Sample records for abmr method

  1. The Spectrum of Renal Allograft Failure

    Chand, Sourabh; Atkinson, David; Collins, Clare; Briggs, David; Ball, Simon; Sharif, Adnan; Skordilis, Kassiani; Vydianath, Bindu; Neil, Desley; Borrows, Richard


    Background Causes of “true” late kidney allograft failure remain unclear as study selection bias and limited follow-up risk incomplete representation of the spectrum. Methods We evaluated all unselected graft failures from 2008–2014 (n = 171; 0–36 years post-transplantation) by contemporary classification of indication biopsies “proximate” to failure, DSA assessment, clinical and biochemical data. Results The spectrum of graft failure changed markedly depending on the timing of allograft failure. Failures within the first year were most commonly attributed to technical failure, acute rejection (with T-cell mediated rejection [TCMR] dominating antibody-mediated rejection [ABMR]). Failures beyond a year were increasingly dominated by ABMR and ‘interstitial fibrosis with tubular atrophy’ without rejection, infection or recurrent disease (“IFTA”). Cases of IFTA associated with inflammation in non-scarred areas (compared with no inflammation or inflammation solely within scarred regions) were more commonly associated with episodes of prior rejection, late rejection and nonadherence, pointing to an alloimmune aetiology. Nonadherence and late rejection were common in ABMR and TCMR, particularly Acute Active ABMR. Acute Active ABMR and nonadherence were associated with younger age, faster functional decline, and less hyalinosis on biopsy. Chronic and Chronic Active ABMR were more commonly associated with Class II DSA. C1q-binding DSA, detected in 33% of ABMR episodes, were associated with shorter time to graft failure. Most non-biopsied patients were DSA-negative (16/21; 76.1%). Finally, twelve losses to recurrent disease were seen (16%). Conclusion This data from an unselected population identifies IFTA alongside ABMR as a very important cause of true late graft failure, with nonadherence-associated TCMR as a phenomenon in some patients. It highlights clinical and immunological characteristics of ABMR subgroups, and should inform clinical practice and

  2. method

    L. M. Kimball


    Full Text Available This paper presents an interior point algorithm to solve the multiperiod hydrothermal economic dispatch (HTED. The multiperiod HTED is a large scale nonlinear programming problem. Various optimization methods have been applied to the multiperiod HTED, but most neglect important network characteristics or require decomposition into thermal and hydro subproblems. The algorithm described here exploits the special bordered block diagonal structure and sparsity of the Newton system for the first order necessary conditions to result in a fast efficient algorithm that can account for all network aspects. Applying this new algorithm challenges a conventional method for the use of available hydro resources known as the peak shaving heuristic.

  3. Method

    Xixin Wang


    Full Text Available ZrO2 nanotube arrays were prepared by anodization method in aqueous electrolyte containing (NH42SO4 and NH4F. The morphology and structure of nanotube arrays were characterized through scanning electron microscope, X-ray diffraction, and infrared spectra analysis. The zirconia nanotube arrays were used as catalyst in esterification reaction. The effects of calcination temperature and electrolyte concentration on catalytic esterification activity have been investigated in detail. Experiments indicate that nanotube arrays have highest catalytic activity when the concentration of (NH42SO4 is 1 mol/L, the concentration of NH4F is 1 wt%, and the calcination temperature is 400°C. Esterification reaction yield of as much as 97% could be obtained under optimal conditions.

  4. Method

    Andrey Gnatov


    Full Text Available Recently repair and recovery vehicle body operations become more and more popular. A special place here is taken by equipment that provides performance of given repair operations. The most interesting things are methods for recovery of car body panels that allow the straightening without disassembling of car body panels and damaging of existing protective coating. Now, there are several technologies for repair and recovery of car body panels without their disassembly and dismantling. The most perspective is magnetic-pulse technology of external noncontact straightening. Basics of magnetic-pulse attraction, both ferromagnetic and nonferromagnetic thin-walled sheet metal, are explored. Inductor system calculation models of magnetic-pulse straightening tools are presented. Final analytical expressions for excited efforts calculation in the tools under consideration are introduced. According to the obtained analytical expressions, numerical evaluations of excited forces were executed. The volumetric epures of the attractive force radial distributions for different types of inductors were built. The practical testing of magnetic-pulse straightening with research tools is given. Using the results of the calculations we can create effective tools for an external magnetic-pulse straightening of car body panels.

  5. Clinical and pathological correlations of C4d immunostaining and its infl uence on the outcome of kidney transplant recipients

    Virna Nowotny Carpio


    Full Text Available INTRODUCTION: C4d is a marker of antibody-mediated rejection (ABMR in kidney allografts, although cellular rejection also have C4d deposits. OBJECTIVE: To correlate C4d expression with clinico-pathological parameters and graft outcomes at three years. METHODS: One hundred forty six renal transplantation recipients with graft biopsies by indication were included. C4d staining was performed by paraffin-immunohistochemistry. Graft function and survival were measured, and predictive variables of the outcome were determined by multivariate Cox regression. RESULTS: C4d staining was detected in 48 (31% biopsies, of which 23 (14.7% had diffuse and 25 (16% focal distribution. Pre-transplantation panel reactive antibodies (%PRA class I and II were significantly higher in C4d positive patients as compared to those C4d negative. Both glomerulitis and pericapillaritis were associated to C4d (p = 0.002 and p < 0.001, respectively. The presence of C4d in biopsies diagnosed as no rejection (NR, acute cellular rejection (ACR or interstitial fibrosis/ tubular atrophy (IF/TA did not impact graft function or survival. Compared to NR, ACR and IF/TA C4d-, patients with ABMR C4d+ had the worst graft survival over 3 years (p = 0.034, but there was no difference between ABMR versus NR, ACR and IF/TA that were C4d positive (p = 0.10. In Cox regression, graft function at biopsy and high %PRA levels were predictors of graft loss. CONCLUSIONS: This study confirmed that C4d staining in kidney graft biopsies is a clinically useful marker of ABMR, with well defined clinical and pathological correlations. The impact of C4d deposition in other histologic diagnoses deserves further investigation.

  6. Vortex methods

    Chorin, A.J. [California Univ., Berkeley, CA (United States). Dept. of Mathematics]|[Lawrence Berkeley Lab., CA (United States)


    Vortex methods originated from the observation that in incompressible inviscid flow vorticity (or, more accurately, circulation) is a conserved quantity, as can be readily deduced from the absence of tangential stresses. Thus, if the vorticity is known at time t=0, one can find the flow at a later time by simply following the vorticity. In this narrow context, a vortex method is a numerical method that follows vorticity. The author restricts himself in these lectures to a special class of numerical vortex methods, those that are based on a Lagrangian transport of vorticity in hydrodynamics by smoothed particles (blobs) and those whose analysis contributes to the understanding of blob methods. Blob methods started in the 1930`s.

  7. Mining Method

    Kim, Young Shik; Lee, Kyung Woon; Kim, Oak Hwan; Kim, Dae Kyung [Korea Institute of Geology Mining and Materials, Taejon (Korea, Republic of)


    The reducing coal market has been enforcing the coal industry to make exceptional rationalization and restructuring efforts since the end of the eighties. To the competition from crude oil and natural gas has been added the growing pressure from rising wages and rising production cost as the workings get deeper. To improve the competitive position of the coal mines against oil and gas through cost reduction, studies to improve mining system have been carried out. To find fields requiring improvements most, the technologies using in Tae Bak Colliery which was selected one of long running mines were investigated and analyzed. The mining method appeared the field needing improvements most to reduce the production cost. The present method, so-called inseam roadway caving method presently is using to extract the steep and thick seam. However, this method has several drawbacks. To solve the problems, two mining methods are suggested for a long term and short term method respectively. Inseam roadway caving method with long-hole blasting method is a variety of the present inseam roadway caving method modified by replacing timber sets with steel arch sets and the shovel loaders with chain conveyors. And long hole blasting is introduced to promote caving. And pillar caving method with chock supports method uses chock supports setting in the cross-cut from the hanging wall to the footwall. Two single chain conveyors are needed. One is installed in front of chock supports to clear coal from the cutting face. The other is installed behind the supports to transport caved coal from behind. This method is superior to the previous one in terms of safety from water-inrushes, production rate and productivity. The only drawback is that it needs more investment. (author). 14 tabs., 34 figs.

  8. Projection Methods

    Wagner, Falko Jens; Poulsen, Mikael Zebbelin


    When trying to solve a DAE problem of high index with more traditional methods, it often causes instability in some of the variables, and finally leads to breakdown of convergence and integration of the solution. This is nicely shown in [ESF98, p. 152 ff.].This chapter will introduce projection...... methods as a way of handling these special problems. It is assumed that we have methods for solving normal ODE systems and index-1 systems....

  9. Computing methods

    Berezin, I S


    Computing Methods, Volume 2 is a five-chapter text that presents the numerical methods of solving sets of several mathematical equations. This volume includes computation sets of linear algebraic equations, high degree equations and transcendental equations, numerical methods of finding eigenvalues, and approximate methods of solving ordinary differential equations, partial differential equations and integral equations.The book is intended as a text-book for students in mechanical mathematical and physics-mathematical faculties specializing in computer mathematics and persons interested in the

  10. Method 59

    Kjellsson, G.


    OCDE/GD(94)41. Er supplerende rapport til rapport: The OECD Workshop on Methods for Monitoring Organisms in the Environment, Ottawa 14-17 September 1992. Environment Monograph 90.......OCDE/GD(94)41. Er supplerende rapport til rapport: The OECD Workshop on Methods for Monitoring Organisms in the Environment, Ottawa 14-17 September 1992. Environment Monograph 90....

  11. Method Mixins

    Ernst, Erik


    , where traditional invocation is optimized for as-is reuse of existing behavior. Tight coupling reduces flexibility, and traditional invocation tightly couples transfer of information and transfer of control. Method mixins decouple these two kinds of transfer, thereby opening the doors for new kinds......The world of programming has been conquered by the procedure call mechanism, including object-oriented method invocation which is a procedure call in context of an object. This paper presents an alternative, method mixin invocations, that is optimized for flexible creation of composite behavior...

  12. Method Mixins

    Ernst, Erik


    invocation is optimized for as-is reuse of existing behavior. Tight coupling reduces flexibility, and traditional invocation tightly couples transfer of information and transfer of control. Method mixins decouple these two kinds of transfer, thereby opening the doors for new kinds of abstraction and reuse......The procedure call mechanism has conquered the world of programming, with object-oriented method invocation being a procedure call in context of an object. This paper presents an alternative, method mixin invocations, that is optimized for flexible creation of composite behavior, where traditional...

  13. Dosimetry methods

    McLaughlin, W.L.; Miller, A.; Kovacs, A.;


    Chemical and physical radiation dosimetry methods, used for the measurement of absorbed dose mainly during the practical use of ionizing radiation, are discussed with respect to their characteristics and fields of application.......Chemical and physical radiation dosimetry methods, used for the measurement of absorbed dose mainly during the practical use of ionizing radiation, are discussed with respect to their characteristics and fields of application....

  14. Ensemble Methods

    Re, Matteo; Valentini, Giorgio


    Ensemble methods are statistical and computational learning procedures reminiscent of the human social learning behavior of seeking several opinions before making any crucial decision. The idea of combining the opinions of different "experts" to obtain an overall “ensemble” decision is rooted in our culture at least from the classical age of ancient Greece, and it has been formalized during the Enlightenment with the Condorcet Jury Theorem[45]), which proved that the judgment of a committee is superior to those of individuals, provided the individuals have reasonable competence. Ensembles are sets of learning machines that combine in some way their decisions, or their learning algorithms, or different views of data, or other specific characteristics to obtain more reliable and more accurate predictions in supervised and unsupervised learning problems [48,116]. A simple example is represented by the majority vote ensemble, by which the decisions of different learning machines are combined, and the class that receives the majority of “votes” (i.e., the class predicted by the majority of the learning machines) is the class predicted by the overall ensemble [158]. In the literature, a plethora of terms other than ensembles has been used, such as fusion, combination, aggregation, and committee, to indicate sets of learning machines that work together to solve a machine learning problem [19,40,56,66,99,108,123], but in this chapter we maintain the term ensemble in its widest meaning, in order to include the whole range of combination methods. Nowadays, ensemble methods represent one of the main current research lines in machine learning [48,116], and the interest of the research community on ensemble methods is witnessed by conferences and workshops specifically devoted to ensembles, first of all the multiple classifier systems (MCS) conference organized by Roli, Kittler, Windeatt, and other researchers of this area [14,62,85,149,173]. Several theories have been

  15. Statistical methods

    Szulc, Stefan


    Statistical Methods provides a discussion of the principles of the organization and technique of research, with emphasis on its application to the problems in social statistics. This book discusses branch statistics, which aims to develop practical ways of collecting and processing numerical data and to adapt general statistical methods to the objectives in a given field.Organized into five parts encompassing 22 chapters, this book begins with an overview of how to organize the collection of such information on individual units, primarily as accomplished by government agencies. This text then

  16. Spectral Methods

    Shen, Jie; Wang, Li-Lian


    Along with finite differences and finite elements, spectral methods are one of the three main methodologies for solving partial differential equations on computers. This book provides a detailed presentation of basic spectral algorithms, as well as a systematical presentation of basic convergence theory and error analysis for spectral methods. Readers of this book will be exposed to a unified framework for designing and analyzing spectral algorithms for a variety of problems, including in particular high-order differential equations and problems in unbounded domains. The book contains a large

  17. Statistical methods

    Freund, Rudolf J; Wilson, William J


    Statistical Methods, 3e provides students with a working introduction to statistical methods offering a wide range of applications that emphasize the quantitative skills useful across many academic disciplines. This text takes a classic approach emphasizing concepts and techniques for working out problems and intepreting results. The book includes research projects, real-world case studies, numerous examples and data exercises organized by level of difficulty. This text requires that a student be familiar with algebra. New to this edition: NEW expansion of exercises a

  18. Characterization methods

    Glass, J.T. [North Carolina State Univ., Raleigh (United States)


    Methods discussed in this compilation of notes and diagrams are Raman spectroscopy, scanning electron microscopy, transmission electron microscopy, and other surface analysis techniques (auger electron spectroscopy, x-ray photoelectron spectroscopy, electron energy loss spectroscopy, and scanning tunnelling microscopy). A comparative evaluation of different techniques is performed. In-vacuo and in-situ analyses are described.

  19. Radiofluorination method


    A method of conducting radiofluorination of a substrate, comprising the steps of: (a) contacting an aqueous solution of [18F] fluoride with a polymer supported phosphazene base for sufficient time for trapping of [18F] fluoride on the polymer supported phosphazene base; and (b) contacting...

  20. Digital Methods

    Rogers, R.


    In Digital Methods, Richard Rogers proposes a methodological outlook for social and cultural scholarly research on the Web that seeks to move Internet research beyond the study of online culture. It is not a toolkit for Internet research, or operating instructions for a software package; it deals wi

  1. Numerical methods

    Dahlquist, Germund


    ""Substantial, detailed and rigorous . . . readers for whom the book is intended are admirably served."" - MathSciNet (Mathematical Reviews on the Web), American Mathematical Society.Practical text strikes fine balance between students' requirements for theoretical treatment and needs of practitioners, with best methods for large- and small-scale computing. Prerequisites are minimal (calculus, linear algebra, and preferably some acquaintance with computer programming). Text includes many worked examples, problems, and an extensive bibliography.

  2. Multiplexed color-coded probe-based gene expression assessment for clinical molecular diagnostics in formalin-fixed paraffin-embedded human renal allograft tissue.

    Adam, Benjamin; Afzali, Bahman; Dominy, Katherine M; Chapman, Erin; Gill, Reeda; Hidalgo, Luis G; Roufosse, Candice; Sis, Banu; Mengel, Michael


    Histopathologic diagnoses in transplantation can be improved with molecular testing. Preferably, molecular diagnostics should fit into standard-of-care workflows for transplant biopsies, that is, formalin-fixed paraffin-embedded (FFPE) processing. The NanoString(®) gene expression platform has recently been shown to work with FFPE samples. We aimed to evaluate its methodological robustness and feasibility for gene expression studies in human FFPE renal allograft samples. A literature-derived antibody-mediated rejection (ABMR) 34-gene set, comprised of endothelial, NK cell, and inflammation transcripts, was analyzed in different retrospective biopsy cohorts and showed potential to molecularly discriminate ABMR cases, including FFPE samples. NanoString(®) results were reproducible across a range of RNA input quantities (r = 0.998), with different operators (r = 0.998), and between different reagent lots (r = 0.983). There was moderate correlation between NanoString(®) with FFPE tissue and quantitative reverse transcription polymerase chain reaction (qRT-PCR) with corresponding dedicated fresh-stabilized tissue (r = 0.487). Better overall correlation with histology was observed with NanoString(®) (r = 0.354) than with qRT-PCR (r = 0.146). Our results demonstrate the feasibility of multiplexed gene expression quantification from FFPE renal allograft tissue. This represents a method for prospective and retrospective validation of molecular diagnostics and its adoption in clinical transplantation pathology.

  3. Markers of Endothelial-to-Mesenchymal Transition: Evidence for Antibody-Endothelium Interaction during Antibody-Mediated Rejection in Kidney Recipients.

    Xu-Dubois, Yi-Chun; Peltier, Julie; Brocheriou, Isabelle; Suberbielle-Boissel, Caroline; Djamali, Arjang; Reese, Shannon; Mooney, Nuala; Keuylian, Zela; Lion, Julien; Ouali, Nacéra; Levy, Pierre P; Jouanneau, Chantal; Rondeau, Eric; Hertig, Alexandre


    Antibody-mediated rejection (ABMR) is a leading cause of allograft loss. Treatment efficacy depends on accurate diagnosis at an early stage. However, sensitive and reliable markers of antibody-endothelium interaction during ABMR are not available for routine use. Using immunohistochemistry, we retrospectively studied the diagnostic value of three markers of endothelial-to-mesenchymal transition (EndMT), fascin1, vimentin, and heat shock protein 47, for ABMR in 53 renal transplant biopsy specimens, including 20 ABMR specimens, 24 cell-mediated rejection specimens, and nine normal grafts. We validated our results in an independent set of 74 unselected biopsy specimens. Endothelial cells of the peritubular capillaries in grafts with ABMR expressed fascin1, vimentin, and heat shock protein 47 strongly, whereas those from normal renal grafts did not. The level of EndMT marker expression was significantly associated with current ABMR criteria, including capillaritis, glomerulitis, peritubular capillary C4d deposition, and donor-specific antibodies. These markers allowed us to identify C4d-negative ABMR and to predict late occurrence of disease. EndMT markers were more specific than capillaritis for the diagnosis and prognosis of ABMR and predicted late (up to 4 years after biopsy) renal graft dysfunction and proteinuria. In the independent set of 74 renal graft biopsy specimens, the EndMT markers for the diagnosis of ABMR had a sensitivity of 100% and a specificity of 85%. Fascin1 expression in peritubular capillaries was also induced in a rat model of ABMR. In conclusion, EndMT markers are a sensitive and reliable diagnostic tool for detecting endothelial activation during ABMR and predicting late loss of allograft function.

  4. Birth Control Methods

    ... Home A-Z Health Topics Birth control methods Birth control methods > A-Z Health Topics Birth control methods ... To receive Publications email updates Enter email Submit Birth control methods Birth control (contraception) is any method, medicine, ...

  5. The clinical method and the scientific method

    José Arteaga Herrera


    Full Text Available This paper is the chapter dedicated to the scientific method and the clinical method in the authors’ Handbook “Teaching of Clinics”. Philosophycal principles of the scientific method and its stages are presented as well as the clinical method as a scientific one and its stages. A relationship between the clinical method and the medical record is established, the role of technology in the clinical method is stated and the most frequent mistakes when applying it in clinical practice are provided. Finally, the teaching of the clinical method and the appropriate settings to do it are discussed.

  6. An Inexact Halley's Method


    An inexact Halley's method-Halley-PCG(preconditioned conjugate gradient) method is proposed for solving the systems of linear equations for improved Halley method either by Cholesky factorization exactly or by preconditioned conjugate gradient method approximately. The convergence result is given and the efficiency of the method compared to the improved Halley's method is shown.

  7. From Method to Post Method: A Panacea!

    Masouleh, Nima Shakouri


    The foundation of language teaching has undergone many changes. The rise and fall of language teaching methods depends upon a variety of factors extrinsic to a method itself and often reflects the influence of profit-seekers and promoters, as well as the forces of the intellectual marketplace. There was always a source of contention among people…

  8. Meshless Methods Coupled with Other Numerical Methods

    Y.T.GU; G.R.LIU


    Meshless or mesh-free (or shorten as MFree) methods have been proposed and achieved remarkable progress over the past few years. The idea of combining MFree methods with other existing numerical techniques such as the finite element method (FEM) and the boundary element method (BEM), is naturally of great interest in many practical applications. However, the shape functions used in some MFree methods do not have the Kronecker delta function property. In order to satisfy the combined conditions of displacement compatibility, two numerical techniques, using the hybrid displacement shape function and the modified variational form, are developed and discussed in this paper. In the first technique, the original MFree shape functions are modified to the hybrid forms that possess the Kronecker delta function property. In the second technique, the displacement compatibility is satisfied via a modified variational form based on the Lagrange multiplier method. Formulations of several coupled methods are presented. Numerical examples are presented to demonstrate the effectiveness of the present coupling methods.

  9. Ensemble Data Mining Methods

    National Aeronautics and Space Administration — Ensemble Data Mining Methods, also known as Committee Methods or Model Combiners, are machine learning methods that leverage the power of multiple models to achieve...

  10. The Multidimensional WKB Method.

    Knudson, Stephen K.; Noid, D. W.


    Discusses a new method for determining the eigenvalues of the Schroedinger equation when the potential energy function does not have a simple form. Describes the mathematical methods and provides an application. Lists limitations to the method. (MVL)


    Wei-nan E; Ping-bing Ming


    The heterogeneous multiscale method gives a general framework for the analysis of multiscale methods. In this paper, we demonstrate this by applying this framework to two canonical problems: The elliptic problem with multiscale coefficients and the quasicontinuum method.

  12. Simplifications of CQC method and CCQC method

    Yu Ruifang; Zhou Xiyuan


    The response-spectrum mode superposition method is widely used for seismic response analyses of linear systems. In using this method, the complete quadratic combination (CQC) is adopted for classically damped linear systems and the complex complete quadratic combination (CCQC) formula is adopted for non-classically damped linear systems.However, in both cases, the calculation of seismic response analyses is very time consuming. In this paper, the variation of the modal correlation coefficients of displacement, velocity and displacement-velocity with frequency and damping ratios of two modes of interest are studied, Moreover, the calculation errors generated by using CQC and square-root-of-the-sum-of-the-squares (SRSS) methods (or CCQC and CSRSS methods) for different damping combinations are compared. In these analyses,some boundary lines for classically and non-classically damped systems are plotted to distinguish the allowed minimum frequency ratio at given geometric mean of the damping ratios of both modes if their relativity is neglected. Furthermore,the simplified method, which is a special mode quadratic combination method considering only relativity of adjacent modes in CQC method and named simplified CQC or partial quadratic combination (PQC) method for classically damped linear system, is proposed to improve computational efficiency, and the criterion for determination of how many correlated modes should be adopted is proposed. Similarly, the simplified CCQC or complex partial quadratic combination (CPQC) method for the non-classically damped linear system and the corresponding criterion are also deduced. Finally, a numerical example is given to illustrate the applicability, computational accuracy and efficiency of the PQC and CPQC methods.

  13. Simulations using meshfree methods

    P, Kirana Kumara


    In this paper, attempt is made to solve a few problems using the Polynomial Point Collocation Method (PPCM), the Radial Point Collocation Method (RPCM), Smoothed Particle Hydrodynamics (SPH), and the Finite Point Method (FPM). A few observations on the accuracy of these methods are recorded. All the simulations in this paper are three dimensional linear elastostatic simulations, without accounting for body forces.

  14. Numerical Methods for Multilattices

    Abdulle, Assyr; Shapeev, Alexander V


    Among the efficient numerical methods based on atomistic models, the quasicontinuum (QC) method has attracted growing interest in recent years. The QC method was first developed for crystalline materials with Bravais lattice and was later extended to multilattices (Tadmor et al, 1999). Another existing numerical approach to modeling multilattices is homogenization. In the present paper we review the existing numerical methods for multilattices and propose another concurrent macro-to-micro method in the homogenization framework. We give a unified mathematical formulation of the new and the existing methods and show their equivalence. We then consider extensions of the proposed method to time-dependent problems and to random materials.

  15. Inflow Turbulence Generation Methods

    Wu, Xiaohua


    Research activities on inflow turbulence generation methods have been vigorous over the past quarter century, accompanying advances in eddy-resolving computations of spatially developing turbulent flows with direct numerical simulation, large-eddy simulation (LES), and hybrid Reynolds-averaged Navier-Stokes–LES. The weak recycling method, rooted in scaling arguments on the canonical incompressible boundary layer, has been applied to supersonic boundary layer, rough surface boundary layer, and microscale urban canopy LES coupled with mesoscale numerical weather forecasting. Synthetic methods, originating from analytical approximation to homogeneous isotropic turbulence, have branched out into several robust methods, including the synthetic random Fourier method, synthetic digital filtering method, synthetic coherent eddy method, and synthetic volume forcing method. This article reviews major progress in inflow turbulence generation methods with an emphasis on fundamental ideas, key milestones, representative applications, and critical issues. Directions for future research in the field are also highlighted.

  16. Advanced differential quadrature methods

    Zong, Zhi


    Modern Tools to Perform Numerical DifferentiationThe original direct differential quadrature (DQ) method has been known to fail for problems with strong nonlinearity and material discontinuity as well as for problems involving singularity, irregularity, and multiple scales. But now researchers in applied mathematics, computational mechanics, and engineering have developed a range of innovative DQ-based methods to overcome these shortcomings. Advanced Differential Quadrature Methods explores new DQ methods and uses these methods to solve problems beyond the capabilities of the direct DQ method.After a basic introduction to the direct DQ method, the book presents a number of DQ methods, including complex DQ, triangular DQ, multi-scale DQ, variable order DQ, multi-domain DQ, and localized DQ. It also provides a mathematical compendium that summarizes Gauss elimination, the Runge-Kutta method, complex analysis, and more. The final chapter contains three codes written in the FORTRAN language, enabling readers to q...

  17. Applied Bayesian Hierarchical Methods

    Congdon, Peter D


    Bayesian methods facilitate the analysis of complex models and data structures. Emphasizing data applications, alternative modeling specifications, and computer implementation, this book provides a practical overview of methods for Bayesian analysis of hierarchical models.

  18. Dissolution Methods Database

    U.S. Department of Health & Human Services — For a drug product that does not have a dissolution test method in the United States Pharmacopeia (USP), the FDA Dissolution Methods Database provides information on...

  19. Dissolution Methods Database

    U.S. Department of Health & Human Services — For a drug product that does not have a dissolution test method in the United States Pharmacopeia (USP), the FDA Dissolution Methods Database provides information...

  20. Simulated floating zone method

    Ozawa, Ryo; Kato, Yasuyuki; Motome, Yukitoshi


    This paper provides the simulated floating zone (SFZ) method that is an efficient simulation technique to obtain thermal equilibrium states, especially useful when domain formation prevents the system from reaching a spatially-uniform stable state. In the SFZ method, the system is heated up locally, and the heated region is steadily shifted, similar to the floating zone method for growing a single crystal with less lattice defect and impurity in experiments. We demonstrate that the SFZ method...

  1. Consumer Behavior Research Methods

    Chrysochou, Polymeros


    This chapter starts by distinguishing consumer behavior research methods based on the type of data used, being either secondary or primary. Most consumer behavior research studies phenomena that require researchers to enter the field and collect data on their own, and therefore the chapter...... of the methods and how to improve quality in consumer behavior research methods....

  2. Geobacteraceae strains and methods

    Lovley, Derek R.; Nevin, Kelly P.; Yi, Hana


    Embodiments of the present invention provide a method of producing genetically modified strains of electricigenic microbes that are specifically adapted for the production of electrical current in microbial fuel cells, as well as strains produced by such methods and fuel cells using such strains. In preferred embodiments, the present invention provides genetically modified strains of Geobacter sulfurreducens and methods of using such strains.

  3. Mixed methods research.

    Halcomb, Elizabeth; Hickman, Louise


    Mixed methods research involves the use of qualitative and quantitative data in a single research project. It represents an alternative methodological approach, combining qualitative and quantitative research approaches, which enables nurse researchers to explore complex phenomena in detail. This article provides a practical overview of mixed methods research and its application in nursing, to guide the novice researcher considering a mixed methods research project.

  4. Mimetic discretization methods

    Castillo, Jose E


    To help solve physical and engineering problems, mimetic or compatible algebraic discretization methods employ discrete constructs to mimic the continuous identities and theorems found in vector calculus. Mimetic Discretization Methods focuses on the recent mimetic discretization method co-developed by the first author. Based on the Castillo-Grone operators, this simple mimetic discretization method is invariably valid for spatial dimensions no greater than three. The book also presents a numerical method for obtaining corresponding discrete operators that mimic the continuum differential and

  5. The Generalized Sturmian Method

    Avery, James Emil


    generations of researchers were left to work out how to achieve this ambitious goal for molecular systems of ever-increasing size. This book focuses on non-mainstream methods to solve the molecular electronic Schrödinger equation. Each method is based on a set of core ideas and this volume aims to explain...... these ideas clearly so that they become more accessible. By bringing together these non-standard methods, the book intends to inspire graduate students, postdoctoral researchers and academics to think of novel approaches. Is there a method out there that we have not thought of yet? Can we design a new method...

  6. Numerical methods using Matlab

    Gupta, Abhishek


    Numerical Methods with MATLAB provides a highly-practical reference work to assist anyone working with numerical methods. A wide range of techniques are introduced, their merits discussed and fully working MATLAB code samples supplied to demonstrate how they can be coded and applied. Numerical methods have wide applicability across many scientific, mathematical, and engineering disciplines and are most often employed in situations where working out an exact answer to the problem by another method is impractical. Numerical Methods with MATLAB presents each topic in a concise and readable

  7. Design Methods in Practice

    Jensen, Torben Elgaard; Andreasen, Mogens Myrup


    The paper challenges the dominant and widespread view that a good design method will guarantee a systematic approach as well as certain results. First, it explores the substantial differences between on the one hand the conception of methods implied in Pahl & Beitz’s widely recognized text book...... subject to change; The goals of methods are less stable than assumed. The paper finally suggests that ethnomethodology and similar approaches direct our attention to the fact that method use is always a situated and socially interactive affair. It is crucial to attend to these dimensions of method use...... on engineering design, and on the other hand the understanding of method use, which has emerged from micro-sociological studies of practice (ethnomethodology). Second, it reviews a number of case studies conducted by engineering students, who were instructed to investigate the actual use of design methods...

  8. Methods of Software Verification

    R. E. Gurin


    Full Text Available This article is devoted to the problem of software verification (SW. Methods of software verification designed to check the software for compliance with the stated requirements such as correctness, system security and system adaptability to small changes in the environment, portability and compatibility, etc. These are various methods both by the operation process and by the way of achieving result. The article describes the static and dynamic methods of software verification and paid attention to the method of symbolic execution. In its review of static analysis are discussed and described the deductive method, and methods for testing the model. A relevant issue of the pros and cons of a particular method is emphasized. The article considers classification of test techniques for each method. In this paper we present and analyze the characteristics and mechanisms of the static analysis of dependencies, as well as their views, which can reduce the number of false positives in situations where the current state of the program combines two or more states obtained both in different paths of execution and in working with multiple object values. Dependences connect various types of software objects: single variables, the elements of composite variables (structure fields, array elements, the size of the heap areas, the length of lines, the number of initialized array elements in the verification code using static methods. The article pays attention to the identification of dependencies within the framework of the abstract interpretation, as well as gives an overview and analysis of the inference tools.Methods of dynamic analysis such as testing, monitoring and profiling are presented and analyzed. Also some kinds of tools are considered which can be applied to the software when using the methods of dynamic analysis. Based on the work a conclusion is drawn, which describes the most relevant problems of analysis techniques, methods of their solutions and

  9. Performative Schizoid Method

    Svabo, Connie


    A performative schizoid method is developed as a method contribution to performance as research. The method is inspired by contemporary research in the human and social sciences urging experimentation and researcher engagement with creative and artistic practice. In the article, the method...... is presented and an example is provided of a first exploratory engagement with it. The method is used in a specific project Becoming Iris, making inquiry into arts-based knowledge creation during a three month visiting scholarship at a small, independent visual art academy. Using the performative schizoid...... method in Becoming Iris results in four audio-visual and performance-based productions, centered on an emergent theme of the scholartist as a bird in borrowed feathers. Interestingly, the moral lesson of the fable about the vain jackdaw, who dresses in borrowed peacock feathers and becomes a castout...

  10. Phenomenographic Research Method

    Erdem ÇEKMEZ


    Full Text Available Phenomenography, an approach to educational research, emerged from the studies carried out by Ference Marton and his colleagues at the University of Göteborg, Sweden, in the early 1970s. Phenomenography is the empirical study of the different ways in which people experience, perceive, apprehend, understand, conceptualize various phenomena in the world around them. Not only this method has been used much in educational researches in Turkey, but also the books about research methods do not provide detailed information about this method in details. This study explains the aim, characteristics, historical background and how to ensure the generalization, validity and reliability of phenomenographic research outcomes, besides mentions to the studies in which phenomenographic research method was used. In addition, the differences and similarities between this method and methods similar to phenomenology are explained.

  11. Exoplanet Detection Methods

    Wright, Jason T


    This chapter reviews various methods of detecting planetary companions to stars from an observational perspective, focusing on radial velocities, astrometry, direct imaging, transits, and gravitational microlensing. For each method, this chapter first derives or summarizes the basic observable phenomena that are used to infer the ex- istence of planetary companions, as well as the physical properties of the planets and host stars that can be derived from the measurement of these signals. This chapter then outlines the general experimental requirements to robustly detect the signals us- ing each method, by comparing their magnitude to the typical sources of measurement uncertainty. This chapter goes on to compare the various methods to each other by outlining the regions of planet and host star parameter space where each method is most sensitive, stressing the complementarity of the ensemble of the methods at our disposal. Finally, there is a brief review of the history of the young exoplanet field, from the f...

  12. The Box Method

    Nielsen, Peter Vilhelm

    The velocity level in a room ventilated by jet ventilation is strongly influenced by the supply conditions. The momentum flow in the supply jets controls the air movement in the room and, therefore, it is very important that the inlet conditions and the numerical method can generate a satisfactory...... description of this momentum flow. The Box Method is a practical method for the description of an Air Terminal Device which will save grid points and ensure the right level of the momentum flow....

  13. The Schwinger Variational Method

    Huo, Winifred M.


    Variational methods have proven invaluable in theoretical physics and chemistry, both for bound state problems and for the study of collision phenomena. For collisional problems they can be grouped into two types: those based on the Schroedinger equation and those based on the Lippmann-Schwinger equation. The application of the Schwinger variational (SV) method to e-molecule collisions and photoionization has been reviewed previously. The present chapter discusses the implementation of the SV method as applied to e-molecule collisions.

  14. Applied iterative methods

    Hageman, Louis A


    This graduate-level text examines the practical use of iterative methods in solving large, sparse systems of linear algebraic equations and in resolving multidimensional boundary-value problems. Assuming minimal mathematical background, it profiles the relative merits of several general iterative procedures. Topics include polynomial acceleration of basic iterative methods, Chebyshev and conjugate gradient acceleration procedures applicable to partitioning the linear system into a "red/black" block form, adaptive computational algorithms for the successive overrelaxation (SOR) method, and comp

  15. Studying Aid: Some Methods

    D.R. Gasper (Des)


    textabstractINVESTIGATING IDEAS, IDEOLOGIES AND PRACTICES This paper presents some methods for trying to make sense of international aid and of its study.1 Some of the methods may be deemed ethnographic; the others are important partners to them, but rather different. In the course of discussing q



    The present invention relates to a method for making Cheddar type and Continental type cheese with an adjunct culture comprising a Lactobacillus helveticus strain.......The present invention relates to a method for making Cheddar type and Continental type cheese with an adjunct culture comprising a Lactobacillus helveticus strain....

  17. Research Methods in Education

    Check, Joseph; Schutt, Russell K.


    "Research Methods in Education" introduces research methods as an integrated set of techniques for investigating questions about the educational world. This lively, innovative text helps students connect technique and substance, appreciate the value of both qualitative and quantitative methodologies, and make ethical research decisions.…

  18. Improved nonlinear prediction method

    Adenan, Nur Hamiza; Md Noorani, Mohd Salmi


    The analysis and prediction of time series data have been addressed by researchers. Many techniques have been developed to be applied in various areas, such as weather forecasting, financial markets and hydrological phenomena involving data that are contaminated by noise. Therefore, various techniques to improve the method have been introduced to analyze and predict time series data. In respect of the importance of analysis and the accuracy of the prediction result, a study was undertaken to test the effectiveness of the improved nonlinear prediction method for data that contain noise. The improved nonlinear prediction method involves the formation of composite serial data based on the successive differences of the time series. Then, the phase space reconstruction was performed on the composite data (one-dimensional) to reconstruct a number of space dimensions. Finally the local linear approximation method was employed to make a prediction based on the phase space. This improved method was tested with data series Logistics that contain 0%, 5%, 10%, 20% and 30% of noise. The results show that by using the improved method, the predictions were found to be in close agreement with the observed ones. The correlation coefficient was close to one when the improved method was applied on data with up to 10% noise. Thus, an improvement to analyze data with noise without involving any noise reduction method was introduced to predict the time series data.

  19. Data center cooling method

    Chainer, Timothy J.; Dang, Hien P.; Parida, Pritish R.; Schultz, Mark D.; Sharma, Arun


    A method aspect for removing heat from a data center may use liquid coolant cooled without vapor compression refrigeration on a liquid cooled information technology equipment rack. The method may also include regulating liquid coolant flow to the data center through a range of liquid coolant flow values with a controller-apparatus based upon information technology equipment temperature threshold of the data center.

  20. Methods for data classification

    Garrity, George; Lilburn, Timothy G.


    The present invention provides methods for classifying data and uncovering and correcting annotation errors. In particular, the present invention provides a self-organizing, self-correcting algorithm for use in classifying data. Additionally, the present invention provides a method for classifying biological taxa.

  1. Method of forming nanodielectrics

    Tuncer, Enis [Knoxville, TN; Polyzos, Georgios [Oak Ridge, TN


    A method of making a nanoparticle filled dielectric material. The method includes mixing nanoparticle precursors with a polymer material and reacting the nanoparticle mixed with the polymer material to form nanoparticles dispersed within the polymer material to form a dielectric composite.

  2. Soybean allergen detection methods

    Pedersen, Mona H; Holzhauser, Thomas; Bisson, Caroline


    Soybean containing products are widely consumed, thus reliable methods for detection of soy in foods are needed in order to make appropriate risk assessment studies to adequately protect soy allergic patients. Six methods were compared using eight food products with a declared content of soy...

  3. The Method of Archimedes.

    Del Grande, John


    Describes the method that Archimedes utilized to calculate the volumes of spheres and other solids. The method found the volume of a sphere by comparing the mass of parallel slices of a sphere and a cone with that of a cylinder of known mass. (MDH)




  5. Noise-Measuring Method

    Diamond, J. M.


    A noise-measuring method based on the use of a calibrated noise generator and an output meter with a special scale is described. The method eliminates the effect of noise contributions occurring in the circuits following the device under test....

