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Sample records for abnormal doppler enteral

  1. ADEPT - Abnormal Doppler Enteral Prescription Trial

    Directory of Open Access Journals (Sweden)

    McCormick Kenny

    2009-10-01

    Full Text Available Abstract Background Pregnancies complicated by abnormal umbilical artery Doppler blood flow patterns often result in the baby being born both preterm and growth-restricted. These babies are at high risk of milk intolerance and necrotising enterocolitis, as well as post-natal growth failure, and there is no clinical consensus about how best to feed them. Policies of both early milk feeding and late milk feeding are widely used. This randomised controlled trial aims to determine whether a policy of early initiation of milk feeds is beneficial compared with late initiation. Optimising neonatal feeding for this group of babies may have long-term health implications and if either of these policies is shown to be beneficial it can be immediately adopted into clinical practice. Methods and Design Babies with gestational age below 35 weeks, and with birth weight below 10th centile for gestational age, will be randomly allocated to an "early" or "late" enteral feeding regimen, commencing milk feeds on day 2 and day 6 after birth, respectively. Feeds will be gradually increased over 9-13 days (depending on gestational age using a schedule derived from those used in hospitals in the Eastern and South Western Regions of England, based on surveys of feeding practice. Primary outcome measures are time to establish full enteral feeding and necrotising enterocolitis; secondary outcomes include sepsis and growth. The target sample size is 400 babies. This sample size is large enough to detect a clinically meaningful difference of 3 days in time to establish full enteral feeds between the two feeding policies, with 90% power and a 5% 2-sided significance level. Initial recruitment period was 24 months, subsequently extended to 38 months. Discussion There is limited evidence from randomised controlled trials on which to base decisions regarding feeding policy in high risk preterm infants. This multicentre trial will help to guide clinical practice and may also

  2. Early versus Late Enteral Feeding in Preterm Intrauterine Growth Restricted Neonates with Antenatal Doppler Abnormalities: An Open-Label Randomized Trial.

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    Tewari, Vishal Vishnu; Dubey, Sachin Kumar; Kumar, Reema; Vardhan, Shakti; Sreedhar, C M; Gupta, Girish

    2018-02-01

    Enteral feeding in preterm neonates with intrauterine growth restriction (IUGR) and absent or reversed end diastolic flow (AREDF) on umbilical artery (UA) Doppler is delayed owing to an increased risk of necrotizing enterocolitis (NEC). Delaying enteral feeding with longer duration of parenteral nutrition (PN) carries an increased risk of sepsis. To study early versus late feeding in preterm IUGR neonates for time required to attain sufficient feed volume to discontinue PN and increased risk of NEC or feed intolerance (FI). Open-label randomized controlled trial. Tertiary care neonatal unit and fetal-maternal medicine unit in India. Preterm intrauterine growth restricted neonates' ≤32 weeks with AREDF on UA Doppler enrolled from 1 January 2014 to 31 July 2015. Randomized to receive early or late feeding using mothers own or donor breast milk as per a feed initiation and advancement protocol. Time in days required to attain sufficient feed volume allowing discontinuation of PN and incidence of NEC in neonates fed early versus late. There were 77 eligible neonates. Sixty-two neonates were included and stratified as extreme preterm (27-29 weeks) (n = 20) and very preterm (30-32 weeks) (n = 42). Ten extreme preterm and 21 very preterm neonates were randomized to each early feeding and late feeding arm. There was a significantly faster attainment of sufficient feeds in the early feeding arm of both the stratified groups [extreme preterm: median 14 days (Interquartile range IQR: 12-15) compared with 18 days (IQR: 18-20), hazard ratio (HR): 1.59, 95% CI: 0.626-4.078; very preterm: 12 days (IQR: 10-14) as compared with 16 days (IQR 15-17), HR: 1.89, 95% CI: 1.011-3.555]. There was no difference in the incidence of NEC, FI and combined outcome of NEC and FI. Early feeding in preterm IUGR neonates with AREDF on antenatal UA Doppler allowed earlier discontinuation of PN, allowing birth weight to be regained earlier and did not increase the incidence of NEC and FI.

  3. Abnormal umbilical artery Doppler velocimetry and placental ...

    African Journals Online (AJOL)

    Background. Doppler velocimetry (DV) is widely used to assess the vascular formation of the placenta in fetal growth restriction (FGR) and to estimate the haemodynamic condition of the growth-restricted fetus. Umbilical artery (UA) flow is essentially placental, rather than fetal. Hence, DV provides information about the fetal ...

  4. Longitudinal study of aortic isthmus Doppler in appropriately grown and small-for-gestational-age fetuses with normal and abnormal umbilical artery Doppler.

    LENUS (Irish Health Repository)

    Kennelly, M M

    2012-04-01

    To establish reference ranges using longitudinal data for aortic isthmus (AoI) Doppler indices in appropriate-for-gestational-age (AGA) fetuses and to document the longitudinal trends in a cohort of small-for-gestational-age (SGA) fetuses with normal umbilical artery Doppler and in fetuses with intrauterine growth restriction (IUGR) and abnormal umbilical artery Doppler.

  5. Placental pathology and neonatal outcome in small for gestational age pregnancies with and without abnormal umbilical artery Doppler flow.

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    Ganer Herman, Hadas; Barber, Elad; Gasnier, Rose; Gindes, Liat; Bar, Jacob; Schreiber, Letizia; Kovo, Michal

    2018-01-09

    To compare neonatal outcome and placental pathology in cases of small for gestational age (SGA) according to umbilical artery (UA) Doppler flow. Pregnancy and placental reports of SGA neonates (birth-weight Doppler indices. Placental lesions were classified to malperfusion lesions and inflammatory responses. The abnormal Doppler group (n = 66) delivered at an earlier gestational age, compared to the normal Doppler group (n = 92). Placentas from the abnormal Doppler group were characterized by a higher rate of maternal malperfusion lesions, while placentas from the normal Doppler group exhibited a higher rate of chronic villitis. Neonatal outcome was independently associated with abnormal Doppler, gestational age and birth weight Doppler flow and placental malperfusion, and an inflammatory mechanism, with normal Doppler flow and chronic villitis. Copyright © 2018 Elsevier B.V. All rights reserved.

  6. Umbilical artery doppler abnormalities and associated factors in ...

    African Journals Online (AJOL)

    Background: Umbilical artery (UA) Doppler velocimetry detects foetuses at risk of asphyxia from IUGR before changes in the CTG and biophysical score are evident. This has made it a primary fetal surveillance tool in pre-eclampsia in developed countries with resultant reduction in perinatal mortality by 29%. Iatrogenic ...

  7. Obstetric outcomes in pregnancies with normal nuchal translucency and abnormal ductus venosus Doppler in the first trimester ultrasonography.

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    Seckin, K D; Karslı, M F; Baser, E; Yeral, M I; Tasin, C; Ozgu Erdinc, A S; Danisman, N

    2016-05-01

    In the present case-control study, we evaluated obstetric outcomes of pregnancies with normal nuchal translucency (NT) and abnormal ductus venosus (DV) Doppler findings in the first trimester combined screening test for chromosomal abnormalities. All study patients underwent DV Doppler examination, concurrent with the combined screening test. DV Doppler revealed pathologic findings in 14 pregnant women despite normal NT after the elimination of lost to follow-up and foetal anomaly. Obstetric outcomes of the case patients were compared with a control group that were matched for mean gestational age, and Crown-rump length with normal NT and DV Doppler measurements was selected comprising 88 pregnant women. Regarding maternal outcomes, women with abnormal DV Doppler findings had a higher rate of placental abruption, delivered at an earlier mean gestational age (preterm delivery). Interestingly, a higher rate of spontaneous vaginal delivery rate was observed in these patients. From the foetal perspective, pregnancies with abnormal DV Doppler had lower birth weight and received lower Apgar scores. In conclusion, an abnormal DV Doppler test in the first trimester was associated with poor maternal and foetal obstetric outcomes. These findings should be elucidated in future studies.

  8. Abnormal Doppler flow velocimetry in the growth restricted foetus as a predictor for necrotising enterocolitis.

    Directory of Open Access Journals (Sweden)

    Bhatt A

    2002-07-01

    Full Text Available BACKGROUND: Obstetric decision- making for the growth restricted foetus has to take into consideration the benefits and risks of waiting for pulmonary maturity and continued exposure to hostile intra-uterine environment. Necrotising Enterocolitis (NEC results from continued exposure to hostile environment and is an important cause of poor neonatal outcome. AIMS: To evaluate the predictive value of abnormal Doppler flow velocimetry of the foetal umbilical artery for NEC and neonatal mortality. SETTINGS AND DESIGN: A retrospective study carried out at a tertiary care centre for obstetric and neonatal care. MATERIALS AND METHOD: Seventy-seven neonates with birth weight less than 2000 gm, born over a period of 18 months were studied. These pregnancies were identified as having growth abnormalities of the foetus. Besides other tests of foetal well-being, they were also subjected to Doppler flow velocimetry of the foeto-placental vasculature. Obstetric outcome was evaluated with reference to period of gestation and route of delivery. The neonatal outcome was reviewed with reference to birth weight, Apgar scores and evidence of NEC. STATISTICAL ANALYSIS USED: Chi square test. RESULTS: In the group of patients with Absent or Reverse End Diastolic Frequencies (A/R EDF in the umbilical arteries, positive predictive value for NEC was 52.6%, (RR 30.2; OR 264. The mortality from NEC was 50%. When umbilical artery velocimetry did not show A/REDF, there were no cases of NEC or mortality. Abnormal umbilical or uterine artery flow increased the rate of caesarean section to 62.5% as compared to 17.6% in cases where umbilical artery flow was normal. CONCLUSION: In antenatally identified pregnancies at risk for foetal growth restriction, abnormal Doppler velocimetry in the form of A/REDF in the umbilical arteries is a useful guide to predict NEC and mortality in the early neonatal period.

  9. Abnormal uterine bleeding due to vascular abnormality caused by D and E : doppler sonography for diagnosis and transcatheter arterial embolization for treatment

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    Kim, Yong Jo; Heo, Chan; Jung, Tae Gun; Kim, Gi Sung; Kwon, Hyeok Po; Lee, Sang Kwon; Kwon, Jung Hyeok [Dongkang Hospital, Ulsan (Korea, Republic of); Lee, Yeong Hwan [Taegu Catholic Univ. School of Medicine, Taegu (Korea, Republic of)

    1996-06-01

    We attempted to evaluate the usefulness of Doppler sonography in the diagnosis of uterine vascular abnormality caused by previous D and E, and to report that transarterial embolization is an excellent treatment modality. We analyzed gray-scale US, color/duplex Doppler US and angiographic findings in seven patients with radiologically proven uterine vascular abnormality. Two of the seven cases were pseudoaneurysms and five of the seven cases were AVMs. n one of the AVMS, two small pseudoaneurysms were combined. In all cases, transarterial embolizations using 3 mm coil or/and gelfoam particles were performed. Follow-up US studies, including color Doppler US, were performed. on color/duplex Doppler sonography, two cases of pseudoaneurysm showed blood pools with turbulent arterial flow, and five cases of AVM showed asymmetrically increased cascularity, with vailable high velocities composed of the pulsatile arterial flow, with a high diastolic component. on angiography, the former showed pseudoaneruysmal sacs, and the latter densely opacified vascular tangles. No more abnormal uterine bleeding was shown following transarterial embolization in all cases. Color/duplex Doppler sonography was valuable in the diagnosis or treatment of abnormal uterine bleeding caused by uterine vascular abnormality such as acquired AVM or pseudoaneruysm.

  10. Association between maternal vascular murmur and the small-for-gestational-age fetus with abnormal umbilical artery Doppler flow

    DEFF Research Database (Denmark)

    Riknagel, Diana; Farlie, Richard; Hedegaard, Morten

    2017-01-01

    OBJECTIVE: To investigate the association between maternal vascular murmurs (MVMs) and fetal growth restriction (defined as small-for-gestational-age [SGA] fetus) and abnormal Doppler pulsatility index (PI) of the uterine and/or umbilical arteries. METHODS: A cross-sectional study of women aged 18...... participants had MVMs. There was a clear association between MVMs and a composite of SGA and an abnormal PI of the uterine and/or the umbilical artery (PMaternal vascular murmurs are significantly associated with fetal growth restriction...

  11. Use of Systemic Vasodilators for the Management of Doppler Ultrasound Arterial Abnormalities After Orthotopic Liver Transplantation.

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    Mohkam, Kayvan; Fanget, Florian; Darnis, Benjamin; Harbaoui, Brahim; Rode, Agnès; Charpiat, Bruno; Ducerf, Christian; Mabrut, Jean-Yves

    2016-12-01

    Doppler ultrasound (DUS) arterial abnormalities (DAA) after orthotopic liver transplantation (OLT) often represent a sign of hepatic artery (HA) complication (HAC). The standard management of DAA involves computed tomographic angiography (CTA) followed by invasive vascular intervention (IVI) or observation. We evaluated the contribution of systemic vasodilators (SVD) to the management of DAA after OLT. Between 2005 and 2015, 91 of 514 OLT recipients developed DAA (defined by HA resistive index [HARI] ultrasound was performed 2 days later, and patients were assigned to 3 groups accordingly: the normalization group (HARI >0.5), improvement group (HARI increase of >0.1 but value <0.5), or nonresponse group. We analyzed the contribution of this strategy to predict clinically significant HAC, defined as thrombosis or HAC requiring IVI. A clinically significant HAC (4 thromboses, 35 HACs requiring IVI) was found in 2.9% (n = 1/34), 32.1% (n = 9/28), and 100% (n = 29/29) of patients in the normalization, improvement, and nonresponse groups, respectively (P < 0.001). On multivariate analysis, absence of HARI normalization after SVD and time to DAA longer than 30 days were associated with clinically significant HAC. Specificity and accuracy of DUS after SVD increased from 88.1% to 95.1% and from 88.9% to 95.1% (P < 0.001), without altering its sensitivity (97.7% vs 95.5%, P = 1.000). The use of SVD improves the diagnostic performance of DUS for clinically significant HAC after OLT. It allows identifying patients at low risk for HAC, for whom CTA could be avoided, and helps choosing between observation and IVI in patients with inconclusive CTA.

  12. Mid-gestation brain Doppler and head biometry in fetuses with congenital heart disease predict abnormal brain development at birth.

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    Masoller, N; Sanz-CortéS, M; Crispi, F; Gómez, O; Bennasar, M; Egaña-Ugrinovic, G; Bargalló, N; Martínez, J M; Gratacós, E

    2016-01-01

    Fetuses with congenital heart disease (CHD) show evidence of abnormal brain development before birth, which is thought to contribute to adverse neurodevelopment during childhood. Our aim was to evaluate whether brain development in late pregnancy can be predicted by fetal brain Doppler, head biometry and the clinical form of CHD at the time of diagnosis. This was a prospective cohort study including 58 fetuses with CHD, diagnosed at 20-24 weeks' gestation, and 58 normal control fetuses. At the time of diagnosis, we recorded fetal head circumference (HC), biparietal diameter, middle cerebral artery pulsatility index (MCA-PI), cerebroplacental ratio (CPR) and brain perfusion by fractional moving blood volume. We classified cases into one of two clinical types defined by the expected levels (high or low) of placental (well-oxygenated) blood perfusion, according to the anatomical defect. All fetuses underwent subsequent 3T-magnetic resonance imaging (MRI) at 36-38 weeks' gestation. Abnormal prenatal brain development was defined by a composite score including any of the following findings on MRI: total brain volume type of CHD was not. Fetal brain Doppler and head biometry at the time of CHD diagnosis are independent predictors of abnormal brain development at birth, and could be used in future algorithms to improve counseling and targeted interventions. Copyright © 2015 ISUOG. Published by John Wiley & Sons Ltd. Copyright © 2015 ISUOG. Published by John Wiley & Sons Ltd.

  13. The pro-BNP Serum Level and Echocardiographic Tissue Doppler Abnormalities in Patients with Beta Thalassemia Major.

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    Garadah, Taysir S; Mahdi, Najat; Kassab, Salah; Shoroqi, Isa Al; Abu-Taleb, Ahmed; Jamsheer, Anwer

    2010-12-20

    Doppler echocardiographic studies of the left ventricle (LV) function in patients with β-Thalassemia Major (β-TM) had shown different patterns of systolic and diastolic dysfunctions associated with abnormal serum brain natriuretic peptide (BNP). This cross-sectional study was designed to study the LV systolic and diastolic functions and correlate that with serum level of N-terminal pro brain natriuretic hormone (NT- pro BNP) in patients with β-TM using Pulsed Doppler (PD) and Tissue Doppler (TD) echocardiography. The study was conducted on patients with β-TM (n = 38, age 15.7 ± 8.9 years) and compared with an age-matched controls (n = 38, age 15.9 ± 8.9 years). In all participants, PD and TD echocardiography were performed and blood samples were withdrawn for measuring the serum level of NT-pro BNP, ferritin, and alanine transaminase. Patients with β-TM compared with controls, have thicker LV septal wall index (0.65 ± 0.26 vs. 0.44 ± 0.21 cm, P pro-BNP in β-TM was significantly higher compared with controls (37.6 ± 14.73 vs. 5.5 ± 5.4pg/ml, P pro BNP that is positively correlated with the E/Em ratio on tissue Doppler. Furthermore, we confirm our previous findings that patients with β-TM exhibit LV diastolic pattern on echocardiogram suggestive of restrictive type with well preserved left ventricle systolic function.

  14. The effect of low-dose aspirin on fetal weight of idiopathic asymmetrically intrauterine growth restricted fetuses with abnormal umbilical artery Doppler indices: a randomized clinical trial.

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    Ali, Mohammed K; Abbas, Ahmed M; Yosef, Ali H; Bahloul, Mustafa

    2017-07-11

    To investigate the effect of aspirin on fetal weight in fetuses with idiopathic asymmetrical intrauterine growth restriction (IUGR) complicated by abnormal umbilical artery Doppler indices. The study was a randomized controlled trial conducted at Woman's Health Hospital, Assiut, Egypt, between June 2016 and the January 2017 included 60 pregnant women (28-30 weeks) with idiopathic asymmetrical IUGR associated with abnormal umbilical artery Doppler indices. Women were randomly assigned to group I (aspirin 75 mg) daily for four weeks or group II (no intervention). The primary outcome was the fetal weight after four weeks. Secondary outcomes included Doppler blood flow changes in the umbilical artery plus delivery and neonatal outcomes. The estimated fetal weight and umbilical artery blood flow increased significantly in aspirin group (p = .00) when compared with no intervention group. As regard neonatal outcomes; aspirin group showed better results and encouraging outcomes (p Doppler blood flow.

  15. Perinatal outcome and placental apoptosis in patients with late-onset pre-eclampsia and abnormal uterine artery Doppler at diagnosis.

    Science.gov (United States)

    Rodríguez, Marcelo; Couve-Pérez, Constanza; San Martín, Sebastián; Martínez, Felipe; Lozano, Carlo; Sepúlveda-Martínez, Alvaro

    2017-04-28

    To determine the rate of placental apoptosis and adverse perinatal outcome in patients with late pre-eclampsia and altered uterine artery (UtA) Doppler. A cohort study was performed. Patients with a diagnosis of late pre-eclampsia (l-PE) were stratified according to the UtA Doppler status at diagnosis (below or above the 95 th percentile). A logistic regression analysis was performed to identify the association between an abnormal UtA Doppler and the presence of adverse maternal and perinatal outcomes. In a subset of this cohort, an immunohistochemical analysis of the placenta was performed to identify the rate of apoptosis and the association with the UtA Doppler against normotensive controls. A non-parametric linear trend analysis was performed for the assessment of the apoptosis index. Eighty-six patients were included in the final analysis. The UtA Doppler was above the 95 th percentile in 33 (38.4%) patients. Interestingly, the gestational age at diagnosis and delivery were significantly lower in this group compared to the patients with a normal UtA Doppler. An abnormal UtA Doppler was associated with an increased risk of severe PE (OR= 7.5; 95% CI 2.76 - 20.46; p Doppler assessment (p = 0.04). In patients with l-PE, the UtA Doppler was useful not only for the clinical classification but also for the placental histological findings. The correlation between the UtA Doppler and the apoptosis index provides new evidence of a sub-group of l-PE patients with a placental origin of the disease. This article is protected by copyright. All rights reserved.

  16. Associations between abnormal ultrasound color Doppler measures and tendon pain symptoms in badminton players during a season

    DEFF Research Database (Denmark)

    Boesen, Anders Ploug; Boesen, Morten Ilum; Torp-Pedersen, Soren

    2012-01-01

    Color Doppler ultrasound is widely used to examine intratendinous flow in individuals with overuse tendon problems, but the association between color Doppler and pain is still unclear.......Color Doppler ultrasound is widely used to examine intratendinous flow in individuals with overuse tendon problems, but the association between color Doppler and pain is still unclear....

  17. Maternal venous Doppler characteristics are abnormal in pre-eclampsia but not in gestational hypertension.

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    Gyselaers, W; Staelens, A; Mesens, T; Tomsin, K; Oben, J; Vonck, S; Verresen, L; Molenberghs, G

    2015-04-01

    To compare functional characteristics of maternal thoraco-abdominal arteries and veins in proteinuric and non-proteinuric hypertension in pregnancy. This retrospective study included women with singleton pregnancies during the third trimester, which were either uncomplicated or complicated with different clinical types of hypertension: non-proteinuric gestational hypertension (GH), early-onset pre-eclampsia (PE) diagnosed 150 pregnancies were evaluated: 22 with uncomplicated pregnancy, 41 GH, 31 early PE and 56 late PE. Aortic VI and ACI were lower in GH, early PE and late PE than in uncomplicated pregnancy. Both early PE and late PE differed from GH by having shorter APTT in the uterine arcuate arteries and higher RIVI. Hemodynamic abnormalities were most pronounced in early PE, during which uterine arcuate artery RI was higher and VPTT in kidneys was shorter than in late PE. There was a significant correlation between degree of proteinuria and RIVI for the left (r = 0.381) and right (r = 0.347) kidney in late PE, but this was not true for early PE. There is a gradient of worsening arterial and venous hemodynamic abnormalities from GH to late PE and then to early PE. Venous hemodynamic abnormalities are present only in PE, with a linear correlation between proteinuria and RIVI in late PE. The role of the maternal venous compartment in the pathophysiology and etiology of PE-related symptoms may be much more important than considered at present. Copyright © 2014 ISUOG. Published by John Wiley & Sons Ltd.

  18. Early Reticulocytosis and Anemia Are Associated with Abnormal and Conditional Transcranial Doppler Velocities in Children with Sickle Cell Anemia.

    Science.gov (United States)

    Meier, Emily Riehm; Fasano, Ross M; Estrada, Monica; He, Jianping; Luban, Naomi L C; McCarter, Robert

    2016-02-01

    To improve prediction of sickle cell anemia severity at an early age, we evaluated whether absolute reticulocyte count (ARC) or hemoglobin (Hb) levels during early infancy (2-6 months of age) in patients with sickle cell anemia predict the risk of later developing an abnormal (abTCD) or conditional (cdTCD) Transcranial Doppler (TCD). We used chart review to identify 121 consecutive patients who underwent TCD screening and had steady state ARC and Hb levels recorded between 2 and 6 months of age. Cox regression analysis was used to determine the relationship between ARC, Hb levels, and risk of developing cdTCD/abTCD over time. Mean ARC in early infancy was highest and mean Hb lowest in those children with abTCDs and cdTCDs. Cox regression analysis revealed that those subjects with an ARC ≥200 K/μL in early infancy had nearly 3 times the risk of having an abTCD/cdTCD than the group with an ARC <200 K/μL, and patients with a Hb <8.5 g/dL had 2.7 times the risk of having an abTCD/cdTCD. These data suggest that both elevated ARC and low baseline Hb during early infancy are associated with an increased risk of developing a cdTCD or abTCD later in childhood. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. Evaluation of splanchnic oximetry, Doppler flow velocimetry in the superior mesenteric artery and feeding tolerance in very low birth weight IUGR and non-IUGR infants receiving bolus versus continuous enteral nutrition

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    Bozzetti Valentina

    2012-07-01

    Full Text Available Abstract Background IUGR infants are thought to have impaired gut function after birth, which may result in intestinal disturbances, ranging from temporary intolerance to the enteral feeding to full-blown NEC. In literature there is no consensus regarding the impact of enteral feeding on intestinal blood flow and hence regarding the best regimen and the best rate of delivering the enteral nutrition. Methods/design This is a randomized, non-pharmacological, single-center, cross-over study including 20 VLBW infants. Inclusion criteria * Weight at birth ranging: 700–1501 grams * Gestational age up to 25 weeks and 6 days * Written informed consent from parents or guardians Exclusion criteria * Major congenital abnormality * Patients enrolled in other trials * Significant multi-organ failure prior to trial entry * Pre-existing cutaneous disease not allowing the placement of the NIRS’ probe In the first 24 hours of life, between the 48th and 72nd hours of life, and during Minimal Enteral Feeding, all infants’ intestinal perfusion will be evaluated with NIRS and a Doppler of the superior mesenteric artery will be executed. At the achievement of an enteral intake of 100 mL/Kg/day the patients (IUGR and NON IUGR separately will be randomized in 2 groups: Group A (n=10 will receive a feed by bolus (in 10 minutes; then, after at least 3 hours, they will receive the same amount of formula administered in 3 hours. Group B (n=10 will receive a feed administered in 3 hours followed by a bolus administration of the same amount of formula (in 10 minutes after at least 3 hours. On the randomization day intestinal and cerebral regional oximetry will be measured via NIRS. Intestinal and celebral oximetry will be measured before the feed and 30 minutes after the feed by bolus during the 3 hours nutrition the measurements will be performed before the feed, 30 minutes from the start of the nutrition and 30 minutes after the end of the gavage. An evaluation

  20. Associations between abnormal ultrasound color Doppler measures and tendon pain symptoms in badminton players during a season: a prospective cohort study.

    Science.gov (United States)

    Boesen, Anders Ploug; Boesen, Morten Ilum; Torp-Pedersen, Soren; Christensen, Robin; Boesen, Lars; Hölmich, Per; Nielsen, Michael Bachmann; Koenig, Merete Juhl; Hartkopp, Andreas; Ellegaard, Karen; Bliddal, Henning; Langberg, Henning

    2012-03-01

    Color Doppler ultrasound is widely used to examine intratendinous flow in individuals with overuse tendon problems, but the association between color Doppler and pain is still unclear. Intratendinous flow is present and associated with pain in badminton players, and intratendinous flow and pain increase during a badminton season. Cohort study (prognosis); Level of evidence, 2. Ninety-five semiprofessional badminton players were included in the study at a tournament at the start of the badminton season. All players were interviewed regarding pain. The anterior knee tendons and Achilles tendons were studied. Each tendon was scored using a quantitative grading system (grades 0-5) and a qualitative scoring system (color fraction) using color Doppler ultrasound. Eight months later, 86 of the players (91%) were retested by the same investigators during an equivalent badminton tournament (including 1032 tendon regions; 86 players with 4 tendons each with 3 regions), thus forming the study group. At the start of the season, 24 players (28%) experienced pain in 37 tendons (11%), and at the end of the season, 31 players (36%) experienced pain in 51 tendons (15%), which was a statistically significant increase (P = .0002). Abnormal flow was found in 230 tendon regions in 71 players (83%) at the start of the season compared with 78 tendon regions in 41 players (48%) at the follow-up. The decrease in abnormal flow was statistically significant (P < .0001). Of the 37 painful tendons at the start of the season, 25 had abnormal flow (68%). In contrast, 131 tendons (85%) with abnormal flow at the start of the season were pain free. At the end of the season, 18 of the 51 painful tendons (35%) had abnormal flow. Ninety-six of the 131 pain-free tendons (73%) with abnormal flow at the start of the season were normalized (no pain and normal flow) at the end of the season. It was not possible to verify any association between intratendinous flow and pain at the start of the season or at

  1. Abnormal uterine artery Doppler in pregnancies suspected of a SGA fetus is related to increased risk of recurrence during next pregnancy.

    Science.gov (United States)

    Saemundsson, Ymir; Svantesson, Henrik; Gudmundsson, Saemundur

    2009-01-01

    To investigate if placental Doppler velocimetry can predict the recurrence of a small-for-gestational age (SGA) fetus in subsequent pregnancies. Retrospective study. City cohort over 15 years attending a university hospital. A total of 196 pregnancies suspected of a SGA fetus (SGA newborn during the succeeding pregnancy by Doppler results from the previous pregnancy. In the group of 196 pregnancies suspected for SGA, 27 (13.8%) delivered a SGA newborn in the following pregnancy. Thirty-seven (18.9%) of the 196 had an abnormally high PI in the uterine arteries in their first pregnancy, 12 (32.4%) of these delivered a SGA child in the next pregnancy (relative risk 3.44, pSGA (p=0.051). Uterine artery notching was not related to a SGA newborn during next pregnancy. The results suggest that abnormal uterine artery Doppler is related to increased risk of recurrence of SGA during the next pregnancy. This knowledge might provide the clinician with an opportunity to initiate preventive treatment and increase surveillance to women at risk during succeeding pregnancy.

  2. Association of maternal and umbilical cord blood leptin concentrations and abnormal color Doppler indices of umbilical artery with fetal growth restriction

    Directory of Open Access Journals (Sweden)

    Elahe Zareaan

    2017-08-01

    Full Text Available Background: Fetal growth restriction (FGR is a condition with heterogeneous pathophysiology which characterized by fetal weight less than the tenth percentile for gestational age. Several factors have impact on maternal, placental and fetal due to growth restriction. Objective: The aim of this study was to investigate the relationship between levels of leptin in the cord, and serum leptin of mothers also abnormal color Doppler indices of umbilical artery with fetal growth restriction. Materials and Methods: This is a cross sectional study conducted in Isfahan, Iran, 2015-2016. We recruited 40 women with singleton pregnancies complicated by fetal growth restriction (Group I and 40 pregnant women with normal fetal growth (Group II with matched age. Maternal serum and umbilical artery leptin levels were determined with Enzyme-Linked immunosorben method. Also, color Doppler ultrasound of umbilical artery was performed. Results: Mean maternal and fetal leptin levels were lower in the FGR group compared to the normal group (36.58±(20.99 and 7.42 ±(4.08vs. 47.32±(22.50 and 30.49±(14.50 respectively. Also, mean fetal leptin level was lower in the group with abnormal color Doppler sonographic indices compared to the normal group (7. 40 ±(4.10vs 27.06±(15.80, respectively. Conclusion: This study indicated that maternal and fetal leptin levels are correlated with FGR originating from damaged placental function; also fetal leptin level can indicate changes in color Doppler sonographic indices.

  3. Impact of aspirin on trophoblastic invasion in women with abnormal uterine artery Doppler at 11-14 weeks: a randomized controlled study.

    Science.gov (United States)

    Scazzocchio, E; Oros, D; Diaz, D; Ramirez, J C; Ricart, M; Meler, E; González de Agüero, R; Gratacos, E; Figueras, F

    2017-04-01

    Defective trophoblastic invasion is a key feature in many cases of pre-eclampsia (PE). Uterine artery (UtA) Doppler is a validated non-invasive proxy for trophoblastic invasion. The aim of this study was to explore whether low-dose aspirin, administered from the first trimester, improves trophoblastic invasion, evaluated by UtA Doppler during the second and third trimesters in women defined as high risk by abnormal first-trimester UtA Doppler. This randomized Phase-II study had a triple-blind, parallel-arm, controlled design. Singleton pregnancies with abnormal mean UtA Doppler at 11-14 weeks and absence of other major risk factors for PE received 150 mg extended-release aspirin or identical-appearing placebo tablets from study inclusion to 28 weeks. Main outcome measure was UtA pulsatility index (PI) at 28 weeks' gestation. Secondary outcomes included frequency of development of PE and growth restriction/small-for-gestational age (SGA). A total of 155 women completed the follow-up and were analyzed. No difference in mean UtA-PI was found between women in the aspirin and placebo groups at 28 weeks (mean UtA-PI Z-score (mean ± SD), 0.99 ± 1.48 vs 0.85 ± 1.25; P = 0.52). Seven women developed PE: four (5%) in the aspirin group and three (4%) in the placebo group. There was a trend toward lower incidence of SGA in the aspirin group (8.8% vs 17.3%; P = 0.11). In women with defective trophoblastic invasion, as reflected by abnormal UtA Doppler, low-dose aspirin started in the first trimester does not have a significant effect on UtA impedance as pregnancy progresses; however, the study was underpowered to detect potential small effects . Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd.

  4. The maternal plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated in SGA and the magnitude of the increase relates to Doppler abnormalities in the maternal and fetal circulation.

    Science.gov (United States)

    Chaiworapongsa, Tinnakorn; Espinoza, Jimmy; Gotsch, Francesca; Kim, Yeon Mee; Kim, Gi Jin; Goncalves, Luis F; Edwin, Samuel; Kusanovic, Juan Pedro; Erez, Offer; Than, Nandor Gabor; Hassan, Sonia S; Romero, Roberto

    2008-01-01

    The soluble form of vascular endothelial growth factor receptor-1 (sVEGFR-1), an antagonist to vascular endothelial growth factor and placental growth factor, has been implicated in the pathophysiology of preeclampsia. Preeclampsia and pregnancy complicated with small for gestational age (SGA) fetuses share some pathophysiologic derangements, such as failure of physiologic transformation of the spiral arteries, endothelial cell dysfunction, and leukocyte activation. The objectives of this study were to: (1) determine whether plasma concentrations of sVEGFR-1 in mothers with SGA fetuses without preeclampsia at the time of diagnosis are different from those in patients with preeclampsia or normal pregnant women, and (2) examine the relationship between plasma concentrations of sVEGFR-1 and Doppler velocimetry in uterine and umbilical arteries in patients with preeclampsia and those with SGA. A cross-sectional study was conducted to determine the concentrations of the soluble form of VEGFR-1 in plasma obtained from normal pregnant women (n = 135), women with SGA fetuses (n = 53), and patients with preeclampsia (n = 112). Patients with SGA fetuses and those with preeclampsia were sub-classified according to the results of uterine and umbilical artery Doppler velocimetry examinations. Plasma concentrations of sVEGFR-1 were determined by an ELISA. Since these concentrations change with gestational age, differences among various subgroups were statistically estimated with the delta value, defined as the difference between the observed and expected plasma sVEGFR-1 concentration. The expected values were derived from regression analysis of plasma sVEGFR-1 concentrations in normal pregnancy. Regression analysis and univariate and multivariate analysis were employed. (1) Mothers with SGA fetuses had a mean plasma concentration of sVEGFR-1 higher than normal pregnant women (p SGA fetuses, only those with abnormal uterine artery Doppler velocimetry had a mean plasma sVEGFR-1

  5. An evaluation of the use of new Doppler methods for detecting longitudinal function abnormalities in a pacing-induced heart failure model

    Science.gov (United States)

    Tabata, Tomotsugu; Cardon, Lisa A.; Armstrong, Guy P.; Fukamach, Kiyotaka; Takagaki, Masami; Ochiai, Yoshie; McCarthy, Patrick M.; Thomas, James D.

    2003-01-01

    BACKGROUND: Doppler tissue echocardiography and color M-mode Doppler flow propagation velocity have proven useful in evaluating cross-sections of patients with left ventricular (LV) dysfunction, but experience with serial changes is limited. Purpose and methods: We tested their use by evaluating the temporal changes of LV function in a pacing-induced congestive heart failure model. Rapid ventricular pacing was initiated and maintained in 20 dogs for 4 weeks. Echocardiography was performed at baseline and weekly during brief pacing cessation. RESULTS: With rapid pacing, LV volume significantly increased and ejection fraction (57%-28%), stroke volume (37-18 mL), and mitral annulus systolic velocity (16.1-6.6 cm/s) by Doppler tissue echocardiography significantly decreased, with ejection fraction and mitral annulus systolic velocity closely correlated (r = 0.706, P function, respectively. CONCLUSIONS: Doppler tissue echocardiography and color M-mode Doppler flow could evaluate the serial deterioration in LV dysfunction throughout the pacing period. These were more useful in quantifying progressive LV dysfunction than conventional ehocardiographic techniques, and were probably relatively independent of preload. These techniques could be suitable for longitudinal evaluation in addition to the cross-sectional study.

  6. Postoperative doppler evaluation of liver transplants

    Directory of Open Access Journals (Sweden)

    Rupan Sanyal

    2014-01-01

    Full Text Available Doppler ultrasound plays an important role in the postoperative management of hepatic transplantation, by enabling early detection and treatment of various vascular complications. This article describes the normal Doppler findings following liver transplantation and reviews the imaging appearances of various vascular complications associated with it. The article also discusses transient waveform abnormalities, often seen on a post-transplant Doppler examination, and the importance of differentiating them from findings suggestive of ominous vascular complications.

  7. Postoperative doppler evaluation of liver transplants

    Science.gov (United States)

    Sanyal, Rupan; Zarzour, Jessica G; Ganeshan, Dakshina M; Bhargava, Puneet; Lall, Chandana G; Little, Mark D

    2014-01-01

    Doppler ultrasound plays an important role in the postoperative management of hepatic transplantation, by enabling early detection and treatment of various vascular complications. This article describes the normal Doppler findings following liver transplantation and reviews the imaging appearances of various vascular complications associated with it. The article also discusses transient waveform abnormalities, often seen on a post-transplant Doppler examination, and the importance of differentiating them from findings suggestive of ominous vascular complications. PMID:25489129

  8. Abnormal umbilical artery Doppler velocimetry and placental ...

    African Journals Online (AJOL)

    stromal fibrosis and calcification). The placental lesions were then compared with DV findings (at delivery) and prospectively with neonatal outcome. Statistical analysis. Statistical software SPSS version 20.0 (IBM Corp., USA) was used for statistical ...

  9. Radiation enteritis

    Science.gov (United States)

    Radiation enteropathy; Radiation-induced small bowel injury; Post-radiation enteritis ... Radiation therapy uses high-powered x-rays, particles, or radioactive seeds to kill cancer cells. The therapy ...

  10. The doppler ultrasound. La ecografia Doppler

    Energy Technology Data Exchange (ETDEWEB)

    Contreras Cecilia, E.; Lozano Setien, E.; Hernandez Montero, J.; Ganado Diaz, T.; Jorquera Moya, M.; Blasco Pascual, E. (Hospital Universitario San Carlos. Madrid (Spain))

    1994-01-01

    The discovery and development of Doppler ultrasound has had a great influence on Medical practice since it allows the noninvasive study of vascular pathology, both arterial and venous, as well as the flow patterns of the different parenchyma. This article deals with the principles, limitations and interpretation of the Doppler signal, as well as the different Doppler ultrasound systems routinely employed in Medicine.

  11. Doppler tracking

    Science.gov (United States)

    Thomas, Christopher Jacob

    This study addresses the development of a methodology using the Doppler Effect for high-resolution, short-range tracking of small projectiles and vehicles. Minimal impact on the design of the moving object is achieved by incorporating only a transmitter in it and using ground stations for all other components. This is particularly useful for tracking objects such as sports balls that have configurations and materials that are not conducive to housing onboard instrumentation. The methodology developed here uses four or more receivers to monitor a constant frequency signal emitted by the object. Efficient and accurate schemes for filtering the raw signals, determining the instantaneous frequencies, time synching the frequencies from each receiver, smoothing the synced frequencies, determining the relative velocity and radius of the object and solving the nonlinear system of equations for object position in three dimensions as a function of time are developed and described here.

  12. Doppler micro sense and avoid radar

    Science.gov (United States)

    Gorwara, Ashok; Molchanov, Pavlo; Asmolova, Olga

    2015-10-01

    There is a need for small Sense and Avoid (SAA) systems for small and micro Unmanned Aerial Systems (UAS) to avoid collisions with obstacles and other aircraft. The proposed SAA systems will give drones the ability to "see" close up and give them the agility to maneuver through tight areas. Doppler radar is proposed for use in this sense and avoid system because in contrast to optical or infrared (IR) systems Doppler can work in more harsh conditions such as at dusk, and in rain and snow. And in contrast to ultrasound based systems, Doppler can better sense small sized obstacles such as wires and it can provide a sensing range from a few inches to several miles. An SAA systems comprised of Doppler radar modules and an array of directional antennas that are distributed around the perimeter of the drone can cover the entire sky. These modules are designed so that they can provide the direction to the obstacle and simultaneously generate an alarm signal if the obstacle enters within the SAA system's adjustable "Protection Border". The alarm signal alerts the drone's autopilot to automatically initiate an avoidance maneuver. A series of Doppler radar modules with different ranges, angles of view and transmitting power have been designed for drones of different sizes and applications. The proposed Doppler radar micro SAA system has simple circuitry, works from a 5 volt source and has low power consumption. It is light weight, inexpensive and it can be used for a variety of small unmanned aircraft.

  13. Advances in Doppler OCT

    Science.gov (United States)

    Liu, Gangjun; Chen, Zhongping

    2014-01-01

    We review the principle and some recent applications of Doppler optical coherence tomography (OCT). The advances of the phase-resolved Doppler OCT method are described. Functional OCT algorithms which are based on an extension of the phase-resolved scheme are also introduced. Recent applications of Doppler OCT for quantification of flow, imaging of microvasculature and vocal fold vibration, and optical coherence elastography are briefly discussed. PMID:24443649

  14. Doppler flowmetry in preeclampsia.

    Science.gov (United States)

    Zahumensky, J

    2009-01-01

    The purpose of this study was to summarize the new published data on the Doppler flowmetry in preeclampsia. We summarize the new published data on the Doppler flowmetry in uteroplacental, fetoplacental and fetal circulation in preeclampsia. The present review summarized the results of clinical research on the Doppler flowmetry in the screening of risk of preclampsia, in the diagnosis of preclampsia and in the fetal risk in preclampsia (Ref. 19). Full Text (Free, PDF) www.bmj.sk.

  15. Syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis (HaNDL) in a patient with confusional symptoms, diffuse EEG abnormalities, and bilateral vasospasm in transcranial Doppler ultrasound: A case report and literature review.

    Science.gov (United States)

    Hidalgo de la Cruz, M; Domínguez Rubio, R; Luque Buzo, E; Díaz Otero, F; Vázquez Alén, P; Orcajo Rincón, J; Prieto Montalvo, J; Contreras Chicote, A; Grandas Pérez, F

    2017-04-17

    HaNDL syndrome (transient headache and neurological deficits with cerebrospinal fluid lymphocytosis) is characterised by one or more episodes of headache and transient neurological deficits associated with cerebrospinal fluid lymphocytosis. To date, few cases of HaNDL manifesting with confusional symptoms have been described. Likewise, very few patients with HaNDL and confusional symptoms have been evaluated with transcranial Doppler ultrasound (TCD). TCD data from patients with focal involvement reveal changes consistent with vasomotor alterations. We present the case of a 42-year-old man who experienced headache and confusional symptoms and displayed pleocytosis, diffuse slow activity on EEG, increased blood flow velocity in both middle cerebral arteries on TCD, and single-photon emission computed tomography (SPECT) findings suggestive of diffuse involvement, especially in the left hemisphere. To our knowledge, this is the first description of a patient with HaNDL, confusional symptoms, diffuse slow activity on EEG, and increased blood flow velocity in TCD. Our findings suggest a relationship between cerebral vasomotor changes and the pathophysiology of HaNDL. TCD may be a useful tool for early diagnosis of HaNDL. Copyright © 2017 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.

  16. Tendinopathy and Doppler activity

    DEFF Research Database (Denmark)

    Boesen, M I; Koenig, M J; Torp-Pedersen, S

    2006-01-01

    Intratendinous Doppler activity has been interpreted as an equivalent of neovessels in the Achilles tendon and as a sign of tendinosis (AT).......Intratendinous Doppler activity has been interpreted as an equivalent of neovessels in the Achilles tendon and as a sign of tendinosis (AT)....

  17. The Doppler Effect

    OpenAIRE

    Riedel, Adric

    2014-01-01

    This presentation of 7 animations demonstrates the Doppler effect, which is used by astronomers to learn about the motions of stars, and to find planets.  The principle is simple - in fact, even the animations consist only of expanding circles - but the effect is impressive.   http://starguyspeaks.wordpress.com/2014/10/12/on-the-doppler-effect/

  18. Ultrasonic colour Doppler imaging

    DEFF Research Database (Denmark)

    Evans, David H.; Jensen, Jørgen Arendt; Nielsen, Michael Bachmann

    2011-01-01

    Ultrasonic colour Doppler is an imaging technique that combines anatomical information derived using ultrasonic pulse-echo techniques with velocity information derived using ultrasonic Doppler techniques to generate colour-coded maps of tissue velocity superimposed on grey-scale images of tissue...... anatomy. The most common use of the technique is to image the movement of blood through the heart, arteries and veins, but it may also be used to image the motion of solid tissues such as the heart walls. Colour Doppler imaging is now provided on almost all commercial ultrasound machines, and has been...... vectors. This review briefly introduces the principles behind colour Doppler imaging and describes some clinical applications. It then describes the basic components of conventional colour Doppler systems and the methods used to derive velocity information from the ultrasound signal. Next, a number of new...

  19. Differential doppler heterodyning technique

    DEFF Research Database (Denmark)

    Lading, Lars

    1971-01-01

    Measuring velocity without disturbing the moving object is possible by use of the laser doppler heterodyning technique. Theoretical considerations on the doppler shift show that the antenna property of the photodetector can solve an apparent conflict between two different ways of calculating...... the detected doppler frequency. It is found that the doppler frequency for this particular setup is independent of the direction of detection. Investigations of the signal-to-noise ratio (SNR) show that the maximum SNR-considering the optical setup-is obtained by measuring the frequency difference between two...... doppler-shifted beams rather than by measuring the shift of a single beam by comparing it with a reference beam. Measurements seem to be in agreement with the theoretical consideration...

  20. The use of fetal Doppler in obstetrics.

    Science.gov (United States)

    Gagnon, Robert; Van den Hof, Michiel

    2003-07-01

    To develop national guidelines on the use of fetal Doppler in obstetrics. Whether umbilical cord artery, umbilical cord venous, ductus venosus, and middle cerebral artery Doppler are useful in assessing fetal health. Prediction of adverse perinatal outcome or prediction of fetal anemia. MEDLINE search and review of bibliographies in identified articles. The evidence was reviewed by the Diagnostic Imaging Committee and the principal authors. A quality of evidence assessment was undertaken as outlined in the report of the Canadian Task Force on the Periodic Health Examination. Intrauterine growth restriction complicates 5% to 10% of all pregnancies and up to 30% of multiple pregnancies. In 60% of these pregnancies, the primary cause is placental insufficiency. Improvement in the identification of the fetus at risk of intrauterine demise may lead to more successful management strategies. Management of fetal red blood cell isoimmunization requires a prediction of fetal anemia. If invasive procedures to predict fetal anemia can be replaced with noninvasive tests, fetal morbidity and mortality can be reduced. 1. Umbilical artery Doppler should be available for assessment of the fetal-placental circulation in pregnant women with suspected severe placental insufficiency. (I-A) 2. Depending on other clinical factors, reduced, absent, or reversed umbilical artery end-diastolic flow is an indication for enhanced fetal surveillance or delivery. If delivery is delayed to enhance fetal lung maturity with maternal administration of glucocorticoid, intensive fetal surveillance until delivery is suggested for those fetuses with reversed end-diastolic flow. (II-1B) 3. Umbilical artery Doppler should not be used as a screening tool in healthy pregnancies, as it has not been shown to be of value in this group. (I-A) 4. Umbilical venous double pulsations, in the presence of abnormal umbilical artery Doppler waveforms, necessitate a detailed assessment of fetal health status. (II-3B) 5

  1. Automatic extraction of disease-specific features from Doppler images

    Science.gov (United States)

    Negahdar, Mohammadreza; Moradi, Mehdi; Parajuli, Nripesh; Syeda-Mahmood, Tanveer

    2017-03-01

    Flow Doppler imaging is widely used by clinicians to detect diseases of the valves. In particular, continuous wave (CW) Doppler mode scan is routinely done during echocardiography and shows Doppler signal traces over multiple heart cycles. Traditionally, echocardiographers have manually traced such velocity envelopes to extract measurements such as decay time and pressure gradient which are then matched to normal and abnormal values based on clinical guidelines. In this paper, we present a fully automatic approach to deriving these measurements for aortic stenosis retrospectively from echocardiography videos. Comparison of our method with measurements made by echocardiographers shows large agreement as well as identification of new cases missed by echocardiographers.

  2. Meiotic abnormalities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-12-31

    Chapter 19, describes meiotic abnormalities. These include nondisjunction of autosomes and sex chromosomes, genetic and environmental causes of nondisjunction, misdivision of the centromere, chromosomally abnormal human sperm, male infertility, parental age, and origin of diploid gametes. 57 refs., 2 figs., 1 tab.

  3. Is Doppler ultrasound useful for evaluating gestational trophoblastic disease?

    Directory of Open Access Journals (Sweden)

    Lawrence H. Lin

    Full Text Available Doppler ultrasound is a non-invasive method for evaluating vascularization and is widely used in clinical practice. Gestational trophoblastic neoplasia includes a group of highly vascularized malignancies derived from placental cells. This review summarizes data found in the literature regarding the applications of Doppler ultrasound in managing patients with gestational trophoblastic neoplasia. The PubMed/Medline, Web of Science, Cochrane and LILACS databases were searched for articles published in English until 2014 using the following keywords: “Gestational trophoblastic disease AND Ultrasonography, Doppler.” Twenty-eight articles met the inclusion criteria and were separated into the 4 following groups according to the aim of the study. (1 Doppler ultrasound does not seem to be capable of differentiating partial from complete moles, but it might be useful when evaluating pregnancies in which a complete mole coexists with a normal fetus. (2 There is controversy in the role of uterine artery Doppler velocimetry in the prediction of development of gestational trophoblastic neoplasia. (3 Doppler ultrasound is a useful tool in the diagnosis of gestational trophoblastic neoplasia because abnormal myometrial vascularization and lower uterine artery Doppler indices seem to be correlated with invasive disease. (4 Lower uterine artery Doppler indices in the diagnosis of gestational trophoblastic neoplasia are associated with methotrexate resistance and might play a role in prognosis. CONCLUSION: Several studies support the importance of Doppler ultrasound in the management of patients with gestational trophoblastic neoplasia, particularly the role of Doppler velocimetry in the prediction of trophoblastic neoplasia and the chemoresistance of trophoblastic tumors. Doppler findings should be used as ancillary tools, along with human chorionic gonadotropin assessment, in the diagnosis of gestational trophoblastic neoplasia.

  4. Is Doppler ultrasound useful for evaluating gestational trophoblastic disease?

    Science.gov (United States)

    Lin, Lawrence H; Bernardes, Lisandra S; Hase, Eliane A; Fushida, Koji; Francisco, Rossana P V

    2015-12-01

    Doppler ultrasound is a non-invasive method for evaluating vascularization and is widely used in clinical practice. Gestational trophoblastic neoplasia includes a group of highly vascularized malignancies derived from placental cells. This review summarizes data found in the literature regarding the applications of Doppler ultrasound in managing patients with gestational trophoblastic neoplasia. The PubMed/Medline, Web of Science, Cochrane and LILACS databases were searched for articles published in English until 2014 using the following keywords: "Gestational trophoblastic disease AND Ultrasonography, Doppler." Twenty-eight articles met the inclusion criteria and were separated into the 4 following groups according to the aim of the study. (1) Doppler ultrasound does not seem to be capable of differentiating partial from complete moles, but it might be useful when evaluating pregnancies in which a complete mole coexists with a normal fetus. (2) There is controversy in the role of uterine artery Doppler velocimetry in the prediction of development of gestational trophoblastic neoplasia. (3) Doppler ultrasound is a useful tool in the diagnosis of gestational trophoblastic neoplasia because abnormal myometrial vascularization and lower uterine artery Doppler indices seem to be correlated with invasive disease. (4) Lower uterine artery Doppler indices in the diagnosis of gestational trophoblastic neoplasia are associated with methotrexate resistance and might play a role in prognosis. Several studies support the importance of Doppler ultrasound in the management of patients with gestational trophoblastic neoplasia, particularly the role of Doppler velocimetry in the prediction of trophoblastic neoplasia and the chemoresistance of trophoblastic tumors. Doppler findings should be used as ancillary tools, along with human chorionic gonadotropin assessment, in the diagnosis of gestational trophoblastic neoplasia.

  5. Congenital Abnormalities

    Science.gov (United States)

    ... Ribbon Commands Skip to main content Turn off Animations Turn on Animations Our Sponsors Log in | Register Menu Log in | ... course of action. Additional Information Your Family Health History & Genetics Detecting Genetic Abnormalities Prenatal Genetic Counseling Children ...

  6. Walking abnormalities

    Science.gov (United States)

    ... with short-term or long-term gait disorders. Therapy will reduce the risk of falls and other injuries. For an abnormal gait that occurs with conversion disorder, counseling and support from family members are ...

  7. Cyclic variation of Doppler power as a function of hematocrit and vessel wall compliance

    DEFF Research Database (Denmark)

    Misaridis, Athanasios; Shung, K.K.

    1998-01-01

    In order to better understand the relationship between the power of the Doppler spectrum and blood flow abnormalities, a systematic study of all factors that may affect the Doppler power is required. In the study, three important factors were investigated in vitro using a mock flow loop: a) the p...

  8. Delivery of enteral nutrition.

    Science.gov (United States)

    Grant, M J; Martin, S

    2000-11-01

    There is increasing evidence that enteral feeding is superior to parenteral nutrition with regard to maintaining gut structure and function. Selection of the enteral access route depends on the type and anticipated duration of nutrient delivery. At present, enteral feeding devices can be divided into two major categories: those entering the gastrointestinal tract through the oral or nasal cavity (oroenteric or nasoenteric tubes) and those entering through the abdominal wall including gastrostomy, duodenostomy, or jejunostomy tubes. This article provides a review of methods to insert and confirm gastric and intestinal feeding tube placement. Care of the patient with an enteric tube will be described.

  9. Ultrasonic colour Doppler imaging

    DEFF Research Database (Denmark)

    Evans, David H; Jensen, Jørgen Arendt; Nielsen, Michael Bachmann

    2011-01-01

    anatomy. The most common use of the technique is to image the movement of blood through the heart, arteries and veins, but it may also be used to image the motion of solid tissues such as the heart walls. Colour Doppler imaging is now provided on almost all commercial ultrasound machines, and has been...... vectors. This review briefly introduces the principles behind colour Doppler imaging and describes some clinical applications. It then describes the basic components of conventional colour Doppler systems and the methods used to derive velocity information from the ultrasound signal. Next, a number of new...... techniques that seek to overcome the vector problem mentioned above are described. Finally, some examples of vector velocity images are presented....

  10. Penile Doppler ultrasonography revisited

    Directory of Open Access Journals (Sweden)

    Dae Chul Jung

    2018-01-01

    Full Text Available Penile Doppler ultrasonography is a high-performing, noninvasive or minimally-invasive imaging modality that allows the depiction of the normal anatomy and macroscopic pathologic changes in real time. Moreover, functional changes in penile blood flow, as seen in erectile dysfunction (ED, can be analyzed using color Doppler ultrasonography (CDUS. This review article describes the normal sonographic anatomy of the penis, the sonographic technique for evaluating ED, the normal phases of erection, and the various causes of ED. Additionally, we describe the interpretation of different parameters and findings on penile CDUS for the diagnosis and classification of ED, priapism, and Peyronie disease.

  11. Doppler radar physiological sensing

    CERN Document Server

    Lubecke, Victor M; Droitcour, Amy D; Park, Byung-Kwon; Singh, Aditya

    2016-01-01

    Presents a comprehensive description of the theory and practical implementation of Doppler radar-based physiological monitoring. This book includes an overview of current physiological monitoring techniques and explains the fundamental technology used in remote non-contact monitoring methods. Basic radio wave propagation and radar principles are introduced along with the fundamentals of physiological motion and measurement. Specific design and implementation considerations for physiological monitoring radar systems are then discussed in detail. The authors address current research and commercial development of Doppler radar based physiological monitoring for healthcare and other applications.

  12. Pulse Doppler radar

    CERN Document Server

    Alabaster, Clive

    2012-01-01

    This book is a practitioner's guide to all aspects of pulse Doppler radar. It concentrates on airborne military radar systems since they are the most used, most complex, and most interesting of the pulse Doppler radars; however, ground-based and non-military systems are also included. It covers the fundamental science, signal processing, hardware issues, systems design and case studies of typical systems. It will be a useful resource for engineers of all types (hardware, software and systems), academics, post-graduate students, scientists in radar and radar electronic warfare sectors and milit

  13. Scanning laser Doppler vibrometry

    DEFF Research Database (Denmark)

    Brøns, Marie; Thomsen, Jon Juel

    With a Scanning Laser Doppler Vibrometer (SLDV) a vibrating surface is automatically scanned over predefined grid points, and data processed for displaying vibration properties like mode shapes, natural frequencies, damping ratios, and operational deflection shapes. Our SLDV – a PSV-500H from...

  14. Adaptive Spectral Doppler Estimation

    DEFF Research Database (Denmark)

    Gran, Fredrik; Jakobsson, Andreas; Jensen, Jørgen Arendt

    2009-01-01

    In this paper, 2 adaptive spectral estimation techniques are analyzed for spectral Doppler ultrasound. The purpose is to minimize the observation window needed to estimate the spectrogram to provide a better temporal resolution and gain more flexibility when designing the data acquisition sequence...

  15. The Doppler Pendulum Experiment

    Science.gov (United States)

    Lee, C. K.; Wong, H. K.

    2011-01-01

    An experiment to verify the Doppler effect of sound waves is described. An ultrasonic source is mounted at the end of a simple pendulum. As the pendulum swings, the rapid change of frequency can be recorded by a stationary receiver using a simple frequency-to-voltage converter. The experimental results are in close agreement with the Doppler…

  16. Environmental enteric dysfunction is associated with altered bile acid metabolism

    Science.gov (United States)

    Environmental enteric dysfunction (EED), a clinically asymptomatic condition characterized by inflammation of the small bowel mucosa, villous atrophy, and increased gut permeability, is common among children in developing countries. Because of abnormal gut mucosa and altered gut microbiome, EED coul...

  17. Uterine artery Doppler flow studies in obstetric practice.

    Science.gov (United States)

    Sciscione, Anthony C; Hayes, Edward J

    2009-08-01

    The advent of sonography has changed the practice of obstetrics by providing a window to the womb through which the anatomic structure of the fetus can be evaluated. The addition of Doppler flow studies of maternal and fetal vessels has provided a tool where the physiology of the maternal-fetal unit can be assessed. This information can provide the physician and the patient with vital information for a subsequent approach to the pregnancy. The use of fetal Doppler blood flow studies has become common in the evaluation and management of pregnancies complicated by conditions such as suspected fetal growth restriction and red blood cell isoimmunization to guide intrauterine therapy and delivery. The most commonly assessed Doppler flow studies of the fetus are the umbilical artery and middle cerebral artery (MCA). Doppler flow studies of the MCA are used in the assessment of the fetus at risk for anemia and growth-restricted fetus. Doppler flow studies of the umbilical artery can reflect abnormalities in "down-stream" or the fetal side of placental resistance, and the assessment of the maternal vasculature evaluates "up-stream" blood flow or the maternal side of placental resistance. The purpose of this review is to describe the clinical utility of uterine artery Doppler flow studies in the prediction of adverse pregnancy outcomes in low and high risk populations.

  18. Doppler ultrasound exam of an arm or leg

    Science.gov (United States)

    ... related deaths are caused by cardiovascular problems, not lung cancer. Alternative Names Peripheral vascular disease - Doppler; PVD - Doppler; PAD - Doppler; Blockage of leg arteries - Doppler; Intermittent claudication - Doppler; Arterial insufficiency of the legs - Doppler; Leg pain and cramping - ...

  19. Laser Doppler anemometry

    Science.gov (United States)

    Johnson, Dennis A.

    1988-01-01

    The material in this NASA TM is to appear as a chapter on Laser Doppler Anemometry (LDA) in the AGARDograph entitled, A Survey of Measurements and Measuring Techniques in Rapidly Distorted Compressible Turbulent Boundary Layers. The application of LDA (specifically, the dual-beam, burst-counter approach) to compressible flows is discussed. Subjects treated include signal processing, particle light scattering and tracking, data reduction and sampling bias, and three-dimensional measurements.

  20. What Is Enteral Nutrition?

    Science.gov (United States)

    ... pharmacists) will talk with you about the different types of feeding tubes. Enteral Nutrition Fact Sheet ... Continuing Education Certification Claim CE Credits ASPEN 2018 Nutrition Science and ...

  1. Doppler Optical Coherence Tomography

    Science.gov (United States)

    Leitgeb, Rainer A.; Werkmeister, René M.; Blatter, Cedric; Schmetterer, Leopold

    2014-01-01

    Optical Coherence Tomography (OCT) has revolutionized ophthalmology. Since its introduction in the early 1990s it has continuously improved in terms of speed, resolution and sensitivity. The technique has also seen a variety of extensions aiming to assess functional aspects of the tissue in addition to morphology. One of these approaches is Doppler OCT (DOCT), which aims to visualize and quantify blood flow. Such extensions were already implemented in time domain systems, but have gained importance with the introduction of Fourier domain OCT. Nowadays phase-sensitive detection techniques are most widely used to extract blood velocity and blood flow from tissues. A common problem with the technique is that the Doppler angle is not known and several approaches have been realized to obtain absolute velocity and flow data from the retina. Additional studies are required to elucidate which of these techniques is most promising. In the recent years, however, several groups have shown that data can be obtained with high validity and reproducibility. In addition, several groups have published values for total retinal blood flow. Another promising application relates to non-invasive angiography. As compared to standard techniques such as fluorescein and indocyanine-green angiography the technique offers two major advantages: no dye is required and depth resolution is required is provided. As such Doppler OCT has the potential to improve our abilities to diagnose and monitor ocular vascular diseases. PMID:24704352

  2. Color Doppler US of superficial adenopathies; Il color Doppler nelle adenopatie superficiali

    Energy Technology Data Exchange (ETDEWEB)

    Giovagnorio, F. [Rome Univ. (Italy). 1. Cattedra di Radiologia

    1999-03-01

    Superficial lymph node are frequently involved in different diseases. Their location makes them suitable for effective assessment with high-resolution US and color Doppler has been recently suggested as a tool for increasing sensitivity in lymph node studies. Thus the author investigated the main vascular patterns detectable in abnormal superficial lymph nodes. [Italian] Numerosa malattie con natura differente coinvolgono i linfonodi superficiali: la localizzazione ne consente l'esplorazione con ecografia con alta risoluzione e lo studio mediante eco color Doppler e' stato proposto negli ultimi anni incontrando notevole sviluppo in tempi recenti. Scopo del lavoro e' illustrare il contributo personale nella definizione dei principali quadri riscontrabili nelle diverse adenopatie superficiali.

