laboratory as they make transitions into 2- and 4-year colleges and into graduate school. Their research provides historical and environmental information that is relevant to their own land that will be used by Resource Management which is

Predictors of appendiceal perforation in an equal access system.

Science.gov (United States)

Walker, Avery; Hatch, Quinton; Drake, Thurston; Nelson, Daniel W; Fitzpatrick, Emilie; Bingham, Jason; Black, George; Maykel, Justin A; Steele, Scott R

2014-07-01

Discrepancies in socioeconomic factors have been associated with higher rates of perforated appendicitis. As an equal-access health care system theoretically removes these barriers, we aimed to determine if remaining differences in demographics, education, and pay result in disparate outcomes in the rate of perforated appendicitis. All patients undergoing appendectomy for acute appendicitis (November 2004-October 2009) at a tertiary care equal access institution were categorized by demographics and perioperative data. Rank of the sponsor was used as a surrogate for economic status. A multivariate logistic regression model was performed to determine patient and clinical characteristics associated with perforated appendicitis. A total of 680 patients (mean age 30±16 y; 37% female) were included. The majority were Caucasian (56.4% [n=384]; African Americans 5.6% [n=38]; Asians 1.9% [n=13]; and other 48.9% [n=245]) and enlisted (87.2%). Overall, 6.4% presented with perforation, with rates of 6.6%, 5.8%, and 6.7% (P=0.96) for officers, enlisted soldiers, and contractors, respectively. There was no difference in perforation when stratified by junior or senior status for either officers or enlisted (9.3% junior versus 4.40% senior officers, P=0.273; 6.60% junior versus 5.50% senior enlisted, P=0.369). On multivariate analysis, parameters such as leukocytosis and temperature, as well as race and rank were not associated with perforation (P=0.7). Only age had a correlation, with individuals aged 66-75 y having higher perforation rates (odds ratio, 1.04; 95% confidence interval, 1.02-1.05; P<0.001). In an equal-access health care system, older age, not socioeconomic factors, correlated with increased appendiceal perforation rates. Published by Elsevier Inc.

Effect of eugenol on the mutagenicity of benzo[a]pyrene and the formation of benzo[a]pyrene-DNA adducts in the X-lacZ-transgenic mouse.

NARCIS (Netherlands)

Rompelberg, C.J.M.; Steenwinkel, M.J.S.T.; Asten, J.G. van; Delft, J.H.M. van; Baan, R.A.; Verhagen, H.

1996-01-01

To study the possible reduction by eugenol of the mutagenicity and genotoxicity of benzoja]pyrene (B[a]P) in vivo, the X-lacZ-transgenic mouse strain 40.6 (Muta(TM)Mouse) was used. Male mice were fed a diet containing 0.4% (w/w) eugenol or a control diet for 58 days. On day 10, half of the mice

“Future Directions”: m-government computer systems accessed via cloud computing – advantages and possible implementations

OpenAIRE

Daniela LIŢAN

2015-01-01

In recent years, the activities of companies and Public Administration had been automated and adapted to the current information system. Therefore, in this paper, I will present and exemplify the benefits of m-government computer systems development and implementation (which can be accessed from mobile devices and which are specific to the workflow of Public Administrations) starting from the “experience” of e-government systems implementation in the context of their access and usage through ...

Access systems strategy in the accelerator complex and experimental areas

International Nuclear Information System (INIS)

Nunes, R.; Ninin, P.; Sanchez-Corral, E.; Ladzinski, T.

2012-01-01

This paper reviews the main features of the new PS Personnel Protection System (PSPSS) as well as the main milestones for its deployment during the Long Shutdown of 2013-2014. Access conditions in the PS, SPS and LHC complexes during this period shall be described as well as the upgrades and improvements that are under preparation. (authors)

Speciation in the aqueous H+/H2VO4-/H2O2/citrate system of biomedical interest.

Science.gov (United States)

Gorzsás, András; Getty, Kendra; Andersson, Ingegärd; Pettersson, Lage

2004-09-21

The speciation in the quaternary aqueous H+/H2VO4-/H2O2/citrate (Cit3-) and H+/H2VO4-/Cit3-/L-(+)-lactate (Lac-) systems has been determined at 25 degrees C in the physiological medium of 0.150 M Na(Cl). A combination of 51V NMR integral intensities and chemical shift (Bruker AMX500) as well as potentiometric data (glass electrode) have been collected and evaluated with the computer program LAKE, which is able to treat multimethod data simultaneously. The pKa-values for citric acid have been determined as 2.94, 4.34 and 5.61. Altogether six vanadate-citrate species have been found in the ternary H+/H2VO4-/Cit3- system in the pH region 2-10, only two of which are mononuclear. Reduction of vanadium(V) becomes more pronounced at pH acidic solutions limited the final model to pH > 4. In the quaternary H+/H2VO4-/Cit3-/Lac- system, two mixed-ligand species have been determined, with the compositions V2CitLac2- and V2CitLac3- (pKa = 5.0). To our knowledge, this is the first time such complexes have been reported for vanadium(V). 51V NMR chemical shifts, compositions and formation constants are given, and equilibrium conditions are illustrated in distribution diagrams as well as the fit of the model to the experimental data. When suitable, structural proposals are given, based on 13C NMR measurements and available literature data of related compounds.

Defense Hotline Allegations Concerning the Biometric Identification System for Access Omnibus Contract

National Research Council Canada - National Science Library

2008-01-01

.... According to the Strategic Services Sourcing (S3) performance work statement the purpose of the BISA is to provide a biometric base access control system that can operate in a hostile environment...

Guide on Project Web Access of SFR R and D and Technology Monitoring System

International Nuclear Information System (INIS)

Lee, Dong Uk; Won, Byung Chool; Lee, Yong Bum; Kim, Young In; Hahn, Do Hee

2008-09-01

The SFR R and D and technology monitoring system based on the MS enterprise project management is developed for systematic effective management of 'Development of Basic Key Technologies for Gen IV SFR' project which was performed under the Mid- and Long-term Nuclear R and D Program sponsored by the Ministry of Education, Science and Technology. This system is a tool for project management based on web access. Therefore this manual is a detailed guide for Project Web Access(PWA). Section 1 describes the common guide for using of system functions such as project server 2007 client connection setting, additional outlook function setting etc. The section 2 describes the guide for system administrator. It is described the guide for project management in section 3, 4

Performance enhancement of optical code-division multiple-access systems using transposed modified Walsh code

Science.gov (United States)

Sikder, Somali; Ghosh, Shila

2018-02-01

This paper presents the construction of unipolar transposed modified Walsh code (TMWC) and analysis of its performance in optical code-division multiple-access (OCDMA) systems. Specifically, the signal-to-noise ratio, bit error rate (BER), cardinality, and spectral efficiency were investigated. The theoretical analysis demonstrated that the wavelength-hopping time-spreading system using TMWC was robust against multiple-access interference and more spectrally efficient than systems using other existing OCDMA codes. In particular, the spectral efficiency was calculated to be 1.0370 when TMWC of weight 3 was employed. The BER and eye pattern for the designed TMWC were also successfully obtained using OptiSystem simulation software. The results indicate that the proposed code design is promising for enhancing network capacity.