  6. Engaging with mobile methods

    Jensen, Martin Trandberg


    This chapter showcases how mobile methods are more than calibrated techniques awaiting application by tourism researchers, but productive in the enactment of the mobile (Law and Urry, 2004). Drawing upon recent findings deriving from a PhD course on mobility and mobile methods it reveals...... the conceptual ambiguousness of the term ‘mobile methods’. In order to explore this ambiguousness the chapter provides a number of examples deriving from tourism research, to explore how mobile methods are always entangled in ideologies, predispositions, conventions and practice-realities. Accordingly......, the engagements with methods are acknowledged to be always political and contextual, reminding us to avoid essentialist discussions regarding research methods. Finally, the chapter draws on recent fieldwork to extend developments in mobilities-oriented tourism research, by employing auto-ethnography to call...

  7. Methods in Modern Biophysics

    Nölting, Bengt


    Incorporating recent dramatic advances, this textbook presents a fresh and timely introduction to modern biophysical methods. An array of new, faster and higher-power biophysical methods now enables scientists to examine the mysteries of life at a molecular level. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, proteomics, and protein folding and structure. Incorporating much information previously unavailable in tutorial form, Nölting employs worked examples and 267 illustrations to fully detail the techniques and their underlying mechanisms. Methods in Modern Biophysics is written for advanced undergraduate and graduate students, postdocs, researchers, lecturers and professors in biophysics, biochemistry and related fields. Special features in the 2nd edition: • Illustrates the high-resolution methods for ultrashort-living protei...

  8. Cooperative method development

    Dittrich, Yvonne; Rönkkö, Kari; Eriksson, Jeanette;


    research is not easily combined with the improvement orientation of an engineering discipline. During the last 6 years, we have applied an approach we call `cooperative method development', which combines qualitative social science fieldwork, with problem-oriented method, technique and process improvement....... The action research based approach focusing on shop floor software development practices allows an understanding of how contextual contingencies influence the deployment and applicability of methods, processes and techniques. This article summarizes the experiences and discusses the further development......The development of methods tools and process improvements is best to be based on the understanding of the development practice to be supported. Qualitative research has been proposed as a method for understanding the social and cooperative aspects of software development. However, qualitative...

  9. Adaptive method of lines

    Saucez, Ph


    The general Method of Lines (MOL) procedure provides a flexible format for the solution of all the major classes of partial differential equations (PDEs) and is particularly well suited to evolutionary, nonlinear wave PDEs. Despite its utility, however, there are relatively few texts that explore it at a more advanced level and reflect the method''s current state of development.Written by distinguished researchers in the field, Adaptive Method of Lines reflects the diversity of techniques and applications related to the MOL. Most of its chapters focus on a particular application but also provide a discussion of underlying philosophy and technique. Particular attention is paid to the concept of both temporal and spatial adaptivity in solving time-dependent PDEs. Many important ideas and methods are introduced, including moving grids and grid refinement, static and dynamic gridding, the equidistribution principle and the concept of a monitor function, the minimization of a functional, and the moving finite elem...

  10. Methods for age estimation

    D. Sümeyra Demirkıran


    Full Text Available Concept of age estimation plays an important role on both civil law and regulation of criminal behaviors. In forensic medicine, age estimation is practiced for individual requests as well for request of the court. In this study it is aimed to compile the methods of age estimation and to make recommendations for the solution of the problems encountered. In radiological method the epiphyseal lines of the bones and views of the teeth are used. In order to estimate the age by comparing bone radiographs; Greulich-Pyle Atlas (GPA, Tanner-Whitehouse Atlas (TWA and “Adli Tıpta Yaş Tayini (ATYT” books are used. Bone age is found to be 2 years older averagely than chronologic age, especially in puberty, according to the forensic age estimations described in the ATYT book. For the age estimation with teeth, Demirjian method is used. In time different methods are developed by modifying Demirjian method. However no accurate method was found. Histopathological studies are done on bone marrow cellularity and dermis cells. No correlation was found between histopathoogical findings and choronologic age. Important ethical and legal issues are brought with current age estimation methods especially in teenage period. Therefore it is required to prepare atlases of bone age compatible with our society by collecting the findings of the studies in Turkey. Another recommendation could be to pay attention to the courts of age raising trials of teenage women and give special emphasis on birth and population records


    Orlov A. I.


    Full Text Available We have given a critical analysis of statistical models and methods for processing text information in historical records to establish the times when there were certain events, ie, to build science-based chronology. There are three main kinds of sources of knowledge of ancient history: ancient texts, the remains of material culture and traditions. The specific date of the extracted by archaeologists objects in most cases can not be found. The group of Academician A.T. Fomenko has developed and applied new statistical methods for analysis of historical texts (Chronicle, based on the intensive use of computer technology. Two major scientific results were: the majority of historical records that we know now, are duplicated (in particular, chronicles, describing the so-called "Ancient Rome" and "Middle Ages", talking about the same events; the known historical chronicles tell us about real events, separated from the present time for not more than 1000 years. It was found that chronicles describing the history of "ancient times" and "Middle Ages" and the chronicle of Chinese history and the history of various European countries do not talk about different, but about the same events. We have the attempt of a new dating of historical events and restoring the true history of human society based on new data. From the standpoint of statistical methods of historical records and images of their fragments – they are special cases of non-numeric objects of nature. Therefore, developed by the group of A.T. Fomenko computer-statistical methods are the part of non-numerical statistics. We have considered some methods of statistical analysis of chronicles applied by the group of A.T. Fomenko: correlation method of maximums; dynasties method; the method of attenuation frequency; questionnaire method codes. New chronology allows us to understand much of the battle of ideas in modern science and mass consciousness. It becomes clear the root cause of cautious

  12. Structural Reliability Methods

    Ditlevsen, Ove Dalager; Madsen, H. O.

    of structural reliability, including the theoretical basis for these methods. Partial safety factor codes under current practice are briefly introduced and discussed. A probabilistic code format for obtaining a formal reliability evaluation system that catches the most essential features of the nature......The structural reliability methods quantitatively treat the uncertainty of predicting the behaviour and properties of a structure given the uncertain properties of its geometry, materials, and the actions it is supposed to withstand. This book addresses the probabilistic methods for evaluation...

  13. Methods in Bioengineering

    Jayaraman, Arul


    This volume provides a detailed look at the two main aspects of systems biology: the design of sophisticated experimental methods and the development of complex models to analyze the data. Focusing on methods that are being used to solve current problems in biomedical science and engineering, this comprehensive, richly illustrated resource shows you how to design of state-of-the art methods for analyzing biological systems, implement experimental approaches for investigating cellular behavior in health and disease, use algorithms and modeling techniques for quantitatively describing biomedical

  14. Methods in mummy research

    Lynnerup, Niels


    Mummies are human remains with preservation of non-bony tissue. Many mummy studies focus on the development and application of non-destructive methods for examining mummies, including radiography, CT-scanning with advanced 3-dimensional visualisations, and endoscopic techniques, as well as minima......Mummies are human remains with preservation of non-bony tissue. Many mummy studies focus on the development and application of non-destructive methods for examining mummies, including radiography, CT-scanning with advanced 3-dimensional visualisations, and endoscopic techniques, as well...... as minimally-destructive chemical, physical and biological methods for, e.g., stable isotopes, trace metals and DNA....

  15. The Prescribed Velocity Method

    Nielsen, Peter Vilhelm

    The- velocity level in a room ventilated by jet ventilation is strongly influenced by the supply conditions. The momentum flow in the supply jets controls the air movement in the room and, therefore, it is very important that the inlet conditions and the numerical method can generate a satisfactory...... description of this momentum flow. The Prescribed Velocity Method is a practical method for the description of an Air Terminal Device which will save grid points close to the opening and ensure the right level of the momentum flow....

  16. Montessori Method and ICTs

    Athanasios Drigas


    Full Text Available This article bridges the gap between the Montessori Method and Information and Communication Technologies (ICTs in contemporary education. It reviews recent research works which recall the Montessori philosophy, principles and didactical tools applying to today’s computers and supporting technologies in children’s learning process. This article reviews how important the stimulation of human senses in the learning process is, as well as the development of Montessori materials using the body and the hand in particular, all according to the Montessori Method along with recent researches over ICTs. Montessori Method within information society age acquires new perspectives, new functionality and new efficacy.

  17. Modern diffraction methods

    Mittemeijer, E J


    The role of diffraction methods for the solid-state sciences has been pivotal to determining the (micro)structure of a material. Particularly, the expanding activities in materials science have led to the development of new methods for analysis by diffraction. This book offers an authoritative overview of the new developments in the field of analysis of matter by (in particular X-ray, electron and neutron) diffraction. It is composed of chapters written by leading experts on 'modern diffraction methods'. The focus in the various chapters of this book is on the current forefront of research on

  18. Numerical methods using Matlab

    Lindfield, George


    Numerical Methods using MATLAB, 3e, is an extensive reference offering hundreds of useful and important numerical algorithms that can be implemented into MATLAB for a graphical interpretation to help researchers analyze a particular outcome. Many worked examples are given together with exercises and solutions to illustrate how numerical methods can be used to study problems that have applications in the biosciences, chaos, optimization, engineering and science across the board. Numerical Methods using MATLAB, 3e, is an extensive reference offering hundreds of use

  19. Generalized subspace correction methods

    Kolm, P. [Royal Institute of Technology, Stockholm (Sweden); Arbenz, P.; Gander, W. [Eidgenoessiche Technische Hochschule, Zuerich (Switzerland)


    A fundamental problem in scientific computing is the solution of large sparse systems of linear equations. Often these systems arise from the discretization of differential equations by finite difference, finite volume or finite element methods. Iterative methods exploiting these sparse structures have proven to be very effective on conventional computers for a wide area of applications. Due to the rapid development and increasing demand for the large computing powers of parallel computers, it has become important to design iterative methods specialized for these new architectures.

  20. Methods for euclidean geometry

    Byer, Owen; Smeltzer, Deirdre L


    Euclidean plane geometry is one of the oldest and most beautiful topics in mathematics. Instead of carefully building geometries from axiom sets, this book uses a wealth of methods to solve problems in Euclidean geometry. Many of these methods arose where existing techniques proved inadequate. In several cases, the new ideas used in solving specific problems later developed into independent areas of mathematics. This book is primarily a geometry textbook, but studying geometry in this way will also develop students' appreciation of the subject and of mathematics as a whole. For instance, despite the fact that the analytic method has been part of mathematics for four centuries, it is rarely a tool a student considers using when faced with a geometry problem. Methods for Euclidean Geometry explores the application of a broad range of mathematical topics to the solution of Euclidean problems.

  1. Fashion, Mediations & Method Assemblages

    Sommerlund, Julie; Jespersen, Astrid Pernille

    of handling multiple, fluid realities with multiple, fluid methods. Empirically, the paper works with mediation in fashion - that is efforts the active shaping of relations between producer and consumer through communication, marketing and PR. Fashion mediation is by no means simple, but organise complex...... Modern. New York, Harvester-Wheatsheaf. Law, J. (2004). After Method - mess in social science research. London and New York, Routledge......., it is an important ambition of this paper to go into a methodological discussion of how "that which effectively happens" can be approached. To this end, the paper will combine Hennion's term of the "mediator" with John Laws methodological term of "method assemblages". Method assemblages is a suggested as a way...

  2. Iii. Sleep assessment methods.

    Sadeh, Avi


    Sleep is a complex phenomenon that could be understood and assessed at many levels. Sleep could be described at the behavioral level (relative lack of movements and awareness and responsiveness) and at the brain level (based on EEG activity). Sleep could be characterized by its duration, by its distribution during the 24-hr day period, and by its quality (e.g., consolidated versus fragmented). Different methods have been developed to assess various aspects of sleep. This chapter covers the most established and common methods used to assess sleep in infants and children. These methods include polysomnography, videosomnography, actigraphy, direct observations, sleep diaries, and questionnaires. The advantages and disadvantages of each method are highlighted.

  3. Methods in Modern Biophysics

    Nölting, Bengt


    Incorporating recent dramatic advances, this textbook presents a fresh and timely introduction to modern biophysical methods. An array of new, faster and higher-power biophysical methods now enables scientists to examine the mysteries of life at a molecular level. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, proteomics, and protein folding and structure. Incorporating much information previously unavailable in tutorial form, Nölting employs worked examples and about 270 illustrations to fully detail the techniques and their underlying mechanisms. Methods in Modern Biophysics is written for advanced undergraduate and graduate students, postdocs, researchers, lecturers, and professors in biophysics, biochemistry and related fields. Special features in the 3rd edition: Introduces rapid partial protein ladder sequencing - an important...

  4. Compressive Spectral Renormalization Method

    Bayindir, Cihan


    In this paper a novel numerical scheme for finding the sparse self-localized states of a nonlinear system of equations with missing spectral data is introduced. As in the Petviashivili's and the spectral renormalization method, the governing equation is transformed into Fourier domain, but the iterations are performed for far fewer number of spectral components (M) than classical versions of the these methods with higher number of spectral components (N). After the converge criteria is achieved for M components, N component signal is reconstructed from M components by using the l1 minimization technique of the compressive sampling. This method can be named as compressive spectral renormalization (CSRM) method. The main advantage of the CSRM is that, it is capable of finding the sparse self-localized states of the evolution equation(s) with many spectral data missing.

  5. Adaptive Algebraic Multigrid Methods

    Brezina, M; Falgout, R; MacLachlan, S; Manteuffel, T; McCormick, S; Ruge, J


    Our ability to simulate physical processes numerically is constrained by our ability to solve the resulting linear systems, prompting substantial research into the development of multiscale iterative methods capable of solving these linear systems with an optimal amount of effort. Overcoming the limitations of geometric multigrid methods to simple geometries and differential equations, algebraic multigrid methods construct the multigrid hierarchy based only on the given matrix. While this allows for efficient black-box solution of the linear systems associated with discretizations of many elliptic differential equations, it also results in a lack of robustness due to assumptions made on the near-null spaces of these matrices. This paper introduces an extension to algebraic multigrid methods that removes the need to make such assumptions by utilizing an adaptive process. The principles which guide the adaptivity are highlighted, as well as their application to algebraic multigrid solution of certain symmetric positive-definite linear systems.

  6. Ensemble Data Mining Methods

    Oza, Nikunj C.


    Ensemble Data Mining Methods, also known as Committee Methods or Model Combiners, are machine learning methods that leverage the power of multiple models to achieve better prediction accuracy than any of the individual models could on their own. The basic goal when designing an ensemble is the same as when establishing a committee of people: each member of the committee should be as competent as possible, but the members should be complementary to one another. If the members are not complementary, Le., if they always agree, then the committee is unnecessary---any one member is sufficient. If the members are complementary, then when one or a few members make an error, the probability is high that the remaining members can correct this error. Research in ensemble methods has largely revolved around designing ensembles consisting of competent yet complementary models.

  7. Concrete compositions and methods

    Chen, Irvin; Lee, Patricia Tung; Patterson, Joshua


    Provided herein are compositions, methods, and systems for cementitious compositions containing calcium carbonate compositions and aggregate. The compositions find use in a variety of applications, including use in a variety of building materials and building applications.

  8. Method of treating depression

    Henn, Fritz


    Methods for treatment of depression-related mood disorders in mammals, particularly humans are disclosed. The methods of the invention include administration of compounds capable of enhancing glutamate transporter activity in the brain of mammals suffering from depression. ATP-sensitive K.sup.+ channel openers and .beta.-lactam antibiotics are used to enhance glutamate transport and to treat depression-related mood disorders and depressive symptoms.

  9. On Danish Legal Method

    Schaumburg-Müller, Sten


    On the basis on 1) the Danish legal writer A.S.Ørsted (1778-1860) and 2) an enquete among present day Danish legal scholars, the contribution deals with special traits in Danish legal method......On the basis on 1) the Danish legal writer A.S.Ørsted (1778-1860) and 2) an enquete among present day Danish legal scholars, the contribution deals with special traits in Danish legal method...

  10. Method of treating depression

    Henn, Fritz [East Patchogue, NY


    Methods for treatment of depression-related mood disorders in mammals, particularly humans are disclosed. The methods of the invention include administration of compounds capable of enhancing glutamate transporter activity in the brain of mammals suffering from depression. ATP-sensitive K.sup.+ channel openers and .beta.-lactam antibiotics are used to enhance glutamate transport and to treat depression-related mood disorders and depressive symptoms.

  11. Bidirectional beam propagation method

    Kaczmarski, P.; Lagasse, P. E.


    A bidirectional extension of the beam propagation method (BPM) to optical waveguides with a longitudinal discontinuity is presented. The algorithm is verified by computing a reflection of the TE(0) mode from a semiconductor laser facet. The bidirectional BPM is applicable to other configurations such as totally reflecting waveguide mirrors, an abruption transition in a waveguide, or a waveguide with many discontinuities generating multiple reflections. The method can also be adapted to TM polarization.

  12. Monte Carlo methods

    Bardenet, R.


    ISBN:978-2-7598-1032-1; International audience; Bayesian inference often requires integrating some function with respect to a posterior distribution. Monte Carlo methods are sampling algorithms that allow to compute these integrals numerically when they are not analytically tractable. We review here the basic principles and the most common Monte Carlo algorithms, among which rejection sampling, importance sampling and Monte Carlo Markov chain (MCMC) methods. We give intuition on the theoretic...

  13. Methods for polymer synthesis

    Allen, Scott D.; Simoneau, Christopher A.; Keefe, William D.; Conuel, Jeff R.


    The present invention provides methods for reducing induction periods in epoxide-CO.sub.2 copolymerizations. In certain embodiments, the methods include the step of contacting an epoxide with CO.sub.2 in the presence of two catalysts: an epoxide hydrolysis catalyst and an epoxide CO.sub.2 copolymerization catalyst. In another aspect, the invention provides catalyst compositions comprising a mixture of an epoxide hydrolysis catalyst and an epoxide CO.sub.2 copolymerization catalyst.

  14. Painful Bile Extraction Methods


    It was only in the past 20 years that countries in Asia began to search for an alternative to protect moon bears from being killed for their bile and other body parts. In the early 1980s, a new method of extracting bile from living bears was developed in North Korea. In 1983, Chinese scientists imported this technique from North Korea. According to the Animals Asia Foundation, the most original method of bile extraction is to embed a latex catheter, a narrow rubber

  15. Multicriteria identification sets method

    Kamenev, G. K.


    A multicriteria identification and prediction method for mathematical models of simulation type in the case of several identification criteria (error functions) is proposed. The necessity of the multicriteria formulation arises, for example, when one needs to take into account errors of completely different origins (not reducible to a single characteristic) or when there is no information on the class of noise in the data to be analyzed. An identification sets method is described based on the approximation and visualization of the multidimensional graph of the identification error function and sets of suboptimal parameters. This method allows for additional advantages of the multicriteria approach, namely, the construction and visual analysis of the frontier and the effective identification set (frontier and the Pareto set for identification criteria), various representations of the sets of Pareto effective and subeffective parameter combinations, and the corresponding predictive trajectory tubes. The approximation is based on the deep holes method, which yields metric ɛ-coverings with nearly optimal properties, and on multiphase approximation methods for the Edgeworth-Pareto hull. The visualization relies on the approach of interactive decision maps. With the use of the multicriteria method, multiple-choice solutions of identification and prediction problems can be produced and justified by analyzing the stability of the optimal solution not only with respect to the parameters (robustness with respect to data) but also with respect to the chosen set of identification criteria (robustness with respect to the given collection of functionals).

  16. [Unproven methods in oncology].

    Jallut, O; Guex, P; Barrelet, L


    As in some other chronic diseases (rheumatism, multiple sclerosis, etc.), unproven methods of diagnosis and treatment have long been current in cancer. Since 1960 the American Cancer Society has published an abundant literature on these "unproven methods", which serves as a basis for a historical review: some substances (Krebiozen, Laetrile) have enjoyed tremendous if shortlived success. The present trend is back to nature and "mild medicine". The proponents of this so-called natural medicine are often disciples of a pseudoscientific religion using irrational arguments. Direct attacks on these erroneous theories and their public refutation fail to convince the adepts, who trust in these methods and are not amenable to a scientific approach. Study of their psychological motivations reveals that in fact they seek something more reassuring than plain medical explanation which is aware of its limits. They feel reassured by theories which often bear some resemblance to the old popular medicine. To protect patients against these dangerous methods and all the disillusionment they entail, the Swiss Society of Oncology and the Swiss Cancer League have decided to gather information and draw up a descriptive list of the commonest unproven methods in Switzerland (our File No. 2, "Total anti-cancer cure", is given as an example). The files are published in French, German and English and are available to physicians, nursing teams, and also patients who wish to have more objective information on these methods.

  17. [Barrier methods of contraception].

    Goldsmith, A; Edelman, D A


    Vaginal methods of contraception were the earliest types used and some references to them date back to antiquity. Most of the vaginal contraceptive agents identified by the ancient Greeks, Indians, Japanese, and Chinese have been found in modern laboratory tests to have spermicidal properties, but it is doubtful that the methods were fully reliable or were used by many people. During the 19th century the condom, vaginal spermicides, and diaphragm became available. The development of nonoxynol-9 and other nonirritating but effective spermicidal agents improved vaginal contraceptives greatly by the 1950s, but starting in the 1960s newer methods began to replace the vaginal methods. Interest in barrier methods has been reawakened somewhat by concern about the health effects of hormonal methods. At present all barrier methods leave something to be desired. Failure rates of 3-30% for barrier methods in general have been estimated, but the higher rates are believed due to incorrect or inconsistent use. Theoretical failure rates of condoms and diaphragms have been estimated at 3/100 women-years, but in actual use failure rates may reach 15 for condoms and 13 for diaphragms used with spermicides. Use-effectiveness rates are greatly influenced by motivation. For a variety of reasons, the acceptability of barrier methods is low, especially in developing countries. New developments in spermicidal agents include sperm inhibitors, which impede the fertilizing capacity of sperm rather than attempting a spermicidal effect; a number of such agents have been studied and have proven more effective in animal tests than conventional spermicides. Neosampoon, a new spermicidal foam, has attracted an increasing number of users, especially in developing countries. A new condom, made of thin polymers and containing a standard dose of nonoxynol-9, has been designed to dissolve in the vaginal fluid. Further studies are needed of its acceptability, efficacy, and side effects before it becomes

  18. The lod score method.

    Rice, J P; Saccone, N L; Corbett, J


    The lod score method originated in a seminal article by Newton Morton in 1955. The method is broadly concerned with issues of power and the posterior probability of linkage, ensuring that a reported linkage has a high probability of being a true linkage. In addition, the method is sequential, so that pedigrees or lod curves may be combined from published reports to pool data for analysis. This approach has been remarkably successful for 50 years in identifying disease genes for Mendelian disorders. After discussing these issues, we consider the situation for complex disorders, where the maximum lod score (MLS) statistic shares some of the advantages of the traditional lod score approach but is limited by unknown power and the lack of sharing of the primary data needed to optimally combine analytic results. We may still learn from the lod score method as we explore new methods in molecular biology and genetic analysis to utilize the complete human DNA sequence and the cataloging of all human genes.

  19. New oligosaccharyltransferase assay method.

    Kohda, Daisuke; Yamada, Masaki; Igura, Mayumi; Kamishikiryo, Jun; Maenaka, Katsumi


    We developed a new in vitro assay for oligosaccharyltransferase (OST), which catalyzes the transfer of preassembled oligosaccharides on lipid carriers onto asparagine residues in polypeptide chains. The asparagine residues reside in the sequon, Asn-X-Thr/Ser, where X can be any amino acid residue except Pro. We demonstrate the potency of our assay using the OST from yeast. In our method, polyacrylamide gel electrophoresis is used to separate the glycopeptide products from the peptide substrates. The substrate peptide is fluorescently labeled and the formation of glycopeptides is analyzed by fluorescence gel imaging. Two in vitro OST assay methods are now widely used, but both the methods depend on previous knowledge of the oligosaccharide moiety: One method uses lectin binding as the separation mechanism and the other method uses biosynthetically or chemoenzymatically synthesized lipid-linked oligosaccharides as donors. N-linked protein glycosylation is found in all three domains of life, but little is known about the N-glycosylation in Archaea. Thus, our new assay, which does not require a priori knowledge of the oligosaccharides, will be useful in such cases. Indeed, we have detected the OST activity in the membrane fraction from a hyperthermophilic archaeon, Pyrococcus furiosus.

  20. Methods for Neutron Spectrometry

    Brockhouse, Bertram N.


    The appropriate theories and the general philosophy of methods of measurement and treatment of data neutron spectrometry are discussed. Methods of analysis of results for liquids using the Van Hove formulation, and for crystals using the Born-von Karman theory, are reviewed. The most useful of the available methods of measurement are considered to be the crystal spectrometer methods and the pulsed monoenergetic beam/time-of-flight method. Pulsed-beam spectrometers have the advantage of higher counting rates than crystal spectrometers, especially in view of the fact that simultaneous measurements in several counters at different angles of scattering are possible in pulsed-beam spectrometers. The crystal spectrometer permits several valuable new types of specialized experiments to be performed, especially energy distribution measurements at constant momentum transfer. The Chalk River triple-axis crystal-spectrometer is discussed, with reference to its use in making the specialized experiments. The Chalk River rotating crystal (pulsed-beam) spectrometer is described, and a comparison of this type instrument with other pulsed-beam spectrometers is made. A partial outline of the theory of operation of rotating-crystal spectrometers is presented. The use of quartz-crystal filters for fast neutron elimination and for order elimination is discussed. (auth)

  1. Method of treating wells

    Knox, J.A.; Lasater, R.M.


    Chemical compositions and methods are provided for treating underground formations to render their surfaces water-repellent or preferentially oil-wettable. Previous methods have provided only temporary water-repellency because they do not actually act chemically with the reservoir rock. This improvement is obtained by using a treating agent which does not form a precipitate upon hydrolysis with water, such as a liquid organo-halogen- silane or its ester. A water-soluble anhydrous solvent which is nonreactive with the silane is used as a carrier. This method may be used for treating non-oil-bearing aquifers for increasing the flow rate of water, such as in water supply wells, or in water input rate, such as in water disposal wells. (10 claims)

  2. Geostatistical Methods in R

    Adéla Volfová


    Full Text Available Geostatistics is a scientific field which provides methods for processing spatial data.  In our project, geostatistics is used as a tool for describing spatial continuity and making predictions of some natural phenomena. An open source statistical project called R is used for all calculations. Listeners will be provided with a brief introduction to R and its geostatistical packages and basic principles of kriging and cokriging methods. Heavy mathematical background is omitted due to its complexity. In the second part of the presentation, several examples are shown of how to make a prediction in the whole area of interest where observations were made in just a few points. Results of these methods are compared.

  3. Model Correction Factor Method

    Christensen, Claus; Randrup-Thomsen, Søren; Morsing Johannesen, Johannes


    The model correction factor method is proposed as an alternative to traditional polynomial based response surface techniques in structural reliability considering a computationally time consuming limit state procedure as a 'black box'. The class of polynomial functions is replaced by a limit...... statebased on an idealized mechanical model to be adapted to the original limit state by the model correction factor. Reliable approximations are obtained by iterative use of gradient information on the original limit state function analogously to previous response surface approaches. However, the strength...... of the model correction factor method, is that in simpler form not using gradient information on the original limit state function or only using this information once, a drastic reduction of the number of limit state evaluation is obtained together with good approximations on the reliability. Methods...

  4. Sampling system and method

    Decker, David L.; Lyles, Brad F.; Purcell, Richard G.; Hershey, Ronald Lee


    In one embodiment, the present disclosure provides an apparatus and method for supporting a tubing bundle during installation or removal. The apparatus includes a clamp for securing the tubing bundle to an external wireline. In various examples, the clamp is external to the tubing bundle or integral with the tubing bundle. According to one method, a tubing bundle and wireline are deployed together and the tubing bundle periodically secured to the wireline using a clamp. In another embodiment, the present disclosure provides an apparatus and method for coupling conduit segments together. A first pump obtains a sample and transmits it through a first conduit to a reservoir accessible by a second pump. The second pump further conducts the sample from the reservoir through a second conduit. In a specific example, one or more clamps are used to connect the first and/or second conduits to an external wireline.

  5. Robust iterative methods

    Saadd, Y.


    In spite of the tremendous progress achieved in recent years in the general area of iterative solution techniques, there are still a few obstacles to the acceptance of iterative methods in a number of applications. These applications give rise to very indefinite or highly ill-conditioned non Hermitian matrices. Trying to solve these systems with the simple-minded standard preconditioned Krylov subspace methods can be a frustrating experience. With the mathematical and physical models becoming more sophisticated, the typical linear systems which we encounter today are far more difficult to solve than those of just a few years ago. This trend is likely to accentuate. This workshop will discuss (1) these applications and the types of problems that they give rise to; and (2) recent progress in solving these problems with iterative methods. The workshop will end with a hopefully stimulating panel discussion with the speakers.

  6. Cytoskeleton - Methods and Protocols

    CarloAlberto Redi


    Full Text Available Cytoskeleton - Methods and ProtocolsSecond edition, 2010; Ray H. Gavin (Ed; Springer Protocols methods in molecular biology, vol. 586 Humana press, Totowa, New Jersey (USA; Pages: 390; €95.44; ISBN: 978-1-60761-375-6Ray H. Gavin, from the Brooklyn College of The City University of New York, Brooklyn, NY, USA, wrote a few line as preface of this book. This is quite understandable: there is not a great need of words when there are facts that sustain and favour the dissemination of a cultural product. This is the case of the second edition of Cytoskeleton - Methods and Protocols, which appears just ten years after the first edition...

  7. The impact of donor-specific anti-HLA antibodies on late kidney allograft failure.

    Loupy, Alexandre; Hill, Gary S; Jordan, Stanley C


    Despite improvements in outcomes of renal transplantation, kidney allograft loss remains substantial, and is associated with increased morbidity, mortality and costs. Identifying the pathologic pathways responsible for allograft loss, and the attendant development of therapeutic interventions, will be one of the guiding future objectives of transplant medicine. One of the most important advances of the past decade has been the demonstration of the destructive power of anti-HLA alloantibodies and their association with antibody-mediated rejection (ABMR). Compelling evidence exists to show that donor-specific anti-HLA antibodies (DSAs) are largely responsible for the chronic deterioration of allografts, a condition previously attributed to calcineurin inhibitor toxicity and chronic allograft nephropathy. The emergence of sensitive techniques to detect DSAs, together with advances in the assessment of graft pathology, have expanded the spectrum of what constitutes ABMR. Today, subtler forms of rejection--such as indolent ABMR, C4d-negative ABMR, and transplant arteriopathy--are seen in which DSAs exert a marked pathological effect. In addition, arteriosclerosis, previously thought to be a bystander lesion related to the vicissitudes of aging, is accelerated in ABMR. Advances in our understanding of the pathological significance of DSAs and ABMR show their primacy in the mediation of chronic allograft destruction. Therapies aimed at B cells, plasma cells and antibodies will be important therapeutic options to improve the length and quality of kidney allograft survival.

  8. Nonparametric statistical methods

    Hollander, Myles; Chicken, Eric


    Praise for the Second Edition"This book should be an essential part of the personal library of every practicing statistician."-Technometrics  Thoroughly revised and updated, the new edition of Nonparametric Statistical Methods includes additional modern topics and procedures, more practical data sets, and new problems from real-life situations. The book continues to emphasize the importance of nonparametric methods as a significant branch of modern statistics and equips readers with the conceptual and technical skills necessary to select and apply the appropriate procedures for any given sit

  9. Practical methods of optimization

    Fletcher, R


    Fully describes optimization methods that are currently most valuable in solving real-life problems. Since optimization has applications in almost every branch of science and technology, the text emphasizes their practical aspects in conjunction with the heuristics useful in making them perform more reliably and efficiently. To this end, it presents comparative numerical studies to give readers a feel for possibile applications and to illustrate the problems in assessing evidence. Also provides theoretical background which provides insights into how methods are derived. This edition offers rev

  10. Method through motion

    Steijn, Arthur


    Contemporary scenography often consists of video-projected motion graphics. The field is lacking in academic methods and rigour: descriptions and models relevant for the creation as well as in the analysis of existing works. In order to understand the phenomenon of motion graphics in a scenographic...... construction as a support to working systematically practice-led research project. The design model is being developed through design laboratories and workshops with students and professionals who provide feedback that lead to incremental improvements. Working with this model construction-as-method reveals...

  11. Unorthodox theoretical methods

    Nedd, Sean [Iowa State Univ., Ames, IA (United States)


    The use of the ReaxFF force field to correlate with NMR mobilities of amine catalytic substituents on a mesoporous silica nanosphere surface is considered. The interfacing of the ReaxFF force field within the Surface Integrated Molecular Orbital/Molecular Mechanics (SIMOMM) method, in order to replicate earlier SIMOMM published data and to compare with the ReaxFF data, is discussed. The development of a new correlation consistent Composite Approach (ccCA) is presented, which incorporates the completely renormalized coupled cluster method with singles, doubles and non-iterative triples corrections towards the determination of heats of formations and reaction pathways which contain biradical species.

  12. Tautomerism methods and theories

    Antonov, Liudmil


    Covering the gap between basic textbooks and over-specialized scientific publications, this is the first reference available to describe this interdisciplinary topic for PhD students and scientists starting in the field. The result is an introductory description providing suitable practical examples of the basic methods used to study tautomeric processes, as well as the theories describing the tautomerism and proton transfer phenomena. It also includes different spectroscopic methods for examining tautomerism, such as UV-VIs, time-resolved fluorescence spectroscopy, and NMR spectrosc

  13. Dynamic encryption method


    Disclosed is a method of transmitting a data set using encryption, wherein the method comprises the steps of: selecting a first encryption technique, wherein said first encryption technique comprises a first encryption algorithm for encrypting plain data into cipher data, and a first decryption...... algorithm for on provision of a specific key, decrypting cipher data and reproduce plain data; encrypting the first data package comprising plain data, using a first encryption program implementing the first encryption algorithm of said first encryption technique, creating a first encrypted data package...

  14. Essential numerical computer methods

    Johnson, Michael L


    The use of computers and computational methods has become ubiquitous in biological and biomedical research. During the last 2 decades most basic algorithms have not changed, but what has is the huge increase in computer speed and ease of use, along with the corresponding orders of magnitude decrease in cost. A general perception exists that the only applications of computers and computer methods in biological and biomedical research are either basic statistical analysis or the searching of DNA sequence data bases. While these are important applications they only scratch the surface

  15. Apoptosis - Methods and Protocols

    CarloAlberto Redi


    Full Text Available Apoptosis - Methods and ProtocolsSecond edition, 2009; Peter Erhardt and Ambrus Toth (Eds; Springer Protocols - Methods in molecular biology, vol. 559; Humana press, Totowa, New Jersey (USA; Pages: 400; €88.35; ISBN: 978-1-60327-016-8The editors rightly begin the preface telling us that: “The ability to detect and quantify apoptosis, to understand its biochemistry and to identify its regulatory genes and proteins is crucial to biomedical research”. Nowadays this is a grounding concept of biology and medicine. What is particularly remarkable...


    Smith, C.S.


    A method is described for rolling uranium metal at relatively low temperatures and under non-oxidizing conditions. The method involves the steps of heating the uranium to 200 deg C in an oil bath, withdrawing the uranium and permitting the oil to drain so that only a thin protective coating remains and rolling the oil coated uranium at a temperature of 200 deg C to give about a 15% reduction in thickness at each pass. The operation may be repeated to accomplish about a 90% reduction without edge cracking, checking or any appreciable increase in brittleness.

  17. Methods of Multivariate Analysis

    Rencher, Alvin C


    Praise for the Second Edition "This book is a systematic, well-written, well-organized text on multivariate analysis packed with intuition and insight . . . There is much practical wisdom in this book that is hard to find elsewhere."-IIE Transactions Filled with new and timely content, Methods of Multivariate Analysis, Third Edition provides examples and exercises based on more than sixty real data sets from a wide variety of scientific fields. It takes a "methods" approach to the subject, placing an emphasis on how students and practitioners can employ multivariate analysis in real-life sit

  18. Electrorheological fluids and methods

    Green, Peter F.; McIntyre, Ernest C.


    Electrorheological fluids and methods include changes in liquid-like materials that can flow like milk and subsequently form solid-like structures under applied electric fields; e.g., about 1 kV/mm. Such fluids can be used in various ways as smart suspensions, including uses in automotive, defense, and civil engineering applications. Electrorheological fluids and methods include one or more polar molecule substituted polyhedral silsesquioxanes (e.g., sulfonated polyhedral silsesquioxanes) and one or more oils (e.g., silicone oil), where the fluid can be subjected to an electric field.

  19. Exploring Monte Carlo methods

    Dunn, William L


    Exploring Monte Carlo Methods is a basic text that describes the numerical methods that have come to be known as "Monte Carlo." The book treats the subject generically through the first eight chapters and, thus, should be of use to anyone who wants to learn to use Monte Carlo. The next two chapters focus on applications in nuclear engineering, which are illustrative of uses in other fields. Five appendices are included, which provide useful information on probability distributions, general-purpose Monte Carlo codes for radiation transport, and other matters. The famous "Buffon's needle proble

  20. Splines and variational methods

    Prenter, P M


    One of the clearest available introductions to variational methods, this text requires only a minimal background in calculus and linear algebra. Its self-contained treatment explains the application of theoretic notions to the kinds of physical problems that engineers regularly encounter. The text's first half concerns approximation theoretic notions, exploring the theory and computation of one- and two-dimensional polynomial and other spline functions. Later chapters examine variational methods in the solution of operator equations, focusing on boundary value problems in one and two dimension

  1. Analogue computing methods

    Welbourne, D


    Analogue Computing Methods presents the field of analogue computation and simulation in a compact and convenient form, providing an outline of models and analogues that have been produced to solve physical problems for the engineer and how to use and program the electronic analogue computer. This book consists of six chapters. The first chapter provides an introduction to analogue computation and discusses certain mathematical techniques. The electronic equipment of an analogue computer is covered in Chapter 2, while its use to solve simple problems, including the method of scaling is elaborat

  2. Molecular methods for biofilms

    Ferrera, Isabel


    This chapter deals with both classical and modern molecular methods that can be useful for the identification of microorganisms, elucidation and comparison of microbial communities, and investigation of their diversity and functions. The most important and critical steps necessary for all molecular methods is DNA isolation from microbial communities and environmental samples; these are discussed in the first part. The second part provides an overview over DNA polymerase chain reaction (PCR) amplification and DNA sequencing methods. Protocols and analysis software as well as potential pitfalls associated with application of these methods are discussed. Community fingerprinting analyses that can be used to compare multiple microbial communities are discussed in the third part. This part focuses on Denaturing Gradient Gel Electrophoresis (DGGE), Terminal Restriction Fragment Length Polymorphism (T-RFLP) and Automated rRNA Intergenic Spacer Analysis (ARISA) methods. In addition, classical and next-generation metagenomics methods are presented. These are limited to bacterial artificial chromosome and Fosmid libraries and Sanger and next-generation 454 sequencing, as these methods are currently the most frequently used in research. Isolation of nucleic acids: This chapter discusses, the most important and critical steps necessary for all molecular methods is DNA isolation from microbial communities and environmental samples. Nucleic acid isolation methods generally include three steps: cell lysis, removal of unwanted substances, and a final step of DNA purification and recovery. The first critical step is the cell lysis, which can be achieved by enzymatic or mechanical procedures. Removal of proteins, polysaccharides and other unwanted substances is likewise important to avoid their interference in subsequent analyses. Phenol-chloroform-isoamyl alcohol is commonly used to recover DNA, since it separates nucleic acids into an aqueous phase and precipitates proteins and

  3. Method for forming ammonia

    Kong, Peter C.; Pink, Robert J.; Zuck, Larry D.


    A method for forming ammonia is disclosed and which includes the steps of forming a plasma; providing a source of metal particles, and supplying the metal particles to the plasma to form metal nitride particles; and providing a substance, and reacting the metal nitride particles with the substance to produce ammonia, and an oxide byproduct.

