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Sample records for aberto ao ar

  1. Do Universo Privado ao Espaço Aberto, do Espaço Aberto ao Universo Privado - Recepção e Gênese de L´Étranger de Albert Camus

    Directory of Open Access Journals (Sweden)

    Samara Geske

    2009-10-01

    Full Text Available Este artigo pretende traçar linhas gerais sobre a recepção e a gênese de L’Étranger , passando pelo universo privado dos primeiros leitores do manuscrito até chegar ao espaço aberto de seus primeiros críticos, para do espaço aberto da obra publicada retornar o universo privado do processo de criação do romance.

  2. Impactos do uso de climatização artificial na percepção térmica em espaços abertos no centro do Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    Eduardo Leite Krüger

    Full Text Available Resumo Estudos de percepção térmica em espaços abertos são fundamentais para um planejamento urbano climaticamente orientado. O presente artigo investiga a percepção térmica de usuários de espaços abertos no Centro da cidade do Rio de Janeiro, com o objetivo de analisar o impacto do uso prolongado de ar-condicionado nos votos de sensação e preferência térmicas. As respostas obtidas por meio de entrevistas estruturadas são comparadas a índices de conforto em espaços abertos (PET e UTCI, agrupando-se as respostas segundo a utilização ou não de climatização artificial, conforme reportado pelos entrevistados. As campanhas de monitoramento foram realizadas em períodos de verão entre 2012 e 2015. A organização semiexperimental da pesquisa envolveu a permanência dos equipamentos e pesquisadores em um único ponto por campanha, durante o período de 10 às 15 horas. Uma estação meteorológica Davis Vantage Pro2 foi utilizada para a coleta de dados concomitantemente à aplicação de questionários estruturados segundo a ISO 10551, aos quais incluíram-se questões acerca do uso de ar-condicionado no local de trabalho e no ambiente doméstico. Dos resultados obtidos, notou-se que o uso frequente de ar-condicionado impacta a percepção térmica dos usuários, e influencia na definição de limites de conforto em espaços abertos, para os índices PET e UTCI avaliados.

  3. Permeabilidade ao ar em Latossolo Vermelho sob diferentes sistemas de manejo

    Directory of Open Access Journals (Sweden)

    Sueli Rodrigues

    2011-02-01

    Full Text Available A permeabilidade ao ar pode ser utilizada para avaliar alterações que ocorrem na estrutura do solo em virtude da adoção de diferentes sistemas de manejo. Este estudo testou a hipótese de que o menor revolvimento do solo sob sistema plantio direto resulta na formação de poros mais contínuos e melhor condição de aeração no solo. O objetivo deste trabalho foi avaliar, por meio da permeabilidade ao ar (Ka, da porosidade de aeração (εa e dos índices de continuidade de poros (K1 e N, a aeração em um Latossolo Vermelho distrófico sob preparo convencional (PC e sistema plantio direto (SPD. Oitenta amostras de solo (2 tratamentos x 2 profundidades x 20 repetições com estrutura indeformada foram coletadas de cada sistema de manejo do solo nas profundidades de 0-0,10 e 0,10-0,20 m em área experimental do Instituto Agronômico do Paraná, no município de Ponta Grossa, Paraná. Depois de saturadas e equilibradas em seis potenciais mátricos (-2, -6, -10, -30, -70 e -100 kPa, determinou-se a permeabilidade ao ar e a porosidade de aeração em cada potencial. Também foram determinados a densidade do solo, a densidade de partícula, o carbono orgânico e a porosidade. A densidade do solo não consistiu em fator limitante, ficando abaixo do limite crítico para solos argilosos nos dois sistemas. No SPD, o maior volume de microporos resultou em maior retenção de água no intervalo de umidade avaliado (-2 a -100 kPa e em maior volume de poros bloqueados para o fluxo de ar (εb, ou seja, redução de Ka. Na profundidade avaliada (00,20 m, os índices de continuidade de poros (K1 e N revelaram que o PC apresentou poros mais contínuos do que o SPD, contradizendo a hipótese testada.

  4. Determinação analítica da performance da irrigação por sulcos abertos e em declive

    Directory of Open Access Journals (Sweden)

    Aristides Fraga Lima Filho

    2015-06-01

    Full Text Available Uma solução analítica foi desenvolvida, para avaliar sulcos abertos e em declive, com base na teoria de Balanço de Volume de Walker e Skogerboe (1987. Essa metodologia é capaz de obter, matematicamente, a performance de um sistema, dispensando a construção de gráficos que definem os parâmetros de avaliação. A solução matemática é baseada no ajuste de equações ao modelo potencial, no cálculo das áreas sob as curvas definidas no ajuste e na intercessão de curvas, obtendo-se, assim, a performance de sistemas de irrigação por sulcos abertos e em declive. Para validação da metodologia, foi realizado um experimento de campo, na Fazenda Experimental da Universidade Federal do Ceará, situada no município de Pentecoste, pertencente ao Centro de Ciências Agrárias. Os dados de campo foram submetidos à análise pelas duas metodologias. Os resultados mostraram que a metodologia analítica pode ser usada para avaliar a irrigação por sulcos abertos e em declive.

  5. Projecto 254 - Produção de suínos ao ar livre : unidade de demonstração Programa AGRO

    OpenAIRE

    Marinho, M.C.; Dias, S.F.; Rodrigues, J.P.V.

    2006-01-01

    A produção de suínos ao ar livre pode contribuir para a preservação e valorização das raças autóctones e dos produtos delas derivados, evitando assim a sua extinção. O projecto, Produção de suínos ao ar livre – Unidade de demonstração, cujo período de execução vai de setembro de 2004 a dezembro de 2006, tem como principal objectivo demonstrar a tecnologia de produção de leitões ao ar livre. Programa AGRO - Projecto 254, Medida 8.1.

  6. The free/open source software movement: resistance or change? = O movimento de software livre/aberto: resistência ou mudança?

    Directory of Open Access Journals (Sweden)

    Georgopoulou, Panayiota

    2009-01-01

    Full Text Available Num momento em que as empresas privadas estão inventando modos de "bloqueio de informação" e em que governos neo-liberais estão impondo sanções severas para aqueles que violam os direitos de propriedade intelectual, o Movimento de Software Liver/Aberto foi contra o neo-liberalismo e a privatização generalizada: o movimento desafia regulações de propriedade em uma área-chave de crescimento das sociedades capitalistas contemporâneas, a saber, a construção e utilização de informações. No final dos anos 1990, o Movimento de Software Livre/Aberto parecia ser uma força desestabilizadora e perturbadora da propriedade intelectual e do neo-liberalismo, ainda como software aberto, ele se transformou em um fenômeno econômico singular, indicando que a comercialização e ganhos financeiros já podem existir sem que se baseie no conceito de propriedade. Isto pode não ser prejudicial para a lógica capitalista, mas alargar as suas perspectivas. Ao negar o regime de propriedade imposto sobre a informação e ao colocar o potencial da "economia de abundância" do novo mundo digital à disposição da boa utilização, o Movimento de Software Livre/Aberto está desistindo de um plano de resistência política ou mostrando o caminho para uma potencial transformação do capitalismo? Talvez as novas condições da política podem ser encontradas no coração da economia e na sua transição em direção a uma "economia de abundância" no mundo digital

  7. O Impacto da Corrupção nas Decisões de Investimento das Firmas Brasileiras de Capital Aberto

    Directory of Open Access Journals (Sweden)

    Aline D. Pellicani

    Full Text Available Esse estudo investiga como a corrupção afeta as decisões de investimento de firmas brasileiras de capital aberto. Os resultados mostram que a corrupção torna a sensibilidade do investimento ao fluxo de caixa fortemente negativa, evidenciando que, neste caso, as firmas tenderiam a adiar ou cancelar investimentos. Esses resultados são encontrados principalmente em firmas do setor de administração de empreendimentos e firmas familiares. Quando a corrupção é considerada, empresas estatais do setor de eletricidade, gás e água apresentam sensibilidade do investimento ao fluxo de caixa cerca de sete vezes superior ao de firmas não-estatais, indicando potenciais problemas de agência.

  8. Dados abertos conectados e gestão do conhecimento: estudos de caso cientométricos em uma universidade brasileira

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    Sandro Rautenberg

    Full Text Available RESUMO Este artigo se baseia na relação de três conceitos: Gestão do Conhecimento, Cientometria e Dados Abertos Conectados. No contexto das universidades, objetiva-se discutir a promoção da Gestão do Conhecimento institucional amparada por Dados Abertos Conectados advindos do domínio da Cientometria. Para tanto, baseando-se nos preceitos da Web Semântica, pontualmente, no processo metodológico Linked Data Lifecycle, duas bases de dados são abertamente mantidas na Web de Dados: a o histórico do Índice Qualis (2005-2015; e b um conjunto de registros de publicações em periódicos extraído da Plataforma Lattes. Como resultado, três estudos de caso reais são desenvolvidos, os quais consumem, relacionam e exploram os dados dessas fontes. Mediante os estudos realizados, conclui-se que as práticas relativas aos Dados Abertos Conectados contribuem na formação de bases de conhecimento institucionais, podendo suportar diversos estudos bibliométricos e cientométricos ou as atividades aderentes à Gestão do Conhecimento universidades brasileiras.

  9. O uso de recursos educativos abertos (rea: benefícios para alunos e professores. O repositório de acesso aberto de Portugal │ Use of open educational resources (oer: benefits for students and teachers. The Portuguese open access repository

    Directory of Open Access Journals (Sweden)

    Maria Teresa Ferreira Costa

    2012-12-01

    Full Text Available Resumo Os Recursos Educativos Abertos (REA têm sido utilizados um pouco por todo o mundo, por Instituições de Ensino Superior, no sentido de abrir o conhecimento a todos que dele necessitam e, muitas vezes, desenvolvendo-se num objectivo de nivelador social. A sua produção assume-se como um procedimento normal por parte dos docentes visando envolver também os alunos, de forma a transformar uma determinada realidade do processo de ensino-aprendizagem numa outra com o objectivo da inclusão. A utilização de materiais pedagógicos digitais livres fornece ao professor a possibilidade de adaptação desses objetos aos mais diversos contextos de aprendizagem conforme os níveis, estilos e necessidades específicas dos alunos. A adopção dos REA, intimamente associada e decorrente do Movimento do Acesso Aberto (AA, no processo de ensino-aprendizagem permite estabelecer uma metodologia diferente, inovadora e tecnologicamente atual, potenciadora do uso das novas tecnologias de informação e comunicação (TIC. Palavras-chave Acesso Aberto, Recursos Educativos Abertos, Processo de Ensino-Aprendizagem, Portugal Abstract Open Educational Resources (OER have been used all over the world by Universities with the purpose of sharing knowledge with those who seek it, and often developing as an objective for social issues. Its production is becoming a common procedure by teachers, in a way to both involve students and to transform a certain reality of the teaching-learning process into a more inclusive one. The use of free digital pedagogical material gives the teacher the possibility of adapting those objects to the many different contexts of the learning process, according to the students’ level, styles and specific needs. The choice for the use of OER, closely associated to the Open Access Movement (OAM, allows establishing an innovative methodology in the teaching-learning process, a technological solution that potentiates the use of the new

  10. Sistema de aquisição de dados para equipamento de medida da permeabilidade intrínseca do solo ao ar

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    Luciano Roberto da Silveira

    2011-04-01

    Full Text Available A permeabilidade intrínseca - ou simplesmente permeabilidade do solo ao ar - é uma propriedade importante para a identificação de alterações no espaço poroso do solo causadas pelas práticas de manejo, na estimativa de propriedades do solo mais difíceis e onerosas e na composição de modelos de fluxo de fluidos em solos agrícolas e em solos contaminados. O objetivo do presente estudo foi construir um sistema de aquisição de dados (módulo eletrônico e programa computacional para a medida da permeabilidade do solo ao ar em laboratório, utilizando-se materiais disponíveis no local e ferramentas computacionais de acesso livre. O sistema de aquisição de dados mostrou-se bastante preciso na determinação da permeabilidade do solo ao ar, com intervalo de confiança de 9,42 ± 0,085 μm² (95 %, para uma amostra-padrão constituída de partículas com diâmetro de 0,106 a 0,250 mm da fração areia de um Latossolo Vermelho-Amarelo textura média. A estimativa da permeabilidade do solo ao ar, considerando a viscosidade dinâmica do ar em função da temperatura, foi significativamente maior que a estimativa com valor fixo de viscosidade dinâmica em aproximadamente 20 ºC. A medição realizada em uma amostra de solo com estrutura indeformada de um Latossolo Vermelho foi tão precisa quanto à da amostra-padrão, e a estimativa da massa de água removida da amostra foi de 3,27 mg.

  11. Relação entre baixo peso ao nascer e a poluição do ar no Município de São Paulo

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    Andréa Medeiros

    2005-12-01

    Full Text Available OBJETIVO: A poluição do ar tem sido investigada como possível determinante do baixo peso ao nascer. O objetivo do estudo foi verificar o efeito da poluição do ar sobre o peso ao nascer. MÉTODOS: Foram analisados todos os partos de mães residentes no Município de São Paulo, nos anos de 1998 a 2000. Estimaram-se as prevalências de baixo peso ao nascer conforme características do recém-nascido, da mãe e do parto. Apenas os distritos mais centrais de São Paulo foram incluídos, totalizando uma amostra de 311.735 nascimentos. Para avaliação do efeito da poluição do ar foram excluídos os prematuros, gemelares e analisados somente os nascimentos das áreas mais centrais da cidade. Os elementos poluentes analisados foram ozônio (O3, dióxido de enxofre (SO2, dióxido de nitrogênio (NO2, partículas em suspensão (PM10 e monóxido de carbono (CO. O efeito da exposição materna à poluição do ar no peso ao nascer foi avaliado por meio de regressão linear e logística. RESULTADOS: Do total analisado, 4,6% dos recém-nascidos apresentaram menos de 2.500 g ao nascer. A exposição materna ao CO, PM10 e NO2 durante o primeiro trimestre de gestação mostrou associação estatisticamente significante com a diminuição no peso do recém-nascido. CONCLUSÕES: Os resultados reforçam que a exposição materna à poluição do ar no primeiro trimestre de gestação pode contribuir para o menor ganho de peso do feto.

  12. Estudo de conforto em espaços abertos em região de clima temperado: o caso de Glasgow, Reino Unido

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    Eduardo Leite Krüger

    Full Text Available O estudo da sensação de conforto térmico em espaços abertos deve ser entendido como primordial para o planejamento climaticamente adequado de áreas urbanas. Através do aumento da atratividade das àreas abertas e do incentivo às atividades ao ar livre, o planejamento urbano norteado do pelas preferências térmicas da população torna-se um agente facilitador do uso desses espaços. O presente trabalho analisa a sensação térmica de moradores de Glasgow, Reino Unido, localizada em região temperada, comparando respostas obtidas por meio de entrevistas estruturadas a índices utilizados pela meteorologia (Wind Chill e THSW e em estudos de conforto (PET e PMV. Os dados foram coletados em 19 campanhas de monitoramento, no período do inverno ao verão de 2011. Para a coleta de dados, foi utilizada uma estação Davis Vantage Pro2, contendo sensores de temperatura e umidade relativa, anemômetro e piranômetro. Foi confeccionado um termômetro de globo, utilizado para obtenção da temperatura radiante média (TRM, equipado com um data logger (Tinytag-TGP-4500. Os resultados indicam que os índices THSW e PET foram os que mais se aproximaram da resposta térmica dos entrevistados, podendo ser aplicados no entendimento das condições do clima na cidade e entorno de Glasgow.

  13. Espectroscopia de candidatos a remanescentes de aglomerados abertos

    Science.gov (United States)

    Pavani, D. B.; Bica, E.; Ahumada, A. V.; Clariá, J. J.

    2003-08-01

    A pesquisa sobre remanescentes de aglomerados abertos tem despertado grande interesse. Seguindo esta tendência encontramos estudos teóricos e observacionais. Os primeiros baseiam-se em simulações numéricas buscando determinar fração de binárias e distâncias galatocêntricas, tempo de vida e conteúdo estelar. Estes estão relacionados à função inicial de massa e densidade de estrelas, ou seja, se ricos ou pobremente povoados, compactos ou esparsos. No caso observacional procuram-se identificar os remanescentes considerando-se que trazem estas assinaturas de seus percursores. No presente estudo empregamos espectroscopia para analisar oito concentrações pobremente povoadas, previamente classificadas como aglomerados abertos, sendo sete compactas e uma esparsa. As observações foram obtidas através do telescópio de 2,15 m do CASLEO em San Juan, Argentina, em turnos entre 2001 e 2003. Utilizamos uma câmara CCD contendo um chip Tektronics de 1024X1024 pixeis aliado a um espectrógrafo REOSC. O domínio espectral vai de 3700 a 7000 Å. As reduções foram realizadas no Observatório Astronômico de Córdoba (Argentina) usando pacotes IRAF padrões. Determinamos idades, avermelhamentos e tipos espectrais através de comparações com biblioteca de estrelas e de aglomerados. Em alguns casos nossos espectros estavam dominados por estrelas individuais às quais determinamos seus tipos espectrais. Aos oito objetos adicionamos mais cinco da literatura recente analisados via espectro ou diagrama cor-magnitude. O histograma resultante contém idades típicas entre 0.5 e 3 Ganos. Considerando que predominantemente estes objetos encontram-se na vizinhança solar e, portanto, não cruzaram muitas vezes o plano Galático esperamos que a diferença no tempo necessário para dissolução destes prováveis remanescentes seja em função de diferentes massas iniciais.

  14. Abordagens, estratégias e ferramentas para o acesso aberto via periódicos e repositórios institucionais em instituições acadêmicas brasileiras | Approaches, strategies and tools for open access through journals and institutional repositories in Brazilian

    Directory of Open Access Journals (Sweden)

    Sely Costa

    2008-09-01

    Full Text Available Resumo Este ensaio tem por objetivo discutir, de modo sucinto, o movimento do acesso aberto nos dias atuais, procurando-se identificar a diferença entre acesso aberto à literatura científica e acesso aberto ao conhecimento científico. A abordagem do acesso aberto à literatura relaciona-se com o processo de comunicação, enquanto o acesso aberto ao conhecimento científico, com a gestão do conhecimento. Recorre-se à literatura e à experiência pessoal no intuito de identificar e relatar estratégias e ferramentas que têm sido utilizadas em diferentes países e no próprio Brasil. A discussão fundamenta-se em três tópicos considerados basilares para o estudo e a prática com periódicos eletrônicos e repositórios de acesso aberto, que são: as diferenças disciplinares, o sistema de comunicação científica e os modelos de gestão do conhecimento. Parte-se do pressuposto de que as diferenças disciplinares devem nortear as ações e decisões a respeito da criação e manutenção de revistas e repositórios. As primeiras, como veículos efetivos de comunicação científica. Os últimos, como, ferramentas eficientes de gestão do conhecimento. Palavras-chave acesso aberto à literatura científica; acesso aberto ao conhecimento científico; periódicos científicos eletrônicos de acesso aberto; repositórios institucionais; diferenças disciplinares; modelo de comunicação científica; modelo de gestão do conhecimento científico. Abstract This essay aims at briefly discussing the open access movement today, trying to identify the difference between open access to scientific literature and open access to scientific knowledge. Open access to scientific literature is related to the scholarly communication process approach, while open access to scientific knowledge concerns the knowledge management approach. Both the literature and personal experience are used as the basis for discussion, attempting to identify and report

  15. MICOBIOTA ASSOCIADA À MADEIRA SERRADA DE Eucalyptus grandis HILL EX MAIDEN DURANTE A SECAGEM AO AR LIVRE

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    Paulo Fernando Trugilho

    2006-02-01

    Full Text Available O objetivo principal deste trabalho foi o de acompanhar a secagem ao ar livre da madeira serrada de Eucalyptus grandis conduzida na região de Lavras, MG e identificar a micobiota associada à madeira em diversas fases da secagem. As tábuas foram cortadas de oito toras de 3,0 m de comprimento, oriundas de três árvores, com 27 anos de idade, plantadas em área experimental da UFLA. Dos resultados, pôde-se concluir que a secagem da madeira de Eucalyptus grandis ao ar livre, iniciada em janeiro, consumiu 158 dias até atingir umidade próxima a 12,5%. A curva de secagem foi representada por uma equação logarítmica com coeficiente de determinação (R2 igual a 98,3%. Os fungos causadores de bolores superficiais e de manchas tiveram maior ocorrência no início da secagem. As mais altas freqüências de fungos, verificadas no início da secagem, foram observadas para Penicillium spp. e Pestalotiopsis sp. O fungo Lentinus lepideus ocorreu com maior freqüência no final da secagem.

  16. DESENVOLVIMENTO DE UM PROGRAMA ABERTO DE ENSINO DE SISTEMAS DE CONTROLE

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    Ricardo Andrade Cava

    2010-01-01

    Full Text Available Este artigo apresenta os resultados produzidos no desenvolvimento de um Programa Aberto de Ensino de Sistemas de Controle (PAESC a ser utilizado como ferramenta auxiliar nas atividades de ensino da disciplina de Sistemas de Controle. Essa disciplina é parte integrante de vários currículos em cursos de engenharia e possui uma característica multidisciplinar, envolvendo, dentre outros, conteúdos de Cálculo, Física, Circuitos Elétricos, Mecanismos, dificultando o aprendizado dos alunos. Com o objetivo primordial de suprir essa dificuldade, o Programa Aberto de Ensino de Sistemas de Controle está sendo desenvolvido no sentido de proporcionar uma ferramenta tecnológica, disponível pela Web, para auxiliar o aprendizado dos futuros engenheiros. Para tanto, apresenta gráficos, animações e permite a interação. A ferramenta está sendo construída em linguagem Java, e os códigos produzidos são abertos, de modo a permitir que possam ser enviadas contribuições às simulações desenvolvidas.

  17. Produção e tolerância ao pendoamento de alface-romana em diferentes ambientes

    Directory of Open Access Journals (Sweden)

    Cárita Rodrigues de Aquino

    2014-08-01

    Full Text Available O experimento foi conduzido na área experimental da Universidade do Estado de Mato Grosso, localizada no município de Cáceres-MT, no período de maio a agosto de 2011, com o objetivo de avaliar a influência de diferentes ambientes e espaçamentos na produção e tolerância ao pendoamento de alface-romana cultivar Sophia. O delineamento experimental foi em blocos casualizados, arranjados em esquema fatorial 2 x 5, composto por dois espaçamentos (30 x 30 cm e 25 x 25 cm e cinco ambientes de cultivo (tela de sombreamento 30 e 50% , tela termorrefletora de 30 e 50% e ambiente aberto, perfazendo 10 tratamentos com quatro repetições cada. As parcelas experimentais foram constituídas por quatro linhas, com cinco plantas cada, totalizando 20 plantas por parcela. Consideraram-se como área útil para avaliação da produção as seis plantas centrais. As parcelas em que foi utilizado o espaçamento 30 x 30 cm apresentavam 1,8 m² cada, e as com o espaçamento 25 x 25 cm, 1,5 m² cada. As mudas foram transplantadas com 26 dias e a colheita realizada aos 46 dias após o transplantio. Observou-se que o espaçamento de 25 x 25 cm entre plantas e o ambiente aberto proporcionaram maior produtividade da alface-romana. Porém, o tempo para pendoamento das plantas no ambiente aberto foi menor que nos ambientes com as telas de sombreamento ou termorrefletora.

  18. Perfil dos idosos usuários das academias ao ar livre para a terceira idade

    Directory of Open Access Journals (Sweden)

    Wesley Lessa Pinheiro

    2017-03-01

    Full Text Available Objetivo: Descrever o perfil dos idosos usuários das academias ao ar livre para a terceira idade de Fortaleza,Ceará. Métodos: Estudo transversal, envolvendo uma amostra de 374 idosos com idade maior ou igual a 60 anos, realizado entre os meses de outubro de 2015 e abril de 2016, nas academias ao ar livre para a terceira idade em Fortaleza, Ceará. Aplicou-se um questionário contendo questões sobre dados sociodemográficos, condições de saúde e hábitos de vida autorrelatados, e sobre a utilização dos equipamentos. Mensurou-se o peso e a altura para a obtenção do índice de massa corporal (IMC. Resultados: A maioria dos entrevistados era mulher (56,7%, n=212 e com faixa etária entre 60 e 69 anos (66,8%, n=250. As principais condições de saúde autorrelatadas foram hipertensão (40,9%, n=153, colesterol alto (32,4%, n=121 e osteoartrite (26,2%, n=98. Entre os hábitos de vida, o consumo de bebida alcoólica (31,6%, n=118 foi o mais relatado. Verificou-se que 42,8% (n=160 encontrava-se com excesso de peso. A maioria utilizava os equipamentos há mais de um ano (68,2%, n=255, até 30 minutos por dia (49,5%, n=185, cinco ou mais dias durante a semana (51%, n=191, tendo em grande parte percebido melhora na saúde (93,6%, n=350. Conclusão: Os idosos apresentaram um perfil jovem e ativo, cujas condições de saúde de maior prevalência podem ser facilmente manejadas com a prática de atividade física, e apresentam características semelhantes independentemente da situação econômica em que se encontram inseridos.

  19. Utilização de código aberto de dinâmica de fluidos computacional para estudo de placas de orifício

    OpenAIRE

    Thiago Teixeira Kunz

    2014-01-01

    Este trabalho apresenta simulações numéricas de escoamento de fluidos através de placas de orifício, elementos primários de medição de vazão, em comparação aos resultados esperados por normas internacionais. O coeficiente de descarga usado para a determinação da vazão de um escoamento em uma tubulação foi obtido numericamente através da aplicação do modelo de turbulência de baixo Reynolds proposto por Launder-Sharma, resolvido através de um código aberto de Dinâmica de Fluidos Computacional. ...

  20. Julgamento de colinearidade e percepção de distância exocêntrica em campo aberto

    Directory of Open Access Journals (Sweden)

    Javier Enrique Santillán

    2011-01-01

    Full Text Available O propósito foi investigar experimentalmente o desempenho dos observadores numa original tarefa de julgamento de colinearidade em campo aberto (dimensões 20 x 30 m. Participaram do experimento 30 observadores. Os estímulos foram estacas verticais de alturas variáveis, quatro fixos e quatro móveis. A tarefa consistiu em ajustar os dois estímulos móveis (mediante controle à distância para que ficassem colineares aos dos estímulos fixos nos extremos de cada diagonal. Foi realizada uma análise de variância (ANOVA fatorial sobre os erros de colinearidade, revelando somente efeito significativo para o fator ‘Estímulo Móvel’ (F(3,473=69,86 p<0,001 notando-se uma sistemática na distribuição dos erros. As pequenas variações na distância exocêntrica percebida (com erros constantes dez vezes menores que os encontrados ao avaliar as distâncias egocêntricas e a relação dos erros cometidos com as distâncias egocêntricas indicariam que o marco de referência eliciado por esta tarefa de colinearidade, embora possa estar baseado nos indícios exocêntricos, é escalado por um fator egocêntrico.

  1. Influência do DNA mitocondrial no glaucoma primário de ângulo aberto sob a visão da cienciometria

    Directory of Open Access Journals (Sweden)

    Leonardo Mariano Reis

    2013-10-01

    Full Text Available OBJETIVO: O glaucoma primário de ângulo aberto é uma doença degenerativa do nervo óptico que se encontra entre as principais causas de cegueira no mundo. Aspectos familiares já foram implicados como fatores importantes e comprovados em inúmeros estudos. Nesse artigo, apresentamos uma revisão sistemática dos trabalhos sobre glaucoma primário de ângulo aberto e DNA mitocondrial e fazemos uma análise estatística à luz dos conceitos da cienciometria. MÉTODOS: A pesquisa bibliográfica de trabalhos envolvendo DNA mitocondrial e glaucoma primário de ângulo aberto foi realizada por meio da base de dados do sítio Scopus. Foi feito o levantamento a partir das palavras-chaves "Mitochondrial DNA" e "Glaucoma" em todos os campos para publicações no período compreendido de 1992 até agosto de 2012. Finalmente, foi realizada a estatística e cienciometria com os principais dados: autores que publicaram sobre o assunto DNA mitocondrial e glaucoma; revistas e outras publicações que tiveram trabalhos relacionados com o tema; Centros de Pesquisa e Universidades que mais publicaram e países onde foram realizados os estudos sobre DNA mitocondrial e glaucoma. RESULTADOS: Identificamos que esses estudos têm aumentado sobremaneira ao longo dos últimos anos, mas ainda se encontram confinados, na maior parte, a alguns centros de pesquisa e concentrados em seletos grupos de autores na área da oftalmologia em países desenvolvidos. No Brasil, ainda não temos pesquisas publicadas sobre o assunto até o momento. CONCLUSÃO: Esses estudos são de fundamental importância para a elucidação das causas genéticas do glaucoma e para o desenvolvimento de novas terapias que não visem tão somente a diminuição da pressão intraocular.

  2. Grau de exposição a praguicidas organoclorados em moradores de aterro a céu aberto

    Directory of Open Access Journals (Sweden)

    Eladio Santos Filho

    2003-08-01

    Full Text Available OBJETIVO: Estimar o grau de exposição interna aos praguicidas organoclorados (POP dos moradores de um atêrro a céu aberto. MÉTODOS: Estudo observacional, de aferição simultânea e controlado, cujo fator de estudo foi residir em área contaminada por POP e o efeito foi a concentração sanguínea dessas substâncias. A população de estudo foi de 238 pessoas residentes em um aterro a céu aberto (Pilões, no município de Cubatão, SP; e a população de controle ficou dimensionada em 258 pessoas, também residentes no mesmo município (Cota 200. Foram analisados os praguicidas HCB, p-p'DDT, p-p'DDE, p-p'DDD, o-p'DDT, a HCH; b HCH; g HCH; Aldrin; Dieldrin; Endrin; Heptaclor; Heptaclor-epoxi e Mirex. RESULTADOS: Os teores médios sangüíneos de HCB em Pilões foram de 4,66 µg/L, 155 vezes maior que a média na Cota 200 (0,03 µg/L. Em Pilões, os teores médios de DDT total foram de 3,71 µg/L, duas vezes maior do que na Cota 200 (1,85 µg/L e o HCH total apresentou concentrações sangüíneas seis vezes maiores em Pilões, 0,84 µg/L, contra 0,13 µg/L. CONCLUSÕES: Evidenciou-se associação positiva entre residir em Pilões e apresentar teores sangüíneos de POP, com risco muitas vezes maior quando comparado a localidades sem a presença desses contaminantes.

  3. Grau de exposição a praguicidas organoclorados em moradores de aterro a céu aberto

    Directory of Open Access Journals (Sweden)

    Santos Filho Eladio

    2003-01-01

    Full Text Available OBJETIVO: Estimar o grau de exposição interna aos praguicidas organoclorados (POP dos moradores de um atêrro a céu aberto. MÉTODOS: Estudo observacional, de aferição simultânea e controlado, cujo fator de estudo foi residir em área contaminada por POP e o efeito foi a concentração sanguínea dessas substâncias. A população de estudo foi de 238 pessoas residentes em um aterro a céu aberto (Pilões, no município de Cubatão, SP; e a população de controle ficou dimensionada em 258 pessoas, também residentes no mesmo município (Cota 200. Foram analisados os praguicidas HCB, p-p'DDT, p-p'DDE, p-p'DDD, o-p'DDT, a HCH; b HCH; g HCH; Aldrin; Dieldrin; Endrin; Heptaclor; Heptaclor-epoxi e Mirex. RESULTADOS: Os teores médios sangüíneos de HCB em Pilões foram de 4,66 µg/L, 155 vezes maior que a média na Cota 200 (0,03 µg/L. Em Pilões, os teores médios de DDT total foram de 3,71 µg/L, duas vezes maior do que na Cota 200 (1,85 µg/L e o HCH total apresentou concentrações sangüíneas seis vezes maiores em Pilões, 0,84 µg/L, contra 0,13 µg/L. CONCLUSÕES: Evidenciou-se associação positiva entre residir em Pilões e apresentar teores sangüíneos de POP, com risco muitas vezes maior quando comparado a localidades sem a presença desses contaminantes.

  4. DA PSICODINÂMICA DO TRABALHO AO DIREITO FUNDAMENTAL AO CONTEÚDO DO PRÓPRIO TRABALHO E AO MEIO AMBIENTE ORGANIZACIONAL SAUDÁVEL

    Directory of Open Access Journals (Sweden)

    Leonardo Vieira Wandelli

    2015-10-01

    Full Text Available O presente artigo procura traçar alguns elementos que pretendem articular como, a partir do discurso jurídico, podem ser significados os aportes sobre saúde e trabalho, especialmente aqueles trazidos pela abordagem da Psicodinâmica do Trabalho. Um caminho, assim, que vai dos estudos sobre sujeito, trabalho e saúde até o Direito Constitucional, que afirma como seu fundamento a dignidade humana, indissociável da centralidade antropológica do trabalho; um vínculo expressado pelo direito fundamental ao trabalho que, aqui, se propõe reconstruir a partir do desvelamento de um direito fundamental ao conteúdo do próprio trabalho, articulado ao conceito de meio ambiente organizacional do trabalho. 

  5. Participação Popular no Contexto das iniciativas de Governo Aberto: revisão sistemática da literatura

    Directory of Open Access Journals (Sweden)

    Cristiane Sinimbu Sanchez

    2017-12-01

    Full Text Available As iniciativas de Governo Aberto (GA preconizam a transparência, a colaboração e a inovação, o controle social e a participação como formas de combate à corrupção e aprimoramento da gestão democrática. Este estudo buscou explorar os elementos que caracterizam a participação popular no contexto das iniciativas de Governo Aberto, derivando-se da aplicação de alguns protocolos de revisão sistemática da literatura, estruturado com base em estratégia de busca nas bases de dados: Business Source Complete, Science Direct e Web of Science – Coleção Principal. Aplicaram-se critérios de inclusão/exclusão de documentos, resultando em 64 documentos para análise. Os resultados indicam que a participação, no contexto de GA, compõe-se de alguns elementos, a saber: espaços, ferramentas, tecnologias de informação e comunicação. A participação se dá, por vezes, de forma institucionalizada, sustentada por entidades coletivas que representam a sociedade civil organizada. Quanto à participação dos cidadãos na elaboração destas políticas, as iniciativas de GA se encontram em estágio de implementação e reformulação de políticas que garantam tanto o acesso aos dados abertos governamentais, assim como os espaços de representação da sociedade. Aponta-se, ainda, que existem condicionantes para a participação – barreiras e desafios – que estão relacionadas à assimetria de informação, falta de experiência no uso das ferramentas, entre outros. Destaca-se que a sistematização destes elementos pode contribuir para a melhoria de políticas de inclusão da sociedade na elaboração e acompanhamento de políticas públicas de interesse dos cidadãos. Considera-se que a apresentação e discussão destes elementos possa contribuir, futuramente, para a criação um quadro conceitual na temática.

  6. Indicadores de Liquidez e o Fluxo de Caixa Operacional: Um Estudo nas Empresas Brasileiras de Capital Aberto

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    Ercilio Zanolla

    2014-09-01

    Full Text Available Esta pesquisa teve o objetivo de estudar a relação da liquidez mensurada pelo capital circulante líquido (CCL e pela necessidade de capital de giro (NCG, com o fluxo de caixa operacional (FCO. A liquidez, historicamente, é determinada pela liquidez corrente (LC que, também, pode ser mensurada pela diferença entre o ativo circulante (AC e passivo circulante (PC, definida como CCL. Ao final da década de 1970, Fleuriet, criou um modelo de avaliação de liquidez, similar ao CCL, que sugere a reclassificação do AC e PC em financeiro e operacional para extrair o valor da NCG determinado pela diferença entre os investimentos e financiamentos operacionais de curto prazo. No entanto, o FCO como resultado de entradas e saídas de recursos operacionais, a priori, evidencia melhor a liquidez. A pesquisa foi realizada em 166 empresas brasileiras de capital aberto no período de 2008 ao segundo trimestre de 2012. Para tratamento e análise dos dados, utilizou-se o modelo de dados em painel de efeitos fixos. Os resultados indicam que a métrica de liquidez NCG não é significante para explicar o FCO; o CCL; embora estatisticamente significante, apresenta pequena contribuição adicional no coeficiente de determinação ajustado, R2. Assim, pode-se inferir que os achados da pesquisa confirmam a teoria e expõem que a liquidez mensurada pelo CCL e a NCG não representa fidedignamente os ativos realizados em caixa a exemplo dos mensurados pelo FCO que efetivamente representa as entradas e saídas de recursos operacionais. Esta constatação confirmada nas evidências empíricas da variável que representa a variação de ativos e passivos operacionais (vap. Assim, o estudo remete há discussões e mudanças na estrutura conceitual e de mensuração do CCL e NCG.

  7. GOVERNANÇA CORPORATIVA E CUSTO DE CAPITAL DE TERCEIROS: EVIDÊNCIAS ENTRE EMPRESAS BRASILEIRAS DE CAPITAL ABERTO

    Directory of Open Access Journals (Sweden)

    Camila Veneo Campos Fonseca

    Full Text Available RESUMO O reduzido acesso ao capital de terceiros, especialmente os de mais longo prazo, é um dos principais problemas do ambiente corporativo brasileiro. Conflitos de agência e existência de informação assimétrica nas transações efetivadas no mercado financeiro resultam no racionamento do crédito e no encarecimento do custo de capital. A adoção de melhores práticas de governança corporativa pelas empresas, ao implicar redução do custo de capital, amplia a captação de recursos para o investimento, mitigando o problema do financiamento empresarial. O objetivo deste estudo é avaliar a relação entre a adoção de melhores práticas de governança corporativa e o custo do capital de terceiros das empresas brasileiras não financeiras de capital aberto no período 2010-2014. De forma a atingir tal objetivo, foi utilizado um modelo de dados de painel com 230 companhias, sendo a estimação realizada pelo Método dos Momentos Generalizado Sistêmico (GMM-Sis. Os resultados apontaram que a adoção de melhores níveis de governança corporativa reduziu o custo do capital de terceiros das companhias presentes na amostra. Além disso, verificou-se que as variáveis custo de capital de terceiros do ano anterior, lucratividade e nível de emissão de ações preferenciais exerceram uma influência estatisticamente significativa sobre o custo contemporâneo da dívida.

  8. Materiais de cobertura e suas associações a forros e materiais isolantes no ambiente térmico de protótipos abertos e fechados com vistas a produção de frangos de corte em clima quente

    OpenAIRE

    Carvalho, Humberto Garcia de

    2013-01-01

    Em razão de enormes avanços tecnológicos do setor produtivo, o Brasil passou a ocupar o primeiro lugar mundial no ranking de países exportadores de carne de frango. Contudo, em razão da tipologia, materiais e concepção arquitetônica típica para as condições de clima tropical e subtropical, os aviários abertos brasileiros apresentam fragilidade nos sistemas construtivos devidos ao baixo amortecimento térmico dos envoltórios construtivos, especialmente nas coberturas, gerando condições de estre...

  9. Gerenciamento de resultados e ambiente institucional : um estudo da América Latina

    OpenAIRE

    Guimarães, Daniel Monfort de Alencastro

    2011-01-01

    Nesta dissertação analisamos se o ambiente institucional relacionado ao nível de proteção dos investidores dos países da América Latina contribuiu para uma redução na prática de gerenciamento de resultados das empresas. Utilizamos quatro modelos para detectar a prática de gerenciamento de resultados (Jones Model, Modified Jones Model, Modified Jones Model with ROA e o Kang & Sivaramakrishna Model). A nossa amostra é formada pelas empresas de capital aberto e listada em bolsa nos países da Ar...

  10. Cultivo de Spirulina maxima ao ar livre - I. Inverno

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    Rogério Lacaz Ruiz

    1990-12-01

    e noturno indicaram que o melhor período de produção de biomassa durante o dia foi das 8 - 13 h e a produtividade atingiu valor máximo de 8,08 g/metro quadrado/dia. Durante todo o experimento foi necessário adicionar água ao sistema, devido à ausência de chuvas; e o total acrescentado equivaleu a 72,14 mm de chuva.

  11. RECURSO AO LEGISLADOR: CONSIDERAÇÕES EM TORNO DO CONTROLE LEGISLATIVO AO PODER JUDICIÁRIO (UM EPITÁFIO À PEC Nº33)

    OpenAIRE

    Dettmam, Deborah; Matos, Nelson Juliano Cardoso

    2017-01-01

    Este artigo discute se o recurso ao povo ou ao legislador, como instrumento de resolução dos conflitos entre os poderes, viola a separação de poderes e a independência do poder judiciário ou se, antes disso, dá fiel execução à separação de poderes. Para alcançar esse objetivo, esse artigo investiga se existe relação entre o recurso ao legislador e os regimes autoritários; se a Constituição Federal de 1988 proíbe outro guardião constitucional, que não o Supremo Tribunal Federal, e quais as con...

  12. Ar-Ar_Redux: rigorous error propagation of 40Ar/39Ar data, including covariances

    Science.gov (United States)

    Vermeesch, P.

    2015-12-01

    Rigorous data reduction and error propagation algorithms are needed to realise Earthtime's objective to improve the interlaboratory accuracy of 40Ar/39Ar dating to better than 1% and thereby facilitate the comparison and combination of the K-Ar and U-Pb chronometers. Ar-Ar_Redux is a new data reduction protocol and software program for 40Ar/39Ar geochronology which takes into account two previously underappreciated aspects of the method: 1. 40Ar/39Ar measurements are compositional dataIn its simplest form, the 40Ar/39Ar age equation can be written as: t = log(1+J [40Ar/39Ar-298.5636Ar/39Ar])/λ = log(1 + JR)/λ Where λ is the 40K decay constant and J is the irradiation parameter. The age t does not depend on the absolute abundances of the three argon isotopes but only on their relative ratios. Thus, the 36Ar, 39Ar and 40Ar abundances can be normalised to unity and plotted on a ternary diagram or 'simplex'. Argon isotopic data are therefore subject to the peculiar mathematics of 'compositional data', sensu Aitchison (1986, The Statistical Analysis of Compositional Data, Chapman & Hall). 2. Correlated errors are pervasive throughout the 40Ar/39Ar methodCurrent data reduction protocols for 40Ar/39Ar geochronology propagate the age uncertainty as follows: σ2(t) = [J2 σ2(R) + R2 σ2(J)] / [λ2 (1 + R J)], which implies zero covariance between R and J. In reality, however, significant error correlations are found in every step of the 40Ar/39Ar data acquisition and processing, in both single and multi collector instruments, during blank, interference and decay corrections, age calculation etc. Ar-Ar_Redux revisits every aspect of the 40Ar/39Ar method by casting the raw mass spectrometer data into a contingency table of logratios, which automatically keeps track of all covariances in a compositional context. Application of the method to real data reveals strong correlations (r2 of up to 0.9) between age measurements within a single irradiation batch. Propertly taking

  13. Medidas socioeducativas em meio aberto em Guaíba: entre pressupostos e significados

    OpenAIRE

    Jacques, Luciana Gomes de Lima

    2015-01-01

    No presente estudo, do tipo descritivo e exploratório, de natureza qualitativa, fundamentado no método dialético-crítico, discorre-se sobre os aspectos de proximidade e de distanciamento entre os pressupostos da socioeducação no Sistema Único de Assistência Social (SUAS) e no Sistema Nacional Socioeducativo (SINASE), e analisam-se os significados atribuídos às Medidas Socioeducativas em Meio Aberto (MSE-MA) pelos sujeitos que a protagonizam e/ou que participaram de seu processo de municipaliz...

  14. 40Ar/39Ar geochronology at the Instituto de Geociências, USP: instrumentation, analytical procedures, and calibration

    Directory of Open Access Journals (Sweden)

    PAULO M. VASCONCELOS

    2002-06-01

    Full Text Available Laser heating 40Ar/39Ar geochronology provides high analytical precision and accuracy, mum-scale spatial resolution, and statistically significant data sets for the study of geological and planetary processes. A newly commissioned 40Ar/39Ar laboratory at CPGeo/USP, São Paulo, Brazil, equips the Brazilian scientific community with a new powerful tool applicable to the study of geological and cosmochemical processes. Detailed information about laboratory layout, environmental conditions, and instrumentation provides the necessary parameters for the evaluation of the CPGeo/USP 40Ar/39Ar suitability to a diverse range of applications. Details about analytical procedures, including mineral separation, irradiation at the IPEN/CNEN reactor at USP, and mass spectrometric analysis enable potential researchers to design the necessary sampling and sample preparation program suitable to the objectives of their study. Finally, the results of calibration tests using Ca and K salts and glasses, international mineral standards, and in-house mineral standards show that the accuracy and precision obtained at the 40Ar/39Ar laboratory at CPGeo/USP are comparable to results obtained in the most respected laboratories internationally. The extensive calibration and standardization procedures undertaken ensure that the results of analytical studies carried out in our laboratories will gain immediate international credibility, enabling Brazilian students and scientists to conduct forefront research in earth and planetary sciences.A geocronologia de 40Ar/39Ar por aquecimento a laser permite alta precisão e acurácia analítica, tem resolução espacial em escala micrométrica, e fornece um número de dados estatisticamente significantes para o estudo de processos geológicos e planetários. Um recém construído laboratório de 40Ar/39Ar no CPGeo/USP, São Paulo, Brazil, mune a sociedade científica brasileira com uma técnica eficaz aplicável aos estudos geol

  15. Biomassa microbiana em amostras de solos secadas ao ar e reumedecidas Microbial biomass in air dried and rewetted soil samples

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    Antônio Samarão Gonçalves

    2002-05-01

    Full Text Available O objetivo do trabalho foi avaliar a viabilidade do condicionamento de amostras como terra fina secada ao ar (TFSA por curto período, para a determinação do carbono da biomassa microbiana (BMS-C, pelo método da fumigaçãoextração, e verificar a respiração microbiana basal (RB do solo. O condicionamento como TFSA, procedendo-se à fumigação para a análise da BMS-C imediatamente ou 24 horas após o reumedecimento, proporcionou valores de BMS-C para os solos Podzólicos, Latossolo Vermelho-Amarelo álico e Orgânico, semelhantes aos valores dos seus controles. Os solos Glei Pouco Húmico e Vertissolo apresentaram valores de BMS-C similares aos do controle a partir de 24 horas de incubação; o solo Planossolo arenoso apresentou valores similares aos do controle com 72 horas, e a Rendizina, com 168 horas de incubação. Na maioria dos solos, a RB determinada na TFSA apresentou valores maiores do que os do tratamento-controle, quando avaliada imediatamente ou 24 horas após o reumedecimento a 60% da capacidade máxima de retenção de água, seguida de queda e manutenção em níveis semelhantes ao do controle nos períodos subseqüentes. O précondicionamento, de curta duração, como TFSA, é promissor para a determinação da BMS-C, quando níveis e períodos adequados de reumedecimento são adotados.The objective of this work was to evaluate the utilization of short term air dried soil samples in a determination of soil microbial biomass (SMB-C, by a fumigationextraction method, and soil microbial basal respiration (BR. Zero time or 24 hours rewetting incubation period before fumigation procedure gave values of SMB-C similar to those of the control for the Podzolic soils, Allic RedYellow Latosol and Organic soil. Low Humic Gley and Vertisol soils gave values of SMB-C similar to those of the control for periods of incubation equal or higher than 24 hours. Planosol (sandy soil and Rendzina soils gave values of SMB-C similar to the

  16. Sensibilidade da rosa 'Osiana' ao etileno

    Directory of Open Access Journals (Sweden)

    Delaine Cristina Cordeiro

    2011-01-01

    Full Text Available Os objetivos deste trabalho foram determinar a sensibilidade e as respostas da rosa cultivar Osiana (Rosa × hybrida à presença de etileno ao longo da vida pós-colheita. Para determinar a sensibilidade da flor ao etileno, hastes foram cortadas e colocadas em câmaras herméticas e em seguida tratadas por 24 horas com diferentes concentrações de etileno variando de 0,0; 0,1; 1,0; 10; 100 e 1000 µL L-1do ar no interior da câmara. A rosa teve a vida pós-colheita reduzida pelo etileno, quando exposta a concentração igual ou superior a 10 µL L-1 de etileno. As flores tratadas com no mínimo de 10 µL L-1de etileno desenvolveram necrose, murcha e abscisão prematura das pétalas ainda túrgidas. As concentrações de 0,1 e 1,0 µL L-1de etileno estimularam a abertura do botão floral durante o período de 24 horas de exposição ao etileno, sem no entanto, reduzir a vida pós-colheita. A rosa 'Osiana' pode ser classificada como uma cultivar sensível ao etileno e a concentração influência os processos estimulados.

  17. Resistência ao pendoamento de genótipos de alface em ambientes de cultivo

    Directory of Open Access Journals (Sweden)

    Andrieli Oliveira da Luz

    2010-12-01

    Full Text Available Com o objetivo de avaliar a resistência ao pendoamento de cultivares comerciais de alface tipo crespa em ambientes, no experimento conduzido na área experimental pertencente à UNEMAT de Cáceres-MT foram avaliados 35 tratamentos, utilizando de-lineamento experimental em blocos casualizados no esquema fatorial 5 x 7, sendo cinco cultivares de alface (Isabela, Vera, Verônica, Veneranda e Cinderela x sete ambientes de cultivo (campo aberto, sombrite 30%, sombrite 40%, sombrite 50%, termorefletora 30%, termorefletora 40%, termorefletora 50%  com 4 repetições, tendo um total de 140 parcelas compostas de 24 plantas cada, das quais 12 foram utilizadas para avaliações   da altura da planta realizada semanalmente após o transplante e número de dias para emissão do pendão foral a partir da semeadura. Foi observado que na maioria dos ambientes as cultivares ‘Verônica’ e ‘Cinderela’ tiveram uma menor média de dias para pendoar assim  como maior  comprimento do  caule  e o ambiente  com  termorefletora 50% apresentou melhores condições para o cultivo de alface. Conclui-se que a cultivar ‘Isabela’  é a mais  tolerante ao pendoamento  e o ambiente  com  termorefletora 50% apresentou-se como o mais favorável ao cultivo de alface para região de Cáceres-MT, pois nele as cultivares demoraram mais para pendoar.

  18. Educação ao ar livre pela aventura: o aprendizado de valores morais em expedições à natureza Education outdoors through adventure: learning moral values in nature expeditions

    Directory of Open Access Journals (Sweden)

    Flavio Theodor Kunreuther

    2012-06-01

    Full Text Available A educação ao ar livre, por meio de cursos no formato expedição, ainda acontece de forma tímida no Brasil. Entende-se por expedição uma experiência educacional contínua, de múltiplos dias, em que alunos e instrutores aventuram-se em um trajeto em área remota da natureza de forma autossuficiente. O presente estudo analisa os cursos desse tipo. Por meio de entrevistas e questionários semiestruturados, investigou-se a aprendizagem dos alunos segundo suas próprias percepções e as dos educadores da instituição, com ênfase no desenvolvimento moral do indivíduo. Como parte do estudo de caso sobre um aluno adolescente participante de um dos cursos, entrevistou-se também uma psicóloga que coordena um abrigo para menores. Os resultados encontrados indicam que os cursos de educação ao ar livre caracterizam-se por experiências que estimulam trabalhos em grupo, debates sobre justiça e solidariedade, e reflexões sobre valores e princípios como coragem, esforço pessoal, disciplina, respeito e superação de limites. Os resultados também indicam que tal proposta educacional aufere experiências sensíveis e de conexão do ser humano com a natureza. Muito embora haja potencial educacional para a educação ao ar livre, a atuação do educador perante seus alunos é fundamental para que as experiências sejam física e psicologicamente seguras, alcancem seus potenciais pedagógicos de desenvolvimento da moralidade e ajudem as pessoas a desenvolverem uma consciência ambiental, manifestada por meio de ações concretas ao retornarem dos cursos para suas comunidades.Open air education through courses organized as expeditions is still incipient in Brazil. We understand an expedition as a continued educational experience taking several days in which students and instructors venture into a remote natural area in a self-sufficient way. The present study analyzes courses of this type. Using interviews and semi-structured questionnaires, it

  19. Small angle Ar2+ + Ar collisions

    International Nuclear Information System (INIS)

    Stevens, J.J.

    1983-01-01

    Electron capture in Ar 2+ + Ar is studied at low keV energies. Using Ar 2+ + He collisions as a calibration, it is shown that the dominant single electron capture process is endothermic and of the type Ar 2+ ( 3 P) + ArAr + ( 2 P) + Ar + (3s 2 3p 4 nI), with nI primarily being 3d and 4p. Weaker exothermic processes are also found and are due mainly to the existence of long-lived highly-excited states in the incident Ar 2+ beam. The direct scattering and double electron capture processes are also studied. Direct scattering occurs with no target excitation. Differential cross sections are presented for the collision processes. The single electron capture results are interpreted using a simple model in which a strongly attractive intermediate state couples with incident and outgoing channels

  20. Identification of excess 40Ar by the 40Ar/39Ar age spectrum technique

    International Nuclear Information System (INIS)

    Lanphere, M.A.; Dalrymple, G.B.

    1976-01-01

    40 Ar/ 39 Ar incremental heating experiments on igneous plagioclase, biotite, and pyroxene that contain known amounts of excess 40 Ar indicate that saddle-shaped age spectra are diagnostic of excess 40 Ar in igneous minerals as well as in igneous rocks. The minima in the age spectra approach but do not reach the crystallization age. Neither the age spectrum diagram nor the 40 Ar/ 36 Ar versus 39 Ar/ 36 Ar isochron diagram reliably reveal the crystallization age in such samples. (Auth.)

  1. Influência da Estrutura de Governança Corporativa na Eficiência Financeira: Evidências de Empresas Brasileiras de Capital Aberto

    Directory of Open Access Journals (Sweden)

    Tatiana Marceda Bach

    2015-12-01

    Full Text Available O agente é responsável por atuar no gerenciamento dos interesses do principal e maximizar os lucros da empresa, com o propósito de coordenar e controlar as atividades realizadas por ambos surge a governança corporativa, visando gerar maiores retornos e eficiência. Este artigo objetiva analisar a influência da governança corporativa na eficiência das empresas de capital aberto listadas na BOVESPA. De natureza quantitativa-descritiva, foram analisados dados de 284 empresas no período de 2008 a 2013. Para o cálculo da eficiência foi utilizado a Análise por Envoltória de Dados (DEA e, para a análise dos dados, utilizou-se o software UNCINET 6.0 e o pacote estatístico STATA versão 11.0. A governança foi avaliada a com base no estudo de Silveira (2004 e com base nas recomendações do código de melhores práticas de Governança Corporativa de agências regulamentadoras. A eficiência dos bancos, ao longo de 6 anos, mostrou-se estável e superior ao das demais empresas. A influência da governança corporativa na eficiência é explicada, para as empresas, pelas variáveis estrutura do conselho e estrutura de propriedade, para os bancos, é explicada pelas variáveis acesso às informações, estrutura do conselho, crescimento da receita e ativo total. Este estudo contribui para a identificação das empresas e bancos eficientes, que a partir deste resultado, podem modificar suas ações e estratégias para aumentar sua eficiência corporativa. Para a governança, as variáveis que se mostraram inversamente proporcionais à eficiência poderiam ser revistas pelas empresas com o propósito de contribuir para um maior crescimento e maximização de seus lucros.

  2. Mapeamento do ambiente térmico de aviários de postura abertos em sistema vertical de criação

    Directory of Open Access Journals (Sweden)

    Diogo J. de R. Coelho

    2015-10-01

    Full Text Available RESUMOObjetivou-se, com este trabalho monitorar, em tempo real, o ambiente térmico de um aviário de postura e realizar o mapeamento completo da distribuição das variáveis temperatura do ar, umidade relativa do ar e índice de temperatura e umidade no alojamento. O trabalho foi conduzido no mês de janeiro de 2013 em uma granja comercial de aves de postura, sistemas verticais, com seis andares de gaiolas. O aviário é totalmente automatizado possuindo 100.000 aves alojadas na densidade de 300 cm2 ave-1. A partir dos dados coletados foram determinadas as médias de temperatura e umidade relativa do ar para período diurno e noturno de diferentes posições na instalação. Os mapas térmicos resultantes demostram que ocorreu uma variabilidade térmica em diferentes posições espaciais no interior do aviário, com a região central apresentando temperaturas superiores às das extremidades porém dentro da faixa de conforto térmico das aves considerando a situação de temperaturas médias, durante calor extremo a temperatura interna na instalação alcançou 33 oC. A umidade relativa do ar apresentou pequenas variações durante o dia e maiores no período da noite. Em relação ao índice de temperatura e umidade a maior parte da instalação permaneceu dentro da faixa de conforto.

  3. Tecnologias de dados abertos para interligar bibliotecas, arquivos e museus: um caso machadiano

    Directory of Open Access Journals (Sweden)

    Antonio Laurindo dos Santos Neto

    Full Text Available O artigo propõe um caso fictício para ilustrar o uso das tecnologias de Dados Abertos Interligados como mecanismos para tornar interoperáveis informações em acervos de bibliotecas, arquivos e museus, utilizando como exemplo as informações sobre o escritor Machado de Assis e sua obra. Utilizou-se como método o estudo de um caso restrito e ilustrativo, não exaustivo. Aplicaram-se diferentes vocabulários para interligação dos dados e para sua representação, utilizando os princípios do Linked Data; sugere-se que os profissionais da informação usufruam dessa potencialidade e busquem novas aplicações para ampliar a interoperabilidade dos dados disponíveis na Web.

  4. O espaço político aberto pela leitura literária

    Directory of Open Access Journals (Sweden)

    Leonardo Pinto de Almeida

    2013-01-01

    Full Text Available O presente artigo se propõe questionar sobre o espaço político aberto pela leitura literária. Especificando a literatura como uma tentativa de compreensão de problemas relacionados à existência, sublinhamos como a leitura literária coloca em questão nossas convicções e verdades defendidas cotidianamente. Para tanto, compreendemos as relações tecidas entre a linguagem, o poder e a resistência no seio da experiência literária. Concluímos que a leitura literária é atravessada por formas de resistência às palavras de ordem que circulam de forma hegemônica em nossa sociedade, disponibilizando assim uma transformação em nossa rede afetiva e cognitiva.

  5. Spectroanalytical investigations on inductively coupled N2/Ar and Ar/Ar high frequency plasmas

    International Nuclear Information System (INIS)

    Malinowski, P.; Mazurkiewicz, M.; Nickel, H.

    1981-03-01

    In order to improve the detection limits of trace elements in corrosion products of metallic materials, the inductively coupled plasma excitation source (ICP) was applied for spectroscopic analysis. Besides optimizing the working conditions for the mentioned materials, the fundamental research clearing the excitation processes in ICP was carried out. Basicly, two plasma systems were investigated: the nitrogen cooled N 2 /Ar- and pure Ar/Ar-plasma. The computed detection limits for 8 chosen elements are between 0.1 and 50 μg ml -1 in both plasmas. The advantage of ion lines was clearly present; in N 2 /Ar-plasma it was larger than in Ar/Ar-plasma. The excitation temperatures measured with help of ArI, FeI and ZnI lines rise with increasing power and decreasing distance from the induction coil. The distribution of Zn excitation temperature in N 2 /Ar-plasma as well as the measured N + 2 rotational and CN vibrational temperatures indicate, that the toroidal structure of Ar/Ar-plasma is not analogue to the N 2 /Ar-plasma. The values of the various excitation temperatures (Ar, Fe, Zn) and the differences between the excitation, vibration, rotation and ionization temperatures (Tsub(i) > Tsub(n) = Tsub(vib) > Tsub(rot)) indicate an absence of thermal equilibrium in the concerned system. (orig.)

  6. Carta ao Leitor

    Directory of Open Access Journals (Sweden)

    Editorial Editorial

    2014-02-01

    Full Text Available ApresentaçãoO Centro de Educação a Distância – CEAD/Unimontes foi inaugurado em 2011 em histórico de ricas experiências vivenciadas pela Universidade Estadual de Montes Claros – Unimontes ao longo de 15 anos.Uma jornada de esforços conjuntos e uma estima apaixonada pela educação e pelo conheci-mento científico carecia, em seu núcleo, de uma plataforma que reunisse todas as perspectivas constitutivas de sua história e finalidade. Um anseio crescente da instituição que se desdobra e desdobrará em produtos e iniciativas de fomento em pesquisa. Em 2012, como fruto gerado di-retamente do âmago dessas necessidades unidas ao cenário nacional de valorização crescente da pesquisa científica, surge a Revista Multitexto.A Revista Multitexto nasce como um periódico em movimento. São contribuições de aborda-gens múltiplas num ensejo genuíno e único de progressão científica em pesquisa. Um marco para os estudos na área de ensino a distância numa oferta interdisciplinar. Unidade na diversidade: a grande proposta da revista. Espaço aberto para pesquisadores e entusiastas. Multipliquem-se os multitextos em contribuições múltiplas.Sobre a Revista MultitextoPublicação semestral do Centro de Educação a Distância da Universidade Estadual de Montes Claros – CEAD/Unimontes, que contribui na área de conhecimento produzida pelas fenomenologias e áreas correlatas em Educação a Distância, com foco interdisciplinar. Aberta em 2012, a Revista Multitexto recebe colaborações de pesquisadores em ensino a dis-tância e demais áreas. É meta referencial da revista abordar questões conceituais e metodológicas, bem como, os desenvolvimentos da pesquisa, aplicada ou teórica, na área de educação à distância (EAD; difundir a produção científica de pesquisadores da área de educação à distância (EAD, inseridos em Institutos de pesquisa e de educação superior no Brasil; propiciar um espaço para o

  7. Kinetics of Ar isotopes during neutron irradiation: 39Ar loss from minerals as a source of error in 40Ar/39Ar dating

    International Nuclear Information System (INIS)

    Hess, J.C.; Lippolt, H.J.

    1986-01-01

    The loss of 39 Ar from minerals in the course of neutron activation for 40 Ar/ 39 Ar dating is studied by directly measuring the loss rates in vacuum-sealed ampoules. Biotite shows 39 Ar losses between 0.1% and 16%. These losses are predominantly due to diffusion processes from K-poor alteration-phase intergrowths in the biotites at the elevated temperatures during the irradiation. Estimates for the irradiation temperatures range from 150 0 to 180 0 C. Direct 39 Ar recoil loss from biotite seems to be minor compared to difussion loss of recoil-implanted 39 Ar. Precise 40 Ar/ 39 Ar dating of biotites therefore requires the measurement of the 39 Ar losses during irradiation. Glauconite loses not only neutron-induced Ar isotopes ( 39 Ar: 20-22%, 37 Ar: 17-19%) but also radiogenic 40 Ar(∼9%). Slight 39 Ar losses are also observed for light micas (0.2% and 0.35%), hornblendes (0.1%) and sanidines (200 and 700 ppm). 25 refs.; 4 figs.; 6 tabs

  8. Efeito de níveis de água, coberturas do solo e condições ambientais na temperatura do solo e no cultivo de morangueiro em ambiente protegido e a céu aberto

    OpenAIRE

    Pires,Regina C. de M.; Folegatti,Marcos V.; Pedro Júnior,Mário J.; Sakai,Emílio; Passos,Francisco A.; Arruda,Flávio B.; Calheiros,Rinaldo de O.

    2004-01-01

    A temperatura do solo é um importante parâmetro no cultivo do morangueiro, pois interfere no desenvolvimento vegetativo, na sanidade e na produção. O objetivo do presente trabalho foi avaliar o efeito de diferentes níveis de água, coberturas de canteiro em campo aberto e em ambiente protegido, na temperatura máxima do solo no cultivo do morangueiro. Foram realizados dois experimentos: um em cultivo protegido e outro a campo aberto, em Atibaia - SP, em esquema fatorial 2 x 3 (coberturas do sol...

  9. Influences of atom Ar on Ar at C60 + Ar at C60 collisions

    International Nuclear Information System (INIS)

    Zhao Qiang; Zhou Hongyu; Zhang Fengshou

    2007-01-01

    A semi-emperical molecular dynamics model was developed. The central collisions of C 60 + C 60 and Ar at C 60 + Ar at C 60 at the same incident energy were investigated within this model. The fullerene dimers could be formed by a self-assembly of C 60 fullerene, and the new fullerene structure like 'peanut' could be formed by a self-assembly of Ar at C 60 . It was found that atom Ar had a great effect on the collision of Ar at C 60 + Ar at C 60 . (authors)

  10. Exposição ao mercúrio e ao arsênio em Estados da Amazônia: síntese dos estudos do Instituto Evandro Chagas/FUNASA Exposure to mercury and arsenic in Amazon States: a summary of studies by the Evandro Chagas Institute/FUNASA

    Directory of Open Access Journals (Sweden)

    Elisabeth C. de Oliveira Santos

    2003-06-01

    Full Text Available Este artigo é uma revisão das pesquisas da Seção de Meio Ambiente do Instituto Evandro Chagas/FUNASA sobre exposição ao mercúrio (Hg no vale do rio Tapajós e Estado do Acre, e exposição ao arsênio (As através de resíduos da exploração de manganês (Mn realizada pela ICOMI deixados no Porto de Santana-AP. Em relação ao mercúrio, têm sido pesquisadas populações sob risco através da via respiratória ou alimentar. No primeiro caso, os trabalhadores de casas de compra e venda de ouro têm apresentado teores mais elevados de Hg em urina do que os garimpeiros estudados. No segundo caso, as populações ribeirinhas têm mostrado níveis diferenciados de exposição (Hg em cabelo. Comunidades ribeirinhas situadas em áreas não afetadas pelo mercúrio da garimpagem e com hábitos alimentares semelhantes às de área de risco têm sido avaliadas, visando a construção de parâmetros de normalidade regional. São também pesquisados os teores de Hg em materiais ambientais e na biota aquática. Os estudos de saúde humana e ambiente na cidade de Santana-AP objetivaram avaliar as fontes e possíveis vias de exposição da população da comunidade do Elesbão ao arsênio. Verificou-se a existência de fonte de risco através dos rejeitos de Mn, porém os níveis de As na água consumida pela população mostraram-se dentro dos parâmetros de normalidade. As médias encontradas em sangue e cabelo coincidem com médias de normalidade referidas na literatura, em populações não expostas, e as associações entre variáveis epidemiológicas, avaliação clínico-laboratorial e os teores de arsênio não mostraram significância estatística.This article is a review of the studies carried out by Environmental Section of the Evandro Chagas Institute/FUNASA on mercury (Hg exposure in the Tapajós river basin, and arsenic exposure (As due to residues of the manganese (Mn exploration, performed by ICOMI and left at the port of Santana

  11. Avaliação da sensibilidade da goiabeira 'Pedro Sato' ao ozônio

    Directory of Open Access Journals (Sweden)

    Regina Maria de Moraes

    2011-09-01

    Full Text Available O objetivo deste trabalho foi avaliar a sensibilidade da goiabeira 'Pedro Sato' ao ozônio (O3, em comparação à cultivar Paluma, descrita como sensível. Oito plantas de cada cultivar foram submetidas separadamente a ar filtrado e a ar filtrado + O3, cinco horas por dia, durante quatro dias. Foram avaliadas fotossíntese (Asat, injúrias foliares visíveis e concentração de antocianinas e taninos. Plantas das duas cultivares também foram expostas, durante três meses, a condições ambientais em local contaminado por O3, tendo-se avaliado fotossíntese, injúrias foliares e crescimento. Plantas fumigadas com O3 apresentaram redução de Asat e da atividade fotoquímica, além de manifestação de injúrias foliares. 'Paluma' apresentou maior redução de Asat, injúrias foliares mais severas e redução de taninos. Quando exposta ao ambiente contaminado, 'Paluma' apresentou trocas gasosas mais altas, mas apresentou redução de Asat 30 dias antes que 'Pedro Sato'. O crescimento não foi afetado em 'Pedro Sato', cujas injúrias foliares tiveram menor incidência, severidade e precocidade do que em 'Paluma'. A menor taxa de crescimento de 'Paluma' indica maior sensibilidade ao O3. Apesar de responder com menor intensidade ao estresse induzido pelo O3, a cultivar Pedro Sato não pode ser considerada tolerante, pois apresenta danos fotoquímicos, injúrias foliares e alterações nos conteúdos de metabólitos secundários quando exposta a esse poluente.

  12. Simultaneous measurement of the 37Ar and 39Ar activity

    International Nuclear Information System (INIS)

    Fisenko, A.V.

    1978-01-01

    A method for simultaneous measurement of 37 Ar and 39 Ar activities, based on the different radiation penetrabilities of these isotopes is described. Two versions are realized. In the first case, a two-section detector is used whose partition partially transmits 39 Ar β-radiation and fully absorbs 37 Ar Auger electrons. A mixture of 37 Ar and 39 Ar is introduced into an internal counter operating at anticoincidences with an external counter. In the second version, a scintillation detector is used as an external counter, while the 37 Ar- 39 Ar mixture is introduced into a gas counter with a thin cathode. The rated detection efficiency of 37 Ar radiation in both versions is 80%. When measurement duration is 500 h, the sensitivity is approximately 10 -14 and 6x10 -15 Ci for 39 Ar and 37 Ar respectively

  13. Determination of Ar metastable atom densities in Ar and Ar/H2 inductively coupled low-temperature plasmas

    International Nuclear Information System (INIS)

    Fox-Lyon, N; Knoll, A J; Oehrlein, G S; Franek, J; Demidov, V; Koepke, M; Godyak, V

    2013-01-01

    Ar metastable atoms are important energy carriers and surface interacting species in low-temperature plasmas that are difficult to quantify. Ar metastable atom densities (N Ar,m ) in inductively coupled Ar and Ar/H 2 plasmas were obtained using a model combining electrical probe measurements of electron density (N e ) and temperature (T e ), with analysis of spectrally resolved Ar plasma optical emission based on 3p → 1s optical emission ratios of the 419.8 nm line to the 420.1 nm line. We present the variation of N Ar,m as the Ar pressure and the addition of H 2 to Ar are changed comparatively to recent adsorption spectroscopy measurements. (paper)

  14. 40Ar/39Ar geochronology of terrestrial pyroxene

    Science.gov (United States)

    Ware, Bryant; Jourdan, Fred

    2018-06-01

    Geochronological techniques such as U/Pb in zircon and baddeleyite and 40Ar/39Ar on a vast range of minerals, including sanidine, plagioclase, and biotite, provide means to date an array of different geologic processes. Many of these minerals, however, are not always present in a given rock, or can be altered by secondary processes (e.g. plagioclase in mafic rocks) limiting our ability to derive an isotopic age. Pyroxene is a primary rock forming mineral for both mafic and ultramafic rocks and is resistant to alteration process but attempts to date this phase with 40Ar/39Ar has been met with little success so far. In this study, we analyzed pyroxene crystals from two different Large Igneous Provinces using a multi-collector noble gas mass spectrometer (ARGUS VI) since those machines have been shown to significantly improve analytical precision compared to the previous single-collector instruments. We obtain geologically meaningful and relatively precise 40Ar/39Ar plateau ages ranging from 184.6 ± 3.9 to 182.4 ± 0.8 Ma (2σ uncertainties of ±1.8-0.4%) and 506.3 ± 3.4 Ma for Tasmanian and Kalkarindji dolerites, respectively. Those data are indistinguishable from new and/or published U-Pb and 40Ar/39Ar plagioclase ages showing that 40Ar/39Ar dating of pyroxene is a suitable geochronological tool. Scrutinizing the analytical results of the pyroxene analyses as well as comparing them to the analytical result from plagioclase of the same samples indicate pure pyroxene was dated. Numerical models of argon diffusion in plagioclase and pyroxene support these observations. However, we found that the viability of 40Ar/39Ar dating approach of pyroxene can be affected by irradiation-induced recoil redistribution between thin pyroxene exsolution lamellae and the main pyroxene crystal, hence requiring careful petrographic observations before analysis. Finally, diffusion modeling show that 40Ar/39Ar of pyroxene can be used as a powerful tool to date the formation age of mafic

  15. 40Ar/39Ar studies of deep sea igneous rocks

    International Nuclear Information System (INIS)

    Seidemann, D.

    1978-01-01

    An attempt to date deep-sea igneous rocks reliably was made using the 40 Ar/ 39 Ar dating technique. It was determined that the 40 Ar/ 39 Ar incremental release technique could not be used to eliminate the effects of excess radiogenic 40 Ar in deep-sea basalts. Excess 40 Ar is released throughout the extraction temperature range and cannot be distinguished from 40 Ar generated by in situ 40 K decay. The problem of the reduction of K-Ar dates associated with sea water alteration of deep-sea igneous rocks could not be resolved using the 40 Ar/ 39 Ar technique. Irradiation induced 39 Ar loss and/or redistribution in fine-grained and altered igneous rocks results in age spectra that are artifacts of the experimental procedure and only partly reflect the geologic history of the sample. Therefore, caution must be used in attributing significance to age spectra of fine grained and altered deep-sea igneous rocks. Effects of 39 Ar recoil are not important for either medium-grained (or coarser) deep-sea rocks or glasses because only a small fraction of the 39 Ar recoils to channels of easy diffusion, such as intergranular boundaries or cracks, during the irradiation. (author)

  16. Geological Dating by 40 Ar - 39 Ar method

    International Nuclear Information System (INIS)

    Vollbert Romero, M.E.

    1992-01-01

    The isotope 40 K is radioactive, it decays to 40 Ar stable. The number of 40 Ar atoms produced from 40 K, permits to calculate the date of rocks and minerals. This dating technique is named 'Conventional K-Ar Dating Method'. The 40 Ar - 39 Ar dating method permits to calculate the age of rocks and minerals eliminating the limitation of the K-Ar method by calculating potassium and argon concentrations in a single measurement of the ratio of argon isotopes. In this work, the irradiation of the sample with fast neutrons in the nuclear reactor was established. 39 Ar is obtained from the induced reaction 39 K (n,p) 39 Ar. Thus the ration of 40 Ar - 39 Ar allows to obtain the date of rocks and minerals. This ratio was measured in a mass spectrometer. If the measurement of argon concentration in the sample is carried out at different increasing temperature values, it is possible to get information of paleotemperatures. The number of atoms 39 Ar is a function of the number 39 K atoms, irradiation time, neutrons flux, its energy E and the capture cross section σ of 39 K. These parameters are calculate indirectly by obtaining the so called 'J value ' by using a standard mineral with known age (HD-BI y Biot-133), this mineral is irradiated together with the unknown age sample. The values of 'J' obtained are in the interval of 2.85 a 3.03 (x 10 - 3)J/h. Rocks from 'Tres Virgenes' were dated by the method described in this work, showing an agreement with previous values of different authors. The age of this rocks are from Cenozoico era, mainly in the miocene period. (Author)

  17. Impacto do sistema de aspiração traqueal aberto e fechado na incidência de pneumonia associada à ventilação mecânica: revisão de literatura Impact of the open and closed tracheal suctioning system on the incidence of mechanical ventilation associated pneumonia: literature review

    Directory of Open Access Journals (Sweden)

    Fernanda Maia Lopes

    2009-03-01

    Full Text Available A pneumonia é a infecção nosocomial mais comum em unidades de terapia intensiva, sendo a ventilação mecânica um fator fortemente associado ao seu desenvolvimento. O objetivo deste estudo foi descrever o impacto do sistema de aspiração traqueal aberto e fechado na incidência de pneumonia associada à ventilação mecânica. Realizou-se uma pesquisa na base de dados Pubmed para identificar tentativas controladas aleatórias, publicadas no período de 1990 a novembro de 2008. Nove estudos foram incluídos. Dos estudos revisados, sete não observaram redução significante da incidência de pneumonia associada à ventilação mecânica com o uso do sistema fechado comparado ao aberto, sendo que dois destes verificaram que o uso do sistema fechado resulta em incremento nas taxas de colonização sem incrementar sua incidência e um observou que o uso do sistema fechado não incrementa a colonização do trato respiratório e reduz a expansão de infecção resultando em redução nas taxas de sepse. Apenas dois estudos verificaram redução na incidência de pneumonia associada à ventilação mecânica com o uso do sistema fechado, e um destes revelou um risco 3.5 vezes maior de desenvolvimento desta infecção com o sistema aberto. Os resultados sugerem que o impacto do sistema de aspiração traqueal aberto e fechado é semelhante para o desenvolvimento da pneumonia associada à ventilação mecânica, assim a escolha do tipo de sistema de aspiração traqueal deve ser baseada em outros parâmetros. Entretanto, o sistema fechado aumenta o risco de colonização do trato respiratório, mas apresenta como vantagens a manutenção da ventilação mecânica e o menor prejuízo hemodinâmico.Pneumonia is the most common nosocominal infection in intensive care units and mechanical ventilation is a significant factor associated to its development. The objective of this study was to describe the impact of the open and closed tracheal suction

  18. Standardization of 40Ar-39Ar dating facility at KDMIPE, ONGC, Dehradun

    International Nuclear Information System (INIS)

    Rathore, S.S.; Singh, M.P.; Vijan, A.R.; Bansal, M.; Prabhu, B.N.; Misra, K.N.

    2003-01-01

    In the pursuit of acquiring state of the art technology, efforts were being made for last more than two years to establish 40 Ar- 39 Ar dating facility at KDMIPE. The 40 Ar- 39 Ar dating technique is an analytical conversion of the conventional K-Ar dating method. In this method, the sample to be dated is first irradiated in a nuclear reactor to transform a portion of 39 K to 39 Ar by the fast neutron reaction i.e. 39 K(n, p) 39 Ar. After irradiation, the sample is placed in an ultra-high vacuum system and the argon extracted from it by fusion is purified and analyzed isotopically in a mass spectrometer. The relative abundances of 40 Ar, 39 Ar, 37 Ar and 36 Ar are measured. The 40 Ar/ 39 Ar K is determined, where 40 Ar is the radiogenic argon, and 39 Ar K is the 39 Ar produced from 39 K during the irradiation. The 40 Ar/ 39 Ar K ratio is proportional to the 40 Ar/ 40 K ratio in the sample and, therefore, is proportional to age

  19. Temperature and pressure effects on 40Ar-39Ar systematics

    International Nuclear Information System (INIS)

    Ozima, M.; Kaneoka, I.; Yanagisawa, M.