Guide on Project Web Access of SFR R and D and Technology Monitoring System

Energy Technology Data Exchange (ETDEWEB)

Lee, Dong Uk; Won, Byung Chool; Lee, Yong Bum; Kim, Young In; Hahn, Do Hee

2008-09-15

The SFR R and D and technology monitoring system based on the MS enterprise project management is developed for systematic effective management of 'Development of Basic Key Technologies for Gen IV SFR' project which was performed under the Mid- and Long-term Nuclear R and D Program sponsored by the Ministry of Education, Science and Technology. This system is a tool for project management based on web access. Therefore this manual is a detailed guide for Project Web Access(PWA). Section 1 describes the common guide for using of system functions such as project server 2007 client connection setting, additional outlook function setting etc. The section 2 describes the guide for system administrator. It is described the guide for project management in section 3, 4.

Scheduling with Bus Access Optimization for Distributed Embedded Systems

DEFF Research Database (Denmark)

Eles, Petru; Doboli, Alex; Pop, Paul

2000-01-01

of control. Our goal is to derive a worst case delay by which the system completes execution, such that this delay is as small as possible; to generate a logically and temporally deterministic schedule; and to optimize parameters of the communication protocol such that this delay is guaranteed. We have......In this paper, we concentrate on aspects related to the synthesis of distributed embedded systems consisting of programmable processors and application-specific hardware components. The approach is based on an abstract graph representation that captures, at process level, both dataflow and the flow......, generates an efficient bus access scheme as well as the schedule tables for activation of processes and communications....

Introduction to the Personal Access Satellite System Study

Science.gov (United States)

Sue, Miles K.

1990-01-01

A recent study by the National Telecommunications and Information Administration (NTIA) has concluded that the 21st century will be the age of information in which the telecommunication infrastructure will be vital to the social and economic well being of society. To meet the challenge of the coming age, JPL has been performing studies on a personal access satellite system (PASS) for the 21st century. The PASS study can be traced back to a study in which the technical feasibility and potential applications of a high frequency, low data rate satellite system were identified using small fixed terminals. Herein, the PASS concept is described along with the strawman design. Then the key challenges are identified along with possible solutions. Finally, the plan for the future is summarized from the key results.

Genetic Relationships among Tall Coconut Palm (Cocos nucifera L. Accessions of the International Coconut Genebank for Latin America and the Caribbean (ICG-LAC, Evaluated Using Microsatellite Markers (SSRs.

Directory of Open Access Journals (Sweden)

Carina Mendes Loiola

Full Text Available The diversity and genetic relationships among two accessions of tall coconut palms collected in Brazil and seven accessions introduced from different geographic regions of the world were analyzed using 25 microsatellite primers, 19 of which were polymorphic and detected between 4 and 10 alleles per locus, with an average of 6.57. The observed and expected heterozygosity ranged from 0.25 and 0.40 in the Rennell Islands Tall (RIT accession to 0.54 and 0.62 in the Polynesian Tall (PYT accession. The analysis of genetic structure resulted in the formation of five distinct groups. The first group was formed by the accessions Brazilian Tall-Praia do Forte (BRTPF, Brazilian Tall-Merepe (BRTMe and West African Tall (WAT; the second group consisted of Malaysian Tall (MLT; the third group of RIT; the fourth group of Vanuatu Tall (VTT; and the fifth group of Rotuman Tall (RTMT, Tonga Tall (TONT and PYT. The dendrogram based on the nearest-neighbor method detected the formation of two main groups and five subgroups, indicating that the genetic relationships of the accessions are based on their geographic regions of origin. The analyses revealed genetic relationships between the accessions collected in Brazil and the accession from Africa, and among palms from South East Asia and the South Pacific, confirming the common origin of these accessions. The information obtained in this study can guide decisions on germplasm conservation activities and the efficient selection of genetically divergent parents for use in coconut breeding programs in Brazil, which are attempting to select for disease resistance, mainly to lethal yellowing, among other characteristics.

Genetic Relationships among Tall Coconut Palm (Cocos nucifera L.) Accessions of the International Coconut Genebank for Latin America and the Caribbean (ICG-LAC), Evaluated Using Microsatellite Markers (SSRs).

Science.gov (United States)

Loiola, Carina Mendes; Azevedo, Alinne Oliveira Nunes; Diniz, Leandro E C; Aragão, Wilson Menezes; Azevedo, Carlos Diego de O; Santos, Pedro Henrique A D; Ramos, Helaine Christine C; Pereira, Messias Gonzaga; Ramos, Semíramis R Ramalho

2016-01-01

The diversity and genetic relationships among two accessions of tall coconut palms collected in Brazil and seven accessions introduced from different geographic regions of the world were analyzed using 25 microsatellite primers, 19 of which were polymorphic and detected between 4 and 10 alleles per locus, with an average of 6.57. The observed and expected heterozygosity ranged from 0.25 and 0.40 in the Rennell Islands Tall (RIT) accession to 0.54 and 0.62 in the Polynesian Tall (PYT) accession. The analysis of genetic structure resulted in the formation of five distinct groups. The first group was formed by the accessions Brazilian Tall-Praia do Forte (BRTPF), Brazilian Tall-Merepe (BRTMe) and West African Tall (WAT); the second group consisted of Malaysian Tall (MLT); the third group of RIT; the fourth group of Vanuatu Tall (VTT); and the fifth group of Rotuman Tall (RTMT), Tonga Tall (TONT) and PYT. The dendrogram based on the nearest-neighbor method detected the formation of two main groups and five subgroups, indicating that the genetic relationships of the accessions are based on their geographic regions of origin. The analyses revealed genetic relationships between the accessions collected in Brazil and the accession from Africa, and among palms from South East Asia and the South Pacific, confirming the common origin of these accessions. The information obtained in this study can guide decisions on germplasm conservation activities and the efficient selection of genetically divergent parents for use in coconut breeding programs in Brazil, which are attempting to select for disease resistance, mainly to lethal yellowing, among other characteristics.

Development of Remote Monitoring and a Control System Based on PLC and WebAccess for Learning Mechatronics

Directory of Open Access Journals (Sweden)

Wen-Jye Shyr

2013-02-01

Full Text Available This study develops a novel method for learning mechatronics using remote monitoring and control, based on a programmable logic controller (PLC and WebAccess. A mechatronics module, a Web-CAM and a PLC were integrated with WebAccess software to organize a remote laboratory. The proposed system enables users to access the Internet for remote monitoring and control of the mechatronics module via a web browser, thereby enhancing work flexibility by enabling personnel to control mechatronics equipment from a remote location. Mechatronics control and long-distance monitoring were realized by establishing communication between the PLC and WebAccess. Analytical results indicate that the proposed system is feasible. The suitability of this system is demonstrated in the department of industrial education and technology at National Changhua University of Education, Taiwan. Preliminary evaluation of the system was encouraging and has shown that it has achieved success in helping students understand concepts and master remote monitoring and control techniques.

Welcome to Systems — A New Interdisciplinary Open Access Journal for Systems Science and Engineering

Directory of Open Access Journals (Sweden)

Thomas Huynh

2012-04-01

Full Text Available Natural and human-made systems abound around us. Our solar system, the human body, the food chain, and ecosystems are some examples of natural systems. Some human-made systems are transportation systems, weapon systems, computer systems, software systems, satellite communications systems, ships, missile defense systems, health care systems, the internet, financial systems, and regional economies. Understanding of natural systems is essential to the survival of the human species, which is intertwined with the survival of other species on earth. Having the knowledge and ability to build human-made systems is critical to the employment of systems that effectively serve the needs of their users. To gain such understanding and to acquire such knowledge and ability, it is necessary that cutting-edge research in systems science, systems engineering, and systems-related fields continue. This open access journal aims to achieve quick and global dissemination of results of such research. [...