  4. A method for sintering


    The present invention provides a method for sintering, comprising in the following order the steps of: providing a body in the green state or in the pre-sintered state on a support; providing a load on at least one spacer on the support such that the load is located above said body in the green...

  5. Truth and Methods.

    Dasenbrock, Reed Way


    Examines literary theory's displacing of "method" in the New Historicist criticism. Argues that Stephen Greenblatt and Lee Paterson imply that no objective historical truth is possible and as a result do not give methodology its due weight in their criticism. Questions the theory of "truth" advanced in this vein of literary…

  6. Research Methods in Sociolinguistics

    Hernández-Campoy, Juan Manuel


    The development of Sociolinguistics has been qualitatively and quantitatively outstanding within Linguistic Science since its beginning in the 1950s, with a steady growth in both theoretical and methodological developments as well as in its interdisciplinary directions within the spectrum of language and society. Field methods in sociolinguistic…

  7. Photothermal methods in medicine

    Murphy, John C.


    Photothermal imaging and spectroscopy are being applied to a variety of medical problems for diagnosis and therapy. This paper reviews some aspects of this field including the opportunities presented by non-optical sources and by use of detection methods targeted to the application.

  8. Biomass treatment method

    Friend, Julie; Elander, Richard T.; Tucker, III; Melvin P.; Lyons, Robert C.


    A method for treating biomass was developed that uses an apparatus which moves a biomass and dilute aqueous ammonia mixture through reaction chambers without compaction. The apparatus moves the biomass using a non-compressing piston. The resulting treated biomass is saccharified to produce fermentable sugars.

  9. Sampling system and method

    Decker, David L.; Lyles, Brad F.; Purcell, Richard G.; Hershey, Ronald Lee


    The present disclosure provides an apparatus and method for coupling conduit segments together. A first pump obtains a sample and transmits it through a first conduit to a reservoir accessible by a second pump. The second pump further conducts the sample from the reservoir through a second conduit.

  10. Performative Schizoid Method

    Svabo, Connie


    method in Becoming Iris results in four audio-visual and performance-based productions, centered on an emergent theme of the scholartist as a bird in borrowed feathers. Interestingly, the moral lesson of the fable about the vain jackdaw, who dresses in borrowed peacock feathers and becomes a castout...

  11. Quality of regularization methods

    Bouwman, J.


    The solution of ill-posed problems is non-trivial in the sense that frequently applied methods like least-squares fail. The ill-posedness of the problem is refiected by very small changes in the input data which may result in very large changes in the output data. Hence, some sort of stabilization o

  12. Software specification methods

    Habrias, Henri


    This title provides a clear overview of the main methods, and has a practical focus that allows the reader to apply their knowledge to real-life situations. The following are just some of the techniques covered: UML, Z, TLA+, SAZ, B, OMT, VHDL, Estelle, SDL and LOTOS.

  13. The Effective Equation Method

    Kuksin, Sergei; Maiocchi, Alberto

    In this chapter we present a general method of constructing the effective equation which describes the behavior of small-amplitude solutions for a nonlinear PDE in finite volume, provided that the linear part of the equation is a hamiltonian system with a pure imaginary discrete spectrum. The effective equation is obtained by retaining only the resonant terms of the nonlinearity (which may be hamiltonian, or may be not); the assertion that it describes the limiting behavior of small-amplitude solutions is a rigorous mathematical theorem. In particular, the method applies to the three- and four-wave systems. We demonstrate that different possible types of energy transport are covered by this method, depending on whether the set of resonances splits into finite clusters (this happens, e.g. in case of the Charney-Hasegawa-Mima equation), or is connected (this happens, e.g. in the case of the NLS equation if the space-dimension is at least two). For equations of the first type the energy transition to high frequencies does not hold, while for equations of the second type it may take place. Our method applies to various weakly nonlinear wave systems, appearing in plasma, meteorology and oceanography.

  14. Modern Reduction Methods

    Andersson, Pher G


    With its comprehensive overview of modern reduction methods, this book features high quality contributions allowing readers to find reliable solutions quickly and easily. The monograph treats the reduction of carbonyles, alkenes, imines and alkynes, as well as reductive aminations and cross and heck couplings, before finishing off with sections on kinetic resolutions and hydrogenolysis. An indispensable lab companion for every chemist.

  15. Methods of materiality

    Aagaard, Jesper; Matthiesen, Noomi


    , and the method of participant observation is suggested as a viable approach to achieve this end. An empirical example of how authority is produced in a parent-teacher conference, not only through language but also through material objects and embodied being, is then presented. The article concludes by suggesting...

  16. Convergence of Arnoldi method

    Nevanlinna, O. [Helsinki Univ. of Technology, Espoo (Finland)


    This note summarizes some results on (a monitored version of) the Arnoldi method in Hilbert spaces. The interest in working in infinite dimensional spaces comes partly from the fact that only then can one have meaningful asymptotical statements (which hopefully give some light to the convergence of Arnoldi in large dimensional problems with iteration indices far less than the dimension).

  17. The Method of "Currere."

    Pinar, William Frederick

    In this presentation the author paints a conceptual portrait of his evolving relationships to his formal studies and thereby describes a method by which educators can reconceptualize the meaning of curriculum. By taking oneself and one's existential experience as a data source and using the psychoanalytical technique of free association, one can…

  18. Analysis of numerical methods

    Isaacson, Eugene


    This excellent text for advanced undergraduates and graduate students covers norms, numerical solution of linear systems and matrix factoring, iterative solutions of nonlinear equations, eigenvalues and eigenvectors, polynomial approximation, and other topics. It offers a careful analysis and stresses techniques for developing new methods, plus many examples and problems. 1966 edition.

  19. Ergonomics research methods

    Uspenskiy, S. I.; Yermakova, S. V.; Chaynova, L. D.; Mitkin, A. A.; Gushcheva, T. M.; Strelkov, Y. K.; Tsvetkova, N. F.


    Various factors used in ergonomic research are given. They are: (1) anthrometric measurement, (2) polyeffector method of assessing the functional state of man, (3) galvanic skin reaction, (4) pneumography, (5) electromyography, (6) electrooculography, and (7) tachestoscopy. A brief summary is given of each factor and includes instrumentation and results.

  20. Methods Evolved by Observation

    Montessori, Maria


    Montessori's idea of the child's nature and the teacher's perceptiveness begins with amazing simplicity, and when she speaks of "methods evolved," she is unveiling a methodological system for observation. She begins with the early childhood explosion into writing, which is a familiar child phenomenon that Montessori has written about…

  1. Progress in variational methods


    @@ The International Conference on Variational Methods (ICVAM) was held from May 20th to 26th in 2007 at the Chern Institute of Mathematics, Nankai University, Tianjin, China. Twenty eight invited speakers from ten countries and areas worldwide gave their lectures at the conference.

  2. communication method and apparatus


    The present invention relates to a non-lingual communication method and apparatus, wherein a physical or physiological signal consciously created by a first subject (1) is detected and converted into a transmitted output signal presented to a second subject (7) in order to communicate information...


    Cohen, K.


    A method of isotope separation is described in which two streams are flowed axially of, and countercurrently through, a cylindrical centrifuge bowl. Under the influence of a centrifugal field, the light fraction is concentrated in a stream flowing through the central portion of the bowl, whereas the heavy fraction is concentrated in a stream at the periphery thereof.

  4. Making Methods Choices.

    Patton, Michael Quinn


    Methodological paradigms in evaluation research are discussed. This article is a response to the attacks on paradigmatic perspectives made by Reichardt and Cook in the opening chapter of their edited book, "Qualitative and Quantitative Methods in Evaluation Research." (Author/GK)

  5. Photovoltaic device and method

    Cleereman, Robert; Lesniak, Michael J.; Keenihan, James R.; Langmaid, Joe A.; Gaston, Ryan; Eurich, Gerald K.; Boven, Michelle L.


    The present invention is premised upon an improved photovoltaic device ("PVD") and method of use, more particularly to an improved photovoltaic device with an integral locator and electrical terminal mechanism for transferring current to or from the improved photovoltaic device and the use as a system.

  6. Water-budget methods

    Healy, Richard W.; Scanlon, Bridget R.


    A water budget is an accounting of water movement into and out of, and storage change within, some control volume. Universal and adaptable are adjectives that reflect key features of water-budget methods for estimating recharge. The universal concept of mass conservation of water implies that water-budget methods are applicable over any space and time scales (Healy et al., 2007). The water budget of a soil column in a laboratory can be studied at scales of millimeters and seconds. A water-budget equation is also an integral component of atmospheric general circulation models used to predict global climates over periods of decades or more. Water-budget equations can be easily customized by adding or removing terms to accurately portray the peculiarities of any hydrologic system. The equations are generally not bound by assumptions on mechanisms by which water moves into, through, and out of the control volume of interest. So water-budget methods can be used to estimate both diffuse and focused recharge, and recharge estimates are unaffected by phenomena such as preferential flow paths within the unsaturated zone. Water-budget methods represent the largest class of techniques for estimating recharge. Most hydrologic models are derived from a water-budget equation and can therefore be classified as water-budget models. It is not feasible to address all water-budget methods in a single chapter. This chapter is limited to discussion of the “residual” water-budget approach, whereby all variables in a water-budget equation, except for recharge, are independently measured or estimated and recharge is set equal to the residual. This chapter is closely linked with Chapter 3, on modeling methods, because the equations presented here form the basis of many models and because models are often used to estimate individual components in water-budget studies. Water budgets for streams and other surface-water bodies are addressed in Chapter 4. The use of soil-water budgets and

  7. Nonhazardous Urine Pretreatment Method

    Akse, James R.; Holtsnider, John T.


    A method combines solid phase acidification with two non-toxic biocides to prevent ammonia volatilization and microbial proliferation. The safe, non-oxidizing biocide combination consists of a quaternary amine and a food preservative. This combination has exhibited excellent stabilization of both acidified and unacidified urine. During pretreatment tests, composite urine collected from donors was challenged with a microorganism known to proliferate in urine, and then was processed using the nonhazardous urine pre-treatment method. The challenge microorganisms included Escherichia coli, a common gram-negative bacteria; Enterococcus faecalis, a ureolytic gram-positive bacteria; Candida albicans, a yeast commonly found in urine; and Aspergillus niger, a problematic mold that resists urine pre-treatment. Urine processed in this manner remained microbially stable for over 57 days. Such effective urine stabilization was achieved using non-toxic, non-oxidizing biocides at higher pH (3.6 to 5.8) than previous methods in use or projected for use aboard the International Space Station (ISS). ISS urine pretreatment methods employ strong oxidants including ozone and hexavalent chromium (Cr(VI)), a carcinogenic material, under very acidic conditions (pH = 1.8 to 2.4). The method described here offers a much more benign chemical environment than previous pretreatment methods, and will lower equivalent system mass (ESM) by reducing containment volume and mass, system complexity, and crew time needed to handle pre-treatment chemicals. The biocides, being non-oxidizing, minimize the potential for chemical reactions with urine constituents to produce volatile, airborne contaminants such as cyanogen chloride. Additionally, the biocides are active under significantly less acidic conditions than those used in the current system, thereby reducing the degree of required acidification. A simple flow-through solid phase acidification (SPA) bed is employed to overcome the natural buffering


    Roxana L. IONESCU


    Full Text Available Companies operating in a global economy that is constantly changing and developming, especially during the financial crisis and political instability. It is necessary to adapt and develop sales methods in such environment. For large companies who base their activity on sales it has become a necessity to learn different types of sales approaches because their knowledge enables them to grow the number of customers and therefore the sales and the turnover. This paper aims to exame the most effective sales methods used on the highly sensitive economic and social environment – the insurance market. In the field of insurances, the sales process is even more important because sellers need to sell an intangible product that may materialize in the future, but there is no certainty.

  9. Nanoscale waveguiding methods.

    Wang, Chia-Jean; Lin, Lih Y


    While 32 nm lithography technology is on the horizon for integrated circuit (IC) fabrication, matching the pace for miniaturization with optics has been hampered by the diffraction limit. However, development of nanoscale components and guiding methods is burgeoning through advances in fabrication techniques and materials processing. As waveguiding presents the fundamental issue and cornerstone for ultra-high density photonic ICs, we examine the current state of methods in the field. Namely, plasmonic, metal slot and negative dielectric based waveguides as well as a few sub-micrometer techniques such as nanoribbons, high-index contrast and photonic crystals waveguides are investigated in terms of construction, transmission, and limitations. Furthermore, we discuss in detail quantum dot (QD) arrays as a gain-enabled and flexible means to transmit energy through straight paths and sharp bends. Modeling, fabrication and test results are provided and show that the QD waveguide may be effective as an alternate means to transfer light on sub-diffraction dimensions.

  10. Developments in Surrogating Methods

    Hans van Dormolen


    Full Text Available In this paper, I would like to talk about the developments in surrogating methods for preservation. My main focus will be on the technical aspects of preservation surrogates. This means that I will tell you something about my job as Quality Manager Microfilming for the Netherlands’ national preservation program, Metamorfoze, which is coordinated by the National Library. I am responsible for the quality of the preservation microfilms, which are produced for Metamorfoze. Firstly, I will elaborate on developments in preservation methods in relation to the following subjects: · Preservation microfilms · Scanning of preservation microfilms · Preservation scanning · Computer Output Microfilm. In the closing paragraphs of this paper, I would like to tell you something about the methylene blue test. This is an important test for long-term storage of preservation microfilms. Also, I will give you a brief report on the Cellulose Acetate Microfilm Conference that was held in the British Library in London, May 2005.

  11. Methods for forming particles

    Fox, Robert V.; Zhang, Fengyan; Rodriguez, Rene G.; Pak, Joshua J.; Sun, Chivin


    Single source precursors or pre-copolymers of single source precursors are subjected to microwave radiation to form particles of a I-III-VI.sub.2 material. Such particles may be formed in a wurtzite phase and may be converted to a chalcopyrite phase by, for example, exposure to heat. The particles in the wurtzite phase may have a substantially hexagonal shape that enables stacking into ordered layers. The particles in the wurtzite phase may be mixed with particles in the chalcopyrite phase (i.e., chalcopyrite nanoparticles) that may fill voids within the ordered layers of the particles in the wurtzite phase thus produce films with good coverage. In some embodiments, the methods are used to form layers of semiconductor materials comprising a I-III-VI.sub.2 material. Devices such as, for example, thin-film solar cells may be fabricated using such methods.

  12. by Lifting Line Method

    Horia Dumitrescu


    Full Text Available The vortex model of propellers is modified and applied to the high-speed horizontal axis turbines. The turbine blades are replaced by lifting lines and trailing vortices which shed along the blade span. The model is not a free wake model, but it is still a nonlinear one which should be solved iteratively. In addition to the regular case where the trailing vortices are constrained to distribute along a helical surface, another version, where each trailing vortex sheding from the blade grows as a free helical vortex line, is also included. Performance parameters are calculated by application of the Biot-Savart law along with the Kutta-Joukowski theorem. Predictions are, shown to compare favorably with existing numerical data from more involved free wake methods, but require less computational effort. Thereby, the present method may be a very useful tool for calculating the aerodynamic loads on horizontal-axis wind turbine blades.

  13. Glycoconjugates and methods

    Bertozzi, Carolyn C. (Albany, CA); Yarema, Kevin J. (Albany, CA); Mahal; Lara K. (Berkeley, CA)


    Methods for making the functionalized glycoconjugates include (a) contacting a cell with a first monosaccharide, and (b) incubating the cell under conditions whereby the cell (i) internalizes the first monosaccharide, (ii) biochemically processes the first monosaccharide into a second saccharide, (iii) conjugates the saccharide to a carrier to form a glycoconjugate, and (iv) extracellularly expresses the glycoconjugate to form an extracellular glycoconjugate comprising a selectively reactive functional group. Methods for forming products at a cell further comprise contacting the functional group of the extracellularly expressed glycoconjugate with an agent which selectively reacts with the functional group to form a product. Subject compositions include cyto-compatible monosaccharides comprising a nitrogen or ether linked functional group selectively reactive at a cell surface and compositions and cells comprising such saccharides.

  14. Motor degradation prediction methods

    Arnold, J.R.; Kelly, J.F.; Delzingaro, M.J.


    Motor Operated Valve (MOV) squirrel cage AC motor rotors are susceptible to degradation under certain conditions. Premature failure can result due to high humidity/temperature environments, high running load conditions, extended periods at locked rotor conditions (i.e. > 15 seconds) or exceeding the motor`s duty cycle by frequent starts or multiple valve stroking. Exposure to high heat and moisture due to packing leaks, pressure seal ring leakage or other causes can significantly accelerate the degradation. ComEd and Liberty Technologies have worked together to provide and validate a non-intrusive method using motor power diagnostics to evaluate MOV rotor condition and predict failure. These techniques have provided a quick, low radiation dose method to evaluate inaccessible motors, identify degradation and allow scheduled replacement of motors prior to catastrophic failures.

  15. The Montessori Method

    Cathleen Haskins


    Full Text Available Dr. Maria Montessori provided the world with a powerful philosophy and practice for the advancement of humanity: change how we educate children and we change the world. She understood two things very clearly: One, that we can build a better world, a more just and peaceful place, when we educate for the realization of the individual and collective human potential; and two, that the only way to create an educational system that will that will serve this end is to scrap the current system entirely and replace it with a completely new system. She gave us a system through which to accomplish that goal: The Montessori Method. The following is a personal and professional account of the Montessori Method of educating children.

  16. Method card design dimensions

    Wölfel, Christiane; Merritt, T.


    . The card-based tools are explained in terms of five design dimensions including the intended purpose and scope of use, duration of use, methodology, customization, and formal/material qualities. Our analysis suggests three design patterns or archetypes for existing card-based design method tools...... and highlights unexplored areas in the design space. The paper concludes with recommendations for the future development of card-based methods for the field of interaction design.......There are many examples of cards used to assist or provide structure to the design process, yet there has not been a thorough articulation of the strengths and weaknesses of the various examples. We review eighteen card-based design tools in order to understand how they might benefit designers...




    Full Text Available The effort in this work to elaborate an action research method as a central research problem considering the recent contemporary sociological and educa­tional literature. The author begins with the statement that the method is a complex notion, composed of three main components: approach to the research problem, data gathering procedures and data analysis procedures. This point of view is further applied and elaborated in the author's text, emphasizing the action research characteristics: interruption with the positive tradition in social research and the divided of the objective and subjective, application of the qualitative data. The sub­stantial difference between the action research in regard with the other kinds of research, is not only in getting to new knowledge's, but also in problem solving or a change in the situation in a concrete social context.

  18. in the DSMC Method

    Fong-Zhi Chen


    Full Text Available In this study, the Plücker coordinates representation is used to formulate the ruled surface and the molecular path for pumping speed performance evaluation of a molecular vacuum pump. The ruled surface represented by the Pliicker coordinates is used to develop a criterion for when gas molecules hit the pump surface wall. The criterion is applied to analyze the flow rate of a new developed vacuum pump in transition regimes by using the DSMC (Direct Simulation Monte Carlo method. When a molecule flies in a neutral electrical field its path is a straight line. If the molecular path and the generators of a ruled surface are both represented by the Pliicker coordinates, the position of the molecular hit on the wall can be verified by the reciprocal condition of the lines. The Plücker coordinates representation is quite convenient in the DSMC method for this three-dimensional molecular flow simulation.

  19. Die singulation method

    Swiler, Thomas P.; Garcia, Ernest J.; Francis, Kathryn M.


    A method is disclosed for singulating die from a semiconductor substrate (e.g. a semiconductor-on-insulator substrate or a bulk silicon substrate) containing an oxide layer (e.g. silicon dioxide or a silicate glass) and one or more semiconductor layers (e.g. monocrystalline or polycrystalline silicon) located above the oxide layer. The method etches trenches through the substrate and through each semiconductor layer about the die being singulated, with the trenches being offset from each other around at least a part of the die so that the oxide layer between the trenches holds the substrate and die together. The trenches can be anisotropically etched using a Deep Reactive Ion Etching (DRIE) process. After the trenches are etched, the oxide layer between the trenches can be etched away with an HF etchant to singulate the die. A release fixture can be located near one side of the substrate to receive the singulated die.

  20. Jet vortex methods

    Holm, Darryl D


    Vortex blob methods are typically characterized by a regularization length scale, below which the the dynamics are trivial for isolated blobs. In this article we will find that the dynamics need not be trivial if one is willing to consider distributional derivatives of Dirac delta functionals as valid vorticity distributions. More specifically, a new singular vortex theory is presented for regularised Euler fluid equations of ideal incompressible flow in the plane. We determine the conditions under which such regularised Euler fluid equations may admit vorticity singularities which are stronger than delta functions, e.g., derivatives of delta functions. We also characterise the Hamiltonian dynamics of the higher-order singular vortices. Applications to the design of numerical meth- ods similar to vortex blob methods are also discussed. Such findings shed light onto the rich dynamics which occur below the regularization length scale and enlighten our perspective on the multiscale aspects of regularized fluid m...

  1. Mitosis Methods & Protocols

    CarloAlberto Redi


    Full Text Available Mitosis Methods & Protocols Andrew D. McAinsh (Edt Humana press, Totowa, New Jersey (USA Series: Springer Protocols Methods in Molecular Biology, Volume 545, 2009 ISBN: 978-1-60327-992-5   It is quite clear from the contents of this book that the remarkably fascinating phenomenon of mitosis (that captured, and still is capturing, the attention of entire generations of scientists is still open to research. This is mainly due to our lack of knowledge of so many multifaced events of this extraordinarly complex process. The reader giving a glace through the Contents and Contributors sections is speechless: All of the first-class models (i.e., budding yeast, Caenorabditis, Drosophila, Xenopus and Human are presented..... 

  2. Statistical Methods for Astronomy

    Feigelson, Eric D


    This review outlines concepts of mathematical statistics, elements of probability theory, hypothesis tests and point estimation for use in the analysis of modern astronomical data. Least squares, maximum likelihood, and Bayesian approaches to statistical inference are treated. Resampling methods, particularly the bootstrap, provide valuable procedures when distributions functions of statistics are not known. Several approaches to model selection and good- ness of fit are considered. Applied statistics relevant to astronomical research are briefly discussed: nonparametric methods for use when little is known about the behavior of the astronomical populations or processes; data smoothing with kernel density estimation and nonparametric regression; unsupervised clustering and supervised classification procedures for multivariate problems; survival analysis for astronomical datasets with nondetections; time- and frequency-domain times series analysis for light curves; and spatial statistics to interpret the spati...

  3. Methods in Bioengineering

    Rege, Kaushal


    Filling a critical gap in the current literature, this new resource presents practical, step-by-step methods to help you synthesize, characterize, biofunctionalize and apply the nanomaterial that is most suitable for handling a given nanoscale bioengineering problem. Written and presented by leading scientists and engineers in their respective fields, the authors offer a clear and detailed understanding of how to carry out nanoparticle functionalization with biomolecules (including enzymes), nanoparticle analysis and characterization, in vitro evaluation of nanoparticles using different cell l

  4. Methods of celestial mechanics

    Brouwer, Dirk


    Methods of Celestial Mechanics provides a comprehensive background of celestial mechanics for practical applications. Celestial mechanics is the branch of astronomy that is devoted to the motions of celestial bodies. This book is composed of 17 chapters, and begins with the concept of elliptic motion and its expansion. The subsequent chapters are devoted to other aspects of celestial mechanics, including gravity, numerical integration of orbit, stellar aberration, lunar theory, and celestial coordinates. Considerable chapters explore the principles and application of various mathematical metho

  5. Method for detecting biomolecules

    Huo, Qisheng; Liu, Jun


    A method for detecting and measuring the concentration of biomolecules in solution, utilizing a conducting electrode in contact with a solution containing target biomolecules, with a film with controllable pore size distribution characteristics applied to at least one surface of the conducting electrode. The film is functionalized with probe molecules that chemically interact with the target biomolecules at the film surface, blocking indicator molecules present in solution from diffusing from the solution to the electrode, thereby changing the electrochemical response of the electrode

  6. Electron cryomicroscopy methods.

    Unger, V M


    Electron cryomicroscopy methods comprise a rapidly expanding field providing insights into the structure and function of biological macromolecules and their supramolecular assemblies. The 3.8 A resolution structure of the membrane protein aquaporin, a view of the herpesvirus capsid at 8.5 A and the 10 A resolution structure of the spliceosomal U1 small nuclear ribonucleoprotein complex are three outstanding examples emphasizing the versatility of this technique.

  7. Nearshore Pipeline Installation Methods.


    179. 5. Aldridge, R. G., and Bomba , J. G., "Deep Water Pipelines - Interdependence of Design and Construction", ASCE Paper. 6. American Society Civil...October 13, 1967. 24. Bomba , J. G. and Seeds, K. J., "Pipelining in 600 feet of water .... A Case Study of Washington Natural Gas Company’s Puget Sound...Crossing", Offshore Technology Conference, paper OTC 1188, 1970. 25. Bomba , J., "Submarine Pipe Construction Methods", Petroleum Engineer, Vol. 32

  8. Geometrical method of decoupling

    Baumgarten, C.


    The computation of tunes and matched beam distributions are essential steps in the analysis of circular accelerators. If certain symmetries—like midplane symmetry—are present, then it is possible to treat the betatron motion in the horizontal, the vertical plane, and (under certain circumstances) the longitudinal motion separately using the well-known Courant-Snyder theory, or to apply transformations that have been described previously as, for instance, the method of Teng and Edwards. In a preceding paper, it has been shown that this method requires a modification for the treatment of isochronous cyclotrons with non-negligible space charge forces. Unfortunately, the modification was numerically not as stable as desired and it was still unclear, if the extension would work for all conceivable cases. Hence, a systematic derivation of a more general treatment seemed advisable. In a second paper, the author suggested the use of real Dirac matrices as basic tools for coupled linear optics and gave a straightforward recipe to decouple positive definite Hamiltonians with imaginary eigenvalues. In this article this method is generalized and simplified in order to formulate a straightforward method to decouple Hamiltonian matrices with eigenvalues on the real and the imaginary axis. The decoupling of symplectic matrices which are exponentials of such Hamiltonian matrices can be deduced from this in a few steps. It is shown that this algebraic decoupling is closely related to a geometric “decoupling” by the orthogonalization of the vectors E→, B→, and P→, which were introduced with the so-called “electromechanical equivalence.” A mathematical analysis of the problem can be traced down to the task of finding a structure-preserving block diagonalization of symplectic or Hamiltonian matrices. Structure preservation means in this context that the (sequence of) transformations must be symplectic and hence canonical. When used iteratively, the decoupling


    Masrizal Masrizal


    Full Text Available Mixed Method Research adalah metode penelitian yang diaplikasikan bila peneliti memiliki pertanyaan yang perlu diuji dari segi outcomes dan prosesnya, serta menyangkut kombinasi antara metode kuantitatif dan kualitatif dalam satu penelitian. Karena berfokus pada outcomes dan proses, maka desain MMR biasa digunakan dalam penelitian evaluasi program. Namun sekarang, MMR sudah sering digunakan untuk ilmu-ilmu sosial, seperti: konseling, psikologi social manajemen, dan pengorganisasian perilaku.


    Masrizal Masrizal


    Mixed Method Research adalah metode penelitian yang diaplikasikan bila peneliti memiliki pertanyaan yang perlu diuji dari segi outcomes dan prosesnya, serta menyangkut kombinasi antara metode kuantitatif dan kualitatif dalam satu penelitian. Karena berfokus pada outcomes dan proses, maka desain MMR biasa digunakan dalam penelitian evaluasi program. Namun sekarang, MMR sudah sering digunakan untuk ilmu-ilmu sosial, seperti: konseling, psikologi social manajemen, dan pengorganisasian perilaku.

  11. Polymer compositions and methods

    Allen, Scott D.; Willkomm, Wayne R.


    The present invention encompasses polyurethane compositions comprising aliphatic polycarbonate chains. In one aspect, the present invention encompasses polyurethane foams, thermoplastics and elastomers derived from aliphatic polycarbonate polyols and polyisocyanates wherein the polyol chains contain a primary repeating unit having a structure: ##STR00001## In another aspect, the invention provides articles comprising the inventive foam and elastomer compositions as well as methods of making such compositions.

  12. Montessori Method and ICTs

    Athanasios Drigas; Eugenia Gkeka


    This article bridges the gap between the Montessori Method and Information and Communication Technologies (ICTs) in contemporary education. It reviews recent research works which recall the Montessori philosophy, principles and didactical tools applying to today’s computers and supporting technologies in children’s learning process. This article reviews how important the stimulation of human senses in the learning process is, as well as the development of Montessori materials using the body a...

  13. Methods in Bioengineering

    Zahn, Jeffrey D


    This unique volume presents leading-edge microfluidics methods used to handle, manipulate, and analyze cells, particles, and biological components (e.g., proteins and DNA) for microdiagnostics. The authors offer clear and detailed guidance on microfabrication techniques utilized to create microfluidic devices and on-chip flow control and mixing Microsystems, protein and DNA handling devices for electrophoretic and isoelectric separations in microchromatography columns, microfluidic manipulations of droplets via electrowetting and particles via dielectrophoresis for separations and chemical rea

  14. Chromosome doubling method

    Kato, Akio


    The invention provides methods for chromosome doubling in plants. The technique overcomes the low yields of doubled progeny associated with the use of prior techniques for doubling chromosomes in plants such as grasses. The technique can be used in large scale applications and has been demonstrated to be highly effective in maize. Following treatment in accordance with the invention, plants remain amenable to self fertilization, thereby allowing the efficient isolation of doubled progeny plants.

  15. Method of infusion extraction

    Chang-Diaz, Franklin R. (Inventor)


    Apparatus and method of removing desirable constituents from an infusible material by infusion extraction, where a piston operating in a first chamber draws a solvent into the first chamber where it may be heated, and then moves the heated solvent into a second chamber containing the infusible material, and where infusion extraction takes place. The piston then moves the solvent containing the extract through a filter into the first chamber, leaving the extraction residue in the second chamber.

  16. Situational method engineering

    Henderson-Sellers, Brian; Ågerfalk, Pär J; Rossi, Matti


    While previously available methodologies for software ? like those published in the early days of object technology ? claimed to be appropriate for every conceivable project, situational method engineering (SME) acknowledges that most projects typically have individual characteristics and situations. Thus, finding the most effective methodology for a particular project needs specific tailoring to that situation. Such a tailored software development methodology needs to take into account all the bits and pieces needed for an organization to develop software, including the software process, the

  17. Method for scavenging mercury

    Chang, Shih-ger; Liu, Shou-heng; Liu, Zhao-rong; Yan, Naiqiang


    Disclosed herein is a method for removing mercury from a gas stream comprising contacting the gas stream with a getter composition comprising bromine, bromochloride, sulphur bromide, sulphur dichloride or sulphur monochloride and mixtures thereof. In one preferred embodiment the getter composition is adsorbed onto a sorbent. The sorbent may be selected from the group consisting of flyash, limestone, lime, calcium sulphate, calcium sulfite, activated carbon, charcoal, silicate, alumina and mixtures thereof. Preferred is flyash, activated carbon and silica.

  18. Method for making nanomaterials

    Fan, Hongyou; Wu, Huimeng


    A method of making a nanostructure by preparing a face centered cubic-ordered metal nanoparticle film from metal nanoparticles, such as gold and silver nanoparticles, exerting a hydrostatic pressure upon the film at pressures of several gigapascals, followed by applying a non-hydrostatic stress perpendicularly at a pressure greater than approximately 10 GPA to form an array of nanowires with individual nanowires having a relatively uniform length, average diameter and density.

  19. Bering Mission Navigation Method


    "Bering", after the name of the famous Danish explorer, is a near Earth object (NEO) and main belt asteroids mapping mission envisaged by a consortium of Danish universities and research institutes. To achieve the ambitious goals set forth by this mission, while containing the costs and risks, "Bering" sports several new technological enhancements and advanced instruments under development at the Technical University of Denmark (DTU). The autonomous on-board orbit determination method is part...

  20. Generalized Agile Estimation Method

    Shilpa Bahlerao


    Full Text Available Agile cost estimation process always possesses research prospects due to lack of algorithmic approaches for estimating cost, size and duration. Existing algorithmic approach i.e. Constructive Agile Estimation Algorithm (CAEA is an iterative estimation method that incorporates various vital factors affecting the estimates of the project. This method has lots of advantages but at the same time has some limitations also. These limitations may due to some factors such as number of vital factors and uncertainty involved in agile projects etc. However, a generalized agile estimation may generate realistic estimates and eliminates the need of experts. In this paper, we have proposed iterative Generalized Estimation Method (GEM and presented algorithm based on it for agile with case studies. GEM  based algorithm various project domain classes and vital factors with prioritization level. Further, it incorporates uncertainty factor to quantify the risk of project for estimating cost, size and duration. It also provides flexibility to project managers for deciding on number of vital factors, uncertainty level and project domains thereby maintaining the agility.

  1. Validation of analytical methods

    Xavier Rius, F.


    Full Text Available In this paper we shall discuss the concept of method validation, describe the various elements and explain its close relationship with fitness for purpose. Method validation is based on the assumption that a series of requirements are fulfilled and we shall explain how these requirements are selected, the way in which evidence is supplied and what work has to be carried out in the laboratory. The basic principles of method validation and the different ways to validate a methodology, by inter-laboratory comparison or performing an in-house validation, are also described.En este artículo se discute el concepto de validación del método, se describen los elementos que la componen y se explica la fuerte relación entre la validación y las características de ajuste. El método de validación se basa en el cumplimiento de una serie de requerimientos, se explica como seleccionar esos requerimientos, la forma en que se suministran evidencias, y que trabajo se debe llevar a cabo en el laboratorio. También se describen, los principios básicos del método de validación y los diferentes caminos para validar una metodología, tanto en la comparación entre laboratorios o como cuando se lleva a cabo una validación dentro del laboratorio.

  2. Multigrid methods III

    Trottenberg, U; Third European Conference on Multigrid Methods


    These proceedings contain a selection of papers presented at the Third European Conference on Multigrid Methods which was held in Bonn on October 1-4, 1990. Following conferences in 1981 and 1985, a platform for the presentation of new Multigrid results was provided for a third time. Multigrid methods no longer have problems being accepted by numerical analysts and users of numerical methods; on the contrary, they have been further developed in such a successful way that they have penetrated a variety of new fields of application. The high number of 154 participants from 18 countries and 76 presented papers show the need to continue the series of the European Multigrid Conferences. The papers of this volume give a survey on the current Multigrid situation; in particular, they correspond to those fields where new developments can be observed. For example, se­ veral papers study the appropriate treatment of time dependent problems. Improvements can also be noticed in the Multigrid approach for semiconductor eq...

  3. Stochastic Methods in Biology

    Kallianpur, Gopinath; Hida, Takeyuki


    The use of probabilistic methods in the biological sciences has been so well established by now that mathematical biology is regarded by many as a distinct dis­ cipline with its own repertoire of techniques. The purpose of the Workshop on sto­ chastic methods in biology held at Nagoya University during the week of July 8-12, 1985, was to enable biologists and probabilists from Japan and the U. S. to discuss the latest developments in their respective fields and to exchange ideas on the ap­ plicability of the more recent developments in stochastic process theory to problems in biology. Eighteen papers were presented at the Workshop and have been grouped under the following headings: I. Population genetics (five papers) II. Measure valued diffusion processes related to population genetics (three papers) III. Neurophysiology (two papers) IV. Fluctuation in living cells (two papers) V. Mathematical methods related to other problems in biology, epidemiology, population dynamics, etc. (six papers) An important f...

  4. ARK methods: some recent developments

    Moir, Nicolette


    Almost Runge-Kutta methods are a sub-class of the family of methods known as general linear methods, used for solving ordinary differential equations. They combine many of the favourable properties of traditional Runge-Kutta methods with some additional advantages. We will introduce these methods, concentrating on methods of order four, and present some recent results.

  5. The data embedding method

    Sandford, M.T. II; Bradley, J.N.; Handel, T.G.


    Data embedding is a new steganographic method for combining digital information sets. This paper describes the data embedding method and gives examples of its application using software written in the C-programming language. Sandford and Handel produced a computer program (BMPEMBED, Ver. 1.51 written for IBM PC/AT or compatible, MS/DOS Ver. 3.3 or later) that implements data embedding in an application for digital imagery. Information is embedded into, and extracted from, Truecolor or color-pallet images in Microsoft{reg_sign} bitmap (.BMP) format. Hiding data in the noise component of a host, by means of an algorithm that modifies or replaces the noise bits, is termed {open_quote}steganography.{close_quote} Data embedding differs markedly from conventional steganography, because it uses the noise component of the host to insert information with few or no modifications to the host data values or their statistical properties. Consequently, the entropy of the host data is affected little by using data embedding to add information. The data embedding method applies to host data compressed with transform, or {open_quote}lossy{close_quote} compression algorithms, as for example ones based on discrete cosine transform and wavelet functions. Analysis of the host noise generates a key required for embedding and extracting the auxiliary data from the combined data. The key is stored easily in the combined data. Images without the key cannot be processed to extract the embedded information. To provide security for the embedded data, one can remove the key from the combined data and manage it separately. The image key can be encrypted and stored in the combined data or transmitted separately as a ciphertext much smaller in size than the embedded data. The key size is typically ten to one-hundred bytes, and it is in data an analysis algorithm.

  6. Data embedding method

    Sandford, Maxwell T., II; Bradley, Jonathan N.; Handel, Theodore G.


    Data embedding is a new steganographic method for combining digital information sets. This paper describes the data embedding method and gives examples of its application using software written in the C-programming language. Sandford and Handel produced a computer program (BMPEMBED, Ver. 1.51 written for IBM PC/AT or compatible, MS/DOS Ver. 3.3 or later) that implements data embedding in an application for digital imagery. Information is embedded into, and extracted from, Truecolor or color-pallet images in MicrosoftTM bitmap (BMP) format. Hiding data in the noise component of a host, by means of an algorithm that modifies or replaces the noise bits, is termed `steganography.' Data embedding differs markedly from conventional steganography, because it uses the noise component of the host to insert information with few or no modifications to the host data values or their statistical properties. Consequently, the entropy of the host data is affected little by using data embedding to add information. The data embedding method applies to host data compressed with transform, or `lossy' compression algorithms, as for example ones based on discrete cosine transform and wavelet functions. Analysis of the host noise generates a key required for embedding and extracting the auxiliary data from the combined data. The key is stored easily in the combined data. Images without the key cannot be processed to extract the embedded information. To provide security for the embedded data, one can remove the key from the combined data and manage it separately. The image key can be encrypted and stored in the combined data or transmitted separately as a ciphertext much smaller in size than the embedded data. The key size is typically ten to one-hundred bytes, and it is derived from the original host data by an analysis algorithm.

  7. Electrical estimating methods

    Del Pico, Wayne J


    Simplify the estimating process with the latest data, materials, and practices Electrical Estimating Methods, Fourth Edition is a comprehensive guide to estimating electrical costs, with data provided by leading construction database RS Means. The book covers the materials and processes encountered by the modern contractor, and provides all the information professionals need to make the most precise estimate. The fourth edition has been updated to reflect the changing materials, techniques, and practices in the field, and provides the most recent Means cost data available. The complexity of el

  8. Methods of graded rings

    Nastasescu, Constantin


    The topic of this book, graded algebra, has developed in the past decade to a vast subject with new applications in noncommutative geometry and physics. Classical aspects relating to group actions and gradings have been complemented by new insights stemming from Hopf algebra theory. Old and new methods are presented in full detail and in a self-contained way. Graduate students as well as researchers in algebra, geometry, will find in this book a useful toolbox. Exercises, with hints for solution, provide a direct link to recent research publications. The book is suitable for courses on Master level or textbook for seminars.

