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Sample records for access pressure-flow monitoring

  1. A Meta-analysis of randomized clinical trials assessing hemodialysis access thrombosis based on access flow monitoring: Where do we stand?

    Science.gov (United States)

    Muchayi, Timothy; Salman, Loay; Tamariz, Leonardo J; Asif, Arif; Rizvi, Abid; Lenz, Oliver; Vazquez-Padron, Roberto I.; Tabbara, Marwan; Contreras, Gabriel

    2015-01-01

    The National Kidney Foundation Kidney Disease Outcomes Quality Initiative recommends the routine use of hemodialysis arteriovenous (AV) access surveillance to detect hemodynamically significant stenoses and appropriately correct them to reduce the incidence of thrombosis and to improve accesses patency rates. Access blood flow monitoring is considered as one of the preferred surveillance method for both AV fistulas (AVF) and AV grafts (AVG); however, published studies have reported conflicting results of its utility that led healthcare professionals to doubt the benefits of this surveillance method. We performed a meta-analysis of the published randomized controlled trials (RCTs) of AV access surveillance using access blood flow monitoring. Our hypothesis was that access blood flow monitoring lowers the risk of AV access thrombosis and that the outcome differs between AVF and AVG. The estimated overall pooled risk ratio (RR) of thrombosis was 0.87 (95% confidence interval [CI], 0.67 to 1.13) favoring access blood flow monitoring. The pooled RR of thrombosis were 0.64 (95% CI, 0.41 to 1.01) and 1.06 (95% CI, 0.77 to 1.46) in the subgroups of only AVF and only AVG, respectively. Our results added to the uncertainty of access blood flow monitoring as a surveillance method of hemodialysis accesses. PMID:25644548

  2. Apparatus for monitoring two-phase flow

    Science.gov (United States)

    Sheppard, John D.; Tong, Long S.

    1977-03-01

    A method and apparatus for monitoring two-phase flow is provided that is particularly related to the monitoring of transient two-phase (liquid-vapor) flow rates such as may occur during a pressurized water reactor core blow-down. The present invention essentially comprises the use of flanged wire screens or similar devices, such as perforated plates, to produce certain desirable effects in the flow regime for monitoring purposes. One desirable effect is a measurable and reproducible pressure drop across the screen. The pressure drop can be characterized for various known flow rates and then used to monitor nonhomogeneous flow regimes. Another useful effect of the use of screens or plates in nonhomogeneous flow is that such apparatus tends to create a uniformly dispersed flow regime in the immediate downstream vicinity. This is a desirable effect because it usually increases the accuracy of flow rate measurements determined by conventional methods.

  3. Apparatus for monitoring two-phase flow

    International Nuclear Information System (INIS)

    Sheppard, J.D.; Tong, L.S.

    1977-01-01

    A method and apparatus for monitoring two-phase flow is provided that is particularly related to the monitoring of transient two-phase (liquid-vapor) flow rates such as may occur during a pressurized water reactor core blow-down. The present invention essentially comprises the use of flanged wire screens or similar devices, such as perforated plates, to produce certain desirable effects in the flow regime for monitoring purposes. One desirable effect is a measurable and reproducible pressure drop across the screen. The pressure drop can be characterized for various known flow rates and then used to monitor nonhomogeneous flow regimes. Another useful effect of the use of screens or plates in nonhomogeneous flow is that such apparatus tends to create a uniformly dispersed flow regime in the immediate downstream vicinity. This is a desirable effect because it usually increases the accuracy of flow rate measurements determined by conventional methods. 3 claims, 9 figures

  4. Designing and Constructing Blood Flow Monitoring System to Predict Pressure Ulcers on Heel

    Directory of Open Access Journals (Sweden)

    Akbari H.

    2014-06-01

    Full Text Available Background: A pressure ulcer is a complication related to the need for the care and treatment of primarily disabled and elderly people. With the decrease of the blood flow caused by the pressure loaded, ulcers are formed and the tissue will be wasted with the passage of time. Objective: The aim of this study was to construct blood flow monitoring system on the heel tissue which was under external pressure in order to evaluate the tissue treatment in the ulcer. Methods: To measure the blood flow changes, three infrared optical transmitters were used at the distances of 5, 10, and 15 mm to the receiver. Blood flow changes in heels were assessed in pressures 0, 30, and 60 mmHg. The time features were extracted for analysis from the recorded signal by MATLAB software. Changes of the time features under different pressures were evaluated at the three distances by ANOVA in SPSS software. The level of significance was considered at 0.05. Results: In this study, 15 subjects, including both male and female, with the mean age of 54±7 participated. The results showed that the signal amplitude, power and absolute signal decreased significantly when pressure on the tissue increased in different layers (p<0.05. Heart rate only decreased significantly in pressures more than 30 mmHg (p=0.02. In pressures more than 30 mmHg, in addition to a decrease in the time features, the pattern of blood flow signal changed and it wasn’t the same as noload signal. Conclusion: By detecting the time features, we can reach an early diagnosis to prognosticate the degeneration of the tissue under pressure and it can be recommended as a method to predict bedsores in the heel.

  5. Method and apparatus for monitoring two-phase flow. [PWR

    Science.gov (United States)

    Sheppard, J.D.; Tong, L.S.

    1975-12-19

    A method and apparatus for monitoring two-phase flow is provided that is particularly related to the monitoring of transient two-phase (liquid-vapor) flow rates such as may occur during a pressurized water reactor core blow-down. The present invention essentially comprises the use of flanged wire screens or similar devices, such as perforated plates, to produce certain desirable effects in the flow regime for monitoring purposes. One desirable effect is a measurable and reproducible pressure drop across the screen. The pressure drop can be characterized for various known flow rates and then used to monitor nonhomogeneous flow regimes. Another useful effect of the use of screens or plates in nonhomogeneous flow is that such apparatus tends to create a uniformly dispersed flow regime in the immediate downstream vicinity. This is a desirable effect because it usually increases the accuracy of flow rate measurements determined by conventional methods.

  6. Low parameter model to monitor bottom hole pressure in vertical multiphase flow in oil production wells

    Directory of Open Access Journals (Sweden)

    Mohammad Ali Ahmadi

    2016-09-01

    Full Text Available The importance of the flow patterns through petroleum production wells proved for upstream experts to provide robust production schemes based on the knowledge about flow behavior. To provide accurate flow pattern distribution through production wells, accurate prediction/representation of bottom hole pressure (BHP for determining pressure drop from bottom to surface play important and vital role. Nevertheless enormous efforts have been made to develop mechanistic approach, most of the mechanistic and conventional models or correlations unable to estimate or represent the BHP with high accuracy and low uncertainty. To defeat the mentioned hurdle and monitor BHP in vertical multiphase flow through petroleum production wells, inventive intelligent based solution like as least square support vector machine (LSSVM method was utilized. The evolved first-break approach is examined by applying precise real field data illustrated in open previous surveys. Thanks to the statistical criteria gained from the outcomes obtained from LSSVM approach, the proposed least support vector machine (LSSVM model has high integrity and performance. Moreover, very low relative deviation between the model estimations and the relevant actual BHP data is figured out to be less than 6%. The output gained from LSSVM model are closed the BHP while other mechanistic models fails to predict BHP through petroleum production wells. Provided solutions of this study explicated that implies of LSSVM in monitoring bottom-hole pressure can indicate more accurate monitoring of the referred target which can lead to robust design with high level of reliability for oil and gas production operation facilities.

  7. Surveillance of Hemodialysis Vascular Access with Ultrasound Vector Flow Imaging

    DEFF Research Database (Denmark)

    Brandt, Andreas Hjelm; Olesen, Jacob Bjerring; Lindskov Hansen, Kristoffer

    2015-01-01

    -functioning vascular access with as few complications as possible and preferred vascular access is an AVF. Dysfunction due to stenosis is a common complication, and regular monitoring of volume flow is recommended to preserve AVF patency. UDT is considered the gold standard for volume flow surveillance, but VFI has...... proven to be more precise, when performing single repeated instantaneous measurements. Three patients with AVF were monitored with UDT and VFI monthly for five months. A commercial ultrasound scanner with a 9 MHz linear array transducer with integrated VFI was used to obtain data. UDT values were...... be used for surveillance of volume flow....

  8. Organic electronics based pressure sensor towards intracranial pressure monitoring

    Science.gov (United States)

    Rai, Pratyush; Varadan, Vijay K.

    2010-04-01

    The intra-cranial space, which houses the brain, contains cerebrospinal fluid (CSF) that acts as a fluid suspension medium for the brain. The CSF is always in circulation, is secreted in the cranium and is drained out through ducts called epidural veins. The venous drainage system has inherent resistance to the flow. Pressure is developed inside the cranium, which is similar to a rigid compartment. Normally a pressure of 5-15 mm Hg, in excess of atmospheric pressure, is observed at different locations inside the cranium. Increase in Intra-Cranial Pressure (ICP) can be caused by change in CSF volume caused by cerebral tumors, meningitis, by edema of a head injury or diseases related to cerebral atrophy. Hence, efficient ways of monitoring ICP need to be developed. A sensor system and monitoring scheme has been discussed here. The system architecture consists of a membrane less piezoelectric pressure sensitive element, organic thin film transistor (OTFT) based signal transduction, and signal telemetry. The components were fabricated on flexible substrate and have been assembled using flip-chip packaging technology. Material science and fabrication processes, subjective to the device performance, have been discussed. Capability of the device in detecting pressure variation, within the ICP pressure range, is investigated and applicability of measurement scheme to medical conditions has been argued for. Also, applications of such a sensor-OTFT assembly for logic sensor switching and patient specific-secure monitoring system have been discussed.

  9. Automated electronic monitoring of circuit pressures during continuous renal replacement therapy: a technical report.

    Science.gov (United States)

    Zhang, Ling; Baldwin, Ian; Zhu, Guijun; Tanaka, Aiko; Bellomo, Rinaldo

    2015-03-01

    Automated electronic monitoring and analysis of circuit pressures during continuous renal replacement therapy (CRRT) has the potential to predict failure and allow intervention to optimise function. Current CRRT machines can measure and store pressure readings for downloading into databases and for analysis. We developed a procedure to obtain such data at intervals of 1 minute and analyse them using the Prismaflex CRRT machine, and we present an example of such analysis. We obtained data on pressures obtained at intervals of 1 minute in a patient with acute kidney injury and sepsis treated with continuous haemofiltration at 2 L/hour of ultrafiltration and a blood flow of 200 mL/minute. Data analysis identified progressive increases in transmembrane pressure (TMP) and prefilter pressure (PFP) from time 0 until 33 hours or clotting. TMP increased from 104 mmHg to 313 mmHg and PFP increased from from 131 mmHg to 185 mmHg. Effluent pressure showed a progressive increase in the negative pressure applied to achieve ultrafiltration from 0 mmHg to -168 mmHg. The inflection point for such changes was also identified. Blood pathway pressures for access and return remained unchanged throughout. Automated electronic monitoring of circuit pressure during CRRT is possible and provides useful information on the evolution of circuit clotting.

  10. Experimental research on pressure fluctuation and vibration in a mixed flow pump

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Kai; Liu, Houlin; Wang, Wenbo [National Research Center of Pumps and Pumping System Engineering and Technology, Jiangsu University, Zhenjiang (China); Zhou, Xiaohua [Gree Electric Appliance Inc. of Zhuhai, Zhuhai (China)

    2016-01-15

    To study the pressure fluctuation and vibration in mixed flow pumps, we chose a mixed flow pump with specific speed of 436.1 to measure. The time domains and frequency domain at each monitoring point on diffuser and outlet elbow were analyzed, as well as the vibration frequency domain characteristics at the impeller outlet and near the motor. The results show that the peak value of pressure fluctuation peak decreased gradually with the increase of flow rate. The pressure fluctuation of each monitoring point had periodicity, and the frequency domain dominated by blade passing frequency and multiple shaft frequency. The vibration frequency of each monitoring point occurred at shaft frequency and its multiple shaft frequency. The dominant frequency and the second frequency were distributed in shaft frequency and double shaft frequency.

  11. Design and Evaluation of a Pressure and Temperature Monitoring System for Pressure Ulcer Prevention

    Directory of Open Access Journals (Sweden)

    Farve Daneshvar Fard

    2014-08-01

    Full Text Available Introduction Pressure ulcers are tissue damages resulting from blood flow restriction, which occurs when the tissue is exposed to high pressure for a long period of time. These painful sores are common in patients and elderly, who spend extended periods of time in bed or wheelchair. In this study, a continuous pressure and temperature monitoring system was developed for pressure ulcer prevention. Materials and Methods The monitoring system consists of 64 pressure and 64 temperature sensors on a 40×50 cm2 sheet. Pressure and temperature data and the corresponding maps were displayed on a computer in real-time. Risk assessment could be performed by monitoring and recording absolute pressure and temperature values, as well as deviations over time. Furthermore, a posture detection procedure was proposed for sitting posture identification. Information about the patient’s movement history may help caregivers make informed decisions about the patient’s repositioning and ulcer prevention strategies. Results Steady temporal behaviour of the designed system and repeatability of the measurements were evaluated using several particular tests. The results illustrated that the system could be utilized for continuous monitoring of interface pressure and temperature for pressure ulcer prevention. Furthermore, the proposed method for detecting sitting posture was verified using a statistical analysis. Conclusion A continuous time pressure and temperature monitoring system was presented in this study. This system may be suited for pressure ulcer prevention given its feasibility for simultaneous monitoring of pressure and temperature and alarming options. Furthermore, a method for detecting different sitting postures was proposed and verified. Pressure ulcers in wheelchair-bound patients may be prevented using this sitting posture detection method.

  12. Non-Imaging Acoustical Properties in Monitoring Arteriovenous Hemodialysis Access. A Review

    Directory of Open Access Journals (Sweden)

    Anas Mohd Noor

    2015-12-01

    Full Text Available The limitations of the gold standard angiography technique in arteriovenous access surveillance have opened a gap for researchers to find the best way to monitor this condition with low-cost, non-invasive and continuous bedside monitoring. The phonoangiography technique has been developed prior to these limits. This measurement and monitoring technique, associated with intelligence signal processing, promises better analysis for early detection of hemodialysis access problems, such as stenosis and thrombosis. Some research groups have shown that the phonoangiography technique could identify as many as 20% of vascular diameter changes and also its frequency characteristics due to hemodialysis access problems. The frequency characteristics of these acoustical signals are presented and discussed in detail to understand the association with the stenosis level, blood flows, sensor locations, fundamental frequency bands of normal and abnormal conditions, and also the spectral energy produced. This promising technique could be used in the near future as a tool for pre-diagnosis of arteriovenous access before any further access correction by surgical techniques is required. This paper provides an extensive review of various arteriovenous access monitoring techniques based on non-imaging acoustical properties.

  13. Acoustic Emission for on-line reactor pressure boundary monitoring

    International Nuclear Information System (INIS)

    Hutton, P.H.; Kurtz, R.J.; Pappas, R.A.

    1985-01-01

    The program objective is to develop AE for continuous surveillance to assess flaw growth in reactor pressure boundaries. Technology in the laboratory is being evaluated on structures. Results have demonstrated basic feasibility of the program objective. AE monitoring a long term fatigue test of a pressure vessel demonstrated an instrument system, and the ability to detect unexpected as well as well as known fatigue cracks. Monitoring a nuclear reactor system shows that the coolant flow noise problem is manageable and AE can be detected under simulated operating conditions

  14. Making ambulatory blood pressure monitoring accessible in pharmacies.

    Science.gov (United States)

    James, Kirstyn; Dolan, Eamon; O'Brien, Eoin

    2014-06-01

    Ambulatory blood pressure measurement (ABPM), although recommended for the diagnosis and management of hypertension, has limited availability. The objective of this study was to show that if the characteristics of patients attending pharmacies for ABPM are similar to those attending primary care, the technique can be made more widely available to patients through pharmacies. A comparative study using a software program that allowed central collection, analysis and comparison of ABPM data from patients attending primary care and pharmacies for assessment of hypertension in Ireland. ABPM data from 46 978 patients attending primary care were compared with 1698 attending pharmacies between 2007 and 2013. The age, sex and blood pressure characteristics of patients attending primary care and pharmacies were similar. The mean pressures in all categories, except for systolic blood pressure recorded in primary care, were higher in men. The first ABPM measurements recorded in pharmacies were slightly higher than those in primary care (150.8 ± 19.5/88.7 ± 13.7 vs. 149.6 ± 20.7/88.0 ± 14.4 mmHg). More patients attending primary care were normotensive than those attending pharmacies (19.5 vs. 16.4%), whereas more patients attending pharmacies were hypertensive than those attending primary care (62.8 vs. 60.7%), particularly female patients (61.0 vs. 56.4%). White-coat hypertension was similar in patients attending primary care and pharmacies (19.8 vs. 20.8%), but it was more prevalent in men attending pharmacies (22.0 vs. 17.4%) and in women attending primary care (21.9 vs. 19.7%). There were more dippers in pharmacy then primary care ABPMs (84.7 vs. 79.4%). A preference for having ABPM on Fridays and Saturdays was evident in patients attending pharmacies (19.6 vs. 6.6%), whereas there was a preference for early morning recording in primary care (4.1 vs. 1.1%). This study, which is the first to report on ABPM data from the pharmacy setting, shows that the blood pressure

  15. Real-time display of flow-pressure-volume loops.

    Science.gov (United States)

    Morozoff, P E; Evans, R W

    1992-01-01

    Graphic display of respiratory waveforms can be valuable for monitoring the progress of ventilated patients. A system has been developed that can display flow-pressure-volume loops as derived from a patient's respiratory circuit in real time. It can also display, store, print, and retrieve ventilatory waveforms. Five loops can be displayed at once: current, previous, reference, "ideal," and previously saved. Two components, the data-display device (DDD) and the data-collection device (DCD), comprise the system. An IBM 286/386 computer with a graphics card (VGA) and bidirectional parallel port is used for the DDD; an eight-bit microprocessor card and an A/D convertor card make up the DCD. A real-time multitasking operating system was written to control the DDD, while the DCD operates from in-line assembly code. The DCD samples the pressure and flow sensors at 100 Hz and looks for a complete flow waveform pattern based on flow slope. These waveforms are then passed to the DDD via the mutual parallel port. Within the DDD a process integrates the flow to create a volume signal and performs a multilinear regression on the pressure, flow, and volume data to calculate the elastance, resistance, pressure offset, and coefficient of determination. Elastance, resistance, and offset are used to calculate Pr and Pc where: Pr[k] = P[k]-offset-(elastance.V[k]) and Pc[k] = P[k]-offset-(resistance.F[k]). Volume vs. Pc and flow vs. Pr can be displayed in real time. Patient data from previous clinical tests were loaded into the device to verify the software calculations. An analog waveform generator was used to simulate flow and pressure waveforms that validated the system.(ABSTRACT TRUNCATED AT 250 WORDS)

  16. Monitoring of deposits in pipelines using pressure pulse technology

    Energy Technology Data Exchange (ETDEWEB)

    Gudmundsson, Jon S.; Celius, Harald K.

    2005-07-01

    The basis of pressure pulse technology is presented in terms of the water hammer equation, the pipeline pressure drop equation and the equation for speed of sound in multiphase mixtures. The technology can be used for a range of applications, from on-line monitoring of flowing conditions to on-demand measurements and analysis to locate and quantify deposits in wells and pipelines. While pressure pulse measurements are low-cost and easy to implement, the commercial use of pressure pulse technology has resulted from extensive field experience and substantial in-house software development. Simulation tools were used to illustrate the effect of a 2 mm thick deposit, 500 m long and located 375 m from a quick-acting valve. The simulation conditions used are typical for multiphase gas-oil flow along a horizontal 2 km long pipeline from wellhead to manifold. (Author)

  17. Micromachined pressure/flow-sensor

    NARCIS (Netherlands)

    Oosterbroek, R.E.; Lammerink, Theodorus S.J.; Berenschot, Johan W.; Krijnen, Gijsbertus J.M.; Elwenspoek, Michael Curt; van den Berg, Albert

    1999-01-01

    The micromechanical equivalent of a differential pressure flow-sensor, well known in macro mechanics, is discussed. Two separate pressure sensors are used for the device, enabling to measure both, pressure as well as volume flow-rate. An integrated sensor with capacitive read-out as well as a

  18. High temperature, high pressure gas loop - the Component Flow Test Loop (CFTL)

    International Nuclear Information System (INIS)

    Gat, U.; Sanders, J.P.; Young, H.C.

    1984-01-01

    The high-pressure, high-temperature, gas-circulating Component Flow Test Loop located at Oak Ridge National Laboratory was designed and constructed utilizing Section III of the ASME Boiler and Pressure Vessel Code. The quality assurance program for operating and testing is also based on applicable ASME standards. Power to a total of 5 MW is available to the test section, and an air-cooled heat exchanger rated at 4.4 MW serves as heat sink. The three gas-bearing, completely enclosed gas circulators provide a maximum flow of 0.47 m 3 /s at pressures to 10.7 MPa. The control system allows for fast transients in pressure, power, temperature, and flow; it also supports prolonged unattended steady-state operation. The data acquisition system can access and process 10,000 data points per second. High-temperature gas-cooled reactor components are being tested

  19. Coronary diastolic pressure-flow relation and zero flow pressure explained on the basis of intramyocardial compliance

    NARCIS (Netherlands)

    Spaan, J. A.

    1985-01-01

    In the controversy about the mechanisms determining the high zero flow pressures and the further interpretation of coronary diastolic pressure flow relations, this paper takes a stand in favor of intramyocardial compliance as the primary cause of the high zero flow pressures. An attempt has been

  20. Reotemp Pressure Indicator - Local Pressure Indication to Monitor the SCHe Supply Bottle Pressure

    International Nuclear Information System (INIS)

    VAN KATWIJK, C.

    1999-01-01

    These 0-3000 psig range pressure indicators are located in the SCHe helium supply lines at the pressure bottles and upstream of the PRV. These accident monitoring local pressure indicators monitor the SCHe supply bottle pressure. There is one pressure indicator for each SCHe supply (4)

  1. Refrigeration. Two-Phase Flow. Flow Regimes and Pressure Drop

    DEFF Research Database (Denmark)

    Knudsen, Hans-Jørgen Høgaard

    2002-01-01

    The note gives the basic definitions used in two-phase flow. Flow regimes and flow regimes map are introduced. The different contributions to the pressure drop are stated together with an imperical correlation from the litterature.......The note gives the basic definitions used in two-phase flow. Flow regimes and flow regimes map are introduced. The different contributions to the pressure drop are stated together with an imperical correlation from the litterature....

  2. Open Access Monitor - DK

    DEFF Research Database (Denmark)

    Svendsen, Michael; Hansen, Lars Asger Juel; Andersen, Dorte

    2017-01-01

    Open Access Monitor - DK (OAM-DK) is a 2-year DEFF funded [DEFF.2016-0018] national project running in 2017-2018 with the aim of collecting, documenting and administrating Open Access publishing costs. OAM-DK is lead by Copenhagen University Library under the Royal Danish Library with participation...... of all Danish University Libraries. This poster presents the first results of Open Access costs related to 2015 publications at the The University of Copenhagen....

  3. Infinite-Dimensional Observer for Process Monitoring in Managed Pressure Drilling

    OpenAIRE

    Hasan, Agus Ismail

    2015-01-01

    Utilizing flow rate and pressure data in and out of the mud circulation loop provides a driller with real-time trends for the early detection of well-control problems that impact the drilling efficiency. This paper presents state estimation for infinite-dimensional systems used in the process monitoring of oil well drilling. The objective is to monitor the key process variables associated with process safety by designing a model-based nonlinear observer that directly utilizes the available in...

  4. The use of a low-cost gas-liquid flow meter to monitor severe slugging

    DEFF Research Database (Denmark)

    Andreussi, Paolo; Bonizzi, Marco; Ciandri, Paolo

    2017-01-01

    A very simple, low-cost gas-liquid flow meter that only employs conventional field instrumentation has been used to monitor severe slugging occurring at the exit of a vertical pipe. This meter was originally developed for conventional oil field applications [1] and is based on the readings...... method to monitor severe slugging by means of low cost instrumentation, in particular, by replacing a cumbersome instrument such as a gamma-densitometer with a differential pressure transmitter. In field operation, the multiphase orifice used in these experiments can be replaced by a calibrated control...... of a multiphase orifice and the pressure drops of the gas-liquid mixture flowing in a vertical section of the pipe. Liquid and gas flow rates have been determined by means of semi-empirical equations developed for the specific set of flow parameters (geometry, flow rates, physical properties) adopted in a series...

  5. Determinants of systemic zero-flow arterial pressure.

    Science.gov (United States)

    Brunner, M J; Greene, A S; Sagawa, K; Shoukas, A A

    1983-09-01

    Thirteen pentobarbital-anesthetized dogs whose carotid sinuses were isolated and perfused at a constant pressure were placed on total cardiac bypass. With systemic venous pressure held at 0 mmHg (condition 1), arterial inflow was stopped for 20 s at intrasinus pressures of 50, 125, and 200 mmHg. Zero-flow arterial pressures under condition 1 were 16.2 +/- 1.3 (SE), 13.8 +/- 1.1, and 12.5 +/- 0.8 mmHg, respectively. In condition 2, the venous outflow tube was clamped at the instant of stopping the inflow, causing venous pressure to rise. The zero-flow arterial pressures were 19.7 +/- 1.3, 18.5 +/- 1.4, and 16.4 +/- 1.2 mmHg for intrasinus pressures of 50, 125, and 200 mmHg, respectively. At all levels of intrasinus pressure, the zero-flow arterial pressure in condition 2 was higher (P less than 0.005) than in condition 1. In seven dogs, at an intrasinus pressure of 125 mmHg, epinephrine increased the zero-flow arterial pressure by 3.0 mmHg, whereas hexamethonium and papaverine decreased the zero-flow arterial pressure by 2 mmHg. Reductions in the hematocrit from 52 to 11% resulted in statistically significant changes (P less than 0.01) in zero-flow arterial pressures. Thus zero-flow arterial pressure was found to be affected by changes in venous pressure, hematocrit, and vasomotor tone. The evidence does not support the literally interpreted concept of the vascular waterfall as the model for the finite arteriovenous pressure difference at zero flow.

  6. Remote communications technology redefines integrity verification and monitoring of low pressure isolation

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2010-01-15

    In 2007, a ship collided with the southeast face of a satellite platform jacket in the North Sea, damaging the 12-inch export riser. Emergency shutdown valves immediately shut-in production from the platform, leaving the pressure in the pipeline at approximately 4 barg. The riser had to be repaired before production could resume. TDW Offshore Services (TDW) was hired to develop a low pressure solution to isolate the damaged section of the pipeline riser from the export pipeline gas inventory. TDW used its range of specialist pipeline pigging, pig tracking and remote communications technology to solve the problem. The solution consisted of a custom-designed TDW pig trap and pigging spread; a high friction pig train furnished with the SmartTrack remote tracking and pressure-monitoring system; a SmartTrack subsea remote tracking and pressure-monitoring system; a SmartTrack topside tracking and monitoring system with radio link to the dive support vessel; and a pipeline isolation ball valve. TDW was able to monitor the downstream pressure of each isolation pig continuously throughout the operation using its innovative technology that sends isolation integrity data by radio link to a dive support vessel through pipe wall communications. The use of remote tracking and pressure monitoring technology enabled TDW to make repairs to the damaged riser while maintaining a continuous flow throughout the duration of the operation. 4 figs.

  7. Sensor response monitoring in pressurized water reactors using time series modeling

    International Nuclear Information System (INIS)

    Upadhyaya, B.R.; Kerlin, T.W.

    1978-01-01

    Random data analysis in nuclear power reactors for purposes of process surveillance, pattern recognition and monitoring of temperature, pressure, flow and neutron sensors has gained increasing attention in view of their potential for helping to ensure safe plant operation. In this study, application of autoregressive moving-average (ARMA) time series modeling for monitoring temperature sensor response characteristrics is presented. The ARMA model is used to estimate the step and ramp response of the sensors and the related time constant and ramp delay time. The ARMA parameters are estimated by a two-stage algorithm in the spectral domain. Results of sensor testing for an operating pressurized water reactor are presented. 16 refs

  8. Marangoni flows induced by atmospheric-pressure plasma jets

    International Nuclear Information System (INIS)

    Berendsen, C W J; Van Veldhuizen, E M; Kroesen, G M W; Darhuber, A A

    2015-01-01

    We studied the interaction of atmospheric-pressure plasma jets of Ar or air with liquid films of an aliphatic hydrocarbon on moving solid substrates. The hydrodynamic jet-liquid interaction induces a track of lower film thickness. The chemical plasma-surface interaction oxidizes the liquid, leading to a local increase of the surface tension and a self-organized redistribution of the liquid film. We developed a numerical model that qualitatively reproduces the formation, instability and coarsening of the flow patterns observed in the experiments. Monitoring the liquid flow has potential as an in-situ, spatially and temporally resolved, diagnostic tool for the plasma-liquid surface interaction. (paper)

  9. Pressure fluctuation characteristics of flow field of mixed flow nuclear primary pump

    International Nuclear Information System (INIS)

    Wang Chunlin; Yang Xiaoyong; Li Changjun; Jia Fei; Zhao Binjuan

    2013-01-01

    In order to research the pressure fluctuation characteristics of flow field of mixed flow nuclear primary pump, this study used the technique of ANSYS-Workbench and CFX fluid solid heat coupling to do numerical simulation analysis for model pump. According to the situation of pressure fluctuation of time domain and frequency domain, the main cause of pressure fluctuation was discussed. For different flow, the pressure fluctuations were compared. This study shows it is feasible that large eddy simulation method is used for the research of pressure fluctuation. The pressure fluctuation amplitudes of four sections are increasing from wheel hub to wheel rim. The pressure fluctuation of inlet and outlet of impeller depends on the rotational frequency of impeller. Along with the fluid flowing away from the impeller, the effect of the impeller on the fluid pressure fluctuation weakens gradually. Comparing the different results of three flow conditions, the pressure fluctuation in design condition flow is superior to the others. (authors)

  10. Real-time combustion control and diagnostics sensor-pressure oscillation monitor

    Science.gov (United States)

    Chorpening, Benjamin T [Morgantown, WV; Thornton, Jimmy [Morgantown, WV; Huckaby, E David [Morgantown, WV; Richards, George A [Morgantown, WV

    2009-07-14

    An apparatus and method for monitoring and controlling the combustion process in a combustion system to determine the amplitude and/or frequencies of dynamic pressure oscillations during combustion. An electrode in communication with the combustion system senses hydrocarbon ions and/or electrons produced by the combustion process and calibration apparatus calibrates the relationship between the standard deviation of the current in the electrode and the amplitudes of the dynamic pressure oscillations by applying a substantially constant voltage between the electrode and ground resulting in a current in the electrode and by varying one or more of (1) the flow rate of the fuel, (2) the flow rate of the oxidant, (3) the equivalence ratio, (4) the acoustic tuning of the combustion system, and (5) the fuel distribution in the combustion chamber such that the amplitudes of the dynamic pressure oscillations in the combustion chamber are calculated as a function of the standard deviation of the electrode current. Thereafter, the supply of fuel and/or oxidant is varied to modify the dynamic pressure oscillations.

  11. Directly measuring spinal cord blood flow and spinal cord perfusion pressure via the collateral network: correlations with changes in systemic blood pressure.

    Science.gov (United States)

    Kise, Yuya; Kuniyoshi, Yukio; Inafuku, Hitoshi; Nagano, Takaaki; Hirayasu, Tsuneo; Yamashiro, Satoshi

    2015-01-01

    During thoracoabdominal surgery in which segmental arteries are sacrificed over a large area, blood supply routes from collateral networks have received attention as a means of avoiding spinal cord injury. The aim of this study was to investigate spinal cord blood supply through a collateral network by directly measuring spinal cord blood flow and spinal cord perfusion pressure experimentally. In beagle dogs (n = 8), the thoracoabdominal aorta and segmental arteries L1-L7 were exposed, and a temporary bypass was created for distal perfusion. Next, a laser blood flow meter was placed on the spinal dura mater in the L5 region to measure the spinal cord blood flow. The following were measured simultaneously when the direct blood supply from segmental arteries L2-L7 to the spinal cord was stopped: mean systemic blood pressure, spinal cord perfusion pressure (blood pressure within the aortic clamp site), and spinal cord blood flow supplied via the collateral network. These variables were then investigated for evidence of correlations. Positive correlations were observed between mean systemic blood pressure and spinal cord blood flow during interruption of segmental artery flow both with (r = 0.844, P flow with and without distal perfusion (r = 0.803, P network from outside the interrupted segmental arteries, and high systemic blood pressure (∼1.33-fold higher) was needed to obtain the preclamping spinal cord blood flow, whereas 1.68-fold higher systemic blood pressure was needed when distal perfusion was halted. Spinal cord blood flow is positively correlated with mean systemic blood pressure and spinal cord perfusion pressure under spinal cord ischemia caused by clamping a wide range of segmental arteries. In open and endovascular thoracic and thoracoabdominal surgery, elevating mean systemic blood pressure is a simple and effective means of increasing spinal cord blood flow, and measuring spinal cord perfusion pressure seems to be useful for monitoring

  12. Assessment and monitoring of flow limitation and other parameters from flow/volume loops.

    Science.gov (United States)

    Dueck, R

    2000-01-01

    Flow/volume (F/V) spirometry is routinely used for assessing the type and severity of lung disease. Forced vital capacity (FVC) and timed vital capacity (FEV1) provide the best estimates of airflow obstruction in patients with asthma, chronic obstructive pulmonary disease (COPD) and emphysema. Computerized spirometers are now available for early home recognition of asthma exacerbation in high risk patients with severe persistent disease, and for recognition of either infection or rejection in lung transplant patients. Patients with severe COPD may exhibit expiratory flow limitation (EFL) on tidal volume (VT) expiratory F/V (VTF/V) curves, either with or without applying negative expiratory pressure (NEP). EFL results in dynamic hyperinflation and persistently raised alveolar pressure or intrinsic PEEP (PEEPi). Hyperinflation and raised PEEPi greatly enhance dyspnea with exertion through the added work of the threshold load needed to overcome raised pleural pressure. Esophageal (pleural) pressure monitoring may be added to VTF/V loops for assessing the severity of PEEPi: 1) to optimize assisted ventilation by mask or via endotracheal tube with high inspiratory flow rates to lower I:E ratio, and 2) to assess the efficacy of either pressure support ventilation (PSV) or low level extrinsic PEEP in reducing the threshold load of PEEPi. Intraoperative tidal volume F/V loops can also be used to document the efficacy of emphysema lung volume reduction surgery (LVRS) via disappearance of EFL. Finally, the mechanism of ventilatory constraint can be identified with the use of exercise tidal volume F/V loops referenced to maximum F/V loops and static lung volumes. Patients with severe COPD show inspiratory F/V loops approaching 95% of total lung capacity, and flow limitation over the entire expiratory F/V curve during light levels of exercise. Surprisingly, patients with a history of congestive heart failure may lower lung volume towards residual volume during exercise

  13. Pressure sensitivity of flow oscillations in postocclusive reactive skin hyperemia.

    Science.gov (United States)

    Strucl, M; Peterec, D; Finderle, Z; Maver, J

    1994-05-01

    Skin blood flow was monitored using a laser-Doppler (LD) flowmeter in 21 healthy volunteers after an occlusion of the digital arteries. The peripheral vascular bed was exposed to occlusion ischemia of varying duration (1, 4, or 8 min) and to a change in digital arterial pressure produced by different positions of the arm above heart level to characterize the pattern of LD flow oscillations in postocclusive reactive hyperemia (PRH) and to elucidate the relevance of metabolic and myogenic mechanisms in governing its fundamental frequency. The descending part of the hyperemic flow was characterized by the appearance of conspicuous periodic oscillations with a mean fundamental frequency of 7.2 +/- 1.5 cycles/min (SD, n = 9), as assessed by a Fourier transform frequency analysis of 50-s sections of flow. The mean respiratory frequency during the periods of flow frequency analysis was 17.0 +/- 2.2 (SD, n = 9), and the PRH oscillations remained during apnea in all tested subjects. The area under the maximum flow curve increased significantly with prolongation of the occlusion (paired t test, P blood pressure in the digital arteries, which suggests the predominant role of a metabolic component in this part of the PRH response. In contrast, the fundamental frequency of PRH oscillations exhibited a significant decrease with a reduction in the estimated digital arterial pressure (linear regression, b = 0.08, P < 0.001; n = 12), but did not change with the prolongation of arterial occlusion despite a significant increase in mean LD flow (paired t test, P < 0.001; n = 9).(ABSTRACT TRUNCATED AT 250 WORDS)

  14. Microoptomechanical sensor for intracranial pressure monitoring

    International Nuclear Information System (INIS)

    Andreeva, A V; Luchinin, V V; Lutetskiy, N A; Sergushichev, A N

    2014-01-01

    The main idea of this research is the development of microoptomechanical sensor for intracranial pressure monitoring. Currently, the authors studied the scientific and technical knowledge in this field, as well as develop and test a prototype of microoptomechanical sensor for intracranial pressure (ICP) monitoring

  15. Continuous stroke volume monitoring by modelling flow from non-invasive measurement of arterial pressure in humans under orthostatic stress

    NARCIS (Netherlands)

    Harms, M.P.M.; Wesseling, K.H.; Pott, F.; Jenstrup, M.; Goudoever, J. van; Secher, N.H.; Lieshout, J.J. van

    1999-01-01

    The relationship between aortic flow and pressure is described by a three-element model of the arterial input impedance, including continuous correction for variations in the diameter and the compliance of the aorta (Modelflow). We computed the aortic flow from arterial pressure by this model, and

  16. Miniature Flow-Direction/Pitot-Static Pressure Probes

    Science.gov (United States)

    Ashby, George C., Jr.; Coombs, David S.; Eves, John W.; Price, Howard E.; Vasquez, Peter

    1989-01-01

    Precision flow-direction/pitot-static pressure probes, ranging from 0.035 to 0.090 inch (0.89 to 2.29 mm) in outside diameter, successfully fabricated and calibrated for use in Langley 20-inch Mach 6 Tunnel. Probes simultaneously measure flow direction and static and pitot pressures in flow fields about configurations in hypersonic flow at temperatures up to 500 degree F (260 degree C).

  17. Continuous cuff-less blood pressure monitoring based on the pulse arrival time approach: the impact of posture.

    Science.gov (United States)

    Muehlsteff, J; Aubert, X A; Morren, G

    2008-01-01

    There is an unmet need for cuff-less blood pressure (BP) monitoring especially, in personal healthcare applications. The pulse arrival time (PAT) approach might offer a suitable solution to enable comfortable BP monitoring even at beat-level. However, the methodology is based on hemodynamic surrogate measures, which are sensitive to patient activities such as posture changes, not necessarily related to blood pressure variations. In this paper, we analyze the impact of posture on the PAT measure and related hemodynamic parameters such as the pre-ejection period in well-defined procedures. Additionally, the PAT of a monitored subject is investigated in an unsupervised scenario illustrating the complexity of such a measurement. Our results show the failure of blood pressure inference based on simple calibration strategies using the PAT measure only. We discuss opportunities to compensate for the observed effects towards the realization of wearable cuff-less blood pressure monitoring. These findings emphasize the importance of accessing context information in personal healthcare applications, where vital sign monitoring is typically unsupervised.

  18. Blood pressure monitors for home

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/007482.htm Blood pressure monitors for home To use the sharing features ... may ask you to keep track of your blood pressure at home. To do this, you will need ...

  19. Monitoring Accessibility Services in Digital Television

    Directory of Open Access Journals (Sweden)

    Francisco Utray

    2012-01-01

    Full Text Available This paper addresses methodology and tools applied to the monitoring of accessibility services in digital television at a time when the principles of accessibility and design are being considered in all new audiovisual media communication services. The main objective of this research is to measure the quality and quantity of existing accessibility services offered by digital terrestrial television (DTT. The preliminary results, presented here, offer the development of a prototype for automatic monitoring and a methodology for obtaining quality measurements, along with the conclusions drawn by initial studies carried out in Spain. The recent approval of the UN Convention on the Rights of Persons with Disabilities gives special relevance to this research because it provides valuable guidelines to help set the priorities to improve services currently available to users.

  20. Two-phase flow boiling pressure drop in small channels

    International Nuclear Information System (INIS)

    Sardeshpande, Madhavi V.; Shastri, Parikshit; Ranade, Vivek V.

    2016-01-01

    Highlights: • Study of typical 19 mm steam generator tube has been undertaken in detail. • Study of two phase flow boiling pressure drop, flow instability and identification of flow regimes using pressure fluctuations is the main focus of present work. • Effect of heat and mass flux on pressure drop and void fraction was studied. • Flow regimes identified from pressure fluctuations data using FFT plots. • Homogeneous model predicted pressure drop well in agreement. - Abstract: Two-phase flow boiling in small channels finds a variety of applications in power and process industries. Heat transfer, boiling flow regimes, flow instabilities, pressure drop and dry out are some of the key issues related to two-phase flow boiling in channels. In this work, the focus is on pressure drop in two-phase flow boiling in tubes of 19 mm diameter. These tubes are typically used in steam generators. Relatively limited experimental database is available on 19 mm ID tube. Therefore, in the present work, the experimental set-up is designed for studying flow boiling in 19 mm ID tube in such a way that any of the different flow regimes occurring in a steam generator tube (from pre-heating of sub-cooled water to dry-out) can be investigated by varying inlet conditions. The reported results cover a reasonable range of heat and mass flux conditions such as 9–27 kW/m 2 and 2.9–5.9 kg/m 2 s respectively. In this paper, various existing correlations are assessed against experimental data for the pressure drop in a single, vertical channel during flow boiling of water at near-atmospheric pressure. A special feature of these experiments is that time-dependent pressures are measured at four locations along the channel. The steady-state pressure drop is estimated and the identification of boiling flow regimes is done with transient characteristics using time series analysis. Experimental data and corresponding results are compared with the reported correlations. The results will be

  1. Measuring sub-bandage pressure: comparing the use of pressure monitors and pulse oximeters.

    Science.gov (United States)

    Satpathy, A; Hayes, S; Dodds, S R

    2006-03-01

    To test the use of low-cost sub-bandage pressure monitors and pulse oximeters as part of a quality-control measure for graduated compression bandaging in leg ulcer clinics. Twenty-five healthy volunteers (mean age 40 years) providing 50 limbs were bandaged with a four-layer compression bandaging system. The ankle systolic pressure (ASP) was measured using a pulse oximeter (Nellcor NBP-40) before applying the graduated compression bandages. Interface pressure was measured by placing pressure sensors on the skin at three points (2cm above the medial malleolus; the widest part of the calf; and a point midway between them) in the supine and standing positions. The ASP was measured again with the pulse oximeter after the bandage had been applied, and the effect of the bandage on the ASP was recorded. The actual pressure created by the bandage was compared with the required pressure profile. Interface pressures varied with change of position and movement. With the operator blinded to the pressure monitors while applying the bandages, the target pressure of 35-40mmHg at the ankle was achieved in only 36% of limbs ([mean +/- 95% confidence interval]; 32.3 +/- 1.6mmHg [supine]; 38.4 +/- 2.4mmHg [standing position]). With the help of the pressure monitors, the target pressure was achieved in 78% of the limbs. There was no correlation between the pressure monitors and pulse oximeter pressures, demonstrating that the pulse oximeter is not a useful tool for measuring sub-bandage pressures. The results suggest a tool (interface pressure monitors) that is easy to operate should be available as part of quality assurance for treatment, training of care providers and education.

  2. Improving ecological response monitoring of environmental flows.

    Science.gov (United States)

    King, Alison J; Gawne, Ben; Beesley, Leah; Koehn, John D; Nielsen, Daryl L; Price, Amina

    2015-05-01

    Environmental flows are now an important restoration technique in flow-degraded rivers, and with the increasing public scrutiny of their effectiveness and value, the importance of undertaking scientifically robust monitoring is now even more critical. Many existing environmental flow monitoring programs have poorly defined objectives, nonjustified indicator choices, weak experimental designs, poor statistical strength, and often focus on outcomes from a single event. These negative attributes make them difficult to learn from. We provide practical recommendations that aim to improve the performance, scientific robustness, and defensibility of environmental flow monitoring programs. We draw on the literature and knowledge gained from working with stakeholders and managers to design, implement, and monitor a range of environmental flow types. We recommend that (1) environmental flow monitoring programs should be implemented within an adaptive management framework; (2) objectives of environmental flow programs should be well defined, attainable, and based on an agreed conceptual understanding of the system; (3) program and intervention targets should be attainable, measurable, and inform program objectives; (4) intervention monitoring programs should improve our understanding of flow-ecological responses and related conceptual models; (5) indicator selection should be based on conceptual models, objectives, and prioritization approaches; (6) appropriate monitoring designs and statistical tools should be used to measure and determine ecological response; (7) responses should be measured within timeframes that are relevant to the indicator(s); (8) watering events should be treated as replicates of a larger experiment; (9) environmental flow outcomes should be reported using a standard suite of metadata. Incorporating these attributes into future monitoring programs should ensure their outcomes are transferable and measured with high scientific credibility.

  3. Improving Ecological Response Monitoring of Environmental Flows

    Science.gov (United States)

    King, Alison J.; Gawne, Ben; Beesley, Leah; Koehn, John D.; Nielsen, Daryl L.; Price, Amina

    2015-05-01

    Environmental flows are now an important restoration technique in flow-degraded rivers, and with the increasing public scrutiny of their effectiveness and value, the importance of undertaking scientifically robust monitoring is now even more critical. Many existing environmental flow monitoring programs have poorly defined objectives, nonjustified indicator choices, weak experimental designs, poor statistical strength, and often focus on outcomes from a single event. These negative attributes make them difficult to learn from. We provide practical recommendations that aim to improve the performance, scientific robustness, and defensibility of environmental flow monitoring programs. We draw on the literature and knowledge gained from working with stakeholders and managers to design, implement, and monitor a range of environmental flow types. We recommend that (1) environmental flow monitoring programs should be implemented within an adaptive management framework; (2) objectives of environmental flow programs should be well defined, attainable, and based on an agreed conceptual understanding of the system; (3) program and intervention targets should be attainable, measurable, and inform program objectives; (4) intervention monitoring programs should improve our understanding of flow-ecological responses and related conceptual models; (5) indicator selection should be based on conceptual models, objectives, and prioritization approaches; (6) appropriate monitoring designs and statistical tools should be used to measure and determine ecological response; (7) responses should be measured within timeframes that are relevant to the indicator(s); (8) watering events should be treated as replicates of a larger experiment; (9) environmental flow outcomes should be reported using a standard suite of metadata. Incorporating these attributes into future monitoring programs should ensure their outcomes are transferable and measured with high scientific credibility.

  4. Calibration measurements using the ORNL fissile mass flow monitor

    International Nuclear Information System (INIS)

    March-Leuba, J.; Uckan, T.; Sumner, J.; Mattingly, J.; Mihalczo, J.

    1998-01-01

    This paper presents a demonstration of fissile-mass-flow measurements using the Oak Ridge National Laboratory (ORNL) Fissile Mass Flow Monitor in the Paducah Gaseous Diffusion Plant (PGDP). This Flow Monitor is part of a Blend Down Monitoring System (BDMS) that will be installed in at least two Russian Federation (R.F.) blending facilities. The key objectives of the demonstration of the ORNL Flow Monitor are two: (a) demonstrate that the ORNL Flow Monitor equipment is capable of reliably monitoring the mass flow rate of 235 UF 6 gas, and (b) provide a demonstration of ORNL Flow Monitor system in operation with UF 6 flow for a visiting R.F. delegation. These two objectives have been met by the PGDP demonstration, as presented in this paper

  5. Intracranial Pressure Monitoring

    DEFF Research Database (Denmark)

    Raboel, P H; Bartek, J; Andresen, M

    2012-01-01

    Monitoring of intracranial pressure (ICP) has been used for decades in the fields of neurosurgery and neurology. There are multiple techniques: invasive as well as noninvasive. This paper aims to provide an overview of the advantages and disadvantages of the most common and well-known methods...

  6. High-pressure plastic scintillation detector for measuring radiogenic gases in flow systems

    Science.gov (United States)

    Schell, W. R.; Vives-Batlle, J.; Yoon, S. R.; Tobin, M. J.

    1999-02-01

    Radioactive gases are emitted into the atmosphere from nuclear electric power and nuclear fuel reprocessing plants, from hospitals discarding xenon used in diagnostic medicine, as well as from nuclear weapons tests. A high-pressure plastic scintillation detector was constructed to measure atmospheric levels of such radioactive gases by detecting the beta and internal conversion (IC) electron decays. Operational tests and calibrations were made that permit integration of the flow detectors into a portable Gas Analysis, Separation and Purification system (GASP). The equipment developed can be used for measuring fission gases released from nuclear reactor sources and/or as part of monitoring equipment for enforcing the Comprehensive Test Ban Treaty. The detector is being used routinely for in-line gas separation efficiency measurements, at the elevated operational pressures used for the high-pressure swing analysis system (2070 kPa) and at flow rates of 5-15 l/min [1, 2]. This paper presents the design features, operational methods, calibration, and detector applications.

  7. High-pressure plastic scintillation detector for measuring radiogenic gases in flow systems

    International Nuclear Information System (INIS)

    Schell, W.R.; Vives-Batlle, J.; Yoon, S.R; Tobin, M.J.

    1999-01-01

    Radioactive gases are emitted into the atmosphere from nuclear electric power and nuclear fuel reprocessing plants, from hospitals discarding xenon used in diagnostic medicine, as well as from nuclear weapons tests. A high-pressure plastic scintillation detector was constructed to measure atmospheric levels of such radioactive gases by detecting the beta and internal conversion (IC) electron decays. Operational tests and calibrations were made that permit integration of the flow detectors into a portable Gas Analysis, Separation and Purification system (GASP). The equipment developed can be used for measuring fission gases released from nuclear reactor sources and/or as part of monitoring equipment for enforcing the Comprehensive Test Ban Treaty. The detector is being used routinely for in-line gas separation efficiency measurements, at the elevated operational pressures used for the high-pressure swing analysis system (2070 kPa) and at flow rates of 5-15 l/min . This paper presents the design features, operational methods, calibration, and detector applications

  8. High-pressure plastic scintillation detector for measuring radiogenic gases in flow systems

    CERN Document Server

    Schell, W R; Yoon, S R; Tobin, M J

    1999-01-01

    Radioactive gases are emitted into the atmosphere from nuclear electric power and nuclear fuel reprocessing plants, from hospitals discarding xenon used in diagnostic medicine, as well as from nuclear weapons tests. A high-pressure plastic scintillation detector was constructed to measure atmospheric levels of such radioactive gases by detecting the beta and internal conversion (IC) electron decays. Operational tests and calibrations were made that permit integration of the flow detectors into a portable Gas Analysis, Separation and Purification system (GASP). The equipment developed can be used for measuring fission gases released from nuclear reactor sources and/or as part of monitoring equipment for enforcing the Comprehensive Test Ban Treaty. The detector is being used routinely for in-line gas separation efficiency measurements, at the elevated operational pressures used for the high-pressure swing analysis system (2070 kPa) and at flow rates of 5-15 l/min . This paper presents the design features, opera...

  9. Side effects of ambulatory blood pressure monitoring.

    NARCIS (Netherlands)

    Steen, M.S. van der; Lenders, J.W.M.; Thien, Th.

    2005-01-01

    OBJECTIVE: To study the experiences and complaints of patients who underwent 24 h blood pressure monitoring. METHODS: Two groups of hypertensive patients of a tertiary outpatient clinic were asked to fill in a nine-item questionnaire about the side effects of ambulatory blood pressure monitoring

  10. Ambulatory Blood Pressure Monitoring in Clinical Practice: A Review

    Science.gov (United States)

    Viera, Anthony J.; Shimbo, Daichi

    2016-01-01

    Ambulatory blood pressure monitoring offers the ability to collect blood pressure readings several times an hour across a 24-hour period. Ambulatory blood pressure monitoring facilitates the identification of white-coat hypertension, the phenomenon whereby certain individuals who are not on antihypertensive medication show elevated blood pressure in a clinical setting but show non-elevated blood pressure averages when assessed by ambulatory blood pressure monitoring. Additionally, readings can be segmented into time windows of particular interest, e.g., mean daytime and nighttime values. During sleep, blood pressure typically decreases, or dips, such that mean sleep blood pressure is lower than mean awake blood pressure. A non-dipping pattern and nocturnal hypertension are strongly associated with increased cardiovascular morbidity and mortality. Approximately 70% of individuals dip ≥10% at night, while 30% have non-dipping patterns, when blood pressure remains similar to daytime average, or occasionally rises above daytime average. The various blood pressure categorizations afforded by ambulatory blood pressure monitoring are valuable for clinical management of high blood pressure since they increase accuracy for diagnosis and the prediction of cardiovascular risk. PMID:25107387

  11. Access control mechanism of wireless gateway based on open flow

    Science.gov (United States)

    Peng, Rong; Ding, Lei

    2017-08-01

    In order to realize the access control of wireless gateway and improve the access control of wireless gateway devices, an access control mechanism of SDN architecture which is based on Open vSwitch is proposed. The mechanism utilizes the features of the controller--centralized control and programmable. Controller send access control flow table based on the business logic. Open vSwitch helps achieve a specific access control strategy based on the flow table.

  12. Aschroft Pressure Switch - Monitor for Low SCHe Supply Bottle Pressure

    International Nuclear Information System (INIS)

    VAN KATWIJK, C.

    2000-01-01

    These pressure switches are located in the SCHe helium supply lines at the pressure bottles and upstream of the PRV. The switches monitor the SCHe supply bottle pressure and are set to alarm at 2200 psig. There is one switch for each SCHe supply (4). Electronic output signal is NON-SAFETY (GS)

  13. Title: variations and sensitivities of some blood pressure monitors ...

    African Journals Online (AJOL)

    Blood pressure is the pressure exerted by circulating blood upon the walls of blood vessels. Accuracy in blood pressure meters is of essence to health, especially in blood pressure monitoring and treatment. The aim of this research was to compare the readings and the sensitivities of some blood pressure monitors in use ...

  14. Practical utility of on-line clearance and blood temperature monitors as noninvasive techniques to measure hemodialysis blood access flow.

    Science.gov (United States)

    Fontseré, Néstor; Blasco, Miquel; Maduell, Francisco; Vera, Manel; Arias-Guillen, Marta; Herranz, Sandra; Blanco, Teresa; Barrufet, Marta; Burrel, Marta; Montaña, Javier; Real, Maria Isabel; Mestres, Gaspar; Riambau, Vicenç; Campistol, Josep M

    2011-01-01

    Access blood flow (Qa) measurements are recommended by the current guidelines as one of the most important components in vascular access maintenance programs. This study evaluates the efficiency of Qa measurement with on-line conductivity (OLC-Qa) and blood temperature monitoring (BTM-Qa) in comparison with the gold standard saline dilution method (SDM-Qa). 50 long-term hemodialysis patients (42 arteriovenous fistulas/8 arteriovenous grafts) were studied. Bland-Altman and Lin's coefficient (ρ(c)) were used to study accuracy and precision. Mean values were 1,021.7 ± 502.4 ml/min SDM-Qa, 832.8 ± 574.3 ml/min OLC-Qa (p = 0.007) and 1,094.9 ± 491.9 ml/min with BTM-Qa (p = NS). Biases and ρ(c) obtained were -188.8 ml/min (ρ(c) 0.58) OLC-Qa and 73.2 ml/min (ρ(c) 0.89) BTM-Qa. The limits of agreement (bias ± 1.96 SD) obtained were from -1,119 to 741.3 ml/min (OLC-Qa) and -350.6 to 497.2 ml/min (BTM-Qa). BTM-Qa and OLC-Qa are valid noninvasive and practical methods to estimate Qa, although BTM-Qa was more accurate and had better concordance than OLC-Qa compared with SDM-Qa. Copyright © 2010 S. Karger AG, Basel.

  15. Continuous Blood Pressure Monitoring in Daily Life

    Science.gov (United States)

    Lopez, Guillaume; Shuzo, Masaki; Ushida, Hiroyuki; Hidaka, Keita; Yanagimoto, Shintaro; Imai, Yasushi; Kosaka, Akio; Delaunay, Jean-Jacques; Yamada, Ichiro

    Continuous monitoring of blood pressure in daily life could improve early detection of cardiovascular disorders, as well as promoting healthcare. Conventional ambulatory blood pressure monitoring (ABPM) equipment can measure blood pressure at regular intervals for 24 hours, but is limited by long measuring time, low sampling rate, and constrained measuring posture. In this paper, we demonstrate a new method for continuous real-time measurement of blood pressure during daily activities. Our method is based on blood pressure estimation from pulse wave velocity (PWV) calculation, which formula we improved to take into account changes in the inner diameter of blood vessels. Blood pressure estimation results using our new method showed a greater precision of measured data during exercise, and a better accuracy than the conventional PWV method.

  16. Diastolic coronary artery pressure-flow velocity relationships in conscious man.

    Science.gov (United States)

    Dole, W P; Richards, K L; Hartley, C J; Alexander, G M; Campbell, A B; Bishop, V S

    1984-09-01

    We characterised the diastolic pressure-flow velocity relationship in the normal left coronary artery of conscious man before and after vasodilatation with angiographic contrast medium. Phasic coronary artery pressure and flow velocity were measured in ten patients during individual diastoles (0.5 to 1.0 s) using a 20 MHz catheter-tipped, pulsed Doppler transducer. All pressure-flow velocity curves were linear over the diastolic pressure range of 110 +/- 15 (SD) mmHg to 71 +/- 7 mmHg (r = 0.97 +/- 0.01). In the basal state, values for slope and extrapolated zero flow pressure intercept averaged 0.35 +/- 0.12 cm X s-1 X mmHg-1 and 51.7 +/- 8.6 mmHg, respectively. Vasodilatation resulted in a 2.5 +/- 0.5 fold increase in mean flow velocity. The diastolic pressure-flow velocity relationship obtained during peak vasodilatation compared to that during basal conditions was characterised by a steeper slope (0.80 +/- 0.48 cm X s-1 X mmHg-1, p less than 0.001) and lower extrapolated zero flow pressure intercept (37.9 +/- 9.8 mmHg, p less than 0.05). Mean right atrial pressure for the group averaged 4.4 +/- 1.7 mmHg, while left ventricular end-diastolic pressure averaged 8.7 +/- 2.8 mmHg. These observations in man are similar to data reported in the canine coronary circulation which are consistent with a vascular waterfall model of diastolic flow regulation. In this model, coronary blood flow may be regulated by changes in diastolic zero flow pressure as well as in coronary resistance.

  17. Pressurized water reactor flow arrangement

    International Nuclear Information System (INIS)

    Gibbons, J.F.; Knapp, R.W.

    1980-01-01

    A flow path is provided for cooling the control rods of a pressurized water reactor. According to this scheme, a small amount of cooling water enters the control rod guide tubes from the top and passes downwards through the tubes before rejoining the main coolant flow and passing through the reactor core. (LL)

  18. High-pressure plastic scintillation detector for measuring radiogenic gases in flow systems

    International Nuclear Information System (INIS)

    Schell, W.R.; Tobin, M.J.; Vives-Batlle, J.; Yoon, S.R.

    1999-01-01

    Radioactive gases are emitted into the atmosphere from nuclear electric power and nuclear fuel reprocessing plants, from hospitals discarding xenon used in diagnostic medicine, as well as from nuclear weapons tests. A high-pressure plastic scintillation detector was constructed to measure atmospheric levels of such radioactive gases by detecting the beta and internal conversion (IC) electron decays. Operational tests and calibrations were made that permit integration of the flow detectors into a portable Gas Analysis, Separation and Purification system (GASP). The equipment developed can be used for measuring fission gases released from nuclear reactor sources and/or as part of monitoring equipment for enforcing the Comprehensive Test Ban Treaty. The detector is being used routinely for in-line gas separation efficiency measurements, at the elevated operational pressures used for the high-pressure swing analysis system (2070 kPa) and at flow rates of 5-15 l/min. This paper presents the design features, operational methods, calibration, and detector applications. (Copyright (c) 1999 Elsevier Science B.V., Amsterdam. All rights reserved.)

  19. Measuring and monitoring energy access: Decision-support tools for policymakers in Africa

    International Nuclear Information System (INIS)

    Hailu, Yohannes G.

    2012-01-01

    A significant number of African States have adapted energy access targets. In evaluating progress towards these goals, measuring and monitoring energy access becomes relevant. This paper reviews energy access indicators and identifies their utility and challenges in their application. By focusing on Africa, a broader framework for energy access measurement and monitoring is discussed, along with implementation barriers and potential solutions. To demonstrate the utility of energy access decision-support tool in Africa, a scenario analysis in five regional energy pools is conducted using the Energy Spending Model tool. Institutionalizing monitoring and decision-support tools can provide valuable feedback to policymakers aiming to design and implement effective energy access programs serving a growing population in Africa. - Highlights: ► Most African countries have adapted energy access targets. ► To monitor and evaluate performance, monitoring and decision-support tools are required. ► Framework for tool development should consider data, cost, political and other factors. ► Implementation constraints include technical, data, resource and urban/rural issues. ► Electricity Spending Needs model is one decision support tool that ties access targets to investment needs. ► Monitoring tools provide crucial feedback on Africa's energy access progress.

  20. Information-flow-based Access Control for Virtualized Systems

    Directory of Open Access Journals (Sweden)

    Dmitriy Aleksandrovich Postoev

    2014-12-01

    Full Text Available The article is devoted to the method of information-flow-based access control, adopted for virtualized systems. General structure of access control system for virtual infrastructure is proposed.

  1. Pressure sensor to determine spatial pressure distributions on boundary layer flows

    Science.gov (United States)

    Sciammarella, Cesar A.; Piroozan, Parham; Corke, Thomas C.

    1997-03-01

    The determination of pressures along the surface of a wind tunnel proves difficult with methods that must introduce devices into the flow stream. This paper presents a sensor that is part of the wall. A special interferometric reflection moire technique is developed and used to produce signals that measures pressure both in static and dynamic settings. The sensor developed is an intelligent sensor that combines optics and electronics to analyze the pressure patterns. The sensor provides the input to a control system that is capable of modifying the shape of the wall and preserve the stability of the flow.

  2. Monitoring probe for groundwater flow

    Science.gov (United States)

    Looney, B.B.; Ballard, S.

    1994-08-23

    A monitoring probe for detecting groundwater migration is disclosed. The monitor features a cylinder made of a permeable membrane carrying an array of electrical conductivity sensors on its outer surface. The cylinder is filled with a fluid that has a conductivity different than the groundwater. The probe is placed in the ground at an area of interest to be monitored. The fluid, typically saltwater, diffuses through the permeable membrane into the groundwater. The flow of groundwater passing around the permeable membrane walls of the cylinder carries the conductive fluid in the same general direction and distorts the conductivity field measured by the sensors. The degree of distortion from top to bottom and around the probe is precisely related to the vertical and horizontal flow rates, respectively. The electrical conductivities measured by the sensors about the outer surface of the probe are analyzed to determine the rate and direction of the groundwater flow. 4 figs.

  3. Flow Control Device Evaluation for an Internal Flow with an Adverse Pressure Gradient

    Science.gov (United States)

    Jenkins, Luther N.; Gorton, Susan Althoff; Anders, Scott G.

    2002-01-01

    The effectiveness of several active and passive devices to control flow in an adverse pressure gradient with secondary flows present was evaluated in the 15 Inch Low Speed Tunnel at NASA Langley Research Center. In this study, passive micro vortex generators, micro bumps, and piezoelectric synthetic jets were evaluated for their flow control characteristics using surface static pressures, flow visualization, and 3D Stereo Digital Particle Image Velocimetry. Data also were acquired for synthetic jet actuators in a zero flow environment. It was found that the micro vortex generator is very effective in controlling the flow environment for an adverse pressure gradient, even in the presence of secondary vortical flow. The mechanism by which the control is effected is a re-energization of the boundary layer through flow mixing. The piezoelectric synthetic jet actuators must have sufficient velocity output to produce strong longitudinal vortices if they are to be effective for flow control. The output of these devices in a laboratory or zero flow environment will be different than the output in a flow environment. In this investigation, the output was higher in the flow environment, but the stroke cycle in the flow did not indicate a positive inflow into the synthetic jet.

  4. Model-based monitoring techniques for leakage localization in distribution water networks

    OpenAIRE

    Meseguer Amela, Jordi; Mirats Tur, Josep Maria; Cembrano Gennari, Gabriela; Puig Cayuela, Vicenç

    2015-01-01

    This is an open access article under the CC BY-NC-ND license This paper describes an integrated model-based monitoring framework for leakage localization in district-metered areas (DMA) of water distribution networks, which takes advantage of the availability of a hydraulic model of the network. The leakage localization methodology is based on the use of flow and pressure sensors at the DMA inlets and a limited number of pressure sensors deployed inside the DMA. The placement of these sens...

  5. Experimental Investigation of Pressure Drop and Pressure Distribution Along a Heated Channel in Subcooled Flow Boiling

    International Nuclear Information System (INIS)

    Aharon, Y.; Hochbaum, I.; Shai, I.

    2002-01-01

    The state of knowledge relating to pressure drop in subcooled boiling region is very unsatisfactory. That pressure drop is an important factor in considering the design of nuclear reactors because of the possibility of flow excursion during a two phase flow in the channels. In operational systems with multiple flow channels, an increase in pressure drop in one flow channel, can cause the flow to be diverted to other channels. A burnout can occur in the unstable channel

  6. Ultrasonic flow measurements for irrigation process monitoring

    Science.gov (United States)

    Ziani, Elmostafa; Bennouna, Mustapha; Boissier, Raymond

    2004-02-01

    This paper presents the state of the art of the general principle of liquid flow measurements by ultrasonic method, and problems of flow measurements. We present an ultrasonic flowmeter designed according to smart sensors concept, for the measurement of irrigation water flowing through pipelines or open channels, using the ultrasonic transit time approach. The new flowmeter works on the principle of measuring time delay differences between sound pulses transmitted upstream and downstream in the flowing liquid. The speed of sound in the flowing medium is eliminated as a variable because the flowrate calculations are based on the reciprocals of the transmission times. The transit time difference is digitally measured by means of a suitable, microprocessor controlled logic. This type of ultrasonic flowmeter will be widely used in industry and water management, it is well studied in this work, followed by some experimental results. For pressurized channels, we use one pair of ultrasonic transducer arranged in proper positions and directions of the pipe, in this case, to determine the liquid velocity, a real time on-line analysis taking account the geometries of the hydraulic system, is applied to the obtained ultrasonic data. In the open channels, we use a single or two pairs of ultrasonic emitter-receiver according to the desired performances. Finally, the goals of this work consist in integrating the smart sensor into irrigation systems monitoring in order to evaluate potential advantages and demonstrate their performance, on the other hand, to understand and use ultrasonic approach for determining flow characteristics and improving flow measurements by reducing errors caused by disturbances of the flow profiles.

  7. Monitoring pressure profiles across an airfoil with a fiber Bragg grating sensor array

    Science.gov (United States)

    Papageorgiou, Anthony W.; Parkinson, Luke A.; Karas, Andrew R.; Hansen, Kristy L.; Arkwright, John W.

    2018-02-01

    Fluid flow over an airfoil section creates a pressure difference across the upper and lower surfaces, thus generating lift. Successful wing design is a combination of engineering design and experience in the field, with subtleties in design and manufacture having significant impact on the amount of lift produced. Current methods of airfoil optimization and validation typically involve computational fluid dynamics (CFD) and extensive wind tunnel testing with pressure sensors embedded into the airfoil to measure the pressure over the wing. Monitoring pressure along an airfoil in a wind tunnel is typically achieved using surface pressure taps that consist of hollow tubes running from the surface of the airfoil to individual pressure sensors external to the tunnel. These pressure taps are complex to configure and not ideal for in-flight testing. Fiber Bragg grating (FBG) pressure sensing arrays provide a highly viable option for both wind tunnel and inflight pressure measurement. We present a fiber optic sensor array that can detect positive and negative pressure suitable for validating CFD models of airfoil profile sections. The sensing array presented here consists of 6 independent sensing elements, each capable of a pressure resolution of less than 10 Pa over the range of 70 kPa to 120 kPa. The device has been tested with the sensor array attached to a 90mm chord length airfoil section subjected to low velocity flow. Results show that the arrays are capable of accurately detecting variations of the pressure profile along the airfoil as the angle of attack is varied from zero to the point at which stall occurs.

  8. Pressure-flow relationships in in vitro model of compartment syndrome.

    Science.gov (United States)

    Shrier, I; Magder, S

    1995-07-01

    Compartment syndrome is a condition in which an increase in intramuscular pressure decreases blood flow to skeletal muscle. According to the Starling resistor (i.e., vascular waterfall) model of blood flow, the decrease in flow could occur through an increase in arterial resistance (Rart) or an increase in the critical closing pressure (Pcrit). To determine which explains the decrease in flow, we pump perfused a canine gastrocnemius muscle placed within an airtight box, controlled box pressures (Pbox) so that flow ranged from 100 to 50%, and measured Pcrit, Rart, arterial compliance, small venular pressure (measured by the double-occlusion technique), and venous pressure. An increase in Pbox limited flow mainly through an increase in Pcrit (75-85%), with only small changes in Rart (15-25%) and no change in arterial compliance. Increases in Pbox also produced a vascular waterfall in the venous circulation, but small venular transmural pressure always remained less than control levels. We conclude that increases in Pbox mostly limit blood flow through increases in Pcrit and that Rart plays a minor role. Transmural pressure across the small venules decreases with increases in intramuscular pressure, which contradicts the currently held belief that compartment syndrome is due to a cycle of swelling-ischemia-swelling.

  9. Pressure monitoring during neuroendoscopy : new insights

    NARCIS (Netherlands)

    Dewaele, F.; Kalmar, A. F.; Van Canneyt, K.; Vereecke, H.; Absalom, A.; Caemaert, J.; Struys, M. M. R. F.; Van Roost, D.

    Background. Significant increases in intracranial pressure (ICP) may occur during neuroendoscopic procedures. To detect and prevent serious and sustained increases, ICP should be monitored. At present, controversy exists on the optimal location of the monitoring sensor. Therefore, we conducted an in

  10. Expert monitoring and verbal feedback as sources of performance pressure.

    Science.gov (United States)

    Buchanan, John J; Park, Inchon; Chen, Jing; Mehta, Ranjana K; McCulloch, Austin; Rhee, Joohyun; Wright, David L

    2018-05-01

    The influence of monitoring-pressure and verbal feedback on the performance of the intrinsically stable bimanual coordination patterns of in-phase and anti-phase was examined. The two bimanual patterns were produced under three conditions: 1) no-monitoring, 2) monitoring-pressure (viewed by experts), and 3) monitoring-pressure (viewed by experts) combined with verbal feedback emphasizing poor performance. The bimanual patterns were produced at self-paced movement frequencies. Anti-phase coordination was always less stable than in-phase coordination across all three conditions. When performed under conditions 2 and 3, both bimanual patterns were performed with less variability in relative phase across a wide range of self-paced movement frequencies compared to the no-monitoring condition. Thus, monitoring-pressure resulted in performance stabilization rather than degradation and the presence of verbal feedback had no impact on the influence of monitoring pressure. The current findings are inconsistent with the predictions of explicit monitoring theory; however, the findings are consistent with studies that have revealed increased stability for the system's intrinsic dynamics as a result of attentional focus and intentional control. The results are discussed within the contexts of the dynamic pattern theory of coordination, explicit monitoring theory, and action-focused theories as explanations for choking under pressure. Copyright © 2018. Published by Elsevier B.V.

  11. A piezoelectric micro control valve with integrated capacitive sensing for ambulant blood pressure waveform monitoring

    Science.gov (United States)

    Groen, Maarten S.; Wu, Kai; Brookhuis, Robert A.; van Houwelingen, Marc J.; Brouwer, Dannis M.; Lötters, Joost C.; Wiegerink, Remco J.