Development of Decision-Making Automated System for Optimal Placement of Physical Access Control System’s Elements

Science.gov (United States)

Danilova, Olga; Semenova, Zinaida

2018-04-01

The objective of this study is a detailed analysis of physical protection systems development for information resources. The optimization theory and decision-making mathematical apparatus is used to formulate correctly and create an algorithm of selection procedure for security systems optimal configuration considering the location of the secured object’s access point and zones. The result of this study is a software implementation scheme of decision-making system for optimal placement of the physical access control system’s elements.

Risk of infection due to medical interventions via central venous catheters or implantable venous access port systems at the middle port of a three-way cock: luer lock cap vs. luer access split septum system (Q-Syte).

Science.gov (United States)

Pohl, Fabian; Hartmann, Werner; Holzmann, Thomas; Gensicke, Sandra; Kölbl, Oliver; Hautmann, Matthias G

2014-01-25

Many cancer patients receive a central venous catheter or port system prior to therapy to assure correct drug administration. Even appropriate hygienic intervention maintenance carries the risk of contaminating the middle port (C-port) of a three-way cock (TWC), a risk that increases with the number of medical interventions. Because of the complexity of the cleaning procedure with disconnection and reconnection of the standard luer lock cap (referred as "intervention"), we compared luer lock caps with a "closed access system" consisting of a luer access split septum system with regard to process optimization (work simplification, process time), efficiency (costs) and hygiene (patient safety). For determination of process optimization the workflow of an intervention according to the usual practice and risks was depicted in a process diagram. For determining the actual process costs, we analyzed use of material and time parameters per intervention and used the process parameters for programming the process into a simulation run (n = 1000) to determine the process costs as well as their differences (ACTUAL vs. NOMINAL) within the framework of a discrete event simulation.Additionally cultures were carried out at the TWC C-ports to evaluate possible contamination. With the closed access system, the mean working time of 5.5 minutes could be reduced to 2.97 minutes. The results for average process costs (labour and material costs per use) were 3.92 € for luer lock caps and 2.55 € for the closed access system. The hypothesis test (2-sample t-test, CI 0.95, p-valuerisks (related to material, surroundings, staff handling) could be reduced by 65.38%. In the present research, the closed access system with a divided split septum was superior to conventional luer lock caps. The advantage of the closed access system lies in the simplified handling for staff, which results in a reduced risk of patient infection due to improved clinical hygiene.

Study and development of a document file system with selective access

International Nuclear Information System (INIS)

Mathieu, Jean-Claude

1974-01-01

The objective of this research thesis was to design and to develop a set of software aimed at an efficient management of a document file system by using methods of selective access to information. Thus, the three main aspects of file processing (creation, modification, reorganisation) have been addressed. The author first presents the main problems related to the development of a comprehensive automatic documentation system, and their conventional solutions. Some future aspects, notably dealing with the development of peripheral computer technology, are also evoked. He presents the characteristics of INIS bibliographic records provided by the IAEA which have been used to create the files. In the second part, he briefly describes the file system general organisation. This system is based on the use of two main files: an inverse file which contains for each descriptor a list of of numbers of files indexed by this descriptor, and a dictionary of descriptor or input file which gives access to the inverse file. The organisation of these both files is then describes in a detailed way. Other related or associated files are created, and the overall architecture and mechanisms integrated into the file data input software are described, as well as various processing applied to these different files. Performance and possible development are finally discussed

U-Access: a web-based system for routing pedestrians of differing abilities

Science.gov (United States)

Sobek, Adam D.; Miller, Harvey J.

2006-09-01

For most people, traveling through urban and built environments is straightforward. However, for people with physical disabilities, even a short trip can be difficult and perhaps impossible. This paper provides the design and implementation of a web-based system for the routing and prescriptive analysis of pedestrians with different physical abilities within built environments. U-Access, as a routing tool, provides pedestrians with the shortest feasible route with respect to one of three differing ability levels, namely, peripatetic (unaided mobility), aided mobility (mobility with the help of a cane, walker or crutches) and wheelchair users. U-Access is also an analytical tool that can help identify obstacles in built environments that create routing discrepancies among pedestrians with different physical abilities. This paper discusses the system design, including database, algorithm and interface specifications, and technologies for efficiently delivering results through the World Wide Web (WWW). This paper also provides an illustrative example of a routing problem and an analytical evaluation of the existing infrastructure which identifies the obstacles that pose the greatest discrepancies between physical ability levels. U-Access was evaluated by wheelchair users and route experts from the Center for Disability Services at The University of Utah, USA.

The equipment access software for a distributed UNIX-based accelerator control system

International Nuclear Information System (INIS)

Trofimov, Nikolai; Zelepoukine, Serguei; Zharkov, Eugeny; Charrue, Pierre; Gareyte, Claire; Poirier, Herve

1994-01-01

This paper presents a generic equipment access software package for a distributed control system using computers with UNIX or UNIX-like operating systems. The package consists of three main components, an application Equipment Access Library, Message Handler and Equipment Data Base. An application task, which may run in any computer in the network, sends requests to access equipment through Equipment Library calls. The basic request is in the form Equipment-Action-Data and is routed via a remote procedure call to the computer to which the given equipment is connected. In this computer the request is received by the Message Handler. According to the type of the equipment connection, the Message Handler either passes the request to the specific process software in the same computer or forwards it to a lower level network of equipment controllers using MIL1553B, GPIB, RS232 or BITBUS communication. The answer is then returned to the calling application. Descriptive information required for request routing and processing is stored in the real-time Equipment Data Base. The package has been written to be portable and is currently available on DEC Ultrix, LynxOS, HPUX, XENIX, OS-9 and Apollo domain. ((orig.))

An API-based search system for one click access to information

NARCIS (Netherlands)

Ionita, Dan; Tax, Niek; Hiemstra, Djoerd

This paper proposes a prototype One Click access system, based on previous work in the field and the related 1CLICK-2@NTCIR10 task. The proposed solution integrates methods from into a three tier algorithm: query categorization, information extraction and output generation and offers suggestions on

Completeness and overlap in open access systems: Search engines, aggregate institutional repositories and physics-related open sources.

Science.gov (United States)

Tsay, Ming-Yueh; Wu, Tai-Luan; Tseng, Ling-Li

2017-01-01

This study examines the completeness and overlap of coverage in physics of six open access scholarly communication systems, including two search engines (Google Scholar and Microsoft Academic), two aggregate institutional repositories (OAIster and OpenDOAR), and two physics-related open sources (arXiv.org and Astrophysics Data System). The 2001-2013 Nobel Laureates in Physics served as the sample. Bibliographic records of their publications were retrieved and downloaded from each system, and a computer program was developed to perform the analytical tasks of sorting, comparison, elimination, aggregation and statistical calculations. Quantitative analyses and cross-referencing were performed to determine the completeness and overlap of the system coverage of the six open access systems. The results may enable scholars to select an appropriate open access system as an efficient scholarly communication channel, and academic institutions may build institutional repositories or independently create citation index systems in the future. Suggestions on indicators and tools for academic assessment are presented based on the comprehensiveness assessment of each system.

