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Sample records for absolute age estimates

  1. Absolute and estimated values of macular pigment optical density in young and aged Asian participants with or without age-related macular degeneration.

    Science.gov (United States)

    Ozawa, Yoko; Shigeno, Yuta; Nagai, Norihiro; Suzuki, Misa; Kurihara, Toshihide; Minami, Sakiko; Hirano, Eri; Shinoda, Hajime; Kobayashi, Saori; Tsubota, Kazuo

    2017-08-29

    Lutein and zeaxanthin are suggested micronutrient supplements to prevent the progression of age-related macular degeneration (AMD), a leading cause of blindness worldwide. To monitor the levels of lutein/zeaxanthin in the macula, macular pigment optical density (MPOD) is measured. A commercially available device (MPSII®, Elektron Technology, Switzerland), using technology based on heterochromatic flicker photometry, can measure both absolute and estimated values of MPOD. However, whether the estimated value is applicable to Asian individuals and/or AMD patients remains to be determined. The absolute and estimated values of MPOD were measured using the MPSII® device in 77 participants with a best-corrected visual acuity (BCVA) > 0.099 (logMAR score). The studied eyes included 17 young (20-29 years) healthy, 26 aged (>50 years) healthy, 18 aged and AMD-fellow, and 16 aged AMD eyes. The mean BCVA among the groups were not significantly different. Both absolute and estimated values were measurable in all eyes of young healthy group. However, absolute values were measurable in only 57.7%, 66.7%, and 43.8%, of the aged healthy, AMD-fellow, and AMD groups, respectively, and 56.7% of the eyes included in the 3 aged groups. In contrast, the estimated value was measurable in 84.6%, 88.9% and 93.8% of the groups, respectively, and 88.3% of eyes in the pooled aged group. The estimated value was correlated with absolute value in individuals from all groups by Spearman's correlation coefficient analyses (young healthy: R 2  = 0.885, P = 0.0001; aged healthy: R 2  = 0.765, P = 0.001; AMD-fellow: R 2  = 0.851, P = 0.0001; and AMD: R 2  = 0.860, P = 0.013). Using the estimated value, significantly lower MPOD values were found in aged AMD-related eyes, which included both AMD-fellow and AMD eyes, compared with aged healthy eyes by Student's t-test (P = 0.02). Absolute, in contrast to estimated, value was measurable in a limited number of aged participants

  2. The gender- and age-specific 10-year and lifetime absolute fracture risk in Tromso, Norway

    International Nuclear Information System (INIS)

    Ahmed, Luai A.; Schirmer, Henrik; Bjornerem, Ashild; Emaus, Nina; Jorgensen, Lone; Stormer, Jan; Joakimsen, Ragnar M.

    2009-01-01

    Aim of this study is to estimate the gender- and age-specific 10-year and lifetime absolute risks of non-vertebral and osteoporotic (included hip, distal forearm and proximal humerus) fractures in a large cohort of men and women. This is a population-based 10 years follow-up study of 26,891 subjects aged 25 years and older in Tromso, Norway. All non-vertebral fractures were registered from 1995 throughout 2004 by computerized search in radiographic archives. Absolute risks were estimated by life-table method taking into account the competing risk of death. The absolute fracture risk at each year of age was estimated for the next 10 years (10-year risk) or up to the age of 90 years (lifetime risk). The estimated 10-year absolute risk of all non-vertebral fracture was higher in men than women before but not after the age of 45 years. The 10-year absolute risk for non-vertebral and osteoporotic fractures was over 10%, respectively, in men over 65 and 70 years and in women over 45 and 50 years of age. The 10-year absolute risks of hip fractures at the age of 65 and 80 years were 4.2 and 18.6% in men, and 9.0 and 24.0% in women, respectively. The risk estimates for distal forearm and proximal humerus fractures were under 5% in men and 13% in women. The estimated lifetime risks for all fracture locations were higher in women than men at all ages. At the age of 50 years, the risks were 38.1 and 24.8% in men and 67.4 and 55.0% in women for all non-vertebral and osteoporotic fractures, respectively. The estimated gender- and age-specific 10-year and lifetime absolute fracture risk were higher in Tromso than in other populations. The high lifetime fracture risk reflects the increased burden of fractures in this cohort

  3. Variance computations for functional of absolute risk estimates.

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    Pfeiffer, R M; Petracci, E

    2011-07-01

    We present a simple influence function based approach to compute the variances of estimates of absolute risk and functions of absolute risk. We apply this approach to criteria that assess the impact of changes in the risk factor distribution on absolute risk for an individual and at the population level. As an illustration we use an absolute risk prediction model for breast cancer that includes modifiable risk factors in addition to standard breast cancer risk factors. Influence function based variance estimates for absolute risk and the criteria are compared to bootstrap variance estimates.

  4. A global algorithm for estimating Absolute Salinity

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    McDougall, T. J.; Jackett, D. R.; Millero, F. J.; Pawlowicz, R.; Barker, P. M.

    2012-12-01

    The International Thermodynamic Equation of Seawater - 2010 has defined the thermodynamic properties of seawater in terms of a new salinity variable, Absolute Salinity, which takes into account the spatial variation of the composition of seawater. Absolute Salinity more accurately reflects the effects of the dissolved material in seawater on the thermodynamic properties (particularly density) than does Practical Salinity. When a seawater sample has standard composition (i.e. the ratios of the constituents of sea salt are the same as those of surface water of the North Atlantic), Practical Salinity can be used to accurately evaluate the thermodynamic properties of seawater. When seawater is not of standard composition, Practical Salinity alone is not sufficient and the Absolute Salinity Anomaly needs to be estimated; this anomaly is as large as 0.025 g kg-1 in the northernmost North Pacific. Here we provide an algorithm for estimating Absolute Salinity Anomaly for any location (x, y, p) in the world ocean. To develop this algorithm, we used the Absolute Salinity Anomaly that is found by comparing the density calculated from Practical Salinity to the density measured in the laboratory. These estimates of Absolute Salinity Anomaly however are limited to the number of available observations (namely 811). In order to provide a practical method that can be used at any location in the world ocean, we take advantage of approximate relationships between Absolute Salinity Anomaly and silicate concentrations (which are available globally).

  5. A global algorithm for estimating Absolute Salinity

    Directory of Open Access Journals (Sweden)

    T. J. McDougall

    2012-12-01

    Full Text Available The International Thermodynamic Equation of Seawater – 2010 has defined the thermodynamic properties of seawater in terms of a new salinity variable, Absolute Salinity, which takes into account the spatial variation of the composition of seawater. Absolute Salinity more accurately reflects the effects of the dissolved material in seawater on the thermodynamic properties (particularly density than does Practical Salinity.

    When a seawater sample has standard composition (i.e. the ratios of the constituents of sea salt are the same as those of surface water of the North Atlantic, Practical Salinity can be used to accurately evaluate the thermodynamic properties of seawater. When seawater is not of standard composition, Practical Salinity alone is not sufficient and the Absolute Salinity Anomaly needs to be estimated; this anomaly is as large as 0.025 g kg−1 in the northernmost North Pacific. Here we provide an algorithm for estimating Absolute Salinity Anomaly for any location (x, y, p in the world ocean.

    To develop this algorithm, we used the Absolute Salinity Anomaly that is found by comparing the density calculated from Practical Salinity to the density measured in the laboratory. These estimates of Absolute Salinity Anomaly however are limited to the number of available observations (namely 811. In order to provide a practical method that can be used at any location in the world ocean, we take advantage of approximate relationships between Absolute Salinity Anomaly and silicate concentrations (which are available globally.

  6. Absolute Navigation Information Estimation for Micro Planetary Rovers

    Directory of Open Access Journals (Sweden)

    Muhammad Ilyas

    2016-03-01

    Full Text Available This paper provides algorithms to estimate absolute navigation information, e.g., absolute attitude and position, by using low power, weight and volume Microelectromechanical Systems-type (MEMS sensors that are suitable for micro planetary rovers. Planetary rovers appear to be easily navigable robots due to their extreme slow speed and rotation but, unfortunately, the sensor suites available for terrestrial robots are not always available for planetary rover navigation. This makes them difficult to navigate in a completely unexplored, harsh and complex environment. Whereas the relative attitude and position can be tracked in a similar way as for ground robots, absolute navigation information, unlike in terrestrial applications, is difficult to obtain for a remote celestial body, such as Mars or the Moon. In this paper, an algorithm called the EASI algorithm (Estimation of Attitude using Sun sensor and Inclinometer is presented to estimate the absolute attitude using a MEMS-type sun sensor and inclinometer, only. Moreover, the output of the EASI algorithm is fused with MEMS gyros to produce more accurate and reliable attitude estimates. An absolute position estimation algorithm has also been presented based on these on-board sensors. Experimental results demonstrate the viability of the proposed algorithms and the sensor suite for low-cost and low-weight micro planetary rovers.

  7. On a New Near-Infrared Method to Estimate the Absolute Ages of Star Clusters: NGC 3201 as a First Test Case

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    Bono, G.; Stetson, P. B.; VandenBerg, D. A.; Calamida, A.; Dall'Ora, M.; Iannicola, G.; Amico, P.; Di Cecco, A.; Marchetti, E.; Monelli, M.; Sanna, N.; Walker, A. R.; Zoccali, M.; Buonanno, R.; Caputo, F.; Corsi, C. E.; Degl'Innocenti, S.; D'Odorico, S.; Ferraro, I.; Gilmozzi, R.; Melnick, J.; Nonino, M.; Ortolani, S.; Piersimoni, A. M.; Prada Moroni, P. G.; Pulone, L.; Romaniello, M.; Storm, J.

    2010-01-01

    We present a new method to estimate the absolute ages of stellar systems. This method is based on the difference in magnitude between the main-sequence turnoff (MSTO) and a well-defined knee located along the lower main sequence (MSK). This feature is caused by the collisionally induced absorption of molecular hydrogen, and it can easily be identified in near-infrared (NIR) and in optical-NIR color-magnitude diagrams of stellar systems. We took advantage of deep and accurate NIR images collected with the Multi-Conjugate Adaptive Optics Demonstrator temporarily available on the Very Large Telescope and of optical images collected with the Advanced Camera for Surveys Wide Field Camera on the Hubble Space Telescope and with ground-based telescopes to estimate the absolute age of the globular NGC 3201 using both the MSTO and the Δ(MSTO-MSK). We have adopted a new set of cluster isochrones, and we found that the absolute ages based on the two methods agree to within 1σ. However, the errors of the ages based on the Δ(MSTO-MSK) method are potentially more than a factor of 2 smaller, since they are not affected by uncertainties in cluster distance or reddening. Current isochrones appear to predict slightly bluer (≈0.05 mag) NIR and optical-NIR colors than observed for magnitudes fainter than the MSK. Based on near infrared observations made with ESO telescopes SOFI at NTT, La Silla; MAD at VLT Paranal, projects: 66.D-0557, 074.D-0655, ID96406, and with the Cerro Tololo Inter-American Observatory (CTIO) telescope ISPI at 4m Blanco, La Serena. Based on optical data collected with ESO telescopes and retrieved from the ESO Science Archive Facility. This research used the facilities of the Canadian Astronomy Data Centre operated by the National Research Council of Canada with the support of the Canadian Space Agency.

  8. Population-based absolute risk estimation with survey data

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    Kovalchik, Stephanie A.; Pfeiffer, Ruth M.

    2013-01-01

    Absolute risk is the probability that a cause-specific event occurs in a given time interval in the presence of competing events. We present methods to estimate population-based absolute risk from a complex survey cohort that can accommodate multiple exposure-specific competing risks. The hazard function for each event type consists of an individualized relative risk multiplied by a baseline hazard function, which is modeled nonparametrically or parametrically with a piecewise exponential model. An influence method is used to derive a Taylor-linearized variance estimate for the absolute risk estimates. We introduce novel measures of the cause-specific influences that can guide modeling choices for the competing event components of the model. To illustrate our methodology, we build and validate cause-specific absolute risk models for cardiovascular and cancer deaths using data from the National Health and Nutrition Examination Survey. Our applications demonstrate the usefulness of survey-based risk prediction models for predicting health outcomes and quantifying the potential impact of disease prevention programs at the population level. PMID:23686614

  9. Absolute and Relative Socioeconomic Health Inequalities across Age Groups.

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    van Zon, Sander K R; Bültmann, Ute; Mendes de Leon, Carlos F; Reijneveld, Sijmen A

    2015-01-01

    The magnitude of socioeconomic health inequalities differs across age groups. It is less clear whether socioeconomic health inequalities differ across age groups by other factors that are known to affect the relation between socioeconomic position and health, like the indicator of socioeconomic position, the health outcome, gender, and as to whether socioeconomic health inequalities are measured in absolute or in relative terms. The aim is to investigate whether absolute and relative socioeconomic health inequalities differ across age groups by indicator of socioeconomic position, health outcome and gender. The study sample was derived from the baseline measurement of the LifeLines Cohort Study and consisted of 95,432 participants. Socioeconomic position was measured as educational level and household income. Physical and mental health were measured with the RAND-36. Age concerned eleven 5-years age groups. Absolute inequalities were examined by comparing means. Relative inequalities were examined by comparing Gini-coefficients. Analyses were performed for both health outcomes by both educational level and household income. Analyses were performed for all age groups, and stratified by gender. Absolute and relative socioeconomic health inequalities differed across age groups by indicator of socioeconomic position, health outcome, and gender. Absolute inequalities were most pronounced for mental health by household income. They were larger in younger than older age groups. Relative inequalities were most pronounced for physical health by educational level. Gini-coefficients were largest in young age groups and smallest in older age groups. Absolute and relative socioeconomic health inequalities differed cross-sectionally across age groups by indicator of socioeconomic position, health outcome and gender. Researchers should critically consider the implications of choosing a specific age group, in addition to the indicator of socioeconomic position and health outcome

  10. The Estimation of Gestational Age at Birth in Database Studies.

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    Eberg, Maria; Platt, Robert W; Filion, Kristian B

    2017-11-01

    Studies on the safety of prenatal medication use require valid estimation of the pregnancy duration. However, gestational age is often incompletely recorded in administrative and clinical databases. Our objective was to compare different approaches to estimating the pregnancy duration. Using data from the Clinical Practice Research Datalink and Hospital Episode Statistics, we examined the following four approaches to estimating missing gestational age: (1) generalized estimating equations for longitudinal data; (2) multiple imputation; (3) estimation based on fetal birth weight and sex; and (4) conventional approaches that assigned a fixed value (39 weeks for all or 39 weeks for full term and 35 weeks for preterm). The gestational age recorded in Hospital Episode Statistics was considered the gold standard. We conducted a simulation study comparing the described approaches in terms of estimated bias and mean square error. A total of 25,929 infants from 22,774 mothers were included in our "gold standard" cohort. The smallest average absolute bias was observed for the generalized estimating equation that included birth weight, while the largest absolute bias occurred when assigning 39-week gestation to all those with missing values. The smallest mean square errors were detected with generalized estimating equations while multiple imputation had the highest mean square errors. The use of generalized estimating equations resulted in the most accurate estimation of missing gestational age when birth weight information was available. In the absence of birth weight, assignment of fixed gestational age based on term/preterm status may be the optimal approach.

  11. National cohort study of absolute risk and age-specific incidence of multiple adverse outcomes between adolescence and early middle age.

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    Mok, Pearl L H; Antonsen, Sussie; Pedersen, Carsten Bøcker; Appleby, Louis; Shaw, Jenny; Webb, Roger T

    2015-09-19

    Psychiatric illness, substance misuse, suicidality, criminality and premature death represent major public health challenges that afflict a sizeable proportion of young people. However, studies of multiple adverse outcomes in the same cohort at risk are rare. In a national Danish cohort we estimated sex- and age-specific incidence rates and absolute risks of these outcomes between adolescence and early middle age. Using interlinked registers, persons born in Denmark 1966-1996 were followed from their 15(th) until 40(th) birthday or December 2011 (N = 2,070,904). We estimated sex- and age-specific incidence rates of nine adverse outcomes, in three main categories: Premature mortality (all-causes, suicide, accident); Psychiatric morbidity (any mental illness diagnosis, suicide attempt, alcohol or drug misuse disorder); Criminality (violent offending, receiving custodial sentence, driving under influence of alcohol or drugs). Cumulative incidences were also calculated using competing risk survival analyses. For cohort members alive on their 15(th) birthday, the absolute risks of dying by age 40 were 1.99 % for males [95 % confidence interval (CI) 1.95-2.03 %] and 0.85 % for females (95 % CI 0.83-0.88 %). The risks of substance misuse and criminality were also much higher for males, especially younger males, than for females. Specifically, the risk of a first conviction for a violent offence was highest amongst males aged below 20. Females, however, were more likely than males to have a hospital-treated psychiatric disorder. By age 40, 13.25 % of females (95 % CI 13.16-13.33 %) and 9.98 % of males (95 % CI 9.91-10.06 %) had been treated. Women aged below 25 were also more likely than men to first attempt suicide, but this pattern was reversed beyond this age. The greatest gender differentials in incidence rates were in criminality outcomes. This is the first comprehensive assessment of the incidence rates and absolute risks of these multiple adverse outcomes

  12. Predicting absolute risk of type 2 diabetes using age and waist circumference values in an aboriginal Australian community.

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    Odewumi Adegbija

    Full Text Available To predict in an Australian Aboriginal community, the 10-year absolute risk of type 2 diabetes associated with waist circumference and age on baseline examination.A sample of 803 diabetes-free adults (82.3% of the age-eligible population from baseline data of participants collected from 1992 to 1998 were followed-up for up to 20 years till 2012. The Cox-proportional hazard model was used to estimate the effects of waist circumference and other risk factors, including age, smoking and alcohol consumption status, of males and females on prediction of type 2 diabetes, identified through subsequent hospitalisation data during the follow-up period. The Weibull regression model was used to calculate the absolute risk estimates of type 2 diabetes with waist circumference and age as predictors.Of 803 participants, 110 were recorded as having developed type 2 diabetes, in subsequent hospitalizations over a follow-up of 12633.4 person-years. Waist circumference was strongly associated with subsequent diagnosis of type 2 diabetes with P<0.0001 for both genders and remained statistically significant after adjusting for confounding factors. Hazard ratios of type 2 diabetes associated with 1 standard deviation increase in waist circumference were 1.7 (95%CI 1.3 to 2.2 for males and 2.1 (95%CI 1.7 to 2.6 for females. At 45 years of age with baseline waist circumference of 100 cm, a male had an absolute diabetic risk of 10.9%, while a female had a 14.3% risk of the disease.The constructed model predicts the 10-year absolute diabetes risk in an Aboriginal Australian community. It is simple and easily understood and will help identify individuals at risk of diabetes in relation to waist circumference values. Our findings on the relationship between waist circumference and diabetes on gender will be useful for clinical consultation, public health education and establishing WC cut-off points for Aboriginal Australians.

  13. Absolute magnitude estimation and relative judgement approaches to subjective workload assessment

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    Vidulich, Michael A.; Tsang, Pamela S.

    1987-01-01

    Two rating scale techniques employing an absolute magnitude estimation method, were compared to a relative judgment method for assessing subjective workload. One of the absolute estimation techniques used was an unidimensional overall workload scale and the other was the multidimensional NASA-Task Load Index technique. Thomas Saaty's Analytic Hierarchy Process was the unidimensional relative judgment method used. These techniques were used to assess the subjective workload of various single- and dual-tracking conditions. The validity of the techniques was defined as their ability to detect the same phenomena observed in the tracking performance. Reliability was assessed by calculating test-retest correlations. Within the context of the experiment, the Saaty Analytic Hierarchy Process was found to be superior in validity and reliability. These findings suggest that the relative judgment method would be an effective addition to the currently available subjective workload assessment techniques.

  14. Absolute dating of the Aegean Late Bronze Age

    International Nuclear Information System (INIS)

    Warren, P.M.

    1987-01-01

    A recent argument for raising the absolute date of the beginning of the Aegean Late Bronze (LB) Age to about 1700 B.C. is critically examined. It is argued here that: (1) the alabaster lid from Knossos did have the stratigraphical context assigned to it by Evans, in all probability Middle Minoan IIIA, c. 1650 B.C.; (2) the attempt to date the alabastron found in an early Eighteenth Dynasty context at Aniba to Late Minoan IIIA:1 is open to objections; (3) radiocarbon dates from Aegean LB I contexts are too wide in their calibrated ranges and too inconsistent both within and between site sets to offer any reliable grounds at present for raising Aegean LB I absolute chronology to 1700 B.C. Other evidence, however, suggests this period began about 1600 B.C., i.e. some fifty years earlier than the conventional date of 1550 B.C. (author)

  15. Integrated Navigation System Design for Micro Planetary Rovers: Comparison of Absolute Heading Estimation Algorithms and Nonlinear Filtering

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    Ilyas, Muhammad; Hong, Beomjin; Cho, Kuk; Baeg, Seung-Ho; Park, Sangdeok

    2016-01-01

    This paper provides algorithms to fuse relative and absolute microelectromechanical systems (MEMS) navigation sensors, suitable for micro planetary rovers, to provide a more accurate estimation of navigation information, specifically, attitude and position. Planetary rovers have extremely slow speed (~1 cm/s) and lack conventional navigation sensors/systems, hence the general methods of terrestrial navigation may not be applicable to these applications. While relative attitude and position can be tracked in a way similar to those for ground robots, absolute navigation information is hard to achieve on a remote celestial body, like Moon or Mars, in contrast to terrestrial applications. In this study, two absolute attitude estimation algorithms were developed and compared for accuracy and robustness. The estimated absolute attitude was fused with the relative attitude sensors in a framework of nonlinear filters. The nonlinear Extended Kalman filter (EKF) and Unscented Kalman filter (UKF) were compared in pursuit of better accuracy and reliability in this nonlinear estimation problem, using only on-board low cost MEMS sensors. Experimental results confirmed the viability of the proposed algorithms and the sensor suite, for low cost and low weight micro planetary rovers. It is demonstrated that integrating the relative and absolute navigation MEMS sensors reduces the navigation errors to the desired level. PMID:27223293

  16. Age Estimation in Forensic Sciences

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    Alkass, Kanar; Buchholz, Bruce A.; Ohtani, Susumu; Yamamoto, Toshiharu; Druid, Henrik; Spalding, Kirsty L.

    2010-01-01

    Age determination of unknown human bodies is important in the setting of a crime investigation or a mass disaster because the age at death, birth date, and year of death as well as gender can guide investigators to the correct identity among a large number of possible matches. Traditional morphological methods used by anthropologists to determine age are often imprecise, whereas chemical analysis of tooth dentin, such as aspartic acid racemization, has shown reproducible and more precise results. In this study, we analyzed teeth from Swedish individuals using both aspartic acid racemization and radiocarbon methodologies. The rationale behind using radiocarbon analysis is that aboveground testing of nuclear weapons during the cold war (1955–1963) caused an extreme increase in global levels of carbon-14 (14C), which has been carefully recorded over time. Forty-four teeth from 41 individuals were analyzed using aspartic acid racemization analysis of tooth crown dentin or radiocarbon analysis of enamel, and 10 of these were split and subjected to both radiocarbon and racemization analysis. Combined analysis showed that the two methods correlated well (R2 = 0.66, p Aspartic acid racemization also showed a good precision with an overall absolute error of 5.4 ± 4.2 years. Whereas radiocarbon analysis gives an estimated year of birth, racemization analysis indicates the chronological age of the individual at the time of death. We show how these methods in combination can also assist in the estimation of date of death of an unidentified victim. This strategy can be of significant assistance in forensic casework involving dead victim identification. PMID:19965905

  17. Neighbourhood socioeconomic inequalities in incidence of acute myocardial infarction: a cohort study quantifying age- and gender-specific differences in relative and absolute terms.

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    Koopman, Carla; van Oeffelen, Aloysia A M; Bots, Michiel L; Engelfriet, Peter M; Verschuren, W M Monique; van Rossem, Lenie; van Dis, Ineke; Capewell, Simon; Vaartjes, Ilonca

    2012-08-07

    Socioeconomic status has a profound effect on the risk of having a first acute myocardial infarction (AMI). Information on socioeconomic inequalities in AMI incidence across age-gender-groups is lacking. Our objective was to examine socioeconomic inequalities in the incidence of AMI considering both relative and absolute measures of risk differences, with a particular focus on age and gender. We identified all patients with a first AMI from 1997 to 2007 through linked hospital discharge and death records covering the Dutch population. Relative risks (RR) of AMI incidence were estimated by mean equivalent household income at neighbourhood-level for strata of age and gender using Poisson regression models. Socioeconomic inequalities were also shown within the stratified age-gender groups by calculating the total number of events attributable to socioeconomic disadvantage. Between 1997 and 2007, 317,564 people had a first AMI. When comparing the most deprived socioeconomic quintile with the most affluent quintile, the overall RR for AMI was 1.34 (95 % confidence interval (CI): 1.32-1.36) in men and 1.44 (95 % CI: 1.42-1.47) in women. The socioeconomic gradient decreased with age. Relative socioeconomic inequalities were most apparent in men under 35 years and in women under 65 years. The largest number of events attributable to socioeconomic inequalities was found in men aged 45-74 years and in women aged 65-84 years. The total proportion of AMIs that was attributable to socioeconomic inequalities in the Dutch population of 1997 to 2007 was 14 % in men and 18 % in women. Neighbourhood socioeconomic inequalities were observed in AMI incidence in the Netherlands, but the magnitude across age-gender groups depended on whether inequality was expressed in relative or absolute terms. Relative socioeconomic inequalities were high in young persons and women, where the absolute burden of AMI was low. Absolute socioeconomic inequalities in AMI were highest in

  18. Applying Deep Learning in Medical Images: The Case of Bone Age Estimation.

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    Lee, Jang Hyung; Kim, Kwang Gi

    2018-01-01

    A diagnostic need often arises to estimate bone age from X-ray images of the hand of a subject during the growth period. Together with measured physical height, such information may be used as indicators for the height growth prognosis of the subject. We present a way to apply the deep learning technique to medical image analysis using hand bone age estimation as an example. Age estimation was formulated as a regression problem with hand X-ray images as input and estimated age as output. A set of hand X-ray images was used to form a training set with which a regression model was trained. An image preprocessing procedure is described which reduces image variations across data instances that are unrelated to age-wise variation. The use of Caffe, a deep learning tool is demonstrated. A rather simple deep learning network was adopted and trained for tutorial purpose. A test set distinct from the training set was formed to assess the validity of the approach. The measured mean absolute difference value was 18.9 months, and the concordance correlation coefficient was 0.78. It is shown that the proposed deep learning-based neural network can be used to estimate a subject's age from hand X-ray images, which eliminates the need for tedious atlas look-ups in clinical environments and should improve the time and cost efficiency of the estimation process.

  19. Estimating absolute configurational entropies of macromolecules: the minimally coupled subspace approach.

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    Ulf Hensen

    Full Text Available We develop a general minimally coupled subspace approach (MCSA to compute absolute entropies of macromolecules, such as proteins, from computer generated canonical ensembles. Our approach overcomes limitations of current estimates such as the quasi-harmonic approximation which neglects non-linear and higher-order correlations as well as multi-minima characteristics of protein energy landscapes. Here, Full Correlation Analysis, adaptive kernel density estimation, and mutual information expansions are combined and high accuracy is demonstrated for a number of test systems ranging from alkanes to a 14 residue peptide. We further computed the configurational entropy for the full 67-residue cofactor of the TATA box binding protein illustrating that MCSA yields improved results also for large macromolecular systems.

  20. Manifold absolute pressure estimation using neural network with hybrid training algorithm.

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    Mohd Taufiq Muslim

    Full Text Available In a modern small gasoline engine fuel injection system, the load of the engine is estimated based on the measurement of the manifold absolute pressure (MAP sensor, which took place in the intake manifold. This paper present a more economical approach on estimating the MAP by using only the measurements of the throttle position and engine speed, resulting in lower implementation cost. The estimation was done via two-stage multilayer feed-forward neural network by combining Levenberg-Marquardt (LM algorithm, Bayesian Regularization (BR algorithm and Particle Swarm Optimization (PSO algorithm. Based on the results found in 20 runs, the second variant of the hybrid algorithm yields a better network performance than the first variant of hybrid algorithm, LM, LM with BR and PSO by estimating the MAP closely to the simulated MAP values. By using a valid experimental training data, the estimator network that trained with the second variant of the hybrid algorithm showed the best performance among other algorithms when used in an actual retrofit fuel injection system (RFIS. The performance of the estimator was also validated in steady-state and transient condition by showing a closer MAP estimation to the actual value.

  1. Manifold absolute pressure estimation using neural network with hybrid training algorithm.

    Science.gov (United States)

    Muslim, Mohd Taufiq; Selamat, Hazlina; Alimin, Ahmad Jais; Haniff, Mohamad Fadzli

    2017-01-01

    In a modern small gasoline engine fuel injection system, the load of the engine is estimated based on the measurement of the manifold absolute pressure (MAP) sensor, which took place in the intake manifold. This paper present a more economical approach on estimating the MAP by using only the measurements of the throttle position and engine speed, resulting in lower implementation cost. The estimation was done via two-stage multilayer feed-forward neural network by combining Levenberg-Marquardt (LM) algorithm, Bayesian Regularization (BR) algorithm and Particle Swarm Optimization (PSO) algorithm. Based on the results found in 20 runs, the second variant of the hybrid algorithm yields a better network performance than the first variant of hybrid algorithm, LM, LM with BR and PSO by estimating the MAP closely to the simulated MAP values. By using a valid experimental training data, the estimator network that trained with the second variant of the hybrid algorithm showed the best performance among other algorithms when used in an actual retrofit fuel injection system (RFIS). The performance of the estimator was also validated in steady-state and transient condition by showing a closer MAP estimation to the actual value.

  2. Neighbourhood socioeconomic inequalities in incidence of acute myocardial infarction: a cohort study quantifying age- and gender-specific differences in relative and absolute terms

    Directory of Open Access Journals (Sweden)

    Koopman Carla

    2012-08-01

    Full Text Available Abstract Background Socioeconomic status has a profound effect on the risk of having a first acute myocardial infarction (AMI. Information on socioeconomic inequalities in AMI incidence across age- gender-groups is lacking. Our objective was to examine socioeconomic inequalities in the incidence of AMI considering both relative and absolute measures of risk differences, with a particular focus on age and gender. Methods We identified all patients with a first AMI from 1997 to 2007 through linked hospital discharge and death records covering the Dutch population. Relative risks (RR of AMI incidence were estimated by mean equivalent household income at neighbourhood-level for strata of age and gender using Poisson regression models. Socioeconomic inequalities were also shown within the stratified age-gender groups by calculating the total number of events attributable to socioeconomic disadvantage. Results Between 1997 and 2007, 317,564 people had a first AMI. When comparing the most deprived socioeconomic quintile with the most affluent quintile, the overall RR for AMI was 1.34 (95 % confidence interval (CI: 1.32 – 1.36 in men and 1.44 (95 % CI: 1.42 – 1.47 in women. The socioeconomic gradient decreased with age. Relative socioeconomic inequalities were most apparent in men under 35 years and in women under 65 years. The largest number of events attributable to socioeconomic inequalities was found in men aged 45–74 years and in women aged 65–84 years. The total proportion of AMIs that was attributable to socioeconomic inequalities in the Dutch population of 1997 to 2007 was 14 % in men and 18 % in women. Conclusions Neighbourhood socioeconomic inequalities were observed in AMI incidence in the Netherlands, but the magnitude across age-gender groups depended on whether inequality was expressed in relative or absolute terms. Relative socioeconomic inequalities were high in young persons and women, where the absolute burden

  3. A Novel Method for Age Estimation in Solar-Type Stars Through GALEX FUV Magnitudes

    Science.gov (United States)

    Ho, Kelly; Subramonian, Arjun; Smith, Graeme; Shouru Shieh

    2018-01-01

    Utilizing an inverse association known to exist between Galaxy Evolution Explorer (GALEX) far ultraviolet (FUV) magnitudes and the chromospheric activity of F, G, and K dwarfs, we explored a method of age estimation in solar-type stars through GALEX FUV magnitudes. Sample solar-type star data were collected from refereed publications and filtered by B-V and absolute visual magnitude to ensure similarities in temperature and luminosity to the Sun. We determined FUV-B and calculated a residual index Q for all the stars, using the temperature-induced upper bound on FUV-B as the fiducial. Plotting current age estimates for the stars against Q, we discovered a strong and significant association between the variables. By applying a log-linear transformation to the data to produce a strong correlation between Q and loge Age, we confirmed the association between Q and age to be exponential. Thus, least-squares regression was used to generate an exponential model relating Q to age in solar-type stars, which can be used by astronomers. The Q-method of stellar age estimation is simple and more efficient than existing spectroscopic methods and has applications to galactic archaeology and stellar chemical composition analysis.

  4. Absolute Monotonicity of Functions Related To Estimates of First Eigenvalue of Laplace Operator on Riemannian Manifolds

    Directory of Open Access Journals (Sweden)

    Feng Qi

    2014-10-01

    Full Text Available The authors find the absolute monotonicity and complete monotonicity of some functions involving trigonometric functions and related to estimates the lower bounds of the first eigenvalue of Laplace operator on Riemannian manifolds.

  5. Secondary dentine as a sole parameter for age estimation: Comparison and reliability of qualitative and quantitative methods among North Western adult Indians

    Directory of Open Access Journals (Sweden)

    Jasbir Arora

    2016-06-01

    Full Text Available The indestructible nature of teeth against most of the environmental abuses makes its use in disaster victim identification (DVI. The present study has been undertaken to examine the reliability of Gustafson’s qualitative method and Kedici’s quantitative method of measuring secondary dentine for age estimation among North Western adult Indians. 196 (M = 85; F = 111 single rooted teeth were collected from the Department of Oral Health Sciences, PGIMER, Chandigarh. Ground sections were prepared and the amount of secondary dentine formed was scored qualitatively according to Gustafson’s (0–3 scoring system (method 1 and quantitatively following Kedici’s micrometric measurement method (method 2. Out of 196 teeth 180 samples (M = 80; F = 100 were found to be suitable for measuring secondary dentine following Kedici’s method. Absolute mean error of age was calculated by both methodologies. Results clearly showed that in pooled data, method 1 gave an error of ±10.4 years whereas method 2 exhibited an error of approximately ±13 years. A statistically significant difference was noted in absolute mean error of age between two methods of measuring secondary dentine for age estimation. Further, it was also revealed that teeth extracted for periodontal reasons severely decreased the accuracy of Kedici’s method however, the disease had no effect while estimating age by Gustafson’s method. No significant gender differences were noted in the absolute mean error of age by both methods which suggest that there is no need to separate data on the basis of gender.

  6. Forensic Age Estimation of Chinese Malaysian Adults by Evaluating Occlusal Tooth Wear Using Modified Kim’s Index

    Directory of Open Access Journals (Sweden)

    Chai Kit Lu

    2017-01-01

    Full Text Available Background and Objective. Evaluation of dental attrition is an easy and relatively accurate approach to estimating the age of an adult either ante- or postmortem for some specific population. Dental attrition represents a progressive physiological age change that can be measured using variety of indices to aid as an adjunct in forensic age estimation. Some of the previously proposed indices have their own practical limitations. This paper focuses on using modified Kim’s criteria to score dental attrition to estimate the age of Chinese Malaysian adults and validate it. Methodology. Tooth wear was evaluated on 190 dental models of Chinese Malaysian adults (age range: 20–60 years using modified Kim’s index to custom-derive a population specific linear equation. The same equation was validated further on new 60 dental casts. Results and Conclusion. Regression analysis revealed good correlation between age and teeth wear and lower standard error of estimate. Test of regression on a test sample (n=30 pairs, age range: 20–60 years showed insignificant difference between predicted versus the actual age with statistically acceptable mean absolute difference. These data suggest that modified Kim’s index can be used effectively in forensic age estimation.

  7. Coronary calcium predicts events better with absolute calcium scores than age-sex-race/ethnicity percentiles: MESA (Multi-Ethnic Study of Atherosclerosis).

    Science.gov (United States)

    Budoff, Matthew J; Nasir, Khurram; McClelland, Robyn L; Detrano, Robert; Wong, Nathan; Blumenthal, Roger S; Kondos, George; Kronmal, Richard A

    2009-01-27

    In this study, we aimed to establish whether age-sex-specific percentiles of coronary artery calcium (CAC) predict cardiovascular outcomes better than the actual (absolute) CAC score. The presence and extent of CAC correlates with the overall magnitude of coronary atherosclerotic plaque burden and with the development of subsequent coronary events. MESA (Multi-Ethnic Study of Atherosclerosis) is a prospective cohort study of 6,814 asymptomatic participants followed for coronary heart disease (CHD) events including myocardial infarction, angina, resuscitated cardiac arrest, or CHD death. Time to incident CHD was modeled with Cox regression, and we compared models with percentiles based on age, sex, and/or race/ethnicity to categories commonly used (0, 1 to 100, 101 to 400, 400+ Agatston units). There were 163 (2.4%) incident CHD events (median follow-up 3.75 years). Expressing CAC in terms of age- and sex-specific percentiles had significantly lower area under the receiver-operating characteristic curve (AUC) than when using absolute scores (women: AUC 0.73 versus 0.76, p = 0.044; men: AUC 0.73 versus 0.77, p better model fit with the overall score. Both methods robustly predicted events (>90th percentile associated with a hazard ratio [HR] of 16.4, 95% confidence interval [CI]: 9.30 to 28.9, and score >400 associated with HR of 20.6, 95% CI: 11.8 to 36.0). Within groups based on age-, sex-, and race/ethnicity-specific percentiles there remains a clear trend of increasing risk across levels of the absolute CAC groups. In contrast, once absolute CAC category is fixed, there is no increasing trend across levels of age-, sex-, and race/ethnicity-specific categories. Patients with low absolute scores are low-risk, regardless of age-, sex-, and race/ethnicity-specific percentile rank. Persons with an absolute CAC score of >400 are high risk, regardless of percentile rank. Using absolute CAC in standard groups performed better than age-, sex-, and race

  8. Performance of models for estimating absolute risk difference in multicenter trials with binary outcome

    Directory of Open Access Journals (Sweden)

    Claudia Pedroza

    2016-08-01

    Full Text Available Abstract Background Reporting of absolute risk difference (RD is recommended for clinical and epidemiological prospective studies. In analyses of multicenter studies, adjustment for center is necessary when randomization is stratified by center or when there is large variation in patients outcomes across centers. While regression methods are used to estimate RD adjusted for baseline predictors and clustering, no formal evaluation of their performance has been previously conducted. Methods We performed a simulation study to evaluate 6 regression methods fitted under a generalized estimating equation framework: binomial identity, Poisson identity, Normal identity, log binomial, log Poisson, and logistic regression model. We compared the model estimates to unadjusted estimates. We varied the true response function (identity or log, number of subjects per center, true risk difference, control outcome rate, effect of baseline predictor, and intracenter correlation. We compared the models in terms of convergence, absolute bias and coverage of 95 % confidence intervals for RD. Results The 6 models performed very similar to each other for the majority of scenarios. However, the log binomial model did not converge for a large portion of the scenarios including a baseline predictor. In scenarios with outcome rate close to the parameter boundary, the binomial and Poisson identity models had the best performance, but differences from other models were negligible. The unadjusted method introduced little bias to the RD estimates, but its coverage was larger than the nominal value in some scenarios with an identity response. Under the log response, coverage from the unadjusted method was well below the nominal value (<80 % for some scenarios. Conclusions We recommend the use of a binomial or Poisson GEE model with identity link to estimate RD for correlated binary outcome data. If these models fail to run, then either a logistic regression, log Poisson

  9. Danish Towns during Absolutism

    DEFF Research Database (Denmark)

    This anthology, No. 4 in the Danish Urban Studies Series, presents in English recent significant research on Denmark's urban development during the Age of Absolutism, 1660-1848, and features 13 articles written by leading Danish urban historians. The years of Absolutism were marked by a general...

  10. Age estimation in the living

    DEFF Research Database (Denmark)

    Tangmose, Sara; Thevissen, Patrick; Lynnerup, Niels

    2015-01-01

    A radiographic assessment of third molar development is essential for differentiating between juveniles and adolescents in forensic age estimations. As the developmental stages of third molars are highly correlated, age estimates based on a combination of a full set of third molar scores...... are statistically complicated. Transition analysis (TA) is a statistical method developed for estimating age at death in skeletons, which combines several correlated developmental traits into one age estimate including a 95% prediction interval. The aim of this study was to evaluate the performance of TA...... in the living on a full set of third molar scores. A cross sectional sample of 854 panoramic radiographs, homogenously distributed by sex and age (15.0-24.0 years), were randomly split in two; a reference sample for obtaining age estimates including a 95% prediction interval according to TA; and a validation...

  11. Optimal dental age estimation practice in United Arab Emirates' children.

    Science.gov (United States)

    Altalie, Salem; Thevissen, Patrick; Fieuws, Steffen; Willems, Guy

    2014-03-01

    The aim of the study was to detect whether the Willems model, developed on a Belgian reference sample, can be used for age estimations in United Arab Emirates (UAE) children. Furthermore, it was verified that if added third molars development information in children provided more accurate age predictions. On 1900 panoramic radiographs, the development of left mandibular permanent teeth (PT) and third molars (TM) was registered according the Demirjian and the Kohler technique, respectively. The PT data were used to verify the Willems model and to develop a UAE model and to verify it. Multiple regression models with PT, TM, and PT + TM scores as independent and age as dependent factor were developed. Comparing the verified Willems- and the UAE model revealed differences in mean error of -0.01 year, mean absolute error of 0.01 year and root mean squared error of 0.90 year. Neglectable overall decrease in RMSE was detected combining PM and TM developmental information. © 2013 American Academy of Forensic Sciences.

  12. An Inverse Relative Age Effect in Male Alpine Skiers at the Absolute Top Level.

    Science.gov (United States)

    Bjerke, Øyvind; Pedersen, Arve Vorland; Aune, Tore K; Lorås, Håvard

    2017-01-01

    The Relative Age Effect (RAE) can be described as the advantage of being born early after a certain cut-off date within a group of selection. The effect has been found across a wide range of sports and is particularly evident in pre-elite sports and team sports with a high selection pressure. At the absolute top level in team elite sports, the advantage of being relatively older has been reported to disappear, and even reverse, so that the relatively younger athletes are advantaged. In order to further examine such a reversal of the RAE, we investigated the performance of the overall top 50 skiers each year in the alpine World Cup, over a period of 20 years, among men ( N = 234) and women ( N = 235). The data indicated that the relatively younger male athletes at the absolute top level had accumulated, on average, more World Cup points compared to the relatively older skiers. No such effect was observed among the female skiers. This finding suggest the existence of a reversed relative age effect in male elite alpine skiing.

  13. An Inverse Relative Age Effect in Male Alpine Skiers at the Absolute Top Level

    Directory of Open Access Journals (Sweden)

    Øyvind Bjerke

    2017-07-01

    Full Text Available The Relative Age Effect (RAE can be described as the advantage of being born early after a certain cut-off date within a group of selection. The effect has been found across a wide range of sports and is particularly evident in pre-elite sports and team sports with a high selection pressure. At the absolute top level in team elite sports, the advantage of being relatively older has been reported to disappear, and even reverse, so that the relatively younger athletes are advantaged. In order to further examine such a reversal of the RAE, we investigated the performance of the overall top 50 skiers each year in the alpine World Cup, over a period of 20 years, among men (N = 234 and women (N = 235. The data indicated that the relatively younger male athletes at the absolute top level had accumulated, on average, more World Cup points compared to the relatively older skiers. No such effect was observed among the female skiers. This finding suggest the existence of a reversed relative age effect in male elite alpine skiing.

  14. Reliability of third molar development for age estimation in Gujarati population: A comparative study.

    Science.gov (United States)

    Gandhi, Neha; Jain, Sandeep; Kumar, Manish; Rupakar, Pratik; Choyal, Kanaram; Prajapati, Seema

    2015-01-01

    Age assessment may be a crucial step in postmortem profiling leading to confirmative identification. In children, Demirjian's method based on eight developmental stages was developed to determine maturity scores as a function of age and polynomial functions to determine age as a function of score. Of this study was to evaluate the reliability of age estimation using Demirjian's eight teeth method following the French maturity scores and Indian-specific formula from developmental stages of third molar with the help of orthopantomograms using the Demirjian method. Dental panoramic tomograms from 30 subjects each of known chronological age and sex were collected and were evaluated according to Demirjian's criteria. Age calculations were performed using Demirjian's formula and Indian formula. Statistical analysis used was Chi-square test and ANOVA test and the P values obtained were statistically significant. There was an average underestimation of age with both Indian and Demirjian's formulas. The mean absolute error was lower using Indian formula hence it can be applied for age estimation in present Gujarati population. Also, females were ahead of achieving dental maturity than males thus completion of dental development is attained earlier in females. Greater accuracy can be obtained if population-specific formulas considering the ethnic and environmental variation are derived performing the regression analysis.

  15. Infant bone age estimation based on fibular shaft length: model development and clinical validation

    International Nuclear Information System (INIS)

    Tsai, Andy; Stamoulis, Catherine; Bixby, Sarah D.; Breen, Micheal A.; Connolly, Susan A.; Kleinman, Paul K.

    2016-01-01

    Bone age in infants (<1 year old) is generally estimated using hand/wrist or knee radiographs, or by counting ossification centers. The accuracy and reproducibility of these techniques are largely unknown. To develop and validate an infant bone age estimation technique using fibular shaft length and compare it to conventional methods. We retrospectively reviewed negative skeletal surveys of 247 term-born low-risk-of-abuse infants (no persistent child protection team concerns) from July 2005 to February 2013, and randomized them into two datasets: (1) model development (n = 123) and (2) model testing (n = 124). Three pediatric radiologists measured all fibular shaft lengths. An ordinary linear regression model was fitted to dataset 1, and the model was evaluated using dataset 2. Readers also estimated infant bone ages in dataset 2 using (1) the hemiskeleton method of Sontag, (2) the hemiskeleton method of Elgenmark, (3) the hand/wrist atlas of Greulich and Pyle, and (4) the knee atlas of Pyle and Hoerr. For validation, we selected lower-extremity radiographs of 114 normal infants with no suspicion of abuse. Readers measured the fibulas and also estimated bone ages using the knee atlas. Bone age estimates from the proposed method were compared to the other methods. The proposed method outperformed all other methods in accuracy and reproducibility. Its accuracy was similar for the testing and validating datasets, with root-mean-square error of 36 days and 37 days; mean absolute error of 28 days and 31 days; and error variability of 22 days and 20 days, respectively. This study provides strong support for an infant bone age estimation technique based on fibular shaft length as a more accurate alternative to conventional methods. (orig.)

  16. Infant bone age estimation based on fibular shaft length: model development and clinical validation

    Energy Technology Data Exchange (ETDEWEB)

    Tsai, Andy; Stamoulis, Catherine; Bixby, Sarah D.; Breen, Micheal A.; Connolly, Susan A.; Kleinman, Paul K. [Boston Children' s Hospital, Harvard Medical School, Department of Radiology, Boston, MA (United States)

    2016-03-15

    Bone age in infants (<1 year old) is generally estimated using hand/wrist or knee radiographs, or by counting ossification centers. The accuracy and reproducibility of these techniques are largely unknown. To develop and validate an infant bone age estimation technique using fibular shaft length and compare it to conventional methods. We retrospectively reviewed negative skeletal surveys of 247 term-born low-risk-of-abuse infants (no persistent child protection team concerns) from July 2005 to February 2013, and randomized them into two datasets: (1) model development (n = 123) and (2) model testing (n = 124). Three pediatric radiologists measured all fibular shaft lengths. An ordinary linear regression model was fitted to dataset 1, and the model was evaluated using dataset 2. Readers also estimated infant bone ages in dataset 2 using (1) the hemiskeleton method of Sontag, (2) the hemiskeleton method of Elgenmark, (3) the hand/wrist atlas of Greulich and Pyle, and (4) the knee atlas of Pyle and Hoerr. For validation, we selected lower-extremity radiographs of 114 normal infants with no suspicion of abuse. Readers measured the fibulas and also estimated bone ages using the knee atlas. Bone age estimates from the proposed method were compared to the other methods. The proposed method outperformed all other methods in accuracy and reproducibility. Its accuracy was similar for the testing and validating datasets, with root-mean-square error of 36 days and 37 days; mean absolute error of 28 days and 31 days; and error variability of 22 days and 20 days, respectively. This study provides strong support for an infant bone age estimation technique based on fibular shaft length as a more accurate alternative to conventional methods. (orig.)

  17. The Impact of Strategy Instruction and Timing of Estimates on Low and High Working-Memory Capacity Readers' Absolute Monitoring Accuracy

    Science.gov (United States)

    Linderholm, Tracy; Zhao, Qin

    2008-01-01

    Working-memory capacity, strategy instruction, and timing of estimates were investigated for their effects on absolute monitoring accuracy, which is the difference between estimated and actual reading comprehension test performance. Participants read two expository texts under one of two randomly assigned reading strategy instruction conditions…

  18. Combining wrist age and third molars in forensic age estimation: how to calculate the joint age estimate and its error rate in age diagnostics.

    Science.gov (United States)

    Gelbrich, Bianca; Frerking, Carolin; Weiss, Sandra; Schwerdt, Sebastian; Stellzig-Eisenhauer, Angelika; Tausche, Eve; Gelbrich, Götz

    2015-01-01

    Forensic age estimation in living adolescents is based on several methods, e.g. the assessment of skeletal and dental maturation. Combination of several methods is mandatory, since age estimates from a single method are too imprecise due to biological variability. The correlation of the errors of the methods being combined must be known to calculate the precision of combined age estimates. To examine the correlation of the errors of the hand and the third molar method and to demonstrate how to calculate the combined age estimate. Clinical routine radiographs of the hand and dental panoramic images of 383 patients (aged 7.8-19.1 years, 56% female) were assessed. Lack of correlation (r = -0.024, 95% CI = -0.124 to + 0.076, p = 0.64) allows calculating the combined age estimate as the weighted average of the estimates from hand bones and third molars. Combination improved the standard deviations of errors (hand = 0.97, teeth = 1.35 years) to 0.79 years. Uncorrelated errors of the age estimates obtained from both methods allow straightforward determination of the common estimate and its variance. This is also possible when reference data for the hand and the third molar method are established independently from each other, using different samples.

  19. Age estimation in forensic sciences: Application of combined aspartic acid racemization and radiocarbon analysis

    Energy Technology Data Exchange (ETDEWEB)

    Alkass, K; Buchholz, B A; Ohtani, S; Yamamoto, T; Druid, H; Spalding, S L

    2009-11-02

    Age determination of unknown human bodies is important in the setting of a crime investigation or a mass disaster, since the age at death, birth date and year of death, as well as gender, can guide investigators to the correct identity among a large number of possible matches. Traditional morphological methods used by anthropologists to determine age are often imprecise, whereas chemical analysis of tooth dentin, such as aspartic acid racemization has shown reproducible and more precise results. In this paper we analyze teeth from Swedish individuals using both aspartic acid racemization and radiocarbon methodologies. The rationale behind using radiocarbon analysis is that above-ground testing of nuclear weapons during the cold war (1955-1963) caused an extreme increase in global levels of carbon-14 ({sup 14}C) which have been carefully recorded over time. Forty-four teeth from 41 individuals were analyzed using aspartic acid racemization analysis of tooth crown dentin or radiocarbon analysis of enamel and ten of these were split and subjected to both radiocarbon and racemization analysis. Combined analysis showed that the two methods correlated well (R2=0.66, p < 0.05). Radiocarbon analysis showed an excellent precision with an overall absolute error of 0.6 {+-} 04 years. Aspartic acid racemization also showed a good precision with an overall absolute error of 5.4 {+-} 4.2 years. Whereas radiocarbon analysis gives an estimated year of birth, racemization analysis indicates the chronological age of the individual at the time of death. We show how these methods in combination can also assist in the estimation of date of death of an unidentified victim. This strategy can be of significant assistance in forensic casework involving dead victim identification.

  20. A developmental study of latent absolute pitch memory.

    Science.gov (United States)

    Jakubowski, Kelly; Müllensiefen, Daniel; Stewart, Lauren

    2017-03-01

    The ability to recall the absolute pitch level of familiar music (latent absolute pitch memory) is widespread in adults, in contrast to the rare ability to label single pitches without a reference tone (overt absolute pitch memory). The present research investigated the developmental profile of latent absolute pitch (AP) memory and explored individual differences related to this ability. In two experiments, 288 children from 4 to12 years of age performed significantly above chance at recognizing the absolute pitch level of familiar melodies. No age-related improvement or decline, nor effects of musical training, gender, or familiarity with the stimuli were found in regard to latent AP task performance. These findings suggest that latent AP memory is a stable ability that is developed from as early as age 4 and persists into adulthood.

  1. A self-consistent, absolute isochronal age scale for young moving groups in the solar neighbourhood

    Science.gov (United States)

    Bell, Cameron P. M.; Mamajek, Eric E.; Naylor, Tim

    2015-11-01

    We present a self-consistent, absolute isochronal age scale for young ( ≲ 200 Myr), nearby ( ≲ 100 pc) moving groups in the solar neighbourhood based on homogeneous fitting of semi-empirical pre-main-sequence model isochrones using the τ2 maximum-likelihood fitting statistic of Naylor & Jeffries in the MV, V - J colour-magnitude diagram. The final adopted ages for the groups are as follows: 149^{+51}_{-19} {Myr} for the AB Dor moving group, 24 ± 3 Myr for the β Pic moving group (BPMG), 45^{+11}_{-7} {Myr} for the Carina association, 42^{+6}_{-4} {Myr} for the Columba association, 11 ± 3 Myr for the η Cha cluster, 45 ± 4 Myr for the Tucana-Horologium moving group (Tuc-Hor), 10 ± 3 Myr for the TW Hya association and 22^{+4}_{-3} {Myr} for the 32 Ori group. At this stage we are uncomfortable assigning a final, unambiguous age to the Argus association as our membership list for the association appears to suffer from a high level of contamination, and therefore it remains unclear whether these stars represent a single population of coeval stars. Our isochronal ages for both the BPMG and Tuc-Hor are consistent with recent lithium depletion boundary (LDB) ages, which unlike isochronal ages, are relatively insensitive to the choice of low-mass evolutionary models. This consistency between the isochronal and LDB ages instils confidence that our self-consistent, absolute age scale for young, nearby moving groups is robust, and hence we suggest that these ages be adopted for future studies of these groups. Software implementing the methods described in this study is available from http://www.astro.ex.ac.uk/people/timn/tau-squared/.

  2. Bayesian estimation of isotopic age differences

    International Nuclear Information System (INIS)

    Curl, R.L.

    1988-01-01

    Isotopic dating is subject to uncertainties arising from counting statistics and experimental errors. These uncertainties are additive when an isotopic age difference is calculated. If large, they can lead to no significant age difference by classical statistics. In many cases, relative ages are known because of stratigraphic order or other clues. Such information can be used to establish a Bayes estimate of age difference which will include prior knowledge of age order. Age measurement errors are assumed to be log-normal and a noninformative but constrained bivariate prior for two true ages in known order is adopted. True-age ratio is distributed as a truncated log-normal variate. Its expected value gives an age-ratio estimate, and its variance provides credible intervals. Bayesian estimates of ages are different and in correct order even if measured ages are identical or reversed in order. For example, age measurements on two samples might both yield 100 ka with coefficients of variation of 0.2. Bayesian estimates are 22.7 ka for age difference with a 75% credible interval of [4.4, 43.7] ka

  3. Dental age estimation in Japanese individuals combining permanent teeth and third molars.

    Science.gov (United States)

    Ramanan, Namratha; Thevissen, Patrick; Fleuws, Steffen; Willems, G

    2012-12-01

    The study aim was, firstly, to verify the Willems et al. model on a Japanese reference sample. Secondly to develop a Japanese reference model based on the Willems et al. method and to verify it. Thirdly to analyze the age prediction performance adding tooth development information of third molars to permanent teeth. Retrospectively 1877 panoramic radiographs were selected in the age range between 1 and 23 years (1248 children, 629 sub-adults). Dental development was registered applying Demirjian 's stages of the mandibular left permanent teeth in children and Köhler stages on the third molars. The children's data were, firstly, used to validate the Willems et al. model (developed a Belgian reference sample), secondly, split ino a training and a test sample. On the training sample a Japanese reference model was developed based on the Willems method. The developed model and the Willems et al; model were verified on the test sample. Regression analysis was used to detect the age prediction performance adding third molar scores to permanent tooth scores. The validated Willems et al. model provided a mean absolute error of 0.85 and 0.75 years in females and males, respectively. The mean absolute error in the verified Willems et al. and the developed Japanese reference model was 0.85, 0.77 and 0.79, 0.75 years in females and males, respectively. On average a negligible change in root mean square error values was detected adding third molar scores to permanent teeth scores. The Belgian sample could be used as a reference model to estimate the age of the Japanese individuals. Combining information from the third molars and permanent teeth was not providing clinically significant improvement of age predictions based on permanent teeth information alone.

  4. Forensic age estimation based on development of third molars: a staging technique for magnetic resonance imaging.

    Science.gov (United States)

    De Tobel, J; Phlypo, I; Fieuws, S; Politis, C; Verstraete, K L; Thevissen, P W

    2017-12-01

    The development of third molars can be evaluated with medical imaging to estimate age in subadults. The appearance of third molars on magnetic resonance imaging (MRI) differs greatly from that on radiographs. Therefore a specific staging technique is necessary to classify third molar development on MRI and to apply it for age estimation. To develop a specific staging technique to register third molar development on MRI and to evaluate its performance for age estimation in subadults. Using 3T MRI in three planes, all third molars were evaluated in 309 healthy Caucasian participants from 14 to 26 years old. According to the appearance of the developing third molars on MRI, descriptive criteria and schematic representations were established to define a specific staging technique. Two observers, with different levels of experience, staged all third molars independently with the developed technique. Intra- and inter-observer agreement were calculated. The data were imported in a Bayesian model for age estimation as described by Fieuws et al. (2016). This approach adequately handles correlation between age indicators and missing age indicators. It was used to calculate a point estimate and a prediction interval of the estimated age. Observed age minus predicted age was calculated, reflecting the error of the estimate. One-hundred and sixty-six third molars were agenetic. Five percent (51/1096) of upper third molars and 7% (70/1044) of lower third molars were not assessable. Kappa for inter-observer agreement ranged from 0.76 to 0.80. For intra-observer agreement kappa ranged from 0.80 to 0.89. However, two stage differences between observers or between staging sessions occurred in up to 2.2% (20/899) of assessments, probably due to a learning effect. Using the Bayesian model for age estimation, a mean absolute error of 2.0 years in females and 1.7 years in males was obtained. Root mean squared error equalled 2.38 years and 2.06 years respectively. The performance to

  5. Relative and absolute risk in epidemiology and health physics

    International Nuclear Information System (INIS)

    Goldsmith, R.; Peterson, H.T. Jr.

    1983-01-01

    The health risk from ionizing radiation commonly is expressed in two forms: (1) the relative risk, which is the percentage increase in natural disease rate and (2) the absolute or attributable risk which represents the difference between the natural rate and the rate associated with the agent in question. Relative risk estimates for ionizing radiation generally are higher than those expressed as the absolute risk. This raises the question of which risk estimator is the most appropriate under different conditions. The absolute risk has generally been used for radiation risk assessment, although mathematical combinations such as the arithmetic or geometric mean of both the absolute and relative risks, have also been used. Combinations of the two risk estimators are not valid because the absolute and relative risk are not independent variables. Both human epidemiologic studies and animal experimental data can be found to illustrate the functional relationship between the natural cancer risk and the risk associated with radiation. This implies that the radiation risk estimate derived from one population may not be appropriate for predictions in another population, unless it is adjusted for the difference in the natural disease incidence between the two populations

  6. Adequacy of relative and absolute risk models for lifetime risk estimate of radiation-induced cancer

    International Nuclear Information System (INIS)

    McBride, M.; Coldman, A.J.

    1988-03-01

    This report examines the applicability of the relative (multiplicative) and absolute (additive) models in predicting lifetime risk of radiation-induced cancer. A review of the epidemiologic literature, and a discussion of the mathematical models of carcinogenesis and their relationship to these models of lifetime risk, are included. Based on the available data, the relative risk model for the estimation of lifetime risk is preferred for non-sex-specific epithelial tumours. However, because of lack of knowledge concerning other determinants of radiation risk and of background incidence rates, considerable uncertainty in modelling lifetime risk still exists. Therefore, it is essential that follow-up of exposed cohorts be continued so that population-based estimates of lifetime risk are available

  7. A self-consistent, absolute isochronal age scale for young moving groups in the solar neighbourhood

    OpenAIRE

    Bell, Cameron P. M.; Mamajek, Eric E.; Naylor, Tim

    2015-01-01

    We present a self-consistent, absolute isochronal age scale for young (< 200 Myr), nearby (< 100 pc) moving groups in the solar neighbourhood based on homogeneous fitting of semi-empirical pre-main-sequence model isochrones using the tau^2 maximum-likelihood fitting statistic of Naylor & Jeffries in the M_V, V-J colour-magnitude diagram. The final adopted ages for the groups are: 149+51-19 Myr for the AB Dor moving group, 24+/-3 Myr for the {\\beta} Pic moving group (BPMG), 45+11-7 Myr for the...

  8. Age estimation based on pulp chamber volume of first molars from cone-beam computed tomography images.

    Science.gov (United States)

    Ge, Zhi-pu; Ma, Ruo-han; Li, Gang; Zhang, Ji-zong; Ma, Xu-chen

    2015-08-01

    To establish a method that can be used for human age estimation on the basis of pulp chamber volume of first molars and to identify whether the method is good enough for age estimation in real human cases. CBCT images of 373 maxillary first molars and 372 mandibular first molars were collected to establish the mathematical model from 190 female and 213 male patients whose age between 12 and 69 years old. The inclusion criteria of the first molars were: no caries, no excessive tooth wear, no dental restorations, no artifacts due to metal restorative materials present in adjacent teeth, and no pulpal calcification. All the CBCT images were acquired with a CBCT unit NewTom VG (Quantitative Radiology, Verona, Italy) and reconstructed with a voxel-size of 0.15mm. The images were subsequently exported as DICOM data sets and imported into an open source 3D image semi-automatic segmenting and voxel-counting software ITK-SNAP 2.4 for the calculation of pulp chamber volumes. A logarithmic regression analysis was conducted with age as dependent variable and pulp chamber volume as independent variables to establish a mathematical model for the human age estimation. To identify the precision and accuracy of the model for human age estimation, another 104 maxillary first molars and 103 mandibular first molars from 55 female and 57 male patients whose age between 12 and 67 years old were collected, too. Mean absolute error and root mean square error between the actual age and estimated age were used to determine the precision and accuracy of the mathematical model. The study was approved by the Institutional Review Board of Peking University School and Hospital of Stomatology. A mathematical model was suggested for: AGE=117.691-26.442×ln (pulp chamber volume). The regression was statistically significant (p=0.000volume of first molar is a useful index for the estimation of human age with reasonable precision and accuracy. Copyright © 2015 Elsevier Ireland Ltd. All rights

  9. Molecular pathology and age estimation.

    Science.gov (United States)

    Meissner, Christoph; Ritz-Timme, Stefanie

    2010-12-15

    Over the course of our lifetime a stochastic process leads to gradual alterations of biomolecules on the molecular level, a process that is called ageing. Important changes are observed on the DNA-level as well as on the protein level and are the cause and/or consequence of our 'molecular clock', influenced by genetic as well as environmental parameters. These alterations on the molecular level may aid in forensic medicine to estimate the age of a living person, a dead body or even skeletal remains for identification purposes. Four such important alterations have become the focus of molecular age estimation in the forensic community over the last two decades. The age-dependent accumulation of the 4977bp deletion of mitochondrial DNA and the attrition of telomeres along with ageing are two important processes at the DNA-level. Among a variety of protein alterations, the racemisation of aspartic acid and advanced glycation endproducs have already been tested for forensic applications. At the moment the racemisation of aspartic acid represents the pinnacle of molecular age estimation for three reasons: an excellent standardization of sampling and methods, an evaluation of different variables in many published studies and highest accuracy of results. The three other mentioned alterations often lack standardized procedures, published data are sparse and often have the character of pilot studies. Nevertheless it is important to evaluate molecular methods for their suitability in forensic age estimation, because supplementary methods will help to extend and refine accuracy and reliability of such estimates. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  10. Differences between Estimation and Real Performance in School-Age Children: Fundamental Movement Skills

    Directory of Open Access Journals (Sweden)

    Gabriela Almeida

    2016-01-01

    Full Text Available Observations in studies of estimation compared to actual performance in motor skills revealed that children are not always accurate and have a tendency to overestimate the maximum distance at which an action can be performed. The relationship between estimated and real motor competences was analyzed for several tasks: standing long jump (SLJ, throwing and kicking, and walking backwards (WB on a balance beam. Children were asked to predict their maximum distance prior to performing those tasks. Participants were 303 children (160 boys, which were between 6 and 10 years of age (M=8.63, SD=1.16. Children’s estimations were compared with their real performance to determine their accuracy. Absolute error (|real performance − estimation| and error tendency, that is, the direction of the error (overestimation, accuracy, and underestimation bias, were calculated. Children had a tendency to overestimate their performance and were more conservative in the WB task, a noncommon action. In general, it is possible to conclude that children, in the studied age span, tend to overestimate their performance, particularly in familiar skills. This fact may be determinant to the development of their motor competences, since they are more likely to engage and persist in motor tasks, but it might also be a problem in terms of child safety because it could increase the occurrence of unintended injuries.

  11. Absolute determination of the deuterium content of heavy water, measurement of absolute density

    International Nuclear Information System (INIS)

    Ceccaldi, M.; Riedinger, M.; Menache, M.

    1975-01-01

    The absolute density of two heavy water samples rich in deuterium (with a grade higher than 99.9%) was determined with the hydrostatic method. The exact isotopic composition of this water (hydrogen and oxygen isotopes) was very carefully studied. A theoretical estimate enabled us to get the absolute density value of isotopically pure D 2 16 O. This value was found to be 1104.750 kg.m -3 at t 68 =22.3 0 C and under the pressure of one atmosphere. (orig.) [de

  12. Indirectly estimated absolute lung cancer mortality rates by smoking status and histological type based on a systematic review

    International Nuclear Information System (INIS)

    Lee, Peter N; Forey, Barbara A

    2013-01-01

    National smoking-specific lung cancer mortality rates are unavailable, and studies presenting estimates are limited, particularly by histology. This hinders interpretation. We attempted to rectify this by deriving estimates indirectly, combining data from national rates and epidemiological studies. We estimated study-specific absolute mortality rates and variances by histology and smoking habit (never/ever/current/former) based on relative risk estimates derived from studies published in the 20 th century, coupled with WHO mortality data for age 70–74 for the relevant country and period. Studies with populations grossly unrepresentative nationally were excluded. 70–74 was chosen based on analyses of large cohort studies presenting rates by smoking and age. Variations by sex, period and region were assessed by meta-analysis and meta-regression. 148 studies provided estimates (Europe 59, America 54, China 22, other Asia 13), 54 providing estimates by histology (squamous cell carcinoma, adenocarcinoma). For all smoking habits and lung cancer types, mortality rates were higher in males, the excess less evident for never smokers. Never smoker rates were clearly highest in China, and showed some increasing time trend, particularly for adenocarcinoma. Ever smoker rates were higher in parts of Europe and America than in China, with the time trend very clear, especially for adenocarcinoma. Variations by time trend and continent were clear for current smokers (rates being higher in Europe and America than Asia), but less clear for former smokers. Models involving continent and trend explained much variability, but non-linearity was sometimes seen (with rates lower in 1991–99 than 1981–90), and there was regional variation within continent (with rates in Europe often high in UK and low in Scandinavia, and higher in North than South America). The indirect method may be questioned, because of variations in definition of smoking and lung cancer type in the

  13. Indirectly estimated absolute lung cancer mortality rates by smoking status and histological type based on a systematic review

    Science.gov (United States)

    2013-01-01

    Background National smoking-specific lung cancer mortality rates are unavailable, and studies presenting estimates are limited, particularly by histology. This hinders interpretation. We attempted to rectify this by deriving estimates indirectly, combining data from national rates and epidemiological studies. Methods We estimated study-specific absolute mortality rates and variances by histology and smoking habit (never/ever/current/former) based on relative risk estimates derived from studies published in the 20th century, coupled with WHO mortality data for age 70–74 for the relevant country and period. Studies with populations grossly unrepresentative nationally were excluded. 70–74 was chosen based on analyses of large cohort studies presenting rates by smoking and age. Variations by sex, period and region were assessed by meta-analysis and meta-regression. Results 148 studies provided estimates (Europe 59, America 54, China 22, other Asia 13), 54 providing estimates by histology (squamous cell carcinoma, adenocarcinoma). For all smoking habits and lung cancer types, mortality rates were higher in males, the excess less evident for never smokers. Never smoker rates were clearly highest in China, and showed some increasing time trend, particularly for adenocarcinoma. Ever smoker rates were higher in parts of Europe and America than in China, with the time trend very clear, especially for adenocarcinoma. Variations by time trend and continent were clear for current smokers (rates being higher in Europe and America than Asia), but less clear for former smokers. Models involving continent and trend explained much variability, but non-linearity was sometimes seen (with rates lower in 1991–99 than 1981–90), and there was regional variation within continent (with rates in Europe often high in UK and low in Scandinavia, and higher in North than South America). Conclusions The indirect method may be questioned, because of variations in definition of smoking and

  14. Uranium isotope ratios of Muonionalusta troilite and complications for the absolute age of the IVA iron meteorite core

    Science.gov (United States)

    Brennecka, Gregory A.; Amelin, Yuri; Kleine, Thorsten

    2018-05-01

    The crystallization ages of planetary crustal material (given by basaltic meteorites) and planetary cores (given by iron meteorites) provide fiducial marks for the progress of planetary formation, and thus, the absolute ages of these objects fundamentally direct our knowledge and understanding of planet formation and evolution. The lone precise absolute age of planetary core material was previously obtained on troilite inclusions from the IVA iron meteorite Muonionalusta. This previously reported Pb-Pb age of 4565.3 ± 0.1 Ma-assuming a 238U/235U =137.88-only post-dated the start of the Solar System by approximately 2-3 million years, and mandated fast cooling of planetary core material. Since an accurate Pb-Pb age requires a known 238U/235U of the sample, we have measured both 238U/235U and Pb isotopic compositions of troilite inclusions from Muonionalusta. The measured 238U/235U of the samples range from ∼137.84 to as low as ∼137.22, however based on Pb and U systematics, terrestrial contamination appears pervasive and has affected samples to various extents for Pb and U. The cause of the relative 235U excess in one sample does not appear to be from terrestrial contamination or the decay of short-lived 247Cm, but is more likely from fractionation of U isotopes during metal-silicate separation during core formation, exacerbated by the extreme U depletion in the planetary core. Due to limited Pb isotopic variation and terrestrial disturbance, no samples of this study produced useful age information; however the clear divergence from the previously assumed 238U/235U of any troilite in Muonionalusta introduces substantial uncertainty to the previously reported absolute age of the sample without knowledge of the 238U/235U of the sample. Uncertainties associated with U isotope heterogeneity do not allow for definition of a robust age of solidification and cooling for the IVA core. However, one sample of this work-paired with previous work using short

  15. Simultaneous estimation of lithospheric uplift rates and absolute sea level change in southwest Scandinavia from inversion of sea level data

    DEFF Research Database (Denmark)

    Nielsen, Lars; Hansen, Jens Morten; Hede, Mikkel Ulfeldt

    2014-01-01

    the relative sea level data. Similar independent data do not exist for ancient times. The purpose of this study is to test two simple inversion approaches for simultaneous estimation of lithospheric uplift rates and absolute sea level change rates for ancient times in areas where a dense coverage of relative...... sea level data exists and well-constrained average lithospheric movement values are known from, for example glacial isostatic adjustment (GIA) models. The inversion approaches are tested and used for simultaneous estimation of lithospheric uplift rates and absolute sea level change rates in southwest...... Scandinavia from modern relative sea level data series that cover the period from 1900 to 2000. In both approaches, a priori information is required to solve the inverse problem. A priori information about the average vertical lithospheric movement in the area of interest is critical for the quality...

  16. Absolute estimation of initial concentrations of amplicon in a real-time RT-PCR process

    Directory of Open Access Journals (Sweden)

    Kohn Michael

    2007-10-01

    Full Text Available Abstract Background Since real time PCR was first developed, several approaches to estimating the initial quantity of template in an RT-PCR reaction have been tried. While initially only the early thermal cycles corresponding to exponential duplication were used, lately there has been an effort to use all of the cycles in a PCR. The efforts have included both fitting empirical sigmoid curves and more elaborate mechanistic models that explore the chemical reactions taking place during each cycle. The more elaborate mechanistic models require many more parameters than can be fit from a single amplification, while the empirical models provide little insight and are difficult to tailor to specific reactants. Results We directly estimate the initial amount of amplicon using a simplified mechanistic model based on chemical reactions in the annealing step of the PCR. The basic model includes the duplication of DNA with the digestion of Taqman probe and the re-annealing between previously synthesized DNA strands of opposite orientation. By modelling the amount of Taqman probe digested and matching that with the observed fluorescence, the conversion factor between the number of fluorescing dye molecules and observed fluorescent emission can be estimated, along with the absolute initial amount of amplicon and the rate parameter for re-annealing. The model is applied to several PCR reactions with known amounts of amplicon and is shown to work reasonably well. An expanded version of the model allows duplication of amplicon without release of fluorescent dye, by adding 1 more parameter to the model. The additional process is helpful in most cases where the initial primer concentration exceeds the initial probe concentration. Software for applying the algorithm to data may be downloaded at http://www.niehs.nih.gov/research/resources/software/pcranalyzer/ Conclusion We present proof of the principle that a mechanistically based model can be fit to observations

  17. Dependence of absolute magnitudes (energies) of flares on the cluster age containing flare stars

    International Nuclear Information System (INIS)

    Parsamyan, Eh.S.

