Promoting Systemic Change through the ACA Advocacy Competencies

Science.gov (United States)

Toporek, Rebecca L.; Lewis, Judith A.; Crethar, Hugh C.

2009-01-01

In 2003, the American Counseling Association (ACA) adopted the ACA Advocacy Competencies (J. A. Lewis, M. S. Arnold, R. House, & R. L. Toporek, 2002) to provide guidance to counselors and acknowledge advocacy as an ethical aspect of service to clients. This article provides a foundation for this special section by sharing a historical perspective…

Control biológico de ácaros Tetranychidae

Directory of Open Access Journals (Sweden)

Acosta Gómez Alfredo

1992-12-01

Full Text Available En este articulo, se presenta información publicada e inédita y, también, se realiza una revisión bibliográfica exhaustiva de los enemigos naturales de T. cinnabarinus y T. urticae, tanto a nivel mundial, como a nivel nacional, con el propósito de despertar el interés e informar sobre las bondades del control
biológico de los ácaros Tetranychidae y, en los casos donde es posible, se proporciona alguna información correspondiente a su efectividad. Posteriormente, se plantea una discusión resumida y se sugieren algunas propuestas de comportamiento estratégico o de utilidad potencial que podrían ser adoptadas por los profesionales comprometidos o
responsables de los cultivos de flores para promover
la ampliación del uso de enemigos naturales de los ácaros y utilizar, entre otros, métodos o estrategias biológicas, culturales o flsicas, que ayuden a disminuir la frecuencia del uso de agroquímicos y, así, conservar un ambiente menos contaminado y menos perjudicial para la humanidad del futuro.

RI/MOM and RI/SMOM renormalization of overlap quark bilinears on domain wall fermion configurations

Science.gov (United States)

Bi, Yujiang; Cai, Hao; Chen, Ying; Gong, Ming; Liu, Keh-Fei; Liu, Zhaofeng; Yang, Yi-Bo; χ QCD Collaboration

2018-05-01

Renormalization constants (RCs) of overlap quark bilinear operators on 2 +1 -flavor domain wall fermion configurations are calculated by using the RI/MOM and RI/SMOM schemes. The scale independent RC for the axial vector current is computed by using a Ward identity. Then the RCs for the quark field and the vector, tensor, scalar, and pseudoscalar operators are calculated in both the RI/MOM and RI/SMOM schemes. The RCs are converted to the MS ¯ scheme and we compare the numerical results from using the two intermediate schemes. The lattice size is 4 83×96 and the inverse spacing 1 /a =1.730 (4 ) GeV .

Comparative Analysis of ACAS-Xu and DAIDALUS Detect-and-Avoid Systems

Science.gov (United States)

Davies, Jason T.; Wu, Minghong G.

2018-01-01

The Detect and Avoid (DAA) capability of a recent version (Run 3) of the Airborne Collision Avoidance System-Xu (ACAS-Xu) is measured against that of the Detect and AvoID Alerting Logic for Unmanned Systems (DAIDALUS), a reference algorithm for the Phase 1 Minimum Operational Performance Standards (MOPS) for DAA. This comparative analysis of the two systems' alerting and horizontal guidance outcomes is conducted through the lens of the Detect and Avoid mission using flight data of scripted encounters from a recent flight test. Results indicate comparable timelines and outcomes between ACAS-Xu's Remain Well Clear alert and guidance and DAIDALUS's corrective alert and guidance, although ACAS-Xu's guidance appears to be more conservative. ACAS-Xu's Collision Avoidance alert and guidance occurs later than DAIDALUS's warning alert and guidance, and overlaps with DAIDALUS's timeline of maneuver to remain Well Clear. Interesting discrepancies between ACAS-Xu's directive guidance and DAIDALUS's "Regain Well Clear" guidance occur in some scenarios.

RI management by personal computer

International Nuclear Information System (INIS)

Ono, Isamu; Hiyoshi, Katsunori; Ono, Kazuhiko; Morimitsu, Wataru

1983-01-01

For RI-handling facilities up to medium scale, it has been studied whether a personal computer is applicable to the practical management of radioisotopes. In the present system, the number of writing in mini floppy disks is 1280 articles per diskette, which is the sufficient capacity for a storage medium for one year in variety of books. The correction of radioactivity decay as well as various totalizations can be made easily, so that the state of RI storage and use for the whole RI-handling facility can be grasped. Further, by the improvement of the output formats, the transfer to the books as obligated to write is possible. From the above reason, a personal computer is practically applicable with the management system and also leads to labor saving in RI management personnel. (Mori, K.)

RiArsB and RiMT-11: Two novel genes induced by arsenate in arbuscular mycorrhiza.

Science.gov (United States)

Maldonado-Mendoza, Ignacio E; Harrison, Maria J

Plants associated with arbuscular mycorrhizal fungi (AMF) increase their tolerance to arsenic-polluted soils. This study aims to investigate the genes involved in the AMF molecular response to arsenic pollution. Genes encoding proteins involved in arsenic metabolism were identified and their expression assessed by PCR or RT-qPCR. The As-inducible gene GiArsA (R. irregularis ABC ATPase component of the ArsAB arsenite efflux pump) and two new genes, an arsenate/arsenite permease component of ArsAB (RiArsB) and a methyltransferase type 11 (RiMT-11) were induced when arsenate was added to two-compartment in vitro monoxenic cultures of R. irregularis-transformed carrot roots. RiArsB and RiMT-11 expression in extraradical hyphae in response to arsenate displayed maximum induction 4-6 h after addition of 350 μM arsenate. Their expression was also detected in colonized root tissues grown in pots, or in the root-fungus compartment of two-compartment in vitro systems. We used a Medicago truncatula double mutant (mtpt4/mtpt8) to demonstrate that RiMT-11 and RiArsB transcripts accumulate in response to the addition of arsenate but not in response to phosphate. These results suggest that these genes respond to arsenate addition regardless of non-functional Pi symbiotic transport, and that RiMT-11 may be involved in arsenate detoxification by methylation in AMF-colonized tissues. Copyright © 2017 British Mycological Society. All rights reserved.

Use of RI-cone penetrometer in clay foundations

International Nuclear Information System (INIS)

Mimura, Mamoru; Shibata, Toru; Shrivastava, A.K.

1993-01-01

RI cone penetrometer tests are carried out at four different sites. The foundation grounds discussed here mainly consist of clayey materials. The measured results by RI cone penetrometers are shown for Kyobashi, Hachirougata, Kurihama and Kinkai Bay site. According to comparison of water content and density profiles by RI cone measurement with the conventional testing results, RI cone penetrometers are proved to be versatile tools for site investigation. Settlement assessment by RI cone penetrometer is also discussed by exemplifying the embankment at Kinkai Bay site. Elasto-vis-coplastic finite element analysis correspondingly performed strongly supports the RI cone based assessment. Repeated use of RI cone penetrometer with the advance of construction enables us to assess the consolidation process of the clay foundation. (author)

Entrenamiento físico en pacientes con insuficiencia cardíaca

Directory of Open Access Journals (Sweden)

Barbara Fletcher, RN, MN, FAAN

2012-11-01

Full Text Available La insuficiencia cardíaca constituye una prioridad esencial en el ámbito de la salud, tanto en Norteamérica como en Sud-américa, donde incluso se llega a las hospitalizaciones cuando el diagnóstico principal presenta condiciones graves. Hay una relación directamente proporcional entre prevalencia de insuficiencia cardíaca y edad. Sin embargo, la mortalidad por insuficiencia cardíaca está en declinación debido a los avances médicos, administración de medicamentos, e intervenciones no farmacológicas. Una de estas intervenciones es, el entrenamiento físico o el ejercicio, los cuales están siendo ampliamente aceptados por la comunidad médica como una opción viable en el manejo médico de pacientes con insuficiencia cardíaca permanente. Tanto los ejercicios aeróbicos como de fuerza han demostrado ser eficaces en este tipo de pacientes. Actualmente la evidencia no sólo respalda el ejercicio para mejorar o mantener la función física en pacientes con insuficiencia cardíaca, sino también la calidad de vida en general. Muchos estudios han demostrado que el ejercicio en la población mejora el carácter de las personas y el bienestar general reconocido por ellas mismas. Aunque los beneficios al miocardio producidos por el ejercicio pueden ser mínimos en pacientes con insuficiencia cardíaca, los beneficios periféricos que dan como resultado una mejor capacidad física y la conservación de la independencia son muy significativos. Basados en la evidencia científica existente en el ámbito del ejercicio y la insuficiencia cardíaca, los médicos que trabajan con esta población tienen la información necesaria para recomendar prescripciones de ejercicios. Actualmente, diversas declaraciones de puntos de vista médicos confirman el ejercicio como una modalidad segura y efectiva para pacientes con insuficiencia cardíaca.

C??lulas madre en terapia celular card??aca

OpenAIRE

Lobo Gonz??lez, Manuel

2013-01-01

La enfermedad cardiovascular, y su frecuente resultado final, el fallo card??aco del ventr??culo izquierdo, son la principal causa de morbimortalidad en los pa??ses desarrollados. La investigaci??n con c??lulas madre podr??a regenerar una variedad de c??lulas que incluye a los cardiomiocitos. Se han utilizado diferentes fuentes celulares para la terapia regenerativa card??aca, incluyendo c??lulas madre card??acas, mioblastos de m??sculo esquel??tico, c??lulas madre derivadas de la...

Cardiopatias congênitas e malformações extracardíacas

Directory of Open Access Journals (Sweden)

Rosana Cardoso M. Rosa

2013-06-01

Full Text Available OBJETIVO: Revisar a associação entre cardiopatias congênitas e malformações extracardíacas. FONTES DE DADOS: A pesquisa incluiu artigos científicos presentes nos portais Medline, Lilacs e SciELO, utilizando-se os descritores "congenital heart disease", "congenital heart defects", "congenital cardiac malformations", "extracardiac defects" e "extracardiac malformations". Foram incluídos os artigos de séries de casos que exploravam especificamente a associação entre cardiopatias congênitas e malformações extracardíacas. SÍNTESE DOS DADOS: A cardiopatia congênita é responsável por cerca de 40% dos defeitos congênitos, sendo uma das malformações mais frequentes e a de maior morbimortalidade. Malformações extracardíacas são observadas em 7 a 50% dos pacientes com cardiopatia congênita, trazendo um risco ainda maior de comorbidade e mortalidade e tornando a cirurgia cardíaca mais arriscada. Diferentes estudos têm tentado avaliar a presença de anormalidades extracardíacas em pacientes portadores de cardiopatia congênita. Dentre as alterações descritas, destacam-se aquelas do trato urinário. Contudo, não houve um estudo que tenha avaliado do mesmo modo todos os pacientes. CONCLUSÕES: Anormalidades extracardíacas são frequentes em pacientes com cardiopatia congênita, sendo que os portadores de tais alterações podem apresentar um risco maior de morbimortalidade. Consequentemente, alguns autores vêm discutindo a importância e o custo-benefício da triagem destas crianças à procura de outras malformações por meio de exames complementares.

Presence of pRI1:

DEFF Research Database (Denmark)

Migura, Lourdes Garcia; Hasman, Henrik; Jensen, Lars Bogø

2009-01-01

This study focused on the molecular characterization of a small cryptic, mobilizable plasmid (6038 bp) sequenced from an E. faecium 9631160-1 of poultry origin. Sequence analysis of pRI1 revealed seven open reading frames. pRI1 contained an IS 100% identical to ISEfa4. This insertion element...... almost identical to the repA from the pEFNP1 and pKQ10 plasmids from E. faecium was also identified. Presence of the pRI1 replication initiation gene (rep) was analyzed in a panel of 159 E. faecium isolates of human and animal origin from different European countries, of which 60 tested positive...

Advanced Connectivity Analysis (ACA): a Large Scale Functional Connectivity Data Mining Environment.

Science.gov (United States)

Chen, Rong; Nixon, Erika; Herskovits, Edward

2016-04-01

Using resting-state functional magnetic resonance imaging (rs-fMRI) to study functional connectivity is of great importance to understand normal development and function as well as a host of neurological and psychiatric disorders. Seed-based analysis is one of the most widely used rs-fMRI analysis methods. Here we describe a freely available large scale functional connectivity data mining software package called Advanced Connectivity Analysis (ACA). ACA enables large-scale seed-based analysis and brain-behavior analysis. It can seamlessly examine a large number of seed regions with minimal user input. ACA has a brain-behavior analysis component to delineate associations among imaging biomarkers and one or more behavioral variables. We demonstrate applications of ACA to rs-fMRI data sets from a study of autism.

Application of serum anticardiolipin antibody (ACA) determination with ELISA for detection of intra-uterine growth retardation (IUGR)

International Nuclear Information System (INIS)

Chen Wen; Zhong Jianhui; Shen Junnan

2005-01-01

Objective: To explore the interrelationship between presence of serum ACA and development of IUGR. Methods: Serum ACA contents were examined with ELISA in 5330 apparently normal pregnant women. The placentae in 16 pregnancies with IUGR and positive ACA were examined with immunofluorescence microscopy. Results: Among the 5330 pregnant women there were 144 with positive ACA (2.70%), in whom there were 22 IUGR cases (22/144, 15.28% ). The rate of IUGR in the remaining ACA negative women was only 1.77% (92/5186), the difference being very significant (P<0.01 ). ACA IgG was positive in 5 of the IUGR neonates, All the placental tissues examined with immunofluorescence microscopy showed positive immunoglobulin fluorescence antibody and complement discoloration. Conclusion: Positive ACA is one of the causative factors of development of IUGR and determination of ACA in pregnant women was helpful for early detection of IUGR. (authors)

Szathmári, a great documentary artist

Directory of Open Access Journals (Sweden)

Ionescu, Adrian-Silvan

2014-01-01

Full Text Available Carol Pop de Szathmári was born in Cluj, Transylvania, on 11 January 1812. His talent for painting shone out from an early age. Being a passionate traveller, Szathmári journeyed through Europe and often crossed the Carpathian Mountains to visit Wallachia and its capital, Bucharest, where he eventually settled in 1843. An accomplished landscape and portrait painter, at ease with both watercolours and oil paints, Szathmári obtained commissions from the wealthy Wallachian boyars. Szathmári kept up constant, good relations with the successive ruling princes of Wallachia for whom he painted portraits and various other compositions. By 1848, Szathmári began to experiment with photography. The outbreak of the Russian-Ottoman War in late June 1853 saw the Romanian principalities occupied by the Russian army. In April 1854, Szathmári filled a van with his cameras and glass plates and went to the Danube to document the fighting between the Russian and Turkish armies.The result of Szathmári's bravery and hard work was a photographic album. His album, containing some two hundred images, became famous due to its presentation at the 1855 Paris World's Fair and Szathmári was awarded the Second Class Medal for his work.From that time on, photography, painting and lithography were always closely connected in Szathmári's career. In 1864 he became a member of the Société Française de Photographie in Paris and in 1870 of the one in Vienna. In 1863, he was appointed Court Painter and Photographer, a position he held for the rest of his life. In that capacity, he followed his patron, Prince Carol I, on the battlefield during the Russian-Romanian-Ottoman War of 1877, which was waged south of the Danube. Alongside martial compositions and albums, Szathmári had long been attracted by folk types and produced a large series of pictures of peasants, gypsies, postillions, merchants and artisans. He toured the fairs and the crowded streets of the town in search

Jüri Talveti luulevalimik hispaania keeles

Index Scriptorium Estoniae

2003-01-01

Talvet, Jüri. Elegia Estonia y otros poemas : [luulevalimik] / tõlkinud Jüri Talvet ja Albert Lázaro Tinaut ; järelsõna Janika Kronberg. Valencia : Palmart Capitelum, 2002; Vt. ka Eesti Päevaleht, 13. jaan., lk. 16

Development of RI Target Production Technology

International Nuclear Information System (INIS)

Jeong, Do Young; Ko, Kwang Hoon; Kim, Cheol Jung; Kim, Taek Soo; Rho, Si Pyo; Park, Hyun Min; Lim, Gwon; Cha, Yong Ho; Han, Jae Min

2010-04-01

This project was accomplished with an aim of productive technical development on the 'enriched target' which is used essentially in radioisotope production. The research was advanced systematically with target production pilot system configuration and core technical development. We composed Yb-176 productive pilot system which equip the chemical purification technique of medical treatment level and proved its capability. Possibilities to separate Zn-67 by the method of using the polarizing light in principle and to separate Zn-70 by the method of using the double optical pumping in theory were also proved. RI target production technologies are recognized excessively with monopolistic techniques of part atomic energy advanced nations such as Russia and US and they are come, but we prepared the opportunity will be able to complete a full cycle of like (RI material production -> RI target production -> RI application) with this project accomplishment. When considering only the direct demand of stable isotope which is used in various industrial, we forecast with the fact that RI target markets will become larger with the approximately 5 billion dollars in 2020 and this technology will contribute in the domestic rising industry creation with high value added

Riigi äriühingu juhtorgani liige: kas ametiisik või ärijuht? / Jüri Raidla, Toomas Vaher, Kristel Urke

Index Scriptorium Estoniae

Raidla, Jüri, 1957-

2017-01-01

Riigi äriühingu põhijoontest, riigi äriühingu juhtorgani liikme kohustustest ja nõuetest juhtorgani liikmetele. Riigi äriühingute juhtorganite liikmete pidamisest ametiisikuteks korruptsioonivastase seaduse § 2 lõike 1 ja karistusseadustiku § 288 lõike 1 mõttes. Sisaldab asjakohast kohtupraktikat

Impact of ACA Health Reforms for People With Mental Health Conditions.

Science.gov (United States)

Thomas, Kathleen C; Shartzer, Adele; Kurth, Noelle K; Hall, Jean P

2018-02-01

This brief report explores the impact of health reform for people with mental illness. The Health Reform Monitoring Survey was used to examine health insurance, access to care, and employment for 1,550 people with mental health conditions pre- and postimplementation of the Affordable Care Act (ACA) and by state Medicaid expansion status. Multivariate logistic regressions with predictive margins were used. Post-ACA reforms, people with mental health conditions were less likely to be uninsured (5% versus 13%; t=-6.89, df=50, peffects were experienced in both Medicaid expansion and nonexpansion states. Findings underscore the importance of ACA improvements in the quality of health insurance coverage.

Changes in stimulus and response AC/A ratio with vision therapy in Convergence Insufficiency.

Science.gov (United States)

Singh, Neeraj Kumar; Mani, Revathy; Hussaindeen, Jameel Rizwana

To evaluate the changes in the stimulus and response Accommodative Convergence to Accommodation (AC/A) ratio following vision therapy (VT) in Convergence Insufficiency (CI). Stimulus and response AC/A ratio were measured on twenty five CI participants, pre and post 10 sessions of VT. Stimulus AC/A ratio was measured using the gradient method and response AC/A ratio was calculated using modified Thorington technique with accommodative responses measured using WAM-5500 open-field autorefractor. The gradient stimulus and response AC/A cross-link ratios were compared with thirty age matched controls. Mean age of the CI and control participants were 23.3±5.2 years and 22.7±4.2 years, respectively. The mean stimulus and response AC/A ratio for CI pre therapy was 2.2±0.72 and 6.3±2.0 PD/D that changed to 4.2±0.9 and 8.28±3.31 PD/D respectively post vision therapy and these changes were statistically significant (paired t-test; paccommodation parameters in subjects with convergence insufficiency. This represents the plasticity of the AC/A crosslink ratios that could be achieved with vision therapy in CI. Copyright © 2016 Spanish General Council of Optometry. Published by Elsevier España, S.L.U. All rights reserved.

Medical RI development plan of KOMAC

Science.gov (United States)

Kim, Kye-Ryung; Jung, Myung-Hwan; Yoon, Sang-Pil; Min, Yi-Sub; Cho, Yong-Sub

2017-12-01

Many kinds of radioisotopes (RIs) produced by the high energy (100 200 MeV) proton accelerators are developed by the foreign R&D institutes and the worldwide demands are being increased continuously. The RI production using high energy proton beam higher than 50 MeV was not considerable because of the limit of the proton beam energy from existing proton accelerator facilities in Korea before 2013. The available maximum proton energy was 50 MeV from MC-50 cyclotron of Korea Institute of Radiological and Medical Sciences (KIRAMS) at that time. After the construction of a 100 MeV high-current and high-energy proton accelerator and a new irradiation facility for the RI production in 2013 and 2016 by the Korea Multi-purpose Accelerator Complex (KOMAC) at Korea Atomic Energy Research Institute (KAERI), we can make a plan for the new RI production of Cu-67, Sr-82 and so on. In the medical application fields, the worldwide demand of Sr-82 is being increased rapidly during last several years and the domestic demand of Cu-67 is also expected to be increased in near future. And alpha-emitters, such as Ac-225 and Ra-223, are becoming attractive to the users in the medical science fields in the future. The RI development plan of KOMAC was specified recently reflecting the recent environment changes and requirements from the users. In this paper, the results and present status of RI production and R&D facilities, calculation results related to the RI production yields, and future plans is presented.

New Mandates and Imperatives in the Revised "ACA Code of Ethics"

Science.gov (United States)

Kaplan, David M.; Kocet, Michael M.; Cottone, R. Rocco; Glosoff, Harriet L.; Miranti, Judith G.; Moll, E. Christine; Bloom, John W.; Bringaze, Tammy B.; Herlihy, Barbara; Lee, Courtland C.; Tarvydas, Vilia M.

2009-01-01

The first major revision of the "ACA Code of Ethics" in a decade occurred in late 2005, with the updated edition containing important new mandates and imperatives. This article provides interviews with members of the Ethics Revision Task Force that flesh out seminal changes in the revised "ACA Code of Ethics" in the areas of confidentiality,…

Jüri Ratas : Tallinnasse rahvuspark! / Jüri Ratas ; interv. Ilmar Palli

Index Scriptorium Estoniae

Ratas, Jüri, 1978-

2005-01-01

Tallinna uus linnapea Jüri Ratas rohelisest vööndist, keskkonnakaitsest, ohtlikest veostest, teede olukorrast, linna elukeskkonnast, asotsiaalide probleemist ning kohaliku omavalitsuse ja riigi koostööst

RIKEN RI Beam Factory project

Energy Technology Data Exchange (ETDEWEB)

Yano, Yasushige; Goto, Akira; Katayama, Takeshi [Institute of Physical and Chemical Research, Wako, Saitama (Japan)

1997-03-01

The RARF proposes `RIKEN RI Beam Factory` as a next facility-expanding project. The factory makes it the primary aim to provide RI (Radioactive Isotope) beams covering over the whole atomic-mass range with the world-highest intensity in a wide energy range up to several hundreds MeV/nucleon. These RI beams are generated by the fragmentation of high-intensity heavy-ion beams. For the efficient production heavy-ion energies will be boosted up to over 100 MeV/nucleon even for very heavy ions by a K2500-MeV superconducting ring cyclotron serving as a post accelerator of the existing K540-MeV ring cyclotron. A new type of experimental installation called `MUSES` (Multi-USe Experimental Storage rings) will be constructed as well. With MUSES, various types of unique colliding experiments will become possible. (author)

Policy Activities in Europlanet 2020 RI

Science.gov (United States)

Giacomini, L.; Heward, A.; Mason, N.

2017-09-01

The Europlanet 2020 Research Infrastructure (RI) has received 9.945 million Euros from the European Commission to integrate planetary science across Europe, provide access to facilities, develop tools and build community cohesion. To help these processes and to increase engagement between our policy makers and the planetary science community, part of Europlanet 2020 RI's efforts are dedicated to building connections and organising activities for and within the European Parliament. Since September 2015, Europlanet 2020 RI has contacted all 134 Members of the European Parliament (MEPs) on the ITRE Committee. More than 20 individual briefings have been held to date with MEPS and/or their representatives. In November 2016, Europlanet 2020 RI organized a very successful exhibition in the European Parliament as part of the 8th European Innovation Summit and the STOA Annual Lecture, and a dinner debates was held in the on the 'Impact of the EU on planetary science' in April 2016. These events enable members of the Europlanet community, politicians and interested parties to come together and discuss views on topics of interest or concern to the space and planetary sectors. Efforts in recent years have led to important opportunities for our community to feed into reporting and consultative processes. In this talk we will discuss the results achieved in the last two years of activities and the next steps foreseen by Europlanet 2020 RI.

76 FR 41263 - Notice of Intent To Award Affordable Care Act (ACA) Funding, EH10-1004

Science.gov (United States)

2011-07-13

... $125,000.00 in ACA funding will be awarded to the grantee for network expansion and enhancement... Intent To Award Affordable Care Act (ACA) Funding, EH10-1004 Notice of Intent to award Affordable Care Act (ACA) funding to National Association for Public Health Statistics and Information Systems...

Application of RI-counting method for posttraumatic CSF rhinorrhea

International Nuclear Information System (INIS)

Itoh, Takahiko; Terai, Yoshinori; Fujimoto, Shunichiro; Kawauchi, Masamitsu.

1987-01-01

Numerous techniques and procedures have been reported for the evaluation of CSF fistulas. Especially metrizamide CT cisternography and radioisotope (RI) cisternography have been reported to be reliable for localizing the site of CSF leakage, however, it has been difficult to diagnose the existence and the site of CSF leakages in some cases. RI-counting method, measuring RI-count of intranasal cotton pledgets after the intrathecal injection of RI ( 111 In-DTPA) is thought to be the most reliable method for detecting the presence of CSF leakage in these cases. We used six cotton pledgets which were inserted into upper, middle, and lower meatuses on both side. Because the site of pledgets with ghest RI-count has anatomical relationship to the opening of the paranasal sinus, we can surmise the leakage of dural defect and CSF leakage. RI counting method was applied to two patients in whom it was difficult to diagnose the presence of CSF leakage with other procedures. The patients were free in position for four hours after the intrathecal injection of RI, and in the prone position for 30 minutes before RI-counting of intranasal cotton pledgets. After measuring the RI-counts of six pledgets, the counts were compared with each other. The cotton pledget inserted into left middle meatus showed the highest count in both cases. From this result and finding of conventional skull tomography we speculated the site of CSF leakage to be frontal sinus or ethmoid sinus. Operation demonstrated the opening of dura into the frontal sinus in one case, and ethmoid sinus in another case. As mentioned above, RI-counting method has the advantages of detecting the existence and the site of CSF leakage. (author)

76 FR 41262 - Notice of Intent To Award Affordable Care Act (ACA) Funding, EH11-1103

Science.gov (United States)

2011-07-13

...,000 in ACA funding will be awarded to the grantees for network expansion and enhancement. Funding is... Intent To Award Affordable Care Act (ACA) Funding, EH11-1103 Notice of Intent to award Affordable Care Act (ACA) funding to seventeen states and local health departments to develop and implement tracking...

76 FR 41261 - Notice of Intent To Award Affordable Care Act (ACA) Funding, EH10-1003

Science.gov (United States)

2011-07-13

...): 93.070. Approximately $124,995.00 in ACA funding will be awarded to the grantee for network expansion... Intent To Award Affordable Care Act (ACA) Funding, EH10-1003 Notice of Intent to award Affordable Care Act (ACA) funding to National Association for Health Data Organizations (NAHDO) to continue with the...

Spallation RI beam facility and heavy element nuclear chemistry

Energy Technology Data Exchange (ETDEWEB)

Nagame, Yuichiro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1997-11-01

An outline of the spallation RI (Radioactive Ion) beam facility is presented. Neutron-rich nuclides are produced in the reaction of high intensity (10-1000 {mu}A) protons with energy of 1.5 GeV and an uranium carbide target. Produced nuclides are ionized in an isotope separator on-line (ISOL) and accelerated by the JAERI tandem and the booster linac. Current progress and a future project on the development of the RI beam facility are given. Studies of transactinide elements, including the synthesis of superheavy elements, nuclear structure far from stability, and RI-probed material science are planned with RI beams. An outlook of the transactinide nuclear chemistry studies using neutron-rich RI beams is described. (author)

Combining native MS approaches to decipher archaeal box H/ACA ribonucleoprotein particle structure and activity.

Science.gov (United States)

Saliou, Jean-Michel; Manival, Xavier; Tillault, Anne-Sophie; Atmanene, Cédric; Bobo, Claude; Branlant, Christiane; Van Dorsselaer, Alain; Charpentier, Bruno; Cianférani, Sarah

2015-08-01

Site-specific isomerization of uridines into pseudouridines in RNAs is catalyzed either by stand-alone enzymes or by box H/ACA ribonucleoprotein particles (sno/sRNPs). The archaeal box H/ACA sRNPs are five-component complexes that consist of a guide RNA and the aCBF5, aNOP10, L7Ae, and aGAR1 proteins. In this study, we performed pairwise incubations of individual constituents of archaeal box H/ACA sRNPs and analyzed their interactions by native MS to build a 2D-connectivity map of direct binders. We describe the use of native MS in combination with ion mobility-MS to monitor the in vitro assembly of the active H/ACA sRNP particle. Real-time native MS was used to monitor how box H/ACA particle functions in multiple-turnover conditions. Native MS also unambiguously revealed that a substrate RNA containing 5-fluorouridine (f(5) U) was hydrolyzed into 5-fluoro-6-hydroxy-pseudouridine (f(5) ho(6) Ψ). In terms of enzymatic mechanism, box H/ACA sRNP was shown to catalyze the pseudouridylation of a first RNA substrate, then to release the RNA product (S22 f(5) ho(6) ψ) from the RNP enzyme and reload a new substrate RNA molecule. Altogether, our native MS-based approaches provide relevant new information about the potential assembly process and catalytic mechanism of box H/ACA RNPs. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Nooruslik kaupmeheemand kavatseb äri laiendada / Hille Tänavsuu

Index Scriptorium Estoniae

Tänavsuu, Hille, 1941-2014

2006-01-01

Vt. ka Postimees : na russkom jazõke 23. märts lk. 8. Tallinnas Vana-Kalamaja tänaval paikneva Alma Äri omanik Alma Sooäär avas oma esimese poe enam kui 15 aastat tagasi Nõmmel, praegu plaanib poeomanik majapidamistarvete äri laiendamist. Kaart: Alma Äri

Decontamination manual of RI handling laboratory

International Nuclear Information System (INIS)

Wadachi, Yoshiki

2004-01-01

Based on experiences in Japan Atomic Energy Research Institute (JAERI), the essential and practical knowledge of radioactive contamination and its decontamination, and the method and procedure of floor decontamination are described for researcher and managing person in charge of handling radioisotopes (RI) in RI handling laboratories. Essential knowledge concerns the uniqueness of solid surface contamination derived from RI half lives and quantities, surface contamination density limit, and mode/mechanism of contamination. The principle of decontamination is a single conduct with recognition of chemical form of the RI under use. As the practical knowledge, there are physical and chemical methods of solid surface decontamination. The latter involves use of inorganic acids, chelaters and surfactants. Removal and replacement of contaminated solid like floor material are often effective. Distribution mapping of surface contamination can be done by measuring the radioactivity in possibly contaminated areas, and is useful for planning of effective decontamination. Floor surface decontamination is for the partial and spread areas of the floor. It is essential to conduct the decontamination with reagent from the highly to less contaminated areas. Skin decontamination with either neutral detergent or titanium oxide is also described. (N.I.)

Tüüri vioolakontserdi esiettekanne

Index Scriptorium Estoniae

2008-01-01

24. okt. toovad Taanis Sonderborgis maailmaesiettekandele Erkki-Sven Tüüri Vioolakontserdi "Illuminatio" norra vioolamängija Lars Anders Tomter ja Lõuna- Jüütimaa Sümfooniaorkester, mida juhatab Vladimir Ziva. Evelyn Glennie ja New Jersey Sümfooniaorkester Neeme Järvi juhatusel esitavad 10. okt. USAs Newarkis ja 12. okt. New Brunswickis Tüüri 4. sümfoonia "Magma". Sellega seoses esineb Tüür loengutega oma loomingust järgmistes kõrgkoolides: New York Univerdity, Juilliard Scool of Music, Princeton University ja Montclair State University

Improving Forecast Skill by Assimilation of AIRS Cloud Cleared Radiances RiCC

Science.gov (United States)

Susskind, Joel; Rosenberg, Robert I.; Iredell, Lena

2015-01-01

ECMWF, NCEP, and GMAO routinely assimilate radiosonde and other in-situ observations along with satellite IR and MW Sounder radiance observations. NCEP and GMAO use the NCEP GSI Data Assimilation System (DAS).GSI DAS assimilates AIRS, CrIS, IASI channel radiances Ri on a channel-by-channel, case-by-case basis, only for those channels i thought to be unaffected by cloud cover. This test excludes Ri for most tropospheric sounding channels under partial cloud cover conditions. AIRS Version-6 RiCC is a derived quantity representative of what AIRS channel i would have seen if the AIRS FOR were cloud free. All values of RiCC have case-by-case error estimates RiCC associated with them. Our experiments present to the GSI QCd values of AIRS RiCC in place of AIRS Ri observations. GSI DAS assimilates only those values of RiCC it thinks are cloud free. This potentially allows for better coverage of assimilated QCd values of RiCC as compared to Ri.

First impressions: geographic variation in media messages during the first phase of ACA implementation.

Science.gov (United States)

Gollust, Sarah E; Barry, Colleen L; Niederdeppe, Jeff; Baum, Laura; Fowler, Erika Franklin

2014-12-01

Many Americans will learn about the implementation of the Patient Protection and Affordable Care Act (ACA) through the mass media. We examined geographic variation in the volume and content of mass media during the initial two-week rollout of the new health insurance marketplaces in October 2013 across 210 US media markets, using data from the Wesleyan Media Project. We found substantial geographic variation in the volume and tone of insurance product advertisements, political advertisements, and news coverage of the ACA marketplaces. News coverage of the ACA airing in media markets located in states operating federal or partnership marketplaces was more negative than coverage airing in markets located in states running their own marketplaces. Intrastate variation in media volume and content was also substantial and appears distinguishable from the local political climate. Variation in exposure to media messages likely affects public sentiment regarding the ACA and could contribute to geographic differences in insurance enrollment and public perceptions of US health care options. Researchers and policy makers evaluating the implementation of the ACA-and insurance enrollment in the marketplaces in particular-should consider addressing media influences. Copyright © 2014 by Duke University Press.

Engenharia de tecidos: válvulas cardíacas

OpenAIRE

Alves, Ana Rita Carvalho

2013-01-01

Dissertação de mestrado em Biotecnologia Farmacêutica, apresentada à Universidade de Coimbra. As doenças cardiovasculares são uma fonte de preocupação dado que são responsáveis por cerca de 30% da mortalidade a nível global. Uma das causas para esta tão elevada percentagem é a disfunção das válvulas cardíacas (aórtica, pulmonar, mitral e tricúspide). O funcionamento fisiológico normal das válvulas cardíacas é responsável pela unidirecionalidade do fluxo de sangue através das...

75 FR 15343 - Regulated Navigation Area: Narragansett Bay, RI and Mount Hope Bay, RI and MA, Including the...

Science.gov (United States)

2010-03-29

...: Narragansett Bay, RI and Mount Hope Bay, RI and MA, Including the Providence River and Taunton River AGENCY... River and Mount Hope Bay in the vicinity of the two Brightman Street bridges have not been adopted and... Island and Mt. Hope Bay, MA.'' The notice was prompted primarily by two events: (1) The U.S. Army Corps...

Estrategias en la prevención de la insuficiencia cardíaca

Directory of Open Access Journals (Sweden)

Vukasovig R. José Luis, MD, FACC

2012-11-01

Full Text Available Aproximadamente 1 a 2% de la población adulta tiene insuficiencia cardíaca, llegando a valores sobre el 10% en mayores de 70 años de edad. Una adecuada estrategia en la prevención de la Insuficiencia Cardíaca implica tener un manejo precoz en aquellas etiologías que la producen tales como: hipertensión arterial, enfermedad coronaria, valvulopatías y miocardiopatías. La hipertensión arterial es la primera causa de insuficiencia cardíaca en Chile y se expresa principalmente a través de hipertrofia ventricular izquierda y disfunción diastólica. La enfermedad coronaria genera insuficiencia cardíaca por medio de infarto al miocardio y la isquemia miocárdica sostenida (tejido hibernado, para evitar el compromiso ventricular deben controlarse rigurosamente los factores de riesgo de enfermedad coronaria. En caso de presentarse una obstrucción coronaria aguda se debe reestablecer el flujo coronario a la brevedad para disminuir la necrosis de miocitos. Actualmente las valvulopatías están siendo intervenidas cada vez más precozmente con el fin de evitar la remodelación ventricular patológica irreversible. En relación a las miocardiopatías se debe enfatizar en la necesidad de una detección precoz de la toxicidad por drogas antineoplásicas (ej antraciclinas, del mismo modo debemos preocuparnos de factores emergentes que conducen a insuficiencia cardíaca, ejemplo obesidad.

Changes in stimulus and response AC/A ratio with vision therapy in Convergence Insufficiency

Directory of Open Access Journals (Sweden)

Neeraj Kumar Singh

2017-07-01

Conclusions: Stimulus and response AC/A ratio increased following VT, accompanied by clinically significant changes in vergence and accommodation parameters in subjects with convergence insufficiency. This represents the plasticity of the AC/A crosslink ratios that could be achieved with vision therapy in CI.

Space and Salvation in Colette's Chéri and La Fin de Chéri

Directory of Open Access Journals (Sweden)

Ann Leone Philbrick

1984-01-01

Full Text Available Colette's critics often seem to dismiss all but her autobiographical creatures as whimsical and inarticulate. Her characters are frequently less eloquent than the spaces they create and inhabit; this observation offers an approach to Chéri and La Fin de Chéri that invites us to read them as two of Colette's most ambitious and authentic works. Here are stories of compromises with the containers of one's life and identity: streets, salons, boudoirs, and, ultimately, the body. Indeed, the self and its containers function symbiotically. Chéri makes no effort to direct this relationship, and kills himself when the world finally seems inscrutable and formless; his older mistress, Léa, responds joyfully—or with melancholic respect—to the surfaces and limits of her world. We are left with a harsher insight into Colette's vision than we are accustomed to. She suggests that survival lies not in the endless definition of one's place in the world, but in its recognition and a loving, even fearing, homage.

A search for H/ACA snoRNAs in yeast using MFE secondary structure prediction.

Science.gov (United States)

Edvardsson, Sverker; Gardner, Paul P; Poole, Anthony M; Hendy, Michael D; Penny, David; Moulton, Vincent

2003-05-01

Noncoding RNA genes produce functional RNA molecules rather than coding for proteins. One such family is the H/ACA snoRNAs. Unlike the related C/D snoRNAs these have resisted automated detection to date. We develop an algorithm to screen the yeast genome for novel H/ACA snoRNAs. To achieve this, we introduce some new methods for facilitating the search for noncoding RNAs in genomic sequences which are based on properties of predicted minimum free-energy (MFE) secondary structures. The algorithm has been implemented and can be generalized to enable screening of other eukaryote genomes. We find that use of primary sequence alone is insufficient for identifying novel H/ACA snoRNAs. Only the use of secondary structure filters reduces the number of candidates to a manageable size. From genomic context, we identify three strong H/ACA snoRNA candidates. These together with a further 47 candidates obtained by our analysis are being experimentally screened.

Jüri Talveti luulepiiriületamised / Jüri Talvet ; intervjueerinud Rein Veidemann

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

2010-01-01

IX Moncayo luulefestivalist Aragoonias 10. aug. 2010 ja Jüri Talveti luule tõlgetest: Del sueno, de la nieve / tõlkinud Albert Lázaro Tinaut (Olifante, 2010) ; Of Snow, of Soul / tõlkinud H. L. Hix (Guernica, 2010)

76 FR 50770 - Submission for Review: Financial Resources Questionnaire (RI 34-1, RI 34-17, and RI 34-18) and...

Science.gov (United States)

2011-08-16

... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: Financial Resources Questionnaire (RI 34- 1...) 3206-0167, Financial Resources Questionnaire and Notice of Amount Due Because of Annuity Overpayment... techniques or other forms of information technology, e.g., permitting electronic submissions of responses...

A novel calmodulin-regulated Ca2+-ATPase (ACA2) from Arabidopsis with an N-terminal autoinhibitory domain

Science.gov (United States)

Harper, J. F.; Hong, B.; Hwang, I.; Guo, H. Q.; Stoddard, R.; Huang, J. F.; Palmgren, M. G.; Sze, H.; Evans, M. L. (Principal Investigator)

1998-01-01

To study transporters involved in regulating intracellular Ca2+, we isolated a full-length cDNA encoding a Ca2+-ATPase from a model plant, Arabidopsis, and named it ACA2 (Arabidopsis Ca2+-ATPase, isoform 2). ACA2p is most similar to a "plasma membrane-type" Ca2+-ATPase, but is smaller (110 kDa), contains a unique N-terminal domain, and is missing a long C-terminal calmodulin-binding regulatory domain. In addition, ACA2p is localized to an endomembrane system and not the plasma membrane, as shown by aqueous-two phase fractionation of microsomal membranes. ACA2p was expressed in yeast as both a full-length protein (ACA2-1p) and an N-terminal truncation mutant (ACA2-2p; Delta residues 2-80). Only the truncation mutant restored the growth on Ca2+-depleted medium of a yeast mutant defective in both endogenous Ca2+ pumps, PMR1 and PMC1. Although basal Ca2+-ATPase activity of the full-length protein was low, it was stimulated 5-fold by calmodulin (50% activation around 30 nM). In contrast, the truncated pump was fully active and insensitive to calmodulin. A calmodulin-binding sequence was identified within the first 36 residues of the N-terminal domain, as shown by calmodulin gel overlays on fusion proteins. Thus, ACA2 encodes a novel calmodulin-regulated Ca2+-ATPase distinguished by a unique N-terminal regulatory domain and a non-plasma membrane localization.

Consideraciones nutricionales en el paciente con falla cardíaca crónica

Directory of Open Access Journals (Sweden)

Mario A. Hernández, MD

2012-11-01

Full Text Available La insuficiencia cardíaca congestiva es un síndrome caracterizado por reducción del gasto cardíaco, aumento de las presiones de llenado ventricular y activación neuroendocrina, que lleva a un proceso de fibrosis y apoptosis de la célula cardíaca. Afecta alrededor de 23 millones de personas en el mundo y confiere un pésimo pronóstico una vez se diagnostica. Desde el punto de vista fisiopatológico, la relación entre citocinas pro-inflamatorias, activación neuro-hormonal y alteraciones gastrointestinales conduce a un estado denominado caquexia cardíaca, determinado por pérdida acelerada de peso, fatiga, reducción de la fuerza muscular, anorexia y disminución de la calidad de vida; este proceso es capaz de deteriorar aún más el pronóstico vital de estos pacientes. En las últimas dos décadas, se han realizado avances en el tratamiento farmacológico y eléctrico de la falla cardíaca; sin embargo los estudios en el campo no farmacológico son pocos, en especial en el aspecto nutricional, y así mismo son escasas las recomendaciones de las guías internacionales acerca del tema. En estudios pequeños, una aproximación nutricional ha demostrado impactar de manera positiva la calidad de vida y tolerancia al ejercicio, si bien se requieren grandes estudios para determinar la viabilidad de este abordaje en pacientes con falla cardíaca.

Effective management of regulator RI/FS comments

International Nuclear Information System (INIS)

Wolinsky, S.M.; Lojek, D.; George, R.D.; Houser, S.M.; Strimbu, M.J.

1995-01-01

This paper describes a successful strategy that facilitates regulatory approval of CERCLA documents required by compliance agreement and CERCLA, based on the experience of Operable Unit 1, Waste Storage Area, of the Fernald Environmental Management Project (FEMP). This strategy, which has become the site standard at the FEMP, was instrumental in obtaining regulator approval of the OU1 RI and FS, and early approval of the Record of Decision during a very tight compliance agreement-driven schedule. This strategy can be applied at any DOE Superfund site, especially where there is need to recover lost schedule, an incentive to meet milestones early, a need to improve the relationship between the DOE and the regulators, or where the regulatory agencies have historically provided a large volume of comments on CERCLA documents. The strategy focuses on early identification and resolution of issues relating to draft RI/FS documents, as raised in regulatory agency review comments. This pro-active strategy has the potential for schedule and cost savings, as well as for improved communication between DOE and the regulators. The strategy includes preparation of a separate comment response document, integration of comment responses with RI/FS documents, development of a database of agency comments and their resolution, and sharing lessons learned with preparers of subsequent RI/FS documents. The paper provides background on the FEMP and describes the FEMP comment response strategy; DOE and regulator interface; the Sitewide Comment Database; networked electronic file management; the process for classifying, analyzing, and responding to comments; integration with base RI/FS documents; and a conclusion

Effective management of regulator RI/FS comments

Energy Technology Data Exchange (ETDEWEB)

Wolinsky, S.M.; Lojek, D.; George, R.D.; Houser, S.M.; Strimbu, M.J.

1995-12-31

This paper describes a successful strategy that facilitates regulatory approval of CERCLA documents required by compliance agreement and CERCLA, based on the experience of Operable Unit 1, Waste Storage Area, of the Fernald Environmental Management Project (FEMP). This strategy, which has become the site standard at the FEMP, was instrumental in obtaining regulator approval of the OU1 RI and FS, and early approval of the Record of Decision during a very tight compliance agreement-driven schedule. This strategy can be applied at any DOE Superfund site, especially where there is need to recover lost schedule, an incentive to meet milestones early, a need to improve the relationship between the DOE and the regulators, or where the regulatory agencies have historically provided a large volume of comments on CERCLA documents. The strategy focuses on early identification and resolution of issues relating to draft RI/FS documents, as raised in regulatory agency review comments. This pro-active strategy has the potential for schedule and cost savings, as well as for improved communication between DOE and the regulators. The strategy includes preparation of a separate comment response document, integration of comment responses with RI/FS documents, development of a database of agency comments and their resolution, and sharing lessons learned with preparers of subsequent RI/FS documents. The paper provides background on the FEMP and describes the FEMP comment response strategy; DOE and regulator interface; the Sitewide Comment Database; networked electronic file management; the process for classifying, analyzing, and responding to comments; integration with base RI/FS documents; and a conclusion.

Arabidopsis ACA7, encoding a putative auto-regulated Ca(2+)-ATPase, is required for normal pollen development.

Science.gov (United States)

Lucca, Noel; León, Gabriel

2012-04-01

Microgametogenesis is a complex process that involves numerous well-coordinated cell activities, ending with the production of pollen grains. Pollen development has been studied at the cytological level in Arabidopsis and other plant species, where its temporal time course has been defined. However, the molecular mechanism underlying this process is still unclear, since a relative small number of genes and/or processes have been identified as essential for pollen development. We have designed a methodology to select candidate genes for functional analysis, based on transcriptomic data obtained from different stages of pollen development. From our analyses, we selected At2g22950 as a candidate gene; this gene encodes a protein belonging to the auto-regulated Ca(2+)-ATPase family, ACA7. Microarray data indicate that ACA7 is expressed exclusively in developing pollen grains, with the highest level of mRNA at the time of the second pollen mitosis. Our RT-PCR experiments showed that ACA7 mRNA is detected exclusively in developing flowers. Confocal microscopy experiments showed a plasma membrane localization for the recombinant GFP:ACA7 protein. We identified two different insertional mutant lines, aca7-1 and aca7-2; plants from both mutant lines displayed a normal vegetative development but showed large amounts of dead pollen grains in mature flowers assayed by Alexander's staining. Histological analysis indicated that abnormalities are detected after the first pollen mitosis and we found a strong correlation between ACA7 mRNA accumulation and the severity of the phenotype. Our results indicate that ACA7 is a plasma membrane protein that has an important role during pollen development, possibly through regulation of Ca(2+) homeostasis. © Springer-Verlag 2011

La Enfermedad Celíaca

OpenAIRE

Cueto Rua, Eduardo Ángel; Nanfito, Gabriela; Guzmán, Luciana

2006-01-01

La Enfermedad Celíaca (EC) es la intolerancia alimentaria de orden genético más frecuente de la especie humana. En nuestro Servicio de Gastroenterología hemos diagnosticado más de 1900 casos en los últimos 34 años, y 92 y 73 nuevos casos en los años 2004 y 2005, respectivamente. La EC es el resultado de la interacción entre factores genéticos (constante absoluta) expresados en la mucosa intestinal y la respuesta i...

RI beam factory project at RIKEN

CERN Document Server

Motobayashi, T

2003-01-01

Construction of the RI beam factory project in the first phase has started. The aim of the project is to provide intense radio-isotopes (RI) beams at energies of several hundred MeV/nucleon in a wide range of atomic masses. These beams will be produced by the projectile fragmentation of primary beams accelerated by a cascade of the existing ring cyclotron and a series of new ring cyclotrons. Improvements of the existing facility made for the new cyclotron complex have extended the energy range of available beams, which already opened new domains of study.

Doença celíaca é super-representada em pacientes com constipação

Directory of Open Access Journals (Sweden)

Rolf A. A. Pelleboer

2012-04-01

Full Text Available OBJETIVO: Tem sido sugerido que pacientes com constipação sejam triados para doença celíaca. Da mesma forma, recomenda-se a investigação desses pacientes para hipotiroidismo e hipercalcemia. Contudo, nenhuma evidência para essas recomendações está disponível até o momento. Assim, propusemos-nos determinar a prevalência de doença celíaca, hipotiroidismo e hipercalcemia em crianças com constipação. MÉTODOS: Estudo de coorte prospectivo com 370 pacientes consecutivos que preencheram os critérios de Roma III para constipação. Esses pacientes foram encaminhados por um clínico geral a um pediatra devido ao fracasso no tratamento com laxantes. RESULTADOS: A biópsia comprovou doença celíaca em sete desses pacientes. Isso é significativamente mais alto (p < 0,001 do que a prevalência de 1:198 de doença celíaca nos Países Baixos. Dois pacientes tinham tiroidite autoimune. Nenhum paciente tinha hipercalcemia. CONCLUSÕES: Conclui-se que a doença celíaca é significativamente super-representada em pacientes com constipação encaminhados por um clínico geral a um pediatra devido ao fracasso no tratamento com laxantes. Todos esses pacientes devem, portanto, ser triados para doença celíaca.

RI beam factory and its expected pioneering work

International Nuclear Information System (INIS)

Yano, Yasushige

1996-01-01

The RARF (RIKEN Accelerator Research Facility) houses an intermediate-energy heavy-ion accelerator complex consisting of a K540-MeV ring cyclotron (RRC) and a couple of different types of the injectors: a variable-frequency heavy-ion linac and a K70-MeV AVF cyclotron. One of remarkable features of this facility is capability of supplying light-atomic-mass RI (radioactive isotope) beams with the world-highest level of intensities by the projectile-fragment separator, RIPS. In these several years nuclear physicists have opened up a quite new and fascinating heavy-ion science exploiting such RI beams. In order to further promote this new science, the RARF proposes 'RIKEN RI Beam Factory' as a next facility-expanding project. The factory takes the aim at providing RI beams covering over the whole atomic-mass range with the world-highest intensities in a wide energy range up to several hundreds MeV/nucleon. To realize the 'Factory' a K2500-MeV superconducting ring cyclotron will be built which boosts output energies of the RRC beams up to 400 MeV/nucleon for light ions and up to 100 MeV/nucleon for very heavy ions, preserving their beam intensities (typically 1 pμA). RI beams will be generated by the projectile fragmentation. A new type of experimental installation called 'MUSES' (Multi-USe Experimental Storage rings) will also be constructed. It consists of an accumulator-cooler ring, booster synchrotron ring and double storage rings. With MUSES, various types of unique colliding experiments will become possible: ion-ion merging or head-on collisions; collisions of either electrons or X-rays with ion (stable isotope or RI) beams; internal target experiments; and atomic and molecular physics with cooler electron beams. (author)

Domik Petra / Jüri Kuuskemaa

Index Scriptorium Estoniae

Kuuskemaa, Jüri, 1942-

2006-01-01

Kunstiajaloolane Jüri Kuuskemaa tutvustab Peeter I majamuuseumi Kadriorus. Maja ajaloost, sisustusest (mööbel, kunstiesemed). Keldriruumis eksponeeritud Salomon Zeltrechti ja tema abiliste poolt tehtud kivibüstidest

Structure of RiVax: a recombinant ricin vaccine

International Nuclear Information System (INIS)

Legler, Patricia M.; Brey, Robert N.; Smallshaw, Joan E.; Vitetta, Ellen S.; Millard, Charles B.

2011-01-01

The X-ray crystal structure (at 2.1 Å resolution) of an immunogen under development as part of a ricin vaccine for humans is presented and structure-based analysis of the results was conducted with respect to related proteins and the known determinants for inducing or suppressing the protective immune response. RiVax is a recombinant protein that is currently under clinical development as part of a human vaccine to protect against ricin poisoning. RiVax includes ricin A-chain (RTA) residues 1–267 with two intentional amino-acid substitutions, V76M and Y80A, aimed at reducing toxicity. Here, the crystal structure of RiVax was solved to 2.1 Å resolution and it was shown that it is superposable with that of the ricin toxin A-chain from Ricinus communis with a root-mean-square deviation of 0.6 Å over 258 C α atoms. The RiVax structure is also compared with the recently determined structure of another potential ricin-vaccine immunogen, RTA 1–33/44–198 R48C/T77C. Finally, the locations and solvent-exposure of two toxin-neutralizing B-cell epitopes were examined and it was found that these epitopes are within or near regions predicted to be involved in catalysis. The results demonstrate the composition of the RiVax clinical material and will guide ongoing protein-engineering strategies to develop improved immunogens

Levosimendan: Nueva estrategia en el manejo de la falla cardíaca

OpenAIRE

González-Chon,Octavio; García López,Sandra María del Carmen; Chacón Mercado,Marco Alejandro; Arias Sánchez,Eduardo Agustín; Vega Zapata,Reyna Estela

2005-01-01

La insuficiencia cardíaca congestiva se ha considerado como un grave problema de salud. De manera tradicional, la insuficiencia cardíaca ha sido manejada con diferentes fármacos, como son los diuréticos, digital, inotrópicos del tipo de las catecolaminas y no catecolaminas; sin embargo, el manejo de los mismos, también tienen efectos secundarios en donde se incluyen la génesis de las arritmias e incluso la muerte. Un nuevo grupo de drogas recientemente ha impactado en el manejo de los pacient...

Estudo da Mecânica Cardíaca pelo Speckle Tracking

Directory of Open Access Journals (Sweden)

Maria Cristina Donadio Abduch

2014-04-01

Full Text Available Speckles, ou marcadores naturais do miocárdio, originam se da interferência construtiva e destrutiva do feixe de ultrassom que incide sobre os tecidos, podem fornecer um diagnóstico precoce das alterações miocárdicas e atuar na predição de certos eventos cardíacos. Devido à sua relativa estabilidade temporal, os speckles podem ser rastreados durante o ciclo cardíaco por software dedicados, promovendo a análise da função sistólica e diastólica. São identificados tanto pela escala de cinza da ecocardiografia 2D convencional quanto pela ecocardiografia 3D, sendo independentes do ângulo de incidência do ultrassom, permitindo assim a avaliação da mecânica cardíaca nos três planos espaciais: longitudinal, circunferencial e radial. O objetivo do presente artigo é discutir o papel e o significado da deformação cardíaca obtida por meio do speckle tracking durante a avaliação da fisiologia cardíaca, e discutir as aplicações clínicas desta tecnologia ecocardiográfica inovadora.

Tratamiento de las taquiarritmias postoperatarias en la cirugía cardíaca del adulto

OpenAIRE

Enríquez, Fernando; Jiménez, Antonio

2010-01-01

Las arritmias en el periodo postoperatorio de la cirugía cardíaca requieren, en su particular contexto, un tratamiento específico. La presente revisión expone y actualiza la evidencia científica en los diversos tratamientos de las taquiarritmias postoperatorias en la cirugía cardíaca del adulto.

Comportamento dos quimiorreflexos central e periférico na insuficiência cardíaca

Directory of Open Access Journals (Sweden)

Guilherme Veiga Guimarães

2011-02-01

Full Text Available A síndrome da insuficiência cardíaca (IC pode ser definida como via final de qualquer forma de doença cardíaca. Os reflexos cardiovasculares simpatoinibitórios como o reflexo arterial barorreceptor estão significativamente suprimidos na IC. Pacientes com IC apresentam maior ventilação para determinada carga de trabalho quando comparados a indivíduos normais. Esse fato gera baixa eficiência ventilatória e relaciona-se com maior ventilação relativa à produção de gás carbônico, que é um preditor de mau prognóstico, além de ser um fator limitante ao exercício. Há evidências de que o desequilíbrio autonômico contribua para a patogênese e a progressão da insuficiência cardíaca. Os quimiorreflexos são os principais mecanismos de controle e regulação das respostas ventilatórias às mudanças de concentração do oxigênio e gás carbônico arterial. A ativação do quimiorreflexo causa aumento da atividade simpática, frequência cardíaca, pressão arterial e volume minuto. No entanto, o aumento do volume minuto e da pressão arterial, pelo feedback negativo provocam inibição da resposta simpática à ativação do quimiorreflexo. Apesar das alterações funcionais dos reflexos, seu comportamento em condições normais e patológicas, especialmente sua contribuição para o estado simpatoexcitatório encontrado na IC, não tem sido amplamente estudado. Dessa forma, esta revisão tem por objetivo integrar os conhecimentos a respeito dos quimiorreflexos central e periférico na síndrome da insuficiência cardíaca, bem como esclarecer a influência da terapêutica medicamentosa da insuficiência cardíaca nos quimiorreflexos.

Aporte de la frecuencia cardíaca en futbolistas durante el período de competencia

Directory of Open Access Journals (Sweden)

Arnaldo A. Angelino

2009-01-01

Full Text Available ObjetivosEvaluar el comportamiento de los componentes de la curva dinámica de la frecuencia cardíaca basal, intraesfuerzo y de recuperación de acuerdo con el tiempo, la distancia y la intensidad de pruebas aeróbicas en cinta ergométrica y de campo como indicador de entrenamiento y adaptación física durante el período de competencia en jugadores de fútbol.Material y métodosSe evaluaron 108 jugadores de fútbol juvenil, masculinos y de 17 ± 2 años, con prueba aeróbica ergométrica y de campo durante el ciclo competitivo. Se realizó prueba de 2.400 metros en cinta ergométrica y Yo-Yo Test en campo (Endurance nivel 2.ResultadosEl registro continuo de frecuencia cardíaca permitió observar: 1 un registro más detallado de las modificaciones de la frecuencia cardíaca submáxima (89,4 ± 7,6 versus 83,0 ± 7,7; p < 0,05 en cinta ergométrica, 2 diferentes respuestas de frecuencia cardíaca submáxima en prueba ergométrica y de campo al primer minuto (164,0 versus 116,6; p < 0,05 y al segundo minuto (176,3 versus 123,5; p < 0,05 en relación con la frecuencia cardíaca máxima (198,6 versus 194,0; p = ns, 3 en pruebas de campo se observó un intervalo mayor de reserva de frecuencia cardíaca en relación con la capacidad de resistencia a partir del segundo minuto (25,9 versus 19,1; p < 0,05.ConclusionesEl registro comparativo de la frecuencia cardíaca durante el ciclo competitivo en jugadores de fútbol en pruebas aeróbicas ergométricas y en prueba de campo permite el análisis de indicadores de entrenamiento y adaptación física. Los indicadores de frecuencia cardíaca basal, submáxima, máxima, de recuperación e intervalo de reserva de frecuencia cardíaca permiten información de rendimiento y entrenamiento en la resistencia a diferente velocidad de desplazamiento, tiempo de permanencia y distancia en pruebas de cinta ergométrica y de campo, de gran utilidad para las pautas de entrenamiento durante el período de competencia

The RiSE climbing robot: body and leg design

Science.gov (United States)

Saunders, A.; Goldman, D. I.; Full, R. J.; Buehler, M.

2006-05-01

The RiSE robot is a biologically inspired, six legged climbing robot, designed for general mobility in scansorial (vertical walls, horizontal ledges, ground level) environments. It exhibits ground reaction forces that are similar to animal climbers and does not rely on suction, magnets or other surface-dependent specializations to achieve adhesion and shear force. We describe RiSE's body and leg design as well as its electromechanical, communications and computational infrastructure. We review design iterations that enable RiSE to climb 90° carpeted, cork covered and (a growing range of) stucco surfaces in the quasi-static regime.

Verification of Representative Sampling in RI waste

International Nuclear Information System (INIS)

Ahn, Hong Joo; Song, Byung Cheul; Sohn, Se Cheul; Song, Kyu Seok; Jee, Kwang Yong; Choi, Kwang Seop

2009-01-01

For evaluating the radionuclide inventories for RI wastes, representative sampling is one of the most important parts in the process of radiochemical assay. Sampling to characterized RI waste conditions typically has been based on judgment or convenience sampling of individual or groups. However, it is difficult to get a sample representatively among the numerous drums. In addition, RI waste drums might be classified into heterogeneous wastes because they have a content of cotton, glass, vinyl, gloves, etc. In order to get the representative samples, the sample to be analyzed must be collected from selected every drum. Considering the expense and time of analysis, however, the number of sample has to be minimized. In this study, RI waste drums were classified by the various conditions of the half-life, surface dose, acceptance date, waste form, generator, etc. A sample for radiochemical assay was obtained through mixing samples of each drum. The sample has to be prepared for radiochemical assay and although the sample should be reasonably uniform, it is rare that a completely homogeneous material is received. Every sample is shredded by a 1 ∼ 2 cm 2 diameter and a representative aliquot taken for the required analysis. For verification of representative sampling, classified every group is tested for evaluation of 'selection of representative drum in a group' and 'representative sampling in a drum'

FcepsilonRI-alpha siRNA inhibits the antigen-induced activation of mast cells.