  9. Interior-point methods

    Potra, Florian A.; Wright, Stephen J.


    The modern era of interior-point methods dates to 1984, when Karmarkar proposed his algorithm for linear programming. In the years since then, algorithms and software for linear programming have become quite sophisticated, while extensions to more general classes of problems, such as convex quadratic programming, semi-definite programming, and nonconvex and nonlinear problems, have reached varying levels of maturity. We review some of the key developments in the area, including comments on both the complexity theory and practical algorithms for linear programming, semi-definite programming, monotone linear complementarity, and convex programming over sets that can be characterized by self-concordant barrier functions.

  10. Methods in Bioengineering

    Nahmias, Yaakov


    Offering a practical look into the field, this volume presents the science behind microscale device design and the engineering of its fabrication. Supported with dozens of full-color illustrations, this book offers you clear, step-by-step methods for the cell capture from whole blood, high-throughput study of transcriptional dynamics in living cells, temporal control of cell-cell interaction, nanoscale measurements of cellular forces, immobilizing living c. elegans, optical and electrical on-chip cell sorting and human-on-chip modeling of drug metabolism.

  11. Mathematical methods for physicists

    Arfken, George B


    Mathematical Methods for Physicists, Third Edition provides an advanced undergraduate and beginning graduate study in physical science, focusing on the mathematics of theoretical physics. This edition includes sections on the non-Cartesian tensors, dispersion theory, first-order differential equations, numerical application of Chebyshev polynomials, the fast Fourier transform, and transfer functions. Many of the physical examples provided in this book, which are used to illustrate the applications of mathematics, are taken from the fields of electromagnetic theory and quantum mechanics. The He

  12. Object oriented methods

    Graham, Ian


    This book is a revision of Ian Graham's successful survey of the whole area of object technology. It covers object- oriented programming, object-oriented design, object- oriented analysis, object-oriented databases and treats several related technologies. New to this edition are more applications of object-oriented methods and more coverage of object-oriented database products available. Graham has also doubled the design and analysis material that examines over 60 different approaches - making this the most comprehensive book on the market. Also new is the foreword by Grady Booch.

  13. Hydraulic mining method

    Huffman, Lester H.; Knoke, Gerald S.


    A method of hydraulically mining an underground pitched mineral vein comprising drilling a vertical borehole through the earth's lithosphere into the vein and drilling a slant borehole along the footwall of the vein to intersect the vertical borehole. Material is removed from the mineral vein by directing a high pressure water jet thereagainst. The resulting slurry of mineral fragments and water flows along the slant borehole into the lower end of the vertical borehole from where it is pumped upwardly through the vertical borehole to the surface.

  14. Method of joining ceramics

    Henager, Jr., Charles H.; Brimhall, John L.


    According to the method of the present invention, joining a first bi-element carbide to a second bi-element carbide, has the steps of: (a) forming a bond agent containing a metal carbide and silicon; (b) placing the bond agent between the first and second bi-element carbides to form a pre-assembly; and (c) pressing and heating the pre-assembly in a non-oxidizing atmosphere to a temperature effective to induce a displacement reaction creating a metal silicon phase bonding the first and second bi-element carbides.


    Russell, E.R.; Adamson, A.S.; Schubert, J.; Boyd, G.E.


    A method is presented for separating plutonium values from fission product values in aqueous acidic solution. This is accomplished by flowing the solutlon containing such values through a bed of zirconium orthophosphate. Any fission products adsorbed can subsequently be eluted by washing the column with a solution of 2N HNO/sub 3/ and O.lN H/sub 3/PO/sub 4/. Plutonium values may subsequently be desorbed by contacting the column with a solution of 7N HNO/sub 3/ .

  16. Control system design method

    Wilson, David G [Tijeras, NM; Robinett, III, Rush D.


    A control system design method and concomitant control system comprising representing a physical apparatus to be controlled as a Hamiltonian system, determining elements of the Hamiltonian system representation which are power generators, power dissipators, and power storage devices, analyzing stability and performance of the Hamiltonian system based on the results of the determining step and determining necessary and sufficient conditions for stability of the Hamiltonian system, creating a stable control system based on the results of the analyzing step, and employing the resulting control system to control the physical apparatus.

  17. Interval methods: An introduction

    Achenie, L.E.K.; Kreinovich, V.; Madsen, Kaj


    This chapter contains selected papers presented at the Minisymposium on Interval Methods of the PARA'04 Workshop '' State-of-the-Art in Scientific Computing ''. The emphasis of the workshop was on high-performance computing (HPC). The ongoing development of ever more advanced computers provides....... An important characteristic of the computer performance in scientific computing is the accuracy of the Computation results. Often, we can estimate this accuracy by using traditional statistical techniques. However, in many practical situations, we do not know the probability distributions of different...... '' techniques, and the applications of these techniques to various problems of scientific computing....

  18. Introduction to Numerical Methods

    Schoonover, Joseph A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)


    These are slides for a lecture for the Parallel Computing Summer Research Internship at the National Security Education Center. This gives an introduction to numerical methods. Repetitive algorithms are used to obtain approximate solutions to mathematical problems, using sorting, searching, root finding, optimization, interpolation, extrapolation, least squares regresion, Eigenvalue problems, ordinary differential equations, and partial differential equations. Many equations are shown. Discretizations allow us to approximate solutions to mathematical models of physical systems using a repetitive algorithm and introduce errors that can lead to numerical instabilities if we are not careful.

  19. Formal Methods in Industry

    Alexei Serna A.


    Full Text Available The application of formal methods in industry has progressed extensively over the past decade and the results are promising. But despite these achievements and it have been documented in numerous studies, it is still very common the skepticism about its usefulness and applicability. The goal of this paper is to show that its evolution over the past decade exceeds all previous processes and each time they do a better job to satisfy industrial needs. This is achieved by the description of some experiments and the result of various applications in industry and through an analyzing of the needs of companies that must be satisfy the research community in this field.

  20. Methods of thermodynamics

    Reiss, Howard


    Since there is no shortage of excellent general books on elementary thermodynamics, this book takes a different approach, focusing attention on the problem areas of understanding of concept and especially on the overwhelming but usually hidden role of ""constraints"" in thermodynamics, as well as on the lucid exposition of the significance, construction, and use (in the case of arbitrary systems) of the thermodynamic potential. It will be especially useful as an auxiliary text to be used along with any standard treatment.Unlike some texts, Methods of Thermodynamics does not use statistical m

  1. Calcium measurement methods

    CarloAlberto Redi


    Full Text Available Rightly stressed by prof. Wolfgang Walz in the Preface to the series Neuromethods series, the “careful application of methods is probably the most important step in the process of scientific inquiry”. Thus, I strongly suggest to all those interested in calcium signaling and especially to the new-comers in the hot topic of neuroscience (which has so much space even in science-society debate for its implications in legal issues and in the judge-decision process to take profit from this so well edited book. I am saying this since prof. Verkhratsky and prof. Petersen......

  2. Recombinant methods and materials

    Roizman, B.; Post, L.E.


    This patent describes a method for stably effecting the insertion or deletion of a selected DNA sequence at a specific site in a viral genome. The method consists of: (1) isolating from the genome a linear DNA fragment comprising both (a) the specific site determined for insertion or deletion of selected DNA sequence and (b) flanking DNA sequences normally preceding and following the site; (2) preparing first and second altered genome fragments from the fragment isolated in step (1). (a) the first altered fragment comprising the fragment comprising a thymidine kinase gene in a position intermediate the ends of the fragment, and (b) the second altered fragment comprising the fragment having the selected DNA sequence inserted therein or deleted therefrom; (3) contacting the genome with the first altered fragment under conditions permitting recombination at sites of DNA sequence homology, selecting for a recombinant genome comprising the thymidine kinase gene, and isolating the recombinant genome; and (4) contacting the recombinant genome isolated in step (3) with the second altered fragment under conditions permitting recombination at sites of DNA sequence homology, selecting for a recombinant genome lacking the thymidine kinase gene, and isolating the recombinant genome product.

  3. Research methods in information

    Pickard, Alison Jane


    The long-awaited 2nd edition of this best-selling research methods handbook is fully updated and includes brand new coverage of online research methods and techniques, mixed methodology and qualitative analysis. There is an entire chapter contributed by Professor Julie McLeod, Sue Childs and Elizabeth Lomas focusing on research data management, applying evidence from the recent JISC funded 'DATUM' project. The first to focus entirely on the needs of the information and communications community, it guides the would-be researcher through the variety of possibilities open to them under the heading "research" and provides students with the confidence to embark on their dissertations. The focus here is on the 'doing' and although the philosophy and theory of research is explored to provide context, this is essentially a practical exploration of the whole research process with each chapter fully supported by examples and exercises tried and tested over a whole teaching career. The book will take readers through eac...

  4. Nanoscale waveguiding methods

    Wang Chia-Jean


    Full Text Available AbstractWhile 32 nm lithography technology is on the horizon for integrated circuit (IC fabrication, matching the pace for miniaturization with optics has been hampered by the diffraction limit. However, development of nanoscale components and guiding methods is burgeoning through advances in fabrication techniques and materials processing. As waveguiding presents the fundamental issue and cornerstone for ultra-high density photonic ICs, we examine the current state of methods in the field. Namely, plasmonic, metal slot and negative dielectric based waveguides as well as a few sub-micrometer techniques such as nanoribbons, high-index contrast and photonic crystals waveguides are investigated in terms of construction, transmission, and limitations. Furthermore, we discuss in detail quantum dot (QD arrays as a gain-enabled and flexible means to transmit energy through straight paths and sharp bends. Modeling, fabrication and test results are provided and show that the QD waveguide may be effective as an alternate means to transfer light on sub-diffraction dimensions.

  5. Methods of Endotoxin Detection.

    Su, Wenqiong; Ding, Xianting


    Endotoxin, present in the outer membrane of all gram-negative bacteria, can pose serious risks to human health, from irreversible shock to death. Therefore, it is essential to develop sensitive, accurate, and rapid methods for its detection. The rabbit pyrogen test is the first standard technique for endotoxin detection and, nowadays, has been replaced by the Limulus Amoebocyte Lysate test, which is the most popular detection technique for endotoxin. With in-depth understanding of endotoxin, biosensors based on endotoxin-sensing components are promising alternatives to pursue in developing low-cost, easy-operation, and fast-response endotoxin detection techniques. This article summarizes the recent advances of endotoxin detection methods with a particular emphasis on optical and electrochemical biosensors based on various sensing elements ranging from nature biomolecules to artificial materials. As the research and technological revolution continues, the highly integrated and miniaturized commercial devices for sensitively and reliably detecting endotoxin will provide a wide range of applications in people's daily life.

  6. Epitope prediction methods

    Karosiene, Edita

    Major histocompatibility complex (MHC) molecules play a crucial role in adaptive immunity by sampling peptides from self and non-self proteins to be recognised by the immune system. MHC molecules present peptides on cell surfaces for recognition by CD8+ and CD4+ T lymphocytes that can initiate...... immune responses. Therefore, it is of great importance to be able to identify peptides that bind to MHC molecules, in order to understand the nature of immune responses and discover T cell epitopes useful for designing new vaccines and immunotherapies. MHC molecules in humans, referred to as human...... on machine learning techniques. Several MHC class I binding prediction algorithms have been developed and due to their high accuracy they are used by many immunologists to facilitate the conventional experimental process of epitope discovery. However, the accuracy of these methods depends on data defining...


    Fisher, R.W.


    A method is described for recovering thorium from impurities found in a slag containing thorium and said impurities, comprising leaching a composition containing thorium with water, removing the water solution, treating the residue with hydrochloric acid, separating the solution from the insoluble residue, adjusting its acidity to 1 to 3 normal, adding oxalic acid, and thereafter separating the precipitated thorium oxalate digesting the residue from the hydrochloric acid treatment with a strong solution of sodium hydroxide at an elevated temperature, removing said solution and treating the insoluble residue with hydrochloric acid, separating the solution from the insoluble residue, adjusting the acidity of this solution to 1 to 3 normal, adding nitric acid to oxidize the iron present, adding oxalic acid and thereafter separating the thorium oxalate thus precipitated.

  8. Method for radioactivity monitoring

    Umbarger, C. John; Cowder, Leo R.


    The disclosure relates to a method for analyzing uranium and/or thorium contents of liquid effluents preferably utilizing a sample containing counting chamber. Basically, 185.7-keV gamma rays following .sup.235 U alpha decay to .sup.231 Th which indicate .sup.235 U content and a 63-keV gamma ray doublet found in the nucleus of .sup.234 Pa, a granddaughter of .sup.238 U, are monitored and the ratio thereof taken to derive uranium content and isotopic enrichment .sup.235 U/.sup.235 U + .sup.238 U) in the liquid effluent. Thorium content is determined by monitoring the intensity of 238-keV gamma rays from the nucleus of .sup.212 Bi in the decay chain of .sup.232 Th.

  9. Radioactive air sampling methods

    Maiello, Mark L


    Although the field of radioactive air sampling has matured and evolved over decades, it has lacked a single resource that assimilates technical and background information on its many facets. Edited by experts and with contributions from top practitioners and researchers, Radioactive Air Sampling Methods provides authoritative guidance on measuring airborne radioactivity from industrial, research, and nuclear power operations, as well as naturally occuring radioactivity in the environment. Designed for industrial hygienists, air quality experts, and heath physicists, the book delves into the applied research advancing and transforming practice with improvements to measurement equipment, human dose modeling of inhaled radioactivity, and radiation safety regulations. To present a wide picture of the field, it covers the international and national standards that guide the quality of air sampling measurements and equipment. It discusses emergency response issues, including radioactive fallout and the assets used ...

  10. Geophysical Methods: an Overview

    Becker, A.; Goldstein, N. E.; Lee, K. H.; Majer, E. L.; Morrison, H. F.; Myer, L.


    Geophysics is expected to have a major role in lunar resource assessment when manned systems return to the Moon. Geophysical measurements made from a lunar rover will contribute to a number of key studies: estimating regolith thickness, detection of possible large-diameter lava tubes within maria basalts, detection of possible subsurface ice in polar regions, detection of conductive minerals that formed directly from a melt (orthomagmatic sulfides of Cu, Ni, Co), and mapping lunar geology beneath the regolith. The techniques that can be used are dictated both by objectives and by our abilities to adapt current technology to lunar conditions. Instrument size, weight, power requirements, and freedom from orientation errors are factors we have considered. Among the geophysical methods we believe to be appropriate for a lunar resource assessment are magnetics, including gradiometry, time-domain magnetic induction, ground-penetrating radar, seismic reflection, and gravimetry.

  11. Dominant modal decomposition method

    Dombovari, Zoltan


    The paper deals with the automatic decomposition of experimental frequency response functions (FRF's) of mechanical structures. The decomposition of FRF's is based on the Green function representation of free vibratory systems. After the determination of the impulse dynamic subspace, the system matrix is formulated and the poles are calculated directly. By means of the corresponding eigenvectors, the contribution of each element of the impulse dynamic subspace is determined and the sufficient decomposition of the corresponding FRF is carried out. With the presented dominant modal decomposition (DMD) method, the mode shapes, the modal participation vectors and the modal scaling factors are identified using the decomposed FRF's. Analytical example is presented along with experimental case studies taken from machine tool industry.

  12. A Pluralistic, Longitudinal Method

    Evers, Winie; Marroun, Sana; Young, Louise


    There is recognition in business markets of the need for connected relationships to enable the survival and growth of firms. Finding new ways to collaborate enables firms to better seek opportunities and challenges and enhance network capability. However the traditional methods used to research...... the development of network collaboration can be limited in the insights they provide as they often focus on single interviews in a single time perspective and/or are analyzed for content in a single way. The study presented here highlights the insights that can emerge from more pluralistic data collection...... on relationship and network assessments was measured by analysis of both the workshops’ discourse and by comparison of reflective interviews with participants before and after each workshop. Collective and comparative lexicographic (i.e. semantic) analysis was used to ascertain participants’ perceptions...

  13. Cyclostationarity theory and methods

    Leśkow, Jacek; Napolitano, Antonio; Sanchez-Ramirez, Andrea


    In the last decade the research in signal analysis was dominated by models that encompass nonstationarity as an important feature. This book presents the results of a workshop held in Grodek—Poland in February 2013 which was dedicated to the investigation of cyclostationary signals. Its main objective is to highlight the strong interactions between theory and applications of cyclostationary signals with the use of modern statistical tools. An important application of cyclostationary signals is the analysis of mechanical signals generated by a vibrating mechanism. Cyclostationary models are very important to perform basic operations on signals in both time and frequency domains. One of the fundamental problems in diagnosis of rotating machine is the identification of significant modulating frequencies that contribute to the cyclostationary nature of the signals. The book shows that there are modern tools available for analyzing cyclostationary signals without the assumption of gaussianity. Those methods are...

  14. Electrochemical catalyst recovery method

    Silva, Laura J.; Bray, Lane A.


    A method of recovering catalyst material from latent catalyst material solids includes: a) combining latent catalyst material solids with a liquid acid anolyte solution and a redox material which is soluble in the acid anolyte solution to form a mixture; b) electrochemically oxidizing the redox material within the mixture into a dissolved oxidant, the oxidant having a potential for oxidation which is effectively higher than that of the latent catalyst material; c) reacting the oxidant with the latent catalyst material to oxidize the latent catalyst material into at least one oxidized catalyst species which is soluble within the mixture and to reduce the oxidant back into dissolved redox material; and d) recovering catalyst material from the oxidized catalyst species of the mixture. The invention is expected to be particularly useful in recovering spent catalyst material from petroleum hydroprocessing reaction waste products having adhered sulfides, carbon, hydrocarbons, and undesired metals, and as well as in other industrial applications.

  15. Microencapsulation system and method

    Morrison, Dennis R. (Inventor)


    A microencapsulation apparatus is provided which is configured to form co-axial multi-lamellar microcapsules from materials discharged from first and second microsphere dispensers of the apparatus. A method of fabricating and processing microcapsules is also provided which includes forming distinct droplets comprising one or more materials and introducing the droplets directly into a solution bath to form a membrane around the droplets such that a plurality of microcapsules are formed. A microencapsulation system is provided which includes a microcapsule production unit, a fluidized passage for washing and harvesting microcapsules dispensed from the microcapsule production unit and a flow sensor for sizing and counting the microcapsules. In some embodiments, the microencapsulation system may further include a controller configured to simultaneously operate the microcapsule production unit, fluidized passage and flow sensor to process the microcapsules in a continuous manner.

  16. Unconventional methods for clustering

    Kotyrba, Martin


    Cluster analysis or clustering is a task of grouping a set of objects in such a way that objects in the same group (called a cluster) are more similar (in some sense or another) to each other than to those in other groups (clusters). It is the main task of exploratory data mining and a common technique for statistical data analysis used in many fields, including machine learning, pattern recognition, image analysis, information retrieval, and bioinformatics. The topic of this paper is one of the modern methods of clustering namely SOM (Self Organising Map). The paper describes the theory needed to understand the principle of clustering and descriptions of algorithm used with clustering in our experiments.

  17. Floating Silicon Method

    Kellerman, Peter


    The Floating Silicon Method (FSM) project at Applied Materials (formerly Varian Semiconductor Equipment Associates), has been funded, in part, by the DOE under a “Photovoltaic Supply Chain and Cross Cutting Technologies” grant (number DE-EE0000595) for the past four years. The original intent of the project was to develop the FSM process from concept to a commercially viable tool. This new manufacturing equipment would support the photovoltaic industry in following ways: eliminate kerf losses and the consumable costs associated with wafer sawing, allow optimal photovoltaic efficiency by producing high-quality silicon sheets, reduce the cost of assembling photovoltaic modules by creating large-area silicon cells which are free of micro-cracks, and would be a drop-in replacement in existing high efficiency cell production process thereby allowing rapid fan-out into the industry.

  18. New methods in cytogenetics.

    Buckle, V J; Kearney, L


    Developments in the technique of fluorescence in situ hybridization (FISH) now permit hybridization of sequences ranging from 1 kb to whole genomes. The technique can be used in applications from coarse mapping of whole chromosomes to high-resolution analysis of extended strands of DNA. The complexity, and hence the coverage, of 'paints' prepared by amplification is being improved to the extent that such methods are used in cloning strategies for the generation of region-specific probes. Interphase analysis and comparative genomic hybridization are becoming important tools in cancer cytogenetics, and the potential for routine analysis of fetal cells obtained from maternal blood may provide a fresh approach to prenatal cytogenetic screening. Functional studies of gene activity and nuclear organization are now also possible.

  19. Extending the MINLO method

    Frederix, Rikkert


    We consider improving POWHEG+MINLO simulations, so as to also render them NLO accurate in the description of observables receiving contributions from events with lower parton multiplicity than present in their underlying NLO calculation. On a conceptual level we follow the strategy of the so-called MINLO' programs. Whereas the existing MINLO' framework requires explicit analytic input from higher order resummation, here we derive an effective numerical approximation to these ingredients, by imposing unitarity. This offers a way of extending the MINLO' method to more complex processes, complementary to the known route which uses explicit computations of high-accuracy resummation inputs. Specifically, we have focused on Higgs-plus-two-jet production (HJJ) and related processes. We also consider how one can cover three units of multiplicity at NLO accuracy, i.e. we consider how the HJJ-MINLO simulation may yield NLO accuracy for inclusive H, HJ, and HJJ quantities. We perform a feasibility study assessing the po...

  20. Data mining methods

    Chattamvelli, Rajan


    DATA MINING METHODS, Second Edition discusses both theoretical foundation and practical applications of datamining in a web field including banking, e-commerce, medicine, engineering and management. This book starts byintroducing data and information, basic data type, data category and applications of data mining. The second chapterbriefly reviews data visualization technology and importance in data mining. Fundamentals of probability and statisticsare discussed in chapter 3, and novel algorithm for sample covariants are derived. The next two chapters give an indepthand useful discussion of data warehousing and OLAP. Decision trees are clearly explained and a new tabularmethod for decision tree building is discussed. The chapter on association rules discusses popular algorithms andcompares various algorithms in summary table form. An interesting application of genetic algorithm is introduced inthe next chapter. Foundations of neural networks are built from scratch and the back propagation algorithm is derived...

  1. Methods for RNA Analysis

    Olivarius, Signe

    While increasing evidence appoints diverse types of RNA as key players in the regulatory networks underlying cellular differentiation and metabolism, the potential functions of thousands of conserved RNA structures encoded in mammalian genomes remain to be determined. Since the functions of most...... RNAs rely on interactions with proteins, the establishment of protein-binding profiles is essential for the characterization of RNAs. Aiming to facilitate RNA analysis, this thesis introduces proteomics- as well as transcriptomics-based methods for the functional characterization of RNA. First, RNA......-protein pulldown combined with mass spectrometry analysis is applied for in vivo as well as in vitro identification of RNA-binding proteins, the latter succeeding in verifying known RNA-protein interactions. Secondly, acknowledging the significance of flexible promoter usage for the diversification...

  2. Remanufacturability and Assessment Method

    ZHU Sheng; CUI Pei-zhi; YAO Ju-kun


    Remanufacturing represents the combination of "three Rs" (reduce, reuse, recycle) into a single activity, which restores a wide variety of worn-out, discarded durable products to like-new condition, prolonging theit useful life,protecting the environment. The application of surface engineering has promoted the development of remanufacturing.Remanufacturing is an environmentally and economically sound way to achieve many of the goals of sustainable development. Through developing study of product design for remanufacturing, it can promote the surface technologies application in the remanufacturing, and markedly enhance the efficiency of remanufacturing. This paper gives some relative concepts about product design for remanufacturing, such as remanufacturability, and brings forward the remanufacturability research contents and assessment method of used product.

  3. Mathematical methods in engineering

    Machado, José


    This book presents a careful selection of the contributions presented at the Mathematical Methods in Engineering (MME10) International Symposium, held at the Polytechnic Institute of Coimbra- Engineering Institute of Coimbra (IPC/ISEC), Portugal, October 21-24, 2010. The volume discusses recent developments about theoretical and applied mathematics toward the solution of engineering problems, thus covering a wide range of topics, such as:  Automatic Control, Autonomous Systems, Computer Science, Dynamical Systems and Control,  Electronics, Finance and Economics, Fluid Mechanics and Heat Transfer, Fractional Mathematics, Fractional Transforms and Their Applications,  Fuzzy Sets and Systems, Image and Signal Analysis, Image Processing, Mechanics, Mechatronics, Motor Control and Human Movement Analysis, Nonlinear Dynamics, Partial Differential Equations, Robotics, Acoustics, Vibration and Control, and Wavelets.

  4. Remanufacturability and Assessment Method

    ZHUSheng; CUIPei-zhi; YAOJu-kun


    Remanufacturing represents the combination of "three Rs" (reduce, reuse, recycle) into a single activity, which restores a wide variety of worn-out, discarded durable products to like-new condition, prolonging their useful life, protecting the environment. The application of surface engineering has promoted the development of remanufacturing. Remanufacturing is an environmentally and economically sound way to achieve many of the goals of sustainable development. Through developing study of product design for remanufacturing, it can promote the surface technologies application in the remanufacturing, and markedly enhance the efficiency of remanufacturing. This paper gives some relative concepts about product design for remanufacturing, such as remanufacturability, and brings forward the remanufacturability research contents and assessment method of used product.

  5. Gas centrifuge purge method

    Theurich, Gordon R.


    1. In a method of separating isotopes in a high speed gas centrifuge wherein a vertically oriented cylindrical rotor bowl is adapted to rotate about its axis within an evacuated chamber, and wherein an annular molecular pump having an intake end and a discharge end encircles the uppermost portion of said rotor bowl, said molecular pump being attached along its periphery in a leak-tight manner to said evacuated chamber, and wherein end cap closure means are affixed to the upper end of said rotor bowl, and a process gas withdrawal and insertion system enters said bowl through said end cap closure means, said evacuated chamber, molecular pump and end cap defining an upper zone at the discharge end of said molecular pump, said evacuated chamber, molecular pump and rotor bowl defining a lower annular zone at the intake end of said molecular pump, a method for removing gases from said upper and lower zones during centrifuge operation with a minimum loss of process gas from said rotor bowl, comprising, in combination: continuously measuring the pressure in said upper zone, pumping gas from said lower zone from the time the pressure in said upper zone equals a first preselected value until the pressure in said upper zone is equal to a second preselected value, said first preselected value being greater than said second preselected value, and continuously pumping gas from said upper zone from the time the pressure in said upper zone equals a third preselected value until the pressure in said upper zone is equal to a fourth preselected value, said third preselected value being greater than said first, second and fourth preselected values.

  6. Characterization Methods of Encapsulates

    Zhang, Zhibing; Law, Daniel; Lian, Guoping

    , reliable methods which can be used to characterize these properties of encapsulates are vital. In this chapter, the state-of-art of these methods, their principles and applications, and release mechanisms are described as follows.

  7. Methods and Technologies Branch (MTB)

    The Methods and Technologies Branch focuses on methods to address epidemiologic data collection, study design and analysis, and to modify technological approaches to better understand cancer susceptibility.

  8. Comparative law as method and the method of comparative law

    Hage, J.C.; Adams, M.; Heirbaut, D.


    This article addresses both the justificatory role of comparative law within legal research (comparative law as method) and the method of comparative law itself. In this connection two questions will be answered: 1. Is comparative law a method, or a set of methods, for legal research? 2. Does compar

  9. Conference on Logical Methods

    Remmel, Jeffrey; Shore, Richard; Sweedler, Moss; Progress in Computer Science and Applied Logic


    The twenty-six papers in this volume reflect the wide and still expanding range of Anil Nerode's work. A conference on Logical Methods was held in honor of Nerode's sixtieth birthday (4 June 1992) at the Mathematical Sciences Institute, Cornell University, 1-3 June 1992. Some of the conference papers are here, but others are from students, co-workers and other colleagues. The intention of the conference was to look forward, and to see the directions currently being pursued, in the development of work by, or with, Nerode. Here is a brief summary of the contents of this book. We give a retrospective view of Nerode's work. A number of specific areas are readily discerned: recursive equivalence types, recursive algebra and model theory, the theory of Turing degrees and r.e. sets, polynomial-time computability and computer science. Nerode began with automata theory and has also taken a keen interest in the history of mathematics. All these areas are represented. The one area missing is Nerode's applied mathematica...

  10. Production Methods for Hyaluronan

    Carmen G. Boeriu


    Full Text Available Hyaluronan is a polysaccharide with multiple functions in the human body being involved in creating flexible and protective layers in tissues and in many signalling pathways during embryonic development, wound healing, inflammation, and cancer. Hyaluronan is an important component of active pharmaceutical ingredients for treatment of, for example, arthritis and osteoarthritis, and its commercial value far exceeds that of other microbial extracellular polysaccharides. Traditionally hyaluronan is extracted from animal waste which is a well-established process now. However, biotechnological synthesis of biopolymers provides a wealth of new possibilities. Therefore, genetic/metabolic engineering has been applied in the area of tailor-made hyaluronan synthesis. Another approach is the controlled artificial (in vitro synthesis of hyaluronan by enzymes. Advantage of using microbial and enzymatic synthesis for hyaluronan production is the simpler downstream processing and a reduced risk of viral contamination. In this paper an overview of the different methods used to produce hyaluronan is presented. Emphasis is on the advancements made in the field of the synthesis of bioengineered hyaluronan.

  11. Statistical methods for forecasting

    Abraham, Bovas


    The Wiley-Interscience Paperback Series consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists."This book, it must be said, lives up to the words on its advertising cover: ''Bridging the gap between introductory, descriptive approaches and highly advanced theoretical treatises, it provides a practical, intermediate level discussion of a variety of forecasting tools, and explains how they relate to one another, both in theory and practice.'' It does just that!"-Journal of the Royal Statistical Society"A well-written work that deals with statistical methods and models that can be used to produce short-term forecasts, this book has wide-ranging applications. It could be used in the context of a study of regression, forecasting, and time series ...

  12. Acoustic data transmission method

    Duckworth, A.


    This patent describes a method for transmitting time line data through a drillstring having drill pipe sections connected end-to-end by joints from a first location below the surface of the earth to a second location at or near the surface of the earth, the length and cross-sectional area of the drill pipe sections being different from the length and cross-sectional area of the joints. It comprises generating acoustic data signals having a single frequency content in at least one passband of the drillstring; transmitting the data signals through the drillstring from either the first location to the second location or from the second location to the first location during a time period prior to the onset of reflective interference caused by the data signals reflecting from along the length of the drillstring, the time period being equal to or less than the time for the data signals to travel three lengths of the drillstring; stopping the transmission of data signals at the onset of the reflective interference and allowing the acoustic signals to substantially attenuate; and detecting the data signals at the respective first or second location.

  13. NCSX Plasma Heating Methods

    H.W. Kugel; D. Spong; R. Majeski; M. Zarnstorff


    The NCSX (National Compact Stellarator Experiment) has been designed to accommodate a variety of heating systems, including ohmic heating, neutral-beam injection, and radio-frequency. Neutral beams will provide one of the primary heating methods for NCSX. In addition to plasma heating, beams are also expected to provide a means for external control over the level of toroidal plasma rotation velocity and its profile. The plan is to provide 3 MW of 50 keV balanced neutral-beam tangential injection with pulse lengths of 500 msec for initial experiments, and to be upgradeable to pulse lengths of 1.5 sec. Subsequent upgrades will add 3 MW of neutral-beam injection. This Chapter discusses the NCSX neutral-beam injection requirements and design issues, and shows how these are provided by the candidate PBX-M (Princeton Beta Experiment-Modification) neutral-beam injection system. In addition, estimations are given for beam-heating efficiencies, scaling of heating efficiency with machine size an d magnetic field level, parameter studies of the optimum beam-injection tangency radius and toroidal injection location, and loss patterns of beam ions on the vacuum chamber wall to assist placement of wall armor and for minimizing the generation of impurities by the energetic beam ions. Finally, subsequent upgrades could add an additional 6 MW of radio-frequency heating by mode-conversion ion-Bernstein wave (MCIBW) heating, and if desired as possible future upgrades, the design also will accommodate high-harmonic fast-wave and electron-cyclotron heating. The initial MCIBW heating technique and the design of the radio-frequency system lend themselves to current drive, so that if current drive became desirable for any reason only minor modifications to the heating system described here would be needed. The radio-frequency system will also be capable of localized ion heating (bulk or tail), and possibly ion-Bernstein-wave-generated sheared flows.

  14. NCSX Plasma Heating Methods

    Kugel, H. W.; Spong, D.; Majeski, R.; Zarnstorff, M.


    The National Compact Stellarator Experiment (NCSX) has been designed to accommodate a variety of heating systems, including ohmic heating, neutral beam injection, and radio-frequency (rf). Neutral beams will provide one of the primary heating methods for NCSX. In addition to plasma heating, neutral beams are also expected to provide a means for external control over the level of toroidal plasma rotation velocity and its profile. The experimental plan requires 3 MW of 50-keV balanced neutral beam tangential injection with pulse lengths of 500 ms for initial experiments, to be upgradeable to pulse lengths of 1.5 s. Subsequent upgrades will add 3MW of neutral beam injection (NBI). This paper discusses the NCSX NBI requirements and design issues and shows how these are provided by the candidate PBX-M NBI system. In addition, estimations are given for beam heating efficiencies, scaling of heating efficiency with machine size and magnetic field level, parameter studies of the optimum beam injection tangency radius and toroidal injection location, and loss patterns of beam ions on the vacuum chamber wall to assist placement of wall armor and for minimizing the generation of impurities by the energetic beam ions. Finally, subsequent upgrades could add an additional 6 MW of rf heating by mode conversion ion Bernstein wave (MCIBW) heating, and if desired as possible future upgrades, the design also will accommodate high-harmonic fast-wave and electron cyclotron heating. The initial MCIBW heating technique and the design of the rf system lend themselves to current drive, so if current drive became desirable for any reason, only minor modifications to the heating system described here would be needed. The rf system will also be capable of localized ion heating (bulk or tail), and possiblyIBW-generated sheared flows.

  15. A method cache for Patmos

    Degasperi, Philipp; Hepp, Stefan; Puffitsch, Wolfgang;


    For real-time systems we need time-predictable processors. This paper presents a method cache as a time-predictable solution for instruction caching. The method cache caches whole methods (or functions) and simplifies worst-case execution time analysis. We have integrated the method cache...

  16. 40 years of formal methods

    Bjørner, Dines; Havelund, Klaus


    In this "40 years of formal methods" essay we shall first delineate, Sect. 1, what we mean by method, formal method, computer science, computing science, software engineering, and model-oriented and algebraic methods. Based on this, we shall characterize a spectrum from specification......-oriented methods to analysis-oriented methods. Then, Sect. 2, we shall provide a "survey": which are the 'prerequisite works' that have enabled formal methods, Sect. 2.1, and which are, to us, the, by now, classical 'formal methods', Sect. 2.2. We then ask ourselves the question: have formal methods for software...... development, in the sense of this paper been successful? Our answer is, regretfully, no! We motivate this answer, in Sect. 3.2, by discussing eight obstacles or hindrances to the proper integration of formal methods in university research and education as well as in industry practice. This "looking back...

  17. Explorative methods in linear models

    Høskuldsson, Agnar


    The author has developed the H-method of mathematical modeling that builds up the model by parts, where each part is optimized with respect to prediction. Besides providing with better predictions than traditional methods, these methods provide with graphic procedures for analyzing different...... features in data. These graphic methods extend the well-known methods and results of Principal Component Analysis to any linear model. Here the graphic procedures are applied to linear regression and Ridge Regression....

  18. Method Points: towards a metric for method complexity

    Graham McLeod


    Full Text Available A metric for method complexity is proposed as an aid to choosing between competing methods, as well as in validating the effects of method integration or the products of method engineering work. It is based upon a generic method representation model previously developed by the author and adaptation of concepts used in the popular Function Point metric for system size. The proposed technique is illustrated by comparing two popular I.E. deliverables with counterparts in the object oriented Unified Modeling Language (UML. The paper recommends ways to improve the practical adoption of new methods.


    Sessler, A.M.


    But a glance at the Livingston chart, Fig. 1, of accelerator particle energy as a function of time shows that the energy has steadily, exponentially, increased. Equally significant is the fact that this increase is the envelope of diverse technologies. If one is to stay on, or even near, the Livingston curve in future years then new acceleration techniques need to be developed. What are the new acceleration methods? In these two lectures I would like to sketch some of these new ideas. I am well aware that they will probably not result in high energy accelerators within this or the next decade, but conversely, it is likely that these ideas will form the basis for the accelerators of the next century. Anyway, the ideas are stimulating and suffice to show that accelerator physicists are not just 'engineers', but genuine scientists deserving to be welcomed into the company of high energy physicists. I believe that outsiders will find this field surprisingly fertile and, certainly fun. To put it more personally, I very much enjoy working in this field and lecturing on it. There are a number of review articles which should be consulted for references to the original literature. In addition there are three books on the subject. Given this material, I feel free to not completely reference the material in the remainder of this article; consultation of the review articles and books will be adequate as an introduction to the literature for references abound (hundreds are given). At last, by way of introduction, I should like to quote from the end of Ref. 2 for I think the remarks made there are most germane. Remember that the talk was addressed to accelerator physicists: 'Finally, it is often said, I think by physicists who are not well-informed, that accelerator builders have used up their capital and now are bereft of ideas, and as a result, high energy physics will eventually--rather soon, in fact--come to a halt. After all, one can't build too many

  20. Renal and urinary levels of endothelial protein C receptor correlate with acute renal allograft rejection.

    Lionel Lattenist

    Full Text Available The Endothelial Protein C Receptor (EPCR is expressed on leukocytes, on endothelium of large blood vessels and to a lesser extent on capillaries. Membrane bound EPCR plays an important role in the activation of protein C which has anticoagulant, anti-inflammatory and cytoprotective effects. After cleavage by a protease EPCR is also found as a soluble protein. Acute rejection of kidney allografts can be divided in T-cell-mediated rejection (TCMR and antibody-mediated (ABMR rejection. The latter is characterized by strong activation of coagulation. Currently no reliable non-invasive biomarkers are available to monitor rejection. Renal biopsies were available from 81 renal transplant patients (33 without rejection, 26 TCMR and 22 ABMR, we had access to mRNA material, matched plasma and urine samples for a portion of this cohort. Renal EPCR expression was assessed by RT-PCR and immunostaining. Plasma and urine sEPCR levels were measured by ELISA. ABMR patients showed higher levels of EPCR mRNA than TCMR patients. EPCR expression on glomeruli was significantly elevated in ABMR patients than in TCMR or control patients. In the peritubular capillaries EPCR expression was higher in ABMR patients than in control patients. EPCR expression was higher in tubules and arteries of rejection patients than in control patients. Plasma sEPCR levels did not differ. Urine sEPCR levels were more elevated in the ABMR group than in patients with TCMR or without rejection. ROC analysis demonstrated that urinary sEPCR is appropriate to discriminate between ABMR patients and TCMR or control patients. We conclude that urinary sEPCR could be a novel non-invasive biomarker of antibody mediated rejection in renal transplantation.

  1. Dianhydrides, polyimides, methods of making each, and methods of use

    Ma, Xiaohua


    Embodiments of the present disclosure provide for an aromatic dianhydride, a method of making an aromatic dianhydride, an aromatic dianhydride-based polyimide, a method of making an aromatic dianhydride-based polyimide, and the like.

  2. Alternative methods in toxicology: pre-validated and validated methods


    The development of alternative methods to animal experimentation has progressed rapidly over the last 20 years. Today, in vitro and in silico methods have an important role in the hazard identification and assessment of toxicology profile of compounds. Advanced alternative methods and their combinations are also used for safety assessment of final products. Several alternative methods, which were scientifically validated and accepted by competent regulatory bodies, can be used for regulatory ...