    1976-01-01

    Dependences between Δmsub(u) and msub(u) are given for the Orion, NGC 7000, Pleiades and Praesepe aggregations. Maximum absolute values of flares have been calculated for stars with different luminosities. It has been shown that the values of flares can be limited by a straight line which gives the representation on the distribution of maximum values of amplitudes for the stars with different luminosities in an aggregation. Presented are k and m 0 parameters characterizing the lines fot the Orion, NGC 7000, Pleiades and Praesepe aggregation and their age T dependence. From the dependence between k (angular coefficient of straight lines) and lgT for the aggregation with known T the age of those aggregation involving a great amount of flaring stars can be found. The age of flaring stars in the neighbourhood of the Sun has been determined. The age of UV Ceti has been shown by an order to exceed that of the rest stars

  18. Binomial Distribution Sample Confidence Intervals Estimation 7. Absolute Risk Reduction and ARR-like Expressions

    Directory of Open Access Journals (Sweden)

    Andrei ACHIMAŞ CADARIU

    2004-08-01

    Full Text Available Assessments of a controlled clinical trial suppose to interpret some key parameters as the controlled event rate, experimental event date, relative risk, absolute risk reduction, relative risk reduction, number needed to treat when the effect of the treatment are dichotomous variables. Defined as the difference in the event rate between treatment and control groups, the absolute risk reduction is the parameter that allowed computing the number needed to treat. The absolute risk reduction is compute when the experimental treatment reduces the risk for an undesirable outcome/event. In medical literature when the absolute risk reduction is report with its confidence intervals, the method used is the asymptotic one, even if it is well know that may be inadequate. The aim of this paper is to introduce and assess nine methods of computing confidence intervals for absolute risk reduction and absolute risk reduction – like function.Computer implementations of the methods use the PHP language. Methods comparison uses the experimental errors, the standard deviations, and the deviation relative to the imposed significance level for specified sample sizes. Six methods of computing confidence intervals for absolute risk reduction and absolute risk reduction-like functions were assessed using random binomial variables and random sample sizes.The experiments shows that the ADAC, and ADAC1 methods obtains the best overall performance of computing confidence intervals for absolute risk reduction.

  19. Age estimation by pulp/tooth ratio in lower premolars by orthopantomography.

    Science.gov (United States)

    Cameriere, Roberto; De Luca, Stefano; Alemán, Inmaculada; Ferrante, Luigi; Cingolani, Mariano

    2012-01-10

    Accurate age estimation has always been a problem for forensic scientists, and apposition of secondary dentine is often used as an indicator of age. Since 2004, in order to examine patterns of secondary dentine apposition, Cameriere et al. have been extensively studying the pulp/tooth area ratio of the canines by panoramic and peri-apical X-ray images. The main aim of this paper is to examine the relationship between age and age-related changes in the pulp/tooth area ratio in monoradicular teeth, with the exception of canines, by orthopantomography. A total of 606 orthopantomograms of Spanish white Caucasian patients (289 women and 317 men), aged between 18 and 75 years and coming from Bilbao and Granada (Spain), was analysed. Regression analysis of age of monoradicular teeth indicated that the lower premolars were the most closely correlated with age. An ANCOVA did not show significant differences between men and women. Multiple regression analysis, with age as dependent variable and pulp/tooth area ratio as predictor, yielded several formulae. R(2) ranged from 0.69 to 0.75 for a single lower premolar tooth and from 0.79 to 0.86 for multiple lower premolar teeth. Depending on the available number of premolar teeth, the mean of the absolute values of residual standard error, at 95% confidence interval, ranged between 4.34 and 6.02 years, showing that the pulp/tooth area ratio is a useful variable for assessing age with reasonable accuracy. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  20. Absolute Gravity Datum in the Age of Cold Atom Gravimeters

    Science.gov (United States)

    Childers, V. A.; Eckl, M. C.

    2014-12-01

    The international gravity datum is defined today by the International Gravity Standardization Net of 1971 (IGSN-71). The data supporting this network was measured in the 1950s and 60s using pendulum and spring-based gravimeter ties (plus some new ballistic absolute meters) to replace the prior protocol of referencing all gravity values to the earlier Potsdam value. Since this time, gravimeter technology has advanced significantly with the development and refinement of the FG-5 (the current standard of the industry) and again with the soon-to-be-available cold atom interferometric absolute gravimeters. This latest development is anticipated to provide improvement in the range of two orders of magnitude as compared to the measurement accuracy of technology utilized to develop ISGN-71. In this presentation, we will explore how the IGSN-71 might best be "modernized" given today's requirements and available instruments and resources. The National Geodetic Survey (NGS), along with other relevant US Government agencies, is concerned about establishing gravity control to establish and maintain high order geodetic networks as part of the nation's essential infrastructure. The need to modernize the nation's geodetic infrastructure was highlighted in "Precise Geodetic Infrastructure, National Requirements for a Shared Resource" National Academy of Science, 2010. The NGS mission, as dictated by Congress, is to establish and maintain the National Spatial Reference System, which includes gravity measurements. Absolute gravimeters measure the total gravity field directly and do not involve ties to other measurements. Periodic "intercomparisons" of multiple absolute gravimeters at reference gravity sites are used to constrain the behavior of the instruments to ensure that each would yield reasonably similar measurements of the same location (i.e. yield a sufficiently consistent datum when measured in disparate locales). New atomic interferometric gravimeters promise a significant

  1. The Age of Globular Clusters in Light of Hipparcos: Resolving the Age Problem?

    Science.gov (United States)

    Chaboyer, Brian; Demarque, P.; Kernan, Peter J.; Krauss, Lawrence M.

    1998-02-01

    We review five independent techniques that are used to set the distance scale to globular clusters, including subdwarf main-sequence fitting utilizing the recent Hipparcos parallax catalog. These data together all indicate that globular clusters are farther away than previously believed, implying a reduction in age estimates. We now adopt a best-fit value Mv (RR Lyrae stars) = 0.39 +/- 0.08 (statistical) at [Fe/H] = -1.9 with an additional uniform systematic uncertainty of +0.13-0.18. This new distance scale estimate is combined with a detailed numerical Monte Carlo study (previously reported by Chaboyer et al.) designed to assess the uncertainty associated with the theoretical age-turnoff luminosity relationship in order to estimate both the absolute age and uncertainty in age of the oldest globular clusters. Our best estimate for the mean age of the oldest globular clusters is now 11.5 +/- 1.3 Gyr, with a one-sided 95% confidence level lower limit of 9.5 Gyr. This represents a systematic shift of over 2 σ compared to our earlier estimate, owing completely to the new distance scale--a shift which we emphasize results not only from the Hipparcos data. This now provides a lower limit on the age of the universe that is consistent with either an open universe or with a flat matter-dominated universe (the latter requiring H0 explicitly quantifies how remaining uncertainties in the distance scale and stellar evolution models translate into uncertainties in the derived globular cluster ages. Simple formulae are provided that can be used to update our age estimate as improved determinations for various quantities become available. Formulae are also provided that can be used to derive the age and its uncertainty for a globular cluster, given the absolute magnitude of the turnoff or the point on the subgiant branch 0.05 mag redder than the turnoff.

  2. The juvenile face as a suitable age indicator in child pornography cases: a pilot study on the reliability of automated and visual estimation approaches.

    Science.gov (United States)

    Ratnayake, M; Obertová, Z; Dose, M; Gabriel, P; Bröker, H M; Brauckmann, M; Barkus, A; Rizgeliene, R; Tutkuviene, J; Ritz-Timme, S; Marasciuolo, L; Gibelli, D; Cattaneo, C

    2014-09-01

    In cases of suspected child pornography, the age of the victim represents a crucial factor for legal prosecution. The conventional methods for age estimation provide unreliable age estimates, particularly if teenage victims are concerned. In this pilot study, the potential of age estimation for screening purposes is explored for juvenile faces. In addition to a visual approach, an automated procedure is introduced, which has the ability to rapidly scan through large numbers of suspicious image data in order to trace juvenile faces. Age estimations were performed by experts, non-experts and the Demonstrator of a developed software on frontal facial images of 50 females aged 10-19 years from Germany, Italy, and Lithuania. To test the accuracy, the mean absolute error (MAE) between the estimates and the real ages was calculated for each examiner and the Demonstrator. The Demonstrator achieved the lowest MAE (1.47 years) for the 50 test images. Decreased image quality had no significant impact on the performance and classification results. The experts delivered slightly less accurate MAE (1.63 years). Throughout the tested age range, both the manual and the automated approach led to reliable age estimates within the limits of natural biological variability. The visual analysis of the face produces reasonably accurate age estimates up to the age of 18 years, which is the legally relevant age threshold for victims in cases of pedo-pornography. This approach can be applied in conjunction with the conventional methods for a preliminary age estimation of juveniles depicted on images.

  3. Calibration with Absolute Shrinkage

    DEFF Research Database (Denmark)

    Øjelund, Henrik; Madsen, Henrik; Thyregod, Poul

    2001-01-01

    In this paper, penalized regression using the L-1 norm on the estimated parameters is proposed for chemometric je calibration. The algorithm is of the lasso type, introduced by Tibshirani in 1996 as a linear regression method with bound on the absolute length of the parameters, but a modification...

  4. The absolute environmental performance of buildings

    DEFF Research Database (Denmark)

    Brejnrod, Kathrine Nykjær; Kalbar, Pradip; Petersen, Steffen

    2017-01-01

    Our paper presents a novel approach for absolute sustainability assessment of a building's environmental performance. It is demonstrated how the absolute sustainable share of the earth carrying capacity of a specific building type can be estimated using carrying capacity based normalization factors....... A building is considered absolute sustainable if its annual environmental burden is less than its share of the earth environmental carrying capacity. Two case buildings – a standard house and an upcycled single-family house located in Denmark – were assessed according to this approach and both were found...... to exceed the target values of three (almost four) of the eleven impact categories included in the study. The worst-case excess was for the case building, representing prevalent Danish building practices, which utilized 1563% of the Climate Change carrying capacity. Four paths to reach absolute...

  5. Model linear absolute and relative risk estimates for cancer induced by ionizing radiation in Mexican cohort of occupationally exposed

    International Nuclear Information System (INIS)

    Alvarez, R.J.T.; Trovar, M.V.M; González, J.F.

    2015-01-01

    From the rate of natural mortality m s cancer (t) for every 100 thousand habitants, modeled by a fourth-degree polynomial function of the age data of the Mexican population (2008), and assuming: a) a relationship 1: 5 of cancer induced radiation respect to presented spontaneously, b) a size of initial cohort No = 100 k SOPs, c) a speed of H E = (2 ± 1) mSv / received by the SOPs from 18 to 65 years, d) a latency of 8 years for cancer induction after irradiation, e) a time tracking cohort to 75 years, f) and taking the coefficients absolute and relative risk BEIRs induction of cancer models II and VII (excluding leukemia); It determined: BEIR II for a total of 125 and 400 deaths from cancer for absolute and relative linear models respectively. For BEIR VII has a number of fatal cases of 345 and 927 deaths respectively for absolute and relative linear model cancer. [es

  6. A Concurrent Mixed Methods Approach to Examining the Quantitative and Qualitative Meaningfulness of Absolute Magnitude Estimation Scales in Survey Research

    Science.gov (United States)

    Koskey, Kristin L. K.; Stewart, Victoria C.

    2014-01-01

    This small "n" observational study used a concurrent mixed methods approach to address a void in the literature with regard to the qualitative meaningfulness of the data yielded by absolute magnitude estimation scaling (MES) used to rate subjective stimuli. We investigated whether respondents' scales progressed from less to more and…

  7. Development of cancer risk estimates from epidemiologic studies

    International Nuclear Information System (INIS)

    Webster, E.W.

    1983-01-01

    Radiation risk estimates may be made for an increase in mortality from, or for an increase in incidence of, particular types of disease. For both endpoints, two numerical systems of risk expression are used: the absolute risk system (usually the excess deaths or cases per million persons per year per rad), and the relative risk system (usually excess deaths or cases per year per rad expressed as a percentage of those normally expected). Risks may be calculated for specific age groups or for a general population. An alternative in both risk systems is the estimation of cumulative of lifetime risk rather than annual risk (e.g. in excess deaths per million per rad over a specified long period including the remainder of lifespan). The derivation of both absolute and relative risks is illustrated by examples. The effects on risk estimates of latent period, follow-up time, age at exposure and age standardization within dose groups are illustrated. The dependence of the projected cumulative (lifetime) risk on the adoption of a constant absolute risk or constant relative risk is noted. The use of life-table data in the adjustment of cumulative risk for normal mortality following single or annual doses is briefly discussed

  8. Is an absolute level of cortical beta suppression required for proper movement? Magnetoencephalographic evidence from healthy aging.

    Science.gov (United States)

    Heinrichs-Graham, Elizabeth; Wilson, Tony W

    2016-07-01

    Previous research has connected a specific pattern of beta oscillatory activity to proper motor execution, but no study to date has directly examined how resting beta levels affect motor-related beta oscillatory activity in the motor cortex. Understanding this relationship is imperative to determining the basic mechanisms of motor control, as well as the impact of pathological beta oscillations on movement execution. In the current study, we used magnetoencephalography (MEG) and a complex movement paradigm to quantify resting beta activity and movement-related beta oscillations in the context of healthy aging. We chose healthy aging as a model because preliminary evidence suggests that beta activity is elevated in older adults, and thus by examining older and younger adults we were able to naturally vary resting beta levels. To this end, healthy younger and older participants were recorded during motor performance and at rest. Using beamforming, we imaged the peri-movement beta event-related desynchronization (ERD) and extracted virtual sensors from the peak voxels, which enabled absolute and relative beta power to be assessed. Interestingly, absolute beta power during the pre-movement baseline was much stronger in older relative to younger adults, and older adults also exhibited proportionally large beta desynchronization (ERD) responses during motor planning and execution compared to younger adults. Crucially, we found a significant relationship between spontaneous (resting) beta power and beta ERD magnitude in both primary motor cortices, above and beyond the effects of age. A similar link was found between beta ERD magnitude and movement duration. These findings suggest a direct linkage between beta reduction during movement and spontaneous activity in the motor cortex, such that as spontaneous beta power increases, a greater reduction in beta activity is required to execute movement. We propose that, on an individual level, the primary motor cortices have an

  9. Facial Asymmetry-Based Age Group Estimation: Role in Recognizing Age-Separated Face Images.

    Science.gov (United States)

    Sajid, Muhammad; Taj, Imtiaz Ahmad; Bajwa, Usama Ijaz; Ratyal, Naeem Iqbal

    2018-04-23

    Face recognition aims to establish the identity of a person based on facial characteristics. On the other hand, age group estimation is the automatic calculation of an individual's age range based on facial features. Recognizing age-separated face images is still a challenging research problem due to complex aging processes involving different types of facial tissues, skin, fat, muscles, and bones. Certain holistic and local facial features are used to recognize age-separated face images. However, most of the existing methods recognize face images without incorporating the knowledge learned from age group estimation. In this paper, we propose an age-assisted face recognition approach to handle aging variations. Inspired by the observation that facial asymmetry is an age-dependent intrinsic facial feature, we first use asymmetric facial dimensions to estimate the age group of a given face image. Deeply learned asymmetric facial features are then extracted for face recognition using a deep convolutional neural network (dCNN). Finally, we integrate the knowledge learned from the age group estimation into the face recognition algorithm using the same dCNN. This integration results in a significant improvement in the overall performance compared to using the face recognition algorithm alone. The experimental results on two large facial aging datasets, the MORPH and FERET sets, show that the proposed age group estimation based on the face recognition approach yields superior performance compared to some existing state-of-the-art methods. © 2018 American Academy of Forensic Sciences.

  10. Comparative analysis of old-age mortality estimations in Africa.

    Directory of Open Access Journals (Sweden)

    Eran Bendavid

    Full Text Available Survival to old ages is increasing in many African countries. While demographic tools for estimating mortality up to age 60 have improved greatly, mortality patterns above age 60 rely on models based on little or no demographic data. These estimates are important for social planning and demographic projections. We provide direct estimations of older-age mortality using survey data.Since 2005, nationally representative household surveys in ten sub-Saharan countries record counts of living and recently deceased household members: Burkina Faso, Côte d'Ivoire, Ethiopia, Namibia, Nigeria, Swaziland, Tanzania, Uganda, Zambia, and Zimbabwe. After accounting for age heaping using multiple imputation, we use this information to estimate probability of death in 5-year intervals ((5q(x. We then compare our (5q(x estimates to those provided by the World Health Organization (WHO and the United Nations Population Division (UNPD to estimate the differences in mortality estimates, especially among individuals older than 60 years old.We obtained information on 505,827 individuals (18.4% over age 60, 1.64% deceased. WHO and UNPD mortality models match our estimates closely up to age 60 (mean difference in probability of death -1.1%. However, mortality probabilities above age 60 are lower using our estimations than either WHO or UNPD. The mean difference between our sample and the WHO is 5.9% (95% CI 3.8-7.9% and between our sample is UNPD is 13.5% (95% CI 11.6-15.5%. Regardless of the comparator, the difference in mortality estimations rises monotonically above age 60.Mortality estimations above age 60 in ten African countries exhibit large variations depending on the method of estimation. The observed patterns suggest the possibility that survival in some African countries among adults older than age 60 is better than previously thought. Improving the quality and coverage of vital information in developing countries will become increasingly important with

  11. Age estimation in forensic sciences: application of combined aspartic acid racemization and radiocarbon analysis.

    Science.gov (United States)

    Alkass, Kanar; Buchholz, Bruce A; Ohtani, Susumu; Yamamoto, Toshiharu; Druid, Henrik; Spalding, Kirsty L

    2010-05-01

    Age determination of unknown human bodies is important in the setting of a crime investigation or a mass disaster because the age at death, birth date, and year of death as well as gender can guide investigators to the correct identity among a large number of possible matches. Traditional morphological methods used by anthropologists to determine age are often imprecise, whereas chemical analysis of tooth dentin, such as aspartic acid racemization, has shown reproducible and more precise results. In this study, we analyzed teeth from Swedish individuals using both aspartic acid racemization and radiocarbon methodologies. The rationale behind using radiocarbon analysis is that aboveground testing of nuclear weapons during the cold war (1955-1963) caused an extreme increase in global levels of carbon-14 ((14)C), which has been carefully recorded over time. Forty-four teeth from 41 individuals were analyzed using aspartic acid racemization analysis of tooth crown dentin or radiocarbon analysis of enamel, and 10 of these were split and subjected to both radiocarbon and racemization analysis. Combined analysis showed that the two methods correlated well (R(2) = 0.66, p Aspartic acid racemization also showed a good precision with an overall absolute error of 5.4 +/- 4.2 years. Whereas radiocarbon analysis gives an estimated year of birth, racemization analysis indicates the chronological age of the individual at the time of death. We show how these methods in combination can also assist in the estimation of date of death of an unidentified victim. This strategy can be of significant assistance in forensic casework involving dead victim identification.

  12. An automated technique to stage lower third molar development on panoramic radiographs for age estimation: a pilot study.

    Science.gov (United States)

    De Tobel, J; Radesh, P; Vandermeulen, D; Thevissen, P W

    2017-12-01

    Automated methods to evaluate growth of hand and wrist bones on radiographs and magnetic resonance imaging have been developed. They can be applied to estimate age in children and subadults. Automated methods require the software to (1) recognise the region of interest in the image(s), (2) evaluate the degree of development and (3) correlate this to the age of the subject based on a reference population. For age estimation based on third molars an automated method for step (1) has been presented for 3D magnetic resonance imaging and is currently being optimised (Unterpirker et al. 2015). To develop an automated method for step (2) based on lower third molars on panoramic radiographs. A modified Demirjian staging technique including ten developmental stages was developed. Twenty panoramic radiographs per stage per gender were retrospectively selected for FDI element 38. Two observers decided in consensus about the stages. When necessary, a third observer acted as a referee to establish the reference stage for the considered third molar. This set of radiographs was used as training data for machine learning algorithms for automated staging. First, image contrast settings were optimised to evaluate the third molar of interest and a rectangular bounding box was placed around it in a standardised way using Adobe Photoshop CC 2017 software. This bounding box indicated the region of interest for the next step. Second, several machine learning algorithms available in MATLAB R2017a software were applied for automated stage recognition. Third, the classification performance was evaluated in a 5-fold cross-validation scenario, using different validation metrics (accuracy, Rank-N recognition rate, mean absolute difference, linear kappa coefficient). Transfer Learning as a type of Deep Learning Convolutional Neural Network approach outperformed all other tested approaches. Mean accuracy equalled 0.51, mean absolute difference was 0.6 stages and mean linearly weighted kappa was

  13. Study of errors in absolute flux density measurements of Cassiopeia A

    International Nuclear Information System (INIS)

    Kanda, M.

    1975-10-01

    An error analysis for absolute flux density measurements of Cassiopeia A is discussed. The lower-bound quadrature-accumulation error for state-of-the-art measurements of the absolute flux density of Cas A around 7 GHz is estimated to be 1.71% for 3 sigma limits. The corresponding practicable error for the careful but not state-of-the-art measurement is estimated to be 4.46% for 3 sigma limits

  14. Graphs to estimate an individualized risk of breast cancer.

    Science.gov (United States)

    Benichou, J; Gail, M H; Mulvihill, J J

    1996-01-01

    Clinicians who counsel women about their risk for developing breast cancer need a rapid method to estimate individualized risk (absolute risk), as well as the confidence limits around that point. The Breast Cancer Detection Demonstration Project (BCDDP) model (sometimes called the Gail model) assumes no genetic model and simultaneously incorporates five risk factors, but involves cumbersome calculations and interpolations. This report provides graphs to estimate the absolute risk of breast cancer from the BCDDP model. The BCDDP recruited 280,000 women from 1973 to 1980 who were monitored for 5 years. From this cohort, 2,852 white women developed breast cancer and 3,146 controls were selected, all with complete risk-factor information. The BCDDP model, previously developed from these data, was used to prepare graphs that relate a specific summary relative-risk estimate to the absolute risk of developing breast cancer over intervals of 10, 20, and 30 years. Once a summary relative risk is calculated, the appropriate graph is chosen that shows the 10-, 20-, or 30-year absolute risk of developing breast cancer. A separate graph gives the 95% confidence limits around the point estimate of absolute risk. Once a clinician rules out a single gene trait that predisposes to breast cancer and elicits information on age and four risk factors, the tables and figures permit an estimation of a women's absolute risk of developing breast cancer in the next three decades. These results are intended to be applied to women who undergo regular screening. They should be used only in a formal counseling program to maximize a woman's understanding of the estimates and the proper use of them.

  15. Discriminating Projections for Estimating Face Age in Wild Images

    Energy Technology Data Exchange (ETDEWEB)

    Tokola, Ryan A [ORNL; Bolme, David S [ORNL; Ricanek, Karl [ORNL; Barstow, Del R [ORNL; Boehnen, Chris Bensing [ORNL

    2014-01-01

    We introduce a novel approach to estimating the age of a human from a single uncontrolled image. Current face age estimation algorithms work well in highly controlled images, and some are robust to changes in illumination, but it is usually assumed that images are close to frontal. This bias is clearly seen in the datasets that are commonly used to evaluate age estimation, which either entirely or mostly consist of frontal images. Using pose-specific projections, our algorithm maps image features into a pose-insensitive latent space that is discriminative with respect to age. Age estimation is then performed using a multi-class SVM. We show that our approach outperforms other published results on the Images of Groups dataset, which is the only age-related dataset with a non-trivial number of off-axis face images, and that we are competitive with recent age estimation algorithms on the mostly-frontal FG-NET dataset. We also experimentally demonstrate that our feature projections introduce insensitivity to pose.

  16. Estimation of Cumulative Absolute Velocity using Empirical Green's Function Method

    International Nuclear Information System (INIS)

    Park, Dong Hee; Yun, Kwan Hee; Chang, Chun Joong; Park, Se Moon

    2009-01-01

    In recognition of the needs to develop a new criterion for determining when the OBE (Operating Basis Earthquake) has been exceeded at nuclear power plants, Cumulative Absolute Velocity (CAV) was introduced by EPRI. The concept of CAV is the area accumulation with the values more than 0.025g occurred during every one second. The equation of the CAV is as follows. CAV = ∫ 0 max |a(t)|dt (1) t max = duration of record, a(t) = acceleration (>0.025g) Currently, the OBE exceedance criteria in Korea is Peak Ground Acceleration (PGA, PGA>0.1g). When Odesan earthquake (M L =4.8, January 20th, 2007) and Gyeongju earthquake (M L =3.4, June 2nd, 1999) were occurred, we have had already experiences of PGA greater than 0.1g that did not even cause any damage to the poorly-designed structures nearby. This moderate earthquake has motivated Korea to begin the use of the CAV for OBE exceedance criteria for NPPs. Because the present OBE level has proved itself to be a poor indicator for small-to-moderate earthquakes, for which the low OBE level can cause an inappropriate shut down the plant. A more serious possibility is that this scenario will become a reality at a very high level. Empirical Green's Function method was a simulation technique which can estimate the CAV value and it is hereby introduced

  17. A holistic approach to age estimation in refugee children.

    Science.gov (United States)

    Sypek, Scott A; Benson, Jill; Spanner, Kate A; Williams, Jan L

    2016-06-01

    Many refugee children arriving in Australia have an inaccurately documented date of birth (DOB). A medical assessment of a child's age is often requested when there is a concern that their documented DOB is incorrect. This study's aim was to assess the accuracy a holistic age assessment tool (AAT) in estimating the age of refugee children newly settled in Australia. A holistic AAT that combines medical and non-medical approaches was used to estimate the ages of 60 refugee children with a known DOB. The tool used four components to assess age: an oral narrative, developmental assessment, anthropometric measures and pubertal assessment. Assessors were blinded to the true age of the child. Correlation coefficients for the actual and estimated age were calculated for the tool overall and individual components. The correlation coefficient between the actual and estimated age from the AAT was very strong at 0.9802 (boys 0.9748, girls 0.9876). The oral narrative component of the tool performed best (R = 0.9603). Overall, 86.7% of age estimates were within 1 year of the true age. The range of differences was -1.43 to 3.92 years with a standard deviation of 0.77 years (9.24 months). The AAT is a holistic, simple and safe instrument that can be used to estimate age in refugee children with results comparable with radiological methods currently used. © 2016 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).

  18. A statistical method for estimating rates of soil development and ages of geologic deposits: A design for soil-chronosequence studies

    Science.gov (United States)

    Switzer, P.; Harden, J.W.; Mark, R.K.

    1988-01-01

    A statistical method for estimating rates of soil development in a given region based on calibration from a series of dated soils is used to estimate ages of soils in the same region that are not dated directly. The method is designed specifically to account for sampling procedures and uncertainties that are inherent in soil studies. Soil variation and measurement error, uncertainties in calibration dates and their relation to the age of the soil, and the limited number of dated soils are all considered. Maximum likelihood (ML) is employed to estimate a parametric linear calibration curve, relating soil development to time or age on suitably transformed scales. Soil variation on a geomorphic surface of a certain age is characterized by replicate sampling of soils on each surface; such variation is assumed to have a Gaussian distribution. The age of a geomorphic surface is described by older and younger bounds. This technique allows age uncertainty to be characterized by either a Gaussian distribution or by a triangular distribution using minimum, best-estimate, and maximum ages. The calibration curve is taken to be linear after suitable (in certain cases logarithmic) transformations, if required, of the soil parameter and age variables. Soil variability, measurement error, and departures from linearity are described in a combined fashion using Gaussian distributions with variances particular to each sampled geomorphic surface and the number of sample replicates. Uncertainty in age of a geomorphic surface used for calibration is described using three parameters by one of two methods. In the first method, upper and lower ages are specified together with a coverage probability; this specification is converted to a Gaussian distribution with the appropriate mean and variance. In the second method, "absolute" older and younger ages are specified together with a most probable age; this specification is converted to an asymmetric triangular distribution with mode at the

  19. Calibrating recruitment estimates for mourning doves from harvest age ratios

    Science.gov (United States)

    Miller, David A.; Otis, David L.

    2010-01-01

    We examined results from the first national-scale effort to estimate mourning dove (Zenaida macroura) age ratios and developed a simple, efficient, and generalizable methodology for calibrating estimates. Our method predicted age classes of unknown-age wings based on backward projection of molt distributions from fall harvest collections to preseason banding. We estimated 1) the proportion of late-molt individuals in each age class, and 2) the molt rates of juvenile and adult birds. Monte Carlo simulations demonstrated our estimator was minimally biased. We estimated model parameters using 96,811 wings collected from hunters and 42,189 birds banded during preseason from 68 collection blocks in 22 states during the 2005–2007 hunting seasons. We also used estimates to derive a correction factor, based on latitude and longitude of samples, which can be applied to future surveys. We estimated differential vulnerability of age classes to harvest using data from banded birds and applied that to harvest age ratios to estimate population age ratios. Average, uncorrected age ratio of known-age wings for states that allow hunting was 2.25 (SD 0.85) juveniles:adult, and average, corrected ratio was 1.91 (SD 0.68), as determined from harvest age ratios from an independent sample of 41,084 wings collected from random hunters in 2007 and 2008. We used an independent estimate of differential vulnerability to adjust corrected harvest age ratios and estimated the average population age ratio as 1.45 (SD 0.52), a direct measure of recruitment rates. Average annual recruitment rates were highest east of the Mississippi River and in the northwestern United States, with lower rates between. Our results demonstrate a robust methodology for calibrating recruitment estimates for mourning doves and represent the first large-scale estimates of recruitment for the species. Our methods can be used by managers to correct future harvest survey data to generate recruitment estimates for use in

  20. MEAN OF MEDIAN ABSOLUTE DERIVATION TECHNIQUE MEAN ...

    African Journals Online (AJOL)

    eobe

    development of mean of median absolute derivation technique based on the based on the based on .... of noise mean to estimate the speckle noise variance. Noise mean property ..... Foraging Optimization,” International Journal of. Advanced ...

  1. Absolute pitch: a case study.

    Science.gov (United States)

    Vernon, P E

    1977-11-01

    The auditory skill known as 'absolute pitch' is discussed, and it is shown that this differs greatly in accuracy of identification or reproduction of musical tones from ordinary discrimination of 'tonal height' which is to some extent trainable. The present writer possessed absolute pitch for almost any tone or chord over the normal musical range, from about the age of 17 to 52. He then started to hear all music one semitone too high, and now at the age of 71 it is heard a full tone above the true pitch. Tests were carried out under controlled conditions, in which 68 to 95 per cent of notes were identified as one semitone or one tone higher than they should be. Changes with ageing seem more likely to occur in the elasticity of the basilar membrane mechanisms than in the long-term memory which is used for aural analysis of complex sounds. Thus this experience supports the view that some resolution of complex sounds takes place at the peripheral sense organ, and this provides information which can be incorrect, for interpretation by the cortical centres.

  2. Dental maturity of Saudi children: Role of ethnicity in age determination

    International Nuclear Information System (INIS)

    Baghdadi, Ziad D.

    2013-01-01

    Demirjian's dental maturity scores and curves have been widely used for human age determination. Several authors have reported considerable differences between the true and estimated age based on the Demirjian curves, which have been accounted for by ethnicity. The purpose of the current study was to assess the role of ethnicity-specific dental maturation curves in age estimation of Saudi children. A sample of 452 healthy Saudi children aged 4 to 14 years were aged based on the original French-Canadian Demirjian curves and several modified Demirjian curves specified for certain ethnic groups: Saudi, Kuwaiti, Polish, Dutch, Pakistani, and Belgian. One-way ANOVA and a post hoc Scheffe's test were used to assess the differences between chronological age and dental age estimated by the different curves (P<0.05). The curves designed for Dutch, Polish, Saudi, and Belgian (5th percentile) populations had a significantly lower error in estimating age than the original French-Canadian and Belgian (50th percentile) curves. The optimal curve for males was the Saudi one, with a mean absolute difference between estimated age and chronological age of 8.6 months. For females, the optimal curve was the Polish one, with a mean absolute difference of 7.4 months. It was revealed that accurate age determination was not related to certain ethnicity-specific curves. We conclude that ethnicity might play a role in age determination, but not a principal one.

  3. Dental maturity of Saudi children: Role of ethnicity in age determination

    Energy Technology Data Exchange (ETDEWEB)

    Baghdadi, Ziad D. [Dept. of Preventive Dentistry, Riyadh Colleges of Dentistry and Pharmacy, Riyadh (Saudi Arabia)

    2013-12-15

    Demirjian's dental maturity scores and curves have been widely used for human age determination. Several authors have reported considerable differences between the true and estimated age based on the Demirjian curves, which have been accounted for by ethnicity. The purpose of the current study was to assess the role of ethnicity-specific dental maturation curves in age estimation of Saudi children. A sample of 452 healthy Saudi children aged 4 to 14 years were aged based on the original French-Canadian Demirjian curves and several modified Demirjian curves specified for certain ethnic groups: Saudi, Kuwaiti, Polish, Dutch, Pakistani, and Belgian. One-way ANOVA and a post hoc Scheffe's test were used to assess the differences between chronological age and dental age estimated by the different curves (P<0.05). The curves designed for Dutch, Polish, Saudi, and Belgian (5th percentile) populations had a significantly lower error in estimating age than the original French-Canadian and Belgian (50th percentile) curves. The optimal curve for males was the Saudi one, with a mean absolute difference between estimated age and chronological age of 8.6 months. For females, the optimal curve was the Polish one, with a mean absolute difference of 7.4 months. It was revealed that accurate age determination was not related to certain ethnicity-specific curves. We conclude that ethnicity might play a role in age determination, but not a principal one.

  4. Estimating Gestational Age From Ultrasound Fetal Biometrics.

    Science.gov (United States)

    Skupski, Daniel W; Owen, John; Kim, Sungduk; Fuchs, Karin M; Albert, Paul S; Grantz, Katherine L

    2017-08-01

    To compare the accuracy of a new formula with one developed in 1984 (and still in common use) and to develop and compare racial and ethnic-specific and racial and ethnic-neutral formulas. The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies-Singletons was a prospective cohort study that recruited women in four self-reported racial-ethnic groups-non-Hispanic black, Hispanic, non-Hispanic white, and Asian-with singleton gestations from 12 U.S. centers (2009-2013). Women with a certain last menstrual period confirmed by first-trimester ultrasonogram had longitudinal fetal measurements by credentialed study ultrasonographers blinded to the gestational age at their five follow-up visits. Regression analyses were performed with linear mixed models to develop gestational age estimating formulas. Repeated cross-validation was used for validation. The estimation error was defined as the mean squared difference between the estimated and observed gestational age and was used to compare the formulas' accuracy. The new formula estimated the gestational age (±2 SD) within ±7 days from 14 to 20 weeks of gestation, ±10 days from 21 to 27 weeks of gestation, and ±17 days from 28 to 40 weeks of gestation. The new formula performed significantly better than a formula developed in 1984 with an estimation error of 10.4 compared with 11.2 days from 21 to 27 weeks of gestation and 17.0 compared with 19.8 days at 28-40 weeks of gestation, respectively. Racial and ethnic-specific formulas did not outperform the racial and ethnic-neutral formula. The NICHD gestational age estimation formula is associated with smaller errors than a well-established historical formula. Racial and ethnic-specific formulas are not superior to a racial-ethnic-neutral one.

  5. Bayesian phylogenetic estimation of fossil ages.

    Science.gov (United States)

    Drummond, Alexei J; Stadler, Tanja

    2016-07-19

    Recent advances have allowed for both morphological fossil evidence and molecular sequences to be integrated into a single combined inference of divergence dates under the rule of Bayesian probability. In particular, the fossilized birth-death tree prior and the Lewis-Mk model of discrete morphological evolution allow for the estimation of both divergence times and phylogenetic relationships between fossil and extant taxa. We exploit this statistical framework to investigate the internal consistency of these models by producing phylogenetic estimates of the age of each fossil in turn, within two rich and well-characterized datasets of fossil and extant species (penguins and canids). We find that the estimation accuracy of fossil ages is generally high with credible intervals seldom excluding the true age and median relative error in the two datasets of 5.7% and 13.2%, respectively. The median relative standard error (RSD) was 9.2% and 7.2%, respectively, suggesting good precision, although with some outliers. In fact, in the two datasets we analyse, the phylogenetic estimate of fossil age is on average less than 2 Myr from the mid-point age of the geological strata from which it was excavated. The high level of internal consistency found in our analyses suggests that the Bayesian statistical model employed is an adequate fit for both the geological and morphological data, and provides evidence from real data that the framework used can accurately model the evolution of discrete morphological traits coded from fossil and extant taxa. We anticipate that this approach will have diverse applications beyond divergence time dating, including dating fossils that are temporally unconstrained, testing of the 'morphological clock', and for uncovering potential model misspecification and/or data errors when controversial phylogenetic hypotheses are obtained based on combined divergence dating analyses.This article is part of the themed issue 'Dating species divergences using

  6. Age estimation by amino acid racemization in human teeth.

    Science.gov (United States)

    Ohtani, Susumu; Yamamoto, Toshiharu

    2010-11-01

    When an unidentified body is found, it is essential to establish the personal identity of the body in addition to investigating the cause of death. Identification is one of the most important functions of forensic dentistry. Fingerprint, dental, and DNA analysis can be used to accurately identify a body. However, if no information is available for identification, age estimation can contribute to the resolution of a case. The authors have been using aspartic acid racemization rates in dentin (D-aspartic acid/L-aspartic acid: D/L Asp) as an index for age estimation and have obtained satisfactory results. We report five cases of age estimation using the racemization method. In all five cases, estimated ages were accurate within a range ±3 years. We conclude that the racemization method is a reliable and practical method for estimating age. © 2010 American Academy of Forensic Sciences.

  7. Dental age estimation: the role of probability estimates at the 10 year threshold.

    Science.gov (United States)

    Lucas, Victoria S; McDonald, Fraser; Neil, Monica; Roberts, Graham

    2014-08-01

    The use of probability at the 18 year threshold has simplified the reporting of dental age estimates for emerging adults. The availability of simple to use widely available software has enabled the development of the probability threshold for individual teeth in growing children. Tooth development stage data from a previous study at the 10 year threshold were reused to estimate the probability of developing teeth being above or below the 10 year thresh-hold using the NORMDIST Function in Microsoft Excel. The probabilities within an individual subject are averaged to give a single probability that a subject is above or below 10 years old. To test the validity of this approach dental panoramic radiographs of 50 female and 50 male children within 2 years of the chronological age were assessed with the chronological age masked. Once the whole validation set of 100 radiographs had been assessed the masking was removed and the chronological age and dental age compared. The dental age was compared with chronological age to determine whether the dental age correctly or incorrectly identified a validation subject as above or below the 10 year threshold. The probability estimates correctly identified children as above or below on 94% of occasions. Only 2% of the validation group with a chronological age of less than 10 years were assigned to the over 10 year group. This study indicates the very high accuracy of assignment at the 10 year threshold. Further work at other legally important age thresholds is needed to explore the value of this approach to the technique of age estimation. Copyright © 2014. Published by Elsevier Ltd.

  8. Western Saudi adolescent age estimation utilising third molar development.

    Science.gov (United States)

    Alshihri, Amin M; Kruger, Estie; Tennant, Marc

    2014-07-01

    The aim of this study was to establish reference data on third molar morphology/development for age estimation in Western Saudi adolescents, between ages 14 and 23 years of old. The orthopantomograms of 130 individuals (males and females), were examined, and the stage of third molar development were evaluated. Mean ages, standard deviations, and percentile distributions are presented for each stage of development. The mean estimated age for all participants (n = 130) was 219.7 months, and this differed significantly (P age (226.5 months). Deviations of predicted age from real age showed 28.5% of all participants had their age estimated within 1 year (±12 months) of their chronological age. Most (43%) had their age underestimated by more than 12 months and the remaining 28.5% had their age overestimated by more than 12 months of their chronological age. Differences in left-right symmetry information of third molars were detected and were higher in the maxilla (92%) than in the mandible (82%). For all molars reaching stage "H" most individuals (males and females) were over the age 18 years of old. Males reach the developmental stages earlier than females. Third molar tooth development can be reliably used to generate mean age and the estimated age range for an individual of unknown chronological age. Further studies with large populations are needed for better statistical results.

  9. Age synthesis and estimation via faces: a survey.

    Science.gov (United States)

    Fu, Yun; Guo, Guodong; Huang, Thomas S

    2010-11-01

    Human age, as an important personal trait, can be directly inferred by distinct patterns emerging from the facial appearance. Derived from rapid advances in computer graphics and machine vision, computer-based age synthesis and estimation via faces have become particularly prevalent topics recently because of their explosively emerging real-world applications, such as forensic art, electronic customer relationship management, security control and surveillance monitoring, biometrics, entertainment, and cosmetology. Age synthesis is defined to rerender a face image aesthetically with natural aging and rejuvenating effects on the individual face. Age estimation is defined to label a face image automatically with the exact age (year) or the age group (year range) of the individual face. Because of their particularity and complexity, both problems are attractive yet challenging to computer-based application system designers. Large efforts from both academia and industry have been devoted in the last a few decades. In this paper, we survey the complete state-of-the-art techniques in the face image-based age synthesis and estimation topics. Existing models, popular algorithms, system performances, technical difficulties, popular face aging databases, evaluation protocols, and promising future directions are also provided with systematic discussions.

  10. Evaluation and reliability of bone histological age estimation methods

    African Journals Online (AJOL)

    Human age estimation at death plays a vital role in forensic anthropology and bioarchaeology. Researchers used morphological and histological methods to estimate human age from their skeletal remains. This paper discussed different histological methods that used human long bones and ribs to determine age ...

  11. Global Kalman filter approaches to estimate absolute angles of lower limb segments.

    Science.gov (United States)

    Nogueira, Samuel L; Lambrecht, Stefan; Inoue, Roberto S; Bortole, Magdo; Montagnoli, Arlindo N; Moreno, Juan C; Rocon, Eduardo; Terra, Marco H; Siqueira, Adriano A G; Pons, Jose L

    2017-05-16

    In this paper we propose the use of global Kalman filters (KFs) to estimate absolute angles of lower limb segments. Standard approaches adopt KFs to improve the performance of inertial sensors based on individual link configurations. In consequence, for a multi-body system like a lower limb exoskeleton, the inertial measurements of one link (e.g., the shank) are not taken into account in other link angle estimations (e.g., foot). Global KF approaches, on the other hand, correlate the collective contribution of all signals from lower limb segments observed in the state-space model through the filtering process. We present a novel global KF (matricial global KF) relying only on inertial sensor data, and validate both this KF and a previously presented global KF (Markov Jump Linear Systems, MJLS-based KF), which fuses data from inertial sensors and encoders from an exoskeleton. We furthermore compare both methods to the commonly used local KF. The results indicate that the global KFs performed significantly better than the local KF, with an average root mean square error (RMSE) of respectively 0.942° for the MJLS-based KF, 1.167° for the matrical global KF, and 1.202° for the local KFs. Including the data from the exoskeleton encoders also resulted in a significant increase in performance. The results indicate that the current practice of using KFs based on local models is suboptimal. Both the presented KF based on inertial sensor data, as well our previously presented global approach fusing inertial sensor data with data from exoskeleton encoders, were superior to local KFs. We therefore recommend to use global KFs for gait analysis and exoskeleton control.

  12. Age estimation based on aspartic acid racemization in human sclera.

    Science.gov (United States)

    Klumb, Karolin; Matzenauer, Christian; Reckert, Alexandra; Lehmann, Klaus; Ritz-Timme, Stefanie

    2016-01-01

    Age estimation based on racemization of aspartic acid residues (AAR) in permanent proteins has been established in forensic medicine for years. While dentine is the tissue of choice for this molecular method of age estimation, teeth are not always available which leads to the need to identify other suitable tissues. We examined the suitability of total tissue samples of human sclera for the estimation of age at death. Sixty-five samples of scleral tissue were analyzed. The samples were hydrolyzed and after derivatization, the extent of aspartic acid racemization was determined by gas chromatography. The degree of AAR increased with age. In samples from younger individuals, the correlation of age and D-aspartic acid content was closer than in samples from older individuals. The age-dependent racemization in total tissue samples proves that permanent or at least long-living proteins are present in scleral tissue. The correlation of AAR in human sclera and age at death is close enough to serve as basis for age estimation. However, the precision of age estimation by this method is lower than that of age estimation based on the analysis of dentine which is due to molecular inhomogeneities of total tissue samples of sclera. Nevertheless, the approach may serve as a valuable alternative or addition in exceptional cases.

  13. Combining Facial Dynamics With Appearance for Age Estimation

    NARCIS (Netherlands)

    Dibeklioğlu, H.; Alnajar, F.; Salah, A.A.; Gevers, T.

    2015-01-01

    Estimating the age of a human from the captured images of his/her face is a challenging problem. In general, the existing approaches to this problem use appearance features only. In this paper, we show that in addition to appearance information, facial dynamics can be leveraged in age estimation. We

  14. Aspartic acid racemization in dentin of the third molar for age estimation of the Chaoshan population in South China.

    Science.gov (United States)

    Chen, Shisheng; Lv, Yanyi; Wang, Dian; Yu, Xiaojun

    2016-09-01

    Aspartic acid racemization in teeth has been increasingly used to estimate chronological age with a considerably high accuracy in forensic practice. The Chaoshan population in South China is relatively isolated in geography, and has specific lifestyle and dietary inhibits. It is still unknown whether this method is suitable for this population. The aim of this study was to analyze the relationship between chronological age and the d/l aspartic acid ratio in dentin in the third molar tooth of the Chaoshan population. Fifty-eight non-carious third molar teeth (31 mandibles and 27 maxillae), from 58 living individuals of known age (24 males and 34 females), were retrieved. Dentin was extracted from these teeth. The d- and l-aspartic acids in dentins were separated and detected by high performance liquid chromatography (HPLC). Linear regression was performed between the d/l aspartic acid ratio of dentins and chronological age. Results showed that the correlation coefficient (r) was 0.969, and the mean absolute error (MAE) was 2.19 years, its standard deviation (SD) was ±1.53 years, indicating excellent correlation. There was no significant difference in racemization rates of dentin between sexes (P=0.113, F=2.6), or between mandibles and maxillae (P=0.964, F=0.000). Results indicate that the ratio of the d and l forms of aspartic acid of dentins, in the third molar, is closely correlated with chronological age, special lifestyle do no obviously affect the accuracy of the age estimations by aspartic acid racemization of the dentin in the third molar and that aspartic acid racemization in the third molar dentin can be used as an accurate method to estimate chronological age in the Chaoshan population in South China. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  15. Methods for the quantitative comparison of molecular estimates of clade age and the fossil record.

    Science.gov (United States)

    Clarke, Julia A; Boyd, Clint A

    2015-01-01

    Approaches quantifying the relative congruence, or incongruence, of molecular divergence estimates and the fossil record have been limited. Previously proposed methods are largely node specific, assessing incongruence at particular nodes for which both fossil data and molecular divergence estimates are available. These existing metrics, and other methods that quantify incongruence across topologies including entirely extinct clades, have so far not taken into account uncertainty surrounding both the divergence estimates and the ages of fossils. They have also treated molecular divergence estimates younger than previously assessed fossil minimum estimates of clade age as if they were the same as cases in which they were older. However, these cases are not the same. Recovered divergence dates younger than compared oldest known occurrences require prior hypotheses regarding the phylogenetic position of the compared fossil record and standard assumptions about the relative timing of morphological and molecular change to be incorrect. Older molecular dates, by contrast, are consistent with an incomplete fossil record and do not require prior assessments of the fossil record to be unreliable in some way. Here, we compare previous approaches and introduce two new descriptive metrics. Both metrics explicitly incorporate information on uncertainty by utilizing the 95% confidence intervals on estimated divergence dates and data on stratigraphic uncertainty concerning the age of the compared fossils. Metric scores are maximized when these ranges are overlapping. MDI (minimum divergence incongruence) discriminates between situations where molecular estimates are younger or older than known fossils reporting both absolute fit values and a number score for incompatible nodes. DIG range (divergence implied gap range) allows quantification of the minimum increase in implied missing fossil record induced by enforcing a given set of molecular-based estimates. These metrics are used

  16. Efficacy of intrahepatic absolute alcohol in unrespectable hepatocellular carcinoma

    International Nuclear Information System (INIS)

    Farooqi, J.I.; Hameed, K.; Khan, I.U.; Shah, S.

    2001-01-01

    To determine efficacy of intrahepatic absolute alcohol injection in researchable hepatocellular carcinoma. A randomized, controlled, experimental and interventional clinical trial. Gastroenterology Department, PGMI, Hayatabad Medical Complex, Peshawar during the period from June, 1998 to June, 2000. Thirty patients were treated by percutaneous, intrahepatic absolute alcohol injection sin repeated sessions, 33 patients were not given or treated with alcohol to serve as control. Both the groups were comparable for age, sex and other baseline characteristics. Absolute alcohol therapy significantly improved quality of life of patients, reduced the tumor size and mortality as well as showed significantly better results regarding survival (P< 0.05) than the patients of control group. We conclude that absolute alcohol is a beneficial and safe palliative treatment measure in advanced hepatocellular carcinoma (HCC). (author)

  17. Absolute marine gravimetry with matter-wave interferometry.

    Science.gov (United States)

    Bidel, Y; Zahzam, N; Blanchard, C; Bonnin, A; Cadoret, M; Bresson, A; Rouxel, D; Lequentrec-Lalancette, M F

    2018-02-12

    Measuring gravity from an aircraft or a ship is essential in geodesy, geophysics, mineral and hydrocarbon exploration, and navigation. Today, only relative sensors are available for onboard gravimetry. This is a major drawback because of the calibration and drift estimation procedures which lead to important operational constraints. Atom interferometry is a promising technology to obtain onboard absolute gravimeter. But, despite high performances obtained in static condition, no precise measurements were reported in dynamic. Here, we present absolute gravity measurements from a ship with a sensor based on atom interferometry. Despite rough sea conditions, we obtained precision below 10 -5  m s -2 . The atom gravimeter was also compared with a commercial spring gravimeter and showed better performances. This demonstration opens the way to the next generation of inertial sensors (accelerometer, gyroscope) based on atom interferometry which should provide high-precision absolute measurements from a moving platform.

  18. Obtaining appropriate interval estimates for age when multiple indicators are used

    DEFF Research Database (Denmark)

    Fieuws, Steffen; Willems, Guy; Larsen, Sara Tangmose

    2016-01-01

    When an estimate of age is needed, typically multiple indicators are present as found in skeletal or dental information. There exists a vast literature on approaches to estimate age from such multivariate data. Application of Bayes' rule has been proposed to overcome drawbacks of classical regres...... the need for interval estimation. To illustrate and evaluate the method, Köhler et al. (1995) third molar scores are used to estimate the age in a dataset of 3200 male subjects in the juvenile age range.......When an estimate of age is needed, typically multiple indicators are present as found in skeletal or dental information. There exists a vast literature on approaches to estimate age from such multivariate data. Application of Bayes' rule has been proposed to overcome drawbacks of classical...... regression models but becomes less trivial as soon as the number of indicators increases. Each of the age indicators can lead to a different point estimate ("the most plausible value for age") and a prediction interval ("the range of possible values"). The major challenge in the combination of multiple...

  19. Regional and site-specific absolute humidity data for use in tritium dose calculations

    International Nuclear Information System (INIS)

    Etnier, E.L.

    1980-01-01

    Due to the potential variability in average absolute humidity over the continental U.S., and the dependence of atmospheric 3 H specific activity on absolute humidity, availability of regional absolute humidity data is of value in estimating the radiological significance of 3 H releases. Most climatological data are in the form of relative humidity, which must be converted to absolute humidity for dose calculations. Absolute humidity was calculated for 218 points across the U.S., using the 1977 annual summary of U.S. Climatological Data, and is given in a table. Mean regional values are shown on a map. (author)

  20. Age estimation in the living: Transition analysis on developing third molars.

    Science.gov (United States)

    Tangmose, Sara; Thevissen, Patrick; Lynnerup, Niels; Willems, Guy; Boldsen, Jesper

    2015-12-01

    A radiographic assessment of third molar development is essential for differentiating between juveniles and adolescents in forensic age estimations. As the developmental stages of third molars are highly correlated, age estimates based on a combination of a full set of third molar scores are statistically complicated. Transition analysis (TA) is a statistical method developed for estimating age at death in skeletons, which combines several correlated developmental traits into one age estimate including a 95% prediction interval. The aim of this study was to evaluate the performance of TA in the living on a full set of third molar scores. A cross sectional sample of 854 panoramic radiographs, homogenously distributed by sex and age (15.0-24.0 years), were randomly split in two; a reference sample for obtaining age estimates including a 95% prediction interval according to TA; and a validation sample to test the age estimates against actual age. The mean inaccuracy of the age estimates was 1.82 years (±1.35) in males and 1.81 years (±1.44) in females. The mean bias was 0.55 years (±2.20) in males and 0.31 years (±2.30) in females. Of the actual ages, 93.7% of the males and 95.9% of the females (validation sample) fell within the 95% prediction interval. Moreover, at a sensitivity and specificity of 0.824 and 0.937 in males and 0.814 and 0.827 in females, TA performs well in differentiating between being a minor as opposed to an adult. Although accuracy does not outperform other methods, TA provides unbiased age estimates which minimize the risk of wrongly estimating minors as adults. Furthermore, when corrected ad hoc, TA produces appropriate prediction intervals. As TA allows expansion with additional traits, i.e. stages of development of the left hand-wrist and the clavicle, it has a great potential for future more accurate and reproducible age estimates, including an estimated probability of having attained the legal age limit of 18 years. Copyright © 2015

  1. Improved Strategies and Optimization of Calibration Models for Real-time PCR Absolute Quantification

    Science.gov (United States)

    Real-time PCR absolute quantification applications rely on the use of standard curves to make estimates of DNA target concentrations in unknown samples. Traditional absolute quantification approaches dictate that a standard curve must accompany each experimental run. However, t...

  2. Absolute risk, absolute risk reduction and relative risk

    Directory of Open Access Journals (Sweden)

    Jose Andres Calvache

    2012-12-01

    Full Text Available This article illustrates the epidemiological concepts of absolute risk, absolute risk reduction and relative risk through a clinical example. In addition, it emphasizes the usefulness of these concepts in clinical practice, clinical research and health decision-making process.

  3. Northern Chinese dental ages estimated from southern Chinese reference datasets closely correlate with chronological age

    Directory of Open Access Journals (Sweden)

    Hai Ming Wong

    2016-12-01

    Full Text Available While northern and southern Chinese are genetically correlated, there exists notable environmental differences in their living conditions. This study aimed to evaluate validity of the southern Chinese reference dataset for dental age estimation applied to northern Chinese. Dental panoramic tomographs of 437 northern Chinese aged 3 to 21 years were analysed. All the left maxillary and mandibular permanent teeth plus the 2 third molars on the right side were scored based on Demirjian’s classification of tooth development stages. Mean and standard error of dental age were obtained for each tooth development stage, followed by random effect meta-analysis for mean dental age estimation. Validity of the method was examined through measures of agreement (95% limits of agreement, standard error of measurement, and Lin’s concordance correlation coefficient and measure of reliability (Intraclass correlation coefficient. On average, the estimated dental age overestimated chronological age by only around 1 month in both females and males. The Intraclass correlation coefficient values were 0.99 for both sexes, suggesting excellent reliability of the method. Reference dataset for dental age estimation developed on the basis of southern Chinese was applicable for use among the northern Chinese.

  4. A method to estimate stellar ages from kinematical data

    Science.gov (United States)

    Almeida-Fernandes, F.; Rocha-Pinto, H. J.

    2018-05-01

    We present a method to build a probability density function (PDF) for the age of a star based on its peculiar velocities U, V, and W and its orbital eccentricity. The sample used in this work comes from the Geneva-Copenhagen Survey (GCS) that contains the spatial velocities, orbital eccentricities, and isochronal ages for about 14 000 stars. Using the GCS stars, we fitted the parameters that describe the relations between the distributions of kinematical properties and age. This parametrization allows us to obtain an age probability from the kinematical data. From this age PDF, we estimate an individual average age for the star using the most likely age and the expected age. We have obtained the stellar age PDF for the age of 9102 stars from the GCS and have shown that the distribution of individual ages derived from our method is in good agreement with the distribution of isochronal ages. We also observe a decline in the mean metallicity with our ages for stars younger than 7 Gyr, similar to the one observed for isochronal ages. This method can be useful for the estimation of rough stellar ages for those stars that fall in areas of the Hertzsprung-Russell diagram where isochrones are tightly crowded. As an example of this method, we estimate the age of Trappist-1, which is a M8V star, obtaining the age of t(UVW) = 12.50(+0.29 - 6.23) Gyr.

  5. The fossilized birth–death process for coherent calibration of divergence-time estimates

    Science.gov (United States)

    Heath, Tracy A.; Huelsenbeck, John P.; Stadler, Tanja

    2014-01-01

    Time-calibrated species phylogenies are critical for addressing a wide range of questions in evolutionary biology, such as those that elucidate historical biogeography or uncover patterns of coevolution and diversification. Because molecular sequence data are not informative on absolute time, external data—most commonly, fossil age estimates—are required to calibrate estimates of species divergence dates. For Bayesian divergence time methods, the common practice for calibration using fossil information involves placing arbitrarily chosen parametric distributions on internal nodes, often disregarding most of the information in the fossil record. We introduce the “fossilized birth–death” (FBD) process—a model for calibrating divergence time estimates in a Bayesian framework, explicitly acknowledging that extant species and fossils are part of the same macroevolutionary process. Under this model, absolute node age estimates are calibrated by a single diversification model and arbitrary calibration densities are not necessary. Moreover, the FBD model allows for inclusion of all available fossils. We performed analyses of simulated data and show that node age estimation under the FBD model results in robust and accurate estimates of species divergence times with realistic measures of statistical uncertainty, overcoming major limitations of standard divergence time estimation methods. We used this model to estimate the speciation times for a dataset composed of all living bears, indicating that the genus Ursus diversified in the Late Miocene to Middle Pliocene. PMID:25009181

  6. Age estimation using exfoliative cytology and radiovisiography: A comparative study.

    Science.gov (United States)

    Nallamala, Shilpa; Guttikonda, Venkateswara Rao; Manchikatla, Praveen Kumar; Taneeru, Sravya

    2017-01-01

    Age estimation is one of the essential factors in establishing the identity of an individual. Among various methods, exfoliative cytology (EC) is a unique, noninvasive technique, involving simple, and pain-free collection of intact cells from the oral cavity for microscopic examination. The study was undertaken with an aim to estimate the age of an individual from the average cell size of their buccal smears calculated using image analysis morphometric software and the pulp-tooth area ratio in mandibular canine of the same individual using radiovisiography (RVG). Buccal smears were collected from 100 apparently healthy individuals. After fixation in 95% alcohol, the smears were stained using Papanicolaou stain. The average cell size was measured using image analysis software (Image-Pro Insight 8.0). The RVG images of mandibular canines were obtained, pulp and tooth areas were traced using AutoCAD 2010 software, and area ratio was calculated. The estimated age was then calculated using regression analysis. The paired t -test between chronological age and estimated age by cell size and pulp-tooth area ratio was statistically nonsignificant ( P > 0.05). In the present study, age estimated by pulp-tooth area ratio and EC yielded good results.

  7. Trends in absolute socioeconomic inequalities in mortality in Sweden and New Zealand. A 20-year gender perspective

    Directory of Open Access Journals (Sweden)

    Blakely Tony

    2006-06-01

    Full Text Available Abstract Background Both trends in socioeconomic inequalities in mortality, and cross-country comparisons, may give more information about the causes of health inequalities. We analysed trends in socioeconomic differentials by mortality from early 1980s to late 1990s, comparing Sweden with New Zealand. Methods The New Zealand Census Mortality Study (NZCMS consisting of over 2 million individuals and the Swedish Survey of Living Conditions (ULF comprising over 100, 000 individuals were used for analyses. Education and household income were used as measures of socioeconomic position (SEP. The slope index of inequality (SII was calculated to estimate absolute inequalities in mortality. Analyses were based on 3–5 year follow-up and limited to individuals aged 25–77 years. Age standardised mortality rates were calculated using the European population standard. Results Absolute inequalities in mortality on average over the 1980s and 1990s for both men and women by education were similar in Sweden and New Zealand, but by income were greater in Sweden. Comparing trends in absolute inequalities over the 1980s and 1990s, men's absolute inequalities by education decreased by 66% in Sweden and by 17% in New Zealand (p for trend Conclusion Trends in socioeconomic inequalities in mortality were clearly most favourable for men in Sweden. Trends also seemed to be more favourable for men than women in New Zealand. Assuming the trends in male inequalities in Sweden were not a statistical chance finding, it is not clear what the substantive reason(s was for the pronounced decrease. Further gender comparisons are required.

  8. Relationship between LIBS Ablation and Pit Volume for Geologic Samples: Applications for in situ Absolute Geochronology

    Science.gov (United States)

    Devismes, D.; Cohen, Barbara A.

    2014-01-01

    In planetary sciences, in situ absolute geochronology is a scientific and engineering challenge. Currently, the age of the Martian surface can only be determined by crater density counting. However this method has significant uncertainties and needs to be calibrated with absolute ages. We are developing an instrument to acquire in situ absolute geochronology based on the K-Ar method. The protocol is based on the laser ablation of a rock by hundreds of laser pulses. Laser Induced Breakdown Spectroscopy (LIBS) gives the potassium content of the ablated material and a mass spectrometer (quadrupole or ion trap) measures the quantity of 40Ar released. In order to accurately measure the quantity of released 40Ar in cases where Ar is an atmospheric constituent (e.g., Mars), the sample is first put into a chamber under high vacuum. The 40Arquantity, the concentration of K and the estimation of the ablated mass are the parameters needed to give the age of the rocks. The main uncertainties with this method are directly linked to the measures of the mass (typically some µg) and of the concentration of K by LIBS (up to 10%). Because the ablated mass is small compared to the mass of the sample, and because material is redeposited onto the sample after ablation, it is not possible to directly measure the ablated mass. Our current protocol measures the ablated volume and estimates the sample density to calculate ablated mass. The precision and accuracy of this method may be improved by using knowledge of the sample's geologic properties to predict its response to laser ablation, i.e., understanding whether natural samples have a predictable relationship between laser energy deposited and resultant ablation volume. In contrast to most previous studies of laser ablation, theoretical equations are not highly applicable. The reasons are numerous, but the most important are: a) geologic rocks are complex, polymineralic materials; b) the conditions of ablation are unusual (for example

  9. The Prevalence of Age-Related Eye Diseases and Visual Impairment in Aging: Current Estimates

    Science.gov (United States)

    Klein, Ronald; Klein, Barbara E. K.

    2013-01-01

    Purpose. To examine prevalence of five age-related eye conditions (age-related cataract, AMD, open-angle glaucoma, diabetic retinopathy [DR], and visual impairment) in the United States. Methods. Review of published scientific articles and unpublished research findings. Results. Cataract, AMD, open-angle glaucoma, DR, and visual impairment prevalences are high in four different studies of these conditions, especially in people over 75 years of age. There are disparities among racial/ethnic groups with higher age-specific prevalence of DR, open-angle glaucoma, and visual impairment in Hispanics and blacks compared with whites, higher prevalence of age-related cataract in whites compared with blacks, and higher prevalence of late AMD in whites compared with Hispanics and blacks. The estimates are based on old data and do not reflect recent changes in the distribution of age and race/ethnicity in the United States population. There are no epidemiologic estimates of prevalence for many visually-impairing conditions. Conclusions. Ongoing prevalence surveys designed to provide reliable estimates of visual impairment, AMD, age-related cataract, open-angle glaucoma, and DR are needed. It is important to collect objective data on these and other conditions that affect vision and quality of life in order to plan for health care needs and identify areas for further research. PMID:24335069

  10. Encasing the Absolutes

    Directory of Open Access Journals (Sweden)

    Uroš Martinčič

    2014-05-01

    Full Text Available The paper explores the issue of structure and case in English absolute constructions, whose subjects are deduced by several descriptive grammars as being in the nominative case due to its supposed neutrality in terms of register. This deduction is countered by systematic accounts presented within the framework of the Minimalist Program which relate the case of absolute constructions to specific grammatical factors. Each proposal is shown as an attempt of analysing absolute constructions as basic predication structures, either full clauses or small clauses. I argue in favour of the small clause approach due to its minimal reliance on transformations and unique stipulations. Furthermore, I propose that small clauses project a singular category, and show that the use of two cases in English absolute constructions can be accounted for if they are analysed as depictive phrases, possibly selected by prepositions. The case of the subject in absolutes is shown to be a result of syntactic and non-syntactic factors. I thus argue in accordance with Minimalist goals that syntactic case does not exist, attributing its role in absolutes to other mechanisms.

  11. Age estimation of burbot using pectoral fin rays, brachiostegal rays, and otoliths

    Science.gov (United States)

    Klein, Zachary B.; Terrazas, Marc M.; Quist, Michael C.

    2014-01-01

    Throughout much of its native distribution, burbot (Lota lota) is a species of conservation concern. Understanding dynamic rate functions is critical for the effective management of sensitive burbot populations, which necessitates accurate and precise age estimates. Managing sensitive burbot populations requires an accurate and precise non-lethal alternative. In an effort to identify a non-lethal ageing structure, we compared the precision of age estimates obtained from otoliths, pectoral fin rays, dorsal fin rays and branchiostegal rays from 208 burbot collected from the Green River drainage, Wyoming. Additionally, we compared the accuracy of age estimates from pectoral fin rays, dorsal fin rays and branchiostegal rays to those of otoliths. Dorsal fin rays were immediately deemed a poor ageing structure and removed from further analysis. Age-bias plots of consensus ages derived from branchiostegal rays and pectoral fin rays were appreciably different from those obtained from otoliths. Exact agreement between readers and reader confidence was highest for otoliths and lowest for branchiostegal rays. Age-bias plots indicated that age estimates obtained from branchiostegal rays and pectoral fin rays were substantially different from age estimates obtained from otoliths. Our results indicate that otoliths provide the most precise age estimates for burbot.

  12. Accuracy and precision of estimating age of gray wolves by tooth wear

    Science.gov (United States)

    Gipson, P.S.; Ballard, W.B.; Nowak, R.M.; Mech, L.D.

    2000-01-01

    We evaluated the accuracy and precision of tooth wear for aging gray wolves (Canis lupus) from Alaska, Minnesota, and Ontario based on 47 known-age or known-minimum-age skulls. Estimates of age using tooth wear and a commercial cementum annuli-aging service were useful for wolves up to 14 years old. The precision of estimates from cementum annuli was greater than estimates from tooth wear, but tooth wear estimates are more applicable in the field. We tended to overestimate age by 1-2 years and occasionally by 3 or 4 years. The commercial service aged young wolves with cementum annuli to within ?? 1 year of actual age, but under estimated ages of wolves ???9 years old by 1-3 years. No differences were detected in tooth wear patterns for wild wolves from Alaska, Minnesota, and Ontario, nor between captive and wild wolves. Tooth wear was not appropriate for aging wolves with an underbite that prevented normal wear or severely broken and missing teeth.

  13. Applications of physiological bases of ageing to forensic sciences. Estimation of age-at-death.

    Science.gov (United States)

    C Zapico, Sara; Ubelaker, Douglas H

    2013-03-01

    Age-at-death estimation is one of the main challenges in forensic sciences since it contributes to the identification of individuals. There are many anthropological techniques to estimate the age at death in children and adults. However, in adults this methodology is less accurate and requires population specific references. For that reason, new methodologies have been developed. Biochemical methods are based on the natural process of ageing, which induces different biochemical changes that lead to alterations in cells and tissues. In this review, we describe different attempts to estimate the age in adults based on these changes. Chemical approaches imply modifications in molecules or accumulation of some products. Molecular biology approaches analyze the modifications in DNA and chromosomes. Although the most accurate technique appears to be aspartic acid racemization, it is important to take into account the other techniques because the forensic context and the human remains available will determine the possibility to apply one or another methodology. Copyright © 2013 Elsevier B.V. All rights reserved.

  14. Towards absolute neutrino masses

    Energy Technology Data Exchange (ETDEWEB)

    Vogel, Petr [Kellogg Radiation Laboratory 106-38, Caltech, Pasadena, CA 91125 (United States)

    2007-06-15

    Various ways of determining the absolute neutrino masses are briefly reviewed and their sensitivities compared. The apparent tension between the announced but unconfirmed observation of the 0{nu}{beta}{beta} decay and the neutrino mass upper limit based on observational cosmology is used as an example of what could happen eventually. The possibility of a 'nonstandard' mechanism of the 0{nu}{beta}{beta} decay is stressed and the ways of deciding which of the possible mechanisms is actually operational are described. The importance of the 0{nu}{beta}{beta} nuclear matrix elements is discussed and their uncertainty estimated.

  15. Re-evaluating neonatal-age models for ungulates: does model choice affect survival estimates?

    Directory of Open Access Journals (Sweden)

    Troy W Grovenburg

    Full Text Available New-hoof growth is regarded as the most reliable metric for predicting age of newborn ungulates, but variation in estimated age among hoof-growth equations that have been developed may affect estimates of survival in staggered-entry models. We used known-age newborns to evaluate variation in age estimates among existing hoof-growth equations and to determine the consequences of that variation on survival estimates. During 2001-2009, we captured and radiocollared 174 newborn (≤24-hrs old ungulates: 76 white-tailed deer (Odocoileus virginianus in Minnesota and South Dakota, 61 mule deer (O. hemionus in California, and 37 pronghorn (Antilocapra americana in South Dakota. Estimated age of known-age newborns differed among hoof-growth models and varied by >15 days for white-tailed deer, >20 days for mule deer, and >10 days for pronghorn. Accuracy (i.e., the proportion of neonates assigned to the correct age in aging newborns using published equations ranged from 0.0% to 39.4% in white-tailed deer, 0.0% to 3.3% in mule deer, and was 0.0% for pronghorns. Results of survival modeling indicated that variability in estimates of age-at-capture affected short-term estimates of survival (i.e., 30 days for white-tailed deer and mule deer, and survival estimates over a longer time frame (i.e., 120 days for mule deer. Conversely, survival estimates for pronghorn were not affected by estimates of age. Our analyses indicate that modeling survival in daily intervals is too fine a temporal scale when age-at-capture is unknown given the potential inaccuracies among equations used to estimate age of neonates. Instead, weekly survival intervals are more appropriate because most models accurately predicted ages within 1 week of the known age. Variation among results of neonatal-age models on short- and long-term estimates of survival for known-age young emphasizes the importance of selecting an appropriate hoof-growth equation and appropriately defining intervals (i

  16. Absolute age determination of quaternary faults

    International Nuclear Information System (INIS)

    Cheong, Chang Sik; Lee, Seok Hoon; Choi, Man Sik

    2000-03-01

    To constrain the age of neotectonic fault movement, Rb-Sr, K-Ar, U-series disequilibrium, C-14 and Be-10 methods were applied to the fault gouges, fracture infillings and sediments from the Malbang, Ipsil, Wonwonsa faults faults in the Ulsan fault zone, Yangsan fault in the Yeongdeog area and southeastern coastal area. Rb-Sr and K-Ar data imply that the fault movement of the Ulan fault zone initiated at around 30 Ma and preliminary dating result for the Yang san fault is around 70 Ma in the Yeongdeog area. K-Ar and U-series disequilibrium dating results for fracture infillings in the Ipsil fault are consistent with reported ESR ages. Radiocarbon ages of quaternary sediments from the Jeongjari area are discordant with stratigraphic sequence. Carbon isotope data indicate a difference of sedimentry environment for those samples. Be-10 dating results for the Suryum fault area are consistent with reported OSL results

  17. Absolute age determination of quaternary faults

    Energy Technology Data Exchange (ETDEWEB)

    Cheong, Chang Sik; Lee, Seok Hoon; Choi, Man Sik [Korea Basic Science Institute, Seoul (Korea, Republic of)] (and others)

    2000-03-15

    To constrain the age of neotectonic fault movement, Rb-Sr, K-Ar, U-series disequilibrium, C-14 and Be-10 methods were applied to the fault gouges, fracture infillings and sediments from the Malbang, Ipsil, Wonwonsa faults faults in the Ulsan fault zone, Yangsan fault in the Yeongdeog area and southeastern coastal area. Rb-Sr and K-Ar data imply that the fault movement of the Ulan fault zone initiated at around 30 Ma and preliminary dating result for the Yang san fault is around 70 Ma in the Yeongdeog area. K-Ar and U-series disequilibrium dating results for fracture infillings in the Ipsil fault are consistent with reported ESR ages. Radiocarbon ages of quaternary sediments from the Jeongjari area are discordant with stratigraphic sequence. Carbon isotope data indicate a difference of sedimentry environment for those samples. Be-10 dating results for the Suryum fault area are consistent with reported OSL results.

  18. Absolute advantage

    NARCIS (Netherlands)

    J.G.M. van Marrewijk (Charles)

    2008-01-01

    textabstractA country is said to have an absolute advantage over another country in the production of a good or service if it can produce that good or service using fewer real resources. Equivalently, using the same inputs, the country can produce more output. The concept of absolute advantage can

  19. Validating the absolute reliability of a fat free mass estimate equation in hemodialysis patients using near-infrared spectroscopy.

    Science.gov (United States)

    Kono, Kenichi; Nishida, Yusuke; Moriyama, Yoshihumi; Taoka, Masahiro; Sato, Takashi

    2015-06-01

    The assessment of nutritional states using fat free mass (FFM) measured with near-infrared spectroscopy (NIRS) is clinically useful. This measurement should incorporate the patient's post-dialysis weight ("dry weight"), in order to exclude the effects of any change in water mass. We therefore used NIRS to investigate the regression, independent variables, and absolute reliability of FFM in dry weight. The study included 47 outpatients from the hemodialysis unit. Body weight was measured before dialysis, and FFM was measured using NIRS before and after dialysis treatment. Multiple regression analysis was used to estimate the FFM in dry weight as the dependent variable. The measured FFM before dialysis treatment (Mw-FFM), and the difference between measured and dry weight (Mw-Dw) were independent variables. We performed Bland-Altman analysis to detect errors between the statistically estimated FFM and the measured FFM after dialysis treatment. The multiple regression equation to estimate the FFM in dry weight was: Dw-FFM = 0.038 + (0.984 × Mw-FFM) + (-0.571 × [Mw-Dw]); R(2)  = 0.99). There was no systematic bias between the estimated and the measured values of FFM in dry weight. Using NIRS, FFM in dry weight can be calculated by an equation including FFM in measured weight and the difference between the measured weight and the dry weight. © 2015 The Authors. Therapeutic Apheresis and Dialysis © 2015 International Society for Apheresis.

  20. Age Estimation Robust to Optical and Motion Blurring by Deep Residual CNN

    Directory of Open Access Journals (Sweden)

    Jeon Seong Kang

    2018-04-01

    Full Text Available Recently, real-time human age estimation based on facial images has been applied in various areas. Underneath this phenomenon lies an awareness that age estimation plays an important role in applying big data to target marketing for age groups, product demand surveys, consumer trend analysis, etc. However, in a real-world environment, various optical and motion blurring effects can occur. Such effects usually cause a problem in fully capturing facial features such as wrinkles, which are essential to age estimation, thereby degrading accuracy. Most of the previous studies on age estimation were conducted for input images almost free from blurring effect. To overcome this limitation, we propose the use of a deep ResNet-152 convolutional neural network for age estimation, which is robust to various optical and motion blurring effects of visible light camera sensors. We performed experiments with various optical and motion blurred images created from the park aging mind laboratory (PAL and craniofacial longitudinal morphological face database (MORPH databases, which are publicly available. According to the results, the proposed method exhibited better age estimation performance than the previous methods.