Science.gov (United States)

Safaralizadeh, Reza; Soheili, Zahra-Soheila; Deezagi, Abdolkhaleg; Pourpak, Zahra; Samiei, Shahram; Moin, Mostafa

2009-12-01

FcepsilonRI, The high affinity receptor for IgE plays a critical role in triggering the allergic reactions. It is responsible for inducing mast cell degranulation and deliberation of allergy mediators when it is aggregated by allergen and IgE complexes. FcepsilonRI on the mast cells consists of three subunits; alpha chain directly binds IgE, beta chain and dimmer of gamma chains together mediate intracellular signaling. Cross-linking of IgE-bound FcepsilonRI on the surface of mast cells and basophils by the multivalent antigen induces release of chemical mediators. The present in vitro study was designed to investigate the effect of synthetic FcepsilonRI-alpha siRNA on the antigen-induced activation of MC/9 cells. MC/9 cells which are murine mast cells were transfected by FcepsilonRI-alpha siRNA and negative control siRNA. After 6 h, anti-DNP (Dinitrophenyl) IgE was used for the cells sensitization. Then the cells were challenged with Dinitrophenyl-Human Serum Albumin (DNP-HSA) for mast cell degranulation induction before collection of supernatants. The amount of mRNA and protein expression was measured by Real Time PCR and western blot analysis, respectively. Determination of the expression rate of FcepsilonRI-alpha on cell surface was achieved by flow cytometry. ELISA and spectrophotometry methods were used subsequently for measuring the effects of FcepsilonRI-alpha siRNA on antigen-induced histamine and beta-hexosaminidase release. FcepsilonRI-alpha siRNA treated cells showed significant decrease in FcepsilonRI-alpha mRNA and protein expression in comparison to control cells. FcepsilonRI-mediated mast cell release of beta-hexosaminidase and histamine were also inhibited. In this study it was shown that FcepsilonRI-alpha siRNA could suppress FcepsilonRI-alpha expression and inhibited degranulation and histamine release in antigen-stimulated MC/9 cells. In conclusion, knock-down of FcepsilonRI-alpha by siRNA could be a promising method for inhibition of the mast

Tratamiento de las taquiarritmias postoperatarias en la cirugía cardíaca del adulto

Directory of Open Access Journals (Sweden)

Fernando Enríquez

2010-10-01

Full Text Available Las arritmias en el periodo postoperatorio de la cirugía cardíaca requieren, en su particular contexto, un tratamiento específico. La presente revisión expone y actualiza la evidencia científica en los diversos tratamientos de las taquiarritmias postoperatorias en la cirugía cardíaca del adulto.

[Söejoonistused] / Jüri Marran

Index Scriptorium Estoniae

Marran, Jüri, 1937-

2005-01-01

Jüri Marran on hariduselt füüsik ja kunstihariduse omandanud Melanie ja Erich Arraku ateljeekoolis. Lk. 1391 (Gravitatsioon), 1440 (Valgus), 1471 (Vastastikmõju), 1486 (Massenergia), 1519 (Valguse dualism), 1555 (Aja dilatatsioon)

Kas e-äri võrdub pankrotiga / Priit Vaikmaa

Index Scriptorium Estoniae

Vaikmaa, Priit

2001-01-01

E-äride pankrotilaine aastal 2000. Firmadevaheline äri internetis - B2B (business-to-business). B2B ärikeskkondade kodulehekülgede aadressid. B2B ja e-äri lahenduste pakkujad Eestis. Diagramm: B2B e-kommertsi prognoositud käive 2004.a.

Jüri Lina kui tegelikkusele osutav Patagoonia šamaan / Jüri Lina ; intervjueerinud Ingrid Peek

Index Scriptorium Estoniae

Lina, Jüri, 1949-

2011-01-01

2.-5. juunini Tallinnas kinos Sõprus toimuva festivali "Hallo, Kosmos!" raames 2. juunil esilinastuvast Jüri Lina filmist "Täitmatu Uroboros. Massoonide salakaval taktika", tema uuringute põhjusest. Festivali "Hallo, Kosmos!" kavast

Insuficiència cardíaca i fallida renal : quan tot s'ajunta

OpenAIRE

Zamora, Elisabet

2008-01-01

Un dels problemes que coexisteixen amb la insuficiència cardíaca és la insuficiència renal. Els autors d'aquest article proposen un mètode alternatiu per poder detectar de manera més precisa la presència d'aquesta fallida renal en els pacients amb insuficiència cardíaca, ja que els mètodes habituals, basats únicament en la determinació de la creatinina en sang, són menys sensibles.

Diagnostic Validity of RI Angiocardiography in Cardiac Diseases

Energy Technology Data Exchange (ETDEWEB)

Kim, Kwan Yop; Koh, Chang Soon; Lee, Mun Ho [Seoul National University College of Medicine, Seoul (Korea, Republic of)

1972-09-15

The employment of gamma-ray scintillation camera with the use of short-lived radioisotopic pharmaceuticals, such as {sup 99m}Tc sodium pertechnetate, have enabled us to perform RI (radioisotopic) angiocardiography. Although conventional cardiac catheterization or angiocardiography using contrast media have been an important diagnostic tool, they may carry some risks or serious complications. The author investigated on RI angiocardiography in twelve normal and twenty five patients with cardiovascular diseases in an effort to evaluate its diagnostic value. The results obtained with this study are as follows; l. In normal subjects, the scintillation camera transit time of arm-to-right heart was found to be 2.1+-0.67 seconds, right heart-to-lung 1.5+-0.40 seconds and lung-to-left heart 3.5+-0.86 seconds. 2. Transformation or displacement of the heart and the great vessel are easily discriminated by RI angiocardiography. Both in the cases with tricuspid atresia and tetralogy of Fallot, ventricular septal defects are well recognized by sequential RI angiocardiography. 3. It is also helpful in determining the site and extent of obstruction, and estimating the postoperative course both in the cases with superior vena cava syndrome and pulmonary stenosis. 4. Pericarditis with effusion is readily diagnosed by RI angiocardiogram showing characteristic 'dead space' between intracardiac and intrapulmonary radioactivity. 5. It was found that the diagnostic accuracy of this study was 78.4%. It is concluded that above results obtained are useful and accurate enough for the diagnostic screening method for clinical practice.

Diagnostic Validity of RI Angiocardiography in Cardiac Diseases

International Nuclear Information System (INIS)

Kim, Kwan Yop; Koh, Chang Soon; Lee, Mun Ho

1972-01-01

The employment of gamma-ray scintillation camera with the use of short-lived radioisotopic pharmaceuticals, such as 99m Tc sodium pertechnetate, have enabled us to perform RI (radioisotopic) angiocardiography. Although conventional cardiac catheterization or angiocardiography using contrast media have been an important diagnostic tool, they may carry some risks or serious complications. The author investigated on RI angiocardiography in twelve normal and twenty five patients with cardiovascular diseases in an effort to evaluate its diagnostic value. The results obtained with this study are as follows; l. In normal subjects, the scintillation camera transit time of arm-to-right heart was found to be 2.1±0.67 seconds, right heart-to-lung 1.5±0.40 seconds and lung-to-left heart 3.5±0.86 seconds. 2. Transformation or displacement of the heart and the great vessel are easily discriminated by RI angiocardiography. Both in the cases with tricuspid atresia and tetralogy of Fallot, ventricular septal defects are well recognized by sequential RI angiocardiography. 3. It is also helpful in determining the site and extent of obstruction, and estimating the postoperative course both in the cases with superior vena cava syndrome and pulmonary stenosis. 4. Pericarditis with effusion is readily diagnosed by RI angiocardiogram showing characteristic 'dead space' between intracardiac and intrapulmonary radioactivity. 5. It was found that the diagnostic accuracy of this study was 78.4%. It is concluded that above results obtained are useful and accurate enough for the diagnostic screening method for clinical practice.

Diagnostic Validity of RI Angiocardiography in Cardiac Diseases

Energy Technology Data Exchange (ETDEWEB)

Kim, Kwan Yop; Koh, Chang Soon; Lee, Mun Ho [Seoul National University College of Medicine, Seoul (Korea, Republic of)

1972-09-15

The employment of gamma-ray scintillation camera with the use of short-lived radioisotopic pharmaceuticals, such as {sup 99m}Tc sodium pertechnetate, have enabled us to perform RI (radioisotopic) angiocardiography. Although conventional cardiac catheterization or angiocardiography using contrast media have been an important diagnostic tool, they may carry some risks or serious complications. The author investigated on RI angiocardiography in twelve normal and twenty five patients with cardiovascular diseases in an effort to evaluate its diagnostic value. The results obtained with this study are as follows; l. In normal subjects, the scintillation camera transit time of arm-to-right heart was found to be 2.1+-0.67 seconds, right heart-to-lung 1.5+-0.40 seconds and lung-to-left heart 3.5+-0.86 seconds. 2. Transformation or displacement of the heart and the great vessel are easily discriminated by RI angiocardiography. Both in the cases with tricuspid atresia and tetralogy of Fallot, ventricular septal defects are well recognized by sequential RI angiocardiography. 3. It is also helpful in determining the site and extent of obstruction, and estimating the postoperative course both in the cases with superior vena cava syndrome and pulmonary stenosis. 4. Pericarditis with effusion is readily diagnosed by RI angiocardiogram showing characteristic 'dead space' between intracardiac and intrapulmonary radioactivity. 5. It was found that the diagnostic accuracy of this study was 78.4%. It is concluded that above results obtained are useful and accurate enough for the diagnostic screening method for clinical practice.

Tratamiento de la insuficiencia cardíaca: nuevas estrategias terapéuticas

Directory of Open Access Journals (Sweden)

Jesús Herreros

2011-04-01

Full Text Available La insuficiencia cardíaca es uno de los problemas de salud de mayor relevancia por su incidencia creciente y sus repercusiones sociales, económicas y sobre todo humanas. El trasplante cardíaco es un abordaje excelente y un tratamiento consolidado para estos pacientes. Sin embargo, la desproporción entre el número de pacientes con una insuficiencia cardíaca terminal y los donantes potenciales restringe el trasplante a aquellos pacientes sin otras posibilidades de tratamiento y ha generado alternativas terapéuticas para mejorar el pronóstico y los síntomas de estos pacientes con alto riesgo. El interés creciente del estudio de la reversibilidad de varias formas de insuficiencia cardíaca terminal y la aplicación de la biología al tratamiento de estos pacientes ha inducido el desarrollo de estrategias terapéuticas, diseñadas para integrar la biología y las nuevas tecnologías médicas, para así intervenir sobre los modelos biomecánicos, moleculares y neurohormonales de la insuficiencia cardíaca. Estos tratamientos incluyen la cardiomioplastia celular, la ingeniería tisular, la cirugía de restauración del ventrículo izquierdo, la inmunoadsorción y la constricción mecánica pasiva ventricular como puente a la recuperación. La integración de estos abordajes puede ofrecer alternativas válidas al trasplante cardíaco.

DNA Nucleotide Sequence Restricted by the RI Endonuclease

Science.gov (United States)

Hedgpeth, Joe; Goodman, Howard M.; Boyer, Herbert W.

1972-01-01

The sequence of DNA base pairs adjacent to the phosphodiester bonds cleaved by the RI restriction endonuclease in unmodified DNA from coliphage λ has been determined. The 5′-terminal nucleotide labeled with 32P and oligonucleotides up to the heptamer were analyzed from a pancreatic DNase digest. The following sequence of nucleotides adjacent to the RI break made in λ DNA was deduced from these data and from the 3′-dinucleotide sequence and nearest-neighbor analysis obtained from repair synthesis with the DNA polymerase of Rous sarcoma virus [Formula: see text] The RI endonuclease cleavage of the phosphodiester bonds (indicated by arrows) generates 5′-phosphoryls and short cohesive termini of four nucleotides, pApApTpT. The most striking feature of the sequence is its symmetry. PMID:4343974

Äriühingute vastastikune tunnustamine ja asukohavahetus Euroopa Liidus / Andres Vutt

Index Scriptorium Estoniae

Vutt, Andres, 1969-

2007-01-01

Äriühingute vastastikuse tunnustamise põhimõtetest ja võimalustest, kuidas saab Euroopa Liidus muuta äriühingu asukohta ühest riigist teise ning mida tuleb Eestil seoses sellega arvestada. Äriühingute asukohavahetusest Euroopa Kohtu lahendites. Artikkel on valminud ETF-i grandi 6747 abil

Remedial Investigation/Feasibility Study (RI/FS) process, elements and techniques guidance

Energy Technology Data Exchange (ETDEWEB)

1993-12-01

This manual provides detailed guidance on Remedial Investigation/Feasibility Studies (RI/FSs) conducted pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) at Department of Energy (DOE) facilities. The purpose of the RI/FS, to assess the risk posed by a hazardous waste site and to determine the best way to reduce that risk, and its structure (site characterization, risk assessment, screening and detailed analysis of alternatives, etc.) is defined in the National Oil and Hazardous Substances Pollution Contingency Plan (NCP) and further explained in the Environmental Protection Agency`s (EPA`s) Guidance for Conducting Remedial Investigations and Feasibility Studies Under CERCLA (Interim Final) 540/G-89/004, OSWER Directive 9355.3-01, October 1988. Though issued in 1988, the EPA guidance remains an excellent source of information on the conduct and structure of an RI/FS. This document makes use of supplemental RI/FS-related guidance that EPA has developed since its initial document was issued in 1988, incorporates practical lessons learned in more than 12 years of experience in CERCLA hazardous site remediation, and drawing on those lessons, introduces the Streamlined Approach For Environmental Restoration (SAFER), developed by DOE as a way to proceed quickly and efficiently through the RI/FS process at DOE facilities. Thus as its title implies, this guidance is intended to describe in detail the process and component elements of an RI/FS, as well as techniques to manage the RI/FS effectively.

Interaction between two predator mites of Tetranychus urticae koch (Acariformes: Tetranychidae) in laboratory

International Nuclear Information System (INIS)

Arguelles R, Angelica; Plazas, Natali; Bustos R, Alexander; Cantor R, Fernando; Rodriguez, Daniel; Hilarion, Alejandra

2013-01-01

Tetranychus urticae (Acari: Tetranychidae) is an important pest of ornamental crops. A species of predatory mite used for its control is Neoseiulus californicus and Phytoseiulus persimilis (Acari: Phytoseiidae). This research proposes the use of joint releases of the two cited predators for the control of the pest. Several situations leading to interaction were evaluated: high density of one predator and low density of the other one, being the prey present or absent. The scenario with predators in equal densities and in presence of the prey was also evaluated. When a predator is in higher density and the prey present, the predator with the lower density increases the interference with the consumption of preys by the predator with higher density. On the other hand, when the consumption of T. urticae reduces, intraguild predation increases. P. persimilis shows intraguild predation behavior when t. urticae is absent and N. californicus is present, consuming all developmental stages of its conspecific. Instead, N. californicus only feed on conspecific larvae, when the fitofagous was absent and P. persimilis was present. When the two predators were present in the same assemblage and with the same population density, the quantity of T. urticae consumed by both of them was not higher than the consumed one when each predator was present in separate way.

Jüri Naela rahakotti prantsatas miljon krooni / Aigi Viira

Index Scriptorium Estoniae

Viira, Aigi

2009-01-01

Tallinna Ülikooli tantsukompositsiooni dotsent Jüri Nael sai Eesti haridus- ja teadusministeeriumilt miljonikroonise stipendiumi doktoriõpinguteks Londonis Royal Holloway University's. Jüri Nael pühendub Londonis õppides sellele, mis jääb teatri ja tantsu vahele ehk füüsilisele teatrile, täpsemalt – füüsilisele eksperimentaalteatrile

Statistical dynamic imaging of RI-labeled tracer from list-mode PET data

International Nuclear Information System (INIS)

Tanimoto, Michiaki; Kuroda, Yoshihiro; Oshiro, Osamu; Watabe, Hiroshi; Kuroda, Tomohiro

2009-01-01

Positron emission tomography (PET) can be used in physiological analysis to illustrate physiological states by visualizing the accumulation of radioisotope (RI)-labeled tracer in specific organs or tissues. PET obtains spatio-temporal statistics in the form of list-mode data. However, conventional imaging techniques, which sum up list-mode data over a given time period, cannot depict detailed temporal dynamics of the RI-labeled tracer. In this study, a spatio-temporal analysis approach was employed to visualize the temporal flow dynamics of RI-labeled tracer from the obtained list-mode data. Experiments to assess the visualization of simulated RI-labeled tracer dynamics as well as RI-labeled tracer dynamics in a vascular phantom showed that the proposed method successfully depicted detailed temporal flow dynamics that could not be visualized using conventional methods. (author)

Imaging of the bronchial blood flow using RI-angiography

International Nuclear Information System (INIS)

Fujii, Tadashige; Hirayama, Jiro; Kanai, Hisakata; Kobayashi, Toshio; Handa, Kenjiro

1979-01-01

RI-angiography with sup(99m)TcO 4 - was carried out using a scintillation camera with a digital minicomputer for the purpose of imaging of bronchial blood flow in various lung diseases, and as application of dual radioisotope techniques, other imagings such as tumor imaging with 197 HgCl 2 or 67 Ga-citrate and/or perfusion imaging with sup(99m)Tc-MAA, were performed simultaneously in patients remaining the same position, too. The image as a iso-count map extracted out of the image of 197 HgCl 2 , 67 Ga-citrate or sup(99m)Tc-MAA, was superimposed to the brightness image of RI-angiogram (aortic phase). By these procedures, the image of bronchial blood flow were obtained in some patients with lung cancer, pulmonary tuberculosis, lung abscess, and chronic bronchitis. The dual radioisotope techniques using RI-angiography and the other imaging were useful to make isotope diagnosis of lung diseases more reliable, and the image superimposition methods using RI-angiogram and the image of tumor of perfusion, were useful to improve anatomic orientation of the former. (author)

Analysis of concept and application or Risk-Informed Performed-Based Regulation (RI-PBR)

International Nuclear Information System (INIS)

Kim, W. S.; Sung, K. Y.; Lee, C. J.; Kim, H. J.

2002-01-01

For improving regulation of nuclear power plants, the USNRC is adopting the Risk-Informed Performance-Based Regulation (RI-PBR) as an alternative, in parallel with implementing current deterministic regulation. This paper introduces a research plan for 'Institutionalization of RI-PBR' that is being conducted by KINS as a national project for evaluating feasibility for application of the alternative to Korean regulation system. Analysis of regulation characteristics, case study and experience on RI-PBR were presented as interim research results. In addition, the future plan of development of RI-PBR concept as understandable to the public and evaluation of level of techniques needed for implementation of RI-PBR was introduced

Deficiência de tiamina como causa de cor pulmonale reversível

Directory of Open Access Journals (Sweden)

Liana S. Coelho

2008-07-01

Full Text Available A deficiência de tiamina pode apresentar quatro formas clássicas de apresentação clínica: polineuropatia periférica, anorexia e fraqueza muscular (beribéri seco; insuficiência cardíaca de alto débito com sinais congestivos (beribéri úmido; beribéri associado ao choque (Shoshin beribéri e encefalopatia de Wernicke. Neste relato, descrevemos quadro sugestivo de hipertensão pulmonar grave e cor pulmonale, com estase jugular, hepatite congestiva e edema generalizado, que apresentou reversão completa após administração de tiamina.

Üksikud naljakad peaaegu kolmikud / Jüri Viikberg ; tlk. Jüri Viikberg

Index Scriptorium Estoniae

Viikberg, Jüri 1953-

2005-01-01

Arvustus: Punttila, Matti. Haaskannäköinen tyttö : kielikaskuista sanaleikkeihin. Helsinki, 1998 ; Punttila, Matti. Pilkettä silmäkulmaan : kielikaskuista sanaleikkeihin. Helsinki, 2001 ; Punttila, Matti. Poskettomia huulia : kielikaskuista sanaleikkeihin. Helsinki, 2004. Näiteid: Kui keel ei püsi hammaste taga ; Sõna keeles ja keel hammaste vahel / tõlkinud Jüri Viikberg // Oma Keel, 1995, nr. 1, lk. 55-56, 63-64

Efeito da respiração diafragmática sobre a variabilidade da frequência cardíaca na doença cardíaca isquêmica com diabete

OpenAIRE

Kulur, Anupama Bangra; Haleagrahara, Nagaraja; Adhikary, Prabha; Jeganathan, P. S.

2009-01-01

FUNDAMENTO: A diminuição da variabilidade da frequência cardíaca (VFC) está associada com um prognóstico desfavorável em pacientes com doença cardíaca isquêmica (DCI) e diabete. Ainda não foi provado em definitivo se a mudança no padrão respiratório pode modificar o fator de risco nesses pacientes. OBJETIVO: Avaliar o efeito da respiração diafragmática sobre a VFC em pacientes diabéticos com DCI. MÉTODOS: A população do estudo consistiu em 145 pacientes do sexo masculino selecionados ao acaso...

RiTSE/KCGE: Application of artificial intelligence to improve plant availability

International Nuclear Information System (INIS)

Frank, M.V.; Epstein, S.A.

1986-01-01

Maintenance and other personnel related errors are a major cause of reactor trips in some U.S. plants. Software called RiTSE and KCGE, that can operate on a mini-computer work station, has been developed to dramatically reduce trips caused by clearance coordination problems. Such problems arise because of the enormous number of components that interrelate in ways that cannot always be anticipated during plant operation. Concurrent maintenance, test, surveillance and other operations activities contribute to the unanticipated interactions. RiTSE allows the appropriate plant personnel (i.e., those responsible for authorizing work during start-up and operation) to predict if their next authorizations would cause a reactor trip. With KCGE, RiTSE can warn these personnel of a condition of significantly reduced margin to trip. RiTSE also aids post-trip cause analysis by pointing out those components that could have contributed to the trip. It is believable that use of RiTSE is a quicker and more reliable way to authorize work during operation than reliance on memory and drawings. The software provides maximum benefit when used in conjunction with a configuration management program that assures accurate plant presentation and accurate updating of component status during operation. Application of RiTSE and KCGE to a client's PWR demonstrated part of their potential benefits. (Nogami, K.)

75 FR 57819 - Notice of Revision; Notice of the Advisory Committee on Apprenticeship (ACA) Open Meeting and New...

Science.gov (United States)

2010-09-22

... DEPARTMENT OF LABOR Employment and Training Administration Notice of Revision; Notice of the Advisory Committee on Apprenticeship (ACA) Open Meeting and New Members AGENCY: Employment and Training... that the Committee Charter has been recently renewed. The current 2009 ACA charter remains in effect...

Genealogy of gas cells for low-energy RI-beam production

Energy Technology Data Exchange (ETDEWEB)

Wada, Michiharu, E-mail: mw@riken.jp

2013-12-15

Highlights: • In order to overcome serious limitations in the universality of the traditional isotope separator on-line technique, various endeavors have been made on gas catcher cells for converting relativistic RI-beams from in-flight separators to low-energy RI-beams. • The origin of the gas catcher is found in the IGISOL (Ion guide isotope separator on-line) technique. • Many developments have been made over the years to overcome the various difficulties and drawbacks found in the IGISOL technique. -- Abstract: In order to overcome serious limitations in the universality of the traditional isotope separator on-line technique, various endeavors have been made on gas catcher cells for converting relativistic RI-beams from in-flight separators to low-energy RI-beams. The origin of the gas catcher is found in the IGISOL (Ion guide isotope separator on-line) technique. Many developments have been made over the years to overcome the various difficulties and drawbacks found in the IGISOL technique.

Genealogy of gas cells for low-energy RI-beam production

International Nuclear Information System (INIS)

Wada, Michiharu

2013-01-01

Highlights: • In order to overcome serious limitations in the universality of the traditional isotope separator on-line technique, various endeavors have been made on gas catcher cells for converting relativistic RI-beams from in-flight separators to low-energy RI-beams. • The origin of the gas catcher is found in the IGISOL (Ion guide isotope separator on-line) technique. • Many developments have been made over the years to overcome the various difficulties and drawbacks found in the IGISOL technique. -- Abstract: In order to overcome serious limitations in the universality of the traditional isotope separator on-line technique, various endeavors have been made on gas catcher cells for converting relativistic RI-beams from in-flight separators to low-energy RI-beams. The origin of the gas catcher is found in the IGISOL (Ion guide isotope separator on-line) technique. Many developments have been made over the years to overcome the various difficulties and drawbacks found in the IGISOL technique

Tallinna linnapea Jüri Ratas : Keskerakond ei ole maffia! / Jüri Ratas ; interv. Urmo Soonvald

Index Scriptorium Estoniae

Ratas, Jüri, 1978-

2005-01-01

Tallinna linnapea Jüri Ratas vastab küsimustele, mis puudutavad Rein Ratase Tallinna Vee nõukogu liikmeks määramist, K-kohukse reklaami seost Keskerakonna valimiskampaaniaga, linnapeaks saamist, koostööd teiste poliitikutega, Edgar Savisaare osa Tallinna linna juhtimises

The "ACA Code of Ethics": Articulating Counseling's Professional Covenant

Science.gov (United States)

Ponton, Richard F.; Duba, Jill D.

2009-01-01

The "ACA Code of Ethics" (American Counseling Association, 2005) is an articulation of the ever-changing relationship between counseling professionals and society. It provides clear parameters of behaviors to meet the changing needs of the people counselors are called to serve. This article reviews the 2005 "Code" as both a statement of counselor…

Insuficiência cardíaca: estratégias usadas por idosos na busca por qualidade de vida

Directory of Open Access Journals (Sweden)

Analyane Conceição Silva dos Santos

2011-10-01

Full Text Available Estudo descritivo com abordagem qualitativa cujos objetivos foram identificar as repercussões da insuficiência cardíaca na qualidade de vida dos idosos; descrever as estratégias utilizadas no enfrentamento destas repercussões e conhecer as percepções acerca dos cuidados de enfermagem. Foram realizadas entrevistas semiestruturadas com dez idosos com insuficiência cardíaca em um hospital militar do Rio de Janeiro-RJ. Identificou-se que a insuficiência cardíaca gera repercussões emocionais, físicas e financeiras na vida dos idosos, ocasionando impacto na qualidade de vida. Dentre as estratégias criadas pelos idosos, verificou-se o enfrentamento paliativo e o enfrentamento emocional. Os cuidados de enfermagem evidenciados foram orientação, carinho, zelo e dedicação. Cuidar do idoso com insuficiência cardíaca implica em avaliar as repercussões na capacidade funcional e autonomia dos anciãos, exigindo habilidades e competências do enfermeiro para identificar suas especificidades na perspectiva de um cuidado integral que contribua para a qualidade de vida dos mesmos.

Importancia de los aspectos psicosociales en la enfermedad celíaca

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Trini Fragoso Arbelo

2002-06-01

Full Text Available Se revisan los conceptos clínicos actuales sobre la enfermedad celíaca. Se definen con precisión los términos enfermedad celíaca activa, silente, latente y potencial. Se enfatiza en los aspectos psicosociales que influyen en su tratamiento y se trazan pautas generales acerca del manejo integral de los pacientes afectados, dada la importancia de la dieta sin gluten de por vida como único tratamiento.The current clinical concepts of celiac disease are reviewed. The terms active, silent, latent and potential related to celiac disease are accurately defined. Emphasis is made on the psychosocial aspects influencing its treatment and general guidelines are drawn on the comprehensive management of the patients suffering from this disease, given the importance of diet without gluten as the only lifelong treatment.

Yeast transformation mediated by Agrobacterium strains harboring an Ri plasmid: comparative study between GALLS of an Ri plasmid and virE of a Ti plasmid.

Science.gov (United States)

Kiyokawa, Kazuya; Yamamoto, Shinji; Sato, Yukari; Momota, Naoto; Tanaka, Katsuyuki; Moriguchi, Kazuki; Suzuki, Katsunori

2012-07-01

Agrobacterium strains containing a Ti plasmid can transfer T-DNA not only to plants but also to fungi, including the yeast Saccharomyces cerevisiae. However, no Agrobacterium strain harboring an Ri plasmid has been evaluated in fungal transformation. Some Ri plasmids have GALLS , instead of virE1 and virE2. GALLS protein can functionally substitute in plant transformation for a structurally different protein VirE2. In this study, we compared the yeast transformation ability among Agrobacterium donors: a strain containing a Ti plasmid, strains harboring either an agropine-type or a mikimopine-type Ri plasmid, and a strain having a modified Ri plasmid supplemented with a Ti plasmid type virE operon. Agrobacterium strains possessing GALLS transformed yeast cells far less efficiently than the strain containing virE operon. Production of GALLS in recipient yeast cells improved the yeast transformation mediated by an Agrobacterium strain lacking neither GALLS nor virE operon. A reporter assay to detect mobilization of the proteins fused with Cre recombinase revealed that VirE2 protein is much more abundant in yeast cells than GALLS. Based on these results, we concluded that the low yeast transformability mediated by Agrobacterium strains having the Ri plasmid is because of low amount of mobilized GALLS in yeast cells. © 2012 The Authors Journal compilation © 2012 by the Molecular Biology Society of Japan/Blackwell Publishing Ltd.

Influência do treino na variabilidade da frequência cardíaca em triatletas

OpenAIRE

Salvador, Bruno Carlos Nunes

2011-01-01

Mestrado em Treino de Alto Rendimento O objectivo deste estudo foi estudar a variabilidade da frequência cardíaca (VFC) em repouso durante um estágio de vinte e dois dias, a altitude moderada, e verificar como a carga de treino se relaciona com os parâmetros da variabilidade de frequência cardíaca. No estudo participaram 5 triatletas pertencentes à selecção de triatlo de Portugal (17,4± 1,8 anos), quatro do sexo masculino e uma do sexo feminino. Procedeu-se ao registo da activi...

Näitus "Sajand eesti puugravüüri klotsidel" / Jüri Hain

Index Scriptorium Estoniae

Hain, Jüri, 1941-

2007-01-01

Eesti Rahvusraamatukogus 15. I-3. II eksponeeritud ja rahvusraamatukogu kollektsioonist koostatud näitusest "Sajand eesti puugravüüri klotsidel: 1840-1940". Järgmistest kunstnikest ja nende töödest: Aleksander Otto Gern, Bogdan Gottlieb Friedrich Kally, August Daugell, Hermann Eduard Hartmann, Eduard Magnus Jakobson, Mart Pukits, Andres Kuusk, Karl Friedrich Schnell, Anton Suurkask (1873-1965), Arkadio Laigo, Hando Mugasto, Eduard Järv, Richard Kaljo, Ott Kangilaski, Ants Puks (1918-?), Salome Trei

Äri- ja ettevõtluskeeldude piiriülene mõju / Maarja Torga, Juhan Sarv

Index Scriptorium Estoniae

Torga, Maarja, 1984-

2017-01-01

Eestis kohaldatud äri- ja ettevõtluskeeldude piiriülesest mõjust ning välisriigis kohaldatud äri- ja ettevõtluskeelu mõjust Eestis. Äri- ja ettevõtluskeeldude piiriülesest tsiviilõiguslikust ja karistusõiguslikust mõjust. Sisaldab asjakohast kohtupraktikat

Senate Republican leadership releases revised ACA repeal and replace bill

Directory of Open Access Journals (Sweden)

Moore NS

2017-07-01

Full Text Available No abstract available. Article truncated after first 150 words. Today, the Senate Republican leadership released a revised version of a bill to repeal and replace the Affordable Care Act (ACA. The new bill draft includes an amendment sponsored by Sen. Cruz (R-TX that permits insurers to offer health insurance plans on the ACA exchanges that do not cover the ACA’s 10 essential health benefits (EHB as long as they offer at least one other plan that provides full coverage of EHB’s. The bill also includes more funding for opioid addiction and for state initiatives to reduce insurance premiums and additionally, some flexibility for state Medicaid funding in the event of a public health crisis. The bill must still receive a cost estimate from the Congressional Budget Office (CBO, which will include the impact of the bill on insurance coverage levels, expected out Monday. The ATS remains deeply concerned about the bill because under the Cruz proposal, insurance coverage costs …

Reiu Tüüri maratonloeng kunstiturust / Reiu Tüür

Index Scriptorium Estoniae

Tüür, Reiu

2001-01-01

27. VI toimus Pärnus Kunstplatze Unobomberi galeriis Reiu Tüüri näitus-loeng kaasaegse kunsti galeriidest Londonis ja Eestis. Näitus on osa R. Tüüri sel sügisel Londoni linnaülikooli juures kaitstavast kunsti mänedzhmendi alasest magistritööst "Eesti kaasaegse kunsti turg". Juhendaja Jani Robertson Hollandist.

Messy but Fair: The ACA's Hospital Value-Based Purchasing Program and the Notice-and-Comment Process.

Science.gov (United States)

Pan, Janus

2017-01-01

The Centers for Medicare and Medicaid Services (CMS) promulgated a new Medicare program called the Value-Based Purchasing Program (VBPP) as part of the 2010 Affordable Care Act (ACA). Like many other regulatory agencies, CMS used the Notice-and-Comment process to issue proposed rules, solicit public comments, and then publish final rules. Conventional literature suggests that CMS should disproportionately favor business interests during the Notice-and-Comment process, mainly due to the business interests' greater resources and capacity to draft well-reasoned comments. However, this article argues against this presumption and contends instead that CMS listens equally well to both business interest comments and private citizen comments during the formation of the VBPP. With regard to the VBPP and the ACA, CMS appears to be resisting disproportionate sway by business interests and is instead privileging the ACA's goal of improving healthcare quality.

Tratamento cirúrgico de um aneurisma primário de veia ilíaca externa

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Márcio Luís Lucas

2015-09-01

Full Text Available ResumoAneurismas primários da veia ilíaca são extremamente raros e podem complicar com trombose, embolia pulmonar ou ruptura. Acredita-se que existam apenas 14 casos descritos na literatura. Neste artigo, descrevemos um caso de um jovem de 25 anos, que apresentava edema e cianose do membro inferior esquerdo. A ecografia vascular revelou uma massa cística em fossa ilíaca esquerda. A angiotomografia confirmou o diagnóstico de um aneurisma da veia ilíaca externa esquerda de 3,8 cm, no maior diâmetro. O paciente foi submetido ao tratamento cirúrgico através da ressecção do aneurisma seguida de venorrafia longitudinal. Teve boa evolução pós-operatória, com um seguimento clínico de 44 meses. Houve uma melhora do edema no membro inferior esquerdo, sem complicações tardias.

77 FR 65395 - Air Cargo Advance Screening (ACAS) Pilot Program

Science.gov (United States)

2012-10-26

... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Air Cargo Advance Screening (ACAS) Pilot Program Correction In notice document 2012-26031 appearing on pages 65006-65009 in the issue of October 24, 2012 make the following correction: On page 65007, in the first column, under the...

Investigations on the Effects of Five Different Plant Extracts on the Two-Spotted Mite Tetranychus urticae Koch (Arachnida: Tetranychidae

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Pervin Erdogan

2012-01-01

Full Text Available Two-spotted mite, Tetranychus urticae Koch (Arac.: Tetranychidae, is an economic pest worldwide including Turkey, causing serious damage to vegetables, flowers, and fruit crops. In recent years, broad-spectrum insecticides/miticides have been used to control this pest in Turkey. Control is difficult mainly due to resistance to conventional pesticides. This study was conducted to determine efficacy of pesticides extracted from five different plants [i.e., Allium sativum L. (Amaryllidaceae, Rhododendron luteum S. (Ericaceae, Helichrysum arenarium L. (Asteraceae, Veratrum album L. (Liliaceae, and Tanacetum parthenium L. (Asteraceae] against this mite. Bioassays were tested by two different methods to determine the effects of varying concentrations. Experiments were performed using 3 cm diameter leaf disk from unsprayed bean plants (Phaseolus vulgaris L.. In addition, the effects of the extracts on reproduction and oviposition were investigated. The extract yielded high mortality. In the lowest-concentration bioassays, the adult mites laid lower numbers of eggs compared to the untreated control. No ovicidal effect was observed.

Competency remodelling and application plans for development of job competency in RI-biomics

Energy Technology Data Exchange (ETDEWEB)

Shin, Woo Ho; Park, Tai Jin [Korean Association for Radiation Application, Seoul (Korea, Republic of)

2017-03-15

RI-Biomics technology is advanced convergence technologies that can be measured in real time and track in vivo behavior and metabolism of substances using characteristics of the radioactive isotope. Its application fields are increasing such as drug development, agriculture, development of new materials and their utilization, etc. In addition, according to domestic and international developments and changes in the RI-Biomics environment, RI-Biomics professionals are needed to train continuously. To develop systematic human resources basement and competency-based curriculum, we perform competency modeling of pedagogical perspective to targeted at high-performance on RI-Biomics. Furthermore, we redefine the competency model and verified by industry experts with focus group interviews. In the result, two general competencies and three professional competencies were extracted by interview. Each competencies are organized six sub-competencies and nine sub-competencies. In the final steps, the same procedures were repeated to obtain the consensus of experts on derived competencies and behavioral objectives. The results of the study are applicable to enhance human resource management and to develop the curriculum for RI-Biomics expert training. It is expected to be used as reference material of long term-planning for RI-Biomics professional.

Competency remodelling and application plans for development of job competency in RI-biomics

International Nuclear Information System (INIS)

Shin, Woo Ho; Park, Tai Jin

2017-01-01

RI-Biomics technology is advanced convergence technologies that can be measured in real time and track in vivo behavior and metabolism of substances using characteristics of the radioactive isotope. Its application fields are increasing such as drug development, agriculture, development of new materials and their utilization, etc. In addition, according to domestic and international developments and changes in the RI-Biomics environment, RI-Biomics professionals are needed to train continuously. To develop systematic human resources basement and competency-based curriculum, we perform competency modeling of pedagogical perspective to targeted at high-performance on RI-Biomics. Furthermore, we redefine the competency model and verified by industry experts with focus group interviews. In the result, two general competencies and three professional competencies were extracted by interview. Each competencies are organized six sub-competencies and nine sub-competencies. In the final steps, the same procedures were repeated to obtain the consensus of experts on derived competencies and behavioral objectives. The results of the study are applicable to enhance human resource management and to develop the curriculum for RI-Biomics expert training. It is expected to be used as reference material of long term-planning for RI-Biomics professional

Teel kriisist õigusriiki / Jüri Raidla

Index Scriptorium Estoniae

Raidla, Jüri, 1957-

1990-01-01

Jüri Raidla, justiitsminister (kinnitati 17. 04. 1990). Sündinud 1957. a. Pärnus, 1980. a. lõpetas Tartu Ülikooli õigusteaduskonna, kaitses 12. 02. 1987. a. Leningradi Ülikoolis väitekirja "Mehaaniliste transpordivahenditega kahju tekitamisest tulenevad kohustused"

Pealinlased olid aktiivsemad valijad / Jüri Ratas

Index Scriptorium Estoniae

Ratas, Jüri, 1978-

2007-01-01

Ilmunud ka: Stolitsa, 14. märts 2007, lk. 2. Tallinna linnapea Jüri Ratas parlamendivalimiste tulemustest. Vt. samas: Kes Tallinnast riigikokku valiti?; Riigikogu valimise tulemused Tallinnas: diagramm

Pengaruh Minyak Atsiri Asal Kulit Jeruk Manis dan Besar terhadap Perkembangan Tungau Panonychus citri (Acarina: Tetranychidae

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Mizu lstianto

2003-12-01

Full Text Available P. citri (Acarina: Tetranychidae is one of the economically important citrus pests in Indonesia. However, the association of this pest with its host is not well understood. The objective of this research was to evaluate the effects of essential oil extracted from sweet orange and pumello fruit peels on the development of P. citri. The research was conducted in the laboratory of IP2TP Tlekung Malang, using a complete random design consisted of six treatments. Fifteen mites were used for each treatment. The treatments were concentrations 10, 20, 40, and 80 ppm of essential oil. Parafin was used as a positive control because it was a diluting solution for the essential oil. The control received no application. The result showed that the main content of essential oil extracted from sweet orange and pumello was limonene. The essential oils prolonged the life cycle and reduced the fecundity of P. citri. The effects of essential oil extracted from pumello were found to be more pronounced than were from sweet orange. These differences might be due to the differences in the composition of the volatile compounds other than limonene.

Euroopa äriühingu mudel ja selle rakendamine finantssektori äriühingute poolt / Ingrid Ulst

Index Scriptorium Estoniae

Ulst, Ingrid, 1977-

2005-01-01

SE (Euroopa äriühingu) mudeli olemusest ja SE regulatsiooni olulisematest aspektidest, põgusalt Nordea Bank AB praegusest grupistruktuurist ja võimalikust restruktureerimisest. Lisatud tabel: Nordea Bank AB olulisemad grupiettevõtted ja järelevalve (01/01/2004)

Registro Nacional de Internación por Insuficiencia Cardíaca

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Raúl Borracci

2009-01-01

Full Text Available IntroducciónLa insuficiencia cardíaca representa una de las principales causas de internación con una tasa elevada de complicaciones y cuyo enfoque no parece que haya mejorado en los últimos años.ObjetivosConocer el perfil epidemiológico y clínico, analizar las medidas terapéuticas y la evolución durante la internación y a los 3 meses de pacientes admitidos por insuficiencia cardíaca descompensada.Material y métodosRegistro prospectivo, multicéntrico de pacientes internados por insuficiencia cardíaca descompensada en 31 centros de todo el país que aceptaron la invitación a participar del registro. Se analizaron variables vinculadas con la presentación y la evolución hospitalaria y a los 90 días.ResultadosSe incluyeron 736 pacientes, mediana de edad 74 años (64-82, 41% mujeres, 75% hipertensos, 27% diabéticos, 20% infarto previo, 30% fibrilación auricular crónica, 17% insuficiencia renal crónica, 18% EPOC. Sólo el 29% era de etiología isquémico-necrótica. El 47% había tenido internación en el último año por insuficiencia cardíaca. Las causas de descompensación más frecuentes fueron infecciones, suspensión del tratamiento y transgresión alimentaria.Las formas graves de presentación (shock cardiogénico, edema agudo de pulmón, anasarca representaron el 30%. El 60% de los pacientes se internaron en área crítica. La mediana de permanencia fue de 7 (5-11 días. La mortalidad hospitalaria fue del 8%. A los 90 días, la reinternación fue del 24,5% y la mortalidad posalta fue del 12,8%.ConclusionesEl presente registro confirma que se trata de una población de edad avanzada con una incidencia alta de comorbilidades. Muchas descompensaciones ocurren por factores prevenibles. La tasa de complicaciones es elevada y no se redujo en la última década.REV ARGENT CARDIOL 2009;77:33-39.

A soluble form of the high affinity IgE receptor, Fc-epsilon-RI, circulates in human serum.

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Eleonora Dehlink

Full Text Available Soluble IgE receptors are potential in vivo modulators of IgE-mediated immune responses and are thus important for our basic understanding of allergic responses. We here characterize a novel soluble version of the IgE-binding alpha-chain of Fc-epsilon-RI (sFcεRI, the high affinity receptor for IgE. sFcεRI immunoprecipitates as a protein of ∼40 kDa and contains an intact IgE-binding site. In human serum, sFcεRI is found as a soluble free IgE receptor as well as a complex with IgE. Using a newly established ELISA, we show that serum sFcεRI levels correlate with serum IgE in patients with elevated IgE. We also show that serum of individuals with normal IgE levels can be found to contain high levels of sFcεRI. After IgE-antigen-mediated crosslinking of surface FcεRI, we detect sFcεRI in the exosome-depleted, soluble fraction of cell culture supernatants. We further show that sFcεRI can block binding of IgE to FcεRI expressed at the cell surface. In summary, we here describe the alpha-chain of FcεRI as a circulating soluble IgE receptor isoform in human serum.

[Mihai Eminescu luulefestivalil osales Jüri Talvet

Index Scriptorium Estoniae

2014-01-01

Mihai Eminescu luulefestivalil esitleti mahukat tõlkeantoloogiat "Antologia poeziei universal de astăzi" (Craiova: Editura Europa”, 2014), mille on koostanud Ion Deaconescu. Antoloogias on ka Jüri Talveti luulet

Laser spectroscopy of exotic RI atoms in superfluid helium-OROCHI experiment

International Nuclear Information System (INIS)

Furukawa, T.; Matsuo, Y.; Hatakeyama, A.; Fujikake, K.; Matsuura, Y.; Kobayashi, T.; Shimoda, T.

2010-01-01

We have been developing a new laser spectroscopic technique 'OROCHI,' which is based on the combination of superfluid helium as a stopper of radioactive isotope (RI) beam and in-situ laser spectroscopy of RI atoms, for determining spins and moments of exotic RIs. By using this unique technique, it is feasible to measure nuclear spins and electromagnetic moments of extremely low yield RI (estimated as less than 1 pps). Recently, we have demonstrated that nuclear spins and moments are obtained from Zeeman and hyperfine splittings of stable Rb isotopes measured using this OROCHI technique. Details of this laser spectroscopy method in He II 'OROCHI' and the summary of our development are presented.

Taquiarritmias postoperatorias en la cirugía cardíaca del adulto. Profilaxis

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Fernando Enríquez

2010-10-01

Full Text Available Las arritmias en el periodo postoperatorio de la cirugía cardíaca suelen ser un hallazgo común ligado a múltiples mecanismos. Las condiciones particulares inherentes al acto quirúrgico pueden iniciar, facilitar o agravar un evento arrítmico por modificaciones en el sustrato anatómico y en sus moduladores. Aunque tradicionalmente consideradas como arritmias transitorias, diversos estudios muestran su asociación con una mayor morbimortalidad, riesgo de ictus, compromiso hemodinámico, iatrogenia, estancia hospitalaria y mayor gasto sanitario. La presente revisión aborda la información de que disponemos de las taquiarritmias en el postoperatorio de la cirugía cardíaca, y las pautas de actuación basadas en la evidencia.

Bacteria and viruses modulate FcεRI-dependent mast cell activity 

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Aleksandra Słodka

2013-03-01

Full Text Available Undoubtedly, mast cells play a central role in allergic processes. Specific allergen cross-linking of IgE bound to the high affinity receptors (FcεRI on the mast cell surface leads to the release of preformed mediators and newly synthesized mediators, i.e. metabolites of arachidonic acid and cytokines. More and more data indicate that bacteria and viruses can influence FcεRI-dependent mast cell activation. Some bacterial and viral components can reduce the surface expression of FcεRI. There are also findings that ligation of Toll-like receptors (TLRs by bacterial or viral antigens can affect IgE-dependent mast cell degranulation and preformed mediator release as well as eicosanoid production. The synergistic interaction of TLR ligands and allergen can also modify cytokine synthesis by mast cells stimulated via FcεRI. Moreover, data suggest that specific IgE for bacterial or viral antigens can influence mast cell activity. What is more, some bacterial and viral components or some endogenous proteins produced during viral infection can act as superantigens by interacting with the VH3 domain of IgE. All these observations indicate that bacterial and viral infections modify the course of allergic diseases by affecting FcεRI-dependent mast cell activation. 

Descrição da artéria celíaca em pombos domésticos (Columba livia

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Marcelo Ismar Santana

2012-03-01

Full Text Available http://dx.doi.org/10.5007/2175-7925.2012v25n2p125 O presente estudo objetivou definir a origem e a distribuição da artéria celíaca e de seus ramos colaterais em 15 aves da espécie Columba livia, cedidas pelo Centro de Controle de Zoonoses de Brasília. Com a finalidade de marcar o sistema arterial dos espécimes, o tronco braquiocefálico esquerdo foi canulado e injetado com solução aquosa de látex corado. Posteriormente, procedeu-se a fixação das aves com solução aquosa de formol 10% e a dissecação com instrumentos adequados, obtendo-se os resultados a seguir. A artéria celíaca originou-se da face ventral da aorta descendente. O primeiro ramo colateral surgiu da própria artéria celíaca, constituindo a artéria esofágica. Posteriormente, artéria celíaca se bifurcou em dois ramos, denominados ramo esquerdo da artéria celíaca e ramo direito da artéria celíaca. O ramo esquerdo emitiu a artéria proventricular ventral, seguida das artérias esplênicas, da artéria proventricular dorsal e da artéria hepática esquerda. Por fim, o ramo esquerdo se bifurcou, originando as artérias gástricas ventral e esquerda. O ramo direito emitiu a artéria hepática direita, seguida da artéria ileal e da artéria gástrica direita. Por fim, o ramo direito prosseguiu como artéria pancreaticoduodenal. Os achados deste trabalho apresentaram grande similaridade com as linhagens de aves da espécie Gallus gallus, exceto pela ausência da artéria ileocecal, de ramos císticos e da artéria gástrica dorsal.

Võrguäri Eestis kiratseb / Indrek Kald

Index Scriptorium Estoniae

Kald, Indrek, 1974-

2004-01-01

Autor otsib põhjusi, miks tänavuse Interneti-kaupluste edetabeli koostamiseks saatis oma äritulemused vaid viis võrgukauplust. Zebra Infosüsteemide tegevjuhi Peeter Tamme arvamus e-äri kiratsemise põhjuste kohta

Disfunção da articulação sacro-ilíaca em jovens com dor lombar

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Carolina Ramírez Ramírez

Full Text Available INTRODUÇÃO: A dor lombar representa um problema de saúde pública. Estima-se que uma elevada porcentagem de casos de dor lombar (85-90% não tem uma causa conhecida. Acredita-se que a disfunção da articulação sacro-ilíaca possa explicar, em parte, essa alta porcentagem. OBJETIVO: Determinar a frequência da disfunção da articulação sacro-ilíaca em jovens com dor lombar e descrever possíveis associações com características sócio-demográficas, clínicas e antropométricas da população estudada. METODOLOGIA: A amostra foi selecionada por meio de entrevista direta. Sessenta e sete sujeitos (92,5% mulheres com idade média de 21 ± 2,1 participaram do estudo. Foi realizado exame físico que incluiu a avaliação da dor à palpação, amplitude de movimento da flexão do quadril, funcionalidade avaliada por meio do Oswestry Disability Index, e realização de quatro provas de provocação de dor da articulação sacro-ilíaca (Gaenslen, thigh thrust, compressão ilíaca e compressão sacra. O diagnóstico para disfunção da articulação sacro-ilíaca foi considerado positivo se pelo menos três das provas foram positivas. RESULTADOS: A frequência de disfunção da articulação sacro-ilíaca foi de 35,8% IC 95% (24,0-47,6. Foi observada associação da disfunção da articulação com diminuição de flexibilidade dos isquiotibiais, pontuação do Oswestry Disability Index e dor à palpação. Não foram encontradas associações estatisticamente significativas com as variáveis sócio-demográficas. CONCLUSÃO: A alta frequência de disfunção da articulação sacro-ilíaca encontrada sugere a possibilidade de detectar e intervir precocemente uma possível causa de dor lombar, evitando alterações funcionais de maior severidade.

Ein empirischer Validitätsvergleich der ACA, des ASE und des PCPM

DEFF Research Database (Denmark)

Meissner, Martin; Decker, Reinhold; Adam, Nadine

2011-01-01

The increasing complexity of many products makes high demands on methods used for measuring consumer preferences. In such cases, practitioners frequently use Adaptive Conjoint Analysis (ACA). However, compositional approaches also proved to be efficient. Recently, Srinivasan and Netzer (2011...

Study on the Contribution of Nuclear and RI Technology to the National Economy

International Nuclear Information System (INIS)

Lee, Man Ki; Moon, K. H.; Kim, S. S.

2004-12-01

This study evaluated the economic value addition of nuclear power generation technology and radio-isotope(RI) technology quantitatively by using modified Input-Output table. For the nuclear power generation technology, the economic effect of both power plant construction and operation was evaluated. On the other hand, the economic effect of the RI utilization on the national economy was evaluated for RI technology. Firstly, the total economic value addition from nuclear power generation(both construction and operation) was estimated as 1.4% of Gross Domestic Product(GDP) in 2000. Among them, 1.2% was from nuclear power plant operation and the rest was from construction. On the other hand, the economic value addition from RI technology has continuously increased. Its share of GDP increased from 0.30% in 1980 to 0.58 in 2000

77 FR 43514 - Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI

Science.gov (United States)

2012-07-25

...-AA01 Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI AGENCY: Coast Guard, DHS... Narragansett Bay, Rhode Island, and adding an offshore anchorage in Rhode Island Sound south of Brenton Point... rulemaking (NPRM) entitled ``Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI,'' in the...

Elagu eesti energia : Jaan ja Jüri Ojaver, Paul Rodgers / Reet Varblane

Index Scriptorium Estoniae

Varblane, Reet, 1952-

2001-01-01

Paul Rodgersi, Jüri ja Jaan Ojaveri ühisnäitusest "Koostöö" Rakvere Kesklinna galeriis. P. Rodgersilt ja Jüri Ojaverilt on väljas Viinist "Eesti energia" näituselt naasnud tööd, Jaan Ojaverilt minimalistlikud tööriistad-objektid

76 FR 18812 - Submission for Review: RI 30-10, Disabled Dependent Questionnaire

Science.gov (United States)

2011-04-05

... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: RI 30-10, Disabled Dependent Questionnaire... Dependent Questionnaire. As required by the Paperwork Reduction Act of 1995 (Pub. L. 104-13, 44 U.S.C... (202) 606-0910. SUPPLEMENTARY INFORMATION: The RI 30-10, Disabled Dependent Questionnaire, is used to...

76 FR 36582 - Submission for Review: Disabled Dependent Questionnaire, RI 30-10

Science.gov (United States)

2011-06-22

... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: Disabled Dependent Questionnaire, RI 30-10... Dependent Questionnaire. As required by the Paperwork Reduction Act of 1995 (Pub. L. 104-13, 44 U.S.C.... SUPPLEMENTARY INFORMATION: RI 30-10, Disabled Dependent Questionnaire, is used to collect sufficient information...

Helilooja Jüri Dmitrievi loominguline õhtu / Vladislav Horuzhenko

Index Scriptorium Estoniae

Horuzhenko, Vladislav

2006-01-01

Viiuldajast, pianistist ja heliloojast Jüri Dmitrievist. Loomingulisest õhtust 8. okt. Pärnu raekojas Pärnumaa Rahvakultuuri Keskseltsi korraldatava projekti "Inimesed Pärnumaa kultuurimaastikul" raames

A research on the empowerment plan for specialist in RI-biomics field

Energy Technology Data Exchange (ETDEWEB)

Shin, Wo Ho; Park, Tai Jin; Yeom, Yu Sun [Korea Association for Radiation Application, Seoul (Korea, Republic of); Park, Sang Hyun [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup (Korea, Republic of)

2014-12-15

Increasing utilization of radiation and RI (Radioisotope) in nuclear industry including non-power area has achieved sustainable development of radiation industry. Industries are no longer confined by a single technology or abilities but expanded for application gradually. RIBiomics fields are one of the convergence technology that is recognized on a high-tech industry. Unlike the conventional industry, RI-Biomics field needs to various specialists to perform related task. There is no domestic training program to educate the whole process. This study aims to suggest the plan for improvement of practical skills for specialists in RI-Biomics through development of our training program. For this purpose, we have first investigated the opinion about classification scheme from experts and then analyzed the results in order to reflecting our training program. Based on analyzed results, conformity assessment was executed to organize curriculum through status of constructed device and instructor in domestic. Our training program was performed jointly with KAERI (Korea Atomic Energy Research Institute). RI-Biomics center is prepared with facilities of overall experiment to improve quality of education. Due to the fact that specialists have routine task, we organized a five-day short course to reflect temporal difficulties. We performed a trial operation to 6 participants in RI-Biomics field. Through the survey for the specialists who participated in the program, we evaluated the efficiency of our training program. The results showed that participants were satisfied with the organized curriculum and educational materials. Therefore, our program is expected to be utilized as basic research data to develop feasible program for policy development and to improve practical skills in RI-Biomics.

A research on the empowerment plan for specialist in RI-biomics field

International Nuclear Information System (INIS)

Shin, Wo Ho; Park, Tai Jin; Yeom, Yu Sun; Park, Sang Hyun

2014-01-01

Increasing utilization of radiation and RI (Radioisotope) in nuclear industry including non-power area has achieved sustainable development of radiation industry. Industries are no longer confined by a single technology or abilities but expanded for application gradually. RIBiomics fields are one of the convergence technology that is recognized on a high-tech industry. Unlike the conventional industry, RI-Biomics field needs to various specialists to perform related task. There is no domestic training program to educate the whole process. This study aims to suggest the plan for improvement of practical skills for specialists in RI-Biomics through development of our training program. For this purpose, we have first investigated the opinion about classification scheme from experts and then analyzed the results in order to reflecting our training program. Based on analyzed results, conformity assessment was executed to organize curriculum through status of constructed device and instructor in domestic. Our training program was performed jointly with KAERI (Korea Atomic Energy Research Institute). RI-Biomics center is prepared with facilities of overall experiment to improve quality of education. Due to the fact that specialists have routine task, we organized a five-day short course to reflect temporal difficulties. We performed a trial operation to 6 participants in RI-Biomics field. Through the survey for the specialists who participated in the program, we evaluated the efficiency of our training program. The results showed that participants were satisfied with the organized curriculum and educational materials. Therefore, our program is expected to be utilized as basic research data to develop feasible program for policy development and to improve practical skills in RI-Biomics

Jüri Talvet maailmaluule tõlgendajana / Jüri Talvet’s Interpretations of World Poetry

OpenAIRE

Lauri Pilter

2016-01-01

Teesid: Tartu Ülikooli maailmakirjanduse professori, luuletaja, kirjandusteadlase ja hispaaniakeelse kirjanduse spetsialisti Jüri Talveti tõlketegevuse viljade hulka kuulub luulet ja proosat nii sajandeid vanast Hispaania klassikast kui ka 20. sajandil või tänapäeval romaani keeltes või inglise keeles loodud teostest. Käesolev artikkel keskendub sellele, kuidas professor Talvet on tõlgendanud luule ja poeetika, kuid ka kirjandusajaloo, iseäranis barokk-kirjanduse alaseid küsimusi oma kirjandu...

MicroRNAs: um novo paradigma no tratamento e diagnóstico da insuficiência cardíaca?

Directory of Open Access Journals (Sweden)

Vagner Oliveira-Carvalho

2012-04-01

Full Text Available MicroRNAs (miRNAs são um grupo recém-descoberto de pequenos RNAs, não codificantes, que representam uma das áreas mais estimulantes da ciência médica moderna por modularem uma enorme e complexa rede regulatória da expressão dos genes.Recentemente, linhas de evidências sugerem que os miRNAs desempenham um papel crucial na patogênese da insuficiência cardíaca. Alguns miRNAs altamente expressos no coração como o miR-1, miR-133 e miR-208 estão fortemente associados ao desenvolvimento da hipertrofia cardíaca, enquanto o exato papel de miR-21 no sistema cardiovascular permanece controverso. Os níveis séricos de miRNAs circulantes como o miR-423-5p estão sendo avaliados como potenciais biomarcadores no diagnóstico e prognóstico da insuficiência cardíaca.Por outro lado, a manipulação dos níveis de miRNAs usando técnicas como os mimetizadores de miRNAs (miRmimics e miRNAs antagônicos(antagomiRs está tornando cada vez mais evidente o enorme potencial dos miRNAs como promissoras estratégias terapêutica sna insuficiência cardíaca.

ACA: Phoenix of-or Cooked in-This Dumpster Fire of an Election.

Science.gov (United States)

Kirkner, Richard Mark

2016-10-01

Hillary Clinton and Donald Trump promise divergent approaches to the ACA if elected. Basically, Clinton wants to improve it; Trump promises to dismantle it. Of course, no president acts in a vacuum, and a lot will also depend on which party controls Congress.

The mosaic genome structure of the Wolbachia wRi strain infecting Drosophila simulans

DEFF Research Database (Denmark)

Klasson, Lisa; Westberg, Joakim; Sapountzis, Panagiotis

2009-01-01

genome of W. pipientis strain wRi that induces very strong cytoplasmic incompatibility in its natural host Drosophila simulans. A comparison with the previously sequenced genome of W. pipientis strain wMel from Drosophila melanogaster identified 35 breakpoints associated with mobile elements and repeated...... sequences that are stable in Drosophila lines transinfected with wRi. Additionally, 450 genes with orthologs in wRi and wMel were sequenced from the W. pipientis strain wUni, responsible for the induction of parthenogenesis in the parasitoid wasp Muscidifurax uniraptor. The comparison of these A...

Eksjuhtide hoogne kinnisvaraäri / Koit Brinkmann

Index Scriptorium Estoniae

Brinkmann, Koit

2007-01-01

Endised Skanska EMV juhid Jaanus Otsa ja Olaf Herman ajasid põhitöökoha kõrvalt tulusat eraäri. Lisad: Skanska partnerlus Mati Tusoviga; Palju firmasid, kuid samad nimed; Väljavõte Skanska eetikakoodeksist. Kommenteerib Mika Toivola

Reproductive parameters of Phytoseiulus macropilis (Banks fed with Tetranychus urticae Koch (Acari: Phytoseiidae, Tetranychidae in laboratory

Directory of Open Access Journals (Sweden)

G. C. Souza-Pimentel

Full Text Available Abstract Predatory mites that belong to the Phytoseiidae family are one of the main natural enemies of phytophagous mites, thus allowing for their use as a biological control. Phytoseiulus macropilis (Banks, 1904 (Acari: Phytoseiidae is among the main species of predatory mites used for this purpose. Tetranychus urticae Koch, 1836 (Acari: Tetranychidae is considered to be one of the most important species of mite pests and has been described as attacking over 1,100 species of plants in 140 families with economic value. The objective of the present study was to investigate, in the laboratory, the reproductive parameters of the predatory mite P. macropilis when fed T. urticae. Experiments were conducted under laboratory conditions at 25 ± 2 °C of temperature, 70 ± 10% RH and 14 hours of photophase. In addition, biological aspects were evaluated and a fertility life table was established. The results of these experiments demonstrated that the longevity of adult female was 27.5 days and adult male was 29.0 days. The population was estimated to increase approximately 27 times (Ro in mean generation time (T, which was 17.7 days. Lastly, the mite population grew 1.2 times/day (λ and doubled every 3.7 days (TD.