  3. Multiple Methods: Research Methods in Education Projects at NSF

    Suter, Larry E.


    Projects on science and mathematics education research supported by the National Science Foundation (US government) rarely employ a single method of study. Studies of educational practices that use experimental design are very rare. The most common research method is the case study method and the second most common is some form of experimental…

  4. Catalysts, methods of making catalysts, and methods of use

    Renard, Laetitia


    Embodiments of the present disclosure provide for catalysts, methods of making catalysts, methods of using catalysts, and the like. In an embodiment, the method of making the catalysts can be performed in a single step with a metal nanoparticle precursor and a metal oxide precursor, where a separate stabilizing agent is not needed.

  5. Stated preference methods using R

    Aizaki, Hideo; Sato, Kazuo


    Stated Preference Methods Using R explains how to use stated preference (SP) methods, which are a family of survey methods, to measure people's preferences based on decision making in hypothetical choice situations. Along with giving introductory explanations of the methods, the book collates information on existing R functions and packages as well as those prepared by the authors. It focuses on core SP methods, including contingent valuation (CV), discrete choice experiments (DCEs), and best-worst scaling (BWS). Several example data sets illustrate empirical applications of each method with R

  6. Blindman-Walking Optimization Method

    Chunming Li


    Full Text Available Optimization methods are all implemented with the hypothesis of unknowing the mathematic express of objective objection. Using the human analogy innovative method, the one-dimension blind-walking optimal method is proposed in this paper. The theory and the algorithm of this method includes halving, doubling, reversing probing step and verifying the applicability condition. Double-step is available to make current point moving to the extremum point. Half-step is available to accelerate convergence. In order to improve the optimization, the applicability condition decides whether update current point or not. The operation process, algorithmic flow chart and characteristic analysis of the method were given. Two optimization problems with unimodal or multimodal objective function were solved by the proposed method respectively. The simulation result shows that the proposed method is better than the ordinary method. The proposed method has the merit of rapid convergence, little calculation capacity, wide applicable range, etc. Taking the method as innovative kernel, the random research method, feasible direction method and complex shape method were improved. Taking the innovative content of this paper as innovative kernel, a monograph was published. The other innovations of the monograph are listed, such as applied algorithm of Karush-Kuhn-Tucker (KKT qualifications on judging the restriction extremum point, the design step of computing software, the complementarity and derivation of Powell criterion, the method of keeping the complex shape not to deduce dimension and the analysis of gradual optimization characteristic, the reinforced wall of inner point punish function method, the analysis of problem with constrained monstrosity extremum point, the improvement of Newton method and the validation of optimization idea of blind walking repeatedly, the explanation of later-day optimization method, the conformity of seeking algorithm needing the

  7. Numerical Methods for Stochastic Computations A Spectral Method Approach

    Xiu, Dongbin


    The first graduate-level textbook to focus on fundamental aspects of numerical methods for stochastic computations, this book describes the class of numerical methods based on generalized polynomial chaos (gPC). These fast, efficient, and accurate methods are an extension of the classical spectral methods of high-dimensional random spaces. Designed to simulate complex systems subject to random inputs, these methods are widely used in many areas of computer science and engineering. The book introduces polynomial approximation theory and probability theory; describes the basic theory of gPC meth

  8. Operator theory and numerical methods

    Fujita, H; Suzuki, T


    In accordance with the developments in computation, theoretical studies on numerical schemes are now fruitful and highly needed. In 1991 an article on the finite element method applied to evolutionary problems was published. Following the method, basically this book studies various schemes from operator theoretical points of view. Many parts are devoted to the finite element method, but other schemes and problems (charge simulation method, domain decomposition method, nonlinear problems, and so forth) are also discussed, motivated by the observation that practically useful schemes have fine mathematical structures and the converses are also true. This book has the following chapters: 1. Boundary Value Problems and FEM. 2. Semigroup Theory and FEM. 3. Evolution Equations and FEM. 4. Other Methods in Time Discretization. 5. Other Methods in Space Discretization. 6. Nonlinear Problems. 7. Domain Decomposition Method.

  9. Analytic Methods in Investigative Geometry.

    Dobbs, David E.


    Suggests an alternative proof by analytic methods, which is more accessible than rigorous proof based on Euclid's Elements, in which students need only apply standard methods of trigonometry to the data without introducing new points or lines. (KHR)

  10. Mixed methods research for TESOL

    Brown, James; Farr, Fiona


    Defining and discussing the relevance of theoretical and practical issues involved in mixed methods research. Covering the basics of research methodology, this textbook shows you how to choose and combine quantitative and qualitative research methods to b

  11. Birth control - slow release methods

    ... page: // Birth control - slow release methods To use the sharing features on this page, please enable JavaScript. Certain birth control methods contain man-made forms of hormones. These ...

  12. International Conference eXtended Discretization MethodS

    Benvenuti, Elena


    This book gathers selected contributions on emerging research work presented at the International Conference eXtended Discretization MethodS (X-DMS), held in Ferrara in September 2015. It highlights the most relevant advances made at the international level in the context of expanding classical discretization methods, like finite elements, to the numerical analysis of a variety of physical problems. The improvements are intended to achieve higher computational efficiency and to account for special features of the solution directly in the approximation space and/or in the discretization procedure. The methods described include, among others, partition of unity methods (meshfree, XFEM, GFEM), virtual element methods, fictitious domain methods, and special techniques for static and evolving interfaces. The uniting feature of all contributions is the direct link between computational methodologies and their application to different engineering areas.


    Hong-yu Liu; Geng Sun


    Properties of symplectic Runge-Kutta (RK) methods and symplectic partitioned RungeKutta (PRK) methods with real eigenvalues are discussed in this paper. It is shown that an s stage such method can't reach order more than s + 1. Particularly, we prove that no symplectic RK method with real eigenvalues exists in stage s of order s + 1 when s is even. But an example constructed by using the W-transformation shows that PRK method of this type does not necessarily meet this order barrier. Another useful way other than W-transformation to construct symplectic PRK method with real eigenvalues is then presented. Finally, a class of efficient symplectic methods is recommended.

  14. Mining method selection by integrated AHP and PROMETHEE method.

    Bogdanovic, Dejan; Nikolic, Djordje; Ilic, Ivana


    Selecting the best mining method among many alternatives is a multicriteria decision making problem. The aim of this paper is to demonstrate the implementation of an integrated approach that employs AHP and PROMETHEE together for selecting the most suitable mining method for the "Coka Marin" underground mine in Serbia. The related problem includes five possible mining methods and eleven criteria to evaluate them. Criteria are accurately chosen in order to cover the most important parameters that impact on the mining method selection, such as geological and geotechnical properties, economic parameters and geographical factors. The AHP is used to analyze the structure of the mining method selection problem and to determine weights of the criteria, and PROMETHEE method is used to obtain the final ranking and to make a sensitivity analysis by changing the weights. The results have shown that the proposed integrated method can be successfully used in solving mining engineering problems.

  15. Alternative methods in toxicology: pre-validated and validated methods.

    Kandárová, Helena; Letašiová, Silvia


    The development of alternative methods to animal experimentation has progressed rapidly over the last 20 years. Today, in vitro and in silico methods have an important role in the hazard identification and assessment of toxicology profile of compounds. Advanced alternative methods and their combinations are also used for safety assessment of final products. Several alternative methods, which were scientifically validated and accepted by competent regulatory bodies, can be used for regulatory toxicology purposes, thus reducing or fully replacing living animals in toxicology experimentation. The acceptance of the alternative methods as valuable tools of modern toxicology has been recognized by regulators, including OECD, FDA and EPA.This paper provides a brief overview of the topic "alternative methods in toxicology" and focuses on pre-validated and validated alternative methods and their position in the modern toxicology.

  16. Physics-compatible numerical methods

    Barry, Koren; Abgrall, Remi; Pavel, Bochev; Jason, Frank; Blair, Perrot


    International audience; Physics-compatible numerical methods are methods that aim to preserve key mathematical and physical properties of continuum physics models in their finite-dimensional algebraic representations. They include methods which preserve properties such as energy, monotonicity, maximum principles, symmetries, and involutions of the continuum models. Examples are mimetic methods for spatial discretizations, variational and geometric integrators, conservative finite-volume and f...

  17. Methods for Equating Mental Tests.


    1983) compared conventional and IRT methods for equating the Test of English as a Foreign Language ( TOEFL ) after chaining. Three conventional and...three IRT equating methods were examined in this study; two sections of TOEFL were each (separately) equated. The IRT methods included the following: ( A separate base form was established for each of the six equating methods. Instead of equating the base-form TOEFL to itself, the last (eighth

  18. Probabilistic methods for rotordynamics analysis

    Wu, Y.-T.; Torng, T. Y.; Millwater, H. R.; Fossum, A. F.; Rheinfurth, M. H.


    This paper summarizes the development of the methods and a computer program to compute the probability of instability of dynamic systems that can be represented by a system of second-order ordinary linear differential equations. Two instability criteria based upon the eigenvalues or Routh-Hurwitz test functions are investigated. Computational methods based on a fast probability integration concept and an efficient adaptive importance sampling method are proposed to perform efficient probabilistic analysis. A numerical example is provided to demonstrate the methods.

  19. Activity based costing (ABC Method

    Prof. Ph.D. Saveta Tudorache


    Full Text Available In the present paper the need and advantages are presented of using the Activity BasedCosting method, need arising from the need of solving the information pertinence issue. This issue has occurreddue to the limitation of classic methods in this field, limitation also reflected by the disadvantages ofsuch classic methods in establishing complete costs.

  20. Reduced basis heterogeneous multiscale methods

    Abdulle, Assyr


    Numerical methods for partial differential equations with multiple scales that combine numerical homogenization methods with reduced order modeling techniques are discussed. These numerical methods can be applied to a variety of problems including multiscale nonlinear elliptic and parabolic problems or Stokes flow in heterogenenous media.

  1. Another Form for LAMBDA Method

    ZHOU Yangmei; LIU Jingnan


    The LAMBDA methodthat was proposed by Teunissen is introduced. Then, on the basis of both the back-sequential conditional LS technique and the upper-triangular Cholesky decomposition, another form for LAMBDA method is proposed.This new form for LAMBDA method has the same principle and calculation speed as the traditional LAMBDA method.

  2. Method for alignment of microwires

    Beardslee, Joseph A.; Lewis, Nathan S.; Sadtler, Bryce


    A method of aligning microwires includes modifying the microwires so they are more responsive to a magnetic field. The method also includes using a magnetic field so as to magnetically align the microwires. The method can further include capturing the microwires in a solid support structure that retains the longitudinal alignment of the microwires when the magnetic field is not applied to the microwires.

  3. Multistep method for controlling chaos

    Starobinets, Igor M.; Pikovsky, Arkady S.


    We present a multistep control method where the trajectory on a chaotic attractor is directed by small perturbations towards a chosen fixed point. The method gives a significant reduction of the chaotic transient preceding the controlled motion as compared with the Ott-Grebogi-Yorke method. Transition from local to global control, when chaotic transients disappear, is discussed.

  4. Formal Methods in Knowledge Engineering

    Harmelen, van F.A.H.; Fensel, D.


    This paper presents a general discussion of the role of formal methods in Knowledge Engineering. We give an historical account of the development of the field of Knowledge Engineering towards the use of formal methods. Subsequently, we discuss the pro's and cons of formal methods. We do this by summ

  5. Indirect methods in nuclear astrophysics

    Bertulani, C A; Mukhamedzhanov, A; Kadyrov, A S; Kruppa, A; Pang, D Y


    We discuss recent developments in indirect methods used in nuclear astrophysics to determine the capture cross sections and subsequent rates of various stellar burning processes, when it is difficult to perform the corresponding direct measurements. We discuss in brief, the basic concepts of Asymptotic Normalization Coefficients, the Trojan Horse Method, the Coulomb Dissociation Method, (d,p), and charge-exchange reactions.

  6. Extraction Methods, Variability Encountered in

    Bodelier, P.L.E.; Nelson, K.E.


    Synonyms Bias in DNA extractions methods; Variation in DNA extraction methods Definition The variability in extraction methods is defined as differences in quality and quantity of DNA observed using various extraction protocols, leading to differences in outcome of microbial community composition as

  7. Excitation Methods for Bridge Structures

    Farrar, C.R.; Duffy, T.A.; Cornwell, P.J.; Doebling, S.W.


    This paper summarizes the various methods that have been used to excited bridge structures during dynamic testing. The excitation methods fall into the general categories of ambient excitation methods and measured-input excitation methods. During ambient excitation the input to the bridge is not directly measured. In contrast, as the category label implies, measured-input excitations are usually applied at a single location where the force input to the structure can be monitored. Issues associated with using these various types of measurements are discussed along with a general description of the various excitation methods.

  8. 40 years of formal methods

    Bjørner, Dines; Havelund, Klaus


    -oriented methods to analysis-oriented methods. Then, Sect. 2, we shall provide a "survey": which are the 'prerequisite works' that have enabled formal methods, Sect. 2.1, and which are, to us, the, by now, classical 'formal methods', Sect. 2.2. We then ask ourselves the question: have formal methods for software......" is complemented, in Sect. 3.4, by a "looking forward" at some promising developments-besides the alleviation of the (eighth or more) hindrances! © 2014 Springer International Publishing Switzerland....

  9. Mixed Method Research: An Overview

    Dewan Mahboob HOSSAIN


    Full Text Available This article gives a general overview of mixed method research. In mixed method, the researchers combine both qualitative and quantitative approaches in a single research project. The article first attempts to define mixed method research. Then it gives a comparison of qualitative and quantitative approaches. It also introduces the well-known controversy among the researchers: which of these approaches is superior? By explaining this controversy, the article identifies the need for mixed method research. Lastly, the article describes the process of mixed method research.

  10. Overview of paint removal methods

    Foster, Terry


    With the introduction of strict environmental regulations governing the use and disposal of methylene chloride and phenols, major components of chemical paint strippers, there have been many new environmentally safe and effective methods of paint removal developed. The new methods developed for removing coatings from aircraft and aircraft components include: mechanical methods using abrasive media such as plastic, wheat starch, walnut shells, ice and dry ice, environmentally safe chemical strippers and paint softeners, and optical methods such as lasers and flash lamps. Each method has its advantages and disadvantages, and some have unique applications. For example, mechanical and abrasive methods can damage sensitive surfaces such as composite materials and strict control of blast parameters and conditions are required. Optical methods can be slow, leaving paint residues, and chemical methods may not remove all of the coating or require special coating formulations to be effective. As an introduction to environmentally safe and effective methods of paint removal, this paper is an overview of the various methods available. The purpose of this overview is to introduce the various paint removal methods available.

  11. Method of making alkyl esters

    Elliott, Brian


    Methods of making alkyl esters are described herein. The methods are capable of using raw, unprocessed, low-cost feedstocks and waste grease. Generally, the method involves converting a glyceride source to a fatty acid composition and esterifying the fatty acid composition to make alkyl esters. In an embodiment, a method of making alkyl esters comprises providing a glyceride source. The method further comprises converting the glyceride source to a fatty acid composition comprising free fatty acids and less than about 1% glyceride by mass. Moreover, the method comprises esterifying the fatty acid composition in the presence of a solid acid catalyst at a temperature ranging firm about C. to about C. to produce alkyl esters, such that at least 85% of the free fatty acids are converted to alkyl esters. The method also incorporates the use of packed bed reactors for glyceride conversion and/or fatty acid esterification to make alkyl esters.

  12. An Extended Keyword Extraction Method

    Hong, Bao; Zhen, Deng

    Among numerous Chinese keyword extraction methods, Chinese characteristics were shortly considered. This phenomenon going against the precision enhancement of the Chinese keyword extraction. An extended term frequency based method(Extended TF) is proposed in this paper which combined Chinese linguistic characteristics with basic TF method. Unary, binary and ternary grammars for the candidate keyword extraction as well as other linguistic features were all taken into account. The method establishes classification model using support vector machine. Tests show that the proposed extraction method improved key words precision and recall rate significantly. We applied the key words extracted by the extended TF method into the text file classification. Results show that the key words extracted by the proposed method contributed greatly to raising the precision of text file classification.

  13. Compositions, antibodies, asthma diagnosis methods, and methods for preparing antibodies

    Jin, Hongjun; Zangar, Richard C.


    Methods for preparing an antibody are provided with the method including incorporating 3-bromo-4-hydroxy-benzoic acid into a protein to form an antigen, immunizing a mammalian host with the antigen, and recovering an antibody having an affinity for the antigen from the host. Antibodies having a binding affinity for a monohalotyrosine are provided as well as composition comprising an antibody bound with monohalotyrosine. Compositions comprising a protein having a 3-bromo-4-hydroxy-benzoic acid moiety are also provided. Methods for evaluating the severity of asthma are provide with the methods including analyzing sputum of a patient using an antibody having a binding affinity for monohalotyrosine, and measuring the amount of antibody bound to protein. Methods for determining eosinophil activity in bodily fluid are also provided with the methods including exposing bodily fluid to an antibody having a binding affinity for monohalotyrosine, and measuring the amount of bound antibody to determine the eosinophil activity.

  14. User interface inspection methods a user-centered design method

    Wilson, Chauncey


    User Interface Inspection Methods succinctly covers five inspection methods: heuristic evaluation, perspective-based user interface inspection, cognitive walkthrough, pluralistic walkthrough, and formal usability inspections. Heuristic evaluation is perhaps the best-known inspection method, requiring a group of evaluators to review a product against a set of general principles. The perspective-based user interface inspection is based on the principle that different perspectives will find different problems in a user interface. In the related persona-based inspection, colleagues assume the

  15. The Monte Carlo method the method of statistical trials

    Shreider, YuA


    The Monte Carlo Method: The Method of Statistical Trials is a systematic account of the fundamental concepts and techniques of the Monte Carlo method, together with its range of applications. Some of these applications include the computation of definite integrals, neutron physics, and in the investigation of servicing processes. This volume is comprised of seven chapters and begins with an overview of the basic features of the Monte Carlo method and typical examples of its application to simple problems in computational mathematics. The next chapter examines the computation of multi-dimensio

  16. From the scientific method to the clinical method: theoretical considerations

    Roberto Hernández Hernández


    Full Text Available The scientific method is a general method composed of several stages necessary for the development of any scientific research. It is the focus to approach reality and to study natural phenomenon, reality itself and thoughts in order to find their essence and interrelationships. The clinical method is the particular application of the scientific method and in the present economic conditions its use is crucial because of the advantages that it reports from this point of view, as well as for the wellbeing of the patient.

  17. Efficient and accurate fragmentation methods.

    Pruitt, Spencer R; Bertoni, Colleen; Brorsen, Kurt R; Gordon, Mark S


    Conspectus Three novel fragmentation methods that are available in the electronic structure program GAMESS (general atomic and molecular electronic structure system) are discussed in this Account. The fragment molecular orbital (FMO) method can be combined with any electronic structure method to perform accurate calculations on large molecular species with no reliance on capping atoms or empirical parameters. The FMO method is highly scalable and can take advantage of massively parallel computer systems. For example, the method has been shown to scale nearly linearly on up to 131 000 processor cores for calculations on large water clusters. There have been many applications of the FMO method to large molecular clusters, to biomolecules (e.g., proteins), and to materials that are used as heterogeneous catalysts. The effective fragment potential (EFP) method is a model potential approach that is fully derived from first principles and has no empirically fitted parameters. Consequently, an EFP can be generated for any molecule by a simple preparatory GAMESS calculation. The EFP method provides accurate descriptions of all types of intermolecular interactions, including Coulombic interactions, polarization/induction, exchange repulsion, dispersion, and charge transfer. The EFP method has been applied successfully to the study of liquid water, π-stacking in substituted benzenes and in DNA base pairs, solvent effects on positive and negative ions, electronic spectra and dynamics, non-adiabatic phenomena in electronic excited states, and nonlinear excited state properties. The effective fragment molecular orbital (EFMO) method is a merger of the FMO and EFP methods, in which interfragment interactions are described by the EFP potential, rather than the less accurate electrostatic potential. The use of EFP in this manner facilitates the use of a smaller value for the distance cut-off (Rcut). Rcut determines the distance at which EFP interactions replace fully quantum

  18. Analytical Method Development & Validation for Related Substances Method of Busulfan Injection by Ion Chromatography Method

    Rewaria S


    Full Text Available A new simple, accurate, precise and reproducible Ion chromatography method has been developed forthe estimation of Methane sulfonic acid in Busulfan injectable dosage. The method which is developedis also validated in complete compliance with the current regulatory guidelines by using well developedanalytical method validation techniques and tools which comprises with the analytical method validationparameters like Linearity, LOD and LOQ determination, Accuracy, Method precision, Specificity,System suitability, Robustness, Ruggedness etc. by adopting the current method the linearity obtained isnear to 0.999 and thus this shows that the method is capable to give a good detector response, therecovery calculated was within the range of 85% to 115% of the specification limits.

  19. Numerical methods for phase retrieval

    Osherovich, Eliyahu


    In this work we consider the problem of reconstruction of a signal from the magnitude of its Fourier transform, also known as phase retrieval. The problem arises in many areas of astronomy, crystallography, optics, and coherent diffraction imaging (CDI). Our main goal is to develop an efficient reconstruction method based on continuous optimization techniques. Unlike current reconstruction methods, which are based on alternating projections, our approach leads to a much faster and more robust method. However, all previous attempts to employ continuous optimization methods, such as Newton-type algorithms, to the phase retrieval problem failed. In this work we provide an explanation for this failure, and based on this explanation we devise a sufficient condition that allows development of new reconstruction methods---approximately known Fourier phase. We demonstrate that a rough (up to $\\pi/2$ radians) Fourier phase estimate practically guarantees successful reconstruction by any reasonable method. We also pres...

  20. The Plastic Tension Field Method

    Hansen, Thomas


    . The emphasis is attached to the presentation of a design method based on the diagonal tension field theory. Also, how to determine the load-carrying capacity of a given steel plate girder with transverse web stiffeners, is briefly presented. The load-carrying capacity may be predicted by applying both...... method. The method is based on the theory of plasticity and is analogous to the so-called diagonal compression field method developed for reinforced concrete beams with transverse stirrups, which is adopted in the common European concrete code (Eurocode 2). Many other theories have been developed......, but the method presented differs from these theories by incorporating the strength of the transverse stiffeners and by the assumption that the tensile bands may pass the transverse stiffeners, which often is observed in tests. Other methods have only dealt with a single web field between two stiffeners...

  1. "Phenomenology" and qualitative research methods.

    Nakayama, Y


    Phenomenology is generally based on phenomenological tradition from Husserl to Heidegger and Merleau-Ponty. As philosophical stances provide the assumptions in research methods, different philosophical stances produce different methods. However, the term "phenomenology" is used in various ways without the definition being given, such as phenomenological approach, phenomenological method, phenomenological research, etc. The term "phenomenology" is sometimes used as a paradigm and it is sometimes even viewed as synonymous with qualitative methods. As a result, the term "phenomenology" leads to conceptual confusions in qualitative research methods. The purpose of this paper is to examine the term "phenomenology" and explore philosophical assumptions, and discuss the relationship between philosophical stance and phenomenology as a qualitative research method in nursing.

  2. Negotiating a Systems Development Method

    Karlsson, Fredrik; Hedström, Karin

    Systems development methods (or methods) are often applied in tailored version to fit the actual situation. Method tailoring is in most the existing literature viewed as either (a) a highly rational process with the method engineer as the driver where the project members are passive information providers or (b) an unstructured process where the systems developer makes individual choices, a selection process without any driver. The purpose of this chapter is to illustrate that important design decisions during method tailoring are made by project members through negotiation. The study has been carried out using the perspective of actor-network theory. Our narratives depict method tailoring as more complex than (a) and (b) show the driver role rotates between the project members, and design decisions are based on influences from several project members. However, these design decisions are not consensus decisions.

  3. Monte Carlo methods for electromagnetics

    Sadiku, Matthew NO


    Until now, novices had to painstakingly dig through the literature to discover how to use Monte Carlo techniques for solving electromagnetic problems. Written by one of the foremost researchers in the field, Monte Carlo Methods for Electromagnetics provides a solid understanding of these methods and their applications in electromagnetic computation. Including much of his own work, the author brings together essential information from several different publications.Using a simple, clear writing style, the author begins with a historical background and review of electromagnetic theory. After addressing probability and statistics, he introduces the finite difference method as well as the fixed and floating random walk Monte Carlo methods. The text then applies the Exodus method to Laplace's and Poisson's equations and presents Monte Carlo techniques for handing Neumann problems. It also deals with whole field computation using the Markov chain, applies Monte Carlo methods to time-varying diffusion problems, and ...

  4. Methods of rock burst prediction

    Genkin, V.A.; Minin, Yu.Ya.; Morozov, G.D.; Proskuryakov, V.M.; Cmirnov, V.A.


    Some methods of predicting rock bursts in underground coal and iron ore mines are evaluated: using BP-18 indenters and the MGD indenter with automatic recording; seismic method consisting in measuring the speed of shock waves travelling through various layers (apparatus SB-20 is designed for use in coal mines); electrometric method (measuring resistance between two electrodes when electric currents flow through coal and rocks). The design of the AEhSSh-1 measuring instrument, used in the electrometric method in coal mines is also described. Each of the methods is described and mathematical fomulae used as their theoretical basis are presented. The calculating process is explained and brief information on the design and use of the measuring instrument is given. The methods are evaluated from the viewpoint of precision. (In Russian)

  5. Microencapsulation and Electrostatic Processing Method

    Morrison, Dennis R. (Inventor); Mosier, Benjamin (Inventor)


    Methods are provided for forming spherical multilamellar microcapsules having alternating hydrophilic and hydrophobic liquid layers, surrounded by flexible, semi-permeable hydrophobic or hydrophilic outer membranes which can be tailored specifically to control the diffusion rate. The methods of the invention rely on low shear mixing and liquid-liquid diffusion process and are particularly well suited for forming microcapsules containing both hydrophilic and hydrophobic drugs. These methods can be carried out in the absence of gravity and do not rely on density-driven phase separation, mechanical mixing or solvent evaporation phases. The methods include the process of forming, washing and filtering microcapsules. In addition, the methods contemplate coating microcapsules with ancillary coatings using an electrostatic field and free fluid electrophoresis of the microcapsules. The microcapsules produced by such methods are particularly useful in the delivery of pharmaceutical compositions.

  6. Reflexive Learning through Visual Methods

    Frølunde, Lisbeth


    What. This chapter concerns how visual methods and visual materials can support visually oriented, collaborative, and creative learning processes in education. The focus is on facilitation (guiding, teaching) with visual methods in learning processes that are designerly or involve design. Visual...... methods are exemplified through two university classroom cases about collaborative idea generation processes. The visual methods and materials in the cases are photo elicitation using photo cards, and modeling with LEGO Serious Play sets. Why. The goal is to encourage the reader, whether student...... or professional, to facilitate with visual methods in a critical, reflective, and experimental way. The chapter offers recommendations for facilitating with visual methods to support playful, emergent designerly processes. The chapter also has a critical, situated perspective. Where. This chapter offers case...

  7. Shuttle onboard IMU alignment methods

    Henderson, D. M.


    The current approach to the shuttle IMU alignment is based solely on the Apollo Deterministic Method. This method is simple, fast, reliable and provides an accurate estimate for the present cluster to mean of 1,950 transformation matrix. If four or more star sightings are available, the application of least squares analysis can be utilized. The least squares method offers the next level of sophistication to the IMU alignment solution. The least squares method studied shows that a more accurate estimate for the misalignment angles is computed, and the IMU drift rates are a free by-product of the analysis. Core storage requirements are considerably more; estimated 20 to 30 times the core required for the Apollo Deterministic Method. The least squares method offers an intermediate solution utilizing as much data that is available without a complete statistical analysis as in Kalman filtering.

  8. Automated methods of corrosion measurement

    Andersen, Jens Enevold Thaulov; Bech-Nielsen, Gregers; Reeve, John Ch


    Measurements of corrosion rates and other parameters connected with corrosion processes are important, first as indicators of the corrosion resistance of metallic materials and second because such measurements are based on general and fundamental physical, chemical, and electrochemical relations....... Hence improvements and innovations in methods applied in corrosion research are likeliy to benefit basic disciplines as well. A method for corrosion measurements can only provide reliable data if the beckground of the method is fully understood. Failure of a method to give correct data indicates a need...... to revise assumptions regarding the basis of the method, which sometimes leads to the discovery of as-yet unnoticed phenomena. The present selection of automated methods for corrosion measurements is not motivated simply by the fact that a certain measurement can be performed automatically. Automation...

  9. Mixed methods in gerontological research.

    Happ, Mary Beth


    This article distinguishes between parallel and integrated mixed methods research approaches. Barriers to integrated mixed methods approaches in gerontological research are discussed and critiqued. The author presents examples of mixed methods gerontological research to highlight approaches to data integration at the levels of data analysis, interpretation, and research reporting. As a summary of the methodological literature, four basic levels of mixed methods data combination are proposed. Opportunities for mixing qualitative and quantitative data are explored using contemporary examples from published studies. Data transformation and visual display, judiciously applied, are proposed as pathways to fuller mixed methods data integration and analysis. Finally, practical strategies for mixing qualitative and quantitative data types are explicated, as gerontological research moves beyond parallel mixed methods approaches to achieve data integration.

  10. A Moral Method? Thoughts on Cultivating Empathy through Method Acting.

    Verducci, Susan


    Using Nel Noddings ethic of Care, contends that this model of empathy has elements in common with the type of empathy method actors employ. Discusses the agreements between Caring's empathy and dramatic empathy focusing on three skills method actors use and the three differences that possess moral implications. (CMK)

  11. Mapping Mixed Methods Research: Methods, Measures, and Meaning

    Wheeldon, J.


    This article explores how concept maps and mind maps can be used as data collection tools in mixed methods research to combine the clarity of quantitative counts with the nuance of qualitative reflections. Based on more traditional mixed methods approaches, this article details how the use of pre/post concept maps can be used to design qualitative…

  12. Sur Quatre Methodes Audio-Visuelles (On Four Audiovisual Methods)

    Porquier, Remy; Vives, Robert


    This is a critical examination of four audiovisual methods for the teaching of French as a Foreign Language. The methods have as a common basis the interrelationship of image, dialogue, situation, and give grammar priority over vocabulary. (Text is in French.) (AM)

  13. Method of manufacturing superconductor wire

    Motowidlo, Leszek


    A method for forming Nb.sub.3Sn superconducting wire is provided. The method employs a powder-in-tube process using a high-tin intermetallic compound, such as MnSn.sub.2, for producing the Nb.sub.3Sn. The use of a high-tin intermetallic compound enables the process to perform hot extrusion without melting the high-tin intermetallic compound. Alternatively, the method may entail drawing the wire without hot extrusion.

  14. Regression methods for medical research

    Tai, Bee Choo


    Regression Methods for Medical Research provides medical researchers with the skills they need to critically read and interpret research using more advanced statistical methods. The statistical requirements of interpreting and publishing in medical journals, together with rapid changes in science and technology, increasingly demands an understanding of more complex and sophisticated analytic procedures.The text explains the application of statistical models to a wide variety of practical medical investigative studies and clinical trials. Regression methods are used to appropriately answer the

  15. Local method for detecting communities

    Bagrow, James P.; Bollt, Erik M.


    We propose a method of community detection that is computationally inexpensive and possesses physical significance to a member of a social network. This method is unlike many divisive and agglomerative techniques and is local in the sense that a community can be detected within a network without requiring knowledge of the entire network. A global application of this method is also introduced. Several artificial and real-world networks, including the famous Zachary karate club, are analyzed.

  16. A Voltage Quality Detection Method

    Chen, Zhe; Wei, Mu


    This paper presents a voltage quality detection method based on a phase-locked loop (PLL) technique. The technique can detect the voltage magnitude and phase angle of each individual phase under both normal and fault power system conditions. The proposed method has the potential to evaluate various...... power quality disturbances, such as interruptions, sags and imbalances. Simulation studies have been performed. The effectiveness of the proposed method has been demonstrated under the simulated typical power disturbances....

  17. Bayesian Methods for Statistical Analysis

    Puza, Borek


    Bayesian methods for statistical analysis is a book on statistical methods for analysing a wide variety of data. The book consists of 12 chapters, starting with basic concepts and covering numerous topics, including Bayesian estimation, decision theory, prediction, hypothesis testing, hierarchical models, Markov chain Monte Carlo methods, finite population inference, biased sampling and nonignorable nonresponse. The book contains many exercises, all with worked solutions, including complete c...

  18. Chebyshev and Fourier spectral methods

    Boyd, John P


    Completely revised text focuses on use of spectral methods to solve boundary value, eigenvalue, and time-dependent problems, but also covers Hermite, Laguerre, rational Chebyshev, sinc, and spherical harmonic functions, as well as cardinal functions, linear eigenvalue problems, matrix-solving methods, coordinate transformations, methods for unbounded intervals, spherical and cylindrical geometry, and much more. 7 Appendices. Glossary. Bibliography. Index. Over 160 text figures.

  19. Mixed Method Research: An Overview

    Hossain, Dewan Mahboob


    This article gives a general overview of mixed method research. In mixed method, the researchers combine both qualitative and quantitative approaches in a single research project. The article first attempts to define mixed method research. Then it gives a comparison of qualitative and quantitative approaches. It also introduces the well-known controversy among the researchers: which of these approaches is superior? By explaining this controversy, the article identifies the need for mixed meth...

  20. Transport methods for energetic particles

    WuHong-Lu; YangChui-Hsu


    In order to estimate radiation risk assessment for astronaut's radiation safety in space activities.transport codes for high energy particles have been created.Two of the transport methods,perturbation and Green function methods,for high energy particles are reviewed in this paper,and some of the calculated results with the perturbation method are presented.Finally,the low energy transport in the regard of the biological effects by low energy ions in also briefly discussed.

  1. Entropy-based benchmarking methods


    We argue that benchmarking sign-volatile series should be based on the principle of movement and sign preservation, which states that a bench-marked series should reproduce the movement and signs in the original series. We show that the widely used variants of Denton (1971) method and the growth preservation method of Causey and Trager (1981) may violate this principle, while its requirements are explicitly taken into account in the pro-posed entropy-based benchmarking methods. Our illustrati...

  2. Methods for Precise Submesh Allocation

    Craig Morgenstern


    Full Text Available In this article we describe and compare several recently proposed algorithms for precise submesh allocation in a two-dimensional mesh connected system. The methods surveyed include various frame sliding strategies, the maximum boundary value heuristic, and interval set scan techniques. In addition, a new enhancement to the interval set scan method is described. This enhancement results in an algorithm that has better allocation and run-time performance under a FCFS scheduling policy than any of the other proposed methods. We present results drawn from an extensive simulation study to illustrate the relative efficiency of the various methods.

  3. Methods for Predicting Stock Indexes

    Martha Cecilia García


    Full Text Available This paper presents a literature review on methods that have been used in the last two decades to predict Stock Market Indexes. Methods studied range from those enabling to grab the linear characteristics present in the stock market indexes, going through those that focus on non-linear features and finally hybrid methods that are more robust, since they capture linear and non-linear features. In addition, this research includes methods that use macroeconomic variables to predict indexes from different stock exchanges around the world.

  4. Effectiveness of Family Planning Methods

    ... effective, temporary method of contraception. Emergency Contraception: Emergency contraceptive pills or a copper IUD after unprotected intercourse substantially reduces risk of pregnancy. Adapted from World Health Organization (WHO) ...

  5. Metathesis catalysts and methods thereof

    Schrock, Richard Royce; Yuan, Jian


    The present application provides, among other things, novel compounds for metathesis reactions, and methods for preparing and using provided compounds. In some embodiments, the present invention provides compounds having the structure of formula I or II. In some embodiments, the present invention provides methods for preparing a compound of formula I or II. In some embodiments, the present invention provides methods for using a provided compound. In some embodiments, a provided compound is useful for stereoselective ring-opening metathesis polymerization. In some embodiments, a provided metathesis method provides cis and/or isotactic polymers.

  6. Comparison of photopeak integration methods

    Kennedy, G.


    Several methods for the calculation of gamma-ray photopeak areas have been compared for the case of a small peak on a high Compton background. 980 similar spectra were accumulated with a germanium detector using a weak 137Cs source to produce a peak at 662 keV on a Compton background generated by a 60Co source. A computer program was written to calculate the area of the 662 keV peak using the total- and partial-peak-area methods, a modification of Sterlinski's method, Loska's method and least-squares fitting of Gaussian peak shapes with linear and quadratic background. The precision attained was highly dependent on the number of channels used to estimate the background, and the best precision, about 9.5%, was obtained with the partial-peak-area method, the modified Sterlinski method and least-squares fitting with variable peak position, fixed peak width and linear background. The methods were also evaluated for their sensitivity to uncertainty in the peak centroid position. Considering precision, ease of use, reliability and universal applicability, the total-peak-area method using several channels for background estimation and the least-squares-fitting method are recommended.

  7. Comparison of photopeak integration methods

    Kennedy, G. (Ecole Polytechnique, Montreal, PQ (Canada). Energy Engineering Inst.)


    Several methods for the calculation of gamma-ray photopeak areas have been compared for the case of a small peak on a high Compton background. 980 similar spectra were accumulated with a germanium detector using a weak {sup 137}Cs source to produce a peak at 662 keV on a Compton background generated by a {sup 60}Co source. A computer program was written to calculate the area of the 662 keV peak using the total- and partial-peak-area methods, a modification of Sterlinski's method, Loska's method and least-squares fitting of Gaussian peak shapes with linear and quadratic background. The precision attained was highly dependent on the number of channels used to estimate the background, and the best precision, about 9.5%, was obtained with the partial-peak-area method, the modified Sterlinski method and least-squares fitting with variable peak position, fixed peak width and linear background. The methods were also evaluated for their sensitivity to uncertainty in the peak centroid position. Considering precision, ease of use, reliability and universal applicability, the total-peak-area method using several channels for background estimation and the least-squares-fitting method are recommended. (orig.).

  8. Quantitative vs qualitative research methods.

    Lakshman, M; Sinha, L; Biswas, M; Charles, M; Arora, N K


    Quantitative methods have been widely used because of the fact that things that can be measured or counted gain scientific credibility over the unmeasurable. But the extent of biological abnormality, severity, consequences and the impact of illness cannot be satisfactorily captured and answered by the quantitative research alone. In such situations qualitative methods take a holistic perspective preserving the complexities of human behavior by addressing the "why" and "how" questions. In this paper an attempt has been made to highlight the strengths and weaknesses of both the methods and also that a balanced mix of both qualitative as well as quantitative methods yield the most valid and reliable results.

  9. Optimization of Medical Teaching Methods

    Wang Fei


    Full Text Available In order to achieve the goal of medical education, medicine and adapt to changes in the way doctors work, with the rapid medical teaching methods of modern science and technology must be reformed. Based on the current status of teaching in medical colleges method to analyze the formation and development of medical teaching methods, characteristics, about how to achieve optimal medical teaching methods for medical education teachers and management workers comprehensive and thorough change teaching ideas and teaching concepts provide a theoretical basis.

  10. Methods for Obfuscating Java Programs

    Florin Buzatu


    Full Text Available Java programs distributed through internet are suffering of problems like reverse engineering, algorithms theft and unauthorized functional changes. The reason for this issue is that the bytecode from Java class file holds enough information to be decompiled into source code that resembles the original. In this paper, I discuss some practical obfuscation methods that make difficult the understanding of the decompiled programs. The methods analyzed are: lexical obfuscation, data obfuscation, control flow obfuscation, obfuscation methods that make use of the discrepancy between bytecode and source code. In order to evaluate the usefulness of these methods, some metrics will be described.