Android Access Control Extension

Directory of Open Access Journals (Sweden)

Anton Baláž

2015-12-01

Full Text Available The main objective of this work is to analyze and extend security model of mobile devices running on Android OS. Provided security extension is a Linux kernel security module that allows the system administrator to restrict program's capabilities with per-program profiles. Profiles can allow capabilities like network access, raw socket access, and the permission to read, write, or execute files on matching paths. Module supplements the traditional Android capability access control model by providing mandatory access control (MAC based on path. This extension increases security of access to system objects in a device and allows creating security sandboxes per application.

5 CFR 293.504 - Composition of, and access to, the Employee Medical File System.

Science.gov (United States)

2010-01-01

... Employee Medical File System. 293.504 Section 293.504 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Employee Medical File System Records § 293.504 Composition of, and access to, the Employee Medical File System. (a) All employee occupational medical records...

Experimental demonstration of 2.5 Gbit/S incoherent two-dimensional optical code division multiple access system

International Nuclear Information System (INIS)

Glesk, I.; Baby, V.; Bres, C.-S.; Xu, L.; Rand, D.; Prucnal, P.R.

2004-01-01

We demonstrated error-free operation of 4 simultaneous users in a fast frequency-hopping time-spreading optical code division multiple access system operating at 2.5 Gbit/s a Star architecture. Effective power penalty was ≤0.5dB. Novel optical code division multiple access receiver based on Terahertz Optical Asymmetric Demultiplexer was demonstrated to eliminate multiple access interference (Authors)

High security chaotic multiple access scheme for visible light communication systems with advanced encryption standard interleaving

Science.gov (United States)

Qiu, Junchao; Zhang, Lin; Li, Diyang; Liu, Xingcheng

2016-06-01

Chaotic sequences can be applied to realize multiple user access and improve the system security for a visible light communication (VLC) system. However, since the map patterns of chaotic sequences are usually well known, eavesdroppers can possibly derive the key parameters of chaotic sequences and subsequently retrieve the information. We design an advanced encryption standard (AES) interleaving aided multiple user access scheme to enhance the security of a chaotic code division multiple access-based visible light communication (C-CDMA-VLC) system. We propose to spread the information with chaotic sequences, and then the spread information is interleaved by an AES algorithm and transmitted over VLC channels. Since the computation complexity of performing inverse operations to deinterleave the information is high, the eavesdroppers in a high speed VLC system cannot retrieve the information in real time; thus, the system security will be enhanced. Moreover, we build a mathematical model for the AES-aided VLC system and derive the theoretical information leakage to analyze the system security. The simulations are performed over VLC channels, and the results demonstrate the effectiveness and high security of our presented AES interleaving aided chaotic CDMA-VLC system.

Computer network access to scientific information systems for minority universities

Science.gov (United States)

Thomas, Valerie L.; Wakim, Nagi T.

1993-08-01

The evolution of computer networking technology has lead to the establishment of a massive networking infrastructure which interconnects various types of computing resources at many government, academic, and corporate institutions. A large segment of this infrastructure has been developed to facilitate information exchange and resource sharing within the scientific community. The National Aeronautics and Space Administration (NASA) supports both the development and the application of computer networks which provide its community with access to many valuable multi-disciplinary scientific information systems and on-line databases. Recognizing the need to extend the benefits of this advanced networking technology to the under-represented community, the National Space Science Data Center (NSSDC) in the Space Data and Computing Division at the Goddard Space Flight Center has developed the Minority University-Space Interdisciplinary Network (MU-SPIN) Program: a major networking and education initiative for Historically Black Colleges and Universities (HBCUs) and Minority Universities (MUs). In this paper, we will briefly explain the various components of the MU-SPIN Program while highlighting how, by providing access to scientific information systems and on-line data, it promotes a higher level of collaboration among faculty and students and NASA scientists.

The Baker system for nuclear access authorization screening: a psychologically developed system for access screening of vendor and owner applicants at nuclear power plants

International Nuclear Information System (INIS)

Baker, E.G.; Crouter, F.L.

1985-01-01

This paper presents a comprehensive screening program for unescorted access which has proven to be highly effective in determining the intergrity, trustworthiness, socialibility, behaviors and tendencies of an employee applicant--past, present and future. This procedure, designed specifically for the nuclear industry, can be used with owner or vendor applicants, and meets or exceeds all of the NRC's requirements. The Baker system has been used for nuclear selection since 1979

On the Redshift of TeV BL Lac Objects

Energy Technology Data Exchange (ETDEWEB)

Paiano, Simona; Falomo, Renato [INAF, Osservatorio Astronomico di Padova, Vicolo dell’Osservatorio 5 I-35122 Padova (PD) (Italy); Landoni, Marco; Righi, Chiara [INAF, Osservatorio Astronomico di Brera, Via E. Bianchi 46 I-23807 Merate (Italy); Treves, Aldo [Università degli Studi dell’Insubria, Via Valleggio 11 I-22100 Como (Italy); Scarpa, Riccardo [Instituto de Astrofisica de Canarias, C/O Via Lactea, s/n E38205—La Laguna (Tenerife) (Spain)

2017-03-10

We report results of a spectroscopic campaign carried out at the 10 m Gran Telescopio Canarias for a sample of 22 BL Lac objects detected (or candidates) at TeV energies, aiming to determine or constrain their redshift. This is of fundamental importance for the interpretation of their emission models and for population studies and is also mandatory for studying the interaction of high-energy photons with the extragalactic background light using TeV sources. Optical spectra with high signal-to-noise ratios in the range 4250–10000 Å were obtained to search for faint emission or absorption lines from both the host galaxy and the nucleus. We determine a new redshift for PKS 1424+240 ( z = 0.604) and a tentative one for 1ES 0033+595 ( z = 0.467). We are able to set new spectroscopic redshift lower limits for three other sources on the basis of Mg ii and Ca ii intervening absorption features: BZB J1243+3627 ( z > 0.483), BZB J1540+8155 ( z > 0.672), and BZB 0J2323+4210 ( z > 0.267). We confirm previous redshift estimates for four blazars: S3 0218+357 ( z = 0.944), 1ES 1215+303 ( z = 0.129), W Comae ( z = 0.102), and MS 1221.8+2452 ( z = 0.218). For the remaining targets, in seven cases (S2 0109+22, 3C 66A, VER J0521+211, S4 0954+65, BZB J1120+4214, S3 1227+25, BZB J2323+4210), we do not validate the proposed redshift. Finally, for all sources of still-unknown redshift, we set a lower limit based on the minimum equivalent width of absorption features expected from the host galaxy.