    1979-01-01

    The effects of thermal and compressional treatment on 40 Ar- 39 Ar systematics have been investigated on three artificially heated biotite samples (heated for 1 hour at 700 0 C and 860 0 C in air and 700 0 C in vacuum respectively) and uniaxially compressed granite (p=1400 bar) and basalt samples (p=1660 bar). The 40 Ar- 39 Ar results for the disturbed samples are compared with those for undisturbed samples. Except for the vacuum-heating case, the effects of the disturbances may be interpreted as the combined effect of a partial loss of radiogenic 40 Ar from the sample and an incorporation of air Ar into the sample. Common diagnostic effects are (1) reduction of the total fusion age, (2) distortion of the age spectrum and, if the degree of the partial Ar loss is small (3) approximate preservation of the isochron age, and (4) reduction of the intercept value ( 40 Ar/ 36 Ar) in the isochron plot. The features observed in the age spectra of artificially disturbed samples are rather common in geologically disturbed samples, suggesting that the artificial disturbances simulate the effects of geological disturbances on 40 Ar- 39 Ar systematics. (Auth.)

  20. Parâmetros hematológicos e bioquímicos da tilápia-do-Nilo (Oreochromis niloticus L. sob estresse por exposição ao ar Hematological parameters of Nile Tilapia (Oreochromis niloticus L. under air exposure stress

    Directory of Open Access Journals (Sweden)

    Roberta Dias da Silva

    2012-12-01

    Full Text Available No presente trabalho avaliaram-se os parâmetros hematológicos e bioquímicos de exemplares adultos de tilápias (Oreochromis niloticus sob a influência do fator estresse fisiológico em animais submetidos à exposição ao ar durante a engorda em sistema raceway. Foram analisados o eritrograma, teor de hemoglobina, volume globular, o volume corpuscular médio (VCM, a hemoglobina corpuscular média (HCM, a concentração de hemoglobina corpuscular média (CHCM, o leucograma, contagem diferencial de leucócitos, o plaquetograma, a glicose, a proteína total, o colesterol, o triglicerídeo e os eletrólitos (cálcio, cloretos, sódio e potássio. Os resultados revelaram que houve uma homogeneidade de distribuição para hemácias, volume globular, hemoglobina, índices hemantimétricos, proteína total, glicose, colesterol, e íons séricos, indicados pelos valores relativamente baixos do coeficiente de variação. Houve correlação positiva somente para leucócitos totais, células de defesa orgânica (neutrófilos e linfócitos, glicose, colesterol, sódio e cálcio. Quanto ao leucograma, à medida que os animais foram expostos ao ar, o número de leucócitos diminuiu gradativamente (leucopenia, ocorrendo simultaneamente neutrofilia e linfopenia. O índice glicêmico constituiu um bom indicador de estresse fisiológico, devido à hiperglicemia (82,0±20,88mg/dL demonstrada nos tratamentos. A exposição ao ar constituiu um fator de desequilíbrio na homeostase iônica, e na síntese de colesterol endógeno. Entretanto, o tempo de recuperação não ocasionou a completa reabilitação fisiológica frente ao desafio imposto.The present study evaluated the hematological and biochemical parameters of adult tilapia (Oreochromis niloticus under the influence of the physiological stress factor in animals submitted to air exposure during fattening in raceway system. Blood cell count, hemoglobin, hematocrit, mean corpuscular volume (MCV, mean

  1. Sustentabilidade empresarial e o impacto no custo de capital próprio das empresas de capital aberto Sustainable development and consequences for equity costs in public companies

    Directory of Open Access Journals (Sweden)

    Lílian Simone Aguiar da Silva

    2006-12-01

    Full Text Available Este trabalho apresenta o impacto no custo de capital próprio para as empresas brasileiras de capital aberto face à adoção dos princípios de sustentabilidade. O conceito de desenvolvimento sustentável tem se aprimorado num processo contínuo de reavaliação da relação existente entre: crescimento econômico, a sociedade civil e o meio ambiente. O triple-bottom-line das dimensões econômica, ambiental e social da sustentabilidade tem emergido como um modelo de interpretação pelas empresas, embora cada uma dessas dimensões represente um grande desafio. O segmento corporativo vem atendendo às demandas cada vez maiores da sociedade frente a essas questões, ficando a dúvida quanto à legitimidade dessas ações e o questionamento relativo ao papel das empresas na economia e na sociedade. Para avaliar o impacto no custo de capital próprio, foi implementado um modelo de decomposição do beta em medidas contábeis de risco, incluindo uma variável referente à sustentabilidade. O resultado confirma a expectativa de que ao aderir aos padrões de sustentabilidade a empresa reduz o risco corporativo medido pelo risco sistemático, determinando a redução do custo de capital e aumento do valor econômico.This article provides an analysis of equity costs in Brazilian public companies regarding the adoption of sustainability principles. The concept of sustainable development has evolved considering the relation among economic growth, the society and the environment. The triple-bottom-line of economic, environmental, and social dimensions has emerged as an interpretation model by companies, although each of these dimensions may present a challenge. The corporate sector has faced an increasing demand from society regarding these sustainability concepts, though the actions and the role to be played by companies within this context are still being questioned. Equity costs were analyzed by a multivariate regression of beta on accounting measures

  2. 39Ar/Ar measurements using ultra-low background proportional counters

    International Nuclear Information System (INIS)

    Hall, Jeter; Aalseth, Craig E.; Bonicalzi, Ricco M.; Brandenberger, Jill M.; Day, Anthony R.; Humble, Paul H.; Mace, Emily K.; Panisko, Mark E.; Seifert, Allen

    2016-01-01

    Age-dating groundwater and seawater using the 39 Ar/Ar ratio is an important tool to understand water mass-flow rates and mean residence time. Low-background proportional counters developed at Pacific Northwest National Laboratory use mixtures of argon and methane as counting gas. We demonstrate sensitivity to 39 Ar by comparing geological (ancient) argon recovered from a carbon dioxide gas well and commercial argon. The demonstrated sensitivity to the 39 Ar/Ar ratio is sufficient to date water masses as old as 1000 years. - Highlights: • 39 Ar/Ar age dating is important for understanding environmental water migration. • Ultra low background proportional counters have been developed. • 39 Ar is detected in atmospheric argon at a rate of 70.3 counts per day. The demonstrated background is 166 counts per day. • Age dating is possible for water with underground residence time of up to 1000 years.

  3. 40Ar/39Ar age calibration against counted annuallayers

    DEFF Research Database (Denmark)

    Storey, Michael; Stecher, Ole

    2008-01-01

    The 40Ar/39Ar method, based on the decay of the naturally occurring radioactive isotope 40K, is capable of producing ages with precision better than ± 0.1 %. However, accuracy is limited to no better than 1 % mainly due to the relatively large uncertainty in the 40K decay constants. One approach...... worth exploring for an improved absolute age basis for the 40Ar/39Ar system is through cross-calibration with counted annual layers (e.g. tree rings, varves and ice cores). North Atlantic Ash Zone (NAAZ) II is found within the dated part of the annual Greenland ice core record. NAAZ II has been...... correlated to the Icelandic peralkaline rhyolitic Thorsmörk ignimbrite. We will present preliminary 40Ar/39Ar results on the age of this eruption...

  4. 40Ar/39Ar and K-Ar dating of altered glassy volcanic rocks: the Dabi Volcanics, P.N.G

    International Nuclear Information System (INIS)

    Walker, D.A.; McDougall, I.

    1982-01-01

    K-Ar and 40 Ar/ 39 Ar ages have been determined for altered submarine tholeiitic and boninite (high-Mg andesite) lavas from the Dabi Volcanics, Cape Vogel Peninsula, Papua New Guinea. 40 Ar/ 39 Ar whole rock total fusion and plateau ages identify a Late Paleocene age for the tholeiitic lavas (58.9 +- 1.1 Ma), and also for the boninitic lavas (58.8 +- 0.8 Ma). Apparent K-Ar ages for the same samples range from 27.2 +- 0.7 to 63.9 +- 4.5 Ma, and young K-Ar ages for glassy boninites are probably due to variable radiogenic 40 Ar( 40 Ar*) loss. These new ages effectively reconcile previously ambiguous age data for the Dabi Volcanics, and indicate contemporaneous tholeiitic and boninitic volcanism occurring in southeast PNG during the Late Paleocene. Smectites, developed as alteration products after glass in oceanic lavas commonly do not retain 39 Ar during or subsequent to irradiation, but in some cases may contain 40 Ar*. The results are discussed. (author)

  5. Instrumentos relacionados ao diabetes mellitus adaptados e validados para a cultura brasileira

    Directory of Open Access Journals (Sweden)

    Raquel Curcio

    2011-06-01

    Full Text Available Trata-se de um estudo de revisão integrativa, cujo objetivo foi buscar evidências disponíveis na literatura sobre os instrumentos e escalas relacionados ao diabetes mellitus adaptados e validados para a cultura brasileira. Após busca nas bases eletrônicas BDENF, SciELO, LILACS, foram incluídos sete instrumentos que atenderam aos critérios de inclusão: Diabetes Mellitus Knowledge (DKN-A; Diabetes Mellitus Attitude (ATT-19; Diabetes Quality of Life Measure (DQOL-Brasil; Diabetes Quality of Life for Youths (DQOLY-Brasil; Diabetes 39 (D-39; Insulin Management Diabetes Self-efficacy (IMDSES; Problem Areas in Diabetes (PAID e Summary of Diabetes Self-Care Activities Questionnaire (QAD. Os resultados permitiram traçar uma comparação entre os instrumentos disponíveis, além de conhecer as limitações quanto ao processo de validação e aplicação clínica. Espera-se que esse estudo possa contribuir para uma maior divulgação dos instrumentos relacionados ao diabetes mellitus disponíveis para a cultura brasileira, e oferecer subsídios para a sua utilização em pesquisa ou assistência de enfermagem.

  6. 40Ar-39Ar stepheating studies of clay concentrates from Irish orebodies

    International Nuclear Information System (INIS)

    Halliday, A.N.

    1978-01-01

    40 Ar- 39 Ar step heating analyses of clay concentrates from the Gortdrum and Tynagh orebodies (Ireland) previously dated by conventional K-Ar, indicate major losses of 39 Ar (32 to 45%) and rad. 40 Ar (25 to 35%) during the irradiation. The proportion of rad. 40 Ar loss, unlike that of 39 Ar, increases with J-value. The difference between 39 Ar and rad. 40 Ar proportion losses is related to the mineralogy and grain intimacy. These also affect the stepwise release patterns - the Gortdrum concentrates yield age spectra very consistent with 39 Ar recoil predictions, whereas the Tynagh concentrates in which the grains are intimately intergrown, show no clear evidence for 39 Ar recoil depletion in the K-rich phases. The difference is resolvable if illite argon release is not a simple volume diffusion type process under vacuum conditions. (author)

  7. Existência e inexistência de cercamento, segurança e acessibilidade de parques urbanos

    Directory of Open Access Journals (Sweden)

    Arq. Débora Gregoletto

    2013-07-01

    Full Text Available Este trabalho tem como objetivo avaliar a influência da presença ou ausência de cercamento de parques públicos urbanos na percepção dos usuários em relação a segurança dos usuários (do interior e exterior dos parques e do patrimônio público, bem como na acessibilidade desses espaços e os efeitos causados por este no uso e apropriação dos espaços internos dos parques. Para tanto, foram avaliados dois parques de Porto Alegre–RS, quais sejam o Parque Farroupilha e o Parque Germânia. Os principais resultados evidenciam que a percepção de segurança não é influenciada pela falta de cercamento em parques abertos, ao contrário do que ocorre em parques fechados. Os usuários de parques fechados associam a presença de cercamento na preservação do patrimônio público, sendo que em parques abertos essa avaliação varia em relação ao tipo de usuário. Além disso, os tipos de atividades realizadas pelos usuários de parques abertos, assim como a proximidade da residência, tanto em parques fechados como em abertos, são fatores que influenciam na avaliação de acessibilidade de parques urbanos.

  8. Influence of residual Ar+ in Ar cluster ion beam for DLC film formation

    International Nuclear Information System (INIS)

    Kitagawa, Teruyuki; Miyauchi, Kazuya; Toyoda, Noriaki; Kanda, Kazuhiro; Ikeda, Tokumi; Tsubakino, Harushige; Matsuo, Jiro; Matsui, Shinji; Yamada, Isao

    2003-01-01

    In order to study the influences of residual Ar monomer ion (Ar + ) on sp 2 content and hardness of diamond like carbon (DLC) films formed by Ar cluster ion beam assisted deposition, Ar cluster ion, Ar + and their mixed ions (Ar cluster ion and Ar + ) bombardments were performed during evaporation of C 60 . From near edge X-ray absorption fine structure (NEXAFS) and Raman spectroscopy measurements, lower sp 2 content in the carbon films was obtained with Ar cluster ion bombardment than that with Ar + and mixed ion. Furthermore higher hardness and smooth surface were shown with Ar cluster ion bombardments. Therefore it was important to reduce Ar + in Ar cluster ion beams to obtain hard DLC films with flat surface

  9. Effects of shock pressure on 40Ar-39Ar radiometric age determinations

    International Nuclear Information System (INIS)

    Davis, P.K.

    1977-01-01

    The relation of shock to the drop in the 40 *Ar/ 39 *Ar ratio seen at high release temperatures in some neutron-irradiated lunar samples is investigated through measurements of the 40 *Ar/ 39 *Ar ratio in gas samples released by stepwise heating of rock samples previously subjected to shock, either in the laboratory or in nature. Explosives were used to shock solid pieces and powder of a basalt from a diabase dike in Liberia to calculated pressures of 65, 150 and 270 kbar. These, an unshocked sample of the powder, two naturally shocked samples from the Brent impact crater in Canada, one unshocked sample from near the crater, and appropriate monitors were irradiated. Ar from stepwise heating was analyzed. The unshocked basalt shows a good 40 *Ar/ 39 *Ar plateau at age 198 +-9 m.y. in agreement with a previous result of 186 +- 2 m.y. The shocked samples contain varying amounts of implanted atmospheric Ar, the isotopes of which have experienced mass fractionation. This effect is small enough in four samples so that the linearity of their graphs of 39 *Ar/ 40 Ar vs 36 Ar/ 40 Ar is evidence of a plateau. The ages of these samples are then 201 +- 10, 205 +- 12 and 201 +-9 m.y. It appears that the shock has had little effect on the 40 Ar- 39 Ar age spectrum, although the release patterns of the 39 *Ar are shifted downward by the order of 200 0 C. Shock implantation of Ar was at lower shock pressure, in the presence of less Ar, and into a less porous material than previously demonstrated. The Brent Crater samples do not all show good plateaus, but do indicate an age of 420 m.y. for the crater event and 795 +- 24 m.y. for the rock formation, in agreement with previous results. None of the 40 *Ar/ 39 *Ar profiles shows a drop at high temperature, but a possible role of shock implantation of Ar is indicated in the production of this effect. Further experiments are suggested. (author)

  10. Electron scattering from 36Ar and 40Ar

    International Nuclear Information System (INIS)

    Finn, J.M.

    1975-01-01

    The argon isotopes, 36 Ar and 40 Ar, have been investigated using electron scattering at the high-resolution Linac facilities of the National Bureau of Standards. Both elastic scattering and scattering to low-lying states have been observed. A high-pressure, low-volume gas target cell was designed and developed for this experiment. The cell features a transmission geometry and has resolution comparable to solid targets. Spectra were obtained at incident beam energies ranging from 65 to 115 MeV at scattering angles of 92.5 0 and 110 0 . Values obtained for the rms charge radii are 3.327 +- 0.015 and 3.393 +- 0.015 fm for 36 Ar and 40 Ar respectively. A sensitive measurement was made of the difference in the two radii yielding a value of Δ r = 0.079 +- 0.006 fm. The inelastic levels observed are the 1.97 (2 + ) and 4.18 MeV (3 - ) levels in 36 Ar, and the 1.46 (2 + ), 2.52 (2 + ), 3.21 (2 + ), and 3.68 MeV (3 - ) levels in 40 Ar. A Tassie model analysis was made of the inelastic transitions in the DWBA approximation and transition strengths of these levels were extracted

  11. Baicalein suppresses the androgen receptor (AR)-mediated prostate cancer progression via inhibiting the AR N-C dimerization and AR-coactivators interaction.

    Science.gov (United States)

    Xu, Defeng; Chen, Qiulu; Liu, Yalin; Wen, Xingqiao

    2017-12-01

    Androgen receptor (AR) plays a critical role in prostate cancer (PCa) development and progression. Androgen deprivation therapy with antiandrogens to reduce androgen biosynthesis or prevent androgens from binding to AR are widely used to suppress AR-mediated PCa growth. However, most of ADT may eventually fail with development of the castration resistance after 12-24 months. Here we found that a natural product baicalein can effectively suppress the PCa progression via targeting the androgen-induced AR transactivation with little effect to AR protein expression. PCa cells including LNCaP, CWR22Rv1, C4-2, PC-3, and DU145, were treated with baicalein and luciferase assay was used to evaluate their effect on the AR transactivation. Cell growth and IC 50 were determined by MTT assay after 48 hrs treatment. RT-PCR was used to evaluate the mRNA levels of AR target genes including PSA, TMPRSS2, and TMEPA1. Western blot was used to determine AR and PSA protein expression. The natural product of baicalein can selectively inhibit AR transactivation with little effect on the other nuclear receptors, including ERα, and GR. At a low concentration, 2.5 μM of baicalein effectively suppresses the growth of AR-positive PCa cells, and has little effect on AR-negative PCa cells. Mechanism dissection suggest that baicalein can suppress AR target genes (PSA, TMPRSS2, and TMEPA1) expression in both androgen responsive LNCaP cells and castration resistant CWR22Rv1 cells, that may involve the inhibiting the AR N/C dimerization and AR-coactivators interaction. Baicalein may be developed as an effective anti-AR therapy via its ability to inhibit AR transactivation and AR-mediated PCa cell growth.

  12. Condicionamento de ar em salas de operação e controle de infecção - uma revisão

    Directory of Open Access Journals (Sweden)

    May Socorro Martinez Afonso

    2006-04-01

    Full Text Available Revisão bibliográfica, realizada junto aos bancos de dados MED LINE, LILACS, SCIELO, Ministério da Saúde e outros buscadores, com o objetivo de identificar os fatores que torna o ar condicionado fonte de contaminação ambiental. O ar é contaminado por partículas que transportam microrganismos. As fontes de partículas incluem pacientes e equipe cirúrgica. O controle da temperatura, umidade relativa, pressão, número de trocas de ar realizadas por hora, paramentação, tráfego, número de pessoas nas salas e manutenção e limpeza do sistema de ar condicionado dos centros cirúrgicos, são fatores importantes na redução do número de microrganismos no ambiente de sala de operação.

  13. O letramento e a organização da informação digital aliados ao aprendizado ao longo da vida

    Directory of Open Access Journals (Sweden)

    Sonia Boeres

    2018-03-01

    Full Text Available O letramento digital é fruto de pensamento crítico e busca potencializar os métodos de estudo pela tecnologia da informação. A questão de pesquisa aqui tratada é compreender como o letramento digital pode contribuir para o aprendizado ao longo da vida. O objetivo é traçar um paralelo entre o letramento e a informação digital e o aprendizado ao longo da vida. Como metodologia fez-se uma revisão de literatura, nacional e internacional, sobre o processo de ensino e aprendizagem, letramento informacional, digital e aprendizado ao longo da vida. Esta pesquisa é de natureza descritiva e base qualitativa. Os principais resultados observados foram que o letramento digital leva a variadas práticas de leitura e escrita por meio das tecnologias da informação. Estas trazem novas possibilidades para educadores e educandos, profissionais e usuários, transcendendo o simples ato de decodificar sinais ou pesquisar na Internet. Ser letrado digitalmente leva à compreensão de que a tecnologia da informação vai além de novas formas de acesso à informação, mas também a novos processos cognitivos e formas de conhecimento. Chegando-se a esse patamar, cabe o árduo e prazeroso trabalho de manter-se atualizado ao longo do tempo, por meio de um esforço pessoal, que envolvem cursos e treinamentos como fonte de aprendizagem e desenvolvimento de trabalho em conjunto com especialistas. Em suma, há que se manter atualizado, acompanhando a evolução tecnológica, e para tanto, ser destemido das tecnologias e do uso das mídias digitais.

  14. /sup 40/Ar//sup 39/Ar and K-Ar dating of altered glassy volcanic rocks: the Dabi Volcanics, P. N. G

    Energy Technology Data Exchange (ETDEWEB)

    Walker, D.A. (Australian National Univ., Canberra. Dept. of Geology); McDougall, I. (Australian National Univ., Canberra. Research School of Earth Sciences)

    1982-11-01

    K-Ar and /sup 40/Ar//sup 39/Ar ages have been determined for altered submarine tholeiitic and boninite (high-Mg andesite) lavas from the Dabi Volcanics, Cape Vogel Peninsula, Papua New Guinea. /sup 40/Ar//sup 39/Ar whole rock total fusion and plateau ages identify a Late Paleocene age for the tholeiitic lavas (58.9 +- 1.1 Ma), and also for the boninitic lavas (58.8 +- 0.8 Ma). Apparent K-Ar ages for the same samples range from 27.2 +- 0.7 to 63.9 +- 4.5 Ma, and young K-Ar ages for glassy boninites are probably due to variable radiogenic /sup 40/Ar(/sup 40/Ar*) loss. These new ages effectively reconcile previously ambiguous age data for the Dabi Volcanics, and indicate contemporaneous tholeiitic and boninitic volcanism occurring in southeast PNG during the Late Paleocene. Smectites, developed as alteration products after glass in oceanic lavas commonly do not retain /sup 39/Ar during or subsequent to irradiation, but in some cases may contain /sup 40/Ar*. The results are discussed.

  15. Cartografar é traçar um plano comum

    Directory of Open Access Journals (Sweden)

    Virgínia Kastrup

    2013-08-01

    Full Text Available A pesquisa de campo sobre produção da subjetividade enfrenta o problema de construir conhecimento envolvendo pesquisadores e pesquisados, com territórios e semióticas singulares. Surgem questões relativas ao protagonismo dos participantes e a como traçar com eles um plano comum, garantindo o caráter participativo da pesquisa. No contexto do método da cartografia, o artigo tem como objetivo tratar do tema do comum num duplo aspecto. Num primeiro, discute o acesso ao plano comum. Com base em Gilles Deleuze e Felix Guattari, tal plano não é dito homogêneo nem reúne atores que manteriam entre si relações de identidade, mas opera comunicação entre singularidades, sendo pré-individual e coletivo. Num segundo aspecto, aponta que, enquanto pesquisa-intervenção, a cartografia se compromete com a criação de um mundo comum e heterogêneo. O artigo mostra que o traçado do comum tem como diretriz metodológica a tranversalidade e examina os procedimentos de participação, inclusão e tradução.

  16. Single electron capture by state-prepared Ar2+ projectiles in Ar

    International Nuclear Information System (INIS)

    Puerta, J.; Huber, B.A.

    1985-03-01

    Electron capture by state-selected Ar 2+ projectiles in Ar has been studied at low collision energies ( 2+ ions are measured explaining existing discrepancies of partial and total cross sections in the Ar 2+ /Ar collision system. Although highly excited metastable ions ( 5 D 4 0 , 3 F 4 0 ) represent a minor contamination of a non-prepared Ar 2+ beam (proportional1%), their contributions are found to dominate the capture process due to cross section values larger than 10 -15 cm 2 . (orig.)

  17. A radiation-electric-field combination principle for SO2-oxidation in Ar-mixtures

    International Nuclear Information System (INIS)

    Leonhardt, J.; Krueger, H.; Popp, P.; Boes, J.

    1981-01-01

    A simple model for a radiation-induced SO 2 -oxidation in Ar using SO 2 /O 2 /Ar-mixtures has been described by Leonhardt a.o. It is possible to improve the efficiency of the radiation-induced SO 2 -oxidation in such mixtures if the electrons produced by the ionizing radiation are accelerated by means of an electric field. The energy of the field-accelerated electrons must be high enough to form reactive SO 2 radicals but not high enough to ionize the gas mixture. Such an arrangement is described. The connection between the rate of SO 3 -formation and the electric field and the connection between SO 3 -formation and decreasing of the O 2 -concentration in the reaction chaimber were experimentally determined. Further the G-values attained by means of the radiation-electric-field combination are discussed. (author)

  18. AoS28D, a proline-Xaa carboxypeptidase secreted by Aspergillus oryzae.

    Science.gov (United States)

    Salamin, Karine; Eugster, Philippe J; Jousson, Olivier; Waridel, Patrice; Grouzmann, Eric; Monod, Michel

    2017-05-01

    Prolyl peptidases of the MEROPS S28 family are of particular interest because they are key enzymes in the digestion of proline-rich peptides. A BLAST analysis of the Aspergillus oryzae genome revealed sequences coding for four proteases of the S28 family. Three of these proteases, AoS28A, AoS28B, and AoS28C, were previously characterized as acidic prolyl endopeptidases. The fourth protease, AoS28D, showed high sequence divergence with other S28 proteases and belongs to a phylogenetically distinct cluster together with orthologous proteases from other Aspergillus species. The objective of the present paper was to characterize AoS28D protease in terms of substrate specificity and activity. AoS28D produced by gene overexpression in A. oryzae and in Pichia pastoris was a 70-kDa glycoprotein with a 10-kDa sugar moiety. In contrast with other S28 proteases, AoS28D did not hydrolyze internal Pro-Xaa bonds of several tested peptides. Similarly, to human lysosomal Pro-Xaa carboxypeptidase, AoS28D demonstrated selectivity for cleaving C-terminal Pro-Xaa bonds which are resistant to carboxypeptidases of the S10 family concomitantly secreted by A. oryzae. Therefore, AoS28D could act in synergy with these enzymes during sequential degradation of a peptide from its C-terminus.

  19. On mechanism of Ar(3p54p) states excitation in low-energy Ar-Ar collisions

    International Nuclear Information System (INIS)

    Kurskov, S Y; Kashuba, A S

    2009-01-01

    The present work is devoted to study of Ar(3p 5 4p) states excitation in binary low-energy Ar-Ar collisions. The results of the experimental investigation of excitation cross sections of Ar I 4p'[l/2] 1 , 4p'[3/2] 1 , 4p'[3/2] 2 and 4p[3/2] 2 levels in the collision energy range from threshold up to 500 eV (cm) and degree of polarization for 4s[3/2] 2 0 -4p'[l/2] 1 and 4s[3/2] 2 0 -4p[3/2] 2 transitions in this energy range are represented.

  20. First-principles calibration of 40Ar/39Ar mineral standards and complete extraction of 40Ar* from sanidine

    Science.gov (United States)

    Morgan, L. E.; Kuiper, K.; Mark, D.; Postma, O.; Villa, I. M.; Wijbrans, J. R.

    2010-12-01

    40Ar/39Ar geochronology relies on comparing argon isotopic data for unknowns to those for knowns. Mineral standards used as neutron fluence monitors must be dated by the K-Ar method (or at least referenced to a mineral of known K-Ar age). The commonly used age of 28.02 ± 0.28 Ma for the Fish Canyon sanidine (FCs) (Renne et al., 1998) is based upon measurements of radiogenic 40Ar in GA1550 biotite (McDougall and Roksandic, 1974), but underlying full data were not published (these measurements were never intended for use as an international standard), so uncertainties are difficult to assess. Recent developments by Kuiper et al. (2008) and Renne et al. (2010) are limited by their reliance on the accuracy of other systems. Modern technology should allow for more precise and accurate calibration of primary K-Ar and 40Ar/39Ar standards. From the ideal gas law, the number of moles of 40Ar in a system can be calculated from measurements of pressure, volume, and temperature. Thus we have designed and are proceeding to build a pipette system to introduce well-determined amounts of 40Ar into noble gas extraction lines and mass spectrometers. This system relies on components with calibrations traceable to SI unit prototypes, including a diaphragm pressure gauge (MKS Instruments), thermocouples, and a “slug” of an accurately determined volume to be inserted into the reservoir for volume determinations of the reservoir and pipette. The system will be renewable, with a lifetime of ca. 1 month for gas in the reservoir, and portable, to permit interlaboratory calibrations. The quantitative extraction of 40Ar* from the mineral standard is of highest importance; for sanidine standards this is complicated by high melt viscosity during heating. Experiments adding basaltic “zero age glass” (ZAG) to decrease melt viscosity are underway. This has previously been explored by McDowell (1983) with a resistance furnace, but has not been quantitatively addressed with laser heating

  1. Structural, K-Ar and 40Ar-39Ar age studies of adularia K-feldspars from the Lizard Complex, England

    International Nuclear Information System (INIS)

    Halliday, A.N.; Mitchell, J.G.

    1976-01-01

    Conventional K-Ar analyses of fifteen adularia feldspars from the Lizard Complex yield ages between 181+-2 Ma and 220+-3 Ma (with one exception from Holseer Cove yielding an age of 156+-3 Ma). The feldspars are dominantly monoclinic but most contain a minor but constant proportion of triclinic material with variable triclinicity. An inverse correlation exists between triclinicity and K-Ar age interpreted as representing argon loss related to the structural state. Extrapolation of the data to zero triclinicity indicates a true age of 210-220 Ma. 40 Ar- 39 Ar stepwise degassing analyses yield plateau ages related to the K-Ar ages and not the crystallization age. The results can be explained in terms of postcrystallization Al-Si ordering resulting in argon loss from lattice sites which under normal diffusion conditions requires a range of activation energies. The Holseer Cove sample is monoclinic and an 40 Ar- 39 Ar stepheating analysis suggests a later crystallization at 160-170 Ma. Neither primary crystallization nor spontaneous ordering through time explain the origin of the triclinic adularia. It is suggested that ordering has been induced by the passage of low-temperature alkaline solutions at a subsequent point in geological time. Argon loss by ordering could explain the low ages found using both K-Ar and 40 Ar- 39 Ar stepheating methods when applied to feldspars in general. The 210-220 Ma, and 160-170 Ma hydrothermal events affected much of southwest England and are probably related to major geotectonic movements in western Europe. (Auth.)

  2. The free/open source software movement: resistance or change? = O movimento de software livre/aberto: resistência ou mudança?

    OpenAIRE

    Georgopoulou, Panayiota

    2009-01-01

    Num momento em que as empresas privadas estão inventando modos de "bloqueio de informação" e em que governos neo-liberais estão impondo sanções severas para aqueles que violam os direitos de propriedade intelectual, o Movimento de Software Liver/Aberto foi contra o neo-liberalismo e a privatização generalizada: o movimento desafia regulações de propriedade em uma área-chave de crescimento das sociedades capitalistas contemporâneas, a saber, a construção e utilização de informações. No final d...

  3. Geochronology and thermochronology by the 40Ar/39Ar method

    International Nuclear Information System (INIS)

    McDougall, I.; Harrison, T.M.

    1988-01-01

    This work is a response to the authors' belief that there is a need for a monograph on 40 Ar/ 39 Ar dating to provide concise knowledge concerning the application of this method to geological studies. They aim to provide a reasonably comprehensive but by no means exhaustive coverage of the principles and practices of 40 Ar/ 39 Ar dating, with emphasis on interpretation of results. In attempting to provide an overview of the current state of knowledge, they commonly cite examples from the available literature. They draw rather heavily upon their own work, because they feel comfortable with their own examples. (author)

  4. A flavor of 40Ar-39Ar geochronology research at lIT Bombay

    International Nuclear Information System (INIS)

    Pande, Kanchan

    2017-01-01

    Geochronology based on radiogenic isotopes has become an invaluable tool in earth sciences. Several radioactive parent-daughter systems of varying half-lives such as Rb-Sr, Sm-Nd, K-Ar have been traditionally used by researchers for determining the timing of geological and planetary processes. 40 Ar- 39 Ar dating, a variant of the K-Ar system, is a well-established and versatile method of determining the eruptive ages of volcanic rocks and the ∼150-500° C thermal histories of a variety of more slowly cooled igneous and metamorphic rocks. In the 40 Ar- 39 Ar method the sample is irradiated by fast neutrons in a nuclear reactor to convert some of 39 K into 39 Ar. The fixed natural ratio 39 K/ 40 K provides estimate for the parent 40 K by measuring 39 Ar. In order to know the conversion factor of 39 K to 39 Ar and to take care of other nuclear interfering reactions a sample of known K-Ar age is irradiated along with the unknown. The age of the unknown is then derived by comparison with the monitor sample of known age

  5. Vector analyzing power and cross section for the reactions 40Ar(d(pol),p)41Ar and 40Ar(d(pol),t)39Ar

    International Nuclear Information System (INIS)

    Sen, S.; Darden, S.E.; Yoh, W.A.; Berners, E.D.

    1975-01-01

    Angular distributions of vector analyzing power and cross section for the reactions 40 Ar(d,p) 41 Ar and 40 Ar(d,t) 39 Ar have been measured at an incident deuteron energy of 14.83 MeV. The bound-state data in the (d,p) reaction and the (d,t) data are compared to DWBA calculations. The data for the neutron-unbound states are analyzed in the framework of the DWBA using (i) a form factor for weakly bound neutron and (ii) a resonance form factor, following the approach of Vincent and Fortune. The j-dependence of the (d,p) vector analyzing power permits definite spin-parity assignments to be made for 19 neutron-bound and 4 neutron unbound states in 41 Ar with excitation energy up to 6.57 MeV. Tentative Jsup(π) assignments have been made for 3 states. The l-value for the 5.62 MeV states has been determined. Data for the observed unbound states are found to be equally well reproduced by the type (i) calculations as by the type (ii) calculations. The (d,t) vector cnalyzing power data show definite J-dependence although not as strongly as in the (d,p) reaction. For relatively weakly excited states a pre-knowledge of the l-value of the transition is desirable for an unambiguous spin assignment. In general, the J-dependence in the (d,t) vector analyzing power can be utilized for definitive Jsup(π) assignments. On this basis, Jsub(π) values have been assigned for seven states in 39 Ar with excitation energies up to 4.47MeV excitation. Possible spin values for three other states are suggested. Spectroscopic factors fo the states in 41 Ar and 39 Ar have been extracted and are in fair agreement with those obtained by other workers. (Auth.)

  6. Spectroscopic analysis of visible and near UV light emitted by Ar7+ and Ar6+ ions produced in Ar8+-He and Ar8+-H2 collisions at 120 keV

    International Nuclear Information System (INIS)

    Boduch, P.; Chantepie, M.; Hennecart, D.; Husson, X.; Kucal, H.; Lecler, D.; Stolterfoht, N.; Druetta, M.; Fawcett, B.; Wilson, M.

    1992-01-01

    A spectroscopic analysis of light emitted in the 2000-6000A wavelength range by Ar 7+ and Ar 6+ ions produced in Ar 8+ -He and Ar 8+ -H 2 collisions at 120 keV is performed. Well resolved fine structure components of 5s-5p and 5p-5d transitions in Ar VIII following single electron capture are precisely measured. Predominant lines due to double electron capture are observed. In particular, strong lines observed both in Ar 8+ -He and Ar 8+ -H 2 collisions are attributed to Ryberg transitions 3snl-3sn'l' in Ar VII. Attempts at identifications are made for the transition 3dnl-3dn'l' (n=4, 5) with the help of ab initio calculations. Photon emission cross sections for individual lines are determined from the measured data. (orig.)

  7. Construção de um catálogo de aglomerados abertos para estudo da dinâmica da estrutura espiral da Galáxia

    Science.gov (United States)

    Carlos, I. M.; Lépine, J. R. D.

    2003-08-01

    Os aglomerados abertos são objetos de grande valor para o estudo da dinâmica da Galáxia devido esses objetos terem uma faixa de idade relativamente ampla. O trabalho visa estudar a dinâmica da estrutura espiral da Galáxia principalmente através do uso desses aglomerados, uma vez que o estudo da cinemática desses objetos é fundamental para esse objetivo. Nosso grupo trabalha no sentido de construir uma base de dados de aglomerados abertos contendo coordenadas, distância, idade, movimentos próprios e velocidades radiais e já disponibiliza uma nova versão do catálogo de aglomerados abertos o qual é uma compilação de edições anteriores, principalmente Lynga (1987), Mermilliod (1995) e ESO-B (Lauberts 1982). Nossa amostra possui cerca de 1630 aglomerados, mas nem todos os parâmetros acima citados foram determinados em sua totalidade. Para determinarmos esses parâmetros, derivamos as cores intrínsecas das estrelas membro de cada aglomerado a partir de seus tipos espectrais (busca feita no SIMBAD) obtendo assim o excesso de cor individual. A distribuição dos excessos de cor foi então utilizada para derivarmos o avermelhamento médio para cada aglomerado. De maneira similar, os tipos espectrais foram usados para estimar as magnitudes absolutas, e com as magnitudes absolutas e aparentes determinamos a respectiva distribuição do módulo de distância e finalmente a distância. Para determinar as idades foram confeccionados os diagramas cor-magnitude das estrelas de cada aglomerado onde foram superpostas a Seqüência Principal de Idade Zero (ZAMS). Superpomos a ZAMS de Schmidt-Kaler e isócronas de composição solar. Essas isócronas foram usadas para determinação das idades dos aglomerados. Uma vez que não temos ainda resultados finais, apresentamos então alguns diagramas cor-magnitude os quais foram usados para determinação, principalmente, da distância e idade dos aglomerados.

  8. 40Ar/39Ar dating of pyrite

    International Nuclear Information System (INIS)

    York, D.; Masliwec, A.; Kuybida, P.; Hanes, J.A.; Hall, C.M.; Kenyon, W.J.; Spooner, E.T.C.; Scott, S.D.

    1982-01-01

    To overcome difficulties encountered in the customary method of determining the age of mineralization of sulphide ore deposits by analysing silicate material, the sulphide minerals themselves have been examined to see if they contained sufficient potassium and argon for 40 Ar/ 39 Ar age determination. Initial results indicate that this is the case for pyrite from the Geco ore body in northwestern Ontario, Canada. (U.K.)

  9. Ar-40/Ar-39 Studies of Martian Meteorite RBT 04262 and Terrestrial Standards

    Science.gov (United States)

    Park, J.; Herzog, G. F.; Turrin, B.; Lindsay, F. N.; Delaney, J. S.; Swisher, C. C., III; Nagao, K.; Nyquist, L. E.

    2014-01-01

    Park et al. recently presented an Ar-40/Ar-39 dating study of maskelynite separated from the Martian meteorite RBT 04262. Here we report an additional study of Ar-40/Ar-39 patterns for smaller samples, each consisting of only a few maskelynite grains. Considered as a material for Ar-40/Ar-39 dating, the shock-produced glass maskelynite has both an important strength (relatively high K concentration compared to other mineral phases) and some potentially problematic weaknesses. At Rutgers, we have been analyzing small grains consisting of a single phase to explore local effects that might be averaged and remain hidden in larger samples. Thus, to assess the homogeneity of the RBT maskelynite and for comparison with the results of, we analyzed six approx. 30 microgram samples of the same maskelynite separate they studied. Furthermore, because most Ar-40/Ar-39 are calculated relative to the age of a standard, we present new Ar-40/Ar-39 age data for six standards. Among the most widely used standards are sanidine from Fish Canyon (FCs) and various hornblendes (hb3gr, MMhb-1, NL- 25), which are taken as primary standards because their ages have been determined by independent, direct measurements of K and A-40.

  10. Desnudar e dançar, a pesar de... [Clarice Lispector e Pina Bausch

    Directory of Open Access Journals (Sweden)

    Eleonora Frenkel

    2013-07-01

    Full Text Available O texto propõe pensar a escritura de Clarice Lispector como a condução de um corpo-linguagem que quer se espaçar como o corpo do dançarino: livre de qualquer determinação exterior. Uma escrita que se desloca evadindo as figurações e a fixidez do discurso condutor de sentido. O desafio está em sair das normativas da linguagem com ela mesma, criando no espaço da literatura uma suspensão de suas leis. No contato da literatura com a música e a dança, trata-se de fazer ressoar a palavra, fazê-la vibrar como no improviso do jazz, aberta ao erro e aos desvios da harmonia, e de conduzi-la no deslocamento de uma dança, livre do ordenamento sintático de seus passos.

  11. 37Ar and 39Ar in meteorites and the spatial cosmic ray gradient

    International Nuclear Information System (INIS)

    Heusser, G.; Schaeffer, O.A.

    1977-01-01

    Cosmic-ray-produced 37 Ar (tsub(1/2) = 35 days), and 39 Ar (tsub(1/2) = 269 years) in the Fe-Ni phase of meteorites have been studied in connection with their implications for the radial gradient of cosmic ray particles. For the chondrite, Canon City, which fell on October 27, 1973, 20.1 +- 1.5 dpm/kg FeNi of 37 Ar and 22.5 +- 1.4 dpm/kg FeNi of 39 Ar was found. Usually, the 37 Ar/ 39 Ar ratio is used to deduce a spatial gradient. However, 37 Ar data reported in the literature are inconsistent. They fluctuate much more than could be accounted for by different orbits and the anticipated correlation with the cosmic ray neutron registrations is rather weak. Consequently, the 37 Ar/ 39 Ar-derived gradient has a low confidence level. On the other hand, 39 Ar activities group close to a mean value of 22.5 dpm/kg FeNi and appear to be almost independent of the different meteoroid orbits. A comparison of measured 39 Ar activities in meteorites with those calculated for orbits obtained from fireball data shows that a gradient of 10%/Au or less is reconcilable with the experimental findings. The average gradient (E > 200 MeV) during the last 500 years was probably not much larger than that measured presently by the Pioneer 10 and 11, and Helios spacecrafts. (Auth.)

  12. Photoionization study of HgAr

    International Nuclear Information System (INIS)

    Linn, S.H.; Brom, J.M. Jr.; Tzeng, W.; Ng, C.Y.

    1985-01-01

    Photoionization efficiency data for HgAr + have been obtained in the region of 680--1240 A. The ionization energy of HgAr was determined to be 10.217 +- 0.012 eV. This value allows the calculation of the dissociation energy of HgAr + to be 0.228 +- 0.017 eV. The relative probabilities for the formation of HgAr + via the reactions Ar* x Hg or Hg* x Ar→ HgAr + +e - with Ar* and Hg* prepared in high Rydberg states in the energy range of 10.22--15.79 eV were estimated. Although the radii for the 3d and 5s Rydberg ortitals of Ar have similar values, the probabilities for the formation of HgAr + from Hg x Ar* with Ar* in the 5s[3/2] 0 1 and 5s'[1/2] 0 1 Rydberg states are substantially greater than those when the Ar* excited atoms are in the 3d[1/2] 0 1 , 3s[3/2] 0 1 , and 3d'[3/2] 0 1 Rydberg levels. The ratio for the cross sections for the formation of HgAr + from Hg x Ar* with Ar* formed in the 3d[1/2] 0 1 and 4d[1/2] 0 1 states, as well as that with Ar* prepared in the 5d[1/2] 0 1 and 6d[1/2] 0 1 states, were found to be consistent with the predictions of the previous impact parameter calculations

  13. Age measurements of potassium-bearing sulfide minerals by the 40Ar/39Ar technique

    International Nuclear Information System (INIS)

    Czamanske, G.K.; Lanphere, M.A.; Erd, R.C.; Blake, M.C. Jr.

    1978-01-01

    K-Ar ages have been determined for sulfide minerals for the first time. The occurrence of adequate amounts of potassium-bearing sulfides with ideal compositions K 3 Fe 10 S 14 (approximately 10 wt.% K) and KFe 2 S 3 (approximately 16 wt.% K) in samples from a mafic alkalic diatreme at Coyote Peak, California, prompted an attempt to date these materials. K 3 Fe 10 S 14 , a massive mineral with conchoidal fracture, gives an age of 29.4 +- 0.5 m.y. ( 40 Ar/ 39 Ar), indistinguishable from the 28.3 +- 0.4 m.y. ( 40 Ar/ 39 Ar) and 30.2 +- 1.0 m.y. (conventional K-Ar) ages obtained for associated phlogopite (8.7 wt.% K). KFe 2 S 3 , a bladed, fibrous sulfide, gives a younger age, 26.5 +- 0.5 m.y. ( 40 Ar/ 39 Ar), presumably owing to Ar loss. (Auth.)

  14. Ar-Ar dating techniques for terrestrial meteorite impacts

    Science.gov (United States)

    Kelley, S. P.

    2003-04-01

    The ages of the largest (>100 km) known impacts on Earth are now well characterised. However the ages of many intermediate sized craters (20-100 km) are still poorly known, often the only constraints are stratigraphic - the difference between the target rock age and the age of crater filling sediments. The largest impacts result in significant melt bodies which cool to form igneous rocks and can be dated using conventional radiometric techniques. Smaller impacts give rise to thin bands of melted rock or melt clasts intimately mixed with country rock clasts in breccia deposits, and present much more of a challenge to dating. The Ar-Ar dating technique can address a wide variety of complex and heterogeneous samples associated with meteorite impacts and obtain reasonable ages. Ar-Ar results will be presented from a series of terrestrial meteorite impact craters including Boltysh (65.17±0.64 Ma, Strangways (646±42 Ma), and St Martin (220±32 Ma) and a Late Triassic spherule bed, possibly representing distal deposits from Manicouagan (214±1 Ma) crater. Samples from the Boltysh and Strangways craters demonstrate the importance of rapid cooling upon the retention of old ages in glassy impact rocks. A Late Triassic spherule bed in SW England is cemented by both carbonate and K-feldspar cements allowing Ar-Ar dating of fine grained cement to place a mimimum age upon the age of the associated impact. An age of 214.7±2.5 Ma places the deposit with errors of the age of the Manicouagan impact, raising the possibility that it may represent a distal deposit (the deposit lay around 2000 km away from the site of the Manicouagan crater during the Late Triassic). Finally the limits of the technique will be demonstrated using an attempt to date melt rocks from the St Martin Crater in Canada.

  15. ScattAR

    DEFF Research Database (Denmark)

    Baldwin, Alex Dempster; Serafin, Stefania; Erkut, Cumhur

    2017-01-01

    We present an augmented reality (AR) audio application where scattering delay networks efficiently generate and organize a reverberator, based on room geometry scanned by an AR device. The application allows for real-time processing and updating of reflection path geometry. It provides a proof...

  16. Ar-39/Ar-40 systematics of Allende inclusions

    International Nuclear Information System (INIS)

    Herzog, G.F.; Rutgers University, New Brunswick, NJ); Bence, A.E.

    1980-01-01

    A laser microprobe was used to measure the Ar isotopic contents of individual mineral grains in four neutron-irradiated Allende samples: two coarse-grained Ca-Al-rich inclusions, one fine-grained Ca-Al-rich inclusion, and one sample with matrix and miscellaneous chondrules. The following K-Ar ages (G.y.) were obtained after degassing low Ar retentive sites by preheating the samples for one hour at 675 C: matrix, 3.5 + or - 0.2 three miscellaneous chondrules, 4.4 + or - 0.1, 4.0 + or - 0.1, and 4.4 + or - 0.1 and the fine-grained inclusion, 4.5 + or - 0.2. The minerals in the coarse-grained Ca-Al-rich inclusions have ubiquitous chlorine, less than 10 ppm K and apparent ages ranging upwards from 4.6 G.y. to well over 10 G.y. Possible explanations for these apparent ages are atmospheric contamination, the decay of K-40 prior to the formation of the solar system, and the trapping of radiogenic Ar-40 lost by the matrix

  17. Métodos clássicos de protecção de sistemas elevatórios contra o golpe de aríete

    OpenAIRE

    Mendes, Luís Filipe Martins

    2011-01-01

    Dissertação para obtenção do Grau de Mestre em Engenharia do Ambiente, perfil Engenharia Sanitária A ocorrência de regimes transitórios, em particular do golpe de aríete e subsequente propagação de ondas de pressão, em sistemas elevatórios de água e águas residuais, é um acontecimento normal e frequente, que acompanha qualquer alteração nas suas condições normais de funcionamento. As circunstâncias mais violentas, associadas ao golpe de aríete, normalmente, resultam do corte de energia ...

  18. AR copy number and AR signaling-directed therapies in castration-resistant prostate cancer.

    Science.gov (United States)

    Salvi, Samanta; Conteduca, Vincenza; Lolli, Cristian; Testoni, Sara; Casadio, Valentina; Zaccheroni, Andrea; Rossi, Lorena; Burgio, Salvatore Luca; Menna, Cecilia; Schepisi, Giuseppe; De Giorgi, Ugo

    2017-11-22

    Adaptive upregulation of androgen receptor (AR) is the most common event involved in the progression from hormone sensitive to castration-resistant prostate cancer (CRPC). AR signaling remains the main target of new AR signalling-directed therapies such as abiraterone and enzalutamide in CRPC patients. In this review, we discuss general mechanisms of resistance to AR-targeted therapies, with a focus on the role of AR copy number (CN). We reported methods and clinical applications of AR CN evaluation in tissue and liquid biopsy, thus to have a complete information regarding its role as predictive and prognostic biomarker. Outcomes of CRPC patients are reported to be highly variable as consequence of tumor heterogeneity. AR CN could contribute to patient selection and tumor monitoring in CRPC treated with new anti-cancer treatment as abiraterone and enzalutamide. Further studies to investigate AR CN effect to these agents and its potential combination with other prognostic or predictive clinical factors are necessary in the context of harmonized clinical trial design. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  19. AR4VI: AR as an Accessibility Tool for People with Visual Impairments.

    Science.gov (United States)

    Coughlan, James M; Miele, Joshua

    2017-10-01

    Although AR technology has been largely dominated by visual media, a number of AR tools using both visual and auditory feedback have been developed specifically to assist people with low vision or blindness - an application domain that we term Augmented Reality for Visual Impairment (AR4VI). We describe two AR4VI tools developed at Smith-Kettlewell, as well as a number of pre-existing examples. We emphasize that AR4VI is a powerful tool with the potential to remove or significantly reduce a range of accessibility barriers. Rather than being restricted to use by people with visual impairments, AR4VI is a compelling universal design approach offering benefits for mainstream applications as well.

  20. 40Ar/39Ar age spectra from the KBS Tuff, Koobi Fora Formation

    International Nuclear Information System (INIS)

    McDougall, I.

    1981-01-01

    40 Ar/ 39 Ar age spectra on anorthoclase phenocrysts from three pumice clasts in the KBS Tuff yield nearly ideal flat patterns, providing good evidence that the samples have remained undisturbed since crystallization. The ages are concordant at 1.88 = 0.02 Myr, and confirm that the KBS Tuff, a key marker bed in the Koobi Fora Formation, northern Kenya, is now very well dated. These results resolve the conflict between earlier 40 Ar/ 39 Ar and conventional K-Ar dating measurements on the KBS Tuff. (author)

  1. 40Ar/39Ar age spectra from the KBS Tuff, Koobi Fora Formation.

    Science.gov (United States)

    McDougall, Ian

    1981-11-12

    40 Ar/ 39 Ar age spectra on anorthoclase phenocrysts from three pumice clasts in the KBS Tuff yield nearly ideal flat patterns, providing good evidence that the samples have remained undisturbed since crystallization. The ages are concordant at 1.88±0.02 Myr, and confirm that the KBS Tuff, a key marker bed in the Koobi Fora Formation, northern Kenya, is now very well dated. These results resolve the conflict between earlier 40 Ar/ 39 Ar and conventional K-Ar dating measurements on the KBS Tuff.

  2. MonitAR, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to develop MonitAR, an Augmented Reality (AR) system that provides procedure completion guidance to astronauts. MonitAR will replace guidance from mission...

  3. The 40Ar/39Ar and K/Ar dating of lavas from the Hilo 1-km core hole, Hawaii Scientific Drilling Project

    Science.gov (United States)

    Sharp, W.D.; Turrin, B.D.; Renne, P.R.; Lanphere, M.A.

    1996-01-01

    Mauna Kea lava flows cored in the HilIo hole range in age from <200 ka to about 400 ka based on 40Ar/39Ar incremental heating and K-Ar analyses of 16 groundmass samples and one coexisting plagioclase. The lavas, all subaerially deposited, include a lower section consisting only of tholeiitic basalts and an upper section of interbedded alkalic, transitional tholeiitic, and tholeiitic basalts. The lower section has yielded predominantly complex, discordant 40Ar/39Ar age spectra that result from mobility of 40Ar and perhaps K, the presence of excess 40Ar, and redistribution of 39Ar by recoil. Comparison of K-Ar ages with 40Ar/39Ar integrated ages indicates that some of these samples have also lost 39Ar. Nevertheless, two plateau ages of 391 ?? 40 and 400 ?? 26 ka from deep in the hole, combined with data from the upper section, show that the tholeiitic section accumulated at an average rate of about 7 to 8 m/kyr and has an mean recurrence interval of 0.5 kyr/flow unit. Samples from the upper section yield relatively precise 40Ar/39Ar plateau and isotope correlation ages of 326 ?? 23, 241 ?? 5, 232 ?? 4, and 199 ?? 9 ka for depths of -415.7 m to -299.2 m. Within their uncertainty, these ages define a linear relationship with depth, with an average accumulation rate of 0.9 m/kyr and an average recurrence interval of 4.8 kyr/flow unit. The top of the Mauna Kea sequence at -280 m must be older than the plateau age of 132 ?? 32 ka, obtained for the basal Mauna Loa flow in the corehole. The upward decrease in lava accumulation rate is a consequence of the decreasing magma supply available to Mauna Kea as it rode the Pacific plate away from its magma source, the Hawaiian mantle plume. The age-depth relation in the core hole may be used to test and refine models that relate the growth of Mauna Kea to the thermal and compositional structure of the mantle plume.

  4. AR4VI: AR as an Accessibility Tool for People with Visual Impairments

    OpenAIRE

    Coughlan, James M.; Miele, Joshua

    2017-01-01

    Although AR technology has been largely dominated by visual media, a number of AR tools using both visual and auditory feedback have been developed specifically to assist people with low vision or blindness – an application domain that we term Augmented Reality for Visual Impairment (AR4VI). We describe two AR4VI tools developed at Smith-Kettlewell, as well as a number of pre-existing examples. We emphasize that AR4VI is a powerful tool with the potential to remove or significantly reduce a r...

  5. Reevaluation of the Solar Wind 36Ar/38Ar Ratio

    Science.gov (United States)

    Becker, R. H.; Schlutter, D. J.; Rider, P. E.; Pepin, R. O.

    1996-03-01

    The isotopic composition of solar wind (SW) argon is an important parameter in the modeling of the evolution of the terrestrial planet atmospheres. Anders and Grevesse assumed a 36Ar/38Ar ratio for SW of 5.31, essentially equal to that of air. Considerable evidence has since developed which indicates that this ratio is too low. Benkert et al. have reported their best estimate for the recent SW as 5.48 +/- 0.05, determined from measurements of lunar soil 71501. Based on Ar data obtained from surface oxidation of a metal separate from the Weston meteorite and from an uncontrolled etch of lunar sample 67701, reported by our group previously, we consider even this value to be too low. Since values of 5.75 to 5.85 were reported by Black for initial low temperature (fairly high SW 36Ar/38Ar ratio (in the range of ~5.6 to ~5.7), we decided to analyze Kapoeta for its light solar wind gases using the acid-etching techniques developed in our laboratory based on the CSSE procedure of Benkert et al.

  6. 40Ar/39Ar laser-probe dating of diamond inclusions from the Premier kimberlite

    International Nuclear Information System (INIS)

    Phillips, D.; Onstott, T.C.; Harris, J.W.; Strathclyde Univ., Glasgow

    1989-01-01

    Inclusions encapsulated by diamonds at the time of their formation provide a means for determining diamond crystallization ages and the chemistry of the surrounding upper mantle at that time. Sm-Nd studies of peridotitic inclusions, from Cretaceous-age kimberlites in southern Africa, suggest that the diamonds formed 3.3 Gyr ago. By contrast, eclogite-suite inclusions generally yield younger ages, sometimes approaching the time of kimberlite eruption. Here we report the results of 40 Ar/ 39 Ar laser-probe analyses of individual eclogitic clinopyroxene inclusions from Premier diamonds, which yield a mean age of 1,198±14 Myr. This age agrees well with Sm-Nd and 40 Ar/ 39 Ar analyses on similar Premier inclusions, and is indistinguishable from the inferred time of emplacement of the host kimberlite (1,150-1,230 Myr), which implies that diamond formation was essentially synchronous with kimberlite generation. The extrapolated non-radiogenic 40 Ar/ 36 Ar ratio of 334±102 is similar to the present-day atmospheric composition. This value is inconsistent with Sr and Nd isotopic signatures from Premier eclogite inclusions, which suggest a depleted mantle source ( 40 Ar/ 36 Ar>20,000). Pre-entrapment equilibration of the inclusions with an 36 Ar-rich fluid is the most probable explanation for the low non-radiogenic ( 40 Ar/ 36 Ar) composition. (author)

  7. Arsenic exposure assessment of children living in a lead mining area in Southeastern Brazil Avaliação da exposição de crianças ao arsênio em área de mineração de chumbo na Região Sudeste do Brasil

    Directory of Open Access Journals (Sweden)

    Alice Momoyo Sakuma

    2010-02-01

    Full Text Available Environmental contamination by arsenic compounds in the Ribeira River Valley, São Paulo, Brazil has already been observed. Lead mining and refining activities had been carried on since late colonial times and finished recently, at the end of 1995. The source of As in the region is known to be mainly from arsenopirite geological presence in the lead ore. Chronic exposure to arsenic compounds may cause peripheral vascular disorders, hyperpigmentation, hiperkeratosis and cancer of the skin, bladder, lung, liver and other internal organs. The purpose of this study was to assess children exposure to arsenic from environmental sources in the region. Urine samples from children between 7 to 14 years old were collected at the following localities: Cerro Azul (Paraná; urban areas of Ribeira (São Paulo and Adrianópolis (Paraná; Vila Mota neighborhood (rural area of Adrianópolis and Serra neighborhood (Iporanga, São Paulo, identified as groups 1, 2, 3 and 4, respectively. Group 1 was considered as non-exposed control group. Toxicologically relevant forms of As were determined by atomic absorption spectrometry with hydride generation system. The median values of urine arsenic levels obtained in groups 1, 2, 3 and 4 were respectively: 3.60, 6.30, 6.41 e 8.94μg/L.Contaminação ambiental por compostos de arsênio no Vale do Ribeira, São Paulo, Brasil, tem sido já observada. As atividades de mineração e refinamento do chumbo têm ocorrido desde a época colonial e foram encerradas recentemente, no final de 1995. A principal fonte de arsênio na região é arsenopirita que ocorre geologicamente no minério de chumbo. Exposição crônica aos compostos de arsênio podem causar desordens vasculares periféricas, hiperpigmentação, hiperqueratose, além de câncer de pele, bexiga, pulmão, fígado e outros órgãos. O objetivo do presente estudo foi avaliar a exposição de crianças ao arsênio proveniente de fontes ambientais na região. Amostras de

  8. Ars disyecta Ars disyecta

    Directory of Open Access Journals (Sweden)

    Alejandra Castillo

    2012-07-01

    Full Text Available Bajo la nominación Ars Disyecta se busca exponer el vínculo entre artes visuales, feminismo y metamorfosis. Las prácticas artísticas feministas aquí presentadas se proponen perturbar el espacio metafórico heredado de la diferencia sexual (pensemos, por ejemplo, en las palabras engendramiento, matriz, vida, compenetración o invaginamiento. En este sentido, la nominación Ars disyecta pone en escena un conjunto de prácticas e intervenciones que intentan interrumpir la matriz de la diferencia, desestabilizando lo femenino desde aquellas figuras que se resisten a la lógica de la totalidad y de un tiempo propio. Buscando seguir la huella de un arte disyecto es que interrogaré en este ensayo aquellas autorías feministas que en el arte contemporáneo trafican con las huellas del contagio, la mutación y la alteridad.This article aims to present the relation between visual arts, feminism I and metamorphosis. The feminist artistic practices portrayed in this article attempt to question categories inherited from the metaphor of sexual difference such as engendering, matrix and life. From this perspective, Ars disyecta will establish a set of artistic practices and interventions that intend to interrupt the proper idea of «feminine difference». Following this line of argument, I will discuss in this article a few contemporary feminist works of art that could be defined by words such as contagious, mutation and otherness.

  9. 40Ar-39Ar method for age estimation: principles, technique and application in orogenic regions

    International Nuclear Information System (INIS)

    Dalmejer, R.

    1984-01-01

    A variety of the K-Ar method for age estimation by 40 Ar/ 39 Ar recently developed is described. This method doesn't require direct analysis of potassium, its content is calculated as a function of 39 Ar, which is formed from 39 K under neutron activation. Errors resulted from interactions between potassium and calcium nuclei with neutrons are considered. The attention is paid to the technique of gradual heating, used in 40 Ar- 39 Ar method, and of obtaining age spectrum. Aplicabilities of isochronous diagram is discussed for the case of presence of excessive argon in a sample. Examples of 40 Ar- 39 Ar method application for dating events in orogenic regions are presented

  10. Evidence of interatomic Coulombic decay in ArKr after Ar 2p Auger decay

    International Nuclear Information System (INIS)

    Morishita, Y; Saito, N; Suzuki, I H; Fukuzawa, H; Liu, X-J; Sakai, K; Pruemper, G; Ueda, K; Iwayama, H; Nagaya, K; Yao, M; Kreidi, K; Schoeffler, M; Jahnke, T; Schoessler, S; Doerner, R; Weber, T; Harries, J; Tamenori, Y

    2008-01-01

    We have identified interatomic Coulombic decay (ICD) processes in the ArKr dimer following Ar 2p Auger decay, using momentum-resolved electron-ion-ion coincidence spectroscopy and simultaneously determining the kinetic energy of the ICD electron and the KER between Ar 2+ and Kr + . We find that the spin-conserved ICD processes in which Ar 2+ (3p -3 3d) 1 P and 3 P decay to Ar 2+ (3p -2 ) 1 D and 3 P, respectively, ionizing the Kr atom, are significantly stronger than the spin-flip ICD processes in which Ar 2+ (3p -3 3d) 1 P and 3 P decay to Ar 2+ (3p -2 ) 3 P and 1 D, respectively

  11. Feldspar 40Ar/39Ar dating of ICDP PALEOVAN cores

    Science.gov (United States)

    Engelhardt, Jonathan Franz; Sudo, Masafumi; Stockhecke, Mona; Oberhänsli, Roland

    2017-11-01

    Volcaniclastic fall deposits in ICDP drilling cores from Lake Van, Turkey, contain sodium-rich sanidine and calcium-rich anorthoclase, which both comprise a variety of textural zoning and inclusions. An age model records the lake's history and is based on climate-stratigraphic correlations, tephrostratigraphy, paleomagnetics, and earlier 40Ar/39Ar analyses (Stockhecke et al., 2014b). Results from total fusion and stepwise heating 40Ar/39Ar analyses presented in this study allow for the comparison of radiometric constraints from texturally diversified feldspar and the multi-proxy lacustrine age model and vice versa. This study has investigated several grain-size fractions of feldspar from 13 volcaniclastic units. The feldspars show textural features that are visible in cathodoluminescence (CL) or back-scattered electron (BSE) images and can be subdivided into three dominant zoning-types: (1) compositional zoning, (2) round pseudo-oscillatory zoning and (3) resorbed and patchy zoning (Ginibre et al., 2004). Round pseudo-oscillatory zoning records a sensitive alternation of Fe and Ca that also reflects resorption processes. This is only visible in CL images. Compositional zoning reflects anticorrelated anorthite and orthoclase contents and is visible in BSE. Eleven inverse isochron ages from total fusion and three from stepwise heating analyses fit the age model. Four experiments resulted in older inverse isochron ages that do not concur with the model within 2σ uncertainties and that deviate from 1 ka to 17 ka minimum. C- and R-type zoning are interpreted as representing growth in magma chamber cupolas, as wall mushes, or in narrow conduits. Persistent compositions of PO-type crystals and abundant surfaces recording dissolution features correspond to formation within a magma chamber. C-type zoning and R-type zoning have revealed an irregular incorporation of melt and fluid inclusions. These two types of zoning in feldspar are interpreted as preferentially

  12. Quantificação em escala de bancada do volume de ar em ligações prediais de água Measuring air volume in household pipes by means of a pilot scale study

    Directory of Open Access Journals (Sweden)

    Ney Procópio Lopes

    2011-12-01

    Full Text Available A presente pesquisa em escala piloto, simulando trecho de uma rede interligada a um ramal predial, visou quantificar o volume de ar aferido pelos hidrômetros residenciais. Para tal fim, testaram-se ventosas, bloqueadores de ar e válvulas eliminadoras de ar. Sob condições normais de operação da rede, o volume de ar medido pelos hidrômetros é comparável ao encontrado na água natural, não justificando a instalação de equipamento de eliminação de ar de qualquer natureza. Todavia, logo após esvaziamento da rede interligada ao ramal, a sobremedição pode atingir até 21% em condições de pressão máxima na rede de distribuição (500 kPa. Por fim, verificou-se que a menor vazão afluente associa-se ao maior volume de ar aferido pelo hidrômetro. Dessa forma, é possível supor que os consumidores situados na menor faixa de consumo sejam os mais prejudicados pela situação de desabastecimento.The purpose of the present work is to evaluate the volume of air measured in domestic water supply pipe connections. Tests were performed to evaluate the efficiency and applicability of air reducing valves in domestic water supply connections. The results obtained under regular water supply conditions showed that the volume of air in the water measured by the hydrometers is comparable to the one found in natural waters. On the other hand, other tests, right after emptying the network connected to the domestic water supply pipe, revealed that the volume of water which gets to the gauged reservoir comprehends up to 21% of the total air-water volume recorded by the hydrometer for the experiments performed under pressure of 500 kPa.

  13. Photodissociation dynamics of Ar2(+) and Ar3(+) excited by 527 nm photons.

    Science.gov (United States)

    Lepère, V; Picard, Y J; Barat, M; Fayeton, J A; Lucas, B; Béroff, K

    2009-05-21

    The photofragmentation dynamics of Ar(2)(+) and Ar(3)(+) clusters has been investigated at a 527 nm wavelength (2.35 eV) using a setup that allows simultaneous detection of the ionic and neutral fragments in a coincidence experiment. Measurement of positions and times of flight enables in principle a complete description of the fragmentation dynamics. The photofragmentation dynamics of Ar(3)(+) clusters is similar to that of Ar(2)(+) with, in addition, the ejection of a third fragment that can be neutral or ionized via a resonant electron capture. This is attributed to the triangular geometry of the Ar(3)(+) ion.

  14. The effects of acid treatment and sample preparation on 40Ar/39Ar ages

    Science.gov (United States)

    Morgan, L. E.; Davidheiser, B.; Kuiper, K.; Wijbrans, J. R.

    2011-12-01

    Practitioners of K-Ar and 40Ar/39Ar geochronology regularly use dilute acids (typically 5-10% hydrofluoric acid (HF)) to clean mineral grains prior to irradiation (in the case of 40Ar/39Ar), and analysis (e.g. Evernden and Curtis, 1965; Dalrymple, 1967). This treatment has been shown to reduce contamination from atmospheric Ar, which consists largely of 40Ar and thus must be differentiated from radiogenic 40Ar* (Evernden and Curtis, 1965). Acid treatments can also remove fine grained material attached to mineral grains, such as glass shards or devitrified glass, which can affect analyses and is difficult to remove by other means (Evernden and Curtis, 1965). Such treatments were originally examined for their efficacy in reducing atmospheric argon contamination (Dalrymple, 1967) but were not assessed for the possibility of leaching Ar* or K differentially, which would affect both K-Ar and 40Ar/39Ar ages. Indeed, Evernden and Curtis (1965) state that they are simply removing the "outer portions of the crystals" and apparently do not account for the potential for leaching of 40Ar* or K from the mass of their host mineral. Moreover, the capabilities of the K-Ar system in the 1960s was limited to a precision of ca. 3-4% on samples of 1-3 Ma (Cox and Dalrymple, 1967). Effects of smaller magnitude could not have been detected at the time. As the developments of the 40Ar/39Ar system and modern mass spectrometer technology have allowed for precision to approach 0.1%, the potential effects of acid treatment during sample preparation warrant revisiting. Additionally, the use of Calgon for sample disintegration has not previously been quantitatively assessed but is used extensively in some laboratories. Here we present a series of experiments from co-irradiated Fish Canyon sanidine (FCs) and Mes-4 (Kuiper et al., 2008). FCs is used as the mineral standard following standard procedures. Mes-4 splits were treated with H2O (10 minutes, ultrasonic), Calgon (10%, overnight at 50

  15. Demandas de cuidado domiciliar da criança nascida exposta ao HIV na ótica da teoria ambientalista

    Directory of Open Access Journals (Sweden)

    Ivana Cristina Vieira de Lima

    Full Text Available Objetivou-se identificar as demandas de cuidado domiciliar da criança nascida exposta ao HIV, sob a perspectiva da teoria ambientalista. Trata-se de estudo qualitativo exploratório-descritivo realizado de janeiro a abril de 2011. Participaram dez mães infectadas pelo HIV, com crianças nascidas expostas ao vírus, em Fortaleza, Ceará. Constituíram-se como instrumentos de coleta de dados: câmera fotográfica descartável e digital e formulários para captação de informações em saúde associadas ao ambiente domiciliar. Os resultados foram contextualizados de acordo com a teoria e organizados em categorias: "vulnerabilidades associadas à estrutura física da moradia"; "ar intradomiciliar e peridomiciliar impuro"; "água utilizada para consumo"; "rede de esgoto e saneamento"; "iluminação e ventilação da residência". Conclui-se que o ambiente domiciliar oferece condições ambientais desfavoráveis para a criança. Urge a realização de intervenções focalizadas no ambiente domiciliar, para promover a saúde da criança nascida exposta ao HIV.

  16. 40Ar/36Ar in MORB glasses: Constraints on atmosphere and mantle evolution

    International Nuclear Information System (INIS)

    Sarda, P.; Staudacher, T.; Allegre, C.J.; Paris-7 Univ., 75

    1985-01-01

    Argon isotopic composition measurements of MORB glassy samples from the Pacific, Atlantic and Indian Oceans are performed. There is a very large scatter in the 40 Ar/ 36 Ar ratio, from 980 up to 24,400 for bulk rock analyses, which is mainly due to atmospheric contamination: Using the stepwise heating technique, very high ratios are obtained, from 15,000 up to 25,250 which is the highest 40 Ar/ 36 Ar ratio ever measured in MORB. We establish a negative correlation between the highest 40 Ar/ 36 Ar results from stepwise heating and 87 Sr/ 86 Sr ratios, which is perfectly consistent with a two-layered mantle structure. From both 40 Ar and 129 Xe MORB systematics a model is proposed for the kinetics of degassing: a very early and extensive burst, with a time constant of approx.= 4 My, is followed by a slower process of present day type, with a time constant of approx.= 0.5 Gy. The mean age of the atmosphere is so determined to be around 4.4 Gy. (orig./WB)

  17. REFLEXOS DA RECEPÇÃO NO TEXTO LITERÁRIO LATINO – A PARTIR DA ARS POETICA DE HORÁCIO –

    Directory of Open Access Journals (Sweden)

    Francisco Edi de Oliveira Sousa

    2016-01-01

    Full Text Available Este trabalho revisita a literatura latina, lançandolhe um olhar pautado em recente tendência dos estudos literários: a interação texto-receptor. As teorias e métodos que desenvolvem tal tendência convergem ao horizonte de uma poética da leitura. Nesta linha, destacam-se a estética da recepção e a teoria do efeito estético: a primeira corrente analisa a recepção histórica de obras literárias e efeitos estéticos que elas produzem nos receptores; a segunda parte destes princípios, todavia volta-se mais para o texto, permitindo examinar nas obras procedimentos artísticos orientados para a interação com o receptor. Ancorados nestas abordagens, comentamos a recepção de obras literárias no universo romano do início do Império e procedimentos artísticos condicionados por esta interação. Ao fim, as reflexões tecidas encontram respaldo na Ars poetica de Horácio. Palavras-chave: Literatura latina; Ars poetica de Horácio; poética da leitura.

  18. Análise de um protótipo de condicionador de ar adsortivo evaporativo para clima quente e úmido

    Directory of Open Access Journals (Sweden)

    Jesus Marlinaldo de Medeiros

    2015-06-01

    Full Text Available O sistema de condicionamento de ar adsortivo evaporativo funciona com a desumidificação do ar externo, forçando-o a passar através de um adsorvente, onde parte do vapor de água é retido e o ar quase seco é umidificado através de resfriadores evaporativos para redução de sua temperatura. O desumidificador adsortivo utilizou cerca de 4,4 kg de sílica-gel com diâmetro de 2 a 5 mm sobre telas metálicas garantindo maior rigidez à estrutura, melhor distribuição da sílica e circulação do ar. A sílica-gel foi regenerada através de aquecedor elétrico com fluxo de ar forçado por um período de 4 horas. O climatizador comercial tipo resfriador evaporativo foi testado com fibras evaporativas sintéticas e naturais. Os resultados mostraram que dependendo do painel evaporativo ocorre uma maior perda de carga no escoamento, provocando a diminuição da velocidade e comprometendo o rendimento do equipamento. O sistema completo foi testado, verificandose que o desumidificador reduziu a razão de umidade do fluxo de ar, mas o aumento da temperatura do ar associado ao calor de adsorção comprometeu o rendimento do protótipo. Portanto, para obter conforto térmico com o condicionador adsortivo evaporativo será necessário resfriar o ar após o desumidificador com a circulação da água do climatizador.

  19. Legacy K/Ar and 40Ar/39Ar geochronologic data from the Alaska-Aleutian Range batholith of south-central Alaska

    Science.gov (United States)

    Koeneman, Lisa L.; Wilson, Frederic H.

    2018-04-06

    Sample descriptions and analytical data for more than 200 K/Ar and 40Ar/39Ar analyses from rocks of the Alaska-Aleutian Range batholith of south-central Alaska are reported here. Samples were collected over a period of 20 years by Bruce R. Reed and Marvin A. Lanphere (both U.S. Geological Survey) as part of their studies of the batholith.

  20. On the doubly ionized states of Ar2 and their intra- and interatomic decay to Ar23+

    International Nuclear Information System (INIS)

    Stoychev, Spas D.; Kuleff, Alexander I.; Tarantelli, Francesco; Cederbaum, Lorenz S.

    2008-01-01

    Potential energy curves of the Auger state Ar + (2p -1 )-Ar, the different one- and two-site dicationic states Ar 2 ++ (with energies in the range of 32-77 eV), and the lowest two-site tricationic states Ar ++ -Ar + (with energies in the range of 64-76 eV) computed using elaborated ab initio methods are reported. The accessible relaxation channels of the electronic states of Ar ++ -Ar populated by Auger decay are studied. In particular, we study in detail the interatomic Coulombic decay following the population of one-site satellite states of Ar ++ (3s -1 3p -1 )-Ar recently observed experimentally. Other relaxation pathways of Ar ++ -Ar, including radiative charge transfer, nuclear dynamics through curve crossing, and intra-atomic decay processes are also investigated

  1. 40Ar-39Ar age determinations on the Owyhee basalt of the Columbia plateau

    International Nuclear Information System (INIS)

    Bottomley, R.J.; York, D.

    1976-01-01

    40 Ar/ 39 Ar step-heating analyses have been performed on 11 samples of basalt from sites near Owyhee Reservoir of southeastern Oregon, U.S.A. These rocks were extruded during the great flood basalt episode of the Pacific Northwest. The whole-rock points are highly correlated on a plot of 40 Ar/ 36 Ar versus 39 Ar/ 36 Ar, corresponding to a common age of the samples of 14.3+-0.3 m.y. Inspite of this, individual 'plateau' plots of the age versus fraction of 39 Ar released do not give good plateaux. These age spectra exhibit to varying degrees a common structure in which lower age values are found at higher temperatures. This pattern may result from a closed-system redistribution of the argon isotopes. The usefulness of grinding the basalts in removing a loosely held atmospheric argon component is confirmed. (Auth.)

  2. 40Ar/39Ar age and thermal history of the Kirin chondrite

    International Nuclear Information System (INIS)

    Wang, S.; McDougall, I.; Tetley, N.; Harrison, T.M.

    1980-01-01

    The Kirin meteorite, a large (> 2800 kg) H5 chondrite, fell in Kirin Province, China in 1976. A sample from each of the two largest fragments (K-1. K-2) yield 40 Ar/ 39 Ar total fusion ages of 3.63 +- 0.02 b.y. and 2.78 +- 0.02 b.y. respectively. 40 Ar/ 40 Ar age spectra show typical diffusional argon loss profiles. Maximum apparent ages of 4.36 b.y. (K-1) and approx. 4.0 b.y. (K-2) are interpreted as possible minimum estimates for the age of crystallization of the parent body. (orig./ME)

  3. The effects of retrograde reactions and of diffusion on 39Ar-40Ar ages of micas

    DEFF Research Database (Denmark)

    Allaz, Julien; Engi, Martin; Berger, Alfons

    2011-01-01

    Effects of metamorphic reactions occurring during decompression were explored to understand their influence on 39Ar-40Ar ages of micas. Monometamorphic metasediments from the Lepontine Alps (Switzerland) were studied. Collected samples reached lower amphibolite facies during the Barrovian....... XRD-data indicated that some mineral separates prepared for Ar-Ar stepwise heating analysis were monomineralic, whereas others were composed of two white micas (muscovite with paragonite or margarite), or biotite and chlorite. In monomineralic samples 37Ar/39Ar and 38Ar/39Ar (proportional to Ca....../K and Cl/K ratios) did not change and the resulting ages can be interpreted unambiguously. In mineral separates containing two white micas, Ca/K and Cl/K ratios were variable, reflecting non-simultaneous laboratory degassing of the two heterochemical Ar-reservoirs. These ratios were used to identify each...

  4. Efeito de níveis de água, coberturas do solo e condições ambientais na temperatura do solo e no cultivo de morangueiro em ambiente protegido e a céu aberto Effect of water levels, soil covers and enviroment in maximum soil temperature in strawberry crop in field and greenhouse

    OpenAIRE

    Regina C. de M. Pires; Marcos V. Folegatti; Mário J. Pedro Júnior; Emílio Sakai; Francisco A. Passos; Flávio B. Arruda; Rinaldo de O. Calheiros

    2004-01-01

    A temperatura do solo é um importante parâmetro no cultivo do morangueiro, pois interfere no desenvolvimento vegetativo, na sanidade e na produção. O objetivo do presente trabalho foi avaliar o efeito de diferentes níveis de água, coberturas de canteiro em campo aberto e em ambiente protegido, na temperatura máxima do solo no cultivo do morangueiro. Foram realizados dois experimentos: um em cultivo protegido e outro a campo aberto, em Atibaia - SP, em esquema fatorial 2 x 3 (coberturas do sol...