    2014-12-01

    We have designed and characterized a MEMS microvalve with built-in capacitive displacement sensing and fitted it with a miniature piezoelectric actuator to achieve active valve control. The integrated displacement sensor enables high bandwidth proportional control of the gas flow through the valve. This is an essential requirement for non-invasive blood pressure waveform monitoring based on following the arterial pressure with a counter pressure. Using the capacitive sensor, we demonstrate negligible hysteresis in the valve control characteristics. Fabrication of the valve requires only two mask steps for deep reactive ion etching (DRIE) and one release etch.

  12. A piezoelectric micro control valve with integrated capacitive sensing for ambulant blood pressure waveform monitoring

    International Nuclear Information System (INIS)

    Groen, Maarten S; Wu, Kai; Brookhuis, Robert A; Lötters, Joost C; Wiegerink, Remco J; Van Houwelingen, Marc J; Brouwer, Dannis M

    2014-01-01

    We have designed and characterized a MEMS microvalve with built-in capacitive displacement sensing and fitted it with a miniature piezoelectric actuator to achieve active valve control. The integrated displacement sensor enables high bandwidth proportional control of the gas flow through the valve. This is an essential requirement for non-invasive blood pressure waveform monitoring based on following the arterial pressure with a counter pressure. Using the capacitive sensor, we demonstrate negligible hysteresis in the valve control characteristics. Fabrication of the valve requires only two mask steps for deep reactive ion etching (DRIE) and one release etch. (paper)

  13. Critical pressure of non-equilibrium two-phase critical flow

    Energy Technology Data Exchange (ETDEWEB)

    Minzer, U [Israel Electric Corp. Ltd., Haifa (Israel)

    1996-12-01

    Critical pressure is defined as the pressure existing at the exit edge of the piping, when it remains constant despite a decrease in the back. According to this definition the critical pressure is larger than the back pressure and for two-phase conditions below saturation pressure. The two-phase critical pressure has a major influence on the two-phase critical flow characteristics. Therefore it is of High significance in calculations of critical mass flux and critical depressurization rate, which are important in the fields of Nuclear Reactor Safety and Industrial Safety. At the Nuclear Reactor Safety field is useful for estimations of the Reactor Cooling System depressurization, the core coolant level, and the pressure build-up in the containment. In the Industrial Safety field it is helpful for estimating the leakage rate of toxic gases Tom liquefied gas pressure vessels, depressurization of pressure vessels, and explosion conditions due to liquefied gas release. For physical description of non-equilibrium two-phase critical flow it would be convenient to divide the flow into two stages. The first stage is the flow of subcooled liquid at constant temperature and uniform pressure drop (i.e., the case of incompressible fluid and uniform piping cross section). The rapid flow of the liquid causes a delay in the boiling of the liquid, which begins to boil below saturation pressure, at thermal non-equilibrium. The boiling is the beginning of the second stage, characterized by a sharp increase of the pressure drop. The liquid temperature on the second stage is almost constant because most of the energy for vaporization is supplied from the large pressure drop The present work will focus on the two-phase critical pressure of water, since water serves as coolant in the vast majority of nuclear power reactors throughout the world. (author).

  14. Critical pressure of non-equilibrium two-phase critical flow

    International Nuclear Information System (INIS)

    Minzer, U.

    1996-01-01

    Critical pressure is defined as the pressure existing at the exit edge of the piping, when it remains constant despite a decrease in the back. According to this definition the critical pressure is larger than the back pressure and for two-phase conditions below saturation pressure. The two-phase critical pressure has a major influence on the two-phase critical flow characteristics. Therefore it is of High significance in calculations of critical mass flux and critical depressurization rate, which are important in the fields of Nuclear Reactor Safety and Industrial Safety. At the Nuclear Reactor Safety field is useful for estimations of the Reactor Cooling System depressurization, the core coolant level, and the pressure build-up in the containment. In the Industrial Safety field it is helpful for estimating the leakage rate of toxic gases Tom liquefied gas pressure vessels, depressurization of pressure vessels, and explosion conditions due to liquefied gas release. For physical description of non-equilibrium two-phase critical flow it would be convenient to divide the flow into two stages. The first stage is the flow of subcooled liquid at constant temperature and uniform pressure drop (i.e., the case of incompressible fluid and uniform piping cross section). The rapid flow of the liquid causes a delay in the boiling of the liquid, which begins to boil below saturation pressure, at thermal non-equilibrium. The boiling is the beginning of the second stage, characterized by a sharp increase of the pressure drop. The liquid temperature on the second stage is almost constant because most of the energy for vaporization is supplied from the large pressure drop The present work will focus on the two-phase critical pressure of water, since water serves as coolant in the vast majority of nuclear power reactors throughout the world. (author)

  15. Self-monitored blood pressure: a role in clinical practice?

    Science.gov (United States)

    Padfield, Paul L

    2002-02-01

    Electronic self-monitoring of blood pressure is increasing in popularity and most international guidelines on the management of hypertension approve cautious use of the technique in the assessment of potentially hypertensive individuals. A recent editorial in the Archives of Internal Medicine suggested that it was "appropriate to encourage the widespread use of self recorded BP as an important adjunct to the clinical care of the patient with hypertension". Such a statement is based on increasing evidence that self-monitoring of blood pressure gives similar information to daytime ambulatory blood pressure -- a now well-established technology in the management of hypertension. Suggested strategies for the use of self-monitoring of blood pressure include monitoring in individuals whose clinical risk status is low enough that they need not necessarily be given medical therapy simply on the basis of a clinic pressure (i.e. at a 10 year risk of cardiovascular disease below 20%). The threshold for defining 'normotension/hypertension' is now regarded as being broadly similar for ABPM and SBPM and is set at 135/85 mmHg. In a recent meta-analysis of all available studies the average difference between these techniques, using the same patients, is -1.7/1.2 mmHg. There is some evidence that careful use of self-monitoring may improve blood pressure control in patients who are otherwise resistant to care. Self-monitoring of blood pressure has now been shown in at least one major prospective study to predict outcome better than clinic pressures and in that setting it now has equivalence to the use of ABPM. There remain issues regarding the availability of validated devices, the quality of training of patients in their use and the possibility that inaccurate recording might occur, either deliberately or by accident. Self-monitoring of blood pressure may well not give the same readings as carefully measured blood pressure by research nurses but its use is clearly superior to

  16. Ambulatory blood pressure monitoring-derived short-term blood pressure variability in primary hyperparathyroidism.

    Science.gov (United States)

    Concistrè, A; Grillo, A; La Torre, G; Carretta, R; Fabris, B; Petramala, L; Marinelli, C; Rebellato, A; Fallo, F; Letizia, C

    2018-04-01

    Primary hyperparathyroidism is associated with a cluster of cardiovascular manifestations, including hypertension, leading to increased cardiovascular risk. The aim of our study was to investigate the ambulatory blood pressure monitoring-derived short-term blood pressure variability in patients with primary hyperparathyroidism, in comparison with patients with essential hypertension and normotensive controls. Twenty-five patients with primary hyperparathyroidism (7 normotensive,18 hypertensive) underwent ambulatory blood pressure monitoring at diagnosis, and fifteen out of them were re-evaluated after parathyroidectomy. Short-term-blood pressure variability was derived from ambulatory blood pressure monitoring and calculated as the following: 1) Standard Deviation of 24-h, day-time and night-time-BP; 2) the average of day-time and night-time-Standard Deviation, weighted for the duration of the day and night periods (24-h "weighted" Standard Deviation of BP); 3) average real variability, i.e., the average of the absolute differences between all consecutive BP measurements. Baseline data of normotensive and essential hypertension patients were matched for age, sex, BMI and 24-h ambulatory blood pressure monitoring values with normotensive and hypertensive-primary hyperparathyroidism patients, respectively. Normotensive-primary hyperparathyroidism patients showed a 24-h weighted Standard Deviation (P blood pressure higher than that of 12 normotensive controls. 24-h average real variability of systolic BP, as well as serum calcium and parathyroid hormone levels, were reduced in operated patients (P blood pressure variability is increased in normotensive patients with primary hyperparathyroidism and is reduced by parathyroidectomy, and may potentially represent an additional cardiovascular risk factor in this disease.

  17. Pressure drop in flashing flow through obstructions

    International Nuclear Information System (INIS)

    Weinle, M.E.; Johnston, B.S.

    1985-01-01

    An experiment was designed to investigate the pressure drop for flashing flow across obstructions of different geometries at various flow rates. Tests were run using two different orifices to determine if the two-phase pressure drop could be characterized by the single phase loss coefficient and the general behavior of the two-phase multiplier. For the geometries studied, it was possible to correlate the multiplier in a geometry-independent fashion

  18. Influence of cerebrovascular resistance on the dynamic relationship between blood pressure and cerebral blood flow in humans.

    Science.gov (United States)

    Smirl, J D; Tzeng, Y C; Monteleone, B J; Ainslie, P N

    2014-06-15

    We examined the hypothesis that changes in the cerebrovascular resistance index (CVRi), independent of blood pressure (BP), will influence the dynamic relationship between BP and cerebral blood flow in humans. We altered CVRi with (via controlled hyperventilation) and without [via indomethacin (INDO, 1.2 mg/kg)] changes in PaCO2. Sixteen subjects (12 men, 27 ± 7 yr) were tested on two occasions (INDO and hypocapnia) separated by >48 h. Each test incorporated seated rest (5 min), followed by squat-stand maneuvers to increase BP variability and improve assessment of the pressure-flow dynamics using linear transfer function analysis (TFA). Beat-to-beat BP, middle cerebral artery velocity (MCAv), posterior cerebral artery velocity (PCAv), and end-tidal Pco2 were monitored. Dynamic pressure-flow relations were quantified using TFA between BP and MCAv/PCAv in the very low and low frequencies through the driven squat-stand maneuvers at 0.05 and 0.10 Hz. MCAv and PCAv reductions by INDO and hypocapnia were well matched, and CVRi was comparably elevated (P flow dynamics. These findings are consistent with the concept of CVRi being a key factor that should be considered in the correct interpretation of cerebral pressure-flow dynamics as indexed using TFA metrics. Copyright © 2014 the American Physiological Society.

  19. Flow rate-pressure drop relation for deformable shallow microfluidic channels

    Science.gov (United States)

    Christov, Ivan C.; Cognet, Vincent; Shidhore, Tanmay C.; Stone, Howard A.

    2018-04-01

    Laminar flow in devices fabricated from soft materials causes deformation of the passage geometry, which affects the flow rate--pressure drop relation. For a given pressure drop, in channels with narrow rectangular cross-section, the flow rate varies as the cube of the channel height, so deformation can produce significant quantitative effects, including nonlinear dependence on the pressure drop [{Gervais, T., El-Ali, J., G\\"unther, A. \\& Jensen, K.\\ F.}\\ 2006 Flow-induced deformation of shallow microfluidic channels.\\ \\textit{Lab Chip} \\textbf{6}, 500--507]. Gervais et. al. proposed a successful model of the deformation-induced change in the flow rate by heuristically coupling a Hookean elastic response with the lubrication approximation for Stokes flow. However, their model contains a fitting parameter that must be found for each channel shape by performing an experiment. We present a perturbation approach for the flow rate--pressure drop relation in a shallow deformable microchannel using the theory of isotropic quasi-static plate bending and the Stokes equations under a lubrication approximation (specifically, the ratio of the channel's height to its width and of the channel's height to its length are both assumed small). Our result contains no free parameters and confirms Gervais et. al.'s observation that the flow rate is a quartic polynomial of the pressure drop. The derived flow rate--pressure drop relation compares favorably with experimental measurements.

  20. Effective flow performances and dialysis doses delivered with permanent catheters: a 24-month comparative study of permanent catheters versus arterio-venous vascular accesses.

    Science.gov (United States)

    Canaud, Bernard; Leray-Moragues, Hélène; Kerkeni, Nadia; Bosc, Jean-Yves; Martin, Katja

    2002-07-01

    Permanent venous catheters have emerged as a long-term vascular access option for renal replacement therapy in end-stage renal disease patients. The design and venous location of catheter devices bear intrinsic flow limitations that may negatively affect the adequacy of dialysis and the patient outcome. There is limited data comparing the long-term dialysis adequacy delivered with permanent catheters vs arterio-venous vascular accesses (AVA). To explore this problem, we conducted a prospective 24-month trial comparing the flow performances and dialysis dose (Kt/Vdp) deliveries of both access options in a group of 42 haemodialysis patients during two study phases. During the first 12 months the patients completed a treatment period by means of permanent dual silicone catheters (DualKT). Then they were transferred to an AVA (40 native arterio-venous fistulas and two PTFE grafts) and monitored for an additional 12-month period. Assessments of flow adequacy and dialysis quantification were performed monthly. Dialysis adequacy was achieved in all cases. No patient had to be transferred prematurely to the AVA because of catheter failure. Three catheters had to be replaced due to bacteraemia in three patients. The mean effective blood flow rates achieved were 316+/-3.5 ml/min and 340+/-3.3 ml/min with DualKT and AVA, respectively, for a pre-set machine blood flow of 348+/-2.2 ml/min. Recirculation rates evaluated with the 'slow blood flow' method were 8.6+/-0.6 and 12.1+/-0.8% for DualKT and AVA using mean values of the solute markers urea and creatinine. Due to the possibility of a comparison veno-venous vs arterio-venous blood circulation, a corrected arterio-venous access recirculation could be derived from the difference between the two, which was around 3%. The blood flow resistance of the DualKT was slightly higher than with AVA as indicated by venous pressure differences. Kt/Vdp delivered was 1.37+/-0.02 and 1.45+/-0.02 with DualKT and AVA access respectively. The

  1. Determination of mean pressure from PIV in compressible flows using the Reynolds-averaging approach

    Science.gov (United States)

    van Gent, Paul L.; van Oudheusden, Bas W.; Schrijer, Ferry F. J.

    2018-03-01

    The feasibility of computing the flow pressure on the basis of PIV velocity data has been demonstrated abundantly for low-speed conditions. The added complications occurring for high-speed compressible flows have, however, so far proved to be largely inhibitive for the accurate experimental determination of instantaneous pressure. Obtaining mean pressure may remain a worthwhile and realistic goal to pursue. In a previous study, a Reynolds-averaging procedure was developed for this, under the moderate-Mach-number assumption that density fluctuations can be neglected. The present communication addresses the accuracy of this assumption, and the consistency of its implementation, by evaluating of the relevance of the different contributions resulting from the Reynolds-averaging. The methodology involves a theoretical order-of-magnitude analysis, complemented with a quantitative assessment based on a simulated and a real PIV experiment. The assessments show that it is sufficient to account for spatial variations in the mean velocity and the Reynolds-stresses and that temporal and spatial density variations (fluctuations and gradients) are of secondary importance and comparable order-of-magnitude. This result permits to simplify the calculation of mean pressure from PIV velocity data and to validate the approximation of neglecting temporal and spatial density variations without having access to reference pressure data.

  2. Blood pressure monitoring: theory and practice. European Society of Hypertension Working Group on Blood Pressure Monitoring and Cardiovascular Variability Teaching Course Proceedings.

    Science.gov (United States)

    Stergiou, George S; Palatini, Paolo; Asmar, Roland; Bilo, Grzegorz; de la Sierra, Alejandro; Head, Geoff; Kario, Kazuomi; Mihailidou, Anastasia; Wang, Jiguang; Mancia, Giuseppe; O'Brien, Eoin; Parati, Gianfranco

    2018-02-01

    The European Society of Hypertension (ESH) Working Group on Blood Pressure (BP) Monitoring and Cardiovascular Variability organized a Teaching Course on 'Blood Pressure Monitoring: Theory and Practice' during the 2017 ESH Meeting in Milan, Italy. This course performed by 11 international BP monitoring experts covered key topics of BP monitoring, including office BP measurement, ambulatory BP monitoring, home BP monitoring, ambulatory versus home BP, white-coat and masked hypertension, cuff use, and BP variability. This article presents a summary of the proceedings of the ESH BP Monitoring Teaching Course, including essential information, practical issues, and recommendations on the clinical application of BP monitoring methods, aiming to the optimal management of patients with suspected or diagnosed hypertension.

  3. Ethernet Flow Monitoring with IPFIX

    NARCIS (Netherlands)

    Hofstede, R.J.; Drago, Idilio; Sperotto, Anna; Pras, Aiko

    The increasing amount of network traffic and the huge bandwidth needed to carry it requires managers to use scalable solutions to monitor their networks. Nowadays, flow-based techniques, such as Cisco’s NetFlow, provide aggregated network data and an overview of network activity at the IP layer.

  4. The effect of valve strategy on in-cylinder flow and combustion

    Energy Technology Data Exchange (ETDEWEB)

    Soederberg, F

    1997-01-01

    This paper examines the effects of different valve strategies and their effect on in-cylinder flow and combustion. A conventional four valve per cylinder otto engine was modified to enable optical access. The flow measurements were made with a two-component laser Doppler velocimetry system. The combustion was monitored by running pressure data from a pressure transducer through a one-zone heat release model. The results show that when the valves operate normally a barrel flow is present and when one valve is closed a swirling flow occurs. No increase in turbulence was found with later phasing, except in the case of very late inlet valve opening and port deactivation. This resulted in a jet with high turbulence, making the combustion fast and stable, even with a very lean mixture ({lambda}=1.8). 6 refs, 44 figs, 4 tabs

  5. Time-averaged second-order pressure and velocity measurements in a pressurized oscillating flow prime mover

    Energy Technology Data Exchange (ETDEWEB)

    Paridaens, Richard [DynFluid, Arts et Metiers, 151 boulevard de l' Hopital, Paris (France); Kouidri, Smaine [LIMSI-CNRS, Orsay Cedex (France)

    2016-11-15

    Nonlinear phenomena in oscillating flow devices cause the appearance of a relatively minor secondary flow known as acoustic streaming, which is superimposed on the primary oscillating flow. Knowledge of control parameters, such as the time-averaged second-order velocity and pressure, would elucidate the non-linear phenomena responsible for this part of the decrease in the system's energetic efficiency. This paper focuses on the characterization of a travelling wave oscillating flow engine by measuring the time-averaged second order pressure and velocity. Laser Doppler velocimetry technique was used to measure the time-averaged second-order velocity. As streaming is a second-order phenomenon, its measurement requires specific settings especially in a pressurized device. Difficulties in obtaining the proper settings are highlighted in this study. The experiments were performed for mean pressures varying from 10 bars to 22 bars. Non-linear effect does not constantly increase with pressure.

  6. Non-invasive pulmonary blood flow analysis and blood pressure mapping derived from 4D flow MRI

    Science.gov (United States)

    Delles, Michael; Rengier, Fabian; Azad, Yoo-Jin; Bodenstedt, Sebastian; von Tengg-Kobligk, Hendrik; Ley, Sebastian; Unterhinninghofen, Roland; Kauczor, Hans-Ulrich; Dillmann, Rüdiger

    2015-03-01

    In diagnostics and therapy control of cardiovascular diseases, detailed knowledge about the patient-specific behavior of blood flow and pressure can be essential. The only method capable of measuring complete time-resolved three-dimensional vector fields of the blood flow velocities is velocity-encoded magnetic resonance imaging (MRI), often denoted as 4D flow MRI. Furthermore, relative pressure maps can be computed from this data source, as presented by different groups in recent years. Hence, analysis of blood flow and pressure using 4D flow MRI can be a valuable technique in management of cardiovascular diseases. In order to perform these tasks, all necessary steps in the corresponding process chain can be carried out in our in-house developed software framework MEDIFRAME. In this article, we apply MEDIFRAME for a study of hemodynamics in the pulmonary arteries of five healthy volunteers. The study included measuring vector fields of blood flow velocities by phase-contrast MRI and subsequently computing relative blood pressure maps. We visualized blood flow by streamline depictions and computed characteristic values for the left and the right pulmonary artery (LPA and RPA). In all volunteers, we observed a lower amount of blood flow in the LPA compared to the RPA. Furthermore, we visualized blood pressure maps using volume rendering and generated graphs of pressure differences between the LPA, the RPA and the main pulmonary artery. In most volunteers, blood pressure was increased near to the bifurcation and in the proximal LPA, leading to higher average pressure values in the LPA compared to the RPA.

  7. Get the Most Out of Home Blood Pressure Monitoring

    Science.gov (United States)

    Get the most out of home blood pressure monitoring Checking your blood pressure at home is an important part of managing ... monitors might not give you an accurate reading. Most pharmacies, medical supply stores and some websites sell ...

  8. Sludge pipe flow pressure drop prediction using composite power ...

    African Journals Online (AJOL)

    Sludge pipe flow pressure drop prediction using composite power-law friction ... Water SA. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue ... When predicting pressure gradients for the flow of sludges in pipes, the ...

  9. Simultaneous velocity and pressure quantification using pressure-sensitive flow tracers in air

    Science.gov (United States)

    Zhang, Peng; Peterson, Sean; Porfiri, Maurizio

    2017-11-01

    Particle-based measurement techniques for assessing the velocity field of a fluid have advanced rapidly over the past two decades. Full-field pressure measurement techniques have remained elusive, however. In this work, we aim to demonstrate the possibility of direct simultaneous planar velocity and pressure measurement of a high speed aerodynamic flow by employing novel pressure-sensitive tracer particles for particle image velocimetry (PIV). Specifically, the velocity and pressure variations of an airflow through a converging-diverging channel are studied. Polystyrene microparticles embedded with a pressure-sensitive phosphorescent dye-platinum octaethylporphyrin (PtOEP)-are used as seeding particles. Due to the oxygen quenching effect, the emission lifetime of PtOEP is highly sensitive to the oxygen concentration, that is, the partial pressure of oxygen, in the air. Since the partial pressure of oxygen is linearly proportional to the air pressure, we can determine the air pressure through the phosphorescence emission lifetime of the dye. The velocity field is instead obtained using traditional PIV methods. The particles have a pressure resolution on the order of 1 kPa, which may be improved by optimizing the particle size and dye concentration to suit specific flow scenarios. This work was supported by the National Science Foundation under Grant Number CBET-1332204.

  10. Study on flow regimes of high-pressure and dense-phase pneumatic conveying

    International Nuclear Information System (INIS)

    Lu Peng; Chen Xiaoping; Liang Cai; Pu Wenhao; Zhou Yun; Xu Pan; Zhao Changsui

    2009-01-01

    High-pressure and dense-phase pneumatic conveying of pulverized coal is a key technology in the field of large-scale entrained bed coal gasification. Flow regime plays an important role in two-phase flow because it affects not only flow behavior and safety operation, but also the reliability of practical processes. Few references and experiences in high-pressure and dense-phase conveying are available, especially for the flow regimes. And because of the high stickiness and electrostatic attraction of pulverized coal to the pipe wall, it is very difficult to make out the flow regimes in the conveying pipe by visualization method. Thus quartz powder was chosen as the conveyed material to study the flow regime. High-speed digital video camera was employed to photograph the flow patterns. Experiments were conducted on a pilot scale experimental setup at the pressure up to 3.6MPa. With the decrease in superficial gas velocity, three distinguishable flow regimes were observed: stratified flow, dune flow and plug flow. The characteristics of pressure traces acquired by high frequency response pressure transmitter and their EMD (Empirical Mode Decomposition) characteristics were correlated strongly with the flow regimes. Combining high-speed photography and pressure signal analysis together can make the recognition of flow patterns in the high-pressure and dense-phase pneumatic conveying system more accurate. The present work will lead to better understanding of the flow regime transition under high-pressure.

  11. Pressure-Flow Characteristics of Normal and Disordered Esophageal Motor Patterns

    NARCIS (Netherlands)

    Singendonk, Maartje M. J.; Kritas, Stamatiki; Cock, Charles; Ferris, Lara F.; McCall, Lisa; Rommel, Nathalie; van Wijk, Michiel P.; Benninga, Marc A.; Moore, David; Omari, Taher I.

    2015-01-01

    Objective To perform pressure-flow analysis (PFA) in a cohort of pediatric patients who were referred for diagnostic manometric investigation. Study design PFA was performed using purpose designed Matlab-based software. The pressure-flow index (PFI), a composite measure of bolus pressurization

  12. Automatic algorithm for monitoring systolic pressure variation and difference in pulse pressure.

    Science.gov (United States)

    Pestel, Gunther; Fukui, Kimiko; Hartwich, Volker; Schumacher, Peter M; Vogt, Andreas; Hiltebrand, Luzius B; Kurz, Andrea; Fujita, Yoshihisa; Inderbitzin, Daniel; Leibundgut, Daniel

    2009-06-01

    Difference in pulse pressure (dPP) reliably predicts fluid responsiveness in patients. We have developed a respiratory variation (RV) monitoring device (RV monitor), which continuously records both airway pressure and arterial blood pressure (ABP). We compared the RV monitor measurements with manual dPP measurements. ABP and airway pressure (PAW) from 24 patients were recorded. Data were fed to the RV monitor to calculate dPP and systolic pressure variation in two different ways: (a) considering both ABP and PAW (RV algorithm) and (b) ABP only (RV(slim) algorithm). Additionally, ABP and PAW were recorded intraoperatively in 10-min intervals for later calculation of dPP by manual assessment. Interobserver variability was determined. Manual dPP assessments were used for comparison with automated measurements. To estimate the importance of the PAW signal, RV(slim) measurements were compared with RV measurements. For the 24 patients, 174 measurements (6-10 per patient) were recorded. Six observers assessed dPP manually in the first 8 patients (10-min interval, 53 measurements); no interobserver variability occurred using a computer-assisted method. Bland-Altman analysis showed acceptable bias and limits of agreement of the 2 automated methods compared with the manual method (RV: -0.33% +/- 8.72% and RV(slim): -1.74% +/- 7.97%). The difference between RV measurements and RV(slim) measurements is small (bias -1.05%, limits of agreement 5.67%). Measurements of the automated device are comparable with measurements obtained by human observers, who use a computer-assisted method. The importance of the PAW signal is questionable.

  13. Comparison of deliverable and exhaustible pressurized air flow rates in laboratory gloveboxes

    International Nuclear Information System (INIS)

    Compton, J.A.

    1994-01-01

    Calculations were performed to estimate the maximum credible flow rates of pressurized air into Plutonium Process Support Laboratories gloveboxes. Classical equations for compressible fluids were used to estimate the flow rates. The calculated maxima were compared to another's estimates of glovebox exhaust flow rates and corresponding glovebox internal pressures. No credible pressurized air flow rate will pressurize a glovebox beyond normal operating limits. Unrestricted use of the pressurized air supply is recommended

  14. Two zero-flow pressure intercepts exist in autoregulating isolated skeletal muscle.

    Science.gov (United States)

    Braakman, R; Sipkema, P; Westerhof, N

    1990-06-01

    The autoregulating vascular bed of the isolated canine extensor digitorum longus muscle was investigated for the possible existence of two positive zero-flow pressure axis intercepts, a tone-dependent one and a tone-independent one. An isolated preparation, perfused with autologous blood, was used to exclude effects of collateral flow and nervous and humoral regulation while autoregulation was left intact [mean autoregulatory gain 0.50 +/- 0.24 (SD)]. In a first series of experiments, the steady-state (zero flow) pressure axis intercept [mean 8.9 +/- 2.6 (SD) mmHg, tone independent] and the instantaneous (zero flow) pressure axis intercept [mean 28.5 +/- 9.9 (SD) mmHg, tone dependent] were determined as a function of venous pressure (range: 0-45 mmHg) and were independent of venous pressure until the venous pressure exceeded their respective values. Beyond this point the relations between the venous pressure and the steady-state and instantaneous pressure axis intercept followed the line of identity. The findings agree with the predictions of the vascular waterfall model. In a second series it was shown by means of administration of vasoactive drugs that the instantaneous pressure axis intercept is tone dependent, whereas the steady-state pressure axis intercept is not. It is concluded that there is a (proximal) tone-dependent zero-flow pressure at the arteriolar level and a (distal) tone-independent zero-flow pressure at the venous level.

  15. Pressure algorithm for elliptic flow calculations with the PDF method

    Science.gov (United States)

    Anand, M. S.; Pope, S. B.; Mongia, H. C.

    1991-01-01

    An algorithm to determine the mean pressure field for elliptic flow calculations with the probability density function (PDF) method is developed and applied. The PDF method is a most promising approach for the computation of turbulent reacting flows. Previous computations of elliptic flows with the method were in conjunction with conventional finite volume based calculations that provided the mean pressure field. The algorithm developed and described here permits the mean pressure field to be determined within the PDF calculations. The PDF method incorporating the pressure algorithm is applied to the flow past a backward-facing step. The results are in good agreement with data for the reattachment length, mean velocities, and turbulence quantities including triple correlations.

  16. Helically symmetric equilibria with pressure anisotropy and incompressible plasma flow

    Science.gov (United States)

    Evangelias, A.; Kuiroukidis, A.; Throumoulopoulos, G. N.

    2018-02-01

    We derive a generalized Grad-Shafranov equation governing helically symmetric equilibria with pressure anisotropy and incompressible flow of arbitrary direction. Through the most general linearizing ansatz for the various free surface functions involved therein, we construct equilibrium solutions and study their properties. It turns out that pressure anisotropy can act either paramegnetically or diamagnetically, the parallel flow has a paramagnetic effect, while the non-parallel component of the flow associated with the electric field has a diamagnetic one. Also, pressure anisotropy and flow affect noticeably the helical current density.

  17. Pressure effects on viscosity and flow stability of polyethylene melts during extrusion

    Energy Technology Data Exchange (ETDEWEB)

    Carreras, Enric Santanach; Kissi, Nadia El; Piau, Jean-Michel; Toussaint, Fabrice; Nigen, Sophie [Domaine Universitaire, Laboratoire de Rheologie, Universite Joseph Fourier-Grenoble I, Institut National Polytechnique de Grenoble, CNRS (UMR 5520), B. P. 53, Grenoble cedex 9 (France)

    2006-01-01

    In the present work, the effects of pressure on the viscosity and flow stability of four commercial grade polyethylenes (PEs) have been studied: linear-low-density polyethylene copolymer, high-density polyethylene, metallocene polyethylenes with short-chain branches (mPE-SCB), and metallocene polyethylenes with long chain branching (mPE-LCB). The range of shear rates considered covers both stable and unstable flow regimes. ''Enhanced exit-pressure'' experiments have been performed attaining pressures of the order of 500 x 10{sup 5} Pa at the die exit. The necessary experimental conditions have been clearly defined so that dissipative heating can be neglected and pressure effects isolated. The results obtained show an exponential increase in both shear and entrance-flow pressure drop with mean pressure when shear rate is fixed and as long as flow is stable. These pressure effects are described by two pressure coefficients, {beta}{sub S} under shear and, {beta}{sub E} under elongation, that are calculated using time-pressure superposition and that are independent of mean pressure and flow rate. For three out of four PE, pressure coefficient values can be considered equal under shear and under elongation. However, for the mPE-LCB, the pressure coefficient under elongation is found to be about 30% lower than under shear. Flow instabilities in the form of oscillating flows or of upstream instabilities appear at lower shear rates as mean pressure increases. Nevertheless, the critical shear stress at which they are triggered remains independent of mean pressure. Moreover, it is found that the {beta}{sub S} values obtained for stable flows do not differ much from the values obtained during upstream instability regimes, and differ really from pressure effects observed under oscillating flow and slip conditions. (orig.)

  18. A continuum model for pressure-flow relationship in human pulmonary circulation.

    Science.gov (United States)

    Huang, Wei; Zhou, Qinlian; Gao, Jian; Yen, R T

    2011-06-01

    A continuum model was introduced to analyze the pressure-flow relationship for steady flow in human pulmonary circulation. The continuum approach was based on the principles of continuum mechanics in conjunction with detailed measurement of vascular geometry, vascular elasticity and blood rheology. The pulmonary arteries and veins were considered as elastic tubes and the "fifth-power law" was used to describe the pressure-flow relationship. For pulmonary capillaries, the "sheet-flow" theory was employed and the pressure-flow relationship was represented by the "fourth-power law". In this paper, the pressure-flow relationship for the whole pulmonary circulation and the longitudinal pressure distribution along the streamlines were studied. Our computed data showed general agreement with the experimental data for the normal subjects and the patients with mitral stenosis and chronic bronchitis in the literature. In conclusion, our continuum model can be used to predict the changes of steady flow in human pulmonary circulation.

  19. Accuracy of home blood pressure readings: monitors and operators.

    Science.gov (United States)

    Stryker, Trina; Wilson, Merne; Wilson, Thomas W

    2004-06-01

    To evaluate the accuracy of automated digital blood pressure monitoring devices and operators in the community. Also, we tested the effects of a simple education program, and looked for arm-arm differences. Subjects who had bought their own automated digital blood pressure monitor were recruited via an advertisement in the local newspaper. On arrival, they were asked to record their blood pressure exactly as they would at home. The investigator noted any technique deficiencies then corrected them. Blood pressures were then recorded by the investigator and the subject, on opposite arms, simultaneously, and repeated with the arms switched. Finally, subjects recorded their blood pressure again. The subjects' readings were compared to the average of monitor and mercury readings using Bland-Altman methods. A total of 80 subjects were tested. Before educating, subjects' systolic blood pressure (SBP) readings were +5.8+/-6.4 (standard deviation) mmHg greater than the mean of all readings, and diastolic blood pressure (DBP) were +1.3+/-4.0 mmHg; after educating they were +1.3+/-4.0 and -1.3+/-2.7 respectively. The monitors, as a group, were accurate, and met British Hypertension Society and AAMI highest standards. We found no differences among monitors that had been validated (n=26) and those that had not. There were differences between the arms: 5.3+/-5.2 mmHg for SBP and 3.4+/-3.3 mmHg for DBP. Most patients had never been informed by anyone of proper blood pressure measuring techniques. We conclude that home blood pressure measurement, as practiced in our community, is prone to error, mostly due to mistakes by the operator. These can easily be corrected, so that readings become more accurate. Attention should be paid to arm-arm differences.

  20. Pressure-driven peristaltic flow

    International Nuclear Information System (INIS)

    Mingalev, S V; Lyubimov, D V; Lyubimova, T P

    2013-01-01

    The peristaltic motion of an incompressible fluid in two-dimensional channel is investigated. Instead of fixing the law of wall's coordinate variation, the law of pressure variation on the wall is fixed and the border's coordinate changes to provide the law of pressure variation on the wall. In case of small amplitude of pressure-variation on the wall A, expansion wave propagates along the length of channel and the wave results in the peristaltic transport of fluid. In the case of large A, the channel divides into two parts. The small pulsating part in the end of the tube creates the flow as a human heart, while the other big part loses this function. The solution of problem for the first peristaltic mode is stable, while the solution for the second 'heart' mode is unstable and depends heavily on boundary conditions.

  1. Systems and Sensors for Debris-flow Monitoring and Warning

    Directory of Open Access Journals (Sweden)

    Lorenzo Marchi

    2008-04-01

    Full Text Available Debris flows are a type of mass movement that occurs in mountain torrents. They consist of a high concentration of solid material in water that flows as a wave with a steep front. Debris flows can be considered a phenomenon intermediate between landslides and water floods. They are amongst the most hazardous natural processes in mountainous regions and may occur under different climatic conditions. Their destructiveness is due to different factors: their capability of transporting and depositing huge amounts of solid materials, which may also reach large sizes (boulders of several cubic meters are commonly transported by debris flows, their steep fronts, which may reach several meters of height and also their high velocities. The implementation of both structural and nonstructural control measures is often required when debris flows endanger routes, urban areas and other infrastructures. Sensor networks for debris-flow monitoring and warning play an important role amongst non-structural measures intended to reduce debris-flow risk. In particular, debris flow warning systems can be subdivided into two main classes: advance warning and event warning systems. These two classes employ different types of sensors. Advance warning systems are based on monitoring causative hydrometeorological processes (typically rainfall and aim to issue a warning before a possible debris flow is triggered. Event warning systems are based on detecting debris flows when these processes are in progress. They have a much smaller lead time than advance warning ones but are also less prone to false alarms. Advance warning for debris flows employs sensors and techniques typical of meteorology and hydrology, including measuring rainfall by means of rain gauges and weather radar and monitoring water discharge in headwater streams. Event warning systems use different types of sensors, encompassing ultrasonic or radar gauges, ground vibration sensors, videocameras, avalanche

  2. CFD simulation of flow-pressure characteristics of a pressure control valve for automotive fuel supply system

    International Nuclear Information System (INIS)

    Wu, Dazhuan; Li, Shiyang; Wu, Peng

    2015-01-01

    Highlights: • Direct CFD method for flow-pressure characteristic of a pressure control valve. • Fitted and interpreted the constants of the spool hydraulic force equation. • Established a flow coefficient function of both valve opening and pressure drop. • Developed an indirect CFD method based on the valve-governing equations. - Abstract: This study aims to elaborate on specific computational fluid dynamics (CFD) simulation methods for fitting the flow-pressure curve of a pressure control valve, which is spring-load valve widely used in the automotive fuel supply system. Given that the couple mechanism exists between the flow field in the valve and the spring system, numerous researchers chose to fit the characteristic curve with experimental approaches but scarcely focused on CFD methods. A direct CFD method is introduced in this study to solve this problem. Two evaluation criteria are used to determine whether the internal flow is physically real. An experiment is conducted to verify the simulation results, and the accuracy of this CFD method is proved. However, it is designed to solve one operating condition with fixed spring parameters and the accuracy depends on the amount of operating conditions. Thus, an indirect CFD method is developed based on the well-elaborated valve-governing equations to improve the efficiency and broaden the application extension. This method aims to simulate the exact value of the equation constants to uncouple the flow by numerical method. It is capable of dealing with changed operating conditions and varied spring parameters, and the results are also verified. The visualization of the internal flow provides a better understanding of the flow fields in the valve. The valve gap directly influences the hydraulic force distribution on the spool and causes most pressure loss. The physical meaning of the function constants are explained based on the flow analysis

  3. Correlation between cerebral hemodynamic and perfusion pressure changes in non-human primates

    Science.gov (United States)

    Ruesch, A.; Smith, M. A.; Wollstein, G.; Sigal, I. A.; Nelson, S.; Kainerstorfer, J. M.

    2017-02-01

    The mechanism that maintains a stable blood flow in the brain despite changes in cerebral perfusion pressure (CPP), and therefore guaranties a constant supply of oxygen and nutrients to the neurons, is known as cerebral auto-regulation (CA). In a certain range of CPP, blood flow is mediated by a vasomotor adjustment in vascular resistance through dilation of blood vessels. CA is known to be impaired in diseases like traumatic brain injury, Parkinson's disease, stroke, hydrocephalus and others. If CA is impaired, blood flow and pressure changes are coupled and thee oxygen supply might be unstable. Lassen's blood flow auto-regulation curve describes this mechanism, where a plateau of stable blood flow in a specific range of CPP corresponds to intact auto-regulation. Knowing the limits of this plateau and maintaining CPP within these limits can improve patient outcome. Since CPP is influenced by both intracranial pressure and arterial blood pressure, long term changes in either can lead to auto-regulation impairment. Non-invasive methods for monitoring blood flow auto-regulation are therefore needed. We propose too use Near infrared spectroscopy (NIRS) too fill this need. NIRS is an optical technique, which measures microvascular changes in cerebral hemoglobin concentration. We performed experiments on non-human primates during exsanguination to demonstrate that thee limits of blood flow auto-regulation can be accessed with NIRS.

  4. Beat-to-Beat Blood Pressure Monitor

    Science.gov (United States)

    Lee, Yong Jin

    2012-01-01

    This device provides non-invasive beat-to-beat blood pressure measurements and can be worn over the upper arm for prolonged durations. Phase and waveform analyses are performed on filtered proximal and distal photoplethysmographic (PPG) waveforms obtained from the brachial artery. The phase analysis is used primarily for the computation of the mean arterial pressure, while the waveform analysis is used primarily to obtain the pulse pressure. Real-time compliance estimate is used to refine both the mean arterial and pulse pressures to provide the beat-to-beat blood pressure measurement. This wearable physiological monitor can be used to continuously observe the beat-to-beat blood pressure (B3P). It can be used to monitor the effect of prolonged exposures to reduced gravitational environments and the effectiveness of various countermeasures. A number of researchers have used pulse wave velocity (PWV) of blood in the arteries to infer the beat-to-beat blood pressure. There has been documentation of relative success, but a device that is able to provide the required accuracy and repeatability has not yet been developed. It has been demonstrated that an accurate and repeatable blood pressure measurement can be obtained by measuring the phase change (e.g., phase velocity), amplitude change, and distortion of the PPG waveforms along the brachial artery. The approach is based on comparing the full PPG waveform between two points along the artery rather than measuring the time-of-flight. Minimizing the measurement separation and confining the measurement area to a single, well-defined artery allows the waveform to retain the general shape between the two measurement points. This allows signal processing of waveforms to determine the phase and amplitude changes.

  5. Long term monitoring of water production flow rates in boreholes in the Callovo-Oxfordian argillaceous rock

    International Nuclear Information System (INIS)

    Vinsot, A.; Delay, J.; La Vaissiere, R. de; Cruchaudet, M.

    2010-01-01

    Document available in extended abstract form only. Water production was observed in several boreholes in the Callovo-Oxfordian argillaceous rock (COx). These boreholes were implemented in 2005 in the Andra's Underground Research Laboratory (URL) at more than 400 m in depth. Despite the low COx permeability: close to 10-13 m/s, two original experimental setups made it possible to monitor water production flow rates ranging from 0.5 to 50 mL/day during 3 to 4 years in 4 boreholes. This contribution describes the water flow rate evaluation methods and the results obtained from several experimental phases which may be considered as a series of constant pressure production tests. The first experimental concept was based on seepage water collection. It consisted in filling with gas the interval of an ascending borehole at a pressure close to 1 bar and closing it. The hydraulic pressure in the rock surrounding the sealed interval was higher than 30 bars. Due to the hydraulic pressure difference between the interval and the surrounding rock, the interstitial water of the formation flowed into the interval, accumulated at its base by gravity and was pumped out at a controlled flow rate. The pumping rate was adjusted so that the water level would not exceed 40 cm inside the 5-meter-long interval. The water level was deduced from the difference between two absolute pressure measurements: one above the water surface in the gas phase and the other at the bottom of the water column. The total volume of the daily produced formation water was obtained by adding the water volume pumped out during the day and the water volume difference inside the interval between the beginning and the end of the day. This kind of experiment was performed in two boreholes. The second experimental concept was based on water circulation. It consisted in filling with water the interval of a descending borehole. Two water circulation lines and one pressure control line linked the test interval to

  6. Pressure data for various flow channels in proton exchange membrane (PEM) fuel cell

    International Nuclear Information System (INIS)

    Cho, Son Ah; Lee, Pil Hyong; Han, Sang Seok; Hwang, Sang Soon

    2008-01-01

    Micro flow channels in flow plates of fuel cells have become much narrower and longer to improve reactant flow distribution leading to increase of pumping power. Therefore it is very important to minimize the pressure drops in the flow channel because increased pumping power reduces overall efficiency. We investigated pressure drops in a micro flow channel at the anode and cathode compared to pressure losses for cold flow in straight, bended and serpentine channels. The results show that friction factors for cold flow channels could be used for parallel and bended flow channel designs for fuel cells. Pressure drop in the serpentine flow channel is the lowest among all flow channels due to bypass flow across the gas diffusion layer under reactive flow condition, although its pressure drop is highest for a cold flow condition. So the effect of bypass flow for serpentine flow channels should be considered when designing flow channels

  7. Effects of atmospheric pressure conditions on flow rate of an elastomeric infusion pump.

    Science.gov (United States)

    Wang, Jong; Moeller, Anna; Ding, Yuanpang Samuel

    2012-04-01

    The effects of pressure conditions, both hyperbaric and hypobaric, on the flow rate of an elastomeric infusion pump were investigated. The altered pressure conditions were tested with the restrictor outlet at two different conditions: (1) at the same pressure condition as the Infusor elastomeric balloon and (2) with the outlet exposed to ambient conditions. Five different pressure conditions were tested. These included ambient pressure (98-101 kilopascals [kPa]) and test pressures controlled to be 10 or 20 kPa below or 75 or 150 kPa above the ambient pressure. A theoretical calculation based on the principles of fluid mechanics was also used to predict the pump's flow rate at various ambient conditions. The conditions in which the Infusor elastomeric pump and restrictor outlet were at the same pressure gave rise to average flow rates within the ±10% tolerance of the calculated target flow rate of 11 mL/hr. The flow rate of the Infusor pump decreased when the pressure conditions changed from hypobaric to ambient. The flow rate increased when the pressure conditions changed from hyperbaric to ambient. The flow rate of the Infusor elastomeric pump was not affected when the balloon reservoir and restrictor outlet were at the same pressure. The flow rate varied from 58.54% to 377.04% of the labeled flow rate when the pressure applied to the reservoir varied from 20 kPa below to 150 kPa above the pressure applied to the restrictor outlet, respectively. The maximum difference between observed flow rates and those calculated by applying fluid mechanics was 4.9%.

  8. Zonal flows in tokamaks with anisotropic pressure

    International Nuclear Information System (INIS)

    Ren, Haijun

    2014-01-01

    Zonal flows (ZFs) in a tokamak plasma with anisotropic pressure are investigated. The dynamics of perpendicular and parallel pressures are determined by the Chew-Goldberger-Low double equations and low-β condition is adopted, where β is the ratio of plasma pressure to the magnetic field pressure. The dispersion relation is analytically derived and illustrates two branches of ZFs. The low frequency zonal flow (LFZF) branch becomes unstable when χ, the ratio of the perpendicular pressure to the parallel one, is greater than a threshold value χ c , which is about 3.8. In the stable region, its frequency increases first and then decreases with increasing χ. For χ = 1, the frequency of LFZF agrees well with the experimental observation. For the instability, the growth rate of LFZF increases with χ. The geodesic acoustic mode branch is shown to be always stable with a frequency increasing with χ. The safety factor is shown to diminish the frequencies of both branches or the growth rate of LFZF

  9. 21 CFR 880.2420 - Electronic monitor for gravity flow infusion systems.

    Science.gov (United States)

    2010-04-01

    ... and Personal Use Monitoring Devices § 880.2420 Electronic monitor for gravity flow infusion systems. (a) Identification. An electronic monitor for gravity flow infusion systems is a device used to... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Electronic monitor for gravity flow infusion...

  10. Note: Real-time monitoring via second-harmonic interferometry of a flow gas cell for laser wakefield acceleration.

    Science.gov (United States)

    Brandi, F; Giammanco, F; Conti, F; Sylla, F; Lambert, G; Gizzi, L A

    2016-08-01

    The use of a gas cell as a target for laser wakefield acceleration (LWFA) offers the possibility to obtain stable and manageable laser-plasma interaction process, a mandatory condition for practical applications of this emerging technique, especially in multi-stage accelerators. In order to obtain full control of the gas particle number density in the interaction region, thus allowing for a long term stable and manageable LWFA, real-time monitoring is necessary. In fact, the ideal gas law cannot be used to estimate the particle density inside the flow cell based on the preset backing pressure and the room temperature because the gas flow depends on several factors like tubing, regulators, and valves in the gas supply system, as well as vacuum chamber volume and vacuum pump speed/throughput. Here, second-harmonic interferometry is applied to measure the particle number density inside a flow gas cell designed for LWFA. The results demonstrate that real-time monitoring is achieved and that using low backing pressure gas (<1 bar) and different cell orifice diameters (<2 mm) it is possible to finely tune the number density up to the 10(19) cm(-3) range well suited for LWFA.

  11. Note: Real-time monitoring via second-harmonic interferometry of a flow gas cell for laser wakefield acceleration

    Energy Technology Data Exchange (ETDEWEB)

    Brandi, F., E-mail: fernando.brandi@ino.it [Intense Laser Irradiation Laboratory (ILIL), Istituto Nazionale di Ottica (INO-CNR), Via Moruzzi 1, 56124 Pisa (Italy); Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163 Genova (Italy); Giammanco, F.; Conti, F. [Dipartimento di Fisica, Università degli Studi di Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Plasma Diagnostics and Technologies Ltd., via Matteucci n.38/D, 56124 Pisa (Italy); Sylla, F. [SourceLAB SAS, 86 Rue de Paris, 91400 Orsay (France); Lambert, G. [LOA, ENSTA ParisTech, CNRS, Ecole Polytechnique, Université Paris-Saclay, 828 bd des Maréchaux, 91762 Palaiseau Cedex (France); Gizzi, L. A. [Intense Laser Irradiation Laboratory (ILIL), Istituto Nazionale di Ottica (INO-CNR), Via Moruzzi 1, 56124 Pisa (Italy)

    2016-08-15

    The use of a gas cell as a target for laser wakefield acceleration (LWFA) offers the possibility to obtain stable and manageable laser-plasma interaction process, a mandatory condition for practical applications of this emerging technique, especially in multi-stage accelerators. In order to obtain full control of the gas particle number density in the interaction region, thus allowing for a long term stable and manageable LWFA, real-time monitoring is necessary. In fact, the ideal gas law cannot be used to estimate the particle density inside the flow cell based on the preset backing pressure and the room temperature because the gas flow depends on several factors like tubing, regulators, and valves in the gas supply system, as well as vacuum chamber volume and vacuum pump speed/throughput. Here, second-harmonic interferometry is applied to measure the particle number density inside a flow gas cell designed for LWFA. The results demonstrate that real-time monitoring is achieved and that using low backing pressure gas (<1 bar) and different cell orifice diameters (<2 mm) it is possible to finely tune the number density up to the 10{sup 19} cm{sup −3} range well suited for LWFA.

  12. Note: Real-time monitoring via second-harmonic interferometry of a flow gas cell for laser wakefield acceleration

    Science.gov (United States)

    Brandi, F.; Giammanco, F.; Conti, F.; Sylla, F.; Lambert, G.; Gizzi, L. A.

    2016-08-01

    The use of a gas cell as a target for laser wakefield acceleration (LWFA) offers the possibility to obtain stable and manageable laser-plasma interaction process, a mandatory condition for practical applications of this emerging technique, especially in multi-stage accelerators. In order to obtain full control of the gas particle number density in the interaction region, thus allowing for a long term stable and manageable LWFA, real-time monitoring is necessary. In fact, the ideal gas law cannot be used to estimate the particle density inside the flow cell based on the preset backing pressure and the room temperature because the gas flow depends on several factors like tubing, regulators, and valves in the gas supply system, as well as vacuum chamber volume and vacuum pump speed/throughput. Here, second-harmonic interferometry is applied to measure the particle number density inside a flow gas cell designed for LWFA. The results demonstrate that real-time monitoring is achieved and that using low backing pressure gas (<1 bar) and different cell orifice diameters (<2 mm) it is possible to finely tune the number density up to the 1019 cm-3 range well suited for LWFA.

  13. Experimental study on low pressure flow instability

    International Nuclear Information System (INIS)

    Jiang Shengyao; Wu Xinxin; Wu Shaorong; Bo Jinhai; Zhang Youjie

    1997-05-01

    The experiment was performed on the test loop (HRTL-5), which simulates the geometry and system design of the 5 MW reactor. The flow behavior for a wide range of inlet subcooling, in which the flow undergoes from single phase to two phase, is described in a natural circulation system at low pressure (p = 0.1, 0.24 MPa). Several kinds of flow instability, e.g. subcooled boiling instability, subcooled boiling induced flashing instability, pure flashing instability as well as flashing coupled density wave instability and high frequency flow oscillation, are investigated. The mechanism of flashing and flashing concerned flow instability, which has never been studied well in this field, is especially interpreted. The experimental results show that, firstly, for a low pressure natural circulation system the two phase flow is unstable in most of inlet subcooling conditions, the two phase stable flow can only be reached at very low inlet subcooling; secondly, at high inlet subcooling the flow instability is dominated by subcooled boiling in the heated section, and at middle inlet subcooling is dominated by void flashing in the adiabatic long riser; thirdly, in two phase stable flow region the condition for boiling out of the core, namely, single phase flow in the heated section, two phase flow in the riser due to vapor flashing, can be realized. The experimental results are very important for the design and accident analysis of the vessel and swimming pool type natural circulation nuclear heating reactor. (7 refs., 10 figs., 1 tab.)

  14. Pressure drop in contraction flow

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz

    This note is a supplement to Dynamic of Polymeric Liquids (DPL) page 178. DPL gives an equation for the pressure drop in a tapered (and circular) contraction, valid only at low angles. Here the general definition of contraction flow (the Bagley correction) and a more general method to find...

  15. Containment pressure monitoring method after severe accident in nuclear power plant

    International Nuclear Information System (INIS)

    Luo Chuanjie; Zhang Shishui

    2011-01-01

    The containment atmosphere monitoring system in nuclear power plant was designed on the basis of design accident. But containment pressure will increase greatly in a severe accident, and pressure instrument in the containment can't satisfy the monitoring requirement. A new method to monitor the pressure change in the containment after a severe accident was considered, through which accident soften methods can be adopted. Under present technical condition, adding a pressure monitoring channel out of containment for post-severe accident is a considerable method. Daya Bay Nuclear Power Plant implemented this modification, by which the containment release time can be delayed during severe accident, and nuclear safety can be increased. After analysis, this method is safe and feasible. (authors)

  16. Storing Data Flow Monitoring in Hadoop

    CERN Document Server

    Georgiou, Anastasia

    2013-01-01

    The on-line data flow monitoring for the CMS data acquisition system produces a large amount of data. Only 5% of data is stored permanently in a relational database due to performance issues and the cost for using dedicated infrastructure (e.g. Oracle systems). In a commercial environment, companies and organizations need to find new innovative approaches to process such big volumes of data, known as “big data”. The Big Data approach is trying to address the problem of a large and complex collection of data sets that become difficult to handle using traditional data processing applications. Using these new technologies, it should be possible to store all the monitoring information for a time window of months or a year. This report contains an initial evaluation of Hadoop for storage of data flow monitoring and subsequent data mining.

  17. Mathematics of flexible risers including pressure and internal flow affects

    Energy Technology Data Exchange (ETDEWEB)

    Seyed, F.B. (John Brown Engineers and Constructors Ltd., London (GB)); Patel, M.H. (University Coll., London (GB). Dept. of Mechanical Engineering)

    1992-01-01

    Derivations are presented for calculation of pressure and internal flow induced forces on flexible risers and other curved pipes using a mathematically rigorous approach. Approximate and exact methods are presented for calculation of pressure forces on straight and curved pipes in two dimensions. The mathematical identity of these equations with those for effective tension is illustrated. The force arising from the flow of an internal fluid of constant density is then calculated and combined with those for pressure forces in derivation of the catenary equations including pressure and internal flow terms. It is shown that internal flow contributes a new term to the expression for effective tension. These governing equations are then reduced for the specific cases of simple catenary, steep-S, lazy-S, steep-wave and lazy-wave risers. In each case, the solution method has been presented and the governing equilibrium and geometric compatability conditions cited. (author).

  18. Batch-processed carbon nanotube wall as pressure and flow sensor

    International Nuclear Information System (INIS)

    Choi, Jungwook; Kim, Jongbaeg

    2010-01-01

    A pressure and flow sensor based on the electrothermal-thermistor effect of a batch-processed carbon nanotube wall (CNT wall) is presented. The negative temperature coefficient of resistance (TCR) of CNTs and the temperature dependent tunneling rate through the CNT/silicon junction enable vacuum pressure and flow velocity sensing because the heat transfer rate between CNTs and the surrounding gas molecules differs depending on pressure and flow rate. The CNT walls are synthesized by thermal chemical vapor deposition (CVD) on an array of microelectrodes fabricated on a silicon-on-insulator (SOI) wafer. The CNTs are self-assembled between the microelectrodes and substrate across the thickness of a buried oxide layer during the synthesis process, and the simple batch fabrication results in high throughput and yield. A wide pressure range, down to 3 x 10 -3 from 10 5 Pa, and a nitrogen flow velocity range between 1 and 52.4 mm s -1 , are sensed. Further experimental characterizations of the bias voltage dependent response of the sensor as a vacuum pressure gauge are presented.

  19. An ultralow power wireless intraocular pressure monitoring system

    International Nuclear Information System (INIS)

    Liu Demeng; Mei Niansong; Zhang Zhaofeng

    2014-01-01

    This paper describes an ultralow power wireless intraocular pressure (IOP) monitoring system that is dedicated to sensing and transferring intraocular pressure of glaucoma patients. Our system is comprised of a capacitive pressure sensor, an application-specific integrated circuit, which is designed on the SMIC 180 nm process, and a dipole antenna. The system is wirelessly powered and demonstrates a power consumption of 7.56 μW at 1.24 V during continuous monitoring, a significant reduction in active power dissipation compared to existing work. The input RF sensitivity is −13 dBm. A significant reduction in input RF sensitivity results from the reduction of mismatch time of the ASK modulation caused by FM0 encoding. The system exhibits an average error of ± 1.5 mmHg in measured pressure. Finally, a complete IOP system is demonstrated in the real biological environment, showing a successful reading of the pressure of an eye. (semiconductor integrated circuits)

  20. Analysis of the pressure fields in a swirling annular jet flow

    Science.gov (United States)

    Percin, M.; Vanierschot, M.; Oudheusden, B. W. van

    2017-12-01

    In this paper, we investigate the flow structures and pressure fields of a free annular swirling jet flow undergoing vortex breakdown. The flow field is analyzed by means of time-resolved tomographic particle image velocimetry measurements, which enable the reconstruction of the three-dimensional time-resolved pressure fields using the governing flow equations. Both time-averaged and instantaneous flow structures are discussed, including a characterization of the first- and second-order statistical moments. A Reynolds decomposition of the flow field shows that the time-averaged flow is axisymmetric with regions of high anisotropic Reynolds stresses. Two recirculation zones exist that are surrounded by regions of very intense mixing. Notwithstanding the axisymmetric nature of the time-averaged flow, a non-axisymmetric structure of the instantaneous flow is revealed, comprising a central vortex core which breaks up into a precessing vortex core. The winding sense of this helical structure is opposite to the swirl direction and it is wrapped around the vortex breakdown bubble. It precesses around the central axis of the flow at a frequency corresponding to a Strouhal number of 0.27. The precessing vortex core is associated with a low-pressure region along the central axis of the jet and the maximum pressure fluctuations occur upstream of the vortex breakdown location, where the azimuthal velocity component also reaches peak values as a result of the inward motion of the fluid and the conservation of angular momentum. The POD analysis of the pressure fields suggests that the precessing helical vortex formation is the dominant coherent structure in the instantaneous flow.

  1. CFD simulation of subcooled flow boiling at low pressure

    International Nuclear Information System (INIS)

    Koncar, B.; Mavko, B.

    2001-01-01

    An increased interest to numerically simulate the subcooled flow boiling at low pressures (1 to 10 bar) has been aroused in recent years, pursued by the need to perform safety analyses of research nuclear reactors and to investigate the sump cooling concept for future light water reactors. In this paper the subcooled flow boiling has been simulated with a multidimensional two-fluid model used in a CFX-4.3 computational fluid dynamics (CFD) code. The existing model was adequately modified for low pressure conditions. It was shown that interfacial forces, which are usually used for adiabatic flows, need to be modeled to simulate subcooled boiling at low pressure conditions. Simulation results are compared against published experimental data [1] and agree well with experiments.(author)

  2. Monitoring And Controlling Hydroponic Flow

    Science.gov (United States)

    Dreschel, Thomas W.

    1992-01-01

    Pressure-monitoring and -controlling apparatus maintains slight suction required on nutrient solution in apparatus described in "Tubular Membrane Plant-Growth Unit" (KSC-11375), while overcoming gravity effects on operation of system on Earth. Suction helps to hold solution in tubular membrane.

  3. Experimental and computational analysis of pressure response in a multiphase flow loop

    Science.gov (United States)

    Morshed, Munzarin; Amin, Al; Rahman, Mohammad Azizur; Imtiaz, Syed

    2016-07-01

    The characteristics of multiphase fluid flow in pipes are useful to understand fluid mechanics encountered in the oil and gas industries. In the present day oil and gas exploration is successively inducing subsea operation in the deep sea and arctic condition. During the transport of petroleum products, understanding the fluid dynamics inside the pipe network is important for flow assurance. In this case the information regarding static and dynamic pressure response, pressure loss, optimum flow rate, pipe diameter etc. are the important parameter for flow assurance. The principal aim of this research is to represents computational analysis and experimental analysis of multi-phase (L/G) in a pipe network. This computational study considers a two-phase fluid flow through a horizontal flow loop with at different Reynolds number in order to determine the pressure distribution, frictional pressure loss profiles by volume of fluid (VOF) method. However, numerical simulations are validated with the experimental data. The experiment is conducted in 76.20 mm ID transparent circular pipe using water and air in the flow loop. Static pressure transducers are used to measure local pressure response in multiphase pipeline.

  4. AUTOMATED TECHNIQUE FOR FLOW MEASUREMENTS FROM MARIOTTE RESERVOIRS.

    Science.gov (United States)

    Constantz, Jim; Murphy, Fred

    1987-01-01

    The mariotte reservoir supplies water at a constant hydraulic pressure by self-regulation of its internal gas pressure. Automated outflow measurements from mariotte reservoirs are generally difficult because of the reservoir's self-regulation mechanism. This paper describes an automated flow meter specifically designed for use with mariotte reservoirs. The flow meter monitors changes in the mariotte reservoir's gas pressure during outflow to determine changes in the reservoir's water level. The flow measurement is performed by attaching a pressure transducer to the top of a mariotte reservoir and monitoring gas pressure changes during outflow with a programmable data logger. The advantages of the new automated flow measurement techniques include: (i) the ability to rapidly record a large range of fluxes without restricting outflow, and (ii) the ability to accurately average the pulsing flow, which commonly occurs during outflow from the mariotte reservoir.

  5. FEMO, A FLOW AND ENRICHMENT MONITOR FOR VERIFYING COMPLIANCE WITH INTERNATIONAL SAFEGUARDS REQUIREMENTS AT A GAS CENTRIFUGE ENRICHMENT FACILITY

    International Nuclear Information System (INIS)

    Gunning, John E.; Laughter, Mark D.; March-Leuba, Jose A.

    2008-01-01

    A number of countries have received construction licenses or are contemplating the construction of large-capacity gas centrifuge enrichment plants (GCEPs). The capability to independently verify nuclear material flows is a key component of international safeguards approaches, and the IAEA does not currently have an approved method to continuously monitor the mass flow of 235U in uranium hexafluoride (UF6) gas streams. Oak Ridge National Laboratory is investigating the development of a flow and enrichment monitor, or FEMO, based on an existing blend-down monitoring system (BDMS). The BDMS was designed to continuously monitor both 235U mass flow and enrichment of UF6 streams at the low pressures similar to those which exists at GCEPs. BDMSs have been installed at three sites-the first unit has operated successfully in an unattended environment for approximately 10 years. To be acceptable to GCEP operators, it is essential that the instrument be installed and maintained without interrupting operations. A means to continuously verify flow as is proposed by FEMO will likely be needed to monitor safeguards at large-capacity plants. This will enable the safeguards effectiveness that currently exists at smaller plants to be maintained at the larger facilities and also has the potential to reduce labor costs associated with inspections at current and future plants. This paper describes the FEMO design requirements, operating capabilities, and development work required before field demonstration.

  6. Cuff inflation during ambulatory blood pressure monitoring and heart rate

    Directory of Open Access Journals (Sweden)

    Mia Skov-Madsen

    2008-11-01

    Full Text Available Mia Skov-Madsen, My Svensson, Jeppe Hagstrup ChristensenDepartment of Nephrology, Aarhus University Hospital, Aalborg, DenmarkIntroduction: Twenty four-hour ambulatory blood pressure monitoring is a clinically validated procedure in evaluation of blood pressure (BP. We hypothesised that the discomfort during cuff inflation would increase the heart rate (HR measured with 24-h ambulatory BP monitoring compared to a following HR measurement with a 24-h Holter monitor.Methods: The study population (n = 56 were recruited from the outpatient’s clinic at the Department of Nephrology, Aalborg Hospital, Aarhus University Hospital at Aalborg, Denmark. All the patients had chronic kidney disease (CKD. We compared HR measured with a 24-h Holter monitor with a following HR measured by a 24-h ambulatory BP monitoring.Results: We found a highly significant correlation between the HR measured with the Holter monitor and HR measured with 24-h ambulatory blood pressure monitoring (r = 0.77, p < 0.001. Using the Bland-Altman plot, the mean difference in HR was only 0.5 beat/min during 24 hours with acceptable limits of agreement for both high and low HR levels. Dividing the patients into groups according to betablocker treatment, body mass index, age, sex, angiotensin-converting enzyme inhibitor treatment, statins treatment, diuretic treatment, or calcium channel blocker treatment revealed similar results as described above.Conclusion: The results indicate that the discomfort induced by cuff inflation during 24-h ambulatory BP monitoring does not increase HR. Thus, 24-h ambulatory BP monitoring may be a reliable measurement of the BP among people with CKD.Keywords: ambulatory blood pressure monitoring, Holter monitoring, heart rate, chronic kidney disease, hypertension

  7. Transpiring purging access probe for particulate laden or hazardous environments

    Science.gov (United States)

    VanOsdol, John G

    2013-12-03

    An access probe for remote-sensing access through a viewing port, viewing volume, and access port into a vessel. The physical boundary around the viewing volume is partially formed by a porous sleeve lying between the viewing volume and a fluid conduit. In a first mode of operation, a fluid supplied to the fluid conduit encounters the porous sleeve and flows through the porous material to maintain the viewing volume free of ash or other matter. When additional fluid force is needed to clear the viewing volume, the pressure of the fluid flow is increased sufficiently to slidably translate the porous sleeve, greatly increasing the flow into the viewing volume. The porous sleeve is returned to position by an actuating spring. The access probe thereby provides for alternate modes of operation based on the pressure of an actuating fluid.

  8. Flow Field Measurements of Methane-Oxygen Turbulent Nonpremixed Flames at High Pressure

    Science.gov (United States)

    Iino, Kimio; Kikkawa, Hoshitaka; Akamatsu, Fumiteru; Katsuki, Masashi

    We carried out the flow field measurement of methane-oxygen turbulent nonpremixed flame in non-combusting and combusting situations at high pressures using LDV. The main objectives are to study the influences of combustion on the turbulence structure at high pressures and to provide detailed data on which numerical predictions on such flows can rely. Direct observation and CH* chemiluminescence detection are conducted at high pressures up to 1.0MPa. It was found that the flame length at elevated pressures became constant. From flow field measurements, the following features of flames at elevated pressure were found: (1) the existence of flame suppressed turbulence in the upstream region of the jet and enhanced it in the downstream region with increasing pressure; (2) Turbulence in the flame was more anisotropic than in the corresponding cold jet in all regions of the flow with increasing pressure; (3) Reynolds shear stresses did not change at elevated pressure; (4) Combustion processes had a marked influence on the turbulence macroscale under high pressures, however, the turbulence macroscale was not changed even with the increase in pressure.

  9. Pressure-sensitive paint on a truncated cone in hypersonic flow at incidences

    International Nuclear Information System (INIS)

    Yang, L.; Erdem, E.; Zare-Behtash, H.; Kontis, K.; Saravanan, S.

    2012-01-01

    Highlights: ► Global pressure map over the truncated cone is obtained at various incidence angles in Mach 5 flow. ► Successful application of AA-PSP in hypersonic flow expands operation area of this technique. ► AA-PSP reveals complex three-dimensional pattern which is difficult for transducer to obtain. ► Quantitative data provides strong correlation with colour Schlieren and oil flow results. ► High spatial resolution pressure mappings identify small scale vortices and flow separation. - Abstract: The flow over a truncated cone is a classical and fundamental problem for aerodynamic research due to its three-dimensional and complicated characteristics. The flow is made more complex when examining high angles of incidence. Recently these types of flows have drawn more attention for the purposes of drag reduction in supersonic/hypersonic flows. In the present study the flow over a truncated cone at various incidences was experimentally investigated in a Mach 5 flow with a unit Reynolds number of 13.5 × 10 6 m −1 . The cone semi-apex angle is 15° and the truncation ratio (truncated length/cone length) is 0.5. The incidence of the model varied from −12° to 12° with 3° intervals relative to the freestream direction. The external flow around the truncated cone was visualised by colour Schlieren photography, while the surface flow pattern was revealed using the oil flow method. The surface pressure distribution was measured using the anodized aluminium pressure-sensitive paint (AA-PSP) technique. Both top and sideviews of the pressure distribution on the model surface were acquired at various incidences. AA-PSP showed high pressure sensitivity and captured the complicated flow structures which correlated well with the colour Schlieren and oil flow visualisation results.

  10. Conformable amplified lead zirconate titanate sensors with enhanced piezoelectric response for cutaneous pressure monitoring.

    Science.gov (United States)

    Dagdeviren, Canan; Su, Yewang; Joe, Pauline; Yona, Raissa; Liu, Yuhao; Kim, Yun-Soung; Huang, YongAn; Damadoran, Anoop R; Xia, Jing; Martin, Lane W; Huang, Yonggang; Rogers, John A

    2014-08-05

    The ability to measure subtle changes in arterial pressure using devices mounted on the skin can be valuable for monitoring vital signs in emergency care, detecting the early onset of cardiovascular disease and continuously assessing health status. Conventional technologies are well suited for use in traditional clinical settings, but cannot be easily adapted for sustained use during daily activities. Here we introduce a conformal device that avoids these limitations. Ultrathin inorganic piezoelectric and semiconductor materials on elastomer substrates enable amplified, low hysteresis measurements of pressure on the skin, with high levels of sensitivity (~0.005 Pa) and fast response times (~0.1 ms). Experimental and theoretical studies reveal enhanced piezoelectric responses in lead zirconate titanate that follow from integration on soft supports as well as engineering behaviours of the associated devices. Calibrated measurements of pressure variations of blood flow in near-surface arteries demonstrate capabilities for measuring radial artery augmentation index and pulse pressure velocity.

  11. Comparison of differential pressure model based on flow regime for gas/liquid two-phase flow

    International Nuclear Information System (INIS)

    Dong, F; Zhang, F S; Li, W; Tan, C

    2009-01-01

    Gas/liquid two-phase flow in horizontal pipe is very common in many industry processes, because of the complexity and variability, the real-time parameter measurement of two-phase flow, such as the measurement of flow regime and flow rate, becomes a difficult issue in the field of engineering and science. The flow regime recognition plays a fundamental role in gas/liquid two-phase flow measurement, other parameters of two-phase flow can be measured more easily and correctly based on the correct flow regime recognition result. A multi-sensor system is introduced to make the flow regime recognition and the mass flow rate measurement. The fusion system is consisted of temperature sensor, pressure sensor, cross-section information system and v-cone flow meter. After the flow regime recognition by cross-section information system, comparison of four typical differential pressure (DP) models is discussed based on the DP signal of v-cone flow meter. Eventually, an optimum DP model has been chosen for each flow regime. The experiment result of mass flow rate measurement shows it is efficient to classify the DP models by flow regime.

  12. Choking under monitoring pressure: being watched by the experimenter reduces executive attention.

    Science.gov (United States)

    Belletier, Clément; Davranche, Karen; Tellier, Idriss S; Dumas, Florence; Vidal, Franck; Hasbroucq, Thierry; Huguet, Pascal

    2015-10-01

    Performing more poorly given one's skill level ("choking") is likely in situations that offer an incentive if a certain outcome is achieved (outcome pressure) or when one is being watched by others-especially when one's performance is being evaluated (monitoring pressure). According to the choking literature, outcome pressure is associated with reduced executive control of attention, whereas monitoring pressure is associated with increased, yet counterproductive, attention to skill processes. Here, we show the first evidence that monitoring pressure-being watched by the experimenter-may lead individuals with higher working memory to choke on a classic measure of executive control-just the task effect thought to result from outcome pressure. Not only does this finding help refine our understanding of the processes underlying choking under monitoring pressure, but it also leads to a new look at classic audience effects, with an important implication for experimental psychology.