  1. On the absolute meaning of motion

    Directory of Open Access Journals (Sweden)

    H. Edwards

    Full Text Available The present manuscript aims to clarify why motion causes matter to age slower in a comparable sense, and how this relates to relativistic effects caused by motion. A fresh analysis of motion, build on first axiom, delivers proof with its result, from which significant new understanding and computational power is gained.A review of experimental results demonstrates, that unaccelerated motion causes matter to age slower in a comparable, observer independent sense. Whilst focusing on this absolute effect, the present manuscript clarifies its context to relativistic effects, detailing their relationship and incorporating both into one consistent picture. The presented theoretical results make new predictions and are testable through suggested experiment of a novel nature. The manuscript finally arrives at an experimental tool and methodology, which as far as motion in ungravitated space is concerned or gravity appreciated, enables us to find the absolute observer independent picture of reality, which is reflected in the comparable display of atomic clocks.The discussion of the theoretical results, derives a physical causal understanding of gravity, a mathematical formulation of which, will be presented. Keywords: Kinematics, Gravity, Atomic clocks, Cosmic microwave background

  2. Coronal pulp biomarker: A lesser known age estimation modality

    Directory of Open Access Journals (Sweden)

    Smrithi D Veera

    2014-01-01

    Full Text Available Introduction: The evolving state of art digital technology currently available is opening new avenues in forensic odontology for age estimation methods which are subject to debate in terms of accuracy and precision. A study was carried to analyze efficacy and practical application for age estimation using digital panoramic radiographs on South Indian population. Aims and Objectives: 1. To study reduction of coronal pulp chamber using Tooth Coronal Index (TCI on panoramic radiographs and correlate with chronologic age. 2. To establish accuracy of digital panoramic radiographs as a simple, non-invasive tool. Materials and Methods: The study illustrates the potential value of a little known aging method. The study groups comprised a total of 100 subjects of both sexes in age range of 20 and 60 years each who were subjected to panoramic radiography. A panoramic radiographic examination using digital panoramic machine was conducted on selected individuals. The TCI was calibrated using AGFA computer software for accuracy and precision. The values obtained were subjected to regression analysis, results calculated and correlated with chronologic age. In the present study a population of known age was studied and subjected to digital panoramic radiographic examination. The correlation between reduction of coronal pulp cavity and chronological age was examined. TCI was computed for each tooth and regressed on real age. Statistical Analysis Used: Pearson correlation co-efficient was used to find the significance of relationship between age and TCI. Regression analysis has been used for predicting age using TCI for premolar and molar. Inaccuracy and bias have been determined to assess the precision of prediction equations. Results and Conclusion: Prediction potential of TCI comes down for ages above 50 years and is comfortably good below 50 years without much difference between premolars and molars. This study demonstrates the potential value of TCI for age

  3. Relative and absolute poverty : the case of México, 1992-2004

    OpenAIRE

    Ruiz-Castillo, Javier

    2005-01-01

    This paper advocates that although an absolute notion of poverty should remain an essential ingredient in the evaluation of the standard of living in developing and transition economies, it is time that relative poverty begins to be systematically estimated for those same economies. This prescription is applied to México for the 1992-2004 period, where the Fox Administration has fixed for the first time an absolute poverty line for 2000. To facilitate comparisons with developed countries, the...

  4. Absolutely relative or relatively absolute: violations of value invariance in human decision making.

    Science.gov (United States)

    Teodorescu, Andrei R; Moran, Rani; Usher, Marius

    2016-02-01

    Making decisions based on relative rather than absolute information processing is tied to choice optimality via the accumulation of evidence differences and to canonical neural processing via accumulation of evidence ratios. These theoretical frameworks predict invariance of decision latencies to absolute intensities that maintain differences and ratios, respectively. While information about the absolute values of the choice alternatives is not necessary for choosing the best alternative, it may nevertheless hold valuable information about the context of the decision. To test the sensitivity of human decision making to absolute values, we manipulated the intensities of brightness stimuli pairs while preserving either their differences or their ratios. Although asked to choose the brighter alternative relative to the other, participants responded faster to higher absolute values. Thus, our results provide empirical evidence for human sensitivity to task irrelevant absolute values indicating a hard-wired mechanism that precedes executive control. Computational investigations of several modelling architectures reveal two alternative accounts for this phenomenon, which combine absolute and relative processing. One account involves accumulation of differences with activation dependent processing noise and the other emerges from accumulation of absolute values subject to the temporal dynamics of lateral inhibition. The potential adaptive role of such choice mechanisms is discussed.

  5. Using a Novel Absolute Ontogenetic Age Determination Technique to Calculate the Timing of Tooth Eruption in the Saber-Toothed Cat, Smilodon fatalis.

    Directory of Open Access Journals (Sweden)

    M Aleksander Wysocki

    Full Text Available Despite the superb fossil record of the saber-toothed cat, Smilodon fatalis, ontogenetic age determination for this and other ancient species remains a challenge. The present study utilizes a new technique, a combination of data from stable oxygen isotope analyses and micro-computed tomography, to establish the eruption rate for the permanent upper canines in Smilodon fatalis. The results imply an eruption rate of 6.0 millimeters per month, which is similar to a previously published average enamel growth rate of the S. fatalis upper canines (5.8 millimeters per month. Utilizing the upper canine growth rate, the upper canine eruption rate, and a previously published tooth replacement sequence, this study calculates absolute ontogenetic age ranges of tooth development and eruption in S. fatalis. The timing of tooth eruption is compared between S. fatalis and several extant conical-toothed felids, such as the African lion (Panthera leo. Results suggest that the permanent dentition of S. fatalis, except for the upper canines, was fully erupted by 14 to 22 months, and that the upper canines finished erupting at about 34 to 41 months. Based on these developmental age calculations, S. fatalis individuals less than 4 to 7 months of age were not typically preserved at Rancho La Brea. On the whole, S. fatalis appears to have had delayed dental development compared to dental development in similar-sized extant felids. This technique for absolute ontogenetic age determination can be replicated in other ancient species, including non-saber-toothed taxa, as long as the timing of growth initiation and growth rate can be determined for a specific feature, such as a tooth, and that growth period overlaps with the development of the other features under investigation.

  6. Using a Novel Absolute Ontogenetic Age Determination Technique to Calculate the Timing of Tooth Eruption in the Saber-Toothed Cat, Smilodon fatalis.

    Science.gov (United States)

    Wysocki, M Aleksander; Feranec, Robert S; Tseng, Zhijie Jack; Bjornsson, Christopher S

    2015-01-01

    Despite the superb fossil record of the saber-toothed cat, Smilodon fatalis, ontogenetic age determination for this and other ancient species remains a challenge. The present study utilizes a new technique, a combination of data from stable oxygen isotope analyses and micro-computed tomography, to establish the eruption rate for the permanent upper canines in Smilodon fatalis. The results imply an eruption rate of 6.0 millimeters per month, which is similar to a previously published average enamel growth rate of the S. fatalis upper canines (5.8 millimeters per month). Utilizing the upper canine growth rate, the upper canine eruption rate, and a previously published tooth replacement sequence, this study calculates absolute ontogenetic age ranges of tooth development and eruption in S. fatalis. The timing of tooth eruption is compared between S. fatalis and several extant conical-toothed felids, such as the African lion (Panthera leo). Results suggest that the permanent dentition of S. fatalis, except for the upper canines, was fully erupted by 14 to 22 months, and that the upper canines finished erupting at about 34 to 41 months. Based on these developmental age calculations, S. fatalis individuals less than 4 to 7 months of age were not typically preserved at Rancho La Brea. On the whole, S. fatalis appears to have had delayed dental development compared to dental development in similar-sized extant felids. This technique for absolute ontogenetic age determination can be replicated in other ancient species, including non-saber-toothed taxa, as long as the timing of growth initiation and growth rate can be determined for a specific feature, such as a tooth, and that growth period overlaps with the development of the other features under investigation.

  7. The fading American dream: Trends in absolute income mobility since 1940.

    Science.gov (United States)

    Chetty, Raj; Grusky, David; Hell, Maximilian; Hendren, Nathaniel; Manduca, Robert; Narang, Jimmy

    2017-04-28

    We estimated rates of "absolute income mobility"-the fraction of children who earn more than their parents-by combining data from U.S. Census and Current Population Survey cross sections with panel data from de-identified tax records. We found that rates of absolute mobility have fallen from approximately 90% for children born in 1940 to 50% for children born in the 1980s. Increasing Gross Domestic Product (GDP) growth rates alone cannot restore absolute mobility to the rates experienced by children born in the 1940s. However, distributing current GDP growth more equally across income groups as in the 1940 birth cohort would reverse more than 70% of the decline in mobility. These results imply that reviving the "American dream" of high rates of absolute mobility would require economic growth that is shared more broadly across the income distribution. Copyright © 2017, American Association for the Advancement of Science.

  8. Human Age Estimation Method Robust to Camera Sensor and/or Face Movement

    Directory of Open Access Journals (Sweden)

    Dat Tien Nguyen

    2015-08-01

    Full Text Available Human age can be employed in many useful real-life applications, such as customer service systems, automatic vending machines, entertainment, etc. In order to obtain age information, image-based age estimation systems have been developed using information from the human face. However, limitations exist for current age estimation systems because of the various factors of camera motion and optical blurring, facial expressions, gender, etc. Motion blurring can usually be presented on face images by the movement of the camera sensor and/or the movement of the face during image acquisition. Therefore, the facial feature in captured images can be transformed according to the amount of motion, which causes performance degradation of age estimation systems. In this paper, the problem caused by motion blurring is addressed and its solution is proposed in order to make age estimation systems robust to the effects of motion blurring. Experiment results show that our method is more efficient for enhancing age estimation performance compared with systems that do not employ our method.

  9. Absolute Risk Aversion and the Returns to Education.

    Science.gov (United States)

    Brunello, Giorgio

    2002-01-01

    Uses 1995 Italian household income and wealth survey to measure individual absolute risk aversion of 1,583 married Italian male household heads. Uses this measure as an instrument for attained education in a standard-log earnings equation. Finds that the IV estimate of the marginal return to schooling is much higher than the ordinary least squares…

  10. Aspartic acid racemisation in purified elastin from arteries as basis for age estimation.

    Science.gov (United States)

    Dobberstein, R C; Tung, S-M; Ritz-Timme, S

    2010-07-01

    Aspartic acid racemisation (AAR) results in an age-dependent accumulation of D: -aspartic acid in durable human proteins and can be used as a basis for age estimation. Routinely, age estimation based on AAR is performed by analysis of dentine. However, in forensic practise, teeth are not always available. Non-dental tissues for age estimation may be suitable for age estimation based on AAR if they contain durable proteins that can be purified and analysed. Elastin is such a durable protein. To clarify if purified elastin from arteries is a suitable sample for biochemical age estimation, AAR was determined in purified elastin from arteries from individuals of known age (n = 68 individuals, including n = 15 putrefied corpses), considering the influence of different stages of atherosclerosis and putrefaction on the AAR values. AAR was found to increase with age. The relationship between AAR and age was good enough to serve as basis for age estimation, but worse than known from dentinal proteins. Intravital and post-mortem degradation of elastin may have a moderate effect on the AAR values. Age estimation based on AAR in purified elastin from arteries may be a valuable additional tool in the identification of unidentified cadavers, especially in cases where other methods cannot be applied (e.g., no available teeth and body parts).

  11. Estimation of age structure of fish populations from length-frequency data

    International Nuclear Information System (INIS)

    Kumar, K.D.; Adams, S.M.

    1977-01-01

    A probability model is presented to determine the age structure of a fish population from length-frequency data. It is shown that when the age-length key is available, maximum-likelihood estimates of the age structure can be obtained. When the key is not available, approximate estimates of the age structure can be obtained. The model is used for determination of the age structure of populations of channel catfish and white crappie. Practical applications of the model to impact assessment are discussed

  12. Age Spreads and the Temperature Dependence of Age Estimates in Upper Sco

    Energy Technology Data Exchange (ETDEWEB)

    Fang Qiliang; Herczeg, Gregory J. [Kavli Institute for Astronomy and Astrophysics, Peking University, Yiheyuan Lu 5, Haidian Qu, 100871 Beijing (China); Rizzuto, Aaron [Department of Astronomy, University of Texas, 2515 Speedway, Stop C1400, Austin, TX 78712 (United States)

    2017-06-20

    Past estimates for the age of the Upper Sco Association are typically 11–13 Myr for intermediate-mass stars and 4–5 Myr for low-mass stars. In this study, we simulate populations of young stars to investigate whether this apparent dependence of estimated age on spectral type may be explained by the star formation history of the association. Solar and intermediate mass stars begin their pre-main sequence evolution on the Hayashi track, with fully convective interiors and cool photospheres. Intermediate-mass stars quickly heat up and transition onto the radiative Henyey track. As a consequence, for clusters in which star formation occurs on a timescale similar to that of the transition from a convective to a radiative interior, discrepancies in ages will arise when ages are calculated as a function of temperature instead of mass. Simple simulations of a cluster with constant star formation over several Myr may explain about half of the difference in inferred ages versus photospheric temperature; speculative constructions that consist of a constant star formation followed by a large supernova-driven burst could fully explain the differences, including those between F and G stars where evolutionary tracks may be more accurate. The age spreads of low-mass stars predicted from these prescriptions for star formation are consistent with the observed luminosity spread of Upper Sco. The conclusion that a lengthy star formation history will yield a temperature dependence in ages is expected from the basic physics of pre-main sequence evolution, and is qualitatively robust to the large uncertainties in pre-main sequence evolutionary models.

  13. Is Greulich–Pyle age estimation applicable for determining maturation in male Africans?

    Directory of Open Access Journals (Sweden)

    Alan G. Morri

    2012-09-01

    Full Text Available Skeletal age estimation as a means of assessing development and skeletal maturation in children and adolescents is of great importance for clinical and forensic purposes. The skeletal age of a test population is estimated by comparison with established standards, the most common standards being those in the Radiographic atlas of skeletal development of the hand and wristpublished by Greulich and Pyle in 1959. These standards are based on the assumption that skeletal maturity in male individuals is attained by the chronological age of 19 years. Although they have been widely tested, the applicability of these standards to contemporary populations has yet to be tested on a population of African biological origin living in South Africa. We therefore estimated the skeletal age of 131 male Africans aged between 13 and 21 years, using the Greulich–Pyle method which we applied to pre-existing hand–wrist radiographs. Estimated skeletal age was compared to the known chronological age for each radiograph. Skeletal age was on average approximately 6 months younger than chronological age. The Greulich–Pyle method underestimated skeletal age for approximately 74%of the sample and overestimated skeletal age for 26%of the sample. Skeletal maturity as characterised by complete epiphyseal fusion occurred approximately 2.1 years later than Greulich and Pyle’s estimate of 19 years. Thus skeletal maturation was still in progress in a large proportion of the 20- and 21-year-old individuals in our study. The Greulich–Pyle method showed high precision but low accuracy and was therefore not directly applicable to African male individuals. Formulation of skeletal age estimation standards specific to South African populations is therefore recommended.

  14. Age and gender estimation using Region-SIFT and multi-layered SVM

    Science.gov (United States)

    Kim, Hyunduk; Lee, Sang-Heon; Sohn, Myoung-Kyu; Hwang, Byunghun

    2018-04-01

    In this paper, we propose an age and gender estimation framework using the region-SIFT feature and multi-layered SVM classifier. The suggested framework entails three processes. The first step is landmark based face alignment. The second step is the feature extraction step. In this step, we introduce the region-SIFT feature extraction method based on facial landmarks. First, we define sub-regions of the face. We then extract SIFT features from each sub-region. In order to reduce the dimensions of features we employ a Principal Component Analysis (PCA) and a Linear Discriminant Analysis (LDA). Finally, we classify age and gender using a multi-layered Support Vector Machines (SVM) for efficient classification. Rather than performing gender estimation and age estimation independently, the use of the multi-layered SVM can improve the classification rate by constructing a classifier that estimate the age according to gender. Moreover, we collect a dataset of face images, called by DGIST_C, from the internet. A performance evaluation of proposed method was performed with the FERET database, CACD database, and DGIST_C database. The experimental results demonstrate that the proposed approach classifies age and performs gender estimation very efficiently and accurately.

  15. Age Estimation of African Lions Panthera leo by Ratio of Tooth Areas.

    Science.gov (United States)

    White, Paula A; Ikanda, Dennis; Ferrante, Luigi; Chardonnet, Philippe; Mesochina, Pascal; Cameriere, Roberto

    2016-01-01

    Improved age estimation of African lions Panthera leo is needed to address a number of pressing conservation issues. Here we present a formula for estimating lion age to within six months of known age based on measuring the extent of pulp closure from X-rays, or Ratio Of tooth AReas (ROAR). Derived from measurements taken from lions aged 3-13 years for which exact ages were known, the formula explains 92% of the total variance. The method of calculating the pulp/tooth area ratio, which has been used extensively in forensic science, is novel in the study of lion aging. As a quantifiable measure, ROAR offers improved lion age estimates for population modeling and investigations of age-related mortality, and may assist national and international wildlife authorities in judging compliance with regulatory measures involving age.

  16. Estimating the formation age distribution of continental crust by unmixing zircon ages

    Science.gov (United States)

    Korenaga, Jun

    2018-01-01

    Continental crust provides first-order control on Earth's surface environment, enabling the presence of stable dry landmasses surrounded by deep oceans. The evolution of continental crust is important for atmospheric evolution, because continental crust is an essential component of deep carbon cycle and is likely to have played a critical role in the oxygenation of the atmosphere. Geochemical information stored in the mineral zircon, known for its resilience to diagenesis and metamorphism, has been central to ongoing debates on the genesis and evolution of continental crust. However, correction for crustal reworking, which is the most critical step when estimating original formation ages, has been incorrectly formulated, undermining the significance of previous estimates. Here I suggest a simple yet promising approach for reworking correction using the global compilation of zircon data. The present-day distribution of crustal formation age estimated by the new "unmixing" method serves as the lower bound to the true crustal growth, and large deviations from growth models based on mantle depletion imply the important role of crustal recycling through the Earth history.

  17. Absolute transition probabilities for 559 strong lines of neutral cerium

    Energy Technology Data Exchange (ETDEWEB)

    Curry, J J, E-mail: jjcurry@nist.go [National Institute of Standards and Technology, Gaithersburg, MD 20899-8422 (United States)

    2009-07-07

    Absolute radiative transition probabilities are reported for 559 strong lines of neutral cerium covering the wavelength range 340-880 nm. These transition probabilities are obtained by scaling published relative line intensities (Meggers et al 1975 Tables of Spectral Line Intensities (National Bureau of Standards Monograph 145)) with a smaller set of published absolute transition probabilities (Bisson et al 1991 J. Opt. Soc. Am. B 8 1545). All 559 new values are for lines for which transition probabilities have not previously been available. The estimated relative random uncertainty of the new data is +-35% for nearly all lines.

  18. The bolometric, infrared and visual absolute magnitudes of Mira variables

    International Nuclear Information System (INIS)

    Robertson, B.S.C.; Feast, M.W.

    1981-01-01

    Statistical parallaxes, as well as stars with individually known distances are used to derive bolometric and infrared absolute magnitudes of Mira (Me) variables. The derived bolometric magnitudes are in the mean about 0.75 mag fainter than recent estimates. The problem of determining the pulsation constant is discussed. Miras with periods greater than 150 days probably pulsate in the first overtone. Those of shorter periods are anomalous and may be fundamental pulsators. It is shown that the absolute visual magnitudes at mean light of Miras with individually determined distances are consistent with values derived by Clayton and Feast from statistical parallaxes. (author)

  19. Age Estimation of African Lions Panthera leo by Ratio of Tooth Areas.

    Directory of Open Access Journals (Sweden)

    Paula A White

    Full Text Available Improved age estimation of African lions Panthera leo is needed to address a number of pressing conservation issues. Here we present a formula for estimating lion age to within six months of known age based on measuring the extent of pulp closure from X-rays, or Ratio Of tooth AReas (ROAR. Derived from measurements taken from lions aged 3-13 years for which exact ages were known, the formula explains 92% of the total variance. The method of calculating the pulp/tooth area ratio, which has been used extensively in forensic science, is novel in the study of lion aging. As a quantifiable measure, ROAR offers improved lion age estimates for population modeling and investigations of age-related mortality, and may assist national and international wildlife authorities in judging compliance with regulatory measures involving age.

  20. Estimating ages of white-tailed deer: Age and sex patterns of error using tooth wear-and-replacement and consistency of cementum annuli

    Science.gov (United States)

    Samuel, Michael D.; Storm, Daniel J.; Rolley, Robert E.; Beissel, Thomas; Richards, Bryan J.; Van Deelen, Timothy R.

    2014-01-01

    The age structure of harvested animals provides the basis for many demographic analyses. Ages of harvested white-tailed deer (Odocoileus virginianus) and other ungulates often are estimated by evaluating replacement and wear patterns of teeth, which is subjective and error-prone. Few previous studies however, examined age- and sex-specific error rates. Counting cementum annuli of incisors is an alternative, more accurate method of estimating age, but factors that influence consistency of cementum annuli counts are poorly known. We estimated age of 1,261 adult (≥1.5 yr old) white-tailed deer harvested in Wisconsin and Illinois (USA; 2005–2008) using both wear-and-replacement and cementum annuli. We compared cementum annuli with wear-and-replacement estimates to assess misclassification rates by sex and age. Wear-and-replacement for estimating ages of white-tailed deer resulted in substantial misclassification compared with cementum annuli. Age classes of females were consistently underestimated, while those of males were underestimated for younger age classes but overestimated for older age classes. Misclassification resulted in an impression of a younger age-structure than actually was the case. Additionally, we obtained paired age-estimates from cementum annuli for 295 deer. Consistency of paired cementum annuli age-estimates decreased with age, was lower in females than males, and decreased as age estimates became less certain. Our results indicated that errors in the wear-and-replacement techniques are substantial and could impact demographic analyses that use age-structure information. 

  1. Absolute beam-charge measurement for single-bunch electron beams

    International Nuclear Information System (INIS)

    Suwada, Tsuyoshi; Ohsawa, Satoshi; Furukawa, Kazuro; Akasaka, Nobumasa

    2000-01-01

    The absolute beam charge of a single-bunch electron beam with a pulse width of 10 ps and that of a short-pulsed electron beam with a pulse width of 1 ns were measured with a Faraday cup in a beam test for the KEK B-Factory (KEKB) injector linac. It is strongly desired to obtain a precise beam-injection rate to the KEKB rings, and to estimate the amount of beam loss. A wall-current monitor was also recalibrated within an error of ±2%. This report describes the new results for an absolute beam-charge measurement for single-bunch and short-pulsed electron beams, and recalibration of the wall-current monitors in detail. (author)

  2. The influence of body size on adult skeletal age estimation methods.

    Science.gov (United States)

    Merritt, Catherine E

    2015-01-01

    Accurate age estimations are essential to archaeological and forensic analyses. However, reliability for adult skeletal age estimations is poor, especially for individuals over the age of 40 years. This is the first study to show that body size influences skeletal age estimation. The İşcan et al., Lovejoy et al., Buckberry and Chamberlain, and Suchey-Brooks age methods were tested on 764 adult skeletons from the Hamann-Todd and William Bass Collections. Statures ranged from 1.30 to 1.93 m and body masses ranged from 24.0 to 99.8 kg. Transition analysis was used to evaluate the differences in the age estimations. For all four methods, the smallest individuals have the lowest ages at transition and the largest individuals have the highest ages at transition. Short and light individuals are consistently underaged, while tall and heavy individuals are consistently overaged. When femoral length and femoral head diameter are compared with the log-age model, results show the same trend as the known stature and body mass measurements. The skeletal remains of underweight individuals have fewer age markers while those of obese individuals have increased surface degeneration and osteophytic lipping. Tissue type and mechanical loading have been shown to affect bone turnover rates, and may explain the differing patterns of skeletal aging. From an archaeological perspective, the underaging of light, short individuals suggests the need to revisit the current research consensus on the young mortality rates of past populations. From a forensic perspective, understanding the influence of body size will impact efforts to identify victims of mass disasters, genocides, and homicides. © 2014 Wiley Periodicals, Inc.

  3. Development of a biometric method to estimate age on hand radiographs.

    Science.gov (United States)

    Remy, Floriane; Hossu, Gabriela; Cendre, Romain; Micard, Emilien; Mainard-Simard, Laurence; Felblinger, Jacques; Martrille, Laurent; Lalys, Loïc

    2017-02-01

    Age estimation of living individuals aged less than 13, 18 or 21 years, which are some relevant legal ages in most European countries, is currently problematic in the forensic context. Thus, numerous methods are available for legal authorities, although their efficiency can be discussed. For those reasons, we aimed to propose a new method, based on the biometric analysis of hand bones. 451 hand radiographs of French individuals under the age of 21 were retrospectively analyzed. This total sample was divided into three subgroups bounded by the relevant legal ages previously mentioned: 0-13, 13-18 and 18-21 years. On these radiographs, we numerically applied the osteometric board method used in anthropology, by including each metacarpal and proximal phalange of the five hand rays in the smallest rectangle possible. In that we can access their length and width information thanks to a measurement protocol developed precisely for our treatment with the ORS Visual ® software. Then, a statistical analysis was performed from these biometric data: a Linear Discriminant Analysis (LDA) evaluated the probability for an individual to belong to one of the age group (0-13, 13-18 or 18-21); and several multivariate regression models were tested for the establishment of age estimation formulas for each of these age groups. The mean Correlation Coefficient between chronological age and both lengths and widths of hand bones is equal to 0.90 for the total sample. Repeatability and reproducibility were assessed. The LDA could more easily predict the belonging to the 0-13 age group. Age can be estimated with a mean standard error which never exceeds 1 year for the 95% confidence interval. Finally, compared to the literature, we can conclude that estimating an age from the biometric information of metacarpals and proximal phalanges is promising. Copyright © 2016. Published by Elsevier B.V.

  4. Absolute age determination of quaternary fault and formation

    Energy Technology Data Exchange (ETDEWEB)

    Cheong, Chang Sik; Lee, Kwang Sik; Choi, Man Sik [Korea Basic Science Institute, Taejon (Korea, Republic of)] (and others)

    2003-03-15

    Rb-Sr and K-Ar dating results for the fault rocks suggest the occurrence of recurrent fault activity around 80-95 Ma, 70 Ma, 50 Ma, 30 Ma and 23 Ma along the Yangsan fault zone. The apparent K-Ar ages tend to be older than Rb-Sr ages, probably indicating the effect of excess radiogenic Ar, which will be furthur investigated by Ar-Ar method. The OSL SAR protocol using 220 .deg. C cut-heat yields reproducible and stratigraphically consistent OSL ages ranging from 71 ka to 48 ka for beach deposits of the marine terrace No 2. The apparent OSL ages for the marine terrace No 3 range from 92 ka to 61 ka. These ages constrain the minimum age of the platform considering the underestimation effect resulted from deposition underwater. Therefore we regard the formation age of the terrace No 3 as MIS(Marine Isotopic Stage) 5c or 5e. Rb-Sr and K-Ar dating results for the fault rocks suggest the occurrence of recurrent fault activity around 40 Ma, 30 Ma and 23 Ma along the Ulsan fault zone. Relatively young (< 10 Ma) fault activities are recognized in the Oesa, Janghangri and Wonwonsa sites.

  5. Using Supervised Deep Learning for Human Age Estimation Problem

    Science.gov (United States)

    Drobnyh, K. A.; Polovinkin, A. N.

    2017-05-01

    Automatic facial age estimation is a challenging task upcoming in recent years. In this paper, we propose using the supervised deep learning features to improve an accuracy of the existing age estimation algorithms. There are many approaches solving the problem, an active appearance model and the bio-inspired features are two of them which showed the best accuracy. For experiments we chose popular publicly available FG-NET database, which contains 1002 images with a broad variety of light, pose, and expression. LOPO (leave-one-person-out) method was used to estimate the accuracy. Experiments demonstrated that adding supervised deep learning features has improved accuracy for some basic models. For example, adding the features to an active appearance model gave the 4% gain (the error decreased from 4.59 to 4.41).

  6. ABSOLUTE NEUTRINO MASSES

    DEFF Research Database (Denmark)

    Schechter, J.; Shahid, M. N.

    2012-01-01

    We discuss the possibility of using experiments timing the propagation of neutrino beams over large distances to help determine the absolute masses of the three neutrinos.......We discuss the possibility of using experiments timing the propagation of neutrino beams over large distances to help determine the absolute masses of the three neutrinos....

  7. The utility of absolute risk prediction using FRAX® and Garvan Fracture Risk Calculator in daily practice.

    Science.gov (United States)

    van Geel, Tineke A C M; Eisman, John A; Geusens, Piet P; van den Bergh, Joop P W; Center, Jacqueline R; Dinant, Geert-Jan

    2014-02-01

    There are two commonly used fracture risk prediction tools FRAX(®) and Garvan Fracture Risk Calculator (GARVAN-FRC). The objective of this study was to investigate the utility of these tools in daily practice. A prospective population-based 5-year follow-up study was conducted in ten general practice centres in the Netherlands. For the analyses, the FRAX(®) and GARVAN-FRC 10-year absolute risks (FRAX(®) does not have 5-year risk prediction) for all fractures were used. Among 506 postmenopausal women aged ≥60 years (mean age: 67.8±5.8 years), 48 (9.5%) sustained a fracture during follow-up. Both tools, using BMD values, distinguish between women who did and did not fracture (10.2% vs. 6.8%, respectively for FRAX(®) and 32.4% vs. 39.1%, respectively for GARVAN-FRC, pbetter for women who sustained a fracture (higher sensitivity) and FRAX(®) for women who did not sustain a fracture (higher specificity). Similar results were obtained using age related cut off points. The discriminant value of both models is at least as good as models used in other medical conditions; hence they can be used to communicate the fracture risk to patients. However, given differences in the estimated risks between FRAX(®) and GARVAN-FRC, the significance of the absolute risk must be related to country-specific recommended intervention thresholds to inform the patient. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  8. Estimating a child's age from an image using whole body proportions.

    Science.gov (United States)

    Lucas, Teghan; Henneberg, Maciej

    2017-09-01

    The use and distribution of child pornography is an increasing problem. Forensic anthropologists are often asked to estimate a child's age from a photograph. Previous studies have attempted to estimate the age of children from photographs using ratios of the face. Here, we propose to include body measurement ratios into age estimates. A total of 1603 boys and 1833 girls aged 5-16 years were measured over a 10-year period. They are 'Cape Coloured' children from South Africa. Their age was regressed on ratios derived from anthropometric measurements of the head as well as the body. Multiple regression equations including four ratios for each sex (head height to shoulder and hip width, knee width, leg length and trunk length) have a standard error of 1.6-1.7 years. The error is of the same order as variation of differences between biological and chronological ages of the children. Thus, the error cannot be minimised any further as it is a direct reflection of a naturally occurring phenomenon.

  9. An overview of age estimation in forensic anthropology: perspectives and practical considerations.

    Science.gov (United States)

    Márquez-Grant, Nicholas

    2015-01-01

    Information on methods of age estimation in physical anthropology, in particular with regard to age-at-death from human skeletal remains, is widely available in the literature. However, the practicalities and real challenges faced in forensic casework are not always highlighted. To provide a practitioner's perspective, regarding age estimation in forensic anthropology (both in the living as well as the dead), with an emphasis on the types of cases, the value of such work and its challenges and limitations. The paper reviews the current literature on age estimation with a focus on forensic anthropology, but it also brings the author's personal perspective derived from a number of forensic cases. Although much is known about what methods to use, but not always how to apply them, little attention has been given in the literature to the real practicalities faced by forensic anthropologists, for example: the challenges in different types of scenarios; how to report age estimations; responsibilities; and ethical concerns. This paper gathers some of these aspects into one overview which includes the value of such work and the practical challenges, not necessarily with the methods themselves, but also with regard to how these are applied in the different cases where age estimation is required.

  10. Dental age estimation using Willems method: A digital orthopantomographic study

    Directory of Open Access Journals (Sweden)

    Rezwana Begum Mohammed

    2014-01-01

    Full Text Available In recent years, age estimation has become increasingly important in living people for a variety of reasons, including identifying criminal and legal responsibility, and for many other social events such as a birth certificate, marriage, beginning a job, joining the army, and retirement. Objectives: The aim of this study was to assess the developmental stages of left seven mandibular teeth for estimation of dental age (DA in different age groups and to evaluate the possible correlation between DA and chronological age (CA in South Indian population using Willems method. Materials and Methods: Digital Orthopantomogram of 332 subjects (166 males, 166 females who fit the study and the criteria were obtained. Assessment of mandibular teeth (from central incisor to the second molar on left quadrant development was undertaken and DA was assessed using Willems method. Results and Discussion: The present study showed a significant correlation between DA and CA in both males (r = 0.71 and females (r = 0.88. The overall mean difference between the estimated DA and CA for males was 0.69 ± 2.14 years (P 0.05. Willems method underestimated the mean age of males by 0.69 years and females by 0.08 years and showed that females mature earlier than males in selected population. The mean difference between DA and CA according to Willems method was 0.39 years and is statistically significant (P < 0.05. Conclusion: This study showed significant relation between DA and CA. Thus, digital radiographic assessment of mandibular teeth development can be used to generate mean DA using Willems method and also the estimated age range for an individual of unknown CA.

  11. Remote ultrasound palpation for robotic interventions using absolute elastography.

    Science.gov (United States)

    Schneider, Caitlin; Baghani, Ali; Rohling, Robert; Salcudean, Septimiu

    2012-01-01

    Although robotic surgery has addressed many of the challenges presented by minimally invasive surgery, haptic feedback and the lack of knowledge of tissue stiffness is an unsolved problem. This paper presents a system for finding the absolute elastic properties of tissue using a freehand ultrasound scanning technique, which utilizes the da Vinci Surgical robot and a custom 2D ultrasound transducer for intraoperative use. An external exciter creates shear waves in the tissue, and a local frequency estimation method computes the shear modulus. Results are reported for both phantom and in vivo models. This system can be extended to any 6 degree-of-freedom tracking method and any 2D transducer to provide real-time absolute elastic properties of tissue.

  12. Estimating Age-Dependent Extinction: Contrasting Evidence from Fossils and Phylogenies.

    Science.gov (United States)

    Hagen, Oskar; Andermann, Tobias; Quental, Tiago B; Antonelli, Alexandre; Silvestro, Daniele

    2018-05-01

    The estimation of diversification rates is one of the most vividly debated topics in modern systematics, with considerable controversy surrounding the power of phylogenetic and fossil-based approaches in estimating extinction. Van Valen's seminal work from 1973 proposed the "Law of constant extinction," which states that the probability of extinction of taxa is not dependent on their age. This assumption of age-independent extinction has prevailed for decades with its assessment based on survivorship curves, which, however, do not directly account for the incompleteness of the fossil record, and have rarely been applied at the species level. Here, we present a Bayesian framework to estimate extinction rates from the fossil record accounting for age-dependent extinction (ADE). Our approach, unlike previous implementations, explicitly models unobserved species and accounts for the effects of fossil preservation on the observed longevity of sampled lineages. We assess the performance and robustness of our method through extensive simulations and apply it to a fossil data set of terrestrial Carnivora spanning the past 40 myr. We find strong evidence of ADE, as we detect the extinction rate to be highest in young species and declining with increasing species age. For comparison, we apply a recently developed analogous ADE model to a dated phylogeny of extant Carnivora. Although the phylogeny-based analysis also infers ADE, it indicates that the extinction rate, instead, increases with increasing taxon age. The estimated mean species longevity also differs substantially, with the fossil-based analyses estimating 2.0 myr, in contrast to 9.8 myr derived from the phylogeny-based inference. Scrutinizing these discrepancies, we find that both fossil and phylogeny-based ADE models are prone to high error rates when speciation and extinction rates increase or decrease through time. However, analyses of simulated and empirical data show that fossil-based inferences are more

  13. Absolute nuclear material assay

    Science.gov (United States)

    Prasad, Manoj K [Pleasanton, CA; Snyderman, Neal J [Berkeley, CA; Rowland, Mark S [Alamo, CA

    2010-07-13

    A method of absolute nuclear material assay of an unknown source comprising counting neutrons from the unknown source and providing an absolute nuclear material assay utilizing a model to optimally compare to the measured count distributions. In one embodiment, the step of providing an absolute nuclear material assay comprises utilizing a random sampling of analytically computed fission chain distributions to generate a continuous time-evolving sequence of event-counts by spreading the fission chain distribution in time.

  14. An absolute distance interferometer with two external cavity diode lasers

    International Nuclear Information System (INIS)

    Hartmann, L; Meiners-Hagen, K; Abou-Zeid, A

    2008-01-01

    An absolute interferometer for length measurements in the range of several metres has been developed. The use of two external cavity diode lasers allows the implementation of a two-step procedure which combines the length measurement with a variable synthetic wavelength and its interpolation with a fixed synthetic wavelength. This synthetic wavelength is obtained at ≈42 µm by a modulation-free stabilization of both lasers to Doppler-reduced rubidium absorption lines. A stable reference interferometer is used as length standard. Different contributions to the total measurement uncertainty are discussed. It is shown that the measurement uncertainty can considerably be reduced by correcting the influence of vibrations on the measurement result and by applying linear regression to the quadrature signals of the absolute interferometer and the reference interferometer. The comparison of the absolute interferometer with a counting interferometer for distances up to 2 m results in a linearity error of 0.4 µm in good agreement with an estimation of the measurement uncertainty

  15. Economic productivity by age and sex: 2007 estimates for the United States.

    Science.gov (United States)

    Grosse, Scott D; Krueger, Kurt V; Mvundura, Mercy

    2009-07-01

    Human capital estimates of labor productivity are often used to estimate the economic impact of diseases and injuries that cause incapacitation or death. Estimates of average hourly, annual, and lifetime economic productivity, both market and household, were calculated in 2007 US dollars for 5-year age groups for men, women, and both sexes in the United States. Data from the American Time Use Survey were used to estimate hours of paid work and household services and hourly and annual earnings and household productivity. Present values of discounted lifetime earnings were calculated for each age group using the 2004 US life tables and a discount rate of 3% per year and assuming future productivity growth of 1% per year. The estimates of hours and productivity were calculated using the time diaries of 72,922 persons included in the American Time Use Survey for the years 2003 to 2007. The present value of lifetime productivity is approximately $1.2 million in 2007 dollars for children under 5 years of age. For adults in their 20s and 30s, it is approximately $1.6 million and then it declines with increasing age. Productivity estimates are higher for males than for females, more for market productivity than for total productivity. Changes in hours of paid employment and household services can affect economic productivity by age and sex. This is the first publication to include estimates of household services based on contemporary time use data for the US population.

  16. Thermoluminescence and new 14C age estimates for late quaternary loesses in southwestern Nebraska

    Science.gov (United States)

    Maat, P.B.; Johnson, W.C.

    1996-01-01

    Loess of late Quaternary age mantles most of Nebraska south of the Platte River Valley. At least five late Quaternary loesses are recognized: from oldest to youngest, one or more undifferentiated pre-lllinoian loesses, the Loveland Loess, the Gilman Canyon Loess, which exhibits a well developed soil and rests unconformably on the Sangamon soil, the Peoria Loess capped by the Brady soil, and the Bignell Loess, which is distributed discontinuously. Previous research shows that the Loveland Loess is Illinoian. the Gilman Canyon Loess and Peoria Loess are Wisconsin, and the Bignell Loess is Holocene. We present here the first thermoluminescence (TL) age estimates and new C ages for these late Quaternary loesses at two key sections in southwestern Nebraska, the Eustis ash pit and the Bignell Hill road cut. TL age estimates from all samples collected from Eustis ash pit and Bignell Hill were internally consistent. TL and C age estimates from these two sections generally agree and support previous age determinations. The TL age estimate on Loveland Loess indicates deposition at 163 ka. TL and radiocarbon age estimates indicate that Oilman Canyon Loess, believed to be deposited during the Farmdale interstade, first began to accumulate at about 40 ka: the lower part of the Gilman Canyon Loess is 36 ka at Eustis and the middle of the unit is 30 ka at Bignell Hill. The lower and upper parts of the Peoria Loess give age estimates of 24 ka and 17 ka, respectively. TL age estimates for deposition of the Bignell Loess are 9 ka near the base, in agreement with radiocarbon age estimates, and 6 ka immediately below the modern soil, substantiating its Holocene age. Comparisons of TL age estimates with ??18O and insolation curves which show loess deposition during interglacial and interstadial as well as glacial periods, indicate that loess deposition on the Great Plains can occur under a variety of climatic conditions.

  17. Thermodynamics of negative absolute pressures

    International Nuclear Information System (INIS)

    Lukacs, B.; Martinas, K.

    1984-03-01

    The authors show that the possibility of negative absolute pressure can be incorporated into the axiomatic thermodynamics, analogously to the negative absolute temperature. There are examples for such systems (GUT, QCD) processing negative absolute pressure in such domains where it can be expected from thermodynamical considerations. (author)

  18. Artificial Neural Networks and Gene Expression Programing based age estimation using facial features

    Directory of Open Access Journals (Sweden)

    Baddrud Z. Laskar

    2015-10-01

    Full Text Available This work is about estimating human age automatically through analysis of facial images. It has got a lot of real-world applications. Due to prompt advances in the fields of machine vision, facial image processing, and computer graphics, automatic age estimation via faces in computer is one of the dominant topics these days. This is due to widespread real-world applications, in areas of biometrics, security, surveillance, control, forensic art, entertainment, online customer management and support, along with cosmetology. As it is difficult to estimate the exact age, this system is to estimate a certain range of ages. Four sets of classifications have been used to differentiate a person’s data into one of the different age groups. The uniqueness about this study is the usage of two technologies i.e., Artificial Neural Networks (ANN and Gene Expression Programing (GEP to estimate the age and then compare the results. New methodologies like Gene Expression Programing (GEP have been explored here and significant results were found. The dataset has been developed to provide more efficient results by superior preprocessing methods. This proposed approach has been developed, tested and trained using both the methods. A public data set was used to test the system, FG-NET. The quality of the proposed system for age estimation using facial features is shown by broad experiments on the available database of FG-NET.

  19. On the Absolute Age of the Globular Cluster M92

    Science.gov (United States)

    Di Cecco, A.; Becucci, R.; Bono, G.; Monelli, M.; Stetson, P. B.; Degl'Innocenti, S.; Prada Moroni, P. G.; Nonino, M.; Weiss, A.; Buonanno, R.; Calamida, A.; Caputo, F.; Corsi, C. E.; Ferraro, I.; Iannicola, G.; Pulone, L.; Romaniello, M.; Walker, A. R.

    2010-09-01

    We present precise and deep optical photometry of the globular M92. Data were collected in three different photometric systems: Sloan Digital Sky Survey (g‧, r‧, i‧, and z‧ MegaCam at CFHT), Johnson-Kron-Cousins (B, V, and I; various ground-based telescopes), and Advanced Camera for Surveys (ACS) Vegamag (F475W, F555W, and F814W; Hubble Space Telescope). Special attention was given to the photometric calibration, and the precision of the ground-based data is generally better than 0.01 mag. We computed a new set of α-enhanced evolutionary models accounting for the gravitational settling of heavy elements at fixed chemical composition ([α/Fe] = +0.3, [Fe/H] = -2.32 dex, and Y = 0.248). The isochrones—assuming the same true distance modulus (μ = 14.74 mag), the same reddening [E(B - V) = 0.025 ± 0.010 mag], and the same reddening law—account for the stellar distribution along the main sequence and the red giant branch in different color-magnitude diagrams (i‧, g‧ - i‧ i‧, and g‧ - r‧ i‧, g‧ - z‧ I, and B - I and F814W and F475W-F814W). The same outcome applies to the comparison between the predicted zero-age horizontal-branch (ZAHB) and the HB stars. We also found a cluster age of 11 ± 1.5 Gyr, in good agreement with previous estimates. The error budget accounts for uncertainties in the input physics and the photometry. To test the possible occurrence of CNO-enhanced stars, we also computed two sets of α- and CNO-enhanced (by a factor of 3) models, both at fixed total metallicity ([M/H] = -2.10 dex) and at fixed iron abundance. We found that the isochrones based on the former set give the same cluster age (11 ± 1.5 Gyr) as the canonical α-enhanced isochrones. The isochrones based on the latter set also give a similar cluster age (10 ± 1.5 Gyr). These findings support previous results concerning the weak sensitivity of cluster isochrones to CNO-enhanced chemical mixtures. This paper makes use of data obtained from the Isaac Newton

  20. Elevated estimated arterial age is associated with metabolic syndrome and low-grade inflammation

    DEFF Research Database (Denmark)

    Greve, Sara V; Blicher, Marie K; Kruger, Ruan

    2016-01-01

    BACKGROUND: Arterial age can be estimated from equations relating arterial stiffness to age and blood pressure in large cohorts. We investigated whether estimated arterial age (eAA) was elevated in patients with the metabolic syndrome and/or known cardiovascular disease (CVD), which factors were...... of metabolic syndrome, Systematic COronary Risk Evaluation, or Framingham risk score. From age, mean blood pressure, and cfPWV, eAA and estimated cfPWV (ePWV) were calculated. In 2006, the combined cardiovascular endpoint (CEP) of cardiovascular death, nonfatal myocardial infarction, nonfatal stroke...

  1. The ossification pattern in paediatric occipito-cervical spine: is it possible to estimate real age?

    International Nuclear Information System (INIS)

    Lee, H.J.; Kim, J.T.; Shin, M.H.; Choi, D.Y.; Park, Y.S.; Hong, J.T.

    2015-01-01

    Aim: To retrospectively analyse the synchondrosis from the occipital bone to the whole cervical spine and determine the feasibility and validity of age estimation using computed tomography (CT) images. Material and methods: A total of 231 cervical spine or neck CT images of young children (<7 years of age) were examined. Twelve ossification centres were assessed (occiput: n = 2; atlas: n = 2; axis, n = 6; whole sub-axial vertebra: n = 2), and the ossification process was graded as open (O, fully lucent), osseous bridging (B, partially ossified), and fusion (F, totally ossified). After the first analysis was completed, the resulting chronological chart was used to estimate the age of 10 new cases in order to confirm the usefulness of the chart. Results: Infancy was easily estimated using the sub-axial or C2 posterior ossification centres, while the posterior occipital regions provided good estimation of age between 1–2 years. The most difficult period for accurate age estimation was between 2–4 years. However, the C2 anterior (neurocentral ossification) and C1 posterior regions did yield information to help determine the age around 3 years. The anterior occipital region was useful for age estimation between 4–5 years, and the C1-anterior region was potentially useful to help decide among the other parameters. The test for age estimation (TAE) had a very high ICC score (0.973) among the three observers. Conclusion: Segmentalised analysis can enhance the ability to estimate real age, at least by the year. The analysis of the occipital bone made a strong contribution to the usefulness of the chorological chart. An organised chronological chart can provide readily available information for age estimation, and the primary application of the above data (TAE) demonstrated the validity of this approach. -- Highlights: •Subaxial or C2 posterior regions was useful for age estimation between 0–1 year. •Posterior occipital regions provided good estimation of

  2. Similarity estimators for irregular and age uncertain time series

    Science.gov (United States)

    Rehfeld, K.; Kurths, J.

    2013-09-01

    Paleoclimate time series are often irregularly sampled and age uncertain, which is an important technical challenge to overcome for successful reconstruction of past climate variability and dynamics. Visual comparison and interpolation-based linear correlation approaches have been used to infer dependencies from such proxy time series. While the first is subjective, not measurable and not suitable for the comparison of many datasets at a time, the latter introduces interpolation bias, and both face difficulties if the underlying dependencies are nonlinear. In this paper we investigate similarity estimators that could be suitable for the quantitative investigation of dependencies in irregular and age uncertain time series. We compare the Gaussian-kernel based cross correlation (gXCF, Rehfeld et al., 2011) and mutual information (gMI, Rehfeld et al., 2013) against their interpolation-based counterparts and the new event synchronization function (ESF). We test the efficiency of the methods in estimating coupling strength and coupling lag numerically, using ensembles of synthetic stalagmites with short, autocorrelated, linear and nonlinearly coupled proxy time series, and in the application to real stalagmite time series. In the linear test case coupling strength increases are identified consistently for all estimators, while in the nonlinear test case the correlation-based approaches fail. The lag at which the time series are coupled is identified correctly as the maximum of the similarity functions in around 60-55% (in the linear case) to 53-42% (for the nonlinear processes) of the cases when the dating of the synthetic stalagmite is perfectly precise. If the age uncertainty increases beyond 5% of the time series length, however, the true coupling lag is not identified more often than the others for which the similarity function was estimated. Age uncertainty contributes up to half of the uncertainty in the similarity estimation process. Time series irregularity

  3. Similarity estimators for irregular and age-uncertain time series

    Science.gov (United States)

    Rehfeld, K.; Kurths, J.

    2014-01-01

    Paleoclimate time series are often irregularly sampled and age uncertain, which is an important technical challenge to overcome for successful reconstruction of past climate variability and dynamics. Visual comparison and interpolation-based linear correlation approaches have been used to infer dependencies from such proxy time series. While the first is subjective, not measurable and not suitable for the comparison of many data sets at a time, the latter introduces interpolation bias, and both face difficulties if the underlying dependencies are nonlinear. In this paper we investigate similarity estimators that could be suitable for the quantitative investigation of dependencies in irregular and age-uncertain time series. We compare the Gaussian-kernel-based cross-correlation (gXCF, Rehfeld et al., 2011) and mutual information (gMI, Rehfeld et al., 2013) against their interpolation-based counterparts and the new event synchronization function (ESF). We test the efficiency of the methods in estimating coupling strength and coupling lag numerically, using ensembles of synthetic stalagmites with short, autocorrelated, linear and nonlinearly coupled proxy time series, and in the application to real stalagmite time series. In the linear test case, coupling strength increases are identified consistently for all estimators, while in the nonlinear test case the correlation-based approaches fail. The lag at which the time series are coupled is identified correctly as the maximum of the similarity functions in around 60-55% (in the linear case) to 53-42% (for the nonlinear processes) of the cases when the dating of the synthetic stalagmite is perfectly precise. If the age uncertainty increases beyond 5% of the time series length, however, the true coupling lag is not identified more often than the others for which the similarity function was estimated. Age uncertainty contributes up to half of the uncertainty in the similarity estimation process. Time series irregularity

  4. Hierarchical Bayesian analysis to incorporate age uncertainty in growth curve analysis and estimates of age from length: Florida manatee (Trichechus manatus) carcasses

    Science.gov (United States)

    Schwarz, L.K.; Runge, M.C.

    2009-01-01

    Age estimation of individuals is often an integral part of species management research, and a number of ageestimation techniques are commonly employed. Often, the error in these techniques is not quantified or accounted for in other analyses, particularly in growth curve models used to describe physiological responses to environment and human impacts. Also, noninvasive, quick, and inexpensive methods to estimate age are needed. This research aims to provide two Bayesian methods to (i) incorporate age uncertainty into an age-length Schnute growth model and (ii) produce a method from the growth model to estimate age from length. The methods are then employed for Florida manatee (Trichechus manatus) carcasses. After quantifying the uncertainty in the aging technique (counts of ear bone growth layers), we fit age-length data to the Schnute growth model separately by sex and season. Independent prior information about population age structure and the results of the Schnute model are then combined to estimate age from length. Results describing the age-length relationship agree with our understanding of manatee biology. The new methods allow us to estimate age, with quantified uncertainty, for 98% of collected carcasses: 36% from ear bones, 62% from length.

  5. Revised age estimates of the Euphrosyne family

    Science.gov (United States)

    Carruba, Valerio; Masiero, Joseph R.; Cibulková, Helena; Aljbaae, Safwan; Espinoza Huaman, Mariela

    2015-08-01

    The Euphrosyne family, a high inclination asteroid family in the outer main belt, is considered one of the most peculiar groups of asteroids. It is characterized by the steepest size frequency distribution (SFD) among families in the main belt, and it is the only family crossed near its center by the ν6 secular resonance. Previous studies have shown that the steep size frequency distribution may be the result of the dynamical evolution of the family.In this work we further explore the unique dynamical configuration of the Euphrosyne family by refining the previous age values, considering the effects of changes in shapes of the asteroids during YORP cycle (``stochastic YORP''), the long-term effect of close encounters of family members with (31) Euphrosyne itself, and the effect that changing key parameters of the Yarkovsky force (such as density and thermal conductivity) has on the estimate of the family age obtained using Monte Carlo methods. Numerical simulations accounting for the interaction with the local web of secular and mean-motion resonances allow us to refine previous estimates of the family age. The cratering event that formed the Euphrosyne family most likely occurred between 560 and 1160 Myr ago, and no earlier than 1400 Myr ago when we allow for larger uncertainties in the key parameters of the Yarkovsky force.

  6. Evaluation of the Applicability of Different Age Determination Methods for Estimating Age of the Endangered African Wild Dog (Lycaon Pictus.

    Directory of Open Access Journals (Sweden)

    Moreangels M Mbizah

    Full Text Available African wild dogs (Lycaon pictus are endangered and their population continues to decline throughout their range. Given their conservation status, more research focused on their population dynamics, population growth and age specific mortality is needed and this requires reliable estimates of age and age of mortality. Various age determination methods from teeth and skull measurements have been applied in numerous studies and it is fundamental to test the validity of these methods and their applicability to different species. In this study we assessed the accuracy of estimating chronological age and age class of African wild dogs, from dental age measured by (i counting cementum annuli (ii pulp cavity/tooth width ratio, (iii tooth wear (measured by tooth crown height (iv tooth wear (measured by tooth crown width/crown height ratio (v tooth weight and (vi skull measurements (length, width and height. A sample of 29 African wild dog skulls, from opportunistically located carcasses was analysed. Linear and ordinal regression analysis was done to investigate the performance of each of the six age determination methods in predicting wild dog chronological age and age class. Counting cementum annuli was the most accurate method for estimating chronological age of wild dogs with a 79% predictive capacity, while pulp cavity/tooth width ratio was also a reliable method with a 68% predictive capacity. Counting cementum annuli and pulp cavity/tooth width ratio were again the most accurate methods for separating wild dogs into three age classes (6-24 months; 25-60 months and > 60 months, with a McFadden's Pseudo-R2 of 0.705 and 0.412 respectively. The use of the cementum annuli method is recommended when estimating age of wild dogs since it is the most reliable method. However, its use is limited as it requires tooth extraction and shipping, is time consuming and expensive, and is not applicable to living individuals. Pulp cavity/tooth width ratio is a

  7. The comparison of absolute dating (Radiocarbon dating) and relative dating of Pringapus and Gondosuli temples

    International Nuclear Information System (INIS)

    Faisal, W; Arumbinang, H; Taftazani, A; Widayati, S; Sumiyatno; Suhardi

    1996-01-01

    The absolute dating (radiocarbon, 14 C dating) and relative dating of Pringapus and Gondosuli temples in Temanggung regency (district) of Central Java Province have been carried out. The field sampling was done especially with the purpose to obtain vertical data, so that excavation method was adopted in the case. The main data were the ecofacts of organic habitation such as bones, woods, charcoals, shells, and paper artefacts. The artefacts data were used as a comparison. The comparative data analysis were conducted at Yogyakarta archaeological Department Laboratory, thus included dating of artefacts which were performed according to archaeological analysis procedures, generally based on the attributes attached to the artefacts, whereas the absolute dating of charcoal samples were performed in the Radiocarbon Dating Laboratory at Yogyakarta Nuclear Research Centre. Based on the relative dating of epigraphy content on the andesit rock from Gondosuli Temple which showed the year of 754 Saka or 832 AD, the Pringapus Temple was estimated to be built in the 850 AD. According to the absolute dating (Radiocarbon Dating with delta 13 C and tree ring corrections) the age for Gondosuli temple based on GDS/LU-2/Spit-7 samples is (384 -602) AD and from GDS/LU-2/Spit-8 = (452 - 652) AD. With these significant differences in the results obtained, it can be concluded that culture environment where the sample were collected already existed before the temple was built. Further investigation is still required

  8. Communication: The absolute shielding scales of oxygen and sulfur revisited

    Energy Technology Data Exchange (ETDEWEB)

    Komorovsky, Stanislav; Repisky, Michal; Malkin, Elena; Ruud, Kenneth, E-mail: kenneth.ruud@uit.no [Centre for Theoretical and Computational Chemistry, University of Tromsø — The Arctic University of Norway, N-9037 Tromsø (Norway); Gauss, Jürgen [Institut für Physikalische Chemie, Johannes Gutenberg-Universität Mainz, Duesbergweg 10-14, D-55128 Mainz (Germany)

    2015-03-07

    We present an updated semi-experimental absolute shielding scale for the {sup 17}O and {sup 33}S nuclei. These new shielding scales are based on accurate rotational microwave data for the spin–rotation constants of H{sub 2}{sup 17}O [Puzzarini et al., J. Chem. Phys. 131, 234304 (2009)], C{sup 17}O [Cazzoli et al., Phys. Chem. Chem. Phys. 4, 3575 (2002)], and H{sub 2}{sup 33}S [Helgaker et al., J. Chem. Phys. 139, 244308 (2013)] corrected both for vibrational and temperature effects estimated at the CCSD(T) level of theory as well as for the relativistic corrections to the relation between the spin–rotation constant and the absolute shielding constant. Our best estimate for the oxygen shielding constants of H{sub 2}{sup 17}O is 328.4(3) ppm and for C{sup 17}O −59.05(59) ppm. The relativistic correction for the sulfur shielding of H{sub 2}{sup 33}S amounts to 3.3%, and the new sulfur shielding constant for this molecule is 742.9(4.6) ppm.

  9. Cerebral Blood Flow and A beta-Amyloid Estimates by WARM Analysis of [C-11]PiB Uptake Distinguish among and between Neurodegenerative Disorders and Aging

    DEFF Research Database (Denmark)

    Rodell, Anders B.; O'Keefe, Graeme; Rowe, Christopher C.

    2017-01-01

    groups as a whole, sCBF estimates revealed the greatest discrimination between the patient and HC groups. WARM resolves a major issue of amyloid load quantification with [11C]PiB in human brain by determining absolute sCBF and amyloid load measures from the same images. The two parameter approach......Background: We report results of the novel Washout Allometric Reference Method (WARM) that uses estimates of cerebral blood flow and amyloid load from the same [11C]Pittsburgh Compound B ([11C]PiB) retention maps in brain to distinguish between patients with different forms dementia, including...... with Lewy bodies (DLB), five patients with frontotemporal lobar degeneration (FTLD), five patients with mild cognitive impairment, and 29 age-matched healthy control subjects (HC)], underwent analysis of PiB delivery and retention by means of WARM for quantitation of [11C]PiB's binding potentials (BPND...

  10. Probabilistic graphical models to deal with age estimation of living persons.

    Science.gov (United States)

    Sironi, Emanuele; Gallidabino, Matteo; Weyermann, Céline; Taroni, Franco

    2016-03-01

    Due to the rise of criminal, civil and administrative judicial situations involving people lacking valid identity documents, age estimation of living persons has become an important operational procedure for numerous forensic and medicolegal services worldwide. The chronological age of a given person is generally estimated from the observed degree of maturity of some selected physical attributes by means of statistical methods. However, their application in the forensic framework suffers from some conceptual and practical drawbacks, as recently claimed in the specialised literature. The aim of this paper is therefore to offer an alternative solution for overcoming these limits, by reiterating the utility of a probabilistic Bayesian approach for age estimation. This approach allows one to deal in a transparent way with the uncertainty surrounding the age estimation process and to produce all the relevant information in the form of posterior probability distribution about the chronological age of the person under investigation. Furthermore, this probability distribution can also be used for evaluating in a coherent way the possibility that the examined individual is younger or older than a given legal age threshold having a particular legal interest. The main novelty introduced by this work is the development of a probabilistic graphical model, i.e. a Bayesian network, for dealing with the problem at hand. The use of this kind of probabilistic tool can significantly facilitate the application of the proposed methodology: examples are presented based on data related to the ossification status of the medial clavicular epiphysis. The reliability and the advantages of this probabilistic tool are presented and discussed.

  11. Secondary Forest Age and Tropical Forest Biomass Estimation Using TM

    Science.gov (United States)

    Nelson, R. F.; Kimes, D. S.; Salas, W. A.; Routhier, M.

    1999-01-01

    The age of secondary forests in the Amazon will become more critical with respect to the estimation of biomass and carbon budgets as tropical forest conversion continues. Multitemporal Thematic Mapper data were used to develop land cover histories for a 33,000 Square kM area near Ariquemes, Rondonia over a 7 year period from 1989-1995. The age of the secondary forest, a surrogate for the amount of biomass (or carbon) stored above-ground, was found to be unimportant in terms of biomass budget error rates in a forested TM scene which had undergone a 20% conversion to nonforest/agricultural cover types. In such a situation, the 80% of the scene still covered by primary forest accounted for over 98% of the scene biomass. The difference between secondary forest biomass estimates developed with and without age information were inconsequential relative to the estimate of biomass for the entire scene. However, in futuristic scenarios where all of the primary forest has been converted to agriculture and secondary forest (55% and 42% respectively), the ability to age secondary forest becomes critical. Depending on biomass accumulation rate assumptions, scene biomass budget errors on the order of -10% to +30% are likely if the age of the secondary forests are not taken into account. Single-date TM imagery cannot be used to accurately age secondary forests into single-year classes. A neural network utilizing TM band 2 and three TM spectral-texture measures (bands 3 and 5) predicted secondary forest age over a range of 0-7 years with an RMSE of 1.59 years and an R(Squared) (sub actual vs predicted) = 0.37. A proposal is made, based on a literature review, to use satellite imagery to identify general secondary forest age groups which, within group, exhibit relatively constant biomass accumulation rates.

  12. Radiocarbon ages of pedogenic calcic nodules formed within vertisols, Coimbatore region, Tamil Nadu, India

    International Nuclear Information System (INIS)

    Achyuthan, H.; Flora, O.; Braida, M.; Stenni, B.; Shankar, N.

    2009-05-01

    In this paper we discuss the limitation of radiocarbon dates on the pedogenic calcic nodules formed in situ within the vertisols in the upland region of Coimbatore, Tamil Nadu. The radiocarbon ages were obtained using low level scintillation counters and the ages range from ∼24 Ka to ∼31 Ka. The ages correlate well with the marine isotope stage of Late MIS3. Since the calcic nodules are pedogenised and formed in a terrestrial open system we express caution in the interpretation of the radiocarbon ages obtained on pedogenic carbonate nodules. The radiocarbon dates represent maximum ages and hence the ages measured should only be considered as age estimates and not absolute geologic ages. Multiple sub-mm size subsamples could provide more reliable estimates of soil chronology. (author)

  13. Estimation of sex and age of ''virtual skeletons''-a feasibility study

    International Nuclear Information System (INIS)

    Grabherr, Silke; Cooper, Christine; Ulrich-Bochsler, Susi; Uldin, Tanya; Ross, Steffen; Oesterhelweg, Lars; Bolliger, Stephan; Thali, Michael J.; Christe, Andreas; Schnyder, Pierre; Mangin, Patrice

    2009-01-01

    This article presents a feasibility study with the objective of investigating the potential of multi-detector computed tomography (MDCT) to estimate the bone age and sex of deceased persons. To obtain virtual skeletons, the bodies of 22 deceased persons with known age at death were scanned by MDCT using a special protocol that consisted of high-resolution imaging of the skull, shoulder girdle (including the upper half of the humeri), the symphysis pubis and the upper halves of the femora. Bone and soft-tissue reconstructions were performed in two and three dimensions. The resulting data were investigated by three anthropologists with different professional experience. Sex was determined by investigating three-dimensional models of the skull and pelvis. As a basic orientation for the age estimation, the complex method according to Nemeskeri and co-workers was applied. The final estimation was effected using additional parameters like the state of dentition, degeneration of the spine, etc., which where chosen individually by the three observers according to their experience. The results of the study show that the estimation of sex and age is possible by the use of MDCT. Virtual skeletons present an ideal collection for anthropological studies, because they are obtained in a non-invasive way and can be investigated ad infinitum. (orig.)

  14. Human podocyte depletion in association with older age and hypertension.

    Science.gov (United States)

    Puelles, Victor G; Cullen-McEwen, Luise A; Taylor, Georgina E; Li, Jinhua; Hughson, Michael D; Kerr, Peter G; Hoy, Wendy E; Bertram, John F

    2016-04-01

    Podocyte depletion plays a major role in the development and progression of glomerulosclerosis. Many kidney diseases are more common in older age and often coexist with hypertension. We hypothesized that podocyte depletion develops in association with older age and is exacerbated by hypertension. Kidneys from 19 adult Caucasian American males without overt renal disease were collected at autopsy in Mississippi. Demographic data were obtained from medical and autopsy records. Subjects were categorized by age and hypertension as potential independent and additive contributors to podocyte depletion. Design-based stereology was used to estimate individual glomerular volume and total podocyte number per glomerulus, which allowed the calculation of podocyte density (number per volume). Podocyte depletion was defined as a reduction in podocyte number (absolute depletion) or podocyte density (relative depletion). The cortical location of glomeruli (outer or inner cortex) and presence of parietal podocytes were also recorded. Older age was an independent contributor to both absolute and relative podocyte depletion, featuring glomerular hypertrophy, podocyte loss, and thus reduced podocyte density. Hypertension was an independent contributor to relative podocyte depletion by exacerbating glomerular hypertrophy, mostly in glomeruli from the inner cortex. However, hypertension was not associated with podocyte loss. Absolute and relative podocyte depletion were exacerbated by the combination of older age and hypertension. The proportion of glomeruli with parietal podocytes increased with age but not with hypertension alone. These findings demonstrate that older age and hypertension are independent and additive contributors to podocyte depletion in white American men without kidney disease. Copyright © 2016 the American Physiological Society.

  15. Age estimates and stick-nest rat middens

    International Nuclear Information System (INIS)

    Pearson, S.; Lawson, E.

    1998-01-01

    A total of 112 radiocarbon analyses on stick-nest rat middens gathered from published and grey literature show (see figure) that the middens of stick-nest rats have a positively skewed distribution. The average of all the estimates is ca. 2967 BP with the oldest midden dated at around 10870 BP. Over 75% of the results are younger than -4480 BP. Possible explanations for this pattern include; sample bias, rate of midden and cave decay, a real pattern of midden age distribution and development of techniques. The components of the midden being used for radiocarbon analysis has been remarkably uniform. This reflects the small number of researchers in the field and the experience of the American packrat midden research. Early researchers using conventional methods used charcoal and large mixtures of material whereas AMS now allows individual scats to be analysed. In fact 37% of analyses have been on scats as these provide direct evidence of midden occupation and are plentiful in the midden matrix. 66% of analyses used AINSE's AMS method and 23% used conventional methods - the distribution of results using the two methods are similar. A number of dates have incomplete laboratory or methods information. Similar analysis of packrat midden dates in the United States identified both ecological and systematic bias in the age patterns (Webb 1986). The efficacy of midden analysis in Australia, as in America, is limited by the cost of age estimates

  16. Strategic Decision-Making Learning from Label Distributions: An Approach for Facial Age Estimation.

    Science.gov (United States)

    Zhao, Wei; Wang, Han

    2016-06-28

    Nowadays, label distribution learning is among the state-of-the-art methodologies in facial age estimation. It takes the age of each facial image instance as a label distribution with a series of age labels rather than the single chronological age label that is commonly used. However, this methodology is deficient in its simple decision-making criterion: the final predicted age is only selected at the one with maximum description degree. In many cases, different age labels may have very similar description degrees. Consequently, blindly deciding the estimated age by virtue of the highest description degree would miss or neglect other valuable age labels that may contribute a lot to the final predicted age. In this paper, we propose a strategic decision-making label distribution learning algorithm (SDM-LDL) with a series of strategies specialized for different types of age label distribution. Experimental results from the most popular aging face database, FG-NET, show the superiority and validity of all the proposed strategic decision-making learning algorithms over the existing label distribution learning and other single-label learning algorithms for facial age estimation. The inner properties of SDM-LDL are further explored with more advantages.

  17. A radiographic study estimating age of mandibular third molars by periodontal ligament visibility.

    Science.gov (United States)

    Chaudhary, M A; Liversidge, H M

    2017-12-01

    Visibility of the periodontal ligament of mandibular third molars (M3) has been suggested as a method to estimate age. To assess the accuracy of this method and compare the visibility of the periodontal ligament in the left M3 with the right M3. The sample was archived panoramic dental radiographs of 163 individuals (75 males, 88 females, age 16-53 years) with mature M3's. Reliability was assessed using Kappa. Accuracy was assessed by subtracting chronological age from estimated age for males and females. Stages were cross-tabulated against age stages younger than and at least 18 and 21 years of age. Stages were compared in the left M3 and right M3. Analysis showed excellent intra-observer reliability. Mean difference between estimated and chronological ages was 7.21 years (SD 5.16) for left M3 and 7.69 (SD 6.08) for right M3 in males and 6.87 (SD 5.83) for left M3 and 8.61 (SD 6.58) for right M3 in females. Minimum ages of stages 0 to 2 were younger than previously reported, despite a small sample of individuals younger than 18. The left and right M3 stage differed in 46% of the 85 individuals with readings from both side and estimated age differed from -10.5 to 12.2 years between left and right. Accuracy of this method was between 6 and 8 years with an error of 5 to 6 years. The number of individuals with mature M3 apices younger than 18 years was small. The stage of visibility of the periodontal ligament differed between left and right in almost half of our sample with both teeth present. Our findings question the use of this method to estimate age or to discriminate between age younger and at least 18 years.

  18. Hybrid method for consistent model of the Pacific absolute plate motion and a test for inter-hotspot motion since 70Ma

    Science.gov (United States)

    Harada, Y.; Wessel, P.; Sterling, A.; Kroenke, L.

    2002-12-01

    Inter-hotspot motion within the Pacific plate is one of the most controversial issues in recent geophysical studies. However, it is a fact that many geophysical and geological data including ages and positions of seamount chains in the Pacific plate can largely be explained by a simple model of absolute motion derived from assumptions of rigid plates and fixed hotspots. Therefore we take the stand that if a model of plate motion can explain the ages and positions of Pacific hotspot tracks, inter-hotspot motion would not be justified. On the other hand, if any discrepancies between the model and observations are found, the inter-hotspot motion may then be estimated from these discrepancies. To make an accurate model of the absolute motion of the Pacific plate, we combined two different approaches: the polygonal finite rotation method (PFRM) by Harada and Hamano (2000) and the hot-spotting technique developed by Wessel and Kroenke (1997). The PFRM can determine accurate positions of finite rotation poles for the Pacific plate if the present positions of hotspots are known. On the other hand, the hot-spotting technique can predict present positions of hotspots if the absolute plate motion is given. Therefore we can undertake iterative calculations using the two methods. This hybrid method enables us to determine accurate finite rotation poles for the Pacific plate solely from geometry of Hawaii, Louisville and Easter(Crough)-Line hotspot tracks from around 70 Ma to present. Information of ages can be independently assigned to the model after the poles and rotation angles are determined. We did not detect any inter-hotspot motion from the geometry of these Pacific hotspot tracks using this method. The Ar-Ar ages of Pacific seamounts including new age data of ODP Leg 197 are used to test the newly determined model of the Pacific plate motion. The ages of Hawaii, Louisville, Easter(Crough)-Line, and Cobb hotspot tracks are quite consistent with each other from 70 Ma to

  19. Demirjian approach of dental age estimation: Abridged for operator ease.

    Science.gov (United States)

    Jain, Vanshika; Kapoor, Priyanka; Miglani, Ragini

    2016-01-01

    Present times have seen an alarming increase in incidence of crimes by juveniles and of mass destruction that Highlight the preponderance of individual age estimation. Of the numerous techniques employed for age assessment, dental age estimation (DAE) and its correlation with chronological age (CA) have been of great significance in the recent past. Demirjian system, considered as gold standard in DAE is a simple and convenient method for DAE, though,, although, referring to multiple tables make it cumbersome and less eco friendly due to excessive paper load. The present study was aimed to develop a comprehensive chart (DAEcc) inclusive of all Demirjian tables and developmental stages of teeth and also to as well as to test the operator ease of 50 undergraduate dental students in performing DAE using this chart. The study was performed in two stages, wherein the first stage was aimed at formulation of the comprehensive chart (DAE CC ) which included pictorial representation of calcification stages, the Federation Dentaire Internationale notation of the teeth, and the corresponding scores for each stage with a concluding column at the end to enter the total score. The second stage assessed the applicability of the ease of DAE by DAE CC , whereby fifty 2 nd year BDS students were asked to trace the calcification stages of the seven permanent left mandibular teeth on a panorex, identify the correct stage, assign the corresponding score, and to calculate the total score for subsequent dental age assessment. showed that average time taken by the students for tracing seven mandibular teeth was 5 min and for assessment of dental age was 7 min. The total time taken for DAE was approximately 12 min, thus making the procedure less time consuming. Hence, this study proposes the use of DAEcc for age estimation due to ease in comprehension and execution of Demirjian system.

  20. Human age estimation framework using different facial parts

    Directory of Open Access Journals (Sweden)

    Mohamed Y. El Dib

    2011-03-01

    Full Text Available Human age estimation from facial images has a wide range of real-world applications in human computer interaction (HCI. In this paper, we use the bio-inspired features (BIF to analyze different facial parts: (a eye wrinkles, (b whole internal face (without forehead area and (c whole face (with forehead area using different feature shape points. The analysis shows that eye wrinkles which cover 30% of the facial area contain the most important aging features compared to internal face and whole face. Furthermore, more extensive experiments are made on FG-NET database by increasing the number of missing pictures in older age groups using MORPH database to enhance the results.

  1. An age estimation method using brain local features for T1-weighted images.

    Science.gov (United States)

    Kondo, Chihiro; Ito, Koichi; Kai Wu; Sato, Kazunori; Taki, Yasuyuki; Fukuda, Hiroshi; Aoki, Takafumi

    2015-08-01

    Previous statistical analysis studies using large-scale brain magnetic resonance (MR) image databases have examined that brain tissues have age-related morphological changes. This fact indicates that one can estimate the age of a subject from his/her brain MR image by evaluating morphological changes with healthy aging. This paper proposes an age estimation method using local features extracted from T1-weighted MR images. The brain local features are defined by volumes of brain tissues parcellated into local regions defined by the automated anatomical labeling atlas. The proposed method selects optimal local regions to improve the performance of age estimation. We evaluate performance of the proposed method using 1,146 T1-weighted images from a Japanese MR image database. We also discuss the medical implication of selected optimal local regions.