  5. Geochronology and thermochronology by the sup 40 Ar/ sup 39 Ar method

    Energy Technology Data Exchange (ETDEWEB)

    McDougall, I. (Australian National Univ., Canberra (Australia)); Harrison, T.M. (State Univ. of New York, Albany, NY (USA))

    1988-01-01

    This work is a response to the authors' belief that there is a need for a monograph on {sup 40}Ar/{sup 39}Ar dating to provide concise knowledge concerning the application of this method to geological studies. They aim to provide a reasonably comprehensive but by no means exhaustive coverage of the principles and practices of {sup 40}Ar/{sup 39}Ar dating, with emphasis on interpretation of results. In attempting to provide an overview of the current state of knowledge, they commonly cite examples from the available literature. They draw rather heavily upon their own work, because they feel comfortable with their own examples. (author).

  6. 40Ar/39Ar and K-Ar age constraints on the timing of regional deformation, south coast of New South Wales, Lachlan Fold Belt: problems and implications

    International Nuclear Information System (INIS)

    Fergusson, C.L.; Phillips, D.

    2001-01-01

    Four slate samples from subduction complex rocks exposed on the south coast of New South Wales, south of Batemans Bay, were analysed by K-Ar and 40 Ar/ 39 Ar step-heating methods, One sample contains relatively abundant detrital muscovite flakes that are locally oblique to the regional cleavage in the rock, whereas the remaining samples appear to contain sparse detrital muscovite. Separates of detrital muscovite yielded plateau ages of 505 + 3 Ma and 513 + 3 Ma indicating that inheritance has not been eliminated by metamorphism and recrystallisation. Step-heating analyses of whole-rock chips from all four slate samples produced discordant apparent age spectra with 'saddle shapes' following young apparent ages at the lowest temperature increments. Elevated apparent ages associated with the highest temperature steps are attributed to the presence of variable quantities of detrital muscovite ( 40 Ar/ 39 Ar integrated ages of ca 455Ma, which are some 15-30 million years older than K-Ar ages for the same samples. These discrepancies suggest that the slates have also been affected by recoil loss/redistribution of 39 Ar, Ieading to anomalously old 40 Ar/ 39 Ar ages. Two other samples, from slaty tectonic melange and intensely cleaved slate, yielded average 40 Ar/ 39 Ar integrated ages of ca 424Ma, which are closer to associated mean K-Ar ages of 423 + 4Ma and 409 + 16Ma, respectively. Taking into account the potential influences of recoil loss/redistribution of 39 Ar and inheritance, the results from the latter samples suggest a maximum age of ca 440 Ma for deformation/metamorphism. The current results indicate that recoil and inheritance problems may also have affected whole-rock 40 Ar/ 39 Ar data reported from other regions of the Lachlan Fold Belt. Therefore, until these effects are adequately quantified, models for the evolution of the Lachlan Fold Belt, that are based on such whole-rock 40 Ar/ 39 Ar data, should be treated with caution. Copyright (2001) Geological

  7. Alignment and orientation of Ar+ in He+-Ar collisions

    International Nuclear Information System (INIS)

    Moudry, B.W.; Yenen, O.; Jaecks, D.H.

    1994-01-01

    We have measured the alignment and orientation parameters of the 2 F 7/2 0 and 2 F 5/2 0 states of Ar + formed in the two-electron process; He + +Ar→He(1s 2 )+Ar + (3p 4 4p'). These have been measured at a collision energy of 0.25 keV/amu and for scattering angles ranging from 0.94 to 3.75 . First, by comparing the orientation prameter for the Ar + [(3p 4 [ 1 D]4p' 2 F 7/2 0 ] and the Ar + [(3p 4 [ 1 D]4p' 2 F 5/2 0 ] states, we have experimentally determined the importance of the spin-dependent interactions for the present collision system, by testing the Percival-Seaton hypothesis of spin independence. If the Percival-Seaton hypothesis holds for this system, the orientation parameter should be J-independent. Secondly, the magnitude of the orientation prameter can be interpreted as resulting from the collective circulation of the unexcited 3p 4 electrons and the excited 4p electron. The direction of this collective circulation is compared to the propensity rule for colliding di-atom systems. (orig.)

  8. 3 to 15 keV Ar+ induced Auger electron emission from Si and Ar

    International Nuclear Information System (INIS)

    Kempf, J.; Kaus, G.

    1977-01-01

    Ar + induced Auger electrons from Si and Ar were investigated at bombardment energies between 3-15 keV and target currents of a few μA. The Auger electron yields were compared with secondary ion yields of Si and Ar by simultaneous SIMS-AES measurements. In the ion induced Auger spectra of Si five Auger peaks and in the Ar spectra three Auger peaks were observed. The ion induced Auger electron yield of Si and Ar were found to be strongly dependent upon the primary ion energy. 'Bulk like' and 'atomic like' Auger transitions of ion induced Auger electrons of Si were observed. (orig.) [de

  9. Androgen Receptor-Mediated Growth Suppression of HPr-1AR and PC3-Lenti-AR Prostate Epithelial Cells.

    Directory of Open Access Journals (Sweden)

    Young-Chae Kim

    Full Text Available The androgen receptor (AR mediates the developmental, physiologic, and pathologic effects of androgens including 5α-dihydrotestosterone (DHT. However, the mechanisms whereby AR regulates growth suppression and differentiation of luminal epithelial cells in the prostate gland and proliferation of malignant versions of these cells are not well understood, though they are central to prostate development, homeostasis, and neoplasia. Here, we identify androgen-responsive genes that restrain cell cycle progression and proliferation of human prostate epithelial cell lines (HPr-1AR and PC3-Lenti-AR, and we investigate the mechanisms through which AR regulates their expression. DHT inhibited proliferation of HPr-1AR and PC3-Lenti-AR, and cell cycle analysis revealed a prolonged G1 interval. In the cell cycle, the G1/S-phase transition is initiated by the activity of cyclin D and cyclin-dependent kinase (CDK complexes, which relieve growth suppression. In HPr-1AR, cyclin D1/2 and CDK4/6 mRNAs were androgen-repressed, whereas CDK inhibitor, CDKN1A, mRNA was androgen-induced. The regulation of these transcripts was AR-dependent, and involved multiple mechanisms. Similar AR-mediated down-regulation of CDK4/6 mRNAs and up-regulation of CDKN1A mRNA occurred in PC3-Lenti-AR. Further, CDK4/6 overexpression suppressed DHT-inhibited cell cycle progression and proliferation of HPr-1AR and PC3-Lenti-AR, whereas CDKN1A overexpression induced cell cycle arrest. We therefore propose that AR-mediated growth suppression of HPr-1AR involves cyclin D1 mRNA decay, transcriptional repression of cyclin D2 and CDK4/6, and transcriptional activation of CDKN1A, which serve to decrease CDK4/6 activity. AR-mediated inhibition of PC3-Lenti-AR proliferation occurs through a similar mechanism, albeit without down-regulation of cyclin D. Our findings provide insight into AR-mediated regulation of prostate epithelial cell proliferation.

  10. Ensaio clínico, aberto, controlado sobre a adição de brometo de ipratrópio ao fenoterol no tratamento da crise de asma em adultos Open, controlled clinical assay of the addition of ipratropium bromide to fenoterol in the treatment of acute asthma crisis in adults

    Directory of Open Access Journals (Sweden)

    Solange Diccini

    1999-12-01

    Full Text Available No tratamento da crise de asma, empregam-se doses repetidas de drogas b2-agonistas por via inalatória. O efeito da adição do brometo de ipratrópio (BI ao b2-agonistas é controverso em adultos. OBJETIVO: Avaliar se adição de BI ao fenoterol, em tratamentos inalatórios repetidos, induz a maior broncodilatação, com reversibilidade da crise e alta da emergência em pacientes em crise grave de asma. LOCAL DO ESTUDO: Serviço de Pronto-Atendimento de Pneumologia, Disciplina de Pneumologia da Unifesp-Hospital São Paulo, no período de julho de 1995 a fevereiro de 1997. TIPO DE ESTUDO: Aberto, randomizado, paralelo. Alta da emergência determinada pelo VEF1 e PFE > 60% do previsto. CASUÍSTICA E MÉTODOS: Cento e vinte pacientes em crise de asma foram divididos em dois grupos (N = 60: fenoterol (F e brometo de ipratrópio + fenoterol (BIF com VEF1 e PFE Repeated dosis of inhaled b2-agonists have been used in the treatment of acute asthma. The effect of added ipratropium bromide (IB to b2-agonist is controversial in adults. OBJECTIVE: To evaluate if addition of IB to fenoterol, in repeated doses, induces a greater bronchodilation, a greater reversion of the attack, and discharge from emergency unit in adults with acute severe asthma. SETTING: Pneumology Emergency Department, Unifesp-Hospital São Paulo, in the period from July 1995 to February 1997. TYPE OF STUDY: Open, randomized and parallel study. Discharge from the hospital: FEV1 and PEF > 60% of the predicted value. METHODS: 120 patients with FEV1 and PEF < 50% of the predicted value were divided into two groups (N = 60: fenoterol (F and ipratropium bromide + fenoterol (IBF. Each group received inhalation treatment through a metered-dose inhaler (MDI attached to a holding chamber, administered at 30-minute interval, for a total of three treatments. In the group F four puffs of fenoterol (400 mg were administered, and in the IBF group, 160 mg of BI and 400 mg of fenoterol (four puffs

  11. Analysis list: Ar [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Ar Gonad,Kidney,Prostate + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/targe...t/Ar.1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Ar.5.tsv http://dbarchive.biosciencedbc.jp/...kyushu-u/mm9/target/Ar.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Ar.Gonad.tsv,http://dbarchive.bioscience...dbc.jp/kyushu-u/mm9/colo/Ar.Kidney.tsv,http://dbarchive.bioscienced...bc.jp/kyushu-u/mm9/colo/Ar.Prostate.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Gonad.gml,http://dbarchive.bioscience

  12. Ramon Llull's Ars Magna

    DEFF Research Database (Denmark)

    Jensen, Thessa

    2017-01-01

    might be a viable and valuable approach to understand some of the challenges and possibilities found in computer science and ethics. Vita Llull was born in 1232 in Palma de Mallorca, a melting pot for different cul-tures and religions at the time. Being educated at the king’s court, Llull learned...... of belief, life, and God as such. Computer Science? Llull was an inspiration for later scientists, most notably Giordano Bruno, Athanasius Kirchner, Agrippa of Nettesheim and Gottfried Wilhelm Leibniz, whose dissertation De Arte Combinatoria begins with a discussion of Llull’s Ars Magna. Umberto Eco also......-ple of Mallorca have since tried to have Llull canonised as a saint. Ars Magna A few years before his death Llull began to write the most thorough and final version of his Ars Magna, the Ars Generalis Ultima [3]. The books explain the different figures of the Ars, its principles, questions, descriptions...

  13. Uma análise de aspectos relacionados ao desenvolvimento e adoção de Enterprise Resources Planning livre de código aberto An analysis of aspects related to the development and adoption of free open source Enterprise Resources Planning

    Directory of Open Access Journals (Sweden)

    Rogério Atem de Carvalho

    2009-12-01

    Full Text Available Sistemas Integrados de Gestão ou Enterprise Resources Planning - ERP possibilitam o processamento das informações necessárias em uma empresa usando um único banco de dados. Muito tem se escrito sobre este tipo de software, abordando questões como o alto custo da aquisição de licenças, e a dependência de consultoria para a sua adaptação e implantação nas empresas. Atualmente vem crescendo o desenvolvimento e uso de ERP Livre de Código Aberto (FOS-ERP. Porém verifica-se que este tipo de sistema ainda não é suficientemente explorado, mesmo no meio acadêmico. Este artigo relata alguns trabalhos publicados sobre o assunto e levanta questões que devem ser tratadas por pesquisadores e demais interessados para adequar e viabilizar o uso desses sistemas conforme a realidade nacional. Assim, após uma introdução ao tema, são apresentadas algumas diferenças entre o FOS-ERP e seus equivalentes proprietários (Proprietary ERP ou P-ERP em termos de modelos de negócios, seleção, customização e evolução. Em seguida são elencados alguns desafios e oportunidades que o FOS-ERP pode oferecer a usuários, fornecedores, pesquisadores e colaboradores individuais. Concluindo, este artigo busca ampliar a discussão sobre FOS-ERP, destacando fatores tais como seu potencial de inovação tecnológica e estratégias de negócios.Enterprise Resources Planning (ERP enables the processing of information required in an enterprise, using a single database. Much has been written about this type of software, addressing issues such as the high cost of licenses acquisitions, and the dependence on consultants for its adaptation and implementation in companies. Currently the development and use of ERP Free Open Source (FOS-ERP has increased. However, this type of system is still not sufficiently explored, even in academia. This article analyses some papers on the subject, and raises questions that must be addressed by researchers and other stakeholders

  14. The celecoxib derivatives AR-12 and AR-14 induce autophagy and clear prion-infected cells from prions.

    Science.gov (United States)

    Abdulrahman, Basant A; Abdelaziz, Dalia; Thapa, Simrika; Lu, Li; Jain, Shubha; Gilch, Sabine; Proniuk, Stefan; Zukiwski, Alexander; Schatzl, Hermann M

    2017-12-14

    Prion diseases are fatal infectious neurodegenerative disorders that affect both humans and animals. The autocatalytic conversion of the cellular prion protein (PrP C ) into the pathologic isoform PrP Sc is a key feature in prion pathogenesis. AR-12 is an IND-approved derivative of celecoxib that demonstrated preclinical activity against several microbial diseases. Recently, AR-12 has been shown to facilitate clearance of misfolded proteins. The latter proposes AR-12 to be a potential therapeutic agent for neurodegenerative disorders. In this study, we investigated the role of AR-12 and its derivatives in controlling prion infection. We tested AR-12 in prion infected neuronal and non-neuronal cell lines. Immunoblotting and confocal microscopy results showed that AR-12 and its analogue AR-14 reduced PrP Sc levels after only 72 hours of treatment. Furthermore, infected cells were cured of PrP Sc after exposure of AR-12 or AR-14 for only two weeks. We partially attribute the influence of the AR compounds on prion propagation to autophagy stimulation, in line with our previous findings that drug-induced stimulation of autophagy has anti-prion effects in vitro and in vivo. Taken together, this study demonstrates that AR-12 and the AR-14 analogue are potential new therapeutic agents for prion diseases and possibly protein misfolding disorders involving prion-like mechanisms.

  15. Práticas de responsabilidade socioambiental nas empresas de capital aberto de Santa Catarina listadas na BM&FBOVESPA = Social responsibility practices in open capital companies from Santa Catarina listed on BM&FBOVESPA

    Directory of Open Access Journals (Sweden)

    Daniela Di Domenico

    2015-08-01

    Full Text Available Este artigo tem como objetivo identificar as práticas de ações de responsabilidade social corporativa das sociedades anônimas de capital aberto de Santa Catarina listadas na BM&FBovespa. A justificativa da pesquisa está atrelada à influência da evidenciação dessas informações para os investidores, pesquisadores e usuários das informações ambientais. Quanto aos procedimentos metodológicos o estudo caracteriza-se como exploratório quanto aos objetivos, documental em relação aos procedimentos e a abordagem do problema é predominantemente qualitativa. As empresas que fazem parte da amostra são: BRF S.A., BUETTNER S.A., CASAN, KARSTEN S.A e WEG S.A. Foram várias as práticas de responsabilidade social e ambiental evidenciadas, mas se pode identificar que todas têm como objetivo divulgar a empresa, além do objetivo principal da ação realizada. É possível destacar as principais práticas como sendo as ações e cuidados para o consumo consciente da água e energia, usando fontes que não sejam prejudiciais ao meio ambiente. Outra ação em destaque é o cuidado com a destinação dos resíduos sólidos e líquidos, gerados nos processos operacionais das empresas. A preocupação com a poluição da atmosfera também é evidente, por ser um dos principais problemas ambientais na atualidade.This article aims at identifying the practices of corporate social responsibility of corporations with open capital of Santa Catarina listed BM&FBovespa. The justification of this research is related to the influence of the disclosure of information for the investors, researchers and users of environmental information. In the methodological procedures, the study is characterized as exploratory as its goals, documental regarding the procedures and its approach to the problem is predominantly qualitative. The companies included in the sample are: BRF SA, BUETTNER SA, CASAN, KARSTEN SA and WEG SA. There were several social and environmental

  16. POTENCIAL DOS RECURSOS EDUCACIONAIS ABERTOS PARA INTEGRAÇÃO DAS TECNOLOGIAS E CONVERGÊNCIA ENTRE AS MODALIDADES NA UFSM. POTENTIAL OF OPEN EDUCATIONAL RESOURCES FOR TECHNOLOGY INTEGRATION AND CONVERGENCE BETWEEN THE MODALITIES AT UFSM

    Directory of Open Access Journals (Sweden)

    Elena Maria Mallmann

    2013-11-01

    Full Text Available O foco de análise é a implementação e o fomento de práticas escolares, para potencializar a integração das tecnologias e a convergência entre as modalidades na Universidade Federal de Santa Maria (UFSM, Brasil, por meio de Recursos Educacionais Abertos. Objetivamos sistematizar princípios conceituais e práticas que balizam a utilização de recursos educacionais abertos, com vistas a maximizar diálogo e produção curricular mediados por tecnologias. Os procedimentos metodológicos de pesquisa-ação (planejamento participativo, observação e questionários survey geraram dados para análise referente à programação e à problematização de Recursos Educacionais Abertos, em cursos de graduação e pós-graduação mediados pelo Moodle institucional. Os resultados de acoplamento da pesquisa à ação didático-metodológica inovadora na UFSM evidenciam crescimento exponencial na programação semanal de recursos e atividades de estudo no Moodle. A afirmação conclusiva destaca que a disponibilização e o suporte técnico institucional de tecnologias em rede ampliam condições para integração e convergência entre as modalidades, especialmente no âmbito dos recursos educacionais abertos como hipertextos programados em html. The analysis focus is the implementation and the fomentation of school practices in order to enhance the technology integration and the convergence between the modalities at the Federal University of Santa Maria (UFSM, Brazil, through open educational resources. We aimed to systematize conceptual principles and practices that beacon the use of open educational resources, aspiring to maximize dialogue and curricular production mediated by technologies. The action research methodological procedures (participatory planning, observation and survey questionnaires generated analysis data relative to the programming and problematization of open educational resources, in undergraduate and graduate courses mediated

  17. High-resolution Auger spectroscopy on 79 MeV Ar5+, 89 MeV Ar6+, and 136 MeV Ar7+ ions after excitation by helium

    International Nuclear Information System (INIS)

    Schneider, T.

    1988-01-01

    In this thesis the atomic structure of highly excited Ar 6+ and Ar 7+ ions was studied. For this 79 MeV Ar 5+ , 89 MeV Ar 6+ , and 136 MeV Ar 7+ ions of a heavy ion accelerator were excited by a He gas target to autoionizing states and the Auger electrons emitted in the decay were measured in highly-resolving state. The spectra were taken under an observational angle of zero degree relative to the beam axis in order to minimize the kinematical broadening of the Auger lines. (orig./HSI) [de

  18. Comportamento do Volume de Negociações e do Risco de Mercado antes e após os Resultados das Eleições Presidenciais em 2014: Um Estudo com Empresas Brasileiras de Capital Aberto

    Directory of Open Access Journals (Sweden)

    Josilene da Silva Barbosa

    2017-01-01

    Full Text Available Objetivo: Consiste em analisar o efeito do resultado das eleições presidenciais em 2014 no risco de mercado medido em função do volume de títulos negociados pelas empresas brasileiras listadas na BM&FBOVESPA. Fundamento: Método: Nessa pesquisa a composição de amostras corresponde a todas as empresas com ações negociadas na Bovespa no período que corresponde às eleições para presidente da república realizada em outubro de 2014. Os dados que serviram de base para a realização dos testes são o preço das ações e volume de negociação de todas as empresas brasileiras de capital aberto, com títulos negociados na BM&FBOVESPA no período de 01 de janeiro de 2010 a 31 de agosto de 2015. Para análise dos dados, especificamente foi utilizada a metodologia teste de Chow (1960. Resultados: No estudo após proceder ao teste, constatou-se que a indefinição do cenário político pode ter provocado uma instabilidade no risco das empresas a um nível de significância de 5%. Os resultados mostram que 131 empresas apresentaram quebra estrutural o que corresponde a 71% da amostra, demonstrando que o risco das empresas em relação a investimentos mudou tanto para mais quanto para menos. Contribuições: O estudo é relevante para o mercado, pois, mostra que em períodos de instabilidade política o comportamento do mercado pode-se alterar, elevando o risco em função do volume de negociações. Ao prever esse tipo de alteração no mercado os investidores poderão se prevenir antecipadamente, tomando decisões que consideram esse tipo de evento, bem como as empresas também poderão tomar decisões preventivas.

  19. A compilation of 40Ar-39 and K-Ar ages: report 25

    International Nuclear Information System (INIS)

    Hunt, P.A.; Roddick, J.C.

    1996-01-01

    Twenty-three 40 Ar- 39 Ar age determinations (including two potassium-argon analyses) carried out by the Geological Survey of Canada are reported. Each age determination is accompanied by a description of the rock and mineral concentrate used; brief interpretative comments regarding the geological significance of each age are also provided where possible. The experimental procedures employed are described in outline. An index of all Geological Survey of Canada K-Ar age determinations published in this format has been prepared using NTS quadrangles as the primary reference. (author). 6 refs., 2 tabs., 1 fig

  20. Arsénico en el agua de bebida: un problema de salud pública Arsênio na água de beber: um problema de saúde pública

    Directory of Open Access Journals (Sweden)

    Alexandra Galetovic Carabantes

    2003-12-01

    Full Text Available La presencia de arsénico en el ambiente es un problema de salud pública debido a que se trata de un evento de alta frecuencia que ha sido detectado en países como Argentina, Brasil, Chile, China, India, México y Taiwán, entre otros. El arsénico fue clasificado por la International Agency for Research on Cancer (IARC, como un agente carcinogénico para humanos con base en estudios epidemiológicos que relacionan la ingestión de arsénico en el agua de bebida y cáncer en la piel y estudios ocupacionales que relacionan la exposición al arsénico y cáncer de pulmón. La Organización Mundial de la Salud (OMS recomienda um valor orientador para agua de bebida de 10 mg As/L. Por su parte la Environmental Protection Agency (EPA, considerando estimativas de riesgo realizadas utilizando modelos estadísticos basados en observaciones en humanos y extrapolando los datos para concentraciones inferiores a 50 µg/L, reducirá el valor guía para arsénico en el agua de bebida de 50 µg/L para 10 µg/L. La utilización de biomarcadores permite el desarrollo de la epidemiología molecular que promete ser una herramienta que ayudará a detectar efectos tempranos en poblaciones expuestas, permitiendo la prevención de efectos nocivos considerando las características genéticas de las poblaciones.A presença de arsênio no ambiente é um problema de saúde pública por ser um evento de alta freqüência detectado em países como Argentina, Brasil, Chile, China, Índia, México e Taiwan, entre outros. O arsênio foi classificado pela Agência Internacional de Pesquisa sobre Câncer (IARC, como um agente carcinogênico para humanos com base em estudos epidemiológicos que relacionam a ingestão de arsênico na água para consumo humano e câncer na pele e estudos ocupacionais que relacionam a exposição ao arsênico e câncer no pulmão.A Organização Mundial da Saúde (OMS recomenda um valor orientador para água de beber de 10 mg As/L, enquanto que a

  1. Cross Sections of the 36Ar(d,α)34mCl, 40Ar(d,α)38Cl and 40Ar(d,p)41Ar Nuclear Reactions below 8.4 MeV

    Science.gov (United States)

    Engle, J W; Severin, G W; Barnhart, T E; Knutson, L D; Nickles, R J

    2011-01-01

    We have measured the cross section for production of the medically interesting isotope 34mCl, along with 38Cl and 41Ar, using deuteron bombardments of 36Ar and 40Ar below 8.4 MeV. ALICE/ASH analytical codes were employed to determine the shape of nuclear excitation functions, and experiments were performed using the University of Wisconsin tandem electrostatic accelerator to irradiate thin targets of argon gas. PMID:22041299

  2. Histone demethylase JMJD1A promotes alternative splicing of AR variant 7 (AR-V7) in prostate cancer cells.

    Science.gov (United States)

    Fan, Lingling; Zhang, Fengbo; Xu, Songhui; Cui, Xiaolu; Hussain, Arif; Fazli, Ladan; Gleave, Martin; Dong, Xuesen; Qi, Jianfei

    2018-05-15

    Formation of the androgen receptor splicing variant 7 (AR-V7) is one of the major mechanisms by which resistance of prostate cancer to androgen deprivation therapy occurs. The histone demethylase JMJD1A (Jumonji domain containing 1A) functions as a key coactivator for AR by epigenetic regulation of H3K9 methylation marks. Here, we describe a role for JMJD1A in AR-V7 expression. While JMJD1A knockdown had no effect on full-length AR (AR-FL), it reduced AR-V7 levels in prostate cancer cells. Reexpression of AR-V7 in the JMJD1A-knockdown cells elevated expression of select AR targets and partially rescued prostate cancer cell growth in vitro and in vivo. The AR-V7 protein level correlated positively with JMJD1A in a subset of human prostate cancer specimens. Mechanistically, we found that JMJD1A promoted alternative splicing of AR-V7 through heterogeneous nuclear ribonucleoprotein F (HNRNPF), a splicing factor known to regulate exon inclusion. Knockdown of JMJD1A or HNRNPF inhibited splicing of AR-V7, but not AR-FL, in a minigene reporter assay. JMJD1A was found to interact with and promote the recruitment of HNRNPF to a cryptic exon 3b on AR pre-mRNA for the generation of AR-V7. Taken together, the role of JMJD1A in AR-FL coactivation and AR-V7 alternative splicing highlights JMJD1A as a potentially promising target for prostate cancer therapy.

  3. A Refined Astronomically Calibrated 40Ar/39Ar Age for Fish Canyon Sanidine

    DEFF Research Database (Denmark)

    Rivera, Tiffany; Storey, Michael; Zeeden, Christian

    2011-01-01

    Intercalibration between the astronomical and radio-isotopic dating methods provides a means to improving accuracy and reducing uncertainty of an integrated, multi-chronometer geologic timescale. Here we report a high-precision 40Ar/39Ar age for the Fish Canyon sanidine (FCs) neutron fluence...... sanidine age of 0.7674±0.0022 Ma (2σ, external errors) is indistinguishable from the ID-TIMS U/Pb zircon age (0.7671±0.0019 Ma). The consistency between the astronomically calibrated 40Ar/39Ar sanidine age and U/Pb zircon age for this Quaternary unit suggests that agreement between these two radio-isotopic...... dating techniques is now achievable at better than±0.3% (2σ) in the youngest part of geologic time (

  4. Androgen Receptor Variant AR-V9 Is Coexpressed with AR-V7 in Prostate Cancer Metastases and Predicts Abiraterone Resistance.

    Science.gov (United States)

    Kohli, Manish; Ho, Yeung; Hillman, David W; Van Etten, Jamie L; Henzler, Christine; Yang, Rendong; Sperger, Jamie M; Li, Yingming; Tseng, Elizabeth; Hon, Ting; Clark, Tyson; Tan, Winston; Carlson, Rachel E; Wang, Liguo; Sicotte, Hugues; Thai, Ho; Jimenez, Rafael; Huang, Haojie; Vedell, Peter T; Eckloff, Bruce W; Quevedo, Jorge F; Pitot, Henry C; Costello, Brian A; Jen, Jin; Wieben, Eric D; Silverstein, Kevin A T; Lang, Joshua M; Wang, Liewei; Dehm, Scott M

    2017-08-15

    Purpose: Androgen receptor (AR) variant AR-V7 is a ligand-independent transcription factor that promotes prostate cancer resistance to AR-targeted therapies. Accordingly, efforts are under way to develop strategies for monitoring and inhibiting AR-V7 in castration-resistant prostate cancer (CRPC). The purpose of this study was to understand whether other AR variants may be coexpressed with AR-V7 and promote resistance to AR-targeted therapies. Experimental Design: We utilized complementary short- and long-read sequencing of intact AR mRNA isoforms to characterize AR expression in CRPC models. Coexpression of AR-V7 and AR-V9 mRNA in CRPC metastases and circulating tumor cells was assessed by RNA-seq and RT-PCR, respectively. Expression of AR-V9 protein in CRPC models was evaluated with polyclonal antisera. Multivariate analysis was performed to test whether AR variant mRNA expression in metastatic tissues was associated with a 12-week progression-free survival endpoint in a prospective clinical trial of 78 CRPC-stage patients initiating therapy with the androgen synthesis inhibitor, abiraterone acetate. Results: AR-V9 was frequently coexpressed with AR-V7. Both AR variant species were found to share a common 3' terminal cryptic exon, which rendered AR-V9 susceptible to experimental manipulations that were previously thought to target AR-V7 uniquely. AR-V9 promoted ligand-independent growth of prostate cancer cells. High AR-V9 mRNA expression in CRPC metastases was predictive of primary resistance to abiraterone acetate (HR = 4.0; 95% confidence interval, 1.31-12.2; P = 0.02). Conclusions: AR-V9 may be an important component of therapeutic resistance in CRPC. Clin Cancer Res; 23(16); 4704-15. ©2017 AACR . ©2017 American Association for Cancer Research.

  5. Single-crystal 40Ar/39Ar incremental heating reveals bimodal sanidine ages in the Bishop Tuff

    Science.gov (United States)

    Andersen, N. L.; Jicha, B. R.; Singer, B. S.

    2015-12-01

    The 650 km3 Bishop Tuff (BT) is among the most studied volcanic deposits because it is an extensive marker bed deposited just after the Matuyama-Brunhes boundary. Reconstructions of the vast BT magma reservoir from which high-silica rhyolite erupted have long influenced thinking about how large silicic magma systems are assembled, crystallized, and mixed. Yet, the longevity of the high silica rhyolitic melt and exact timing of the eruption remain controversial due to recent conflicting 40Ar/39Ar sanidine vs. SIMS and ID-TIMS U-Pb zircon dates. We have undertaken 21 40Ar/39Ar incremental heating ages on 2 mm BT sanidine crystals from pumice in 3 widely separated outcrops of early-erupted fall and flow units. Plateau ages yield a bimodal distribution: a younger group has a mean of 766 ka and an older group gives a range between 772 and 782 ka. The younger population is concordant with the youngest ID-TIMS and SIMS U-Pb zircon ages recently published, as well as the astronomical age of BT in marine sediment. Of 21 crystals, 17 yield older, non-plateau, steps likely affected by excess Ar that would bias traditional 40Ar/39Ar total crystal fusion ages. The small spread in older sanidine ages, together with 25+ kyr of pre-eruptive zircon growth, suggest that the older sanidines are not partially outgassed xenocrysts. A bimodal 40Ar/39Ar age distribution implies that some fraction of rhyolitic melt cooled below the Ar closure temperature at least 10 ky prior to eruption. We propose that rapid "thawing" of a crystalline mush layer released older crystals into rhyolitic melt from which sanidine also nucleated and grew immediately prior to the eruption. High precision 40Ar/39Ar dating can thus provide essential information on thermo-physical processes at the millenial time scale that are critical to interpreting U-Pb zircon age distributions that are complicated by large uncertainties associated with zircon-melt U-Th systematics.

  6. Optical characteristics of a RF DBD plasma jet in various {Ar}/ {O}_{2}Ar/O2 mixtures

    Science.gov (United States)

    Falahat, A.; Ganjovi, A.; Taraz, M.; Ravari, M. N. Rostami; Shahedi, A.

    2018-02-01

    In this paper, using the optical emission spectroscopy (OES) technique, the optical characteristics of a radiofrequency (RF) plasma jet are examined. The Ar/O2 mixture is taken as the operational gas and, the Ar percentage in the Ar/O2 mixture is varied from 70% to 95%. Using the optical emission spectrum analysis of the RF plasma jet, the excitation temperature is determined based on the Boltzmann plot method. The electron density in the plasma medium of the RF plasma jet is obtained by the Stark broadening of the hydrogen Balmer H_{β }. It is mostly seen that, the radiation intensity of Ar 4p→ 4s transitions at higher argon contributions in Ar/O2 mixture is higher. It is found that, at higher Ar percentages, the emission intensities from atomic oxygen (O) are higher and, the line intensities from the argon atoms and ions including O atoms linearly increase. It is observed that the quenching of Ar^{*} with O2 results in higher O species with respect to O2 molecules. In addition, at higher percentages of Ar in the Ar/O2 mixture, while the excitation temperature is decreased, the electron density is increased.

  7. ASPECTOS EPIDEMIOLÓGICOS DE UM FOCO DE TUNGÍASE (Tunga penetrans, SIPHONAPTERA EM UM SISTEMA INTENSIVO DE SUÍNOS CRIADOS AO AR LIVRE EPIDEMIOLOGICAL ASPECTS OF A FOCUS OF Tunga penetrans INFESTATION IN OUTDOOR PIG PRODUCTION

    Directory of Open Access Journals (Sweden)

    Osmar Antônio Dalla Costa

    2007-09-01

    Full Text Available

    O sistema intensivo de produção de suínos criados ao ar livre (SISCAL é caracterizado por manter os suínos em piquetes com cobertura vegetal, nas fases de reprodução, maternidade e creche, cercados com tela e/ou fios de arame eletrificado. Este trabalho teve por objetivo relatar aspectos epidemiológicos de um foco de tungíase ocorrido em um SISCAL. Foram examinados clinicamente 72 animais, sendo 6 cachaços, 9 fêmeas lactantes, 13 em gestação e 6 em cobrição, 20 leitões lactantes e 34 leitões desmamados e transferidos para unidades de terminação. Verificou-se que nenhum dos cachaços estava infestado (granja 1= 48 e que em 50% do total de fêmeas examinadas ocorreram lesões com maior freqüência nos tetos, o que nas porcas lactantes deu origem à agalaxia por obstrução do canal galactóforo ocasionando involução da glândula mamária. Em 90% dos leitões lactantes constatou-se dificuldade de locomoção causada pela presença do parasito na região plantar do casco e 25% apresentavam, além disto, lesões no jarrete. Dos leitões desmamados transferidos para unidades de terminação em confinamento, com 40-47 dias (granja 2, n=24 e com 70 dias (granja 3, n= 10 de idade 100% e 80%, respectivamente. ainda apresentavam lesões semelhantes às observadas em leitões lactantes. Conclui-se que a tungíase pode afetar suínos criados ao ar livre podendo causar agalaxia em porcas lactantes e dificuldade de locomoção em leitões lactantes e desmamados.

    PALAVRAS-CHAVE: Tunga penetrans; bicho-de-pé; tungíase; sistema intensivo de suínos criados ao ar livre; agalaxia.

    The outdoors intensive-type pig production is characterized by maintaining swine during

  8. Cross sections of the 36Ar(d,α)34mCl, 40Ar(d,α)38Cl, and 40Ar(d,p)41Ar nuclear reactions below 8.4 MeV.

    Science.gov (United States)

    Engle, J W; Severin, G W; Barnhart, T E; Knutson, L D; Nickles, R J

    2012-02-01

    We have measured the cross section for production of the medically interesting isotope (34m)Cl, along with (38)Cl and (41)Ar, using deuteron bombardments of (36)Ar and (40)Ar below 8.4 MeV. ALICE/ASH analytical codes were employed to determine the shape of nuclear excitation functions, and experiments were performed using the University of Wisconsin tandem electrostatic accelerator to irradiate thin targets of argon gas. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. Classical treatment of Li2++Ar and He2++Ar collisions

    International Nuclear Information System (INIS)

    Jorge, A; Illescas, Clara; Pons, B

    2015-01-01

    Classical Trajectory Monte Carlo calculations are carried out for Li 2+ +Ar and He 2+ +Ar collisions, motivated by recent experiments on these systems. Cross sections for electron capture, projectile electron loss and target multiple ionization processes are evaluated and compared to the experimental values in the 75-500 keV/amy impact energy range. (paper)

  10. Microclima em vinhedos de 'Niagara rosada' em diferentes sistemas de condução durante safras de inverno e de verão

    Directory of Open Access Journals (Sweden)

    Mário José Pedro Júnior

    2013-03-01

    Full Text Available Na região vitícola de Jundiaí, o tradicional sistema de condução das plantas em espaldeira vem sendo paulatinamente substituído pela manjedoura na forma de Y. Alguns produtores têm lançado mão do uso de cobertura plástica para conferir maior proteção aos cachos de uva. Como esses diferentes sistemas de condução provocam alterações no microclima dos vinhedos, foram feitas medições de radiação solar global, umidade relativa, temperaturas máxima e mínima do ar no ambiente externo e na altura dos cachos de vinhedos de 'Niagara Rosada' conduzidos em espaldeira a céu aberto e em Y, com e sem cobertura de plástico, durante o período das safras de inverno e de verão. Verificou-se, que durante a safra de verão, as diferenças entre os valores diários de radiação solar, temperatura máxima do ar e umidade relativa foram mais elevadas em relação às da safra de inverno na comparação entre os sistemas de condução e o ambiente externo. Os vinhedos conduzidos em espaldeira apresentaram menores valores de radiação solar e umidade relativa do ar, na altura dos cachos. As temperaturas máximas e mínimas do ar foram semelhantes em todos os sistemas de condução e durante as diferentes safras. O uso de cobertura plástica no sistema de condução em Y não influiu na umidade relativa do ar e na temperatura mínima, porém propiciou aumento nos valores de temperatura máxima do ar.

  11. Thermal significance of potassium feldspar K-Ar ages inferred from /sup 40/Ar//sup 39/Ar age spectrum results

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, T.M.; McDougall, I. (Australian National Univ., Canberra. Research School of Earth Sciences)

    1982-10-01

    /sup 40/Ar//sup 39/Ar age spectrum analyses of three microcline separates from the Separation Point Batholith, northwest Nelson, New Zealand, which cooled slowly through the temperature zone of partial radiogenic /sup 40/Ar accumulation are characterized by a linear age increase over the first 65 percent of gas release with the lowest ages corresponding to the time that the samples cooled below about 100/sup 0/C. The last 35 percent of /sup 39/Ar released from the microclines yields plateau ages which reflect the different bulk mineral ages, and correspond to cooling temperatures between about 130 to 160/sup 0/C. Theoretical calculations confirm the likelihood of diffusion gradients in feldspars cooling at rates =< 5/sup 0/C-Ma/sup -1/. Diffusion parameters calculated from the /sup 39/Ar release yield an activation energy, E = 28.8 +- 1.9 kcal-mol/sup -1/, and a frequency factor/grain size parameter, D/sub 0//l/sup 2/ = 5.6sub(-3.9)sup(+14) sec/sup -1/. This Arrhenius relationship corresponds to a closure temperature of 132 +- 13/sup 0/C which is very similar to the independently estimated temperature. From the observed diffusion compensation correlation, this D/sub 0//l/sup 2/ implies an average diffusion half-width of about 3 ..mu..m, similar to the half-width of the perthite lamellae in the feldspars. The results are discussed.

  12. 40Ar-39Ar dating of hornfels dredged near the Japan trench

    International Nuclear Information System (INIS)

    Takigami, Yutaka; Fujioka, Kantaro

    1989-01-01

    During the KH 81-3 Cruise of the R/V Hakuho-Maru, biotite-bearing hornfelses were dredged from the landward slope of the Japan Trench. Bulk sample and separated biotite were dated by the 40 Ar- 39 Ar method and they showed 40 Ar- 39 Ar ages of 28.9±1.4 Ma and 28.5±1.4 Ma, respectively. This would indicate that biotite was formed at about 29 Ma by the thermal metamorphism which might have related with some magmatic activity. In this magmatic activity was caused by the subducting oceanic plate in the similar conditions at present, it seems to have occurred at a place too close to the present trench axis. This discrepancy could be explained by such processes as the change of the angle of the subducting plate, the moving of the trench axis by tectonic erosion and so on. However, more age data are required to solve this discrepancy. (author)

  13. 40Ar/39Ar and K/Ar whole rock age constraints on the timing of regional deformation, South Coast of New South Wales, Lachlan Fold Belt, Southeastern Australia: problems and implications

    International Nuclear Information System (INIS)

    Phillips, D.; Fergusson, C.L.

    1999-01-01

    Full text: Subduction complex rocks are well exposed on the south coast of New South Wales around Batemans Bay. Farther south in the Narooma and Bermagui region, Offier et al (1998) have determined two 40 Ar/ 39 Ar ages of 450 ± 3 Ma and 445 ± 2 Ma. They argued that these ages constrain the timing of intense underplating-related deformation and we have undertaken farther work, from an area south of Batemans Bay, to test this suggestion. The 40 Ar/ 39 Ar method applied to fine-grained, low temperature metamorphic rocks, such as slates, is beset by the problem of recoil loss and/or redistribution of 39 Ar during the irradiation process. Another problem is the difficulty of distinguishing between the contributions to 40 Ar/ 39 Ar spectra from illite/muscovite grown during the cleavage-producing deformation and detrital muscovite/illite. In the current study, four slate samples, with variable contents of detrital white mica, were analysed by both the K-Ar and 40 Ar/ 39 Ar step-heating methods. A separate of detrital white mica from one slate sample yields a plateau age of 500 ± 2 Ma. This result indicates that inheritance has not been eliminated by metamorphism as is commonly assumed and that the 40 Ar/ 39 Ar ages provide only a maximum estimate for the timing of deformation. 40 Ar/ 39 Ar analyses of state chips yield discordant, saddle-shaped age spectra, with minimum, within-saddle' ages of ca. 420 Ma. Two slate samples give identical 40 Ar/ 39 Ar integrated ages of 455 ± 2 Ma. One sample contains relatively abundant detrital bedding-parallel mica flakes that are locally oblique to the regional cleavage in the rock. The 40 Ar/ 39 Ar ages are some 20 Ma older than K-Ar ages for these same samples, suggesting that recoil loss of 39 Ar may also have affected these slates. Both recoil loss of 39 Ar and inherited white micas will yield elevated apparent ages, thus providing only maximum ages for the cleavage-producing deformation. Two other samples from slaty tectonic

  14. Androgen Receptor (AR) Physiological Roles in Male and Female Reproductive Systems: Lessons Learned from AR-Knockout Mice Lacking AR in Selective Cells1

    Science.gov (United States)

    Chang, Chawnshang; Lee, Soo Ok; Wang, Ruey-Sheng; Yeh, Shuyuan; Chang, Ta-Min

    2013-01-01

    ABSTRACT Androgens/androgen receptor (AR) signaling is involved primarily in the development of male-specific phenotypes during embryogenesis, spermatogenesis, sexual behavior, and fertility during adult life. However, this signaling has also been shown to play an important role in development of female reproductive organs and their functions, such as ovarian folliculogenesis, embryonic implantation, and uterine and breast development. The establishment of the testicular feminization (Tfm) mouse model exploiting the X-linked Tfm mutation in mice has been a good in vivo tool for studying the human complete androgen insensitivity syndrome, but this mouse may not be the perfect in vivo model. Mouse models with various cell-specific AR knockout (ARKO) might allow us to study AR roles in individual types of cells in these male and female reproductive systems, although discrepancies are found in results between labs, probably due to using various Cre mice and/or knocking out AR in different AR domains. Nevertheless, no doubt exists that the continuous development of these ARKO mouse models and careful studies will provide information useful for understanding AR roles in reproductive systems of humans and may help us to develop more effective and more specific therapeutic approaches for reproductive system-related diseases. PMID:23782840

  15. Prostate Cancer Cells Express More Androgen Receptor (AR) Following Androgen Deprivation, Improving Recognition by AR-Specific T Cells.

    Science.gov (United States)

    Olson, Brian M; Gamat, Melissa; Seliski, Joseph; Sawicki, Thomas; Jeffery, Justin; Ellis, Leigh; Drake, Charles G; Weichert, Jamey; McNeel, Douglas G

    2017-12-01

    Androgen deprivation is the primary therapy for recurrent prostate cancer, and agents targeting the androgen receptor (AR) pathway continue to be developed. Because androgen-deprivation therapy (ADT) has immmunostimulatory effects as well as direct antitumor effects, AR-targeted therapies have been combined with other anticancer therapies, including immunotherapies. Here, we sought to study whether an antigen-specific mechanism of resistance to ADT (overexpression of the AR) may result in enhanced AR-specific T-cell immune recognition, and whether this might be strategically combined with an antitumor vaccine targeting the AR. Androgen deprivation increased AR expression in human and murine prostate tumor cells in vitro and in vivo The increased expression persisted over time. Increased AR expression was associated with recognition and cytolytic activity by AR-specific T cells. Furthermore, ADT combined with vaccination, specifically a DNA vaccine encoding the ligand-binding domain of the AR, led to improved antitumor responses as measured by tumor volumes and delays in the emergence of castrate-resistant prostate tumors in two murine prostate cancer models (Myc-CaP and prostate-specific PTEN-deficient mice). Together, these data suggest that ADT combined with AR-directed immunotherapy targets a major mechanism of resistance, overexpression of the AR. This combination may be more effective than ADT combined with other immunotherapeutic approaches. Cancer Immunol Res; 5(12); 1074-85. ©2017 AACR . ©2017 American Association for Cancer Research.

  16. The 40Ar/39Ar and U/Pb dating of young rhyolites in the Kos-Nisyros volcanic complex, Eastern Aegean Arc, Greece: Age discordance due to excess 40Ar in biotite

    Science.gov (United States)

    Bachmann, O.; Schoene, B.; Schnyder, C.; Spikings, R.

    2010-08-01

    High-precision dating of Quaternary silicic magmas in the active Kos-Nisyros volcanic center (Aegean Arc, Greece) by both 40Ar/39Ar on biotite and U/Pb on zircon reveals a complex geochronological story. U/Pb ID-TIMS multi and single-grain zircon analyses from 3 different units (Agios Mammas and Zini domes, Kefalos Serie pyroclasts) range in age from 0.3 to 0.5 to 10-20 Ma. The youngest dates provide the maximum eruption age, while the oldest zircons indicate inheritance from local continental crust (Miocene and older). Step-heating 40Ar/39Ar experiments on 1-3 crystals of fresh biotite yielded highly disturbed Ar-release patterns with plateau ages typically older than most U/Pb ages. These old plateau ages are probably not a consequence of inheritance from xenocrystic biotites because Ar diffuses extremely fast at magmatic temperatures and ratios are reset within a few days. On the basis of (1) elevated and/or imprecise 40Ar/36Ar ratios, (2) shapes of the Ar release spectra, and (3) a high mantle 3He flux in the Kos-Nisyros area, we suggest that biotite crystals retained some mantle 40Ar that led to the observed, anomalously old ages. In contrast, sanidine crystals from the only sanidine-bearing unit in the Kos-Nisyros volcanic center (the caldera-forming Kos Plateau Tuff) do not appear to store any excess 40Ar relative to atmospheric composition. The eastern edge of the Aegean Arc is tectonically complex, undergoing rapid extension and located close to a major structural boundary. In such regions, which are characterized by high fluxes of mantle volatiles, 40Ar/39Ar geochronology on biotite can lead to erroneous results due to the presence of excess 40Ar and should be checked either against 40Ar/39Ar sanidine or U/Pb zircon ages.

  17. Acesso ao cuidado à saúde da criança em serviços de atenção primária

    Directory of Open Access Journals (Sweden)

    Rosane Meire Munhak da Silva

    2014-10-01

    Full Text Available Realizou-se uma pesquisa de abordagem qualitativa com base no referencial metodológico da hermenêutica dialética, com o objetivo de identificar o atributo acesso da atenção primária para a resolução dos problemas de saúde de crianças menores de um ano a partir dos relatos de pais e cuidadores. Envolveram-se 16 cuidadores de crianças atendidas em unidades de pronto atendimento de Cascavel-PR, em 2010. Foram reconhecidas quatro categorias temáticas: Aconselhamento familiar ao buscar atenção à saúde da criança; Ausência de acolhimento ao primeiro contato; Presença de classificação de risco para atenção à saúde da criança; Barreiras que impedem o acesso à atenção à saúde. Concluiu-se que as famílias exibiram dificuldades para alcançar resolutividade aos problemas de saúde dos filhos, mediante a falta de acesso aos serviços de atenção primária.

  18. Accurate and precise 40Ar/39Ar dating by high-resolution, multi-collection, mass spectrometry

    DEFF Research Database (Denmark)

    Storey, Michael; Rivera, Tiffany; Flude, Stephanie

    New generation, high resolution, multi-collector noble gas mass spectrometers equipped with ion-counting electron multipliers provide opportunities for improved accuracy and precision in 40Ar/39Ar dating. Here we report analytical protocols and age cross-calibration studies using a NU-Instruments......New generation, high resolution, multi-collector noble gas mass spectrometers equipped with ion-counting electron multipliers provide opportunities for improved accuracy and precision in 40Ar/39Ar dating. Here we report analytical protocols and age cross-calibration studies using a NU......-Instruments multi-collector Noblesse noble gas mass spectrometer configured with a faraday detector and three ion-counting electron multipliers. The instrument has the capability to measure several noble gas isotopes simultaneously and to change measurement configurations instantaneously by the use of QUAD lenses...... (zoom optics). The Noblesse offer several advantages over previous generation noble gas mass spectrometers and is particularly suited for single crystal 40Ar/39Ar dating because of: (i) improved source sensitivity (ii) ion-counting electron multipliers, which have much lower signal to noise ratios than...

  19. 40Ar/ 39Ar ages and paleomagnetism of São Miguel lavas, Azores

    Science.gov (United States)

    Johnson, Catherine L.; Wijbrans, Jan R.; Constable, Catherine G.; Gee, Jeff; Staudigel, Hubert; Tauxe, Lisa; Forjaz, Victor-H.; Salgueiro, Mário

    1998-08-01

    We present new 40Ar/ 39Ar ages and paleomagnetic data for São Miguel island, Azores. Paleomagnetic samples were obtained for 34 flows and one dike; successful mean paleomagnetic directions were obtained for 28 of these 35 sites. 40Ar/ 39Ar age determinations on 12 flows from the Nordeste complex were attempted successfully: ages obtained are between 0.78 Ma and 0.88 Ma, in contrast to published K-Ar ages of 1 Ma to 4 Ma. Our radiometric ages are consistent with the reverse polarity paleomagnetic field directions, and indicate that the entire exposed part of the Nordeste complex is of a late Matuyama age. The duration of volcanism across São Miguel is significantly less than previously believed, which has important implications for regional melt generation processes, and temporal sampling of the geomagnetic field. Observed stable isotope and trace element trends across the island can be explained, at least in part, by communication between different magma source regions at depth. The 40Ar/ 39Ar ages indicate that our normal polarity paleomagnetic data sample at least 0.1 Myr (0-0.1 Ma) and up to 0.78 Myr (0-0.78 Ma) of paleosecular variation and our reverse polarity data sample approximately 0.1 Myr (0.78-0.88 Ma) of paleosecular variation. Our results demonstrate that precise radiometric dating of numerous flows sampled is essential to accurate inferences of long-term geomagnetic field behavior. Negative inclination anomalies are observed for both the normal and reverse polarity time-averaged field. Within the data uncertainties, normal and reverse polarity field directions are antipodal, but the reverse polarity field shows a significant deviation from a geocentric axial dipole direction.

  20. Application of quadrupole mass spectrometer to the 40Ar-39Ar geochronological study

    International Nuclear Information System (INIS)

    Takigami, Yutaka; Nishijima, Tadashi; Koike, Toshio; Okuma, Kouichi.

    1984-01-01

    A Quadrupole Mass Spectrometer (QMS) has commonly been used for qualitative analyses of gases in organic chemistry or for monitoring the vacuum conditions in industrial machines. No attempt has been made, however, to apply it to geochronological studies because of its disadvantages such as the difficulty in obtaining precise isotope ratios due to triangular peak shapes and poor reproducibility. On the other hand, there are advantages that a QMS is relatively inexpensive and gives a shorter scanning time for analysis compared with a sector type mass spectrometer. The latter characteristics is useful for 40 Ar/ 39 Ar geochronological studies, since it gives a lower background in the QMS and the possibility to obtain many more data from one sample in a limited time. In this study, we have tried to improve a commercial QMS at many parts, such as rf-generator, quadrupole, ionization chamber, source magnet, and so on, in order to meet the requirements to use it for geochronological studies. With the use of the improved QMS equipped with an on-line microcomputer, we could obtain Ar isotope data which are sufficiently precise for the 40 Ar/ 39 Ar geochronological studies. (author)

  1. ARS-Media for excel instruction manual

    Science.gov (United States)

    ARS-Media for Excel Instruction Manual is the instruction manual that explains how to use the Excel spreadsheet ARS-Media for Excel application. ARS-Media for Excel Instruction Manual is provided as a pdf file....

  2. PADRÕES DE VARIABILIDADE EM VAZÕES AFLUENTES A USINAS HIDRELÉTRICAS E ASSOCIAÇÕES COM MASSAS DE AR

    Directory of Open Access Journals (Sweden)

    Erick Meira de Oliveira

    2018-03-01

    Full Text Available DOI: 10.12957/cadest.2017.31363 Os padrões fluviais brasileiros são sensíveis a diversos fatores geográficos e atmosféricos locais e de grande escala, sofrendo variações consideráveis ao longo da extensão territorial do País. Apesar da vasta gama de informações hoje disponíveis sobre esses fatores, sabe-se que a vazão de rios brasileiros possui relações significativas com padrões climáticos bem característicos, podendo se substituir, por vezes, uma quantidade expressiva de elementos por amostras que concentrem a maior parte das informações estatísticas da base de dados. Nesse contexto, este trabalho buscou identificar, por meio da aplicação de diferentes técnicas de análise estatística multivariada, características comuns a diferentes rios brasileiros, utilizando como informação principal suas vazões. Os resultados sugerem que os comportamentos de grande parte dos rios brasileiros usados para aproveitamento hidrelétrico podem ser caracterizados por um conjunto pequeno de padrões bem definidos, que traduzem os diferentes regimes de massas de ar aos quais o território brasileiro está submetido. Palavras-chave: Análise Multivariada; Vazões de Rios; Massas de ar.

  3. Microbial contamination of central supply systems for medical air Contaminação microbiana dos sistemas centrais de abastecimento de ar medicinal

    Directory of Open Access Journals (Sweden)

    Carolina Machado Andrade

    2003-11-01

    Full Text Available There are many standards and recommendations for breathing air quality associated with respiratory protection equipment, but little has been done regarding the possible microbial contamination of medical air. The present study demonstrates quantitatively and qualitatively that pipelines might be incriminated as source of microbial contamination of compressed and synthetic air for medical use. Air samples were drawn into an especially pressure-resistant device and the bacterial and fungi contents were identified after growth on agar plates. The bacterial flora isolated from peripheral air outlets was virtually the same as that found in the central air-generating installations, consisting of a mixture of pathogens and normal skin bacteria. Several factors contributing to microbial contamination of medical air are mentioned and preventive measures are discussed.Existem vários padrões e recomendações para a qualidade do ar respirável relacionado aos equipamentos de proteção respiratória, mas pouco tem sido feito em relação a uma possível contaminação microbiana do ar medicinal. O presente trabalho demonstra quantitativa e qualitativamente que as linhas de ar estão relacionadas à contaminação microbiológica do ar comprimido e ar sintético para uso medicinal. Amostras de ar foram coletadas por um equipamento especialmente resistente a pressão, e o conteúdo bacteriano e fúngico foi identificado após crescimento em placa. A flora bacteriana isolada tanto dos sistema periféricos de ar foi virtualmente a mesma encontrada nas instalações centralizadas, sendo uma mistura de patógenos e bactérias normais da pele. Vários fatores contribuintes para a contaminação microbiana do ar medicinal e medidas preventivas são discutidas.

  4. The thermal history of the Lhasa Block, South Tibetan Plateau based on FTD and Ar-Ar dating

    CERN Document Server

    Yang, T F; Lo Chong Huah; Chung, S L; Tien, R L; Xu, R; Deng, W

    1999-01-01

    Twelve basement samples were collected from South Tibet Plateau for FTD and Ar-Ar analysis to demonstrate their uplifting history since Cenozoic era. The preliminary results from different minerals with different closure temperatures, including apatite and zircon for fission-track dating, and K-feldspar, biotite for Ar-Ar dating, show that at least four stages of thermal history can be recognized in the studied area.

  5. The thermal history of the Lhasa Block, South Tibetan Plateau based on FTD and Ar-Ar dating

    International Nuclear Information System (INIS)

    Yang, T.F.; Wang, J.R.; Lo, C.H.; Chung, S.L.; Tien, R.L.; Xu, R.; Deng, W.

    1999-01-01

    Twelve basement samples were collected from South Tibet Plateau for FTD and Ar-Ar analysis to demonstrate their uplifting history since Cenozoic era. The preliminary results from different minerals with different closure temperatures, including apatite and zircon for fission-track dating, and K-feldspar, biotite for Ar-Ar dating, show that at least four stages of thermal history can be recognized in the studied area

  6. Diltiazem como alternativa ao betabloqueador na angiotomografia de artérias coronárias

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Rochitte

    2012-08-01

    Full Text Available FUNDAMENTO: A redução da frequência cardíaca (FC na angiografia por tomografia das artérias coronarianas (ATCCor é fundamental para a qualidade de imagem. A eficácia dos bloqueadores de cálcio como alternativas para pacientes com contraindicações aos betabloqueadores não foi definida. OBJETIVOS: Comparar a eficácia na redução da FC e variabilidade RR do metoprolol e diltiazem na ATCCor. MÉTODOS: Estudo prospectivo, randomizado, aberto, incluiu pacientes com indicação clínica de ATCCor, em ritmo sinusal, com FC>70bpm e sem uso de agentes que interferissem com a FC. Cinquenta pacientes foram randomizados para grupos: metoprolol IV 5-15 mg ou até FC≤60 bpm(M, e diltiazem IV 0,25-0,60mg/kg ou até FC≤60 bpm (D. Pressão arterial (PA e FC foram aferidas na condição basal, 1min, 3min e 5min após agentes, na aquisição e após ATCCor. RESULTADOS: A redução da FC em valores absolutos foi maior no grupo M que no grupo D (1, 3, 5min, aquisição e pós-exame. A redução percentual da FC foi significativamente maior no grupo M apenas no 1 min e 3 min após início dos agentes. Não houve diferença no 5 min, durante a aquisição e após exame. A variabilidade RR percentual do grupo D foi estatisticamente menor do que a do grupo M durante a aquisição (variabilidade RR/ FC média da aquisição. Um único caso de BAV, 2:1 Mobitz I, revertido espontaneamente ocorreu (grupo D. CONCLUSÃO: Concluímos que o diltiazem é uma alternativa eficaz e segura aos betabloqueadores na redução da FC na realização de angiografia por tomografia computadorizada das artérias coronarianas. (Arq Bras Cardiol. 2012; [online].ahead print, PP.0-0

  7. Forma urbana tradicional e modernista:

    Directory of Open Access Journals (Sweden)

    Dr. Arq. Antônio Tarcìsio da Luz Reis

    2014-12-01

    Full Text Available O objetivo deste artigo é refletir sobre algumas das implicações da forma urbana tradicional e da forma urbana modernista, para o uso e estética dos espaços ur banos, tais como a existência de conexões visuais e funcionais entre as edifca- ções e os espaços abertos públicos e o uso dado aos pavimentos térreos. Na "for ma urbana tradicional" as edifcações possuem portas frontais e janelas voltadas para as ruas públicas, enquanto na "forma urbana modernista" as edifcações ten dem a ter portas e janelas distantes das vias públicas e/ou voltadas para espaços abertos internos ao quarteirão, sem distinção entre portas e janelas frontais e pos teriores. Assim, exemplos de cidades em diferentes países são utilizados para as comparações e reflexões envolvendo estes aspectos. As principais consequências destas análises reforçam a necessidade de um melhor entendimento em relação às implicações da forma urbana para o uso e a estética dos espaços urbanos. Adi cionalmente, destaca–se a importância da existência de conexões visuais e fun cionais entre os térreos das edifcações e os espaços abertos públicos para a vi talidade, segurança e aparência dos espaços urbanos.

  8. Funcionalidade da oleoresina de páprica microencapsulada em goma-arábica e amido de arroz/gelatina.

    OpenAIRE

    SANTOS, A.B.; FÁVARO-TRINDADE, C.S.; GROSSO, C.R.F.

    2006-01-01

    O objetivo deste trabalho foi avaliar a funcionalidade da oleoresina de páprica microencapsulada em goma-arábica e amido de arroz/gelatina, incorporada nos sistemas-modelo bolo e gel de gelatina. Avaliou-se a cor por meio de medida instrumental e aceitação sensorial por atributos de aparência e aceitação global. O pigmento encapsulado solubilizou-se, tingiu e se distribuiu uniformemente nos bolos, os quais apresentaram boa aceitação global. Nos géis, a goma apresentou desempenho superior ao a...

  9. High-resolution 40Ar/39Ar chronology of multiple intrusion igneous complexes

    Science.gov (United States)

    Foland, K. A.; Chen, J.-F.; Linder, J. S.; Henderson, C. M. B.; Whillans, I. M.

    1989-06-01

    The Mount Brome complex of the Monteregian province of southern Quebec, Canada, consits of several major intrusions ranging compositionally from gabbro to syenite. The relative ages of these intrusives have been investigated with high-resolution 40Ar/39Ar analyses, including a specially designed irradiation configuration to cancel the effects of fluence gradients. Small yet distinct apparent age differences are observed. While a number of analytical and geological factors could be proposed to explain the small variations, evaluation of these suggests the age differences reflect those in emplacement times. The gabbro and nepheline diorite were emplaced within a short span 123.1 Ma ago. Generally more evolved lithologies (biotite monzodiorite, pulaskite, nordmarkite) appear to have been emplaced within a restricted interval 1.4±0.3 Ma later. Whole-rock Rb-Sr systematics do not give acceptable isochrons because of significant scatter interpreted to reflect initial 87Sr/86Sr heterogeneities resulting from crustal contamination. Considering the variations in initial ratio, the Rb-Sr data are consistent with the 40Ar/39Ar age.

  10. Fatores associados aos comportamentos de risco à saúde entre adolescentes brasileiros: uma revisão integrativa

    Directory of Open Access Journals (Sweden)

    Luciana Ramos de Moura

    2018-04-01

    Full Text Available RESUMO Objetivo: Identificar o conhecimento sobre fatores associados aos comportamentos de risco para a saúde entre adolescentes brasileiros. Método: Revisão integrativa da literatura nas bases de dados Cochrane, IBECS, LILACS, MEDLINE e SciELO, em relação aos comportamentos de risco recomendados pelo Centro de Controle e Prevenção de Doenças. Resultados: Analisaram-se 37 estudos, com predomínio do comportamento sexual de risco, uso do tabaco e comportamento violento. O avançar da idade favoreceu o sexo desprotegido, o uso do álcool e tabaco. A influência familiar e de amigos relacionou-se com tabagismo e alcoolismo. O sexo masculino envolveu-se mais em situações de violência e o sexo feminino associou-se à inatividade física. Pertencer a classes econômicas mais baixas relacionou-se com sexo desprotegido, inatividade física, comportamento alimentar não saudável e violência. Estudar em escola privada referiu-se ao comportamento alimentar não saudável. Conclusão: Comportamentos de risco relacionaram-se a fatores sociais, econômicos e familiares e tendem a se aglomerar.

  11. Developing a chronostratigraphic tool for climatic archives: absolute dating (K/Ar and 40Ar/39Ar) and paleo-magnetism applied to lavas

    International Nuclear Information System (INIS)

    Sasco, Romain

    2015-01-01

    The understanding of climatic mechanisms and rapid climate changes requires a high-resolution, robust, and precise timescale which allows long-distance and multi-archives correlations.An appropriate tool to construct such a timescale is provided by the Earth magnetic field (EMF). The EMF is independent from climatic variations and its past evolution, global at the surface of the Earth, is recorded by most of the geological/climatic archives. Sedimentary sequences provide continuous records of relative intensities of the EMF on timescales usually based on ice core age models or orbital tuning. Lavas, though discontinuously emitted through time, record the absolute intensity of the EMF during their cooling at the surface of the Earth. Lavas are dated using 2 complementary methods: 40 Ar/ 39 Ar and K-Ar, both independent from climatic parameters. Lavas have therefore the potential to deliver tie-points (age - paleo-intensity couples) enabling the time calibration of sedimentary sequences and their transfer onto absolute intensity scale and chronological time scale. This timescale can then be transferred to other climatic archives. The present study focusses on the last 200 ka with lavas sampled from young volcanoes of Ardeche (South Massif Central, France) and recent phases of volcanism in the Canary Islands. Lava flows from Ardeche provided un-exploitable paleo-intensity results and ages with large uncertainties. Therefore, they failed to provide suitable tie-points. However, our geochronological results evidence how crucial the combination of both the K-Ar and 40 Ar/ 39 Ar methods is to test the accuracy and geological meaning of the ages. Ardeche lavas have abundant mantellic and crustal xenoliths, potential carriers of excess 40 Ar*. Our study suggests that the argon excess is located in sites that decrepitate at low temperature (≤600 C). Because 40 Ar/ 39 Ar ages are not affected by excess 40 Ar*, they provide reliable results. The new age dataset indicates

  12. A refined astronomically calibrated 40Ar/39Ar age for Fish Canyon sanidine

    NARCIS (Netherlands)

    Rivera, T.A.; Storey, M.; Zeeden, C.; Hilgen, F.J.; Kuiper, K.

    2011-01-01

    Intercalibration between the astronomical and radio-isotopic dating methods provides a means to improving accuracy and reducing uncertainty of an integrated, multi-chronometer geologic timescale. Here we report a high-precision 40Ar/39Ar age for the FishCanyon sanidine (FCs) neutron fluence monitor,

  13. Call for Development of New Mineral Standards for 40Ar/39Ar Dating

    Science.gov (United States)

    Deino, A. L.; Turrin, B. D.; Renne, P. R.; Hemming, S. R.

    2015-12-01

    Age determination via the 40Ar/39Ar dating method relies on the intercomparison of measured 40Ar*/39ArK ratios of geological unknowns with those of co-irradiated mineral standards. Good analytical procedure dictates that these ratios (and the evolution of the Ar ion beams underpinning them) be as similar as practical for the greatest accuracy. Unfortunately, throughout several intervals of the geological time scale this 'best practice' cannot be achieved with existing widely used standards. Only two internationally utilized sanidine standards are available for the middle to late Cenozoic: the Alder Creek Rhyolite sanidine (ACs), at ~1.2 Ma (Turrin et al., 1994; Nomade et al., 2005), and the Fish Canyon Tuff sanidine (FCs) at ~28.2 Ma (e.g., Kuiper et al., 2008; Renne et al, 2011). The situation is even worse throughout much of the rest of the Phanerozoic, as the next oldest standard in common use is the Hb3gr hornblende standard with an age of ~1.1 Ga (Turner, 1971; Jourdan et al., 2006). We propose, as a community effort, the development a set of standards covering the entire target range of high-precision 40Ar/39Ar dating, i.e. the Phanerozoic. Their ages would be stepped in a regular fashion with no more than approximately a factor of 3 between standards, such that in the worse case the 40Ar*/39Ar ratios of standards and unknown need differ by no more than a factor of two. While somewhat arbitrary, an approximately 3 X age progression allows the entire time scale to be covered by a manageable number of standards. Anchoring the progression in the widely used ACs, FCs, and Hb3gr (in bold, below) yields the following set of suggested standard ages: 0.4, 1.2, 3.3, 9.4, 28.2, 95, 320, and 1100 Ma. A suitable standard should be highly reproducible in age at the grain-to-grain and sub-grain levels, and highly radiogenic. The mineral should be abundant and easily separated from the host rock. These criteria may be most easily achieved by focusing on sanidine phenocrysts

  14. Spectroscopic and electric dipole properties of Sr+Ar and SrAr systems including high excited states

    Science.gov (United States)

    Hamdi, Rafika; Abdessalem, Kawther; Dardouri, Riadh; Al-Ghamdi, Attieh A.; Oujia, Brahim; Gadéa, Florent Xavier

    2018-01-01

    The spectroscopic properties of the fundamental and several excited states of Sr+Ar and SrAr, Van der Waals systems are investigated by employing an ab initio method in a pseudo-potential approach. The potential energy curves and the spectroscopic parameters are displayed for the 1-10 2Σ+, 1-6 2Π and 1-3 2Δ electronic states of the Sr+Ar molecule and for the 1-6 1Σ+, 1-4 3Σ+, 1-3 1,3Π and 1-3 1,3Δ states of the neutral molecule SrAr. In addition, from these curves, the vibrational levels and their energy spacing are deduced for Σ+, Π and Δ symmetries. The spectra of the permanent and transition dipole moments are studied for the 1,3Σ+ states of SrAr, which are considered to be two-electron systems and 2Σ+ states of the single electron Sr+Ar ion. The spectroscopic parameters obtained for each molecular system are compared with previous theoretical and experimental works. A significant correlation revealed the accuracy of our results.

  15. Skolotāju uztvertā stresa saistība ar apmierinātību ar darbu

    OpenAIRE

    Dejus, Ilze

    2014-01-01

    Pētījuma „Skolotāju uztvertā stresa saistība ar apmierinātību ar darbu” mērķis, pamatojoties uz teorētisko analīzi, pētīt skolotāju uztvertā stresa saistību ar apmierinātību ar darbu. Pētījuma jautājumi: 1.Vai pastāv statistiski nozīmīga saistība starp skolotāju uztvertā stresa līmeni un apmierinātību ar darbu? 2.Vai pastāv statistiski nozīmīgas atšķirības starp Liepājas 15.vidusskolas un Grobiņas novada skolotāju uztvertā stresa līmeni un apmierinātību ar darbu? Aptaujāti 113 skolot...

  16. Empowerment in the community: the design of an open indicators system from participatory evaluation processes

    Directory of Open Access Journals (Sweden)

    Pere Soler Maso

    2014-06-01

    Full Text Available Existem inúmeras perspectivas e abordagens conceituais para Avaliação Participativa (AP e os significados e sentidos que esta pode ter. Em todos os casos envolve uma mudança de perspectiva em modelos de avaliação, considerando-se como um processo de aprendizagem individual e coletivo. Nas seguintes linhas se pretende avançar em averiguar de que maneira as aprendizagens geradas em processo de AP contribuem para o empoderamento das pessoas e comunidades que protagonizam tal avaliação. A contribuição que aqui se apresenta descreve o desenho e ensaio de um sistema aberto de indicadores de empoderamento que pretende evidenciar a aprendizagem que processos como a AP geram nas pessoas que a vivenciam. Se detectam variáveis e indicadores de empoderamento através da análise da literatura e a discussão com investigadores, técnicos e agentes comunitários. Estes indicadores são testados em três estudos de caso que nos permitem testar a sua utilidade: através de um questionário, da análise de conteúdo das atas e transcrições das sessões de AP e da realização de entrevistas semi-estruturadas aos membros dos grupos de AP. Se apresenta a lista geral de variáveis e indicadores de empoderamento entendido como um sistema aberto, como uma matriz geradora, na medida em que pode completar-se e contrastarse a partir das novas contribuições que surjam com a sua aplicação. A partir da contrastação bibliográfica foi validado a maioria dos indicadores propostos. O sistema propõe outros indicadores pouco habituais nas formulações realizadas até agora, mas foram validados através de estudos de caso. O material apresentado é considerado como um bom ponto de partida para futuras pesquisas, e uma ajuda para reforçar enormemente o discurso e o valor das ações socioeducativas e o trabalho comunitário.

  17. Combined U-Th/He and 40Ar/39Ar geochronology of post-shield lavas from the Mauna Kea and Kohala volcanoes, Hawaii

    Energy Technology Data Exchange (ETDEWEB)

    Aciego, S.M.; Jourdan, F.; DePaolo, D.J.; Kennedy, B.M.; Renne, P.R.; Sims, K.W.W.

    2009-10-01

    Late Quaternary, post-shield lavas from the Mauna Kea and Kohala volcanoes on the Big Island of Hawaii have been dated using the {sup 40}Ar/{sup 39}Ar and U-Th/He methods. The objective of the study is to compare the recently demonstrated U-Th/He age method, which uses basaltic olivine phenocrysts, with {sup 40}Ar/{sup 39}Ar ages measured on groundmass from the same samples. As a corollary, the age data also increase the precision of the chronology of volcanism on the Big Island. For the U-Th/He ages, U, Th and He concentrations and isotopes were measured to account for U-series disequilibrium and initial He. Single analyses U-Th/He ages for Hamakua lavas from Mauna Kea are 87 {+-} 40 ka to 119 {+-} 23 ka (2{sigma} uncertainties), which are in general equal to or younger than {sup 40}Ar/{sup 39}Ar ages. Basalt from the Polulu sequence on Kohala gives a U-Th/He age of 354 {+-} 54 ka and a {sup 40}Ar/{sup 39}Ar age of 450 {+-} 40 ka. All of the U-Th/He ages, and all but one spurious {sup 40}Ar/{sup 39}Ar ages conform to the previously proposed stratigraphy and published {sup 14}C and K-Ar ages. The ages also compare favorably to U-Th whole rock-olivine ages calculated from {sup 238}U - {sup 230}Th disequilibria. The U-Th/He and {sup 40}Ar/{sup 39}Ar results agree best where there is a relatively large amount of radiogenic {sup 40}Ar (>10%), and where the {sup 40}Ar/{sup 36}Ar intercept calculated from the Ar isochron diagram is close to the atmospheric value. In two cases, it is not clear why U-Th/He and {sup 40}Ar/{sup 39}Ar ages do not agree within uncertainty. U-Th/He and {sup 40}Ar/{sup 39}Ar results diverge the most on a low-K transitional tholeiitic basalt with abundant olivine. For the most alkalic basalts with negligible olivine phenocrysts, U-Th/He ages were unattainable while {sup 40}Ar/{sup 39}Ar results provide good precision even on ages as low as 19 {+-} 4 ka. Hence, the strengths and weaknesses of the U-Th/He and {sup 40}Ar/{sup 39}Ar methods are

  18. The mass of sup 3 sup 2 Ar and sup 3 sup 3 Ar for fundamental tests

    CERN Document Server

    Blaum, K; Beck, D; Bollen, G; Herfurth, F; Kellerbauer, A G; Kluge, H J; Sauvan, E; Schwarz, S

    2003-01-01

    Masses of the short-lived radionuclides sup 3 sup 2 Ar (T sub 1 sub / sub 2 = 98 ms) sup 3 sup 3 Ar (T sub 1 sub / sub 2 = 173 ms) have been determined with the Penning trap mass spectrometer ISOLTRAP. Relative uncertainties of 6.0 x 10 sup - sup 8 (delta m = 1.8 keV) and 1.4 x 10 sup - sup 8 (delta m = 0.44 keV), respectively, have been achieved. At present, these new mass data serve as the most stringent test of the quadratic form of the isobaricmultiplet mass equation IMME. Furthermore, the improved accuracy for the mass of sup 3 sup 2 Ar yields a better constraint on scalar contributions to the weak interaction. New mass values have also been measured for sup 4 sup 4 Ar and sup 4 sup 5 Ar, and a 20 sigma deviation for sup 4 sup 4 Ar from the literature value was found and interpreted.

  19. Quantum treatment of the Ar-HI photodissociation dynamics

    International Nuclear Information System (INIS)

    Lopez-Lopez, Sergio; Prosmiti, Rita; Garcia-Vela, Alberto

    2004-01-01

    A wave packet simulation of the ultraviolet photolysis dynamics of Ar-HI(v=0) is reported. Cluster photodissociation is started from two different initial states, namely, the ground van der Waals (vdW) and the first excited vdW bending state, associated with the Ar-I-H and Ar-H-I isomeric forms of the system, respectively. Formation of Ar-I radical products is investigated over the energy range of the cluster absorption spectrum. It is found that the yield of bound Ar-I radical complexes is typically 90%-100% and 70%-80% for the initial states associated with the Ar-I-H and Ar-H-I isomers, respectively. This result is in agreement with the experimentally observed time-of-flight spectrum of the hydrogen fragment produced after Ar-HI photodissociation. The high Ar-I yield is explained mainly by the small amount of energy available for the radical that is converted into internal energy in the photofragmentation process, which enhances the Ar-I survival probability. Quantum interference effects manifest themselves in structures in the angular distribution of the hydrogen fragment, and in pronounced rainbow patterns in the rotational distributions of the Ar-I radical

  20. Ao leitor sem medo

    Directory of Open Access Journals (Sweden)

    José Eisenberg

    2000-05-01

    Full Text Available O texto resenha Ao leitor sem medo, de Renato Janine Ribeiro (Belo Horizonte, UFMG, 1999.This text is a review of Ao leitor sem medo by Renato Janine Ribeiro (Belo Horizonte, UFMG, 1999

  1. Ars Baltica-verkoston puheenjohtajuus Suomeen Risto Ruohoselle

    Index Scriptorium Estoniae

    1999-01-01

    1990. a. loodud võrgustiku Ars Baltica sekretariaat (Ars Baltica Contact Point & Communication Center) tuleb Kielist Tallinnasse Eesti kultuuriministeeriumi kuni aastani 2002 (Suur-Karja 23). Ars Baltica (ühendus)

  2. ATENDIMENTO AO DEPENDENTE QUÍMICO NA ESTRATÉGIA SAÚDE DA FAMÍLIA

    Directory of Open Access Journals (Sweden)

    Joelma Amélia Muniz

    2010-01-01

    Full Text Available A estratégia saúde da família (ESF é a base para a estrutura desse tipo de atendimento, uma vez que proporciona ao profissional a possibilidade de conhecer o meio em que seu paciente está inserido e também propiciar mudanças nesse meio. O presente trabalho se propôs a refletir sobre a capacitação e habilidade do profissional de enfermagem, envolvido no processo de acolhimento, encaminhamentos e recuperação do dependente químico. Essa pesquisa baseou-se em revisão bibliográfica usando como material: artigos, periódicos, manuais, dissertação, sites e livros referentes ao tema. Percebeu-se que a capacitação e educação permanente dos profissionais envolvidos no processo da recuperação do dependente de substâncias psicoativas são de indiscutível importância. Identificou-se que, além de promover a capacitação a equipe, o chefe da equipe de enfermagem deve perceber quais são os profissionais que possuem maior afinidade com esse tipo de atendimento, para após isso, designar tais profissionais à essa tarefa, eassim, alcançar melhores resultados.