  11. Methods in Logic Based Control

    Christensen, Georg Kronborg


    Desing and theory of Logic Based Control systems.Boolean Algebra, Karnaugh Map, Quine McClusky's algorithm. Sequential control design. Logic Based Control Method, Cascade Control Method. Implementation techniques: relay, pneumatic, TTL/CMOS,PAL and PLC- and Soft_PLC implementation. PLC-design met......Desing and theory of Logic Based Control systems.Boolean Algebra, Karnaugh Map, Quine McClusky's algorithm. Sequential control design. Logic Based Control Method, Cascade Control Method. Implementation techniques: relay, pneumatic, TTL/CMOS,PAL and PLC- and Soft_PLC implementation. PLC...

  12. Statistical Methods for Evolutionary Trees

    Edwards, A. W. F.


    In 1963 and 1964, L. L. Cavalli-Sforza and A. W. F. Edwards introduced novel methods for computing evolutionary trees from genetical data, initially for human populations from blood-group gene frequencies. The most important development was their introduction of statistical methods of estimation applied to stochastic models of evolution.

  13. Method selection in adaptation research

    Werners, Saskia Elisabeth; Loon-Steensma, van Jantsje Mintsje; Oost, Albert Peter


    Many methods are available to support adaptation planning. Yet there is little guidance on their selection. A recently developed diagnostic framework offers a structured set of criteria to choose research methods for specific adaptation questions. It has been derived from science-driven cases mos

  14. Electrochemical method for transferring graphene


    The present application discloses a method for separating a graphene-support layer laminate from a conducting substrate-graphene-support layer laminate, using a gentle, controllable electrochemical method. In this way, substrates which are fragile, expensive or difficult to manufacture can be used...

  15. Methods of synthesizing thermoelectric materials

    Ren, Zhifeng; Chen, Shuo; Liu, Wei-Shu; Wang, Hengzhi; Wang, Hui; Yu, Bo; Chen, Gang


    Methods for synthesis of thermoelectric materials are disclosed. In some embodiments, a method of fabricating a thermoelectric material includes generating a plurality of nanoparticles from a starting material comprising one or more chalcogens and one or more transition metals; and consolidating the nanoparticles under elevated pressure and temperature, wherein the nanoparticles are heated and cooled at a controlled rate.

  16. Preparation methods of alginate nanoparticles

    Paques, J.P.; Linden, van der E.; Rijn, van C.J.M.; Sagis, L.M.C.


    This article reviews available methods for the formation of alginate nano-aggregates, nanocapsules and nanospheres. Primarily, alginate nanoparticles are being prepared by two methods. In the “complexation method”, complex formation on the interface of an oil droplet is used to form alginate nanocap

  17. Recent Progress of Thioester Method


    @@ Introduction The availability of site-specifically modified peptides is of vitalimportance for biochemical and biophysical studies. Biological methods, such as expression using bacteria, are useful. They are, however, not always applicable to the synthesis of peptides with sitespecific modifications. Chemical methods can be viable alternatives to those biological approaches.

  18. Looking back: the Delft method

    Makkink, H.


    One of the more unexpected innovations to come out of Delft is an unconventional method for teaching a second language. Developed 25 years ago by the applied linguistics section, the Delft method has proved highly effective, provided, that is, the students do their homework. You learn a language by

  19. Fluorescence nanoscopy. Methods and applications

    Requejo-Isidro, Jose


    Fluorescence nanoscopy refers to the experimental techniques and analytical methods used for fluorescence imaging at a resolution higher than conventional, diffraction-limited, microscopy. This review explains the concepts behind fluorescence nanoscopy and focuses on the latest and promising developments in acquisition techniques, labelling strategies to obtain highly detailed super-resolved images and in the quantitative methods to extract meaningful information from them.

  20. Mixed-Methods Research Methodologies

    Terrell, Steven R.


    Mixed-Method studies have emerged from the paradigm wars between qualitative and quantitative research approaches to become a widely used mode of inquiry. Depending on choices made across four dimensions, mixed-methods can provide an investigator with many design choices which involve a range of sequential and concurrent strategies. Defining…

  1. The mGPC method:

    Glückstad, Jesper; Palima, Darwin


    We adapt concepts from matched filtering to propose a method for generating rapidly reconfigurable multiple beams. As a phase-only spatially filtering extension of the Generalized Phase Contrast (GPC) technique, the proposed method coined mGPC can yield dynamically reconfigurable optical beam arr...... arrays with high light efficiency for optical manipulation, high-speed sorting and other parallel spatial light applications [1]....

  2. Bioluminescence methods for enzymatic determinations

    Bostick, William D.; Denton, Mark S.; Dinsmore, Stanley R.


    An enzymatic method for continuous, on-line and rapid detection of diagnostically useful biomarkers, which are symptomatic of disease or trauma-related tissue damage, is disclosed. The method is characterized by operability on authentic samples of complex biological fluids which contain the biomarkers.

  3. Laboratory method used for bioremediation

    Carman, M. Leslie; Taylor, Robert T.


    An improved method for in situ microbial filter bioremediation having increasingly operational longevity of an in situ microbial filter emplaced into an aquifer. A method for generating a microbial filter of sufficient catalytic density and thickness, which has increased replenishment interval, improved bacteria attachment and detachment characteristics and the endogenous stability under in situ conditions. A system for in situ field water remediation.

  4. Forecasting Using Random Subspace Methods

    T. Boot (Tom); D. Nibbering (Didier)


    textabstractRandom subspace methods are a novel approach to obtain accurate forecasts in high-dimensional regression settings. We provide a theoretical justification of the use of random subspace methods and show their usefulness when forecasting monthly macroeconomic variables. We focus on two appr

  5. Method of making optoelectric devices


    A method of preparing an optoelectric device, comprising: (a) providing a substrate on which is formed a first electrode layer; (b) forming an electron transport layer according to the following method: i) forming a film of a coating ink comprising zinc acetate in aqueous solution; ii) drying...

  6. Sometimes "Newton's Method" Always "Cycles"

    Latulippe, Joe; Switkes, Jennifer


    Are there functions for which Newton's method cycles for all non-trivial initial guesses? We construct and solve a differential equation whose solution is a real-valued function that two-cycles under Newton iteration. Higher-order cycles of Newton's method iterates are explored in the complex plane using complex powers of "x." We find a class of…

  7. Psychological Autopsies: Methods and Ethics.

    Beskow, Jan; And Others


    Discusses methodological and ethical issues pertaining to "psychological autopsy," an interview method for reconstruction of suicidal death through interviews with survivors, based on application of method to three studies of suicides and review of other investigations. Emphasizes consideration of integrity of deceased, integrity and health of…

  8. Statistical methods for evolutionary trees.

    Edwards, A W F


    In 1963 and 1964, L. L. Cavalli-Sforza and A. W. F. Edwards introduced novel methods for computing evolutionary trees from genetical data, initially for human populations from blood-group gene frequencies. The most important development was their introduction of statistical methods of estimation applied to stochastic models of evolution.

  9. Formal Methods: Practice and Experience

    Woodcock, Jim; Larsen, Peter Gorm; Bicarregui, Juan


    Formal methods use mathematical models for analysis and verification at any part of the program life-cycle. We describe the state of the art in the industrial use of formal methods, concentrating on their increasing use at the earlier stages of specification and design. We do this by reporting on...

  10. Comparison between parallel transfer matrix method and admittance sum method.

    Verdière, Kévin; Panneton, Raymond; Elkoun, Saïd; Dupont, Thomas; Leclaire, Philippe


    A transfer matrix method to predict absorption coefficient and transmission loss of parallel assemblies of materials which can be expressed by a 2 × 2 transfer matrix was published recently. However, the usual method based on the sum of admittances is largely used to predict also surface admittance of parallel assemblies. This paper aims to highlight differences between both methods through three examples on a parallel assembly backed by (1) a rigid wall, (2) an air cavity, and (3) an anechoic termination.

  11. Transformation method and wave control

    Chang, Zheng; Hu, Jin; Hu, Geng-Kai


    Transformation method provides an efficient way to control wave propagation by materials. The transformed relations for field and material during a transformation are essential to fulfill this method. We propose a systematic method to derive the transformed relations for a general physic process, the constraint conditions are obtained by considering geometrical and physical constraint during a mapping. The proposed method is applied to Navier's equation for elastodynamics, Helmholtz's equation for acoustic wave and Maxwell's equation for electromagnetic wave, the corresponding transformed relations are derived, which can be used in the framework of transformation method for wave control. We show that contrary to electromagnetic wave, the transformed relations are not uniquely determined for elastic wave and acoustic wave, so we have a freedom to choose them differently. Using the obtained transformed relations, we also provide some examples for device design, a concentrator for elastic wave, devices for illusion acoustic and illusion optics are conceived and validated by numerical simulations.

  12. Meshless Methods in Solid Mechanics

    Chen, Youping; Eskandarian, Azim


    Finite element method has been the dominant technique in computational mechanics in the past decades, and it has made significant contributions to the developments in engineering and science. Nevertheless, finite element method is not well suited to problems having severe mesh distortion owing to extremely large deformations of materials, encountering moving discontinuities such as crack propagation along arbitrary and complex paths, involving considerable meshing and re-meshing in structural optimization problems, or having multidomain of influence in multi-phenomenon physical problems. It is impossible to completely overcome those mesh-related difficulties by a mesh-based method. The highly structured nature of finite element approximations imposes severe penalties in the solutions of those problems. Distinguishing with finite element, finite difference and finite volume methods, meshless method discretizes the continuum body only with a set of nodal points and the approximation is constructed entirely in t...

  13. Approximation methods in probability theory

    Čekanavičius, Vydas


    This book presents a wide range of well-known and less common methods used for estimating the accuracy of probabilistic approximations, including the Esseen type inversion formulas, the Stein method as well as the methods of convolutions and triangle function. Emphasising the correct usage of the methods presented, each step required for the proofs is examined in detail. As a result, this textbook provides valuable tools for proving approximation theorems. While Approximation Methods in Probability Theory will appeal to everyone interested in limit theorems of probability theory, the book is particularly aimed at graduate students who have completed a standard intermediate course in probability theory. Furthermore, experienced researchers wanting to enlarge their toolkit will also find this book useful.

  14. Creativity Methods in Interaction Design

    Biskjaer, Michael Mose; Dalsgaard, Peter; Halskov, Kim


    The field of interaction design encompasses a variety of methods for fostering innovation and creativity. In this paper, we present a selection of such methods that scaffold ideation and concept development in the early phases of design. As a conceptual frame for discussing these methods, we...... introduce four aspects that are particularly salient in the field of interaction design: tradition and transcendence, convergence and divergence, degree of structure, and sources of inspiration. We then outline how the methods relate to each of these aspects. The paper contributes to design practitioners...... by providing an overview of the methods and insights into when and how they may be employed to foster creativity and innovation in the design process; with regards to design research, the main contribution of the paper lies in the establishment and discussion of the four aspects as a frame for analyzing...

  15. Teaching methods: Tradition and innovation

    Nikandrov, Nikolai D.


    It has always been difficult to distinguish between tradition and innovation in teaching methods, not least because of the absence of clear-cut criteria. Definitions of teaching methods are also loose rather than binding. Nevertheless a trend towards active participation by studients is noticeable and very often taken as marking `progressive' teaching. Starting from the basic relationship of method and objective, an attempt is made to further relate cognitive activity of students to specific levels of achievement which are considered as teaching objectives. It is suggested, too, that a loose notion of method can for practical purposes be replaced by a more reliable notion of teaching text whether presented orally or given in written form. Then the problem of innovation in teaching methods can be stated a bit more precisely as that of creating a good teaching text. Some suggestions of how this can be achieved are discussed.


    Huan-RueiShiu; Feng-ChuOu; Sih-LiChen


    A new 3C duct design method is proposed for designing a high quality, energy-efficiency cost-effective air duct system. It not only considers the demand of volume flow rate, but also takes into consideration a number of issues including system pressure balance, noise, vibration, space limitation and total system cost. This new method comprises three major calculation procedures:initial computer-aided design (CAD), computer-aided simulation (CAS) and correction processes (CP). An example is presented in this study to understand the characteristics of 3C method. It shows that 3C duct design method provides a simple computation procedure for an optimum air duct system. It also shortens the design schedule, prevents human calculation errors, and reduces the dependence on designer experience. In addition to apply in a new duct system design, 3C duct design method is also a powerful design tool for the expansion of an existing duct system.

  17. Radioreceptor assay method for insulin

    Mori, K.F.; Wood, R.J. (Bureau of Drug Research, Health and Welfare Canada, Ottawa, Ontario. Health Protection Branch)


    A sensitive practical radioreceptor assay method for pharmaceutical insulin products has been developed with partially purified rat liver plasma membranes and the optimal conditions under which the best overall assay performance is obtainable have been defined. Intra- and inter-assay variations of the method averaged 7.3 and 12.2% of the man, respectively, when expressed as the coefficient of variation. Potency estimates of an insulin product obtained with the proposed method correlated well with those determined by the mouse convulsion bioassay method. Liver membranes prepared according to the method could be stored for up to ten weeks at 4/sup 0/C and for 6 months or more at -18/sup 0/C without losing insulin-binding ability.

  18. Inverse methods for radiation transport

    Bledsoe, Keith C.

    Implicit optimization methods for solving the inverse transport problems of interface location identification, source isotope weight fraction identification, shield material identification, and material mass density identification are explored. Among these optimization methods are the Schwinger inverse method, Levenberg-Marquardt method, and evolutionary algorithms. Inverse problems are studied in one-dimensional spherical and two-dimensional cylindrical geometries. The scalar fluxes of unscattered gamma-ray lines, leakages of neutron-induced gamma-ray lines, and/or neutron multiplication in the system are assumed to be measured. Each optimization method is studied on numerical test problems in which the measured data is simulated using the same deterministic transport code used in the optimization process (assuming perfectly consistent measurements) and using a Monte Carlo code (assuming less-consistent, more realistic measurements). The Schwinger inverse method and Levenberg-Marquardt methods are found to be successful for problems with relatively few (i.e. 4 or fewer) unknown parameters, with the former being the best for unknown isotope problems and the latter being more adept at interface location, unknown material mass density, and mixed parameter problems. A study of a variety of evolutionary algorithms indicates that the differential evolution method is the best for inverse transport problems, and outperforms the Levenberg-Marquardt method on problems with large numbers of unknowns. An algorithm created by combining different variants of the differential evolution method is shown to be highly successful on spherical problems with unscattered gamma-ray lines, while a basic differential evolution approach is more useful for problems with scattering and in cylindrical geometries. A hybrid differential evolution/Levenberg-Marquardt algorithm also was found to show promise for fast and robust solution of inverse problems.

  19. Enhancing the (MSLDIP) image steganographic method (ESLDIP method)

    Seddik Saad, Al-hussien


    Message transmissions over the Internet still have data security problem. Therefore, secure and secret communication methods are needed for transmitting messages over the Internet. Cryptography scrambles the message so that it cannot be understood. However, it makes the message suspicious enough to attract eavesdropper's attention. Steganography hides the secret message within other innocuous-looking cover files (i.e. images, music and video files) so that it cannot be observed [1].The term steganography originates from the Greek root words "steganos'' and "graphein'' which literally mean "covered writing''. It is defined as the science that involves communicating secret data in an appropriate multimedia carrier, e.g., image, audio text and video files [3].Steganographic techniques allow one party to communicate information to another without a third party even knowing that the communication is occurring. The ways to deliver these "secret messages" vary greatly [3].Our proposed method called Enhanced SLDIP (ESLDIP). In which the maximmum hiding capacity (MHC) of proposed ESLDIP method is higher than the previously proposed MSLDIP methods and the PSNR of the ESLDIP method is higher than the MSLDIP PSNR values', which means that the image quality of the ESLDIP method will be better than MSLDIP method and the maximmum hiding capacity (MHC) also improved. The rest of this paper is organized as follows. In section 2, steganography has been discussed; lingo, carriers and types. In section 3, related works are introduced. In section 4, the proposed method will be discussed in details. In section 5, the simulation results are given and Section 6 concludes the paper.

  20. A Natural Method for Family Planning: Lactational Amenorrhea Method

    Ayten Senturk Erenel


    Full Text Available Use of an family planning method during the postpartum period is important both to space births, and to prevent unwanted pregnancies. Under-utilization of family planning services during this period not only leads to adverse conditions caused by excessive fertility, but also has negative effects on both maternal and infant health. Women are in close contact with health care providers before, during, and after childbirth, when they are most likely to be impressed by the services they receive. Effective provision of health care services in these periods is therefore of great importance. Literature indicates high rates of success and compliance with family planning services provided during these periods. Many women neglect to use a modern contraceptive method in the postpartum period believing that breastfeeding alone ensures sufficient protection against pregnancy. Indeed, breastfeeding can be 98% effective as a contraceptive method; however, this is only true if certain criteria are observed. There are three basic criteria for the lactational amenorrhea method to be effective: the baby must be less than six months old, must be exclusively or almost exclusively breast-fed, and the mother must not be menstruating. In a conference held in Bellago in August 1988 by the World Health Organization and other international agencies, a consensus was developed for effective use of lactational amenorrhea method, and it was agreed to adopt breastfeeding as a potential family planning method in maternal and child health programs. [TAF Prev Med Bull 2010; 9(4.000: 383-390

  1. Statistical methods in language processing.

    Abney, Steven


    The term statistical methods here refers to a methodology that has been dominant in computational linguistics since about 1990. It is characterized by the use of stochastic models, substantial data sets, machine learning, and rigorous experimental evaluation. The shift to statistical methods in computational linguistics parallels a movement in artificial intelligence more broadly. Statistical methods have so thoroughly permeated computational linguistics that almost all work in the field draws on them in some way. There has, however, been little penetration of the methods into general linguistics. The methods themselves are largely borrowed from machine learning and information theory. We limit attention to that which has direct applicability to language processing, though the methods are quite general and have many nonlinguistic applications. Not every use of statistics in language processing falls under statistical methods as we use the term. Standard hypothesis testing and experimental design, for example, are not covered in this article. WIREs Cogni Sci 2011 2 315-322 DOI: 10.1002/wcs.111 For further resources related to this article, please visit the WIREs website.

  2. Piecewise-adaptive decomposition methods

    Ramos, J.I. [Room I-320-D, E.T.S. Ingenieros Industriales, Universidad de Malaga, Plaza El Ejido, s/n, 29013 Malaga (Spain)], E-mail:


    Piecewise-adaptive decomposition methods are developed for the solution of nonlinear ordinary differential equations. These methods are based on some theorems that show that Adomian's decomposition method is a homotopy perturbation technique and coincides with Taylor's series expansions for autonomous ordinary differential equations. Piecewise-decomposition methods provide series solutions in intervals which are subject to continuity conditions at the end points of each interval, and their adaption is based on the use of either a fixed number of approximants and a variable step size, a variable number of approximants and a fixed step size or a variable number of approximants and a variable step size. It is shown that the appearance of noise terms in the decomposition method is related to both the differential equation and the manner in which the homotopy parameter is introduced, especially for the Lane-Emden equation. It is also shown that, in order to avoid the use of numerical quadrature, there is a simple way of introducing the homotopy parameter in the two first-order ordinary differential equations that correspond to the second-order Thomas-Fermi equation. It is also shown that the piecewise homotopy perturbation methods presented here provide more accurate results than a modified Adomian decomposition technique which makes use of Pade approximants and the homotopy analysis method, for the Thomas-Fermi equation.

  3. Integral equation methods for electromagnetics

    Volakis, John


    This text/reference is a detailed look at the development and use of integral equation methods for electromagnetic analysis, specifically for antennas and radar scattering. Developers and practitioners will appreciate the broad-based approach to understanding and utilizing integral equation methods and the unique coverage of historical developments that led to the current state-of-the-art. In contrast to existing books, Integral Equation Methods for Electromagnetics lays the groundwork in the initial chapters so students and basic users can solve simple problems and work their way up to the mo

  4. A method of phenomenological interviewing.

    Bevan, Mark T


    In this article I propose a method of interviewing for descriptive phenomenological research that offers an explicit, theoretically based approach for researchers. My approach enables application of descriptive phenomenology as a total method for research, and not one just focused on data analysis. This structured phenomenological approach to interviewing applies questions based on themes of experience contextualization, apprehending the phenomenon and its clarification. The method of questioning employs descriptive and structural questioning as well as novel use of imaginative variation to explore experience. The approach will help researchers understand how to undertake descriptive phenomenological research interviews.

  5. Lectures on the coupling method

    Lindvall, Torgny


    An important tool in probability theory and its applications, the coupling method is primarily used in estimates of total variation distances. The method also works well in establishing inequalities, and it has proven highly successful in the study of Markov and renewal process asymptotics. This text represents a detailed, comprehensive examination of the method and its broad variety of applications. Readers progress from simple to advanced topics, with end-of-discussion notes that reinforce the preceding material. Topics include renewal theory, Markov chains, Poisson approximation, ergodicity

  6. Manufacturing method of photonic crystal

    Park, In Sung; Lee, Tae Ho; Ahn, Jin Ho; Biswas, Rana; Constant, Kristen P.; Ho, Kai-Ming; Lee, Jae-Hwang


    A manufacturing method of a photonic crystal is provided. In the method, a high-refractive-index material is conformally deposited on an exposed portion of a periodic template composed of a low-refractive-index material by an atomic layer deposition process so that a difference in refractive indices or dielectric constants between the template and adjacent air becomes greater, which makes it possible to form a three-dimensional photonic crystal having a superior photonic bandgap. Herein, the three-dimensional structure may be prepared by a layer-by-layer method.


    Ilya Levin


    Full Text Available DDoS attacks have become one of the most dangerous issues in the Internet today. Because of theseattacks, legitimate users can not access the resources they need. In [1] authors proposeda combined method for tracing and blocking the sources of DDoS-attacks. The essence of the method isthat each router marks the network packet that passes through it using a random hash function from theset. At the receiving side this information is stored and used to filter unwanted traffic and traceback thesource of distributed attack. This article describes the simulation and its results of the combined method.

  8. Statistical methods for physical science

    Stanford, John L


    This volume of Methods of Experimental Physics provides an extensive introduction to probability and statistics in many areas of the physical sciences, with an emphasis on the emerging area of spatial statistics. The scope of topics covered is wide-ranging-the text discusses a variety of the most commonly used classical methods and addresses newer methods that are applicable or potentially important. The chapter authors motivate readers with their insightful discussions, augmenting their material withKey Features* Examines basic probability, including coverage of standard distributions, time s

  9. Methods of statistical model estimation

    Hilbe, Joseph


    Methods of Statistical Model Estimation examines the most important and popular methods used to estimate parameters for statistical models and provide informative model summary statistics. Designed for R users, the book is also ideal for anyone wanting to better understand the algorithms used for statistical model fitting. The text presents algorithms for the estimation of a variety of regression procedures using maximum likelihood estimation, iteratively reweighted least squares regression, the EM algorithm, and MCMC sampling. Fully developed, working R code is constructed for each method. Th

  10. New methods of concurrent checking

    Goessel, Michael; Sogomonyan, Egor; Marienfeld, Daniel


    Written by a team of two leading experts and two very successful young former PhD students, New Methods of Concurrent Checking describes new methods of concurrent checking, such as partial duplication, use of output dependencies, complementary circuits, self-dual parity, self-dual duplication and others. A special chapter demonstrates how the new general methods of concurrent checking can be more specifically applied to regular structures to obtain optimum results. This is exemplified for all types of adders up to 64 bits with a level of detail never before presented in the literature. The cle

  11. Deconvolution Method for TOFD Technique

    Lee, Sun Heum; Kim, Sun Hyoung; Kong, Yong Hae [Soonchunhyang University, Asan (Korea, Republic of); Lee, Weon Heum [Acohlap, Bucheon (Korea, Republic of)


    Time of flight diffraction(TOFD) method is used in nondestructive tests of piping and pressure vessels because of its advantages over a pulse echo technique: its speed, objectivity, repeatability and its insensitivity to specimen surface conditions and discontinuity orientation. But it is the one of weak points in TOFD method that it has the dead zone in sub-surface resolution induced by lateral waves. We solved the dead-zone problem near the sub-surface by using the deconvolution method and the developed ultrasonic testing system showed high performance

  12. A Tutorial on Heuristic Methods

    Vidal, Rene Victor Valqui; Werra, D. de; Silver, E.


    In this paper we define a heuristic method as a procedure for solving a well-defined mathematical problem by an intuitive approach in which the structure of the problem can be interpreted and exploited intelligently to obtain a reasonable solution. Issues discussed include: (i) the measurement...... of the quality of a heuristic method, (ii) different types of heuristic procedures, (iii) the interactive role of human beings and (iv) factors that may influence the choice or testing of heuristic methods. A large number of references are included....

  13. User-centered agile method

    Deuff, Dominique


    Agile development methods began to emerge around 20 years ago. However, it was not until the early 2000s that they began to be widely used in industry. This growth was often due to the advent of Internet services requiring faster cycles of development in order to heighten the rate at which an ever-greater number of functionalities were made available. In parallel, user-centered design (UCD) methods were also becoming more and more widely used: hence, user-centered design and agile methods were bound to cross paths, at least in the telecoms industry! During this period, in the field of telec

  14. Ensemble Methods Foundations and Algorithms

    Zhou, Zhi-Hua


    An up-to-date, self-contained introduction to a state-of-the-art machine learning approach, Ensemble Methods: Foundations and Algorithms shows how these accurate methods are used in real-world tasks. It gives you the necessary groundwork to carry out further research in this evolving field. After presenting background and terminology, the book covers the main algorithms and theories, including Boosting, Bagging, Random Forest, averaging and voting schemes, the Stacking method, mixture of experts, and diversity measures. It also discusses multiclass extension, noise tolerance, error-ambiguity a

  15. Nonparametric statistical methods using R

    Kloke, John


    A Practical Guide to Implementing Nonparametric and Rank-Based ProceduresNonparametric Statistical Methods Using R covers traditional nonparametric methods and rank-based analyses, including estimation and inference for models ranging from simple location models to general linear and nonlinear models for uncorrelated and correlated responses. The authors emphasize applications and statistical computation. They illustrate the methods with many real and simulated data examples using R, including the packages Rfit and npsm.The book first gives an overview of the R language and basic statistical c

  16. Terrorism Financing Methods: An Overview

    Michael Freeman


    Full Text Available How do terrorists move money?  This article examines six of the most widely used methods: cash couriers, informal transfer systems (e.g. hawala, money service businesses, formal banking, false trade invoicing, and high value commodities.  When terrorists move money, they choose methods that take into account issues of: volume, risk, convenience, simplicity, costs, and speed. This article analyzes the methods according to these issues. It draws on multiple cases and examples, including the most recent cases of Hezbollah’s and al Shabaab’s use of money service businesses, and many others.

  17. Introduction to precise numerical methods

    Aberth, Oliver


    Precise numerical analysis may be defined as the study of computer methods for solving mathematical problems either exactly or to prescribed accuracy. This book explains how precise numerical analysis is constructed. The book also provides exercises which illustrate points from the text and references for the methods presented. All disc-based content for this title is now available on the Web. · Clearer, simpler descriptions and explanations ofthe various numerical methods· Two new types of numerical problems; accurately solving partial differential equations with the included software and computing line integrals in the complex plane.

  18. User-Centered Agile Methods

    Beyer, Hugh


    With the introduction and popularization of Agile methods of software development, existing relationships and working agreements between user experience groups and developers are being disrupted. Agile methods introduce new concepts: the Product Owner, the Customer (but not the user), short iterations, User Stories. Where do UX professionals fit in this new world? Agile methods also bring a new mindset -- no big design, no specifications, minimal planning -- which conflict with the needs of UX design. This lecture discusses the key elements of Agile for the UX community and describes strategie

  19. Probabilistic methods in combinatorial analysis

    Sachkov, Vladimir N


    This 1997 work explores the role of probabilistic methods for solving combinatorial problems. These methods not only provide the means of efficiently using such notions as characteristic and generating functions, the moment method and so on but also let us use the powerful technique of limit theorems. The basic objects under investigation are nonnegative matrices, partitions and mappings of finite sets, with special emphasis on permutations and graphs, and equivalence classes specified on sequences of finite length consisting of elements of partially ordered sets; these specify the probabilist

  20. Method of passivating semiconductor surfaces

    Wanlass, Mark W.


    A method of passivating Group III-V or II-VI semiconductor compound surfaces. The method includes selecting a passivating material having a lattice constant substantially mismatched to the lattice constant of the semiconductor compound. The passivating material is then grown as an ultrathin layer of passivating material on the surface of the Group III-V or II-VI semiconductor compound. The passivating material is grown to a thickness sufficient to maintain a coherent interface between the ultrathin passivating material and the semiconductor compound. In addition, a device formed from such method is also disclosed.

  1. Method of synthesizing tungsten nanoparticles

    Thoma, Steven G; Anderson, Travis M


    A method to synthesize tungsten nanoparticles has been developed that enables synthesis of nanometer-scale, monodisperse particles that can be stabilized only by tetrahydrofuran. The method can be used at room temperature, is scalable, and the product concentrated by standard means. Since no additives or stabilizing surfactants are required, this method is particularly well suited for producing tungsten nanoparticles for dispersion in polymers. If complete dispersion is achieved due to the size of the nanoparticles, then the optical properties of the polymer can be largely maintained.

  2. Machine learning methods for planning

    Minton, Steven


    Machine Learning Methods for Planning provides information pertinent to learning methods for planning and scheduling. This book covers a wide variety of learning methods and learning architectures, including analogical, case-based, decision-tree, explanation-based, and reinforcement learning.Organized into 15 chapters, this book begins with an overview of planning and scheduling and describes some representative learning systems that have been developed for these tasks. This text then describes a learning apprentice for calendar management. Other chapters consider the problem of temporal credi

  3. Bayesian Methods and Universal Darwinism

    Campbell, John


    Bayesian methods since the time of Laplace have been understood by their practitioners as closely aligned to the scientific method. Indeed a recent champion of Bayesian methods, E. T. Jaynes, titled his textbook on the subject Probability Theory: the Logic of Science. Many philosophers of science including Karl Popper and Donald Campbell have interpreted the evolution of Science as a Darwinian process consisting of a 'copy with selective retention' algorithm abstracted from Darwin's theory of Natural Selection. Arguments are presented for an isomorphism between Bayesian Methods and Darwinian processes. Universal Darwinism, as the term has been developed by Richard Dawkins, Daniel Dennett and Susan Blackmore, is the collection of scientific theories which explain the creation and evolution of their subject matter as due to the operation of Darwinian processes. These subject matters span the fields of atomic physics, chemistry, biology and the social sciences. The principle of Maximum Entropy states that system...

  4. Homogenization method for elastic materials

    Seifrt F.


    Full Text Available In the paper we study the homogenization method and its potential for research of some phenomenons connected with periodic elastic materials. This method will be applied on partial differential equations that describe the deformation of a periodic composite material. The next part of the paper will deal with applications of the homogenization method. The importance of the method will be discussed more detailed for the exploration of the so called bandgaps. Bandgap is a phenomenon which may appear during vibrations of some periodically heterogeneous materials. This phenomenon is not only observable during vibrations for the aforementioned materials, but we may also observe similar effects by propagation of electromagnetic waves of heterogeneous dielectric medias.

  5. Tree Formation Using Coordinate Method

    Monika Choudhary


    Full Text Available In this paper we are introducing a new method of tree formation, we propose a coordinate based method by which we can store and access tree structures. As we know in NLP, parsing is the most important module. The output of this module is generally parsed trees. Currently, TAG (Tree Adjoining Grammar is widely used grammar due to its linguistic and formal nature. It is simply tree generating system. The unit structure used in TAG is structured trees. So we used our new method to store trees where we worked on English to Hindi language. We worked on different sentences from English to Hindi, our method is the easiest way to manipulate tree. We have implemented within small corpus and for finite number of structures and further can be extended in future.

  6. Methods Courses and Student Teaching

    English, Donald E.


    Presents findings of a study conducted to determine the organization and characteristics of methods courses and student teaching in business education in the Mountain-Plains Region of the National Business Education Association. Recommendations are also provided. (TA)

  7. Semiclassical Methods in Chemical Physics.

    Miller, William H.


    Discusses the role of semiclassical theory in chemical physics both as a computational method and conceptual framework for interpreting quantum mechanical experiments and calculations. Topics covered include energy wells and eigenvalues, scattering, statistical mechanics and electronically nonadiabiatic processes. (JM)

  8. EPA Method 1682: Salmonella spp.

    Method 1682 describes procedures for analysis of solid samples (biosolids) and may be adapted for assessment of water, liquid, particulate and aerosol samples contaminated with Salmonella spp. using culture and immunoassay.

  9. A new vehicle detection method

    Zebbara Khalid


    Full Text Available This paper presents a new vehicle detection method from images acquired by cameras embedded in a moving vehicle. Given the sequence of images, the proposed algorithms should detect out all cars in realtime. Related to the driving direction, the cars can be classified into two types. Cars drive in the same direction as the intelligent vehicle (IV and cars drive in the opposite direction. Due to the distinct features of these two types, we suggest to achieve this method in two main steps. The first one detects all obstacles from images using the so-called association combined with corner detector. The second step is applied to validate each vehicle using AdaBoost classifier. The new method has been applied to different images data and the experimental results validate the efficacy of our method.

  10. Methods for treating lignocellulosic materials

    Jansen, Robert; Gregoire, Claire; Travisano, Philip; Madsen, Lee; Matis, Neta; Har-Tal, Yael; Eliahu, Shay; Lawson, James Alan; Lapidot, Noa; Eyal, Aharon M.; Bauer, Timothy Allen; Sade, Hagit; McWilliams, Paul; Zviely, Michael; Carden, Adam


    The present invention relates to methods of processing lignocellulosic material to obtain hemicellulose sugars, cellulose sugars, lignin, cellulose and other high-value products. Also provided are hemicellulose sugars, cellulose sugars, lignin, cellulose, and other high-value products.

  11. Graph modeling systems and methods

    Neergaard, Mike


    An apparatus and a method for vulnerability and reliability modeling are provided. The method generally includes constructing a graph model of a physical network using a computer, the graph model including a plurality of terminating vertices to represent nodes in the physical network, a plurality of edges to represent transmission paths in the physical network, and a non-terminating vertex to represent a non-nodal vulnerability along a transmission path in the physical network. The method additionally includes evaluating the vulnerability and reliability of the physical network using the constructed graph model, wherein the vulnerability and reliability evaluation includes a determination of whether each terminating and non-terminating vertex represents a critical point of failure. The method can be utilized to evaluate wide variety of networks, including power grid infrastructures, communication network topologies, and fluid distribution systems.

  12. Legal method in danish law

    Blume, Peter Erik

    This book describes how legal method is used within the Danish legal system. Its target group is foreign lawyers and law students who have an interest in knowing how Danish law commonly is determined and applied. In the first chapters legal method and legal sources in general are defined and furt......This book describes how legal method is used within the Danish legal system. Its target group is foreign lawyers and law students who have an interest in knowing how Danish law commonly is determined and applied. In the first chapters legal method and legal sources in general are defined...... and furthermore a brief account of Danish legal history is provided. The following chapters concern: • Legal institutions, • Statute and Statutory Law • Legal Decisions • Legal Literature and Legal Knowledge • Other National Legal Sources • External Influences on Danish Law...

  13. Methods for Analyzing Pipe Networks

    Nielsen, Hans Bruun


    The governing equations for a general network are first set up and then reformulated in terms of matrices. This is developed to show that the choice of model for the flow equations is essential for the behavior of the iterative method used to solve the problem. It is shown that it is better...... to formulate the flow equations in terms of pipe discharges than in terms of energy heads. The behavior of some iterative methods is compared in the initial phase with large errors. It is explained why the linear theory method oscillates when the iteration gets close to the solution, and it is further...... demonstrated that this method offers good starting values for a Newton-Raphson iteration....

  14. Method for controlling powertrain pumps

    Sime, Karl Andrew; Spohn, Brian L; Demirovic, Besim; Martini, Ryan D; Miller, Jean Marie


    A method of controlling a pump supplying a fluid to a transmission includes sensing a requested power and an excess power for a powertrain. The requested power substantially meets the needs of the powertrain, while the excess power is not part of the requested power. The method includes sensing a triggering condition in response to the ability to convert the excess power into heat in the transmission, and determining that an operating temperature of the transmission is below a maximum. The method also includes determining a calibrated baseline and a dissipation command for the pump. The calibrated baseline command is configured to supply the fluid based upon the requested power, and the dissipation command is configured to supply additional fluid and consume the excess power with the pump. The method operates the pump at a combined command, which is equal to the calibrated baseline command plus the dissipation command.

  15. Functional methods in differential equations

    Hokkanen, Veli-Matti


    In recent years, functional methods have become central to the study of theoretical and applied mathematical problems. As demonstrated in this Research Note, functional methods can not only provide more generality, but they can also unify results and techniques and lead to better results than those obtained by classical methods. Presenting entirely original results, the authors use functional methods to explore a broad range of elliptic, parabolic, and hyperbolic boundary value problems and various classes of abstract differential and integral equations. They show that while it is crucial to choose an appropriate functional framework, this approach can lead to mathematical models that better describe concrete physical phenomena. In particular, they reach a concordance between the physical sense and the mathematical sense for the solutions of some special models. Beyond its importance as a survey of the primary techniques used in the area, the results illuminated in this volume will prove valuable in a wealth ...

  16. Propagating Class and Method Combination

    Ernst, Erik


    This paper presents a mixin based class and method combination mechanism with block structure propagation. Traditionally, mixins can be composed to form new classes, possibly merging the implementations of methods (as in CLOS). In our approach, a class or method combination operation may cause any...... number of implicit combinations. For example, it is possible to specify separate aspects of a family of classes, and then combine several aspects into a full-fledged class family. The combination expressions would explicitly combine whole-family aspects, and by propagation implicitly combine the aspects...... for each member of the class family, and again by propagation implicitly compose each method from its aspects. As opposed to CLOS, this is type-checked statically; and as opposed to other systems for advanced class combination/ merging/weaving, it is integrated directly in the language, ensuring a clear...

  17. Tourism research and audio methods

    Jensen, Martin Trandberg


    • Audio methods enriches sensuous tourism ethnographies. • The note suggests five research avenues for future auditory scholarship. • Sensuous tourism research has neglected the role of sounds in embodied tourism experiences.......• Audio methods enriches sensuous tourism ethnographies. • The note suggests five research avenues for future auditory scholarship. • Sensuous tourism research has neglected the role of sounds in embodied tourism experiences....

  18. The Gravisphere Method Algorithm Programming

    Rosaev, A. E.


    The action sphere method program is written. The initial conditions set at pericenter of planetocentric orbits. When action sphere radius is reached, the heliocentric orbit is calculated and data redirected to numeric integration program. The method is useful for capture and collision problem investigation. The very preliminary numeric results were obtained and discussed. A manifold in orbital elements space, leads to temporary capture about 50 year (4 Jupiter revolutions), was found.

  19. New methods for creating superoscillations

    Chojnacki, Leilee; Kempf, Achim


    Superoscillating functions, i.e. functions that locally oscillate at a rate faster than their highest Fourier component, are of interest for applications from fundamental physics to engineering. Here, we develop a new method which allows one to construct superoscillations of arbitrarily high frequency and arbitrarily long duration in a computationally efficient way. We also present a method for constructing non-singular Schrödinger potentials whose ground state is a superoscillating wave function.

  20. Novel methods for tendon investigations

    Kjaer, M; Langberg, H; Bojsen-Møller, J;


    PURPOSE: Tendon structures have been studied for decades, but over the last decade, methodological development and renewed interest for metabolic, circulatory and tissue protein turnover in tendon tissue has resulted in a rising amount of investigations. METHOD: This paper will detail the various...... modern investigative techniques available to study tendons. RESULTS: There are a variety of investigative methods available to study the correlations between mechanics and biology in tendons. CONCLUSION: The available methodologies not only allow for potential insight into physiological...