  3. Monitoring and Analysis of Respiratory Patterns Using Microwave Doppler Radar

    Science.gov (United States)

    Pathirana, Pubudu N.; Steinfort, Christopher Louis; Caelli, Terry

    2014-01-01

    Noncontact detection characteristic of Doppler radar provides an unobtrusive means of respiration detection and monitoring. This avoids additional preparations, such as physical sensor attachment or special clothing, which can be useful for certain healthcare applications. Furthermore, robustness of Doppler radar against environmental factors, such as light, ambient temperature, interference from other signals occupying the same bandwidth, fading effects, reduce environmental constraints and strengthens the possibility of employing Doppler radar in long-term respiration detection, and monitoring applications such as sleep studies. This paper presents an evaluation in the of use of microwave Doppler radar for capturing different dynamics of breathing patterns in addition to the respiration rate. Although finding the respiration rate is essential, identifying abnormal breathing patterns in real-time could be used to gain further insights into respiratory disorders and refine diagnostic procedures. Several known breathing disorders were professionally role played and captured in a real-time laboratory environment using a noncontact Doppler radar to evaluate the feasibility of this noncontact form of measurement in capturing breathing patterns under different conditions associated with certain breathing disorders. In addition to that, inhalation and exhalation flow patterns under different breathing scenarios were investigated to further support the feasibility of Doppler radar to accurately estimate the tidal volume. The results obtained for both experiments were compared with the gold standard measurement schemes, such as respiration belt and spirometry readings, yielding significant correlations with the Doppler radar-based information. In summary, Doppler radar is highlighted as an alternative approach not only for determining respiration rates, but also for identifying breathing patterns and tidal volumes as a preferred nonwearable alternative to the conventional

  4. Immediate preoperative enteral nutrition (preoperative enteral nutrition

    Directory of Open Access Journals (Sweden)

    Lađević Nebojša

    2017-01-01

    Full Text Available Nutritional support of surgical patients is a necessary part of the treatment. It alone cannot cure the disease but it significantly affects the recovery of patients and supports surgical interventions. Patients in malnutrition have shown to have significantly more postoperative infectious and non-infectious complications. This significantly prolongs treatment time and increases costs. However, there is one fact that cannot be expressed in money, which is the patient's impression of the surgical intervention. Adequate preoperative patient support, based on the intake of liquid nutritive solutions, reduces preoperative stress and deflects the metabolic response. Now, it is recommended for adults and children older than one year to drink clear liquid up to 2 hours before induction in anesthesia. Appropriate enteral nutrition has a significant place in the postoperative recovery of patients. Enteral nutrition is reducing complications, mainly infectious complications because the function of the digestive system as one large immune system is preserved. Perioperative enteral nutrition is a necessary part of the modern treatment of surgical patients. In addition to the significant effect on the occurrence of postoperative complications, it is also important that this type of diet improves the psychological status of patients.

  5. Enteric neurodegeneration in ageing.

    Science.gov (United States)

    Camilleri, M; Cowen, T; Koch, T R

    2008-04-01

    The objective of this article is to review the clinical presentation and neurobiology of degeneration of the enteric nervous system with emphasis on human data where available. Constipation, incontinence and evacuation disorders are frequently encountered in the ageing population. Healthy lower gastrointestinal function is essential for successful ageing as it is critical to maintaining independence and autonomy to pursue further activity. One clinical expression of enteric neurodegeneration is constipation. However, the aetiology may be multifactorial as disturbances of epithelial, muscle or neural function may all result from neurodegeneration. There is evidence of loss of excitatory (e.g. cholinergic) enteric neurons and interstitial cells of Cajal, whereas inhibitory (including nitrergic) neurons appear unaffected. Understanding neurodegeneration in the enteric nervous system is key to developing treatments to reverse it. Neurotrophins have been shown to accelerate colonic transit and relieve constipation in the medium term; they are also implicated in maintenance programmes in adult enteric neurons through a role in antioxidant defence. However, their effects in ageing colon require further study. There is evidence that 5-HT(2) and 5-HT(4) mechanisms are involved in development, maintenance and survival of enteric neurons. Further research is needed to understand and potentially reverse enteric neurodegeneration.

  6. Comparisons between PW Doppler system and enhanced FM Doppler system

    DEFF Research Database (Denmark)

    Wilhjelm, Jens E.; Pedersen, P. C.

    1995-01-01

    This paper presents a new implementation of an echo-ranging FM Doppler system with improved performance, relative to the FM Doppler system reported previously. The use of long sweeps provides a significant reduction in peak to average power ratio compared to pulsed wave (PW) emission. A PW Doppler...... system exploits the direct relationship between arrival time of the received signal and range from the transducer. In the FM Doppler systems, a similar relationship exists in the spectral domain of the demodulated received signals, so that range is represented by frequency. Thus, a shift in location...... of moving scatterers between consecutive emissions corresponds to a frequency shift in the spectral signature. The improvement relative to the earlier version of the FM Doppler system is attained by utilizing cross-correlation of real spectra rather than of magnitude spectra for assessing flow velocity...

  7. The enteric nervous system

    National Research Council Canada - National Science Library

    Sasselli, Valentina; Pachnis, Vassilis; Burns, Alan J

    2012-01-01

    The enteric nervous system (ENS), the intrinsic innervation of the gastrointestinal tract, consists of numerous types of neurons, and glial cells, that are distributed in two intramuscular plexuses that extend along the entire...

  8. Hyperemia in plantar fasciitis determined by power Doppler ultrasound.

    Science.gov (United States)

    McMillan, Andrew M; Landorf, Karl B; Gregg, Julie M; De Luca, Jason; Cotchett, Matthew P; Menz, Hylton B

    2013-12-01

    Cross-sectional observational study. To investigate the presence of soft tissue hyperemia in plantar fasciitis with power Doppler ultrasound. Localized hyperemia is an established feature of tendinopathy, suggesting that neurovascular in-growth may contribute to tendon-associated pain in some patients. The presence of abnormal soft tissue vascularity can be assessed with Doppler ultrasound, and a positive finding can assist with targeted treatment plans. However, very little is known regarding the presence of hyperemia in plantar fasciitis and the ability of routine Doppler ultrasound to identify vascular in-growth in the plantar fascia near its proximal insertion. This observational study included 30 participants with plantar fasciitis unrelated to systemic disease and 30 age- and sex-matched controls. Ultrasound examination was performed with a 13- to 5-MHz linear transducer, and power Doppler images were assessed by 2 blinded investigators. Hyperemia of the plantar fascia was present in 8 of 30 participants with plantar fasciitis and in 2 of 30 controls. The between-group difference for hyperemia, using a 4-point scale, was statistically significant, with participants with plantar fasciitis showing increased Doppler ultrasound signal compared to controls (Mann-Whitney U, P = .03). However, the majority of participants with plantar fasciitis with evidence of hyperemia demonstrated very mild color changes, and only 3 were found to have moderate or marked hyperemia. Mild hyperemia can occur with plantar fasciitis, but most individuals will not exhibit greater soft tissue vascularity when assessed with routine Doppler ultrasound. Clinicians treating plantar fasciitis should not consider a positive Doppler signal as essential for diagnosis of the condition but, rather, as a feature that may help to refine the treatment plan for an individual patient.

  9. Hepatic arterial waveforms on early posttransplant Doppler ultrasound.

    Science.gov (United States)

    Hedegard, Wade C; Bhatt, Shweta; Saad, Wael; Rubens, Deborah; Dogra, Vikram

    2011-03-01

    To determine the significance of spectral Doppler hepatic artery waveforms obtained in the first 10 days after primary liver transplantation and to determine the best early predictor of hepatic arterial thrombosis (HAT). A total of 645 patients were retrospectively followed up to 1 year after liver transplantation. Doppler waveforms of the hepatic arteries were categorized as normal, abnormally elevated, not visualized, or with resistive index (RI) hepatic artery on Doppler evaluation and 56 (8.7%) developed HAT or stenosis within the first year after transplantation. Odds ratios (ORs) demonstrate that a single nonvisualized hepatic artery (OR, 9.66; 95% confidence interval [CI], 4.51-20.70) has a much higher incidence of HAT in the first 10 days after transplantation compared to low RI (OR, 1.93; 95% CI, 0.77-4.79)] or high RI (OR, 1.06; 95% CI, 0.44-2.55]. The loss or reversal of diastolic flow on Doppler ultrasound performed in the first 10 days after transplantation does not seem to correlate with active or impending HAT. Absence of hepatic arterial flow Doppler signal in the first 10 days after liver transplantation is associated with higher incidence of thrombosis than previously demonstrated, whereas persistently high diastolic flow early on seems to be more significant and leads to further hepatic arterial complications than decreased diastolic flow.

  10. Laser Doppler Imaging of Microflow

    CERN Document Server

    Gross, Michel; Leng, Jacques

    2013-01-01

    We report a pilot study with a wide-field laser Doppler detection scheme used to perform laser Doppler anemometry and imaging of particle seeded microflow. The optical field carrying the local scatterers (particles) dynamic state, as a consequence of momentum transfer at each scattering event, is analyzed in the temporal frequencies domain. The setup is based on heterodyne digital holography, which is used to map the scattered field in the object plane at a tunable frequency with a multipixel detector. We show that wide-field heterodyne laser Doppler imaging can be used for quantitative microflow diagnosis; in the presented study, maps of the first-order moment of the Doppler frequency shift are used as a quantitative and directional estimator of the Doppler signature of particles velocity.

  11. Uterine-umbilical artery Doppler velocimetry in pregnant women with systemic lupus erythematosus.

    Science.gov (United States)

    Guzman, E; Schulman, H; Bracero, L; Rochelson, B; Farmakides, G; Coury, A

    1992-06-01

    We evaluated continuous wave uterine-umbilical artery Doppler velocimetry for predicting pregnancy outcome in women with systemic lupus erythematosus (SLE). Lupus anticoagulant (LAC) and anticardiolipin (ACL) antibody status also were correlated with Doppler results and outcome. Three Doppler vascular patterns were identified in 27 pregnancies of 26 women with SLE. Patients with normal flow velocity in both vessels had normal outcomes (n = 18). Reduced flow velocity of the umbilical artery only was present in five women, whose newborn infants were of lesser gestational age and birthweight, two being small for gestational age. In four pregnancies reduced flow velocity was noted in both vessels. These cases had the poorest outcome, with three perinatal losses and all fetuses being small for gestational age. Doppler velocimetry showed 100% sensitivity and negative predictive value in the detection of the small for gestational age fetus and abnormal antepartum fetal heart rate tracing. Fourteen of 18 women with normal Doppler studies did not have preeclampsia or SLE flare-ups, whereas all nine women with abnormal Doppler studies had such complications. In all 27 pregnancies the women were screened for LAC, and 21 women also were tested for the ACL antibody. Poor correlation was found between antiphospholipid antibody status and Doppler results in three of the six pregnancies with positive antibody testing the patients had normal Doppler studies and outcomes. Thus, Doppler velocimetry may help determine when these substances will affect the outcome adversely. In this study the umbilical-placental vascular system was affected more often. Uterine-umbilical arterial Doppler velocimetry uniquely identified the fetus at risk for adverse perinatal outcome in pregnancies complicated by SLE. Thus, it is a potentially valuable tool in clarifying the pathophysiology and in the management of SLE in pregnancy.

  12. ENFit Enteral Nutrition Connectors.

    Science.gov (United States)

    Guenter, Peggi; Lyman, Beth

    2016-12-01

    New enteral connectors are now available based on the development of standards using the International Organization of Standardization process to prevent misconnections between systems that should not connect. Enteral devices with the new patient access connectors, called ENFit, are being now introduced for the purpose of improving patient safety. Transitioning to these new connectors poses benefits and challenges for facilities or agencies implementing these new devices. Information from appropriate resources should be sought by clinicians who need to partner with their suppliers and clinical organizations to see how best to meet these challenges.

  13. 5. Enter Bernhard Riemann

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 6. Geometry Enter Bernhard Riemann. Kapil H Paranjape. Series Article Volume 1 Issue 6 June 1996 pp 33-40. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/001/06/0033-0040. Author Affiliations.

  14. Intestinal endocrine cells in radiation enteritis

    Energy Technology Data Exchange (ETDEWEB)

    Pietroletti, R.; Blaauwgeers, J.L.; Taat, C.W.; Simi, M.; Brummelkamp, W.H.; Becker, A.E. (Academic Medical Centre, Amsterdam (Netherlands))

    1989-08-01

    In this study, the intestinal endocrine cells were investigated in 13 surgical specimens affected by radiation enteritis. Endocrine cells were studied by means of Grimelius' silver staining and immunostaining for chromogranin, a general marker of endocrine cells. Positively stained cells were quantified by counting their number per unit length of muscularis mucosa. Results in radiation enteritis were compared with matched control specimens by using Student's t test. Chromogranin immunostaining showed a statistically significant increase of endocrine cells in radiation enteritis specimens compared with controls both in small and large intestine (ileum, 67.5 +/- 23.5 cells per unit length of muscularis mucosa in radiation enteritis versus 17.0 +/- 6.1 in controls; colon, 40.9 +/- 13.7 cells per unit length of muscularis mucosa in radiation enteritis versus 9.5 +/- 4.1 in controls--p less than 0.005 in both instances). Increase of endocrine cells was demonstrated also by Grimelius' staining; however, without reaching statistical significance. It is not clear whether or not the increase of endocrine cells in radiation enteritis reported in this study is caused by a hyperplastic response or by a sparing phenomenon. We should consider that increased endocrine cells, when abnormally secreting their products, may be involved in some of the clinical features of radiation enteropathy. In addition, as intestinal endocrine cells produce trophic substances to the intestine, their increase could be responsible for the raised risk of developing carcinoma of the intestine in long standing radiation enteritis.

  15. Dual-Doppler Feasibility Study

    Science.gov (United States)

    Huddleston, Lisa L.

    2012-01-01

    When two or more Doppler weather radar systems are monitoring the same region, the Doppler velocities can be combined to form a three-dimensional (3-D) wind vector field thus providing for a more intuitive analysis of the wind field. A real-time display of the 3-D winds can assist forecasters in predicting the onset of convection and severe weather. The data can also be used to initialize local numerical weather prediction models. Two operational Doppler Radar systems are in the vicinity of Kennedy Space Center (KSC) and Cape Canaveral Air Force Station (CCAFS); these systems are operated by the 45th Space Wing (45 SW) and the National Weather Service Melbourne, Fla. (NWS MLB). Dual-Doppler applications were considered by the 45 SW in choosing the site for the new radar. Accordingly, the 45th Weather Squadron (45 WS), NWS MLB and the National Aeronautics and Space Administration tasked the Applied Meteorology Unit (AMU) to investigate the feasibility of establishing dual-Doppler capability using the two existing systems. This study investigated technical, hardware, and software requirements necessary to enable the establishment of a dual-Doppler capability. Review of the available literature pertaining to the dual-Doppler technique and consultation with experts revealed that the physical locations and resulting beam crossing angles of the 45 SW and NWS MLB radars make them ideally suited for a dual-Doppler capability. The dual-Doppler equations were derived to facilitate complete understanding of dual-Doppler synthesis; to determine the technical information requirements; and to determine the components of wind velocity from the equation of continuity and radial velocity data collected by the two Doppler radars. Analysis confirmed the suitability of the existing systems to provide the desired capability. In addition, it is possible that both 45 SW radar data and Terminal Doppler Weather Radar data from Orlando International Airport could be used to alleviate any

  16. Doppler characteristics of sea clutter.

    Energy Technology Data Exchange (ETDEWEB)

    Raynal, Ann Marie; Doerry, Armin Walter

    2010-06-01

    Doppler radars can distinguish targets from clutter if the target's velocity along the radar line of sight is beyond that of the clutter. Some targets of interest may have a Doppler shift similar to that of clutter. The nature of sea clutter is different in the clutter and exo-clutter regions. This behavior requires special consideration regarding where a radar can expect to find sea-clutter returns in Doppler space and what detection algorithms are most appropriate to help mitigate false alarms and increase probability of detection of a target. This paper studies the existing state-of-the-art in the understanding of Doppler characteristics of sea clutter and scattering from the ocean to better understand the design and performance choices of a radar in differentiating targets from clutter under prevailing sea conditions.

  17. Statement for Doppler waveforms analysis.

    Science.gov (United States)

    Mahé, Guillaume; Boulon, Carine; Desormais, Ileana; Lacroix, Philippe; Bressollette, Luc; Guilmot, Jean-Louis; Le Hello, Claire; Sevestre, Marie-Antoinette; Pernod, Gilles; Constans, Joel; Boissier, Christian; Bura-Rivière, Alessandra

    2017-08-01

    Peripheral artery disease of the lower limbs (PAD) is a common disease. Evaluation of PAD is primarily based on non-invasive examinations with analysis of the arterial Doppler signal being a key element. However, the description of arterial Doppler waveforms morphologies varies considerably across medical schools and from country to country. In order to overcome this issue, the French College of Teachers for Vascular Medicine (Collège des Enseignants de Médecine Vasculaire; CEMV) has summarised the published data on Doppler waveforms analysis and proposes a new "Saint-Bonnet" classification system to describe Doppler waveforms morphologies. The simplified Saint-Bonnet classification comprises eight types and allows taking into account if the Doppler signal does not revert to baseline. This classification, which is based on previous classifications, could improve the descriptions of both physiological and pathological waveforms, recorded in lower limb arteries. According to the reviewed literature, recommendations about the use of Doppler waveforms are proposed. This statement is a preamble to reach an international consensus on the subject, which would standardize the description of arterial waveforms and improve the management of PAD patients.

  18. Color and power Doppler combined with Fetal Intelligent Navigation Echocardiography (FINE) to evaluate the fetal heart.

    Science.gov (United States)

    Yeo, L; Romero, R

    2017-10-01

    with appropriate color and S-flow Doppler information was 89-100% and 91-100% of cases, respectively, using a combination of diagnostic planes and/or VIS-Assistance. However, the success rate for the ninth echocardiography view (i.e. superior and inferior venae cavae) was 33% and 30% for color and S-flow Doppler, respectively. In all four cases of CHD, color Doppler FINE demonstrated evidence of abnormal fetal cardiac anatomy and/or hemodynamic flow. The FINE method applied to STIC volumes of normal fetal hearts acquired with color or bidirectional power Doppler information can generate successfully eight to nine standard fetal echocardiography views (via grayscale, color Doppler or power Doppler) in the second and third trimesters. In cases of CHD, color Doppler FINE demonstrates successfully abnormal anatomy and/or Doppler flow characteristics. Published 2017. This article is a U.S. Government work and is in the public domain in the USA. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of the International Society of Ultrasound in Obstetrics and Gynecology. Published 2017. This article is a U.S. Government work and is in the public domain in the USA. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of the International Society of Ultrasound in Obstetrics and Gynecology.

  19. Doppler echocardiographic evaluation of HIV-positive patients in different stages of the disease

    Directory of Open Access Journals (Sweden)

    Werneck Guilherme Lobosco

    1999-01-01

    Full Text Available OBJETIVE: To evaluate by Doppler echocardiography (DE early abnormalities of ventricular function in HIV-positive patients, as well as other cardiac abnormalities that can be detected by this method, with special emphasis on mitral valve flow. METHODS: 84 HIV- positive patients, 59 with CD4 cell count >500/mm³ (Group A and 25 with CD4 cell count 500/mm³ had no abnormalities by DE. Patients with a more advanced infection (those with a CD4 cell count <500/mm³, had a significantly abnormal LV systolic function and a higher incidence of pericardial effusion and mitral regurgitation. Mitral valve inflow by Doppler did not indicate diastolic dysfunction.

  20. General principles of carotid Doppler ultrasonography

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Whal [Dept. of Radiology, Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2014-03-15

    Carotid Doppler ultrasonography is a popular tool for evaluating atherosclerosis of the carotid artery. Its two-dimensional gray scale can be used for measuring the intima-media thickness, which is very good biomarker for atherosclerosis and can aid in plaque characterization. The plaque morphology is related to the risk of stroke. The ulceration of plaque is also known as one of the strong predictors of future embolic event risk. Color Doppler ultrasonography and pulse Doppler ultrasonography have been used for detecting carotid artery stenosis. Doppler ultrasonography has unique physical properties. The operator should be familiar with the physics and other parameters of Doppler ultrasonography to perform optimal Doppler ultrasonography studies.

  1. Enteral nutrition - child - managing problems

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000164.htm Enteral nutrition - child - managing problems To use the sharing features ... trouble breathing, call 911. References Mcclave SA. Enteral nutrition. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  2. Inverse Doppler Effects in Flute

    CERN Document Server

    Zhao, Xiao P; Liu, Song; Shen, Fang L; Li, Lin L; Luo, Chun R

    2015-01-01

    Here we report the observation of the inverse Doppler effects in a flute. It is experimentally verified that, when there is a relative movement between the source and the observer, the inverse Doppler effect could be detected for all seven pitches of a musical scale produced by a flute. Higher tone is associated with a greater shift in frequency. The effect of the inverse frequency shift may provide new insights into why the flute, with its euphonious tone, has been popular for thousands of years in Asia and Europe.

  3. Duplex/doppler ultrasound test (image)

    Science.gov (United States)

    The duplex/doppler ultrasound test examines the blood flow in the major arteries and veins in the arms and legs. The ... duplex ultrasonagraphy to visualize the blood flow and doppler ultrasonagraphy provides an audio means to hear the ...

  4. [Fiber and enteral nutrition].

    Science.gov (United States)

    Gómez Candela, C; de Cos Blanco, A I; Iglesias Rosado, C

    2002-01-01

    Dietary fibre is a mixture of various substances and is essential for maintaining appropriate intestinal functionality and it is currently considered to be a necessary part of a healthy diet. Current recommendations for fibre consumption by adults range from 20 to 35 g/day. Enteral nutrition is an emerging therapeutic variation in both hospital and domestic settings. To a great extent, this development has been made possible thanks to the design of new formulas that adapt better and better to the clinicla conditions or our patients. The type of fibre used in these preparations varies greatly. Some have only one source of fibre while others use differnet combinations. There are currently 32 formulas available on the Spanish market, without counting the modules or specific preparations of individual types of fibre. Despite the enormous advances in the knowledge of the beneficial effects of fibre, the fact of the matter is that enteral nutrition that we routinely prescribe in normal clinical practice does not contain fibre. The are several explanations for this, perhaps the most plausible is that these formulas may lead to problems in their administration and tolerance. It is necessary to choose the correct calibre of catheter and define the best infusion method and timing. Another difficulty may be the gastrointestinal tolerance of the formulas containing fibre. No large-scale problems of intolerance have however been described in healthy volunteers nor in patients with acute or chronic pathologies, although it is of fundamental importance to monitor the rhythm of depositions in all patients with enteral nutrition (EN) and ensure proper intake of liquids, which would also be useful to prevent occlusion of the catheter. The theoretical benefits of EN with fibre with a view to maintaining or improving normal intestinal structure and function are very varied. Nonetheless, it has noit yet been possible to prove many of these effects in controlled clinical trials. At the

  5. Understanding Doppler Broadening of Gamma Rays

    Energy Technology Data Exchange (ETDEWEB)

    Rawool-Sullivan, Mohini [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sullivan, John P. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-07-03

    Doppler-broadened gamma ray peaks are observed routinely in the collection and analysis of gamma-ray spectra. If not recognized and understood, the appearance of Doppler broadening can complicate the interpretation of a spectrum and the correct identification of the gamma ray-emitting material. We have conducted a study using a simulation code to demonstrate how Doppler broadening arises and provide a real-world example in which Doppler broadening is found. This report describes that study and its results.

  6. Enteral nutrition access devices.

    Science.gov (United States)

    Kwon, Richard S; Banerjee, Subhas; Desilets, David; Diehl, David L; Farraye, Francis A; Kaul, Vivek; Mamula, Petar; Pedrosa, Marcos C; Rodriguez, Sarah A; Varadarajulu, Shyam; Song, Louis-Michel Wong Kee; Tierney, William M

    2010-08-01

    The ASGE Technology Committee provides reviews of existing, new, or emerging endoscopic technologies that have an impact on the practice of GI endoscopy. Evidence-based methodology is used, performing a MEDLINE literature search to identify pertinent clinical studies on the topic and a MAUDE (U.S. Food and Drug Administration Center for Devices and Radiological Health) database search to identify the reported complications of a given technology. Both are supplemented by accessing the "related articles" feature of PubMed and by scrutinizing pertinent references cited by the identified studies. Controlled clinical trials are emphasized, but, in many cases, data from randomized, controlled trials are lacking. In such situations, large case series, preliminary clinical studies, and expert opinions are used. Technical data are gathered from traditional and Web-based publications, proprietary publications, and informal communications with pertinent vendors. Technology Status Evaluation Reports are drafted by 1 or 2 members of the ASGE Technology Committee, reviewed and edited by the committee as a whole, and approved by the ASGE Governing Board. When financial guidance is indicated, the most recent coding data and list prices at the time of publication are provided. For this review, the MEDLINE database was searched through August 2009 for articles related to endoscopy in patients requiring enteral feeding access by using the keywords "endoscopy," "percutaneous," "gastrostomy," "jejunostomy," "nasogastric," "nasoenteric," "nasojejunal," "transnasal," "feeding tube," "enteric," and "button." Technology Status Evaluation Reports are scientific reviews provided solely for educational and informational purposes. Technology Status Evaluation Reports are not rules and should not be construed as establishing a legal standard of care or as encouraging, advocating, requiring, or discouraging any particular treatment or payment for such treatment. Copyright 2010 American Society

  7. Micro-Doppler Analysis of Small UAVs

    NARCIS (Netherlands)

    Wit, J.J.M. de; Harmanny, R.I.A.; Prémel Cabic, G.

    2012-01-01

    Coherent radar measures micro-Doppler properties of moving objects. The micro-Doppler signature depends on parts of an object moving and rotating in addition to the main body motion (e.g. rotor blades) and is therefore characteristic for the type of object. In this study, the micro-Doppler signature

  8. Speckles in laser doppler perfusion imaging

    NARCIS (Netherlands)

    Rajan, V.V.

    2007-01-01

    Laser Doppler Flowmetry (LDF) is a noninvasive diagnostic method to measure blood flow in tissue [1]. The technique is based on measuring the Doppler shift induced by moving red blood cells to the illuminating coherent light. A laser Doppler instrument often gives output signals related to the flux,

  9. The Doppler Effect--A New Approach

    Science.gov (United States)

    Allen, J.

    1973-01-01

    Discusses the Doppler effect as it applies to different situations, such as a stationary source of sound with the observer moving, a stationary observer, and the sound source and observer both moving. Police radar, satellite surveillance radar, radar astronomy, and the Doppler navigator, are discussed as applications of Doppler shift. (JR)

  10. The aging colon: the role of enteric neurodegeneration in constipation.

    Science.gov (United States)

    Wiskur, Brandt; Greenwood-Van Meerveld, Beverley

    2010-12-01

    Constipation is a common problem in the elderly, and abnormalities in the neural innervation of the colon play a significant role in abnormalities in colonic motility leading to delayed colonic transit. The scope of this review encompasses the latest advances to enhance our understanding of the aging colon with emphasis on enteric neurodegeneration, considered a likely cause for the development of constipation in the aging gut in animal models. Neural innervation of the colon and the effects of aging on intrinsic and extrinsic nerves innervating the colonic smooth muscle is discussed. Evidence supporting the concept that neurologic disorders, such as Parkinson's disease, not only affect the brain but also cause neurodegeneration within the enteric nervous system leading to colonic dysmotility is presented. Further research is needed to investigate the influence of aging on the gastrointestinal tract and to develop novel approaches to therapy directed at protecting the enteric nervous system from neurodegeneration.

  11. [Modular enteral nutrition in pediatrics].

    Science.gov (United States)

    Murillo Sanchís, S; Prenafeta Ferré, M T; Sempere Luque, M D

    1991-01-01

    Modular Enteral Nutrition may be a substitute for Parenteral Nutrition in children with different pathologies. Study of 4 children with different pathologies selected from a group of 40 admitted to the Maternal-Childrens Hospital "Valle de Hebrón" in Barcelona, who received modular enteral nutrition. They were monitored on a daily basis by the Dietician Service. Modular enteral nutrition consists of modules of proteins, peptides, lipids, glucids and mineral salts-vitamins. 1.--Craneo-encephalic traumatisms with loss of consciousness, Feeding with a combination of parenteral nutrition and modular enteral nutrition for 7 days. In view of the tolerance and good results of the modular enteral nutrition, the parenteral nutrition was suspended and modular enteral nutrition alone used up to a total of 43 days. 2.--55% burns with 36 days of hyperproteic modular enteral nutrition together with normal feeding. A more rapid recovery was achieved with an increase in total proteins and albumin. 3.--Persistent diarrhoea with 31 days of modular enteral nutrition, 5 days on parenteral nutrition alone and 8 days on combined parenteral nutrition and modular enteral nutrition. In view of the tolerance and good results of the modular enteral nutrition, the parenteral nutrition was suspended. 4.--Mucoviscidosis with a total of 19 days on modular enteral nutrition, 12 of which were exclusively on modular enteral nutrition and 7 as a night supplement to normal feeding. We administered proteic intakes of up to 20% of the total calorific intake and in concentrations of up to 1.2 calories/ml of the final preparation, always with a good tolerance. Modular enteral nutrition can and should be used as a substitute for parenteral nutrition in children with different pathologies, thus preventing the complications inherent in parenteral nutrition.

  12. Use of Doppler velocimetry in diagnosis and prognosis of intrauterine growth restriction (IUGR): A Review.

    Science.gov (United States)

    Aditya, I; Tat, V; Sawana, A; Mohamed, A; Tuffner, R; Mondal, T

    2016-05-18

    Intrauterine growth restriction (IUGR) is a condition which has been difficult to assess at an early stage, resulting in the delivery of children who have poor genetic growth potential. Currently, IUGR classification is based upon the system of ultrasound biometry. Doppler velocimetry allows the measurement of hemodynamic flow of major fetal vessels, comparing the flow indices and patterns of normal and IUGR cases. In this review, the effectiveness of Doppler velocimetry in assessing blood flow in major vessels including the umbilical artery, ductus venosus, and middle cerebral artery was studied for both diagnostic and prognostic screening of IUGR. The umbilical artery is the most frequently studied vessel in Doppler velocimetry due to its accessibility and the strength of its associations with fetal outcomes. Abnormalities in the ductus venosus waveform can be indicative of increased resistance in the right atrium due to placental abnormalities. The middle cerebral artery is the most studied fetal cerebral artery and can detect cerebral blood flow and direction, which is why these three vessels were selected to be examined in this context. A potential mathematical model could be developed to incorporate these Doppler measurements which are indicative of IUGR, in order to reduce perinatal mortality. The purpose of the proposed algorithm is to integrate Doppler velocimetry with biophysical profiling in order to determine the optimal timing of delivery, thus reducing the risks of adverse perinatal outcomes.

  13. Utero-placental perfusion Doppler indices in growth restricted fetuses: effect of sildenafil citrate.

    Science.gov (United States)

    El-Sayed, Mohamed Adel; Saleh, Said Abdel-Aty; Maher, Mohammad Ahmed; Khidre, Asmaa Mohamed

    2018-04-01

    To assess efficacy and tolerability of sildenafil citrate on utero-placental blood flow and fetal growth in pregnancies complicated by fetal growth restriction (FGR). From March 2015, a randomized controlled trial of 54 patients at 24 weeks or more complicated by FGR and abnormal Doppler indices were randomly allocated 1:1 into an intervention arm (receive sildenafil citrate, 50 mg) or a control arm (receive placebo). The primary outcomes were changes occurred in the Doppler parameters 2 h following drug administration. Baseline characteristics were similar between groups. Significant difference was observed in the Delta uterine and umbilical Doppler indices among sildenafil group as compared to placebo group (p Doppler indices, however, decreased significantly after sildenafil, which could be the result of shifting more blood to improve the utero-placental perfusion. No difference regarding Delta cerebro-placental ratio among both groups (p = 0.979). Sildenafil was also associated with pregnancy prolongation (p = .0001), increased gestational age at delivery (p = .004), improved neonatal weight (p = .0001), and less admission to neonatal intensive care unit (p = .03). No adverse effects reported in both treatment arms. Sildenafil citrate, by its vasodilator effect, can improve utero-placental blood flow in pregnancies complicated by FGR and abnormal Doppler. gov Registry: NCT02362399.

  14. Doppler tomography in fusion plasmas and astrophysics

    DEFF Research Database (Denmark)

    Salewski, Mirko; Geiger, B.; Heidbrink, W. W.

    2015-01-01

    Doppler tomography is a well-known method in astrophysics to image the accretion flow, often in the shape of thin discs, in compact binary stars. As accretion discs rotate, all emitted line radiation is Doppler-shifted. In fast-ion Dα (FIDA) spectroscopy measurements in magnetically confined plasma......, the Dα-photons are likewise Doppler-shifted ultimately due to gyration of the fast ions. In either case, spectra of Doppler-shifted line emission are sensitive to the velocity distribution of the emitters. Astrophysical Doppler tomography has lead to images of accretion discs of binaries revealing bright...... spots, spiral structures and flow patterns. Fusion plasma Doppler tomography has led to an image of the fast-ion velocity distribution function in the tokamak ASDEX Upgrade. This image matched numerical simulations very well. Here we discuss achievements of the Doppler tomography approach, its promise...

  15. Echobiometrics kidney and renal artery triplex doppler of canine fetuses

    Directory of Open Access Journals (Sweden)

    M.A.R. Feliciano

    2014-04-01

    Full Text Available The aim of this study was to assess the sogographic parameters and biometry of canine fetal kidneys using the B mode, and to determinate the vascular index of the fetal renal arteries using the Doppler Triplex. Twenty four Shi-tzu and Pug, weighting between 4 and 10kg, aging between 4 and 6 years old were evaluated. The B mode, the fetal renal echobiometry and regularity of the renal surface, echotexture and cortex:medular ratio were evaluated during the 5th, 6th, 7th and 8th weeks of pregnancy. At the same time point of the B mode evaluation, the Doppler Triplex was carried out to assess the sistolic peak velocity (SPV, end diastolic velocity (EDV, vascular resistive (RI and pulsatility index (PI. B mode revealed no fetal renal abnormalities and echobiometry showed important measurements during fetal development (P0.05. B mode and Doppler Triplex were important tools for the assessment of fetal renal development, using echobiometry and renal arterial index in canie fetuses.

  16. Uterine arteriovenous malformations: gray-scale and Doppler US features with MR imaging correlation.

    Science.gov (United States)

    Huang, M W; Muradali, D; Thurston, W A; Burns, P N; Wilson, S R

    1998-01-01

    To describe the gray-scale and color and duplex Doppler ultrasound (US) and the magnetic resonance (MR) imaging features of uterine arteriovenous malformations (AVMs). Uterine AVMs in 10 patients were retrospectively evaluated. All patients underwent gray-scale US and color and duplex Doppler US. Nine underwent angiography with therapeutic embolization; four, MR imaging. The resistance index (RI), pulsatility index (PI), and peak systolic velocities (PSVs) were evaluated. At gray-scale US, uterine AVMs were nonspecific and manifested as subtle myometrial inhomogeneity, tubular spaces within the myometrium, intramural uterine mass, endometrial mass, or cervical mass or sometimes as prominent parametrial vessels. Color Doppler features were consistent and included intense juxtaposed signals with aliasing and apparent flow reversals. Spectral Doppler US revealed low-resistance flow (RI, 0.25-0.55; PI, 0.3-0.6) and PSVs greater than 96 cm/sec, which suggests arteriovenous shunting. MR imaging showed a bulky uterus, a focal uterine mass, disruption of the junctional zones, serpiginous flow-related signal voids, and prominent parametrial vessels. Gray-scale morphology and Doppler US features should allow noninvasive diagnosis of uterine AVMs. Doppler and MR imaging features of uterine AVMs may overlap with other causes of arteriovenous shunting, including abnormal placentation and gestational trophoblastic disease (GTD). These can be differentiated with serum beta human chorionic gonadotropin test results (negative with AVM, positive with GTD).

  17. Fetal and umbilical Doppler ultrasound in high-risk pregnancies.

    Science.gov (United States)

    Alfirevic, Zarko; Stampalija, Tamara; Dowswell, Therese

    2017-06-13

    Abnormal blood flow patterns in fetal circulation detected by Doppler ultrasound may indicate poor fetal prognosis. It is also possible that false positive Doppler ultrasound findings could lead to adverse outcomes from unnecessary interventions, including preterm delivery. The objective of this review was to assess the effects of Doppler ultrasound used to assess fetal well-being in high-risk pregnancies on obstetric care and fetal outcomes. We updated the search of Cochrane Pregnancy and Childbirth's Trials Register on 31 March 2017 and checked reference lists of retrieved studies. Randomised and quasi-randomised controlled trials of Doppler ultrasound for the investigation of umbilical and fetal vessels waveforms in high-risk pregnancies compared with no Doppler ultrasound. Cluster-randomised trials were eligible for inclusion but none were identified. Two review authors independently assessed the studies for inclusion, assessed risk of bias and carried out data extraction. Data entry was checked. We assessed the quality of evidence using the GRADE approach. Nineteen trials involving 10,667 women were included. Risk of bias in trials was difficult to assess accurately due to incomplete reporting. None of the evidence relating to our main outcomes was graded as high quality. The quality of evidence was downgraded due to missing information on trial methods, imprecision in risk estimates and heterogeneity. Eighteen of these studies compared the use of Doppler ultrasound of the umbilical artery of the unborn baby with no Doppler or with cardiotocography (CTG). One more recent trial compared Doppler examination of other fetal blood vessels (ductus venosus) with computerised CTG.The use of Doppler ultrasound of the umbilical artery in high-risk pregnancy was associated with fewer perinatal deaths (risk ratio (RR) 0.71, 95% confidence interval (CI) 0.52 to 0.98, 16 studies, 10,225 babies, 1.2% versus 1.7 %, number needed to treat (NNT) = 203; 95% CI 103 to 4352

  18. Low-frequency high-definition power Doppler in visualizing and defining fetal pulmonary venous connections.

    Science.gov (United States)

    Liu, Lin; He, Yihua; Li, Zhian; Gu, Xiaoyan; Zhang, Ye; Zhang, Lianzhong

    2014-07-01

    The use of low-frequency high-definition power Doppler in assessing and defining pulmonary venous connections was investigated. Study A included 260 fetuses at gestational ages ranging from 18 to 36 weeks. Pulmonary veins were assessed by performing two-dimensional B-mode imaging, color Doppler flow imaging (CDFI), and low-frequency high-definition power Doppler. A score of 1 was assigned if one pulmonary vein was visualized, 2 if two pulmonary veins were visualized, 3 if three pulmonary veins were visualized, and 4 if four pulmonary veins were visualized. The detection rate between Exam-1 and Exam-2 (intra-observer variability) and between Exam-1 and Exam-3 (inter-observer variability) was compared. In study B, five cases with abnormal pulmonary venous connection were diagnosed and compared to their anatomical examination. In study A, there was a significant difference between CDFI and low-frequency high-definition power Doppler for the four pulmonary veins observed (P definition power Doppler was higher than that when employing two-dimensional B-mode imaging or CDFI. There was no significant difference between the intra- and inter-observer variabilities using low-frequency high-definition power Doppler display of pulmonary veins (P > 0.05). The coefficient correlation between Exam-1 and Exam-2 was 0.844, and the coefficient correlation between Exam-1 and Exam-3 was 0.821. In study B, one case of total anomalous pulmonary venous return and four cases of partial anomalous pulmonary venous return were diagnosed by low-frequency high-definition power Doppler and confirmed by autopsy. The assessment of pulmonary venous connections by low-frequency high-definition power Doppler is advantageous. Pulmonary venous anatomy can and should be monitored during fetal heart examination.

  19. Gastro-enteritis in huisartsenpeilstations.

    NARCIS (Netherlands)

    Wit, M.A.S. de; Koopmans, M.P.G.; Kortbeek, L.M.; Leeuwen, W.J. van; Vinje, J.; Bartelds, A.I.M.; Duijnhoven, Y.T.P.H. van

    1998-01-01

    De incidentie van huisartsconsulten voor gastro-enteritis van 77 per 10.000 persoonjaren lijkt een lichte daling te vertonen t.o.v. de incidentie van 90 per 10.000 persoonjaren in een vergelijkbaar onderzoek in 1992-1993. De belangrijkste verwekkers van gastro-enteritis waarvoor de huisarts wordt

  20. General principles of carotid Doppler ultrasonography

    Directory of Open Access Journals (Sweden)

    Whal Lee

    2014-01-01

    Full Text Available

    Carotid Doppler ultrasonography is a popular tool for evaluating atherosclerosis of the carotid artery. Its two-dimensional gray scale can be used for measuring the intima-media thickness, which is very good biomarker for atherosclerosis and can aid in plaque characterization. The plaque morphology is related to the risk of stroke. The ulceration of plaque is also known as one of the strong predictors of future embolic event risk. Color Doppler ultrasonography and pulse Doppler ultrasonography have been used for detecting carotid artery stenosis. Doppler ultrasonography has unique physical properties. The operator should be familiar with the physics and other parameters of Doppler ultrasonography to perform optimal Doppler ultrasonography studies.

  1. Doppler effects on periodicities in Saturn's magnetosphere

    Science.gov (United States)

    Carbary, J. F.

    2015-11-01

    The magnetosphere of Saturn exhibits a wide variety of periodic phenomena in magnetic fields, charged particles, and radio emissions. The periodicities are observed from a moving spacecraft, so an issue arises about the periodicities being influenced by the Doppler effects. Doppler effects can be investigated using models of the periodicities and then flying the spacecraft through the model, effectively measuring any Doppler phenomena with the simulation. Using 200 days of typical elliptical orbits from the Cassini mission at Saturn, three models were tested: an azimuthal wave (or "searchlight") model, a radial wave (or "pond ripple") model, and a model of an outwardly traveling spiral wave. The azimuthal wave model produced virtually no Doppler effects in the periodicities because its wave vector is nearly perpendicular to the spacecraft trajectory. The radial wave model generated strong Doppler effects of an upshifted and a downshifted signal (a dual period) on either side of the true period, because the wave vector is either parallel or antiparallel to the spacecraft trajectory. Being intermediate to the searchlight and radial waves, the spiral wave produced Doppler effects but only for low wave speeds (<10 RS/h). For higher wave speeds the Doppler effects were not as clear. The Doppler effects can be mitigated by employing only observations beyond ~15 RS where the spacecraft speed is low compared to the wave speed. The observed periodicities over the same 200 day interval do not show evidence of Doppler effects but generally display a single feature at the expected ~10.7 h period.

  2. Structurally abnormal human autosomes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-12-31

    Chapter 25, discusses structurally abnormal human autosomes. This discussion includes: structurally abnormal chromosomes, chromosomal polymorphisms, pericentric inversions, paracentric inversions, deletions or partial monosomies, cri du chat (cat cry) syndrome, ring chromosomes, insertions, duplication or pure partial trisomy and mosaicism. 71 refs., 8 figs.

  3. Doppler Monte Carlo simulations of light scattering in tissue to support laser-Doppler perfusion measurements

    NARCIS (Netherlands)

    de Mul, F.F.M.; Steenbergen, Wiendelt; Greve, Jan

    1999-01-01

    Doppler Monte Carlo (DMC) simulations of the transport of light through turbid media, e.g., tissue, can be used to predict or to interpret measurements of the blood perfusion of tissue by laser‐Doppler perfusion flowmetry. We describe the physical and mathematical background of Doppler Monte Carlo

  4. Technical aspects of enteral nutrition.

    OpenAIRE

    Keymling, M

    1994-01-01

    Advances in technical aspects of enteral feeding such as the manufacture of tubes from polyurethane or silicone have helped promote the science of enteral nutrition. Nasoenteral tubes have few complications, apart from a high unwanted extubation rate and some reluctance from patients because of cosmetic unacceptability. Needle jejunostomy has low morbidity but can only be placed at laparotomy. Percutaneous gastrotomy (in all its different guises) has been established as a low risk procedure a...

  5. Recent Advances in Enteral Nutrition

    OpenAIRE

    Ojo, Omorogieva; Brooke, Joanne

    2016-01-01

    There have been significant advances in the provision of enteral nutrition support in the acute and community healthcare settings. Enteral nutrition is beneficial to individuals who have functional guts but may not be able to meet their nutritional requirements via a normal diet. Most of these people have neurological conditions such as stroke, multiple sclerosis and dementia which could impact on swallowing reflexes, leading to dysphagia [1]. Others may have cancer, intellectual disability o...

  6. EARLY ENTERAL FEEDING AND DELAYED ENTERAL FEEDING- A COMPARATIVE STUDY

    Directory of Open Access Journals (Sweden)

    Alli Muthiah

    2017-03-01

    Full Text Available BACKGROUND Nutrients form the fuel for the body, which comes in the form of carbohydrates, proteins and lipids. The body is intended to burn fuels in order to perform work. Starvation with malnutrition affects the postoperative patients and patients with acute pancreatitis. There is an increased risk of nosocomial infections and a delay in the wound healing may be noted. They are more prone for respiratory tract infections. Enteral Nutrition (EN delivers nutrition to the body through gastrointestinal tract. This also includes the oral feeding. This study will review the administration, rationale and assess the pros and cons associated with the early initiation of enteral feeding. The aim of this study is to evaluate if early commencement of enteral nutrition compared to traditional management (delayed enteral feeding is associated with fewer complications and improved outcome-  In patients undergoing elective/emergency gastrointestinal surgery.  In patients with acute pancreatitis. It is also used to determine whether a period of starvation (nil by mouth after gastrointestinal surgery or in the early days of acute pancreatitis is beneficial in terms of specific outcomes. MATERIALS AND METHODS A prospective cohort interventional study was conducted using 100 patients from July 2012 to November 2012. Patients satisfying the inclusion and exclusion criteria were included in the study. Patients admitted in my unit for GIT surgeries or acute pancreatitis constituted the test group, while patients admitted in other units for similar disease processes constituted the control group. RESULTS Our study concluded that early enteral feeding resulted in reduced incidence of surgical site infections. When the decreased length of stay, shorter convalescent period and the lesser post-interventional fatigue were taken into account, early enteral feeding has a definite cost benefit.CONCLUSION Early enteral feeding was beneficial associated with fewer

  7. [Prenatal diagnosis of single umbilical artery: implications for chromosomal abnormalities and neonatal outcome].

    Science.gov (United States)

    Chang, Qingxian; Chen, Cuihua; Zhong, Mei; Qiu, Yuwen; Xiao, Chaoqun; Huang, Qitao; Yu, Yanhong

    2013-03-01

    To investigate the implications of a prenatal diagnosis of single umbilical artery (SUA) for chromosomal abnormalities and neonatal outcomes. From January, 2008 to June, 2012, color Doppler ultrasound identified 44 fetuses with SUA. Prenatal diagnoses with amniocentesis or umbilical blood sampling were subsequently ordered for routine chromosome karyotyping and the newborns were followed up for assessing the neonatal outcomes. Of all the 44 fetuses, 24 had uncomplicated SUA, and 20 had other concurrent abnormalities (including 8 with abnormal ultrasound soft indexes and 12 with chromosomal abnormalities). The two groups of fetuses showed significant differences in gestational weeks at delivery and incidence of chromosomal abnormalities but not in neonatal weight, placenta weight or APGAR score. Fetuses with a prenatal diagnosis of SUA and other development abnormities need to undergo prenatal chromosomal examination. For fetuses with uncomplicated SUA, careful ultrasound examination is necessary to avoid missed diagnosis of potential congenital abnormalities.

  8. Frequency of mitral valve dysfunction from mitral anular calcium as detected by Doppler echocardiography.

    Science.gov (United States)

    Labovitz, A J; Nelson, J G; Windhorst, D M; Kennedy, H L; Williams, G A

    1985-01-01

    Doppler echocardiography is useful for detecting and quantifying mitral regurgitation (MR) and mitral stenosis (MS). To determine the prevalence of these abnormalities in patients with mitral anular calcium (MAC), 51 consecutive patients who had an echocardiographic diagnosis of MAC were examined by Doppler ultrasound. Transmitral flow was evaluated to determine the presence of MR or left ventricular inflow obstruction (MS) by continuous and pulsed-wave Doppler echocardiography. The severity of these hemodynamic abnormalities was quantitated by previously described techniques. Eleven patients (22%) had mild MR, 17 (33%) had moderate to severe MR and 4 (8%) had significant MS. Clinical findings such as a systolic murmur, evidence of congestive heart failure, and dyspnea on exertion were not helpful in distinguishing patients with no or mild MR from those who had moderate to severe MR. M-mode measured left atrial size was significantly larger (p less than 0.05) in patients with moderate to severe MR. This study suggests that MR is often associated with MAC, that MS is not a rare finding with MAC, and that Doppler echocardiography can quantitate these lesions in the elderly when symptoms are not specific and physical findings are inconclusive or absent.

  9. Selective IUGR in dichorionic twins: what can Doppler assessment and growth discordancy say about neonatal outcomes?

    Science.gov (United States)

    Algeri, Paola; Frigerio, Matteo; Lamanna, Maria; Petrova, Petya Vitanova; Cozzolino, Sabrina; Incerti, Maddalena; Mastrolia, Salvatore Andrea; Roncaglia, Nadia; Vergani, Patrizia

    2017-12-29

    The aim of the present study was to assess, in a population of dichorionic twin pregnancies with selective growth restriction, the effect of inter-twin differences by use of Doppler velocimetry and fetal growth discordancy on perinatal outcomes. This was a retrospective study including dichorionic twin pregnancies from January 2008 to December 2015 at the Department of Obstetrics and Gynecology of Fondazione MBBM. Only dichorionic twin pregnancies affected by selective intrauterine growth restriction (IUGR) delivering at ≥24 weeks were included in the study. We found that twin pregnancies with inter-twin estimated fetal weight (EFW) discordance ≥15% were significantly associated with a higher risk of preterm delivery before 32 (P=0.004) and 34 weeks (P=0.04). Similarly, twin pregnancies with inter-twin abdominal circumference (AC) discordance ≥30° centiles were associated with a higher rate of neonatal intensive care unit (NICU) admission (P=0.02), neonatal resuscitation (P=0.02) and adverse neonatal composite outcome (P=0.04). Of interest, when comparing twin pregnancies according to Doppler study, growth restricted twins had a higher rate of composite neonatal outcome and in multivariate analysis, an abnormal Doppler was an independent risk factor for this outcome. Our study associated growth discrepancy with specific pregnancy outcomes, according to defined cut-offs. In addition, we demonstrated that an abnormal umbilical artery Doppler is independently associated with a composite neonatal adverse outcome in growth restricted fetuses.

  10. Estimating effect of terlipressin on portal pressure in cirrhosis by observing hepatic vein Doppler waveform.

    Science.gov (United States)

    Hussain, Qurban; Haider, Shahbaz; Solangi, Noor Muhammad; Ali, Liaquat; Liaquat, Hammad; Ahmed, Fayyaz; Shahbaz, Sumera

    2013-05-01

    To observe the changes in Doppler waveform of hepatic vein after the administration of terlipressin, and to assess indirectly the efficacy of the drug to reduce the Hepatic Vein Pressure Gradient and portal pressure. The quasi-experimental study was conducted at the Jinnah Postgraduate Medical Centre, Karachi, from April 1 to November 25, 2011, and comprised 50 patients with cirrhosis with abnormal Doppler waveform of the hepatic vein. Patients with diseases causing abnormal hepatic vein doppler waveform were excluded. Doppler waveforms were studied for 20 minutes before and for 20 minutes after the administration of terlipressin. Tracings with best waveform before and after injection were saved for analysis. Changes in waveform after vasoactive drug were defined as mild, significant, marked and gross changes. SPSS 10 was used for statistical analysis. Of the 50 patients, 36 (72%) were males and 14 (28%) females. Commonest waveform was monophasic 38 (76%). Gross changes i.e. turning triphasic from monophasic waveform was observed in 8 (16%) patients. Significant gross changes were seen in 24 (48%) patients. Total number of patients showing improvement in waveform was 36 (72%). In no case, waveform deteriorated after the administration of terlipressin (p = 0.001). Non-invasive method of observing the improvement of hepatic vein waveform by duplex ultrasound, after more studies, may be an important tool for assessing and monitoring the effects of portal pressure lowering drugs.

  11. Doppler broadening effects in plasmonic quantum dots

    Science.gov (United States)

    Alves, R. A.; Silva, Nuno A.; Costa, J. C.; Gomes, M.; Guerreiro, A.

    2017-08-01

    In this paper we analyse the effects of the Doppler shift on the optical response of a nanoplasmonic system. Through the development of a simplified model based on the Hydrodynamic Drude model we analyse the response of a quantum dot embed in a moving fluid, predicting the Doppler broadening and the shift of the spectral line.

  12. Radar Doppler Processing with Nonuniform Sampling.

    Energy Technology Data Exchange (ETDEWEB)

    Doerry, Armin W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-07-01

    Conventional signal processing to estimate radar Doppler frequency often assumes uniform pulse/sample spacing. This is for the convenience of t he processing. More recent performance enhancements in processor capability allow optimally processing nonuniform pulse/sample spacing, thereby overcoming some of the baggage that attends uniform sampling, such as Doppler ambiguity and SNR losses due to sidelobe control measures.

  13. [Color echo-doppler of the ureterovesical stream. Normal aspects. Application to the acute ureteral obstruction].

    Science.gov (United States)

    Thomas, E; Menu, Y; Servois, V; Hercot, O; Boccon-Gibod, L; Laissy, J P

    1993-02-01

    A colour Doppler ultrasound study of the ureterovesical was performed to define the normal features, variants and abnormalities of the ureteric stream by comparing 50 normal subjects and 19 subjects with renal colic due to ureteric stones. The examination included assessment of the frequency, intensity, morphology and symmetry of the ureterovesical stream. In normal subjects, the stream was either absent, especially in the case of fluid restriction (36%), present and symmetrical (34%) or asymmetrical (30%). In patients with ureteric stones, during a non-painful period and in the absence of obstruction on IVU, the stream was normal and symmetrical (9%) while during a painful period with obstruction on IVU, the ureteric stream was either absent (47%) or abnormal and asymmetrical (31%). A continuous stream, very suggestive of obstruction, was observed in 5 cases. Colour Doppler ultrasound is a new, simple method which may be helpful in the diagnosis of renal colic, particularly in cases in which the pyelocaliceal cavities are not dilated.

  14. Development and Application of integrated monitoring platform for the Doppler Weather SA-BAND Radar

    Science.gov (United States)

    Zhang, Q.; Sun, J.; Zhao, C. C.; Chen, H. Y.

    2017-10-01

    The doppler weather SA-band radar is an important part of modern meteorological observation methods, monitoring the running status of radar and the data transmission is important.This paper introduced the composition of radar system and classification of radar data,analysed the characteristics and laws of the radar when is normal or abnormal. Using Macromedia Dreamweaver and PHP, developed the integrated monitoring platform for the doppler weather SA-band radar which could monitor the real-time radar system running status and important performance indicators such as radar power,status parameters and others on Web page,and when the status is abnormal it will trigger the audio alarm.

  15. Systemic lupus erythematosus presenting with eosinophilic enteritis: a case report

    Directory of Open Access Journals (Sweden)

    Kalany Mohammad

    2011-06-01

    Full Text Available Abstract Introduction Systemic lupus erythematosus (SLE is a multisystem disorder that may present with various symptoms. It may involve the gastrointestinal tract in a variety of ways; some of the most well-known ones are transaminitis, lupus mesenteric vasculitis, lupus enteritis and mesenteric vascular leakage. We describe a case of a patient with SLE who presented with a five-month history of diarrhea caused by eosinophilic enteritis. To the best of our knowledge, there are few cases reported in the literature of patients with SLE who initially present with chronic diarrhea due to eosinophilic enteritis. Case presentation A 38-year-old Persian Iranian woman was admitted with a five-month history of diarrhea and abdominal pain. A physical examination showed nothing abnormal. Initially, she had only lymphopenia and mild eosinophilia. No autoimmune or infectious etiology was detected to justify these abnormalities. A thorough evaluation was not helpful in finding the etiology, until she developed a scalp lesion similar to discoid lupus erythematosus. Computed tomography showed small bowel wall thickening. Briefly, she manifested full-blown SLE, and it was revealed that the diarrhea was caused by eosinophilic enteritis. Conclusion Considering SLE in a patient who presents with chronic diarrhea and lymphopenia may be helpful in earlier diagnosis and therapy. This is an original case report of interest to physicians who practice internal medicine, family medicine and gastroenterology.

  16. Aortic isthmus Doppler velocimetry: role in assessment of preterm fetal growth restriction.

    LENUS (Irish Health Repository)

    Kennelly, M M

    2012-02-01

    Intrauterine fetal growth restriction (IUGR) is an important pregnancy complication associated with significant adverse clinical outcome, stillbirth, perinatal morbidity and cerebral palsy. To date, no uniformly accepted management protocol of Doppler surveillance that reduces mortality and cognitive morbidity has emerged. Aortic isthmus (AoI) evaluation has been proposed as a potential monitoring tool for IUGR fetuses. In this review, the current knowledge of the relationship between AoI Doppler velocimetry and preterm fetal growth restriction is reviewed. Relevant technical aspects and reproducibility data are reviewed as we discuss AoI Doppler and its place within the existing repertoire of Doppler assessments in placental insufficiency. The AoI is a link between the right and left ventricles which perfuse the lower and upper body, respectively. The clinical use of AoI waveforms for monitoring fetal deterioration in IUGR has been limited, but preliminary work suggests that abnormal AoI impedance indices are an intermediate step between placental insufficiency-hypoxemia and cardiac decompensation. Further prospective studies correlating AoI indices with arterial and venous Doppler indices and perinatal outcome are required before encorporating this index into clinical practice.

  17. Estimating the Doppler centroid of SAR data

    DEFF Research Database (Denmark)

    Madsen, Søren Nørvang

    1989-01-01

    After reviewing frequency-domain techniques for estimating the Doppler centroid of synthetic-aperture radar (SAR) data, the author describes a time-domain method and highlights its advantages. In particular, a nonlinear time-domain algorithm called the sign-Doppler estimator (SDE) is shown to have...... attractive properties. An evaluation based on an existing SEASAT processor is reported. The time-domain algorithms are shown to be extremely efficient with respect to requirements on calculations and memory, and hence they are well suited to real-time systems where the Doppler estimation is based on raw SAR...... data. For offline processors where the Doppler estimation is performed on processed data, which removes the problem of partial coverage of bright targets, the ΔE estimator and the CDE (correlation Doppler estimator) algorithm give similar performance. However, for nonhomogeneous scenes it is found...

  18. Observation of the Zero Doppler Effect.

    Science.gov (United States)

    Ran, Jia; Zhang, Yewen; Chen, Xiaodong; Fang, Kai; Zhao, Junfei; Chen, Hong

    2016-04-05

    The normal Doppler effect has well-established applications in many areas of science and technology. Recently, a few experimental demonstrations of the inverse Doppler effect have begun to appear in negative-index metamaterials. Here we report an experimental observation of the zero Doppler effect, that is, no frequency shift irrespective of the relative motion between the wave signal source and the detector in a zero-index metamaterial. This unique phenomenon, accompanied by the normal and inverse Doppler effects, is generated by reflecting a wave from a moving discontinuity in a composite right/left-handed transmission line loaded with varactors when operating in the near zero-index passband, or the right/left-handed passband. This work has revealed a complete picture of the Doppler effect in metamaterials and may lead to potential applications in electromagnetic wave related metrology.

  19. Size distribution of air bubbles entering the brain during cardiac surgery.

    Directory of Open Access Journals (Sweden)

    Emma M L Chung

    Full Text Available Thousands of air bubbles enter the cerebral circulation during cardiac surgery, but whether high numbers of bubbles explain post-operative cognitive decline is currently controversial. This study estimates the size distribution of air bubbles and volume of air entering the cerebral arteries intra-operatively based on analysis of transcranial Doppler ultrasound data.Transcranial Doppler ultrasound recordings from ten patients undergoing heart surgery were analysed for the presence of embolic signals. The backscattered intensity of each embolic signal was modelled based on ultrasound scattering theory to provide an estimate of bubble diameter. The impact of showers of bubbles on cerebral blood-flow was then investigated using patient-specific Monte-Carlo simulations to model the accumulation and clearance of bubbles within a model vasculature.Analysis of Doppler ultrasound recordings revealed a minimum of 371 and maximum of 6476 bubbles entering the middle cerebral artery territories during surgery. This was estimated to correspond to a total volume of air ranging between 0.003 and 0.12 mL. Based on analysis of a total of 18667 embolic signals, the median diameter of bubbles entering the cerebral arteries was 33 μm (IQR: 18 to 69 μm. Although bubble diameters ranged from ~5 μm to 3.5 mm, the majority (85% were less than 100 μm. Numerous small bubbles detected during cardiopulmonary bypass were estimated by Monte-Carlo simulation to be benign. However, during weaning from bypass, showers containing large macro-bubbles were observed, which were estimated to transiently affect up to 2.2% of arterioles.Detailed analysis of Doppler ultrasound data can be used to provide an estimate of bubble diameter, total volume of air, and the likely impact of embolic showers on cerebral blood flow. Although bubbles are alarmingly numerous during surgery, our simulations suggest that the majority of bubbles are too small to be harmful.

  20. Chromosomal Abnormalities in ADHD

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2002-07-01

    Full Text Available The prevalence of fragile X syndrome, velocardiofacial syndrome (VCFS, and other cytogenetic abnormalities among 100 children (64 boys with combined type ADHD and normal intelligence was assessed at the NIMH and Georgetown University Medical Center.

  1. Chromosomal abnormalities and autism

    Directory of Open Access Journals (Sweden)

    Farida El-Baz

    2016-01-01

    Conclusion: Chromosomal abnormalities were not detected in the studied autistic children, and so the relation between the genetics and autism still needs further work up with different study methods and techniques.

  2. Simultaneous recording of pulsed wave Doppler signals in the innominate vein and transverse aortic arch: a new technique to evaluate AV conduction and fetal heart rhythm.

    Science.gov (United States)

    Howley, Lisa W; Schuchardt, Eleanor; Park, Dawn; Gilbert, Lisa; Gruenwald, Jeanine; Cuneo, Bettina F

    2018-02-02

    Fetal heart rhythm abnormalities are common. Simultaneous pulsed Doppler interrogation of the superior vena cava (SVC) and ascending aorta (AAo) is widely used to analyze fetal arrhythmias. However, the SVC/AAo Doppler technique can be limited by a suboptimal angle of interrogation and poor visualization of atrial systole in the SVC. We present our experience with a novel Doppler technique using simultaneously recorded pulsed wave Doppler signals in the innominate vein (InnV) and transverse aortic arch (Ao) from an axial view of the fetal thorax. Advantages of the InnV/Ao Doppler technique include improved acquisition feasibility and a near 0-degree angle of insonation of the InnV, improving visualization of atrial systolic events. This article is protected by copyright. All rights reserved.

  3. Sonographic Characteristics of Extensor Tendon Abnormalities and Relationship With Joint Disease Activity in Rheumatoid Arthritis: A Pilot Study.