  3. Single grains, thermal histories, and the 40Ar/39Ar method

    International Nuclear Information System (INIS)

    Wright, Norrie

    1989-01-01

    A key part in unraveling the history of the physical evolution of the earth is knowledge of the earth's thermal history. 40 Ar/ 39 Ar step heating of mineral samples provides a means of defining a local thermal history. to do this accurately the challenge is to extract meaningful diffusion parameters from a mineral's Arrhenius plot. In the case of biotite single grains, where the laboratory release of argon is a complex process, this can be a difficult task. (12 refs., 5 figs.)

  4. 40Ar/39Ar ages of adularia from the Golden Cross, Neavesville, and Komata epithermal deposits, Hauraki Goldfield, New Zealand

    International Nuclear Information System (INIS)

    Mauk, J.L.; Hall, C.M.

    2004-01-01

    New 40 Ar/ 39 Ar ages of adularia from three epithermal vein deposits in the Hauraki Goldfield constrain when these deposits formed. Adularia from veins at Neavesville has 40 Ar/ 39 Ar plateau and isochron ages of 6.89 ± 0.02 and 6.86 ± 0.02 Ma, respectively, similar to the 40 Ar/ 39 Ar plateau and isochron ages of adularia from veins at Golden Cross of 6.96 ± 0.04 and 6.93 ± 0.03 Ma, respectively. In contrast, Komata mineralisation formed at 5.99 ± 0.02 to 6.07 ± 0.03 Ma, based on the 40 Ar/ 39 Ar isochron and plateau ages of the adularia in these veins, similar to the previously reported 6.0 Ma age of mineralisation at Waihi/Favona. These preliminary data suggest that mineralisation in the Hauraki Goldfields occurred episodically. (author). 19 refs., 3 figs., 1 tab

  5. HDR-Aggregate Read Service (ARS)

    Data.gov (United States)

    Department of Veterans Affairs — ARS is a SOAP web service exposed over HTTPS that provides an aggregated (report) view of HTH Survey, DMP and Census data stored in the HDR DB. ARS is deployed in...

  6. Ars Electronica tulekul / Rael Artel

    Index Scriptorium Estoniae

    Artel, Rael, 1980-

    2003-01-01

    6.-11. IX toimub Austrias Linzis "Ars Electronica" festival, mille teema on "Code - The Language of Our Time". Festivali kavast, osalejatest, ava-performance'ist "Europe - A Symphonic Vision", näitusest "Cyberarts 2003. Prix Ars Electronica"

  7. A compilation of {sup 40}Ar-{sup 39} and K-Ar ages: report 25

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, P A [Geological Survey of Canada, Ottawa, ON (Canada); Roddick, J C

    1997-12-31

    Twenty-three {sup 40}Ar-{sup 39}Ar age determinations (including two potassium-argon analyses) carried out by the Geological Survey of Canada are reported. Each age determination is accompanied by a description of the rock and mineral concentrate used; brief interpretative comments regarding the geological significance of each age are also provided where possible. The experimental procedures employed are described in outline. An index of all Geological Survey of Canada K-Ar age determinations published in this format has been prepared using NTS quadrangles as the primary reference. (author). 6 refs., 2 tabs., 1 fig.

  8. ^<40>Ar-^<39>Ar Age Studies for Tectonics of the Gondwana Land

    OpenAIRE

    Takigami, Yutaka; Sugiura, Naoji

    1997-01-01

    ^Ar-^Ar age studies have been performed for samples from Antarctica and India which were parts of the Gondwana land at Mesozoic and Paleozoic time in order to investigate their thermal history and tectonic movement. From the both areas, ages of about 500 Ma which have been considered to be the age of Pan-African Orogeny were obtained, which represents that this thermal event spread widely over the Gondwana land.

  9. Acesso aberto à informação científica: políticas e iniciativas governamentais Acceso abierto a la información científica: políticas e iniciativas gobernamentales

    Directory of Open Access Journals (Sweden)

    Adriana Rosecler Alcará

    2010-03-01

    Full Text Available Trata das políticas de acesso aberto à informação científica e das propostas de ação com ênfase para as iniciativas governamentais em diferentes países. Descreve as recomendações da Unesco e da IFLA. Identifica as principais iniciativas, ações e recomendações internacionais. Finaliza evidenciando peculiaridades de áreas e de formas de tratamento da questão nas políticas já estabelecidas.

  10. GPS-Based AR Games Development Potential

    Directory of Open Access Journals (Sweden)

    Gregorius Alvin Raditya Santoso

    2014-11-01

    Full Text Available The application of new technologies in a game is not a new thing. One example is the application of Augmented Reality (AR technology in game. Many people do not know the application of AR technology in game, although the application of this technology is able to produce a game with unique gameplay. In addition, since AR game is GPS-based, it offers new gaming experience, that is, playing outdoors in which the real world becomes the game arena. This advantage gives the AR technology a huge potential to be developed into a game

  11. Dignidade da pessoa humana e o décimo segundo camelo - sobre os limites da fundamentação de direitos

    Directory of Open Access Journals (Sweden)

    Sobottka, Emil Albert

    2008-01-01

    Full Text Available Dignidade da pessoa humana adquiriu em anos recentes um destaque como princípio fundamental a partir do qual são derivados direitos, considerados igualmente fundamentais. Com base na discussão provocada por Luhmann sobre recursos externos ao direito num sistema definido como operativamente fechado e cognitivamente aberto, o texto discute se a dignidade da pessoa humana consegue ocupar este lugar funcional

  12. Biblioteca escolar e os usuários especiais: o profissional da informação frente ao desafio da inclusão

    Directory of Open Access Journals (Sweden)

    Maria Antonieta Ribeiro Marcolino

    2017-04-01

    Full Text Available Desde a década de 1960 defende-se internacionalmente a promoção das mesmas condições de acesso ao conhecimento e exercício da cidadania a indivíduos de diversas etnias, classes sociais, níveis de instrução, necessidades especiais e deficiências. No Brasil, a questão dos direitos das pessoas com deficiência foi enfatizada a partir da Constituição de 1988, que em seus Artigos 206 e 208 dispõe a igualdade de acesso ao ensino para todos. Sendo as bibliotecas escolares uma extensão das instituições de ensino, também as abrangem as políticas de educação inclusiva. No cenário da inclusão na biblioteca escolar, a atuação do bibliotecário é fundamental, pois esse profissional é o responsável pelo acolhimento do usuário. Este trabalho tem por objetivo fazer uma observação sobre a presença de usuários especiais na biblioteca escolar, e o profissional da informação frente às adequações necessárias com relação ao ambiente, acervo e atendimento da biblioteca escolar, de modo a promover um espaço aberto a todos. Por se tratar de uma pesquisa exploratória, foi realizada a partir de revisão bibliográfica de livros, teses, artigos e sites relacionados com o tema abordado, no intuito de analisar o ponto de vista de vários autores, principalmente das áreas de Biblioteconomia e Pedagogia, a fim de obter referencial teórico para firmar as ideias propostas por este trabalho. Conclui-se que, com o esforço e empenho do profissional da informação, as bibliotecas escolares podem estabelecer parceria com outras instituições e criar atividades para dar os primeiros passos para a construção de um ambiente inclusivo sem depender exclusivamente das iniciativas de suas mantenedoras.

  13. Fraturas expostas: uma análise das pinturas de "Desconstruções," de Alan Fontes

    OpenAIRE

    Costa, Alexandre Rodrigues da

    2015-01-01

    Este artigo se propõe a analisar as pinturas da série Desconstruções, de 2014, do artista mineiro Alan Fontes, a partir dos conceitos de informe e heterogenia de Georges Bataille. Tais conceitos nos permitirão pensar em uma pintura que se detém de maneira crítica sobre a arquitetura, ao tratar a casa como lugar precário, aberto aos acidentes. A casa se constitui, nas pinturas de Alan Fontes, como um espaço de proliferação de sentidos, que se abre, através do dilaceramento, para a desordem, a ...

  14. 40Ar-39Ar age studies for tectonics of the Gondwana land

    International Nuclear Information System (INIS)

    Takigami, Yutaka; Sugiura, Naoji.

    1997-01-01

    40 Ar- 39 Ar age studies have been performed for samples from Antarctica and India which were parts of the Gondwana land at Mesozoic and Paleozoic time in order to investigate their thermal history and tectonic movement. From the both areas, ages of about 500 Ma which have been considered to be the age of Pan-African Orogeny were obtained, which represents that this thermal event spread widely over the Gondwana land. (author)

  15. Apmierinātības ar dzīvi saistība ar laika perspektīvu

    OpenAIRE

    Selga, Toms

    2013-01-01

    Pētījuma mērķis ir noskaidrot vai pastāv saistības starp apmierinātību ar dzīvi un laika perspektīvu. Tika sagaidīts, ka indivīdiem, kam izteiktākas pozitīvās pagātnes un tagadnes hedoniskā laika uztvere, apmierinātības ar dzīvi rezultāti būs augstāki, bet indivīdiem ar negatīvās pagātnes uztveri apmierinātības ar dzīvi rādītāji būs zemāki (Zhang & Howell, 2011). Lai to noskaidrotu, tika izmantota apmierinātības ar dzīvi aptauja (Satisfaction With Life Scale, SWLS, Diener, Emmons, Larsen,...

  16. A test of the 40Ar/39Ar age spectrum technique on some terrestrial materials

    Science.gov (United States)

    Lanphere, M.A.; Brent, Dalrymple G.

    1971-01-01

    40Ar/39Ar age spectra were determined for 10 terrestrial rock and mineral samples whose geologic history is known from independent evidence. The spectra for six mineral and whole rock samples, including biotite, feldspar, hornblende, muscovite, and granodiorite, that have experienced post-crystallization heating did not reveal the age of crystallization in any obvious way. Minima in the spectra, however, give reasonable maximum ages for reheating and high-temperature maxima can be interpreted as minimum crystallization ages. High-temperature ages of microcline and albite that have not been reheated are approximately 10% younger than the known crystallization age. Apparently there are no domains in these feldspars that have retained radiogenic 40Ar quantitatively. Spectra from two diabase samples that contain significant quantities of excess argon might mistakenly be interpreted as spectra from reheated samples and do not give the age of emplacement. The 40Ar/39Ar age spectrum technique may be a potentially valuable tool for the study of geologic areas with complex histories, but the interpretation of age spectra from terrestrial samples seems to be more difficult than suggested by some previous studies. ?? 1971.

  17. 244-AR Vault Interim Stabilization Project Plan

    International Nuclear Information System (INIS)

    LANEY, T.

    2000-01-01

    The 244-AR Vault Facility, constructed between 1966 and 1968, was designed to provide lag storage and treatment for the Plutonium-Uranium Extraction Facility (PUREX) tank farm sludges. Tank farm personnel transferred the waste from the 244-AR Vault Facility to B Plant for recovery of cesium and strontium. B Plant personnel then transferred the treatment residuals back to the tank farms for storage of the sludge and liquids. The last process operations, which transferred waste supporting the cesium/strontium recovery mission, occurred in April 1978. After the final transfer in 1978, the 244-AR facility underwent a cleanout. However, 2,271 L (600 gal) of sludge were left in Tank 004AR from an earlier transfer from Tank 241-AX-104. When the cleanout was completed, the facility was placed in a standby status. The sludge had been transferred to Tank 004AR to support Pacific Northwest National Laboratory [PNNL] vitrification work. Documentation of waste transfers suggests that a portion of the sludge may have been moved from Tank 004AR to Tank 002AR in preparation for transfer back to the AX Tank Farm; however, quantities of the sludge that were moved to Tank 002AR from that transfer must be estimated

  18. Dating method with /sup 39/Ar

    Energy Technology Data Exchange (ETDEWEB)

    Loosli, H H [Bern Univ. (Switzerland). Physikalisches Inst.

    1983-04-01

    The principles of a dating method based on the cosmic-ray-produced radioisotope /sup 39/Ar are given. Technical requirements such as background and standard gas samples and gas proportional counting systems are described. With samples extracted from Greenland ice it can be demonstrated that /sup 39/Ar ages agree with ages obtained by other methods. First results on ocean water samples show that with this isotope valuable information on ocean mixing and circulation can be expected. /sup 39/Ar results on groundwater samples disagree for some aquifers with conventional /sup 14/C ages; possible explanations are discussed, especially underground production of /sup 39/Ar.

  19. 40Ar-39Ar dating of terrestrial and exterrestrial materials. Basalts from the Japan Sea floor, Deccan Plateau and meteorites from Antarctica

    International Nuclear Information System (INIS)

    Kaneoka, Ichiro; Takigami, Yutaka.

    1994-01-01

    Through a series of 40 Ar- 39 Ar dating for terrestrial and exterrestrial samples, the results for basalts from the Japan Sea floor, Deccan Plateau and for meteorites from Antarctica give significant information concerning their formation histories. 40 Ar- 39 Ar ages of basalts from the Japan Sea floor give a constraint that the Japan Sea floor was formed at least 20 Ma. 40 Ar- 39 Ar ages for dyke samples from the Deccan Plateau indicate a possibility for the occurrence of a little younger ages than that of the main plateau formations by a few million years. Meteorites collected from Antarctica show some variable 40 Ar- 39 Ar ages reflecting their different thermal histories. (author)

  20. A radicalidade de Os Parceiros do Rio Bonito

    Directory of Open Access Journals (Sweden)

    Santos Luiz Antonio C.

    2002-01-01

    Full Text Available O livro Os parceiros do Rio Bonito traz uma contribuição admirável ao pensamento social brasileiro por sua relevância ético-política, como obra de denúncia política e crítica social; por sua contribuição formal ou estética, uma fina arquitetura da palavra e da argumentação sociológica e antropológica; e por sua contribuição metodológica, a pertinência do ato crítico aberto e pautado pela fluidez, em contraposição à adesão irrestrita a determinado aparato teórico. À atitude crítica associa-se a atitude mental de empatia pelo objeto, que se afasta de um frio e distante "sociologismo", mas, ao mesmo tempo, se recusa a atribuir-lhe as características que "gostaríamos" que tivesse, conforme a ideologia ou as crenças que partilhamos. A radicalidade dessa obra reside no espírito aberto para a "aventura sociológica", daí resultando a inexistência de "manifestos"ou "normas" de conduta. Todavia, Candido demarca os limites entre o espírito aberto à diversidade e à versatilidade no trato do fenômeno social, de um lado, e a adesão aventureira a um relativismo estéril, de outro. Finalmente, discute-se aqui a íntima relação entre a conduta intelectual do autor - sua postura ética diante do mundo acadêmico - e sua própria obra.

  1. Energy dependence of the reaction rate constants of Ar+, Ar++ and N2+ ions with Cl2

    International Nuclear Information System (INIS)

    Lukac, P.; Holubcik, L.; Morva, I.; Lindinger, W.

    2002-01-01

    Dry etching processes using low temperature plasmas in Cl 2 and in Cl 2 -noble gas or nitrogen mixtures are common in the manufacture of semiconductor devices, but their chemical mechanisms are often poorly understood. Results are given for the reaction rate constant measurements of Ar + , Ar ++ , N 2 + ions with chlorine as a function of mean relative kinetic energy. The experiments were performed by using the innsbruck flow drift tube (IFDT) apparatus. Measurements were done at various E/N values, where E is the electric field strength and N the buffer gas density in the drift section. The mean relative kinetic energy KE CM between the ions and the neutral chlorine Cl 2 was calculated using the Wanniers formula. It was found that The N 2 + , Ar + and Ar ++ positive ions react with chlorine Cl 2 very fast and the corresponding reaction rate coefficients depend on the mean relative kinetic energy. For the reaction of Ar - with Cl 2 , its reaction coefficient depends also on the buffer gas. It can imply the enhancement of Cl 2 + ions during etching of Si in the Ar/Cl 2 mixtures. (nevyjel)

  2. Support for the Astronomically Calibrated 40Ar/39Ar Age of Fish Canyon Sanidine

    DEFF Research Database (Denmark)

    Rivera, Tiffany; Storey, Michael; Zeeden, Christian

    2011-01-01

    al. (2008) determined an astronomically calibrated 40Ar/39Ar age of 28.201 0.046 Ma (2), relative to the indirect astronomically tuned Moroccan Melilla Basin Messâdit section. Here, we provide independent verification for the Kuiper, et al. (2008) FCs age using sanidines extracted from the A1 tephra...

  3. Microarea dating of mineral and rock. The application of technique by combining 40Ar/39Ar mass spectrometer with laser probe

    International Nuclear Information System (INIS)

    Hu Shiling; Dai Tongmo; Pu Zhiping

    1998-01-01

    The 40 Ar/ 39 Ar dating of probe technique by the continuous laser is successfully applied to determine the ages of microarea samples for mineral and whole rock, including the standard samples from internal and abroad, volcanical rock from westsouthern Antarctica and Green Pissolites of Guizhou. Isochron ages for volcanical rock to be excess or lost argon are accomplished by the whole fused, and for 'green Pisolites' not only by the whole fused, but also by the steps heat. All of which shows the significant geological ages. It would be exhibited the obvious advantage for dating some special samples to make the microarea 40 Ar/ 39 Ar dating technique by laser probe as compare with conventional K-Ar and 40 Ar/ 39 Ar methods

  4. 40Ar/39Ar age of the Rotoiti Breccia and Rotoehu Ash, Okataina Volcanic Complex, New Zealand, and identification of heterogeneously distributed excess 40Ar in supercooled crystals

    DEFF Research Database (Denmark)

    Flude, Stephanie; Storey, Michael

    2016-01-01

    Co-magmatic granitoid clasts erupted as part of the Rotoiti Ignimbrite (Rotoehu Tephra) contain euhedral K-feldspar and biotite crystals that protrude into miarolytic cavities and show textural evidence for growth in super-cooled conditions and are thus interpreted as growing during eruption. 40Ar...... that appear to be largely unaffected by excess 40Ar. This population gives a statistically robust weighted mean age of 47.4 ± 1.5 ka (1σ, n = 13) and an indistinguishable inverse isochron age of 50 ± 3 ka for this historically difficult to date eruption. The weighted mean age is significantly younger than...... previous age estimates of the Rotoiti eruption obtained by K/Ar and 40Ar/39Ar dating of bracketing lavas, but is indistinguishable from recent 14C and (U–Th)/He dates and estimates based on orbital tuning and sedimentation rates constrained by 14C ages....

  5. The ArDM experiment

    CERN Document Server

    Haranczyk, M; Badertscher, A; Boccone, V; Bourgeois, N; Bueno, A; Carmona-Benitez, M C; Chorowski, M; Creus, W; Curioni, A; Daw, E; Degunda, U; Dell'Antone, A; Droge, M; Epprecht, L; Haller, C; Horikawa, S; Kaufmann, L; Kisiel, J; Knecht, L; Laffranchi, M; Lagoda, J; Lazzaro, C; Lightfoot, P; Lozano, J; Lussi, D; Maire, G; Mania, S; Marchionni, A; Mavrokoridis, K; Melgarejo, A; Mijakowski, P; Natterer, G; Navas-Concha, S; Otiougova, P; Piotrowska, A; Polinski, J; de Prado, M; Przewlocki, P; Ravat, S; Regenfus, C; Resnati, F; Robinson, M; Rochet, J; Romero, L; Rondio, E; Rubbia, A; Scotto-Lavina, L; Spooner, N; Viant, T; Trawinski, A; Ulbricht, J; Zalewska, A

    2010-01-01

    The aim of the ArDM project is the development and operation of a one ton double-phase liquid argon detector for direct Dark Matter searches. The detector measures both the scintillation light and the ionization charge from ionizing radiation using two independent readout systems. This paper briefly describes the detector concept and presents preliminary results from the ArDM R&D program, including a 3 l prototype developed to test the charge readout system.

  6. O tratamento contábil do capital intelectual em empresas com valor de mercado superior ao valor contábil

    Directory of Open Access Journals (Sweden)

    Joel Marques de Oliveira

    2003-08-01

    Full Text Available Este artigo tem por objetivo sintetizar o resultado da pesquisa sobre o tratamento contábil que é aplicado ao capital intelectual, sob a ótica do processo de gestão, representado pelos conceitos e técnicas que são utilizados e que dão suporte à ação da administração, em empresas com valor de mercado superior ao valor contábil. Para atingir este propósito, o artigo consubstancia-se em uma pesquisa realizada em duas empresas de capital aberto, de Santa Catarina, que apresentam valor de mercado, considerado o valor das ações superior ao seu valor contábil. Observou-se que, embora as empresas pesquisadas possuam todas as características das organizações voltadas ao conhecimento e domínio tecnológico, o tratamento contábil do capital intelectual é algo ainda muito incipiente, e que, os critérios utilizados para mensurar, registrar e evidenciar as informações referentes ao capital humano, capital estrutural e capital de clientes, com vistas ao processo de gestão, é algo que ainda carece de uma sistematização, para que se possa refletir, por meio das demonstrações contábeis, alguma posição nesse sentido. Concluiu-se que as empresas pesquisadas, mesmo não possuindo as informações sistematizadas sobre as iniciativas de mensuração do capital intelectual, têm consciência da sua importância. No entanto, para que os gestores desses empreendimentos possam, efetivamente, utilizá-las como um diferencial competitivo no processo de gestão, as informações sistematizadas sobre o capital intelectual devem fazer parte dos relatórios gerados para a tomada de decisões.The objective of this article si to summarize the result of the research about the accounting treatment which is applied to the intellectual capital, through the management viewpoint, in companies with a market value superior than the accounting value. In order to reach this intention, the article is substantiated on a research carried out in two open

  7. The potential of AR-V7 as a therapeutic target.

    Science.gov (United States)

    Uo, Takuma; Plymate, Stephen R; Sprenger, Cynthia C

    2018-03-01

    The androgen receptor variant AR-V7 is gaining attention as a potential predictive marker for as well as one of the resistance mechanisms to the most current anti-androgen receptor (AR) therapies in castration-resistant prostate cancer (CRPC). Accordingly, development of next-generation drugs that directly or indirectly target AR-V7 signaling is urgently needed. Areas covered: We review proposed mechanisms of drug resistance in relation to AR-V7 status, the mechanisms of generation of AR-V7, and its transcriptome, cistrome, and interactome. Pharmacological agents that interfere with these processes are being developed to counteract pan AR and AR-V7-specific signaling. Also, we address the current status of the preclinical and clinical studies targeting AR-V7 signaling. Expert opinion: AR-V7 is considered a true therapeutic target, however, it remains to be determined if AR-V7 is a principal driver or merely a bystander requiring heterodimerization with co-expressed full-length AR or other variants to drive CRPC progression. While untangling AR-V7 biology, multiple strategies are being developed to counteract drug resistance, including selective blockade of AR-V7 signaling as well as inhibition of pan-AR signaling. Ideally anti-AR therapies will be combined with agents preventing activation and enrichment of AR negative tumor cells that are otherwise depressed by AR activity axis.

  8. Argon defect complexes in low energy Ar irradiated molybdenum

    International Nuclear Information System (INIS)

    Veen, A. van; Buters, W.T.M.; Kolk, G.J. van der; Caspers, L.M.; Armstrong, T.R.

    1982-01-01

    Thermal desorption spectrometry has been used to study the defects created in Mo irradiated along the direction with Ar ions ranging in energy from 0.1 to 2 keV. In addition to monitoring the release of the implanted Ar, additional information has been obtained by decoration of the defects with low energy helium and subsequent monitoring of the helium release. The studies show evidence that the Ar can be trapped in both substitutional sites and in a configuration in which the Ar is associated with vacancies (ArVsub(n), n >= 2). Most of the Ar implanted at high energy is released at approx. equal to 1500 K by thermal vacancy assisted diffusion. Argon trapped closer to the surface is released at lower temperatures via at least three different surface related release mechanisms. Additional results are presented on the interaction of self interstitial atoms (introduced by 100 eV Xe bombardment) with the Ar defects. Substitutional Ar is found to convert to interstitial Ar which seems to be mobile at room temperature. The Ar-vacancy complexes are found to be reduced to substitutional Ar. The results of atomistic calculations of the release mechanisms will also be presented. (orig.)

  9. Avaliação clínica e evolutiva de crianças em programa de atendimento ao uso de fórmulas para alergia à proteína do leite de vaca

    Directory of Open Access Journals (Sweden)

    Ana Laissa O. Aguiar

    2013-06-01

    Full Text Available OBJETIVO: Determinar características clínicas e evolutivas de crianças acompanhadas em programa de referência para fornecimento de fórmulas especiais para alergia ao leite de vaca. MÉTODOS: Estudo descritivo, realizado em amostra de conveniência, com 214 crianças até três anos, com diagnóstico clínico e/ou teste padronizado de provocação oral aberto, referenciadas ao Programa de Fórmulas para Alergia ao Leite de Vaca, em Hospital Universitário Pediátrico de Natal, Rio Grande do Norte (2007/2009. Avaliaram-se dados clínico-epidemiológicos e indicação de fórmulas (soja, hidrolisado ou aminoácido à consulta inicial, além de resposta clínica e evolução nutricional (Anthro-OMS 2006 após três meses. Aplicaram-se os testes do qui-quadrado e t pareado nas análises, considerando-se significante p<0,05. RESULTADOS: Ao primeiro atendimento, a média de idade foi de 9,0±6,9 meses. Manifestações digestórias foram observadas em 81,8%; cutâneas, em 36,9%; e respiratórias, em 23,8%. Escore Z do IMC <-2,0 desvios padrão (DP foi encontrado em 17,9% das crianças com sintomas digestórios isolados, em 41,7% em uso de leite de vaca e em 8,7% com outras fórmulas (p<0,01. Fórmula de proteína isolada de soja foi usada em 61,2%; hidrolisados, em 35,4%; e aminoácidos, em 3,3%. As médias de escore Z do IMC ao atendimento inicial e após três meses foram, respectivamente, -0,24±1,47DP e 0,00±1,26DP (p=0,251, quando em uso de soja, e -0,70±1,51DP e -0,14±1,36DP (p=0,322, em uso de hidrolisado. CONCLUSÕES: Manifestações digestórias da alergia ao leite de vaca foram preponderantes e determinaram maior comprometimento nutricional. As fórmulas de substituição ao leite de vaca mais utilizadas foram de proteína isolada de soja e hidrolisados proteicos. O uso de ambas foi importante para a manutenção do estado nutricional.

  10. Experimental system to measure excitation cross-sections by electron impact. Measurements for ArI and ArII

    International Nuclear Information System (INIS)

    Blanco, F.; Sanchez, J.A.; Aguilera, J.A.; Campos, J.

    1989-01-01

    An experimental set-up to measure excitation cross-section of atomic and molecular levels by electron impact based on the optical method is reported. We also present some measurements on the excitation cross-section for ArI 5p'(1/2)0 level, and for simultaneous ionization and excitation of Ar leading to ArII levels belonging to the 3p 4 4p and 3p 4 4d configurations. (Author)

  11. Reacções adversas aos antibacilares em doentes internados: Gravidade e factores de risco

    Directory of Open Access Journals (Sweden)

    Ana Sofia Vilariça

    2010-05-01

    édia do grupo de doentes com RA foi de 58,4 dias. Esta demora média apresentou diferenças estatisticamente significativas (p< 0,001 em relação à demora média dos doentes sem RA, que foi de 26 dias. Os fármacos mais implicados foram a isoniazida (62,2% e a rifampicina (51,9%. Dos 134 casos em que foi possível caracterizar a gravidade das RA, em 106 casos (79% houve necessidade de suspensão do fármaco. A relação causal fármaco-RA foi definitiva em 23 casos (17%. Dos 13 doentes (9,6% que faleceram, em 6 (4,4% a RA esteve directamente implicada na causa de morte.A ocorrência de qualquer RA foi associada ao alcoolismo (risco relativo [RR] de 3,0; 95% de intervalo confiança [IC], 1,1-7,9 e aos níveis de CD4 < 350 células/mm 3 ([RR] de 2,6; [IC], 1,4-5.No modelo preditivo, as reacções hepáticas foram associadas à ocorrência de hepatites virais B e/ou C ([RR] de 2,5; [IC], 1,2-5,1 e aos níveis de CD4 < 350 células/mm3 ([RR] de 5,5; [IC], 1,6-18,6.Conclusões: Os antibacilares estão associados a um número significativo de RA que podem condicionar grande morbilidade, prolongamento do internamento e mesmo alguma mortalidade. Os nossos resultados mostram que o alcoolismo e os níveis de CD4 <350 células/mm3 foram significativamente associados a um elevado risco de ocorrência de qualquer RA e que as hepatites B e C e os níveis de CD4 < 350 células/mm3 foram associados, também de forma significativa, ao risco de RA hepáticas.Rev Port Pneumol 2010; XVI (3: 431-451 Abstract: Introduction: Given Mycobacterium tuberculosis’s characteristics, the treatment of tuberculosis (TB infection is administered over a long period of time (for six months or more with a combination of several drugs which could cause adverse reactions (AR. These can cause significant morbidity and compromise tuberculosis treatment regimens.Aim: To determine the incidence and severity of and risk factors for major

  12. Reacções adversas aos antibacilares em doentes internados: Gravidade e factores de risco

    Directory of Open Access Journals (Sweden)

    Ana Sofia Vilariça

    2010-05-01

    média do grupo de doentes com RA foi de 58,4 dias. Esta demora média apresentou diferenças estatisticamente significativas (p < 0,001 em relação à demora média dos doentes sem RA, que foi de 26 dias. Os fármacos mais implicados foram a isoniazida (62,2% e a rifampicina (51,9%. Dos 134 casos em que foi possível caracterizar a gravidade das RA, em 106 casos (79% houve necessidade de suspensão do fármaco. A relação causal fármaco-RA foi definitiva em 23 casos (17%. Dos 13 doentes (9,6% que faleceram, em 6 (4,4% a RA esteve directamente implicada na causa de morte. A ocorrência de qualquer RA foi associada ao alcoolismo (risco relativo [RR] de 3,0; 95% de intervalo confiança [IC], 1,1–7,9 e aos níveis de CD4 < 350 células/ mm3 ([RR] de 2,6 ; [IC], 1,4–5. No modelo preditivo, as reacções hepáticas foram associadas à ocorrência de hepatites virais B e/ou C ([RR] de 2,5; [IC], 1,2–5,1 e aos níveis de CD4 < 350 células/mm3 ([RR] de 5,5; [IC], 1,6–18,6. Conclusões: Os antibacilares estão associados a um número significativo de RA que podem condicionar grande morbilidade, prolongamento do internamento e mesmo alguma mortalidade. Os nossos resultados mostram que o alcoolismo e os níveis de CD4 <350 células/mm3 foram significativamente associados a um elevado risco de ocorrência de qualquer RA e que as hepatites B e C e os níveis de CD4 < 350 células/mm3 foram associados, também de forma significativa, ao risco de RA hepáticas. Abstract: Introduction: Given Mycobacterium tuberculosis's characteristics, the treatment of tuberculosis (TB infection is administered over a long period of time (for six months or more with a combination of several drugs which could cause adverse reactions (AR. These can cause significant morbidity and compromise tuberculosis treatment regimens. Aim: To determine the incidence and severity of and risk factors for major

  13. Use of an A.E.I. MS 10 mass spectrometer for 40Ar-39Ar dating

    International Nuclear Information System (INIS)

    Baksi, A.K.

    1979-01-01

    The use of an AEI mass spectrometer for 40 Ar/ 39 Ar dating could, in principle, be problematical due to its limited mass resolution and because of non-linear mass discrimination under certain operating conditions. These possible drawbacks have been investigated and are found to be easy to overcome. Tailing corrections are relatively small and can be applied precisely for 40 Ar/ 39 Ar ratios <= 300. By operating the instrument with a trap current of 50 μA and an ion repeller voltage of +1.0 w.r.t. cage, problems due to non-linear mass discrimination are eliminated. Using the incremental heating technique and total fusion studies on very small subsamples (10-25 mg.), the homogeneity of some well-known inter-laboratory standards has been investigated; the relative merits of these standards are discussed. (K.B.)

  14. Avaliação de Coberturas de Cabanas de Maternidade em Sistema Intensivo de Suínos Criados ao Ar Livre (Siscal, no Verão Maternity Hut Covering Evaluation in Outdoor Pig Production System, Summer Data

    Directory of Open Access Journals (Sweden)

    Paulo Giovanni de Abreu

    2001-12-01

    Full Text Available O objetivo deste trabalho foi estudar as condições térmicas ambientais de diferentes materiais de cobertura de cabana de maternidade, no verão, utilizando os seguintes tratamentos: 1 cabana de maternidade coberta com fécula de isopor 2 cabana de maternidade coberta com isolamento de alumínio 3 cabana de maternidade coberta com tela e capim na cobertura 4 cabana de maternidade coberta com lona e capim na cobertura 5 ambiente ao ar livre e 6 à sombra da árvore. O delineamento experimental usado foi em blocos casualizados, em esquema de parcelas subdivididas, com 6 tratamentos nas parcelas, 5 horas nas subparcelas e 3 repetições. A categoria animal utilizada foi porcas lactantes, Landrace x Large White, distribuídas aleatoriamente por ordem de parto. Foi determinada a Umidade Relativa do Ar (UR, a Velocidade do Ar, a Temperatura Ambiente (Ta e foram calculados o Índice de Temperatura de Globo e Umidade (ITGU e a Carga Térmica Radiante (CTR. Apesar de os materiais utilizados como cobertura de maternidade terem melhorado o conforto térmico das porcas em relação as condições ambientais, ainda, não foram suficientes em atender as condições ideais de conforto térmico.The objective of this study was to evaluate the environmental thermal conditions of different maternity hut covering materials, in the summer period through the following treatments: 1 maternity hut with polystyrene fecula covering 2 maternity hut with isolation of aluminum covering 3 maternity hut with screen and grass covering 4 maternity hut with canvas and grass covering 5 outdoor environment 6 under shade a tree. The six treatments were arranged in a randomized split-plot design where the six treatments were in the plot with five schedules hours in the subplots and three replicates. Sow lactantes Landrace x Large White were alloted at random considering farrowing order. Relative Humidity Air (RH, Air Speed, and Environmental Temperature (Te data were determined

  15. MEIS1 functions as a potential AR negative regulator

    Energy Technology Data Exchange (ETDEWEB)

    Cui, Liang [Department of Urology, Chinese PLA Medical School/Chinese PLA General Hospital, Beijing 100853 (China); Department of Urology, Civil Aviation General Hospital/Civil Aviation Medical College of Peking University, Beijing 100123 (China); Li, Mingyang [Department of Gastroenterology, Nan Lou Division, Chinese PLA Medical School/Chinese PLA General Hospital, Beijing 100853 (China); Feng, Fan [Department of Pharmacy, General Hospital of Shenyang Military Command, Shenyang 110016 (China); Yang, Yutao [Beijing Institute for Neuroscience, Capital Medical University, Beijing 100069 (China); Hang, Xingyi [National Scientific Data Sharing Platform for Population and Health, Beijing 100730 (China); Cui, Jiajun, E-mail: cuijn@ucmail.uc.edu [Department of Cancer and Cell Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 (United States); Gao, Jiangping, E-mail: jpgao@163.com [Department of Urology, Chinese PLA Medical School/Chinese PLA General Hospital, Beijing 100853 (China)

    2014-10-15

    The androgen receptor (AR) plays critical roles in human prostate carcinoma progression and transformation. However, the activation of AR is regulated by co-regulators. MEIS1 protein, the homeodomain transcription factor, exhibited a decreased level in poor-prognosis prostate tumors. In this study, we investigated a potential interaction between MEIS1 and AR. We found that overexpression of MEIS1 inhibited the AR transcriptional activity and reduced the expression of AR target gene. A potential protein–protein interaction between AR and MEIS1 was identified by the immunoprecipitation and GST pull-down assays. Furthermore, MEIS1 modulated AR cytoplasm/nucleus translocation and the recruitment to androgen response element in prostate specific antigen (PSA) gene promoter sequences. In addition, MEIS1 promoted the recruitment of NCoR and SMRT in the presence of R1881. Finally, MEIS1 inhibited the proliferation and anchor-independent growth of LNCaP cells. Taken together, our data suggests that MEIS1 functions as a novel AR co-repressor. - Highlights: • A potential interaction was identified between MEIS1 and AR signaling. • Overexpression of MEIS1 reduced the expression of AR target gene. • MEIS1 modulated AR cytoplasm/nucleus translocation. • MEIS1 inhibited the proliferation and anchor-independent growth of LNCaP cells.

  16. MEIS1 functions as a potential AR negative regulator

    International Nuclear Information System (INIS)

    Cui, Liang; Li, Mingyang; Feng, Fan; Yang, Yutao; Hang, Xingyi; Cui, Jiajun; Gao, Jiangping

    2014-01-01

    The androgen receptor (AR) plays critical roles in human prostate carcinoma progression and transformation. However, the activation of AR is regulated by co-regulators. MEIS1 protein, the homeodomain transcription factor, exhibited a decreased level in poor-prognosis prostate tumors. In this study, we investigated a potential interaction between MEIS1 and AR. We found that overexpression of MEIS1 inhibited the AR transcriptional activity and reduced the expression of AR target gene. A potential protein–protein interaction between AR and MEIS1 was identified by the immunoprecipitation and GST pull-down assays. Furthermore, MEIS1 modulated AR cytoplasm/nucleus translocation and the recruitment to androgen response element in prostate specific antigen (PSA) gene promoter sequences. In addition, MEIS1 promoted the recruitment of NCoR and SMRT in the presence of R1881. Finally, MEIS1 inhibited the proliferation and anchor-independent growth of LNCaP cells. Taken together, our data suggests that MEIS1 functions as a novel AR co-repressor. - Highlights: • A potential interaction was identified between MEIS1 and AR signaling. • Overexpression of MEIS1 reduced the expression of AR target gene. • MEIS1 modulated AR cytoplasm/nucleus translocation. • MEIS1 inhibited the proliferation and anchor-independent growth of LNCaP cells

  17. SRAO: the first southern robotic AO system

    Science.gov (United States)

    Law, Nicholas M.; Ziegler, Carl; Tokovinin, Andrei

    2016-08-01

    We present plans for SRAO, the first Southern Robotic AO system. SRAO will use AO-assisted speckle imaging and Robo-AO-heritage high efficiency observing to confirm and characterize thousands of planet candidates produced by major new transit surveys like TESS, and is the first AO system to be capable of building a comprehensive several-thousand-target multiplicity survey at sub-AU scales across the main sequence. We will also describe results from Robo-AO, the first robotic LGS-AO system. Robo-AO has observed tens of thousands of Northern targets, often using a similar speckle or Lucky-Imaging assisted mode. SRAO will be a moderate-order natural-guide-star adaptive optics system which uses an innovative photoncounting wavefront sensor and EMCCD speckle-imaging camera to guide on faint stars with the 4.1m SOAR telescope. The system will produce diffraction-limited imaging in the NIR on targets as faint as mν = 16. In AO-assisted speckle imaging mode the system will attain the 30-mas visible diffraction limit on targets at least as faint as mν = 17. The system will be the first Southern hemisphere robotic adaptive optics system, with overheads an order of magnitude smaller than comparable systems. Using Robo-AO's proven robotic AO software, SRAO will be capable of observing overheads on sub-minute scales, allowing the observation of at least 200 targets per night. SRAO will attain three times the angular resolution of the Palomar Robo-AO system in the visible.

  18. Microbiologia do ar : monitorização do ar em ambiente hospitalar

    OpenAIRE

    Santos, Ana Carina Marques dos

    2008-01-01

    O complexo ambiente hospitalar requer atenção especial, para assegurar uma saudável qualidade do ar interior, protegendo assim os profissionais de saúde e utentes de infecções nosocomiais e de doenças ocupacionais. Embora seja amplamente reconhecido que a contaminação de um bloco operatório seja a principal responsável pela complicação de uma cirurgia, em Portugal, estudos sobre microbiologia do ar a nível hospitalar são escassos. O objectivo deste estudo é investigar a vari...

  19. Progress on using deuteron-deuteron fusion generated neutrons for 40Ar/39Ar sample irradiation

    Science.gov (United States)

    Rutte, Daniel; Renne, Paul R.; Becker, Tim; Waltz, Cory; Ayllon Unzueta, Mauricio; Zimmerman, Susan; Hidy, Alan; Finkel, Robert; Bauer, Joseph D.; Bernstein, Lee; van Bibber, Karl

    2017-04-01

    We present progress on the development and proof of concept of a deuteron-deuteron fusion based neutron generator for 40Ar/39Ar sample irradiation. Irradiation with deuteron-deuteron fusion neutrons is anticipated to reduce Ar recoil and Ar production from interfering reactions. This will allow dating of smaller grains and increase accuracy and precision of the method. The instrument currently achieves neutron fluxes of ˜9×107 cm-2s-1 as determined by irradiation of indium foils and use of the activation reaction 115In(n,n')115mIn. Multiple foils and simulations were used to determine flux gradients in the sample chamber. A first experiment quantifying the loss of 39Ar is underway and will likely be available at the time of the presentation of this abstract. In ancillary experiments via irradiation of K salts and subsequent mass spectrometric analysis we determined the cross-sections of the 39K(n,p)39Ar reaction at ˜2.8 MeV to be 160 ± 35 mb (1σ). This result is in good agreement with bracketing cross-section data of ˜96 mb at ˜2.45 MeV and ˜270 mb at ˜4 MeV [Johnson et al., 1967; Dixon and Aitken, 1961 and Bass et al. 1964]. Our data disfavor a much lower value of ˜45 mb at 2.59 MeV [Lindström & Neuer, 1958]. In another ancillary experiment the cross section for 39K(n,α)36Cl at ˜2.8 MeV was determined as 11.7 ± 0.5 mb (1σ), which is significant for 40Ar/39Ar geochronology due to subsequent decay to 36Ar as well as for the determination of production rates of cosmogenic 36Cl. Additional experiments resolving the cross section functions on 39K between 1.5 and 3.6 MeV are on their way using the LICORNE neutron source of the IPN Orsay tandem accelerator. Results will likely be available at the time of the presentation of this abstract. While the neutron generator is designed for fluxes of ˜109 cm-2s-1, arcing in the sample chamber currently limits the power—straightforwardly correlated to the neutron flux—the generator can safely be run at. Further

  20. Suscetibilidade do capim-colonião e de cultivares de milho ao flúor

    Directory of Open Access Journals (Sweden)

    Rimena Ramos Domingues

    2011-01-01

    Full Text Available A emissão de fluoretos à atmosfera oriunda da produção de superfosfatos e de cerâmica tem causado preocupação pelo efeito tóxico às plantas, contudo são poucos os estudos desenvolvidos acerca do problema com espécie de interesse econômico agrícola. Desenvolveu-se o estudo para avaliar o efeito do flúor (F atmosférico em plantas de capim-colonião e de cultivares de milho, utilizando como referência espécies bioindicadoras do tipo sensível e tolerante. As plantas foram expostas à contaminação pelo F atmosférico por curtos períodos durante 32 dias em sistema de nebulização com 0,16 mol L-1 de ácido fluorídrico no ambiente interno de uma câmara (~0,20 mmol m-3 de F, havendo um controle não exposto, com quatro repetições. A exposição das plantas ao F causou aumento da concentração do elemento nas folhas até 60 mg kg-1 para o capim-colonião, e entre 100 mg kg-1 nas folhas novas e 170 mg kg-1 nas folhas velhas para quatro cultivares de milho, o que demonstrou o efeito cumulativo do elemento no ambiente. Sintomas visuais da toxicidade foram observados nas plantas e se caracterizaram pela ocorrência de cloroses e necroses na lâmina foliar. O capim-colonião é uma espécie bastante sensível ao poluente no ar. As cultivares de milho DKB 390 e Ômega 8315 também são mais sensíveis ao F quando comparadas às AG7088 e 2B707. Os teores de clorofila a nas plantas foram mais afetados pelo F em relação aos teores de clorofila b.

  1. Editorial dos organizadores deste número 10.5007/1518-2924.2007v12nesp1piii

    Directory of Open Access Journals (Sweden)

    Ligia Maria Arruda Café

    2007-12-01

    Full Text Available A comunicação científica tradicional enfrenta uma série de barreiras que dificultam não apenas a publicação dos resultados de pesquisas, como também o seu acesso por parte da comunidade científica. Entre essas dificuldades, destacam-se: 1 alta excessiva no custo das assinaturas de revistas científicas; 2 longo prazo para a efetiva publicação de determinado artigo; 3 os direitos autorais são entregues gratuitamente aos editores científicos, os únicos a ganhar em toda a cadeia da comunicação científica. A convergência tecnológica propiciou alternativas que podem derrubar parte dessas barreiras. Uma das alternativas que as tecnologias da informação e da comunicação propiciaram é o modelo de interoperabilidade denominado Arquivos Abertos (Open Archives. Em conseqüência, surge o movimento em prol do acesso livre à informação científica (Open Access. A experiência da conjugação dessa base tecnológica com o movimento do Acesso Livre à Informação Científica é o tema deste número especial da revista Encontros Bibli. As contribuições de especialistas brasileiros e estrangeiros para esta edição trazem um enfoque variado sobre este tema. Iniciamos com uma entrevista com Stevan Harnad, um dos principais líderes do movimento do Acesso Livre à Informação Científica. Nessa entrevista, Stevan comenta sobre o papel do modelo de interoperabilidade Open Archives no movimento Acesso Livre à Informação Científica, falando sobre o futuro desse movimento e as suas estratégias para implantar o acesso livre à informação científica em todo o planeta. O artigo “Comunicação científica: o papel da Open Archives Initiative no contexto do Acesso livre” aborda a questão do acesso livre, relacionando-a ao uso de tecnologias de auto-arquivamento e à publicação em periódicos eletrônicos que seguem a filosofia dos arquivos abertos como uma reação aos editores científicos comerciais. Apresenta as principais

  2. Ar + NO microwave plasmas for Escherichia coli sterilization

    International Nuclear Information System (INIS)

    Hueso, Jose L; Rico, Victor J; Cotrino, Jose; Gonzalez-Elipe, Agustin R; Frias, Jose E

    2008-01-01

    Ar + NO microwave discharges are used for sterilization and the results are compared with additional experiments with Ar, O 2 and N 2 -O 2 plasma mixtures. The NO * species produced in the Ar-NO mixtures remain up to long distances from the source, thus improving the sterilization efficiency of the process. E. coli individuals exposed to the Ar + NO plasma undergo morphological damage and cell lysis. Combined effects of etching (by O * and Ar * species) and UV radiation (from deactivation of NO * species) are responsible for the higher activity found for this plasma mixture. (fast track communication)

  3. Tibetan tectonics from 40Ar/39Ar analysis of a single K-feldspar sample

    International Nuclear Information System (INIS)

    Richter, F.M.; Lovera, O.M.; Harrison, T.M.; Copeland, P.

    1991-01-01

    40 Ar/ 39 Ar data on an alkali feldspar sample from the Quxu pluton, Gangdese batholith, southern Tibet, allow a detailed assessment of unroofing and uplift history between 35 and 18 Ma. The 39 Ar Arrhenius plot for this sample shows departures from a linear relationship between the effective diffusion parameter, log(D/r 2 ), and reciprocal temperature, which we interpret to be the result of a distribution of distinct diffusion-domain sizes. We use an alternative way of plotting the Arrhenius data that exhibits domain size versus cumulative % 39 Ar released during step heating. The 40 Ar/ 39 Ar age spectrum of the sample has features, such as local age plateaus, that are most easily explained in terms of the distinctive closure age of particular domains. The fact that the same distribution of diffusion-domain sizes explains both the Arrhenius data and the age spectrum is an indication that the diffusion properties operating in the laboratory are those of the sample while it was in its natural environment. Modelling of the age spectrum with a distribution of domain sizes results in the recovery of a continuous cooling-history segment rather than a single time-temperature datum. We demonstrate the robustness of the cooling-curve determination by showing the large misfits to the age spectrum that arise from relatively small changes in the cooling history. The best-fit cooling curve for the Quxu sample shows a decreasing rate of cooling in the time interval 35-18 Ma, followed by a very rapid cooling beginning at about 18 Ma. We have used a thermal model for the conductive cooling of an unroofing pluton to estimate the rate of unroofing required to explain the Quxu cooling curve, and find that in the 35-20 Ma time interval, the primary control of the thermal evolution is the conductive loss of magmatic heat with little or no unroofing (unroofing rates of approximately 0.05 mm/yr) followed by a brief period (<5 Ma) of very rapid unroofing with rates of order 2 mm

  4. In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and KRAS Point Mutations in Circulating Tumor Cells.

    Science.gov (United States)

    El-Heliebi, Amin; Hille, Claudia; Laxman, Navya; Svedlund, Jessica; Haudum, Christoph; Ercan, Erkan; Kroneis, Thomas; Chen, Shukun; Smolle, Maria; Rossmann, Christopher; Krzywkowski, Tomasz; Ahlford, Annika; Darai, Evangelia; von Amsberg, Gunhild; Alsdorf, Winfried; König, Frank; Löhr, Matthias; de Kruijff, Inge; Riethdorf, Sabine; Gorges, Tobias M; Pantel, Klaus; Bauernhofer, Thomas; Nilsson, Mats; Sedlmayr, Peter

    2018-03-01

    Liquid biopsies can be used in castration-resistant prostate cancer (CRPC) to detect androgen receptor splice variant 7 (AR-V7), a splicing product of the androgen receptor. Patients with AR-V7-positive circulating tumor cells (CTCs) have greater benefit of taxane chemotherapy compared with novel hormonal therapies, indicating a treatment-selection biomarker. Likewise, in those with pancreatic cancer (PaCa), KRAS mutations act as prognostic biomarkers. Thus, there is an urgent need for technology investigating the expression and mutation status of CTCs. Here, we report an approach that adds AR-V7 or KRAS status to CTC enumeration, compatible with multiple CTC-isolation platforms. We studied 3 independent CTC-isolation devices (CellCollector, Parsortix, CellSearch) for the evaluation of AR-V7 or KRAS status of CTCs with in situ padlock probe technology. Padlock probes allow highly specific detection and visualization of transcripts on a cellular level. We applied padlock probes for detecting AR-V7, androgen receptor full length (AR-FL), and prostate-specific antigen (PSA) in CRPC and KRAS wild-type (wt) and mutant (mut) transcripts in PaCa in CTCs from 46 patients. In situ analysis showed that 71% (22 of 31) of CRPC patients had detectable AR-V7 expression ranging from low to high expression [1-76 rolling circle products (RCPs)/CTC]. In PaCa patients, 40% (6 of 15) had KRAS mut expressing CTCs with 1 to 8 RCPs/CTC. In situ padlock probe analysis revealed CTCs with no detectable cytokeratin expression but positivity for AR-V7 or KRAS mut transcripts. Padlock probe technology enables quantification of AR-V7, AR-FL, PSA, and KRAS mut/wt transcripts in CTCs. The technology is easily applicable in routine laboratories and compatible with multiple CTC-isolation devices. © 2017 American Association for Clinical Chemistry.

  5. Estudos sôbre a conservação de sementes. IV - Café Influence of moisture content on the viability of coffee seeds

    Directory of Open Access Journals (Sweden)

    Oswaldo Bacchi

    1958-01-01

    Full Text Available Sementes de café, recém-colhidas e imediatamente sêcas à sombra e ao sol, foram conservadas com diferentes teores de umidade em dois tipos de recipientes, abertos e hermèticamente fechados, à temperatura não controlada do laboratório. Pelos resultados obtidos através de determinações periódicas das porcentagens de germinação e umidade das sementes armazenadas nessas condições, foram tiradas as seguintes conclusões: a a vitalidade das sementes foi inteiramente independente do processo de seca; b a longevidade das sementes conservadas em recipientes hermèticamente fechados foi inversamente proporcional ao seu teor de umidade; sementes com aproximadamente 20%, 13% e 10% de umidade premaneceram viáveis durante 4, 8 e 21 meses, respectivamente. c o teor inicial de umidade não teve qualquer influência sôbre a longevidade das sementes armazenadas em recipientes abertos; isto se verificou, provavelmente, em virtude da quantidade relativamente pequena de sementes, o que permitiu uma rápida desidratação daquelas que se encontravam com teores elevados de umidade; a vitalidade das sementes colocadas nestes recipientes permaneceu inalterada por oito a dez meses. Estas conclusões estão inteiramente em desacôrdo com as de vários autores, segundo as quais a semente de café perde rapidamente sua vitalidade pela simples desidratação ao ar.Freshly harvested seeds of coffee (Coffea arabica L. var. typica Cramer were air dried and sun-dried at different levels of moisture content and stored in open and sealed containers at room temperature. Moisture determination and germination tests were made on the "fresh" seeds and at different intervals during the storage period. Based on the results obtained, the following conclusions were drawn: 1 The process of drying did not interfere with the seed viability. 2 The longevity of the seeds kept in sealed containers was inversely proportional to the seed moisture content. Seeds containing about

  6. A eficácia do milnaciprano em pacientes ambulatoriais com transtorno depressivo maior não respondedores ao tratamento com ISRSs: um estudo aberto de 12 semanas Efficacy of milnacipran in outpatients experiencing major depression non respondent to SSRIs: a 12-week open study

    Directory of Open Access Journals (Sweden)

    Marcelo P. Fleck

    2010-01-01

    Full Text Available CONTEXTO: O objetivo deste estudo é avaliar a eficácia do milnaciprano em pacientes ambulatoriais com depressão maior grave que não respondem em tempo e em dosagem adequados à terapia com ISRSs. MÉTODOS: Um estudo aberto multicêntrico com a duração de 12 semanas foi elaborado para avaliar a eficácia do milnaciprano após falha em um experimento com ISRS. Remissão completa (HAMD-17 50%, CGI e avaliação da qualidade de vida (WHOQOL-Bref. RESULTADOS: O escore HAMD-17 médio da amostra foi de 27 (7,2. As taxas de remissão com o milnaciprano foram de 17,5%, e as de resposta, 61,3%. Na linha de base, 70,9% dos pacientes foram classificados como gravemente sintomáticos. Ao final do tratamento, 48,1% dos pacientes foram classificados como normais assintomáticos ou sintomáticos limítrofes e 20,2% eram moderadamente sintomáticos. Além disso, os quatro domínios do WHOQOL-Bref, um instrumento genérico de mensuração de qualidade de vida, apresentou diferenças clínicas e estatísticas: CONCLUSÃO: Nossos resultados sugerem que o milnaciprano é uma possível opção para pacientes que não respondem a ISRSs. Uma vez que não há evidências na literatura de um antidepressivo que seja a melhor opção quando um ISRS falha, o uso do milnaciprano deveria ser considerado em casos de pacientes com depressão severa.BACKGROUND: The objective of this study is to evaluate the efficacy of milnacipran in outpatients experiencing severe MDD non-respondent to adequate time and dosing of SSRI therapy. METHODS: A 12 week multi-centric study open study was designed to evaluate the efficacy of milnacipran after a SRRI trial failure. Complete remission (HAMD-17 50%, CGI and quality of life measure (WHOQOL-Bref. RESULTS: The mean HAMD-17 score of the sample was 27 (7.2. The remission rates for minalcipran were 17.5% and response 61.3%. At baseline, 70.9% of the patients were markedly or severely ill. At treatment end, 48.1% of the patients were normal

  7. Ar + NO microwave plasmas for Escherichia coli sterilization

    Energy Technology Data Exchange (ETDEWEB)

    Hueso, Jose L; Rico, Victor J; Cotrino, Jose; Gonzalez-Elipe, Agustin R [Instituto de Ciencia de Materiales de Sevilla, Centro Mixto CSIC-Universidad de Sevilla, Centro de Investigaciones Cientificas Isla de la Cartuja, Avda. Americo Vespucio 49, 41092 Sevilla (Spain); Frias, Jose E [Instituto de BioquImica Vegetal y FotosIntesis (IBVF-CSIC). Centro de Investigaciones CientIficas Isla de la Cartuja. Avda Americo Vespucio, 49, 41092 Sevilla (Spain)], E-mail: jhueso@icmse.csic.es

    2008-05-07

    Ar + NO microwave discharges are used for sterilization and the results are compared with additional experiments with Ar, O{sub 2} and N{sub 2}-O{sub 2} plasma mixtures. The NO{sup *} species produced in the Ar-NO mixtures remain up to long distances from the source, thus improving the sterilization efficiency of the process. E. coli individuals exposed to the Ar + NO plasma undergo morphological damage and cell lysis. Combined effects of etching (by O{sup *} and Ar{sup *} species) and UV radiation (from deactivation of NO{sup *} species) are responsible for the higher activity found for this plasma mixture. (fast track communication)

  8. Identification of an IL-1-induced gene expression pattern in AR+ PCa cells that mimics the molecular phenotype of AR- PCa cells.

    Science.gov (United States)

    Thomas-Jardin, Shayna E; Kanchwala, Mohammed S; Jacob, Joan; Merchant, Sana; Meade, Rachel K; Gahnim, Nagham M; Nawas, Afshan F; Xing, Chao; Delk, Nikki A

    2018-06-01

    In immunosurveillance, bone-derived immune cells infiltrate the tumor and secrete inflammatory cytokines to destroy cancer cells. However, cancer cells have evolved mechanisms to usurp inflammatory cytokines to promote tumor progression. In particular, the inflammatory cytokine, interleukin-1 (IL-1), is elevated in prostate cancer (PCa) patient tissue and serum, and promotes PCa bone metastasis. IL-1 also represses androgen receptor (AR) accumulation and activity in PCa cells, yet the cells remain viable and tumorigenic; suggesting that IL-1 may also contribute to AR-targeted therapy resistance. Furthermore, IL-1 and AR protein levels negatively correlate in PCa tumor cells. Taken together, we hypothesize that IL-1 reprograms AR positive (AR + ) PCa cells into AR negative (AR - ) PCa cells that co-opt IL-1 signaling to ensure AR-independent survival and tumor progression in the inflammatory tumor microenvironment. LNCaP and PC3 PCa cells were treated with IL-1β or HS-5 bone marrow stromal cell (BMSC) conditioned medium and analyzed by RNA sequencing and RT-QPCR. To verify genes identified by RNA sequencing, LNCaP, MDA-PCa-2b, PC3, and DU145 PCa cell lines were treated with the IL-1 family members, IL-1α or IL-1β, or exposed to HS-5 BMSC in the presence or absence of Interleukin-1 Receptor Antagonist (IL-1RA). Treated cells were analyzed by western blot and/or RT-QPCR. Comparative analysis of sequencing data from the AR + LNCaP PCa cell line versus the AR - PC3 PCa cell line reveals an IL-1-conferred gene suite in LNCaP cells that is constitutive in PC3 cells. Bioinformatics analysis of the IL-1 regulated gene suite revealed that inflammatory and immune response pathways are primarily elicited; likely facilitating PCa cell survival and tumorigenicity in an inflammatory tumor microenvironment. Our data supports that IL-1 reprograms AR + PCa cells to mimic AR - PCa gene expression patterns that favor AR-targeted treatment resistance and cell survival. © 2018 Wiley

  9. 75 FR 12165 - Class E Airspace; Batesville, AR

    Science.gov (United States)

    2010-03-15

    ...-1177; Airspace Docket No. 09-ASW-34] Class E Airspace; Batesville, AR AGENCY: Federal Aviation... Class E airspace at Batesville, AR. Decommissioning of the Independence County non-directional beacon... for standard instrument approach procedures at Batesville Regional Airport, Batesville, AR. Airspace...

  10. 37Ar monitoring techniques and on-site inspection system

    International Nuclear Information System (INIS)

    Duan Rongliang; Chen Yinliang; Li Wei; Wang Hongxia; Hao Fanhua

    2001-01-01

    37 Ar is separated, purified and extracted from air sample with a low temperature gas-solid chromatographic purifying method, prepared into a radioactive measurement source and its radioactivity is measured with a proportional counter. Based on the monitoring result, a judgement can be made if an nuclear explosion event has happened recently in a spectabilis area. A series of element techniques that are associated the monitoring of the trace element 37 Ar have been investigated and developed. Those techniques include leaked gas sampling, 37 Ar separation and purification, 37 Ar radioactivity measurement and the on-site inspection of 37 Ar. An advanced 37 Ar monitoring method has been developed, with which 200 liters of air can be treated in 2 hours with sensitivity of 0.01 Bq/L for 37 Ar radioactivity measurement. A practical 37 Ar On-site Inspection system has been developed. This research work may provide technical and equipment support for the verification protection, verification supervision and CTBT verification

  11. Formation of doubly charged argon ions, Ar2+, from long-lived highly excited argon ions, Arsup(+*), colliding with Ar and N2 gases

    International Nuclear Information System (INIS)

    Okuno, Kazuhiko

    1976-01-01

    Formation of Ar 2+ from long-lived highly excited Ar + * colliding with Ar and N 2 gases is studied by means of a tandem mass spectrometer. The tandem mass spectrometer used consists of two mass analyzers connected in series and a collision chamber located in between. The collision chamber is electrically floated and can be set at a desired potential, so that one can identify the fast ions (resulting from the primary ions) and the slow ions (secondary ions) in the mass spectra taken by the second mass analyzer. When the first mass analyzer is tuned to Ar + , peaks corresponding Ar 2+ appear in the second mass spectra. From the analysis of variation of mass positions and heights of these peaks with the change of the potential and pressure of the collision chamber, the Ar 2+ is concluded to result from the primary Ar + in collision with gas molecules and wall surface. From the threshold behavior of the product Ar 2+ with the electron energy in the ion source, three sets of long-lived highly excited Ar + * states (Rydberg states) are found to be responsible for this process. They are 3s 2 3p 4 ( 3 P)nl, 3s 2 3p 4 ( 1 D 2 )n'l and 3s 2 3p 4 ( 1 S 0 )n''l converging to Ar 2+3 Psub(2.1.0) (43.38, 43.51, 43.57 eV), 1 D 2 (45.11 eV) and 1 S 0 (47.50 eV), respectively. Their fractional ratio in the primary Ar + beam is determined as 3.0:1.0:1.2 which is close to that of multiplicities of the states concerned. The autoionization mechanism reported by other investigators to be responsible for the formation of Ar 2+ in Aston band or tandem mass spectra is found to be negligible. The cross sections of formation of Ar 2+ from Ar + * colliding with Ar and N 2 increase in proportion to the 1.15th power of the collision energy in the range from 750 eV to 2.5 keV. At the collision energy of 1.0 keV, they are 2.0x10 -20 /F cm 2 for Ar target and 6.6x10 -20 /F cm 2 for N 2 target, where the fractional density of Ar + * is estimated to be 0.7x10 -4 -4 . (auth.)

  12. I-Xe and 40Ar-39Ar analyses of silicate from the Eagle Station pallasite and the anomalous iron meteorite Enon

    International Nuclear Information System (INIS)

    Niemeyer, S.

    1983-01-01

    Silicate from two unusual iron-rich meteorites were analyzed by the I-Xe and 40 Ar- 39 Ar techniques. Enon, an anomalous iron meteorite with chondritic silicate, shows no loss of radiogenic 40 Ar at low temperature, and gives a plateau age of 4.59 +- 0.03 Ga. Although the Xe data fail to define an I-Xe correlation the inferred Pu/U ratio is more than 2 σ above the chondritic value, and the Pu abundance derived from the concentration of Pu-fission Xe is 6 times greater than the abundance inferred for CI meteorites. These findings for Enon, coupled with data for IAB iron meteorites, suggest that presence of chondritic silicate in an iron-rich meteorite is diagnostic of an old radiometric age with little subsequent thermal disturbance. The Eagle Station pallasite, the most 16 O-rich meteorite known, gives a complex 40 Ar- 39 Ar age pattern which suggests a recent severe thermal disturbance. The absence of excess 129 Xe, and the low trapped Ar and Xe contents, are consistent with this interpretation. The similarity between 40 Ar- 39 Ar data for Eagle Station and for the olivine-rich meteorite Chassigny lends credence to the previous suggestion of a connection between Chassigny and pallasites. (author)

  13. Efeito da velocidade do ar em barra de pulverização na deposição de produtos fitossanitários em feijoeiro Efect of the air speed in air-assisted sprayer on bean crop pesticide spray deposition

    Directory of Open Access Journals (Sweden)

    Carlos Gilberto Raetano

    2003-01-01

    Full Text Available Com o objetivo de avaliar o efeito da variação da velocidade do ar em barra de pulverização na deposição da calda na cultura do feijoeiro (Phaseolus vulgaris, realizou-se o experimento em 9 e 10 de outubro de 2000, no Centro de Pesquisas Agronômicas - Cyanamid, em Iracemápolis (SP, em delineamento inteiramente casualizado, aos 48 dias após a emergência (DAE. Para isso, convencionou-se que a rotação máxima do ventilador, medida com o auxílio de fototacômetro, possibilitou a obtenção da velocidade máxima do ar na barra de pulverização e, a partir daí, níveis de 50% e 75% da velocidade máxima do ar. Alvos artificiais foram fixados na superfície adaxial e na abaxial de folíolos posicionados, nos terços superior e inferior das plantas selecionadas, ao acaso, e distribuídas perpendicularmente ao deslocamento do pulverizador. O óxido cuproso (50% de cobre metálico foi o traçador utilizado em pulverização e a determinação quantitativa dos depósitos feita com o uso da espectrofotometria de absorção atômica. Os resultados sugerem que a variação da velocidade do ar na barra pulverizadora não influenciou sobre os níveis de depósitos no feijoeiro, aos 48 DAE, nas condições do presente trabalho.The aim of this research was to evaluate the effects of air speed in air-assisted sprayer on bean crop (Phaseolus vulgaris spray deposition. The experiment was carried out at 48 days after crop emergence and the experimental design was randomized. The maximum air speed in spray boom was obtained with the maximum of the fan rotation by a phototachometer. The middle and third air speed were obtained with lower fan rotation. The tracer used in the spray solution was copper oxid (50% of the metalic copper. It was measured by atomic spectrophotometry absorption equipment. The targets were fixed on the under and upper-side of the leaves, in the top and lower third of the same plant under the spray boom. The effects of variation

  14. Near thermal charge transfer between Ar+2 and N2

    International Nuclear Information System (INIS)

    Holzscheiter, H.M.; Church, D.A.

    1981-01-01

    The near thermal charge transfer reaction of Ar +2 with N 2 has been studied at total pressures below 10 -7 Torr using a stored ion technique. Ar +2 ions produced by electron impact double ionization of Ar gas were selectively stored for times the order of seconds in a split-ring Penning-type ion trap. The decay with time of the initial ion sample number in a mixture of Ar and N 2 gases was fit to the sum of two exponentials, corresponding to different reaction rates for the 3 P and 1 D low-lying Ar +2 levels. The observed Ar +2 number decrease is attributed to the double-charge transfer process Ar +2 +N 2 →Ar+N 2 +2 →Ar+N + +N + in accord with recent flow-tube measurements. A rate constant for the metastable Ar +2 ( 1 D) level reaction with a value k( 1 D)=1.4 x 10 -9 cm 3 /sec is obtained, using the previously measured rate constant for the Ar +2 ( 3 P) state

  15. Laser-fusion 40Ar/39Ar Ages of Darwin Impact Glass

    Science.gov (United States)

    Lo, Ching-Hua; Howard, Kieren T.; Chung, Sun-Lin; Meffre, Sebastien

    2002-11-01

    Three samples of Darwin Glass, an impact glass found in Tasmania, Australia at the edge of the Australasian tektite strewn field were dated using the 40Ar/39Ar single-grain laser fusion technique, yielding isochron ages of 796-815 ka with an overall weighted mean of 816 ± 7 ka. These data are statistically indistinguishable from those recently reported for the Australasian tektites from Southeast Asia and Australia (761-816 ka; with a mean weighted age of 803 ± 3 ka). However, considering the compositional and textural differences and the disparity from the presumed impact crater area for Australasian tektites, Darwin Glass is more likely to have resulted from a distinct impact during the same period of time.

  16. Ar-37 in the Atmospheric and Sub-Soil Gases

    International Nuclear Information System (INIS)

    Purtschert, R.; Raghoo, L.S.

    2015-01-01

    On-site inspection of the radioactive noble gas isotope 37Ar is a definitive and unambiguous indicator of an underground nuclear explosion. 37Ar is produced underground by neutron activation of calcium by the reaction 40Ca(n,α)37Ar. In the atmosphere, 37Ar is produced by the spallation reaction 40Ar(n,4n)37Ar. Periodic measurements over the last six years on air collected in Bern revealed a background level in the order of 1-5 mBq/m 3 air in agreement with former findings and theoretical calculations. Those calculations also indicated that the intrusion of stratospheric air masses may lead to elevated tropospheric 37Ar concentrations up to 8-10 mBq/m 3 air. Selected samples taken up to now in the vicinity of nuclear power plants revealed no significant deviation from the natural background. In order to distinguish between natural and artificially elevated 37Ar the location-specific 37Ar activity range in soils, rocks and the atmosphere were identified. From CARIBIC flights, a passenger aircraft with a special air freight container filled with scientific equipment in the cargo compartment, tropospheric air samples were analyzed for 37Ar and 85Kr. The natural 37Ar production in soils and the rock basement underlying the alluvium is investigated by means of in situ measurements of different isotopes, theoretical calculations and irradiation experiments on selected rock samples. This will help resolve the temporal evolution and/or constancy of the natural 37Ar background and allow for an interpretation in terms of the identification of clandestine nuclear explosions. (author)

  17. Bases para utilização de métodos e recursos abertos no Ensino

    OpenAIRE

    Fernandes, Pedro

    2013-01-01

    Está em curso um movimento global de abertura de recursos educativos aliada à exporação das potencialidades didáticas que emergem das visões conectivistas da aprendizagem. Como há cada vez mais adultos a aprender em todos os sectores da sociedade e como as transformações sociais estão trazer ao ensino formal pessoas que tradicionalmente só procuravam ensino informal, a busca de soluções que se adaptem ao adulto está a encontrar cada vez mais utilidade nos conceitos e práticas andragógicas que...

  18. Comportamento do meloeiro em cultivo sem solo com a utilização de biofertilizante

    Directory of Open Access Journals (Sweden)

    Villela Junior Luiz Vitor E.

    2003-01-01

    Full Text Available O reaproveitamento de nutrientes após a fermentação de resíduos orgânicos em biodigestor, associado à técnica do cultivo hidropônico, é uma alternativa para reduzir custos na agricultura, além de contribuir no menor consumo das reservas naturais de nutrientes do planeta. Com esse enfoque, estudou-se o comportamento da cultura do meloeiro usando a técnica hidropônica e efluente de biodigestor proveniente da fermentação anaeróbica de estrume bovino. Cultivou-se o meloeiro (Cucumis melo L. 'Bônus 2' em condições de ambiente protegido. O delineamento estatístico utilizado foi de blocos casualizados, com 4 tratamentos (cultivo hidropônico em sistema fechado tipo NFT com uso de solução nutritiva organo-mineral; cultivo hidropônico em sistema fechado tipo NFT com uso de solução nutritiva 100% mineral; cultivo em sistema aberto, com substrato e solução nutritiva organo-mineral e cultivo em sistema aberto, com substrato e solução nutritiva 100% mineral e 6 repetições. Foram realizadas avaliações quanto a altura de plantas aos 50; 56; 63; 70 e 77 dias após a semeadura; tempo de colheita; peso de frutos e produtividade. As melhores respostas foram observadas no cultivo hidropônico em sistema fechado tipo NFT com uso de solução nutritiva 100% mineral. A substituição parcial de adubos minerais por biofertilizante, se mostrou viável para os tratamentos em sistema aberto (com substrato, constituindo-se em masi uma alternativa aos horticultores.

  19. Targeting AR Variant-Coactivator Interactions to Exploit Prostate Cancer Vulnerabilities.

    Science.gov (United States)

    Magani, Fiorella; Peacock, Stephanie O; Rice, Meghan A; Martinez, Maria J; Greene, Ann M; Magani, Pablo S; Lyles, Rolando; Weitz, Jonathan R; Burnstein, Kerry L

    2017-11-01

    Castration-resistant prostate cancer (CRPC) progresses rapidly and is incurable. Constitutively active androgen receptor splice variants (AR-Vs) represent a well-established mechanism of therapeutic resistance and disease progression. These variants lack the AR ligand-binding domain and, as such, are not inhibited by androgen deprivation therapy (ADT), which is the standard systemic approach for advanced prostate cancer. Signaling by AR-Vs, including the clinically relevant AR-V7, is augmented by Vav3, an established AR coactivator in CRPC. Using mutational and biochemical studies, we demonstrated that the Vav3 Diffuse B-cell lymphoma homology (DH) domain interacted with the N-terminal region of AR-V7 (and full length AR). Expression of the Vav3 DH domain disrupted Vav3 interaction with and enhancement of AR-V7 activity. The Vav3 DH domain also disrupted AR-V7 interaction with other AR coactivators: Src1 and Vav2, which are overexpressed in PC. This Vav3 domain was used in proof-of-concept studies to evaluate the effects of disrupting the interaction between AR-V7 and its coactivators on CRPC cells. This disruption decreased CRPC cell proliferation and anchorage-independent growth, caused increased apoptosis, decreased migration, and resulted in the acquisition of morphological changes associated with a less aggressive phenotype. While disrupting the interaction between FL-AR and its coactivators decreased N-C terminal interaction, disrupting the interaction of AR-V7 with its coactivators decreased AR-V7 nuclear levels. Implications: This study demonstrates the potential therapeutic utility of inhibiting constitutively active AR-V signaling by disrupting coactivator binding. Such an approach is significant, as AR-Vs are emerging as important drivers of CRPC that are particularly recalcitrant to current therapies. Mol Cancer Res; 15(11); 1469-80. ©2017 AACR . ©2017 American Association for Cancer Research.

  20. Desempenho, variáveis fisiológicas e comportamento de bezerros mantidos em diferentes instalações: época seca Performance, physiological and behavioral measurements of dairy calves in different housing systems: dry season

    Directory of Open Access Journals (Sweden)

    Daniel de Noronha Figueiredo Vieira da Cunha

    2007-08-01

    Full Text Available Objetivou-se neste estudo avaliar o desempenho, o conforto térmico e o comportamento de bezerros mestiços Holandês × Zebu mantidos em abrigos móveis, sob sombrites ou a céu aberto durante a época seca do ano (26/04/2002 a 30/08/2002. Foram utilizados 24 bezerros do nascimento aos 70 dias de idade, distribuídos em blocos casualizados, nas instalações: 1 - abrigos móveis; 2 - sob telas de polipropileno (sombrite; 3 - a céu aberto. Os animais mantidos a céu aberto apresentaram, à tarde, maior temperatura retal e maior frequência respiratória. Não foram observadas diferenças entre intalações quanto às variáveis relacionadas ao comportamento animal. Bezerros mantidos em abrigos móveis passaram a maior parte do tempo fora das instalações. O desempenho dos animais não diferiu entre os tratamentos. Nos três tipos de instalação, os bezerros intensificaram, à tarde, os mecanismos latentes de perda de calor elevando a frequência respiratória acima da faixa considerada normal. Os animais mantidos a céu aberto não conseguem manter a temperatura retal na faixa considerada normal. Bezerros mantidos em abrigos móveis, sob telas de polipropileno ou a céu aberto apresentam desempenhos semelhantes.The objective of this trial was to evaluate performance, thermal comfort and behavior of crossbred Holstein x Zebu dairy calves kept in different housing systems during the dry season (26/04/2002 to 30/08/2002. Twenty-four calves were raised from birth to 70 days of age in one of the following housing systems: (1 - hutches; 2 - shadecloth; or 3 - with no shelter. Calves raised with no shelter showed higher rectal temperatures and respiratory rates in the afternoon. It was also observed that calves spend most of the time outside the hutches. There were no differences among housing systems for behavior measurements as well as for body weight, average daily weight gain, starter intake, and feed efficiency. In all three housing systems

  1. 75 FR 12162 - Class E Airspace; Manila, AR

    Science.gov (United States)

    2010-03-15

    ...-1184; Airspace Docket No. 09-ASW-39] Class E Airspace; Manila, AR AGENCY: Federal Aviation... Class E airspace at Manila, AR. Decommissioning of the Manila non-directional beacon (NDB) at Manila... instrument approach procedures at Manila Municipal Airport, Manila, AR. Airspace reconfiguration is necessary...

  2. Ecomorfologia de caranguejos e siris (Crustacea Decapoda Brachyura) de ecossistemas costeiros

    OpenAIRE

    Marochi, Murilo Zanetti

    2012-01-01

    Resumo: Ecomorfologia de caranguejos e siris (CRUSTACEA DECAPODA BRACHYURA) de ecossistemas costeiros. O presente estudo objetivou avaliar se diferentes espécies de Brachyura possuem padrões ecomorfológicos em comum ligados ao habitat em que estão inseridas. Foram analisados 528 exemplares pertencentes a 24 espécies e provenientes dos seguintes ecossistemas costeiros: manguezal, costão rochoso, praia arenosa, bentopelagial e mar aberto. De todos os exemplares foram mensurada...

  3. agradecimento aos consultores ad hoc

    Directory of Open Access Journals (Sweden)

    REA Editor

    2012-02-01

    Full Text Available Agradecemos aos professores Nildo Viana (UFG e Flavio Sofiati (UFG, organizadores do DOSSIÊ JUVENTUDE & SOCIEDADE, e aos Consultores Ad hoc pela leitura e apreciação crítica dos artigos submetidos e publicados nesta edição.

  4. Combate ao niilismo e ao totalitarismo em Camus

    Directory of Open Access Journals (Sweden)

    Emanuel Ricardo Germano

    2013-05-01

    Full Text Available A partir de uma leitura da peça Calígula, elaborada entre 1941 e 1943, procurar-se-á contribuir na restituição das preocupações éticas, políticas e filosóficas em cena no teatro de Albert Camus, analisando o sentido de sua expressão teatral no contexto de dois combates,ao niilismo filosófico e ao totalitarismo político de seu tempo. Observaremos em Calígula um importante registro do amadurecimento das leituras de duas heranças filosóficas relevantes na formação intelectual de Camus, Nietzsche e Heráclito, à luz da experiência do totalitarismo, observando e ressaltando com isso a amplitude de seu intertexto filosófico e a importância do aporte ético e político de Camus como pensador multifacetado, engajado nos enfrentamentos históricos e solicitações críticas de seu tempo.