  2. Estimating brain age using high-resolution pattern recognition: Younger brains in long-term meditation practitioners.

    Science.gov (United States)

    Luders, Eileen; Cherbuin, Nicolas; Gaser, Christian

    2016-07-01

    Normal aging is known to be accompanied by loss of brain substance. The present study was designed to examine whether the practice of meditation is associated with a reduced brain age. Specific focus was directed at age fifty and beyond, as mid-life is a time when aging processes are known to become more prominent. We applied a recently developed machine learning algorithm trained to identify anatomical correlates of age in the brain translating those into one single score: the BrainAGE index (in years). Using this validated approach based on high-dimensional pattern recognition, we re-analyzed a large sample of 50 long-term meditators and 50 control subjects estimating and comparing their brain ages. We observed that, at age fifty, brains of meditators were estimated to be 7.5years younger than those of controls. In addition, we examined if the brain age estimates change with increasing age. While brain age estimates varied only little in controls, significant changes were detected in meditators: for every additional year over fifty, meditators' brains were estimated to be an additional 1month and 22days younger than their chronological age. Altogether, these findings seem to suggest that meditation is beneficial for brain preservation, effectively protecting against age-related atrophy with a consistently slower rate of brain aging throughout life. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. A novel approach for absolute radar calibration: formulation and theoretical validation

    Directory of Open Access Journals (Sweden)

    C. Merker

    2015-06-01

    Full Text Available The theoretical framework of a novel approach for absolute radar calibration is presented and its potential analysed by means of synthetic data to lay out a solid basis for future practical application. The method presents the advantage of an absolute calibration with respect to the directly measured reflectivity, without needing a previously calibrated reference device. It requires a setup comprising three radars: two devices oriented towards each other, measuring reflectivity along the same horizontal beam and operating within a strongly attenuated frequency range (e.g. K or X band, and one vertical reflectivity and drop size distribution (DSD profiler below this connecting line, which is to be calibrated. The absolute determination of the calibration factor is based on attenuation estimates. Using synthetic, smooth and geometrically idealised data, calibration is found to perform best using homogeneous precipitation events with rain rates high enough to ensure a distinct attenuation signal (reflectivity above ca. 30 dBZ. Furthermore, the choice of the interval width (in measuring range gates around the vertically pointing radar, needed for attenuation estimation, is found to have an impact on the calibration results. Further analysis is done by means of synthetic data with realistic, inhomogeneous precipitation fields taken from measurements. A calibration factor is calculated for each considered case using the presented method. Based on the distribution of the calculated calibration factors, the most probable value is determined by estimating the mode of a fitted shifted logarithmic normal distribution function. After filtering the data set with respect to rain rate and inhomogeneity and choosing an appropriate length of the considered attenuation path, the estimated uncertainty of the calibration factor is of the order of 1 to 11 %, depending on the chosen interval width. Considering stability and accuracy of the method, an interval of

  4. Do the age differences given by relative or absolute chronologies of the most ancient meteorites correspond to real age differences

    International Nuclear Information System (INIS)

    Pellas, P.

    1982-01-01

    Recent results from absolute and relative chronologies of the most ancient meteorites are reviewed in order to analyze if they are significant or not. Use of the various chronometers to analyze the same meteoritic sample is shown to be an interesting approach to retrace the prehistory of meteorites and their environments. (orig.)

  5. Raman Microspectrometry: An Alternative Method of Age Estimation from Dentin and Cementum

    Directory of Open Access Journals (Sweden)

    Karuna Kumari

    2017-10-01

    Full Text Available Introduction: Raman spectroscopy is simple, quick, sensitive and non destructive form of tissue examination that provides vital data about the structure, molecular composition and interactions within a sample. The human hard tissues like teeth and bone are able to resist decay for long even after other tissues are lost, thus have valuable forensic importance. Aim: To ascertain the known age of the teeth by analysing dentin and cementum using Raman microspectrometry and assess the accuracy of age estimation by comparison of dentin with cementum. Materials and Methods: The sound permanent extracted tooth specimens (40 of age ranging between 12-74 years were collected and sectioned longitudinally and different dentinal and cemental areas were analysed by Raman microspectrometry. The spectra of dentin and cementum were used as predictors of age estimation. For each sample, ratios were obtained for dentin and cementum areas, and Pearson’s correlation coefficient was calculated. Ratios, which had a correlation coefficient greater than 0.40 were used for further statistical analysis. This led to selection of ratios only for dentin areas, and it allowed us to develop a regression formula. Partial Least Square (PLS regression method was used for computing our model. Results: A significant correlation was observed between the actual chronological age and predicted age of the individual using dentinal areas of the tooth. A closest to the estimated result was achieved, with an error of three years between predicted and actual chorological age. Conclusion: Raman microspectrometry may be considered as an alternative to the conventional method of age estimation and contribute to the identification of individuals.

  6. Improvement of age estimation using amino acid racemization in a case of pink teeth.

    Science.gov (United States)

    Ohtani, S; Yamada, Y; Yamamoto, I

    1998-03-01

    Age was estimated from pink teeth using racemization of dentinal aspartic acid. Materials for identification were two lower second premolars. The body was determined to be that of a 40-year-old man; however, the age of the decedent had been estimated to be 29 and 30 years by the conventional method and 30 years from findings in the oral cavity. To clarify the cause of this difference, the powdered teeth were further washed in 0.01 mol/L hydrochloric acid. The racemization ratio (D/L ratio) of ordinary white teeth from persons of known age was slightly lower than that before washing, whereas that of the teeth used for identification was higher than before washing. The calculated age of the decedent using the racemization ratio of his teeth was between 36 and 37 years. These results suggest that age estimated from pink teeth is probably underestimated, but a more accurate age estimate can be obtained after adequate washing.

  7. The Berg Balance Scale has high intra- and inter-rater reliability but absolute reliability varies across the scale: a systematic review.

    Science.gov (United States)

    Downs, Stephen; Marquez, Jodie; Chiarelli, Pauline

    2013-06-01

    What is the intra-rater and inter-rater relative reliability of the Berg Balance Scale? What is the absolute reliability of the Berg Balance Scale? Does the absolute reliability of the Berg Balance Scale vary across the scale? Systematic review with meta-analysis of reliability studies. Any clinical population that has undergone assessment with the Berg Balance Scale. Relative intra-rater reliability, relative inter-rater reliability, and absolute reliability. Eleven studies involving 668 participants were included in the review. The relative intrarater reliability of the Berg Balance Scale was high, with a pooled estimate of 0.98 (95% CI 0.97 to 0.99). Relative inter-rater reliability was also high, with a pooled estimate of 0.97 (95% CI 0.96 to 0.98). A ceiling effect of the Berg Balance Scale was evident for some participants. In the analysis of absolute reliability, all of the relevant studies had an average score of 20 or above on the 0 to 56 point Berg Balance Scale. The absolute reliability across this part of the scale, as measured by the minimal detectable change with 95% confidence, varied between 2.8 points and 6.6 points. The Berg Balance Scale has a higher absolute reliability when close to 56 points due to the ceiling effect. We identified no data that estimated the absolute reliability of the Berg Balance Scale among participants with a mean score below 20 out of 56. The Berg Balance Scale has acceptable reliability, although it might not detect modest, clinically important changes in balance in individual subjects. The review was only able to comment on the absolute reliability of the Berg Balance Scale among people with moderately poor to normal balance. Copyright © 2013 Australian Physiotherapy Association. Published by .. All rights reserved.

  8. Absolute efficiency calibration of HPGe detector by simulation method

    International Nuclear Information System (INIS)

    Narayani, K.; Pant, Amar D.; Verma, Amit K.; Bhosale, N.A.; Anilkumar, S.

    2018-01-01

    High resolution gamma ray spectrometry by HPGe detectors is a powerful radio analytical technique for estimation of activity of various radionuclides. In the present work absolute efficiency calibration of the HPGe detector was carried out using Monte Carlo simulation technique and results are compared with those obtained by experiment using standard radionuclides of 152 Eu and 133 Ba. The coincidence summing correction factors for the measurement of these nuclides were also calculated

  9. Relative estimation of the mineral ages using uranium migration

    International Nuclear Information System (INIS)

    Danis, A.

    1990-01-01

    Using the uranium fission track micro mapping technique the correlation between the age and uranium migration from inclusions was studied. It is shown that during geological time, as function of the mineral, its age and its uranium migration speed, the pattern of the track, clusters corresponding to the uranium inclusions got a typical feature. Thus for a bulk polished geological sample it is possible to establish an age succession of the constituent minerals as a function of the track cluster patterns. Also, it is shown that knowing the migration speed of the uranium in a mineral it is possible to estimate the age of this mineral by measuring the migration distance on the micro mapping. (Author)

  10. Precision of four otolith techniques for estimating age of white perch from a thermally altered reservoir

    Science.gov (United States)

    Snow, Richard A.; Porta, Michael J.; Long, James M.

    2018-01-01

    The White Perch Morone americana is an invasive species in many Midwestern states and is widely distributed in reservoir systems, yet little is known about the species' age structure and population dynamics. White Perch were first observed in Sooner Reservoir, a thermally altered cooling reservoir in Oklahoma, by the Oklahoma Department of Wildlife Conservation in 2006. It is unknown how thermally altered systems like Sooner Reservoir may affect the precision of White Perch age estimates. Previous studies have found that age structures from Largemouth Bass Micropterus salmoides and Bluegills Lepomis macrochirus from thermally altered reservoirs had false annuli, which increased error when estimating ages. Our objective was to quantify the precision of White Perch age estimates using four sagittal otolith preparation techniques (whole, broken, browned, and stained). Because Sooner Reservoir is thermally altered, we also wanted to identify the best month to collect a White Perch age sample based on aging precision. Ages of 569 White Perch (20–308 mm TL) were estimated using the four techniques. Age estimates from broken, stained, and browned otoliths ranged from 0 to 8 years; whole‐view otolith age estimates ranged from 0 to 7 years. The lowest mean coefficient of variation (CV) was obtained using broken otoliths, whereas the highest CV was observed using browned otoliths. July was the most precise month (lowest mean CV) for estimating age of White Perch, whereas April was the least precise month (highest mean CV). These results underscore the importance of knowing the best method to prepare otoliths for achieving the most precise age estimates and the best time of year to obtain those samples, as these factors may affect other estimates of population dynamics.

  11. Setting the light conditions for measuring root transparency for age-at-death estimation methods.

    Science.gov (United States)

    Adserias-Garriga, Joe; Nogué-Navarro, Laia; Zapico, Sara C; Ubelaker, Douglas H

    2018-03-01

    Age-at-death estimation is one of the main goals in forensic identification, being an essential parameter to determine the biological profile, narrowing the possibility of identification in cases involving missing persons and unidentified bodies. The study of dental tissues has been long considered as a proper tool for age estimation with several age estimation methods based on them. Dental age estimation methods can be divided into three categories: tooth formation and development, post-formation changes, and histological changes. While tooth formation and growth changes are important for fetal and infant consideration, when the end of dental and skeletal growth is achieved, post-formation or biochemical changes can be applied. Lamendin et al. in J Forensic Sci 37:1373-1379, (1992) developed an adult age estimation method based on root transparency and periodontal recession. The regression formula demonstrated its accuracy of use for 40 to 70-year-old individuals. Later on, Prince and Ubelaker in J Forensic Sci 47(1):107-116, (2002) evaluated the effects of ancestry and sex and incorporated root height into the equation, developing four new regression formulas for males and females of African and European ancestry. Even though root transparency is a key element in the method, the conditions for measuring this element have not been established. The aim of the present study is to set the light conditions measured in lumens that offer greater accuracy when applying the Lamendin et al. method modified by Prince and Ubelaker. The results must be also taken into account in the application of other age estimation methodologies using root transparency to estimate age-at-death.

  12. Defining and Estimating Healthy Aging in Spain: A Cross-sectional Study.

    Science.gov (United States)

    Rodriguez-Laso, Angel; McLaughlin, Sara J; Urdaneta, Elena; Yanguas, Javier

    2018-03-19

    Using an operational continuum of healthy aging developed by U.S. researchers, we sought to estimate the prevalence of healthy aging among older Spaniards, inform the development of a definition of healthy aging in Spain, and foster cross-national research on healthy aging. The ELES pilot study is a nationwide, cross-sectional survey of community-dwelling Spaniards 50 years and older. The prevalence of healthy aging was calculated for the 65 and over population using varying definitions. To evaluate their validity, we examined the association of healthy aging with the 8 foot up & go test, quality of life scores and self-perceived health using multiple linear and logistic regression. The estimated prevalence of healthy aging varied across the operational continuum, from 4.5% to 49.2%. Prevalence figures were greater for men and those aged 65 to 79 years and were higher than in the United States. Predicted mean physical performance scores were similar for 3 of the 4 definitions, suggesting that stringent definitions of healthy aging offer little advantage over a more moderate one. Similar to U.S. researchers, we recommend a definition of healthy aging that incorporates measures of functional health and limiting disease as opposed to definitions requiring the absence of all disease in studies designed to assess the effect of policy initiatives on healthy aging.

  13. Statistical Inversion of Absolute Permeability in Single-phase Darcy Flow

    KAUST Repository

    Strauss, Thilo; Fan, Xiaolin; Sun, Shuyu; Khan, Taufiquar

    2015-01-01

    In this paper, we formulate the permeability inverse problem in the Bayesian framework using total variation (TV) and fp (0 < p δ 2) regularization prior. We use the Markov Chain Monte Carlo (MCMC) method for sampling the posterior distribution to solve the ill-posed inverse problem. We present simulations to estimate the distribution for each pixel for the image reconstruction of the absolute permeability.

  14. Statistical Inversion of Absolute Permeability in Single-phase Darcy Flow

    KAUST Repository

    Strauss, Thilo

    2015-06-01

    In this paper, we formulate the permeability inverse problem in the Bayesian framework using total variation (TV) and fp (0 < p δ 2) regularization prior. We use the Markov Chain Monte Carlo (MCMC) method for sampling the posterior distribution to solve the ill-posed inverse problem. We present simulations to estimate the distribution for each pixel for the image reconstruction of the absolute permeability.

  15. Estimating Twin Pair Concordance for Age of Onset

    DEFF Research Database (Denmark)

    Scheike, Thomas H; Hjelmborg, Jacob B; Holst, Klaus K

    2015-01-01

    that they will develop the disease. The aim of this contribution is to show that the standard casewise concordance and standard prevalence estimators do not work in general for age-of-onset data. We show how one can in fact do something easy and simple even with censored data. The key is to take age into account when......Twin and family data provide a key source for evaluating inheritance of specific diseases. A standard analysis of such data typically involves the computation of prevalences and different concordance measures such as the casewise concordance, that is the probability that one twin has the disease...

  16. Heading Estimation of Robot Combine Harvesters during Turning Maneuveres.

    Science.gov (United States)

    Rahman, Md Mostafizar; Ishii, Kazunobu

    2018-05-01

    Absolute heading is an important parameter for a robot combine harvester or a robot tracked combine harvester, especially while it is turning, but due to the rapid turning of robot combine harvesters, its inertial measurement unit gives a gyro measurement bias that causes heading drift. Our research goal is to estimate the absolute heading of robot combine harvesters by compensating this gyro measurement bias during non-linear turning maneuvers. A sensor fusion method like the extended Kalman filter combined with the tracked combine harvester dynamic model and sensor measurements was used to estimate the absolute heading of a robot combine harvester. Circular, sinusoidal and concave shapes were used to evaluate the estimated heading produced by the sensor fusion method. The results indicate that the estimated heading is better than measured heading which was calculated from the integration of yaw rate gyro measurements, and the root mean square errors (RMSEs) for estimated headings are smaller than the measured headings. In practics, the target of this paper is thus the estimation of a heading or absolute heading that is bias compensated, and can be further used to calculate the exact crop periphery for automatic path planning of robot combine harvesters.

  17. Size-based estimation of the status of fish stocks: simulation analysis and comparison with age-based estimations

    DEFF Research Database (Denmark)

    Kokkalis, Alexandros; Thygesen, Uffe Høgsbro; Nielsen, Anders

    , were investigated and our estimations were compared to the ICES advice. Only size-specific catch data were used, in order to emulate data limited situations. The simulation analysis reveals that the status of the stock, i.e. F/Fmsy, is estimated more accurately than the fishing mortality F itself....... Specific knowledge of the natural mortality improves the estimation more than having information about all other life history parameters. Our approach gives, at least qualitatively, an estimated stock status which is similar to the results of an age-based assessment. Since our approach only uses size...

  18. Age estimates for the late quaternary high sea-stands

    Science.gov (United States)

    Smart, Peter L.; Richards, David A.

    A database of more than 300 published alpha-counted uranium-series ages has been compiled for coral reef terraces formed by Late Pleistocene high sea-stands. The database was screened to eliminate unreliable age estimates ( {230Th }/{232Th } 5%) and those without quoted without quoted errors, and a distributed error frequency curve was produced. This curve can be considered as a finite mixture model comprising k component normal distributions each with a weighting α. By using an expectation maximising algorithm, the mean and standard deviation of the component distributions, each corresponding to a high sea level event, were estimated. Eight high sea-stands with mean and standard deviations of 129.0 ± 33.0, 123.0 ± 13.0, 102.5 ± 2.0, 81.5 ± 5.0, 61.5 ± 6.0, 50.0 ± 1.0, 40.5 ± 5.0 and 33.0 ± 2.5 ka were resolved. The standard deviations are generally larger than the values quoted for individual age estimates. Whilst this may be due to diagenetic effects, especially for the older corals, it is argued that in many cases geological evidence clearly indicates that the high stands are multiple events, often not resolvable at sites with low rates of uplift. The uranium-series dated coral-reef terrace chronology shows good agreement with independent chronologies derived for Antarctic ice cores, although the resolution for the latter is better. Agreement with orbitally-tuned deep-sea core records is also good, but it is argued that Isotope Stage 5e is not a single event, as recorded in the cores, but a multiple event spanning some 12 ka. The much earlier age for Isotope Stage 5e given by Winograd et al. (1988) is not supported by the coral reef data, but further mass-spectrometric uranium-series dating is needed to permit better chronological resolution.

  19. [Forensic age estimation in juveniles and young adults: Reducing the range of scatter in age diagnosis by combining different methods].

    Science.gov (United States)

    Schmidt, Sven; Schramm, Danilo; Ribbecke, Sebastian; Schulz, Ronald; Wittschieber, Daniel; Olze, Andreas; Vieth, Volker; Ramsthaler, H Frank; Pfischel, Klaus; Pfeiffer, Heidi; Geserick, Gunther; Schmeling, Andreas

    2016-01-01

    The dramatic rise in the number of refugees entering Germany means that age estimation for juveniles and young adults whose age is unclear but relevant to legal and official procedures has become more important than ever. Until now, whether and to what extent the combination of methods recommended by the Study Group on Forensic Age Diagnostics has resulted in a reduction of the range of scatter of the summarized age diagnosis has been unclear. Hand skeletal age, third molar mineralization stage and ossification stage of the medial clavicular epiphyses were determined for 307 individuals aged between 10 and 29 at time of death on whom autopsies were performed at the Institutes of Legal Medicine in Berlin, Frankfurt am Main and Hamburg between 2001 and 2011. To measure the range of scatter, linear regression analysis was used to calculate the standard error of estimate for each of the above methods individually and in combination. It was found that combining the above methods led to a reduction in the range of scatter. Due to various limitations of the study, the statistical parameters determined cannot, however, be used for age estimation practice.

  20. New delay-dependent absolute stability criteria for Lur'e systems with time-varying delay

    Science.gov (United States)

    Chen, Yonggang; Bi, Weiping; Li, Wenlin

    2011-07-01

    In this article, the absolute stability problem is investigated for Lur'e systems with time-varying delay and sector-bounded nonlinearity. By employing the delay fractioning idea, the new augmented Lyapunov functional is first constructed. Then, by introducing some slack matrices and by reserving the useful term when estimating the upper bound of the derivative of Lyapunov functional, the new delay-dependent absolute stability criteria are derived in terms of linear matrix inequalities. Several numerical examples are presented to show the effectiveness and the less conservativeness of the proposed method.

  1. Estimated maximal and current brain volume predict cognitive ability in old age

    Science.gov (United States)

    Royle, Natalie A.; Booth, Tom; Valdés Hernández, Maria C.; Penke, Lars; Murray, Catherine; Gow, Alan J.; Maniega, Susana Muñoz; Starr, John; Bastin, Mark E.; Deary, Ian J.; Wardlaw, Joanna M.

    2013-01-01

    Brain tissue deterioration is a significant contributor to lower cognitive ability in later life; however, few studies have appropriate data to establish how much influence prior brain volume and prior cognitive performance have on this association. We investigated the associations between structural brain imaging biomarkers, including an estimate of maximal brain volume, and detailed measures of cognitive ability at age 73 years in a large (N = 620), generally healthy, community-dwelling population. Cognitive ability data were available from age 11 years. We found positive associations (r) between general cognitive ability and estimated brain volume in youth (male, 0.28; females, 0.12), and in measured brain volume in later life (males, 0.27; females, 0.26). Our findings show that cognitive ability in youth is a strong predictor of estimated prior and measured current brain volume in old age but that these effects were the same for both white and gray matter. As 1 of the largest studies of associations between brain volume and cognitive ability with normal aging, this work contributes to the wider understanding of how some early-life factors influence cognitive aging. PMID:23850342

  2. Absolute pitch among American and Chinese conservatory students: prevalence differences, and evidence for a speech-related critical period.

    Science.gov (United States)

    Deutsch, Diana; Henthorn, Trevor; Marvin, Elizabeth; Xu, HongShuai

    2006-02-01

    Absolute pitch is extremely rare in the U.S. and Europe; this rarity has so far been unexplained. This paper reports a substantial difference in the prevalence of absolute pitch in two normal populations, in a large-scale study employing an on-site test, without self-selection from within the target populations. Music conservatory students in the U.S. and China were tested. The Chinese subjects spoke the tone language Mandarin, in which pitch is involved in conveying the meaning of words. The American subjects were nontone language speakers. The earlier the age of onset of musical training, the greater the prevalence of absolute pitch; however, its prevalence was far greater among the Chinese than the U.S. students for each level of age of onset of musical training. The findings suggest that the potential for acquiring absolute pitch may be universal, and may be realized by enabling infants to associate pitches with verbal labels during the critical period for acquisition of features of their native language.

  3. Pharmacokinetic evaluation of pamidronate after oral administration: a study on dose proportionality, absolute bioavailability, and effect of repeated administration

    DEFF Research Database (Denmark)

    Hyldstrup, Lars; Flesch, G; Hauffe, S A

    1993-01-01

    30 minutes at constant infusion rate. Repeated peroral doses (75 and 150 mg) were administered to 12 females (aged 51-70 years) for 10 consecutive days. Urinary excretion of pamidronate after peroral and i.v. administration was used for estimation of pamidronate absorption. Renal excretion...... of pamidronate ranged from 0.01% to 0.35% of dose, with mean values of 0.11, 0.16, and 0.18% for 75, 150, and 300 mg, respectively. After i.v. infusion, the renal excretion of pamidronate was 26-53% of the dose, lower than for other bisphosphonates. The absolute bioavailability was 0.31% (range 0.08-0.7%) after...

  4. Accuracy of an equation for estimating age from mandibular third molar development in a Thai population

    Energy Technology Data Exchange (ETDEWEB)

    Verochana, Karune; Prapayasatok, Sangsom; Janhom, Apirum; Mahasantipiya, Phattaranant May; Korwanich, Narumanas [Faculty of Dentistry, Chiang Mai University, Chiang Mai (Thailand)

    2016-03-15

    This study assessed the accuracy of age estimates produced by a regression equation derived from lower third molar development in a Thai population. The first part of this study relied on measurements taken from panoramic radiographs of 614 Thai patients aged from 9 to 20. The stage of lower left and right third molar development was observed in each radiograph and a modified Gat score was assigned. Linear regression on this data produced the following equation: Y=9.309+1.673 mG+0.303S (Y=age; mG=modified Gat score; S=sex). In the second part of this study, the predictive accuracy of this equation was evaluated using data from a second set of panoramic radiographs (539 Thai subjects, 9 to 24 years old). Each subject's age was estimated using the above equation and compared against age calculated from a provided date of birth. Estimated and known age data were analyzed using the Pearson correlation coefficient and descriptive statistics. Ages estimated from lower left and lower right third molar development stage were significantly correlated with the known ages (r=0.818, 0.808, respectively, P≤0.01). 50% of age estimates in the second part of the study fell within a range of error of ±1 year, while 75% fell within a range of error of ±2 years. The study found that the equation tends to estimate age accurately when individuals are 9 to 20 years of age. The equation can be used for age estimation for Thai populations when the individuals are 9 to 20 years of age.

  5. Accuracy of an equation for estimating age from mandibular third molar development in a Thai population

    International Nuclear Information System (INIS)

    Verochana, Karune; Prapayasatok, Sangsom; Janhom, Apirum; Mahasantipiya, Phattaranant May; Korwanich, Narumanas

    2016-01-01

    This study assessed the accuracy of age estimates produced by a regression equation derived from lower third molar development in a Thai population. The first part of this study relied on measurements taken from panoramic radiographs of 614 Thai patients aged from 9 to 20. The stage of lower left and right third molar development was observed in each radiograph and a modified Gat score was assigned. Linear regression on this data produced the following equation: Y=9.309+1.673 mG+0.303S (Y=age; mG=modified Gat score; S=sex). In the second part of this study, the predictive accuracy of this equation was evaluated using data from a second set of panoramic radiographs (539 Thai subjects, 9 to 24 years old). Each subject's age was estimated using the above equation and compared against age calculated from a provided date of birth. Estimated and known age data were analyzed using the Pearson correlation coefficient and descriptive statistics. Ages estimated from lower left and lower right third molar development stage were significantly correlated with the known ages (r=0.818, 0.808, respectively, P≤0.01). 50% of age estimates in the second part of the study fell within a range of error of ±1 year, while 75% fell within a range of error of ±2 years. The study found that the equation tends to estimate age accurately when individuals are 9 to 20 years of age. The equation can be used for age estimation for Thai populations when the individuals are 9 to 20 years of age

  6. Accuracy of an equation for estimating age from mandibular third molar development in a Thai population.

    Science.gov (United States)

    Verochana, Karune; Prapayasatok, Sangsom; Janhom, Apirum; Mahasantipiya, Phattaranant May; Korwanich, Narumanas

    2016-03-01

    This study assessed the accuracy of age estimates produced by a regression equation derived from lower third molar development in a Thai population. The first part of this study relied on measurements taken from panoramic radiographs of 614 Thai patients aged from 9 to 20. The stage of lower left and right third molar development was observed in each radiograph and a modified Gat score was assigned. Linear regression on this data produced the following equation: Y=9.309+1.673 mG+0.303S (Y=age; mG=modified Gat score; S=sex). In the second part of this study, the predictive accuracy of this equation was evaluated using data from a second set of panoramic radiographs (539 Thai subjects, 9 to 24 years old). Each subject's age was estimated using the above equation and compared against age calculated from a provided date of birth. Estimated and known age data were analyzed using the Pearson correlation coefficient and descriptive statistics. Ages estimated from lower left and lower right third molar development stage were significantly correlated with the known ages (r=0.818, 0.808, respectively, P≤0.01). 50% of age estimates in the second part of the study fell within a range of error of ±1 year, while 75% fell within a range of error of ±2 years. The study found that the equation tends to estimate age accurately when individuals are 9 to 20 years of age. The equation can be used for age estimation for Thai populations when the individuals are 9 to 20 years of age.

  7. Near threshold absolute TDCS: First results

    International Nuclear Information System (INIS)

    Roesel, T.; Schlemmer, P.; Roeder, J.; Frost, L.; Jung, K.; Ehrhardt, H.

    1992-01-01

    A new method, and first results for an impact energy 2 eV above the threshold of ionisation of helium, are presented for the measurement of absolute triple differential cross sections (TDCS) in a crossed beam experiment. The method is based upon measurement of beam/target overlap densities using known absolute total ionisation cross sections and of detection efficiencies using known absolute double differential cross sections (DDCS). For the present work the necessary absolute DDCS for 1 eV electrons had also to be measured. Results are presented for several different coplanar kinematics and are compared with recent DWBA calculations. (orig.)

  8. Absolute entropy of ions in methanol

    International Nuclear Information System (INIS)

    Abakshin, V.A.; Kobenin, V.A.; Krestov, G.A.

    1978-01-01

    By measuring the initial thermoelectromotive forces of chains with bromo-silver electrodes in tetraalkylammonium bromide solutions the absolute entropy of bromide-ion in methanol is determined in the 298.15-318.15 K range. The anti Ssub(Brsup(-))sup(0) = 9.8 entropy units value is used for calculation of the absolute partial molar entropy of alkali metal ions and halogenide ions. It has been found that, absolute entropy of Cs + =12.0 entropy units, I - =14.0 entropy units. The obtained ion absolute entropies in methanol at 298.15 K within 1-2 entropy units is in an agreement with published data

  9. Estimation of glandular content rate and statistical analysis of the influence of age group and compressed breast thickness on the estimated value

    International Nuclear Information System (INIS)

    Ohmori, Naoki; Ashida, Kenji; Fujita, Osamu

    2003-01-01

    Because the glandular content rate is an important factor in evaluating breast cancer detection and average glandular dose, it is important in mammography research to estimate and analyze this rate. The purpose of this study was to obtain a formula for statistical estimation of the glandular content rate, to clarify statistically the influence of age group and compressed breast thickness (CBT) on estimating the glandular content rate, and to show statistically the general relation between glandular content rate and the factors of age and CBT. The subjects were 740 Japanese women aged 20-91 years (mean±SD: 48.3±12.8 years) who had undergone mammography. In our study, the glandular content rate was statistically estimated from age group, mAs-value, and CBT when subjects underwent mammography, from a phantom simulation, and from MR images of the breast. In addition, multivariate analysis was carried to examine statistically the influence of age group and CBT on glandular content rate. The mean glandular content rate as estimated by age group was as follows: 35.6% for those in their 20s, 33.4% in the 30s, 27.5% in the 40s, 23.8% in the 50s, and 21.8% in those 60 and over. The rate for the subjects as a whole was 27.1%. This study indicated that overestimation occurred if the estimated value of the glandular content rate was not corrected in the 3D-measurement by MRI. In addition, this study showed that the statistical influence on glandular content rate was significantly larger for CBT than age. (author)

  10. RELATIVE AND ABSOLUTE DENSITY ESTIMATES OF LAND PLANARIANS (PLATYHELMINTHES, TRICLADIDA IN URBAN RAINFOREST PATCHES

    Directory of Open Access Journals (Sweden)

    FERNANDO CARBAYO

    Full Text Available ABSTRACT Land planarians (Platyhelminthes are likely important components of the soil cryptofauna, although relevant aspects of their ecology such as their density remain largely unstudied. We investigated absolute and relative densities of flatworms in three patches of secondary Brazilian Atlantic rainforest in an urban environment. Two methods of sampling were carried out, one consisting of 90 hours of active search in delimited plots covering 6,000 m² over a year, and the other consisting of leaf litter extraction from a 60 m² soil area, totaling 480-600 l leaf litter. We found 288 specimens of 16 species belonging to the genera Geobia, Geoplana, Issoca, Luteostriata, Obama, Paraba, Pasipha, Rhynchodemus, Xerapoa, and the exotic species Bipalium kewense and Dolichoplana striata. Specimens up to 10 mm long were mostly sampled only with the leaf litter extraction method. Absolute densities, calculated from data obtained with leaf litter extraction, ranged between 1.25 and 2.10 individuals m-2. These values are 30 to 161 times higher than relative densities, calculated from data obtained by active search. Since most common sampling method used in land planarian studies on species composition and faunal inventories is active search for a few hours in a locality, our results suggest that small species might be overlooked. It remains to be tested whether similar densities of this cryptofauna are also found in primary forests.

  11. Estimating age from recapture data: integrating incremental growth measures with ancillary data to infer age-at-length

    Science.gov (United States)

    Eaton, Mitchell J.; Link, William A.

    2011-01-01

    Estimating the age of individuals in wild populations can be of fundamental importance for answering ecological questions, modeling population demographics, and managing exploited or threatened species. Significant effort has been devoted to determining age through the use of growth annuli, secondary physical characteristics related to age, and growth models. Many species, however, either do not exhibit physical characteristics useful for independent age validation or are too rare to justify sacrificing a large number of individuals to establish the relationship between size and age. Length-at-age models are well represented in the fisheries and other wildlife management literature. Many of these models overlook variation in growth rates of individuals and consider growth parameters as population parameters. More recent models have taken advantage of hierarchical structuring of parameters and Bayesian inference methods to allow for variation among individuals as functions of environmental covariates or individual-specific random effects. Here, we describe hierarchical models in which growth curves vary as individual-specific stochastic processes, and we show how these models can be fit using capture–recapture data for animals of unknown age along with data for animals of known age. We combine these independent data sources in a Bayesian analysis, distinguishing natural variation (among and within individuals) from measurement error. We illustrate using data for African dwarf crocodiles, comparing von Bertalanffy and logistic growth models. The analysis provides the means of predicting crocodile age, given a single measurement of head length. The von Bertalanffy was much better supported than the logistic growth model and predicted that dwarf crocodiles grow from 19.4 cm total length at birth to 32.9 cm in the first year and 45.3 cm by the end of their second year. Based on the minimum size of females observed with hatchlings, reproductive maturity was estimated

  12. Estimation of Correlation between Chronological Age, Skeletal Age and Dental Age in Children- A Cross-sectional Study.

    Science.gov (United States)

    Macha, Madhulika; Lamba, Bharti; Avula, Jogendra Sai Sankar; Muthineni, Sridhar; Margana, Pratap Gowd Jai Shankar; Chitoori, Prasad

    2017-09-01

    In the modern era, identification and determination of age is imperative for diversity of reasons that include disputed birth records, premature delivery, legal issues and for validation of birth certificate for school admissions, adoption, marriage, job and immigration. Several growth assessment parameters like bone age, dental age and the combination of both have been applied for different population with variable outcomes. It has been well documented that the chronological age does not necessarily correlate with the maturational status of a child. Hence, efforts were made to determine a child's developmental age by using dental age (calcification of teeth) and skeletal age (skeletal maturation). The present study was aimed to correlate the chronological age, dental age and skeletal age in children from Southeastern region of Andhra Pradesh, India. Out of the total 900 screened children, only 100 subjects between age groups of 6-14 years with a mean age of 11.3±2.63 for males and 10.77±2.24 for females were selected for the study. Dental age was calculated by Demirjian method and skeletal age by modified Middle Phalanx of left hand third finger (MP3) method. Pearson's and Spearman's correlation tests were done to estimate the correlation between chronological, dental and skeletal ages among study population. There was a significant positive correlation between chronological age, dental age and all stages of MP3 among males. Similar results were observed in females, except for a non-significant moderate correlation between chronological age and dental age in the H stage of the MP3 region. The results of the present study revealed correlation with statistical significance (p<0.05) between chronological, dental and skeletal ages among all the subjects (48 males and 52 females) and females attained maturity earlier than males in the present study population.

  13. Absolute and Relative Socioeconomic Health Inequalities across Age Groups

    NARCIS (Netherlands)

    van Zon, Sander K. R.; Bultmann, Ute; de Leon, Carlos F. Mendes; Reijneveld, Sijmen A.

    2015-01-01

    Background The magnitude of socioeconomic health inequalities differs across age groups. It is less clear whether socioeconomic health inequalities differ across age groups by other factors that are known to affect the relation between socioeconomic position and health, like the indicator of

  14. Is Greulich–Pyle age estimation applicable for determining maturation in male Africans?

    OpenAIRE

    Alan G. Morri; Kundisai A. Dembetembe

    2012-01-01

    Skeletal age estimation as a means of assessing development and skeletal maturation in children and adolescents is of great importance for clinical and forensic purposes. The skeletal age of a test population is estimated by comparison with established standards, the most common standards being those in the Radiographic atlas of skeletal development of the hand and wristpublished by Greulich and Pyle in 1959. These standards are based on the assumption that skeletal maturity in male individua...

  15. Precision and accuracy of commonly used dental age estimation charts for the New Zealand population.

    Science.gov (United States)

    Baylis, Stephanie; Bassed, Richard

    2017-08-01

    Little research has been undertaken for the New Zealand population in the field of dental age estimation. This research to date indicates there are differences in dental developmental rates between the New Zealand population and other global population groups, and within the New Zealand population itself. Dental age estimation methods range from dental development charts to complex biometric analysis. Dental development charts are not the most accurate method of dental age estimation, but are time saving in their use. They are an excellent screening tool, particularly for post-mortem identification purposes, and for assessing variation from population norms in living individuals. The aim of this study was to test the precision and accuracy of three dental development charts (Schour and Massler, Blenkin and Taylor, and the London Atlas), used to estimate dental age of a sample of New Zealand juveniles between the ages of 5 and 18 years old (n=875). Percentage 'best fit' to correct age category and to expected chart stage were calculated to determine which chart was the most precise for the sample. Chronological ages were compared to estimated dental ages using a two-tailed paired t-test (Pcharts tested against the New Zealand population sample, the Blenkin and Taylor Australian charts performed best overall. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Heading Estimation of Robot Combine Harvesters during Turning Maneuveres

    Directory of Open Access Journals (Sweden)

    Md Mostafizar Rahman

    2018-05-01

    Full Text Available Absolute heading is an important parameter for a robot combine harvester or a robot tracked combine harvester, especially while it is turning, but due to the rapid turning of robot combine harvesters, its inertial measurement unit gives a gyro measurement bias that causes heading drift. Our research goal is to estimate the absolute heading of robot combine harvesters by compensating this gyro measurement bias during non-linear turning maneuvers. A sensor fusion method like the extended Kalman filter combined with the tracked combine harvester dynamic model and sensor measurements was used to estimate the absolute heading of a robot combine harvester. Circular, sinusoidal and concave shapes were used to evaluate the estimated heading produced by the sensor fusion method. The results indicate that the estimated heading is better than measured heading which was calculated from the integration of yaw rate gyro measurements, and the root mean square errors (RMSEs for estimated headings are smaller than the measured headings. In practics, the target of this paper is thus the estimation of a heading or absolute heading that is bias compensated, and can be further used to calculate the exact crop periphery for automatic path planning of robot combine harvesters.

  17. Accuracy of the estimation of dental age in comparison with chronological age in a Spanish sample of 2641 living subjects using the Demirjian and Nolla methods.

    Science.gov (United States)

    Melo, María; Ata-Ali, Javier

    2017-01-01

    Age estimation is an important procedure in forensic medicine and is carried out for a number of reasons. For living persons, age estimation is performed in order to assess whether a child has attained the age of criminal responsibility, in scenarios involving rape, kidnapping or marriage, in premature births, adoption procedures, illegal immigration, pediatric endocrine diseases and orthodontic malocclusion, as well as in circumstances in which the birth certificate is not available or the records are suspect. According to data from the UNHCR (United Nations High Commissioner for Refugees), the number of people seeking refugee status continued to increase in the last years, driven by the wars in Syria and Iraq, as well as by conflict and instability in Afghanistan, Eritrea and elsewhere. The objective of this study is to compare the accuracy of estimating dental age versus chronological age using the Nolla and Demirjian methods in a Spanish population. A final sample of 2641 panoramic X-rays corresponding to Spanish patients (1322 males and 1319 females) between 7-21 years of age was analyzed. Dental age was assessed using the Nolla and Demirjian methods, establishing comparisons with mean chronological age based on the Student t-test for paired samples, followed by the generation of a linear regression model. Both methods showed slight discrepancy between dental and chronological age. On examining the reproducibility of the Nolla and Demirjian methods, technical errors of 0.84% and 0.62%, respectively, were observed. On average, the Nolla method was found to estimate an age 0.213years younger than the chronological age, while the Demirjian method estimated an age 0.853years older than the chronological age. Linear combination of the mean Nolla and Demirjian estimates increased the predictive capacity to 99.2%. In conclusion the Nolla and Demirjian methods were found to be accurate in estimating chronological age from dental age in a Spanish population. The error

  18. Gene expression during blow fly development: improving the precision of age estimates in forensic entomology.

    Science.gov (United States)

    Tarone, Aaron M; Foran, David R

    2011-01-01

    Forensic entomologists use size and developmental stage to estimate blow fly age, and from those, a postmortem interval. Since such estimates are generally accurate but often lack precision, particularly in the older developmental stages, alternative aging methods would be advantageous. Presented here is a means of incorporating developmentally regulated gene expression levels into traditional stage and size data, with a goal of more precisely estimating developmental age of immature Lucilia sericata. Generalized additive models of development showed improved statistical support compared to models that did not include gene expression data, resulting in an increase in estimate precision, especially for postfeeding third instars and pupae. The models were then used to make blind estimates of development for 86 immature L. sericata raised on rat carcasses. Overall, inclusion of gene expression data resulted in increased precision in aging blow flies. © 2010 American Academy of Forensic Sciences.

  19. Absolute calibration of the neutron yield measurement on JT-60 Upgrade

    International Nuclear Information System (INIS)

    Nishitani, Takeo; Takeuchi, Hiroshi; Barnes, C.W.

    1991-10-01

    Absolutely calibrated measurements of the neutron yield are important for the evaluation of the plasma performance such as the fusion gain Q in DD operating tokamaks. Total neutron yield is measured with 235 U and 238 U fission chambers and 3 He proportional counters in JT-60 Upgrade. The in situ calibration was performed by moving the 252 Cf neutron source toroidally through the JT-60 vacuum vessel. Detection efficiencies of three 235 U and two 3 He detectors were measured for 92 locations of the neutron point source in toroidal scans at two different major radii. The total detection efficiency for the torus neutron source was obtained by averaging the point efficiencies over the whole toroidal angle. The uncertainty of the resulting absolute plasma neutron source calibration is estimated to be ± 10%. (author)

  20. Age estimation of living Indian individuals based on aspartic acid racemization from tooth biopsy specimen

    Science.gov (United States)

    Rastogi, Manu; Logani, Ajay; Shah, Naseem; Kumar, Abhishek; Arora, Saurabh

    2017-01-01

    Background: Age estimation in living individuals is imperative to amicably settle civil and criminal disputes. A biochemical method based on amino acid racemization was evaluated for age estimation of living Indian individuals. Design: Caries-free maxillary/mandibular premolar teeth (n = 90) were collected from participants with age proof documents and divided into predefined nine age groups. Materials and Methods: Dentine biopsy from the labial aspect of the tooth crown was taken with an indigenously developed microtrephine. The samples were processed and subjected to gas chromatography. Dextrorotatory:levorotatory ratios were calculated, and a regression equation was formulated. Results: Across all age groups, an error of 0 ± 4 years between protein racemization age and chronological age was observed. Conclusion: Aspartic acid racemization from dentine biopsy samples could be a viable and accurate technique for age estimation of living individuals who have attained a state of skeletal maturity. PMID:29263613

  1. On the Use of the Main-sequence Knee (Saddle) to Measure Globular Cluster Ages

    Science.gov (United States)

    Saracino, S.; Dalessandro, E.; Ferraro, F. R.; Lanzoni, B.; Origlia, L.; Salaris, M.; Pietrinferni, A.; Geisler, D.; Kalirai, J. S.; Correnti, M.; Cohen, R. E.; Mauro, F.; Villanova, S.; Moni Bidin, C.

    2018-06-01

    In this paper, we review the operational definition of the so-called main-sequence knee (MS-knee), a feature in the color-magnitude diagram (CMD) occurring at the low-mass end of the MS. The magnitude of this feature is predicted to be independent of age at fixed chemical composition. For this reason, its difference in magnitude with respect to the MS turn-off (MS-TO) point has been suggested as a possible diagnostic to estimate absolute globular cluster (GC) ages. We first demonstrate that the operational definition of the MS-knee currently adopted in the literature refers to the inflection point of the MS (which we here more appropriately named MS-saddle), a feature that is well distinct from the knee and which cannot be used as its proxy. The MS-knee is only visible in near-infrared CMDs, while the MS-saddle can be also detected in optical–NIR CMDs. By using different sets of isochrones, we then demonstrate that the absolute magnitude of the MS-knee varies by a few tenths of a dex from one model to another, thus showing that at the moment stellar models may not capture the full systematic error in the method. We also demonstrate that while the absolute magnitude of the MS-saddle is almost coincident in different models, it has a systematic dependence on the adopted color combinations which is not predicted by stellar models. Hence, it cannot be used as a reliable reference for absolute age determination. Moreover, when statistical and systematic uncertainties are properly taken into account, the difference in magnitude between the MS-TO and the MS-saddle does not provide absolute ages with better accuracy than other methods like the MS-fitting.

  2. Application of X-rays to dental age estimation in medico-legal practice

    Directory of Open Access Journals (Sweden)

    Dorota Lorkiewicz-Muszyńska

    2015-05-01

    Full Text Available Aim of the study: The paper addresses the use of dental age assessment methods based on radiographs in medico-legal practice. Different cases of practical application of the methods are presented including identification of human remains, dental age assessment in a living person and one archaeological case. Material and methods : The study material consisted of cases involving dental age assessment performed in the Department of Forensic Medicine, Poznan University of Medical Sciences in Poznan. Depending on the preliminary assessment of age, the Liversidge or the Kvaal et al. methods were applied. Dental age was estimated on the basis of available pantomograms. In the case of the living person, it was a radiograph supplied for expert evaluation. In the other cases, dental computed tomography was performed. Results : Dental age was successfully estimated in all of the cases. Various methods based on the analysis of X-ray images were applied. Dental age was shown to be correlated with skeletal age. Conclusions : The methods based on radiographs were demonstrated to be useful, and the results they yield are fully correlated with results of anthropological analyses.

  3. Projective absoluteness for Sacks forcing

    NARCIS (Netherlands)

    Ikegami, D.

    2009-01-01

    We show that Sigma(1)(3)-absoluteness for Sacks forcing is equivalent to the nonexistence of a Delta(1)(2) Bernstein set. We also show that Sacks forcing is the weakest forcing notion among all of the preorders that add a new real with respect to Sigma(1)(3) forcing absoluteness.

  4. Forecasting Error Calculation with Mean Absolute Deviation and Mean Absolute Percentage Error

    Science.gov (United States)

    Khair, Ummul; Fahmi, Hasanul; Hakim, Sarudin Al; Rahim, Robbi

    2017-12-01

    Prediction using a forecasting method is one of the most important things for an organization, the selection of appropriate forecasting methods is also important but the percentage error of a method is more important in order for decision makers to adopt the right culture, the use of the Mean Absolute Deviation and Mean Absolute Percentage Error to calculate the percentage of mistakes in the least square method resulted in a percentage of 9.77% and it was decided that the least square method be worked for time series and trend data.

  5. Bias correction of nutritional status estimates when reported age is used for calculating WHO indicators in children under five years of age.

    Science.gov (United States)

    Quezada, Amado D; García-Guerra, Armando; Escobar, Leticia

    2016-06-01

    To assess the performance of a simple correction method for nutritional status estimates in children under five years of age when exact age is not available from the data. The proposed method was based on the assumption of symmetry of age distributions within a given month of age and validated in a large population-based survey sample of Mexican preschool children. The main distributional assumption was consistent with the data. All prevalence estimates derived from the correction method showed no statistically significant bias. In contrast, failing to correct attained age resulted in an underestimation of stunting in general and an overestimation of overweight or obesity among the youngest. The proposed method performed remarkably well in terms of bias correction of estimates and could be easily applied in situations in which either birth or interview dates are not available from the data.

  6. Residual lifetime and 10 year absolute risks of osteoporotic fractures in Chinese men and women.

    Science.gov (United States)

    Si, Lei; Winzenberg, Tania M; Chen, Mingsheng; Jiang, Qicheng; Palmer, Andrew J

    2015-06-01

    To determine the residual lifetime and 10 year absolute risks of osteoporotic fractures in Chinese men and women. A validated state-transition microsimulation model was used. Microsimulation and probabilistic sensitivity analyses were performed to address the uncertainties in the model. All parameters including fracture incidence rates and mortality rates were retrieved from published literature. Simulated subjects were run through the model until they died to estimate the residual lifetime fracture risks. A 10 year time horizon was used to determine the 10 year fracture risks. We estimated the risk of only the first osteoporotic fracture during the simulation time horizon. The residual lifetime and 10 year risks of having the first osteoporotic (hip, clinical vertebral or wrist) fracture for Chinese women aged 50 years were 40.9% (95% CI: 38.3-44.0%) and 8.2% (95% CI: 6.8-9.3%) respectively. For men, the residual lifetime and 10 year fracture risks were 8.7% (95% CI: 7.5-9.8%) and 1.2% (95% CI: 0.8-1.7%) respectively. The residual lifetime fracture risks declined with age, whilst the 10 year fracture risks increased with age until the short-term mortality risks outstripped the fracture risks. Residual lifetime and 10 year clinical vertebral fracture risks were higher than those of hip and wrist fractures in both sexes. More than one third of the Chinese women and approximately one tenth of the Chinese men aged 50 years are expected to sustain a major osteoporotic fracture in their remaining lifetimes. Due to increased fracture risks and a rapidly ageing population, osteoporosis will present a great challenge to the Chinese healthcare system. While national data was used wherever possible, regional Chinese hip and clinical vertebral fracture incidence rates were used, wrist fracture rates were taken from a Norwegian study and calibrated to the Chinese population. Other fracture sites like tibia, humerus, ribs and pelvis were not included in the analysis, thus these

  7. Human dental age estimation combining third molar(s) development and tooth morphological age predictors.

    Science.gov (United States)

    Thevissen, P W; Galiti, D; Willems, G

    2012-11-01

    In the subadult age group, third molar development, as well as age-related morphological tooth information can be observed on panoramic radiographs. The aim of present study was to combine, in subadults, panoramic radiographic data based on developmental stages of third molar(s) and morphological measurements from permanent teeth, in order to evaluate its added age-predicting performances. In the age range between 15 and 23 years, 25 gender-specific radiographs were collected within each age category of 1 year. Third molar development was classified and registered according the 10-point staging and scoring technique proposed by Gleiser and Hunt (1955), modified by Köhler (1994). The Kvaal (1995) measuring technique was applied on the indicated teeth from the individuals' left side. Linear regression models with age as response and third molar-scored stages as explanatory variables were developed, and morphological measurements from permanent teeth were added. From the models, determination coefficients (R (2)) and root-mean-square errors (RMSE) were calculated. Maximal-added age information was reported as a 6 % R² increase and a 0.10-year decrease of RMSE. Forensic dental age estimations on panoramic radiographic data in the subadult group (15-23 year) should only be based on third molar development.

  8. Human age estimation combining third molar and skeletal development.

    Science.gov (United States)

    Thevissen, P W; Kaur, J; Willems, G

    2012-03-01

    The wide prediction intervals obtained with age estimation methods based on third molar development could be reduced by combining these dental observations with age-related skeletal information. Therefore, on cephalometric radiographs, the most accurate age-estimating skeletal variable and related registration method were searched and added to a regression model, with age as response and third molar stages as explanatory variable. In a pilot set up on a dataset of 496 (283 M; 213 F) cephalometric radiographs, the techniques of Baccetti et al. (2005) (BA), Seedat et al. (2005) (SE), Caldas et al. (2007) and Rai et al. (2008) (RA) were verified. In the main study, data from 460 (208 F, 224 M) individuals in an age range between 3 and 26 years, for which at the same day an orthopantogram and a cephalogram were taken, were collected. On the orthopantomograms, the left third molar development was registered using the scoring system described by Gleiser and Hunt (1955) and modified by Köhler (1994) (GH). On the cephalograms, cervical vertebrae development was registered according to the BA and SE techniques. A regression model, with age as response and the GH scores as explanatory variable, was fitted to the data. Next, information of BA, SE and BA + SE was, respectively, added to this model. From all obtained models, the determination coefficients and the root mean squared errors were calculated. Inclusion of information from cephalograms based on the BA, as well as the SE, technique improved the amount of explained variance in age acquired from panoramic radiographs using the GH technique with 48%. Inclusion of cephalometric BA + SE information marginally improved the previous result (+1%). The RMSE decreased with 1.93, 1.85 and 2.03 years by adding, respectively, BA, SE and BA + SE information to the GH model. The SE technique allows clinically the fastest and easiest registration of the degree of development of the cervical vertebrae. Therefore, the choice of

  9. Point-of-care estimation of haemoglobin concentration in all age ...

    African Journals Online (AJOL)

    Point-of-care estimation of haemoglobin concentration in all age groups in clinical ... and the results were compared using standard scatter and difference plots. ... Hb measurements with a smaller sample volume, improved turnaround time, ...

  10. Combining near-subject absolute and relative measures of longitudinal hydration in hemodialysis.

    Science.gov (United States)

    Chan, Cian; McIntyre, Christopher; Smith, David; Spanel, Patrik; Davies, Simon J

    2009-11-01

    The feasibility and additional value of combining bioimpedance analysis (BIA) with near-subject absolute measurement of total body water using deuterium dilution (TBW(D)) in determining longitudinal fluid status was investigated. Fifty-nine hemodialysis patients (17 female; age 58.4 +/- 16.1 yr; body mass index 27.0 +/- 5.4) were enrolled into a 12-mo, two-center, prospective cohort study. Deuterium concentration was measured in breath by flowing-afterglow mass spectrometry using a validated protocol ensuring full equilibration with the TBW; BIA was measured using a multifrequency, multisegmental device. Comorbidity was quantified by the Stoke score. Clinicians were blinded to body composition data. At baseline and 12 mo, there was an incremental discrepancy between TBW(BIA) and TBW(D) volumes such that greater comorbidity was associated with increasing overhydration. Forty-three patients who completed the study had no longitudinal differences in the prescribed or achieved postdialysis weights. In contrast, TBW(D) increased without a change in TBW(BIA) (mean difference -0.10 L). Changes in TBW and lean body mass differed according to baseline comorbidity; without comorbidity, BIA also identified an increase in TBW and lean body mass, whereas with increasing comorbid burden, BIA failed to demonstrate increases in tissue hydration identified by TBW(D). Combined near-patient measurements of absolute and BIA-estimated TBW are achievable in a dialysis facility by identifying changes in body composition not fully appreciated by routine assessment. BIA underestimates tissue overhydration that is associated with comorbidity, resulting in reduced sensitivity to longitudinal increases during a 12-mo period.

  11. Comparison of the effectiveness of phalanges vs. humeri and femurs to estimate lizard age with skeletochronology

    Energy Technology Data Exchange (ETDEWEB)

    Comas, M.; Reguera, S.; Zamora-Camacho, F.J.; Salvado, H.; Moreno-Rueda, G.

    2016-07-01

    Skeletochronology allows estimation of lizard age with a single capture (from a bone), making long–term monitoring unnecessary. Nevertheless, this method often involves the death of the animal to obtain the bone. We tested the reliability of skeletochronology of phalanges (which may be obtained without killing) by comparing the estimated age from femurs and humeri with the age estimated from phalanges. Our results show skeletochronology of phalanges is a reliable method to estimate age in lizards as cross–section readings from all bones studied presented a high correlation and repeatability regardless of the bone chosen. This approach provides an alternative to the killing of lizards for skeletochronology studies. (Author)

  12. Comparison of the effectiveness of phalanges vs. humeri and femurs to estimate lizard age with skeletochronology

    International Nuclear Information System (INIS)

    Comas, M.; Reguera, S.; Zamora-Camacho, F.J.; Salvado, H.; Moreno-Rueda, G.

    2016-01-01

    Skeletochronology allows estimation of lizard age with a single capture (from a bone), making long–term monitoring unnecessary. Nevertheless, this method often involves the death of the animal to obtain the bone. We tested the reliability of skeletochronology of phalanges (which may be obtained without killing) by comparing the estimated age from femurs and humeri with the age estimated from phalanges. Our results show skeletochronology of phalanges is a reliable method to estimate age in lizards as cross–section readings from all bones studied presented a high correlation and repeatability regardless of the bone chosen. This approach provides an alternative to the killing of lizards for skeletochronology studies. (Author)

  13. Age estimation by canines' pulp/tooth ratio in an Iranian population using digital panoramic radiography.

    Science.gov (United States)

    Dehghani, Mahdieh; Shadkam, Elaheh; Ahrari, Farzaneh; Dehghani, Mahboobe

    2018-04-01

    Age estimation in adults is an important issue in forensic science. This study aimed to estimate the chronological age of Iranians by means of pulp/tooth area ratio (AR) of canines in digital panoramic radiographs. The sample consisted of panoramic radiographs of 271 male and female subjects aged 16-64 years. The pulp/tooth area ratio (AR) of upper and lower canines was calculated by AutoCAD software. Data were subjected to correlation and regression analysis. There was a significant and inverse correlation between age and pulp/tooth area ratio of upper and lower canines (r=-0.794 for upper canine and r=-0.282 for lower canine; p-value<0.001). Linear regression equations were derived separately for upper, lower and both canines. The mean difference between actual and estimated age using upper canine was 6.07±1.7. The results showed that the pulp/tooth area ratios of canines are a reliable method for age estimation in Iranians. The pulp/tooth area ratio of upper canine was better correlated with chronological age than that of lower canine. Copyright © 2018 Elsevier B.V. All rights reserved.

  14. Age estimation, growth rate and size at sexual maturity of tigerfish ...

    African Journals Online (AJOL)

    A total of 206 tigerfish Hydrocynus vittatus, collected by angling in August 2005, 2006 and 2007, was assessed for sexual maturity and relative ages were estimated from 135 of these, using scales and whole and sectioned otoliths. Sectioned otoliths were the most appropriate method for ageing H. vittatus of up to 20 years ...

  15. Age estimation by 3D CT-scans of the Borremose Woman, a Danish bog body

    DEFF Research Database (Denmark)

    Villa, Chiara; Møller Rasmussen, Maria; Lynnerup, Niels

    2011-01-01

    Non-invasive estimation of age at death has been carried out by using 3D CT scanning of a bog body discovered in 1948 in a peat bog in Borremose (Denmark). The bog body has been dated to the 8th century BC, in the last part of the Bronze Age. The skeletal structures useful for age estimation have...

  16. Demirjian's method in the estimation of age: A study on human third molars.

    Science.gov (United States)

    Lewis, Amitha J; Boaz, Karen; Nagesh, K R; Srikant, N; Gupta, Neha; Nandita, K P; Manaktala, Nidhi

    2015-01-01

    The primary aim of the following study is to estimate the chronological age based on the stages of third molar development following the eight stages (A to H) method of Demirjian et al. (along with two modifications-Orhan) and secondary aim is to compare third molar development with sex and age. The sample consisted of 115 orthopantomograms from South Indian subjects with known chronological age and gender. Multiple regression analysis was performed with chronological age as the dependable variable and third molar root development as independent variable. All the statistical analysis was performed using the SPSS 11.0 package (IBM ® Corporation). Statistically no significant differences were found in third molar development between males and females. Depending on the available number of wisdom teeth in an individual, R (2) varied for males from 0.21 to 0.48 and for females from 0.16 to 0.38. New equations were derived for estimating the chronological age. The chronological age of a South Indian individual between 14 and 22 years may be estimated based on the regression formulae. However, additional studies with a larger study population must be conducted to meet the need for population-based information on third molar development.

  17. Bias correction of nutritional status estimates when reported age is used for calculating WHO indicators in children under five years of age

    Directory of Open Access Journals (Sweden)

    Amado D Quezada

    2016-05-01

    Full Text Available Objective.To assess the performance of a simple correction method for nutritional status estimates in children under five years of age when exact age is not available from the data. Materials and methods. The proposed method was ba- sed on the assumption of symmetry of age distributions within a given month of age and validated in a large population-based survey sample of Mexican preschool children. Results. The main distributional assumption was consistent with the data. All prevalence estimates derived from the correction method showed no statistically significant bias. In contrast, failing to correct attained age resulted in an underestimation of stunting in general and an overestimation of overweight or obesity among the youngest. Conclusions. The proposed method performed remarkably well in terms of bias correction of estimates and could be easily applied in situations in which either birth or interview dates are not available from the data.

  18. Long term observation on absolute lymphocyte counts in the adult health study sample, Hiroshima and Nagasaki

    International Nuclear Information System (INIS)

    Oesterle, S.N.; Norman, J.E. Jr.

    1980-01-01

    Total peripheral blood lymphocytes were evaluated by age and exposure status in the Adult Health Study population during three examination cycles between 1958 and 1972. No radiation effect was observed, but a significant drop in the absolute lymphocyte counts of those aged 70 years and over and a corresponding maximum for persons aged 50 - 59 was observed. (author)

  19. Estimation of sex and age of 'virtual skeletons'-a feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Grabherr, Silke [University Hospital of Lausanne, Institute of Forensic Medicine, Lausanne (Switzerland)]|[University of Bern, Institute of Forensic Medicine, Bern (Switzerland)]|[University Hospital of Lausanne, Service of Diagnostic and Interventional Radiology, Lausanne (Switzerland); Cooper, Christine; Ulrich-Bochsler, Susi [University of Bern, Institute for the History of Medicine, Historical Anthropology, Bern (Switzerland); Uldin, Tanya [Service of Osteo-Archaeology, Aesch (Switzerland); Ross, Steffen; Oesterhelweg, Lars; Bolliger, Stephan; Thali, Michael J. [University of Bern, Institute of Forensic Medicine, Bern (Switzerland); Christe, Andreas [University of Bern, Institute of Forensic Medicine, Bern (Switzerland)]|[University of Bern, Institute of Diagnostic Radiology, Bern (Switzerland); Schnyder, Pierre [University Hospital of Lausanne, Service of Diagnostic and Interventional Radiology, Lausanne (Switzerland); Mangin, Patrice [University Hospital of Lausanne, Institute of Forensic Medicine, Lausanne (Switzerland)

    2009-02-15

    This article presents a feasibility study with the objective of investigating the potential of multi-detector computed tomography (MDCT) to estimate the bone age and sex of deceased persons. To obtain virtual skeletons, the bodies of 22 deceased persons with known age at death were scanned by MDCT using a special protocol that consisted of high-resolution imaging of the skull, shoulder girdle (including the upper half of the humeri), the symphysis pubis and the upper halves of the femora. Bone and soft-tissue reconstructions were performed in two and three dimensions. The resulting data were investigated by three anthropologists with different professional experience. Sex was determined by investigating three-dimensional models of the skull and pelvis. As a basic orientation for the age estimation, the complex method according to Nemeskeri and co-workers was applied. The final estimation was effected using additional parameters like the state of dentition, degeneration of the spine, etc., which where chosen individually by the three observers according to their experience. The results of the study show that the estimation of sex and age is possible by the use of MDCT. Virtual skeletons present an ideal collection for anthropological studies, because they are obtained in a non-invasive way and can be investigated ad infinitum. (orig.)

  20. Relationships between central arterial stiffness, lean body mass, and absolute and relative strength in young and older men and women.

    Science.gov (United States)

    Fahs, Christopher A; Thiebaud, Robert S; Rossow, Lindy M; Loenneke, Jeremy P; Bemben, Debra A; Bemben, Michael G

    2017-08-16

    Relationships between muscular strength and arterial stiffness as well as between muscle mass and arterial stiffness have been observed suggesting a link between the neuromuscular system and vascular health. However, the relationship between central arterial stiffness and absolute and relative strength along with muscle mass has not been investigated in both sexes across a broad age range. The purpose of this study was to examine the relationship between central arterial stiffness and absolute and relative strength as well as between central arterial stiffness and lean body mass (LBM) in men and women across a broad age range. LBM, central arterial stiffness and strength were measured on 36 men and 35 women between the ages of 18 and 75 years. Strength was measured on five machine resistance exercises and summed as one measure of overall strength (absolute strength). Relative strength was calculated as total strength divided by LBM (relative strength). Central arterial stiffness was inversely related to both absolute (r = -0·230; P = 0·029) and relative strength (r = -0·484; P LBM (r = 0·097; P = 0·213). The relationship between central arterial stiffness and relative strength was attenuated but still present when controlling for either age, per cent body fat, LBM or mean arterial pressure. These results suggest that, across a wide age range, the expression of relative muscular strength has a stronger relationship with central arterial stiffness compared to either LBM or absolute strength. This suggests that muscle function more than muscle mass may be coupled with vascular health. © 2017 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  1. Specific and unspecific gynecological alarm symptoms -prevalence estimates in different age groups

    DEFF Research Database (Denmark)

    Balasubramaniam, Kirubakaran; Ravn, Pernille; Larsen, Pia V

    2015-01-01

    OBJECTIVE: To determine prevalence estimates of gynecological alarm symptoms in different age groups and to describe common patterns of gynecological symptoms. DESIGN: Web-based cross-sectional survey study. SETTING: Nationwide in Denmark. POPULATION: A random sample of 51 090 women aged 20 years...

  2. Dynamically consistent hydrography and absolute velocity in the eastern North Atlantic Ocean

    Science.gov (United States)

    Wunsch, Carl

    1994-01-01

    The problem of mapping a dynamically consistent hydrographic field and associated absolute geostrophic flow in the eastern North Atlantic between 24 deg and 36 deg N is related directly to the solution of the so-called thermocline equations. A nonlinear optimization problem involving Needler's P equation is solved to find the hydrography and resulting flow that minimizes the vertical mixing above about 1500 m in the ocean and is simultaneously consistent with the observations. A sharp minimum (at least in some dimensions) is found, apparently corresponding to a solution nearly conserving potential vorticity and with vertical eddy coefficient less than about 10(exp -5) sq m/s. Estimates of `residual' quantities such as eddy coefficients are extremely sensitive to slight modifications to the observed fields. Boundary conditions, vertical velocities, etc., are a product of the optimization and produce estimates differing quantitatively from prior ones relying directly upon observed hydrography. The results are generally insensitive to particular elements of the solution methodology, but many questions remain concerning the extent to which different synoptic sections can be asserted to represent the same ocean. The method can be regarded as a practical generalization of the beta spiral and geostrophic balance inverses for the estimate of absolute geostrophic flows. Numerous improvements to the methodology used in this preliminary attempt are possible.

  3. Estimation of component redundancy in optimal age maintenance

    OpenAIRE

    Siopa, Jorge; Garção, José; Silva, Júlio

    2012-01-01

    The classical Optimal Age-Replacement defines the maintenance strategy based on the equipment failure consequences. For severe consequences an early equipment replacement is recommended. For minor consequences the repair after failure is proposed. One way of reducing the failure consequences is the use of redundancies, especially if the equipment failure rate is decreasing over time, since in this case the preventive replacement does not reduce the risk of failure. The estimation of an ac...

  4. The absolute chronology and thermal processing of solids in the solar protoplanetary disk

    DEFF Research Database (Denmark)

    Connelly, James; Bizzarro, Martin; Krot, Alexander N.

    2012-01-01

    Transient heating events that formed calcium-aluminum - rich inclusions (CAIs) and chondrules are fundamental processes in the evolution of the solar protoplanetary disk, but their chronology is not understood. Using U-corrected Pb-Pb dating, we determined absolute ages of individual CAIs and cho...

  5. Entrenched geographical and socioeconomic disparities in child mortality: trends in absolute and relative inequalities in Cambodia.

    Directory of Open Access Journals (Sweden)

    Eliana Jimenez-Soto

    Full Text Available BACKGROUND: Cambodia has made considerable improvements in mortality rates for children under the age of five and neonates. These improvements may, however, mask considerable disparities between subnational populations. In this paper, we examine the extent of the country's child mortality inequalities. METHODS: Mortality rates for children under-five and neonates were directly estimated using the 2000, 2005 and 2010 waves of the Cambodian Demographic Health Survey. Disparities were measured on both absolute and relative scales using rate differences and ratios, and where applicable, slope and relative indices of inequality by levels of rural/urban location, regions and household wealth. FINDINGS: Since 2000, considerable reductions in under-five and to a lesser extent in neonatal mortality rates have been observed. This mortality decline has, however, been accompanied by an increase in relative inequality in both rates of child mortality for geography-related stratifying markers. For absolute inequality amongst regions, most trends are increasing, particularly for neonatal mortality, but are not statistically significant. The only exception to this general pattern is the statistically significant positive trend in absolute inequality for under-five mortality in the Coastal region. For wealth, some evidence for increases in both relative and absolute inequality for neonates is observed. CONCLUSION: Despite considerable gains in reducing under-five and neonatal mortality at a national level, entrenched and increased geographical and wealth-based inequality in mortality, at least on a relative scale, remain. As expected, national progress seems to be associated with the period of political and macroeconomic stability that started in the early 2000s. However, issues of quality of care and potential non-inclusive economic growth might explain remaining disparities, particularly across wealth and geography markers. A focus on further addressing key

  6. Estimation of age in the living: in matters civil and criminal.

    Science.gov (United States)

    Aggrawal, Anil

    2009-05-11

    Estimation of age is one of the main tasks of a forensic practitioner, especially in third world countries, where many births take place in rural settings without the benefit of the expert supervision of a trained obstetrician. Such births are poorly recorded or more often not recorded at all in terms of exact dates. In many other cases, records are fraudulently falsified for some gain, e.g. to get government jobs or pensions. Developed countries, where ordinarily the birth records are meticulously maintained, are not immune to this problem either. Estimation of the age of living individuals may be needed here for refugees or other persons who arrive without acceptable identification papers. A wide variety of methods are used by the forensic clinician to assess the age of the individual in such cases. This paper discusses and evaluates the most common methods used in India, although the methods can be effectively utilized by medico-legal professionals anywhere in the world.

  7. Magnetic force microscopy reveals meta-stable magnetic domain states that prevent reliable absolute palaeointensity experiments

    NARCIS (Netherlands)

    de Groot, Lennart; Fabian, Karl; Bakelaar, Iman A.; Dekkers, Mark J.

    2014-01-01

    Obtaining reliable estimates of the absolute palaeointensity of the Earth's magnetic field is notoriously difficult. The heating of samples in most methods induces magnetic alteration-a process that is still poorly understood, but prevents obtaining correct field values. Here we show induced changes

  8. Absolute Summ

    Science.gov (United States)

    Phillips, Alfred, Jr.

    Summ means the entirety of the multiverse. It seems clear, from the inflation theories of A. Guth and others, that the creation of many universes is plausible. We argue that Absolute cosmological ideas, not unlike those of I. Newton, may be consistent with dynamic multiverse creations. As suggested in W. Heisenberg's uncertainty principle, and with the Anthropic Principle defended by S. Hawking, et al., human consciousness, buttressed by findings of neuroscience, may have to be considered in our models. Predictability, as A. Einstein realized with Invariants and General Relativity, may be required for new ideas to be part of physics. We present here a two postulate model geared to an Absolute Summ. The seedbed of this work is part of Akhnaton's philosophy (see S. Freud, Moses and Monotheism). Most important, however, is that the structure of human consciousness, manifest in Kenya's Rift Valley 200,000 years ago as Homo sapiens, who were the culmination of the six million year co-creation process of Hominins and Nature in Africa, allows us to do the physics that we do. .

  9. Dental age estimation from the developmental stage of the third molars in western Chinese population.

    Science.gov (United States)

    Li, Guo; Ren, Jiayin; Zhao, Shuping; Liu, Yuanyuan; Li, Na; Wu, Wanhong; Yuan, Shanshan; Wang, Hu

    2012-06-10

    The purpose of this study is to provide reference data about estimating dental age from third molars of the western Chinese population for comparing with other populations and being applied to the age estimation of western Chinese juveniles and adolescents. A total of 2078 digital panoramic radiographs of 989 male and 1089 female Chinese subjects aged between 5 and 23 years were examined. The mineralization status of the third molars was assessed using the formation stages described by Demirjian et al. with two modifications. The results showed that the development of third molars in the western Chinese population was likely to begin at age 5 in both males and females. The third molars 28 and 48 showed significantly higher frequency in females than in males. The third molars 18 in the stage 1, 38 in the stages 1, A and G, and 48 in the stage H showed significantly older average age in females than in males. The Demirjian's stages C and D could be used as a reference stage to determine dichotomously whether a western Chinese is more likely to be under or above age 14 or 16, respectively. This study provided reference data for the age estimation of western Chinese juveniles and adolescents by the mineralization stages of the third molar. Apart from forensic age determination in living subjects, the presented reference data can also be used for age estimations of unidentified corpses and skeletons. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  10. The web-based ASSO-food frequency questionnaire for adolescents: relative and absolute reproducibility assessment.

    Science.gov (United States)

    Filippi, Anna Rita; Amodio, Emanuele; Napoli, Giuseppe; Breda, João; Bianco, Antonino; Jemni, Monèm; Censi, Laura; Mammina, Caterina; Tabacchi, Garden

    2014-12-17

    A new food frequency questionnaire (FFQ) has been recently developed within the Italian Adolescents and Surveillance System for the Obesity prevention (ASSO) Project; it was found to be appropriate for ranking adolescents in food and nutrient levels of intake. The aim of this study was to assess the relative and absolute reproducibility of the ASSO-FFQ for 24 food groups, energy and 52 nutrients. A test-retest study was performed on two ASSO-FFQs administered one month apart of each other to 185 adolescents, aged 14-17 and attending secondary schools in Palermo (Italy). Wilcoxon test assessed differences in median daily intakes between the two FFQs. Agreement was evaluated by quintiles comparison and weighted kappa. Intraclass Correlation Coefficients (ICC) and Bland-Altman method assessed the relative and absolute reliability respectively. Significant difference (p food, water, soft drinks, carbohydrates and sugar. The subjects classified into the same or adjacent quintiles for food groups ranged from 62% (white bread) to 91% (soft drinks); for energy and nutrients from 64% (polyunsaturated fatty acids) to 90% (ethanol). Mean values of weighted kappa were 0.47 and 0.48, respectively for food groups and nutrients. Fair to good ICC values (>0.40) were assessed for thirteen food groups, energy and forty-three nutrients. Limits of Agreement were narrow for almost all food groups and all nutrients. The ASSO-FFQ is a reliable instrument for estimating food groups, energy and nutrients intake in adolescents.