    Science.gov (United States)

    Ramrattan, Laurie Ann; Kaeley, Gurjit Singh

    2017-05-01

    To characterize abnormalities in the dorsal extensor tendons of the hand and determine the importance of these findings in rheumatoid arthritis. A retrospective cross-sectional study was done on 26 patients with rheumatoid arthritis who had sonography of their hands. B-mode and power Doppler joint activity were scored, and the extensor tendons were examined for B-mode changes and power Doppler signals. B-mode changes included anechoic fluid around tendons, hypoechoic tissue around tendons, paratendon tissue and tendon thickening, as well as vascularity around the tendon, for which peritendon power Doppler signals were recorded. Forty-one hands and 205 joints were reviewed. Anechoic fluid around the tendons and peritendon power Doppler signals were observed in 41% and 39%, respectively; 44% and 28% of patients had B-mode and power Doppler scores in the upper tertile, respectively. For both B-mode and power Doppler scores, 3 categories or tertiles were created, 0 to 0.9, 1 to 1.9, and 2 to 3. We reported the percentage of patients with power Doppler and B-mode scores in this category. The severity of synovitis was associated with anechoic fluid around the tendons and peritendon power Doppler signals according to the Cochran-Mantel-Haenszel test. The common odds ratio was 3.52 (95% confidence interval, 1.45- 8.53) for anechoic fluid around the tendons and severe synovitis. The common odds ratio was 2.52 (95% confidence interval, 1.13-5.63) for peritendon power Doppler signals and severe synovitis. Findings at the dorsal extensor tendons were anechoic fluid around tendons, hypoechoic tissue around tendons, peritendon power Doppler signals, and tendon thickening. Patients with anechoic fluid and power Doppler signals were found to have more severe disease activity at the joints based on B-mode and power Doppler scores. © 2017 by the American Institute of Ultrasound in Medicine.

  4. Ultrasonographic investigation of the Achilles tendon in elite badminton players using color Doppler.

    Science.gov (United States)

    Boesen, Morten Ilum; Boesen, Anders; Koenig, Merete Juhl; Bliddal, Henning; Torp-Pedersen, Soren

    2006-12-01

    The most frequent injuries in badminton players are in the lower extremities, especially in the Achilles tendon. The game of badminton may be related to abnormal intratendinous flow in the Achilles tendon as detected by color Doppler ultrasound. To a certain extent, this blood flow might be physiological, especially when examined after match. Cohort study (prevalence); Level of evidence, 3. Seventy-two elite badminton players were interviewed regarding Achilles tendon pain (achillodynia) in the preceding 3 years. Color Doppler was used to examine the tendons of 64 players before their matches and 46 players after their matches. Intratendinous color Doppler flow was graded from 0 to 4. The Achilles tendon was divided into dominant (eg, right side for right-handed players and vice versa) and nondominant side and classified as midtendon, preinsertional, and calcaneal areas. Of 72 players, 26 had experienced achillodynia in 34 tendons, 18 on the dominant side and 16 on the nondominant side. In 62% of the players with achillodynia, the problems had begun slowly, and the median duration of symptoms was 4 months (range, 0-36 months). Thirty-five percent had ongoing pain in their tendons for a median duration of 12 months (range, 0-12 months). Achillodynia was not associated with the self-reported training load or with sex, age, weight, singles or doubles players, or racket side. Forty-six players were scanned before and after match. At baseline, color Doppler flow was present in the majority of players, and only 7 (16%) players had no color Doppler flow in either tendon. After match, all players had some color Doppler flow in 1 or both tendons. Achillodynia and color Doppler flow were related in the nondominant Achilles tendon (chi-square, P = .008). The grades of Doppler flow also increased significantly after match in the preinsertional area in both the nondominant (P = .0002) and dominant (P = .005) side tendons. A large proportion of the players had experienced

  5. Meat-based enteral nutrition

    Science.gov (United States)

    Derevitskay, O. K.; Dydykin, A. S.

    2017-09-01

    Enteral nutrition is widely used in hospitals as a means of nutritional support and therapy for different diseases. Enteral nutrition must fulfil the energy needs of the body, be balanced by the nutrient composition and meet patient’s nutritional needs. Meat is a source of full-value animal protein, vitamins and minerals. On the basis of this research, recipes and technology for a meat-based enteral nutrition product were developed. The product is a ready-to-eat sterilised mixture in the form of a liquid homogeneous mass, which is of full value in terms of composition and enriched with vitamins and minerals, consists of particles with a size of not more than 0.3 mm and has the modified fat composition and rheological characteristics that are necessary for passage through enteral feeding tubes. The study presents experimental data on the content of the main macro- and micro-nutrients in the developed product. The new product is characterised by a balanced fatty acid composition, which plays an important role in correction of lipid metabolism disorders and protein-energy deficiency, and it is capable of satisfying patients’ daily requirements for vitamins and the main macro- and microelements when consuming 1500-2000 ml. Meat-based enteral nutrition can be used in diets as a standard mixture for effective correction of the energy and anabolic requirements of the body and support of the nutritional status of patients, including those with operated stomach syndrome.

  6. Laser Doppler velocity measurements of swirling flows with upstream influence

    Science.gov (United States)

    Rloff, K. L.; Bossel, H. H.

    1973-01-01

    Swirling flow in a rotating tube is studied by flow visualization at a moderate Reynolds number, and its velocity field is measured by laser-Doppler anemometry. The tube has constant diameter, and approximately uniform initial rigid rotation of the flow is assured by passing the flow through a rotating plug of porous metal before it enters the test section. At moderate swirl values, an object mounted on the tube centerline causes a closed bubble to form upstream of the obstacle, with a clearly defined stagnation point on the axis, and recirculating flow inside the bubble. The bubble length grows upstream as the swirl is increased, until it breaks up into a Taylor column reaching all the way upstream and downstream at swirl values above a certain critical value. A vortex jump (in the sense of Benjamin) occurs downstream of the obstacle except when the Taylor column is present. Using a laser-Doppler anemometer, axial and swirl velocity profiles are obtained at several stations upstream and downstream of the bubble, and in and around the bubble.

  7. Doppler weather radar as a meteorite recovery tool

    Science.gov (United States)

    Fries, Marc; Fries, Jeffrey

    2010-09-01

    We report the use of Doppler weather radar as a tool for locating meteorites, both at the time of a fall and from archived radar data. This asset is especially useful for meteorite recovery as it can provide information on the whereabouts of falling meteorites in "dark flight" portion of their descent where information on their flight paths cannot be discerned from more traditional meteorite location techniques such as eyewitness accounts. Weather radar data can provide information from detection in three distinct regimes: (A) direct detection of the rapidly moving, optically bright fireball by distant radars, (B) detection of falling debris to include hand-sample sized rocks, and (C) detection of dust produced by detonation events that can occur tens of minutes and many kilometers laterally removed from the actual fireball locality. We present examples of each, as well as comparisons against man-made debris from a re-entering Soyuz rocket and the Stardust Sample Return Capsule. The use of Doppler weather radar as a supplement to traditional meteorite recovery methods holds the promise of improving both the speed and total number of meteorite recoveries, thereby increasing the number of freshly fallen meteorites for scientific study.

  8. Enteric Neurobiology: Discoveries and Directions.

    Science.gov (United States)

    Wood, Jackie D

    Discovery and documentation of noncholinergic-nonadrenergic neurotransmission in the enteric nervous system started a revolution in mechanisms of neural control of the digestive tract that continues into a twenty-first century era of translational gastroenterology, which is now firmly embedded in the term, neurogastroenterology. This chapter, on Enteric Neurobiology: Discoveries and Directions, tracks the step-by-step advances in enteric neuronal electrophysiology and synaptic behavior and progresses to the higher order functions of central pattern generators, hard wired synaptic circuits and libraries of neural programs in the brain-in-the-gut that underlie the several different patterns of motility and secretory behaviors that occur in the specialized, serially-connected compartments extending from the esophagus to the anus.

  9. Resolving MRI abnormalities with progression of subacute sclerosing panencephalitis

    Energy Technology Data Exchange (ETDEWEB)

    Winer, J.B. (Saint Mary' s Hospital, Birmingham (UK)); Pires, M.; Kermode, A.; Ginsberg, L. (National Hospital for Nervous Diseases, Birmingham (UK)); Rossor, M. (Saint Mary' s Hospital, Birmingham (UK) National Hospital for Nervous Diseases, Birmingham (UK))

    1991-04-01

    Serial MRI was performed on a 15 year old girl with Subacute Sclerosing Pan-encephalitis (SSPE). After a period of remission she entered a phase of progressive deterioration. A repeat MRI showed significant resolution of the previous abnormalities. Her pathology and MRI scans are discussed.

  10. The role of hepatic arterial Doppler ultrasound after liver transplantation: an 'audit cycle' evaluation

    Energy Technology Data Exchange (ETDEWEB)

    MacEneaney, P.M.; Malone, D.E.; Skehan, S.J.; Curry, M.P.; Miller, J.C.; Gibney, R.G.; Traynor, O.; McCormick, P.A

    2000-07-01

    AIMS: To compare the diagnostic performance of hepatic arterial (HA) Doppler ultrasound post-liver transplantation for hepatic artery thrombosis and stenosis in our unit with the literature. To evaluate the role of the technique in clinical practice. MATERIALS AND METHODS: In a two-phase 'audit cycle' study, adult OLT patients had Doppler studies comprising detection of HA flow and measurements of peak systolic velocity, resistive index and systolic acceleration time. In phase I, patients had Doppler examinations 'routinely' and for any hepatic biochemical abnormality. In phase II, Doppler ultrasound was performed early post-OLT and later only if a senior transplant clinician suspected graft ischaemia. In addition to HA measurements the waveform was visually assessed. Clinical outcome was the 'gold standard'. RESULTS: Phase 1: 38 patients, 40 OLT operations, 125 Doppler studies; 14 arteriograms. Phase 2: 35 patients, 42 OLT operations, two HA angioplasties, one HA revision, one non-occlusive thrombus, 140 studies; 17 arteriograms. Results; Phase 1 [Phase 2]: sensitivity 80% [100%]; specificity 71% [81%]; PPV 28% [56%]; NPV 96% [100%]; incidence of HA abnormality 12.5% [19.5%]; likelihood ratio of negative result 0.28 [0]; of positive result 2.8 [5.3]. CONCLUSION: Previously reported results are reproducible. Normal HA waveform should also be a criterion of normality. The technique is very sensitive but relatively non-specific. Predictive values improve with discriminate use. MacEneaney, P. M. (2000)

  11. Effects of aspirin on adverse pregnancy outcome in patients with abnormal aneuploidy screening biochemistry tests: A randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Fatemeh Mirzaei

    2016-09-01

    Full Text Available Subject: The aim of this research is to study the effects of low dose aspirin on preventing any adverse pregnancy outcome in women with aneuploidy abnormal screening tests in second quarter and to compare the effects of aspirin on normal and abnormal Doppler.Method: This clinical trial study was performed on pregnant women with abnormal aneuploidy screening tests and normal Karyotype at the gestational age 15-18 week. It consists of 83 persons in aspirin receiving group and 84 persons in control group. Doppler ultrasound was simultaneously done on them to survey the Doppler results. Any adverse pregnancy outcome (APO was compared between two groups.Results: The frequency of APO was 32.8% in aspirin receiving group and 41.7% in control group (p=o.o14, RR=0.438. The frequency of preterm delivery before 37th week in the group receiving aspirin with normal Doppler was 8.07% and in the control group was 32.7% (P=0.025. The frequency of NICU reception with normal Doppler was 5.8% in aspirin group and 19.7% in control group (p=0.015. APO frequency in the group with many abnormal factors was 11.5% in the group receiving aspirin and 53.8% in control group (p=0.015. APO frequency in abnormal Doppler group was 46.7% in the group receiving aspirin and 50% in control group (p=0.849, RR=0.112.Conclusion: Low dose of aspirin reduces APO. It reduces preterm delivery and reference of pregnant women to NICU with abnormal aneuploidy screening tests.

  12. Nutrición enteral

    OpenAIRE

    Barrachina Bellés, Lidón; García Hernández, Misericordia; Oto Cavero, Isabel

    1984-01-01

    Este trabajo nos introduce en la administración de la nutrición enteral, haciendo una revisión de los aspectos a tener en cuenta tanto en sus indicaciones, vias, tipos, métodos, cuidados y complicaciones más importantes.

  13. Enteral Tube Feeding and Pneumonia

    Science.gov (United States)

    Gray, David Sheridan; Kimmel, David

    2006-01-01

    To determine the effects of enteral tube feeding on the incidence of pneumonia, we performed a retrospective review of all clients at our institution who had gastrostomy or jejunostomy tubes placed over a 10-year period. Ninety-three subjects had a history of pneumonia before feeding tube insertion. Eighty had gastrostomy and 13, jejunostomy…

  14. Effect of food intake on commonly used pulsed Doppler and tissue Doppler measurements.

    Science.gov (United States)

    Dencker, Magnus; Björgell, Ola; Hlebowicz, Joanna

    2011-09-01

    This study evaluates the effect of food intake on commonly used pulsed Doppler and tissue Doppler measurements. Twenty-three healthy subjects aged 25.6 ± 4.5 years were investigated. A wide selection of pulsed Doppler and tissue Doppler variables were measured before a standardized meal as well as and 30 and 110 minutes afterwards. The following variables increased significantly (P Doppler peak systolic velocities, and late diastolic velocities. Deceleration time of E-wave decreased significantly (P 0.05) changes in E/A, early diastolic tissue Doppler velocities (e'), and E/e'. Most, but not all variables returned to baseline values 110 minutes after food intake. This study shows that food intake affects several echocardiographic variables used to routinely assess diastolic function and hemodynamics. Further studies are warranted in older healthy subjects and in patients with various cardiac diseases to determine whether the findings are reproducible in such populations. © 2011, Wiley Periodicals, Inc.

  15. Steering A Radar Beam Toward The Zero-Doppler Line

    Science.gov (United States)

    Chang, Chi-Yung; Curlander, John C.

    1994-01-01

    Algorithm computes angles needed to aim radar beam from airborne or spaceborne platform toward Doppler line projected on ground for which Doppler shift of radar return is zero. Devised to reduce Doppler errors and simplify processing of data from synthetic-aperture-radar system. Applicable to aiming of other radio or optical instruments toward their zero-Doppler lines on ground.

  16. Simultaneous bilateral contrast transcranial doppler monitoring in patients with intracardiac and intrapulmonary shunts.

    Science.gov (United States)

    Horner, S; Ni, X S; Weihs, W; Harb, S; Augustin, M; Duft, M; Niederkorn, K

    1997-09-01

    The prevalence of a right-to-left intracardiac shunt, demonstrated by echocardiography and transcranial Doppler sonography has been shown to be higher in stroke patients than in normal controls. The aim of this study was to assess the sensitivity and specificity of contrast transcranial Doppler sonography in comparison to transesophageal echocardiography in the detection and differentiation of intracardiac and intrapulmonary shunts and to correlate the transcranial Doppler findings with clinical outcome and morphological findings. Forty five consecutive stroke patients with suspected paradoxical embolism were entered into the study. In all 25 patients with middle cerebral artery stroke of the left (56%) or right (44%) territory and echocardiographic demonstrated patent foramen ovale (80%) or intrapulmonary shunt (20%), simultaneous bilateral transcranial Doppler sonography of the middle cerebral arteries was performed after contrast medium injection during rest and valsalva straining under standardized and optimized conditions. Overall sensitivity for the detection of a right-to-left shunt by contrast transcranial Doppler sonography was 97% and overall specificity was 70%. Bilateral appearance of microbubbles, microbubble count and time delay of microbubble appearance significantly increased after valsalva straining. In patients with intracardiac shunts, a significantly higher microbubble count (32 vs. 13 in patients with an intrapulmonary shunt) and a shorter time interval of microbubble appearance (11 vs. 14 s in patients with intrapulmonary shunts) was observed. There was no correlation between the side and numerical distribution of microbubble count and the location and severity of the current clinical symptoms, as well as between microbubble count and presence and hemispherical distribution of brain infarcts. Transcranial Doppler sonography is a highly sensitive method for the detection of right-to-left shunts, whether of cardiac or pulmonary location. However

  17. Combination of serum angiopoietin-2 and uterine artery Doppler for prediction of preeclampsia.

    Science.gov (United States)

    Puttapitakpong, Ploynin; Phupong, Vorapong

    2016-02-01

    The aim of this study was to determine the predictive value of the combination of serum angiopoietin-2 (Ang-2) levels and uterine artery Doppler for the detection of preeclampsia in women at 16-18 weeks of gestation and to identify other pregnancy complications that could be predicted with these combined tests. Maternal serum Ang-2 levels were measured, and uterine artery Doppler was performed in 400 pregnant women. The main outcome was preeclampsia. The predictive values of this combination were calculated. Twenty-five women (6.3%) developed preeclampsia. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of uterine artery Doppler combined with serum Ang-2 levels for the prediction of preeclampsia were 24.0%, 94.4%, 22.2% and 94.9%, respectively. For the prediction of early-onset preeclampsia, the sensitivity, specificity, PPV and NPV were 57.1%, 94.1%, 14.8% and 99.2%, respectively. Patients with abnormal uterine artery Doppler and abnormal serum Ang-2 levels (above 19.5 ng ml(-1)) were at higher risk for preterm delivery (relative risk=2.7, 95% confidence interval 1.2-5.8). Our findings revealed that the combination of uterine artery Doppler and serum Ang-2 levels at 16-18 weeks of gestation can be used to predict early-onset preeclampsia but not overall preeclampsia. Thus, this combination may be a useful early second trimester screening test for the prediction of early-onset preeclampsia.

  18. Diagnosis of umbilical cord entanglement in a monochorionic diamniotic twin pregnancy with spontaneous septostomy of the dividing membranes using dual-gate Doppler imaging.

    Science.gov (United States)

    Ito, Ayumu; Nakata, Masahiko; Oji, Ayako; Takano, Mayumi; Umemura, Nahomi; Nagasaki, Sumito; Maemura, Toshimitsu; Morita, Mineto

    2018-01-01

    Umbilical cord entanglement is the leading cause of fetal mortality in monoamniotic twin pregnancies and a pseudo monoamniotic environment. Published methods for detecting this complication include color Doppler and pulsed Doppler sonography; however, no method provides an absolute diagnosis. In this case, we report the diagnosis of umbilical cord entanglement using dual-gate Doppler imaging. A 35-year-old woman was referred to our hospital at 28 weeks of gestation for prenatal management because of diagnosis of a monochorionic diamniotic twin pregnancy with spontaneous septostomy of the dividing membranes. Each fetus displayed normal fetal growth without obvious discordance and anatomical abnormalities. However, the dividing membrane was not detected, and an entangled cord was suspected. Dual-gate Doppler examination was carried out. Two regions of interest were considered at different areas of the umbilical arteries, and when each Doppler image showed two different heart rates at the same time, we considered this to be evidence of umbilical cord entanglement. Cesarean section was performed at 32 weeks of gestation and twins were delivered. The delivered umbilical cords had sixfold entanglement. In this case, dual-gate Doppler seems to have been more accurate than conventional single-gate Doppler for the diagnosis of cord entanglement because we confirmed two different heart rates at the same time with dual-gate Doppler.

  19. High Throughput Direct Detection Doppler Lidar Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Lite Cycles, Inc. (LCI) proposes to develop a direct-detection Doppler lidar (D3L) technology called ELITE that improves the system optical throughput by more than...

  20. Student Microwave Experiments Involving the Doppler Effect.

    Science.gov (United States)

    Weber, F. Neff; And Others

    1980-01-01

    Described is the use of the Doppler Effect with microwaves in the measurement of the acceleration due to gravity of falling objects. The experiments described add to the repertoire of quantitative student microwave experiments. (Author/DS)

  1. Doppler effect induced spin relaxation boom

    National Research Council Canada - National Science Library

    Zhao, Xinyu; Huang, Peihao; Hu, Xuedong

    2016-01-01

    .... We find that Doppler effect leads to several interesting phenomena. In particular, spin relaxation rate peaks when the QD motion is in the transonic regime, which we term a spin relaxation boom in analogy to the classical sonic boom...

  2. Doppler vortography: a color Doppler approach for quantification of the intraventricular blood flow vortices

    Science.gov (United States)

    Mehregan, Forough; Tournoux, François; Muth, Stéphan; Pibarot, Philippe; Rieu, Régis; Cloutier, Guy; Garcia, Damien

    2013-01-01

    We propose a new approach for quantification of intracardiac vorticity – Doppler vortography – based on conventional color Doppler images. Doppler vortography relies on the centrosymmetric properties of the vortices. Such properties induce particular symmetries in the Doppler flow data which can be exploited to describe the vortices quantitatively. For this purpose, a kernel filter was developed to derive a parameter –the blood vortex signature (BVS) – that allows detecting the main intracardiac vortices and estimating their core vorticities. The reliability of Doppler vortography was assessed in mock Doppler fields issued from simulations and in vitro data. Doppler vortography was also tested in patients and compared with vector flow mapping by echocardiography. Strong correlations were obtained between the Doppler vortography-derived and the ground-truth vorticities (in silico: r2 = 0.98, in vitro: r2 = 0.86, in vivo: r2 = 0.89). Our results demonstrated that Doppler vortography is a potentially promising echocardiographic tool for quantification of vortex flow in the left ventricle. PMID:24210865

  3. Doppler vortography: a color Doppler approach to quantification of intraventricular blood flow vortices.

    Science.gov (United States)

    Mehregan, Forough; Tournoux, François; Muth, Stéphan; Pibarot, Philippe; Rieu, Régis; Cloutier, Guy; Garcia, Damien

    2014-01-01

    We propose a new approach to quantification of intracardiac vorticity based on conventional color Doppler images -Doppler vortography. Doppler vortography relies on the centrosymmetric properties of the vortices. Such properties induce particular symmetries in the Doppler flow data that can be exploited to describe the vortices quantitatively. For this purpose, a kernel filter was developed to derive a parameter, the blood vortex signature (BVS), that allows detection of the main intracardiac vortices and estimation of their core vorticities. The reliability of Doppler vortography was assessed in mock Doppler fields issued from simulations and in vitro data. Doppler vortography was also tested in patients and compared with vector flow mapping by echocardiography. Strong correlations were obtained between Doppler vortography-derived and ground-truth vorticities (in silico: r2 = 0.98, in vitro: r2 = 0.86, in vivo: r2 = 0.89). Our results indicate that Doppler vortography is a potentially promising echocardiographic tool for quantification of vortex flow in the left ventricle. Copyright © 2014 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  4. De-Dopplerization of Acoustic Measurements

    Science.gov (United States)

    2017-08-10

    band energy obtained from fractional octave band digital filters generates a de-Dopplerized spectrum without complex resampling algorithms. An...energy obtained from fractional octave band digital filters generates a de-Dopplerized spectrum without complex resampling algorithms. An equation...observer case. Previous efforts using a fixed array to record acoustic emissions, resulting from the motion of the acoustic source only, have been

  5. Abnormal Head Position

    Science.gov (United States)

    ... non-ocular causes of an abnormal head position? Congenital shortening of the neck muscles (sternocleidomastoid) can cause a head tilt. This is ... amblyopia) are other treatment alternatives. Physical therapy helps congenital torticollis from tight neck muscles. Updated ... Terms & Conditions Most Common ...

  6. Acute Fetal Anemia Diagnosed by Middle Cerebral Artery Doppler Velocimetry in Stage V Twin–Twin Transfusion Syndrome

    Directory of Open Access Journals (Sweden)

    Jennifer Salcedo

    2011-12-01

    Full Text Available In stage V twin–twin transfusion syndrome (TTTS, up to 50% of surviving twins die or experience permanent disabilities, likely due to acute intertwin hemorrhage resulting in sudden severe anemia of the survivor. Although fetal middle cerebral artery (MCA Doppler studies demonstrate strong correlation with fetal hemoglobin values, acute hemorrhagic events are more difficult to diagnose, and optimal timing of delivery of the survivor poses an obstetric dilemma. We report a case of newly diagnosed stage V TTTS at 28 weeks gestation, complicated by acute severe anemia diagnosed by significantly abnormal fetal MCA Doppler studies. The anemic twin was urgently delivered and is doing well without significant sequelae.

  7. Doppler velocimetry in cavitating media.

    Science.gov (United States)

    Pindera, M Z; Siegel, J M; Makhijani, V B

    1997-01-01

    A numerical model has been developed to simulate propagation of ultrasonic beams in inhomogeneous moving media. The model is based on the ray theory of propagating waves, valid in the limit of high frequencies. The resulting equations depend only on local values of the velocity field and the speed of sound. In its implementation, the model assumes that the interactions of sound with the surrounding flow field are decoupled. This allows for applying the model in a post processing mode to flows computed by other means. The model was used to investigate beam behavior in unsteady cavitating flows. The study was motivated by reports of cavitation occurring in mitral bi-leaflet mechanical heart valves. The flow field and cavitation physics were simulated using a general purpose computer code, CFD-ACE. The ultrasonic beam model was then used to calculate the beam path, orientation, and frequency changes in the transient cavitating region. Results show that the presence of cavitation can fundamentally alter the beam propagation characteristics. Simple models that assume rectilinear propagation cannot, by definition, handle such flows. Cavitation incurs very large variations in the local sound speed, which in turn can induce very large distortions in the beam. This fact has strong ramifications regarding the accuracy of ultrasonic velocimetry when simple models are used to interpret Doppler data gathered under such flow conditions.

  8. CERN openlab enters fifth phase

    CERN Multimedia

    Andrew Purcell

    2015-01-01

    CERN openlab is a unique public-private partnership between CERN and leading ICT companies. At the start of this year, openlab officially entered its fifth phase, which will run until the end of 2017. For the first time in its history, it has extended beyond the CERN community to include other major European and international research laboratories.   Founded in 2001 to develop the innovative ICT systems needed to cope with the unprecedented computing challenges of the LHC, CERN openlab unites science and industry at the cutting edge of research and innovation. In a white paper published last year, CERN openlab set out the main ICT challenges it will tackle during its fifth phase, namely data acquisition, computing platforms, data storage architectures, computer management and provisioning, networks and connectivity, and data analytics. As it enters its fifth phase, CERN openlab is expanding to include other research laboratories. "Today, research centres in other disciplines are also st...

  9. [Enteral feeding in adults: indications].

    Science.gov (United States)

    Matuchansky, C

    1991-03-11

    In this overview article the author examines successively: (1) the effects expected from enteral nutrition in adults: general and/or local nutritional effects, temporary arrest in progressive intestinal lesions, partial intestinal function replacement; (2) indications in gastrointestinal and non-gastrointestinal pathologies and modalities of application to each indication (route of administration, elemental, semi-elemental or polymeric nutrients, incremental or non-incremental calorie intake, necessity or lack of necessity for addition of fibres, value of ambulatory methods); (3) results according to indications: chronic inflammatory intestinal diseases, notably Crohn's disease, short small bowel syndromes, fistulae and stomies, preoperative period in gastrointestinal surgery, support of heavy treatments in non-terminal cancers, hypermetabolic states, notably stress; (4) absolute or relative contraindications of enteral nutrition.

  10. Enteral feeding without pancreatic stimulation

    DEFF Research Database (Denmark)

    Kaushik, Neeraj; Pietraszewski, Marie; Holst, Jens Juul

    2005-01-01

    .5 g protein/kg ideal body weight/d. Plasma gut peptide responses were monitored in 15 subjects. RESULTS: In comparison with basal fasting trypsin secretion rates (mean = 134 [standard error = 22] U/h), duodenal feeding with the polymeric and elemental formulae stimulated trypsin secretion (mean = 408...... in enteral feeding without pancreatic stimulation, with particular reference to trypsin, because the avoidance of trypsin stimulation may optimize enteral feeding in acute pancreatitis. METHODS: The pancreatic secretory responses to feeding were studied in 36 healthy volunteers by standard double...... [standard error = 51] U/h; P standard error = 34] U/h) and mid-distal jejunal (mean = 119 [standard error = 16] U/h) did not. Stimulation was associated with an increase in plasma cholecystokinin, whereas distal jejunal feeding resulted in an increase...

  11. Enteral alimentation: administration and complications.

    Science.gov (United States)

    Benya, R; Mobarhan, S

    1991-06-01

    Tube feeding is commonly used for providing essential calories and nutrients to the patient otherwise unable to eat. In the last two decades there has been significant expansion in the number and quality of enteral formulas. In this review, we evaluate the indications for each major class of formula, and survey complications associated with formulas and devices that deliver formula. Recommendations for future research are listed.

  12. A Map Enters the Conversation

    DEFF Research Database (Denmark)

    Munk, Anders Kristian

    'modes of mattering'. In this paper I explore what difference digital cartography can make to STS practice. I draw on three examples from my own work where digitally mediated maps have entered the conversation and made critical, often surprising, differences to the research process. In my first example...... it was trying to chart. I use these examples to discuss the potential modes of mattering afforded by digital cartography in STS....

  13. Ultrasonography with color Doppler and power Doppler in the diagnosis of periapical lesions

    Directory of Open Access Journals (Sweden)

    Sumit Goel

    2011-01-01

    Full Text Available Aim: To evaluate the efficacy of ultrasonography (USG with color Doppler and power Doppler applications over conventional radiography in the diagnosis of periapical lesions. Materials and Methods: Thirty patients having inflammatory periapical lesions of the maxillary or mandibular anterior teeth and requiring endodontic surgery were selected for inclusion in this study. All patients consented to participate in the study. We used conventional periapical radiographs as well as USG with color Doppler and power Doppler for the diagnosis of these lesions. Their diagnostic performances were compared against histopathologic examination. All data were compared and statistically analyzed. Results: USG examination with color Doppler and power Doppler identified 29 (19 cysts and 10 granulomas of 30 periapical lesions accurately, with a sensitivity of 100% for cysts and 90.91% for granulomas and a specificity of 90.91% for cysts and 100% for granulomas. In comparison, conventional intraoral radiography identified only 21 lesions (sensitivity of 78.9% for cysts and 45.4% for granulomas and specificity of 45.4% for cysts and 78.9% for granulomas. There was definite correlation between the echotexture of the lesions and the histopathological features except in one case. Conclusions: USG imaging with color Doppler and power Doppler is superior to conventional intraoral radiographic methods for diagnosing the nature of periapical lesions in the anterior jaws. This study reveals the potential of USG examination in the study of other jaw lesions.

  14. Ultrasonography with color Doppler and power Doppler in the diagnosis of periapical lesions

    Science.gov (United States)

    Goel, Sumit; Nagendrareddy, Suma Gundareddy; Raju, Manthena Srinivasa; Krishnojirao, Dayashankara Rao Jingade; Rastogi, Rajul; Mohan, Ravi Prakash Sasankoti; Gupta, Swati

    2011-01-01

    Aim: To evaluate the efficacy of ultrasonography (USG) with color Doppler and power Doppler applications over conventional radiography in the diagnosis of periapical lesions. Materials and Methods: Thirty patients having inflammatory periapical lesions of the maxillary or mandibular anterior teeth and requiring endodontic surgery were selected for inclusion in this study. All patients consented to participate in the study. We used conventional periapical radiographs as well as USG with color Doppler and power Doppler for the diagnosis of these lesions. Their diagnostic performances were compared against histopathologic examination. All data were compared and statistically analyzed. Results: USG examination with color Doppler and power Doppler identified 29 (19 cysts and 10 granulomas) of 30 periapical lesions accurately, with a sensitivity of 100% for cysts and 90.91% for granulomas and a specificity of 90.91% for cysts and 100% for granulomas. In comparison, conventional intraoral radiography identified only 21 lesions (sensitivity of 78.9% for cysts and 45.4% for granulomas and specificity of 45.4% for cysts and 78.9% for granulomas). There was definite correlation between the echotexture of the lesions and the histopathological features except in one case. Conclusions: USG imaging with color Doppler and power Doppler is superior to conventional intraoral radiographic methods for diagnosing the nature of periapical lesions in the anterior jaws. This study reveals the potential of USG examination in the study of other jaw lesions. PMID:22223940

  15. Neurological abnormalities predict disability

    DEFF Research Database (Denmark)

    Poggesi, Anna; Gouw, Alida; van der Flier, Wiesje

    2014-01-01

    To investigate the role of neurological abnormalities and magnetic resonance imaging (MRI) lesions in predicting global functional decline in a cohort of initially independent-living elderly subjects. The Leukoaraiosis And DISability (LADIS) Study, involving 11 European centres, was primarily aimed...... at evaluating age-related white matter changes (ARWMC) as an independent predictor of the transition to disability (according to Instrumental Activities of Daily Living scale) or death in independent elderly subjects that were followed up for 3 years. At baseline, a standardized neurological examination.......0 years, 45 % males), 327 (51.7 %) presented at the initial visit with ≥1 neurological abnormality and 242 (38 %) reached the main study outcome. Cox regression analyses, adjusting for MRI features and other determinants of functional decline, showed that the baseline presence of any neurological...

  16. Characteristics of Three-Dimensional Power Doppler in Gestational Trophoblastic Disease

    Directory of Open Access Journals (Sweden)

    Wei Wang

    2015-01-01

    Full Text Available Purpose. In the present study, the three-dimensional power Doppler was used as a quantitative method to evaluate its reliability in detecting and assessing of gestational trophoblastic disease (GTD. Methods. 52 GTD patients who received diagnosis and treatment at the first affiliated hospitals of Xi’an Jiaotong University in China between 2011 and 2013 were evaluated using Voluson E8 (GE Medical System. Demographic information, pathological characteristics, clinical history, sonographic images, and related indices (resistance index, vascularization index, and flow and vascularization index were evaluated. Result. Three-dimension power Doppler indicated that there were significant differences in the resistance index, vascularization index, flow index, and vascularization-flow index between the healthy individuals and each subgroup of patients (P<0.01. Further, in combining invasive hydatidiform mole and choriocarcinoma groups, there was a significant difference between hydatidiform mole and the combined malignant group (P<0.01. And the abnormal sonographic and power Doppler findings in GTD were resolved when chemotherapy was done successfully. Conclusion. Combined with the clinical features, sonography and three-dimension power Doppler imaging were helpful in diagnosing GTD as a noninvasive method, distinguishing the invasive nature of disease, detecting the recurrence of the disease, and assessing the effectiveness of the chemotherapy.

  17. The effect of Ramadan fasting on fetal growth and Doppler indices of pregnancy.

    Science.gov (United States)

    Moradi, Maryam

    2011-02-01

    The aim of this study was to determine the effect of Ramadan fasting on fetal growth and Doppler in-dices of pregnancy. Fifty two healthy pregnant women of second or third trimester, 25 in fasting group and 27 in non fasting group were included. Growth parameters including biparietal diameter (BPD), femoral length (FL), abdominal circumference (AC), estimated fetal weight, amniotic fluid index and also Doppler indices of both uterine and umbilical arteries (including peak systolic and end diastolic velocity, systolic to diastolic ratio, resistive and pulsatility indices) were evaluated by Gray scale and colour Doppler imaging for each women two times, in the beginning and at the end of Ramadan. Increases in BPD, FL, AC and fetal weight within one month were similar in two groups. Amniotic fluid index also were similar in two groups. There was not any statistically significant difference in abnormal Doppler indices of uterine or umbilical artery between two groups. The results of present study show that Ramadan fasting has no adverse effect on fetal growth, amniotic fluid volume or maternofetal circulation.

  18. Significance of CT scan and color Doppler duplex ultrasound in the assessment of Abernethy malformation.

    Science.gov (United States)

    Nacif, Lucas Souto; Paranaguá-Vezozzo, Denise Cerqueira; Galvão, Flávio Henrique Ferreira; Rocha, Manoel S; Andraus, Wellington; Carrilho, Flair Jose; D'Albuquerque, Luiz Carneiro

    2015-09-18

    Abernethy malformation is a rare congenital vascular abnormality in which the portal vein bypasses the liver and drains directly into the inferior vena cava. Diagnosis is complex and requires good quality imaging methods to identify details in systemic and portal circulation in order to establish diagnostic confirmation and treatment strategy. In this study we highlight the significance of the use of CT scans and Color Doppler Duplex Ultrasound for the diagnosis, treatment and evolution assessment in two adults with Abernethy malformation. The diagnosis and the treatment of two patients with Abernethy malformation by CT scan and Color Doppler Duplex Ultrasound is described. One patient was submitted to liver transplantation due to chronic liver disease and multiple nodules diagnosed as adenoma. The other patient had normal liver function and a mild neurological and psychomotor dysfunction, therefore we adopted clinical treatment and close liver parenchyma evaluation and nodule surveillance, using an imaging approach involving intercalating CT scan and Color Doppler Duplex Ultrasound every 6 months. We highlight some important direct and indirect findings of non-invasive imaging methods. Abernethy malformation requires meticulous image diagnosis to improve treatment and avoid iatrogenic procedures. CT scans and Color Doppler Duplex Ultrasound are both efficient methods for diagnosis, treatment planning and evolution assessment of patients with Abernethy malformation.

  19. Abnormal Uterine Bleeding

    OpenAIRE

    Benetti-Pinto, Cristina Laguna; Rosa-e-Silva, Ana Carolina Japur de Sá; Yela, Daniela Angerame; Soares Júnior,José Maria

    2017-01-01

    Abstract Abnormal uterine bleeding is a frequent condition in Gynecology. It may impact physical, emotional sexual and professional aspects of the lives of women, impairing their quality of life. In cases of acute and severe bleeding, women may need urgent treatment with volumetric replacement and prescription of hemostatic substances. In some specific cases with more intense and prolonged bleeding, surgical treatment may be necessary. The objective of this chapter is to describe the main evi...

  20. Comparison of perinatal outcome in growth restricted fetuses retaining normal umbilical artery Doppler flow to those with diminished end-diastolic flow.

    Science.gov (United States)

    Siddiqui, Tariq Saeed; Asim, Aisha; Ali, Shafqut; Siddiqui, Tahir Saeed; Tariq, Asima

    2014-01-01

    Intrauterine growth restriction /retardation (IUGR) is defined as birth weight below the 10th percentile for a given gestational age. Placental insufficiency is the primary cause of intrauterine growth retardation in normally formed fetuses and can be identified using umbilical artery Doppler velocimetry which is a non-invasive technique. The objective of this study was to compare perinatal outcome in growth restricted fetuses retaining normal umbilical artery Doppler flow to those with diminished or severely reduced/absent end-diastolic flow. This cross sectional study was conducted at Radiology department of Pakistan Navy Ship (PNS) Shifa Hospital, Karachi over one year period from. Established cases of asymmetrical IUGR, having estimated fetal weight < 10th percentile for gestational age and between 28-40 weeks of gestation were included in the study. Pulsatility index (PI) was calculated for each case. Perinatal outcomes like early delivery, caesarean section, respiratory distress syndrome, necrotizing enterocolitis, admission to neonatal ICU, prenatal and neonatal death were evaluated. Chi-square test was used to compare proportion difference of perinatal outcomes for normal and abnormal umbilical artery velocimetry, with 0.05 level of significance. Umbilical artery Doppler velocimetry showed a significant correlation with the perinatal outcome. In 90% of cases of IUGR having abnormal waveform, poor perinatal outcome was seen as compared to only 33.3% retaining normal Doppler flow. Growth restricted fetuses with normal umbilical artery Doppler velocimetry were at lower risk than those with abnormal waveforms.

  1. Editorial special issue on "Laser Doppler vibrometry"

    Science.gov (United States)

    Vanlanduit, Steve; Dirckx, Joris

    2017-12-01

    The invention of the laser in 1960 has opened up many opportunities in the field of measurement science and technology. Just a few years after the invention of the laser, a novel fluid flow measurement technique based on the Doppler effect was introduced: at that moment the laser Doppler anemometer or shortly LDA [1] was born. The technique enabled fluid velocity measurement by using the light of a He-Ne beam which was scattered by very small polystyrene spheres entrained in the fluid. Later on, in the late nineteen seventees it was recognized that the detection of the Doppler frequency shift that occurs when light is scattered by a moving surface can also be used to measure the vibration velocity of an object. The instrument to perform these vibration measurements was called the laser Doppler vibrometer or LDV [2]. In the last decades several technological advances were made in the field of laser Doppler vibrometry. The result is that nowadays, velocity measurements of fluids (using LDA) and vibrating objects (using LDV) are performed in many challenging applications in different fields (microelectronics, civil structures, biomedical engineering, material science, etc.).

  2. Development of the doppler electron velocimeter: theory.

    Energy Technology Data Exchange (ETDEWEB)

    Reu, Phillip L.

    2007-03-01

    Measurement of dynamic events at the nano-scale is currently impossible. This paper presents the theoretical underpinnings of a method for making these measurements using electron microscopes. Building on the work of Moellenstedt and Lichte who demonstrated Doppler shifting of an electron beam with a moving electron mirror, further work is proposed to perfect and utilize this concept in dynamic measurements. Specifically, using the concept of ''fringe-counting'' with the current principles of transmission electron holography, an extension of these methods to dynamic measurements is proposed. A presentation of the theory of Doppler electron wave shifting is given, starting from the development of the de Broglie wave, up through the equations describing interference effects and Doppler shifting in electron waves. A mathematical demonstration that Doppler shifting is identical to the conceptually easier to understand idea of counting moving fringes is given by analogy to optical interferometry. Finally, potential developmental experiments and uses of a Doppler electron microscope are discussed.

  3. Color Doppler artifact in anechoic regions.

    Science.gov (United States)

    Mitchell, D G; Burns, P; Needleman, L

    1990-05-01

    For color Doppler imaging, several types of signal processing are employed in order to produce acceptable images of blood flow in blood vessels while suppressing color in moving solid tissue. The processing can produce an artifact in which color may arise from noise or from tissue motion and fill anechoic regions preferentially. This artifact may complicate the differentiation of areas with blood flow from anechoic regions without flow. By using four different color Doppler ultrasound units to image a tissue-equivalent phantom containing anechoic cylinders, artifactual color resulted when gain was raised sufficiently. This color was concentrated in anechoic regions of a gray-scale image that did not contain flow. In two instruments, this artifact was only observed when the transducer was vibrated, simulating tissue motion. In these instruments, the identification of low-frequency, high-amplitude Doppler signals is used to locate moving solid tissue and so suppress color in these regions. In the other two instruments, the presence of echoes within the image suppressed the assignment of color. With both types of processing, color may appear artifactually in echo-free regions without flow, such as fluid collections. Presence or absence of flow should be confirmed by Doppler spectral analysis. An understanding of the origin and appearance of artifactual color can prevent its occurrence from detracting from the usefulness of color Doppler imaging.

  4. Enteric campylobacter: purging its secrets?

    Science.gov (United States)

    Crushell, Ellen; Harty, Sinead; Sharif, Farhana; Bourke, Billy

    2004-01-01

    Campylobacterial infections are the most common cause of bacterial enterocolitis in humans. Among children, especially in developing countries, Campylobacter infections can cause severe life-threatening diarrheal disease. Although usually associated with a benign outcome in the developed world, the burden of illness posed by Campylobacter infections is enormous, and serious neurologic sequelae also can occur. For a variety of reasons our understanding of the molecular and cellular pathogenesis of Campylobacter infection has lagged far behind that of other enteric pathogens. However, recent completion of the genome sequence of Campylobacter jejuni promises to open up the Campylobacter research field with the prospect of developing novel therapeutic and preventive strategies.

  5. Evolving trends in enteral alimentation.

    Science.gov (United States)

    Ponsky, J L

    1986-01-01

    Nutrition has become a cornerstone of surgical patient care. With better understanding of metabolic and compositional requirements, great advances have been made in the area of total parenteral nutrition. Recent attention to full utilization of alimentary tract function has prompted a resurgence of interest in dietary formulas and methods of delivery. Three new approaches to the alimentary tract provide better access for feeding. Needle catheter jejunostomy allows early alimentary tract utilization following operations, while percutaneous endoscopic gastrostomy and jejunostomy provide long-term solutions to the provision of enteral alimentation. Future utilization of these techniques will certainly lead to better patient care.

  6. The challenge of enteric fever.

    Science.gov (United States)

    Waddington, Claire S; Darton, Thomas C; Pollard, Andrew J

    2014-01-01

    Enteric fever, a non-specific, systemic infection caused by S. Typhi or Paratyphi A, B or C, is common in resource-limited regions of the world, where poor sanitation infrastructure facilitates faeco-oral transmission. Prompt treatment with appropriate antibiotics minimises illness severity, but presentation to health care facilities is often delayed because of the non-specific nature of the symptoms and the lack of reliable diagnostic tests. Disease prevention requires significant investment in provision of clean water and sanitation in the long term; vaccination offers a more realistic strategy for medium term control. However, implementation of existing vaccines and development of more efficacious vaccines has been hindered by the lack of an established correlate of protection and under appreciation of the true disease burden. Human microbial infection studies could provide a vehicle for the rapid evaluation of novel vaccines and investigation of the immunobiology of enteric infection. Copyright © 2013 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

  7. Drug distribution in enteric microparticles.

    Science.gov (United States)

    Nilkumhang, Suchada; Alhnan, Mohamed A; McConnell, Emma L; Basit, Abdul W

    2009-09-08

    The aim of this study was to assess the distribution of three fluorescent drug or drug-like molecules in enteric microparticles. Microparticles were prepared using the pH-responsive methylmethacrylate polymer Eudragit L by an emulsion solvent evaporation process. In the process drug and polymer are dissolved in ethanol, and dispersed in a liquid paraffin external phase using sorbitan sesquioleate as stabiliser. The incorporation and distribution of riboflavin, dipyridamole and acridine orange into these microparticles were investigated using confocal laser scanning microscopy (CLSM). The influence of the physicochemical properties of the molecules (solubility in the inner phase, partition coefficient [ethanol/paraffin]) on the distribution, encapsulation efficiency and pH-responsive dissolution behaviour of the microparticles were examined. The drug that tended to partition in ethanol rather than liquid paraffin (riboflavin) was efficiently encapsulated and evenly distributed. In contrast, compounds which partitioned in favour of the liquid paraffin localised towards the surface of the microparticles and exhibited lower encapsulation efficiency (dipyridamole and acridine orange). All three sets of drug-loaded microparticles showed a limited release in acid (distribution appeared to have a minimum effect on drug release. This microparticle technology has the potential to provide effective enteric drug release with a wide variety of molecules.

  8. [New nutrients in enteral nutrition].

    Science.gov (United States)

    Vázquez Martínez, C

    2000-01-01

    1. Medical and surgical stress (major surgery, sepsis, injuries,...) increases requirements of certain essential nutrients and others considered non-essential or semi-essential. 2. Some nutrients such as glutamine, arginine, omega 3 fatty acids nucleotides, ... have a considerable influence on the immune function (delayed hypersensitivity, lymphocyte sub-population counts, immunological tests,..) and improve certain metabolic and nutritional indices (nitrogen balance, medium and short life proteins,...). For this reason, they are called "immunonutrients" or "immunity regulators". 3. The supply of special enteral formulas for situations of immunological compromise, with the addition of one or more of the nutrients considered today as "immunity regulators" has increased since 1988 in both absolute and percentage terms. 4. These nutrient-enriched enteral formulas improve the rate of infections, reduce the number of days on ventilator equipment, the length of hospital stays for critical patients, with a more marked effect on surgical patients. 5. The evidence seems today to support the use of enriched formulas with critical patients. Nonetheless, some caution must be maintained as it has not been possible to show any reduction in the mortality of the cases studied nor, in short, in the prognosis of patients affected by situations of hypercatabolism and reduced immunity. 6. We feel that their use should, therefore, be carried out in accordance with the protocols and in patients expected to survive, where the evolution reveals severe catabolism unhindered by conventional therapy.

  9. Portal biliopathy diagnosed using color Doppler and contrast-enhanced ultrasound.

    Science.gov (United States)

    Nunoi, Hiroaki; Hirooka, Masashi; Ochi, Hironori; Koizumi, Yohei; Tokumoto, Yoshio; Abe, Masanori; Tada, Fujimasa; Ikeda, Yoshio; Matsuura, Bunzo; Tanaka, Hiroaki; Tsuda, Takaharu; Mochizuki, Teruhito; Hiasa, Yoichi; Onji, Morikazu

    2013-01-01

    Portal biliopathy is a morphological abnormality of the biliary ductal and gallbladder wall associated with portal hypertension. A patient with essential thrombocythemia was initially diagnosed with extrahepatic portal vein obstruction (EHPVO). The contrast-enhanced computed tomography (CT) findings were similar to those of cholangiocarcinoma or sclerosing cholangitis. However, color Doppler and contrast-enhanced ultrasound (US) were more specific. The paracholedocheal veins around the bile ducts appeared as beads soon after the injection of contrast medium, followed by linear enhancement of the epicholedochal veins and the gradual enhancement of the whole bile ducts. These findings led to a diagnosis of portal biliopathy, which prevented the patient from having to endure hazardous procedures such as bile duct biopsies. Color Doppler and contrast-enhanced US findings are useful for diagnosing or ruling out portal biliopathy in patients who present with EHPVO.

  10. Evaluation of Statens Serum Institut Enteric Medium for Detection of Enteric Pathogens

    OpenAIRE

    Blom, Marianne; Meyer, Aase; Gerner-Smidt, Peter; Gaarslev, Knud; Espersen, Frank

    1999-01-01

    The efficacy of the Statens Serum Institut (SSI) enteric medium for isolation and direct identification of enteric pathogens was evaluated. Six different biochemical reactions can be read by using the SSI enteric medium, allowing direct identification of a range of enteric pathogens. All 248 gram-negative bacterial species that were tested grew on the SSI enteric medium. Only 10 of 248 bacteria (4%) showed discrepant results in the biochemical reactions, and none of these were enteric pathoge...

  11. Diabetic Nephropathy : Evaluation with Doppler Ultrasonography

    Energy Technology Data Exchange (ETDEWEB)

    Sim, Jung Suk; Kim, Seung Hyup; Kang, Heung Sik; Park, Jae Hyung; Han, Man Chung [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    1996-06-15

    To compare Doppler ultrasonography with laboratory tests in evaluation of diabetic nephropathy. Fifty-five patients (mean age = 60, M : F = 26 : 29) with diabetes mellitus underwent renal Doppler ultrasonography. Resistive indices were compared with degree of proteinuria, serum creatinine level, and creatinine clearance rate. Eighteen patients who showed no proteinuria or microscopic proteinuria had a mean resistive index (RI) of 0.72 (SD, 0.05), 16 patients with macroscopic proteinuria without nephrotic syndrome had a mean RI of 0.82 (SD, 0.13), and 21 patients with nephrotic syndrome had a mean RI of 0.90 (SD, 0.12). Renal RI correlated highly with serum creatinine level (r = 0.62) and creatinine clearance rate (r = -0.43). Renal Doppler ultrasonography provides a useful indication of renal function in diabetic nephropathy but cannot offer an advantage over conventional laboratory test

  12. Role of nerves in enteric infection

    National Research Council Canada - National Science Library

    Spiller, R C

    2002-01-01

    Peripheral and central effects of enteric infection are considered. Nerves play a vital part in the immediate response to enteric infection, promoting pathogen expulsion by orchestrating intestinal secretion and propulsive motor patterns...

  13. Velocity measurement by vibro-acoustic Doppler.

    Science.gov (United States)

    Nabavizadeh, Alireza; Urban, Matthew W; Kinnick, Randall R; Fatemi, Mostafa

    2012-04-01

    We describe the theoretical principles of a new Doppler method, which uses the acoustic response of a moving object to a highly localized dynamic radiation force of the ultrasound field to calculate the velocity of the moving object according to Doppler frequency shift. This method, named vibro-acoustic Doppler (VAD), employs two ultrasound beams separated by a slight frequency difference, Δf, transmitting in an X-focal configuration. Both ultrasound beams experience a frequency shift because of the moving objects and their interaction at the joint focal zone produces an acoustic frequency shift occurring around the low-frequency (Δf) acoustic emission signal. The acoustic emission field resulting from the vibration of the moving object is detected and used to calculate its velocity. We report the formula that describes the relation between Doppler frequency shift of the emitted acoustic field and the velocity of the moving object. To verify the theory, we used a string phantom. We also tested our method by measuring fluid velocity in a tube. The results show that the error calculated for both string and fluid velocities is less than 9.1%. Our theory shows that in the worst case, the error is 0.54% for a 25° angle variation for the VAD method compared with an error of -82.6% for a 25° angle variation for a conventional continuous wave Doppler method. An advantage of this method is that, unlike conventional Doppler, it is not sensitive to angles between the ultrasound beams and direction of motion.

  14. Transcranial Doppler velocimetry in aneurysmal subarachnoid haemorrhage

    DEFF Research Database (Denmark)

    Staalsø, J M; Edsen, T; Romner, B

    2013-01-01

    BACKGROUND: /st>Transcranial Doppler measurements of the middle cerebral artery flow velocity are widely used as an indicator of vasospasm after aneurysmal subarachnoid haemorrhage (SAH). We investigated inter- and intraoperator agreement in SAH patients and healthy volunteers using colour......-coded transcranial Doppler (TCCD), with the secondary aim of describing prediction of angiographic vasospasm and mortality. METHODS: /st>Sixty patients and 70 healthy controls were each examined in duplicate by alternating operators. A total of 939 measurements divided on 201 examination sets were conducted by four...

  15. Selection effects in Doppler velocity planet searches

    Science.gov (United States)

    O'Toole, Simon; Tinney, Chris; Jones, Hugh

    2008-05-01

    The majority of extra-solar planets have been discovered by measuring the Doppler velocities of the host star. Like all exoplanet detection methods, the Doppler method is rife with observational biases. Before any robust comparison of mass, orbital period and eccentricity distributions can be made with theory, a detailed understanding of these selection effects is required, something which up to now is lacking. We present here a progress report on our analysis of the selection effects present in Anglo-Australian Planet Search data, including the methodology used and some preliminary results.

  16. Placental findings in late-onset SGA births without Doppler signs of placental insufficiency.

    Science.gov (United States)

    Parra-Saavedra, M; Crovetto, F; Triunfo, S; Savchev, S; Peguero, A; Nadal, A; Parra, G; Gratacos, E; Figueras, F

    2013-12-01

    To describe placental pathological findings in late-onset small-for-gestational age (SGA) births for which Doppler signs of placental insufficiency are lacking. A series of placentas were evaluated from singleton pregnancies of SGA births (birth weight below the 10th percentile) delivered after 34 weeks with normal umbilical artery Doppler (pulsatility index below the 95th percentile), that were matched by gestational age with adequate-for-gestational age (AGA) controls. Using a hierarchical and standardized system, placental lesions were classified histologically as consequence of maternal underperfusion, fetal underperfusion or inflammation. A total of 284 placentas were evaluated (142 SGA and 142 AGA). In the SGA group, 54.2% (77/142) of the placentas had weights below the 3rd percentile for GA while it was a 9.9% (14/142) in the AGA group (p SGA placentas were free of histological abnormalities, while it was 74.6% (106/142) in the AGA group (p SGA placentas (111/142) there were a total of 161 lesions, attributable to MUP in 64% (103/161), FUP in 15.5% (25/161), and inflammation in 20.5% (33/161). In most placentas of term SGA neonates with normal UA Doppler histological abnormalities secondary to maternal underperfusion prevail, reflecting latent insufficiency in uteroplacental blood supply. This is consistent with the higher risk of adverse perinatal outcome reported in this population and underscores a need for new markers of placental disease. A significant proportion of late-onset SGA births with normal umbilical artery Doppler may still be explained by placental insufficiency. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. Advantages of enteral nutrition over parenteral nutrition

    OpenAIRE

    Seres, David S.; Valcarcel, Monika; Guillaume, Alexandra

    2013-01-01

    It is a strong and commonly held belief among nutrition clinicians that enteral nutrition is preferable to parenteral nutrition. We provide a narrative review of more recent studies and technical reviews comparing enteral nutrition with parenteral nutrition. Despite significant weaknesses in the existing data, current literature continues to support the use of enteral nutrition in patients requiring nutrition support, over parenteral nutrition.

  18. Advantages of enteral nutrition over parenteral nutrition

    Science.gov (United States)

    Valcarcel, Monika; Guillaume, Alexandra

    2013-01-01

    It is a strong and commonly held belief among nutrition clinicians that enteral nutrition is preferable to parenteral nutrition. We provide a narrative review of more recent studies and technical reviews comparing enteral nutrition with parenteral nutrition. Despite significant weaknesses in the existing data, current literature continues to support the use of enteral nutrition in patients requiring nutrition support, over parenteral nutrition. PMID:23503324

  19. Pulsed photoacoustic Doppler flow measurements in blood-mimicking phantoms

    Science.gov (United States)

    Brunker, J.; Beard, P.

    2011-03-01

    The feasibility of making spatially resolved measurements of blood flow using pulsed photoacoustic Doppler techniques has been explored. Doppler time shifts were quantified via cross-correlation of pairs of photoacoustic waveforms generated within a blood-simulating phantom using pairs of laser light pulses. The photoacoustic waves were detected using a focussed or planar PZT ultrasound transducer. For each flow measurement, a series of 100 waveform pairs was collected. Previous data processing methods involved rejection of poorly correlated waveform pairs; the modal velocity value and standard deviation were then extracted from the selected distribution of velocity measurements. However, the data selection criteria used in this approach is to some extent arbitrary. A new data analysis protocol, which involves averaging the 100 cross-correlation functions and thus uses all of the measured data, has been designed in order to prevent exclusion of outliers. This more rigorous approach has proved effective for quantifying the linear motion of micron-scale absorbers imprinted on an acetate sheet moving with velocities in the range 0.14 to 1.25 ms-1. Experimental parameters, such as the time separation between the laser pulses and the transducer frequency response, were evaluated in terms of their effect on the accuracy, resolution and range of measurable velocities. The technique was subsequently applied to fluid phantoms flowing at rates less than 5 mms-1 along an optically transparent tube. Preliminary results are described for three different suspensions of phenolic resin microspheres, and also for whole blood. Velocity information was obtained even under non-optimal conditions using a low frequency transducer and a low pulse repetition frequency. The distinguishing advantage of pulsed rather than continuous-wave excitation is that spatially resolved velocity measurements can be made. This offers the prospect of mapping flow within the microcirculation and thus

  20. Doppler Sonography and 3D CT Angiography of Acquired Uterine Arteriovenous Malformations (AVMs): Report of Two Cases.

    Science.gov (United States)

    Aiyappan, Senthil Kumar; Ranga, Upasana; Veeraiyan, Saveetha

    2014-02-01

    Uterine Arteriovenous Malformations (AVMs) are rare but life threatening causes of abnormal vaginal bleeding. Accurate clinical and radiological diagnosis is essential because uterine instrumentation that is often used for management of other sources of abnormal bleeding, can lead to massive hemorrhage. Timely diagnosis and early proper treatment can markedly reduce the associated disease mortality. Ultrasound with colour and spectral doppler is the initial imaging modality of choice. Three-dimensional computed tomography (CT) angiography can determine the actual extent of the vascular malformation and helps in pre-interventional planning noninvasively. Uterine AVM can be either congenital or acquired in nature with latter being more common. We hereby report two cases of acquired AVMs diagnosed by color doppler sonography and confirmed by three-dimensional CT angiography. Both the cases reported here had previous history of dilation and curettage for abortion. Clinically one patient presented with profuse uterine bleeding and another with meno-metrorrhagia and both cases underwent surgical removal of uterus.

  1. GRIP DOPPLER AEROSOL WIND LIDAR (DAWN) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The GRIP Doppler Aerosol WiNd Lidar (DAWN) Dataset was collected by the Doppler Aerosol WiNd (DAWN), a pulsed lidar, which operated aboard a NASA DC-8 aircraft...

  2. ISAR imaging using the instantaneous range instantaneous Doppler method

    CSIR Research Space (South Africa)

    Wazna, TM

    2015-10-01

    Full Text Available In Inverse Synthetic Aperture Radar (ISAR) imaging, the Range Instantaneous Doppler (RID) method is used to compensate for the nonuniform rotational motion of the target that degrades the Doppler resolution of the ISAR image. The Instantaneous Range...

  3. TCSP ER-2 DOPPLER RADAR (EDOP) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The EDOP provides vertically profiled reflectivity and Doppler velocity at aircraft nadir along the flight track. The ER-2 Doppler radar (EDOP) is an X-band (9.6...

  4. Operational Bright-Band Snow Level Detection Using Doppler Radar

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A method to detect the bright-band snow level from radar reflectivity and Doppler vertical velocity data collection with an atmospheric profiling Doppler radar. The...

  5. Comparison of power Doppler and color Doppler ultrasonography in the detection of intrasticular blood flow of normal infants

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Sung Ran; Lee, Ho Kyoung; Lee, Won Gyun; Youk, Dong Joon; Rho, Taek Soo; Lee, Min Jin; Lee, Sang Chun [Seoul Red Cross Hospital, Seoul (Korea, Republic of)

    1999-09-15

    To compare color Doppler ultrasonography (US) and power Doppler US in the detection of intratesticular blood flow in normal infants and to asses the symmetry of blood flow. Testicular blood flow was assessed prospectively in 100 testes of 50 infants with both power and color Doppler US. We compared the power Doppler with color Doppler to detect intratesticular blood. When the flow was detected, intratesticular blood flow was graded as follows: grade 1: single intratesticular Doppler signal ; grade 2: multiple intratesticular Doppler signals. The symmetry of intratesticular flow was assessed by using the same method. Intratesticular flow was detected in 72 (72%) and 68 (68%) testes on power and color Doppler US, respectively. In 76 testes (76%), intratesticular flow was detected in either one or both techniques. On power Doppler US, grade 1 was seen in 40 tests and grade 2 in 32 testes. On color Doppler US, grade 1 was noted in 52 testes and grade 2 in 16 testes. Testicular blood flow was symmetric on both power and color Doppler US in each patient. There was no difference between power Doppler and color Doppler ultrasonography in detecting intratesticular blood flow in normal infants.

  6. Abnormal Cerebrovascular Reactivity in Patients with Parkinson’s Disease

    Directory of Open Access Journals (Sweden)

    Carlos Henrique Ferreira Camargo

    2015-01-01

    Full Text Available Background. Orthostatic hypotension (OH is an important nonmotor manifestation of Parkinson’s disease (PD. Changes in cerebrovascular reactivity may contribute to this manifestation and can be monitored using transcranial Doppler. Objective. To identify possible changes in cerebrovascular reactivity in patients with OH. Methods. Twenty-two individuals were selected and divided into three groups: with and without OH and controls. Transcranial Doppler was used to assess basal mean blood flow velocity, postapnea mean blood flow velocity, percentage increase in mean blood flow velocity, and cerebrovascular reactivity as measured by the breath-holding index. Results. PD patients had lower values of basal velocity (p=0.019, postapnea velocity (p=0.0015, percentage increase in velocity (p=0.039, and breath-holding index (p=0.04 than the controls. Patients with OH had higher values of basal velocity (p=0.09 and postapnea velocity (p=0.19 but lower values of percentage increase in velocity (p=0.22 and breath-holding index (p=0.32 than patients without OH. Conclusions. PD patients present with abnormalities in a compensatory mechanism that regulates cerebral blood flow. OH could be an indicator of these abnormalities.

  7. Photoacoustic Doppler flow measurement in optically scattering media

    OpenAIRE

    Fang, Hui; Maslov, Konstantin; Wang, Lihong V.

    2007-01-01

    We recently observed the photoacoustic Doppler effect from flowing small light-absorbing particles. Here, we apply the effect to measure blood-mimicking fluid flow in an optically scattering medium. The light scattering in the medium decreases the amplitude of the photoacoustic Doppler signal but does not affect either the magnitude or the directional discrimination of the photoacoustic Doppler shift. This technology may hold promise for a new Doppler method for measuring blood flow in microc...

  8. Rotational Doppler effect in left-handed materials

    OpenAIRE

    Luo, Hailu; Wen, Shuangchun; Shu, Weixing; Tang, Zhixiang; Zou, Yanhong; Fan, Dianyuan

    2008-01-01

    We explain the rotational Doppler effect associated with light beams carrying with orbital angular momentum in left-handed materials (LHMs). We demonstrate that the rotational Doppler effect in LHMs is unreversed, which is significantly different from the linear Doppler effect. The physics underlying this intriguing effect is the combined contributions of negative phase velocity and inverse screw of wave-front. In the normal dispersion region, the rotational Doppler effect induces a upstream ...