  1. System and method for authentication

    Duerksen, Gary L.; Miller, Seth A.


    Described are methods and systems for determining authenticity. For example, the method may include providing an object of authentication, capturing characteristic data from the object of authentication, deriving authentication data from the characteristic data of the object of authentication, and comparing the authentication data with an electronic database comprising reference authentication data to provide an authenticity score for the object of authentication. The reference authentication data may correspond to one or more reference objects of authentication other than the object of authentication.

  2. New disinfection and sterilization methods.


    New disinfection methods include a persistent antimicrobial coating that can be applied to inanimate and animate objects (Surfacine), a high-level disinfectant with reduced exposure time (ortho-phthalaldehyde), and an antimicrobial agent that can be applied to animate and inanimate objects (superoxidized water). New sterilization methods include a chemical sterilization process for endoscopes that integrates cleaning (Endoclens), a rapid (4-hour) readout biological indicator for ethylene oxid...

  3. Analytic Methods for Cosmological Likelihoods

    Taylor, A. N.; Kitching, T. D.


    We present general, analytic methods for Cosmological likelihood analysis and solve the "many-parameters" problem in Cosmology. Maxima are found by Newton's Method, while marginalization over nuisance parameters, and parameter errors and covariances are estimated by analytic marginalization of an arbitrary likelihood function with flat or Gaussian priors. We show that information about remaining parameters is preserved by marginalization. Marginalizing over all parameters, we find an analytic...

  4. [Isaac Newton's Anguli Contactus method].

    Wawrzycki, Jarosław


    In this paper we discuss the geometrical method for calculating the curvature of a class of curves from the third Book of Isaac Newton's Principia. The method involves any curve which is generated from an elementary curve (actually from any curve whose curvature we known of) by means of transformation increasing the polar angular coordinate in a constant ratio, but unchanging the polar radial angular coordinate.

  5. Euler/Navier-Stokes Methods

    Pulliam, Tom; Kwak, Dochan (Technical Monitor)


    Implicit methods have been the workhorse for the Euler and Navier-Stokes equations for the last 25 years. The ground breaking work of Dr. Joe Steger in implementing such techniques in practical Euler and Navier-Stokes codes provided the basis for all the success in this area. This presentation will highlight his contribution and technical excellence in the area of implicit methods for CFD.

  6. A nonperturbative method for QCD

    Jora, Renata


    Based on specific properties of the partition function and of the quantum correlators we derive the exact form of the beta function in the background gauge field method for QCD with an arbitrary number of flavors. The all order beta function we obtain through this method has only the first two orders coefficients different than zero and thus is equivalent to the 't Hooft scheme.

  7. Information System Quality Assessment Methods


    This thesis explores challenging topic of information system quality assessment and mainly process assessment. In this work the term Information System Quality is defined as well as different approaches in a quality definition for different domains of information systems are outlined. Main methods of process assessment are overviewed and their relationships are described. Process assessment methods are divided into two categories: ISO standards and best practices. The main objective of this w...

  8. Combinatorial methods with computer applications

    Gross, Jonathan L


    Combinatorial Methods with Computer Applications provides in-depth coverage of recurrences, generating functions, partitions, and permutations, along with some of the most interesting graph and network topics, design constructions, and finite geometries. Requiring only a foundation in discrete mathematics, it can serve as the textbook in a combinatorial methods course or in a combined graph theory and combinatorics course.After an introduction to combinatorics, the book explores six systematic approaches within a comprehensive framework: sequences, solving recurrences, evaluating summation exp

  9. Critical review on biofilm methods

    Azeredo, Joana; F. Azevedo, Nuno; Briandet, Romain


    Biofilms are widespread in nature and constitute an important strategy implemented by microorganisms to survive in sometimes harsh environmental conditions. They can be beneficial or have a negative impact particularly when formed in industrial settings or on medical devices. As such, research in...... and limitations of several methods. Accordingly, this review aims at helping scientists in finding the most appropriate and up-to-date methods to study their biofilms....

  10. Efficient methods of piping cleaning

    Orlov Vladimir Aleksandrovich; Nechitaeva Valentina Anatol'evna; Bogomolova Irina Olegovna; Shaykhetdinova Yuliya Aleksandrovna; Daminova Yuliya Farikhovna


    The article contains the analysis of the efficient methods of piping cleaning of water supply and sanitation systems. Special attention is paid to the ice cleaning method, in course of which biological foil and various mineral and organic deposits are removed due to the ice crust buildup on the inner surface of water supply and drainage pipes. These impurities are responsible for the deterioration of the organoleptic properties of the transported drinking water or narrowing cross-section of d...

  11. Decomposition methods in turbulence research

    Uruba Václav


    Full Text Available Nowadays we have the dynamical velocity vector field of turbulent flow at our disposal coming thanks advances of either mathematical simulation (DNS or of experiment (time-resolved PIV. Unfortunately there is no standard method for analysis of such data describing complicated extended dynamical systems, which is characterized by excessive number of degrees of freedom. An overview of candidate methods convenient to spatiotemporal analysis for such systems is to be presented. Special attention will be paid to energetic methods including Proper Orthogonal Decomposition (POD in regular and snapshot variants as well as the Bi-Orthogonal Decomposition (BOD for joint space-time analysis. Then, stability analysis using Principal Oscillation Patterns (POPs will be introduced. Finally, the Independent Component Analysis (ICA method will be proposed for detection of coherent structures in turbulent flow-field defined by time-dependent velocity vector field. Principle and some practical aspects of the methods are to be shown. Special attention is to be paid to physical interpretation of outputs of the methods listed above.




    Full Text Available Audit sampling involves the application of audit procedures to less than 100% of items within an account balance or class of transactions. Our article aims to study audit sampling in audit of financial statements. As an audit technique largely used, in both its statistical and nonstatistical form, the method is very important for auditors. It should be applied correctly for a fair view of financial statements, to satisfy the needs of all financial users. In order to be applied correctly the method must be understood by all its users and mainly by auditors. Otherwise the risk of not applying it correctly would cause loose of reputation and discredit, litigations and even prison. Since there is not a unitary practice and methodology for applying the technique, the risk of incorrectly applying it is pretty high. The SWOT analysis is a technique used that shows the advantages, disadvantages, threats and opportunities. We applied SWOT analysis in studying the sampling method, from the perspective of three players: the audit company, the audited entity and users of financial statements. The study shows that by applying the sampling method the audit company and the audited entity both save time, effort and money. The disadvantages of the method are difficulty in applying and understanding its insight. Being largely used as an audit method and being a factor of a correct audit opinion, the sampling method’s advantages, disadvantages, threats and opportunities must be understood by auditors.

  13. Manifold methods for methane combustion

    Yang, B.; Pope, S.B. [Cornell Univ., Ithaca, NY (United States)


    Great progresses have been made in combustion research, especially, the computation of laminar flames and the probability density function (PDF) method in turbulent combustion. For one-dimensional laminar flames, by considering the transport mechanism, the detailed chemical kinetic mechanism and the interactions between these two basic processes, today it is a routine matter to calculate flame velocities, extinction, ignition, temperature, and species distributions from the governing equations. Results are in good agreement with those obtained for experiments. However, for turbulent combustion, because of the complexities of turbulent flow, chemical reactions, and the interaction between them, in the foreseeable future, it is impossible to calculate the combustion flow field by directly integrating the basic governing equations. So averaging and modeling are necessary in turbulent combustion studies. Averaging, on one hand, simplifies turbulent combustion calculations, on the other hand, it introduces the infamous closure problems, especially the closure problem with chemical reaction terms. Since in PDF calculations of turbulent combustion, the averages of the chemical reaction terms can be calculated, PDF methods overcome the closure problem with the reaction terms. It has been shown that the PDF method is a most promising method to calculate turbulent combustion. PDF methods have been successfully employed to calculate laboratory turbulent flames: they can predict phenomena such as super equilibrium radical levels, and local extinction. Because of these advantages, PDF methods are becoming used increasingly in industry combustor codes.

  14. New numerical analysis method in computational mechanics: composite element method


    A new type of FEM, called CEM (composite element method), is proposed to solve the static and dynamic problems of engineering structures with high accuracy and efficiency. The core of this method is to define two sets of coordinate systems for DOF's description after discretizing the structure, i.e. the nodal coordinate system UFEM(ξ) for employing the conventional FEM, and the field coordinate system UCT(ξ) for utilizing classical theory. Then, coupling these two sets of functional expressions could obtain the composite displacement field U(ξ) of CEM. The computations of the stiffness and mass matrices can follow the conventional procedure of FEM. Since the CEM inherents some good properties of the conventional FEM and classical analytical method, it has the powerful versatility to various complex geometric shapes and excellent approximation. Many examples are presented to demonstrate the ability of CEM.

  15. New numerical analysis method in computational mechanics: composite element method



    A new type of FEM, called CEM (composite element method), is proposed to solve the static and dynamic problems of engineering structures with high accuracy and efficiency. The core of this method is to define two sets of coordinate systems for DOF’ s description after discretizing the structure, i.e. the nodal coordinate system UFEM(ζ) for employing the conventional FEM, and the field coordinate system UCT(ζ) for utilizing classical theory. Then, coupling these two sets of functional expressions could obtain the composite displacement field U(ζ) of CEM. The computations of the stiffness and mass matrices can follow the conventional procedure of FEM. Since the CEM inherents some good properties of the conventional FEM and classical analytical method, it has the powerful versatility to various complex geometric shapes and excellent approximation. Many examples are presented to demonstrate the ability of CEM.

  16. Adaptive Integral Method for Higher Order Method of Moments

    Kim, Oleksiy S.; Meincke, Peter


    The adaptive integral method (AIM) is combined with the higher order method of moments (MoM) to solve integral equations. The technique takes advantage of the low computational complexity and memory requirements of the AIM and the reduced number of unknowns and higher order convergence of higher...... order basis functions. The classical AIM is appropriately modified to allow larger discretization elements and, consequently, higher basis function expansion orders. Numerical examples based on the higher order hierarchical Legendre basis functions show the advantages of the proposed technique over...... the classical AIM based on low-order basis functions in terms of memory and computational time....

  17. Improved Method for Lacosamide Synthesis with Chemoenzymatic Method

    WANG Zhi-yuan; XU Li-sheng; LIU Jun-zhong; ZHANG Hong-juan; GAO Ji; LIU Qian; JIAO Qing-cai


    Lacosamide was prepared by chemical method coupled with enzymatic method.N-Acetyl-D,L-3-methoxy-alanine,derived from D,L-3-methoxy-alanine,was used in the resolution process catalyzed by immobilized Escherichia coli cells with aminoacylase(EC3.5.1.14) activity.N-Acetyl-D-3-methoxy-alanine and L-3-methoxy-alanine were obtained from the resolution system.Lacosamide was synthesized by the amidation of N-acetyl-D-3-methoxy-alanine with benzylamine.

  18. A new method for orbit determination: Unit vector method


    In this paper, a method of orbit determination is presented according to the principle of unit vector method (UVM). The model and arithmetic are improved and it not only suits initial orbit determination with short arc data, it also suits orbit improvement with data longer. It is also suitable for orbit of any eccentricity and any inclination. It omits most partial derivatives of all the elements which must be calculated in classical differential orbit improvement (DOI), so, it is more efficient than DOI, and the accuracy of orbit determination and convergence of algorithm are also improved appreciably.

  19. Compressor instability with integral methods

    Ng, Y.K. Eddie [Nanyang Technological Univ., Singapore (Singapore). School of Mechanical and Aerospace Engineering; Liu, Ningyu [Singapore National Univ. (Singapore). Dept. of Mechanical Engineering


    ''Compressor Instability with Integral Methods'' is a book, to bring together the quick integral approaches and advances in the field for the prediction of stall and surge problem in compressor. This book is useful for people involved in the flow analysis, design and testing of rotating machinery. For students, it can be used as a specialized topic of senior undergraduate or graduate study. The book can also be served as a self-study material to those who keen to acquire this knowledge. In brief, this book focuses on the numerical/computational analysis for the effect of distorted inlet flow propagation on the rotating stall and surge in axial compressors. It gains insight into the basic phenomena controlling these flow instabilities, and reveals the influence of inlet parameters on rotating stall and surge. The book starts from the confirmation and application of Kim et al's integral method and then follows by a development to this method through the proposing and applying a critical distortion line. This line is applied successfully on the stall prediction of in-flight compressor due to flaming of refueling leakage near inlet, a typical real and interesting example of compressor stall and surge operation. Further, after a parametric study on the integral method and the distorted flow field of compressor using Taguchi method, a novel integral method is formulated using more appropriate and practical airfoil characteristics, with a less assumptions needed for derivation. Finally, as an extended work, the famous Greitzer's instability flow model, the well-known B-parameter model applied for analyzing the stall and surge characteristics, is studied parametrically using Taguchi method. (orig.)

  20. Methods for Melting Temperature Calculation

    Hong, Qi-Jun

    Melting temperature calculation has important applications in the theoretical study of phase diagrams and computational materials screenings. In this thesis, we present two new methods, i.e., the improved Widom's particle insertion method and the small-cell coexistence method, which we developed in order to capture melting temperatures both accurately and quickly. We propose a scheme that drastically improves the efficiency of Widom's particle insertion method by efficiently sampling cavities while calculating the integrals providing the chemical potentials of a physical system. This idea enables us to calculate chemical potentials of liquids directly from first-principles without the help of any reference system, which is necessary in the commonly used thermodynamic integration method. As an example, we apply our scheme, combined with the density functional formalism, to the calculation of the chemical potential of liquid copper. The calculated chemical potential is further used to locate the melting temperature. The calculated results closely agree with experiments. We propose the small-cell coexistence method based on the statistical analysis of small-size coexistence MD simulations. It eliminates the risk of a metastable superheated solid in the fast-heating method, while also significantly reducing the computer cost relative to the traditional large-scale coexistence method. Using empirical potentials, we validate the method and systematically study the finite-size effect on the calculated melting points. The method converges to the exact result in the limit of a large system size. An accuracy within 100 K in melting temperature is usually achieved when the simulation contains more than 100 atoms. DFT examples of Tantalum, high-pressure Sodium, and ionic material NaCl are shown to demonstrate the accuracy and flexibility of the method in its practical applications. The method serves as a promising approach for large-scale automated material screening in which

  1. Efficient methods of piping cleaning

    Orlov Vladimir Aleksandrovich


    Full Text Available The article contains the analysis of the efficient methods of piping cleaning of water supply and sanitation systems. Special attention is paid to the ice cleaning method, in course of which biological foil and various mineral and organic deposits are removed due to the ice crust buildup on the inner surface of water supply and drainage pipes. These impurities are responsible for the deterioration of the organoleptic properties of the transported drinking water or narrowing cross-section of drainage pipes. The co-authors emphasize that the use of ice compared to other methods of pipe cleaning has a number of advantages due to the relative simplicity and cheapness of the process, economical efficiency and lack of environmental risk. The equipment for performing ice cleaning is presented, its technological options, terms of cleansing operations, as well as the volumes of disposed pollution per unit length of the water supply and drainage pipelines. It is noted that ice cleaning requires careful planning in the process of cooking ice and in the process of its supply in the pipe. There are specific requirements to its quality. In particular, when you clean drinking water system the ice applied should be hygienically clean and meet sanitary requirements.In pilot projects, in particular, quantitative and qualitative analysis of sediments adsorbed by ice is conducted, as well as temperature and the duration of the process. The degree of pollution of the pipeline was estimated by the volume of the remote sediment on 1 km of pipeline. Cleaning pipelines using ice can be considered one of the methods of trenchless technologies, being a significant alternative to traditional methods of cleaning the pipes. The method can be applied in urban pipeline systems of drinking water supply for the diameters of 100—600 mm, and also to diversion collectors. In the world today 450 km of pipelines are subject to ice cleaning method.Ice cleaning method is simple

  2. Qualitative research as methodical hermeneutics.

    Rennie, David L


    The proportion of publications of qualitative research in mainstream psychology journals is small. Thus, in terms of this important criterion, despite its recent rapid growth, qualitative research is marginalized in psychology. The author suggests that contributing to this situation is the lack of a coherent and unifying methodology of qualitative research methods that elucidates their credibility. He groups the many qualitative research methods into 3 main kinds, then applies to them 4 propositions offered as such a methodology: (1) Qualitative research is hermeneutical, entailing application of the method of the hermeneutic circle to text about experience and/or action. (2) Implicit in the use of the hermeneutic circle method is the activity of educing and articulating the meaning of text, an activity that modifies and interacts with C. S. Peirce's (1965, 1966) logical operations of abduction, theorematic deduction, and induction. (3) The cycling of these 4 moments enables demonstration, achieved rhetorically, of the validity of the understandings resulting from the exegesis of the text under study. (4) This demonstrative rhetoric is enhanced when researchers disclose reflexively those aspects of their perspectives they judge to have most relevant bearing on their understandings. The author compares abduction as formulated here with other recent uptakes of it. As an installment on the generality of the methodology, he explores its fit with the descriptive phenomenological psychological method, conversation analysis, and thematic analysis.


    N. V. Merzlikin


    Full Text Available The methods of choledocholithiasis treatment, which are currently used in clinics of the Russian Federa-tion, has been presented. The problems of diagnosis and treatment of gallstones (GSD in individuals of different age groups are spotlighted. In the study of treatment of cholelithiasis and choledocholithiasis, including arising complications, it can be concluded that so far the ideal method of treatment of this pa-thology has not been found. Up to now, the majority of doctor’s main treatment is surgical removal of gall stones by some method or other.This article also considers a conservative approach (drug: antispasmodics (selective and nonselective, and non-pharmacological: treatment, diet, describes the criteria and assessment of the effectiveness of therapeutic interventions that help in the question of further treatment: the continuation of drug therapy or assignment of surgical treatment. Invasive techniques that are covered in the article, namely, a tech-nique of remote and endoscopic lithotripsy, are high-tech and in demand at the moment, which, along with high efficiency removal of a stone, reduced the number and severity of postoperative complications. Additionally, in the analysis of the features of a particular method of treatment, advantages and disadvantages of different treatment methods are described, indications and contraindications (absolute and relative together with complications, possible outcomes, and further prognosis are high-lighted. 

  4. Stochastic Methods for Aircraft Design

    Pelz, Richard B.; Ogot, Madara


    The global stochastic optimization method, simulated annealing (SA), was adapted and applied to various problems in aircraft design. The research was aimed at overcoming the problem of finding an optimal design in a space with multiple minima and roughness ubiquitous to numerically generated nonlinear objective functions. SA was modified to reduce the number of objective function evaluations for an optimal design, historically the main criticism of stochastic methods. SA was applied to many CFD/MDO problems including: low sonic-boom bodies, minimum drag on supersonic fore-bodies, minimum drag on supersonic aeroelastic fore-bodies, minimum drag on HSCT aeroelastic wings, FLOPS preliminary design code, another preliminary aircraft design study with vortex lattice aerodynamics, HSR complete aircraft aerodynamics. In every case, SA provided a simple, robust and reliable optimization method which found optimal designs in order 100 objective function evaluations. Perhaps most importantly, from this academic/industrial project, technology has been successfully transferred; this method is the method of choice for optimization problems at Northrop Grumman.

  5. Method for dense packing discovery.

    Kallus, Yoav; Elser, Veit; Gravel, Simon


    The problem of packing a system of particles as densely as possible is foundational in the field of discrete geometry and is a powerful model in the material and biological sciences. As packing problems retreat from the reach of solution by analytic constructions, the importance of an efficient numerical method for conducting de novo (from-scratch) searches for dense packings becomes crucial. In this paper, we use the divide and concur framework to develop a general search method for the solution of periodic constraint problems, and we apply it to the discovery of dense periodic packings. An important feature of the method is the integration of the unit-cell parameters with the other packing variables in the definition of the configuration space. The method we present led to previously reported improvements in the densest-known tetrahedron packing. Here, we use the method to reproduce the densest-known lattice sphere packings and the best-known lattice kissing arrangements in up to 14 and 11 dimensions, respectively, providing numerical evidence for their optimality. For nonspherical particles, we report a dense packing of regular four-dimensional simplices with density ϕ=128/219≈0.5845 and with a similar structure to the densest-known tetrahedron packing.

  6. Methods Data Qualification Interim Report

    R. Sam Alessi; Tami Grimmett; Leng Vang; Dave McGrath


    The overall goal of the Next Generation Nuclear Plant (NGNP) Data Management and Analysis System (NDMAS) is to maintain data provenance for all NGNP data including the Methods component of NGNP data. Multiple means are available to access data stored in NDMAS. A web portal environment allows users to access data, view the results of qualification tests and view graphs and charts of various attributes of the data. NDMAS also has methods for the management of the data output from VHTR simulation models and data generated from experiments designed to verify and validate the simulation codes. These simulation models represent the outcome of mathematical representation of VHTR components and systems. The methods data management approaches described herein will handle data that arise from experiment, simulation, and external sources for the main purpose of facilitating parameter estimation and model verification and validation (V&V). A model integration environment entitled ModelCenter is used to automate the storing of data from simulation model runs to the NDMAS repository. This approach does not adversely change the why computational scientists conduct their work. The method is to be used mainly to store the results of model runs that need to be preserved for auditing purposes or for display to the NDMAS web portal. This interim report demonstrates the currently development of NDMAS for Methods data and discusses data and its qualification that is currently part of NDMAS.

  7. Distance sampling methods and applications

    Buckland, S T; Marques, T A; Oedekoven, C S


    In this book, the authors cover the basic methods and advances within distance sampling that are most valuable to practitioners and in ecology more broadly. This is the fourth book dedicated to distance sampling. In the decade since the last book published, there have been a number of new developments. The intervening years have also shown which advances are of most use. This self-contained book covers topics from the previous publications, while also including recent developments in method, software and application. Distance sampling refers to a suite of methods, including line and point transect sampling, in which animal density or abundance is estimated from a sample of distances to detected individuals. The book illustrates these methods through case studies; data sets and computer code are supplied to readers through the book’s accompanying website.  Some of the case studies use the software Distance, while others use R code. The book is in three parts.  The first part addresses basic methods, the ...

  8. Kernel current source density method.

    Potworowski, Jan; Jakuczun, Wit; Lȩski, Szymon; Wójcik, Daniel


    Local field potentials (LFP), the low-frequency part of extracellular electrical recordings, are a measure of the neural activity reflecting dendritic processing of synaptic inputs to neuronal populations. To localize synaptic dynamics, it is convenient, whenever possible, to estimate the density of transmembrane current sources (CSD) generating the LFP. In this work, we propose a new framework, the kernel current source density method (kCSD), for nonparametric estimation of CSD from LFP recorded from arbitrarily distributed electrodes using kernel methods. We test specific implementations of this framework on model data measured with one-, two-, and three-dimensional multielectrode setups. We compare these methods with the traditional approach through numerical approximation of the Laplacian and with the recently developed inverse current source density methods (iCSD). We show that iCSD is a special case of kCSD. The proposed method opens up new experimental possibilities for CSD analysis from existing or new recordings on arbitrarily distributed electrodes (not necessarily on a grid), which can be obtained in extracellular recordings of single unit activity with multiple electrodes.

  9. Beyond Statistical Methods – Compendium of Statistical Methods for Researchers

    Ondřej Vozár


    Full Text Available Book Review: HENDL, J. Přehled statistických metod: Analýza a metaanalýza dat (Overview of Statistical Methods: Data Analysis and Metaanalysis. 4th extended edition. Prague: Portál, 2012. ISBN 978-80-262-0200-4.

  10. Scalable fast multipole methods for vortex element methods

    Hu, Qi


    We use a particle-based method to simulate incompressible flows, where the Fast Multipole Method (FMM) is used to accelerate the calculation of particle interactions. The most time-consuming kernelsâ\\'the Biot-Savart equation and stretching term of the vorticity equationâ\\'are mathematically reformulated so that only two Laplace scalar potentials are used instead of six, while automatically ensuring divergence-free far-field computation. Based on this formulation, and on our previous work for a scalar heterogeneous FMM algorithm, we develop a new FMM-based vortex method capable of simulating general flows including turbulence on heterogeneous architectures, which distributes the work between multi-core CPUs and GPUs to best utilize the hardware resources and achieve excellent scalability. The algorithm also uses new data structures which can dynamically manage inter-node communication and load balance efficiently but with only a small parallel construction overhead. This algorithm can scale to large-sized clusters showing both strong and weak scalability. Careful error and timing trade-off analysis are also performed for the cutoff functions induced by the vortex particle method. Our implementation can perform one time step of the velocity+stretching for one billion particles on 32 nodes in 55.9 seconds, which yields 49.12 Tflop/s. © 2012 IEEE.

  11. The Objective Borderline Method: A Probabilistic Method for Standard Setting

    Shulruf, Boaz; Poole, Phillippa; Jones, Philip; Wilkinson, Tim


    A new probability-based standard setting technique, the Objective Borderline Method (OBM), was introduced recently. This was based on a mathematical model of how test scores relate to student ability. The present study refined the model and tested it using 2500 simulated data-sets. The OBM was feasible to use. On average, the OBM performed well…

  12. Combining building thermal simulation methods and LCA methods

    Pedersen, Frank; Hansen, Klaus; Wittchen, Kim Bjarne


    Thsi paper describes recent efforts made by the Danish Building Research Institute regarding the integration of a life cycle assessment (LCA) method into a whole building hygro-thermal simulation tool. The motivation for the work is that the increased requirements to the energy performance...


    Jun Liu


    Full Text Available Do methods still have a place in 21" century language teaching? To answer this question, an international survey was conducted in the surnmer of 1999. A sample of 800 language teachers world-wide randomly drawn from 17,800 TESOLers were each given a 2-page survey. The return rate was 58.5% with the actual usable data set of448, which was analyzed by using both descriptive and inferential statistics. Among the ten commonly recognized teaching methods surveyed, both the Communicative Language Teaching Approach and an eclectic method seem to have the highest rate in familiarity, preference, and use. But when multiple factors, such as teaching contexts, instructional settings, learners' proficiency levels, class size, teaching experience and educational backgrounds of the teachers, and the status of being a native or nonnative English speaking professional were taken into consideration, various patterns and themes emerged. One interesting finding is that Grammar Translation is still used in EFL contexts, in larger classes, and with learners at low proficiency levels, though the ratio between the actual use of this method and teachers' preference does not match. Based on the results of the survey, a new theoretical framework is proposed to conceptualize language teaching methods in the post-methods era.

  14. Methods of producing transportation fuel

    Nair, Vijay; Roes, Augustinus Wilhelmus Maria; Cherrillo, Ralph Anthony; Bauldreay, Joanna M.


    Systems, methods, and heaters for treating a subsurface formation are described herein. At least one method for producing transportation fuel is described herein. The method for producing transportation fuel may include providing formation fluid having a boiling range distribution between C. and C. from a subsurface in situ heat treatment process to a subsurface treatment facility. A liquid stream may be separated from the formation fluid. The separated liquid stream may be hydrotreated and then distilled to produce a distilled stream having a boiling range distribution between C. and C. The distilled liquid stream may be combined with one or more additives to produce transportation fuel.

  15. Critical review on biofilm methods.

    Azeredo, Joana; Azevedo, Nuno F; Briandet, Romain; Cerca, Nuno; Coenye, Tom; Costa, Ana Rita; Desvaux, Mickaël; Di Bonaventura, Giovanni; Hébraud, Michel; Jaglic, Zoran; Kačániová, Miroslava; Knøchel, Susanne; Lourenço, Anália; Mergulhão, Filipe; Meyer, Rikke Louise; Nychas, George; Simões, Manuel; Tresse, Odile; Sternberg, Claus


    Biofilms are widespread in nature and constitute an important strategy implemented by microorganisms to survive in sometimes harsh environmental conditions. They can be beneficial or have a negative impact particularly when formed in industrial settings or on medical devices. As such, research into the formation and elimination of biofilms is important for many disciplines. Several new methodologies have been recently developed for, or adapted to, biofilm studies that have contributed to deeper knowledge on biofilm physiology, structure and composition. In this review, traditional and cutting-edge methods to study biofilm biomass, viability, structure, composition and physiology are addressed. Moreover, as there is a lack of consensus among the diversity of techniques used to grow and study biofilms. This review intends to remedy this, by giving a critical perspective, highlighting the advantages and limitations of several methods. Accordingly, this review aims at helping scientists in finding the most appropriate and up-to-date methods to study their biofilms.

  16. Investigation of Transverse Oscillation Method

    Udesen, Jesper; Jensen, Jørgen Arendt


    Conventional ultrasound scanners can only display the axial component of the blood velocity vector, which is a significant limitation when vessels nearly parallel to the skin surface are scanned. The transverse oscillation method (TO) overcomes this limitation by introducing a transverse...... focus depth, receive apodization, pulse length, transverse wave length, number of emissions, signal to noise ratio, and type of echo canceling filter used. Using the experimental scanner RASMUS, the performance of the TO method is evaluated. An experimental flowrig is used to create laminar parabolic...... flow in a blood mimicking fluid and the fluid is scanned under different flow-to-beam angles. The relative standard deviation on the transverse velocity estimate is found to be less than 10% for all angles between 50 deg. and 90 deg. Furthermore the TO method is evaluated in the flowrig using pulsatile...

  17. Test methods for textile composites

    Minguet, Pierre J.; Fedro, Mark J.; Gunther, Christian K.


    Various test methods commonly used for measuring properties of tape laminate composites were evaluated to determine their suitability for the testing of textile composites. Three different types of textile composites were utilized in this investigation: two-dimensional (2-D) triaxial braids, stitched uniweave fabric, and three-dimensional (3-D) interlock woven fabric. Four 2-D braid architectures, five stitched laminates, and six 3-D woven architectures were tested. All preforms used AS4 fibers and were resin-transfer-molded with Shell RSL-1895 epoxy resin. Ten categories of material properties were investigated: tension, open-hole tension, compression, open-hole compression, in-plane shear, filled-hole tension, bolt bearing, interlaminar tension, interlaminar shear, and interlaminar fracture toughness. Different test methods and specimen sizes were considered for each category of test. Strength and stiffness properties obtained with each of these methods are documented in this report for all the material systems mentioned above.

  18. Performance demonstration by ROC method

    Wessel, Hannelore; Nockemann, Christina; Tillack, Gerd-Rüdiger; Mattis, Arne


    The question of the efficiency of a material testing system is important, when a competing or advanced system appears at the market. The comparison of the different systems can be done partly by the comparison of the technical specification of the systems, but not all parameters can be expressed by measured values, especially not the influence of human inspectors. A testing system in the field of NDT - for example weld inspection - often consists of several different devices and components (radiographic film, its irradiation and development, conventional inspection with a light box, human inspector). The demonstration of the performance of such a system with similar or advanced methods can be done by a statistical method, the ROC method. This quantitative measure for testing performance allows the comparison of complex NDT systems which will be demonstrated in detail by the comparison of conventional weld inspection with inspection of welds using the digitised image of the radiographs.

  19. Advanced reliability methods - A review

    Forsyth, David S.


    There are a number of challenges to the current practices for Probability of Detection (POD) assessment. Some Nondestructive Testing (NDT) methods, especially those that are image-based, may not provide a simple relationship between a scalar NDT response and a damage size. Some damage types are not easily characterized by a single scalar metric. Other sensing paradigms, such as structural health monitoring, could theoretically replace NDT but require a POD estimate. And the cost of performing large empirical studies to estimate POD can be prohibitive. The response of the research community has been to develop new methods that can be used to generate the same information, POD, in a form that can be used by engineering designers. This paper will highlight approaches to image-based data and complex defects, Model Assisted POD estimation, and Bayesian methods for combining information. This paper will also review the relationship of the POD estimate, confidence bounds, tolerance bounds, and risk assessment.

  20. Internet experiments: methods, guidelines, metadata

    Reips, Ulf-Dietrich


    The Internet experiment is now a well-established and widely used method. The present paper describes guidelines for the proper conduct of Internet experiments, e.g. handling of dropout, unobtrusive naming of materials, and pre-testing. Several methods are presented that further increase the quality of Internet experiments and help to avoid frequent errors. These methods include the "seriousness check", "warm-up," "high hurdle," and "multiple site entry" techniques, control of multiple submissions, and control of motivational confounding. Finally, metadata from sites like WEXTOR ( and the web experiment list ( are reported that show the current state of Internet-based research in terms of the distribution of fields, topics, and research designs used.

  1. Decomposition methods for unsupervised learning

    Mørup, Morten


    This thesis presents the application and development of decomposition methods for Unsupervised Learning. It covers topics from classical factor analysis based decomposition and its variants such as Independent Component Analysis, Non-negative Matrix Factorization and Sparse Coding to their genera...... to the analysis of social network data.......This thesis presents the application and development of decomposition methods for Unsupervised Learning. It covers topics from classical factor analysis based decomposition and its variants such as Independent Component Analysis, Non-negative Matrix Factorization and Sparse Coding...... methods and clustering problems is derived both in terms of classical point clustering but also in terms of community detection in complex networks. A guiding principle throughout this thesis is the principle of parsimony. Hence, the goal of Unsupervised Learning is here posed as striving for simplicity...

  2. Deep Learning and Bayesian Methods

    Prosper Harrison B.


    Full Text Available A revolution is underway in which deep neural networks are routinely used to solve diffcult problems such as face recognition and natural language understanding. Particle physicists have taken notice and have started to deploy these methods, achieving results that suggest a potentially significant shift in how data might be analyzed in the not too distant future. We discuss a few recent developments in the application of deep neural networks and then indulge in speculation about how such methods might be used to automate certain aspects of data analysis in particle physics. Next, the connection to Bayesian methods is discussed and the paper ends with thoughts on a significant practical issue, namely, how, from a Bayesian perspective, one might optimize the construction of deep neural networks.

  3. Manufacturing method of photoelectric converter

    Yamazaki, Shunpei; Suzuki, Kunio; Fukada, Takeshi; Kanehana, Mikio


    This is a photoelectric converter wherein a photoelectromotive force is generated by utilizing the shorter wavelength side by the 1st converter and by utilizing the longer wavelength side by the 2nd converter; as a whole, wider wavelength range of light can be converted into electricity. In the 1st. converter, an electrode on the side of semi-incident surface is made transparent as well as an electrode equipped on the back of a non-mono-crystalline semiconductor. Light which passed this is introduced into the 2nd converter to generate an electromotive force. This invention especially relates with a method of forming this 2nd converter. In preparing I-type non-mono-crystalline semiconductor among the semiconductors having PIN junction, PCVD method is used by means of ECR (Electron Cyclotron Resonance) by using a hydrogen- or halogen- added Si-semiconductor instead of using expensive Ge, etc, which are common in the conventional method. (3 figs)


    Abbasova, A.A.


    Full Text Available This article is about how to the importance of selecting the optimal methods of stimulation and motivation to learn. In modern conditions it is very important that the teacher gave the students ready knowledge, and pointed the way for the acquisition of knowledge, taught to acquire knowledge. This requires the selection of effective forms of language and literature work with texts of different types and styles of speech, listening, speaking. In this regard, special attention should be given lessons of speech development. There is a special group of methods to stimulate the development of communicative competence. Among them, and the method of discussion, which is increasingly being used in the classroom in the Russian language

  5. Variational methods in molecular modeling


    This book presents tutorial overviews for many applications of variational methods to molecular modeling. Topics discussed include the Gibbs-Bogoliubov-Feynman variational principle, square-gradient models, classical density functional theories, self-consistent-field theories, phase-field methods, Ginzburg-Landau and Helfrich-type phenomenological models, dynamical density functional theory, and variational Monte Carlo methods. Illustrative examples are given to facilitate understanding of the basic concepts and quantitative prediction of the properties and rich behavior of diverse many-body systems ranging from inhomogeneous fluids, electrolytes and ionic liquids in micropores, colloidal dispersions, liquid crystals, polymer blends, lipid membranes, microemulsions, magnetic materials and high-temperature superconductors. All chapters are written by leading experts in the field and illustrated with tutorial examples for their practical applications to specific subjects. With emphasis placed on physical unders...

  6. Evaluation methods for hospital facilities

    Fronczek-Munter, Aneta


    Initial position & background: There are various methods and tools for evaluating facilities. The focus is usually on the technical building performance, function/usability or form/beauty. Examples are: Post-Occupancy Evaluation (POE) and Usability Appraisal. Nevertheless, evaluations of buildings...... according to focus areas and proposes which evaluation methods to use in different building phases of healthcare facilities. Hospital evaluations with experts and users are also considered; their subjective view on space, function, technology, usability and aesthetics. Results & solutions: This paper...... of creating buildings with enhanced usability. Additionally various evaluation methods used in hospital cases in Denmark and Norway are presented. Involvement of users is proposed, not just in defining requirements but also in co-creation/design and evaluation of solutions. The theories and preliminary...

  7. Critical review on biofilm methods

    Azeredo, Joana; F. Azevedo, Nuno; Briandet, Romain;


    into the formation and elimination of biofilms is important for many disciplines. Several new methodologies have been recently developed for, or adapted to, biofilm studies that have contributed to deeper knowledge on biofilm physiology, structure and composition. In this review, traditional and cutting-edge methods...... to study biofilm biomass, viability, structure, composition and physiology are addressed. Moreover, as there is a lack of consensus among the diversity of techniques used to grow and study biofilms. This review intends to remedy this, by giving a critical perspective, highlighting the advantages...... and limitations of several methods. Accordingly, this review aims at helping scientists in finding the most appropriate and up-to-date methods to study their biofilms....

  8. Methods of forming boron nitride

    Trowbridge, Tammy L; Wertsching, Alan K; Pinhero, Patrick J; Crandall, David L


    A method of forming a boron nitride. The method comprises contacting a metal article with a monomeric boron-nitrogen compound and converting the monomeric boron-nitrogen compound to a boron nitride. The boron nitride is formed on the same or a different metal article. The monomeric boron-nitrogen compound is borazine, cycloborazane, trimethylcycloborazane, polyborazylene, B-vinylborazine, poly(B-vinylborazine), or combinations thereof. The monomeric boron-nitrogen compound is polymerized to form the boron nitride by exposure to a temperature greater than approximately C. The boron nitride is amorphous boron nitride, hexagonal boron nitride, rhombohedral boron nitride, turbostratic boron nitride, wurzite boron nitride, combinations thereof, or boron nitride and carbon. A method of conditioning a ballistic weapon and a metal article coated with the monomeric boron-nitrogen compound are also disclosed.

  9. Optimization methods in structural design

    Rothwell, Alan


    This book offers an introduction to numerical optimization methods in structural design. Employing a readily accessible and compact format, the book presents an overview of optimization methods, and equips readers to properly set up optimization problems and interpret the results. A ‘how-to-do-it’ approach is followed throughout, with less emphasis at this stage on mathematical derivations. The book features spreadsheet programs provided in Microsoft Excel, which allow readers to experience optimization ‘hands-on.’ Examples covered include truss structures, columns, beams, reinforced shell structures, stiffened panels and composite laminates. For the last three, a review of relevant analysis methods is included. Exercises, with solutions where appropriate, are also included with each chapter. The book offers a valuable resource for engineering students at the upper undergraduate and postgraduate level, as well as others in the industry and elsewhere who are new to these highly practical techniques.Whi...

  10. Deep Learning and Bayesian Methods

    Prosper, Harrison B.


    A revolution is underway in which deep neural networks are routinely used to solve diffcult problems such as face recognition and natural language understanding. Particle physicists have taken notice and have started to deploy these methods, achieving results that suggest a potentially significant shift in how data might be analyzed in the not too distant future. We discuss a few recent developments in the application of deep neural networks and then indulge in speculation about how such methods might be used to automate certain aspects of data analysis in particle physics. Next, the connection to Bayesian methods is discussed and the paper ends with thoughts on a significant practical issue, namely, how, from a Bayesian perspective, one might optimize the construction of deep neural networks.