Karakteristik Enzim Digesti, Protease dan Amilase, Ikan Gurami (Osphronemus gouramy Lac. pada Fase Pertumbuhan

Directory of Open Access Journals (Sweden)

Untung Susilo

2015-05-01

Full Text Available Suatu penelitian untuk mengetahui karakteristik enzim digesti, protease dan amilase pada ikan gurami, Osphronemus gouramy Lac., telah dilakukan dengan metode survey. Jumlah ikan yang digunakan untuk penelitian sebanyak 25 ekor yang dikelompokan menjadi tiga kelompok ukuran13,29, 35,86 dan 91,86 g/ekor. Hasil penelitian menunjukkan bahwa aktivitas protease digesti ikan gurami berbeda secara signifikan pada segmen usus dan pH buffer yang berbeda (P.05, namun berbeda secara signifikan diantara ukuran ikan yang berbeda (P<.05, dan aktivitas amilase tertinggi dijumpai pada ikan dengan ukuran terkecil. Kesimpulan yang dapat diambil adalah bahwa aktivitas protease dan amilase dijumpai sepanjang saluran digestinya baik pada ikan yang berukuran kecil maupun besar. Aktivitas protease umumnya tinggi pada suasana asam dan netral pada usus depan dan tengah. Aktivitas protease ikan yang berukuran besar lebih rendah dari pada ikan yang berukuran lebih kecil. Aktivitas amilase tidak terdapat perbedaan diantara segmen usus yang diuji, namun aktivitas amilase tertinggi dijumpai pada ikan dengan berat rata-rata 13,29 g/ekor

A fuzzy expert system to Trust-Based Access Control in crowdsourcing environments

Directory of Open Access Journals (Sweden)

Olusegun Folorunso

2015-07-01

Full Text Available Crowdsourcing has been widely accepted across a broad range of application areas. In crowdsourcing environments, the possibility of performing human computation is characterized with risks due to the openness of their web-based platforms where each crowd worker joins and participates in the process at any time, causing serious effect on the quality of its computation. In this paper, a combination of Trust-Based Access Control (TBAC strategy and fuzzy-expert systems was used to enhance the quality of human computation in crowdsourcing environment. A TBAC-fuzzy algorithm was developed and implemented using MATLAB 7.6.0 to compute trust value (Tvalue, priority value as evaluated by fuzzy inference system (FIS and finally generate access decision to each crowd-worker. In conclusion, the use of TBAC is feasible in improving quality of human computation in crowdsourcing environments.

Effects of Job Accessibility Improved by Public Transport System: Natural Experimental Evidence from the Copenhagen Metro

DEFF Research Database (Denmark)

Pons Rotger, Gabriel Angel; Nielsen, Thomas Alexander Sick

2015-01-01

This study examines the effect of accessibility to urban jobs via a public transport system on individual earnings and commuting behaviour. The effect of improved public transport based accessibility on these outcomes is determined by exploiting the exogenous variation in access to a public rail ...... with a change in commuting patterns as the improved access to public transport facilitates a shift from employment within the township to better paid jobs in the city centre, as well as in other suburbs of the Copenhagen Metropolitan area...

The Origin of Mutants Under Selection: How Natural Selection Mimics Mutagenesis (Adaptive Mutation)

Science.gov (United States)

Maisnier-Patin, Sophie; Roth, John R.

2015-01-01

Selection detects mutants but does not cause mutations. Contrary to this dictum, Cairns and Foster plated a leaky lac mutant of Escherichia coli on lactose medium and saw revertant (Lac+) colonies accumulate with time above a nongrowing lawn. This result suggested that bacteria might mutagenize their own genome when growth is blocked. However, this conclusion is suspect in the light of recent evidence that revertant colonies are initiated by preexisting cells with multiple copies the conjugative F′lac plasmid, which carries the lac mutation. Some plated cells have multiple copies of the simple F′lac plasmid. This provides sufficient LacZ activity to support plasmid replication but not cell division. In nongrowing cells, repeated plasmid replication increases the likelihood of a reversion event. Reversion to lac+ triggers exponential cell growth leading to a stable Lac+ revertant colony. In 10% of these plated cells, the high-copy plasmid includes an internal tandem lac duplication, which provides even more LacZ activity—sufficient to support slow growth and formation of an unstable Lac+ colony. Cells with multiple copies of the F′lac plasmid have an increased mutation rate, because the plasmid encodes the error-prone (mutagenic) DNA polymerase, DinB. Without DinB, unstable and stable Lac+ revertant types form in equal numbers and both types arise with no mutagenesis. Amplification and selection are central to behavior of the Cairns–Foster system, whereas mutagenesis is a system-specific side effect or artifact caused by coamplification of dinB with lac. Study of this system has revealed several broadly applicable principles. In all populations, gene duplications are frequent stable genetic polymorphisms, common near-neutral mutant alleles can gain a positive phenotype when amplified under selection, and natural selection can operate without cell division when variability is generated by overreplication of local genome subregions. PMID:26134316

Simulation of groundwater flow and interaction of groundwater and surface water on the Lac du Flambeau Reservation, Wisconsin

Science.gov (United States)

Juckem, Paul F.; Fienen, Michael N.; Hunt, Randall J.

2014-01-01

The Lac du Flambeau Band of Lake Superior Chippewa and Indian Health Service are interested in improving the understanding of groundwater flow and groundwater/surface-water interaction on the Lac du Flambeau Reservation (Reservation) in southwest Vilas County and southeast Iron County, Wisconsin, with particular interest in an understanding of the potential for contamination of groundwater supply wells and the fate of wastewater that is infiltrated from treatment lagoons on the Reservation. This report describes the construction, calibration, and application of a regional groundwater flow model used to simulate the shallow groundwater flow system of the Reservation and water-quality results for groundwater and surface-water samples collected near a system of waste-water-treatment lagoons. Groundwater flows through a permeable glacial aquifer that ranges in thickness from 60 to more than 200 feet (ft). Seepage and drainage lakes are common in the area and influence groundwater flow patterns on the Reservation. A two-dimensional, steady-state analytic element groundwater flow model was constructed using the program GFLOW. The model was calibrated by matching target water levels and stream base flows through the use of the parameter-estimation program, PEST. Simulated results illustrate that groundwater flow within most of the Reservation is toward the Bear River and the chain of lakes that feed the Bear River. Results of analyses of groundwater and surface-water samples collected downgradient from the wastewater infiltration lagoons show elevated levels of ammonia and dissolved phosphorus. In addition, wastewater indicator chemicals detected in three downgradient wells and a small downgradient stream indicate that infiltrated wastewater is moving southwest of the lagoons toward Moss Lake. Potential effects of extended wet and dry periods (within historical ranges) were evaluated by adjusting precipitation and groundwater recharge in the model and comparing the

Above the nominal limit performance evaluation of multiwavelength optical code-division multiple-access systems

Science.gov (United States)

Inaty, Elie; Raad, Robert; Fortier, Paul; Shalaby, Hossam M. H.

2009-03-01

We provide an analysis for the performance of a multiwavelength optical code-division multiple-access (MW-OCDMA) network when the system is working above the nominal transmission rate limit imposed by passive encoding-decoding operation. We address the problem of overlapping in such a system and how it can directly affect the bit error rate (BER). A unified mathematical framework is presented under the assumption of one-coincidence sequences with nonrepeating wavelengths. A closed form expression of the multiple access interference limited BER is provided as a function of different system parameters. Results show that the performance of the MW-OCDMA system can be critically affected when working above the nominal limit, an event that can happen when the network operates at a high transmission rate. In addition, the impact of the derived error probability on the performance of two newly proposed medium access control (MAC) protocols, the S-ALOHA and the R3T, is also investigated. It is shown that for low transmission rates, the S-ALOHA is better than the R3T, while the R3T is better at very high transmission rates. In general, it is postulated that the R3T protocol suffers a higher delay mainly because of the presence of additional modes.