  5. Efeitos ambientais da produção de suínos ao ar livre: evolução e distribuição espacial das formas de P no solo e perdas de P na água de drenagem Environmental impact of outdoor pig production: soil P forms evolution spatial distribution and P losses in drainage waters

    Directory of Open Access Journals (Sweden)

    Carmo Horta

    2012-06-01

    Full Text Available A produção de suínos ao ar livre é considerada pelos consumidores como um modo de produção mais amigo do ambiente e do bem-estar animal. No entanto, os nutrientes contidos na ração e no "excreta" dos suínos são continuamente introduzidos no solo conduzindo a aumentos significativos desses nutrientes no solo, em especial do fósforo (P. Esta continua adição de P ao solo pode exceder a sua capacidade de retenção originando perdas significativas de P para as águas de drenagem e de escoamento superficial, contribuindo para a poluição difusa das águas superficiais. O principal objectivo deste trabalho foi avaliar o impacto da produção de suínos ao ar livre sobre o teor em P do solo avaliando a sua distribuição espacial e temporal, e avaliar também a perda de P através das águas de drenagem interna do solo. A unidade experimental de produção de suínos ao ar livre deste trabalho tem 2.8 ha, um declive entre 5 e 30% e uma carga animal de 9 adultos / ha. Observou-se um aumento do P do solo, quer do P biodisponível (P Olsen, P-Ol quer do P inorgânico (Pi ou orgânico (Po. No Inverno observaram-se elevadas perdas de P por erosão e escoamento superficial, mas ao longo do tempo observou-se um aumento global do P no solo. Um teor em P-Ol > 20 mg kg-1 originou um aumento significativo na perda de P para as águas de drenagem interna. Melhores práticas de maneio da unidade experimental, bem como uma escolha da área de produção menos susceptível à erosão, conduzirão a uma prevenção nos riscos de perda de P e na eutrofização das águas superficiais.When compared with intensive indoor production, outdoor pig production is considered by consumers as the production system that causes the least negative environmental effects and contributes to animal welfare. Nevertheless, the continuous input of nutrients in food or pig excretions, increases soil nutrients levels, as is the case with phosphorus (P. This continuous soil P

  6. A Prediction of the Damping Properties of Hindered Phenol AO-60/polyacrylate Rubber (AO-60/ACM) Composites through Molecular Dynamics Simulation

    Science.gov (United States)

    Yang, Da-Wei; Zhao, Xiu-Ying; Zhang, Geng; Li, Qiang-Guo; Wu, Si-Zhu

    2016-05-01

    Molecule dynamics (MD) simulation, a molecular-level method, was applied to predict the damping properties of AO-60/polyacrylate rubber (AO-60/ACM) composites before experimental measures were performed. MD simulation results revealed that two types of hydrogen bond, namely, type A (AO-60) -OH•••O=C- (ACM), type B (AO-60) - OH•••O=C- (AO-60) were formed. Then, the AO-60/ACM composites were fabricated and tested to verify the accuracy of the MD simulation through dynamic mechanical thermal analysis (DMTA). DMTA results showed that the introduction of AO-60 could remarkably improve the damping properties of the composites, including the increase of glass transition temperature (Tg) alongside with the loss factor (tan δ), also indicating the AO-60/ACM(98/100) had the best damping performance amongst the composites which verified by the experimental.

  7. Effects of lamellae size distributions from 40Ar/39Ar on sedimentary thermo-chronology in the San Joaquin Basin

    International Nuclear Information System (INIS)

    Jepsen, A.-M.; Lerche, I.; Thomsen, R.O.

    1990-01-01

    A model description is provided for the release of 40 Ar/ 39 Ar from detrital microclines which specifically includes the effects of grain size distributions, thus allowing smaller grains to release argon faster than the more retentive larger grains. The model also includes the effects of sedimentary thermal history after burial influencing the pre-depositional 40 Ar/ 30 Ar ratio. Application of the model to the measured age spectra from six depths in the Tejon Block and four in the Basin Block of the San Joaquin Basin demonstrates that the grain size distribution effect plays a major role in masking the extraction of thermal history information from the observed age spectra. In addition, the grain size effect is not systematic with depth, and other competing effects, such as isotopic fractionation of diffusion coefficients, multi-provenance depositional supply, and variable concentrations of 40 Ar and 39 K per microcline at burial deposition time, make the extraction of thermal history information even more difficult. (author)

  8. Timing of Secondary Hydrothermal Alteration of the Luobusa Chromitites Constrained by Ar/Ar Dating of Chrome Chlorites

    Directory of Open Access Journals (Sweden)

    Wei Guo

    2018-05-01

    Full Text Available Chrome chlorites are usually found as secondary phases formed by hydrothermal alteration of chromite deposits and associated mafic/ultramafic rocks. Here, we report the 40Ar/39Ar age of chrome chlorites separated from the Luobusa massive chromitites which have undergone secondary alteration by CO2-rich hydrothermal fluids. The dating results reveal that the intermediate heating steps (from 4 to 10 of sample L7 generate an age plateau of 29.88 ± 0.42 Ma (MSWD = 0.12, plateau 39Ar = 74.6%, and the plateau data points define a concordant inverse isochron age of 30.15 ± 1.05 Ma (MSWD = 0.08, initial 40Ar/36Ar = 295.8 ± 9.7. The Ar release pattern shows no evidence of later degassing or inherited radiogenic component indicated by an atmospheric intercept, thus representing the age of the hydrothermal activity. Based on the agreement of this hydrothermal age with the ~30 Ma adakitic plutons exposed in nearby regions (the Zedong area, tens of kilometers west Luobusa and the extensive late Oligocene plutonism distributed along the southeastern Gangdese magmatic belt, it is suggested that the hydrothermal fluids are likely related to the ~30 Ma magmatism. The hydrothermal fluid circulation could be launched either by remote plutons (such as the Sangri granodiorite, the nearest ~30 Ma pluton west Luobusa or by a similar coeval pluton in the local Luobusa area (inferred, not found or reported so far. Our results provide important clues for when the listwanites in Luobusa were formed.

  9. An 40 Ar- 39 Ar study of the Cape Verde hot spot

    DEFF Research Database (Denmark)

    Holm, Paul Martin; Grandvuinet, Tanja; Wilson, James Richard

    2008-01-01

    The 40Ar-39Ar analyses of 28 groundmass separates from volcanic rocks from the islands of Santiago, Sal, and São Vicente, Cape Verde archipelago, are presented. The new age data record the volcanic evolution for Santiago from 4.6 to 0.7 Ma, for Sal from around 15 to 1.1 Ma, and for São Vicente from...... Cretaceous age for limestones deposited on the seafloor and later uplifted. The Cape Verde Rise is indicated to have fully formed in the early Miocene around 22 Ma, accompanied by the initial alkaline volcanism. Considerable volcanism on Sal, Boa Vista, and Maio took place in the Miocene and Pliocene...

  10. Tolerância de porta-enxertos de videira ao alumínio do solo

    Directory of Open Access Journals (Sweden)

    José Carlos Fráguas

    1999-07-01

    Full Text Available Onze porta-enxertos e duas cultivares americanas de videira (Vitis spp foram avaliadas mediante níveis de saturação por Al no solo (Cambissolo Húmico álico, objetivando alcançar a tolerância diferenciada ao Al. O trabalho foi conduzido em casa de vegetação, com seis tratamentos completamente casualizados e quatro repetições, na Embrapa-Centro Nacional de Pesquisa de Uva e Vinho, em Bento Gonçalves, RS, no período de 1987 a 1990. As características avaliadas foram: altura das plantas, comprimento das raízes, peso da matéria seca da parte aérea e das raízes e teores de P, K, Ca e Mg em folhas e raízes. Diante dos acréscimos ou aumentos verificados em cada característica (variação % e por cultivar, foi possível estabelecer a tolerância diferenciada das cultivares. O teor de K na parte aérea não foi afetado pelos níveis de saturação por Al, enquanto os teores de Ca e Mg foram os mais afetados. O teor de P teve um comportamento estável entre os níveis de saturação por Al. As cultivares Isabel e Cunningham apresentaram diferença na tolerância ao Al do solo; a Cunningham teve melhor comportamento. Os porta-enxertos R99, Rupestris du Lot e Kober 5BB, juntamente com Isabel, foram os mais sensíveis ao Al, e P1103, 101-14 e 196-17Cl foram os mais tolerantes.

  11. Uma história de vida, um olhar diferente: a resiliência como um caminho aberto para a reabilitação e integração na sociedade

    OpenAIRE

    Nascimento, Rui Lourenço Viegas do

    2012-01-01

    O trabalho de investigação que ora se apresenta consiste numa dissertação de Mestra-do no domínio da Educação Social e inscreve-se no título Uma História de Vida, um Olhar Diferente - A Resiliência como um Caminho Aberto para a Reabilitação e Integração na Sociedade tendo como objetivos contribuir para a valorização e aprofundamento da temática da deficiência, através de uma História de Vida. Uma História de Vida é sempre um registo único que nos pertence enquanto seres individuais. É a pa...

  12. Marketing de Relacionamento: Agregando Valor ao Negócio com Big Data

    Directory of Open Access Journals (Sweden)

    Ana Cláudia Borges Coutrim dos Reis

    2016-12-01

    Full Text Available Nos últimos anos, as constantes inovações tecnológicas, o aumento exponencial do volume de dados, junto às evoluções nas tendências de consumo, geraram um cenário global de grandes desafios para as organizações. O uso de tecnologias de Big Data, para análise do volume crescente de dados, disponíveis no mundo virtual globalizado, oferece uma nova visão sobre o mercado e pode contribuir com o futuro das organizações, por meio da disponibilização de informações de qualidade que apoiarão fortemente a tomada de decisão. Nesse cenário de alta competitividade, considerar o contexto de análises de dados, com o uso de tecnologias de Big Data, pode ampliar a visão das empresas para as tendências do mercado, favorecendo a identificação de estratégias melhor direcionadas aos perfis de comportamentos e preferências de consumo. O objetivo da pesquisa é investigar como o uso das tecnologias de Big Data pode ampliar a capacidade do marketing de relacionamento das organizações, agregando valor ao negócio. Os resultados demonstram que as organizações que fazem uso das tecnologias de Big Data, conseguem melhor definir suas estratégias de marketing de relacionamento com os clientes, obtendo como resultados relacionamentos mais duradouros com o mercado e seus clientes e retornos favoráveis aos seus negócios. Em um futuro próximo, a utilização de Big Data, para ampliação das estratégias de marketing de relacionamento, serão regras de sobrevivência para as organizações. O diferencial estará na forma como o gestor interpretará as informações disponíveis e agirá para alcançar os resultados almejados.

  13. Electronic-state distribution of Ar* produced from Ar+(2P3/2)/2e- collisional radiative recombination in an argon flowing afterglow

    International Nuclear Information System (INIS)

    Tsuji, Masaharu; Matsuzaki, Toshinori; Tsuji, Takeshi

    2002-01-01

    The Ar + /2e - collisional radiative recombination has been studied by observing UV and visible emissions of Ar* in an Ar flowing afterglow. In order to clarify recombination mechanism, the Ar + ( 2 P 3/2 ) spin-orbit component was selected by using a filter gas of the Ar + ( 2 P 1/2 ) component. Spectral analysis indicated that 34 Ar*(4p, 4d, 5p, 5d, 6s, 6p, 6d, 4p ' , 4d ' , 5p ' , 5d ' , 6s ' ) states in the 13.08-15.33 eV range are produced. The electronic-state distribution decreased with an increase in the excitation energy of Ar*, which was expressed by a Boltzmann electronic temperature of 0.54 eV. The formation ratios of the 4p: 4d + 5p + 5d + 6s + 6p + 6d: 4p ' : 4d ' + 5p ' + 5d ' + 6s ' states were 43%, 2.8%, 54%, and 0.31%, respectively. The high formation ratio of the 4p ' state having an Ar + ( 2 P 1/2 ) ion core in the Ar + ( 2 P 3/2 )/2e - recombination indicated that such a two-electron process as an electron transfer to an inner 3p orbital followed by excitation of a 3p electron to an outer 4p orbital occurs significantly. The higher formation ratios of 4d + 5p + 5d + 6s + 6p + 6d than those of 4d ' + 5p ' + 5d ' + 6s ' led us to conclude the formation of these upper states dominantly proceeds through one electron transfer to an outer nl orbital of Ar + ( 2 P 3/2 )

  14. Characterization of a novel androgen receptor (AR) coregulator RIPK1 and related chemicals that suppress AR-mediated prostate cancer growth via peptide and chemical screening.

    Science.gov (United States)

    Hsu, Cheng-Lung; Liu, Jai-Shin; Lin, Ting-Wei; Chang, Ying-Hsu; Kuo, Yung-Chia; Lin, An-Chi; Ting, Huei-Ju; Pang, See-Tong; Lee, Li-Yu; Ma, Wen-Lung; Lin, Chun-Cheng; Wu, Wen-Guey

    2017-09-19

    Using bicalutamide-androgen receptor (AR) DNA binding domain-ligand binding domain as bait, we observed enrichment of FxxFY motif-containing peptides. Protein database searches revealed the presence of receptor-interacting protein kinase 1 (RIPK1) harboring one FxxFY motif. RIPK1 interacted directly with AR and suppressed AR transactivation in a dose-dependent manner. Domain mapping experiments showed that the FxxFY motif in RIPK1 is critical for interactions with AR and the death domain of RIPK1 plays a crucial role in its inhibitory effect on transactivation. In terms of tissue expression, RIPK1 levels were markedly higher in benign prostate hyperplasia and non-cancerous tissue regions relative to the tumor area. With the aid of computer modeling for screening of chemicals targeting activation function 2 (AF-2) of AR, we identified oxadiazole derivatives as good candidates and subsequently generated a small library of these compounds. A number of candidates could effectively suppress AR transactivation and AR-related functions in vitro and in vivo with tolerable toxicity via inhibiting AR-peptide, AR-coregulator and AR N-C interactions. Combination of these chemicals with antiandrogen had an additive suppressive effect on AR transcriptional activity. Our collective findings may pave the way in creating new strategies for the development and design of anti-AR drugs.

  15. The development of AR book for computer learning

    Science.gov (United States)

    Phadung, Muneeroh; Wani, Najela; Tongmnee, Nur-aiynee

    2017-08-01

    Educators need to provide the alternative educational tools to foster learning outcomes of students. By using AR technology to create exciting edutainment experiences, this paper presents how augmented reality (AR) can be applied in the education. This study aims to develop the AR book for tenth grade students (age 15-16) and evaluate its quality. The AR book was developed based on ADDIE framework processes to provide computer learning on software computer knowledge. The content was accorded with the current Thai education curriculum. The AR book had 10 pages in three topics (the first was "Introduction," the second was "System Software" and the third was "Application Software"). Each page contained markers that placed virtual objects (2D animation and video clip). The obtained data were analyzed in terms of average and standard deviation. The validity of multimedia design of the AR book was assessed by three experts in multimedia design. A five-point Likert scale was used and the values were X¯ =4 .84 , S.D. = 1.27 which referred to very high. Moreover, three content experts, who specialize in computer teaching, evaluated the AR book's validity. The values determined by the experts were X¯ =4 .69 , S.D. = 0.29 which referred to very high. Implications for future study and education are discussed.

  16. Glycogen synthase kinase-3 inhibitors suppress the AR-V7-mediated transcription and selectively inhibit cell growth in AR-V7-positive prostate cancer cells.

    Science.gov (United States)

    Nakata, Daisuke; Koyama, Ryokichi; Nakayama, Kazuhide; Kitazawa, Satoshi; Watanabe, Tatsuya; Hara, Takahito

    2017-06-01

    Recent evidence suggests that androgen receptor (AR) splice variants, including AR-V7, play a pivotal role in resistance to androgen blockade in prostate cancer treatment. The development of new therapeutic agents that can suppress the transcriptional activities of AR splice variants has been anticipated as the next generation treatment of castration-resistant prostate cancer. High-throughput screening of AR-V7 signaling inhibitors was performed using an AR-V7 reporter system. The effects of a glycogen synthase kinase-3 (GSK3) inhibitor, LY-2090314, on endogenous AR-V7 signaling were evaluated in an AR-V7-positive cell line, JDCaP-hr, by quantitative reverse transcription polymerase chain reaction. The relationship between AR-V7 signaling and β-catenin signaling was assessed using RNA interference. The effect of LY-2090314 on cell growth in various prostate cancer cell lines was also evaluated. We identified GSK3 inhibitors as transcriptional suppressors of AR-V7 using a high-throughput screen with an AR-V7 reporter system. LY-2090314 suppressed the reporter activity and endogenous AR-V7 activity in JDCaP-hr cells. Because silencing of β-catenin partly rescued the suppression, it was evident that the suppression was mediated, at least partially, via the activation of β-catenin signaling. AR-V7 signaling and β-catenin signaling reciprocally regulate each other in JDCaP-hr cells, and therefore, GSK3 inhibition can repress AR-V7 transcriptional activity by accumulating intracellular β-catenin. Notably, LY-2090314 selectively inhibited the growth of AR-V7-positive prostate cancer cells in vitro. Our findings demonstrate the potential of GSK3 inhibitors in treating advanced prostate cancer driven by AR splice variants. In vivo evaluation of AR splice variant-positive prostate cancer models will help illustrate the overall significance of GSK3 inhibitors in treating prostate cancer. © 2017 Wiley Periodicals, Inc.

  17. ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer.

    Science.gov (United States)

    Lev, Avital; Lulla, Amriti R; Ross, Brian C; Ralff, Marie D; Makhov, Petr B; Dicker, David T; El-Deiry, Wafik S

    2018-05-01

    Androgen receptor (AR) signaling plays a key role in prostate cancer progression, and androgen deprivation therapy (ADT) is a mainstay clinical treatment regimen for patients with advanced disease. Unfortunately, most prostate cancers eventually become androgen-independent and resistant to ADT with patients progressing to metastatic castration-resistant prostate cancer (mCRPC). Constitutively activated AR variants (AR-V) have emerged as mediators of resistance to AR-targeted therapy and the progression of mCRPC, and they represent an important therapeutic target. Out of at least 15 AR-Vs described thus far, AR-V7 is the most abundant, and its expression correlates with ADT resistance. ONC201/TIC10 is the founding member of the imipridone class of small molecules and has shown anticancer activity in a broad range of tumor types. ONC201 is currently being tested in phase I/II clinical trials for advanced solid tumors, including mCRPC, and hematologic malignancies. There has been promising activity observed in patients in early clinical testing. This study demonstrates preclinical single-agent efficacy of ONC201 using in vitro and in vivo models of prostate cancer. ONC201 has potent antiproliferative and proapoptotic effects in both castration-resistant and -sensitive prostate cancer cells. Furthermore, the data demonstrate that ONC201 downregulates the expression of key drivers of prostate cancer such as AR-V7 and downstream target genes including the clinically used biomarker PSA (KLK3). Finally, the data also provide a preclinical rationale for combination of ONC201 with approved therapeutics for prostate cancer such as enzalutamide, everolimus (mTOR inhibitor), or docetaxel. Implications: The preclinical efficacy of ONC201 as a single agent or in combination, in hormone-sensitive or castration-resistant prostate cancer, suggests the potential for immediate clinical translation. Mol Cancer Res; 16(5); 754-66. ©2018 AACR . ©2018 American Association for Cancer

  18. AR-Signaling in Human Malignancies: Prostate Cancer and Beyond

    Directory of Open Access Journals (Sweden)

    Michael T. Schweizer

    2017-01-01

    Full Text Available In the 1940s Charles Huggins reported remarkable palliative benefits following surgical castration in men with advanced prostate cancer, and since then the androgen receptor (AR has remained the main therapeutic target in this disease. Over the past couple of decades, our understanding of AR-signaling biology has dramatically improved, and it has become apparent that the AR can modulate a number of other well-described oncogenic signaling pathways. Not surprisingly, mounting preclinical and epidemiologic data now supports a role for AR-signaling in promoting the growth and progression of several cancers other than prostate, and early phase clinical trials have documented preliminary signs of efficacy when AR-signaling inhibitors are used in several of these malignancies. In this article, we provide an overview of the evidence supporting the use of AR-directed therapies in prostate as well as other cancers, with an emphasis on the rationale for targeting AR-signaling across tumor types.

  19. AR Signaling in Human Malignancies: Prostate Cancer and Beyond.

    Science.gov (United States)

    Antonarakis, Emmanuel S

    2018-01-18

    The notion that androgens and androgen receptor (AR) signaling are the hallmarks of prostate cancer oncogenesis and disease progression is generally well accepted. What is more poorly understood is the role of AR signaling in other human malignancies. This special issue of Cancers initially reviews the role of AR in advanced prostate cancer, and then explores the potential importance of AR signaling in other epithelial malignancies. The first few articles focus on the use of novel AR-targeting therapies in castration-resistant prostate cancer and the mechanisms of resistance to novel antiandrogens, and they also outline the interaction between AR and other cellular pathways, including PI3 kinase signaling, transcriptional regulation, angiogenesis, stromal factors, Wnt signaling, and epigenetic regulation in prostate cancer. The next several articles review the possible role of androgens and AR signaling in breast cancer, bladder cancer, salivary gland cancer, and hepatocellular carcinoma, as well as the potential treatment implications of using antiandrogen therapies in these non-prostatic malignancies.

  20. Grau de exposição a praguicidas organoclorados em moradores de aterro a céu aberto Levels of exposure to organochlorine pesticides in open-air dump dwellers

    Directory of Open Access Journals (Sweden)

    Eladio Santos Filho

    2003-08-01

    Full Text Available OBJETIVO: Estimar o grau de exposição interna aos praguicidas organoclorados (POP dos moradores de um atêrro a céu aberto. MÉTODOS: Estudo observacional, de aferição simultânea e controlado, cujo fator de estudo foi residir em área contaminada por POP e o efeito foi a concentração sanguínea dessas substâncias. A população de estudo foi de 238 pessoas residentes em um aterro a céu aberto (Pilões, no município de Cubatão, SP; e a população de controle ficou dimensionada em 258 pessoas, também residentes no mesmo município (Cota 200. Foram analisados os praguicidas HCB, p-p'DDT, p-p'DDE, p-p'DDD, o-p'DDT, a HCH; b HCH; g HCH; Aldrin; Dieldrin; Endrin; Heptaclor; Heptaclor-epoxi e Mirex. RESULTADOS: Os teores médios sangüíneos de HCB em Pilões foram de 4,66 µg/L, 155 vezes maior que a média na Cota 200 (0,03 µg/L. Em Pilões, os teores médios de DDT total foram de 3,71 µg/L, duas vezes maior do que na Cota 200 (1,85 µg/L e o HCH total apresentou concentrações sangüíneas seis vezes maiores em Pilões, 0,84 µg/L, contra 0,13 µg/L. CONCLUSÕES: Evidenciou-se associação positiva entre residir em Pilões e apresentar teores sangüíneos de POP, com risco muitas vezes maior quando comparado a localidades sem a presença desses contaminantes.OBJECTIVE: To estimate the degree of internal exposure to organochlorine pesticides (persistent organic pollutants, POP among inhabitants of an open-air dump. METHODS: This was an observational study with simultaneous measurement and control, in which the criterion for subjects was that they dwelled in an area contaminated by POP and the effect of such contamination was the concentration of such substances into the blood. The study population consisted of 238 people living on an open-air dump in Pilões, in the municipality of Cubatão, SP, Brazil, and the control population was formed by 258 people, also resident in that municipality, in the Cota 200 district. The following

  1. Fusion-fission in Ar-heavy nuclei collisions

    International Nuclear Information System (INIS)

    Zaric, Alexandre

    1984-01-01

    Fusion-fission products have been studied for three reactions: Ar + Au, Ar + Bi and Ar + U (5.25-7.5 MeV/u). By measuring symmetric fragmentation components (fission-like events), cross sections for fusion were deduced and compared with the prediction of static and dynamic models. With increasing projectile energy, the width of the mass distributions strongly increases for the two lighter systems. By contrast, for Ar + U it remains essentially constant at a very large value. These results clearly demonstrate that the large increase of the width of the mass distribution cannot be attributed simply to large values of the angular momentum. However, they can be explained by the occurrence of a different dissipative process, fast fission, which can be expected if there is no barrier to fission. For the reaction Ar + Au, the total kinetic-energy distributions were also studied in detail. In this case fast fission occurs only at high incident energy. The average total kinetic energy (TKE) was found to be constant with increasing energy. (author) [fr

  2. Electron temperatures of inductively coupled Cl2-Ar plasmas

    International Nuclear Information System (INIS)

    Fuller, N.C.M.; Donnelly, Vincent M.; Herman, Irving P.

    2002-01-01

    Trace rare gases optical emission spectroscopy has been used to measure the electron temperature, T e , in a high-density inductively coupled Cl 2 -Ar plasma at 18 mTorr as function of the 13.56 MHz radio frequency power and Ar fraction. Only the Kr and Xe emission lines were used to determine T e , because of evidence of radiation trapping when the Ar emission lines were also used for larger Ar fractions. At 600 W (10.6 W cm-2), T e increases from ∼4.0±0.5 eV to ∼6.0±2.0 eV as the Ar fraction increases from 1% to 96%. In the H (inductive, bright) mode, T e , for a 'neat' chlorine plasma (including 1% of each He/Ne/Ar/Kr/Xe) increases only slightly from ∼3.8 to 4.0 eV as power increases from 450 to 750 W. This increase is much larger for larger Ar fractions, such as from ∼4.0 to 7.3 eV for 78% Ar. Most of these effects can be understood using the fundamental particle balance equation

  3. Ars Electronica

    DEFF Research Database (Denmark)

    Kristensen, Thomas Bjørnsten

    2009-01-01

    Anmeldelse af Ars Electronica festivalen 3. - 8. september, 2009 i Linz, Østrig, der fejrede 30 års jubilæum under temaet "Human Nature". Festivalen fokuserer på interaktion mellem menneske, teknologi, kunst og samfund med særlig vægt på udviklingen af computeren og det digitale. Udgivelsesdato: 15.12...

  4. Heterogeneous 40Ar/39Ar laser probe apparent ages in low-grade mylonitic rocks: Constraining a meaningful geological age

    International Nuclear Information System (INIS)

    Arancibia, G

    2001-01-01

    Obtaining meaningful geological ages from mylonitic rocks has been a major problem for structural geologist, because apparent ages have usually no geologic significance. Over the last years, in situ high spatial resolutions 40 Ar/ 39 Ar studies (e.g. Ruffet et al., 1991; Reddy et al., 1996; Pickles et al., 1997), permit obtain apparent ages of mineral and link them directly with textural, microstructural and chemical patterns that can previously be obtained by optical and scanning electron (SEM) microscopes and electron microprobe. In this work, heterogeneous 40 Ar/ 39 Ar laser probe ages from low-grade volcanic mylonites show complex argon distributions patterns. Inverse isochron analysis suggests that most obtained apparent ages contain argon excess and only younger ages have a meaningful geologically interpretation (au)

  5. A composite microdose Adaptive Response (AR) and Bystander Effect (BE) model-application to low LET and high LET AR and BE data.

    Science.gov (United States)

    Leonard, Bobby E

    2008-08-01

    It has been suggested that Adaptive Response (AR) may reduce risk of adverse health effects due to ionizing radiation. But very low dose Bystander Effects (BE) may impose dominant deleterious human risks. These conflicting behaviors have stimulated controversy regarding the Linear No-Threshold human risk model. A dose and dose rate-dependent microdose model, to examine AR behavior, was developed in prior work. In the prior work a number of in vitro and in vivo dose response data were examined with the model. Recent new data show AR behavior with some evidence of very low dose BE. The purpose of this work is to supplement the microdose model to encompass the Brenner and colleagues BaD (Bystander and Direct Damage) model and apply this composite model to obtain new knowledge regarding AR and BE and illustrate the use of the model to plan radio-biology experiments. The biophysical composite AR and BE Microdose Model quantifies the accumulation of hits (Poisson distributed, microdose specific energy depositions) to cell nucleus volumes. This new composite AR and BE model provides predictions of dose response at very low dose BE levels, higher dose AR levels and even higher dose Direct (linear-quadratic) Damage radiation levels. We find good fits of the model to both BE data from the Columbia University microbeam facility and combined AR and BE data for low Linear Energy Transfer (LET) and high LET data. A Bystander Factor of about 27,000 and an AR protection factor of 0.61 are obtained for the low LET in vivo mouse spleen exposures. A Bystander Factor of 317 and an AR protection factor of 0.53 are obtained for high LET radon alpha particles in human lymphocytes. In both cases the AR is activated at most by one or two radiation induced charged particle traversals through the cell nucleus. The results of the model analysis is consistent with a premise that both Bystander damage and Adaptive Response radioprotection can occur in the same cell type, derived from the same

  6. 40Ar/39Ar geochronology of the El Teniente porphyry copper deposit

    International Nuclear Information System (INIS)

    Maksaev, V; Munizaga, F; McWilliams, M; Thiele, K; Arevalo, A; Zuniga, P; Floody, R

    2001-01-01

    breccias. Phyllic alteration primarily occurs as quartz-sericite haloes of quartz-sulfide-sulfate veinlets within the perimeter of the orebody, and slightly overprints potassic alteration. Propylitic alteration occurs largely peripheral to ore-grade rock. The relatively restricted development of phyllic alteration and the occurrence of the central breccia conflict with the classic porphyry copper model of Lowell and Gilbert (1970), but El Teniente may be regarded as a 'variation on a theme' of the classic model, as suggested by Gustafson and Hunt (1975). The exceedingly large size of the El Teniente deposit, coupled with its apparently young mineralization age prompted us to initiate a systematic 40 Ar/ 39 Ar study whose goals are to determine the age(s) of the hydrothermal event(s) that produced such a remarkable copper concentration and ultimately to estimate the duration of the hydrothermal activity at El Teniente. This is particularly relevant to an understanding of the processes that formed super-giant high-grade copper deposits in the Chilean Andes and elsewhere. We report here 32 total fusion 40 Ar/ 39 Ar ages from sericite and biotite from different lithologic units of El Teniente and five step-heating 40 Ar- 39 Ar ages of samples previously dated using conventional K-Ar methods (Cuadra, 1986) (au)

  7. The ChArMEx database

    Science.gov (United States)

    Ferré, Hélène; Belmahfoud, Nizar; Boichard, Jean-Luc; Brissebrat, Guillaume; Cloché, Sophie; Descloitres, Jacques; Fleury, Laurence; Focsa, Loredana; Henriot, Nicolas; Mière, Arnaud; Ramage, Karim; Vermeulen, Anne; Boulanger, Damien

    2015-04-01

    The Chemistry-Aerosol Mediterranean Experiment (ChArMEx, http://charmex.lsce.ipsl.fr/) aims at a scientific assessment of the present and future state of the atmospheric environment in the Mediterranean Basin, and of its impacts on the regional climate, air quality, and marine biogeochemistry. The project includes long term monitoring of environmental parameters , intensive field campaigns, use of satellite data and modelling studies. Therefore ChARMEx scientists produce and need to access a wide diversity of data. In this context, the objective of the database task is to organize data management, distribution system and services, such as facilitating the exchange of information and stimulating the collaboration between researchers within the ChArMEx community, and beyond. The database relies on a strong collaboration between ICARE, IPSL and OMP data centers and has been set up in the framework of the Mediterranean Integrated Studies at Regional And Locals Scales (MISTRALS) program data portal. ChArMEx data, either produced or used by the project, are documented and accessible through the database website: http://mistrals.sedoo.fr/ChArMEx. The website offers the usual but user-friendly functionalities: data catalog, user registration procedure, search tool to select and access data... The metadata (data description) are standardized, and comply with international standards (ISO 19115-19139; INSPIRE European Directive; Global Change Master Directory Thesaurus). A Digital Object Identifier (DOI) assignement procedure allows to automatically register the datasets, in order to make them easier to access, cite, reuse and verify. At present, the ChArMEx database contains about 120 datasets, including more than 80 in situ datasets (2012, 2013 and 2014 summer campaigns, background monitoring station of Ersa...), 25 model output sets (dust model intercomparison, MEDCORDEX scenarios...), a high resolution emission inventory over the Mediterranean... Many in situ datasets

  8. Multibeam investigation of an artificial reef settlement in the Adriatic sea (Italy 33 years after its deployment

    Directory of Open Access Journals (Sweden)

    Sarine Manoukian

    2011-01-01

    Full Text Available Artificial reefs (ARs are becoming a popular biological and management component in shallow water environments characterized by soft seabed, representing both important marine habitats and tools to manage coastal fisheries and resources. Because of the unstable nature of sediments, they require a detailed and systematic investigation that acoustic systems can provide. An AR into the marine environment acts as an open system with exchange of material and energy, altering the physical and biological characteristics of the surrounding area. The AR stability will depend on the balance of scour, settlement, and burial resulting from ocean conditions over time. The acoustic systems are efficient tools in monitoring the environmental evolution around ARs, whereas water turbidity can limit visual dive and ROV inspections. High-frequency multibeam echosounder offers the potential of detecting fine-scale distribution of reef units, providing an unprecedented level of resolution, coverage, and spatial definition. In 2008 the EM3002 multibeam was used to investigate the first scientifically-planned AR in Italy deployed during 1974-75. After 33 years the AR is almost in perfect condition. A considerable scouring around the structures and some vertical/horizontal movements of the single units have occurred. Moreover a deepening of the whole area hosting the AR was observed.Os recifes artificiais (ARs estão se tornando um componente biológico e de manejo de ambientes de áreas rasas com substratos característicos não rígidos, representando habitats marinhos importantes e ainda constituindo uma ferramenta para o manejo da pesca e dos recursos costeiros. Devido à natureza instável dos sedimentos, exigem um estudo detalhado e sistemático que os sistemas acústicos podem disponibilizar. Um RA atua no ambiente marinho como um sistema aberto com troca de materiais e energia, alterando as características físicas e biológicas das áreas que o cerca. A

  9. 40Ar/39Ar dating and geochemistry of tholeiitic magmatism related to the early opening of the Central Atlantic rift

    International Nuclear Information System (INIS)

    Sebai, A.; Feraud, G.; Bertrand, H.; Hanes, J.

    1991-01-01

    Tholeiitic effusive and intrusive magnetism from Iberia, Morocco, Algeria and Mali, realted to the early opening of the Central Atlantic rift, was dated by the 40 Ar/ 39 Ar step-heating method. Four plateau ags, rangin from 203.7±2.7 to 197.1±1.8 Ma, were obtained on plagioclase from dykes from theTaoudenni area (Mali) and two lava flows from Morocco. The Messejana dyke (Iberia), which previously yielded discrepant conventional K-Ar dates, did not furnish any 40 Ar/ 39 Ar plateau dates. However, there is a clear inverse relationship between apparent age and K/Ca atio for gas fractions from a plagioclase separate (proportional to the alteration degree) which, combined with dates obtained on amphibole, biotite and pyroxene, allows us to determine an age of around 200 Ma for this body. These data, and those obtained on the Foum Zguid (Morocco) and the Ksi Ksou (Algeria) dykes, give evidence of a brief magmatic event (between 206 and 195 Ma ago) which affected a large area ca. 2500 km long. Trace-element modelling shows that most of these formations originated from a homogeneous, enriched, source material. Such a brief magmatic episode related to the opening of a continental rift is in agreement with findings in other magmatic provinces (e.g. the Deccan traps and the Red Sea rift, precisely dated by the 40 Ar/ 39 Ar method as well). (orig.)

  10. ARABIC LIGHT STEMMER (ARS

    Directory of Open Access Journals (Sweden)

    ASMA AL-OMARI

    2014-12-01

    Full Text Available Stemming is a main step used to process textual data. It is usually used in several types of applications such as: text mining, information retrieval (IR, and natural language processing (NLP. A major task in stemming is to standardize words; which can be achieved by reducing each word to its base (root or stem. Arabic stemming is not an easy task. Unlike other languages, Arabic language is a highly inflected language, since it uses many inflectional forms. Researchers are divided on the benefit of using stemming in fields of IR, NLP...etc., since in Arabic the morphological variants of a certain word are not always semantically related. The aim of this paper is to design and implement a new Arabic light stemmer (ARS which is not based on Arabic root patterns. Instead, it depends on well defined mathematical rules and several relations between letters. A series of tests were conducted on ARS stemmer to compare its effectiveness with the effectiveness of two other Arabic stemmers. Test shows clearly the effectiveness superiority of ARS compared to effectiveness of these two Arabic stemmers.

  11. Precipitação efetiva e interceptação da chuva em um fragmento florestal com diferentes estágios de regeneração

    Directory of Open Access Journals (Sweden)

    Alexandre Simões Lorenzon

    2013-08-01

    Full Text Available Este trabalho teve por objetivo avaliar a precipitação efetiva e a interceptação da chuva em um fragmento de Floresta Estacional Semidecidual em estágio inicial e avançado de regeneração no Município de Viçosa, Minas Gerais, no período de agosto de 2009 a fevereiro de 2011. Foram demarcadas seis parcelas, três na área de regeneração inicial e três na área de regeneração avançada. Para quantificar a precipitação interna e o escoamento pelo tronco, foram instalados 25 pluviômetros em cada parcela e coletores nas árvores com circunferência 15 cm. Além disso, um pluviômetro foi instalado em local aberto para quantificar a precipitação em aberto, que no período estudado foi igual a 1.509,96 mm. Em média, 85,08 e 74,93% da precipitação em aberto, respectivamente, no estágio inicial e avançado de regeneração, chegam ao solo via precipitação efetiva. A interceptação pelo dossel florestal foi maior na área avançada do que na área inicial de regeneração, correspondendo, respectivamente, a 25,07 e 14,92% da precipitação em aberto, o que sugere que áreas mais densamente povoadas interceptam maior quantidade de chuva e, consequentemente, geram menor precipitação efetiva.

  12. Novos meridianos da produção editorial em castelhano: o papel de espanhóis exilados pela Guerra Civil na Argentina e no México New axes of editorial production in Castilian: the role of Spanish civil war exiles in Argentina and Mexico

    Directory of Open Access Journals (Sweden)

    Gabriela Pellegrino Soares

    2007-12-01

    Full Text Available Este artigo tem por objetivo lançar luz sobre o impacto da Guerra Civil Espanhola sobre a indústria editorial argentina e mexicana. Em particular, pretende enfocar as contribuições oferecidas por refugiados ou exilados espanhóis que, uma vez estabelecidos na outra margem do Atlântico, procuraram retomar seus ofícios de origem, inserindo-se nas gráficas e editoras existentes nesses dois países ou fundando novos negócios livreiros. Tanto o México como, em especial, a Argentina, beneficiaram-se da crise impingida pela guerra à indústria editorial da antiga metrópole para explorar o vasto mercado aberto aos impressos em língua espanhola.This article aims at shedding light on the impact of the Spanish Civil War on the publishing industry in Argentina and in Mexico. Particularly, it intends to analyze the contributions of Spanish refugees or in exile who, once established on the other border of the Atlantic Ocean, tried to go back to their previous jobs, working at preexisting publishing houses in those two countries or creating new ones. Both Mexico and specially Argentina took advantage of the Spanish publishing industry's crises so to explore the vast business opportunities for books in Spanish.

  13. 40Ar/39Ar Dating of Zn-Pb-Ag Mineralization in the Northern Brooks Range, Alaska

    Science.gov (United States)

    Werdon, Melanie B.; Layer, Paul W.; Newberry, Rainer J.

    2004-01-01

    The 40Ar/39Ar laser step-heating method potentially can be used to provide absolute ages for a number of formerly undatable, low-temperature ore deposits. This study demonstrates the use of this method by determining absolute ages for Zn-Pb-Ag sediment-hosted massive sulfide deposits and vein-breccia occurrences found throughout a 300-km-long, east-west-trending belt in the northern Brooks Range, Alaska. Massive sulfide deposits are hosted by Mississippian to Pennsylvanian(?) black carbonaceous shale, siliceous mudstone, and lesser chert and carbonate turbidites of the Kuna Formation (e.g., Red Dog, Anarraaq, Lik (Su), and Drenchwater). The vein-breccia occurrences (e.g., Husky, Story Creek, West Kivliktort Mountain, Vidlee, and Kady) are hosted by a deformed but only weakly metamorphosed package of Upper Devonian to Lower Mississippian mixed continental and marine clastic rocks (the Endicott Group) that stratigraphically underlie the Kuna Formation. The vein-breccias are mineralogically similar to, but not spatially associated with, known massive sulfide deposits. The region's largest shale-hosted massive sulfide deposit is Red Dog; it has reserves of 148 Mt grading 16.6 percent zinc, 4.5 percent lead, and 77 g of silver per tonne. Hydrothermally produced white mica in a whole-rock sample from a sulfide-bearing igneous sill within the Red Dog deposit yielded a plateau age of 314.5 Ma. The plateau age of this whole-rock sample records the time at which temperatures cooled below the argon closure temperature of the white mica and is interpreted to represent the minimum age limit for massive sulfide-related hydrothermal activity in the Red Dog deposit. Sulfide-bearing quartz veins at Drenchwater crosscut a hypabyssal intrusion with a maximum biotite age of 337.0 Ma. Despite relatively low sulfide deposition temperatures in the vein-breccia occurrences (162°-251°C), detrital white mica in sandstone immediately adjacent to large vein-breccia zones was partially to

  14. Criação intensiva de suínos em confinamento ou ao ar livre: estudo meta-analítico do desempenho zootécnico nas fases de crescimento e terminação e avaliação de carcaça e carne no Longissimus dorsi Intensive pig production in confinement or outdoor systems: a meta-analytical study of the production performance in the growing and finishing phases and carcass and meat evaluation from the Longissimus dorsi

    Directory of Open Access Journals (Sweden)

    Alice Bogoni Demori

    2012-07-01

    Full Text Available Uma meta-análise foi realizada para avaliar o desempenho e a qualidade de carcaça e carne de suínos em função do sistema de alojamento nas fases de crescimento/terminação. Foram selecionadas publicações indexadas com resultados de experimentos comparando variáveis de desempenho e de pós-abate de suínos alojados em sistemas intensivos convencionais ou ao ar livre. A base de dados contemplou 27 artigos publicados entre 1997 e 2009. Ao total, foram considerados 2.985 animais e 701 médias na análise de dados. A meta-análise foi realizada através de duas análises sequenciais: gráfica e de variância-covariância. O sistema de criação de suínos ao ar livre aumentou em 9% (P0,05 pelo sistema de alojamento dos suínos. Concluiu-se que o sistema de criação influencia no desempenho dos suínos, mas não interfere nas características de carcaça e carne estudadas.A meta-analysis was carried out to study performance and characteristics of carcass and meat in pigs in function of housing system during the growing/finishing period. Indexed publications with results of experiments comparing performance and post-slaughter variables of pigs housed in outdoor or conventional intensive systems were selected. In total, 2.985 animals and 701 averages were considered in the data analysis. Meta-analysis followed two sequential analyses: graphic and variance. The outdoor productive system increased in 9% (P0.05 by the housing system. It is concluded that the housing system influences the pig performance, but does not interfere in characteristics of carcass and meat.

  15. K-Ar and Ar-Ar dating of the Palaeozoic metamorphic complex from the Mid-Bosnian Schist Mts., Central Dinarides, Bosnia and Hercegovina

    International Nuclear Information System (INIS)

    Pamic, J.; Balogh, K.; Hrvatovic, H.; Balen, D.; Palinkas, L.; Jurkovic, I.

    2004-01-01

    K-Ar and Ar-Ar whole rock and mineral ages are presented for 25 samples of metamorphic rocks from the Mid-Bosnian Schist Mts., representing one of the largest allochthonous Palaeozoic terranes incorporated within the Internal Dinarides. Four main age groups can be distinguished: 1) Variscan (∼ 343 Ma), 2) post-Variscan (288-238 Ma), 3) Early Cretaceous (mainly 121-92 Ma), and 4) Eocene (59--35 Ma) ages. Apart from this, an Oligocene (31 Ma) age was obtained on Alpine vein hyalophane. The radiometric dating indicates a polyphase metamorphic evolution of the Palaeozoic formations and suggests a pre-Carboniferous age of the volcano-sedimentary protoliths, an Early Carboniferous age of Variscan metamorphism and deformation, post-Variscan volcanism, an Early Cretaceous metamorphic overprint related to out-of-sequence thrusting of the Palaeozoic complex, and an Eocene and Oligocene metamorphic overprint related to the main Alpine compressional deformation and subsequent strike-slip faulting, and uplift of the metamorphic core. Accordingly, the Mid-Bosnian Schist Mts. can be correlated in its multistage geodynamic evolution with some Palaeozoic tectonostratigraphic units from the Austroalpine domain in the Eastern Alps. (author)

  16. I-Xe and 40Ar-39Ar dating of silicate from Weekeroo Station and Netschaevo IIE iron meteorites

    International Nuclear Information System (INIS)

    Niemeyer, S.

    1980-01-01

    Silicate inclusions from two IIE iron meteorites were dated by the I-Xe and 40 Ar- 39 Ar techniques. Weekeroo Station, a 'normal' IIE iron, shows no loss of radiogenic 40 Ar at low temperature, and the well defined 40 Ar- 39 Ar plateau yields an age of 4.54 +- 0.03 Byr. The xenon data define a good I-Xe correlation with an age of + 10.9 +- 0.5 Myr relative to Bjurbole. Despite its relatively young age, Weekeroo Station's ( 129 Xe/ 132 Xe)sub(trapped) ratio (= 0.84 +- 0.05) lies significantly below the solar value. Netschaevo silicate has a chondritic composition, unlike 'normal' IIE silicate which is more differentiated. Nevertheless Netschaevo gives a 40 Ar- 39 Ar plateau-age of only 3.79 +- 0.03 Byr, with the xenon data failing to define an I-Xe isochron. Only irons from the IAB and IIE groups contain silicate inclusions, but these two groups differ in many other respects, mostly suggesting that IAB meteorites are more primitive. The I-Xe chronology supports this suggestion inasmuch as Weekeroo Station formed well after IAB silicates. The four silicate-bearing IIE irons which have now been dated can be subdivided into distinct pairs: Weekeroo Station and Colomera formed near the beginning of the solar system, while Netschaevo and Kodaikanal both formed only 3.8 Byr ago. A review of other properties of these meteorites generally supports this subdivision. This work underscores the complexity of the history of IIE meteorites; in particular, an adequate model must account for the formation of two IIE irons at 3.8 Byr without disturbing rare gases in Weekeroo Station. All formation models are quite speculative, but the one which seems best to fit the available evidence postulates two parent bodies: the 3.8 Byr old silicate formed on one parent body, all other IIE material resided in a separate body, and subsequent collision(s) mixed the young silicate with IIE metal. (author)

  17. 40Ar/ 39Ar, K-Ar and 230Th- 238U dating of the Laschamp excursion: A radioisotopic tie-point for ice core and climate chronologies

    Science.gov (United States)

    Singer, Brad S.; Guillou, Hervé; Jicha, Brian R.; Laj, Carlo; Kissel, Catherine; Beard, Brian L.; Johnson, Clark M.

    2009-08-01

    A brief period of enhanced 10Be flux that straddles the interstadial warm period known as Dansgaard-Oeschger event 10 in Greenland and its counterpart in Antarctica, the Antarctic Isotope Maximum 10 is but one consequence of the weakening of Earth's magnetic field associated with the Laschamp excursion. This 10Be peak measured in the GRIP ice core is dated at 41,250 y b2k (= before year 2000 AD) in the most recent GICC05 age model obtained from the NorthGRIP core via multi-parameter counting of annual layers. Uncertainty in the age of the 10Be peak is, however, no better than ± 1630 y at the 95% confidence level, reflecting accumulated error in identifying annual layers. The age of the Laschamp excursion [Guillou, H., Singer, B.S., Laj, C., Kissel, C., Scaillet, S., Jicha, B., 2004. On the age of the Laschamp geomagnetic excursion. Earth Planet. Sci. Lett. 227, 331-343.] is revised on the basis of new 40Ar/ 39Ar, unspiked K-Ar and 238U- 230Th data from three lava flows in the Massif Central, France, together with the 40Ar/ 39Ar age of a transitionally magnetized lava flow at Auckland, New Zealand. Combined, these data yield an age of 40,700 ± 950 y b2k, where the uncertainty includes both analytical and systematic ( 40K and 230Th decay constant) errors. Taking the radioisotopic age as a calibration tie point suggests that the layer-counting chronologies for the NorthGRIP and GISP2 ice cores are more accurate and precise than previously thought at depths corresponding to the Laschamp excursion.

  18. Quando a Escritura devém palavra

    OpenAIRE

    Cardita, Ângelo

    2009-01-01

    O estudo que se segue é uma primeira tentativa de traçar um caminho, em grande parte já aberto como veremos, passando pela «teologia litúrgica». O objectivo não é tanto demonstrar que na liturgia, na passagem do texto à voz, a escritura devém palavra e mais profundamente palavra de Deus, mas arguir a pertinência de uma tal hipótese, como forma de inter-relacionar teologia bíblica e teologia litúrgica, numa teologia da palavra.

  19. Measurements of the 40Ar(n, γ)41Ar radiative-capture cross section between 0.4 and 14.8 MeV

    Science.gov (United States)

    Bhike, Megha; Fallin, B.; Tornow, W.

    2014-09-01

    The 40Ar(n, γ)41Ar neutron capture cross section has been measured between 0.4 and 14.8 MeV neutron energy using the activation technique. The data are important for estimating backgrounds in argon-based neutrino and dark-matter detectors and in the neutrino-less double-beta decay search GERDA, which uses liquid argon as cooling and shielding medium. For the first time the 40Ar(n, γ)41Ar cross section has been measured for neutron energies above 1 MeV. Our results are compared to the evaluation ENDF/B-VII.1 and the calculated prediction TENDL-2013. The latter agrees very well with the present results.

  20. Spatial autocorrelation method using AR model; Kukan jiko sokanho eno AR model no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, H; Obuchi, T; Saito, T [Iwate University, Iwate (Japan). Faculty of Engineering

    1996-05-01

    Examination was made about the applicability of the AR model to the spatial autocorrelation (SAC) method, which analyzes the surface wave phase velocity in a microtremor, for the estimation of the underground structure. In this examination, microtremor data recorded in Morioka City, Iwate Prefecture, was used. In the SAC method, a spatial autocorrelation function with the frequency as a variable is determined from microtremor data observed by circular arrays. Then, the Bessel function is adapted to the spatial autocorrelation coefficient with the distance between seismographs as a variable for the determination of the phase velocity. The result of the AR model application in this study and the results of the conventional BPF and FFT method were compared. It was then found that the phase velocities obtained by the BPF and FFT methods were more dispersed than the same obtained by the AR model. The dispersion in the BPF method is attributed to the bandwidth used in the band-pass filter and, in the FFT method, to the impact of the bandwidth on the smoothing of the cross spectrum. 2 refs., 7 figs.

  1. Astronomically calibrated 40Ar/39Ar age for the Toba supereruption and global synchronization of late Quaternary records

    Science.gov (United States)

    Storey, Michael; Roberts, Richard G.; Saidin, Mokhtar

    2012-11-01

    The Toba supereruption in Sumatra, ∼74 thousand years (ka) ago, was the largest terrestrial volcanic event of the Quaternary. Ash and sulfate aerosols were deposited in both hemispheres, forming a time-marker horizon that can be used to synchronize late Quaternary records globally. A precise numerical age for this event has proved elusive, with dating uncertainties larger than the millennial-scale climate cycles that characterized this period. We report an astronomically calibrated 40Ar/39Ar age of 73.88 ± 0.32 ka (1σ, full external errors) for sanidine crystals extracted from Toba deposits in the Lenggong Valley, Malaysia, 350 km from the eruption source and 6 km from an archaeological site with stone artifacts buried by ash. If these artifacts were made by Homo sapiens, as has been suggested, then our age indicates that modern humans had reached Southeast Asia by ∼74 ka ago. Our 40Ar/39Ar age is an order-of-magnitude more precise than previous estimates, resolving the timing of the eruption to the middle of the cold interval between Dansgaard-Oeschger events 20 and 19, when a peak in sulfate concentration occurred as registered by Greenland ice cores. This peak is followed by a ∼10 °C drop in the Greenland surface temperature over ∼150 y, revealing the possible climatic impact of the eruption. Our 40Ar/39Ar age also provides a high-precision calibration point for other ice, marine, and terrestrial archives containing Toba sulfates and ash, facilitating their global synchronization at unprecedented resolution for a critical period in Earth and human history beyond the range of 14C dating.

  2. 40Ar/39Ar ages (600-570 Ma of the Serra do Azeite transtensional shear zone: evidence for syncontractional extension in the Cajati area, southern Ribeira belt

    Directory of Open Access Journals (Sweden)

    Rômulo Machado

    2007-12-01

    Full Text Available This paper presents 40Ar/39Ar ages of the rocks from the Serra do Azeite transtensional shear zone in the southern part of the Ribeira belt, between the States of São Paulo and Paraná, and also discusses the regional correlations and the tectonic implications for other parts of the belt. The geochronological data suggest that transtensional deformation was active between 600 and 580 Ma (hornblende and muscovite apparent ages, respectively. This time span is considerably older than previous proposals for the period of activity of these structures (520-480 Ma in the northern segment of this belt and in the Araçuaí belt. Kinematic analysis of the dated mylonites shows extensional structures with top-down movement to ESE compatible with structures found in other tectonic segments in the eastern portion of the Quadrilátero Ferrífero and in the Rio Doce Valley region. Our ages are situated in the same time interval defined for the alkaline magmatism of the Serra do Mar suite. We suggest that the regional tectonic framework was developed during continental-scale extension. This process has been coeval with convergent strain in the adjacent Neoproterozoic shear zones of the Apiaí/Ribeira and Araçuaí belts, which make up significant segments of these belts. The available data show that these structures may not be simply related to post-orogenic gravitational collapse, but must involve a more complex process probably related to dynamic balance between crustal thickening and thinning during tectonic convergence, basin formation and exhumation processes.Este trabalho apresenta idades 40Ar/39Ar de rochas da Zona de Cisalhamento Transtrativa Sinistral da Serra do Azeite, situada na parte sul do cinturão Ribeira, entre os Estados de São Paulo e Paraná, bem como discute a correlação regional e as implicações tectônicas com outras partes do cinturão. Os dados geocronológicos sugerem que a deformação extensional foi ativa entre 600 e 580 Ma

  3. Influência da matéria orgânica e do ambiente no crescimento e acúmulo de solutos em Morinda citrifolia submetida à salinidade

    Directory of Open Access Journals (Sweden)

    Maria Cristina Martins Ribeiro de Souza

    2014-09-01

    Full Text Available O Noni (Morinda citrifolia L. é uma planta tolerante aos efeitos salinos e alcalinos dos solos e desenvolve-se em regiões de clima seco ou úmido. Apesar da adaptabilidade intercontinental, ainda são poucas as informações sobre sua tolerância aos sais no solo brasileiro. Baseado no exposto, objetivou-se com o presente trabalho avaliar os efeitos da água salina no crescimento inicial do Noni. Para isso, foi conduzido um experimento em vasos de polietileno com capacidade para 20 L, em Sobral, Ceará. O delineamento estatístico adotado foi em blocos ao acaso, disposto no esquema de parcelas subsubdivididas, com 5 repetições. As parcelas foram constituídas pelos ambientes de cultivo (céu aberto e telado, as subparcelas pelos níveis de salinidade da água de irrigação (CEa: 0,3;1,5; 3,0; 4,5 e 6,0 dS m-1 e as subsubparcelas foram representadas pela ausência e presença de matéria orgânica. Aos 110 dias após a aplicação dos tratamentos (DAT, avaliaram-se: altura, massa seca da parte aérea (MSPA, da raiz (MSR, total (MST e área foliar (AF, e aos 90 (DAT os teores foliares de solutos orgânicos. Todas as variáveis de crescimento estudadas foram afetadas negativamente pela salinidade, sendo que o efeito observado a céu aberto foi mais expressivo do que no ambiente telado. A matéria orgânica não teve efeito atenuante sobre os efeitos deletérios da salinidade em plantas de noni. O acúmulo de prolina mostrou-se um sinalizador de dano causado pelo estresse, visto que os maiores acúmulos ocorreram nas plantas que sofreram maiores reduções no crescimento.

  4. 75 FR 12163 - Class E Airspace; Mountain View, AR

    Science.gov (United States)

    2010-03-15

    ...-1181; Airspace Docket No. 09-ASW-36] Class E Airspace; Mountain View, AR AGENCY: Federal Aviation... Class E airspace at Mountain View, AR. Decommissioning of the Wilcox non-directional beacon (NDB) at... View, AR. Airspace reconfiguration is necessary due to the decommissioning of the Wilcox NDB and the...

  5. Bone blood flow measured by 41Ar clearance formed by 44Ca(n,α)41Ar

    International Nuclear Information System (INIS)

    Rosenthal, M.S.; DeLuca, P.M. Jr.; Pearson, D.W.; Nickles, R.J.

    1983-01-01

    A technique to measure regional inert gas washout in bone, in vivo, by measuring 41 Ar clearance formed by fast-neutron activation of 44 Ca has been developed. Following fast-neutron irradiation of whole rats, the perfusion-limited clearance of 41 Ar was measured for both dead and living rats. The clearance rate for the live rats indicate that the bone perfusion is in the range of 3 to 20 ml/100 Argon distribution volume

  6. A pulsed plasma jet with the various Ar/N2 mixtures

    Science.gov (United States)

    Barkhordari, A.; Ganjovi, A.; Mirzaei, I.; Falahat, A.; Rostami Ravari, M. N.

    2017-12-01

    In this paper, using the Optical Emission Spectroscopy technique, the physical properties of a fabricated pulsed DBD plasma jet are studied. Ar/N2 gaseous mixture is taken as operational gas, and Ar contribution in Ar/N2 mixture is varied from 75 to 95%. Through the optical emission spectra analysis of the pulsed DBD plasma jet, the rotational, vibrational and excitation temperatures and density of electrons in plasma medium of the pulsed plasma jet are obtained. It is seen that, at the wavelength of 750.38 nm, the radiation intensity from the Ar 4p → 4 s transition increases at the higher Ar contributions in Ar/N2 mixture. It is found that, for 95% of Ar presence in the mixture, the emission intensities from argon and molecular nitrogen are higher, and the emission line intensities will increase nonlinearly. In addition, it is observed that the quenching of Ar* by N2 results in the higher intensities of N2 excited molecules. Moreover, at the higher percentages of Ar in Ar/N2 mixture, while all the plasma temperatures are increased, the plasma electron density is reduced.

  7. Acoustic resonance spectroscopy (ARS): ARS300 operations manual, software version 2.01

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-25

    Acoustic Resonance Spectroscopy (ARS) is a nondestructive evaluation technology developed at the Los Alamos National Laboratory. The ARS technique is a fast, safe, and nonintrusive technique that is particularly useful when a large number of objects need to be tested. Any physical object, whether solid, hollow, or fluid filled, has many modes of vibration. These modes of vibration, commonly referred to as the natural resonant modes or resonant frequencies, are determined by the object`s shape, size, and physical properties, such as elastic moduli, speed of sound, and density. If the object is mechanically excited at frequencies corresponding to its characteristic natural vibrational modes, a resonance effect can be observed when small excitation energies produce large amplitude vibrations in the object. At other excitation frequencies, i.e., vibrational response of the object is minimal.

  8. Etching properties of BLT films in CF4/Ar plasma

    International Nuclear Information System (INIS)

    Kim, Dong Pyo; Kim, Kyoung Tae; Kim, Chang Il

    2003-01-01

    CF 4 /Ar plasma mass content and etching rate behavior of BLT thin films were investigated in inductively coupled plasma (ICP) reactor as functions of CF 4 /Ar gas mixing ratio, rf power, and dc bias voltage. The variation of relative volume densities for F and Ar atoms were measured by the optical emission spectroscopy (OES). The etching rate as functions of Ar content showed the maximum of 803 A/min at 80 % Ar addition into CF 4 plasma. The presence of maximum etch rate may be explained by the concurrence of two etching mechanisms such as physical sputtering and chemical reaction. The role of Ar ion bombardment includes destruction of metal (Bi, La, Ti)-O bonds as well as support of chemical reaction of metals with fluorine atoms

  9. VLA radio observations of AR Scorpii

    Science.gov (United States)

    Stanway, E. R.; Marsh, T. R.; Chote, P.; Gänsicke, B. T.; Steeghs, D.; Wheatley, P. J.

    2018-03-01

    Aims: AR Scorpii is unique amongst known white dwarf binaries in showing powerful pulsations extending to radio frequencies. Here we aim to investigate the multi-frequency radio emission of AR Sco in detail, in order to constrain its origin and emission mechanisms. Methods: We present interferometric radio frequency imaging of AR Sco at 1.5, 5 and 9 GHz, analysing the total flux and polarization behaviour of this source at high time resolution (10, 3 and 3 s), across a full 3.6 h orbital period in each band. Results: We find strong modulation of the radio flux on the orbital period and the orbital sideband of the white dwarf's spin period (also known as the "beat" period). This indicates that, like the optical flux, the radio flux arises predominantly from on or near the inner surface of the M-dwarf companion star. The beat-phase pulsations of AR Sco decrease in strength with decreasing frequency. They are strongest at 9 GHz and at an orbital phase 0.5. Unlike the optical emission from this source, radio emission from AR Sco shows weak linear polarization but very strong circular polarization, reaching 30% at an orbital phase 0.8. We infer the probable existence of a non-relativistic cyclotron emission component, which dominates at low radio frequencies. Given the required magnetic fields, this also likely arises from on or near the M-dwarf. A table of the flux time series is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/611/A66

  10. 40Ar/39Ar dating of the Late Cretaceous

    International Nuclear Information System (INIS)

    Gaylor, Jonathan

    2013-01-01

    As part of the wider European GTS Next project, I propose new constraints on the ages of the Late Cretaceous, derived from a multitude of geochronological techniques, and successful stratigraphic interpretations from Canada and Japan. In the Western Canada Sedimentary Basin, we propose a new constraint on the age of the K/Pg boundary in the Red Deer River section (Alberta, Canada). We were able to cyclo-stratigraphically tune sediments in a non-marine, fluvial environment utilising high-resolution proxy records suggesting a 11-12 precession related cyclicity. Assuming the 40 Ar/ 39 Ar method is inter-calibrated with the cyclo-stratigraphy, the apparent age for C29r suggests that the K/Pg boundary falls between eccentricity maxima and minima, yielding an age of the C29r between 65.89 ± 0.08 and 66.30 ± 0.08 Ma. Assuming that the bundle containing the coal horizon represents a precession cycle, the K/Pg boundary is within the analytical uncertainty of the youngest zircon population achieving a revised age for the K/Pg boundary as 65.75 ± 0.06 Ma. The Campanian - Maastrichtian boundary is preserved in the sedimentary succession of the Horseshoe Canyon Formation and has been placed 8 m below Coal nr. 10. Cyclo-stratigraphic studies show that the formation of these depositional sequences (alternations) of all scales are influenced directly by sea-level changes due to precession but more dominated by eccentricity cycles proved in the cyclo-stratigraphic framework and is mainly controlled by sand horizons, which have been related by auto-cyclicity in a dynamic sedimentary setting. Our work shows that the Campanian - Maastrichtian boundary in the Western Canada Sedimentary Basin coincides with 2.5 eccentricity cycles above the youngest zircon age population at the bottom of the section and 4.9 Myr before the Cretaceous - Palaeogene boundary (K/Pg), and thus corresponds to an absolute age of 70.65 ± 0.09 Ma producing an 1.4 Myr younger age than recent published ages

  11. Programação de entretenimento não ficcional na TV aberta brasileira: levantamento do ao vivo na TV Globo, TV Record e SBT

    Directory of Open Access Journals (Sweden)

    Julio Cesar Fernandes

    2017-06-01

    Full Text Available A TV aberta tem uma penetração muito grande no Brasil e, tradicionalmente, ainda é referência em produção televisiva. Os gêneros e formatos consagrados permanecem há décadas na grade nas emissoras, sem grandes modificações. O objetivo deste estudo é fazer um levantamento da programação de entretenimento não ficcional das três maiores redes nacionais abertas do País, em audiência: TV Globo, TV Record e SBT. Ao categorizar os conteúdos desses programas, é possível analisar a quantidade de produção feita, de fato, ao vivo e o impacto dessa linguagem na sobrevivência da mídia, principalmente em um momento em que se discute o futuro da TV tradicional por conta da disseminação de telas e o avanço da internet. Ao todo, mais de 120 horas de produção foram gravadas, decupadas e analisadas, para se traçar uma situação atual da TV aberta no País e seu futuro.DOI: http://dx.doi.org/10.21882/ruc.v5i8.679 Recebido em: 14/04/2017 Aceito em: 20/06/2017  

  12. Argon in hornblende, biotite and muscovite in geologic cooling - Ar-40/Ar-39-investigations

    International Nuclear Information System (INIS)

    Rittman, K.L.

    1984-01-01

    The results of the Ar-40/Ar-39 studies are discussed under the aspect of whether the age data of the minerals indicate a cooling process. The author hopes that isotope dating of minerals with different closing temperatures will describe the temperature/time history of an area in the temperature range of 600 to 200 0 C. The findings are analyzed under three aspects: How much do they contribute to the initial methodological question, what do they contribute to the regional geology of the areas investigated, and in what respects do they extent the present knowledge of the geochronological analysis, i.e. its techniques and interpretation. (orig.) [de

  13. 40Ar/39Ar laster fusion and K-Ar ages from Lathrop Wells, Nevada, and Cima, California: The age of the latest volcanic activity in the Yucca Mountain area

    International Nuclear Information System (INIS)

    Turrin, B.D.; Champion, D.E.

    1991-01-01

    K-Ar and 40 Ar/ 39 Ar ages from the Lathrop Wells volcanic center, Nevada, and from the Cima volcanic field, California, indicate that the recently reported 20-ka age estimate for the Lathrop Wells volcanic center is incorrect. Instead, an age of 119 ± 11 to 141 ± 10 ka is indicated for the Lathrop Wells volcanic center. This age corrected is concordant with the ages determined by two independent isotopic geochronometric techniques and with the stratigraphy of surficial deposits in the Yucca Mountain region. In addition, paleomagnetic data and radiometric age data indicate only two volcanic events at the Lathrop Wells volcanic center that are probably closely linked in time, not as many as five as recently reported. 32 refs., 2 figs., 2 tabs

  14. AR Expression in Breast Cancer CTCs Associates with Bone Metastases.

    Science.gov (United States)

    Aceto, Nicola; Bardia, Aditya; Wittner, Ben S; Donaldson, Maria C; O'Keefe, Ryan; Engstrom, Amanda; Bersani, Francesca; Zheng, Yu; Comaills, Valentine; Niederhoffer, Kira; Zhu, Huili; Mackenzie, Olivia; Shioda, Toshi; Sgroi, Dennis; Kapur, Ravi; Ting, David T; Moy, Beverly; Ramaswamy, Sridhar; Toner, Mehmet; Haber, Daniel A; Maheswaran, Shyamala

    2018-04-01

    Molecular drivers underlying bone metastases in human cancer are not well understood, in part due to constraints in bone tissue sampling. Here, RNA sequencing was performed of circulating tumor cells (CTC) isolated from blood samples of women with metastatic estrogen receptor (ER) + breast cancer, comparing cases with progression in bone versus visceral organs. Among the activated cellular pathways in CTCs from bone-predominant breast cancer is androgen receptor (AR) signaling. AR gene expression is evident, as is its constitutively active splice variant AR-v7. AR expression within CTCs is correlated with the duration of treatment with aromatase inhibitors, suggesting that it contributes to acquired resistance to endocrine therapy. In an established breast cancer xenograft model, a bone-tropic derivative displays increased AR expression, whose genetic or pharmacologic suppression reduces metastases to bone but not to lungs. Together, these observations identify AR signaling in CTCs from women with bone-predominant ER + breast cancer, and provide a rationale for testing androgen inhibitors in this subset of patients. Implications: This study highlights a role for the AR in breast cancer bone metastasis, and suggests that therapeutic targeting of the AR may benefit patients with metastatic breast cancer. Mol Cancer Res; 16(4); 720-7. ©2018 AACR . ©2018 American Association for Cancer Research.

  15. Jumps in binomial AR(1) processes

    OpenAIRE

    Weiß , Christian H.

    2009-01-01

    Abstract We consider the binomial AR(1) model for serially dependent processes of binomial counts. After a review of its definition and known properties, we investigate marginal and serial properties of jumps in such processes. Based on these results, we propose the jumps control chart for monitoring a binomial AR(1) process. We show how to evaluate the performance of this control chart and give design recommendations. correspondance: Tel.: +49 931 31 84968; ...

  16. Teste de desencadeamento aberto no diagnóstico de alergia à proteína do leite de vaca Open challenge for the diagnosis of cow's milk protein allergy

    Directory of Open Access Journals (Sweden)

    Fernanda Ferreira Correa

    2010-04-01

    Full Text Available OBJETIVO: Relatar os resultados de testes de desencadeamento aplicados em crianças alimentadas com dieta de exclusão das proteínas do leite de vaca. DESCRIÇÃO: Estudo transversal que avaliou testes de desencadeamento oral aberto, com leite de vaca, realizados sob supervisão em ambiente hospitalar por 2,5 horas e ambulatoriamente por 30 dias quando não ocorreu reação imediata. Foram incluídos 121 pacientes, com idades entre 4 e 95 meses. O teste de desencadeamento com leite de vaca foi positivo em 28 (23,1% pacientes. Manifestação clínica de alergia ao leite de vaca diferente da apresentada por ocasião da suspeita diagnóstica ocorreu em 12 (42,9% pacientes com desencadeamento positivo. O desencadeamento positivo foi mais frequente (p = 0,042 nos pacientes alimentados com fórmulas extensamente hidrolisadas ou de aminoácidos (30,3% quando comparados com os alimentados com outras dietas de exclusão (14,5%. CONCLUSÃO: O teste de desencadeamento permitiu que fosse suspensa a dieta de exclusão de grande parte dos pacientes.OBJECTIVES: To report the results of open challenge tests performed in children fed with cow's milk-free diet. DESCRIPTIONS: Cross-sectional study evaluating cow's milk open challenge performed under supervision in a hospital setting during 2.5 hours and ambulatory follow-up for 30 days when no immediate reaction occurred. One hundred and twenty-one patients were included, with ages between 4 and 95 months. Cow's milk open challenge tests were positive in 28 patients (23.1%. A clinical manifestation of cow's milk allergy different from the one presented at diagnosis occurred in 12 (24.9% patients with positive challenge. Positive challenge was more frequent (p = 0.042 in patients fed with extensively hydrolyzed formulae or amino acid-based formulae (30.3% when compared to those fed with other exclusion diets (14.5%. CONCLUSION: Open challenge allowed the interruption of exclusion diet in a significant proportion

  17. The ChArMEx database

    Science.gov (United States)

    Ferré, Hélène; Descloitres, Jacques; Fleury, Laurence; Boichard, Jean-Luc; Brissebrat, Guillaume; Focsa, Loredana; Henriot, Nicolas; Mastrorillo, Laurence; Mière, Arnaud; Vermeulen, Anne

    2013-04-01

    The Chemistry-Aerosol Mediterranean Experiment (ChArMEx, http://charmex.lsce.ipsl.fr/) aims at a scientific assessment of the present and future state of the atmospheric environment in the Mediterranean Basin, and of its impacts on the regional climate, air quality, and marine biogeochemistry. The project includes long term monitoring of environmental parameters, intensive field campaigns, use of satellite data and modelling studies. Therefore ChARMEx scientists produce and need to access a wide diversity of data. In this context, the objective of the database task is to organize data management, distribution system and services such as facilitating the exchange of information and stimulating the collaboration between researchers within the ChArMEx community, and beyond. The database relies on a strong collaboration between OMP and ICARE data centres and falls within the scope of the Mediterranean Integrated Studies at Regional And Locals Scales (MISTRALS) program data portal. All the data produced by or of interest for the ChArMEx community will be documented in the data catalogue and accessible through the database website: http://mistrals.sedoo.fr/ChArMEx. The database website offers different tools: - A registration procedure which enables any scientist to accept the data policy and apply for a user database account. - Forms to document observations or products that will be provided to the database in compliance with metadata international standards (ISO 19115-19139; INSPIRE; Global Change Master Directory Thesaurus). - A search tool to browse the catalogue using thematic, geographic and/or temporal criteria. - Sorted lists of the datasets by thematic keywords, by measured parameters, by instruments or by platform type. - A shopping-cart web interface to order in situ data files. At present datasets from the background monitoring station of Ersa, Cape Corsica and from the 2012 ChArMEx pre-campaign are available. - A user-friendly access to satellite products

  18. A identidade no mundo das religiões: a região fronteiriça

    Directory of Open Access Journals (Sweden)

    José Maria da Silva

    2009-05-01

    Full Text Available O tema em questão aborda, com base nas reflexões realizadas pelos teólogos inclusivistas abertos, as relações existentes de incompatibilidade ou compatibilidade entre a identidade religiosa cristã e a abertura ao mundo pluralista religioso pós-moderno. Constantemente presentes, como pilares do arcabouço teórico utilizado, aparecerão as reflexões daqueles estudiosos que, cônscios da realidade plural do mundo religioso contemporâneo, e não contentes com uma identidade amarrada somente à tradição e aos dogmas iniciais, desbravam um caminho ao mesmo tempo aberto às demais religiões e com identidade própria. O objetivo principal destes escritos é mostrar a possibilidade de uma reflexão localizada religiosamente e em diálogo com as diversas expressões do pluralismo religioso hodierno.Palavras-chave: Identidade; Religiões; Paradigma; Fronteira; Pós-modernidade.ABSTRACTThis article considers relations of comptability or incomptability between the Christian religion identity and postmodern religious pluralism, with basis on inclusivist theologians’ reflections. Those scholars’ reflections are constantly present as theoretical pillars, for their awareness of the plural reality of the modern religious world, as well as for their disregard for an identity constrained by tradition and the initial dogmas, which led them towards a road at the same time open to other religions and with an identitiy of its own. Those writings aim mainly at pointing out the possibility of a religious reflection open to contact and dialogue with the various expressions of modern religious pluralism.Key words: Identity; Religions; Paradigm; Borderline; Post-modernity.

  19. Single-electron capture into Ar+ excited states in Ar2 + Na collision below 12 keV, 1

    International Nuclear Information System (INIS)

    Matsumoto, Atsushi; Tsurubuchi, Seiji; Okuno, Kazuhiko; Ohtani, Shunsuke; Iwai, Tsuruji.

    1979-08-01

    Emission spectra between 2800 and 6000 A have been observed at the ionic energies from 0.2 to 12 keV. Absolute measurements of emission cross-sections have been made for the emission lines coming from ArII excited states at 4 and 8 keV with a crossed-beam technique. Processes of single-electron capture into the ArII 4p- and 4p'-states, with exothermicity of a few eV, take place dominantly (--10 15 cm 2 ), while the endothermic processes producing ArII in the 4d- and 5s-states occur with small cross-sections. Sum of the cross-sections for electron capture into the excited states observed is comparable with the total single-electron capture cross-section estimated from attenuation measurements of ion currents. Possible errors and uncertainties are discussed. (author)

  20. Single-electron capture into Ar+ excited states in Ar2++Na collision below 12 keV, 1

    International Nuclear Information System (INIS)

    Matsumoto, Atsushi; Tsurubuchi, Seiji; Iwai, Tsuruji; Ohtani, Shunsuke; Okuno, Kazuhiko

    1980-01-01

    Emission spectra between 2800 and 6000 A have been observed at the ionic energies from 0.2 to 12 keV. Absolute measurements of emission cross-sections have been made for the emission lines coming from ArII excited states at 4 and 8 keV with a crossed-beam technique. Processes of single-electron capture into the ArII 4p- and 4p'-states, with exothermicity of a few eV, take place dominantly (--10 -15 cm 2 ), while the endothermic processes producing ArII in the 4d- and 5s-states occur with small cross-sections. Sum of the cross-sections for electron capture into the excited states observed is comparable with the total single-electron capture cross-section estimated from attenuation measurements of ion currents. Possible errors and uncertainties are discussed. (author)

  1. Measurements of the 40Ar(n, γ41Ar radiative-capture cross section between 0.4 and 14.8 MeV

    Directory of Open Access Journals (Sweden)

    Megha Bhike

    2014-09-01

    Full Text Available The 40Ar(n, γ41Ar neutron capture cross section has been measured between 0.4 and 14.8 MeV neutron energy using the activation technique. The data are important for estimating backgrounds in argon-based neutrino and dark-matter detectors and in the neutrino-less double-beta decay search GERDA, which uses liquid argon as cooling and shielding medium. For the first time the 40Ar(n, γ41Ar cross section has been measured for neutron energies above 1 MeV. Our results are compared to the evaluation ENDF/B-VII.1 and the calculated prediction TENDL-2013. The latter agrees very well with the present results.

  2. Characteristics of violent collisions in Ar-induced reactions at intermediaire energies

    International Nuclear Information System (INIS)

    Rivet, M.F.; Borderie, B.

    1984-01-01

    We report on two experiments performed with the Ganil facility using the 27 MeV/u Ar beam. The first one concerns an intermediate mass system, Ar + Ag. For the second one a heavier fissile system, Ar + U, was chosen. For Ar + Ag information about fusion requires the measurements of evaporation residues and fission. In the Ar + U reaction, most of the collisions lead to fission. The violence of the collision is therefore determined from the correlation angle of the coincidence fission fragments

  3. Levels in 45K and 46K excited by the β decay of 45Ar and 46Ar

    International Nuclear Information System (INIS)

    Huck, A.; Klotz, G.; Knipper, A.; Miehe, C.; Walter, G.