  11. Weight Estimation Tool for Children Aged 6 to 59 Months in Limited-Resource Settings.

    Science.gov (United States)

    Ralston, Mark E; Myatt, Mark A

    2016-01-01

    A simple, reliable anthropometric tool for rapid estimation of weight in children would be useful in limited-resource settings where current weight estimation tools are not uniformly reliable, nearly all global under-five mortality occurs, severe acute malnutrition is a significant contributor in approximately one-third of under-five mortality, and a weight scale may not be immediately available in emergencies to first-response providers. To determine the accuracy and precision of mid-upper arm circumference (MUAC) and height as weight estimation tools in children under five years of age in low-to-middle income countries. This was a retrospective observational study. Data were collected in 560 nutritional surveys during 1992-2006 using a modified Expanded Program of Immunization two-stage cluster sample design. Locations with high prevalence of acute and chronic malnutrition. A total of 453,990 children met inclusion criteria (age 6-59 months; weight ≤ 25 kg; MUAC 80-200 mm) and exclusion criteria (bilateral pitting edema; biologically implausible weight-for-height z-score (WHZ), weight-for-age z-score (WAZ), and height-for-age z-score (HAZ) values). Weight was estimated using Broselow Tape, Hong Kong formula, and database MUAC alone, height alone, and height and MUAC combined. Mean percentage difference between true and estimated weight, proportion of estimates accurate to within ± 25% and ± 10% of true weight, weighted Kappa statistic, and Bland-Altman bias were reported as measures of tool accuracy. Standard deviation of mean percentage difference and Bland-Altman 95% limits of agreement were reported as measures of tool precision. Database height was a more accurate and precise predictor of weight compared to Broselow Tape 2007 [B], Broselow Tape 2011 [A], and MUAC. Mean percentage difference between true and estimated weight was +0.49% (SD = 10.33%); proportion of estimates accurate to within ± 25% of true weight was 97.36% (95% CI 97.40%, 97.46%); and

  12. Lifetime estimation of zirconia ceramics by linear ageing kinetics

    International Nuclear Information System (INIS)

    Zhang, Fei; Inokoshi, Masanao; Vanmeensel, Kim; Van Meerbeek, Bart; Naert, Ignace; Vleugels, Jef

    2015-01-01

    Up to now, the ageing kinetics of zirconia ceramics were mainly derived from the sigmoidal evolution of the surface phase transformation as a function of time, as quantified by means of X-ray diffraction (XRD). However, the transformation propagation into the material should be better to monitor the ageing kinetics. In this work, μ-Raman spectroscopy was used to quantitatively measure the transformation profiles in depth as a function of ageing time at 160 °C, 140 °C, 134 °C and 110 °C. A linear relationship between the transformed depth and the ageing time was observed for all investigated yttria stabilized tetragonal zirconia polycrystals (3Y-TZP). Furthermore, the μ-Raman investigation of residual stresses in the subsurface of aged 3Y-TZPs showed that the highest tensile stress was located just ahead of the transformation front, indicating the key responsibility of stress accumulation for transformation front propagating into the material. Moreover, the linear kinetics of the transformation propagation were more accurate to calculate the apparent activation energy of the ageing process and allowed a more straightforward estimation of the lifetime of 3Y-TZP at body temperature, as compared to the conventional ageing kinetic parameters obtained from the surface transformation analysis by XRD

  13. Normative perceptual estimates for 91 healthy subjects age 60-75

    DEFF Research Database (Denmark)

    Wilms, Inge Linda; Nielsen, Simon

    2014-01-01

    Visual perception serves as the basis for much of the higher level cognitive processing as well as human activity in general. Here we present normative estimates for the following components of visual perception: the visual perceptual threshold, the visual short-term memory capacity and the visual...... perceptual encoding/decoding speed (processing speed) of visual short-term memory based on an assessment of 91 healthy subjects aged 60-75. The estimates are presented at total sample level as well as at gender level. The estimates were modelled from input from a whole-report assessment based on A Theory...... speed of Visual Short-term Memory (VTSM) but not the capacity of VSTM nor the visual threshold. The estimates will be useful for future studies into the effects of various types of intervention and training on cognition in general and visual attention in particular....

  14. Absolute flux scale for radioastronomy

    International Nuclear Information System (INIS)

    Ivanov, V.P.; Stankevich, K.S.

    1986-01-01

    The authors propose and provide support for a new absolute flux scale for radio astronomy, which is not encumbered with the inadequacies of the previous scales. In constructing it the method of relative spectra was used (a powerful tool for choosing reference spectra). A review is given of previous flux scales. The authors compare the AIS scale with the scale they propose. Both scales are based on absolute measurements by the ''artificial moon'' method, and they are practically coincident in the range from 0.96 to 6 GHz. At frequencies above 6 GHz, 0.96 GHz, the AIS scale is overestimated because of incorrect extrapolation of the spectra of the primary and secondary standards. The major results which have emerged from this review of absolute scales in radio astronomy are summarized

  15. K-Ar age estimate for the KBS Tuff, East Turkana, Kenya

    International Nuclear Information System (INIS)

    McDougall, I.; Maier, R.; Sutherland-Hawkes, P.; Gleadow, A.J.W.

    1980-01-01

    Stone tools and numerous vertebrate fossils including hominids, have been found in close stratigraphic proximity to the KBS Tuff, whose age has been the subject of much debate. Concordant K-Ar ages, averaging 1.89 +- 0.01 Myr, are reported on anorthoclase phenocrysts from 13 pumice clasts collected from within the KBS Tuff or its correlatives. It is believed that this age is the best estimate currently available for the time of formation of this important marker horizon within the East Turkana Basin. (author)

  16. An Improved Method for Estimating Water-Mass Ventilation Age from Radiocarbon Measurements

    Science.gov (United States)

    Devries, T. J.; Primeau, F. W.

    2009-12-01

    Paleoceanographic data can help to constrain the state of the past ocean circulation. One critical quantity that can be constrained by paleoceanographic data is the ventilation age, which measures the vigor of the ocean circulation. Paleoceanographers often use radiocarbon data to estimate paleo-ventilation ages by calculating either the benthic-planktonic (B-P) age difference, or the so-called “projection” age. However, recent studies have shown that neither of these calculations yield correct estimates of ventilation age, due to fluctuations in atmospheric radiocarbon content and mixing processes in the ocean. Here we propose a new method for more accurately inferring paleo-ventilation ages based on radiocarbon data. Our method makes use of a model that uses parameterized transfer functions to simulate the effects of circulation and mixing in the ocean. We show how this model can be used in a Bayesian framework to infer a ventilation age from a paired radiocarbon- and calendar-age measurement. The Bayesian framework allows us to quantify the uncertainty in the inferred ventilation age due to uncertainty in the data, as well as uncertainty in the assumptions made in the model itself. We applied this framework to previously published radiocarbon data from the deep North Pacific spanning 10 000 to 20 000 years before present. Ventilation ages inferred using our method are significantly different from the B-P ages or projection ages calculated from the same data. Furthermore, our analysis suggests that the uncertainty of the ventilation ages is on the order of 400-500 years, and that the main sources of uncertainty are uncertainty in the age of surface source waters and in the true calendar age of the radiocarbon data. Our results do not show a clear change in the ventilation age of deep North Pacific waters during the last deglaciation.

  17. Clonal diversity and estimation of relative clone age: application to agrobiodiversity of yam (Dioscorea rotundata).

    Science.gov (United States)

    Scarcelli, Nora; Couderc, Marie; Baco, Mohamed N; Egah, Janvier; Vigouroux, Yves

    2013-11-13

    Clonal propagation is a particular reproductive system found in both the plant and animal kingdoms, from human parasites to clonally propagated crops. Clonal diversity provides information about plant and animal evolutionary history, i.e. how clones spread, or the age of a particular clone. In plants, this could provide valuable information about agrobiodiversity dynamics and more broadly about the evolutionary history of a particular crop. We studied the evolutionary history of yam, Dioscorea rotundata. In Africa, Yam is cultivated by tuber clonal propagation. We used 12 microsatellite markers to identify intra-clonal diversity in yam varieties. We then used this diversity to assess the relative ages of clones. Using simulations, we assessed how Approximate Bayesian Computation could use clonal diversity to estimate the age of a clone depending on the size of the sample, the number of independent samples and the number of markers. We then applied this approach to our particular dataset and showed that the relative ages of varieties could be estimated, and that each variety could be ranked by age. We give a first estimation of clone age in an approximate Bayesian framework. However the precise estimation of clone age depends on the precision of the mutation rate. We provide useful information on agrobiodiversity dynamics and suggest recurrent creation of varietal diversity in a clonally propagated crop.

  18. Comparative study of age estimation using dentinal translucency by digital and conventional methods

    Science.gov (United States)

    Bommannavar, Sushma; Kulkarni, Meena

    2015-01-01

    Introduction: Estimating age using the dentition plays a significant role in identification of the individual in forensic cases. Teeth are one of the most durable and strongest structures in the human body. The morphology and arrangement of teeth vary from person-to-person and is unique to an individual as are the fingerprints. Therefore, the use of dentition is the method of choice in the identification of the unknown. Root dentin translucency is considered to be one of the best parameters for dental age estimation. Traditionally, root dentin translucency was measured using calipers. Recently, the use of custom built software programs have been proposed for the same. Objectives: The present study describes a method to measure root dentin translucency on sectioned teeth using a custom built software program Adobe Photoshop 7.0 version (Adobe system Inc, Mountain View California). Materials and Methods: A total of 50 single rooted teeth were sectioned longitudinally to derive a 0.25 mm uniform thickness and the root dentin translucency was measured using digital and caliper methods and compared. The Gustafson's morphohistologic approach is used in this study. Results: Correlation coefficients of translucency measurements to age were statistically significant for both the methods (P < 0.125) and linear regression equations derived from both methods revealed better ability of the digital method to assess age. Conclusion: The custom built software program used in the present study is commercially available and widely used image editing software. Furthermore, this method is easy to use and less time consuming. The measurements obtained using this method are more precise and thus help in more accurate age estimation. Considering these benefits, the present study recommends the use of digital method to assess translucency for age estimation. PMID:25709325

  19. Do We Really Have an Age/H_0 Conflict?

    Science.gov (United States)

    Baum, W. A.

    1997-12-01

    Two independent methods for estimating the age of the universe can both be linked to the absolute magnitudes of the RR Lyrae stars, one based on stellar evolution in globular clusters and the other based on the Hubble Constant derived from globular clusters as distance indicators. The latter has recently been extracted from HST-WFPC2 data for globular clusters in the Coma Cluster galaxy IC 4051 (Baum et al. 1997, AJ, 113, 1483). If RR Lyrae stars are brighter than we have previously thought, the stellar-evolution age estimate is shortened whereas the Hubble age is increased, so we can ask a very simple question: For what RR Lyrae magnitude zero point would the stellar-evolution age coincide with the Hubble age, and is it a reasonable value? Allowing 1 Gyr for globular clusters to have formed, and assuming a classical Einstein-deSitter universe with Lambda = 0, I find the two ages to coincide if M_V(RR) ~ 0.16[Fe/H] + 0.46, which (among other things) puts the Large Magellanic Cloud at (m-M) = 18.78 +/- 0.17 mag. The implied age of the universe is 11.0 +/- 1.4 Gyr, and the corresponding H_0 = 59 +/- 8 km/s per Mpc.

  20. Estimation of Aging Effects on LOHS for CANDU-6

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Yong Ki; Moon, Bok Ja; Kim, Seoung Rae [Nuclear Engineering Service and Solution Co. Ltd., Daejeon (Korea, Republic of)

    2014-05-15

    To evaluate the Wolsong Unit 1's capacity to respond to large-scale natural disaster exceeding design, the loss of heat sink(LOHS) accident accompanied by loss of all electric power is simulated as a beyond design basis accident. This analysis is considered the aging effects of plant as the consequences of LOHS accident. Various components of primary heat transport system(PHTS) get aged and some of the important aging effects of CANDU reactor are pressure tube(PT) diametral creep, steam generator(SG) U-tube fouling, increased feeder roughness, and feeder orifice degradation. These effects result in higher inlet header temperatures, reduced flows in some fuel channels, and higher void fraction in fuel channel outlets. Fresh and aged models are established for the analysis where fresh model is the circuit model simulating the conditions at retubing and aged model corresponds to the model reflecting the aged condition at 11 EFPY after retubing. CATHENA computer code[1] is used for the analysis of the system behavior under LOHS condition. The LOHS accident is analyzed for fresh and aged models using CATHENA thermal hydraulic computer code. The decay heat removal is one of the most important factors for mitigation of this accident. The major aging effect on decay heat removal is the reduction of heat transfer efficiency by steam generator. Thus, the channel failure time cannot be conservatively estimated if aged model is applied for the analysis of this accident.

  1. Calliphora vicina (Diptera: Calliphoridae) pupae: a timeline of external morphological development and a new age and PMI estimation tool.

    Science.gov (United States)

    Brown, Katherine; Thorne, Alan; Harvey, Michelle

    2015-07-01

    The minimum postmortem interval (PMI(min)) is commonly estimated using calliphorid larvae, for which there are established age estimation methods based on morphological and development data. Despite the increased duration and sedentary nature of the pupal stage of the blowfly, morphological age estimation methods are poorly documented and infrequently used for PMI determination. The aim of this study was to develop a timeline of metamorphosis, focusing on the development of external morphology (within the puparium), to provide a means of age and PMI estimation for Calliphora vicina (Rob-Desvoidy) pupae. Under controlled conditions, 1,494 pupae were reared and sampled at regular time intervals. After puparium removal, observations of 23 external metamorphic developments were correlated to age in accumulated degree hours (ADH). Two age estimation methods were developed based on (1) the combination of possible age ranges observed for each characteristic and (2) regression analyses to generate age estimation equations employing all 23 characteristics observed and a subset of ten characteristics most significantly correlated with age. Blind sample analysis indicated that, using the combination of both methods, pupal age could be estimated to within ±500 ADH with 95% reliability.

  2. Maintenance Management Support Systems for component aging estimation at nuclear power plants

    International Nuclear Information System (INIS)

    Shimizu, Shunichi; Ando, Yasumasa; Morioka, Toshihiko; Okuzumi, Naoaki

    1991-01-01

    Maintenance Management Support Systems (MMSSs) for nuclear power plants have been developed using component aging estimation methods and decision tree analysis for maintenance planning. The former evaluates actual component reliability through statistical analysis on field maintenance data. The latter provides preventive maintenance (PM) planning guidance using heuristic expert knowledge and estimated reliability parameters. The following aspects have been investigated: (1) A systematic and effective method of managing components/parts design information and field maintenance data (2) A method for estimating component aging based on a statistical analysis of field maintenance data (3) A method for providing PM planning guidance using estimated component reliability/performance parameters and decision tree analysis. Based on these investigations, two MMSSs were developed. One deals with 'general maintenance data', which are common to all component types and are amenable to common data handling. The other system deals with 'specific maintenance data', which are specific to an individual component type. Both systems provide PM planning guidance for PM cycles propriety and the PM work priority. The function of these systems were verified using simulated maintenance data. (author)

  3. Heterogeneous Rates of Molecular Evolution and Diversification Could Explain the Triassic Age Estimate for Angiosperms.

    Science.gov (United States)

    Beaulieu, Jeremy M; O'Meara, Brian C; Crane, Peter; Donoghue, Michael J

    2015-09-01

    Dating analyses based on molecular data imply that crown angiosperms existed in the Triassic, long before their undisputed appearance in the fossil record in the Early Cretaceous. Following a re-analysis of the age of angiosperms using updated sequences and fossil calibrations, we use a series of simulations to explore the possibility that the older age estimates are a consequence of (i) major shifts in the rate of sequence evolution near the base of the angiosperms and/or (ii) the representative taxon sampling strategy employed in such studies. We show that both of these factors do tend to yield substantially older age estimates. These analyses do not prove that younger age estimates based on the fossil record are correct, but they do suggest caution in accepting the older age estimates obtained using current relaxed-clock methods. Although we have focused here on the angiosperms, we suspect that these results will shed light on dating discrepancies in other major clades. ©The Author(s) 2015. Published by Oxford University Press, on behalf of the Society of Systematic Biologists. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  4. Estimating the Spatial Distribution of Groundwater Age Using Synoptic Surveys of Environmental Tracers in Streams

    Science.gov (United States)

    Gardner, W. P.

    2017-12-01

    A model which simulates tracer concentration in surface water as a function the age distribution of groundwater discharge is used to characterize groundwater flow systems at a variety of spatial scales. We develop the theory behind the model and demonstrate its application in several groundwater systems of local to regional scale. A 1-D stream transport model, which includes: advection, dispersion, gas exchange, first-order decay and groundwater inflow is coupled a lumped parameter model that calculates the concentration of environmental tracers in discharging groundwater as a function of the groundwater residence time distribution. The lumped parameters, which describe the residence time distribution, are allowed to vary spatially, and multiple environmental tracers can be simulated. This model allows us to calculate the longitudinal profile of tracer concentration in streams as a function of the spatially variable groundwater age distribution. By fitting model results to observations of stream chemistry and discharge, we can then estimate the spatial distribution of groundwater age. The volume of groundwater discharge to streams can be estimated using a subset of environmental tracers, applied tracers, synoptic stream gauging or other methods, and the age of groundwater then estimated using the previously calculated groundwater discharge and observed environmental tracer concentrations. Synoptic surveys of SF6, CFC's, 3H and 222Rn, along with measured stream discharge are used to estimate the groundwater inflow distribution and mean age for regional scale surveys of the Berland River in west-central Alberta. We find that groundwater entering the Berland has observable age, and that the age estimated using our stream survey is of similar order to limited samples from groundwater wells in the region. Our results show that the stream can be used as an easily accessible location to constrain the regional scale spatial distribution of groundwater age.

  5. Estimating the brain pathological age of Alzheimer’s disease patients from MR image data based on the separability distance criterion

    Science.gov (United States)

    Li, Yongming; Li, Fan; Wang, Pin; Zhu, Xueru; Liu, Shujun; Qiu, Mingguo; Zhang, Jingna; Zeng, Xiaoping

    2016-10-01

    Traditional age estimation methods are based on the same idea that uses the real age as the training label. However, these methods ignore that there is a deviation between the real age and the brain age due to accelerated brain aging. This paper considers this deviation and searches for it by maximizing the separability distance value rather than by minimizing the difference between the estimated brain age and the real age. Firstly, set the search range of the deviation as the deviation candidates according to prior knowledge. Secondly, use the support vector regression (SVR) as the age estimation model to minimize the difference between the estimated age and the real age plus deviation rather than the real age itself. Thirdly, design the fitness function based on the separability distance criterion. Fourthly, conduct age estimation on the validation dataset using the trained age estimation model, put the estimated age into the fitness function, and obtain the fitness value of the deviation candidate. Fifthly, repeat the iteration until all the deviation candidates are involved and get the optimal deviation with maximum fitness values. The real age plus the optimal deviation is taken as the brain pathological age. The experimental results showed that the separability was apparently improved. For normal control-Alzheimer’s disease (NC-AD), normal control-mild cognition impairment (NC-MCI), and MCI-AD, the average improvements were 0.178 (35.11%), 0.033 (14.47%), and 0.017 (39.53%), respectively. For NC-MCI-AD, the average improvement was 0.2287 (64.22%). The estimated brain pathological age could be not only more helpful to the classification of AD but also more precisely reflect accelerated brain aging. In conclusion, this paper offers a new method for brain age estimation that can distinguish different states of AD and can better reflect the extent of accelerated aging.

  6. Achilles: A Homeric hero enamoured with the absolute.

    Science.gov (United States)

    Evzonas, Nicolas

    2017-07-21

    This article explores through a psychoanalytical lens the character of Achilles in Homer's Iliad, the matrix behind the Western conception of heroism. The contribution reveals the psychological link binding the words and acts of the most valiant of warriors in Antiquity, which is situated in myth and termed "the Eros of the absolute." The paroxystic ideality underlying the aforementioned myth, which is rooted in the anthropological need to believe, is at the origin of Achilles' legendary μῆνις, that is, the flood of rage triggered by contests for supremacy, aggravated by the loss of his war comrade, aroused by the drama of aging and death, and then transfigured through song and memory. The main claim of the author is that Iliad, despite its seeming lack of attention to interiority, is launched by the archetypal emotion of wrath and owes its appeal to its hero's embrace of heroic idealism in an excessive, radical and absolute way that results in a captivating narcissism and sadomasochistic antithesis of ideality. This argument leads to the conclusion that Homer is the Father of the "primitive horde" of affects. Copyright © 2017 Institute of Psychoanalysis.

  7. Radiological age estimation: based on third molar mineralization and eruption in Turkish children and young adults.

    Science.gov (United States)

    Karadayi, Beytullah; Kaya, Ahsen; Kolusayın, Melek Ozlem; Karadayi, Sükriye; Afsin, Hüseyin; Ozaslan, Abdi

    2012-11-01

    Radiographic evaluation of mineralization and eruption stages of third molars using dental panoramic radiographies can be an efficient tool for chronological age estimation in both forensic sciences and legal medicine. The third molar tooth is utilized for dental age estimation about the age span of 15-23 years because it represents the only tooth still in development. The aim of this study is to obtain and analyze data regarding third molar development and eruption in Turkish population for dental age estimation. A total of 744 dental panoramic radiographies of 394 female and 350 male subjects aged between 8 and 22 years were examined. Third molar development was determined according to the Nolla classification system, and eruption was assessed relative to the alveolar bone level. Mandibular and maxillary third molars were generally found at similar stages of development on both sides. Nolla stage 6 (completed crown calcification) was reached at around the age of 15 in both maxillary and mandibular third molars in both sexes. Alveolar emergence was at around the age of 16 in males and around age of 17 in females. Although third molars' eruption shows greater variability than development of third molars, data which were obtained from this study about eruption of these teeth can be supportive to development data for age estimation.

  8. Forensic individual age estimation with DNA: From initial approaches to methylation tests.

    Science.gov (United States)

    Freire-Aradas, A; Phillips, C; Lareu, M V

    2017-07-01

    Individual age estimation is a key factor in forensic science analysis that can provide very useful information applicable to criminal, legal, and anthropological investigations. Forensic age inference was initially based on morphological inspection or radiography and only later began to adopt molecular approaches. However, a lack of accuracy or technical problems hampered the introduction of these DNA-based methodologies in casework analysis. A turning point occurred when the epigenetic signature of DNA methylation was observed to gradually change during an individual´s lifespan. In the last four years, the number of publications reporting DNA methylation age-correlated changes has gradually risen and the forensic community now has a range of age methylation tests applicable to forensic casework. Most forensic age predictor models have been developed based on blood DNA samples, but additional tissues are now also being explored. This review assesses the most widely adopted genes harboring methylation sites, detection technologies, statistical age-predictive analyses, and potential causes of variation in age estimates. Despite the need for further work to improve predictive accuracy and establishing a broader range of tissues for which tests can analyze the most appropriate methylation sites, several forensic age predictors have now been reported that provide consistency in their prediction accuracies (predictive error of ±4 years); this makes them compelling tools with the potential to contribute key information to help guide criminal investigations. Copyright © 2017 Central Police University.

  9. The biochemical estimation of age in Euphausiids: Laboratory calibration and field comparisons

    Science.gov (United States)

    Harvey, H. R.; Ju, Se-J.; Son, S.-K.; Feinberg, L. R.; Shaw, C. T.; Peterson, W. T.

    2010-04-01

    Euphausiids play a key role in many marine ecosystems as a link between primary producers and top predators. Understanding their demographic (i.e. age) structure is an essential tool to assess growth and recruitment as well as to determine how changes in environmental conditions might alter their condition and distribution. Age determination of crustaceans cannot be accomplished using traditional approaches, and here we evaluate the potential for biochemical products of tissue metabolism (termed lipofuscins) to determine the demographic structure of euphausiids in field collections . Lipofuscin was extracted from krill neural tissues (eye and eye-stalk), quantified using fluorescent intensity and normalized to tissue protein content to allow comparisons across animal sizes. Multiple fluorescent components from krill were observed, with the major product having a maximum fluorescence at excitation of 355 nm and emission of 510 nm. Needed age calibration of lipofuscin accumulation in Euphausia pacifica was accomplished using known-age individuals hatched and reared in the laboratory for over one year. Lipofuscin content extracted from neural tissues of laboratory-reared animals was highly correlated with the chronological age of animals ( r=0.87). Calibrated with laboratory lipofuscin accumulation rates, field-collected sub-adult and adult E. pacifica in the Northeast Pacific were estimated to be older than 100 days and younger than 1year. Comparative data for the Antarctic krill, E. superba showed much higher lipofuscin values suggesting a much longer lifespan than the more temperate species, E. pacifica. These regional comparisons suggest that biochemical indices allow a practical approach to estimate population age structure of diverse populations, and combined with other measurements can provide estimates of vital rates (i.e. longevity, mortality, growth) for krill populations in dynamic environments.

  10. Systematics of Absolute Gamma Ray Transition Probabilities in Deformed Odd-A Nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Malmskog, S G

    1965-11-15

    All known experimentally determined absolute gamma ray transition probabilities between different intrinsic states of deformed odd-A nuclei in the rare earth, region (153 < A < 181) and in the actinide region (A {>=} 227) are compared with transition probabilities (Weisskopf and Nilsson estimate). Systematic deviations from the theoretical values are found. Possible explanations for these deviations are given. This discussion includes Coriolis coupling, {delta}K ={+-}2 band-mixing effects and pairing interaction.

  11. A case-control study to assess the impact of mammographic density on breast cancer risk in women aged 40-49 at intermediate familial risk.

    Science.gov (United States)

    Assi, Valentina; Massat, Nathalie J; Thomas, Susan; MacKay, James; Warwick, Jane; Kataoka, Masako; Warsi, Iqbal; Brentnall, Adam; Warren, Ruth; Duffy, Stephen W

    2015-05-15

    Mammographic density is a strong risk factor for breast cancer, but its potential application in risk management is not clear, partly due to uncertainties about its interaction with other breast cancer risk factors. We aimed to quantify the impact of mammographic density on breast cancer risk in women aged 40-49 at intermediate familial risk of breast cancer (average lifetime risk of 23%), in particular in premenopausal women, and to investigate its relationship with other breast cancer risk factors in this population. We present the results from a case-control study nested with the FH01 cohort study of 6,710 women mostly aged 40-49 at intermediate familial risk of breast cancer. One hundred and three cases of breast cancer were age-matched to one or two controls. Density was measured by semiautomated interactive thresholding. Absolute density, but not percent density, was a significant risk factor for breast cancer in this population after adjusting for area of nondense tissue (OR per 10 cm(2) = 1.07, 95% CI 1.00-1.15, p = 0.04). The effect was stronger in premenopausal women, who made up the majority of the study population. Absolute density remained a significant predictor of breast cancer risk after adjusting for age at menarche, age at first live birth, parity, past or present hormone replacement therapy, and the Tyrer-Cuzick 10-year relative risk estimate of breast cancer. Absolute density can improve breast cancer risk stratification and delineation of high-risk groups alongside the Tyrer-Cuzick 10-year relative risk estimate. © 2014 UICC.

  12. Globular Clusters: Absolute Proper Motions and Galactic Orbits

    Science.gov (United States)

    Chemel, A. A.; Glushkova, E. V.; Dambis, A. K.; Rastorguev, A. S.; Yalyalieva, L. N.; Klinichev, A. D.

    2018-04-01

    We cross-match objects from several different astronomical catalogs to determine the absolute proper motions of stars within the 30-arcmin radius fields of 115 Milky-Way globular clusters with the accuracy of 1-2 mas yr-1. The proper motions are based on positional data recovered from the USNO-B1, 2MASS, URAT1, ALLWISE, UCAC5, and Gaia DR1 surveys with up to ten positions spanning an epoch difference of up to about 65 years, and reduced to Gaia DR1 TGAS frame using UCAC5 as the reference catalog. Cluster members are photometrically identified by selecting horizontal- and red-giant branch stars on color-magnitude diagrams, and the mean absolute proper motions of the clusters with a typical formal error of about 0.4 mas yr-1 are computed by averaging the proper motions of selected members. The inferred absolute proper motions of clusters are combined with available radial-velocity data and heliocentric distance estimates to compute the cluster orbits in terms of the Galactic potential models based on Miyamoto and Nagai disk, Hernquist spheroid, and modified isothermal dark-matter halo (axisymmetric model without a bar) and the same model + rotating Ferre's bar (non-axisymmetric). Five distant clusters have higher-than-escape velocities, most likely due to large errors of computed transversal velocities, whereas the computed orbits of all other clusters remain bound to the Galaxy. Unlike previously published results, we find the bar to affect substantially the orbits of most of the clusters, even those at large Galactocentric distances, bringing appreciable chaotization, especially in the portions of the orbits close to the Galactic center, and stretching out the orbits of some of the thick-disk clusters.

  13. Invariant and Absolute Invariant Means of Double Sequences

    Directory of Open Access Journals (Sweden)

    Abdullah Alotaibi

    2012-01-01

    Full Text Available We examine some properties of the invariant mean, define the concepts of strong σ-convergence and absolute σ-convergence for double sequences, and determine the associated sublinear functionals. We also define the absolute invariant mean through which the space of absolutely σ-convergent double sequences is characterized.

  14. In vitro absolute metabolic quantification by magnetic resonance spectroscopy; Quantificacao metabolica absoluta in vitro por espectroscopia de ressonancia magnetica

    Energy Technology Data Exchange (ETDEWEB)

    Barreto, Felipe R.; Salmon, Carlos E.G. [Universidade de Sao Paulo (USP), Ribeirao Preto, SP (Brazil). Faculdade de Filosofia, Ciencias e Letras. Dept. de Fisica e Matematica], e-mail: garrido@ffclrp.usp.br

    2010-03-15

    In this project we estimated characteristic nuclear relaxation times (T1 and T2) from {sup 1}H in vitro of water and the following human brain metabolites: N-Acetyl-Aspartate (NAA), Choline (Cho), Creatine (Cr) and Myo-Inositol (M-Ins) using nuclear magnetic resonance spectroscopy, aiming at relaxation effects correction for absolute quantification. Phantoms with 300 mL of a standard solution with a metabolite were used for spectra acquisition. Variable eco time sequences were used to determinate T2 while variable repetition or inversion time was used for T1 determination. Spectra processing was done with MRUI and LCModel software. Origin 8.0 was used for data fitting. The following T1/T2 values (ms) were the best estimated according to calculated absolute concentration analyses: (4061/934) for water, (1800/830) for NAA, (2316/717) for Cr, (2356/1095) for Cho and (1537/531) for M-Ins. With MRUI better results were obtained in T1 and T2 determination for relaxation effects correction in the absolute quantification process. (author)

  15. Age validation and growth of yolked larvae of Patagonotothen tessellata (Richardson, 1845 (Pisces: Nototheniidae from the rocky littoral of the Beagle Channel, Argentina

    Directory of Open Access Journals (Sweden)

    Gustavo Alfredo Rae

    1999-12-01

    Full Text Available Age and growth estimation of Patagonotothen tessellata larvae over the endogenous period was estimated by examining their otolith microstructure and the associated increment deposition rate. Analyzed specimens were incubated from egg-masses collected in Lapataia Bay, Beagle Channel, Argentina. Validation was performed by monitoring reared larvae of known ages. Actual age and increment count were regressed suggesting a daily deposition of one ring in the otolith, which began at hatching time and continued until larvae reached sixteen days old (time of massive mortality. Mean lengths at each age were estimated using Richards´ growth function; their constant (m attained a value close to zero indicating that the data fitted to the von Bertalanffy model. Absolute growth rate was 0.55 mm*d-1of total length at hatching, dropped near zero on the fifth day after hatching and afterwards, there was no growth. Yolk absorption rate (expressed as a ratio between minor axis/major axis of the vitelline-sac showed a similar variation as that observed in absolute growth rate during the endogenous period. The total yolk absorption took five days in the unfed larvae group and seven days in the fed larvae group. The rapid absorption of the yolk and the observed growth pattern suggest that Patagonotothen tessellata larvae have a short endogenous period, reaching the state of first food uptake five days after hatching.

  16. Bone age estimation and prediction of final height in patients with {beta}-thalassaemia major: a comparison between the two most common methods

    Energy Technology Data Exchange (ETDEWEB)

    Christoforidis, Athanasios; Katzos, George; Athanassiou-Metaxa, Miranda [Aristotle University of Thessaloniki, 1st Paediatric Department, Thessaloniki (Greece); Badouraki, Maria [Ippokratio Hospital, Paediatric Radiology Department, Thessaloniki (Greece)

    2007-12-15

    Thalassaemic patients are in need of frequent assessment of bone age because of growth failure and pubertal disorders. To compare the ''rapid'' Greulich and Pyle (G and P) method with the third edition of the Tanner and Whitehouse (TW3) method for determining skeletal maturity and predicting final height in thalassaemic patients. A total of 191 radiographs from 58 patients (28 male, 30 female) were retrospectively evaluated by two investigators, one for each method. In 47 radiographs from 15 patients having attained their adult height, predicted final height was calculated according to each method. The mean bone ages determined by both the G and P and TW3 methods were lower than mean chronological age, although the differences were not statistically significant (10.04 {+-} 3.69 years and 9.98 {+-} 3.39 years vs. 10.78 {+-} 3.96 years, respectively). Both methods had a tendency to over-estimate final height. Overall, the TW3 method seemed to be more accurate than the G and P method (mean absolute error 3.21 {+-} 2.51 years vs. 3.99 {+-} 2.99 years, respectively, P=0.048). The same method should be used when serial assessments are performed, as both methods provide similarly reliable, although not equivalent, results. The TW3 height prediction method seemed to be more accurate in patients with {beta}-thalassaemia major than the G and P method, albeit with a large confidence interval. (orig.)

  17. Bone age estimation and prediction of final height in patients with β-thalassaemia major: a comparison between the two most common methods

    International Nuclear Information System (INIS)

    Christoforidis, Athanasios; Katzos, George; Athanassiou-Metaxa, Miranda; Badouraki, Maria

    2007-01-01

    Thalassaemic patients are in need of frequent assessment of bone age because of growth failure and pubertal disorders. To compare the ''rapid'' Greulich and Pyle (G and P) method with the third edition of the Tanner and Whitehouse (TW3) method for determining skeletal maturity and predicting final height in thalassaemic patients. A total of 191 radiographs from 58 patients (28 male, 30 female) were retrospectively evaluated by two investigators, one for each method. In 47 radiographs from 15 patients having attained their adult height, predicted final height was calculated according to each method. The mean bone ages determined by both the G and P and TW3 methods were lower than mean chronological age, although the differences were not statistically significant (10.04 ± 3.69 years and 9.98 ± 3.39 years vs. 10.78 ± 3.96 years, respectively). Both methods had a tendency to over-estimate final height. Overall, the TW3 method seemed to be more accurate than the G and P method (mean absolute error 3.21 ± 2.51 years vs. 3.99 ± 2.99 years, respectively, P=0.048). The same method should be used when serial assessments are performed, as both methods provide similarly reliable, although not equivalent, results. The TW3 height prediction method seemed to be more accurate in patients with β-thalassaemia major than the G and P method, albeit with a large confidence interval. (orig.)

  18. Absolute measurement of a tritium standard

    International Nuclear Information System (INIS)

    Hadzisehovic, M.; Mocilnik, I.; Buraei, K.; Pongrac, S.; Milojevic, A.

    1978-01-01

    For the determination of a tritium absolute activity standard, a method of internal gas counting has been used. The procedure involves water reduction by uranium and zinc further the measurement of the absolute disintegration rate of tritium per unit of the effective volume of the counter by a compensation method. Criteria for the choice of methods and procedures concerning the determination and measurement of gaseous 3 H yield, parameters of gaseous hydrogen, sample mass of HTO and the absolute disintegration rate of tritium are discussed. In order to obtain gaseous sources of 3 H (and 2 H), the same reversible chemical reaction was used, namely, the water - uranium hydride - hydrogen system. This reaction was proved to be quantitative above 500 deg C by measuring the yield of the gas obtained and the absolute activity of an HTO standard. A brief description of the measuring apparatus is given, as well as a critical discussion of the brass counter quality and the possibility of obtaining equal working conditions at the counter ends. (T.G.)

  19. Number 13 / Part I. Music. 7. Grounds of Absolute Pitch Development in Yamaha Music School

    Directory of Open Access Journals (Sweden)

    Iușcă Dorina

    2017-03-01

    Full Text Available Absolute pitch is defined as the ability to identify the pitch class of a certain given sound without the aid of an external reference pitch (Takeuchi & Hulse, 1993; Deutsch, 2002. The incidence of absolute pitch is extremely rare among the general population, respectively 1 in 10.000 people and it depends on testing conditions such as the number of identified sounds, pitch Chroma, pitch height, timbre, register or requested reaction time, and also on subjects musical training commencing and Eastern-Asian origins. The way absolute pitch develops is described by three models: the tone language theory, the early training theory and the genetic theory. The early training theory states that absolute pitch appears due to the beginning of musical lessons during a critical development period situated before the age of 6. The educational implications of this theory are revealed in the principles and activities of Yamaha Music School which employs didactic strategies that naturally develop absolute pitch. Yamaha Music School is the largest private music education system from Japan, established by Torakusu Yamaha in 1954. Up to this day it has extended in 40 countries from Europe, Asia and the American continents, as it has about 710 million students and 30.000 teachers. The present study aims to illustrate a detailed analysis of the way the learning experiences offered by Yamaha School lead to the development of absolute pitch.

  20. Absolute or relative? A comparative analysis of the relationship between poverty and mortality.

    Science.gov (United States)

    Fritzell, Johan; Rehnberg, Johan; Bacchus Hertzman, Jennie; Blomgren, Jenni

    2015-01-01

    We aimed to examine the cross-national and cross-temporal association between poverty and mortality, in particular differentiating the impact of absolute and relative poverty. We employed pooled cross-sectional time series analysis. Our measure of relative poverty was based upon the standard 60% of median income. The measure of absolute, or fixed, poverty was based upon the US poverty threshold. Our analyses were conducted on data for 30 countries between 1978 and 2010, a total of 149 data points. We separately studied infant, child, and adult mortality. Our findings highlight the importance of relative poverty for mortality. Especially for infant and child mortality, we found that our estimates of fixed poverty is close to zero either in the crude models, or when adjusting for gross domestic product. Conversely, the relative poverty estimates increased when adjusting for confounders. Our results seemed robust to a number of sensitivity tests. If we agree that risk of death is important, the public policy implication of our findings is that relative poverty, which has close associations to overall inequality, should be a major concern also among rich countries.

  1. Validation of band counts in eyestalks for the determination of age of Antarctic krill, Euphausia superba.

    Directory of Open Access Journals (Sweden)

    Raouf Kilada

    Full Text Available Using known-age Antarctic krill (Euphausia superba grown from eggs hatched at two different laboratories, we validate the annual pattern of bands deposited in the eyestalks of krill and determine the absolute age of these animals. Ages two through five years were validated, and these animals ranged from 37.1 to 62.6 mm in total length. The band counts in these individuals were either identical to their absolute ages, or only failed to agree by a few months, which demonstrates the accuracy of this method. Precision and bias were estimated graphically using Chang's index (Coefficient of Variation = 5.03%. High accuracy and precision between readers and low ageing bias indicate that longitudinal sections of eyestalks can be used to age krill in wild samples and to develop age-based stock assessment models for krill. Archival samples preserved in formalin (5% and stored in ambient conditions were also readable. Ageing preserved krill will provide the opportunity to examine changes in growth among krill populations within the Southern Ocean and to retrospectively examine changes in krill production over the last century to better understand the historical and future impacts of climate change on this critical Southern Ocean species.

  2. Cryogenic, Absolute, High Pressure Sensor

    Science.gov (United States)

    Chapman, John J. (Inventor); Shams. Qamar A. (Inventor); Powers, William T. (Inventor)

    2001-01-01

    A pressure sensor is provided for cryogenic, high pressure applications. A highly doped silicon piezoresistive pressure sensor is bonded to a silicon substrate in an absolute pressure sensing configuration. The absolute pressure sensor is bonded to an aluminum nitride substrate. Aluminum nitride has appropriate coefficient of thermal expansion for use with highly doped silicon at cryogenic temperatures. A group of sensors, either two sensors on two substrates or four sensors on a single substrate are packaged in a pressure vessel.

  3. Absolute Magnetization Distribution on Back-arc Spreading Axis Hosting Hydrothermal Vents; Insight from Shinkai 6500 Magnetic Survey

    Science.gov (United States)

    Fujii, M.; Okino, K.; Honsho, C.; Mochizuki, N.; Szitkar, F.; Dyment, J.

    2013-12-01

    Near-bottom magnetic profiling using submersible, deep-tow, Remotely Operated Vehicle (ROV) and Autonomous Underwater Vehicle (AUV) make possible to conduct high-resolution surveys and depict detailed magnetic features reflecting, for instance, the presence of fresh lavas or hydrothermal alteration, or geomagnetic paleo-intensity variations. We conducted near-bottom three component magnetic measurements onboard submersible Shinkai 6500 in the Southern Mariana Trough, where five active hydrothermal vent fields (Snail, Yamanaka, Archean, Pica, and Urashima sites) have been found in both on- and off-axis areas of the active back-arc spreading center, to detect signals from hydrothermally altered rock and to distinguish old and new submarine lava flows. Fourteen dives were carried out at an altitude of 1-40 m during the R/V Yokosuka YK10-10 and YK10-11 cruises in 2010. We carefully corrected the effect of the induced and permanent magnetizations of the submersible by applying the correction method for the shipboard three-component magnetometer measurement modified for deep-sea measurement, and subtracted the IGRF values from the corrected data to obtain geomagnetic vector anomalies along the dive tracks. We then calculated the synthetic magnetic vector field produced by seafloor, assumed to be uniformly magnetized, using three dimensional forward modeling. Finally, values of the absolute magnetizations were estimated by using a linear transfer function in the Fourier domain from the observed and synthetic magnetic anomalies. The distribution of estimated absolute magnetization generally shows low values around the five hydrothermal vent sites. This result is consistent with the equivalent magnetization distribution obtained from previous AUV survey data. The areas of low magnetization are also consistent with hydrothermal deposits identified in video records. These results suggest that low magnetic signals are due to hydrothermal alteration zones where host rocks are

  4. Challenging ICES age estimation protocols: lessons learned from the eastern Baltic cod stock

    DEFF Research Database (Denmark)

    Hüssy, Karin; Radtke, Krzysztof; Plikshs, Maris

    2016-01-01

    Over the recent decades, the International Council for the Exploration of the Sea (ICES) has set guidelines for best practise quality control of age estimation procedures. The applicability of these guidelines is assessed by reviewing the ageing issues of eastern Baltic cod (EBC) as a case study....

  5. Are morphometrics sufficient for estimating age of pre-fledging birds in the field? A test using common terns (Sterna hirundo.

    Directory of Open Access Journals (Sweden)

    Christy N Wails

    Full Text Available Age is a key component of fitness, affecting survival and reproductive capacities. Where it is not possible to study known individuals from birth, morphometrics (predominantly patterns of plumage development for birds are most often used to estimate age. Although criteria for age estimations exist for many species, the degree to which these criteria improve the precision of estimates remains to be tested, restricting their widespread acceptance. We develop a photographic tool for estimating ages of Common Tern (Sterna hirundo chicks and test it using 100 human observers of varying prior experience across four breeding colonies (three North American sites and one European site and under controlled laboratory conditions. We followed the design approach of other morphometric tools, expanding it to create a user-friendly guide (divided into six age groupings. The majority (86% of observers improved in chick-aging accuracy when using the tool by an average of 20.1% (±1.4 SE and correctly estimated 60.3% (±1.4 of chick ages. This was similar to the intrinsic aging ability of our best field observer (63.3%. Observers with limited experience showed the greatest increases in chick-aging accuracy over experienced observers who likely had established a method for estimating chick ages prior to using the tool. Even the best observers only correctly estimated ages of chicks 62.9% (±2.8 of the time in the field and 84.0% (±2.9 of the time in the lab when using the tool and typically underestimated ages. This indicates that developmental variation between individual chicks can prevent completely reliable age estimates and corroborates the few existing data that suggest that morphometric criteria fail to achieve robust levels of accuracy and may introduce error into studies that rely on them. We conclude that novel approaches for estimating age, not only morphometric criteria, must be pursued.

  6. Advancing Absolute Calibration for JWST and Other Applications

    Science.gov (United States)

    Rieke, George; Bohlin, Ralph; Boyajian, Tabetha; Carey, Sean; Casagrande, Luca; Deustua, Susana; Gordon, Karl; Kraemer, Kathleen; Marengo, Massimo; Schlawin, Everett; Su, Kate; Sloan, Greg; Volk, Kevin

    2017-10-01

    We propose to exploit the unique optical stability of the Spitzer telescope, along with that of IRAC, to (1) transfer the accurate absolute calibration obtained with MSX on very bright stars directly to two reference stars within the dynamic range of the JWST imagers (and of other modern instrumentation); (2) establish a second accurate absolute calibration based on the absolutely calibrated spectrum of the sun, transferred onto the astronomical system via alpha Cen A; and (3) provide accurate infrared measurements for the 11 (of 15) highest priority stars with no such data but with accurate interferometrically measured diameters, allowing us to optimize determinations of effective temperatures using the infrared flux method and thus to extend the accurate absolute calibration spectrally. This program is integral to plans for an accurate absolute calibration of JWST and will also provide a valuable Spitzer legacy.

  7. Racemization of aspartic acid in root dentin as a tool for age estimation in a Kuwaiti population.

    Science.gov (United States)

    Elfawal, Mohamed Amin; Alqattan, Sahib Issa; Ghallab, Noha Ayman

    2015-01-01

    Estimation of age is one of the most significant tasks in forensic practice. Amino acid racemization is considered one of the most reliable and accurate methods of age estimation and aspartic acid shows a high racemization reaction rate. The present study has investigated the application of aspartic acid racemization in age estimation in a Kuwaiti population using root dentin from a total of 89 upper first premolar teeth. The D/L ratio of aspartic acid was obtained by HPLC technique in a test group of 50 subjects and a linear regression line was established between aspartic acid racemization and age. The correlation coefficient (r) was 0.97, and the standard error of estimation was ±1.26 years. The racemization age "t" of each subject was calculated by applying the following formula: ln [(1 + D/L)/(1 - D/L)] = 0.003181 t + (-0.01591). When the proposed formula "estimated age t = ln [(1 + D/L)/(1 - D/L)] + 0.01591/0.003181" was applied to a validation group of 39 subjects, the range of error was less than one year in 82.1% of the cases and the standard error of estimation was ±1.12. The current work has established a reasonably significant correlation of the D-/L-aspartic acid ratio with age, and proposed an apparently reliable formula for calculating the age in Kuwaiti populations through aspartic acid racemization. Further research is required to find out whether similar findings are applicable to other ethnic populations. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  8. Mineralization of mandibular third molars can estimate chronological age--Brazilian indices.

    Science.gov (United States)

    de Oliveira, Fernando Toledo; Capelozza, Ana Lúcia Álvares; Lauris, José Roberto Pereira; de Bullen, Izabel Regina Fischer Rubira

    2012-06-10

    Forensic age estimation is an important element of anthropological research, as it produces one of the primary sources of data that researchers use to establish the identity of a person living or the identity of unknown bodily remains. The aim of this study was to determine if the chronology of third molar mineralization could be an accurate indicator of estimated age in a sample Brazilian population. If so, mineralization could determine the probability of an individual being 18 years or older. The study evaluated 407 panoramic radiographs of males and females from the past 5 years in order to assess the mineralization status of the mandibular third molars. The evaluation was carried out using an adaptation of Demirjian's system. The results indicated a strong correlation between chronological age and the mineralization of the mandibular third molars. The results indicated that modern Brazilian generation tends to demonstrate an earlier mandibular third molar mineralization than older Brazilian generation and people of other nationalities. Males reached developmental stages slightly earlier than females, but statistically significant differences between the sex were not found. The probability that an individual with third molar mineralization stage H had reached an age of 18 years or older was 96.8-98.6% for males and females, respectively. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  9. The use of absolute values improves performance of estimation formulae

    DEFF Research Database (Denmark)

    Redal-Baigorri, Belén; Rasmussen, Knud; Heaf, James Goya

    2013-01-01

    BACKGROUND: Estimation of Glomerular Filtration Rate (GFR) by equations such as Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) or Modification of Diet in Renal Disease (MDRD) is usually expressed as a Body Surface Area (BSA) indexed value (ml/min per 1.73 m²). This can have severe cl...

  10. Relative and Absolute Reliability of Timed Up and Go Test in Community Dwelling Older Adult and Healthy Young People

    Directory of Open Access Journals (Sweden)

    Farhad Azadi

    2014-01-01

    Full Text Available Objectives: Relative and absolute reliability are psychometric properties of the test that many clinical decisions are based on them. In many cases, only relative reliability takes into consideration while the absolute reliability is also very important. Methods & Materials: Eleven community-dwelling older adults aged 65 years and older (69.64±3.58 and 20 healthy young in the age range 20 to 35 years (28.80±4.15 using three versions of Timed Up and Go test were evaluated twice with an interval of 2 to 5 days. Results: Generally, the non-homogeneity of the study population was stratified to increase the Intra-class Correlation Coefficient (ICC this coefficient in elderly people is greater than young people and with a secondary task is reduced. In This study, absolute reliability indices using different data sources and equations lead to in more or less similar results. At general, in test–retest situations, the elderly more than the young people must be changed to be interpreted as a real change, not random. The random error contribution is slightly greater in elderly than young and with a secondary task is increased.It seems, heterogeneity leads to moderation in absolute reliability indices. Conclusion: In relative reliability studies, researchers and clinicians should pay attention to factors such as homogeneity of population and etc. As well as, absolute reliability beside relative reliability is needed and necessary in clinical decision making.

  11. ESTIMATION OF INTRINSIC AND EXTRINSIC ENVIRONMENT FACTORS OF AGE-RELATED TOOTH COLOUR CHANGES

    Czech Academy of Sciences Publication Activity Database

    Hyšpler, P.; Jezbera, D.; Fürst, T.; Mikšík, Ivan; Waclawek, M.

    2010-01-01

    Roč. 17, č. 4 (2010), s. 515-525 ISSN 1898-6196 Institutional research plan: CEZ:AV0Z50110509 Keywords : age-related colour changes of teeth * intrinsic and extrinsic factors * 3D mathematical regression models * estimation of real age Subject RIV: ED - Physiology Impact factor: 0.294, year: 2010

  12. Accounting for estimated IQ in neuropsychological test performance with regression-based techniques.

    Science.gov (United States)

    Testa, S Marc; Winicki, Jessica M; Pearlson, Godfrey D; Gordon, Barry; Schretlen, David J

    2009-11-01

    Regression-based normative techniques account for variability in test performance associated with multiple predictor variables and generate expected scores based on algebraic equations. Using this approach, we show that estimated IQ, based on oral word reading, accounts for 1-9% of the variability beyond that explained by individual differences in age, sex, race, and years of education for most cognitive measures. These results confirm that adding estimated "premorbid" IQ to demographic predictors in multiple regression models can incrementally improve the accuracy with which regression-based norms (RBNs) benchmark expected neuropsychological test performance in healthy adults. It remains to be seen whether the incremental variance in test performance explained by estimated "premorbid" IQ translates to improved diagnostic accuracy in patient samples. We describe these methods, and illustrate the step-by-step application of RBNs with two cases. We also discuss the rationale, assumptions, and caveats of this approach. More broadly, we note that adjusting test scores for age and other characteristics might actually decrease the accuracy with which test performance predicts absolute criteria, such as the ability to drive or live independently.

  13. NGS Absolute Gravity Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NGS Absolute Gravity data (78 stations) was received in July 1993. Principal gravity parameters include Gravity Value, Uncertainty, and Vertical Gradient. The...

  14. Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice.

    Science.gov (United States)

    Antoch, Marina P; Wrobel, Michelle; Kuropatwinski, Karen K; Gitlin, Ilya; Leonova, Katerina I; Toshkov, Ilia; Gleiberman, Anatoli S; Hutson, Alan D; Chernova, Olga B; Gudkov, Andrei V

    2017-03-19

    The development of healthspan-extending pharmaceuticals requires quantitative estimation of age-related progressive physiological decline. In humans, individual health status can be quantitatively assessed by means of a frailty index (FI), a parameter which reflects the scale of accumulation of age-related deficits. However, adaptation of this methodology to animal models is a challenging task since it includes multiple subjective parameters. Here we report a development of a quantitative non-invasive procedure to estimate biological age of an individual animal by creating physiological frailty index (PFI). We demonstrated the dynamics of PFI increase during chronological aging of male and female NIH Swiss mice. We also demonstrated acceleration of growth of PFI in animals placed on a high fat diet, reflecting aging acceleration by obesity and provide a tool for its quantitative assessment. Additionally, we showed that PFI could reveal anti-aging effect of mTOR inhibitor rapatar (bioavailable formulation of rapamycin) prior to registration of its effects on longevity. PFI revealed substantial sex-related differences in normal chronological aging and in the efficacy of detrimental (high fat diet) or beneficial (rapatar) aging modulatory factors. Together, these data introduce PFI as a reliable, non-invasive, quantitative tool suitable for testing potential anti-aging pharmaceuticals in pre-clinical studies.

  15. Third molar mineralization in relation to chronologic age estimation of the Han in central southern China.

    Science.gov (United States)

    Liu, Ying; Geng, Kun; Chu, Yanhao; Xu, Mindi; Zha, Lagabaiyila

    2018-03-03

    The purpose of this study is to provide a forensic reference data about estimating chronologic age by evaluating the third molar mineralization of Han in central southern China. The mineralization degree of third molars was assessed by Demirjian's classification with modification for 2519 digital orthopantomograms (1190 males, 1329 females; age 8-23 years). The mean ages of the initial mineralization and the crown completion of third molars were around 9.66 and 13.88 years old in males and 9.52 and 14.09 years old in females. The minimum ages of apical closure were around 16 years in both sexes. Twenty-eight at stage C and stage G and 38 and 48 at stage F occurred earlier in males than in females. There was no significant difference between maxillary and mandibular teeth in males and females except that stage C in males. Two formulas were devised to estimate age based on mineralization stages and sexes. In Hunan Province, the person will probably be over age 14, when a third molar reaches the stage G. The results of the study could provide reference for age estimation in forensic cases and clinical dentistry.

  16. Estimation of single-year-of-age counts of live births, fetal losses, abortions, and pregnant women for counties of Texas.

    Science.gov (United States)

    Singh, Bismark; Meyers, Lauren Ancel

    2017-05-08

    We provide a methodology for estimating counts of single-year-of-age live-births, fetal-losses, abortions, and pregnant women from aggregated age-group counts. As a case study, we estimate counts for the 254 counties of Texas for the year 2010. We use interpolation to estimate counts of live-births, fetal-losses, and abortions by women of each single-year-of-age for all Texas counties. We then use these counts to estimate the numbers of pregnant women for each single-year-of-age, which were previously available only in aggregate. To support public health policy and planning, we provide single-year-of-age estimates of live-births, fetal-losses, abortions, and pregnant women for all Texas counties in the year 2010, as well as the estimation method source code.

  17. Absolute isotopic abundances of Ti in meteorites

    International Nuclear Information System (INIS)

    Niederer, F.R.; Papanastassiou, D.A.; Wasserburg, G.J.

    1985-01-01

    The absolute isotope abundance of Ti has been determined in Ca-Al-rich inclusions from the Allende and Leoville meteorites and in samples of whole meteorites. The absolute Ti isotope abundances differ by a significant mass dependent isotope fractionation transformation from the previously reported abundances, which were normalized for fractionation using 46 Ti/ 48 Ti. Therefore, the absolute compositions define distinct nucleosynthetic components from those previously identified or reflect the existence of significant mass dependent isotope fractionation in nature. We provide a general formalism for determining the possible isotope compositions of the exotic Ti from the measured composition, for different values of isotope fractionation in nature and for different mixing ratios of the exotic and normal components. The absolute Ti and Ca isotopic compositions still support the correlation of 50 Ti and 48 Ca effects in the FUN inclusions and imply contributions from neutron-rich equilibrium or quasi-equilibrium nucleosynthesis. The present identification of endemic effects at 46 Ti, for the absolute composition, implies a shortfall of an explosive-oxygen component or reflects significant isotope fractionation. Additional nucleosynthetic components are required by 47 Ti and 49 Ti effects. Components are also defined in which 48 Ti is enhanced. Results are given and discussed. (author)

  18. Digitized morphometric analysis of dental pulp of permanent mandibular second molar for age estimation of Davangere population.

    Science.gov (United States)

    Kumar, Nerella Narendra; Panchaksharappa, Mamatha Gowda; Annigeri, Rajeshwari G

    2016-04-01

    The aim of the present study is to estimate the age of Davangere population by evaluating the pulp to tooth area ratio (PTR) by using digitized intraoral periapical radiographs of permanent mandibular second molar. 400 intraoral periapical radiograph (IOPA) of permanent mandibular 2nd molar of both the sexes aged 14-60 years were used. Digital camera was used to image the radiographs. Images were computed and PTR was calculated by AUTOCAD software. Intra and Inter observer variability was also assessed. Regression analysis was used to estimate the age of an individual by taking PTR as dependent variable. The mean PTR of males and females was 0.10 ± 0.02 and 0.09 ± 0.02 respectively. Negative correlation was observed, when age was compared with PTR {r = -0.441, -0.406 & -0.419 among males, females and total subjects (p AUTOCAD software. Also high differences were observed between estimated and chronological age of 12 years which is not in the acceptable range. But it provides a new window for research in the forensic sciences in estimating the adult age. Copyright © 2016 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  19. Do Individual Differences and Aging Effects in the Estimation of Geographical Slant Reflect Cognitive or Perceptual Effects?

    Directory of Open Access Journals (Sweden)

    Abigail M. Dean

    2016-07-01

    Full Text Available Several individual differences including age have been suggested to affect the perception of slant. A cross-sectional study of outdoor hill estimation (N = 106 was analyzed using individual difference measures of age, experiential knowledge, fitness, personality traits, and sex. Of particular note, it was found that for participants who reported any experiential knowledge about slant, estimates decreased (i.e., became more accurate as conscientiousness increased, suggesting that more conscientious individuals were more deliberate about taking their experiential knowledge (rather than perception into account. Effects of fitness were limited to those without experiential knowledge, suggesting that they, too, may be cognitive rather than perceptual. The observed effects of age, which tended to produce lower, more accurate estimates of hill slant, provide more evidence that older adults do not see hills as steeper. The main effect of age was to lower slant estimates; such effects may be due to implicit experiential knowledge acquired over a lifetime. The results indicate the impact of cognitive, rather than perceptual factors on individual differences in slant estimation.

  20. STAR barrel electromagnetic calorimeter absolute calibration using 'minimum ionizing particles' from collisions at RHIC

    International Nuclear Information System (INIS)

    Cormier, T.M.; Pavlinov, A.I.; Rykov, M.V.; Rykov, V.L.; Shestermanov, K.E.

    2002-01-01

    The procedure for the STAR Barrel Electromagnetic Calorimeter (BEMC) absolute calibrations, using penetrating charged particle hits (MIP-hits) from physics events at RHIC, is presented. Its systematic and statistical errors are evaluated. It is shown that, using this technique, the equalization and transfer of the absolute scale from the test beam can be done to a percent level accuracy in a reasonable amount of time for the entire STAR BEMC. MIP-hits would also be an effective tool for continuously monitoring the variations of the BEMC tower's gains, virtually without interference to STAR's main physics program. The method does not rely on simulations for anything other than geometric and some other small corrections, and also for estimations of the systematic errors. It directly transfers measured test beam responses to operations at RHIC

  1. Dental age estimation in a Brazilian adult population using Cameriere’s method

    Directory of Open Access Journals (Sweden)

    Alana de Cássia Silva AZEVEDO

    2015-01-01

    Full Text Available The objectives of this study were to develop a specific formula to estimate age in a Brazilian adult population and to compare the original formula from Cameriere to this Brazilian formula. The sample comprised 1,772 periapical radiographs from 443 subjects (219 men, 224 women that were organized into 12 groups according to sex (men or women and age (20-29, 30-39, 40-49, 50-59, 60-69, and 70 years and older. The films were analyzed using the criteria described by Cameriere et al. (2004 and Adobe Photoshop®. We obtained a mean error of 8.56 (SD = 5.80 years for tooth 13, 7.99 (SD = 5.78 years for tooth 23, 8.38 (SD = 6.26 years for tooth 33, and 8.20 (SD = 6.54 years for tooth 43. When teeth were combined in the analysis, we observed lower mean errors. The Brazilian formula developed from this sample group was more accurate than Cameriere’s formula. However, other factors must be considered to improve age estimates in adults.

  2. Investigating Absolute Value: A Real World Application

    Science.gov (United States)

    Kidd, Margaret; Pagni, David

    2009-01-01

    Making connections between various representations is important in mathematics. In this article, the authors discuss the numeric, algebraic, and graphical representations of sums of absolute values of linear functions. The initial explanations are accessible to all students who have experience graphing and who understand that absolute value simply…

  3. Performances of some estimators of linear model with ...

    African Journals Online (AJOL)

    The estimators are compared by examing the finite properties of estimators namely; sum of biases, sum of absolute biases, sum of variances and sum of the mean squared error of the estimated parameter of the model. Results show that when the autocorrelation level is small (ρ=0.4), the MLGD estimator is best except when ...

  4. Modeling mangrove biomass using remote sensing based age and growth estimates

    Science.gov (United States)

    Lagomasino, D.; Fatoyinbo, T. E.; Feliciano, E. A.; Lee, S. K.; Trettin, C.; Mangora, M.; Rahman, M.

    2016-12-01

    Mangroves are highly regarded coastal forests because of their ecosystem services and high carbon storage potential. In addition, these forests can develop rapidly in locations where congenial environmental conditions and sediment supply are available. Monitoring the growth and age of developing mangrove forests is crucial for sustainable management and estimating carbon stocks. Combining imagery from radar and optical satellites (e.g., TanDEM-X and Landsat), we can estimate young mangrove growth and age at regional and continental scales. We used TanDEM-X radar interferometry for modeling canopy height in 2013 and Landsat to measure land cover change from 1990 to 2013. Annual NDVI composites were determined for each calendar year between 1990 and 2013. New land areas gained from the transition of water to vegetation were determined by the differences in annual NDVI composites and the reference year 2013. The year of the greatest NDVI difference that met the threshold criteria was used as the initial tree height (0 m). Annual canopy height growth rates were estimated by the duration between land generation times and 2013 canopy height models derived from TanDEM-X and very-high resolution optical data. In this presentation, we compare growth rates and biomass accumulation in mangrove forests at four river deltas; the Zambezi (Mozambique), Rufiji (Tanzania), Ganges (Bangladesh), and Mekong (Vietnam). The spatial patterns of growth rates coincided with characteristic successional paradigms and stream morphology, where the maximum growth rates typically occurred along prograding creek banks. Initial comparisons between height-only and growth-age biomass indicate that the latter tend to overestimate biomass for younger forest stands of similar height. Both the vertical (e.g., canopy height) and horizontal (e.g., expansion) growth rates measured from remote sensing can garner important information regarding mangrove succession and primary productivity. Continued research

  5. Estimating stock parameters from trawl cpue-at-age series using year-class curves

    NARCIS (Netherlands)

    Cotter, A.J.R.; Mesnil, B.; Piet, G.J.

    2007-01-01

    A year-class curve is a plot of log cpue (catch per unit effort) over age for a single year class of a species (in contrast to the better known catch curve, fitted to multiple year classes at one time). When linear, the intercept and slope estimate the log cpue at age 0 and the average rate of total

  6. Should total landings be used to correct estimated catch in numbers or mean-weight-at-age?

    DEFF Research Database (Denmark)

    Lewy, Peter; Lassen, H.

    1997-01-01

    Many ICES fish stock assessment working groups have practised Sum Of Products, SOP, correction. This correction stems from a comparison of total weights of the known landings and the SOP over age of catch in number and mean weight-at-age, which ideally should be identical. In case of SOP...... discrepancies some countries correct catch in numbers while others correct mean weight-at-age by a common factor, the ratio between landing and SOP. The paper shows that for three sampling schemes the SOP corrections are statistically incorrect and should not be made since the SOP is an unbiased estimate...... of the total landings. Calculation of the bias of estimated catch in numbers and mean weight-at-age shows that SOP corrections of either of these estimates may increase the bias. Furthermore, for five demersal and one pelagic North Sea species it is shown that SOP discrepancies greater than 2% from...

  7. Dental age estimation in the living after completion of third molar mineralization: new data for Gustafson's criteria.

    Science.gov (United States)

    Timme, M; Timme, W H; Olze, A; Ottow, C; Ribbecke, S; Pfeiffer, H; Dettmeyer, R; Schmeling, A

    2017-03-01

    There is a need for dental age estimation methods after completion of the third molar mineralization. Degenerative dental characteristics appear to be suitable for forensic age diagnostics beyond the 18th year of life. In 2012, Olze et al. investigated the criteria studied by Gustafson using orthopantomograms. The objective of this study was to prove the applicability and reliability of this method with a large cohort and a wide age range, including older individuals. For this purpose, 2346 orthopantomograms of 1167 female and 1179 male Germans aged 15 to 70 years were reviewed. The characteristics of secondary dentin formation, cementum apposition, periodontal recession and attrition were evaluated in all the mandibular premolars. The correlation of the individual characteristics with the chronological age was examined by means of a stepwise multiple regression analysis, in which the chronological age formed the dependent variable. Following those results, R 2 values amounted to 0.73 to 0.8; the standard error of estimate was 6.8 to 8.2 years. Fundamentally, the recommendation for conducting age estimations in the living by these methods can be shared. The values for the quality of the regression are, however, not precise enough for a reliable age estimation around regular retirement date ages. More precise regression formulae for the age group of 15 to 40 years of life are separately presented in this study. Further research should investigate the influence of ethnicity, dietary habits and modern health care on the degenerative characteristics in question.

  8. Application of a novel method for age estimation of a baleen whale and a porpoise

    DEFF Research Database (Denmark)

    Nielsen, Nynne H.; Garde, Eva; Heide-Jørgensen, Mads Peter

    2013-01-01

    Eyeballs from 121 fin whales (Balaenoptera physalus) and 83 harbor porpoises (Phocoena phocoena) were used for age estimation using the aspartic acid racemization (AAR) technique. The racemization rate (kAsp) for fin whales was established from 15 fetuses (age 0) and 15 adult whales where age...

  9. Approach To Absolute Zero

    Indian Academy of Sciences (India)

    more and more difficult to remove heat as one approaches absolute zero. This is the ... A new and active branch of engineering ... This temperature is called the critical temperature, Te' For sulfur dioxide the critical ..... adsorbent charcoal.

  10. High-precision gravity measurements using absolute and relative gravimeters at Mount Etna (Sicily, Italy

    Directory of Open Access Journals (Sweden)

    Ciro Del Negro

    2011-12-01

    Full Text Available Accurate detection of time gravity changes attributable to the dynamics of volcanoes requires high-precision gravity measurements. With the aim of improving the quality of data from the Mount Etna gravity network, we used both absolute and relative gravimeters in a hybrid method. In this report, some of the techniques for gravity surveys are reviewed, and the results related to each method are compared. We show how the total uncertainty estimated for the gravity measurements performed with this combined use of absolute and relative gravimeters is roughly comparable to that calculated when the measurements are acquired using only relative gravimeters (the traditional method. However, the data highlight how the hybrid approach improves the measurement capabilities for surveying the Mount Etna volcanic area. This approach enhances the accuracy of the data, and then of the four-dimensional surveying, which minimizes ambiguities inherent in the gravity measurements. As a case study, we refer to two gravity datasets acquired in 2005 and 2010 from the western part of the Etna volcano, which included five absolute and 13 relative stations of the Etna gravity network.

  11. Age estimation by pulp-to-tooth area ratio using cone-beam computed tomography: A preliminary analysis.

    Science.gov (United States)

    Rai, Arpita; Acharya, Ashith B; Naikmasur, Venkatesh G

    2016-01-01

    Age estimation of living or deceased individuals is an important aspect of forensic sciences. Conventionally, pulp-to-tooth area ratio (PTR) measured from periapical radiographs have been utilized as a nondestructive method of age estimation. Cone-beam computed tomography (CBCT) is a new method to acquire three-dimensional images of the teeth in living individuals. The present study investigated age estimation based on PTR of the maxillary canines measured in three planes obtained from CBCT image data. Sixty subjects aged 20-85 years were included in the study. For each tooth, mid-sagittal, mid-coronal, and three axial sections-cementoenamel junction (CEJ), one-fourth root level from CEJ, and mid-root-were assessed. PTR was calculated using AutoCAD software after outlining the pulp and tooth. All statistical analyses were performed using an SPSS 17.0 software program. Linear regression analysis showed that only PTR in axial plane at CEJ had significant age correlation ( r = 0.32; P < 0.05). This is probably because of clearer demarcation of pulp and tooth outline at this level.

  12. Absolute GPS Positioning Using Genetic Algorithms

    Science.gov (United States)

    Ramillien, G.

    A new inverse approach for restoring the absolute coordinates of a ground -based station from three or four observed GPS pseudo-ranges is proposed. This stochastic method is based on simulations of natural evolution named genetic algorithms (GA). These iterative procedures provide fairly good and robust estimates of the absolute positions in the Earth's geocentric reference system. For comparison/validation, GA results are compared to the ones obtained using the classical linearized least-square scheme for the determination of the XYZ location proposed by Bancroft (1985) which is strongly limited by the number of available observations (i.e. here, the number of input pseudo-ranges must be four). The r.m.s. accuracy of the non -linear cost function reached by this latter method is typically ~10-4 m2 corresponding to ~300-500-m accuracies for each geocentric coordinate. However, GA can provide more acceptable solutions (r.m.s. errors < 10-5 m2), even when only three instantaneous pseudo-ranges are used, such as a lost of lock during a GPS survey. Tuned GA parameters used in different simulations are N=1000 starting individuals, as well as Pc=60-70% and Pm=30-40% for the crossover probability and mutation rate, respectively. Statistical tests on the ability of GA to recover acceptable coordinates in presence of important levels of noise are made simulating nearly 3000 random samples of erroneous pseudo-ranges. Here, two main sources of measurement errors are considered in the inversion: (1) typical satellite-clock errors and/or 300-metre variance atmospheric delays, and (2) Geometrical Dilution of Precision (GDOP) due to the particular GPS satellite configuration at the time of acquisition. Extracting valuable information and even from low-quality starting range observations, GA offer an interesting alternative for high -precision GPS positioning.

  13. Absolute spectrophotometry of Nova Cygni 1975

    International Nuclear Information System (INIS)

    Kontizas, E.; Kontizas, M.; Smyth, M.J.

    1976-01-01

    Radiometric photoelectric spectrophotometry of Nova Cygni 1975 was carried out on 1975 August 31, September 2, 3. α Lyr was used as reference star and its absolute spectral energy distribution was used to reduce the spectrophotometry of the nova to absolute units. Emission strengths of Hα, Hβ, Hγ (in W cm -2 ) were derived. The Balmer decrement Hα:Hβ:Hγ was compared with theory, and found to deviate less than had been reported for an earlier nova. (author)

  14. The Pragmatics of "Unruly" Dative Absolutes in Early Slavic

    Directory of Open Access Journals (Sweden)

    Daniel E. Collins

    2011-08-01

    Full Text Available This chapter examines some uses of the dative absolute in Old Church Slavonic and in early recensional Slavonic texts that depart from notions of how Indo-European absolute constructions should behave, either because they have subjects coreferential with the (putative main-clause subjects or because they function as if they were main clauses in their own right. Such "noncanonical" absolutes have generally been written off as mechanistic translations or as mistakes by scribes who did not understand the proper uses of the construction. In reality, the problem is not with literalistic translators or incompetent scribes but with the definition of the construction itself; it is quite possible to redefine the Early Slavic dative absolute in a way that accounts for the supposedly deviant cases. While the absolute is generally dependent semantically on an adjacent unit of discourse, it should not always be regarded as subordinated syntactically. There are good grounds for viewing some absolutes not as dependent clauses but as independent sentences whose collateral character is an issue not of syntax but of the pragmatics of discourse.

  15. Absolute measurement of thermal neutron fluence and its application for fission track dating

    International Nuclear Information System (INIS)

    Ganzawa, Yoshihiro; Honda, Teruyuki; Nozaki, Tetsuya.

    1988-01-01

    The absolute measurements of thermal neutron fluence for fission track dating have been developed after the proceeding results of Honda et al. (1987). The 2,200 m/sec activation cross section of 197 Au (98.8 barn) is corrected to 87.4 barn (σa) by the three factors of the neutron temperature, Maxwellian distribution of thermal neutrons and non 1/v correction factor for the above absolute measurement. The calibrated factor (B th ) of standard glasses (SRM613, SRM962a, CN-1 and CN-2) and zeta-a (ζa) values for fission track dating are determined on the basis of these experimental results. The values of B th , (7.47 ± 0.29) x 10 9 for SRM613, (7.43 ± 0.34) x 10 9 for SRM962a, (2.50 ± 0.06) x 10 9 for CN-1 and (2.74 ± 0.06) x 10 9 for CN-2 closely agree with those reported previously by Honda et al. (1987). Further, the ζa values of 392.3 ± 16.5 for SRM962a and SRM613, 131.4 ± 3.1 for CN-1 and 144.1 ± 3.3 for CN-2 calculated from B th , effective thermal neutron fission cross-section σf (497.4 barn), isotopic abundance ratio 235 U/ 239 U, I (7.2527 x 10 -3 ) and spontaneous fission decay constant of 238 U, λ f (6.85 x 10 -17 a -7 ) show close agreement with ζ b values (392.5 ± 10.0, 131.6 ± 3.3, 140.1 ± 3.5) derived from the absolute age of Fish Canyon Tuff (27.9 ± 0.7 Ma) respectively. The fission track dating of zircons separated from Oligocene-Miocene tuff distributed in Eastern Hokkaido have been carried out by the external detector method using ζ a . The obtained ages are 28.6 ± 0.7 Ma (1 - 2) and 23.3 ± 0.7 Ma (3 - 2). These results agree well with the geologic age supported from Ashoro Fossil Fauna, K-Ar ages of volcanic rocks and stratigraphy in this area. (author)

  16. Distance estimation experiment for aerial minke whale surveys

    Directory of Open Access Journals (Sweden)

    Lars Witting

    2009-09-01

    Full Text Available A comparative study between aerial cue–counting and digital photography surveys for minke whales conducted in Faxaflói Bay in September 2003 is used to check the perpendicular distances estimated by the cue-counting observers. The study involved 2 aircraft with the photo plane at 1,700 feet flying above the cue–counting plane at 750 feet. The observer–based distance estimates were calculated from head angles estimated by angle-boards and declination angles estimated by declinometers. These distances were checked against image–based estimates of the perpendicular distance to the same whale. The 2 independent distance estimates were obtained for 21 sightings of minke whale, and there was a good agreement between the 2 types of estimates. The relative absolute deviations between the 2 estimates were on average 23% (se: 6%, with the errors in the observer–based distance estimates resembling that of a log-normal distribution. The linear regression of the observer–based estimates (obs on the image–based estimates (img was Obs=1.1Img (R2=0.85 with an intercept fixed at zero. There was no evidence of a distance estimation bias that could generate a positive bias in the absolute abundance estimated by cue–counting.