  13. Pressure-flow characteristics of normal and disordered esophageal motor patterns.

    Science.gov (United States)

    Singendonk, Maartje M J; Kritas, Stamatiki; Cock, Charles; Ferris, Lara F; McCall, Lisa; Rommel, Nathalie; van Wijk, Michiel P; Benninga, Marc A; Moore, David; Omari, Taher I

    2015-03-01

    To perform pressure-flow analysis (PFA) in a cohort of pediatric patients who were referred for diagnostic manometric investigation. PFA was performed using purpose designed Matlab-based software. The pressure-flow index (PFI), a composite measure of bolus pressurization relative to flow and the impedance ratio, a measure of the extent of bolus clearance failure were calculated. Tracings of 76 pediatric patients (32 males; 9.1 ± 0.7 years) and 25 healthy adult controls (7 males; 36.1 ± 2.2 years) were analyzed. Patients mostly had normal motility (50%) or a category 4 disorder and usually weak peristalsis (31.5%) according to the Chicago Classification. PFA of healthy controls defined reference ranges for PFI ≤142 and impedance ratio ≤0.49. Pediatric patients with pressure-flow (PF) characteristics within these limits had normal motility (62%), most patients with PF characteristics outside these limits also had an abnormal Chicago Classification (61%). Patients with high PFI and disordered motor patterns all had esophagogastric junction outflow obstruction. Disordered PF characteristics are associated with disordered esophageal motor patterns. By defining the degree of over-pressurization and/or extent of clearance failure, PFA may be a useful adjunct to esophageal pressure topography-based classification. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. The effects of DDoS attacks on flow monitoring applications

    NARCIS (Netherlands)

    Sadre, R.; Sperotto, Anna; Pras, Aiko

    Flow-based monitoring has become a popular approach in many areas of network management. However, flow monitoring is, by design, susceptible to anomalies that generate a large number of flows, such as Distributed Denial-Of-Service attacks. This paper aims at getting a better understanding on how a

  15. Depth-dependent flow and pressure characteristics in cortical microvascular networks.

    Directory of Open Access Journals (Sweden)

    Franca Schmid

    2017-02-01

    Full Text Available A better knowledge of the flow and pressure distribution in realistic microvascular networks is needed for improving our understanding of neurovascular coupling mechanisms and the related measurement techniques. Here, numerical simulations with discrete tracking of red blood cells (RBCs are performed in three realistic microvascular networks from the mouse cerebral cortex. Our analysis is based on trajectories of individual RBCs and focuses on layer-specific flow phenomena until a cortical depth of 1 mm. The individual RBC trajectories reveal that in the capillary bed RBCs preferentially move in plane. Hence, the capillary flow field shows laminar patterns and a layer-specific analysis is valid. We demonstrate that for RBCs entering the capillary bed close to the cortical surface (< 400 μm the largest pressure drop takes place in the capillaries (37%, while for deeper regions arterioles are responsible for 61% of the total pressure drop. Further flow characteristics, such as capillary transit time or RBC velocity, also vary significantly over cortical depth. Comparison of purely topological characteristics with flow-based ones shows that a combined interpretation of topology and flow is indispensable. Our results provide evidence that it is crucial to consider layer-specific differences for all investigations related to the flow and pressure distribution in the cortical vasculature. These findings support the hypothesis that for an efficient oxygen up-regulation at least two regulation mechanisms must be playing hand in hand, namely cerebral blood flow increase and microvascular flow homogenization. However, the contribution of both regulation mechanisms to oxygen up-regulation likely varies over depth.

  16. Efficient Unsteady Flow Visualization with High-Order Access Dependencies

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Jiang; Guo, Hanqi; Yuan, Xiaoru

    2016-04-19

    We present a novel high-order access dependencies based model for efficient pathline computation in unsteady flow visualization. By taking longer access sequences into account to model more sophisticated data access patterns in particle tracing, our method greatly improves the accuracy and reliability in data access prediction. In our work, high-order access dependencies are calculated by tracing uniformly-seeded pathlines in both forward and backward directions in a preprocessing stage. The effectiveness of our proposed approach is demonstrated through a parallel particle tracing framework with high-order data prefetching. Results show that our method achieves higher data locality and hence improves the efficiency of pathline computation.

  17. Assessing complexity of skin blood flow oscillations in response to locally applied heating and pressure in rats: Implications for pressure ulcer risk

    Science.gov (United States)

    Liao, Fuyuan; O'Brien, William D.; Jan, Yih-Kuen

    2013-10-01

    The objective of this study was to investigate the effects of local heating on the complexity of skin blood flow oscillations (BFO) under prolonged surface pressure in rats. Eleven Sprague-Dawley rats were studied: 7 rats underwent surface pressure with local heating (△t=10 °C) and 4 rats underwent pressure without heating. A pressure of 700 mmHg was applied to the right trochanter area of rats for 3 h. Skin blood flow was measured using laser Doppler flowmetry. The loading period was divided into nonoverlapping 30 min epochs. For each epoch, multifractal detrended fluctuation analysis (MDFA) was utilized to compute DFA coefficients and complexity of endothelial related metabolic, neurogenic, and myogenic frequencies of BFO. The results showed that under surface pressure, local heating led to a significant decrease in DFA coefficients of myogenic frequency during the initial epoch of loading period, a sustained decrease in complexity of myogenic frequency, and a significantly higher degree of complexity of metabolic frequency during the later phase of loading period. Surrogate tests showed that the reduction in complexity of myogenic frequency was associated with a loss of nonlinearity whereas increased complexity of metabolic frequency was associated with enhanced nonlinearity. Our results indicate that increased metabolic activity and decreased myogenic response due to local heating manifest themselves not only in magnitudes of metabolic and myogenic frequencies but also in their structural complexity. This study demonstrates the feasibility of using complexity analysis of BFO to monitor the ischemic status of weight-bearing skin and risk of pressure ulcers.

  18. The calibration of a cylindrical pressure probe for recirculating flow measurements

    International Nuclear Information System (INIS)

    Lawn, C.J.

    1975-06-01

    The use of the pressure distribution around a cylinder in cross-flow to indicate the magnitude and direction of the velocity vector is discussed in the context of making measurements in highly turbulent recirculating flows. The intended application is the measurement of the flow between the ribs on the large-scale model of the AGR fuel-pin surface. Results from a number of calibration experiments in boundary layers are used to provide a correlation for the positions at which local static pressure is measured on the cylinder surface. After appropriate corrections, the dynamic pressure is deduced from the pressure at the stagnation point. Corrections are also necessary in deducing the direction of flow from the bisector of the static pressure positions, when the cylinder is in a shear flow or near a wall, and these too are evaluated from the results of the calibration experiments. Measurements in two recirculating flows are then presented as an illustration both of the validity and limitations of the technique. In the first case, comparison is made with the measurements of a pulsed-wire anemometer behind a surface-mounted cube and, in the second, the continuity is used to provide an overall check on measurements behind a transverse plate. It is concluded that useful results can be obtained in many turbulent flow situations. (author)

  19. Experimental Studies of Low-Pressure Turbine Flows and Flow Control. Streamwise Pressure Profiles and Velocity Profiles

    Science.gov (United States)

    Volino, Ralph

    2012-01-01

    This report summarizes research performed in support of the NASA Glenn Research Center (GRC) Low-Pressure Turbine (LPT) Flow Physics Program. The work was performed experimentally at the U.S. Naval Academy faculties. The geometry corresponded to "Pak B" LPT airfoil. The test section simulated LPT flow in a passage. Three experimental studies were performed: (a) Boundary layer measurements for ten baseline cases under high and low freestream turbulence conditions at five Reynolds numbers of 25,000, 50,000, 100,000, 200,000, and 300,000, based on passage exit velocity and suction surface wetted length; (b) Passive flow control studies with three thicknesses of two-dimensional bars, and two heights of three-dimensional circular cylinders with different spanwise separations, at same flow conditions as the 10 baseline cases; (c) Active flow control with oscillating synthetic (zero net mass flow) vortex generator jets, for one case with low freestream turbulence and a low Reynolds number of 25,000. The Passive flow control was successful at controlling the separation problem at low Reynolds numbers, with varying degrees of success from case to case and varying levels of impact at higher Reynolds numbers. The active flow control successfully eliminated the large separation problem for the low Reynolds number case. Very detailed data was acquired using hot-wire anemometry, including single and two velocity components, integral boundary layer quantities, turbulence statistics and spectra, turbulent shear stresses and their spectra, and intermittency, documenting transition, separation and reattachment. Models were constructed to correlate the results. The report includes a summary of the work performed and reprints of the publications describing the various studies.This report summarizes research performed in support of the NASA Glenn Research Center (GRC) Low-Pressure Turbine (LPT) Flow Physics Program. The work was performed experimentally at the U.S. Naval Academy

  20. A total pressure-saturation formulation of two-phase flow incorporating dynamic effects in the capillary-pressure-saturation relationship

    Energy Technology Data Exchange (ETDEWEB)

    Dahle, H K; Celia, M A; Hassanizadeh, S M; Karlsen, K H

    2002-07-01

    New theories suggest that the relationship between capillary pressure and saturation should be enhanced by a dynamic term that is proportional to the time rate of change of saturation. This so-called dynamic capillary pressure formulation is supported by laboratory experiments, and can be included in various forms of the governing equations for two-phase flow in porous media. An extended model of two-phase flow in porous media may be developed based on fractional flow curves and a total pressure - saturation description that includes the dynamic capillary pressure terms. A dimensionless form of the resulting equation set provides an ideal tool to study the relative importance of the dynamic capillary pressure effect. This equation provides a rich set of mathematical research questions, and numerical solutions to the equation provide insights into the behavior of two-phase immiscible flow. For typical two-phase flow systems, dynamic capillary pressure acts to retard infiltration fronts, with responses dependent on system parameters including boundary conditions. Recent theoretical work suggests that the traditional algebraic relationship between capillary pressure and saturation may be inadequate. Instead, a so-called dynamic capillary pressure formulation is needed, where capillary pressure is defined as a thermodynamic variable, and the difference between phase pressures is only equal to the capillary pressure at equilibrium. Under dynamic conditions, the disequilibrium between phase-pressure differences and the capillary pressure is taken to be proportional to the time rate of change of saturation. A recent study by Hassanizadeh et al. presents experimental evidence, culled from the literature, to support this claim. Numerical simulations using dynamic pore-scale network models and upscaling also support the claim. Hassanizadeh et al. also presented numerical solutions for an enhanced version of Richards' equation that included the dynamic terms. A preliminary

  1. Experimental investigation on flow patterns of RP-3 kerosene under sub-critical and supercritical pressures

    Science.gov (United States)

    Wang, Ning; Zhou, Jin; Pan, Yu; Wang, Hui

    2014-02-01

    Active cooling with endothermic hydrocarbon fuel is proved to be one of the most promising approaches to solve the thermal problem for hypersonic aircraft such as scramjet. The flow patterns of two-phase flow inside the cooling channels have a great influence on the heat transfer characteristics. In this study, phase transition processes of RP-3 kerosene flowing inside a square quartz-glass tube were experimentally investigated. Three distinct phase transition phenomena (liquid-gas two phase flow under sub-critical pressures, critical opalescence under critical pressure, and corrugation under supercritical pressures) were identified. The conventional flow patterns of liquid-gas two phase flow, namely bubble flow, slug flow, churn flow and annular flow are observed under sub-critical pressures. Dense bubble flow and dispersed flow are recognized when pressure is increased towards the critical pressure whilst slug flow, churn flow and annular flow disappear. Under critical pressure, the opalescence phenomenon is observed. Under supercritical pressures, no conventional phase transition characteristics, such as bubbles are observed. But some kind of corrugation appears when RP-3 transfers from liquid to supercritical. The refraction index variation caused by sharp density gradient near the critical temperature is thought to be responsible for this corrugation.

  2. Analysis of flow induced valve operation and pressure wave propagation for single and two-phase flow conditions

    International Nuclear Information System (INIS)

    Nagel, H.

    1986-01-01

    The flow induced valve operation is calculated for single and two-phase flow conditions by the fluid dynamic computer code DYVRO and results are compared to experimental data. The analysis show that the operational behaviour of the valves is not only dependent on the condition of the induced flow, but also the pipe flow can cause a feedback as a result of the induced pressure waves. For the calculation of pressure wave propagation in pipes of which the operation of flow induced valves has a considerable influence it is therefore necessary to have a coupled analysis of the pressure wave propagation and the operational behaviour of the valves. The analyses of the fast transient transfer from steam to two-phase flow show a good agreement with experimental data. Hence even these very high loads on pipes resulting from such fluid dynamic transients can be calculated realistically. (orig.)

  3. Data describing the flow-mediated vasodilation responses and blood pressure in young adult humans after a single dose of oral edible emu oil

    Directory of Open Access Journals (Sweden)

    Tadayoshi Miyashita

    2018-04-01

    Full Text Available The data provided herein include flow-mediated vasodilation responses, represented by changes in arterial diameter, and blood pressure in young adults after a single oral dose of edible emu oil or placebo (cross-over design. Ten healthy men and 10 healthy women participated. Increased blood flow in the antebrachial region was induced by inflating a pressure cuff and subsequently releasing the pressure by deflating the cuff. After the release, the arterial diameter was continuously monitored for 110 sec using ultrasonic diagnostic equipment. The changes in the arterial diameter from 20 to 110 sec post-cuff deflation are described in line graphs and tables. In addition, systolic and diastolic blood pressure data are provided in a table.

  4. Physiologic Pressure and Flow Changes During Parabolic Flight (Pilot Study)

    Science.gov (United States)

    Pantalos, George; Sharp, M. Keith; Mathias, John R.; Hargens, Alan R.; Watenpaugh, Donald E.; Buckey, Jay C.

    1999-01-01

    The objective of this study was to obtain measurement of cutaneous tissue perfusion central and peripheral venous pressure, and esophageal and abdominal pressure in human test subjects during parabolic flight. Hemodynamic data recorded during SLS-I and SLS-2 missions have resulted in the paradoxical finding of increased cardiac stroke volume in the presence of a decreased central venous pressure (CVP) following entry in weightlessness. The investigators have proposed that in the absence of gravity, acceleration-induced peripheral vascular compression is relieved, increasing peripheral vascular capacity and flow while reducing central and peripheral venous pressure, This pilot study seeks to measure blood pressure and flow in human test subjects during parabolic flight for different postures.

  5. Method and device for measuring fluid flow

    International Nuclear Information System (INIS)

    Atherton, R.; Marinkovich, P.S.; Spadaro, P.R.; Stout, J.W.

    1976-01-01

    The invention is a fluid flow measuring device for determining the coolant flow at the entrance to a specific nuclear reactor fuel region. The device comprises a plurality of venturis having the upstream inlet and throat pressure of each respectively manifolded together to provide one static pressure signal for each region monitored. The device provides accurate flow measurement with low pressure losses and uniform entrance and discharge flow distribution. 1 claim, 7 figures

  6. Flow Monitoring Experiences at the Ethernet-Layer

    NARCIS (Netherlands)

    Hofstede, Rick; Hofstede, R.J.; Drago, Idilio; Sperotto, Anna; Pras, Aiko; Lehnert, Ralf

    2011-01-01

    Flow monitoring is a scalable technology for providing summaries of network activity. Being deployed at the IP-layer, it uses fixed flow definitions, based on fields of the IP-layer and higher layers. Since several backbone network operators are considering the deployment of (Carrier) Ethernet in

  7. Using PIV to determine relative pressures in a stenotic phantom under steady flow based on the pressure-poisson equation.

    Science.gov (United States)

    Khodarahmi, Iman; Shakeri, Mostafa; Sharp, M; Amini, Amir A

    2010-01-01

    Pressure gradient across a Gaussian-shaped 87% area stenosis phantom was estimated by solving the pressure Poisson equation (PPE) for a steady flow mimicking the blood flow through the human iliac artery. The velocity field needed to solve the pressure equation was obtained using particle image velocimetry (PIV). A steady flow rate of 46.9 ml/s was used, which corresponds to a Reynolds number of 188 and 595 at the inlet and stenosis throat, respectively (in the range of mean Reynolds number encountered in-vivo). In addition, computational fluid dynamics (CFD) simulation of the same flow was performed. Pressure drops across the stenosis predicted by PPE/PIV and CFD were compared with those measured by a pressure catheter transducer. RMS errors relative to the measurements were 17% and 10% for PPE/PIV and CFD, respectively.

  8. Validation of the HONSUN LD-578 blood pressure monitor for home blood pressure monitoring according to the European Society of Hypertension International Protocol.

    Science.gov (United States)

    Zhang, Yi; Wang, Jie; Huang, Qi-Fang; Sheng, Chang-Sheng; Li, Yan; Wang, Ji-Guang

    2009-06-01

    This study aimed to evaluate the accuracy of the automated oscillometric upper arm blood pressure monitor LD-578 (HONSUN Group, Shanghai, China) for home blood pressure monitoring according to the International Protocol. Systolic and diastolic blood pressures were sequentially measured in 33 adult Chinese using a mercury sphygmomanometer (two observers) and the LD-578 device (one supervisor). Ninety-nine pairs of comparisons were obtained from 15 participants in phase 1 and a further 18 participants in phase 2 of the validation study. Data analysis was performed using the ESHIP Analyzer. The LD-578 device successfully passed phase 1 of the validation study with a number of absolute differences between device and observers within 5, 10, and 15 mmHg for at least 32 of 45, 41 of 45, and 45 of 45 measurements (required 25, 35, and 40), respectively. The device also achieved the targets for phase 2.1, with 67 of 99, 90 of 99, and 98 of 99 differences within 5, 10, and 15 mmHg, respectively, for systolic blood pressure, and with 69 of 99, 95 of 99, and 98 of 99 within 5, 10, and 15 mmHg, respectively, for diastolic blood pressure. In phase 2.2, 24 participants had at least two of the three device-observers differences within 5 mmHg (required >or=22) for systolic and diastolic blood pressure. The HONSUN upper arm blood pressure monitor LD-578 can be recommended for home use in adults.

  9. Pressure pulsation measurements in pipe and cluster flows

    International Nuclear Information System (INIS)

    Benemann, A.; Voj, P.

    1976-01-01

    Measuring and evaluation techniques of pressure pulsations in pipe and cluster flows are described. The measurements were made on a 1 m long SNR rod-cluster and its feed and drain pipes. At Reynolds numbers in the cluster of 8.9 x 10 4 flow velocities of 14 m/sec were achieved. With the aid of a block diagram recording of the measured values by piezoelectric crystal and piezo-resistive strain gange as well as data processing are explained. For the analytical treatment of the pressure pulsation signals characterizing the turbulence field computer codes of a digital computer and a fast-fourier analyzer (Hewlett-Packard 5450 A) were used. The results show good agreement with theoretical curves on the behaviour of turbulent boundary layers of cluster and pipe flows at high Reynolds numbers. (TK) [de

  10. [A design and study of a novel electronic device for cuff-pressure monitoring].

    Science.gov (United States)

    Wang, Shupeng; Li, Wei; Li, Wen; Song, Dejing; Chen, Desheng; Duan, Jun; Li, Chen; Li, Gang

    2017-06-01

    To design a novel electronic device for measuring the pressure in the cuff of the artificial airway; and to study the advantage of this device on continuous and intermittent cuff pressure monitoring. (1) a portable electronic device for cuff pressure measurement was invented, which could turn pressure signal into electrical signal through a pressure transducer. Meantime, it was possible to avoid pressure leak from the joint and the inside of the apparatus by modified Luer taper and sophisticated design. If the cuff pressure was out of the normal range, the apparatus could release a sound and light alarm. (2) Six traditional mechanical manometers were used to determine the cuff pressure in 6 tracheal tubes. The cuff pressure was maintain at 30 cmH 2 O (1 cmH 2 O = 0.098 kPa) by the manometer first, and repeated every 30 seconds for 4 times. (3) Study of continuous cuff pressure monitoring: We used a random number generator to randomize 6 tracheal tubes, 6 mechanical manometers and 6 our products by number 1-6, which has the same number of a group. Every group was further randomized into two balanced groups, one group used the mechanical manometer first, and the other used our product first. The baseline pressure was 30 cmH 2 O, measurement was performed every 4 hours for 6 times. When traditional mechanical manometer was used for cuff pressure monitoring, cuff pressure was decreased by an average of 2.9 cmH 2 O for each measurement (F = 728.2, P = 0.000). In study of continually monitoring, at each monitoring point, the pressure measured by electronic manometer was higher than the mechanical manometer. All the pressures measured by mechanical manometer were dropped below 20 cmH 2 O at 8th hour, and there was no pressure decrease below 20 cmH 2 O measured by electronic manometer in 24 hours by contrast. In study of intermittent monitoring, the same result was found. The pressure was dropped significantly with time when measured by mechanical manometer (F = 61.795, P

  11. Hardware implementation of the ORNL fissile mass flow monitor

    International Nuclear Information System (INIS)

    McEvers, J.; Sumner, J.; Jones, R.; Ferrell, R.; Martin, C.; Uckan, T.; March-Leuba, J.

    1998-01-01

    This paper provides an overall description of the implementation of the Oak Ridge National Laboratory (ORNL) Fissile Mass Flow Monitor, which is part of a Blend Down Monitoring System (BDMS) developed by the US Department of Energy (DOE). The Fissile Mass Flow Monitor is designed to measure the mass flow of fissile material through a gaseous or liquid process stream. It consists of a source-modulator assembly, a detector assembly, and a cabinet that houses all control, data acquisition, and supporting electronics equipment. The development of this flow monitor was first funded by DOE/NE in September 95, and an initial demonstration by ORNL was described in previous INMM meetings. This methodology was chosen by DOE/NE for implementation in November 1996, and the hardware/software development is complete. Successful BDMS installation and operation of the complete BDMS has been demonstrated in the Paducah Gaseous Diffusion Plant (PGDP), which is operated by Lockheed Martin Utility Services, Inc. for the US Enrichment Corporation and regulated by the Nuclear Regulatory Commission. Equipment for two BDMS units has been shipped to the Russian Federation

  12. Design of safety monitor system for operation sintering furnace ME-06

    International Nuclear Information System (INIS)

    Sugeng Rianto; Triarjo; Djoko Kisworo; Agus Sartono

    2013-01-01

    Design of safety monitoring system for safety operation of sinter furnace ME-06 has been done. Parameters monitored during this operation include: temperature, gas pressure, flow rate of gas, voltage and current furnace. For sintering furnace temperature system that monitored were the temperature of the furnace temperature, the temperature of the cooling water system inlet and outlet, temperature of flow hydrogen gas inlet and outlet. For pressure system and flow rate gas sinter furnace which monitored the pressure and flow rate of hydrogen gas inlet and outlet. The system also monitors current and voltage applied to the sinter furnace heating system. Monitor system hardware consists of: the system temperature sensor, pressure, rate and data acquisition systems. While software systems using the labview driver interface that connects the hard and software systems. Function test results during sintering operation for setting the temperature 1700 °C sintering temperature increases the ramp function by 250 °C/hour average measurements obtained when the sintering time 1707.016 °C with a standard deviation of 0.38 °C. The maximum temperature of the hydrogen gas temperature 35.4 °C. The maximum temperature of the cooling water system 27.4 °C. The maximum pressure of 1,911 bar Gas Inlet and outlet of 0,051 bar. Maximum inlet gas flow 12.996 L / min and outlet 14.086 L / min. (author)

  13. Telemetric implantable pressure sensor for short- and long-term monitoring of intracranial pressure.

    Science.gov (United States)

    Frischholz, M; Sarmento, L; Wenzel, M; Aquilina, K; Edwards, R; Coakham, H B

    2007-01-01

    Patients with hydrocephalus, idiopathic intracranial hypertension and head injury frequently require monitoring of intracranial pressure (ICP) and may need repeated episodes of monitoring months or years apart. The gold standard for measurement of ICP remains the external ventricular catheter. This is a fluid-filled catheter transducer system that allows regular recalibration and correction of zero drift by its position relative to a fixed anatomical reference. It also allows drainage of cerebrospinal fluid (CSF), providing a means of lowering the ICP. Several catheter tip transducer systems are currently in clinical use, including using strain gauges or fiber-optical pressure sensing techniques. In these devices, zero drift and calibration cannot be checked in vivo. All the ICP monitoring devices in current clinical use require a physical connection between the brain and the external environment. This is a source of infection and limits the duration of monitoring. A number of telemetric monitoring devices, in which data is in some way transmitted transcutaneously, have been developed over the last twenty years, but significant technical problems have precluded their use in routine clinical practice. All current ICP monitors are temporary percutaneous implanted devices. Placement of these devices carries significant morbidity, particularly infection. Patients undergoing repeated monitoring require multiple surgical procedures. Apart from decreasing the risk of infection in patients with severe head injury, the clinical value of an accurate telemetric ICP monitoring system which maintains its reliability over a long period of implantation is high.

  14. Drift velocity and pressure monitoring of the CMS muon drift chambers

    CERN Document Server

    Sonnenschein, Lars

    2010-01-01

    The drift velocity in drift tubes of the CMS muon chambers is a key parameter for the muon track reconstruction and trigger. It needs to be monitored precisely in order to detect any deviation from its nominal value. A change in absolute pressure, a variation of the gas admixture or a contamination of the chamber gas by air affect the drift velocity. Furthermore, the temperature and magnetic field influence its value. First data, taken with a dedicated Velocity Drift Chamber (VDC) built by RWTH Aachen IIIA are presented. Another important parameter to be monitored is the pressure inside the muon drift tube chambers because the drift velocity depends on it. Furthermore the differential pressure must not exceed a certain value and the absolute pressure has to be kept slightly above ambient pressure to prevent air from entering into the muon drift tube chambers in case of a leak. Latest pressure monitoring results are discussed.

  15. Flow and pressure characteristics within a screw compressor

    Science.gov (United States)

    Guerrato, D.; Nouri, J. M.; Stosic, N.; Arcoumanis, C.

    2007-10-01

    The angle-resolved mean and turbulence characteristics of the axial air flow inside a screw compressor with both male and female rotors have been measured, using a laser Doppler velocimeter (LDV) with high spatial and temporal resolution at different radial and axial locations for speeds of 800-1600 rpm, discharge pressures of 1-1.6 bar and discharge temperatures of 33-90°C. The velocity measurements were performed through a special transparent window fixed near the discharge port. The results confirmed the ability of the LDV technique to characterise the flow inside the compressor working chamber; an angular resolution of 1.5° was able to fully describe the velocity field within the machine. The flow variation between the different working chambers was established as well as the spatial variation of the axial mean velocity and turbulence velocity fluctuation within the working chamber. The effect of discharge port opening on the axial mean and RMS velocities was found to be significant near the leading edge of the rotors causing an increase in the mean and RMS velocities of the order of 4.2Vp in mean (where Vp is the axial pitched velocity) for male rotor and 5.4Vp for, female rotor and this effect is less pronounced on the flow near the root of the rotor. Moreover, to obtain a better understanding of the flow motion, a high sampling rate pressure transducer was used to provide the internal angular static pressure variation. These measurements are used to validate the in-house CFD model of the fluid flow within twin screw compressors which, in turn, allows reliable optimisation of various compressor designs.

  16. Flow and pressure characteristics within a screw compressor

    International Nuclear Information System (INIS)

    Guerrato, D; Nouri, J M; Stosic, N; Arcoumanis, C

    2007-01-01

    The angle-resolved mean and turbulence characteristics of the axial air flow inside a screw compressor with both male and female rotors have been measured, using a laser Doppler velocimeter (LDV) with high spatial and temporal resolution at different radial and axial locations for speeds of 800-1600 rpm, discharge pressures of 1-1.6 bar and discharge temperatures of 33-90 0 C. The velocity measurements were performed through a special transparent window fixed near the discharge port. The results confirmed the ability of the LDV technique to characterise the flow inside the compressor working chamber; an angular resolution of 1.5 0 was able to fully describe the velocity field within the machine. The flow variation between the different working chambers was established as well as the spatial variation of the axial mean velocity and turbulence velocity fluctuation within the working chamber. The effect of discharge port opening on the axial mean and RMS velocities was found to be significant near the leading edge of the rotors causing an increase in the mean and RMS velocities of the order of 4.2V p in mean (where V p is the axial pitched velocity) for male rotor and 5.4V p for, female rotor and this effect is less pronounced on the flow near the root of the rotor. Moreover, to obtain a better understanding of the flow motion, a high sampling rate pressure transducer was used to provide the internal angular static pressure variation. These measurements are used to validate the in-house CFD model of the fluid flow within twin screw compressors which, in turn, allows reliable optimisation of various compressor designs

  17. Pressure calculations in nanochannel gas flows

    NARCIS (Netherlands)

    Kim, J.H.; Frijns, A.J.H.; Nedea, S.V.; Steenhoven, van A.A.; Frijns, A.J.H.; Valougeorgis, D.; Colin, S.; Baldas, L.

    2012-01-01

    In this research, pressure driven flow within a nanochannel is studied for argon in rarefied gas states. A Molecular Dynamics simulation is used to resolve the density and stress variations. Normal stress calculations are based on Irving-Kirkwood method, which divides the stress tensor into its

  18. Acute tamponade alters subendo- and subepicardial pressure-flow relations differently during vasodilation.

    Science.gov (United States)

    Kingma, J G; Martin, J; Rouleau, J R

    1994-07-01

    Instantaneous diastolic left coronary artery pressure-flow relations (PFR) shift during acute tamponade as pressure surrounding the heart increases. Coronary pressure at zero flow (Pf = 0) on the linear portion of the PFR is the weighted mean of the different myocardial waterfall pressures, the distribution of which varies across the left ventricular wall during diastole. However, instantaneous PFR measured in large epicardial coronary arteries cannot be used to estimate Pf = 0 in the different myocardial tissue layers. During coronary vasodilatation in a capacitance-free model, myocardial PFR differs from subendocardium to subepicardium. Therefore, we studied the effects of acute tamponade during maximal pharmacology induced coronary vasodilatation on myocardial PFR in in situ anesthetized dogs. Tamponade reduced cardiac output, aortic pressure, and coronary blood flow. Results demonstrate that different mechanisms influence distribution of myocardial blood flow during tamponade. Subepicardial vascular resistance is unchanged and the extrapolated Pf = 0 is increased, thereby shifting PFR to a higher intercept on the pressure axis. Subendocardial vascular resistance is increased while the extrapolated Pf = 0 remains unchanged. Results indicate that in the setting of acute tamponade with coronary vasodilatation different mechanisms regulate the distribution of myocardial blood flow: in the subepicardium only outflow pressure increases, whereas in the subendocardium only vascular resistance increases.

  19. Serial Network Flow Monitor

    Science.gov (United States)

    Robinson, Julie A.; Tate-Brown, Judy M.

    2009-01-01

    Using a commercial software CD and minimal up-mass, SNFM monitors the Payload local area network (LAN) to analyze and troubleshoot LAN data traffic. Validating LAN traffic models may allow for faster and more reliable computer networks to sustain systems and science on future space missions. Research Summary: This experiment studies the function of the computer network onboard the ISS. On-orbit packet statistics are captured and used to validate ground based medium rate data link models and enhance the way that the local area network (LAN) is monitored. This information will allow monitoring and improvement in the data transfer capabilities of on-orbit computer networks. The Serial Network Flow Monitor (SNFM) experiment attempts to characterize the network equivalent of traffic jams on board ISS. The SNFM team is able to specifically target historical problem areas including the SAMS (Space Acceleration Measurement System) communication issues, data transmissions from the ISS to the ground teams, and multiple users on the network at the same time. By looking at how various users interact with each other on the network, conflicts can be identified and work can begin on solutions. SNFM is comprised of a commercial off the shelf software package that monitors packet traffic through the payload Ethernet LANs (local area networks) on board ISS.

  20. Hazard Monitoring of Growing Lava Flow Fields Using Seismic Tremor

    Science.gov (United States)

    Eibl, E. P. S.; Bean, C. J.; Jónsdottir, I.; Hoskuldsson, A.; Thordarson, T.; Coppola, D.; Witt, T.; Walter, T. R.

    2017-12-01

    An effusive eruption in 2014/15 created a 85 km2 large lava flow field in a remote location in the Icelandic highlands. The lava flows did not threaten any settlements or paved roads but they were nevertheless interdisciplinarily monitored in detail. Images from satellites and aircraft, ground based video monitoring, GPS and seismic recordings allowed the monitoring and reconstruction of a detailed time series of the growing lava flow field. While the use of satellite images and probabilistic modelling of lava flows are quite common tools to monitor the current and forecast the future growth direction, here we show that seismic recordings can be of use too. We installed a cluster of seismometers at 15 km from the vents and recorded the ground vibrations associated with the eruption. This seismic tremor was not only generated below the vents, but also at the edges of the growing lava flow field and indicated the parts of the lava flow field that were most actively growing. Whilst the time resolution is in the range of days for satellites, seismic stations easily sample continuously at 100 Hz and could therefore provide a much better resolution and estimate of the lava flow hazard in real-time.

  1. Micro Coriolis mass flow sensor with integrated resistive pressure sensors

    NARCIS (Netherlands)

    Groenesteijn, Jarno; Alveringh, Dennis; Schut, Thomas; Wiegerink, Remco J.; Sparreboom, Wouter; Lötters, Joost Conrad

    2017-01-01

    We report on novel resistive pressure sensors, integrated on-chip at the inlet- and outlet-channels of a micro Coriolis mass flow sensor. The pressure sensors can be used to measure the pressure drop over the Coriolis sensor which can be used to compensate pressure-dependent behaviour that might

  2. Drift velocity and pressure monitoring of the CMS muon drift chambers

    CERN Document Server

    Sonnenschein, Lars

    2011-01-01

    The drift velocity in drift tubes of the CMS muon chambers is a key parameter for the muon track reconstruction and trigger. It needs to be monitored precisely in order to detect any deviation from its nominal value. A change in absolute pressure, a variation of the gas admixture or a contamination of the chamber gas by air affect the drift velocity. Furthermore, the temperature and magnetic field influence its value. First data, taken with a dedicated Velocity Drift Chamber (VDC) built by RWTH Aachen IIIA are presented. Another important parameter to be monitored is the pressure inside the muon drift tube chambers. The differential pressure must not exceed a certain value and the absolute pressure has to be kept slightly above ambient pressure to prevent air from entering into the muon drift tube chambers in case of a leak. Latest drift velocity monitoring results are discussed.

  3. Pressure-driven flow of a Herschel-Bulkley fluid with pressure-dependent rheological parameters

    Science.gov (United States)

    Panaseti, Pandelitsa; Damianou, Yiolanda; Georgiou, Georgios C.; Housiadas, Kostas D.

    2018-03-01

    The lubrication flow of a Herschel-Bulkley fluid in a symmetric long channel of varying width, 2h(x), is modeled extending the approach proposed by Fusi et al. ["Pressure-driven lubrication flow of a Bingham fluid in a channel: A novel approach," J. Non-Newtonian Fluid Mech. 221, 66-75 (2015)] for a Bingham plastic. Moreover, both the consistency index and the yield stress are assumed to be pressure-dependent. Under the lubrication approximation, the pressure at zero order depends only on x and the semi-width of the unyielded core is found to be given by σ(x) = -(1 + 1/n)h(x) + C, where n is the power-law exponent and the constant C depends on the Bingham number and the consistency-index and yield-stress growth numbers. Hence, in a channel of constant width, the width of the unyielded core is also constant, despite the pressure dependence of the yield stress, and the pressure distribution is not affected by the yield-stress function. With the present model, the pressure is calculated numerically solving an integro-differential equation and then the position of the yield surface and the two velocity components are computed using analytical expressions. Some analytical solutions are also derived for channels of constant and linearly varying widths. The lubrication solutions for other geometries are calculated numerically. The implications of the pressure-dependence of the material parameters and the limitations of the method are discussed.

  4. Reproduction of pressure field in ultrasonic-measurement-integrated simulation of blood flow.

    Science.gov (United States)

    Funamoto, Kenichi; Hayase, Toshiyuki

    2013-07-01

    Ultrasonic-measurement-integrated (UMI) simulation of blood flow is used to analyze the velocity and pressure fields by applying feedback signals of artificial body forces based on differences of Doppler velocities between ultrasonic measurement and numerical simulation. Previous studies have revealed that UMI simulation accurately reproduces the velocity field of a target blood flow, but that the reproducibility of the pressure field is not necessarily satisfactory. In the present study, the reproduction of the pressure field by UMI simulation was investigated. The effect of feedback on the pressure field was first examined by theoretical analysis, and a pressure compensation method was devised. When the divergence of the feedback force vector was not zero, it influenced the pressure field in the UMI simulation while improving the computational accuracy of the velocity field. Hence, the correct pressure was estimated by adding pressure compensation to remove the deteriorating effect of the feedback. A numerical experiment was conducted dealing with the reproduction of a synthetic three-dimensional steady flow in a thoracic aneurysm to validate results of the theoretical analysis and the proposed pressure compensation method. The ability of the UMI simulation to reproduce the pressure field deteriorated with a large feedback gain. However, by properly compensating the effects of the feedback signals on the pressure, the error in the pressure field was reduced, exhibiting improvement of the computational accuracy. It is thus concluded that the UMI simulation with pressure compensation allows for the reproduction of both velocity and pressure fields of blood flow. Copyright © 2012 John Wiley & Sons, Ltd.

  5. Effects of external pressure loading on human skin blood flow measured by 133Xe clearance

    International Nuclear Information System (INIS)

    Holloway, G.A. Jr.; Daly, C.H.; Kennedy, D.; Chimoskey, J.

    1976-01-01

    Forearm skin blood flow was measured during external pressure loading in normal human subjects using 133 Xe washout from intracutaneous injection sites. Pressures ranging between 5 and 150 mmHg were applied through a 3-cm-diameter disc placed over the site of flow determination. The pressure was maintained constant by a servo-controlled loading mechanism. Flow decreased with pressures from 5 to 10 and 30 to 150 mmHg, but remained constant with pressures from 10 to 30 mmHg. Reactive hyperemia occurred following removal of pressures of 90 mmHg or greater, but did not occur following removal of lower pressures. The pressure-flow curve for parasacral skin of paraplegic subjects closely paralleled the pressure-flow curve of normal skin at pressures tested: 5 to 15 mmHg. These data are interpreted to demonstrate autoregulation of skin blood flow. Autoregulation in parasacral skin of paraplegic subjects suggests a peripheral mechanism. The occurrence of hyperemia at pressures which exceed the ability of skin to autoregulate suggests that both autoregulation and post occlusion hyperemia may have the same mechanism

  6. Data Of Daily Blood Pressure Monitoring In Patients With Rheumatoid Arthritis

    Directory of Open Access Journals (Sweden)

    A.P. Rebrov

    2009-06-01

    Full Text Available The aim of present work is to study the frequency of hypertension and the peculiarity of 24-hour blood pressure monitoring in patients with rheumatoid arthritis. We studied 584 patients with rheumatoid arthritis. Daily blood pressure monitoring was carried out in 46 patients with arthritis and 18 patients with essential hypertension. Frequency of hypertension was higher in patients with arthritis then in general population. Elevation of systolic blood pressure, heart rate and arterial blood pressure adequate decrease at night were developed to associate with advance of the disease.

  7. Calculating e-flow using UAV and ground monitoring

    Science.gov (United States)

    Zhao, C. S.; Zhang, C. B.; Yang, S. T.; Liu, C. M.; Xiang, H.; Sun, Y.; Yang, Z. Y.; Zhang, Y.; Yu, X. Y.; Shao, N. F.; Yu, Q.

    2017-09-01

    Intense human activity has led to serious degradation of basin water ecosystems and severe reduction in the river flow available for aquatic biota. As an important water ecosystem index, environmental flows (e-flows) are crucial for maintaining sustainability. However, most e-flow measurement methods involve long cycles, low efficiency, and transdisciplinary expertise. This makes it impossible to rapidly assess river e-flows at basin or larger scales. This study presents a new method to rapidly assessing e-flows coupling UAV and ground monitorings. UAV was firstly used to calculate river-course cross-sections with high-resolution stereoscopic images. A dominance index was then used to identify key fish species. Afterwards a habitat suitability index, along with biodiversity and integrity indices, was used to determine an appropriate flow velocity with full consideration of the fish spawning period. The cross-sections and flow velocity values were then combined into AEHRA, an e-flow assessment method for studying e-flows and supplying-rate. To verify the results from this new method, the widely used Tennant method was employed. The root-mean-square errors of river cross-sections determined by UAV are less than 0.25 m, which constitutes 3-5% water-depth of the river cross-sections. In the study area of Jinan city, the ecological flow velocity (VE) is equal to or greater than 0.11 m/s, and the ecological water depth (HE) is greater than 0.8 m. The river ecosystem is healthy with the minimum e-flow requirements being always met when it is close to large rivers, which is beneficial for the sustainable development of the water ecosystem. In the south river channel of Jinan, the upstream flow mostly meets the minimum e-flow requirements, and the downstream flow always meets the minimum e-flow requirements. The north of Jinan consists predominantly of artificial river channels used for irrigation. Rainfall rarely meets the minimum e-flow and irrigation water requirements

  8. A Passive Flow-rate Regulator Using Pressure-dependent Autonomous Deflection of Parallel Membrane Valves

    International Nuclear Information System (INIS)

    Il, Doh; Cho, Young-Ho

    2009-01-01

    We present a passive flow-rate regulator, capable to compensate inlet pressure variation and to maintain a constant flow-rate for precise liquid control. Deflection of the parallel membrane valves in the passive flowrate regulator adjusts fluidic resistance according to inlet fluid pressure without any external energy. Compared to previous passive flow-rate regulators, the present device achieves precision flow regulation functions at the lower threshold compensation pressure of 20kPa with the simpler structure. In the experimental study, the fabricated device achieves the constant flow-rate of 6.09±0.32 μl/s over the inlet pressure range of 20∼50 kPa. The present flow-rate regulator having simple structure and lower compensation pressure level demonstrates potentials for use in integrated micropump systems

  9. An experimental study on two-phase flow pattern in low pressure natural circulation system

    International Nuclear Information System (INIS)

    Wu Shaorong; Han Bing; Zhou Lei; Zhang Youjie; Jiang Shengyao; Wu Xinxin

    1991-10-01

    An experimental study on two-phase flow pattern in the riser of low pressure natural circulation system was performed. The local differential pressure signal was analysed for flow pattern. It is considered that Sr f·d/v can be used to distinguish different flow patterns and it has clear and definite physical meaning. Flow patterns at different inlet temperature with different system pressures (1.5 MPa, 0.24 MPa and 0.1 MPa) are described. It is considered that the flow pattern is only bubble flow without flow pattern change during the period of low quality density-wave instability at 1.5 MPa. There is no density-wave oscillation in the system, when flow pattern is in bubble-intermittent transition area. The effect of flash vaporization on stability at low pressure is discussed

  10. Flow and pressure characteristics within a screw compressor

    Energy Technology Data Exchange (ETDEWEB)

    Guerrato, D; Nouri, J M; Stosic, N; Arcoumanis, C [Centre for Energy and the Environment, School of Engineering and Mathematical Sciences, City University, Northampton Square, London, EC1V OHB (United Kingdom)

    2007-10-15

    The angle-resolved mean and turbulence characteristics of the axial air flow inside a screw compressor with both male and female rotors have been measured, using a laser Doppler velocimeter (LDV) with high spatial and temporal resolution at different radial and axial locations for speeds of 800-1600 rpm, discharge pressures of 1-1.6 bar and discharge temperatures of 33-90{sup 0}C. The velocity measurements were performed through a special transparent window fixed near the discharge port. The results confirmed the ability of the LDV technique to characterise the flow inside the compressor working chamber; an angular resolution of 1.5{sup 0} was able to fully describe the velocity field within the machine. The flow variation between the different working chambers was established as well as the spatial variation of the axial mean velocity and turbulence velocity fluctuation within the working chamber. The effect of discharge port opening on the axial mean and RMS velocities was found to be significant near the leading edge of the rotors causing an increase in the mean and RMS velocities of the order of 4.2V{sub p} in mean (where V{sub p} is the axial pitched velocity) for male rotor and 5.4V{sub p} for, female rotor and this effect is less pronounced on the flow near the root of the rotor. Moreover, to obtain a better understanding of the flow motion, a high sampling rate pressure transducer was used to provide the internal angular static pressure variation. These measurements are used to validate the in-house CFD model of the fluid flow within twin screw compressors which, in turn, allows reliable optimisation of various compressor designs.

  11. Validation of the Kingyield BP210 wrist blood pressure monitor for home blood pressure monitoring according to the European Society of Hypertension-International Protocol.

    Science.gov (United States)

    Zeng, Wei-Fang; Huang, Qi-Fang; Sheng, Chang-Sheng; Li, Yan; Wang, Ji-Guang

    2012-02-01

    The present study aimed to evaluate the accuracy of the automated oscillometric wrist blood pressure monitor BP210 for home blood pressure monitoring according to the International Protocol of the European Society of Hypertension. Systolic and diastolic blood pressures were sequentially measured in 33 adult Chinese participants (21 women, 51 years of mean age) using a mercury sphygmomanometer (two observers) and the BP210 device (one supervisor). Ninety-nine pairs of comparisons were obtained from 15 participants in phase 1 and a further 18 participants in phase 2 of the validation study. Data analysis was conducted using the ESHIP analyzer. The BP210 device successfully passed phase 1 of the validation study with a number of absolute differences between device and observers within 5, 10, and 15 mmHg for at least 33/45, 44/45, and 44/45 measurements, respectively. The device also achieved the targets for phase 2.1, with 77/99, 95/99, and 97/99 differences within 5, 10, and 15 mmHg, respectively for systolic blood pressure, and with 78/99, 97/99, and 99/99 within 5, 10, and 15 mmHg, respectively for diastolic blood pressure. In phase 2.2, 29 and 25 participants had at least two of the three device-observers differences within 5 mmHg (required≥22) for systolic blood pressure and diastolic blood pressure, respectively. The Kingyield wrist blood pressure monitor BP210 has passed the International Protocol requirements, and hence can be recommended for home use in adults.

  12. Instantaneous planar pressure determination from PIV in turbulent flow

    NARCIS (Netherlands)

    De Kat, R.; Van Oudheusden, B.W.

    2011-01-01

    This paper deals with the determination of instantaneous planar pressure fields from velocity data obtained by particle image velocimetry (PIV) in turbulent flow. The operating principles of pressure determination using a Eulerian or a Lagrangian approach are described together with theoretical

  13. Boiling on a tube bundle: heat transfer, pressure drop and flow patterns

    International Nuclear Information System (INIS)

    Agostini, F.

    2008-07-01

    The complexity of the two-phase flow in a tube bundle presents important problems in the design and understanding of the physical phenomena taking place. The working conditions of an evaporator depend largely on the dynamics of the two-phase flow that in turn influence the heat exchange and the pressure drop of the system. A characterization of the flow dynamics, and possibly the identification of the flow pattern in the tube bundle, is thus expected to lead to a better understanding of the phenomena and to reveal on the mechanisms governing the tube bundle. Therefore, the present study aims at providing further insights into two-phase bundle flow through a new visualization system able to provide for the first time a view of the flow in the core of a tube bundle. In addition, the measurement of the light attenuation of a laser beam through the two-phase flow and measurement of the high frequency pressure fluctuations with a piezo-electric pressure transducer are used to characterize the flow. The design and the validation of this new instrumentation also provided a method for the detection of dry-out in tube bundles. This was achieved by a laser attenuation technique, flow visualization, and estimation of the power spectrum of the pressure fluctuation. The current investigation includes results for two different refrigerants, R134a and R236fa, three saturations temperatures T sat = 5, 10 and 15 °C, mass velocities ranging from 4 to 40 kg/sm² in adiabatic and diabatic conditions (several heat fluxes). Measurement of the local heat transfer coefficient and two-phase frictional pressure drop were obtained and utilized to improve the current prediction methods. The heat transfer and pressure drop data were supported by extensive characterization of the two-phase flow, which was to improve the understanding of the two-phase flow occurring in tube bundles. (author)

  14. Smart monitoring of fluid intake and bladder voiding using pressure sensitive mats.

    Science.gov (United States)

    Cohen-McFarlane, Madison; Green, James R; Knoefel, Frank; Goubran, Rafik

    2016-08-01

    Pressure sensitive mats have been used in noninvasive smart monitoring for a variety of problems including breathing rate monitoring, sleep monitoring, mobility, and weight. This paper describes a proof of concept application of pressure mats to monitor fluid intake/output (fluid cycle) events during the night. The ability to more accurately track such events has potential implications for monitoring those individuals who have nocturia, a condition where a person wakes at night to urinate. Data were collected from a healthy young female subject instructed to drink as much water as was comfortable (700mL) and lie in a supine position on a mattress located directly on three pressure mats. This was compared to an initial data set collected immediately after voiding but before drinking, 30 minutes after drinking, 60 minutes after drinking and a final data set after again voiding the bladder. The additional pressure from the 700mL of water was detectible and tracked over the course of the hour-long testing session under idealized conditions. This provides a proof-of-concept that nocturnal fluid intake and bladder voiding events can be tracked using non-invasive pressure-sensitive mats, however additional testing and development is required to achieve a deployable monitoring system.

  15. Wireless-accessible sensor populations for monitoring biological variables

    NARCIS (Netherlands)

    Mazzu, Marco; Scalvini, Simonetta; Giordano, A.; Frumento, E.; Wells, Hannah; Lokhorst, C.; Glisenti, Fulvio

    2008-01-01

    The current health-care infrastructure is generally considered to be inadequate to meet the needs of an increasingly older population. We have investigated the feasibility of a passive in-home monitoring system based on wireless accessible sensor populations (WASP). In an EU-funded project we have

  16. Basal interstitial water pressure in laboratory debris flows over a rigid bed in an open channel

    Directory of Open Access Journals (Sweden)

    N. Hotta

    2012-08-01

    Full Text Available Measuring the interstitial water pressure of debris flows under various conditions gives essential information on the flow stress structure. This study measured the basal interstitial water pressure during debris flow routing experiments in a laboratory flume. Because a sensitive pressure gauge is required to measure the interstitial water pressure in shallow laboratory debris flows, a differential gas pressure gauge with an attached diaphragm was used. Although this system required calibration before and after each experiment, it showed a linear behavior and a sufficiently high temporal resolution for measuring the interstitial water pressure of debris flows. The values of the interstitial water pressure were low. However, an excess of pressure beyond the hydrostatic pressure was observed with increasing sediment particle size. The measured excess pressure corresponded to the theoretical excess interstitial water pressure, derived as a Reynolds stress in the interstitial water of boulder debris flows. Turbulence was thought to induce a strong shear in the interstitial space of sediment particles. The interstitial water pressure in boulder debris flows should be affected by the fine sediment concentration and the phase transition from laminar to turbulent debris flow; this should be the subject of future studies.

  17. A combination of HPLC and automated data analysis for monitoring the efficiency of high-pressure homogenization.

    Science.gov (United States)

    Eggenreich, Britta; Rajamanickam, Vignesh; Wurm, David Johannes; Fricke, Jens; Herwig, Christoph; Spadiut, Oliver

    2017-08-01

    Cell disruption is a key unit operation to make valuable, intracellular target products accessible for further downstream unit operations. Independent of the applied cell disruption method, each cell disruption process must be evaluated with respect to disruption efficiency and potential product loss. Current state-of-the-art methods, like measuring the total amount of released protein and plating-out assays, are usually time-delayed and involve manual intervention making them error-prone. An automated method to monitor cell disruption efficiency at-line is not available to date. In the current study we implemented a methodology, which we had originally developed to monitor E. coli cell integrity during bioreactor cultivations, to automatically monitor and evaluate cell disruption of a recombinant E. coli strain by high-pressure homogenization. We compared our tool with a library of state-of-the-art methods, analyzed the effect of freezing the biomass before high-pressure homogenization and finally investigated this unit operation in more detail by a multivariate approach. A combination of HPLC and automated data analysis describes a valuable, novel tool to monitor and evaluate cell disruption processes. Our methodology, which can be used both in upstream (USP) and downstream processing (DSP), describes a valuable tool to evaluate cell disruption processes as it can be implemented at-line, gives results within minutes after sampling and does not need manual intervention.

  18. Large scale steam flow test: Pressure drop data and calculated pressure loss coefficients

    International Nuclear Information System (INIS)

    Meadows, J.B.; Spears, J.R.; Feder, A.R.; Moore, B.P.; Young, C.E.

    1993-12-01

    This report presents the result of large scale steam flow testing, 3 million to 7 million lbs/hr., conducted at approximate steam qualities of 25, 45, 70 and 100 percent (dry, saturated). It is concluded from the test data that reasonable estimates of piping component pressure loss coefficients for single phase flow in complex piping geometries can be calculated using available engineering literature. This includes the effects of nearby upstream and downstream components, compressibility, and internal obstructions, such as splitters, and ladder rungs on individual piping components. Despite expected uncertainties in the data resulting from the complexity of the piping geometry and two-phase flow, the test data support the conclusion that the predicted dry steam K-factors are accurate and provide useful insight into the effect of entrained liquid on the flow resistance. The K-factors calculated from the wet steam test data were compared to two-phase K-factors based on the Martinelli-Nelson pressure drop correlations. This comparison supports the concept of a two-phase multiplier for estimating the resistance of piping with liquid entrained into the flow. The test data in general appears to be reasonably consistent with the shape of a curve based on the Martinelli-Nelson correlation over the tested range of steam quality

  19. A microcatalytic flow reactor for the study of heterogeneous catalytic reactions at elevated pressures

    Energy Technology Data Exchange (ETDEWEB)

    Belyi, A S; Fomichev, Yu V; Duplyakin, V K; Alfeev, V S

    1977-07-01

    A microcatalytic flow reactor for the study of heterogeneous catalytic reactions at elevated pressures (i.e., up to 40 atm) and nearly isothermal conditions up to 600/sup 0/C was designed for the conversion of small quantities of petrochemical feeds or feed mixtures at uniform, controllable flow rates of 0.5-5.0 cc/hr, for direct gas-chromatographic analysis of product samples at the reactor outlet, and for continuous monitoring of the degree of conversion in processes that evolve or absorb hydrogen. The device includes a feed injection system with a unique sealing feature that ensures a constant flow of liquid from a feed buret under positive displacement by a counterweight piston at very low rates into a tubular reactor of the perfect mixing type, a highly efficient vaporizer-mixer, and a two-channel sampler leading to the chromatograph. The apparatus has proved reliable, accurate, and convenient in two years of regular use. Diagrams.

  20. Extended Sleeve Products Allow Control and Monitoring of Process Fluid Flows Inside Shielding, Behind Walls and Beneath Floors - 13041

    Energy Technology Data Exchange (ETDEWEB)

    Abbott, Mark W. [Flowserve Corporation, 1978 Foreman Drive Cookeville, TN 38506 (United States)

    2013-07-01

    Throughout power generation, delivery and waste remediation, the ability to control process streams in difficult or impossible locations becomes increasingly necessary as the complexity of processes increases. Example applications include radioactive environments, inside concrete installations, buried in dirt, or inside a shielded or insulated pipe. In these situations, it is necessary to implement innovative solutions to tackle such issues as valve maintenance, valve control from remote locations, equipment cleaning in hazardous environments, and flow stream analysis. The Extended Sleeve family of products provides a scalable solution to tackle some of the most challenging applications in hazardous environments which require flow stream control and monitoring. The Extended Sleeve family of products is defined in three groups: Extended Sleeve (ESV), Extended Bonnet (EBV) and Instrument Enclosure (IE). Each of the products provides a variation on the same requirements: to provide access to the internals of a valve, or to monitor the fluid passing through the pipeline through shielding around the process pipe. The shielding can be as simple as a grout filled pipe covering a process pipe or as complex as a concrete deck protecting a room in which the valves and pipes pass through at varying elevations. Extended Sleeves are available between roughly 30 inches and 18 feet of distance between the pipeline centerline and the top of the surface to which it mounts. The Extended Sleeve provides features such as ± 1.5 inches of adjustment between the pipeline and deck location, internal flush capabilities, automatic alignment of the internal components during assembly and integrated actuator mounting pads. The Extended Bonnet is a shorter fixed height version of the Extended Sleeve which has a removable deck flange to facilitate installation through walls, and is delivered fully assembled. The Instrument Enclosure utilizes many of the same components as an Extended Sleeve

  1. 40 CFR 63.1258 - Monitoring Requirements.

    Science.gov (United States)

    2010-07-01

    ... volumetric flow rate of supplemental gases, Vs, and the volumetric flow rate of all gases, Va, each time a... gauge or other pressure measurement device that can be read from a readily accessible location to verify...

  2. DETERMINANTS OF SUBOPTIMAL BLOOD PRESSURE CONTROL IN HYPERTENSIVE PATIENTS: 24-HOUR AMBULATORY BLOOD PRES-SURE MONITORING

    Directory of Open Access Journals (Sweden)

    Mansoor Moazenzadeh

    2010-12-01

    Full Text Available Abstract    INTRODUCTION: The study was conducted to define the determinants of suboptimal blood pressure (BP control among hypertensive patients under treatment and explore a predictive model for detecting the patients at risk for increased BP.    METHODS: We enrolled 97 patients (40 males, 57 females under treatment for hypertension between June 2006 and May 2007 in Shafa hospital, Kerman, Iran. BP was measured at clinic twice within 5-minute intervals. After setting up ambulatory blood pressure monitoring (ABPM, BP was measured at 30-minute intervals during the day and 60-minute intervals during the night. The frequency of increased BP (more than 140/90 mmHg was included in a regression model as dependent variable and all the others such as age, sex, body mass index (BMI, drugs and baseline clinical measurements as the predictors.    RESULTS: Increased BP was detected in 44% (95% CI: 38.79%-49.65% of all measurements during 24-hour monitoring. The frequency of increased BP had a significant relationship with BMI (b=0.35, P=0.001. Clinic's pulse pressure was a significant predicting factor for BP increase (P=0.02.    CONCLUSION: BMI and pulse pressure are the best predictors for being hypertensive during lifetime. Ineffective treatment of hypertension is frequent among the hypertensive patients.      Keywords: Blood pressure control, Pulse pressure, Ambulatory blood pressure monitoring (ABPM, BMI.

  3. A Mathematical Scheme for Calculating Flows and Pressure Drops in Lit and Unlit Cigarettes

    Directory of Open Access Journals (Sweden)

    Dwyer RW

    2014-12-01

    Full Text Available A computational methodology is presented for evaluating the flows and pressure drops in both lit and unlit cigarettes. The flows and pressure drops across rows of tipping-paper perforations are considered explicitly, as are the locations and relative sizes of the ventilation holes. The flows and pressure drops across air-permeable cigarette papers are included. The influence of plugwrappermeabilities on filter ventilation is developed. Lit cigarettes are mimicked by adding a “coal” pressure drop to the upstream end of the cigarette. The computational scheme is used to predict the effects of tobacco-rod length, puff volume, and vent blocking on cigarette ventilation and pressure drop. A derivation of the pressure-drop and flow equations for a cigarette with an upstream pressure drop is included in an appendix.

  4. Ambulatory and home blood pressure monitoring: gaps between clinical guidelines and clinical practice in Singapore.

    Science.gov (United States)

    Setia, Sajita; Subramaniam, Kannan; Teo, Boon Wee; Tay, Jam Chin

    2017-01-01

    Out-of-office blood pressure (BP) measurements (home blood pressure monitoring [HBPM] and ambulatory blood pressure monitoring [ABPM]) provide important additional information for effective hypertension detection and management decisions. Therefore, out-of-office BP measurement is now recommended by several international guidelines. This study evaluated the practice and uptake of HBPM and ABPM among physicians from Singapore. A sample of physicians from Singapore was surveyed between 8 September and 5 October 2016. Those included were in public or private practice had been practicing for ≥3 years, directly cared for patients ≥70% of the time, and treated ≥30 patients for hypertension per month. The questionnaire covered six main categories: general BP management, BP variability (BPV) awareness/diagnosis, HBPM, ABPM, BPV management, and associated training needs. Sixty physicians (30 general practitioners, 20 cardiologists, and 10 nephrologists) were included (77% male, 85% aged 31-60 years, and mean 22-year practice). Physicians recommended HBPM and ABPM to 81% and 27% of hypertensive patients, respectively. HBPM was most often used to monitor antihypertensive therapy (88% of physicians) and 97% thought that ABPM was useful for providing information on BPV. HBPM instructions often differed from current guideline recommendations in terms of frequency, number of measurements, and timing. The proportion of consultation time devoted to discussing HBPM and BPV was one-quarter or less for 73% of physicians, and only 55% said that they had the ability to provide education on HBPM and BPV. Patient inertia, poor patient compliance, lack of medical consultation time, and poor patient access to a BP machine were the most common challenges for implementing out-of-office BP monitoring. Although physicians from Singapore do recommend out-of-office BP measurement to patients with hypertension, this survey identified several important gaps in knowledge and clinical practice.

  5. Resistance calculation of un-fully developed two-phase flow through high differential pressure regulating valves

    International Nuclear Information System (INIS)

    Xu Mingyang; Wang Wenran; Wang Jiaying

    1999-01-01

    To reduce the flow velocity in the high differential pressure regulating valve with labyrinth. A type of complicated valve core structure were designed with tortuous flow path made from reversal double elbows. It is very difficult to calculate the pressure-drop of the un-fully developed two-phase flow under high temperature and pressure which flow through the valve core. A calculation method called 'constant (varing) pressure-drop progressing step by step design method' was developed. The complicated flow path was disintegrated into a series of independent resistance units and with the valve stem end progressing step by step the dimensions of the flow path were designed in accordance with the principle that in every position the total pressure-drop of the valve should amount to that required by the design goal curve. In the course of calculating the total pressure-drop, the valve flow path was also divided into a series of independent resistance units. The experiment results show that design flow characteristics are approximately consistent with the flow characteristics measured in the test

  6. Ambulatory blood pressure and adherence monitoring: diagnosing pseudoresistant hypertension.

    Science.gov (United States)

    Burnier, Michel; Wuerzner, Gregoire

    2014-01-01

    A small proportion of the treated hypertensive population consistently has a blood pressure greater than 140/90 mm Hg despite a triple therapy including a diuretic, a calcium channel blocker, and a blocker of the renin-angiotensin system. According to guidelines, these patients have so-called resistant hypertension. The prevalence of this clinical condition is higher in tertiary than primary care centers and often is associated with chronic kidney disease, diabetes, obesity, and sleep apnea syndrome. Exclusion of pseudoresistant hypertension using ambulatory or home blood pressure monitoring is a crucial step in the investigation of patients with resistant hypertension. Thus, among the multiple factors to consider when investigating patients with resistant hypertension, ambulatory blood pressure monitoring should be performed very early. Among other factors to consider, physicians should investigate patient adherence to therapy, assess the adequacy of treatment, exclude interfering factors, and, finally, look for secondary forms of hypertension. Poor adherence to therapy accounts for 30% to 50% of cases of resistance to therapy depending on the methodology used to diagnose adherence problems. This review discusses the clinical factors implicated in the pathogenesis of resistant hypertension with a particular emphasis on pseudoresistance, drug adherence, and the use of ambulatory blood pressure monitoring for the diagnosis and management of resistant hypertension.

  7. Type GQS-1 high pressure steam manifold water level monitoring system

    International Nuclear Information System (INIS)

    Li Nianzu; Li Beicheng; Jia Shengming

    1993-10-01

    The GQS-1 high pressure steam manifold water level monitoring system is an advanced nuclear gauge that is suitable for on-line detecting and monitor in high pressure steam manifold water level. The physical variable of water level is transformed into electrical pulses by the nuclear sensor. A computer is equipped for data acquisition, analysis and processing and the results are displayed on a 14 inch color monitor. In addition, a 4 ∼ 20 mA output current is used for the recording and regulation of water level. The main application of this gauge is for on-line measurement of high pressure steam manifold water level in fossil-fired power plant and other industries

  8. Integrated pressure sensing using capacitive Coriolis mass flow sensors

    NARCIS (Netherlands)

    Alveringh, Dennis; Wiegerink, Remco J.; Lötters, Joost Conrad

    2017-01-01

    The cross-sectional shape of microchannels is, dependent on the fabrication method, never perfectly circular. Consequently, the channels deform with the pressure, which is a non-ideal effect in flow sensors, but may be used for pressure sensing. Multiple suspended channels with different lengths

  9. Pressure and velocity dependence of flow-type cavitation erosion

    CSIR Research Space (South Africa)

    Auret, JG

    1993-12-01

    Full Text Available Previous results on the influence of water pressure and velocity on flow-type cavitations erosion, i.e. an increase in erosion rate with increasing velocity and peaking of erosion rate as a function of pressure, were confirmed by measurements with a...

  10. Use of home blood-pressure monitoring in the detection, treatment and surveillance of hypertension.

    Science.gov (United States)

    Manning, Gillian; Donnelly, Richard

    2005-11-01

    Use of home blood-pressure monitoring is increasing but the technique and the equipment have limitations. We provide an overview of recent evidence in this rapidly evolving field. Home blood-pressure monitoring is an acceptable method for screening patients for hypertension. There is increasing evidence supporting the predictive power of home blood pressure for stroke risk even in the general population. The identification of white-coat and masked hypertension remains an important role for home blood-pressure monitoring. Unvalidated equipment and poor patient technique are major concerns. The purchase of devices needs to be linked to a simple patient-education programme, which is perhaps an opportunity for collaboration between healthcare providers and commercial companies. Devices that store the blood-pressure measurements in the memory are preferred to ensure accuracy of reporting. Data-transmission systems providing automatic storage, transmission and reporting of blood pressure, direct involvement of the patient and potentially a reduced number of hospital/general practitioner visits, offer significant advantages. To reduce patient anxiety, overuse of home blood-pressure monitoring should be avoided but there is the potential for self-modification of treatment, subject to certain safeguards. Self-monitoring of blood pressure is developing rapidly, linked to increasing awareness of the impact of reducing high blood pressure on public health and the marketing/advertising strategies used to sell automatic devices. Home blood-pressure monitoring has a role in the detection and management of blood pressure, but not at the expense of careful blood-pressure measurement in the office and adherence to national guidelines.

  11. Glucose Monitoring System Based on Osmotic Pressure Measurements

    Directory of Open Access Journals (Sweden)

    Alexandra LEAL

    2011-02-01

    Full Text Available This paper presents the design and development of a prototype sensor unit for implementation in a long-term glucose monitoring system suitable for estimating glucose levels in people suffering from diabetes mellitus. The system utilizes osmotic pressure as the sensing mechanism and consists of a sensor prototype that is integrated together with a pre-amplifier and data acquisition unit for both data recording and processing. The sensor prototype is based on an embedded silicon absolute pressure transducer and a semipermeable nanoporous membrane that is enclosed in the sensor housing. The glucose monitoring system facilitates the integration of a low power microcontroller that is combined with a wireless inductive powered communication link. Experimental verification have proven that the system is capable of tracking osmotic pressure changes using albumin as a model compound, and thereby show a proof of concept for novel long term tracking of blood glucose from remote sensor nodes.

  12. Ambulatory and home blood pressure monitoring: gaps between clinical guidelines and clinical practice in Singapore

    Directory of Open Access Journals (Sweden)

    Setia S

    2017-07-01

    only 55% said that they had the ability to provide education on HBPM and BPV. Patient inertia, poor patient compliance, lack of medical consultation time, and poor patient access to a BP machine were the most common challenges for implementing out-of-office BP monitoring. Conclusion: Although physicians from Singapore do recommend out-of-office BP measurement to patients with hypertension, this survey identified several important gaps in knowledge and clinical practice. Keywords: hypertension, blood pressure monitoring, blood pressure variability, guidelines

  13. Monitoring User-Based Accessibility Assessment in Urban Environments and in Public Buildings

    Directory of Open Access Journals (Sweden)

    Gintaras Stauskis

    2018-04-01

    Full Text Available The research features analysis of user-experience-based accessibility assessment and progress monitoring of buildings and public spaces; this analysis is used as a tool for facilitating the development of humane, socially sustainable and an inclusive urban environment. A group of users representing people with different kinds of disabilities, the elderly and families with children was created to assess the quality of access to various buildings with different functions and locations across Vilnius and in Singapore. A school, two hospitals, a rehab centre and two offices were selected for access monitoring in Vilnius City, while a hotel, a café and two metro stations with public squares were chosen for access assessment in Singapore. As the same method was principally applied to assess accessibility of selected buildings in Vilnius City in 2000 and 2017 and in Singapore in 2012, the article draws a comparative analysis of access levels in these two cities located in different global regions. The results show a definite improvement of access quality over time and also identify the critical aspects in this process. The segment of plot planning represents the lowest quality of access for all assessed building types as compared to the building segment and the external–internal element segments. The paper also draws conclusions that access improvement is a continuous process of implementing advanced urban policy instruments, and city planners can contribute to it by constantly analysing and presenting to public the monitoring data about the progress in access improvement. Comparing the assessment results between Vilnius City and Singapore – cities that are located in different global regions and in different socio-economic environments – provides a practical tool for benchmarking and setting the priorities for this process.

  14. On-line fatigue monitoring system for reactor pressure vessel

    International Nuclear Information System (INIS)

    Tokunaga, K.; Sakai, A.; Aoki, T.; Ranganath, S.; Stevens, G.L.

    1994-01-01

    A workstation-based, on-line fatigue monitoring system for tracking fatigue usage applied to an operating boiling water reactor (BWR), Tsuruga Unit-1, is described. The system uses the influence function approach and determines component stresses using temperature, pressure, and flow rate data that are made available via signal taps from previously existing plant sensors. Using plant unique influence functions developed specifically for the feedwater nozzle location, the system calculates stresses as a function of time and computed fatigue usage. The analysis method used to compute fatigue usage complies with MITI Code Notification No.501. Fatigue usage results for an entire fuel cycle are presented and compared to assumed design basis events to confirm that actual plant thermal duty is significantly less severe than originally estimated in the design basis stress report. As a result, the system provides the technical basis to more accurately evaluate actual reactor conditions as well as the justification for plant life extension. (author)

  15. Flow instability research on steam generator with straight double-walled heat transfer tube for FBR. Pressure drop under high pressure condition

    International Nuclear Information System (INIS)

    Liu, Wei; Tamai, Hidesada; Yoshida, Hiroyuki; Takase, Kazuyuki; Hayafune, Hiroki; Futagami, Satoshi; Kisohara, Naoyuki

    2008-01-01

    For the Steam Generator (SG) with straight double-walled heat transfer tube that used in sodium cooled Faster Breeder Reactor, flow instability is one of the most important items need researching. As the first step of the research, thermal hydraulics experiments were performed under high pressure condition in JAEA with using a straight tube. Pressure drop, heat transfer coefficients and void fraction data were derived. This paper evaluates the pressure drop data with TRAC-BF1 code. The Pffan's correlation for single phase flow and the Martinelli-Nelson's two-phase flow multiplier are found can be well predicted the present pressure drop data under high pressure condition. (author)

  16. Validation of the Rossmax CF175 upper-arm blood pressure monitor for home blood pressure monitoring according to the European Society of Hypertension International Protocol revision 2010.

    Science.gov (United States)

    Zhang, Lu; Kang, Yuan-Yuan; Zeng, Wei-Fang; Li, Yan; Wang, Ji-Guang

    2015-04-01

    The present study aimed to evaluate the accuracy of the Rossmax CF175 upper-arm blood pressure monitor for home blood pressure monitoring according to the International Protocol of the European Society of Hypertension revision 2010. Systolic and diastolic blood pressures were sequentially measured in 33 adult Chinese (17 women, mean age 46 years) using a mercury sphygmomanometer (two observers) and the Rossmax CF175 device (one supervisor). A total of 99 pairs of comparisons were obtained from 33 participants for judgments in two parts with three grading phases. All the blood pressure requirements were fulfilled. The Rossmax CF175 device achieved the targets in part 1 of the validation study. The number of absolute differences between the device and observers within 5, 10, and 15 mmHg was 78/99, 94/99, and 98/99, respectively, for systolic blood pressure, and 81/99, 96/99, and 97/99, respectively, for diastolic blood pressure. The device also achieved the criteria in part 2 of the validation study. Twenty-nine participants, for both of systolic and diastolic blood pressure, had at least two of the three device-observers differences within 5 mmHg (required ≥24). Only one participant for diastolic blood pressure had all three device-observers comparisons greater than 5 mmHg. The Rossmax automated oscillometric upper-arm blood pressure monitor CF175 fulfilled the requirements of the International Protocol revision 2010, and hence can be recommended for blood pressure measurement in adults.

  17. Calculation of pressure drop and flow redistribution in the LMFBR core

    International Nuclear Information System (INIS)

    Morgado, O.J.