    1979-01-01

    The nuclides 45 Ar and 46 Ar have been produced by spallation reactions on vanadium targets at Esub(p)=600MeV. The subsequent decays to 45 K and 46 K states have been studied. An intensity of 98.6+-0.6% was measured for the β transition of the 1.94MeV state in 46 K. A decay scheme involving 13 β branches has been established for 45 Ar, and the corresponding log values have been deduced. Eleven states are reported for the first time in the decay scheme of 45 Ar 1.42, 1.47, 1.72, 2.52, 2.57, 2.75, 3.31, 3.99, 4.04, 4.36 and 4.57MeV. From the lifetime, tau=4.6+-0.6ns, deduced from γ-γ delayed coincidences, the angular momentum of the 1081keV level has been established as (7/2) - on the basis of the transition strength of its γ decay. A survey on the 1fsub(7/2)→1dsub(3/2)M2 transition in odd K nuclei is presented and the observed hindrance factors are discussed

  4. Sensibility of different wheat varieties (strains) to Ar+ implantation

    International Nuclear Information System (INIS)

    Cui Huanhu; Jing Hua; Ma Aiping; Kang Xiuli; Yang Liping; Huang Mingjing; Ma Buzhou; Shanxi Academy of Agricultural Sciences, Taiyuan

    2005-01-01

    The sensibility of different wheat varieties (strains) to Ar + implantation was studied. The results showed that the survival rate of 21 wheat varieties (strains) at the dose of 6 x 10 16 Ar + /cm 2 could be divided into five groups: surplus sensitive varieties (strains), sensitive varieties (strains), transitional varieties (strains), obtuse varieties (strains) and surplus obtuse varieties (strains). The sensibility of wheat varieties (strains) to Ar + injection is high-moisture-fertility wheat varieties (strains) > medium-moisture-fertility wheat varieties (strains) > dry land wheat varieties (strains). The study has provided theoretical basis in induced mutation medial lethal dose of different wheat varieties (strains) to Ar + implantation. (authors)

  5. AR-v7 protein expression is regulated by protein kinase and phosphatase

    Science.gov (United States)

    Li, Yinan; Xie, Ning; Gleave, Martin E.; Rennie, Paul S.; Dong, Xuesen

    2015-01-01

    Failure of androgen-targeted therapy and progression of castration-resistant prostate cancer (CRPC) are often attributed to sustained expression of the androgen receptor (AR) and its major splice variant, AR-v7. Although the new generation of anti-androgens such as enzalutamide effectively inhibits AR activity, accumulating pre-clinical and clinical evidence indicates that AR-v7 remains constitutively active in driving CRPC progression. However, molecular mechanisms which control AR-v7 protein expression remain unclear. We apply multiple prostate cancer cell models to demonstrate that enzalutamide induces differential activation of protein phosphatase-1 (PP-1) and Akt kinase depending on the gene context of cancer cells. The balance between PP-1 and Akt activation governs AR phosphorylation status and activation of the Mdm2 ubiquitin ligase. Mdm2 recognizes phosphorylated serine 213 of AR-v7, and induces AR-v7 ubiquitination and protein degradation. These findings highlight the decisive roles of PP-1 and Akt for AR-v7 protein expression and activities when AR is functionally blocked. PMID:26378044

  6. Dating quartz: Ar/Ar analyses of coexisting muscovite and fluid inclusion - rich quartz from paleocene amorphic aureole

    International Nuclear Information System (INIS)

    Matthews, S.J.; Perez de Arce, C.; Cornejo, P.; Cuitino, L; Klein, J

    2001-01-01

    We present Ar/Ar total fusion and step-heating data for coexisting muscovite and white quartz from the metamorphic aureole of the Lower Paleocene La Copiapina Pluton, 6 km south of Inca de Oro, III Region, Chile. The pluton intrudes the upper clastic sedimentary member of the Punta del Cobre Group (Upper Jurassic - Lower Cretaceous) and the calcareous sedimentary rocks of the Chanarcillo Group (Neocomian), and comprises fine to coarse grained pyroxene-hornblende-biotite quartz diorites and monzodiorites. Its emplacement was controlled on its north-western side by a subvertical NE-trending fault, along which were developed vertically banded skarns (skarn mylonite), suggesting syntectonic intrusion. Biotite K-Ar ages for the pluton fall in the range 61-63 Ma, relating it to a latest Cretaceous to Lowest Paleocene syn-compressional intrusive belt which is present in the area (Matthews and Cornejo, 2000). A metamorphic / metasomatic aureole is developed within the sandstones of the Punta del Cobre Group, on the extreme northern limit of the pluton. In this area, the sedimentary rocks have been replaced by quartz-sericite and quartz-muscovite assemblages, with minor hematite and tourmaline, and late supergene kaolinite and pyrophyllite. A coarse muscovite-quartz-tourmaline-hematite assemblage is developed in and around older (early Upper Cretaceous) andesitic dykes, in the form of replacement / fracture fill veins and replacement zones. Further from the contact with the pluton, fine-grained quartz-sericite rock with coarser muscovite-rich replacement veins represents the dominant lithology. Quartz in the coarse replacement rock is very rich in fluid inclusions. Primary inclusions are mainly of two coexisting types; bi-phase (liquid and gas bubble) and tri-phase (liquid, gas bubble and halite crystal), indicating that the quartz formed in the presence of a boiling fluid. Some inclusions also contain sylvite and occasional hematite daughter crystals. Secondary inclusions

  7. 75 FR 68416 - Establishment of Class E Airspace; Berryville, AR

    Science.gov (United States)

    2010-11-08

    ...-0690; Airspace Docket No. 10-ASW-2] Establishment of Class E Airspace; Berryville, AR AGENCY: Federal... for Berryville, AR, to accommodate Area Navigation (RNAV) Standard Instrument Approach Procedures (SIAP) at Carroll County Airport, Berryville, AR. The FAA is taking this action to enhance the safety...

  8. 76 FR 73505 - Establishment of Class E Airspace; Nashville, AR

    Science.gov (United States)

    2011-11-29

    ...-0497; Airspace Docket No. 11-ASW-4] Establishment of Class E Airspace; Nashville, AR AGENCY: Federal... for Nashville, AR, to accommodate new Area Navigation (RNAV) Standard Instrument Approach Procedures... a notice of proposed rulemaking to amend Class E airspace for Nashville, AR, creating additional...

  9. 75 FR 29655 - Amendment of Class E Airspace; Batesville, AR

    Science.gov (United States)

    2010-05-27

    ...-1177; Airspace Docket No. 09-ASW-34] Amendment of Class E Airspace; Batesville, AR AGENCY: Federal... Batesville, AR. Decommissioning of the Independence County non-directional beacon (NDB) at Batesville Regional Airport, Batesville, AR, has made this action necessary to enhance the safety and management of...

  10. Influence of Ar addition on ozone generation in nonthermal plasmas

    International Nuclear Information System (INIS)

    Chen, Hsin Liang; Lee, How Ming; Chen, Shiaw Huei; Wei, Ta Chin; Chang, Moo Been

    2010-01-01

    Inconsistency regarding the influence of Ar addition on ozone generation in a corona discharge has been found in relevant studies. Unlike in the literature to date, a dielectric barrier discharge (DBD) reactor is adopted in this study. In addition to clarifying whether using Ar as an additive would lead to different types of behavior in a DBD and a corona discharge, this study is also motivated to explore the possible causes leading to the inconsistency. The experimental results show that adding Ar into the O 2 plasma would lead to the same influence on ozone generation in the DBD and corona discharge. Moreover, all types of controversial behavior caused by Ar addition reported in the relevant literature are observed in this study as well, indicating that the results of this study are comprehensive enough to interpret the inconsistency. By examining the experimental results in detail, it is found that the controversial influences of Ar addition on ozone generation were found using different assumptions. At a fixed applied voltage, the ozone generation might increase as the Ar concentration is increased, which results from a higher discharge power. Nevertheless, for a certain specific input energy (the ratio of discharge power to gas flow rate), the ozone concentration is lower as the Ar concentration is increased. Therefore, adding Ar is not a good way to enhance ozone generation from an economic point of view.

  11. Contribution of the 40Ar/39Ar method to improve Middle-Pleistocene archaeological/palaeontological sites from the Italian Peninsula

    Science.gov (United States)

    Nomade, Sebastien, ,, Dr.; Pereira, MSc. Alison; voinchet, Pierre, ,, Dr.; Bahain, Jean-Jacques, ,, Dr.; Aureli, Daniele, ,, Dr.; Arzarello, Marta, ,, Dr.; Anzidei, Anna-Paola, ,, Dr.; Biddittu, Italo, ,, Dr.; Bulgarelli, Maria-Grazia, ,, Dr.; Falguères, Christophe, ,, Dr.; Giaccio, Biagio, ,, Dr.; Guillou, Hervé, ,, Dr.; Manzi, Gorgio, ,, Dr.; Moncel, Marie-Hélène, ,, Dr.; Nicoud, Elisa, ,, Dr.; Pagli, Maria, ,, Dr.; Parenti, Fabio, ,, Dr.; Peretto, Carlo, ,, Dr.; Piperno, Marcello, ,, Dr.; Rocca, Roxane, ,, Dr.

    2017-04-01

    European Middle-Pleistocene archaeological and/or paleontological sites lack a unified and precise chronological framework. Despite recent efforts mostly focused on methods such as OSL, ESR/U-series or cosmogenic nuclides, the age of numerous sites from this period fundamentally still relies on qualitative and speculative palaeoenvironmental and/or palaeontological/palaeoanthropological considerations. The lack of robust chronologies, along with the scarcity of human fossils, prevent coherent correlations between European sites which in turn limits our understanding of human diffusion dynamics, understand techno-cultural evolution or correlate archaeological sites with palaeoclimatic and environmental records. With the goal of providing an accurate and precise chronological framework based on a multi-method approach, a research network including geochronologists, archaeologist and paleoanthropologists from various French and Italian institutions launched in 2010 a wide study of Middle-Pleistocene archaeological sites of central and southern Italy. This study combining the 39Ar/40Ar method with palaeo-dosimetric methods applied to European sites in the age range of 700 ka to 300 ka is unprecedented. In parallel, a large effort has been done to improve the regional Middle-Pleistocene tephrostratigraphic database through a massive application of both high-precision 40Ar/39Ar geochronological and geochemical investigations. We illustrate our approach and results in addressing several key-sites such as Notarchirico, Valle Giumentina; Ceprano-Campogrande and La Polledrara di Cecanibbio. The accurate and precise chronological framework we built permits us to replace all the investigated archaeological and palaeontological records into a coherent climatic and environmental context. Furthermore, our work provides the opportunity to compare lithic industries from a technical and evolutionary point of view within a homogeneous temporal frame. These preliminary results border

  12. Problems in the K-Ar dating of Quaternary volcanic rocks younger than 1 Ma

    International Nuclear Information System (INIS)

    Takaoka, Nobuo

    1989-01-01

    The assumption that the 40 Ar/ 36 Ar ratio of Ar trapped in volcanic rocks at eruption is atmospheric often gives a large systematic error in the K-Ar dating of Quaternary volcanic rocks younger than 1 Ma. There are two possible sources of error, the existence of excess Ar and mass-fractionated, initial Ar. The major source of excess Ar is supposed to be magma. The 40 Ar/ 36 Ar ratio for magmatic Ar in the North-East Japan arc is tentatively estimated to be 340±10 from measurements of Ar in large phenocrysts separated from Quaternary volcanic rocks. Separation of phenocrysts is the most effective to decrease the systematic error caused by excess Ar. The mass-fractionation of initial Ar should give the 38 Ar/ 36 Ar ratio which was changed from the atmospheric ratio. This can be checked by determining the 38 Ar/ 36 Ar ratio in samples. Since the systematic error caused by the mass-fractionated, initial Ar increases greatly with the increasing atmospheric Ar correction, it is important to correct the result for the mass-fractionation. Correction formulae are given. The error sources other than those mentioned above are uncertainty in the blank correction and instabilities in the sensitivity of spectrometer and the Ar isotopic ratio measurement. In order to increase accuracy of the K-Ar age obtained, to check the systematic errors by measuring samples together with standard samples is of great importance in the K-Ar dating of very young volcanic rocks. (author)

  13. arXiv ARS Leptogenesis

    CERN Document Server

    Drewes, M.; Hernandez, P.; Kekic, M.; Lopez-Pavon, J.; Racker, J.; Rius, N.; Salvado, J.; Teresi, D.

    2018-02-28

    We review the current status of the leptogenesis scenario originally proposed by Akhmedov, Rubakov and Smirnov (ARS). It takes place in the parametric regime where the right-handed neutrinos are at the electroweak scale or below and the CP-violating effects are induced by the coherent superposition of different right-handed mass eigenstates. Two main theoretical approaches to derive quantum kinetic equations, the Hamiltonian time evolution as well as the Closed-Time-Path technique are presented, and we discuss their relations. For scenarios with two right-handed neutrinos, we chart the viable parameter space. Both, a Bayesian analysis, that determines the most likely configurations for viable leptogenesis given different variants of flat priors, and a determination of the maximally allowed mixing between the light, mostly left-handed, and heavy, mostly right-handed, neutrino states are discussed. Rephasing invariants are shown to be a useful tool to classify and to understand various distinct contributions to...

  14. 40Ar/39Ar incremental-release ages of biotite from a progressively remetamorphosed Archean basement terrane in southwestern Labrador

    International Nuclear Information System (INIS)

    Dallmeyer, R.D.

    1982-01-01

    Gneisses within Archean basement terrane adjacent to the southwestern portion of the Labrador Trough were variably retrograded during a regional metamorphism of Grenville age (ca. 1000 Ma). Bioties from non-retrograded segments of the gneiss terrane record 40 Ar/ 39 Ar plateau and isochron ages which date times of cooling following an episode of the Kenoran orogeny (2376-2391 Ma). A suite of gneiss samples displaying varying degrees of retrograde alteration was collected across the Grenville metamorphic gradient. Bioties in these samples show no petrographic evidence of retrograde alteration, however they do record internally discordant 40 Ar/ 39 Ar age spectra. Although the extent of internal discordance is variable, the overall character of the release patterns is similar with younger apparent ages recorded in intermediate-temperature gas fractions. The total-gas dates range from 2257+-27 Ma (northwest) to 1751+-23 Ma (southeast), suggesting that variable quantities of radiogenic argon were lost from the Archean biotites during Grenville metamorphism. The 'saddle-shaped' nature of the discordant spectra indicates that argon loss was not accomplished through single-stage, volume diffusion processes. (orig./ME)

  15. Ar-40/Ar-39 age determinations for the Rotoiti eruption, New Zealand

    Science.gov (United States)

    Flude, S.; Storey, M.

    2013-12-01

    The contemporaneous Rotoiti and Earthquake Flat ignimbrites, erupted from the Taupo Volcanic zone, New Zealand, form a distinctive tephrostratigraphic horizon in the Southern Pacific. Radioisotopic dating results for these eruptions remain controversial, with published ages ranging from 35.1 × 2.8 ka [1] to 71 × 6 ka [2], with 61.0 × 1.5 ka [3] often being cited as the most widely accepted age. These eruptions are difficult to date as their age is near the limit for various radiometric dating techniques, which are complicated by a large proportion of inherited material (xenocrysts) and a lack of phases suitable for dating. Glass-bearing plutonic blocks erupted with the Rotoiti and Earthquake Flat ignimbrites have previously been interpreted as deriving from a slowly cooled and incompletely solidified magma body that was sampled by the eruptions. They contain large vugs lined with euhedral quartz, sanidine and biotite crystals, indicating that these crystals grew in a gas or aqueous fluid rich environment and are interpreted to have formed shortly before or during eruption. Here we will present Ar-40/Ar-39 ages for sanidines and biotites extracted from vugs in lithic blocks erupted as part of the Earthquake Flat ignimbrite. We show that, even for vug-lining material, inherited ages remain a problem and are the likely source of the wide variation in published radiometric ages. Nevertheless, many of the Ar-40/Ar-39 ages are much younger than the 61 ka age [3] and are more consistent with the recent stratigraphic, C-14 and U-238/Th-230+(U-Th)/He ages that have been suggested (e.g. [4,5]). 1. Whitehead, N. & Ditchburn, R. New Zealand Journal of Geology and Geophysics 37, 381-383 (1994). 2. Ota, Y., Omura, A. & Iwata, H. New Zealand Journal of Geology and Geophysics 32, 327-331 (1989). 3. Wilson, C. J. N. et al. Quaternary Science Reviews 26, 1861-1870 (2007). 4. Molloy, C., Shane, P. & Augustinus, P. Geological Society of America Bulletin 121, 1666-1677 (2009). 5

  16. 78 FR 41838 - Establishment of Class E Airspace; Colt, AR

    Science.gov (United States)

    2013-07-12

    ...-1281; Airspace Docket No. 12-ASW-13] Establishment of Class E Airspace; Colt, AR AGENCY: Federal... at Colt, AR. Controlled airspace is necessary to accommodate new Area Navigation (RNAV) Standard... Federal Register a notice of proposed rulemaking (NPRM) to establish Class E airspace for the Colt, AR...

  17. 75 FR 29657 - Establishment of Class E Airspace; Marianna, AR

    Science.gov (United States)

    2010-05-27

    ...-1167; Airspace Docket No. 09-ASW-33] Establishment of Class E Airspace; Marianna, AR AGENCY: Federal... for Marianna, AR to accommodate Area Navigation (RNAV) Standard Instrument Approach Procedures (SIAPs) at Marianna/Lee County Airport--Steve Edwards Field, Marianna, AR. The FAA is taking this action to...

  18. 75 FR 29656 - Amendment of Class E Airspace; Magnolia, AR

    Science.gov (United States)

    2010-05-27

    ...-1179; Airspace Docket No. 09-ASW-35] Amendment of Class E Airspace; Magnolia, AR AGENCY: Federal... airspace for Magnolia, AR. Decommissioning of the Magnolia non-directional beacon (NDB) at Magnolia Municipal Airport, Magnolia, AR has made this action necessary to enhance the safety and management of...

  19. 75 FR 37291 - Amendment of Class E Airspace; Osceola, AR

    Science.gov (United States)

    2010-06-29

    ...-1183; Airspace Docket No. 09-ASW-38] Amendment of Class E Airspace; Osceola, AR AGENCY: Federal... Osceola, AR. Decommissioning of the Osceola non-directional beacon (NDB) at Osceola Municipal Airport has... rulemaking to amend Class E airspace for Osceola, AR, reconfiguring controlled airspace at Osceola Municipal...

  20. Integração analítica da micro e da macroeconomia: algumas reflexões teórico-metodológicas

    Directory of Open Access Journals (Sweden)

    Fernanda Graziella Cardoso

    Full Text Available Resumo Partindo de um esforço de síntese de contribuições teóricas alternativas ao mainstream da Economia - Simon, Keynes e pós-keynesianos, Kalecki, Schumpeter e neoschumpeterianos e abordagem da complexidade -, o presente artigo discute algumas das limitações ao progresso da Ciência Econômica, enquanto ciência e base para formulação de políticas, impostas por um enfoque baseado nas premissas da maximização e do equilíbrio. Sugerem-se, desse modo, algumas das possibilidades de avanço deixadas em aberto por meio da superação dessas premissas, apontando especialmente para aquela que seria uma abordagem interessante ao objeto da Economia, a micromacrodinâmica, levando em consideração seu caráter dinâmico e complexo.

  1. Exhumation history of the NW Indian Himalaya revealed by fission track and 40Ar/39Ar ages

    Science.gov (United States)

    Schlup, Micha; Steck, Albrecht; Carter, Andrew; Cosca, Michael; Epard, Jean-Luc; Hunziker, Johannes

    2011-01-01

    New fission track and Ar/Ar geochronological data provide time constraints on the exhumation history of the Himalayan nappes in the Mandi (Beas valley) — Tso Morari transect of the NW Indian Himalaya. Results from this and previous studies suggest that the SW-directed North Himalayan nappes were emplaced by detachment from the underthrusted upper Indian crust by 55 Ma and metamorphosed by ca. 48–40 Ma. The nappe stack was subsequently exhumed to shallow upper crustal depths (

  2. Absolute timing of sulfide and gold mineralization: A comparison of Re-Os molybdenite and Ar-Ar mica methods from the Tintina Gold Belt, Alaska

    Science.gov (United States)

    Selby, D.; Creaser, R.A.; Hart, C.J.R.; Rombach, C.S.; Thompson, J.F.H.; Smith, Moira T.; Bakke, A.A.; Goldfarb, R.J.

    2002-01-01

    New Re-Os molybdenite dates from two lode gold deposits of the Tintina Gold Belt, Alaska, provide direct timing constraints for sulfide and gold mineralization. At Fort Knox, the Re-Os molybdenite date is identical to the U-Pb zircon age for the host intrusion, supporting an intrusive-related origin for the deposit. However, 40Ar/39Ar dates from hydrothermal and igneous mica are considerably younger. At the Pogo deposit, Re-Os molybdenite dates are also much older than 40Ar/39Ar dates from hydrothermal mica, but dissimilar to the age of local granites. These age relationships indicate that the Re-Os molybdenite method records the timing of sulfide and gold mineralization, whereas much younger 40Ar/39Ar dates are affected by post-ore thermal events, slow cooling, and/or systemic analytical effects. The results of this study complement a growing body of evidence to indicate that the Re-Os chronometer in molybdenite can be an accurate and robust tool for establishing timing relations in ore systems.

  3. El papel de la institución en el escoger, acoger y acompañar al profesor universitario O papel da instituição para escolher, acolher e acompanhar ao professor universitário The role of the institution in choosing, receiving and chaperone professors in the university

    Directory of Open Access Journals (Sweden)

    Maria de Lourdes da Silva Marques Ferreira

    2011-03-01

    Full Text Available Objetivo. Analizar el papel de la institución en el proceso de escoger, acoger y acompañar al profesor universitario. Metodología. Estudio cualitativo cuyo cuerpo de análisis estuvo compuesto por 32 participaciones en un foro temático de un grupo de nueve profesionales del área de la salud. Resultados. Después de la contratación del profesor es necesario acogerlo y acompañarlo. Los profesores con mayor tiempo en la institución representan un papel importante en la acogida del nuevo compañero. El proceso de acompañamiento es una oportunidad para cambios y redefinición de reglas y debe ser apoyado por la evaluación permanente. La universidad como escenario legítimo de aprendizaje, producción y reconstrucción de conocimiento debe acompañar las transformaciones de la ciencia contemporánea y apoyar las exigencias interdisciplinarias en la construcción de nuevo conocimiento. Conclusión. Es fundamental el papel de la universidad en acoger y acompañar al docente desde su vinculación; así mismo la universidad debe favorecer el crecimiento del profesor, no solo apoyando los desafíos de su actividad pedagógica, sino principalmente a través del respeto de su autonomía.Objetivo. Analisar o papel da instituição ao escolher, acolher e acompanhar ao professor universitário. Metodologia. Estudo qualitativo, cujo corpo de análise esteve composto por 32 participações num foro temático de um grupo de nove profissionais da área da saúde. Resultados. Depois da contratação do professor, é necessário acolhê-lo e acompanhá-lo. Os professores com maior tempo de instituição representam um papel importante na acolhida do novo colega. O processo de acompanhamento é uma oportunidade para mudanças e redefinição de regras, e deve ser apoiado pela avaliação permanente. A universidade como palco legítimo de aprendizagem, produção e reconstrução de conhecimento deve acompanhar as transformações da ciência contemporânea e

  4. 75 FR 12161 - Establishment of Class E Airspace; Marianna, AR

    Science.gov (United States)

    2010-03-15

    ...-1167; Airspace Docket No. 09-ASW-33] Establishment of Class E Airspace; Marianna, AR AGENCY: Federal... proposes to establish Class E airspace at Marianna/Lee County Airport-Steve Edwards Field, Marianna, AR, to... operations at Marianna/Lee County Airport-Steve Edwards Field, Marianna, AR. Controlled airspace is needed...

  5. Execução de túneis com recurso ao método cut anda cover

    OpenAIRE

    Oliveira, Pedro Gustavo da Costa de

    2012-01-01

    Neste trabalho apresenta-se uma abordagem sobre a conceção e execução de túneis que incide na metodologia de execução de galerias a céu aberto (mais conhecida pela designação utilizada na língua inglesa – cut and cover). Na primeira parte do trabalho é enquadrado o tema, introduzindo-se uma perspetiva sobre a sua evolução histórica, descrevem-se as principais metodologias adotadas na construção de túneis, afloram-se as vantagens e desvantagens de cada metodologia, abordam-se de forma sumár...

  6. Potential hydroxyl ultraviolet laser. [Ar-H/sub 2/O

    Energy Technology Data Exchange (ETDEWEB)

    Chen, C H; Payne, M G

    1976-09-01

    A strong emission band extending from 3060 to 3120 A was observed following proton beam excitation of an Ar--H/sub 2/O mixture. This emission band was assigned to the transition of OH(A/sup 2/Sigma/sup +/)/sub nu=o/ ..-->.. OH(X/sup 2/Pi)/sub nu=o/. At high argon partial pressure (> 200 torr), the precursor of this emission band is believed to be the argon excimer Ar/sup *//sub 2/(1/sub u/). The fluorescence efficiency of Ar--H/sub 2/O is estimated to be a factor of 4 times that of Ar--N/sub 2/. Development of a highly efficient, tunable uv laser by e-beam pumping is promising.

  7. A phase one AR/C system design

    Science.gov (United States)

    Kachmar, Peter M.; Polutchko, Robert J.; Matusky, Martin; Chu, William; Jackson, William; Montez, Moises

    1991-01-01

    The Phase One AR&C System Design integrates an evolutionary design based on the legacy of previous mission successes, flight tested components from manned Rendezvous and Proximity Operations (RPO) space programs, and additional AR&C components validated using proven methods. The Phase One system has a modular, open architecture with the standardized interfaces proposed for Space Station Freedom system architecture.

  8. The beta decay asymmetry parameter of 35Ar

    International Nuclear Information System (INIS)

    Garnett, J.D.

    1987-11-01

    The beta decay asymmetry parameter for 35 Ar = 35 Cl + e + + nu/sub e/ has been remeasured in order to resolve a long standing puzzle. Previous asymmetry measurements, when combined with the comparative half-life, yield a value for the vector coupling constant, G/sub v/, that is in serious disagreement with the accepted value. We produced polarized 35 Ar by a (p,n) reaction on 35 Cl using the polarized proton beam provided by Lawrence Berkeley Laboratory's 88-Inch Cyclotron. The polarization of the 35 Ar was determined by measuring the asymmetry of the positrons produced in 35 Ar decay to the first excited state in 35 Cl (branching ratio = 1.3%) in coincidence with a 1219.4 keV gamma ray. Our result, A 0 = 0.49 +- 0.10, combined with the comparative half-life yields a value for G/sub v/ in agreement with the accepted value

  9. Geochemistry and 40Ar/39Ar age of Early Carboniferous dolerite sills in the southern Baltic Sea

    Directory of Open Access Journals (Sweden)

    Gediminas Motuza

    2015-08-01

    Full Text Available The Early Carboniferous magmatic event in the southern Baltic Sea is manifested by dolerite intrusions. The presumable area in which the dolerite intrusions occur ranges from 30 to 60 km in east–west direction, and is about 100 km in north–south direction. The dolerites were sampled in well D1-1 and investigated by applying chemical analysis and 40Ar/39Ar step-heating dating. Dolerites are classified as alkali and sodic, characterized by high TiO2 (3.92, 3.99 wt% and P2O5 (1.67, 1.77 wt% and low MgO (4.89, 4.91 wt% concentrations, enriched in light rare earth elements, originated from an enriched mantle magma source and emplaced in a continental rift tectonic setting. The 351 ± 11 Ma 40Ar/39Ar plateau age for groundmass plagioclase indicates a considerable age gap with the 310–250 Ma magmatism in southern Scandinavia and northern Germany. The magmatic rocks in the Baltic Sedimentary Basin are coeval with alkaline intrusions of NE Poland. Both magmatic provinces lie in the northwestward prolongation of the Pripyat–Dnieper–Donetsk Rift (370–359 Ma and may constitute a later phase of magmatic activity of this propagating rift system.

  10. Ar-Ar Ages of Nakhlites Y000593, NWA998, and Nakhla and CRE Age of NWA998.

    Science.gov (United States)

    Garrison, D. H.; Bogard, D. D.

    2006-01-01

    The seven known Martian nakhlites are Nakhla, Lafayette, Governador Valadares, and four recent finds from hot and cold deserts: MIL03346 from the Transantarctic Mountains, a paired group from the Yamato Mountains (Y000593, Y000749, and Y000802; 1), and two from Morocco (NWA998 and NWA817; 2). Radiometric ages (Sm-Nd, Rb-Sr, U-Pb, and Ar-Ar) for the first three nakhlites, along with Chassigny, fall in the range of 1.19-1.37 Gyr and may suggest a common formation age (e.g., 3). These meteorites also show very similar cosmic-ray (space) exposure ages, which suggests a single ejection event from Mars (3). The ages for nakhlites are different from those of Martian shergottites, whose radiometric ages vary by nearly a factor of three (approximately 165-475 Myr) and whose space exposure ages vary over a factor of approximately 20 (3). Shergottite ages suggest that multiple locations on the Martian surface have been sampled, whereas nakhlite data imply that only one Mars surface location has been sampled. Because older Martian surfaces are expected to be more abundant, it seems surprising that all nakhlites would represent only one Martian impact event. To address this issue, we are measuring the Ar-39-Ar-40 ages of Y-000593, NWA-998, Nakhla, and MIL-03346, and the space (CRE) exposure age of NWA998.

  11. Ar-Ar Ages of Nakhlites Y000593, NWA998, and Nakhla and CRE Ages of NWA998

    Science.gov (United States)

    Garrison, D. H.; Bogard, D. D.

    2005-01-01

    The seven known Martian nakhlites are Nakhla, Lafayette, Governador Valadares, and four recent finds from hot and cold deserts: MIL03346 from the Transantarctic Mountains, a paired group from the Yamato Mountains (Y000593, Y000749, and Y000802, and two from Morocco (NWA998 and NWA817. Radiometric ages (Sm-Nd, Rb-Sr, U-Pb, and Ar-Ar) for the first three nakhlites, along with Chassigny, fall in the range of 1.19-1.37 Gyr and may suggest a common formation age. These meteorites also show very similar cosmic-ray (space) exposure ages, suggesting a single ejection event from Mars. The ages for nakhlites are different from those of Martian shergottites, whose radiometric ages vary by nearly a factor of three (approx. 165-475 Myr) and whose space exposure ages vary over a factor of approx. 20. Shergottite ages suggest that multiple locations on the Martian surface have been sampled, whereas nakhlite data imply sampling of only one Mars surface location. Because older Martian surfaces are expected to be more abundant, it seems surprising that all nakhlites would represent only one Martian impact event. To address this issue, we are measuring the (39)Ar-(40)Ar ages of Y-000593, NWA-998, Nakhla, and MIL-03346, and the space (CRE) exposure age of NWA998. Additional information is included in the original extended abstract.

  12. Timing and processes for exhumation of HP/LT rocks of the southern Brooks Range (AK): Insight from combined geochemistry and 40Ar/39Ar thermochronology of white mica

    Science.gov (United States)

    O'Brien, T.; Miller, E. L.; Grove, M. J.; Hayden, L. A.

    2015-12-01

    The obduction of an island arc onto the Arctic Alaska continental margin in the Jura-Cretaceous led to southward subduction of continental crust and high-pressure/low-temperature (HP/LT) epidote-blueschist facies metamorphism in the southern Brooks Range (BR). A regionally developed greenschist facies normal-sense shear zone system along the southern margin of the BR suggests that extensional faulting had an influential role in the exhumation of the metamorphic core. To better constrain the exhumation history of the metamorphic core of the BR, samples were collected from a N-S transect through the metamorphic core of the orogen. Electron microprobe (EMP) analyses of white micas reveal that they are composed of phengite (Si > 3.0 pfu) or a combination of phengite + paragonite. Si-content of phengites reveal a southward increase in Si from 3.1 to 3.4 pfu (corresponding to an increase in pressure). Si-contents in higher-P phengites are scattered, reflecting subsequent muscovite growth. The Si trend is matched by a southward increase in the 40Ar/39Ar total gas ages of white micas. Phengite from the north are characterized by younger ages (~115 Ma) and flatter 40Ar/39Ar spectra. Farther south, phengites and paragonites yield older 40Ar/39Ar ages. These samples yield convex, staircase 40Ar/39Ar spectra that initiate ~115-120 Ma and flatten-out ~130-138 Ma. Modeling using MacArgon proposes that an initial cooling of HP/LT metamorphism occurred ~130-138 Ma, recorded in the high-Si phengites and paragonites. Following initial cooling, modeling suggests HP/LT rocks stalled in the greenschist facies field before subsequent exhumation, resulting in the staircase 40Ar/39Ar spectra. Flatter 40Ar/39Ar spectra recorded by the northern samples and modeling of 40Ar/39Ar results from the southern samples suggest that these rocks from metamorphic core of the BR were exhumed to temperatures < 300°C by ~115 Ma.

  13. 75 FR 66300 - Amendment of Class E Airspace; Searcy, AR

    Science.gov (United States)

    2010-10-28

    ...-1182; Airspace Docket No. 09-ASW-37] Amendment of Class E Airspace; Searcy, AR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for Searcy, AR. Decommissioning of the Searcy non-directional beacon (NDB) at Searcy Municipal Airport, Searcy, AR, has made this...

  14. 75 FR 29654 - Amendment of Class E Airspace; Manila, AR

    Science.gov (United States)

    2010-05-27

    ...-1184; Airspace Docket No. 09-ASW-39] Amendment of Class E Airspace; Manila, AR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for Manila, AR. Decommissioning of the Manila non-directional beacon (NDB) at Manila Municipal Airport, Manila, AR has made this...

  15. Noninvasive Detection of AR-FL/AR-V7 as a Predictive Biomarker for Therapeutic Resistance in Men with Metastatic Castration-Resistant Prostate Cancer

    Science.gov (United States)

    2017-10-01

    acknowledged federal support) 5. Antonarakis ES, Armstrong AJ, Dehm SM, Luo J. Androgen receptor variant-driven prostate cancer : clinical implications...Resistant Prostate Cancer abstract Purpose A splice variant of the androgen receptor , AR-V7, confers resistance to AR-targeted therapies (ATTs) but not...androgen receptor ; AR-V7, androgen receptor splice variant 7; mCRPC, metastatic castration-resistant prostate cancer ; n/N, number of patients in that

  16. XRD-based 40Ar/39Ar age correction for fine-grained illite, with application to folded carbonates in the Monterrey Salient (northern Mexico)

    Science.gov (United States)

    Fitz-Díaz, Elisa; Hall, Chris M.; van der Pluijm, Ben A.

    2016-05-01

    Due to their minute size, 40Ar/39Ar analysis of illite faces significant analytical challenges, including mineral characterization and, especially, effects of grain size and crystallography on 39Ar recoil. Quantifying the effects of 39Ar recoil requires the use of sample vacuum encapsulation during irradiation, which permits the measurement of the fraction of recoiled 39Ar as well as the 39Ar and 40Ar∗ retained within illite crystals that are released during step heating. Total-Gas Ages (TGA) are calculated by using both recoiled and retained argon, which is functionally equivalent to K-Ar ages, while Retention Ages (RA) only involve retained Ar in the crystal. Natural applications have shown that TGA fits stratigraphic constraints of geological processes when the average illite crystallite thickness (ICT) is smaller than 10 nm, and that RA matches these constraints for ICTs larger than 50 nm. We propose a new age correction method that takes into account the average ICT and corresponding recoiled 39Ar for a sample, with X-ray Corrected Ages (XCA) lying between Total-Gas and Retention Ages depending on ICT. This correction is particularly useful in samples containing authigenic illite formed in the anchizone, with typical ICT values between 10 and 50 nm. In three samples containing authigenic illite from Cretaceous carbonates in the Monterrey Salient in northern Mexico, there is a range in TGAs among the different size-fractions of 46-49, 36-43 and 40-52 Ma, while RAs range from 54-64, 47-52 and 53-54 Ma, respectively. XCA calculations produce tighter age ranges for these samples of 52.5-56, 45.5-48.5 and 49-52.5 Ma, respectively. In an apparent age vs ICT or %2M 1illite plot, authigenic illite grains show a slope that is in general slightly positive for TGA, slightly negative for RA, but close to zero for XCA, with thinner crystallites showing more dispersion than thicker ones. In order to test if dispersion is due to a different formation history or the result

  17. The ChArMEx database

    Science.gov (United States)

    Ferré, Helene; Belmahfoud, Nizar; Boichard, Jean-Luc; Brissebrat, Guillaume; Descloitres, Jacques; Fleury, Laurence; Focsa, Loredana; Henriot, Nicolas; Mastrorillo, Laurence; Mière, Arnaud; Vermeulen, Anne

    2014-05-01

    The Chemistry-Aerosol Mediterranean Experiment (ChArMEx, http://charmex.lsce.ipsl.fr/) aims at a scientific assessment of the present and future state of the atmospheric environment in the Mediterranean Basin, and of its impacts on the regional climate, air quality, and marine biogeochemistry. The project includes long term monitoring of environmental parameters, intensive field campaigns, use of satellite data and modelling studies. Therefore ChARMEx scientists produce and need to access a wide diversity of data. In this context, the objective of the database task is to organize data management, distribution system and services, such as facilitating the exchange of information and stimulating the collaboration between researchers within the ChArMEx community, and beyond. The database relies on a strong collaboration between OMP and ICARE data centres and has been set up in the framework of the Mediterranean Integrated Studies at Regional And Locals Scales (MISTRALS) program data portal. All the data produced by or of interest for the ChArMEx community will be documented in the data catalogue and accessible through the database website: http://mistrals.sedoo.fr/ChArMEx. At present, the ChArMEx database contains about 75 datasets, including 50 in situ datasets (2012 and 2013 campaigns, Ersa background monitoring station), 25 model outputs (dust model intercomparison, MEDCORDEX scenarios), and a high resolution emission inventory over the Mediterranean. Many in situ datasets have been inserted in a relational database, in order to enable more accurate data selection and download of different datasets in a shared format. The database website offers different tools: - A registration procedure which enables any scientist to accept the data policy and apply for a user database account. - A data catalogue that complies with metadata international standards (ISO 19115-19139; INSPIRE European Directive; Global Change Master Directory Thesaurus). - Metadata forms to document

  18. 40Ar-39Ar laser probe dating of individual clinopyroxene inclusions in Premier eclogitic diamonds

    International Nuclear Information System (INIS)

    Burgess, R.; Turner, G.; Laurenzi, M.; Harris, J.W.

    1989-01-01

    The ages of seven individual clinopyroxene inclusions in Premier diamonds of eclogitic association have been determined using the 40 Ar- 39 Ar dating technique. Syngenetic inclusions weighing between 10 and 130 μg were exposed on cleaved surfaces of the diamonds and analysed using a laser probe. The inclusion ages were found to be in the range 1111±35 to 1254±38 Ma with an average of 1185±94 Ma. The ages obtained are in good agreement with previous determinations made on aggregates of eclogitic inclusions from Premier diamonds and demonstrate the applicability of the laser probe to dating individual diamond inclusions. (orig.)

  19. Piesaistes stila saistība ar apmierinātību ar dzīvi

    OpenAIRE

    Čiekure, Līva

    2015-01-01

    Pētījuma mērķis ir noskaidrot vai pastāv saistības starp piesaistes stilu un apmierinātību ar dzīvi. Tika aptaujāti 100 respondenti- 50 sievietes un 50 vīrieši. Pētījumā tika izmantotas Piesaistes stilu aptauja (Attachment Styles -Inventory /ASI/, Sperling & Berman, 1991), Latvijā adaptējusi Baiba Martinsone (2003) un Apmierinātības ar dzīvi aptauja ( Satisfaction with life scales,/SWLS/, Diener, 1985), Latvijā adaptēja Maslovska, Voitkāne, Miezīte & Raščevska ( 2005) un Upmane (Upmane, 2010)...

  20. CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells.

    Science.gov (United States)

    Ito, Saya; Ueno, Akihisa; Ueda, Takashi; Nakagawa, Hideo; Taniguchi, Hidefumi; Kayukawa, Naruhiro; Fujihara-Iwata, Atsuko; Hongo, Fumiya; Okihara, Koji; Ukimura, Osamu

    2018-04-03

    The androgen receptor (AR) is a ligand-dependent transcription factor that promotes prostate cancer (PC) cell growth through control of target gene expression. This report suggests that Canopy FGF signaling regulator 2 (CNPY2) controls AR protein levels in PC cells. We found that AR was ubiquitinated by an E3 ubiquitin ligase, myosin regulatory light chain interacting protein (MYLIP) and then degraded through the ubiquitin-proteasome pathway. CNPY2 decreased the ubiquitination activity of MYLIP by inhibition of interaction between MYLIP and UBE2D1, an E2 ubiquitin ligase. CNPY2 up-regulated gene expression of AR target genes such as KLK3 gene which encodes the prostate specific antigen (PSA) and promoted cell growth of PC cells. The cell growth inhibition by CNPY2 knockdown was rescued by AR overexpression. Furthermore, positive correlation of expression levels between CNPY2 and AR/AR target genes was observed in tissue samples from human prostate cancer patients. Together, these results suggested that CNPY2 promoted cell growth of PC cells by inhibition of AR protein degradation through MYLIP-mediated AR ubiquitination.

  1. 40Ar/39Ar dates in the Central Cordillera of Colombia: Evidence for an upper triassic regional tecnomagmatic event

    International Nuclear Information System (INIS)

    Vinasco, C.J.; Cordani, U.G.; Vasconcelos, P

    2001-01-01

    The Coastal, Western, Central and the Eastern Cordilleras constitute four independent mountain ranges in the Northern Andes. The Coastal and Western Cordillera comprises allochthonous oceanic sequences of basic volcanic rocks and marine sediments of Cenozoic and Upper Cretaceous age (Aspden et al., 1987). The so-called Central Cordillera Polymetamorphic Complex (Restrepo and Toussaint, 1982), made up the pre-Mesozoic Central Cordillera basement, consists of low through high-grade metamorphic rocks intruded by Meso-Cenozoic batholiths. The Eastern Cordillera is a polydeformed continental mountain range consisting of Precambrian and Paleozoic metamorphic and igneous rocks overlain by Paleozoic to Mesozoic sedimentary covers. The northern part of the Central Cordillera has been described as a suspect terrain affected by several tectonometamorphic episodes. The most important of them have been always considered those related to the Hercynian orogeny, in Devonian and Carboniferous times, and those occurring at the beginning of the Andean Cycle in the Cretaceous (Restrepo and Toussaint, 1982). A possible Lower Paleozoic and even Precambrian age for the basement of the terrain has also been proposed. Although some indications of a Permo-Triassic event are already available, this period was not considered as of great importance for the geologic evolution of the region. The available radiometric dates in the 200-250 Ma interval, for the Central Cordillera, are as follows: 1. One K-Ar whole rock age for a Granulite of 251±21 Ma. (Restrepo et al, 1991) of the El Retiro group SE of Medellin. However, a K-Ar biotite age of 110±10 Ma. (Toussaint et al., 1978) was obtained for a migmatite rock associated with the same group. 2. A Sm/Nd garnet and whole rock age of 226±17 Ma in rocks associated to granulites, SE of Medellin, interpreted as metamorphic ages (Correa and Martins, 2001). 3. K-Ar biotite dates for the Puqui metamorphic complex, occurring north of Medellin, ranging

  2. Suppression of Plant Immune Responses by the Pseudomonas savastanoi pv. savastanoi NCPPB 3335 Type III Effector Tyrosine Phosphatases HopAO1 and HopAO2

    Directory of Open Access Journals (Sweden)

    María Pilar Castañeda-Ojeda

    2017-05-01

    Full Text Available The effector repertoire of the olive pathogen P. savastanoi pv. savastanoi NCPPB 3335 includes two members of the HopAO effector family, one of the most diverse T3E families of the P. syringae complex. The study described here explores the phylogeny of these dissimilar members, HopAO1 and HopAO2, among the complex and reveals their activities as immune defense suppressors. Although HopAO1 is predominantly encoded by phylogroup 3 strains isolated from woody organs of woody hosts, both HopAO1 and HopAO2 are phylogenetically clustered according to the woody/herbaceous nature of their host of isolation, suggesting host specialization of the HopAO family across the P. syringae complex. HopAO1 and HopAO2 translocate into plant cells and show hrpL-dependent expression, which allows their classification as actively deployed type III effectors. Our data also show that HopAO1 and HopAO2 possess phosphatase activity, a hallmark of the members of this family. Both of them exert an inhibitory effect on early plant defense responses, such as ROS production and callose deposition, and are able to suppress ETI responses induced by the effectorless polymutant of P. syringae pv. tomato DC3000 (DC3000D28E in Nicotiana. Moreover, we demonstrate that a ΔhopAO1 mutant of P. savastanoi NCPBB 3335 exhibits a reduced fitness and virulence in olive plants, which supports the relevance of this effector during the interaction of this strain with its host plants. This work contributes to the field with the first report regarding functional analysis of HopAO homologs encoded by P. syringae or P. savastanoi strains isolated from woody hosts.

  3. Suppression of Plant Immune Responses by the Pseudomonas savastanoi pv. savastanoi NCPPB 3335 Type III Effector Tyrosine Phosphatases HopAO1 and HopAO2

    Science.gov (United States)

    Castañeda-Ojeda, María Pilar; Moreno-Pérez, Alba; Ramos, Cayo; López-Solanilla, Emilia

    2017-01-01

    The effector repertoire of the olive pathogen P. savastanoi pv. savastanoi NCPPB 3335 includes two members of the HopAO effector family, one of the most diverse T3E families of the P. syringae complex. The study described here explores the phylogeny of these dissimilar members, HopAO1 and HopAO2, among the complex and reveals their activities as immune defense suppressors. Although HopAO1 is predominantly encoded by phylogroup 3 strains isolated from woody organs of woody hosts, both HopAO1 and HopAO2 are phylogenetically clustered according to the woody/herbaceous nature of their host of isolation, suggesting host specialization of the HopAO family across the P. syringae complex. HopAO1 and HopAO2 translocate into plant cells and show hrpL-dependent expression, which allows their classification as actively deployed type III effectors. Our data also show that HopAO1 and HopAO2 possess phosphatase activity, a hallmark of the members of this family. Both of them exert an inhibitory effect on early plant defense responses, such as ROS production and callose deposition, and are able to suppress ETI responses induced by the effectorless polymutant of P. syringae pv. tomato DC3000 (DC3000D28E) in Nicotiana. Moreover, we demonstrate that a ΔhopAO1 mutant of P. savastanoi NCPBB 3335 exhibits a reduced fitness and virulence in olive plants, which supports the relevance of this effector during the interaction of this strain with its host plants. This work contributes to the field with the first report regarding functional analysis of HopAO homologs encoded by P. syringae or P. savastanoi strains isolated from woody hosts. PMID:28529516

  4. Atividade colinesterásica cerebral e comportamento de ratos após exposição perinatal ao diclorvós Brain cholinesterase activity and the behavior of rats after perinatal exposure to dichlorvos

    Directory of Open Access Journals (Sweden)

    Jaqueline Pérola de Souza

    2006-04-01

    Full Text Available O organofosforado diclorvós impregnado em coleiras plásticas é um recurso utilizado em medicina veterinária que visa ao controle de ectoparasitas de cães e gatos. O objetivo deste trabalho foi avaliar os efeitos do uso de coleiras plásticas impregnadas com diclorvós (8,37% em ratas Wistar durante o período de gestação e lactação, como possível fonte de alterações comportamentais e da atividade colinesterásica cerebral dos filhotes. Na desmama, não houve diferença na atividade colinesterásica cerebral entre as mães tratadas com diclorvós e o grupo controle, bem como entre os respectivos filhotes. O tratamento com diclorvós também não influenciou no comportamento geral dos animais, avaliado no campo aberto, nem no nível de ansiedade testado no labirinto em cruz elevado, ambos aos 35 dias pós-natal.The organophosphate dichlorvos impregnated into plastic collars (8.37% is used in veterinary practice as an alternative for the control of ectoparasites in dogs and cats. The aim of this work was to determine the possible toxic effects of these collars in female Wistar rats during pregnancy and lactation, as a possible cause of alterations in brain cholinesterase activity and behavior of offspring. At weaning, there was no difference in brain cholinesterase activity between control and treated dams, nor between their respective offspring as well. The treatment did not affect the general behavior of the offspring, when evaluated in the open field, nor anxiety in the elevated plus-maze, both evaluated on the 35th postnatal day.

  5. A high-precision 40Ar/39Ar age for the Nördlinger Ries impact crater, Germany, and implications for the accurate dating of terrestrial impact events

    Science.gov (United States)

    Schmieder, Martin; Kennedy, Trudi; Jourdan, Fred; Buchner, Elmar; Reimold, Wolf Uwe

    2018-01-01

    40Ar/39Ar dating of specimens of moldavite, the formation of which is linked to the Ries impact in southern Germany, with a latest-generation ARGUS VI multi-collector mass spectrometer yielded three fully concordant plateau ages with a weighted mean age of 14.808 ± 0.021 Ma (± 0.038 Ma including all external uncertainties; 2σ; MSWD = 0.40, P = 0.67). This new best-estimate age for the Nördlinger Ries is in general agreement with previous 40Ar/39Ar results for moldavites, but constitutes a significantly improved precision with respect to the formation age of the distal Ries-produced tektites. Separates of impact glass from proximal Ries ejecta (suevite glass from three different surface outcrops) and partially melted feldspar particles from impact melt rock of the SUBO 18 Enkingen drill core failed to produce meaningful ages. These glasses show evidence for excess 40Ar introduction, which may have been incurred during interaction with hydrothermal fluids. Only partially reset 40Ar/39Ar ages could be determined for the feldspathic melt separates from the Enkingen core. The new 40Ar/39Ar results for the Ries impact structure constrain the duration of crater cooling, during the prevailing hydrothermal activity, to locally at least ∼60 kyr. With respect to the dating of terrestrial impact events, this paper briefly discusses a number of potential issues and effects that may be the cause for seemingly precise, but on a kyr-scale inaccurate, impact ages.

  6. 40Ar/ 39Ar and paleomagnetic results from Liberia and the Precambrian APW data base for the West African Shield

    Science.gov (United States)

    Onstott, T. C.; Dorbor, J.

    Lower amphibolite to granulite facies metamorphic rocks in Nimba County, Liberia have yielded 2.2-2.9 Ga RbSr whole rock ages, indicating that they are part of the Archean Liberian age province. We report a 2040 Ma 4040Ar/ 39Ar plateau date on hornblende from an amphibolite in this region, and suggest that these rocks were also severelyreworked during the Eburnean (˜2.0 Ga) metamorphic episode. 40Ar/ 39Ar analyses of biotite and feldspars from neighboring schists also indicate the presence of two mild thermal events, at 1.5 Ga and 0.6 Ga. Paleomagnetic analyses of samples from these same metamorphic rocks reveal three components of magnetization. The predominant and most stable component (273°E, 21°N) is considered to have been acquired as a result of pos Eburnean uplift and cooling at ˜ 2.0 Ga, whereas the two less stable components with poles at 235°E, 43°N and 16°E, 36°N, probably correlate with the 1.5 Ga and 0.6 Ga thermal pulses, respectively. Rock units from southern Liberia also yield two secondary magnetizations, one at 247°E, 37°N and the other at 104°E, 5°N, and a 1.5 Ga 40Ar/ 39Ar date on plagioclase. Comparison of the paleomagnetic poles corresponding to the ˜2.0 Ga Eburnean component with published paleomagnetic data for West Africa is not consistent with prior interpretations of the polar wander path for West Africa. Our paleomagnetic data, when compared to poles of comparable age from the Kalahari Shield, still suggest that some form of displacement has occurred between the Kalahari and West African Shields since 2.0 Ga.

  7. Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer.

    Science.gov (United States)

    Khurana, Namrata; Kim, Hogyoung; Chandra, Partha K; Talwar, Sudha; Sharma, Pankaj; Abdel-Mageed, Asim B; Sikka, Suresh C; Mondal, Debasis

    2017-11-01

    Prostate cancer (PCa) cells expressing full-length androgen receptor (AR-FL) are susceptible to androgen deprivation therapy (ADT). However, outgrowth of castration-resistant prostate cancer (CRPC) can occur due to the expression of constitutively active (ligand-independent) AR splice variants, particularly AR-V7. We previously demonstrated that sulforaphane (SFN), an isothiocyanate phytochemical, can decrease AR-FL levels in the PCa cell lines, LNCaP and C4-2B. Here, we examined the efficacy of SFN in targeting both AR-FL and AR-V7 in the CRPC cell line, CWR22Rv1 (22Rv1). MTT cell viability, wound-heal assay, and colony forming unit (CFU) measurements revealed that 22Rv1 cells are resistant to the anti-androgen, enzalutamide (ENZ). However, co-exposure to SFN sensitized these cells to the potent anticancer effects of ENZ (PAR-FL and AR-V7 levels, and immunofluorescence microscopy (IFM) depicted decreased AR in both cytoplasm and nucleus with SFN treatment. SFN increased both ubiquitination and proteasomal activity in 22Rv1 cells. Studies using a protein synthesis inhibitor (cycloheximide) or a proteasomal inhibitor (MG132) indicated that SFN increases both ubiquitin-mediated aggregation and subsequent proteasomal-degradation of AR proteins. Previous studies reported that SFN inhibits the chaperone activity of heat-shock protein 90 (Hsp90) and induces the nuclear factor erythroid-2-like 2 (Nrf2) transcription factor. Therefore, we investigated whether the Hsp90 inhibitor, ganetespib (G) or the Nrf2 activator, bardoxolone methyl (BM) can similarly suppress AR levels in 22Rv1 cells. Low doses of G and BM, alone or in combination, decreased both AR-FL and AR-V7 levels, and combined exposure to G+BM sensitized 22Rv1 cells to ENZ. Therefore, adjunct treatment with the phytochemical SFN or a safe pharmaceutical combination of G+BM may be effective against CRPC cells, especially those expressing AR-V7.

  8. Hybrid simulation of electron energy distributions and plasma characteristics in pulsed RF CCP sustained in Ar and SiH4/Ar discharges

    Science.gov (United States)

    Wang, Xi-Feng; Jia, Wen-Zhu; Song, Yuan-Hong; Zhang, Ying-Ying; Dai, Zhong-Ling; Wang, You-Nian

    2017-11-01

    Pulsed-discharge plasmas offer great advantages in deposition of silicon-based films due to the fact that they can suppress cluster agglomeration, moderate the energy of bombarding ions, and prolong the species' diffusion time on the substrate. In this work, a one-dimensional fluid/Monte-Carlo hybrid model is applied to study pulse modulated radio-frequency (RF) plasmas sustained in capacitively coupled Ar and SiH4/Ar discharges. First, the electron energy distributions in pulsed Ar and SiH4/Ar plasmas have been investigated and compared under identical discharge-circuit conditions. The electron energy distribution function (EEDF) in Ar discharge exhibits a familiar bi-Maxwellian shape during the power-on phase of the pulse, while a more complex (resembling a multi-Maxwellian) distribution with extra inflection points at lower energies is observed in the case of the SiH4/Ar mixture. These features become more prominent with the increasing fraction of SiH4 in the gas mixture. The difference in the shape of the EEDF (which is pronounced inside the plasma but not in the RF sheath where electron heating occurs) is mainly attributed to the electron-impact excitations of SiH4. During the power-off phase of the pulse, the EEDFs in both Ar and SiH4/Ar discharges evolve into bi-Maxwellian shapes, with shrinking high energy tails. Furthermore, the parameter of ion species in the case of SiH4/Ar discharge is strongly modulated by pulsing. For positive ions, such as SiH3+ and Si2H4+ , the particle fluxes overshoot at the beginning of the power-on interval. Meanwhile, for negative ions such as SiH2- and SiH3- , density profiles observed between the electrodes are saddle-shaped due to the repulsion by the self-bias electric field as it builds up. During the power-off phase, the wall fluxes of SiH2- and SiH3- gradually increase, leading to a significant decrease in the net surface charge density on the driven electrode. Compared with ions, the density of SiH3 is poorly modulated

  9. 40Ar/(39)Ar geochronology and paleomagnetic stratigraphy of the Lukeino and lower Chemeron Formations at Tabarin and Kapcheberek, Tugen Hills, Kenya.

    Science.gov (United States)

    Deino, Alan L; Tauxe, Lisa; Monaghan, Marc; Hill, Andrew

    2002-01-01

    (40)Ar/(39)Ar single-crystal laser-fusion dating, K-Ar dating, and paleomagnetic reversal stratigraphy have been used to determine the chronostratigraphy of the Kabarnet Trachyte, Lukeino Formation, Kaparaina Basalt Formation, and Chemeron Formation at the sites of Kapcheberek (BPRP#77) and Tabarin (BPRP#77) in the Tugen Hills, Kenya. The succession ranges in age from 6.56-3.8 Ma. The upper Lukeino Formation at Kapcherberek, including the fauna from the site BPRP#76, was deposited during chron C3r and can be constrained to the interval 5.88-5.72 Ma. The Chemeron Formation at Tabarin includes at the base an ignimbrite and associated basal air-fall tuff with a combined age of 5.31+/-0.03 Ma. Sedimentary and volcaniclastic rocks of the Chemeron Formation which unconformably overlie the ignimbrite record chrons C3n.2n through C2Ar. The combined(40)Ar/(39)Ar and paleomagnetic data constrain the age of this sequence to 4.63-3.837 Ma. The age of the Tabarin mandible fragment (KNM-TH 13150) and associated fauna at site BPRP#77 in the Chemeron Formation is 4.48-4.41 Ma, marginally older than similar early hominids from Aramis, Ethiopia. Basin subsidence appears to be defining an overall accumulation rate of about 17 cm/ka over the 2.7 Ma represented at Tabarin and Kapcheberek, despite episodes of rapid accumulation and hiatuses. Copyright 2002 Academic Press.

  10. Evidências sobre as estruturas de propriedade de capital e de voto das empresas de capital aberto no Brasil

    Directory of Open Access Journals (Sweden)

    Dante Mendes Aldrighi

    2007-06-01

    Full Text Available Este artigo analisa a evolução da estrutura de propriedade de capital e de votos das empresas de capital aberto no Brasil no período 1997-2002. Sua principal contribuição reside em estimar a magnitude dos direitos de voto e de fluxo de caixa do acionista último com a maior parcela do capital votante de cada empresa. Examinam-se, também, as fontes da discrepância entre direitos de votos e de fluxo de caixa, avaliando-se a importância relativa da emissão de ações preferenciais sem direito a voto, acordos de votos, estruturas piramidais de propriedade, e posse cruzada de ações. A base de dados compreende 4478 relatórios que as empresas, cumprindo uma exigência legal, submeteram à CVM nesse período.This paper focuses on the ownership and voting structures of limited liability companies in Brazil over the period 1997-2002. Its main contribution lies in measuring the magnitude of deviations between control rights and cash-flow rights for the ultimate shareholder with the largest voting rights. Furthermore, it pinpoints how these discrepancies are generated, evaluating the relative importance of the issuance of preferred stocks with no voting rights, voting agreements, pyramidal arrangements of ownership, and cross-shareholdings. The data set embraces 4,478 reports that companies, complying with a mandatory requirement, filed to the CVM over that period.

  11. Robo-AO KP: A new era in robotic adaptive optics

    Science.gov (United States)

    Riddle, Reed L.; Baranec, Christoph; Law, Nicholas M.; Kulkarni, Shrinivas R.; Duev, Dmitry; Ziegler, Carl; Jensen-Clem, Rebecca M.; Atkinson, Dani Eleanor; Tanner, Angelle M.; Zhang, Celia; Ray, Amy

    2016-01-01

    Robo-AO is the first and only fully automated adaptive optics laser guide star AO instrument. It was developed as an instrument for 1-3m robotic telescopes, in order to take advantage of their availability to pursue large survey programs and target of opportunity observations that aren't possible with other AO systems. Robo-AO is currently the most efficient AO system in existence, and it can achieve an observation rate of 20+ science targets per hour. In more than three years of operations at Palomar Observatory, it has been quite successful, producing technology that is being adapted by other AO systems and robotic telescope projects, as well as several high impact scientific publications. Now, Robo-AO has been selected to take over operation of the Kitt Peak National Observatory 2.1m telescope. This will give Robo-AO KP the opportunity to pursue multiple science programs consisting of several thousand targets each during the three years it will be on the telescope. One-sixth of the observing time will be allocated to the US community through the NOAO TAC process. This presentation will discuss the process adapting Robo-AO to the KPNO 2.1m telescope, the plans for integration and initial operations, and the science operations and programs to be pursued.

  12. NEW ACCURATE MEASUREMENT OF {sup 36}ArH{sup +} AND {sup 38}ArH{sup +} RO-VIBRATIONAL TRANSITIONS BY HIGH RESOLUTION IR ABSORPTION SPECTROSCOPY

    Energy Technology Data Exchange (ETDEWEB)

    Cueto, M.; Herrero, V. J.; Tanarro, I.; Doménech, J. L. [Molecular Physics Department, Instituto de Estructura de la Materia (IEM-CSIC), Serrano 123, E-28006 Madrid (Spain); Cernicharo, J. [Department of Astrophysics, CAB. INTA-CSIC. Crta Torrejón-Ajalvir Km 4, E-28850 Torrejón de Ardoz, Madrid (Spain); Barlow, M. J.; Swinyard, B. M., E-mail: jl.domenech@csic.es [Department of Physics and Astronomy, University College London. Gower Street, London WC1E 6BT (United Kingdom)

    2014-03-01

    The protonated argon ion, {sup 36}ArH{sup +}, was recently identified in the Crab Nebula from Herschel spectra. Given the atmospheric opacity at the frequency of its J = 1-0 and J = 2-1 rotational transitions (617.5 and 1234.6 GHz, respectively), and the current lack of appropriate space observatories after the recent end of the Herschel mission, future studies on this molecule will rely on mid-infrared observations. We report on accurate wavenumber measurements of {sup 36}ArH{sup +} and {sup 38}ArH{sup +} rotation-vibration transitions in the v = 1-0 band in the range 4.1-3.7 μm (2450-2715 cm{sup –1}). The wavenumbers of the R(0) transitions of the v = 1-0 band are 2612.50135 ± 0.00033 and 2610.70177 ± 0.00042 cm{sup –1} (±3σ) for {sup 36}ArH{sup +} and {sup 38}ArH{sup +}, respectively. The calculated opacity for a gas thermalized at a temperature of 100 K and with a linewidth of 1 km s{sup –1} of the R(0) line is 1.6 × 10{sup –15} × N({sup 36}ArH{sup +}). For column densities of {sup 36}ArH{sup +} larger than 1 × 10{sup 13} cm{sup –2}, significant absorption by the R(0) line can be expected against bright mid-IR sources.

  13. Adesão ao tratamento da ambliopia

    Directory of Open Access Journals (Sweden)

    Arakaki Mara Regina

    2004-01-01

    Full Text Available OBJETIVO: Avaliar a influência da adesão no resultado do tratamento da ambliopia. MÉTODOS: Foi feito estudo retrospectivo avaliando a resposta ao tratamento da ambliopia em 151 crianças portadoras de ambliopia, tratadas com esquema de oclusão diária, com o número de dias variando de acordo com a idade da criança. Os pacientes foram separados em dois grupos que diferiam entre si pela adesão ou não ao tratamento. RESULTADOS: Observou-se que o tratamento teve melhores resultados nas crianças de 4 a 7 anos e que aderiram ao tratamento; as crianças que aderiram ao tratamento necessitaram de tempo menor de permanência em tratamento. Mesmo crianças com idade superior a 7 anos tiveram resultados positivos com a oclusão. CONCLUSÃO:O tratamento oclusivo é um meio terapêutico eficiente desde que haja a cooperação do paciente.

  14. Tamanho ao nascer e problemas de saúde mental aos 11 anos em uma coorte brasileira de nascimentos

    Directory of Open Access Journals (Sweden)

    Erika Alejandra Giraldo Gallo

    2011-08-01

    Full Text Available O objetivo foi avaliar a associação entre tamanho ao nascer e problemas de saúde mental aos 11 anos na Coorte de Nascimentos de Pelotas, Rio Grande do Sul, Brasil, de 1993. Foram pesados e medidos ao nascer 4.358 recém-nascidos. Avaliou-se problemas de saúde mental com o questionário de capacidades e dificuldades (Strengths and Difficulties Questionnaire - SDQ. A prevalência de problemas de saúde mental foi de 32% (IC95%: 31-33. Na análise ajustada, os 291 (6,7% recém-nascidos com escorez de peso/idade e os 268 (6,2% com índice de massa corporal (IMC/idade +2 DP tiveram, respectivamente, 34% (IC95%: 6-71 e 19% (IC95%: 1-40 maior risco de apresentar esses problemas se comparados com aqueles com escore normal. Os resultados sugerem que fatores ocorridos na gestação e refletidos nas medidas de tamanho ao nascer podem ocasionar problemas de saúde mental em etapas tardias.

  15. Beam-induced back-streaming electron suppression analysis for an accelerator type neutron generator designed for 40Ar/39Ar geochronology.

    Science.gov (United States)

    Waltz, Cory; Ayllon, Mauricio; Becker, Tim; Bernstein, Lee; Leung, Ka-Ngo; Kirsch, Leo; Renne, Paul; Bibber, Karl Van

    2017-07-01

    A facility based on a next-generation, high-flux D-D neutron generator has been commissioned and it is now operational at the University of California, Berkeley. The current generator designed for 40 Ar/ 39 Ar dating of geological materials produces nearly monoenergetic 2.45MeV neutrons at outputs of 10 8 n/s. The narrow energy range is advantageous relative to the 235 U fission spectrum neutrons due to (i) reduced 39 Ar recoil energy, (ii) minimized production of interfering argon isotopes from K, Ca, and Cl, and (iii) reduced total activity for radiological safety and waste generation. Calculations provided show that future conditioning at higher currents and voltages will allow for a neutron output of over 10 10 n/s, which is a necessary requirement for production of measurable quantities of 39 Ar through the reaction 39 K(n,p) 39 Ar. A significant problem encountered with increasing deuteron current was beam-induced electron backstreaming. Two methods of suppressing secondary electrons resulting from the deuterium beam striking the target were tested: the application of static electric and magnetic fields. Computational simulations of both techniques were done using a finite element analysis in COMSOL Multiphysics ® . Experimental tests verified these simulations. The most reliable suppression was achieved via the implementation of an electrostatic shroud with a voltage offset of -800V relative to the target. Copyright © 2017. Published by Elsevier Ltd.

  16. ANÁLISE DOS PARÂMETROS DE FUNCIONAMENTO E SIMULAÇÃO COMPUTACIONAL EM UM PROTÓTIPO DE TURBINA OPERANDO A AR COMPRIMIDO

    Directory of Open Access Journals (Sweden)

    Wesley Saldanha Nogueira Oliveira

    2016-12-01

    Full Text Available RESUMO. Este trabalho apresenta os resultados iniciais da comparação de alguns parâmetros de funcionamento do protótipo de uma turbina de ação simples, operando com ar comprimido como fluido de trabalho, realizados na unidade do SENAI de Barra do Piraí/RJ. O protótipo foi desenvolvido integralmente no Centro Universitário Geraldo Di Biase - UGB - Campus de Barra do Piraí/RJ, que inicialmente teve como o fluido de trabalho o vapor d’água, que nos testes inicias se mostrou ineficiente. A simulação computacional do sistema foi feita através do software SolidWorks na Universidade Federal Fluminense - UFF - Campus de Volta Redonda/RJ, o que permitiu determinar a faixa de trabalho que apresentou maior eficiência nos resultados experimentais do sistema por meio da relação entre pressão de operação, velocidade angular transmitida pelo fluido ao eixo da turbina e a potência da mesma. Os valores nas simulações em velocidade tangencial na região rotacional apresentaram-se convergentes aos valores experimentais medidos no protótipo.

  17. Measurements of the {sup 40}Ar(n, γ){sup 41}Ar radiative-capture cross section between 0.4 and 14.8 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Bhike, Megha, E-mail: megha@tunl.duke.edu [Department of Physics, Duke University, Durham, NC 27708 (United States); Triangle Universities Nuclear Laboratory, Durham, NC 27708 (United States); Fallin, B.; Tornow, W. [Department of Physics, Duke University, Durham, NC 27708 (United States); Triangle Universities Nuclear Laboratory, Durham, NC 27708 (United States)

    2014-09-07

    The {sup 40}Ar(n, γ){sup 41}Ar neutron capture cross section has been measured between 0.4 and 14.8 MeV neutron energy using the activation technique. The data are important for estimating backgrounds in argon-based neutrino and dark-matter detectors and in the neutrino-less double-beta decay search GERDA, which uses liquid argon as cooling and shielding medium. For the first time the {sup 40}Ar(n, γ){sup 41}Ar cross section has been measured for neutron energies above 1 MeV. Our results are compared to the evaluation ENDF/B-VII.1 and the calculated prediction TENDL-2013. The latter agrees very well with the present results.

  18. 75 FR 53876 - Proposed Establishment of Class E Airspace; Berryville, AR

    Science.gov (United States)

    2010-09-02

    ... Class E Airspace; Berryville, AR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This action proposes to establish Class E airspace at Berryville, AR... SIAPs operations at Carroll County Airport, Berryville, AR. Controlled airspace is needed for the safety...

  19. 78 FR 25231 - Proposed Establishment of Class E Airspace; Colt, AR

    Science.gov (United States)

    2013-04-30

    ...-1281; Airspace Docket No. 12-ASW-13] Proposed Establishment of Class E Airspace; Colt, AR AGENCY... action proposes to establish Class E airspace at Colt, AR. Controlled airspace is necessary to...-mile radius of Delta Regional Airport, Colt, AR, to accommodate new standard instrument approach...

  20. Cerebral A1 adenosine receptors (A1AR) in liver cirrhosis

    International Nuclear Information System (INIS)

    Boy, Christian; Meyer, Philipp T.; Kircheis, Gerald; Haussinger, Dieter; Holschbach, Marcus H.; Coenen, Heinz H.; Herzog, Hans; Elmenhorst, David; Kaiser, Hans J.; Zilles, Karl; Bauer, Andreas

    2008-01-01

    The cerebral mechanisms underlying hepatic encephalopathy (HE) are poorly understood. Adenosine, a neuromodulator that pre- and postsynaptically modulates neuronal excitability and release of classical neurotransmitters via A 1 adenosine receptors (A 1 AR), is likely to be involved. The present study investigates changes of cerebral A 1 AR binding in cirrhotic patients by means of positron emission tomography (PET) and [ 18 F]CPFPX, a novel selective A 1 AR antagonist. PET was performed in cirrhotic patients (n = 10) and healthy volunteers (n = 10). Quantification of in vivo receptor density was done by Logan's non-invasive graphical analysis (pons as reference region). The outcome parameter was the apparent binding potential (aBP, proportional to B max /K D ). Cortical and subcortical regions showed lower A 1 AR binding in cirrhotic patients than in controls. The aBP changes reached statistical significance vs healthy controls (p 1 AR binding may further aggravate neurotransmitter imbalance at the synaptic cleft in cirrhosis and hepatic encephalopathy. Different pathomechanisms may account for these alterations including decrease of A 1 AR density or affinity, as well as blockade of the A 1 AR by endogenous adenosine or exogenous xanthines. (orig.)

  1. INFLUÊNCIA DE DIFERENTES TIPOS DE EMBALAGENS NAS CARACTERÍSTICAS FÍSICO-QUÍMICAS E COMPOSIÇÃO GASOSA DE BRÓCOLIS (Brassica oleracea L. var Itálica ORGÂNICOS MINIMAMENTE PROCESSADOS E ARMAZENADOS SOB REFRIGERAÇÃO

    Directory of Open Access Journals (Sweden)

    M. L. PADULA

    2009-01-01

    Full Text Available

    Este trabalho teve como objetivo avaliar os efeitos dos diferentes tipos de embalagens na vida útil de brócolis (Brassica oleracea orgânicos minimamente processados e armazenados sob refrigeração. As amostras foram selecionadas e higienizadas, centrifugadas e acondicionados em embalagens de polipropileno (PP, câmara de acrílico hermeticamente selada e com canais abertos à 10ºC por doze dias. Para avaliar a vida útil do produto foram realizadas análises físico-químicas a cada três dias e de composição gasosa, em função de O2 e CO2, diariamente durante dez dias, por cromatografia gasosa. Os resultados mostraram que a umidade das amostras não foi afetada significativamente pelo período de armazenamento. O pH, acidez total titulável e o conteúdo de sólidos solúveis aumentaram ao longo do período de armazenamento. A perda de massa durante o armazenamento foi inferior a 1% em todas as amostras analisadas. A embalagem que melhor preservou a textura dos brócolis ao longo do período de armazenamento foi a de acrílico selado. A degradação das clorofilas a e b, e a síntese de carotenóides foram mais acentuadas nas flores das amostras acondicionadas em acrílico com canais abertos. A composição gasosa apresentou comportamento similar ao observado na literatura. Os dados experimentais de concentração apresentaram bom ajuste aos dados da literatura.

  2. Decisive factors affecting plasma resistance and roughness formation in ArF photoresist

    Energy Technology Data Exchange (ETDEWEB)

    Jinnai, Butsurin; Uesugi, Takuji; Koyama, Koji; Samukawa, Seiji [Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577 (Japan); Kato, Keisuke; Yasuda, Atsushi; Maeda, Shinichi [Yokohama Research Laboratories, Mitsubishi Rayon Co., Ltd, 10-1 Daikoku-cho, Tsurumi-ku, Yokohama 230-0053 (Japan); Momose, Hikaru, E-mail: samukawa@ifs.tohoku.ac.j [Corporate Research Laboratories, Mitsubishi Rayon Co., Ltd, 2-1 Miyuki-cho, Otake, Hiroshima 739-0693 (Japan)

    2010-10-06

    Low plasma resistance and roughness formation in an ArF photoresist are serious issues in plasma processes. To resolve these issues, we investigated several factors that affect the roughness formation and plasma resistance in an ArF photoresist. We used our neutral beam process to categorize the effects of species from the plasma on the ArF photoresist into physical bombardment, chemical reactions and ultraviolet/vacuum ultraviolet (UV/VUV) radiation. The UV/VUV radiation drastically increased the etching rates of the ArF photoresist films, and, in contrast, chemical reactions increased the formation of surface roughness. FTIR analysis indicated that the UV/VUV radiation preferentially dissociates C-H bonds in the ArF photoresist, rather than C=O bonds, because of the dissociation energies of the bonds. This indicated that the etching rates of the ArF photoresist are determined by the UV/VUV radiation because this radiation can break C-H bonds, which account for the majority of structures in the ArF photoresist. In contrast, FTIR analysis showed that chemical species such as radicals and ions were likely to react with C=O bonds, in particular C=O bonds in the lactone groups of the ArF photoresist, due to the structural and electronic effects of the lactone groups. As a result, the etching rates of the ArF photoresist can vary in different bond structures, leading to increased surface roughness in the ArF photoresist.

  3. 77 FR 42430 - Establishment of Class E Airspace; West Memphis, AR

    Science.gov (United States)

    2012-07-19

    ...-0155; Airspace Docket No. 12-ASW-1] Establishment of Class E Airspace; West Memphis, AR AGENCY: Federal... at West Memphis, AR. Separation of existing Class E airspace surrounding West Memphis Municipal... the West Memphis, AR, area, creating controlled airspace at West Memphis Municipal Airport (77 FR...

  4. 76 FR 53359 - Proposed Establishment of Class E Airspace; Nashville, AR

    Science.gov (United States)

    2011-08-26

    ...-0497; Airspace Docket No. 11-ASW-4] Proposed Establishment of Class E Airspace; Nashville, AR AGENCY... action proposes to establish Class E airspace at Nashville, AR. Controlled airspace is necessary to... approach procedures at Howard County Airport, Nashville, AR. Controlled airspace is needed for the safety...

  5. 75 FR 5904 - Proposed Amendment of Class E Airspace; Magnolia, AR

    Science.gov (United States)

    2010-02-05

    ...-1179; Airspace Docket No. 09-ASW-35] Proposed Amendment of Class E Airspace; Magnolia, AR AGENCY... action proposes to amend Class E airspace at Magnolia, AR. Decommissioning of the Magnolia non-directional beacon (NDB) at Magnolia Municipal Airport, Magnolia, AR, has made this action necessary for the...

  6. Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.

    Science.gov (United States)

    Hsu, Cheng-Lung; Liu, Jai-Shin; Wu, Po-Long; Guan, Hong-Hsiang; Chen, Yuh-Ling; Lin, An-Chi; Ting, Huei-Ju; Pang, See-Tong; Yeh, Shauh-Der; Ma, Wen-Lung; Chen, Chung-Jung; Wu, Wen-Guey; Chang, Chawnshang

    2014-12-01

    Treatment with individual anti-androgens is associated with the development of hot-spot mutations in the androgen receptor (AR). Here, we found that anti-androgens-mt-ARs have similar binary structure to the 5α-dihydrotestosterone-wt-AR. Phage display revealed that these ARs bound to similar peptides, including BUD31, containing an Fxx(F/H/L/W/Y)Y motif cluster with Tyr in the +5 position. Structural analyses of the AR-LBD-BUD31 complex revealed formation of an extra hydrogen bond between the Tyr+5 residue of the peptide and the AR. Functional studies showed that BUD31-related peptides suppressed AR transactivation, interrupted AR N-C interaction, and suppressed AR-mediated cell growth. Combination of peptide screening and X-ray structure analysis may serve as a new strategy for developing anti-ARs that simultaneously suppress both wt and mutated AR function. Copyright © 2014 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

  7. The transcriptional programme of the androgen receptor (AR) in prostate cancer.

    Science.gov (United States)

    Lamb, Alastair D; Massie, Charlie E; Neal, David E

    2014-03-01

    The androgen receptor (AR) is essential for normal prostate and prostate cancer cell growth. AR transcriptional activity is almost always maintained even in hormone relapsed prostate cancer (HRPC) in the absence of normal levels of circulating testosterone. Current molecular techniques, such as chromatin-immunoprecipitation sequencing (ChIP-seq), have permitted identification of direct AR-binding sites in cell lines and human tissue with a distinct coordinate network evident in HRPC. The effectiveness of novel agents, such as abiraterone acetate (suppresses adrenal androgens) or enzalutamide (MDV3100, potent AR antagonist), in treating advanced prostate cancer underlines the on-going critical role of the AR throughout all stages of the disease. Persistent AR activity in advanced disease regulates cell cycle activity, steroid biosynthesis and anabolic metabolism in conjunction with regulatory co-factors, such as the E2F family, c-Myc and signal transducer and activator of transcription (STAT) transcription factors. Further treatment approaches must target these other factors. © 2013 The Authors. BJU International © 2013 BJU International.

  8. AR(p) -based detrended fluctuation analysis

    Science.gov (United States)

    Alvarez-Ramirez, J.; Rodriguez, E.