  9. Radar micro-doppler signatures processing and applications

    CERN Document Server

    Chen, Victor C; Miceli, William J

    2014-01-01

    Radar Micro-Doppler Signatures: Processing and applications concentrates on the processing and application of radar micro-Doppler signatures in real world situations, providing readers with a good working knowledge on a variety of applications of radar micro-Doppler signatures.

  10. On acceleration dependence of Doppler effect in light

    Indian Academy of Sciences (India)

    Using only the geometric relationships of suitable locations, we analyse Doppler effect in light to show how the acceleration of the source also contributes to the Doppler shift. We further propose that an experiment be performed using cyclotron-type devices to determine the acceleration dependence of the Doppler shift.

  11. Extraction of Doppler Scintillation from Deep Space Probe Tracking Data

    OpenAIRE

    Yamamoto, Zenichi; Toriyama, Gaku; Hirosawa, Haruto; 山本, 善一; 鳥山, 学; 廣澤, 春任

    1990-01-01

    Doppler frequencies of deep space probe tracking signalsfluctuate randomly when solar wind passes across ray-pathes of the radio waves. In this paper we present a method to extract Doppler scintillations from deep space probe tracking signals by applying filterings. We discuss the Doppler scintillations extracted from the tracking data of "SAKIGAKE" and "SUISEI".

  12. Path length resolved optical Doppler perfusion monitoring

    NARCIS (Netherlands)

    Varghese, Babu

    2007-01-01

    Laser Doppler blood flowmetry is a non-invasive technique for monitoring blood microcirculation in biological tissues and has been used in clinics for last three decades [1]. In spite of its important advantages such as high spatial resolution, noninvasiveness and real-time monitoring, this

  13. Path length resolved optical Doppler flowmetry

    NARCIS (Netherlands)

    Varghese, Babu; Rajan, Vinayakrishnan; van Leeuwen, Ton; Steenbergen, Wiendelt; Wax, Adam; Backman, Vadim

    2009-01-01

    The readings in laser Doppler perfusion monitoring are affected by the optical properties of the tissue in which the microvasculature is embedded, through their effect on the optical path lengths. Thus for a constant perfusion, the LDF output signal is affected by the variance in individual photon

  14. Quantum Theory of the Doppler Effect

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 10. Quantum Theory of the Doppler Effect. G S Ranganath. Classroom Volume 1 Issue 10 October 1996 pp 76-78. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/001/10/0076-0078 ...

  15. Method for Canceling Ionospheric Doppler Effect

    Science.gov (United States)

    Vessot, R. F. C.

    1982-01-01

    Unified transponder system with hydrogen-maser oscillators at both stations can compensate for both motional and ionospheric components of Doppler shift. Appropriate choices of frequency shift in output of mixer m3. System exploits proportionality between dispersive component of frequency shift and reciprocal of frequency to achieve cancellation of dispersive component at output.

  16. Doppler sonographic evaluation of venogenic extremity swellings ...

    African Journals Online (AJOL)

    Doppler ultrasound is very useful in the evaluation of extremity DVT. All clinically suspected cases should be evaluated with this modality due to limited sensitivity of clinical evaluation in the diagnosis of DVT. Further correlative studies in comparison to venography and hematologic indices are also recommended.

  17. Doppler Shift Compensation Schemes in VANETs

    Directory of Open Access Journals (Sweden)

    F. Nyongesa

    2015-01-01

    Full Text Available Over the last decade vehicle-to-vehicle (V2V communication has received a lot of attention as it is a crucial issue in intravehicle communication as well as in Intelligent Transportation System (ITS. In ITS the focus is placed on integration of communication between mobile and fixed infrastructure to execute road safety as well as nonsafety information dissemination. The safety application such as emergence alerts lays emphasis on low-latency packet delivery rate (PDR, whereas multimedia and infotainment call for high data rates at low bit error rate (BER. The nonsafety information includes multimedia streaming for traffic information and infotainment applications such as playing audio content, utilizing navigation for driving, and accessing Internet. A lot of vehicular ad hoc network (VANET research has focused on specific areas including channel multiplexing, antenna diversity, and Doppler shift compensation schemes in an attempt to optimize BER performance. Despite this effort few surveys have been conducted to highlight the state-of-the-art collection on Doppler shift compensation schemes. Driven by this cause we survey some of the recent research activities in Doppler shift compensation schemes and highlight challenges and solutions as a stock-taking exercise. Moreover, we present open issues to be further investigated in order to address the challenges of Doppler shift in VANETs.

  18. Doppler-ultralydundersøgelse af underekstremitetsarteriosklerose

    DEFF Research Database (Denmark)

    Rørdam, P; von Jessen, F; Sillesen, H H

    1992-01-01

    Arteriography, which requires resources and is not entirely without risk, has hitherto been a prerequisite for reconstructive surgery in cases of symptom-producing arteriosclerosis in the lower limbs. As an alternative, indirect Doppler ultrasonic examination has been employed but does not appear...

  19. Reconciling inverse-Compton Doppler factors with variability Doppler factors in blazar jets

    Science.gov (United States)

    Liodakis, I.; Zezas, A.; Angelakis, E.; Hovatta, T.; Pavlidou, V.

    2017-06-01

    Context. Blazar population models have shown that the inverse-Compton and variability Doppler factor estimates yield consistent results at the population level for flat spectrum radio quasars (FSRQs). The two methods, however, are inconsistent when compared on a source-by-source basis. Aims: In this work, we attempt to understand the source of the discrepancy by tracing the potential sources of systematic and statistical error for the inverse-Compton Doppler factors. By eliminating these sources of error, we provide stronger constrains on the value of the Doppler factor in blazar jets. Methods: We re-estimate the inverse-Compton Doppler factor for 11 sources that meet certain criteria for their synchrotron peak frequency and the availability of Doppler factor estimates in the literature. We compare these estimates with the average of two different estimates of the variability Doppler factor obtained using various datasets and methodologies to identify any discrepancies and, in each case, trace their sources in the methodology or assumptions adopted. Results: We identify three significant sources of error for the inverse-Compton Doppler factors: a) contamination of the X-ray flux by non-synchrotron self-Compton emission; b) radio observations at frequencies other than the synchrotron turnover frequency; c) non-simultaneity between radio and X-ray observations. We discuss key aspects in the correct application of the inverse-Compton method in light of these potential errors. We are able to constrain the Doppler factor of 3C 273, 3C 345, 3C 454.3, PKS 1510-089, and PKS 1633+382 effectively, since all available estimates from both methods converge to the same values for these five sources.

  20. [Heart rhythm abnormalities in middle-aged veteran elite athletes].

    Science.gov (United States)

    Sharashdze, N S; Pagava, Z T; Saatashvili, G A; Agladze, R A

    2008-06-01

    Disrrhythmia is frequent finding in high competitive athletes. Majority of heart rhythm abnormalities in athletes, suggested being benign, however, prognostic value of it is not yet well established. Purpose of the present study was to investigate heart rhythm and relationship of heart rhythm abnormalities with LV mass in veteran elite athletes. 30 veteran elite athletes (16 soccer players and 14 water-polo players) aged 30-50 were studied. They formed main group. >10 years of active sports activity and >5 years after competitive sports cessation. All athletes were symptom free. Control group consists of 30 age - matched sedentary healthy individuals. In all study subjects ambulatory 24 hour ECG was recorded and, LV mass, dimensions and function by ultrasound-Doppler technique was evaluated. LV mass by Devereux formula was calculated and indexed to body surface area. Student's t-test for continuous variables, Descriptive statistics and Fisher's exact test for categorical variables were used. A P-value of conductivity abnormalities as well as complex arrhythmias were more frequent findings in athletes as compared with healthy sedentary subjects. Heart Rhythm abnormalities were associated with enhanced LV mass in Veteran athletes. Hence, veteran elite athletes may be at increased risk of life threatening arrhythmias. However, prognostic value of heart rhythm disturbances in veteran athletes has to be studied.

  1. Prenatal diagnosis of single umbilical artery: determination of the absent side, associated anomalies, Doppler findings and perinatal outcome.

    Science.gov (United States)

    Geipel, A; Germer, U; Welp, T; Schwinger, E; Gembruch, U

    2000-02-01

    To determine the absent side of a single umbilical artery and its association with malformations and abnormal karyotypes. We prospectively studied 102 fetuses from 13 to 39 weeks of gestational age with a prenatally identified single umbilical artery. The absent side, pregnancy data, Doppler findings and the perinatal outcome were reviewed. (1) The left umbilical artery was absent in 71 (69.6%) and the right in 31 (30.4%) fetuses; (2) Single umbilical artery as an isolated finding occurred in 59 (57.8%) pregnancies and was not associated with aneuploidy. The mean gestational age at delivery in this group was 38.4 weeks and the mean birth weight was 3047 g. Six (10.2%) fetuses were small for gestational age, all of them with normal umbilical and uterine Doppler findings; and (3) Chromosomal abnormalities were diagnosed in 10 of 43 fetuses with single umbilical artery and congenital malformations. In nine of 10 fetuses with aneuploidy the left umbilical artery was not developed. Absence of the left artery occurred in 21 of 33 fetuses with sonographic anomalies and normal karyotype. Pathologic Doppler measurements of the umbilical artery were found in only one case of nonchromosomal abnormality. Our data suggest that in fetuses with single umbilical artery the absence of the left artery is more frequent than the absence of the right artery. The association with additional malformations seems to be equal on each side.

  2. Acute hemodialysis effects on doppler echocardiographic indices

    Directory of Open Access Journals (Sweden)

    Leila Abid

    2014-01-01

    Full Text Available Conventional echocardiographic (ECHO parameters of systolic and diastolic func-tion of the left ventricular (LV have been shown to be load dependent. However, the impact of pre-load reduction on tissue Doppler (TD parameters of LV function is incompletely understood. To evaluate the effect of a single hemodialysis (HD session on LV systolic and diastolic function using pulsed Doppler echocardiography and pulsed tissue Doppler imaging (TDI, we studied 81chronic HD patients (40 males; mean age 52.4 ± 16.4 years with these tools. ECHO parameters were obtained 30 min before and 30 min after HD. Fluid volume removed by HD was 1640 ± 730 cm [3] . HD led to reduction in LV end-diastolic volume (P <0.001, end-systolic volume (P <0.001, left atrium area (P <0.001, peak early (E-wave trans-mitral flow velocity (P <0.001, the ratio of early to late Doppler velocities of diastolic mitral inflow (P <0.001 and aortic time velocity integral (P <0.001. No significant change in peak S velocity of pulmonary vein flow after HD was noted. Early and late diastolic (E′ TDI velocities and the ratio of early to late TDI diastolic velocities (E′/A′ on the lateral side of the mitral annulus decreased signi-ficantly after HD (P = 0.013; P = 0.007 and P = 0.008, respectively. Velocity of flow progres-sion (Vp during diastole was not affected by pre-load reduction. Pulmonary artery systolic pressure and the diameter of the inferior vena cava decreased significantly (P <0.001 and P <0.001, respectively after HD. We conclude that most of the Doppler-derived indices of diastolic function are pre-load-dependent and velocity of flow progression was minimally affected by pre-load reduction in HD patients.

  3. Effects of Hemodialysis on Tei Index: Comparison between Flow Doppler and Tissue Doppler Imaging.

    Science.gov (United States)

    Gerede, Demet Menekse; Turhan, Sibel; Kaya, Cansin Tulunay; Ozcan, Ozgur Ulas; Goksuluk, Huseyin; Vurgun, Veysel Kutay; Dincer, Irem; Kutlay, Sim; Erturk, Sehsuvar; Erol, Cetin

    2015-10-01

    Myocardial performance index (MPI, Tei index) has been described as a noninvasive measurement of left ventricle (LV) function. Our aim was to investigate the influence of preload on the LV MPI obtained by pulsed-wave tissue Doppler imaging (PWTDI) and determined by flow Doppler waveforms in patients with end-stage chronic renal failure (CRF). The second aim of this study was to investigate the relationship between the Tei indices obtained by both methods. Eighty-four patients on regular hemodialysis (HD) treatment were included (mean age of 45.3 ± 14.5 years). Standard echocardiographic measurements, the Tei indices obtained by conventional flow Doppler and PWTDI methods, mitral inflow velocities, and mitral lateral annulus tissue Doppler velocities were measured immediately before and after hemodialysis. After HD, weight loss in patients was significantly revealed (predialysis 63.6 ± 13.3 kg; postdialysis 60.9 ± 13.0 kg; P Doppler method significantly increased, Tei index measuring by PWTDI did not change after HD. The conventional flow Doppler-derived LV Tei index is influenced by hemodialysis. However, PWTDI-derived LV Tei index is not influenced by hemodialysis. The loading status of a patient should be taken into account during the application of the Tei index to the evaluation of myocardial performance. © 2015, Wiley Periodicals, Inc.

  4. Placental mesenchymal dysplasia and intrauterine fetal growth restriction with doppler velocimetry alterations - a case report

    Directory of Open Access Journals (Sweden)

    Paula Vendruscolo Tozatti

    2014-06-01

    Full Text Available Placental mesenchymal dysplasia (PMD is a rare placental abnormality. We report a case of PMD associated with intrauterine growth restriction (IUGR, which was diagnosed by an ultrasound scan during the second trimester of pregnancy. A 36-year-old primiparous woman with signs of placental chorioangioma was referred to our hospital at the 23th gestational week. An ultrasonography revealed a small-for-gestational-age fetus with a large multicystic placenta. A serial Doppler sonographic assessment of umbilical and uterine artery blood flow showed a compromised fetus. A female, small-for-gestational-age baby was delivered by c-section at 28 weeks, and PMD was histopathologically confirmed.

  5. Diagnosis of neonatal hemochromatosis with MR imaging and duplex Doppler sonography

    Energy Technology Data Exchange (ETDEWEB)

    Oddone, M.; Toma, P. [Dept. of Radiology, G. Gaslini Children' s Research Hospital, Genoa (Italy); Bellini, C.; Bonacci, W.; Bartocci, M.; Serra, G. [Department of Pediatrics, Neonatal Intensive Care Unit, University of Genoa, G. Gaslini Children' s Research Hospital, Largo G. Gaslini, 5, I-16147 Genoa (Italy)

    1999-07-01

    Neonatal hemochromatosis is a rare congenital disorder which affects both fetuses and newborns. It is characterized by hepatocellular failure, often appearing on the first day of life in the form of coagulopathy, hypoalbuminemia, hypoglycemia, and jaundice. Most of the affected infants die early in life, and definitive diagnosis has often been made only by post-mortem evaluation. With the help of MRI, plus increasing awareness of the disorder, diagnosis is now often made early, even in utero. Duplex Doppler sonography does not provide information on siderosis but shows abnormalities in the liver or blood-flow patterns associated with liver disease. (orig.)

  6. Enteral tube feeding in adults.

    Science.gov (United States)

    Scott, R; Bowling, T E

    2015-03-01

    Enteral tube feeding is usually a relatively straightforward method of nutritional support, and should be facilitated by a multiprofessional team. For short-term use (tube is indicated but if longer term feeding is required then a gastrostomy is appropriate, usually inserted endoscopically (a percutaneous endoscopic gastrostomy tube). The most common serious complication of a nasogastric tube is not identifying a misplaced tube within the lungs: there are clear recommendations from the National Patient Safety Agency as to how to check tube placement. Nasojejunal tubes are required in patients with gastroparesis. Tube blockage is common and is prevented by careful and regular flushing. Diarrhoea is the most complication of feeding and is often related to other medication. Clinicians need an algorithm for systematically dealing with such a problem. Refeeding syndrome may occur in malnourished patients and is characterised by low levels of potassium, phosphate, and/or magnesium, as well as disorders of water and salt balance. Identifying the at-risk patient with careful monitoring is crucial.

  7. CERN openlab enters new phase

    CERN Document Server

    Katarina Anthony

    2012-01-01

    The newest phase of CERN’s openlab framework was inaugurated this week during a meeting of the openlab partners. This phase will last three years and will bring together existing openlab partners and a new contributor: Huawei.   Group picture taken at the first CERN openlab IV annual Board of Sponsors meeting, in the presence of the CERN Director-General, the partners and the openlab team members. © Fons Rademakers (CERN Photo Club). Eleven years ago, the creation of the CERN openlab created a long-term link between industrial partners and the Organization. Its framework has allowed industry to carry out large-scale IT research and development in an open atmosphere – an “Open Lab”, if you will. For CERN, openlab has contributed to giving the computing centre and, more broadly, the LHC community, the opportunity to ensure that the next generation of services and products is suitable to their needs. Now entering its fourth phase, openlab will ...

  8. Extending the enteric nervous system.

    Science.gov (United States)

    Sbarbati, Andrea; Osculati, Francesco

    2007-08-01

    The work reviews the evidence suggesting that lingual components of the autonomic system may be considered the most rostral portion of the enteric nervous system (ENS) defining the concept of lingual ENS (LENS). The LENS is not dissimilar from the more distally located portions of the ENS, however, it is characterized by a massive sensory input generated by collaterals of gustatory and trigeminal fibers. The different neuronal subpopulations that compose the LENS operate reflexes involved in regulation of secretion and vasomotility. Systemic reflexes on the digestive and respiratory apparatus are operated by means of neural connections through the pharynx or larynx. The LENS can modulate the activity of distally located organs by means of the annexed glands.The LENS seems therefore to be a "chemical eye" located at the beginning of the digestive apparatus which analyses the foods before their ingestion and diffuses this information distally. The definition of the LENS supports the concept of an elevated degree of autonomy in the ENS and puts in a new light the role of the gustatory system in modulation of the digestive functions. For its characteristics, the LENS appears to be an ideal model to study the elementary connectivity of the ENS.

  9. Cardiac abnormalities assessed by non-invasive techniques in patients with newly diagnosed idiopathic inflammatory myopathies

    DEFF Research Database (Denmark)

    Diederichsen, Louise Pyndt; Simonsen, Jane Angel; Diederichsen, Axel Cosmus Pyndt

    2015-01-01

    , cardiac troponin-I (TnI), electrocardiogram (standard 12-lead and 48-h Holter monitoring), echocardiography with tissue Doppler measures, cardiac magnetic resonance (CMR) imaging with T2 mapping and semi-quantitative (99m)technetium pyrophosphate ((99m)Tc-PYP) scintigraphy. RESULTS: Dyspnoea was present....... The myocardial (99m)Tc-PYP uptake and CMR results differed between patients and controls, albeit not with statistical significance. Overall, cardiac abnormalities were demonstrated in 9 (64%) of the patients versus 2 (14%) of the controls (p=0.02). CONCLUSIONS: Cardiac abnormalities assessed by TnI, ECG...

  10. Abnormal uterine bleeding.

    Science.gov (United States)

    Whitaker, Lucy; Critchley, Hilary O D

    2016-07-01

    Abnormal uterine bleeding (AUB) is a common and debilitating condition with high direct and indirect costs. AUB frequently co-exists with fibroids, but the relationship between the two remains incompletely understood and in many women the identification of fibroids may be incidental to a menstrual bleeding complaint. A structured approach for establishing the cause using the Fédération International de Gynécologie et d'Obstétrique (FIGO) PALM-COEIN (Polyp, Adenomyosis, Leiomyoma, Malignancy (and hyperplasia), Coagulopathy, Ovulatory disorders, Endometrial, Iatrogenic and Not otherwise classified) classification system will facilitate accurate diagnosis and inform treatment options. Office hysteroscopy and increasing sophisticated imaging will assist provision of robust evidence for the underlying cause. Increased availability of medical options has expanded the choice for women and many will no longer need to recourse to potentially complicated surgery. Treatment must remain individualised and encompass the impact of pressure symptoms, desire for retention of fertility and contraceptive needs, as well as address the management of AUB in order to achieve improved quality of life. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  11. Evaluation of nail abnormalities.

    Science.gov (United States)

    Tully, Amber S; Trayes, Kathryn P; Studdiford, James S

    2012-04-15

    Knowledge of the anatomy and function of the nail apparatus is essential when performing the physical examination. Inspection may reveal localized nail abnormalities that should be treated, or may provide clues to an underlying systemic disease that requires further workup. Excessive keratinaceous material under the nail bed in a distal and lateral distribution should prompt an evaluation for onychomycosis. Onychomycosis may be diagnosed through potassium hydroxide examination of scrapings. If potassium hydroxide testing is negative for the condition, a nail culture or nail plate biopsy should be performed. A proliferating, erythematous, disruptive mass in the nail bed should be carefully evaluated for underlying squamous cell carcinoma. Longitudinal melanonychia (vertical nail bands) must be differentiated from subungual melanomas, which account for 50 percent of melanomas in persons with dark skin. Dystrophic longitudinal ridges and subungual hematomas are local conditions caused by trauma. Edema and erythema of the proximal and lateral nail folds are hallmark features of acute and chronic paronychia. Clubbing may suggest an underlying disease such as cirrhosis, chronic obstructive pulmonary disease, or celiac sprue. Koilonychia (spoon nail) is commonly associated with iron deficiency anemia. Splinter hemorrhages may herald endocarditis, although other causes should be considered. Beau lines can mark the onset of a severe underlying illness, whereas Muehrcke lines are associated with hypoalbuminemia. A pincer nail deformity is inherited or acquired and can be associated with beta-blocker use, psoriasis, onychomycosis, tumors of the nail apparatus, systemic lupus erythematosus, Kawasaki disease, and malignancy.

  12. Communication and abnormal behaviour.

    Science.gov (United States)

    Crown, S

    1979-01-01

    In this paper the similarities between normal and abnormal behaviour are emphasized and selected aspects of communication, normal and aberrant, between persons are explored. Communication in a social system may be verbal or non-verbal: one person's actions cause a response in another person. This response may be cognitive, behavioural or physiological. Communication may be approached through the individual, the social situation or social interaction. Psychoanalysis approaches the individual in terms of the coded communications of psychoneurotic symptoms or psychotic behaviour; the humanist-existential approach is concerned more with emotional expression. Both approaches emphasize the development of individual identity. The interaction between persons and their social background is stressed. Relevant are sociological concepts such as illness behaviour, stigma, labelling, institutionalization and compliance. Two approaches to social interactions are considered: the gamesplaying metaphor, e.g. back pain as a psychosocial manipulation--the 'pain game'; and the 'spiral of reciprocal perspectives' which emphasizes the interactional complexities of social perceptions. Communicatory aspects of psychological treatments are noted: learning a particular metaphor such as 'resolution' of the problem (psychotherapy), learning more 'rewarding' behaviour (learning theory) or learning authenticity or self-actualization (humanist-existential).

  13. Power and color Doppler ultrasound settings for inflammatory flow

    DEFF Research Database (Denmark)

    Torp-Pedersen, Søren; Christensen, Robin; Szkudlarek, Marcin

    2015-01-01

    OBJECTIVE: To determine how settings for power and color Doppler ultrasound sensitivity vary on different high- and intermediate-range ultrasound machines and to evaluate the impact of these changes on Doppler scoring of inflamed joints. METHODS: Six different types of ultrasound machines were used....... On each machine, the factory setting for superficial musculoskeletal scanning was used unchanged for both color and power Doppler modalities. The settings were then adjusted for increased Doppler sensitivity, and these settings were designated study settings. Eleven patients with rheumatoid arthritis (RA......) with wrist involvement were scanned on the 6 machines, each with 4 settings, generating 264 Doppler images for scoring and color quantification. Doppler sensitivity was measured with a quantitative assessment of Doppler activity: color fraction. Higher color fraction indicated higher sensitivity. RESULTS...

  14. [Enteral feeding tubes for critically ill patients].

    Science.gov (United States)

    Braun, J; Bein, T; Wiese, C H R; Graf, B M; Zausig, Y A

    2011-04-01

    The use of enteral feeding tubes is an important part of early enteral feeding in intensive care medicine. In other faculties with non-critically ill patients, such as (oncologic) surgery, neurology, paediatrics or even in palliative care medicine feeding tubes are used under various circumstances as a temporary or definite solution. The advantage of enteral feeding tubes is the almost physiologic administration of nutrition, liquids and medication. Enteral nutrition is thought to be associated with a reduced infection rate, increased mucosal function, improved immunologic function, reduced length of hospital stay and reduced costs. However, the insertion and use of feeding tubes is potentially dangerous and may be associated with life-threatening complications (bleeding, perforation, peritonitis, etc.). Therefore, the following article will give a summary of the different types of enteral feeding tubes and their range of application. Additionally, a critical look on indication and contraindication is given as well as how to insert an enteral feeding tube.

  15. Superharmonic microbubble Doppler effect in ultrasound therapy

    Science.gov (United States)

    Pouliopoulos, Antonios N; Choi, James J

    2016-01-01

    Abstract The introduction of microbubbles in focused ultrasound therapies has enabled a diverse range of non-invasive technologies: sonoporation to deliver drugs into cells, sonothrombolysis to dissolve blood clots, and blood-brain barrier opening to deliver drugs into the brain. Current methods for passively monitoring the microbubble dynamics responsible for these therapeutic effects can identify the cavitation position by passive acoustic mapping and cavitation mode by spectral analysis. Here, we introduce a new feature that can be monitored: microbubble effective velocity. Previous studies have shown that echoes from short imaging pulses had a Doppler shift that was produced by the movement of microbubbles. Therapeutic pulses are longer (>1 000 cycles) and thus produce a larger alteration of microbubble distribution due to primary and secondary acoustic radiation force effects which cannot be monitored using pulse-echo techniques. In our experiments, we captured and analyzed the Doppler shift during long therapeutic pulses using a passive cavitation detector. A population of microbubbles (5  ×  104–5  ×  107 microbubbles ml−1) was embedded in a vessel (inner diameter: 4 mm) and sonicated using a 0.5 MHz focused ultrasound transducer (peak-rarefactional pressure: 75–366 kPa, pulse length: 50 000 cycles or 100 ms) within a water tank. Microbubble acoustic emissions were captured with a coaxially aligned 7.5 MHz passive cavitation detector and spectrally analyzed to measure the Doppler shift for multiple harmonics above the 10th harmonic (i.e. superharmonics). A Doppler shift was observed on the order of tens of kHz with respect to the primary superharmonic peak and is due to the axial movement of the microbubbles. The position, amplitude and width of the Doppler peaks depended on the acoustic pressure and the microbubble concentration. Higher pressures increased the effective velocity of the microbubbles up to 3 m s−1, prior to

  16. Superharmonic microbubble Doppler effect in ultrasound therapy.

    Science.gov (United States)

    Pouliopoulos, Antonios N; Choi, James J

    2016-08-21

    The introduction of microbubbles in focused ultrasound therapies has enabled a diverse range of non-invasive technologies: sonoporation to deliver drugs into cells, sonothrombolysis to dissolve blood clots, and blood-brain barrier opening to deliver drugs into the brain. Current methods for passively monitoring the microbubble dynamics responsible for these therapeutic effects can identify the cavitation position by passive acoustic mapping and cavitation mode by spectral analysis. Here, we introduce a new feature that can be monitored: microbubble effective velocity. Previous studies have shown that echoes from short imaging pulses had a Doppler shift that was produced by the movement of microbubbles. Therapeutic pulses are longer (>1 000 cycles) and thus produce a larger alteration of microbubble distribution due to primary and secondary acoustic radiation force effects which cannot be monitored using pulse-echo techniques. In our experiments, we captured and analyzed the Doppler shift during long therapeutic pulses using a passive cavitation detector. A population of microbubbles (5  ×  10(4)-5  ×  10(7) microbubbles ml(-1)) was embedded in a vessel (inner diameter: 4 mm) and sonicated using a 0.5 MHz focused ultrasound transducer (peak-rarefactional pressure: 75-366 kPa, pulse length: 50 000 cycles or 100 ms) within a water tank. Microbubble acoustic emissions were captured with a coaxially aligned 7.5 MHz passive cavitation detector and spectrally analyzed to measure the Doppler shift for multiple harmonics above the 10th harmonic (i.e. superharmonics). A Doppler shift was observed on the order of tens of kHz with respect to the primary superharmonic peak and is due to the axial movement of the microbubbles. The position, amplitude and width of the Doppler peaks depended on the acoustic pressure and the microbubble concentration. Higher pressures increased the effective velocity of the microbubbles up to 3 m s(-1), prior to the onset

  17. Syndromic diarrhea/Tricho-hepato-enteric syndrome

    Science.gov (United States)

    2013-01-01

    Abstract Syndromic diarrhea/Tricho-hepato-enteric syndrome (SD/THE) is a rare and severe bowel disorder caused by mutation in SKIV2L or in TTC37, 2 genes encoding subunits of the putative human SKI complex. The estimated prevalence is 1/1,000,000 births and the transmission is autosomal recessive. The classical form is characterized by 5 clinical signs: intractable diarrhea of infancy beginning in the first month of life, usually leading to failure to thrive and requiring parenteral nutrition; facial dysmorphism characterised by prominent forehead and cheeks, broad nasal root and hypertelorism; hair abnormalities described as woolly and easily removable; immune disorders resulting from defective antibody production; intrauterine growth restriction. The aetiology is a defect in TTC37, a TPR containing protein, or in the RNA helicase SKIV2L, both constituting the putative human ski complex. The ski complex is a heterotetrameric cofactor of the cytoplasmic RNA exosome which ensures aberrants mRNAs decay. The diagnosis SD/THE is initially based on clinical findings and confirmed by direct sequencing of TTC37 and SKIV2L. Differential diagnosis with the other causes of intractable diarrhea is easily performed by pathologic investigations. During their clinical course, most of the children require parenteral nutrition and often immunoglobulin supplementation. With time, some of them can be weaned off parenteral nutrition and immunoglobulin supplementation. The prognosis depends on the management and is largely related to the occurrence of parenteral nutrition complications or infections. Even with optimal management, most of the children seem to experience failure to thrive and final short stature. Mild mental retardation is observed in half of the cases. Abstract in French Les diarrhées syndromiques ou syndrome tricho-hepato-enterique (SD/THE) sont un syndrome rare et sévère dont l’incidence est estimée à 1 cas pour 1 million de naissances et la transmission

  18. Syndromic diarrhea/Tricho-hepato-enteric syndrome

    Directory of Open Access Journals (Sweden)

    Fabre Alexandre

    2013-01-01

    Full Text Available Abstract Syndromic diarrhea/Tricho-hepato-enteric syndrome (SD/THE is a rare and severe bowel disorder caused by mutation in SKIV2L or in TTC37, 2 genes encoding subunits of the putative human SKI complex. The estimated prevalence is 1/1,000,000 births and the transmission is autosomal recessive. The classical form is characterized by 5 clinical signs: intractable diarrhea of infancy beginning in the first month of life, usually leading to failure to thrive and requiring parenteral nutrition; facial dysmorphism characterised by prominent forehead and cheeks, broad nasal root and hypertelorism; hair abnormalities described as woolly and easily removable; immune disorders resulting from defective antibody production; intrauterine growth restriction. The aetiology is a defect in TTC37, a TPR containing protein, or in the RNA helicase SKIV2L, both constituting the putative human ski complex. The ski complex is a heterotetrameric cofactor of the cytoplasmic RNA exosome which ensures aberrants mRNAs decay. The diagnosis SD/THE is initially based on clinical findings and confirmed by direct sequencing of TTC37 and SKIV2L. Differential diagnosis with the other causes of intractable diarrhea is easily performed by pathologic investigations. During their clinical course, most of the children require parenteral nutrition and often immunoglobulin supplementation. With time, some of them can be weaned off parenteral nutrition and immunoglobulin supplementation. The prognosis depends on the management and is largely related to the occurrence of parenteral nutrition complications or infections. Even with optimal management, most of the children seem to experience failure to thrive and final short stature. Mild mental retardation is observed in half of the cases. Abstract in French Les diarrhées syndromiques ou syndrome tricho-hepato-enterique (SD/THE sont un syndrome rare et sévère dont l’incidence est estimée à 1 cas pour 1 million de naissances et la

  19. Application and Preparation of Enteric Coating Materials

    Science.gov (United States)

    Zhou, M. M.; Wang, L.; Zhang, X. L.; Zhou, H. J.; Chen, X. Q.; Li, Y. T.; Yang, S. L.

    2017-02-01

    In this paper, polymethacrylate enteric coated materials based on the equal mass of methyl acrylic acid and ethyl acrylate as the main raw materials were synthesized through emulsion polymerization. Omeprazole Enteric-coated Capsules were prepared by the fluidized bed coating technology using above materials as enteric layer and in vitro enteric test was considered according to standard. The results showed that the material had good coverage in the surface of omeprazole isolated pellets, excellent acid resistance in artificial gastric acid environment, and reached the disintegration effect in the buffer solution of 20min. Moreover the drug release reached 88.2% and had excellent long-term storage.

  20. Clinical application of transcranial Doppler ultrasonography in premature, very-low-birth-weight neonates

    Energy Technology Data Exchange (ETDEWEB)

    Gabriel, Marta Lucia [Fundacao Faculdade Regional de Medicina (FUNFARME), Sao Jose do Rio Preto, SP (Brazil). Hospital de Base; Piatto, Vania Belintani [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil); Souza, Antonio Soares, E-mail: depimagem@famerp.b [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Dept. de Diagnostico por Imagem

    2010-07-15

    Objective: the present study was aimed at analyzing the value of the early diagnosis of hemodynamic changes in hemorrhages and hypoxic-ischemic events in premature, very-low-birth-weight neonates through the evaluation of images and resistance index measurement by means of transcranial Doppler ultrasonography. Materials and methods: fifty premature, very-low-birth-weight neonates were submitted to transcranial Doppler ultrasonography with sequential transfontanellar and transtemporal techniques. Results: cerebral abnormalities were detected in 32% of the neonates (22% with intracranial hemorrhage, 8% with periventricular leukomalacia, and 2% with toxoplasmosis). Among the 34 cases (68%) of neonates in whom no brain lesion was detected at transcranial Doppler ultrasonography, 18 (53%) presented changes in the resistance index. Such resistance index varied according to the time of the examination. Conclusion: there is a correlation between the presence of cerebral hemodynamic changes demonstrated by resistance index measurements and the subsequent development of hemorrhages and hypoxic-ischemic lesions. Although not being a death predictor, changes in the resistance index are associated with the severity of the clinical conditions in preterm, very-low-birth-weight neonates. (author)

  1. Doppler ultrasonography in living donor liver transplantation recipients: Intra- and post-operative vascular complications

    Science.gov (United States)

    Abdelaziz, Omar; Attia, Hussein

    2016-01-01

    Living-donor liver transplantation has provided a solution to the severe lack of cadaver grafts for the replacement of liver afflicted with end-stage cirrhosis, fulminant disease, or inborn errors of metabolism. Vascular complications remain the most serious complications and a common cause for graft failure after hepatic transplantation. Doppler ultrasound remains the primary radiological imaging modality for the diagnosis of such complications. This article presents a brief review of intra- and post-operative living donor liver transplantation anatomy and a synopsis of the role of ultrasonography and color Doppler in evaluating the graft vascular haemodynamics both during surgery and post-operatively in accurately defining the early vascular complications. Intra-operative ultrasonography of the liver graft provides the surgeon with useful real-time diagnostic and staging information that may result in an alteration in the planned surgical approach and corrections of surgical complications during the procedure of vascular anastomoses. The relevant intra-operative anatomy and the spectrum of normal and abnormal findings are described. Ultrasonography and color Doppler also provides the clinicians and surgeons early post-operative potential developmental complications that may occur during hospital stay. Early detection and thus early problem solving can make the difference between graft survival and failure. PMID:27468207

  2. Doppler ultrasonography in living donor liver transplantation recipients: Intra- and post-operative vascular complications.

    Science.gov (United States)

    Abdelaziz, Omar; Attia, Hussein

    2016-07-21

    Living-donor liver transplantation has provided a solution to the severe lack of cadaver grafts for the replacement of liver afflicted with end-stage cirrhosis, fulminant disease, or inborn errors of metabolism. Vascular complications remain the most serious complications and a common cause for graft failure after hepatic transplantation. Doppler ultrasound remains the primary radiological imaging modality for the diagnosis of such complications. This article presents a brief review of intra- and post-operative living donor liver transplantation anatomy and a synopsis of the role of ultrasonography and color Doppler in evaluating the graft vascular haemodynamics both during surgery and post-operatively in accurately defining the early vascular complications. Intra-operative ultrasonography of the liver graft provides the surgeon with useful real-time diagnostic and staging information that may result in an alteration in the planned surgical approach and corrections of surgical complications during the procedure of vascular anastomoses. The relevant intra-operative anatomy and the spectrum of normal and abnormal findings are described. Ultrasonography and color Doppler also provides the clinicians and surgeons early post-operative potential developmental complications that may occur during hospital stay. Early detection and thus early problem solving can make the difference between graft survival and failure.

  3. Cardiotocographic and Doppler ultrasonographic findings in a fetus with brain death syndrome.

    Science.gov (United States)

    Chen, Yi-Ting; Hsu, Shih-Tien; Tseng, Jenn-Jhy; Chen, Wei-Chih; Ho, Esther Shih-Chu; Chou, Min-Min

    2006-09-01

    The diagnosis of brain death syndrome by cardiotocography (CTG) and Doppler ultrasonography (US) is reported in a fetus at 35 weeks of gestation. A 23-year-old, gravida 2, para 0, woman was referred to our hospital because of the absence of fetal movements. CTG showed fixed fetal heart rate (FHR) pattern. A detailed Doppler US examination of the fetus showed extensive cystic lesions of both cerebral hemispheres, polyhydramnios, total absence of neuromuscular parameters of biophysical profile (BPP) and the cessation of cerebral blood flow. Umbilical cord artery blood gas analysis showed pH 7.3, PaO2 30 mmHg and PaCO2 35 mmHg. A floppy male infant weighing 2,450 g was delivered vaginally at 36 weeks of gestation and the Apgar scores were 1 and 1 at 5 and 10 minutes, respectively. The neonate died 2 days after delivery. Postmortem examination of the brain showed diffuse, anoxic changes with multicystic encephalomalacia in both hemispheres and the brain stem. No other maternal or placental abnormalities were seen. The possibility of intrauterine brain death should be considered in all cases of prolonged fixed FHR pattern, accompanied by absence of neuromuscular parameters of BPP, polyhydramnios and demonstrated cessation of cerebral blood flow by Doppler US. Increased awareness of this event may prevent unnecessary emergency cesarean section.

  4. Color Doppler US of the penis

    Energy Technology Data Exchange (ETDEWEB)

    Bertolotto, Michele (ed.) [Trieste Univ. Ospedale di Cattinara (Italy). Dept. Radiology

    2008-07-01

    This book provides a comprehensive reference and practical guide on the application of US to penile diseases and conditions. After introductory chapters on technical requirements and penile anatomy, subsequent chapters offer a systematic overview of the diverse applications of color Doppler US. The topics covered include erectile dysfunction, Peyronie's disease, priapism, trauma, tumors, the postoperative penis, inflammation, and fibrosis. Each topic is introduced by a clinical overview with the purpose of clarifying the problems and elucidating what the urologist may expect from color Doppler US. Thereafter, performance of the US study is explained and the pathological anatomy reviewed. High-quality images obtained with high-end US equipment are included. Each chapter also contains a section on the diagnostic information provided by other imaging modalities, and in particular MRI. (orig.)

  5. Transcranial Doppler sonography in familial hemiplegic migraine

    Energy Technology Data Exchange (ETDEWEB)

    Pierelli, F.; Pauri, F.; Cupini, L.M.; Fiermonte, G.; Rizzo, P.A. (Universita la Sapienza, Roma (Italy))

    1991-02-01

    A patient affected by familial hemiplegic migraine underwent transcranial Doppler sonography twice: the first during a spontaneous attack with right hemiparesis and aphasia, the second during a headachefree period. During the attack the following haemodynamic changes were seen: (a) bilateral increase in the middle cerebral artery and anterior cerebral artery blood flow velocities (this increase was more pronounced on the left side), (b) decreased systo-diastolic ratio and pulsatility index on the right side, (c) increased systo-diastolic ratio and pulsatility index on the left side. The results indicate that during the attack in this familial hemiplegic migraine patient, a diffuse vasoconstriction of the basal cerebral arteries developed. Moreover, transcranial Doppler sonography data suggest that a prolonged vasoconstriction of the peripheral arterioles could play a role in determining the neurological symptoms in this syndrome. 13 refs., 1 figs., 1 tab.

  6. [New home enteral nutrition via jejunostomy using semi-solid enteral formula].

    Science.gov (United States)

    Ogasawara, Mihoko; Makishima, Junko; Maruyama, Makishima Michio

    2014-12-01

    Home enteral nutrition via jejunostomy requires considerable time for infusion to the patients. A new method using semisolid enteral formula dramatically reduces the time of infusion. This method makes use of pectin and liquid enteral formula. The authors applied this method in two patients with total gastrectomy being given enteral nutrition at home. There were no complications such as diarrhea or abdominal pain. This new method of home enteral nutrition could enhance the patients' quality of life (QOL) by reducing the time of infusion of enteral nutrition.

  7. Diagnostic evaluation of uterine artery Doppler sonography for the prediction of adverse pregnancy outcomes

    Directory of Open Access Journals (Sweden)

    Mojgan Barati

    2014-01-01

    Full Text Available Background : Increased impedance to flow in the uterine arteries assessed by value of the Doppler is associated with adverse pregnancy outcomes, especially pre-eclampsia. We investigated the predictive value of a uterine artery Doppler in the identification of adverse pregnancy outcomes such as ′pre-eclampsia′ and ′small fetus for gestational age′ (SGA. Materials and Methods: Three hundred and seventy-nine women, with singleton pregnancy, between 18 and 40 years of age, without risk factors, randomly underwent Doppler interrogation of the uterine arteries, between 16-22 weeks of gestation. Those who had a mean pulsatility index (PI of >1.45 were considered to have an abnormal result, and were evaluated and compared with those who had normal results for adverse pregnancy outcomes, including pre-eclampsia and small for gestational age. The relationship between the variables was assessed with the use of the chi-square test. Results : There were 17 cases (4.5% of abnormal uterine artery Doppler results and 15 of them (88.2% developed pre-eclampsia and four cases (23.5% had neonates small for gestational age. For predicting pre-eclampsia, the mean uterine artery PI had to be >1.45, had to have a specificity of 95.5% (95% CI, 70-92%, a sensitivity of 79% (95% CI, 43-82%, a negative predictive value (NPV of 98.9% (95% CI, 72-96%, and a positive predictive value (PPV of 88.2% (95% CI, 68-98%. In the case of ′small for gestational age′ it had to have a specificity of 96.5% (95% CI, 42-68%, a sensitivity of 57% (95% CI, 53-76%, an NPV of 99.2% (95% CI, 70-92%, and a PPV of 23.5% (95% CI, 30-72%. Conclusion : Uterine artery Doppler evaluation at 16-22 weeks of gestation might be an appropriate tool for identifying pregnancies that may be at an increased risk for development of pre-eclampsia and small fetus for gestational age.

  8. Colour Doppler ultrasound of the penis

    Energy Technology Data Exchange (ETDEWEB)

    Wilkins, C.J.; Sriprasad, S.; Sidhu, P.S. E-mail: paulsidhu@compuserve.com

    2003-07-01

    Because it is a superficial structure, the penis is ideally suited to ultrasound imaging. A number of disease processes, including Peyronie's disease, penile fractures and penile tumours, are clearly visualized with ultrasound. An assessment of priapism can also be made using spectral Doppler waveform technology. Furthermore, dynamic assessment of cavernosal arterial changes after pharmaco-stimulation allows diagnosis of arterial and venogenic causes for impotence. This pictorial review illustrates the range of diseases encountered with ultrasound of the penis.

  9. Doppler Lidar Wind Value-Added Product

    Energy Technology Data Exchange (ETDEWEB)

    Newsom, R. K. [DOE ARM Climate Research Facility, Washington, DC (United States); Sivaraman, C. [DOE ARM Climate Research Facility, Washington, DC (United States); Shippert, T. R. [DOE ARM Climate Research Facility, Washington, DC (United States); Riihimaki, L. D. [DOE ARM Climate Research Facility, Washington, DC (United States)

    2015-07-01

    Wind speed and direction, together with pressure, temperature, and relative humidity, are the most fundamental atmospheric state parameters. Accurate measurement of these parameters is crucial for numerical weather prediction. Vertically resolved wind measurements in the atmospheric boundary layer are particularly important for modeling pollutant and aerosol transport. Raw data from a scanning coherent Doppler lidar system can be processed to generate accurate height-resolved measurements of wind speed and direction in the atmospheric boundary layer.

  10. Measuring retinal blood flow in rats using Doppler optical coherence tomography without knowing eyeball axial length

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Wenzhong; Yi, Ji; Chen, Siyu [Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208 (United States); Jiao, Shuliang [Department of Biomedical Engineering, Florida International University, Miami, Florida 33174 (United States); Zhang, Hao F., E-mail: hfzhang@northwestern.edu [Department of Biomedical Engineering, Northwestern University, Evanston, Illinois 60208 and Department of Ophthalmology, Northwestern University, Chicago, Illinois 60611 (United States)

    2015-09-15

    Purpose: Doppler optical coherence tomography (OCT) is widely used for measuring retinal blood flow. Existing Doppler OCT methods require the eyeball axial length, in which empirical values are usually used. However, variations in the axial length can create a bias unaccounted for in the retinal blood flow measurement. The authors plan to develop a Doppler OCT method that can measure the total retinal blood flow rate without requiring the eyeball axial length. Methods: The authors measured the retinal blood flow rate using a dual-ring scanning protocol. The small and large scanning rings entered the eye at different incident angles (small ring: 4°; large ring: 6°), focused on different locations on the retina, and detected the projected velocities/phase shifts along the probing beams. The authors calculated the ratio of the projected velocities between the two rings, and then used this ratio to estimate absolute flow velocity. The authors tested this method in both Intralipid phantoms and in vivo rats. Results: In the Intralipid flow phantom experiments, the preset and measured flow rates were consistent with the coefficient of determination as 0.97. Linear fitting between preset and measured flow rates determined the fitting slope as 1.07 and the intercept as −0.28. In in vivo rat experiments, the measured average total retinal blood flow was 7.02 ± 0.31μl/min among four wild-type rats. The authors’ measured flow rates were consistent with results in the literature. Conclusions: By using a dual-ring scanning protocol with carefully controlled incident angle difference between the two scanning rings in Doppler OCT, the authors demonstrated that it is feasible to measure the absolute retinal blood flow without knowing the eyeball axial length.

  11. Doppler sonographic findings in testicular microlithiasis

    Directory of Open Access Journals (Sweden)

    Selim Serter

    2008-08-01

    Full Text Available OBJECTIVE: The aim of this prospective study was to compare the resistive index (RI values, which is a parameter of testicular parenchymal perfusion, in testicular microlithiasis (TM cases and normal cases. MATERIALS AND METHODS: 2179 volunteers, all healthy men (17-42 years of age from the Annual Army Reserve Officer Training Corps training camp were included in the study. A screening scrotal ultrasound was performed and all men diagnosed with TM underwent a scrotal Doppler ultrasonography scan (US. US examinations were performed for subjects with TM and without TM as a control group and RI was determined. RESULTS: 53 men with TM were identified in the 2179 US. Spectral Doppler examination was applied to 50 randomly selected cases (100 testicles without TM and 92 testicles with TM, 39 cases (78 testicles with bilateral and 14 cases with unilateral involvement. However, 48 normal testicles (17 bilateral and 14 unilateral and 47 testicles with TM (15 bilateral and 17 unilateral, 10 of which were cases with bilateral TM where flow from the centripetal artery could be obtained and analyzed were included in the statistical analysis for resistive indices. There was no significant difference regarding the RI and spectral examinations between subjects with and without TM. An interesting finding was the twinkling artifact observed in three cases. CONCLUSION: Microliths did not alter the RI values and thus had no influence on testicular perfusion on Doppler US examination.

  12. Doppler Lidar for Wind Measurements on Venus

    Science.gov (United States)

    Singh, Upendra N.; Emmitt, George D.; Yu, Jirong; Kavaya, Michael J.

    2010-01-01

    NASA Langley Research Center has a long history of developing 2-micron laser transmitter for wind sensing. With support from NASA Laser Risk Reduction Program (LRRP) and Instrument Incubator Program (IIP), NASA Langley Research Center has developed a state-of-the-art compact lidar transceiver for a pulsed coherent Doppler lidar system for wind measurement. The transmitter portion of the transceiver employs the high-pulse-energy, Ho:Tm:LuLiF, partially conductively cooled laser technology developed at NASA Langley. The transceiver is capable of 250 mJ pulses at 10 Hz. It is very similar to the technology envisioned for coherent Doppler lidar wind measurements from Earth and Mars orbit. The transceiver is coupled to the large optics and data acquisition system in the NASA Langley VALIDAR mobile trailer. The large optics consists of a 15-cm off-axis beam expanding telescope, and a full-hemispheric scanner. Vertical and horizontal vector winds are measured, as well as relative backscatter. The data acquisition system employs frequency domain velocity estimation and pulse accumulation. It permits real-time display of the processed winds and archival of all data. This lidar system was recently deployed at Howard University facility in Beltsville, Mary-land, along with other wind lidar systems. Coherent Doppler wind lidar ground-based wind measurements and comparisons with other sensors will be presented. A simulation and data product for wind measurement at Venus will be presented.

  13. The importance of community screening of asymptomatic elderly for peripheral arterial disease by Doppler ultrasound and ankle-brachial index.

    Science.gov (United States)

    Keven, Ayşe; Durmaz, Mehmet Sedat

    2017-12-01

    Peripheral arterial disease is an atherosclerotic disease characterized by an increase in morbidity and mortality. For these reasons early diagnosis of peripheral arterial disease is important. Ankle-brachial systolic pressure index measurement is frequently used in screening studies. Evaluating waveforms of distal lower extremities with Doppler ultrasound can be used as a screening program and provides more accurate information on peripheral arterial disease. We investigate the prevalence of peripheral arterial disease, compare the efficacy of Doppler ultrasound evaluation of distal lower extremity waveforms and ankle-brachial systolic pressure index measurement in screening programs, and discuss the importance of early diagnosis of asymptomatic cases. A total of 457 patients over the age of 65 (between 65 and 94, mean age: 71.4) including 270 males and 187 females were examined with Doppler ultrasound, had ankle-brachial systolic pressure index measurement taken and were screened for peripheral arterial disease. The correlation between Doppler ultrasound findings and ankle-brachial systolic pressure index was examined. According to the Doppler ultrasound findings, in the aortoiliac ( r = 0.648) and femoropopliteal ( r = 0.564) area, there is a medium level of correlation between severe stenosis and occlusions and a low ankle-brachial systolic pressure index value, and a low level of correlation between such abnormalities in the tibioperoneal region ( r = 0.116) and a low ankle-brachial systolic pressure index value. Therefore, while the sensitivity of ankle-brachial systolic pressure index increases in proximal stenosis, it decreases in distal stenosis. Despite the fact that ankle-brachial systolic pressure index is a diagnostic test commonly used in screening studies, evaluation of distal arteries by means of Doppler ultrasound provides more accurate information in terms of the identification of peripheral arterial disease.

  14. Abdominal abscesses with enteric communications: CT findings

    Energy Technology Data Exchange (ETDEWEB)

    Chintapalli, K.; Thorsen, M.K.; Foley, W.D.; Unger, G.F.

    1983-07-01

    CT examinations of four proven abdominal abscesses with enteric communications are reported. All the patients received oral contrast (3% Gastrografin solution). Three patients recieved rectal contrast. The patient who did not receive rectal contrast had a prior abdominoperineal resection. Contrast material was administered intravenously unless there was a contraindication or a suspected enteric vesical fistula. A representative case is described.

  15. Noncommunicating Isolated Enteric Duplication Cyst in the ...

    African Journals Online (AJOL)

    Noncommunicating isolated enteric duplications in the abdomen are an extremely rare variant of enteric duplications with their own blood supply. We report a case of a noncommunicating isolated ileal duplication in a 10-month-old boy. He was admitted because of severe abdominal distension and developed irritability ...

  16. Enteral Nutrition and Acute Pancreatitis: A Review

    NARCIS (Netherlands)

    Spanier, B.W.M.; Bruno, M.J.; Mathus-Vliegen, E.M.H.

    2011-01-01

    Introduction. In patients with acute pancreatitis (AP), nutritional support is required if normal food cannot be tolerated within several days. Enteral nutrition is preferred over parenteral nutrition. We reviewed the literature about enteral nutrition in AP. Methods. A MEDLINE search of the English

  17. Enteral nutrition and acute pancreatitis: A review

    NARCIS (Netherlands)

    B.W.M. Spanier (Marcel); M.J. Bruno (Marco); E.M.H. Mathus-Vliegen (Elisabeth)

    2011-01-01

    textabstractIntroduction. In patients with acute pancreatitis (AP), nutritional support is required if normal food cannot be tolerated within several days. Enteral nutrition is preferred over parenteral nutrition. We reviewed the literature about enteral nutrition in AP. Methods. A MEDLINE search of

  18. Understanding and controlling the enteric nervous system

    NARCIS (Netherlands)

    Boeckxstaens, G. E.

    2002-01-01

    The enteric nervous system or the `Little Brain' of the gut controls gastrointestinal motility and secretion, and is involved in visceral sensation. In this chapter, new developments in understanding the function of the enteric nervous system are described. In particular, the interaction of this

  19. Enteral nutrition in the critically ill.

    Science.gov (United States)

    Koruda, M J; Guenter, P; Rombeau, J L

    1987-01-01

    Although total parenteral nutrition has greatly influenced the clinical management of the critically ill, enteral nutrition can provide much needed support in the intensive care unit. In order to employ the best enteral nutrition, one must understand its rationale, delivery principles, equipment, feeding techniques, and diets, as well as patient selection and monitoring.

  20. Epi-aortic Doppler measurement of cardiac output in univentricular connection

    Directory of Open Access Journals (Sweden)

    Ad J J C Bogers

    2009-02-01

    Full Text Available Ad J J C Bogers1, Martin van den Burg1,2, Ronald Schepp2, Jan Klein21Department of Cardiothoracic Surgery; 2Department of Anesthesiology, Thoraxcentre, Erasmus University Medical Centre, Rotterdam, The NetherlandsBackground: In the initial postoperative period after a Fontan-type operation for a univentricular circulation, cardiac output information is important, but cannot be provided by conventional methods due to the surgical reconstruction of the heart. In this regard we investigated the feasibility of epi-aortic Doppler measurements in order to calculate cardiac output.Methods: Epi-aortic cardiac output measurement was compared with Fick measurements as the gold standard in eight patients with a univentricular circulation after a Fontan-type operation.Results: The mean diameter of the aorta by epi-aortic measurement was 18 mm (range 14 to 25, by angiography 17 mm (range 10 to 24, correlation coefficient 0.88 (p < 0.05. The mean cardiac output by epi-aortic measurement was 2.8 l.min−1 (range 1.2 to 6.3, by the Fick calculations 1.8 l.min−1 (range 0.8 to 5.0. The correlation coefficient for cardiac output data in aortic diameters up to 20 millimeter in diameter was 0.55 (p < 0.05.Conclusions: Epi-aortic Doppler measurement of cardiac output after Fontan type reconstructions could be applied in aortas up to 20 millimeter in diameter. A reasonable correlation with Fick calculations was found. This was supported by Bland–Altman plotting. The method is intrinsically invasive, but application and removal of the device were easy and no complications related to the system were observed. An important restriction is the often present abnormal anatomy, either congenitally or after surgery.Keywords: cardiac output, Fontan circulation, epi-aortic Doppler, extravascular Doppler

  1. Crohn's disease activity assessed by doppler sonography: the role of aortic flow parameters

    Directory of Open Access Journals (Sweden)

    Thais Guaraná Andrade

    2013-04-01

    Full Text Available OBJECTIVES: Intestinal neovascularization and abnormal abdominal arterial flow rates have been reported in Crohn's disease. The aim of this study was to evaluate Doppler sonography as a method for assessing Crohn's disease activity based on changes in splanchnic hemodynamics. METHODS: Forty-eight patients with Crohn's disease, 22 healthy volunteers and 12 patients with irritable bowel syndrome were evaluated by Doppler ultrasound for flow parameters of the aorta and superior mesenteric artery. This evaluation included the cross-sectional area, maximum flow volume, peak systolic velocity, end diastolic velocity, resistance and the pulsatility index. Disease activity was classified according to the Crohn's disease activity index. RESULTS: Most measurements in the aorta and superior mesenteric artery were significantly different between Crohn's disease patients and both control groups. Only the aortic maximum flow volume (CC = 0.37, p = 0.009 and aortic peak systolic velocity (CC = 0.30, p = 0.035 showed a significant positive correlation with the Crohn's disease activity index. The determination of cut-off points for the aortic maximum flow volume and peak systolic velocity measurements increased the sensitivity (80 and 75% for flow volume and velocity, respectively, specificity (57 and 75%, accuracy (67 and 75% and positive (57 and 68% and negative (80 and 81% predictive values. These cut-off values permitted the correct classification of most of the patients with Crohn's disease with respect to disease activity. None of the superior mesenteric artery measurements were able to discriminate patients in relation to disease activity. CONCLUSION: The aortic maximum flow volume and peak systolic velocity levels estimated by Doppler sonography reflected disease activity in Crohn's disease. Doppler sonography of the aorta is therefore a novel noninvasive adjunct method that may be useful in the clinical follow-up of patients with Crohn

  2. Tissue Doppler-derived indices predict exercise capacity in patients with apical hypertrophic cardiomyopathy.

    Science.gov (United States)

    Ha, Jong-Won; Cho, Jung-Rae; Kim, Jin-Mi; Ahn, Jeong-Ah; Choi, Eui-Young; Kang, Seok-Min; Rim, Se-Joong; Chung, Namsik

    2005-11-01

    Although impaired left ventricular (LV) diastolic function is a prominent feature of hypertrophic cardiomyopathy (HCM), diastolic function and its relation to exercise capacity in apical HCM (ApHCM) has not been explored previously. This study was sought to determine the relationship between diastolic mitral annular velocities combined with conventional Doppler indexes and exercise capacity in patients with ApHCM. Twenty-nine patients with ApHCM (24 men; mean age +/- SD, 57 +/- 10 years) underwent supine bicycle exercise with simultaneous respiratory gas analysis and two-dimensional and Doppler echocardiographic study. The mitral inflow velocities (early filling [E], late filling, and deceleration time) were traced and measured. Early diastolic mitral annular velocity (E') was measured at the septal corner of mitral annulus by Doppler tissue imaging (DTI) from the apical four-chamber view. Pro-brain natriuretic peptide (proBNP) was measured at the time of echocardiography using a quantitative electrochemiluminescence immunoassay. E/E' ratio correlated inversely with maximal oxygen uptake (Vo(2)max) [r = - 0.47, p = 0.0106]. There was a significant positive correlation between E' and Vo(2)max (r = 0.41, p = 0.024). However, no correlation was found between conventional two-dimensional, Doppler indices, and proBNP and Vo(2)max). Of all the echocardiographic and clinical parameters assessed, E/E' ratio had the best correlation with exercise capacity (r - 0.47) and was the strongest independent predictor of Vo(2)max by multivariate analysis (p = 0.0106). DTI-derived indexes (E', E/E' ratio), an estimate of myocardial relaxation and LV filling pressures, correlate with exercise capacity in patients with ApHCM, suggesting that abnormal diastolic function may be a factor limiting exercise capacity.

  3. Right Ventricular Doppler Echocardiographic Study of Indeterminate Form of Chagas Disease

    Directory of Open Access Journals (Sweden)

    Rogério Gomes Furtado

    2015-03-01

    Full Text Available Background: Patients with indeterminate form of Chagas disease/cardiac normality (ICD/CN exhibited normal electrocardiograms and chest X-rays; however, more sophisticated tests detected some degree of morphological and functional changes in the heart. Objective: To assess the prevalence of systolic and diastolic dysfunction of the right ventricle (RV in patients with ICD/CN. Methods: This was a case–control and prevalence study. Using Doppler two-dimensional echocardiography (2D, 92 patients were assessed and divided into two groups: group I (normal, n = 31 and group II (ICD/CN, n = 61. Results: The prevalence of RV systolic dysfunction in patients in groups I and II was as follows: fractional area change (0.0% versus 0.6%, mobility of the tricuspid annulus (0.0% versus 0.0%, and S-wave tissue Doppler (6.4% versus 26.0%, p = 0.016. The prevalence of global disorders such as the right myocardial performance index using tissue Doppler (16.1% versus 27.8%, p = 0.099 and pulsed Doppler (61.3% versus 68%, p = 0.141 and diastolic disorders such as abnormal relaxation (0.0% versus 6.0%, pseudonormal pattern (0.0% versus 0.0%, and restrictive pattern (0.0% versus 0.0% was not statistically different between groups. Conclusion: The prevalence of RV systolic dysfunction was estimated to be 26% (S wave velocity compared with other variables, suggesting incipient changes in RV systolic function in the ICD/CN group.

  4. Doppler velocimetry of ductus venous in preterm fetuses with brain sparing effect: neonatal outcome.

    Science.gov (United States)

    Cosmo, Ynesmara Coelho; Araujo Júnior, Edward; de Sá, Renato Augusto Moreira; de Carvalho, Paulo Roberto Nassar; Mattar, Rosiane; Lopes, Laudelino Marques; Nardozza, Luciano Marcondes Machado; de Souza, Eduardo; Moron, Antonio Fernandes

    2012-07-01

    to evaluate the relationship between ductus venous (DV) and Doppler velocimetry in neonatal outcome in severe compromised preterm fetuses. the study was designed as an observational and cross-sectional study with 52 premature neonates with brain sparing effect. The criteria of neonatal severe morbidity were: severe intraventricular hemorrhage (grades 3 or 4), retinopathy of prematurity (grade 3 or 4), cystic periventricular leukomalatia, bronchopneumo dysplasia and neonatal mortality. The fetuses were divided in two groups: group 0 - all the fetuses with ventricular systole/atrial contraction (S/A) in DV ratio values less them 3.4; group 1 - fetuses with values of S/A ratio greater than 3.4. 42% of fetuses showed abnormal S/A ratio in DV and 48% showed birth weight below percentile 3 for gestational age. There was no statistical significance comparing the 02 groups according to bronchopneumo dysplasia, retinopathy of prematurity (grade 3 or 4) and intraventricular hemorrhage (grade 3 or 4). Only one fetus presented cystic periventricular leukomalatia. We found statistically significant association between abnormal DV S/A ratio and neonatal mortality (CI 95%, 1.28 -38.22, pDoppler examination isn't associated with severe neonatal morbidity but with neonatal mortality.

  5. Water quality indicators: bacteria, coliphages, enteric viruses.

    Science.gov (United States)

    Lin, Johnson; Ganesh, Atheesha

    2013-12-01

    Water quality through the presence of pathogenic enteric microorganisms may affect human health. Coliform bacteria, Escherichia coli and coliphages are normally used as indicators of water quality. However, the presence of above-mentioned indicators do not always suggest the presence of human enteric viruses. It is important to study human enteric viruses in water. Human enteric viruses can tolerate fluctuating environmental conditions and survive in the environment for long periods of time becoming causal agents of diarrhoeal diseases. Therefore, the potential of human pathogenic viruses as significant indicators of water quality is emerging. Human Adenoviruses and other viruses have been proposed as suitable indices for the effective identification of such organisms of human origin contaminating water systems. This article reports on the recent developments in the management of water quality specifically focusing on human enteric viruses as indicators.