    1984-01-01

    The flow redistribution through fuel assemblies of LMFBRs: for the correct calculation of mass flow rates and pressure drop, are studied. Using a quasi-static formulation of conservation equations of mass and energy, a computer program was developed to simulate any arbitrary number of flow channels, operating at different linear power levels. Therefore f flow channels, operating at different linear power levels. Therefore, it was possible to perform thermal transient calculations for the Clinch River reactor core. The results of the calculations agree with the data found in the literature and supply accurate information about flow redistribution, average temperature, and pressure drop in the core, when the reactor is operated at conditions from the designed flow conditions, as is always the case in a load changing operation, or during transients. (Autor) [pt

  18. Methods for monitoring heat flow intensity in the blast furnace wall

    Directory of Open Access Journals (Sweden)

    L'. Dorčák

    2010-04-01

    Full Text Available In this paper we present the main features of an online system for real-time monitoring of the bottom part of the blast furnace. Firstly, monitoring concerns the furnace walls and furnace bottom temperatures measurement and their visualization. Secondly, monitored are the heat flows of the furnace walls and furnace bottom. In the case of two measured temperatures, the heat flow is calculated using multi-layer implicit difference scheme and in the case of only one measured temperature, the heat flow is calculated using a method based on application of fractional-order derivatives. Thirdly, monitored is the theoretical temperature of the blast furnace combustion process in the area of tuyeres.

  19. Continuous wireless pressure monitoring and mapping with ultra-small passive sensors for health monitoring and critical care.

    Science.gov (United States)

    Chen, Lisa Y; Tee, Benjamin C-K; Chortos, Alex L; Schwartz, Gregor; Tse, Victor; Lipomi, Darren J; Wong, H-S Philip; McConnell, Michael V; Bao, Zhenan

    2014-10-06

    Continuous monitoring of internal physiological parameters is essential for critical care patients, but currently can only be practically achieved via tethered solutions. Here we report a wireless, real-time pressure monitoring system with passive, flexible, millimetre-scale sensors, scaled down to unprecedented dimensions of 1 × 1 × 0.1 cubic millimeters. This level of dimensional scaling is enabled by novel sensor design and detection schemes, which overcome the operating frequency limits of traditional strategies and exhibit insensitivity to lossy tissue environments. We demonstrate the use of this system to capture human pulse waveforms wirelessly in real time as well as to monitor in vivo intracranial pressure continuously in proof-of-concept mice studies using sensors down to 2.5 × 2.5 × 0.1 cubic millimeters. We further introduce printable wireless sensor arrays and show their use in real-time spatial pressure mapping. Looking forward, this technology has broader applications in continuous wireless monitoring of multiple physiological parameters for biomedical research and patient care.

  20. Coronary oscillatory flow amplitude is more affected by perfusion pressure than ventricular pressure.

    Science.gov (United States)

    Krams, R; Sipkema, P; Westerhof, N

    1990-06-01

    In this study on the isolated, maximally vasodilated, blood-perfused cat heart we investigated the relation between left ventricular developed pressure (delta Piv) and coronary oscillatory flow amplitude (diastolic minus systolic flow, delta F) at different levels of constant perfusion pressure (Pp). We hypothesized that the effect of cardiac contraction on the phasic flow results from the changing elastic properties of cardiac muscle. The coronary vessel compartment can, as can the left ventricular lumen compartment, be described by a time-varying elastance. This concept predicts that the effect of left ventricular pressure on delta F is small, whereas the effect of Pp is considerable. Both the waterfall model and the intramyocardial pump model predict the inverse. The relation between delta Piv and delta F at a Pp of 10 kPa is delta F = (4.71 +/- 3.08).delta Piv + 337 +/- 75 (slope in ml.min-1.100 g-1.kPa-1 and intercept in ml.min-1.100 g-1; n = 7); the relation between (constant levels of) Pp and delta F at a constant delta Piv of 10 kPa is delta F = 51.Pp + 211 (slope in ml.min-1.100 g-1.kPa-1 and intercept in ml.min-1.100 g-1; n = 6). The differences in slope are best predicted by the time-varying elastance concept.

  1. Validation of the SCIAN LD-735 wrist blood pressure monitor for home blood pressure monitoring according to the European Society of Hypertension International Protocol revision 2010.

    Science.gov (United States)

    Kang, Yuan-Yuan; Chen, Qi; Li, Yan; Wang, Ji-Guang

    2016-08-01

    This study aimed to evaluate the accuracy of the automated oscillometric wrist blood pressure monitor SCIAN LD-735 for home blood pressure monitoring according to the International Protocol of the European Society of Hypertension revision 2010. Systolic and diastolic blood pressures were measured sequentially in 33 adult Chinese participants (10 women, mean age 44.8 years) using a mercury sphygmomanometer (two observers) and the SCIAN LD-735 device (one supervisor). A total of 99 pairs of comparisons were obtained from 33 participants for judgments in two parts with three grading phases. The SCIAN LD-735 device achieved the targets in part 1 of the validation study. The number of absolute differences between device and observers within 5, 10, and 15 mmHg was 86/99, 97/99, and 98/99, respectively, for systolic blood pressure and 85/99, 98/99, and 99/99, respectively, for diastolic blood pressure. The device also fulfilled the criteria in part 2 of the validation study. In total, 30 and 33 participants for systolic and diastolic blood pressure, respectively, had at least two of the three device-observer differences within 5 mmHg (required ≥24). No participant had all of the three device-observer comparisons greater than 5 mmHg for systolic or diastolic blood pressure. The SCIAN wrist blood pressure monitor LD-735 has passed the requirements of the International Protocol revision 2010, and hence can be recommended for home use in adults.

  2. Validation of the AVITA BPM17 wrist blood pressure monitor for home blood pressure monitoring according to the European Society of Hypertension International Protocol revision 2010.

    Science.gov (United States)

    Kang, Yuan-Yuan; Chen, Qi; Liu, Chang-Yuan; Li, Yan; Wang, Ji-Guang

    2017-08-01

    The aim of the present study was to evaluate the accuracy of the automated oscillometric wrist blood pressure monitor AVITA BPM17 for home blood pressure monitoring according to the International Protocol of the European Society of Hypertension revision 2010. Systolic and diastolic blood pressures were sequentially measured in 33 adult Chinese (19 men, 45.7 years of mean age) using a mercury sphygmomanometer (two observers) and the AVITA BPM17 device (one supervisor). Ninety-nine pairs of comparisons were obtained from 33 participants for judgments in two parts with three grading phases. The AVITA BPM17 device achieved the targets in part 1 of the validation study. The number of absolute differences between device and observers within 5, 10, and 15 mmHg was 94/99, 98/99, and 98/99, respectively, for systolic blood pressure and 92/99, 99/99, and 99/99, respectively, for diastolic blood pressure. The device also fulfilled the criteria in part 2 of the validation study. Overall, 32 participants for both systolic and diastolic blood pressure, respectively, had at least two of the three device-observerss differences within 5 mmHg (required ≥24). None had all the three device-observers comparisons greater than 5 mmHg for systolic and diastolic blood pressure. The AVITA wrist blood pressure monitor BPM17 has passed the requirements of the International Protocol revision 2010, and hence can be recommended for home use in adults.

  3. Clinical observations on the effect of carotid artery occlusion on cerebral blood flow mapped by xenon computed tomography and its correlation with carotid artery back pressure

    International Nuclear Information System (INIS)

    Steed, D.L.; Webster, M.W.; DeVries, E.J.; Jungreis, C.A.; Horton, J.A.; Sehkar, L.; Yonas, H.

    1990-01-01

    Xenon computed tomographic cerebral blood flow mapping was correlated with internal carotid artery stump pressures and clinical neurologic assessment during temporary internal carotid artery occlusion. One hundred fourteen patients with skull base tumors or intracranial aneurysms potentially requiring carotid resection or ligation underwent angiography, xenon CT cerebral blood flow mapping, and internal carotid artery blood pressure monitoring. The internal carotid artery was then temporarily occluded with a balloon catheter, stump pressure was measured through the catheter, and the xenon CT cerebral blood flow mapping was repeated. Adequate xenon CT cerebral blood flow was defined as greater than 30 cc/100 gm/min. All patients had normal xenon CT cerebral blood flow before internal carotid artery occlusion. During internal carotid artery occlusion, xenon CT cerebral blood flow was found to be normal (group I, 40 patients), globally reduced but still within the normal range (group II, 50 patients), or low in the distribution of the ipsilateral middle cerebral artery (group III, 13 patients). With balloon occlusion, an immediate neurologic deficit developed in 11 patients (9%) requiring deflation of the balloon preceding xenon CT cerebral blood flow measurement (group IV). In group I internal carotid artery blood pressure was 128 mm Hg. (range 85 to 171 mm Hg) with stump pressure 86 mm Hg (range 46 to 125 mm Hg). In group II internal carotid artery blood pressure was 130 mm Hg. (range 78 to 199 mm Hg), with stump pressure 86 mm Hg (range 31 to 150 mm Hg)

  4. [Development of a continuous blood pressure monitoring and recording system].

    Science.gov (United States)

    Zhang, Yang; Li, Yong; Gao, Shumei; Song, Yilin

    2012-09-01

    A small experimental system is constructed with working principle of continuous blood pressure monitoring based on the volume compensation method. The preliminary experimental results show that the system can collect blood pressure signals at the radial artery effectively. The digital PID algorithm can track the variation of blood pressure. And the accuracy of continuous blood pressure detecting achieve the level of same kind of product.

  5. First-order approximation for the pressure-flow relationship of spontaneously contracting lymphangions.

    Science.gov (United States)

    Quick, Christopher M; Venugopal, Arun M; Dongaonkar, Ranjeet M; Laine, Glen A; Stewart, Randolph H

    2008-05-01

    To return lymph to the great veins of the neck, it must be actively pumped against a pressure gradient. Mean lymph flow in a portion of a lymphatic network has been characterized by an empirical relationship (P(in) - P(out) = -P(p) + R(L)Q(L)), where P(in) - P(out) is the axial pressure gradient and Q(L) is mean lymph flow. R(L) and P(p) are empirical parameters characterizing the effective lymphatic resistance and pump pressure, respectively. The relation of these global empirical parameters to the properties of lymphangions, the segments of a lymphatic vessel bounded by valves, has been problematic. Lymphangions have a structure like blood vessels but cyclically contract like cardiac ventricles; they are characterized by a contraction frequency (f) and the slopes of the end-diastolic pressure-volume relationship [minimum value of resulting elastance (E(min))] and end-systolic pressure-volume relationship [maximum value of resulting elastance (E(max))]. Poiseuille's law provides a first-order approximation relating the pressure-flow relationship to the fundamental properties of a blood vessel. No analogous formula exists for a pumping lymphangion. We therefore derived an algebraic formula predicting lymphangion flow from fundamental physical principles and known lymphangion properties. Quantitative analysis revealed that lymph inertia and resistance to lymph flow are negligible and that lymphangions act like a series of interconnected ventricles. For a single lymphangion, P(p) = P(in) (E(max) - E(min))/E(min) and R(L) = E(max)/f. The formula was tested against a validated, realistic mathematical model of a lymphangion and found to be accurate. Predicted flows were within the range of flows measured in vitro. The present work therefore provides a general solution that makes it possible to relate fundamental lymphangion properties to lymphatic system function.

  6. Validation of the SEJOY BP-1307 upper-arm blood pressure monitor for home blood pressure monitoring according to the European Society of Hypertension International Protocol revision 2010.

    Science.gov (United States)

    Lei, Lei; Chen, Yi; Chen, Qi; Li, Yan; Wang, Ji-Guang

    2017-12-01

    The present study aimed to evaluate the accuracy of the automated oscillometric upper-arm blood pressure monitor SEJOY BP-1307 (also called JOYTECH DBP-1307) for home blood pressure monitoring according to the International Protocol of the European Society of Hypertension revision 2010. Systolic and diastolic blood pressures were sequentially measured in 33 adult Chinese individuals (13 women, 45.1 years of mean age) using a mercury sphygmomanometer (two observers) and the SEJOY BP-1307 device (one supervisor). Ninety-nine pairs of comparisons were obtained from 33 participants for judgments in two parts with three grading phases. The average±SD of the device-observer differences was 0.2±4.1 and -1.7±4.7 mmHg for systolic and diastolic blood pressure, respectively. The SEJOY BP-1307 device achieved the criteria in both part 1 and part 2 of the validation study. The SEJOY upper-arm blood pressure monitor BP-1307 has passed the requirements of the International Protocol revision 2010, and hence can be recommended for home use in adults.

  7. Effect of flow rate and temperature on transmembrane blood pressure drop in an extracorporeal artificial lung.

    Science.gov (United States)

    Park, M; Costa, E L V; Maciel, A T; Barbosa, E V S; Hirota, A S; Schettino, G de P; Azevedo, L C P

    2014-11-01

    Transmembrane pressure drop reflects the resistance of an artificial lung system to blood transit. Decreased resistance (low transmembrane pressure drop) enhances blood flow through the oxygenator, thereby, enhancing gas exchange efficiency. This study is part of a previous one where we observed the behaviour and the modulation of blood pressure drop during the passage of blood through artificial lung membranes. Before and after the induction of multi-organ dysfunction, the animals were instrumented and analysed for venous-venous extracorporeal membrane oxygenation, using a pre-defined sequence of blood flows. Blood flow and revolutions per minute (RPM) of the centrifugal pump varied in a linear fashion. At a blood flow of 5.5 L/min, pre- and post-pump blood pressures reached -120 and 450 mmHg, respectively. Transmembrane pressures showed a significant spread, particularly at blood flows above 2 L/min; over the entire range of blood flow rates, there was a positive association of pressure drop with blood flow (0.005 mmHg/mL/minute of blood flow) and a negative association of pressure drop with temperature (-4.828 mmHg/(°Celsius). These associations were similar when blood flows of below and above 2000 mL/minute were examined. During its passage through the extracorporeal system, blood is exposed to pressure variations from -120 to 450 mmHg. At high blood flows (above 2 L/min), the drop in transmembrane pressure becomes unpredictable and highly variable. Over the entire range of blood flows investigated (0-5500 mL/min), the drop in transmembrane pressure was positively associated with blood flow and negatively associated with body temperature. © The Author(s) 2014.

  8. Turbulent jet diffusion flame length evolution with cross flows in a sub-pressure atmosphere

    International Nuclear Information System (INIS)

    Wang, Qiang; Hu, Longhua; Zhang, Xiaozheng; Zhang, Xiaolei; Lu, Shouxiang; Ding, Hang

    2015-01-01

    Highlights: • Quantifying turbulent jet diffusion flame length with cross flows. • Unique data revealed for a sub-atmospheric pressure. • Non-dimensional global correlation proposed for flame trajectory-line length. - Abstract: This paper investigates the evolution characteristics of turbulent jet diffusion flame (flame trajectory-line length, flame height in vertical jet direction) with increasing cross flows in a sub-pressure (64 kPa) atmosphere. The combined effect of cross flow and a special sub-pressure atmosphere condition is revealed, where no data is available in the literatures. Experiments are carried out with a wind tunnel built specially in Lhasa city (altitude: 3650 m; pressure: 64 kPa) and in Hefei city (altitude: 50 m; pressure: 100 kPa), using nozzles with diameter of 3 mm, 4 mm and 5 mm and propane as fuel. It is found that, as cross flow air speed increases from zero, the flame trajectory-line length firstly decreases and then becomes almost stable (for relative small nozzle, 3 mm in this study) or increases (for relative large nozzle, 4 mm and 5 mm in this study) beyond a transitional critical cross flow air speed in normal pressure, however decreases monotonically until being blown-out in the sub-pressure atmosphere. The flame height in jet direction decreases monotonically with cross air flow speed and then reaches a steady value in both pressures. For the transitional state of flame trajectory-line length with increasing cross air flow speed, the corresponding critical cross flow air speed is found to be proportional to the fuel jet velocity, meanwhile independent of nozzle diameter. Correlation models are proposed for the flame height in jet direction and the flame trajectory-line length for both ambient pressures, which are shown to be in good agreement with the experimental results.

  9. Pressure distribution over tube surfaces of tube bundle subjected to two phase cross flow

    International Nuclear Information System (INIS)

    Sim, Woo Gun

    2013-01-01

    Two phase vapor liquid flows exist in many shell and tube heat exchangers such as condensers, evaporators and nuclear steam generators. To understand the fluid dynamic forces acting on a structure subjected to a two phase flow, it is essential to obtain detailed information about the characteristics of a two phase flow. The characteristics of a two phase flow and the flow parameters were introduced, and then, an experiment was performed to evaluate the pressure loss in the tube bundles and the fluid dynamic force acting on the cylinder owing to the pressure distribution. A two phase flow was pre mixed at the entrance of the test section, and the experiments were undertaken using a normal triangular array of cylinders subjected to a two phase cross flow. The pressure loss along the flow direction in the tube bundles was measured to calculate the two phase friction multiplier, and the multiplier was compared with the analytical value. Furthermore, the circular distributions of the pressure on the cylinders were measured. Based on the distribution and the fundamental theory of two phase flow, the effects of the void fraction and mass flux per unit area on the pressure coefficient and the drag coefficient were evaluated. The drag coefficient was calculated by integrating the measured pressure coefficient and the drag coefficient were evaluated. The drag coefficient was calculated by integrating the measured pressure on the tube by a numerical method. It was found that for low mass fluxes, the measured two phase friction multipliers agree well with the analytical results, and good agreement for the effect of the void fraction on the drag coefficients, as calculated by the measured pressure distributions, is shown qualitatively, as compared to the existing experimental results

  10. Magnetohydrodynamic pressure drop and flow balancing of liquid metal flow in a prototypic fusion blanket manifold

    Science.gov (United States)

    Rhodes, Tyler J.; Smolentsev, Sergey; Abdou, Mohamed

    2018-05-01

    Understanding magnetohydrodynamic (MHD) phenomena associated with the flow of electrically conducting fluids in complex geometry ducts subject to a strong magnetic field is required to effectively design liquid metal (LM) blankets for fusion reactors. Particularly, accurately predicting the 3D MHD pressure drop and flow distribution is important. To investigate these topics, we simulate a LM MHD flow through an electrically non-conducting prototypic manifold for a wide range of flow and geometry parameters using a 3D MHD solver, HyPerComp incompressible MHD solver for arbitrary geometry. The reference manifold geometry consists of a rectangular feeding duct which suddenly expands such that the duct thickness in the magnetic field direction abruptly increases by a factor rexp. Downstream of the sudden expansion, the LM is distributed into several parallel channels. As a first step in qualifying the flow, a magnitude of the curl of the induced Lorentz force was used to distinguish between inviscid, irrotational core flows and boundary and internal shear layers where inertia and/or viscous forces are important. Scaling laws have been obtained which characterize the 3D MHD pressure drop and flow balancing as a function of the flow parameters and the manifold geometry. Associated Hartmann and Reynolds numbers in the computations were ˜103 and ˜101-103, respectively, while rexp was varied from 4 to 12. An accurate model for the pressure drop was developed for the first time for inertial-electromagnetic and viscous-electromagnetic regimes based on 96 computed cases. Analysis shows that flow balance can be improved by lengthening the distance between the manifold inlet and the entrances of the parallel channels by utilizing the effect of flow transitioning to a quasi-two-dimensional state in the expansion region of the manifold.

  11. Pressure grouting of fractured basalt flows

    International Nuclear Information System (INIS)

    Shaw, P.; Weidner, J.; Phillips, S.; Alexander, J.

    1996-04-01

    This report describes a field trial of pressure grouting in basalt and the results of subsequent coring and permeability measurement activities. The objective was to show that the hydraulic conductivity of fractured basalt bedrock can be significantly reduced by pressure injection of cementitious materials. The effectiveness of the pressure grout procedure was evaluated by measuring the change in the hydraulic conductivity of the bedrock. The extent of grout penetration was established by analyzing postgrout injection drilling chips for the presence of a tracer in the grout and also by examining cores of the treated basalt. Downhole radar mapping was used to establish major lava flow patterns and follow water movement during a surface infiltration test. A site called Box Canyon, which is located northwest of the INEL, was chosen for this study due to the similarity of this surface outcrop geology to that of the underlying bedrock fracture system found at the Radioactive Waste Management Complex. This study showed that hydraulic conductivity of basalt can be reduced through pressure grouting of cementitious material

  12. Pressure grouting of fractured basalt flows

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, P.; Weidner, J.; Phillips, S.; Alexander, J.

    1996-04-01

    This report describes a field trial of pressure grouting in basalt and the results of subsequent coring and permeability measurement activities. The objective was to show that the hydraulic conductivity of fractured basalt bedrock can be significantly reduced by pressure injection of cementitious materials. The effectiveness of the pressure grout procedure was evaluated by measuring the change in the hydraulic conductivity of the bedrock. The extent of grout penetration was established by analyzing postgrout injection drilling chips for the presence of a tracer in the grout and also by examining cores of the treated basalt. Downhole radar mapping was used to establish major lava flow patterns and follow water movement during a surface infiltration test. A site called Box Canyon, which is located northwest of the INEL, was chosen for this study due to the similarity of this surface outcrop geology to that of the underlying bedrock fracture system found at the Radioactive Waste Management Complex. This study showed that hydraulic conductivity of basalt can be reduced through pressure grouting of cementitious material.

  13. Monitoring of Intracranial Pressure During Intracranial Endoscopy

    Directory of Open Access Journals (Sweden)

    Rajeev Kumar

    2013-08-01

    Full Text Available Background: Intracranial endoscopy is a minimum invasive procedure, which reduces trauma to the brain, is cost-effective, and carries a shortened hospital stay with an improved postoperative outcome. Objective: To monitor intracranial pressure changes during intracranial endoscopy among children and adults under general anesthesia/sedation, and to compare the intracranial pressure changes between children and adults receiving general anesthesia and among adults receiving general anesthesia and sedation. Methods: The present cross-sectional study was conducted in one of the tertiary care hospitals of Lucknow. This was carried out in the department of neurosurgery from January 2008 to December 2008. Patients who were not fit for general anesthesia received local anesthesia under sedation. Patients participating in the study were divided into three groups. Intracranial pressure was recorded at specific intervals. Parametric data were subjected to statistical analysis using a student\\s t test. Result: A total of 70 patients were undergoing intracranial endoscopy under general anesthesia during the study period. In both groups A and B, intracranial pressure increases the maximum during inflation of the balloon. In group C, all the variations in ICP were found to be statistically significant. In the comparison of intracranial pressure changes between groups A and B, no significant difference was found. All correlations in the comparison of groups B and C were found to be statistically significant (p< 0.001. Conclusion: There is a need for continuous intraoperative monitoring of ICP intracranial endoscopy, because ICP increases in various stages of the procedure, which can be detrimental to the perfusion of the brain. [Arch Clin Exp Surg 2013; 2(4.000: 240-245

  14. Modeling steam pressure under martian lava flows

    Science.gov (United States)

    Dundas, Colin M.; Keszthelyi, Laszlo P.

    2013-01-01

    Rootless cones on Mars are a valuable indicator of past interactions between lava and water. However, the details of the lava–water interactions are not fully understood, limiting the ability to use these features to infer new information about past water on Mars. We have developed a model for the pressurization of a dry layer of porous regolith by melting and boiling ground ice in the shallow subsurface. This model builds on previous models of lava cooling and melting of subsurface ice. We find that for reasonable regolith properties and ice depths of decimeters, explosive pressures can be reached. However, the energy stored within such lags is insufficient to excavate thick flows unless they draw steam from a broader region than the local eruption site. These results indicate that lag pressurization can drive rootless cone formation under favorable circumstances, but in other instances molten fuel–coolant interactions are probably required. We use the model results to consider a range of scenarios for rootless cone formation in Athabasca Valles. Pressure buildup by melting and boiling ice under a desiccated lag is possible in some locations, consistent with the expected distribution of ice implanted from atmospheric water vapor. However, it is uncertain whether such ice has existed in the vicinity of Athabasca Valles in recent history. Plausible alternative sources include surface snow or an aqueous flood shortly before the emplacement of the lava flow.

  15. Remote query measurement of pressure, fluid-flow velocity, and humidity using magnetoelastic thick-film sensors

    Science.gov (United States)

    Grimes, C. A.; Kouzoudis, D.

    2000-01-01

    Free-standing magnetoelastic thick-film sensors have a characteristic resonant frequency that can be determined by monitoring the magnetic flux emitted from the sensor in response to a time varying magnetic field. This property allows the sensors to be monitored remotely without the use of direct physical connections, such as wires, enabling measurement of environmental parameters from within sealed, opaque containers. In this work, we report on application of magnetoelastic sensors to measurement of atmospheric pressure, fluid-flow velocity, temperature, and mass load. Mass loading effects are demonstrated by fabrication of a remote query humidity sensor, made by coating the magnetoelastic thick film with a thin layer of solgel deposited Al2O3 that reversibly changes mass in response to humidity. c2000 Elsevier Science S.A. All rights reserved.

  16. Monitoring of Intracranial Pressure in Meningitis.

    Science.gov (United States)

    Depreitere, Bart; Bruyninckx, Dominike; Güiza, Fabian

    2016-01-01

    The literature on intracranial pressure (ICP) monitoring in meningitis is limited to case reports and a handful of descriptive series. The aim of this study is to investigate relationships among ICP, cerebral perfusion pressure (CPP), and outcome in meningitis and to identify whether ICP affected clinical decisions. Between 1999 and 2011, a total of 17 patients with meningitis underwent ICP monitoring at the University Hospitals Leuven. Charts were reviewed for clinical history, ICP/CPP data, imaging findings, and Glasgow Outcome Scale score. Univariate correlations were computed for outcome and ICP/CPP variables, computed tomography characteristics, and Corticosteroid Randomization After Significant Head Injury outcome model variables. Treatment decisions were assessed regarding whether or not they were based on ICP. At drain placement, Glasgow Coma Scale scores showed a median of 8 (range 3-12). Six of 17 patients had either one or two nonreactive pupils. Significant correlations with outcome were found for the highest documented ICP value (r = -0.70), the number of episodes when CPP meningitis high ICP and low CPP represent secondary insults. The poor condition of the patients illustrates that the level of suspicion for increased ICP in meningitis may not be high enough.

  17. Pressure modulation algorithm to separate cerebral hemodynamic signals from extracerebral artifacts.

    Science.gov (United States)

    Baker, Wesley B; Parthasarathy, Ashwin B; Ko, Tiffany S; Busch, David R; Abramson, Kenneth; Tzeng, Shih-Yu; Mesquita, Rickson C; Durduran, Turgut; Greenberg, Joel H; Kung, David K; Yodh, Arjun G

    2015-07-01

    We introduce and validate a pressure measurement paradigm that reduces extracerebral contamination from superficial tissues in optical monitoring of cerebral blood flow with diffuse correlation spectroscopy (DCS). The scheme determines subject-specific contributions of extracerebral and cerebral tissues to the DCS signal by utilizing probe pressure modulation to induce variations in extracerebral blood flow. For analysis, the head is modeled as a two-layer medium and is probed with long and short source-detector separations. Then a combination of pressure modulation and a modified Beer-Lambert law for flow enables experimenters to linearly relate differential DCS signals to cerebral and extracerebral blood flow variation without a priori anatomical information. We demonstrate the algorithm's ability to isolate cerebral blood flow during a finger-tapping task and during graded scalp ischemia in healthy adults. Finally, we adapt the pressure modulation algorithm to ameliorate extracerebral contamination in monitoring of cerebral blood oxygenation and blood volume by near-infrared spectroscopy.

  18. Single and two-phase flow pressure drop for CANFLEX bundle

    Energy Technology Data Exchange (ETDEWEB)

    Park, Joo Hwan; Jun, Ji Su; Suk, Ho Chun [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); Dimmick, G R; Bullock, D E [Atomic Energy of Canada Limited, Ontario (Canada)

    1999-12-31

    Friction factor and two-phase flow frictional multiplier for a CANFLEX bundle are newly developed and presented in this paper. CANFLEX as a 43-element fuel bundle has been developed jointly by AECL/KAERI to provide greater operational flexibility for CANDU reactor operators and designers. Friction factor and two-phase flow frictional multiplier have been developed by using the experimental data of pressure drops obtained from two series of Freon-134a (R-134a) CHF tests with a string of simulated CANFLEX bundles in a single phase and a two-phase flow conditions. The friction factor for a CANFLEX bundle is found to be about 20% higher than that of Blasius for a smooth circular pipe. The pressure drop predicted by using the new correlations of friction factor and two-phase frictional multiplier are well agreed with the experimental pressure drop data of CANFLEX bundle within {+-} 5% error. 11 refs., 5 figs. (Author)

  19. Pressure-driven occlusive flow of a confined red blood cell.

    Science.gov (United States)

    Savin, Thierry; Bandi, M M; Mahadevan, L

    2016-01-14

    When red blood cells (RBCs) move through narrow capillaries in the microcirculation, they deform as they flow. In pathophysiological processes such as sickle cell disease and malaria, RBC motion and flow are severely restricted. To understand this threshold of occlusion, we use a combination of experiment and theory to study the motion of a single swollen RBC through a narrow glass capillary of varying inner diameter. By tracking the movement of the squeezed cell as it is driven by a controlled pressure drop, we measure the RBC velocity as a function of the pressure gradient as well as the local capillary diameter, and find that the effective blood viscosity in this regime increases with both decreasing RBC velocity and tube radius by following a power-law that depends upon the length of the confined cell. Our observations are consistent with a simple elasto-hydrodynamic model and highlight the role of lateral confinement in the occluded pressure-driven slow flow of soft confined objects.

  20. Single and two-phase flow pressure drop for CANFLEX bundle

    Energy Technology Data Exchange (ETDEWEB)

    Park, Joo Hwan; Jun, Ji Su; Suk, Ho Chun [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); Dimmick, G. R.; Bullock, D. E. [Atomic Energy of Canada Limited, Ontario (Canada)

    1998-12-31

    Friction factor and two-phase flow frictional multiplier for a CANFLEX bundle are newly developed and presented in this paper. CANFLEX as a 43-element fuel bundle has been developed jointly by AECL/KAERI to provide greater operational flexibility for CANDU reactor operators and designers. Friction factor and two-phase flow frictional multiplier have been developed by using the experimental data of pressure drops obtained from two series of Freon-134a (R-134a) CHF tests with a string of simulated CANFLEX bundles in a single phase and a two-phase flow conditions. The friction factor for a CANFLEX bundle is found to be about 20% higher than that of Blasius for a smooth circular pipe. The pressure drop predicted by using the new correlations of friction factor and two-phase frictional multiplier are well agreed with the experimental pressure drop data of CANFLEX bundle within {+-} 5% error. 11 refs., 5 figs. (Author)

  1. Dynamic behaviour of high-pressure natural-gas flow in pipelines

    International Nuclear Information System (INIS)

    Gato, L.M.C.; Henriques, J.C.C.

    2005-01-01

    The aim of the present study is the numerical modelling of the dynamic behaviour of high-pressure natural-gas flow in pipelines. The numerical simulation was performed by solving the conservation equations, for one-dimensional compressible flow, using the Runge-Kutta discontinuous Galerkin method, with third-order approximation in space and time. The boundary conditions were imposed using a new weak formulation based on the characteristic variables. The occurrence of pressure oscillations in natural-gas pipelines was studied as a result of the compression wave originated by the rapid closure of downstream shut-off valves. The effect of the partial reflection of pressure waves was also analyzed in the transition between pipes of different cross-sectional areas

  2. Dynamic behaviour of high-pressure natural-gas flow in pipelines

    Energy Technology Data Exchange (ETDEWEB)

    Gato, L.M.C. [Department of Mechanical Engineering, Instituto Superior Tecnico, Technical University of Lisbon, Av. Rovisco Pais, 1049-001 Lisbon (Portugal)]. E-mail: lgato@mail.ist.utl.pt; Henriques, J.C.C. [Department of Mechanical Engineering, Instituto Superior Tecnico, Technical University of Lisbon, Av. Rovisco Pais, 1049-001 Lisbon (Portugal)]. E-mail: jcch@mail.ist.utl.pt

    2005-10-01

    The aim of the present study is the numerical modelling of the dynamic behaviour of high-pressure natural-gas flow in pipelines. The numerical simulation was performed by solving the conservation equations, for one-dimensional compressible flow, using the Runge-Kutta discontinuous Galerkin method, with third-order approximation in space and time. The boundary conditions were imposed using a new weak formulation based on the characteristic variables. The occurrence of pressure oscillations in natural-gas pipelines was studied as a result of the compression wave originated by the rapid closure of downstream shut-off valves. The effect of the partial reflection of pressure waves was also analyzed in the transition between pipes of different cross-sectional areas.

  3. Intensive versus conventional blood pressure monitoring in a general practice population. The Blood Pressure Reduction in Danish General Practice trial: a randomized controlled parallel group trial

    DEFF Research Database (Denmark)

    Klarskov, Pia; Bang, Lia E; Schultz-Larsen, Peter

    2018-01-01

    To compare the effect of a conventional to an intensive blood pressure monitoring regimen on blood pressure in hypertensive patients in the general practice setting. Randomized controlled parallel group trial with 12-month follow-up. One hundred and ten general practices in all regions of Denmark....... One thousand forty-eight patients with essential hypertension. Conventional blood pressure monitoring ('usual group') continued usual ad hoc blood pressure monitoring by office blood pressure measurements, while intensive blood pressure monitoring ('intensive group') supplemented this with frequent...... a reduction of blood pressure. Clinical Trials NCT00244660....

  4. Patients' blood pressure knowledge, perceptions and monitoring practices in community pharmacies.

    Science.gov (United States)

    Lam, Jennifer Y; Guirguis, Lisa M

    2010-07-01

    Hypertension is a modifiable risk factor for cardiovascular disease. Despite this, patients often cannot or inaccurately estimate their risk factors. IN ORDER TO IMPROVE PHARMACIST INTERVENTIONS, WE SOUGHT TO: 1) find out patients' knowledge about blood pressure (BP) and their self-monitoring behaviors and 2) identify the relationships between these two elements. Specifically, if evaluation of BP control were related to knowledge of one's BP level and self-monitoring habits, and if knowledge of one's target and BP level varied with monitoring habits. Final year pharmacy students were trained and interviewed patients in community pharmacies as a required exercise in their pharmacy clerkship. Each student recruited a convenience sample of 5-10 patients who were on hypertension medication, and surveyed them regarding their BP targets, recent BP levels as well as monthly and home BP monitoring practices. One third of the 449 patients interviewed were able to report a blood pressure target with 26% reporting a JNC 7 recognized target. Three quarters of patients who reported a blood pressure target were able to report a blood pressure level, with 12% being at their self-reported target. Roughly two thirds of patients perceived their BP to be "about right", and slightly less than a third thought it to be "high". Sixty percent of patients monitor their BP monthly, but less than 50% of patients practice home BP monitoring. This study along with others before it point to the knowledge and self-management gaps in patients with chronic conditions. Furthermore, pharmacy students were able to use a brief intervention to screen patients during routine care. Pharmacists can help improve patient understanding and promote increased self-management through regular BP monitoring.

  5. Validity and reliability of a novel slow cuff-deflation system for noninvasive blood pressure monitoring in patients with continuous-flow left ventricular assist device.

    Science.gov (United States)

    Lanier, Gregg M; Orlanes, Khristine; Hayashi, Yacki; Murphy, Jennifer; Flannery, Margaret; Te-Frey, Rosie; Uriel, Nir; Yuzefpolskaya, Melana; Mancini, Donna M; Naka, Yoshifumi; Takayama, Hiroo; Jorde, Ulrich P; Demmer, Ryan T; Colombo, Paolo C

    2013-09-01

    Doppler ultrasound is the clinical gold standard for noninvasive blood pressure (BP) measurement among continuous-flow left ventricular assist device patients. The relationship of Doppler BP to systolic BP (SBP) and mean arterial pressure (MAP) is uncertain and Doppler measurements require a clinic visit. We studied the relationship between Doppler BP and both arterial-line (A-line) SBP and MAP. Validity and reliability of the Terumo Elemano BP Monitor, a novel slow cuff-deflation device that could potentially be used by patients at home, were assessed. Doppler and Terumo BP measurements were made in triplicate among 60 axial continuous-flow left ventricular assist device (HeartMate II) patients (30 inpatients and 30 outpatients) at 2 separate exams (360 possible measurements). A-line measures were also obtained among inpatients. Mean absolute differences (MADs) and correlations were used to determine within-device reliability (comparison of second and third BP measures) and between-device validity. Bland-Altman plots assessed BP agreement between A-line, Doppler BP, and Terumo Elemano. Success rates for Doppler and Terumo Elemano were 100% and 91%. Terumo Elemano MAD for repeat SBP and MAP were 4.6±0.6 and 4.2±0.6 mm Hg; repeat Doppler BP MAD was 2.9±0.2 mm Hg. Mean Doppler BP was lower than A-line SBP by 4.1 (MAD=6.4±1.4) mm Hg and higher than MAP by 9.5 (MAD=11.0±1.2) mm Hg; Terumo Elemano underestimated A-line SBP by 0.3 (MAD=5.6±0.9) mm Hg and MAP by 1.7 (MAD=6.0±1.0) mm Hg. Doppler BP more closely approximates SBP than MAP. Terumo Elemano was successful, reliable, and valid when compared with A-line and Doppler.

  6. Recognition and measurement gas-liquid two-phase flow in a vertical concentric annulus at high pressures

    Science.gov (United States)

    Li, Hao; Sun, Baojiang; Guo, Yanli; Gao, Yonghai; Zhao, Xinxin

    2018-02-01

    The air-water flow characteristics under pressure in the range of 1-6 MPa in a vertical annulus were evaluated in this report. Time-resolved bubble rising velocity and void fraction were also measured using an electrical void fraction meter. The results showed that the pressure has remarkable effect on the density, bubble size and rise velocity of the gas. Four flow patterns (bubble, cap-bubble, cap-slug, and churn) were also observed instead of Taylor bubble at high pressure. Additionally, the transition process from bubble to cap-bubble was investigated at atmospheric and high pressures, respectively. The results revealed that the flow regime transition criteria for atmospheric pressure do not work at high pressure, hence a new flow regime transition model for annular flow channel geometry was developed to predict the flow regime transition, which thereafter exhibited high accuracy at high pressure condition.

  7. Pressure drop of magnetohydrodynamic two-phase annular flow in rectangular channel

    International Nuclear Information System (INIS)

    Kumamaru, Hiroshige; Fujiwara, Yoshiki; Ogita, Kenji

    1999-01-01

    Numerical calculations have been performed on magnetohydrodynamic (MHD) two-phase annular flow in a rectangular channel with a small aspect ratio, i.e.a small ratio of the channel side perpendicular to the applied magnetic field and the side parallel to the field. Results of the present calculation agree nearly with Inoue et al.'s experimental results in the region of large liquid Reynolds numbers and large Hartmann numbers. Calculation results also show that the pressure drop ratio, i.e. the ratio of pressure drop of two-phase flow to that of single-phase flow under the same liquid flow rate and applied magnetic field, becomes lower than ∼0.02 for conditions of a fusion reactor plant. (author)

  8. The impact of Indian Ocean high pressure system on rainfall and stream flow

    International Nuclear Information System (INIS)

    Rehman, S.; Nasir, H.; Zia, S.S.; Ansari, W.A.; Salam, K.; Tayyab, N.

    2012-01-01

    Centre of Action approach is very useful in getting insight of rainfall and stream flow variability of specific region. Hameed et al. showed that Inter-annual variability of Gulf Stream north wall is influenced by low Icelandic pressure system and has more statistically significant correlation than North Atlantic Oscillation (NAO) with longitude of Icelandic low. This study also aims to explore possible relationships between rainfall and stream flow in Collie river catchment in Southwest Western Australia (SWWA) with Indian Ocean high pressure dynamics. The relationship between rainfall and stream flow with Indian Ocean high pressure system have been investigated using correlation analysis for early winter season (MJJA), lag correlation for MJJA versus SOND rainfall and stream flow are also calculated and found significant at 95% confidence level. By investigating the relationship between COA indices with rainfall and stream flow over the period 1976-2008, significant correlations suggests that rainfall and stream flow in Collie river basin is strongly influenced by COA indices. Multiple correlations between rainfall and stream flow with Indian Ocean high pressure (IOHPS and IOHLN) is 0.7 and 0.6 respectively. Centers of Action (COA) indices explain 51% and 36% of rainfall and stream flow respectively. The correlation between rainfall and stream flow with IOHPS is -0.4 and -0.3 whereas, with IOHLN is -0.47 and -0.52 respectively. (author)

  9. Axisymmetric toroidal equilibrium with flow and anisotropic pressure

    International Nuclear Information System (INIS)

    Iacono, R.; Bondeson, A.; Troyon, F.; Gruber, R.

    1989-10-01

    Axisymmetric toroidal plasma equilibria with mass flows and anisotropic pressure are investigated. The equilibrium system is derived for a general functional form of the pressures, which includes both fluid models, such as the magnetohydrodynamic (MHD) and the double-adiabatic models, and Grad's guiding centre model. This allows for detailed comparisons between the models and clarifies how the 'first hyperbolic region', occurring in the fluid theory when the poloidal flow is of the order of the poloidal sound speed, can be eliminated in guiding centre theory. In the case of a pure toroidal rotation, macroscopic equations of state are derived from the guiding centre model, characterized by a parallel temperature that is constant on each magnetic surface and a perpendicular temperature that varies with the magnetic field. The outward centrifugal shifts of the magnetic axis and of the mass density profile, due to toroidal rotation, are increased by anisotropy. The guiding centre model shows that poloidal flow produces an inward shift of the density profile, in contrast with the MHD result. (author) 1 fig., 1 tab., 17 refs

  10. Development of optoelectronic monitoring system for ear arterial pressure waveforms

    Science.gov (United States)

    Sasayama, Satoshi; Imachi, Yu; Yagi, Tamotsu; Imachi, Kou; Ono, Toshirou; Man-i, Masando

    1994-02-01

    Invasive intra-arterial blood pressure measurement is the most accurate method but not practical if the subject is in motion. The apparatus developed by Wesseling et al., based on a volume-clamp method of Penaz (Finapres), is able to monitor continuous finger arterial pressure waveforms noninvasively. The limitation of Finapres is the difficulty in measuring the pressure of a subject during work that involves finger or arm action. Because the Finapres detector is attached to subject's finger, the measurements are affected by inertia of blood and hydrostatic effect cause by arm or finger motion. To overcome this problem, the authors made a detector that is attached to subject's ear and developed and optoelectronic monitoring systems for ear arterial pressure waveform (Earpres). An IR LEDs, photodiode, and air cuff comprised the detector. The detector was attached to a subject's ear, and the space adjusted between the air cuff and the rubber plate on which the LED and photodiode were positioned. To evaluate the accuracy of Earpres, the following tests were conducted with participation of 10 healthy male volunteers. The subjects rested for about five minutes, then performed standing and squatting exercises to provide wide ranges of systolic and diastolic arterial pressure. Intra- and inter-individual standard errors were calculated according to the method of van Egmond et al. As a result, average, the averages of intra-individual standard errors for earpres appeared small (3.7 and 2.7 mmHg for systolic and diastolic pressure respectively). The inter-individual standard errors for Earpres were about the same was Finapres for both systolic and diastolic pressure. The results showed the ear monitor was reliable in measuring arterial blood pressure waveforms and might be applicable to various fields such as sports medicine and ergonomics.

  11. Validation of the AVITA BPM15S wrist blood pressure monitor for home blood pressure monitoring according to the European Society of Hypertension International Protocol revision 2010.

    Science.gov (United States)

    Kang, Yuan-Yuan; Zeng, Wei-Fang; Zhang, Lu; Li, Yan; Wang, Ji-Guang

    2014-06-01

    The present study aimed to evaluate the accuracy of the automated oscillometric wrist blood pressure monitor AVITA BPM15S for home blood pressure monitoring according to the International Protocol revision 2010 of the European Society of Hypertension. Systolic and diastolic blood pressures were sequentially measured in 33 Chinese adults (15 women, mean age 51 years) using a mercury sphygmomanometer (two observers) and the AVITA BPM15S device (one supervisor). Ninety-nine pairs of comparisons were obtained from 33 participants for judgments in two parts with three grading phases. The AVITA BPM15S device achieved the targets in part 1 of the validation study. The number of absolute differences between the device and observers within 5, 10, and 15 mmHg were 85/99, 94/99, and 98/99, respectively, for systolic blood pressure, and 82/99, 96/99, and 98/99, respectively, for diastolic blood pressure. The device also achieved the criteria in part 2 of the validation study. Thirty-two and 28 participants for systolic and diastolic blood pressure, respectively, had at least two of the three device-observer differences within 5 mmHg (required ≥ 24). No participant had all of the three device-observer comparisons greater than 5 mmHg for systolic or diastolic blood pressure. The AVITA wrist blood pressure monitor BPM15S fulfilled the requirements of the International Protocol revision 2010 and hence can be recommended for home use in an adult population.

  12. Experimental and visual study on flow patterns and pressure drops in U-tubes

    International Nuclear Information System (INIS)

    Da Silva Lima, J. R.

    2011-01-01

    In single- and two-phase flow heat exchangers (in particular 'coils'), besides the straight tubes there are also many singularities, in particular the 180° return bends (also called return bends or U-bends). However, contrary to the literature concerning pressure drops and heat transfer in straight tubes, where many experimental data and predicting methods are available, only a limited number of studies concerning U-bends can be found. Neither reliable experimental data nor proven prediction methods are available. Indeed, flow structure, pressure drop and heat transfer in U-bends are an old unresolved design problem in the heat transfer industry. Thus, the present study aims at providing further insight on two-phase pressure drops and flows patterns in U-bends. Based on a new type of U-bend test section, an extensive experimental study was conducted. The experimental campaign covered five test sections with three internal diameters (7.8, 10.8 and 13.4 mm), five bend diameters (24.8, 31.7, 38.1, 54.8 and 66.1 mm), tested for three orientations (horizontal, vertical upflow and vertical downflow), two fluids (R134a and R410A), two saturation temperatures (5 and 10 °C) and mass velocities ranging from 150 to 1000 kg s -1 m -2 . The flow pattern observations identified were stratified-wavy, slug-stratified-wavy, intermittent, annular, dryout and mist flows. The effects of the U-bend on the flow patterns were also observed. A total of 5655 pressure drop data were measured at seven different locations in the test section ( straight tubes and U-bend) providing a total of almost 40,000 data points. The straight tube data were first used to improve the actual two-phase straight tube model of Moreno-Quibén and Thome. This updated model was then used to developed a two-phase U-bend pressure drop model. Based on a comparison between experimental and predicted values, it is concluded that the new two-phase frictional pressure drop model for U-bends successfully

  13. Ambulatory blood pressure monitoring and microalbuminuria in normotensive subjects with insulin-dependent diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Cohen Cesar Nissan

    2000-01-01

    Full Text Available OBJECTIVE: To assess the association between microalbuminuria with ambulatory blood pressure monitoring in normotensive individuals with insulin-dependent diabetes mellitus. METHODS: Thirty-seven patients underwent determination of the rate of urinary excretion of albumin through radioimmunoassay and ambulatory blood pressure monitoring. Their mean age was 26.5±6.7 years, and the mean duration of their disease was 8 (1-34 years. Microalbuminuria was defined as urinary excretion of albumin > or = 20 and 50% and diastolic pressure load > 30% during sleep was associated with microalbuminuria (p=0.008. The pressure drop during sleep did not differ between the groups. CONCLUSION: Microalbuminuric normotensive insulin-dependent diabetic patients show greater mean pressure value and pressure load during ambulatory blood pressure monitoring, and these variables correlate with urinary excretion of albumin.

  14. Air Flow and Pressure Drop Measurements Across Porous Oxides

    Science.gov (United States)

    Fox, Dennis S.; Cuy, Michael D.; Werner, Roger A.

    2008-01-01

    This report summarizes the results of air flow tests across eight porous, open cell ceramic oxide samples. During ceramic specimen processing, the porosity was formed using the sacrificial template technique, with two different sizes of polystyrene beads used for the template. The samples were initially supplied with thicknesses ranging from 0.14 to 0.20 in. (0.35 to 0.50 cm) and nonuniform backside morphology (some areas dense, some porous). Samples were therefore ground to a thickness of 0.12 to 0.14 in. (0.30 to 0.35 cm) using dry 120 grit SiC paper. Pressure drop versus air flow is reported. Comparisons of samples with thickness variations are made, as are pressure drop estimates. As the density of the ceramic material increases the maximum corrected flow decreases rapidly. Future sample sets should be supplied with samples of similar thickness and having uniform surface morphology. This would allow a more consistent determination of air flow versus processing parameters and the resulting porosity size and distribution.

  15. Use of intracranial pressure monitoring in bacterial meningitis

    DEFF Research Database (Denmark)

    Larsen, Lykke; Rom Poulsen, Frantz; Nielsen, Troels H

    2017-01-01

    BACKGROUND: The aim of this study was to evaluate the clinical outcome of patients with severe bacterial meningitis where intracranial pressure (ICP) monitoring has been performed. METHODS: A retrospective observational study including patients admitted 1st(.) January 2005 to 31st(.) December 2014...... CT scans with signs of elevated ICP. CONCLUSIONS: Patients with severe meningitis should be admitted to intensive care units and evaluated for ICP monitoring regardless of head CT findings....

  16. Novel Approach for Ensuring Increased Validity in Home Blood Pressure Monitoring

    DEFF Research Database (Denmark)

    Wagner, Stefan Rahr; Toftegaard, Thomas Skjødeberg; Bertelsen, Olav Wedege

    This paper proposes a novel technique to increase the validity of home blood pressure monitoring by using various sensor technologies as part of an intelligent environment platform in the home of the user. A range of recommendations exists on how to obtain a valid blood pressure but with the devi......This paper proposes a novel technique to increase the validity of home blood pressure monitoring by using various sensor technologies as part of an intelligent environment platform in the home of the user. A range of recommendations exists on how to obtain a valid blood pressure...

  17. Blood Pressure Home Monitoring in Hypertensive Patients Attending ...

    African Journals Online (AJOL)

    Blood Pressure Home Monitoring in Hypertensive Patients Attending a Tertiary ... Sixty percent of the patients were aged 50 - 69 years. ... Patients with high BP readings reported that they exercise more and reduced their daily salt intake.

  18. Monitoring of Underground Coal Gasification

    Energy Technology Data Exchange (ETDEWEB)

    Yang, X. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wagoner, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ramirez, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2012-08-31

    For efficient and responsible UCG operations, a UCG process must be monitored in the following three categories: 1) process parameters such as injection and product gas flow rates, temperature, pressure and syngas content and heating value; 2) geomechanical parameters, e.g., cavity and coal seam pressures, cavity development, subsidence and ground deformation; and 3) environmental parameters, e.g., groundwater chemistry and air quality. This report focuses on UCG monitoring with geophysical techniques that can contribute to monitoring of subsurface temperature, cavity development, burn front, subsidence and deformation.

  19. Primary flow meter for calibrating a sniffer test leak artefact by a pressure rise method

    Science.gov (United States)

    Arai, Kenta; Yoshida, Hajime

    2014-10-01

    Sniffer tests are used to locate leaks in equipment during operation. The sensitivity of a sniffer leak detector must be calibrated against a known gas flow to atmospheric pressure generated by a sniffer test leak artefact. We have developed a primary flow meter for calibrating gas flows to atmospheric pressure through the leak artefact. The flow meter is based on a pressure rise method and two chambers are used to measure the pressure rise with small uncertainty even at atmospheric pressure. The calibration range of the flow rate is 5 × 10-7 Pa m3 s-1 to 7 × 10-4 Pa m3 s-1 to atmospheric pressure at 23.0 °C with a minimum uncertainty of 1.4% (k = 2), as well as 4 × 10-8 Pa m3 s-1 to 5 × 10-4 Pa m3 s-1 to a vacuum at 23.0 °C. The long term stability of the flow meter was determined as 0.41% by repeated measurements of the conductance of the leak artefact. In case of the flow rate into a vacuum, the flow meter was successfully linked to the international reference value of CCM.P-K12 by a lab-internal comparison.

  20. Nonlinear vacuum gas flow through a short tube due to pressure and temperature gradients

    Energy Technology Data Exchange (ETDEWEB)

    Pantazis, Sarantis; Naris, Steryios; Tantos, Christos [Department of Mechanical Engineering, University of Thessaly, Pedion Areos, 38334 Volos (Greece); Valougeorgis, Dimitris, E-mail: diva@mie.uth.gr [Department of Mechanical Engineering, University of Thessaly, Pedion Areos, 38334 Volos (Greece); André, Julien; Millet, Francois; Perin, Jean Paul [Service des Basses Températures, UMR-E CEA/UJF-Grenoble 1, INAC, Grenoble, F-38054 (France)

    2013-10-15

    The flow of a rarefied gas through a tube due to both pressure and temperature gradients has been studied numerically. The main objective is to investigate the performance of a mechanical vacuum pump operating at low temperatures in order to increase the pumped mass flow rate. This type of pump is under development at CEA-Grenoble. The flow is modelled by the Shakhov kinetic model equation, which is solved by the discrete velocity method. Results are presented for certain geometry and flow parameters. Since according to the pump design the temperature driven flow is in the opposite direction than the main pressure driven flow, it has been found that for the operating pressure range studied here the net mass flow rate through the pump may be significantly reduced.

  1. Nonlinear vacuum gas flow through a short tube due to pressure and temperature gradients

    International Nuclear Information System (INIS)

    Pantazis, Sarantis; Naris, Steryios; Tantos, Christos; Valougeorgis, Dimitris; André, Julien; Millet, Francois; Perin, Jean Paul

    2013-01-01

    The flow of a rarefied gas through a tube due to both pressure and temperature gradients has been studied numerically. The main objective is to investigate the performance of a mechanical vacuum pump operating at low temperatures in order to increase the pumped mass flow rate. This type of pump is under development at CEA-Grenoble. The flow is modelled by the Shakhov kinetic model equation, which is solved by the discrete velocity method. Results are presented for certain geometry and flow parameters. Since according to the pump design the temperature driven flow is in the opposite direction than the main pressure driven flow, it has been found that for the operating pressure range studied here the net mass flow rate through the pump may be significantly reduced

  2. Phase separation and pressure drop of two-phase flow in vertical manifolds

    International Nuclear Information System (INIS)

    Zetzmann, K.

    1982-01-01

    The splitting of a two-phase mass flow in a tube manifold results in a separation between liquid and gas phase. A study is presented of the phase distribution and the related two-phase pressure drop for vertical manifolds in the technically relevant geometry and flow parameter region of an air-water-flow. At the outlet changes in the gas/fluid-radio are observed which are proportional to this ratio at the inlet. The separation characteristic strongly depends on the massflow through the junction. Empirical equations are given to calculate the separation. Measuring the pressure drop at main- and secondary tube of the manifold the additional pressure drop can be obtained. If these results are related with the dynamic pressure at the inlet, two-phase resistance coefficients can be deduced, which may be tested by empirical relations. (orig.) [de

  3. Bridge pressure flow scour for clear water conditions

    Science.gov (United States)

    2009-10-01

    The equilibrium scour at a bridge caused by pressure flow with critical approach velocity in clear-water simulation conditions was studied both analytically and experimentally. The flume experiments revealed that (1) the measured equilibrium scour pr...

  4. Evaluation of the monitor cursor-line method for measuring pulmonary artery and central venous pressures.

    Science.gov (United States)

    Pasion, Editha; Good, Levell; Tizon, Jisebelle; Krieger, Staci; O'Kier, Catherine; Taylor, Nicole; Johnson, Jennifer; Horton, Carrie M; Peterson, Mary

    2010-11-01

    To determine if the monitor cursor-line feature on bedside monitors is accurate for measuring central venous and pulmonary artery pressures in cardiac surgery patients. Central venous and pulmonary artery pressures were measured via 3 methods (end-expiratory graphic recording, monitor cursor-line display, and monitor digital display) in a convenience sample of postoperative cardiac surgery patients. Pressures were measured twice during both mechanical ventilation and spontaneous breathing. Analysis of variance was used to determine differences between measurement methods and the percentage of monitor pressures that differed by 4 mm Hg or more from the measurement obtained from the graphic recording. Significance level was set at P less than .05. Twenty-five patients were studied during mechanical ventilation (50 measurements) and 21 patients during spontaneous breathing (42 measurements). Measurements obtained via the 3 methods did not differ significantly for either type of pressure (P > .05). Graphically recorded pressures and measurements obtained via the monitor cursor-line or digital display methods differed by 4 mm Hg or more in 4% and 6% of measurements, respectively, during mechanical ventilation and 4% and 11%, respectively, during spontaneous breathing. The monitor cursor-line method for measuring central venous and pulmonary artery pressures may be a reasonable alternative to the end-expiratory graphic recording method in hemodynamically stable, postoperative cardiac surgery patients. Use of the digital display on the bedside monitor may result in larger discrepancies from the graphically recorded pressures than when the cursor-line method is used, particularly in spontaneously breathing patients.

  5. Analysis of the pressure fields in a swirling annular jet flow

    NARCIS (Netherlands)

    Perçin, M.; Vanierschot, M.; van Oudheusden, B.W.

    2017-01-01

    In this paper, we investigate the flow structures and pressure fields of a free annular swirling jet flow undergoing vortex breakdown. The flow field is analyzed by means of time-resolved tomographic particle image velocimetry measurements, which enable the reconstruction of the three-dimensional

  6. Patients’ blood pressure knowledge, perceptions and monitoring practices in community pharmacies

    Directory of Open Access Journals (Sweden)

    Lam JY

    2010-09-01

    Full Text Available Hypertension is a modifiable risk factor for cardiovascular disease. Despite this, patients often cannot or inaccurately estimate their risk factors.Objectives: In order to improve pharmacist interventions, we sought to: 1 find out patients’ knowledge about blood pressure (BP and their self- monitoring behaviors and 2 identify the relationships between these two elements. Specifically, if evaluation of BP control were related to knowledge of one’s BP level and self-monitoring habits, and if knowledge of one’s target and BP level varied with monitoring habits. Methods: Final year pharmacy students were trained and interviewed patients in community pharmacies as a required exercise in their pharmacy clerkship. Each student recruited a convenience sample of 5-10 patients who were on hypertension medication, and surveyed them regarding their BP targets, recent BP levels as well as monthly and home BP monitoring practices. Results: One third of the 449 patients interviewed were able to report a blood pressure target with 26% reporting a JNC 7 recognized target. Three quarters of patients who reported a blood pressure target were able to report a blood pressure level, with 12% being at their self- reported target. Roughly two thirds of patients perceived their BP to be “about right”, and slightly less than a third thought it to be “high”. Sixty percent of patients monitor their BP monthly, but less than 50% of patients practice home BP monitoring. Conclusions: This study along with others before it point to the knowledge and self-management gaps in patients with chronic conditions. Furthermore, pharmacy students were able to use a brief intervention to screen patients during routine care. Pharmacists can help improve patient understanding and promote increased self-management through regular BP monitoring.

  7. Intensive versus conventional blood pressure monitoring in a general practice population. The Blood Pressure Reduction in Danish General Practice trial: a randomized controlled parallel group trial.

    Science.gov (United States)

    Klarskov, Pia; Bang, Lia E; Schultz-Larsen, Peter; Gregers Petersen, Hans; Benee Olsen, David; Berg, Ronan M G; Abrahamsen, Henrik; Wiinberg, Niels

    2018-01-17

    To compare the effect of a conventional to an intensive blood pressure monitoring regimen on blood pressure in hypertensive patients in the general practice setting. Randomized controlled parallel group trial with 12-month follow-up. One hundred and ten general practices in all regions of Denmark. One thousand forty-eight patients with essential hypertension. Conventional blood pressure monitoring ('usual group') continued usual ad hoc blood pressure monitoring by office blood pressure measurements, while intensive blood pressure monitoring ('intensive group') supplemented this with frequent home blood pressure monitoring and 24-hour ambulatory blood pressure monitoring. Mean day- and night-time systolic and diastolic 24-hour ambulatory blood pressure. Change in systolic and diastolic office blood pressure and change in cardiovascular risk profile. Of the patients, 515 (49%) were allocated to the usual group, and 533 (51%) to the intensive group. The reductions in day- and night-time 24-hour ambulatory blood pressure were similar (usual group: 4.6 ± 13.5/2.8 ± 82 mmHg; intensive group: 5.6 ± 13.0/3.5 ± 8.2 mmHg; P = 0.27/P = 0.20). Cardiovascular risk scores were reduced in both groups at follow-up, but more so in the intensive than in the usual group (P = 0.02). An intensive blood pressure monitoring strategy led to a similar blood pressure reduction to conventional monitoring. However, the intensive strategy appeared to improve patients' cardiovascular risk profile through other effects than a reduction of blood pressure. Clinical Trials NCT00244660. © The Author 2018. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  8. Validation of the AVITA BPM63S upper arm blood pressure monitor for home blood pressure monitoring according to the European Society of Hypertension International Protocol revision 2010.

    Science.gov (United States)

    Kang, Yuan-Yuan; Zeng, Wei-Fang; Liu, Ming; Li, Yan; Wang, Ji-Guang

    2014-02-01

    The present study aimed to evaluate the accuracy of the AVITA BPM63S upper arm blood pressure monitor for home blood pressure monitoring according to the International Protocol of the European Society of Hypertension revision 2010. Systolic and diastolic blood pressures were sequentially measured in 33 adult Chinese (14 women, mean age of 47 years) using a mercury sphygmomanometer (two observers) and the AVITA BPM63S device (one supervisor). Ninety-nine pairs of comparisons were obtained from 33 participants for judgments in two parts with three grading phases. All the blood pressure requirements were fulfilled. The AVITA BPM63S device achieved the targets in part 1 of the validation study. The number of absolute differences between device and observers within 5, 10, and 15 mmHg was 68/99, 89/99, and 96/99, respectively, for systolic blood pressure, and 75/99, 95/99, and 97/99, respectively, for diastolic blood pressure. The device also achieved the criteria in part 2 of the validation study. Twenty-four and 25 participants for systolic and diastolic blood pressure, respectively, had at least two of the three device-observers differences within 5 mmHg (required ≥24). One and two participants for systolic and diastolic blood pressure, respectively, had all three device-observers differences greater than 5 mmHg. The AVITA BPM63S automated oscillometric upper arm blood pressure monitor has passed the requirements of the International Protocol revision 2010, and hence can be recommended for blood pressure measurement at home in adults.

  9. Velocity-pressure correlation measurements in complex free shear flows

    International Nuclear Information System (INIS)

    Naka, Yoshitsugu; Obi, Shinnosuke

    2009-01-01

    Simultaneous measurements of fluctuating velocity and pressure were performed in various turbulent free shear flows including a turbulent mixing layer and the wing-tip vortex trailing from a NACA0012 half-wing. Two different methods for fluctuating static pressure measurement were considered: a direct method using a miniature Pitot tube and an indirect method where static pressure was calculated from total pressure. The pressure obtained by either of these methods was correlated with the velocity measured by an X-type hot-wire probe. The results from these two techniques agreed with each other in the turbulent mixing layer. In the wing-tip vortex case, however, some discrepancies were found, although overall characteristics of the pressure-related statistics were adequately captured by both methods.

  10. Cerebral Blood Flow Autoregulation in Sepsis for the Intensivist: Why Its Monitoring May Be the Future of Individualized Care.

    Science.gov (United States)

    Goodson, Carrie M; Rosenblatt, Kathryn; Rivera-Lara, Lucia; Nyquist, Paul; Hogue, Charles W

    2018-02-01

    Cerebral blood flow (CBF) autoregulation maintains consistent blood flow across a range of blood pressures (BPs). Sepsis is a common cause of systemic hypotension and cerebral dysfunction. Guidelines for BP management in sepsis are based on historical concepts of CBF autoregulation that have now evolved with the availability of more precise technology for its measurement. In this article, we provide a narrative review of methods of monitoring CBF autoregulation, the cerebral effects of sepsis, and the current knowledge of CBF autoregulation in sepsis. Current guidelines for BP management in sepsis are based on a goal of maintaining mean arterial pressure (MAP) above the lower limit of CBF autoregulation. Bedside tools are now available to monitor CBF autoregulation continuously. These data reveal that individual BP goals determined from CBF autoregulation monitoring are more variable than previously expected. In patients undergoing cardiac surgery with cardiopulmonary bypass, for example, the lower limit of autoregulation varied between a MAP of 40 to 90 mm Hg. Studies of CBF autoregulation in sepsis suggest patients frequently manifest impaired CBF autoregulation, possibly a result of BP below the lower limit of autoregulation, particularly in early sepsis or with sepsis-associated encephalopathy. This suggests that the present consensus guidelines for BP management in sepsis may expose some patients to both cerebral hypoperfusion and cerebral hyperperfusion, potentially resulting in damage to brain parenchyma. The future use of novel techniques to study and clinically monitor CBF autoregulation could provide insight into the cerebral pathophysiology of sepsis and offer more precise treatments that may improve functional and cognitive outcomes for survivors of sepsis.

  11. Estimation of Flow Channel Parameters for Flowing Gas Mixed with Air in Atmospheric-pressure Plasma Jets

    Science.gov (United States)

    Yambe, Kiyoyuki; Saito, Hidetoshi

    2017-12-01

    When the working gas of an atmospheric-pressure non-equilibrium (cold) plasma flows into free space, the diameter of the resulting flow channel changes continuously. The shape of the channel is observed through the light emitted by the working gas of the atmospheric-pressure plasma. When the plasma jet forms a conical shape, the diameter of the cylindrical shape, which approximates the conical shape, defines the diameter of the flow channel. When the working gas flows into the atmosphere from the inside of a quartz tube, the gas mixes with air. The molar ratio of the working gas and air is estimated from the corresponding volume ratio through the relationship between the diameter of the cylindrical plasma channel and the inner diameter of the quartz tube. The Reynolds number is calculated from the kinematic viscosity of the mixed gas and the molar ratio. The gas flow rates for the upper limit of laminar flow and the lower limit of turbulent flow are determined by the corresponding Reynolds numbers estimated from the molar ratio. It is confirmed that the plasma jet length and the internal plasma length associated with strong light emission increase with the increasing gas flow rate until the rate for the upper limit of laminar flow and the lower limit of turbulent flow, respectively. Thus, we are able to explain the increasing trend in the plasma lengths with the diameter of the flow channel and the molar ratio by using the cylindrical approximation.

  12. STUDY OF IDENTIFICATION OF TWO-PHASE FLOW PARAMETERS BY PRESSURE FLUCTUATION ANALYSIS

    Directory of Open Access Journals (Sweden)

    Ondrej Burian

    2016-12-01

    Full Text Available This paper deals with identification of parameters of simple pool boiling in a vertical rectangular channel by analysis of pressure fluctuation. In this work is introduced a small experimental facility about 9 kW power, which was used for simulation of pool boiling phenomena and creation of steam-water volume. Several pressure fluctuations measurements and differential pressure fluctuations measurements at warious were carried out. Main changed parameters were power of heaters and hydraulics resistance of channel internals. Measured pressure data was statistically analysed and compared with goal to find dependencies between parameters of two-phase flow and statistical properties of pressure fluctuation. At the end of this paper are summarized final results and applicability of this method for parameters determination of two phase flow for pool boiling conditions at ambient pressure.

  13. Effect of pulse pressure on borehole stability during shear swirling flow vibration cementing.

    Directory of Open Access Journals (Sweden)

    Zhihua Cui

    Full Text Available The shear swirling flow vibration cementing (SSFVC technique rotates the downhole eccentric cascade by circulating cementing fluid. It makes the casing eccentrically revolve at high speed around the borehole axis. It produces strong agitation action to the annulus fluid, makes it in the state of shear turbulent flow, and results in the formation of pulse pressure which affects the surrounding rock stress. This study was focused on 1 the calculation of the pulse pressure in an annular turbulent flow field based on the finite volume method, and 2 the analysis of the effect of pulse pressure on borehole stability. On the upside, the pulse pressure is conducive to enhancing the liquidity of the annulus fluid, reducing the fluid gel strength, and preventing the formation of fluid from channeling. But greater pulse pressure may cause lost circulation and even formation fracturing. Therefore, in order to ensure smooth cementing during SSFVC, the effect of pulse pressure should be considered when cementing design.

  14. State of art report for critical flow model to analyze a break flow in pressurizer of integral type reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Yeon Moon; Lee, D. J.; Yoon, J. H.; Kim, J. P.; Kim, H. Y

    1999-03-01

    At a critical flow condition, the flow rate can't exceed a maximum value for given upstream conditions and the limited flow rate is called as a critical flow rate. The phenomena of critical flow occur at the discharge of a single phase gas or subcooled water through nozzles and pipes. Among the previous researches on critical flow, many accurate correlations on pressure, temperature and flow rate are represented for the single phase gas. However, for the two phase critical flow, the results of previous work showed that there was a large discrepancy between the analytical and experimental data and the data were in agreement for the limited thermodynamic conditions. Thus, further studies are required to enhance the two phase critical flow model. In the integral reactor, the critical flows of nitrogen gas and subcooled water are expected for the break of gas cylinder pipeline connected to the pressurizer. It requires that the inlet shape of the pipe and the nitrogen gas effect should be considered for the critical flow of integral reactor. The nitrogen gas exist in the pressurizer may affect the flow rate of primary coolant, which has been considered only for a few previous researches. Thus, the evaluation of the effect of the nitrogen on the critical flow gas should be preceded for the proper analysis of the critical flow in the integral reactor. In this report, not only the essences of previous work on critical flow were investigated and summarized but also the effect of nitrogen gas and the inlet shape of the pipe on the critical flow were also investigated. (author)

  15. State of art report for critical flow model to analyze a break flow in pressurizer of integral type reactor

    International Nuclear Information System (INIS)

    Kang, Yeon Moon; Lee, D. J.; Yoon, J. H.; Kim, J. P.; Kim, H. Y.

    1999-03-01

    At a critical flow condition, the flow rate can't exceed a maximum value for given upstream conditions and the limited flow rate is called as a critical flow rate. The phenomena of critical flow occur at the discharge of a single phase gas or subcooled water through nozzles and pipes. Among the previous researches on critical flow, many accurate correlations on pressure, temperature and flow rate are represented for the single phase gas. However, for the two phase critical flow, the results of previous work showed that there was a large discrepancy between the analytical and experimental data and the data were in agreement for the limited thermodynamic conditions. Thus, further studies are required to enhance the two phase critical flow model. In the integral reactor, the critical flows of nitrogen gas and subcooled water are expected for the break of gas cylinder pipeline connected to the pressurizer. It requires that the inlet shape of the pipe and the nitrogen gas effect should be considered for the critical flow of integral reactor. The nitrogen gas exist in the pressurizer may affect the flow rate of primary coolant, which has been considered only for a few previous researches. Thus, the evaluation of the effect of the nitrogen on the critical flow gas should be preceded for the proper analysis of the critical flow in the integral reactor. In this report, not only the essences of previous work on critical flow were investigated and summarized but also the effect of nitrogen gas and the inlet shape of the pipe on the critical flow were also investigated. (author)

  16. Comparison of under-pressure and over-pressure pulse tests conducted in low-permeability basalt horizons at the Hanford Site, Washington State

    International Nuclear Information System (INIS)

    Thorne, P.D.; Spane, F.A. Jr.