Evaluation of leachate quality from pentachlorophenol, creosote and ACA [ammoniacal chromium arsenate] preserved wood products

International Nuclear Information System (INIS)

Whiticar, D.M.; Letourneau, L.; Konasewich, D.

1994-01-01

A field study was conducted to evaluate the leachability characteristics of pentachlorophenol (PCP), creosote, and ammoniacal chromium arsenate (ACA) wood preservatives from freshly treated wood products. Test products included PCP-treated utility poles, creosote-treated timbers and marine pilings, and ACA-treated utility poles. Bundles of test products were placed over collection trays to collect the leachate generated by natural rainfall and by sprinkling with tap water. The sampling schedule was based on accumulated rainfall with samples taken at about every 15 mm from 15 mm to 150 mm. Analyses included pH, oil and grease, total organic carbon, ammonia, metals, polynuclear aromatic hydrocarbons (PAH), chlorinated and nonchlorinated phenols, resin acids, and fish toxicity. The study indicated that leachates from wood products freshly treated with ACA, creosote, and PCP have potential for aquatic toxicity if released to the environment. A decreasing trend was noted in both the arsenic and copper releases as cumulative precipitation increased. PCP releases remained constant over the course of the study while PAH releases showed no significant trend. Phenanthrene was found to be the main component in the releases. 28 refs., 18 figs., 7 tabs

Hispaania kirjanduse elav keha / Jüri Talvet

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

1996-01-01

Keha ja kehatus hispaania kirjanduses (Cervantese Dulcinea, Sancho Panza, don Quijote) ja maailmakirjanduses esinevate tegelaskujude näiteil : Ka Tõnu Õnnepalu Joonatanist romaanis 'Hind'. Ilmunud ka kogumikus: Talvet, Jüri. Tõrjumatu äär. Tartu : Ilmamaa, 2005, lk. 469-473

Preliminary Beam Irradiation Test for RI Production Targets at KOMAC

Energy Technology Data Exchange (ETDEWEB)

Yoon, Sang Pil; Kwon, Hyeok Jung; Kim, Han Sung; Cho, Yong Sub; Seol, Kyung Tae; Song, Young Gi; Kim, Dae Il; Jung, Myung Hwan; Kim, Kye Ryung; Min, Yi Sub [KAERI, Daejeon (Korea, Republic of)

2016-05-15

The new beamline and target irradiation facility has been constructed for the production of therapeutic radio-isotope. Sr-82 and Cu-67 were selected as the target isotope in this facility, they are promising isotope for the PET imaging and cancer therapy. For the facility commissioning, the irradiation test for the prototype-target was conducted to confirm the feasibility of radio-isotope production, the proto-type targets are made of RbCl pellet and the natural Zn metal for Sr-82 and Cu-67 production respectively, In this paper, an introduction to the RI production targetry system and the results of the preliminary beam irradiation test are discussed. the low-flux beam irradiation tests for proto-type RI target have been conducted. As a result of the beam irradiation tests, we could obtain the evidence of Sr-82 and Cu-67 production, have confirmed the feasibility of Sr-82 and Cu-67 production at KOMAC RI production facility.

Preliminary Beam Irradiation Test for RI Production Targets at KOMAC

International Nuclear Information System (INIS)

Yoon, Sang Pil; Kwon, Hyeok Jung; Kim, Han Sung; Cho, Yong Sub; Seol, Kyung Tae; Song, Young Gi; Kim, Dae Il; Jung, Myung Hwan; Kim, Kye Ryung; Min, Yi Sub

2016-01-01

The new beamline and target irradiation facility has been constructed for the production of therapeutic radio-isotope. Sr-82 and Cu-67 were selected as the target isotope in this facility, they are promising isotope for the PET imaging and cancer therapy. For the facility commissioning, the irradiation test for the prototype-target was conducted to confirm the feasibility of radio-isotope production, the proto-type targets are made of RbCl pellet and the natural Zn metal for Sr-82 and Cu-67 production respectively, In this paper, an introduction to the RI production targetry system and the results of the preliminary beam irradiation test are discussed. the low-flux beam irradiation tests for proto-type RI target have been conducted. As a result of the beam irradiation tests, we could obtain the evidence of Sr-82 and Cu-67 production, have confirmed the feasibility of Sr-82 and Cu-67 production at KOMAC RI production facility

Linnapea, keda rõõmustab titekisa / Jüri Ratas ; interv. Riina Luik

Index Scriptorium Estoniae

Ratas, Jüri, 1978-

2006-01-01

Tallinna linnapea vastab küsimustele, mis puudutavad tema suhtumist opositsiooni kriitikasse, linna juhtimist, perekonda, lapsepõlve, spordiga tegelemist, sõpruskonda, eraettevõtlusest loobumist ning suhteid kirikuga. Lisa: Jüri Ratas (27). Vt. samas lühiintervjuud linnapea abikaasa Karin Ratasega. Kommenteerib Jüri Ratase endine klassijuhataja Nõmme gümnaasiumist, võrkpallitreener Raimund Pundi

Evaluation of inventory change report (ICR) in 2008/2009 - 2012/2013 in MBA.RI-B

International Nuclear Information System (INIS)

Agustinus Suprijanto; Suratno; Sigit Pramana

2013-01-01

Evaluation has been performed for Inventory Change Report (ICR) in 2008/2009 - 2012/2013 in MBA.RI-B (MBA = Material Balance Area) (RI-B = Center for Accelerator and Material Process Technology). The evaluation performed on the inventory change report of nuclear material document. Changes in inventories occur when there is acceptance or shipment of nuclear materials outside nuclear facilities. Successive reports changes in inventory of nuclear material in 2008/2009 comprised 3 sheets ICR document numbers (153, 154 and 155), in 2009/2010 comprised 1 sheet ICR document number (159), in 2010/2011 comprised 3 sheets ICR document numbers (164, 165 and 166), and in 2012/2013 comprised 2 sheets ICR document numbers (175 and 176). From these data report changes in inventory of nuclear material can be concluded that in MBA.RI-B has been the displacement of nuclear material activities includes receipt of nuclear material from other nuclear facilities and shipments of nuclear materials out of facilities for research and development includes receipt 4 times from RI-E and 1 times from RI-A and 3 times shipment to RI-E. (author)

77 FR 5581 - Submission for Review: Financial Resources Questionnaire (RI 34-1, RI 34-17) and Notice of Amount...

Science.gov (United States)

2012-02-03

... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: Financial Resources Questionnaire (RI 34- 1... opportunity to comment on a revised information collection request (ICR) 3206-0167, Financial Resources... collection techniques or other forms of information technology, e.g., permitting electronic submissions of...

Arved Viirlaid teises kaanonis / Jüri Talvet

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

2002-01-01

Arved Viirlaid 80. Ka tema juubeliks ilmunud ingliskeelsest luulekogust "Selected poems" (tlk. Taimi Ene Moks ja R. W. Stedingh). Ilmunud ka kogumikus: Talvet, Jüri. Tõrjumatu äär. Tartu : Ilmamaa, 2005, lk. 417-420, pealk.: Teises Kaanonis: Viirlaiu luule inglise keeles

Endogenous IL-1 in cognitive function and anxiety: a study in IL-1RI-/- mice.

Directory of Open Access Journals (Sweden)

Carol L Murray

Full Text Available Interleukin-1 (IL-1 is a key pro-inflammatory cytokine, produced predominantly by peripheral immune cells but also by glia and some neuronal populations within the brain. Its signalling is mediated via the binding of IL-1α or IL-1β to the interleukin-1 type one receptor (IL-1RI. IL-1 plays a key role in inflammation-induced sickness behaviour, resulting in depressed locomotor activity, decreased exploration, reduced food and water intake and acute cognitive deficits. Conversely, IL-1 has also been suggested to facilitate hippocampal-dependent learning and memory: IL-1RI(-/- mice have been reported to show deficits on tasks of visuospatial learning and memory. We sought to investigate whether there is a generalised hippocampal deficit in IL-1RI(-/- animals. Therefore, in the current study we compared wildtype (WT mice to IL-1RI(-/- mice using a variety of hippocampal-dependent learning and memory tasks, as well as tests of anxiety and locomotor activity. We found no difference in performance of the IL-1RI(-/- mice compared to WT mice in a T-maze working memory task. In addition, the IL-1RI(-/- mice showed normal learning in various spatial reference memory tasks including the Y-maze and Morris mater maze, although there was a subtle deficit in choice behaviour in a spatial discrimination, beacon watermaze task. IL-1RI(-/- mice also showed normal memory for visuospatial context in the contextual fear conditioning paradigm. In the open field, IL-1RI(-/- mice showed a significant increase in distance travelled and rearing behaviour compared to the WT mice and in the elevated plus-maze spent more time in the open arms than did the WT animals. The data suggest that, contrary to prior studies, IL-1RI(-/- mice are not robustly impaired on hippocampal-dependent memory and learning but do display open field hyperactivity and decreased anxiety compared to WT mice. The results argue for a careful evaluation of the roles of endogenous IL-1 in hippocampal

Application of RI power sources to cardiac pacemakers and aftercare in its implantation

International Nuclear Information System (INIS)

Hori, Motokazu

1974-01-01

RI power sources have long life when they are implanted into human bodies together with cardiac pacemakers, as compared with e.g. mercury batteries. Therefore, the frequency of their replacement can be by far less. However, there are the problems of radiation protection, high cost, availability, etc. The following matters are described: The cardiac pacemaker and its power supply, implantation into human body, problems with patients and conventional power sources; the current state of RI power sources for cardiac pacemakers, including plutonium-238 RTG and 147 Pm and 3 H batteries; and problems with the RI power sources. (Mori, K.)

Rembrandt Kadrioru lossis / Jüri Hain

Index Scriptorium Estoniae

Hain, Jüri, 1941-

2000-01-01

Kadrioru lossi kuppelsaali tundmatu meistri laemaali maalimise ajalugu. Maali aluseks on Rembrandti maal "Diana suplus". Laemaal on maalitud Magdalena de Passe (1600-1638) vasegravüüri põhjal, mis on tehtud Rembrandti maalist. Rembrandt on lähtunud Antonio Tempesta (1555-1630) kahest gravüürist, viimane on lähtunud Otto van Veeni (1556-1629) maalist

Thermal characteristic of insulation for optimum design of RI transport package

International Nuclear Information System (INIS)

Lee, J. C.; Bang, K. S.; Seo, K. S.

2002-01-01

A package to transport the high level radioactive materials in required to withstand the hypothetical accident conditions as well as normal transport conditions according to IAEA and domestic regulations. The regulations require that the package should maintain the shielding, thermal and structural integrities to release no radioactive material. Thermal characteristics of insulations were evaluated and optimum insulation thickness was deduced for RI transport package. The package has a maximum capacity of 600 Curies for Ir-192 sealed source. The insulation thickness was decided with 10 mm of polyurethane form to maintain the thermal safety under fire accident condition. Thermal analysis was carried out for RI transport package, and it was shown that the thermal integrity of the package was maintained. The results obtained this study will be applied to a basic data for design of RI transport cask

Framework for applying RI-ISI methodology for Indian PHWRs

International Nuclear Information System (INIS)

Vinod, Gopika; Saraf, R.K.; Ghosh, A.K.; Kushwaha, H.S.

2006-01-01

Risk Informed In-Service Inspection (RI-ISI) aims at categorizing the components for In-Service inspection based on their contribution to Risk. For defining the contribution of risk from components, their failure probabilities and its subsequent effect on Core Damage Frequency (CDF) needs to be evaluated using Probabilistic Safety Assessment methodology. During the last several years, both the U.S. Nuclear Regulatory Commission (NRC) and the nuclear industry have recognized that Probabilistic Safety Assessment (PSA) has evolved to be more useful in supplementing traditional engineering approaches in reactor regulation. The paper highlights the various stages involved in applying RI-ISI and then compares the findings with existing ISI practices. (author)

The Impact Of State Policies On ACA Applications And Enrollment Among Low-Income Adults In Arkansas, Kentucky, And Texas.

Science.gov (United States)

Sommers, Benjamin D; Maylone, Bethany; Nguyen, Kevin H; Blendon, Robert J; Epstein, Arnold M

2015-06-01

States are taking variable approaches to the Affordable Care Act (ACA) Medicaid expansion, Marketplace design, enrollment outreach, and application assistance. We surveyed nearly 3,000 low-income adults in late 2014 to compare experiences in three states with markedly different policies: Kentucky, which expanded Medicaid, created a successful state Marketplace, and supported outreach efforts; Arkansas, which enacted the private option and a federal-state partnership Marketplace, but with legislative limitations on outreach; and Texas, which did not expand Medicaid and passed restrictions on navigators. We found that application rates, successful enrollment, and positive experiences with the ACA were highest in Kentucky, followed by Arkansas, with Texas performing worst. Limited awareness remains a critical barrier: Fewer than half of adults had heard some or a lot about the coverage expansions. Application assistance from navigators and others was the strongest predictor of enrollment, while Latino applicants were less likely than others to successfully enroll. Twice as many respondents felt that the ACA had helped them as hurt them (although the majority reported no direct impact), and advertising was strongly associated with perceptions of the law. State policy choices appeared to have had major impacts on enrollment experiences among low-income adults and their perceptions of the ACA. Project HOPE—The People-to-People Health Foundation, Inc.

Exercício físico e microRNAs: novas fronteiras na insuficiência cardíaca

Directory of Open Access Journals (Sweden)

Miguel Morita Fernandes-Silva

2012-05-01

Full Text Available Embora recentemente tenha sido questionado o impacto do exercício na sobrevida de pacientes com insuficiência cardíaca, o treinamento físico melhora a qualidade de vida, a capacidade funcional, a inflamação, a função autonômica e a função endotelial. Nos últimos anos, vem crescendo o interesse em um grupo de pequenos RNAs não codificadores de proteína chamados microRNAs. Estudos têm demonstrado que a expressão dessas moléculas se modifica em diversas condições patológicas, como a hipertrofia miocárdica, a isquemia miocárdica e a insuficiência cardíaca, e, quando ocorre melhora clínica, elas parecem se normalizar. Com o potencial de aplicabilidade prática, já foram identificados marcadores que poderão ser úteis na avaliação diagnóstica e prognóstica da insuficiência cardíaca, como o miR-423-5p. Além disso, resultados de estudos experimentais indicam haver possíveis efeitos terapêuticos dos microRNAs. Implicados na regulação da expressão genética durante o desenvolvimento fetal e no indivíduo adulto, os microRNAs aumentam ou diminuem no coração em resposta a estresse fisiológico, injúria ou sobrecarga hemodinâmica. Assim, o estudo do comportamento dessas moléculas no exercício físico vem trazendo informações importantes quanto aos efeitos dessa modalidade terapêutica e representa uma nova era no entendimento da insuficiência cardíaca. Esta revisão tem por objetivo integrar as evidências sobre microRNAs na insuficiência cardíaca com maior relevância no estudo do exercício físico.

Data of evolutionary structure change: 1DEAA-2RI1A [Confc[Archive

Lifescience Database Archive (English)

Full Text Available 1DEAA-2RI1A 1DEA 2RI1 A A -MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLG.../line> ASP CA 284 PHE CA 347 SER CA 228 1DEA... A 1DEAA ALVEMHKAGQVSFK 1DEA A 1DEAA GLU CA 160 ASP CA 224 VAL CA 284 1DEA

Comportamento dos quimiorreflexos central e periférico na insuficiência cardíaca Comportamiento de los quimiorreflejos central y periférico en la insuficiencia cardíaca Behavior of central and peripheral chemoreflexes in heart failure

Directory of Open Access Journals (Sweden)

Guilherme Veiga Guimarães

2011-02-01

Full Text Available A síndrome da insuficiência cardíaca (IC pode ser definida como via final de qualquer forma de doença cardíaca. Os reflexos cardiovasculares simpatoinibitórios como o reflexo arterial barorreceptor estão significativamente suprimidos na IC. Pacientes com IC apresentam maior ventilação para determinada carga de trabalho quando comparados a indivíduos normais. Esse fato gera baixa eficiência ventilatória e relaciona-se com maior ventilação relativa à produção de gás carbônico, que é um preditor de mau prognóstico, além de ser um fator limitante ao exercício. Há evidências de que o desequilíbrio autonômico contribua para a patogênese e a progressão da insuficiência cardíaca. Os quimiorreflexos são os principais mecanismos de controle e regulação das respostas ventilatórias às mudanças de concentração do oxigênio e gás carbônico arterial. A ativação do quimiorreflexo causa aumento da atividade simpática, frequência cardíaca, pressão arterial e volume minuto. No entanto, o aumento do volume minuto e da pressão arterial, pelo feedback negativo provocam inibição da resposta simpática à ativação do quimiorreflexo. Apesar das alterações funcionais dos reflexos, seu comportamento em condições normais e patológicas, especialmente sua contribuição para o estado simpatoexcitatório encontrado na IC, não tem sido amplamente estudado. Dessa forma, esta revisão tem por objetivo integrar os conhecimentos a respeito dos quimiorreflexos central e periférico na síndrome da insuficiência cardíaca, bem como esclarecer a influência da terapêutica medicamentosa da insuficiência cardíaca nos quimiorreflexos.El síndrome de insuficiencia cardíaca (IC puede ser definido como vía final de cualquier forma de enfermedad cardíaca. Los reflejos cardiovasculares simpáticoinhibitorios como el reflejo arterial barorreceptor están significativamente suprimidos en la IC. Pacientes con IC presentan mayor

Ühest avastamata illustreeritud raamatust / Jüri Hain

Index Scriptorium Estoniae

Hain, Jüri, 1941-

2011-01-01

Erick, Françoise. Heute / ill. Sergei Slastnikov. Tallinn : Tallinna Eesti Kirjastus-Ühisus, 1926. S. Slastnikovi puugravüüris illustratsioonidest, tema kunstialastest kirjutistest ja puugravüüri kasutuselevõtust eesti raamatukunstis

Narragansett, RI Lab--Office of Research and Development

Science.gov (United States)

The EPA-ORD laboratory in Narragansett, RI is a recognized leader in scientific knowledge and expertise concerning the ecology of oceans, estuaries, and water-sheds, and the effects of human activities on that ecology.

Estetoscópio digital como ferramenta inovadora no ensino da ausculta cardíaca

Directory of Open Access Journals (Sweden)

Claudio Tinoco Mesquita

2013-02-01

Full Text Available O exame físico cardiovascular, em particular a ausculta cardíaca, é uma das habilidades clínicas mais difíceis para os alunos durante seu treinamento médico. Estudos sugerem que o uso de tecnologias, como o estetoscópio digital, aumente a acurácia do exame clínico, entretanto, seu impacto no ensino da propedêutica da ausculta cardíaca em alunos de graduação de Medicina não é conhecido. O objetivo é demonstrar a utilidade do estetoscópio digital, em comparação com métodos tradicionais, como instrumento de ensino da ausculta cardíaca. Estudo de intervenção, longitudinal, controlado, unicêntrico e randomizado. Foram inscritos 38 alunos de medicina para um curso de semiologia cardiovascular com duração de oito semanas. Definiu-se um programa com aulas expositivas e à beira do leito nas enfermarias de Cardiologia. Nas aulas práticas, os alunos foram randomizados em dois grupos: 1 (n = 21 estetoscópio digital (Littmann® modelo 3200, 3M; e 2 (n = 17 estetoscópios convencionais. Foi realizada uma avaliação pré-treinamento, através de um teste utilizando o software Heart Sounds®, que foi repetida ao final do curso. As médias das avaliações foram comparadas pelo teste T pareado e não pareado. Observa-se que, ao final do curso, houve uma melhora significativamente maior no grupo que utilizou o estetoscópio digital (51,9% quando comparado ao grupo que utilizou o estetoscópio convencional (29,5%. Intervenções de curta duração para o ensino de semiologia cardíaca são capazes de contribuir de modo significativo para melhora da proficiência da identificação dos sons cardíacos. O uso do estetoscópio digital demonstrou ser um fator positivo no ensino dessas habilidades.

Comprehension of radiation for RI license

International Nuclear Information System (INIS)

Guk, Jin Sun

2005-08-01

This book starts with theoretical nuclear energy which explains technical terms such as nuclear physics and chemistry, RI and utilization of radiation, radiochemistry and radiation chemistry, radiation biology. It also explains radiation measurements technology including radiation detector and measurements radiation measurements circuit, measuring of energy spectrum. Radiation protection monitoring for radiation protection. It deals with nuclear law, enforcement regulation and ordinance.

Eduard Vääri : [Wiedemanni keeleauhinna laureaat 2001

Index Scriptorium Estoniae

2005-01-01

Sisu: Kogu elu eesti keele kaitsel : [F. J. Wiedemanni keeleauhinna vastuvõtmisel peetud kõne alusel] ; Laks, Meinhard. Liivi rannarahva lipp : [luuletus] = Livõ rńdarouv plaga / liivi keelde tõlkinud Eduard Vääri

The Ri chicken breed and livelihoods in North Vietnam: characterization and prospects

Directory of Open Access Journals (Sweden)

Pascal Leroy

2011-06-01

Full Text Available For the last twenty years, the consumption of poultry meat has boomed in Vietnam as in the rest of the developing world. Capital-intensive production has grown rapidly to satisfy this demand. Based on a few numbers of genetically uniform strains, these systems threaten biodiversity. In Vietnam, both rural and urban households still keep indigenous chickens as part of a diversified livelihood portfolio. In line with the national in situ conservation strategy, this study approached the context of local poultry keeping in two rural and one suburban districts of Northern Vietnam. It aimed at understanding households’ willingness, constraints and opportunities for practice improvement, including breeds’ management. As the Ri chicken constitutes the large majority of backyard flocks, two particular objectives of this study are the morpho-biometric characterisation of phenotypic diversity among individuals classified as Ri by farmers and an assessment of their productive potential. Chicken was found to hold a different place in livelihoods of the three districts with consequences on the management of genetic resources. The most favourable conditions for improvement of the Ri breed was found in the rural district of Luong-Son, due to market integration. In the more remote district of Ky-Son, living standards were lower and much would be gained from Ri conservation. Ri breed was the most threatened in the suburban Gia-Lam district, where poultry was a minor side-activity, lacking incentive for genetic management. From motives and constraints, tracks about breeding goals are suggested. Further considerations about conservation, improvement, market integration and livelihoods are proposed.

Improved performance of P3HT:PCBM solar cells by both anode modification and short-wavelength energy utilization using Tb(aca)3phen

International Nuclear Information System (INIS)

Zhuo Zu-Liang; Wang Yong-Sheng; He Da-Wei; Fu Ming

2014-01-01

The performance of P3HT:PCBM solar cells was improved by anode modification using spin-coated Tb(aca) 3 phen ultrathin films. The modification of the Tb(aca) 3 phen ultrathin film between the indium tin oxide (ITO) anode and the PE-DOT:PSS layer resulted in a maximum power conversion efficiency (PCE) of 2.99% compared to 2.66% for the reference device, which was due to the increase in the short-circuit current density (J sc ). The PCE improvement could be attributed to the short-wavelength energy utilization and the optimized morphology of the active layers. Tb(aca) 3 phen with its strong down-conversion luminescence properties is suitable for the P3HT:PCBM blend active layer, and the absorption region of the ternary blend films is extended into the near ultraviolet region. Furthermore, the crystallization and the surface morphology of P3HT:PCBM films were improved with the Tb(aca) 3 phen ultrathin film. The ultraviolent—visible absorption spectra, atomic force microscope (AFM), and X-ray diffraction (XRD) of the films were investigated. Both anode modification and short-wavelength energy utilization using Tb(aca) 3 phen in P3HT:PCBM solar cells led to about a 12% PCE increase. (interdisciplinary physics and related areas of science and technology)

Relação entre imagem adrenérgica cardíaca e teste ergométrico na insuficiência cardíaca Relación entre imagen adrenérgica cardíaca y ergometría en la insuficiencia cardíaca Relationship between cardiac adrenergic image and exercise testing in heart failure

Directory of Open Access Journals (Sweden)

Leandro Rocha Messias

2011-05-01

Full Text Available FUNDAMENTO: Na insuficiência cardíaca, o teste ergométrico (TE avalia capacidade funcional, um determinante de prognóstico. A cintilografia com I¹²³ MIBG mostra a ativação simpática cardíaca. OBJETIVO: Avaliar a associação entre as variáveis do TE e as alterações da cintilografia com I¹²³ MIBG. MÉTODOS: Foram submetidos 23 pacientes (FEVE 27%. Esses pacientes realizaram TE, onde foram analisadas: pressão arterial sistólica no pico do esforço (PASP, frequência cardíaca no pico do esforço (FCP, variação da pressão arterial sistólica intraesforço (Δ PAS, reserva cronotrópica e capacidade funcional em METs. Utilizaram-se para a análise estatística, o teste t de Student ou o teste U de Mann-Whitney, o coeficiente de Spearman e o coeficiente de regressão linear. RESULTADOS: A PASP (G1: 181,00 ± 28,01; G2: 153,27 ± 27,71, p = 0,027, a Δ PAS [G1: 64 (47,5-80,5; G2: 36 (25-47 mmHg, p = 0,015], a FCP (G1: 136,91 ± 19,66; G2: 118,45 ± 13,98 bpm, p = 0,018, a reserva cronotrópica (G1: 70,42 ± 17,94; G2: 49,47 ± 14,89%, p = 0,006 e a capacidade funcional [G1: 8,37 (6,47-10,27; G2: 4,42 (2,46-6,38 METs, p = 0,003] foram menores no G2. Houve correlação negativa entre taxa de Washout com PASP (r = -0,505, p = 0,014, Δ PAS (r = -0,493, p = 0,017 e capacidade funcional (r = -0,646, p = 0,001. Após regressão linear, PASP (r = -0,422, p = 0,016 e capacidade funcional (r = -0,804, p = 0,004 foram associadas com taxa de Washout. CONCLUSÃO: Em pacientes com insuficiência cardíaca, PASP e capacidade funcional foram as varáveis mais associadas com a taxa de Washout.FUNDAMENTOS: En la Insuficiencia Cardíaca, la Ergometría (Test Ergométrico - TE evalúa la capacidad funcional, un determinante de pronóstico. El centellograma con I¹²³ MIBG muestra la activación simpática cardíaca. OBJETIVO: Evaluar la asociación entre las variables del TE y las alteraciones del centellograma con I¹²³ MIBG. MÉTODOS: Se

Tüüri ava(sta)mas, kuid mitte ainult / Igor Garšnek

Index Scriptorium Estoniae

Garšnek, Igor, 1958-

2011-01-01

Kahest kontserdist Estonia kontserdisaalis - 4. märtsil ERSO ja Herbert Schuch (klaver) Olari Eltsi dirigeerimisel, kavas Tüüri Sümfoonia nr 8, Pärdi "Nekroloog" ja Ullmanni Klaverikontsert ning 10. märtsil Erkki-Sven Tüüri autorikontsert, kus esinesid Eesti Filharmoonia Kammerkoor ja Sinfonietta Riga Daniel Reussi juhatusel

Sonya Smith ja telenovela-äri / Tiina Lepiste

Index Scriptorium Estoniae

Lepiste, Tiina

2006-01-01

Telenovelade ärist ja fenomenist. Ka Venetsueela päritolu näitlejannast Sonya Smithist seriaalis "Armastuse jõud". Sama: Teleleht, 17. Jul. 2006, nr. 28, lk. 6-7 : ill pealkirjaga "Seebiäri vohab ja õitseb"

Mida me Tallinnas teinud oleme / Jüri Ratas

Index Scriptorium Estoniae

Ratas, Jüri, 1978-

2006-01-01

Tallinna linnapea Jüri Ratas annab ülevaate linnavalitsuse tegevusest esimese saja päeva jooksul. Linnavalitsuse tegevust hindavad Tallinna volikogu Isamaaliidu fraktsiooni esimees Toomas Tõniste, volikogu Reformierakonna esimees Keit Pentus ja volikogu sotsiaaldemokraatide fraktsiooni aseesimees Hannes Rumm

The role of the observational approach in RI planning: WAG 5 case study

International Nuclear Information System (INIS)

Brill, A.K.; Kuhaida, A.J. Jr.

1992-10-01

A Remedial Investigation (RI) Plan was developed for the Oak Ridge National Laboratory (ORNL) Waste Area Grouping (WAG) 5 in March 1988 and submitted to the Environmental Protection Agency (EPA) Region IV and the State of Tennessee for review and approval. The observational approach was evaluated by the ORNL Environmental Restoration (ER) Program and accepted by EPA as an accelerated and cost-effective approach to the RI/Feasibility Study (FS) process for remediation of WAG 5. The traditional approach used in preparing the 1988 RI Plan focused on data completeness, included a typical range of RI data-gathering activities for determining the nature and extent of contamination at WAG 5, and used multiple iterations of sampling activities to deal with uncertainties without consideration of potential deviations. In fall 1991, a revised Field Sampling Plan (FSP) was developed that used the observational approach to integrate site characterization with site remediation needs. This approach recognized the uncertainties of site characterization/remedial planning and developed contingency plans for dealing with them. The observational approach emphasizes data sufficiency to support remedial planning decisions for WAG 5

President vabastas Jüri Sakkarti kohtuniku ametist / Tanel Mazur

Index Scriptorium Estoniae

Mazur, Tanel, 1971-

2010-01-01

President Toomas Hendrik Ilves kirjutas 9. veebruaril 2010 alla otsusele vabastada Jüri Sakkart Viru Maakohtu kohtuniku ametist tema enda soovil. Kaitsepolitsei on J. Sakkarti kuriteokahtlustusega kinni pidanud

The importance of human FcgammaRI in mediating protection to malaria.

Directory of Open Access Journals (Sweden)

Richard S McIntosh

2007-05-01

Full Text Available The success of passive immunization suggests that antibody-based therapies will be effective at controlling malaria. We describe the development of fully human antibodies specific for Plasmodium falciparum by antibody repertoire cloning from phage display libraries generated from immune Gambian adults. Although these novel reagents bind with strong affinity to malaria parasites, it remains unclear if in vitro assays are predictive of functional immunity in humans, due to the lack of suitable animal models permissive for P. falciparum. A potentially useful solution described herein allows the antimalarial efficacy of human antibodies to be determined using rodent malaria parasites transgenic for P. falciparum antigens in mice also transgenic for human Fc-receptors. These human IgG1s cured animals of an otherwise lethal malaria infection, and protection was crucially dependent on human FcgammaRI. This important finding documents the capacity of FcgammaRI to mediate potent antimalaria immunity and supports the development of FcgammaRI-directed therapy for human malaria.

Evaluación de la respuesta a la terapia de resincronización cardíaca en un grupo de pacientes que asisten a un programa de falla cardíaca

Directory of Open Access Journals (Sweden)

Catalina Gallego Muñoz

2017-11-01

Full Text Available Resumen: Introducción: la terapia de resincronización cardiaca es una de las estrategias de tratamiento actuales para pacientes con insuficiencia cardiaca y función sistólica deprimida, que ha demostrado producir un alivio significativo en los síntomas, así como mejoría en la función ventricular izquierda y en la supervivencia a largo plazo. Objetivo: evaluar la respuesta a la terapia de resincronización cardíaca después de seis meses de seguimiento. Metodología: estudio observacional analítico de cohorte retrospectivo, con análisis anidado de casos y controles, en el que se incluyeron pacientes mayores de 18 años pertenecientes a una clínica de falla cardíaca y que fueran portadores de un dispositivo de resincronización cardíaca. Se realizó análisis univariado de las características clínicas y ecocardiográficas y posteriormente un análisis bivariado a las variables relacionadas con la respuesta a la terapia. Resultados: se incluyeron 92 pacientes con historia de falla cardíaca e indicación de terapia de resincronización; el 32,6% de los pacientes tenían cardiopatía isquémica y el 67,4% no isquémica, con una fracción de eyección promedio de 18,9%. Durante el seguimiento a los 6 primeros meses no se presentó ningún caso de muerte ni de trasplante cardíaco. Se definieron como respondedores el 47,8% de los pacientes, en tanto que el 52,2% restante fue clasificado como no respondedores. El porcentaje de pacientes que no requirieron hospitalizaciones luego de la terapia fue del 51,1%, y el 65,2% mejoró la clase funcional y 68,5% la fracción de eyección. Conclusión: en el 47,8% de la población estudiada se observó una respuesta a la terapia de resincronización cardiaca adecuada evaluada de forma combinada con parámetros clínicos y ecocardiográficos, hecho que se tradujo en una mejoría relevante en términos de fracción de eyección y clase funcional, además de menor número de hospitalizaciones por

Tartu kui märk / Jüri Talvet

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

1996-01-01

Ilmus algkujul hispaania keeles Sevillas Andaluusia Semiootikaassotsiatsiooni ajakirja Discurso Tartu semiootikakoolkonnale pühendatud erinumbris (nr. 8, 1993). Ilmunud ka kogumikus: Talvet, Jüri. Ameerika märkmeid, ehk, Kaemusi Eestist. Tartu : Ilmamaa, 2000, lk. 62-71, pealk.: Tartu vaim

77 FR 28253 - Safety Zone; America's Cup World Series, East Passage, Narragansett Bay, RI

Science.gov (United States)

2012-05-14

...-AA00 Safety Zone; America's Cup World Series, East Passage, Narragansett Bay, RI AGENCY: Coast Guard... navigable waters of the East Passage, Narragansett Bay, Rhode Island, during the America's Cup World Series... rulemaking (NPRM) entitled ``Safety Zones; America's Cup World Series, East Passage, Narragansett Bay, RI...

Current situation of RI's and radiation utilization in Japan

International Nuclear Information System (INIS)

1976-01-01

Usage of RIs and radiation is now extensive, for the improvement of industrial production techniques and also in medicine and agriculture. The current situation in Japan is described as follows: enterprises using RIs, circulation of RIs, the equipments provided with RIs in private enterprises, commercial RI, and radiation utilization, expenditures and sales related to RIs and radiation in mining and industries, and personnel. The number of places using RIs and radiation totaled about 3,200 (in 1975). The expenditures for RIs and radiation in private enterprises are about 17,500 million yen while sales are 20,800 million yen (both in fiscal 1974). The total number of personnel engaged in RI and radiation works is about 62,000. (Mori, K.)

Studying astrophysical reactions with low-energy RI beams at CRIB

Directory of Open Access Journals (Sweden)

Yamaguchi H.

2016-01-01

Full Text Available Studies on nuclear astrophysics, nuclear structure, and other interests have been performed using the radioactive-isotope (RI beams at the low-energy RI beam separator CRIB, operated by Center for Nuclear Study (CNS, the University of Tokyo. A typical measurement performed at CRIB is the elastic resonant scattering with the inverse kinematics. One recent experiment was on the α resonant scattering with 7Li and 7Be beams. This study is related to the astrophysical 7Li/7Be(α,γ reactions, important at hot p-p chain and νp-process in supernovae. There have also been measurements based on other experimental methods. The first THM measurement using an RI beam has been performed at CRIB, to study the 18F(p, α15O reaction at astrophysical energies via the three body reaction 2H(18F, α15On. The 18F(p, α 15O reaction rate is crucial to understand the 511-keV γ-ray production in nova explosion phenomena, and we successfully evaluated the reaction cross section at novae temperature and below experimentally for the first time.

Endurance test for IR rig for RI production assembly (test procedure)

International Nuclear Information System (INIS)

Chung, Heung June; Ryu, Jeong Soo

2000-08-01

This test procedure details the test loop, test method, and test procedure for pressure drop, vibration and endurance test of IR Rig for RI production. From the pressure drop test, the hydraulic design requirements of the capsule are verified. HANARO limit condition is checked and the compatibility with HANARO core is verified. From flow induced vibration test vibration frequency and displacement are investigated. The wear of IR Rig is investigated through endurance test, and these data are used to evaluate the expected wear at maximum resident time of the IR Rig for RI production

Tüüri autoriplaat on MIDEM-i auhinna nominent

Index Scriptorium Estoniae

2008-01-01

Muusikamessi MIDEM klassikalise muusika plaatide auhinnaõhtul on üheks preemia nominendiks Luciano Berio ja Krzysztof Penderecki kõrval Erkki-Sven Tüüri autoriplaat "Magma", messist 27.-31. jaan. Cannes'is Prantsusmaal

Äri domeeninimedega kogub Ameerikas hoogu / Margus Mihkels

Index Scriptorium Estoniae

Mihkels, Margus

2006-01-01

2005. aastal müüdi Ameerikas 5851 domeeninime ja nimeäri käive ulatus 29 miljoni USA dollarini. 2006. aasta esimese kolme kuu jooksul on ajakirja Domain Name Journal andmetel müüdud 1949 veebiaadressi 14,2 miljoni dollari eest

Literature as a nation's emotional memory / Jüri Talvet

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

1998-01-01

Bibliograafia, lk. 134-135. Autorist lk. 387. Juri Lotmani semiosfääri tõlgendamisest: "süntagmaatilised" struktuurid ja "perifeersed" kultuurid. Ka Friedebert Tuglase "Kalevipoja"-kriitikast ning Lydia Koidula ja Juhan Liivi luuletustest

Realidad de la cirugía cardíaca en la República Argentina. Registro CONAREC XVI

Directory of Open Access Journals (Sweden)

Diego M. Lowenstein Haber

2010-01-01

Full Text Available RESUMENIntroducciónLos dos grandes registros multicéntricos de cirugía cardíaca realizados en la Argentina,CONAREC y ESMUCICA, datan de más de 10 años. Considerando los avances médicosy quirúrgicos de la última década, surgió la necesidad de realizar un nuevo registronacional, prospectivo y multicéntrico para conocer las características, la evolución, lascomplicaciones y los predictores de mortalidad de los pacientes sometidos a cirugía cardíaca.ObjetivosConocer el perfil epidemiológico, la modalidad quirúrgica y la evolución posoperatoria de lospacientes sometidos a cirugía cardíaca en la Argentina.Material y métodosRegistro prospectivo, consecutivo y multicéntrico realizado en 49 centros cardioquirúrgicosde la República Argentina por residentes de cardiología. Se analizaron las características yla evolución de 2.553 pacientes sometidos a cirugía cardíaca entre septiembre de 2007 yoctubre de 2008: 1.465 (57,4% a cirugía coronaria, 359 (14,1% a reemplazo valvular aórtico,169 (6,6% a cirugía valvular mitral, 312 (12,2% a cirugía combinada coronariovalvular y248 (9,7% a otros procedimientos.ResultadosHubo predominio de hombres (74,9%; la edad promedio fue de 63 ± 11 años. La prevalenciade diabetes fue del 24,9%, la de hipertensión del 76,3% y la de insuficiencia cardíaca del17%. La disfunción ventricular moderada a grave prequirúrgica fue del 23,8% y el 19,8% delas cirugías fueron no programadas.En las cirugías coronarias, el 41,9% de ellas se realizaron sin circulación extracorpórea y seempleó puente mamario en el 89%.El 81,7% de las cirugías mitrales se indicaron por insuficiencia y el 62,6% de las aórticas,por estenosis. En estas cirugías se emplearon válvulas mecánicas en el 58% de los casos.La mediana de internación fue de 6 días. Se presentaron complicaciones mayores en el31,7% (del 25% en coronarios al 49,36% en combinados y la mortalidad global fue del 7,7%(del 4,3% en coronarios al 13

Undermining the ACA through the executive branch and federalism: what the Trump administration's approach to health reform means for older Americans.

Science.gov (United States)

Jones, David K; Gusmano, Michael K; Nadash, Pamela; Miller, Edward Alan

2018-04-12

The ACA has survived multiple existential threats in the legislative and judicial branches, including dozens of congressional attempts at repeal and two major Supreme Court cases. Even as it seems that the ACA is here to stay, what the law accomplishes is far from settled. The Trump administration is using executive powers to weaken the law, in many cases using the same powers that President Obama used to strengthen the effects of the reform. States have responded by seeking flexibility to pursue reforms, such as work requirements, that could not pass Congress and that were not allowed by the Obama administration. There is no indication that the ACA is imploding as President Trump has predicted and seems to desire, although these changes have a real and substantial impact on the lives of many Americans, including the near-elderly in unique ways.

Regeneración celular cardíaca

Directory of Open Access Journals (Sweden)

Jesús Herreros

2011-07-01

Full Text Available La terapia celular con células madre, como estrategia para regenerar tejidos dañados, es una de las áreas más prometedoras en el tratamiento de enfermedades con escasas o nulas expectativas de curación. La insuficiencia cardíaca, principalmente de origen isquémico, es una de las enfermedades que más se pueden beneficiar de esta estrategia. El objetivo es regenerar el músculo, reducir la apoptosis, aumentar la expresión del colágeno intersticial e inducir la generación de nuevos vasos. la terapia celular cardíaca ha sido propuesta con una gran variedad de células angiogénicas y miogénicas: mioblastos esqueléticos, células mononucleares y mesenquimales de médula ósea, progenitores endoteliales circulantes, células derivadas del estroma de la grasa o del endometrio, células mesoteliales y pluripotenciales (induced pluripotent stem cells [iPS]. las indicaciones incluyen a pacientes con miocardiopatía isquémica o dilatada, enfermedad de Chagas, insuficiencia mitral isquémica y miocardiopatía diabética. Los abordajes son quirúrgicos, con inyección periinfarto, intracoronario y endoventricular percutáneo. Los mecanismos de acción propuestos son la reducción del tamaño de la cicatriz del infarto, el aumento de la viabilidad miocárdica, la limitación del remodelado ventricular y los efectos paracrinos. Sin embargo, los resultados clínicos muestran sólo mejoras muy limitadas de la función sistólica y del remodelado ventricular. El desarrollo de estrategias que mejoren la supervivencia y la diferenciación celular deben ser prioritarias, tales como el preacondicionamiento con electroestimulación o la ingeniería tisular con el objetivo de desarrollar un miocardio bioartificial.

ANALISIS FAKTOR-FAKTOR YANG MEMENGARUHI TRANSFORMASI KAPABILITAS ORGANISASI DAN PERAN BADAN PEMERIKSA KEUANGAN RI

Directory of Open Access Journals (Sweden)

Agus Joko Pramono

2017-01-01

Full Text Available ABSTRACT This study is aimed to study the influencing factors of the Audit Board of Republic Indonesia’s roles and capabilities transformation to meet the national development goals. This study use a qualitative approach with Analytic Network Process (ANP method, to map out the interrelated factors of nodes within 3 clusters, which are the external, internal, and supporting factors. Focus Group Discussion (FGD was conducted to design a Framework Analysis. The participants of the FGD were BPK RI officials and its stakeholders including relevant external experts. The FGD has made a quantification framework as an ideal approach to use for data processing on software superdecisions. This process has brought about the priorities as follows: external stakeholder engagement, leadership and governance system, communication and the management of information system. The research has found out that the most significant and urgent factor is the concern of, and support from, the external stakeholders for BPK RI. Therefore, BPK RI has to design a strategy and communication program that can effectively improve the external support and concern. Keywords: Transformation, organizational capability, organizational roles, The Audit  Board of Indonesia, Analytic Network Process. ABSTRAK Kajian ini bertujuan untuk mengkaji faktor-faktor yang berpengaruh terhadap transformasi kapabilitas dan peran Badan Pemeriksa Keuangan Republik Indonesia. Kajian ini menggunakan pendekatan kualitatif dengan metode Analytic Network Process (ANP untuk mendapatkan hubungan antar node dalam 3 cluster (faktor eksternal, internal dan penunjang yang bersifat network. Framework analysis disusun melalui FGD para pakar dari eksternal dan internal BPK RI. Kuantifikasi framework dihasilkan dari FGD para pakar internal BPK RI. Olah data pada software superdecisions menghasilkan prioritas-prioritas sebagai berikut: faktor eksternal prioritasnya Stakeholders Engagement; faktor internal

77 FR 39395 - Special Local Regulations; Ocean State Tall Ships Festival 2012, Narragansett Bay, RI

Science.gov (United States)

2012-07-03

...-AA08 Special Local Regulations; Ocean State Tall Ships Festival 2012, Narragansett Bay, RI AGENCY... Tall Ships Festival 2012. DATES: This rule is effective from July 6, 2012 until July 10, 2012... ``Special Local Regulations: Ocean State Tall Ships Festival 2012, Narragansett Bay, RI'' in the Federal...

A comparative study of the FcepsilonRI molecule on human mast cell and basophil cell lines

DEFF Research Database (Denmark)

Jensen, Bettina Margrethe; Dissing, S; Skov, P S

2005-01-01

Mast cells and basophils express the high-affinity IgE receptor FcepsilonRI. We have analysed the human mast cell line LAD2 and four subclones of the basophil cell line KU812 in order to reveal possible differences concerning the FcepsilonRI surface regulation, anti-IgE-triggered activation......, FcepsilonRIalpha protein stability and the mRNA level of FcepsilonRIalpha-, beta- and the truncated beta-chain (beta(T)), and thereby determine the utility of these cell lines in investigations of the FcepsilonRI biology....

The predatory mite Neoseiulus womersleyi (Acari: Phytoseiidae) follows extracts of trails left by the two-spotted spider mite Tetranychus urticae (Acari: Tetranychidae).

Science.gov (United States)

Shinmen, Tsubasa; Yano, Shuichi; Osakabe, Mh

2010-10-01

As it walks, the two-spotted spider mite Tetranychus urticae Koch (Acari: Tetranychidae) spins a trail of silk threads, that is followed by the predatory mite, Neoseiulus womersleyi Schicha (Acari: Phytoseiidae). Starved adult female N. womersleyi followed T. urticae trails laid down by five T. urticae females but did not follow a trail of one T. urticae female, suggesting that the amount of spun threads and their chemical components should correlate positively with the number of T. urticae individuals. To examine whether chemical components of T. urticae trails are responsible for the predatory mite's trail following, we collected separate T. urticae threads from the exuviae and eggs, and then washed the threads with methanol to separate chemical components from physical attributes of the threads. Female N. womersleyi did not follow T. urticae trails that had been washed with methanol but contained physical residues, but they did follow the direction to which the methanol extracts of the T. urticae trails was applied. These results suggest that the predatory mite follows chemical, not physical, attributes of T. urticae trails.

Hidatidosis cardíaca primaria: quiste hidatídico en aurícula derecha con diseminación pulmonar

Directory of Open Access Journals (Sweden)

Christian Muñoz-Guijosa

2009-01-01

Full Text Available La hidatidosis es una enfermedad parasitaria producida por la larva del cestodo Echinococcus. El quiste hidatídico, la forma más habitual de presentación, es producida por la especie E. granulosus. la afectación cardíaca es muy rara, produciéndose en aproximadamente el 0,5–2% de los casos. El 65% de los casos de hidatidosis cardíaca se localizan en las cavidades izquierdas. Presentamos el caso de un paciente en el que la primera localización de la enfermedad fue la aurícula derecha (Ad, junto con diseminación pulmonar quística. La localización exclusiva en las cavidades cardíacas derechas y en la arteria pulmonar constituye una presentación clínica inusual. se ha revisado la bibliografía, prestando especial interés en la importancia de las técnicas de imagen disponibles en la actualidad para su diagnóstico, así como la necesidad de un tratamiento quirúrgico precoz para evitar sus posibles complicaciones.

Genome-wide analysis of wheat calcium ATPases and potential role of selected ACAs and ECAs in calcium stress.

Science.gov (United States)

Aslam, Roohi; Williams, Lorraine E; Bhatti, Muhammad Faraz; Virk, Nasar

2017-10-27

P 2 - type calcium ATPases (ACAs-auto inhibited calcium ATPases and ECAs-endoplasmic reticulum calcium ATPases) belong to the P- type ATPase family of active membrane transporters and are significantly involved in maintaining accurate levels of Ca 2+ , Mn 2+ and Zn 2+ in the cytosol as well as playing a very important role in stress signaling, stomatal opening and closing and pollen tube growth. Here we report the identification and possible role of some of these ATPases from wheat. In this study, ACA and ECA sequences of six species (belonging to Poaceae) were retrieved from different databases and a phylogenetic tree was constructed. A high degree of evolutionary relatedness was observed among P 2 sequences characterized in this study. Members of the respective groups from different plant species were observed to fall under the same clade. This pattern highlights the common ancestry of P 2- type calcium ATPases. Furthermore, qRT-PCR was used to analyse the expression of selected ACAs and ECAs from Triticum aestivum (wheat) under calcium toxicity and calcium deficiency. The data indicated that expression of ECAs is enhanced under calcium stress, suggesting possible roles of these ATPases in calcium homeostasis in wheat. Similarly, the expression of ACAs was significantly different in plants grown under calcium stress as compared to plants grown under control conditions. This gives clues to the role of ACAs in signal transduction during calcium stress in wheat. Here we concluded that wheat genome consists of nine P 2B and three P 2A -type calcium ATPases. Moreover, gene loss events in wheat ancestors lead to the loss of a particular homoeolog of a gene in wheat. To elaborate the role of these wheat ATPases, qRT-PCR was performed. The results indicated that when plants are exposed to calcium stress, both P 2A and P 2B gene expression get enhanced. This further gives clues about the possible role of these ATPases in wheat in calcium management. These findings can be

Assessment of the interactions between two predator mites of Tetranychus urticae (Acariformes: Tetranychidae in laboratory

Directory of Open Access Journals (Sweden)

Angelica María Argüelles

2013-01-01

Full Text Available Tetranychus urticae (Acari: Tetranychidae is one of the most important pests in ornamental cultures. Between the species most used for its control are Neoseilus sp. and Phytoseiulus persimilis (Acari: Phytoseiidae. Knowing the effectivity and ages of the prefers prey of each species of predator. In this search purposed the management of the plague through the use of combined releases, is necessary to evaluate that could occur between them with the prey when they act together. With this aim, we evaluated any situations. For one side was evaluated when a predator with a second predator with more density for the first predator. This situation was analyzed in presence and with absence of its prey. For other side, was evaluated the interactions of both predators are presents at the same density and with the prey. In the fist situation in presence of the prey was observe that increase the age of predator in minor density also increase the interference over the consumption of the high population’s predator over the prey. Moreover when decreased the T. urticae’s consumption increased the intraguild consumption. P. persimilis in absence of T. urticae and in presence of N. californicus approve a behavior of intraguild predation over all the ages of its cospecifics, while that N. californicus only consumed coespecific’s larvae in the phytofagous absence and in presence of  P. persimilis.  When both predators were in the same test at the same population’s density, was not observe a higher consumption of T. urticae that when each predator act for its way.

Nudging Leads Consumers In Colorado To Shop But Not Switch ACA Marketplace Plans.

Science.gov (United States)

Marzilli Ericson, Keith M; Kingsdale, Jon; Layton, Tim; Sacarny, Adam

2017-02-01

The Affordable Care Act (ACA) dramatically expanded the use of regulated marketplaces in health insurance, but consumers often fail to shop for plans during open enrollment periods. Typically these consumers are automatically reenrolled in their old plans, which potentially exposes them to unexpected increases in their insurance premiums and cost sharing. We conducted a randomized intervention to encourage enrollees in an ACA Marketplace to shop for plans. We tested the effect of letters and e-mails with personalized information about the savings on insurance premiums that they could realize from switching plans and the effect of generic communications that simply emphasized the possibility of saving. The personalized and generic messages both increased shopping on the Marketplace's website by 23 percent, but neither type of message had a significant effect on plan switching. These findings show that simple "nudges" with even generic information can promote shopping in health insurance marketplaces, but whether they can lead to switching remains an open question. Project HOPE—The People-to-People Health Foundation, Inc.

Relative Affordability of Health Insurance Premiums under CHIP Expansion Programs and the ACA.

Science.gov (United States)

Gresenz, Carole Roan; Laugesen, Miriam J; Yesus, Ambeshie; Escarce, José J

2011-10-01

Affordability is integral to the success of health care reforms aimed at ensuring universal access to health insurance coverage, and affordability determinations have major policy and practical consequences. This article describes factors that influenced the determination of affordability benchmarks and premium-contribution requirements for Children's Health Insurance Program (CHIP) expansions in three states that sought to universalize access to coverage for youth. It also compares subsidy levels developed in these states to the premium subsidy schedule under the Affordable Care Act (ACA) for health insurance plans purchased through an exchange. We find sizeable variability in premium-contribution requirements for children's coverage as a percentage of family income across the three states and in the progressivity and regressivity of the premium-contribution schedules developed. These findings underscore the ambiguity and subjectivity of affordability standards. Further, our analyses suggest that while the ACA increases the affordability of family coverage for families with incomes below 400 percent of the federal poverty level, the evolution of CHIP over the next five to ten years will continue to have significant implications for low-income families.

Genetic transformation of Begonia tuberhybrida by Ri rol genes.

Science.gov (United States)

Kiyokawa, S; Kikuchi, Y; Kamada, H; Harada, H

1996-04-01

We have developed an Agrobacterium -mediated transformation system for commercial Begonia species. The leaf explants of Begonia semperflorens, Begonia x hiemalis and B. tuberhybrida were inoculated with Agrobacterium tumefaciens LBA4404 harboring a binary vector pBI121 which contains rolA, B and C genes of an agropine type Ri plasmid (pRiA4b). Kanamycin resistant shoots of B. tuberhybrida were obtained on MS agar medium supplemented with 0.1 mg/l NAA, 0.5 mg/l BA, 500 mg/l claforan and 100 mg/l kanamycin. These shoots exhibited GUS activity and Southern analysis showed a single copy insertion into the genome. When the transgenic plants were transferred to soil, they displayed the phenotype specific to the transgenic plants by A. rhizogenes such as dwarfness, delay of flowering, and wrinkled leaves and petals.

EDF'S ''OMF-structures'' RI-ISI process: overview of the methodology, applications and comparison with the other existing RI-ISI initiatives

International Nuclear Information System (INIS)

Codron, P.; Lauriot, B.; Dubreuil-Chambardel, A.

2001-01-01

The OMF-Structures process has been developed by EDF in order to optimise the maintenance of piping components. The principles of the OMF-Structures are consistent with the RCM concepts in EDF's OMF process (applied to active components). Several applications of this process have been performed. This paper also presents several applications which have been performed, notably on the AFW, RHR, and HPSI/LPSI systems of EDF's 900 MW PWR plants. These applications led to propose optimised preventive maintenance programs for these systems. These updated preventive maintenance programs confirmed and justified a large proportion of existing maintenance, despite some inspection tasks were suppressed and some inspection tasks were added. Globally, these new programs guarantee a better safety level, insuring that preventive maintenance is applied on piping segments where risks are concentrated. A comparative evaluation of the OMF-Structures process with the EPRI and WOG/ASME RI-ISI methodologies has been performed. This comparison demonstrated the consistence of the OMF-Structures principles and selection criteria with the other RI-ISI processes. (author)

Design According to Liabilities: ACAS X and the Treatment of ADS-B Position Data

NARCIS (Netherlands)

Schebesta, H.; Contissa, Giuseppe; Sartor, Giovanni; Masutti, Anna; Paola, Tomasello; Taurino, Damiano

2015-01-01

This paper presents the results of the test application
of the Legal Case on ACAS X, the new generation airborne
collision avoidance system. The Legal Case is the novel
methodology, recently developed by the ALIAS project, to
address liability of innovative systems for aviation and

Äriühingu juhatuse liikme teenistusalane suhe : [bakalaureusetöö] / Anneli Kiljako ; Tartu Ülikool, õigusteaduskond ; juhendaja: Inge-Maret Orgo

Index Scriptorium Estoniae

Kiljako, Anneli

1999-01-01

Äriühingu juhatuse liikme teenistusalase suhtega seonduvad probleemid, äriühingu juhatuse liikme ja ja äriühingu vahelise lepingu sõlmimine, poolte õigused, kohustused, vastutus; juhtimislepingu lõppemine

A Study on the Representative Sampling Survey for Radionuclide Analysis of RI Waste

Energy Technology Data Exchange (ETDEWEB)

Jee, K. Y. [KAERI, Daejeon (Korea, Republic of); Kim, Juyoul; Jung, Gunhyo [FNC Tech. Co., Daejeon (Korea, Republic of)

2007-07-15

We developed a quantitative method for attaining a representative sample during sampling survey of RI waste. Considering a source, process, and type of RI waste, the method computes the number of sample, confidence interval, variance, and coefficient of variance. We also systematize the method of sampling survey logically and quantitatively. The result of this study can be applied to sampling survey of low- and intermediate-level waste generated from nuclear power plant during the transfer process to disposal facility.

Äriõigus 2006 : seaduste tekstid seisuga 01. 03. 2006 / koost. Andrus Lauren

Index Scriptorium Estoniae

2006-01-01

Kaanel sisu: Äriseadustik. Tulundusühistuseadus. TsÜS. Euroopa äriühingu (SE) määrus. Euroopa äriühingu (SE) määruse RS. SE töötajate kaasamise seadus. Euroopa ühistu (SCE) määrus. Euroopa ühistu (SCE) määruse RS. EMHÜ määrus. EMHÜ määruse RS. Konkurentsiseadus. Majandustegevuse registri seadus. Väärtpaberite keskregistri seadus. - Kommentaarid lk. 256-276

EHS & LCA assessment for 7-ACA synthesis

DEFF Research Database (Denmark)

Henderson, Richard K; Jiménez-González, Concepción; Preston, Chris

2008-01-01

and half the mass productivity of the enzymatic process. The chemical process uses more hazardous materials and solvents and requires about 25% more process energy than the enzymatic process. When accounting for the cradle-to-gate environmental life cycle, the chemical process has a larger overall...... environmental impact, mainly derived from the production of raw materials. In comparison to the enzyme-catalyzed process, the chemical process uses approximately 60% more energy, about 16% more mass (excluding water), has double the greenhouse gas (GHG) impact, and about 30% higher photochemical ozone creation......-to-gate methodology. The results compare the synthetic efficiency, environment, health, safety, and life cycle metrics for a mature chemical process and a more recent but less developed enzymatic process for making 7-ACA. The chemical process has a higher yield, but a significantly lower reaction mass efficiency...

Meie ühine mure on tervishoid / Jüri Ratas

Index Scriptorium Estoniae

Ratas, Jüri, 1978-

2008-01-01

Ilmunud ka: Den za Dnjom 1. veebr. lk. 18. Põhjarannik 18. jaan. 2008, lk. 2, Severnoje Poberezhje 18. jaan. 2008, lk. 2, Den za Dnjom 18. jaan. 2008, lk. 2. Riigikogu aseesimees Jüri Ratas tunneb muret Eesti elanike tervise pärast

Rahvus, "glokaalsus" ja eesti kirjandusdiskursus aastatuhandevahetusel / Jüri Talvet

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

2001-01-01

Bibliogr. joonealustes märkustes. Artikli aluseks on rahvusvahelisel konverentsil "Cultural Identity and Its Glocal Manifestations" (Joensuu, 14.-16. IX 2000) peetud ingliskeelne ettekanne. Artikkel on ilmunud ka kogumikus: Talvet, Jüri. Tõrjumatu äär. Tartu : Ilmamaa, 2005, lk. 31-45

Quantitative and clinical evaluation of whole CSF-axis RI image

International Nuclear Information System (INIS)

Tomono, Yuji; Nose, Tadao; Maki, Yutaka

1987-01-01

Whole CSF-axis RI scintigraphy was evaluated in 122 adult patients intending to know not only intracranial CSF flow but also the dynamics of whole CSF axis, particularly of spinal CSF flow. The change of radioactivity in several compartments was studied quantitatively with a dataprocessor on 18 cases with dilated ventricles, and more practically, clinical features and the findings of the films were comparatively studied on all the cases. The results were as follows: (1) Roughly speaking, the findings were classified into two types, i.e. a type with early RI movement to the intracranial CSF space and another with stagnation of radioactivity in spinal space till late stage, even 48 hours after RI injection (spinal stasis). (2) Although majority of the cases with spinal stasis did not show ventricular stasis, a shunt operation was not effective even when ventricular stasis was observed. (3) Spinal stasis tended to increase with aging, and was observed more frequently in cases with possible severe cerebral damage, as severe cerebrovascular disease and severe deterioration of mental activity. (4) The clearance of radioactivity of whole CSF-axis was remarkably delayed. It is considered that the spinal CSF flow is generated by intracranial CSF pulsation and, so, that spinal stasis shows the condition of lowered CSF flow by pulsation due to cerebral parenchymal damages. (author)

Aktsionäri infoõigus : [bakalaureusetöö] / Henri Parisalu ; Tartu Ülikool, õigusteaduskond ; juhendaja: Andres Vutt

Index Scriptorium Estoniae

Parisalu, Henri

2009-01-01

Aktsionäri infoõiguse eesmärkidest ja funktsioonidest, olemusest ja sisust mittebörsiühingutes ning börsiühingutes, siseriiklike ja rahvusvaheliste organisatsioonide mõjust aktsionäri infoõigusele

The Asia-RiCE activity with data cube

Science.gov (United States)

Oyoshi, K.; Sobue, S.; LE Toan, T.; Lam, N. D.

2017-12-01

The Asia-RiCE initiative (http://www.asia-rice.org) has been organized to enhance rice production estimates through the use of Earth observation satellites data, and seeks to ensure that Asian rice crops are appropriately represented within GEO Global Agriculture Monitoring (GEO-GLAM) to support FAO Agriculture Market Information System (FAO-AMIS). Asia-RiCE is composed of national teams that are actively contributing to the Crop Monitor for AMIS and developing technical demonstrations of rice crop monitoring activities using both Synthetic Aperture Radar (SAR) data (Radarsat-2 from 2013; Sentinel-1 and ALOS-2 from 2015.From 2016 after the successful rice crop area and growing estimation using SAR in a technical demonstration site (provincial level), wall-to-wall (national scale) excurse as phase 2 has been implemented in Vietnam and Indonesia in cooperation with ministry of agriculture and space agencies. This paper reports this year activity of 2017 accomplishment and way forward, especially for analysis ready data (ARD) definition of SAR to ingest to CEOS data cube to provide national scale service in Vietnam and Indonesia.