  6. 3D power Doppler ultrasound assessment of placental perfusion during uterine contraction in labor.

    Science.gov (United States)

    Sato, Miki; Noguchi, Junko; Mashima, Masato; Tanaka, Hirokazu; Hata, Toshiyuki

    2016-09-01

    To assess placental perfusion during spontaneous or induced uterine contraction in labor at term using placental vascular sonobiopsy (PVS) by 3D power Doppler ultrasound with the VOCAL imaging analysis program. PVS was performed in 50 normal pregnancies (32 in spontaneous labor group [SLG], and 18 in induced labor group with oxytocin or prostaglandin F2α [ILG]) at 37-41 weeks of gestation to assess placental perfusion during uterine contraction in labor. Only pregnancies with an entirely visualized anterior placenta were included in the study. Data acquisition was performed before, during (at the peak of contraction), and after uterine contraction. 3D power Doppler indices such as the vascularization index (VI), flow index (FI), and vascularization flow index (VFI) were calculated in each placenta. There were no abnormal fetal heart rate tracings during contraction in either group. VI and VFI values were significantly reduced during uterine contraction in both groups (SLG, -33.4% [-97.0-15.2%], and ILG, -49.6% [-78.2--4.0%]), respectively (P reduction in placental perfusion. Reduced placental blood flow in induced uterine contraction has a tendency to be marked compared with that in spontaneous uterine contraction. To the best of our knowledge, this is the first study on the non-invasive assessment of placental perfusion during uterine contraction in labor using 3D power Doppler ultrasound. However, the data and their interpretation in the present study should be taken with some degree of caution because of the small number of subjects studied. Further studies involving a larger sample size are needed to assess placental perfusion and vascularity using PVS during normal and abnormal uterine contractions in normal and high-risk pregnancies. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Doppler ultrasound and magnetic resonance for evaluation of patients treated surgically for aortic coarctation. Ecografia Doppler y resonancia magnetica en la evaluacion de pacientes con coartacion de aorta operada

    Energy Technology Data Exchange (ETDEWEB)

    Canteli, B.; Saez, F.; Garcia, F.; Cabrera, A.; Galdeano, J.M.; Rodriguez, O. (Hospital de Cruzes, Vizcaya (Spain))

    1994-01-01

    Doppler ultrasound and magnetic resonance were performed in a series of 39 patients who had been treated surgically for aortic coarctation. The purpose was to assess the different Doppler gradients, comparing the findings with morphological data disclosed by magnetic resonance. The aortic caliber in the operative field was pathological in 7 patients (ratio between the caliber at the level of the lesion and that of descending aorta of less than 0.7). When the patients were considered as a group. Doppler ultrasound did not show satisfactory sensitivity (29%-43%), specificity (74%) or positive predictive value (17%-23%). Only the negative predictive value (85%-88%) presented more favorable results. When the Subgroup of patients without associated cardiac abnormalities or collateral circulation was studied alone, the following results were found: sensitivity, 100%; specificity, 81%-90%, positive predictive value, 33%-50%, negative predictive value, 100%, similar to those reported in the literature. Thus, we consider that Doppler ultrasound is a harmless and low cost diagnostic method that is highly suitable for follow-up of these patients, within certain limits. Magnetic resonance is the method of choice for the noninvasive assessment of aortic morphology. (Author)

  8. Enteral and parenteral nutrition in patients with enteric fistulas and short bowel syndrome.

    Science.gov (United States)

    Rombeau, J L; Rolandelli, R H

    1987-06-01

    Significant advances in the use of enteral and parenteral nutrition in patients with either enteric fistulas or short bowel syndrome include increased usage of enteral nutrition because of its trophic effects on the gut and increased usage of both enteral and parenteral nutrition in the home setting. Current investigations are directed toward identifying gut-specific fuels and dietary and pharmacologic enhancement of nutrient utilization.

  9. Doppler angle correction in the measurement of intrarenal parameters

    Directory of Open Access Journals (Sweden)

    Mennitt K

    2011-03-01

    Full Text Available Jing Gao¹, Keith Hentel¹, Qiang Zhu², Teng Ma², George Shih¹, Kevin Mennitt¹, Robert Min¹¹Department of Radiology, New York Presbyterian Hospital, Weill Cornell Medical College, NY, USA; ²Division of Diagnostic Ultrasound, Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, ChinaBackground: The aim of this study was to assess differences in intrarenal artery Doppler parameters measured without and with Doppler angle correction.Methods: We retrospectively reviewed color duplex sonography in 30 normally functioning kidneys (20 native kidneys in 10 subjects and 10 transplanted kidneys in 10 subjects performed between January 26, 2010 and July 26, 2010. There were 10 age-matched men and10 age-matched women (mean 39.8 ± 12.2, range 21–60 years in this study. Depending on whether the Doppler angle was corrected in the spectral Doppler measurement, Doppler parameters including peak systolic velocity (PSV, end-diastolic velocity (EDV, and resistive index (RI measured at the interlobar artery of the kidney were divided into two groups, ie, initial Doppler parameters measured without Doppler angle correction (Group 1 and remeasured Doppler parameters with Doppler angle correction (Group 2. Values for PSV, EDV, and RI measured without Doppler angle correction were compared with those measured with Doppler angle correction, and were analyzed statistically with a paired-samples t-test.Results: There were statistical differences in PSV and EDV at the interlobar artery in the upper, mid, and lower poles of the kidney between Group 1 and Group 2 (all P < 0.001. PSV and EDV in Group 1 were significantly lower than in Group 2. RI in Group 1 was the same as that in Group 2 in the upper, mid, and lower poles of the kidneys.Conclusion: Doppler angle correction plays an important role in the accurate measurement of intrarenal blood flow velocity. The true flow velocity converted from the maximum Doppler velocity shift

  10. Doppler changes as the earliest parameter in fetal surveillance to detect fetal compromise in intrauterine growth-restricted fetuses

    Directory of Open Access Journals (Sweden)

    Bansal Saloni

    2016-01-01

    Full Text Available Introduction. It is estimated that 3-10% of infants are growth restricted. Growth disturbances may have long-term issues. Doppler allows insight into the fetal response to intrauterine stress. Objective. The aim of this study was to detect fetal compromise in intrauterine growth-restricted (IUGR fetuses by means of biophysical profile (BPP vis-а-vis Doppler velocimetry studies of the fetal umbilical artery, and to find out which of the two is a better and earlier predictor of fetal compromise. Methods. A prospective study was conducted on a total of 50 singleton pregnancies with IUGR between 28 and 42 weeks of gestation. Study patients were managed expectantly with nonstress testing and amniotic fluid assessment, BPP and Doppler velocimetry studies of the fetal umbilical artery. Results. Fetal outcome was poor in 5/50 (10% of the fetuses, defined as presence of all of the following: poor Apgar test score, neonatal intensive care unit stay, necrotizing enterocolitis, and low birth weight. Of the four with abnormal BPP, 50% had poor fetal outcomes. Out of 46 with normal BPP, 6.5% had poor fetal outcomes. Conclusion. Inference drawn from the study is that the Doppler technology provides us the opportunity for repetitive noninvasive hemodynamic monitoring in IUGR pregnancies.

  11. Experimentally induced acute uric acid nephropathy in rabbits: Findings of high resolution gray scale and doppler ultrasonographies

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Ik; Chung, Soo Young; Lee, Kyung Won; Kim, Hong Dae; Ko, Eun Young; Won, Mi Sook; Noh, Jung Woo [Hallym University College of Medicine, Seoul (Korea, Republic of); Park, Moon Hyang [Hanyang University College of Medicine, Seoul (Korea, Republic of)

    2001-12-15

    To evaluate changes of the high-resolution (HR) gray scale and doppler ultrasonographic (US) characteristics of experimentally induced acute uric acid (UA) nephropathy in rabbits. Acute UA nephropathy was induced in ten rabbits using supersaturated lithium carbonate solution. The rabbits were divided in two groups. Group I consisted of five rabbits, and they were injected with a single dose of 150 ml of saturated UA over one hour. During tis period, serial US studies of the kidneys of these rabbits were performed every ten minutes. Group II consisted of the remaining five rabbits, and three injections of 50 ml of saturated UA solution were given on the first, fifth and eight day and follow-up was done upto twenty fifth day. Sequential HR and Doppler US, renal biopsy and blood sampling were performed on day 1, 5, 8, 21, and 25 in the group II rabbits. In group I, HR and Doppler US examination revealed the normal resistive index without significant abnormality. On the other hand, US studies of group II showed poor renal corticomedullary differentiation, decreased renal blood flow and elevated resistive index. There was statistically significant correlation among US findings, histologic characteristics and chemical index (BUN, creatinine) of renal function. In addition, sequentially increased size and volume of the kidney were noted in both groups. HR gray scale and doppler US characteristics of experimentally induced acute UA nephropathy in rabbits were similar to those of acute renal failure caused by other well-known causes.

  12. PENILE DOPPLER IN THE EVALUATION OF ERECTILE DYSFUNCTION

    OpenAIRE

    Ajmal Shad; Ravichandra; Devdas; Vasu; De, Vivek

    2014-01-01

    Color doppler sonography can be useful in the evaluation of erectile dysfunction, which can result from psychogenic, endocrinologic, neurogenic, pharmacologic, and vasogenic causes. OBJECTIVE: To assess the role of Color doppler sonography in the evaluation of erectile dysfunction. MATERIAL AND METHODS: A cross-sectional study of twelve men with erectile dysfunction (between the age group of 45-60 years) underwent penile color doppler sonography. The hemodynamic function o...

  13. Influence of Doppler Bin Width on GNSS Detection Probabilities

    CERN Document Server

    Geiger, Bernhard C

    2011-01-01

    The acquisition stage in GNSS receivers determines Doppler shifts and code phases of visible satellites. Acquisition is thus a search in two continuous dimensions, where the digital algorithms require a partitioning of the search space into cells. We present analytic expressions for the acquisition performance depending on the partitioning of the Doppler frequency domain. In particular, the impact of the number and width of Doppler bins is analyzed. The presented results are verified by simulations.

  14. Path-length-resolved optical Doppler perfusion monitoring

    OpenAIRE

    Varghese, Babu; Rajan, Vinayakrishnan; van Leeuwen, Ton; Steenbergen, Wiendelt

    2007-01-01

    We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion ...

  15. Applications of Doppler ultrasound in clinical vascular disease

    Science.gov (United States)

    Barnes, R. W.; Hokanson, D. E.; Sumner, D. S.; Strandness, D. E., Jr.

    1975-01-01

    Doppler ultrasound has become the most useful and versatile noninvasive technique for objective evaluation of clinical vascular disease. Commercially available continuous-wave instruments provide qualitative and quantitative assessment of venous and arterial disease. Pulsed Doppler ultrasound was developed to provide longitudinal and transverse cross-sectional images of the arterial lumen with a resolution approaching that of conventional X-ray techniques. Application of Doppler ultrasound in venous, peripheral arterial, and cerebrovascular diseases is reviewed.

  16. Enteral fluid therapy in large animals.

    Science.gov (United States)

    Rainger, J E; Dart, A J

    2006-12-01

    Enteral fluids administered alone, or in conjunction with intravenous fluids, are reported to be useful for the treatment of dehydration and electrolyte loss associated with diarrhoea in a number of species, following exercise in horses and for feed impaction of the large intestine of horses. Enteral fluids are suitable for treatment of mild to moderately dehydrated patients with some intact intestinal epithelium and motile small intestine. In patients that will drink voluntarily or tolerate nasal intubation the use of enteral fluids may avoid the complications associated with intravenous fluid administration. However the labour costs associated with repeated nasal intubation in intensively managed patients requiring large volumes of fluids may make the use of enteral fluids less economical than intravenous fluid administration. Enteral fluid use alone is contraindicated in patients that are severely dehydrated and/or in hypovolaemic shock, however, if used in conjunction with intravenous fluids, the effects of villous atrophy and malnutrition may be ameliorated and the duration of hospitalisation shortened. There is a variety of commercially available enteral fluids available to veterinary practitioners. While the key components of these fluids are sodium, chloride and carbohydrates, the amounts of ions and other ingredients such as potassium, alkalising agents, amino acids and shortchain fatty acids may vary. The species of the animal, the underlying condition, and the constituents of the fluid, should influence the choice of an enteral fluid.

  17. EUV Doppler Imaging for CubeSat Platforms Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Mature the design and fabricate the Flare Initiation Doppler Imager (FIDI) instrument to demonstrate low-spacecraft-resource EUV technology (most notably,...

  18. Path-length-resolved optical Doppler perfusion monitoring.

    Science.gov (United States)

    Varghese, Babu; Rajan, Vinayakrishnan; Van Leeuwen, Ton G; Steenbergen, Wiendelt

    2007-01-01

    We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion are measured in real time for a given optical path length, and the results are compared with the perfusion signal obtained with a conventional laser Doppler perfusion monitor.

  19. Analysis of multiple scattering effects in optical Doppler tomography

    DEFF Research Database (Denmark)

    Yura, H.T.; Thrane, L.; Andersen, Peter E.

    2005-01-01

    Optical Doppler tomography (ODT) combines Doppler velocimetry and optical coherence tomography (OCT) to obtain high-resolution cross-sectional imaging of particle flow velocity in scattering media such as the human retina and skin. Here, we present the results of a theoretical analysis of ODT where...... Doppler frequency spectrum. Thus, in the present analysis, the dependence of the mean and standard deviation of the Doppler shift on the scattering properties of the flowing medium are obtained. Taking the multiple scattering effects into account, we are able to explain previous measurements of depth...

  20. Eliminating Doppler Effects in Synthetic-Aperture Radar Optical Processors

    Science.gov (United States)

    Constantindes, N. J.; Bicknell, T. J.

    1984-01-01

    Pair of photodetectors generates correction signals. Instrument detects Doppler shifts in radar and corrects processing parameters so ambiguities caused by shifts not manifested as double or overlapping images.

  1. Reexamination of the Doppler effect through Maxwell's equations.

    Science.gov (United States)

    Guo, Wei; Aktas, Yildirim

    2012-08-01

    In this work, the electric field emitted from a moving source, an electric point dipole, is analyzed for the purpose of illustrating the physics behind the Doppler effect. It is found that if the (translational) motion of the source is nonrelativistic, the Doppler effect is realized in two steps: the motion of the source first causes the dyadic Green function associated with the electric field to acquire an oscillation frequency in the far-field region of the source, and then the frequency leads to the Doppler effect. It is also demonstrated that the Doppler effect is observable only in the far-field region of the source.

  2. Evaluating Peripheral Vascular Injuries: Is Color Doppler Enough for Diagnosis?

    Directory of Open Access Journals (Sweden)

    Mohd Lateef Wani

    2014-03-01

    Full Text Available Background:: Vascular injury poses a serious threat to limb and life. Thus, diagnosis should be made immediately with minimally invasive methods. Doppler is a good aid in diagnosis of vascular injury. Methods:: The present prospective study was conducted on 150 patients who presented with soft signs (the signs which are suggestive but not confirmatory of vascular injury. They were subjected to color Doppler examination before exploration. The patients with the features of vascular injury on color Doppler were subjected to exploration. On the other hand, those who had normal Doppler were subjected to CT- angiography. Then, the findings of the exploration were matched with those of color Doppler. The data were analyzed using the SPSS statistical software. Results:: Out of the 150 Doppler examinations, 110 (73.33% were reported as positive, while 40 were reported as negative for vascular injury. These were subjected to CT-angiography and seven of them had the features of vascular injury on CT-angiography. All the patients with positive Doppler or CT angiography findings were subjected to exploration. Doppler had a sensitivity of 94% and specificity of 82.5% in diagnosis of vascular injury using Binary classification test. Conclusions:: Color Doppler is an easily available, reliable, and handy method of diagnosing a vascular injury. It has a very high sensitivity and specificity in diagnosis of vascular injuries.

  3. Burst Format Design for Optimum Joint Estimation of Doppler-Shift and Doppler-Rate in Packet Satellite Communications

    Directory of Open Access Journals (Sweden)

    Luca Giugno

    2007-05-01

    Full Text Available This paper considers the problem of optimizing the burst format of packet transmission to perform enhanced-accuracy estimation of Doppler-shift and Doppler-rate of the carrier of the received signal, due to relative motion between the transmitter and the receiver. Two novel burst formats that minimize the Doppler-shift and the Doppler-rate Cramér-Rao bounds (CRBs for the joint estimation of carrier phase/Doppler-shift and of the Doppler-rate are derived, and a data-aided (DA estimation algorithm suitable for each optimal burst format is presented. Performance of the newly derived estimators is evaluated by analysis and by simulation, showing that such algorithms attain their relevant CRBs with very low complexity, so that they can be directly embedded into new-generation digital modems for satellite communications at low SNR.

  4. Transmission media effects on precise Doppler tracking

    Science.gov (United States)

    Callahan, P. S.

    1978-01-01

    The effects of the transmission media - the earth's troposphere and ionosphere, and the solar wind - on precise Doppler tracking are discussed. The charged particle effects can be largely removed by dual frequency observations; however there are limitations to these corrections (besides system noise and/or finite integration times) including the effects of magnetic fields, diffraction, and differential refraction, all of which must be carefully evaluated. The earth's troposphere can contribute an error of delta f/f approximately 10 to the minus 14th power.

  5. [Color Doppler sonography of focal abdominal lesions].

    Science.gov (United States)

    Licanin, Zoran; Lincender, Lidija; Djurović, V; Salihefendić, Nizama; Smajlović, Fahrudin

    2004-01-01

    Color Doppler sonography (CDS--spectral, color and power), harmonic imaging techniques (THI, PHI), possibility of 3D analysis of picture, usage of contrast agents, have raised the values of ultrasound as a diagnostic method to a very high level. THI--non-linear gray scale modality, is based on the processing of higher reflected frequencies, that has improved a picture resolution, which is presented with less artifacts and limiting effects of obesity and gases. Ultrasound contrast agents improve analysis of micro and macro circulation of the examined area, and with the assessment of velocity of supply in ROI (wash in), distribution and time of signal weakening (wash out), are significantly increasing diagnostic value of ultrasound. Besides the anatomical and topographic presentation of examined region (color, power), Color Doppler sonography gives us haemodynamic-functional information on vascularisation of that region, as well as on pathologic vascularisation if present. Avascular aspect of a focal pathologic lesion corresponds to a cyst or haematoma, while coloration and positive spectral curve discover that anechogenic lesions actually represents aneurysms, pseudoaneurysms or AVF. In local inflammatory lesion, abscess in an acute phase, CDS shows first increased, and then decreased central perfusion, while in a chronic phase, a pericapsular vascularisation is present. Contribution of CDS in differentiation of hepatic tumors (hemangioma, HCC and metastasis) is very significant. Central color dots along the peripheral blood vessels and the blush phenomenon are characteristics of capillary hemangioma, peritumoral vascular ring "basket" of HCC, and "detour" sign of metastasis. The central artery, RI from 0.45 to 0.60 and radial spreading characterize FNH. Hepatic adenoma is characterized by an intratumoral vein, and rarely by a vascular hallo. Further on, blood velocity in tumor defined by Color Doppler, distinguishes malignant from benign lesion, where 40 cm/s is a

  6. Lupus enteritis: from clinical findings to therapeutic management

    Science.gov (United States)

    2013-01-01

    Lupus enteritis is a rare and poorly understood cause of abdominal pain in patients with systemic lupus erythematosus (SLE). In this study, we report a series of 7 new patients with this rare condition who were referred to French tertiary care centers and perform a systematic literature review of SLE cases fulfilling the revised ACR criteria, with evidence for small bowel involvement, excluding those with infectious enteritis. We describe the characteristics of 143 previously published and 7 new cases. Clinical symptoms mostly included abdominal pain (97%), vomiting (42%), diarrhea (32%) and fever (20%). Laboratory features mostly reflected lupus activity: low complement levels (88%), anemia (52%), leukocytopenia or lymphocytopenia (40%) and thrombocytopenia (21%). Median CRP level was 2.0 mg/dL (range 0–8.2 mg/dL). Proteinuria was present in 47% of cases. Imaging studies revealed bowel wall edema (95%), ascites (78%), the characteristic target sign (71%), mesenteric abnormalities (71%) and bowel dilatation (24%). Only 9 patients (6%) had histologically confirmed vasculitis. All patients received corticosteroids as a first-line therapy, with additional immunosuppressants administered either from the initial episode or only in case of relapse (recurrence rate: 25%). Seven percent developed intestinal necrosis or perforation, yielding a mortality rate of 2.7%. Altogether, lupus enteritis is a poorly known cause of abdominal pain in SLE patients, with distinct clinical and therapeutic features. The disease may evolve to intestinal necrosis and perforation if untreated. Adding with this an excellent steroid responsiveness, timely diagnosis becomes primordial for the adequate management of this rare entity. PMID:23642042

  7. Radiological findings of uterine arteriovenous malformation: a case report of an unusual and life-threatening cause of abnormal vaginal bleeding

    Directory of Open Access Journals (Sweden)

    Marcela Sales Farias

    2014-04-01

    Full Text Available Uterine arteriovenous malformations may cause life-threatening abnormal genital bleeding in women at childbearing age. Transvaginal Doppler ultrasonography is a widely available, noninvasive and excellent diagnostic method. The authors report the case of a patient with history of gestational trophoblastic disease and multiple curettage procedures who developed uterine arteriovenous malformations, with remission of the lesions after treatment with methotrexate.

  8. Pneumatosis intestinalis associated with enteral tube feeding

    National Research Council Canada - National Science Library

    Zorgdrager, Marcel; Pol, Robert

    2013-01-01

    ...). Explorative laparotomy showed an omental band adhesion without signs of ischaemia. After a short period of total parenteral nutrition PI resolved almost completely and enteral tube feeding could be continued once again...

  9. Endoscopic placement of enteral feeding tubes.

    Science.gov (United States)

    Rafferty, Gerard P; Tham, Tony Ck

    2010-05-16

    Malnutrition is common in patients with acute and chronic illness. Nutritional management of these malnourished patients is an essential part of healthcare. Enteral feeding is one component of nutritional support. It is the preferred method of nutritional support in patients that are not receiving adequate oral nutrition and have a functioning gastrointestinal tract (GIT). This method of nutritional support has undergone progression over recent times. The method of placement of enteral feeding tubes has evolved due to development of new feeding tubes and endoscopic technology. Enteral feeding can be divided into methods that provide short-term and long-term access to the GIT. This review article focuses on the current range of methods of gaining access to the GIT to provide enteral feed.

  10. American Society for Parenteral & Enteral Nutrition

    Science.gov (United States)

    ... Center Advertising and Sponsorship Learn More ASPEN Enteral Nutrition by the Numbers: EN Data Across the Healthcare Continuum Learn More The ASPEN Adult Nutrition Support Core Curriculum, 3rd Edition Has Arrived! The ...

  11. Duck Virus Enteritis - A Contingency Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Duck plague, also known as duck virus enteritis (DVE) is a highly contagious, extremely deadly epizootic virus with a potential for devastating continental waterfowl...

  12. Abnormal Liver Function Tests in an Anorexia Nervosa Patient and an Atypical Manifestation of Refeeding Syndrome

    Directory of Open Access Journals (Sweden)

    Vamshidhar R. Vootla

    2015-07-01

    Full Text Available Refeeding syndrome is defined as electrolyte and fluid abnormalities that occur in significantly malnourished patients when they are refed orally, enterally, or parenterally. The principal manifestations include hypophosphatemia, hypokalemia, vitamin deficiencies, volume overload and edema. This can affect multiple organ systems, such as the cardiovascular, pulmonary, or neurological systems, secondary to the above-mentioned abnormalities. Rarely, patients may develop gastrointestinal symptoms and show abnormal liver function test results. We report the case of a 52-year-old woman with anorexia nervosa who developed refeeding syndrome and simultaneous elevations of liver function test results, which normalized upon the resolution of the refeeding syndrome.

  13. Doppler ultrasound scan during normal gestation: umbilical circulation; Ecografia Doppler en la gestacion normal: circulacion umbilical

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz, T.; Sabate, J.; Martinez-Benavides, M. M.; Sanchez-Ramos, J. [Hospital Virgen Macarena. Sevilla (Spain)

    2002-07-01

    To determine normal umbilical circulation patterns by means of Doppler ultrasound scan in a healthy gestating population without risk factors and with normal perinatal results, and to evaluate any occurring modifications relative to gestational age by obtaining records kept during pregnancy. One hundred and sixteen pregnant women carrying a single fetus have been studied. These women had no risk factors, with both clinical and analytical controls, as well as ultrasound scans, all being normal. There were performed a total of 193 Doppler ultrasound scans between weeks 15 and 41 of gestation, with blood-flow analysis in the arteries and vein of the umbilical cord. The obtained information was correlated with parameters that evaluate fetal well-being (fetal monitoring and/or oxytocin test) and perinatal result (delivery type, birth weight, Apgar score). Statistical analysis was performed with the programs SPSS 6.0.1 for Windows and EPIINFO 6.0.4. With pulsed Doppler, the umbilical artery in all cases demonstrated a biphasic morphology with systolic and diastolic components and without retrograde blood flow. As the gestation period increased, there was observed a progressive decrease in resistance along with an increase in blood-flow velocity during the diastolic phase. The Doppler ultrasound scan is a non-invasive method that permits the hemodynamic study of umbilical blood circulation. A knowledge of normal blood-flow signal morphology, as well as of the normal values for Doppler indices in relation to gestational age would permit us to utilize this method in high-risk pregnancies. (Author) 30 refs.

  14. [Indications and practice of enteral nutrition].

    Science.gov (United States)

    Hallay, Judit; Nagy, Dániel; Fülesdi, Béla

    2014-12-21

    Malnutrition in hospitalised patients has a significant and disadvantageous impact on treatment outcome. If possible, enteral nutrition with an energy/protein-balanced nutrient should be preferred depending on the patient's condition, type of illness and risk factors. The aim of the nutrition therapy is to increase the efficacy of treatment and shorten the length of hospital stay in order to ensure rapid rehabilitation. In the present review the authors summarize the most important clinical and practical aspects of enteral nutrition therapy.

  15. Medication administration through enteral feeding tubes.

    Science.gov (United States)

    Williams, Nancy Toedter

    2008-12-15

    An overview of enteral feeding tubes, drug administration techniques, considerations for dosage form selection, common drug interactions with enteral formulas, and methods to minimize tube occlusion is given. Enteral nutrition through a feeding tube is the preferred method of nutrition support in patients who have a functioning gastrointestinal tract but who are unable to be fed orally. This method of delivering nutrition is also commonly used for administering medications when patients cannot swallow safely. However, several issues must be considered with concurrent administration of oral medications and enteral formulas. Incorrect administration methods may result in clogged feeding tubes, decreased drug efficacy, increased adverse effects, or drug-formula incompatibilities. Various enteral feeding tubes are available and are typically classified by site of insertion and location of the distal tip of the feeding tube. Liquid medications, particularly elixirs and suspensions, are preferred for enteral administration; however, these formulations may be hypertonic or contain large amounts of sorbitol, and these properties increase the potential for adverse effects. Before solid dosage forms are administered through the feeding tube, it should be determined if the medications are suitable for manipulation, such as crushing a tablet or opening a capsule. Medications should not be added directly to the enteral formula, and feeding tubes should be properly flushed with water before and after each medication is administered. To minimize drug-nutrient interactions, special considerations should be taken when administering phenytoin, carbamazepine, warfarin, fluoroquinolones, and proton pump inhibitors via feeding tubes. Precautions should be implemented to prevent tube occlusions, and immediate intervention is required when blockages occur. Successful drug delivery through enteral feeding tubes requires consideration of the tube size and placement as well as careful

  16. Endoscopic placement of enteral feeding tubes

    OpenAIRE

    Rafferty, Gerard P; Tham, Tony CK

    2010-01-01

    Malnutrition is common in patients with acute and chronic illness. Nutritional management of these malnourished patients is an essential part of healthcare. Enteral feeding is one component of nutritional support. It is the preferred method of nutritional support in patients that are not receiving adequate oral nutrition and have a functioning gastrointestinal tract (GIT). This method of nutritional support has undergone progression over recent times. The method of placement of enteral feedin...

  17. Correlates of protection for enteric vaccines.

    Science.gov (United States)

    Holmgren, Jan; Parashar, Umesh D; Plotkin, Stanley; Louis, Jacques; Ng, Su-Peing; Desauziers, Eric; Picot, Valentina; Saadatian-Elahi, Mitra

    2017-06-08

    An immunological Correlate of Protection (CoP) is an immune response that is statistically interrelated with protection. Identification of CoPs for enteric vaccines would help design studies to improve vaccine performance of licensed vaccines in low income settings, and would facilitate the testing of future vaccines in development that might be more affordable. CoPs are lacking today for most existing and investigational enteric vaccines. In order to share the latest information on CoPs for enteric vaccines and to discuss novel approaches to correlate mucosal immune responses in humans with protection, the Foundation Mérieux organized an international conference of experts where potential CoPs for vaccines were examined using case-studies for both bacterial and viral enteric pathogens. Experts on the panel concluded that to date, all established enteric vaccine CoPs, such as those for hepatitis A, Vi typhoid and poliovirus vaccines, are based on serological immune responses even though these may poorly reflect the relevant gut immune responses or predict protective efficacy. Known CoPs for cholera, norovirus and rotavirus could be considered as acceptable for comparisons of similarly composed vaccines while more work is still needed to establish CoPs for the remaining enteric pathogens and their candidate vaccines. Novel approaches to correlate human mucosal immune responses with protection include the investigation of gut-originating antibody-secreting cells (ASCs), B memory cells and follicular helper T cells from samples of peripheral blood during their recirculation. Copyright © 2017.

  18. S-Band Doppler Wave Radar System

    Directory of Open Access Journals (Sweden)

    Zezong Chen

    2017-12-01

    Full Text Available In this paper, a novel shore-based S-band microwave Doppler coherent wave radar (Microwave Ocean Remote SEnsor (MORSE is designed to improve wave measurements. Marine radars, which operate in the X band, have been widely used for ocean monitoring because of their low cost, small size and flexibility. However, because of the non-coherent measurements and strong absorption of X-band radio waves by rain, these radar systems suffer considerable performance loss in moist weather. Furthermore, frequent calibrations to modify the modulation transfer function are required. To overcome these shortcomings, MORSE, which operates in the S band, was developed by Wuhan University. Because of the coherent measurements of this sensor, it is able to measure the radial velocity of water particles via the Doppler effect. Then the relation between the velocity spectrum and wave height spectrum can be used to obtain the wave height spectra. Finally, wave parameters are estimated from the wave height spectra by the spectrum moment method. Comparisons between MORSE and Waverider MKIII are conducted in this study, and the results, including the non-directional wave height spectra, significant wave height and average wave period, are calculated and displayed. The correlation coefficient of the significant wave height is larger than 0.9, whereas that of the average wave period is approximately 0.4, demonstrating the effectiveness of MORSE for the continuous monitoring of ocean areas with high accuracy.

  19. Fusion of Telescopic and Doppler Radar Data

    Science.gov (United States)

    Navara, M.; Matousek, M.; Drbohlav, O.

    2014-09-01

    We study the possibilities of observations of satellites at circular LEO orbits simultaneously by a telescope and a bistatic continuous-wave Doppler radar. Telescopic images allow for trajectory determination except for its distance (and hence height). Assuming a circular orbit, the height can be computed from the angular speed, but this is often impossible for LEO objects which do not remain in the field of view during the whole exposure time. To restore the missing information, we use Doppler radar data from a radio astronomy network, originally designed for detection of meteors. Using simulated perturbations of real radar data we studied their influence on the estimates of (i) permanent parameters of trajectory (orbital elements), (ii) instantaneous parameters of trajectory, (iii) distance and height estimates if the other parameters are given by the telescopic data. We derived recommendations for the optimal positions of the transmitter and receivers leading to the best resolution. We also discuss possible ways of improvement of this technique. Fusion results are shown on a suite of several matched radar and telescopic satellite fly-over data.

  20. Colour Doppler flow imaging findings in portal biliopathy.

    Science.gov (United States)

    Gulati, Gurpreet; Pawa, Sumedha; Chowdhary, Veena; Kumar, Nirmal; Mittal, Santosh Kumar

    2003-01-01

    Biliary abnormalities in extrahepatic portal vein obstruction (EHPVO) have been described in detail on endoscopic retrograde cholangiopancreaticography (ERCP), but have never before been reported on colour Doppler flow imaging (CDFI). These changes occur either due to extrinsic compression of the bile ducts or due to ischaemic biliary stenosis. The aim of this study was to evaluate the role of CDFI in demonstrating the biliary changes in patients with EHPVO. Three out of 46 patients with EHPVO (7%), who presented clinically with obstructive jaundice, were subjected to a detailed CDFI study of the abdomen, followed by ERCP and splenoportovenography (SPV). One of the patients also underwent a repeat CDFI examination at 8 weeks following a lienorenal shunt. In all 3 cases, CDFI easily distinguished the anechoeic structures seen on ultrasound at the porta hepatis as periportal collaterals, the hepatic artery and dilated bile ducts. It revealed the actual indentation made on the common bile duct (CBD) by the collaterals besides showing the presence of biliary calculi. Gallbladder varices were also well demonstrated in all the cases. ERCP confirmed the presence of portal biliopathy besides showing other changes, such as angulation, displacement and stricture of the CBD. SPV confirmed the presence of EHPVO. One patient who underwent shunt surgery showed persistent dilatation of the CBD with calculi. CDFI is a rapid, non-invasive and widely available modality which can be used to demonstrate the biliary changes in patients with EHPVO with obstructive jaundice. It may thus help screen patients who require a further by ERCP examination for the planning of treatment.

  1. Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction.

    Directory of Open Access Journals (Sweden)

    Andreu Viader

    Full Text Available Mitochondrial dysfunction is a central mediator of disease progression in diverse neurodegenerative diseases that often present with prominent gastrointestinal abnormalities. Gastrointestinal dysfunction in these disorders is related, at least in part, to defects in the enteric nervous system (ENS. The role of mitochondrial deficits in ENS neurodegeneration and their relative contribution to gastrointestinal dysfunction, however, are unclear. To better understand how mitochondrial abnormalities in the ENS influence enteric neurodegeneration and affect intestinal function, we generated mice (Tfam-ENSKOs with impaired mitochondrial metabolism in enteric neurons and glia through the targeted deletion of the mitochondrial transcription factor A gene (Tfam. Tfam-ENSKO mice were initially viable but, at an early age, they developed severe gastrointestinal motility problems characterized by intestinal pseudo-obstruction resulting in premature death. This gastrointestinal dysfunction was caused by extensive, progressive neurodegeneration of the ENS involving both neurons and glia. Interestingly, mitochondrial defects differentially affected specific subpopulations of enteric neurons and regions of the gastrointestinal tract. Mitochondrial deficiency-related neuronal and glial loss was most prominent in the proximal small intestine, but the first affected neurons, nitrergic inhibitory neurons, had the greatest losses in the distal small intestine. This regional and subtype-specific variability in susceptibility to mitochondrial defects resulted in an imbalance of inhibitory and excitatory neurons that likely accounts for the observed phenotype in Tfam-ENSKO mice. Mitochondrial dysfunction, therefore, is likely to be an important driving force of neurodegeneration in the ENS and contribute to gastrointestinal symptoms in people with neurodegenerative disorders.

  2. 21 CFR 892.1550 - Ultrasonic pulsed doppler imaging system.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1550 Ultrasonic pulsed doppler imaging... features of continuous wave doppler-effect technology with pulsed-echo effect technology and is intended to... include signal analysis and display equipment, patient and equipment supports, component parts, and...

  3. The value of Doppler ultrasound in cirrhosis and portal hypertension

    NARCIS (Netherlands)

    Kok, T; van der Jagt, EJ; Haagsma, EB; Bijleveld, CMA; Jansen, PLM; Boeve, WJ

    1999-01-01

    Background: Cirrhosis and portal hypertension affect the flow profile of the liver vasculature. In these conditions Doppler ultrasound can provide important information on the hemodynamics of the portal venous system, the hepatic artery and the hepatic veins. Methods: The value of Doppler ultrasound

  4. Imaging doppler velocimeter with downward heterodyning in the optical domain

    Science.gov (United States)

    Reu, Phillip L; Hansche, Bruce D

    2013-05-21

    In a Doppler velocimeter, the incoming Doppler-shifted beams are heterodyned to reduce their frequencies into the bandwidth of a digital camera. This permits the digital camera to produce at every sampling interval a complete two-dimensional array of pixel values. This sequence of pixel value arrays provides a velocity image of the target.

  5. Uterine artery Doppler study in second trimester of pregnancy ...

    African Journals Online (AJOL)

    Introduction: The uterine artery Doppler has potentials for screening for complications of impaired placentation. This study examines the indices of uterine artery impedance at 22-23 weeks gestation and their relationship with maternal age and parity. Methods: Uterine artery colour imaging and pulsed wave Doppler ...

  6. Distribution of Doppler Redshifts of Associated Absorbers of SDSS ...

    Indian Academy of Sciences (India)

    Doppler redshifts of a sample of Mg II associated absorbers of SDSS DR7 quasars are analysed. We find that there might be three Gaussian components in the distribution of the Doppler redshift. The first Gaussian component, with the peak being located at Dopp = -0.0074, probably arises from absorbers with outflow ...

  7. Compressive sensing for high resolution profiles with enhanced Doppler performance

    NARCIS (Netherlands)

    Anitori, L.; Hoogeboom, P.; Chevalier, F. Le; Otten, M.P.G.

    2012-01-01

    In this paper we demonstrate how Compressive Sensing (CS) can be used in pulse-Doppler radars to improve the Doppler performance while preserving range resolution. We investigate here two types of stepped frequency waveforms, the coherent frequency bursts and successive frequency ramps, which can be

  8. Correlation between Spectral Index and Doppler Factor for a ...

    Indian Academy of Sciences (India)

    Abstract. Relativistic beaming effect is important for blazars. In a very recent work, γ-ray Doppler factors were calculated for a sample of Fermi blazars (Fan et al. 2013). In this work, we investigated the correlation between the Doppler factor and the effective spectral index, αOX, and found an anticorrelation between them.

  9. Optical Doppler tomography based on a field programmable gate array

    DEFF Research Database (Denmark)

    Larsen, Henning Engelbrecht; Nilsson, Ronnie Thorup; Thrane, Lars

    2008-01-01

    We report the design of and results obtained by using a field programmable gate array (FPGA) to digitally process optical Doppler tomography signals. The processor fits into the analog signal path in an existing optical coherence tomography setup. We demonstrate both Doppler frequency and envelope...

  10. Normal Foetal Middle Cerebral Arteries Doppler Velocimetry; Study ...

    African Journals Online (AJOL)

    Doppler assessment of the middle cerebral artery (MCA) is one method of evaluating foetus before delivery and can determine foetuses at risk in high risk pregnancies. This study was done to determine the normal reference values of foetal middle cerebral artery Doppler indices in our population. One hundred and forty ...

  11. Correlation between Spectral Index and Doppler Factor for a ...

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Relativistic beaming effect is important for blazars. In a very recent work, -ray Doppler factors were calculated for a sample of Fermi blazars (Fan et al. 2013). In this work, we investigated the correlation between the Doppler factor and the effective spectral index, 4OX, and found an anticorrelation ...

  12. The effectiveness of Doppler controlled hemorrhoidal artery ligation ...

    African Journals Online (AJOL)

    In this work, we discuss the preliminary results of the effectiveness of the hemorrhoidal artery ligation under control Doppler as a new technique for the treatment of hemorrhoids. We report the results of patients with hemorrhoids we have followed over a period of one year who were treated with HAL Doppler. The intra-and ...

  13. Measurement of depth of burns by laser Doppler perfusion imaging

    NARCIS (Netherlands)

    Droog, E.J.; Droog, E.J.; Steenbergen, Wiendelt; Sjöberg, F.

    2001-01-01

    Laser Doppler perfusion imaging (LDPI), is a further development in laser Doppler flowmetry (LDF). Its advantage is that it enables assessment of microvascular blood flow in a predefined skin area rather than, as for LDF, in one place. In many ways this method seems to be more promising than LDF in

  14. "An analysis of the classical Doppler Effect"[1] revisited

    OpenAIRE

    Rothenstein, Bernhard; Nafornita, Corina

    2004-01-01

    After having shown that the formula which describes the Doppler effect in the general case holds only in the case of the "very high" frequency assumption, we derive free of assumptions Doppler formulas for two scenarios presented in the revisited paper.

  15. Doppler weather radar with predictive wind shear detection capabilities

    Science.gov (United States)

    Kuntman, Daryal

    1991-01-01

    The status of Bendix research on Doppler weather radar with predictive wind shear detection capability is given in viewgraph form. Information is given on the RDR-4A, a fully coherent, solid state transmitter having Doppler turbulence capability. Frequency generation data, plans, modifications, system characteristics and certification requirements are covered.

  16. Methodology for obtaining wind gusts using Doppler lidar

    DEFF Research Database (Denmark)

    Suomi, Irene; Gryning, Sven-Erik; O'Connor, Ewan J.

    2017-01-01

    A new methodology is proposed for scaling Doppler lidar observations of wind gusts to make them comparable with those observed at a meteorological mast. Doppler lidars can then be used to measure wind gusts in regions and heights where traditional meteorological mast measurements are not availabl...

  17. Micro-Doppler classification of riders and riderless horses

    Science.gov (United States)

    Tahmoush, David

    2014-05-01

    Micro-range Micro-Doppler can be used to isolate particular parts of the radar signature, and in this case we demonstrate the differences in the signature between a walking horse versus a walking horse with a rider. Using micro-range micro-Doppler, we can distinguish the radar returns from the rider as separate from the radar returns of the horse.

  18. An elementary approach to the gravitational Doppler shift

    Science.gov (United States)

    Wörner, C. H.; Rojas, Roberto

    2017-01-01

    In college physics courses, treatment of the Doppler effect is usually done far from the first introduction to kinematics. This paper aims to apply a graphical treatment to describe the gravitational redshift, by considering the Doppler effect in two accelerated reference frames and exercising the equivalence principle. This approach seems appropriate to discuss with beginner students and could serve to enrich the didactic processes.

  19. Umbilical artery doppler velocimetry study on prediction of adverse ...

    African Journals Online (AJOL)

    Background: Doppler velocimetry studies of pregnant women with diabetes mellitus can predict adverse pregnancy outcomes. Objective: To identify pregnant women with diabetes mellitus for second trimester umbilical artery Doppler velocimetry to predict adverse pregnancy outcomes. Methods: It was a prospective study ...

  20. Experience in scrotal doppler ultrasound in a Nigerian tertiary hospital

    African Journals Online (AJOL)

    Background: Scrotal diseases can be diagnosed with clinical examination or radiological imaging. The use of ultrasound with Doppler application has several advantages in the evaluation of this sensitive and private organ. Objectives: To document the pattern of Doppler ultrasound findings in patients presenting with ...

  1. Comparison between Doppler Ultrasound and Biopsy Findings in ...

    African Journals Online (AJOL)

    Methods: We retrospectively studied a random sample of 188 kidney transplanted patients who had Doppler-ultrasound examination followed within two weeks by transplant biopsy. We evaluated the specificity and sensitivity of Doppler ultrasound in diagnosing rejection at different RI thresholds, using the reported biopsy ...

  2. The value of Doppler ultrasound in cirrhosis and portal hypertension

    NARCIS (Netherlands)

    Kok, T.; van der Jagt, E. J.; Haagsma, E. B.; Bijleveld, C. M.; Jansen, P. L.; Boeve, W. J.

    1999-01-01

    Cirrhosis and portal hypertension affect the flow profile of the liver vasculature. In these conditions Doppler ultrasound can provide important information on the hemodynamics of the portal venous system, the hepatic artery and the hepatic veins. The value of Doppler ultrasound in the assessment of

  3. Sub-Doppler tunable far-infrared spectroscopy

    Science.gov (United States)

    Inguscio, M.; Zink, L. R.; Evenson, K. M.; Jennings, D. A.

    1987-01-01

    The first experimental observations of sub-Doppler linewidths in a cell made using tunable far-infrared radiation are reported. A double-resonance scheme has been used, combining CO2-laser infrared radiation with tunable far-infrared radiation to observe a sub-Doppler line shape in an excited vibrational state of CH3OH.

  4. Musculoskeletal colour/power Doppler in sports medicine

    DEFF Research Database (Denmark)

    Boesen, M I; Boesen, M; Langberg, Henning

    2010-01-01

    This review article discusses the aspects of sports medicine where musculoskeletal Doppler ultrasound has valuable contribution in diagnosis and/or treatment of some of the typical musculoskeletal sports injuries. Also, conditions where the Doppler ultrasound has no value are discussed. Some...

  5. Single-layer closure of typhoid enteric perforation: Our experience ...

    African Journals Online (AJOL)

    Background: Typhoid enteritis is rare in developed countries. The increasing prevalence of typhoid fever with enteric perforation in our environment is alarming. Peritonitis follows enteric perforation due to typhoid enteritis. Surgical treatments and repair of the perforated areas due to typhoid enteritis varies between ...

  6. Doplerovi brodski navigacioni brzinomjeri / Maritime navigational Doppler logs

    Directory of Open Access Journals (Sweden)

    Milovan Unković

    2006-01-01

    Full Text Available Doplerovi navigacioni brodski brzinomjeri rade na principu Doplerovog efekta. Doplerov predajni projektor emituje snop ultrazvučnih vibracija u vodi, a drugi (ili isti projektor prima odbijeni signal od dna ili od sloja vode. U ovom radu opisana je teorija Doplerovog efekta, primjena te teorije na brodskim brzinomjerima, konstrukcija i karakteristike savremenih Doplerovih brzinomjera. / The Doppler maritime navigational logs are based on measurement of the Doppler effect. A Doppler log transmitting transducer emits beam of sound vibration in the water, and a second (or the same transducer receives the echo from the sea bed or -water layer. In this article describes theory of Doppler effect, using this theory in maritime logs, construction and performance of modern Doppler logs.

  7. Use of GPS network data for HF Doppler measurements interpretation

    CERN Document Server

    Petrova, Inna R; Latypov, Ruslan R

    2014-01-01

    The method of measurement of Doppler frequency shift of ionospheric signal - HF Doppler technique - is one of well-known and widely used methods of ionosphere research. It allows to research various disturbances in the ionosphere. There are some sources of disturbances in the ionosphere. These are geomagnetic storms, solar flashes, metrological effects, atmospheric waves. This method allows to find out the influence of earthquakes, explosions and other processes on the ionosphere, which occur near to the Earth. HF Doppler technique has the high sensitivity to small frequency variations and the high time resolution, but interpretation of results is difficult. In this work we make an attempt to use GPS data for Doppler measurements interpretation. Modeling of Doppler frequency shift variations with use of TEC allows to separate ionosphere disturbances of medium scale.

  8. Embolic Doppler ultrasound signal detection via fractional Fourier transform.

    Science.gov (United States)

    Gençer, Merve; Bilgin, Gökhan; Aydın, Nizamettin

    2013-01-01

    Computerized analysis of Doppler ultrasound signals can aid early detection of asymptomatic circulating emboli. For analysis, physicians use informative features extracted from Doppler ultrasound signals. Time -frequency analysis methods are useful tools to exploit the transient like signals such as Embolic signals. Detection of discriminative features would be the first step toward automated analysis of embolic Doppler ultrasound signals. The most problematic part of setting up emboli detection system is to differentiate embolic signals from confusing similar wave-like patterns such as Doppler speckle and artifacts caused by tissue movement, probe tapping, speaking etc. In this study, discrete version of fractional Fourier transform is presented as a solution in the detection of emboli in digitized Doppler ultrasound signals. An accurate set of parameters are extracted using short time Fourier transform and fractional Fourier transform and the results are compared to reveal detection quality. Experimental results prove the efficiency of fractional Fourier transform in which discriminative features becomes more evident.

  9. One way Doppler extractor. Volume 1: Vernier technique

    Science.gov (United States)

    Blasco, R. W.; Klein, S.; Nossen, E. J.; Starner, E. R.; Yanosov, J. A.

    1974-01-01

    A feasibility analysis, trade-offs, and implementation for a One Way Doppler Extraction system are discussed. A Doppler error analysis shows that quantization error is a primary source of Doppler measurement error. Several competing extraction techniques are compared and a Vernier technique is developed which obtains high Doppler resolution with low speed logic. Parameter trade-offs and sensitivities for the Vernier technique are analyzed, leading to a hardware design configuration. A detailed design, operation, and performance evaluation of the resulting breadboard model is presented which verifies the theoretical performance predictions. Performance tests have verified that the breadboard is capable of extracting Doppler, on an S-band signal, to an accuracy of less than 0.02 Hertz for a one second averaging period. This corresponds to a range rate error of no more than 3 millimeters per second.

  10. Abnormal portal vein waveform as an indicator of constrictive pericarditis – a case report

    Directory of Open Access Journals (Sweden)

    Joanna Ścieszka

    2015-06-01

    Full Text Available We report a case of a 17-year-old patient referred to our outpatient Doppler Department due to clinical suspicion of liver cirrhosis. The patient presented with non-specifi c symptoms, such as malaise, pain in the right subcostal region, peripheral oedema. Until then, diagnostic imaging, including echocardiography was inconclusive. We performed the Doppler sonography of the portal system, which revealed normal diameter of the portal vein with abnormal, phasic and markedly pulsatile waveform. Hepatic veins distention with pathological reverse fl ow during systole was reported. Additionally, inferior vena cava was dilated and remained unchanged through the respiratory cycle. Basing on the above image a heart disease, which had not been taken into differential diagnosis before, was suggested. The following echocardiography, together with computed tomography, enabled a diagnosis of constrictive pericarditis. Successful pericardiotomy was performed. Such a complicated diagnostics happened to demonstrate an uncommon example of the use of portal vein waveform in making the proper cardiologic diagnosis.

  11. Abnormal shortened diastolic time length at increasing heart rates in patients with abnormal exercise-induced increase in pulmonary artery pressure

    Directory of Open Access Journals (Sweden)

    Bombardini Tonino

    2011-11-01

    Full Text Available Abstract Background The degree of pulmonary hypertension is not independently related to the severity of left ventricular systolic dysfunction but is frequently associated with diastolic filling abnormalities. The aim of this study was to assess diastolic times at increasing heart rates in normal and in patients with and without abnormal exercise-induced increase in pulmonary artery pressure (PASP. Methods. We enrolled 109 patients (78 males, age 62 ± 13 years referred for exercise stress echocardiography and 16 controls. The PASP was derived from the tricuspid Doppler tracing. A cut-off value of PASP ≥ 50 mmHg at peak stress was considered as indicative of abnormal increase in PASP. Diastolic times and the diastolic/systolic time ratio were recorded by a precordial cutaneous force sensor based on a linear accelerometer. Results At baseline, PASP was 30 ± 5 mmHg in patients and 25 ± 4 in controls. At peak stress the PASP was normal in 95 patients (Group 1; 14 patients (Group 2 showed an abnormal increase in PASP (from 35 ± 4 to 62 ± 12 mmHg; P Conclusion The first and second heart sound vibrations non-invasively monitored by a force sensor are useful for continuously assessing diastolic time during exercise. Exercise-induced abnormal PASP was associated with reduced diastolic time at heart rates beyond 100 beats per minute.

  12. EVALUATING MORTALITY RATE CAUSED BY ELECTROLYTE ABNORMALITIES IN PATIENTS HOSPITALIZED

    Directory of Open Access Journals (Sweden)

    B. Khorasani

    2008-05-01

    Full Text Available Adjustment of composition of body fluids and electrolytes is one of the most important aspects of patients care. Sodium and Potassium are the most important body cations, the improper adjustment of them will cause sever disorders in neuromuscular, gastrointestinal, respiratory and cardiovascular systems. Acute renal failure indicated by increase in creatinine and nitrogen urea, brings an accumulation of fluids, salts and metabolites of nitrogen in body. This study intends to assess the status of electrolyte abnormalities and mortality rates of the patients hospitalized in ICU wards in our country. This is a descriptive and retrospective study on the records of 378 patients hospitalized in ICU. A questionnaire was prepared and the data were entered in SPSS system. They were statistically analyzed by using chi-square and fisher's Exact test methods. Out of 378 patients hospitalized in ICU, over 2/3 of them were male and over half of them were>45 years old. Frequency distribution of electrolyte abnormalities was as follows: Hyponatremia 59% hypernatremia 23% hypokalemia 37% hyperkalemia 28%, 35% and 21% of patients had respectively BUN and creatinine more than the normal range. 26% of patients hospitalized in ICU had nonsurgical problems and 74% of the patients had surgical problems. Average time of hospitalization in ICU was 85 days and mortality rate was 35%. The most common electrolyte abnormality was related to variation in serum sodium levels in the form of hyponatremia. And the highest prevalence electrolyte abnormality in dead patients was hyponatremia. This study proves that the prevalence of electrolyte abnormalities is directly related to mortality and increase in hospitalization period and those having undergone surgical operations during hospitalization in ICU, manifested more abnormalities.

  13. Abnormal glucose tolerance and lipid abnormalities in Indian ...

    African Journals Online (AJOL)

    quency of abnormal glucose tolerance (impaired glucose tole- rance and diabetes mellitus) in Indian patients with CAD is similar to that in White patients.9 However, with respect to the lipid profile there have been conflicting reports; hypercholeste- rolaemia was present in 37% ofthe series described by McKech- nie' and ...

  14. Chromagen lenses and abnormal colour perception

    Directory of Open Access Journals (Sweden)

    O. Matthew Oriowo

    2011-12-01

    Full Text Available Background: The Chromagen lens system comprises of tinted spectacle or contact lenses, each with a specific colour wavelength filter which controls the spectra of the light entering the eye. This study investigated whether spectacle-mounted Chromagen lenses would enhance colour perception in individuals with abnormal colour vision.Methods: The Ishihara colour test was used to test for colour vision deficiency (CVD and also to evaluate the effect of the Chromagen spectacle lens on colour perception in 13 subjects. An Oculus Anomaloscope was used to confirm and sub-classify the types of CVD. Subjects comprised of school age children from the Riyadh area in Saudi Arabia.Results: The distribution amongst the male participants comprised two subjects with protanomaly, two with protanopia, five with deuteranomaly, and two with deuteranopia. Amongst the two female participants, one subject showed deuteranomaly, and one showed protanomaly. Different types of Chromagen spectacle lenses displayed some levels of colour vision enhancement depending on type of CVD.Conclusion: The findings support the notion that chromagen lenses could enhance colour vision perception in some cases of red-green colour vision defects. Clients with CVD should be managed on an individual case basis. (S Afr Optom 2011 70(2 69-74 

  15. Longitudinal microvascularity in achilles tendinopathy (power doppler ultrasound, magnetic resonance imaging time-intensity curves and the Victorian Institute of Sport Assessment-Achilles questionnaire): a pilot study

    Energy Technology Data Exchange (ETDEWEB)

    Richards, Paula J. [University Hospital of North Staffordshire NHS Trust (UHNS), Stoke on Trent, Staffordshire (United Kingdom); Keele University, Keele, Staffordshire (United Kingdom); North Staffs. Royal Infirmary, X-ray Department, Stoke on Trent, Staffordshire (United Kingdom); McCall, Iain W. [Keele University, Keele, Staffordshire (United Kingdom); North Staffordshire NHS Trust, Stoke on Trent, Staffordshire (United Kingdom); Day, Christopher [University Hospital of North Staffordshire NHS Trust (UHNS), Stoke on Trent, Staffordshire (United Kingdom); Belcher, John [Cardiff University, Department of Primary Care and Public Health, North Wales Clinical School, Cardiff (United Kingdom); Maffulli, Nicola [Keele University, Keele, Staffordshire (United Kingdom)

    2010-06-15

    To evaluate the imaging of the natural history of Achilles tendinopathy microvascularisation in comparison with symptoms, using a validated disease-specific questionnaire [the Victorian Institute of Sport Assessment-Achilles (VISA-A)]. A longitudinal prospective pilot study of nine patients with post-contrast magnetic resonance imaging (MRI), time-intensity curve (TIC) enhancement, ultrasound (US) and power Doppler (PD) evaluation of tendinopathy of the mid-Achilles tendon undergoing conservative management (eccentric exercise) over 1 year. There were five men and four women [mean age 47 (range 30-62) years]. Six asymptomatic tendons with normal US and MRI appearance showed less enhancement than the tibial metaphysis did and showed a flat, constant, but very low rate of enhancement in the bone and Achilles tendon (9-73 arbitrary TIC units). These normal Achilles tendons on imaging showed a constant size throughout the year (mean 4.9 mm). At baseline the TIC enhancement in those with tendinopathy ranged from 90 arbitrary units to 509 arbitrary units. Over time, 11 abnormal Achilles tendons, whose symptoms settled, were associated with a reduction in MRI enhancement mirrored by a reduction in the number of vessels on power Doppler (8.0 to 2.7), with an improvement in morphology and a reduction in tendon size (mean 15-10.6 mm). One tendon did not change its abnormal imaging features, despite improving symptoms. Two patients developed contralateral symptoms and tendinopathy, and one had more abnormal vascularity on power Doppler and higher MRI TIC peaks in the asymptomatic side. In patient with conservatively managed tendinopathy of the mid-Achilles tendon over 1 year there was a reduction of MRI enhancement and number of vessels on power Doppler, followed by morphological improvements and a reduction in size. Vessels per se related to the abnormal morphology and size of the tendon rather than symptoms. Symptoms improve before the Achilles size reduces and the

  16. Endoscopic solutions to challenging enteral feeding problems.

    Science.gov (United States)

    Paski, Shirley C; Dominitz, Jason A

    2012-09-01

    Enteral nutrition support is often required in patients who are unable to meet their own nutritional requirements. Endoscopists play a key role in the placement of enteral feeding catheters. This review focuses on the recently published solutions to common problems encountered during endoscopic placement of enteral feeding devices. Case reports and case series describe solutions for overcoming common problems encountered during the placement of enteral feeding devices. Transnasal techniques can simplify nasojejunal tube placement, whereas deep enteroscopy techniques provide more reliable jejunostomy placement. Endoscopic ultrasound can help when transillumination is not possible or in the setting of postsurgical anatomy like Roux-en-Y. Laparoscopic-assisted procedures are useful when endoscopic techniques have failed in adults or in select high-risk pediatric patients. The American Society for Gastrointestinal Endoscopy and the American Gastroenterology Association both published comprehensive guidelines that outline the indications, contraindications, technical aspects of feeding catheter placement, and complications. Advances in endoscopic techniques, including deep enteroscopy, endoscopic ultrasound, ultra-slim transnasal endoscopes and laparoscopic-assisted procedures, have enabled endoscopists to successfully place enteral feeding tubes in patients who previously required open procedures.

  17. Achilles tendon (TA) size and power Doppler ultrasound (PD) changes compared to MRI: A preliminary observational study

    Energy Technology Data Exchange (ETDEWEB)

    Richards, P.J.; Dheer, A.K.; McCall, I.M

    2001-10-01

    AIM: To assess whether abnormal Achilles tendon (TA) magnetic resonance imaging (MRI) and spectral ultrasound (US) features have associated development of microvascular power Doppler (PD) flow. MATERIALS AND METHODS: In a prospective, controlled and blinded study six patients with TA symptoms were compared to five with other ankle abnormalities. Two radiologists independently measured the mean maximal anteroposterior diameter on MRI and conventional US (categorized as normal <6 mm, mild 6.1-10 mm, moderate 1.1-1.5 cm and severely enlarged > 1.6 cm), assessed morphology and studied the vessels using power Doppler. They formed a consensus over discrepancies. Sonography of the contralateral side within 24 h was used as a control. RESULTS: Twenty-one tendons in six women and five men, aged 45-77 years (mean 57.6 years), were examined, 12 tendons were of normal US morphology and size (<6 mm), and did not exhibit PD's flow (interobserver agreement K > 0.74). Of the 12 tendons studied by MRI five were normal, seven tendons were enlarged, five of which had a proportionate increase in PD flow at the margin on the deep surface and four also had vessels in the centre of the tendon. All five of these tendons had high signal on T2-weighting (T2W). Of the two mildly enlarged tendons of intermediate signal on T1 and T2W, one showed PD flow and the other did not. CONCLUSIONS: In patients with TA disease power Doppler ultrasound shows proliferation of vessels in enlarged, abnormal tendons demonstrated on MRI and standard ultrasound, in the absence of definite tears. Richards, P.J. Dheer, A.K. and McCall, I.M. (2001)

  18. Microscale Heat Conduction Models and Doppler Feedback

    Energy Technology Data Exchange (ETDEWEB)

    Hawari, Ayman I. [North Carolina State Univ., Raleigh, NC (United States); Ougouag, Abderrafi [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-01-22

    The objective of this project is to establish an approach for providing the fundamental input that is needed to estimate the magnitude and time-dependence of the Doppler feedback mechanism in Very High Temperature reactors. This mechanism is the foremost contributor to the passive safety of gas-cooled, graphite-moderated high temperature reactors that use fuel based on Tristructural-Isotropic (TRISO) coated particles. Therefore, its correct prediction is essential to the conduct of safety analyses for these reactors. Since the effect is directly dependent on the actual temperature reached by the fuel during transients, the underlying phenomena of heat deposition, heat transfer and temperature rise must be correctly predicted. To achieve the above objective, this project will explore an approach that accounts for lattice effects as well as local temperature variations and the correct definition of temperature and related local effects.

  19. Vibration-free Raman Doppler velocimeter

    Science.gov (United States)

    Exton, R. J.

    1986-11-01

    A method and apparatus unaffected by vibrational environments for obtaining measurements using Raman Doppler Velocimetry is described. Two laser beams, a pump beam, and a probe beam, are focused by a lens to a point in a flow. A lens collimates the two beams. A beam splitter dumps the beam and the other beam is reflected by a corner cube back to the lens. The other lens then focuses the beam back to the point. The reflected beam and the backward and forward scattering at the point are detected by a detector and processed by a boxcar averager. The lens and corner cube combination, called a retrometer, ensure that the measurements are unaffected by vibrations.

  20. Early Doppler studies in lupus pregnancy.

    Science.gov (United States)

    Kerslake, S; Morton, K E; Versi, E; Buchanan, N M; Khamashta, M; Baguley, E; Braude, P; Hughes, G R

    1992-01-01

    The management of 56 pregnancies in 54 patients is presented, 52 with systemic lupus erythematosus and two patients with primary antiphospholipid syndrome. All underwent serial Doppler blood flow studies of the umbilical and uterine arteries from 14 weeks of gestation. Drug therapy was directed at disease activity and the fetus and mother monitored intensively to identify optimum time for delivery. End diastolic blood flow (EDF) studies were compared with anticardiolipin antibodies (aCL) and the lupus anticoagulant (LAC) to predict outcome of pregnancy in terms of mortality, Caesarian delivery, hypertension, and gestation. The absence of end-diastolic blood flow predicted Caesarian delivery more accurately. The presence of EDF and the absence of aCL was consistent with a normotensive pregnancy. The presence of LAC was the best of the three in predicting fetal demise.