    1984-10-01

    Over-pressure pulse tests (pressurized slug tests have been widely used by others for hydraulic characterization of low-permeability ( -8 m/sec) rock formations. Recent field studies of low-permeability basalt horizons at the Hanford Site, Washington, indicate that the under-pressure pulse technique is also a viable test method for hydraulic characterization studies. For over-pressure pulse tests, fluid within the test system is rapidly pressurized and the associated pressure decay is monitored as compressed fluid within the test system expands and flows into the test formation. Under-pressure pulse tests are conducted in a similar manner by abruptly decreasing the pressure of fluid within the test system, and monitoring the associated increase in pressure as fluid flows from the formation into the test system. Both pulse test methods have been used in conjunction with other types of tests to determine the hydraulic properties of selected low-permeability basalt horizons at Hanford test sites. Results from both pulse test methods generally provide comparable estimates of hydraulic properties and are in good agreement with those from other tests

  17. Noninvasive arterial blood pressure waveforms in patients with continuous-flow left ventricular assist devices.

    Science.gov (United States)

    Martina, Jerson R; Westerhof, Berend E; de Jonge, Nicolaas; van Goudoever, Jeroen; Westers, Paul; Chamuleau, Steven; van Dijk, Diederik; Rodermans, Ben F M; de Mol, Bas A J M; Lahpor, Jaap R

    2014-01-01

    Arterial blood pressure and echocardiography may provide useful physiological information regarding cardiac support in patients with continuous-flow left ventricular assist devices (cf-LVADs). We investigated the accuracy and characteristics of noninvasive blood pressure during cf-LVAD support. Noninvasive arterial pressure waveforms were recorded with Nexfin (BMEYE, Amsterdam, The Netherlands). First, these measurements were validated simultaneously with invasive arterial pressures in 29 intensive care unit patients. Next, the association between blood pressure responses and measures derived by echocardiography, including left ventricular end-diastolic dimensions (LVEDDs), left ventricular end-systolic dimensions (LVESDs), and left ventricular shortening fraction (LVSF) were determined during pump speed change procedures in 30 outpatients. Noninvasive arterial blood pressure waveforms by the Nexfin monitor slightly underestimated invasive measures during cf-LVAD support. Differences between noninvasive and invasive measures (mean ± SD) of systolic, diastolic, mean, and pulse pressures were -7.6 ± 5.8, -7.0 ± 5.2, -6.9 ± 5.1, and -0.6 ± 4.5 mm Hg, respectively (all blood pressure responses did not correlate with LVEDD, LVESD, or LVSF, while LVSF correlated weakly with both pulse pressure (r = 0.24; p = 0.005) and (dP(art)/dt)max (r = 0.25; p = 0.004). The dicrotic notch in the pressure waveform was a better predictor of aortic valve opening (area under the curve [AUC] = 0.87) than pulse pressure (AUC = 0.64) and (dP(art)/dt)max (AUC = 0.61). Patients with partial support rather than full support at 9,000 rpm had a significant change in systolic pressure, pulse pressure, and (dP(art)/dt)max during ramp studies, while echocardiographic measures did not change. Blood pressure measurements by Nexfin were reliable and may thereby act as a compliment to the assessment of the cf-LVAD patient.

  18. Control-rod, pressure and flow-induced accident and transient analysis of a direct-cycle, supercritical-pressure, light-water-cooled fast breeder reactor

    International Nuclear Information System (INIS)

    Kitoh, Kazuaki; Koshizuka, Seiichi; Oka, Yoshiaki

    1996-01-01

    The features of the direct-cycle, supercritical-pressure, light-water-cooled fast breeder reactor (SCFBR) are high thermal efficiency and simple reactor system. The safety principle is basically the same as that of an LWR since it is a water-cooled reactor. Maintaining the core flow is the basic safety requirement of the reactor, since its coolant system is the one through type. The transient behaviors at control rod, pressure and flow-induced abnormalities are analyzed and presented in this paper. The results of flow-induced transients of SCFBR were reported at ICONE-3, though pressure change was neglected. The change of fuel temperature distribution is also considered for the analysis of the rapid reactivity-induced transients such as control rod withdrawal. Total loss of flow and pump seizure are analyzed as the accidents. Loss of load, control rod withdrawal from the normal operation, loss of feedwater heating, inadvertent start of an auxiliary feedwater pump, partial loss of coolant flow and loss of external power are analyzed as the transients. The behavior of the flow-induced transients is not so much different from the analyses assuming constant pressure. Fly wheels should be equipped with the feedwater pumps to prolong the coast-down time more than 10s and to cope with the total loss of flow accident. The coolant density coefficient of the SCFBR is less than one tenth of a BWR in which the recirculation flow is used for the power control. The over pressurization transients at the loss of load is not so severe as that of a BWR. The power reaches 120%. The minimum deterioration heat flux ratio (MDHFR) and the maximum pressure are sufficiently lower than the criteria; MDHFR above 1.0 and pressure ratio below 1.10 of 27.5 MPa, maximum pressure for operation. Among the reactivity abnormalities, the control rod withdrawal transient from the normal operation is analyzed

  19. Condition monitoring through advanced sensor and computational technology

    International Nuclear Information System (INIS)

    Kim, Jung Taek; Hur, S.; Seong, S. H.; Hwang, Il Soon; Lee, Joon Hyun; You, Jun; Lee, Sang Jung

    2004-01-01

    In order to successfully implement the extended-life operation plan of the nuclear power plant (NPP), predictive maintenance based on on-line monitoring of deteriorated components becomes highly important. In this work, we present progresses in the development of an advanced monitoring system to detect the health condition on check valve failures and pipe wall-thinning phenomena. The failures of check valves have resulted in significant maintenance efforts, on occasion, have resulted in water hammer, over-pressurization of low-pressure systems, and damage to flow system components. Pipe wall-thinning is usually caused by Flow-Accelerated Corrosion (FAC) under the undesirable combination of water chemistry, flow velocity and material composition. A piping elbow in the moisture separator/reheater drain line on the secondary waterside of a PWR is chosen as a monitoring target

  20. A study on impulsive sound attenuation for a high-pressure blast flow field

    International Nuclear Information System (INIS)

    Kang, Kuk Jeong; Ko, Sung Ho; Lee, Dong Soo

    2008-01-01

    The present work addresses a numerical study on impulsive sound attenuation for a complex high-pressure blast flow field; these characteristics are generated by a supersonic propellant gas flow through a shock tube into an ambient environment. A numerical solver for analyzing the high pressure blast flow field is developed in this study. From numerical simulations, wave dynamic processes (which include a first precursor shock wave, a second main propellant shock wave, and interactions in the muzzle blasts) are simulated and discussed. The pressure variation of the blast flow field is analyzed to evaluate the effect of a silencer. A live firing test is also performed to evaluate four different silencers. The results of this study will be helpful in understanding blast wave and in designing silencers

  1. A study on impulsive sound attenuation for a high-pressure blast flow field

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Kuk Jeong [Agency for Defence Development, Daejeon (Korea, Republic of); Ko, Sung Ho; Lee, Dong Soo [Chungnam National University, Daejeon (Korea, Republic of)

    2008-01-15

    The present work addresses a numerical study on impulsive sound attenuation for a complex high-pressure blast flow field; these characteristics are generated by a supersonic propellant gas flow through a shock tube into an ambient environment. A numerical solver for analyzing the high pressure blast flow field is developed in this study. From numerical simulations, wave dynamic processes (which include a first precursor shock wave, a second main propellant shock wave, and interactions in the muzzle blasts) are simulated and discussed. The pressure variation of the blast flow field is analyzed to evaluate the effect of a silencer. A live firing test is also performed to evaluate four different silencers. The results of this study will be helpful in understanding blast wave and in designing silencers

  2. Estimation of brachial artery volume flow by duplex ultrasound imaging predicts dialysis access maturation.

    Science.gov (United States)

    Ko, Sae Hee; Bandyk, Dennis F; Hodgkiss-Harlow, Kelley D; Barleben, Andrew; Lane, John

    2015-06-01

    This study validated duplex ultrasound measurement of brachial artery volume flow (VF) as predictor of dialysis access flow maturation and successful hemodialysis. Duplex ultrasound was used to image upper extremity dialysis access anatomy and estimate access VF within 1 to 2 weeks of the procedure. Correlation of brachial artery VF with dialysis access conduit VF was performed using a standardized duplex testing protocol in 75 patients. The hemodynamic data were used to develop brachial artery flow velocity criteria (peak systolic velocity and end-diastolic velocity) predictive of three VF categories: low (800 mL/min). Brachial artery VF was then measured in 148 patients after a primary (n = 86) or revised (n = 62) upper extremity dialysis access procedure, and the VF category correlated with access maturation or need for revision before hemodialysis usage. Access maturation was conferred when brachial artery VF was >600 mL/min and conduit imaging indicated successful cannulation based on anatomic criteria of conduit diameter >5 mm and skin depth 800 mL/min was predicted when the brachial artery lumen diameter was >4.5 mm, peak systolic velocity was >150 cm/s, and the diastolic-to-systolic velocity ratio was >0.4. Brachial artery velocity spectra indicating VF 800 mL/min. Duplex testing to estimate brachial artery VF and assess the conduit for ease of cannulation can be performed in 5 minutes during the initial postoperative vascular clinic evaluation. Estimation of brachial artery VF using the duplex ultrasound, termed the "Fast, 5-min Dialysis Duplex Scan," facilitates patient evaluation after new or revised upper extremity dialysis access procedures. Brachial artery VF correlates with access VF measurements and has the advantage of being easier to perform and applicable for forearm and also arm dialysis access. When brachial artery velocity spectra criteria confirm a VF >800 mL/min, flow maturation and successful hemodialysis are predicted if anatomic criteria

  3. Slug flow transitions in horizontal gas/liquid two-phase flows. Dependence on channel height and system pressure for air/water and steam/water two-phase flows

    International Nuclear Information System (INIS)

    Nakamura, Hideo

    1996-05-01

    The slug flow transitions and related phenomena for horizontal two-phase flows were studied for a better prediction of two-phase flows that typically appear during the reactor loss-of-coolant accidents (LOCAs). For better representation of the flow conditions experimentally, two large-scaled facility: TPTF for high-pressure steam/water two-phase flows and large duct test facility for air/water two-phase flows, were used. The visual observation of the flow using a video-probe was performed in the TPTF experiments for good understanding of the phenomena. The currently-used models and correlations based mostly on the small-scale low-pressure experiments were reviewed and improved based on these experimental results. The modified Taitel-Dukler model for prediction of transition into slug flow from wavy flow and the modified Steen-Wallis correlation for prediction of onset of liquid entrainment from the interfacial waves were obtained. An empirical correlation for the gas-liquid interfacial friction factor was obtained further for prediction of liquid levels at wavy flow. The region of slug flow regime that is generally under influences of the channel height and system pressure was predicted well when these models and correlations were applied together. (author). 90 refs

  4. Modified Beer-Lambert law for blood flow.

    Science.gov (United States)

    Baker, Wesley B; Parthasarathy, Ashwin B; Busch, David R; Mesquita, Rickson C; Greenberg, Joel H; Yodh, A G

    2014-11-01

    We develop and validate a Modified Beer-Lambert law for blood flow based on diffuse correlation spectroscopy (DCS) measurements. The new formulation enables blood flow monitoring from temporal intensity autocorrelation function data taken at single or multiple delay-times. Consequentially, the speed of the optical blood flow measurement can be substantially increased. The scheme facilitates blood flow monitoring of highly scattering tissues in geometries wherein light propagation is diffusive or non-diffusive, and it is particularly well-suited for utilization with pressure measurement paradigms that employ differential flow signals to reduce contributions of superficial tissues.

  5. A Modern Method to Monitor Office Blood Pressure

    Directory of Open Access Journals (Sweden)

    Emiliya Khazan

    2017-10-01

    Full Text Available The diagnosis and management of hypertension relies on accurate and precise blood pressure (BP measurements and monitoring techniques. Variability in traditional office based BP readings can contribute to misclassification and potential misdiagnosis of hypertension, leading to inappropriate treatment and possibly avoidable adverse drug events. Both home blood pressure monitoring (HBPM and 24-hour ambulatory blood pressure monitoring (ABPM can improve characterization of BP status over traditional office values and can predict cardiovascular morbidity and mortality risk; however, they are limited by availability and/or practical use in many situations. Available in-office blood pressure measuring methods include manual auscultation, automated oscillometric, and automated office blood pressure (AOBP devices. A strong correlation exists between AOBP and awake ABPM measurements and has been linked to better prediction of end-organ damage and white coat response compared to standard office BP methods. While AOBP does not provide nocturnal BP readings, it can be utilized in several outpatient settings, and has the capability to decrease utilization of ABPM, white coat effect, and improve optimization of cardiovascular assessment, evaluation, and therapeutic assessment in clinical practice. Hypertension affects over 80 million adults in the United States (US and is a major risk factor for cardiovascular morbidity and mortality [1]. The condition’s ubiquitous nature and broad impact potentially makes understanding the diagnosis and treatment of hypertension key elements of managing cardiovascular risk. Though much attention is paid to the treatment of hypertension, from 2009 to 2012, 45.9% of US patients with hypertension were uncontrolled [1]. Appreciating the aspects of proper assessment of blood pressure is crucial and creates the foundation for approaching hypertension management. Until recently, hypertension was defined as an appropriately

  6. Online Monitoring of Composite Overwrapped Pressure Vessels (COPV)

    DEFF Research Database (Denmark)

    Pereira, Gilmar Ferreira; Figueiredo, Joana; Faria, Hugo

    2015-01-01

    product development, design and optimization, as well as to minimize the risks and improve the public acceptance. Within the scope of developing different COPV models for a wide range of operating pressures and applications, optical fiber Bragg grating (FBG) sensors were embedded in the liner......Composite overwrapped pressure vessels (COPV) have been increasingly pointed to as the most effective solution for high pressure storage of liquid and gaseous fluids. Reasonably high stiffness-to-weight ratios make them suitable for both static and mobile applications. However, higher operating...... pressures are sought continuously, to get higher energy densities in such storage systems, and safety aspects become critical. Thus, reliable design and test procedures are required to reduce the risks of undesired and unpredicted failures. An in-service health monitoring system may contribute to a better...

  7. Influence of antihypertensive therapy on cerebral perfusion in patients with metabolic syndrome: relationship with cognitive function and 24-h arterial blood pressure monitoring.

    Science.gov (United States)

    Efimova, Nataliya Y; Chernov, Vladimir I; Efimova, Irina Y; Lishmanov, Yuri B

    2015-08-01

    To investigate the regional cerebral blood flow, cognitive function, and parameters of 24-h arterial blood pressure monitoring in patients with metabolic syndrome before and after combination antihypertensive therapy. The study involved 54 patients with metabolic syndrome (MetS) investigated by brain single-photon emission computed tomography, 24-h blood pressure monitoring (ABPM), and comprehensive neuropsychological testing before and after 24 weeks of combination antihypertensive therapy. Patients with metabolic syndrome had significantly poorer regional cerebral blood flow compared with control group: by 7% (P = 0.003) in right anterior parietal cortex, by 6% (P = 0.028) in left anterior parietal cortex, by 8% (P = 0.007) in right superior frontal lobe, and by 10% (P = 0.00002) and 7% (P = 0.006) in right and left temporal brain regions, correspondingly. The results of neuropsychological testing showed 11% decrease in mentation (P = 0.002), and 19% (P = 0.011) and 20% (P = 0.009) decrease in immediate verbal and visual memory in patients with MetS as compared with control group. Relationships between the indices of ABPM, cerebral perfusion, and cognitive function were found. Data showed an improvement of regional cerebral blood flow, ABPM parameters, and indicators of cognitive functions after 6 months of antihypertensive therapy in patients with MetS. The study showed the presence of diffuse disturbances in cerebral perfusion is associated with cognitive disorders in patients with metabolic syndrome. Combination antihypertensive treatment exerts beneficial effects on the 24-h blood pressure profile, increases cerebral blood flow, and improves cognitive function in patients with MetS. © 2015 John Wiley & Sons Ltd.

  8. Opportunities for Process Monitoring Techniques at Delayed Access Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Curtis, Michael M.; Gitau, Ernest TN; Johnson, Shirley J.; Schanfein, Mark; Toomey, Christopher

    2013-09-20

    Except for specific cases where the International Atomic Energy Agency (IAEA) maintains a continuous presence at a facility (such as the Japanese Rokkasho Reprocessing Plant), there is always a period of time or delay between the moment a State is notified or aware of an upcoming inspection, and the time the inspector actually enters the material balance area or facility. Termed by the authors as “delayed access,” this period of time between inspection notice and inspector entrance to a facility poses a concern. Delayed access also has the potential to reduce the effectiveness of measures applied as part of the Safeguards Approach for a facility (such as short-notice inspections). This report investigates the feasibility of using process monitoring to address safeguards challenges posed by delayed access at a subset of facility types.

  9. Resistive pressure sensors integrated with a Coriolis mass flow sensor

    NARCIS (Netherlands)

    Alveringh, Dennis; Schut, Thomas; Wiegerink, Remco J.; Sparreboom, Wouter; Lötters, Joost Conrad

    2017-01-01

    We report on a novel resistive pressure sensor that is completely integrated with a Coriolis mass flow sensor on one chip, without the need for extra fabrication steps or different materials. Two pressure sensors are placed in-line with the Coriolis sensor without requiring any changes to the fluid

  10. Liquid metal monitor

    International Nuclear Information System (INIS)

    Caldwell-Nichols, C.J.; Roach, P.F.

    1982-01-01

    A liquid metal monitor of the by-pass plugging meter kind described in British Patent 1,308,466, is further provided with a pump arranged to oppose flow through a by-pass thereby to provide a constant pressure difference across an orifice and improve the sensitivity of the instrument. The monitor estimates the impurity content in a liquid metal stream. (author)

  11. Cerebral pressure-flow relationship in lowlanders and natives at high altitude.

    Science.gov (United States)

    Smirl, Jonathan D; Lucas, Samuel J E; Lewis, Nia C S; duManoir, Gregory R; Dumanior, Gregory R; Smith, Kurt J; Bakker, Akke; Basnyat, Aperna S; Ainslie, Philip N

    2014-02-01

    We investigated if dynamic cerebral pressure-flow relationships in lowlanders are altered at high altitude (HA), differ in HA natives and after return to sea level (SL). Lowlanders were tested at SL (n=16), arrival to 5,050 m, after 2-week acclimatization (with and without end-tidal PO2 normalization), and upon SL return. High-altitude natives (n=16) were tested at 5,050 m. Testing sessions involved resting spontaneous and driven (squat-stand maneuvers at very low (VLF, 0.05 Hz) and low (LF, 0.10 Hz) frequencies) measures to maximize blood pressure (BP) variability and improve assessment of the pressure-flow relationship using transfer function analysis (TFA). Blood flow velocity was assessed in the middle (MCAv) and posterior (PCAv) cerebral arteries. Spontaneous VLF and LF phases were reduced and coherence was elevated with acclimatization to HA (Pflow coupling. However, when BP was driven, both the frequency- and time-domain metrics were unaltered and comparable with HA natives. Acute mountain sickness was unrelated to TFA metrics. In conclusion, the driven cerebral pressure-flow relationship (in both frequency and time domains) is unaltered at 5,050 m in lowlanders and HA natives. Our findings indicate that spontaneous changes in TFA metrics do not necessarily reflect physiologically important alterations in the capacity of the brain to regulate BP.

  12. Effects of adenosine on pressure-flow relationships in an in vitro model of compartment syndrome.

    Science.gov (United States)

    Shrier, I; Baratz, A; Magder, S

    1997-03-01

    Blood flow through skeletal muscle is best modeled with a vascular waterfall at the arteriolar level. Under these conditions, flow is determined by the difference between perfusion pressure (Pper) and the waterfall pressure (Pcrit), divided by the arterial resistance (Ra). By pump perfusing an isolated canine gastrocnemius muscle (n = 6) after it was placed within an airtight box, with and without adenosine infusion, we observed an interaction between the pressure surrounding a muscle (as occurs in compartment syndrome) and baseline vascular tone. We titrated adenosine concentration to double baseline flow. We measured Pcrit and Ra at box pressures (Pbox), which resulted in 100 (Pbox = 0), 90, 75, and 50% flow without adenosine; and 200, 180, 150, 100, and 50% flow with adenosine. Without adenosine, each 10% decline in flow was associated with a 5.7 mmHg increase in Pcrit (P 0.9). We conclude that increases in pressure surrounding a muscle limit flow primarily through changes in Pcrit with and without adenosine-induced vasodilation. The interaction between Pbox and adenosine with respect to Pcrit but not Ra suggests that Pbox affects the tone of the vessels responsible for Pcrit but not Ra.

  13. What is the relationship between free flow and pressure flow studies in women?

    Science.gov (United States)

    Duckett, Jonathan; Cheema, Katherine; Patil, Avanti; Basu, Maya; Beale, Sian; Wise, Brian

    2013-03-01

    The relationship between free flow (FFS) and pressure flow (PFS) voiding studies remains uncertain and the effect of a urethral catheter on flow rates has not been determined. The relationship between residuals obtained at FF and PFS has yet to be established. This was a prospective cohort study based on 474 consecutive women undergoing cystometry using different sized urethral catheters at different centres. FFS and PFS data were compared for different conditions and the relationship of residuals analysed for FFS and PFS. The null hypothesis was that urethral catheters do not produce an alteration in maximum flow rates for PFS and FF studies. Urethral catheterisation results in lower flow rates (p flows are corrected for voided volume (p flow rates are lower in women with DO than USI (p flow rates and vice versa. There was no significant difference between the mean residuals of the two groups (FFS vs PFS-two-tailed t = 0.54, p = 0.59). Positive residuals in FFS showed a good association with positive residuals in the PFS (r = 0.53, p flow rates. The relationship can be compared mathematically. The null hypothesis can be rejected.

  14. Influence of isoflurane on the diastolic pressure-flow relationship and critical occlusion pressure during arterial CABG surgery: a randomized controlled trial

    OpenAIRE

    Hinz, Jos?; Mansur, Ashham; Hanekop, Gerd G.; Weyland, Andreas; Popov, Aron F.; Schmitto, Jan D.; Gr?ne, Frank F. G.; Bauer, Martin; Kazmaier, Stephan

    2016-01-01

    The effects of isoflurane on the determinants of blood flow during Coronary Artery Bypass Graft (CABG) surgery are not completely understood. This study characterized the influence of isoflurane on the diastolic Pressure-Flow (P-F) relationship and Critical Occlusion Pressure (COP) during CABG surgery. Twenty patients undergoing CABG surgery were studied. Patients were assigned to an isoflurane or control group. Hemodynamic and flow measurements during CABG surgery were perf...

  15. Integrated cantilever-based flow sensors with tunable sensitivity for in-line monitoring of flow fluctuations in microfluidic systems

    DEFF Research Database (Denmark)

    Noeth, Nadine-Nicole; Keller, Stephan Sylvest; Boisen, Anja

    2014-01-01

    For devices such as bio-/chemical sensors in microfluidic systems, flow fluctuations result in noise in the sensor output. Here, we demonstrate in-line monitoring of flow fluctuations with a cantilever-like sensor integrated in a microfluidic channel. The cantilevers are fabricated in different...... is directly proportional to the flow rate fluctuations in the microfluidic channel. The SiN cantilevers show a detection limit below 1 nL/min and the thinnest SU-8 cantilevers a detection limit below 5 nL/min. Finally, the sensor is applied for in-line monitoring of flow fluctuations generated by external...

  16. Dynamic surface-pressure instrumentation for rods in parallel flow

    International Nuclear Information System (INIS)

    Mulcahy, T.M.; Lawrence, W.

    1979-01-01

    Methods employed and experience gained in measuring random fluid boundary layer pressures on the surface of a small diameter cylindrical rod subject to dense, nonhomogeneous, turbulent, parallel flow in a relatively noise-contaminated flow loop are described. Emphasis is placed on identification of instrumentation problems; description of transducer construction, mounting, and waterproofing; and the pretest calibration required to achieve instrumentation capable of reliable data acquisition

  17. An analytical evaluation for the pressure drop characteristics of bottom nozzle flow holes

    International Nuclear Information System (INIS)

    Yang, S. G.; Kim, H. J.; Lim, H. T.; Park, E. J.; Jeon, K. L.

    2002-01-01

    An analytical evaluation for the bottom nozzle flow holes was performed to find a best design concept in terms of pressure drop. For this analysis, Computational Fluid Dynamics (CFD), FLUENT 5.5, code was selected as an analytical evaluation tool. The applicability of CFD code was verified by benchmarking study with Vibration Investigation of Small-scale Test Assemblies (VISTA) test data in several flow conditions and typical flow hole shape. From this verification, the analytical data were benchmarked roughly within 17% to the VISTA test data. And, overall trend under various flow conditions looked very similar between both cases. Based on the evaluated results using CFD code, it is concluded that the deburring and multiple chamfer hole features at leading edge are the excellent design concept to decrease pressure drop across bottom nozzle plate. The deburring and multiple chamfer hole features at leading edge on the bottom nozzle plate have 12% and 17% pressure drop benefit against a single chamfer hole feature on the bottom nozzle plate, respectively. These design features are meaningful and applicable as a low pressure drop design concept of bottom nozzle for Pressurized Water Reactor (PWR) fuel assembly

  18. Studies on unsteady pressure fields in the region of separating and reattaching flows

    Science.gov (United States)

    Govinda Ram, H. S.; Arakeri, V. H.

    1990-12-01

    Experimental studies on the measurement of pressure fields in the region of separating and reattaching flows behind several two-dimensional fore-bodies and one axisymmetric body are reported. In particular, extensive measurements of mean pressure, surface pressure fluctuation, and pressure fluctuation within the flow were made for a series of two-dimensional fore-body shapes consisting of triangular nose with varying included angle. The measurements from different bodies are compared and one of the important findings is that the maximum values of rms pressure fluctuation levels in the shear layer approaching reattachment are almost equal to the maximum value of the surface fluctuation levels.

  19. Non-adiabatic pressure loss boundary condition for modelling turbocharger turbine pulsating flow

    International Nuclear Information System (INIS)

    Chiong, M.S.; Rajoo, S.; Romagnoli, A.; Costall, A.W.; Martinez-Botas, R.F.

    2015-01-01

    Highlights: • Bespoke non-adiabatic pressure loss boundary for pulse flow turbine modelling. • Predictions show convincing results against experimental and literature data. • Predicted pulse pressure propagation is in good agreement with literature data. • New methodology is time efficient and requires minimal geometrical inputs. - Abstract: This paper presents a simplified methodology of pulse flow turbine modelling, as an alternative over the meanline integrated methodology outlined in previous work, in order to make its application to engine cycle simulation codes much more straight forward. This is enabled through the development of a bespoke non-adiabatic pressure loss boundary to represent the turbine rotor. In this paper, turbocharger turbine pulse flow performance predictions are presented along with a comparison of computation duration against the previously established integrated meanline method. Plots of prediction deviation indicate that the mass flow rate and actual power predictions from both methods are highly comparable and are reasonably close to experimental data. However, the new boundary condition required significantly lower computational time and rotor geometrical inputs. In addition, the pressure wave propagation in this simplified unsteady turbine model at different pulse frequencies has also been found to be in agreement with data from the literature, thereby supporting the confidence in its ability to simulate the wave action encountered in turbine pulse flow operation

  20. Review on pressure sensors for structural health monitoring

    Science.gov (United States)

    Sikarwar, Samiksha; Satyendra; Singh, Shakti; Yadav, Bal Chandra

    2017-12-01

    This paper reports the state of art in a variety of pressure and the detailed study of various matrix based pressure sensors. The performances of the bridges, buildings, etc. are threatened by earthquakes, material degradations, and other environmental effects. Structural health monitoring (SHM) is crucial to protect the people and also for assets planning. This study is a contribution in developing the knowledge about self-sensing smart materials and structures for the construction industry. It deals with the study of self-sensing as well as mechanical and electrical properties of different matrices based on pressure sensors. The relationships among the compression, tensile strain, and crack length with electrical resistance change are also reviewed.

  1. A remote data access architecture for home-monitoring health-care applications.

    Science.gov (United States)

    Lin, Chao-Hung; Young, Shuenn-Tsong; Kuo, Te-Son

    2007-03-01

    With the aging of the population and the increasing patient preference for receiving care in their own homes, remote home care is one of the fastest growing areas of health care in Taiwan and many other countries. Many remote home-monitoring applications have been developed and implemented to enable both formal and informal caregivers to have remote access to patient data so that they can respond instantly to any abnormalities of in-home patients. The aim of this technology is to give both patients and relatives better control of the health care, reduce the burden on informal caregivers and reduce visits to hospitals and thus result in a better quality of life for both the patient and his/her family. To facilitate their widespread adoption, remote home-monitoring systems take advantage of the low-cost features and popularity of the Internet and PCs, but are inherently exposed to several security risks, such as virus and denial-of-service (DoS) attacks. These security threats exist as long as the in-home PC is directly accessible by remote-monitoring users over the Internet. The purpose of the study reported in this paper was to improve the security of such systems, with the proposed architecture aimed at increasing the system availability and confidentiality of patient information. A broker server is introduced between the remote-monitoring devices and the in-home PCs. This topology removes direct access to the in-home PC, and a firewall can be configured to deny all inbound connections while the remote home-monitoring application is operating. This architecture helps to transfer the security risks from the in-home PC to the managed broker server, on which more advanced security measures can be implemented. The pros and cons of this novel architecture design are also discussed and summarized.

  2. Surface pressure drag for hydrostatic two-layer flow over axisymmetric mountains

    Energy Technology Data Exchange (ETDEWEB)

    Leutbecher, M.

    2000-07-01

    The effect of partial reflections on surface pressure drag is investigated for hydrostatic gravity waves in two-layer flow with piecewise constant buoyancy frequency. The variation of normalized surface pressure drag with interface height is analyzed for axisymmetric mountains. The results are compared with the familiar solution for infinitely long ridges. The drag for the two-layer flow is normalized with the drag of one-layer flow, which has the buoyancy frequency of the lower layer. An analytical expression for the normalized drag of axisymmetric mountains is derived from linear theory of steady flow. Additionally, two-layer flow over finite-height axisymmetric mountains is simulated numerically for flow with higher stability in the upper layer. The temporal evolution of the surface pressure drag is examined in a series of experiments with different interface and mountain heights. The focus is on the linear regime and the nonlinear regime of nonbreaking gravity waves. The dispersion of gravity waves in flow over isolated mountains prevents that the entire wave spectrum is in resonance at the same interface height, which is the case in hydrostatic flow over infinitely long ridges. In consequence, the oscillation of the normalized drag with interface height is smaller for axisymmetric mountains than for infinitely long ridges. However, even for a reflection coefficient as low as 1/3 the drag of an axisymmetric mountain can be amplified by 50% and reduced by 40%. The nonlinear drag becomes steady in the numerical experiments in which no wave breaking occurs. The steady state nonlinear drag agrees quite well with the prediction of linear theory if the linear drag is computed for a slightly lowered interface. (orig.)

  3. Pressure loss in two-phase flow through a microchannel rod bundle

    International Nuclear Information System (INIS)

    Smith, A.C.; Hamm, L.L.; Qureshi, Z.; Steeper, T.J.

    1998-01-01

    The purpose of the microchannel rod bundle two-phase flow test described here was to provide data for benchmarking safety analyses for the accelerator production of tritium (APT). The objective was to obtain pressure loss data for a typical accelerator target rod bundle over a wide range of two-phase flow conditions. The test rod bundle assembly was fabricated for single-phase pressure drop tests conducted at Los Alamos National Laboratory (LANL) and subsequently used for the two-phase flow testing described here. The results for a typical case are given. These results fall generally in the slug flow regime for the horizontal flow results of Fukano and Kariyasaki for a 1.0-mm circular channel. Fukano and Kariyasaki found that surface tension effects were dominant in the 1-mm channel and report no churn regime. The results were also compared with the flow regime maps given by Triplett et al. for flow in discrete microchannels. Triplett employed both circular and trapezoidal channels, the latter to approximate the rod bundle interstitial flow channel shape. It was found that the rod bundle flow fell across the slug-to-churn flow regime transition reported by Triplett. This is consistent with the expectation that cross flow among channels would result in turbulent mixing and would suppress the formation of large discrete bubbles

  4. Frictional pressure drop of gas liquid two-phase flow in pipes

    International Nuclear Information System (INIS)

    Shannak, Benbella A.

    2008-01-01

    Experiments of air water two-phase flow frictional pressure drop of vertical and horizontal smooth and relatively rough pipes were conducted, respectively. The result demonstrated that the frictional pressure drop increases with increasing relative roughness of the pipe. However, the influence of the relative roughness becomes more evident at higher vapour quality and higher mass flux. A new prediction model for frictional pressure drop of two-phase flow in pipes is proposed. The model includes a new definition of the Reynolds number and the friction factor of two-phase flow. The proposed model fits the presented experimental data very well, for vertical, horizontal, smooth and rough pipes. Therefore, the reproductive accuracy of the model is tested on the experimental data existing in the open literature and compared with the most common models. The statistical comparison, based on the Friedel's Data-Bank containing of about 16,000 measured data, demonstrated that the proposed model is the best overall agreement with the data. The model was tested for a wide range of flow types, fluid systems, physical properties and geometrical parameters, typically encountered in industrial piping systems. Hence, calculating based on the new approach is sufficiently accurate for engineering purposes

  5. Inclusion of pressure and flow in the KITES MHD equilibrium code

    International Nuclear Information System (INIS)

    Raburn, Daniel; Fukuyama, Atsushi

    2013-01-01

    One of the simplest self-consistent models of a plasma is single-fluid magnetohydrodynamic (MHD) equilibrium with no bulk fluid flow under axisymmetry. However, both fluid flow and non-axisymmetric effects can significantly impact plasma equilibrium and confinement properties: in particular, fluid flow can produce profile pedestals, and non-axisymmetric effects can produce islands and stochastic regions. There exist a number of computational codes which are capable of calculating equilibria with arbitrary flow or with non-axisymmetric effects. Previously, a concept for a code to calculate MHD equilibria with flow in non-axisymmetric systems was presented, called the KITES (Kyoto ITerative Equilibrium Solver) code. Since then, many of the computational modules for the KITES code have been completed, and the work-in-progress KITES code has been used to calculate non-axisymmetric force-free equilibria. Additional computational modules are required to allow the KITES code to calculate equilibria with pressure and flow. Here, the authors report on the approaches used in developing these modules and provide a sample calculation with pressure. (author)

  6. Pressure drop and friction factor correlations of supercritical flow

    International Nuclear Information System (INIS)

    Fang Xiande; Xu Yu; Su Xianghui; Shi Rongrong

    2012-01-01

    Highlights: ► Survey and evaluation of friction factor models for supercritical flow. ► Survey of experimental study of supercritical flow. ► New correlation of friction factor for supercritical flow. - Abstract: The determination of the in-tube friction pressure drop under supercritical conditions is important to the design, analysis and simulation of transcritical cycles of air conditioning and heat pump systems, nuclear reactor cooling systems and some other systems. A number of correlations for supercritical friction factors have been proposed. Their accuracy and applicability should be examined. This paper provides a comprehensive survey of experimental investigations into the pressure drop of supercritical flow in the past decade and a comparative study of supercritical friction factor correlations. Our analysis shows that none of the existing correlations is completely satisfactory, that there are contradictions between the existing experimental results and thus more elaborate experiments are needed, and that the tube roughness should be considered. A new friction factor correlation for supercritical tube flow is proposed based on 390 experimental data from the available literature, including 263 data of supercritical R410A cooling, 45 data of supercritical R404A cooling, 64 data of supercritical carbon dioxide (CO 2 ) cooling and 18 data of supercritical R22 heating. Compared with the best existing model, the new correlation increases the accuracy by more than 10%.

  7. Changes in subcutaneous blood flow during locally applied negative pressure to the skin

    DEFF Research Database (Denmark)

    Skagen, K; Henriksen, O

    1983-01-01

    The effect of locally applied subatmospheric pressure on subcutaneous blood flow was studied in 12 healthy subjects. Blood flow was measured on the forearm by the local 133Xe wash-out technique. Air suction between 10 mmHg and 250 mmHg was applied to the skin. Subatmospheric pressure of 20 mm...

  8. Pressure from particle image velocimetry for convective flows: a Taylor’s hypothesis approach

    International Nuclear Information System (INIS)

    De Kat, R; Ganapathisubramani, B

    2013-01-01

    Taylor’s hypothesis is often applied in turbulent flow analysis to map temporal information into spatial information. Recent efforts in deriving pressure from particle image velocimetry (PIV) have proposed multiple approaches, each with its own weakness and strength. Application of Taylor’s hypothesis allows us to counter the weakness of an Eulerian approach that is described by de Kat and van Oudheusden (2012 Exp. Fluids 52 1089–106). Two different approaches of using Taylor’s hypothesis in determining planar pressure are investigated: one where pressure is determined from volumetric PIV data and one where pressure is determined from time-resolved stereoscopic PIV data. A performance assessment on synthetic data shows that application of Taylor’s hypothesis can improve determination of pressure from PIV data significantly compared with a time-resolved volumetric approach. The technique is then applied to time-resolved PIV data taken in a cross-flow plane of a turbulent jet (Ganapathisubramani et al 2007 Exp. Fluids 42 923–39). Results appear to indicate that pressure can indeed be obtained from PIV data in turbulent convective flows using the Taylor’s hypothesis approach, where there are no other methods to determine pressure. The role of convection velocity in determination of pressure is also discussed. (paper)

  9. Countercurrent Air-Water Flow in a Scale-Down Model of a Pressurizer Surge Line

    Directory of Open Access Journals (Sweden)

    Takashi Futatsugi

    2012-01-01

    Full Text Available Steam generated in a reactor core and water condensed in a pressurizer form a countercurrent flow in a surge line between a hot leg and the pressurizer during reflux cooling. Characteristics of countercurrent flow limitation (CCFL in a 1/10-scale model of the surge line were measured using air and water at atmospheric pressure and room temperature. The experimental results show that CCFL takes place at three different locations, that is, at the upper junction, in the surge line, and at the lower junction, and its characteristics are governed by the most dominating flow limitation among the three. Effects of inclination angle and elbows of the surge line on CCFL characteristics were also investigated experimentally. The effects of inclination angle on CCFL depend on the flow direction, that is, the effect is large for the nearly horizontal flow and small for the vertical flow at the upper junction. The presence of elbows increases the flow limitation in the surge line, whereas the flow limitations at the upper and lower junctions do not depend on the presence of elbows.

  10. Scaling of two-phase flow transients using reduced pressure system and simulant fluid

    International Nuclear Information System (INIS)

    Kocamustafaogullari, G.; Ishii, M.

    1987-01-01

    Scaling criteria for a natural circulation loop under single-phase flow conditions are derived. Based on these criteria, practical applications for designing a scaled-down model are considered. Particular emphasis is placed on scaling a test model at reduced pressure levels compared to a prototype and on fluid-to-fluid scaling. The large number of similarty groups which are to be matched between modell and prototype makes the design of a scale model a challenging tasks. The present study demonstrates a new approach to this clasical problen using two-phase flow scaling parameters. It indicates that a real time scaling is not a practical solution and a scaled-down model should have an accelerated (shortened) time scale. An important result is the proposed new scaling methodology for simulating pressure transients. It is obtained by considerung the changes of the fluid property groups which appear within the two-phase similarity parameters and the single-phase to two-phase flow transition prameters. Sample calculations are performed for modeling two-phase flow transients of a high pressure water system by a low-pressure water system or a Freon system. It is shown that modeling is possible for both cases for simulation pressure transients. However, simulation of phase change transitions is not possible by a reduced pressure water system without distortion in either power or time. (orig.)

  11. Wearable Beat to Beat Blood Pressure Monitor, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — A key component of NASA's human exploration programs is a system that monitors the health of the crew during space missions. The wearable beat-to-beat blood pressure...

  12. Pressure drop and stability of flow in Archimedean spiral tube with transverse corrugations

    Directory of Open Access Journals (Sweden)

    Đorđević Milan

    2016-01-01

    Full Text Available Isothermal pressure drop experiments were carried out for the steady Newtonian fluid flow in Archimedean spiral tube with transverse corrugations. Pressure drop correlations and stability criteria for distinguishing the flow regimes have been obtained in a continuous Reynolds number range from 150 to 15 000. The characterizing geometrical groups which take into account all the geometrical parameters of Archimedean spiral and corrugated pipe has been acquired. Before performing experiments over the Archimedean spiral, the corrugated straight pipe having high relative roughness e/d = 0.129 of approximately sinusoidal type was tested in order to obtain correlations for the Darcy friction factor. Insight into the magnitude of pressure loss in the proposed geometry of spiral solar receiver for different flow rates is important because of its effect upon the efficiency of the receiver. Although flow in spiral and corrugated geometries has the advantages of compactness and high heat transfer rates, the disadvantage of greater pressure drops makes hydrodynamic studies relevant. [Projekat Ministarstva nauke Republike Srbije, br. III 42006 i br. TR 33015

  13. Stochastic model to monitor mechanical vibrations in pressurized water reactors

    International Nuclear Information System (INIS)

    Shieh, D.J.; Upadhyaya, B.R.

    1984-01-01

    The feasibility of using neutron flux and core-exit temperature signals in PWRs for estimating core coolant flow velocity has been demonstrated using normal operational data from both the LOFT reactor and a commerical PWR. The LOFT analysis further showed that the core coolant velocity can be accurately monitored for various flow rates using the linear phase-frequency relationship in the frequency range 0.1 to 2 Hz. The development of the technique for monitoring core coolant velocity in PWRs provides a valuable alternative for flow measurement. Theoretical studies of core heat transfer in PWRs showed that the fluctuating heat sources have a dominating effect on the core-exit temperature compared to fluctuations of the coolant flow rate and core inlet coolant temperature. In the present analysis a detailed distributed parameter model of a PWR core was developed with the purpose of studying the following aspects of core coolant flow rate measurement: the mechanisms causing linear phase relationship between neutron flux and coolant temperature signals due to various perturbation sources; the effect of axial flux shape on the phase slope (or estimated transit delay time); and the relationship between transit delay time and effective distance of temperature noise propagation to maintain the flow velocity invariant

  14. Stability Improvement of High-Pressure-Ratio Turbocharger Centrifugal Compressor by Asymmetric Flow Control-Part I: Non-Axisymmetrical Flow in Centrifugal Compressor.

    Science.gov (United States)

    Yang, Mingyang; Zheng, Xinqian; Zhang, Yangjun; Bamba, Takahiro; Tamaki, Hideaki; Huenteler, Joern; Li, Zhigang

    2013-03-01

    This is Part I of a two-part paper documenting the development of a novel asymmetric flow control method to improve the stability of a high-pressure-ratio turbocharger centrifugal compressor. Part I focuses on the nonaxisymmetrical flow in a centrifugal compressor induced by the nonaxisymmetrical geometry of the volute while Part II describes the development of an asymmetric flow control method to avoid the stall on the basis of the characteristic of nonaxisymmetrical flow. To understand the asymmetries, experimental measurements and corresponding numerical simulation were carried out. The static pressure was measured by probes at different circumferential and stream-wise positions to gain insights about the asymmetries. The experimental results show that there is an evident nonaxisymmetrical flow pattern throughout the compressor due to the asymmetric geometry of the overhung volute. The static pressure field in the diffuser is distorted at approximately 90 deg in the rotational direction of the volute tongue throughout the diffuser. The magnitude of this distortion slightly varies with the rotational speed. The magnitude of the static pressure distortion in the impeller is a function of the rotational speed. There is a significant phase shift between the static pressure distributions at the leading edge of the splitter blades and the impeller outlet. The numerical steady state simulation neglects the aforementioned unsteady effects found in the experiments and cannot predict the phase shift, however, a detailed asymmetric flow field structure is obviously obtained.

  15. Bifurcation analysis of nephron pressure and flow regulation

    DEFF Research Database (Denmark)

    Barfred, Mikael; Mosekilde, Erik; Holstein-Rathlou, N.-H.

    1996-01-01

    One- and two-dimensional continuation techniques are applied to study the bifurcation structure of a model of renal flow and pressure control. Integrating the main physiological mechanisms by which the individual nephron regulates the incoming blood flow, the model describes the interaction between...... the tubuloglomerular feedback and the response of the afferent arteriole. It is shown how a Hopf bifurcation leads the system to perform self-sustained oscillations if the feedback gain becomes sufficiently strong, and how a further increase of this parameter produces a folded structure of overlapping period...

  16. Fine PM measurements: personal and indoor air monitoring.

    Science.gov (United States)

    Jantunen, M; Hänninen, O; Koistinen, K; Hashim, J H

    2002-12-01

    This review compiles personal and indoor microenvironment particulate matter (PM) monitoring needs from recently set research objectives, most importantly the NRC published "Research Priorities for Airborne Particulate Matter (1998)". Techniques and equipment used to monitor PM personal exposures and microenvironment concentrations and the constituents of the sampled PM during the last 20 years are then reviewed. Development objectives are set and discussed for personal and microenvironment PM samplers and monitors, for filter materials, and analytical laboratory techniques for equipment calibration, filter weighing and laboratory climate control. The progress is leading towards smaller sample flows, lighter, silent, independent (battery powered) monitors with data logging capacity to store microenvironment or activity relevant sensor data, advanced flow controls and continuous recording of the concentration. The best filters are non-hygroscopic, chemically pure and inert, and physically robust against mechanical wear. Semiautomatic and primary standard equivalent positive displacement flow meters are replacing the less accurate methods in flow calibration, and also personal sampling flow rates should become mass flow controlled (with or without volumetric compensation for pressure and temperature changes). In the weighing laboratory the alternatives are climatic control (set temperature and relative humidity), and mechanically simpler thermostatic heating, air conditioning and dehumidification systems combined with numerical control of temperature, humidity and pressure effects on flow calibration and filter weighing.

  17. A blood pressure monitor with robust noise reduction system under linear cuff inflation and deflation.

    Science.gov (United States)

    Usuda, Takashi; Kobayashi, Naoki; Takeda, Sunao; Kotake, Yoshifumi

    2010-01-01

    We have developed the non-invasive blood pressure monitor which can measure the blood pressure quickly and robustly. This monitor combines two measurement mode: the linear inflation and the linear deflation. On the inflation mode, we realized a faster measurement with rapid inflation rate. On the deflation mode, we realized a robust noise reduction. When there is neither noise nor arrhythmia, the inflation mode incorporated on this monitor provides precise, quick and comfortable measurement. Once the inflation mode fails to calculate appropriate blood pressure due to body movement or arrhythmia, then the monitor switches automatically to the deflation mode and measure blood pressure by using digital signal processing as wavelet analysis, filter bank, filter combined with FFT and Inverse FFT. The inflation mode succeeded 2440 measurements out of 3099 measurements (79%) in an operating room and a rehabilitation room. The new designed blood pressure monitor provides the fastest measurement for patient with normal circulation and robust measurement for patients with body movement or severe arrhythmia. Also this fast measurement method provides comfortableness for patients.

  18. Transition between trickle flow and pulse flow in a cocurrent gas-liquid trickle-bed reactor at elevated pressures

    NARCIS (Netherlands)

    Wammes, W.J.A.; Mechielsen, S.J.; Westerterp, K.R.

    1992-01-01

    The effect of reactor pressure in the range of 0.2–2.0 MPa on the transition between the trickle-flow and the pulse-flow regime has been investigated for the non-foaming water—nitrogen and aqueous 40% ethyleneglycol—nitrogen systems. Most models and flow charts which are all based on atmospheric

  19. Bayesian inference for heterogeneous caprock permeability based on above zone pressure monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Namhata, Argha; Small, Mitchell J.; Dilmore, Robert M.; Nakles, David V.; King, Seth

    2017-02-01

    The presence of faults/ fractures or highly permeable zones in the primary sealing caprock of a CO2 storage reservoir can result in leakage of CO2. Monitoring of leakage requires the capability to detect and resolve the onset, location, and volume of leakage in a systematic and timely manner. Pressure-based monitoring possesses such capabilities. This study demonstrates a basis for monitoring network design based on the characterization of CO2 leakage scenarios through an assessment of the integrity and permeability of the caprock inferred from above zone pressure measurements. Four representative heterogeneous fractured seal types are characterized to demonstrate seal permeability ranging from highly permeable to impermeable. Based on Bayesian classification theory, the probability of each fractured caprock scenario given above zone pressure measurements with measurement error is inferred. The sensitivity to injection rate and caprock thickness is also evaluated and the probability of proper classification is calculated. The time required to distinguish between above zone pressure outcomes and the associated leakage scenarios is also computed.

  20. Evaluation and performance enhancement of a pressure transducer under flows, waves, and a combination of flows and waves

    Digital Repository Service at National Institute of Oceanography (India)

    Joseph, A.; Desa, J.A.E.; Foden, P.; Taylor, K.; McKeown, J.; Desa, E.

    plate. This enhancement is likely to have been achieved because of the isolation of the pressure inlet from the separated flows and vortices generated by the transducer housing. Flow disturbances, generated by nearby solid structures, deteriorated...

  1. Physics design of fissile mass-flow monitoring system

    International Nuclear Information System (INIS)

    Mattingly, J.K.; March-Leuba, J.; Valentine, T.E.; Mihalczo, J.T.; Uckan, T.

    1997-01-01

    The system measures the flow rate and uranium-235 content in liquid or gas streams; it does not penetrate the process piping. A moderated fission neutron source is used to periodicially introduce a burst of thermal neutrons into the fluid stream to induce fission; delayed gamma emissions from the resulting fission fragments are detected by high-efficiency scintillators downstream of the neutron source. The fluid flow rate is measure from the time between initiation of the thermal neutron burst and detection of the fission product gamma emissions, and the U-235 content is inferred from the intensity of the gamma burst detected. Design of the fissile mass flow monitor requires satisfaction of several competing constraints. Efficient operation of the monitor requires that source-induced fission rate and detection efficiency be maximized while the source-induced background rate is simultaneoulsy minimized. Near optical nuclear design of the system was achieved using numerous Monte Carlo calculations and measurements. This paper addresses calculational aspects of the physics design for the system applied to UF 6 gas

  2. Pressure mapping with textile sensors for compression therapy monitoring.

    Science.gov (United States)

    Baldoli, Ilaria; Mazzocchi, Tommaso; Paoletti, Clara; Ricotti, Leonardo; Salvo, Pietro; Dini, Valentina; Laschi, Cecilia; Francesco, Fabio Di; Menciassi, Arianna

    2016-08-01

    Compression therapy is the cornerstone of treatment in the case of venous leg ulcers. The therapy outcome is strictly dependent on the pressure distribution produced by bandages along the lower limb length. To date, pressure monitoring has been carried out using sensors that present considerable drawbacks, such as single point instead of distributed sensing, no shape conformability, bulkiness and constraints on patient's movements. In this work, matrix textile sensing technologies were explored in terms of their ability to measure the sub-bandage pressure with a suitable temporal and spatial resolution. A multilayered textile matrix based on a piezoresistive sensing principle was developed, calibrated and tested with human subjects, with the aim of assessing real-time distributed pressure sensing at the skin/bandage interface. Experimental tests were carried out on three healthy volunteers, using two different bandage types, from among those most commonly used. Such tests allowed the trends of pressure distribution to be evaluated over time, both at rest and during daily life activities. Results revealed that the proposed device enables the dynamic assessment of compression mapping, with a suitable spatial and temporal resolution (20 mm and 10 Hz, respectively). In addition, the sensor is flexible and conformable, thus well accepted by the patient. Overall, this study demonstrates the adequacy of the proposed piezoresistive textile sensor for the real-time monitoring of bandage-based therapeutic treatments. © IMechE 2016.

  3. Effect of trailing edge ramp on cavity flow structures and pressure drag

    International Nuclear Information System (INIS)

    Pey, Yin Yin; Chua, Leok Poh; Siauw, Wei Long

    2014-01-01

    Highlights: • Trailing edge ramps were used to reduce unsteadiness and pressure drag of a cavity. • Proper Orthogonal Decomposition was used to educe the coherent structures. • The 30° ramp was successful in redistributing the energy content within the cavity. • The 30° ramp guides the flow smoothly out of the cavity, reducing flow impingement. • A substantial reduction of pressure drag was achieved by the 30° ramp. -- Abstract: The effects of trailing edge ramp modifications on time-averaged velocity and pressure distributions within a cavity with a length to depth ratio of 2, at a speed of 15 m/s were investigated. The ramp angles were varied at 30°, 45° and 60° and ramp heights were varied at 0.25 times and 0.5 times of cavity depth. The mean flow within the cavity differed significantly from the baseline case when ramp angle was 30° and 45° with ramp height 0.5 times of cavity depth. At these 2 configurations, moment about the center of the cavity floor was reduced significantly. These could be attributed to the more steady flow within the cavity as compared to the baseline case. Spatial correlation of velocity in the cavity of ramp angle 30° showed that internal cavity flow was less sensitive to flow changes in the shear layer as compared to the baseline case. In the same cavity, snapshot Proper Orthogonal Decomposition revealed a redistribution of energy content where energetic structures exist only in the shear layer as opposed to energetic structures in both the shear layer and internal cavity for the baseline case. A reduction of pressure drag was also observed as the gentle ramp angle of 30° guides the flow smoothly out of the cavity and reduces trailing edge impingement

  4. Noninvasive calculation of the aortic blood pressure waveform from the flow velocity waveform: a proof of concept.

    Science.gov (United States)

    Vennin, Samuel; Mayer, Alexia; Li, Ye; Fok, Henry; Clapp, Brian; Alastruey, Jordi; Chowienczyk, Phil

    2015-09-01

    Estimation of aortic and left ventricular (LV) pressure usually requires measurements that are difficult to acquire during the imaging required to obtain concurrent LV dimensions essential for determination of LV mechanical properties. We describe a novel method for deriving aortic pressure from the aortic flow velocity. The target pressure waveform is divided into an early systolic upstroke, determined by the water hammer equation, and a diastolic decay equal to that in the peripheral arterial tree, interposed by a late systolic portion described by a second-order polynomial constrained by conditions of continuity and conservation of mean arterial pressure. Pulse wave velocity (PWV, which can be obtained through imaging), mean arterial pressure, diastolic pressure, and diastolic decay are required inputs for the algorithm. The algorithm was tested using 1) pressure data derived theoretically from prespecified flow waveforms and properties of the arterial tree using a single-tube 1-D model of the arterial tree, and 2) experimental data acquired from a pressure/Doppler flow velocity transducer placed in the ascending aorta in 18 patients (mean ± SD: age 63 ± 11 yr, aortic BP 136 ± 23/73 ± 13 mmHg) at the time of cardiac catheterization. For experimental data, PWV was calculated from measured pressures/flows, and mean and diastolic pressures and diastolic decay were taken from measured pressure (i.e., were assumed to be known). Pressure reconstructed from measured flow agreed well with theoretical pressure: mean ± SD root mean square (RMS) error 0.7 ± 0.1 mmHg. Similarly, for experimental data, pressure reconstructed from measured flow agreed well with measured pressure (mean RMS error 2.4 ± 1.0 mmHg). First systolic shoulder and systolic peak pressures were also accurately rendered (mean ± SD difference 1.4 ± 2.0 mmHg for peak systolic pressure). This is the first noninvasive derivation of aortic pressure based on fluid dynamics (flow and wave speed) in the

  5. Propagation of Local Bubble Parameters of Subcooled Boiling Flow in a Pressurized Vertical Annulus Channel

    International Nuclear Information System (INIS)

    Chu, In-Cheol; Lee, Seung Jun; Youn, Young Jung; Park, Jong Kuk; Choi, Hae Seob; Euh, Dong Jin

    2015-01-01

    CMFD (Computation Multi-Fluid Dynamics) tools have been being developed to simulate two-phase flow safety problems in nuclear reactor, including the precise prediction of local bubble parameters in subcooled boiling flow. However, a lot of complicated phenomena are encountered in the subcooled boiling flow such as bubble nucleation and departure, interfacial drag of bubbles, lateral migration of bubbles, bubble coalescence and break-up, and condensation of bubbles, and the constitutive models for these phenomena are not yet complete. As a result, it is a difficult task to predict the radial profile of bubble parameters and its propagation along the flow direction. Several experiments were performed to measure the local bubble parameters for the validation of the CMFD code analysis and improvement of the constitutive models of the subcooled boiling flow, and to enhance the fundamental understanding on the subcooled boiling flow. The information on the propagation of the local flow parameters along the flow direction was not provided because the measurements were conducted at the fixed elevation. In SUBO experiments, the radial profiles of local bubble parameters, liquid velocity and temperature were obtained for steam-water subcooled boiling flow in a vertical annulus. The local flow parameters were measured at six elevations along the flow direction. The pressure was in the range of 0.15 to 0.2 MPa. We have launched an experimental program to investigate quantify the local subcooled boiling flow structure under elevated pressure condition in order to provide high precision experimental data for thorough validation of up-to-date CMFD codes. In the present study, the first set of experimental data on the propagation of the radial profile of the bubble parameters was obtained for the subcooled boiling flow of R-134a in a pressurized vertical annulus channel. An experimental program was launched for an in-depth investigation of a subcooled boiling flow in an elevated

  6. BWR core response to fluctuations in coolant flow and pressure, with implications on noise diagnosis and stability monitoring

    International Nuclear Information System (INIS)

    Blomstrand, J.H.; Andersson, S.A.

    1982-01-01

    Reactor dynamic tests, utilizing sinuosidal oscillations in pressure and recirculation flow, have been conducted in operating BWRs in Sweden and Finland. Test data recorded, as well as recordings of process noise, have been analyzed in terms of dynamic core properties. The results obtained show good qualitative agreement with model predictions of BWR core dynamics. Model studies can often support interpretation of dynamic information obtained from operating plants. Comparisons between model studies, dynamic tests and process noise may also provide improved understanding of test results and noise patterns; in this way it can be demonstrated that some neutron flux noise is caused by noise in coolant flow and steam flow. From reactor test data nd noise recordings, core stability parameters have been evaluated by a number of methods. These have been found to provide essentially the same results. The cores investigated were found to be very stable under normal operating conditions. In special operating points, outside the normal operating range, higher decay ratios may occur. The experience indicates that for BWR cores, operated at decay ratios above quarter damping, the stability parameters may be identified from the oscillatory behavior of the autocorrelation in the time domain of the neutron flux noise

  7. Fluid-flow monitoring using electromagnetic probing

    International Nuclear Information System (INIS)

    Lytle, R.J.; Lager, D.L.; Laine, E.F.; Salisbury, J.D.; Okada, J.T.

    1979-01-01

    High-frequency electromagnetic probing is used to monitor the rate and direction of flow of fluids injected into the ground. This method shows the potential for providing more detailed information than procedures presently used. The experimental technique and the test-of-concept experimental results are discussed. This technique has applications in oil-reservoir engineering and in hydrology studies concerning storage of chemical and nuclear wastes. 11 figures

  8. Development of the test facilities for the measurement of core flow and pressure distribution of SMART reactor

    International Nuclear Information System (INIS)

    Ko, Y.J.; Euh, D.J.; Youn, Y.J.; Chu, I.C.; Kwon, T.S.

    2011-01-01

    A design of SMART reactor has been developed, of which the primary system is composed of four internal circulation pumps, a core of 57 fuel assemblies, eight cassettes of steam generators, flow mixing head assemblies, and other internal structures. Since primary design features are very different from conventional reactors, the characteristics of flow and pressure distribution are expected to be different accordingly. In order to analyze the thermal margin and hydraulic design characteristics of SMART reactor, design quantification tests for flow and pressure distribution with a preservation of flow geometry are necessary. In the present study, the design feature of the test facility in order to investigate flow and pressure distribution, named “SCOP” is described. In order to preserve the flow distribution characteristics, the SCOP is linearly reduced with a scaling ratio of 1/5. The core flow rate of each fuel assembly is measured by a venturi meter attached in the lower part of the core simulator having a similarity of pressure drop for nominally scaled flow conditions. All the 57 core simulators and 8 S/G simulators are precisely calibrated in advance of assembling in test facilities. The major parameters in tests are pressures, differential pressures, and core flow distribution. (author)

  9. Pressure drop and flow distribution characteristics of single and parallel serpentine flow fields for polymer electrolyte membrane fuel cells

    International Nuclear Information System (INIS)

    Baek, Seung Man; Kim, Charn Jung; Jeon, Dong Hyup; Nam, Jin Hyun

    2012-01-01

    This study numerically investigates pressure drop and flow distribution characteristics of serpentine flow fields (SFFs) that are designed for polymer electrolyte membrane fuel cells, which consider the Poiseuille flow with secondary pressure drop in the gas channel (GC) and the Darcy flow in the porous gas diffusion layer (GDL). The numerical results for a conventional SFF agreed well with those obtained via computational fluid dynamics simulations, thus proving the validity of the present flow network model. This model is employed to characterize various single and parallel SFFs, including multi-pass serpentine flow fields (MPSFFs). Findings reveal that under rib convection (convective flow through GDL under an interconnector rib) is an important transport process for conventional SFFs, with its intensity being significantly enhanced as GDL permeability increases. The results also indicate that under rib convection can be significantly improved by employing MPSFFs as the reactant flow field, because of the closely interlaced structure of GC regions that have different path lengths from the inlet. However, reactant flow rate through GCs proportionally decreases as under rib convection intensity increases, suggesting that proper optimization is required between the flow velocity in GCs and the under rib convection intensity in GDLs

  10. On the pathogenesis of bedsores. Skin blood flow cessation by external pressure on the back

    DEFF Research Database (Denmark)

    Larsen, B; Holstein, P; Lassen, N A

    1979-01-01

    This paper is devoted to elucidation of the question: Which external pressure is required to stop skin blood flow at the skin - support interface in humans lying on the back in the supine position? Cessation of blood flow was recorded as cessation of washout of an intracutaneous depot of 131I......-antipyrine mixed with histamine. The external pressure was measured by a small airfilled plastic cushion connected to a mercury manometer. In 11 normal subjects, eight patients with hypertension and seven patients with tetra- or paraplegia the "flow cessation external pressure" (FCEP) was strongly correlated...... to the auscultatory brachial mean blood pressure (p less than or equal to 0.001). The difference mean blood pressure - FCEP was on average 4 mmHg (range (-11) - (+20) mmHg) and there was no significant difference between the three groups studied. Thus external pressure exceeding the actual mean blood pressure...

  11. Numerical Simulation of Borehole Flow in Deep Monitor Wells, Pearl Harbor Aquifer, Oahu, Hawaii

    Science.gov (United States)

    Rotzoll, K.; Oki, D. S.; El-Kadi, A. I.

    2010-12-01

    Salinity profiles collected from uncased deep monitor wells are commonly used to monitor freshwater-lens thickness in coastal aquifers. However, vertical flow in these wells can cause the measured salinity to differ from salinity in the adjacent aquifer. Substantial borehole flow has been observed in uncased wells in the Pearl Harbor aquifer, Oahu, Hawaii. A numerical modeling approach, incorporating aquifer hydraulic characteristics and recharge rates representative of the Pearl Harbor aquifer, was used to evaluate the effects of borehole flow on measured salinity profiles from deep monitor wells. Borehole flow caused by vertical hydraulic gradients associated with the natural regional groundwater-flow system and local groundwater withdrawals was simulated. Model results were used to estimate differences between vertical salinity profiles in deep monitor wells and the adjacent aquifer in areas of downward, horizontal, and upward flow within the regional flow system—for cases with and without nearby pumped wells. Aquifer heterogeneity, represented in the model as layers of contrasting permeability, was incorporated in model scenarios. Results from this study provide insight into the magnitude of the differences between vertical salinity profiles from deep monitor wells and the salinity distributions in the aquifers. These insights are relevant and are critically needed for management and predictive modeling purposes.

  12. Electrostatic discharges and their effect on the validity of registered values in intracranial pressure monitors

    DEFF Research Database (Denmark)

    Andresen, Morten; Thomsen, Ole Cornelius; Juhler, Marianne

    2013-01-01

    Object Intracranial pressure (ICP) monitoring is used extensively in clinical practice, and as such, the accuracy of registered ICP values is paramount. Clinical observations of nonphysiological changes in ICP have called into question the accuracy of registered ICP values. Subsequently, the auth......Object Intracranial pressure (ICP) monitoring is used extensively in clinical practice, and as such, the accuracy of registered ICP values is paramount. Clinical observations of nonphysiological changes in ICP have called into question the accuracy of registered ICP values. Subsequently......, the authors have tried to determine if the ICP monitors from major manufacturers were affected by electrostatic discharges (ESDs), if the changes were permanent or transient in nature, and if the changes were modified by the addition of different electrical appliances normally used in the neurointensive care....... Results Five pressure monitors from 4 manufacturers were evaluated. Three monitors containing electrical circuitry at the tip of the transducer were all affected by ESDs. Clinically significant permanent changes in the reported ICP values for 1 pressure monitor were observed, as well as temporary...

  13. Characterization of Rare Reverse Flow Events in Adverse Pressure Gradient Turbulent Boundary Layers

    Science.gov (United States)

    Kaehler, Christian J.; Bross, Matthew; Fuchs, Thomas

    2017-11-01

    Time-resolved tomographic flow fields measured in the viscous sublayer region of a turbulent boundary layer subjected to an adverse pressure gradient (APG) are examined with the aim to resolve and characterize reverse flow events at Reτ = 5000. The fields were measured using a novel high resolution tomographic particle tracking technique. It is shown that this technique is able to fully resolve mean and time dependent features of the complex three-dimensional flow with high accuracy down to very near-wall distances ( 10 μm). From time resolved Lagrangian particle trajectories, statistical information as well as instantaneous topological features of near-wall flow events are deduced. Similar to the zero pressure gradient case (ZPG), it was found that individual events with reverse flow components still occur relatively rarely under the action of the pressure gradient investigated here. However, reverse flow events comprised of many individual events, are shown to appear in relatively organized groupings in both spanwise and streamise directions. Furthermore, instantaneous measurements of reverse flow events show that these events are associated with the motion of low-momentum streaks in the near-wall region. This work is supported by the Priority Programme SPP 1881 Turbulent Superstructures and the individual project Grant KA1808/8-2 of the Deutsche Forschungsgemeinschaft.

  14. Cardiovascular fluid dynamics. Methods for flow and pressure field analysis from magnetic resonance imaging

    International Nuclear Information System (INIS)

    Ebbers, T.

    2001-01-01

    Cardiovascular blood flow is highly complex and incompletely understood. Blood flow patterns are expected to influence the opening and closing of normal and prosthetic heart valves, the efficiency of cardiac filling and ejection, and the resistance to thrombus formation within the heart. Conventional diagnostic techniques are poorly suited to the study of the three-dimensional (3D) blood flow patterns in the heart chambers and large vessels. Noninvasive methods have also been inadequate in studying intracardiac pressure differences, which are the driving force of flow and are critical in the evaluation of many cardiovascular abnormalities. This thesis focuses on the development of non-invasive methods for analysis of 3D cardiovascular blood flow. Simultaneous study of cardiovascular fluid dynamics allowed knowledge exchange across the two disciplines, facilitating the development process and broadening the applicability of the methods. A time-resolved 3D phase-contrast Magnetic Resonance Imaging (MRI) technique was used to acquire the velocity vector field in a 3D volume encompassing the entire heart or a large vessel. Cardiovascular blood flow patterns were visualized by use of particle traces, which revealed, for instance, vortical flow patterns in the left atrium. By applying the Navier-Stokes equation along a user-defined line in the 3D velocity vector field, the relative pressure could be obtained as an excellent supplement to the flow pattern visualization. Using a delineation of the blood pool, the time-varying 3D relative pressure field in the human left ventricle was obtained from the velocity field by use of the pressure Poisson equation. A delineation of the heart muscle, a task that is almost impossible to perform on 3D MRI either automatically or manually, was also achieved by usage of particle traces. This segmentation allows automatic calculation of the 3D relative pressure field, as well as calculation of well-established parameters such as

  15. Cardiovascular fluid dynamics. Methods for flow and pressure field analysis from magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Ebbers, T

    2001-05-01

    Cardiovascular blood flow is highly complex and incompletely understood. Blood flow patterns are expected to influence the opening and closing of normal and prosthetic heart valves, the efficiency of cardiac filling and ejection, and the resistance to thrombus formation within the heart. Conventional diagnostic techniques are poorly suited to the study of the three-dimensional (3D) blood flow patterns in the heart chambers and large vessels. Noninvasive methods have also been inadequate in studying intracardiac pressure differences, which are the driving force of flow and are critical in the evaluation of many cardiovascular abnormalities. This thesis focuses on the development of non-invasive methods for analysis of 3D cardiovascular blood flow. Simultaneous study of cardiovascular fluid dynamics allowed knowledge exchange across the two disciplines, facilitating the development process and broadening the applicability of the methods. A time-resolved 3D phase-contrast Magnetic Resonance Imaging (MRI) technique was used to acquire the velocity vector field in a 3D volume encompassing the entire heart or a large vessel. Cardiovascular blood flow patterns were visualized by use of particle traces, which revealed, for instance, vortical flow patterns in the left atrium. By applying the Navier-Stokes equation along a user-defined line in the 3D velocity vector field, the relative pressure could be obtained as an excellent supplement to the flow pattern visualization. Using a delineation of the blood pool, the time-varying 3D relative pressure field in the human left ventricle was obtained from the velocity field by use of the pressure Poisson equation. A delineation of the heart muscle, a task that is almost impossible to perform on 3D MRI either automatically or manually, was also achieved by usage of particle traces. This segmentation allows automatic calculation of the 3D relative pressure field, as well as calculation of well-established parameters such as

  16. Development and testing of a transparent membrane biofouling monitor

    KAUST Repository

    Dreszer, C.; Flemming, Hans Curt; Wexler, Adam D.; Zwijnenburg, Arie; Kruithof, Joop C.; Vrouwenvelder, Johannes S.

    2014-01-01

    A modified version of the membrane fouling simulator (MFS) was developed for assessment of (i) hydraulic biofilm resistance, (ii) performance parameters feed-channel pressure drop and transmembrane pressure drop, and (iii) in situ spatial visual and optical observations of the biofilm in the transparent monitor, e.g. using optical coherence tomography. The flow channel height equals the feed spacer thickness enabling operation with and without feed spacer. The effective membrane surface area was enlarged from 80 to 200 cm2 by increasing the monitor width compared to the standard MFS, resulting in larger biomass amounts for analysis. By use of a microfiltration membrane (pore size 0.05 μm) in the monitor salt concentration polarization is avoided, allowing operation at low pressures enabling accurate measurement of the intrinsic hydraulic biofilm resistance. Validation tests on e.g. hydrodynamic behavior, flow field distribution, and reproducibility showed that the small-sized monitor was a representative tool for membranes used in practice under the same operating conditions, such as spiral-wound nanofiltration and reverse osmosis membranes. Monitor studies with and without feed spacer use at a flux of 20 L m-2 h-1 and a cross-flow velocity of 0.1 m s-1 clearly showed the suitability of the monitor to determine hydraulic biofilm resistance and for controlled biofouling studies. © 2013 Balaban Desalination Publications. All rights reserved.

  17. Development and testing of a transparent membrane biofouling monitor

    KAUST Repository

    Dreszer, C.

    2014-01-02

    A modified version of the membrane fouling simulator (MFS) was developed for assessment of (i) hydraulic biofilm resistance, (ii) performance parameters feed-channel pressure drop and transmembrane pressure drop, and (iii) in situ spatial visual and optical observations of the biofilm in the transparent monitor, e.g. using optical coherence tomography. The flow channel height equals the feed spacer thickness enabling operation with and without feed spacer. The effective membrane surface area was enlarged from 80 to 200 cm2 by increasing the monitor width compared to the standard MFS, resulting in larger biomass amounts for analysis. By use of a microfiltration membrane (pore size 0.05 μm) in the monitor salt concentration polarization is avoided, allowing operation at low pressures enabling accurate measurement of the intrinsic hydraulic biofilm resistance. Validation tests on e.g. hydrodynamic behavior, flow field distribution, and reproducibility showed that the small-sized monitor was a representative tool for membranes used in practice under the same operating conditions, such as spiral-wound nanofiltration and reverse osmosis membranes. Monitor studies with and without feed spacer use at a flux of 20 L m-2 h-1 and a cross-flow velocity of 0.1 m s-1 clearly showed the suitability of the monitor to determine hydraulic biofilm resistance and for controlled biofouling studies. © 2013 Balaban Desalination Publications. All rights reserved.

  18. Validation of A&D TM-2430 upper-arm blood pressure monitor for ambulatory blood pressure monitoring in children and adolescents, according to the British Hypertension Society protocol.

    Science.gov (United States)

    Yip, Gabriel Wai-Kwok; So, Hung-Kwan; Li, Albert Martin; Tomlinson, Brian; Wong, Sik-Nin; Sung, Rita Yn-Tz

    2012-04-01

    The A&D TM-2430 ambulatory blood pressure (BP) monitor has been validated in adults but not in a young population. We sought to validate the device monitoring in children and adolescents, according to the British Hypertension Society (BHS) protocol. The A&D TM-2430 is an automated oscillometric upper-arm device for ambulatory BP monitoring. Nine consecutive measurements were taken in 61 children (mean age, 9.8 years; range, 5-15 years) according to the BHS criteria. Overseen by an independent supervisor, measurements were recorded by two observers blinded from each other's readings and from the device readings. The mean difference ± SD between the observers and device measurements was 0.73 ± 1.64 mmHg for systolic blood pressure (SBP) and -1.23 ± 1.65 mmHg for diastolic blood pressure (DBP), respectively, with an interobserver difference of 4 mmHg. The cumulative percentages of differences within 5, 10, and 15 mmHg were 89, 95, and 98% for SBP and 67, 88, and 98% for DBP. The device achieved a grade A rating for SBP and a B grade for DBP. The A&D TM-2430 upper-arm BP monitor has fulfilled the required BHS standards and can be recommended for measuring ambulatory BP in children and adolescent populations.