The erudite humility of the historian: the 'critical epistemology' of Georges Lantéri-Laura.

Science.gov (United States)

Basso Lorini, Elisabetta

2017-06-01

This paper analyses the historical and epistemological work of the French psychiatrist Georges Lantéri-Laura (1930-2004) within the context of the French 'tradition' of history and philosophy of sciences, with special reference to Georges Canguilhem and Michel Foucault. After an introduction devoted to a critical survey of the most recent works on the history and historiography of psychiatry in French, the paper outlines Lantéri-Laura's approach by focusing especially on the role played by the methodological concept of 'semiology' as regards the relation between medicine and psychiatry. The last part of the paper draws attention to the relation between the history and philosophy of psychiatry in light of Lantéri-Laura's 'critical epistemology'.

76 FR 59703 - Notice of Intent To Award Affordable Care Act (ACA) Funding, RFA-TP-08-001

Science.gov (United States)

2011-09-27

... as infectious disease outbreaks, and man-made and natural disasters. These activities are proposed by... costs.'' ACA and the Prevention and Public Health Fund make improving public health a priority with...

Perspectivas futuras de tratamiento en la insuficiencia cardíaca: del trasplante de células a la regeneración cardíaca

OpenAIRE

Prosper, F. (Felipe); Herreros, J. (Jesús); Barba, J. (Joaquín)

2004-01-01

En los últimos años hemos asistido a un interés creciente por el tratamiento de la insuficiencia cardíaca mediante el trasplante de células madre. Mientras que los estudios con células madre de músculo (mioblastos) se iniciaron hace más de 10 años, la posibilidad de que las células madre de la médula ósea tengan un enorme potencial de diferenciación y proliferación ha estimulado la investigación con otros tipos de células madre. Estos estudios experimentales han demost...

Development of new auxiliary basis functions of the Karlsruhe segmented contracted basis sets including diffuse basis functions (def2-SVPD, def2-TZVPPD, and def2-QVPPD) for RI-MP2 and RI-CC calculations.

Science.gov (United States)

Hellweg, Arnim; Rappoport, Dmitrij

2015-01-14

We report optimized auxiliary basis sets for use with the Karlsruhe segmented contracted basis sets including moderately diffuse basis functions (Rappoport and Furche, J. Chem. Phys., 2010, 133, 134105) in resolution-of-the-identity (RI) post-self-consistent field (post-SCF) computations for the elements H-Rn (except lanthanides). The errors of the RI approximation using optimized auxiliary basis sets are analyzed on a comprehensive test set of molecules containing the most common oxidation states of each element and do not exceed those of the corresponding unaugmented basis sets. During these studies an unsatisfying performance of the def2-SVP and def2-QZVPP auxiliary basis sets for Barium was found and improved sets are provided. We establish the versatility of the def2-SVPD, def2-TZVPPD, and def2-QZVPPD basis sets for RI-MP2 and RI-CC (coupled-cluster) energy and property calculations. The influence of diffuse basis functions on correlation energy, basis set superposition error, atomic electron affinity, dipole moments, and computational timings is evaluated at different levels of theory using benchmark sets and showcase examples.

Aiandusäri jahtumismärke ei ilmuta / Aive Herja

Index Scriptorium Estoniae

Herja, Aive

2008-01-01

Haljastus- ja aiandusäri praegu veel jahtumismärke ei ilmuta. Arvamust avaldavad aiandusettevõtete juhid. Lk. 28 intervjuu maastikuarhitektuurifirma Artes Terrae OÜ juhatuse liikme Sulev Nurmega "Sulev Nurme: maastikuarhitektuuri turg on kasvutrendis"

Ethical Challenges in a Complex World: Highlights of the 2005 ACA Code of Ethics

Science.gov (United States)

Kocet, Michael M.

2006-01-01

Being an effective counselor includes having knowledge of and the ability to integrate a code of ethics into one's professional practice. This article addresses some of the highlights of the changes in the 2005 ACA [American Counseling Association] Code of Ethics such as end-of-life issues, boundaries and relationships, and multicultural and…

Fyn kinase controls Fc{epsilon}RI receptor-operated calcium entry necessary for full degranulation in mast cells

Energy Technology Data Exchange (ETDEWEB)

Sanchez-Miranda, Elizabeth; Ibarra-Sanchez, Alfredo [Departamento de Farmacobiologia, Centro de Investigacion y de Estudios Avanzados (Cinvestav), Sede Sur, Calzada de los Tenorios 235, Col. Granjas Coapa, CP 14330 Mexico City (Mexico); Gonzalez-Espinosa, Claudia, E-mail: cgonzal@cinvestav.mx [Departamento de Farmacobiologia, Centro de Investigacion y de Estudios Avanzados (Cinvestav), Sede Sur, Calzada de los Tenorios 235, Col. Granjas Coapa, CP 14330 Mexico City (Mexico)

2010-01-22

IgE-antigen-dependent crosslinking of the high affinity IgE receptor (Fc{epsilon}RI) on mast cells leads to degranulation, leukotriene synthesis and cytokine production. Calcium (Ca{sup 2+}) mobilization is a sine qua non requisite for degranulation, allowing the rapid secretion of stored pro-inflammatory mediators responsible for allergy symptoms. Fyn is a Src-family kinase that positively controls Fc{epsilon}RI-induced mast cell degranulation. However, our understanding of the mechanism connecting Fyn activation to secretion of pre-synthesized mediators is very limited. We analyzed Fc{epsilon}RI-dependent Ca{sup 2+} mobilization in bone marrow-derived mast cells (BMMCs) differentiated from WT and Fyn -/- knock out mice. Fyn -/- BMMCs showed a marked defect in extracellular Ca{sup 2+} influx after Fc{epsilon}RI crosslinking but not after thapsigargin addition. High concentrations of Gadolinium (Gd{sup 3+}) partially blocked Fc{epsilon}RI-induced Ca{sup 2+} influx in WT cells but, in contrast, completely inhibited Ca{sup 2+} mobilization in Fyn -/- cells. Low concentrations of an inhibitor of the canonical transient receptor potential (TRPC) Ca{sup 2+} channels (2-aminoethoxyphenyl-borane, 2-APB) blocked Fc{epsilon}RI-induced maximal Ca{sup 2+} rise in WT but not in Fyn -/- cells. Ca{sup 2+} entry through Fyn-controlled, 2-APB sensitive channels was found to be important for full degranulation and IL-2 mRNA accumulation in WT cells. Immunoprecipitation assays showed that Fyn kinase interacts with TRPC 3/6/7 channels after IgE-antigen stimulation, but its association is not related to protein tyrosine phosphorylation. Results indicate Fyn kinase mediates the receptor-dependent activation of TRPC channels that contribute to degranulation in Fc{epsilon}RI-stimulated mast cells.

Muerte súbita por conmoción cardíaca (Commotio cordis asociada a miocardio no compactado

Directory of Open Access Journals (Sweden)

Analía Aquieri

2011-12-01

Full Text Available El miocardio no compactado es una rara miocardiopatía congénita caracterizada por la presencia de múltiples y prominentes trabeculaciones profundas en la pared ventricular que definen hendiduras comunicantes con el compartimiento ventricular principal. Es una entidad de baja incidencia y prevalencia que se diagnostica mediante estudios de imágenes como el ecocardiograma Doppler (ED, la tomografía computarizada multicorte (TCM y la resonancia magnética cardíaca (RMC. Puede ser asintomática o manifestarse mediante arritmias, insuficiencia cardíaca o eventos tromboembólicos. Se presenta el caso de un hombre de 33 años, asintomático, que durante la práctica deportiva sufre una conmoción cardíaca (commotio cordis que le produce un paro cardiorrespiratorio. El electrocardiograma mostró un ritmo de aleteo ventricular que requirió cardiodesfibrilación eléctrica. En un ED efectuado inicialmente no se observaron anormalidades significativas, pero otro ED, una TCM y una RMN obtenidos luego del alta, certificaron el hallazgo de miocardio no compactado aislado, descartando coronariopatía. Recibió tratamiento beta bloqueante y antiagregante y se discutió la colocación del cardiodesfibrilador implantable. Se plantea la fisiopatología de la asociación de estas dos infrecuentes y potencialmente letales afecciones.

Accommodation, accommodative convergence, and response AC/A ratios before and at the onset of myopia in children.

Science.gov (United States)

Gwiazda, Jane; Thorn, Frank; Held, Richard

2005-04-01

The purpose of this study was to investigate accommodation, accommodative convergence, and AC/A ratios before and at the onset of myopia in children. Refractive error, accommodation, and phorias were measured annually over a period of 3 years in 80 6- to 18-year-old children (mean age at first visit = 11.1 years), including 26 who acquired myopia of at least -0.50 D and 54 who remained emmetropic (-0.25 to + 0.75 D). Refraction was measured by noncycloplegic distance retinoscopy. Concomitant measures of accommodation and phorias were taken for letter targets at 4.0 m and 0.33 m using the Canon R-1 open field-of-view autorefractor with an attached motorized Risley prism and Maddox rod. The accommodation and phoria measurements were used to calculate response AC/A ratios. Compared with children who remained emmetropic, those who became myopic had elevated response AC/A ratios at 1 and 2 years before the onset of myopia, in addition to at onset and 1 year later (t's = -2.97 to -4.04, p accommodation. Accommodative convergence was significantly greater in myopes only at onset. These findings suggest that the abnormal oculomotor factors found before the onset of myopia may contribute to myopigenesis by producing hyperopic retinal defocus when a child is engaged in near-viewing tasks.

Jüriöö võit Saue Tammedele / Arvo Saal

Index Scriptorium Estoniae

Saal, Arvo

2008-01-01

Padisel toimunud 49. Jüriöö jooksul võitsid peaauhinna, Kalevipoja kuju kuuendat korda Saue Tammede spordiklubi esimese võistkonna orienteerujad Jürgen Einpalu, Kirti Rebane, Peeter Pihl, Viivi-Anne Soots ja Erkki Aadli

Jüri Pihl vstretilsja s Alfredom Perezom Rubalkaba / Kristina Kareva

Index Scriptorium Estoniae

Kareva, Kristina

2008-01-01

Siseminister Jüri Pihl kohtus Madridis Hispaania siseministri Alfredo Pérez Rubalcabaþga, et arutada politseiasutuste vahelist koostööd, küberkuritegevuse vastast võitlust ja Hispaania eesistumist Euroopa Liidus 2010. aastal

Acolhimento e sintomas de ansiedade em pacientes no pré-operatório de cirurgia cardíaca

Directory of Open Access Journals (Sweden)

Cinthia Calsinski Assis

2014-06-01

Full Text Available Trata-se de ensaio clínico randomizado, em que se objetivou comparar a frequência e intensidade de sintomas de ansiedade de pacientes em pré-operatório de cirurgia cardíaca que receberam acolhimento do enfermeiro ou do familiar ou os que não receberam nenhum tipo específico de acolhimento. A amostra foi constituída de 66 pacientes em pré-operatório de cirurgia cardíaca, que foram alocados em três grupos: acolhimento pelo enfermeiro, sem acolhimento específico e acolhimento pelo familiar. A ansiedade foi avaliada em dois momentos: antes e após a intervenção. O instrumento utilizado foi o construído e validado por Suriano, composto por 19 características definidoras do diagnóstico de enfermagem ansiedade. Observou-se que a redução dos sintomas de ansiedade foi maior no grupo que recebeu acolhimento dos familiares quando comparado aos outros dois grupos. Os resultados sugerem que o incentivo à participação de familiares pode contribuir para a redução de sintomas ansiosos em pacientes no pré-operatório de cirurgias cardíacas.

Transcription of Russian intonation ToRI, an interactive research tool and learning module on the internet

NARCIS (Netherlands)

Odé, C.

2008-01-01

This article discusses a new system for the Transcription of Russian Intonation, ToRI, on the Internet. Section 1 presents a general outline of the system. The terminology used in ToRI is defined in an online glossary, from which Section 2 gives the following examples: pitch accent and

Toward a conceptual understanding of acute cultural adaptation: A preliminary examination of ACA in female swimming

DEFF Research Database (Denmark)

Ryba, Tatiana; Haapanen, Saara; Mosek, Shwiko

2012-01-01

This paper considers a novel approach to researching adaptation in transnational athletes. The first part introduces a conceptualisation of acute cultural adaptation (ACA), which extends the current literature in sport psychology by offering original insights into mechanisms underpinning adaptive...

Monitorização intraoperatória com ecocardiografia transesofágica em cirurgia cardíaca

Directory of Open Access Journals (Sweden)

Carlos Galhardo Júnior

2011-08-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: Desde a sua introdução clínica na década de 1980, a ecocardiografia transesofágica (ETE intraoperatória tem representado um dos maiores avanços na anestesia cardíaca moderna. Trata-se de uma técnica semi-invasiva, que permite visualização direta e rápida da anatomia estrutural do coração e dos grandes vasos, além de contribuir para a avaliação hemodinâmica e funcional do sistema cardiovascular. Dessa maneira, tem-se tornado importante monitor para auxílio diagnóstico de patologias cardíacas e intervenções anestésico-cirúrgicas. O objetivo do artigo é realizar uma revisão abrangente sobre a utilização da ETE no intraoperatório de cirurgia cardíaca. CONTEÚDO: O artigo revisa alguns aspectos relacionados à física do ultrassom, as técnicas para a obtenção das imagens, os cortes ecocardiográficos mais utilizados no intraoperatório, as indicações e as principais aplicações clínicas do método, além das contraindicações e complicações. CONCLUSÕES: A ETE intraoperatória é um método de monitorização cardiovascular seguro e útil na formulação do plano cirúrgico, na orientação de intervenções hemodinâmicas e na avaliação imediata do resultado operatório. O anestesiologista, uma vez habilitado à utilização do método, amplia seu papel no contexto da medicina perioperatória, fornecendo informações clínicas imprescindíveis à condução do ato anestésico-cirúrgico em cirurgia cardíaca.

Reasoning and representation in RiTSE

International Nuclear Information System (INIS)

Epstein, S.A.

1987-01-01

RiTSE, the Reactor Trip Simulation Environment, is a frame and rule-base artificial intelligence (AI) application which aids nuclear power plant operators in determining if a proposed change in a state of a component or process causes safety systems to automatically shut the plant down. This paper stresses the software techniques used to implement the system. The authors demonstrate that prototypes and industrial strength systems can be built quickly and economically without expert system shells, and that integration of AI and database techniques create a novel programming paradigm

Concurrent inhibition of kit- and FcepsilonRI-mediated signaling: coordinated suppression of mast cell activation

DEFF Research Database (Denmark)

Jensen, Bettina M; Beaven, Michael A; Iwaki, Shoko

2008-01-01

Although primarily required for the growth, differentiation, and survival of mast cells, Kit ligand (stem cell factor) is also required for optimal antigen-mediated mast cell activation. Therefore, concurrent inhibition of Kit- and FcepsilonRI-mediated signaling would be an attractive approach...... characterized Kit inhibitor imatinib mesylate (imatinib). In contrast to imatinib, however, hypothemycin also effectively inhibited FcepsilonRI-mediated degranulation and cytokine production in addition to the potentiation of these responses via Kit. The effect of hypothemycin on Kit-mediated responses could...... be explained by its inhibition of Kit kinase activity, whereas the inhibitory effects on FcepsilonRI-dependent signaling were at the level of Btk activation. Because hypothemycin also significantly reduced the mouse passive cutaneous anaphylaxis response in vivo, these data provide proof of principle...

Intercropping Allium tuberosum Rottler ex Sprengel (Amaryllidaceae reduces Tetranychus urticae Koch (Acari: Tetranychidae populations in strawberry

Directory of Open Access Journals (Sweden)

Fernando Hata

2017-12-01

Efeito do cultivo consorciado de Allium tuberosum Rottlerex Sprengel(Amaryllidaceae em populações de Tetranychus urticae Koch (Acari: Tetranychidae em morangueiro Resumo. O ácaro-rajado, Tetranychus urticae Koch, é uma das mais importantes pragas em casas de vegetação no mundo. Foi avaliado o efeito do consórcio de cebolinha chinesa, cultivada sob as estruturas de madeira que suportam as sacolas para o cultivo de morangueiro (sistema suspenso, em duas casas de vegetação, entre novembro de 2016 e janeiro de 2017. Formas móveis e ovos de ácaros foram contabilizados em folhas de morangueiro. Para as avaliações, cinco plantas foram aleatoriamente selecionadas em cada parcela. Populações de ácaro-rajado em folhas de morangueiro foram avaliadas com lupa de bolso, com 10 x de aumento. Reduções foram observadas em três de oito avaliações de formas móveis de ácaro-rajado. Foram observadas reduções no número de ovos em uma avaliação. Tomando em consideração os dados de ácaros acumulados por dia, foi observado que o consórcio reduziu em 54% a população de ácaros. Por outro lado, o número de ovos não foi alterado.

Moskvast tuli Eestisse Hõbe-Jüri / Kristiina Davidjants

Index Scriptorium Estoniae

Davidjants, Kristiina, 1974-

2004-01-01

Moskvas lõppes XXVI rahvusvaheline filmifestival. Festivali programmi kuulus ka Renee Reinumäe, Jaak Kilmi noortefilm, mis sai žürii eripreemia, Hõbedase Püha Jüri. Peapreemia sai venelase Dmitri Meshijevi "Omad". Noorte lootustandvate režissööride programmis oli huvitav prantslase Christophe Honoré "Minu ema". Lisatud auhinnatute nimekiri ning nimekiri "Eesti filmide tähtsamaid autasusid"

Tüüri "Magma" kuuplaat. Pärt Saksa romaani kangelasena

Index Scriptorium Estoniae

2007-01-01

Erkki-Sven Tüüri heliplaat "Magma" oli kuuplaat nii BBC Music Magazine'is kui ka Gramophone'is. Saksa kirjanik Adam Thorpe avaldas romaani "Taktverschiebung" ("Taktimuutus"), mille peategelast, inglise heliloojat Jack Middletoni iseloomustatakse Arvo Pärdi suure austajana

Piiratud vastutusega äriühingu juhatuse liikme lojaalsuskohustus / Tuuve Tiivel

Index Scriptorium Estoniae

Tiivel, Tuuve, 1977-

2001-01-01

Huvide konfliktist aktsiaseltsi ja selle juhatuse liikme vahelise tehingu puhul, sellise tehingu kehtivusest, juhatuse liikme tasust, laenu- ja konkurentsikeelust ning konfidentsiaalsuskohustusest Eesti ja Ameerika Ühendriikide äriõiguses

Erkki-Sven Tüüri vioolakontsert "Illuminatio" / Igor Grašnek

Index Scriptorium Estoniae

Grašnek, Igor, 1958-

2009-01-01

Erkki-Sven Tüüri vioolakontserdist "Illuminatio", mis tuli Eestis esiettekandele 20. veebruaril Estonia kontserdisaalis ja mida esitasid vioolamängija Lars Anders Tomter ning ERSO Olari Eltsi dirigeerimisel

Complete Genome Sequence of the Yogurt Isolate Lactobacillus delbrueckii subsp. bulgaricus ACA-DC 87.

Science.gov (United States)

Alexandraki, Voula; Kazou, Maria; Pot, Bruno; Tsakalidou, Effie; Papadimitriou, Konstantinos

2017-08-24

Lactobacillus delbrueckii subsp. bulgaricus is widely used in the production of yogurt and cheese. In this study, we present the complete genome sequence of L. delbrueckii subsp. bulgaricus ACA-DC 87 isolated from traditional Greek yogurt. Whole-genome analysis may reveal desirable technological traits of the strain for dairy fermentations. Copyright © 2017 Alexandraki et al.

Construção e Validação do Questionário de Conhecimentos para Pacientes com Insuficiência Cardíaca

Directory of Open Access Journals (Sweden)

Christiani Decker Batista Bonin

2014-04-01

Full Text Available Fundamento: A ausência de instrumentos capazes de mensurar o nível de conhecimento de pacientes com insuficiência cardíaca sobre sua própria síndrome, participantes de programas de reabilitação, demonstra a carência de recomendações específicas a respeito da quantidade ou do conteúdo de informações necessárias. Objetivo: Construir e validar um questionário para avaliar o conhecimento sobre sua condição de pacientes portadores de insuficiência cardíaca participantes de programas de reabilitação cardíaca. Métodos: O instrumento foi construído com base no questionário de conhecimento para doença coronariana e aplicado em 96 pacientes com insuficiência cardíaca, com média de idade de 60,22 ± 11,6 anos, 64% homens. A reprodutibilidade foi obtida por meio do coeficiente de correlação intraclasse, utilizando-se as situações do método de teste-reteste. A consistência interna foi obtida pelo alfa de Cronbach e a validade do construto, pela análise fatorial exploratória. Resultados: A versão final do instrumento apresentou 19 questões dispostas em dez áreas de importância para a educação do paciente. O instrumento proposto apresentou um índice de clareza de 8,94 ± 0,83. O valor do coeficiente de correlação intraclasse foi de 0,856 e do alfa de Cronbach, 0,749. A análise fatorial revelou cinco fatores associados às áreas de conhecimento. Quando os escores finais foram comparados com as características da população, verificou-se que baixa escolaridade e baixa renda estão significativamente associadas a baixos escores de conhecimento. Conclusão: O instrumento possui índice de clareza satisfatório e de validade adequado, podendo ser utilizado para avaliar o conhecimento de pacientes com insuficiência cardíaca participantes de programas de reabilitação cardíaca.

Cell-Wall-Bound Proteinase of Lactobacillus delbrueckii subsp. lactis ACA-DC 178: Characterization and Specificity for β-Casein

Science.gov (United States)

Tsakalidou, E.; Anastasiou, R.; Vandenberghe, I.; van Beeumen, J.; Kalantzopoulos, G.

1999-01-01

Lactobacillus delbrueckii subsp. lactis ACA-DC 178, which was isolated from Greek Kasseri cheese, produces a cell-wall-bound proteinase. The proteinase was removed from the cell envelope by washing the cells with a Ca2+-free buffer. The crude proteinase extract shows its highest activity at pH 6.0 and 40°C. It is inhibited by phenylmethylsulfonyl fluoride, showing that the enzyme is a serine-type proteinase. Considering the substrate specificity, the enzyme is similar to the lactococcal PI-type proteinases, since it hydrolyzes β-casein mainly and α- and κ-caseins to a much lesser extent. The cell-wall-bound proteinase from L. delbrueckii subsp. lactis ACA-DC 178 liberates four main peptides from β-casein, which have been identified. PMID:10223997

Development of Biochips and Kits using RI Detection Technology for Life Science

International Nuclear Information System (INIS)

Park, Sang Hyun; Park, H. J.; Choi, S. M.

2010-04-01

Microarrays have recently become a precious research tool for proteomics and clinical investigation. In this study, we report on an efficient strategy for the detection of phosphorylation of a substrate catalyzed by kinase, using the radioisotope (RI) detection technique for a protein biochip. The biochip for the detection of phosphorylation using a RI facilitates the detection of phosphorylation with minimum amount of a sample by simple processes, compared with the conventional method using an antibody. It was more than 30 times detection sensitivity compared to conventional fluorescence detection technique. This technique does not employ the use of the blocking step which is commonly used in conventional methods to prevent non-specific binding. ELSA method was more than seven steps, but the usage of RI detection technique reduces the overall steps. Consequently, this technique is very simple, and considerably reduces the experiment time thus facilitating in an easy detection. Furthermore, it is highly sensitivity, thus facilitating the detection of even minor quantities of protein and rapid data analysis. It can be a useful tool for a high throughput screening in biological and medical research, and for studying protein-protein interactions

The Resilient Schools Consortium (RiSC): Linking Climate Literacy, Resilience Thinking and Service Learning

Science.gov (United States)

Branco, B. F.; Fano, E.; Adams, J.; Shon, L.; Zimmermann, A.; Sioux, H.; Gillis, A.

2017-12-01

Public schools and youth voices are largely absent from climate resilience planning and projects in New York City. Additionally, research shows that U.S. science teachers' understanding of climate science is lacking, hence there is not only an urgent need to train and support teachers on both the science and pedagogy of climate change, but to link climate literacy, resilience thinking and service learning in K-12 education. However, research on participation of students and teachers in authentic, civic-oriented experiences points to increased engagement and learning outcomes in science. The Resilient Schools Consortium (RiSC) Project will address all these needs through an afterschool program in six coastal Brooklyn schools that engages teachers and urban youth (grades 6-12), in school and community climate resilience assessment and project design. The RiSC climate curriculum, co-designed by New York City school teachers with Brooklyn College, the National Wildlife Federation, New York Sea Grant and the Science and Resilience Institute at Jamaica Bay, will begin by helping students to understand the difference between climate and weather. The curriculum makes extensive use of existing resources such as NOAA's Digital Coast and the Coastal Resilience Mapping Portal. Through a series of four modules over two school years, the six RiSC teams will; 1. explore and understand the human-induced drivers of climate change and, particularly, the significant climate and extreme weather related risks to their schools and surrounding communities; 2. complete a climate vulnerability assessment within the school and the community that is aligned to OneNYC - the city's resilience planning document; 3. design and execute a school-based resilience project; and 4. propose resilience guidelines for NYC Department of Education schools. At the end of each school year, the six RiSC teams will convene a RiSC summit with city officials and resilience practitioners to share ideas and

Radical SAM Enzymes in the Biosynthesis of Ribosomally Synthesized and Post-translationally Modified Peptides (RiPPs

Directory of Open Access Journals (Sweden)

Alhosna Benjdia

2017-11-01

Full Text Available Ribosomally-synthesized and post-translationally modified peptides (RiPPs are a large and diverse family of natural products. They possess interesting biological properties such as antibiotic or anticancer activities, making them attractive for therapeutic applications. In contrast to polyketides and non-ribosomal peptides, RiPPs derive from ribosomal peptides and are post-translationally modified by diverse enzyme families. Among them, the emerging superfamily of radical SAM enzymes has been shown to play a major role. These enzymes catalyze the formation of a wide range of post-translational modifications some of them having no counterparts in living systems or synthetic chemistry. The investigation of radical SAM enzymes has not only illuminated unprecedented strategies used by living systems to tailor peptides into complex natural products but has also allowed to uncover novel RiPP families. In this review, we summarize the current knowledge on radical SAM enzymes catalyzing RiPP post-translational modifications and discuss their mechanisms and growing importance notably in the context of the human microbiota.

Eesti estamp sisepaguluses : graafikatriennaal / Jüri Hain

Index Scriptorium Estoniae

Hain, Jüri, 1941-

2004-01-01

Graafikute grupinäitused G-galeriis (kuraator Loit Jõekalda, osalevad Vive Tolli, Vello Vinn, Silvi Liiva, Raul Meel, Mare Vint, Jüri Kass, Ülle Marks, Maria-Kristiina Ulas) kuni 25. IX, Aatriumi galeriis kuni 23. IX, Soome Instituudis kuni 30. IX, Vappu Thurlowi kureeritud näitus "Lähenemised" Estonia kontserdisaalis kuni 15. X, Virge Jõekalda näitus "Vaikus" Ungari Instituudis kuni 27. IX, Loit Jõekalda näitus "Must ja valge" galeriis 36 kuni 19. IX

134. Factores predictivos de transfusión sanguínea en cirugía cardíaca

Directory of Open Access Journals (Sweden)

G. Reyes

2012-04-01

Conclusiones: El uso de hemoderivados es frecuente en pacientes de bajo riesgo intervenidos de cirugía cardíaca. Una hemoglobina baja preoperatoria es el mayor factor de riesgo para la transfusión de hemoderivados.

Enfermedad cardíaca y embarazo

Directory of Open Access Journals (Sweden)

Ana G. Múnera-Echeverri

2018-01-01

Full Text Available Resumen: La enfermedad cardíaca complica el 1 al 4% de todos los embarazos. Durante la gestación ocurren cambios hemodinámicos importantes, que pueden llevar a la descompensación de la paciente con alteración estructural cardíaca previa. Sin embargo, la mayoría puede tener una gestación exitosa. Los pilares principales del manejo son el diagnóstico anatómico, la evaluación preconcepcional para intervenir antes de la gestación a las pacientes que lo requieran, la estratificación del riesgo materno-fetal, la optimización hemodinámica, y la administración de medicamentos seguros a las menores dosis posibles, la consejería genética y el pronóstico de la madre a largo plazo. Con base en lo anterior se diseña un plan de manejo, de acuerdo con la clasificación del riesgo materno y fetal, en el que define la frecuencia del seguimiento clínico, los métodos de imágenes y laboratorio, y el posible momento y vía del parto. El manejo es multidisciplinario y las pacientes con riesgo alto, posibilidad de deterioro hemodinámico o que requieran algún tipo de intervención deben ser remitidas en forma temprana a centros especializados con experiencia suficiente. Summary: Heart disease complicates 1 to 4% of all pregnancies. During pregnancy there are important hemodynamic changes that can lead to decompensation in a patient with previous cardiac structural alteration. However, the majority of patients can have a successful pregnancy. The primary keys to managing these patients are: knowledge of the Anatomy of the disease, evaluation before pregnancy, identify the maternal-fetal risk, optimize hemodynamically the patient, use safe drugs at the lowest doses, genetic counseling and prognosis of the mother in the long term. Based on these points, it is important to make a management plan based upon the maternal and fetal risk, defining the frequency of clinical follow-up, specifically outlining the clinical routines, diagnostic imaging

Consideration of the direction for improving RI-biomics information system for using big data in radiation field

Energy Technology Data Exchange (ETDEWEB)

Lee, Seung Hyun; Kim, Joo Yeon; Park, Tai Jin [Korean Association for Radiation Application, Seoul (Korea, Republic of); Lim, Young Khi [Dept. of Radiological Science, Gachon University, Incheon (Korea, Republic of)

2017-03-15

RI-Biomics is a fusion technology in radiation felds for evaluating in-vivo dynamics such as absorption, distribution, metabolism and excretion (RI-ADME) of new drugs and materials using radioisotopes and quantitative evaluation of their effcacy. RI-Biomics information is being provided by RIBio-Info developed as information system for distributing its information and three requirements for improving RIBio-Info system have been derived through reviewing recent big data trends in this study. Three requirements are defined as resource, technology and manpower, and some reviews for applying big data in RIBio-In system are suggested. Fist, applicable external big data have to be obtained, second, some infrastructures for realizing applying big data to be expanded, and finally, data scientists able to analyze large scale of information to be trained. Therefore, an original technology driven to analyze for atypical and large scale of data can be created and this stated technology can contribute to obtain a basis to create a new value in RI-Biomics feld.

Consideration of the direction for improving RI-biomics information system for using big data in radiation field

International Nuclear Information System (INIS)

Lee, Seung Hyun; Kim, Joo Yeon; Park, Tai Jin; Lim, Young Khi

2017-01-01

RI-Biomics is a fusion technology in radiation felds for evaluating in-vivo dynamics such as absorption, distribution, metabolism and excretion (RI-ADME) of new drugs and materials using radioisotopes and quantitative evaluation of their effcacy. RI-Biomics information is being provided by RIBio-Info developed as information system for distributing its information and three requirements for improving RIBio-Info system have been derived through reviewing recent big data trends in this study. Three requirements are defined as resource, technology and manpower, and some reviews for applying big data in RIBio-In system are suggested. Fist, applicable external big data have to be obtained, second, some infrastructures for realizing applying big data to be expanded, and finally, data scientists able to analyze large scale of information to be trained. Therefore, an original technology driven to analyze for atypical and large scale of data can be created and this stated technology can contribute to obtain a basis to create a new value in RI-Biomics feld

Purification and characterization of thermophilin T, a novel bacteriocin produced by Streptococcus thermophilus ACA-DC 0040

NARCIS (Netherlands)

Aktypis, A.; Kalantzopoulos, G.; Huis Veld,in't J.H.J.; Brink, B. ten

1998-01-01

ACA-DC 0040 produced an antimicrobial agent, which was named thermophilin T, active against several lactic acid bacteria strains of different species and food spoilage bacteria, such as Clostridium sporogenes C22/10 and Cl. tyrobutyricum NCDO-1754. The crude antimicrobial compound is sensitive to

Transcriptome Analysis of the Carmine Spider Mite, Tetranychus cinnabarinus (Boisduval, 1867 (Acari: Tetranychidae, and Its Response to β-Sitosterol

Directory of Open Access Journals (Sweden)

Chunya Bu

2015-01-01

Full Text Available Tetranychus cinnabarinus (Acari: Tetranychidae is a worldwide polyphagous agricultural pest that has the title of resistance champion among arthropods. We reported previously the identification of the acaricidal compound β-sitosterol from Mentha piperita and Inula japonica. However, the acaricidal mechanism of β-sitosterol is unclear. Due to the limited genetic research carried out, we de novo assembled the transcriptome of T. cinnabarinus using Illumina sequencing and conducted a differential expression analysis of control and β-sitosterol-treated mites. In total, we obtained >5.4 G high-quality bases for each sample with unprecedented sequencing depth and assembled them into 22,941 unigenes. We identified 617 xenobiotic metabolism-related genes involved in detoxification, binding, and transporting of xenobiotics. A highly expanded xenobiotic metabolic system was found in mites. T. cinnabarinus detoxification genes—including carboxyl/cholinesterase and ABC transporter class C—were upregulated after β-sitosterol treatment. Defense-related proteins, such as Toll-like receptor, legumain, and serine proteases, were also activated. Furthermore, other important genes—such as the chloride channel protein, cytochrome b, carboxypeptidase, peritrophic membrane chitin binding protein, and calphostin—may also play important roles in mites’ response to β-sitosterol. Our results demonstrate that high-throughput-omics tool facilitates identification of xenobiotic metabolism-related genes and illustration of the acaricidal mechanisms of β-sitosterol.

Dating the Bibong-ri Neolithic site in Korea: Excavating the oldest ancient boat

International Nuclear Information System (INIS)

Park, Gyujun; Kim, Jong-Chan; Youn, Minyoung; Yun, Chongcheol; Kang, Jin; Song, Yong-Mi; Song, Su-Jin; Noh, Hye-Jin; Kim, Do-Kyun; Im, Hack-Jong

2010-01-01

The remains of an ancient wooden boat were unearthed at the Bibong-ri shell mound site. The site was located at Bibong-ri, Bugog-myeon, Changnyeong-gun, Gyeongsangnam-do in South Korea. A substantial fragment of the vessel was discovered in the lowest layer of the site. We collected 17 samples of charcoal and wood from pebble, sand, and shell layers. Sample preparation extracted the carbon from each sample material and converted it into graphite for AMS radiocarbon dating. Radiocarbon dates of the samples indicate that they belong to the Neolithic period and that the boat dates from ca. 5700 BC. To this point, the oldest known boat in the world has been a wooden boat dating from ca. 5500 BC in China. Other ancient boats from around the world include a logboat dating from ca. 3600 BC in Japan and a fleet of wooden boats dating from ca. 3000 BC in Egypt. The Bibong-ri boat is the first boat from the Neolithic period ever found in South Korea and must represent one of the world's oldest known boats.

Muusikaäri otsib uusi müügiideid / Kuldar Kullasepp

Index Scriptorium Estoniae

Kullasepp, Kuldar, 1980-

2009-01-01

IT- valdkonna muusiakäri uutest võimalustest. USA firmast Rdio, Niklas Zennströmi ja Janus Friisi pakutavast tensuest, millega pakutakse muusikat nii arvuti kui ka mobiiltelefoniaskutajatele pakkuda. Digitaalsetest plaadipoodidest Eestis

USA kahepaiksest mängust / Jüri Lina

Index Scriptorium Estoniae

Lina, Jüri, 1949-

2000-01-01

Sama artikkel on ilmunud ka Eesti 2000 : sõltumatu almanahh ühiskonna ja vaimuelu küsimustes nr. 4 ja nr. 6. Autori väitel on USA muu hulgas huvitatud maakera rahvastiku drastilisest vähendamisest, seepärast ongi pärast Teist maailmasõda kunstlikult lõkkele puhutud sadu sõjalisi konflikte. Lisatud Jüri Lina lühielulugu lk. 23

Ääremärkused diagnoosiks : Imagosfäär tulgu I = Remarks for diagnosis : Imagosphere Come I / Jüri Soolep

Index Scriptorium Estoniae

Soolep, Jüri, 1962-

2008-01-01

Imagosfääri empiiriline kehtestumine: meedia, Gutenbergi galaktika, isiklik imagosfäär. Imagosfääri teoreetiline konstitutsioon: simulaakrumid ja hüperreaalsus. Imagosfääri praktiline realisatsioon: Putini Venemaa. Artikkel põhineb Eesti Kunstiakadeemias 2007. a. sügissemestril peetud loengukursusel "Linnaehituse nüüdisaegsed probleemid". Bibliograafia lk. 38

AHP 10: "I, Ya ri a bsod, Am a Dog": The Life and Music of a Tibetan Mendicant Singer

Directory of Open Access Journals (Sweden)

Skal dbang skyid སྐལ་དབང་སྐྱིད།

2011-06-01

Full Text Available The life and music of Ya ri A bsod, a Tibetan composer and singer who lived in the early twentieth century, is described. Ya ri A bsod wandered through Tibetan nomad areas where contemporary Qinghai, Gansu, and Sichuan provinces meet in China. Texts and transcribed melodies of Ya ri A bsod songs are presented. These songs are contextualized in terms of their contemporary transmission, and the historical and autobiographical circumstances of their composition.

RI cisternography and CT cisternography in chronic subdural effusion in infancy

Energy Technology Data Exchange (ETDEWEB)

Fujiwara, K.; Hayakawa, I. (Bokuto Municipal Hospital of Metropolitan, Tokyo (Japan))

1980-10-01

Differential diagnosis has been made more accurately between subdural and subarachnoid effusions in infancy since the introduction of the CT scan. We have four cases where In-DTPA (lmCi) and Metrizamide (5 ml x 170 mgl/dl) were given intrathecally at the same time. These dynamics were followed at intervals of 3, 6, 24, and 48 hours, and the diagnosis of chronic subdural effusion (or hematoma) was made at the time of surgery. The findings of both cisternographies were analyzed in these 4 cases. The dynamics of the two materials in the CSF space were almost the same. Comparing the two materials, CT cisternography delineates the anatomical structures of CSF pathways more clearly and accurately. Cerebral sulci and sylvian fissures were well defined with metrizamide at 3 and/or 6 h, but the subdural space was nonfilling. The diagnosis of the CSF block is significant in determining operative indications. RI cisternography seems to be the better method of detecting abnormal findings regarding convexity flow, especially the asymmetry of cerebral convexity. However, the asymmetrical convexity flow as determining by RI at 24 and/or 48 h corresponds quite closely to asymmetrical sylvian-fissure filling by metrizamide at 3 and/or 6 h. It has been concluded that metrizamide CT cisternography can replace some parts of RI cisternography in studying chronic subdural effusion in infancy.

La anemia ferropénica como presentación de enfermedad celíaca subclínica en una población argentina

OpenAIRE

J.S. Lasa; P. Olivera; L. Soifer; R. Moore

2017-01-01

Introducción: Existe una extensa heterogeneidad en los reportes de la prevalencia de enfermedad celíaca en el contexto de la anemia ferropénica. Objetivo: Determinar la prevalencia de enfermedad celíaca en pacientes con anemia ferropénica. Materiales y métodos: Pacientes adultos con anemia ferropénica fueron reclutados para realizarse una endoscopia digestiva alta con biopsia duodenal. Se reclutaron asimismo voluntarios sanos de la comunidad como controles. Resultados: Se reclutó a 1...

76 FR 41501 - Notice of Intent To Award Affordable Care Act (ACA) Funding, EH09-907

Science.gov (United States)

2011-07-14

... network expansion and enhancement. Funding is appropriated under the Affordable Care Act (Pub. L. 111-148... Intent To Award Affordable Care Act (ACA) Funding, EH09-907 AGENCY: Centers for Disease Control and... in their FY 2011 applications submitted under funding opportunity EH09-907, ``National Environmental...

Experiências de quase morte em parada cardíaca: implicações para o conceito de mente não local

Directory of Open Access Journals (Sweden)

Natalie Trent-Von Haesler

2013-01-01

Full Text Available CONTEXTO: Experiências de quase morte (EQM são experiências vívidas, realísticas, que frequentemente promovem mudanças profundas na vida de pessoas que estiveram fisiológica ou psicologicamente próximas da morte. As EQM por vezes ocorrem durante uma parada cardíaca, na ausência de atividade cerebral detectável. OBJETIVO: Revisar os estudos prospectivos de EQM induzidas por paradas cardíacas e examinar as implicações desses estudos para o conceito de mente não local. MÉTODO: PubMed foi a principal base de dados utilizada para esta revisão. Os termos-chave da busca incluíram "parada cardíaca", "experiências de quase morte", "fisiologia da experiência de quase morte" e "experiências fora do corpo verídicas". RESULTADOS: Vários estudos prospectivos mostram incidência média de 10% a 20% de EQM induzidas por paradas cardíacas, independentemente de aspectos sociodemográficos, sexo, religião ou quaisquer parâmetros médicos, fisiológicos ou farmacológicos consistentes. Pessoas que passaram por EQM são mais propensas a mudanças de vida positivas que podem durar muitos anos após a experiência do que aquelas que não a tiveram. CONCLUSÕES: As teorias fisicalistas da mente não são capazes de explicar como pessoas que tiveram EQM podem vivenciar - enquanto seus corações estão parados e sua atividade cerebral aparentemente ausente - pensamentos vívidos e complexos e adquirir informações verídicas a respeito de objetos ou eventos distantes de seus corpos. As EQM em paradas cardíacas sugerem que a mente é não local, isto é, não é gerada pelo cérebro e não está confinada a ele ou ao corpo.

Layout Design of Human-Machine Interaction Interface of Cabin Based on Cognitive Ergonomics and GA-ACA

Directory of Open Access Journals (Sweden)

Li Deng

2016-01-01

Full Text Available In order to consider the psychological cognitive characteristics affecting operating comfort and realize the automatic layout design, cognitive ergonomics and GA-ACA (genetic algorithm and ant colony algorithm were introduced into the layout design of human-machine interaction interface. First, from the perspective of cognitive psychology, according to the information processing process, the cognitive model of human-machine interaction interface was established. Then, the human cognitive characteristics were analyzed, and the layout principles of human-machine interaction interface were summarized as the constraints in layout design. Again, the expression form of fitness function, pheromone, and heuristic information for the layout optimization of cabin was studied. The layout design model of human-machine interaction interface was established based on GA-ACA. At last, a layout design system was developed based on this model. For validation, the human-machine interaction interface layout design of drilling rig control room was taken as an example, and the optimization result showed the feasibility and effectiveness of the proposed method.

Layout Design of Human-Machine Interaction Interface of Cabin Based on Cognitive Ergonomics and GA-ACA.

Science.gov (United States)

Deng, Li; Wang, Guohua; Yu, Suihuai

2016-01-01

In order to consider the psychological cognitive characteristics affecting operating comfort and realize the automatic layout design, cognitive ergonomics and GA-ACA (genetic algorithm and ant colony algorithm) were introduced into the layout design of human-machine interaction interface. First, from the perspective of cognitive psychology, according to the information processing process, the cognitive model of human-machine interaction interface was established. Then, the human cognitive characteristics were analyzed, and the layout principles of human-machine interaction interface were summarized as the constraints in layout design. Again, the expression form of fitness function, pheromone, and heuristic information for the layout optimization of cabin was studied. The layout design model of human-machine interaction interface was established based on GA-ACA. At last, a layout design system was developed based on this model. For validation, the human-machine interaction interface layout design of drilling rig control room was taken as an example, and the optimization result showed the feasibility and effectiveness of the proposed method.

RFI/RI work plan for the Road A Chemical Basin 904-111G

International Nuclear Information System (INIS)

Kmetz, T.F.

2000-01-01

This Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI)/Remedial Investigation (RI) Work Plan has been prepared for the Road A Chemical Basin Operable Unit (RdACB OU) (904-111G). This unit is subject to the requirements of both RCRA and the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). This Work Plan presents the initial evaluation of existing unit data, applicable background data, the regulatory framework for the unit investigation, and the evaluations and decisions made during the determination of the scope and objectives of the planned Remedial Investigation/Feasibility Study (RI/FS) activities

RFI/RI work plan for the Road A Chemical Basin 904-111G

Energy Technology Data Exchange (ETDEWEB)

Kmetz, T.F.

2000-03-07

This Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI)/Remedial Investigation (RI) Work Plan has been prepared for the Road A Chemical Basin Operable Unit (RdACB OU) (904-111G). This unit is subject to the requirements of both RCRA and the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). This Work Plan presents the initial evaluation of existing unit data, applicable background data, the regulatory framework for the unit investigation, and the evaluations and decisions made during the determination of the scope and objectives of the planned Remedial Investigation/Feasibility Study (RI/FS) activities.

The value of RI scintigraphy and angiography in small intestinal bleeding; Report of eight cases

Energy Technology Data Exchange (ETDEWEB)

Kurosawa, Susumu; Kuwata, Hajime; Kushibiki, Kyoko; Akimoto, Kimihiko; Hashimoto, Toshiyuki; Kojima, Toshiya (Showa General Hospital, Kodaira, Tokyo (Japan))

1991-07-01

We retrospectively reviewed eight cases of small intestinal bleeding and assessed the value of RI scintigraphy and angiography in diagnosing the bleeding site. The patients' average age was 56.2 years. Chief complaint was melena of variable degree. In most cases neither upper endoscopy nor colonoscopy was diagnostic. RI scientigraphy (Tc-99 labeled human serum albumin) showed 75% of positive rate whereas angiography showed 66.7% (4/6) of positive rate. All four cases of leiomyosarcoma and leiomyoma demonstrated hypervascular stain and/or extra-vasation in angiography whereas RI scintigraphy failed to detect active gastrointestinal bleeding in 2 of the 4 cases. Therefore angiography was considered useful for the detection of bleeding from leiomyoma and leiomyosarcoma which are often hypervascular. Scintigraphy is thought of most value in the demonstration of small amount of bleeding with minimum vascular abnormality. (author).

Performance on the RI-48 Cued Recall Test Best Predicts Conversion to Dementia at the 5- and 10-Year Follow-Ups

Directory of Open Access Journals (Sweden)

Bernard Hanseeuw

2011-08-01

Full Text Available Background: TheRI-48 cued recall test was devised to discriminate between healthy elderly and patients with mild cognitive impairment who are at risk of developing Alzheimer’s disease (AD. However, no long-term follow-up studies have been conducted using this test. Methods: We analyzed the predictive power of the RI-48 test for determining the patients who will convert to AD dementia within the decade after testing. During 10 years, we followed up 40 non-demented patients who attended our Memory Clinic and underwent complete neuropsychological evaluation including the RI-48. Results: Of the 40 patients, 21 developed dementia (converters, CO and 19 remained stable patients (SP. Of the tests performed at inclusion, only the RI-48 (p Conclusion: The RI-48 had the best overall diagnostic accuracy at 5- and at 10-year follow-ups.

Reducing Young Adults' Health Care Spending through the ACA Expansion of Dependent Coverage.

Science.gov (United States)

Chen, Jie; Vargas-Bustamante, Arturo; Novak, Priscilla

2017-10-01

To estimate health care expenditure trends among young adults ages 19-25 before and after the 2010 implementation of the Affordable Care Act (ACA) provision that extended eligibility for dependent private health insurance coverage. Nationally representative Medical Expenditure Panel Survey data from 2008 to 2012. We conducted repeated cross-sectional analyses and employed a difference-in-differences quantile regression model to estimate health care expenditure trends among young adults ages 19-25 (the treatment group) and ages 27-29 (the control group). Our results show that the treatment group had 14 percent lower overall health care expenditures and 21 percent lower out-of-pocket payments compared with the control group in 2011-2012. The overall reduction in health care expenditures among young adults ages 19-25 in years 2011-2012 was more significant at the higher end of the health care expenditure distribution. Young adults ages 19-25 had significantly higher emergency department costs at the 10th percentile in 2011-2012. Differences in the trends of costs of private health insurance and doctor visits are not statistically significant. Increased health insurance enrollment as a consequence of the ACA provision for dependent coverage has successfully reduced spending and catastrophic expenditures, providing financial protections for young adults. © Health Research and Educational Trust.

77 FR 39516 - Notice of a Public Meeting of the Advisory Committee on Apprenticeship (ACA)

Science.gov (United States)

2012-07-03

... ACA are open to the public. Time and Date: The meeting will begin at approximately 1:30 p.m. Eastern Daylight Savings Time on Wednesday, August 1, 2012, and continues until approximately 5:00 p.m. The meeting will reconvene on Thursday, August 2, 2012, at approximately 9:00 a.m. Eastern Daylight Savings Time...

Comparison of cerebrospinal fluid dynamics studied by computed tomography (CT) and radioisotope (RI) cisternography

International Nuclear Information System (INIS)

Tamaki, N.; Kanazawa, Y.; Asada, M.; Kusunoki, T.; Matsumoto, S.

1978-01-01

CT and RI cisternography were done on 55 cases with normal and abnormal CSF circulation. Of 19 cases in which both studies were done, 14 cases disclosed a good correspondence. The remaining five cases showed no correspondence because of technical failure. Analyzing the results, CT cisternography demonstrates pathology of the CSF dynamics in a more precise and quantitative manner than RI cisternography does. Metrizamide CT cisternography will soon be the most reliable method of investigation for the evaluation of the CSF kinetics. (orig.) [de

BV RI CCD photometry of 361,281 objects in the field of M 31

Science.gov (United States)

Magnier, E. A.; Lewin, W. H. G.; Van Paradijs, J.; Hasinger, G.; Jain, A.; Pietsch, W.; Truemper, J.

1992-01-01

Deep BV RI CCD photometry was performed on a 1 sq deg region of M 31. A catalog of photometry and astrometry of a total of 361,281 stars is presented, with typical completion limits of BV RI = (22.3, 22.2, 22.2, 20.9). Photometric accuracy is about 2 percent at V = 19. This catalog allows detailed studies of stellar populations and reddening. The data are currently being used to assist in finding the optical counterparts of Einstein and ROSAT X-ray sources.

La terapia celular como tratamiento de la insuficiencia cardíaca crónica

Directory of Open Access Journals (Sweden)

Ricardo Sanz

2008-01-01

Full Text Available Hasta hace poco tiempo se pensaba que el miocardio era un tejido sin capacidad de regeneración. El descubrimiento de progenitores celulares en el corazón de mamíferos adultos y la evidencia científica de que la reparación cardíaca existe han cambiado esta creencia, abriendo una nueva vía de investigación en el tratamiento de las enfermedades cardiovasculares. Durante años, circunscrita al ámbito de la investigación básica y de los ensayos preclínicos, esta nueva línea de investigación se ha trasladado al ámbito clínico, donde se están desarrollando ensayos en humanos para evaluar la seguridad, factibilidad y eficacia de dicha terapia celular en la regeneración miocárdica. En esta revisión nos centraremos en la terapia celular de la insuficiencia cardíaca crónica en humanos, recogiendo los antecedentes, tipos de células y vías de administración, así como los principales ensayos clínicos publicados hasta el momento.

Uudised : Fääri ooper Tallinnas. Sigur Ros Tallinnas

Index Scriptorium Estoniae

2008-01-01

10.-12. septembrini mängitakse Tallinnas Kultuurikatlas fääri helilooja Sunleif Rasmusseni ooperit "Hullu mehe aias", lavastajaks Robert Annus. 23. augustil annab Rock Cafés kontserdi Islandi eksperimentaalrocki ansambel Sigur Ros, kes esitleb oma viiendat albumit "Med sud i eyrum vid spilum endalaust" (mida võiks tõlkida "Mängime lõppematult, sumin kõrvus"

Abilinnapea Ratas pidas uputust paratamatuseks / Jüri Ratas ; interv. Piret Reiljan

Index Scriptorium Estoniae

Ratas, Jüri, 1978-

2004-01-01

Tallinna abilinnapea Jüri Ratas kommenteerib olukorda linnas, kus kahe päevaga sadas maha rohkem kui juulikuu sademete norm ette näeb. Vt. samas Meelis Eldermann. Miks veevärk vihmaga toime ei tulnud?

Eesti kirjandus suure ilma äärel / Jüri Talvet

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

1999-01-01

Eesti kirjanduse esindatusest teatmeteoses "Encyclopedia of world literature in the 20th century" (St. James Press, 1999) ja "Der Literatur Brockhaus" (München... [jt.] : B. I. Taschenbuchverlag, 1995). Ilmunud ka kogumikus: Talvet, Jüri. Ameerika märkmed, ehk, Kaemusi Eestist. Tartu : Ilmamaa, 2000, lk. 121-124

78 FR 55121 - Submission for Review: Self-Certification of Full-Time School Attendance for the School Year, RI...

Science.gov (United States)

2013-09-09

... Attendance for the School Year, RI 25-14 and Information; and Instructions for Completing the Self...-0032, Self-Certification of Full-Time School Attendance For The School Year, RI 25-14; and Information... technological collection techniques or other forms of information technology, e.g., permitting electronic...

Basophil FcεRI Expression in Chronic Spontaneous Urticaria: A Potential Immunological Predictor of Response to Omalizumab Therapy.

Science.gov (United States)

Deza, Gustavo; Bertolín-Colilla, Marta; Pujol, Ramon M; Curto-Barredo, Laia; Soto, Dulce; García, Maribel; Hernández, Pilar; Gimeno, Ramon; Giménez-Arnau, Ana M

2017-06-09

Although the efficacy of omalizumab has been clearly demonstrated in the treatment of chronic spontaneous urticaria (CSU), its mechanism of action, which results in improvement in CSU symptoms, is not entirely understood. This study investigated the effect of omalizumab on expression of the high-affinity IgE receptor (FcεRI) on blood basophils from patients with active CSU, and its association with the clinical response. Patients exhibiting significant clinical improvement showed a sharp reduction in the levels of basophil FcεRI after 4 weeks, which was maintained throughout the total duration of the treatment. Such evolution was not observed in non-responder patients. Furthermore, non-responders showed significantly lower baseline levels of FcεRI than responders. Baseline basophil FcεRI expression was found to be a potential immunological predictor of response to omalizumab (100% sensitivity and 73.2% specificity). The results of this study contribute to our knowledge of the therapeutic benefit and mechanism of action of anti-IgE therapy in CSU.

Tornide väljaku müüriäärse ala tulevik endiselt ebaselge / Askur Alas

Index Scriptorium Estoniae

Alas, Askur, 1973-

2004-01-01

Tallinna linna ja ehitusfirma Restor vaheline tüli linnamüüri äärse maa täisehitamise suhtes Suurtüki kvartalis pole lahendust leidnud. Linnaosavalitsus soovib müüri äärde parki ja tahab algatada ala detaiplaneeringut. Restoril on Plate ja Eppingi torni vahel ridaelamuboksid juba välja ehitatud

Functional characterization of the high affinity IgG Receptor : making heads and tails of FcγRI

NARCIS (Netherlands)

van der Poel, C.E.

2011-01-01

This thesis focuses on human FcγRI, a high affinity receptor for antibodies of the IgG isotype. IgG is the most abundant antibody type in blood and all currently FDA approved therapeutic antibodies are of the IgG isotype. FcγRI, a member of the activating Fcγ receptors, exists as a complex of a

Influência dos barorreceptores e da pressão arterial na resposta cardíaca à hipertensão renovascular em ratos

OpenAIRE

Kaleizu Teodoro Rosa

2008-01-01

No presente estudo, duas importantes situações foram abordadas no intuito de se melhor entender os mecanismos homeostáticos dos pressorreceptores na gênese da hipertrofia cardíaca em resposta à hipertensão renovascular: o efeito do tempo de clipe na artéria renal e o efeito dos níveis pressóricos e da variabilidade da pressão arterial. O curso temporal mostrou que, antes mesmo da instalação da hipertensão, há alteração da morfologia cardíaca, qual seja o desenvolvimento de uma hipertrofia ven...

Variabilidade da frequência cardíaca em neonatos prematuros e de termo

Directory of Open Access Journals (Sweden)

Fabio Augusto Selig

2011-06-01

Full Text Available FUNDAMENTO: Várias publicações têm demonstrado a importância do sistema nervoso autônomo por meio dos componentes simpático e parassimpático na gerência da interação entre as diferentes partes do organismo humano. Esses estudos aplicaram técnicas lineares e não lineares (Teoria do Caos de avaliação em diferentes situações, doenças e faixas etárias, tendo como ferramenta a variabilidade da frequência cardíaca (VFC. OBJETIVO: Aplicar os conhecimentos das dinâmicas linear e não linear na avaliação de neonatos prematuros (NPT, analisando sua VFC e comparando com neonatos de termo (NT saudáveis. MÉTODOS: Quarenta e oito neonatos prematuros com diferentes idades gestacionais tiveram seus batimentos cardíacos captados com auxílio do equipamento Polar Advanced S810i e sua VFC obtida pelo registro dos intervalos RR. A VFC foi analisada nos domínios do tempo (SDNN, RMSSD, SD1/SD2, da frequência (VLF, LF, HF e a relação LF/HF e do caos (TAU e sua normalização [TAU(n], Expoente de Lyapunov e Entropia. Os NPT foram comparados com um grupo de 78 NT saudáveis e sem intercorrências perinatais com auxílio do teste não paramétrico de Kruskal-Wallis. RESULTADOS: Detectou-se diferença estatisticamente significante entre os grupos para todas as variáveis estudadas, tanto no domínio do tempo como nos da frequência e do caos. CONCLUSÃO: Neonatos prematuros exibem comportamento menos complexo da variabilidade da frequência cardíaca que neonatos de termo, fato comprovado nos domínios do tempo, da frequência e do caos. O estudo da variabilidade cardíaca nesse grupo pode ser considerado uma ferramenta a mais na avaliação da maturação autonômica e, consequentemente, da progressão para eutrofia.

Efeitos do levosimendan sobre TNF-alfa, PNB e MMP-1 em pacientes com insuficiência cardíaca com anemia

Directory of Open Access Journals (Sweden)

Mutlu Büyüklü

2012-07-01

Full Text Available FUNDAMENTO: O levosimendan é conhecido pelo seu efeito bilateral de fortalecimento contração das miofibrilas sem aumentar a demanda de oxigênio no miocárdio. A anemia é uma deterioração que causa aumento da dosagem de fármacos em pacientes com insuficiência cardíaca. OBJETIVO: No presente estudo comparamos a eficácia do tratamento com levosimendan em pacientes com insuficiência cardíaca descompensada com ou sem anemia. MÉTODOS: Foram incluídos no estudo 23 pacientes anêmicos com insuficiência cardíaca classe 3 ou 4, segundo a New York Heart Association (NYHA e fração de ejeção abaixo de 35%. Outros 23 pacientes com o mesmo diagnóstico cardíaco, mas sem anemia, serviu como grupo controle. Ao tratamento da insuficiência cardíaca tradicional desses pacientes foi acrescido um tratamento de 24 horas de levosimendan. Amostras foram tomadas para dosar os níveis séricos do fator de necrose tumoral alfa sérico (TNF-alfa, peptídeo natriurético cerebral aminoterminal (NT-proPNB e metaloproteinase da matriz 1 (MMP-1, antes e após a administração. RESULTADOS: Não houve diferença significativa entre os níveis séricos de TNF-alfa e MMP-1, antes e depois do tratamento (p > 0,05. Embora o nível de NT-proBNP tenha diminuído em ambos os grupos após o tratamento, não foi estatisticamente significativo (p = 0,531 e p = 0,913 para os grupos de anemia e de controle, respectivamente. Uma restauração significativa da capacidade funcional foi observada em ambos os grupos avaliados, de acordo com a NYHA (p < 0,001 e p = 0,001 para os grupos de anemia e controle, respectivamente. CONCLUSÃO: O tratamento com levosimendan apresenta efeitos semelhantes em pacientes com insuficiência cardíaca, com anemia e sem anemia. No entanto, o efeito precoce desse tratamento sobre os níveis de TNF-alfa, NT-proPNB e MMP-1 não é evidente. Ele oferece uma melhora significativa na capacidade funcional, sem a influência da anemia.

Comportamento do ergorreflexo na insuficiência cardíaca

Directory of Open Access Journals (Sweden)

Juliana Fernanda Canhadas Belli

2011-08-01

Full Text Available Grande número de evidências tem sugerido a existência de uma rede de reflexos que se tornam hiperativos secundariamente a alterações músculo-esqueléticas que ocorrem na síndrome insuficiência cardíaca (IC. Estes, aliados aos reflexos cardiovasculares simpato-inibitórios, suprimidos na síndrome, podem contribuir para a intolerância ao exercício físico. A hiperativação dos sinais originados dos receptores localizados nos músculos esqueléticos (mecanoceptores - metaborreceptores é uma hipótese proposta recentemente para explicar a origem dos sintomas de fadiga e dispneia e os efeitos benéficos do treinamento físico na síndrome da IC. Na IC, outras alterações nos sistemas de controle reflexo, que não são mutuamente exclusivos, contribuem para dispneia. Estimulação inapropriada dos barorreceptores arteriais com consequente falta de inibição da descarga do metaborreflexo muscular e quimiorreflexo carotídeo e aumento da vasoconstricção renal com liberação de angiotensina II pode também ser considerada. Apesar das alterações funcionais dos reflexos terem sido usadas de maneira independente para ilustrar a excitação simpática observada na IC, a interação entre esses reflexos em condições normais e patológicas, especialmente sua contribuição para o estado simpato-excitatório encontrado na IC, não tem sido amplamente estudados. Assim, o problema se ambos os receptores musculares (mecano e metaborreceptores estão envolvidos na gênese da exacerbação do ergorreflexo observado na IC ainda fica a ser resolvido. Dessa forma, essa revisão tem por objetivo integrar os conhecimentos a respeito do mecano e metaborreflexo (ergorreflexo na síndrome da insuficiência cardíaca bem como esclarecer a influência da terapêutica medicamentosa da IC no ergorreflexo.