  17. FUNDAMENTAL PARAMETERS AND SPECTRAL ENERGY DISTRIBUTIONS OF YOUNG AND FIELD AGE OBJECTS WITH MASSES SPANNING THE STELLAR TO PLANETARY REGIME

    Energy Technology Data Exchange (ETDEWEB)

    Filippazzo, Joseph C.; Rice, Emily L. [Department of Engineering Science and Physics, College of Staten Island, City University of New York, 2800 Victory Blvd, Staten Island, NY 10314 (United States); Faherty, Jacqueline; Cruz, Kelle L. [Department of Astrophysics, American Museum of Natural History, New York, NY 10024 (United States); Van Gordon, Mollie M. [Department of Geography, University of California, Berkeley, CA 94720 (United States); Looper, Dagny L. [Tisch School of the Arts, New York University, New York, NY 10003 (United States)

    2015-09-10

    We combine optical, near-infrared, and mid-infrared spectra and photometry to construct expanded spectral energy distributions for 145 field age (>500 Myr) and 53 young (lower age estimate <500 Myr) ultracool dwarfs (M6-T9). This range of spectral types includes very low mass stars, brown dwarfs, and planetary mass objects, providing fundamental parameters across both the hydrogen and deuterium burning minimum masses for the largest sample assembled to date. A subsample of 29 objects have well constrained ages as probable members of a nearby young moving group. We use 182 parallaxes and 16 kinematic distances to determine precise bolometric luminosities (L{sub bol}) and radius estimates from evolutionary models give semi-empirical effective temperatures (T{sub eff}) for the full range of young and field age late-M, L, and T dwarfs. We construct age-sensitive relationships of luminosity, temperature, and absolute magnitude as functions of spectral type and absolute magnitude to disentangle the effects of degenerate physical parameters such as T{sub eff}, surface gravity, and clouds on spectral morphology. We report bolometric corrections in J for both field age and young objects and find differences of up to a magnitude for late-L dwarfs. Our correction in Ks shows a larger dispersion but not necessarily a different relationship for young and field age sequences. We also characterize the NIR–MIR reddening of low gravity L dwarfs and identify a systematically cooler T{sub eff} of up to 300 K from field age objects of the same spectral type and 400 K cooler from field age objects of the same M{sub H} magnitude.

  18. A method for estimating age of medieval sub-adults from infancy to adulthood based on long bone length

    DEFF Research Database (Denmark)

    Primeau, Charlotte; Friis, Laila Saidane; Sejrsen, Birgitte

    2016-01-01

    OBJECTIVES: To develop a series of regression equations for estimating age from length of long bones for archaeological sub-adults when aging from dental development cannot be performed. Further, to compare derived ages when using these regression equations, and two other methods. MATERIAL AND ME...... as later than the medieval period, although this would require further testing. The quadratic equations are suggested to yield more accurate ages then using simply linear regression equations. Am J Phys Anthropol, 2015. © 2015 Wiley Periodicals, Inc.......OBJECTIVES: To develop a series of regression equations for estimating age from length of long bones for archaeological sub-adults when aging from dental development cannot be performed. Further, to compare derived ages when using these regression equations, and two other methods. MATERIAL...... AND METHODS: A total of 183 skeletal sub-adults from the Danish medieval period, were aged from radiographic images. Linear regression formulae were then produced for individual bones. Age was then estimated from the femur length using three different methods: equations developed in this study, data based...

  19. Absolutyzm i pluralizm (ABSOLUTISM AND PLURALISM

    Directory of Open Access Journals (Sweden)

    Renata Ziemińska

    2005-06-01

    Full Text Available Alethic absolutism is a thesis that propositions can not be more or less true, that they are true or false for ever (if true at all and that their truth is independent on any circumstances of their assertion. In negative version, easier to defend, alethic absolutism claims the very same proposition can not be both true and false relative to circumstances of its assertion. Simple alethic pluralism is a thesis that we have many concepts of truth. It is a very good way to dissolve the controversy between alethic relativism and absolutism. Many philosophical concepts of truth are the best reason for such pluralism. If concept is meaning of a name, we have many concepts of truth because the name 'truth' was understood in many ways. The variety of meanings however can be superficial. Under it we can find one idea of truth expressed in correspondence truism or schema (T. The content of the truism is too poor to be content of anyone concept of truth, so it usually is connected with some picture of the world (ontology and we have so many concepts of truth as many pictures of the world. The authoress proposes the hierarchical pluralism with privileged classic (or correspondence in weak sense concept of truth as absolute property.Other author's publications:

  20. Stratigraphy, correlation, and age estimates for fossils from Area 123, Koobi Fora.

    Science.gov (United States)

    Feibel, Craig S; Lepre, Christopher J; Quinn, Rhonda L

    2009-08-01

    Geological data from the Bura Hasuma region at Koobi Fora provide important constraints for estimating the ages of hominin fossils recovered there, including the cranium KNM-ER 1813. Strata of the upper Burgi, KBS, and Okote members in this part of Koobi Fora reflect three depositional regimes driven by changing paleogeography through time. The upper Burgi and lowermost KBS sequence in the southern Bura Hasuma region accumulated in a lacustrine to delta front setting, with highly localized depositional patterns, limiting the lateral extent of lithostratigraphic markers. Farther north, uppermost upper Burgi through KBS member strata document a fluctuating lake margin, with complex facies patterns. This interval is marked by laterally extensive lithostratigraphic markers, including molluscan packstones, beach sandstones, and stromatolite beds. The uppermost KBS and Okote members show a transition to dominantly fluvial character, with localized and discontinuous accumulation. An age model for the richly fossiliferous Area 123 sequence demonstrates the complexity of terrestrial accumulation patterns. Early lacustrine and delta front accumulation is marked by fairly continuous sedimentation, and high accumulation rates (up to ca. 91 cm/k.yr.). The fluctuating lake margin interval reflects lower sedimentation rates coupled with intervals of exposure, decreasing accumulation significantly (to ca. 13 cm/k.yr.). The capping fluvial interval is marked by significant erosion surfaces, breaks which may drop the overall accumulation rate even lower (ca. 0.3 cm/k.yr.). The data provided here establish a geological framework at odds with a recent proposal of ages considerably younger (by ca. 250 k.yr.) for many of the fossils from Area 123 and elsewhere. Tests of age models demonstrate that the younger ages are not possible. While minor refinements to age estimates for fossils are indicated by improved chronostratigraphic control, in the case of KNM-ER 1813, an age of younger

  1. Introducing the Mean Absolute Deviation "Effect" Size

    Science.gov (United States)

    Gorard, Stephen

    2015-01-01

    This paper revisits the use of effect sizes in the analysis of experimental and similar results, and reminds readers of the relative advantages of the mean absolute deviation as a measure of variation, as opposed to the more complex standard deviation. The mean absolute deviation is easier to use and understand, and more tolerant of extreme…

  2. Predictors of VO2Peak in children age 6- to 7-years-old

    DEFF Research Database (Denmark)

    Dencker, Magnus; Hermansen, Bianca; Bugge, Anna

    2011-01-01

    This study investigated the predictors of aerobic fitness (VO2PEAK) in young children on a population-base. Participants were 436 children (229 boys and 207 girls) aged 6.7 ± 0.4 yrs. VO2PEAK was measured during a maximal treadmill exercise test. Physical activity was assessed by accelerometers....... Total body fat and total fat free mass were estimated from skinfold measurements. Regression analyses indicated that significant predictors for VO2PEAK per kilogram body mass were total body fat, maximal heart rate, sex, and age. Physical activity explained an additional 4-7%. Further analyses showed...... the main contributing factors for absolute values of VO2PEAK were fat free mass, maximal heart rate, sex, and age. Physical activity explained an additional 3-6%....

  3. Absolute calibration in vivo measurement systems

    International Nuclear Information System (INIS)

    Kruchten, D.A.; Hickman, D.P.

    1991-02-01

    Lawrence Livermore National Laboratory (LLNL) is currently investigating a new method for obtaining absolute calibration factors for radiation measurement systems used to measure internally deposited radionuclides in vivo. Absolute calibration of in vivo measurement systems will eliminate the need to generate a series of human surrogate structures (i.e., phantoms) for calibrating in vivo measurement systems. The absolute calibration of in vivo measurement systems utilizes magnetic resonance imaging (MRI) to define physiological structure, size, and composition. The MRI image provides a digitized representation of the physiological structure, which allows for any mathematical distribution of radionuclides within the body. Using Monte Carlo transport codes, the emission spectrum from the body is predicted. The in vivo measurement equipment is calibrated using the Monte Carlo code and adjusting for the intrinsic properties of the detection system. The calibration factors are verified using measurements of existing phantoms and previously obtained measurements of human volunteers. 8 refs

  4. Incorrect Weighting of Absolute Performance in Self-Assessment

    Science.gov (United States)

    Jeffrey, Scott A.; Cozzarin, Brian

    Students spend much of their life in an attempt to assess their aptitude for numerous tasks. For example, they expend a great deal of effort to determine their academic standing given a distribution of grades. This research finds that students use their absolute performance, or percentage correct as a yardstick for their self-assessment, even when relative standing is much more informative. An experiment shows that this reliance on absolute performance for self-evaluation causes a misallocation of time and financial resources. Reasons for this inappropriate responsiveness to absolute performance are explored.

  5. Estimating time-based instantaneous total mortality rate based on the age-structured abundance index

    Science.gov (United States)

    Wang, Yingbin; Jiao, Yan

    2015-05-01

    The instantaneous total mortality rate ( Z) of a fish population is one of the important parameters in fisheries stock assessment. The estimation of Z is crucial to fish population dynamics analysis, abundance and catch forecast, and fisheries management. A catch curve-based method for estimating time-based Z and its change trend from catch per unit effort (CPUE) data of multiple cohorts is developed. Unlike the traditional catch-curve method, the method developed here does not need the assumption of constant Z throughout the time, but the Z values in n continuous years are assumed constant, and then the Z values in different n continuous years are estimated using the age-based CPUE data within these years. The results of the simulation analyses show that the trends of the estimated time-based Z are consistent with the trends of the true Z, and the estimated rates of change from this approach are close to the true change rates (the relative differences between the change rates of the estimated Z and the true Z are smaller than 10%). Variations of both Z and recruitment can affect the estimates of Z value and the trend of Z. The most appropriate value of n can be different given the effects of different factors. Therefore, the appropriate value of n for different fisheries should be determined through a simulation analysis as we demonstrated in this study. Further analyses suggested that selectivity and age estimation are also two factors that can affect the estimated Z values if there is error in either of them, but the estimated change rates of Z are still close to the true change rates. We also applied this approach to the Atlantic cod ( Gadus morhua) fishery of eastern Newfoundland and Labrador from 1983 to 1997, and obtained reasonable estimates of time-based Z.

  6. Absolute measurement of cerebral optical coefficients, hemoglobin concentration and oxygen saturation in old and young adults with near-infrared spectroscopy

    Science.gov (United States)

    We present near-infrared spectroscopy measurement of absolute cerebral hemoglobin concentration and saturation in a large sample of 36 healthy elderly (mean age, 85 ± 6 years) and 19 young adults (mean age, 28 ± 4 years). Non-invasive measurements were obtained on the forehead using a commercially a...

  7. Estimation of fracture toughness of cast stainless steels during thermal aging in LWR systems-revision 1

    International Nuclear Information System (INIS)

    Chopra, O.K.

    1994-08-01

    This report presents a revision of the procedure and correlations presented earlier in NUREG/CR-4513, ANL-90/42 (June 1991) for predicting the change in mechanical properties of cast stainless steel components due to thermal aging during service in light water reactors at 280-330 degrees C (535-625 degrees F). The correlations presented in this report are based on an expanded data base and have been optimized with mechanical-property data on cast stainless steels aged up to ∼58,000 h at 290-350 degrees C (554-633 degrees F). The fracture toughness J-R curve, tensile stress, and Charpy-impact energy of aged cast stainless steels are estimated from known material information. Mechanical properties of a specific cast stainless steel are estimated from the extent and kinetics of thermal embrittlement. Embrittlement of cast stainless steels is characterized in terms of room-temperature Charpy-impact energy. Charpy-impact energy as a function of time and temperature of reactor service is estimated from the kinetics of thermal embrittlement, which are also determined from the chemical composition. The initial impact energy of the unaged steel is required for these estimations. Initial tensile flow stress is needed for estimating the flow stress of the aged material. The fracture toughness J-R curve for the material is then obtained by correlating room-temperature Charpy-impact energy with fracture toughness parameters. The values of J IC are determined from the estimated J-R curve and flow stress. A common open-quotes predicted lower-boundclose quotes J-R curve for cast stainless steels of unknown chemical composition is also defined for a given grade of steel, range of ferrite content, and temperature. Examples of estimating mechanical properties of cast stainless steel components during reactor service are presented

  8. Evaluation of third molar development in the estimation of chronological age.

    Science.gov (United States)

    Soares, Caio Belém Rodrigues Barros; Figueiroa, José Natal; Dantas, Renata Moura Xavier; Kurita, Lúcio Mitsuo; Pontual, Andréa dos Anjos; Ramos-Perez, Flávia Maria de Moraes; Perez, Danyel Elias da Cruz; Pontual, Maria Luiza dos Anjos

    2015-09-01

    The purpose of this study was to evaluate the correlation between chronological age and the degree of third molar mineralization by Demirjian's developmental stages (Demirjian et al., 1973) using panoramic radiography. From a total of 11.396 digital panoramic radiographs of patients from three oral radiology private clinics from the northeast region of Brazil, obtained from January to June 2009, 2097 radiographic images from patients aged between 6 and 22 years were selected. The images were analyzed individually by two obsevers using a 21-inch computer screen and Windows Picture and Fax Viewer. Reliability was achieved by intra- and interobserver evaluation, using the Kappa test. Chronological age, calcification stage, gender and third molar were interrelated using a multiple linear regression model, considering age as a response variable. There was reliability with Demirjian et al.'s developmental stage assesment, displaying a significant relationship between mineralization stages and patients' age (Page and the calcification stage taking gender and localization of the third molar into consideration. It is possible to estimate chronological age based on Demirjian's stage of a third molar, regardless of gender and location. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  9. Estimation of Genetic Parameters for Real-time Ultrasound Measurements for Hanwoo Cows at Different Ages and Pregnancy Status

    Directory of Open Access Journals (Sweden)

    J. H. Lee

    2014-02-01

    Full Text Available The purpose of this study was to estimate genetic parameters of ultrasound measurements for longissimus dorsi muscle area (LMA, backfat thickness (BFT, and marbling score (MS in Hanwoo cows (N = 3,062 at the ages between 18 and 42 months. Data were collected from 100 Hanwoo breeding farms in Gyeongbuk province, Korea, in 2007 and 2008. The cows were classified into four different age groups, i.e. 18 to 22 months (the first pregnancy period, 23 to 27 (the first parturition, 28 to 32 (the second pregnancy, and 33 to 42 (the second parturition, respectively. For each age group, a multi-trait animal model was used to estimate variance components and heritabilities of the three traits. The averages of LMA, BFT, and MS measurements across the cows of all age groups were 50.1 cm2, 4.62 mm, and 3.04, respectively and heritability estimates were 0.09, 0.10, and 0.08 for the respective traits. However, when the data were analyzed in different age groups, heritability estimates of LMA and BFT were 0.24 and 0.47, respectively, for the cows of 18 to 22 months of age, and 0.21 for MS in the 28 to 32 months old cows. When the cows of all age groups were used, the estimates of genetic (phenotypic correlations were 0.43 (0.35, −0.06 (0.34 and 0.21 (0.32 between LMA and BFT, LMA and MS, and BFT and MS, respectively. However, in the cow age group between 28 and 32 (18 and 22 months, the estimates of genetic (phenotypic correlations were 0.05 (0.29, −0.15 (0.24 and 0.38 (0.24, for the respective pairs of traits. These results suggest that genetic, environmental, and phenotypic variations differ depending on cow age, such that care must be taken when ultrasound measurements are applied to selection of cows for meat quality.

  10. Ages of Globular Clusters from HIPPARCOS Parallaxes of Local Subdwarfs

    Science.gov (United States)

    Gratton, Raffaele G.; Fusi Pecci, Flavio; Carretta, Eugenio; Clementini, Gisella; Corsi, Carlo E.; Lattanzi, Mario

    1997-12-01

    We report here initial but strongly conclusive results for absolute ages of Galactic globular clusters (GGCs). This study is based on high-precision trigonometric parallaxes from the HIPPARCOS satellite coupled with accurate metal abundances ([Fe/H], [O/Fe], and [α/Fe]) from high-resolution spectroscopy for a sample of about thirty subdwarfs. Systematic effects due to star selection (Lutz-Kelker corrections to parallaxes) and the possible presence of undetected binaries in the sample of bona fide single stars are examined, and appropriate corrections are estimated. They are found to be small for our sample. The new data allow us to reliably define the absolute location of the main sequence (MS) as a function of metallicity. These results are then used to derive distances and ages for a carefully selected sample of nine globular clusters having metallicities determined from high-dispersion spectra of individual giants according to a procedure totally consistent with that used for the field subdwarfs. Very precise and homogeneous reddening values have also been independently determined for these clusters. Random errors for our distance moduli are +/-0.08 mag, and systematic errors are likely of the same order of magnitude. These very accurate distances allow us to derive ages with internal errors of ~12% (+/-1.5 Gyr). The main results are: 1. HIPPARCOS parallaxes are smaller than corresponding ground-based measurements, leading, in turn, to longer distance moduli (~0.2 mag) and younger ages (~2.8 Gyr). 2. The distance to NGC 6752 derived from our MS fitting is consistent with that determined using the white dwarf cooling sequence. 3. The relation between the zero-age HB (ZAHB) absolute magnitude and metallicity for the nine program clusters is MV(ZAHB)=(0.22+/-0.09)([Fe/H]+1.5)+(0.49+/-0.04) . This relation is fairly consistent with some of the most recent theoretical models. Within quoted errors, the slope is in agreement with that given by the Baade-Wesselink (BW

  11. Age estimation by an analysis of spheno-occipital synchondrosis using cone-beam computed tomography.

    Science.gov (United States)

    Sinanoglu, Alper; Kocasarac, Husniye Demirturk; Noujeim, Marcel

    2016-01-01

    The spheno-occipital synchondrosis has a relatively late ossification in comparison with other cranial base synchondroses, which makes it a point of interest for forensic age determination studies. The purpose of the present study was to evaluate the reliability of spheno-occipital synchondrosis development in age determination in a Turkish population and to evaluate the reproducibility and reliability of cone beam computed tomography (CBCT) in an evaluation of the fusion stages of spheno-occipital synchondrosis. CBCT mid-sagittal images of 238 (90 males and 148 females) patients between the ages of 7 and 25, with a mean age of 15.45±0.26 and 16.43±0.37, respectively, were examined by three Oral and Maxillofacial Radiologists who evaluated the degree of synchondrosis fusion using a four-stage system. A reevaluation of 50 cases was conducted for intraobserver assessment. Multiple statistical analyses were used to assess the correlation between age and the fusion stage, to compare gender and age according to stages, and to evaluate the inter- and intraobserver agreement. The mean ages for complete fusion (Stage 3) were 18 and 20 for females and males, respectively. The interobserver agreement ranged between substantial and perfect, while the intraobserver agreement was substantial for all three observers. Based on these results, CBCT, when available, might be the method of choice for age estimation using the spheno-occipital synchondrosis fusion stages. Evaluating spheno-occipital synchondrosis has a value for age estimation around the age of 18 years, which affects the legal decisions in Turkey. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  12. Evaluation of the absolute regional temperature potential

    Directory of Open Access Journals (Sweden)

    D. T. Shindell

    2012-09-01

    Full Text Available The Absolute Regional Temperature Potential (ARTP is one of the few climate metrics that provides estimates of impacts at a sub-global scale. The ARTP presented here gives the time-dependent temperature response in four latitude bands (90–28° S, 28° S–28° N, 28–60° N and 60–90° N as a function of emissions based on the forcing in those bands caused by the emissions. It is based on a large set of simulations performed with a single atmosphere-ocean climate model to derive regional forcing/response relationships. Here I evaluate the robustness of those relationships using the forcing/response portion of the ARTP to estimate regional temperature responses to the historic aerosol forcing in three independent climate models. These ARTP results are in good accord with the actual responses in those models. Nearly all ARTP estimates fall within ±20% of the actual responses, though there are some exceptions for 90–28° S and the Arctic, and in the latter the ARTP may vary with forcing agent. However, for the tropics and the Northern Hemisphere mid-latitudes in particular, the ±20% range appears to be roughly consistent with the 95% confidence interval. Land areas within these two bands respond 39–45% and 9–39% more than the latitude band as a whole. The ARTP, presented here in a slightly revised form, thus appears to provide a relatively robust estimate for the responses of large-scale latitude bands and land areas within those bands to inhomogeneous radiative forcing and thus potentially to emissions as well. Hence this metric could allow rapid evaluation of the effects of emissions policies at a finer scale than global metrics without requiring use of a full climate model.

  13. COMPARISON OF AGE ESTIMATES FROM VARIOUS HARD PARTS FOR REDFIN PERCH, Percafluviatilis, IN TASMANIA

    Directory of Open Access Journals (Sweden)

    Irwan Jatmiko

    2013-06-01

    Full Text Available Whole otoliths, sectioned otoliths, scales and vertebrae were used to select the most suitable for age determination of redfin perch, Percafluviatilis. Redfin perch were sampled from Trevallyn Lake and Brushy Lagoon using fyke nets, gillnets, electrofishing and rod and line angling. Age estimates were assessed for comparison between readings and among structures. One-wayANOVA of readability scores highlighted that sectioned otolith was the most obvious compare to other hard parts. Sectioned otoliths also showed the highest (93.9% agreement between readings, followed by vertebrae (68.7, scales (38.8 and whole otoliths (29.9. Furthermore, there were no significantly different (p>0.05 between first and second readings from sectioned otolith and vertebrae but significantly different (p <0.05 to those from scales and whole otoliths. When sectioned otoliths’ ages were compared with other structures, vertebrae showed the highest (47.6% agreement to those followed by scales (25.2% and whole otoliths (20.4%. Age estimates from sectioned otoliths were significantly different (p<0.05 to the values obtained from vertebrae, scales and whole otoliths.This finding demonstrated that sectioned otoliths are the best hard part for age determination for redfin perch in Tasmania.

  14. Age group estimation in free-ranging African elephants based on acoustic cues of low-frequency rumbles

    OpenAIRE

    Stoeger, Angela S.; Zeppelzauer, Matthias; Baotic, Anton

    2014-01-01

    Animal vocal signals are increasingly used to monitor wildlife populations and to obtain estimates of species occurrence and abundance. In the future, acoustic monitoring should function not only to detect animals, but also to extract detailed information about populations by discriminating sexes, age groups, social or kin groups, and potentially individuals. Here we show that it is possible to estimate age groups of African elephants (Loxodonta africana) based on acoustic parameters extracte...

  15. Prevalence of absolute pitch: a comparison between Japanese and Polish music students.

    Science.gov (United States)

    Miyazaki, Ken'ichi; Makomaska, Sylwia; Rakowski, Andrzej

    2012-11-01

    Comparable large-scale surveys including an on-site pitch-naming test were conducted with music students in Japan and Poland to obtain more convincing estimates of the prevalence of absolute pitch (AP) and examine how musical experience relates to AP. Participants with accurate AP (95% correct identification) accounted for 30% of the Japanese music students, but only 7% of the Polish music students. This difference in the performance of pitch naming was related to the difference in musical experience. Participants with AP had begun music training at an earlier age (6 years or earlier), and the average year of commencement of musical training was more than 2 years earlier for the Japanese music students than for the Polish students. The percentage of participants who had received early piano lessons was 94% for the Japanese musically trained students but was 72% for the Polish music students. Approximately one-third of the Japanese musically trained students had attended the Yamaha Music School, where lessons on piano or electric organ were given to preschool children in parallel with fixed-do solfège singing training. Such early music instruction was not as common in Poland. The relationship of AP with early music training is discussed.

  16. Development and validation of risk prediction equations to estimate survival in patients with colorectal cancer: cohort study

    OpenAIRE

    Hippisley-Cox, Julia; Coupland, Carol

    2017-01-01

    Objective: To develop and externally validate risk prediction equations to estimate absolute and conditional survival in patients with colorectal cancer. \\ud \\ud Design: Cohort study.\\ud \\ud Setting: General practices in England providing data for the QResearch database linked to the national cancer registry.\\ud \\ud Participants: 44 145 patients aged 15-99 with colorectal cancer from 947 practices to derive the equations. The equations were validated in 15 214 patients with colorectal cancer ...

  17. Absolute instrumental neutron activation analysis at Lawrence Livermore Laboratory

    International Nuclear Information System (INIS)

    Heft, R.E.

    1977-01-01

    The Environmental Science Division at Lawrence Livermore Laboratory has in use a system of absolute Instrumental Neutron Activation Analysis (INAA). Basically, absolute INAA is dependent upon the absolute measurement of the disintegration rates of the nuclides produced by neutron capture. From such disintegration rate data, the amount of the target element present in the irradiated sample is calculated by dividing the observed disintegration rate for each nuclide by the expected value for the disintegration rate per microgram of the target element that produced the nuclide. In absolute INAA, the expected value for disintegration rate per microgram is calculated from nuclear parameters and from measured values of both thermal and epithermal neutron fluxes which were present during irradiation. Absolute INAA does not depend on the concurrent irradiation of elemental standards but does depend on the values for thermal and epithermal neutron capture cross-sections for the target nuclides. A description of the analytical method is presented

  18. Single-grain 40Ar-39Ar ages of glauconies: implications for the geologic time scale and global sea level variations

    Science.gov (United States)

    Smith; Evensen; York; Odin

    1998-03-06

    The mineral series glaucony supplies 40% of the absolute-age database for the geologic time scale of the last 250 million years. However, glauconies have long been suspected of giving young potassium-argon ages on bulk samples. Laser-probe argon-argon dating shows that glaucony populations comprise grains with a wide range of ages, suggesting a period of genesis several times longer ( approximately 5 million years) than previously thought. An estimate of the age of their enclosing sediments (and therefore of time scale boundaries) is given by the oldest nonrelict grains in the glaucony populations, whereas the formation times of the younger grains appear to be modulated by global sea level.

  19. Estimated inventory of plutonium and uranium radionuclides for vegetation in aged fallout areas

    International Nuclear Information System (INIS)

    Romney, E.M.; Wallace, A.; Kinnear, J.; Gilbert, R.O.

    1977-01-01

    Data are presented pertinent to the contamination of vegetation by plutonium and other radionuclides in aged fallout areas on the Nevada Test Site (NTS) and the Tonopah Test Range (TTR). The standing biomass of vegetation estimated by nondestructive dimensional methods varied from about 200 to 600 g/m 2 for the different fallout areas. Estimated inventories of 238 Pu, 239 Pu, 240 Pu, and 235 U in plants and their biological effects are discussed

  20. Assessment of MRI-Based Automated Fetal Cerebral Cortical Folding Measures in Prediction of Gestational Age in the Third Trimester.

    Science.gov (United States)

    Wu, J; Awate, S P; Licht, D J; Clouchoux, C; du Plessis, A J; Avants, B B; Vossough, A; Gee, J C; Limperopoulos, C

    2015-07-01

    Traditional methods of dating a pregnancy based on history or sonographic assessment have a large variation in the third trimester. We aimed to assess the ability of various quantitative measures of brain cortical folding on MR imaging in determining fetal gestational age in the third trimester. We evaluated 8 different quantitative cortical folding measures to predict gestational age in 33 healthy fetuses by using T2-weighted fetal MR imaging. We compared the accuracy of the prediction of gestational age by these cortical folding measures with the accuracy of prediction by brain volume measurement and by a previously reported semiquantitative visual scale of brain maturity. Regression models were constructed, and measurement biases and variances were determined via a cross-validation procedure. The cortical folding measures are accurate in the estimation and prediction of gestational age (mean of the absolute error, 0.43 ± 0.45 weeks) and perform better than (P = .024) brain volume (mean of the absolute error, 0.72 ± 0.61 weeks) or sonography measures (SDs approximately 1.5 weeks, as reported in literature). Prediction accuracy is comparable with that of the semiquantitative visual assessment score (mean, 0.57 ± 0.41 weeks). Quantitative cortical folding measures such as global average curvedness can be an accurate and reliable estimator of gestational age and brain maturity for healthy fetuses in the third trimester and have the potential to be an indicator of brain-growth delays for at-risk fetuses and preterm neonates. © 2015 by American Journal of Neuroradiology.

  1. Estimation of submarine mass failure probability from a sequence of deposits with age dates

    Science.gov (United States)

    Geist, Eric L.; Chaytor, Jason D.; Parsons, Thomas E.; ten Brink, Uri S.

    2013-01-01

    The empirical probability of submarine mass failure is quantified from a sequence of dated mass-transport deposits. Several different techniques are described to estimate the parameters for a suite of candidate probability models. The techniques, previously developed for analyzing paleoseismic data, include maximum likelihood and Type II (Bayesian) maximum likelihood methods derived from renewal process theory and Monte Carlo methods. The estimated mean return time from these methods, unlike estimates from a simple arithmetic mean of the center age dates and standard likelihood methods, includes the effects of age-dating uncertainty and of open time intervals before the first and after the last event. The likelihood techniques are evaluated using Akaike’s Information Criterion (AIC) and Akaike’s Bayesian Information Criterion (ABIC) to select the optimal model. The techniques are applied to mass transport deposits recorded in two Integrated Ocean Drilling Program (IODP) drill sites located in the Ursa Basin, northern Gulf of Mexico. Dates of the deposits were constrained by regional bio- and magnetostratigraphy from a previous study. Results of the analysis indicate that submarine mass failures in this location occur primarily according to a Poisson process in which failures are independent and return times follow an exponential distribution. However, some of the model results suggest that submarine mass failures may occur quasiperiodically at one of the sites (U1324). The suite of techniques described in this study provides quantitative probability estimates of submarine mass failure occurrence, for any number of deposits and age uncertainty distributions.

  2. Estimation of fracture toughness of cast stainless steels during thermal aging in LWR systems

    International Nuclear Information System (INIS)

    Chopra, O.K.

    1991-06-01

    A procedure and correlations are presented for predicting the change in fracture toughness of cast stainless steel components due to thermal aging during service in light water rectors (LWRs) at 280--330 degrees C (535--625 degrees F). The fracture toughness J-R curve and Charpy-impact energy of aged cast stainless steels are estimated from known mineral in formation. Fracture toughness of a specific cast stainless steel is estimated from the extent and kinetics of thermal embrittlement. The extent of thermal embrittlement is characterized by the room-temperature ''normalized'' Charpy-impact energy. A correlation for the extent of embrittlement at ''saturation,'' i.e., the minimum impact energy that would be achieved for the material after long-term aging, is given in terms of a material parameter, Φ, which is determined from the chemical composition. The fracture toughness J-R curve for the material is then obtained from correlations between room-temperature Charpy-impact energy and fracture toughness parameters. Fracture toughness as a function of time and temperature of reactor service is estimated from the kinetics of thermal embrittlement, which is determined from chemical composition. A common ''lower-bound'' J-R curve for cast stainless steels with unknown chemical composition is also defined for a given material specification, ferrite content, and temperature. Examples for estimating impact strength and fracture toughness of cast stainless steel components during reactor service are describes. 24 refs., 39 figs., 2 tabs

  3. Estimation of fracture toughness of cast stainless steels during thermal aging in LWR systems

    Energy Technology Data Exchange (ETDEWEB)

    Chopra, O.K. (Argonne National Lab., IL (USA))

    1991-06-01

    A procedure and correlations are presented for predicting the change in fracture toughness of cast stainless steel components due to thermal aging during service in light water rectors (LWRs) at 280--330{degrees}C (535--625{degrees}F). The fracture toughness J-R curve and Charpy-impact energy of aged cast stainless steels are estimated from known mineral in formation. Fracture toughness of a specific cast stainless steel is estimated from the extent and kinetics of thermal embrittlement. The extent of thermal embrittlement is characterized by the room-temperature normalized'' Charpy-impact energy. A correlation for the extent of embrittlement at saturation,'' i.e., the minimum impact energy that would be achieved for the material after long-term aging, is given in terms of a material parameter, {Phi}, which is determined from the chemical composition. The fracture toughness J-R curve for the material is then obtained from correlations between room-temperature Charpy-impact energy and fracture toughness parameters. Fracture toughness as a function of time and temperature of reactor service is estimated from the kinetics of thermal embrittlement, which is determined from chemical composition. A common lower-bound'' J-R curve for cast stainless steels with unknown chemical composition is also defined for a given material specification, ferrite content, and temperature. Examples for estimating impact strength and fracture toughness of cast stainless steel components during reactor service are describes. 24 refs., 39 figs., 2 tabs.

  4. Absolute calibration of SARAL/AltiKa in Kavaratti during its initial calibration-validation phase

    Digital Repository Service at National Institute of Oceanography (India)

    Babu, K.N.; Shukla, A.K.; Suchandra, A.B.; ArunKumar, S.V.V.; Bonnefond, P.; Testut, L.; Mehra, P.; Laurain, O.

    globally distributed region will offer assessment of the altimetry system, and allow us to check in specific conditions leading to different estimation of absolute bias of the instrument (Shum et al. 2003). In collaboration with National Institute... of Oceanography (NIO), Goa, Space Applica- tions Centre–Indian Space Research Organisation (SAC-ISRO) established a calibration- verification site in Kavaratti. This site offers a number of advantages as a calibration site for altimeters. Having very small land...

  5. Absolute-magnitude distributions of supernovae

    Energy Technology Data Exchange (ETDEWEB)

    Richardson, Dean; Wright, John [Department of Physics, Xavier University of Louisiana, New Orleans, LA 70125 (United States); Jenkins III, Robert L. [Applied Physics Department, Richard Stockton College, Galloway, NJ 08205 (United States); Maddox, Larry, E-mail: drichar7@xula.edu [Department of Chemistry and Physics, Southeastern Louisiana University, Hammond, LA 70402 (United States)

    2014-05-01

    The absolute-magnitude distributions of seven supernova (SN) types are presented. The data used here were primarily taken from the Asiago Supernova Catalogue, but were supplemented with additional data. We accounted for both foreground and host-galaxy extinction. A bootstrap method is used to correct the samples for Malmquist bias. Separately, we generate volume-limited samples, restricted to events within 100 Mpc. We find that the superluminous events (M{sub B} < –21) make up only about 0.1% of all SNe in the bias-corrected sample. The subluminous events (M{sub B} > –15) make up about 3%. The normal Ia distribution was the brightest with a mean absolute blue magnitude of –19.25. The IIP distribution was the dimmest at –16.75.

  6. Non-working nurses in Japan: estimated size and its age-cohort characteristics.

    Science.gov (United States)

    Nakata, Yoshifumi; Miyazaki, Satoru

    2008-12-01

    This paper aims to forecast the total number of non-working nursing staff in Japan both overall and in terms of separate age groups for assistant nurses and fully qualified nurses. This also examines policy implications of those forecasts. Although the existence of around 550,000 of non-working nursing staff has been announced, the actual number of non-working nurses is not so clear that we might make errors in making policy to meet nurse workforce demand and supply in Japan. Estimations by integrating various data on the quantitative characteristics of non-working nursing staff were carried out. Considering the length and the type of education or training in referred four nursing positions; registered nurses, assistant nurses, public health nurses and midwives, we first estimated the number of students who completed a full course. And then multiplying by the ratio for gender and age classifications at the time of entry into courses, the number of those who obtained licenses was estimated. The number of non-working nurses was estimated at 100,000 higher than those in 2005 by government. Looking at age group, it is also possible to see a strong reflection of an employment pattern that follows the life cycle of female workers. Further analysis of life cycle effects and cohort effects proved the effect of life cycles even when subtracting the differences between the working behaviours of different generations. Our findings strongly suggest the need to provide an urgent policy that workplace conditions can be created in which a balance between work and family is achievable. Moreover, to empower clinical activity, we also believe there is an urgent need to reexamine the overall career vision for assistant nurses including in terms of compensation. Relevance to clinical practice. Our findings strongly suggests that consideration for work-life balance of nursing staff; particularly, female staff is all the more important to provide a stable quality care.

  7. Microelements in fossil bones and the estimation of age

    International Nuclear Information System (INIS)

    Besliu, C.; Olariu, A.; Popescu, I.; Badica, Th.

    1993-01-01

    Neutron activation analysis was used to determine microelements fossil bones and the correlation was found between some elements and the C-14 estimated age of the bones. Fluorine, uranium and manganese content in the bones structure increases with the time elapsed, during fossilization. This means that measurable concentrations of these elements and known environmental conditions could provide a relative dating tool of bones beyond the 70 ky radiocarbon limit, for paleolithic archaeology. Sodium, scandium, iron, and zinc have been also determined in fossil bones, but a relation with the increasing antiquity of the fossil has been observed. (Author)

  8. [Problems associated with age estimation of underage persons who appear in child pornography materials].

    Science.gov (United States)

    Łabecka, Marzena; Lorkiewicz-Muszyńska, Dorota; Jarzabek-Bielecka, Grazyna

    2011-01-01

    Among opinions issued by the Forensic Medicine Department, Medical Science University in Poznan, in the last six years, there are opinions concerning age estimation in child pornography materials. The issue subject to research is indicating persons under the age of 15 years in pornographic materials, since possession of pornographic materials featuring underage persons is considered a crime and is subject to article 202 of the Penal Code. The estimation of the age of teenagers based on secondary and tertiary sexual characteristics is increasingly more difficult and the available data in professional literature regarding the standard time of development differ among various authors of such studies. In the report, an attempt has been made at determining the agreement regarding different characteristics in the data included in the Tanner's scale, which has been modified to accommodate the research done on persons registered by electronic means. The modified scale, which up to now has been used in research of registered subjects in classified public prosecutors' materials, has been employed in children seen in a pediatric outpatient department. The goal has been a comparison of the outcome of the research to prove its usefulness so that in the future, the modified scale could be used as a research tool in estimation of age of persons appearing in pornography materials. medical forms of 205 children seen in a pediatric outpatient department, based on the scale created by the present authors us and later processed using Excel.

  9. Radiologic assessment of third molar tooth and spheno-occipital synchondrosis for age estimation: a multiple regression analysis study.

    Science.gov (United States)

    Demirturk Kocasarac, Husniye; Sinanoglu, Alper; Noujeim, Marcel; Helvacioglu Yigit, Dilek; Baydemir, Canan

    2016-05-01

    For forensic age estimation, radiographic assessment of third molar mineralization is important between 14 and 21 years which coincides with the legal age in most countries. The spheno-occipital synchondrosis (SOS) is an important growth site during development, and its use for age estimation is beneficial when combined with other markers. In this study, we aimed to develop a regression model to estimate and narrow the age range based on the radiologic assessment of third molar and SOS in a Turkish subpopulation. Panoramic radiographs and cone beam CT scans of 349 subjects (182 males, 167 females) with age between 8 and 25 were evaluated. Four-stage system was used to evaluate the fusion degree of SOS, and Demirjian's eight stages of development for calcification for third molars. The Pearson correlation indicated a strong positive relationship between age and third molar calcification for both sexes (r = 0.850 for females, r = 0.839 for males, P < 0.001) and also between age and SOS fusion for females (r = 0.814), but a moderate relationship was found for males (r = 0.599), P < 0.001). Based on the results obtained, an age determination formula using these scores was established.

  10. Absolute cardiovascular risk in a Fiji medical zone.

    Science.gov (United States)

    Gyaneshwar, Rajat; Naidu, Swaran; Raban, Magdalena Z; Naidu, Sheetal; Linhart, Christine; Morrell, Stephen; Tukana, Isimeli; Taylor, Richard

    2016-02-09

    The population of Fiji has experienced emergence of non-communicable disease (NCD) and a plateau in life expectancy over the past 20 years. A mini-STEPS survey (n = 2765) was conducted in Viseisei in Western Fiji to assess NCD risk factors (RFs) in i-Taukei (Melanesians) and those of Indian descent aged 25-64 years (response 73 %). Hypertension (HT) was defined as systolic blood pressure (BP) ≥140 mmHg or diastolic BP ≥90 mmHg or on medication for HT; type 2 diabetes mellitus (T2DM) as fasting plasma glucose ≥7.0 mmol/L or on medication for T2DM; and obesity as a body mass index (kilograms/height(metres)(2)) ≥30. Data were age-adjusted to 2007 Fiji Census. Associations between RFs and ethnicity/education were investigated. Comparisons with Fiji STEPS surveys were undertaken, and the absolute risk of a cardiovascular disease (CVD) event/death in 10 years was estimated from multiple RF charts. NCD/RFs increased with age except excessive alcohol intake and daily smoking (women) which declined. Daily smoking was higher in men 33 % (95 % confidence interval: 31-36) than women 14 % (12-116); women were more obese 40 % (37-43) than men 23 % (20-26); HT was similar in men 37 % (34-40) and women 34 % (31-36), as was T2DM in men 15 % (13-17) and women 17 % (15-19). i-Taukei men had an odds ratio (OR) of 0.41 (0.28-0.58) for T2DM compared to Indians (1.00); and i-Taukei (both sexes) had a higher OR for obesity and low fruit/vegetable intake, daily smoking, excessive alcohol intake and HT in females. Increasing education correlated with lesser smoking, but with higher obesity and lower fruit/vegetable intake. Compared to the 2011 Fiji STEPS survey, no significant differences were evident in obesity, HT or T2DM prevalences. The proportion (40-64 years) classified at high or very high risk (≥20 %) of a CVD event/death (over 10 years) based on multiple RFs was 8.3 % for men (8.1 % i-Taukei, 8.5 % Indian), and 6.7 % for women (7.9 % i-Taukei, 6.0 % Indian). The results

  11. Introduction to variance estimation

    CERN Document Server

    Wolter, Kirk M

    2007-01-01

    We live in the information age. Statistical surveys are used every day to determine or evaluate public policy and to make important business decisions. Correct methods for computing the precision of the survey data and for making inferences to the target population are absolutely essential to sound decision making. Now in its second edition, Introduction to Variance Estimation has for more than twenty years provided the definitive account of the theory and methods for correct precision calculations and inference, including examples of modern, complex surveys in which the methods have been used successfully. The book provides instruction on the methods that are vital to data-driven decision making in business, government, and academe. It will appeal to survey statisticians and other scientists engaged in the planning and conduct of survey research, and to those analyzing survey data and charged with extracting compelling information from such data. It will appeal to graduate students and university faculty who...

  12. Early estimation of epicenter seismic intensities according to co-seismic deformation

    OpenAIRE

    Weidong, Li; Chaojun, Zhang; Dahui, Li; Jiayong, He; Huizhong, Chen; Lomnitz, Cinna

    2010-01-01

    The absolute fault displacement in co-seismic deformation is derived assuming that location, depth, faulting mechanism and magnitude of the earthquake are known. The 2008 Wenchuan earthquake (M8.0) is used as an example to determine the distribution of seismic intensities using absolute displacement and a crustal model. We fnd that an early prediction of the distribution of seismic intensities after a large earthquake may be performed from the estimated absolute co-seismic displacements using...

  13. Estimating demographic contributions to effective population size in an age-structured wild population experiencing environmental and demographic stochasticity.

    Science.gov (United States)

    Trask, Amanda E; Bignal, Eric M; McCracken, Davy I; Piertney, Stuart B; Reid, Jane M

    2017-09-01

    A population's effective size (N e ) is a key parameter that shapes rates of inbreeding and loss of genetic diversity, thereby influencing evolutionary processes and population viability. However, estimating N e , and identifying key demographic mechanisms that underlie the N e to census population size (N) ratio, remains challenging, especially for small populations with overlapping generations and substantial environmental and demographic stochasticity and hence dynamic age-structure. A sophisticated demographic method of estimating N e /N, which uses Fisher's reproductive value to account for dynamic age-structure, has been formulated. However, this method requires detailed individual- and population-level data on sex- and age-specific reproduction and survival, and has rarely been implemented. Here, we use the reproductive value method and detailed demographic data to estimate N e /N for a small and apparently isolated red-billed chough (Pyrrhocorax pyrrhocorax) population of high conservation concern. We additionally calculated two single-sample molecular genetic estimates of N e to corroborate the demographic estimate and examine evidence for unobserved immigration and gene flow. The demographic estimate of N e /N was 0.21, reflecting a high total demographic variance (σ2dg) of 0.71. Females and males made similar overall contributions to σ2dg. However, contributions varied among sex-age classes, with greater contributions from 3 year-old females than males, but greater contributions from ≥5 year-old males than females. The demographic estimate of N e was ~30, suggesting that rates of increase of inbreeding and loss of genetic variation per generation will be relatively high. Molecular genetic estimates of N e computed from linkage disequilibrium and approximate Bayesian computation were approximately 50 and 30, respectively, providing no evidence of substantial unobserved immigration which could bias demographic estimates of N e . Our analyses identify

  14. Estimation of natural age of menopause in Iranian women: A meta-analysis study

    Directory of Open Access Journals (Sweden)

    Abdolreza Rajaeefard

    2011-10-01

    Full Text Available Introduction: The mean age of menopause have been reported at the age of 51 in the world and regarding the increase in life expectancy in many countries more than a third of the life time of women i s in menopause period. The importance of menopause is due to its relationship with various diseases and quality of life. The present study was conducted to estimate the average natural age of menopause in women based on a meta-analysis study. Material and Methods: In a meta-analysis study on all the existing articles in the natural age o f menopause in Iran, 21 articles were selected based on inclusion criteria. Begg and Egger tests fo r publication bias and Cochrane test were used to determine the heterogeneity among samples. ???? estimate of mean calculated based on Random effect model in Stata11 software. Results: The publication bias assumption was rejected by Begg and Egger tests with significant value s equal to 0.174 and 0.446 respectively. There was a heterogeneity among samples (Q=4626.3, df=20 , P<0.001. So based on random effect model the mean age of menopause was calculated as 48.183 with 95 % CI=47.457-48.91. Conclusion: The average age of natural menopause in Iranian women is favorable to some places of Middle East, but is less compared with developed countries and the world mean. Because of the importance of this period in women, educational programs seem to be necessary.

  15. An examination of healthy aging across a conceptual continuum: prevalence estimates, demographic patterns, and validity.

    Science.gov (United States)

    McLaughlin, Sara J; Jette, Alan M; Connell, Cathleen M

    2012-06-01

    Although the notion of healthy aging has gained wide acceptance in gerontology, measuring the phenomenon is challenging. Guided by a prominent conceptualization of healthy aging, we examined how shifting from a more to less stringent definition of healthy aging influences prevalence estimates, demographic patterns, and validity. Data are from adults aged 65 years and older who participated in the Health and Retirement Study. We examined four operational definitions of healthy aging. For each, we calculated prevalence estimates and examined the odds of healthy aging by age, education, gender, and race-ethnicity in 2006. We also examined the association between healthy aging and both self-rated health and death. Across definitions, the prevalence of healthy aging ranged from 3.3% to 35.5%. For all definitions, those classified as experiencing healthy aging had lower odds of fair or poor self-rated health and death over an 8-year period. The odds of being classified as "healthy" were lower among those of advanced age, those with less education, and women than for their corresponding counterparts across all definitions. Moving across the conceptual continuum--from a more to less rigid definition of healthy aging--markedly increases the measured prevalence of healthy aging. Importantly, results suggest that all examined definitions identified a subgroup of older adults who had substantially lower odds of reporting fair or poor health and dying over an 8-year period, providing evidence of the validity of our definitions. Conceptualizations that emphasize symptomatic disease and functional health may be particularly useful for public health purposes.

  16. Planck absolute entropy of a rotating BTZ black hole

    Science.gov (United States)

    Riaz, S. M. Jawwad

    2018-04-01

    In this paper, the Planck absolute entropy and the Bekenstein-Smarr formula of the rotating Banados-Teitelboim-Zanelli (BTZ) black hole are presented via a complex thermodynamical system contributed by its inner and outer horizons. The redefined entropy approaches zero as the temperature of the rotating BTZ black hole tends to absolute zero, satisfying the Nernst formulation of a black hole. Hence, it can be regarded as the Planck absolute entropy of the rotating BTZ black hole.

  17. Absolute nuclear material assay using count distribution (LAMBDA) space

    Science.gov (United States)

    Prasad, Manoj K [Pleasanton, CA; Snyderman, Neal J [Berkeley, CA; Rowland, Mark S [Alamo, CA

    2012-06-05

    A method of absolute nuclear material assay of an unknown source comprising counting neutrons from the unknown source and providing an absolute nuclear material assay utilizing a model to optimally compare to the measured count distributions. In one embodiment, the step of providing an absolute nuclear material assay comprises utilizing a random sampling of analytically computed fission chain distributions to generate a continuous time-evolving sequence of event-counts by spreading the fission chain distribution in time.

  18. Comparison between Greulich-Pyle and Girdany-Golden methods for estimating skeletal age of children in Pakistan.

    Science.gov (United States)

    Awais, Muhammad; Nadeem, Naila; Husen, Yousuf; Rehman, Abdul; Beg, Madiha; Khattak, Yasir Jamil

    2014-12-01

    To compare Greulich-Pyle (GP) and Girdany-Golden (GG) methods for estimation of Skeletal Age (SA) in children referred to a tertiary care hospital in Karachi, Pakistan. Cross-sectional study. Department of Radiology, The Aga Khan University Hospital, Karachi, Pakistan, from July 2010 to June 2012. Children up to the age of 18 years, who had undergone X-ray for the evaluation of trauma were included. Each X-ray was interpreted using both methods by two consultant paediatric radiologists having at least 10 years experience, who were blinded to the actual Chronologic Age (CA) of children. A total of 283 children were included. No significant difference was noted in mean SA estimated by GP method and mean CA for female children (p=0.695). However, a significant difference was noted between mean CA and mean SA by GG method for females (p=0.011). For males, there was a significant difference between mean CA and mean SA estimated by both GP and GG methods. A stronger correlation was found between CA and SA estimated by GP method (r=0.943 for girls, r=0.915 for boys) as compared to GG method (r=0.909 for girls, r=0.865 for boys) respectively. Bland- Altman analysis also revealed that the two methods cannot be used interchangeably. Excellent correlation was seen between the two readers for both GP and GG methods. There was no additional benefit of using GP and GG methods simultaneously over using GP method alone. Moreover, although GP was reliable in estimating SA in girls, it was unable to accurately assess SA in boys. Therefore, it would be ideal to develop indigenous standards of bone age estimation based on a representative sample of healthy native children.

  19. Comparison between greulich-pyle and girdany-golden methods for estimating skeletal age of children in pakistan

    International Nuclear Information System (INIS)

    Awais, M.; Nadeem, N.; Rehman, A.

    2014-01-01

    Objective: To compare Greulich-Pyle (GP) and Girdany-Golden (GG) methods for estimation of Skeletal Age (SA) in children referred to a tertiary care hospital in Karachi, Pakistan. Study Design: Cross-sectional study. Place and Duration of Study: Department of Radiology, The Aga Khan University Hospital, Karachi, Pakistan, from July 2010 to June 2012. Methodology: Children up to the age of 18 years, who had undergone X-ray for the evaluation of trauma were included. Each X-ray was interpreted using both methods by two consultant paediatric radiologists having at least 10 years experience, who were blinded to the actual Chronologic Age (CA) of children. Results: A total of 283 children were included. No significant difference was noted in mean SA estimated by GP method and mean CA for female children (p=0.695). However, a significant difference was noted between mean CA and mean SA by GG method for females (p=0.011). For males, there was a significant difference between mean CA and mean SA estimated by both GP and GG methods. A stronger correlation was found between CA and SA estimated by GP method (r=0.943 for girls, r=0.915 for boys) as compared to GG method (r=0.909 for girls, r=0.865 for boys) respectively. Bland- Altman analysis also revealed that the two methods cannot be used interchangeably. Excellent correlation was seen between the two readers for both GP and GG methods. Conclusion: There was no additional benefit of using GP and GG methods simultaneously over using GP method alone. Moreover, although GP was reliable in estimating SA in girls, it was unable to accurately assess SA in boys. Therefore, it would be ideal to develop indigenous standards of bone age estimation based on a representative sample of healthy native children. (author)

  20. Age difference in deposition of plutonium in organs of rats and the estimation of distribution in humans

    Energy Technology Data Exchange (ETDEWEB)

    Fukuda, Satoshi; Iida, Haruzo [National Inst. of Radiological Sciences, Chiba (Japan)

    2000-05-01

    Differences in plutonium distribution in various organs, particularly the bones, of rats injected at different ages were examined in order to aid in estimating plutonium distribution in humans. Comparisons were made between rats and humans based on the bone histomorphometric and mineral density data. Male and female rats of three ages (3, 12, and 24 months old), respectively, received an injection of plutonium nitrate by two dose modalities; a fixed amount of plutonium without regard to age, sex, or body weight; per g of body weight. The rats were killed 2 weeks after the injection of plutonium. The amounts of plutonium deposited in the organs varied without regard to the body or organ weight; those in the skeleton increased from 3 to 12 months, reaching a peak at 12 months, but then decreased, along with the age-related changes in the bone surface, volume, and mineral density. Those in the liver, spleen and kidney decreased despite the body weight gain with age in both sexes. Age-related differences in the deposition of plutonium in humans were estimated based on the bone data characteristics obtained from the histomorphometry and bone mineral density for corresponding of ages between rats and humans. The results indicate that age is the most important factor in estimating the distribution of plutonium deposition in the early period after plutonium exposure, and that body or organ weight is not always a useful indicator, particularly in the aged. (author)

  1. On the age and metallicity estimation of spiral galaxies using optical and near-infrared photometry

    NARCIS (Netherlands)

    Lee, Hyun-Chul; Worthey, Guy; Trager, Scott C.; Faber, S. M.

    2007-01-01

    In integrated light, some color-color diagrams that use optical and near-infrared photometry show surprisingly orthogonal grids as age and metallicity are varied, and they are coming into common usage for estimating the average age and metallicity of spiral galaxies. In this paper we reconstruct

  2. MAGNETO-CONVECTION AND LITHIUM AGE ESTIMATES OF THE β PICTORIS MOVING GROUP

    International Nuclear Information System (INIS)

    Macdonald, J.; Mullan, D. J.

    2010-01-01

    Although the means of the ages of stars in young groups determined from Li depletion often agree with mean ages determined from Hertzsprung-Russell (H-R) diagram isochrones, there are often statistically significant differences in the ages of individual stars determined by the two methods. We find that inclusion of the effects of inhibition of convection due to the presence of magnetic fields leads to consistent ages for the individual stars. We illustrate how age consistency arises by applying our results to the β Pictoris moving group (BPMG). We find that, although magnetic inhibition of convection leads to increased ages from the H-R diagram isochrones for all stars, Li ages are decreased for fully convective M stars and increased for stars with radiative cores. Our consistent age determination for BPMG of 40 Myr is larger than previous determinations by a factor of about two. We have also considered models in which the mixing length ratio is adjusted to give consistent ages. We find that our magneto-convection models, which give quantitative estimates of magnetic field strength, provide a viable alternative to models in which the effects of magnetic fields (and other processes) are accounted for by reducing the mixing length ratio.

  3. Changes in mortality inequalities across occupations in Japan: a national register based study of absolute and relative measures, 1980-2010.

    Science.gov (United States)

    Tanaka, Hirokazu; Toyokawa, Satoshi; Tamiya, Nanako; Takahashi, Hideto; Noguchi, Haruko; Kobayashi, Yasuki

    2017-09-05

    Changes in mortality inequalities across socioeconomic groups have been a substantial public health concern worldwide. We investigated changes in absolute/relative mortality inequalities across occupations, and the contribution of different diseases to inequalities in tandem with the restructuring of the Japanese economy. Using complete Japanese national death registries from 5 year intervals (1980-2010), all cause and cause specific age standardised mortality rates (ASMR per 100 000 people standardised using the Japanese standard population in 1985, aged 30-59 years) across 12 occupations were computed. Absolute and relative inequalities were measured in ASMR differences (RDs) and ASMR ratios (RRs) among occupations in comparison with manufacturing workers (reference). We also estimated the changing contribution of different diseases by calculating the differences in ASMR change between 1995 and 2010 for occupations and reference. All cause ASMRs tended to decrease in both sexes over the three decades except for male managers (increased by 71% points, 1995-2010). RDs across occupations were reduced for both sexes (civil servants 233.5 to -1.9 for men; sales workers 63.3 to 4.5 for women) but RRs increased for some occupations (professional workers 1.38 to 1.70; service workers 2.35 to 3.73) for men and decreased for women from 1980 to 2010. Male relative inequalities widened among farmer, fishery and service workers, because the percentage declines were smaller in these occupations. Cerebrovascular disease and cancer were the main causes of the decrease in mortality inequalities among sexes but the incidence of suicide increased among men, thereby increasing sex related inequalities. Absolute inequality trends in mortality across occupations decreased in both sexes, while relative inequality trends were heterogeneous in Japan. The main drivers of narrowing and widening mortality inequalities were cerebrovascular disease and suicide, respectively. Future

  4. Tooth coronal index: Key for age estimation on digital panoramic radiographs

    Directory of Open Access Journals (Sweden)

    Ravleen Nagi

    2018-01-01

    Full Text Available Background: Assessment of age through teeth is one of the most reliable and simple method than skeletal remains, to calculate age of an individual. Objectives: The study was carried out with an aim to evaluate reliability of dental age assessment through tooth coronal index (TCI method. Materials and Methods: The digital panoramic radiographs of 100 subjects of Chhattisgarh aged 20–70 years were selected for the study. The measurements were performed on the JPEG images of selected panoramic radiographs by using Adobe Acrobat 7.0 professional software. The height of the crown, i.e., coronal height, and the height of the coronal pulp cavity, i.e., coronal pulp cavity height, of mandibular second premolars and first molars were measured in millimeter (mm and then TCI was calculated for each tooth. Actual age of a subject was compared with TCI of tooth and the acquired data were subjected to Pearson's correlation and unpaired t-tests. Results: Negative correlation was observed between the real age and TCI of mandibular first molar (r = −0.092, P = 0.365 and second premolar (r = −0.168, P = 0.096. Statistically significant difference was observed between real age and TCI for mandibular second premolar and first molar (P = 0.000 by unpaired t-test. Conclusion: TCI has the potential to estimate age of an individual on dental radiographs. It is simple, cost effective than histological methods and can be applied to both living and unknown dead.

  5. Determination of the Absolute Disintegration Rate of Cs-137 sources by the Tracer Method

    Energy Technology Data Exchange (ETDEWEB)

    Hellstroem, S; Brune, D

    1963-07-15

    {sup 137}Cs - sources were absolutely measured by the 'tracer method', with {sup 82}Br as a tracer nuclide and with application of the 4{pi} {beta}-{gamma} coincidence technique. A self-absorption of 6 % was found in sources obtained from a solution with a carrier-content of 400 {mu}g/ml. The precision of the method for the determination of the {beta}-emission rate was estimated to {+-} 1 %. The results were compared with those of other works.

  6. Determination of the Absolute Disintegration Rate of Cs-137 sources by the Tracer Method

    International Nuclear Information System (INIS)

    Hellstroem, S.; Brune, D.

    1963-07-01

    137 Cs - sources were absolutely measured by the 'tracer method', with 82 Br as a tracer nuclide and with application of the 4π β-γ coincidence technique. A self-absorption of 6 % was found in sources obtained from a solution with a carrier-content of 400 μg/ml. The precision of the method for the determination of the β-emission rate was estimated to ± 1 %. The results were compared with those of other works

  7. Estimating loss of Brucella abortus antibodies from age-specific serological data in elk

    Science.gov (United States)

    Benavides, J. A.; Caillaud, D.; Scurlock, B. M.; Maichak, E. J.; Edwards, W.H.; Cross, Paul C.

    2017-01-01

    Serological data are one of the primary sources of information for disease monitoring in wildlife. However, the duration of the seropositive status of exposed individuals is almost always unknown for many free-ranging host species. Directly estimating rates of antibody loss typically requires difficult longitudinal sampling of individuals following seroconversion. Instead, we propose a Bayesian statistical approach linking age and serological data to a mechanistic epidemiological model to infer brucellosis infection, the probability of antibody loss, and recovery rates of elk (Cervus canadensis) in the Greater Yellowstone Ecosystem. We found that seroprevalence declined above the age of ten, with no evidence of disease-induced mortality. The probability of antibody loss was estimated to be 0.70 per year after a five-year period of seropositivity and the basic reproduction number for brucellosis to 2.13. Our results suggest that individuals are unlikely to become re-infected because models with this mechanism were unable to reproduce a significant decline in seroprevalence in older individuals. This study highlights the possible implications of antibody loss, which could bias our estimation of critical epidemiological parameters for wildlife disease management based on serological data.

  8. White blood cell count, absolute neutrophil count, as predictors of hidden bacterial infections in febrile children 1-18 months of age without focus

    International Nuclear Information System (INIS)

    AL-Majali, R.M.

    2004-01-01

    Objectives: To study the relationship between White Blood Cell (WBC), Absolute Neutrophil Count (ANC) in febrile children 1-18 months of age as predictor of bacterial infection, so as to improve our predictability of bacterial infections in emergency room to decrease unnecessary admissions and antibiotic use. Methods: Retrospective review was performed on febrile patients 1-18 months of age that were admitted to hospital between August 2002 and March 2003 on the presumptive diagnosis of fever without focus, Complete septic work up was done for all patients according to local hospital protocol including Complete blood count (CBC), blood culture, urine culture, Chest X-Ray (CXR) and lumbar puncture, Patients who had history of antibiotics use within 48 hours of admission were excluded from the study, History, physical examination, laboratory and radiology data were reviewed. Data about the age, sex, temperature, presence or absence of focal bacterial infection, WBC, ANC, CXR report and body fluid culture results were collected and analyzed. Results: Thirty-four patients were reviewed in this study, Eight patients (23.5%) had bacterial infection: classified as group (2 patchy pneumonia, 3 Urinary tract infection (UTI), 2 meningitis, 1 Occult bacteremia (OB) and 26 patients (76.5%) had no evidence of bacterial infection, classified as group 2, No significant difference was found between the two groups in respect to age, sex, temperature and WBC P>0.05, while there was a significant difference between the two groups in respect to the ANC P = 0.02, also ANC had better sensitivity (78%) and specificity (89%) than WBC (sensitivity 77%, specificity 62%). Conclusion: ANC is a good predictive test for determining bacterial infection in young febrile children without focus, However there is need for other more reliable rapid cost effective measures in dealing with young febrile children at emergency department. (author)

  9. Age estimation by dental developmental stages in children and adolescents in Iceland.

    Science.gov (United States)

    Vidisdottir, Sigridur Rosa; Richter, Svend

    2015-12-01

    Studies have shown that it is necessary to create a database for dental maturity for every population and compare it to others. The present study is the first one for dental development in the Icelandic population the age range being 4-24 years. It will help in forensic dental age estimation and will also help dentists, physicians, anthropologists, archaeologists and other professionals who rely on developmental age assessment in children and adolescents. In this present retrospective cross-sectional study, dental maturity was determined in 1100 Icelandic children and adolescents from orthopantomograms (OPGs). The first 100 were used for a pilot study and the remaining 1000 for the main study. A total of 23 subjects were excluded. The sample consisted of 508 girls and 469 boys from the age of 4-24 years and a dental developmental scoring system was used as a standard for determination of dental maturity stages. A total of 200 OPGs were studied both on the left and right side and the remaining on the right side. Dental maturity was established for all teeth and both genders, when the sample permitted, from the beginning of crown formation to the root apex closure. The Cronbach's Alpha reliability test showed high reliability, R=0.982. Girls in Iceland reach dental maturity root completed (stage 10, Rc) at 17.81 years of age for the maxillary and at 18.47 years for the mandibular teeth. Boys reach dental maturity root completed (stage 10, Rc) at 18.00 years of age in the maxilla and 17.63 in the mandible. There was no significant difference between left and right side (r=0.95-1.00) and there was no gender difference, except in root formation in maxillary and mandibular canines where girls reached root completed earlier than boys. A reliable database has been established in Iceland for tooth development in the age range of 4-24 years, which is compatible with international studies. These results will help forensic odontologists and other professionals to estimate with

  10. ESTIMATION OF AGING EFFECTS OF PILES IN MALAYSIAN OFFSHORE LOCATIONS

    Directory of Open Access Journals (Sweden)

    JERIN M. GEORGE

    2017-04-01

    Full Text Available An increasing demand for extending life and subsequently higher loading requirements of offshore jacket platforms are among the key problems faced by the offshore industry. The Aging effect has been proved to increase the axial capacity of piles, but proper methods to estimate and quantify these effects have not been developed. Borehole data from ten different Malaysian offshore locations have been analysed and they were employed to estimate the setup factor for different locations using AAU method. The setup factors found were used in the Skov and Denver equation to calculate capacity ratios of the offshore piles. The study showed that there will be an average improvement in the axial capacity of offshore piles by 42.2% and 34.9% for clayey and mixed soils respectively after a time equal to the normal design life (25 years of a jacket platform.

  11. Evaluation of Cases Admitted for Age Estimation to Forensic Medicine Department Between 2006 and 2010 Years

    Directory of Open Access Journals (Sweden)

    Ali Yildirim

    2011-06-01

    Conclusion: In conclusion age determination continues to be one of the important issues of forensic medicine. In cases of age determination, more accurate estimates can be accomplished when radiologically determined age is considered in conjunction with clinical findings such as dental, mental, and psychologic development. [J Contemp Med 2011; 1(2.000: 56-61

  12. Estimating Utility

    DEFF Research Database (Denmark)

    Arndt, Channing; Simler, Kenneth R.

    2010-01-01

    A fundamental premise of absolute poverty lines is that they represent the same level of utility through time and space. Disturbingly, a series of recent studies in middle- and low-income economies show that even carefully derived poverty lines rarely satisfy this premise. This article proposes a......, with the current approach tending to systematically overestimate (underestimate) poverty in urban (rural) zones.......A fundamental premise of absolute poverty lines is that they represent the same level of utility through time and space. Disturbingly, a series of recent studies in middle- and low-income economies show that even carefully derived poverty lines rarely satisfy this premise. This article proposes...... an information-theoretic approach to estimating cost-of-basic-needs (CBN) poverty lines that are utility consistent. Applications to date illustrate that utility-consistent poverty measurements derived from the proposed approach and those derived from current CBN best practices often differ substantially...

  13. Approach to Absolute Zero

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 10. Approach to Absolute Zero Below 10 milli-Kelvin. R Srinivasan. Series Article Volume 2 Issue 10 October 1997 pp 8-16. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/002/10/0008-0016 ...

  14. Estimated exposures to perfluorinated compounds in infancy predict attenuated vaccine antibody concentrations at age 5-years

    DEFF Research Database (Denmark)

    Grandjean, Philippe; Heilmann, Carsten; Weihe, Pal

    2017-01-01

    Perfluorinated alkylate substances (PFASs) are highly persistent and may cause immunotoxic effects. PFAS-associated attenuated antibody responses to childhood vaccines may be affected by PFAS exposures during infancy, where breastfeeding adds to PFAS exposures. Of 490 members of a Faroese birth...... cohort, 275 and 349 participated in clinical examinations and provided blood samples at ages 18 months and 5 years. PFAS concentrations were measured at birth and at the clinical examinations. Using information on duration of breastfeeding, serum-PFAS concentration profiles during infancy were estimated......, with decreases by up to about 20% for each two-fold higher exposure, while associations for serum concentrations at ages 18 months and 5 years were weaker. Modeling of serum-PFAS concentration showed levels for age 18 months that were similar to those measured. Concentrations estimated for ages 3 and 6 months...

  15. Tropical dendrochemistry: A novel approach to estimate age and growth from ringless trees

    International Nuclear Information System (INIS)

    Poussart, P.; Myneni, S.; Lanzirotti, A.

    2006-01-01

    Although tropical forests play an active role in the global carbon cycle and climate, their growth history remains poorly characterized compared to other ecosystems on the planet. Trees are prime candidates for the extraction of paleoclimate archives as they can be probed sub-annually, are widely distributed and can live for over 1400 years. However, dendrochronological techniques have found limited applications in the tropics because trees often lack visible growth rings. Alternative methods exist (dendrometry, radio- and stable isotopes), but the derived records are either of short-duration, lack seasonal resolution or are prohibitively labor intensive to produce. Here, we show the first X-ray microprobe synchrotron record of calcium (Ca) from a ringless Miliusa velutina tree from Thailand and use it to estimate the tree's age and growth history. The Ca age model agrees within (le)2 years of bomb-radiocarbon age estimates and confirms that the cycles are seasonal. The amplitude of the Ca annual cycle is correlated significantly with growth and annual Ca maxima correlate with the amount of dry season rainfall. Synchrotron measurements are fast and producing sufficient numbers of replicated multi-century tropical dendrochemical climate records now seems analytically feasible

  16. The Application of Absolute Ethanol in the Treatment of Mucocele of the Glands of Blandin-Nuhn.

    Science.gov (United States)

    Zhang, Jun; Wang, Chao

    2016-10-01

    Mucocele of the anterior lingual salivary glands is a more common cystic lesion, especially in patients aged less than 20 years. The study is aimed to observe the effect of treatment by injection of absolute ethanol instead of surgery. Fourteen outpatients diagnosed as mucocele of the glands of Blandin-Nuhn were selected. These patients, after blood investigation, were treated by injection of absolute ethanol into a mucous cavity of lesion under superficial anesthesia with 2% lidocaine once a week and followed up from 3 months to 2 years. Mucocele of the glands of Blandin-Nuhn was extirpated in all patients after 1 to 3 injections. There were no other complications except slight distending pain occurred on the same day when the patients were treated. The recurrence was not observed during the follow-up period. In conclusion, the study suggests that injection of absolute ethanol may be an alternative means for treating mucocele of the glands of Blandin-Nuhn, because it is mininvasive, safe, effective, economic, and simply manipulated compared with surgical treatment.

  17. Absolute Radiometric Calibration of the GÖKTÜRK-2 Satellite Sensor Using Tuz GÖLÜ (landnet Site) from Ndvi Perspective

    Science.gov (United States)

    Sakarya, Ufuk; Hakkı Demirhan, İsmail; Seda Deveci, Hüsne; Teke, Mustafa; Demirkesen, Can; Küpçü, Ramazan; Feray Öztoprak, A.; Efendioğlu, Mehmet; Fehmi Şimşek, F.; Berke, Erdinç; Zübeyde Gürbüz, Sevgi

    2016-06-01

    TÜBİTAK UZAY has conducted a research study on the use of space-based satellite resources for several aspects of agriculture. Especially, there are two precision agriculture related projects: HASSAS (Widespread application of sustainable precision agriculture practices in Southeastern Anatolia Project Region (GAP) Project) and AKTAR (Smart Agriculture Feasibility Project). The HASSAS project aims to study development of precision agriculture practice in GAP region. Multi-spectral satellite imagery and aerial hyperspectral data along with ground measurements was collected to analyze data in an information system. AKTAR aims to develop models for irrigation, fertilization and spectral signatures of crops in Inner Anatolia. By the end of the project precision agriculture practices to control irrigation, fertilization, pesticide and estimation of crop yield will be developed. Analyzing the phenology of crops using NDVI is critical for the projects. For this reason, absolute radiometric calibration of the Red and NIR bands in space-based satellite sensors is an important issue. The Göktürk-2 satellite is an earth observation satellite which was designed and built in Turkey and was launched in 2012. The Göktürk-2 satellite sensor has a resolution 2.5 meters in panchromatic and 5 meters in R/G/B/NIR bands. The absolute radiometric calibration of the Göktürk-2 satellite sensor was performed via the ground-based measurements - spectra-radiometer, sun photometer, and meteorological station- in Tuz Gölü cal/val site in 2015. In this paper, the first ground-based absolute radiometric calibration results of the Göktürk-2 satellite sensor using Tuz Gölü is demonstrated. The absolute radiometric calibration results of this paper are compared with the published cross-calibration results of the Göktürk-2 satellite sensor utilizing Landsat 8 imagery. According to the experimental comparison results, the Göktürk-2 satellite sensor coefficients for red and NIR bands

  18. ABSOLUTE RADIOMETRIC CALIBRATION OF THE GÖKTÜRK-2 SATELLITE SENSOR USING TUZ GÖLÜ (LANDNET SITE FROM NDVI PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    U. Sakarya

    2016-06-01

    Full Text Available TÜBİTAK UZAY has conducted a research study on the use of space-based satellite resources for several aspects of agriculture. Especially, there are two precision agriculture related projects: HASSAS (Widespread application of sustainable precision agriculture practices in Southeastern Anatolia Project Region (GAP Project and AKTAR (Smart Agriculture Feasibility Project. The HASSAS project aims to study development of precision agriculture practice in GAP region. Multi-spectral satellite imagery and aerial hyperspectral data along with ground measurements was collected to analyze data in an information system. AKTAR aims to develop models for irrigation, fertilization and spectral signatures of crops in Inner Anatolia. By the end of the project precision agriculture practices to control irrigation, fertilization, pesticide and estimation of crop yield will be developed. Analyzing the phenology of crops using NDVI is critical for the projects. For this reason, absolute radiometric calibration of the Red and NIR bands in space-based satellite sensors is an important issue. The Göktürk-2 satellite is an earth observation satellite which was designed and built in Turkey and was launched in 2012. The Göktürk-2 satellite sensor has a resolution 2.5 meters in panchromatic and 5 meters in R/G/B/NIR bands. The absolute radiometric calibration of the Göktürk-2 satellite sensor was performed via the ground-based measurements - spectra-radiometer, sun photometer, and meteorological station- in Tuz Gölü cal/val site in 2015. In this paper, the first ground-based absolute radiometric calibration results of the Göktürk-2 satellite sensor using Tuz Gölü is demonstrated. The absolute radiometric calibration results of this paper are compared with the published cross-calibration results of the Göktürk-2 satellite sensor utilizing Landsat 8 imagery. According to the experimental comparison results, the Göktürk-2 satellite sensor coefficients for

  19. Redetermination and absolute configuration of atalaphylline

    Directory of Open Access Journals (Sweden)

    Hoong-Kun Fun

    2010-02-01

    Full Text Available The title acridone alkaloid [systematic name: 1,3,5-trihydroxy-2,4-bis(3-methylbut-2-enylacridin-9(10H-one], C23H25NO4, has previously been reported as crystallizing in the chiral orthorhombic space group P212121 [Chantrapromma et al. (2010. Acta Cryst. E66, o81–o82] but the absolute configuration could not be determined from data collected with Mo radiation. The absolute configuration has now been determined by refinement of the Flack parameter with data collected using Cu radiation. All features of the molecule and its crystal packing are similar to those previously described.

  20. Absolute calibration of sniffer probes on Wendelstein 7-X

    International Nuclear Information System (INIS)

    Moseev, D.; Laqua, H. P.; Marsen, S.; Stange, T.; Braune, H.; Erckmann, V.; Gellert, F.; Oosterbeek, J. W.

    2016-01-01

    Here we report the first measurements of the power levels of stray radiation in the vacuum vessel of Wendelstein 7-X using absolutely calibrated sniffer probes. The absolute calibration is achieved by using calibrated sources of stray radiation and the implicit measurement of the quality factor of the Wendelstein 7-X empty vacuum vessel. Normalized absolute calibration coefficients agree with the cross-calibration coefficients that are obtained by the direct measurements, indicating that the measured absolute calibration coefficients and stray radiation levels in the vessel are valid. Close to the launcher, the stray radiation in the empty vessel reaches power levels up to 340 kW/m 2 per MW injected beam power. Furthest away from the launcher, i.e., half a toroidal turn, still 90 kW/m 2 per MW injected beam power is measured.