  19. Intraspinal Pressure Monitoring in a Patient with Spinal Cord Injury Reveals Different Intradural Compartments: Injured Spinal Cord Pressure Evaluation (ISCoPE) Study.

    OpenAIRE

    Phang, I; Papadopoulos, MC

    2015-01-01

    BACKGROUND: We recently described a technique for monitoring intraspinal pressure (ISP) after traumatic spinal cord injury (TSCI). This is analogous to intracranial pressure monitoring after brain injury. We showed that, after severe TSCI, ISP at the injury site is elevated as the swollen cord is compressed against the dura. METHODS: In a patient with complete thoracic TSCI, we sequentially monitored subdural ISP above the injury, at the injury site, and below the injury intraoperatively. Pos...

  20. Pressure Drop Across Woven Screens Under Uniform and Nonuniform Flow Conditions. [flow characteristics of water through Dutch twill and square weave fabrics

    Science.gov (United States)

    Ludewig, M.; Omori, S.; Rao, G. L.

    1974-01-01

    Tests were conducted to determine the experimental pressure drop and velocity data for water flowing through woven screens. The types of materials used are dutch twill and square weave fabrics. Pressure drop measures were made at four locations in a rectangular channel. The data are presented as change in pressure compared with the average entry velocity and the numerical relationship is determined by dividing the volumetric flow rate by the screen area open to flow. The equations of continuity and momentum are presented. A computer program listing an extension of a theoretical model and data from that computer program are included.

  1. Sludge pipe flow pressure drop prediction using composite power ...

    African Journals Online (AJOL)

    2011-09-30

    Sep 30, 2011 ... 3Department of Chemical Engineering, IIT Kanpur, India. Abstract. When predicting pressure gradients for the flow of sludges in pipes, the rheology of the fluid ..... implicit in the stability analysis of Ryan and Johnson (1959).

  2. The calculation of dryout during flow and pressure transients

    International Nuclear Information System (INIS)

    James, P.W.; Whalley, P.B.

    1981-01-01

    The method for predicting dryout in a round tube by means of an annular flow model (Whalley et al 1974) is extended to cover the case where both inlet mass flux and pressure are time-dependent. The qualitative effects of an inlet pressure transient are assessed by performing a 'numerical experiment' and it is found that the predictions of the model represent reasonable physical trends. The relative merits of wo numerical solution schemes are also discussed

  3. Non-Newtonian Flow-Induced Deformation From Pressurized Cavities in Absorbing Porous Tissues

    Science.gov (United States)

    Ahmed, Aftab; Siddique, Javed

    2017-11-01

    We investigate the behavior of a spherical cavity in a soft biological tissue modeled as a deformable porous material during an injection of non-Newtonian fluid that follows a power law model. Fluid flows into the neighboring tissue due to high cavity pressure where it is absorbed by capillaries and lymphatics at a rate proportional to the local pressure. Power law fluid pressure and displacement of solid in the tissue are computed as function of radial distance and time. Numerical solutions indicate that shear thickening fluids exhibit less fluid pressure and induce small solid deformation as compared to shear thinning fluids. The absorption in the biological tissue increases as a consequence of flow induced deformation for power law fluids. In most cases non-Newtonian results are compared with viscous fluid case to magnify the differences.

  4. Implementation of the Fissile Mass Flow Monitor Source Verification and Confirmation

    Energy Technology Data Exchange (ETDEWEB)

    Uckan, Taner [ORNL; March-Leuba, Jose A [ORNL; Powell, Danny H [ORNL; Nelson, Dennis [Sandia National Laboratories (SNL); Radev, Radoslav [Lawrence Livermore National Laboratory (LLNL)

    2007-12-01

    This report presents the verification procedure for neutron sources installed in U.S. Department of Energy equipment used to measure fissile material flow. The Fissile Mass Flow Monitor (FMFM) equipment determines the {sup 235}U fissile mass flow of UF{sub 6} gas streams by using {sup 252}Cf neutron sources for fission activation of the UF{sub 6} gas and by measuring the fission products in the flow. The {sup 252}Cf sources in each FMFM are typically replaced every 2 to 3 years due to their relatively short half-life ({approx} 2.65 years). During installation of the new FMFM sources, the source identity and neutronic characteristics provided by the manufacturer are verified with the following equipment: (1) a remote-control video television (RCTV) camera monitoring system is used to confirm the source identity, and (2) a neutron detection system (NDS) is used for source-strength confirmation. Use of the RCTV and NDS permits remote monitoring of the source replacement process and eliminates unnecessary radiation exposure. The RCTV, NDS, and the confirmation process are described in detail in this report.

  5. Implementation of the Fissile Mass Flow Monitor Source Verification and Confirmation

    International Nuclear Information System (INIS)

    Uckan, Taner; March-Leuba, Jose A.; Powell, Danny H.; Nelson, Dennis; Radev, Radoslav

    2007-01-01

    This report presents the verification procedure for neutron sources installed in U.S. Department of Energy equipment used to measure fissile material flow. The Fissile Mass Flow Monitor (FMFM) equipment determines the 235 U fissile mass flow of UF 6 gas streams by using 252 Cf neutron sources for fission activation of the UF 6 gas and by measuring the fission products in the flow. The 252 Cf sources in each FMFM are typically replaced every 2 to 3 years due to their relatively short half-life (∼ 2.65 years). During installation of the new FMFM sources, the source identity and neutronic characteristics provided by the manufacturer are verified with the following equipment: (1) a remote-control video television (RCTV) camera monitoring system is used to confirm the source identity, and (2) a neutron detection system (NDS) is used for source-strength confirmation. Use of the RCTV and NDS permits remote monitoring of the source replacement process and eliminates unnecessary radiation exposure. The RCTV, NDS, and the confirmation process are described in detail in this report.

  6. Continuous flow left ventricular assist devices: shared care goals of monitoring and treating patients.

    Science.gov (United States)

    Estep, Jerry D; Trachtenberg, Barry H; Loza, Laurie P; Bruckner, Brian A

    2015-01-01

    Continuous-flow left ventricular assist devices (CF-LVADs) have been clinically adopted as a long-term standard of care therapy option for patients with end-stage heart failure. For many patients, shared care between the care providers at the implanting center and care providers in the community in which the patient resides is a clinical necessity. The aims of this review are to (1) provide a rationale for the outpatient follow-up exam and surveillance testing used at our center to monitor patients supported by the HeartMate II(®) CF-LVAD (Thoratec Corporation, Pleasanton, CA) and (2) provide the protocol/algorithms we use for blood pressure, driveline exit site, LVAD alarm history, surveillance blood work, and echocardiography monitoring in this patient population. In addition, we define our partnership outpatient follow-up protocol and the "shared care" specific responsibilities we use with referring health care providers to best manage many of our patients.

  7. Investigation of technology for the monitoring of UF6 mass flow in UF6 streams diluted with H2

    International Nuclear Information System (INIS)

    Baker, O.J.; Cooley, J.N.; Hewgley, W.A.; Moran, B.W.; Swindle, D.W. Jr.

    1986-12-01

    The applicability, availability, and effectiveness of gas flow meters are assessed as a means for verifying the mass flows of pure UF 6 streams diluted with a carrier gas. The initial survey identified the orifice, pitot tube, thermal, vortex shedding, and vortex precession (swirl) meters as promising for the intended use. Subsequent assessments of these flow meters revealed that two - the orifice meter and the pitot tube meter - are the best choices for the proposed applications: the first is recommended for low velocity gas, small diameter piping; the latter, for high velocity gas, large diameter piping. Final selection of the gas flow meters should be based on test loop evaluations in which the proposed meters are subjected to gas flows, temperatures, and pressures representative of those expected in service. Known instruments are evaluated that may be applicable to the measurement of uranium or UF 6 concentration in a UF 6 - H 2 process stream at an aerodynamic enrichment plant. Of the six procedures evaluated, four have been used for process monitoring in a UF 6 environment: gas mass spectrometry, infrared-ultraviolet-visible spectrophotometry, gas chromatography, and acoustic gas analysis. The remaining two procedures, laser fluorimetry and atomic absorption spectroscopy, would require significant development work before they could be used for process monitoring. Infrared-ultravioloet-visible spectrophotometry is judged to be the best procedure currently available to perform the required measurement

  8. Calculation of pressure gradients from MR velocity data in a laminar flow model

    International Nuclear Information System (INIS)

    Adler, R.S.; Chenevert, T.L.; Fowlkes, J.B.; Pipe, J.G.; Rubin, J.M.

    1990-01-01

    This paper reports on the ability of current imaging modalities to provide velocity-distribution data that offers the possibility of noninvasive pressure-gradient determination from an appropriate rheologic model of flow. A simple laminar flow model is considered at low Reynolds number, RE calc = 0.59 + (1.13 x (dp/dz) meas ), R 2 = .994, in units of dyne/cm 2 /cm for the range of flows considered. The authors' results indicate the potential usefulness of noninvasive pressure-gradient determinations from quantitative analysis of imaging-derived velocity data

  9. A New Way to Calculate Flow Pressure for Low Permeability Oil Well with Partially Penetrating Fracture

    Directory of Open Access Journals (Sweden)

    Xiong Ping

    2018-01-01

    Full Text Available In order to improve the validity of the previous models on calculating flow pressure for oil well with partially perforating fracture, a new physical model that obeys the actual heterogeneous reservoir characteristics was built. Different conditions, including reservoir with impermeable top and bottom borders or the reservoir top which has constant pressure, were considered. Through dimensionless transformation, Laplace transformation, Fourier cosine transformation, separation of variables, and other mathematical methods, the analytical solution of Laplace domain was obtained. By using Stephenson numerical methods, the numerical solution pressure in a real domain was obtained. The results of this method agree with the numerical simulations, suggesting that this new method is reliable. The following sensitivity analysis showed that the pressure dynamic linear flow curve can be divided into four flow streams of early linear flow, midradial flow, advanced spherical flow, and border controlling flow. Fracture length controls the early linear flow. Permeability anisotropy significantly affects the midradial flow. The degree of penetration and fracture orientation dominantly affect the late spherical flow. The boundary conditions and reservoir boundary width mainly affect the border controlling flow. The method can be used to determine the optimal degree of opening shot, vertical permeability, and other useful parameters, providing theoretical guidance for reservoir engineering analysis.

  10. A feasability study of color flow doppler vectorization for automated blood flow monitoring.

    Science.gov (United States)

    Schorer, R; Badoual, A; Bastide, B; Vandebrouck, A; Licker, M; Sage, D

    2017-12-01

    An ongoing issue in vascular medicine is the measure of the blood flow. Catheterization remains the gold standard measurement method, although non-invasive techniques are an area of intense research. We hereby present a computational method for real-time measurement of the blood flow from color flow Doppler data, with a focus on simplicity and monitoring instead of diagnostics. We then analyze the performance of a proof-of-principle software implementation. We imagined a geometrical model geared towards blood flow computation from a color flow Doppler signal, and we developed a software implementation requiring only a standard diagnostic ultrasound device. Detection performance was evaluated by computing flow and its determinants (flow speed, vessel area, and ultrasound beam angle of incidence) on purposely designed synthetic and phantom-based arterial flow simulations. Flow was appropriately detected in all cases. Errors on synthetic images ranged from nonexistent to substantial depending on experimental conditions. Mean errors on measurements from our phantom flow simulation ranged from 1.2 to 40.2% for angle estimation, and from 3.2 to 25.3% for real-time flow estimation. This study is a proof of concept showing that accurate measurement can be done from automated color flow Doppler signal extraction, providing the industry the opportunity for further optimization using raw ultrasound data.

  11. Pressure loss of the annular air-liquid flow in vertical tufes

    Energy Technology Data Exchange (ETDEWEB)

    Schmal, M [Rio de Janeiro Univ. (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia; Cantalino, A [Rio de Janeiro Univ. (Brazil). Dept. de Engenharia Quimica

    1976-01-01

    In this work the pressure loss of the annular air-liquid flow in vertical tubes has been determined. Correlations are presented for the frictional pressure drop. The dimensional analysis and the following fluid systems were used for this determination: air-water, air-alcohol solutions and air-water and surfactants.

  12. Flow Instabilities and Main Steam Line Vibrations in a Pressurized Water Reactor

    International Nuclear Information System (INIS)

    Henriksson, Mats; Westin, Johan; Granhall, Tord; Andersson, Lars; Bjerke, Lars-Erik

    2002-01-01

    Severe vibrational problems occurred in the main steam system of a PWR nuclear power plant, about 18 months after a steam generator replacement had been carried out. The magnitude of the vibrations reached levels at which the operators had to reduce power in order to stay within the operating limits imposed by the nuclear inspectorate. To solve the problem the following analyses methods were employed: - Testing the influence on vibration level from different modes of plant operation; - Analyses of plant measurement data; - Calculations of: hydraulic behaviour of the system, structural dynamic behaviour of the system, flow at the steam generator outlet. Scale model testing of the steam generator outlet region. Hydraulic flow disturbances in the main steam system were measured using pressure and strain gauges, which made it possible to track individual pressure pulses propagating through the main steam system. Analyses showed that the pressure pulses causing the vibration originated from the vicinity of the steam generator outlet. By using computer codes for network fluid flow analyses the pressure pulses found in the measurement traces could be generated in calculations. Careful studies of the flow at the steam generator outlet region, using model testing in a 1:3 scale model as well as transient 3D CFD calculations, gave clear indications that flow separation occurred at the steam generator outlet nozzle and at the first bend. Finally, by substituting the outlet nozzle for a different design with a multi-port nozzle, the steam line vibration problem has been solved. (authors)

  13. Influence of isoflurane on the diastolic pressure-flow relationship and critical occlusion pressure during arterial CABG surgery: a randomized controlled trial.

    Science.gov (United States)

    Hinz, José; Mansur, Ashham; Hanekop, Gerd G; Weyland, Andreas; Popov, Aron F; Schmitto, Jan D; Grüne, Frank F G; Bauer, Martin; Kazmaier, Stephan

    2016-01-01

    The effects of isoflurane on the determinants of blood flow during Coronary Artery Bypass Graft (CABG) surgery are not completely understood. This study characterized the influence of isoflurane on the diastolic Pressure-Flow (P-F) relationship and Critical Occlusion Pressure (COP) during CABG surgery. Twenty patients undergoing CABG surgery were studied. Patients were assigned to an isoflurane or control group. Hemodynamic and flow measurements during CABG surgery were performed twice (15 minutes after the discontinuation of extracorporeal circulation (T15) and again 15 minutes later (T30)). The zero flow pressure intercept (a measure of COP) was extrapolated from a linear regression analysis of the instantaneous diastolic P-F relationship. In the isoflurane group, the application of isoflurane significantly increased the slope of the diastolic P-F relationship by 215% indicating a mean reduction of Coronary Vascular Resistance (CVR) by 46%. Simultaneously, the Mean Diastolic Aortic Pressure (MDAP) decreased by 19% mainly due to a decrease in the systemic vascular resistance index by 21%. The COP, cardiac index, heart rate, Left Ventricular End-Diastolic Pressure (LVEDP) and Coronary Sinus Pressure (CSP) did not change significantly. In the control group, the parameters remained unchanged. In both groups, COP significantly exceeded the CSP and LVEDP at both time points. We conclude that short-term application of isoflurane at a sedative concentration markedly increases the slope of the instantaneous diastolic P-F relationship during CABG surgery implying a distinct decrease with CVR in patients undergoing CABG surgery.

  14. A blended pressure/density based method for the computation of incompressible and compressible flows

    International Nuclear Information System (INIS)

    Rossow, C.-C.

    2003-01-01

    An alternative method to low speed preconditioning for the computation of nearly incompressible flows with compressible methods is developed. For this approach the leading terms of the flux difference splitting (FDS) approximate Riemann solver are analyzed in the incompressible limit. In combination with the requirement of the velocity field to be divergence-free, an elliptic equation to solve for a pressure correction to enforce the divergence-free velocity field on the discrete level is derived. The pressure correction equation established is shown to be equivalent to classical methods for incompressible flows. In order to allow the computation of flows at all speeds, a blending technique for the transition from the incompressible, pressure based formulation to the compressible, density based formulation is established. It is found necessary to use preconditioning with this blending technique to account for a remaining 'compressible' contribution in the incompressible limit, and a suitable matrix directly applicable to conservative residuals is derived. Thus, a coherent framework is established to cover the discretization of both incompressible and compressible flows. Compared with standard preconditioning techniques, the blended pressure/density based approach showed improved robustness for high lift flows close to separation

  15. Unsteady Flow Simulation of a Sweeping Jet Actuator Using a Lattice-Boltzmann Method

    Science.gov (United States)

    Duda, B.; Wessels, M.; Fares, E.; Vatsa, V.

    2016-01-01

    Active flow control technology is increasingly used in aerospace applications to control flow separation and to improve aerodynamic performance. In this paper, PowerFLOW is used to simulate the flow through a sweeping jet actuator at two different pressure ratios. The lower pressure ratio leads to a high subsonic flow, whereas the high pressure ratio produces a choked flow condition. Comparison of numerical results with experimental data is shown, which includes qualitatively good agreement of pressure histories and spectra. PIV measurements are also available but the simulation overestimates mean and fluctuation quantities outside the actuator. If supply pressure is matched at one point inside the mixing chamber a good qualitative agreement is achieved at all other monitor points.

  16. Development of a pressure based vortex-shedding meter: measuring unsteady mass-flow in variable density gases

    International Nuclear Information System (INIS)

    Ford, C L; Winroth, M; Alfredsson, P H

    2016-01-01

    An entirely pressure-based vortex-shedding meter has been designed for use in practical time-dependent flows. The meter is capable of measuring mass-flow rate in variable density gases in spite of the fact that fluid temperature is not directly measured. Unlike other vortex meters, a pressure based meter is incredibly robust and may be used in industrial type flows; an environment wholly unsuitable for hot-wires for example. The meter has been tested in a number of static and dynamic flow cases, across a range of mass-flow rates and pressures. The accuracy of the meter is typically better than about 3% in a static flow and resolves the fluctuating mass-flow with an accuracy that is better than or equivalent to a hot-wire method. (paper)

  17. Blow-out limits of nonpremixed turbulent jet flames in a cross flow at atmospheric and sub-atmospheric pressures

    KAUST Repository

    Wang, Qiang

    2015-07-22

    The blow-out limits of nonpremixed turbulent jet flames in cross flows were studied, especially concerning the effect of ambient pressure, by conducting experiments at atmospheric and sub-atmospheric pressures. The combined effects of air flow and pressure were investigated by a series of experiments conducted in an especially built wind tunnel in Lhasa, a city on the Tibetan plateau where the altitude is 3650 m and the atmospheric pressure condition is naturally low (64 kPa). These results were compared with results obtained from a wind tunnel at standard atmospheric pressure (100 kPa) in Hefei city (altitude 50 m). The size of the fuel nozzles used in the experiments ranged from 3 to 8 mm in diameter and propane was used as the fuel. It was found that the blow-out limit of the air speed of the cross flow first increased (“cross flow dominant” regime) and then decreased (“fuel jet dominant” regime) as the fuel jet velocity increased in both pressures; however, the blow-out limit of the air speed of the cross flow was much lower at sub-atmospheric pressure than that at standard atmospheric pressure whereas the domain of the blow-out limit curve (in a plot of the air speed of the cross flow versus the fuel jet velocity) shrank as the pressure decreased. A theoretical model was developed to characterize the blow-out limit of nonpremixed jet flames in a cross flow based on a Damköhler number, defined as the ratio between the mixing time and the characteristic reaction time. A satisfactory correlation was obtained at relative strong cross flow conditions (“cross flow dominant” regime) that included the effects of the air speed of the cross flow, fuel jet velocity, nozzle diameter and pressure.

  18. Non-Invasive Ultrasonic Diagnosing and Monitoring of Intracranial Pressure/Volume

    Science.gov (United States)

    2001-10-01

    Libraria, Padoue (Italia) 53 37. Guinduiz G, Viernstein LW (1979). Intracranial pressure in the normal monkey while awake and asleep. J Neurosurg 51, 206...cerebral microcirculation of awake rabbits. Heart Circ Physiol 23, H67-H71 46. Hyndman BW, Kitney RI, Sayers BM (1971). Spontaneous rhythms in...intracranial pressure monitoring. Exclusion criteria: patients with wounds, scars or a craniotomy overlying the optimal window for transintracranial

  19. Enhancement of Arterial Pressure Pulsatility by Controlling Continuous-Flow Left Ventricular Assist Device Flow Rate in Mock Circulatory System.

    Science.gov (United States)

    Bozkurt, Selim; van de Vosse, Frans N; Rutten, Marcel C M

    Continuous-flow left ventricular assist devices (CF-LVADs) generally operate at a constant speed, which reduces pulsatility in the arteries and may lead to complications such as functional changes in the vascular system, gastrointestinal bleeding, or both. The purpose of this study is to increase the arterial pulse pressure and pulsatility by controlling the CF-LVAD flow rate. A MicroMed DeBakey pump was used as the CF-LVAD. A model simulating the flow rate through the aortic valve was used as a reference model to drive the pump. A mock circulation containing two synchronized servomotor-operated piston pumps acting as left and right ventricles was used as a circulatory system. Proportional-integral control was used as the control method. First, the CF-LVAD was operated at a constant speed. With pulsatile-speed CF-LVAD assistance, the pump was driven such that the same mean pump output was generated. Continuous and pulsatile-speed CF-LVAD assistance provided the same mean arterial pressure and flow rate, while the index of pulsatility increased significantly for both arterial pressure and pump flow rate signals under pulsatile speed pump support. This study shows the possibility of improving the pulsatility of CF-LVAD support by regulating pump speed over a cardiac cycle without reducing the overall level of support.

  20. Reaction of blood pressure and mesenteric blood flow to infusion of biogenic amines in normal and supralethally x-irradiated rats

    International Nuclear Information System (INIS)

    Timmermans, R.; Gerber, G.B.

    1980-01-01

    The responss of blood pressure and mesenteric blood flow were recorded during infusion of biogenic amines (noradrenaline, dopamine, serotonin, acetylcholine, and histamine) to control and x-irradiated rats (first and third days after 2 kR x irradiation). Responses to different doses of the amines were evaluated, and the results obtained correspond to those seen in other species (e.g., an increase in pressure and a decrease in flow after dopamine, an increase in pressure and a decrease in flow after serotonin, a decrease in pressure and flow after acetylcholine, and a decrease in flow after serotonin, a decrease in pressure and flow after acetylcholine, and a decrease in pressure and an increase in flow after histamine). Irradiated animals are more responsive to pressure-raising agents, in particular to noradrenaline. They also have an altered dose-pressure response curve for dopamine

  1. Monitoring individual traffic flows within the ATLAS TDAQ network

    CERN Document Server

    Sjoen, R; Ciobotaru, M; Batraneanu, S M; Leahu, L; Martin, B; Al-Shabibi, A

    2010-01-01

    The ATLAS data acquisition system consists of four different networks interconnecting up to 2000 processors using up to 200 edge switches and five multi-blade chassis devices. The architecture of the system has been described in [1] and its operational model in [2]. Classical, SNMP-based, network monitoring provides statistics on aggregate traffic, but for performance monitoring and troubleshooting purposes there was an imperative need to identify and quantify single traffic flows. sFlow [3] is an industry standard based on statistical sampling which attempts to provide a solution to this. Due to the size of the ATLAS network, the collection and analysis of the sFlow data from all devices generates a data handling problem of its own. This paper describes how this problem is addressed by making it possible to collect and store data either centrally or distributed according to need. The methods used to present the results in a relevant fashion for system analysts are discussed and we explore the possibilities a...

  2. Development of Remote Monitoring and a Control System Based on PLC and WebAccess for Learning Mechatronics

    Directory of Open Access Journals (Sweden)

    Wen-Jye Shyr

    2013-02-01

    Full Text Available This study develops a novel method for learning mechatronics using remote monitoring and control, based on a programmable logic controller (PLC and WebAccess. A mechatronics module, a Web-CAM and a PLC were integrated with WebAccess software to organize a remote laboratory. The proposed system enables users to access the Internet for remote monitoring and control of the mechatronics module via a web browser, thereby enhancing work flexibility by enabling personnel to control mechatronics equipment from a remote location. Mechatronics control and long-distance monitoring were realized by establishing communication between the PLC and WebAccess. Analytical results indicate that the proposed system is feasible. The suitability of this system is demonstrated in the department of industrial education and technology at National Changhua University of Education, Taiwan. Preliminary evaluation of the system was encouraging and has shown that it has achieved success in helping students understand concepts and master remote monitoring and control techniques.

  3. An atmospheric pressure high-temperature laminar flow reactor for investigation of combustion and related gas phase reaction systems.

    Science.gov (United States)

    Oßwald, Patrick; Köhler, Markus

    2015-10-01

    A new high-temperature flow reactor experiment utilizing the powerful molecular beam mass spectrometry (MBMS) technique for detailed observation of gas phase kinetics in reacting flows is presented. The reactor design provides a consequent extension of the experimental portfolio of validation experiments for combustion reaction kinetics. Temperatures up to 1800 K are applicable by three individually controlled temperature zones with this atmospheric pressure flow reactor. Detailed speciation data are obtained using the sensitive MBMS technique, providing in situ access to almost all chemical species involved in the combustion process, including highly reactive species such as radicals. Strategies for quantifying the experimental data are presented alongside a careful analysis of the characterization of the experimental boundary conditions to enable precise numeric reproduction of the experimental results. The general capabilities of this new analytical tool for the investigation of reacting flows are demonstrated for a selected range of conditions, fuels, and applications. A detailed dataset for the well-known gaseous fuels, methane and ethylene, is provided and used to verify the experimental approach. Furthermore, application for liquid fuels and fuel components important for technical combustors like gas turbines and engines is demonstrated. Besides the detailed investigation of novel fuels and fuel components, the wide range of operation conditions gives access to extended combustion topics, such as super rich conditions at high temperature important for gasification processes, or the peroxy chemistry governing the low temperature oxidation regime. These demonstrations are accompanied by a first kinetic modeling approach, examining the opportunities for model validation purposes.

  4. An atmospheric pressure high-temperature laminar flow reactor for investigation of combustion and related gas phase reaction systems

    Energy Technology Data Exchange (ETDEWEB)

    Oßwald, Patrick; Köhler, Markus [Institute of Combustion Technology, German Aerospace Center (DLR), Pfaffenwaldring 38-40, D-70569 Stuttgart (Germany)

    2015-10-15

    A new high-temperature flow reactor experiment utilizing the powerful molecular beam mass spectrometry (MBMS) technique for detailed observation of gas phase kinetics in reacting flows is presented. The reactor design provides a consequent extension of the experimental portfolio of validation experiments for combustion reaction kinetics. Temperatures up to 1800 K are applicable by three individually controlled temperature zones with this atmospheric pressure flow reactor. Detailed speciation data are obtained using the sensitive MBMS technique, providing in situ access to almost all chemical species involved in the combustion process, including highly reactive species such as radicals. Strategies for quantifying the experimental data are presented alongside a careful analysis of the characterization of the experimental boundary conditions to enable precise numeric reproduction of the experimental results. The general capabilities of this new analytical tool for the investigation of reacting flows are demonstrated for a selected range of conditions, fuels, and applications. A detailed dataset for the well-known gaseous fuels, methane and ethylene, is provided and used to verify the experimental approach. Furthermore, application for liquid fuels and fuel components important for technical combustors like gas turbines and engines is demonstrated. Besides the detailed investigation of novel fuels and fuel components, the wide range of operation conditions gives access to extended combustion topics, such as super rich conditions at high temperature important for gasification processes, or the peroxy chemistry governing the low temperature oxidation regime. These demonstrations are accompanied by a first kinetic modeling approach, examining the opportunities for model validation purposes.

  5. Investigation on heat transfer characteristics and flow performance of Methane at supercritical pressures

    Science.gov (United States)

    Xian, Hong Wei; Oumer, A. N.; Basrawi, F.; Mamat, Rizalman; Abdullah, A. A.

    2018-04-01

    The aim of this study is to investigate the heat transfer and flow characteristic of cryogenic methane in regenerative cooling system at supercritical pressures. The thermo-physical properties of supercritical methane were obtained from the National institute of Standards and Technology (NIST) webbook. The numerical model was developed based on the assumptions of steady, turbulent and Newtonian flow. For mesh independence test and model validation, the simulation results were compared with published experimental results. The effect of four different performance parameter ranges namely inlet pressure (5 to 8 MPa), inlet temperature (120 to 150 K), heat flux (2 to 5 MW/m2) and mass flux (7000 to 15000 kg/m2s) on heat transfer and flow performances were investigated. It was found that the simulation results showed good agreement with experimental data with maximum deviation of 10 % which indicates the validity of the developed model. At low inlet temperature, the change of specific heat capacity at near-wall region along the tube length was not significant while the pressure drop registered was high. However, significant variation was observed for the case of higher inlet temperature. It was also observed that the heat transfer performance and pressure drop penalty increased when the mass flux was increased. Regarding the effect of inlet pressure, the heat transfer performance and pressure drop results decreased when the inlet pressure is increased.

  6. Bernoulli's Principle Applied to Brain Fluids: Intracranial Pressure Does Not Drive Cerebral Perfusion or CSF Flow.

    Science.gov (United States)

    Schmidt, Eric; Ros, Maxime; Moyse, Emmanuel; Lorthois, Sylvie; Swider, Pascal

    2016-01-01

    In line with the first law of thermodynamics, Bernoulli's principle states that the total energy in a fluid is the same at all points. We applied Bernoulli's principle to understand the relationship between intracranial pressure (ICP) and intracranial fluids. We analyzed simple fluid physics along a tube to describe the interplay between pressure and velocity. Bernoulli's equation demonstrates that a fluid does not flow along a gradient of pressure or velocity; a fluid flows along a gradient of energy from a high-energy region to a low-energy region. A fluid can even flow against a pressure gradient or a velocity gradient. Pressure and velocity represent part of the total energy. Cerebral blood perfusion is not driven by pressure but by energy: the blood flows from high-energy to lower-energy regions. Hydrocephalus is related to increased cerebrospinal fluid (CSF) resistance (i.e., energy transfer) at various points. Identification of the energy transfer within the CSF circuit is important in understanding and treating CSF-related disorders. Bernoulli's principle is not an abstract concept far from clinical practice. We should be aware that pressure is easy to measure, but it does not induce resumption of fluid flow. Even at the bedside, energy is the key to understanding ICP and fluid dynamics.

  7. Data on a single oral dose of camu camu (Myrciaria dubia pericarp extract on flow-mediated vasodilation and blood pressure in young adult humans

    Directory of Open Access Journals (Sweden)

    Tadayoshi Miyashita

    2018-02-01

    Full Text Available This data article describes the flow-mediated vasodilation (FMD responses, represented by changes in arterial diameter, and blood pressure changes in young adults after a single oral dose of camu camu (Myrciaria dubia pericarp extract or placebo (cross-over design. Ten healthy men and 10 healthy women participated in this study. Ultrasonic diagnostic equipment was used to monitor arterial diameter changes, indicative of FMD, for 110 s after the administration of the camu camu extract or placebo. In addition, the systolic and diastolic blood pressure values were recorded.

  8. Data on a single oral dose of camu camu (Myrciaria dubia) pericarp extract on flow-mediated vasodilation and blood pressure in young adult humans.

    Science.gov (United States)

    Miyashita, Tadayoshi; Koizumi, Ryosuke; Myoda, Takao; Sagane, Yoshimasa; Niwa, Koichi; Watanabe, Toshihiro; Minami, Kazuhiro

    2018-02-01

    This data article describes the flow-mediated vasodilation (FMD) responses, represented by changes in arterial diameter, and blood pressure changes in young adults after a single oral dose of camu camu ( Myrciaria dubia ) pericarp extract or placebo (cross-over design). Ten healthy men and 10 healthy women participated in this study. Ultrasonic diagnostic equipment was used to monitor arterial diameter changes, indicative of FMD, for 110 s after the administration of the camu camu extract or placebo. In addition, the systolic and diastolic blood pressure values were recorded.

  9. Validation of the Andon KD-5965 upper-arm blood pressure monitor for home blood pressure monitoring according to the European Society of Hypertension International Protocol revision 2010.

    Science.gov (United States)

    Huang, Jinhua; Li, Zhijie; Li, Guimei; Liu, Zhaoying

    2015-10-01

    This study aimed to evaluate the accuracy of the Andon KD-5965 upper-arm blood pressure monitor according to the European Society of Hypertension International Protocol revision 2010. Systolic and diastolic blood pressures were sequentially measured in 33 adults, with 20 women using a mercury sphygmomanometer (two observers) and the Andon KD-5965 device (one supervisor). A total of 99 pairs of comparisons were obtained from 33 participants for judgments in two parts with three grading phases. The device achieved the targets in part 1 of the validation study. The number of absolute differences between the device and observers within 5, 10, and 15 mmHg was 70/99, 91/99, and 98/99, respectively, for systolic blood pressure and 81/99, 99/99, and 99/99, respectively, for diastolic blood pressure. The device also fulfilled the criteria in part 2 of the validation study. Twenty-five and 29 participants, for systolic and diastolic blood pressure, respectively, had at least two of the three device-observers differences within 5 mmHg (required≥24). Two and one participants for systolic and diastolic blood pressure, respectively, had all three device-observers comparisons greater than 5 mmHg. According to the validation results, with better performance for diastolic blood pressure than that for systolic blood pressure, the Andon automated oscillometric upper-arm blood pressure monitor KD-5965 fulfilled the requirements of the European Society of Hypertension International Protocol revision 2010, and hence can be recommended for blood pressure measurement in adults.

  10. Development of instrumentation systems for severe accidents. 4. New accident tolerant in-containment pressure transducer for containment pressure monitoring system

    International Nuclear Information System (INIS)

    Oba, Masato; Teruya, Kuniyuki; Yoshitsugu, Makoto; Ikeuchi, Takeshi

    2015-01-01

    The accident at Tokyo Electric Power Company's Fukushima Dai-ichi Nuclear Power Plant (TF-1 accident) caused severe situations and resulted in a difficulty in measuring important parameters for monitoring plant conditions. Therefore, we have studied the TF-1 accident to select the important parameters that should be monitored at the severe accident and are developing the Severe Accident Instrumentations and Monitoring Systems that could measure the parameters in severe accident conditions. Mitsubishi Heavy Industries, LTD (MHI) developed a new accident tolerant containment pressure monitoring system and demonstrated that the monitoring system could endure extremely harsh environmental conditions that envelop severe accident environmental conditions inside a containment such as maximum operating temperature of up to 300degC and total integrated dose (TID) of 1 MGy gamma. The new containment pressure monitoring system comprises of a strain gage type pressure transducer and a mineral insulated (MI) cable with ceramic connectors, which are located in the containment, and a strain measuring amplifier located outside the containment. Less thermal and radiation degradation is achieved because of minimizing use of organic materials for in-containment equipment such as the transducer and connectors. Several tests were performed to demonstrate the performance and capability of the in-containment equipment under severe accident environmental conditions and the major steps in this testing were run in the following test sequences: (1) the baseline functional tests (e.g., repeatability, non-linearity, hysteresis, and so on) under normal conditions, (2) accident radiation testing, (3) seismic testing, and (4) steam/temperature test exposed to simulated severe accident environmental conditions. The test results demonstrate that the new pressure transducer can endure the simulated severe accident conditions. (author)

  11. Flow-regulated versus differential pressure-regulated shunt valves for adult patients with normal pressure hydrocephalus

    DEFF Research Database (Denmark)

    Ziebell, Morten; Wetterslev, Jørn; Tisell, Magnus

    2013-01-01

    Since 1965 many ventriculo-peritoneal shunt systems have been inserted worldwide to treat hydrocephalus. The most frequent indication in adults is normal pressure hydrocephalus (NPH), a condition that can be difficult to diagnose precisely. Surgical intervention with flow-regulated and differential...

  12. The influence of preferential flow on pressure propagation and landslide triggering of the Rocca Pitigliana landslide

    Science.gov (United States)

    Shao, Wei; Bogaard, Thom; Bakker, Mark; Berti, Matteo

    2016-12-01

    The fast pore water pressure response to rain events is an important triggering factor for slope instability. The fast pressure response may be caused by preferential flow that bypasses the soil matrix. Currently, most of the hydro-mechanical models simulate pore water pressure using a single-permeability model, which cannot quantify the effects of preferential flow on pressure propagation and landslide triggering. Previous studies showed that a model based on the linear-diffusion equation can simulate the fast pressure propagation in near-saturated landslides such as the Rocca Pitigliana landslide. In such a model, the diffusion coefficient depends on the degree of saturation, which makes it difficult to use the model for predictions. In this study, the influence of preferential flow on pressure propagation and slope stability is investigated with a 1D dual-permeability model coupled with an infinite-slope stability approach. The dual-permeability model uses two modified Darcy-Richards equations to simultaneously simulate the matrix flow and preferential flow in hillslopes. The simulated pressure head is used in an infinite-slope stability analysis to identify the influence of preferential flow on the fast pressure response and landslide triggering. The dual-permeability model simulates the height and arrival of the pressure peak reasonably well. Performance of the dual-permeability model is as good as or better than the linear-diffusion model even though the dual-permeability model is calibrated for two single pulse rain events only, while the linear-diffusion model is calibrated for each rain event separately. In conclusion, the 1D dual-permeability model is a promising tool for landslides under similar conditions.

  13. Use of a pressure sensing sheath: comparison with standard means of blood pressure monitoring in catheterization procedures.

    Science.gov (United States)

    Purdy, Phillip D; South, Charles; Klucznik, Richard P; Liu, Kenneth C; Novakovic, Robin L; Puri, Ajit S; Pride, G Lee; Aagaard-Kienitz, Beverly; Ray, Abishek; Elliott, Alan C

    2017-08-01

    Monitoring of blood pressure (BP) during procedures is variable, depending on multiple factors. Common methods include sphygmomanometer (BP cuff), separate radial artery catheterization, and side port monitoring of an indwelling sheath. Each means of monitoring has disadvantages, including time consumption, added risk, and signal dampening due to multiple factors. We sought an alternative approach to monitoring during procedures in the catheterization laboratory. A new technology involving a 330 µm fiberoptic sensor embedded in the wall of a sheath structure was tested against both radial artery catheter and sphygmomanometer readings obtained simultaneous with readings recorded from the pressure sensing system (PSS). Correlations and Bland-Altman analysis were used to determine whether use of the PSS could substitute for these standard techniques. The results indicated highly significant correlations in systolic, diastolic, and mean arterial pressures (MAP) when compared against radial artery catheterization (p<0.0001), and MAP means differed by <4%. Bland-Altman analysis of the data suggested that the sheath measurements can replace a separate radial artery catheter. While less striking, significant correlations were seen when PSS readings were compared against BP cuff readings. The PSS has competitive functionality to that seen with a dedicated radial artery catheter for BP monitoring and is available immediately on sheath insertion without the added risk of radial catheterization. The sensor is structurally separated from the primary sheath lumen and readings are unaffected by device introduction through the primary lumen. Time delays and potential complications from radial artery catheterization are avoided. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  14. Design and Implementation of a Web-based Monitoring System by using EPICS Channel Access Protocol

    International Nuclear Information System (INIS)

    An, Eun Mi; Song, Yong Gi

    2009-01-01

    Proton Engineering Frontier Project (PEFP) has developed a 20MeV proton accelerator, and established a distributed control system based on EPICS for sub-system components such as vacuum unit, beam diagnostics, and power supply system. The control system includes a real-time monitoring and alarm functions. From the aspect of a efficient maintenance of a control system and a additional extension of subsystems, EPICS software framework was adopted. In addition, a control system should be capable of providing an easy access for users and a real-time monitoring on a user screen. Therefore, we have implemented a new web-based monitoring server with several libraries. By adding DB module, the new IOC web monitoring system makes it possible to monitor the system through the web. By integrating EPICS Channel Access (CA) and Database libraries into a Database module, the web-based monitoring system makes it possible to monitor the sub-system status through user's internet browser. In this study, we developed a web based monitoring system by using EPICS IOC (Input Output Controller) with IBM server

  15. The effect of ventricular assist devices on cerebral blood flow and blood pressure fractality

    International Nuclear Information System (INIS)

    Bellapart, Judith; Fraser, John F; Chan, Gregory S H; Tzeng, Yu-Chieh; Ainslie, Philip N; Dunster, Kimble R; Barnett, Adrian G; Boots, Rob

    2011-01-01

    Biological signals often exhibit self-similar or fractal scaling characteristics which may reflect intrinsic adaptability to their underlying physiological system. This study analysed fractal dynamics of cerebral blood flow in patients supported with ventricular assist devices (VAD) to ascertain if sustained modifications of blood pressure waveform affect cerebral blood flow fractality. Simultaneous recordings of arterial blood pressure and cerebral blood flow velocity using transcranial Doppler were obtained from five cardiogenic shock patients supported by VAD, five matched control patients and five healthy subjects. Computation of a fractal scaling exponent (α) at the low-frequency time scale by detrended fluctuation analysis showed that cerebral blood flow velocity exhibited 1/f fractal scaling in both patient groups (α = 0.95 ± 0.09 and 0.97 ± 0.12, respectively) as well as in the healthy subjects (α = 0.86 ± 0.07). In contrast, fluctuation in blood pressure was similar to non-fractal white noise in both patient groups (α = 0.53 ± 0.11 and 0.52 ± 0.09, respectively) but exhibited 1/f scaling in the healthy subjects (α = 0.87 ± 0.04, P < 0.05 compared with the patient groups). The preservation of fractality in cerebral blood flow of VAD patients suggests that normal cardiac pulsation and central perfusion pressure changes are not the integral sources of cerebral blood flow fractality and that intrinsic vascular properties such as cerebral autoregulation may be involved. However, there is a clear difference in the fractal scaling properties of arterial blood pressure between the cardiogenic shock patients and the healthy subjects

  16. A Low-Pressure Oxygen Storage System for Oxygen Supply in Low-Resource Settings.

    Science.gov (United States)

    Rassool, Roger P; Sobott, Bryn A; Peake, David J; Mutetire, Bagayana S; Moschovis, Peter P; Black, Jim Fp

    2017-12-01

    Widespread access to medical oxygen would reduce global pneumonia mortality. Oxygen concentrators are one proposed solution, but they have limitations, in particular vulnerability to electricity fluctuations and failure during blackouts. The low-pressure oxygen storage system addresses these limitations in low-resource settings. This study reports testing of the system in Melbourne, Australia, and nonclinical field testing in Mbarara, Uganda. The system included a power-conditioning unit, a standard oxygen concentrator, and an oxygen store. In Melbourne, pressure and flows were monitored during cycles of filling/emptying, with forced voltage fluctuations. The bladders were tested by increasing pressure until they ruptured. In Mbarara, the system was tested by accelerated cycles of filling/emptying and then run on grid power for 30 d. The low-pressure oxygen storage system performed well, including sustaining a pressure approximately twice the standard working pressure before rupture of the outer bag. Flow of 1.2 L/min was continuously maintained to a simulated patient during 30 d on grid power, despite power failures totaling 2.9% of the total time, with durations of 1-176 min (mean 36.2, median 18.5). The low-pressure oxygen storage system was robust and durable, with accelerated testing equivalent to at least 2 y of operation revealing no visible signs of imminent failure. Despite power cuts, the system continuously provided oxygen, equivalent to the treatment of one child, for 30 d under typical power conditions for sub-Saharan Africa. The low-pressure oxygen storage system is ready for clinical field trials. Copyright © 2017 by Daedalus Enterprises.

  17. Vasopressin and nitroglycerin decrease portal and hepatic venous pressure and hepato-splanchnic blood flow.

    Science.gov (United States)

    Wisén, E; Svennerholm, K; Bown, L S; Houltz, E; Rizell, M; Lundin, S; Ricksten, S-E

    2018-03-26

    Various methods are used to reduce venous blood pressure in the hepato-splanchnic circulation, and hence minimise blood loss during liver surgery. Previous studies show that combination of vasopressin and nitroglycerin reduces portal pressure and flow in patients with portal hypertension, and in this study we investigated this combination in patients with normal portal pressure. In all, 13 patients were studied. Measurements were made twice to confirm baseline (C1 and BL), during vasopressin infusion 4.8 U/h (V), and during vasopressin infusion combined with nitroglycerin infusion (V + N). Portal venous pressure (PVP), hepatic venous pressure (HVP), central haemodynamics and arterial and venous blood gases were obtained at each measuring point, and portal (splanchnic) and hepato-splanchnic blood flow changes were calculated. Vasopressin alone did not affect PVP, whereas HVP increased slightly. In combination with nitroglycerin, PVP decreased from 10.1 ± 1.6 to 8.9 ± 1.3 mmHg (P HVP decreased from 7.9 ± 1.9 to 6.2 ± 1.3 mmHg (P = 0.001). Vasopressin reduced portal blood flow by 47 ± 19% and hepatic venous flow by 11 ± 18%, respectively. Addition of nitroglycerin further reduced portal- and hepatic flow by 55 ± 13% and 30 ± 13%, respectively. Vasopressin alone had minor effects on central haemodynamics, whereas addition of nitroglycerin reduced cardiac index (3.2 ± 0.7 to 2.7 ± 0.5; P < 0.0001). The arterial-portal vein lactate gradient was unaffected. The combination of vasopressin and nitroglycerin decreases portal pressure and hepato-splanchnic blood flow, and could be a potential treatment to reduce bleeding in liver resection surgery. © 2018 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  18. Generation and maintenance of low effective pressures due to fluid flow in fractured rocks

    Science.gov (United States)

    Garagash, D.; Brantut, N.; Schubnel, A.; Bhat, H. S.

    2017-12-01

    The pore fluid pressure is expected to increase with increasing depth in the crust, primarily due to gravity forces. Because direct measurements are impossible beyond a few kilometers depths, the pore pressure gradient is often assumed to be linear (e.g., hydrostatic). However, a number of processes can severely modify the fluid pressure distribution in the crust. Here, we investigate the effect of fluid flow coupled to nonlinear permeability-effective pressure relationship. We performed a set of laboratory fluid flow experiments on thermally cracked Westerly granite at confining pressures up to 200 MPa and pore fluid pressures up to 120 MPa. Fluid flow was generated by imposing very strong pore pressure differences, up to 120 MPa, between the ends of the sample. The vertical fluid pressure distribution inside the sample was inferred by a set of 8 radial strain gauges, and an array of 10 P- and S-wave transducers. When the effective stress is kept near zero at one end of the sample and maintained high at the other end, the steady-state pore pressure profile is nonlinear. The effective stress, as inferred from the strain gauge array, remains close to zero through 2/3 of the sample, and increases sharply near the drained end of the sample. The ultrasonic data are used to build a vertical P- and S-wave velocity structure. The wave velocity profiles are consistent with a nonlinear relationship between wave velocity and effective pressure, as expected in thermally cracked granite. Taken together, our experimental data confirm the theoretical prediction that near zero effective stress can be generated through significant sections of rocks as a response to an imposed fluid flow. This has strong implications for the state of stress of the Earth's crust, especially around major continental transform faults that act as conduits for deep volatiles.

  19. Computerized flow monitors detect small kicks

    Energy Technology Data Exchange (ETDEWEB)

    McCann, D.; White, D. (Sedco Forex, Paris (FR))

    1992-02-24

    This paper reports on a smart alarm system installed on a number of offshore rigs and one land rig which can detect kicks more quickly than conventional systems. This rapid kick detection improves rig safety because the smaller the detected influx, the easier it is to control the well. The extensive computerized monitoring system helps drilling personnel detect fluid influxes and fluid losses before the changes in flow would normally be apparent.

  20. Prediction for the flow distribution and the pressure drop of a plate type fuel assembly

    International Nuclear Information System (INIS)

    Park, Jong Hark; Jo, Dea Sung; Chae, Hee Taek; Lee, Byung Chul

    2011-01-01

    A plate type fuel assembly widely used in many research reactors does not allow the coolant to mix with neighboring fuel channels due to the completely separated flow channels. If there is a serious inequality of coolant distribution among channels, it can reduce thermal-hydraulic safety margin, as well as it can cause a deformation of fuel plates by the pressure difference between neighboring channels, thus the flow uniformity in the fuel assembly should be confirmed. When designing a primary cooling system (PCS), the pressure drop through a reactor core is a dominant value to determine the PCS pump size. The major portion of reactor core pressure drop is caused by the fuel assemblies. However it is not easy to get a reasonable estimation of pressure drop due to the geometric complexity of the fuel assembly and the thin gaps between fuel assemblies. The flow rate through the gap is important part to determine the total flow rate of PCS, so it should be estimated as reasonable as possible. It requires complex and difficult jobs to get useful data. In this study CFD analysis to predict the flow distribution and the pressure drop were conducted on the plate type fuel assembly, which results would be used to be preliminary data to determine the PCS flow rate and to improve the design of a fuel assembly

  1. Calculation of pressure drop and flow redistribution in the core of LMFBR type reactors

    International Nuclear Information System (INIS)

    Botelho, D.A.; Morgado, O.J.

    1985-01-01

    It is studied the flow redistribution through of fuel elements to the pressure drop calculation in the core of sodium cooled reactors. Using the quasi-static formulation of equations of the conservation of mass, energy and momentum, it was developed a computer program to flow redistribution calculations and pressure drop for different power levels and total flow simulating an arbitrary number of channels for sodium flowing . An optimization of the number of sufficient channels for calculations of this nature is done. The method is applied in studies of transients in the same reactor. (M.C.K.) [pt

  2. Moving towards tangible decision-making tools for policy makers: Measuring and monitoring energy access provision

    International Nuclear Information System (INIS)

    Bhanot, Jaya; Jha, Vivek

    2012-01-01

    Access to energy services has been recognised as central to achieving economic growth and sustainable development. However, almost 1.3 billion people in the world still lack access to electricity and 2.7 billion lack access to clean cooking facilities. In this backdrop, the issue of energy access is receiving more interest than ever before and this has brought to the fore, the need for a robust decision support tool for policy makers to measure the progress of energy access provision and also to provide direction for future policy making. The paper studies existing definitions of energy access and identifies the key requirements for an appropriate decision-making tool to measure and monitor energy access provision. In this context the paper assesses the strengths and weaknesses of the metrics currently being used to measure energy access in policy, as well as of contemporary monitoring and evaluation frameworks being used in other sectors. Based on these insights, a dashboard of indicators is proposed as an alternate decision support tool for policy makers to measure energy access. The paper concludes with a discussion on what is needed to operationalise this proposed framework. - Highlights: ► No one indicator or metric can successfully capture progress on energy access. ► A service oriented approach is necessary to measure energy access. ► Socio-economic and political contexts influence success of energy access policies.

  3. Blood Pressure: Does It Have a Daily Pattern?

    Science.gov (United States)

    ... and night. With Sheldon G. Sheps, M.D. Kaplan NM. Ambulatory blood pressure monitoring and white coat ... www.uptodate.com/home. Accessed Feb. 12, 2015. Kaplan NM, et al. Kaplan's Clinical Hypertension. 10th ed. ...

  4. Monitoring operational conditions of vehicle tyre pressure levels and ...

    African Journals Online (AJOL)

    Compliance with vehicle tyre inflation pressure and tread depth standard specifications and legal requirements were monitored by survey study in Kumasi Metropolis, Ghana. The survey covered 400 vehicles, comprising cars (28 %), medium buses (25 %), large capacity buses (15 %) and trucks (32 %). There were wide ...

  5. Quantitative Raman Spectroscopy to monitor microbial metabolism in situ under pressure

    Science.gov (United States)

    Picard, A.; Daniel, I.; Oger, P.

    2006-12-01

    Although high hydrostatic pressure (HHP) biotopes are ubiquitous on Earth, little is known about the metabolism of piezophile organisms. Cell culture under HHP can be technically challenging, and equipment- dependent. In addition, the depressurization step required for analysis can lead to erroneous data. Therefore, to understand how piezophile organisms react to pressure, it is crucial to be able to monitor their activity in situ under HHP. We developed the use of Quantitative Raman Spectroscopy (QRS, 1) to monitor in situ the metabolism of organic molecules. This technique is based on the specific spectral signature of an analyte from which its concentration can be deduced. An application of this technique to the monitoring of alcoholic fermentation by the piezotolerant micro-eucaryote Saccharomyces cerevisiae is presented. Ethanol fermentation from glucose was monitored during 24h from ambient P up to 100 MPa in the low- pressure Diamond Anvil Cell (lpDAC, 2). The experimental compression chamber consisted in a 300 μm-thick Ni gasket in which a 500 μm-diameter hole was drilled. Early-stationnary yeast cells were inoculated into fresh low-fluorescence medium containing 0.15 M of glucose. Ethanol concentration was determined in situ by QRS using the symmetric C-C stretching mode of ethanol at 878 cm-1 normalizing the data to the intensity of the sulfate S-O stretching mode at 980 cm-1. In our setup, the detection limit of ethanol is lower than 0.05 mM with a precision below 1%. At ambient P, ethanol production in the lpDAC and in control experiments proceeds with the same kinetics. Thus, yeast is not affected by its confinement. This is further confirmed by its ability to bud with a generation time similar to control experiments performed in glass tubes at ambient pressure inside the lpDAC. Ethanol production by yeast occurs to at least 65 MPa (3). At 10 MPa, fermentation proceeds 3 times faster than at ambient P. Fermentation rates decrease linearly from 20 to

  6. Home blood pressure monitoring, secure electronic messaging and medication intensification for improving hypertension control: a mediation analysis.

    Science.gov (United States)

    Ralston, J D; Cook, A J; Anderson, M L; Catz, S L; Fishman, P A; Carlson, J; Johnson, R; Green, B B

    2014-01-01

    We evaluated the role of home monitoring, communication with pharmacists, medication intensification, medication adherence and lifestyle factors in contributing to the effectiveness of an intervention to improve blood pressure control in patients with uncontrolled essential hypertension. We performed a mediation analysis of a published randomized trial based on the Chronic Care Model delivered over a secure patient website from June 2005 to December 2007. Study arms analyzed included usual care with a home blood pressure monitor and usual care with home blood pressure monitor and web-based pharmacist care. Mediator measures included secure messaging and telephone encounters; home blood pressure monitoring; medications intensification and adherence and lifestyle factors. Overall fidelity to the Chronic Care Model was assessed with the Patient Assessment of Chronic Care (PACIC) instrument. The primary outcome was percent of participants with blood pressure (BP) <140/90 mm Hg. At 12 months follow-up, patients in the web-based pharmacist care group were more likely to have BP <140/90 mm Hg (55%) compared to patients in the group with home blood pressure monitors only (37%) (p = 0.001). Home blood pressure monitoring accounted for 30.3% of the intervention effect, secure electronic messaging accounted for 96%, and medication intensification for 29.3%. Medication adherence and self-report of fruit and vegetable intake and weight change were not different between the two study groups. The PACIC score accounted for 22.0 % of the main intervention effect. The effect of web-based pharmacist care on improved blood pressure control was explained in part through a combination of home blood pressure monitoring, secure messaging, and antihypertensive medication intensification.

  7. Validation of the dynamics of SDS and RRS flux, flow, pressure and temperature signals using noise analysis technique

    International Nuclear Information System (INIS)

    Glockler, O.; Cooke, D.F.; Tulett, M.V.

    1995-01-01

    In 1992, a program was initiated to establish reactor noise analysis as a practical tool for plant performance monitoring and system diagnostics in Ontario Hydro's CANDU reactors. Since then, various CANDU-specific noise analysis applications have been developed and validated. The noise-based statistical techniques are being successfully applied as powerful troubleshooting and diagnostic tools to a wide variety of actual operational I and C problems. Critical plant components, instrumentation and processes are monitored on a regular basis, and their dynamic characteristics are verified on-power. Recent applications of noise analysis include (1) validating the dynamics of in-core flux detectors (ICFDS) and ion chambers, (2) estimating the prompt fraction ICFDs in noise measurements at full power and in power rundown tests, (3) identifying the cause of excessive signal fluctuations in certain flux detectors, (4) validating the dynamic coupling between liquid zone control signals, (5) detecting and monitoring mechanical vibrations of detector tubes, reactivity devices and fuel channels induced by moderator/coolant flow, (6) estimating the dynamics and response time of RTD temperature signals, (7) isolating the cause of RTD signal anomalies, (8) investigating the source of abnormal flow signal behaviour, (9) estimating the overall response time of flow and pressure signals, (1 0) detecting coolant boiling in fully instrumented fuel channels, (1 1) monitoring moderator circulation via temperature noise, and (12) predicting the performance of shut-off rods. Some of these applications are performed on an as needed basis. The noise analysis program, in the Pickering-B station alone, has saved Ontario Hydro millions of dollars during its first three years. The results of the noise analysis program have been also reviewed by the regulator (Atomic Energy Control Board of Canada) with favorable results. The AECB have expressed interest in Ontario Hydro further exploiting the

  8. Automated contrast medium monitoring system for computed tomography--Intra-institutional audit.

    Science.gov (United States)

    Lauretti, Dario Luca; Neri, Emanuele; Faggioni, Lorenzo; Paolicchi, Fabio; Caramella, Davide; Bartolozzi, Carlo

    2015-12-01

    The aim of this study was to analyze the usage and the data recorded by a RIS-PACS-connected contrast medium (CM) monitoring system (Certegra(®), Bayer Healthcare, Leverkusen, Germany) over 19 months of CT activity. The system used was connected to two dual syringe power injectors (each associated with a 16-row and a high definition 64-row multidetector CT scanner, respectively), allowing to manage contrast medium injection parameters and to send and retrieve CT study-related information via RIS/PACS for any scheduled contrast-enhanced CT examination. The system can handle up to 64 variables and can be accessed via touchscreen by CT operators as well as via a web interface by registered users with three different hierarchy levels. Data related to CM injection parameters (i.e. iodine concentration, volume and flow rate of CM, iodine delivery rate and iodine dose, CM injection pressure, and volume and flow rate of saline), patient weight and height, and type of CT study over a testing period spanning from 1 June 2013 to 10 January 2015 were retrieved from the system. Technical alerts occurred for each injection event (such as system disarm due to technical failure, disarm due to operator's stop, incomplete filling of patient data fields, or excessively high injection pressure), as well as interoperability issues related to data sending and receiving to/from the RIS/PACS were also recorded. During the testing period, the CM monitoring system generated a total of 8609 reports, of which 7629 relative to successful injection events (88.6%). 331 alerts were generated, of which 40 resulted in injection interruption and 291 in CM flow rate limitation due to excessively high injection pressure (>325 psi). Average CM volume and flow rate were 93.73 ± 17.58 mL and 3.53 ± 0.89 mL/s, and contrast injection pressure ranged between 5 and 167 psi. A statistically significant correlation was found between iodine concentration and peak IDR (rs=0.2744, psystems can provide a full

  9. Identification of 3-phase flow patterns of heavy oil from pressure drop and flow rate data

    Energy Technology Data Exchange (ETDEWEB)

    Pacheco, F.; Bannwart, A.C.; Mendes, J.R.P. [Campinas State Univ., Sao Paulo (Brazil); Serapiao, A.B.S. [Sao Paulo State Univ., Sao Paulo (Brazil)

    2008-07-01

    Pipe flow of oil-gas-water mixtures poses a complex thermo-fluid dynamical problem. This paper examined the relationship between phase flow rates, flow pattern identification, and pressure drop in 3-phase water-assisted heavy oil in the presence of a gaseous phase. An artificial intelligence program called a support vector machine (SVM) was used to determine relevant parameters for flow pattern classification. Data from a 3-phase flow of heavy oil with gas and water in a vertical pipe was used in the study. The data were used to train the machine, which then predicted the flow pattern of the remaining data. Tests with different parameters and training data were then performed. The study showed that the proposed SVM flow pattern identification process accurately predicted flow patterns. It was concluded that the SVM took a relatively short amount of time to train. Future research is needed to apply the tool to larger flow datasets. 5 refs., 1 tab., 2 figs.

  10. Identification of two-phase flow pattern by using specific spatial frequency of differential pressure signal

    International Nuclear Information System (INIS)

    Han Bin; Tong Yunxian; Wu Shaorong

    1992-11-01

    It is a classical method by using analysis of differential pressure fluctuation signal to identify two-phase flow pattern. The method which uses trait peak in the frequency-domain will result confusion between bubble flow and intermittent flow due to the influence of gas speed. Considering the spatial geometric significance of two-phase slow patterns and using the differential pressure gauge as a sensor, the Strouhal number 'Sr' is taken as the basis for distinguishing flow patterns. Using Strouhal number 'Sr' to identify flow pattern has clear physical meaning. The experimental results using the spatial analytical technique to measure the flow pattern are also given

  11. Regional cerebral blood flow and CSF pressures during Cushing response induced by a supratentorial expanding mass

    International Nuclear Information System (INIS)

    Schrader, H.; Zwetnow, N.N.; Moerkrid, L.

    1985-01-01

    In order to delineate the critical blood flow pattern during the Cushing response in intracranial hypertension, regional cerebral blood flow was measured with radioactive microspheres in 12 anesthetized dogs at respiratory arrest caused either by expansion of an epidural supratentorial balloon or by cisternal infusion. Regional cerebrospinal fluid pressures were recorded and the local cerebral perfusion pressure calculated in various cerebrospinal compartments. In the 8 dogs of the balloon expansion group, the systemic arterial pressure was unmanipulated in 4, while it was kept at a constant low level (48 and 70 mm Hg) in 2 dogs and, in another 2 dogs, at a constant high level (150 and 160 mm Hg) induced by infusion of Aramine. At respiratory arrest, regional cerebral blood flow had a stereotyped pattern and was largely independent of the blood pressure level. In contrast, concomitant pressure gradients between the various cerebrospinal compartments varied markedly in the 3 animal groups increasing with higher arterial pressure. Flow decreased by 85-100% supratentorially and by 70-100% in the upper brain stem down to the level of the upper pons, while changes in the lower brain stem were minor, on the average 25%. When intracranial pressure was raised by cisternal infusion in 4 dogs, the supratentorial blood flow pattern at respiratory arrest was appriximately similar to the flow pattern in the balloon inflation group. However, blood flow decreased markedly (74-85%) also in the lower brain stem. The results constitute another argument in favour of the Cushing response in supratentorial expansion being caused by ischemia in the brain stem. The critical ischemic region seems to be located rostrally to the oblongate medulla, probably in the pons. (author)

  12. KETAMINE-MEDETOMIDINE AND KETAMINE-MEDETOMIDINE-MIDAZOLAM ANESTHESIA IN CAPTIVE CHEETAHS (ACINONYX JUBATUS)-COMPARISON OF BLOOD PRESSURE AND KIDNEY BLOOD FLOW.

    Science.gov (United States)

    Stagegaard, Julia; Hørlyck, Arne; Hydeskov, Helle B; Bertelsen, Mads F

    2017-06-01

    Six clinically healthy captive cheetahs ( Acinonyx jubatus ) were anesthetized twice using two different drug combinations to investigate if blood pressure and kidney blood flow are affected by medetomidine dosage. Protocol KM (2.0 mg/kg ketamine and 0.05 mg/kg medetomidine) was compared with protocol KMM (2.0 mg/kg ketamine, 0.02 mg/kg medetomidine, and 0.1 mg/kg midazolam). Heart rate (HR), respiratory rate (RR), body temperature, end-tidal carbon dioxide pressure (ETCO 2 ), and anesthetic depth were monitored every 10 min. Noninvasive mean (MAP), systolic (SAP), and diastolic (DAP) arterial blood pressure were measured, and Duplex Doppler ultrasonography was performed on the kidneys. The mean arterial resistive index (RI) was determined and the pulse pressure index (PPI) was calculated, as indicators for kidney blood flow. There were no significant differences in induction and recovery times. MAP was significantly higher with KM than KMM at 35 min, and in both protocols decreased significantly after atipamezole administration. DAP was significantly higher at 25 and 35 min in animals anesthetized with KM; it also decreased significantly with both protocols after atipamezole administration. The PPI was significantly lower throughout the procedure with KM, and with both protocols increased significantly after atipamezole administration. Both the higher blood pressure and the reduced PPI with KM were likely a direct effect of the higher medetomidine dosage, and these findings indicate that lower medetomidine dosages might reduce hypertension and lead to a better PPI in cheetah immobilization.

  13. A study of the blood flow restriction pressure of a tourniquet system to facilitate development of a system that can prevent musculoskeletal complications.

    Science.gov (United States)

    Maeda, Hiroyuki; Iwase, Hideaki; Kanda, Akio; Morohashi, Itaru; Kaneko, Kazuo; Maeda, Mutsuhiro; Kakinuma, Yuki; Takei, Yusuke; Amemiya, Shota; Mitsui, Kazuyuki

    2017-01-01

    After an emergency or disaster, subsequent trauma can cause severe bleeding and this can often prove fatal, so promptly stopping that bleeding is crucial to preventing avoidable trauma deaths. A tourniquet is often used to restrict blood flow to an extremity. In operation and hospital, the tourniquet systems currently in use are pneumatically actuated by an air compressor, so they must have a steady power supply. These devices have several drawbacks: they vibrate and are noisy since they are pneumatically actuated and they are far from portable since they are large and heavy. Presumably, the drawbacks of pneumatic tourniquets could be overcome by developing a small, lightweight, vibration-free, quiet, and battery-powered tourniquet system. The current study built a small, vibration-free electrohydrodynamic (EHD) pump and then used that pump to restrict blood flow to the leg of rats in an experiment. This study explored the optimal conditions for effective restriction of blood flow by assessing biochemical and musculoskeletal complications following the restriction of blood flow, and this study also examined whether or not an EHD pump could be used to actuate a tourniquet system. A tourniquet cuff (width 12 mm × length 150 mm, material: polyolefin) was placed on the thigh of Wistar rats and pressure was applied for 2 hours by a device that uses EHD phenomena to generate pressure (an EHD pump). Animals were divided into four groups based on how much compressive pressure was applied with a tourniquet: 40 kPa (300 mm Hg, n = 13), 30 kPa (225 mm Hg, n = 12), 20 kPa (150 mm Hg, n = 15), or 0 kPa (controls, n = 25). Tissue oxygen saturation (regional oxygen saturation, denoted here as rSO 2 ) was measured to assess the restriction of blood flow. To assess behavior once blood flow resumed, animal activity was monitored for third day and the amount of movement was counted with digital counters. Body weight was measured before and after the behavioral experiment, and

  14. Development of Remote Monitoring and a Control System Based on PLC and WebAccess for Learning Mechatronics

    OpenAIRE

    Wen-Jye Shyr; Te-Jen Su; Chia-Ming Lin

    2013-01-01

    This study develops a novel method for learning mechatronics using remote monitoring and control, based on a programmable logic controller (PLC) and WebAccess. A mechatronics module, a Web‐CAM and a PLC were integrated with WebAccess software to organize a remote laboratory. The proposed system enables users to access the Internet for remote monitoring and control of the mechatronics module via a web browser, thereby enhancing work flexibility by enabling personnel to control mechatronics equ...

  15. Experimental apparatus with full optical access for combustion experiments with laminar flames from a single circular nozzle at elevated pressures.

    Science.gov (United States)

    Joo, Peter H; Gao, Jinlong; Li, Zhongshan; Aldén, Marcus

    2015-03-01

    The design and features of a high pressure chamber and burner that is suitable for combustion experiments at elevated pressures are presented. The high pressure combustion apparatus utilizes a high pressure burner that is comprised of a chamber burner module and an easily accessible interchangeable burner module to add to its flexibility. The burner is well suited to study both premixed and non-premixed flames. The optical access to the chamber is provided through four viewports for direct visual observations and optical-based diagnostic techniques. Auxiliary features include numerous access ports and electrical connections and as a result, the combustion apparatus is also suitable to work with plasmas and liquid fuels. Images of methane flames at elevated pressures up to 25 atm and preliminary results of optical-based measurements demonstrate the suitability of the high pressure experimental apparatus for combustion experiments.

  16. Variable disparity estimation based intermediate view reconstruction in dynamic flow allocation over EPON-based access networks

    Science.gov (United States)

    Bae, Kyung-Hoon; Lee, Jungjoon; Kim, Eun-Soo

    2008-06-01

    In this paper, a variable disparity estimation (VDE)-based intermediate view reconstruction (IVR) in dynamic flow allocation (DFA) over an Ethernet passive optical network (EPON)-based access network is proposed. In the proposed system, the stereoscopic images are estimated by a variable block-matching algorithm (VBMA), and they are transmitted to the receiver through DFA over EPON. This scheme improves a priority-based access network by converting it to a flow-based access network with a new access mechanism and scheduling algorithm, and then 16-view images are synthesized by the IVR using VDE. Some experimental results indicate that the proposed system improves the peak-signal-to-noise ratio (PSNR) to as high as 4.86 dB and reduces the processing time to 3.52 s. Additionally, the network service provider can provide upper limits of transmission delays by the flow. The modeling and simulation results, including mathematical analyses, from this scheme are also provided.

  17. Research on Segmentation Monitoring Control of IA-RWA Algorithm with Probe Flow

    Science.gov (United States)

    Ren, Danping; Guo, Kun; Yao, Qiuyan; Zhao, Jijun

    2018-04-01

    The impairment-aware routing and wavelength assignment algorithm with probe flow (P-IA-RWA) can make an accurate estimation for the transmission quality of the link when the connection request comes. But it also causes some problems. The probe flow data introduced in the P-IA-RWA algorithm can result in the competition for wavelength resources. In order to reduce the competition and the blocking probability of the network, a new P-IA-RWA algorithm with segmentation monitoring-control mechanism (SMC-P-IA-RWA) is proposed. The algorithm would reduce the holding time of network resources for the probe flow. It segments the candidate path suitably for the data transmitting. And the transmission quality of the probe flow sent by the source node will be monitored in the endpoint of each segment. The transmission quality of data can also be monitored, so as to make the appropriate treatment to avoid the unnecessary probe flow. The simulation results show that the proposed SMC-P-IA-RWA algorithm can effectively reduce the blocking probability. It brings a better solution to the competition for resources between the probe flow and the main data to be transferred. And it is more suitable for scheduling control in the large-scale network.

  18. Ambulatory blood pressure monitoring in daily clinical practice - the Spanish ABPM Registry experience.

    Science.gov (United States)

    Gorostidi, Manuel; Banegas, José R; de la Sierra, Alejandro; Vinyoles, Ernest; Segura, Julián; Ruilope, Luis M

    2016-01-01

    Many patients are hypertensive at the medical settings but show normal blood pressure out of the doctor's office, and are classified as white-coat hypertensives. On the other hand, many patients with controlled hypertension at the clinic show ambulatory blood pressure levels above the thresholds considered for an adequate blood pressure control, known as having masked hypertension. Using data from the Spanish Ambulatory Blood Pressure Monitoring Registry (Spanish ABPM Registry), a national program developed to promote the use of the ambulatory technique for hypertension management in daily practice, we have reviewed the main strengths of this approach, that is the ability to detect discrepancies of blood pressure status with respect to office blood pressure measurement, and to better assess accurate rates of hypertension control. White-coat hypertension within patients with elevated office blood pressure, and masked hypertension within office-controlled patients affected one of three patients in each office status. On the other hand, rates of ambulatory blood pressure control (50%) doubled those of office blood pressure control (25%), still remaining half the patients uncontrolled. We think that a systematic use of ambulatory blood pressure monitoring, and strategies to improve blood pressure control constitute key priorities in hypertension management. © 2015 Stichting European Society for Clinical Investigation Journal Foundation.

  19. Noninvasive estimation of pulmonary arterial pressure by analysis of pulmonary blood-flow distribution

    International Nuclear Information System (INIS)

    Konstam, M.A.; Strauss, H.W.; Alpert, N.M.; Miller, S.W.; Murphy, R.X.; Greene, R.E.; McKusick, K.A.