Comportamento da frequência cardíaca em imersão nas situações de repouso e durante exercícios de hidroginástica

Directory of Open Access Journals (Sweden)

Mabel Micheline Olkoski

Full Text Available INTRODUÇÃO: A frequência cardíaca é um parâmetro de fácil utilização para prescrição e controle da intensidade do exercício. Ao realizar um exercício no meio aquático ocorrem alterações fisiológicas significativas que devem ser compreendidas para a prescrição de exercícios, ocasionando assim os efeitos adaptativos adequados. OBJETIVO: Realizar uma revisão sistemática da literatura sobre o comportamento da frequência cardíaca em imersão nas situações de repouso e durante exercícios de hidroginástica e sobre os fatores que a influenciam. RESULTADOS: Os estudos envidenciam que a frequência cardíaca pode ser influenciada pela profundidade devido ao gradiente de pressão hidrostática exercido sobre o corpo, bem como à termorregulação diferenciada. Em repouso, a frequência cardíaca pode variar de acordo com as diferentes temperaturas da água, posições corporais e profundidades. No entanto, a magnitude do efeito de cada um desses fatores sobre a frequência cardíaca ainda não é bem definido. CONCLUSÃO: Durante a realização de exercícios de hidroginástica, essa variável é proporcional à velocidade de execução do exercício, à utilização de equipamento resistivo, à área projetada e ao grupo muscular envolvido e inversamente proporcional à profundidade.

Verbascumkurdistanicum (Scrophulariaceae), a new species from Hakkâri, Turkey.

Science.gov (United States)

Fırat, Mehmet

2015-01-01

Verbascumkurdistanicum Fırat (Scrophulariaceae), is described and illustrated as a new species that is located in Hakkâri, Turkey. In this study, diagnostic morphological characters of this and closely related species (Verbascumoreophilum K.Koch and Verbascumpyramidatum M. Bieb) are discussed. Furthermore, distribution maps for the three taxa are provided.

Kas Orase Shelley või Shelley Oras? / Jüri Talvet

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

1999-01-01

Arvustus: Shelley, Percy Bysshe. Valik lüürikat / tlk. Ants Oras; toim. Anne Lange. Tln. : Hortus Litterarum, 1998. Ants Orase ja Minni Nurme tõlgete võrdlus (P. B. Shelley. Luuletusi. Tln., 1960). Ilmunud ka kogumikus: Talvet, Jüri. Tõrjumatu äär. Tartu : Ilmamaa, 2005, lk. 408-416

BIPM comparison BIPM.RI(II)-K1.Eu-152 of activity measurements of the radionuclide 152Eu for the VNIIM (Russia), the LNE-LNHB (France) and the CNEA (Argentina), with linked results for the COOMET.RI(II)-K2.Eu-152 comparison

International Nuclear Information System (INIS)

Michotte, C.; Ratel, G.; Courte, S.; Kharitonov, I.A.; Zanevsky, A.V.; Terechtchenko, E.E.; Moune, M.; Aubineau-Laniece, I.; Bobin, C.; Arenillas, P.; Balpardo, C.

2014-01-01

Three new participants in the BIPM.RI(II)-K1.Eu-152 comparison have been added to the previous results and this has produced a revised value for the key comparison reference value (KCRV), calculated using the power-moderated weighted mean. A link has been made to the COOMET.RI(II)-K2.Eu-152 comparison held in 2010 through the VNIIM who participated in both comparisons. Three National Metrology Institutes (NMIs) used the K1 or K2 comparisons to update their degree of equivalence. The degrees of equivalence between each equivalent activity measured in the International Reference System (SIR) and the KCRV have been calculated and the results are given in the form of a table for four NMIs in the BIPM.RI(II)-K1.Eu-152 comparison, three participants in the COOMET.RI(II)-K2.Eu-152 comparison and the 18 other participants in the previous CCRI(II)-K2.Eu-152 comparison. A graphical presentation is also given. (authors)

78 FR 52580 - Submission for Review: Request for Case Review for Enhanced Disability Annuity Benefit, RI 20-123

Science.gov (United States)

2013-08-23

... Disability Annuity Benefit, RI 20-123 AGENCY: U.S. Office of Personnel Management. ACTION: 60-Day notice and... Disability Annuity Benefit, RI 20-123. As required by the Paperwork Reduction Act of 1995, (Pub. L. 104-13... review the computations of disability annuities to include the formulae provided in law for individuals...

Fibrilação atrial no pós-operatório de cirurgia cardíaca: quem deve receber quimioprofilaxia?

Directory of Open Access Journals (Sweden)

Glaucylara Reis Geovanini

2009-04-01

Full Text Available Avaliar fatores de risco arritmogênicos associados à maior incidência de fibrilação atrial (FA no pós-operatório (PO de cirurgia cardíaca (revascularização miocárdica e/ou cirurgia valvar, com o intuito de selecionar os mais propensos ao desenvolvimento dessa arritmia para possível quimioprofilaxia. Avaliarem-se 66 pacientes submetidos à cirurgia cardíaca eletiva. Correlacionaram-se os principais fatores de risco (idade avançada, doença valvar (DV, aumento atrial esquerdo (AE, disfunção ventricular (DVE, distúrbio eletrolítico (DHE, cirurgia cardíaca prévia (CCP, uso prévio e suspensão de betabloqueador (B-Bloq e/ou digital 24 horas antes da cirurgia para o desenvolvimento de FA no PO. A incidência de FA foi elevada (47% em nossa casuística e mais freqüente no primeiro dia de PO. Dos pacientes pesquisados, 64% eram do sexo masculino com idade média de 62 anos. Entre os pacientes com dois ou menos fatores de risco para FA, apenas 24% desenvolveram a arritmia, enquanto a presença de três ou mais desses fatores esteve associada à sua maior incidência no PO (69%, (p = 0,04. Em ordem de maior freqüência, idade > 65 anos (em 58% dos pacientes foi o fator de risco mais prevalente, seguido de aumento do AE em 45% (p = 0,001 e DV em 38% (p = 0,02. A presença de três ou mais fatores de risco aumenta consideravelmente a incidência dessa arritmia no PO de cirurgia cardíaca. Entre os principais fatores, destacaram-se idade avançada, aumento do AE e doença valvar.

Itaalias vangistati peaprokuröri tappa tahtnud mafioosod / Ülle Toode

Index Scriptorium Estoniae

Toode, Ülle, 1969-

2005-01-01

Sitsiilias vahistati ligi poolsada maffiaorganisatsiooni Cosa Nostra väidetavat liiget. Politseini oli jõudnud info, et mafioosod kavatsevad lähiajal tappa Palermo peaprokuröri Pietro Grasso, tabamata on Cosa Nostra juht. Lisa: Kohtunik üksi sõjas maffia vastu

ABORDĂRI ŞTIINŢIFICE PRIVIND DEFINIŢIA CONTABILITĂŢII DE GESTIUNE

Directory of Open Access Journals (Sweden)

Maia BAJAN

2016-12-01

Full Text Available Contabilitatea de gestiune a evoluat de la o contabilitate a costurilor, în care accentul se punea pe determinarea costului de producţie, până la un domeniu distinct al contabilităţii, unde aceasta este orientată spre analiză şi previziune, accentul fiind axat pe gestiune. Analiza opiniilor savanţilor, expuse în literatura de specialitate autohtonă şi străină, permite identificarea a trei tipuri de abordări ştiinţifice ale definiţiei contabilităţii de gestiune, şi anume: conservative, moderate şi radicale. Contabilitatea de gestiune expusă prin abordări conservative are ca sarcină de bază colectarea şi analiza costurilor de producţie; prin abordări moderate este considerată drept sistem de transmitere a informaţiei necesare pentru luarea deciziilor manageriale; prin abordări radicale fiind recunoscută printr-un sistem de gestionare a entităţii în general şi pe subdiviziuni separate.SCIENTIFIC APPROACHES TO THE DEFINITION OF MANAGEMENT ACCOUNTINGManagement accounting has evolved from cost accounting that put emphasis on the determination of the production cost, to a distinct accounting domain, directed towards analysis and prevision, with a strong focus on management. The analysis of researchers’ opinions, presented in local and foreign literature, allows the identification of three types of scientific approaches to the definition of management accounting, namely: conservative, moderate and radical. The conservative approach on managerial accounting has the basic task of collecting and analyzing productions costs; the moderate approach is considered as a system of transmitting the required information for the management decision-making process, and the radical approach can be recognized in an entity’s general management system, as well as in its separate subdivisions.

Enfermedad cardíaca grave en la esclerosis sistémica Severe cardiac disease in scleroderma

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Alejandro R. Grinberg

2004-10-01

Full Text Available Una mujer de 36 años de edad con diagnóstico de esclerosis sistémica (ES desarrolló un cuadro agudo de miositis esquelética e insuficiencia cardíaca grave. Evolucionó con shock cardiogénico y a pesar del tratamiento con drogas inotrópicas y altas dosis de corticoides falleció a los cinco días de haber ingresado. La autopsia reveló áreas de necrosis coagulativa miocárdicas con miocitolisis y necrosis en banda de contracción. Son muy pocos los casos comunicados de insuficiencia cardíaca grave asociada a la ES.A 36 year-old female with a diagnosis of systemic sclerosis suffered from an acute episode of skeletal myositis and refractory heart failure with cardiogenic shock. Despite immunosuppressive treatment with high doses of corticosteroids and hemodynamic support she died five days after admission. The autopsy showed cardiac myocytolysis, myocyte necrosis and contraction band necrosis. There are very few reported cases of severe heart failure associated to systemic sclerosis.

Fase de convalecencia en la rehabilitación cardíaca. Protocolo de actuación

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Susana Hernández García

2015-03-01

Full Text Available La fase de convalecencia de la rehabilitación cardíaca tiene como propósito fundamental mejorar la capacidad funcional y fomentar un cambio del estilo de vida a través de todos los aspectos que integra la prevención secundaria fundamentalmente, en la incorporación a un programa de entrenamiento físico y en el control de los factores de riesgo cardiovascular, lo que favorece la reincorporación social y laboral de los enfermos. Con el objetivo de actualizar el protocolo de actuación de esta fase en nuestra institución se establecieron diferentes ejercicios con sus dosificaciones y recomendaciones para la rehabilitación de diferentes poblaciones, así como controles de la sesión de entrenamiento físico a tener en cuenta. Este protocolo permitirá aunar estrategias para mejorar la intervención fisioterapéutica en la fase de convalecencia del Programa Nacional de Rehabilitación Cardíaca en Cuba.

Accurate placement of substrate RNA by Gar1 in H/ACA RNA-guided pseudouridylation.

Science.gov (United States)

Wang, Peng; Yang, Lijiang; Gao, Yi Qin; Zhao, Xin Sheng

2015-09-03

H/ACA RNA-guided ribonucleoprotein particle (RNP), the most complicated RNA pseudouridylase so far known, uses H/ACA guide RNA for substrate capture and four proteins (Cbf5, Nop10, L7Ae and Gar1) for pseudouridylation. Although it was shown that Gar1 not only facilitates the product release, but also enhances the catalytic activity, the chemical role that Gar1 plays in this complicated machinery is largely unknown. Kinetics measurement on Pyrococcus furiosus RNPs at different temperatures making use of fluorescence anisotropy showed that Gar1 reduces the catalytic barrier through affecting the activation entropy instead of enthalpy. Site-directed mutagenesis combined with molecular dynamics simulations demonstrated that V149 in the thumb loop of Cbf5 is critical in placing the target uridine to the right position toward catalytic D85 of Cbf5. The enzyme elegantly aligns the position of uridine in the catalytic site with the help of Gar1. In addition, conversion of uridine to pseudouridine results in a rigid syn configuration of the target nucleotide in the active site and causes Gar1 to pull out the thumb. Both factors guarantee the efficient release of the product. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

Taquiarritmias postoperatorias en la cirugía cardíaca del adulto. Profilaxis

OpenAIRE

Fernando Enríquez; Antonio Jiménez

2010-01-01

Las arritmias en el periodo postoperatorio de la cirugía cardíaca suelen ser un hallazgo común ligado a múltiples mecanismos. Las condiciones particulares inherentes al acto quirúrgico pueden iniciar, facilitar o agravar un evento arrítmico por modificaciones en el sustrato anatómico y en sus moduladores. Aunque tradicionalmente consideradas como arritmias transitorias, diversos estudios muestran su asociación con una mayor morbimortalidad, riesgo de ictus, compromiso hemodinámico, iatrogenia...

Basophil FcεRI Expression in Chronic Spontaneous Urticaria: A Potential Immunological Predictor of Response to Omalizumab Therapy

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Gustavo Deza

2017-03-01

Full Text Available Although the efficacy of omalizumab has been clearly demonstrated in the treatment of chronic spontaneous urticaria (CSU, its mechanism of action, which results in improvement in CSU symptoms, is not entirely understood. This study investigated the effect of omalizumab on expression of the high-affinity IgE receptor (FcεRI on blood basophils from patients with active CSU, and its association with the clinical response. Patients exhibiting significant clinical improvement showed a sharp reduction in the levels of basophil FcεRI after 4 weeks, which was maintained throughout the total duration of the treatment. Such evolution was not observed in non-responder patients. Furthermore, non-responders showed significantly lower baseline levels of FcεRI than responders. Baseline basophil FcεRI expression was found to be a potential immunological predictor of response to omalizumab (100% sensitivity and 73.2% specificity. The results of this study contribute to our knowledge of the therapeutic benefit and mechanism of action of anti-IgE therapy in CSU.

ABORDĂRI ŞTIINŢIFICE PRIVIND DEFINIŢIA CONTROLULUI DE GESTIUNE

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Maia BAJAN

2016-12-01

Full Text Available Controlul de gestiune a evoluat de la o activitate de control, unde se punea accent pe verificarea şi realizarea unei norme prestabilite, până la un instrument de gestionare a entităţii, care reflectă un spectru larg de probleme legate de procesul de realizare a obiectivelor. Analiza temeinică a literaturii de specialitate, autohtone şi străine, privind definiţia controlului de gestiune permite a delimita opiniile savanţilor în două grupe de abordări ştiinţifice, şi anume: clasice şi moderne. Controlul de gestiune redat prin abordări clasice se consideră drept o tehnică de calcul care asigură măsurarea performanţelor, iar prin abordări moderne se prezintă ca un instrument strategic de gestionare a entităţii pe viitor.SCIENTIFIC APPROACHES IN DEFINING MANAGEMENT CONTROLManagement control has evolved from a control activity, where the main target was to verify and realize the default standard, to an entity management tool, that reflects a wide range of problems related to the process of objectives achievement. A deep analysis of the domestic and foreign specialty literature concerning the definition of management control, allows the division of scientists’ views into two groups of scientific approaches, and mainly: classical and modern. The classical approach of management control is considered a computing which ensures the measurement of performances, while the modern approach represents a strategic tool for further entity management.

DETERMINATION OF ATTENUATION INDEX CURVE "Ri(f" FOR HOMOGENEOUS DOUBLE LOCKING ELEMENTS

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BUZATU G. C.

2016-12-01

Full Text Available The paper is structured in three parts. In the first part of the paper, are presented some theoretical notions regarding the sound, noise, the sound insulations materials. Also in the first part of the paper are presented some characteristic regarding the insulation materials and there effects. In the second part it is described an calculation example for a homogeneous wall with double structure in order to determine the attenuation index curve "Ri(f". The example calculation contains 10 steps that must be followed and the final results are presented in table 7 and figure 3. The last part of the paper is represented by conclusions, where the authors tried to explain the importance of the curve "Ri(f" for reducing the noise in the buildings.

Suporte ventilatório na capacidade funcional de pacientes com insuficiência cardíaca: estudo piloto

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Eugênia da Silva Lima

2011-03-01

Full Text Available FUNDAMENTO: A insuficiência cardíaca é um importante problema de saúde pública, apresentando a dispneia e a fadiga como principais sintomas clínicos. A utilização do suporte ventilatório não invasivo vem atuando como coadjuvante da reabilitação cardíaca na tentativa de melhorar a capacidade funcional dos pacientes. OBJETIVO: Avaliar a capacidade funcional de pacientes com insuficiência cardíaca submetidos ao suporte ventilatório. MÉTODOS: Foram avaliados dados sociodemográficos, qualidade de vida, FC, pressão arterial (PA, saturação periférica de oxigênio (SpO2, dispneia, concentração de lactato, antes e depois do teste de caminhada de 6 minutos, e a distância percorrida de pacientes com insuficiência cardíaca crônica (ICC, de ambos os sexos, com fração FEVE < 45,0%, randomizados em dois grupos: controle e CPAP (utilizou CPAP 10 cmH2O por 30 minutos. RESULTADOS: Participaram 12 pacientes com ICC classe funcional II e III (NYHA, com média de fração de ejeção do ventrículo esquerdo (FEVE, % de 35,3 ± 8,7, sendo que 8 eram do sexo masculino. A média de idade foi de 46,3 ± 10,3 anos. Na comparação entre os grupos Controle e CPAP, no final do 6º min, foi encontrada diferença significativa nos valores de SpO2% entre os grupos (Controle: 93,6 ± 1,5 % vs CPAP: 96,1 ± 1,8%; p = 0,027, dispneia (Controle: 13,1 ± 1,16 vs CPAP: 11 ± 0,8; p = 0,009, concentração de lactato (Controle: 3,3 ± 0,7 mmol/l vs CPAP: 2,3 ± 0,5 mmol/l; p = 0,025, e distância percorrida no TC6 (Controle: 420,6 ± 73,8 m vs CPAP: 534 ± 89,91 m; p = 0,038. CONCLUSÃO: A realização prévia do CPAP apresentou efeitos benéficos na SpO2, na dispneia, na concentração de lactato, no duplo produto e na distância percorrida no TC6 de pacientes com ICC na realização do TC6.

Nõukogu kinnitas Türi kolledži õppetöö kolimise Tartusse

Index Scriptorium Estoniae

2010-01-01

Novembrikuu istungil otsustas TÜ nõukogu Türi kolledžis oleva keskkonnakorralduse ja planeerimise õppekava liita Tartus loodus- ja tehnoloogiateaduskonna (LOTE) juurde. TÜ peahoone ees protestisid selle kava vastu kolledži üliõpilased

Aneurisma de artéria ilíaca interna roto: relato de caso Ruptured internal iliac artery aneurysm: case report

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Cristina Toledo Afonso

2009-03-01

Full Text Available Aneurismas isolados da artéria ilíaca interna são raros, acometem 0,1% da população e correspondem a 1% dos aneurismas aorto-ilíacos. Na maioria das vezes, os pacientes são assintomáticos, mas podem apresentar dor abdominal, massa pulsátil no hipogástrio ou na fossa ilíaca, sintomas compressivos urinários, gastrointestinais ou neurológicos. Podem ocasionar quadro de abdome agudo, principalmente quando há ruptura. O diagnóstico precoce dos aneurismas isolados de artéria ilíaca interna é incomum, sendo identificados quando mais volumosos ou rotos, o que aumenta significativamente sua morbimortalidade e torna seu prognóstico mais reservado. Dessa forma, representam um desafio terapêutico. A ligadura cirúrgica tem sido o tratamento mais comum, entretanto a cirurgia endovascular tem mostrado bons resultados, inclusive nos aneurismas rotos. É relatado caso de aneurisma de artéria ilíaca interna isolado roto diagnosticado durante laparotomia para abordagem de abdome agudo.Isolated internal iliac artery aneurysms are rare. They affect 0.1% of the population, and account for 1% of aortoiliac aneurysms. Patients are mostly asymptomatic, yet they can have abdominal pain, pulsatile mass in the hypogastrium or iliac fossa, or urinary, gastrointestinal or neurological compressive symptoms. Such aneurysms are likely to course with an acute abdomen, especially when ruptured. Early diagnosis of isolated internal iliac artery aneurysms is difficult, as they are more easily detected when larger or ruptured, which significantly raises their morbidity and mortality rate and determines a poor prognosis. Therefore, they are a therapeutic challenge. Surgical ligation has been the most common treatment; however, the endovascular approach has presented good outcomes, even in the event of ruptured aneurysms. A case of ruptured isolated iliac artery aneurysm diagnosed during a laparotomy (acute abdomen approach is reported.

Preoperative tumor localization of primary hyperparathyroidism. Comprehensive study of ultrasonography (US), scintigraphy (RI), arteriography (AG) and venous sampling (VS)

Energy Technology Data Exchange (ETDEWEB)

Morita, Yutaka; Shinohara, Masahiro; Ito, Kazuo; Imamura, Fumimoto; Kasai, Yoichi (Hokkaido Univ., Sapporo (Japan). School of Medicine); Ishizuka, Reiki

1983-02-01

The diagnostic rate of each methods were discussed in thirty six cases and the following conclusions were made. (1.) The diagnostic rate of US, RI, AG and VS was 64.7%, 50%, 57.9%, 60.7% respectively. (2.) Ultrasonography and subtruction-scintigraphy were useful for screening examination for localization of parathyroid tumor. (3.) The reasonable diagnostic procedures were as follows: (1) In the cases of palpable, reno-uretrolithiasic type, and biochemical type: US ..-->.. RI ..-->.. VS. (2) In the cases of nonpalpable osteolytic type, and previous neck surgery: US ..-->.. RI ..-->.. AG ..-->.. VS. These results indicate that the systemic diagnoses are useful to predict localization of parathyroid tumors.

Taquiarritmias postoperatorias en la cirugía cardíaca pediátrica

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Fernando Enríquez

2010-10-01

Full Text Available Las arritmias postoperatorias son frecuentes en la cirugía de las cardiopatías congénitas. Esta revisión actualiza y expone la evidencia científica sobre la incidencia, fisiopatología, profilaxis y tratamiento de las taquiarritmias en la cirugía cardíaca pediátrica. Existe muy poca información basada en estudios aleatorizados en pediatría, siendo la mayoría de las publicaciones series de diversos centros quirúrgicos.

Valitsus tahab kaotada üüri piirmäärad / Anne Oja

Index Scriptorium Estoniae

Oja, Anne, 1970-

2004-01-01

Valitsus kiitis heaks eelnõu üüri piirmäärade kaotamise kohta. Tallinna linnavalitsus on piirmäärade kaotamise vastu, kuna see halvendaks abilinnapea Aivar Pärna sõnul oluliselt sundüürnike olukorda

Tagakiusamine ja kirjutamiskunst / Leo Strauss ; järelsõna Jüri Lipping

Index Scriptorium Estoniae

Strauss, Leo, 1899-1973

2000-01-01

Ajalooliste tekstide ridade vahele peidetud sõnumi lugemisest. Tsensuuri mõjust filosoofilistele tekstidele. Peidetud sõnumi lugemisest lähtuvast erinevusest eelmoodsate ja uusaegsete filosoofide teostes. Jüri Lipping'u järelsõna Leo Straussi filosoofilistest vaadetest.

Kuidas käib kultuuri suurandmete äri maailmas? / Indrek Ibrus

Index Scriptorium Estoniae

Ibrus, Indrek

2016-01-01

Septembri lõpus Eestis toimuvast konverentsist "Culture 4D: Digitisation, Data, Disruptions, Diversity", mille korraldavad Euroopa Nõukogu, kultuuriministeerium ja Tallinna Ülikool. Konverentsi tähelepanu keskmes on kultuurivaldkonna suurandmete majandamine, suurandmete äri, andmete kasutamine üldiseks hüvanguks ning kultuuri digiteerimisega kaasnevad väljakutsed

Jukose kriis toob äikesepilved vaguniäri kohale / Toivo Tänavsuu

Index Scriptorium Estoniae

Tänavsuu, Toivo

2004-01-01

Russian Estonian Rail Services AS - kõige konkurentsivõimelisem transpordi-, side- ja logistikaettevõtete hulgas, Hansapanga kõrgepalgalise eksportööri eriauhinna laureaat. Lisa: Russian Estonian Rail Services 2003. Kommenteerib Indrek Neivelt. Tabel: Transpordi-, side- ja logistikaettevõtted

Seguridad del paciente en el postoperatorio de cirugía cardíaca en UCI

OpenAIRE

Álvarez Menéndez, Katia

2013-01-01

Describir las medidas de seguridad del paciente que se adoptan en el postoperatorio de cirugía cardíaca en UCI y comprobar que dichas medidas de seguridad del paciente son efectivas y proporcionan beneficios a los pacientes. Para ello se describen todos los protocolos y dispositivos específicos y se comparan los resultados obtenidos en cuanto a los protocolos de Neumonía Zero y Bacteriemia Zero.

Eluruumi üürniku õiguste kaitse üüri ühepoolse suurendamise ja ebamõistliku suuruse korral : [bakalaureusetöö] / Martin Kalberg ; Tartu Ülikooli Õigusinstituut ; juhendaja: Kalev Saare

Index Scriptorium Estoniae

Kalberg, Martin

2006-01-01

Üüri suuruse ajalooline ülevaade ja võrdlus, üüri suurus eluruumi üürilepingu olulise osana, üüri ühepoolse suurendamise võimalused, üürniku vaidlustamisvõimalused üüri suurendamise korral

Effective research and innovation (R&I) policy in the EU-28: A causal and configurational analysis of political governance determinants

NARCIS (Netherlands)

Turkeli, S.; Kemp, R.P.M.

2015-01-01

Effective research and innovation (R&I) policy depends on the extent to which ideas, interests and institutional mechanisms for policy making work together rather than work against each other. In a political governance model for effective R&I policy in the EU-28, the separate influence of

Tulevane linnapea kavandab kainestusmaja ja Kalevipoega / Jüri Ratas ; interv. Urmas Seaver

Index Scriptorium Estoniae

Ratas, Jüri, 1978-

2005-01-01

Ilmunud ka: Postimees : na russkom jazõke 14. nov., lk 6. Tõenäoline Tallinna linnapea kandidaat vastab küsimustele, mis puudutavad uue linnavalitsuse esimest istungit, pealinna 2006. aasta eelarvet ning Keskerakonna valimislubadusi linna valitsemisel. Lisa: Jüri Ratas

Incidência de cirurgia cardíaca em octogenários: estudo retrospectivo Incidencia de cirugía cardíaca en octogenarios: estudio retrospectivo Incidence of cardiac surgery in octogenarian patients: retrospective study

Directory of Open Access Journals (Sweden)

Luciano Brandão Machado

2003-09-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: O aumento da expectativa de vida faz com que pacientes cada vez mais idosos tenham indicação de tratamento cirúrgico de cardiopatias. Este estudo tem como objetivo avaliar a incidência de pacientes com mais de 80 anos submetidos à cirurgia cardíaca no Instituto do Coração do Hospital das Clínicas da FMUSP, nos últimos 16 anos. MÉTODO: Foram analisados, no período de 1986 a 2001, o número de cirurgias de revascularização do miocárdio (RM e cirurgia valvar (CV e, em cada grupo, o número de cirurgias em pacientes com mais de 80 anos. Os dados foram analisados descritivamente. RESULTADOS: Os dados revelam aumento progressivo do número de octogenários submetidos à cirurgia cardíaca. As cirurgias de revascularização do miocárdio tiveram aumento de 0,13% em 1986 para 3,5% em 2001. As cirurgias valvares aumentaram de 0% em 1986 para 1,44% em 2001, registrando o maior valor de 3,02% em 1999. CONCLUSÕES: Os conhecimentos da fisiopatologia, da senilidade e os avanços no manuseio do trauma cirúrgico estão permitindo estender os recursos da cirurgia cardíaca no grupo de paciente mais idoso. A escolhas da técnica anestésica deve ser criteriosa, bem como a hidratação, a assistência ventilatória e a analgesia pós-operatória, permitindo redução da morbimortalidade neste grupo de maior risco cirúrgico.JUSTIFICATIVA Y OBJETIVOS: El aumento de la expectativa de vida hace con que pacientes cada vez mas edosos tengan indicación de tratamiento quirúrgico de cardiopatias. Este estudio tiene como objetivo evaluar la incidencia de pacientes con más de 80 años sometidos a cirugía cardíaca en el Instituto del Corazón del Hospital de Clínicas de la FMUSP, en los últimos 16 años. MÉTODO: Fueron analizados, en el período de 1986 a 2001, el número de cirugías de revascularización del miocardio (RM y cirugía valvar (CV y, en cada grupo, el número de cirugías en pacientes con más de 80 a

XX sajandi hispaania teater : peamärgid / Jüri Talvet

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

1998-01-01

Hispaania ja ladinaameerika näitekirjandusest. Ka näidendite lavastamisest eesti teatrites. Põhjalikumalt Ram̤n MarÍa del Valle-Incl{u00E1ni (1866-1936), Federico GarcÍa Lorca (1898-1936) ja Antonio Buero Vallejo (sünd. 1916) loomingust. Ilmunud ka kogumikus: Talvet, Jüri. Tõrjumatu äär. Tartu : Ilmamaa, 2005, lk. 234-250

MODULAÇÃO AUTONÔMICA DA FREQUÊNCIA CARDÍACA E CAPACIDADE FUNCIONAL AERÓBICA EM HEMIPARÉTICOS

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Mônica Furquim de Campos

Full Text Available RESUMO Introdução: Tem sido observado que indivíduos acometidos por acidente vascular encefálico (AVE apresentam, além dos danos físicos, diminuição da capacidade aeróbica e alteração da modulação autonômica da frequência cardíaca, sendo estes importantes fatores para o aparecimento de doenças cardíacas e arritmias. Objetivo: Investigar os efeitos crônicos do AVE sobre a capacidade aeróbica (VO2pico e os índices de variabilidade da frequência cardíaca (VFC, e se existe correlação entre essas duas variáveis. Métodos: Foram avaliados 11 indivíduos do sexo masculino, com idade entre 55 e 65 anos, acometidos por lesão cerebrovascular há pelo menos seis meses, e todos com hemiparesia. Foram realizadas as seguintes avaliações: teste de capacidade aeróbica máxima; registro dos intervalos R-R e cálculo dos índices da VFC (RMSSD, pNN50, AF, BF e a razão BF/AF. Para comparação entre VO2pico previsto e obtido utilizou-se o teste t de Student não pareado. Para testar a hipótese de correlação entre os índices de VFC e o VO2pico utilizou-se o teste de correlação de Pearson. Resultados: VO2pico (mL.kg-1.min-1 previsto e obtido, respectivamente = 32,15 ± 1,87 e 16,12 ± 5,51; índices da VFC: RMSSD (ms = 28,69 ± 26,78; pNN50 (% = 8,76 ± 12,62; AF (u.n. = 51,96 ± 22,4; BF (u.n. = 48,04 ± 22,49. O VO2pico correlacionou-se negativamente com os índices RMSSD, pNN50 e AF e positivamente com o índice BF (p < 0,05. Conclusão: Na fase crônica do AVE, variabilidade da frequência cardíaca encontra-se normal e os indivíduos com menor capacidade aeróbica apresentam maior modulação parassimpática e menor simpática, provavelmente em consequência da maior exigência física nas atividades de vida diária.

The molecular gradient using the divide-expand-consolidate resolution of the identity second-order Møller-Plesset perturbation theory: The DEC-RI-MP2 gradient

Energy Technology Data Exchange (ETDEWEB)

Bykov, Dmytro; Kristensen, Kasper; Kjærgaard, Thomas [Department of Chemistry, qLeap Center for Theoretical Chemistry, University of Aarhus, DK-8000 Århus C (Denmark)

2016-07-14

We report an implementation of the molecular gradient using the divide-expand-consolidate resolution of the identity second-order Møller-Plesset perturbation theory (DEC-RI-MP2). The new DEC-RI-MP2 gradient method combines the precision control as well as the linear-scaling and massively parallel features of the DEC scheme with efficient evaluations of the gradient contributions using the RI approximation. We further demonstrate that the DEC-RI-MP2 gradient method is capable of calculating molecular gradients for very large molecular systems. A test set of supramolecular complexes containing up to 158 atoms and 1960 contracted basis functions has been employed to demonstrate the general applicability of the DEC-RI-MP2 method and to analyze the errors of the DEC approximation. Moreover, the test set contains molecules of complicated electronic structures and is thus deliberately chosen to stress test the DEC-RI-MP2 gradient implementation. Additionally, as a showcase example the full molecular gradient for insulin (787 atoms and 7604 contracted basis functions) has been evaluated.

The molecular gradient using the divide-expand-consolidate resolution of the identity second-order Møller-Plesset perturbation theory: The DEC-RI-MP2 gradient

International Nuclear Information System (INIS)

Bykov, Dmytro; Kristensen, Kasper; Kjærgaard, Thomas

2016-01-01

We report an implementation of the molecular gradient using the divide-expand-consolidate resolution of the identity second-order Møller-Plesset perturbation theory (DEC-RI-MP2). The new DEC-RI-MP2 gradient method combines the precision control as well as the linear-scaling and massively parallel features of the DEC scheme with efficient evaluations of the gradient contributions using the RI approximation. We further demonstrate that the DEC-RI-MP2 gradient method is capable of calculating molecular gradients for very large molecular systems. A test set of supramolecular complexes containing up to 158 atoms and 1960 contracted basis functions has been employed to demonstrate the general applicability of the DEC-RI-MP2 method and to analyze the errors of the DEC approximation. Moreover, the test set contains molecules of complicated electronic structures and is thus deliberately chosen to stress test the DEC-RI-MP2 gradient implementation. Additionally, as a showcase example the full molecular gradient for insulin (787 atoms and 7604 contracted basis functions) has been evaluated.

RiSA: A Science Festival for the Bilingual and Bicultural Rio Grande Valley

Science.gov (United States)

Key, Joey Shapiro; Torres, Cristina; Stone, Robert

2014-03-01

The Rio Grande Science and Arts (RiSA) Festival organized by the Center for Gravitational Wave Astronomy (CGWA) at the University of Texas at Brownsville (UTB) will use a wide variety of artforms to bring physics and science topics to the bilingual and bicultural population of the Rio Grande Valley of South Texas. The science and art faculty at UTB will partner with art and education professionals to create an annual community event celebrating science though art. Music, dance, poetry, and visual arts will headline the festival activities. Festival events and products will be produced in both English and Spanish to attract and inform the bilingual local community. The RiSA Festival is supported by the Science Festival Alliance and the Sloan Foundation. Supported by the Science Festival Alliance and the Sloan Foundation.

The experiences to improve plant performance and reliability of Ko-Ri nuclear power plants

International Nuclear Information System (INIS)

Kang, Ho Weon

1998-01-01

This paper provides a discussion of the lessons learned from operational experience and the future plans to improve performance of the Ko-Ri plant. To operate nuclear power plants safely with good performance is the only way to mitigate the negative image of nuclear power generation to the public and to enhance the economical benefit compared to other electrical generation method. Therefore, in a continuous effort to overcome a negative challenge from outside, we have driven an aggressive 'OCTF' campaign as part of safety. As a result of our efforts, the following remarkable achievements have been accomplished. (1) 3 times of OCTF during recent three years (2) Selected twice as a top notch power plant on the list of NEI magazine in terms of plant capacity factor (3) No scram recorded in 1997 for all 4 units at Ko-Ri site. Ko-Ri is now undergoing the large scale plant betterment projects for retaking-off our operating performance to the level of new challenge target. Such improvement of critical components in the reactor coolant system and turbine system greatly contribute to increase the safety and reliability of the plant and to shortening of the planned outage period as well as to reduction of radiation exposure and radwaste. (Cho, G. S.). 5 tabs., 10 figs

Layout Design of Human-Machine Interaction Interface of Cabin Based on Cognitive Ergonomics and GA-ACA

OpenAIRE

Deng, Li; Wang, Guohua; Yu, Suihuai

2016-01-01

In order to consider the psychological cognitive characteristics affecting operating comfort and realize the automatic layout design, cognitive ergonomics and GA-ACA (genetic algorithm and ant colony algorithm) were introduced into the layout design of human-machine interaction interface. First, from the perspective of cognitive psychology, according to the information processing process, the cognitive model of human-machine interaction interface was established. Then, the human cognitive cha...

Consideraciones nutricionales en el paciente con falla cardíaca crónica Nutritional considerations in patients with chronic heart failure

Directory of Open Access Journals (Sweden)

Mario A Hernández

2012-12-01

Full Text Available La insuficiencia cardíaca congestiva es un síndrome caracterizado por reducción del gasto cardíaco, aumento de las presiones de llenado ventricular y activación neuroendocrina, que lleva a un proceso de fibrosis y apoptosis de la célula cardíaca. Afecta alrededor de 23 millones de personas en el mundo y confiere un pésimo pronóstico una vez se diagnostica. Desde el punto de vista fisiopatológico, la relación entre citocinas pro-inflamatorias, activación neuro-hormonal y alteraciones gastrointestinales conduce a un estado denominado caquexia cardíaca, determinado por pérdida acelerada de peso, fatiga, reducción de la fuerza muscular, anorexia y disminución de la calidad de vida; este proceso es capaz de deteriorar aún más el pronóstico vital de estos pacientes. En las últimas dos décadas, se han realizado avances en el tratamiento farmacológico y eléctrico de la falla cardíaca; sin embargo los estudios en el campo no farmacológico son pocos, en especial en el aspecto nutricional, y así mismo son escasas las recomendaciones de las guías internacionales acerca del tema. En estudios pequeños, una aproximación nutricional ha demostrado impactar de manera positiva la calidad de vida y tolerancia al ejercicio, si bien se requieren grandes estudios para determinar la viabilidad de este abordaje en pacientes con falla cardíaca.Congestive heart failure is a syndrome characterized by reduced cardiac output, increased ventricular filling pressures and neuroendocrine activation, which leads to a process of cardiac cell fibrosis and apoptosis. It affects nearly 23 million people worldwide and once diagnosed has a poor prognosis. From a physiopathological point of view, the relationship between pro-inflammatory cytokines, neurohormonal activation and gastrointestinal disturbances leads to a condition called cardiac cachexia, characterized by accelerated weight loss, fatigue, decreased muscle strength, anorexia and decreased

Avaliação por ressonância magnética de massas cardíacas

Directory of Open Access Journals (Sweden)

Maria Fernanda Braggion-Santos

2013-09-01

Full Text Available FUNDAMENTO: Tumores cardíacos são extremamente raros; no entanto, quando há suspeita clínica, é necessária a correta avaliação diagnóstica, para planejar o tratamento mais adequado. Nesse contexto, a ressonância magnética cardiovascular tem um papel importante, permitindo uma abrangente caracterização de tais lesões. OBJETIVO: Revisar os casos encaminhados a um Serviço de Ressonância Magnética para investigação de massas cardíacas e paracardíacas. Descrever a série de casos positivos, juntamente de uma breve revisão da literatura para cada tipo de lesão e sobre o papel da ressonância magnética cardiovascular em sua avaliação. MÉTODOS: Entre agosto de 2008 e dezembro de 2011, foram revistos todos os casos de pacientes encaminhados a ressonância magnética com suspeita de neoplasia envolvendo o coração. Foram selecionados aqueles com confirmação histopatológica, evolução ou resposta terapêutica compatíveis com a suspeita clínica e achados de imagem. RESULTADOS: Entre os 13 pacientes incluídos neste estudo, oito (62% tiveram confirmação histopatológica. Foram descritas cinco neoplasias benignas (mixomas, rabdomioma e fibromas, cinco neoplasias malignas (sarcoma, linfoma, síndrome de Richter cardíaca e doença metastática e três lesões não neoplásicas (cisto pericárdico, trombo intracardíaco e vegetação infecciosa. CONCLUSÃO: A informação disponível sobre essa questão é escassa. Estudos prospectivos adicionais são necessários para elucidar o papel desses nutrientes no risco cardiovascular de pacientes com diabetes.

Puugravüüriklotsid kõnelevad / Jüri Hain

Index Scriptorium Estoniae

Hain, Jüri, 1941-

2007-01-01

Näitus "Sajand eesti puugravüüri klotsidel Eesti Rahvusraamatukogu kollektsioonist" rahvusraamatukogus 15. I - 3. II. Näitusel on vanim klots aastast 1842, noorim 1941. aastast. Kunstnikest (Aleksander Otto Gern, Bogdan Gottlieb Friedrich Kally, August Daugell, Eduard Magnus Jakobson, Mart Pukits, Andres Kuusk, Anton Suurkask, Arkadio Laigo, Hando Mugasto, Eduard Järv, Paul Liivak, Salome Trei, Ott Kangilaski), töödest. Näitust täiendavad Eduard Wiiralti "Tüdruku pea" (1919) kaks linoollõikeplaati

Uudised : Tüüri Viiulikontsert Taanis. Lepo Sumera filmimuusika CD. Eesti muusikaauhinnad 2000

Index Scriptorium Estoniae

2001-01-01

E.-S. Tüüri Viiulikontserdi Taani esiettekandest Kopenhaagenis. 2. märtsil esitleti Kinomajas L. Sumera filmimuusika plaati. 3. märtsil andis Eesti Fonogrammitootjate Ühing klubis Decolte üle 2000. a. eesti muusikaauhinnad

Jüri Arrak nüüdis- ja vanamuusikas / Igor Garšnek

Index Scriptorium Estoniae

Garšnek, Igor, 1958-

2011-01-01

8. novembril Niguliste kirikus toimunud Hortus Musicuse Jüri Arraku 75. sünnipäevale pühendatud kontserdist, kus tulid esiettekandele Rene Eespere, Tõnis Kaumanni ja Peeter Vähi kunstnikule pühendatud uudisteosed

Äriühinguõiguse ühtlustamine Euroopa Liidus ja selle mõju Eesti õigusele : [magistritöö] / Greete-Kristiine Kuru ; Tartu Ülikool, õigusteaduskond ; juhendaja: Andres Vutt

Index Scriptorium Estoniae

Kuru, Greete-Kristiine, 1989-

2013-01-01

Äriühinguõiguse ühtlustamise alustest ja läbiviimisest Euroopa Liidus, äriühingute piiriülesest asukohavahetusest Euroopa Liidus, äriühingute piiriülese ühinemise regulatsioonist Euroopa Liidus

76 FR 15246 - Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI

Science.gov (United States)

2011-03-21

...-AA01 Anchorage Regulations; Narragansett Bay and Rhode Island Sound, RI AGENCY: Coast Guard, DHS... Rhode Island Sound south of Brenton Point, Rhode Island, for use by vessels waiting to enter... Sound that under current informal practice is routinely used by mariners as an anchorage while waiting...

Polimorfismo G894T da óxido nítrico-sintetase endotelial e o prognóstico na insuficiência cardíaca

Directory of Open Access Journals (Sweden)

Oziel Marcio Araujo Tardin

2013-10-01

Full Text Available FUNDAMENTO: Estudos prévios avaliaram o papel do polimorfismo genético da enzima óxido nítrico-sintetase endotelial sobre o prognóstico na insuficiência cardíaca. Entretanto, faltam estudos relacionando o G894T e a insuficiência cardíaca na população brasileira. OBJETIVO: Avaliar a associação do G894T com o prognóstico de amostra de pacientes brasileiros com insuficiência cardíaca. MÉTODOS: Coorte com 145 pacientes com insuficiência cardíaca sistólica, num segmento de 40 meses (média = 22 meses, em dois hospitais universitários do Estado do Rio de Janeiro. Foi avaliada a relação do G894T com os desfechos: remodelamento reverso; melhora da classe funcional (NYHA; taxas de mortalidade e hospitalização. Os diâmetros do átrio e ventrículo esquerdos e a fração de ejeção do ventrículo esquerdo foram medidos na admissão e após 6 meses, para avaliação do remodelamento reverso. A melhora na classe funcional foi avaliada após 6 meses e as taxas de mortalidade e de hospitalização durante todo o seguimento. A raça foi autodeclarada. O polimorfismo G894T foi analisado por reação em cadeia de polimerase e por análise do polimorfismo dos fragmentos de restrição. RESULTADOS: A frequência genotípica foi GG (40%, GT (48,3% e TT (11,7%, e a frequência alélica foi guanina (64,1% e tiamina (35,8%. Não houve diferença entre as frequências genotípica ou alélica conforme a raça autodeclarada, tampouco conforme as características basais. Não houve relação entre o genótipo ou a frequência alélica e os desfechos analisados. CONCLUSÃO: Não se observou associação do polimorfismo G894T (Glu298Asp com o prognóstico de amostra de pacientes ambulatoriais brasileiros com insuficiência cardíaca sistólica.

Verbascum kurdistanicum (Scrophulariaceae, a new species from Hakkâri, Turkey

Directory of Open Access Journals (Sweden)

Mehmet Fırat

2015-07-01

Full Text Available Verbascum kurdistanicum Fırat (Scrophulariaceae, is described and illustrated as a new species that is located in Hakkâri, Turkey. In this study, diagnostic morphological characters of this and closely related species (V. oreophilum K.Koch and V. pyramidatum M. Bieb are discussed. Furthermore, distribution maps for the three taxa are provided.

Jüri Uluots jõudis võõrsilt koju / Rein Hanson

Index Scriptorium Estoniae

Hanson, Rein, 1948-

2008-01-01

Endise Eesti peaministri ja peaministri presidendi ametis Jüri Uluotsa ja tema abikaasa ning poja säilmed maeti 31. augustil 2008 Kirbla kalmistule. Ümbermatmise tseremoonial esines kõnega ka president Toomas Hendrik Ilves. Vt. samas foto: Koguduse juhatuse esimees vallavanem Anu-Lii Jürman tervitab Kirbla kiriku trepil Eesti Vabariigi presidenti Toomas Hendrik Ilvest

La enfermedad celíaca se podría detectar con una determinación de anticuerpos antitransglutaminasa en la saliva

OpenAIRE

Cuestas Montañés, Eduardo José; Ortega Páez, Eduardo

2011-01-01

Este estudio avanza en la posibilidad de realizar una prueba de cribado simple e inocua para detectar la enfermedad celíaca a edades tempranas, lo que puede contribuir a disminuir la morbimortalidad asociada a la enfermedad.

The Birth Satisfaction Scale-Revised Indicator (BSS-RI).

Science.gov (United States)

Martin, Colin R; Hollins Martin, Caroline; Redshaw, Maggie

2017-08-29

The current study sought to develop a short birth satisfaction indicator utilising items from the Birth Satisfaction Scale-Revised (BSS-R) for use as a brief measure of birth satisfaction and as a possible key performance indicator for perinatal service delivery evaluation. Building on the recently developed BSS-R, the study aimed to develop a simplified version of the instrument to assess birth satisfaction easily that could work as a short evaluative measure of clinical service delivery for labour and birth that is consistent with policy documents, placing women at the centre of the birth experience. The six item Birth Satisfaction Scale-Revised Indicator (BSS-RI) was embedded within the 2014 National Maternity Survey for England. A random selection of mothers who had given birth in a two week period in England were surveyed three months after the birth. Using a two-stage design and split-half dataset, exploratory factor analysis, confirmatory factor analysis, internal consistency, convergent, divergent and known-groups discriminant validity evaluation were conducted in a secondary analysis of the survey data. Using this large population based survey of recent mothers the short revised measure was found to comprise two distinct domains of birth satisfaction, 'stress and emotional response to labour and birth' and 'quality of care'. The psychometric qualities of the tool were robust as were the indices of validity and reliability evaluated. The BSS-RI represents a short easily administered and scored measure of women's satisfaction with care and the experience of labour and birth. The instrument is potentially useful for researchers, service evaluation and policy makers.

Modeling tools for an Integrated River-Delta-Sea system investigation: the Pan-European Research Infrastructure DANUBIUS-RI philosophy

Science.gov (United States)

Umgiesser, Georg; Bellafiore, Debora; De Pascalis, Francesca; Icke, Joost; Stanica, Adrian

2017-04-01

The DANUBIUS Research Infrastructure (DANUBIUS-RI) is a new initiative to address the challenges and opportunities of research on large river- sea (RS) systems. DANUBIUS-RI is a distributed pan-European RI that will provide a platform for interdisciplinary research. It will deal with RS investigation through facilities and expertise from a large number of European institutions becoming a 'one-stop shop' for knowledge exchange in managing RS systems, ranging from freshwater to marine research. Globally, RS systems are complex and dynamic, with huge environmental, social and economic value. They are poorly understood but under increasing pressure through pollution, hydraulic engineering, water supply, energy, flood control and erosion. RS systems in Europe are among the most impacted globally, after centuries of industrialisation, urbanisation and agricultural intensification. Improved understanding is essential to avoid irreversible degradation and for restoration. DANUBIUS-RI will provide, among a number of other facilities concerning observations, analyses, impacts' evaluation, a modeling node that will provide integrated up-to-date tools, at locations of high scientific importance and opportunity, covering the RS systems - from source (upper parts of rivers - mountain lakes) to the transition with coastal seas. Modeling will be one of the major services provided by DANUBIUS-RI, relying on the inputs from the whole RI. RS systems are challenging from a modelling point of view, because of the complex morphology and the wide temporal and spatial range of processes occurring. Scale interaction plays a central role, considering the different hydro-eco-morphological processes on the large (basin) and small (local, coast, rivers, lagoons) scale. Currently, different model applications are made for the different geographical domains, and also for subsets of the processes. For instance there are separate models for rainfall runoff in the catchment, a sewer model for the

Political Ideology and Its Relationship to Perceptions of Social Justice Advocacy among Members of the American Counseling Association (ACA)

Science.gov (United States)

Steele, Janee Marie

2010-01-01

Social justice has become an increasingly controversial topic among members of the American Counseling Association (ACA). Specifically, concerns have been raised over what is perceived to be: (a) the liberal political agenda of social justice advocates, (b) the marginalization of conservative counselors, and (c) the inappropriate use of ACA…

Sotsiaalteaduskond 1993-2007 / Kristel Marmor ; meenutavad Aleksander Pulver, Jüri Kruusvall ja Arno Baltin

Index Scriptorium Estoniae

Marmor, Kristel

2008-01-01

11. jaanuaril 2008. aastal tähistas sotsiaalteaduskond oma 15. tegevusaastat ja samas ka matust. Meenutused psühholoogiaprofessor Aleksander Pulverilt, sotsioloogia vanemteadurilt Jüri Kruusvallilt ning matusekõne Arno Baltinilt

Nuclear structure physics at RI beam factory

International Nuclear Information System (INIS)

Otsuka, Takaharu

1998-01-01

The nuclear structure physics is becoming extremely interesting owing to recent development of RI beam factories. Among various interesting developments in this field, I will focus upon two subjects. One is the breaking of the usual magic numbers in unstable nuclei, and the other is the invention of a new method for quantum many-body problems: Quantum Monte Carlo diagonalization method (QMCD). For the first subject, I will discuss the vanishing of N=8 and 20 magic numbers in 11 Li and 32 Mg, respectively. For the latter, I will present brief description of the theory and results of some applications including the one to 64 Ge, a proton-rich unstable nucleus. (author)

Anna Lampérière, solidarité et citoyenneté féminine sous la Troisième République

Directory of Open Access Journals (Sweden)

Anne R. Epstein

2008-12-01

Full Text Available Cet article examine les idées de l’institutrice Anna Lampérière, l’une des rares femmes à avoir contribué à la discussion théorique sur l’idéologie de la solidarité pendant la Troisième République. Vue dans le contexte de son parcours personnel et de son engagement civique, la pensée d’A. Lampérière offre un aperçu inédit d’un modèle solidariste de citoyenneté féminine sans droit de vote. Au sein d’une culture d’associations florissante au début du XXe siècle, elle participe à la création et au fonctionnement d’importantes associations mixtes qui, par l’éducation civique, visent la mise en place de l’idéologie solidariste de Léon Bourgeois. Se proclamant anti-féministe, Anna Lampérière se présente néanmoins comme une défenseuse de la cause des femmes et du progrès social et, comme beaucoup de ses contemporains, elle place la réforme scolaire au cœur de son projet républicain. Après une analyse de la vision sociale d’Anna Lampérière, l’article examine les pratiques civiques et la structure mixte selon les sexes de la Société pour l’éducation sociale, une association pour la promotion du solidarisme, dont elle a été Secrétaire générale. L’idéologie solidariste et sa pratique avaient un attrait pour des femmes républicaines comme Anna Lampérière qui avaient une vocation civique mais qui n’étaient pas attirées par un modèle égalitaire de la citoyenneté.Anna Lampérière, solidarité and female citizenship in the Third Republic This article explores the ideas of educator Anna Lampérière, one of the rare women to contribute significantly to the theoretical discussion about the ideology of solidarity during the Third Republic. Viewed in tandem with her own personal history and civic activism, Lampérière’s thought provides unique insight into a possible solidarist model of female citizenship without voting rights. Operating within the flourishing associational

Dolores Hoffmann pani Türi kiriku aknad särama / Marge Laagemann

Index Scriptorium Estoniae

Laagemann, Marge

2005-01-01

vitraažikunstnik räägib Türi kiriku vitraažidest, oma teekonnast vitraažide juurde, vitraažide valmistamisest, nende tekkest, ajaloost ning mõjust. Järgneb 2005. 9. dets., lk. 9, 16. dets., lk. 7, 23. dets., lk. 11 ja 30. dets., lk. 7

10 aastat - 30 ettevõtet : KPMG kogemus tasakaalus tulemuskaardiga / Jüri Sakkeus

Index Scriptorium Estoniae

Sakkeus, Jüri

2008-01-01

Tasakaalus tulemuskaardi koostamise ja rakendamise nõuded, selle plussid ja miinused ning mõju ettevõtte arengule. Vt. samas: Tarmo Noop. Loon süsteemi, mis töötab ise; Kaido Kangur. Kas teate, millal teie äri kokku kukub?; Marko Rillo. Tasakaalus tulemuskaardi sobivusest ja mittesobivusest. Skeemid

Reduced Fc∊RI-Mediated Release of Asthma-Promoting Cytokines and Chemokines from Human Basophils during Omalizumab Therapy

Science.gov (United States)

Oliver, Janet M.; Tarleton, Christy A.; Gilmartin, Laura; Archibeque, Tereassa; Qualls, Clifford R.; Diehl, Lorena; Wilson, Bridget S.; Schuyler, Mark

2010-01-01

Background Treating asthmatics with the humanized IgE-scavenging antibody, omalizumab (rhuMAb-E25, Xolair®), reduces airways inflammation and asthma symptoms. Previously, omalizumab was shown to cause a dramatic and reversible loss of cell surface high-affinity IgE receptors, Fc∊RI, from the peripheral blood basophils of asthmatics. The consequences of receptor loss for the Fc∊RI-mediated synthesis and release of cytokines implicated in allergic asthma have not been examined. Methods Fifteen asthmatic volunteers each received omalizumab for 12 weeks. Peripheral blood basophils were isolated before, during, 2 weeks after and 6 months after omalizumab. Basophils were assayed for the basal and anti-IgE-stimulated release of cytokines, chemokines and histamine. Pooled data were analyzed by repeated measures ANOVA and by paired t tests. Results Anti-IgE-stimulated human basophils synthesize and release Th2 cytokines (IL-4, IL-13) and chemokines (IL-8, RANTES). The anti-IgE-stimulated release of IL-4, IL-13 and IL-8 was reduced during omalizumab treatment and returned to pretreatment levels after omalizumab withdrawal. Omalizumab did not alter basophil histamine levels or basal and anti-IgE-stimulated histamine release. Conclusions Omalizumab may reduce asthma symptoms in part by suppressing the Fc∊RI-mediated production by basophils of Th2 cytokines and selected chemokines. Anti-IgE-stimulated basophil cytokine synthesis appears more sensitive than histamine release to the loss of Fc∊RI caused by omalizumab treatment. PMID:19844128

GarcÍa Lorca luulest ja Ain Kaalepi tõlkest / Jüri Talvet

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

1998-01-01

Arvustus: GarcÍa Lorca, Federico. Mu kätes põleb tuli : valitud luuletused / tlk. ja saateks: Ain Kaalep. 2. tr. Tallinn : Vagabund, 1997. Ilmunud ka kogumikus: Talvet, Jüri. Tõrjumatu äär. Tartu : Ilmamaa, 2005, lk. 442-453

When public health and genetic privacy collide: positive and normative theories explaining how ACA's expansion of corporate wellness programs conflicts with GINA's privacy rules.

Science.gov (United States)

Bard, Jennifer S

2011-01-01

The Patient Protection and Affordable Care Act of 2010 (ACA) contains many provisions intended to increase access to and lower the cost of health care by adopting public health measures. One of these promotes the use of at-work wellness programs by both providing employers with grants to develop these programs and also increasing their ability to tie the price employees pay for health insurance for participating in these programs and meeting specific health goals. Yet despite ACA's specific alteration of three different statues which had in the past shielded employees from having to contribute to the cost of their health insurance based on their achieving employer-designated health markers, it chose to leave alone recently enacted rules implementing the Genetic Non-Discrimination Act (GINA), which prohibits employers from asking employees about their family health history in any context, including assessing their risk for setting wellness targets. This article reviews how both the changes made by ACA and the restrictions recently put place by GINA will affect the way employers are likely to structure Wellness Programs. It also considers how these changes reflect the competing social goals of both ACA, which seeks to expand access to the population by lowering costs, and GINA, which seeks to protect individuals from discrimination. It does so by analyzing both positive theories about how these new laws will function and normative theories explaining the likelihood of future friction between the interests of the population of the United States as a whole who are in need of increased and affordable access to health care, and of the individuals living in this country who risk discrimination, as science and medicine continue to make advances in linking genetic make-up to risk of future illness. © 2011 American Society of Law, Medicine & Ethics, Inc.

The experiences to improve plant performance and reliability of Ko-Ri nuclear power plants

Energy Technology Data Exchange (ETDEWEB)

Kang, Ho Weon [Korea Electric Power Corp. Ko-Ri nuclear power division, Ko-Ri (Korea, Republic of)

1998-07-01

This paper provides a discussion of the lessons learned from operational experience and the future plans to improve performance of the Ko-Ri plant. To operate nuclear power plants safely with good performance is the only way to mitigate the negative image of nuclear power generation to the public and to enhance the economical benefit compared to other electrical generation method. Therefore, in a continuous effort to overcome a negative challenge from outside, we have driven an aggressive 'OCTF' campaign as part of safety. As a result of our efforts, the following remarkable achievements have been accomplished. (1) 3 times of OCTF during recent three years (2) Selected twice as a top notch power plant on the list of NEI magazine in terms of plant capacity factor (3) No scram recorded in 1997 for all 4 units at Ko-Ri site. Ko-Ri is now undergoing the large scale plant betterment projects for retaking-off our operating performance to the level of new challenge target. Such improvement of critical components in the reactor coolant system and turbine system greatly contribute to increase the safety and reliability of the plant and to shortening of the planned outage period as well as to reduction of radiation exposure and radwaste. (Cho, G. S.). 5 tabs., 10 figs.

Enzymatic activity and immunoreactivity of Aca s 4, an alpha-amylase allergen from the storage mite Acarus siro

Czech Academy of Sciences Publication Activity Database

Pytelková, Jana; Lepšík, Martin; Šanda, Miloslav; Talacko, Pavel; Marešová, Lucie; Mareš, Michael

2012-01-01

Roč. 13, č. 3 (2012), s. 1-8 ISSN 1471-2091 R&D Projects: GA ČR GP525/09/P600 Institutional research plan: CEZ:AV0Z40550506 Keywords : Aca s 4 * Acarus siro * alpha - amylase s Subject RIV: CE - Biochemistry Impact factor: 1.776, year: 2012 http://www.biomedcentral.com/1471-2091/13/3

Rae vald ja Jüri elanikud sõdivad tehnopargi ohtliku tehase vastu / Mari Kodres

Index Scriptorium Estoniae

Kodres, Mari

2008-01-01

Ettevõte Stainless Surface Technology OÜ soovib rajada Jüri tehnoparki metallide hapetega töötlemise tehase. Rae valla ehitusameti juhataja Enno Harmipaiga hinnangul on probleem tehase ja elumajade ühine kanalisatsioon

Prevalencia de malformaciones cardíacas congenitas en 44,985 nacimientos en Colombia§

OpenAIRE

Baltaxe,Erik; Zarante,Ignacio

2006-01-01

Objetivo: Estimar la prevalencia de malformaciones congenitas cardíacas en Colombia usando la metodología del Estudio Colaborativo Latinoamericano de Malformaciones Congenitas y hacer una descripción epidemiológica de la población estudiada. Material y métodos: Estudio prospectivo de casos y controles anidado en una cohorte que incluyó 44,985 neonatos nacidos entre junio 1 de 2001 y abril 30 de 2005 en once hospitales de Colombia. Resultados: Se reportaron 55 casos (1.2 por 1,000). Treinta y ...

A gas circulation and purification system for gas-cell-based low-energy RI-beam production

Energy Technology Data Exchange (ETDEWEB)

Sonoda, T.; Wada, M.; Katayama, I.; Kojima, T. M.; Reponen, M. [RIKEN Nishina Center for Accelerator-Based Science, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Tsubota, T. [Tokyo KOATSU Co., Ltd., 1-9-8 Shibuya, Shibuyaku, Tokyo 150-0002 (Japan)

2016-06-15

A gas circulation and purification system was developed at the RIKEN Radioactive Isotope Beam Factory that can be used for gas-cell-based low-energy RI-beam production. A high-flow-rate gas cell filled with one atmosphere of buffer gas (argon or helium) is used for the deceleration and thermalization of high-energy RI-beams. The exhausted buffer gas is efficiently collected using a compact dry pump and returned to the gas cell with a recovery efficiency of >97%. The buffer gas is efficiently purified using two gas purifiers as well as collision cleaning, which eliminates impurities in the gas. An impurity level of one part per billion is achieved with this method.