  1. Absolute calibration of sniffer probes on Wendelstein 7-X

    Science.gov (United States)

    Moseev, D.; Laqua, H. P.; Marsen, S.; Stange, T.; Braune, H.; Erckmann, V.; Gellert, F.; Oosterbeek, J. W.

    2016-08-01

    Here we report the first measurements of the power levels of stray radiation in the vacuum vessel of Wendelstein 7-X using absolutely calibrated sniffer probes. The absolute calibration is achieved by using calibrated sources of stray radiation and the implicit measurement of the quality factor of the Wendelstein 7-X empty vacuum vessel. Normalized absolute calibration coefficients agree with the cross-calibration coefficients that are obtained by the direct measurements, indicating that the measured absolute calibration coefficients and stray radiation levels in the vessel are valid. Close to the launcher, the stray radiation in the empty vessel reaches power levels up to 340 kW/m2 per MW injected beam power. Furthest away from the launcher, i.e., half a toroidal turn, still 90 kW/m2 per MW injected beam power is measured.

  2. Absolute calibration of sniffer probes on Wendelstein 7-X

    Energy Technology Data Exchange (ETDEWEB)

    Moseev, D., E-mail: dmitry.moseev@ipp.mpg.de; Laqua, H. P.; Marsen, S.; Stange, T.; Braune, H.; Erckmann, V. [Max-Planck-Institut für Plasmaphysik, Greifswald (Germany); Gellert, F. [Max-Planck-Institut für Plasmaphysik, Greifswald (Germany); Ernst-Moritz-Arndt-Universität Greifswald, Greifswald (Germany); Oosterbeek, J. W. [Eindhoven University of Technology, Eindhoven (Netherlands)

    2016-08-15

    Here we report the first measurements of the power levels of stray radiation in the vacuum vessel of Wendelstein 7-X using absolutely calibrated sniffer probes. The absolute calibration is achieved by using calibrated sources of stray radiation and the implicit measurement of the quality factor of the Wendelstein 7-X empty vacuum vessel. Normalized absolute calibration coefficients agree with the cross-calibration coefficients that are obtained by the direct measurements, indicating that the measured absolute calibration coefficients and stray radiation levels in the vessel are valid. Close to the launcher, the stray radiation in the empty vessel reaches power levels up to 340 kW/m{sup 2} per MW injected beam power. Furthest away from the launcher, i.e., half a toroidal turn, still 90 kW/m{sup 2} per MW injected beam power is measured.

  3. Pharmacokinetics and absolute bioavailability of phenobarbital in neonates and young infants, a population pharmacokinetic modelling approach.

    Science.gov (United States)

    Marsot, Amélie; Brevaut-Malaty, Véronique; Vialet, Renaud; Boulamery, Audrey; Bruguerolle, Bernard; Simon, Nicolas

    2014-08-01

    Phenobarbital is widely used for treatment of neonatal seizures. Its optimal use in neonates and young infants requires information regarding pharmacokinetics. The objective of this study is to characterize the absolute bioavailability of phenobarbital in neonates and young infants, a pharmacokinetic parameter which has not yet been investigated. Routine clinical pharmacokinetic data were retrospectively collected from 48 neonates and infants (weight: 0.7-10 kg; patient's postnatal age: 0-206 days; GA: 27-42 weeks) treated with phenobarbital, who were administered as intravenous or suspension by oral routes and hospitalized in a paediatric intensive care unit. Total mean dose of 4.6 mg/kg (3.1-10.6 mg/kg) per day was administered by 30-min infusion or by oral route. Pharmacokinetic analysis was performed using a nonlinear mixed-effect population model software). Data were modelled with an allometric pharmacokinetic model, using three-fourths scaling exponent for clearance (CL). The population typical mean [per cent relative standard error (%RSE)] values for CL, apparent volume of distribution (Vd ) and bioavailability (F) were 0.0054 L/H/kg (7%), 0.64 L/kg (15%) and 48.9% (22%), respectively. The interindividual variability of CL, Vd , F (%RSE) and residual variability (%RSE) was 17% (31%), 50% (27%), 39% (27%) and 7.2 mg/L (29%), respectively. The absolute bioavailability of phenobarbital in neonates and infants was estimated. The dose should be increased when switching from intravenous to oral administration. © 2013 Société Française de Pharmacologie et de Thérapeutique. Published by John Wiley & Sons Ltd.

  4. Estimated incidence of pertussis in people aged <50 years in the United States

    Science.gov (United States)

    Chen, Chi-Chang; Balderston McGuiness, Catherine; Krishnarajah, Girishanthy; Blanchette, Christopher M.; Wang, Yuanyuan; Sun, Kainan; Buck, Philip O.

    2016-01-01

    ABSTRACT The introduction of pertussis vaccination in the United States (US) in the 1940s has greatly reduced its burden. However, the incidence of pertussis is difficult to quantify, as many cases are not laboratory-confirmed or reported, particularly in adults. This study estimated pertussis incidence in a commercially insured US population aged pertussis or cough illness using International Classification of Diseases (ICD-9) codes, a commercial outpatient laboratory database for patients with a pertussis laboratory test, and the Centers for Disease Control influenza surveillance database. US national pertussis incidence was projected using 3 methods: (1) diagnosed pertussis, defined as a claim for pertussis (ICD-9 033.0, 033.9, 484.3) during 2008–2013; (2) based on proxy pertussis predictive logistic regression models; (3) using the fraction of cough illness (ICD-9 033.0, 033.9, 484.3, 786.2, 466.0, 466.1, 487.1) attributed to laboratory-confirmed pertussis, estimated by time series linear regression models. Method 1 gave a projected annual incidence of diagnosed pertussis of 9/100,000, which was highest in those aged pertussis of 649/100,000, approximately 58–93 times higher than method 1 depending on the year. These estimations, which are consistent with considerable underreporting of pertussis in people aged pertussis burden. PMID:27246119

  5. Apophyseal Ossification of the Iliac Crest in Forensic Age Estimation: Computed Tomography Standards for Modern Australian Subadults.

    Science.gov (United States)

    Lottering, Nicolene; Alston-Knox, Clair L; MacGregor, Donna M; Izatt, Maree T; Grant, Caroline A; Adam, Clayton J; Gregory, Laura S

    2017-03-01

    This study contrasts the ontogeny of the iliac crest apophysis using conventional radiography and multislice computed tomography (MSCT), providing probabilistic information for age estimation of modern Australian subadults. Retrospective abdominopelvic MSCT data acquired from 524 Australian individuals aged 7-25 and surveillance radiographs of adolescent idiopathic scoliosis patients included in the Paediatric Spine Research Group Progression Study (n = 531) were assessed. Ossification scoring of pseudo-radiographs and three-dimensional (3D) volume-rendered reconstructions using Risser (1958) quantitative descriptors indicate discrepancies in age estimates, stage allocation, and conflicting morphological progression. To mitigate visualization limitations associated with two-dimensional radiographs, we provide and validate a modified 3D-MSCT scoring tier of ossification, demonstrating complete fusion between 17.3-19.2 and 17.1-20.1 years in males and females. Legal demarcation for doli incapax presumption and age of majority (18 years) can be achieved using probability estimates from a fitted cumulative probit model for apophyseal fusion using the recalibrated standards. © 2016 American Academy of Forensic Sciences.

  6. Absolute magnitudes by statistical parallaxes

    International Nuclear Information System (INIS)

    Heck, A.

    1978-01-01

    The author describes an algorithm for stellar luminosity calibrations (based on the principle of maximum likelihood) which allows the calibration of relations of the type: Msub(i)=sup(N)sub(j=1)Σqsub(j)Csub(ij), i=1,...,n, where n is the size of the sample at hand, Msub(i) are the individual absolute magnitudes, Csub(ij) are observational quantities (j=1,...,N), and qsub(j) are the coefficients to be determined. If one puts N=1 and Csub(iN)=1, one has q 1 =M(mean), the mean absolute magnitude of the sample. As additional output, the algorithm provides one also with the dispersion in magnitude of the sample sigmasub(M), the mean solar motion (U,V,W) and the corresponding velocity ellipsoid (sigmasub(u), sigmasub(v), sigmasub(w). The use of this algorithm is illustrated. (Auth.)

  7. Strongly nonlinear theory of rapid solidification near absolute stability

    Science.gov (United States)

    Kowal, Katarzyna N.; Altieri, Anthony L.; Davis, Stephen H.

    2017-10-01

    We investigate the nonlinear evolution of the morphological deformation of a solid-liquid interface of a binary melt under rapid solidification conditions near two absolute stability limits. The first of these involves the complete stabilization of the system to cellular instabilities as a result of large enough surface energy. We derive nonlinear evolution equations in several limits in this scenario and investigate the effect of interfacial disequilibrium on the nonlinear deformations that arise. In contrast to the morphological stability problem in equilibrium, in which only cellular instabilities appear and only one absolute stability boundary exists, in disequilibrium the system is prone to oscillatory instabilities and a second absolute stability boundary involving attachment kinetics arises. Large enough attachment kinetics stabilize the oscillatory instabilities. We derive a nonlinear evolution equation to describe the nonlinear development of the solid-liquid interface near this oscillatory absolute stability limit. We find that strong asymmetries develop with time. For uniform oscillations, the evolution equation for the interface reduces to the simple form f''+(βf')2+f =0 , where β is the disequilibrium parameter. Lastly, we investigate a distinguished limit near both absolute stability limits in which the system is prone to both cellular and oscillatory instabilities and derive a nonlinear evolution equation that captures the nonlinear deformations in this limit. Common to all these scenarios is the emergence of larger asymmetries in the resulting shapes of the solid-liquid interface with greater departures from equilibrium and larger morphological numbers. The disturbances additionally sharpen near the oscillatory absolute stability boundary, where the interface becomes deep-rooted. The oscillations are time-periodic only for small-enough initial amplitudes and their frequency depends on a single combination of physical parameters, including the

  8. Enantiomeric Mixtures in Natural Product Chemistry: Separation and Absolute Configuration Assignment.

    Science.gov (United States)

    N L Batista, Andrea; M Dos Santos, Fernando; Batista, João M; Cass, Quezia B

    2018-02-23

    Chiral natural product molecules are generally assumed to be biosynthesized in an enantiomerically pure or enriched fashion. Nevertheless, a significant amount of racemates or enantiomerically enriched mixtures has been reported from natural sources. This number is estimated to be even larger since the enantiomeric purity of secondary metabolites is rarely checked in the natural product isolation pipeline. This latter fact may have drastic effects on the evaluation of the biological activity of chiral natural products. A second bottleneck is the determination of their absolute configurations. Despite the widespread use of optical rotation and electronic circular dichroism, most of the stereochemical assignments are based on empirical correlations with similar compounds reported in the literature. As an alternative, the combination of vibrational circular dichroism and quantum chemical calculations has emerged as a powerful and reliable tool for both conformational and configurational analysis of natural products, even for those lacking UV-Vis chromophores. In this review, we aim to provide the reader with a critical overview of the occurrence of enantiomeric mixtures of secondary metabolites in nature as well the best practices for their detection, enantioselective separation using liquid chromatography, and determination of absolute configuration by means of vibrational circular dichroism and density functional theory calculations.

  9. Magnetic resonance imaging of third molars: developing a protocol suitable for forensic age estimation.

    Science.gov (United States)

    De Tobel, Jannick; Hillewig, Elke; Bogaert, Stephanie; Deblaere, Karel; Verstraete, Koenraad

    2017-03-01

    Established dental age estimation methods in sub-adults study the development of third molar root apices on radiographs. In living individuals, however, avoiding ionising radiation is expedient. Studying dental development with magnetic resonance imaging complies with this requirement, adding the advantage of imaging in three dimensions. To elaborate the development of an MRI protocol to visualise all third molars for forensic age estimation, with particular attention to the development of the root apex. Ex vivo scans of porcine jaws and in vivo scans of 10 volunteers aged 17-25 years were performed to select adequate sequences. Studied parameters were T1 vs T2 weighting, ultrashort echo time (UTE), fat suppression, in plane resolution, slice thickness, 3D imaging, signal-to-noise ratio, and acquisition time. A bilateral four-channel flexible surface coil was used. Two observers evaluated the suitability of the images. T2-weighted images were preferred to T1-weighted images. To clearly distinguish root apices in (almost) fully developed third molars an in plane resolution of 0.33 × 0.33 mm 2 was deemed necessary. Taking acquisition time limits into account, only a T2 FSE sequence with slice thickness of 2 mm generated images with sufficient resolution and contrast. UTE, thinner slice T2 FSE and T2 3D FSE sequences could not generate the desired resolution within 6.5 minutes. Three Tesla MRI of the third molars is a feasible technique for forensic age estimation, in which a T2 FSE sequence can provide the desired in plane resolution within a clinically acceptable acquisition time.

  10. The use of absolute gravity data for the validation of Global Geopotential Models and for improving quasigeoid heights determined from satellite-only Global Geopotential Models

    Science.gov (United States)

    Godah, Walyeldeen; Krynski, Jan; Szelachowska, Malgorzata

    2018-05-01

    The objective of this paper is to demonstrate the usefulness of absolute gravity data for the validation of Global Geopotential Models (GGMs). It is also aimed at improving quasigeoid heights determined from satellite-only GGMs using absolute gravity data. The area of Poland, as a unique one, covered with a homogeneously distributed set of absolute gravity data, has been selected as a study area. The gravity anomalies obtained from GGMs were validated using the corresponding ones determined from absolute gravity data. The spectral enhancement method was implemented to overcome the spectral inconsistency in data being validated. The quasigeoid heights obtained from the satellite-only GGM as well as from the satellite-only GGM in combination with absolute gravity data were evaluated with high accuracy GNSS/levelling data. Estimated accuracy of gravity anomalies obtained from GGMs investigated is of 1.7 mGal. Considering omitted gravity signal, e.g. from degree and order 101 to 2190, satellite-only GGMs can be validated at the accuracy level of 1 mGal using absolute gravity data. An improvement up to 59% in the accuracy of quasigeoid heights obtained from the satellite-only GGM can be observed when combining the satellite-only GGM with absolute gravity data.

  11. Forcing absoluteness and regularity properties

    NARCIS (Netherlands)

    Ikegami, D.

    2010-01-01

    For a large natural class of forcing notions, we prove general equivalence theorems between forcing absoluteness statements, regularity properties, and transcendence properties over L and the core model K. We use our results to answer open questions from set theory of the reals.

  12. Ten-year absolute risk of osteoporotic fractures according to BMD T score at menopause: the Danish Osteoporosis Prevention Study

    DEFF Research Database (Denmark)

    Abrahamsen, Bo; Vestergaard, Peter; Rud, Bo

    2006-01-01

    was 10.9% as opposed to an expected risk of 5.7%. Relative risk gradients were similar to those of the recent meta-analysis. CONCLUSIONS: In healthy women, examined in the first year or two after menopause, 10-year fracture risk was higher at each level of BMD T score than expected from the model...... by Kanis et al. Inclusion of HRT users in the cohorts used may have led to higher BMD values and lower absolute fracture risk in the Kanis model. These longitudinal data can be used directly in estimating absolute fracture risk in untreated north European women from BMD at menopause....

  13. Using Landsat TM and NFI data to estimate wood volume, tree biomass and stand age in Dalarna

    Energy Technology Data Exchange (ETDEWEB)

    Reese, Heather; Nilsson, Mats

    1999-10-01

    As part of the `Monitoring of forest ecosystems` project, within the MISTRA program Remote Sensing for the Environment (RESE), and also with funding from the County Administration Board of Dalarna, a demonstration project was undertaken to estimate forest stand parameters in Dalarna with the use of satellite data. Using two full scenes of Landsat Thematic Mapper data and sample plot data from the Swedish National Forest Inventory, estimations of above ground tree biomass, age, total wood volume, and separate tree species volumes were made using the `k Nearest Neighbor` method. Accuracy assessment results at the single pixel level for total wood volume are consistent with results from previous kNN estimations, with an overall relative RMSE of 75% for the western scene, and 58% overall relative RMSE for the eastern scene. Validation data show a bias of the estimate toward the mean value of the estimation data. The pixel level estimates of above ground tree biomass and age had similar validation results to those for total wood volume. Biomass estimates had a 77% relative RMSE for the western scene, and 69% for the eastern scene. Age estimates had a relative RMSE of 60% in the western scene and 57% in the eastern scene. The results may suggest the need to incorporate a geographic limitation on the plots used in the estimation, and to further investigate the co-registration between the satellite and plot data. While pixel lever errors are high, an aggregation of the estimates to larger (compartment-sized) areas could decrease the error significantly. Previous similar studies have shown that an RMSE of 10% for total wood volume can be obtained for as small areas as 100 to 450 hectares. The estimates from this study will be evaluated for use by the County Administration Board of Dalarna to find areas of ecological interest and to assist in planning 14 refs, 4 figs, 4 tabs

  14. A New Form of Nondestructive Strength-Estimating Statistical Models Accounting for Uncertainty of Model and Aging Effect of Concrete

    International Nuclear Information System (INIS)

    Hong, Kee Jeung; Kim, Jee Sang

    2009-01-01

    As concrete ages, the surrounding environment is expected to have growing influences on the concrete. As all the impacts of the environment cannot be considered in the strength-estimating model of a nondestructive concrete test, the increase in concrete age leads to growing uncertainty in the strength-estimating model. Therefore, the variation of the model error increases. It is necessary to include those impacts in the probability model of concrete strength attained from the nondestructive tests so as to build a more accurate reliability model for structural performance evaluation. This paper reviews and categorizes the existing strength-estimating statistical models of nondestructive concrete test, and suggests a new form of the strength-estimating statistical models to properly reflect the model uncertainty due to aging of the concrete. This new form of the statistical models will lay foundation for more accurate structural performance evaluation.

  15. Absolute calibration of sniffer probes on Wendelstein 7-X

    NARCIS (Netherlands)

    Moseev, D.; Laqua, H.P.; Marsen, S.; Stange, T.; Braune, H.; Erckmann, V.; Gellert, F.J.; Oosterbeek, J.W.

    Here we report the first measurements of the power levels of stray radiation in the vacuum vessel of Wendelstein 7-X using absolutely calibrated sniffer probes. The absolute calibration is achieved by using calibrated sources of stray radiation and the implicit measurement of the quality factor of

  16. Absolute tense forms in Tswana | Pretorius | Journal for Language ...

    African Journals Online (AJOL)

    These views were compared in an attempt to put forth an applicable framework for the classification of the tenses in Tswana and to identify the absolute tenses of Tswana. Keywords: tense; simple tenses; compound tenses; absolute tenses; relative tenses; aspect; auxiliary verbs; auxiliary verbal groups; Tswana Opsomming

  17. Learning-based encoding with soft assignment for age estimation under unconstrained imaging conditions

    NARCIS (Netherlands)

    Alnajar, F.; Shan, C.; Gevers, T.; Geusebroek, J.M.

    2012-01-01

    In this paper we propose to adopt a learning-based encoding method for age estimation under unconstrained imaging conditions. A similar approach [Cao et al., 2010] is applied to face recognition in real-life face images. However, the feature vectors are encoded in hard manner i.e. each feature

  18. GEM: Performance and aging tests

    International Nuclear Information System (INIS)

    Cho, H.S.; Kadyk, J.; Han, S.H.; Hong, W.S.; Perez-Mendez, V.; Wenzel, W.; Pitts, K.; Martin, M.D.; Hutchins, J.B.

    1999-01-01

    Performance and aging tests have been done to characterize Gas Electron Multipliers (GEMs), including further design improvements such as a thicker GEM and a closed GEM. Since the effective GEM gain is typically smaller than the absolute GEM gain, due to trapping of avalanche electrons at the bottom GEM electrode, the authors performed field simulations and measurements for better understanding, and discuss methods to eliminate this effect. Other performance parameters of the GEMs are also presented, including absolute GEM gain, short-term and long-term gain stabilities

  19. Probative value of absolute and relative judgments in eyewitness identification.

    Science.gov (United States)

    Clark, Steven E; Erickson, Michael A; Breneman, Jesse

    2011-10-01

    It is well-accepted that eyewitness identification decisions based on relative judgments are less accurate than identification decisions based on absolute judgments. However, the theoretical foundation for this view has not been established. In this study relative and absolute judgments were compared through simulations of the WITNESS model (Clark, Appl Cogn Psychol 17:629-654, 2003) to address the question: Do suspect identifications based on absolute judgments have higher probative value than suspect identifications based on relative judgments? Simulations of the WITNESS model showed a consistent advantage for absolute judgments over relative judgments for suspect-matched lineups. However, simulations of same-foils lineups showed a complex interaction based on the accuracy of memory and the similarity relationships among lineup members.

  20. Absolute standardization of radionuclides with complex decay by the peak-sum coincidence method and photon spectrometry with HPGe detector

    International Nuclear Information System (INIS)

    Silva, Ronaldo Lins da

    2017-01-01

    This study aims to present a new methodology for absolute standardization of 133 Ba, which is a complex decay radionuclide, using the peak-sum coincidence method associated with gamma spectrometry with a high resolution germanium detector. The use of the method of direct multiplication of matrices allowed identifying all the energies of sum coincidence, as well as their probabilities of detection, which made possible the calculation of the probabilities of detecting the energies of interferences. In addition, with the use of deconvolution software it was possible to obtain the areas of energy without interference of other sums, and by means of the deduced equation for the peak sum method, it was possible to standardize 133 Ba. The result of the activity was compared with those found by the absolute methods existing in the LNMRI, where the result obtained by coincidence peak-sum was highlighted among all. The estimated uncertainties were below 0.30%, compatible with the results found in the literature by other absolute methods. Thus, it was verified that the methodology was able to standardize radionuclide 133 Ba with precision, accuracy, easiness and quickness. The relevance of this doctoral thesis is to provide the National Metrology Laboratory of Ionizing Radiation (LNMRI) with a new absolute standardization methodology for complex decay radionuclides. (author)

  1. Age- and sex-dependent model for estimating radioiodine dose to a normal thyroid

    International Nuclear Information System (INIS)

    Killough, G.G.; Eckerman, K.F.

    1985-01-01

    This paper describes the derivation of an age- and sex-dependent model of radioiodine dosimetry in the thyroid and the application of the model to estimating the thyroid dose for each of 4215 patients who were exposed to 131 I in diagnostic and therapeutic procedures. The model was made to conform to these data requirements by the use of age-specific estimates of the biological half-time of iodine in the thyroid and an age- and sex-dependent representation of the mass of the thyroid. Also, it was assumed that the thyroid burden was maximum 24 hours after administration (the 131 I dose is not critically sensitive to this assumption). The metabolic model is of the form A(t) = K[exp(-μ 1 t) - exp(-μ 2 t)] (μCi), where μ 1 = lambda/sub r/ + lambda/sub i//sup b/ (i = 1, 2), lambda/sub r/ is the radiological decay-rate coefficient, and lambda/sub i//sup b/ are biological removal rate coefficients. The values of lambda/sub i//sup b/ are determined by solving a nonlinear equation that depends on assumptions about the time of maximum uptake and the eventual biological loss rate (through which age dependence enters). The value of K may then be calculated from knowledge of the uptake at a particular time. The dosimetric S-factor (rad/μCi-day) is based on specific absorbed fractions for photons of energy ranging from 0.01 to 4.0 MeV for thyroid masses from 1.29 to 19.6 g; the functional form of the S-factor also involves the thyroid mass explicitly, through which the dependence on age and sex enters. An analysis of sensitivity of the model to uncertainties in the thyroid mass and the biological removal rate for several age groups is reported. The model could prove useful in the dosimetry of very short-lived radioiodines. Tables of age- and sex-dependent coefficients are provided to enable readers to make their own calculations. 12 refs., 5 figs., 4 tabs

  2. Positioning, alignment and absolute pointing of the ANTARES neutrino telescope

    International Nuclear Information System (INIS)

    Fehr, F; Distefano, C

    2010-01-01

    A precise detector alignment and absolute pointing is crucial for point-source searches. The ANTARES neutrino telescope utilises an array of hydrophones, tiltmeters and compasses for the relative positioning of the optical sensors. The absolute calibration is accomplished by long-baseline low-frequency triangulation of the acoustic reference devices in the deep-sea with a differential GPS system at the sea surface. The absolute pointing can be independently verified by detecting the shadow of the Moon in cosmic rays.

  3. Does Absolute Synonymy exist in Owere-Igbo? | Omego | AFRREV ...

    African Journals Online (AJOL)

    Among Igbo linguistic researchers, determining whether absolute synonymy exists in Owere–Igbo, a dialect of the Igbo language predominantly spoken by the people of Owerri, Imo State, Nigeria, has become a thorny issue. While some linguistic scholars strive to establish that absolute synonymy exists in the lexical ...

  4. Age- and gender-specific estimates of partnership formation and dissolution rates in the Seattle sex survey.

    Science.gov (United States)

    Nelson, Sara J; Hughes, James P; Foxman, Betsy; Aral, Sevgi O; Holmes, King K; White, Peter J; Golden, Matthew R

    2010-04-01

    Partnership formation and dissolution rates are primary determinants of sexually transmitted infection (STI) transmission dynamics. The authors used data on persons' lifetime sexual experiences from a 2003-2004 random digit dialing survey of Seattle residents aged 18-39 years (N=1,194) to estimate age- and gender-specific partnership formation and dissolution rates. Partnership start and end dates were used to estimate participants' ages at the start of each partnership and partnership durations, and partnerships not enumerated in the survey were imputed. Partnership formation peaked at age 19 at 0.9 (95% confidence interval [CI]: 0.76-1.04) partnerships per year and decreased to 0.1 to 0.2 after age 30 for women and peaked at age 20 at 1.4 (95% CI: 1.08-1.64) and declined to 0.5 after age 30 for men. Nearly one fourth (23.7%) of partnerships ended within 1 week and more than one half (51.2%) ended within 12 weeks. Most (63.5%) individuals 30 to 39 years of age had not formed a new sexual partnership in the past 3 years. A large proportion of the heterosexual population is no longer at substantial STI risk by their early 30s, but similar analyses among high-risk populations may give insight into reasons for the profound disparities in STI rates across populations. Copyright (c) 2010 Elsevier Inc. All rights reserved.

  5. Estimating absolute sea level variations by combining GNSS and Tide gauge data

    Digital Repository Service at National Institute of Oceanography (India)

    Bos, M.S.; Fernandes, R.M.S; Vethamony, P.; Mehra, P.

    Indian tide gauges can be used to estimate sea level rise. To separate relative sea level rise from vertical land motion at the tide gauges, various GNSS stations have been installed in the last years at, or nearby, tide gauges. Using the PSMSL...

  6. Forensic age estimation from the clavicle using 1.0 T MRI—Preliminary results

    DEFF Research Database (Denmark)

    Larsen, Sara Tangmose; Jensen, Karl Erik; Villa, Chiara

    2014-01-01

    OBJECTIVES: As forensic age estimations in the living are performed without medical indication, there is a need for the development of non-ionizing methods. This study investigates the use of 1.0T MRI to visualize the ossification status of the medial end of the clavicle. MATERIAL AND METHODS: T2...

  7. Nonparametric estimation of age-specific reference percentile curves with radial smoothing.

    Science.gov (United States)

    Wan, Xiaohai; Qu, Yongming; Huang, Yao; Zhang, Xiao; Song, Hanping; Jiang, Honghua

    2012-01-01

    Reference percentile curves represent the covariate-dependent distribution of a quantitative measurement and are often used to summarize and monitor dynamic processes such as human growth. We propose a new nonparametric method based on a radial smoothing (RS) technique to estimate age-specific reference percentile curves assuming the underlying distribution is relatively close to normal. We compared the RS method with both the LMS and the generalized additive models for location, scale and shape (GAMLSS) methods using simulated data and found that our method has smaller estimation error than the two existing methods. We also applied the new method to analyze height growth data from children being followed in a clinical observational study of growth hormone treatment, and compared the growth curves between those with growth disorders and the general population. Copyright © 2011 Elsevier Inc. All rights reserved.

  8. Age estimation by assessment of pulp chamber volume: a Bayesian network for the evaluation of dental evidence.

    Science.gov (United States)

    Sironi, Emanuele; Taroni, Franco; Baldinotti, Claudio; Nardi, Cosimo; Norelli, Gian-Aristide; Gallidabino, Matteo; Pinchi, Vilma

    2017-11-14

    The present study aimed to investigate the performance of a Bayesian method in the evaluation of dental age-related evidence collected by means of a geometrical approximation procedure of the pulp chamber volume. Measurement of this volume was based on three-dimensional cone beam computed tomography images. The Bayesian method was applied by means of a probabilistic graphical model, namely a Bayesian network. Performance of that method was investigated in terms of accuracy and bias of the decisional outcomes. Influence of an informed elicitation of the prior belief of chronological age was also studied by means of a sensitivity analysis. Outcomes in terms of accuracy were adequate with standard requirements for forensic adult age estimation. Findings also indicated that the Bayesian method does not show a particular tendency towards under- or overestimation of the age variable. Outcomes of the sensitivity analysis showed that results on estimation are improved with a ration elicitation of the prior probabilities of age.

  9. Errors in 'BED'-derived estimates of HIV incidence will vary by place, time and age.

    Directory of Open Access Journals (Sweden)

    Timothy B Hallett

    2009-05-01

    Full Text Available The BED Capture Enzyme Immunoassay, believed to distinguish recent HIV infections, is being used to estimate HIV incidence, although an important property of the test--how specificity changes with time since infection--has not been not measured.We construct hypothetical scenarios for the performance of BED test, consistent with current knowledge, and explore how this could influence errors in BED estimates of incidence using a mathematical model of six African countries. The model is also used to determine the conditions and the sample sizes required for the BED test to reliably detect trends in HIV incidence.If the chance of misclassification by BED increases with time since infection, the overall proportion of individuals misclassified could vary widely between countries, over time, and across age-groups, in a manner determined by the historic course of the epidemic and the age-pattern of incidence. Under some circumstances, changes in BED estimates over time can approximately track actual changes in incidence, but large sample sizes (50,000+ will be required for recorded changes to be statistically significant.The relationship between BED test specificity and time since infection has not been fully measured, but, if it decreases, errors in estimates of incidence could vary by place, time and age-group. This means that post-assay adjustment procedures using parameters from different populations or at different times may not be valid. Further research is urgently needed into the properties of the BED test, and the rate of misclassification in a wide range of populations.

  10. Inter-lab comparison of precision and recommended methods for age estimation of Florida manatee (Trichechus manatus latirostris using growth layer groups in earbones

    Directory of Open Access Journals (Sweden)

    Katherine Brill

    2016-06-01

    Full Text Available Manatees are routinely aged by counting Growth Layer Groups (GLGs in periotic bones (earbones. Manatee carcasses recovered in Florida between 1974 and 2010 provided age-estimation material for three readers and formed the base for a retrospective analysis of aging precision (repeatability. All readers were in good agreement (high precision with the greatest apparent source of variation being the result of earbone remodelling with increasing manatee age. Over the same period, methods of sample preparation and of determining a final age estimate changed. We examined the effects of altering methods on ease of reading GLGs and found no statistical differences. Accurate age estimates are an important component for effective management of the species and for better models of population trends and we summarize the currently recommended methods for estimating manatee ages using earbones.

  11. Mortality forecast from gastroduodenal ulcer disease for different gender and age population groups in Ukraine

    Directory of Open Access Journals (Sweden)

    Duzhiy I.D.

    2016-03-01

    Full Text Available Until 2030 the ulcer mortality will have a growing trend as estimated by the World Health Organization. Detection of countries and population groups with high risks for the ulcer mortality is possible using forecast method. The authors made a forecast of mortality rate from complicated ulcer disease in males and females and their age groups (15-24, 25-34, 35-54, 55-74, over 75, 15 - over 75 in our country. The study included data of the World Health Organization Database from 1991 to 2012. The work analyzed absolute all-Ukrainian numbers of persons of both genders died from the ulcer causes (К25-К27 coded by the 10th International Diseases Classification. The relative mortality per 100 000 of alive persons of the same age was calculated de novo. The analysis of distribution laws and their estimation presents a trend of growth of the relative mortality. A remarkable increase of deaths from the ulcer disease is observed in males and females of the age after 55 years old. After the age of 75 years this trend is more expressed.

  12. BFEE: A User-Friendly Graphical Interface Facilitating Absolute Binding Free-Energy Calculations.

    Science.gov (United States)

    Fu, Haohao; Gumbart, James C; Chen, Haochuan; Shao, Xueguang; Cai, Wensheng; Chipot, Christophe

    2018-03-26

    Quantifying protein-ligand binding has attracted the attention of both theorists and experimentalists for decades. Many methods for estimating binding free energies in silico have been reported in recent years. Proper use of the proposed strategies requires, however, adequate knowledge of the protein-ligand complex, the mathematical background for deriving the underlying theory, and time for setting up the simulations, bookkeeping, and postprocessing. Here, to minimize human intervention, we propose a toolkit aimed at facilitating the accurate estimation of standard binding free energies using a geometrical route, coined the binding free-energy estimator (BFEE), and introduced it as a plug-in of the popular visualization program VMD. Benefitting from recent developments in new collective variables, BFEE can be used to generate the simulation input files, based solely on the structure of the complex. Once the simulations are completed, BFEE can also be utilized to perform the post-treatment of the free-energy calculations, allowing the absolute binding free energy to be estimated directly from the one-dimensional potentials of mean force in simulation outputs. The minimal amount of human intervention required during the whole process combined with the ergonomic graphical interface makes BFEE a very effective and practical tool for the end-user.

  13. Standardization of a method to calculate absolute renal uptake of 99m Tc-DMSA in children

    International Nuclear Information System (INIS)

    Ono, Carla Rachel; Sapienza, Marcelo Tatit; Watanabe, Tomoco; Costa, Paulo Luiz Aguirre; Okamoto, Miriam Roseli Yoshie; Garcez, Alexandre Teles; Buchpiguel, Carlos Alberto; Machado, Beatriz Marcondes; Machado, Marcia Melo Campos; Liberato Junior, Waldyr de Paula

    2006-01-01

    Objective:To standardize a method and determine normal values for absolute renal uptake of 99m Tc-DMSA in children with normal creatinine clearance. Materials and methods: Twenty-two children (between 7 months and 10 years of age; mean 4.5 years) without clinical evidence of renal disease were studied using 99m Tc-DMSA scintigraphy. Eighteen had normal renal ultrasonography, micturating urethrocystography, creatinine clearance and visual interpretation of the scintigraphy with 99m Tc-DMSA. Four children were excluded, one with incomplete creatinine clearance and three due to reduction in the creatinine clearance. Absolute renal uptake of 99m Tc-DMSA (DMSA-Abs) was expressed as the fraction of the administered dose retained by each kidney six hours after administration of the radiopharmaceutical. Results: DMSA-Abs was 21.8 +- 3.2% for the right kidney and 23.1 +-3.3% for the left kidney. There was no correlation between renal uptake and the age groups studied, although there was a tendency to an increase in the creatinine clearance with age. Conclusion: Normal values of DMSA-Abs can be used as an additional parameter for the initial diagnostic evaluation and during follow-up of renal diseases, mainly when bilateral impairment of renal function is suspected or in a patient with a single functioning kidney (in which renal differential function is of limited value). (author)

  14. Moral absolutism and ectopic pregnancy.

    Science.gov (United States)

    Kaczor, C

    2001-02-01

    If one accepts a version of absolutism that excludes the intentional killing of any innocent human person from conception to natural death, ectopic pregnancy poses vexing difficulties. Given that the embryonic life almost certainly will die anyway, how can one retain one's moral principle and yet adequately respond to a situation that gravely threatens the life of the mother and her future fertility? The four options of treatment most often discussed in the literature are non-intervention, salpingectomy (removal of tube with embryo), salpingostomy (removal of embryo alone), and use of methotrexate (MXT). In this essay, I review these four options and introduce a fifth (the milking technique). In order to assess these options in terms of the absolutism mentioned, it will also be necessary to discuss various accounts of the intention/foresight distinction. I conclude that salpingectomy, salpingostomy, and the milking technique are compatible with absolutist presuppositions, but not the use of methotrexate.

  15. Estimation of Energy Consumption and Greenhouse Gas Emissions considering Aging and Climate Change in Residential Sector

    Science.gov (United States)

    Lee, M.; Park, C.; Park, J. H.; Jung, T. Y.; Lee, D. K.

    2015-12-01

    The impacts of climate change, particularly that of rising temperatures, are being observed across the globe and are expected to further increase. To counter this phenomenon, numerous nations are focusing on the reduction of greenhouse gas (GHG) emissions. Because energy demand management is considered as a key factor in emissions reduction, it is necessary to estimate energy consumption and GHG emissions in relation to climate change. Further, because South Korea is the world's fastest nation to become aged, demographics have also become instrumental in the accurate estimation of energy demands and emissions. Therefore, the purpose of this study is to estimate energy consumption and GHG emissions in the residential sectors of South Korea with regard to climate change and aging to build more accurate strategies for energy demand management and emissions reduction goals. This study, which was stablished with 2010 and 2050 as the base and target years, respectively, was divided into a two-step process. The first step evaluated the effects of aging and climate change on energy demand, and the second estimated future energy use and GHG emissions through projected scenarios. First, aging characteristics and climate change factors were analyzed by using the logarithmic mean divisia index (LMDI) decomposition analysis and the application of historical data. In the analysis of changes in energy use, the effects of activity, structure, and intensity were considered; the degrees of contribution were derived from each effect in addition to their relations to energy demand. Second, two types of scenarios were stablished based on this analysis. The aging scenarios are business as usual and future characteristics scenarios, and were used in combination with Representative Concentration Pathway (RCP) 2.6 and 8.5. Finally, energy consumption and GHG emissions were estimated by using a combination of scenarios. The results of these scenarios show an increase in energy consumption

  16. Accuracy of prehospital transport time estimation.

    Science.gov (United States)

    Wallace, David J; Kahn, Jeremy M; Angus, Derek C; Martin-Gill, Christian; Callaway, Clifton W; Rea, Thomas D; Chhatwal, Jagpreet; Kurland, Kristen; Seymour, Christopher W

    2014-01-01

    Estimates of prehospital transport times are an important part of emergency care system research and planning; however, the accuracy of these estimates is unknown. The authors examined the accuracy of three estimation methods against observed transport times in a large cohort of prehospital patient transports. This was a validation study using prehospital records in King County, Washington, and southwestern Pennsylvania from 2002 to 2006 and 2005 to 2011, respectively. Transport time estimates were generated using three methods: linear arc distance, Google Maps, and ArcGIS Network Analyst. Estimation error, defined as the absolute difference between observed and estimated transport time, was assessed, as well as the proportion of estimated times that were within specified error thresholds. Based on the primary results, a regression estimate was used that incorporated population density, time of day, and season to assess improved accuracy. Finally, hospital catchment areas were compared using each method with a fixed drive time. The authors analyzed 29,935 prehospital transports to 44 hospitals. The mean (± standard deviation [±SD]) absolute error was 4.8 (±7.3) minutes using linear arc, 3.5 (±5.4) minutes using Google Maps, and 4.4 (±5.7) minutes using ArcGIS. All pairwise comparisons were statistically significant (p Google Maps, and 11.6 [±10.9] minutes for ArcGIS). Estimates were within 5 minutes of observed transport time for 79% of linear arc estimates, 86.6% of Google Maps estimates, and 81.3% of ArcGIS estimates. The regression-based approach did not substantially improve estimation. There were large differences in hospital catchment areas estimated by each method. Route-based transport time estimates demonstrate moderate accuracy. These methods can be valuable for informing a host of decisions related to the system organization and patient access to emergency medical care; however, they should be employed with sensitivity to their limitations.

  17. How old are you? Genet age estimates in a clonal animal.

    Science.gov (United States)

    Devlin-Durante, M K; Miller, M W; Precht, W F; Baums, I B

    2016-11-01

    Foundation species such as redwoods, seagrasses and corals are often long-lived and clonal. Genets may consist of hundreds of members (ramets) and originated hundreds to thousands of years ago. As climate change and other stressors exert selection pressure on species, the demography of populations changes. Yet, because size does not indicate age in clonal organisms, demographic models are missing data necessary to predict the resilience of many foundation species. Here, we correlate somatic mutations with genet age of corals and provide the first, preliminary estimates of genet age in a colonial animal. We observed somatic mutations at five microsatellite loci in rangewide samples of the endangered coral, Acropora palmata (n = 3352). Colonies harboured 342 unique mutations in 147 genets. Genet age ranged from 30 to 838 years assuming a mutation rate of 1.195 -04 per locus per year based on colony growth rates and 236 to 6500 years assuming a mutation rate of 1.542 -05 per locus per year based on sea level changes to habitat availability. Long-lived A. palmata genets imply a large capacity to tolerate past environmental change, and yet recent mass mortality events in A. palmata suggest that capacity is now being frequently exceeded. © 2016 John Wiley & Sons Ltd.

  18. An independent distance estimate to the AGB star R Sculptoris

    Science.gov (United States)

    Maercker, M.; Brunner, M.; Mecina, M.; De Beck, E.

    2018-04-01

    Context. Distance measurements to astronomical objects are essential for understanding their intrinsic properties. For asymptotic giant branch (AGB) stars it is particularly difficult to derive accurate distance estimates. Period-luminosity relationships rely on the correlation of different physical properties of the stars, while the angular sizes and variability of AGB stars make parallax measurements inherently inaccurate. For the carbon AGB star R Sculptoris, the uncertain distance significantly affects the interpretation of observations regarding the evolution of the stellar mass loss during and after the most recent thermal pulse. Aim. We aim to provide a new, independent measurement of the distance to R Sculptoris, reducing the absolute uncertainty of the distance estimate to this source. Methods: R Scl is a semi-regular pulsating star, surrounded by a thin shell of dust and gas created during a thermal pulse ≈2000 years ago. The stellar light is scattered by the dust particles in the shell at a radius of ≈19″. The variation in the stellar light affects the amount of dust-scattered light with the same period and amplitude ratio, but with a phase lag that depends on the absolute size of the shell. We measured this phase lag by observing the star R Scl and the dust-scattered stellar light from the shell at five epochs between June-December 2016. By observing in polarised light, we imaged the shell in the plane of the sky, removing any uncertainty due to geometrical effects. The phase lag gives the absolute size of the shell, and together with the angular size of the shell directly gives the absolute distance to R Sculptoris. Results: We measured a phase lag between the stellar variations and the variation in the shell of 40.0 ± 4.0 days. The angular size of the shell is measured to be 19.″1 ± 0.″7. Combined, this gives an absolute distance to R Sculptoris of 361 ± 44 pc. Conclusions: We independently determined the absolute distance to R Scl with

  19. First derivative versus absolute spectral reflectance of citrus varieties

    Science.gov (United States)

    Blazquez, Carlos H.; Nigg, H. N.; Hedley, Lou E.; Ramos, L. E.; Sorrell, R. W.; Simpson, S. E.

    1996-06-01

    Spectral reflectance measurements from 400 to 800 nm were taken from immature and mature leaves of grapefruit ('McCarty' and 'Rio Red'), 'Minneola' tangelo, 'Satsuma' mandarin, 'Dancy' tangerine, 'Nagami' oval kumquat, and 'Valencia' sweet orange, at the Florida Citrus Arboretum, Division of Plant Industry, Winter Haven, Florida. Immature and mature leaves of 'Minneola' tangelo had greater percent reflectance in the 400 to 800 nm range than the other varieties and leaf ages measured. The slope of the citrus spectral curves in the 800 nm range was not as sharp as conventional spectrometers, but had a much higher reflectance value than those obtained with a DK-2 spectrometer. Statistical analyses of absolute spectral data yielded significant differences between mature and immature leaves and between varieties. First derivative data analyses did not yield significant differences between varieties.

  20. Absolute versus relative measures of plasma fatty acids and health outcomes: example of phospholipid omega-3 and omega-6 fatty acids and all-cause mortality in women.

    Science.gov (United States)

    Miura, Kyoko; Hughes, Maria Celia B; Ungerer, Jacobus P J; Smith, David D; Green, Adèle C

    2018-03-01

    In a well-characterised community-based prospective study, we aimed to systematically assess the differences in associations of plasma omega-3 and omega-6 fatty acid (FA) status with all-cause mortality when plasma FA status is expressed in absolute concentrations versus relative levels. In a community sample of 564 women aged 25-75 years in Queensland, Australia, baseline plasma phospholipid FA levels were measured using gas chromatography. Specific FAs analysed were eicosapentaenoic acid, docosapentaenoic acid, docosahexaenoic acid, total long-chain omega-3 FAs, linoleic acid, arachidonic acid, and total omega-6 FAs. Levels of each FA were expressed in absolute amounts (µg/mL) and relative levels (% of total FAs) and divided into thirds. Deaths were monitored for 17 years and hazard ratios and 95% confidence intervals calculated to assess risk of death according to absolute versus relative plasma FA levels. In total 81 (14%) women died during follow-up. Agreement between absolute and relative measures of plasma FAs was higher in omega-3 than omega-6 FAs. The results of multivariate analyses for risk of all-cause mortality were generally similar with risk tending to inverse associations with plasma phospholipid omega-3 FAs and no association with omega-6 FAs. Sensitivity analyses examining effects of age and presence of serious medical conditions on risk of mortality did not alter findings. The directions and magnitude of associations with mortality of absolute versus relative FA levels were comparable. However, plasma FA expressed as absolute concentrations may be preferred for ease of comparison and since relative units can be deduced from absolute units.

  1. Absolute quantification of pharmacokinetic distribution of RES colloids in individuals with normal liver function

    International Nuclear Information System (INIS)

    Herzog, H.; Spohr, G.; Notohamiprodjo, G.; Feinendegen, L.E.

    1987-01-01

    Estimates of the radiation dose resulting from liver-spleen scintigraphy 99 TCsup(m)-labelled colloids are based on pharmacokinetic data mainly determined in animals. The aim of this study was to check the pharmacokinetic data by direct, absolute in vivo quantification in man. Liver and spleen activities were directly measured using a double-energy window technique. Activities in other organs were quantified by conjugate whole-body scans. All measurement procedures were checked using the whole-body Alderson phantom. Pharmacokinetic data for sulphur colloid, tin colloid, human serum albumin (HSA) millimicrospheres, and phytate were obtained in 13 to 20 normal subjects for each type of colloid. Depending on the colloid type liver uptake was between 54 and 75% of the total administered dose (TAD) and spleen uptake was 3.5 to 21% TAD. Activity measured in blood, urine, lung and thyroid proved to be far from negligible. The results of this work suggest a correction of the animal-based data of colloid distribution and radiation dose on the basis of the direct measurement of absolute uptake in man. (author)

  2. Absolute counting of neutrophils in whole blood using flow cytometry.

    Science.gov (United States)

    Brunck, Marion E G; Andersen, Stacey B; Timmins, Nicholas E; Osborne, Geoffrey W; Nielsen, Lars K

    2014-12-01

    Absolute neutrophil count (ANC) is used clinically to monitor physiological dysfunctions such as myelosuppression or infection. In the research laboratory, ANC is a valuable measure to monitor the evolution of a wide range of disease states in disease models. Flow cytometry (FCM) is a fast, widely used approach to confidently identify thousands of cells within minutes. FCM can be optimised for absolute counting using spiked-in beads or by measuring the sample volume analysed. Here we combine the 1A8 antibody, specific for the mouse granulocyte protein Ly6G, with flow cytometric counting in straightforward FCM assays for mouse ANC, easily implementable in the research laboratory. Volumetric and Trucount™ bead assays were optimized for mouse neutrophils, and ANC values obtained with these protocols were compared to ANC measured by a dual-platform assay using the Orphee Mythic 18 veterinary haematology analyser. The single platform assays were more precise with decreased intra-assay variability compared with ANC obtained using the dual protocol. Defining ANC based on Ly6G expression produces a 15% higher estimate than the dual protocol. Allowing for this difference in ANC definition, the flow cytometry counting assays using Ly6G can be used reliably in the research laboratory to quantify mouse ANC from a small volume of blood. We demonstrate the utility of the volumetric protocol in a time-course study of chemotherapy induced neutropenia using four drug regimens. © 2014 International Society for Advancement of Cytometry.

  3. The chronological age estimation of third molar mineralization of Han population in southwestern China.

    Science.gov (United States)

    Qing, Maofeng; Qiu, Lihua; Gao, Zhi; Bhandari, Kishor

    2014-05-01

    The purpose of the study was to estimate the chronology of third molar mineralization in Han population of southwestern China and find its unique characteristics so that it would provide a reference in several legal cases like forensic age estimation. The study used Demirjian's staging method to study 2192 orthopantomograms of 984 male and 1208 female subjects aged between 8 and 25 years. The statistical data was analyzed by Student's t test and ANOVA. The conclusions of the study are: (1) The chronological mineralization age of third molars of Han population in Southwestern China is similar to the Turkish and the Japanese, was earlier than the Austrian and Han of South China, but later than the Spanish. (2) The mineralization timing of the third molars between two sides in maxilla or mandible has no significant differences in the same gender group. (3) There is no significant difference in mineralization of third molars between male and female, except for tooth 48 in Demirjian's stage E. (4) The mineralization of third molar in maxilla is earlier than mandible. Copyright © 2014 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  4. Identification and age estimation of blood stains on colored backgrounds by near infrared spectroscopy

    NARCIS (Netherlands)

    Edelman, Gerda; Manti, Vicky; van Ruth, Saskia M.; van Leeuwen, Ton; Aalders, Maurice

    2012-01-01

    Non-destructive identification and subsequent age estimation of blood stains are significant steps in forensic casework. The latter can provide important information on the temporal aspects of a crime. As previously shown, visible spectroscopy of blood stains on white backgrounds can successfully be

  5. Some things ought never be done: moral absolutes in clinical ethics.

    Science.gov (United States)

    Pellegrino, Edmund D

    2005-01-01

    Moral absolutes have little or no moral standing in our morally diverse modern society. Moral relativism is far more palatable for most ethicists and to the public at large. Yet, when pressed, every moral relativist will finally admit that there are some things which ought never be done. It is the rarest of moral relativists that will take rape, murder, theft, child sacrifice as morally neutral choices. In general ethics, the list of those things that must never be done will vary from person to person. In clinical ethics, however, the nature of the physician-patient relationship is such that certain moral absolutes are essential to the attainment of the good of the patient - the end of the relationship itself. These are all derivatives of the first moral absolute of all morality: Do good and avoid evil. In the clinical encounter, this absolute entails several subsidiary absolutes - act for the good of the patient, do not kill, keep promises, protect the dignity of the patient, do not lie, avoid complicity with evil. Each absolute is intrinsic to the healing and helping ends of the clinical encounter.

  6. Age differences in emotional reactions: arousal and age-relevance count.

    Science.gov (United States)

    Streubel, Berit; Kunzmann, Ute

    2011-12-01

    Recent findings suggest positivity effects in older adults' attention and memory, but few studies have examined such effects on the level of emotional reactivity. In this study, 52 young and 52 older adults rated 172 pictures of the International Affective Picture System, differing in arousal and age-relevance, in terms of valence and discrete emotions. Age differences in the ratio of pleasantness reactions to pleasant pictures vs. unpleasantness reactions to unpleasant pictures as well as age differences in absolute levels of unpleasantness and pleasantness reactions suggest that positivity effects in older adults' subjective emotional reactions are reduced under high arousal. There is also evidence that positivity effects may be restricted to stimuli with low relevance in old age.

  7. Age estimation by modified Demirjian's method (2004) and its applicability in Tibetan young adults: A digital panoramic study.

    Science.gov (United States)

    Bijjaragi, Shobha C; Sangle, Varsha A; Saraswathi, F K; Patil, Veerendra S; Ashwini Rani, S R; Bapure, Sunil K

    2015-01-01

    Estimation of the age is a procedure adopted by anthropologists, archeologists and forensic scientists. Different methods have been undertaken. However none of them meet the standards as Demirjian's method since 1973. Various researchers have applied this method, in both original and modified form (Chaillet and Demirjian in 2004) in different ethnic groups and the results obtained were not satisfactory. To determine the applicability and accuracy of modified Demirjian's method of dental age estimation (AE) in 8-18 year old Tibetan young adults to evaluate the interrelationship between dental and chronological age and the reliability between intra- and inter observer relationship. Clinical setting and computerized design. A total of 300 Tibetan young adults with an age range from 8 to 18 years were recruited in the study. Digital panoramic radiographs (DPRs) were evaluated as per the modified Demirjian's method (2004). Pearson correlation, paired t-test, linear regression analysis. Inter -and intraobserver reliability revealed a strong agreement. A positive and strong association was found between chronological age and estimated dental age (r = 0.839) with P < 0.01. Modified Demirjian method (2004) overestimated the age by 0.04 years (2.04 months)in Tibetan young adults. Results suggest that, the modified Demirjian method of AE is not suitable for Tibetan young adults. Further studies: With larger sample size and comparision with different methods of AE in a given population would be an interesting area for future research.

  8. Relativistic Absolutism in Moral Education.

    Science.gov (United States)

    Vogt, W. Paul

    1982-01-01

    Discusses Emile Durkheim's "Moral Education: A Study in the Theory and Application of the Sociology of Education," which holds that morally healthy societies may vary in culture and organization but must possess absolute rules of moral behavior. Compares this moral theory with current theory and practice of American educators. (MJL)

  9. Age, Sex and Stature Estimation from Footprint Dimensions

    Directory of Open Access Journals (Sweden)

    Paurbhi Singh

    2017-04-01

    Full Text Available Objectives: The present study was carried out to evaluate the utility and reliability of footprint dimensions in age, sex and stature determination in the North Indian population. Materials and Methods: This study was carried out using a sample of 400 people (146 female and 254 male aged 10-65 years in Uttar Pradesh, North Western state of India. Footprints of both feet were taken bilaterally, and thus a total of 800 prints were obtained. A cluster of 7 measurements were taken carefully with the help of a scientific scale ruler. Five measurements were length dimensions from the most anterior part of the toe (T1–T5 to the mid rear heel point and two were breadth dimensions from both left and right footprints: breadth at ball (BBAL, breadth at heel (BHEL and 2 indexes: heel-ball Index (HBI and footprint index (FPI. All data were analyzed statistically using Student’s t-test, regression coefficient and Pearson’s correlation for the estimation of sex on the basis of footprint dimensions. Results: The T1 in left footprints was greater than right footprints in males, while T1 and BBAL were both found to be greater in left footprints than right footprints in females. All the seven foot dimensions were higher in males than females. Conclusion: There were statistically significant differences observed in all footprint dimensions between the male and female footprints except LFPI, LHBI, and RHBI.

  10. Resting-state oscillatory activity in children born small for gestational age: a magnetoencephalographic study

    Directory of Open Access Journals (Sweden)

    Maria eBoersma

    2013-09-01

    Full Text Available Growth restriction in utero during a period that is critical for normal growth of the brain, has previously been associated with deviations in cognitive abilities and brain anatomical and functional changes. We measured magnetoencephalography (MEG in 4-7 year old children to test if children born small for gestational age (SGA show deviations in resting-state brain oscillatory activity. Children born SGA children with postnatally spontaneous catch-up growth (SGA+; 6 boys, 7 girls; mean age 6.3 y (SD=0.9 and children born appropriate for gestational age (AGA; 7 boys, 3 girls; mean age 6.0 y (SD=1.2 participated in a resting-state MEG study. We calculated absolute and relative power spectra and used nonparametric statistics to test for group differences. SGA+ and AGA born children showed no significant differences in absolute and relative power except for reduced absolute gamma band power in SGA children. At time of MEG investigation, SGA+ children showed was significantly lower head circumference (HC and a trend toward lower IQ, however there was no association of HC or IQ with absolute or relative power. Except for reduced absolute gamma band power, our findings suggest normal brain activity patterns at school age in a group of children born SGA in which spontaneous catch-up growth of bodily length after birth occurred. Although previous findings suggest that being born SGA alters brain oscillatory activity early in neonatal life, we show that these neonatal alterations do not persist at early school age when spontaneous postnatal catch-up growth occurs after birth.

  11. Normative perceptual estimates for 91 healthy subjects age 60-75: Impact of age, education, employment, physical exercise, alcohol and video gaming

    Directory of Open Access Journals (Sweden)

    Inge Linda Wilms

    2014-10-01

    Full Text Available Visual perception serves as the basis for much of the higher level cognitive processing as well as human activity in general. Here we present normative estimates for the following components of visual perception: the visual perceptual threshold, the visual short-term memory capacity and the visual perceptual encoding/decoding speed (processing speed of Visual Short-Term Memory (VSTM based on an assessment of 91 healthy subjects aged 60-75. The estimates were modelled from input from a whole-report assessment based on A Theory of Visual Attention (TVA. In addition to the estimates themselves, we present correlational data, and multiple regression analyses between the estimates and self-reported demographic data and lifestyle variables. The regression statistics suggest that education level, video gaming activity and employment status may significantly impact the encoding/decoding speed of VTSM but not the capacity of VSTM nor the visual perceptual threshold. The estimates will be useful for future studies into the effects of various types of intervention and training on cognition in general and visual attention in particular.

  12. Orthopantomographic evaluation of canine and first premolar using Demirjian's stages in central India: new approach to forensic age estimation.

    Science.gov (United States)

    Pathak, Hrishikesh V; Dixit, Pradeep; Shrigiriwar, Manish; Bardale, Rajesh

    2012-07-01

    Teeth development is widely used for age estimation in forensic science. The aims of this study were as follows: first, to establish Indian data on canine and first premolar development for age estimation and second, to investigate population differences in teeth development. Orthopantomograms of 340 Indian children aged between 5 and 14 years were analyzed. Demirjian's stages were recorded for the developmental evaluation of canine and first premolar and for further descriptive statistical analysis. A two-way ANOVA was performed to test the significance of difference in teeth development by sex and stage. A one-way ANOVA was performed to investigate population differences in teeth development. Results showed statistically significant differences in teeth development by sex and stage. Accordingly, teeth development was earlier in girls. No statistically significant differences were observed in timings of Demirjian's stages among different populations. In conclusion, the findings of this study could be used for age estimation of Indian children. © 2012 American Academy of Forensic Sciences.

  13. Multivariate methods for the analysis of complex and big data in forensic sciences. Application to age estimation in living persons.

    Science.gov (United States)

    Lefèvre, Thomas; Chariot, Patrick; Chauvin, Pierre

    2016-09-01

    Researchers handle increasingly higher dimensional datasets, with many variables to explore. Such datasets pose several problems, since they are difficult to handle and present unexpected features. As dimensionality increases, classical statistical analysis becomes inoperative. Variables can present redundancy, and the reduction of dataset dimensionality to its lowest possible value is often needed. Principal components analysis (PCA) has proven useful to reduce dimensionality but present several shortcomings. As others, forensic sciences will face the issues specific related to an evergrowing quantity of data to be integrated. Age estimation in living persons, an unsolved problem so far, could benefit from the integration of various sources of data, e.g., clinical, dental and radiological data. We present here novel multivariate techniques (nonlinear dimensionality reduction techniques, NLDR), applied to a theoretical example. Results were compared to those of PCA. NLDR techniques were then applied to clinical, dental and radiological data (13 variables) used for age estimation. The correlation dimension of these data was estimated. NLDR techniques outperformed PCA results. They showed that two living persons sharing similar characteristics may present rather different estimated ages. Moreover, data presented a very high informational redundancy, i.e., a correlation dimension of 2. NLDR techniques should be used with or preferred to PCA techniques to analyze complex and big data. Data routinely used for age estimation may not be considered suitable for this purpose. How integrating other data or approaches could improve age estimation in living persons is still uncertain. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  14. Using Gait Dynamics to Estimate Load from a Body-Worn Accelerometer

    Science.gov (United States)

    2016-02-05

    dynamics, ambulation, correlation structure, musculoskeletal injury I. INTRODUCTION ilitary personnel commonly engage in training and operational...according to their load estimation accuracy, which is defined by the Pearson correlation , r, of its load estimates with the true loads (see Tables...method. In Table IV are shown the mean absolute error, MAE, and Pearson correlation , r, of the load estimates using estimates from GS alone, PLS alone

  15. Three-dimensional analysis of third molar development to estimate age of majority.

    Science.gov (United States)

    Márquez-Ruiz, Ana Belén; Treviño-Tijerina, María Concepción; González-Herrera, Lucas; Sánchez, Belén; González-Ramírez, Amanda Rocío; Valenzuela, Aurora

    2017-09-01

    Third molars are one of the few biological markers available for age estimation in undocumented juveniles close the legal age of majority, assuming an age of 18years as the most frequent legal demarcation between child and adult status. To obtain more accurate visualization and evaluation of third molar mineralization patterns from computed tomography images, a new software application, DentaVol©, was developed. Third molar mineralization according to qualitative (Demirjian's maturational stage) and quantitative parameters (third molar volume) of dental development was assessed in multi-slice helical computed tomography images of both maxillary arches displayed by DentaVol© from 135 individuals (62 females and 73 males) aged between 14 and 23years. Intra- and inter-observer agreement values were remarkably high for both evaluation procedures and for all third molars. A linear correlation between third molar mineralization and chronological age was found, with third molar maturity occurring earlier in males than in females. Assessment of dental development with both procedures, by using DentaVol© software, can be considered a good indicator of age of majority (18years or older) in all third molars. Our results indicated that virtual computed tomography imaging can be considered a valid alternative to orthopantomography for evaluations of third molar mineralization, and therefore a complementary tool for determining the age of majority. Copyright © 2017 The Chartered Society of Forensic Sciences. Published by Elsevier B.V. All rights reserved.

  16. Effekten af absolut kumulation

    DEFF Research Database (Denmark)

    Kyvsgaard, Britta; Klement, Christian

    2012-01-01

    Som led i finansloven for 2011 blev regeringen og forligspartierne enige om at undersøge reglerne om strafudmåling ved samtidig pådømmelse af flere kriminelle forhold og i forbindelse hermed vurdere konsekvenserne af at ændre de gældende regler i forhold til kapacitetsbehovet i Kriminalforsorgens...... samlet bødesum ved en absolut kumulation i forhold til en modereret kumulation, som nu er gældende....

  17. Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers

    DEFF Research Database (Denmark)

    Schmidt, Marjanka K; Hogervorst, Frans; van Hien, Richard R

    2016-01-01

    PURPOSE: CHEK2*1100delC is a well-established breast cancer risk variant that is most prevalent in European populations; however, there are limited data on risk of breast cancer by age and tumor subtype, which limits its usefulness in breast cancer risk prediction. We aimed to generate tumor...... subtype- and age-specific risk estimates by using data from the Breast Cancer Association Consortium, including 44,777 patients with breast cancer and 42,997 controls from 33 studies genotyped for CHEK2*1100delC. PATIENTS AND METHODS: CHEK2*1100delC genotyping was mostly done by a custom Taqman assay....... Breast cancer odds ratios (ORs) for CHEK2*1100delC carriers versus noncarriers were estimated by using logistic regression and adjusted for study (categorical) and age. Main analyses included patients with invasive breast cancer from population- and hospital-based studies. RESULTS: Proportions...

  18. Some absolutely effective product methods

    Directory of Open Access Journals (Sweden)

    H. P. Dikshit

    1992-01-01

    Full Text Available It is proved that the product method A(C,1, where (C,1 is the Cesàro arithmetic mean matrix, is totally effective under certain conditions concerning the matrix A. This general result is applied to study absolute Nörlund summability of Fourier series and other related series.

  19. Yarkovsky effect and V-shapes: New method to compute family ages

    Science.gov (United States)

    Spoto, F.; Milani, A.; Cellino, A.; Knezevic, Z.; Novakovic, B.; Paolicchi, P.

    2014-07-01

    The computation of family ages is a high-priority goal. As a matter of principle, it can be achieved by using V-shape plots for the families old enough to have the Yarkovsky effect dominating the spread of the proper a and large enough for a statistically significant analysis of the shape. By performing an asteroid family classification with a very enlarged dataset, the results are not just ''more families'', but there are interesting qualitative changes. These are due to the large-number statistics, but also to the larger fraction of smaller objects contained in recently numbered asteroids. We are convinced that our method is effective in adding many smaller asteroids to the core families. As a result, we have a large number of families with very well defined V-shapes, thus with a good possibility of age estimation. We have developed our method to compute ages, which we believe is better than those used previously because it is more objective. Since there are no models for error in absolute magnitude H and for albedo, we have also developed a model of the error in the inverse of the diameter and then we have performed a weighted least-squares fit. We report at least 5/6 examples of dynamical families for which the computation of the V-shape is possible. These examples show the presence of different internal structure of the families, e.g., in the dynamical family of (4) Vesta, we have found two collisional families. The main problem in estimating the ages is the calibration. The difficulty in the Yarkovsky calibration, due to the need to extrapolate from near-Earth asteroids (NEAs) with measured da/dt to main-belt asteroids, is in most cases the main limitation to the accuracy of the age estimation. We obtain an age estimation by scaling the results for the NEA for which there is the best Yarkovsky effect determination, namely (101955) Bennu.

  20. Absolute measurement method of environment radon content

    International Nuclear Information System (INIS)

    Ji Changsong

    1989-11-01

    A portable environment radon content device with a 40 liter decay chamber based on the method of Thomas double filter radon content absolute measurement has been developed. The correctness of the method of Thomas double filter absolute measurement has been verified by the experiments to measure the sampling gas density of radon that the theoretical density has been known. In addition, the intrinsic uncertainty of this method is also determined in the experiments. The confidence of this device is about 95%, the sensitivity is better than 0.37 Bqm -3 and the intrinsic uncertainty is less than 10%. The results show that the selected measuring and structure parameters are reasonable and the experimental methods are acceptable. In this method, the influence on the measured values from the radioactive equilibrium of radon and its daughters, the ratio of combination daughters to the total daughters and the fraction of charged particles has been excluded in the theory and experimental methods. The formula of Thomas double filter absolute measuring radon is applicable to the cylinder decay chamber, and the applicability is also verified when the diameter of exit filter is much smaller than the diameter of inlet filter

  1. Age dependence of rat liver function measurements

    DEFF Research Database (Denmark)

    Fischer-Nielsen, A; Poulsen, H E; Hansen, B A

    1989-01-01

    Changes in the galactose elimination capacity, the capacity of urea-N synthesis and antipyrine clearance were studied in male Wistar rats at the age of 8, 20 and 44 weeks. Further, liver tissue concentrations of microsomal cytochrome P-450, microsomal protein and glutathione were measured. All...... liver function measurements increased from the age of 8 to 44 weeks when expressed in absolute values. In relation to body weight, these function measurements were unchanged or reduced from week 8 to week 20. At week 44, galactose elimination capacity and capacity of urea-N synthesis related to body...... weight were increased by 10% and 36%, respectively, and antipyrine plasma clearance was reduced to 50%. Liver tissue concentrations of microsomal cytochrome P-450 and microsomal protein increased with age when expressed in absolute values, but were unchanged per g liver, i.e., closely related to liver...

  2. Probabilistic performance estimators for computational chemistry methods: The empirical cumulative distribution function of absolute errors

    Science.gov (United States)

    Pernot, Pascal; Savin, Andreas

    2018-06-01

    Benchmarking studies in computational chemistry use reference datasets to assess the accuracy of a method through error statistics. The commonly used error statistics, such as the mean signed and mean unsigned errors, do not inform end-users on the expected amplitude of prediction errors attached to these methods. We show that, the distributions of model errors being neither normal nor zero-centered, these error statistics cannot be used to infer prediction error probabilities. To overcome this limitation, we advocate for the use of more informative statistics, based on the empirical cumulative distribution function of unsigned errors, namely, (1) the probability for a new calculation to have an absolute error below a chosen threshold and (2) the maximal amplitude of errors one can expect with a chosen high confidence level. Those statistics are also shown to be well suited for benchmarking and ranking studies. Moreover, the standard error on all benchmarking statistics depends on the size of the reference dataset. Systematic publication of these standard errors would be very helpful to assess the statistical reliability of benchmarking conclusions.

  3. Study on absolute humidity influence of NRL-1 measuring apparatus for radon

    International Nuclear Information System (INIS)

    Shan Jian; Xiao Detao; Zhao Guizhi; Zhou Qingzhi; Liu Yan; Qiu Shoukang; Meng Yecheng; Xiong Xinming; Liu Xiaosong; Ma Wenrong

    2014-01-01

    The absolute humidity and temperature's effects on the NRL-1 measuring apparatus for radon were studied in this paper. By controlling the radon activity concentration of the radon laboratory in University of South China and improving the temperature and humidity adjust strategy, different correction factor values under different absolute humidities were obtained. Moreover, a correction curve between 1.90 and 14.91 g/m"3 was also attained. The results show that in the case of absolute humidity, when it is less than 2.4 g/m"3, collection efficiency of the NRL-1 measuring apparatus for radon tends to be constant, and the correction factor of the absolute humidity closes to 1. However, the correction factor increases nonlinearly along with the absolute humidity. (authors)

  4. On the possibilities of age estimation of iron ore minerals using the Moessbauer effect

    International Nuclear Information System (INIS)

    Mbesherubusa, F.

    1980-01-01

    The age of geological iron are samples from regions with mainly oxidative conditions has been estimated, by the method of Moessbauer spectroscopy. In many cases the relative age of two samples could be determined unambigiously, due to the different Moessbauer data for Fe 2 + and Fe 3 + and the superparamagnetic behaviour of the iron oxide microcrystallites (up to about 200 A). This has been proved by three series of measurements with samples from three different climatic zones - Baja California, West-Australia, and Rhine Valley. (orig./HBR) [de

  5. A combined method to estimate the appropriate age value of closed uraniun-lead system

    International Nuclear Information System (INIS)

    Malakhov, S.S.

    1982-01-01

    A new method is proposed for obtaining the appropriate age values of closed uranium-lead systems taking into account total indeependent information delivered as a result of spectral and isotope-lead analyses. A simple mathematical apparatus which permits to perform a geochronological interpretation of samples using miniature computers is considered and suggested. A simple estimation formula for determining the age of uranium-lead systems under the assumption of model development of isotope ratios of ordinary lead is derived and tested basing on the facts

  6. Application of third molar development and eruption models in estimating dental age in Malay sub-adults.

    Science.gov (United States)

    Mohd Yusof, Mohd Yusmiaidil Putera; Cauwels, Rita; Deschepper, Ellen; Martens, Luc

    2015-08-01

    The third molar development (TMD) has been widely utilized as one of the radiographic method for dental age estimation. By using the same radiograph of the same individual, third molar eruption (TME) information can be incorporated to the TMD regression model. This study aims to evaluate the performance of dental age estimation in individual method models and the combined model (TMD and TME) based on the classic regressions of multiple linear and principal component analysis. A sample of 705 digital panoramic radiographs of Malay sub-adults aged between 14.1 and 23.8 years was collected. The techniques described by Gleiser and Hunt (modified by Kohler) and Olze were employed to stage the TMD and TME, respectively. The data was divided to develop three respective models based on the two regressions of multiple linear and principal component analysis. The trained models were then validated on the test sample and the accuracy of age prediction was compared between each model. The coefficient of determination (R²) and root mean square error (RMSE) were calculated. In both genders, adjusted R² yielded an increment in the linear regressions of combined model as compared to the individual models. The overall decrease in RMSE was detected in combined model as compared to TMD (0.03-0.06) and TME (0.2-0.8). In principal component regression, low value of adjusted R(2) and high RMSE except in male were exhibited in combined model. Dental age estimation is better predicted using combined model in multiple linear regression models. Copyright © 2015 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  7. The impact of case definition on attention-deficit/hyperactivity disorder prevalence estimates in community-based samples of school-aged children.

    Science.gov (United States)

    McKeown, Robert E; Holbrook, Joseph R; Danielson, Melissa L; Cuffe, Steven P; Wolraich, Mark L; Visser, Susanna N

    2015-01-01

    To determine the impact of varying attention-deficit/hyperactivity disorder (ADHD) diagnostic criteria, including new DSM-5 criteria, on prevalence estimates. Parent and teacher reports identified high- and low-screen children with ADHD from elementary schools in 2 states that produced a diverse overall sample. The parent interview stage included the Diagnostic Interview Schedule for Children-IV (DISC-IV), and up to 4 additional follow-up interviews. Weighted prevalence estimates, accounting for complex sampling, quantified the impact of varying ADHD criteria using baseline and the final follow-up interview data. At baseline 1,060 caregivers were interviewed; 656 had at least 1 follow-up interview. Teachers and parents reported 6 or more ADHD symptoms for 20.5% (95% CI = 18.1%-23.2%) and 29.8% (CI = 24.5%-35.6%) of children respectively, with criteria for impairment and onset by age 7 years (DSM-IV) reducing these proportions to 16.3% (CI = 14.7%-18.0%) and 17.5% (CI = 13.3%-22.8%); requiring at least 4 teacher-reported symptoms reduced the parent-reported prevalence to 8.9% (CI = 7.4%-10.6%). Revising age of onset to 12 years per DSM-5 increased the 8.9% estimate to 11.3% (CI = 9.5%-13.3%), with a similar increase seen at follow-up: 8.2% with age 7 onset (CI = 5.9%-11.2%) versus 13.0% (CI = 7.6%-21.4%) with onset by age 12. Reducing the number of symptoms required for those aged 17 and older increased the overall estimate to 13.1% (CI = 7.7%-21.5%). These findings quantify the impact on prevalence estimates of varying case definition criteria for ADHD. Further research of impairment ratings and data from multiple informants is required to better inform clinicians conducting diagnostic assessments. DSM-5 changes in age of onset and number of symptoms required for older adolescents appear to increase prevalence estimates, although the full impact is uncertain due to the age of our sample. Published by Elsevier Inc.

  8. Human dental age estimation using third molar developmental stages: does a Bayesian approach outperform regression models to discriminate between juveniles and adults?

    OpenAIRE

    Thevissen, P. W.; FIEUWS, Steffen; Willems, G.

    2010-01-01

    Dental age estimation methods based on the radiologically detected third molar developmental stages are implemented in forensic age assessments to discriminate between juveniles and adults considering the judgment of young unaccompanied asylum seekers. Accurate and unbiased age estimates combined with appropriate quantified uncertainties are the required properties for accurate forensic reporting. In this study, a subset of 910 individuals uniformly distributed in age between 16 and 22 years ...