    1979-01-01

    To determine whether a correlation exists between pulmonary arterial (PA) pressure (P/sub a/) and the distribution of pulmonary blood flow, this distribution was measured in four upright dogs in the control state and during intravenous infusions of epinephrine or prostaglandin F/sub 2α/. During suspension of respiration, 15 mCi of Xe-133 were injected intravenously, and perfusion and equilibration lung images were recorded with a scintillation camera. The procedure was performed several times on each dog, with and without pharmacological elevation of PA pressure by 5 to 50 cm H 2 O. For each scintigram, the relative blood flow per unit ventilated lung volume (F) was plotted against centimeters above the hilum (h). Pulmonary arterial pressure was derived from each curve, assuming the relation F = B(P/sub a/ - hD) 2 , where B = constant and D = specific gravity of blood. Calculated PA pressure correlated strongly (r = 0.83) with measured PA pressure, suggesting a possible means of noninvasive estimation of PA pressure

  20. Cerebral blood flow in normal pressure hydrocephalus

    International Nuclear Information System (INIS)

    Mamo, H.L.; Meric, P.C.; Ponsin, J.C.; Rey, A.C.; Luft, A.G.; Seylaz, J.A.

    1987-01-01

    A xenon-133 method was used to measure cerebral blood flow (CBF) before and after cerebrospinal fluid (CSF) removal in patients with normal pressure hydrocephalus (NPH). Preliminary results suggested that shunting should be performed on patients whose CBF increased after CSF removal. There was a significant increase in CBF in patients with NPH, which was confirmed by the favorable outcome of 88% of patients shunted. The majority of patients with senile and presenile dementia showed a decrease or no change in CBF after CSF removal. It is suggested that although changes in CBF and clinical symptoms of NPH may have the same cause, i.e., changes in the cerebral intraparenchymal pressure, there is no simple direct relation between these two events. The mechanism underlying the loss of autoregulation observed in NPH is also discussed

  1. Heat transfer and pressure drop in flow boiling in microchannels

    CERN Document Server

    Saha, Sujoy Kumar

    2016-01-01

    This Brief addresses the phenomena of heat transfer and pressure drop in flow boiling in micro channels occurring in high heat flux electronic cooling. A companion edition in the Springer Brief Subseries on Thermal Engineering and Applied Science to “Critical Heat Flux in Flow Boiling in Micro channels,” by the same author team, this volume is idea for professionals, researchers and graduate students concerned with electronic cooling.

  2. Flow regime visualization and pressure drops of HFO-1234yf, R-134a and R-410A during downward two-phase flow in vertical return bends

    International Nuclear Information System (INIS)

    Padilla, Miguel; Revellin, Rémi; Wallet, Jérémy; Bonjour, Jocelyn

    2013-01-01

    Highlights: ► Visual observation of two-phase flow regimes during downward flow in a return bend. ► Bubble and vapor slug dynamical behaviors in downward slug flow are reported. ► Perturbation lengths up- and downstream of the return bend have been investigated. ► Measurement of 285 pressure drop data points for HFO-1234yf, R-134a and R-410A. -- Abstract: This paper provides a qualitative visual observation of the two-phase flow patterns for HFO-1234yf and R-134a during downward flow in a vertical 6.7 mm inner diameter glass return bend. The different flow regimes observed are: slug, intermittent and annular flows. Bubble and vapor slug dynamical behaviors in downward slug flow are reported for HFO-1234yf. In addition, to determine the perturbation lengths up- and downstream of the return bend, the total pressure drop has been measured at different pressure tap location up- and downstream of the singularity. Furthermore, 285 pressure drop data points measured for two-phase flow of HFO-1234yf, R-134a and R-410A in vertical downward flow return bends are presented. The flow behavior in the return bend, which is subjected to the complex combined actions of gravity and centrifugal force was expressed in terms of the vapor Froude number. This experimental pressure drop database, which is included in the appendix, is compared to four well-known prediction methods available in the literature

  3. Cerebral blood flow changes in response to elevated intracranial pressure in rabbits and bluefish: a comparative study.

    Science.gov (United States)

    Beiner, J M; Olgivy, C S; DuBois, A B

    1997-03-01

    In mammals, the cerebrovascular response to increases in intracranial pressure may take the form of the Cushing response, which includes increased mean systemic arterial pressure, bradycardia and diminished respirations. The mechanism, effect and value of these responses are debated. Using laser-Doppler flowmetry to measure cerebral blood flow, we analyzed the cardiovascular responses to intracranial pressure raised by epidural infusion of mock cerebrospinal fluid in the bluefish and in the rabbit, and compare the results. A decline in cerebral blood flow preceding a rise in mean systemic arterial pressure was observed in both species. Unlike bluefish, rabbits exhibit a threshold of intracranial pressure below which cerebral blood flow was maintained and no cardiovascular changes were observed. The difference in response between the two species was due to the presence of an active autoregulatory system in the cerebral tissue of rabbits and its absence in bluefish. For both species studied, the stimulus for the Cushing response seems to be a decrement in cerebral blood flow. The resulting increase in the mean systemic arterial pressure restores cerebral blood flow to levels approaching controls.

  4. Ambulatory blood pressure monitoring in patients with hyperthyroidism before the introduction of therapy and on therapy

    Directory of Open Access Journals (Sweden)

    Stojanović Miloš

    2017-01-01

    Full Text Available The increased secretion of thyroid gland hormones affects the cardiovascular system by increasing heart rate and often by increasing systolic and diastolic blood pressure. We examined the influence of elevated thyroid hormone on blood pressure. Blood pressure monitoring was performed prior to the introduction of therapy in people with increased FT4 and on therapy when FT4 was in the normal range. We analyzed 32 people, of which 26 women had normal blood pressure values measured by blood pressure monitoring. Average age 45 and body mass index 27 kg/m2. Blood pressure was measured by monitoring blood pressure for 24 hours. On average, before the introduction of the therapy, it was 133/83 mmHg P 96 / min. The blood pressure on average on therapy with tireosuppressive was 128/82 mmHg P 74 / min. The Wilcoxon-Mann-Whitney paired test shows a significant P <0.05 higher systolic blood pressure and pulse rate during the day and night before the treatment, when FT4 was higher, than the time when medication was taking, when the FT4 was in the normal range. No significant difference was found for diastolic blood pressure before the introduction of therapy and during therapy with tireosuppressives. When values of FT4 are increased, monitoring of blood pressure shows significantly higher values of systolic blood pressure and pulse during day and night compared to systolic blood pressure and pulse values when FT4 is in the normal range.

  5. Noninvasive 24-hour ambulatory arterial blood pressure monitoring in cirrhosis

    DEFF Research Database (Denmark)

    Møller, Søren; Wiinberg, N; Henriksen, Jens Henrik

    1995-01-01

    Cirrhotic patients have disturbed systemic hemodynamics with reduced arterial blood pressure, but this has not been investigated during daily activity and sleep. Systolic (SBP), diastolic (DBP), and mean arterial blood pressure (MAP), and heart rate (HR) were measured by an automatic ambulant...... device for monitoring blood pressure in 35 patients with cirrhosis and 35 healthy matched controls. During the daytime, SBP, DBP, and MAP were significantly lower in the patients than in the controls (median 118 vs. 127; 70 vs. 78; 86 vs. 94 mm Hg, P blood pressures...... were almost similar in the two groups (108 vs. 110; 65 vs. 67; 78 vs. 82 mm Hg, NS). Conversely, HR was significantly higher in the patients both in the daytime (86 vs. 72/min, P blood pressure and HR from daytime...

  6. A continuous-flow, high-throughput, high-pressure parahydrogen converter for hyperpolarization in a clinical setting.

    Science.gov (United States)

    Hövener, Jan-Bernd; Bär, Sébastien; Leupold, Jochen; Jenne, Klaus; Leibfritz, Dieter; Hennig, Jürgen; Duckett, Simon B; von Elverfeldt, Dominik

    2013-02-01

    Pure parahydrogen (pH(2) ) is the prerequisite for optimal pH(2) -based hyperpolarization experiments, promising approaches to access the hidden orders of magnitude of MR signals. pH(2) production on-site in medical research centers is vital for the proliferation of these technologies in the life sciences. However, previously suggested designs do not meet our requirements for safety or production performance (flow rate, pressure or enrichment). In this article, we present the safety concept, design and installation of a pH(2) converter, operated in a clinical setting. The apparatus produces a continuous flow of four standard liters per minute of ≈98% enriched pH(2) at a pressure maximum of 50 bar. The entire production cycle, including cleaning and cooling to 25 K, takes less than 5 h, only ≈45 min of which are required for actual pH(2) conversion. A fast and simple quantification procedure is described. The lifetimes of pH(2) in a glass vial and aluminum storage cylinder are measured to be T(1C) (glass vial) =822 ± 29 min and T(1C) (Al cylinder) =129 ± 36 days, thus providing sufficiently long storage intervals and allowing the application of pH(2) on demand. A dependence of line width on pH(2) enrichment is observed. As examples, (1) H hyperpolarization of pyridine and (13) C hyperpolarization of hydroxyethylpropionate are presented. Copyright © 2012 John Wiley & Sons, Ltd.

  7. Measuring and monitoring equity in access to deceased donor kidney transplantation.

    Science.gov (United States)

    Stewart, D E; Wilk, A R; Toll, A E; Harper, A M; Lehman, R R; Robinson, A M; Noreen, S A; Edwards, E B; Klassen, D K

    2018-05-07

    The Organ Procurement and Transplantation Network monitors progress toward strategic goals such as increasing the number of transplants and improving waitlisted patient, living donor, and transplant recipient outcomes. However, a methodology for assessing system performance in providing equity in access to transplants was lacking. We present a novel approach for quantifying the degree of disparity in access to deceased donor kidney transplants among waitlisted patients and determine which factors are most associated with disparities. A Poisson rate regression model was built for each of 29 quarterly, period-prevalent cohorts (January 1, 2010-March 31, 2017; 5 years pre-kidney allocation system [KAS], 2 years post-KAS) of active kidney waiting list registrations. Inequity was quantified as the outlier-robust standard deviation (SD w ) of predicted transplant rates (log scale) among registrations, after "discounting" for intentional, policy-induced disparities (eg, pediatric priority) by holding such factors constant. The overall SD w declined by 40% after KAS implementation, suggesting substantially increased equity. Risk-adjusted, factor-specific disparities were measured with the SD w after holding all other factors constant. Disparities associated with calculated panel-reactive antibodies decreased sharply. Donor service area was the factor most associated with access disparities post-KAS. This methodology will help the transplant community evaluate tradeoffs between equity and utility-centric goals when considering new policies and help monitor equity in access as policies change. © 2018 The American Society of Transplantation and the American Society of Transplant Surgeons.

  8. Boiling on a tube bundle: heat transfer, pressure drop and flow patterns

    International Nuclear Information System (INIS)

    Royen Van, E.

    2011-11-01

    The complexity of two-phase flow boiling on a tube bundle presents many challenges to the understanding of the physical phenomena taking place. It is important to quantify these numerous heat flow mechanisms in order to better describe the performance of tube bundles as a function of the operational conditions. In the present study, the bundle boiling facility at the Laboratory of Heat and Mass Transfer (LTCM) was modified to obtain high-speed videos to characterise the two-phase regimes and some bubble dynamics of the boiling process. It was then used to measure heat transfer on single tubes and in bundle boiling conditions. Pressure drop measurements were also made during adiabatic and diabatic bundle conditions. New enhanced boiling tubes from Wolverine Tube Inc. (Turbo-B5) and the Wieland-Werke AG (Gewa-B5) were investigated using R134a and R236fa as test fluids. The tests were carried out at saturation temperatures T sat of 5 °C and 15 °C, mass flow rates from 4 to 35 kg/m 2 s and heat fluxes from 15 to 70 kW/m 2 , typical of actual operating conditions. The flow pattern investigation was conducted using visual observations from a borescope inserted in the middle of the bundle. Measurements of the light attenuation of a laser beam through the intertube two-phase flow and local pressure fluctuations with piezo-electric pressure transducers were also taken to further help in characterising the complex flow. Pressure drop measurements and data reduction procedures were revised and used to develop new, improved frictional pressure drop prediction methods for adiabatic and diabatic two-phase conditions. The physical phenomena governing the enhanced tube evaporation process and their effects on the performance of tube bundles were investigated and insight gained. A new method based on a theoretical analysis of thin film evaporation was used to propose a new correlating parameter. A large new database of local heat transfer coefficients were obtained and then

  9. Relation between plasma plume density and gas flow velocity in atmospheric pressure plasma

    International Nuclear Information System (INIS)

    Yambe, Kiyoyuki; Taka, Shogo; Ogura, Kazuo

    2014-01-01

    We have studied atmospheric pressure plasma generated using a quartz tube, helium gas, and copper foil electrode by applying RF high voltage. The atmospheric pressure plasma in the form of a bullet is released as a plume into the atmosphere. To study the properties of the plasma plume, the plasma plume current is estimated from the difference in currents on the circuit, and the drift velocity is measured using a photodetector. The relation of the plasma plume density n plu , which is estimated from the current and the drift velocity, and the gas flow velocity v gas is examined. It is found that the dependence of the density on the gas flow velocity has relations of n plu ∝ log(v gas ). However, the plasma plume density in the laminar flow is higher than that in the turbulent flow. Consequently, in the laminar flow, the density increases with increasing the gas flow velocity

  10. Air-Flow-Driven Triboelectric Nanogenerators for Self-Powered Real-Time Respiratory Monitoring.

    Science.gov (United States)

    Wang, Meng; Zhang, Jiahao; Tang, Yingjie; Li, Jun; Zhang, Baosen; Liang, Erjun; Mao, Yanchao; Wang, Xudong

    2018-06-04

    Respiration is one of the most important vital signs of humans, and respiratory monitoring plays an important role in physical health management. A low-cost and convenient real-time respiratory monitoring system is extremely desirable. In this work, we demonstrated an air-flow-driven triboelectric nanogenerator (TENG) for self-powered real-time respiratory monitoring by converting mechanical energy of human respiration into electric output signals. The operation of the TENG was based on the air-flow-driven vibration of a flexible nanostructured polytetrafluoroethylene (n-PTFE) thin film in an acrylic tube. This TENG can generate distinct real-time electric signals when exposed to the air flow from different breath behaviors. It was also found that the accumulative charge transferred in breath sensing corresponds well to the total volume of air exchanged during the respiration process. Based on this TENG device, an intelligent wireless respiratory monitoring and alert system was further developed, which used the TENG signal to directly trigger a wireless alarm or dial a cell phone to provide timely alerts in response to breath behavior changes. This research offers a promising solution for developing self-powered real-time respiratory monitoring devices.

  11. Design and Evaluation of a Proxy-Based Monitoring System for OpenFlow Networks.

    Science.gov (United States)

    Taniguchi, Yoshiaki; Tsutsumi, Hiroaki; Iguchi, Nobukazu; Watanabe, Kenzi

    2016-01-01

    Software-Defined Networking (SDN) has attracted attention along with the popularization of cloud environment and server virtualization. In SDN, the control plane and the data plane are decoupled so that the logical topology and routing control can be configured dynamically depending on network conditions. To obtain network conditions precisely, a network monitoring mechanism is necessary. In this paper, we focus on OpenFlow which is a core technology to realize SDN. We propose, design, implement, and evaluate a network monitoring system for OpenFlow networks. Our proposed system acts as a proxy between an OpenFlow controller and OpenFlow switches. Through experimental evaluations, we confirm that our proposed system can capture packets and monitor traffic information depending on administrator's configuration. In addition, we show that our proposed system does not influence significant performance degradation to overall network performance.

  12. Design and Evaluation of a Proxy-Based Monitoring System for OpenFlow Networks

    Directory of Open Access Journals (Sweden)

    Yoshiaki Taniguchi

    2016-01-01

    Full Text Available Software-Defined Networking (SDN has attracted attention along with the popularization of cloud environment and server virtualization. In SDN, the control plane and the data plane are decoupled so that the logical topology and routing control can be configured dynamically depending on network conditions. To obtain network conditions precisely, a network monitoring mechanism is necessary. In this paper, we focus on OpenFlow which is a core technology to realize SDN. We propose, design, implement, and evaluate a network monitoring system for OpenFlow networks. Our proposed system acts as a proxy between an OpenFlow controller and OpenFlow switches. Through experimental evaluations, we confirm that our proposed system can capture packets and monitor traffic information depending on administrator’s configuration. In addition, we show that our proposed system does not influence significant performance degradation to overall network performance.

  13. 40 CFR 60.274 - Monitoring of operations.

    Science.gov (United States)

    2010-07-01

    ... system is in use, and a furnace static pressure gauge is installed according to paragraph (f) of this... volumetric flow rate through each separately ducted hood; or install, calibrate, and maintain a monitoring device that continuously records the volumetric flow rate at the control device inlet and check and...

  14. Technical advances in flow cytometry-based diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria

    Science.gov (United States)

    Correia, Rodolfo Patussi; Bento, Laiz Cameirão; Bortolucci, Ana Carolina Apelle; Alexandre, Anderson Marega; Vaz, Andressa da Costa; Schimidell, Daniela; Pedro, Eduardo de Carvalho; Perin, Fabricio Simões; Nozawa, Sonia Tsukasa; Mendes, Cláudio Ernesto Albers; Barroso, Rodrigo de Souza; Bacal, Nydia Strachman

    2016-01-01

    ABSTRACT Objective: To discuss the implementation of technical advances in laboratory diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria for validation of high-sensitivity flow cytometry protocols. Methods: A retrospective study based on analysis of laboratory data from 745 patient samples submitted to flow cytometry for diagnosis and/or monitoring of paroxysmal nocturnal hemoglobinuria. Results: Implementation of technical advances reduced test costs and improved flow cytometry resolution for paroxysmal nocturnal hemoglobinuria clone detection. Conclusion: High-sensitivity flow cytometry allowed more sensitive determination of paroxysmal nocturnal hemoglobinuria clone type and size, particularly in samples with small clones. PMID:27759825

  15. Monitoring of injected CO2 at two commercial geologic storage sites with significant pressure depletion and/or re-pressurization histories: A case study

    Directory of Open Access Journals (Sweden)

    Dayanand Saini

    2017-03-01

    The monitoring technologies that have been used/deployed/tested at both the normally pressured West Hastings and the subnormally pressured Bell Creek storage sites appear to adequately address any of the potential “out of zone migration” of injected CO2 at these sites. It would be interesting to see if any of the collected monitoring data at the West Hastings and the Bell Creek storage sites could also be used in future to better understand the viability of initially subnormally pressured and subsequently depleted and re-pressurized oil fields as secure geologic CO2 storage sites with relatively large storage CO2 capacities compared to the depleted and re-pressurized oil fields that were initially discovered as normally pressured.

  16. Developing A National Groundwater-Monitoring Network In Korea

    Science.gov (United States)

    Kim, N. J.; Cho, M. J.; Woo, N. C.

    1995-04-01

    Since the 1960's, the groundwater resources of Korea have been developed without a proper regulatory system for monitoring and preservation, resulting in significant source depletion, land subsidence, water contamination, and sea-water intrusion. With the activation of the "Groundwater Law" in June 1994, the government initiated a project to develop a groundwater-monitoring network to describe general groundwater quality, to define its long-term changes, and to identify major factors affecting changes in groundwater quality and yield. In selecting monitoring locations nationwide, criteria considered are 1) spatial distribution, 2) aquifer characteristics of hydrogeologic units, 3) local groundwater flow regime, 4) linkage with surface hydrology observations, 5) site accessibility, and 6) financial situations. A total of 310 sites in 78 small hydrologic basins were selected to compose the monitoring network. Installation of monitoring wells is scheduled to start in 1995 for 15 sites; the remainder are scheduled to be completed by 2001. At each site, a nest of monitoring wells was designed; shallow and deep groundwater will be monitored for water temperature, pH, EC, DO and TDS every month. Water-level fluctuations will also be measured by automatic recorders equipped with pressure transducers. As a next step, the government plans to develop a groundwater-database management system, which could be linked with surface hydrologic data.

  17. Downstream pressure and elastic wall reflection of droplet flow in a T-junction microchannel

    Science.gov (United States)

    Pang, Yan; Liu, Zhaomiao; Zhao, Fuwang

    2016-08-01

    This paper discusses pressure variation on a wall during the process of liquid flow and droplet formation in a T-junction microchannel. Relevant pressure in the channel, deformation of the elastic wall, and responses of the droplet generation are analyzed using a numerical method. The pressure difference between the continuous and dispersed phases can indicate the droplet-generation period. The pressure along the channel of the droplet flow is affected by the position of droplets, droplet-generation period, and droplet escape from the outlet. The varying pressures along the channel cause a nonuniform deformation of the wall when they are elastic. The deformation is a vibration and has the same period as the droplet generation arising from the process of droplet formation.

  18. Separation of ions in nanofluidic channels with combined pressure-driven and electro-osmotic flow.

    Science.gov (United States)

    Gillespie, Dirk; Pennathur, Sumita

    2013-03-05

    Separation of ionic species with the same electrophoretic mobility but different valence in electrolyte systems can occur within nanometer-scale channels with finite electrical double layers (EDLs). This is because EDL thicknesses are a significant fraction of slit height in such channels and can create transverse analyte concentration profiles that allow for unique separation modalities when combined with axial fluid flow. Previous work has shown such separation to occur using either pressure-driven flow or electro-osmotic flow separately. Here, we develop a Poisson-Boltzmann model to compare the separation of such ions using the combination of both pressure-driven and electro-osmotic flow. Applying a pressure gradient in the opposite direction of electro-osmotic flow can allow for zero or infinite retention of analyte species, which we investigate using three different wall boundary conditions. Furthermore, we determine conditions in fused silica nanochannels with which to generate optimal separation between two analytes of different charge but the same mobility. We also give simple rules of thumb to achieve the best separation efficacy in nanochannel systems.

  19. In vitro validation of a Pitot-based flow meter for the measurement of respiratory volume and flow in large animal anaesthesia.

    Science.gov (United States)

    Moens, Yves P S; Gootjes, Peter; Ionita, Jean-Claude; Heinonen, Erkki; Schatzmann, Urs

    2009-05-01

    To remodel and validate commercially available monitors and their Pitot tube-based flow sensors for use in large animals, using in vitro techniques. Prospective, in vitro experiment. Both the original and the remodelled sensor were studied with a reference flow generator. Measurements were taken of the static flow-pressure relationship and linearity of the flow signal. Sensor airway resistance was calculated. Following recalibration of the host monitor, volumes ranging from 1 to 7 L were generated by a calibration syringe, and bias and precision of spirometric volume was determined. Where manual recalibration was not available, a conversion factor for volume measurement was determined. The influence of gas composition mixture and peak flow on the conversion factor was studied. Both the original and the remodelled sensor showed similar static flow-pressure relationships and linearity of the flow signal. Mean bias (%) of displayed values compared with the reference volume of 3, 5 and 7 L varied between -0.4% and +2.4%, and this was significantly smaller than that for 1 L (4.8% to +5.0%). Conversion factors for 3, 5 and 7 L were very similar (mean 6.00 +/- 0.2, range 5.91-6.06) and were not significantly influenced by the gas mixture used. Increasing peak flow caused a small decrease in the conversion factor. Volume measurement error and conversion factors for inspiration and expiration were close to identity. The combination of the host monitor with the remodelled flow sensor allowed accurate in vitro measurement of flows and volumes in a range expected during large animal anaesthesia. This combination has potential as a reliable spirometric monitor for use during large animal anaesthesia.

  20. Liquid-metal pin-fin pressure drop by correlation in cross flow

    International Nuclear Information System (INIS)

    Wang, Zhibi; Kuzay, T.M.; Assoufid, L.

    1994-01-01

    The pin-fin configuration is widely used as a heat transfer enhancement method in high-heat-flux applications. Recently, the pin-fin design with liquid-metal coolant was also applied to synchrotron-radiation beamline devices. This paper investigates the pressure drop in a pin-post design beamline mirror with liquid gallium as the coolant. Because the pin-post configuration is a relatively new concept, information in literature about pin-post mirrors or crystals is rare, and information about the pressure drop in pin-post mirrors with liquid metal as the coolant is even more sparse. Due to this the authors considered the cross flow in cylinder-array geometry, which is very similar to that of the pin-post, to examine the pressure drop correlation with liquid metals over pin fins. The cross flow of fluid with various fluid characteristics or properties through a tube bank was studied so that the results can be scaled to the pin-fin geometry with liquid metal as the coolant. Study lead to two major variables to influence the pressure drop: fluid properties, viscosity and density, and the relative length of the posts. Correlation of the pressure drop between long and short posts and the prediction of the pressure drop of liquid metal in the pin-post mirror and comparison with an existing experiment are addressed

  1. Integrated Cantilever-Based Flow Sensors with Tunable Sensitivity for In-Line Monitoring of Flow Fluctuations in Microfluidic Systems

    Directory of Open Access Journals (Sweden)

    Nadine Noeth

    2013-12-01

    Full Text Available For devices such as bio-/chemical sensors in microfluidic systems, flow fluctuations result in noise in the sensor output. Here, we demonstrate in-line monitoring of flow fluctuations with a cantilever-like sensor integrated in a microfluidic channel. The cantilevers are fabricated in different materials (SU-8 and SiN and with different thicknesses. The integration of arrays of holes with different hole size and number of holes allows the modification of device sensitivity, theoretical detection limit and measurement range. For an average flow in the microliter range, the cantilever deflection is directly proportional to the flow rate fluctuations in the microfluidic channel. The SiN cantilevers show a detection limit below 1 nL/min and the thinnest SU-8 cantilevers a detection limit below 5 nL/min. Finally, the sensor is applied for in-line monitoring of flow fluctuations generated by external pumps connected to the microfluidic system.

  2. Negative-Pressure Hydrocephalus: A Case Report on Successful Treatment Under Intracranial Pressure Monitoring with Bilateral Ventriculoperitoneal Shunts.

    Science.gov (United States)

    Pandey, Sajan; Jin, Yi; Gao, Liang; Zhou, Cheng Cheng; Cui, Da Ming

    2017-03-01

    Negative-pressure hydrocephalus (NegPH), a very rare condition of unknown etiology and optimal treatment, usually presents postneurosurgery with clinical and imaging features of hydrocephalus, but with negative cerebrospinal fluid pressure. We describe a NegPH case of -3 mm Hg intracranial pressure that was successfully treated to achieve 5 mm Hg under continuous intracranial pressure monitoring with horizontal positioning, head down and legs elevated to 10°-15°, neck wrapping for controlled venous drainage, chest and abdomen bandages, infusion of 5% dextrose fluid to lower plasma osmolarity (Na + , 130-135 mmol/L), daily cerebrospinal fluid drainage >200 mL, and arterial blood gas partial pressure of carbon dioxide >40 mm Hg. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Non-invasive assessment of pulsatile intracranial pressure with phase-contrast magnetic resonance imaging.

    Directory of Open Access Journals (Sweden)

    Geir Ringstad

    Full Text Available Invasive monitoring of pulsatile intracranial pressure can accurately predict shunt response in patients with idiopathic normal pressure hydrocephalus, but may potentially cause complications such as bleeding and infection. We tested how a proposed surrogate parameter for pulsatile intracranial pressure, the phase-contrast magnetic resonance imaging derived pulse pressure gradient, compared with its invasive counterpart. In 22 patients with suspected idiopathic normal pressure hydrocephalus, preceding invasive intracranial pressure monitoring, and any surgical shunt procedure, we calculated the pulse pressure gradient from phase-contrast magnetic resonance imaging derived cerebrospinal fluid flow velocities obtained at the upper cervical spinal canal using a simplified Navier-Stokes equation. Repeated measurements of the pulse pressure gradient were also undertaken in four healthy controls. Of 17 shunted patients, 16 responded, indicating high proportion of "true" normal pressure hydrocephalus in the patient cohort. However, there was no correlation between the magnetic resonance imaging derived pulse pressure gradient and pulsatile intracranial pressure (R = -.18, P = .43. Pulse pressure gradients were also similar in patients and healthy controls (P = .26, and did not differ between individuals with pulsatile intracranial pressure above or below established thresholds for shunt treatment (P = .97. Assessment of pulse pressure gradient at level C2 was therefore not found feasible to replace invasive monitoring of pulsatile intracranial pressure in selection of patients with idiopathic normal pressure hydrocephalus for surgical shunting. Unlike invasive, overnight monitoring, the pulse pressure gradient from magnetic resonance imaging comprises short-term pressure fluctuations only. Moreover, complexity of cervical cerebrospinal fluid flow and -pulsatility at the upper cervical spinal canal may render the pulse pressure gradient a poor surrogate

  4. Prediction of the relationship between flow of tubular pump and differential pressure within inlet passage with CFD method

    International Nuclear Information System (INIS)

    Yu, Y H; Cheng, B

    2012-01-01

    The measurement of flow of tubular pump, in which the differential pressure of two measuring points within inlet passage is replaced by the mean differential pressure of two specified section of inlet passage to calibrate the relationship between flow and differential pressure, is developed. The numerical simulation on differential pressure of two measuring points within inlet passage, which is started before the pump set test, is carried out with the standard k-ε turbulence model and SIMPLEC algorithm. The comparison of the relationships between flow and differential pressure fitted respectively with the data from numerical simulation and pump set test shows that the calibration accuracy about two different sources of data is nearly same. The conclusion can be drawn that the calibration of the relationship between flow and differential pressure with CFD is feasible. The CFD-based flow measurement method, as a more simple and convenient way, can be applied in tubular pumps.

  5. Novel design for transparent high-pressure fuel injector nozzles

    Science.gov (United States)

    Falgout, Z.; Linne, M.

    2016-08-01

    The efficiency and emissions of internal combustion (IC) engines are closely tied to the formation of the combustible air-fuel mixture. Direct-injection engines have become more common due to their increased practical flexibility and efficiency, and sprays dominate mixture formation in these engines. Spray formation, or rather the transition from a cylindrical liquid jet to a field of isolated droplets, is not completely understood. However, it is known that nozzle orifice flow and cavitation have an important effect on the formation of fuel injector sprays, even if the exact details of this effect remain unknown. A number of studies in recent years have used injectors with optically transparent nozzles (OTN) to allow observation of the nozzle orifice flow. Our goal in this work is to design various OTN concepts that mimic the flow inside commercial injector nozzles, at realistic fuel pressures, and yet still allow access to the very near nozzle region of the spray so that interior flow structure can be correlated with primary breakup dynamics. This goal has not been achieved until now because interior structures can be very complex, and the most appropriate optical materials are brittle and easily fractured by realistic fuel pressures. An OTN design that achieves realistic injection pressures and grants visual access to the interior flow and spray formation will be explained in detail. The design uses an acrylic nozzle, which is ideal for imaging the interior flow. This nozzle is supported from the outside with sapphire clamps, which reduces tensile stresses in the nozzle and increases the nozzle's injection pressure capacity. An ensemble of nozzles were mechanically tested to prove this design concept.

  6. Results of monitoring at Olkiluoto in 2009. Hydrology

    International Nuclear Information System (INIS)

    Vaittinen, T.; Ahokas, H.; Klockars, J.; Nummela, J.; Pentti, E.; Penttinen, T.; Tammisto, E.; Karvonen, T.; Lindgren, S.

    2010-08-01

    The impact of the ONKALO construction is monitored by measuring and observing numerous different parameters of hydrology, geochemistry, environment, rock mechanics and foreign materials. The Hydrological Monitoring Programme consists of the following parameters: groundwater level, hydraulic head, flow conditions in open boreholes, cross drillhole flow, hydraulic conductivity, groundwater salinity (in situ EC), precipitation (including snow), sea-water level, surface flow (runoff), infiltration, ground frost, leakages in tunnels, water balance in the tunnel system and in Korvensuo Reservoir. This Report focuses on hydrogeological parameters. Other parameters, like precipitation, ground frost etc. will be reported in the Environment Report. Mainly the monitoring has been carried out according to plan. This Report presents the results for the year 2009. A significant change in the Monitoring Programme was performed while most of the open drillholes were packed-off before excavation of the ONKALO access tunnel through the hydrogeological HZ20 zones began in Jun 2008. Prior to packing-off, open drillholes connected the main hydrogeological features, HZ19 and HZ20 systems, to each other. Due to packing-off open drillholes, number of flow logging and hydraulic testing monitoring measurements has considerably decreased. The observed changes in groundwater level in shallow observation tubes in the overburden and in shallow drillholes in the bedrock are not necessarily caused by the construction of ONKALO. However, weak indications of decrease in groundwater level have been observed. The effects on head deeper in the bedrock have been both shortterm and long-term and in 2009 these were mostly connected to drilling of grouting holes of the shafts trough the HZ20 zones. In other drillholes except packed-off sections connected to the HZ20 system, long-term changes i.e. decrease in pressure heads near ONKALO have remained on the same order of magnitude, c 1 m, as the year before

  7. Supersonic flow over a pitching delta wing using surface pressure measurements and numerical simulations

    Directory of Open Access Journals (Sweden)

    Mostafa HADIDOOLABI

    2018-01-01

    Full Text Available Experimental and numerical methods were applied to investigating high subsonic and supersonic flows over a 60° swept delta wing in fixed state and pitching oscillation. Static pressure coefficient distributions over the wing leeward surface and the hysteresis loops of pressure coefficient versus angle of attack at the sensor locations were obtained by wind tunnel tests. Similar results were obtained by numerical simulations which agreed well with the experiments. Flow structure around the wing was also demonstrated by the numerical simulation. Effects of Mach number and angle of attack on pressure distribution curves in static tests were investigated. Effects of various oscillation parameters including Mach number, mean angle of attack, pitching amplitude and frequency on hysteresis loops were investigated in dynamic tests and the associated physical mechanisms were discussed. Vortex breakdown phenomenon over the wing was identified at high angles of attack using the pressure coefficient curves and hysteresis loops, and its effects on the flow features were discussed.

  8. CFD analysis of multiphase coolant flow through fuel rod bundles in advanced pressure tube nuclear reactors

    International Nuclear Information System (INIS)

    Catana, A.; Turcu, I.; Prisecaru, I.; Dupleac, D.; Danila, N.

    2010-01-01

    The key component of a pressure tube nuclear reactor core is pressure tube filled with a stream of fuel bundles. This feature makes them suitable for CFD thermal-hydraulic analysis. A methodology for CFD analysis applied to pressure tube nuclear reactors is presented in this paper, which is focused on advanced pressure tube nuclear reactors. The complex flow conditions inside pressure tube are analysed by using the Eulerian multiphase model implemented in FLUENT CFD computer code. Fuel rods in these channels are superheated but the liquid is under high pressure, so it is sub-cooled in normal operating conditions on most of pressure tube length. In the second half of pressure tube length, the onset of boiling occurs, so the flow consists of a gas liquid mixture, with the volume of gas increasing along the length of the channel in the direction of the flow. Limited computer resources enforced us to use CFD analysis for segments of pressure tube. Significant local geometries (junctions, spacers) were simulated. Main results of this work are: prediction of main thermal-hydraulic parameters along pressure tube including CHF evaluation through fuel assemblies. (authors)

  9. NDE and Stress Monitoring on Composite Overwrapped Pressure Vessels, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Damage caused by composite overwrapped pressure vessels (COPVs) failure can be catastrophic. Thus, monitoring condition and stress in the composite overwrap,...

  10. Frictional pressure drop of high pressure steam-water two-phase flow in internally helical ribbed tubes

    International Nuclear Information System (INIS)

    Tingkuan, C.; Xuanzheng, C.

    1987-01-01

    It is well known that the internally helical ribbed tubes are effective in suppressing the dry-out in boiling tubes at high pressures, so they are widely used as furnace water wall tubes in modern large steam power boilers. Design of the boilers requires the data on frictional pressure drop characteristics of the ribbed tubes, but they are not sufficient now. This paper describes the experimental results on the adiabatic frictional pressure drop in both horizontal ribbed tubes with measured mean inside diameter of 11.69 mm and 35.42 mm at high pressure from 10 to 21 MPa, mass flow rate from 350 to 3800 kg/m/sup 2/s and steam quality from 0 to 1 in our high pressure electrically heated water loop. Simultaneously, both smooth tubes under the same conditions for comparison. Based on the tests the correlation for determining the frictional pressure drop of internally ribbed tubes are proposed

  11. Evolution from electrophysiologic to hemodynamic monitoring: the story of left atrial and pulmonary artery pressure monitors

    Directory of Open Access Journals (Sweden)

    Deirdre M Mooney

    2015-10-01

    Full Text Available Heart failure (HF is a costly, challenging and highly prevalent medical condition. Hospitalization for acute decompensation is associated with high morbidity and mortality. Despite application of evidence-based medical therapies and technologies, HF remains a formidable challenge for virtually all healthcare systems. Repeat hospitalizations for acute decompensated HF (ADHF can have major financial impact on institutions and resources. Early and accurate identification of impending ADHF is of paramount importance yet there is limited high quality evidence or infrastructure to guide management in the outpatient setting. Historically, ADHF was identified by physical exam findings or invasive hemodynamic monitoring during a hospital admission; however, advances in medical microelectronics and the advent of device-based diagnostics have enabled long-term ambulatory monitoring of HF patients in the outpatient setting. These monitors have evolved from piggybacking on cardiac implantable electrophysiologic devices to standalone implantable hemodynamic monitors that transduce left atrial or pulmonary artery pressures as surrogate measures of left ventricular filling pressure. As technology evolves, devices will likely continue to miniaturize while their capabilities grow. An important, persistent challenge that remains is developing systems to translate the large volumes of real-time data, particularly data trends, into actionable information that leads to appropriate, safe and timely interventions without overwhelming outpatient cardiology and general medical practices. Future directions for implantable hemodynamic monitors beyond their utility in heart failure may include management of other major chronic diseases such as pulmonary hypertension, end stage renal disease and portal hypertension.

  12. Evolution from electrophysiologic to hemodynamic monitoring: the story of left atrial and pulmonary artery pressure monitors.

    Science.gov (United States)

    Mooney, Deirdre M; Fung, Erik; Doshi, Rahul N; Shavelle, David M

    2015-01-01

    Heart failure (HF) is a costly, challenging and highly prevalent medical condition. Hospitalization for acute decompensation is associated with high morbidity and mortality. Despite application of evidence-based medical therapies and technologies, HF remains a formidable challenge for virtually all healthcare systems. Repeat hospitalizations for acute decompensated HF (ADHF) can have major financial impact on institutions and resources. Early and accurate identification of impending ADHF is of paramount importance yet there is limited high quality evidence or infrastructure to guide management in the outpatient setting. Historically, ADHF was identified by physical exam findings or invasive hemodynamic monitoring during a hospital admission; however, advances in medical microelectronics and the advent of device-based diagnostics have enabled long-term ambulatory monitoring of HF patients in the outpatient setting. These monitors have evolved from piggybacking on cardiac implantable electrophysiologic devices to standalone implantable hemodynamic monitors that transduce left atrial or pulmonary artery pressures as surrogate measures of left ventricular filling pressure. As technology evolves, devices will likely continue to miniaturize while their capabilities grow. An important, persistent challenge that remains is developing systems to translate the large volumes of real-time data, particularly data trends, into actionable information that leads to appropriate, safe and timely interventions without overwhelming outpatient cardiology and general medical practices. Future directions for implantable hemodynamic monitors beyond their utility in heart failure may include management of other major chronic diseases such as pulmonary hypertension, end stage renal disease and portal hypertension.

  13. Shock tunnel measurements of surface pressures in shock induced separated flow field using MEMS sensor array

    International Nuclear Information System (INIS)

    Sriram, R; Jagadeesh, G; Ram, S N; Hegde, G M; Nayak, M M

    2015-01-01

    Characterized not just by high Mach numbers, but also high flow total enthalpies—often accompanied by dissociation and ionization of flowing gas itself—the experimental simulation of hypersonic flows requires impulse facilities like shock tunnels. However, shock tunnel simulation imposes challenges and restrictions on the flow diagnostics, not just because of the possible extreme flow conditions, but also the short run times—typically around 1 ms. The development, calibration and application of fast response MEMS sensors for surface pressure measurements in IISc hypersonic shock tunnel HST-2, with a typical test time of 600 μs, for the complex flow field of strong (impinging) shock boundary layer interaction with separation close to the leading edge, is delineated in this paper. For Mach numbers 5.96 (total enthalpy 1.3 MJ kg −1 ) and 8.67 (total enthalpy 1.6 MJ kg −1 ), surface pressures ranging from around 200 Pa to 50 000 Pa, in various regions of the flow field, are measured using the MEMS sensors. The measurements are found to compare well with the measurements using commercial sensors. It was possible to resolve important regions of the flow field involving significant spatial gradients of pressure, with a resolution of 5 data points within 12 mm in each MEMS array, which cannot be achieved with the other commercial sensors. In particular, MEMS sensors enabled the measurement of separation pressure (at Mach 8.67) near the leading edge and the sharply varying pressure in the reattachment zone. (paper)

  14. Flow Glottogram and Subglottal Pressure Relationship in Singers and Untrained Voices.

    Science.gov (United States)

    Sundberg, Johan

    2018-01-01

    This article combines results from three earlier investigations of the glottal voice source during phonation at varying degrees of vocal loudness (1) in five classically trained baritone singers (Sundberg et al., 1999), (2) in 15 female and 14 male untrained voices (Sundberg et al., 2005), and (3) in voices rated as hyperfunctional by an expert panel (Millgård et al., 2015). Voice source data were obtained by inverse filtering. Associated subglottal pressures were estimated from oral pressure during the occlusion for the consonant /p/. Five flow glottogram parameters, (1) maximum flow declination rate (MFDR), (2) peak-to-peak pulse amplitude, (3) level difference between the first and the second harmonics of the voice source, (4) closed quotient, and (5) normalized amplitude quotient, were averaged across the singer subjects and related to associated MFDR values. Strong, quantitative relations, expressed as equations, are found between subglottal pressure and MFDR and between MFDR and each of the other flow glottogram parameters. The values for the untrained voices, as well as those for the voices rated as hyperfunctional, deviate systematically from the values derived from the equations. Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  15. Laser Doppler flowmetry for bone blood flow measurement: correlation with microsphere estimates and evaluation of the effect of intracapsular pressure on femoral head blood flow

    International Nuclear Information System (INIS)

    Swiontkowski, M.F.; Tepic, S.; Perren, S.M.; Moor, R.; Ganz, R.; Rahn, B.A.

    1986-01-01

    Laser Doppler flowmetry (LDF) was used to measure bone blood flow in the rabbit femoral condyles. To correlate the LDF output signal blood cell flux to in vivo blood flow, simultaneous measurements using LDF and 85 Sr-labeled microspheres were made in an adult rabbit model. There was no correlation between the two methods for blood flow in the femoral condyles and the correlation between the two methods for blood flow in the femoral head does not achieve statistical significance. An LDF signal of 0.4 V was approximately equal to a microsphere measured flow rate of 0.4 ml blood/g bone/min. The strength of the correlation in the latter case may have been affected by (a) large arteriovenous shunts, (b) inadequate mixing of the microspheres with a left ventricular injection, and (c) insufficient numbers of microspheres present in the bone samples. When LDF was used to evaluate the effect of elevated intracapsular pressure on femoral head blood flow in skeletally mature rabbits, femoral head subchondral bone blood flow declined with increasing intracapsular pressure from a baseline value of 0.343 +/- 0.036 to a value of 0.127 +/- 0.27 at 120 cm of water pressure. The decline in femoral head blood flow was statistically significant at pressures of 40 cm of water or higher (p less than 0.001), and evaluation of sections of the proximal femora made from preterminal disulphine blue injections confirmed these findings. Intracapsular tamponade has an adverse effect on femoral head blood flow beginning well below central venous pressure and should be considered in the pathophysiology of posttraumatic and nontraumatic necrosis of the femoral head. Laser Doppler flowmetry was easy to use and appears to be a reproducible technique for evaluating femoral head blood flow, offering distinct advantages over the microsphere technique for measuring bone blood flow

  16. Techniques for Non-Invasive Monitoring of Arterial Blood Pressure

    Directory of Open Access Journals (Sweden)

    Agnes S. Meidert

    2018-01-01

    Full Text Available Since both, hypotension and hypertension, can potentially impair the function of vital organs such as heart, brain, or kidneys, monitoring of arterial blood pressure (BP is a mainstay of hemodynamic monitoring in acutely or critically ill patients. Arterial BP can either be obtained invasively via an arterial catheter or non-invasively. Non-invasive BP measurement provides either intermittent or continuous readings. Most commonly, an occluding upper arm cuff is used for intermittent non-invasive monitoring. BP values are then obtained either manually (by auscultation of Korotkoff sounds or palpation or automatically (e.g., by oscillometry. For continuous non-invasive BP monitoring, the volume clamp method or arterial applanation tonometry can be used. Both techniques enable the arterial waveform and BP values to be obtained continuously. This article describes the different techniques for non-invasive BP measurement, their advantages and limitations, and their clinical applicability.

  17. Implantable Biosensors for Real-time Strain and Pressure Monitoring

    Directory of Open Access Journals (Sweden)

    Keat Ghee Ong

    2008-10-01

    Full Text Available Implantable biosensors were developed for real-time monitoring of pressure and strain in the human body. The sensors, which are wireless and passive, consisted of a soft magnetic material and a permanent magnet. When exposed to a low frequency AC magnetic field, the soft magnetic material generated secondary magnetic fields that also included the higher-order harmonic modes. Parameters of interest were determined by measuring the changes in the pattern of these higher-order harmonic fields, which was achieved by changing the intensity of a DC magnetic field generated by a permanent magnet. The DC magnetic field, or the biasing field, was altered by changing the separation distance between the soft magnetic material and the permanent magnet. For pressure monitoring, the permanent magnet was placed on the membrane of an airtight chamber. Changes in the ambient pressure deflected the membrane, altering the separation distance between the two magnetic elements and thus the higher-order harmonic fields. Similarly, the soft magnetic material and the permanent magnet were separated by a flexible substrate in the stress/strain sensor. Compressive and tensile forces flexed the substrate, changing the separation distance between the two elements and the higher-order harmonic fields. In the current study, both stress/strain and pressure sensors were fabricated and characterized. Good stability, linearity and repeatability of the sensors were demonstrated. This passive and wireless sensor technology may be useful for long term detection of physical quantities within the human body as a part of treatment assessment, disease diagnosis, or detection of biomedical implant failures.

  18. Effect of Water Cut on Pressure Drop of Oil (D130) -Water Flow in 4″Horizontal Pipe

    Science.gov (United States)

    Basha, Mehaboob; Shaahid, S. M.; Al-Hems, Luai M.

    2018-03-01

    The oil-water flow in pipes is a challenging subject that is rich in physics and practical applications. It is often encountered in many oil and chemical industries. The pressure gradient of two phase flow is still subject of immense research. The present study reports pressure measurements of oil (D130)-water flow in a horizontal 4″ diameter stainless steel pipe at different flow conditions. Experiments were carried out for different water cuts (WC); 0-100%. Inlet oil-water flow rates were varied from 4000 to 8000 barrels-per-day in steps of 2000. It has been found that the frictional pressure drop decreases for WC = 0 - 40 %. With further increase in WC, friction pressure drop increases, this could be due to phase inversion.

  19. RFID-Based Monitoring And Access Control System For Parliamentary Campus

    Directory of Open Access Journals (Sweden)

    Sai Thu Rein Htun

    2015-08-01

    Full Text Available This paper is to implement monitoring and access control system based on RFID and Zigbee technology which can be used at Parliamentary Campus. Nowadays RFID technology is widely used for access control system because it is cheap waterproof and easy to use as well as it contains unique EPC electronic protect code .In addition Zigbee wireless module is cost-effective and can be reliable for security. Sothis system consists of RFID tag RFID reader Arduino Uno and Zigbee. This system can also be used for industrial amp commercial and security HVAC closures. This paper describes the results of point-to-point connection and point-to-multipoint connection using Zigbee and RFID technology.

  20. Long-term hydrothermal temperature and pressure monitoring equipped with a Kuroko cultivation apparatus on the deep-sea artificial hydrothermal vent at the middle Okinawa Trough

    Science.gov (United States)

    Masaki, Y.; Nozaki, T.; Saruhashi, T.; Kyo, M.; Sakurai, N.; Yokoyama, T.; Akiyama, K.; Watanabe, M.; Kumagai, H.; Maeda, L.; Kinoshita, M.

    2017-12-01

    The middle Okinawa Trough, located along the Ryukyu- arc on the margin of the East China Sea, has several active hydrothermal fields. From February to March 2016, Cruise CK16-01 by D/V Chikyu targeted the Iheya-North Knoll and southern flank of the Iheya Minor Ridge to comprehend sub-seafloor geological structure and polymetallic sulfide mineralization. In this cruise, we installed two Kuroko cultivation apparatuses equipped with P/T sensors, flowmeter and load cell to monitor pressure, temperature and flow rate of hydrothermal fluid discharged from the artificial hydrothermal vent together with weight of hydrothermal precipitate. During Cruise KR16-17 in January 2017, two cultivation cells with sensor loggers were successfully recovered by ROV Kaiko MK-IV and R/V Kairei. We report these physical sensor data obtained by more than 10 months monitoring at two deep-sea artificial hydrothermal vents through many first and challenging operations.Hole C9017B at southern flank of the Iheya Minor Ridge (water depth of 1,500 mbsl), fluid temperature was constant ca. 75 ºC for 5 months from the beginning of monitoring. Then temperature gradually decrease to be 40 ºC. In November 2016, temperature and pressure suddenly dropped and quickly recovered due to the disturbance of subseafloor hydrology, induced by another drilling operation at Hole C9017A which is 10.8 meters northeastward from Hole C9017B during Cruise CK16-05. Temperature data exhibit conspicuous periodic 12.4hour cycles and this is attributable to oceanic tidal response. The amplitude of temperature variations increased along with decline of the temperature variations increased along with decline of the temperature. The average flow rate was 67 L/min for 9 hours from the onset of monitoring.Hole C9024A at the Iheya-North Knoll (water depth of 1,050 msl), the maximum temperature reached 308 ºC, which is similar to the maximum value of 311 ºC obtained from the ROV thermometer. The average flow rate was 289 L

  1. Low cost self-made pressure distribution sensors for ergonomic chair: Are they suitable for posture monitoring?

    Science.gov (United States)

    Martinaitis, Arnas; Daunoraviciene, Kristina

    2018-05-18

    Long sitting causes many health problems for people. Healthy sitting monitoring systems, like real-time pressure distribution measuring, is in high demand and many methods of posture recognition were developed. Such systems are usually expensive and hardly available for the regular user. The aim of study is to develop low cost but sensitive enough pressure sensors and posture monitoring system. New self-made pressure sensors have been developed and tested, and prototype of pressure distribution measuring system was designed. Sensors measured at average noise amplitude of a = 56 mV (1.12%), average variation in sequential measurements of the same sensor s = 17 mV (0.34%). Signal variability between sensors averaged at 100 mV (2.0%). Weight to signal dependency graph was measured and hysteresis calculated. Results suggested the use of total sixteen sensors for posture monitoring system with accuracy of sensor sensitivity and repeatability are acceptable for posture monitoring, and it is possible to build low cost pressure distribution measurement system with graphical visualization without expensive equipment or complicated software.

  2. Valveless pumping mechanics of the embryonic heart during cardiac looping: Pressure and flow through micro-PIV.

    Science.gov (United States)

    Bark, D L; Johnson, B; Garrity, D; Dasi, L P

    2017-01-04

    Cardiovascular development is influenced by the flow-induced stress environment originating from cardiac biomechanics. To characterize the stress environment, it is necessary to quantify flow and pressure. Here, we quantify the flow field in a developing zebrafish heart during the looping stage through micro-particle imaging velocimetry and by analyzing spatiotemporal plots. We further build upon previous methods to noninvasively quantify the pressure field at a low Reynolds number using flow field data for the first time, while also comparing the impact of viscosity models. Through this method, we show that the atrium builds up pressure to ~0.25mmHg relative to the ventricle during atrial systole and that atrial expansion creates a pressure difference of ~0.15mmHg across the atrium, resulting in efficient cardiac pumping. With these techniques, it is possible to noninvasively fully characterize hemodynamics during heart development. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Interactive water monitoring system accessible by cordless telephone

    Science.gov (United States)

    Volpicelli, Richard; Andeweg, Pierre; Hagar, William G.

    1985-12-01

    A battery-operated, microcomputer-controlled monitoring device linked with a cordless telephone has been developed for remote measurements. This environmental sensor is self-contained and collects and processes data according to the information sent to its on-board computer system. An RCA model 1805 microprocessor forms the basic controller with a program encoded in memory for data acquisition and analysis. Signals from analog sensing devices used to monitor the environment are converted into digital signals and stored in random access memory of the microcomputer. This remote sensing system is linked to the laboratory by means of a cordless telephone whose base unit is connected to regular telephone lines. This offshore sensing system is simply accessed by a phone call originating from a computer terminal in the laboratory. Data acquisition is initiated upon request: Information continues to be processed and stored until the computer is reprogrammed by another phone call request. Information obtained may be recalled by a phone call after the desired environmental measurements are finished or while they are in progress. Data sampling parameters may be reset at any time, including in the middle of a measurement cycle. The range of the system is limited only by existing telephone grid systems and by the transmission characteristics of the cordless phone used as a communications link. This use of a cordless telephone, coupled with the on-board computer system, may be applied to other field studies requiring data transfer between an on-site analytical system and the laboratory.

  4. Role of Ambulatory and Home Blood Pressure Monitoring in Clinical Practice: A Narrative Review

    Science.gov (United States)

    Shimbo, Daichi; Abdalla, Marwah; Falzon, Louise; Townsend, Raymond R.; Muntner, Paul

    2015-01-01

    Hypertension, a common cardiovascular disease (CVD) risk factor, is usually diagnosed and treated based on blood pressure readings obtained in the clinic setting. Blood pressure may differ considerably when measured in the clinic versus outside of the clinic setting. Over the past several decades, evidence has accumulated on two approaches for measuring out-of-clinic blood pressure: ambulatory blood pressure monitoring (ABPM) and home blood pressure monitoring (HBPM). Blood pressure measures on ABPM and HBPM each have a stronger association with CVD outcomes than clinic blood pressure. Controversy exists whether ABPM or HBPM is superior for estimating CVD risk, and under what circumstances these methods should be used in clinical practice for assessing out-of-clinic blood pressure. This review describes ABPM and HBPM procedures, the blood pressure phenotypic measures that can be ascertained, and the evidence that supports the use of each approach to measure out-of-clinic blood pressure. This review also describes barriers to the successful implementation of ABPM and HBPM in clinical practice, proposes core competencies for the conduct of these procedures, and highlights important areas for future research. PMID:26457954

  5. Patient Blood Pressure and Pulse Rate Monitoring With an Alert ...

    African Journals Online (AJOL)

    2012-12-01

    Dec 1, 2012 ... an Alert System Using the Omron 790it Blood Pressure. Monitor ... detailed medical information on the vital signs of patients and will save many lives that may be lost. Keywords: Omron .... at rest, in beats per minute (BPM):.

  6. Development of a setup to enable stable and accurate flow conditions for membrane biofouling studies

    KAUST Repository

    Bucs, Szilard

    2015-07-10

    Systematic laboratory studies on membrane biofouling require experimental conditions that are well defined and representative for practice. Hydrodynamics and flow rate variations affect biofilm formation, morphology, and detachment and impacts on membrane performance parameters such as feed channel pressure drop. There is a suite of available monitors to study biofouling, but systems to operate monitors have not been well designed to achieve an accurate, constant water flow required for a reliable determination of biomass accumulation and feed channel pressure drop increase. Studies were done with membrane fouling simulators operated in parallel with manual and automated flow control, with and without dosage of a biodegradable substrate to the feedwater to enhance biofouling rate. High flow rate variations were observed for the manual water flow system (up to ≈9%) compared to the automatic flow control system (<1%). The flow rate variation in the manual system was strongly increased by biofilm accumulation, while the automatic system maintained an accurate and constant water flow in the monitor. The flow rate influences the biofilm accumulation and the impact of accumulated biofilm on membrane performance. The effect of the same amount of accumulated biomass on the pressure drop increase was related to the linear flow velocity. Stable and accurate feedwater flow rates are essential for biofouling studies in well-defined conditions in membrane systems. © 2015 Balaban Desalination Publications. All rights reserved.

  7. Characterizing developing adverse pressure gradient flows subject to surface roughness

    Science.gov (United States)

    Brzek, Brian; Chao, Donald; Turan, Özden; Castillo, Luciano

    2010-04-01

    An experimental study was conducted to examine the effects of surface roughness and adverse pressure gradient (APG) on the development of a turbulent boundary layer. Hot-wire anemometry measurements were carried out using single and X-wire probes in all regions of a developing APG flow in an open return wind tunnel test section. The same experimental conditions (i.e., T ∞, U ref, and C p) were maintained for smooth, k + = 0, and rough, k + = 41-60, surfaces with Reynolds number based on momentum thickness, 3,000 carefully designed such that the x-dependence in the flow field was known. Despite this fact, only a very small region of the boundary layer showed a balance of the various terms in the integrated boundary layer equation. The skin friction computed from this technique showed up to a 58% increase due to the surface roughness. Various equilibrium parameters were studied and the effect of roughness was investigated. The generated flow was not in equilibrium according to the Clauser (J Aero Sci 21:91-108, 1954) definition due to its developing nature. After a development region, the flow reached the equilibrium condition as defined by Castillo and George (2001), where Λ = const, is the pressure gradient parameter. Moreover, it was found that this equilibrium condition can be used to classify developing APG flows. Furthermore, the Zagarola and Smits (J Fluid Mech 373:33-79, 1998a) scaling of the mean velocity deficit, U ∞δ*/δ, can also be used as a criteria to classify developing APG flows which supports the equilibrium condition of Castillo and George (2001). With this information a ‘full APG region’ was defined.

  8. Hemodynamic monitoring in the critically ill.

    Science.gov (United States)

    Voga, G

    1995-06-01

    Monitoring of vital functions is one of the most important and essential tools in the management of critically ill patients in the ICU. Today it is possible to detect and analyze a great variety of physiological signals by various noninvasive and invasive techniques. An intensivist should be able to select and perform the most appropriate monitoring method for the individual patient considering risk-benefit ratio of the particular monitoring technique and the need for immediate therapy, specific diagnosis, continuous monitoring and evaluation of morphology should be included. Despite rapid development of noninvasive monitoring techniques, invasive hemodynamic monitoring in still one of the most basic ICU procedures. It enables monitoring of pressures, flow and saturation, pressures in the systemic and pulmonary circulation, estimation of cardiac performance and judgment of the adequacy of the cardiocirculatory system. Carefully and correctly obtained information are basis for proper hemodynamic assessment which usually effects the therapeutic decisions.

  9. Red blood cell (RBC) suspensions in confined microflows: Pressure-flow relationship.

    Science.gov (United States)

    Stauber, Hagit; Waisman, Dan; Korin, Netanel; Sznitman, Josué

    2017-10-01

    Microfluidic-based assays have become increasingly popular to explore microcirculation in vitro. In these experiments, blood is resuspended to a desired haematocrit level in a buffer solution, where frequent choices for preparing RBC suspensions comprise notably Dextran and physiological buffer. Yet, the rational for selecting one buffer versus another is often ill-defined and lacks detailed quantification, including ensuing changes in RBC flow characteristics. Here, we revisit RBC suspensions in microflows and attempt to quantify systematically some of the differences emanating between buffers. We measure bulk flow rate (Q) of RBC suspensions, using PBS- and Dextran-40, as a function of the applied pressure drop (ΔP) for two hematocrits (∼0% and 23%). Two distinct microfluidic designs of varying dimensions are employed: a straight channel larger than and a network array similar to the size of individual RBCs. Using the resulting pressure-flow curves, we extract the equivalent hydrodynamic resistances and estimate the relative viscosities. These efforts are a first step in rigorously quantifying the influence of the 'background' buffer on RBC flows within microfluidic devices and thereby underline the importance of purposefully selecting buffer suspensions for microfluidic in vitro assays. Copyright © 2017. Published by Elsevier Ltd.

  10. A chest drainage system with a real-time pressure monitoring device.

    Science.gov (United States)

    Chen, Chih-Hao; Liu, Tsang-Pai; Chang, Ho; Huang, Tung-Sung; Liu, Hung-Chang; Chen, Chao-Hung

    2015-07-01

    Tube thoracostomy is a common procedure. A chest bottle may be used to both collect fluids and monitor the recovery of the chest condition. The presence of the "tidaling phenomenon" in the bottle can be reflective of the extent of patient's recovery. However, current practice essentially depends on gross observation of the bottle. The device used here is designed for a real-time monitoring of change in pleural pressure to allow clinicians to objectively determine when the lung has recovered, which is crucially important in order to judge when to remove the chest tube. The device is made of a pressure sensor with an operating range between -100 to +100 cmH2O and an amplifying using the "Wheatstone bridge" concept. Recording and analysis was performed with LABview software. The data can be shown in real-time on screen and also be checked retrospectively. The device was connected to the second part of a three-bottle drain system by a three-way connector. The test animals were two 40-kg pigs. We used a thoracoscopic procedure to create an artificial lung laceration with endoscopic scissors. Active air leaks could result in vigorous tidaling phenomenon up to 20 cmH2O. In the absence of gross tidaling phenomenon, the pressure changes were around 0.25 cmH2O. This real-time pleural pressure monitoring device can help clinicians objectively judge the extent of recovery of the chest condition. It can be used as an effective adjunct with the current chest drain system.

  11. NMR reaction monitoring in flow synthesis.

    Science.gov (United States)

    Gomez, M Victoria; de la Hoz, Antonio

    2017-01-01

    Recent advances in the use of flow chemistry with in-line and on-line analysis by NMR are presented. The use of macro- and microreactors, coupled with standard and custom made NMR probes involving microcoils, incorporated into high resolution and benchtop NMR instruments is reviewed. Some recent selected applications have been collected, including synthetic applications, the determination of the kinetic and thermodynamic parameters and reaction optimization, even in single experiments and on the μL scale. Finally, software that allows automatic reaction monitoring and optimization is discussed.

  12. Fluid flow measurements by means of vibration monitoring

    International Nuclear Information System (INIS)

    Campagna, Mauro M; Dinardo, Giuseppe; Fabbiano, Laura; Vacca, Gaetano

    2015-01-01

    The achievement of accurate fluid flow measurements is fundamental whenever the control and the monitoring of certain physical quantities governing an industrial process are required. In that case, non-intrusive devices are preferable, but these are often more sophisticated and expensive than those which are more common (such as nozzles, diaphrams, Coriolis flowmeters and so on). In this paper, a novel, non-intrusive, simple and inexpensive methodology is presented to measure the fluid flow rate (in a turbulent regime) whose physical principle is based on the acquisition of transversal vibrational signals induced by the fluid itself onto the pipe walls it is flowing through. Such a principle of operation would permit the use of micro-accelerometers capable of acquiring and transmitting the signals, even by means of wireless technology, to a control room for the monitoring of the process under control. A possible application (whose feasibility will be investigated by the authors in a further study) of this introduced technology is related to the employment of a net of micro-accelerometers to be installed on pipeline networks of aqueducts. This apparatus could lead to the faster and easier detection and location of possible leaks of fluid affecting the pipeline network with more affordable costs. The authors, who have previously proven the linear dependency of the acceleration harmonics amplitude on the flow rate, here discuss an experimental analysis of this functional relation with the variation in the physical properties of the pipe in terms of its diameter and constituent material, to find the eventual limits to the practical application of the measurement methodology. (paper)

  13. Fluid flow measurements by means of vibration monitoring

    Science.gov (United States)

    Campagna, Mauro M.; Dinardo, Giuseppe; Fabbiano, Laura; Vacca, Gaetano

    2015-11-01

    The achievement of accurate fluid flow measurements is fundamental whenever the control and the monitoring of certain physical quantities governing an industrial process are required. In that case, non-intrusive devices are preferable, but these are often more sophisticated and expensive than those which are more common (such as nozzles, diaphrams, Coriolis flowmeters and so on). In this paper, a novel, non-intrusive, simple and inexpensive methodology is presented to measure the fluid flow rate (in a turbulent regime) whose physical principle is based on the acquisition of transversal vibrational signals induced by the fluid itself onto the pipe walls it is flowing through. Such a principle of operation would permit the use of micro-accelerometers capable of acquiring and transmitting the signals, even by means of wireless technology, to a control room for the monitoring of the process under control. A possible application (whose feasibility will be investigated by the authors in a further study) of this introduced technology is related to the employment of a net of micro-accelerometers to be installed on pipeline networks of aqueducts. This apparatus could lead to the faster and easier detection and location of possible leaks of fluid affecting the pipeline network with more affordable costs. The authors, who have previously proven the linear dependency of the acceleration harmonics amplitude on the flow rate, here discuss an experimental analysis of this functional relation with the variation in the physical properties of the pipe in terms of its diameter and constituent material, to find the eventual limits to the practical application of the measurement methodology.

  14. Battery-Free Smart Sock for Abnormal Relative Plantar Pressure Monitoring.

    Science.gov (United States)

    Lin, Xiaoyou; Seet, Boon-Chong

    2017-04-01

    This paper presents a new design of a wearable plantar pressure monitoring system in the form of a smart sock for sensing abnormal relative pressure changes. One advantage of this approach is that with a battery-free design, this system can be powered solely by radio frequency (RF) energy harvested from a radio frequency identification (RFID) reader unit hosted on a smartphone of the wearer. At the same time, this RFID reader can read foot pressure values from an embedded sensor-tag in the sock. A pressure sensing matrix made of conductive fabric and flexible piezo-resistive material is integrated into the sock during the knitting process. Sensed foot pressures are digitized and stored in the memory of a sensor-tag, thus allowing relative foot pressure values to be tracked. The control unit of the smart sock is assembled on a flexible printed circuit board (FPC) that can be strapped to the lower limb and detached easily when it is not in use. Experiments show that the system can operate reliably in both tasks of RF energy harvesting and pressure measurement.

  15. Comparison of ambulatory blood pressure monitoring and office blood pressure measurements in obese children and adolescents.

    Science.gov (United States)

    Renda, Rahime

    2018-04-01

    Obesity in adults has been related to hypertension and abnormal nocturnal dipping of blood pressure, which are associated with poor cardiovascular and renal outcomes. Here, we aimed to resolve the relationship between the degree of obesity, the severity of hypertension and dipping status on ambulatory blood pressure in obese children. A total 72 patients with primary obesity aged 7 to 18 years (mean: 13.48 ± 3.25) were selected. Patients were divided into three groups based on body mass index (BMİ) Z-score. Diagnosis and staging of ambulatory hypertension based on 24-h blood pressure measurements, obtained from ambulatory blood pressure monitoring. Based on our ambulatory blood pressure data, 35 patients (48.6%) had hypertension, 7 (20%) had ambulatory prehypertension, 21 (60%) had hypertension, and 7 patients (20%) had severe ambulatory hypertension. There was a significant relationship between severity of hypertension and the degree of obesity (p lood pressure results and loads were similar between groups. Diastolic and mean arterial blood pressure levels during the night, diastolic blood pressure loads, and heart rate during the day were significantly higher in Group 3 (p lood pressure at night, mean arterial pressure at night, diastolic blood pressure loads and heart rate at day. Increase in BMI Z-score does not a significant impact on daytime blood pressure and nocturnal dipping status.

  16. A liquid crystal polymer membrane MEMS sensor for flow rate and flow direction sensing applications

    International Nuclear Information System (INIS)

    Kottapalli, A G P; Tan, C W; Olfatnia, M; Miao, J M; Barbastathis, G; Triantafyllou, M

    2011-01-01

    The paper reports the design, fabrication and experimental results of a liquid crystal polymer (LCP) membrane-based pressure sensor for flow rate and flow direction sensing applications. Elaborate experimental testing results demonstrating the sensors' performance as an airflow sensor have been illustrated and validated with theory. MEMS sensors using LCP as a membrane structural material show higher sensitivity and reliability over silicon counterparts. The developed device is highly robust for harsh environment applications such as atmospheric wind flow monitoring and underwater flow sensing. A simple, low-cost and repeatable fabrication scheme has been developed employing low temperatures. The main features of the sensor developed in this work are a LCP membrane with integrated thin film gold piezoresistors deposited on it. The sensor developed demonstrates a good sensitivity of 3.695 mV (ms −1 ) −1 , large operating range (0.1 to >10 ms −1 ) and good accuracy in measuring airflow with an average error of only 3.6% full-scale in comparison with theory. Various feasible applications of the developed sensor have been demonstrated with experimental results. The sensor was tested for two other applications—in clinical diagnosis for breath rate, breath velocity monitoring, and in underwater applications for object detection by sensing near-field spatial flow pressure

  17. Synchronous Surface Pressure and Velocity Measurements of standard model in hypersonic flow

    Directory of Open Access Journals (Sweden)

    Zhijun Sun

    2018-01-01

    Full Text Available Experiments in the Hypersonic Wind tunnel of NUAA(NHW present synchronous measurements of bow shockwave and surface pressure of a standard blunt rotary model (AGARD HB-2, which was carried out in order to measure the Mach-5-flow above a blunt body by PIV (Particle Image Velocimetry as well as unsteady pressure around the rotary body. Titanium dioxide (Al2O3 Nano particles were seeded into the flow by a tailor-made container. With meticulous care designed optical path, the laser was guided into the vacuum experimental section. The transient pressure was obtained around model by using fast-responding pressure-sensitive paint (PSPsprayed on the model. All the experimental facilities were controlled by Series Pulse Generator to ensure that the data was time related. The PIV measurements of velocities in front of the detached bow shock agreed very well with the calculated value, with less than 3% difference compared to Pitot-pressure recordings. The velocity gradient contour described in accord with the detached bow shock that showed on schlieren. The PSP results presented good agreement with the reference data from previous studies. Our work involving studies of synchronous shock-wave and pressure measurements proved to be encouraging.

  18. Two-phase flow and pressure drop in T-junctions with horizontal run and vertical branch

    International Nuclear Information System (INIS)

    Katsaounis, A.

    1987-01-01

    Visual observations of single- and two-phase dividing flow and pressure drop measurements were performed in T-junctions with horizontal run and vertical branch. Both tees used were geometrically similar, in a scale of 1:4. The measurements were performed for plug/slug and stratified flow pattern regime in horizontal tube. Based on the single-phase form-resistance pressure drop correlation of Gardel a corresponded calculation model was developed for the two-phase flow verified by the own measurements. (orig.) [de

  19. Pressure fluctuations induced by fluid flow in singular points of industrial circuits

    International Nuclear Information System (INIS)

    Gibert, R.J.; Villard, B.

    1977-01-01

    Flow singularities (enlargements, bards, valves, tees, ...) generate in the circuits of industrial plants wall pressure fluctuations which are the main cause of vibration. A methodical study of the most current singularities has been performed at C.E.A./D.E.M.T. On one hand a theory of noise generation by unsteady flow in internal acoustics has been developed. This theory uses the basic ideas initiated by LIGHTILL. As a result it is shown that the plane wave propagation is a valid assumption and that a singularity can be acoustically modelled by a pressure and a mass-flow-rate discontinuities. Both are random functions of time, the spectra of which are determined from the local fluctuations characteristics. On other hand, characteristics of several singularities have been measured: intercorrelation spectra of local pressure fluctuations. Autocorrelation spectra of associated acoustical sources (the measure of the acoustical pressures in the experimental circuit are interpreted by using the D.E.M.T. computer code VIBRAPHONE which gives the acoustical response of a complex circuit. Experimental atmospheric air and water loops have been used. The Reynolds number has been changed between about 10 5 and 10 6 ; the Mach number between about 0,01 and 0,5. Simple laws with dimensionless parameters are formulated and can be used for the estimation of the acoustical and mechanical vibration level of a circuit with given singularities

  20. Development of an Arm Phantom for Testing Non-Invasive Blood Pressure Monitors

    Science.gov (United States)

    Anderson-Jackson, LaTecia D.