Jüri Sillart: Hea film on kui õhkõrn orhidee või maavillane parmupill : [2003. a. ilmunud artikli oluliselt täiendatud versioon] / Jüri Sillart ; intervjueerinud Margus Mikomägi

Index Scriptorium Estoniae

Sillart, Jüri, 1943-2011

2013-01-01

Filmirežissöör, -operaator ja Tallinna Ülikooli filmipedagoog eesti filmist ja enda omadest veidi lähemalt. 29. mail oleks Jüri Sillart saanud 70-aastaseks. Ka tema endiste õpilaste Elari Lendi ja Madis Reimundi meenutused

N-Heterocyclic Carbene Coinage Metal Complexes of the Germanium-Rich Metalloid Clusters [Ge9R3]− and [Ge9RI2]2− with R = Si(iPr3 and RI = Si(TMS3

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Felix S. Geitner

2017-07-01

Full Text Available We report on the synthesis of novel coinage metal NHC (N-heterocyclic carbene compounds of the germanium-rich metalloid clusters [Ge9R3]− and [Ge9RI2]2− with R = Si(iPr3 and RI = Si(TMS3. NHCDippCu{η3Ge9R3} with R = Si(iPr3 (1 represents a less bulky silyl group-substituted derivative of the known analogous compounds with R = Si(iBu3 or Si(TMS3. The coordination of the [NHCDippCu]+ moiety to the cluster unit occurs via one triangular face of the tri-capped trigonal prismatic [Ge9] cluster. Furthermore, a series of novel Zintl cluster coinage metal NHC compounds of the type (NHCM2{η3Ge9RI2} (RI = Si(TMS3 M = Cu, Ag and Au; NHC = NHCDipp or NHCMes is presented. These novel compounds represent a new class of neutral dinuclear Zintl cluster coinage metal NHC compounds, which are obtained either by the stepwise reaction of a suspension of K12Ge17 with Si(TMS3Cl and the coinage metal carbene complexes NHCMCl (M = Cu, Ag, Au, or via a homogenous reaction using the preformed bis-silylated cluster K2[Ge9(Si(TMS32] and the corresponding NHCMCl (M = Cu, Ag, Au complex. The molecular structures of NHCDippCu{η3Ge9(Si(iPr33} (1 and (NHCDippCu2{η3-Ge9(Si(TMS32} (2 were determined by single crystal X-ray diffraction methods. In 2, the coordination of the [NHCDippCu]+ moieties to the cluster unit takes place via both open triangular faces of the [Ge9] entity. Furthermore, all compounds were characterized by means of NMR spectroscopy (1H, 13C, 29Si and ESI-MS.

Caquexia associada à insuficiência cardíaca Heart failure-induced cachexia

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Marina Politi Okoshi

2013-05-01

Full Text Available Pacientes com insuficiência cardíaca frequentemente desenvolvem estado de caquexia, que constitui fator independente de redução da sobrevida. Caquexia pode ser diagnosticada quando ocorre perda de peso corporal maior que 6% do peso habitual, na ausência de outras doenças. Embora sua fisiopatologia não esteja completamente esclarecida, vários fatores parecem estar envolvidos, como diminuição da ingestão alimentar, anormalidades do trato gastrointestinal, ativação imunológica e neuro-hormonal e alteração da relação entre processos anabólicos e catabólicos. Como não há terapia específica para a caquexia associada à insuficiência cardíaca, o tratamento baseia-se no suporte nutricional, bloqueio neuro-hormonal, controle do edema e anemia e exercícios físicos. Fármacos com propriedades imunomodulatórias e anabólicas encontram-se em investigação clínica e experimental.Heart failure patients often develop cachexia, which is an independent factor for survival reduction. Cachexia can be diagnosed when there is loss of more than 6% of the body weight, in the absence of other diseases. Even though its pathophysiology has not yet been completely clarified, various factors seem to be involved, such as reduction in food consumption, gastrointestinal tract abnormalities, immunologic and neuro-hormonal activarion and changes in the relationship between anabolic and catabolic processes. Since there is not specific therapy for heart failure-induced cachexia, management is based on nutritional support, neuro-hormonal blockade, control of edema and anemia and exercise. Drugs with anabolic and immunomodulating properties are being evaluated and clinical and non-clinical trials.

Maamesilasena maailmas ehk lihtsalt Jüri Talveti meetodist / On Jüri Talvet’s Comparative Method

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Arne Merilai

2016-12-01

Full Text Available Teesid: Artikkel defineerib maailmakirjanduse professor Jüri Talveti komparativistlikku meetodit nii maamesilase metafoori kui ka tema poolt tutvustatud mõistete edaphos (’pind’ ja episteme (’teadmine’ kaudu. Võrdleva kirjandusteadlase ülesanne on kahesuunaline: tutvustada eesti kirjandust maailmas ja vahendada mujal loodut meie kultuurile. Kuigi õpetlaste teoreetiline metasüsteem ja mõistevõrk – episteme – võib areneda väga keeruliseks, peab see alati juurduma edaphos’es kui toitvas pinnases, mille loovad sõnakunstiteosed ja rahvuslikud kirjanduslood. Avardades võrdlevat edaphos’t, aktiveerime ja rikastame ka maailma episteme’t.   The article aims at defining the comparative method of Jüri Talvet, professor of comparative literature. This can be carried out by an application of Talvet’s own metaphor for himself – a bumble bee, or via two concepts elaborated by him – edaphos (base and episteme (knowledge. The bumble bee, by nature more reclusive and peaceful but somehow more attractive looks than a regular bee flies out from its modest sod nest across blooming meadows, disseminating homely pollen among the leaves of grass of the wide world. Then it faithfully returns with nourishing nectar that feeds its family. As chairman of the Estonian Comparative Literature Association, and founder and editor-in-chief of the comparative literature journal Interlitteraria, Talvet has written: “Its purpose is to channel new literary-philosophical ideas from the international area to Estonia and, at the same time, to spread knowledge about Estonian literary and philosophical studies outside Estonia, as well as to let the wider world have some idea of Estonian literature itself which, because of the language barrier, has belonged traditionally to the majority of “silent” literatures of the world, unjustly ignored by the area of the dominant Western languages.” Yet, no matter how complex our theoretical meta

Soome kriminullide tõlkimise võistluse võitis Jüri Valge

Index Scriptorium Estoniae

2003-01-01

Soome kriminaalkirjanduse tõlkevõistluse võitis Jüri Valge, teise koha pälvis Ave Leek, kolmandat kohta jagavad Anne Kütt, Annus Raud ja Meri-Liis Laherand. Tõlgitavateks autoriteks olid Leena Lehtolainen ja Reijo Mäki. Vt. ka Sirp, 2003, 14. nov., lk. 18; Eesti Päevaleht : Arkaadia, 14. nov., lk. 14. Vt. ka Looming, 2003, nr. 11, lk. 1750

Epidemiología de las taquiarritmias preoperatorias en la cirugía cardíaca

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Mario Castaño

2010-04-01

Full Text Available La prevalencia de las taquiarritmias es cada vez mayor con el envejecimiento de la población. Los avances en el conocimiento de los mecanismos fisiopatológicos de las arritmias han favorecido el interés creciente actual en su prevención, diagnóstico y tratamiento. En esta revisión abordamos los aspectos epidemiológicos de las taquiarritmias asociadas con la enfermedad cardíaca quirúrgica en pacientes pediátricos y adultos.

Proceeding of the workshop on gamma-ray spectroscopy utilizing heavy-ion, photon and RI beams

Energy Technology Data Exchange (ETDEWEB)

Oshima, Masumi; Sugita, Michiaki; Hayakawa, Takehito [eds.

1998-03-01

Three time since 1992, we have held the symposia entitled `Joint Spectroscopy Experiments Utilizing JAERI Tandem-Booster Accelerator` at the Tokai Research Establishment. In the symposia, we have mainly discussed the plans of experiments to be done in this joint program. The joint program started in 1994. Several experiments have been made since and some new results have already come up. This symposium `Gamma-ray Spectroscopy utilizing heavy-ion, Photon and RI beams` was held at Tokai Research Establishment of JAERI. Because this symposium is the first occasion after the program started, the first purpose of the symposium is to present and discuss the experimental results so far obtained using the JAERI Tandem-Booster. The second purpose of the symposium is to discuss new possibilities of gamma-ray spectroscopy using new resources such as RI-beam and Photon-beam. The participants from RIKEN, Tohoku University and JAERI Neutron Science Research Center presented the future plans of experiments with RI-beam at each facility. Compared with these nuclear beams, photon beam provides a completely new tool for the {gamma}-ray spectroscopy, which is achieved by inverse Compton scattering between high-energy electron and laser beams. The 23 of the presented papers are indexed individually. (J.P.N.)

21 ideed, millest võiks saada monument või skulptuur / Jüri Saar

Index Scriptorium Estoniae

Saar, Jüri, 1973-

2008-01-01

Tartu linnavalitsus kogus kokku 21 skulptuuride, monumentide ja mälestustahvlite ideed, et esile tõsta auväärseid kaaslinlasi ning ehitisi. Valmis dokument "Tartu linna monumentide ja skulptuuride rajamise kava aastateks 2008-2013". Kommenteerivad Tiit Kaunissaare ja Jüri Sasi

Efeitos do tartarato de metoprolol em pacientes portadores de insuficiência cardíaca Effects of metoprolol tartrate therapy in patients with heart failure

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José Albuquerque de Figueiredo Neto

2006-09-01

Full Text Available OBJETIVO: Estudar os efeitos do tartarato de metoprolol em pacientes portadores de insuficiência cardíaca. MÉTODOS: Foram avaliados em estudo prospectivo, 50 pacientes (36 homens com insuficiência cardíaca, classe funcional II a IV, com 52±14,8 anos, e fração de ejeção do ventrículo esquerdo (FEVE 0,05. A freqüência cardíaca apresentou redução de 78,84±batimentos por minuto para 67,48±1,86 batimentos por minuto (pOBJECTIVE: To study the effects of metoprolol tartrate therapy in patients with heart failure. METHODS: Fifty patients (36 males aged 52±14.8 yrs, with functional class II to IV heart failure (HF and left ventricular ejection fraction (LVFE 0.05. Cardiac frequency decreased from 78.84±1.68 to 67.48±1.86 b.p.m. (p<0.001. CONCLUSION: The adding of metoprolol tartrate to the usual heart failure therapy is followed by an increase of ejection fraction, functional class improvement, and decrease of ventricular diameters and cardiac frequency. These results suggest anti-remodeling effects in patients with HF who utilize metoprolol tartrate in addition to the usual therapy.

3D Scrape-off layer modelling with BoRiS

International Nuclear Information System (INIS)

Riemann, J.; Borchardt, M.; Schneider, R.; Mutzke, A.

2005-01-01

The 3D fluid transport code BoRiS is applied to a hydrogen plasma and a neutral fluid in a stellarator-like geometry equipped with a poloidal ring limiter. The results demonstrate the capability of dealing with 3D effects which can be related to both the influence of the geometry and the plasma-neutral interaction as well. The setup used has similarities with a poloidal gas target in a fusion device

Comparing chemical and biological control strategies for twospotted spider mites (Acari: Tetranychidae) in commercial greenhouse production of bedding plants.

Science.gov (United States)

Opit, George P; Perret, Jamis; Holt, Kiffnie; Nechols, James R; Margolies, David C; Williams, Kimberly A

2009-02-01

Efficacy, costs, and impact on crop salability of various biological and chemical control strategies for Tetranychus urticae Koch (Acari: Tetranychidae) were evaluated on mixed plantings of impatiens, Impatiens wallerana Hook.f (Ericales: Balsaminaceae), and ivy geranium, Pelargonium peltatum (1.) L'Hér. Ex Aiton (Geraniales: Geraniaceae), cultivars in commercial greenhouses. Chemical control consisting of the miticide bifenazate (Floramite) was compared with two biological control strategies using the predatory mite Phytoseiulus persimilis Athias-Henriot (Acari: Phytoseiidae). Treatments were 1) a single, early application of bifenazate; 2) a single, early release of predatory mites at a 1:4 predator:pest ratio based on leaf samples to estimate pest density; 3) a weekly release of predatory mites at numbers based on the area covered by the crop; and 4) an untreated control. T. urticae populations were monitored for 3 wk after the earliest treatment. When plants were ready for market, their salability was estimated. Bifenazate and density-based P. persimilis treatments effectively reduced T. urticae numbers starting 1 wk after plants had been treated, whereas the scheduled, area-based P. persimilis treatment had little or no effect. The percentage of flats that could be sold at the highest market wholesale price ranged from 15 to 33%, 44 to 86%, 84 to 95%, and 92 to 100%, in the control, weekly area-based P. persimilis, bifenazate, and single density-based P. persimilis treatments, respectively. We have shown that in commercial greenhouse production of herbaceous ornamental bedding plants, estimating pest density to determine the appropriate number of predators to release is as effective and offers nearly the same economic benefit as prophylactic use of pesticides.

Structural insights into the interaction of human IgG1 with FcγRI: no direct role of glycans in binding

Energy Technology Data Exchange (ETDEWEB)

Oganesyan, Vaheh, E-mail: oganesyanv@medimmune.com; Mazor, Yariv; Yang, Chunning; Cook, Kimberly E.; Woods, Robert M. [MedImmune LLC, 1 MedImmune Way, Gaithersburg, MD 20878 (United States); Ferguson, Andrew [AstraZeneca Pharmaceuticals, 35 Gatehouse Drive, Mailstop E3, Waltham, MA 02451 (United States); Bowen, Michael A.; Martin, Tom; Zhu, Jie; Wu, Herren; Dall’Acqua, William F., E-mail: oganesyanv@medimmune.com [MedImmune LLC, 1 MedImmune Way, Gaithersburg, MD 20878 (United States)

2015-10-31

In an effort to identify the critical structural features responsible for the high-affinity interaction of IgG1 Fc with FcγRI, the structure of the corresponding complex was solved at a resolution of 2.4 Å. The three-dimensional structure of a human IgG1 Fc fragment bound to wild-type human FcγRI is reported. The structure of the corresponding complex was solved at a resolution of 2.4 Å using molecular replacement; this is the highest resolution achieved for an unmutated FcγRI molecule. This study highlights the critical structural and functional role played by the second extracellular subdomain of FcγRI. It also explains the long-known major energetic contribution of the Fc ‘LLGG’ motif at positions 234–237, and particularly of Leu235, via a ‘lock-and-key’ mechanism. Finally, a previously held belief is corrected and a differing view is offered on the recently proposed direct role of Fc carbohydrates in the corresponding interaction. Structural evidence is provided that such glycan-related effects are strictly indirect.

Tratamento nutricional em pacientes com insuficiência cardíaca Nutritional treatment for heart failure patients

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Viviane Sahade

2009-06-01

Full Text Available A insuficiência cardíaca é um problema grave e crescente de saúde pública em todo o mundo, sendo a via final comum da maioria das cardiopatias. Apesar dos recentes avanços da medicina, pouca atenção vem sendo dada ao tratamento não farmacológico, em particular à terapia nutricional. A evolução clínica dos pacientes com insuficiência cardíaca, via de regra, caminha para quadros variáveis de desnutrição, de causa multifatorial e que não está necessariamente relacionada ao índice de massa corporal. Assim, o objetivo deste trabalho foi revisar a literatura na busca por evidências sobre a composição adequada da dieta no tratamento de pacientes com insuficiência cardíaca. Realizou-se uma revisão sistemática nas bases de dados Medline, Pubmed, Lilacs, SciELO e dos comitês nacionais e internacionais de saúde, dos artigos publicados no período compreendido entre 1981 e 2006. Observou-se que existem poucos estudos bem elaborados, sobre a adequação da dietoterapia na insuficiência cardíaca e que esta ainda é muito restrita ao controle do sal e de líquido, sendo dada pouca atenção à quantidade e à qualidade dos demais nutrientes. Existe uma crescente evidência de que a dieta é um fator importante no prognóstico e no tratamento desses pacientes, porém futuros estudos, incluindo ensaios clínicos com adequado número de participantes, se fazem necessários para que se possa prescrever, com segurança, suplementos nutricionais.Heart failure is a serious and increasing public health problem around the world, and is the common endpoint of most heart diseases. Despite recent medical advances, little attention has been given to the non-pharmacological treatments, specifically, to nutritional therapy. The clinical course of patients with heart failure constantly progresses to varying degrees of malnutrition caused by different factors and not necessarily related to body mass index. Thus, the objective of this study was

Fisher: a program for the detection of H/ACA snoRNAs using MFE secondary structure prediction and comparative genomics - assessment and update.

Science.gov (United States)

Freyhult, Eva; Edvardsson, Sverker; Tamas, Ivica; Moulton, Vincent; Poole, Anthony M

2008-07-21

The H/ACA family of small nucleolar RNAs (snoRNAs) plays a central role in guiding the pseudouridylation of ribosomal RNA (rRNA). In an effort to systematically identify the complete set of rRNA-modifying H/ACA snoRNAs from the genome sequence of the budding yeast, Saccharomyces cerevisiae, we developed a program - Fisher - and previously presented several candidate snoRNAs based on our analysis 1. In this report, we provide a brief update of this work, which was aborted after the publication of experimentally-identified snoRNAs 2 identical to candidates we had identified bioinformatically using Fisher. Our motivation for revisiting this work is to report on the status of the candidate snoRNAs described in 1, and secondly, to report that a modified version of Fisher together with the available multiple yeast genome sequences was able to correctly identify several H/ACA snoRNAs for modification sites not identified by the snoGPS program 3. While we are no longer developing Fisher, we briefly consider the merits of the Fisher algorithm relative to snoGPS, which may be of use for workers considering pursuing a similar search strategy for the identification of small RNAs. The modified source code for Fisher is made available as supplementary material. Our results confirm the validity of using minimum free energy (MFE) secondary structure prediction to guide comparative genomic screening for RNA families with few sequence constraints.

Unelõiv ja Saarepiiga: Jüri Talveti kirjanduslik "Kalevipoeg" / The Rhisomes of „Kalevipoeg“: Literary Interpretation of the Estonian National Epic by Jüri Talvet

Directory of Open Access Journals (Sweden)

Marin Laak

2016-12-01

Full Text Available Teesid: Artikkel keskendub eepose „Kalevipoeg“ käsitlusele võrdleva kirjandusteaduse vaatepunktist. „Kalevipoja“ uurimine ilukirjandusliku teosena muutis paradigmaatiliselt rahvuseepose senist tõlgendust ja seda tänu Jüri Talveti käsitlustele „Kalevipojast“ kui suurest Euroopa eeposest, silmapaistavast maailmakirjanduse kunsteeposte seas. Eepose teksti ja poeetika kirjandusteaduslik uurimine on selgitanud, kuidas eepose tekst on üles ehitatud sisemistele, intratekstuaalsetele seostele, mis korduvad gradatsiooniliselt ja toetuvad teatud kindlatele tekstuaalsetele sõlmpunktidele, näiteks „Saarepiiga“, „uni“ jpt. Enam kui autentsed allikad, on „Kalevipoja“ kui kirjandusliku teksti puhul oluline eepose toimimine pidevalt uusi tekste ärgitava tüvitekstina. Eepose analüüs näitab, kuidas selliste seoste alusel tekivad uued kultuurilised ühikud, kauneid näiteid selliste motiivikordustele rajatud seosteahelate kohta leidub ka Jüri Talveti luules.   The article focuses on the treatment of the epic The Kalevipoeg from the viewpoint of comparative literature. This approach is a continuation of the study of literary relations of the epic which, on the one hand is opposite to, but on the other hand continues the present folkloristic approach to The Kalevipoeg as a folklore-based epic, which is based on the comparative-historical method of studying folklore. F. R. Kreutzwald’s role in creating the national epic was enormous; the epic can be conceived as a fictional and intentional piece, emphasising the role of its author. Although different genres of genuine folklore can be recognised in the epic, works of fiction of European and world classics have also been used in its construction, and the text of the epic has itself become an intertextual foundation for new works of fiction. The paradigm of discussing the epic changed due to Jüri Talvet’s groundbreaking treatment of The Kalevipoeg as a great European epic and

Mutant RBL mast cells defective in Fc epsilon RI signaling and lipid raft biosynthesis are reconstituted by activated Rho-family GTPases.

Science.gov (United States)

Field, K A; Apgar, J R; Hong-Geller, E; Siraganian, R P; Baird, B; Holowka, D

2000-10-01

Characterization of defects in a variant subline of RBL mast cells has revealed a biochemical event proximal to IgE receptor (Fc epsilon RI)-stimulated tyrosine phosphorylation that is required for multiple functional responses. This cell line, designated B6A4C1, is deficient in both Fc epsilon RI-mediated degranulation and biosynthesis of several lipid raft components. Agents that bypass receptor-mediated Ca(2+) influx stimulate strong degranulation responses in these variant cells. Cross-linking of IgE-Fc epsilon RI on these cells stimulates robust tyrosine phosphorylation but fails to mobilize a sustained Ca(2+) response. Fc epsilon RI-mediated inositol phosphate production is not detectable in these cells, and failure of adenosine receptors to mobilize Ca(2+) suggests a general deficiency in stimulated phospholipase C activity. Antigen stimulation of phospholipases A(2) and D is also defective. Infection of B6A4C1 cells with vaccinia virus constructs expressing constitutively active Rho family members Cdc42 and Rac restores antigen-stimulated degranulation, and active Cdc42 (but not active Rac) restores ganglioside and GPI expression. The results support the hypothesis that activation of Cdc42 and/or Rac is critical for Fc epsilon RI-mediated signaling that leads to Ca(2+) mobilization and degranulation. Furthermore, they suggest that Cdc42 plays an important role in the biosynthesis and expression of certain components of lipid rafts.

AVALIAÇÃO DE SAÚDE E DA DOR NO PÓS-OPERATÓRIO DE IDOSOS SUBMETIDOS À CIRURGIA CARDÍACA

Directory of Open Access Journals (Sweden)

Thaiza Teixeira Xavier

2011-01-01

Full Text Available El presente estudio tiene como objetivo evaluar la salud y el dolor en pacientes ancianos con insuficiencia coronaria sometidos a cirugía cardíaca. Esta es una investigación de carácter analítico, transversal, con enfoque cuantitativo. La recolección de los datos se hizo por medio de una ficha de evaluación fisioterapéutica usando también la escala numérica de dolor, con 70 pacientes ancianos sometidos a cirugía cardíaca en dos hospitales en la ciudad de Natal/RN, Brasil. El rango de edad más frecuente fue de 60 a 69 años (61,43%, mayoría hombres (62,86%. En relación con el estado de salud el 61,43% de los sujetos tenían enfermedades preexistentes, siendo la de mayor distribución la hipertensión arterial (31.40%. El comportamiento del dolor fue moderado en el 1º y 3º días, y leve en el 2º y 4º días después de la operación. Por lo tanto, se constató que la mayoría de los pacientes ancianos sometidos a cirugía cardíaca eran del sexo masculino, que tenían patologías preexistentes, con la hipertensión arterial como la patología mas frecuente y con predominio de la intensidad del dolor moderado

Prevalencia de enfermedad celíaca en pacientes con hepatopatías crónicas

OpenAIRE

Crivelli, Adriana N.

2016-01-01

La enfermedad celíaca (EC) es definida como una enteropatía crónica del intestino delgado mediada por mecanismos inmunes, precipitada por la exposición al gluten y prolaminas relacionadas de la dieta, en individuos genéticamente predispuestos. Diversas enfermedades hepáticas pueden asociarse a la EC. El espectro del compromiso hepático en la EC es muy amplio e incluye, entre otros, enfermedad hepática criptogenética (desde leve a severa), hepatitis autoinmune, colangitis esclerosante primaria...

Doença celíaca associada à tireoidite de Hashimoto e síndrome de Noonan

OpenAIRE

Perez,Mariana Ortega; Ciambelli,Giuliano Serafino; Nigri,Alcinda Aranha; Vieira,Marta Wey; Costa,Clóvis Duarte

2010-01-01

OBJETIVO: Relatar o caso clínico de uma criança portadora de doença celíaca, tireoidite de Hashimoto e síndrome de Noonan. DESCRIÇÃO DE CASO: Menina de dez anos e seis meses, branca, apresentando história de diarreia líquida há cinco meses e "aumento da barriga". Ao exame, mostrava peso de 20.580g (p

Effective removal of a range of Ti/Ri plasmids using a pBBR1-type vector having a repABC operon and a lux reporter system.

Science.gov (United States)

Yamamoto, Shinji; Sakai, Ayako; Agustina, Vita; Moriguchi, Kazuki; Suzuki, Katsunori

2018-02-01

Ti and Ri plasmids of pathogenic Agrobacterium strains are stably maintained by the function of a repABC operon and have been classified into four incompatibility groups, namely, incRh1, incRh2, incRh3, and incRh4. Removal of these plasmids from their bacterial cells is an important step in determining strain-specific virulence characteristics and to construct strains useful for transformation. Here, we developed two powerful tools to improve this process. We first established a reporter system to detect the presence and absence of Ti/Ri plasmids in cells by using an acetosyringone (AS)-inducible promoter of the Ti2 small RNA and luxAB from Vibrio harveyi. This system distinguished a Ti/Ri plasmid-free cell colony among plasmid-harboring cell colonies by causing the latter colonies to emit light in response to AS. We then constructed new "Ti/Ri eviction plasmids," each of which carries a repABC from one of four Ti/Ri plasmids that belonged to incRh1, incRh2, incRh3, and incRh4 groups in the suicidal plasmid pK18mobsacB and in a broad-host-range pBBR1 vector. Introduction of the new eviction plasmids into Agrobacterium cells harboring the corresponding Ti/Ri plasmids led to Ti/Ri plasmid-free cells in every incRh group. The Ti/Ri eviction was more effective by plasmids with the pBBR1 backbone than by those with the pK18mobsacB backbone. Furthermore, the highly stable cryptic plasmid pAtC58 in A. tumefaciens C58 was effectively evicted by the introduction of a pBBR1 vector containing the repABC of pAtC58. These results indicate that the set of pBBR1-repABC plasmids is a powerful tool for the removal of stable rhizobial plasmids.

A temperature-dependent structural investigation of electrical transitions in A 3conb2o9 perovskites (A=Ca2+, Sr2+, Ba2+)

International Nuclear Information System (INIS)

Ting, V.; Liu, Y.; Withers, R.L.

2006-01-01

Upon heating, the 1:2 triple perovskites A 3 CoNb 2 O 9 (A=Ca, Sr or Ba) each undergo well-defined insulator to conductor phase transitions at ∼8, ∼126 and ∼325 deg. C, respectively. As the trend in the transition temperatures for these materials does not correlate with the size of the reported band gaps, neutron powder diffraction has been used to investigate if this change in electrical behaviour of the materials was due to a structural phase change. It was found that in the regions of the suspected phase transitions there were only slight perturbations of the structures, namely thermal expansion of the lattices and an apparent muting of the amplitude of the octahedral rotations in the A=Ca and Sr compound at higher temperatures

Riigi dividendid sunnivad äriühinguid laenu võtma / Erik Müürsepp

Index Scriptorium Estoniae

Müürsepp, Erik

2008-01-01

Riik on vähendanud Tallinna Sadamast ja Eesti Energiast võetavate dividendide summat, samas peab näiteks Tallinna Sadam investeeringuteks siiski laenu võtma. Diagramm: Riigi osalusega äriühingutelt võetav dividend on kahanenud

Äriühingutele kuuluvate sõiduautode erakasutuse maksustamine : magistritöö / Lea Tõnnison ; juhendaja Lasse Lehis ; Tartu Ülikool, õigusteaduskond, avaliku õiguse osakond

Index Scriptorium Estoniae

Tõnnison, Lea, 1994-

2018-01-01

Erisoodustuse mõiste, äriühingutele kuuluvate sõiduautode erakasutuse maksustamise vajadus, üldised eesmärgid ja meetodid. Äriühingutele kuuluvate sõiduautode erakasutuse maksustamine Eestis ja teistes riikides (Soome, Läti, Belgia, USA)

Feasibility study on RI biochip Application to detection of risk factors of atherosclerosis

International Nuclear Information System (INIS)

Ko, Kyong Cheol; Choi, Mi Hee; Park, Sang Hyun; Cho, Kyung Hyun; Lee, Ki Teak

2009-01-01

Microarrays can be used to screen thousands of binding events in a parallel and high throughput fashion and are of major importance in discase diagnosis and drug discovery. The use of radioisotope is conventionally regarded as one of the most sensitive detection methods. Atherosclerosis is a common disorder affecting arterial blood vessels. It happens when fat, cholesterol, and other substances made in the arterial blood vessels form a hard substances called plaque. Lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ), a phospholipase A 2 enzyme, is used as a marker for cardiac disease. The detection of Lp-PLA 2 was accomplished by using radioactive [ 3 H-acetyl] PAF as a substrate and a feasibility study on RI biochip application to detection of Lp-PLA 2 , a risk factors of atherosclerosis was performed. Inhibitive activity of a native plant extract was also determined by using the RI biochip. It was found to be applicable to a high-throughput screening of inhibitors for developing atherosclerosis therapeutic agents

197. Trombosis masiva biauricular intervenida mediante cirugía cardíaca con circulación extracorpórea

Directory of Open Access Journals (Sweden)

R. Sánchez Pérez

2012-04-01

Conclusión: Destacamos la importancia del diagnóstico precoz y preciso de la trombosis biauricular con embolismo paradójico en aurícula izquierda a través de fosa oval, en el contexto de trombosis venosa profunda, debido a que puede beneficiarse de la cirugía cardíaca como tratamiento inicial.

Maarjamäe loss (Marienberg) / Robert Gödicke, Nikolai vanem Thamm, Jüri Renter

Index Scriptorium Estoniae

Gödicke, Robert

2004-01-01

5 välisvaadet, üks 1930. aastast; mõisa ajaloost, omanikest, lossi arhitektuurist, interjöörist, pargist; 1975. a. anti loss üle Eesti Ajaloomuuseumile; hoone restaureeriti aastatel 1983-88 (arhitekt Jüri Renter, sisearhitekt Helle Gans)

Pelaksanaan PP RI No.19/2008 Sebagai Acuan Kinerja Camat pada Aspek Pemerintahan dan Pendidikan

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Merry Chairina DM. Sinaga

2015-06-01

Full Text Available This study aims to determine the performance camat in the governance and education, which refers to PP RI No.19 / 2008. Researchers used descriptive method implemented in the District Percut Sei Tuan. The sample was the whole population is with 37 employees and only have a single variable: the implementation of PP RI No.19 / 2008 as a reference to the performance of district head in the governance and education in the District Percut Sei Tuan, Deli Serdang regency. Data collection techniques by observation through the observation either directly or indirectly to the subject under study. In this study the authors conducted interviews with respondents who considered berkopetensi in this study. The results showed that the performance camat in the governance and education, which refers to PP RI No.19 / 2008 can be categorized as good, such as the active role undertaken whenever a meeting / conference with employees and citizens. Often talked about the problem of improving the quality of work and education, an invitation to attend the big day, receiving the proposal / opinion of the district head in the field of government development issues of education, accepted the proposal of the villagers regarding the development of education, and play an active role in. arrangements regarding the education in collaboration with third parties.

How the ACA's Health Insurance Expansions Have Affected Out-of-Pocket Cost-Sharing and Spending on Premiums.

Science.gov (United States)

Glied, Sherry; Solís-Román, Claudia; Parikh, Shivani

2016-09-01

One important benefit gained by the millions of Americans with health insurance through the Affordable Care Act (ACA) is protection from high out-of-pocket health spending. While Medicaid unambiguously reduces out-of-pocket premium and medical costs for low-income people, it is less certain that marketplace coverage and other types of insurance purchased to comply with the law's individual mandate also protect from high health spending. Goal: To compare out-of-pocket spending in 2014 to spending in 2013; assess how this spending changed in states where many people enrolled in the marketplaces relative to states where few people enrolled; and project the decline in the percentage of people paying high amounts out-of-pocket. Methods: Linear regression models were used to estimate whether people under age 65 spent above certain thresholds. Key findings and conclusions: The probability of incurring high out-of-pocket costs and premium expenses declined as marketplace enrollment increased. The percentage reductions were greatest among those with incomes between 250 percent and 399 percent of poverty, those who were eligible for premium subsidies, and those who previously were uninsured or had very limited nongroup coverage. These effects appear largely attributable to marketplace enrollment rather than to other ACA provisions or to economic trends.

Isamaaline tundmus : Eesti ja Soome kirjamees Jüri Tilk ehk Yrjö Virula / Anu Pallas

Index Scriptorium Estoniae

Pallas, Anu, 1960-

2010-01-01

Avaliku elu tegelasest, ajakirjanikust ja karskuskirjanduse rajajast Jüri Tilgast, kes 19. sajandi lõpul töötas aktiivselt üldtuntud rahvajuhtide kõrval, olles ka Ado Grenzsteini lähim aatekaaslane

Uudised : Tüüri esiettekanne Frankfurdis. Corelli Musicult "Jõulud mõisas"

Index Scriptorium Estoniae

2006-01-01

22., 23. ja 24. nov. Frankfurdi Alte Operis esiettekandele tulevast Erkki-Sven Tüüri uuest "Klaverikontserdist". Eesti-Tšiili trio Raivo Tafenau - Meelis Vind - Ricardo Padilla kontsertidest sarja "Mõisaromantika" raames 25. nov. Taagepera lossis Valgamaal, 26. nov. Tõstamaa mõisas Pärnumaal ja 16. dets. Vihterpalu mõisas Harjumaal. Hans Neuenfelsi lavastatud Mozarti ooperist "Idemeneo" Deutsche Operis Berliinis. Inglise ansambli Procol Harumi hiti "A Whiter Shade of Pale" autoriõigustest

Cardiomyopathie du péri-partum prise en charge en milieu ...

African Journals Online (AJOL)

Cardiomyopathie du péri-partum prise en charge en milieu Hospitalier Universitaire de Bobo-Dioulasso : aspects thérapeutiques et évolutifs. S. J-B. Tougouma, A.A. Yaméogo, A. Dembélé, G. Kinda, N.V. Yaméogo, G.R.C. Millogo, J.K. Kologo, A. Héma, Y. Kambiré, L. Savadogo, M.S. Ouédraogo, P. Zabsonré ...

Health-related quality of life determinants in outpatients with heart failure Determinantes de la calidad de vida relacionada a la salud en pacientes atendidos en ambulatorios con insuficiencia cardíaca Determinantes da qualidade de vida relacionada à saúde em pacientes ambulatoriais com insuficiência cardíaca

Directory of Open Access Journals (Sweden)

Viviane Martinelli Pelegrino

2011-06-01

Full Text Available This descriptive and exploratory study analyzed variables associated with health-related quality of life among 130 outpatients. Health-related quality of life was measured through the Minnesota Living with Heart Failure Questionnaire. Significant associations were found between patients’ health-related quality of life and their age (r=-0.177; p=0.044, vitality (r=-0.625; p=Trata-se de estudo descritivo e exploratório que analisou as variáveis associadas à qualidade de vida relacionada à saúde (QVRS, de 130 pacientes com insuficiência cardíaca, em seguimento ambulatorial. A QVRS foi avaliada pelo Minnesota Living with Heart Failure e realizada análise de regressão linear. A média da QVRS foi de 34,9 (dp=24,8; intervalo de 0 a 99. Foram encontradas associações significantes entre a medida da QVRS e idade (r=-0,177; p=0,044, vitalidade (r=-0,625; p=<0,001 e saúde mental (r=-0,672; p=<0,001, domínios do SF-36. A regressão linear mostrou que a gravidade dos sintomas da insuficiência cardíaca, e dois domínios do SF-36, vitalidade e saúde mental, explicaram 54% da variação da medida da QVRS. Controlar os sintomas e manter bem-estar mental é essencial para a manutenção da QVRS e são essenciais para o cuidado eficaz da insuficiência cardíaca.

Püha Jüri võitlus kapitalistliku hüdraga / Priit Hõbemägi, Andrei Hvostov

Index Scriptorium Estoniae

Hõbemägi, Priit, 1957-

2009-01-01

SDE uus esimees Jüri Pihl teatas, et sotsiaaldemokraatidel on alternatiiv seni valitsenud neoliberaalsele ideoloogiale. Autorite hinnangul hakkab J. Pihli vastasseis Reformierakonnaga olema hoopis teistsugune kui Keskerakonnaga

Frequência Cardíaca de Recuperação no Primeiro Minuto no Teste de Caminhada de Seis Minutos em Pacientes com Insuficiência Cardíaca

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Sabrina Lindemberg

2014-03-01

Full Text Available Fundamento: A frequência cardíaca de recuperação no primeiro minuto (FCR1 é um preditor de mortalidade na insuficiência cardíaca (IC, mas seu prognóstico não foi avaliado no teste de caminhada de seis minutos (TC6M nesses pacientes. Objetivo: Esse estudo teve como objetivo determinar a FCR1 no TC6M em pacientes com IC e sua correlação com a distância percorrida em seis minutos (DP6M. Métodos: Protocolo controlado, transversal, com 161 indivíduos, 126 pacientes com IC sistólica estável, divididos em dois grupos (G1 e G2, que receberam ou não β-bloqueador e 35 voluntários no grupo controle (G3 que tiveram a FCR1 registrada no TC6M. Resultados: A FCR1 e a DP6M foram significativamente diferentes nos três grupos. Os valores médios de FCR1 e DP6M foram: FCR1 = 12 ± 14 bpm G1, 18 ± 16 bpm G2 e 21 ± 13 bpm G3; DP6M = 423 ± 102 m G1, G2 396 ± 101 m e 484 ± 96 m G3 (p < 0,05. Os resultados demonstraram uma correlação entre FCR1 e DP6M no G1 (r = 0,3, p = 0,04 e G3 (r = 0,4, p = 0,03, mas não em G2 (r = 0,12, p = 0,48. Conclusão: A resposta da FCR1 foi atenuada em pacientes em uso de βB e mostrou correlação com o TC6M, refletindo uma melhor tolerância ao exercício. A FCR1 após a DP6M parece representar uma alternativa quando os testes de esforço na esteira não são tolerados.

279. El derrame pericárdico postoperatorio en cirugía cardíaca: Incidencia e impacto en los resultados quirúrgicos

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E. Sandoval

2012-04-01

Conclusión: La ecocardiografía es una exploración inocua que permite el diagnóstico rápido de DP potencialmente letal, que tiene un componente medicolegal. Debe realizarse a todo postoperado de cirugía cardíaca.

Measuring and Monitoring in the South African "Kha Ri Gude" Mass Literacy Campaign

Science.gov (United States)

McKay, Veronica

2015-01-01

After many previous failed attempts to reach illiterate adults, the award-winning South African "Kha Ri Gude" mass literacy campaign, launched in 2008, undertook to ensure that learners seized the opportunity to learn--for many adults, this was a "last chance". Written from an insider perspective by the campaign's founding…

Fisher: a program for the detection of H/ACA snoRNAs using MFE secondary structure prediction and comparative genomics – assessment and update

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Tamas Ivica

2008-07-01

Full Text Available Abstract Background The H/ACA family of small nucleolar RNAs (snoRNAs plays a central role in guiding the pseudouridylation of ribosomal RNA (rRNA. In an effort to systematically identify the complete set of rRNA-modifying H/ACA snoRNAs from the genome sequence of the budding yeast, Saccharomyces cerevisiae, we developed a program – Fisher – and previously presented several candidate snoRNAs based on our analysis 1. Findings In this report, we provide a brief update of this work, which was aborted after the publication of experimentally-identified snoRNAs 2 identical to candidates we had identified bioinformatically using Fisher. Our motivation for revisiting this work is to report on the status of the candidate snoRNAs described in 1, and secondly, to report that a modified version of Fisher together with the available multiple yeast genome sequences was able to correctly identify several H/ACA snoRNAs for modification sites not identified by the snoGPS program 3. While we are no longer developing Fisher, we briefly consider the merits of the Fisher algorithm relative to snoGPS, which may be of use for workers considering pursuing a similar search strategy for the identification of small RNAs. The modified source code for Fisher is made available as supplementary material. Conclusion Our results confirm the validity of using minimum free energy (MFE secondary structure prediction to guide comparative genomic screening for RNA families with few sequence constraints.

Eco RI RFLP in the human IGF II gene

Energy Technology Data Exchange (ETDEWEB)

Cocozza, S; Garofalo, S; Robledo, R; Monticelli, A; Conti, A; Chiarotti, L; Frunzio, R; Bruni, C B; Varrone, S

1988-03-25

The probe was a 500 bp cDNA containing exons 2-3 and 4 of the human IGF II gene. The clone was isolated by screening a human liver cDNA library with synthetic oligonucleotides. Eco RI digestion of genomic DNA and hybridization with the IGF II probe detects a two allele polymorphism with allelic fragments of 13.5 kb and 10.5 kb. The frequency was studied 38 unrelated Caucasians: Human IGF II gene was localized on the short arm of chromosome 11 (p15) by in situ hybridization. Codominant segregation was observed in 2 Caucasian families (10 individuals).

Uudised : Eesti muusikalistaarid Euroopas. Tüüri 5.sümfoonia Tallinnas

Index Scriptorium Estoniae

2005-01-01

Koit Toome, Ele Millistver ja Lauri Liiv alustavad 1. detsembril Brnos rahvusvahelises muusikalitrupis "Hairi" proovidega. Esietendus on 26. dets. Iserlohni linnas Saksamaal ning etendusi antakse järgmise aasta 16. aprillini Saksa linnades, Austrias, Šveitsis ja Taanis. Erkki-Sven Tüüri 5. sümfoonia tuleb Eestis esiettekandele 10. dets. Estonia Kontserdisaalis, teose esiettekannet selle aasta veebruaris Stuttgardis dirigeeris Olari Elts

A calcium-dependent protein kinase can inhibit a calmodulin-stimulated Ca2+ pump (ACA2) located in the endoplasmic reticulum of Arabidopsis

Science.gov (United States)

Hwang, I.; Sze, H.; Harper, J. F.; Evans, M. L. (Principal Investigator)

2000-01-01

The magnitude and duration of a cytosolic Ca(2+) release can potentially be altered by changing the rate of Ca(2+) efflux. In plant cells, Ca(2+) efflux from the cytoplasm is mediated by H(+)/Ca(2+)-antiporters and two types of Ca(2+)-ATPases. ACA2 was recently identified as a calmodulin-regulated Ca(2+)-pump located in the endoplasmic reticulum. Here, we show that phosphorylation of its N-terminal regulatory domain by a Ca(2+)-dependent protein kinase (CDPK isoform CPK1), inhibits both basal activity ( approximately 10%) and calmodulin stimulation ( approximately 75%), as shown by Ca(2+)-transport assays with recombinant enzyme expressed in yeast. A CDPK phosphorylation site was mapped to Ser(45) near a calmodulin binding site, using a fusion protein containing the N-terminal domain as an in vitro substrate for a recombinant CPK1. In a full-length enzyme, an Ala substitution for Ser(45) (S45/A) completely blocked the observed CDPK inhibition of both basal and calmodulin-stimulated activities. An Asp substitution (S45/D) mimicked phosphoinhibition, indicating that a negative charge at this position is sufficient to account for phosphoinhibition. Interestingly, prior binding of calmodulin blocked phosphorylation. This suggests that, once ACA2 binds calmodulin, its activation state becomes resistant to phosphoinhibition. These results support the hypothesis that ACA2 activity is regulated as the balance between the initial kinetics of calmodulin stimulation and CDPK inhibition, providing an example in plants for a potential point of crosstalk between two different Ca(2+)-signaling pathways.

Controle da dor no pós-operatório de cirurgia cardíaca: uma breve revisão

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Luciano Ramos de Lima

2008-06-01

Full Text Available Este estudo teve como objetivo identificar as terapêuticas analgésicas para controle da dor no pós-operatório de pacientes submetidos à cirurgia cardíaca e os instrumentos utilizados para mensurar a experiência dolorosa. Trata-se de uma pesquisa bibliográfica realizada por meio de revisão da literatura nas bases de dados eletrônicos LILACS, revistas eletrônicas da SciELO, dissertações e teses. Foram utilizados os descritores analgesia, analgesia controlada pelo paciente, cirurgia cardíaca, avaliação e dor pós-operatória. O levantamento dos dados ocorreu em maio de 2007 e foram selecionados estudos publicados no período de maio de 1997 a maio de 2007. Na análise realizou-se síntese reflexiva dos estudos. Dos 23 estudos levantados foram utilizados 8 artigos e uma dissertação de mestrado. A técnica de analgesia mais utilizada foi a Analgesia Controlada pelo Paciente (ACP e os medicamentos mais utilizado foram os opióides, como a morfina, seguidos por antiflamatórios não esteroidais (AINEs e dipirona. Não foram encontrados estudos que utilizaram a terapêutica não farmacológica. Os instrumentos de avaliação de dor frequentemente utilizados nestes estudos incluíram as escalas unidimensionais como a escala numérica verbal e a escala analógica visual. Ficou também evidenciado que os enfermeiros estão pouco envolvidos em pesquisas que abordam o controle da dor no período pós-operatório de cirurgia cardíaca.

Dental caries prevalence as a product of agriculture and subsistence pattern at the Yean-ri site, South Korea.

Science.gov (United States)

Fujita, H; Hashimoto, H; Shoda, S; Suzuki, T

2011-01-01

Yean-ri human skeletal remains from South Korea have been dated to the fourth to seventh century AD. They have morphological similarities to immigrants of the Yayoi period excavated in northern Kyushu and Yamaguchi prefecture in Japan. The overall dental caries prevalence was 8.1% in the Yean-ri skeletal remains, indicating a much lower prevalence than that of most Yayoi immigrant skeletal remains from Japan, although similar to that of the Kofun people (8.3%) in Japan. There was no significant difference in the dental caries prevalence between the males and females of the same age group, but there were differences in the prevalence by age. The late middle age and elderly males and females had significantly higher dental caries prevalence than the early middle age males and females, indicating increased prevalence with age. Root caries prevalence tended to increase in old age. The percentage of root caries increased, accounting for 80% of all caries in Yean-ri human skeletal remains. Agriculture is believed to have arisen approximately 3,000 years ago in Korea. Therefore, agriculture was practiced during this period, but since the Yean-ri tumuli are from coastal areas, their diet may have retained a significant marine component. Additionally, caries prevalence was not very high in Nukdo human remains (ca. 2100-2000 BC) in Korea. We speculate that they maintained subsistence activities suitable for their environment despite their knowledge of agriculture. This hypothesis is supported by differences in the caries prevalence between excavation sites of the Yayoi and Kofun periods in Japan. Copyright © 2011 S. Karger AG, Basel.

Intervención psicológica en cirugía cardíaca

OpenAIRE

Yalilis Castillero Amador

2007-01-01

La cirugía mayor y en particular la cirugía cardiovascular son una fuente potencial de estrés. Este artículo muestra la efectividad de la preparación psicológica en los pacientes sometidos a cirugía cardíaca. A través de una revisión de la literatura consideramos el impacto, tanto físico como psicológico, que tiene el padecer una enfermedad cardiovascular y el ser sometido a una cirugía del corazón.El corazón es un órgano al que se le atribuye un carácter de primacía en relación con los otros...

Peculiaridades no pós-operatório de cirurgia cardíaca no paciente idoso Peculiaridades en el post operatorio de cirugía cardíaca en el paciente de edad avanzada Peculiarities of post-cardiac surgery care in elderly patients

Directory of Open Access Journals (Sweden)

Paulo de Oliveira Vasconcelos Filho

2004-10-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: O paciente idoso tem características fisiológicas próprias e, muitas vezes, pode apresentar deficiências orgânicas ou afecções graves, que por si, já tornam o pós-operatório complicado. O objetivo deste artigo é apresentar uma revisão das condutas pós-operatórias de cirurgia cardíaca no idoso, apresentando as alterações mais freqüentes nesse tipo de paciente. CONTEÚDO: As condutas no período intra-operatório do paciente idoso devem ser tomadas tendo em vista a diminuição da morbidade pós-operatória. Na chegada do paciente idoso à UTI, devem ser cumpridos os mesmos critérios utilizados na internação de outros pacientes adultos de cirurgia cardíaca, para o serviço ter sempre um padrão, que não leve a uma alteração na rotina e que não provoque equívocos. Estabelecer um plano de cuidados intensivos para o pós-operatório de cirurgia cardíaca irá resultar em uma ótima utilização de recursos da unidade, em efetividade de atenção e em diminuição do tempo nos cuidados em relação ao paciente idoso. Os exames auxiliares solicitados também devem seguir um padrão, estabelecido pelo serviço, a não ser que alterações sejam identificadas. Complicações neurológicas, pulmonares, circulatórias, insuficiência renal, infecção e hipotireoidismo são freqüentes, com particularidades no idoso. Elas estão delineadas neste artigo e devem ser bem compreendidas pelo intensivista que cuida desse tipo de paciente. CONCLUSÕES: As complicações apresentadas neste artigo são as que trazem maior preocupação ao intensivista, quando há um paciente idoso em pós-operatório de cirurgia cardíaca na UTI. Este paciente necessita de cuidados especiais, mesmo quando a cirurgia transcorre em perfeita normalidade, pois o estresse cirúrgico é muito grande e o idoso tem reserva funcional diminuída.JUSTIFICATIVA Y OBJETIVOS: El paciente de edad avanzada tiene características fisiol

Sadamasse lubatud veepargi asemele kerkivad hoopis äri- ja büroohooned / Urmas Seaver

Index Scriptorium Estoniae

Seaver, Urmas, 1973-

2008-01-01

Salto Arhitektuuribüroo ja Urmas Lõokese Arhitektuuribüroo nägemus Tallinnas Admiraliteedi basseini ääres olevast Ahtri 3 kinnistust, kuhu tuleb kaks õhust kulgevate sildadega ühendatud äri- ja büroohoonet. Kommenteerivad Karli Luik ja Endrik Mänd

Interleucina 1β correlaciona-se com MIBG e parâmetros do exercício, na insuficiência cardíaca?

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Leandro Rocha Messias

2013-05-01

Full Text Available FUNDAMENTO: Na insuficiência cardíaca, níveis de interleucina 1β (IL 1β se associam a prognóstico. A atividade adrenérgica cardíaca avaliada através da cintilografia com metiodobenzilguanidina (I123 MIBG e parâmetros do exercício são importantes preditores de prognóstico. A relação entre essas variáveis não está bem definida. OBJETIVO: Avaliar associação entre níveis de IL 1β com parâmetros do exercício e do I123 MIBG. MÉTODOS: Estudo observacional transversal, com avaliação de 25 pacientes consecutivos com insuficiência cardíaca e fração de ejeção menor que 45%, através de: dosagem de IL 1β; parâmetros do I123 MIBG [relação coração/mediastino precoce e tardia, taxa de washout (WO]; e teste ergométrico em esteira pelo protocolo de Rampa. RESULTADOS: Separados em dois grupos pelos níveis de IL 1β (normal vs. elevado, o grupo com níveis aumentados apresentava menor reserva de duplo produto (RDP, menor capacidade funcional (CF e recuperação mais lenta da frequência cardíaca no 1º (RFC 1º e 2º minuto (RFC 2º, e maior WO. Na análise univariada, todas as variáveis se correlacionaram com a IL 1β; RDP: r = 0,203, p = 0,024; CF: r = 0,181, p = 0,034; RFC 1º: r = 0,182, p = 0,034; RFC 2º: r = 0,204, p = 0,023; WO: r = 0,263, p = 0,009. Na multivariada, apenas a WO permaneceu com correlação significativa (r2 = 0,263, p = 0,009. CONCLUSÃO: A hipertonia adrenérgica foi o principal determinante dos níveis de IL 1β, demonstrando que a atividade simpática excessiva influencia a atividade inflamatória sistêmica. As variáveis do teste ergométrico não foram capazes de identificar pacientes com níveis elevados de IL 1β.

Há evidências favorecendo o uso de betabloqueadores e dobutamina na insuficiência cardíaca aguda?

Directory of Open Access Journals (Sweden)

Luiz Carlos Santana Passos

2013-02-01

Full Text Available Diversos estudos relataram os benefícios dos betabloqueadores (BB para pacientes com insuficiência cardíaca sistólica. No entanto, muitos pacientes hospitalizados em decorrência de insuficiência cardíaca aguda já estão usando os BB e requerem dobutaminas para hipotensão arterial e baixo débito cardíaco. Portanto, deve-se tomar uma decisão a respeito de se o BB deve ser mantido ou até mesmo iniciado nesses casos. O objetivo deste estudo foi determinar se há provas que sustentem a segurança e a eficácia dos BB junto com a dobutamina para pacientes com insuficiência cardíaca aguda descompensada (ICAD. Foi realizada uma pesquisa na literatura de língua inglesa nas bases de dados MEDLINE, ISI Web of Science, Biblioteca Virtual em Saúde, Cochrane Library e o Portal de Revistas Científicas do Capes para identificar estudos relacionados. Literatura adicional foi obtida mediante a análise das respectivas referências encontradas nos artigos identificados. Os resultados esperados incluíram informações sobre o prognóstico (intra-hospitalar e na mortalidade no acompanhamento, número de dias de internação e reinternação, eficácia e segurança (agravamento dos sintomas, choque, intolerância do uso concomitante desses medicamentos em pacientes hospitalizados com ICAD e baixo débito cardíaco. Esta análise incluiu nove estudos. No entanto, não foram encontrados ensaios clínicos randomizados sobre o assunto. A maioria dos estudos inclui baixo número de pacientes, e não foram encontrados estudos que abordem a segurança do uso concomitante desses medicamentos. Os dados resultantes sugerem que uma cuidadosa revisão da literatura não forneceu evidências para o uso sistemático de BB em pacientes com síndrome de baixo débito cardíaco que necessitam de suporte inotrópico com dobutamina.

Origem, ramificação e distribuição da artéria celíaca no tucano-de-bico-verde (Ramphastos dicolorus Linnaeus, 1766

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Osório J. Silva Neto

2013-03-01

Full Text Available O tucano-de-bico-verde (Ramphastos dicolorus é uma ave encontrada nas florestas tropicais americanas e pertence à Ordem Piciforme, Família Ramphastidae. Neste trabalho objetivou-se descrever a origem, a ramificação e a distribuição da artéria celíaca do tucano-de-bico-verde. Foram utilizados três espécimes provenientes do Criatório Científico e Cultural de Poços de Caldas, MG (IBAMA, 2.31.94-00006, doados após óbito por causas naturais. As aves tiveram a artéria isquiática direita canulada para injeção de solução de látex corado, e após fixação em solução de formol a 10% foram dissecadas. A artéria celíaca originou-se a partir da porção descendente da aorta, emitindo como primeiro ramo colateral a artéria pró-ventricular dorsal. Esta emitiu ramos esofágicos e continuou-se como artéria gástrica dorsal, de aspecto tortuoso, terminando em anastomose com a artéria gástrica direita. Após curto trajeto, a artéria celíaca formou dois ramos colaterais, o esquerdo e o direito. O ramo esquerdo logo se ramificou formando a artéria pró-ventricular ventral com seus ramos esofágicos, artéria gástrica esquerda, que originou a artéria hepática esquerda, e finalmente a artéria gastroduodenal, que emitiu as artérias gástricas ventrais e duodenais. O ramo direito da artéria celíaca emitiu as artérias lienais e hepática direita, continuando-se como artéria pancreático-duodenal. Esta formou a artéria pilórica dorsal, duas artérias gástricas direitas, vários ramos duodenais, pancreáticos e a artéria duodeno-jejunal. Assim, a artéria celíaca nos três espécimes de tucano-de-bico-verde, exibiu um arranjo que se assemelha tanto ao descrito em aves domésticas quanto ao de aves silvestres.

Beam optics simulation of rare-RI ring at RI beam factory in RIKEN

International Nuclear Information System (INIS)

Arai, I.; Ozawa, A.; Yasuda, Y.

2009-01-01

The cyclotron-like storage ring dedicated to Rare-RI Ring project consists of 6 magnetic sectors and 6 straight sections, having a circumference of 56.13 m. The magnetic sector works for both bending and focusing. The total circulation is assumed to be 1,000 turns. Over the momentum range from -1% to +1% in ∆p/p, the required isochronicity is 10 -6 while the beam emittance is several tens of π mm-mrad. To examine the design of cyclotron-like storage ring and fix its parameters, we have developed a high precision beam optics simulation. To achieve the precision as high as possible within a feasible computational time, we have adopted a geometrical tracking assuming a circular orbit for a small spatial segment. For that purpose, it is enough that the magnetic sector is divided into 150 sub-sectors in calculation. In each sub-sector, the magnetic field is given as a function of radial position but uniform around the vicinity of beam trajectory. The beam trajectory is evaluated in 4th order Runge-Kutta algorithm. Finally, we have achieved a precision of 10 -9 in ∆T/T and a computational time of 1.8 sec on a typical PC server for ray tracing of single particle undergoing a circulation of 1,000 turns. (author)

Contusión cardíaca: Informe de 4 casos

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Andrés Cazau Cuervo

1997-04-01

Full Text Available Se presentaron 4 pacientes del sexo masculino (historias clínicas números 767 451, 898 039, 606 959 y 780 349, con antecedentes, hallazgos físicos y métodos diagnósticos positivos de contusión cardíaca, los cuales fueron atendidos en el Centro de Urgencias del Hospital (Instituto Superior de Medicina Militar "Luis Díaz Soto" entre el 25 de octubre de 1989 y el 12 de febrero de 1990. El paciente más joven tenía 18 años y el más viejo 64. Los 4 pacientes presentaron síntomas variables de contusión cardíaca. El dolor retroesternal fue la manifestación clínica más constante. De los métodos utilizados para el diagnóstico, las alteraciones del segmento ST y de la onda T en los electrocardiogramas y la elevación en el suero de la fracción MB de la creatina fosfoquinasa por encima del 5 % fueron los elementos de mayor valor para el diagnóstico. Los indicadores pronósticos fueron de 20 en los casos 1, 2 y 3 (severo sin peligro de muerte y en el cuarto fue de 34 (severo con peligro de muerte. Todos los enfermos evolucionaron favorablementeFour male patients (medical records 767 451, 898 039, 606 959, and 780 349 presenting with clinical histories, physical findings, and positive diagnostic methods evidencing a cardiac contusion were attended at the Emergency Department of "Luis Díaz Soto" Higher Institute of Military Medicine between October 25, 1989 and February 12, 1990. The youngest patients was 18 years old and the oldest 64 years old. The four patients presented with different symptoms suggesting a cardiac contusion. The retrosternal pain was the principal clinical manifestation. From the methods used for the diagnosis, alterations of the ST segment and of the T wave in the electrocardiograms and the rise in serum MB fraction of creatine phosphokinase above 5 % were found to be the most useful elements for the diagnosis. The prognostic indicators were 20 in cases 1, 2, and 3 (severe with no risk of death and in case 4 were 34

Metoodika väljatöötamine konfliktide uurimiseks äriühingute valitsemisel / Kristo Viksi

Index Scriptorium Estoniae

Viksi, Kristo

2005-01-01

2004. a. Eesti erialases ajakirjanduses ilmunud artiklite analüüsist, millest selgus, millised konfliktid esinevad Eesti äriühingute valitsemises, millised on nende tunnused ja kuidas neid on lahendatud

Arabidopsis calmodulin-like protein CML36 is a calcium (Ca2+) sensor that interacts with the plasma membrane Ca2+-ATPase isoform ACA8 and stimulates its activity.

Science.gov (United States)

Astegno, Alessandra; Bonza, Maria Cristina; Vallone, Rosario; La Verde, Valentina; D'Onofrio, Mariapina; Luoni, Laura; Molesini, Barbara; Dominici, Paola

2017-09-08

Calmodulin-like (CML) proteins are major EF-hand-containing, calcium (Ca 2+ )-binding proteins with crucial roles in plant development and in coordinating plant stress tolerance. Given their abundance in plants, the properties of Ca 2+ sensors and identification of novel target proteins of CMLs deserve special attention. To this end, we recombinantly produced and biochemically characterized CML36 from Arabidopsis thaliana We analyzed Ca 2+ and Mg 2+ binding to the individual EF-hands, observed metal-induced conformational changes, and identified a physiologically relevant target. CML36 possesses two high-affinity Ca 2+ /Mg 2+ mixed binding sites and two low-affinity Ca 2+ -specific sites. Binding of Ca 2+ induced an increase in the α-helical content and a conformational change that lead to the exposure of hydrophobic regions responsible for target protein recognition. Cation binding, either Ca 2+ or Mg 2+ , stabilized the secondary and tertiary structures of CML36, guiding a large structural transition from a molten globule apo-state to a compact holoconformation. Importantly, through in vitro binding and activity assays, we showed that CML36 interacts directly with the regulative N terminus of the Arabidopsis plasma membrane Ca 2+ -ATPase isoform 8 (ACA8) and that this interaction stimulates ACA8 activity. Gene expression analysis revealed that CML36 and ACA8 are co-expressed mainly in inflorescences. Collectively, our results support a role for CML36 as a Ca 2+ sensor that binds to and modulates ACA8, uncovering a possible involvement of the CML protein family in the modulation of plant-autoinhibited Ca 2+ pumps. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

Pihl : joobes autojuhtimised pole liikluses probleem number üks / Jüri Pihl ; interv. Peeter Kuimet

Index Scriptorium Estoniae

Pihl, Jüri, 1954-

2007-01-01

Siseminister Jüri Pihl vastab küsimustele liiklusõnnetuste ja -surmade põhjuste kohta, pidades suurimaks põhjuseks kiiruseületamist ja lahtisi turvavöid. Rikkujate karistamisest ja alkoholimüügi piirangutest. Lisa: Kurb statistika

Grupo de pacientes de cirurgia cardíaca: relato de experiência

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Elisa Helena Kuhn

1986-09-01

Full Text Available Neste trabalho relata-se uma experiência de grupo com pacientes de cirurgia cardíaca. A atividade realiza-se no INSTITUTO DE CARDIOLOGIA DO RIO GRANDE DO SUL e tem por objetivo proporcionar aos pacientes a oportunidade de verbalizarem suas ansiedades e conversarem sobre suas experiências relacionadas com a cirurgia e anestesia. Os grupos reúnem-se duas vezes por semana sendo constituídos por pacientes adultos em pré e pós-operatório imediato. A equipe de saúde é composta por enfermeiros, psicólogo, anestesista, cardiologistas e fisioterapeutas e sua atuação é no sentido de auxiliar na compreensão dos procedimentos aos quais o paciente vai se submeter, desfazendo fantasias distorcidas da realidade.