  1. Widefield laser doppler velocimeter: development and theory.

    Energy Technology Data Exchange (ETDEWEB)

    Hansche, Bruce David; Reu, Phillip L.; Massad, Jordan Elias

    2007-03-01

    The widefield laser Doppler velocimeter is a new measurement technique that significantly expands the functionality of a traditional scanning system. This new technique allows full-field velocity measurements without scanning, a drawback of traditional measurement techniques. This is particularly important for tests in which the sample is destroyed or the motion of the sample is non-repetitive. The goal of creating ''velocity movies'' was accomplished during the research, and this report describes the current functionality and operation of the system. The mathematical underpinnings and system setup are thoroughly described. Two prototype experiments are then presented to show the practical use of the current system. Details of the corresponding hardware used to collect the data and the associated software to analyze the data are presented.

  2. Pulsed laser Doppler measurements of wind shear

    Science.gov (United States)

    Dimarzio, C.; Harris, C.; Bilbro, J. W.; Weaver, E. A.; Burnham, D. C.; Hallock, J. N.

    1979-01-01

    There is a need for a sensor at the airport that can remotely detect, identify, and track wind shears near the airport in order to assure aircraft safety. To determine the viability of a laser wind-shear system, the NASA pulsed coherent Doppler CO2 lidar (Jelalian et al., 1972) was installed in a semitrailer van with a rooftop-mounted hemispherical scanner and was used to monitor thunderstorm gust fronts. Wind shears associated with the gust fronts at the Kennedy Space Center (KSC) between 5 July and 4 August 1978 were measured and tracked. The most significant data collected at KSC are discussed. The wind shears were clearly visible in both real-time velocity vs. azimuth plots and in postprocessing displays of velocities vs. position. The results indicate that a lidar system cannot be used effectively when moderate precipitation exists between the sensor and the region of interest.

  3. Doppler time-of-flight imaging

    KAUST Repository

    Heidrich, Wolfgang

    2017-02-16

    Systems and methods for imaging object velocity are provided. In an embodiment, at least one Time-of-Flight camera is used to capture a signal representative of an object in motion over an exposure time. Illumination and modulation frequency of the captured motion are coded within the exposure time. A change of illumination frequency is mapped to measured pixel intensities of the captured motion within the exposure time, and information about a Doppler shift in the illumination frequency is extracted to obtain a measurement of instantaneous per pixel velocity of the object in motion. The radial velocity information of the object in motion can be simultaneously captured for each pixel captured within the exposure time. In one or more aspects, the illumination frequency can be coded orthogonal to the modulation frequency of the captured motion. The change of illumination frequency can correspond to radial object velocity.

  4. Laser Doppler vibrometer employing active frequency feedback.

    Science.gov (United States)

    Chijioke, Akobuije; Lawall, John

    2008-09-20

    We present a heterodyne Michelson interferometer for vibration measurement in which feedback is used to obviate the need to unwrap phase data. The Doppler shift of a vibrating target mirror is sensed interferometrically and compensated by means of a voltage-controlled oscillator driving an acousto-optic modulator. For frequencies within the servo bandwidth, the oscillator control voltage provides a direct measurement of the target velocity. Outside the servo bandwidth, phase-sensitive detection is used to evaluate high-frequency displacements. This approach is of great interest for the frequently-occurring situation where vibration amplitudes at low frequency exceed an optical wavelength, but knowledge of the vibration spectrum at high frequency is important as well.

  5. Analytic radar micro-Doppler signatures classification

    Science.gov (United States)

    Oh, Beom-Seok; Gu, Zhaoning; Wang, Guan; Toh, Kar-Ann; Lin, Zhiping

    2017-06-01

    Due to its capability of capturing the kinematic properties of a target object, radar micro-Doppler signatures (m-DS) play an important role in radar target classification. This is particularly evident from the remarkable number of research papers published every year on m-DS for various applications. However, most of these works rely on the support vector machine (SVM) for target classification. It is well known that training an SVM is computationally expensive due to its nature of search to locate the supporting vectors. In this paper, the classifier learning problem is addressed by a total error rate (TER) minimization where an analytic solution is available. This largely reduces the search time in the learning phase. The analytically obtained TER solution is globally optimal with respect to the classification total error count rate. Moreover, our empirical results show that TER outperforms SVM in terms of classification accuracy and computational efficiency on a five-category radar classification problem.

  6. Laser Doppler flowmetry in manual medicine research.

    Science.gov (United States)

    Zegarra-Parodi, Rafael; Snider, Eric J; Park, Peter Yong Soo; Degenhardt, Brian F

    2014-12-01

    Laser Doppler flowmetry (LDF) is commonly used in combination with reactivity tests to noninvasively evaluate skin sympathetic nerve activity and skin microvascular function. In manual medicine research, LDF has been used as a marker for global peripheral sympathetic nervous system function, but these results should be considered with caution because skin sympathetic nerve activity physiology is often overlooked. Another limitation of LDF in manual medicine research is the processing of LDF recordings. Two methods have been suggested: the time-domain analysis and the frequency-domain analysis. Standardization is required for data collection and processing in either domain to accurately interpret these changes in skin blood flow that occur after manual procedures. For physiologic studies using LDF, the authors recommend the use of noninvasive reactivity tests (positive controls) to evaluate the different mechanisms involved in overall skin blood flow changes and to compare the magnitude of these changes with those specifically elicited by manual procedures. © 2014 The American Osteopathic Association.

  7. Phase Doppler anemometry as an ejecta diagnostic

    Science.gov (United States)

    Bell, D. J.; Chapman, D. J.

    2017-01-01

    When a shock wave is incident on a free surface, micron sized pieces of the material can be ejected from that surface. Phase Doppler Anemometry (PDA) is being developed to simultaneously measure the sizes and velocities of the individual shock induced ejecta particles; providing an important insight into ejecta phenomena. The results from experiments performed on the 13 mm bore light gas gun at the Institute of Shock Physics, Imperial College London are presented. Specially grooved tin targets were shocked at pressures of up to 14 GPa, below the melt on release pressure, to generate ejecta particles. These experiments are the first time that PDA has been successfully fielded on dynamic ejecta experiments. The results and current state of the art of the technique are discussed along with the future improvements required to optimise performance and increase usability.

  8. The Christian Doppler Laboratory on Contextual Interfaces

    Science.gov (United States)

    Grill, Thomas; Reitberger, Wolfgang; Obrist, Marianna; Meschtscherjakov, Alexander; Tscheligi, Manfred

    Contextual interfaces gain more and more importance within the last years. Numerous research programs that address the term context have been established, each focusing on context from their own point of view. The Christian Doppler Laboratory on Contextual Interfaces has been founded with different goals in mind. The first goal is to elaborate on the definitions and foundations of the term context to achieve a common understanding on how to use context and the terms related to context. Further we elaborate on the relation between context and user experience to tackle the complexity of the interrelations between both areas. The second goal is to apply the findings of the basic context research with two different context laboratories, each addressing a different application area. This allows to build a robust research basis that is applied to application oriented research.

  9. Molecular survey of enteric viruses in commercial chicken farms in Korea with a history of enteritis.

    Science.gov (United States)

    Koo, B S; Lee, H R; Jeon, E O; Han, M S; Min, K C; Lee, S B; Mo, I P

    2013-11-01

    Several enteric viruses have increasingly received attention as potential causative agents of runting-stunting syndrome (RSS) in chickens. A molecular survey was performed to determine the presence of a broad range of enteric viruses, namely chicken astrovirus (CAstV), avian nephritis virus (ANV), chicken parvovirus (ChPV), infectious bronchitis virus (IBV), avian rotavirus (AvRV), avian reovirus (ARV), and fowl adenovirus (FAdV), in intestinal samples derived from 34 commercial chicken flocks that experienced enteritis outbreaks between 2010 and 2012. Using techniques such as PCR and reverse-transcription PCR, enteric viruses were identified in a total of 85.3% of investigated commercial chicken flocks in Korea. Furthermore, diverse combinations of 2 or more enteric viruses were simultaneously identified in 51.7% of chicken farms positive for enteric viruses. The rank order of positivity for enteric viruses was as follows: ANV (44.1%), CAstV (38.2%), ChPV (26.5%), IBV (20.6%), ARV (8.8%), AvRV (5.9%), and FAdV (2.9%). Additionally, other pathogens such as Escherichia coli, Salmonella spp., Eimeria spp., and FAdV were detected in 79% of chicken flocks positive for enteric viruses using PCR, bacterial isolation, and microscopic examination. The results of our study indicate the presence of several enteric viruses with various combinations in commercial chicken farms that experienced enteritis outbreaks. Experimental studies are required to further understand the roles of enteric viruses in RSS in commercial chickens.

  10. Acute cerebellar ataxia in enteric fever.

    Science.gov (United States)

    Sawhney, I M; Prabhakar, S; Dhand, U K; Chopra, J S

    1986-01-01

    Acute cerebellar ataxia as an isolated neurological manifestation of enteric fever is very rare. Three cases of acute cerebellar ataxia associated with enteric fever are reported. The diagnosis of enteric fever was confirmed by positive blood culture, strongly positive Widal test and rising antibody titres. The major clinical features were rapid development of gait ataxia, limb ataxia and dysarthria. None of the patients had altered sensorium. The cerebellar involvement was noticed on the second or third day of fever which progressed for one to two days. The symptoms remained static for one to two weeks and thereafter all the patients showed gradual recovery in a few weeks. Acute onset of cerebellar lesion, self limiting course and cerebrospinal fluid pleocytosis suggest par- or post-infectious demyelinating pathology in these patients, who were not related to each other.

  11. Pneumatosis intestinalis associated with enteral tube feeding.

    Science.gov (United States)

    Zorgdrager, Marcel; Pol, Robert

    2013-12-03

    A 49-year-old man presented with a Hinchey II perforated diverticulitis and underwent laparoscopic peritoneal lavage. During the postoperative course the patient received enteral tube feeding which was followed by a bowel obstruction accompanied with pneumatosis intestinalis (PI). Explorative laparotomy showed an omental band adhesion without signs of ischaemia. After a short period of total parenteral nutrition PI resolved almost completely and enteral tube feeding could be continued once again. In the weeks that followed the patient developed atypical bowel symptoms and recurrent PI which resolved each time the drip feeding was discontinued. Despite the mild clinical course, a CT scan showed massive PI on day 21 after the laparotomy. After excluding life-threatening conditions conservative management was instituted and the patient recovered completely after discontinuing the drip feeding. We present one of the few cases of subclinical PI associated with enteral tube feeding that could be managed conservatively.

  12. Advances in transcranial Doppler clinical applications.

    Science.gov (United States)

    Topcuoglu, Mehmet Akif; Unal, Ali; Arsava, Ethem Murat

    2010-07-01

    Diagnostic neurosonology techniques including transcranial Doppler (TCD), transcranial color Doppler imaging (TCDI) and power motion-mode (PMD) TCD provide information about various aspects of cerebrovascular status such as microemboli detection, dynamic autoregulation and long-duration real-time monitoring of flow characteristics. Although most of the information provided cannot be obtained by any other imaging methodology, and is critical in clinical decision-making in the care of various neurovascular diseases, these modalities are widely underutilized. Increasing the familiarity to neurosonological techniques is of crucial importance. After briefly reviewing TCD, TCDI and PMD techniques, classical features are summarized and recent developments in the clinical neurosonology applications with specific interest in the neurovascular disorders. Practical perspectives of ultrasound evaluation of intracranial arterial status in various neurovascular diseases including sickle cell vasculopathy and vasospasm are reviewed in detail. Pearls on the neurosonological monitoring of acute ischemic stroke and increased intracranial pressure increase is provided. Standards of cerebral microembolism detection, right to left shunts diagnosis and cerebral autoregulation assessment are discussed methodologically. Future perspectives of therapeutic neurosonology including sonothrombolysis, microbubble-ultrasound-mediated gene and drug delivery into the brain, and alteration of the brain-blood barrier permeability are summarized. Suitable with future medicine, neurosonology brings imaging to the bedside, which enables the treating physician to monitor a given intervention in real time. A non-invasive neurosonology-guided treatment of various diseases could be possible in the near future. The first and foremost step in gaining mastery in this very fruitful field is beginning to use it.

  13. Laser Doppler flowmetry in endodontics: a review.

    Science.gov (United States)

    Jafarzadeh, H

    2009-06-01

    Vascular supply is the most accurate marker of pulp vitality. Tests for assessing vascular supply that rely on the passage of light through a tooth have been considered as possible methods for detecting pulp vitality. Laser Doppler flowmetry (LDF), which is a noninvasive, objective, painless, semi-quantitative method, has been shown to be reliable for measuring pulpal blood flow. The relevant literature on LDF in the context of endodontics up to March 2008 was reviewed using PubMed and MEDLINE database searches. This search identified papers published between June 1983 and March 2008. Laser light is transmitted to the pulp by means of a fibre optic probe. Scattered light from moving red blood cells will be frequency-shifted whilst that from the static tissue remains unshifted. The reflected light, composed of Doppler-shifted and unshifted light, is returned by afferent fibres and a signal is produced. This technique has been successfully employed for estimating pulpal vitality in adults and children, differential diagnosis of apical radiolucencies (on the basis of pulp vitality), examining the reactions to pharmacological agents or electrical and thermal stimulation, and monitoring of pulpal responses to orthodontic procedures and traumatic injuries. Assessments may be highly susceptible to environmental and technique-related factors. Nonpulpal signals, principally from periodontal blood flow, may contaminate the signal. Because this test produces no noxious stimuli, apprehensive or distressed patients accept it more readily than current methods of pulp vitality assessment. A review of the literature and a discussion of the application of this system in endodontics are presented.

  14. Lentiginosis, Deafness and Cardiac Abnormalities*

    African Journals Online (AJOL)

    1973-01-06

    Jan 6, 1973 ... The familia:l form is milder. The cardiac lesion commonly consists of hypertrophic obstructive cardiomyopathy of either ventricle or abnor- malities of the ECG.' The obstructive lesion may be pro- gressive and cause cardiac failure. The ECG features include conduction abnormalities, such as left hemiblock,.

  15. Chromosomal Abnormalities Associated With Omphalocele

    Directory of Open Access Journals (Sweden)

    Chih-Ping Chen

    2007-03-01

    Full Text Available Fetuses with omphalocele have an increased risk for chromosomal abnormalities. The risk varies with maternal age, gestational age at diagnosis, association with umbilical cord cysts, complexity of associated anomalies, and the contents of omphalocele. There is considerable evidence that genetics contributes to the etiology of omphalocele. This article provides an overview of chromosomal abnormalities associated with omphalocele and a comprehensive review of associated full aneuploidy such as trisomy 18, trisomy 13, triploidy, trisomy 21, 45,X, 47,XXY, and 47,XXX, partial aneuploidy such as dup(3q, dup(11p, inv(11, dup(1q, del(1q, dup(4q, dup(5p, dup(6q, del(9p, dup(15q, dup(17q, Pallister-Killian syndrome with mosaic tetrasomy 12p and Miller-Dieker lissencephaly syndrome with deletion of 17p13.3, and uniparental disomy (UPD such as UPD 11 and UPD 14. Omphalocele is a prominent marker for chromosomal abnormalities. Perinatal identification of omphalocele should alert chromosomal abnormalities and familial unbalanced translocations, and prompt thorough cytogenetic investigations and genetic counseling.

  16. Interpreting chromosomal abnormalities using Prolog.

    Science.gov (United States)

    Cooper, G; Friedman, J M

    1990-04-01

    This paper describes an expert system for interpreting the standard notation used to represent human chromosomal abnormalities, namely, the International System for Human Cytogenetic Nomenclature. Written in Prolog, this program is very powerful, easy to maintain, and portable. The system can be used as a front end to any database that employs cytogenetic notation, such as a patient registry.

  17. Admission haematological abnormalities and postoperative ...

    African Journals Online (AJOL)

    Admission haematological abnormalities and postoperative outcomes in neonates with acute surgical conditions in Alexandria, Egypt. HL Wella, SMM Farahat. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals ...

  18. Enteric alpha defensins in norm and pathology

    Directory of Open Access Journals (Sweden)

    Lisitsyn Nikolai A

    2012-01-01

    Full Text Available Abstract Microbes living in the mammalian gut exist in constant contact with immunity system that prevents infection and maintains homeostasis. Enteric alpha defensins play an important role in regulation of bacterial colonization of the gut, as well as in activation of pro- and anti-inflammatory responses of the adaptive immune system cells in lamina propria. This review summarizes currently available data on functions of mammalian enteric alpha defensins in the immune defense and changes in their secretion in intestinal inflammatory diseases and cancer.

  19. ANALISIS EFEK KECELAKAAN WATER INGRESS TERHADAP REAKTIVITAS DOPPLER TERAS RGTT200K

    Directory of Open Access Journals (Sweden)

    Zuhair Zuhair

    2015-03-01

    melekat dengan cara pasif. Kata kunci: Water ingress, reaktivitas Doppler, RGTT200K   In high temperature reactor, the negative temperature reactivity coefficient guarantees fission reaction in the core remain under the control and decay heat will not melt the fuel which cause the release of radioactive substances into the environment. But the entry of water (water ingress into the reactor core due to rupture of a steam generator tube heat exchanger, which is known as one of the design basis accidents, can introduce positive reactivity with other potential hazards such as graphite corrosion and damage of the reflector structure material. This paper will investigate the effect of water ingress accident on Doppler reactivity coefficient of RGTT200K core. The capability of the Doppler reactivity coefficient to compensate positive reactivity incurred during water ingress accident will be examined through a series of calculations with MCNPX code and ENDF/B-VII library for fuel temperature changes from 800K to 1800K. Three options of UO2, ThO2/UO2 and PuO2 fuel kernels with three lattice models of fuel pebble in the reactor core was applied for condition of water ingress with water density from 0 to 1000 kg/m3. The results of the calculations show that Doppler reactivity coefficient is negative for the entire fuel options being considered even for a large possibility of water ingress. The effects of water ingress becomes stronger in lattice model with lower packing fraction because more volume available for water entering the reactor core. The effect of water ingress is also stronger in the uranium core compared to thorium and plutonium cores as a consequence of the Doppler phenomenon where the neutron absorption in resonance region of 238U is greater than 232Th and 240Pu. It can be concluded overall that Doppler coefficient of RGTT200K core has capability to compensate the reactivity insertion introduced by water ingress accident. RGTT200K core with UO2, ThO2/UO2 and PuO2

  20. Prostate vascular flow: The effect of the ejaculation on the power doppler ultrasonographic examination.

    Science.gov (United States)

    Alonge, S; Melandri, M; Fanciullo, L; Lacalandra, G M; Aiudi, G

    2018-02-01

    Power Doppler sonography (PD) can accurately depict tissue perfusion, recognize slow flows, and is relatively angle independent. The monitoring of local blood flow by Doppler ultrasonography is helpful in differentiating prostatic physio-pathological conditions, but the recognizing of physiological variables that could affect it is crucial to apply this technique in clinical practice. This study aimed to evaluate if ejaculation affects blood flow to the prostate and to state how long this effect lasts. Serial PD examinations of prostate were performed in 18 dogs (1-5 years, 6-40 kg) immediately before (T0) and after (T1) the ejaculation, and repeated 6 (T2), 18 (T3) and 24 (T4) hours later. For each examination, two representative PD images were chosen and ranked by two independent observers according to the following scoring system: 0 = mild subcapsular (S) vascularization without clear evidence of parenchymal (P) vascularization; 1 = moderate P and S vascularization; 2 = severe S and moderate P vascularization; 3 = severe P and moderate S vascularization; 4 = severe P and S vascularization. Interobserver agreement was assessed using Kappa of Cohen. Ranked data, grouped according to time, were compared by ANOVA and Tukey HSD test (p flow pattern at different times were observed for all dogs. The statistical analysis evidenced a significant difference for T0 vs T1 and vs T2 and vs T3 (p  .05). Interobserver agreement was very good (Kappa of Cohen = 0.86). This study demonstrated a definite increase in vascular flow to the prostate after ejaculation. The present results suggest a minimum of 24 hr sexual rest before the PD examination of the gland. This result should be taken into account whenever Doppler sonography is used to evaluate potential hyperaemia in dogs suspected of having prostate abnormalities. © 2017 Blackwell Verlag GmbH.

  1. Fetal Doppler velocimetry and bronchopulmonary dysplasia risk among growth-restricted preterm infants: an observational study.

    Science.gov (United States)

    Lio, Alessandra; Rosati, Paolo; Pastorino, Roberta; Cota, Francesco; Tana, Milena; Tirone, Chiara; Aurilia, Claudia; Ricci, Cinzia; Gambacorta, Alessandro; Paladini, Angela; Mappa, Ilenia; Buongiorno, Silvia; Zannoni, Gian Franco; Romagnoli, Costantino; Vento, Giovanni

    2017-07-20

    To investigate whether fetal growth restriction (FGR) diagnosis, based on pathological prenatal fetal Doppler velocimetry, is associated with bronchopulmonary dysplasia (BPD) independently of being small for gestational age (SGA) per se at birth among very preterm infants. Prospective, observational study. FGR was defined as failing fetal growth in utero and fetal Doppler velocimetry abnormalities. Policlinico Universitario Agostino Gemelli, Roma, Italy. Preterm newborns with gestational age ≤30 weeks and birth weight (BW) ≤1250 g. Bronchopulmonary dysplasia. In the study period, 178 newborns were eligible for the study. Thirty-nine infants (22%) were considered fetal growth-restricted infants. Among the 154 survived babies at 36 weeks postmenstrual age, 12 out of 36 (33%) of the FGR group developed BPD versus 8 out of 118 (7%) of the NO-FGR group (p<0.001). BPD rate was sixfold higher among the SGA-FGR infants compared with the SGA-NO-FGR infants. In a multivariable model, FGR was significantly associated with BPD risk (OR 5.1, CI 1.4 to 18.8, p=0.01), independently from BW z-score that still remains a strong risk factor (OR 0.5, CI 0.3 to 0.9, p=0.01). Among SGA preterm infants, BPD risk dramatically increases when placenta dysfunction is the surrounding cause of low BW. Antenatal fetal Doppler surveillance could be a useful tool for studying placenta wellness and predicting BPD risk among preterm babies. Further research is needed to better understand how FGR affects lung development. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  2. Role of colour doppler sonography in adnexal masses

    Directory of Open Access Journals (Sweden)

    Shazia Ashraf Khan, Aamina Banoo

    2014-04-01

    Full Text Available Objective: To evaluate the role of colour Doppler sonography in differentiating between benign and malignant adnexal masses. Materials & Methods: One hundred women diagnosed with adnexal masses underwent colour Doppler sonography. Resistance index (RI and Pulsatility index (PI were calculated in each case and lowest RI and PI obtained at any point in the mass were considered for analysis. Masses which were completely a vascular were considered as benign. Histopathological diagnosis was obtained in each case. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of colour Doppler were calculated. Results: Mean RI and Mean PI were significantly lower in malignant masses (0.34 & 0.95 respectively as compared to benign masses (0.72 & 1.97 respectively. Out of 81 benign cases, Doppler could correctly diagnose 78 cases as benign, but labelled 3 cases as malignant which were actually benign. Out of 19 malignant cases, 16 cases were correctly diagnosed, whereas 3 cases were missed by Doppler. Our study showed a sensitivity of 84.2%, specificity of 96.3%, positive predictive value of 84.2%, negative predictive value of 96.3% and accuracy of 94% for colour Doppler. Conclusion: Colour Doppler sonography is helpful in differentiating benign from malignant adnexal masses.

  3. Use of Doppler ultrasound for non-invasive urodynamic diagnosis

    Directory of Open Access Journals (Sweden)

    Hideo Ozawa

    2009-01-01

    Full Text Available Objectives: A totally non-invasive transperineal urodynamic technique using Doppler ultrasonography has been developed. Methods: Since normal urine does not have blood cells, urine was thought not to produce the Doppler effects. However, basic studies confirmed that the decrease of pressure at high velocity (Bernouilli effect caused dissolved gas to form microbubbles, which are detected by Doppler ultrasonography. Subjects sat and the probe was advanced via remote control to achieve gentle contact with the perineal skin. The digital uroflow data signals and the color Doppler ultrasound video images were processed on a personal computer. The flow-velocity curves from two sites; the distal prostatic urethra just above the external sphincter (V1 and the sphincteric urethra (V2 were plotted against time. The parameters of both the pressure-flow studies and the Doppler ultrasound urodynamic studies were compared in men who had various degrees of obstruction. Results: Functional cross-sectional area at prostatic urethra (A1, calculated by Q max /V1, was lower in the group of bladder outlet obstruction (BOO vs. control group. Velocity ratio (VR, which was calculated by V1/V2, was the parameter having the best correlation with BOO index, though A1 had a similar correlation. This method is viable to diagnose the degree of BOO. Conclusions: The development of non-invasive Doppler ultrasound videourodynamics (Doppler UDS will dramatically expand the information on voiding function.

  4. ROLE OF DOPPLER STUDY IN THE EVALUATION OF INTRAUTERINE GROWTH RETARDATION

    Directory of Open Access Journals (Sweden)

    Prasad

    2015-10-01

    Full Text Available BACKGROUND AND OBJECTIVE : Intrauterine growth retardation (IUGR is a fetal growth disorder defined on the basis of a fetal weight below 10 th percentile for the corresponding gestational age. Our study was an effort at establishing the role of Umbilical artery (UA and Middle cere bral artery (MCA Doppler indices in predicting the adverse perinatal out come in clinically suspected IUGR pregnancies, and to determine the role of Doppler velocimetry in clinical management of such pregnancies. Elevation of the umbilical artery systolic /diastolic ratio or of the pulsatility index (PI; absent or reversed end - diastolic flow in the umbilical artery and decreased systolic/diastolic ratio or pulsatility index in the fetal internal carotid and middle cerebral arteries are the predictors of ab normal perinatal outcome. Our study was to evaluate the role of ratio of pulsatility index (PI which is called as Cerebroplacental Ratio i.e. MCAPI/UAPI Doppler ratio as the most accurate predictor of adverse perinatal outcome among women with clinical sus picion of IUGR attending our (SVRR Govt. hospital. METHODOLOGY : 50 Antenatal women attending the antenatal O.P.D who were clinically suspected as having growth retardation based on clinical history of previous child with growth retardation , signs of pallor ( anaemia and high documented Blood pressures – s/o PIH, reduced abdominal height for gestational age , were evaluated using screening ultrasound. Doppler velocity wave forms were obtained from umbilical artery and fetal middle cerebral artery fro m all the 50 cases. 16 cases were followed up with repeat Doppler. Pulsatility index ratio of middle cerebral artery and umbilical artery, also called as Cerebroplacental ratio was evaluated in each case. Abnormal ratio is defined as Cerebroplacental ratio < 1.08 was considered as a cut off value. Ratio was calculated and correlated clinically with the perinatal outcomes – in the form of IUD’s, low APGAR

  5. Evaluation of flow velocity in unilateral middle cerebral artery stenosis by Transcranial Doppler.

    Science.gov (United States)

    Wang, Lin; Xing, Yingqi; Li, Yang; Han, Ke; Chen, Jiafeng

    2014-11-01

    To determine the optimal velocity values in diagnosing unilateral middle cerebral artery (MCA) stenosis by Transcranial Doppler (TCD), and improve the diagnostic accuracy using magnetic resonance angiography (MRA), a total of 302 unilateral MCA stenosis patients undergoing TCD also consented to a MRA of the intracranial arteries. The peak systolic velocity (PSV) and each MCA spectrum for each patient were recorded. Using the MRA to confirm, the degree of middle cerebral artery stenosis was categorized into four groups: normal (normal caliber and signal), mild (PSV values for normal and stenosis were 160 cm/s. For mild and moderate were 200 cm/s, for moderate and severe were 280 cm/s. Using PSV as the diagnostic criteria, the Kappa number was >0.668. The optimal PSV differential value for mild and moderate was 70 cm/s, for moderate and severe at 120 cm/s. Optimal combined criteria for moderate stenosis were PSV >200 cm/s and PSV differential value >70 cm/s (specificity 87.2 %), for severe stenosis were PSV >280 cm/s and PSV differential value >120 cm/s (sensibility 81.6 %). Transcranial Doppler distinguishes normal and MCA stenosis with a reduced lumen diameter of less than 50 %. Using the PSV criteria, TCD has a high coincidence rate with MRA in the diagnosis of MCA stenosis. Combined PSV differential value and the abnormal spectrum may improve the accuracy of TCD in diagnosing moderate or severe stenosis.

  6. Myocardial tissue Doppler velocities in fetuses with hypoplastic left heart syndrome

    Directory of Open Access Journals (Sweden)

    Himesh V Vyas

    2011-01-01

    Full Text Available Background : Tissue Doppler Imaging (TDI is a sensitive index of myocardial function. Its role in the fetus has not been extensively evaluated. Objective: To compare myocardial tissue Doppler velocities in fetuses with hypoplastic left heart syndrome (HLHS to those of normal fetuses (matched for gestational age. Methods: Cross-sectional retrospective study conducted at 2 large perinatal centers (2003-2007. Fetuses with HLHS ( n = 13 were compared with normal fetuses ( n = 207 in 5 gestational age groups. TDI data included peak systolic (s′, peak early (e′, and late diastolic velocities (a′. Linear regression was used to compare TDI parameters in fetuses with HLHS to normal fetuses matched for gestational age. Results: Fetuses with HLHS had significantly reduced lateral tricuspid annular e′ as compared to normal fetuses. Both normal fetuses and those with HLHS had linear increase in TDI velocities with advancing gestational age. Conclusions: TDI velocities are abnormal in fetuses with HLHS. TDI can be useful in serial follow-up of cardiac function in fetuses with HLHS.

  7. Evaluation of oscillometric and Doppler ultrasonic methods of indirect blood pressure estimation in conscious dogs

    Science.gov (United States)

    Haberman, Christopher E.; Kang, Chang W.; Morgan, Jefferson D.

    2006-01-01

    Abstract To assess the accuracy and precision of indirect measurements of systemic arterial blood pressure (BP), results obtained with an oscillometric device (BPo) and a Doppler ultrasonic device (BPud) were compared with those obtained by direct radiotelemetry (BPrt) in 12 conscious beagles. The correlation between indirectly obtained and directly measured values for BP parameters ranged widely for the different indirect methods and sites of cuff placement, with R2 between 0.001 and 0.901. Both indirect methods underestimated all BP parameters, the degree of underestimation increasing at higher values for the BP. The highest correlation occurred when estimates were the average of 5 values consecutively obtained with the oscillometric device and cuff placement at the coccygeal artery (R2 = 0.854 for mean BPo, 0.886 for systolic BPo, and 0.901 for diastolic BPo; P < 0.0001 for all parameters) or with the ultrasonic Doppler device at the metatarsal arteries (R2 = 0.810 for systolic BPud; P < 0.0001). Multiple consecutively obtained values are advised, as this approach improves the reliability of indirect BP measurements. The strong correlation between directly measured values and estimates derived as the average of 5 consecutive indirectly obtained values indicates that the latter approach provides a useful estimate of BP in conscious dogs and is likely to be useful in monitoring disease progress and treatment in dogs with abnormal BP. PMID:16850944

  8. [Ultrasound and color Doppler applications in nephrology. The normal kidney: anatomy, vessels and congenital anomalies].

    Science.gov (United States)

    Meola, Mario; Petrucci, Ilaria; Giovannini, Lisa; Samoni, Sara; Dellafiore, Carolina

    2012-01-01

    Gray-scale ultrasound is the diagnostic technique of choice in patients with suspected or known renal disease. Knowledge of the normal and abnormal sonographic morphology of the kidney and urinary tract is essential for a successful diagnosis. Conventional sonography must always be complemented by Doppler sampling of the principal arterial and venous vessels. B-mode scanning is performed with the patient in supine, prone or side position. The kidney can be imaged by the anterior, lateral or posterior approach using coronal, transverse and oblique scanning planes. Morphological parameters that must be evaluated are the coronal diameter, the parenchymal thickness and echogenicity, the structure and state of the urinary tract, and the presence of congenital anomalies that may mimic a pseudomass. The main renal artery and the hilar-intraparenchymal branches of the arterial and venous vessels should be accurately evaluated using color Doppler. Measurement of intraparenchymal resistance indices (IP, IR) provides an indirect and quantitative parameter of the stiffness and eutrophic or dystrophic remodeling of the intrarenal microvasculature. These parameters differ depending on age, diabetic and hypertensive disease, chronic renal glomerular disease, and interstitial, vascular and obstructive nephropathy.

  9. Quantitative analysis of normal fetal brain volume and flow by three-dimensional power Doppler ultrasound.

    Science.gov (United States)

    Hsu, Ju-Chun; Wu, Yi-Cheng; Wang, Peng-Hui; Wang, Hsing-I; Juang, Chi-Mou; Chen, Yi-Jen; Chang, Chia-Ming; Horng, Huann-Cheng; Chen, Chih-Yao; Yang, Ming-Jie; Yen, Ming-Shyen; Chao, Kuan-Chong

    2013-09-01

    Assessment of the fetal brain volume and blood flow is important in the evaluation of fetal growth. We used three-dimensional (3D) ultrasound and power Doppler to assess the fetal brain volume and the blood flow index during normal gestation. The relationships of these parameters were further analyzed. We assessed the total volume and the blood flow index of the fetal brain in normal pregnancies using 3D ultrasound (Voluson 730). The bilateral parietal diameter (BPD) plane was measured by a 3D transabdominal probe to scan the fetal brain under the power Doppler mode. Then, we quantitatively assessed the total volume of the fetal brain, mean grey area (MG), vascularization index (VI), flow index (FI), and vascularization-flow index (VFI) by applying Kretz VOCAL software. The study included 126 fetuses, ranging from 15 to 38 weeks of gestation. The total volume of the fetal brain was highly positively correlated with the gestational age (GA) (correlation coefficient [r] = 0.976, p flow development quantitatively. Our study indicates that the fetal brain vascularization and blood flow correlates significantly with the advancement of GA. This information may serve as a reference point for further studies of the fetal brain volume and blood flow in abnormal conditions. Copyright © 2013. Published by Elsevier B.V.

  10. Interferometric millimeter wave and THz wave doppler radar

    Science.gov (United States)

    Liao, Shaolin; Gopalsami, Nachappa; Bakhtiari, Sasan; Raptis, Apostolos C.; Elmer, Thomas

    2015-08-11

    A mixerless high frequency interferometric Doppler radar system and methods has been invented, numerically validated and experimentally tested. A continuous wave source, phase modulator (e.g., a continuously oscillating reference mirror) and intensity detector are utilized. The intensity detector measures the intensity of the combined reflected Doppler signal and the modulated reference beam. Rigorous mathematics formulas have been developed to extract bot amplitude and phase from the measured intensity signal. Software in Matlab has been developed and used to extract such amplitude and phase information from the experimental data. Both amplitude and phase are calculated and the Doppler frequency signature of the object is determined.

  11. A Rayleigh Doppler Frequency Estimator Derived from Maximum Likelihood Theory

    DEFF Research Database (Denmark)

    Hansen, Henrik; Affes, Sofiene; Mermelstein, Paul

    1999-01-01

    Reliable estimates of Rayleigh Doppler frequency are useful for the optimization of adaptive multiple access wireless receivers.The adaptation parameters of such receivers are sensitive to the amount of Doppler and automatic reconfiguration to the speed of terminalmovement can optimize cell...... capacities in low and high speed situations.We derive a Doppler frequency estimatorusing the maximum likelihood method and Jakes model [\\ref{Jakes}] of a Rayleigh fading channel. This estimator requires an FFT and simple post-processing only. Its performance is verifiedthrough simulations and found to yield...

  12. Mapping global winds with satellite borne Doppler lidar - A plan

    Science.gov (United States)

    Fitzjarrald, D.

    1987-01-01

    The application of the Laser Atmospheric Wind Sounder to the EOS and Space Station is proposed. The use of pulsed, CO2 Doppler lidar to measure wind is described. The design requirements for a Doppler lidar operating in space, and the need to study the global distribution of naturally occurring atmospheric aerosols are discussed. The space-based Doppler lidar wind data will be useful for improving the skill of numerical weather predictions, for studying large-scale atmospheric circulation and climate dynamics, and for analyzing global biogeochemical and hydrological cycles.

  13. Processor operated correlator with applications to laser Doppler signals

    DEFF Research Database (Denmark)

    Bisgaard, C.; Johnsen, B.; Hassager, Ole

    1984-01-01

    A 64-channel correlator is designed with application to the processing of laser Doppler anemometry signals in the range 200 Hz to 250 kHz. The correlator is processor operated to enable the consecutive sampling of 448 correlation functions at a rate up to 500 Hz. Software is described to identify...... a Doppler frequency from each correlation and the system is especially designed for transient flow signals. Doppler frequencies are determined with an accuracy of about 0.1%. Review of Scientific Instruments is copyrighted by The American Institute of Physics....

  14. Sub-Doppler laser cooling of potassium atoms

    Energy Technology Data Exchange (ETDEWEB)

    Landini, M. [LENS and Dipartimento di Fisica e Astronomia, Universita di Firenze, I-50019 Sesto Fiorentino (Italy); INFN, Sezione di Firenze, I-50019 Sesto Fiorentino (Italy); Dipartimento di fisica, Universita di Trento, I-38123 Povo (Trento) (Italy); Roy, S.; Carcagni, L.; Trypogeorgos, D. [LENS and Dipartimento di Fisica e Astronomia, Universita di Firenze, I-50019 Sesto Fiorentino (Italy); Fattori, M.; Inguscio, M.; Modugno, G. [LENS and Dipartimento di Fisica e Astronomia, Universita di Firenze, I-50019 Sesto Fiorentino (Italy); INFN, Sezione di Firenze, I-50019 Sesto Fiorentino (Italy)

    2011-10-15

    We investigate the sub-Doppler laser cooling of bosonic potassium isotopes, whose small hyperfine splitting has so far prevented cooling below the Doppler temperature. We find instead that the combination of a dark optical molasses scheme that naturally arises in this kind of system and an adiabatic ramping of the laser parameters allows us to reach sub-Doppler temperatures for small laser detunings. We demonstrate temperatures as low as 25{+-}3 {mu}K and 47{+-}5 {mu}K in high-density samples of the two isotopes {sup 39}K and {sup 41}K, respectively. Our findings should find application to other atomic systems.

  15. Ghanaian Women Enter into Popular Entertainment | Collins ...

    African Journals Online (AJOL)

    This article discuses the problems faced by West African and particularly Ghanaian female popular performers and the various factors that have, since the 1960's led to increasing numbers of women entering the professional theatre and the commercial entertainment industry. The study examines the upsurge of female ...

  16. Entering a Crack: An Encounter with Gossip

    Science.gov (United States)

    Henderson, Linda

    2014-01-01

    In this paper, I enter a crack to think otherwise about the concept "gossip". Drawing on previous scholarship engaging with Deleuzian concepts to inform research methodologies, this paper builds on this body of work. Following Deleuze and Guattari, the paper undertakes a mapping of gossip, subsequent to an encounter with a crack.…

  17. Experimental Yersinia pseudotuberculosis enteritis in laboratory ...

    African Journals Online (AJOL)

    and guinea pigs. Animals orally fed with clean water showed no symptoms of yersiniosis. Rabbits infected with Y. pseudotuberculosis showed signs of illness while guinea pigs did not show any clinical sign. Visceral organs of infected rabbits showed enteritis with necrotic lesions but no pathological changes were observed ...

  18. Campylobacter enteritis among children in Dembia District ...

    African Journals Online (AJOL)

    Objective: To estimate the magnitude of Campylobacter enteritis in children below fifteen years of age. Design: A cross-sectional survey. Setting: Seven villages found in the outskirts of Kolla Diba town were covered. The town is located 35 kilometres away from Gondar teaching hospital. Participants: Stool specimens were ...

  19. Astronaut John Glenn Enters Friendship 7

    Science.gov (United States)

    1962-01-01

    Astronaut John Glenn enters the Mercury spacecraft, Friendship 7, prior to the launch of MA-6 on February 20, 1961 and became the first American who orbited the Earth. The MA-6 mission was the first manned orbital flight boosted by the Mercury-Atlas vehicle, a modified Atlas ICBM (Intercontinental Ballistic Missile), lasted for five hours, and orbited the Earth three times.

  20. CAMPYLOBACTER ENTERITIS AMONG CHILDREN IN DEMBIA ...

    African Journals Online (AJOL)

    hi-tech

    2000-12-12

    Dec 12, 2000 ... ABSTRACT. Objective: To estimate the magnitude of Campylobacter enteritis in children below fifteen years of age. Design: A cross-sectional survey. Setting: Seven ... Campylobacter species can cause infection in all age groups but the ..... stereotype distribution of Campylobacter jejuni and C. coli isolated.

  1. [Enteral alimentation at home: why PEG now?].

    Science.gov (United States)

    Suzuki, Y; Hanyu, N; Kashiwagi, H; Kubo, T; Aoki, T

    1996-12-01

    The history of percutaneous endoscopic gastrostomy (PEG) is relatively short. In 1980, a report entitled "Gastrostomy without laparotomy: A percutaneous endoscopic technique" by Ponsky and Gaudere was first published in the Journal of Pediatric Surgery. Thereafter, PEG soon saw widespread use in Western countries because of its clinical efficacy and economy. It has been performed in about 170,000 cases annually in the US. In contrast, its spread in Japan has been extremely slow: only about 10,000 cases have undergone this procedure annually, and this number accounted for less than 5% of patients receiving enteral alimentation. The reason why PEG has not spread may be the medical insurance system in Japan and the local distaste for operation scarring. However, in consideration of the unprecedented ageing of society that is surely coming in the near future, the role of PEG in Japan must be reexamined. In this report, we presented the methodology of enteral alimentation at home by means of PEG, giving special consideration to: (1) "What points are improved by using enteral alimentation at home by means of PEG in various diseases; (2) dysphagia due to cerebral angiopathy; (3) terminal cancer; (4) otolaryngological diseases; and (5) Crohn disease. We also discussed "Why PEG is important now?" in performing enteral alimentation at home.

  2. Kokainudløst iskaemisk enteritis

    DEFF Research Database (Denmark)

    Hobolth, Lise; Bendtsen, Flemming

    2009-01-01

    and a pill cam capsule endoscopy were normal. In all cases the condition normalized spontaneously. A thorough interview revealed a recreational use of cocaine, and diary recordings confirmed the association between her abdominal pain and cocaine use. Ischaemic enteritis has previously been described...... in cocaine users. Udgivelsesdato: 2009-Sep...

  3. Aspects of enteral nutrition in cancer chemotherapy

    NARCIS (Netherlands)

    Smit, Jitske Martha

    1985-01-01

    This thesis deals with several aspects of the influences of intensive cancer chemotherapy on the nutritional status, the metabolism, and the gastrointestinal tract of the host and describes whether these results can be influenced by enteral hyperalimentation, We studied these aspects in patients

  4. A transcranial doppler study in interictal migraine and tension-type headache.

    Science.gov (United States)

    Arjona, Antonio; de Torres, Luis A Perula; Serrano-Castro, Pedro J; Guardado-Santervas, Pedro L; Olivares, Jesus; Rubí-Callejon, Jose

    2007-09-01

    To use transcranial Doppler (TCD) sonography to determine if patients with migraine without aura have interictal hemodynamic abnormalities compared with patients who have episodic tension-type headache (TH). Thirty-six migraine patients without aura and 51 TH patients (age range, 16-50 years) who were diagnosed according to the criteria of the International Headache Society 1988 participated in the study. Forty-four healthy volunteers, matched for age and sex, formed the control group. Time-averaged mean velocity (TAMV), pulsatility index (PI), and breath-holding index (BHI) were measured via TCD sonography in the middle cerebral artery. TAMV was higher in migraine without aura than in episodic TH (p = 0.034). There were no differences between groups regarding PI or BHI. Our findings support the arteriolar vasodilatation theory in migraine without aura. (c) 2007 Wiley Periodicals, Inc.

  5. Doppler ultrasound evaluation of pattern of venous incompetance and relation with skin changes in varicose vein patients

    Directory of Open Access Journals (Sweden)

    HP Pant

    2015-06-01

    Full Text Available BACKGROUND Varicosity of lower limb is a common problem in agricultural country like Nepal. Doppler ultrasound is a standard investigation modality for confirmation of diagnosis, evaluation of severity and venous mapping to plan treatment. We aim to find out the epidemiology, common pattern of incompetance, severity assessment by doppler and association of the important doppler variables with skin changes. METHODOLOGY Doppler venous study was done in 56 patients from june 2013 to july 2014. Patients with deep vein thrombosis and peripheral arterial disease were excluded. Altogether 56 patients, 96 limbs were studied. Data was entered in preformed proforma. Doppler study was conducted by senior radiologist with linear probes. Data was entered in SPSS software version 16 and statistical significance was calculated using chi square test. RESULTS Bilateral limb involvement was seen in 40 patients and unilateral in 16 patuents only. Skin related changes were seen in 58 limbs. Saphenofemoral junction incompetance was seen in 79(82.2% limbs and was most common pattern of incompetance. Overall, superficial veins were involved in 88(91.7% limbs and deep in 30(31.2% limbs. Prolonged duration of varicosity (>9 year (p=0.000, bilateral limb involvement(p=0.024, reflux in deep venous system(p=0.002, larger Greater Saphenous Vein (GSV size(p=0.003, prolonged duration of reflux(p=0.000 and perforator incompetence (p=0.002 were associated with skin changes. GSV diameter more than 7 mm was associated with reflux significantly (P=0.002. CONCLUSION Superficial vein incompetance is common pattern compared to deep venous system. Sapheno Femoral Junction (SFJ incompetance is the commonest pattern. Larger caliber of vein, prolonged duration of reflux, reflux in deep venous system and perforator insufficiency are significantly associated with skin changes.DOI: http://dx.doi.org/10.3126/jcmsn.v10i3.12770 Journal of College of Medical Sciences-Nepal, 2014, Vol-10, No-3

  6. Doppler spectral characteristics of infrainguinal vein bypasses

    DEFF Research Database (Denmark)

    Nielsen, Tina G; von Jessen, F; Sillesen, H

    1993-01-01

    of arteriovenous fistulas the initially antegrade diastolic velocity was replaced by a retrograde flow within 3 months, whereas a forward flow in diastole was sustained in grafts with patent fistulas. Abnormal Duplex findings in 31 patients led to angiography and revision in 13 cases. Four revised grafts failed......, while nine remained patent at follow-up 1-12 months later. Ten (56%) of 18 non-revised bypasses with abnormal Duplex findings failed within 9 months compared to 1 (1%) of 76 bypasses with a normal velocity profile (p ... valuable information concerning haemodynamics of infrainguinal vein bypasses and identifies grafts at risk of thrombosis. Inclusion of low resistance index (detection of stenoses appears to improve the sensitivity of Duplex scanning....

  7. Can Three-dimensional (3D power Doppler and uterine artery Doppler differentiate between fibroids and adenomyomas?

    Directory of Open Access Journals (Sweden)

    Eman Elkattan

    2016-03-01

    Full Text Available Purpose: To determine if the three-dimensional power Doppler and uterine arteries Doppler were able to differentiate between fibroids and adenomyomas. Methods: 123 patients who were scheduled for hysterectomy were enrolled in the study. They were evaluated by ultrasound before hysterectomy. We included only cases with either fibroids or adenomymas. For each benign myometrial mass, mass volume, 3D power Doppler vascularization index (VI, flow index (FI and vascularization flow index (VFI and uterine artery Doppler indices were measured. The results were compared with the histopathological examination. Results: No significant difference was detected between the volume of the fibroids or the adenomyomas (P = 0.896. There was significant difference in the vascular location of the power Doppler flow between fibroids and adenomyomas being more scattered in adenomyoma and more peripheral in fibroids (P < 0.00. In fibroids, higher 3D power Doppler vascular flow (VI = 2.42 ± 2.0, FI = 39.931 ± 5.8 and VFI = 1.29 ± 1.54 than adenomyomas (VI = 1.19 ± 1.04, FI = 28.33 ± 6.88, VFI = 0.89 ± 0.49. That was statistically significant (P = 0.005, 0.00, 0.004 respectively. The uterine artery Doppler indices (RI, PI showed no significant difference between fibroids and adenomyoma (P = 0.349, 0.067. Conclusion: 3D power Doppler can differentiate between fibroids and adenomyomas. The uterine arteries Doppler Can’t differentiate between fibroids and adenomyomas.

  8. Effect of preload and heart rate on the doppler and tissue doppler-derived myocardial performance index.

    Science.gov (United States)

    Ozdemir, Kurtuluş; Balci, Sibel; Duzenli, Mehmet Akif; Can, Ilknur; Yazici, Mehmet; Aygul, Nazif; Altunkeser, Bulent Behlul; Altintepe, Lutfullah; Turk, Suleyman

    2007-07-01

    Doppler-derived myocardial performance index (MPI) has been described as a noninvasive measurement of LV function. Our aim was to investigate the effect of hemodialysis related volume reduction and heart rate changes on the Doppler-derived LV MPI, and Doppler tissue imaging (DTI) derived left and right ventricular MPI. The study group comprised 32 consecutive patients (mean age: 43 +/- 18 yrs) undergoing hemodialysis. Patients underwent echocardiography before and immediately after hemodialysis session. Left and right ventricular MPI derived from conventional pulsed-wave Doppler and DTI was calculated. The difference in MPI, heart rate and body weight was calculated before and after hemodialysis. Doppler-derived LV MPI, and right ventricular MPI obtained by DTI were increased (p = 0.05) but the LV MPI obtained by DTI was unchanged after hemodialysis. There is a significant positive correlation between the Doppler-derived LV MPI difference and volume reduction (r = 0.38, p = 0.032). The heart rate difference was correlated with Doppler-derived LV MPI difference, and DTI derived right ventricular MPI difference (r = 0.38, p = 0.034; r = 0.48, p = 0.006, respectively). Whereas, DTI derived LV MPI difference was not correlated with heart rate difference. By the multivariate analysis, there was no correlation between Doppler-derived LV MPI difference with heart rate difference, and volume reduction. Right ventricular MPI difference correlated with heart rate difference (r = 0.41, p = 0.021) but not with volume reduction. Doppler-derived MPI is partially influenced by preload and heart rate changes. However, DTI derived LV MPI is not influenced by preload and heart rate changes.

  9. Mastoid abnormalities in Down syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Glass, R.B.J.; Yousefzadeh, D.K.; Roizen, N.J.

    1989-06-01

    Hearing loss and otitis media are commonly associated with Down syndrome. Hypoplasia of the mastoids is seen in many affected children and sclerosis of mastoid bones is not uncommon in Down syndrome. Awareness and early recognition of mastoid abnormality may lead to appropriate and timely therapy, thereby preserving the child's hearing or compensating for hearing loss; factors which are important for learning and maximum development.

  10. Normal and abnormal skin color.

    Science.gov (United States)

    Ortonne, J P

    2012-12-01

    The varieties of normal skin color in humans range from people of "no color" (pale white) to "people of color" (light brown, dark brown, and black). Skin color is a blend resulting from the skin chromophores red (oxyhaemoglobin), blue (deoxygenated haemoglobin), yellow-orange (carotene, an exogenous pigment), and brown (melanin). Melanin, however, is the major component of skin color ; it is the presence or absence of melanin in the melanosomes in melanocytes and melanin in keratinocytes that is responsible for epidermal pigmentation, and the presence of melanin in macrophages or melanocytes in the dermis that is responsible for dermal pigmentation. Two groups of pigmentary disorders are commonly distinguished: the disorders of the quantitative and qualitative distribution of normal pigment and the abnormal presence of exogenous or endogenous pigments in the skin. The first group includes hyperpigmentations, which clinically manifest by darkening of the skin color, and leukodermia, which is characterized by lightening of the skin. Hypermelanosis corresponds to an overload of melanin or an abnormal distribution of melanin in the skin. Depending on the color, melanodermia (brown/black) and ceruloderma (blue/grey) are distinguished. Melanodermia correspond to epidermal hypermelanocytosis (an increased number of melanocytes) or epidermal hypermelanosis (an increase in the quantity of melanin in the epidermis with no modification of the number of melanocytes). Ceruloderma corresponds to dermal hypermelanocytosis (abnormal presence in the dermis of cells synthesizing melanins) ; leakage in the dermis of epidermal melanin also exists, a form of dermal hypermelanosis called pigmentary incontinence. Finally, dyschromia can be related to the abnormal presence in the skin of a pigment of exogenous or endogenous origin. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  11. [Normal and abnormal skin color].

    Science.gov (United States)

    Ortonne, J-P

    2012-11-01

    The varieties of normal skin color in humans range from people of "no color" (pale white) to "people of color" (light brown, dark brown, and black). Skin color is a blend resulting from the skin chromophores red (oxyhaemoglobin), blue (deoxygenated haemoglobin), yellow-orange (carotene, an exogenous pigment), and brown (melanin). Melanin, however, is the major component of skin color ; it is the presence or absence of melanin in the melanosomes in melanocytes and melanin in keratinocytes that is responsible for epidermal pigmentation, and the presence of melanin in macrophages or melanocytes in the dermis that is responsible for dermal pigmentation. Two groups of pigmentary disorders are commonly distinguished: the disorders of the quantitative and qualitative distribution of normal pigment and the abnormal presence of exogenous or endogenous pigments in the skin. The first group includes hyperpigmentations, which clinically manifest by darkening of the skin color, and leukodermia, which is characterized by lightening of the skin. Hypermelanosis corresponds to an overload of melanin or an abnormal distribution of melanin in the skin. Depending on the color, melanodermia (brown/black) and ceruloderma (blue/grey) are distinguished. Melanodermia correspond to epidermal hypermelanocytosis (an increased number of melanocytes) or epidermal hypermelanosis (an increase in the quantity of melanin in the epidermis with no modification of the number of melanocytes). Ceruloderma correspond to dermal hypermelanocytosis (abnormal presence in the dermis of cells synthesizing melanins) ; leakage in the dermis of epidermal melanin also exists, a form of dermal hypermelanosis called pigmentary incontinence. Finally, dyschromia can be related to the abnormal presence in the skin of a pigment of exogenous or endogenous origin. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  12. Goldenhar syndrome and urogenital abnormalities

    Directory of Open Access Journals (Sweden)

    Mohan Marulaiah

    2003-01-01

    Full Text Available The Goldenhar syndrome (oculo-auriculo-vertebral syn-drome or 1st and 2nd branchial arch syndrome is a com-plex of craniofacial anomalies. It has been associated with anomalies in other systems and with abnormalities of the urogenital system. We present a case of Goldenhar syn-drome with multiple renal anomalies and a urogenital si-nus, which has not been reported before.

  13. Identification of patients at risk for preeclampsia with the use of uterine artery Doppler velocimetry and copeptin.

    Science.gov (United States)

    Yeşil, Ali; Kanawati, Ammar; Helvacıoğlu, Çağlar; Kaya, Cihan; Özgün, Çağseli Göksu; Cengiz, Hüseyin

    2017-11-01

    To investigate the relationship between maternal copeptin levels and uterine artery Doppler examination and progress of preeclampsia. A cross-sectional study was designed with women those were screened at 20 + 0 - 24+  6 weeks' gestation between May 2014 and August 2014. The obstetric records of all normotensive women were examined. Uterine artery Doppler velocimetry results and serum copeptin levels were measured. The patients were divided into two groups according to normal (n = 67) and abnormal uterine artery Doppler (n = 21) findings. Maternal age was significantly lower in group 1 (n = 21, 23.9%) than in group 2 (n= 67, 76.1%) (p copeptin levels between the two groups. Maternal serum copeptin levels were higher in women who subsequently developed preeclampsia. There was also a significant correlation between copeptin levels and the presence of preeclampsia. (p = 0.002). Copeptin levels are significantly higher in patients who develop preeclampsia.

  14. Contribution of spiral artery blood flow changes assessed by transvaginal color Doppler sonography for predicting endometrial pathologies

    Directory of Open Access Journals (Sweden)

    Suna Kabil Kucur

    2013-01-01

    Full Text Available ive: To investigate the diagnostic value of blood flow measurements in spiral artery by transvaginal color Doppler sonography (CDS in predicting endometrial pathologies.Methods: Ninety-seven patients presenting with abnormal uterine bleeding and requiring endometrial assessment were included in this prospective observational study. Endometrial thickness, structure and echogenicity were recorded. Pulsatility index (PI and resistive index (RI of the spiral artery were measured by transvaginal CDS. Endometrial sampling was performed for all subjects. Sonographic and hystopathologic findings were compared.Results: The histopathological diagnoses were as follows; 39 cases (40.2% endometrial polyp, 9 cases (9.3% endometrial hyperplasia, 10 cases (10.3 submucous myoma, 7 cases (7.2% endometrium cancer, and 32 cases (33% nonspecific findings. The spiral artery PI in endometrium cancer group was highly significantly lower than other groups (p<0.01. The spiral artery RI was also significantly lower in the patients with malignant histology (p<0.05. Conclusion: Endometrial pathologies are associated significantly with endometrial spiral artery Doppler changes.Key words: Spiral artery, Doppler ultrasonography, endometrium

  15. Doppler study of cerebral arteries in hypercholesterolemia

    Directory of Open Access Journals (Sweden)

    Ghabili K

    2011-03-01

    Full Text Available Mehdi Farhoudi1, Kaveh Mehrvar2, Naser Aslanabadi3, Kamyar Ghabili1, Nazila Rasi Baghmishe4, Farzad Ilkhchoei41Neuroscience Research Center, 2Razi Hospital, 3Department of Cardiology, 4Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranBackground: Hypercholesterolemia is one of the major modifiable risk factors for atherosclerosis of the coronary and carotid arteries. Although transcranial Doppler (TCD studies of the cerebral arteries are indicative of decreased cerebral blood flow velocities in patients with hypercholesterolemia, the number of these studies has been limited. The aim of this study was to assess the hemodynamic status of the cerebral arteries in patients with hypercholesterolemia using TCD.Methods: In a case-control study, 60 individuals, including 30 hypercholesterolemic cases (low-density lipoprotein [LDL] > 160 mg/dL and 30 healthy controls were enrolled. Other arterial risk factors, including diabetes mellitus, hypertension, smoking, and obesity (body mass index > 30, were evaluated and matched as well. TCD was used to assess the hemodynamics of the intracranial arteries as well as the internal carotid arteries. The mean blood flow velocity, pulsatility index, and resistance index were recorded in all the arteries.Results: The mean blood flow velocity, pulsatility index, and resistance index of the intracranial arteries and internal carotid arteries were not significantly different between the two groups (P > 0.05. However, those with higher levels of LDL (>180 mg/dL showed significantly lower mean blood flow velocity and resistance index of the internal carotid arteries than the healthy controls. In addition, individuals with high-density lipoprotein (HDL <35 mg/dL had significantly lower mean blood flow velocity in the internal carotid arteries.Conclusion: Hypercholesterolemia (LDL > 160 mg/dL does not seem to have a detrimental effect on the hemodynamic status of the intracranial arteries and internal

  16. GRIP DOPPLER AEROSOL WIND LIDAR (DAWN) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The Doppler Aerosol WiNd (DAWN), a pulsed lidar, operated aboard a NASA DC-8 aircraft during the Genesis and Rapid Intensification Processes (GRIP) field campaign....

  17. Laser Doppler technology applied to atmospheric environmental operating problems

    Science.gov (United States)

    Weaver, E. A.; Bilbro, J. W.; Dunkin, J. A.; Jeffreys, H. B.

    1976-01-01

    Carbon dioxide laser Doppler ground wind data were very favorably compared with data from standard anemometers. As a result of these measurements, two breadboard systems were developed for taking research data: a continuous wave velocimeter and a pulsed Doppler system. The scanning continuous wave laser Doppler velocimeter developed for detecting, tracking and measuring aircraft wake vortices was successfully tested at an airport where it located vortices to an accuracy of 3 meters at a range of 150 meters. The airborne pulsed laser Doppler system was developed to detect and measure clear air turbulence (CAT). This system was tested aboard an aircraft, but jet stream CAT was not encountered. However, low altitude turbulence in cumulus clouds near a mountain range was detected by the system and encountered by the aircraft at the predicted time.

  18. Analysis of Doppler Criteria in the Diagnosis Of IUGR

    Directory of Open Access Journals (Sweden)

    Grif Caterina

    2013-06-01

    Full Text Available Introduction: The assessment of the Doppler velocimetric indices of the uterine, umbilical and middle cerebral artery helps in diagnosing and monitoring pregnancies with fetal growth disorder.

  19. Estimation of amputation level with a laser Doppler flowmeter

    DEFF Research Database (Denmark)

    Gebuhr, Peter Henrik; Jørgensen, J P; Vollmer-Larsen, B

    1989-01-01

    Leg amputation levels were decided in 24 patients suffering from atherosclerosis, using the conventional techniques of segmental blood pressure and radioisotope skin clearance. The skin microcirculation was measured and recorded before operation with a laser doppler flowmeter. A high correlation...

  20. The Doppler Effect: A Consideration of Quasar Redshifts.

    Science.gov (United States)

    Gordon, Kurtiss J.

    1980-01-01

    Provides information on the calculation of the redshift to blueshift ratio introduced by the transverse Doppler effect at relativistic speeds. Indicates that this shift should be mentioned in discussions of whether quasars are "local" rather than "cosmological" objects. (GS)

  1. Doppler Ambiguity Resolution Based on Random Sparse Probing Pulses

    Directory of Open Access Journals (Sweden)

    Yunjian Zhang

    2015-01-01

    Full Text Available A novel method for solving Doppler ambiguous problem based on compressed sensing (CS theory is proposed in this paper. A pulse train with the random and sparse transmitting time is transmitted. The received signals after matched filtering can be viewed as randomly sparse sampling from the traditional fixed-pulse repetition frequency (PRF echo signals. The whole target echo could be reconstructed via CS recovery algorithms. Through refining the sensing matrix, which is equivalent to increase the sampling frequency of target characteristic, the Doppler unambiguous range is enlarged. In particular, Complex Approximate Message Passing (CAMP algorithm is developed to estimate the unambiguity Doppler frequency. Cramer-Rao lower bound expressions are derived for the frequency. Numerical simulations validate the effectiveness of the proposed method. Finally, compared with traditional methods, the proposed method only requires transmitting a few sparse probing pulses to achieve a larger Doppler frequency unambiguous range and can also reduce the consumption of the radar time resources.

  2. GPM Ground Validation Doppler on Wheels (DOW) OLYMPEX V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The GPM Ground Validation Doppler on Wheels (DOW) OLYMPEX dataset was obtained by a dual-polarization and dual-frequency X-band mobile radar operated by the Center...

  3. Doppler electron velocimetry : notes on creating a practical tool.

    Energy Technology Data Exchange (ETDEWEB)

    Reu, Phillip L.; Milster, Tom (University of Arizona)

    2008-11-01

    The Doppler electron velocimeter (DEV) has been shown to be theoretically possible. This report attempts to answer the next logical question: Is it a practical instrument? The answer hinges upon whether enough electrons are available to create a time-varying Doppler current to be measured by a detector with enough sensitivity and bandwidth. The answer to both of these questions is a qualified yes. A target Doppler frequency of 1 MHz was set as a minimum rate of interest. At this target a theoretical beam current signal-to-noise ratio of 25-to-1 is shown for existing electron holography equipment. A detector is also demonstrated with a bandwidth of 1-MHz at a current of 10 pA. Additionally, a Linnik-type interferometer that would increase the available beam current is shown that would offer a more flexible arrangement for Doppler electron measurements over the traditional biprism.

  4. CAMEX-4 MIPS 915 MHZ DOPPLER WIND PROFILER V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The University of Alabama in Huntsville (UAH) Mobile Integrated Profiling System (MIPS) is a mobile atmospheric profiling system. It includes a 915 MHz Doppler...