    Approximately one in every three adults age 20 older are diagnosed with high blood pressure or hypertension. It is estimated that hypertension affects 78 million people in the United States, is equally prevalent in both men and woman (Crabtree, Stuart-Shor, & McAllister, 2013). In the United States, around 78% of people suffering from hypertension are aware of their condition, with only 68% using hypertensive medications to control their blood pressure (Writing Group et al., 2010). Clinically, blood pressure measurements may lack accuracy, which can be attributed to various factors, including device limitations, cuff mis-sizing and misplacement, white-coat effect, masked hypertension, and lifestyle factors. The development of an arm phantom to simulate physiologic properties of a human arm and arterial BP waveforms may allow us to better assess the accuracy of non-invasive blood pressure (NIBP) monitors. The objective of this study are to: (1) Develop an arm phantom to replicate physiological properties of the human arm, and (2) Incorporate the arm phantom into a mock circulatory flow loop to simulate different physiological blood pressure readings on the bench. A tissue mimicking material, styrene-ethylene-butylene-styrene (SEBS), a co-block polymer was used to develop the arm phantom for in-vitro testing. To determine the optimal mechanical properties for the arm phantom, individual arm components were isolated and tested. A protocol was developed to evaluate various components for optimal arm phantom development. Mechanical testing was conducted on 10%, 15%, and 20% SEBS gel samples for modulus of elasticity measurements in order to simulate physiological properties of the human arm. As a result of the SEBS polymer being a new material for this application, this investigation will contribute to resolving the limitations that occurred during experimentation. In this study, we demonstrated that although SEBS polymer may be an ideal material to use for simulating

  1. Lattice Boltzmann equation calculation of internal, pressure-driven turbulent flow

    International Nuclear Information System (INIS)

    Hammond, L A; Halliday, I; Care, C M; Stevens, A

    2002-01-01

    We describe a mixing-length extension of the lattice Boltzmann approach to the simulation of an incompressible liquid in turbulent flow. The method uses a simple, adaptable, closure algorithm to bound the lattice Boltzmann fluid incorporating a law-of-the-wall. The test application, of an internal, pressure-driven and smooth duct flow, recovers correct velocity profiles for Reynolds number to 1.25 x 10 5 . In addition, the Reynolds number dependence of the friction factor in the smooth-wall branch of the Moody chart is correctly recovered. The method promises a straightforward extension to other curves of the Moody chart and to cylindrical pipe flow

  2. 40 CFR 60.274a - Monitoring of operations.

    Science.gov (United States)

    2010-07-01

    ... system is in use, and a furnace static pressure gauge is installed according to paragraph (f) of this... volumetric flow rate through each separately ducted hood; or install, calibrate, and maintain a monitoring device that continuously records the volumetric flow rate at the control device inlet and check and...

  3. Results of ambulatory arterial blood pressure monitoring in children with obesity

    Directory of Open Access Journals (Sweden)

    Faruk Öktem

    2010-12-01

    Full Text Available Objectives: The relationship between obesity and essential hypertension is well known. In this study, we aimed to evaluate ambulatory arterial blood pressure monitoring of obese and non-obese children who had similar demographic characteristics.Materials and methods: Seventy one children and adolescents (n=39 obesity, n=32 controls were studied. Blood pressure of the children were measured by 24 hour ambulatory blood pressure monitoring device.Results: Obese children had significantly higher mean blood pressure values (systolic 121.9±11.7 mmHg, diastolic 70.2±5.3 mmHg than control subjects (systolic 109.3±6.7 mmHg, diastolic 65.1±4.6 mmHg, p0.05. Blood pressure load was found to be increased in obese children compared to the controls (%13.6±12.9 and %2.6±3.4, respectively; p<0.05. Serum total cholesterol and LDL-cholesterol levels of obese children (181.1±33.4 and 131.1±23.1mg/dl were significantly higher than those of the controls (134.3±11.1 and 103.3±14.2 mg/dl, p<0.05.Conclusions: Obesity in children and adolescents should not be regarded as variations of normality, but as abnormality with an extremely high risk for the development of hypertension and hyperlipidemia in adulthood.

  4. Pressure fluctuations induced by fluid flow in singular points of industrial circuits

    International Nuclear Information System (INIS)

    Gibert, R.J.; Villard, B.

    1977-01-01

    Flow singularities (enlargements, bards, valves, tees,...) generate in the circuits of industrial plants wall pressure fluctuations which are the main cause of vibration. Two types of pressure fluctuations can be considered. - 'Local ' fluctuations: They are associated to the unsteadiness downstream from the singularity. These fluctuations may be characterized by frequency spectra, correlation length and phase lags. These parameters are used to calculate forces on the walls of the circuit. - 'Acoustic' fluctuations: The singularity acts as an acoustical source; its frequency spectrum and the acoustical transfer function of the circuit are needed to evaluate the acoustical level at any point. A methodical study of the most current singularities has been performed at C.E.A./D.E.M.T.: - On one hand a theory of noise generation by unsteady flow in internal acoustics has been developed. This theory uses the basic idea initiated by LIGHTILL. As a result it is shown that the plane wave propagation is a valid assumption and that a singularity can be acoustically modelled by a pressure and a mass-flow-rate discontinuities. Both are random functions of time, the spectra of which are determined from the local fluctuations characteristics. - On the other hand, characteristics of several singularities have been measured: (i) Intercorrelation spectra of local pressure fluctuations. (ii) Autocorrelation spectra of associated acoustical sources (the measure of the acoustical pressures in the experimental circuit are interpreted by using the D.E.M.T. computer code VIBRAPHONE which gives the acoustical response of a complex circuit). (Auth.)

  5. Assessment of fluctuating pressure gradient using acceleration spectra in near wall flows

    Science.gov (United States)

    Cadel, Daniel; Lowe, K. Todd

    2015-11-01

    Separation of contributions to the fluctuating acceleration from pressure gradient fluctuations and viscous shear fluctuations in the frequency domain is examined in a turbulent boundary layer. Past work leveraging turbulent accelerations for pressure gradient measurements has neglected the viscous shear term from the momentum equation--an invalid assumption in the case of near wall flows. The present study seeks to account for the influence of the viscous shear term and spectrally reject its contribution, which is thought to be concentrated at higher frequencies. Spectra of velocity and acceleration fluctuations in a flat plate, zero pressure gradient turbulent boundary layer at a momentum thickness Reynolds number of 7500 are measured using a spatially resolving three-component laser Doppler velocimeter. This canonical case data is applied for validation of the spectral approach for future application in more complex aerodynamic flows.

  6. A meshless scheme for incompressible fluid flow using a velocity-pressure correction method

    KAUST Repository

    Bourantas, Georgios

    2013-12-01

    A meshless point collocation method is proposed for the numerical solution of the steady state, incompressible Navier-Stokes (NS) equations in their primitive u-v-p formulation. The flow equations are solved in their strong form using either a collocated or a semi-staggered "grid" configuration. The developed numerical scheme approximates the unknown field functions using the Moving Least Squares approximation. A velocity, along with a pressure correction scheme is applied in the context of the meshless point collocation method. The proposed meshless point collocation (MPC) scheme has the following characteristics: (i) it is a truly meshless method, (ii) there is no need for pressure boundary conditions since no pressure constitutive equation is solved, (iii) it incorporates simplicity and accuracy, (iv) results can be obtained using collocated or semi-staggered "grids", (v) there is no need for the usage of a curvilinear system of coordinates and (vi) it can solve steady and unsteady flows. The lid-driven cavity flow problem, for Reynolds numbers up to 5000, has been considered, by using both staggered and collocated grid configurations. Following, the Backward-Facing Step (BFS) flow problem was considered for Reynolds numbers up to 800 using a staggered grid. As a final example, the case of a laminar flow in a two-dimensional tube with an obstacle was examined. © 2013 Elsevier Ltd.

  7. CSF Flow in the Brain in the Context of Normal Pressure Hydrocephalus.

    Science.gov (United States)

    Bradley, W G

    2015-05-01

    CSF normally flows back and forth through the aqueduct during the cardiac cycle. During systole, the brain and intracranial vasculature expand and compress the lateral and third ventricles, forcing CSF craniocaudad. During diastole, they contract and flow through the aqueduct reverses. Hyperdynamic CSF flow through the aqueduct is seen when there is ventricular enlargement without cerebral atrophy. Therefore, patients presenting with clinical normal pressure hydrocephalus who have hyperdynamic CSF flow have been found to respond better to ventriculoperitoneal shunting than those with normal or decreased CSF flow. Patients with normal pressure hydrocephalus have also been found to have larger intracranial volumes than sex-matched controls, suggesting that they may have had benign external hydrocephalus as infants. While their arachnoidal granulations clearly have decreased CSF resorptive capacity, it now appears that this is fixed and that the arachnoidal granulations are not merely immature. Such patients appear to develop a parallel pathway for CSF to exit the ventricles through the extracellular space of the brain and the venous side of the glymphatic system. This pathway remains functional until late adulthood when the patient develops deep white matter ischemia, which is characterized histologically by myelin pallor (ie, loss of lipid). The attraction between the bare myelin protein and the CSF increases resistance to the extracellular outflow of CSF, causing it to back up, resulting in hydrocephalus. Thus idiopathic normal pressure hydrocephalus appears to be a "2 hit" disease: benign external hydrocephalus in infancy followed by deep white matter ischemia in late adulthood. © 2015 by American Journal of Neuroradiology.

  8. The linearized pressure Poisson equation for global instability analysis of incompressible flows

    Science.gov (United States)

    Theofilis, Vassilis

    2017-12-01

    The linearized pressure Poisson equation (LPPE) is used in two and three spatial dimensions in the respective matrix-forming solution of the BiGlobal and TriGlobal eigenvalue problem in primitive variables on collocated grids. It provides a disturbance pressure boundary condition which is compatible with the recovery of perturbation velocity components that satisfy exactly the linearized continuity equation. The LPPE is employed to analyze instability in wall-bounded flows and in the prototype open Blasius boundary layer flow. In the closed flows, excellent agreement is shown between results of the LPPE and those of global linear instability analyses based on the time-stepping nektar++, Semtex and nek5000 codes, as well as with those obtained from the FreeFEM++ matrix-forming code. In the flat plate boundary layer, solutions extracted from the two-dimensional LPPE eigenvector at constant streamwise locations are found to be in very good agreement with profiles delivered by the NOLOT/PSE space marching code. Benchmark eigenvalue data are provided in all flows analyzed. The performance of the LPPE is seen to be superior to that of the commonly used pressure compatibility (PC) boundary condition: at any given resolution, the discrete part of the LPPE eigenspectrum contains converged and not converged, but physically correct, eigenvalues. By contrast, the PC boundary closure delivers some of the LPPE eigenvalues and, in addition, physically wrong eigenmodes. It is concluded that the LPPE should be used in place of the PC pressure boundary closure, when BiGlobal or TriGlobal eigenvalue problems are solved in primitive variables by the matrix-forming approach on collocated grids.

  9. Spatial distribution of cavitation-shock-pressure around a jet-flow gate-valve

    International Nuclear Information System (INIS)

    Oba, Risaburo; Takayama, Kazuyoshi; Ito, Yukio; Miyakura, Hideto; Nozaki, Satoru; Ishige, Tadashi; Sonoda, Shuji; Sakamoto, Kenji.

    1987-01-01

    To make clear the mechanism of cavitation erosion, the spatial distribution of cavitation shock pressures were quantitatively measured by a pressure sensitive sheet in the 1/10 scale model of a jet-flow gate-valve, for various valve-openings and cavitation numbers. The dynamic pressure response of the sheet was corrected by the shock wave generated from detonation explosives. It is made clear that the erosive shock pressures are distributed in a limited part of the whole cavitation region, and the safety region without the fatal cavitation erosion is defined. (author)

  10. Monitoring individual traffic flows within the ATLAS TDAQ network

    International Nuclear Information System (INIS)

    Sjoen, R; Batraneanu, S M; Leahu, L; Martin, B; Al-Shabibi, A; Stancu, S; Ciobotaru, M

    2010-01-01

    The ATLAS data acquisition system consists of four different networks interconnecting up to 2000 processors using up to 200 edge switches and five multi-blade chassis devices. The architecture of the system has been described in [1] and its operational model in [2]. Classical, SNMP-based, network monitoring provides statistics on aggregate traffic, but for performance monitoring and troubleshooting purposes there was an imperative need to identify and quantify single traffic flows. sFlow [3] is an industry standard based on statistical sampling which attempts to provide a solution to this. Due to the size of the ATLAS network, the collection and analysis of the sFlow data from all devices generates a data handling problem of its own. This paper describes how this problem is addressed by making it possible to collect and store data either centrally or distributed according to need. The methods used to present the results in a relevant fashion for system analysts are discussed and we explore the possibilities and limitations of this diagnostic tool, giving an example of its use in solving system problems that arise during the ATLAS data taking.

  11. Dependence of intramyocardial pressure and coronary flow on ventricular loading and contractility: a model study.

    Science.gov (United States)

    Bovendeerd, Peter H M; Borsje, Petra; Arts, Theo; van De Vosse, Frans N

    2006-12-01

    The phasic coronary arterial inflow during the normal cardiac cycle has been explained with simple (waterfall, intramyocardial pump) models, emphasizing the role of ventricular pressure. To explain changes in isovolumic and low afterload beats, these models were extended with the effect of three-dimensional wall stress, nonlinear characteristics of the coronary bed, and extravascular fluid exchange. With the associated increase in the number of model parameters, a detailed parameter sensitivity analysis has become difficult. Therefore we investigated the primary relations between ventricular pressure and volume, wall stress, intramyocardial pressure and coronary blood flow, with a mathematical model with a limited number of parameters. The model replicates several experimental observations: the phasic character of coronary inflow is virtually independent of maximum ventricular pressure, the amplitude of the coronary flow signal varies about proportionally with cardiac contractility, and intramyocardial pressure in the ventricular wall may exceed ventricular pressure. A parameter sensitivity analysis shows that the normalized amplitude of coronary inflow is mainly determined by contractility, reflected in ventricular pressure and, at low ventricular volumes, radial wall stress. Normalized flow amplitude is less sensitive to myocardial coronary compliance and resistance, and to the relation between active fiber stress, time, and sarcomere shortening velocity.

  12. Ocular Perfusion Pressure and Pulsatile Ocular Blood Flow in Normal and Systemic Hypertensive Patients.

    Science.gov (United States)

    Kanadani, Fabio N; Figueiredo, Carlos R; Miranda, Rafaela Morais; Cunha, Patricia Lt; M Kanadani, Tereza Cristina; Dorairaj, Syril

    2015-01-01

    Glaucomatous neuropathy can be a consequence of insufficient blood supply, increase in intraocular pressure (IOP), or other risk factors that diminish the ocular blood flow. To determine the ocular perfusion pressure (OPP) in normal and systemic hypertensive patients. One hundred and twenty-one patients were enrolled in this prospective and comparative study and underwent a complete ophthalmologic examination including slit lamp examination, Goldmann applanation tonometry, stereoscopic fundus examination, and pulsatile ocular blood flow (POBF) measurements. The OPP was calculated as being the medium systemic arterial pressure (MAP) less the IOP. Only right eye values were considered for calculations using Student's t-test. The mean age of the patients was 57.5 years (36-78), and 68.5% were women. There was a statistically significant difference in the OPP of the normal and systemic hypertensive patients (p cite this article: Kanadani FN, Figueiredo CR, Miranda RM, Cunha PLT, Kanadani TCM, Dorairaj S. Ocular Perfusion Pressure and Pulsatile Ocular Blood Flow in Normal and Systemic Hypertensive Patients. J Curr Glaucoma Pract 2015;9(1):16-19.

  13. Measurement of pressure distributions and velocity fields of water jet intake flow

    International Nuclear Information System (INIS)

    Jeong, Eun Ho; Yoon, Sang Youl; Kwon, Seong Hoon; Chun, Ho Hwan; Kim, Mun Chan; Kim, Kyung Chun

    2002-01-01

    Waterjet propulsion system can avoid cavitation problem which is being arised conventional propeller propulsion system. The main issue of designing waterjet system is the boundary layer separation at ramp and lib of water inlet. The flow characteristics are highly depended on Jet to Velocity Ratio(JVR) as well as the intake geometry. The present study is conducted in a wind tunnel to provide accurate pressure destribution at the inlet wall and velocity field of the inlet and exit planes. Particle image velocimetry technique is used to obtain detail velocity fields. Pressure distributions and velocity field are discussed with accelerating and deaccelerating flow zones and the effect of JVR

  14. NMR reaction monitoring in flow synthesis

    Directory of Open Access Journals (Sweden)

    M. Victoria Gomez

    2017-02-01

    Full Text Available Recent advances in the use of flow chemistry with in-line and on-line analysis by NMR are presented. The use of macro- and microreactors, coupled with standard and custom made NMR probes involving microcoils, incorporated into high resolution and benchtop NMR instruments is reviewed. Some recent selected applications have been collected, including synthetic applications, the determination of the kinetic and thermodynamic parameters and reaction optimization, even in single experiments and on the μL scale. Finally, software that allows automatic reaction monitoring and optimization is discussed.

  15. Implantable intraocular pressure monitoring systems: Design considerations

    KAUST Repository

    Arsalan, Muhammad

    2013-12-01

    Design considerations and limitations of implantable Intraocular Pressure Monitoring (IOPM) systems are presented in this paper. Detailed comparison with the state of the art is performed to highlight the benefits and challenges of the proposed design. The system-on-chip, presented here, is battery free and harvests energy from incoming RF signals. This low-cost design, in standard CMOS process, does not require any external components or bond wires to function. This paper provides useful insights to the designers of implantable wireless sensors in terms of design choices and associated tradeoffs. © 2013 IEEE.

  16. Implantable intraocular pressure monitoring systems: Design considerations

    KAUST Repository

    Arsalan, Muhammad; Ouda, Mahmoud H.; Marnat, Loic; Shamim, Atif; Salama, Khaled N.

    2013-01-01

    Design considerations and limitations of implantable Intraocular Pressure Monitoring (IOPM) systems are presented in this paper. Detailed comparison with the state of the art is performed to highlight the benefits and challenges of the proposed design. The system-on-chip, presented here, is battery free and harvests energy from incoming RF signals. This low-cost design, in standard CMOS process, does not require any external components or bond wires to function. This paper provides useful insights to the designers of implantable wireless sensors in terms of design choices and associated tradeoffs. © 2013 IEEE.

  17. Two-phase pressure drop and flow visualization of FC-72 in a silicon microchannel heat sink

    International Nuclear Information System (INIS)

    Megahed, Ayman; Hassan, Ibrahim

    2009-01-01

    The rapid development of two-phase microfluidic devices has triggered the demand for a detailed understanding of the flow characteristics inside microchannel heat sinks to advance the cooling process of micro-electronics. The present study focuses on the experimental investigation of pressure drop characteristics and flow visualization of a two-phase flow in a silicon microchannel heat sink. The microchannel heat sink consists of a rectangular silicon chip in which 45 rectangular microchannels were chemically etched with a depth of 276 μm, width of 225 μm, and a length of 16 mm. Experiments are carried out for mass fluxes ranging from 341 to 531 kg/m 2 s and heat fluxes from 60.4 to 130.6 kW/m 2 using FC-72 as the working fluid. Bubble growth and flow regimes are observed using high speed visualization. Three major flow regimes are identified: bubbly, slug, and annular. The frictional two-phase pressure drop increases with exit quality for a constant mass flux. An assessment of various pressure drop correlations reported in the literature is conducted for validation. A new general correlation is developed to predict the two-phase pressure drop in microchannel heat sinks for five different refrigerants. The experimental pressure drops for laminar-liquid laminar-vapor and laminar-liquid turbulent-vapor flow conditions are predicted by the new correlation with mean absolute errors of 10.4% and 14.5%, respectively.

  18. Numerical study of pressure fluctuations transfer law in different flow rate of turbine mode in a prototype pump turbine

    International Nuclear Information System (INIS)

    Sun, Y K; Zuo, Z G; Liu, S H; Wu, Y L; Liu, J T; Qin, D Q; Wei, X Z

    2013-01-01

    Numerical simulation using SST k-w turbulence model was carried out, to predict pressure fluctuation transfer law in turbine mode. Three operating points with different mass flow rates are simulated. The results of numerical simulation show that, the amplitude and frequency of pressure fluctuations in different positions are very different. The transfer law of amplitude and frequency of pressure fluctuations change with different position and different mass flow rate. Blade passing frequency (BPF) is the first dominant frequency in vaneless space, while component in this frequency got smaller in the upstream and downstream of vaneless space when the mass flow is set. Furthermore triple blade passing frequency (3BPF) component obtained a different transfer law through the whole flow passage. The amplitude and frequency of pressure fluctuations is also different in different circumference position of vaneless space. When the mass flow is different, the distribution of pressure fluctuations in circumference is different. The frequency component of pressure fluctuations in all the positions is different too

  19. Blood pressure and mesenteric blood flow in the rat during infusion of biogenic amines. Influence of a supralethal irradiation

    International Nuclear Information System (INIS)

    Timmermans, R.; Gerber, G.B.

    1979-01-01

    The action of biogenic amines (noradrenaline, dopamine), infused at different concentration into the aorta of the urethane anesthetized control and irradiated rats for 2 min., was followed on the basis of systemic blood pressure and mesenteric blood flow. The mesenteric blood flow was measured by means of an electromagnetic flow meter. The changes observed i.e. after dopamine an increase in pressure and flow, after noradrenaline an increase in pressure and a decrease in flow with an increase after infusion had been stopped, correspond to those obtained in larger animals. In many, but not in all cases, the response is proportional to the log of the concentration of the amine infused. Irradiation with 2 kR, i.e. a dose which causes the animals to die from the gastrointestinal syndrome after 3 days modified the response to dopamine and noradrenaline. The changes are, for noradrenaline, a greater pressure and a lower flow responses and for dopamine a greater pressure response at low and middle doses [fr

  20. Blood pressure and mesenteric blood flow in the rat during infusion of biogenic amines. Influence of a supralethal irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Timmermans, R; Gerber, G B [Centre d' Etude de l' Energie Nucleaire, Mol (Belgium)

    1978-01-01

    The action of biogenic amines (noradrenaline, dopamine), infused at different concentration into the aorta of the urethane anesthetized control and irradiated rats for 2 min., was followed on the basis of systemic blood pressure and mesenteric blood flow. The mesenteric blood flow was measured by means of an electromagnetic flow meter. The changes observed i.e. after dopamine an increase in pressure and flow, after noradrenaline an increase in pressure and a decrease in flow with an increase after infusion had been stopped, correspond to those obtained in larger animals. In many, but not in all cases, the response is proportional to the log of the concentration of the amine infused. Irradiation with 2 kR, i.e. a dose which causes the animals to die from the gastrointestinal syndrome after 3 days, modified the response to dopamine and noradrenaline. The changes are, for noradrenaline, a greater pressure and a lower flow responses and for dopamine a greater pressure response at low and middle doses.

  1. Proposal of evaluation method of tsunami wave pressure using 2D depth-integrated flow simulation

    International Nuclear Information System (INIS)

    Arimitsu, Tsuyoshi; Ooe, Kazuya; Kawasaki, Koji

    2012-01-01

    To design and construct land structures resistive to tsunami force, it is most essential to evaluate tsunami pressure quantitatively. The existing hydrostatic formula, in general, tended to underestimate tsunami wave pressure under the condition of inundation flow with large Froude number. Estimation method of tsunami pressure acting on a land structure was proposed using inundation depth and horizontal velocity at the front of the structure, which were calculated employing a 2D depth-integrated flow model based on the unstructured grid system. The comparison between the numerical and experimental results revealed that the proposed method could reasonably reproduce the vertical distribution of the maximum tsunami pressure as well as the time variation of the tsunami pressure exerting on the structure. (author)

  2. Ambulatory blood pressure monitoring in clinical trials with antihypertensive agents

    NARCIS (Netherlands)

    A.H. van den Meiracker (Anton)

    1995-01-01

    textabstractAmbulatory blood pressure monitoring (ABPM) is being used increasingly for the evaluation of antihypertensive agents in clinical trials. In this brief review several aspects of ABPM are discussed. In particular, attention is paid to the extent to which ABPM is subject to a placebo

  3. Development of a risk monitoring system for nuclear power plants based on GO-FLOW methodology

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Jun, E-mail: youngjun51@hotmail.com [College of Nuclear Science and Technology, Harbin Engineering University, No. 145 Nantong Street, Nangang District, Harbin 150001 (China); Yang, Ming, E-mail: yangming@hrbeu.edu.cn [College of Nuclear Science and Technology, Harbin Engineering University, No. 145 Nantong Street, Nangang District, Harbin 150001 (China); Yoshikawa, Hidekazu, E-mail: yosikawa@kib.biglobe.ne.jp [Symbio Community Forum, Kyoto (Japan); Yang, Fangqing, E-mail: yfq613@163.com [China Nuclear Power Technology Research Institute, 518000 (China)

    2014-10-15

    Highlights: • A method for developing Living PSA is proposed. • Living PSA is easy to update with online modification to system model file. • A risk monitoring system is designed and developed using the GO-FLOW. • The risk monitoring system is useful for plant daily operation risk management. - Abstract: The paper presents a risk monitoring system developed based on GO-FLOW methodology which is a success-oriented system reliability modeling technique for phased mission as well as time-dependent problems analysis. The risk monitoring system is designed to receive information on plant configuration changes either from equipment failures, operator interventions, or maintenance activities, then update the Living PSA model with online modification to the system GO-FLOW model file which contains all the functional modes of equipment represented by a proposed generalized GO-FLOW modeling structure, and display risk values graphically. The risk monitoring system can be used to assist safety engineers and plant operators in their maintenance management and daily operation risk management at NPPs.

  4. Development of a risk monitoring system for nuclear power plants based on GO-FLOW methodology

    International Nuclear Information System (INIS)

    Yang, Jun; Yang, Ming; Yoshikawa, Hidekazu; Yang, Fangqing

    2014-01-01

    Highlights: • A method for developing Living PSA is proposed. • Living PSA is easy to update with online modification to system model file. • A risk monitoring system is designed and developed using the GO-FLOW. • The risk monitoring system is useful for plant daily operation risk management. - Abstract: The paper presents a risk monitoring system developed based on GO-FLOW methodology which is a success-oriented system reliability modeling technique for phased mission as well as time-dependent problems analysis. The risk monitoring system is designed to receive information on plant configuration changes either from equipment failures, operator interventions, or maintenance activities, then update the Living PSA model with online modification to the system GO-FLOW model file which contains all the functional modes of equipment represented by a proposed generalized GO-FLOW modeling structure, and display risk values graphically. The risk monitoring system can be used to assist safety engineers and plant operators in their maintenance management and daily operation risk management at NPPs

  5. Socio-economic status influences blood pressure control despite equal access to care

    DEFF Research Database (Denmark)

    Paulsen, M S; Andersen, M; Munck, A P

    2012-01-01

    OBJECTIVE: Denmark has a health care system with free and equal access to care irrespective of age and socio-economic status (SES). We conducted a cross-sectional study to investigate a possible association between SES and blood pressure (BP) control of hypertensive patients treated in general...... Statistics Denmark. The outcome measure was BP control defined as BP...

  6. Development of a generic system for real-time data access and remote control of multiple in-situ water quality monitoring instruments

    Science.gov (United States)

    Wright, S. A.; Bennett, G. E.; Andrews, T.; Melis, T. S.; Topping, D. J.

    2005-05-01

    Currently, in-situ monitoring of water quality parameters (e.g. water temperature, conductivity, turbidity) in the Colorado River ecosystem typically consists of deploying instruments in the river, retrieving them at a later date, downloading the datalogger, then examining the data; an arduous process in the remote settings of Grand Canyon. Under this protocol, data is not available real-time and there is no way to detect problems with the instrumentation until after retrieval. The next obvious stage in the development of in-situ monitoring in Grand Canyon was the advent of one-way telemetry, i.e. streaming data in real-time from the instrument to the office and/or the world-wide-web. This protocol allows for real-time access to data and the identification of instrumentation problems, but still requires a site visit to address instrument malfunctions, i.e. the user does not have the ability to remotely control the instrument. At some field sites, such as the Colorado River in Grand Canyon, site visitation is restricted by remoteness and lack of traditional access routes (i.e. roads). Even at less remote sites, it may still be desirable to have two-way communication with instruments in order to, for example, diagnose and potentially fix instrumentation problems, change sampling parameters to save battery power, etc., without having to visit the site. To this end, the U.S. Geological Survey, Grand Canyon Monitoring and Research Center, is currently developing and testing a high-speed, two-way communication system that allows for real-time data access and remote control of instrumentation. The approach tested relies on internet access and may be especially useful in areas where land-line or cellular connections are unavailable. The system is composed of off-the-shelf products, uses a commercial broadband satellite service, and is designed in a generic way such that any instrument that communicates through RS-232 communication (i.e. a serial port) is compatible with

  7. Brine flow up a borehole caused by pressure perturbation from CO2 storage: Static and dynamic evaluations

    Energy Technology Data Exchange (ETDEWEB)

    Birkholzer, J.T.; Nicot, J.-P.; Oldenburg, C.M.; Zhou, Q.; Kraemer, S.; Bandilla, K.W.

    2011-05-01

    Industrial-scale storage of CO{sub 2} in saline sedimentary basins will cause zones of elevated pressure, larger than the CO{sub 2} plume itself. If permeable conduits (e.g., leaking wells) exist between the injection reservoir and overlying shallow aquifers, brine could be pushed upwards along these conduits and mix with groundwater resources. This paper discusses the potential for such brine leakage to occur in temperature- and salinity-stratified systems. Using static mass-balance calculations as well as dynamic well flow simulations, we evaluate the minimum reservoir pressure that would generate continuous migration of brine up a leaking wellbore into a freshwater aquifer. Since the brine invading the well is denser than the initial fluid in the wellbore, continuous flow only occurs if the pressure perturbation in the reservoir is large enough to overcome the increased fluid column weight after full invasion of brine into the well. If the threshold pressure is exceeded, brine flow rates are dependent on various hydraulic (and other) properties, in particular the effective permeability of the wellbore and the magnitude of pressure increase. If brine flow occurs outside of the well casing, e.g., in a permeable fracture zone between the well cement and the formation, the fluid/solute transfer between the migrating fluid and the surrounding rock units can strongly retard brine flow. At the same time, the threshold pressure for continuous flow to occur decreases compared to a case with no fluid/solute transfer.

  8. Role of Coronary Myogenic Response in Pressure-Flow Autoregulation in Swine: A Meta-Analysis With Coronary Flow Modeling

    Science.gov (United States)

    Dick, Gregory M.; Namani, Ravi; Patel, Bhavesh; Kassab, Ghassan S.

    2018-01-01

    Myogenic responses (pressure-dependent contractions) of coronary arterioles play a role in autoregulation (relatively constant flow vs. pressure). Publications on myogenic reactivity in swine coronaries vary in caliber, analysis, and degree of responsiveness. Further, data on myogenic responses and autoregulation in swine have not been completely compiled, compared, and modeled. Thus, it has been difficult to understand these physiological phenomena. Our purpose was to: (a) analyze myogenic data with standard criteria; (b) assign results to diameter categories defined by morphometry; and (c) use our novel multiscale flow model to determine the extent to which ex vivo myogenic reactivity can explain autoregulation in vivo. When myogenic responses from the literature are an input for our model, the predicted coronary autoregulation approaches in vivo observations. More complete and appropriate data are now available to investigate the regulation of coronary blood flow in swine, a highly relevant model for human physiology and disease. PMID:29875686

  9. Role of Coronary Myogenic Response in Pressure-Flow Autoregulation in Swine: A Meta-Analysis With Coronary Flow Modeling

    Directory of Open Access Journals (Sweden)

    Gregory M. Dick

    2018-05-01

    Full Text Available Myogenic responses (pressure-dependent contractions of coronary arterioles play a role in autoregulation (relatively constant flow vs. pressure. Publications on myogenic reactivity in swine coronaries vary in caliber, analysis, and degree of responsiveness. Further, data on myogenic responses and autoregulation in swine have not been completely compiled, compared, and modeled. Thus, it has been difficult to understand these physiological phenomena. Our purpose was to: (a analyze myogenic data with standard criteria; (b assign results to diameter categories defined by morphometry; and (c use our novel multiscale flow model to determine the extent to which ex vivo myogenic reactivity can explain autoregulation in vivo. When myogenic responses from the literature are an input for our model, the predicted coronary autoregulation approaches in vivo observations. More complete and appropriate data are now available to investigate the regulation of coronary blood flow in swine, a highly relevant model for human physiology and disease.

  10. Gas bubble dimensions in Archean lava flows indicate low air pressure at 2.7 Ga

    Science.gov (United States)

    Som, S. M.; Buick, R.; Hagadorn, J.; Blake, T.; Perreault, J.; Harnmeijer, J.; Catling, D. C.

    2014-12-01

    Air pressure constrains atmospheric composition, which, in turn, is linked to the Earth system through biogeochemical cycles and fluxes of volatiles from and to the Earth's interior. Previous studies have only placed maximum levels on surface air pressure for the early Earth [1]. Here, we calculate an absolute value for Archean barometric pressure using gas bubble size (vesicle) distributions in uninflated basaltic lava flows that solidified at sea level 2.7 billion years ago in the Pilbara Craton, Western Australia. These vesicles have been filled in by secondary minerals deposited during metasomatism and so are now amydules, but thin sections show that infilling did not change vesicle dimensions. Amygdule dimensions are measured using high-resolution X-ray tomography from core samples obtained from the top and bottom of the lava flows. The modal size expressed at the top and at the bottom of an uninflated flow can be linked to atmospheric pressure using the ideal gas law. Such a technique has been verified as a paleoaltimeter using Hawaiian Quaternary lava flows [2]. We use statistical methods to estimate the mean and standard deviation of the volumetric size of the amygdules by applying 'bootstrap'resampling and the Central Limit Theorem. Our data indicate a surprisingly low atmospheric pressure. Greater nitrogen burial under anaerobic conditions likely explains lower pressure. Refs: [1] Som et al. (2012) Nature 484, 359-262. D. L. Sahagian et al. (2002) J. Geol., 110, 671-685.

  11. Blood flow and tissue oxygen pressures of liver and pancreas in rats: effects of volatile anesthetics and of hemorrhage.

    Science.gov (United States)

    Vollmar, B; Conzen, P F; Kerner, T; Habazettl, H; Vierl, M; Waldner, H; Peter, K

    1992-09-01

    The object of this investigation was to compare the effects of volatile anesthetics and of hemorrhage at comparable arterial blood pressures on splanchnic blood flow (radioactive microspheres) and tissue oxygenation of the liver and pancreas (surface PO2 [PSO2] electrodes). In contrast to earlier studies, we did not use identical minimum alveolar anesthetic concentration multiples as a reference to compare volatile anesthetics; rather, we used the splanchnic perfusion pressure. Under general anesthesia (intravenous chloralose) and controlled ventilation, 12 Sprague-Dawley rats underwent laparotomy to allow access to abdominal organs. Mean arterial pressure was decreased from 84 +/- 3 mm Hg (mean +/- SEM) at control to 50 mm Hg by 1.0 +/- 0.1 vol% halothane, 2.2 +/- 0.2 vol% enflurane, and 2.3 +/- 0.1 vol% isoflurane in a randomized sequence. For hemorrhagic hypotension, blood was withdrawn gradually until a mean arterial pressure of 50 mm Hg was attained. Volatile anesthetics and hemorrhage reduced cardiac output, and hepatic arterial, portal venous, and total hepatic blood flows by comparable degrees. Mean hepatic PSO2 decreased significantly from 30.7 +/- 2.6 mm Hg at control to 17.4 +/- 2 and 17.5 +/- 2 mm Hg during enflurane and isoflurane (each P less than 0.05) anesthesia, respectively. The decrease to 11.5 +/- 2.5 mm Hg was more pronounced during halothane anesthesia. Hemorrhagic hypotension was associated with the lowest hepatic PSO2 (3.4 +/- 1.3 mm Hg) and the highest number of hypoxic (0-5 mm Hg 86%) and anoxic PSO2 values (0 mm Hg 46%). Pancreatic blood flow and oxygenation remained unchanged from control during halothane and enflurane administration, whereas isoflurane increased both variables. Hemorrhagic hypotension slightly reduced pancreatic flow (-8%) but significantly decreased PSO2 from 58 +/- 5 mm Hg at control to 36 +/- 3 mm Hg, with 7% of all measured values in the hypoxic range. Thus, volatile anesthetics preserved pancreatic but not hepatic

  12. Pressure modulation algorithm to separate cerebral hemodynamic signals from extracerebral artifacts

    OpenAIRE

    Baker, Wesley B.; Parthasarathy, Ashwin B.; Ko, Tiffany S.; Busch, David R.; Abramson, Kenneth; Tzeng, Shih-Yu; Mesquita, Rickson C.; Durduran, Turgut; Greenberg, Joel H.; Kung, David K.; Yodh, Arjun G.

    2015-01-01

    We introduce and validate a pressure measurement paradigm that reduces extracerebral contamination from superficial tissues in optical monitoring of cerebral blood flow with diffuse correlation spectroscopy (DCS). The scheme determines subject-specific contributions of extracerebral and cerebral tissues to the DCS signal by utilizing probe pressure modulation to induce variations in extracerebral blood flow. For analysis, the head is modeled as a two-layer medium and is probed with long and s...

  13. Wearable and low-stress ambulatory blood pressure monitoring technology for hypertension diagnosis.

    Science.gov (United States)

    Altintas, Ersin; Takoh, Kimiyasu; Ohno, Yuji; Abe, Katsumi; Akagawa, Takeshi; Ariyama, Tetsuri; Kubo, Masahiro; Tsuda, Kenichiro; Tochikubo, Osamu

    2015-01-01

    We propose a highly wearable, upper-arm type, oscillometric-based blood pressure monitoring technology with low-stress. The low-stress is realized by new developments in the hardware and software design. In the hardware design, conventional armband; cuff, is almost halved in volume thanks to a flexible plastic core and a liquid bag which enhances the fitness and pressure uniformity over the arm. Reduced air bag volume enables smaller motor pump size and battery leading to a thinner, more compact and more wearable unified device. In the software design, a new prediction algorithm enabled to apply less stress (and less pain) on arm of the patient. Proof-of-concept experiments on volunteers show a high accuracy on both technologies. This paper mainly introduces hardware developments. The system is promising for less-painful and less-stressful 24-hour blood pressure monitoring in hypertension managements and related healthcare solutions.

  14. Clinical assessment of auto-positive end-expiratory pressure by diaphragmatic electrical activity during pressure support and neurally adjusted ventilatory assist.

    Science.gov (United States)

    Bellani, Giacomo; Coppadoro, Andrea; Patroniti, Nicolò; Turella, Marta; Arrigoni Marocco, Stefano; Grasselli, Giacomo; Mauri, Tommaso; Pesenti, Antonio

    2014-09-01

    Auto-positive end-expiratory pressure (auto-PEEP) may substantially increase the inspiratory effort during assisted mechanical ventilation. Purpose of this study was to assess whether the electrical activity of the diaphragm (EAdi) signal can be reliably used to estimate auto-PEEP in patients undergoing pressure support ventilation and neurally adjusted ventilatory assist (NAVA) and whether NAVA was beneficial in comparison with pressure support ventilation in patients affected by auto-PEEP. In 10 patients with a clinical suspicion of auto-PEEP, the authors simultaneously recorded EAdi, airway, esophageal pressure, and flow during pressure support and NAVA, whereas external PEEP was increased from 2 to 14 cm H2O. Tracings were analyzed to measure apparent "dynamic" auto-PEEP (decrease in esophageal pressure to generate inspiratory flow), auto-EAdi (EAdi value at the onset of inspiratory flow), and IDEAdi (inspiratory delay between the onset of EAdi and the inspiratory flow). The pressure necessary to overcome auto-PEEP, auto-EAdi, and IDEAdi was significantly lower in NAVA as compared with pressure support ventilation, decreased with increase in external PEEP, although the effect of external PEEP was less pronounced in NAVA. Both auto-EAdi and IDEAdi were tightly correlated with auto-PEEP (r = 0.94 and r = 0.75, respectively). In the presence of auto-PEEP at lower external PEEP levels, NAVA was characterized by a characteristic shape of the airway pressure. In patients with auto-PEEP, NAVA, compared with pressure support ventilation, led to a decrease in the pressure necessary to overcome auto-PEEP, which could be reliably monitored by the electrical activity of the diaphragm before inspiratory flow onset (auto-EAdi).

  15. Blood pressure and blood flow variation during postural change from sitting to standing: model development and validation

    DEFF Research Database (Denmark)

    Olufsen, M.S.; Ottesen, Johnny T.; Tran, H.T.

    2005-01-01

    Short-term cardiovascular responses to postural change from sitting to standing involve complex interactions between the autonomic nervous system, which regulates blood pressure, and cerebral autoregulation, which maintains cerebral perfusion. We present a mathematical model that can predict...... dynamic changes in beat-to-beat arterial blood pressure and middle cerebral artery blood flow velocity during postural change from sitting to standing. Our cardiovascular model utilizes 11 compartments to describe blood pressure, blood flow, compliance, and resistance in the heart and systemic circulation....... To include dynamics due to the pulsatile nature of blood pressure and blood flow, resistances in the large systemic arteries are modeled using nonlinear functions of pressure. A physiologically based submodel is used to describe effects of gravity on venous blood pooling during postural change. Two types...

  16. Effects of Restricted Fructose Access on Body Weight and Blood Pressure Circadian Rhythms

    Directory of Open Access Journals (Sweden)

    Danielle Senador

    2012-01-01

    Full Text Available High-fructose diet is known to produce cardiovascular and metabolic pathologies. The objective was to determine whether the timing of high fructose (10% liquid solution intake affect the metabolic and cardiovascular outcomes. Male C57BL mice with radiotelemetric probes were divided into four groups: (1 24 h water (control; (2 24 h fructose (F24; (3 12 h fructose during the light phase (F12L; (4 12 h fructose during the dark phase (F12D. All fructose groups had higher fluid intake. Body weight was increased in mice on restricted access with no difference in total caloric intake. Fasting glycemia was higher in groups with restricted access. F24 mice showed a fructose-induced blood pressure increase during the dark period. Blood pressure circadian rhythms were absent in F12L mice. Results suggest that the timing of fructose intake is an important variable in the etiology of cardiovascular and metabolic pathologies produced by high fructose consumption.

  17. Embedding piezoresistive pressure sensors to obtain online pressure profiles inside fiber composite laminates.

    Science.gov (United States)

    Moghaddam, Maryam Kahali; Breede, Arne; Brauner, Christian; Lang, Walter

    2015-03-27

    The production of large and complex parts using fiber composite materials is costly due to the frequent formation of voids, porosity and waste products. By embedding different types of sensors and monitoring the process in real time, the amount of wastage can be significantly reduced. This work focuses on developing a knowledge-based method to improve and ensure complete impregnation of the fibers before initiation of the resin cure. Piezoresistive and capacitive pressure sensors were embedded in fiber composite laminates to measure the real-time the pressure values inside the laminate. A change of pressure indicates resin infusion. The sensors were placed in the laminate and the resin was infused by vacuum. The embedded piezoresistive pressure sensors were able to track the vacuum pressure in the fiber composite laminate setup, as well as the arrival of the resin at the sensor. The pressure increase due to closing the resin inlet was also measured. In contrast, the capacitive type of sensor was found to be inappropriate for measuring these quantities. The following study demonstrates real-time monitoring of pressure changes inside the fiber composite laminate, which validate the use of Darcy's law in porous media to control the resin flow during infusion.

  18. Sensitivity of break-flow-partition on the containment pressure and temperature

    International Nuclear Information System (INIS)

    Kwon, Young Min; Song, Jin Ho; Lee, Sang Yong

    1994-01-01

    For the case of RCS blowdown into the vapor region of a containment at low pressure, the blowdown mixture will start to boil at the containment pressure and liquid will separate from the flow near the break location. The flashed steam is added to the containment atmosphere and liquid is falled to the sump. Analytically, the break flow can be divided into steam and liquid in a number of ways. Discussed in this study is three partition models and Instantaneous Mixing(IM) Model employed in different containment analysis computer codes. IM model is employed in the CONTRANS code developed by ABB-CE for containment thermodynamic analysis. The various partition models were applied to the double ended discharge leg slot break (DEDLS) LOCA which is containment design base accident (CDBA) for Ulchin 3 and 4 PSAR. It was shown that IM model is the most conservative for containment design pressure analysis. Results of the CONTRANS analyses are compared with those of UCN PSAR for which CONTEMPT-LT code was used

  19. Nitrous Oxide and Nitrous Oxide-Free Low-Flow Anesthesia Using Bispectral Index Monitoring: Effects on Hemodynamics, Recovery Times, Volatile Anesthetic Consumption and Costs

    Directory of Open Access Journals (Sweden)

    Bengü Gülhan Köksal

    2010-12-01

    Full Text Available Aim: In this study, we aimed to compare the effects of desfluraneN2O and desflurane-fentanyl combinations on hemodynamics, recovery times, volatile anesthetic consumption and costs in low-flow desflurane anesthesia by bispectral index (BIS monitoring of depth of anesthesia. Methods: After approval of ethics committee and obtaining patient consents, 60 patients were divided into two equal groups randomly. Non-invasive blood pressure measurement, ECG, SpO2 and BIS were monitored. All patients received 10 L .min-1 100% oxygen with mask for 5 minute before intubation. 2 mg.kg-1 propofol, 2 μg.kg-1 fentanyl and 0.6 mg.kg-1 rocuronium bromide were administered at induction in both groups. Desfluran 6% was chosen for anesthesia maintenance. Group 1 received 50% O2-N2O mixture in 6 L.min-1 and Group 2 received 50% O2-air mixture in 6 L.min-1 as carrier gas. Low-flow anesthesia (1 L.min-1 was started after a 10-min period of initial high flow (6 L.min-1. In Group 2, infusion of fentanyl was begun in 1 μg.kg.hour-1 rate. Desflurane level was adjusted at a main BIS value of 40-60. Blood pressure, heart rate, FiO2, etO2, FiN22, EtN2O, FiCO2, EtCO2, Fidesfluran and Etdesflurane were recorded. Results: There were no significant differences between the two groups in terms of heart rate, arterial blood pressure, settings of desfluran and recovery time. BIS values (p<0.001 and anesthetic agent costs (p<0.001 were higher in Group 2. Conclusion: Using fentanyl infusion instead of nitrous oxide in low flow-anesthesia with desflurane did not alter the hemodynamic parameters. Fentanyl infusion with medical air-oxygen as carrier gas is an alternative technique, but increases BIS values and anesthetic agent costs. (The Medical Bulletin of Haseki 2010; 48: 132-8

  20. Method and apparatus for monitoring oxygen partial pressure in air masks

    Science.gov (United States)

    Kelly, Mark E. (Inventor); Pettit, Donald R. (Inventor)

    2006-01-01

    Method and apparatus are disclosed for monitoring an oxygen partial pressure in an air mask and providing a tactile warning to the user. The oxygen partial pressure in the air mask is detected using an electrochemical sensor, the output signal from which is provided to a comparator. The comparator compares the output signal with a preset reference value or range of values representing acceptable oxygen partial pressures. If the output signal is different than the reference value or outside the range of values, the air mask is vibrated by a vibrating motor to alert the user to a potentially hypoxic condition.

  1. Flow Visualization at Cryogenic Conditions Using a Modified Pressure Sensitive Paint Approach

    Science.gov (United States)

    Watkins, A. Neal; Goad, William K.; Obara, Clifford J.; Sprinkle, Danny R.; Campbell, Richard L.; Carter, Melissa B.; Pendergraft, Odis C., Jr.; Bell, James H.; Ingram, JoAnne L.; Oglesby, Donald M.

    2005-01-01

    A modification to the Pressure Sensitive Paint (PSP) method was used to visualize streamlines on a Blended Wing Body (BWB) model at full-scale flight Reynolds numbers. In order to achieve these conditions, the tests were carried out in the National Transonic Facility operating under cryogenic conditions in a nitrogen environment. Oxygen is required for conventional PSP measurements, and several tests have been successfully completed in nitrogen environments by injecting small amounts (typically < 3000 ppm) of oxygen into the flow. A similar technique was employed here, except that air was purged through pressure tap orifices already existent on the model surface, resulting in changes in the PSP wherever oxygen was present. The results agree quite well with predicted results obtained through computational fluid dynamics analysis (CFD), which show this to be a viable technique for visualizing flows without resorting to more invasive procedures such as oil flow or minitufts.

  2. Experimental characterization of MHD pressure drop of liquid sodium flow under uniform magnetic field

    International Nuclear Information System (INIS)

    Kim, Hee Reyoung; Park, Jon Ho; Kim, Jong Man; Nam, Ho Yoon; Choi, Jong Hyun

    2001-01-01

    Magnetic field has many effects on the hydraulic pressure drop of fluids with high electrical conductivity. The theoretical solution about MHD pressure drop is sought for the uniform current density model with simplified physical geometry. Using the MHD equation in the rectangular duct of the sodium liquid flow under a transverse magnetic field, the electrical potential is sought in terms of the duct geometry and the electrical parameters of the liquid metal and duct material. By the product of the induced current inside the liquid metal and transverse magnetic field, the pressure gradients is found as a function of the duct size and the electrical conductivity of the liquid metal. The theoretically predicted pressure drop is compared with experimental results on the change of flow velocity and magnetic flux density

  3. Prediction of blood pressure and blood flow in stenosed renal arteries using CFD

    Science.gov (United States)

    Jhunjhunwala, Pooja; Padole, P. M.; Thombre, S. B.; Sane, Atul

    2018-04-01

    In the present work an attempt is made to develop a diagnostive tool for renal artery stenosis (RAS) which is inexpensive and in-vitro. To analyse the effects of increase in the degree of severity of stenosis on hypertension and blood flow, haemodynamic parameters are studied by performing numerical simulations. A total of 16 stenosed models with varying degree of stenosis severity from 0-97.11% are assessed numerically. Blood is modelled as a shear-thinning, non-Newtonian fluid using the Carreau model. Computational Fluid Dynamics (CFD) analysis is carried out to compute the values of flow parameters like maximum velocity and maximum pressure attained by blood due to stenosis under pulsatile flow. These values are further used to compute the increase in blood pressure and decrease in available blood flow to kidney. The computed available blood flow and secondary hypertension for varying extent of stenosis are mapped by curve fitting technique using MATLAB and a mathematical model is developed. Based on these mathematical models, a quantification tool is developed for tentative prediction of probable availability of blood flow to the kidney and severity of stenosis if secondary hypertension is known.

  4. Studies on MHD pressure drop and heat transfer of helium-lithium annular-mist flow in a transverse magnetic field

    International Nuclear Information System (INIS)

    Inoue, Akira; Aritomi, Masanori; Takahashi, Minoru; Matsuzaki, Mitsuo; Narita, Yoshihito; Yano, Toshikazu.

    1987-01-01

    Pressure drop and heat transfer coefficient of helium-lithium annular-mist flow in a rectangular duct were investigated experimentally under a transverse magnetic field at system pressure of 0.2 MPa. A ratio of MHD pressure drop to that of non-magnetic field increases with magnetic flux density and a mass flow rate ratio of lithium to helium in low helium velocity region. However, as increasing the helium velocity, the increment of MHD pressure drop with the magnetic flux density is much reduced and then becomes almost zero. At this condition, the MHD pressure drop of the annular-mist flow becomes much smaller than that of lithium single phase flow with the same lithium mass flow at the high magnetic flux density. Heat transfer coefficient ratio of the helium-lithium annular-mist flow to helium single phase in the non-magnetic field is well correlated by a ratio of the mass flow rate of lithium to helium. The heat transfer coefficient in the magnetic field increases with the magnetic flux density and then terminates at a certain value depending on the mass flow rate ratio and the helium velocity. These characteristics of the MHD pressure drop and the heat transfer in the magnetic field suggest that the helium-lithium annular-mist flow is effectively applicable to cooling of the high heat flux wall in a strong magnetic field like a first wall of a magnetic confinement fusion reactors. (author)

  5. Prediction of pressure drop and CCFL breakdown in countercurrent two-phase flow

    International Nuclear Information System (INIS)

    Ostrogorsky, A.G.; Gay, R.R.; Lahey, R.T. Jr.

    1983-01-01

    A steady-state analytical has been developed to predict channel pressure drop as a function of inlet vapor flow rate and applied heat flux during conditions of countercurrent two-phase flow. The interfacial constitutive relations utilized are flow surface dependent and allow for the existence of either smooth or way liquid films. A computer code was developed to solve the analytical model. Predictions of Δp versus vapor flow rate were found to agree favorably with experimental data from adiabatic, air/water systems. In addition, the model was used to predict countercurrent flow conditions in heated channels characteristic of a BWR/4 nuclear reactor fuel assembly

  6. Altered phase interactions between spontaneous blood pressure and flow fluctuations in type 2 diabetes mellitus: Nonlinear assessment of cerebral autoregulation

    Science.gov (United States)

    Hu, Kun; Peng, C. K.; Huang, Norden E.; Wu, Zhaohua; Lipsitz, Lewis A.; Cavallerano, Jerry; Novak, Vera

    2008-04-01

    Cerebral autoregulation is an important mechanism that involves dilatation and constriction in arterioles to maintain relatively stable cerebral blood flow in response to changes of systemic blood pressure. Traditional assessments of autoregulation focus on the changes of cerebral blood flow velocity in response to large blood pressure fluctuations induced by interventions. This approach is not feasible for patients with impaired autoregulation or cardiovascular regulation. Here we propose a newly developed technique-the multimodal pressure-flow (MMPF) analysis, which assesses autoregulation by quantifying nonlinear phase interactions between spontaneous oscillations in blood pressure and flow velocity during resting conditions. We show that cerebral autoregulation in healthy subjects can be characterized by specific phase shifts between spontaneous blood pressure and flow velocity oscillations, and the phase shifts are significantly reduced in diabetic subjects. Smaller phase shifts between oscillations in the two variables indicate more passive dependence of blood flow velocity on blood pressure, thus suggesting impaired cerebral autoregulation. Moreover, the reduction of the phase shifts in diabetes is observed not only in previously-recognized effective region of cerebral autoregulation (type 2 diabetes mellitus alters cerebral blood flow regulation over a wide frequency range and that this alteration can be reliably assessed from spontaneous oscillations in blood pressure and blood flow velocity during resting conditions. We also show that the MMPF method has better performance than traditional approaches based on Fourier transform, and is more suitable for the quantification of nonlinear phase interactions between nonstationary biological signals such as blood pressure and blood flow.

  7. Comparative study of heat transfer and pressure drop during flow boiling and flow condensation in minichannels

    Directory of Open Access Journals (Sweden)

    Mikielewicz Dariusz

    2014-09-01

    Full Text Available In the paper a method developed earlier by authors is applied to calculations of pressure drop and heat transfer coefficient for flow boiling and also flow condensation for some recent data collected from literature for such fluids as R404a, R600a, R290, R32,R134a, R1234yf and other. The modification of interface shear stresses between flow boiling and flow condensation in annular flow structure are considered through incorporation of the so called blowing parameter. The shear stress between vapor phase and liquid phase is generally a function of nonisothermal effects. The mechanism of modification of shear stresses at the vapor-liquid interface has been presented in detail. In case of annular flow it contributes to thickening and thinning of the liquid film, which corresponds to condensation and boiling respectively. There is also a different influence of heat flux on the modification of shear stress in the bubbly flow structure, where it affects bubble nucleation. In that case the effect of applied heat flux is considered. As a result a modified form of the two-phase flow multiplier is obtained, in which the nonadiabatic effect is clearly pronounced.

  8. Robustness and quality of precipitation and river flow data obtained through participatory monitoring and citizen scienc

    Science.gov (United States)

    Buytaert, W.; Ochoa-Tocachi, B. F.

    2016-12-01

    Apart for the most basic measurements of manual rain and staff gauges, hydrology and water resources are not an evident disciplines for the application of citizen science. High-resolution measurements require elaborate equipment, installation, and maintenance that is typically beyond the scope of non-scientists. Additionally, hydrological analysis has traditionally relied upon long time series of consistent accuracy and precision. Nevertheless, new opportunities for public participation in hydrological research are emerging, driven by increasingly affordable, robust, and more user-friendly technology. Here we analyse the results generated by participatory monitoring of river flow and precipitation in around 30 catchments in the tropical Andes. This monitoring network was set up through a collaborative effort between scientists, NGOs and local communities, with the intention to generate evidence about the impact of land-use change on streamflow. Monitoring was implemented using automatic but low-cost sensors operated and maintained by local users. Tipping bucket rain gauges are used for precipitation, and river flow is monitored with pressure transducers in combination with a V-notch weir to obtain a stable stage-discharge relation. Jointly, the sensors have now collected an equivalent of more than 30 years of data, with a measurement interval of typically 5 or 15 minutes. Analysing the data, we find that the observations themselves tend to be of a quality comparable to scientific observations. However, main issues are related to the continuity of the time series, as sensors eventually fail or run out of capacity in dataloggers or batteries in the most remote locations. Despite these shortcomings, the data have proven to be useful in characterizing land-use impacts well beyond what can be achieved with conventional data collection, thus filling long-standing gaps in local hydrological knowledge. Furthermore, we expect that the advent of new, more robust, resilient

  9. Automated measurement and monitoring of bioprocesses: key elements of the M(3)C strategy.

    Science.gov (United States)

    Sonnleitner, Bernhard

    2013-01-01

    The state-of-routine monitoring items established in the bioprocess industry as well as some important state-of-the-art methods are briefly described and the potential pitfalls discussed. Among those are physical and chemical variables such as temperature, pressure, weight, volume, mass and volumetric flow rates, pH, redox potential, gas partial pressures in the liquid and molar fractions in the gas phase, infrared spectral analysis of the liquid phase, and calorimetry over an entire reactor. Classical as well as new optical versions are addressed. Biomass and bio-activity monitoring (as opposed to "measurement") via turbidity, permittivity, in situ microscopy, and fluorescence are critically analyzed. Some new(er) instrumental analytical tools, interfaced to bioprocesses, are explained. Among those are chromatographic methods, mass spectrometry, flow and sequential injection analyses, field flow fractionation, capillary electrophoresis, and flow cytometry. This chapter surveys the principles of monitoring rather than compiling instruments.

  10. Patients’ blood pressure knowledge, perceptions and monitoring practices in community pharmacies

    OpenAIRE

    Lam, Jennifer Y.; Guirguis, Lisa M.

    2010-01-01

    Hypertension is a modifiable risk factor for cardiovascular disease. Despite this, patients often cannot or inaccurately estimate their risk factors.Objectives: In order to improve pharmacist interventions, we sought to: 1) find out patients’ knowledge about blood pressure (BP) and their self- monitoring behaviors and 2) identify the relationships between these two elements. Specifically, if evaluation of BP control were related to knowledge of one’s BP level and self-monitoring habits, and i...

  11. Noninvasive continuous blood pressure monitoring by the ClearSight system during robot-assisted laparoscopic radical prostatectomy.

    Science.gov (United States)

    Sakai, Yoko; Yasuo M, Tsutsumi; Oyama, Takuro; Murakami, Chiaki; Kakuta, Nami; Tanaka, Katsuya

    2018-01-01

    Robot-assisted laparoscopic radical prostatectomy (RALRP) is commonly performed in the surgical treatment of prostate cancer. However, the steep Trendelenburg position (25) and pneumoperitoneum required for this procedure can sometimes cause hemodynamic changes. Although blood pressure is traditionally monitored invasively during RALRP, the ClearSight system (BMEYE, Amsterdam, The Netherlands) enables a totally noninvasive and simple continuous blood pressure and cardiac output monitoring based on finger arterial pressure pulse contour analysis. We therefore investigated whether noninvasive continuous arterial blood pressure measurements using the ClearSight system were comparable to those obtained invasively in patients undergoing RALRP. Ten patients scheduled for RALRP with American Society of Anesthesiologists physical status I-II were included in this study. At each of the seven defined time points, noninvasive and invasive blood pressure measurements were documented and compared in each patient using Bland-Altman analysis. Although the blood pressure measured with the ClearSight system correlated with that measured invasively, a large difference between the values obtained by the two devices was noted. The ClearSight system was unable to detect blood pressure accurately during RALRP, suggesting that blood pressure monitoring using this device alone is not feasible in this small patient population. J. Med. Invest. 65:69-73, February, 2018.

  12. Frequency analyses of CSF flow on cine MRI in normal pressure hydrocephalus

    Energy Technology Data Exchange (ETDEWEB)

    Miyati, Tosiaki; Kasuga, Toshio; Koshida, Kichiro; Sanada, Shigeru; Onoguchi, Masahisa [Department of Radiological Technology, School of Health Sciences, Faculty of Medicine, Kanazawa University, 5-11-80, Kodatsuno, Kanazawa, Ishikawa 920-0942 (Japan); Mase, Mitsuhito; Yamada, Kazuo [Department of Neurosurgery, Nagoya City University Medical School, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi 467-8602 (Japan); Banno, Tatsuo [Department of Central Radiology, Nagoya City University Hospital, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi 467-8602 (Japan); Fujita, Hiroshi [Department of Information Science, Faculty of Engineering, Gifu University, Yanagido 1-1, Gifu 501-1193 (Japan)

    2003-05-01

    Our objective was to clarify intracranial cerebrospinal fluid (CSF) flow dynamics in normal-pressure hydrocephalus (NPH). Frequency analyses of CSF flow measured with phase-contrast cine MRI were performed. The CSF flow spectra in the aqueduct were determined in patients (n=51) with NPH, brain atrophy or asymptomatic ventricular dilation (VD), and in healthy volunteers (control group; n=25). The changes in CSF flow spectra were also analyzed after intravenous injection of acetazolamide. Moreover, a phase transfer function (PTF) calculated from the spectra of the driving vascular pulsation and CSF flow in the aqueduct were assessed. These values were compared with the pressure volume response (PVR). The amplitude in the NPH group was significantly larger than that in the VD or control group because of a decrease in compliance. The phase in the NPH group was significantly different from that in either the VD or the control group, but no difference was found between the VD and control groups. The amplitude increased in all groups after acetazolamide injection. The PTF in the NPH group was significantly larger than in the control group, and a positive correlation was noted between PTF and PVR. Frequency analyses of CSF flow measured by cine MRI make it possible to noninvasively obtain a more detailed picture of the pathophysiology of NPH. (orig.)

  13. Routine intracranial pressure monitoring in acute coma.

    Science.gov (United States)

    Forsyth, Rob J; Raper, Joseph; Todhunter, Emma

    2015-11-02

    We know that the brain damage resulting from traumatic and other insults is not due solely to the direct consequences of the primary injury. A significant and potentially preventable contribution to the overall morbidity arises from secondary hypoxic-ischaemic damage. Brain swelling accompanied by raised intracranial pressure (ICP) prevents adequate cerebral perfusion with well-oxygenated blood.Detection of raised ICP could be useful in alerting clinicians to the need to improve cerebral perfusion, with consequent reductions in brain injury. To determine whether routine ICP monitoring in severe coma of any cause reduces the risk of all-cause mortality or severe disability at final follow-up. We searched the Cochrane Injuries Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (OvidSP), EMBASE (OvidSP), CINAHL Plus, ISI Web of Science (SCI-EXPANDED & CPCI-S), clinical trials registries and reference lists. We ran the most recent search on 22 May 2015. All randomised controlled studies of real-time ICP monitoring by invasive or semi-invasive means in acute coma (traumatic or non-traumatic aetiology) versus clinical care without ICP monitoring (that is, guided only by clinical or radiological inference of the presence of raised ICP). Two authors (ET and RF) worked independently to identify the one study that met inclusion criteria. JR and RF independently extracted data and assessed risk of bias. We contacted study authors for additional information, including details of methods and outcome data. One randomized controlled trial (RCT) meeting the selection criteria has been identified to date.The included study had 324 participants. We judged risk of bias to be low for all categories except blinding of participants and personnel, which is not feasible for this intervention. There were few missing data, and we analysed all on an intention-to-treat basis.Participants could be 13 years of age or older (mean age of sample 29

  14. Alterations of Blood Flow Through Arteries Following Atherectomy and the Impact on Pressure Variation and Velocity.

    Science.gov (United States)

    Plourde, Brian D; Vallez, Lauren J; Sun, Biyuan; Nelson-Cheeseman, Brittany B; Abraham, John P; Staniloae, Cezar S

    2016-09-01

    Simulations were made of the pressure and velocity fields throughout an artery before and after removal of plaque using orbital atherectomy plus adjunctive balloon angioplasty or stenting. The calculations were carried out with an unsteady computational fluid dynamic solver that allows the fluid to naturally transition to turbulence. The results of the atherectomy procedure leads to an increased flow through the stenotic zone with a coincident decrease in pressure drop across the stenosis. The measured effect of atherectomy and adjunctive treatment showed decrease the systolic pressure drop by a factor of 2.3. Waveforms obtained from a measurements were input into a numerical simulation of blood flow through geometry obtained from medical imaging. From the numerical simulations, a detailed investigation of the sources of pressure loss was obtained. It is found that the major sources of pressure drop are related to the acceleration of blood through heavily occluded cross sections and the imperfect flow recovery downstream. This finding suggests that targeting only the most occluded parts of a stenosis would benefit the hemodynamics. The calculated change in systolic pressure drop through the lesion was a factor of 2.4, in excellent agreement with the measured improvement. The systolic and cardiac-cycle-average pressure results were compared with measurements made in a multi-patient study treated with orbital atherectomy and adjunctive treatment. The agreements between the measured and calculated systolic pressure drop before and after the treatment were within 3%. This excellent agreement adds further confidence to the results. This research demonstrates the use of orbital atherectomy to facilitate balloon expansion to restore blood flow and how pressure measurements can be utilized to optimize revascularization of occluded peripheral vessels.

  15. An assessment of acoustic emission for nuclear pressure vessel monitoring

    International Nuclear Information System (INIS)

    Scruby, C.B.

    1983-01-01

    Recent research has greatly improved our understanding of the basic mechanisms of deformation and fracture that generate detectable acoustic emission signals in structural steels. A critical review of the application of acoustic emission (AE) to the fabrication, proof testing and in-service monitoring of nuclear pressure vessels is presented in the light of this improved understanding. The detectability of deformation and fracture processes in pressure vessel steels is discussed, and recommendations made for improving source location accuracy and the development of quantitative source assessment techniques. Published data suggest that AE can make an important contribution to fabrication monitoring, and to the detection of defects in lower toughness materials during vessel proof testing. In high toughness materials, however, the signals generated during ductile crack growth may frequently be too weak for reliable detection. The feasibility of AE for continuous monitoring has not yet been adequately demonstrated because of high background noise levels and uncertainty about AE signal strengths from the defect growth processes that occur in service. In-service leak detection by AE shows considerable promise. It is recommended that further tests are carried out with realistic defects, and under realistic conditions of loading (including thermal shock and fatigue) and of environment. (author)

  16. Monitoring the data flow of LHCb’s data acquisition system

    CERN Document Server

    Svantesson, David; Rainer, S

    2010-01-01

    The data acquisition system of the Large Hadron Collider beauty (LHCb) experiment need to read out huge amount of data. Monitoring is done for each subsystem but there exist no system to monitor the overall data flow. The aim of this work has been to design a system where the data rates can be vied continuously and making it possible to do an exact consistency check after the run to ensure no data are lost. This involves collecting and processing all necessary data from each subsystem and integrate it into the experiment control system for displaying it to the operators. The challenges are to communicate and collect data from all stages of the data acquisitions system which uses different techniques and data formats. The size of the system also makes it a challenge to gather all statistics in real time. The system must also be able to support partitioning. The result was to build a data flow monitoring system, that acquire statistics from all stages of the data acquisition, process it and display it in the ex...

  17. Recent Advances in Point-of-Access Water Quality Monitoring

    Science.gov (United States)

    Korostynska, O.; Arshak, K.; Velusamy, V.; Arshak, A.; Vaseashta, Ashok

    Clean water is one of our most valuable natural resources. In addition to providing safe drinking water it assures functional ecosystems that support fisheries and recreation. Human population growth and its associated increased demands on water pose risks to maintaining acceptable water quality. It is vital to assess source waters and the aquatic systems that receive inputs from industrial waste and sewage treatment plants, storm water systems, and runoff from urban and agricultural lands. Rapid and confident assessments of aquatic resources form the basis for sound environmental management. Current methods engaged in tracing the presence of various bacteria in water employ bulky laboratory equipment and are time consuming. Thus, real-time water quality monitoring is essential for National and International Health and Safety. Environmental water monitoring includes measurements of physical characteristics (e.g. pH, temperature, conductivity), chemical parameters (e.g. oxygen, alkalinity, nitrogen and phosphorus compounds), and abundance of certain biological taxa. Monitoring could also include assays of biological activity such as alkaline phosphatase, tests for toxins such as microcystins and direct measurements of pollutants such as heavy metals or hydrocarbons. Real time detection can significantly reduce the level of damage and also the cost to remedy the problem. This paper presents overview of state-of-the-art methods and devices used for point-of-access water quality monitoring and suggest further developments in this area.

  18. The Role of Central Blood Pressure Monitoring in the Management of Hypertension.

    Science.gov (United States)

    Ochoa, Adrian; Patarroyo-Aponte, Gabriel; Rahman, Mahboob

    2018-04-19

    Central blood pressure is a novel predictor of cardiovascular risk that can be measured in the clinical setting using currently available technology. This paper will review current available methods of central blood pressure monitoring as well as its impact in cardiac and renal disease. Both aortic and carotid systolic blood pressure are independently associated with cardiovascular mortality and serious cardiac events. Furthermore, studies show that systolic aortic blood pressure has been shown to be superior predictor of cardiovascular as compared to brachial blood pressure. Inhibitors of the renin angiotensin axis may have a beneficial effect on central blood pressure; however, long term studies evaluating the impact of lowering central blood pressure on clinical outcomes are lacking. Central blood pressure is a good predictor of cardiovascular risk. As more studies emerge demonstrating the value of central blood pressure as a therapeutic target, it is possible that targeting central blood pressure may become an important part of the armamentarium to lower cardiovascular risk.

  19. Pressure Measurement in Supersonic Air Flow by Differential Absorptive Laser-Induced Thermal Acoustics

    Science.gov (United States)

    Hart, Roger C.; Herring, Gregory C.; Balla, Robert J.

    2007-01-01

    Nonintrusive, off-body flow barometry in Mach-2 airflow has been demonstrated in a large-scale supersonic wind tunnel using seedless laser-induced thermal acoustics (LITA). The static pressure of the gas flow is determined with a novel differential absorption measurement of the ultrasonic sound produced by the LITA pump process. Simultaneously, stream-wise velocity and static gas temperature of the same spatially-resolved sample volume were measured with this nonresonant time-averaged LITA technique. Mach number, temperature and pressure have 0.2%, 0.4%, and 4% rms agreement, respectively, in comparison with known free-stream conditions.

  20. Pressure drop and heat transfer of a mercury single-phase flow and an air-mercury two-phase flow in a helical tube under a strong magnetic field

    International Nuclear Information System (INIS)

    Takahashi, Minoru; Momozaki, Yoichi

    2000-01-01

    For the reduction of a large magneto-hydrodynamic (MHD) pressure drop of a liquid metal single-phase flow, a liquid metal two-phase flow cooling system has been proposed. As a fundamental study, MHD pressure drops and heat transfer characteristics of a mercury single-phase flow and an air-mercury two-phase flow were experimentally investigated. A strong transverse magnetic field relevant to the fusion reactor conditions was applied to the mercury single-phase flow and the air-mercury two-phase flow in a helically coiled tube that was inserted in the vertical bore of a solenoidal superconducting magnet. It was found that MHD pressure drops of a mercury single-phase flow in the helically coiled tube were nearly equal to those in a straight tube. The Nusselt number at an outside wall was higher than that at an inside wall both in the mercury single-phase flow in the absence and presence of a magnetic field. The Nusselt number of the mercury single-phase flow decreased, increased and again decreased with an increase in the magnetic flux density. MHD pressure drops did not decrease appreciably by injecting air into a mercury flow and changing the mercury flow into the air-mercury two-phase flow. Remarkable heat transfer enhancement did not appear by the air injection. The injection of air into the mercury flow enhanced heat transfer in the ranges of high mercury flow rate and low magnetic flux density, possibly due to the agitation effect of air bubbles. The air injection deteriorated heat transfer in the range of low mercury flow rates possibly because of the occupation of air near heating wall