IL-1RI (Interleukin-1 Receptor Type I Signalling is Essential for Host Defence and Hemichannel Activity During Acute Central Nervous System Bacterial Infection

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Juan Xiong

2012-03-01

Full Text Available Staphylococcus aureus is a common aetiological agent of bacterial brain abscesses. We have previously established that a considerable IL-1 (interleukin-1 response is elicited immediately following S. aureus infection, where the cytokine can exert pleiotropic effects on glial activation and blood–brain barrier permeability. To assess the combined actions of IL-1α and IL-1β during CNS (central nervous system infection, host defence responses were evaluated in IL-1RI (IL-1 receptor type I KO (knockout animals. IL-1RI KO mice were exquisitely sensitive to intracerebral S. aureus infection, as demonstrated by enhanced mortality rates and bacterial burdens within the first 24 h following pathogen exposure compared with WT (wild-type animals. Loss of IL-1RI signalling also dampened the expression of select cytokines and chemokines, concomitant with significant reductions in neutrophil and macrophage infiltrates into the brain. In addition, the opening of astrocyte hemichannels during acute infection was shown to be dependent on IL-1RI activity. Collectively, these results demonstrate that IL-1RI signalling plays a pivotal role in the genesis of immune responses during the acute stage of brain abscess development through S. aureus containment, inflammatory mediator production, peripheral immune cell recruitment, and regulation of astrocyte hemichannel activity. Taken in the context of previous studies with MyD88 (myeloid differentiation primary response gene 88 and TLR2 (Toll-like receptor 2 KO animals, the current report advances our understanding of MyD88-dependent cascades and implicates IL-1RI signalling as a major antimicrobial effector pathway during acute brain-abscess formation.

Resincronización en el postoperatorio de cirugía cardíaca. ¿Podría tener alguna utilidad? Resultados preliminares

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Enrique Oliva de Anquín

2006-01-01

Conclusiones: Debería tenerse en cuenta el posible efecto negativo de la estimulación sobre la función ventricular a la hora de decidir localización y tipo de estimulación en el postoperatorio de cirugía cardíaca.

Diagnósticos de enfermagem em pacientes no período pós-operatório de cirurgias cardíacas Diagnósticos de enfermería en pacientes en el período postoperatorio de cirugías cardíacas Nursing diagnoses in patients in the postoperative period of cardiac surgery

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Flávia Lamberti Pivoto

2010-10-01

Full Text Available OBJETIVO: Identificar, em conjunto com enfermeiras de uma Unidade de Tratamento Intensivo Pós-Operatória Cardiológica, diagnósticos de enfermagem presentes em pacientes no período pós-operatório de cirurgias cardíacas, com vistas à futura implementação do processo de enfermagem nessa unidade. MÉTODOS: Trata-se de um estudo qualitativo, ancorado na pesquisa convergente-assistencial. Os dados foram obtidos, nos registros de enfermagem de 20 pacientes submetidos à cirurgia cardíaca, no mês de abril de 2008, acrescidos da experiência profissional de seis enfermeiras participantes do grupo de convergência reunido durante cinco encontros. RESULTADOS: Foram estabelecidos 15 diagnósticos, segundo a Taxonomia II da North American Nursing Diagnosis Association, corroborados por outros autores. CONCLUSÃO: Identificar diagnósticos de enfermagem comuns em pacientes no pós-operatório de cirurgias cardíacas permite um direcionamento da assistência de enfermagem e subsidia o estabelecimento de intervenções fundamentadas e adequadas às necessidades individuais apresentadas por esses pacientes.OBJETIVO: Identificar en conjunto con las enfermeras, de una Unidad de Tratamiento Intensivo Postoperatorio Cardiológico, los diagnósticos de enfermería realizados en pacientes en el período postoperatorio de cirugías cardíacas, con la finalidad de, futuramente, implementar el proceso de enfermería en esa unidad. MÉTODOS: Se trata de un estudio cualitativo, basado en la investigación convergente-asistencial. Los datos fueron obtenidos de los registros de enfermería de 20 pacientes sometidos a cirugía cardíaca, en el mes de abril de 2008, acrecidos de la experiencia profesional de seis enfermeras participantes del grupo de convergencia que se reunió durante cinco encuentros. RESULTADOS: Fueron establecidos 15 diagnósticos, según la Taxonomía II de la North American Nursing Diagnosis Association, corroborados por otros autores

Poliglobulia e hidronefrosis de riñón en herradura

OpenAIRE

Gómez-Ferrer Lozano, A.; Navarro Antón, J.A.; Mola Arizo, M.J.; Polo i Peris, A.C.

2005-01-01

Presentamos el caso clínico de un paciente en el que se asoció eritrocitosis e hidronefrosis del hemirriñón derecho de un riñón en herradura. El paciente presentaba hidronefrosis masiva avanzada secundaria a obstrucción pieloureteral ocupando todo el hemiabdomen derecho. Después de la nefrectomía la masa eritrocitaria descendió a valores normales. La poliglobulia secundaria puede ser debida a una producción inadecuada de eritropoyetina y se ha descrito en asociación con patología renal de div...

Pesquisa de gliadina em medicamentos: informação relevante para a orientação de pacientes com doença celíaca

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SDEPANIAN Vera Lucia

2001-01-01

Full Text Available Racional - Alguns medicamentos podem conter gliadina, portanto, sua utilização poderá ser prejudicial aos pacientes com doença celíaca. Objetivo - Detectar a presença de gliadina em medicamentos comumente comercializados no Brasil. Métodos - Foram analisados 78 medicamentos sorteados a partir de uma lista de 180 produtos comumente comercializados. Os medicamentos analisados foram: analgésicos (n = 9, anti-helmínticos (n = 3, antiácidos (n = 8, antibióticos (n = 13, anticolesterolêmicos (n = 1, anticonvulsivantes (n = 2, antidepressivos (n = 2, antidiabéticos (n = 1, antieméticos (n = 3, anti-hipertensivos (n = 3, anti-histamínicos (n = 3, antiinflamatórios (n = 7, antitérmicos (n = 2, broncodilatadores (n = 1, descongestionantes (n = 4, laxantes (n = 1, contraceptivos orais (n = 5 e vitaminas (n = 10. As amostras foram analisadas pela técnica de ELISA utilizando anticorpo monoclonal ômega-gliadina, considerada de eleição segundo o Codex Alimentarius Commission WHO/FAO. Todas as amostras foram analisadas em duplicata. O nível de detecção do teste é de 4 mg de gliadina/100 g de produto. Resultados - Dentre os 78 medicamentos analisados, em apenas 1 (1,3% foi detectada a presença de gliadina (5,5 mg/100 g. O componente ativo do medicamento é ranitidina. De acordo com o Codex Alimentarius Commission WHO/FAO, o limite máximo diário permitido ao consumo pelos indivíduos com doença celíaca é igual a 10 mg de gliadina. Considerando a quantidade de gliadina num único comprimido de ranitidina, a quantidade ingerida seria bem menor do que a máxima permitida ao consumo pelo paciente com doença celíaca. Conclusões - Neste estudo não foi identificada gliadina em medicamentos em quantidade que constitua risco para pacientes com doença celíaca.

Subthreshold Desensitization of Human Basophils Re-capitulates the Loss of syk and FcεRI expression Characterized by Other Methods of Desensitization

Science.gov (United States)

MacGlashan, Donald

2012-01-01

Background Clinical desensitization of patients to drugs involves progressive exposure to escalating doses of drug over a period of 24 hours. In prior studies, this method was recapitulated in vitro to also demonstrate loss of mast cell or basophil responsiveness. However, most signaling studies of human basophils have identified changes in signaling by using other methods of inducing cellular desensitization. Objective This study examined two well-described endpoints of basophil desensitization, loss of syk or FcεRI expression, under conditions of subthreshold desensitization. Methods The loss of FceRI and syk was examined in human basophils. Results It was shown that both loss of syk and FcεRI/IgE occurred during an escalating series of stimulation (anti-IgE Ab) and that expression loss occurred despite the presence of little histamine release. If basophils were first cultured for 3 days in 10 ng/ml IL-3, the concentration-dependence of histamine release shifted to 100 fold lower concentrations of stimulus. However, loss of syk did not show any change in its EC50 while loss of FcεRI also shifted 100 fold. From the perspective of early signal element activation, the marked shift in the EC50 for histamine release was not accompanied by similar shifts in the EC50s for several signaling elements. The EC50s for phospho-Src, phospho-SHIP1, phospho-Syk, or phospho-Cbl did not change while the EC50s for phospho-Erk and the cytosolic calcium response did shift 100 fold. Conclusions These studies show that under normal conditions, subthreshold desensitization leads to loss of two critical signaling molecules (FcεRI and syk) but under at least one condition, treatment with IL-3, it is possible to markedly blunt the loss of syk, but not FcεRI, while executing a proper subthreshold titration. These data also suggest that IL-3 modifies only the sensitivity of signaling elements that are downstream of syk activation. PMID:22702505

Establishing a comprehensive risk assessment document for Fernald

International Nuclear Information System (INIS)

Nelson, K.A.; Janke, R.C.

1995-01-01

While in active operation from 1952 until 1989, the Feed Material Production Center (FMPC),currently referred to as the Fernald Environmental Management Project (FEMP), produced highly purified uranium metal for ultimate use in the manufacture of nuclear weapons. In 1986 the U.S. Environmental Protection Agency (EPA) and the DOE entered into a Federal Facility Compliance Agreement covering environmental impacts associated with the FMPC. In response to the FFCA, a sitewide Remedial Investigation/Feasibility Study (RI/FS) was initiated. Production was permanently suspended at the facility in 1989, and the focus has since shifted to environmental restoration and waste management activities. The original RI/FS work plan identified 39 units, but these were later categorized and grouped into 5 larger, more manageable units as follows: (1) operable unit 1 - waste pit area; (2) operable unit 2 - other solid waste units; (3) operable unit 3 - former production area; (4) operable unit 4- silos I through 4; and (5) operable unit 5 - environmental media. On June 29, 1990, a consent agreement (under Sec. 120 and 106[a] of CERCLA) between the DOE and EPA became effective. The purpose of this agreement was to achieve consistency between the operable units and ensure commitments to the RI/FS program without altering the underlying objectives. The consent agreement was amended the following year to revise the schedules for completing the remediation of the five operable units and to direct operable unit integration to ensure compliance with the residual risk requirements of the National Hazardous Substances and Oil Contingency Plan. This Amended Consent Agreement (ACA) was signed on September 20, 1991, and became effective on December 19, 1991. In accordance with provisions of the ACA, a methodology has been prepared for performing risk assessments and establishing risk-based remedial action goals at the FEMP

Uudised : Lassmann Konservatooriumide Assotsiatsiooni juhatuses. Algab "Con brio 2000". Erkki-Sven Tüüri autorikontsert / Annika Koppel

Index Scriptorium Estoniae

Koppel, Annika

2000-01-01

P. Lassmann valiti Euroopa Konservatooriumide Assotsiatsiooni juhatuse liikmeks. Eesti noorte interpreetide konkurssfestivalist "Con brio 2000". Tallinna metodisti kirikus toimub 24. nov. E.-S. Tüüri autorikontsert

Exchangeability of RI image data and its effect

Energy Technology Data Exchange (ETDEWEB)

Kojima, K; Hiraki, T [Kanazawa Univ. (Japan). School of Paramedicine; Nakajima, K; Hisada, K; Yamada, M

1981-10-01

Of RI image data processing machines, the exchangeability of data between the VIP-450 system (Ohio-Nuclear Inc.) and the DAP-5000N system (Toshiba Co.) was examined. The exchangeability requires uniformity of arrangement of bits and the data sequence between the machines. Otherwise, the form of memory of either machine should be changed. The exchangeability of data between the machines would have the following advantages: characteristic programs of each machine can be used for the same data, producing more valuable information. Data collection can be performed by any machine, increasing the efficiency of examination. It is not necessary to provide all machines with special attachments. It permits data input into large machines or minicomputers in the development of programs.

Exchangeability of RI image data and its effect

International Nuclear Information System (INIS)

Kojima, Kazuhiko; Hiraki, Tatsunosuke; Nakajima, Kenichi; Hisada, Kinichi; Yamada, Masato.

1981-01-01

Of RI image data processing machines, the exchangeability of data between the VIP-450 system (Ohio-Nuclear Inc.) and the DAP-5000N system (Toshiba Co.) was examined. The exchangeability requires uniformity of arrangement of bits and the data sequence between the machines. Otherwise, the form of memory of either machine should be changed. The exchangeability of data between the machines would have the following advantages: characteristic programs of each machine can be used for the same data, producing more valuable information. Data collection can be performed by any machine, increasing the efficiency of examination. It is not necessary to provide all machines with special attachments. It permits data input into large machines or minicomputers in the development of programs. (Chiba, N.)

Cardiac response and anxiety levels in psychopathic murderers Resposta cardíaca e nível de ansiedade em homicidas psicopatas

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Antonio de Pádua Serafim

2009-09-01

Full Text Available OBJECTIVE: To compare the emotional response and level of anxiety of psychopathic murderers, non-psychopathic murderers, and nonpsychopathic non-criminals. METHOD: 110 male individuals aged over 18 years were divided into three groups: psychopathic murderers (n = 38; non-psychopathic murderers (n = 37 serving sentences for murder convictions in Maximum Security Prisons in the State of Sao Paulo; and non-criminal, non-psychopathic individuals (n = 35 according to the Psychopathy Checklist-Revised. The emotional response of subjects was assessed by heart rate variation and anxiety level (State-Trait Anxiety Inventory after viewing standardized pictures depicting pleasant, unpleasant and neutral content from the International Affective Picture System. RESULTS: Psychopathic murderers presented lower anxiety levels and smaller heart rate variations when exposed to pleasant and unpleasant stimuli than nonpsychopathic murderers or non-psychopathic non-criminals. The results also demonstrated that the higher the score for factor 1 on the Psychopathy Checklist-Revised, the lower the heart rate variation and anxiety level. CONCLUSION: The results suggest that psychopathic murderers do not present variation in emotional response to different visual stimuli. Although the non-psychopathic murderers had committed the same type of crime as the psychopathic murderers, the former tended to respond with a higher level of anxiety and heart rate variation.OBJETIVO: Comparar a atividade cardíaca e nível de ansiedade de homicidas psicopatas e não psicopatas e não criminosos não psicopatas. MÉTODO: 110 homens com idade superior a 18 anos, divididos em três grupos: homicidas psicopatas (n = 38, homicidas não psicopatas (n = 37 cumprindo pena por homicídio em Prisões de Segurança Máxima do Estado de São Paulo e não criminosos e não psicopatas (n = 35 de acordo com a Escala de Avaliação de Psicopatia. A resposta emocional foi avaliada pela variação da

The Effect of Spiromesifen on the Reproductive Potential of Tetranychus urticae Koch (Acari: Tetranychidae

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Dejan Marčić

2009-01-01

Full Text Available Laboratory bioassays were conducted to evaluate the effects of spiromesifen on the fecundity, fertility and population growth of two-spotted spider mite (Tetranychus urticae Koch after treatment of pre-ovipositing females with five acaricide concentrations: 180mg/l (maximum recommended concentration for use in glasshouses against spider mites, 18 mg/l, 1.8 mg/l and 0.18 mg/l (the last one was discriminative for eggs and immatures in preliminary studies, i.e. produced 100% mortality of those stages and 0.018 mg/l. After24h exposure, the percentages of females surviving treatment without visible symptoms of poisoning were 50% (180 mg/l, 45% (18 mg/l, 51% (1.8 mg/l, 74% (0.18 mg/l, 96% (0.018 mg/l and 98% (0 mg/l. Over the first four days after treatment, the females that survived180 mg/l and 18 mg/l laid no eggs. The total number of eggs laid after treatment with these two concentrations was reduced to less than 2% against the control by the end of the trial. The females that survived 1.8 mg/l laid 50% less eggs, compared to the control, while the number of eggs laid by the females treated with 0.18 mg/l and 0.018 mg/l were 19% and 4% lower, respectively. Over the initial four days, egg hatch rates in treatments were 73-87%, and 92-93% in the control. Significant statistical differences between gross fecundity (FCg and gross fertility (FTg values in the control and treatments were detected for females surviving 180 mg/l, 18 mg/l and 1.8 mg/l. On the other hand, only the net fertility (FTn value of females treated with 0.018 mg/l showed no statistically significant difference from the control value. Treatments with 180 mg/l and 18 mg/l significantly reduced the instantaneous rate of increase (ri 6, 8 and 10 days after treatment, compared to the control. The negative ri values in those treatments indicated a declining population. Sublethal effects of spiromesifen and its impact on T. urticae management are discussed.

Assessment of statistic analysis in non-radioisotopic local lymph node assay (non-RI-LLNA) with α-hexylcinnamic aldehyde as an example

International Nuclear Information System (INIS)

Takeyoshi, Masahiro; Sawaki, Masakuni; Yamasaki, Kanji; Kimber, Ian

2003-01-01

The murine local lymph node assay (LLNA) is used for the identification of chemicals that have the potential to cause skin sensitization. However, it requires specific facility and handling procedures to accommodate a radioisotopic (RI) endpoint. We have developed non-radioisotopic (non-RI) endpoint of LLNA based on BrdU incorporation to avoid a use of RI. Although this alternative method appears viable in principle, it is somewhat less sensitive than the standard assay. In this study, we report investigations to determine the use of statistical analysis to improve the sensitivity of a non-RI LLNA procedure with α-hexylcinnamic aldehyde (HCA) in two separate experiments. Consequently, the alternative non-RI method required HCA concentrations of greater than 25% to elicit a positive response based on the criterion for classification as a skin sensitizer in the standard LLNA. Nevertheless, dose responses to HCA in the alternative method were consistent in both experiments and we examined whether the use of an endpoint based upon the statistical significance of induced changes in LNC turnover, rather than an SI of 3 or greater, might provide for additional sensitivity. The results reported here demonstrate that with HCA at least significant responses were, in each of two experiments, recorded following exposure of mice to 25% of HCA. These data suggest that this approach may be more satisfactory--at least when BrdU incorporation is measured. However, this modification of the LLNA is rather less sensitive than the standard method if employing statistical endpoint. Taken together the data reported here suggest that a modified LLNA in which BrdU is used in place of radioisotope incorporation shows some promise, but that in its present form, even with the use of a statistical endpoint, lacks some of the sensitivity of the standard method. The challenge is to develop strategies for further refinement of this approach

Assessment of statistic analysis in non-radioisotopic local lymph node assay (non-RI-LLNA) with alpha-hexylcinnamic aldehyde as an example.

Science.gov (United States)

Takeyoshi, Masahiro; Sawaki, Masakuni; Yamasaki, Kanji; Kimber, Ian

2003-09-30

The murine local lymph node assay (LLNA) is used for the identification of chemicals that have the potential to cause skin sensitization. However, it requires specific facility and handling procedures to accommodate a radioisotopic (RI) endpoint. We have developed non-radioisotopic (non-RI) endpoint of LLNA based on BrdU incorporation to avoid a use of RI. Although this alternative method appears viable in principle, it is somewhat less sensitive than the standard assay. In this study, we report investigations to determine the use of statistical analysis to improve the sensitivity of a non-RI LLNA procedure with alpha-hexylcinnamic aldehyde (HCA) in two separate experiments. Consequently, the alternative non-RI method required HCA concentrations of greater than 25% to elicit a positive response based on the criterion for classification as a skin sensitizer in the standard LLNA. Nevertheless, dose responses to HCA in the alternative method were consistent in both experiments and we examined whether the use of an endpoint based upon the statistical significance of induced changes in LNC turnover, rather than an SI of 3 or greater, might provide for additional sensitivity. The results reported here demonstrate that with HCA at least significant responses were, in each of two experiments, recorded following exposure of mice to 25% of HCA. These data suggest that this approach may be more satisfactory-at least when BrdU incorporation is measured. However, this modification of the LLNA is rather less sensitive than the standard method if employing statistical endpoint. Taken together the data reported here suggest that a modified LLNA in which BrdU is used in place of radioisotope incorporation shows some promise, but that in its present form, even with the use of a statistical endpoint, lacks some of the sensitivity of the standard method. The challenge is to develop strategies for further refinement of this approach.

77 FR 7025 - Safety Zones; America's Cup World Series, East Passage, Narragansett Bay, RI

Science.gov (United States)

2012-02-10

...-AA00 Safety Zones; America's Cup World Series, East Passage, Narragansett Bay, RI AGENCY: Coast Guard... the America's Cup World Series sailing vessel racing event. This safety zone is intended to safeguard...'s Cup-class races on the waters of the East Passage, Narragansett Bay, Rhode Island. Vessels will be...

The future plan for the applications of RI produced in the proton-induced spallation-reaction

Energy Technology Data Exchange (ETDEWEB)

Ikezoe, Hiroshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1997-07-01

A plan of research facilities (transmutations of minor actinides and neutron scattering for material and life sciences) has been proposed in JAERI. This plan is based on a proton lineac with an energy of 1.5 GeV and a beam current of several mA. Among these facilities, we are planning to accelerate neutron-rich radioactive nuclei (RI) produced in the fission and spallation reactions of thorium or uranium bombarded by the intense high energy proton beams. The RI produced in an ion source are separated by a high resolution isotope separator and their charge states are changed to be negative to inject into the existing tandem-booster accelerator. Main purpose of this plan is to study the nuclear and chemical properties of neutron rich transactinium elements not yet synthesized and the nuclear structures of neutron rich nuclei far from the nuclear stability line. (author)

Variabilidade da frequência cardíaca em neonatos prematuros e de termo Variabilidad de la frecuencia cardíaca en neonatos prematuros y de término Heart rate variability in preterm and term neonates

Directory of Open Access Journals (Sweden)

Fabio Augusto Selig

2011-06-01

Full Text Available FUNDAMENTO: Várias publicações têm demonstrado a importância do sistema nervoso autônomo por meio dos componentes simpático e parassimpático na gerência da interação entre as diferentes partes do organismo humano. Esses estudos aplicaram técnicas lineares e não lineares (Teoria do Caos de avaliação em diferentes situações, doenças e faixas etárias, tendo como ferramenta a variabilidade da frequência cardíaca (VFC. OBJETIVO: Aplicar os conhecimentos das dinâmicas linear e não linear na avaliação de neonatos prematuros (NPT, analisando sua VFC e comparando com neonatos de termo (NT saudáveis. MÉTODOS: Quarenta e oito neonatos prematuros com diferentes idades gestacionais tiveram seus batimentos cardíacos captados com auxílio do equipamento Polar Advanced S810i e sua VFC obtida pelo registro dos intervalos RR. A VFC foi analisada nos domínios do tempo (SDNN, RMSSD, SD1/SD2, da frequência (VLF, LF, HF e a relação LF/HF e do caos (TAU e sua normalização [TAU(n], Expoente de Lyapunov e Entropia. Os NPT foram comparados com um grupo de 78 NT saudáveis e sem intercorrências perinatais com auxílio do teste não paramétrico de Kruskal-Wallis. RESULTADOS: Detectou-se diferença estatisticamente significante entre os grupos para todas as variáveis estudadas, tanto no domínio do tempo como nos da frequência e do caos. CONCLUSÃO: Neonatos prematuros exibem comportamento menos complexo da variabilidade da frequência cardíaca que neonatos de termo, fato comprovado nos domínios do tempo, da frequência e do caos. O estudo da variabilidade cardíaca nesse grupo pode ser considerado uma ferramenta a mais na avaliação da maturação autonômica e, consequentemente, da progressão para eutrofia.FUNDAMENTO: Varias publicaciones han demostrado la importancia del sistema nervioso autónomo por medio de los componentes simpático y parasimpático en el manejo de la interacción entre las diferentes partes del organismo

Novel method for the production of spin-aligned RI beams in projectile fragmentation reaction with the dispersion matching technique

Energy Technology Data Exchange (ETDEWEB)

Ichikawa, Y., E-mail: yuichikawa@phys.titech.ac.jp [Tokyo Institute of Technology, Department of Physics (Japan); Ueno, H. [RIKEN Nishina Center (Japan); Ishii, Y. [Tokyo Institute of Technology, Department of Physics (Japan); Furukawa, T. [Tokyo Metropolitan University, Department of Physics (Japan); Yoshimi, A. [Okayama University, Research Core for Extreme Quantum World (Japan); Kameda, D.; Watanabe, H.; Aoi, N. [RIKEN Nishina Center (Japan); Asahi, K. [Tokyo Institute of Technology, Department of Physics (Japan); Balabanski, D. L. [Bulgarian Academy of Sciences, Institute for Nuclear Research and Nuclear Energy (Bulgaria); Chevrier, R.; Daugas, J. M. [CEA, DAM, DIF (France); Fukuda, N. [RIKEN Nishina Center (Japan); Georgiev, G. [CSNSM, IN2P3-CNRS, Universite Paris-sud (France); Hayashi, H.; Iijima, H. [Tokyo Institute of Technology, Department of Physics (Japan); Inabe, N. [RIKEN Nishina Center (Japan); Inoue, T. [Tokyo Institute of Technology, Department of Physics (Japan); Ishihara, M.; Kubo, T. [RIKEN Nishina Center (Japan); and others

2013-05-15

A novel method to produce spin-aligned rare-isotope (RI) beam has been developed, that is the two-step projectile fragmentation method with a technique of dispersion matching. The present method was verified in an experiment at the RIKEN RIBF, where an RI beam of {sup 32}Al with spin alignment of 8(1) % was successfully produced from a primary beam of {sup 48}Ca, with {sup 33}Al as an intermediate nucleus. Figure of merit of the present method was found to be improved by a factor larger than 50 compared with a conventional method employing single-step projectile fragmentation.

Diferencias de género en el tratamiento de la falla cardíaca

Directory of Open Access Journals (Sweden)

Clara Saldarriaga

2014-02-01

Full Text Available INTRODUCCIÓN: la falla cardíaca representa un problema creciente de salud con una alta prevalencia en el sexo femenino; sin embargo, no se han reportado estudios en población de mujeres latinoamericanas que permitan identificar si existen diferencias de género tanto en la presentación clínica como en el tratamiento de esta patología. OBJETIVO: evaluar si existen diferencias tanto en las características clínicas y epidemiológicas como en el manejo farmacológico en función del género, en una serie de pacientes con falla cardíaca atendidos en un centro de referencia cardiovascular en Colombia. METODOLOGÍA: estudio observacional, descriptivo, que evaluó a todos los pacientes hospitalizados por síndrome de falla cardiaca como diagnóstico principal durante julio de 2009 y julio de 2010 en un centro de referencia cardiovascular colombiano. RESULTADOS: se incluyeron 204 pacientes, 36,7% de sexo femenino, cuya edad promedio fue mayor en las mujeres; la fracción de eyección promedio fue similar. Las mujeres tenían falla renal con mayor frecuencia. Se encontró menor uso de betabloqueadores, así como de implante de cardiodesfibrilador. CONCLUSIÓN: para la población estudiada se encontró que existen diferencias entre ambos sexos tanto en las variables demográficas como clínicas. A pesar de presentar mayores comorbilidades, las mujeres con falla cardiaca reciben con menor frecuencia terapias como los betabloqueadores y el cardiodesfibrilador implantable que han demostrado disminuir la mortalidad. Es necesario ampliar el conocimiento de las diferencias de género mediante la creación de un registro multicéntrico latinoamericano que permita incidir en la toma de decisiones clínicas propias para la región.

Jüri Pihl usub, et sotsid suudavad Tallinna juhtimist muuta / Urmas Seaver ; kommenteerinud Remo Holsmer ja Indrek Raudne

Index Scriptorium Estoniae

Seaver, Urmas, 1973-

2009-01-01

Sotsiaaldemokraatide juht Jüri Pihl ja Keskerakonna liider Edgar Savisaar allkirjastasid Tallinna juhtimise koalitsioonileppe. Vt. samas: Mõned olulisemad lubadused koalitsioonileppest Tallinna juhtimiseks 2009-2013

190. Extubación en el Quirófano Como Rutina Tras Cirugía Cardíaca: 500 Casos Consecutivos

Directory of Open Access Journals (Sweden)

A. Ysasi

2012-04-01

Conclusiones: la extubación en el quirófano de forma rutinaria en pacientes sometidos a cirugía cardíaca es viable y segura. La necesidad de reintubación o reingreso en UCI es baja. Contribuye a la recuperación precoz del paciente y disminuye los tiempos de estancia y consumo de recursos hospitalarios.

Riigikohus arutleb autode üle / Ranno Tingas, Lemmi Kann ; kommenteerinud Jüri Allikalt

Index Scriptorium Estoniae

Tingas, Ranno, 1976-

2009-01-01

Riigikohtu lahenditest 3-3-1-93-08, 3-3-1-44-00, Tallinna Ringkonnakohtu lahendist 2-3-143/2002 sõiduautode erisoodustuse küsimuses. Kommenteerib Maksukonsultandi UÜ jurist, Eesti Maksumaksjate Liidu (EML) juhatuse liige Jüri Allikalt. Lisa: Maksuamet: sõidupäevikud ei kao kuhugi / Lemmi Kann (ÄP Online, 05.03.2009) ; MTA pressiteade ; EML teabenõue ; MTA vastus

Türi viin : aasta jagu pohmellita võidujoovastust / Cathryne Davis ; interv. Neeme Raud

Index Scriptorium Estoniae

Davis, Cathryne

2003-01-01

Ameerika Ühendriikides müüdavatest Eesti viinadest on kõige suurema edu saavutanud Türi vodka. New-Yorgi suhtekorraldusfirma Deussen Global Comunications'i esindaja Cathryne Davis näeb müügiedu põhjustena viina kõrget kvaliteeti, turundusalast koostööd rahvusvaheliselt tuntud Bacardi'ga, eliidile suunatud sponsorlust, ulatuslikku müügivõrku ja edukat reklaamikampaaniat

Validação da versão brasileira do questionário de ansiedade cardíaca

Directory of Open Access Journals (Sweden)

Aline Sardinha

2013-12-01

Full Text Available FUNDAMENTOS: A ansiedade cardíaca (AC é o medo de sensações cardíacas, caracterizado por sintomas recorrentes de ansiedade em pacientes com ou sem doença cardiovascular. O Questionário de Ansiedade Cardíaca (QAC é uma ferramenta para avaliar a AC, já adaptado, mas não validado em português. OBJETIVO: Este trabalho apresenta as três fases dos estudos de validação do QAC brasileiro. MÉTODOS: Foram recrutados 98 pacientes com doença arterial coronária, a fim de extrair a estrutura fatorial e avaliar a confiabilidade do QAC (fase 1. O objetivo da fase 2 foi explorar a validade convergente e divergente. Cinquenta e seis pacientes completaram o QAC, juntamente com o Escala de sensações corporais (ESC e o Versão brasileira do Social Phobia Inventory (SPIN. Para determinar a validade discriminante (fase 3, comparamos os escores do QAC de dois subgrupos formados por pacientes da fase 1 (n = 98, de acordo com os diagnósticos de transtorno do pânico e agorafobia obtidos com o MINI - Mini International Neuropsychiatric Interview (Mini Entrevista Neuropsiquiátrica Internacional. RESULTADOS: A solução de dois fatores foi a mais interpretável (46,4% da variância. As subescalas foram denominadas de "Medo e Hipervigilância" (n = 9; alfa = 0,88 e "Evitação" (n = 5; alfa = 0,82. Foi encontrada correlação significativa do fator 1 com o escore total do ESC (p < 0,01, mas não com o fator 2. Os fatores do SPIN apresentaram correlações significativas com as subescalas do QAC (p < 0,01. Na fase 3, os escores dos pacientes "Cardíacos com pânico" foram significativamente maiores no fator 1 do QAC (t = -3,42; p < 0,01, IC = -1,02 a -0,27, e maiores, mas não significativamente diferentes, no fator 2 (t = -1,98; p = 0,51, IC = -0.87 a 0,00. CONCLUSÕES: Os presentes resultados fornecem uma versão final brasileira validada do QAC adequada aos contextos clínicos e de pesquisa.

Avances en el conocimiento de la prehabilitación y presentación del proyecto promoción de la ambulación precoz en pacientes de cirugía no cardíaca (PAMP

Directory of Open Access Journals (Sweden)

Olga Lucía Cortés

2016-11-01

Full Text Available Introducción: La prehabilitación es un programa multidisciplinario que combina un conjunto de intervenciones (caminata, ejercicios aeróbicos, entrenamiento de los músculos inspiratorios, educación sobre nutrición y manejo psicológico orientadas hacia el mejoramiento de la capacidad funcional de los pacientes antes de asumir cualquier tipo de cirugía. Su propósito es el de preparar físicamente a los pacientes que van a cirugía (especialmente población adulta y adulta mayor y favorecer una rehabilitación rápida, la reducción de las complicaciones en el post operatorio, y una preparación adecuada para el egreso hospitalario. A pesar del conocimiento de la importancia de esta intervención poco se sabe sobre su beneficio en los resultados post operatorios de pacientes de cirugía no cardíaca. Objetivo: Describir la prehabilitación, los alcances de la evidencia científica en este tópico y presentar el proyecto promoción de la ambulación precoz en pacientes de cirugía no cardíaca (PAMP como un modelo de investigación en cirugía no cardíaca y prehabilitacion. Metodología: Se realizó una revisión no sistemática de la literatura de los fundamentos de la prehabilitación, sus orígenes, tipos de intervenciones, importancia y su eficacia en la reducción de eventos en el post operatorio de pacientes de cirugía no cardíaca. Adicionalmente se llevó a cabo una revisión de la literatura que incluyó revisiones sistemáticas y metaanálisis de ensayos clínicos sobre intervenciones evaluadas sobre prehabilitación de cirugía no cardíaca. Finalmente, se describió el alcance del proyecto PAMP en todas sus fases y su progreso hacia la implementación de un ensayo clínico de prehabilitación en Colombia mediante el estudio PAMP fase II. Conclusiones: Se requiere implementar estrategias multidisciplinarias innovadoras que promuevan mejores resultados en el post operatorio de pacientes sometidos a cirugía no cardíaca. [Cort

Efeito do transplante renal na morfologia e função cardíaca

OpenAIRE

Souza,Francival Leite de; Monteiro Junior,Francisco das Chagas; Salgado Filho,Natalino

2012-01-01

O envolvimento cardíaco é muito frequente nos portadores de doença renal crônica em diálise. O transplante renal resulta em redução da morbidade e mortalidade em relação aos pacientes em diálise. O objetivo desta revisão foi abordar o efeito do transplante renal na estrutura e função cardíaca avaliada pela ecodopplercardiografia. Desde a década de 1980, os estudos já demonstravam tendência à melhora nos parâmetros cardíacos após o transplante renal. Com a melhora dos métodos de imagens ao eco...

A heavy ion linac complex for RI beams

International Nuclear Information System (INIS)

Arai, Shigeaki

1995-01-01

A heavy ion linac complex for RI-beams has been under construction since fiscal year 1992 at INS. The linac complex comprises following accelerating structures: a 25.5-MHz split coaxial RFQ (SCRFQ), a 51-MHz interdigital-H (IH) linac, and a 25.5-MHz rebuncher cavity. The SCRFQ with modulated vanes accelerates ions with a charge-to-mass ratio (q/A) greater than 1/30 from 2 to 170 keV/u. The IH linac comprises four cavities and three magnetic quadrupole triplets placed between cavities, accelerates ions with q/A≥1/10, and varies the output energy continuously in the range 0.17 ∼1.05 MeV/u. The rebuncher cavity with six accelerating gaps is a double coaxial λ/4 resonator, and the total accelerating voltage is 200 kV. (author)

Experience of Ko-Ri Unit 1 water chemistry

International Nuclear Information System (INIS)

Tae Il Lee

1983-01-01

The main focus is placed on operational experience in secondary system water chemistry (especially the steam generator) of the Ko-Ri nuclear power plant Unit 1, Republic of Korea, but primary side chemistry is also discussed. The major concern of secondary water chemistry in a PWR is that the condition of the steam generator be well maintained. Full flow deep bed condensate polishers have recently been installed and operation started in July 1982. Boric acid treatment of the steam generator was stopped and only the all volatile treatment method was used thereafter. A review of steam generator integrity, the chemistry control programme, secondary water quality, etc. is considered to be of great value regarding the operation of Unit 1 and future units now under startup testing or construction in the Republic of Korea. (author)

Development of efficient system for collection-analysis-application of information using system for technology and information in field of RI-biomics

International Nuclear Information System (INIS)

Jang, Sol Ah; Kim, Joo Yeon; Park, Tai Jin

2015-01-01

RI-Biomics is the new radiation fusion technology of which, such as the characteristics of radioisotope, is applied to the biomics. In order to sharing and overall analysis of data between the institutions through total management of information in the field of RI-Biomics, RI-Biomics Information portal ‘RIBio-Info’ was constructed by KARA (Korean Association for Radiation Application) in February 2015. For systematic operation of this ‘RIBio-Info’ system, it is required to develop system of collection-analysis-application of information. So, in this paper, we summarized development of document forms at each processes of collection-analysis-application of information and systematization of collection methods of information, establishment of characteristically analysis methods of reports such as issue paper, policy report, global market report and watch report. Therefore, these are expected to improving the practical applicability in this field through the vitalization of technology development of users by achieving the circular structure of collection analysis-application of information

Development of efficient system for collection-analysis-application of information using system for technology and information in field of RI-biomics

Energy Technology Data Exchange (ETDEWEB)

Jang, Sol Ah; Kim, Joo Yeon; Park, Tai Jin [Korean Association for Radiation Application, Seoul (Korea, Republic of)

2015-08-15

RI-Biomics is the new radiation fusion technology of which, such as the characteristics of radioisotope, is applied to the biomics. In order to sharing and overall analysis of data between the institutions through total management of information in the field of RI-Biomics, RI-Biomics Information portal ‘RIBio-Info’ was constructed by KARA (Korean Association for Radiation Application) in February 2015. For systematic operation of this ‘RIBio-Info’ system, it is required to develop system of collection-analysis-application of information. So, in this paper, we summarized development of document forms at each processes of collection-analysis-application of information and systematization of collection methods of information, establishment of characteristically analysis methods of reports such as issue paper, policy report, global market report and watch report. Therefore, these are expected to improving the practical applicability in this field through the vitalization of technology development of users by achieving the circular structure of collection analysis-application of information.

Jüri Kasel on väljas kaks suurt näitust : ...

Index Scriptorium Estoniae

2005-01-01

Kuni 6. I 2006 saab Belgias Liege'i kaasaegse kunsti keskuses vaadata Jüri Kase suuri maale, paarisadat joonistust ning objekti ja kuni 12. XII Inglismaal Oxfordi Jacqueline du Pre muusikahoones maale. Liege'i näitusel on väljas ka Jaanus Miku tehtud video "Pinta pilte". 22.-26. XI Eesti kultuuripäevadel Oxfordis esines Weekend Guitar Trio, Kristiina Ehin luges luulet, näidati Priit Tenderi ja Ülo Pikkovi animafilme

Intrinsic vulnerability assessment of the aquifer in the Rižana spring chatcment by method SINTACS

Directory of Open Access Journals (Sweden)

2002-12-01

Full Text Available In this paper is presented intrinsic vulnerability assessment of the aquifer in the Rižana spring chatcment by the method SINTACS. It is parametric method that takes into consideration seven parameters (depth to ground water, effective infiltration action, unsaturatedzone attenuation capacity, soil/overburden attenuation capacity, hydrogeological characteristics of the aquifer, hydraulic conductivity range of aquifer, hydrologic role of the topographic slope. Parameters are presented in grid information layers that wereelaborated on the basis of interpretation and GIS processing of geological, hydrogeological,speleological, topographical, meteorological and pedological data. According to the parametersimportance for vulnerability assessment, a multiplier (importance weight was assigned to each parameter. Final map of vulnerability is a result of overlaying (summing of weighted information layers (parameters and shows the catchment area of the Rižanaspring subdivided into six vulnerability classes.

Turvalist kooliaastat - koolis, tänaval ja internetis / Jüri Pihl

Index Scriptorium Estoniae

Pihl, Jüri, 1954-

2008-01-01

Ilmunud ka: Molodjozh Estonii 1. sept. lk. 4-5, Sakala 2. sept., lk. 2, Virumaa Teataja 2. sept., lk. 11, Oma Saar 2. sept., lk. 5, Tartu Postimees 2. sept., lk. 2, Hiiu Leht 2. sept., lk. 2, Pärnu Postimees 2. sept., lk. 15, Koit 2. sept. lk. 6, Sõnumitooja 3. sept. lk. 2, Vooremaa 4. sept. lk. 2. Siseminister Jüri Pihl esitab kolm suuremat probleemi, mis vähendavad turvalisust koolis ja kooliteel: ohud liikluses, kasvav meelemürkide tarvitamine ning koolivägivald

Higher Loop Corrections to the Infrared Evolution of Fermionic Gauge Theories in the RI' Scheme

DEFF Research Database (Denmark)

Ryttov, Thomas

2014-01-01

We study the evolution of the gauge coupling and the anomalous dimension of the mass towards an infrared fixed point for non-supersymmetric gauge theories in the modified regularization invariant, RI', scheme. This is done at the three loop level where all the renormalization group functions have...

Synthesis, crystal structure, and magnetism of A{sub 2}Co{sub 12}As{sub 7} (A=Ca, Y, Ce–Yb)

Energy Technology Data Exchange (ETDEWEB)

Tan, Xiaoyan [Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306 (United States); Ovidiu Garlea, V. [Quantum Condensed Matter Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Chai, Ping [Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306 (United States); Geondzhian, Andrey Y. [National Research Nuclear University “Moscow Engineering Physics Institute”, 115409 Moscow (Russian Federation); Yaroslavtsev, Alexander A. [National Research Nuclear University “Moscow Engineering Physics Institute”, 115409 Moscow (Russian Federation); European XFEL GmbH, 22761 Hamburg (Germany); Xin, Yan [National High Magnetic Field Laboratory, Tallahassee, FL 32310 (United States); Menushenkov, Alexey P. [National Research Nuclear University “Moscow Engineering Physics Institute”, 115409 Moscow (Russian Federation); Chernikov, Roman V. [DESY Photon Science, 22603 Hamburg (Germany); Shatruk, Michael, E-mail: shatruk@chem.fsu.edu [Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306 (United States)

2016-04-15

Ternary intermetallics, A{sub 2}Co{sub 12}As{sub 7} (A=Ca, Y, Ce–Yb), have been synthesized by annealing mixtures of elements in molten Bi at 1223 K. The materials obtained crystallize in the P6{sub 3}/m variant of the Zr{sub 2}Fe{sub 12}P{sub 7} structure type. The unit cell volume shows a monotonic decrease with the increasing atomic number of the rare-earth metal, with the exception of Ce-, Eu-, and Yb-containing compounds. An examination of these outliers with X-ray absorption near edge structures (XANES) spectroscopy revealed mixed valence of Ce, Eu, and Yb, with the average oxidation states of +3.20(1), +2.47(5), and +2.91(1), respectively, at room temperature. Magnetic behavior of A{sub 2}Co{sub 12}As{sub 7} is generally characterized by ferromagnetic ordering of Co 3d moments at 100–140 K, followed by low-temperature ordering of rare-earth 4f moments. The 3d-4f magnetic coupling changes from antiferromagnetic for A=Pr–Sm to ferromagnetic for A=Ce and Eu–Yb. Polarized neutron scattering experiments were performed to support the postulated ferro- and ferrimagnetic ground states for Ce{sub 2}Co{sub 12}As{sub 7} and Nd{sub 2}Co{sub 12}As{sub 7}, respectively. - Graphical abstract: Title arsenides were synthesized by Bi‐flux method. They exhibit mixed valence for A = Ce, Eu, Yb, ferrimagnetism for A = Ca, Y, Pr–Sm, and ferromagnetism for A = Eu–Tm. - Highlights: • A2Co12As7 (A=Ca, Y, Ce–Yb) were synthesized in Bi flux. • Ce, Eu, Yb exhibit mixed valence in the corresponding structures. • The character of 3d‐4f magnetic coupling changes at the half‐filled f shell. • Materials behave as ferrimagnets for A=Ca, Y, Pr–Sm and as ferromagnets for A=Eu–Yb.

Direct evidence that FK506 inhibition of FcepsilonRI-mediated exocytosis from RBL mast cells involves calcineurin.

Science.gov (United States)

Hultsch, T; Brand, P; Lohmann, S; Saloga, J; Kincaid, R L; Knop, J

1998-05-01

FcepsilonRI-mediated exocytosis of preformed mediators from mast cells and basophils (e.g. histamine, serotonin, beta-hexosaminidase) is sensitive to the immunosuppressants cyclosporin A and FK506 (IC50 200 and 4 nM, respectively) but not rapamycin. The mechanism of inhibition does not appear to involve tyrosine phosphorylation, hydrolysis of inositol phosphates or calcium flux. Here we report experiments using a molecular approach to assess the role of calcineurin, a serine/threonine phosphatase thought to be the primary pharmacological target of these drugs. Calcineurin's activity requires association of its catalytic (A) subunit with an intrinsic regulatory (B) subunit. We hypothesized that calcineurin-sensitive signalling events should be affected by the depletion of calcineurin B subunits, thereby reducing the number of active A:B complexes. We therefore transfected rat basophilic leukemia (RBL) cells with an inhibitory (dominant negative) form of the calcineurin A subunit, which binds the calcineurin B subunit with high affinity but does not possess catalytic activity (B subunit knock-out, BKO). In these transfected cells, the dose-response curve for the inhibition of FcepsilonRI-mediated exocytosis by FK506 was shifted to the left, indicating an increased drug sensitivity of BKO-transfected cells. We conclude that FK506 inhibition of FcepsilonRI-mediated exocytosis in mast cells specifically targets calcineurin activity.

Racionalidade e métodos: estudo BREATHE - I registro brasileiro de insuficiência cardíaca

Directory of Open Access Journals (Sweden)

2013-05-01

Full Text Available FUNDAMENTO: Diversos registros locais buscam de forma isolada retratar características clínicas de pacientes internados com Insuficiência Cardíaca (IC em hospitais e comunidades brasileiras. De forma geral, a análise desses dados sugere que existam diferenças importantes na etiologia, nos fatores de descompensação, no tratamento e no prognóstico de pacientes com IC nas diferentes regiões brasileiras. OBJETIVOS: Avaliar as características demográficas, clínicas, prognósticas de 1.200 pacientes admitidos com diagnóstico clínico de insuficiência cardíaca descompensada em um grupo de 60 hospitais representativos das diferentes regiões brasileiras. MÉTODOS: Estudo observacional transversal (registro com seguimento longitudinal de doze meses (visitas de admissão, alta hospitalar, três meses, seis meses e doze meses após inclusão, em que pacientes admitidos em hospitais da rede pública e privada com quadro clínico primariamente de IC definida serão estudados. RESULTADOS: Os resultados serão apresentados logo após o término da coleta, avaliação da qualidade e análise estatística dos dados. CONCLUSÕES: A análise dos resultados deste registro multicêntrico permitirá um planejamento mais adequado do aporte de recursos financeiros, pessoais e tecnológicos para a área da saúde, bem como o planejamento de medidas preventivas mais eficazes na IC descompensada.

PENGARUH TEKANAN WAKTU, RISIKO AUDIT, TINDAKAN SUPERVISI, DAN MATERIALITAS TERHADAP PENGHENTIAN PREMATUR ATAS PROSEDUR AUDIT (Studi Empiris pada BPK RI Perwakilan Provinsi Sulawesi Selatan)

OpenAIRE

IBRAHIM, KHAIRURRIJAL

2015-01-01

2015 ABSTRAK Pengaruh Tekanan Waktu, Risiko Audit, Tindakan Supervisi dan Materialitas terhadap Penghentian Prematur Atas Prosedur Audit (Studi Empiris pada BPK RI Perwakilan Provinsi Sulawesi Selatan) Khairurrijal Ibrahim Mushar Mustafa Asri Usman Penelitian ini bertujuan untuk mengetahui apakah tekanan waktu, risiko audit, tindakan supervisi, dan materilaitas berpengaruh terhadap penghentian premature atas prosedur audit yang dilakukan oleh auditor BPK RI Perwa...

The diagnosis of cerebrospinal fluid hypovolemia. The comparison between CT myelography and RI cisternography

International Nuclear Information System (INIS)

Watanabe, Keisuke; Hashizume, Keiji; Inoue, Satoki; Fujiwara, Aki; Furuya, Hitoshi

2008-01-01

The comparison in the title is performed in cases with suspicious hypovolemia of cerebrospinal fluid (CSF) and its leak at the lumbar region is also examined in whiplash injury. Subjects are 25 cases (M 14/F 11, av. age 36.9 y) with traffic (13 cases), whiplash (4) and null (8) injuries. CT myelography (CTM) is conducted by injection of iotrolan through the lumbar puncturing needle to get 700 images of the whole spine of 1 mm slice thickness, which after animated, are observed visually. RI cisternography (RIC) is done immediately, 2 and 24 hr after injection of 10 MBq of diethylenetriamine pentaacetic acid (DTPA)-In through the puncturing needle. In 15 cases exhibiting positive RIC findings, CTM gives a positive leak at cervical and thoracic regions only in 2 cases and a false positive in other 13. In contrast, RIC fails to detect 2 cases of 4 with a leak at cervical and thoracic regions. Thus RIC is less reliable, and often observable RI accumulation at the lumbar area in RIC is not always a leak. (R.T.)

Clinical efficacy of omalizumab in chronic spontaneous urticaria is associated with a reduction of FcεRI-positive cells in the skin.

Science.gov (United States)

Metz, Martin; Staubach, Petra; Bauer, Andrea; Brehler, Randolf; Gericke, Janine; Kangas, Michael; Ashton-Chess, Joanna; Jarvis, Philip; Georgiou, Panayiotis; Canvin, Janice; Hillenbrand, Rainer; Erpenbeck, Veit J; Maurer, Marcus

2017-01-01

Background. Treatment with omalizumab, a humanized recombinant monoclonal anti-IgE antibody, results in clinical efficacy in patients with Chronic Spontaneous Urticaria (CSU). The mechanism of action of omalizumab in CSU has not been elucidated in detail. Objectives. To determine the effects of omalizumab on levels of high affinity IgE receptor-positive (FcεRI + ) and IgE-positive (IgE + ) dermal cells and blood basophils. Treatment efficacy and safety were also assessed. Study design. In a double-blind study, CSU patients aged 18‑75 years were randomized to receive 300 mg omalizumab (n=20) or placebo (n=10) subcutaneously every 4 weeks for 12 weeks. Changes in disease activity were assessed by use of the weekly Urticaria Activity Score (UAS7). Circulating IgE levels, basophil numbers and levels of expression of FcεRI + and IgE + cells in the skin and in blood basophils were determined. Results. Patients receiving omalizumab showed a significantly greater decrease in UAS7 compared with patients receiving placebo. At Week 12 the mean difference in UAS7 between treatment groups was -14.82 (p=0.0027), consistent with previous studies. Total IgE levels in serum were increased after omalizumab treatment and remained elevated up to Week 12. Free IgE levels decreased after omalizumab treatment. Mean levels of FcεRI + skin cells in patients treated with omalizumab 300 mg were decreased at Week 12 compared with baseline in the dermis of both non-lesional and lesional skin, reaching levels comparable with those seen in healthy volunteers (HVs). There were no statistically significant changes in mean FcɛRI + cell levels in the placebo group. Similar results were seen for changes in IgE + cells, although the changes were not statistically significant. The level of peripheral blood basophils increased immediately after treatment start and returned to Baseline values after the follow-up period. The levels of FcεRI and IgE expression on peripheral blood basophils were

Miks on tühjad tähistajad poliitikas olulised? / Ernesto Laclau ; tõlk. Jüri Lipping

Index Scriptorium Estoniae

Laclau, Ernesto

2002-01-01

Filosoofiline arutelu "tühjade tähistajate" ühiskondlikust tootmisest. Hegemoonia. Hegemoonia ja demokraatia. Artikli lõpus Jüri Lippingu ülevaade Ernesto Laclau ja Chantal Mouffe teosest "Hegemony and Socialist Strategy"

Matriz binária RiC: classificação filogenética da informação arquivística

OpenAIRE

Macedo, Laureano Secundino Ascensão de

2017-01-01

Ascensão de Macedo, L. S., 2017, "Matriz binária RiC: classificação filogenética da informação arquivística", doi:10.7910/DVN/ERE8HL, Harvard Dataverse, V1 Constam três folhas: 1 - matriz binária com propriedades RiC e taxa (tipologias documentais); 2 - matriz binária simples (processamento em DendroUPGMA); 3 - 3 outputs de DendroUPGMA: matriz bicaudal de similaridade, de distâncias e formato Newick. (2017-01-18)

Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes.

Science.gov (United States)

Li, Xian; Lee, Youn Ju; Jin, Fansi; Park, Young Na; Deng, Yifeng; Kang, Youra; Yang, Ju Hye; Chang, Jae-Hoon; Kim, Dong-Young; Kim, Jung-Ae; Chang, Young-Chae; Ko, Hyun-Jeong; Kim, Cheorl-Ho; Murakami, Makoto; Chang, Hyeun Wook

2017-07-25

Sirt1, a key regulator of metabolism and longevity, has recently been implicated in the regulation of allergic reactions, although the underlying mechanism remains unclear. Here we show that Sirt1 negatively regulates FcεRI-stimulated mast cell activation and anaphylaxis through two mutually regulated pathways involving AMP-activated protein kinase (AMPK) and protein tyrosine phosphatase 1B (PTP1B). Mast cell-specific knockout of Sirt1 dampened AMPK-dependent suppression of FcεRI signaling, thereby augmenting mast cell activation both in vitro and in vivo. Sirt1 inhibition of FcεRI signaling also involved an alternative component, PTP1B, which attenuated the inhibitory AMPK pathway and conversely enhanced the stimulatory Syk pathway, uncovering a novel role of this phosphatase. Moreover, a Sirt1 activator resveratrol stimulated the inhibitory AMPK axis, with reciprocal suppression of the stimulatory PTP1B/Syk axis, thus potently inhibiting anaphylaxis. Overall, our results provide a molecular explanation for the beneficial role of Sirt1 in allergy and underscore a potential application of Sirt1 activators as a new class of anti-allergic agents.

Crianças e adolescentes que convivem com diabetes e doença celíaca

OpenAIRE

Brancaglioni, Bianca de Cássia Alvarez; Rodrigues, Grasiele Caroline; Damião, Elaine Buchhorn Cintra; Queiroz, Márcia Silva; Nery, Márcia

2016-01-01

RESUMO Objetivo Compreender a experiência de crianças e adolescentes que convivem com diabetes mellitus tipo 1 e doença celíaca. Método Estudo qualitativo, exploratório e descritivo. A coleta de dados ocorreu entre janeiro e setembro de 2012, com 3 crianças e 2 adolescentes, em um ambulatório de diabetes do Hospital das Clinicas da FMUSP ou na residência dos participantes na cidade de São Paulo, por meio de entrevistas semiestruturadas. Utilizou-se a Análise de Conteúdo como método de tra...

Molecular cloning and restriction analysis of EcoRI-fragments of Vicia faba rDNA

International Nuclear Information System (INIS)

Yakura, Kimitaka; Tanifuji, Shigeyuki.

1983-01-01

EcoRI-fragments of Vicia faba rDNA were cloned in plasmid pBR325. Southern blot hybridization of BamHI-digests of these cloned plasmids and Vicia genomic DNA led to the determination of relative positions of BamHI sites in the rDNA and the physical map that had been tentatively made is corrected. (author)

Link Between RI-ISI and Inspection Qualification: Relationship between Defect Detection Rate and Margin of Detection

International Nuclear Information System (INIS)

Shepherd, Barrie; Goujon, Sophie; Whittle, John

2007-01-01

Quantitative risk-informed in-service inspection (RI-ISI) requires a quantitative measurement of inspection effectiveness if the risk change associated with an inspection is to be determined. Knowing the probability of detection (POD) as a function of defect depth (through wall dimension) would provide ideal information. However the main in-service inspection method for nuclear plant is ultrasonics, for which defect detection capability depends on a wide variety of parameters besides defect depth, such as defect orientation, roughness, location, shape etc. In recognition of this the European approach to inspection qualification is generally based on some combination of technical justification, and practical trials on a relatively limited number of defects. This inspection qualification process involves demonstrating that defects of concern will generate responses in excess of the specified recording level or noise, depending on the inspection. It is not currently designed to quantify the probability with which defects will be detected. The work described in this report has been performed in order to help address the problem of how the information generated during inspection qualification can be used as an input for RI-ISI. The approach adopted has been to recognise that as the defect response increases above the recording or noise level, the probability of detecting defects is likely to increase. The work therefore involved an investigation of the relationship between POD (strictly speaking defect detection rate) and margin of detection. It involved blind manual and automated ultrasonic trials on artificial defects in test plates designed to generate a range of signal responses. The detection rate for defects which provided signals at a particular level above noise or above a recording level was then measured. A relationship between defect detection rate and margin of detection has been established based on these trials. In addition to establishing a stronger link

Jüri Lina : "Rain Tolk pöördugu kiiremas korras psühhiaatri poole!" / Kadi Viljak

Index Scriptorium Estoniae

Viljak, Kadi

2003-01-01

Poliitikuid pilav Rain Tolki ja Ken Saani pseudodokumentaalfilm "Welcome To Estonia" : režissöör Andres Maimik. Filmis oma seisukohtadega esinev Jüri Lina on nördinud enda alatu ärakasutamise üle

Endurance test on IR rig for RI production

International Nuclear Information System (INIS)

Chung, Heung June; Youn, Y. J.; Han, H. S.; Hong, S. B.; Cho, Y. G.; Ryu, J. S.

2000-12-01

This report presents the pressure drop, vibration and endurance test results for IR rig for RI production which were desigened and fabricated by KAERI. From the pressure drop test results, it is noted that the flow rate through the IR rig corresponding to the pressure drop of 200 kPa is measured to be about 3.12 kg/sec. Vibration frequency for the IR rig ranges from 13 to 17 Hz. RMS(Root Mean Square) displacement for the IR rig is less than 30 μm, and the maximum displacement is less than 110μm. These experimental results show that the design criteria of IR rig meet the HANARO limit conditions. Endurance test results show that the appreciable fretting wear for the IR rig does not occur, however tiny trace of wear between contact points is observed

77 FR 16974 - Special Local Regulations; Ocean State Tall Ships Festival 2012, Narragansett Bay, RI

Science.gov (United States)

2012-03-23

...-AA08 Special Local Regulations; Ocean State Tall Ships Festival 2012, Narragansett Bay, RI AGENCY... Island, for the Ocean State Tall Ships Festival 2012. This action is necessary to provide for the safety..., during the Ocean State Tall Ships Festival on July 6-9, 2012. These temporary special local regulations...