A new pale-spotted species of Hypostomus Lacépède (Siluriformes: Loricariidae from the rio Tocantins and rio Xingu basins in central Brazil

Directory of Open Access Journals (Sweden)

Cláudio H. Zawadzki

Full Text Available A new species of the genus Hypostomus Lacépède (Siluriformes, Loricariidae from rio Tocantins and rio Xingu basins in central Brazil, is described. The new species is distinguished from its congeners by a unique combination of pale blotches over a darker background on head, body and fins, and conspicuous keels on head, predorsal region and lateral plates. Comments on the pale-spotted species of Hypostomus are provided.

Completeness and overlap in open access systems: Search engines, aggregate institutional repositories and physics-related open sources.

Directory of Open Access Journals (Sweden)

Ming-Yueh Tsay

Full Text Available This study examines the completeness and overlap of coverage in physics of six open access scholarly communication systems, including two search engines (Google Scholar and Microsoft Academic, two aggregate institutional repositories (OAIster and OpenDOAR, and two physics-related open sources (arXiv.org and Astrophysics Data System. The 2001-2013 Nobel Laureates in Physics served as the sample. Bibliographic records of their publications were retrieved and downloaded from each system, and a computer program was developed to perform the analytical tasks of sorting, comparison, elimination, aggregation and statistical calculations. Quantitative analyses and cross-referencing were performed to determine the completeness and overlap of the system coverage of the six open access systems. The results may enable scholars to select an appropriate open access system as an efficient scholarly communication channel, and academic institutions may build institutional repositories or independently create citation index systems in the future. Suggestions on indicators and tools for academic assessment are presented based on the comprehensiveness assessment of each system.

Massive M2M Access with Reliability Guarantees in LTE Systems

DEFF Research Database (Denmark)

Madueño, Germán Corrales; Kiilerich Pratas, Nuno; Stefanovic, Cedomir

2015-01-01

Machine-to-Machine (M2M) communications are one of the major drivers of the cellular network evolution towards 5G systems. One of the key challenges is on how to provide reliability guarantees to each accessing device in a situation in which there is a massive number of almost-simultaneous arriva...

A service-oriented data access control model

Science.gov (United States)

Meng, Wei; Li, Fengmin; Pan, Juchen; Song, Song; Bian, Jiali

2017-01-01

The development of mobile computing, cloud computing and distributed computing meets the growing individual service needs. Facing with complex application system, it's an urgent problem to ensure real-time, dynamic, and fine-grained data access control. By analyzing common data access control models, on the basis of mandatory access control model, the paper proposes a service-oriented access control model. By regarding system services as subject and data of databases as object, the model defines access levels and access identification of subject and object, and ensures system services securely to access databases.

Flexible CP-ABE Based Access Control on Encrypted Data for Mobile Users in Hybrid Cloud System

Institute of Scientific and Technical Information of China (English)

Wen-Min Li; Xue-Lei Li; Qiao-Yan Wen; Shuo Zhang; Hua Zhang

2017-01-01

In hybrid cloud computing, encrypted data access control can provide a fine-grained access method for orga-nizations to enact policies closer to organizational policies. This paper presents an improved CP-ABE (ciphertext-policy attribute-based encryption) scheme to construct an encrypted data access control solution that is suitable for mobile users in hybrid cloud system. In our improvement, we split the original decryption keys into a control key, a secret key and a set of transformation keys. The private cloud managed by the organization administrator takes charge of updating the transformation keys using the control key. It helps to handle the situation of flexible access management and attribute alteration. Meanwhile, the mobile user's single secret key remains unchanged as well as the ciphertext even if the data user's attribute has been revoked. In addition, we modify the access control list through adding the attributes with corresponding control key and transformation keys so as to manage user privileges depending upon the system version. Finally, the analysis shows that our scheme is secure, flexible and efficient to be applied in mobile hybrid cloud computing.

Multi-views storage model and access methods of conversation history in converged IP messaging system

Science.gov (United States)

Lu, Meilian; Yang, Dong; Zhou, Xing

2013-03-01

Based on the analysis of the requirements of conversation history storage in CPM (Converged IP Messaging) system, a Multi-views storage model and access methods of conversation history are proposed. The storage model separates logical views from physical storage and divides the storage into system managed region and user managed region. It simultaneously supports conversation view, system pre-defined view and user-defined view of storage. The rationality and feasibility of multi-view presentation, the physical storage model and access methods are validated through the implemented prototype. It proves that, this proposal has good scalability, which will help to optimize the physical data storage structure and improve storage performance.

Open Access Intellectual Property Systems: A Comparison to Commercial Solutions in Competitive Intelligence

Directory of Open Access Journals (Sweden)

Jan Cerny

2016-07-01

Full Text Available ICT/IS management plays an important role within the framework of innovation management, and one of the key elements of this role is the support of Competitive Intelligence in the context of innovation processes. The strategic information needs of innovation management are also directed towards different kinds of intellectual property (IP information entities and commercialization. The purpose of this paper is to define these entities and IP information systems as an important part of a company’s Competitive Intelligence Unit for competitor analysis and technology trends. The open access IP information systems will be analysed together with commercial solutions.. The aim of this paper is to underline the importance of open access IP systems compared to added value commercial solutions for competitive intelligence purposes for SMEs. The comparison will be carried out using examples of patent searches within a concrete dataset.

Multi-level access control in the data pipeline of the international supply chain system

NARCIS (Netherlands)

Pruksasri, P.; Berg, J. van den; Hofman, W.; Daskapan, S.

2013-01-01

The Seamless Integrated Data Pipeline system was proposed to the European Union in order to overcome the information quality shortcomings of the current international supply chain information exchange systems. Next to identification and authorization of stakeholders, secure access control needs to

National Geothermal Data System (USA): an Exemplar of Open Access to Data

Science.gov (United States)

Allison, M. Lee; Richard, Stephen; Blackman, Harold; Anderson, Arlene; Patten, Kim

2014-05-01

The National Geothermal Data System's (NGDS - www.geothermaldata.org) formal launch in April, 2014 will provide open access to millions of data records, sharing -relevant geoscience and longer term to land use data to propel geothermal development and production. NGDS serves information from all of the U.S. Department of Energy's sponsored development and research projects and geologic data from all 50 states, using free and open source software. This interactive online system is opening new exploration opportunities and potentially shortening project development by making data easily discoverable, accessible, and interoperable. We continue to populate our prototype functional data system with multiple data nodes and nationwide data online and available to the public. Data from state geological surveys and partners includes more than 6 million records online, including 1.72 million well headers (oil and gas, water, geothermal), 670,000 well logs, and 497,000 borehole temperatures and is growing rapidly. There are over 312 interoperable Web services and another 106 WMS (Web Map Services) registered in the system as of January, 2014. Companion projects run by Southern Methodist University and U.S. Geological Survey (USGS) are adding millions of additional data records. The DOE Geothermal Data Repository, currently hosted on OpenEI, is a system node and clearinghouse for data from hundreds of U.S. DOE-funded geothermal projects. NGDS is built on the US Geoscience Information Network (USGIN) data integration framework, which is a joint undertaking of the USGS and the Association of American State Geologists (AASG). NGDS complies with the White House Executive Order of May 2013, requiring all federal agencies to make their data holdings publicly accessible online in open source, interoperable formats with common core and extensible metadata. The National Geothermal Data System is being designed, built, deployed, and populated primarily with support from the US

Reduction of the near-far effect in mobile communication systems with Code-Division Multiple-Access

Science.gov (United States)

Purchla, Magdalena

2006-02-01

In this paper the basic methods for reducing Multiple Access Interference (MAI) and combating the near-far effect in Direct-Sequence Code-Division Multiple-Access (DS-CDMA) mobile communication systems are presented. MAI and the near-far effect are inevitable in DS-CDMA systems with quasi-orthogonal spreading sequences. An effective method of reducing MAI can increase the capacity of the system that is why so many researchers are working in this field. In this article three most important techniques of decreasing MAI are presented: power control, multiuser detection and space-time processing. There is a short introduction to each topic and one or more examples found in literature of algorithms suitable for practical applications (although not all algorithms are yet used in existing systems).