    2018-07-01

    Autoregressive models are commonly used for modeling time-series from nature, economics and finance. This work explored simple autoregressive AR(p) models to remove long-term trends in detrended fluctuation analysis (DFA). Crude oil prices and bitcoin exchange rate were considered, with the former corresponding to a mature market and the latter to an emergent market. Results showed that AR(p) -based DFA performs similar to traditional DFA. However, the former DFA provides information on stability of long-term trends, which is valuable for understanding and quantifying the dynamics of complex time series from financial systems.

  9. Ideais das crianças mineiras no século XX: mudanças e continuidades

    Directory of Open Access Journals (Sweden)

    Érika Lourenço

    Full Text Available Foi feita, em 1998, a réplica de uma pesquisa realizada entre 1929 e 1944 por Helena Antipoff e em 1993 por Regina Helena de Freitas Campos, com o objetivo de investigar o impacto, nos ideais das crianças de Belo Horizonte, da ênfase que a mídia vem dando ao consumismo na sociedade contemporânea. Um questionário aberto foi aplicado a 307 crianças (151 meninas e 156 meninos da quarta série das escolas públicas e particulares de Belo Horizonte. Os dados referentes aos ideais destas crianças foram submetidos à análise de conteúdo, por gênero, e comparados com os dados das pesquisas anteriores. Foi comprovada a hipótese de que os valores transmitidos pela mídia vêm contribuindo para mudanças nos ideais infantis ao longo do século.

  10. Ideais das crianças mineiras no século XX: mudanças e continuidades

    Directory of Open Access Journals (Sweden)

    Lourenço Érika

    2000-01-01

    Full Text Available Foi feita, em 1998, a réplica de uma pesquisa realizada entre 1929 e 1944 por Helena Antipoff e em 1993 por Regina Helena de Freitas Campos, com o objetivo de investigar o impacto, nos ideais das crianças de Belo Horizonte, da ênfase que a mídia vem dando ao consumismo na sociedade contemporânea. Um questionário aberto foi aplicado a 307 crianças (151 meninas e 156 meninos da quarta série das escolas públicas e particulares de Belo Horizonte. Os dados referentes aos ideais destas crianças foram submetidos à análise de conteúdo, por gênero, e comparados com os dados das pesquisas anteriores. Foi comprovada a hipótese de que os valores transmitidos pela mídia vêm contribuindo para mudanças nos ideais infantis ao longo do século.

  11. Pre-Himalayan tectono-magmatic imprints in the Darjeeling-Sikkim Himalaya (DSH) constrained by 40Ar/39Ar dating of muscovite

    Science.gov (United States)

    Acharyya, Subhrangsu K.; Ghosh, Subhajit; Mandal, Nibir; Bose, Santanu; Pande, Kanchan

    2017-09-01

    The Lower Lesser Himalayan Sequence (L-LHS) in Darjeeling-Sikkim Himalaya (DSH) displays intensely deformed, low-grade meta-sedimentary rocks, frequently intervened by granite intrusives of varied scales. The principal motivation of our present study is to constrain the timing of this granitic event. Using 40Ar/39Ar geochronology, we dated muscovite from pegmatites emplaced along the earliest fabric in the low grade Daling phyllite, and obtained ∼1850 Ma Ar-Ar muscovite cooling age, which is broadly coeval with crystallization ages of Lingtse granite protolith (e.g., 1800-1850 Ma U-Pb zircon ages) reported from the L-LHS. We present here field observations to show the imprints (tectonic fabrics) of multiple ductile deformation episodes in the LHS terrain. The earliest penetrative fabric, axial planar to N-S trending reclined folds, suggest a regional tectonic event in the DSH prior to the active phase of Indo-Asia collision. Based on the age of granitic bodies and their structural correlation with the earliest fabric, we propose that the L-LHS as a distinct convergent tectono-magmatic belt, delineating the northern margin of Indian craton in the framework of the ∼1850 Ma Columbia supercontinent assembly.

  12. A Study on Tracking and Augmentation in Mobile AR for e-Leisure

    Directory of Open Access Journals (Sweden)

    Seong-Wook Jang

    2018-01-01

    Full Text Available Recently, a mobile augmented reality (AR system with AR technology that requires high performance has become popular due to the improved performance of smartphones. In particular, mobile AR that directly interacts with outdoor environments has been in development because of increasing interest in e-leisure due to improvements in living standards. Therefore, this paper aims to study tracking and augmentation in mobile AR for e-leisure. We analyzed the performance of human body tracking application implemented in a mobile system (smartphone using three methods (marker-based, markerless, and sensor-based for the feasibility examination of human body tracking in mobile AR. Furthermore, game information augmentation was examined through the implementation of mobile AR using two methods (marker- and sensor-based.

  13. 75 FR 29656 - Amendment of Class E Airspace; Mountain View, AR

    Science.gov (United States)

    2010-05-27

    ...-1181; Airspace Docket No. 09-ASW-36] Amendment of Class E Airspace; Mountain View, AR AGENCY: Federal... Mountain View, AR. Decommissioning of the Wilcox non-directional beacon (NDB) at Mountain View Wilcox Memorial Field Airport, Mountain View, AR, has made this action necessary to enhance the safety and...

  14. 75 FR 6594 - Proposed Amendment of Class E Airspace; Osceola, AR

    Science.gov (United States)

    2010-02-10

    ...-1183; Airspace Docket No. 09-ASW-38] Proposed Amendment of Class E Airspace; Osceola, AR AGENCY... action proposes to amend Class E airspace at Osceola, AR. Decommissioning of the Osceola non-directional beacon (NDB) at Osceola Municipal Airport, Osceola, AR, has made this action necessary for the safety and...

  15. Alpine orogenic evolution from subduction to collisional thermal overprint: The 40Ar/39Ar age constraints from the Valaisan Ocean, central Alps

    DEFF Research Database (Denmark)

    Wiederkehr, Michael; Sudo, Masafumi; Bousquet, Romain

    2009-01-01

    in general. The timing of high-pressure metamorphism, subsequent retrogression and following Barrow-type overprint was studied by 40Ar/39Ar dating of biotite and several white mica generations that are well characterized in terms of mineral chemistry, texture and associated mineral assemblages. Four distinct...

  16. Ramon Llull's Ars Magna

    DEFF Research Database (Denmark)

    Jensen, Thessa

    2018-01-01

    The Ars Magna of Ramon Llull must be seen as one of the first attempts to formalise language, thought processes, and creating a basis for rational discussions. It consists of so-called principles, concepts, which are defined and combined through the use of four main figures. Llull's contribution...

  17. ARS-Media for Excel

    Science.gov (United States)

    ARS-Media for Excel is an ion solution calculator that uses Microsoft Excel to generate recipes of salts for complex ion mixtures specified by the user. Generating salt combinations (recipes) that result in pre-specified target ion values is a linear programming problem. Thus, the recipes are genera...

  18. Investigation of the energy levels of 38AR

    International Nuclear Information System (INIS)

    Waanders, F.B.

    1975-07-01

    In this project information on the energy levels of 38 Ar was obtained by means of the (p,γ) reaction. The 1,1 MeV Cockroft-Walton accelerator of the Potchefstroom University for CHE was used to produce the proton beam while a 80 cm 3 Ge(Li) detector was used to detect the gamma-rays. Precise gamma-branchings were determined for 50 bound levels, of which four have not previously been determined. These branchings were obtained from the 28 resonances studied in the 37 Cl(p,γ) 38 Ar reaction. The resonance with a proton energy of (592 plus minus 3) keV was not detected previously. The resonance energies, Q-value and energies of the bound levels used in this project were taken from the study done by Alderliesten. The mean lifetimes of a few bound levels of 38 Ar were measured by means of the doppler shift attenuation method. The results concerning the bound states and mean lifetimes are in good agreement with previous experiments. Limitations on the spin and parities of 19 (p,γ) resonances have been set by means of Weisskopf estimates. Only those cases for which the spin could be limited to two values are discussed in the text. A summary of experimental data obtained on 38 Ar is compared with the results from shellmodel calculations done by various workers. A short discussion on the analogue states in 38 Ar is also given [af

  19. Reappraisal of Los Humeros Volcanic Complex by New U/Th Zircon and 40Ar/39Ar Dating: Implications for Greater Geothermal Potential

    Science.gov (United States)

    Carrasco-Núñez, G.; Bernal, J. P.; Dávila, P.; Jicha, B.; Giordano, G.; Hernández, J.

    2018-01-01

    Longevity and size of magmatic systems are fundamental factors for assessing the potential of a geothermal field. At Los Humeros volcanic complex (LHVC), the first caldera-forming event was reported at 460 ± 40 ka. New zircon U/Th and plagioclase 40Ar/39Ar dates of pre-, syn- and postcaldera volcanics allow a reappraisal of the evolution of the geothermally active LHVC. The age of the voluminous Xaltipan ignimbrite (115 km3 dense rock equivalent [DRE]) associated with the formation of the Los Humeros caldera is now constrained by two geochronometers (zircon U/Th and plagioclase 40Ar/39Ar dating) to 164 ± 4.2 ka, which postdates a long episode of precaldera volcanism (rhyolitic domes), the oldest age of which is 693.0 ± 1.9 ka (40Ar/39Ar). The inferred short residence time (around 5 ka) for the paroxysmal Xaltipan ignimbrite is indicative of rapid assembly of a large magma body and rejuvenation of the system due to recurrent recharge magmas, as it has been occurred in some other large magmatic systems. Younger ages than previously believed have been obtained also for the other voluminous explosive phases of the Faby fall tuff at ˜70 ka and the second caldera-forming Zaragoza ignimbrite with 15 km3 DRE, which erupted immediately after. Thus, the time interval that separates the two caldera-forming episodes at Los Humeros is only 94 kyr, which is a much shorter interval than suggested by previous K-Ar dates (410 kyr). This temporal proximity allows us to propose a caldera stage encompassing the Xaltipan and the Zaragoza ignimbrites, followed by emplacement at 44.8 ± 1.7 ka of rhyolitic magmas interpreted to represent a postcaldera, resurgent stage. Rhyolitic eruptions have also occurred during the Holocene (˜1,200 km3) and these new ages indicating much younger caldera-forming volcanism than previously believed are fundamental factors in the application of classical conductive models of heat resource, enhancing the heat production capacity and favor a higher

  20. 41Ar-concentration measurements at the Finnish TRIGA Mark II

    International Nuclear Information System (INIS)

    Tamminen, A.

    1970-01-01

    41 Ar-concentrations in the reactor hall and in the Ar-ventilation duct of FiR-1 (IRIGA Mark II, 250 kW) have been measured during normal operation conditions. Additional measurements have been performed varying Ar-ventilation and hall ventilation flow. A γ- and background compensated thin window proportional detector and a β-Geiger detector for 41 Ar-measurements are described. The hall concentration has also been estimated from background measurements with an unshielded Ge(Li)-detector. The saturation concentration in the reactor hall with and without the hall ventilation is about 1 x 10 -7 μCi/cm 3 and 3 x 10 -7 μCi/cm 3 , respectively. (author)

  1. 40Ar/ 39Ar dating of Late Permian evaporites, southeastern New Mexico, USA

    Science.gov (United States)

    Renne, Paul R.; Sharp, Warren D.; Montañez, Isabel P.; Becker, Tim A.; Zierenberg, Robert A.

    2001-12-01

    40Ar/ 39Ar dating of the potassium-magnesium sulfate mineral langbeinite from Permian evaporites of the Salado formation near Carlsbad, New Mexico, provides quantitative evidence that some salts in these deposits have not recrystallized for 251 Myr since deposition. Survival of Permian salts supports the possibility that Bacillus bacteria recovered from nearby halite was isolated in a closed system and represents a sample of uncontaminated Permian life. Local recrystallization of langbeinite and other nearby minerals is also indicated by the dating, suggesting both the need and the opportunity to document closed system behavior more rigorously. The shoaling and desiccation event recorded by the Salado formation began at least 1 Myr before the Permian-Triassic boundary. Temporal correlation of the Salado with the Zechstein evaporites of north-central Europe supports previously inferred regression models for the origin of these deposits. Significant paleoenvironmental change at the Permian-Triassic boundary thus occurred on a time scale more protracted than that implied by geologically instantaneous events such as bolide impacts.

  2. 75 FR 43884 - Proposed Amendment of Class E Airspace; Searcy, AR

    Science.gov (United States)

    2010-07-27

    ...-1182; Airspace Docket No. 09-ASW-37] Proposed Amendment of Class E Airspace; Searcy, AR AGENCY: Federal... proposes to amend Class E airspace at Searcy, AR. Decommissioning of the Searcy non-directional beacon (NDB) at Searcy Municipal Airport, Searcy, AR, has made this action necessary for the safety and management...

  3. Geochronological 40Ar/39Ar data on the submarine fault-scarps in the Sardinia channel (western mediterranean)

    International Nuclear Information System (INIS)

    Bouillin, J.P.; Tricart, P.; Mascle, G.; Monie, P.; Rolfo, F.; Torelli, L.

    1999-01-01

    Granite and gneiss have been sampled on the submarine fault scarps of the Sardinia Channel and have been dated using the 40 Ar/ 39 Ar method. The majority of rocks partially preserve Hercynian ages. Some of them display Lower Cretaceous ages. In addition, Upper Eocene-Oligocene argon resetting is recorded only in rocks from the southeast sector of the Channel. We thus propose that the basement of the Sardinia Channel occupied a shallow position within the stack of the Alpine tectonic units, behind the more deformed front of the internal zones of the Maghrebide Chain. (authors)

  4. Uso da poeira e do ar como indicadores de contaminação ambiental em áreas circunvizinhas a uma fonte de emissão estacionária de chumbo

    Directory of Open Access Journals (Sweden)

    Quiterio Simone Lorena

    2001-01-01

    Full Text Available Neste trabalho, determinou-se o nível de chumbo (Pb presente no ar em ambientes externos e na poeira doméstica de residências localizadas próximo a uma reformadora de baterias (RB. Uma das principais fontes de exposição ao Pb são empresas do setor de RB, que ainda utilizam processos e tecnologia obsoletos em instalações precárias. Na área externa à RB foram realizadas coletas em seis pontos localizados a aproximadamente 25m e a 500m da RB. Os resultados obtidos mostram que o limite para Pb no ar atmosférico (Pb-Ar de 1,5µg Pb.m-3 foi excedido em 50% das amostras coletadas, variando de 0,03 a 183,3µg Pb.m-3. As coletas nas dependências internas e externas das residências foram realizadas em seis pontos de quatorze residências localizadas a aproximadamente 25m, 50m e a 500m da RB. O limite de Pb na poeira doméstica (Pb-Pd de 1.500µg Pb.m-2 foi excedido em 44% das amostras coletadas, apresentando valores variáveis de 2,2 a 54.338,9µg Pb.m-2.

  5. Uso da poeira e do ar como indicadores de contaminação ambiental em áreas circunvizinhas a uma fonte de emissão estacionária de chumbo

    Directory of Open Access Journals (Sweden)

    Simone Lorena Quiterio

    2001-06-01

    Full Text Available Neste trabalho, determinou-se o nível de chumbo (Pb presente no ar em ambientes externos e na poeira doméstica de residências localizadas próximo a uma reformadora de baterias (RB. Uma das principais fontes de exposição ao Pb são empresas do setor de RB, que ainda utilizam processos e tecnologia obsoletos em instalações precárias. Na área externa à RB foram realizadas coletas em seis pontos localizados a aproximadamente 25m e a 500m da RB. Os resultados obtidos mostram que o limite para Pb no ar atmosférico (Pb-Ar de 1,5µg Pb.m-3 foi excedido em 50% das amostras coletadas, variando de 0,03 a 183,3µg Pb.m-3. As coletas nas dependências internas e externas das residências foram realizadas em seis pontos de quatorze residências localizadas a aproximadamente 25m, 50m e a 500m da RB. O limite de Pb na poeira doméstica (Pb-Pd de 1.500µg Pb.m-2 foi excedido em 44% das amostras coletadas, apresentando valores variáveis de 2,2 a 54.338,9µg Pb.m-2.

  6. Research on AO/FO batch management technology in aircraft production

    Directory of Open Access Journals (Sweden)

    Yin Haijun

    2018-01-01

    Full Text Available Based on the analysis of the characteristics and significance of AO/FO in the process of aircraft production, this paper analyzes the format rules of AO/FO batch management from the perspective of technology realization, and details the AO/FO The change of the query and the change status tracking, introduces the AO/FO single-stand status display in the batch management, increases the structure definition of the attribute table in the batch management, and designs the relevant algorithm to store and calculate the batch information. Finally, based on the above theory support AO/FO batch management system successfully used in the production of a machine.

  7. 40Ar/39Ar dating and zircon chronochemistry for the Izu-Bonin rear arc, IODP site U1437

    Science.gov (United States)

    Schmitt, A. K.; Konrad, K.; Andrews, G. D.; Horie, K.; Brown, S. R.; Koppers, A. A. P.; Busby, C.; Tamura, Y.

    2016-12-01

    The scientific objective of IODP Expedition 350 drilling at Site U1437 (31°47.390'N, 139°01.580'E) was to reveal the "missing half of the subduction factory": the rear arc of a long-lived intraoceanic subduction zone. Site U1437 lies in a 50 km long and 20 km wide volcano-bounded basin, 90 km west of the Izu arc front, and is the only IODP site drilled in the rear arc. The Izu rear arc is dominated by Miocene basaltic to dacitic seamount chains, which strike at a high angle to the arc front. Radiometric dating targeted a single igneous unit (1390 mbsf), and fine to coarse volcaniclastic units for which we present zircon and 40Ar/39Ar (hornblende, plagioclase, and groundmass) age determinations. All zircons analyzed as grain separates were screened for contamination from drill-mud (Andrews et al., 2016) by analyzing trace elements and, where material was available, O and Hf isotope compositions. Igneous Unit 1 is a rhyolite sheet and yielded concordant in-situ and crystal separate U-Pb zircon ages (13.7±0.3 Ma; MSWD = 1.3; n = 40 spots), whereas the 40Ar/39Ar hornblende plateau age (12.9±0.3; MSWD = 1.1; n = 9 steps) is slightly younger, possibly reflecting pre-eruptive zircon crystallization, or alteration of hornblende. U-Pb zircon and 40Ar/39Ar plateau ages from samples above igneous Unit 1 are concordant with biostratigraphic and paleomagnetic ages (available to 1300 mbsf), but plagioclase and groundmass samples below 1300 m become younger with depth, hinting at post-depositional alteration. A single zircon from 1600 mbsf yielded a U-Pb age of 15.4±1.8 Ma; its trace element composition resembles other igneous zircons from U1437, and is tentatively interpreted as a Middle Miocene age for the lowermost lithostratigraphic unit VII. Oxygen and Hf isotopic values of igneous zircon indicate mantle origins, with some influence of assimilation of hydrothermally altered oceanic crust evident in sub-mantle oxygen isotopic compositions. Lessons from site U1437 are

  8. 40Ar/39Ar dating of Quaternary volcanic ashes by multi-collection noble gas mass spectrometry: protocols, precision and intercalibration

    DEFF Research Database (Denmark)

    Storey, Michael; Rivera, Tiffany; Flude, Stephanie

    ) higher mass resolution allows hydrocarbon interferences to be pseudo resolved for the different argon isotopes; and (iv) multi-collection, allowing more data to be gathered in a fixed time in comparison with single-collector peak-switching measurements. We evaluate (i) protocols for detector inter......The recent availability of commercial high-resolution, multi-collector, noble gas mass spectrometers equipped with ion-counting electron multipliers provides new opportunities for improved precision in 40Ar/39Ar dating. This is particularly true for single crystal dating of Quaternary aged samples...... where potassium-bearing phenocrysts may contain relatively small amounts of radiogenic 40Ar. In 2005, the Quaternary Dating Laboratory, Roskilde University, installed a Nu-Instruments multi-collector Noblesse noble gas mass spectrometer, which is configured with a Faraday detector and three ion...

  9. Ars ornata / Kadri Mälk

    Index Scriptorium Estoniae

    Mälk, Kadri, 1958-

    1998-01-01

    V rahvusvaheline ehtekunsti konverents 'Ars ornata Europeana' juuni lõpus Stockholmis. New Yorgis elava kuraatori Charon Kranseni ja prantsuse ehtekunstniku Christophe Burger' juhitud vestlusringidest. 1997. a. Pariisis loodud International Craft Design Association'ist (ICDA).

  10. İMDAT AVŞAR AND HIS STORYTELLING İMDAT AVŞAR VE HİKÂYECİLİĞİ

    Directory of Open Access Journals (Sweden)

    Zehra YAZBAHAR

    2011-01-01

    Full Text Available With his stories in his first book which is Steppe Which Fade To Crocuses he published in 2010, Imdat Avşar reflects our society and our traditional values. In this study which is primarily composed of two major parts, after giving brief information about Imdat Avşar in the first section, the art of storytelling will be part in the second section and the stories in the mentioned book are gotten the grips with narrator, viewpoint, content, characters, language and style. İmdat Avşar, 2010 yılında yayımladığı Çiğdemleri Solan Bozkır isimli ilk hikâye kitabındaki hikâyeleri ile aynasını Türk toplumuna ve onun geleneksel değerlerine tutar. Esas itibariyle iki ana bölümden oluşan bu çalışmada, ilk bölümde İmdat Avşar hakkında kısa bir bilgi verildikten sonra ikinci bölümde hikâyeciliğine geçilecek ve sözü edilen kitabındaki hikâyeleri, anlatıcı ve bakış açısı, içerik ve kişiler kadrosu, dil ve üslûp başlıkları altında ele alınacaktır.

  11. Androgen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells.

    Directory of Open Access Journals (Sweden)

    Congcong Chen

    Full Text Available Androgen receptor (AR signaling is crucial to the development and homeostasis of the prostate gland, and its dysregulation mediates common prostate pathologies. The mechanisms whereby AR regulates growth suppression and differentiation of luminal epithelial cells in the prostate gland and proliferation of malignant versions of these cells have been investigated in human and rodent adult prostate. However, the cellular stress response of human prostate epithelial cells is not well understood, though it is central to prostate health and pathology. Here, we report that androgen sensitizes HPr-1AR and RWPE-AR human prostate epithelial cells to cell stress agents and apoptotic cell death. Although 5α-dihydrotestosterone (DHT treatment alone did not induce cell death, co-treatment of HPr-1AR cells with DHT and an apoptosis inducer, such as staurosporine (STS, TNFt, or hydrogen peroxide, synergistically increased cell death in comparison to treatment with each apoptosis inducer by itself. We found that the synergy between DHT and apoptosis inducer led to activation of the intrinsic/mitochondrial apoptotic pathway, which is supported by robust cleavage activation of caspase-9 and caspase-3. Further, the dramatic depolarization of the mitochondrial membrane potential that we observed upon co-treatment with DHT and STS is consistent with increased mitochondrial outer membrane permeabilization (MOMP in the pro-apoptotic mechanism. Interestingly, the synergy between DHT and apoptosis inducer was abolished by AR antagonists and inhibitors of transcription and protein synthesis, suggesting that AR mediates pro-apoptotic synergy through transcriptional regulation of MOMP genes. Expression analysis revealed that pro-apoptotic genes (BCL2L11/BIM and AIFM2 were DHT-induced, whereas pro-survival genes (BCL2L1/BCL-XL and MCL1 were DHT-repressed. Hence, we propose that the net effect of these AR-mediated expression changes shifts the balance of BCL2-family proteins

  12. O novo sentido do trabalho para o sujeito pós-moderno: uma abordagem crítica

    Directory of Open Access Journals (Sweden)

    Ricardo Henry Dias Rohm

    Full Text Available Análise sobre as maneiras como a sociedade gerencial desenvolve nas mentes uma representação do mundo e da própria pessoa humana, de modo que o único caminho aparente de realização de si consista na lógica da produtividade e em sua relação psíquica e social, tornando a empresa uma referência para a construção do sujeito. Hoje, há necessidade de um eu maleável, sempre aberto a novas experiências; são essas as condições adequadas ao trabalho de curto prazo, a instituições flexíveis e à nova empregabilidade. Esta última constitui um macrodispositivo de controle micropolítico na produção de subjetividades. Richard Sennett afirma que o sentido da vida e da morte não se contabiliza. E é por isso que se deve dar vazão às relações humanas e à satisfação da alma, e não só ao capital, ao capitalismo. Para embasar este artigo, busca-se o caminho de construção da noção de trabalho até alcançar o gerenciamento atual na pós-modernidade. Espera-se, assim, ampliar a compreensão desse fenômeno e viabilizar a produção de métodos mais eficazes e humanizantes da prática de gestão de pessoas nas organizações. Será adotada a pesquisa bibliográfica por meio da revisão de literatura em Ciências Sociais e da Teoria Crítica aplicada à análise da administração na atualidade. A Teoria Crítica busca desenvolver articulações que penetrem a forma e substância, visando questionar a realidade aparente e abarcar a realidade encoberta nas estruturas organizacionais.

  13. Editorial

    Directory of Open Access Journals (Sweden)

    Dilson Ferreira da Cruz

    2008-11-01

    Full Text Available Com este segundo número a Texto Livre procura fazer avançar sua proposta de promover o debate de questões ligadas, de um lado, à tecnologia da informação (TI — com especial atenção ao uso e documentação de softwares livres — e, de outro, às ciências que trabalham com a linguagem e a significação. Como se trata de um campo ainda pouco explorado, pode-se dizer que os autores são uma espécie de desbravadores que abrem trilhas a serem percorridas. Explore-as: O Artigo de Ana Cristina Matte apresenta uma interessante reflexão sobre o que pode haver em comum entre a documentação exigida durante o processo de locação de um imóvel e a documentação que deveria auxiliar o usuário de um software. Daniervelin Pereira analisa alguns softwares educativos procurando assinalar seus aspectos positivos e outros nem tanto, sempre em uma perspectiva que foca questões relacionadas à linguagem. Camila Mantovani aborda as algumas conseqüências decorrentes da multiplicação de medias e o deslocamento do receptor daí decorrente. Será que as múltiplas possibilidades ofertadas pelas novas tecnologias acarretam mudanças nos modelos lingüísticos? O Artigo de Mark Webblink, traduzido por Leonardo Santiago e Alexsandro Meireles, procura elucidar várias questões relacionadas ao uso softwares livre e ao código aberto de programação. Sugere ainda algumas das melhores praticas a serem adotadas por aqueles que desenvolvem ou utilizam softwares livre. Fechando este número, Rainer Krüger discute a importância e os benefícios trazidos pela tradução de software livre, não apenas pelos usuários, mas para os próprios tradutores que, assim, têm a oportunidade de participar do desenvolvimento da ferramenta que utilizam. Boa leitura!

  14. Construtivismo, pluralismo metodológico e formação de professores para o ensino de ciências naturais

    Directory of Open Access Journals (Sweden)

    Marcelo de Carvalho

    2005-12-01

    Full Text Available Com base em renomados autores da área de educação científica, este trabalho procura mostrar que o ideário construtivista não é uma unanimidade no ensino de Ciências Naturais, nos âmbitos epistemológico e ontológico. Assim sendo, definiu-se como problema a ser investigado a seguinte questão: as críticas feitas pelos autores de educação científica aos pressupostos epistemológicos e ontológicos construtivistas, e às suas conseqüências pedagógicas, seria um indicador de que o conhecimento para o ensino de ciências naturais está propenso a ser oriundo não apenas de estratégias centradas no aluno, mas, sim, de um pluralismo metodológico? No sentido de dar uma resposta ao problema, traçaram-se os seguintes objetivos: 1 levantar, analisar e complementar as objeções feitas por vários autores ao construtivismo em educação científica, no campo da epistemologia, ontologia e pedagogia e, 2 de posse dessas críticas, e como conseqüência delas, propor o “pluralismo metodológico” para o ensino das ciências, tomando por base aspectos do “anarquismo epistemológico” de Paul Feyerabend. O procedimento metodológico do trabalho consistiu em: realizar uma busca dos documentos disponíveis na literatura, principalmente livros e artigos científicos e de posse desses materiais, fazer uma reflexão teórica a fim de alcançar os objetivos propostos. Como resultado fica a recomendação de uma educação científica e, principalmente, dos métodos de ensino a ela associados, não-fixos a sistemas rígidos e limitados, mas que estejam abertos à crítica e a todas as novas descobertas e experiências inovadoras da área.

  15. $\\beta$ decay of $^{47}$Ar

    CERN Document Server

    Weissman, L; Bergmann, U C; Brown, B A; Catherall, R; Cederkäll, J; Dillmann, I; Hallmann, O; Fraile-Prieto, L M; Franchoo, S; Gaudefroy, L; Köster, U; Kratz, K L; Pfeiffer, B; Sorlin, O; 10.1103/PhysRevC.70.024304

    2004-01-01

    Information on beta -decay properties of neutron-rich /sup 47/Ar was obtained at the ISOLDE facility at CERN using isobaric selectivity. This was achieved by a combination of a plasma-ion source with a cooled transfer line and subsequent mass separation. A doubly charged beam was used in order to improve the signal-to-background ratio associated with multi-charged noble gas fission products. The identification of the /sup 47/Ar gamma -ray transitions was performed by comparing the spectra obtained from direct proton bombardment of the target and of the neutron converter. New excited levels in the daughter /sup 47/K nucleus corresponding to the negative-parity states were observed. The obtained data are compared to the result of large-scale shell model calculations and quasiparticle random-phase approximation predictions. (29 refs).

  16. Acoustic Resonance Spectroscopy (ARS) Munition Classification System enhancements. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Vela, O.A.; Huggard, J.C.

    1997-09-18

    Acoustic Resonance Spectroscopy (ARS) is a non-destructive evaluation technology developed at the Los Alamos National Laboratory (LANL). This technology has resulted in three generations of instrumentation, funded by the Defense Special Weapons Agency (DSWA), specifically designed for field identification of chemical weapon (CW) munitions. Each generation of ARS instrumentation was developed with a specific user in mind. The ARS1OO was built for use by the U.N. Inspection Teams going into Iraq immediately after the Persian Gulf War. The ARS200 was built for use in the US-Russia Bilateral Chemical Weapons Treaty (the primary users for this system are the US Onsite Inspection Agency (OSIA) and their Russian counterparts). The ARS300 was built with the requirements of the Organization for the Prohibition of Chemical Weapons (OPCW) in mind. Each successive system is an improved version of the previous system based on learning the weaknesses of each and, coincidentally, on the fact that more time was available to do a requirements analysis and the necessary engineering development. The ARS300 is at a level of development that warrants transferring the technology to a commercial vendor. Since LANL will supply the computer software to the selected vendor, it is possible for LANL to continue to improve the decision algorithms, add features where necessary, and adjust the user interface before the final transfer occurs. This paper describes the current system, ARS system enhancements, and software enhancements. Appendices contain the Operations Manual (software Version 3.01), and two earlier reports on enhancements.

  17. C5a and C5aR are elevated in joints of rheumatoid and psoriatic arthritis patients, and C5aR blockade attenuates leukocyte migration to synovial fluid

    DEFF Research Database (Denmark)

    Hornum, Lars; Hansen, Anker Jon; Tornehave, Ditte

    2017-01-01

    synovial fluid was significantly inhibited by anti-C5aR. The data support that the C5a-C5aR axis may be driving the infiltration of inflammatory cells into the synovial fluid and synovium in both rheumatoid and psoriatic arthritis, and suggest that C5a or C5aR may be a promising treatment target in both...... a Boyden chamber. Appropriate statistical tests were applied for comparisons. C5aR+ cells were detected in most rheumatoid arthritis, in all psoriatic arthritis, but not in non-inflammatory control synovia. C5aR+ cells were primarily neutrophils and macrophages. C5aR+ macrophages were mainly found...

  18. K/Ar dating of diagenetic illites

    International Nuclear Information System (INIS)

    Mizusaki, A.M.P.; Anjos, S.M.C. dos; Costa, M.G.F. da; Silva, O.B. da; Kawashita, K.

    1990-01-01

    Ascertaining the potassium/argon (K/Ar) age of diagenetic illites yields important information for hydrocarbon exploration since the growth of this mineral in the pores of sandstone reservoir and oil migration are interlinked events in the diagenetic evolution of rocks. Illite growth ceases as soon as hydrocarbons completely fill in rock pores, displacing interstitial water. By providing an estimate of the period when the illite formed, K/Ar dating can indirectly tells us when hydrocarbons entered the reservoir. Samples of oil-saturated sandstones collected from Carboniferous reservoirs of the Solimoes Basin reveal a diagenetic evolution consisting predominantly of quartz, calcite, and illite overgrowths. In the present study, illite was mechanically separated by repeating a series of ultrasonic baths and ultrasonic probes followed by high-speed centrifuging. Resultant fractions were analyzed by X-ray diffractometry to measure the illite content of each sample. The separated illite material was found to be composed of illite and ordered mixed layer illite-smectite with 80% illite layers. Separated fractions were dated radiometrically by the K/Ar method. Preliminary results indicate an average age of some 200 m.y., which marks the end of the diagenetic development of the illites of this area. (author)

  19. 40Ar/39Ar dating and paleo-magnetism of traps from Ethiopia, Deccan and Siberia

    International Nuclear Information System (INIS)

    Hofmann, C.

    1997-01-01

    Recent studies have shown that major flood basalt provinces have been emplaced as short events (∼ 1 Myr), more or less synchronous with climatic crises and mass extinctions. We present new geochronologic ( 40 Ar/ 39 Ar) and magneto-stratigraphic results for the Ethiopian traps, one of the last remaining flood basalts for which little of such data were available. The ages obtained in a 2000 m thick section are indistinguishable. Moreover, magneto-stratigraphy reveals a simple 3-chron reverse-normal-reverse sequence. Although magnetic chrons cannot be yet unambiguously identified, there is more likelihood for the normal sub-chron in the main basaltic pile to correspond to 11N, supporting a brief duration (less than 1.5 Ma). The Ethiopian traps erupted near 30 Ma at or near the time of the cold and dry climate, major Antarctic ice sheet advance, and the largest sea-level drop in the Tertiary. Bhandari et al. (GRL, 1995) have discovered inter-traps sediments with a triple iridium anomaly in a series of seven basaltic lava flows in the Kutch area of the North Western Deccan traps of India. Plagioclases from three flows above the iridium bearing sediments yield 39 Ar/ 40 Ar plateau ages near 65.0 Ma: these flows have unambiguously reversed magnetic polarity interpreted as chron 29R. As a preliminary summary, evidence of the KTB asteroid impact is confirmed in the Deccan traps, showing that they are coeval events in a general sense (in a Ma long window) though clearly with vastly different time constants. This is compatible with paleontologic evidence of two scales of extinctions, one quasi-instantaneous and the other on the order of 10 5 to 10 6 yrs. Clearly, the impact cannot have caused trap eruptions. On the other hand, the exact age and significance of the lower flows more altered remains to be analyzed further as they pertained to the much debated question of duration of Deccan trap volcanism. (author)

  20. Programa computacional para a estimativa da temperatura do ar para a região Nordeste do Brasil A computer program to estimate air temperature for Northeast region of Brazil

    Directory of Open Access Journals (Sweden)

    Enilson P. Cavalcanti

    2006-03-01

    Full Text Available A meta principal através desta pesquisa foi estabelecer modelo de estimativa de temperatura do ar (Estima_T em função das coordenadas geográficas e das Anomalias de Temperaturas da Superfície do Mar (ATSM. Neste estudo foram utilizadas as séries temporais das médias mensais de temperatura do ar (média diária, mínima e máxima de 69 estações meteorológicas do Nordeste do Brasil (NEB e ATSM do oceano Atlântico Tropical. O modelo Estima_T mostrou-se capaz de reconstruir séries temporais de temperatura do ar com razoável precisão para todo o NEB. Os resultados mostraram correlações estatisticamente significantes ao nível de 1% de probabilidade entre as temperaturas do ar observada e estimada pelo modelo, em toda a região de estudo.The objective of this research was to establish a model to estimate air temperature (Estima_T as a function of geographical coordinates and Sea Surface Temperature Anomalies (SSTA. The mean monthly time series of air temperatures (daily mean, minimum and maximum of 69 weather stations and SSTA of the Tropical Atlantic were analyzed. The model Estima_T showed good agreement between real and estimated air temperature data of Northeast Brazil. The results showed statistically significant correlation at 1% level between observed air temperatures and those estimated by model in the whole area of study.

  1. Ar-41 measurements and nuclear emergency preparedness

    International Nuclear Information System (INIS)

    Kunst, J.J.; Rodriguez, M.; Ugarte, R.; Vigile, R.S.; Boutet, L.I.; Jordan, O.D.; Hernandez, D.G.

    2010-01-01

    During the early phase of an emergency is necessary to confirm the release of radioactivity predictions made by the operator of the nuclear plant. In this context, it has begun measuring Ar-41 in the vicinity of a research reactor. Since the Ar-41 is produced in the reactor, it has been studied as a good way to validate the air dispersion model used in nuclear emergencies and to develop a method to improve the characterization of the release. For this latter purpose a pilot experiment was conducted to determine computational and experimental methods, the flux of 1.29 MeV of Ar-41 and compared to evaluate the accuracy of the assessments made. This paper describes meteorological forecasting systems used in the experiment, the estimate of the stability class and the concentration of nuclides using a calculation code developed by the ARN, as well as the methodology and equipment used for measurement in the field. (authors) [es

  2. Collisional excitation of ArH+ by hydrogen atoms

    Science.gov (United States)

    Dagdigian, Paul J.

    2018-06-01

    The rotational excitation of the 36ArH+ ion in collisions with hydrogen atoms is investigated in this work. The potential energy surface (PES) describing the 36ArH+-H interaction, with the ion bond length r fixed at the average of r over the radial v = 0 vibrational state distribution, was obtained with a coupled cluster method that included single, double, and (perturbatively) triple excitations [RCCSD(T)]. A deep minimum (De = 3135 cm-1) in the PES was found in linear H-ArH+ geometry at an ion-atom separation Re = 4.80a0. Energy-dependent cross-sections and rate coefficients as a function of temperature for this collision pair were computed in close-coupling (CC) calculations. Since the PES possesses a deep well, this is a good system to test the performance of the quantum statistical (QS) method developed by Manolopoulos and co-workers as a more efficient method to compute the cross-sections. Good agreement was found between rate coefficients obtained by the CC and QS methods at several temperatures. In a simple application, the excitation of ArH+ is simulated for conditions under which this ion is observed in absorption.

  3. The Educational Values of Athiyyah ar-Rahman Book

    Directory of Open Access Journals (Sweden)

    Maya Yunita

    2018-04-01

    Full Text Available Athiyyah ar-Rahman is an influential book which written by Muhammad Azhari al-Palembani ibn Abdullah ibn Ahmad or also known as Kemas Azhari (1811-1874. The book was written in 1842 and until today is learned by Islamic community in Palembang. This article tries to elucidate the values of Athiyyah ar-Rahman book from education perspectives. The discourse-historical approach of Reisigl and Wodak (2008 is used to analyze the book. The findings show that Athiyyah ar-Rahman describes six pillars of Islam. The six pillars of Islam are framing three dimensions, including personal dimension, social dimension, and transformative dimension. The personal dimension relates to the core of the education to construct the self of student. The social dimension relates to the visions for harmonizing among humans and between humans and nature. Meanwhile, the transformational dimension relates to the effect of education to solve the problems in human life as well as transform the society. Based on the analysis, the educational values of Athiyyah ar-Rahman could be summarized as follows: religiosity, spirituality, morality, solidarity, tolerance, environmentalism, pragmatism and transformational.

  4. Audit, Control and Monitoring Design Patterns (ACMDP for Autonomous Robust Systems (ARS

    Directory of Open Access Journals (Sweden)

    C. Trad

    2008-11-01

    Full Text Available This paper proposes the Audit, Control and Monitoring Design Patterns (ACMDP for building Autonomous and Robust Systems (ARS such as Mobile Robot Systems (MRS. These patterns are also applicable to other Mission Critical and Complex Systems (MCCS. This paper presents a proposal which will help ARS project managers and engineers design, build and estimate the probability that an ARS will succeed or fail. Furthermore, this proposal offers the possibility to ARS problems with the help of audit, monitoring and controlling components, adjust the project management pathways, and define the problem sources as well as their possible solutions, in order to deliver an ARS or an MRS.

  5. Variação anual na abertura do dossel, temperatura e umidade do ar no sub-bosque de três ambientes florestais no sul da Bahia, Brasil

    Directory of Open Access Journals (Sweden)

    Marayana Prado Pinheiro

    2013-03-01

    Full Text Available http://dx.doi.org/10.5902/198050988445Visando contribuir para o conhecimento dos fatores físicos que afetam a estrutura da comunidade vegetal em remanescentes de mata atlântica do sul da Bahia foi analisada a variação anual do microclima do sub-bosque num fragmento de floresta de encosta na Reserva Particular do Patrimônio Natural Serra do Teimoso (RST e num sistema agroflorestal rústico utilizado para o cultivo do cacau (Cabruca, localizado nas proximidades da RST. Dados da abertura do dossel (CO, da temperatura do ar (Ta, da umidade relativa do ar (RH e do déficit de pressão de vapor (VPD foram coletados entre abril de 2005 e abril de 2006 na base (RSTB, 340 m e no topo (RSTT, 640 m da RST e na Cabruca (CB, 250 m. Dados de precipitação pluvial, Ta, RH e VPD foram também coletados numa área aberta (OA, 270 m. As maiores precipitações (> 100 mm ocorreram em Novembro de 2005 e Abril de 2006, enquanto outubro de 2005 foi o mês mais seco (< 20 mm. CO variou entre 2,5% na CB (Abril, 2006 e 7,7% na RST (Outubro, 2005. Os baixos valores de pluviosidade registrados em Outubro de 2005 afetaram VPDmax em todos os ambientes. Estes efeitos foram mais pronunciados em OA, seguido de CB, RSTB e RSTT. Os valores de Ta, RH e VPD em CB foram mais próximos aos valores observados em OA do que aos valores observados no interior da floresta.

  6. Episodic Holocene eruption of the Salton Buttes rhyolites, California, from paleomagnetic, U-Th, and Ar/Ar dating

    Science.gov (United States)

    Wright, Heather M.; Vazquez, Jorge A.; Champion, Duane E.; Calvert, Andrew T.; Mangan, Margaret T.; Stelten, Mark E.; Cooper, Kari M.; Herzig, Charles; Schriener Jr., Alexander

    2015-01-01

    In the Salton Trough, CA, five rhyolite domes form the Salton Buttes: Mullet Island, Obsidian Butte, Rock Hill, North and South Red Hill, from oldest to youngest. Results presented here include 40Ar/39Ar anorthoclase ages, 238U-230Th zircon crystallization ages, and comparison of remanent paleomagnetic directions with the secular variation curve, which indicate that all domes are Holocene. 238U-230Th zircon crystallization ages are more precise than but within uncertainty of 40Ar/39Ar anorthoclase ages, suggesting that zircon crystallization proceeded until shortly before eruption in all cases except one. Remanent paleomagnetic directions require three eruption periods: (1) Mullet Island, (2) Obsidian Butte, and (3) Rock Hill, North Red Hill, and South Red Hill. Borehole cuttings logs document up to two shallow tephra layers. North and South Red Hills likely erupted within 100 years of each other, with a combined 238U-230Th zircon isochron age of: 2.83 ± 0.60 ka (2 sigma); paleomagnetic evidence suggests this age predates eruption by hundreds of years (1800 cal BP). Rock Hill erupted closely in time to these eruptions. The Obsidian Butte 238U-230Th isochron age (2.86 ± 0.96 ka) is nearly identical to the combined Red Hill age, but its Virtual Geomagnetic Pole position suggests a slightly older age. The age of aphyric Mullet Island dome is the least well constrained: zircon crystals are resorbed and the paleomagnetic direction is most distinct; possible Mullet Island ages include ca. 2300, 5900, 6900, and 7700 cal BP. Our results constrain the duration of Salton Buttes volcanism to between ca. 5900 and 500 years.

  7. Substituent effect in spin-crossover behavior of iron(II)-Ar-pybox complexes (Ar-pybox = 4-aryl-2,6-bis(oxazolin-2-yl)pyridine)

    Science.gov (United States)

    Kimura, Akifumi; Ishida, Takayuki

    2018-01-01

    Spin-crossover (SCO) is a reversible transition between low-spin (LS) and high-spin (HS) states by external stimuli like heat. The SCO behavior of [Fe(Ar-pybox)2](ClO4)2 was investigated, where Ar-pybox stands for 4-aryl-2,6-bis(oxazolin-2-yl)pyridine with Ar = 4-pyridyl (4Py), 3-thienyl (3Th), and phenyl (Ph). They were characterized by means of single-crystal X-ray diffraction study, being consistent with the results of the magnetic measurements. The SCO temperatures (T1/2) in the polycrystalline state were determined to be 360 and 230 K for Ar = 4Py and Ph, respectively. The 3Th derivative possessed a HS state in all the temperature range. The solution susceptometry was also performed to purge intermolecular interaction and rigid crystal lattice effects, affording T1/2 = 310, 240, and 240 K for Ar = 4Py, 3Th, and Ph, respectively, in acetone. The substituent effect analysis using the Hammett substituent constant (σp) clarified that electron-withdrawing groups raise T1/2. A plausible model describing the substituent effect on T1/2 is proposed based on d-π interaction. The present result is regarded as a successful example of crystal field engineering.

  8. The AR Sandbox: Augmented Reality in Geoscience Education

    Science.gov (United States)

    Kreylos, O.; Kellogg, L. H.; Reed, S.; Hsi, S.; Yikilmaz, M. B.; Schladow, G.; Segale, H.; Chan, L.

    2016-12-01

    The AR Sandbox is a combination of a physical box full of sand, a 3D (depth) camera such as a Microsoft Kinect, a data projector, and a computer running open-source software, creating a responsive and interactive system to teach geoscience concepts in formal or informal contexts. As one or more users shape the sand surface to create planes, hills, or valleys, the 3D camera scans the surface in real-time, the software creates a dynamic topographic map including elevation color maps and contour lines, and the projector projects that map back onto the sand surface such that real and projected features match exactly. In addition, users can add virtual water to the sandbox, which realistically flows over the real surface driven by a real-time fluid flow simulation. The AR Sandbox can teach basic geographic and hydrologic skills and concepts such as reading topographic maps, interpreting contour lines, formation of watersheds, flooding, or surface wave propagation in a hands-on and explorative manner. AR Sandbox installations in more than 150 institutions have shown high audience engagement and long dwell times of often 20 minutes and more. In a more formal context, the AR Sandbox can be used in field trip preparation, and can teach advanced geoscience skills such as extrapolating 3D sub-surface shapes from surface expression, via advanced software features such as the ability to load digital models of real landscapes and guiding users towards recreating them in the sandbox. Blueprints, installation instructions, and the open-source AR Sandbox software package are available at http://arsandbox.org .

  9. Arsenic phytoextraction and hyperaccumulation by fern species Fitoextração e hiperacumulação de arsênio por espécies de samambaias

    Directory of Open Access Journals (Sweden)

    Maria Isidoria Silva Gonzaga

    2006-02-01

    Full Text Available Arsenic (As is an ubiquitous trace metalloid found in all environmental media. Its presence at elevated concentrations in soils derives from both anthropogenic and natural inputs. Arsenic is a toxic and carcinogenic element, which has caused severe environmental and health problem worldwide. Technologies currently available for the remediation of arsenic-contaminated sites are expensive, environmentally disruptive, and potentially hazardous to workers. Phytoextraction, a strategy of phytoremediation, uses plants to clean up contaminated soils and has been successfully applied to arsenic contaminated soils. It has the advantage of being cost-effective and environmentally friendly. A major step towards the development of phytoextraction of arsenic-impacted soils is the discovery of the arsenic hyper accumulation in ferns, first in Pteris vittata, which presented an extraordinary capacity to accumulate 2.3% arsenic in its biomass. Another fern, Pityrogramma calomelanos was found to exhibit the same hyperaccumulating characteristics. After that, screening experiments have revealed that the Pteris genus is really unique in that many species have the potential to be used in phytoextraction of arsenic. In general, these plants seem to have both constitutive and adaptive mechanisms for accumulating or tolerating high arsenic concentration. In the past few years, much work has been done to understand and improve the hyperaccumulating capability of these amazing plants. In particular, the field of molecular biology seems to hold the key for the future of the phytoremediation.O arsênio e um metalóide traço encontrado basicamente em todos os ambientes. Elevadas concentrações de arsênio no solo podem acontecer naturalmente devido ao intemperismo de rochas ricas em arsênio, como também de atividades antropogênicas. O arsênio é um elemento tóxico e cancerígeno. Em muitas partes do mundo, a contaminação pelo arsênio tem causado problemas

  10. Novel galeterone analogs act independently of AR and AR-V7 for the activation of the unfolded protein response and induction of apoptosis in the CWR22Rv1 prostate cancer cell model.

    Science.gov (United States)

    McCarty, David J; Huang, Weiliang; Kane, Maureen A; Purushottamachar, Puranik; Gediya, Lalji K; Njar, Vincent C O

    2017-10-24

    The androgen receptor (AR) has long been the primary target for the treatment of prostate cancer (PC). Despite continuous efforts to block AR activity through ligand depletion, AR antagonism, AR depletion and combinations thereof, advanced PC tumors remain resilient. Herein, we evaluate two galeterone analogs, VNPT-178 and VNLG-74A, in PC cell models of diverse androgen and AR dependence attempting to delineate their mechanisms of action and potential clinical utility. Employing basic biochemical techniques, we determined that both analogs have improved antiproliferative and anti-AR activities compared to FDA-approved abiraterone and enzalutamide. However, induction of apoptosis in these models is independent of the AR and its truncated variant, AR-V7, and instead likely results from sustained endoplasmic reticulum stress and deregulated calcium homeostasis. Using in silico molecular docking, we predict VNPT-178 and VNLG-74A bind the ATPase domain of BiP/Grp78 and Hsp70-1A with greater affinity than the AR. Disruption of 70 kDa heat shock protein function may be the underlying mechanism of action for these galeterone analogs. Therefore, despite simultaneously antagonizing AR activity, AR and/or AR-V7 expression alone may inadequately predict a patient's response to treatment with VNPT-178 or VNLG-74A. Future studies evaluating the context-specific limitations of these compounds may provide clarity for their clinical application.

  11. On the relationship between atmospheric rivers (ARs) and heavy precipitation over Japan

    Science.gov (United States)

    Yatagai, A. I.; Takayabu, Y. N.

    2016-12-01

    Atmospheric Rivers (ARs) are known as the water-vapor rich part of the broader warm conveyor belt. Recently, several AR detection algorithms are proposed, and structures and that of statistical features are studied globally. Since Japan is a humid country located in the north of the warm pool, ARs, middle tropospheric fast moisture transport, might be an important moisture source for heavy precipitation events in Japan. The purpose of this study is to develop an algorithm of detection of ARs over Japan, and to investigate the possible relationship between them and Japanese heavy precipitation events. Since high spatial correlations were obtained between ERA-Interim reanalysis PW and that of SSM/I (microwave images), we used daily PW (0.75 degree grid) for detection of the ARs. Using 36 years (1979-2014) ERA-Interim, we defined daily smoothed PW climatology. Then, we detected AR area with daily anomaly of PW exceeding 10 mm. However, we exclude round-shaped (caused by Typhoon etc) area and the case of moisture transport not exceeding 30N/30S. The daily AR events over Japan (123-146E, 24-46N) are; 1013 cases for winter (DJF), 1722 for spring (MAM), 2229 for summer (JJA) and 1870 for autumn (SON) during the 36 years. They successfully include Hiroshima disaster event (19 August 2014, Hirota et al., 2015) and Amami heavy precipitation event (20 October 2010). The summer with large AR appearance (1998 and 2010) had negative SOI (La Nina), and lowest appearance year (1992) was the year of El Nino (positively significant SOI). Totally, more ARs come over Japan area in La Nina years, however, the seasonal statistics between SOI and the number of AR is not straightforward, indicating that it is difficult to explain ARs over Japan with only tropical inter-annual variability. We use APHRO-JP (Kamiguchi et al., 2010) daily gridded (0.05 degree) precipitation (1979-2011) over Japanese land areas for comparison. Among the 32 years (1979-2011), we had 82 cases of heavy

  12. Microbiological air quality of processing areas in a dairy plant as evaluated by the sedimentation technique and a one-stage air sampler Qualidade microbiológica do ar de ambientes de processamento em indústria de laticínios avaliada por amostrador de ar de um estágio e pela técnica da sedimentação

    Directory of Open Access Journals (Sweden)

    Valéria Costa Salustiano

    2003-07-01

    ância de fungos filamentosos e leveduras pela técnica de sedimentação em ágar e de mesófilos aeróbios pela de impressão em ágar. O aumento da temperatura ambiente, ao contrário do aumento da umidade relativa do ar, não contribuiu para maiores contagens microbianas no ar.

  13. SCExAO: First Results and On-Sky Performance

    Science.gov (United States)

    Currie, Thayne; Guyon, Olivier; Martinache, Frantz; Clergeon, Christophe; McElwain, Michael; Thalmann, Christian; Jovanovic, Nemanja; Singh, Garima; Kudo, Tomoyuki

    2013-01-01

    We present new on-sky results for the Subaru Coronagraphic Extreme Adaptive Optics imager (SCExAO) verifying and quantifying the contrast gain enabled by key components: the closed-loop coronagraphic low-order wavefront sensor (CLOWFS) and focal plane wavefront control ("speckle nulling"). SCExAO will soon be coupled with a high-order, Pyramid wavefront sensor which will yield greater than 90% Strehl ratio and enable 10(exp 6) -10(exp 7) contrast at small angular separations allowing us to image gas giant planets at solar system scales. Upcoming instruments like VAMPIRES, FIRST, and CHARIS will expand SCExAO's science capabilities.

  14. A Knock-in Reporter for a Novel AR-Targeted Therapy

    Science.gov (United States)

    2016-05-01

    AWARD NUMBER: W81XWH-15-1-0049 TITLE: A Knock -in Reporter for a Novel AR-Targeted Therapy PRINCIPAL INVESTIGATOR: Chunhong Yan, Ph.D...5a. CONTRACT NUMBER A Knock -in Reporter for a Novel AR-Targeted Therapy 5b. GRANT NUMBER W81XWH-15-1-0049 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...enhancer. While the knock -in reporter is expected to faithfully reproduce chemical responses of the endogenous AR gene, we carried out a pilot screen

  15. Educação, Cidadania e Trabalho: o Novo Plano Nacional de Educação e os desafios educacionais com vistas ao Desenvolvimento Humano.

    Directory of Open Access Journals (Sweden)

    Afonso Soares Oliveira Sobrinho

    2015-12-01

    Full Text Available Geração após geração, ouvimos um discurso de educação de qualidade conforme previsão legal. No entanto, há impasses do processo ensino-aprendizagem, a começar pelo distanciamento do discurso à realidade escolar onde temos o professor e o gestor que, em regra, vivenciam práticas culturais escolares baseadas na perspectiva analógica do século XX. Por sua vez, a estrutura escolar advém de uma lógica de vigilância e disciplina do século XIX. Pari passo as dimensões culturais intergeracionais e seus conflitos identifica-se um aluno da era digital focado na ética e estética do consumo. Assim, advém a necessidade de rupturas quanto ao olhar etnocêntrico dos diversos sujeitos sociais pelo aprendizado compartilhado (professores, alunos, gestores, comunidade. Há, portanto, a necessidade da escola se abrir ao diálogo respeitoso e sem preconceitos, com vistas ao desenvolvimento humano. A educação no século XXI orienta-se na concepção inclusiva, da diversidade e pluralismo cultural. A escola democrática se faz pela práxis que vislumbre uma aprendizagem significativa e permita o desenvolvimento humano. Nesse diapasão, encontramos inserido o Novo Plano Nacional de Educação como instrumento discursivo que vislumbra uma educação de qualidade.

  16. Irradiation effects of Ar cluster ion beams on Si substrates

    International Nuclear Information System (INIS)

    Ishii, Masahiro; Sugahara, Gaku; Takaoka, G.H.; Yamada, Isao

    1993-01-01

    Gas-cluster ion beams can be applied to new surface modification techniques such as surface cleaning, low damage sputtering and shallow junction formation. The effects of energetic Ar cluster impacts on solid surface were studied for cluster energies of 10-30keV. Irradiation effects were studied by RBS. For Si(111) substrates, irradiated with Ar ≥500 clusters to a dose of 1x10 15 ion/cm 2 at acceleration voltage 15kV, 2x10 14 atoms/cm 2 implanted Ar atoms were detected. In this case, the energy per cluster atom was smaller than 30eV; at this energy, no significant implantation occurs in the case of monomer ions. Ar cluster implantation into Si substrates occurred due to the high energy density irradiation. (author)

  17. K/Ar and 40Ar/39Ar dating of emerald mineralizations from Brazil. Evidence of Transamazonian (2 Ga) and Brazilian (650 - 500 Ma) ages. Influence of phlogopite crystallo-chemistry on argon retention

    International Nuclear Information System (INIS)

    Ribeiro-Althoff, A.M.

    1997-01-01

    The emerald deposits of Brazil are always found within basic and ultra-basic formations which have been metasomatized by hydrothermal fluids, and transformed into phlogopitites. Two types of deposits may be distinguished: one associated with pegmatites, the other with shear zones. In both cases the precipitation of emerald is contemporaneous with that of phlogopite. The age of these has been determined by dating of the latter, using K-Ar and 40 Ar/ 39 Ar methods. Deposits associated with pegmatite have ages between 2.0 et 1.9 Ga (Carnaiba, Socoto), and between 650 et 500 Ma (Pombos, Juca, Pirenoplis, Capoeirana, Coqui). The Santa Terezinha deposit, associated with a shear zone where pegmatites are absent, gives an age of formation of 520 Ma. These results show that brazilian emeralds were formed during two distinct orogenic periods: the Transamazonian (2.0 Ga), in the Sao Francisco craton, and the Brasilian (650 - 500 Ma)

  18. Ar Rahman-Based Dysmenorrhea Gymnastic to Reduce Pain

    OpenAIRE

    Sumaryani, Sri; Puspita Sari, Praditiana Indah

    2015-01-01

    Introduction: More than 50% dysmenorrhea are caused by excessive amounts of prostaglandin hormone during menstruation.  The combination of dysmenorrhea gymnastics and Qur'an Surah Ar-Rahman relaxation techniques is a new innovation in non-pharmacological therapy to overcome dysmenorrhoea. The purpose of this study was to determine the level of pain differences on respondents who were given dysmenorrhea gymnastics treatment, Al Quran Surah Ar-Rahman recitation, and dysmenorrhea gymnastics comb...

  19. Low energy total cross section of 36Ar

    International Nuclear Information System (INIS)

    Mughabghab, S.F.; Magurno, B.A.

    1975-01-01

    To compare the predictions of the valence model with measured partial radiative widths of 36 Ar an accurate knowledge of the bound-level parameters is required. This is achieved by carrying out a Breit-Wigner parameter fit to the total cross section of 36 Ar measured by Chrien et al and renormalized to the recommended values of the thermal capture and scattering cross sections. (1 figure, 1 table) (U.S.)

  20. Aurora Kinase A Promotes AR Degradation via the E3 Ligase CHIP.

    Science.gov (United States)

    Sarkar, Sukumar; Brautigan, David L; Larner, James M

    2017-08-01

    Reducing the levels of the androgen receptor (AR) is one of the most viable approaches to combat castration-resistant prostate cancer. Previously, we observed that proteasomal-dependent degradation of AR in response to 2-methoxyestradiol (2-ME) depends primarily on the E3 ligase C-terminus of HSP70-interacting protein (STUB1/CHIP). Here, 2-ME stimulation activates CHIP by phosphorylation via Aurora kinase A (AURKA). Aurora A kinase inhibitors and RNAi knockdown of Aurora A transcript selectively blocked CHIP phosphorylation and AR degradation. Aurora A kinase is activated by 2-ME in the S-phase as well as during mitosis, and phosphorylates CHIP at S273. Prostate cancer cells expressing an S273A mutant of CHIP have attenuated AR degradation upon 2-ME treatment compared with cells expressing wild-type CHIP, supporting the idea that CHIP phosphorylation by Aurora A activates its E3 ligase activity for the AR. These results reveal a novel 2-ME→Aurora A→CHIP→AR pathway that promotes AR degradation via the proteasome that may offer novel therapeutic opportunities for prostate cancer. Mol Cancer Res; 15(8); 1063-72. ©2017 AACR . ©2017 American Association for Cancer Research.

  1. {sup 40}Ar/{sup 39}Ar dating and paleo-magnetism of traps from Ethiopia, Deccan and Siberia; Datation {sup 40}Ar/{sup 39}Ar et paleomagnetisme des traps d'Ethiopie, du Deccan et de Siberie

    Energy Technology Data Exchange (ETDEWEB)

    Hofmann, C

    1997-01-01

    Recent studies have shown that major flood basalt provinces have been emplaced as short events ({approx} 1 Myr), more or less synchronous with climatic crises and mass extinctions. We present new geochronologic ({sup 40}Ar/{sup 39}Ar) and magneto-stratigraphic results for the Ethiopian traps, one of the last remaining flood basalts for which little of such data were available. The ages obtained in a 2000 m thick section are indistinguishable. Moreover, magneto-stratigraphy reveals a simple 3-chron reverse-normal-reverse sequence. Although magnetic chrons cannot be yet unambiguously identified, there is more likelihood for the normal sub-chron in the main basaltic pile to correspond to 11N, supporting a brief duration (less than 1.5 Ma). The Ethiopian traps erupted near 30 Ma at or near the time of the cold and dry climate, major Antarctic ice sheet advance, and the largest sea-level drop in the Tertiary. Bhandari et al. (GRL, 1995) have discovered inter-traps sediments with a triple iridium anomaly in a series of seven basaltic lava flows in the Kutch area of the North Western Deccan traps of India. Plagioclases from three flows above the iridium bearing sediments yield {sup 39}Ar/{sup 40}Ar plateau ages near 65.0 Ma: these flows have unambiguously reversed magnetic polarity interpreted as chron 29R. As a preliminary summary, evidence of the KTB asteroid impact is confirmed in the Deccan traps, showing that they are coeval events in a general sense (in a Ma long window) though clearly with vastly different time constants. This is compatible with paleontologic evidence of two scales of extinctions, one quasi-instantaneous and the other on the order of 10{sup 5} to 10{sup 6} yrs. Clearly, the impact cannot have caused trap eruptions. On the other hand, the exact age and significance of the lower flows more altered remains to be analyzed further as they pertained to the much debated question of duration of Deccan trap volcanism. (author)

  2. "Ars Electronica 2009" / Raivo Kelomees

    Index Scriptorium Estoniae

    Kelomees, Raivo, 1960-

    2009-01-01

    30. "Ars Electronica" festival "Human Nature" ("Inimese loomus") Linzis. Osaka ülikooli professori Hiroshi Ishiguro mehaanilis-digitaalsest nukust. Hübriidkunsti kategoorias peapreemia saanud Eduardo Kaci inimtaimest. Konverentsidest. Näitusest "See this Sound", mis oli pühendatud helile kujutavas kunstis

  3. 40Ar-39Ar age clustering in the active phonolitic Cadamosto Seamount (Cape Verdes): Indications for periodic magmatic activity

    Science.gov (United States)

    Samrock, L. K.; Hansteen, T. H.; Wartho, J. A.

    2017-12-01

    The Cape Verde archipelago is situated 400-800 km off the west coast of Africa and is comprised of a northern and southern chain of islands and seamounts. Morphological observations and previous radiometric dating of the islands indicate a slow age progression, over 22 Ma, from east to west (Holm et al. 2008). We present the first radiometric ages for Cadamosto Seamount, which is composed of complex evolved volcanics and is situated at the southwestern tip of the Cape Verde archipelago (e.g. Barker et al. 2012). We analyzed five different submarine phonolites that were sampled by remotely operated vehicles (ROV) Kiel 6000 and dredging during the RV Meteor (M80/3) and RV Poseidon (POS320/2) cruises. Fresh sanidine, nepheline, and biotite grains were selected and carefully prepared for 40Ar-39Ar single grain total fusion analysis. Sanidine single grain 40Ar-39Ar ages from 5 samples range from 11.5 ± 6.5 ka to 349.0 ± 20.4 ka (2σ errors), and cluster in several age groupings (using the decay constant and atmospheric air ratio of Steiger & Jäger (1977), and age standard TCS2 (27.87 ± 0.04 Ma; 1σ; M.A. Lanphere, pers. comm.)). Three age groups can be identified within the youngest (0-170 ka) sanidines, which are separated by periods of 52-54 ka. Nepheline grains from one sample yielded much older ages of 169.5 ± 16.5 ka to 1521.5 ± 8.3 ka (2σ). Our data suggests young ages for the Cadamosto Seamount, which is in accordance with recorded seismic activity (Grevemeyer et al. 2010), and its position adjacent to the recently active islands of Fogo (last eruption in 2014/2015) and Brava (recent seismic activity). The different sub-groups of sanidine 40Ar-39Ar ages can be used to identify different activity maxima corresponding to cycles of magmatic productivity in a long-lived magmatic system. Ongoing petrologic investigations will be used to identify the relative importance of processes such as mantle melting rates, magma replenishment and magma chamber processes

  4. Cooling, exhumation, and deformation in the Hindu Kush, NW Pakistan: New constraints from preliminary 40Ar/39Ar and fission track analyses

    Science.gov (United States)

    Faisal, Shah; Larson, Kyle P.; Camacho, Alfredo; Coutand, Isabelle

    2018-06-01

    Asian crust in the Hindu Kush region in northern Pakistan records a protracted history of rifting, subduction and collision not commonly preserved within the Himalaya. Because of this, it is key to understanding the development of the southern Eurasian margin both prior to and after collision with India. New mica 40Ar/39Ar and apatite fission track geochronologic data from this region provide constraints on the kinematics of the Hindu Kush. 40Ar/39Ar muscovite and biotite ages from the late Cambrian Kafiristan pluton are 379.7 ± 1.7 Ma and 47.2 ± 0.3 Ma, respectively. The muscovite age may record cooling or partial resetting, while the biotite age is interpreted to record a thermal disruption associated with the early stages of continental collision in the Himalayan system. A 111.0 ± 0.6 Ma muscovite age from the northern part of the Tirich Mir pluton (∼123 Ma old; U-Pb) is interpreted to indicate a recrystallization event ∼12 Myrs after its intrusion. In addition, a younger muscovite age of 47.5 ± 0.2 Ma was derived from the opposite side of the same pluton in the immediate hanging wall of the Tirich Mir fault. This Eocene age is interpreted to represent the time of recrystallization during fault (re)activation in the early stages of India-Asia continent-continent collision. 40Ar/39Ar biotite analysis from the Buni-Zom pluton yields an age of 61.6 ± 1.1 Ma and is interpreted to reflect cooling at mid-upper crustal levels subsequent to the pluton's emplacement in the middle Cretaceous. Finally, 17.1-21.3 Ma 40Ar/39Ar ages from the Garam Chasma pluton and surrounding metapelites indicate cooling immediately following crystallization of the leucogranite body in the earliest Miocene/latest Oligocene. The younger cooling history is resolved by fission track dating of apatite (AFT). In the vicinity of the bounding Tirich Mir fault, the Tirich Mir pluton yields an AFT age of 1.4 ± 0.3 Ma, which is consistent with active exhumation associated with the surface

  5. ArControl: An Arduino-Based Comprehensive Behavioral Platform with Real-Time Performance.

    Science.gov (United States)

    Chen, Xinfeng; Li, Haohong

    2017-01-01

    Studying animal behavior in the lab requires reliable delivering stimulations and monitoring responses. We constructed a comprehensive behavioral platform (ArControl: Arduino Control Platform) that was an affordable, easy-to-use, high-performance solution combined software and hardware components. The hardware component was consisted of an Arduino UNO board and a simple drive circuit. As for software, the ArControl provided a stand-alone and intuitive GUI (graphical user interface) application that did not require users to master scripts. The experiment data were automatically recorded with the built in DAQ (data acquisition) function. The ArControl also allowed the behavioral schedule to be entirely stored in and operated on the Arduino chip. This made the ArControl a genuine, real-time system with high temporal resolution (<1 ms). We tested the ArControl, based on strict performance measurements and two mice behavioral experiments. The results showed that the ArControl was an adaptive and reliable system suitable for behavioral research.

  6. Uso de água residual do ar condicionado e de agua pluvial como gestão da oferta em uma edificação comercial: estudo de caso

    Directory of Open Access Journals (Sweden)

    Celso Silva Bastos

    2013-12-01

    Full Text Available O conceito do uso racional para a conservação de água consiste na gestão da demanda e da oferta de água, com ações voltadas para o fornecimento de fontes alternativas visando suprir o uso em áreas menos nobres por águas de qualidade inferior. Este trabalho tem por objetivo mostrar a aplicação de um sistema que aproveita a água drenada dos evaporadores de ar-condicionado e das águas pluviais como fontes alternativas. Verificou-se que cada evaporador produz 4,8 litros/água/hora, considerando 10 horas de uso diário, o volume acumulado chegaria a 48 litros/dia por aparelho que multiplicado pelo total de 137 unidades chega-se ao volume diário de 4.298 litros o que representa 77,72% da demanda das descargas sanitárias que é de 5.530 litros/dia. Em relação ao aproveitamento de águas pluviais, a previsão de acumulação refere-se a 10% da área do terreno que multiplicado pelo índice de 0,05 e pela retenção de 1 hora, obtém o volume de 14,8 m3 . Pretende-se com essa prática, alcançar uma redução significativa do volume de água potável, hoje utilizada praticamente para a realização de todas as atividades, contribuindo assim para uma obra mais sustentável, minimizando os impactos ambientais causados pela construção.

  7. Paleomagnetism and 40Ar / 39Ar Geochronology of Yemeni Oligocene volcanics: Implications for timing and duration of Afro-Arabian traps and geometry of the Oligocene paleomagnetic field

    Science.gov (United States)

    Riisager, Peter; Knight, Kim B.; Baker, Joel A.; Ukstins Peate, Ingrid; Al-Kadasi, Mohamed; Al-Subbary, Abdulkarim; Renne, Paul R.

    2005-09-01

    A combined paleomagnetic and 40Ar / 39Ar study was carried out along eight stratigraphically overlapping sections in the Oligocene Afro-Arabian flood volcanic province in Yemen (73 sites). The composite section covers the entire volcanic stratigraphy in the sampling region and represents five polarity zones that are correlated to the geomagnetic polarity time scale based on 40Ar / 39Ar ages from this and previous studies. The resulting magnetostratigraphy is similar to that of the conjugate margin in Ethiopia. The earliest basaltic volcanism took place in a reverse polarity chron that appears to correspond to C11r, while the massive rhyolitic ignimbrite eruptions correlated to ash layers in Oligocene Indian Ocean sediment 2700 km away from the Afro-Arabian traps, appear to have taken place during magnetochron C11n. The youngest ignimbrite was emplaced during magnetochron C9n. Both 40Ar / 39Ar and paleomagnetic data suggest rapid Red Sea. By analyzing Afro-Arabian paleomagnetic data in conjunction with contemporaneous paleomagnetic poles available from different latitudes we argue that the Oligocene paleomagnetic field was dominated by the axial dipole with insignificant non-dipole field contributions.

  8. Modification of van La ar activity coefficient model

    International Nuclear Information System (INIS)

    Vakili-Nezhaad, G. R.; Modarress, H.; Mansoori, G. A.

    2001-01-01

    Based on statistical and mechanical arguments, the original van La ar activity coefficient model has been improved by reasonable assumptions. This modifications has been done by replacing the van der Waals equation of state with the Redlich-K wong equation of state in the formulation of van La ar with consistent mixing rules for the energy and volume parameters of this equation of state (a mix , b mix ). Other equations of state, such as the Soave modification of the Redlich-K wong equation of state, P eng-Robinson and Mohsen-Nia, Modarress and Mansoori equations of state, have been introduced in the formulation of van La ar for the activity coefficients of the components present in the binary liquid mixtures, and their effects on the accuracy of the resultant activity coefficient models have been examined. The results of these revised models have been compared with the experimental data and it was found that the Redlich-K wong equation of state with the van der Waals mixing rules for the volume and energy parameters of this equation, is the best choice among these equations of state. In addition, it can improve the original van La ar activity coefficient model and, therefore a better agreement with the experimental data is obtained

  9. 77 FR 17363 - Proposed Establishment of Class E Airspace; West Memphis, AR

    Science.gov (United States)

    2012-03-26

    ...-0155; Airspace Docket No. 12-ASW-1] Proposed Establishment of Class E Airspace; West Memphis, AR AGENCY... action proposes to establish Class E airspace at West Memphis, AR. Separation of existing Class E... surface at West Memphis, AR, to accommodate the separation of existing Class E airspace surrounding West...

  10. Behaviour of AR glass fibre for building structural applications

    Directory of Open Access Journals (Sweden)

    Miravete, A.

    2005-12-01

    Full Text Available The AR glass reinforcement fibres were designed to resist the alkalis from the concrete. This is the main reason for its utilisation as a short-fibre-reinforcement of mortar and concrete for the last decades. Originally, the AR glass fibre sizing was not compatible with synthetic resins, so that this type of reinforcement was applied exclusively to mortar and concrete matrices. Recently, due to the developments of sizing, which are compatible with synthetic resins, the AR- glass fibres may be used as reinforcement of organic matrix composite materials, broadening the range of structural applications. The mechanical properties of AR glass fibre and organic matrix composite materials will be studied in this paper. First, the behaviour of this material under stress corrosion will be analysed. Their mass loss will be compared to E, C, and boron free glass fibres. Second, an experimental study dealing with 3P test bending and short beam ofAR glass fibre/polyester will de described with the goal of obtaining their Young modulus and tensile and interlaminar shear strengths. Finally, these experimental results will be compared to E glass fibre/polyester and several conclusions about their structural applications will be drawn.

    El vidrio AR y su presentación en forma de fibras de refuerzo, fue diseñado para ser inerte a los álcalis de los cementos. Por este motivo se viene utilizando desde hace varias décadas como refuerzo de morteros y hormigones en forma de fibra corta. El ensimaje que estas fibras de vidrio de refuerzo A R presentaba en su origen no era compatible con resinas de tipo sintéticas, por lo que el refuerzo era exclusivo para cementos y hormigones fuera cual fuera la aplicación, formato o proceso productivo. Recientemente, gracias al desarrollo específico de ensimajes especiales acordes a las fibras de vidrio AR ha aparecido la misma tipología de vidrio AR como refuerzo en forma de fibra continua compatible con resinas sint

  11. Numerical simualtion of underground 37Ar transportation to the ground

    International Nuclear Information System (INIS)

    She Ruogu; Li Hua; Liu Cheng'an; Wu Jun

    2008-01-01

    Monitoring radioactive gas 37 Ar is an important technique for the On-Site Inspection(OSI) of the Comprehensive Nuclear Test Ban Treaty (CTBT) verification regime. In order to establish a theoretical model that can be used to calculate the appearing time and radioactivity of 37 Ar which transports to the ground after a nuclear explosion, the rock media in the test area is assumed to be a homogeneous porous media, without consideration of gas absorption by and release from the rock media. The seepage model in the porous media is used to calculate 37 Ar transportation. Computational results give the time 37 Ar leaks to the ground and the variation of its radioactivity with time. And we can analyze and consider the computational results when we have developed OSI noble gas monitoring systems and evaluated their effectiveness. (authors)

  12. Adesão ao tratamento no transtorno bipolar

    OpenAIRE

    Santin,Aida; Ceresér,Keila; Rosa,Adriane

    2005-01-01

    O transtorno bipolar (TB) é uma doença crônica, recorrente, presente em 1,5% da população, estando associada a altas taxas de mortalidade e prejuízos socioeconômicos. O lítio, a carbamazepina e o ácido valpróico são os estabilizadores de humor mais usados. Em tratamentos prolongados, como é o caso do TB, a má-adesão dos pacientes é uma das maiores dificuldades. Verifica-se que fatores ligados ao paciente, aos medicamentos e aos médicos possam ser responsáveis pela baixa adesão. A psicoeducaçã...

  13. CERN inspires 2011 edition of the ARS Electronica Digital Arts Festival

    CERN Multimedia

    Jordan Juras

    2011-01-01

    This year’s annual ARS Electronica Digital Arts Festival featured CERN as the springboard for its theme, ORIGIN – How it All Begins. The prestigious digital arts festival also served as the perfect venue to launch the Collide@CERN project.   Colours and Lights at the ARS Electronica Digital Arts Festival in Linz (Austria). (Photo by Claudia Marcelloni) The CERN cultural policy project, announced at the beginning of 2011 has started to gain momentum. Ariane Koek, art specialist for the Communication Group, received confirmation in May that ARS Electronica had chosen her proposal to use CERN as the primary source of inspiration for their annual ARS Electronica Festival. This marks the first of the cultural policy’s arts partnerships. The world-renowned celebration for the digital arts is held annually in Linz, Austria, where, amongst the incredible collection of displays and productions, the Prix ARS Electronica – the Oscars of the digital arts world -&...

  14. The role of the AR/ER ratio in ER-positive breast cancer patients.

    Science.gov (United States)

    Rangel, Nelson; Rondon-Lagos, Milena; Annaratone, Laura; Osella-Abate, Simona; Metovic, Jasna; Mano, Maria Piera; Bertero, Luca; Cassoni, Paola; Sapino, Anna; Castellano, Isabella

    2018-03-01

    The significance of androgen receptor (AR) in breast cancer (BC) management is not fully defined, and it is still ambiguous how the level of AR expression influences oestrogen receptor-positive (ER+) tumours. The aim of the present study was to analyse the prognostic impact of AR/ER ratio, evaluated by immunohistochemistry (IHC), correlating this value with clinical, pathological and molecular characteristics. We retrospectively selected a cohort of 402 ER+BC patients. On each tumour, IHC analyses for AR, ER, PgR, HER2 and Ki67 were performed and AR+ cases were used to calculate the AR/ER value. A cut-off of ≥2 was selected using receiver-operating characteristic (ROC) curve analyses. RNA from 19 cases with AR/ER≥2 was extracted and used for Prosigna-PAM50 assays. Tumours with AR/ER≥2 (6%) showed more frequent metastatic lymph nodes, larger size, higher histological grade and lower PgR levels than cases with AR/ERAR/ER≥2 had worse disease-free interval (DFI) and disease-specific survival (DSS) (hazard ratios (HR) = 4.96 for DFI and HR = 8.69 for DSS, both P  ≤ 0.004). According to the Prosigna-PAM50 assay, 63% (12/19) of these cases resulted in intermediate or high risk of recurrence categories. Additionally, although all samples were positive for ER assessed by IHC, the molecular test assigned 47.4% (9/19) of BCs to intrinsic non-luminal subtypes. In conclusion, the AR/ER ratio ≥2 identifies a subgroup of patients with aggressive biological features and may represent an additional independent marker of worse BC prognosis. Moreover, the Prosigna-PAM50 results indicate that a significant number of cases with AR/ER≥2 could be non-luminal tumours. © 2018 Society for Endocrinology.