Strengthening the infrastructure for RI applications in cooperation with the IAEA

Energy Technology Data Exchange (ETDEWEB)

Park, Kyung Bae; Hong, Young Don; Kim, Seung Yun; Kim, Kyoung Pyo; Lee, Jeong Kong

2000-12-01

The future direction for nuclear cooperation should be implemented with the aim of enhancing the status of Korea within the international society as well as carrying out the established national nuclear policy goal. Strategies for implementing cooperation with the IAEA were described into four separate parts; 'strategies for strengthening cooperation in general areas', 'strategies for implementing IAEA technical cooperation programs', 'strategies for implementing IAEA CRP programs' and 'Strategies for effective participation in the area of radiation and RI application'. As for strategies for implementing IAEA technical cooperation programs, i) expanding domestic personnel's entering into the IAEA ii) establishment of a liaison office for support of IAEA technical cooperation iii) expanding domestic experts entering into member of consultation group for a director-general of the IAEA and more participation in the international meetings iv) cooperation with IAEA's Seibersdorf Laboratories. For the strengthening of IAEA technical cooperation, strategies for effective implementation of technical cooperation programs such as i) strengthening role of national TC liaison officer ii) strengthening application of Model Project concept iii) Implementing End-user oriented programs iv) Establishment of measure to increase the TC implementation rate v) hosting of fellowship, scientific visitors, support for expert mission, were presented. Strategies for expanding domestic participation in the IAEA technical cooperation programs were also described for producing the benefits from implementing the IAEA technical cooperation programs. As for strategies for implementing the IAEA CRP programs, i) measures for active participation in the IAEA CRP programs and ii) measures for gradual participation in the IAEA CRP programs were separately described. To maximize the utilization of HANARO, a multi-purpose research reactor, the on

Strengthening the infrastructure for RI applications in cooperation with the IAEA

International Nuclear Information System (INIS)

Park, Kyung Bae; Hong, Young Don; Kim, Seung Yun; Kim, Kyoung Pyo; Lee, Jeong Kong

2000-12-01

The future direction for nuclear cooperation should be implemented with the aim of enhancing the status of Korea within the international society as well as carrying out the established national nuclear policy goal. Strategies for implementing cooperation with the IAEA were described into four separate parts; 'strategies for strengthening cooperation in general areas', 'strategies for implementing IAEA technical cooperation programs', 'strategies for implementing IAEA CRP programs' and 'Strategies for effective participation in the area of radiation and RI application'. As for strategies for implementing IAEA technical cooperation programs, i) expanding domestic personnel's entering into the IAEA ii) establishment of a liaison office for support of IAEA technical cooperation iii) expanding domestic experts entering into member of consultation group for a director-general of the IAEA and more participation in the international meetings iv) cooperation with IAEA's Seibersdorf Laboratories. For the strengthening of IAEA technical cooperation, strategies for effective implementation of technical cooperation programs such as i) strengthening role of national TC liaison officer ii) strengthening application of Model Project concept iii) Implementing End-user oriented programs iv) Establishment of measure to increase the TC implementation rate v) hosting of fellowship, scientific visitors, support for expert mission, were presented. Strategies for expanding domestic participation in the IAEA technical cooperation programs were also described for producing the benefits from implementing the IAEA technical cooperation programs. As for strategies for implementing the IAEA CRP programs, i) measures for active participation in the IAEA CRP programs and ii) measures for gradual participation in the IAEA CRP programs were separately described. To maximize the utilization of HANARO, a multi-purpose research reactor, the on-going development and development project are actively

Lesão neurológica em cirurgia cardíaca: aspectos fisiopatológicos Lesión neurológica en cirugía cardíaca Pathophysiology of neurological injuries during heart surgery: aspectos fisiopatológicos

Directory of Open Access Journals (Sweden)

Rólison Gustavo Bravo Lelis

2004-08-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: Em virtude de as lesões neurológicas ocuparem um papel importante no contexto das complicações pós-operatórias, quando comparadas às demais, o presente estudo procurou discutir os principais fatores envolvidos na lesão neurológica peri-operatória em cirurgia cardíaca, as intervenções que buscam diminuir a incidência de lesões neurológicas, enfocando de maneira simples, e a provável gênese genética em tais lesões encefálicas. CONTEÚDO: Este trabalho contém a revisão de artigos que enfocam a fisiopatologia das lesões neurológicas relacionadas a procedimentos cardíacos, sua possível origem genética, bem como uma proposta para sua prevenção. CONCLUSÕES: Muito tem se falado das disfunções cognitivas de pacientes após cirurgia cardíaca, como a revascularização do miocárdio que é motivo do aumento da morbimortalidade observada atualmente e fator de maior tempo de hospitalização. É fato que já houve grandes avanços nessa área a fim de diminuir esses índices, prevendo-se ainda outros que visam a profilaxia de lesões neurológicas.JUSTIFICATIVA Y OBJETIVOS: En virtud de las lesiones neurológicas que ocupan un papel importante en el contexto de las complicaciones pós-operatorias, cuando comparadas a las demás, el presente estudio tentó discutir los principales factores envueltos en la lesión neurológica peri-operatoria en cirugía cardíaca, las intervenciones que buscan disminuir la incidencia de lesiones neurológicas, enfocando de manera simple, y la probable génesis genética en tales lesiones cerebrales. CONTENIDO: Este trabajo contiene la revisión de artículos que enfocan la fisiopatología de las lesiones neurológicas relacionadas a procedimientos cardíacos, su posible origen genético, bien como una propuesta para su prevención. CONCLUSIONES: Mucho se habló de las disfunciones cognitivas de pacientes después de cirugía cardíaca, como la revascularización del

Contribution of IL-1RI Signaling to Protection against Cryptococcus neoformans 52D in a Mouse Model of Infection

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Mitra Shourian

2018-01-01

Full Text Available Interleukin-1 alpha (IL-1α and interleukin-1 beta (IL-1β are pro-inflammatory cytokines that are induced after Cryptococcus neoformans infection and activate the interleukin-1 receptor type I (IL-1RI. To establish the role of IL-1RI signaling in protection against cryptococcal infection, we analyzed wild-type (WT and IL-1RI-deficient (IL-1RI−/− mice on the BALB/c background. IL-1RI−/− mice had significantly reduced survival compared to WT mice after intratracheal challenge with C. neoformans 52D. Microbiological analysis showed a significant increase in the lung and brain fungal burden of IL-1RI−/− compared to WT mice beginning at weeks 1 and 4 postinfection, respectively. Histopathology showed that IL-1RI−/− mice exhibit greater airway epithelial mucus secretion and prominent eosinophilic crystals that were absent in WT mice. Susceptibility of IL-1RI−/− mice was associated with significant induction of a Th2-biased immune response characterized by pulmonary eosinophilia, M2 macrophage polarization, and recruitment of CD4+ IL-13+ T cells. Expression of pro-inflammatory [IL-1α, IL-1β, TNFα, and monocyte chemoattractant protein 1 (MCP-1], Th1-associated (IFNγ, and Th17-associated (IL-17A cytokines was significantly reduced in IL-1RI−/− lungs compared to WT. WT mice also had higher expression of KC/CXCL1 and sustained neutrophil recruitment to the lung; however, antibody-mediated depletion of these cells showed that they were dispensable for lung fungal clearance. In conclusion, our data indicate that IL-1RI signaling is required to activate a complex series of innate and adaptive immune responses that collectively enhance host defense and survival after C. neoformans 52D infection in BALB/c mice.

Euroopa firmad on asunud oma äri ümber korraldama / Ralph Atkins, Peggy Hollinger

Index Scriptorium Estoniae

Atkins, Ralph

2004-01-01

Euroopa Liidu juhtide sõnul liigutakse aeglaselt 2000. aastal Lissaboni tippkohtumisel seatud sihtidele viia Euroopa majandus konkurentsivõimelt esikohale maailmas. Euroopa ettevõtted on asunud äri ümberstruktureerima eesmärgiga kärpida kulusid ja leida firmade konkurentsieeliseid. Lisad: Muundumine nagu õpikus; Ümberkorraldamise tulemused siiani teadmata; Erik Aru. Eestis on eduka restruktureerimise näiteks Baltika ja Harju Elekter

Associação entre autocuidado e reinternação hospitalar de pacientes com insuficiência cardíaca

Directory of Open Access Journals (Sweden)

Amanda Chlalup Linn

2016-06-01

Full Text Available RESUMO Objetivo: verificar associação entre o autocuidado e o número de reinternações hospitalares de pacientes com diagnóstico de insuficiência cardíaca (IC descompensada, bem como testar a aplicabilidade de dois instrumentos de avaliação de autocuidado. Estudo longitudinal, realizado em um hospital de referência cardiológica do sul do Brasil. Método: foram incluídos 82 pacientes, com idade média de 61,85±12,33 anos, 57,3% do sexo masculino. O escore médio da avaliação de autocuidado encontrado pelas escalas European Heart Failure Self-care Behavior Scale e a Escala de Autocuidado para Pacientes com Insuficiência Cardíaca foi insatisfatório. Resultados: foi verificada uma média de 2,57±1,66 reinternações hospitalares no último ano por descompensação da IC. Houve correlação entre os escores de autocuidado com número de reinternações hospitalares por IC descompensada. Escolaridade e idade mostraram-se associadas ao autocuidado dos pacientes com IC. Conclusão: ambas as escalas avaliam o autocuidado de forma relevante, sendo correlacionados os seus índices.

Evaluation of RI images of hepatic blood flow using Tc-99m PMT

Energy Technology Data Exchange (ETDEWEB)

Fujiwara, Hiromichi; Iwasaki, Naoya; Ichikawa, Kesato

1988-03-01

To evaluate the clinical significance of RI images of hepatic blood flow using Tc-99m-PMT, analysis of the RI images and estimation of hepatic blood flow were carried out in patients with various liver diseases (37 cases). After intravenous injection of Tc-99m-PMT, hepatic accumulation curve of ROI positioned at whole liver area and time activity curve of ROI positioned at celiac artery were obtained through scintillation camera images with the computer-analysed system. Hepatic blood flow coefficient (K) was calculated from the hepatic accumulation curve. Based on the differential curve calculated from the time activity curve, chronological images of arterial, portal, parenchymal and saturated parenchymal phases were obtained. Results ; 1) K was 0.50 + 0.04, 0.35 + 0.02 and 0.26 + 0.04/min in normal type, CH type and LC type respectively. These coefficients well correlated with clinical severity of hepatic diseases. 2) Perfusional phase images of the liver became poorer in accordance with progression of liver disease, while images of spleen, portal venous system and collateral channels were more clearly obtained in liver cirrhosis. This method was shown to have a potential to understanding of severity of liver disease and hepatic blood flow dynamics.

Two-dimensional echocardiographic and RI angiographic features of aneurysm of the ascending aorta in patients with annuloaortic ectasia

International Nuclear Information System (INIS)

Nakamura, Kenji; Suzuki, Shin; Satomi, Gengi

1981-01-01

The purpose of this study was to compare the diagnostic value of two-dimensional echocardiography with that of other methods in the detection and localization of aneurysm involving the ascending aorta in patients with annuloaortic ectasia. Two-dimensional echocardiography, RI angiography, CT scan and aortography were performed in 19 patients (12 patients with Marfan's syndrome, 4 with aortitis syndrome and 3 with postoperative perivalvular aneurysm). Eight of 12 patients with Marfan's syndrome had dissection in the ascending aorta which was confirmed at surgery or autopsy. The following observations were obtained. 1) Dissection of the ascending aorta was clearly demonstrated on the two-dimensional echocardiogram in 7 patients by recording the intinal tear and flap, and in these cases the short axis two-dimensional echocardiogram of the ascending aorta was more useful in identifying the site and extent of dissection. 2) In patients with postoperative perivalvular aneurysms, RI angiography proved to be a more useful and sensitive technique in differentiating a leakage into the aneurysm from clots in the aneurysm. 3) CT scanning proved to be an insensitive technique to detect dissection of the ascending aneurysm and to differentiate a leakage from clots in the perivalvular aneurysm. From these observations, we concluded that two-dimensional echocardiography and RI angiography proved to be sensitive techniques in detecting dissection of the ascending aneurysm and evaluating a postoperative aneurysm in patients with annuloaortic ectasia. (author)

Efeito da respiração diafragmática sobre a variabilidade da frequência cardíaca na doença cardíaca isquêmica com diabete Efecto de la respiración diafragmática sobre la variabilidad de la frecuencia cardiaca en la enfermedad cardiaca isquémica con diabetes Effect of diaphragmatic breathing on heart rate variability in ischemic heart disease with diabetes

OpenAIRE

Anupama Bangra Kulur; Nagaraja Haleagrahara; Prabha Adhikary; P. S. Jeganathan

2009-01-01

FUNDAMENTO: A diminuição da variabilidade da frequência cardíaca (VFC) está associada com um prognóstico desfavorável em pacientes com doença cardíaca isquêmica (DCI) e diabete. Ainda não foi provado em definitivo se a mudança no padrão respiratório pode modificar o fator de risco nesses pacientes. OBJETIVO: Avaliar o efeito da respiração diafragmática sobre a VFC em pacientes diabéticos com DCI. MÉTODOS: A população do estudo consistiu em 145 pacientes do sexo masculino selecionados ao acaso...

Kaug-Ida autoäri eripärast - sae kas või maastur pooleks / Jaanus Piirsalu

Index Scriptorium Estoniae

Piirsalu, Jaanus, 1973-

2010-01-01

2009. a. tõsteti Venemaal sisseveetavate kasutatud autode tollimakse. Nüüd saetakse Vladivostokki teel olevad kasutatud autod Jaapanis pooleks ja tuuakse üle piiri kui varuosad. Poolitatud autod keevitatakse Vladivostokis taas kokku. Kasutatud autode äri on Kaug-Idas vähenenud kümneid kordi

Eesti Vabariigi põhiseadus : kommenteeritud väljaanne / toimetuskolleegium: Eerik-Juhan Truuväli, Oliver Kask, Lasse Lehis, Heiki Lindpere, Uno Lõhmus, Ülle Madise, Kalle Merusk, Raul Narits, Vallo Olle, Jüri Põld, Heinrich Schneider

Index Scriptorium Estoniae

2002-01-01

Kommentaaride autorid ja sisu: Sissejuhatus / Raul Narits, Heinrich Schneider, Lauri Madise. [Preambul] / Heinrich Schneider. I ptk. / Kalle Merusk, Taavi Annus, Madis Ernits, Heiki Lindpere, Lauri Madise. II ptk. / Uno Lõhmus, Taavi Annus, Madis Ernits, Oliver Kask, Eerik Kergandberg, Rait Maruste, Peeter Roosma. III ptk. / Oliver Kask. IV ptk. / Jüri Põld, Lauri Madise, Aaro Mõttus. V ptk. / Eerik-Juhan Truuväli, Ülle Madise, Jüri Põld, Urmas Reinsalu. VI ptk. / Kalle Merusk, Jüri Põld. VII ptk. / Eerik-Juhan Truuväli, Jüri Põld. VIII ptk. / Lasse Lehis. IX ptk. / Heiki Lindpere, Kristi Land, Lauri Madise, Heiki Pisuke. X ptk. / Oliver Kask, Enn Markvart, Jüri Põld. XI ptk. / Heinrich Schneider. XII ptk. / Raul Narits, Aare Reenumägi, Peeter Roosma, Enn Markvart. XIII ptk. / Uno Lõhmus, Madis Ernits, Jüri Põld. XIV ptk. / Vallo Olle, Arno Almann, Ülle Madise, Jüri Liventaal. XV ptk. / Eerik-Juhan Truuväli, Aaro Mõttus. Eesti Vabariigi põhiseaduse rakendamise seadus / Raul Narits, Peeter Roosma, Oliver Kask. Märksõnastik / koost. Ülle Madise, Peep Pruks. Kasutatud õigusaktide lühendid / koost. Virgo Saarmets. Eesti Vabariigi põhiseadus 1990-2002 : bibliograafia / koost. Maia Ruttu

Fer and Fps/Fes participate in a Lyn-dependent pathway from FcepsilonRI to platelet-endothelial cell adhesion molecule 1 to limit mast cell activation.

Science.gov (United States)

Udell, Christian M; Samayawardhena, Lionel A; Kawakami, Yuko; Kawakami, Toshiaki; Craig, Andrew W B

2006-07-28

Mast cells express the high affinity IgE receptor FcepsilonRI, which upon aggregation by multivalent antigens elicits signals that cause rapid changes within the mast cell and in the surrounding tissue. We previously showed that FcepsilonRI aggregation caused a rapid increase in phosphorylation of both Fer and Fps/Fes kinases in bone marrow-derived mast cells. In this study, we report that FcepsilonRI aggregation leads to increased Fer/Fps kinase activities and that Fer phosphorylation downstream of FcepsilonRI is independent of Syk, Fyn, and Gab2 but requires Lyn. Activated Fer/Fps readily phosphorylate the C terminus of platelet-endothelial cell adhesion molecule 1 (Pecam-1) on immunoreceptor tyrosine-based inhibitory motifs (ITIMs) and a non-ITIM residue (Tyr(700)) in vitro and in transfected cells. Mast cells devoid of Fer/Fps kinase activities display a reduction in FcepsilonRI aggregation-induced tyrosine phosphorylation of Pecam-1, with no defects in recruitment of Shp1/Shp2 phosphatases observed. Lyn-deficient mast cells display a dramatic reduction in Pecam-1 phosphorylation at Tyr(685) and a complete loss of Shp2 recruitment, suggesting a role as an initiator kinase for Pecam-1. Consistent with previous studies of Pecam-1-deficient mast cells, we observe an exaggerated degranulation response in mast cells lacking Fer/Fps kinases at low antigen dosages. Thus, Lyn and Fer/Fps kinases cooperate to phosphorylate Pecam-1 and activate Shp1/Shp2 phosphatases that function in part to limit mast cell activation.

Lääs ja süntetismi väljakutsed / Jüri Talvet

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

2002-01-01

Kokkuvõte "The West and the challenge of synthetism", lk. 1089-1090. Kriitiliselt Lääne kultuuriuuringute diskursustest: eksistentsialism, strukturalism, psühhoanalüüs, poststrukturalism. Essee aluseks on hispaaniakeelne plenaarettekanne rahvusvahelisel kongressil Valencias (dets. 2001). Vastukaja: Arujärv, Evi. Õhumüügist ja turvateenusest // Sirp (2002) 14. juuni, lk. 3. Essee on ilmunud ka kogumikus: Talvet, Jüri. Tõrjumatu äär. Tartu : Ilmamaa, 2005, lk. 9-30

Aktsionäri kahju hüvitamise nõue aktsiaseltsi ja selle juhtorgani liikmete vastu / Margit Vutt

Index Scriptorium Estoniae

Vutt, Margit, 1968-

2012-01-01

Aktsionäri kahju hüvitamise nõudest rahalise jm kohustuse rikkumise korral. Aktsiaseltsi ja juhtorgani liikmete deliktiõiguslikust vastutusest. Juhtorgani liikmete vastutusest ühinemisel ja jagunemisel. Eesti ja Saksa õiguse ja kohtupraktika võrdlev analüüs

Control de la glucemia en el postoperatorio de cirugía cardíaca: Informe del Consejo de Emergencias de la Sociedad Argentina de Cardiología

Directory of Open Access Journals (Sweden)

Mariano N. Benzadón

2012-02-01

Full Text Available La hiperglucemia en el postoperatorio de cirugía cardÍaca es un hallazgo frecuente asociado a peor evolución, que afecta tanto a diabéticos como no diabéticos. A pesar de las múltiples publicaciones disponibles, aún no existe un abordaje universalmente aceptado a este problema. En una iniciativa originada en el Consejo de Emergencias de la Sociedad Argentina de Cardiología, se convocó a expertos de nuestro medio con el propósito de debatir cómo debe ser el manejo de la glucemia en el paciente crítico cardiovascular. Este documento refleja lo discutido en este evento académico con la intención de resumir los principales aspectos del control de la glucemia en el postoperatorio de cirugía cardíaca.

Kibe kolimine Mustamäel / Jüri Järs, Gerda Koidla, Hilja Rikmann, Siret Mikumets ; intervjueerinud Taimi Nurmiste

Index Scriptorium Estoniae

Järs, Jüri, 1951-

2009-01-01

Intervjuu Tallinna Tehnikaülikooli Raamatukogu direktori Jüri Järsi, asedirektori Gerda Koidla, hoidlakogude peaspetsialisti Hilja Rikmanni ja teenindusosakonna avakogude peaspetsialisti Siret Mikumetsaga raamatukogu uude hoonesse kolimise protsessist ja uutest võimalustest teeninduses

Actualidades del catéter de flotación pulmonar en cirugía cardíaca

OpenAIRE

Fernández Rivera,Bernardo Javier

2006-01-01

El catéter de flotación pulmonar fue introducido hace más de 30 años en la clínica, una de sus principales aplicaciones ha sido la cirugía cardíaca, los valores hemodinámicos obtenidos de su uso se han tratado sin éxito de sustituir por medios no invasivos, existen áreas de controversia acerca de su utilidad, encontrando en la literatura estudios contradictorios acerca del valor de su uso, estos estudios se refieren en general al paciente quirúrgico, y no existen estudios concluyentes en ciru...

Report of the Study Group on Safety of RI and Radiation Uses

International Nuclear Information System (INIS)

Yamazaki, Fumio

1977-01-01

To grasp the present state of RI and radiation usages, a survey by questionnaire was made on the enterprises using small sealed radiation sources, the enterprises carrying out nondestructive tests with large radiation sources and the medical institutions utilizing RIs and radiation. The results of the study aiming at establishing the reasonable and adequate measures of safety management are described together with the survey results. The items studied are the legal regulations, facilities, education and training of workers, and radioactive waste management. (Mori, K.)

Genomic Locus Modulating IOP in the BXD RI Mouse Strains

Directory of Open Access Journals (Sweden)

Rebecca King

2018-05-01

Full Text Available Intraocular pressure (IOP is the primary risk factor for developing glaucoma, yet little is known about the contribution of genomic background to IOP regulation. The present study leverages an array of systems genetics tools to study genomic factors modulating normal IOP in the mouse. The BXD recombinant inbred (RI strain set was used to identify genomic loci modulating IOP. We measured the IOP in a total of 506 eyes from 38 different strains. Strain averages were subjected to conventional quantitative trait analysis by means of composite interval mapping. Candidate genes were defined, and immunohistochemistry and quantitative PCR (qPCR were used for validation. Of the 38 BXD strains examined the mean IOP ranged from a low of 13.2mmHg to a high of 17.1mmHg. The means for each strain were used to calculate a genome wide interval map. One significant quantitative trait locus (QTL was found on Chr.8 (96 to 103 Mb. Within this 7 Mb region only 4 annotated genes were found: Gm15679, Cdh8, Cdh11 and Gm8730. Only two genes (Cdh8 and Cdh11 were candidates for modulating IOP based on the presence of non-synonymous SNPs. Further examination using SIFT (Sorting Intolerant From Tolerant analysis revealed that the SNPs in Cdh8 (Cadherin 8 were predicted to not change protein function; while the SNPs in Cdh11 (Cadherin 11 would not be tolerated, affecting protein function. Furthermore, immunohistochemistry demonstrated that CDH11 is expressed in the trabecular meshwork of the mouse. We have examined the genomic regulation of IOP in the BXD RI strain set and found one significant QTL on Chr. 8. Within this QTL, there is one good candidate gene, Cdh11.

Rad51-Rad52 mediated maintenance of centromeric chromatin in Candida albicans.

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Sreyoshi Mitra

2014-04-01

Full Text Available Specification of the centromere location in most eukaryotes is not solely dependent on the DNA sequence. However, the non-genetic determinants of centromere identity are not clearly defined. While multiple mechanisms, individually or in concert, may specify centromeres epigenetically, most studies in this area are focused on a universal factor, a centromere-specific histone H3 variant CENP-A, often considered as the epigenetic determinant of centromere identity. In spite of variable timing of its loading at centromeres across species, a replication coupled early S phase deposition of CENP-A is found in most yeast centromeres. Centromeres are the earliest replicating chromosomal regions in a pathogenic budding yeast Candida albicans. Using a 2-dimensional agarose gel electrophoresis assay, we identify replication origins (ORI7-LI and ORI7-RI proximal to an early replicating centromere (CEN7 in C. albicans. We show that the replication forks stall at CEN7 in a kinetochore dependent manner and fork stalling is reduced in the absence of the homologous recombination (HR proteins Rad51 and Rad52. Deletion of ORI7-RI causes a significant reduction in the stalled fork signal and an increased loss rate of the altered chromosome 7. The HR proteins, Rad51 and Rad52, have been shown to play a role in fork restart. Confocal microscopy shows declustered kinetochores in rad51 and rad52 mutants, which are evidence of kinetochore disintegrity. CENP-ACaCse4 levels at centromeres, as determined by chromatin immunoprecipitation (ChIP experiments, are reduced in absence of Rad51/Rad52 resulting in disruption of the kinetochore structure. Moreover, western blot analysis reveals that delocalized CENP-A molecules in HR mutants degrade in a similar fashion as in other kinetochore mutants described before. Finally, co-immunoprecipitation assays indicate that Rad51 and Rad52 physically interact with CENP-ACaCse4 in vivo. Thus, the HR proteins Rad51 and Rad52

76 FR 54810 - Submission for Review: 3206-0215, Verification of Full-Time School Attendance, RI 25-49

Science.gov (United States)

2011-09-02

... other technological collection techniques or other forms of information technology, e.g., permitting... or faxed to (202) 395-6974. SUPPLEMENTARY INFORMATION: RI 25-49, Verification of Full-Time School... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: 3206-0215, Verification of Full-Time School...

A scalable implementation of RI-SCF on parallel computers

International Nuclear Information System (INIS)

Fruechtl, H.A.; Kendall, R.A.; Harrison, R.J.

1996-01-01

In order to avoid the integral bottleneck of conventional SCF calculations, the Resolution of the Identity (RI) method is used to obtain an approximate solution to the Hartree-Fock equations. In this approximation only three-center integrals are needed to build the Fock matrix. It has been implemented as part of the NWChem package of portable and scalable ab initio programs for parallel computers. Utilizing the V-approximation, both the Coulomb and exchange contribution to the Fock matrix can be calculated from a transformed set of three-center integrals which have to be precalculated and stored. A distributed in-core method as well as a disk based implementation have been programmed. Details of the implementation as well as the parallel programming tools used are described. We also give results and timings from benchmark calculations

Äriühingud : nende asutamise õiguslik regulatsioon : ajaloolis-võrdlev analüüs (Saksa, Soome ja Euroopa Liit) : [bakalaureusetöö] / Kaire Reispass ; Akadeemia Nord, õigusteaduskond ; juhendaja: Enno Oidermaa

Index Scriptorium Estoniae

Reispass, Kaire

1999-01-01

Äriühingute olemus ja asutamise alused kehtivas seadustikus, Eesti ettevõtlust reguleeriva õigusloome ajalooline ja võrdlev ülevaade, võrdlev ülevaade Saksa, Soome ja Euroopa Liidu äriühinguõigusest

Hoitaja-lääkäri työpari : Hoitotyöntekijöiden ajatuksia ja odotuksia työparimallin toimivuudesta vastaanottotoiminnassa

OpenAIRE

Surakka, Iina; Pitkänen, Satu

2009-01-01

LAUREA-AMMATTIKORKEAKOULU TIIVISTELMÄ Laurea Hyvinkää Sosiaali-, terveys- ja liikunta-ala Hoitotyön koulutusohjelma Pitkänen Satu Surakka Iina Hoitaja-lääkäri työpari. Hoitotyöntekijöiden ajatuksia ja odotuksia työparimallin toimivuudesta vastaanottotoiminnassa Vuosi 2009 Sivu 41 Tämän opinnäytetyön tarkoituksena oli selvittää Hyvinkään vastaanottotoiminnassa työskentelevien hoitajien ajatuksia ja odotuksia liittyen hoitaja-lääkäri työparimalliin. Tutkimuste...

Development of the standard classification system of technical information in the field of RI-biomics and its application to the web system

International Nuclear Information System (INIS)

Jang, Sol Ah; Kim, Joo Yeon; Park, Tai Jin

2014-01-01

RI-Biomics is a new concept that combines radioisotopes (RI) and Biomics. For efficient collection of information, establishment of database for technical information system and its application to the system, there is an increasing need for constructing the standard classification system of technical information by its systematical classification. In this paper, we have summarized the development process of the standard classification system of technical information in the field of RI-Biomics and its application to the system. Constructing the draft version for the standard classification system of technical information was based on that standard classification one in national science and technology in Korea. The final classification system was then derived through the reconstruction and the feedback process based on the consultation from the 7 experts. These results were applied to the database of technical information system after transforming as standard code. Thus, the standard classification system were composed of 5 large classifications and 20 small classifications, and those classification are expected to establish the foundation of information system by achieving the circular structure of collection-analysis-application of information

Evaluación de ansiedad y frecuencia cardíaca: ensayo clínico aleatorizado de la remoción químico-mecánica de caries con papacárieDuoTM. Proyecto piloto

Directory of Open Access Journals (Sweden)

Elisa-Lopes-Craveiro

2013-01-01

Full Text Available Objetivo: Evaluar el grado de ansiedad y frecuencia cardíaca en pacientes infantiles sometidos a tratamiento con PapacárieDuoTM, comparado a un grupo control con el uso del método tradicional (fresa. Métodos: Se desarrolló un ensayo clínico aleatorizado en 7 pacientes infantiles (5 a 11 años. Fueron tratados 2 molares deciduos en cada niño, realizando la aleatorización para los dos grupos (G1= remoción químico-mecánica de la caries con Papacárie DuoTM; G2= remoción de la dentina cariada utilizando fresa con baja velocidad, realizando un procedimiento restaurador similar en ambos (cemento de ionómero de vidrio y control. Se evaluó el tiempo de duración del procedimiento, ansiedad y frecuencia cardíaca. Los datos fueron tabulados con el programa SPSS para Windows (v.17 y analizados estadísticamente mediante el Test Wilcoxon, para los resultados del test VPT; el Test t pareado, para la frecuencia cardíaca, y el Test t para el tiempo de tratamiento, considerándose el nivel de significancia de 5%. Resultados: La media del tiempo para el G1 fue menor (p<0.001, así como la frecuencia cardíaca en el mismo grupo luego de finalizado el tratamiento (p=0.042. No hubo diferencia estadística en las reacciones emocionales antes (p=0.317, durante (p=0.355 y después (p=0.564 de los procedimientos. Conclusión: El tiempo operatorio y la frecuencia cardíaca fueron menores en los niños tratados con el Papacárie DuoTM al ser comparados con los que fueron tratados con tratamiento convencional. Estos hallazgos demuestran las ventajas de los tratamientos conservadores en dientes deciduos.

Päästjate palk tõuseb nii nagu lubatud / Jüri Pihl

Index Scriptorium Estoniae

Pihl, Jüri, 1954-

2007-01-01

Ilmunud ka: Järva Teataja, 6. nov. 2007, lk. 2; Valgamaalane, 6. nov. 2007, lk. 2; Vooremaa, 6. nov. 2007, lk. 2; Põhjarannik, 6. nov. 2007, lk. 4; Vali Uudised, 7. nov. 2007, lk. 2; Sakala, 8. nov. 2007, lk. 2; Severnoje Poberezhje, 8. nov. 2007, lk. 2; Koit, 8. nov. 2007, lk. 6; Sõnumitooja, 14. nov. 2007, lk. 2. Siseminister Jüri Pihl lükkab ümber Keskerakonna väited, et päästeametnike palk ei tõuse ja kinnitab palgatõusu toimumist vastavalt riigieelarve seaduse eelnõule

Two-dimensional echocardiographic and RI angiographic features of aneurysm of the ascending aorta in patients with annuloaortic ectasia

Energy Technology Data Exchange (ETDEWEB)

Nakamura, K.; Suzuki, S.; Satomi, G. (Tokyo Women' s Medical Coll. (Japan). Heart Inst. and Hospital)

1981-03-01

The purpose of this study was to compare the diagnostic value of two-dimensional echocardiography with that of other methods in the detection and localization of aneurysm involving the ascending aorta in patients with annuloaortic ectasia. Two-dimensional echocardiography, RI angiography, CT scan and aortography were performed in 19 patients (12 patients with Marfan's syndrome, 4 with aortitis syndrome and 3 with postoperative perivalvular aneurysm). Eight of 12 patients with Marfan's syndrome had dissection in the ascending aorta which was confirmed at surgery or autopsy. The following observations were obtained. 1) Dissection of the ascending aorta was clearly demonstrated on the two-dimensional echocardiogram in 7 patients by recording the intinal tear and flap, and in these cases the short axis two-dimensional echocardiogram of the ascending aorta was more useful in identifying the site and extent of dissection. 2) In patients with postoperative perivalvular aneurysms, RI angiography proved to be a more useful and sensitive technique in differentiating a leakage into the aneurysm from clots in the aneurysm. 3) CT scanning proved to be an insensitive technique to detect dissection of the ascending aneurysm and to differentiate a leakage from clots in the perivalvular aneurysm. From these observations, we concluded that two-dimensional echocardiography and RI angiography proved to be sensitive techniques in detecting dissection of the ascending aneurysm and evaluating a postoperative aneurysm in patients with annuloaortic ectasia.

Thermal load distribution on the ALT-II limiter of TEXTOR-94 during RI mode operation and during disruptions

International Nuclear Information System (INIS)

Finken, K.H.; Denner, T.; Mank, G.

2000-01-01

Thermographic measurements using an IR scanner have been performed at the pump limiter ALT-II of TEXTOR-94 during RI mode discharges and during disruptions. The measurements on the RI mode discharges were done to complete the TEXTOR database which had shown a structured decay pattern of the deposited power. It was found that the underlying radial heat flux can be described by two exponential decay functions. This structure, which generates an unexpected heat component close to the tangent line, has been observed in all discharge conditions including the RI mode. During disruptions, the heat is released in short pulses with a typical duration of 0.01-0.1 ms. The radial decay length of these pulses has a similar shape to the heat flux during normal discharges: it consists again of a strong component close to the tangent line with a radial decay length of 2-5 mm and probably one with a decay length of the order of 1 cm. The heat is released at the time when the edge electron temperature of the plasma drops, when intense hydrogen and carbon fluxes occur near the walls, and when electrical currents in the limiter blades are excited. In a tentative interpretation, the temporal and spatial structure of the heat pulse is attributed to the presence and growth of a laminar zone at the plasma edge, which is connected with the ergodization of the plasma edge during a disruption. (author)

231. Cirugía cardíaca en adultos con cardiopatías congénitas: ¿qué pacientes y patologías intervenimos actualmente?

Directory of Open Access Journals (Sweden)

E.C. Ruiz-Solano

2012-04-01

Conclusiones: La cirugía congénita sobre pacientes adultos representa una actividad de relevancia en la cirugía cardíaca de hoy día. Nuestros resultados evidencian que este tipo de intervenciones se puede llevar a cabo con una baja morbimortalidad.

Eesti tippteadlaste panus maailma : päästvad bakterid ja täiustatud elektroonika / koost. Jüri Allik

Index Scriptorium Estoniae

2007-01-01

Jüri Allik lappas maailma suurimat teaduskirjanduse andmebaasi ISI Web of Science. Enimviidatud Eesti teadlased on: Jaan Aarik, Jaak Jürimäe, Mati Karelson, Marco Kirm, Eero Vasar, Mihkel Zilmer, Ülo Niinemets, Kaupo Kukli, Enn Lust

Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells.

Science.gov (United States)

McPherson, Victor A; Everingham, Stephanie; Karisch, Robert; Smith, Julie A; Udell, Christian M; Zheng, Jimin; Jia, Zongchao; Craig, Andrew W B

2009-01-01

This study investigates the roles of Fer-CIP4 homology (FCH)-Bin/amphiphysin/Rvs (F-BAR) and SH2 domains of Fes protein tyrosine kinase in regulating its activation and signaling downstream of the high-affinity immunoglobulin G (IgE) receptor (FcepsilonRI) in mast cells. Homology modeling of the Fes F-BAR domain revealed conservation of some basic residues implicated in phosphoinositide binding (R113/K114). The Fes F-BAR can bind phosphoinositides and induce tubulation of liposomes in vitro. Mutation of R113/K114 to uncharged residues (RK/QQ) caused a significant reduction in phosphoinositide binding in vitro and a more diffuse cytoplasmic localization in transfected COS-7 cells. RBL-2H3 mast cells expressing full-length Fes carrying the RK/QQ mutation show defects in FcepsilonRI-induced Fes tyrosine phosphorylation and degranulation compared to cells expressing wild-type Fes. This correlated with reduced localization to Lyn kinase-containing membrane fractions for the RK/QQ mutant compared to wild-type Fes in mast cells. The Fes SH2 domain also contributes to Fes signaling in mast cells, via interactions with the phosphorylated FcepsilonRI beta chain and the actin regulatory protein HS1. We show that Fes phosphorylates C-terminal tyrosine residues in HS1 implicated in actin stabilization. Thus, coordinated actions of the F-BAR and SH2 domains of Fes allow for coupling to FcepsilonRI signaling and potential regulation the actin reorganization in mast cells.

Professor Jüri Talvetist sai Ida-Lääne akadeemia liige / intervjueerinud Rein Veidemann

Index Scriptorium Estoniae

Talvet, Jüri, 1945-

2011-01-01

Intervjuu Tartu ülikooli maailmakirjanduse professori Jüri Talvetiga luulefestivalist Curtea de Argeş ("Nopţile de Poezie de la Curtea de Argeş") ja tema rumeenia keelde tõlgitud luulekogust „Unest, lumest” ("De din somn, de din zăpadă" - tõlkija Dumitru M. Ion), mida autor seal esitlemas käis ning Ida-Lääne akadeemiast (Academia Internationala Orient-Occident), mille tegevliikmeks ta valiti

Drenagem anômala total das veias pulmonares, em sua forma infracardíaca: desafio diagnóstico Infracardiac total anomalous pulmonary venous drainage: a diagnostic challenge

Directory of Open Access Journals (Sweden)

Célia M. C. Silva

2007-04-01

Full Text Available No período neonatal, a drenagem anômala total das veias pulmonares, em sua forma infracardíaca, pode ser erroneamente diagnosticada como desconforto respiratório decorrente de diferentes etiologias. No pré-operatório, a ecocardiografia bidimensional com Doppler orientado pelo mapeamento de fluxo em cores pode definir o local exato da drenagem e o padrão de retorno venoso pulmonar, permitindo, dessa forma, que a cirurgia cardíaca seja realizada imediatamente antes que ocorra qualquer dano clínico.Infracardiac total anomalous pulmonary venous drainage can be erroneously diagnosed as respiratory distress of several different etiologies during the neonatal period. A cross-sectional echocardiography study with Doppler color flow mapping can preoperatively determine the precise drainage site and pulmonary venous return pattern, thereby allowing cardiac surgery to be performed promptly, prior to any clinical deterioration.

76 FR 22938 - Submission for Review: RI 25-37, Evidence To Prove Dependency of a Child

Science.gov (United States)

2011-04-25

... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: RI 25-37, Evidence To Prove Dependency of a..., Evidence to Prove Dependency of a Child. As required by the Paperwork Reduction Act of 1995 (Pub. L. 104-13... Dependency of a Child, is designed to collect sufficient information for the Office of Personnel Management...

Aplicabilidade dos resultados de enfermagem em pacientes com insuficiência cardíaca e volume de líquidos excessivo

Directory of Open Access Journals (Sweden)

Joelza Celesilvia Chisté Linhares

Full Text Available RESUMO Objetivo Testar a aplicabilidade clínica da Nursing Outcomes Classification em pacientes com insuficiência cardíaca descompensada e Diagnóstico de Enfermagem Volume de Líquidos Excessivo. Métodos Estudo longitudinal conduzido em duas etapas em um hospital universitário no ano de 2013. Na primeira etapa, utilizou-se a validação por consenso de especialistas para selecionar os resultados de enfermagem e os indicadores relacionados ao diagnóstico de enfermagem; na segunda, foi realizado um estudo longitudinal para avaliação clínica dos pacientes, utilizando-se o instrumento contendo os resultados e indicadores produzidos no consenso. Resultados Foram realizadas avaliações em 17 pacientes. Na avaliação clínica, mensuraram-se os resultados de enfermagem através da avaliação de seus indicadores. Seis resultados apresentaram aumento nos escores, quando comparados às médias da primeira e da última avaliação. A utilização da Nursing Outcomes Classification na prática clínica demonstrou melhora dos pacientes internados por insuficiência cardíaca descompensada. Conclusão A Nursing Outcomes Classification foi sensível às alterações no quadro clínico dos pacientes.

Some Challenges of an “Upside Down” Nitrogen Budget – Science and Management in Greenwich Bay, RI (USA)

Science.gov (United States)

When nutrients impact estuarine water quality, scientists and managers instinctively focus on quantifying and controlling land-based sources. However, in Greenwich Bay, RI, the estuary opens onto a larger and more intensively fertilized coastal water body (Narragansett Bay). Prev...

Bimedial faden recession versus augmented medial rectus recession in the treatment of high ac/a ratio partially accommodative esotropia with large distant near disparity

Directory of Open Access Journals (Sweden)

Mohammed F Farid

2016-01-01

Faden recession achieves marginal superior control of DND and high AC/A ratio in convergence excess partially accommodative ET. Augmented recession also works well with the possible development of consecutive exotropia in cases with extremely high DND. This study recommends Augmented recession for cases with mild to moderate DND and Faden recession for cases with extremely large DND.

Aspectos psicosociales de la enfermedad celíaca en España: una vida libre de gluten

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Julián Rodríguez ALMAGRO

Full Text Available RESUMEN Objetivo: La celiaquía como enfermedad crónica tiene una alta prevalencia en nuestra sociedad. El artículo analiza los aspectos psicosociales de la enfermedad celíaca en los diferentes entornos, valorando el impacto de la implantación de una dieta estricta libre de gluten. Métodos: Estudio cualitativo entre los meses de Enero del 2013 a Abril del 2013 en el cual, a través de la teoría fundamentada y el análisis de contenido, se ha profundizado en el análisis de las entrevistas semiestructuradas a personas con enfermedad celíaca en España. Se realizaron llamamientos a traves de las redes sociales y grupos de celíacos hasta llegar a la saturación teórica, que determinó el tamaño final de la muestra de 24 personas. Resultados: Educación Sanitaria, Aislamiento social, soledad y desconocimiento social emergieron como categorías centrales en la experiencia de adopción de la dieta libre de gluten a partir del diagnóstico de celiaquía. Conclusión: Los profesionales deben promover y apoyar estrategias de apoyo social basadas en una comprensión íntegra de las experiencias de desarraigo y marginación que los pacientes celíacos experimentan en sus relaciones sociales a través de la comida. Se requiere un aumento de la educación sanitaria para entender e integrar el impacto psicosocial del diagnóstico de celiaquía y la dieta libre de gluten.

Valor preditivo da frequência cardíaca em repouso do teste ergométrico na mortalidade

Directory of Open Access Journals (Sweden)

Jaqueline Eilert Fagundes

2010-12-01

Full Text Available FUNDAMENTO: A frequência cardíaca em repouso (cuja média está entre 60 e 80 bpm é uma das mais simples variáveis cardiovasculares e tem sido considerada como um preditor de mortalidade cardiovascular e geral. OBJETIVO: Avaliar o valor preditivo da frequência cardíaca em repouso (FCR, antes do teste ergométrico (TE, na mortalidade cardiovascular (CV e geral. MÉTODOS: Estudo de caso-controle, que utilizou informações contidas nos bancos de dados do laboratório de ergometria de um hospital especializado em cardiologia e os registros de óbitos da Secretaria da Saúde em uma cidade do sul do Brasil, de janeiro de 1995 a junho de 2007. Foram analisados 7.055 pacientes, sendo 1.645 (23,3% do grupo caso (óbitos e 5.410 (76,7% do grupo controle (vivos. Foi calculado o ponto de corte da FCR para mortalidade, através da curva ROC e realizada a análise multivariada para as variáveis selecionadas. Os desfechos foram mortalidade CV e geral. RESULTADOS: A incidência de mortalidade CV foi de 674 casos (9,5%; a FCR > 78 bpm foi o ponto de corte. Após ajustado para as variáveis selecionadas, o odds ratio (OR para FCR > 78 bpm foi de 3,5 (IC 95% = 2,9 - 4,2 para mortalidade CV e 3,6 (IC 95% = 3,2 - 4,0 para mortalidade geral. CONCLUSÃO: A FCR > 78 bpm é um preditor independente de mortalidade cardiovascular e geral.

Box H/ACA snoRNAs are preferred substrates for the trimethylguanosine synthase in the divergent unicellular eukaryote Trichomonas vaginalis

Science.gov (United States)

Simoes-Barbosa, Augusto; Chakrabarti, Kausik; Pearson, Michael; Benarroch, Delphine; Shuman, Stewart; Johnson, Patricia J.

2012-01-01

The 2,2,7-trimethylguanosine caps of eukaryal snRNAs and snoRNA are formed by the enzyme Tgs1, which catalyzes sequential guanine-N2 methylations of m7G caps. Atypically, in the divergent unicellular eukaryote Trichomonas vaginalis, spliceosomal snRNAs lack a guanosine cap and the recombinant T. vaginalis trimethylguanosine synthase (TvTgs) produces only m2,7G in vitro. Here, we show by direct metabolic labeling that endogenous T. vaginalis RNAs contain m7G, m2,7G, and m2,2,7G caps. Immunodepletion of TvTgs from cell extracts and TvTgs add-back experiments demonstrate that TvTgs produces m2,7G and m2,2,7G caps. Expression of TvTgs in yeast tgs1Δ cells leads to the formation of m2,7G and m2,2,7G caps and complementation of the lethality of a tgs1Δ mud2Δ strain. Whereas TvTgs is present in the nucleus and cytosol of T. vaginalis cells, TMG-containing RNAs are localized primarily in the nucleolus. Molecular cloning of anti-TMG affinity-purified T. vaginalis RNAs identified 16 box H/ACA snoRNAs, which are implicated in guiding RNA pseudouridylation. The ensemble of new T. vaginalis H/ACA snoRNAs allowed us to predict and partially validate an extensive map of pseudouridines in T. vaginalis rRNA. PMID:22847815

The residual and direct effects of reduced-risk and conventional miticides on twospotted spider mites, Tetranychus urticae (Acari: Tetranychidae) and predatory mites (Acari: Phytoseiidae)

International Nuclear Information System (INIS)

Liburd, O.E.; White, J.C.; Rhodes, E.M.; Browdy, A.A.

2007-01-01

The residual effects of several reduced-risk and conventional miticides were evaluated in strawberries (Fragaria × ananassa Duchesne) on the twospotted spider mite (TSSM), Tetranychus urticae Koch (Acari: Tetranychidae) and on 2 predatory mites, Neoseiulus californicus McGregor and Phytoseiulus persimilis Athias-Henriot (Acari: Phytoseiidae). Experiments were conducted in the laboratory and greenhouse. The greenhouse experiments also tested the direct effects of the miticides on TSSM. The efficacy of conventional and reduced-risk miticides was evaluated on strawberry leaf discs and on whole plants for control of TSSM. Furthermore, the residual effects of these miticides were evaluated on whole strawberry plants against selective predatory mites. For TSSM, 5 treatments were evaluated: a conventional miticide; fenbutatin-oxide (Vendex[reg]) and 3 reduced-risk miticides; binfenazate (Acramite 50WP[reg]), activated garlic extract (Repel[reg]), sesame seed and castor oil (Wipeout[reg]), and a water-treated control. For predatory mites, the residual effects of only Acramite[reg] and Vendex[reg] were evaluated. Acramite[reg] was the most effective acaricide in reducing TSSM populations in both the laboratory and greenhouse experiments. Vendex[reg] and Wipeout[reg] were also effective in the laboratory, but did not cause significant reduction of TSSM in the greenhouse. Repel[reg] was the least effective of the 4 pesticides evaluated. Neither Acramite[reg] nor Vendex[reg] had a significant effect on either predatory mite species. However, there appeared to be more predatory mites on the Vendex[reg]-treated plants than on the Acramite[reg]-treated plants. There were significantly more predatory mites of both species on the cue plants, which were inoculated with TSSM versus the non-cue plants, which were not inoculated. (author) [es

Field measurement of the piping system vibration of Ko-Ri unit 4 during the load-following operation

International Nuclear Information System (INIS)

Chung, Tae-Young; Hong, Sung-Yull; Kim, Bum-Nyun.

1989-01-01

During the load-following operation of nuclear power plants, flow rate, temperature, and pressure in the piping system can be varied by changing the electric power output level, and these variations can cause different vibration phenomena in the piping system. The piping system vibration is important because it is directly related to the dynamic stress of the piping system and can affect the life of the piping system through structural fatigue. An assessment of vibration levels for the classes II and III piping systems of the Ko-Ri Unit 4950-MW nuclear power plant was performed according to the given pattern of the load-following operation to study its feasibility from the viewpoint of piping system vibration. The classes II and III piping system vibration of the Ko-Ri Unit 4 may not cause any potential problem under the given pattern of the load-following operation; however, it is recommended that long-term operation in the 85 to 95% power range be avoided as much as possible

Interjööri kujunduse ja moekunsti seosed ja vastasmõjud / Jane Kukk

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Kukk, Jane

2011-01-01

Teoreetilise uurimuse eesmärgiks oli vaadelda disaini laiemalt, kõrvutades moe- ja interjööridisaini, looduskeskkonna, sotsiaalpoliitilise ja kultuuriruumi mõjutusi sellele ning jõudes järeldusele, et kõik disaini valdkonnad on tänu disainimise protsessi samale mudelile sarnased, on omavahel seotud ja võivad üksteist mõjutada, eriti tingimustes, kus moetööstus on laiendanud oma tegevust interjööri valdkonda, soovides luua terviklikku elustiili paketti tänapäeva tarbimisühiskonnas

O impacto do CPAP na reabilitação cardíaca de pacientes com ICC: relato de caso El impacto del CPAP en la rehabilitación cardíaca de pacientes con ICC: caso clínico The impact of continuous positive airway pressure (CPAP on the cardiac rehabilitation of patients with congestive heart failure: case report

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Murillo Frazão de Lima e Costa

2010-07-01

Full Text Available A insuficiência cardíaca congestiva é uma patologia que limita a função física do paciente. Neste estudo foi analisada uma paciente, realizando um programa de reabilitação cardíaca associado à pressão positiva contínua nas vias aéreas, aferindo-se antes do estudo e após 6 semanas, o teste de caminhada de 6 minutos (TC6M, questionário de qualidade de vida e ecocardiograma. A paciente aumentou a distância no TC6M de 152,5 m para 520,44 m. O questionário Minnesota reduziu de 62 para 18. A fração de ejeção subiu de 33% para 36%. Na paciente estudada a conduta melhorou o desempenho físico e a qualidade de vida.La insuficiencia cardíaca congestiva es una patología que limita la función física del paciente. En este estudio fue analizada una paciente, realizando un programa de rehabilitación cardíaca asociado a la presión positiva continua en las vías aéreas, realizando antes del estudio y después de 6 semanas, el test de caminata de 6 minutos (TC6M, cuestionario de calidad de vida y ecocardiograma. La paciente aumentó la distancia en el TC6M de 152,5 m a 520,44 m. El cuestionario Minnesota redujo de 62 a 18. La fracción de eyección subió de 33% a 36%. En la paciente estudiada la conducta mejoró el desempeño físico y la calidad de vida.Congestive heart failure is a pathology that limits the patient's physical function. This study analyzed one patient who was submitted to a cardiac rehabilitation program associated to Continuous Positive Airway Pressure (CPAP, by assessing the results of the six-minute walk test (6MWT and a questionnaire on the quality of life and performing an echocardiographic assessment before the study and after six weeks. The distance walked by the patient increased from 152.5 m to 520.44 m at the 6MWT. The Minnesota questionnaire score decreased from 62 to 18. Ejection fraction increased from 33% to 36%. Therefore, the management chosen for this case improved the patient's physical performance

Strongyloides ratti: implication of mast cell-mediated expulsion through FcεRI-independent mechanisms

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Watanabe K.

2009-09-01

Full Text Available In order to examine whether FcεRI-dependent degranulation of intestinal mast cells is required for expulsion of intestinal nematode Strongyloides ratti, CD45 exon6-deficient (CD45-/- mice were inoculated with S. ratti. In CD45-/- mice, egg excretion in feces persisted for more than 30 days following S. ratti larvae inoculation, whereas in wild-type (CD45+/+ mice, the eggs completely disappeared by day 20 post-infection. The number of intestinal mucosal mast cells, which are known effector cells for the expulsion of S. ratti, was 75% lower in CD45-/- mice compared with that in CD45+/+ mice. Adoptive transfer of wild-type T cells from CD45+/+ mice into CD45-/- mice reduced the duration of S. ratti infection to comparable levels observed in CD45+/+ mice, with concomitant increases in intestinal mucosal mast cells. These results showed that CD45 is not involved in the effector function of intestinal mucosal mast cells against S. ratti infection. Since FcεRI-dependent degranulation of mast cells is completely impaired in these CD45 knockout mice, we conclude that FcεRIdependent degranulation is not required in the protective function of intestinal mucosal mast cells against primary infection of S. ratti.

Cuidados imediatos no pós-operatório de cirurgia cardíaca Immediate post-operative care following cardiac surgery

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Paulo Ramos David João

2003-11-01

Full Text Available OBJETIVO: Apresentar uma rotina de atendimento para crianças submetidas à cirurgia cardíaca. FONTES DOS DADOS: Realizada revisão bibliográfica através de bancos de dados (Medline, Mdconsult, PubMed, analisando as condutas sugeridas por diversos serviços fora do Brasil e comparando com a rotina de atendimento no Hospital Infantil Pequeno Príncipe, de Curitiba, onde foram realizadas cerca de 8.000 cirurgias cardíacas desde 1977 até abril de 2003. SÍNTESE DOS DADOS: O serviço citado é referência em cardiologia e cirurgia cardíaca no estado do Paraná e estados vizinhos. A evolução das condições de diagnóstico, preparo da equipe clínica e cirúrgica, unidade de terapia intensiva (UTI melhor equipada com monitorização mais avançada, equipe da UTI com pessoal treinado em todas as áreas para fazer pós-operatório de cirurgia cardíaca, estrutura hospitalar adequada, oferecendo atendimento avançado em todas as especialidades pediátricas e paramédicas, fazem com que o resultado das intervenções cirúrgicas realizadas em crianças com cardiopatias congênitas ou adquiridas, principalmente nos recém-nascidos e lactentes jovens com cardiopatias complexas, apresente sensível melhora quando comparado com anos anteriores. CONCLUSÃO: As crianças com cardiopatias, principalmente as complexas, devem ser encaminhadas para um local que seja centro de referência, onde haja condições para um atendimento global no pré, per e pós-operatório.OBJECTIVE: To present a care routine for children submitted to heart surgery. SOURCE OF DATA: Literature review of Medscape, MD Consult and PubMed. Analysis of the suggested conducts adopted by various services from different countries and comparison with the care routine at the Pequeno Príncipe Children's Hospital (Curitiba, state of Paraná, where approximately 8,000 heart surgeries were performed in children from 1977 to April 2003. SUMMARY OF THE FINDINGS: Our hospital is a reference

Spontaneous food allergy in Was-/- mice occurs independent of FcεRI-mediated mast cell activation.

Science.gov (United States)

Lexmond, W S; Goettel, J A; Sallis, B F; McCann, K; Rings, E H H M; Jensen-Jarolim, E; Nurko, S; Snapper, S B; Fiebiger, E

2017-12-01

Food allergies are a growing health problem, and the development of therapies that prevent disease onset is limited by the lack of adjuvant-free experimental animal models. We compared allergic sensitization in patients with food allergy or Wiskott-Aldrich syndrome (WAS) and defined whether spontaneous disease in Was -/- mice recapitulates the pathology of a conventional disease model and/or human food allergy. Comparative ImmunoCAP ISAC microarray was performed in patients with food allergy or WAS. Spontaneous food allergy in Was -/- mice was compared to an adjuvant-based model in wild-type mice (WT-OVA/alum). Intestinal and systemic anaphylaxis was assessed, and the role of the high-affinity IgE Fc receptor (FcεRI) in allergic sensitization was evaluated using Was -/- Fcer1a -/- mice. Polysensitization to food was detected in both WAS and food-allergic patients which was recapitulated in the Was -/- model. Oral administration of ovalbumin (OVA) in Was -/- mice induced low titers of OVA-specific IgE compared to the WT-OVA/alum model. Irrespectively, 79% of Was -/- mice developed allergic diarrhea following oral OVA challenge. Systemic anaphylaxis occurred in Was -/- mice (95%) with a mortality rate >50%. Spontaneous sensitization and intestinal allergy occurred independent of FcεRI expression on mast cells (MCs) and basophils. Was -/- mice provide a model of food allergy with the advantage of mimicking polysensitization and low food-antigen IgE titers as observed in humans with clinical food allergy. This model will facilitate studies on aberrant immune responses during spontaneous disease development. Our results imply that therapeutic targeting of the IgE/FcεRI activation cascade will not affect sensitization to food. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

Manejo nutricional de la enfermedad celíaca Nutritional management of the celiac disease

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Daris I. González Hernández

2006-06-01

Full Text Available La enfermedad celíaca es una causa importante de malaabsorción en la niñez. Se caracteriza por una intolerancia total y permanente al gluten que contiene la fracción proteica del trigo y otros cereales. La patogenia de la enfermedad es multifactorial y tiene un cuadro clínico variado, en el cual predominan los síntomas de malaabsorción y la desnutrición. La dieta exenta de gluten es la parte más importante de la terapéutica, además de hacer frente a las deficiencias nutricionales. Se hace una revisión del manejo dietético y la educación nutricional del paciente y sus familiares, con énfasis en los alimentos que pueden contener gluten de forma enmascarada.

Manager- bändikarjääri disainija ja kokkusõlmija / Paul Cheeetham, Tapio Korjus, Petri H. Lunden ...[jt.

Index Scriptorium Estoniae

Cheetham, Paul

2010-01-01

Muusikamanageride Paul Cheethami, Tapio Korjuse, Petri H. Lundeni, Kari Pössi ja Rasmus Stolbergi arvamusi oma tööst ja nõuannetest eesti ansamblitele, kes tahavad oma karjääri teha rahvusvahelisel areenil

Cistatina C como predictor de síndrome cardio-renal y mal pronóstico en pacientes internados por insuficiencia cardíaca aguda y función renal normal

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Iván Constantin

2016-01-01

Full Text Available Introducción: El desarrollo de disfunción renal en el contexto de una falla cardíaca aguda se conoce como síndrome cardiorrenal (SCR tipo 1. El empeoramiento de la función renal (EFR durante la internación es un predictor de mal pronóstico. La cistatina C ha surgido como un marcador de función renal alternativo a la creatinina. Objetivo: Demostrar la utilidad clínica de la cistatina C como predictor de EFR y factor pronóstico en pacientes con insuficiencia cardíaca aguda y sin disfunción renal evaluada por creatinina al ingreso. Material y métodos: Se llevó a cabo un estudio observacional, prospectivo, de pacientes consecutivos con diagnóstico de insuficiencia cardíaca aguda y sin disfunción renal, definida como un valor de creatinina < 1,3 mg/dl al ingreso. Se realizó un dosaje de cistatina C al ingreso. El punto final primario fue EFR y los secundarios fueron mortalidad hospitalaria, mortalidad total y reinternación por insuficiencia cardíaca. Resultados: Se incluyeron 166 pacientes con una mediana de edad de 85 años (IIC 77,7-89. La incidencia de EFR fue del 29,7%, con una mortalidad hospitalaria del 3,1% y una mortalidad total del 24,4%. La mediana de seguimiento fue de 193 días. El valor de cistatina C fue significativamente mayor en los pacientes que desarrollaron EFR (1,72 ± 0,58 mg/dl vs. 1,51 ± 0,41 mg/dl; p = 0,03 y en los pacientes que murieron en el seguimiento (1,76 ± 0,49 mg/dl vs. 1,51 ± 0,46 mg/dl; p = 0,004. La cistatina C resultó un predictor independiente de mortalidad (OR 3,03, IC 95% 1,22-7,47 y de EFR (OR 2,38, IC 95% 1,02- 5,5 en el análisis multivariado. Se halló un punto de corte óptimo de 1,6 mg/dl de cistatina, con una sensibilidad del 61,22% y una especificidad del 60,34% para el desarrollo de EFR y del 61,54% y 61,98%, respectivamente, para mortalidad total. Conclusión: El valor de cistatina C al ingreso es predictor de desarrollo de EFR durante la internación y de mayor mortalidad en

Davallia mariesii Moore Improves FcεRI-Mediated Allergic Responses in the Rat Basophilic Leukemia Mast Cell Line RBL-2H3 and Passive Cutaneous Anaphylaxis in Mice

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Hyun Ju Do

2017-01-01

Full Text Available Davallia mariesii Moore (Drynaria rhizome extract (DRE is widely known for its efficacy in treating inflammation, arteriosclerosis, and bone injuries. This study evaluated whether treatment with DRE inhibited FcɛRI-mediated allergic responses in the RBL-2H3 mast cells and investigated the early- and late-phase mechanisms by which DRE exerts its antiallergic effects. IgE anti-DNP/DNP-HSA-sensitized RBL-2H3 mast cells were tested for cytotoxicity to DRE, followed by the assessment of β-hexosaminidase release. We measured the amounts of inflammatory mediators (e.g., histamine, PGD2, TNF-α, IL-4, and IL-6 and examined the expression of genes involved in arachidonate and FcεRI signaling pathways. In addition, we confirmed the antiallergic effects of DRE on passive cutaneous anaphylaxis (PCA in mice. DRE inhibited RBL-2H3 mast cell degranulation and production of allergic mediators in them. In early allergic responses, DRE reduced expression of FcεRI signaling-related genes (e.g., Syk, Lyn, and Fyn and extracellular signal-regulated kinase phosphorylation in mast cells. In late allergic responses, DRE reduced PGD2 release and COX-2 expression and cPLA2 phosphorylation in FcɛRI-mediated mast cells. Lastly, 250–500 mg/kg DRE significantly attenuated the IgE-induced PCA reaction in mice. These findings provide novel information on the molecular mechanisms underlying the antiallergic effects of DRE in FcɛRI-mediated allergic responses.

Uudised : Hooaja lõppkontsert. Tallinna Kammerorkester lõpetab hooaja. Tüüri autorikontsert New Yorgis / Leelo Kõlar

Index Scriptorium Estoniae

Kõlar, Leelo, 1927-

2000-01-01

Täna toimuvast Eesti Kontserdi hooaja lõppkontserdist, kus tuleb ettekandele G. Mahleri 3. sümfoonia. Tallinna Kammerorkestri hooaja viimasest kontserdist sarjas "Mozart +" 20. ja 21. mail. 12. mail andis Absolute Ensemble K. Järvi juhatusel sarja "Heliloojate portreed" raames kontserdi E.-S. Tüüri loomingust

Kõltsu mõisa peahoone = Kõltsu manor house / Jüri Irik, Kaire Kemp-Tišler ; intervjueerinud Margit Mutso

Index Scriptorium Estoniae

Irik, Jüri, 1961-

2011-01-01

Kõltsu mõisa peahoone restaureerimisest. Arhitekt Jüri Irik (AB Ehala & Irik). Sisearhitektid Kaire Kemp-Tišler, Ea Andla (SAB ArtAku). Maastikuarhitektid Ülle Grišakov, Triin Järve. Vitraažide autor Valev Sein. Sepiste autor Heigo Jelle