  11. Discretized Volumes in Numerical Methods

    Antal, Miklós


    We present two techniques novel in numerical methods. The first technique compiles the domain of the numerical methods as a discretized volume. Congruent elements are glued together to compile the domain over which the solution of a boundary value problem is sought. We associate a group and a graph to that volume. When the group is symmetry of the boundary value problem under investigation, one can specify the structure of the solution, and find out if there are equispectral volumes of a given type. The second technique uses a complex mapping to transplant the solution from volume to volume and a correction function. Equation for the correction function is given. A simple example demonstrates the feasibility of the suggested method.

  12. A Linear Iterative Unfolding Method

    Laszlo, Andras


    A frequently faced task in experimental physics is to measure the probability distribution of some quantity. Often this quantity to be measured is smeared by a non-ideal detector response or by some physical process. The procedure of removing this smearing effect from the measured distribution is called unfolding, and is a delicate problem in signal processing. Due to the numerical ill-posedness of this task, various methods were invented which, given some assumptions on the initial probability distribution, try to regularize the problem. Most of these methods definitely introduce bias on the estimate of the initial probability distribution. We propose a linear iterative method (motivated by the Neumann series / Landweber iteration known in functional analysis), which has the advantage that no assumptions on the initial probability distribution is needed, and the only regularization parameter is the stopping order of the iteration. Convergence is proved under certain quite general conditions, which hold for p...

  13. Determining distances using asteroseismic methods

    Aguirre, V Silva; Basu, S; Campante, T L; Chaplin, W J; Huber, D; Miglio, A; Serenelli, A M; WG#1, KASC


    Asteroseismology has been extremely successful in determining the properties of stars in different evolutionary stages with a remarkable level of precision. However, to fully exploit its potential, robust methods for estimating stellar parameters are required and independent verification of the results is needed. In this talk, I present a new technique developed to obtain stellar properties by coupling asteroseismic analysis with the InfraRed Flux Method. Using two global seismic observables and multi-band photometry, the technique determines masses, radii, effective temperatures, bolometric fluxes, and thus distances for field stars in a self-consistent manner. Applying our method to a sample of solar-like oscillators in the {\\it Kepler} field that have accurate {\\it Hipparcos} parallaxes, we find agreement in our distance determinations to better than 5%. Comparison with measurements of spectroscopic effective temperatures and interferometric radii also validate our results, and show that our technique can ...

  14. Supportive Music and Imagery Method

    Sumi Paik-Maier


    Full Text Available

    The Supportive Music and Imagery Method is derived from the Bonny Method of Guided Imagery and Music (BMGIM. It uses one piece of pre-recorded music that is short and simple in all musical elements and non-classical music is often used.It aims at enhancing one’s ego by supporting one’s positive resource rather than exploring problems and issues. It is containing and highly structured compared to BMGIM and it focuses on the here-and-now.

    I will introduce how the SMI method is conducted by illustrating a few case examples supervised by me and conducted by graduates and trainees of the Music and Imagery training in Korea.

  15. Spectral Methods for Numerical Relativity

    Grandclément, Philippe


    Equations arising in General Relativity are usually to complicated to be solved analytically and one has to rely on numerical methods to solve sets of coupled, partial differential, equations. Amongst the possible choices, this paper focuses on a class called spectral methods where, typically, the various functions are expanded onto sets of orthogonal polynomials or functions. A theoretical introduction on spectral expansion is first given and a particular emphasize is put on the fast convergence of the spectral approximation. We present then different approaches to solve partial differential equations, first limiting ourselves to the one-dimensional case, with one or several domains. Generalization to more dimensions is then discussed. In particular, the case of time evolutions is carefully studied and the stability of such evolutions investigated. One then turns to results obtained by various groups in the field of General Relativity by means of spectral methods. First, works which do not involve explicit t...

  16. The Generalised Phase Contrast Method

    Glückstad, Jesper

    An analytic framework and a complete description for the design and optimisation of on-axis centred spatially filtering common path systems are presented. The Generalised Phase Contrast method is derived and introduced as the common denominator for these systems basically extending Zernike....... Optimal conditions for visibility, peak irradiance and accuracy are derived and shown to be perfectly in line with empirical results from the literature. New graphic methods for advanced analysis purposes are demonstrated supporting these conclusions as well as providing new tools for innovative filter...... designs and parameter settings. Finally, a number of original applications facilitated by the parallel light-beam encoding of the Generalised Phase Contrast method are briefly outlined. These include among others, wavefront sensing and generation, advanced usercontrolled optical micro...

  17. Selection Method for COTS Systems

    Hedman, Jonas; Andersson, Bo


    Historically, organizations developed their information systems in-house. Today, a large portion of information systems development is based on the acquisition of pre-made information systems, so-called commercially off-the-shelf (COTS) systems. This approach for developing information systems...... requires new skills and methods supporting the process of evaluating and selecting information systems. This paper presents a method for selecting COTS systems. The method includes the following phases: problem framing, requirements and appraisal, and selection of systems. The idea and distinguishing...... of approaching the selection of COTS systems as viewing them as a ‘means’ to reach organizational ‘ends’ is different from the mainstream views of information systems development, namely the view that sees information systems development as a problem-solving process, and the underlying ontological view in other...

  18. Vulnerability of the clinical method

    José Carlos Hernández Aragonés


    Full Text Available This article is aimed at outlining the general aspects that undermine the use of the clinical method in everyday medical practice and also at exposing those that cause a negative effect on the use of the various steps leading to the correct diagnosis and treatment of a patient. A presentation is made on the issues and situations that may contribute not to take into account the clinical method and the requirements for its implementation. Finally, it is concluded that the importance and appropriate management of the clinical method is not still widely known and that the decline of the doctor-patient relationship is a key element that hinders its application.

  19. Robust statistical methods with R

    Jureckova, Jana


    Robust statistical methods were developed to supplement the classical procedures when the data violate classical assumptions. They are ideally suited to applied research across a broad spectrum of study, yet most books on the subject are narrowly focused, overly theoretical, or simply outdated. Robust Statistical Methods with R provides a systematic treatment of robust procedures with an emphasis on practical application.The authors work from underlying mathematical tools to implementation, paying special attention to the computational aspects. They cover the whole range of robust methods, including differentiable statistical functions, distance of measures, influence functions, and asymptotic distributions, in a rigorous yet approachable manner. Highlighting hands-on problem solving, many examples and computational algorithms using the R software supplement the discussion. The book examines the characteristics of robustness, estimators of real parameter, large sample properties, and goodness-of-fit tests. It...

  20. Method-MS. Final report

    Skipperud, L.; Popic, J.M. (Norwegian Univ. of Life Science (UMB), Isotope Lab. (Norway)); Roos, P. (Technical Univ. of Denmark, Risoe National Lab. for Sustainable Energy, Roskilde (Denmark)); Salminen, S. (Univ. of Helsinki (UH) (Finland)); Nygren, U. (Swedish Defence Research Agency (FOI) (Sweden)); Sigmarsson, O.; Palsson, S.E. (Univ. of Iceland/Icelandic Radiation Protection Institute (Iceland))


    Radiometric determination methods, such as alpha spectrometry require long counting times when low activities are to be determined. Mass spectrometric techniques as Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Thermal Ionisation Mass Spectrometry (TIMS) and Accelerator Mass Spectrometry (AMS) have shown several advantages compared to traditional methods when measuring long-lived radionuclides. Mass spectrometric methods for determination of very low concentrations of elemental isotopes, and thereby isotopic ratios, have been developed using a variety of ion sources. Although primarily applied to the determination of the lighter stable element isotopes and radioactive isotopes in geological studies, the techniques can equally well be applied to the measurement of activity concentrations of long-lived low-level radionuclides in various samples using 'isotope dilution' methods such as those applied in inductively coupled plasma mass spectrometry (ICP-MS). Due to the low specific activity of long-lived radionuclides, many of these are more conveniently detected using mass spectrometric techniques. Mass spectrometry also enables the individual determination of Pu-239 and Pu-240, which cannot be obtained by alpha spectrometry. Inductively Coupled Plasma Mass Spectrometry (ICP-MS) are rapidly growing techniques for the ultra-trace analytical determination of stable and long-lived isotopes and have a wide potential within environmental science, including ecosystem tracers and radio ecological studies. Such instrumentation, of course needs good radiochemical separation, to give best performance. The objectives of the project is to identify current needs and problems within low-level determination of long-lived radioisotopes by ICP-MS, to perform intercalibration and development and improvement of ICP-MS methods for the measurement of radionuclides and isotope ratios and to develop new methods based on modified separation chemistry applied to new

  1. Modern methods of image reconstruction.

    Puetter, R. C.

    The author reviews the image restoration or reconstruction problem in its general setting. He first discusses linear methods for solving the problem of image deconvolution, i.e. the case in which the data are a convolution of a point-spread function and an underlying unblurred image. Next, non-linear methods are introduced in the context of Bayesian estimation, including maximum likelihood and maximum entropy methods. Then, the author discusses the role of language and information theory concepts for data compression and solving the inverse problem. The concept of algorithmic information content (AIC) is introduced and is shown to be crucial to achieving optimal data compression and optimized Bayesian priors for image reconstruction. The dependence of the AIC on the selection of language then suggests how efficient coordinate systems for the inverse problem may be selected. The author also introduced pixon-based image restoration and reconstruction methods. The relation between image AIC and the Bayesian incarnation of Occam's Razor is discussed, as well as the relation of multiresolution pixon languages and image fractal dimension. Also discussed is the relation of pixons to the role played by the Heisenberg uncertainty principle in statistical physics and how pixon-based image reconstruction provides a natural extension to the Akaike information criterion for maximum likelihood. The author presents practical applications of pixon-based Bayesian estimation to the restoration of astronomical images. He discusses the effects of noise, effects of finite sampling on resolution, and special problems associated with spatially correlated noise introduced by mosaicing. Comparisons to other methods demonstrate the significant improvements afforded by pixon-based methods and illustrate the science that such performance improvements allow.

  2. Accurate, meshless methods for magnetohydrodynamics

    Hopkins, Philip F.; Raives, Matthias J.


    Recently, we explored new meshless finite-volume Lagrangian methods for hydrodynamics: the `meshless finite mass' (MFM) and `meshless finite volume' (MFV) methods; these capture advantages of both smoothed particle hydrodynamics (SPH) and adaptive mesh refinement (AMR) schemes. We extend these to include ideal magnetohydrodynamics (MHD). The MHD equations are second-order consistent and conservative. We augment these with a divergence-cleaning scheme, which maintains nabla \\cdot B≈ 0. We implement these in the code GIZMO, together with state-of-the-art SPH MHD. We consider a large test suite, and show that on all problems the new methods are competitive with AMR using constrained transport (CT) to ensure nabla \\cdot B=0. They correctly capture the growth/structure of the magnetorotational instability, MHD turbulence, and launching of magnetic jets, in some cases converging more rapidly than state-of-the-art AMR. Compared to SPH, the MFM/MFV methods exhibit convergence at fixed neighbour number, sharp shock-capturing, and dramatically reduced noise, divergence errors, and diffusion. Still, `modern' SPH can handle most test problems, at the cost of larger kernels and `by hand' adjustment of artificial diffusion. Compared to non-moving meshes, the new methods exhibit enhanced `grid noise' but reduced advection errors and diffusion, easily include self-gravity, and feature velocity-independent errors and superior angular momentum conservation. They converge more slowly on some problems (smooth, slow-moving flows), but more rapidly on others (involving advection/rotation). In all cases, we show divergence control beyond the Powell 8-wave approach is necessary, or all methods can converge to unphysical answers even at high resolution.

  3. Space Radiation Transport Methods Development

    Wilson, J.; Tripathi, R.; Qualls, G.; Cucinotta, F.; Prael, R.; Norbury, J.

    Early space radiation shield code development relied on Monte Carlo methods for proton, neutron and pion transport and made important contributions to the space program. More recently Monte Carlo code LAHET has been upgraded to include high-energy multiple-charged light ions for GCR simulations and continues to be expanded in capability. To compensate for low computational efficiency, Monte Carlo methods have resorted to restricted one-dimensional problems leading to imperfect representations of appropriate boundary conditions. Even so, intensive computational requirements resulted and shield evaluation was made near the end of the design process and resolving shielding issues usually had a negative impact on the design. We evaluate the implications of these common one-dimensional assumptions on the evaluation of the Shuttle internal radiation field. Improved spacecraft shield design requires early entry of radiation constraints into the design process to maximize performance and minimize costs. As a result, we have been investigating high-speed computational procedures to allow shield analysis from the preliminary design concepts to the final design. In particular, we will discuss the progress towards a full three-dimensional and computationally efficient deterministic code for which the current HZETRN evaluates the lowest order asymptotic term. HZETRN is the first deterministic solution to the Boltzmann equation allowing field mapping within the International Space Station (ISS) in tens of minutes using standard Finite Element Method (FEM) geometry common to engineering design practice enabling development of integrated multidisciplinary design optimization methods. A single ray trace in ISS FEM geometry requires 14 milliseconds and severely limits application of Monte Carlo methods to such engineering models. A potential means of improving the Monte Carlo efficiency in coupling to spacecraft geometry is given in terms of reconfigurable computing and could be

  4. The Diffraction Response Interpolation Method

    Jespersen, Søren Kragh; Wilhjelm, Jens Erik; Pedersen, Peder C.


    medium, is presented. The DRIM is based on the velocity potential impulseresponse method, adapted to pulse-echo applications by the use of acoustical reciprocity. Specifically, the DRIM operates bydividing the reflector surface into planar elements, finding the diffraction response at the corners...... of the elements, calculating theresponse integrated over the surface element by time-domain convolutions with analytically determined filters, and summing theresponses from the individual surface elements. As the method is based on linearity, effects such as shadowing, higher-orderdiffraction, nonlinear...

  5. Melnikov's method in String Theory

    Asano, Yuhma; Yoshida, Kentaroh


    Melnikov's method is an analytical way to show the existence of classical chaos generated by a Smale horseshoe. It is a powerful technique, though its applicability is somewhat limited. In this paper, we present a solution of type IIB supergravity to which Melnikov's method is applicable. This is a brane-wave type deformation of the AdS$_5\\times$S$^5$ background. By employing two reduction ans\\"atze, we study two types of coupled pendulum-oscillator systems. Then the Melnikov function is computed for each of the systems by following the standard way of Holmes and Marsden and the existence of chaos is shown analytically.

  6. Advanced method for oligonucleotide deprotection

    Surzhikov, Sergey A.; Timofeev, Edward N.; Chernov, Boris K.; Golova, Julia B.; Mirzabekov, Andrei D.


    A new procedure for rapid deprotection of synthetic oligodeoxynucleotides has been developed. While all known deprotection methods require purification to remove the residual protective groups (e.g. benzamide) and insoluble silicates, the new procedure based on the use of an ammonia-free reagent mixture allows one to avoid the additional purification steps. The method can be applied to deprotect the oligodeoxynucleotides synthesized by using the standard protected nucleoside phosphoramidites dGiBu, dCBz and dABz. PMID:10734206

  7. Advanced method for oligonucleotide deprotection.

    Surzhikov, S. A.; Timofeev, E. N.; Chernov, B. K.; Golova, J. B.; Mirzabekov, A. D.; Biochip Technology Center; Engelhardt Inst. of Molecular Biology


    A new procedure for rapid deprotection of synthetic oligodeoxynucleotides has been developed. While all known deprotection methods require purification to remove the residual protective groups (e.g. benzamide) and insoluble silicates, the new procedure based on the use of an ammonia-free reagent mixture allows one to avoid the additional purification steps. The method can be applied to deprotect the oligodeoxynucleotides synthesized by using the standard protected nucleoside phosphoramidites dG{sup iBu}, dC{sup Bz} and dA{sup Bz}.

  8. Computerized triaxial test control methods

    Sabaliauskas, Tomas; Ibsen, Lars Bo


    Liquefaction induced nonlinearities in soil make triaxial cyclic testing problematic. Some solutions are presented in this paper. Single diameter height, smooth boundary condition triaxial tests perform well at relatively high axial strains, even while liquefying for many loading cycles. Testing...... capabilities of the setup are extended by using a programmable hydraulic piston with real time feedback loops. The control methods provided by the controller mimic those applied in computer simulations. Force control, displacement control or a combination of both can be used. Single diameter height sample...... control methods provide access to testing both direct and inverse stiffness matrix response as well as to observe strain creep and stress relaxation directly....

  9. Qualitative methods in theoretical physics

    Maslov, Dmitrii


    This book comprises a set of tools which allow researchers and students to arrive at a qualitatively correct answer without undertaking lengthy calculations. In general, Qualitative Methods in Theoretical Physics is about combining approximate mathematical methods with fundamental principles of physics: conservation laws and symmetries. Readers will learn how to simplify problems, how to estimate results, and how to apply symmetry arguments and conduct dimensional analysis. A comprehensive problem set is included. The book will appeal to a wide range of students and researchers.

  10. Method for analyzing microbial communities

    Zhou, Jizhong [Oak Ridge, TN; Wu, Liyou [Oak Ridge, TN


    The present invention provides a method for quantitatively analyzing microbial genes, species, or strains in a sample that contains at least two species or strains of microorganisms. The method involves using an isothermal DNA polymerase to randomly and representatively amplify genomic DNA of the microorganisms in the sample, hybridizing the resultant polynucleotide amplification product to a polynucleotide microarray that can differentiate different genes, species, or strains of microorganisms of interest, and measuring hybridization signals on the microarray to quantify the genes, species, or strains of interest.

  11. Optimization methods for logical inference

    Chandru, Vijay


    Merging logic and mathematics in deductive inference-an innovative, cutting-edge approach. Optimization methods for logical inference? Absolutely, say Vijay Chandru and John Hooker, two major contributors to this rapidly expanding field. And even though ""solving logical inference problems with optimization methods may seem a bit like eating sauerkraut with chopsticks. . . it is the mathematical structure of a problem that determines whether an optimization model can help solve it, not the context in which the problem occurs."" Presenting powerful, proven optimization techniques for logic in

  12. Method of moments in electromagnetics

    Gibson, Walton C


    Responding to the need for a clear, up-to-date introduction to the field, The Method of Moments in Electromagnetics explores surface integral equations in electromagnetics and presents their numerical solution using the method of moments (MOM) technique. It provides the numerical implementation aspects at a nuts-and-bolts level while discussing integral equations and electromagnetic theory at a higher level. The author covers a range of topics in this area, from the initial underpinnings of the MOM to its current applications. He first reviews the frequency-domain electromagnetic theory and t

  13. Statistical Methods for Fuzzy Data

    Viertl, Reinhard


    Statistical data are not always precise numbers, or vectors, or categories. Real data are frequently what is called fuzzy. Examples where this fuzziness is obvious are quality of life data, environmental, biological, medical, sociological and economics data. Also the results of measurements can be best described by using fuzzy numbers and fuzzy vectors respectively. Statistical analysis methods have to be adapted for the analysis of fuzzy data. In this book, the foundations of the description of fuzzy data are explained, including methods on how to obtain the characterizing function of fuzzy m

  14. Methods for estimating the semivariogram

    Lophaven, Søren Nymand; Carstensen, Niels Jacob; Rootzen, Helle


    . In the existing literature various methods for modelling the semivariogram have been proposed, while only a few studies have been made on comparing different approaches. In this paper we compare eight approaches for modelling the semivariogram, i.e. six approaches based on least squares estimation...... maximum likelihood performed better than the least squares approaches. We also applied maximum likelihood and least squares estimation to a real dataset, containing measurements of salinity at 71 sampling stations in the Kattegat basin. This showed that the calculation of spatial predictions...... is insensitive to the choice of estimation method, but also that the uncertainties of predictions were reduced when applying maximum likelihood....

  15. Twin-Foucault imaging method

    Harada, Ken


    A method of Lorentz electron microscopy, which enables observation two Foucault images simultaneously by using an electron biprism instead of an objective aperture, was developed. The electron biprism is installed between two electron beams deflected by 180° magnetic domains. Potential applied to the biprism deflects the two electron beams further, and two Foucault images with reversed contrast are then obtained in one visual field. The twin Foucault images are able to extract the magnetic domain structures and to reconstruct an ordinary electron micrograph. The developed Foucault method was demonstrated with a 180° domain structure of manganite La0.825Sr0.175MnO3.

  16. New disinfection and sterilization methods.

    Rutala, W. A.; Weber, D. J.


    New disinfection methods include a persistent antimicrobial coating that can be applied to inanimate and animate objects (Surfacine), a high-level disinfectant with reduced exposure time (ortho-phthalaldehyde), and an antimicrobial agent that can be applied to animate and inanimate objects (superoxidized water). New sterilization methods include a chemical sterilization process for endoscopes that integrates cleaning (Endoclens), a rapid (4-hour) readout biological indicator for ethylene oxide sterilization (Attest), and a hydrogen peroxide plasma sterilizer that has a shorter cycle time and improved efficacy (Sterrad 50). PMID:11294738

  17. Advances in energy harvesting methods

    Elvin, Niell


    Advances in Energy Harvesting Methods presents a state-of-the-art understanding of diverse aspects of energy harvesting with a focus on: broadband energy conversion, new concepts in electronic circuits, and novel materials. This book covers recent advances in energy harvesting using different transduction mechanisms; these include methods of performance enhancement using nonlinear effects, non-harmonic forms of excitation and non-resonant energy harvesting, fluidic energy harvesting, and advances in both low-power electronics as well as  material science. The contributors include a brief liter

  18. Stochastic methods in quantum mechanics

    Gudder, Stanley P


    Practical developments in such fields as optical coherence, communication engineering, and laser technology have developed from the applications of stochastic methods. This introductory survey offers a broad view of some of the most useful stochastic methods and techniques in quantum physics, functional analysis, probability theory, communications, and electrical engineering. Starting with a history of quantum mechanics, it examines both the quantum logic approach and the operational approach, with explorations of random fields and quantum field theory.The text assumes a basic knowledge of fun

  19. Combustion synthesis method and products

    Holt, J.B.; Kelly, M.


    Disclosed is a method of producing dense refractory products, comprising: (a) obtaining a quantity of exoergic material in powder form capable of sustaining a combustion synthesis reaction; (b) removing absorbed water vapor therefrom; (c) cold-pressing said material into a formed body; (d) plasma spraying said formed body with a molten exoergic material to form a coat thereon; and (e) igniting said exoergic coated formed body under an inert gas atmosphere and pressure to produce self-sustained combustion synthesis. Also disclosed are products produced by the method.

  20. Offshore fouling:investigation methods

    YAN Tao; YAN Wenxia; DONG Yu; LIANG Guanhe; YAN Yan; WANG Huajie


    On the hasis of the reason that the offshore oil development areas in the northern South China Sea are at greater depth,more hazardous conditions and distance from shore, the methods and technologies used in coastal waters are not feasible because of the higher risk of losing investigation equipment or facilities. A series of methods and technologies for offshore fouling investigation that have been successfully applied is given in detail and it is hoped that the experience can be helpful for further studies.

  1. Data mining methods and applications

    Lawrence, Kenneth D; Klimberg, Ronald K


    With today's information explosion, many organizations are now able to access a wealth of valuable data. Unfortunately, most of these organizations find they are ill-equipped to organize this information, let alone put it to work for them. Gain a Competitive Advantage Employ data mining in research and forecasting Build models with data management tools and methodology optimization Gain sophisticated breakdowns and complex analysis through multivariate, evolutionary, and neural net methodsLearn how to classify data and maintain qualityTransform Data into Business Acumen Data Mining Methods and

  2. Statistical methods for ranking data

    Alvo, Mayer


    This book introduces advanced undergraduate, graduate students and practitioners to statistical methods for ranking data. An important aspect of nonparametric statistics is oriented towards the use of ranking data. Rank correlation is defined through the notion of distance functions and the notion of compatibility is introduced to deal with incomplete data. Ranking data are also modeled using a variety of modern tools such as CART, MCMC, EM algorithm and factor analysis. This book deals with statistical methods used for analyzing such data and provides a novel and unifying approach for hypotheses testing. The techniques described in the book are illustrated with examples and the statistical software is provided on the authors’ website.

  3. On philosophical subjects and methods

    Peng Fuchun


    With the consideration of some issues in contemporary philosophy,this thesis attempts to analyze being,thinking and language as philosophical subjects,and clear up the multiple meanings for each of them.It will also inquire the traditional methods in both Chinese and Western philosophy,and those in contemporary thinking.Finally,it puts forward a theory of"the critique without principles".The thesis aims to explore a new way to solve the problems of contemporary philosophy by changing its subjects and methods.

  4. Evaluation methods for hospital projects.

    Buelow, Janet R; Zuckweiler, Kathryn M; Rosacker, Kirsten M


    The authors report the findings of a survey of hospital managers on the utilization of various project selection and evaluation methodologies. The focus of the analysis was the empirical relationship between a portfolio of project evaluation(1) methods actually utilized for a given project and several measures of perceived project success. The analysis revealed that cost-benefit analysis and top management support were the two project evaluation methods used most often by the hospital managers. The authors' empirical assessment provides evidence that top management support is associated with overall project success.

  5. One method of storing information

    Titov, Oleg


    Formulate the problem as follows. Split a file into n pieces so that it can be restored without any m parts (1<=m<=n). Such problems are called problems secret sharing. There exists a set of methods for solving such problems, but they all require a fairly large number of calculations applied to the problem posed above. The proposed method does not require calculations, and requires only the operations of the division of the file into equal (nearly equal) parts and gluing them in a certain order in one or more files.

  6. Discussion on prosthodontics teaching methods

    Guanwu Rao


    Prosthodontics is one of the main courses of oral clinical oral compulsory medical students, and it is a highly practical skill required for the course. In the teaching process, we not only should pay attention to the teaching of theoretical knowledge, but should strengthen the training of practical skills. In order to improve the teaching quality of experimental teaching and students' practical ability, we reform the method of experimental evaluation in prosthodontics experimental teaching, explore the establishment of a reasonable, applicable and effective experiment prosthodontics assessment methods.

  7. Method of constrained global optimization

    Altschuler, E.L.; Williams, T.J.; Ratner, E.R.; Dowla, F.; Wooten, F. (Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551 (United States) Department of Applied Physics, Stanford University, Stanford, California 94305 (United States) Department of Applied Science, University of California, Davis/Livermore, P.O. Box 808, Livermore, California 94551 (United States))


    We present a new method for optimization: constrained global optimization (CGO). CGO iteratively uses a Glauber spin flip probability and the Metropolis algorithm. The spin flip probability allows changing only the values of variables contributing excessively to the function to be minimized. We illustrate CGO with two problems---Thomson's problem of finding the minimum-energy configuration of unit charges on a spherical surface, and a problem of assigning offices---for which CGO finds better minima than other methods. We think CGO will apply to a wide class of optimization problems.

  8. Pulsed ultrasonic stir welding method

    Ding, R. Jeffrey (Inventor)


    A method of performing ultrasonic stir welding uses a welding head assembly to include a plate and a rod passing through the plate. The rod is rotatable about a longitudinal axis thereof. In the method, the rod is rotated about its longitudinal axis during a welding operation. During the welding operation, a series of on-off ultrasonic pulses are applied to the rod such that they propagate parallel to the rod's longitudinal axis. At least a pulse rate associated with the on-off ultrasonic pulses is controlled.

  9. Method for in vitro recombination

    Gibson, Daniel Glenn; Smith, Hamilton O


    The present invention relates to an in vitro method, using isolated protein reagents, for joining two double-stranded (ds) DNA molecules of interest, wherein the distal region of the first DNA molecule and the proximal region of the second DNA molecule share a region of sequence identity. The method allows the joining of a number of DNA fragments, in a predetermined order and orientation, without the use of restriction enzymes. It can be used, e.g., to join synthetically produced sub-fragments of a gene or genome of interest.

  10. Extrapolation methods theory and practice

    Brezinski, C


    This volume is a self-contained, exhaustive exposition of the extrapolation methods theory, and of the various algorithms and procedures for accelerating the convergence of scalar and vector sequences. Many subroutines (written in FORTRAN 77) with instructions for their use are provided on a floppy disk in order to demonstrate to those working with sequences the advantages of the use of extrapolation methods. Many numerical examples showing the effectiveness of the procedures and a consequent chapter on applications are also provided - including some never before published results and applicat

  11. Statistical methods in nonlinear dynamics

    K P N Murthy; R Harish; S V M Satyanarayana


    Sensitivity to initial conditions in nonlinear dynamical systems leads to exponential divergence of trajectories that are initially arbitrarily close, and hence to unpredictability. Statistical methods have been found to be helpful in extracting useful information about such systems. In this paper, we review briefly some statistical methods employed in the study of deterministic and stochastic dynamical systems. These include power spectral analysis and aliasing, extreme value statistics and order statistics, recurrence time statistics, the characterization of intermittency in the Sinai disorder problem, random walk analysis of diffusion in the chaotic pendulum, and long-range correlations in stochastic sequences of symbols.

  12. Evaluation of profanity deobfuscation methods

    Gustavo Laboreiro


    Full Text Available Cursing is a form of expression that is noted by its intensity. When someone uses this form of expression they are emitting a spontaneous and raw form of opinion, usually suppressed for the ``mild ways'' and sensitive people. As it happens, this sort of expression is also valuable when doing some sort of opinion mining and sentiment analysis, now a routine task across the social networks. Therefore in this work we try to evaluate the methods that allow the recovery of this forms of expression, disguised through obfuscation methods, often as a way to escape automatic censorship.


    XIU Naihua; WU Fang


    In this paper, a hybrid method for linear programming is established.Its search direction is defined as a combination of two directions insimplex method and affine-scaling interior point method.The method is proven to have some promising convergence properties.The relation among the new method, the simplex method and the affine-scalinginteriorpoint method is discussed.

  14. Isogeometric methods for numerical simulation

    Bordas, Stéphane


    The book presents the state of the art in isogeometric modeling and shows how the method has advantaged. First an introduction to geometric modeling with NURBS and T-splines is given followed by the implementation into computer software. The implementation in both the FEM and BEM is discussed.

  15. Energy Expenditure and Intake Methods

    Westerterp, K.R.


    The main components of total energy expenditure are energy expenditure for maintenance or basal metabolic rate, the thermic effect of food or diet-induced energy expenditure (DEE), and the energy cost of physical activity or activity-induced energy expenditure (AEE). This chapter describes methods t

  16. Linear methods in band theory

    Andersen, O. Krogh


    of Korringa-Kohn-Rostoker, linear-combination-of-atomic-orbitals, and cellular methods; the secular matrix is linear in energy, the overlap integrals factorize as potential parameters and structure constants, the latter are canonical in the sense that they neither depend on the energy nor the cell volume...

  17. Subspace Methods for Eigenvalue Problems

    Hochstenbach, Michiel Erik


    This thesis treats a number of aspects of subspace methods for various eigenvalue problems. Vibrations and their corresponding eigenvalues (or frequencies) arise in science, engineering, and daily life. Matrix eigenvalue problems come from a large number of areas, such as chemistry, mechanics, dyn

  18. Microleakage and its measurement methods

    Siyadat H


    Full Text Available Microkeakage is one of the most important factors in restoration longevity. Microleakage can"nlead to recurrent caries, marginal fracture, marginal discoloration and tooth sensitivity. Several methods"nhave been used for in-vitro measurement of microleakage. The present study is a review of the articles,"nfrom 1967 to 1999, which have been present in Medline.

  19. Method for synthesizing carbon nanotubes

    Fan, Hongyou


    A method for preparing a precursor solution for synthesis of carbon nanomaterials, where a polar solvent is added to at least one block copolymer and at least one carbohydrate compound, and the precursor solution is processed using a self-assembly process and subsequent heating to form nanoporous carbon films, porous carbon nanotubes, and porous carbon nanoparticles.

  20. CSM parallel structural methods research

    Storaasli, Olaf O.


    Parallel structural methods, research team activities, advanced architecture computers for parallel computational structural mechanics (CSM) research, the FLEX/32 multicomputer, a parallel structural analyses testbed, blade-stiffened aluminum panel with a circular cutout and the dynamic characteristics of a 60 meter, 54-bay, 3-longeron deployable truss beam are among the topics discussed.

  1. Statistical methods for bioimpedance analysis

    Christian Tronstad


    Full Text Available This paper gives a basic overview of relevant statistical methods for the analysis of bioimpedance measurements, with an aim to answer questions such as: How do I begin with planning an experiment? How many measurements do I need to take? How do I deal with large amounts of frequency sweep data? Which statistical test should I use, and how do I validate my results? Beginning with the hypothesis and the research design, the methodological framework for making inferences based on measurements and statistical analysis is explained. This is followed by a brief discussion on correlated measurements and data reduction before an overview is given of statistical methods for comparison of groups, factor analysis, association, regression and prediction, explained in the context of bioimpedance research. The last chapter is dedicated to the validation of a new method by different measures of performance. A flowchart is presented for selection of statistical method, and a table is given for an overview of the most important terms of performance when evaluating new measurement technology.

  2. Dutch Architecture with Landscape Methods

    Jauslin, D.


    14 Project Documentations and Analysis of Dutch Architecture with Landscape Methods. MVRDV Villa VPRO, Powerhouse Company Villa 1, Herman Herzberger Coda Museum, NL Architects Basket Ba, SeARCH Posbank Pavillion, Wiel Arets Hedge House, OMA Kunsthal and Educatorium, Maaskant Johnson Wax, Diller & Sc

  3. An adjustable contracted CI method

    王育彬; 甘正汀; 苏克和; 文振翼


    A new contracted CI scheme——adjustable contracted CI scheme——is presented and programed. The efficiency of this scheme is tested by some example calculations. The result shows that the application of the new scheme is flexible and the correlation energy loss is lower than that of the original externally contracted CI method.

  4. Computational methods for fluid dynamics

    Ferziger, Joel H


    In its 3rd revised and extended edition the book offers an overview of the techniques used to solve problems in fluid mechanics on computers and describes in detail those most often used in practice. Included are advanced methods in computational fluid dynamics, like direct and large-eddy simulation of turbulence, multigrid methods, parallel computing, moving grids, structured, block-structured and unstructured boundary-fitted grids, free surface flows. The 3rd edition contains a new section dealing with grid quality and an extended description of discretization methods. The book shows common roots and basic principles for many different methods. The book also contains a great deal of practical advice for code developers and users, it is designed to be equally useful to beginners and experts. The issues of numerical accuracy, estimation and reduction of numerical errors are dealt with in detail, with many examples. A full-feature user-friendly demo-version of a commercial CFD software has been added, which ca...

  5. Training 101: Choose Your Method.

    Rae, Leslie


    Discusses a variety of training methods including mentoring, lecture, video, computer assisted, and simulation. Suggests basic approaches to on-the-job training and tools to supplement the process. A chart compares 11 training technologies in terms of settings, interactivity, development time, costs, advantages, and disadvantages. (JOW)

  6. Neurolinguistics Programming: Method or Myth?

    Gumm, W. B.; And Others


    The preferred modality by which 50 right-handed female college students encoded experience was assessed by recordings of conjugate eye movements, content analysis of the subject's verbal report, and the subject's self-report. Kappa analyses failed to reveal any agreement of the three assessment methods. (Author)




    Full Text Available The article is devoted to the methods of investigation of locative elements. Sentence analysis with locative elements is taken according to the results of component analysis in the system of contradicting – opposition. More over the article is full of examples related to the description of various syntactic units.

  8. Methods for evaluating information sources

    Hjørland, Birger


    . Reading a text is often not a simple process. All the methods discussed here are steps on the way on learning how to read, understand, and criticize texts. According to hermeneutics it involves the subjectivity of the reader, and that subjectivity is influenced, more or less, by different theoretical...

  9. Low level TOC measurement method

    Ekechukwu, Amy A.


    A method for the determination of total organic carbon in an aqueous sample by trapping the organic matter on a sorbent which is carbon free and analyzing the sorbent by combustion and determination of total CO.sub.2 by IR.

  10. Method of doping organic semiconductors

    Kloc, Christian Leo [Constance, DE; Ramirez, Arthur Penn [Summit, NJ; So, Woo-Young [New Providence, NJ


    A method includes the steps of forming a contiguous semiconducting region and heating the region. The semiconducting region includes polyaromatic molecules. The heating raises the semiconducting region to a temperature above room temperature. The heating is performed in the presence of a dopant gas and the absence of light to form a doped organic semiconducting region.

  11. Present status of processing method

    Kosako, Kazuaki [Sumitomo Atomic Energy Industries Ltd., Tokyo (Japan)


    Present status of processing method for a high-energy nuclear data file was examined. The NJOY94 code is the only one available to the processing. In Japan, present processing used NJOY94 is orienting toward the production of traditional cross section library, because a high-energy transport code using a high-energy cross section library is indistinct. (author)

  12. Adjunct methods for caries detection

    Twetman, Svante; Axelsson, Susanna Bihari; Dahlén, Gunnar


    Abstract Objective. To assess the diagnostic accuracy of adjunct methods used to detect and quantify dental caries. Study design. A systematic literature search for relevant papers was conducted with pre-determined inclusion and exclusion criteria. Abstracts and full text articles were assessed i...

  13. Method of oxidizing an alcohol

    Dijksman, A.; Arends, I.W.C.E.; Sheldon, R.A.


    The invention relates to a method of oxidizing an alcohol to form an aldehyde or ketone using a ruthenium ion and oxygen in the presence of a substantially stable N-O free radical compound, wherein two atoms bound to the nitrogen atom are not themselves hydrogen carriers. It has been found that with

  14. Methods to study postprandial lipemia

    Ooi, Teik Chye; Nordestgaard, Børge G


    such as the amount and type of food consumed, and (b) endogenous factors such as the metabolic/genetic status of the subjects, on PPL. To study PPL appropriately, different methods are used to suit the study goal. This paper provides an overview of the methodological aspects of PPL testing. It deals with markers...

  15. Can Scientific Method Be Taught?

    Phillips, D. C.


    Discussion of changes in science education and scientific literacy is presented in the form of a dialog between the author and his alter ego. Structure of science, myths, facts, methods, and critical rationality are considered. Suggests that scientific principles once considered basic and unchanging are giving way to critical thinking. (DH)

  16. The reflexive case study method

    Rittenhofer, Iris


    This paper extends the international business research on small to medium-sized enterprises (SME) at the nexus of globalization. Based on a conceptual synthesis across disciplines and theoretical perspectives, it offers management research a reflexive method for case study research of postnational...

  17. Statistical methods in spatial genetics

    Guillot, Gilles; Leblois, Raphael; Coulon, Aurelie


    to keep abreast with the latest methodological developments, we review the statistical toolbox available to analyse population genetic data in a spatially explicit framework. We mostly focus on statistical concepts but also discuss practical aspects of the analytical methods, highlighting not only...... the potential of various approaches but also methodological pitfalls....

  18. Research Methods in Interlanguage Pragmatics.

    Kasper, Gabriele; Dahl, Merete


    A review of data collection methods used in 39 studies of interlanguage pragmatics, focusing on the validity of different types of data resulting from discourse completion, role play, observation of authentic speech, and multiple approaches, concludes that caution is needed in determining the true validity of the collected data. (72 references)…

  19. Thermochemical reactor systems and methods

    Lipinski, Wojciech; Davidson, Jane Holloway; Chase, Thomas Richard


    Thermochemical reactor systems that may be used to produce a fuel, and methods of using the thermochemical reactor systems, utilizing a reactive cylindrical element, an optional energy transfer cylindrical element, an inlet gas management system, and an outlet gas management system.

  20. Method of steering a vehicle

    Della Penna, M.; Van Passen, M.M.; Abbink, D.A.; Mulder, M.


    Vehicle and method of steering such a vehicle, wherein the vehicle has a steering wheel and steerable driving wheels and a transfer system for converting steering wheel actions to a steering angle of the steerable driving wheels, and wherein the transfer system is provided with a predefined stiffnes