  5. CAMEX-4 MIPS 915 MHZ DOPPLER WIND PROFILER V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The CAMEX-4 MIPS 915 MHZ Doppler Wind Profiler dataset was collected by the University of Alabama in Huntsville (UAH) Mobile Integrated Profiling System (MIPS),...

  6. Extracting and analyzing micro-Doppler from ladar signatures

    Science.gov (United States)

    Tahmoush, Dave

    2015-05-01

    Ladar and other 3D imaging modalities have the capability of creating 3D micro-Doppler to analyze the micro-motions of human subjects. An additional capability to the recognition of micro-motion is the recognition of the moving part, such as the hand or arm. Combined with measured RCS values of the body, ladar imaging can be used to ground-truth the more sensitive radar micro-Doppler measurements and associate the moving part of the subject with the measured Doppler and RCS from the radar system. The 3D ladar signatures can also be used to classify activities and actions on their own, achieving an 86% accuracy using a micro-Doppler based classification strategy.

  7. NAMMA NASA POLARIMETRIC DOPPLER WEATHER RADAR (NPOL) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The NAMMA NASA Polarimetric Doppler Weather Radar (NPOL) dataset used the NPOL, developed by a research team from Wallops Flight Facility, is a fully transportable...

  8. Doppler ultrasound in obstetrics and gynecology. 2. rev. and enl. ed.

    Energy Technology Data Exchange (ETDEWEB)

    Maulik, D. [Winthrop Univ. Hospital, Mineola, NY (United States). Dept. of Obstetrics and Gynecology; Zalud, I. (eds.) [Kapiolani Medical Center for Women and Children, Honolulu, HI (United States)

    2005-07-01

    The second edition of Doppler Ultrasound in Obstetrics and Gynecology has been expanded and comprehensively updated to present the current standards of practice in Doppler ultrasound and the most recent developments in the technology. Doppler Ultrasound in Obstetrics and Gynecology encompasses the full spectrum of clinical applications of Doppler ultrasound for the practicing obstetrician-gynecologist, including the latest advances in 3D and color Doppler and the newest techniques in 4D fetal echocardiography. Written by preeminent experts in the field, the book covers the basic and physical principles of Doppler ultrasound; the use of Doppler for fetal examination, including fetal cerebral circulation; Doppler echocardiography of the fetal heart; and the use of Doppler for postdated pregnancy and in cases of multiple gestation. Chapters on the use of Doppler for gynecologic investigation include ultrasound in ectopic pregnancy, for infertility, for benign disorders and for gynecologic malignancies. (orig.)

  9. Monitoring treatment response with color and power Doppler.

    Science.gov (United States)

    Lagalla, R; Caruso, G; Finazzo, M

    1998-05-01

    Color and power Doppler are now widely used to monitor treatment response because of the latest technologic advances and of the increasing use of echo-enhancing agents. The assessment of treatment response is based on the amount of necrosis obtained and changes in local vascularization indicate a successful treatment. To date, clinical experiences have mainly concerned the treatment of hepatocellular carcinomas, hyperfunctioning nodules of the thyroid and parathyroid glands and the neoadjuvant chemotherapy of breast cancer. Aim of this review is to describe the role and potentials of color and power Doppler in this field. Hepatocellular carcinomas are currently treated with surgery or percutaneous ethanol injection and/or chemoembolization. Treatment response can be monitored with color Doppler: after a successful treatment, color signals are no longer detectable on color Doppler images. Conversely, the presence of arterial signals indicates persistent viable tumor. Unfortunately, color Doppler is limited when the hepatocellular carcinoma is hypovascular, small or deep. Echo-enhancing agents may help overcome these limitations, although spiral computed tomography or dynamic magnetic resonance imaging cannot be replaced yet in the definitive assessment of tumor necrosis. Color and power Doppler are well-established tools in the study of functioning thyroid and parathyroid adenomas after percutaneous ethanol injection. Echo-enhancing agents may improve Doppler sensitivity in the detection of residual viable tissue. Other interesting applications of color and power Doppler in this field are secondary hyperparathyroidism and hyperfunctioning thyreopathies (Graves' disease) treated with mercaptoimidazole. The evaluation of systolic flow velocity in the inferior thyroid artery is more reliable than the quantitative analysis of color signals in monitoring treatment response in Graves' disease. In our experience, systolic velocity in the inferior thyroid artery decreased

  10. Doppler ultrasound findings correlate with tissue vascularity and inflammation in surgical pathology specimens from patients with small intestinal Crohn's disease.

    Science.gov (United States)

    Sasaki, Tomohiko; Kunisaki, Reiko; Kinoshita, Hiroto; Kimura, Hideaki; Kodera, Teruaki; Nozawa, Akinori; Hanzawa, Akiho; Shibata, Naomi; Yonezawa, Hiromi; Miyajima, Eiji; Morita, Satoshi; Fujii, Shoichi; Numata, Kazushi; Tanaka, Katsuaki; Tanaka, Masanori; Maeda, Shin

    2014-06-14

    Crohn's disease (CD) is routinely evaluated using clinical symptoms, laboratory variables, and the CD activity index (CDAI). However, clinical parameters are often nonspecific and do not precisely reflect the actual activity of CD small-intestinal lesions. The purposes of this prospective study were to compare color Doppler ultrasound (US) findings with histological findings from surgically resected specimens and confirm the hypothesis that color Doppler US can distinguish tissue inflammation and fibrosis. Among 1764 consecutive patients who underwent color Doppler US examinations, 10 patients with CD (12 small-intestinal CD lesions) who underwent US examinations before elective small-intestine resection were evaluated in the present study. Areas of thickened intestinal walls were evaluated in terms of blood flow using color Doppler US imaging. The blood flow was semiquantitatively classified as "hyper-flow" and "hypo-flow" according to the Limberg score. Resected lesions were macroscopically and histopathologically processed. Inflammatory cell infiltration, fibrosis and vascularity were evaluated by myeloperoxidase (granulocytes), CD163 (macrophages), CD79a (B cells), CD3 (T cells), Masson's trichrome (fibrosis), and factor VIII staining (vascular walls). All histopathological images were entered into virtual slide equipment and quantified using a quantitative microscopy integrated system (TissueMorph™). There were no significant differences in disease features or laboratory findings between "hypo-flow" lesions (n = 4) and "hyper-flow" lesions (n = 8). Histopathologically, "hyper-flow" lesions showed significantly greater bowel wall vascularity (factor VIII) (p = 0.047) and inflammatory cell infiltration, including CD163 macrophages (p = 0.008), CD3 T cells, and CD79a B cells (p = 0.043), than did "hypo-flow" lesions. There was no apparent association between the blood flow and CDAI. In this study, active CD lesions were macroscopically

  11. Color Doppler Ultrasonography in Mapping Oral Squamous Cell Carcinoma

    Directory of Open Access Journals (Sweden)

    Rahul Gandhi

    2015-07-01

    Full Text Available Background: Although Color Doppler Ultrasonography (CDUS is useful in the diagnosis of various diseases of the head and neck, flow signals in oral malignant masses are less studied; hence the present study assesses the usefulness of Color Doppler Ultrasonography in quantifying oral squamous cell carcinoma (OSCC vascularization. In addition, we determine the hemodynamic parameters by spectral analysis obtained during a Color Doppler Ultrasonography procedure. We have studied the usefulness of Color Doppler Ultrasonography in mapping oral squamous cell carcinoma of the buccal mucosa, tongue and lip. Methods: This case-control study enrolled 60 subjects aged 20-70 years. Group A constituted 30 cases diagnosed with oral squamous cell carcinoma and Group B constituted 30 healthy controls. Ultrasonographic investigation of each mass was performed. The spectral waveform (time-velocity Doppler spectrum of the flow signal was analyzed for the pulsatility index, resistive index, peak systolic velocity (m/sec, and end diastolic velocity (m/sec. All patients had real-time, gray-scale sonography and Color Doppler Ultrasonography with spectral wave analysis. Results: The mean value for the resistive index in patients with oral squamous cell carcinoma was 0.40±0.14 whereas for healthy subjects, it was 0.83±0.07. The mean pulsatility index value in malignant patients was 0.86±0.20 while for healthy subjects, it came-out to be 2.61±0.77. Conclusion: These Doppler indices have been shown to be sensitive and specific for the diagnosis of malignant oral tumors. Although Color Doppler Ultrasonography cannot replace histopathological procedures, it plays a definite role as an adjunct to clinical evaluation of oral squamous cell carcinoma patients.

  12. Diagnosis of cervical cancer with transvaginal color Doppler sonography

    OpenAIRE

    Li-bo DENG; Wei ZHOU; Chang, Shu-Fang; Lin, Ming-Jie

    2011-01-01

    Objective To investigate the imaging features of cervical cancer by transvaginal color Doppler sonography(TVCS),and evaluate the diagnostic value of TVCS.Methods A hundred and thirty cases of cervical intraepithelial neoplasia(CIN) grade Ⅰ-Ⅱ and cervical cancer,diagnosed by Thinprep cytologic test(TCT),cervical biopsy and pathological examination,received TVCS examination.The image characters and color Doppler flow imaging(CDFI) were collected and analyzed.Another 41 cases with normal cervice...

  13. Using doppler radar images to estimate aircraft navigational heading error

    Science.gov (United States)

    Doerry, Armin W [Albuquerque, NM; Jordan, Jay D [Albuquerque, NM; Kim, Theodore J [Albuquerque, NM

    2012-07-03

    A yaw angle error of a motion measurement system carried on an aircraft for navigation is estimated from Doppler radar images captured using the aircraft. At least two radar pulses aimed at respectively different physical locations in a targeted area are transmitted from a radar antenna carried on the aircraft. At least two Doppler radar images that respectively correspond to the at least two transmitted radar pulses are produced. These images are used to produce an estimate of the yaw angle error.

  14. Is Doppler ultrasound useful for evaluating gestational trophoblastic disease?

    OpenAIRE

    Lin,Lawrence H.; Bernardes, Lisandra S; Hase, Eliane A; Koji Fushida; Francisco, Rossana P. V.

    2015-01-01

    Doppler ultrasound is a non-invasive method for evaluating vascularization and is widely used in clinical practice. Gestational trophoblastic neoplasia includes a group of highly vascularized malignancies derived from placental cells. This review summarizes data found in the literature regarding the applications of Doppler ultrasound in managing patients with gestational trophoblastic neoplasia. The PubMed/Medline, Web of Science, Cochrane and LILACS databases were searched for articles publi...

  15. ADAPTIVE NOISE CANCELLATION OF DOPPLER SHIFTED SIGNALS: A LINEAR FRAMEWORK

    OpenAIRE

    Stewart, R. W.; Weiss, S.

    1996-01-01

    In this paper we investigate the performance of single channel adaptive noise cancellation techniques for situations where the noise signal received by the two microphones cannot be related by a fixed weight canceller's (linear) digital filter due to Doppler shift on the two signals. A mathematical signal model is produced, which shows that the adaptive filter is in fact required to identify a time-varying system which incorporates Doppler shift, and potential rapid variations in signal power...

  16. Doppler Tomography of A0620-00

    Science.gov (United States)

    Neilsen, Joseph; Steeghs, D.; Vrtilek, S. D.

    2007-05-01

    We present the results of spectroscopic observations of the quiescent black hole binary A0620-00 with LDSS3 on the Clay telescope at Las Campanas Observatory. We measure absorption-line radial velocities of the secondary and find K2=434.6±0.5 km/s; this is the most precise absorption-line radial velocity measurement for the system to date. By fitting the rotational broadening of the secondary, we measure the mass ratio q=0.060±0.04 these results, combined with the orbital period, imply a minimum mass for the compact object of 3.09±0.04 M⊙. Although X-ray quiescence implies little accretion activity, we find that the disk contributes ≥50% of the light in B and V, and is subject to significant flickering. The variability of the disk makes ellipsoidal constraints on the inclination nearly impossible. Doppler maps in Hα and Hβ show strong disk emission and a bright spot displaced from the gas stream; lower S/N lines show significant bright spot emission, consistent with Marsh et al. (1994). With high S/N, we pursue modulation tomography of Hα and find that the bright spot is strongly modulated at the orbital period. This research was funded by NSF grant 16640156, the Harvard University Graduate School of Arts and Sciences, and a Smithsonian Astrophysical Observatory Clay Fellowship.

  17. Doppler time-of-flight imaging

    KAUST Repository

    Heide, Felix

    2015-07-30

    Over the last few years, depth cameras have become increasingly popular for a range of applications, including human-computer interaction and gaming, augmented reality, machine vision, and medical imaging. Many of the commercially-available devices use the time-of-flight principle, where active illumination is temporally coded and analyzed on the camera to estimate a per-pixel depth map of the scene. In this paper, we propose a fundamentally new imaging modality for all time-of-flight (ToF) cameras: per-pixel velocity measurement. The proposed technique exploits the Doppler effect of objects in motion, which shifts the temporal frequency of the illumination before it reaches the camera. Using carefully coded illumination and modulation frequencies of the ToF camera, object velocities directly map to measured pixel intensities. We show that a slight modification of our imaging system allows for color, depth, and velocity information to be captured simultaneously. Combining the optical flow computed on the RGB frames with the measured metric axial velocity allows us to further estimate the full 3D metric velocity field of the scene. We believe that the proposed technique has applications in many computer graphics and vision problems, for example motion tracking, segmentation, recognition, and motion deblurring.

  18. Zeeman Doppler Maps: Always Unique, Never Spurious?

    Science.gov (United States)

    Stift, Martin J.; Leone, Francesco

    2017-01-01

    Numerical models of atomic diffusion in magnetic atmospheres of ApBp stars predict abundance structures that differ from the empirical maps derived with (Zeeman) Doppler mapping (ZDM). An in-depth analysis of this apparent disagreement investigates the detectability by means of ZDM of a variety of abundance structures, including (warped) rings predicted by theory, but also complex spot-like structures. Even when spectra of high signal-to-noise ratio are available, it can prove difficult or altogether impossible to correctly recover shapes, positions, and abundances of a mere handful of spots, notwithstanding the use of all four Stokes parameters and an exactly known field geometry; the recovery of (warped) rings can be equally challenging. Inversions of complex abundance maps that are based on just one or two spectral lines usually permit multiple solutions. It turns out that it can by no means be guaranteed that any of the regularization functions in general use for ZDM (maximum entropy or Tikhonov) will lead to a true abundance map instead of some spurious one. Attention is drawn to the need for a study that would elucidate the relation between the stratified, field-dependent abundance structures predicted by diffusion theory on the one hand, and empirical maps obtained by means of “canonical” ZDM, I.e., with mean atmospheres and unstratified abundances, on the other hand. Finally, we point out difficulties arising from the three-dimensional nature of the atomic diffusion process in magnetic ApBp star atmospheres.

  19. Signature stability in laser Doppler vibrometry

    Science.gov (United States)

    Iverson, Thomas Z.; Watson, Edward A.

    2017-05-01

    Speckle can complicate signal acquisition in coherent laser systems such as Laser Doppler Vibrometry (LDV). Variations in the speckle pattern at the reliever due to fluctuations in the system such as beam pointing can lead to impulsive events in the signature. The beam size at the object has a direct influence on the size of the speckle at the receiving aperture. Increasing the beam spot size reduces the average speckle size, but also decreases the strength of the signal coupled with the local oscillator in the LDV. In this paper, we derive the relationship between scattering spot size at the object and average speckle size at the receiver. Theory is presented on how increasing the beam diameter at the object can reduce the fluctuations of the heterodyned signal coupled with the Local Oscillator (LO). The Antenna theorem is presented to show the tradeoff between angular field of view and capture area. We show experimental results on the effects of speckle size and decreasing signal strength have on the stability of an LDV signature. We use a kurtosis metric previously reported in the literature to assess the stability and quality of the return signature.

  20. Muscle activity characterization by laser Doppler Myography

    Science.gov (United States)

    Scalise, Lorenzo; Casaccia, Sara; Marchionni, Paolo; Ercoli, Ilaria; Primo Tomasini, Enrico

    2013-09-01

    Electromiography (EMG) is the gold-standard technique used for the evaluation of muscle activity. This technique is used in biomechanics, sport medicine, neurology and rehabilitation therapy and it provides the electrical activity produced by skeletal muscles. Among the parameters measured with EMG, two very important quantities are: signal amplitude and duration of muscle contraction, muscle fatigue and maximum muscle power. Recently, a new measurement procedure, named Laser Doppler Myography (LDMi), for the non contact assessment of muscle activity has been proposed to measure the vibro-mechanical behaviour of the muscle. The aim of this study is to present the LDMi technique and to evaluate its capacity to measure some characteristic features proper of the muscle. In this paper LDMi is compared with standard superficial EMG (sEMG) requiring the application of sensors on the skin of each patient. sEMG and LDMi signals have been simultaneously acquired and processed to test correlations. Three parameters has been analyzed to compare these techniques: Muscle activation timing, signal amplitude and muscle fatigue. LDMi appears to be a reliable and promising measurement technique allowing the measurements without contact with the patient skin.

  1. New laser amplifier improves laser Doppler interferometry

    Science.gov (United States)

    1986-02-01

    The design of a laser light amplifier developed to improve the ability of a laser Doppler interferometry system to measure the high velocities of explosion-driven objects or targets is described. The amplifier increases the laser light intensity and S/N ratio. A green coumarin dye is utilized as if the lasing medium for an argon-ion laser and a blue dye as the frequency shifter to improve coupling between the light-pump power source and lasing medium. The arrangement of amplifier components and the frequency characteristics of the flash lamps and dyes are examined. The design requirements for eliminating chirping and achieving acoustic isolation are discussed. The control of the thermal gradients which produce lens effect is analyzed. The selection of a proper dye concentration for uniform excitation across the active volume of the amplifier is studied; an excitation absorption length of three diameters of active cross section is utilized. In order to increase the amount of pumping light reaching the laser dye and to reduce the number of unwanted wavelengths a optical frequency shifter is employed. The amplifier produces enough light to observe two or more spots on the target, record data for up to 12 microsec, and have an accuracy of 0.5 pct.

  2. Intrahepatic portosystemic venous shunts: diagnosis by Doppler ultrasound; Cortocircuitos venosos portosistemicos intrahepaticos: diagnostico mediante ecografia Doppler

    Energy Technology Data Exchange (ETDEWEB)

    Garofano, M. P.; Medina, A.; Lopez, G.; Garrido, C. [Hospital Universitario Virgen de las Nieves. Granada (Spain)

    2001-07-01

    Intrahepatic portosystemic venous shunts are venous vascular lesions that allow intrahepatic portal vessels to communicate with hepatic veins. They may present in patients with portal hypertension or b discovered incidentally; it is considered that the latter may be congenital or acquired. A noninvasive methods. Doppler ultrasound aids in the diagnosis of these anomalous communications by providing images of the vessels and the direction, velocity and volume of the blood flow through the shunt. We present four cases of intrahepatic portosystemic venous shunt. (Author) 8 refs.

  3. Doppler Shift Oscillations from a Hot Line Observed by IRIS

    Science.gov (United States)

    Li, D.; Ning, Z. J.; Huang, Y.; Chen, N.-H.; Zhang, Q. M.; Su, Y. N.; Su, W.

    2017-11-01

    We present a detailed investigation of the Doppler shift oscillations in a hot loop during an M7.1 flare on 2014 October 27 observed by the Interface Region Imaging Spectrograph. The periodic oscillations are observed in the Doppler shift of Fe xxi 1354.09 Å (log T˜ 7.05), and the dominant period is about 3.1 minutes. However, such 3.1 minute oscillations are not found in the line-integrated intensity of Fe xxi 1354.09 Å, AIA EUV fluxes, or microwave emissions. Solar Dynamics Observatory/AIA and Hinode/XRT imaging observations indicate that the Doppler shift oscillations locate at the hot loop-top region (≥11 MK). Moreover, the differential emission measure results show that the temperature is increasing rapidly when the Doppler shift oscillates, but the number density does not exhibit the corresponding increases nor oscillations, implying that the flare loop is likely to oscillate in an incompressible mode. All of these facts suggest that the Doppler shift oscillations at the shorter period are most likely the standing kink oscillations in a flare loop. Meanwhile, a longer period of about 10 minutes is identified in the time series of Doppler shift and line-integrated intensity, GOES SXR fluxes, and AIA EUV light curves, indicating the periodic energy release in this flare, which may be caused by a slow mode wave.

  4. Thoracic electrical bioimpedance versus suprasternal Doppler in emergency care.

    Science.gov (United States)

    Elwan, Mohammed H; Hue, Jeremy; Green, Samira J; Eltahan, Salah M; Sims, Mark R; Coats, Timothy J

    2017-08-01

    There are a number of cardiac output (CO) monitors that could potentially be used in the ED. Two of the most promising methods, thoracic electrical bioimpedance and suprasternal Doppler, have not been directly compared. The aim of this study was to investigate the feasibility of CO monitoring using suprasternal Doppler and bioimpedance in emergency care and compare haemodynamic data obtained from both monitors. Haemodynamic measurements were made on the same group of patients using bioimpedance (Niccomo, Medis, Germany) and suprasternal Doppler (USCOM, Sydney, Australia). Usable CO data were obtained in 97% of patients by suprasternal Doppler and 87% by bioimpedance. The median CO obtained by Doppler was 3.4 L/min lower than bioimpedance. The stroke volume median was lower by 51 mL in Doppler. These two methods of non-invasive cardiac monitoring are not interchangeable. The results suggest that the choice of non-invasive cardiac monitor is important, but the grounds on which to make this choice are not currently clear. © 2017 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  5. Analysis of Radar Doppler Signature from Human Data

    Directory of Open Access Journals (Sweden)

    M. ANDRIĆ

    2014-04-01

    Full Text Available This paper presents the results of time (autocorrelation and time-frequency (spectrogram analyses of radar signals returned from the moving human targets. When a radar signal falls on the human target which is moving toward or away from the radar, the signals reflected from different parts of his body produce a Doppler shift that is proportional to the velocity of those parts. Moving parts of the body causes the characteristic Doppler signature. The main contribution comes from the torso which causes the central Doppler frequency of target. The motion of arms and legs induces modulation on the returned radar signal and generates sidebands around the central Doppler frequency, referred to as micro-Doppler signatures. Through analyses on experimental data it was demonstrated that the human motion signature extraction is better using spectrogram. While the central Doppler frequency can be determined using the autocorrelation and the spectrogram, the extraction of the fundamental cadence frequency using the autocorrelation is unreliable when the target is in the clutter presence. It was shown that the fundamental cadence frequency increases with increasing dynamic movement of people and simultaneously the possibility of its extraction is proportional to the degree of synchronization movements of persons in the group.

  6. Low-Frequency Gravitational Wave Searches Using Spacecraft Doppler Tracking

    Directory of Open Access Journals (Sweden)

    Armstrong J. W.

    2006-01-01

    Full Text Available This paper discusses spacecraft Doppler tracking, the current-generation detector technology used in the low-frequency (~millihertz gravitational wave band. In the Doppler method the earth and a distant spacecraft act as free test masses with a ground-based precision Doppler tracking system continuously monitoring the earth-spacecraft relative dimensionless velocity $2 Delta v/c = Delta u/ u_0$, where $Delta u$ is the Doppler shift and $ u_0$ is the radio link carrier frequency. A gravitational wave having strain amplitude $h$ incident on the earth-spacecraft system causes perturbations of order $h$ in the time series of $Delta u/ u_0$. Unlike other detectors, the ~1-10 AU earth-spacecraft separation makes the detector large compared with millihertz-band gravitational wavelengths, and thus times-of-flight of signals and radio waves through the apparatus are important. A burst signal, for example, is time-resolved into a characteristic signature: three discrete events in the Doppler time series. I discuss here the principles of operation of this detector (emphasizing transfer functions of gravitational wave signals and the principal noises to the Doppler time series, some data analysis techniques, experiments to date, and illustrations of sensitivity and current detector performance. I conclude with a discussion of how gravitational wave sensitivity can be improved in the low-frequency band.

  7. Clinical and nutritional implications of radiation enteritis

    Energy Technology Data Exchange (ETDEWEB)

    Beer, W.H.; Fan, A.; Halsted, C.H.

    1985-01-01

    The clinical and nutritional significance of radiation enteritis was assessed in eight patients with chronic diarrhea which followed curative doses of radiotherapy for pelvic malignancies. Steatorrhea, found in seven malnourished patients, was ascribed to ileal disease or previous surgery, or to bacterial contamination of the small intestine. Lactose intolerance, assessed by breath hydrogen excretion after oral lactose and by jejunal lactase levels, was found in six patients. In a subgroup of five patients, the administration of two different defined formula liquid diets by nasoduodenal infusion decreased fecal fluid and energy losses by about one-half. Compared to Vivonex-HN, the infusion of Criticare-HN was associated with greater likelihood of intestinal gas production but a three-fold greater utilization of protein. Intestinal malabsorption and malnutrition in radiation enteritis has diverse etiologies. Whereas nutritional support by liquid diet limits fecal fluid and energy losses, these diets differ significantly in clinical tolerance and biologic value.

  8. Enteral feeding practices in the NICU: results from a 2009 Neonatal Enteral Feeding Survey.

    Science.gov (United States)

    Gregory, Katherine E; Connolly, Teresa C

    2012-02-01

    : The purpose of this study was to examine the current management of the enteral feeding regimens of premature infants cared for in the neonatal intensive care unit (NICU). : The study included responses from 70 neonatal nurses who participated in a 2009 Neonatal Enteral Feeding Survey distributed electronically to the National Association of Neonatal Nurses membership. These respondents were representative of both the United States and Canada, with 29 US states represented. The majority of respondents (95.7%) reported current nursing employment in a level III NICU. : Survey research was used in this exploratory study. The survey, Enteral Tube Feeding Practices in the Neonatal Intensive Care Unit, was developed in collaboration with expert neonatal nurses and nutritionists, pilot tested, and distributed via electronic means. : Survey research was conducted according to the Dillman methodology. Data analysis included descriptive statistics and univariate analysis of variance assessing for significant differences in specific neonatal feeding practices reported. Thematic analysis was used to analyze the qualitative data reported. : The outcome measures included the survey responses to the questions asked about the implementation of an enteral feeding protocol and various aspects of enteral feeding practices in the NICU. : The majority of participants (60.9%) reported that an enteral feeding protocol was implemented in practice, but that it was inconsistently followed because of individual physician or nurse practice patterns, or highly individualized feeding plans required of specific clinical care needs of the patient. Respondents indicated that gestational age was the leading criteria used to initiate feedings, and patent ductus arteriosis treatment was the primary contraindication to enteral feedings. The leading factor reported to delay or alter enteral feedings was the presence of gastric residuals. Survey data indicated that other contraindicating factors to

  9. Collaborative Innovation for Entering Emerging Markets

    OpenAIRE

    Öhrwall Rönnbäck, Anna

    2010-01-01

    The aim of this paper is to investigate collaborative innovation in business networks for small environmental technology companies entering an emerging market (EM). Export of environmental technology solutions to emerging economies involves high investment opportunities and high growth potential, but also high risk. For example, large-scale demonstrator equipment proving the function of the environmental technology solution might be needed, which usually requires cooperation between several c...

  10. Calculation of the Doppler broadening function using Fourier analysis;Calculo da funcao de alargamento Doppler utilizando analise de Fourier

    Energy Technology Data Exchange (ETDEWEB)

    Goncalves, Alessandro da Cruz

    2010-07-01

    An efficient and precise method for calculation of Doppler broadening function is very important to obtain average group microscopic cross sections, self shielding factors, resonance integrals and others reactor physics parameter. In this thesis two different methods for calculation of Doppler broadening function and interference term will be presented. The main method is based on a new integral form for Doppler broadening function {psi}(x,{zeta}) which gives a mathematical interpretation of the approximation proposed by Bethe and Placzek, as the convolution of the Lorentzian function with a Gaussian function. This interpretation besides leading to a new integral form for {psi}(x,{zeta}), enables to obtain a simple analytic solution for the Doppler broadening function. (author)

  11. Enteral Nutrition in Dementia: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Joanne Brooke

    2015-04-01

    Full Text Available The aim of this systematic review is to evaluate the role of enteral nutrition in dementia. The prevalence of dementia is predicted to rise worldwide partly due to an aging population. People with dementia may experience both cognitive and physical complications that impact on their nutritional intake. Malnutrition and weight loss in dementia correlates with cognitive decline and the progress of the disease. An intervention for long term eating difficulties is the provision of enteral nutrition through a Percutaneous Endoscopic Gastrostomy tube to improve both nutritional parameters and quality of life. Enteral nutrition in dementia has traditionally been discouraged, although further understanding of physical, nutritional and quality of life outcomes are required. The following electronic databases were searched: EBSCO Host, MEDLINE, PubMed, Cochrane Database of Systematic Reviews and Google Scholar for publications from 1st January 2008 and up to and including 1st January 2014. Inclusion criteria included the following outcomes: mortality, aspiration pneumonia, pressure sores, nutritional parameters and quality of life. Each study included separate analysis for patients with a diagnosis of dementia and/or neurological disease. Retrospective and prospective observational studies were included. No differences in mortality were found for patients with dementia, without dementia or other neurological disorders. Risk factors for poor survival included decreased or decreasing serum albumin levels, increasing age or over 80 years and male gender. Evidence regarding pneumonia was limited, although did not impact on mortality. No studies explored pressure sores or quality of life.

  12. Enteral Nutrition in Dementia: A Systematic Review

    Science.gov (United States)

    Brooke, Joanne; Ojo, Omorogieva

    2015-01-01

    The aim of this systematic review is to evaluate the role of enteral nutrition in dementia. The prevalence of dementia is predicted to rise worldwide partly due to an aging population. People with dementia may experience both cognitive and physical complications that impact on their nutritional intake. Malnutrition and weight loss in dementia correlates with cognitive decline and the progress of the disease. An intervention for long term eating difficulties is the provision of enteral nutrition through a Percutaneous Endoscopic Gastrostomy tube to improve both nutritional parameters and quality of life. Enteral nutrition in dementia has traditionally been discouraged, although further understanding of physical, nutritional and quality of life outcomes are required. The following electronic databases were searched: EBSCO Host, MEDLINE, PubMed, Cochrane Database of Systematic Reviews and Google Scholar for publications from 1st January 2008 and up to and including 1st January 2014. Inclusion criteria included the following outcomes: mortality, aspiration pneumonia, pressure sores, nutritional parameters and quality of life. Each study included separate analysis for patients with a diagnosis of dementia and/or neurological disease. Retrospective and prospective observational studies were included. No differences in mortality were found for patients with dementia, without dementia or other neurological disorders. Risk factors for poor survival included decreased or decreasing serum albumin levels, increasing age or over 80 years and male gender. Evidence regarding pneumonia was limited, although did not impact on mortality. No studies explored pressure sores or quality of life. PMID:25854831

  13. A STUDY ON ROLE OF DOPPLER ULTRASOUND IN NORMAL AND HIGH-RISK PREGNANCIES WITH PERINATAL OUTCOME

    Directory of Open Access Journals (Sweden)

    Mozibur Rahman Laskar

    2016-09-01

    Full Text Available OBJECTIVES To evaluate the diagnostic value of various waveform of Doppler ultrasound of three vessels (uterine artery, middle cerebral artery and umbilical artery in high-risk pregnancies in compare to normal pregnancy related to perinatal outcome. MATERIALS AND METHODS 200 singleton pregnancies beyond 28 weeks of gestation were studied out of which 100 were normal and 100 were high-risk pregnancies with PIH and clinical suspicion of IUGR. Doppler examination was done after recording history, clinical ex and USG. RESULTS The PI, RI and S/D of Umbilical artery and Uterine artery were significantly higher in study group as compared to control group and the PI, RI and S/D of middle cerebral artery were significantly lower in study group as compared to control group. 70% of foetuses in study group had at least one adverse outcome in study group in contrast to only 10% of control group had adverse outcome. Doppler study of UA and UmbA together had a better sensitivity than individual vessel. The MCA/UmbA PI ratio of study group showed more foetuses to redistribute their cardiac output than the abnormal MCA PI or UmbA PI. The cerebroumbilical ratio provided a better predictor of high-risk pregnancies and adverse perinatal outcome than either MCA or UmbA. CONCLUSION Hence, we conclude that Doppler studies of multiple vessels in the foetoplacental circulation can help in the monitoring of compromised foetus and can help in predicting neonatal morbidity. This may be helpful in determining the optimal time of delivery in complicated pregnancies. ABBREVIATIONS UA-Uterine artery, UmbA-Umbilical artery, MCA-Middle cerebral artery, RI-Resistive index, PI-Pulsatility index, S/DSystolic/Diastolic ratio, IUGR-Intrauterine growth restriction, IUFD-Intrauterine fetal demise, LSCS-Lower segment caesarean section, SVD-Spontaneous vaginal delivery, PIH- Pregnancy-induced hypertension.

  14. The clinical significance of reversed flow in the main pulmonary artery detected by doppler color flow imaging.

    Science.gov (United States)

    Murata, I; Sonoda, M; Morita, T; Nakamura, F; Takenaka, K; Nagai, R

    2000-08-01

    Using Doppler color flow imaging, abnormal flow patterns were reported to occur with pulmonary artery (PA) dilation. We have frequently observed red signals in the main PA, suggesting reversed flow (RF) in patients without overt pulmonary hypertension. The clinical implication of these signals has not been extensively studied. We studied 191 of 412 patients referred for echocardiography (99 men and 92 women; mean +/- SD age, 62 +/- 13 years), in whom the main PA diameter had been adequately measured. If a red signal was observed by color flow imaging, a pulsed Doppler echocardiogram of the red signal was recorded simultaneously. The presence of the red signal was correlated with the PA diameter and the PA systolic pressure determined using the modified Bernoulli equation. In 54 patients who also underwent cardiac catheterization studies, the red signal was correlated with PA and pulmonary capillary wedge (PCW) pressures, and with pulmonary vascular resistance. Red signals adjacent to the medial PA border were detected in parallel with systolic blue signals in 127 patients (66%). Pulsed Doppler recordings revealed that they were caused by RF occurring immediately after the forward systolic signal and persisted in diastole. The PA diameter (28 +/- 4.8 mm) and the estimated PA systolic pressure (34 +/- 16 mm Hg) of patients with the RF signal were significantly greater (p < 0.001 and p < 0.05, respectively) than those of patients without the signal (22 +/- 2.5 mm and 28 +/- 6.0 mm Hg, respectively). Among patients who had hemodynamic studies, PA and PCW pressures were significantly higher (p < 0.05) in the 41 patients with the RF signal (22 +/- 12 mm Hg vs 15 +/- 2.6 mm Hg and 11 +/- 5.5 mm Hg vs 8 +/- 3.1 mm Hg, respectively). : RF signals in the main PA occur mostly as a result of PA dilation, which may be caused by primary pulmonary hypertension or chronic elevation of left atrial pressure in left-sided cardiac abnormalities.

  15. Abnormal thermography in Parkinson's disease.

    Science.gov (United States)

    Antonio-Rubio, I; Madrid-Navarro, C J; Salazar-López, E; Pérez-Navarro, M J; Sáez-Zea, C; Gómez-Milán, E; Mínguez-Castellanos, A; Escamilla-Sevilla, F

    2015-08-01

    An autonomic denervation and abnormal vasomotor reflex in the skin have been described in Parkinson's disease (PD) and might be evaluable using thermography with cold stress test. A cross-sectional pilot study was undertaken in 35 adults: 15 patients with PD and abnormal [(123)I]-metaiodobenzylguanidine cardiac scintigraphy and 20 healthy controls. Baseline thermography of both hands was obtained before immersing one in cold water (3 ± 1 °C) for 2 min. Continuous thermography was performed in: non-immersed hand (right or with lesser motor involvement) during immersion of the contralateral hand and for 6 min afterward; and contralateral immersed hand for 6 min post-immersion. The region of interest was the dorsal skin of the third finger, distal phalanx. PD patients showed a lower mean baseline hand temperature (p = 0.037) and greater thermal difference between dorsum of wrist and third finger (p = 0.036) and between hands (p = 0.0001) versus controls, regardless of the motor laterality. Both tests evidenced an adequate capacity to differentiate between groups: in the non-immersed hand, the PD patients did not show the normal cooling pattern or final thermal overshoot observed in controls (F = 5.29; p = 0.001), and there was an AUC of 0.897 (95%CI 0.796-0.998) for this cooling; in the immersed hand, thermal recovery at 6 min post-immersion was lesser in patients (29 ± 17% vs. 55 ± 28%, p = 0.002), with an AUC of 0.810 (95%CI 0.662-0.958). PD patients reveal abnormal skin thermal responses in thermography with cold stress test, suggesting cutaneous autonomic dysfunction. This simple technique may be useful to evaluate autonomic dysfunction in PD. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Three-dimensional power Doppler transanal ultrasonography, to monitor haemorrhoidal blood flow after Doppler-guided ALTA sclerosing therapy.

    Science.gov (United States)

    Miyamoto, H; Asanoma, M; Miyamoto, H; Takasu, C; Shimada, M

    2013-02-01

    The study aimed to use power Doppler imaging (PDI) transanal ultrasonography to produce three-dimensional power Doppler angiography images of haemorrhoidal tissue and to monitor the effects of Doppler-guided aluminium potassium sulfate and tannic acid (DGALTA) sclerotherapy. Ninety-six haemorrhoids in 43 patients were examined using PDI transanal ultrasonography, and DGALTA sclerotherapy was performed from April 2011 to April 2012. DGALTA sclerotherapy was conducted using a four-step injection process with pulse wave Doppler ultrasound under perianal local anaesthesia. A three-dimensional power Doppler angiography image of the blood flow in haemorrhoidal tissue was produced using PDI transanal ultrasonography. The cross-sectional area of blood flow in the haemorrhoidal tissue (PDI area) significantly decreased after DGALTA sclerotherapy. The PDI areas in the preoperative state and 1 and 3 months after treatment were 0.35±0.27, 0.03±0.05 and 0.04±0.05 cm(2) (Ppower Doppler angiography image of the haemorrhoidal tissue was technically possible and showed blood flow in the haemorrhoidal tissue to be significantly decreased after DGALTA sclerotherapy. © 2012 The Authors. Colorectal Disease © 2012 The Association of Coloproctology of Great Britain and Ireland.

  17. Enteral ecoimmunonutrition reduced enteral permeability and serum ghrelin activity in severe cerebral stroke patients with lung infection.

    Science.gov (United States)

    Xu, Xiao-Di; Shao, Feng

    2015-01-01

    The study analyzed how enteral ecoimmunonutrition, which comprises probiotics, glutamine, fish oil, and Enteral Nutritional Suspension (TPF), can impact on the enteral permeability and serum Ghrelin activity in severe cerebral stroke patients with lung infection. Among 190 severe cerebral stroke patients with tolerance to TPF, they were randomized into control and treatment groups after antibiotics treatment due to lung infections. There were 92 patients in the control group and 98 patients in treatment group. The control group was treated with TPF and the treatment group was treated with enteral ecoimmunonutrition, which comprises probiotics, glutamine, fish oil, and Enteral Nutritional Suspension. All patients received continuous treatments through nasoenteral or nasogastric tubes. 7, 14, and 21 days after the treatments, the enteral tolerance to nutrition was observed in both groups. The tests included abdominal pain, bloating, diarrhea, and lactulose/mannitol (L/M) ratio. Serum Ghrelin levels were determined by ELISA. The incidence of abdominal pain, bloating, diarrhea was lower in the treatment group and enteral tolerance to nutrition was also superior to the control group. No difference in serum Ghrelin level was observed between the control and treatment groups with enteral intolerance to nutrition. However, in patients with enteral tolerance to nutrition, the treatment group showed lower enteral nutrition and lower enteral permeability compared to the control group. In severe cerebral stroke patients with lung infection, enteral ecoimmunonutrition after antibiotics treatment improved enteral tolerance to nutrition and reduced enteral permeability; meanwhile, it lowered the serum Ghrelin activity, which implied the high serum Ghrelin reduces enteral permeability.

  18. The recondite intricacies of Zeeman Doppler mapping

    Science.gov (United States)

    Stift, M. J.; Leone, F.; Cowley, C. R.

    2012-02-01

    We present a detailed analysis of the reliability of abundance and magnetic maps of Ap stars obtained by Zeeman Doppler mapping (ZDM). It is shown how they can be adversely affected by the assumption of a mean stellar atmosphere instead of appropriate 'local' atmospheres corresponding to the actual abundances in a given region. The essence of the difficulties was already shown by Chandrasekhar's picket-fence model. The results obtained with a suite of Stokes codes written in the ADA programming language and based on modern line-blanketed atmospheres are described in detail. We demonstrate that the high metallicity values claimed to have been found in chemically inhomogeneous (horizontally and vertically) Ap star atmospheres would lead to local temperature structures, continuum and line intensities, and line shapes that differ significantly from those predicted by a mean stellar atmosphere. Unfortunately, past applications of ZDM have consistently overlooked the intricate aspects of metallicity with their all-pervading effects. The erroneous assumption of a mean atmosphere for a spotted star can lead to phase-dependent errors of uncomfortably large proportions at varying wavelengths both in the Stokes I and V profiles, making precise mapping of abundances and magnetic field vectors largely impossible. The relation between core and wings of the Hβ line changes, too, with possible repercussions on the determination of gravity and effective temperature. Finally, a ZDM analysis of the synthetic Stokes spectra of a spotted star reveals the disturbing differences between the respective abundance maps based on a mean atmosphere on the one hand, and on appropriate 'local' atmospheres on the other. We then discuss what this all means for published ZDM results. Our discussion makes it clear that realistic local atmospheres must be used, especially if credible small-scale structures are to be obtained. Recondite: dealing with very profound, difficult or abstruse subject

  19. Doppler optical coherence tomography in cardiovascular physiology

    Science.gov (United States)

    Bonesi, M.; Meglinski, I.; Matcher, S.

    2008-09-01

    The study of flow dynamics in complex geometry vessels is highly important in many biomedical applications where the knowledge of the mechanic interactions between the moving fluid and the housing media plays a key role for the determination of the parameters of interest, including the effect of blood flow on the possible rupture of atherosclerotic plaques. Doppler Optical Coherence Tomography (DOCT), as a functional extension of Optical Coherence Tomography (OCT), is an optic, non-contact, non-invasive technique able to achieve detailed analysis of the flow/vessel interactions. It allows simultaneous high resolution imaging (10 μm typical) of the morphology and composition of the vessel and determination of the flow velocity distribution along the measured cross-section. We applied DOCT system to image high-resolution one-dimensional and multi-dimensional velocity distribution profiles of Newtonian and non-Newtonian fluids flowing in vessels with complex geometry, including Y-shaped and T-shaped vessels, vessels with aneurism, bifurcated vessels with deployed stent and scaffolds. The phantoms were built to mimic typical shapes of human blood vessels, enabling preliminary analysis of the interaction between flow dynamics and the (complex) geometry of the vessels and also to map the related velocity profiles at several inlet volume flow rates. Feasibility studies for quantitative observation of the turbulence of flows arising within the complex geometry vessels are discussed. In addition, DOCT technique was also applied for monitoring cerebral mouse blood flow in vivo. Two-dimensional DOCT images of complex flow velocity profiles in blood vessel phantoms and in vivo sub-cranial mouse blood flow velocities distributions are presented.

  20. Doppler optical coherence tomography in cardiovascular applications

    Science.gov (United States)

    Bonesi, M.; Matcher, S.; Meglinski, I.

    2010-06-01

    The study of flow dynamics in complex geometry vessels is highly important in various biomedical applications where the knowledge of the mechanic interactions between the moving fluid and the housing media plays a key role for the determination of the parameters of interest, including the effect of blood flow on the possible rupture of atherosclerotic plaques. Doppler Optical Coherence Tomography (DOCT), as a functional extension of Optical Coherence Tomography (OCT), is an optic, non-contact, noninvasive technique able to achieve detailed analysis of the flow/vessel interactions. It allows simultaneous high resolution imaging (˜10 µm typical) of the morphology and composition of the vessel and determination of the flow velocity distribution along the measured cross-section. We applied DOCT system to image high-resolution one-dimensional and multi-dimensional velocity distribution profiles of Newtonian and non-Newtonian fluids flowing in vessels with complex geometry, including Y-shaped and T-shaped vessels, vessels with aneurism, bifurcated vessels with deployed stent and scaffolds. The phantoms were built to mimic typical shapes of human blood vessels, enabling preliminary analysis of the interaction between flow dynamics and the (complex) geometry of the vessels and also to map the related velocity profiles at several inlet volume flow rates. Feasibility studies for quantitative observation of the turbulence of flows arising within the complex geometry vessels are discussed. In addition, DOCT technique was also applied for monitoring cerebral mouse blood flow in vivo. Two-dimensional DOCT images of complex flow velocity profiles in blood vessel phantoms and in vivo sub-cranial mouse blood flow velocities distributions are presented.

  1. Abnormal visuomotor processing in schizophrenia

    Directory of Open Access Journals (Sweden)

    Siân E. Robson

    2016-01-01

    Full Text Available Subtle disturbances of visual and motor function are known features of schizophrenia and can greatly impact quality of life; however, few studies investigate these abnormalities using simple visuomotor stimuli. In healthy people, electrophysiological data show that beta band oscillations in sensorimotor cortex decrease during movement execution (event-related beta desynchronisation (ERBD, then increase above baseline for a short time after the movement (post-movement beta rebound (PMBR; whilst in visual cortex, gamma oscillations are increased throughout stimulus presentation. In this study, we used a self-paced visuomotor paradigm and magnetoencephalography (MEG to contrast these responses in patients with schizophrenia and control volunteers. We found significant reductions in the peak-to-peak change in amplitude from ERBD to PMBR in schizophrenia compared with controls. This effect was strongest in patients who made fewer movements, whereas beta was not modulated by movement in controls. There was no significant difference in the amplitude of visual gamma between patients and controls. These data demonstrate that clear abnormalities in basic sensorimotor processing in schizophrenia can be observed using a very simple MEG paradigm.

  2. Lower Extremity Abnormalities in Children.

    Science.gov (United States)

    Rerucha, Caitlyn M; Dickison, Caleb; Baird, Drew C

    2017-08-15

    Leg and foot problems in childhood are common causes of parental concern. Rotational problems include intoeing and out-toeing. Intoeing is most common in infants and young children. Intoeing is caused by metatarsus adductus, internal tibial torsion, and femoral anteversion. Out-toeing is less common than intoeing and occurs more often in older children. Out-toeing is caused by external tibial torsion and femoral retroversion. Angular problems include genu varum (bowleg) and genu valgum (knock knee). With pes planus (flatfoot), the arch of the foot is usually flexible rather than rigid. A history and physical examination that include torsional profile tests and angular measurements are usually sufficient to evaluate patients with lower extremity abnormalities. Most children who present with lower extremity problems have normal rotational and angular findings (i.e., within two standard deviations of the mean). Lower extremity abnormalities that are within normal measurements resolve spontaneously as the child grows. Radiologic studies are not routinely required, except to exclude pathologic conditions. Orthotics are not beneficial. Orthopedic referral is often not necessary. Rarely, surgery is required in patients older than eight years who have severe deformities that cause dysfunction.

  3. Prevalence and consequences of chromosomal abnormalities in Canadian commercial swine herds.

    Science.gov (United States)

    Quach, Anh T; Revay, Tamas; Villagomez, Daniel A F; Macedo, Mariana P; Sullivan, Alison; Maignel, Laurence; Wyss, Stefanie; Sullivan, Brian; King, W Allan

    2016-09-12

    Structural chromosome abnormalities are well known as factors that reduce fertility rate in domestic pigs. According to large-scale national cytogenetic screening programs that are implemented in France, it is estimated that new chromosome abnormalities occur at a rate of 0.5 % in fertility-unproven boars. This work aimed at estimating the prevalence and consequences of chromosome abnormalities in commercial swine operations in Canada. We found pig carriers at a frequency of 1.64 % (12 out of 732 boars). Carrier pigs consistently showed lower fertility values. The total number of piglets born for litters from carrier boars was between 4 and 46 % lower than the herd average. Similarly, carrier boars produced litters with a total number of piglets born alive that was between 6 and 28 % lower than the herd average. A total of 12 new structural chromosome abnormalities were identified. Reproductive performance is significantly reduced in sires with chromosome abnormalities. The incidence of such abnormal sires appears relatively high in populations without routine cytogenetic screening such as observed for Canada in this study. Systematic cytogenetic screening of potential breeding boars would minimise the risk of carriers of chromosome aberrations entering artificial insemination centres. This would avoid the large negative effects on productivity for the commercial sow herds and reduce the risk of transmitting abnormalities to future generations in nucleus farms.

  4. The significance of inadequate transcranial Doppler studies in children with sickle cell disease.

    Directory of Open Access Journals (Sweden)

    Simon Greenwood

    Full Text Available Sickle cell disease (SCD is a common cause of cerebrovascular disease in childhood. Primary stroke prevention is effective using transcranial Doppler (TCD scans to measure intracranial blood velocities, and regular blood transfusions or hydroxycarbamide when these are abnormal. Inadequate TCD scans occur when it is not possible to measure velocities in all the main arteries. We have investigated the prevalence and significance of this in a retrospective audit of 3915 TCD scans in 1191 children, performed between 2008 and 2015. 79% scans were normal, 6.4% conditional, 2.8% abnormal and 12% inadequate. 21.6% of 1191 patients had an inadequate scan at least once. The median age of first inadequate scan was 3.3 years (0.7-19.4, with a U-shaped frequency distribution with age: 28% aged 2-3 years, 3.5% age 10 years, 25% age 16 years. In young children reduced compliance was the main reason for inadequate TCDs, whereas in older children it was due to a poor temporal ultrasound window. The prevalence of inadequate TCD was 8% in the main Vascular Laboratory at King's College Hospital and significantly higher at 16% in the outreach clinics (P<0.0001, probably due to the use of a portable ultrasound machine. Inadequate TCD scans were not associated with underlying cerebrovascular disease.

  5. Transcranial Doppler sonography in children: Review of a seven-year experience

    Energy Technology Data Exchange (ETDEWEB)

    Hirsch, Wolfgang; Hiebsch, Wolfgang; Teichler, Heike; SchlUeter, Andreas

    2002-06-01

    AIM: We report the use of transcranial Doppler sonography (TCD) examinations in children (mean age 12.7 years; range 0.5-18 years) without an open fontanelle, using TCD equipment with a 2 MHz pulse wave transducer. Our results over a 7-year period are described. MATERIAL AND METHODS: A total of 858 children were referred from the paediatric outpatient department. All patients were divided into three groups according to the reason for referral. RESULTS: We found positive pathological results in the following: (1) headache and orthostatic dysregulation (0.4%, three out of 728); (2) acute neurological symptoms (5.4%, six out of 112); (3) other indications (22.2%, four out of 18). The positive predictive value of finding an abnormality was very low (0.50) . CONCLUSION: TCD examination is ineffective in children with non-specific headache or orthostatic dysregulation due to the specific limitations of this method. We found a higher percentage of abnormal results in children referred for other indications. However, since these children usually undergo MR imaging (and MR angiography, if necessary), in our opinion the TCD examination does not add any additional information. The value of TCD in children is not in the primary diagnosis of disease but in the follow up of known vascular processes (e.g. stenoses) or in chronic diseases including angiitis and sickle cell disease. Hirsch, W. et al. (2002)

  6. Enteral iron supplementation in preterm and low birth weight infants.

    Science.gov (United States)

    Mills, Ryan John; Davies, Mark W

    2012-03-14

    Preterm infants are at risk of exhausting their body iron stores much earlier than healthy term newborns. It is widespread practice to give enteral iron supplementation to preterm and low birth weight infants to prevent iron deficiency anaemia. However, it is unclear whether supplementing preterm and low birth weight infants with iron improves growth and neurodevelopment. It is suspected that excess exogenous iron can contribute to oxidative injury in preterm babies, causing or exacerbating conditions such as necrotising enterocolitis and retinopathy of prematurity. Additionally, the optimal dose and timing of commencement and cessation of iron supplementation are uncertain. To evaluate the effect of prophylactic enteral iron supplementation on growth and neurodevelopmental outcomes in preterm and low birth weight infants. The secondary objectives were to determine whether iron supplementation results in improved haematological parameters and prevents other causes of morbidity and mortality. We used the standard search strategy of the Cochrane Neonatal Review Group. We searched Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 8), MEDLINE (1951 to August 2011), CINAHL (1982 to August 2011) and conference proceedings and previous reviews. Randomised controlled trials (RCTs) and quasi-randomised trials that compared enteral iron supplementation with no iron supplementation, or different regimens of enteral iron supplementation in preterm or low birth weight infants or both. We extracted data using the standard methods of the Cochrane Neonatal Review Group. Both review authors separately evaluated trial quality and data extraction. We synthesised data using risk ratios (RRs), risk differences (RDs) and weighted mean differences (WMDs). Where data about the methodology and results or both were lacking, we made an attempt to contact the study authors for further information. We included twenty-six studies (2726 infants) in the

  7. Morphologic and functional assessment of hemodialysis arteriovenous fistula with duplex doppler sonography

    Energy Technology Data Exchange (ETDEWEB)

    Cho, On Koo; Kim, Yong Soo; Rhim, Hyun Chul; Koh, Byung Hee; Kim, Bong Soo; Song, Soon Young; Park, Chan Hyun [Hanyang University College of Medicine, Seoul (Korea, Republic of)

    2001-03-15

    The pattern of morphologic and functional status of the hemodialysis AV fistula was studied using doppler ultrasound to define the useful parameter and its normal range for detecting the initial dysfunctional. Sixty patients of chronic renal failure with radial artery-cephalic vein fistula for hemodialysis (50 clinically normal and 10 clinically abnormal functioning AV fistula) were studied by duplex ultrasound. The examination followed the feeding artery to the draining vein and observed the morphology and waveform of the vessels. Peak systolic velocity (PSV), End diastolic velocity (EDV) and Systolic/Diastolic ratio (S/D ratio) were measured in the feeding artery. In the draining vein, peak velocity was measured and the presence of arterial pulsation was observed. Normal range of these measuring parameters and its significance and reliability for detecting dysfunction AV fistula were studied. In normally functioning fistula, waveforms of flow in the feeding artery were monophasic, with PSV 0.5-3.48 m/sec (average 1.75 {+-} 0.79 m/sec), EDV 0.2-1.47 m/sec (average 0.82 {+-} 0.41 m/sec) and S/D ratio 1.44-3.48 (average 2.34 {+-} 0.56). The draining vein showed components of arterial pulsations with peak velocity of 0.21-1.20 m/sec (average 0.54 {+-} 0.23 m/sec). Of the 10 clinically dysfunctional AV fistula, two cases had arteriosclerous vessel wall calcification and showed normal function on doppler sonography. Two cases of focal stenotic lesion of the draining vein showed significantly increased PSV which were more than 4.0 m/sec. Six cases of venous thrombosis showed a high resistance pattern of reversed diastolic flow with a measured S/D ratio of more than 4.0 and the absence of flow was noted within the draining S/D ratio was statically very reliable parameter (P=0.003) for defining normal and abnormal functioning AV fistula, however PSV and EDVV were unreliable (P=0.459). Duplex ultrasound is a useful diagnostic method for interpretating function of the

  8. Enteral nutrition. Potential complications and patient monitoring.

    Science.gov (United States)

    Kohn, C L; Keithley, J K

    1989-06-01

    Enteral feedings are safely tolerated by most patients. When complications occur, gastrointestinal disturbances are most frequently encountered, followed by mechanical and metabolic complications. Nurses can prevent many of the problems associated with enteral feeding through careful monitoring. Based on the current literature, the authors make the following recommendations: 1. All patients receiving tube feedings should be placed on a protocol that provides guidelines for (a) confirming correct tube placement; (b) preventing/managing tube obstruction; (c) handling and selecting formulas; (d) administering formulas; and (e) monitoring patients. 2. Fine-bore tubes are easily misplaced or dislodged; ensure correct positioning both before and during feeding. Food coloring should be added to all feedings to help detect aspiration/tube displacement. 3. Multiple factors can cause diarrhea in tube-fed patients and, therefore, require periodic assessment. These factors include concomitant drug therapy; malnutrition/hypoalbuminemia; formula-related factors (for example, lactose content, osmolality); and bacterial contamination. 4. Urine sugar and acetone levels should be checked every 6 hours (until stable). Vital signs and fluid intake and output should be determined every 8 hours, and weight should be measured on a daily basis. Serum electrolytes, blood urea nitrogen, and glucose levels should be determined daily, until serum levels stabilize. Weekly measurements of trace elements should be made to ensure adequate mineral replacement. 5. Use a controller pump to administer continuous feedings at a constant rate or to administer formulas that are viscous. Flush feeding tubes with water every 4 hours during continuous feedings, after giving intermittent feedings, after giving medications, and after checking for gastric residuals. If tube obstruction occurs, attempt to irrigate the tube with either water or cola. 6. Select feedings that contain appropriate nutrient sources

  9. Prediction of enteric methane emissions from cattle.

    Science.gov (United States)

    Moraes, Luis E; Strathe, Anders B; Fadel, James G; Casper, David P; Kebreab, Ermias

    2014-07-01

    Agriculture has a key role in food production worldwide and it is a major component of the gross domestic product of several countries. Livestock production is essential for the generation of high quality protein foods and the delivery of foods in regions where animal products are the main food source. Environmental impacts of livestock production have been examined for decades, but recently emission of methane from enteric fermentation has been targeted as a substantial greenhouse gas source. The quantification of methane emissions from livestock on a global scale relies on prediction models because measurements require specialized equipment and may be expensive. The predictive ability of current methane emission models remains poor. Moreover, the availability of information on livestock production systems has increased substantially over the years enabling the development of more detailed methane prediction models. In this study, we have developed and evaluated prediction models based on a large database of enteric methane emissions from North American dairy and beef cattle. Most probable models of various complexity levels were identified using a Bayesian model selection procedure and were fitted under a hierarchical setting. Energy intake, dietary fiber and lipid proportions, animal body weight and milk fat proportion were identified as key explanatory variables for predicting emissions. Models here developed substantially outperformed models currently used in national greenhouse gas inventories. Additionally, estimates of repeatability of methane emissions were lower than the ones from the literature and multicollinearity diagnostics suggested that prediction models are stable. In this context, we propose various enteric methane prediction models which require different levels of information availability and can be readily implemented in national greenhouse gas inventories of different complexity levels. The utilization of such models may reduce errors

  10. Campylobacter enteritis: early diagnosis with Gram's stain.

    Science.gov (United States)

    Ho, D D; Ault, M J; Ault, M A; Murata, G H

    1982-10-01

    Campylobacter jejuni has become one of the most important causes of infectious diarrhea in the United States. We examined the utility of Gram's stain of stool for the rapid presumptive diagnosis of Campylobacter enteritis in a large, urban hospital and found that this test has a sensitivity of 43.5% and a specificity of 99.4%. We believe that Gram's stain of stool could be used to direct the early management of up to one half of patients infected with this pathogen.

  11. Enteric methane emissions from German pigs

    DEFF Research Database (Denmark)

    Dämmgen, Ulrich; Schulz, Joachim; Klausing, Heinrich Kleine

    2012-01-01

    . Meanwhile numerous experimental data on methane emissions from enteric fermentation is available in Germany and abroad; the results are compiled in this work. These results also allow for a description of transformation processes in the hind gut and a subsequent establishment of models that relate emissions...... to feed and performance data. The model by Kirchgeßner et al. (1995) is based on German experimental data and reflects typical national diet compositions. It is used to quantify typical emissions and methane conversion ratios. The results agree with other experimental findings at home and abroad...

  12. [ZINK IS ACTIVATOR OF ENTERAL CALCIUM METABOLISM].

    Science.gov (United States)

    Polyakova, E P; Ksenofontov, D A; Revyakin, A O; Ivanov, A A

    2015-01-01

    Experiments on goats and rabbits showed that zinc supplement to the diet leads to calcium concentration rise in muscle, bone and blood of animals. However, this rise was not adequate to increase in.zinc consumption. The bulk of alimentary zinc stayed in soluble fraction, dense endogen fraction and infusoria fraction of digesta and stimulated calcium release from food particles, it's accumulation in digesta fractions and calcium utilization on the whole. Authors estimate animal digesta as homeostatic, spatial organized, endogenic formation in which zinc and calcium are functionally dependent through enteral mucosa.

  13. CHROMOSOMAL ABNORMALITIES IN PATIENTS WITH RECURRENT MISCARRIAGE

    Directory of Open Access Journals (Sweden)

    Daniela Mierla

    2012-06-01

    Full Text Available Chromosomal abnormalities are involved in the etiology of recurrent spontaneous pregnancy loss and sub-fertility. The purpose of this study was to determine the frequency and contribution of chromosomal abnormalities in recurrent miscarriages. The results obtained and literature review are helpful in understanding the importance of cytogenetics analysis of female infertility. To investigate the distribution of chromosomal abnormalities in the Romanian population with recurrent miscarriage, karyotype analysis by G-banding was performed from peripheral blood in 967 women infertility. Results: Chromosomal abnormalities were found to 79 women (8,17%. The percentage of chromosomal abnormalities in the studied population correlates with the data in the literature. Chromosomal abnormalities could play the important role in etiology of infertility and are more frequently detected in this group of patients compared to general population. In the infertile couples balanced chromosomal abnormalities are the main cause of spontaneous abortions.

  14. Neonatal pig brain: lack of heating during Doppler US.

    Science.gov (United States)

    Taylor, G A; Barnewolt, C E; Dunning, P S

    1998-05-01

    To evaluate potential local brain-heating effects of Doppler ultrasound (US) at high power output settings. After craniotomy, a temperature probe was inserted into deep white matter or basal ganglia in 12 anesthetized newborn piglets. The range gate and focal zone were placed directly over the temperature sensor. Brain and core (rectal) temperatures were measured before and during 5 minutes of continuous transdural duplex or color Doppler US, with transmitter power output settings of less than 500 mW in situ spatial peak temporal average or less than 800 mW in situ spatial peak temporal average. Temperature also was measured during administration of a US contrast agent with duplex US at less than 500 mW in situ spatial peak temporal average and after death at the same output setting. Maximal differences between the baseline and the post-US temperatures were, on average, less than 0.3 degree C (P > .5) and were highly correlated with changes in core temperature (r = .9, P heating during pulsed Doppler US (P > .6). There was no association between an increase in estimated power output and brain temperature change (P = .9). In addition, brain ischemia (postmortem exposure) was not associated with focal brain heating during pulsed Doppler US. Transfontanellar Doppler US alone or with administration of a contrast agent does not produce statistically significant focal brain heating at high transmitter power levels.

  15. High-resolution Doppler model of the human gait

    Science.gov (United States)

    Geisheimer, Jonathan L.; Greneker, Eugene F., III; Marshall, William S.

    2002-07-01

    A high resolution Doppler model of the walking human was developed for analyzing the continuous wave (CW) radar gait signature. Data for twenty subjects were collected simultaneously using an infrared motion capture system along with a two channel 10.525 GHz CW radar. The motion capture system recorded three-dimensional coordinates of infrared markers placed on the body. These body marker coordinates were used as inputs to create the theoretical Doppler output using a model constructed in MATLAB. The outputs of the model are the simulated Doppler signals due to each of the major limbs and the thorax. An estimated radar cross section for each part of the body was assigned using the Lund & Browder chart of estimated body surface area. The resultant Doppler model was then compared with the actual recorded Doppler gait signature in the frequency domain using the spectrogram. Comparison of the two sets of data has revealed several identifiable biomechanical features in the radar gait signature due to leg and body motion. The result of the research shows that a wealth of information can be unlocked from the radar gait signature, which may be useful in security and biometric applications.