Providing Internet Access to the Ohio Career Information System for All Residents: A Feasibility Study.

Science.gov (United States)

Lewis, Morgan V.

Expanded Internet access to the Ohio Career Information System (OCIS) would provide adults in Ohio who need to or wish to make career changes with the best available information about occupations, education and training programs, and financial aid. In order to determine the feasibility of improving access without cost to users, an advisory group,…

Synergies in the Asian energy system: Climate change, energy security, energy access and air pollution

International Nuclear Information System (INIS)

Vliet, Oscar van; Krey, Volker; McCollum, David; Pachauri, Shonali; Nagai, Yu; Rao, Shilpa; Riahi, Keywan

2012-01-01

We use the MESSAGE model to examine multiple dimensions of sustainable development for three Asian regions in a set of scenarios developed for the Asian Modelling Exercise. Using climate change mitigation as a starting point for the analysis, we focus on the interaction of climate and energy with technology choice, energy security, energy access, and air pollution, which often have higher policy priority than climate change. Stringent climate policies drive the future energy supply in Asia from being dominated by coal and oil to a more diversified system based mostly on natural gas, coal with CCS, nuclear and renewable energy. The increase in diversity helps to improve the energy security of individual countries and regions. Combining air pollution control policies and universal energy access policies with climate policy can further help to reduce both outdoor and indoor air pollution related health impacts. Investments into the energy system must double by 2030 to achieve stringent climate goals, but are largely offset by lower costs for O and M and air pollution abatement. Strong focus on end-use efficiency also helps lowering overall total costs and allows for limiting or excluding supply side technologies from the mitigation portfolio. Costs of additional energy access policies and measures are a small fraction of total energy system costs. - Highlights: ► Half of added investments in energy offset by lower costs for O and M and air pollution. ► Costs for achieving universal energy access much smaller than energy system costs. ► Combined emissions and access policies further reduce air pollution impacts on health. ► Strong focus on end-use efficiency allows for more flexibility on energy sources. ► Stringent climate policy can improve energy security of Asian regions.

Complete Genomes of Bacillus coagulans S-lac and Bacillus subtilis TO-A JPC, Two Phylogenetically Distinct Probiotics.

Science.gov (United States)

Khatri, Indu; Sharma, Shailza; Ramya, T N C; Subramanian, Srikrishna

2016-01-01

Several spore-forming strains of Bacillus are marketed as probiotics due to their ability to survive harsh gastrointestinal conditions and confer health benefits to the host. We report the complete genomes of two commercially available probiotics, Bacillus coagulans S-lac and Bacillus subtilis TO-A JPC, and compare them with the genomes of other Bacillus and Lactobacillus. The taxonomic position of both organisms was established with a maximum-likelihood tree based on twenty six housekeeping proteins. Analysis of all probiotic strains of Bacillus and Lactobacillus reveal that the essential sporulation proteins are conserved in all Bacillus probiotic strains while they are absent in Lactobacillus spp. We identified various antibiotic resistance, stress-related, and adhesion-related domains in these organisms, which likely provide support in exerting probiotic action by enabling adhesion to host epithelial cells and survival during antibiotic treatment and harsh conditions.

75 FR 4101 - Enterprise Income Verification (EIV) System User Access Authorization Form and Rules of Behavior...

Science.gov (United States)

2010-01-26

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5376-N-05] Enterprise Income Verification (EIV) System User Access Authorization Form and Rules of Behavior and User Agreement AGENCY... Access, Authorization Form and Rules Of Behavior and User Agreement. OMB Approval Number: 2577-New. Form...

Design and Implementation of a Web-based Monitoring System by using EPICS Channel Access Protocol

International Nuclear Information System (INIS)

An, Eun Mi; Song, Yong Gi

2009-01-01

Proton Engineering Frontier Project (PEFP) has developed a 20MeV proton accelerator, and established a distributed control system based on EPICS for sub-system components such as vacuum unit, beam diagnostics, and power supply system. The control system includes a real-time monitoring and alarm functions. From the aspect of a efficient maintenance of a control system and a additional extension of subsystems, EPICS software framework was adopted. In addition, a control system should be capable of providing an easy access for users and a real-time monitoring on a user screen. Therefore, we have implemented a new web-based monitoring server with several libraries. By adding DB module, the new IOC web monitoring system makes it possible to monitor the system through the web. By integrating EPICS Channel Access (CA) and Database libraries into a Database module, the web-based monitoring system makes it possible to monitor the sub-system status through user's internet browser. In this study, we developed a web based monitoring system by using EPICS IOC (Input Output Controller) with IBM server

Return Migrants’ Experience of Access to Care in Corrupt Healthcare Systems: The Bosnian Example

Directory of Open Access Journals (Sweden)

Line Neerup Handlos

2016-09-01

Full Text Available Equal and universal access to healthcare services is a core priority for a just health system. A key societal determinant seen to create inequality in access to healthcare is corruption in the healthcare system. How return migrants’ access to healthcare is affected by corruption is largely unstudied, even though return migrants may be particularly vulnerable to problems related to corruption due to their period of absence from their country of origin. This article investigates how corruption in the healthcare sector affects access to healthcare for refugees who repatriated to Bosnia, a country with a high level of corruption, from Denmark, a country with a low level of corruption. The study is based on 18 semi-structured interviews with 33 refugees who returned after long-term residence in Denmark. We found that the returned refugees faced greater problems with corruption than was the case for those who had not left the country, as doctors considered them to be better endowed financially and therefore demanded larger bribes from them than they did from those who had remained in Bosnia. Moreover, during their stay abroad the returnees had lost the connections that could have helped them sidestep the corruption. Returned refugees are thus particularly vulnerable to the effects of corruption.