  9. Genomic DNA-based absolute quantification of gene expression in Vitis.

    Science.gov (United States)

    Gambetta, Gregory A; McElrone, Andrew J; Matthews, Mark A

    2013-07-01

    Many studies in which gene expression is quantified by polymerase chain reaction represent the expression of a gene of interest (GOI) relative to that of a reference gene (RG). Relative expression is founded on the assumptions that RG expression is stable across samples, treatments, organs, etc., and that reaction efficiencies of the GOI and RG are equal; assumptions which are often faulty. The true variability in RG expression and actual reaction efficiencies are seldom determined experimentally. Here we present a rapid and robust method for absolute quantification of expression in Vitis where varying concentrations of genomic DNA were used to construct GOI standard curves. This methodology was utilized to absolutely quantify and determine the variability of the previously validated RG ubiquitin (VvUbi) across three test studies in three different tissues (roots, leaves and berries). In addition, in each study a GOI was absolutely quantified. Data sets resulting from relative and absolute methods of quantification were compared and the differences were striking. VvUbi expression was significantly different in magnitude between test studies and variable among individual samples. Absolute quantification consistently reduced the coefficients of variation of the GOIs by more than half, often resulting in differences in statistical significance and in some cases even changing the fundamental nature of the result. Utilizing genomic DNA-based absolute quantification is fast and efficient. Through eliminating error introduced by assuming RG stability and equal reaction efficiencies between the RG and GOI this methodology produces less variation, increased accuracy and greater statistical power. © 2012 Scandinavian Plant Physiology Society.

  10. Absolutely minimal extensions of functions on metric spaces

    International Nuclear Information System (INIS)

    Milman, V A

    1999-01-01

    Extensions of a real-valued function from the boundary ∂X 0 of an open subset X 0 of a metric space (X,d) to X 0 are discussed. For the broad class of initial data coming under discussion (linearly bounded functions) locally Lipschitz extensions to X 0 that preserve localized moduli of continuity are constructed. In the set of these extensions an absolutely minimal extension is selected, which was considered before by Aronsson for Lipschitz initial functions in the case X 0 subset of R n . An absolutely minimal extension can be regarded as an ∞-harmonic function, that is, a limit of p-harmonic functions as p→+∞. The proof of the existence of absolutely minimal extensions in a metric space with intrinsic metric is carried out by the Perron method. To this end, ∞-subharmonic, ∞-superharmonic, and ∞-harmonic functions on a metric space are defined and their properties are established

  11. Absolute measurement of 152Eu

    International Nuclear Information System (INIS)

    Baba, Hiroshi; Baba, Sumiko; Ichikawa, Shinichi; Sekine, Toshiaki; Ishikawa, Isamu

    1981-08-01

    A new method of the absolute measurement for 152 Eu was established based on the 4πβ-γ spectroscopic anti-coincidence method. It is a coincidence counting method consisting of a 4πβ-counter and a Ge(Li) γ-ray detector, in which the effective counting efficiencies of the 4πβ-counter for β-rays, conversion electrons, and Auger electrons were obtained by taking the intensity ratios for certain γ-rays between the single spectrum and the spectrum coincident with the pulses from the 4πβ-counter. First, in order to verify the method, three different methods of the absolute measurement were performed with a prepared 60 Co source to find excellent agreement among the results deduced by them. Next, the 4πβ-γ spectroscopic coincidence measurement was applied to 152 Eu sources prepared by irradiating an enriched 151 Eu target in a reactor. The result was compared with that obtained by the γ-ray spectrometry using a 152 Eu standard source supplied by LMRI. They agreed with each other within the error of 2%. (author)

  12. Absolute carrier phase effects in the two-color excitation of dipolar molecules

    International Nuclear Information System (INIS)

    Brown, Alex; Meath, W.J.; Kondo, A.E.

    2002-01-01

    The pump-probe excitation of a two-level dipolar (d≠0) molecule, where the pump frequency is tuned to the energy level separation while the probe frequency is extremely small, is examined theoretically as an example of absolute phase control of excitation processes. The state populations depend on the probe field's absolute carrier phase but are independent of the pump field's absolute carrier phase. Interestingly, the absolute phase effects occur for pulse durations much longer and field intensities much weaker than those required to see such effects in single pulse excitation

  13. THE ABSOLUTE MAGNITUDE OF RRc VARIABLES FROM STATISTICAL PARALLAX

    International Nuclear Information System (INIS)

    Kollmeier, Juna A.; Burns, Christopher R.; Thompson, Ian B.; Preston, George W.; Crane, Jeffrey D.; Madore, Barry F.; Morrell, Nidia; Prieto, José L.; Shectman, Stephen; Simon, Joshua D.; Villanueva, Edward; Szczygieł, Dorota M.; Gould, Andrew; Sneden, Christopher; Dong, Subo

    2013-01-01

    We present the first definitive measurement of the absolute magnitude of RR Lyrae c-type variable stars (RRc) determined purely from statistical parallax. We use a sample of 242 RRc variables selected from the All Sky Automated Survey for which high-quality light curves, photometry, and proper motions are available. We obtain high-resolution echelle spectra for these objects to determine radial velocities and abundances as part of the Carnegie RR Lyrae Survey. We find that M V,RRc = 0.59 ± 0.10 at a mean metallicity of [Fe/H] = –1.59. This is to be compared with previous estimates for RRab stars (M V,RRab = 0.76 ± 0.12) and the only direct measurement of an RRc absolute magnitude (RZ Cephei, M V,RRc = 0.27 ± 0.17). We find the bulk velocity of the halo relative to the Sun to be (W π , W θ , W z ) = (12.0, –209.9, 3.0) km s –1 in the radial, rotational, and vertical directions with dispersions (σ W π ,σ W θ ,σ W z ) = (150.4, 106.1, 96.0) km s -1 . For the disk, we find (W π , W θ , W z ) = (13.0, –42.0, –27.3) km s –1 relative to the Sun with dispersions (σ W π ,σ W θ ,σ W z ) = (67.7,59.2,54.9) km s -1 . Finally, as a byproduct of our statistical framework, we are able to demonstrate that UCAC2 proper-motion errors are significantly overestimated as verified by UCAC4

  14. Determination of absolute detection efficiencies for detectors of interest in homeland security

    International Nuclear Information System (INIS)

    Ayaz-Maierhafer, Birsen; DeVol, Timothy A.

    2007-01-01

    The absolute total and absolute peak detection efficiencies of gamma ray detector materials NaI:Tl, CdZnTe, HPGe, HPXe, LaBr 3 :Ce and LaCl 3 :Ce were simulated and compared to that of polyvinyltoluene (PVT). The dimensions of the PVT detector were 188.82 cmx60.96 cmx5.08 cm, which is a typical size for a single-panel portal monitor. The absolute total and peak detection efficiencies for these detector materials for the point, line and spherical source geometries of 60 Co (1332 keV), 137 Cs (662 keV) and 241 Am (59.5 keV) were simulated at various source-to-detector distances using the Monte Carlo N-Particle software (MCNP5-V1.30). The comparison of the absolute total detection efficiencies for a point, line and spherical source geometry of 60 Co and 137 Cs at different source-to-detector distance showed that the absolute detection efficiency for PVT is higher relative to the other detectors of typical dimensions for that material. However, the absolute peak detection efficiency of some of these detectors are higher relative to PVT, for example the absolute peak detection efficiency of NaI:Tl (7.62 cm diameterx7.62 cm long), HPGe (7.62 cm diameterx7.62 cm long), HPXe (11.43 cm diameterx60.96 cm long), and LaCl 3 :Ce (5.08 cm diameterx5.08 cm long) are all greater than that of a 188.82 cmx60.96 cmx5.08 cm PVT detector for 60 Co and 137 Cs for all geometries studied. The absolute total and absolute peak detection efficiencies of a right circular cylinder of NaI:Tl with various diameters and thicknesses were determined for a point source. The effect of changing the solid angle on the NaI:Tl detectors showed that with increasing solid angle and detector thickness, the absolute efficiency increases. This work establishes a common basis for differentiating detector materials for passive portal monitoring of gamma ray radiation

  15. UNBIASED MOMENT-RATE SPECTRA AND ABSOLUTE SITE EFFECTS IN THE KACHCHH BASIN, INDIA, FROM THE ANALYSIS OF THE AFTERSHOCKS OF THE 2001 Mw 7.6 BHUJ EARTHQUAKE

    Energy Technology Data Exchange (ETDEWEB)

    Malagnini, L; Bodin, P; Mayeda, K; Akinci, A

    2005-05-04

    What can be learned about absolute site effects on ground motions and about earthquake source spectra from recordings at temporary seismic stations, none of which could be considered a 'reference' (hard rock) site, for which no geotechnical information is available, in a very poorly instrumented region? This challenge motivated our current study of aftershocks of the 2001 Mw 7.6 Bhuj earthquake, in Western India. Crustal attenuation and spreading relationships based on the same data used here were determined in an earlier study. In this paper we decouple the ambiguity between absolute source radiation and site effects by first computing robust estimates of moment-rate spectra of about 200 aftershocks in each of two depth ranges. Using these new estimates of sourcespectra, and our understanding of regional wave propagation, we extract the absolute site terms of the sites of the temporary deployment. Absolute site terms (one for each component of the ground motion, for each station) are computed in an average sense, via an L{sub 1}-norm minimization, and results for each site are averaged over wide ranges of azimuths and takeoff angles. The Bhuj deployment is characterized by a variable shallow geology, mostly of soft sedimentary units. Vertical site terms in the region were observed to be almost featureless and slightly < 1.0 within wide frequency ranges. As a result, H/V spectral ratios mimic the absolute behaviors of absolute horizontal site terms, and they generally overpredict them. On the contrary, with respect to the results for sedimentary rock sites (limestone, dolomite) obtained by Malagnini et al. (2004), H/V spectral ratios in their study did not have much in common with absolute horizontal site terms. Spectral ratios between the vector sum of the computed horizontal site terms for the temporary deployment with respect to the same quantity computed at the hardest rock station available, BAC1, are seriously biased by its non-flat, non

  16. Incremental lines in root cementum of human teeth: An approach to their role in age estimation using polarizing microscopy

    Directory of Open Access Journals (Sweden)

    Aggarwal Pooja

    2008-01-01

    Full Text Available Age estimation is an important factor in the identification of an individual in forensic science. The hard tissues of the human dentition are able to resist decay and degradation long after other tissues are lost. This resistance has made teeth useful indicators for age calculation. Recent research indicates that tooth cementum annulations (TCA may be used more reliably than any other morphological or histological traits of the adult skeleton for age estimation. The purpose of this study was to examine the correlation between age and the number of incremental lines in human dental cementum and to ascertain the best method of studying cementum with respect to different forms of microscopy. Thirty nonrestorable teeth were extracted from 20 people, and longitudinal ground section of each tooth was prepared. Photomicrographs of the area at the junction of apical and middle third of the root under light and polarized microscope were taken. The cementum was composed of multiple light and dark bands that were counted on the photomicrograph with the help of image analysis software and added to the average eruption time of individual tooth. The predicted age of the individual was thus obtained. Results showed a significant correlation between the predicted age and actual chronological age of the individual. These data indicate that quantitation of cementum annuli is a moderately reliable means for age estimation in humans and polarizing microscopy is a better means of visualizing incremental lines of cementum compared to light microscopy.

  17. Estimation of the aging grade of T91 steel by laser-induced breakdown spectroscopy coupled with support vector machines

    Science.gov (United States)

    Lu, Shengzi; Dong, Meirong; Huang, Jianwei; Li, Wenbing; Lu, Jidong; Li, Jun

    2018-02-01

    T91 steel is a representative martensitic heat-resistant steel widely used in high temperature compression components of industrial equipment. During the service period, the operation safety and the service life of the equipment will be affected by the change of structure and mechanical properties of the steel components, which is called material aging. In order to develop a rapid in-situ aging estimation technology of high temperature compression components surface, laser-induced breakdown spectroscopy (LIBS) coupled with support vector machine (SVM) was employed in this paper. The spectral characteristics of 10 T91 steel specimens with different aging grades were analyzed. Line intensities and the line intensity ratios (ionic/atomic and alloying element/matrix element) that indicate the change of metallographic structure were used to establish SVM models, and the results using different variable sets were compared. The model was optimized by comparing different pulse number for practical effectiveness, and the robustness of the model was investigated in dealing with the inhomogeneity of steel composition. The study results show that the estimation model obtained the best performance using line intensities and line intensity ratios averaged from 31st-60th laser pulses as input variables. The estimation accuracy of validation set was greatly improved from 75.8% to 95.3%. In addition, the model showed the outstanding capacity for handling the fluctuations of spectral signals between measuring-points (spots), which indicated that the aging estimation based on a few measuring-points is feasible. The studies presented here demonstrate that the LIBS coupled with SVM is a new useful technique for the aging estimation of steel, and would be well-suited for fast safety assessment in industrial field.

  18. Estimated inventory of plutonium and uranium radionuclides for vegetation in aged fallout areas

    International Nuclear Information System (INIS)

    Romney, E.M.; Gilbert, R.O.; Wallace, A.; Kinnear, J.

    1976-02-01

    Data are presented on the contamination of vegetation by 239 Pu, 240 Pu, and other radionuclides in aged fallout areas on the Nevada Test Site (NTS) and the Tonopah Test Range (TTR). Comparisons of soil and vegetation inventory estimates indicate that the standing vegetation contributes an insignificant portion of the total amount of 239-240 Pu present in these aged fallout areas. The amounts of Pu available for vegetation-transport to animals grazing on-site would appear to be relatively small in comparison to the total amounts deposited upon soil. Findings indicate that most of the contaminant found on vegetation probably is attributable to resuspendable materials

  19. Absolute decay parametric instability of high-temperature plasma

    International Nuclear Information System (INIS)

    Zozulya, A.A.; Silin, V.P.; Tikhonchuk, V.T.

    1986-01-01

    A new absolute decay parametric instability having wide spatial localization region is shown to be possible near critical plasma density. Its excitation is conditioned by distributed feedback of counter-running Langmuir waves occurring during parametric decay of incident and reflected pumping wave components. In a hot plasma with the temperature of the order of kiloelectronvolt its threshold is lower than that of a known convective decay parametric instability. Minimum absolute instability threshold is shown to be realized under conditions of spatial parametric resonance of higher orders

  20. The age estimation practice related to illegal unaccompanied minors immigration in Italy.

    Science.gov (United States)

    Pradella, F; Pinchi, V; Focardi, M; Grifoni, R; Palandri, M; Norelli, G A

    2017-12-01

    The migrants arrived to the Italian coasts in 2016 were 181.436, 18% more than the previous year and 6% more than the highest number ever since. An "unaccompanied minor" (UAM) is a third-country national or a stateless person under eighteen years of age, who arrives on the territory of the Member State unaccompanied by an adult responsible for him/her whether by law or by the practice of the Member State concerned, and for as long as he or she is not effectively taken into the care of such a person; it includes a minor who is left unaccompanied after he/she entered the territory of the Member States. As many as 95.985 UAMs applied for international protection in an EU member country just in 2015, almost four times the number registered in the previous year. The UAMs arrived in Italy were 28.283 in 2016; 94% of them were males, 92% unaccompanied, 8% of them under 15; the 53,6% is 17; the individuals between 16 and 17 are instead the 82%. Many of them (50%), 6561 in 2016, escaped from the sanctuaries, thus avoiding to be formally identified and registered in Italy in the attempt to reach more easily northern Europe countries, since The Dublin Regulations (2003) state that the asylum application should be held in the EU country of entrance or where parents reside. The age assessment procedures can therefore be considered as a relevant task that weighs in on the shoulders of the forensic experts with all the related issues and the coming of age is the important threshold. In the EU laws on asylum, the minors are considered as one of the groups of vulnerable persons towards whom Member States have specific obligations. A proper EU common formal regulation in the matter of age estimation procedures still lacks. According to the Italian legal framework in the matter, a medical examination should have been always performed but a new law completely changed the approach to the procedures of age estimation of the migrant (excluding the criminal cases) with a better adherence

  1. Confidence-Accuracy Calibration in Absolute and Relative Face Recognition Judgments

    Science.gov (United States)

    Weber, Nathan; Brewer, Neil

    2004-01-01

    Confidence-accuracy (CA) calibration was examined for absolute and relative face recognition judgments as well as for recognition judgments from groups of stimuli presented simultaneously or sequentially (i.e., simultaneous or sequential mini-lineups). When the effect of difficulty was controlled, absolute and relative judgments produced…

  2. Intra- and inter-observer reproducibility study of gestational age estimation using three common foetal biometric parameters: Experienced versus inexperienced sonographer

    International Nuclear Information System (INIS)

    Ohagwu, C.C.; Onoduagu, H.I.; Eze, C.U.; Ochie, K.; Ohagwu, C.I.

    2015-01-01

    Aim: To assess reproducibility of estimating gestational age (GA) of foetus using femur length (FL), biparietal diameter (BPD) and abdominal circumference (AC) within experienced and inexperienced sonographers and between the two. Patients and methods: Two sets of GA estimates each were obtained for FL, BPD and AC by the two observers in 20 normal singleton foetuses. The first estimates for the three biometric parameters were made by the experienced sonographer. Subsequently, the inexperienced sonographer, blind to the estimates of the first observer obtained his own estimates for the same biometric parameters. After a time interval of ten minutes the process was repeated for the second set of GA estimates. All the gestational age estimates were made following standard protocol. Statistical analysis was performed by Pearson's and intraclass correlations, coefficient of variation and Bland–Altman plots. Statistical inferences were drawn at p < 0.05. Results: The Pearson's and intraclass correlations of between GA estimates within and between both observers from measurement of FL, BPD and AC were very high and statistically significant (p < 0.05). Coefficient of variation for duplicate measurements for GA estimates within observers and between observers were quite negligible. Between observers, the first and second GA estimates from FL measurements showed the least variation. Estimates from BPD and AC measurements showed greater degree of variation between the observers. Conclusion: Reproducibility of GA estimation using FL, BPD and AC within experienced and inexperienced sonographers and between the two was excellent. Therefore, a fresh Nigerian radiography graduate with adequate exposure in obstetric ultrasound can correctly determine the gestational age of foetus in routine obstetric ultrasound without supervision

  3. Age-specific effective doses for pediatric MSCT examinations at a large children's hospital using DLP conversion coefficients: a simple estimation method

    International Nuclear Information System (INIS)

    Thomas, Karen E.; Wang, Bo

    2008-01-01

    There is a need for an easily accessible method for effective dose estimation in pediatric CT. To estimate effective doses for a variety of pediatric neurological and body CT examinations in five age groups using recently published age- and region-specific dose length product (DLP) to effective dose conversion coefficients. A retrospective review was performed of 1,431 consecutive CT scans over a 12-week period using age- and weight-adjusted CT protocols. Age- and region-specific DLP to effective dose conversion coefficients were applied to console-displayed DLP data. Effective dose estimates for single-phase head CT scans in neonatal, and 1-, 5-, 10- and 15-year-old age groups were 4.2, 3.6, 2.4, 2.0 and 1.4 mSv, respectively. For abdomen/pelvis CT scans the corresponding effective doses were 13.1, 11.1, 8.4, 8.9 and 5.9 mSv. The range of pediatric CT effective doses is wide, from ultralow dose protocols (<1 mSv) to extended-coverage body examinations (10-15 mSv). Age- and region-specific pediatric DLP to effective dose conversion coefficients provide an accessible and user-friendly method for estimating pediatric CT effective doses that is available to radiologists working without medical physics support. (orig.)

  4. Geostatistical Model-Based Estimates of Schistosomiasis Prevalence among Individuals Aged ≤20 Years in West Africa

    Science.gov (United States)

    Schur, Nadine; Hürlimann, Eveline; Garba, Amadou; Traoré, Mamadou S.; Ndir, Omar; Ratard, Raoult C.; Tchuem Tchuenté, Louis-Albert; Kristensen, Thomas K.; Utzinger, Jürg; Vounatsou, Penelope

    2011-01-01

    Background Schistosomiasis is a water-based disease that is believed to affect over 200 million people with an estimated 97% of the infections concentrated in Africa. However, these statistics are largely based on population re-adjusted data originally published by Utroska and colleagues more than 20 years ago. Hence, these estimates are outdated due to large-scale preventive chemotherapy programs, improved sanitation, water resources development and management, among other reasons. For planning, coordination, and evaluation of control activities, it is essential to possess reliable schistosomiasis prevalence maps. Methodology We analyzed survey data compiled on a newly established open-access global neglected tropical diseases database (i) to create smooth empirical prevalence maps for Schistosoma mansoni and S. haematobium for individuals aged ≤20 years in West Africa, including Cameroon, and (ii) to derive country-specific prevalence estimates. We used Bayesian geostatistical models based on environmental predictors to take into account potential clustering due to common spatially structured exposures. Prediction at unobserved locations was facilitated by joint kriging. Principal Findings Our models revealed that 50.8 million individuals aged ≤20 years in West Africa are infected with either S. mansoni, or S. haematobium, or both species concurrently. The country prevalence estimates ranged between 0.5% (The Gambia) and 37.1% (Liberia) for S. mansoni, and between 17.6% (The Gambia) and 51.6% (Sierra Leone) for S. haematobium. We observed that the combined prevalence for both schistosome species is two-fold lower in Gambia than previously reported, while we found an almost two-fold higher estimate for Liberia (58.3%) than reported before (30.0%). Our predictions are likely to overestimate overall country prevalence, since modeling was based on children and adolescents up to the age of 20 years who are at highest risk of infection. Conclusion/Significance We

  5. Auditory working memory predicts individual differences in absolute pitch learning.

    Science.gov (United States)

    Van Hedger, Stephen C; Heald, Shannon L M; Koch, Rachelle; Nusbaum, Howard C

    2015-07-01

    Absolute pitch (AP) is typically defined as the ability to label an isolated tone as a musical note in the absence of a reference tone. At first glance the acquisition of AP note categories seems like a perceptual learning task, since individuals must assign a category label to a stimulus based on a single perceptual dimension (pitch) while ignoring other perceptual dimensions (e.g., loudness, octave, instrument). AP, however, is rarely discussed in terms of domain-general perceptual learning mechanisms. This is because AP is typically assumed to depend on a critical period of development, in which early exposure to pitches and musical labels is thought to be necessary for the development of AP precluding the possibility of adult acquisition of AP. Despite this view of AP, several previous studies have found evidence that absolute pitch category learning is, to an extent, trainable in a post-critical period adult population, even if the performance typically achieved by this population is below the performance of a "true" AP possessor. The current studies attempt to understand the individual differences in learning to categorize notes using absolute pitch cues by testing a specific prediction regarding cognitive capacity related to categorization - to what extent does an individual's general auditory working memory capacity (WMC) predict the success of absolute pitch category acquisition. Since WMC has been shown to predict performance on a wide variety of other perceptual and category learning tasks, we predict that individuals with higher WMC should be better at learning absolute pitch note categories than individuals with lower WMC. Across two studies, we demonstrate that auditory WMC predicts the efficacy of learning absolute pitch note categories. These results suggest that a higher general auditory WMC might underlie the formation of absolute pitch categories for post-critical period adults. Implications for understanding the mechanisms that underlie the

  6. Calibrating the absolute amplitude scale for air showers measured at LOFAR

    International Nuclear Information System (INIS)

    Nelles, A.; Hörandel, J. R.; Karskens, T.; Krause, M.; Corstanje, A.; Enriquez, J. E.; Falcke, H.; Rachen, J. P.; Rossetto, L.; Schellart, P.; Buitink, S.; Erdmann, M.; Krause, R.; Haungs, A.; Hiller, R.; Huege, T.; Link, K.; Schröder, F. G.; Norden, M. J.; Scholten, O.

    2015-01-01

    Air showers induced by cosmic rays create nanosecond pulses detectable at radio frequencies. These pulses have been measured successfully in the past few years at the LOw-Frequency ARray (LOFAR) and are used to study the properties of cosmic rays. For a complete understanding of this phenomenon and the underlying physical processes, an absolute calibration of the detecting antenna system is needed. We present three approaches that were used to check and improve the antenna model of LOFAR and to provide an absolute calibration of the whole system for air shower measurements. Two methods are based on calibrated reference sources and one on a calibration approach using the diffuse radio emission of the Galaxy, optimized for short data-sets. An accuracy of 19% in amplitude is reached. The absolute calibration is also compared to predictions from air shower simulations. These results are used to set an absolute energy scale for air shower measurements and can be used as a basis for an absolute scale for the measurement of astronomical transients with LOFAR

  7. Estimating power capability of aged lithium-ion batteries in presence of communication delays

    Science.gov (United States)

    Fridholm, Björn; Wik, Torsten; Kuusisto, Hannes; Klintberg, Anton

    2018-04-01

    Efficient control of electrified powertrains requires accurate estimation of the power capability of the battery for the next few seconds into the future. When implemented in a vehicle, the power estimation is part of a control loop that may contain several networked controllers which introduces time delays that may jeopardize stability. In this article, we present and evaluate an adaptive power estimation method that robustly can handle uncertain health status and time delays. A theoretical analysis shows that stability of the closed loop system can be lost if the resistance of the model is under-estimated. Stability can, however, be restored by filtering the estimated power at the expense of slightly reduced bandwidth of the signal. The adaptive algorithm is experimentally validated in lab tests using an aged lithium-ion cell subject to a high power load profile in temperatures from -20 to +25 °C. The upper voltage limit was set to 4.15 V and the lower voltage limit to 2.6 V, where significant non-linearities are occurring and the validity of the model is limited. After an initial transient when the model parameters are adapted, the prediction accuracy is within ± 2 % of the actually available power.

  8. New design and facilities for the International Database for Absolute Gravity Measurements (AGrav): A support for the Establishment of a new Global Absolute Gravity Reference System

    Science.gov (United States)

    Wziontek, Hartmut; Falk, Reinhard; Bonvalot, Sylvain; Rülke, Axel

    2017-04-01

    After about 10 years of successful joint operation by BGI and BKG, the International Database for Absolute Gravity Measurements "AGrav" (see references hereafter) was under a major revision. The outdated web interface was replaced by a responsive, high level web application framework based on Python and built on top of Pyramid. Functionality was added, like interactive time series plots or a report generator and the interactive map-based station overview was updated completely, comprising now clustering and the classification of stations. Furthermore, the database backend was migrated to PostgreSQL for better support of the application framework and long-term availability. As comparisons of absolute gravimeters (AG) become essential to realize a precise and uniform gravity standard, the database was extended to document the results on international and regional level, including those performed at monitoring stations equipped with SGs. By this it will be possible to link different AGs and to trace their equivalence back to the key comparisons under the auspices of International Committee for Weights and Measures (CIPM) as the best metrological realization of the absolute gravity standard. In this way the new AGrav database accommodates the demands of the new Global Absolute Gravity Reference System as recommended by the IAG Resolution No. 2 adopted in Prague 2015. The new database will be presented with focus on the new user interface and new functionality, calling all institutions involved in absolute gravimetry to participate and contribute with their information to built up a most complete picture of high precision absolute gravimetry and improve its visibility. A Digital Object Identifier (DOI) will be provided by BGI to contributors to give a better traceability and facilitate the referencing of their gravity surveys. Links and references: BGI mirror site : http://bgi.obs-mip.fr/data-products/Gravity-Databases/Absolute-Gravity-data/ BKG mirror site: http

  9. Absolute Transition Probabilities from the 453.1 keV Level in 183W

    International Nuclear Information System (INIS)

    Malmskog, S.G.

    1966-10-01

    The half life of the 453.1 keV level in 183 W has been measured by the delayed coincidence method to 18.4 ± 0.5 nsec. This determines twelve absolute M1 and E2 transition probabilities, out of which nine are K-forbidden. All transition probabilities are compared with the single particle estimate. The three K-allowed E2, ΔK = 2 transition rates to the 1/2 - (510) rotational band are furthermore compared with the Nilsson model. An attempt to give a quantitative explanation of the observed transition rates has been made by including the effects from admixtures into the single particle wave functions

  10. Absolute cross sections from the ''boomerang model'' for resonant electron-molecule scattering

    International Nuclear Information System (INIS)

    Dube, L.; Herzenberg, A.

    1979-01-01

    The boomerang model is used to calculate absolute cross sections near the 2 Pi/sub g/ shape resonance in e-N 2 scattering. The calculated cross sections are shown to satisfy detailed balancing. The exchange of electrons is taken into account. A parametrized complex-potential curve for the intermediate N 2 /sup ts-/ ion is determined from a small part of the experimental data, and then used to calculate other properties. The calculations are in good agreement with the absolute cross sections for vibrational excitation from the ground state, the absolute cross section v = 1 → 2, and the absolute total cross section

  11. Decision-model estimation of the age-specific disability weight for schistosomiasis japonica: a systematic review of the literature.

    Directory of Open Access Journals (Sweden)

    Julia L Finkelstein

    2008-03-01

    Full Text Available Schistosomiasis is among the most prevalent parasitic infections worldwide. However, current Global Burden of Disease (GBD disability-adjusted life year estimates indicate that its population-level impact is negligible. Recent studies suggest that GBD methodologies may significantly underestimate the burden of parasitic diseases, including schistosomiasis. Furthermore, strain-specific disability weights have not been established for schistosomiasis, and the magnitude of human disease burden due to Schistosoma japonicum remains controversial. We used a decision model to quantify an alternative disability weight estimate of the burden of human disease due to S. japonicum. We reviewed S. japonicum morbidity data, and constructed decision trees for all infected persons and two age-specific strata, or =15 y. We conducted stochastic and probabilistic sensitivity analyses for each model. Infection with S. japonicum was associated with an average disability weight of 0.132, with age-specific disability weights of 0.098 ( or =15 y. Re-estimated disability weights were seven to 46 times greater than current GBD measures; no simulations produced disability weight estimates lower than 0.009. Nutritional morbidities had the greatest contribution to the S. japonicum disability weight in the <15 y model, whereas major organ pathologies were the most critical variables in the older age group. GBD disability weights for schistosomiasis urgently need to be revised, and species-specific disability weights should be established. Even a marginal increase in current estimates would result in a substantial rise in the estimated global burden of schistosomiasis, and have considerable implications for public health prioritization and resource allocation for schistosomiasis research, monitoring, and control.

  12. Absolute and relative reliability of isokinetic and isometric trunk strength testing using the IsoMed-2000 dynamometer.

    Science.gov (United States)

    Roth, Ralf; Donath, Lars; Kurz, Eduard; Zahner, Lukas; Faude, Oliver

    2017-03-01

    The present study aimed to assess the between day reliability of isokinetic and isometric peak torque (PT) during trunk measurement on an isokinetic device (IsoMed 2000). Test-retest-protocol on five separate days. Fifteen healthy sport students (8 female and 7 male) aged 21 to 26. PT was assessed in isometric back extension and flexion as well as right and left rotation. Isokinetic strength was captured at a speed of 60°/s and 150°/s for all tasks. For none of the assessed parameters a meaningful variation in PT during test days was observed. Relative reliability (ICC = 0.85-0.96) was excellent for all tasks. Estimates of absolute reliability as Coefficient of Variation (CoV) and Standard Error of Measurement (SEM in Nm/kg lean body mass) remained stable for isometric (6.9% strength measurement in flexion and extension or trunk rotation in either isometric or isokinetic condition is highly reliable. Therefore, it seems possible to elucidate changes which are smaller than 10% due to intervention programs when a preceding familiarization condition was applied. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. A highly accurate absolute gravimetric network for Albania, Kosovo and Montenegro

    Science.gov (United States)

    Ullrich, Christian; Ruess, Diethard; Butta, Hubert; Qirko, Kristaq; Pavicevic, Bozidar; Murat, Meha

    2016-04-01

    The objective of this project is to establish a basic gravity network in Albania, Kosovo and Montenegro to enable further investigations in geodetic and geophysical issues. Therefore the first time in history absolute gravity measurements were performed in these countries. The Norwegian mapping authority Kartverket is assisting the national mapping authorities in Kosovo (KCA) (Kosovo Cadastral Agency - Agjencia Kadastrale e Kosovës), Albania (ASIG) (Autoriteti Shtetëror i Informacionit Gjeohapësinor) and in Montenegro (REA) (Real Estate Administration of Montenegro - Uprava za nekretnine Crne Gore) in improving the geodetic frameworks. The gravity measurements are funded by Kartverket. The absolute gravimetric measurements were performed from BEV (Federal Office of Metrology and Surveying) with the absolute gravimeter FG5-242. As a national metrology institute (NMI) the Metrology Service of the BEV maintains the national standards for the realisation of the legal units of measurement and ensures their international equivalence and recognition. Laser and clock of the absolute gravimeter were calibrated before and after the measurements. The absolute gravimetric survey was carried out from September to October 2015. Finally all 8 scheduled stations were successfully measured: there are three stations located in Montenegro, two stations in Kosovo and three stations in Albania. The stations are distributed over the countries to establish a gravity network for each country. The vertical gradients were measured at all 8 stations with the relative gravimeter Scintrex CG5. The high class quality of some absolute gravity stations can be used for gravity monitoring activities in future. The measurement uncertainties of the absolute gravity measurements range around 2.5 micro Gal at all stations (1 microgal = 10-8 m/s2). In Montenegro the large gravity difference of 200 MilliGal between station Zabljak and Podgorica can be even used for calibration of relative gravimeters

  14. Grip Strength as an Indicator of Health-Related Quality of Life in Old Age-A Pilot Study.

    Science.gov (United States)

    Musalek, Christina; Kirchengast, Sylvia

    2017-11-24

    Over the last century life expectancy has increased dramatically nearly all over the world. This dramatic absolute and relative increase of the old aged people component of the population has influenced not only population structure but also has dramatic implications for the individuals and public health services. The aim of the present pilot study was to examine the impact of physical well-being assessed by hand grip strength and social factors estimated by social contact frequency on health-related quality of life among 22 men and 41 women ranging in age between 60 and 94 years. Physical well-being was estimated by hand grip strength, data concerning subjective wellbeing and health related quality of life were collected by personal interviews based on the WHOQOL-BREF questionnaires. Number of offspring and intergenerational contacts were not related significantly to health-related quality of life, while social contacts with non-relatives and hand grip strength in contrast had a significant positive impact on health related quality of life among old aged men and women. Physical well-being and in particular muscle strength-estimated by grip strength-may increase health-related quality of life and is therefore an important source for well-being during old age. Grip strength may be used as an indicator of health-related quality of life.

  15. Absolute and relative dosimetry for ELIMED

    Energy Technology Data Exchange (ETDEWEB)

    Cirrone, G. A. P.; Schillaci, F.; Scuderi, V. [INFN, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania, Italy and Institute of Physics Czech Academy of Science, ELI-Beamlines project, Na Slovance 2, Prague (Czech Republic); Cuttone, G.; Candiano, G.; Musumarra, A.; Pisciotta, P.; Romano, F. [INFN, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania (Italy); Carpinelli, M. [INFN Sezione di Cagliari, c/o Dipartimento di Fisica, Università di Cagliari, Cagliari (Italy); Leonora, E.; Randazzo, N. [INFN-Sezione di Catania, Via Santa Sofia 64, Catania (Italy); Presti, D. Lo [INFN-Sezione di Catania, Via Santa Sofia 64, Catania, Italy and Università di Catania, Dipartimento di Fisica e Astronomia, Via S. Sofia 64, Catania (Italy); Raffaele, L. [INFN, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania, Italy and INFN-Sezione di Catania, Via Santa Sofia 64, Catania (Italy); Tramontana, A. [INFN, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania, Italy and Università di Catania, Dipartimento di Fisica e Astronomia, Via S. Sofia 64, Catania (Italy); Cirio, R.; Sacchi, R.; Monaco, V. [INFN, Sezione di Torino, Via P.Giuria, 1 10125 Torino, Italy and Università di Torino, Dipartimento di Fisica, Via P.Giuria, 1 10125 Torino (Italy); Marchetto, F.; Giordanengo, S. [INFN, Sezione di Torino, Via P.Giuria, 1 10125 Torino (Italy)

    2013-07-26

    The definition of detectors, methods and procedures for the absolute and relative dosimetry of laser-driven proton beams is a crucial step toward the clinical use of this new kind of beams. Hence, one of the ELIMED task, will be the definition of procedures aiming to obtain an absolute dose measure at the end of the transport beamline with an accuracy as close as possible to the one required for clinical applications (i.e. of the order of 5% or less). Relative dosimetry procedures must be established, as well: they are necessary in order to determine and verify the beam dose distributions and to monitor the beam fluence and the energetic spectra during irradiations. Radiochromic films, CR39, Faraday Cup, Secondary Emission Monitor (SEM) and transmission ionization chamber will be considered, designed and studied in order to perform a fully dosimetric characterization of the ELIMED proton beam.

  16. Age spans of some Indian speleothems

    International Nuclear Information System (INIS)

    Yadava, M.G.; Ramesh, R.; Polyak, V.J.; Asmerom, Y.

    2009-01-01

    In recent years, research on speleothems (minerals growing in caves, i.e. stalactites, stalagmites and flowstones) have shown that these have potential to provide records of past climate and environmental changes. Speleothems have several advantages compared to other high-resolution land archives (e.g., tree rings and lake sediments). Firstly, these are unaffected by natural erosion processes yielding long records of climate variability. Secondly, precise chronology by U-Th mass spectrometry is possible now. Prior to the advent of mass spectrometry (late 1980s), radiocarbon decay method was applied to date young samples (<40 kyr) and U-Th-alpha-counting method was adopted for older samples. In comparison with radiocarbon dates uranium series dates are absolute ages and no calibration is required. In India, palaeoclimate research using speleothem is in infancy, some work has been reported from Himalaya, central India and Peninsular India, with oxygen isotopes being used as monsoon proxy. Five speleothems from four Indian caves have been dated by U- Th method to estimate their ages and growth durations. Results indicate that these grew during various time intervals in Holocene and late Pleistocene

  17. Estimation of the age-specific per-contact probability of Ebola virus transmission in Liberia using agent-based simulations

    Science.gov (United States)

    Siettos, Constantinos I.; Anastassopoulou, Cleo; Russo, Lucia; Grigoras, Christos; Mylonakis, Eleftherios

    2016-06-01

    Based on multiscale agent-based computations we estimated the per-contact probability of transmission by age of the Ebola virus disease (EVD) that swept through Liberia from May 2014 to March 2015. For the approximation of the epidemic dynamics we have developed a detailed agent-based model with small-world interactions between individuals categorized by age. For the estimation of the structure of the evolving contact network as well as the per-contact transmission probabilities by age group we exploited the so called Equation-Free framework. Model parameters were fitted to official case counts reported by the World Health Organization (WHO) as well as to recently published data of key epidemiological variables, such as the mean time to death, recovery and the case fatality rate.

  18. Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?

    International Nuclear Information System (INIS)

    Boas, D A; Strangman, G; Culver, J P; Hoge, R D; Jasdzewski, G; Poldrack, R A; Rosen, B R; Mandeville, J B

    2003-01-01

    We have measured the changes in oxy-haemoglobin and deoxy-haemoglobin in the adult human brain during a brief finger tapping exercise using near-infrared spectroscopy (NIRS). The cerebral metabolic rate of oxygen (CMRO 2 ) can be estimated from these NIRS data provided certain model assumptions. The change in CMRO 2 is related to changes in the total haemoglobin concentration, deoxy-haemoglobin concentration and blood flow. As NIRS does not provide a measure of dynamic changes in blood flow during brain activation, we relied on a Windkessel model that relates dynamic blood volume and flow changes, which has been used previously for estimating CMRO 2 from functional magnetic resonance imaging (fMRI) data. Because of the partial volume effect we are unable to quantify the absolute changes in the local brain haemoglobin concentrations with NIRS and thus are unable to obtain an estimate of the absolute CMRO 2 change. An absolute estimate is also confounded by uncertainty in the flow-volume relationship. However, the ratio of the flow change to the CMRO 2 change is relatively insensitive to these uncertainties. For the finger tapping task, we estimate a most probable flow-consumption ratio ranging from 1.5 to 3 in agreement with previous findings presented in the literature, although we cannot exclude the possibility that there is no CMRO 2 change. The large range in the ratio arises from the large number of model parameters that must be estimated from the data. A more precise estimate of the flow-consumption ratio will require better estimates of the model parameters or flow information, as can be provided by combining NIRS with fMRI

  19. Estimation of legal age using calcification stages of third molars in living individuals.

    Science.gov (United States)

    Streckbein, Philipp; Reichert, Isabelle; Verhoff, Marcel A; Bödeker, Rolf-Hasso; Kähling, Christopher; Wilbrand, Jan-Falco; Schaaf, Heidrun; Howaldt, Hans-Peter; May, Andreas

    2014-12-01

    The increased number of adolescents and young adults with unknown or inaccurately given date of birth is a current issue in justice and legal medicine. The objective of this study was to determine the extent to which third molar calcification stages assessed on panoramic X-rays could be useful as additional criteria for forensic age estimation in living individuals, focusing on the legally important ages 17 and 18. In a retrospective multi-center study, the developmental stage of each individual's third molar was analyzed using Demirjian's scale in 2360 cases. Additionally, sex, age and ancestry were assessed. Individuals with the lowest calcification stage of all present molars in stage H were ≥18 years with a likelihood of ≥99.05% in the female (n=388), and ≥99.24% in the male (n=482) population. The lowest calcification stage of all present third molars proved to be useful as an additional reliable criterion for the determination of an age ≥18 years. Copyright © 2014 Forensic Science Society. Published by Elsevier Ireland Ltd. All rights reserved.

  20. Philosophy as Inquiry Aimed at the Absolute Knowledge

    Directory of Open Access Journals (Sweden)

    Ekaterina Snarskaya

    2017-09-01

    Full Text Available Philosophy as the absolute knowledge has been studied from two different but closely related approaches: historical and logical. The first approach exposes four main stages in the history of European metaphysics that marked out types of “philosophical absolutism”: the evolution of philosophy brought to light metaphysics of being, method, morals and logic. All of them are associated with the names of Aristotle, Bacon/Descartes, Kant and Hegel. Then these forms are considered in the second approach that defined them as subject-matter of philosophy as such. Due to their overall, comprehensive character, the focus of philosophy on them justifies its claim on absoluteness as far as philosophy is aimed at comprehension of the world’s unity regardless of the philosopher’s background, values and other preferences. And that is its prerogative since no other form of consciousness lays down this kind of aim. Thus, philosophy is defined as an everlasting attempt to succeed in conceiving the world in all its multifold manifestations. This article is to try to clarify the claim of philosophy on the absolute knowledge.

  1. THE ESTIMATION OF STAR FORMATION RATES AND STELLAR POPULATION AGES OF HIGH-REDSHIFT GALAXIES FROM BROADBAND PHOTOMETRY

    International Nuclear Information System (INIS)

    Lee, Seong-Kook; Ferguson, Henry C.; Somerville, Rachel S.; Wiklind, Tommy; Giavalisco, Mauro

    2010-01-01

    We explore methods to improve the estimates of star formation rates and mean stellar population ages from broadband photometry of high-redshift star-forming galaxies. We use synthetic spectral templates with a variety of simple parametric star formation histories to fit broadband spectral energy distributions. These parametric models are used to infer ages, star formation rates, and stellar masses for a mock data set drawn from a hierarchical semi-analytic model of galaxy evolution. Traditional parametric models generally assume an exponentially declining rate of star formation after an initial instantaneous rise. Our results show that star formation histories with a much more gradual rise in the star formation rate are likely to be better templates, and are likely to give better overall estimates of the age distribution and star formation rate distribution of Lyman break galaxies (LBGs). For B- and V-dropouts, we find the best simple parametric model to be one where the star formation rate increases linearly with time. The exponentially declining model overpredicts the age by 100% and 120% for B- and V-dropouts, on average, while for a linearly increasing model, the age is overpredicted by 9% and 16%, respectively. Similarly, the exponential model underpredicts star formation rates by 56% and 60%, while the linearly increasing model underpredicts by 15% and 22%, respectively. For U-dropouts, the models where the star formation rate has a peak (near z ∼ 3) provide the best match for age-overprediction is reduced from 110% to 26%-and star formation rate-underprediction is reduced from 58% to 22%. We classify different types of star formation histories in the semi-analytic models and show how the biases behave for the different classes. We also provide two-band calibration formulae for stellar mass and star formation rate estimations.

  2. U.S. Census Annual Estimates of the Resident Population for Selected Age Groups by Sex for the United States

    Data.gov (United States)

    U.S. Department of Health & Human Services — 2010-2015. U.S. Census Annual Estimates of the Resident Population for Selected Age Groups by Sex for the United States. The estimates are based on the 2010 Census...

  3. Absolute bioavailability of evacetrapib in healthy subjects determined by simultaneous administration of oral evacetrapib and intravenous [13C8]‐evacetrapib as a tracer

    Science.gov (United States)

    Aburub, Aktham; Ward, Chris; Hinds, Chris; Czeskis, Boris; Ruterbories, Kenneth; Suico, Jeffrey G.; Royalty, Jane; Ortega, Demetrio; Pack, Brian W.; Begum, Syeda L.; Annes, William F.; Lin, Qun; Small, David S.

    2015-01-01

    This open‐label, single‐period study in healthy subjects estimated evacetrapib absolute bioavailability following simultaneous administration of a 130‐mg evacetrapib oral dose and 4‐h intravenous (IV) infusion of 175 µg [13C8]‐evacetrapib as a tracer. Plasma samples collected through 168 h were analyzed for evacetrapib and [13C8]‐evacetrapib using high‐performance liquid chromatography/tandem mass spectrometry. Pharmacokinetic parameter estimates following oral and IV doses, including area under the concentration‐time curve (AUC) from zero to infinity (AUC[0‐∞]) and to the last measureable concentration (AUC[0‐tlast]), were calculated. Bioavailability was calculated as the ratio of least‐squares geometric mean of dose‐normalized AUC (oral : IV) and corresponding 90% confidence interval (CI). Bioavailability of evacetrapib was 44.8% (90% CI: 42.2–47.6%) for AUC(0‐∞) and 44.3% (90% CI: 41.8–46.9%) for AUC(0‐tlast). Evacetrapib was well tolerated with no reports of clinically significant safety assessment findings. This is among the first studies to estimate absolute bioavailability using simultaneous administration of an unlabeled oral dose with a 13C‐labeled IV microdose tracer at about 1/1000th the oral dose, with measurement in the pg/mL range. This approach is beneficial for poorly soluble drugs, does not require additional toxicology studies, does not change oral dose pharmacokinetics, and ultimately gives researchers another tool to evaluate absolute bioavailability. PMID:26639670

  4. THE SCHULHOF FAMILY: SOLVING THE AGE PUZZLE

    International Nuclear Information System (INIS)

    Vokrouhlický, David; Ďurech, Josef; Pravec, Petr; Kušnirák, Peter; Hornoch, Kamil; Vraštil, Jan; Krugly, Yurij N.; Inasaridze, Raguli Ya.; Ayvasian, Vova; Zhuzhunadze, Vasili; Molotov, Igor E.; Pray, Donald; Husárik, Marek; Pollock, Joseph T.; Nesvorný, David

    2016-01-01

    The Schulhof family, a tight cluster of small asteroids around the central main belt body (2384) Schulhof, belongs to a so far rare class of very young families (estimated ages less than 1 Myr). Characterization of these asteroid clusters may provide important insights into the physics of the catastrophic disruption of their parent body. The case of the Schulhof family has been up to now complicated by the existence of two proposed epochs of its origin. In this paper, we first use our own photometric observations, as well as archival data, to determine the rotation rate and spin axis orientation of the largest fragment (2384) Schulhof. Our data also allow us to better constrain the absolute magnitude of this asteroid, and thus also improve the determination of its geometric albedo. Next, using the up-to-date catalog of asteroid orbits, we perform a new search of smaller members in the Schulhof family, increasing their number by 50%. Finally, the available data are used to access Schulhof's family age anew. We now find that the younger of the previously proposed two ages of this family is not correct, resulting from a large orbital uncertainty of single-opposition members. Our new runs reveal a single age solution of about 800 kyr with a realistic uncertainty of 200 kyr

  5. The Schulhof Family: Solving the Age Puzzle

    Science.gov (United States)

    Vokrouhlický, David; Ďurech, Josef; Pravec, Petr; Kušnirák, Peter; Hornoch, Kamil; Vraštil, Jan; Krugly, Yurij N.; Inasaridze, Raguli Ya.; Ayvasian, Vova; Zhuzhunadze, Vasili; Molotov, Igor E.; Pray, Donald; Husárik, Marek; Pollock, Joseph T.; Nesvorný, David

    2016-03-01

    The Schulhof family, a tight cluster of small asteroids around the central main belt body (2384) Schulhof, belongs to a so far rare class of very young families (estimated ages less than 1 Myr). Characterization of these asteroid clusters may provide important insights into the physics of the catastrophic disruption of their parent body. The case of the Schulhof family has been up to now complicated by the existence of two proposed epochs of its origin. In this paper, we first use our own photometric observations, as well as archival data, to determine the rotation rate and spin axis orientation of the largest fragment (2384) Schulhof. Our data also allow us to better constrain the absolute magnitude of this asteroid, and thus also improve the determination of its geometric albedo. Next, using the up-to-date catalog of asteroid orbits, we perform a new search of smaller members in the Schulhof family, increasing their number by 50%. Finally, the available data are used to access Schulhof's family age anew. We now find that the younger of the previously proposed two ages of this family is not correct, resulting from a large orbital uncertainty of single-opposition members. Our new runs reveal a single age solution of about 800 kyr with a realistic uncertainty of 200 kyr.

  6. THE SCHULHOF FAMILY: SOLVING THE AGE PUZZLE

    Energy Technology Data Exchange (ETDEWEB)

    Vokrouhlický, David; Ďurech, Josef [Institute of Astronomy, Charles University, V Holešovičkách 2, CZ-18000 Prague 8 (Czech Republic); Pravec, Petr; Kušnirák, Peter; Hornoch, Kamil; Vraštil, Jan [Astronomical Institute, Czech Academy of Sciences, Fričova 298, CZ-251 65 Ondrejov (Czech Republic); Krugly, Yurij N. [Institute of Astronomy of Kharkiv National University, Sumska Str. 35, 61022 Kharkiv (Ukraine); Inasaridze, Raguli Ya.; Ayvasian, Vova; Zhuzhunadze, Vasili [Kharadze Abastumani Astrophysical Observatory, Ilia State University, K. Cholokoshvili Av. 3/5, Tbilisi 0162, Georgia (United States); Molotov, Igor E. [Keldysh Institute of Applied Mathematics, RAS, Miusskaya 4, Moscow 125047 (Russian Federation); Pray, Donald [Sugarloaf Mountain Observatory, South Deerfield, MA 01373 (United States); Husárik, Marek [Astronomical Institute of the Slovak Academy of Sciences, SK-059 60 Tatranska Lomnica (Slovakia); Pollock, Joseph T. [Physics and Astronomy Department, Appalachian State University, 525 Rivers St, Boone, NC 28608 (United States); Nesvorný, David, E-mail: vokrouhl@cesnet.cz [Department of Space Studies, Southwest Research Institute, 1050 Walnut Street, Suite 300, Boulder, CO 80302 (United States)

    2016-03-15

    The Schulhof family, a tight cluster of small asteroids around the central main belt body (2384) Schulhof, belongs to a so far rare class of very young families (estimated ages less than 1 Myr). Characterization of these asteroid clusters may provide important insights into the physics of the catastrophic disruption of their parent body. The case of the Schulhof family has been up to now complicated by the existence of two proposed epochs of its origin. In this paper, we first use our own photometric observations, as well as archival data, to determine the rotation rate and spin axis orientation of the largest fragment (2384) Schulhof. Our data also allow us to better constrain the absolute magnitude of this asteroid, and thus also improve the determination of its geometric albedo. Next, using the up-to-date catalog of asteroid orbits, we perform a new search of smaller members in the Schulhof family, increasing their number by 50%. Finally, the available data are used to access Schulhof's family age anew. We now find that the younger of the previously proposed two ages of this family is not correct, resulting from a large orbital uncertainty of single-opposition members. Our new runs reveal a single age solution of about 800 kyr with a realistic uncertainty of 200 kyr.

  7. Absolute calibration technique for spontaneous fission sources

    International Nuclear Information System (INIS)

    Zucker, M.S.; Karpf, E.

    1984-01-01

    An absolute calibration technique for a spontaneously fissioning nuclide (which involves no arbitrary parameters) allows unique determination of the detector efficiency for that nuclide, hence of the fission source strength

  8. Absolute luminosity measurements with the LHCb detector at the LHC

    CERN Document Server

    Aaij, R; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amhis, Y; Anderson, J; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Arrabito, L; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Bachmann, S; Back, J J; Bailey, D S; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bates, A; Bauer, C; Bauer, Th; Bay, A; Bediaga, I; Belous, K; Belyaev, I; Ben-Haim, E; Benayoun, M; Bencivenni, G; Benson, S; Benton, J; Bernet, R; Bettler, M-O; van Beuzekom, M; Bien, A; Bifani, S; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blanks, C; Blouw, J; Blusk, S; Bobrov, A; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Brisbane, S; Britsch, M; Britton, T; Brook, N H; Brown, H; Büchler-Germann, A; Burducea, I; Bursche, A; Buytaert, J; Cadeddu, S; Caicedo Carvajal, J M; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carson, L; Carvalho Akiba, K; Casse, G; Cattaneo, M; Charles, M; Charpentier, Ph; Chiapolini, N; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Collins, P; Constantin, F; Conti, G; Contu, A; Cook, A; Coombes, M; Corti, G; Cowan, G A; Currie, R; D'Almagne, B; D'Ambrosio, C; David, P; De Bonis, I; De Capua, S; De Cian, M; De Lorenzi, F; De Miranda, J M; De Paula, L; De Simone, P; Decamp, D; Deckenhoff, M; Degaudenzi, H; Deissenroth, M; Del Buono, L; Deplano, C; Deschamps, O; Dettori, F; Dickens, J; Dijkstra, H; Diniz Batista, P; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Dzhelyadin, R; Eames, C; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisele, F; Eisenhardt, S; Ekelhof, R; Eklund, L; Elsasser, Ch; d'Enterria, D G; Esperante Pereira, D; Estève, L; Falabella, A; Fanchini, E; Färber, C; Fardell, G; Farinelli, C; Farry, S; Fave, V; Fernandez Albor, V; Ferro-Luzzi, M; Filippov, S; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Frank, M; Frei, C; Frosini, M; Furcas, S; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garnier, J-C; Garofoli, J; Garra Tico, J; Garrido, L; Gaspar, C; Gauvin, N; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gordon, H; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Gregson, S; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Haefeli, G; Haen, C; Haines, S C; Hampson, T; Hansmann-Menzemer, S; Harji, R; Harnew, N; Harrison, J; Harrison, P F; He, J; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hicks, E; Hofmann, W; Holubyev, K; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Huston, R S; Hutchcroft, D; Hynds, D; Iakovenko, V; Ilten, P; Imong, J; Jacobsson, R; Jaeger, A; Jahjah Hussein, M; Jans, E; Jansen, F; Jaton, P; Jean-Marie, B; Jing, F; John, M; Johnson, D; Jones, C R; Jost, B; Kandybei, S; Karacson, M; Karbach, T M; Keaveney, J; Kerzel, U; Ketel, T; Keune, A; Khanji, B; Kim, Y M; Knecht, M; Koblitz, S; Koppenburg, P; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kruzelecki, K; Kucharczyk, M; Kukulak, S; Kumar, R; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Le Gac, R; van Leerdam, J; Lees, J-P; Lefèvre, R; Leflat, A; Lefrançois, J; Leroy, O; Lesiak, T; Li, L; Li Gioi, L; Lieng, M; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; Lopes, J H; Lopez Asamar, E; Lopez-March, N; Luisier, J; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Magnin, J; Malde, S; Mamunur, R M D; Manca, G; Mancinelli, G; Mangiafave, N; Marconi, U; Märki, R; Marks, J; Martellotti, G; Martens, A; Martin, L; Martín Sánchez, A; Martinez Santos, D; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Matveev, M; Maurice, E; Maynard, B; Mazurov, A; McGregor, G; McNulty, R; Mclean, C; Meissner, M; Merk, M; Merkel, J; Messi, R; Miglioranzi, S; Milanes, D A; Minard, M-N; Monteil, S; Moran, D; Morawski, P; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Musy, M; Mylroie-Smith, J; Naik, P; Nakada, T; Nandakumar, R; Nardulli, J; Nasteva, I; Nedos, M; Needham, M; Neufeld, N; Nguyen-Mau, C; Nicol, M; Nies, S; Niess, V; Nikitin, N; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalora Goicochea, J M; Owen, P; Pal, B; Palacios, J; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Paterson, S K; Patrick, G N; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perego, D L; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pessina, G; Petrella, A; Petrolini, A; Pie Valls, B; Pietrzyk, B; Pilar, T; Pinci, D; Plackett, R; Playfer, S; Plo Casasus, M; Polok, G; Poluektov, A; Polycarpo, E; Popov, D; Popovici, B; Potterat, C; Powell, A; du Pree, T; Prisciandaro, J; Pugatch, V; Puig Navarro, A; Qian, W; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Raven, G; Redford, S; Reid, M M; dos Reis, A C; Ricciardi, S; Rinnert, K; Roa Romero, D A; Robbe, P; Rodrigues, E; Rodrigues, F; Rodriguez Perez, P; Rogers, G J; Roiser, S; Romanovsky, V; Rouvinet, J; Ruf, T; Ruiz, H; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salzmann, C; Sannino, M; Santacesaria, R; Santamarina Rios, C; Santinelli, R; Santovetti, E; Sapunov, M; Sarti, A; Satriano, C; Satta, A; Savrie, M; Savrina, D; Schaack, P; Schiller, M; Schleich, S; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M -H; Schwemmer, R; Sciubba, A; Seco, M; Semennikov, A; Senderowska, K; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shao, B; Shapkin, M; Shapoval, I; Shatalov, P; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Silva Coutinho, R; Skottowe, H P; Skwarnicki, T; Smith, A C; Smith, N A; Sobczak, K; Soler, F J P; Solomin, A; Soomro, F; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Stagni, F; Stahl, S; Steinkamp, O; Stoica, S; Stone, S; Storaci, B; Straticiuc, M; Straumann, U; Styles, N; Subbiah, V K; Swientek, S; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Topp-Joergensen, S; Tran, M T; Tsaregorodtsev, A; Tuning, N; Ubeda Garcia, M; Ukleja, A; Urquijo, P; Uwer, U; Vagnoni, V; Valenti, G; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; Velthuis, J J; Veltri, M; Vervink, K; Viaud, B; Videau, I; Vilasis-Cardona, X; Visniakov, J; Vollhardt, A; Voong, D; Vorobyev, A; Voss, H; Wacker, K; Wandernoth, S; Wang, J; Ward, D R; Webber, A D; Websdale, D; Whitehead, M; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wishahi, J; Witek, M; Witzeling, W; Wotton, S A; Wyllie, K; Xie, Y; Xing, F; Yang, Z; Young, R; Yushchenko, O; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhong, L; Zverev, E; Zvyagin, A

    2012-01-01

    Absolute luminosity measurements are of general interest for colliding-beam experiments at storage rings. These measurements are necessary to determine the absolute cross-sections of reaction processes and are valuable to quantify the performance of the accelerator. LHCb has applied two methods to determine the absolute scale of its luminosity measurements for proton-proton collisions at the LHC with a centre-of-mass energy of 7 TeV. In addition to the classic ``van der Meer scan'' method a novel technique has been developed which makes use of direct imaging of the individual beams using beam-gas and beam-beam interactions. This beam imaging method is made possible by the high resolution of the LHCb vertex detector and the close proximity of the detector to the beams, and allows beam parameters such as positions, angles and widths to be determined. The results of the two methods have comparable precision and are in good agreement. Combining the two methods, an overall precision of 3.5\\% in the absolute lumi...

  9. Absolute calibration of TFTR helium proportional counters

    International Nuclear Information System (INIS)

    Strachan, J.D.; Diesso, M.; Jassby, D.; Johnson, L.; McCauley, S.; Munsat, T.; Roquemore, A.L.; Loughlin, M.

    1995-06-01

    The TFTR helium proportional counters are located in the central five (5) channels of the TFTR multichannel neutron collimator. These detectors were absolutely calibrated using a 14 MeV neutron generator positioned at the horizontal midplane of the TFTR vacuum vessel. The neutron generator position was scanned in centimeter steps to determine the collimator aperture width to 14 MeV neutrons and the absolute sensitivity of each channel. Neutron profiles were measured for TFTR plasmas with time resolution between 5 msec and 50 msec depending upon count rates. The He detectors were used to measure the burnup of 1 MeV tritons in deuterium plasmas, the transport of tritium in trace tritium experiments, and the residual tritium levels in plasmas following 50:50 DT experiments

  10. Absolute determination of radiation bursts and of proportional counters space charge effect through the influence method

    International Nuclear Information System (INIS)

    Rios, I.J.; Mayer, R.E.

    2016-01-01

    When proportional counters are employed in charge integration mode to determine the magnitude of a radiation pulse, so intense that individual detection events take place in a time too short to produce individual output pulses, mostly in pulsed neutron sources, the strong build-up of positive space charge reduces the electric multiplication factor of the proportional detector. Under such conditions the ensuing measurement underestimates the amount of radiation that interacted with the detector. If the geometric characteristics, the filling gas pressure and the voltage applied to that detector are known, it becomes possible to apply an analytical correction method to the measurement. In this article we present a method that allows to determine the absolute value of the detected radiation burst without the need to know the characteristics of the employed detectors. It is necessary to employ more than one detector, taking advantage of the Influence Method. The “Influence Method” is conceived for the absolute determination of a nuclear particle flux in the absence of known detector efficiency and without the need to register coincidences of any kind. This method exploits the influence of the presence of one detector in the count rate of another detector, when they are placed one behind the other and define statistical estimators for the absolute number of incident particles and for the efficiency (Rios and Mayer, 2015 [1,2]). Its practical implementation in the measurement of a moderated neutron flux arising from an isotopic neutron source was exemplified in (Rios and Mayer, 2016 [3]) and the extension for multiple detectors in (Rios and Mayer 2016 [4]). - Highlights: • Absolute determination of radiation burst. • Proportional counters space charge effect. • Radiation measurements on pulsed devices.

  11. THE ABSOLUTE MAGNITUDE OF RRc VARIABLES FROM STATISTICAL PARALLAX

    Energy Technology Data Exchange (ETDEWEB)

    Kollmeier, Juna A.; Burns, Christopher R.; Thompson, Ian B.; Preston, George W.; Crane, Jeffrey D.; Madore, Barry F.; Morrell, Nidia; Prieto, José L.; Shectman, Stephen; Simon, Joshua D.; Villanueva, Edward [Observatories of the Carnegie Institution of Washington, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Szczygieł, Dorota M.; Gould, Andrew [Department of Astronomy, The Ohio State University, 4051 McPherson Laboratory, Columbus, OH 43210 (United States); Sneden, Christopher [Department of Astronomy, University of Texas at Austin, TX 78712 (United States); Dong, Subo [Institute for Advanced Study, 500 Einstein Drive, Princeton, NJ 08540 (United States)

    2013-09-20

    We present the first definitive measurement of the absolute magnitude of RR Lyrae c-type variable stars (RRc) determined purely from statistical parallax. We use a sample of 242 RRc variables selected from the All Sky Automated Survey for which high-quality light curves, photometry, and proper motions are available. We obtain high-resolution echelle spectra for these objects to determine radial velocities and abundances as part of the Carnegie RR Lyrae Survey. We find that M{sub V,RRc} = 0.59 ± 0.10 at a mean metallicity of [Fe/H] = –1.59. This is to be compared with previous estimates for RRab stars (M{sub V,RRab} = 0.76 ± 0.12) and the only direct measurement of an RRc absolute magnitude (RZ Cephei, M{sub V,RRc} = 0.27 ± 0.17). We find the bulk velocity of the halo relative to the Sun to be (W{sub π}, W{sub θ}, W{sub z} ) = (12.0, –209.9, 3.0) km s{sup –1} in the radial, rotational, and vertical directions with dispersions (σ{sub W{sub π}},σ{sub W{sub θ}},σ{sub W{sub z}}) = (150.4, 106.1, 96.0) km s{sup -1}. For the disk, we find (W{sub π}, W{sub θ}, W{sub z} ) = (13.0, –42.0, –27.3) km s{sup –1} relative to the Sun with dispersions (σ{sub W{sub π}},σ{sub W{sub θ}},σ{sub W{sub z}}) = (67.7,59.2,54.9) km s{sup -1}. Finally, as a byproduct of our statistical framework, we are able to demonstrate that UCAC2 proper-motion errors are significantly overestimated as verified by UCAC4.

  12. Estimation of age-specific rates of reactivation and immune boosting of the varicella zoster virus

    Directory of Open Access Journals (Sweden)

    Isabella Marinelli

    2017-06-01

    Full Text Available Studies into the impact of vaccination against the varicella zoster virus (VZV have increasingly focused on herpes zoster (HZ, which is believed to be increasing in vaccinated populations with decreasing infection pressure. This idea can be traced back to Hope-Simpson's hypothesis, in which a person's immune status determines the likelihood that he/she will develop HZ. Immunity decreases over time, and can be boosted by contact with a person experiencing varicella (exogenous boosting or by a reactivation attempt of the virus (endogenous boosting. Here we use transmission models to estimate age-specific rates of reactivation and immune boosting, exogenous as well as endogenous, using zoster incidence data from the Netherlands (2002–2011, n = 7026. The boosting and reactivation rates are estimated with splines, enabling these quantities to be optimally informed by the data. The analyses show that models with high levels of exogenous boosting and estimated or zero endogenous boosting, constant rate of loss of immunity, and reactivation rate increasing with age (to more than 5% per year in the elderly give the best fit to the data. Estimates of the rates of immune boosting and reactivation are strongly correlated. This has important implications as these parameters determine the fraction of the population with waned immunity. We conclude that independent evidence on rates of immune boosting and reactivation in persons with waned immunity are needed to robustly predict the impact of varicella vaccination on the incidence of HZ.

  13. Stimulus Probability Effects in Absolute Identification

    Science.gov (United States)

    Kent, Christopher; Lamberts, Koen

    2016-01-01

    This study investigated the effect of stimulus presentation probability on accuracy and response times in an absolute identification task. Three schedules of presentation were used to investigate the interaction between presentation probability and stimulus position within the set. Data from individual participants indicated strong effects of…

  14. Absolute gravity measurements in California

    Science.gov (United States)

    Zumberge, M. A.; Sasagawa, G.; Kappus, M.

    1986-08-01

    An absolute gravity meter that determines the local gravitational acceleration by timing a freely falling mass with a laser interferometer has been constructed. The instrument has made measurements at 11 sites in California, four in Nevada, and one in France. The uncertainty in the results is typically 10 microgal. Repeated measurements have been made at several of the sites; only one shows a substantial change in gravity.

  15. Relational versus absolute representation in categorization.

    Science.gov (United States)

    Edwards, Darren J; Pothos, Emmanuel M; Perlman, Amotz

    2012-01-01

    This study explores relational-like and absolute-like representations in categorization. Although there is much evidence that categorization processes can involve information about both the particular physical properties of studied instances and abstract (relational) properties, there has been little work on the factors that lead to one kind of representation as opposed to the other. We tested 370 participants in 6 experiments, in which participants had to classify new items into predefined artificial categories. In 4 experiments, we observed a predominantly relational-like mode of classification, and in 2 experiments we observed a shift toward an absolute-like mode of classification. These results suggest 3 factors that promote a relational-like mode of classification: fewer items per group, more training groups, and the presence of a time delay. Overall, we propose that less information about the distributional properties of a category or weaker memory traces for the category exemplars (induced, e.g., by having smaller categories or a time delay) can encourage relational-like categorization.

  16. Calibrated Tully-fisher Relations For Improved Photometric Estimates Of Disk Rotation Velocities

    Science.gov (United States)

    Reyes, Reinabelle; Mandelbaum, R.; Gunn, J. E.; Pizagno, J.

    2011-01-01

    We present calibrated scaling relations (also referred to as Tully-Fisher relations or TFRs) between rotation velocity and photometric quantities-- absolute magnitude, stellar mass, and synthetic magnitude (a linear combination of absolute magnitude and color)-- of disk galaxies at z 0.1. First, we selected a parent disk sample of 170,000 galaxies from SDSS DR7, with redshifts between 0.02 and 0.10 and r band absolute magnitudes between -18.0 and -22.5. Then, we constructed a child disk sample of 189 galaxies that span the parameter space-- in absolute magnitude, color, and disk size-- covered by the parent sample, and for which we have obtained kinematic data. Long-slit spectroscopy were obtained from the Dual Imaging Spectrograph (DIS) at the Apache Point Observatory 3.5 m for 99 galaxies, and from Pizagno et al. (2007) for 95 galaxies (five have repeat observations). We find the best photometric estimator of disk rotation velocity to be a synthetic magnitude with a color correction that is consistent with the Bell et al. (2003) color-based stellar mass ratio. The improved rotation velocity estimates have a wide range of scientific applications, and in particular, in combination with weak lensing measurements, they enable us to constrain the ratio of optical-to-virial velocity in disk galaxies.

  17. A Novel Physiology-Based Mathematical Model to Estimate Red Blood Cell Lifespan in Different Human Age Groups.

    Science.gov (United States)

    An, Guohua; Widness, John A; Mock, Donald M; Veng-Pedersen, Peter

    2016-09-01

    Direct measurement of red blood cell (RBC) survival in humans has improved from the original accurate but limited differential agglutination technique to the current reliable, safe, and accurate biotin method. Despite this, all of these methods are time consuming and require blood sampling over several months to determine the RBC lifespan. For situations in which RBC survival information must be obtained quickly, these methods are not suitable. With the exception of adults and infants, RBC survival has not been extensively investigated in other age groups. To address this need, we developed a novel, physiology-based mathematical model that quickly estimates RBC lifespan in healthy individuals at any age. The model is based on the assumption that the total number of RBC recirculations during the lifespan of each RBC (denoted by N max) is relatively constant for all age groups. The model was initially validated using the data from our prior infant and adult biotin-labeled red blood cell studies and then extended to the other age groups. The model generated the following estimated RBC lifespans in 2-year-old, 5-year-old, 8-year-old, and 10-year-old children: 62, 74, 82, and 86 days, respectively. We speculate that this model has useful clinical applications. For example, HbA1c testing is not reliable in identifying children with diabetes because HbA1c is directly affected by RBC lifespan. Because our model can estimate RBC lifespan in children at any age, corrections to HbA1c values based on the model-generated RBC lifespan could improve diabetes diagnosis as well as therapy in children.

  18. Adaptive Methods for Permeability Estimation and Smart Well Management

    Energy Technology Data Exchange (ETDEWEB)

    Lien, Martha Oekland

    2005-04-01

    The main focus of this thesis is on adaptive regularization methods. We consider two different applications, the inverse problem of absolute permeability estimation and the optimal control problem of estimating smart well management. Reliable estimates of absolute permeability are crucial in order to develop a mathematical description of an oil reservoir. Due to the nature of most oil reservoirs, mainly indirect measurements are available. In this work, dynamic production data from wells are considered. More specifically, we have investigated into the resolution power of pressure data for permeability estimation. The inversion of production data into permeability estimates constitutes a severely ill-posed problem. Hence, regularization techniques are required. In this work, deterministic regularization based on adaptive zonation is considered, i.e. a solution approach with adaptive multiscale estimation in conjunction with level set estimation is developed for coarse scale permeability estimation. A good mathematical reservoir model is a valuable tool for future production planning. Recent developments within well technology have given us smart wells, which yield increased flexibility in the reservoir management. In this work, we investigate into the problem of finding the optimal smart well management by means of hierarchical regularization techniques based on multiscale parameterization and refinement indicators. The thesis is divided into two main parts, where Part I gives a theoretical background for a collection of research papers that has been written by the candidate in collaboration with others. These constitutes the most important part of the thesis, and are presented in Part II. A brief outline of the thesis follows below. Numerical aspects concerning calculations of derivatives will also be discussed. Based on the introduction to regularization given in Chapter 2, methods for multiscale zonation, i.e. adaptive multiscale estimation and refinement

  19. Effect of Absolute From Hibiscus syriacus L. Flower on Wound Healing in Keratinocytes

    Science.gov (United States)

    Yoon, Seok Won; Lee, Kang Pa; Kim, Do-Yoon; Hwang, Dae Il; Won, Kyung-Jong; Lee, Dae Won; Lee, Hwan Myung

    2017-01-01

    Background: Proliferation and migration of keratinocytes are essential for the repair of cutaneous wounds. Hibiscus syriacus L. has been used in Asian medicine; however, research on keratinocytes is inadequate. Objective: To establish the dermatological properties of absolute from Hibiscus syriacus L. flower (HSF) and to provide fundamental research for alternative medicine. Materials and Methods: We identified the composition of HSF absolute using gas chromatography-mass spectrometry analysis. We also examined the effect of HSF absolute in HaCaT cells using the XTT assay, Boyden chamber assay, sprout-out growth assay, and western blotting. We conducted an in-vivo wound healing assay in rat tail-skin. Results: Ten major active compounds were identified from HSF absolute. As determined by the XTT assay, Boyden chamber assay, and sprout-out growth assay results, HSF absolute exhibited similar effects as that of epidermal growth factor on the proliferation and migration patterns of keratinocytes (HaCaT cells), which were significantly increased after HSF absolute treatment. The expression levels of the phosphorylated signaling proteins relevant to proliferation, including extracellular signal-regulated kinase 1/2 (Erk 1/2) and Akt, were also determined by western blot analysis. Conclusion: These results of our in-vitro and ex-vivo studies indicate that HSF absolute induced cell growth and migration of HaCaT cells by phosphorylating both Erk 1/2 and Akt. Moreover, we confirmed the wound-healing effect of HSF on injury of the rat tail-skin. Therefore, our results suggest that HSF absolute is promising for use in cosmetics and alternative medicine. SUMMARY Hisbiscus syriacus L. flower absolute increases HaCaT cell migration and proliferation.Hisbiscus syriacus L. flower absolute regulates phosphorylation of ERK 1/2 and Akt in HaCaT cell.Treatment with Hisbiscus syriacus L. flower induced sprout outgrowth.The wound in the tail-skin of rat was reduced by Hisbiscus syriacus

  20. Fringe order correction for the absolute phase recovered by two selected spatial frequency fringe projections in fringe projection profilometry.

    Science.gov (United States)

    Ding, Yi; Peng, Kai; Yu, Miao; Lu, Lei; Zhao, Kun

    2017-08-01

    The performance of the two selected spatial frequency phase unwrapping methods is limited by a phase error bound beyond which errors will occur in the fringe order leading to a significant error in the recovered absolute phase map. In this paper, we propose a method to detect and correct the wrong fringe orders. Two constraints are introduced during the fringe order determination of two selected spatial frequency phase unwrapping methods. A strategy to detect and correct the wrong fringe orders is also described. Compared with the existing methods, we do not need to estimate the threshold associated with absolute phase values to determine the fringe order error, thus making it more reliable and avoiding the procedure of search in detecting and correcting successive fringe order errors. The effectiveness of the proposed method is validated by the experimental results.