  16. Is middle cerebral artery Doppler related to neonatal and 2-year infant outcome in early fetal growth restriction?

    Science.gov (United States)

    Stampalija, Tamara; Arabin, Birgit; Wolf, Hans; Bilardo, Caterina M; Lees, Christoph

    2017-05-01

    umbilicocerebral ratio Z-score at inclusion were associated with 2 year survival with normal neurodevelopmental outcome (odds ratio, 1.33; 95% confidence interval, 1.03-1.72, and odds ratio, 0.88; 95% confidence interval, 0.78-0.99, respectively) as were gestation at delivery and birthweight p50 ratio (odds ratio, 1.41; 95% confidence interval, 1.20-1.66, and odds ratio, 1.86; 95% confidence interval, 1.33-2.60, respectively). When comparing cerebroplacental ratio against umbilicocerebral ratio, the incremental range of the cerebroplacental ratio tended toward zero, whereas the umbilicocerebral ratio tended toward infinity as the values became more abnormal. In a monitoring protocol based on ductus venosus and cardiotocography in early fetal growth restriction (26 +0 -31 +6 weeks of gestation), the impact of middle cerebral artery Doppler and its ratios on outcome is modest and less marked than birthweight and delivery gestation. It is unlikely that middle cerebral artery Doppler and its ratios are informative in optimizing the timing of delivery in fetal growth restriction before 32 weeks of gestation. The umbilicocerebral ratio allows for a better differentiation in the abnormal range than the cerebroplacental ratio. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Ultrastructural and cellular basis for the development of abnormal myocardial mechanics during the transition from hypertension to heart failure.

    Science.gov (United States)

    Shah, Sanjiv J; Aistrup, Gary L; Gupta, Deepak K; O'Toole, Matthew J; Nahhas, Amanda F; Schuster, Daniel; Chirayil, Nimi; Bassi, Nikhil; Ramakrishna, Satvik; Beussink, Lauren; Misener, Sol; Kane, Bonnie; Wang, David; Randolph, Blake; Ito, Aiko; Wu, Megan; Akintilo, Lisa; Mongkolrattanothai, Thitipong; Reddy, Mahendra; Kumar, Manvinder; Arora, Rishi; Ng, Jason; Wasserstrom, J Andrew

    2014-01-01

    Although the development of abnormal myocardial mechanics represents a key step during the transition from hypertension to overt heart failure (HF), the underlying ultrastructural and cellular basis of abnormal myocardial mechanics remains unclear. We therefore investigated how changes in transverse (T)-tubule organization and the resulting altered intracellular Ca(2+) cycling in large cell populations underlie the development of abnormal myocardial mechanics in a model of chronic hypertension. Hearts from spontaneously hypertensive rats (SHRs; n = 72) were studied at different ages and stages of hypertensive heart disease and early HF and were compared with age-matched control (Wistar-Kyoto) rats (n = 34). Echocardiography, including tissue Doppler and speckle-tracking analysis, was performed just before euthanization, after which T-tubule organization and Ca(2+) transients were studied using confocal microscopy. In SHRs, abnormalities in myocardial mechanics occurred early in response to hypertension, before the development of overt systolic dysfunction and HF. Reduced longitudinal, circumferential, and radial strain as well as reduced tissue Doppler early diastolic tissue velocities occurred in concert with T-tubule disorganization and impaired Ca(2+) cycling, all of which preceded the development of cardiac fibrosis. The time to peak of intracellular Ca(2+) transients was slowed due to T-tubule disruption, providing a link between declining cell ultrastructure and abnormal myocardial mechanics. In conclusion, subclinical abnormalities in myocardial mechanics occur early in response to hypertension and coincide with the development of T-tubule disorganization and impaired intracellular Ca(2+) cycling. These changes occur before the development of significant cardiac fibrosis and precede the development of overt cardiac dysfunction and HF.

  18. Transcranial Doppler ultrasound for cerebral perfusion.

    Science.gov (United States)

    Jørgensen, L G

    1995-01-01

    By providing a non-invasive method for continuous display of mean flow velocity (Vmean) in the cerebral arteries, transcranial Doppler (TCD) ultrasound supplements evaluation of cerebral perfusion. Dynamic exercise increases middle cerebral artery (MCA) Vmean from approximately 55 to 65 cm s-1 dependent on work rate, and even more when corrected for changes of the arterial carbon dioxide tension. Evaluation of Vmean corresponds to that of cerebral blood flow as determined with the 133Xenon clearance technique, and reflects regional cortical regulation of the active muscles with important afferent nervous influence. Concomitant increases of mean arterial pressure (MAP) and heart rate is only of minor importance as illustrated during static exercise and post-exercise muscle ischaemia, where Vmean is not significantly elevated. During sustained head-up tilt, the Vmean remained unchanged at a MAP approximately 83 mmHg. Below this level, it decreased in parallel with MAP until MAP reached 50 mmHg. At an even lower MAP, Vmean seemed to approach a lower limit approximately 25 cm s-1, but at a diastolic pressure of 21 mmHg there was no flow in the MCA. Conversely, during post-exercise muscle ischemia, an increase in MAP to 140 mmHg did not influence Vmean. This is in contrast to patients operated for carotid artery stenosis and who develop ipsilateral headache. In these patients the ipsilateral MCA Vmean changed in parallel with MAP, and autoregulation was re-established only after one to two weeks. In patients with severe carotid stenosis and poor collateral circulation, the CO2-reactivity as expressed by Vmean was the lowest, and could be negative on the ipsilateral side. During carotid endarterectomy, a Vmean clamp/Vmean pre-clamp ratio below 0.6 identified patients with a cerebral blood flow below 20 ml 100 g-1 min-1. Furthermore, when the ratio was below 0.4 pathological electroenchephalographic changes developed. Thus, Vmean of the large basal cerebral arteries

  19. The Enteric Nervous System in Intestinal Inflammation

    Directory of Open Access Journals (Sweden)

    Keith A Sharkey

    1996-01-01

    Full Text Available Since about the 1950s nerves in the wall of the intestine have been postulated to play a role in the pathogenesis of inflammatory bowel disease (IBD. Human and animal studies examining the role of nerves in intestinal inflammation are the focus of this review. Consideration is given to two possible ways that nerves are involved in IBD. First, nerves may play a role in the development or maintenance of inflammation through local release of transmitters. Second, once initiated (by whatever means, the processes of inflammation may disrupt the normal pattern of innervation and the interactions of nerves and their target tissues. Many of the functional disturbances observed in IBD are likely due to an alteration in the enteric nervous system either structurally through disruptions of nerve-target relationships or by modifications of neurotransmitters or their receptors. Finally, it appears that the enteric nervous system may be a potential therapeutic target in IBD and that neuroactive drugs acting locally can represent useful agents in the management of this disease.

  20. Administration of antiretroviral medication via enteral tubes.

    Science.gov (United States)

    Prohaska, Emily S; King, Allison R

    2012-12-15

    Case reports and other published or manufacturer-provided data on the administration of antiretroviral agents through enteral feeding tubes are reviewed. There is very limited published evidence to guide clinicians in the delivery of therapies for human immunodeficiency virus (HIV) infection by feeding tubes, especially crushed tablets and capsule contents. A search of the primary literature (through February 2012) identified a total of nine articles describing the delivery of highly active antiretroviral therapy (HAART) agents via gastrostomy (G), jejunostomy, and other feeding tubes; correspondence with pharmaceutical manufacturers yielded additional information. Most of the published evidence (from two prospective studies, one retrospective study, and six case reports) pertains to the treatment of HIV-infected children (33 of 40 cases). Although not a primary endpoint of any of the reviewed studies, viral suppression was documented in 29 of the 40 patients referenced in the reviewed articles. Manufacturer-provided information indicates that crushed darunavir tablets in suspension, as well as oral solutions of ritonavir and lopinavir-ritonavir, can be administered through G-tubes without significant loss of therapeutic efficacy. Data regarding enteral feeding tube administration are available for 63% of commercially available oral HAART agents and are primarily limited to case reports specific to the pediatric population.

  1. [Our experience with ambulatory enteral nutrition].

    Science.gov (United States)

    Orduña, R M; Giménez Martínez, R; Valdivia Garvayo, M; Ruiz Santa-Olalla, A T; Roca Fernández-Castanys, E; Pérez de la Cruz, A

    1995-01-01

    Enteral nutrition in the home of the patient, has gained interest in recent years. In our health care area, we do not have a Unit of at Home Hospitalization, which has not prevented the implementation of this therapeutic modality in certain types of patients. 89 cases who have undergone enteral Nutrition in their home after the last hospital admission, were reviewed. According to the basic pathology, 41.6% (37 patients) correspond to neurological patients; 51.7% correspond to neoplasmic patients, and 6.7% are classified as miscellaneous. The average age is 64 years (18 months-92 years); the mean caloric ingestion is 1,520 Kcal/day (500-2,500), and the duration is a mean of 315 days (7-1,560). The complications observed through ambulatory visits of the patient and/or the family, accounted for a total of 36, of which 30 (83%) were digestive, and were corrected with the usual methods. In 8 cases (22%), it involved mechanical complications, and only 2 cases involved metabolic complications. Only 1 serious complication (massive bronchoaspiration) could have been avoided. The results indicate a good degree of acceptance, with similar results to those described by other authors, and with a low incidence of severe complications.

  2. Filamentous Influenza Virus Enters Cells via Macropinocytosis

    Science.gov (United States)

    Rossman, Jeremy S.; Leser, George P.

    2012-01-01

    Influenza virus is pleiomorphic, producing both spherical (100-nm-diameter) and filamentous (100-nm by 20-μm) virions. While the spherical virions are known to enter host cells through exploitation of clathrin-mediated endocytosis, the entry pathway for filamentous virions has not been determined, though the existence of an alternative, non-clathrin-, non-caveolin-mediated entry pathway for influenza virus has been known for many years. In this study, we confirm recent results showing that influenza virus utilizes macropinocytosis as an alternate entry pathway. Furthermore, we find that filamentous influenza viruses use macropinocytosis as the primary entry mechanism. Virions enter cells as intact filaments within macropinosomes and are trafficked to the acidic late-endosomal compartment. Low pH triggers a conformational change in the M2 ion channel protein, altering membrane curvature and leading to a fragmentation of the filamentous virions. This fragmentation may enable more-efficient fusion between the viral and endosomal membranes. PMID:22875971

  3. Ecocardiografia modo Doppler pulsado em gatos clinicamente sadios Pulsed wave Doppler echocardiography in clinically healthy cats

    Directory of Open Access Journals (Sweden)

    R.O. Carvalho

    2006-06-01

    Full Text Available Estudou-se o fluxo sangüíneo através das quatro valvas cardíacas em 30 gatos clinicamente sadios, com idade entre um e cinco anos e peso médio de 4,08kg, por meio da ecocardiografia modo Doppler pulsado. Foram medidas a velocidade máxima e a velocidade média dos fluxos, e realizou-se uma análise qualitativa dos seus perfis. Os animais foram sedados pela combinação de quetamina (12mg/kg e acepromazina (0,04mg/kg, aplicados por via intramuscular. Observou-se correlação positiva entre os parâmetros avaliados e a freqüência cardíaca, com exceção daqueles medidos no fluxo da valva aórtica. Não se observou correlação entre velocidades máxima e média e freqüência cardíaca e entre aquelas e peso corporal, e não houve diferença entre sexos.Pulsed wave Doppler echocardiography was used to study blood flow across the cardiac valves in 30 five-year-old cats (average body weight = 4.08kg. Animals were sedated using a combination of ketamin (12mg/kg, IM and acepromazin (0.04mg/kg, IM. Peak and mean velocities were determined, and blood flow patterns were recorded at the four cardiac valves. All variables, except those characterizing aortic valve flow, were positively correlated with heart rate. Blood flow variables were not correlated, however, with body weight; and there were no differences between males and females.

  4. Enteric parasitic infections among secondary school students in ...

    African Journals Online (AJOL)

    Enteric parasitic infections among secondary school students in Gusau, ... Age, gender, marital status, anaemia and type of toilet significantly affected the ... There was no case of mixed infection of enteric parasites observed in this study.

  5. Routes for early enteral nutrition after esophagectomy : A systematic review

    NARCIS (Netherlands)

    Weijs, Teus J|info:eu-repo/dai/nl/413993558; Berkelmans, Gijs H K; Nieuwenhuijzen, Grard A P; Ruurda, Jelle P|info:eu-repo/dai/nl/257561021; Hillegersberg, Richard V|info:eu-repo/dai/nl/110706242; Soeters, Peter B; Luyer, Misha D P

    BACKGROUND: Early enteral feeding following surgery can be given orally, via a jejunostomy or via a nasojejunal tube. However, the best feeding route following esophagectomy is unclear. OBJECTIVES: To determine the best route for enteral nutrition following esophagectomy regarding anastomotic

  6. Incidence of Diarrhea in Hospitalized Patients with Standard Enteral Formula

    National Research Council Canada - National Science Library

    Shabbu Ahmadi bonakdar; Mahdieh Pouryazdanpanah; Zahra Ganie Far; Saba Ghazanfari; Abdolreza Norouzy

    2014-01-01

    ...`s reports standard enteral formula is inducing diarrhea. In this study our purpose is to evaluate the incidence of diarrhea in hospitalized patients with standard Enteral Nutrition (EN) formula intake...

  7. Ultrasonographic abnormalities and inter-reader reliability in Danish patients with systemic lupus erythematosus - a comparison with clinical examination of wrist and metacarpophalangeal joints

    DEFF Research Database (Denmark)

    Dreyer, L; Jacobsen, Søren; Juul, L

    2015-01-01

    . METHODS: Thirty-three female SLE patients were twice examined with US by three trained examiners. Using B-mode and Doppler US, unilateral wrist and metacarpophalangeal (MCP) joints were examined for synovitis and erosions as well as signs of hand tenosynovitis using a GE Logiq 9 US machine with Doppler......%) and 0 (p = 0.06). In SLE patients, 18% had hand tenosynovitis and 6% bone erosions. Wrist synovitis was detected by US in 16 SLE patients (81%) with arthralgia compared with 17 patients without (18%) (p = 0.0005). Any US abnormalities were observed in 44% of 25 wrists without tenderness at clinical...... of synovitis, erosions and tenosynovitis indicating subclinical disease. Even SLE patients without clinical signs of joint inflammation demonstrated US abnormalities. Good to excellent inter-observer reliability was found in US evaluation of hands in patients with SLE....

  8. A prospective comparative study to assess the effect of maternal smoking at 37 weeks on Doppler flow velocity waveforms as well as foetal birth weight and placental weight.

    Science.gov (United States)

    Alptekin, Hüsnü; Işık, Hatice; Alptekin, Nazife; Kayhan, Fatih; Efe, Duran; Cengiz, Türkan; Gök, Emine

    2017-02-01

    Maternal smoking is known to have adverse effects on the foetus. This study aimed to evaluate the effects of maternal smoking during pregnancy on arterial blood flow velocities in the foetal-placental-maternal circulation, and the pathophysiological relationship with placental and foetal birth weight. A total of 148 singleton pregnancies in 59 smokers and 89 non-smoking controls were examined during the 37th week of gestation. Blood flow in the maternal uterine, foetal umbilical and middle cerebral arteries was analysed with Doppler ultrasonography. Statistically significant differences in Doppler waveforms were detected in the foetal umbilical artery (UmbA) (p  0.05). Both infant birthweight and placental weight were significantly decreased by maternal smoking (p< 0.001 for both). Maternal smoking during pregnancy did not affect either maternal uterine or foetal middle cerebral arterial blood flow, but caused abnormal blood flow in the foetal UmbA.

  9. Doppler Spectrum from Moving Scatterers in a Random Environment

    DEFF Research Database (Denmark)

    Andersen, Jørgen Bach; Nielsen, Jesper Ødum; Pedersen, Gert Frølund

    2009-01-01

    A random non-line-of-sight environment with stationary transmitter and receiver is considered. In such an environment movement of a scatterer will lead to perturbations of the otherwise static channel with a resulting Doppler spectrum. This is quite a general situation in outdoor environments...... with moving traffic or indoor situations with moving people. Here we study the latter situation in detail with experimental results from a large office environment. A general theory of Doppler spectra is developed. The impact of a scatterer depends on the angular distribution of scattered energy, and uniform...... as well as sharply peaked distributions are considered in the theory. The Doppler spectra are in all cases sharply peaked at zero frequency due to forward scattering, but the actually measured distribution depends on the degree and type of activity in the environment, as well as the spectrum estimation...

  10. Rotational Doppler Effect: A Probe for Molecular Orbitals Anisotropy.

    Science.gov (United States)

    Miao, Quan; Travnikova, Oksana; Gel'mukhanov, Faris; Kimberg, Victor; Sun, Yu-Ping; Thomas, T Darrah; Nicolas, Christophe; Patanen, Minna; Miron, Catalin

    2015-05-07

    The vibrationally resolved X-ray photoelectron spectra of X2Σg+(3σg−1) and B2Σu+(2σu−1) states of N2+ were recorded for different photon energies and orientations of the polarization vector. Clear dependencies of the spectral line widths on the X-ray polarization as well as on the symmetry of the final electronic states are observed. Contrary to the translational Doppler, the rotational Doppler broadening is sensitive to the photoelectron emission anisotropy. On the basis of theoretical modeling, we suggest that the different rotational Doppler broadenings observed for gerade and ungerade final states result from a Young's double-slit interference phenomenon.

  11. Theoretical analysis and experimental verification on optical rotational Doppler effect.

    Science.gov (United States)

    Zhou, Hailong; Fu, Dongzhi; Dong, Jianji; Zhang, Pei; Zhang, Xinliang

    2016-05-02

    We present a theoretical model to sufficiently investigate the optical rotational Doppler effect based on modal expansion method. We find that the frequency shift content is only determined by the surface of spinning object and the reduced Doppler shift is linear to the difference of mode index between input and output orbital angular momentum (OAM) light, and linear to the rotating speed of spinning object as well. An experiment is carried out to verify the theoretical model. We explicitly suggest that the spatial spiral phase distribution of spinning object determines the frequency content. The theoretical model makes us better understand the physical processes of rotational Doppler effect, and thus has many related application fields, such as detection of rotating bodies, imaging of surface and measurement of OAM light.

  12. Non-intrusive Shock Measurements Using Laser Doppler Vibrometers

    Science.gov (United States)

    Statham, Shannon M.; Kolaini, Ali R.

    2012-01-01

    Stud mount accelerometers are widely used by the aerospace industry to measure shock environments during hardware qualification. The commonly used contact-based sensors, however, interfere with the shock waves and distort the acquired signature, which is a concern not actively discussed in the community. To alleviate these interference issues, engineers at the Jet Propulsion Laboratory are investigating the use of non-intrusive sensors, specifically Laser Doppler Vibrometers, as alternatives to the stud mounted accelerometers. This paper will describe shock simulation tests completed at the Jet Propulsion Laboratory, compare the measurements from stud mounted accelerometers and Laser Doppler Vibrometers, and discuss the advantages and disadvantages of introducing Laser Doppler Vibrometers as alternative sensors for measuring shock environments.

  13. Manipulating the spin-dependent splitting by geometric Doppler effect.

    Science.gov (United States)

    Liu, Yachao; Ke, Yougang; Zhou, Junxiao; Luo, Hailu; Wen, Shuangchun

    2015-06-29

    We report the manipulation of spin-dependent splitting by geometric Doppler effect based on dielectric metasurfaces. The extrapolation of rotational Doppler effect from temporal to spatial coordinate gives the phase change when the local optical axes of dielectric metasurfaces are rotating in space. Therefore, the continuous variation of local optical axes in a certain direction will introduce a phase gradient in the same direction at the beam cross section. This is additive to the phase gradient appeared when breaking the rotational symmetry of linearly polarized cylindrical vector beams, which leads to the deflections of different spin components of light, i.e., photonic spin Hall effect. Hence, it is possible to manipulate the spin-dependent splitting by introducing the geometric Doppler effect. Theoretically and experimentally, we show that the magnitude and orientation of the spin-dependent splitting are both tunable when changing the spatial rotation rate of local optical axes and incident polarization.

  14. Intramuscular blood flow quantification with power doppler ultrasonography.

    Science.gov (United States)

    Dori, Amir; Abbasi, Hiba; Zaidman, Craig M

    2016-11-01

    Quantification of blood flow to muscle using ultrasound is limited to large vessels. Small vessel intramuscular blood flow cannot be quantified using ultrasound without specialized methods or intravenous contrast. We describe a technique using power Doppler to quantify postcontraction hyperemia in intramuscular vessels that can be used at the bedside. In 11 healthy subjects, postcontraction intramuscular blood flow in the forearm flexors and tibialis anterior muscles increased with stronger and repeated contractions. Intravascular blood flow measured by pulsed Doppler in the brachial artery similarly increased. Three patients with muscular dystrophies showed a negligible increase of postcontraction intramuscular blood flow. Intramuscular blood flow can be quantified using power Doppler ultrasonography; it increases following contraction and may be reduced in patients with muscular dystrophies. This quantitative, noninvasive technique can be applied at the bedside and may facilitate studies of disease impact on intramuscular blood flow. Muscle Nerve 54: 872-878, 2016. © 2016 Wiley Periodicals, Inc.

  15. Assessment of right ventricular systolic function by tissue Doppler echocardiography

    DEFF Research Database (Denmark)

    Kjærgaard, Jesper

    2012-01-01

    in individual patients [I]. Normal values of tissue Doppler based measurements of RV regional velocities, SR and strain exist, and apply to both sexes and in all age groups with the exception of slightly decreasing values in strain with increasing age. Increasing preload and afterload changes regional...... gained from other quantitative echocardiographic measures of LV and RV function and pressure [VI]. Changes in tissue Doppler based measures of RV systolic function can be used to monitor the effect of selective vasodilation by phosphodiestares-5 inhibition in hypoxic pulmonary hypertension and exercise...... in normal individuals. Phosphodiestares-5 inhibition by sildenafil may predominantly be effective during hypoxia in resting conditions, and may improve the blunted response in RV contractility seen with exercise in hypoxia [VII]. Reduced RV free wall deformation can be quantified by tissue Doppler...

  16. Princípios físicos do Doppler em ultra-sonografia Physical principles of Doppler ultrasonography

    Directory of Open Access Journals (Sweden)

    Cibele Figueira Carvalho

    2008-06-01

    Full Text Available A ultra-sonografia Doppler é um método relativamente recente dentro da rotina veterinária que fornece informações em tempo real da arquitetura vascular e dos aspectos hemodinâmicos dos vasos sanguíneos examinados em diversos órgãos vitais. Pode determinar a presença, a direção e o tipo de fluxo sanguíneo. Esta revisão de literatura compila as informações sobre os princípios físicos da ultra-sonografia Doppler. A ampliação do conhecimento desta tecnologia possibilita a melhor compreensão das aplicações e limitações deste método diagnóstico, que tem se tornado rotina na medicina veterinária de pequenos animais.Doppler ultrasonography is a relatively new diagnostic tool in veterinary medicine that provides real time details about vascular architecture and hemodynamic aspects of examinated blood vessels in several internal organs. Doppler can identify the presence, direction and type of blood flow. This literature review provides information about the physical principles of Doppler ultrasonography. The enlargement of expertise about this technology lead to a better comprehension of its use and limitations as a diagnostic technique, which already becomes usual in veterinary medicine of small animals.

  17. UltraFast Doppler ultrasonography for hepatic vessels of liver recipients: preliminary experiences

    Science.gov (United States)

    2015-01-01

    Purpose: The purpose of this study was to investigate the value of UltraFast Doppler ultrasonography (US) for evaluating hepatic vessels in liver recipients. Methods: Thirty-nine liver Doppler US sessions were conducted in 20 liver recipients. Each session consisted of UltraFast and conventional liver Doppler US in a random order. We compared the velocities and phasicities of the hepatic vessels, duration of each Doppler study, occurrence of technical failures, and differences in clinical decisions. Results: The velocities and resistive index values of hepatic vessels showed a strong positive correlation between the two Doppler studies (mean R=0.806; range, 0.710 to 0.924). The phasicities of the hepatic vessels were the same in both Doppler US exams. With respect to the duration of the Doppler US exam, there was no significant difference between the UltraFast (251±99 seconds) and conventional (231±117 seconds) Doppler studies (P=0.306). In five poor breath-holders, in whom the duration of conventional Doppler US was longer, UltraFast Doppler US (272±157 seconds) required a shorter time than conventional Doppler US (381±133 seconds; P=0.005). There was no difference between the two techniques with respect to technical failures and clinical decisions. Conclusion: UltraFast Doppler US is clinically equivalent to conventional Doppler US with advantages for poor breath-holders during the post-liver transplantation work-up. PMID:25409662

  18. UltraFast Doppler ultrasonography for hepatic vessels of liver recipients: preliminary experiences

    Energy Technology Data Exchange (ETDEWEB)

    Hur, Bo Yun; Lee, Jae Young; Chu, A Jung; Kim, Se Hyung; Han, Joon Koo; Choi, Byung Ihn [Seoul National University Hospital, Seoul (Korea, Republic of)

    2015-01-15

    The purpose of this study was to investigate the value of UltraFast Doppler ultrasonography (US) for evaluating hepatic vessels in liver recipients. Thirty-nine liver Doppler US sessions were conducted in 20 liver recipients. Each session consisted of UltraFast and conventional liver Doppler US in a random order. We compared the velocities and phasicities of the hepatic vessels, duration of each Doppler study, occurrence of technical failures, and differences in clinical decisions. The velocities and resistive index values of hepatic vessels showed a strong positive correlation between the two Doppler studies (mean R=0.806; range, 0.710 to 0.924). The phasicities of the hepatic vessels were the same in both Doppler US exams. With respect to the duration of the Doppler US exam, there was no significant difference between the UltraFast (251±99 seconds) and conventional (231±117 seconds) Doppler studies (P=0.306). In five poor breath-holders, in whom the duration of conventional Doppler US was longer, UltraFast Doppler US (272±157 seconds) required a shorter time than conventional Doppler US (381±133 seconds; P=0.005). There was no difference between the two techniques with respect to technical failures and clinical decisions. UltraFast Doppler US is clinically equivalent to conventional Doppler US with advantages for poor breath-holders during the post-liver transplantation work-up.

  19. UltraFast Doppler ultrasonography for hepatic vessels of liver recipients: preliminary experiences

    Directory of Open Access Journals (Sweden)

    Bo Yun Hur

    2015-01-01

    Full Text Available Purpose: The purpose of this study was to investigate the value of UltraFast Doppler ultrasonography (US for evaluating hepatic vessels in liver recipients. Methods: Thirty-nine liver Doppler US sessions were conducted in 20 liver recipients. Each session consisted of UltraFast and conventional liver Doppler US in a random order. We compared the velocities and phasicities of the hepatic vessels, duration of each Doppler study, occurrence of technical failures, and differences in clinical decisions. Results: The velocities and resistive index values of hepatic vessels showed a strong positive correlation between the two Doppler studies (mean R=0.806; range, 0.710 to 0.924. The phasicities of the hepatic vessels were the same in both Doppler US exams. With respect to the duration of the Doppler US exam, there was no significant difference between the UltraFast (251±99 seconds and conventional (231±117 seconds Doppler studies (P=0.306. In five poor breath-holders, in whom the duration of conventional Doppler US was longer, UltraFast Doppler US (272±157 seconds required a shorter time than conventional Doppler US (381±133 seconds; P=0.005. There was no difference between the two techniques with respect to technical failures and clinical decisions. Conclusion: UltraFast Doppler US is clinically equivalent to conventional Doppler US with advantages for poor breath-holders during the post-liver transplantation work-up.

  20. 9 CFR 113.204 - Mink Enteritis Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Mink Enteritis Vaccine, Killed Virus..., DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.204 Mink Enteritis Vaccine, Killed Virus. Mink Enteritis Vaccine...

  1. Early enteral nutrition compared to outcome in critically ill trauma ...

    African Journals Online (AJOL)

    Objectives: The benefit of an early enteral nutrition start in critical ill patients is widely accepted. However, limited published data focus on trauma patients. This study aimed to investigate the effect of early enteral nutrition initiation on length of stay and mortality in an intensive care unit (ICU), as well as explore if enteral ...

  2. Diagnostic value of appendicular Doppler ultrasonography in acute appendicitis.

    Science.gov (United States)

    Uzunosmanoğlu, Hüseyin; Çevik, Yunsur; Çorbacıoğlu, Şeref Kerem; Akıncı, Emine; Buluş, Hakan; Ağladıoğlu, Kadir

    2017-05-01

    Acute appendicitis is one of the most common causes of acute abdominal pain prompting emergency department (ED) visits. It is critical for the physicians to promptly and accurately diagnose acute appendicitis. The present study aimed to evaluate the diagnostic efficacy of Doppler ultrasonography (USG) in patients with acute appendicitis and compare this new method with other commonly used radio-diagnostic tools. All patients who were diagnosed with acute appendicitis at the Kecioren Training and Research Hospital ED and later underwent appendectomy between October 2012 and April 2013 were included in the study. Approval from the ethics committee was obtained for this prospective study. The patients' demographic information, physical examination findings, vital signs, Alvarado scores, and laboratory and radiological exam results were recorded. A total of 60 patients were enrolled in the study. In 46 of the 60 patients, diagnosis of acute appendicitis was confirmed by histopathology results, whereas 14 patients, diagnoses was not confirmed by lab tests. Doppler USG could detect 43 of the 46 patients as true positives, and it detected 2 of the 14 patients with negative lab results as false positives. For diagnosis of acute appendicitis, sensitivity of appendicular Doppler USG was 93%, specificity was 85%, accuracy was 91%, positive likelihood ratio was 6.5, and negative likelihood ratio was 0.08. Doppler imaging can offer a high level of diagnostic success in patients with acute appendicitis. Appendicular Doppler USG offers a rapid and easy application without the need to expose patients to contrast medium and is superior to both USG and computed tomography. Therefore, we recommend the use of appendicular Doppler imaging as the primary radiological exam in diagnosing acute appendicitis.

  3. Study of 2 years follow-up of referral patients with abnormal Pap smear.

    Science.gov (United States)

    Behnamfar, Fariba; Zafarbakhsh, Azam; Allameh, Taj-Alsadat

    2015-12-01

    Abnormal Pap smear consists of premalignant or malignant cervical lesions. Many of premalignant cervical lesions will never progress to invasive malignancy, or even may regress over the time. Thus, there is always a risk of overtreatment of patients with an abnormal Pap smear. A long-term follow-up of these patients can reveal final events associated with each subtype of abnormal Pap smear, and, therefore, help us to prevent unnecessary interventions. The aim of our study was to present 2 years follow-up of referral patients with abnormal Pap smear. A total of 334 consecutive women aged more than 16 who were referred with an abnormal Pap smear were entered into the study. Patients were followed with biannual Pap smear and annual colposcopy and biopsy for 2 years. At baseline, the majority of patients with abnormal Pap smear were normal on colposcopy and biopsy (68% and 86%, respectively). Six months after first abnormal Pap smear majority of patients in each group showed a significant regress to normal or less invasive lesion (P Pap smear, whereas 313 (94%) had at least one stage improvement. Only nine (3%) patients had deteriorated Pap smear after 6 months. All 308 patients who underwent colposcopy and biopsy had normal Pap smear 24 months after the first abnormal Pap smear. Pap smear is associated with a high rate of false-positive results. In addition, the majority of low-grade cervical lesions can spontaneously regress. A long-term follow-up of a patient with abnormal Pap smear can help us to avoid needless interventions.

  4. Imaging doppler lidar for wind turbine wake profiling

    Science.gov (United States)

    Bossert, David J.

    2015-11-19

    An imaging Doppler lidar (IDL) enables the measurement of the velocity distribution of a large volume, in parallel, and at high spatial resolution in the wake of a wind turbine. Because the IDL is non-scanning, it can be orders of magnitude faster than conventional coherent lidar approaches. Scattering can be obtained from naturally occurring aerosol particles. Furthermore, the wind velocity can be measured directly from Doppler shifts of the laser light, so the measurement can be accomplished at large standoff and at wide fields-of-view.

  5. Ultrasonography and color Doppler in juvenile idiopathic arthritis

    DEFF Research Database (Denmark)

    Laurell, Louise; Court-Payen, Michel; Nielsen, Susan

    2011-01-01

    Background The ankle region is frequently involved in juvenile idiopathic arthritis (JIA) but difficult to examine clinically due to its anatomical complexity. The aim of the study was to evaluate the role of ultrasonography (US) of the ankle and midfoot (ankle region) in JIA. Doppler-US detected...... hypertrophy, effusion) and by color Doppler (synovial hyperemia) before and 4 weeks after US-guided steroid injection. Results US detected 121 compartments with active disease (joints, tendon sheaths and 1 ganglion cyst). Multiple compartments were involved in 80% of the ankle regions. The talo-crural joint...

  6. Use of Transcranial Doppler in Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    Viski Sandor

    2017-07-01

    Full Text Available Use of transcranial Doppler has undergone much development since its introduction in 1982, making the technique suitable for general use in intensive care units. The main application in intensive care units is to assess intracranial pressure, confirm the lack of cerebral circulation in brain death, detect vasospasm in subarachnoid haemorrhage, and monitor the blood flow parameters during thrombolysis and carotid endarterectomy, as well as measuring stenosis of the main intracranial arteries in sickle cell disease in children. This review summarises the use of transcranial Doppler in intensive care units.

  7. Multigroup Free-atom Doppler-broadening Approximation. Theory

    Energy Technology Data Exchange (ETDEWEB)

    Gray, Mark Girard [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-11-06

    Multigroup cross sections at a one target temperature can be Doppler-broadened to multigroup cross sections at a higher target temperature by matrix multiplication if the group structure suf- ficiently resolves the original temperature continuous energy cross section. Matrix elements are the higher temperature group weighted averages of the integral over the lower temperature group boundaries of the free-atom Doppler-broadening kernel. The results match theory for constant and 1/v multigroup cross sections at 618 lanl group structure resolution.

  8. System-on-chip based Doppler radar occupancy sensor.

    Science.gov (United States)

    Yavari, Ehsan; Song, Chenyan; Lubecke, Victor; Boric-Lubecke, Olga

    2011-01-01

    System-on-Chip (SoC) based Doppler radar occupancy sensor is developed through non contact detection of respiratory signals. The radio was developed using off the shelf low power RF CC2530 SoC chip by Texas Instruments. In order to save power, the transmitter sends signal intermittently at 2.405 GHz. Reflected pulses are demodulated, and the baseband signals are processed to recover periodic motion. The system was tested both with mechanical target and a human subject. In both cases Doppler radar detected periodic motion closely matched the actual motion, and it has been shown that an SoC based system can be used for subject detection.

  9. Accommodations assessment: Spaceborne Doppler lidar wind measuring system

    Science.gov (United States)

    1981-01-01

    An accommodations analysis performed by the MSFC Preliminary Design Office for a spaceborne Doppler lidar wind measuring system is summarized. A dedicated, free-flying spacecraft design concept is described. Mass and beginning-of-life power requirements are estimated at 2260 kg and 6.0 - 8.5 kW respectively, to support a pulsed, CO2, Doppler lidar having a pulse energy of 10 J, pulse rate of 8 Hz, and efficiency of approximately 5%. Under the assumptions of the analysis, such a system would provide wind measurements on a global scale, with accuracies of a few meters per second.

  10. Spectral Doppler ultrasound of peripheral arteries: a pictorial review.

    Science.gov (United States)

    Nuffer, Zachary; Rupasov, Andrey; Bekal, Neel; Murtha, Jacqueline; Bhatt, Shweta

    This article reviews the pathophysiology and sonographic findings of peripheral arterial lesions, with emphasis on the spectral Doppler waveforms encountered in each. It discusses the characteristic features of the Doppler spectra in obstructive conditions, including thromboembolism, atherosclerotic disease, bypass graft occlusion, dissection, trauma, and compartment syndrome, as well as non-obstructive conditions, including hyperemia, pseudoaneurysm, and arteriovenous fistula. Familiarity with the commonly-encountered spectral waveforms in the setting of these lesions is necessary for timely and accurate diagnosis and treatment. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Stretched-exponential Doppler spectra in underwater acoustic communication channels.

    Science.gov (United States)

    van Walree, P A; Jenserud, T; Otnes, R

    2010-11-01

    The theory of underwater sound interacting with the sea surface predicts a Gaussian-spread frequency spectrum in the case of a large Rayleigh parameter. However, recent channel soundings reveal more sharply peaked spectra with heavier tails. The measured Doppler spread increases with the frequency and differs between multipath arrivals. The overall Doppler spectrum of a broadband waveform is the sum of the spectra of all constituent paths and frequencies, and is phenomenologically described by a stretched or compressed exponential. The stretched exponential also fits well to the broadband spectrum of a single propagation path, and narrowband spectra summed over all paths.

  12. Special theory of relativity through the Doppler effect

    Energy Technology Data Exchange (ETDEWEB)

    Moriconi, M [Departamento de Fisica, Universidade Federal Fluminense, Av. Litoranea s/n, Boa Viagem-CEP 24210-340, Niteroi, Rio de Janeiro (Brazil)

    2006-11-01

    We present the special theory of relativity taking the Doppler effect as the starting point, and derive several of its main effects, such as time dilation, length contraction, addition of velocities and the mass-energy relation, and assuming energy and momentum conservation, we discuss how to introduce the 4-momentum in a natural way. We also use the Doppler effect to explain the 'twin paradox', and its version on a cylinder. As a by-product we discuss Bell's spaceship paradox, and the Lorentz transformation for arbitrary velocities in one dimension.

  13. Uterine artery Doppler in high-risk pregnancies at 23-24 gestational weeks is of value in predicting adverse outcome of pregnancy and selecting cases for more intense surveillance.

    Science.gov (United States)

    Li, Na; Ghosh, Gisela; Gudmundsson, Saemundur

    2014-12-01

    To assess the role of the placental arterial Doppler examination at 23-24 gestational weeks for predicting adverse perinatal outcome in high-risk pregnancies. Retrospective register study. Skåne University Hospital in Malmö. Six hundred and forty-five women with high-risk pregnancies, without fetal malformations or chromosomal abnormalities. Placental (uterine and umbilical artery) Doppler ultrasound examination at 23-24 gestational weeks. Adverse perinatal outcomes including preeclampsia, small-for-gestational age newborns (smaller than 3rd percentile or smaller than the 10th percentile), preterm delivery (high-risk group but abnormal umbilical artery Doppler indices were only seen in 3.7%. Adverse perinatal outcome increased significantly with increasing placental vascular impedance (p pregnancies at risk of adverse outcome and in selecting cases for more intense surveillance. A surveillance plan is proposed based on Doppler screening at 23-24 weeks of gestation. © 2014 Nordic Federation of Societies of Obstetrics and Gynecology.

  14. Determinant factors of the viscosity of enteral formulas: basic analysis of thickened enteral formulas.

    Science.gov (United States)

    Wakita, Maki; Masui, Hironori; Ichimaru, Satomi; Amagai, Teruyoshi

    2012-02-01

    Thickened enteral formula (TEF), which is made by adding thickener to enteral formula, has been used mainly in Japan to reduce the incidence of clinical complications associated with enteral nutrition. However, the optimal viscosity of TEF needed to achieve a high efficiency is different for each medical complication and for individual patients. The viscosity of TEF, which consists of enteral formula and thickener, was determined by 5 factors: (1) formula energy density, (2) formula temperature, (3) stirring speed, (4) stirring time, and (5) time elapsed since preparation. Then, the changing index (CI) was calculated for each of the 5 factors to determine which exerts the most influence on TEF viscosities. The most influential factor (CI ≥-50%) for the decrease in TEF viscosity was formula energy density. In contrast, the most influential factors (CI ≥50%) for the increase in TEF viscosity were stirring time and time elapsed since preparation. The results of this study indicate that formula energy density, stirring time, and time elapsed since preparation are the most influential factors to consider during manipulation of TEF viscosity.

  15. Acrodermatitis enteropathica during adequate enteral nutrition.

    Science.gov (United States)

    Changela, Avani; Javaiya, Hemangkumar; Changela, Kinesh; Davanos, Evangelia; Rickenbach, Kiersten

    2012-03-01

    Acrodermatitis enteropathica is a rare skin disorder of zinc deficiency. This case report describes a 91-year-old female nursing home resident who presented with a skin eruption resembling acrodermatitis enteropathica while receiving adequate enteral nutrition (EN) via a percutaneous gastrostomy tube. A low zinc level of 36 mcg/dL confirmed zinc deficiency, and treatment with oral zinc sulfate 220 mg 3 times a day resulted in rapid resolution of the skin lesions. This case supports the notion of close monitoring of patients on long-term EN for clinical manifestations of zinc deficiency, especially in the presence of an unexplained skin rash. Although micronutrient deficiencies are more prevalent in underdeveloped countries and with patients receiving parenteral nutrition, these deficiencies should be kept in mind for patients in developed countries as well as patients receiving EN.

  16. Pathogenesis of Salmonella-induced enteritis

    Directory of Open Access Journals (Sweden)

    R.L. Santos

    2003-01-01

    Full Text Available Infections with Salmonella serotypes are a major cause of food-borne diseases worldwide. Animal models other than the mouse have been employed for the study of nontyphoidal Salmonella infections because the murine model is not suitable for the study of Salmonella-induced diarrhea. The microbe has developed mechanisms to exploit the host cell machinery to its own purpose. Bacterial proteins delivered directly into the host cell cytosol cause cytoskeletal changes and interfere with host cell signaling pathways, which ultimately enhance disease manifestation. Recently, marked advances have been made in our understanding of the molecular interactions between Salmonella serotypes and their hosts. Here, we discuss the molecular basis of the pathogenesis of Salmonella-induced enteritis.

  17. [SHORT BOWEL SYNDROME AND NUTRITIONAL ENTERAL].

    Science.gov (United States)

    Ariadel Cobo, Diana; Pereira Cunill, José Luis; Socas Macías, María; Serrano Aguayo, Pilar; Gómez Liébana, Eulalia; Morales Conde, Salvador; García Luna, Pedro Pablo

    2015-12-01

    The particularity of this case is the nutritional management that has managed to avoid the use of prolonged parenteral nutrition and possible complications by placing jejunal tube at the distal end in patients with short bowel. It is a 34-year-old colecistectomizado complicated with postoperative peritonitis and dehiscence; two years he studied with small bowel obstruction, he was made de-volvulus and was complicated with two leak at different times after the second escape took place jejunostomy side double barreled shotgun level dehiscence, presented high debits by afferent loop of the terminal jejunostomy; during admission, polyurethane probe enteral feeding was inserted by the efferent loop jejunostomy. He received jejunal tube feeding laundry in the efferent loop terminal with decreased weight gain and subsequent reconstruction of intestinal transit debit proximal jejunostomy. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  18. Optimal Time to Enter a Retirement Village

    Directory of Open Access Journals (Sweden)

    Jinhui Zhang

    2017-03-01

    Full Text Available We consider the financial planning problem of a retiree wishing to enter a retirement village at a future uncertain date. The date of entry is determined by the retiree’s utility and bequest maximisation problem within the context of uncertain future health states. In addition, the retiree must choose optimal consumption, investment, bequest and purchase of insurance products prior to their full annuitisation on entry to the retirement village. A hyperbolic absolute risk-aversion (HARA utility function is used to allow necessary consumption for basic living and medical costs. The retirement village will typically require an initial deposit upon entry. This threshold wealth requirement leads to exercising the replication of an American put option at the uncertain stopping time. From our numerical results, active insurance and annuity markets are shown to be a critical aspect in retirement planning.

  19. Reactive Arthritis Caused by Yersinia enterocolitica Enteritis.

    Science.gov (United States)

    Honda, Kazuya; Iwanaga, Nozomi; Izumi, Yasumori; Tsuji, Yoshika; Kawahara, Chieko; Michitsuji, Toru; Higashi, Shuntaro; Kawakami, Atsushi; Migita, Kiyoshi

    2017-01-01

    We report a case of reactive arthritis (ReA) triggered by Yersinia enterocolitica enteritis. A 24-year-old Japanese man developed polyarthritis in the lower limbs. Two weeks prior to these symptoms, he noted diarrhea, right lower abdominal pain and a fever. Y. enterocolitica was not isolated from a stool culture; however, he was diagnosed with ReA based on the colonoscopic findings of a high anti-Y. enterocolitica antibody titer and HLA-B27 antigen positivity. Following treatment with methotrexate and steroids, his arthritis improved. This is the first reported Japanese case of ReA in the English literature after a gastrointestinal infection caused by Y. enterocolitica.

  20. Grey-scale and colour Doppler sonography in the evaluation of children with suspected bowel inflammation: correlation with colonoscopy and histological findings

    Energy Technology Data Exchange (ETDEWEB)

    Epifanio, M. [Servico de Gastroenterologia Pediatrica do Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre (Brazil)], E-mail: mepifanio@hotmail.com; Baldisserotto, M. [Servico de Radiologia do Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre (Brazil); Spolidoro, J.V. [Servico de Gastroenterologia Pediatrica do Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre (Brazil); Gaiger, A. [Laboratorio Patologistas Reunidos, Porto Alegre (Brazil)

    2008-09-15

    Aim: To evaluate the correlation of grey-scale and colour Doppler sonography with colonoscopy and histology to detect bowel inflammation in children. Material and methods: The records of 72 patients with suspected bowel inflammation were reviewed retrospectively. Patients were included in the study if sonography had been performed up to 30 days before colonoscopy. Grey-scale and colour Doppler sonography were used to evaluate bowel wall thickness and vascularity for the detection of distal bowel inflammation. Findings were correlated with colonoscopy and histological findings. The sensitivity and specificity of sonographic wall thickness to detect inflammation was determined. Spearman's coefficient (rs) was used to determine the correlation of Doppler findings with colonoscopy/histology. Results: Sonograms of 372 bowel segments were evaluated and results were correlated with colonoscopy and histological findings of 352 segments. The sensitivity and specificity of sonographic bowel thickness to detect inflammation in the terminal ileum and the right colon were high; in the other segments, specificity was high but sensitivity was low. The correlation of Doppler sonography with colonoscopy and histology to detect inflammation in the terminal ileum was strong (rs: 0.84; p < 0.001) and in the other segments, weak to moderate; when the interval between examinations was shorter than 10 days, the correlation was stronger in all segments. Of nine patients with abnormal small bowel sonograms but normal colonoscopies, three had Crohn's disease. Conclusion: Sensitivity and specificity of grey-scale sonography to detect inflammation in the terminal ileum and the right colon were high, and the correlation of Doppler with colonoscopy and histology was very strong in the same segments.

  1. Assessment of maternal Doppler parameters of ophthalmic artery in fetuses with growth restriction in the third trimester of pregnancy: A case-control study.

    Science.gov (United States)

    Melo, Nayana Alves De Brito; Araujo Júnior, Edward; Helfer, Talita Micheletti; Caetano, Ana Carolina Rabachini; Zamarian, Ana Cristina Perez; Moron, Antonio Fernandes; Diniz, Angélica Lemos Debs; Nardozza, Luciano Marcondes Machado

    2015-09-01

    The aim of this study was to assess the Doppler parameters of the ophthalmic artery of pregnant women carrying fetuses with growth restriction (FGR) compared with normal fetuses. A prospective cross-sectional study was conducted with 120 pregnant women (60 FGR and 60 normal fetuses) between 32 and 40 weeks of gestation. FGR diagnosis was based on an estimated fetal weight below the 10th percentile of the Hadlock curve. Ophthalmic artery Doppler images were obtained with a linear transducer, with color Doppler examination of the region medial to the optic nerve. The following indices were obtained: pulsatility index, resistance index, peak systolic velocity, second peak velocity (P2), end diastolic velocity, and P2 / peak systolic velocity ratio. The Mann-Whitney U-test and Student's t-test were used to compare the groups with regard to quantitative variables, and the χ(2) -test was used for categorical variables. Pulsatility index and resistance index were significantly lower in pregnant women with FGR than in those with normal fetuses, with P < 0.001 in both indices. P2 and end diastolic velocity were significantly higher in pregnant women with FGR than in those with normal fetuses (P = 0.002 and P = 0.004, respectively). The P2 / peak systolic velocity ratio was significantly higher in the FGR group than in the control group (P < 0.001). In FGR subgroups, with (17 fetuses) and without (43 fetuses) uterine artery Doppler abnormalities, no significant changes were observed between the groups. In the third trimester of pregnancy, we observed significant differences in the ophthalmic artery Doppler parameters of pregnant women with FGR compared with those with normal fetuses. © 2015 Japan Society of Obstetrics and Gynecology.

  2. Preparation and evaluation of duloxetine hydrochloride enteric-coated pellets with different enteric polymers

    Directory of Open Access Journals (Sweden)

    Chen Kuang

    2017-05-01

    Full Text Available The main purpose of the present study was to prepare duloxetine hydrochloride (DXH enteric-coated pellets using different enteric polymers. Three layers (drug-loaded layer, barrier layer, and enteric-coated layer were applied to the inert core pellets, successively. The optimal formulation was manufactured by employing suspension layering method in fluidized bed processor (FBP with varieties of enteric polymers like Aqoat® AS-LF, Eudragit® L30D55 and HPMCP-HP55. The prepared pellets were measured for physical characterization and the in vitro dissolution profile. Scanning electron microscopy (SEM was conducted to observe the morphology of pellets, and different kinetic models were applied to analyze the release mechanism of Cymbalta® and home-made pellets. The coating weight gain of enteric-coated layer containing Eudragit® L30D55, Aqoat® AS-LF and HP-55 were determined to be 35%, 26% and 24%, respectively. The similarity factors (f2 of self-made capsules with above polymers and commercially available capsules (Cymbalta® were above 50 in the dissolution medium of pH 6.8 phosphate buffer solution (PBS. SEM figures showed the smooth surfaces of self-prepared pellets using Eudragit® L30D55 and Aqoat® AS-LF, whereas rough surface was found in the HP-55 pellets at day 0, and an impurity was appearing in the condition of 40 °C/75% relative humidity for 1 month. In conclusion, the pellets prepared by utilizing Eudragit® L30D55 and Aqoat® AS-LF were the optimal preparations based on the dissolution profile and stability.

  3. Acoustic doppler methods for remote measurements of ocean flows - a review

    Digital Repository Service at National Institute of Oceanography (India)

    Joseph, A.

    The evolution of acoustic doppler methods for remote measurements of ocean flows has been briefly reviewed in historical perspective. Both Eulerian and profiling methods have been discussed. Although the first acoustic Doppler current meter has been...

  4. Effect of preload alternations on a new Doppler echocardiographic index of combined systolic and diastolic performance

    DEFF Research Database (Denmark)

    Møller, J E; Poulsen, S H; Egstrup, K

    1999-01-01

    The objective of the study was to assess the effect of preload alternations on a nongeometric Doppler index of combined systolic and diastolic myocardial performance (MPI). Doppler echocardiography was performed during Valsalva maneuver, passive leg lifting, and after sublingual administration...

  5. GPM Ground Validation NASA S-Band Dual Polarimetric (NPOL) Doppler Radar OLYMPEX V2

    Data.gov (United States)

    National Aeronautics and Space Administration — The GPM Ground Validation NASA S-Band Dual Polarimetric (NPOL) Doppler Radar OLYMPEX V2 dataset consists of rain rate, reflectivity, Doppler velocity, and other...

  6. Chromosomal abnormalities in child psychiatric patients.

    OpenAIRE

    Hong, K. E.; Kim, J. H.; Moon, S. Y.; Oh, S. K.

    1999-01-01

    To determine the frequency of chromosomal abnormalities in a child psychiatric population, and to evaluate possible associations between types of abnormalities and patient's clinical characteristics, cytogenetic examination was performed on 604 patients. Demographic data, reasons for karyotyping, clinical signs, and other patient characteristics were assessed and correlated with the results from karyotyping. Chromosomal abnormalities were found in 69 patients (11.3%); these were structural in...

  7. Semen abnormalities with SSRI antidepressants.

    Science.gov (United States)

    2015-01-01

    Despite decades of widespread use, the adverse effect profile of "selective" serotonin reuptake inhibitor (SSRI) antidepressants has still not been fully elucidated. Studies in male animals have shown delayed sexual development and reduced fertility. Three prospective cohort studies conducted in over one hundred patients exposed to an SSRI for periods ranging from 5 weeks to 24 months found altered semen param-eters after as little as 3 months of exposure: reduced sperm concentration, reduced sperm motility, a higher percentage of abnormal spermatozoa, and increased levels of sperm DNA fragmentation. One clinical trial showed growth retardation in children considered depressed who were exposed to SSRls. SSRls may have endocrine disrupting properties. Dapoxetine is a short-acting serotonin reuptake inhibitor that is chemically related to fluoxetine and marketed in the European Union for men complaining of premature ejaculation. But the corresponding European summary of product characteristics does not mention any effects on fertility. In practice, based on the data available as of mid-2014, the effects of SSRI exposure on male fertility are unclear. However, it is a risk that should be taken into account and pointed out to male patients who would like to father a child or who are experiencing fertility problems.

  8. [Cognitive abnormalities and cannabis use].

    Science.gov (United States)

    Solowij, Nadia; Pesa, Nicole

    2010-05-01

    Evidence that cannabis use impairs cognitive function in humans has been accumulating in recent decades. The purpose of this overview is to update knowledge in this area with new findings from the most recent literature. Literature searches were conducted using the Web of Science database up to February 2010. The terms searched were: "cannabi*" or "marijuana", and "cogniti*" or "memory" or "attention" or "executive function", and human studies were reviewed preferentially over the animal literature. Cannabis use impairs memory, attention, inhibitory control, executive functions and decision making, both during the period of acute intoxication and beyond, persisting for hours, days, weeks or more after the last use of cannabis. Pharmacological challenge studies in humans are elucidating the nature and neural substrates of cognitive changes associated with various cannabinoids. Long-term or heavy cannabis use appears to result in longer-lasting cognitive abnormalities and possibly structural brain alterations. Greater adverse cognitive effects are associated with cannabis use commencing in early adolescence. The endogenous cannabinoid system is involved in regulatory neural mechanisms that modulate processes underlying a range of cognitive functions that are impaired by cannabis. Deficits in human users most likely therefore reflect neuroadaptations and altered functioning of the endogenous cannabinoid system.

  9. Red cell membrane transport abnormalities.

    Science.gov (United States)

    Bruce, Lesley J

    2008-05-01

    The present review describes the red cell transport abnormalities of proteins of the band 3 macrocomplex. The macrocomplex is involved in red cell gas exchange and recent findings have furthered our understanding of this process. Study of a novel band 3 hereditary spherocytosis variant suggests that expression of mutant band 3 protein can be rescued by wild-type band 3. Other studies show that some mutant band 3 protein can mediate a cation conductance. Recent work suggests both Rh-associated glycoprotein and aquaporin act as gas channels confirming the integrated function of the macrocomplex and the importance of its role in red cell gas transport. The most recent studies on band 3-induced hereditary spherocytosis are reviewed and an explanation for the mild phenotype of heterozygous hereditary spherocytosis is discussed. A number of red cell conditions (hereditary stomatocytosis, south-east Asian ovalocytosis, distal renal tubular acidosis, Rhnull), associated with both stomatocytosis and a cation leak, are described. The evidence that Rh-associated glycoprotein forms a gas channel that transports CO2 and/or NH3 is reviewed and discussed, together with recent studies that show that aquaporin 1 transports both CO2 and O2.

  10. The modeling of frequency Doppler shift in multibeam weakly non-stationary radio channels

    Science.gov (United States)

    Penzin, M. S.; Ilyin, N. V.

    2015-11-01

    Under measurement of Doppler shift for signal frequency one define the characteristic average on time or Doppler spectrum. The use of impulses coherent sequence allows to measure Doppler shift of frequency taking into account its small variations caused by non-stationarity of the ionospheric radio channel. In the report we consider the changes of frequency Doppler shift for each beam depending on time under modeling the propagation of impulses coherent sequence through weakly non-stationary ionospheric radio channel.

  11. Doppler Compensation for Airborne Non-Side-Looking Phased-Array Radar

    Science.gov (United States)

    2015-09-01

    UNCLASSIFIED UNCLASSIFIED Doppler Compensation for Airborne Non-Side- Looking Phased-Array Radar Yunhan Dong National Security...side-looking modes, including the forward-looking mode. A simple Doppler compensation scheme is described, so that the Doppler frequency of mainlobe...clutter is shifted to zero and becomes range invariant, like the clutter data collected from the side-looking geometry. After Doppler compensation

  12. Management of syndromic diarrhea/tricho-hepato-enteric syndrome: A review of the literature.

    Science.gov (United States)

    Fabre, Alexandre; Bourgeois, Patrice; Coste, Marie-Edith; Roman, Céline; Barlogis, Vincent; Badens, Catherine

    2017-08-01

    Syndromic diarrhea/tricho-hepato-enteric syndrome (SD/THE) is a rare disease linked to the loss of function of either TTC37 or SKIV2L, two components of the SKI complex. It is characterized by a combination of 9 signs (intractable diarrhea, hair abnormalities, facial dysmorphism, immune abnormalities, IUGR/SGA, liver abnormalities, skin abnormalities, congenital heart defect and platelet abnormalities). We present a comprehensive review of the management of SD/THE and tested therapeutic regimens. A review of the literature was conducted in May 2017: 29 articles and 2 abstracts were included describing a total of 80 patients, of which 40 presented with mutations of TTC37, 14 of SKIV2L. Parenteral nutrition was used in the management of 83% of the patients and weaned in 44% (mean duration of 14.97 months). Immunoglobulins were used in 33 patients, but data on efficacy was reported for 6 patients with a diminution of infection (n = 3) or diarrhea reduction (n = 2). Antibiotics (n = 11) provided no efficacy. Steroids (n = 17) and immunosuppressant drugs (n = 13) were used with little efficacy and mostly in patients with IBD-like SD/THE. Hematopoietic stem cell transplantation (HSCT) was performed in 4 patients: 2 died, for one it corrected the immune defects but not the other features and for the last one, it provided only a partial improvement. Finally, no specific diet was effective except for some contradictory reports for elemental formula. In conclusion, the management of SD/THE mainly involves parenteral nutrition and immunoglobulin supplementation. Antibiotics, steroids, immunosuppressants, and HSCT are not recommended as principle treatments since there is no evidence of efficacy.

  13. The Next Generation of Airborne Polarimetric Doppler Weather Radar: NCAR/EOL Airborne Phased Array Radar (APAR) Development

    Science.gov (United States)

    Moore, James; Lee, Wen-Chau; Loew, Eric; Vivekanandan, Jothiram; Grubišić, Vanda; Tsai, Peisang; Dixon, Mike; Emmett, Jonathan; Lord, Mark; Lussier, Louis; Hwang, Kyuil; Ranson, James

    2017-04-01

    The National Center for Atmospheric Research (NCAR) Earth observing Laboratory (EOL) is entering the third year of preliminary system design studies, engineering prototype testing and project management plan preparation for the development of a novel Airborne Phased Array Radar (APAR). This system being designed by NCAR/EOL will be installed and operated on the NSF/NCAR C-130 aircraft. The APAR system will consist of four removable C-band Active Electronically Scanned Arrays (AESA) strategically placed on the fuselage of the aircraft. Each AESA measures approximately 1.5 x 1.9 m and is composed of 3000 active radiating elements arranged in an array of line replaceable units (LRU) to simplify maintenance. APAR will provide unprecedented observations, and in conjunction with the advanced radar data assimilation schema, will be able to address the key science questions to improve understanding and predictability of significant and high-impact weather APAR, operating at C-band, allows the measurement of 3-D kinematics of the more intense portions of storms (e.g. thunderstorm dynamics and tornadic development, tropical cyclone rainband structure and evolution) with less attenuation compared with current airborne Doppler radar systems. Polarimetric measurements are not available from current airborne tail Doppler radars. However, APAR, with dual-Doppler and dual polarization diversity at a lesser attenuating C-band wavelength, will further advance the understanding of the microphysical processes within a variety of precipitation systems. The radar is sensitive enough to provide high resolution measurements of winter storm dynamics and microphysics. The planned APAR development that would bring the system to operational readiness for research community use aboard the C-130 is expected to take 8 years once major funding support is realized. The authors will review the overall APAR design and provide new details of the system based on our Technical Requirements Document

  14. Radar micro-Doppler of wind turbines : Simulation and analysis using rotating linear wire structures

    NARCIS (Netherlands)

    Krasnov, O.A.; Yarovoy, A.

    2015-01-01

    A simple electromagnetic model of wind-turbine's main structural elements as the linear wired structures is developed to simulate the temporal patterns of observed radar return Doppler spectra (micro-Doppler). Using the model, the micro-Doppler for different combinations of the turbines rotation

  15. Predictable progressive Doppler deterioration in IUGR: does it really exist?

    LENUS (Irish Health Repository)

    Unterscheider, Julia

    2013-12-01

    An objective of the Prospective Observational Trial to Optimize Pediatric Health in IUGR (PORTO) study was to evaluate multivessel Doppler changes in a large cohort of intrauterine growth restriction (IUGR) fetuses to establish whether a predictable progressive sequence of Doppler deterioration exists and to correlate these Doppler findings with respective perinatal outcomes.

  16. Accuracy of Gray-scale and Three-dimensional Power Doppler ...

    African Journals Online (AJOL)

    uterine serosa–bladder interface were the best 3D power Doppler parameters for the detection of difficult placental separation, considerable intraoperative ... Moodley et al. concluded that color flow Doppler was more specific in the diagnosis ... Two views of 3D power. Doppler were usually analyzed; lateral view to observe.

  17. Doppler Effect Associated with the Reflection of Light on a Moving Mirror

    OpenAIRE

    Rothenstein, Bernhard; Damian, Ioan

    2005-01-01

    The Doppler Effect associated with the reflection on a moving mirror is reduced to two Doppler Effect experiments involving the incoming incident ray and the outgoing reflected ray or vice-versa. The dependence of the corresponding Doppler factors on the incidence angle on the stationary mirror.

  18. artery complicated The effect of nifedipine on fetal umbilical Doppler ...

    African Journals Online (AJOL)

    1991-02-16

    Feb 16, 1991 ... controlled double-blind study. The effect on maternal blood pressure and the fetal umbilical artery Doppler waveform was studied for 30 minutes before and 30 minutes after administra- tion of the drug or placebo. This dose resulted in a significant drop in maternal blood pressure 30 minutes after administra ...

  19. Comparision of doppler studies in obstetrics with foetal outcome ...

    African Journals Online (AJOL)

    Subjects: One hundread and twenty one consecutive female subjects, between 24 and 443 years of age, at or over 28 weeks gestation, referred to the Radiology Department of Aga Khan University Hospital for obstetric doppler ultrasonography. Main outcome measures: Foetal outcome was defined as poor by using either ...

  20. Augmented Reality Based Doppler Lidar Data Visualization: Promises and Challenges

    Directory of Open Access Journals (Sweden)

    Cherukuru N. W.

    2016-01-01

    As a proof of concept, we used the lidar data from a recent field campaign and developed a smartphone application to view the lidar scan in augmented reality. In this paper, we give a brief methodology of this feasibility study, present the challenges and promises of using AR technology in conjunction with Doppler wind lidars.