Return Migrants’ Experience of Access to Care in Corrupt Healthcare Systems: The Bosnian Example

Science.gov (United States)

Neerup Handlos, Line; Fog Olwig, Karen; Bygbjerg, Ib Christian; Norredam, Marie

2016-01-01

Equal and universal access to healthcare services is a core priority for a just health system. A key societal determinant seen to create inequality in access to healthcare is corruption in the healthcare system. How return migrants’ access to healthcare is affected by corruption is largely unstudied, even though return migrants may be particularly vulnerable to problems related to corruption due to their period of absence from their country of origin. This article investigates how corruption in the healthcare sector affects access to healthcare for refugees who repatriated to Bosnia, a country with a high level of corruption, from Denmark, a country with a low level of corruption. The study is based on 18 semi-structured interviews with 33 refugees who returned after long-term residence in Denmark. We found that the returned refugees faced greater problems with corruption than was the case for those who had not left the country, as doctors considered them to be better endowed financially and therefore demanded larger bribes from them than they did from those who had remained in Bosnia. Moreover, during their stay abroad the returnees had lost the connections that could have helped them sidestep the corruption. Returned refugees are thus particularly vulnerable to the effects of corruption. PMID:27657096

Return Migrants' Experience of Access to Care in Corrupt Healthcare Systems: The Bosnian Example.

Science.gov (United States)

Neerup Handlos, Line; Fog Olwig, Karen; Bygbjerg, Ib Christian; Norredam, Marie

2016-09-19

Equal and universal access to healthcare services is a core priority for a just health system. A key societal determinant seen to create inequality in access to healthcare is corruption in the healthcare system. How return migrants' access to healthcare is affected by corruption is largely unstudied, even though return migrants may be particularly vulnerable to problems related to corruption due to their period of absence from their country of origin. This article investigates how corruption in the healthcare sector affects access to healthcare for refugees who repatriated to Bosnia, a country with a high level of corruption, from Denmark, a country with a low level of corruption. The study is based on 18 semi-structured interviews with 33 refugees who returned after long-term residence in Denmark. We found that the returned refugees faced greater problems with corruption than was the case for those who had not left the country, as doctors considered them to be better endowed financially and therefore demanded larger bribes from them than they did from those who had remained in Bosnia. Moreover, during their stay abroad the returnees had lost the connections that could have helped them sidestep the corruption. Returned refugees are thus particularly vulnerable to the effects of corruption.

Multigigabit W-Band (75–110 GHz) Bidirectional Hybrid Fiber-Wireless Systems in Access Networks

DEFF Research Database (Denmark)

Pang, Xiaodan; Lebedev, Alexander; Vegas Olmos, Juan José

2014-01-01

compare the transmission performances in terms of achievable wireless distances with and without using a high-frequency electrical power amplifier at the wireless transmitter. A downlink 16-Gbit/s QPSK signal and an uplink 1.25-Gbit/s ASK signal transmission over the two implementations are experimentally......We experimentally demonstrate multigigabit capacity bidirectional hybrid fiber-wireless systems with RF carrier frequencies at the W-band (75-110 GHz) that enables the seamless convergence between wireless and fiber-optic data transmission systems in access networks. In this study, we evaluate...... the transmission performances in two scenarios: a fiber-wireless access link that directly provide high-speed connections to wireless end users, and a fiber-wireless-fiber signal relay where a high capacity wireless link can be used to bridge two access fiber spans over physical obstacles. In both scenarios, we...

The Principle of Non-Refoulement and Access to Asylum System: Two Sides of the Same Coin

Directory of Open Access Journals (Sweden)

Goranka Lalić Novak

2015-12-01

Full Text Available The European Union and other countries on the Balkan route for migrants have recorded a large increase in the number of asylum seekers. In parallel with the increased number of refugees trying to enter the territory of the EU, measures for migration management have tightened, and the right to asylum at the level of the Member States has been interpreted more and more restrictive. Search for protection from persecution has become a reason for closing borders and disabling access to territory and asylum system. However, access to asylum system is the first step in the realization of the right to asylum as guaranteed by international, European and national law. In addition to allowing access to territory and asylum system, which implies an obligation of states to accept refugees in order to confirm the need for international protection in a fair and efficient procedure, the states are obliged to respect the principle of non-refoulement. The aim of this paper is to clarify the connection between providing access to asylum system and respect for the principle of non-refoulement. Analysis in the paper was done by legal-dogmatic method of research and interpretation of legal acts and other authorities, as well as of UNHCR relevant recommendations and documents. The assumption is that without the provision of access to territory and asylum system the principle of non-refoulement cannot be respected. Apart from the international refugee law and doctrinal interpretations, it derives from the practice of the European Court of Human Rights regarding the prohibition of torture or other inhuman treatment or punishment guaranteed by the Convention for the Protection of Human Rights and Fundamental Freedoms. The conclusion is that the states must take into account international and European standards regarding the protection of the principle of non-refoulement when considering the introduction of new measures to manage migration movements.

The NASA Astrophysics Data System Free Access to the Astronomical Literature On-Line and through Email

CERN Document Server

Eichhorn, G; Grant, C S; Kurtz, M J; Murray, S S

2001-01-01

The Astrophysics Data System (ADS) provides access to the astronomical literature through the World Wide Web. It is a NASA funded project and access to all the ADS services is free to everybody world-wide.The ADS Abstract Service allows the searching of four databases with abstracts in Astronomy, Instrumentation, Physics/Geophysics, and the LANL Preprints with a total of over 2.2 million references. The system also provides access to reference and citation information, links to on-line data, electronic journal articles, and other on-line information. The ADS Article Service contains the articles for most of the astronomical literature back to volume 1. It contains the scanned pages of all the major journals (Astrophysical Journal, Astronomical Journal, Astronomy & Astrophysics, Monthly Notices of the Royal Astronomical Society, and Solar Physics), as well as most smaller journals back to volume 1. The ADS can be accessed through any web browser without signup or login. Alternatively an email interface is ...

Professional Access 2013 programming

CERN Document Server

Hennig, Teresa; Hepworth, George; Yudovich, Dagi (Doug)

2013-01-01

Authoritative and comprehensive coverage for building Access 2013 Solutions Access, the most popular database system in the world, just opened a new frontier in the Cloud. Access 2013 provides significant new features for building robust line-of-business solutions for web, client and integrated environments.  This book was written by a team of Microsoft Access MVPs, with consulting and editing by Access experts, MVPs and members of the Microsoft Access team. It gives you the information and examples to expand your areas of expertise and immediately start to develop and upgrade projects. Exp

Access control and interlock system at the Advanced Photon Source

International Nuclear Information System (INIS)

Forrestal, J.; Hogrefe, R.; Knott, M.; McDowell, W.; Reigle, D.; Solita, L.; Koldenhoven, R.; Haid, D.

1997-01-01

The Advanced Photon Source (APS) consists of a linac, position accumulator ring (PAR), booster synchrotron, storage ring, and up to 70 experimental beamlines. The Access Control and Interlock System (ACIS) utilizes redundant programmable logic controllers (PLCs) and a third hard-wired chain to protect personnel from prompt radiation generated by the linac, PAR, synchrotron, and storage ring. This paper describes the ACIS's design philosophy, configuration, hardware, functionality, validation requirements, and operational experience

Design and Implementation of File Access and Control System Based on Dynamic Web

Institute of Scientific and Technical Information of China (English)

GAO Fuxiang; YAO Lan; BAO Shengfei; YU Ge

2006-01-01

A dynamic Web application, which can help the departments of enterprise to collaborate with each other conveniently, is proposed. Several popular design solutions are introduced at first. Then, dynamic Web system is chosen for developing the file access and control system. Finally, the paper gives the detailed process of the design and implementation of the system, which includes some key problems such as solutions of document management and system security. Additionally, the limitations of the system as well as the suggestions of further improvement are also explained.