  15. An analysis of the 1977 AD/AR TARSLL.

    OpenAIRE

    Hargrove, James Wiley Jr.

    1980-01-01

    Approved for public release; distribution is unlimited The industrial mission of Destroyer Tenders (AD) and Repair Ships (AR) is to provide intermediate level maintenance and repair for supported ships. The Tender and Repair Ship Load List for these ships (AD/AR TARSLL) designates the range (number) and depth (quantity) of repair parts to be carried to support this industrial mission. This thesis details the logical reasoning and mathematical theory used to develop the...

  16. ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells

    International Nuclear Information System (INIS)

    Komaragiri, Shravan Kumar; Bostanthirige, Dhanushka H.; Morton, Derrick J.; Patel, Divya; Joshi, Jugal; Upadhyay, Sunil; Chaudhary, Jaideep

    2016-01-01

    Deregulation of tumor suppressor genes is associated with tumorigenesis and the development of cancer. In prostate cancer, ID4 is epigenetically silenced and acts as a tumor suppressor. In normal prostate epithelial cells, ID4 collaborates with androgen receptor (AR) and p53 to exert its tumor suppressor activity. Previous studies have shown that ID4 promotes tumor suppressive function of AR whereas loss of ID4 results in tumor promoter activity of AR. Previous study from our lab showed that ectopic ID4 expression in DU145 attenuates proliferation and promotes AR expression suggesting that ID4 dependent AR activity is tumor suppressive. In this study, we examined the effect of ectopic expression of ID4 on highly malignant prostate cancer cell, PC3. Here we show that stable overexpression of ID4 in PC3 cells leads to increased apoptosis and decreased cell proliferation and migration. In addition, in vivo studies showed a decrease in tumor size and volume of ID4 overexpressing PC3 cells, in nude mice. At the molecular level, these changes were associated with increased androgen receptor (AR), p21, and AR dependent FKBP51 expression. At the mechanistic level, ID4 may regulate the expression or function of AR through specific but yet unknown AR co-regulators that may determine the final outcome of AR function. - Highlights: • ID4 expression induces AR expression in PC3 cells, which generally lack AR. • ID4 expression increased apoptosis and decreased cell proliferation and invasion. • Overexpression of ID4 reduces tumor growth of subcutaneous xenografts in vivo. • ID4 induces p21 and FKBP51 expression- co-factors of AR tumor suppressor activity.

  17. ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Komaragiri, Shravan Kumar; Bostanthirige, Dhanushka H.; Morton, Derrick J.; Patel, Divya; Joshi, Jugal; Upadhyay, Sunil; Chaudhary, Jaideep, E-mail: jchaudhary@cau.edu

    2016-09-09

    Deregulation of tumor suppressor genes is associated with tumorigenesis and the development of cancer. In prostate cancer, ID4 is epigenetically silenced and acts as a tumor suppressor. In normal prostate epithelial cells, ID4 collaborates with androgen receptor (AR) and p53 to exert its tumor suppressor activity. Previous studies have shown that ID4 promotes tumor suppressive function of AR whereas loss of ID4 results in tumor promoter activity of AR. Previous study from our lab showed that ectopic ID4 expression in DU145 attenuates proliferation and promotes AR expression suggesting that ID4 dependent AR activity is tumor suppressive. In this study, we examined the effect of ectopic expression of ID4 on highly malignant prostate cancer cell, PC3. Here we show that stable overexpression of ID4 in PC3 cells leads to increased apoptosis and decreased cell proliferation and migration. In addition, in vivo studies showed a decrease in tumor size and volume of ID4 overexpressing PC3 cells, in nude mice. At the molecular level, these changes were associated with increased androgen receptor (AR), p21, and AR dependent FKBP51 expression. At the mechanistic level, ID4 may regulate the expression or function of AR through specific but yet unknown AR co-regulators that may determine the final outcome of AR function. - Highlights: • ID4 expression induces AR expression in PC3 cells, which generally lack AR. • ID4 expression increased apoptosis and decreased cell proliferation and invasion. • Overexpression of ID4 reduces tumor growth of subcutaneous xenografts in vivo. • ID4 induces p21 and FKBP51 expression- co-factors of AR tumor suppressor activity.

  18. Bartlett correction in the stable AR(1) model with intercept and trend

    NARCIS (Netherlands)

    van Giersbergen, N.P.A.

    2004-01-01

    The Bartlett correction is derived for testing hypotheses about the autoregressive parameter ρ in the stable: (i) AR(1) model; (ii) AR(1) model with intercept; (iii) AR(1) model with intercept and linear trend. The correction is found explicitly as a function of ρ. In the models with deterministic

  19. Comparison of Ne and Ar seeded radiative divertor plasmas in JT-60U

    Energy Technology Data Exchange (ETDEWEB)

    Nakano, T., E-mail: nakano.tomohide@jaea.go.jp

    2015-08-15

    In H-mode plasmas with Ne, Ar and a mixture of Ne and Ar injection, the divertor radiation power fractions amongst these impurities in addition to an intrinsic impurity, C, are investigated. In plasmas with the inner divertor plasma attached, carbon is the biggest radiator, whichever impurity, Ne, Ar or a mixture of Ar and Ne is injected. In contrast, in plasmas with the inner divertor plasma detached, Ne is the biggest radiator due to a significantly high recombination radiation from Ne VIII. Ar is always a minor contributor in plasmas with the inner divertor both attached and detached.

  20. Uma análise da correlação entre o EVA® e o MVA® no contexto das empresas brasileiras de capital aberto Correlation between Economic Value Added and Market Value Added for publicly owned Brazilian companies

    Directory of Open Access Journals (Sweden)

    José Odálio dos Santos

    2005-03-01

    Full Text Available Este artigo trata do tema da criação de valor, da forma como é medida pelo EVA® (Valor Econômico Adicionado e pelo MVA® (Valor de Mercado Agregado, duas metodologias desenvolvidas no final dos anos 80 pela empresa americana de consultoria Stern Stewart & Co. O EVA® é definido como a diferença entre o lucro operacional líquido depois de impostos e o custo do capital investido na empresa, enquanto o MVA® é determinado pela diferença entre o valor de mercado da empresa e o capital total nela investido. Um estudo realizado por G. Bennett Stewart III, que idealizou essas metodologias juntamente com o seu sócio Joel M. Stern, encontrou uma forte correlação entre o EVA® e o MVA®. Visando averiguar se tal resultado se aplica também ao caso das empresas brasileiras, os autores deste artigo realizaram uma pesquisa semelhante, baseada numa amostra formada por empresas de capital aberto cujas ações foram negociadas na Bovespa (Bolsa de Valores de São Paulo durante o período de 1996 a 2001.This article deals with value creation as measured by Economic Value Added (EVA® and Market Value (MVA® which are methods developed by an American consultant, Stern Stewart & Co, in the late l980's. Economic Value Added is defined as the difference between net operating profit after taxes and the cost of capital invested in a company, while Market Value Added is the difference between market value and the total capital invested in a company. G. Bennett Stewart III, who conceived this approach together with his partner Joel M. Stern, found a strong correlation between Economic Value Added and Market Value Added. Our research investigated whether this also applies to a sample of publicly owned Brazilian companies traded on the São Paulo Stock Exchange between 1996 and 2001.

  1. DA IDEAÇÃO AO ROADSHOW: UMA EXPERIÊNCIA PEDAGÓGICA INTERDISCIPLINAR

    Directory of Open Access Journals (Sweden)

    Sílvio Luiz de Paula

    2017-02-01

    Full Text Available O objetivo deste trabalho é descrever uma prática pedagógica, inserida no bojo das metodologias ativas, que leva em consideração a interdisciplinaridade, o desenvolvimento de competências e uma avaliação centrada no processo. Para tanto, ao buscar ampliar o entendimento sobre metodologias ativas e dar intelecção sobre as bases que deram suporte a experiência, no embasamento teórico discute-se sobre interdisciplinaridade, desenvolvimento de competências e avaliação de aprendizagem. Na metodologia, visando a alcançar o entendimento da prática realizada, além dos registros programados realizados pelos três professores envolvidos na condução da atividade, aplicaram-se questionários com os alunos durante o processo, realizando-se ao final um grupo focal. A prática, realizada no segundo semestre letivo de 2016, contou com a participação de aproximadamente 90 alunos dos cursos de Administração e Gestão da Informação da Universidade Federal de Pernambuco (UFPE que, por meio da modelagem Canvas, método utilizado na fase de ideação para a criação dos novos empreendimentos, desenvolveram sete empresas inovadoras e criativas, finalizando o semestre com a apresentação das empresas no formato de roadshow, forma de apresentação utilizada em ambiente de startup nas rodadas de negócios para captação de investimentos. Como principais achados identifica-se a importância de experiências interdisciplinares que conduzam os alunos a vivenciarem situações que possibilitem o desenvolvimento de competências para além dos conteúdos curriculares. Da perspectiva dos docentes envolvidos ressaltam-se os desafios na formação para a condução de tais práticas, bem como as dificuldades da estrutura e modelo pedagógico adotado na instituição.

  2. Essential Characteristics of Plasma Antennas Filled with He-Ar Penning Gases

    International Nuclear Information System (INIS)

    Sun Naifeng; Li Wenzhong; Wang Shiqing; Li Jian; Ci Jiaxiang

    2012-01-01

    Based on the essential theory of Penning gases, the discharge characteristics of He-Ar Penning gases in insulating tubes were analyzed qualitatively. The relation between the effective length of an antenna column filled with He-Ar Penning gases and the applied radio frequency (RF) power was investigated both theoretically and experimentally. The distribution of the plasma density along the antenna column in different conditions was studied. The receiving characteristics of local frequency modulated (FM) electromagnetic waves by the plasma antenna filled with He-Ar Penning gases were compared with those by an aluminum antenna with the same dimensions. Results show that it is feasible to take plasma antennas filled with He-Ar Penning gases as receiving antennas.

  3. Recoil ion charge state distributions in low energy Arq+ - Ar collisions

    International Nuclear Information System (INIS)

    Vancura, J.; Marchetti, V.; Kostroun, V.O.

    1992-01-01

    We have measured the recoil ion charge state distributions in Ar q+ -- Ar (8≤q≤16) collisions at 2.3 qkeV and 0.18qkeV by time of flight (TOF) spectroscopy. For Ar 8-16+ , recoil ion charge states up to 6+ are clearly present, indicating that the 3p subshell in the target atom is being depleted, while for Ar 10-16+ , there is evidence that target 3s electrons are also being removed. Comparison of the recoil ion charge state spectra at 2.3 and 0.18 qkeV shows that for a given projectile charge, there is very little dependence of the observed recoil target charge state distribution on projectile energy

  4. Electron transfer from H2 and Ar to stored multiply charged argon ions produced by synchrotron radiation

    International Nuclear Information System (INIS)

    Kravis, S.D.; Church, D.A.; Johnson, B.M.; Meron, M.; Jones, K.W.; Levin, J.C.; Sellin, I.A.; Azuma, Y.; Berrah-Mansour, N.; Berry, H.G.; Druetta, M.

    1992-01-01

    The rate coefficients for electron transfer from Ar and H 2 to Ar q+ ions (3≤q≤6) have been measured using an ion-storage technique in a Penning ion trap. The ions were produced in the trap by K-shell photoionization of Ar atoms, using broadband synchrotron x-ray radiation. K-electron removal resulted in vacancy cascading, yielding a distribution of argon-ion charge states peaked near Ar 4+ . The stored ion gas had an initial temperature near 480 K. The basic data determining the rate coefficients k(Ar q+ ) are the storage time constants of each charge state in the trap, in the presence of a measured pressure of target gas. The results of the measurements (in units of 10 -9 cm 3 s -1 ) are k(Ar 3+ ,H 2 )=4.3(0.7), k(Ar 3+ ,Ar)=1.6(0.2), k(Ar 4+ ,H 2 )=5.2(0.6), k(Ar 4+ ,Ar)=2.5(0.3), k(Ar 5+ ,H 2 )=5.9(0.7), k(Ar 5+ ,Ar)=2.9(0.3), k(Ar 6+ ,H 2 )=8.5(1.2), and k(Ar 6+ ,Ar)=2.5(0.3)

  5. Testing of a prototype of calibration facility for noble gas monitoring using 41Ar

    International Nuclear Information System (INIS)

    Saibathulham, Holnisar; Wurdiyanto, Gatot; Marsum, Pujadi

    2012-01-01

    A prototype of a calibration facility for noble gas monitoring using 41 Ar in the PTKMR-BATAN has been tested. The facility was designed in such a way that the standard source of gas can be reused. The radioactive 41 Ar source was obtained by thermal neutron reaction of 40 Ar(n, γ) 41 Ar using a thermal neutron flux of 4.8×10 13 neutrons per cm 2 per second in two minutes on the multipurpose G.A. Siwabessy Reactor (Batan, Serpong, Indonesia). Gamma spectrometry was used to measure the radioactivity and purity of 41 Ar. The spectrum of the 41 Ar observed yields an energy of 1294 keV because of the highest intensity (99.2%). The activity of 41 Ar was 2821 kBq and 4% of the expanded uncertainty. The time required for 41 Ar to reach homogeneity was 7 min, and the effectiveness of resuse was 53%. - Highlights: ► Testing of a calibration facility prototype for noble gas monitor using 41 Ar in PTKMR-BATAN. ► This facility was designed such that a standard radioactive gas source can be used repeatedly. ► Standardization of the 41 Ar is performed using gamma spectrometry. ► The time required for the 41 Ar gas to be distributed evenly throughout the cavity of the facility was 7 min. ► The effectiveness of repeated use was 53%.

  6. In-situ 40Ar/39Ar Laser Probe Dating of Micas from Mae Ping Shear Zone, Northern Thailand

    Science.gov (United States)

    Lin, Y. L.; Yeh, M. W.; Lo, C. H.; Lee, T. Y.; Charusiri, P.

    2012-04-01

    The Mae Ping Shear Zone (MPSZ, also known as Wang Chao Fault Zone), which trends NW-SE from Myanmar to central Thailand, was considered as the southern boundary of the SE extrusion of Indochina and Sibumasu block during the Cenozoic escape tectonic event of SE asia. Many analyses of 40Ar/39Ar dating on biotite and K-feldspar, K/Ar dating on biotite and illite, zircon fission-track and apatite fission-track dating had been accomplished to constrain the shearing period. Nevertheless, it is hard to convince that the ages could represent the end of the shearing since none of the dated minerals have been proved to be crystallized syn-tectonically. Meta-granitoid and gneiss from the MPSZ were analyzed in this study by applying in-situ 40Ar/39Ar laser probe dating with combination of petrology and micro-structural analysis in the purpose to decipher the geological significance of the dates. Plagioclase was replacing K-feldspar for K-feldspar was cut and embayed by plagioclase observed by SEM + EDS. Muscovite in the granitoid own fish shapes of sinistral sense of shearing, and are always in contact with plagioclase and quartz, which suggests that the muscovite crystallized from the dissolving K-feldspar under amphibolite facies condition. 117 spots on 12 muscovite fishes yield ages from 44 Ma to 35 Ma and have a mean age of 40 Ma. Since the growth condition of the muscovite is higher than the closure temperature, thus we can interpret these muscovite ages as cooling ages. Hence left-lateral shearing of the MPSZ can be deduced as syn- to post-muscovite growth and uplifted the crystalline rocks within the shear zone. The ages of matrix biotite in gneiss has a mean age of 35 Ma, which is consistent with the cooling path reconstructed from previous studies. While the ages of inclusion biotite in the K-feldspar phenocryst scatter from 40 to 50 Ma due to the isotopes were not totally re-equilibrated during the shearing. Consequently, the left-lateral shearing of the MPSZ was

  7. Microstructural finite strain analysis and 40Ar/39Ar evidence for the origin of the Mizil gneiss dome, eastern Arabian Shield, Saudi Arabia

    Science.gov (United States)

    Al-Saleh, Ahmad M.; Kassem, Osama M. K.

    2012-07-01

    The Mizil antiform is a gneiss-cored culmination situated near the northern end of the Ar Rayn island arc terrane, which is the easternmost exposed tectonic unit of the Arabian Shield. This domal structure has a mantle of metamorphosed volcanosedimentary rocks belonging to the Al-Amar Group, and an igneous interior made up of foliated granodiorite-tonalite with adakitic affinity. The gneissic core has a SHRIMP U-Pb zircon age of 689 ± 10 Ma making it the oldest rock unit in the Ar Rayn terrane. An adakite diapir, formed by the melting of the subducted crust of a young marginal basin, and rising through the volcanosedimentary succession of the Ar Rayn island arc is thought to have caused the observed doming. Relatively uniform strain throughout the dome combined with strong vertical shortening and the roughly radial pattern of stretching lineation is consistent with diapirism; the absence of strain localization rules out detachment faulting as a causative mechanism. Amphibolites from the metamorphic envelope have an 40Ar/39Ar age of 615 ± 2 Ma; the age gap between core and cover is thought to reflect the resetting of metamorphic ages during the final suturing event, a phenomenon that is often observed throughout the eastern shield. Aeromagnetic anomalies beneath the Phanerozoic sedimentary cover indicate the presence of a collage of accreted terranes east of the Ar Rayn terrane that were probably amalgamated onto the Arabian margin during the latest stages of the closure of the Mozambique ocean; culminant orogeny is believed to have taken place between 620 and 600 Ma as these terrane collided with a major continental mass to the east referred to here as the eastern Arabian block (EAB). The Mizil gneiss dome is therefore considered to have formed in a convergent contractional setting rather than being the outcome of extensional post-orogenic collapse.

  8. Atmospheric pressure plasma jet utilizing Ar and Ar/H2O mixtures and its applications to bacteria inactivation

    International Nuclear Information System (INIS)

    Cheng Cheng; Shen Jie; Xiao De-Zhi; Xie Hong-Bing; Lan Yan; Fang Shi-Dong; Meng Yue-Dong; Chu Paul K

    2014-01-01

    An atmospheric pressure plasma jet generated with Ar with H 2 O vapor is characterized and applied to inactivation of Bacillus subtilis spores. The emission spectra obtained from Ar/H 2 O plasma shows a higher intensity of OH radicals compared to pure argon at a specified H 2 O concentration. The gas temperature is estimated by comparing the simulated spectra of the OH band with experimental spectra. The excitation electron temperature is determined from the Boltzmann's plots and Stark broadening of the hydrogen Balmer H β line is applied to measure the electron density. The gas temperature, excitation electron temperature, and electron density of the plasma jet decrease with the increase of water vapor concentration at a fixed input voltage. The bacteria inactivation rate increases with the increase of OH generation reaching a maximum reduction at 2.6% (v/v) water vapor. Our results also show that the OH radicals generated by the Ar/H 2 O plasma jet only makes a limited contribution to spore inactivation and the shape change of the spores before and after plasma irradiation is discussed. (physics of gases, plasmas, and electric discharges)

  9. Age intercalibration of 40Ar/39Ar sanidine and chemically distinct U/Pb zircon populations from the Alder Creek Rhyolite Quaternary geochronology standard

    DEFF Research Database (Denmark)

    Rivera, Tiffany; Storey, Michael; Schmitz, M. D.

    2013-01-01

    , and have less pronounced positive Ce and negative Eu anomalies, lower incompatible trace element contents, higher TiZR temperatures that range up to 840 °C, and significantly younger dates. The youngest Group A dates yield a weighted mean of 1.1978 ± 0.0046 Ma (2σ, including systematic uncertainties...... with the astronomical age estimate for the Cobb Mountain subchron determined by correlating the oxygen isotope record of the giant piston core MD972143 to the La93(1,1) orbital solution. On the basis of independent radio-isotopic and orbital forcing results, we propose the refined age of 1.1850 ± 0.0016 Ma (2σ external......We report results from a 40Ar/39Ar sanidine and CA-TIMS 238U/206Pb zircon dating study of eruption and crystal residence timescales of the Alder Creek Rhyolite (ACR), California, extruded during the Cobb Mountain normal-polarity subchron (C1r.2n). A 40Ar/39Ar ACR sanidine date of 1.1850 ± 0.0016 Ma...

  10. Geochronological {sup 40}Ar/{sup 39}Ar data on the submarine fault-scarps in the Sardinia channel (western mediterranean); Donnees geochronologiques {sup 40}Ar/{sup 39}Ar sur les socles sarde et kabylo-peloritain submerges dans le canal de Sardaigne (mediterranee occidentale)

    Energy Technology Data Exchange (ETDEWEB)

    Bouillin, J.P.; Tricart, P.; Mascle, G. [Grenoble-1 Univ., 38 - Grenoble (France). Laboratoire de Geodynamique des Chaines Alpines, CNRS UPRES-A5025; Monie, P. [Montpellier-2 Univ., 34 (France). Laboratoire de Geochronologie, Geochimie et de petrologie, UMR 5567; Rolfo, F. [Universita Torino, (Italy). Dipt. di Scienze Mineralogiche et Petrologiche; Torelli, L. [Parma Univ. (Italy). Ditp. di Scienze della Terra

    1999-04-01

    Granite and gneiss have been sampled on the submarine fault scarps of the Sardinia Channel and have been dated using the {sup 40}Ar/{sup 39}Ar method. The majority of rocks partially preserve Hercynian ages. Some of them display Lower Cretaceous ages. In addition, Upper Eocene-Oligocene argon resetting is recorded only in rocks from the southeast sector of the Channel. We thus propose that the basement of the Sardinia Channel occupied a shallow position within the stack of the Alpine tectonic units, behind the more deformed front of the internal zones of the Maghrebide Chain. (authors) 20 refs.

  11. The 40Ar-39Ar dating of the metasomatites in the deep-fault zones of margin suture system of Siberian platform

    International Nuclear Information System (INIS)

    Savel'eva, V.B.; Travin, A.V.; Zyryanov, A.S.

    2003-01-01

    For clarifying the time sequence of metasomatites formation of diverse geochemical types in deep-fault zones of margin suture system of Siberian platform the 40 Ar- 39 Ar-isotope dating of their rock-forming minerals was performed. It was ascertained that formation of major metasomatic formations in the Baikal and Sayan branches of the margin suture system of Siberian platform was asynchronous, the time lag being in excess of 100 bl. years [ru

  12. Experimental Determination of the Cosmogenic Ar Production Rate From Ca

    Science.gov (United States)

    Niedermann, S.; Schäfer, J. M.; Wieler, R.; Naumann, R.

    2005-12-01

    Cosmogenic 38Ar is produced in terrestrial surface rocks by spallation of target nuclides, in particular K and Ca. Though the presence of cosmogenic Ar in Ca-rich minerals has been demonstrated earlier [1], is has proven difficult to establish its production rate. To circumvent problems connected to 36Ar production by 35Cl neutron capture and different production rates from K and Ca, we have analyzed the noble gases in seven pyroxene separates (px) from the Antarctic Dry Valleys which are essentially free of Cl and K. The px were obtained from dolerite rocks, for which 3He and 21Ne exposure ages from 1.5 to 6.5 Ma have been reported [2]. The noble gases were extracted in two or three heating steps at GFZ Potsdam, yielding 38Ar/36Ar ratios up to 0.2283 ± 0.0008 (air: 0.1880). Ca (3.7-11.2 wt. %) is expected to be the only relevant target element for Ar production in the five pure px (ratio of 1.5 ± 0.2, we obtain cosmogenic 38Ar concentrations between 130 and 530x106 atoms/g. The 38Ar production rate was calculated based on 21Ne exposure ages [2], corrected for elevated nuclide production in Antarctica due to prevailing low air pressure and for the revised 21Ne production rate from Si. We obtain values between 188 ± 17 and 243 +110/-24 atoms (g Ca)-1 a-1 at sea level and high (northern) latitudes for four out of the five pure px, while one yields a very high value of 348 ± 70 atoms (g Ca)-1 a-1. Values above 250 atoms (g Ca)-1 a-1 are also obtained from two less pure px containing 0.3 and 0.9% K and from one feldspar/quartz accumulate, indicating that the production rate from K may be higher than that from Ca. The weighted mean (excluding the outlier) of ~200 atoms (g Ca)-1 a-1 is in excellent agreement with Lal's [3] theoretical estimate. [1] Renne et al., EPSL 188 (2001) 435. [2] Schäfer et al., EPSL 167 (1999) 215. [3] Lal, EPSL 104 (1991) 424.

  13. Precision angle-resolved autoionization resonances in Ar and Ne

    Energy Technology Data Exchange (ETDEWEB)

    Berrah, N.; Langer, B.; Gorczyca, T.W. [Western Michigan Univ., Kalamazoo, MI (United States)] [and others

    1997-04-01

    Theoretical work has shown that the electron angular distribution and the shape of the autoionization resonances are crucial to the understanding of certain types of electron-electron correlation. Autoionization resonances in Ne (Ar) result from the decay of the excited discrete state Ne{sup *} 2s2p{sup 6} np (Ar{sup *} 3s3p{sup 6} np) into the continuum state Ne{sup +} 2s{sup 2}2p{sup 5} + e{sup {minus}} (ks,kd) (Ar{sup +} 3s{sup 2}3p{sup 5} + e{sup {minus}} (ks,kd)). Since the continuum can also be reached by direct photoionization, both paths add coherently, giving rise to interferences that produce the characteristic Beutler-Fano line shape. In this work, the authors report on quantitative angle-resolved electron spectrometry studies of (a) the Ne 2s{sup 2}2p{sup 6} {r_arrow} 2s2p{sup 6} np (n=3-5) autoionizing resonances and the 2s{sup 2}2p{sup 6} {r_arrow} 2p{sup 4}3s3p doubly excited resonance, (b) the Ar 3s{sup 2}3p{sup 6} {r_arrow} 3s3p{sup 6} np (n=4-9) autoionization resonances and extended R-matrix calculations of the angular-distribution parameters for both Ne and Ar measurements. Their results are compared with previous theoretical work by Taylor.

  14. O direito fundamental ao conteúdo do próprio trabalho: uma reconstrução normativa do direito ao trabalho

    Directory of Open Access Journals (Sweden)

    Leonardo Vieira Wandelli

    2016-12-01

    Full Text Available Resumo: Pretende-se enfrentar a inefetividade do direito humano e fundamental ao trabalho a partir de um esforço de reconstrução normativa da sua fundamentação, apoiada em um duplo pilar teórico, nas teorias das necessidades e nas teorias do reconhecimento. Com isso, não somente se recupera a importância do vínculo entre trabalho e dignidade humana, como se explicitam aspectos essenciais da centralidade do trabalho para os sujeitos. A partir disso, o direito ao trabalho se desvela não apenas como necessidade radical, tendente à transformação da institucionalidade vigente, mas também como direito positivado em um amplo leque de normas internacionais e nacionais, que contempla diversas dimensões normativas atualmente exigíveis. Propõe-se que, no centro desse direito, está um direito fundamental ao conteúdo do próprio trabalho, que determina juridicamente as condições da atividade e da organização do trabalho. Recente estudo adotado pelo Alto Comissariado em Direitos Humanos da Organização das Nações Unidas (ONU sobre o direito ao trabalho reforça essa compreensão. Palavras-chave: Direitos humanos. Direitos fundamentais. Direito ao trabalho. Psicodinâmica do trabalho. Direito do trabalho.

  15. Effects of antibiotic resistance (AR) and microbiota shifts on Campylobacter jejuni-mediated diseases.

    Science.gov (United States)

    Brooks, Phillip T; Mansfield, Linda S

    2017-12-01

    Campylobacter jejuni is an important zoonotic pathogen recently designated a serious antimicrobial resistant (AR) threat. While most patients with C. jejuni experience hemorrhagic colitis, serious autoimmune conditions can follow including inflammatory bowel disease (IBD) and the acute neuropathy Guillain Barré Syndrome (GBS). This review examines inter-relationships among factors mediating C. jejuni diarrheal versus autoimmune disease especially AR C. jejuni and microbiome shifts. Because both susceptible and AR C. jejuni are acquired from animals or their products, we consider their role in harboring strains. Inter-relationships among factors mediating C. jejuni colonization, diarrheal and autoimmune disease include C. jejuni virulence factors and AR, the enteric microbiome, and host responses. Because AR C. jejuni have been suggested to affect the severity of disease, length of infections and propensity to develop GBS, it is important to understand how these interactions occur when strains are under selection by antimicrobials. More work is needed to elucidate host-pathogen interactions of AR C. jejuni compared with susceptible strains and how AR C. jejuni are maintained and evolve in animal reservoirs and the extent of transmission to humans. These knowledge gaps impair the development of effective strategies to prevent the emergence of AR C. jejuni in reservoir species and human populations.

  16. ARS 01 Helsingi Kiasmas / Tarmo Virki

    Index Scriptorium Estoniae

    Virki, Tarmo

    2001-01-01

    Helsingis Kiasmas avatud rahvusvahelisest kunstinäitusest ARS 01 alapealkirjaga "Avanevaid perspektiive", kus esines oma töödega ka Marko Mäetamm. Näituse raames toimuvast Santiago Sierra kunstiprojektist kodututega

  17. 40Ar/39Ar Geochronology of Supergene K-bearing Sulfate Minerals: Cenozoic Continental Weathering, Landscape Evolution and Paleoclimates in the Tu-Ha Basin, Northwestern China

    Science.gov (United States)

    Yang, J.; Zheng, D.; Chen, W.; Hough, B.; Qiu, H.; Wang, W.; Wu, Y.; Yang, L.

    2017-12-01

    40Ar/39Ar incremental-heating analyses of supergene jarosite and yavapaiite from three weathering profiles at the Hongshan, Liuhuangshan, and Caihuagou deposits in the Tu-Ha Basin, China, were carried out to provide numerical constraints on the timing and duration of weathering and derive insights into local paleoclimatic and landscape evolution. Well-constrained plateau ages and best-fitting inverse isochrons have been obtained for 11 samples, yield 40Ar/39Ar ages ranging from 33.3±0.5 Ma to 3.3±0.4 Ma (1σ). Our 40Ar/39Ar ages, combined with the published ages, indicate that the high elevations sites hosting the most complete and complex weathering profiles present. The presence of ancient weathering ages in current outcrop in the Tu-Ha Basin suggests that denudation was not homogeneous, and the landscape evolution follow a scarp retreat model. These geochronological results suggest that a protracted history of weathering and supergene enrichment and, by inference, arid-semiarid climate (with at least a moderate amount of precipitation (>10 cm/y)) favorable to intense chemical weathering emerged at 33.3 Ma, 27.7-23.3 Ma, and 16.4-14.7 Ma, and prevailed from 11-7.8 Ma. Then, a progressive change from arid-semiarid towards hyperarid conditions and predominantly hyperarid conditions may have persisted since at least ca. 3.3 Ma. The climatic implications inferred from the weathering geochronology are in agreement with the chemical parameters and isotopic compositions of the Cenozoic sedimentary sequence from the Lianmuqin section in the Tu-Ha Basin, attesting to the reliability of weathering geochronology by the 40Ar/39Ar method as an indicator of paleoclimate in arid areas. Our results suggest that the retreat of the Paratethys Sea, which would have reduced eastward water vapor transport by the westerlies to the Tu-Ha Basin, led to its aridification in the Oligocene and that increased rain shadow effects, resulting from uplift of the Tibetan Plateau and Tian Shan

  18. The total collision cross section of Ar-Ar as a function of velocity in the thermal range

    International Nuclear Information System (INIS)

    Linse, C.A.; Biesen, J.J.H. van den; Meijdenberg, C.J.N. van den

    1977-01-01

    To describe the Ar-Ar interaction several potentials have been proposed. These potentials have been derived starting from different bulk property data as well as spectroscopic and differential cross section data. The measurements of the glory structure in the total cross section as performed by Bredewout (1976) provided in principle an essential test for the existing potentials. However, the overall energy dependence of the measured cross sections was not in agreement with the theoretically predicted C 6 and C 8 values. Therefore new measurements were performed with improved angular and velocity resolution. There are still differences between the results of the measured and calculated cross sections. However, the energy dependence of the cross section remains within the limits to be expected from the theoretical predictions. (Auth.)

  19. Quanto custa pagar tributos?

    OpenAIRE

    Bertolucci, Aldo V; Nascimento, Diogo Toledo do

    2002-01-01

    O custo de pagar tributos não se restringe ao tributo em si, mas refere-se a todos os aspectos formais e burocráticos de que os contribuintes têm de cuidar por determinação legal. O estudo desses custos se iniciou recentemente no mundo e só em 2001 começou a ser pesquisado no Brasil. Este trabalho apresenta um panorama dos estudos mundiais a respeito do tema e o resultado de pesquisa realizada junto às companhias de capital aberto no Brasil. A pesquisa confirma as tendências mundiais e estima...

  20. Liquidez corrente e rentabilidade: relação com o indicador de estrutura financeira do Modelo Fleuriet através de levantamento em mais de 2.200 demonstrações financeiras de sociedades anônimas de 23 setores da economia brasileira em 2009, 2010 e 2011

    OpenAIRE

    Montoto, Eugenio Roballo

    2013-01-01

    O objetivo desta dissertação é determinar as relações entre os índices liquidez corrente e de rentabilidade (lucro sobre patrimônio líquido) com o indicador de estrutura financeira associado ao modelo FLEURIET. Há poucos trabalhos nas bases de dados pesquisadas sobre o modelo Fleuriet até o momento. A maioria dos trabalhos até esta data foram feitos com amostras pequenas de sociedades anônimas de capital aberto e chegaram à conclusão de que estamos diante de um modelo consistente de gestão do...

  1. Efeitos de um programa de reabilitação acelerado após o tratamento cirúrgico da ruptura aguda do tendão de Aquiles

    OpenAIRE

    Ott, Rafael Duvelius

    2010-01-01

    Objetivo: Avaliar os efeitos de um protocolo acelerado de reabilitação (ACE) versus um protocolo tradicional de imobilização do tornozelo (TRA) sobre a função muscular e articular, após o tratamento cirúrgico da ruptura aguda do tendão de Aquiles. Método: 37 pacientes com diagnóstico de ruptura aguda do tendão de Aquiles foram submetidos ao tratamento cirúrgico aberto com reparo término-terminal pela técnica de Krackow. Após a cirurgia, foram divididos em dois grupos: no grupo ACE foi utiliza...

  2. Development of a Control and Vision Interface for an AR.Drone

    Directory of Open Access Journals (Sweden)

    Cheema Prasad

    2016-01-01

    Full Text Available The AR.Drone is a remote controlled quadcopter which is low cost, and readily available for consumers. Therefore it represents a simple test-bed on which control and vision research may be conducted. However, interfacing with the AR.Drone can be a challenge for new researchers as the AR.Drone's application programming interface (API is built on low-level, bit-wise, C instructions. Therefore, this paper will demonstrate the use of an additional layer of abstraction on the AR.Drone’s API via the Robot Operating System (ROS. Using ROS, the construction of a high-level graphical user interface (GUI will be demonstrated, with the explicit aim of assisting new researchers in developing simple control and vision algorithms to interface with the AR.Drone. The GUI, formally known as the Control and Vision Interface (CVI is currently used to research and develop computer vision, simultaneous localisation and mapping (SLAM, and path planning algorithms by a number of postgraduate and undergraduate students at the school of Aeronautical, Mechanical, and Mechatronics Engineering (AMME in The University of Sydney.

  3. Cerebral artery alpha-1 AR subtypes: high altitude long-term acclimatization responses.

    Directory of Open Access Journals (Sweden)

    Ravi Goyal

    Full Text Available In response to hypoxia and other stress, the sympathetic (adrenergic nervous system regulates arterial contractility and blood flow, partly through differential activities of the alpha1 (α1 - adrenergic receptor (AR subtypes (α1A-, α1B-, and α1D-AR. Thus, we tested the hypothesis that with acclimatization to long-term hypoxia (LTH, contractility of middle cerebral arteries (MCA is regulated by changes in expression and activation of the specific α1-AR subtypes. We conducted experiments in MCA from adult normoxic sheep maintained near sea level (300 m and those exposed to LTH (110 days at 3801 m. Following acclimatization to LTH, ovine MCA showed a 20% reduction (n = 5; P<0.05 in the maximum tension achieved by 10-5 M phenylephrine (PHE. LTH-acclimatized cerebral arteries also demonstrated a statistically significant (P<0.05 inhibition of PHE-induced contractility in the presence of specific α1-AR subtype antagonists. Importantly, compared to normoxic vessels, there was significantly greater (P<0.05 α1B-AR subtype mRNA and protein levels in LTH acclimatized MCA. Also, our results demonstrate that extracellular regulated kinase 1 and 2 (ERK1/2-mediated negative feedback regulation of PHE-induced contractility is modulated by α1B-AR subtype. Overall, in ovine MCA, LTH produces profound effects on α1-AR subtype expression and function.

  4. Sedimentary cycles and volcanic ash beds in the Lower Pliocene lacustrine succession of Ptolemais (NW Greece): discrepancy between 40 Ar/39 Ar and astronomical ages

    NARCIS (Netherlands)

    Steenbrink, J.; Vugt, N. van; Hilgen, F.J.; Wijbrans, J.R.; Meulenkamp, J.E.

    1999-01-01

    A high-resolution cyclostratigraphy for the rhythmically bedded lignite-marl sequences of the Lower Pliocene Ptole-mais Formation is combined with 40 Ar= 39 Ar dating results of intercalated volcanic ash beds. Detailed field reconnaissance in three open-pit lignite mines reveals three end-member

  5. Splicing Factor Prp8 Interacts With NES(AR) and Regulates Androgen Receptor in Prostate Cancer Cells.

    Science.gov (United States)

    Wang, Dan; Nguyen, Minh M; Masoodi, Khalid Z; Singh, Prabhpreet; Jing, Yifeng; O'Malley, Katherine; Dar, Javid A; Dhir, Rajiv; Wang, Zhou

    2015-12-01

    Androgen receptor (AR) plays a pivotal role in the development of primary as well as advanced castration-resistant prostate cancer. Previous work in our lab identified a novel nuclear export signal (NES) (NES(AR)) in AR ligand-binding domain essential for AR nucleocytoplasmic trafficking. By characterizing the localization of green fluorescence protein (GFP)-tagged NES(AR), we designed and executed a yeast mutagenesis screen and isolated 7 yeast mutants that failed to display the NES(AR) export function. One of those mutants was identified as the splicing factor pre-mRNA processing factor 8 (Prp8). We further showed that Prp8 could regulate NES(AR) function using short hairpin RNA knockdown of Prp8 coupled with a rapamycin export assay in mammalian cells and knockdown of Prp8 could induce nuclear accumulation of GFP-tagged AR in PC3 cells. Prp8 expression was decreased in castration-resistant LuCaP35 xenograft tumors as compared with androgen-sensitive xenografts. Laser capture microdissection and quantitative PCR showed Prp8 mRNA levels were decreased in human prostate cancer specimens with high Gleason scores. In prostate cancer cells, coimmunoprecipitation and deletion mutagenesis revealed a physical interaction between Prp8 and AR mainly mediated by NES(AR). Luciferase assay with prostate specific antigen promoter-driven reporter demonstrated that Prp8 regulated AR transcription activity in prostate cancer cells. Interestingly, Prp8 knockdown also increased polyubiquitination of endogenous AR. This may be 1 possible mechanism by which it modulates AR activity. These results show that Prp8 is a novel AR cofactor that interacts with NES(AR) and regulates AR function in prostate cancer cells.

  6. Caixa é dívida negativa sob a perspectiva de hedging no Brasil?

    Directory of Open Access Journals (Sweden)

    Marcio Telles Portal

    2013-01-01

    Full Text Available O presente estudo investigou se as companhias brasileiras de capital aberto, entre 1995 e 2008, coordenam as políticas de caixa e dívida para efeitos de hedging contra subinvestimento em condições de restrição financeira. Os resultados indicam a inexistência de um componente de hedging usando, simultaneamente, as políticas de caixa e dívida em companhias restritas. Foi observada para as companhias restritas financeiramente uma sensibilidade positiva do caixa ao fluxo de caixa e sensibilidade negativa da dívida ao fluxo de caixa, independentemente da necessidade de hedging. As companhias irrestritas não apresentaram uma sensibilidade do caixa ao fluxo de caixa significante estatisticamente, mas apresentaram sensibilidade negativa da dívida ao fluxo de caixa, resultados também independentes da necessidade de hedging. As evidências contrariam os resultados encontrados por Acharya, Almeida e Campello (2007 no mercado norte-americano, onde caixa e dívida negativa apresentaram de acordo com a necessidade de hedging diferentes papéis na otimização intertemporal dos investimentos em companhias restritas.

  7. Absolute total and one and two electron transfer cross sections for Ar8+ on Ar as a function of energy

    International Nuclear Information System (INIS)

    Vancura, J.; Kostroun, V.O.

    1992-01-01

    The absolute total and one and two electron transfer cross sections for Ar 8+ on Ar were measured as a function of projectile laboratory energy from 0.090 to 0.550 keV/amu. The effective one electron transfer cross section dominates above 0.32 keV/amu, while below this energy, the effective two electron transfer starts to become appreciable. The total cross section varies by a factor over the energy range explored. The overall error in the cross section measurement is estimated to be ± 15%

  8. PROBLEMAS RELACIONADOS AO USO DE ESTEROIDES ANABÓLICOS ANDROGÊNICOS (EAA POR PRATICANTES DE MUSCULAÇÃO E O PAPEL DO FARMACÊUTICO NA EDUCAÇÃO DESTES ATLETAS DE MODO A REDUZIR O USO INDISCRIMINADO

    Directory of Open Access Journals (Sweden)

    Aline Oliveira de SOUZA, Andrews Marques do NASCIMENTO, Eduardo Roberto COLE

    2013-12-01

    Full Text Available A busca pelo corpo perfeito está assumindo proporções assustadoras em todas as partes do mundo. O culto ao corpo desencadeou uma busca desenfreada por artifícios que permitam alcançar um ideal de beleza fora da realidade para a maior parte da população. Dentre estes artifícios, destaca-se o uso de esteroides anabólicos androgênicos (EAA. Os EAA sintéticos são substâncias consideradas “construtoras” de músculos, pois conseguem potencializar os efeitos do exercício físico sobre os músculos, que apresentam efeitos semelhantes aos da testosterona, promovendo aumento da força de contratilidade e do volume das células musculares. O farmacêutico, enquanto profissional devidamente habilitado em medicamentos, insere-se neste contexto de forma decisiva, assumindo o papel de “educador em saúde”, e esclarecendo aos usuários (ou futuros usuários sobre os riscos inerentes a tal prática. A participação efetiva do profissional farmacêutico em um trabalho educativo direcionado aos usuários dessas drogas é de suma importância, atuando de forma decisiva no desencorajamento do uso de EAA ao se depararem nas drogarias com indivíduos intencionados a fazer o uso não médico/ilícito de EAA, procurando sempre abordagens que fujam das tradicionais campanhas de conscientização (que poucos resultados têm obtido nos últimos anos.

  9. Editorial dossier “plea bargain and bargaining criminal justice: new and multiples points of view”

    Directory of Open Access Journals (Sweden)

    Soraia da Rosa Mendes

    2017-03-01

    Full Text Available Tal como poucos o tema da barganha e da justiça criminal negocial tem sido um dos principais pontos de acaloradas discussões dentro da pauta de assuntos do processo penal no mundo e, de algum tempo, também no Brasil. Neste sentido, o dossiê  "Colaboração Premiada e Justiça Criminal Negocial" tem como objetivo propiciar um espaço amplo e aberto às analises e estudos daqueles que se debruçam sobre os principais aspectos do instituto da colaboração/delação premiada em suas diversas interfaces, como, por exemplo: ao sistema de justiça criminal negocial no direito comparado; à ação penal pública e oportunidade; à celebração do acordo e a decretação de medidas cautelares; ao controle dos acordos durante a investigação preliminar; aos limites constitucionais de atuação do Ministério Público investigador, acusador e negociador; ao sistema acusatório e o papel do Poder Judiciário nos acordos; e aos direitos do colaborador e a atuação da mídia.

  10. Benchmark calculations with correlated molecular wave functions. IX. The weakly bound complexes Ar - H2 and Ar - HCl

    International Nuclear Information System (INIS)

    Woon, D.E.; Peterson, K.A.; Dunning, T.H. Jr.

    1998-01-01

    The interaction of Ar with H 2 and HCl has been studied using Moeller - Plesset perturbation theory (MP2, MP3, MP4) and coupled-cluster [CCSD, CCSD(T)] methods with augmented correlation consistent basis sets. Basis sets as large as triply augmented quadruple zeta quality were used to investigate the convergence trends. Interaction energies were determined using the supermolecule approach with the counterpoise correction to account for basis set superposition error. Comparison with the available empirical potentials finds excellent agreement for both binding energies and transition state. For Ar - H 2 , the estimated complete basis set (CBS) limits for the binding energies of the two equivalent minima and the connecting transition state (TS) are, respectively, 55 and 47cm -1 at the MP4 level and 54 and 46cm -1 at the CCSD(T) level, respectively [the XC(fit) empirical potential of Bissonnette et al. [J. Chem. Phys. 105, 2639 (1996)] yields 56.6 and 47.8cm -1 for H 2 (v=0)]. The estimated CBS limits for the binding energies of the two minima and transition state of Ar - HCl are 185, 155, and 109cm -1 at the MP4 level and 176, 147, and 105cm -1 at the CCSD(T) level, respectively [the H6(4,3,0) empirical potential of Hutson [J. Phys. Chem. 96, 4237 (1992)] yields 176.0, 148.3, and 103.3cm -1 for HCl (v=0)]. Basis sets containing diffuse functions of (dfg) symmetries were found to be essential for accurately modeling these two complexes, which are largely bound by dispersion and induction forces. Highly correlated wave functions were also required for accurate results. This was found to be particularly true for ArHCl, where significant differences in calculated binding energies were observed between MP2, MP4, and CCSD(T). copyright 1998 American Institute of Physics

  11. AR DOC: Augmented reality documentaries

    DEFF Research Database (Denmark)

    Vistisen, Peter

    2014-01-01

    Augmented Reality Documentaries (AR DOC) er et ’lille’ Shareplay projekt (ansøgte midler augmented reality cross media løsninger, til at skabe engagerende publikumsformidling...... indenfor oplevelsesindustrien. Projektet har genereret ny viden omkring, hvordan fysisk og digital formidling kan understøttes via Augmented Reality som formidlingsformat....

  12. Emergency preparedness with Ar-41 measurement

    International Nuclear Information System (INIS)

    Kunst, Juan J.; Rodriguez, Monica; Ugarte, Ricardo; Vigile, Sebastian; Boutet, Luis; Jordan, Osvaldo; Hernandez, Daniel

    2008-01-01

    Full text: The Nuclear Regulatory Authority (ARN) of Argentina is training their intervention group in the forecast of radiological consequences in case of a radiological or nuclear accident. In this context it has begun the measurement of Ar-41 near the research reactor RA3. It is well known the Ar-41 production inside research reactor, and it has been studied like a good mean to validate atmosphere dispersion model occurrence, or to develop method to improve the estimation of the characteristic of the emission. The measurements were made in two laboratories of ARN, Gamma measurement Laboratory, and CTC (Total Body Counter) Laboratory near the research reactor RA3. The emission of Ar-41 were determined by Measurements Group of Environmental Control Division inside the research reactor. The laboratories are at SE and ESE direction from the reactor. After the passage of a cold front, the wind flown from SE, in this situation and if the reactor is operating we could detect the presence of Ar-41 in the environment. This meteorological situation can be forecast by information submitted by National Meteorological Service of Argentina (SMN) in a meteograma. To correlate and evaluate the concentration in this laboratory, first it was determined the direction and persistence of wind in the site using the forecast of the National Meteorological Service (SMN) of Argentina to establish when the detectors were irradiated, during the radiological measurements, the real time wind direction an velocities measurement were did, with a site meteorological tower. With this information and cloudiness we determined de stability class and concentration. To determine concentration we used the code Hotspot and our code SEDA developed in ARN. In this paper are present the calibration of GeH detectors, and the location of them. We present several measurements did in this experience. We analyze the capacity developed by our teams to predict changes in wind direction and concentrations

  13. In situ dating on Mars: A new approach to the K-Ar method utilizing cosmogenic argon

    Science.gov (United States)

    Cassata, William S.

    2014-01-01

    Cosmogenic argon isotopes are produced in feldspars via nuclear reactions between cosmic rays and Ca and K atoms within the lattice. These cosmogenic isotopes can be used as proxies for K and Ca, much like nuclear reactor-derived 39Ar and 37Ar are used as proxies for K and Ca, respectively, in 40Ar/39Ar geochronology. If Ca and K are uniformly distributed, then the ratio of radiogenic 40Ar (40Ar*) to cosmogenic 38Ar or 36Ar (38Arcos or 36Arcos) is proportional to the difference between the radioisotopic and exposure ages, as well as the K/Ca ratio of the degassing phase. Thus cosmogenic, radiogenic, and trapped Ar isotopes, all of which can be measured remotely and are stable over geologic time, are sufficient to generate an isochron-like diagram from which the isotopic composition of the trapped component may be inferred. Such data also provide a means to assess the extent to which the system has remained closed with respect to 40Ar*, thereby mitigating otherwise unquantifiable uncertainties that complicate the conventional K-Ar dating method.

  14. Bacillus sp.CDB3 isolated from cattle dip-sites possesses two ars gene clusters

    Institute of Scientific and Technical Information of China (English)

    Somanath Bhat; Xi Luo; Zhiqiang Xu; Lixia Liu; Ren Zhang

    2011-01-01

    Contamination of soil and water by arsenic is a global problem.In Australia, the dipping of cattle in arsenic-containing solution to control cattle ticks in last centenary has left many sites heavily contaminated with arsenic and other toxicants.We had previously isolated five soil bacterial strains (CDB1-5) highly resistant to arsenic.To understand the resistance mechanism, molecular studies have been carried out.Two chromosome-encoded arsenic resistance (ars) gene clusters have been cloned from CDB3 (Bacillus sp.).They both function in Escherichia coli and cluster 1 exerts a much higher resistance to the toxic metalloid.Cluster 2 is smaller possessing four open reading frames (ORFs) arsRorf2BC, similar to that identified in Bacillus subtilis Skin element.Among the eight ORFs in cluster 1 five are analogs of common ars genes found in other bacteria, however, organized in a unique order arsRBCDA instead of arsRDABC.Three other putative genes are located directly downstream and designated as arsTIP based on the homologies of their theoretical translation sequences respectively to thioredoxin reductases, iron-sulphur cluster proteins and protein phosphatases.The latter two are novel of any known ars operons.The arsD gene from Bacillus species was cloned for the first time and the predict protein differs from the well studied E.coli ArsD by lacking two pairs of C-terrninal cysteine residues.Its functional involvement in arsenic resistance has been confirmed by a deletion experiment.There exists also an inverted repeat in the intergenic region between arsC and arsD implying some unknown transcription regulation.

  15. Ar ion beam mixing at gold-silicon interfaces

    International Nuclear Information System (INIS)

    Li Yupu; Chen Jian; Liu Jiarui; Zhang Qichu

    1987-01-01

    Ar-ion beam mixing at Au-Si interface is investigated systematically as a function of the energy of Ar-ion beam (100-300 keV), dose (5 x 10 15 - 8 x 10 16 /cm 2 ), dose rate (1.6 - 16 μA/cm 2 ) and substrate temperature (77 - 573 K). Very good ion beam mixing is obtained when the Ar-ion range distribution R p ± ΔR p fits the gold film thickness, where R p is the projected range and ΔR p is the standard deviation. At LN 2 temperature, the mixing amount is proportional to the square root of the dose but independent of the dose rate and the mixing process can be explained by the random walking model for the cascade process. At room temperature the dose rate effect is observed because of the beam current induced temperature effect. The temperature effect of the mixing amount, the uniformity, the thickness of mixing layers and the phase structure are observed

  16. Excitation function measurements of sup 4 sup 0 Ar(p,3n) sup 3 sup 8 K, sup 4 sup 0 Ar(p,2pn) sup 3 sup 8 Cl and sup 4 sup 0 Ar(p,2p) sup 3 sup 9 Cl reactions

    CERN Document Server

    Nagatsu, K; Suzuki, K

    1999-01-01

    For the production of sup 3 sup 8 K, excitation functions of the sup 4 sup 0 Ar(p,3n) sup 3 sup 8 K reaction and its accompanying reactions sup 4 sup 0 Ar(p,2pn) sup 3 sup 8 Cl, and sup 4 sup 0 Ar(p,2p) sup 3 sup 9 Cl were measured at the proton energy of 20.5-39.5 MeV to determine the optimum conditions of irradiation. Target cells containing argon gas were prepared using specially developed tools in an argon-replaced glove box. In the sup 4 sup 0 Ar(p,3n) sup 3 sup 8 K, sup 4 sup 0 Ar(p,2pn) sup 3 sup 8 Cl, and sup 4 sup 0 Ar(p,2p) sup 3 sup 9 Cl reactions, the maximum cross sections were 6.7+-0.7, 34+-3.3 and 11+-1.2mbarn at 37.6, 39.5 and 32.0 MeV, respectively, and the saturation thick target yields were calculated to be 560, 2200, and 1300 sup * MBq/mu A, respectively, at an incident energy of 39.5 MeV ( sup * integral yield above 21 MeV).

  17. A publicação de dados governamentais abertos: proposta de revisão da classe sobre Previdência Social do Vocabulário Controlado do Governo Eletrônico

    Directory of Open Access Journals (Sweden)

    Cláudio José Silva Ribeiro

    Full Text Available Este trabalho analisa a classe sobre Previdência Social do Vocabulário Controlado do Governo Eletrônico, investigando a publicação de dados governamentais abertos, realizada pela Empresa de Tecnologia e Informações da Previdência Social. Trata-se de um estudo exploratório, com objetivo de propor a revisão da classe sobre Previdência Social no domínio do Governo Eletrônico brasileiro, a fim de ampliar e corrigir a representação da área. O trabalho utiliza como metodologia: (1 pesquisa bibliográfica, para fundamentação teórica; (2 seleção da classe de assunto sobre Previdência Social do Vocabulário Controlado do Governo Eletrônico, como recorte; (3 análise dos pontos relacionados à categorização, linguagem escolhida (natural ou artificial, cobertura dos termos pertencentes ao escopo da classe de assunto estudado e relações apresentadas entre os termos; (4 propostas para revisão da classe estudada. O estudo aponta, nos resultados, falhas estruturais e inconsistências conceituais localizados no vocabulário. Discute a necessidade de se utilizarem vocabulários consistentes para representação dos dados publicados, a fim de torná-los legíveis por máquina e compartilháveis entre aplicações de software. Afirma que se deve investir em vocabulários já existentes para evitar esforços com a criação de outros instrumentos de representação. Julga necessário que outros órgãos públicos, além da Empresa de Tecnologia e Informações da Previdência Social, interessem-se em analisar e propor alterações e atualizações nas classes cuja temática contemple os dados por eles geridos. Conclui que a utilização do Vocabulário Controlado do Governo Eletrônico pode ir além de um mapa para navegação em páginas eletrônicas do setor público brasileiro, constituindo instrumento dinâmico de organização do conhecimento, podendo ser utilizado para diversos fins, de acordo com os interesses de cada usuário.

  18. AR coating with high damage threshold on SiO2 glass. Final report

    International Nuclear Information System (INIS)

    Toratani, H.; Kanamori, C.; Nakajima, S.; Nakagawa, K.; Izumitani, T.

    1983-01-01

    The following experimental results are shown: (1) uniformity of AR coatings on Optosil and Sprasil provided by LLNL; (2) relation between cleaning methods and properties of AR coatings; (3) baking and sintering conditions of gel-derived films; (4) heat treatment of AR coating in O 2 flow

  19. Efeito de níveis de água, coberturas do solo e condições ambientais na temperatura do solo e no cultivo de morangueiro em ambiente protegido e a céu aberto Effect of water levels, soil covers and enviroment in maximum soil temperature in strawberry crop in field and greenhouse

    Directory of Open Access Journals (Sweden)

    Regina C. de M. Pires

    2004-12-01

    Full Text Available A temperatura do solo é um importante parâmetro no cultivo do morangueiro, pois interfere no desenvolvimento vegetativo, na sanidade e na produção. O objetivo do presente trabalho foi avaliar o efeito de diferentes níveis de água, coberturas de canteiro em campo aberto e em ambiente protegido, na temperatura máxima do solo no cultivo do morangueiro. Foram realizados dois experimentos: um em cultivo protegido e outro a campo aberto, em Atibaia - SP, em esquema fatorial 2 x 3 (coberturas do solo e níveis de irrigação, em blocos ao acaso, com cinco repetições. As coberturas de solo utilizadas foram filmes de polietileno preto e transparente. A irrigação localizada foi aplicada por gotejo sempre que o potencial de água no solo atingisse -0,010 (N1, -0,035 (N2 e -0,070 (N3 MPa, em tensiômetros instalados a 10 cm de profundidade. A temperatura do solo foi avaliada por termógrafos, sendo os sensores instalados a 5 cm de profundidade. Houve influência do ambiente de cultivo, da cobertura do solo e dos níveis de irrigação na temperatura máxima do solo. A temperatura do solo sob diferentes coberturas dependeu não somente das características físicas do plástico, como também da forma de instalação no canteiro. A temperatura máxima do solo aumentou com a diminuição do potencial da água no solo, no momento da irrigação.The soil temperature is an important parameter in strawberry crop, because, it interferes in vegetative development, plant health conditions and yield. The aim of this work was to evaluate the effect of different water levels, soil covers in field conditions and greenhouse in maximum soil temperature in strawberry crop. Two experiments were accomplished, one in greenhouse and other in field conditions, at Atibaia - SP, Brazil. The experimental design was a factorial 2 x 3 (soil covers and water levels, with 5 repetitions. The soil covers were clear and black plastics. The trickle irrigation was applied

  20. Regulation of AR Degradation and Function by Ubiquitylation

    Science.gov (United States)

    2015-10-01

    have carried out similar analyses from androgen ( DHT ) stimulated VCaP cells. The combined results from a series of LC-MS/MS analyses of DHT stimulated...minus or plus DHT . AR was then isolated from whole cell lysates and run on SDS-PAGE, followed by excision of area ~100 Kd (mono or possibly oligo...the stably expressed AR WT versus K911R mutant. As shown in figure 1B, the K911R mutant had increased activity in response to 1 nM DHT . Finally

  1. Dissociative recombination of rare gas hydride ions: II. ArH+

    International Nuclear Information System (INIS)

    Mitchell, J B A; Novotny, O; LeGarrec, J L; Florescu-Mitchell, A; Rebrion-Rowe, C; Stolyarov, A V; Child, M S; Svendsen, A; Ghazaly, M A El; Andersen, L H

    2005-01-01

    A storage ring measurement of the rate coefficient for the production of neutral Ar in e + ArH + collisions is described. It is found that the recombination rate is too small to measure at low centre-of-mass energies but the combined rate coefficient for dissociative recombination and dissociative excitation increases above 2.5 eV displaying peaks centred at 7.5 eV, 16 and 26 eV. Calculated potential energy curves for the ground and excited states of ArH + are presented and these aid in the elucidation of the recombination and excitation processes observed at higher energies. The implications for plasma modelling are discussed. (letter to the editor)

  2. Recurrent Early Cretaceous, Indo-Madagascar (89-86 Ma) and Deccan (66 Ma) alkaline magmatism in the Sarnu-Dandali complex, Rajasthan: 40Ar/39Ar age evidence and geodynamic significance

    Science.gov (United States)

    Sheth, Hetu; Pande, Kanchan; Vijayan, Anjali; Sharma, Kamal Kant; Cucciniello, Ciro

    2017-07-01

    The Sarnu-Dandali alkaline complex in Rajasthan, northwestern India, is considered to represent early, pre-flood basalt magmatism in the Deccan Traps province, based on a single 40Ar/39Ar age of 68.57 Ma. Rhyolites found in the complex are considered to be 750 Ma Malani basement. Our new 40Ar/39Ar ages of 88.9-86.8 Ma (for syenites, nephelinite, phonolite and rhyolite) and 66.3 ± 0.4 Ma (2σ, melanephelinite) provide clear evidence that whereas the complex has Deccan-age (66 Ma) components, it is dominantly an older (by 20 million years) alkaline complex, with rhyolites included. Basalt is also known to underlie the Early Cretaceous Sarnu Sandstone. Sarnu-Dandali is thus a periodically rejuvenated alkaline igneous centre, active twice in the Late Cretaceous and also earlier. Many such centres with recurrent continental alkaline magmatism (sometimes over hundreds of millions of years) are known worldwide. The 88.9-86.8 Ma 40Ar/39Ar ages for Sarnu-Dandali rocks fully overlap with those for the Indo-Madagascar flood basalt province formed during continental breakup between India (plus Seychelles) and Madagascar. Recent 40Ar/39Ar work on the Mundwara alkaline complex in Rajasthan, 120 km southeast of Sarnu-Dandali, has also shown polychronous emplacement (over ≥ 45 million years), and 84-80 Ma ages obtained from Mundwara also arguably represent post-breakup stages of the Indo-Madagascar flood basalt volcanism. Remnants of the Indo-Madagascar province are known from several localities in southern India but hitherto unknown from northwestern India 2000 km away. Additional equivalents buried under the vast Deccan Traps are highly likely.

  3. A Framework for Designing Collaborative Learning Environments Using Mobile AR

    Science.gov (United States)

    Cochrane, Thomas; Narayan, Vickel; Antonczak, Laurent

    2016-01-01

    Smartphones provide a powerful platform for augmented reality (AR). Using a smartphone's camera together with the built in GPS, compass, gyroscope, and touch screen enables the real world environment to be overlaid with contextual digital information. The creation of mobile AR environments is relatively simple, with the development of mobile AR…

  4. Suporte relacionado ao cuidado em saúde ao doente com aids: o modelo de comboio e a enfermagem

    Directory of Open Access Journals (Sweden)

    Edilene Aparecida Araújo da Silveira

    2011-06-01

    Full Text Available O presente estudo teve como objetivo conhecer a relação e a troca de suporte entre o doente com AIDS e pessoas à sua volta. O estudo está baseado no modelo de comboio das relações sociais que tem como uma de suas características a representação da rede em três círculos concêntricos. Os participantes eram pessoas que estavam internadas e que falaram sobre o suporte relacionado ao cuidado em saúde proporcionado por pessoas próximas, ou seja, que pertenciam ao círculo interno do comboio. A maioria dos participantes descreveu o círculo como sendo composto por no máximo cinco integrantes, sendo que pessoas da família foram as mais citadas. Os profissionais de saúde precisam conhecer o paciente e seu comboio, reconhecendo-os no contexto psicossocial e cultural de forma a favorecer a aceitação da soropositividade, mudanças no estilo de vida, ajuda nos cuidados de saúde e adesão ao tratamento.

  5. Through the Loupe: Visitor engagement with a primarily text-based handheld AR application

    NARCIS (Netherlands)

    van der Vaart, M.; Damala, A.; Guidi, G; Scopigno, R.; Torres, J.C.; Graf, H.; Remondino, F.; Duranti, L.; Brunet, P.; Hazan, S.; Barceló, J.

    2015-01-01

    The use of Augmented Reality (AR) in a museum or heritage setting holds great potential. However, until now, introducing AR into their buildings has been prohibitively expensive for most museums. On the one hand, programming the AR application could not be done in-house and would be rather costly.

  6. Timing of Hydrocarbon Fluid Emplacement in Sandstone Reservoirs in Neogene in Huizhou Sag, Southern China Sea, by Authigenic Illite 40Ar- 39Ar Laser Stepwise Heating

    Science.gov (United States)

    Hesheng, Shi; Junzhang, Zhu; Huaning, Qiu; yu, Shu; Jianyao, Wu; Zulie, Long

    Timing of oil or gas emplacements is a new subject in isotopic geochronology and petroleum geology. Hamilton et al. expounded the principle of the illite K-Ar age: Illite is often the last or one of the latest mineral cements to form prior to hydrocarbon accumulation. Since the displacement of formation water by hydrocarbons will cause silicate diagenesis to cease, K-Ar ages for illite will constrain the timing of this event, and also constrain the maximum age of formation of the trap structure. In this study, the possibility of authigenic illites 40Ar- 39Ar dating has been investigated. The illite samples were separated from the Tertiary sandstones in three rich oil reservoir belts within the Huizhou sag by cleaning, fracturing by cycled cooling-heating, soxhlet-extraction with solvents of benzene and methanol and separating with centrifugal machine. If oil is present in the separated samples, ionized organic fragments with m/e ratios of 36 to 40 covering the argon isotopes will be yielded by the ion source of a mass spectrometer, resulting in wrong argon isotopic analyses and wrong 40Ar- 39Ar ages. The preliminary experiments of illite by heating did show the presence of ionized organic fragments with m/e ratios of 36 to 44. In order to clean up the organic gases completely and obtain reliable analysis results, a special purification apparatus has been established by Qiu et al. and proved valid by the sequent illite analyses. All the illite samples by 40Ar- 39Ar IR-laser stepwise heating yield stair-up age spectra in lower laser steps and plateaux in higher laser steps. The youngest apparent ages corresponding to the beginning steps are reasonable to be interpreted for the hydrocarbon accumulation ages. The weighted mean ages of the illites from the Zhuhai and Zhujiang Formations are (12.1 ± 1.1) Ma and (9.9 ± 1.2) Ma, respectively. Therefore, the critical emplacement of petroleum accumulation in Zhujiang Formation in Huizhou sag took place in ca 10 Ma. Late

  7. Dating of ice and ocean samples with Atom Trap Trace Analysis of 39Ar

    OpenAIRE

    Ebser, Sven Conrad

    2018-01-01

    The noble gas radioisotope 39Ar with a half-life of 269 years is an almost ideal tracer for dating ice and water samples in the time range of 50 to 1000 years ago, for which no other reliable methods exist. Due to its very low relative abundance of 39Ar/Ar = 8.1(3)*10^-16, 39Ar has only been routinely measured by Low-Level Counting so far. However, since Low-Level Counting requires samples in the order of 1000 L, the application of 39Ar, besides some proof-of-principle experiments, has been l...

  8. Backbendings of superdeformed bands in 36;40Ar

    Science.gov (United States)

    Xiang, Xu-Hui; He, Xiao-Tao

    2018-05-01

    Experimentally observed superdeformed (SD) rotational bands in 36Ar and 40Ar are studied by the cranked shell model (CSM) with the pairing correlations treated by a particle-number-conserving (PNC) method. This is the first time that PNC-CSM calculations have been performed on the light nuclear mass region around A=40. The experimental kinematic moments of inertia J (1) versus rotational frequency are reproduced well. The backbending of the SD band at frequency around ℏω=1.5 MeV in 36Ar is attributed to the sharp rise of the simultaneous alignments of the neutron and proton 1d 5/2[202]5/2 pairs and 1f 7/2[321]3/2 pairs, which is a consequence of the band crossing between the 1d 5/2[202]5/2 and 1f 7/2[321]3/2 configuration states. The gentle upbending at low frequency of the SD band in 40Ar is mainly affected by the alignments of the neutron 1f 7/2[321]3/2 pairs and proton 1d 5/2[202]5/2 pairs. The PNC-CSM calculations show that besides the diagonal parts, the off-diagonal parts of the alignments play an important role in the rotational behavior of the SD bands. Supported by National Natural Science Foundation of China (11775112 and 11275098) and the Priority Academic Program Development of Jiangsu Higher Education Institutions

  9. The immunohistochemical expression and potential prognostic value of HDAC6 and AR in invasive breast cancer.

    Science.gov (United States)

    Li, Congying; Cao, Lu; Xu, Cong; Liu, Fang; Xiang, Guomin; Liu, Xiaozhen; Jiao, Jiao; Niu, Yun

    2018-05-01

    Previous studies have investigated the role of histone deacetylase 6 (HDAC6) in the regulation of androgen receptor (AR) in prostate cancer; however, the role of HDAC6 has not yet been clearly identified in breast cancer. The aim of this study was to examine the expression of HDAC6 and AR, determine the correlation between HDAC6 and AR, and assess the prognostic value of HDAC6 and AR in breast cancer. A total of 228 cases of invasive breast cancer were randomly selected. The expression of HDAC6 and AR was analyzed by immunohistochemistry. χ 2 Tests were performed to determine the association between conventional clinicopathological factors and HDAC6, AR, and HDAC6/AR co-expression. Spearman correlation methods were performed to determine the correlation between HDAC6 and AR, and Kaplan-Meier analyses were performed to determine the prognostic impact of HDAC6, AR and HDAC6/AR co-expression; 58.8% (134/228) patients exhibited high expression of HDAC6. High HDAC6 expression was significantly associated with high histologic grade (G3) (PAR expression levels were significantly associated (r=0.382, PAR+ groups (PAR and HDAC6 and HDAC6/AR co-expression had a worse clinical prognosis. The expression levels of HDAC6 and AR are correlated in breast cancer; moreover, HDAC6 and AR have prognostic value in predicting the overall survival (OS) of ER-negative breast cancer patients. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. A cryptic Early Palaeozoic event in the Narcea Antiform? 40Ar/39Ar amphibole data in the Puente de Selce granitoid

    OpenAIRE

    Gutiérrez Alonso, Gabriel; Fernández Suárez, J.; Keppie, J. D.; Ortega Rivera, M. A.; Lee, J. K. W.; Murphy, J. B.

    2005-01-01

    Las edades 40Ar/39Ar obtenidas a partir de anfíboles del granitoide Neoproterozoico de Puente de Selce, localizado en el Antiforme del Narcea junto con la existencia de fábricas de deformación relictas generadas en condiciones de media-alta temperatura en las mismas rocas puede ser interpretada como debida a un evento críptico de edad Paleozoico Inferior fuertemente retrabajado durante la deformación varisca. La naturaleza y la cinemática de este posible evento no pueden precisars...

  11. "ARS 01", perspektiivide avamine / Helen Kivisoo

    Index Scriptorium Estoniae

    Kivisoo, Helen

    2001-01-01

    30. IX 2001-20. I 2002 Kiasmas kuuendat korda toimuvast rahvusvahelisest näitusest "ARS", kus Eestist osaleb Marko Mäetamm. Kuraatorid Tuula Arkio, Maaretta Jaukkuri, Patrik Nyberg, Jari-Pekka Vanhala. Teemaks "kolmas ruum". Näituse kajastamisest.

  12. New Paleomagnetic and 40Ar/39Ar Geochronological Results for the South Shetland Islands, West Antarctica, and Their Tectonic Implications

    Science.gov (United States)

    Gao, Liang; Zhao, Yue; Yang, Zhenyu; Liu, Jianmin; Liu, Xiaochun; Zhang, Shuan-Hong; Pei, Junling

    2018-01-01

    To reconstruct the paleoposition of the Antarctic Peninsula relative to the South American Plate during the breakup of Gondwana, as well as the opening kinematics of the Drake Passage, we conducted detailed paleomagnetic, rock magnetic, and isotopic chronology studies of Byers Peninsula (Livingston Island) and Fildes Peninsula (King George Island) of the South Shetland Islands. The 40Ar/39Ar ages of the Agate Beach Formation to the Long Hill Formation in Fildes Peninsula range from 56.38 ± 0.2 Ma to 52.42 ± 0.19 Ma. Low natural remanent magnetization/isothermal remanent magnetization ratios, inconsistency with the polarity constrained by the paleomagnetic results and 40Ar/39Ar age constraints, as well as the widespread cation-deficient titanomagnetite and Ti-free magnetite of secondary origin, indicate that the volcanic and sedimentary rocks of Fildes Peninsula were remagnetized at about 55 Ma. Combining our results with previous data from the South Shetland Islands and the Antarctic Peninsula, we calculated the paleopoles for 110 Ma and 55 Ma for the South Shetland Islands and the Antarctic Peninsula. The paleomagnetic reconstruction of the relative paleoposition of the Antarctic Peninsula and South America shows that these plates were connected and experienced a southward movement and clockwise rotation from 110 to 55 Ma. Subsequently, southward translation and clockwise rotation of the Antarctic Peninsula between 55 and 27 Ma separated the Antarctic Peninsula and South America, forming the Drake Passage. Northward translation of South America after 27 Ma increased the N-S divergence and increased the distance between the Antarctic Peninsula and the South American Plate.

  13. Postcollision interactions in the Auger decay of the Ar L-shell

    Energy Technology Data Exchange (ETDEWEB)

    Samson, J.A.R.; Stolte, W.C.; He, Z.X. [Univ. of Nebraska, Lincoln, NE (United States)] [and others

    1997-04-01

    The photoionization cross sections for Ar{sup +} through Ar{sup 4+}, produced by the Auger decay of an inner shell 2p hole, have been measured between 242 eV and 253 eV on beamline 9.0.1 and 6.3.2. In this study the authors are interested in near threshold phenomenon involving postcollision interactions (PCI), which are related to the Auger decay of a vacancy in the Ar L-shell. During an Auger decay a postcollision interaction can occur causing the out-going photoelectron to be retarded thus losing a certain amount of energy. If the retardation is sufficiently large the photoelectron will not escape. This result produces a singly charged ion, which normally would not be present. Such evidence of electron capture by the PCI effect was first shown clearly by Eberhardt et al. and, with higher resolution, in the present work. However, capture of the photoelectron is expected to be 100% exactly at the L{sub 2,3} thresholds. Thus, from the authors results they would have expected the Ar{sup 2+} signal to be zero at threshold, but it was not? The authors can explain this anomoly on the basis that during the Auger decay the photoelectrons are captured into high lying excited states of Ar{sup +}, which subsequently decay through autoionization yielding Ar{sup 2+}. Future work in this area will seek experimental evidence to verify this prediction.

  14. Ar and K partitioning between clinopyroxene and silicate melt to 8 GPa

    Science.gov (United States)

    Chamorro, E. M.; Brooker, R. A.; Wartho, J.-A.; Wood, B. J.; Kelley, S. P.; Blundy, J. D.

    2002-02-01

    The relative incompatibility of Ar and K are fundamental parameters in understanding the degassing history of the mantle. Clinopyroxene is the main host for K in most of the upper mantle, playing an important role in controlling the K/Ar ratio of residual mantle and the subsequent time-integrated evolution of 40Ar/36Ar ratios. Clinopyroxene also contributes to the bulk Ar partition coefficient that controls the Ar degassing rate during mantle melting. The partitioning of Ar and K between clinopyroxene and quenched silicate melt has been experimentally determined from 1 to 8 GPa for the bulk compositions Ab80Di20 (80 mol% albite-20 mol% diopside) and Ab20Di80 with an ultraviolet laser ablation microprobe (UVLAMP) technique for Ar analysis and the ion microprobe for K. Data for Kr (UVLAMP) and Rb (ion probe) have also been determined to evaluate the role of crystal lattice sites in controlling partitioning. By excluding crystal analyses that show evidence of glass contamination, we find relatively constant Ar partition coefficients (DAr) of 2.6 × 10-4 to 3.9 × 10-4 for the Ab80Di20 system at pressures from 2 to 8 GPa. In the Ab20Di80 system, DAr shows similar low values of 7.0 × 10-5 and 3.0 × 10-4 at 1 to 3 GPa. All these values are several orders of magnitude lower than previous measurements on separated crystal-glass pairs. DK is 10 to 50 times greater than DRb for all experiments, and both elements follow parallel trends with increasing pressure, although these trends are significantly different in each system studied. The DK values for clinopyroxene are at least an order of magnitude greater than DAr under all conditions investigated here, but DAr appears to show more consistent behavior between the two systems than K or Rb. The partitioning behavior of K and Rb can be explained in terms of combined pressure, temperature, and crystal chemistry effects that result in changes for the size of the clinopyroxene M2 site. In the Ab20Di80 system, where

  15. Densidade crítica ao crescimento de plantas considerando água disponível e resistência à penetração de um Argissolo Vermelho distrófico arênico Bulk density critical to the growth of plants considering available water and soil resistance to penetration of a Paleudalf

    Directory of Open Access Journals (Sweden)

    Cláudia Liane Rodrigues de Lima

    2007-08-01

    Full Text Available O estabelecimento de culturas está associado a condições restritivas impostas pelo tipo e pelo manejo de solo. O objetivo deste estudo foi avaliar o intervalo de densidade crítica de um Argissolo Vermelho distrófico arênico, considerando a disponibilidade de água para as culturas e os valores restritivos de resistência à penetração (1,5; 2,0; 2,5; 3,0 e 3,5MPa. A amostragem de um Argissolo Vermelho distrófico arênico sob plantio direto desde 1989, com estrutura de solo preservada, foi feita nas camadas de 0,00 a 0,10 m e 0,10 a 0,20m. As amostras (oito repetições foram saturadas em água, equilibradas em diferentes potenciais (-0,001; -0,004; -0,006; -0,033; -0,07 e -0,1MPa e dois grupos de amostras foram secadas em laboratório, por um período de 7 e 9 dias, perfazendo um total de 128 amostras. Após atingir o equilíbrio, foi avaliada a resistência à penetração e a densidade do solo. Um incremento na resistência à penetração possibilitou maiores intervalos de densidade adequados ao desenvolvimento das plantas, i.e., quando considerada uma resistência à penetração de 2MPa, o intervalo de densidade adequado foi de 1,44Mg m-3 a 1,76Mg m-3 e, para uma resistência de 3MPa, o intervalo foi de 1,53 a 1,88Mg m-3. Valores superiores e inferiores ao intervalo de densidade obtidos são críticos ao desenvolvimento de culturas, considerando a resistência à penetração e a disponibilidade de água.Crop establishment is linked to restrictive conditions imposed by soil type and soil management. This study aimed at evaluating the interval of bulk density critical for a Paleudalf, considering water availability to the crops and restrictive values to the root resistance to penetration (1.5; 2.0; 2.5; 3.0 e 3.5MPa. Soil samples, from a Paleudalf under no-tillage since 1989, with preserved structure were collected in the layers of 0.00 to 0.10m and 0.10 to 0.20m depth. The samples (eight replicates were saturated in water and

  16. Acoustic rhinometry (AR): An Alternative Method to Image Nasal Airway Geometry

    DEFF Research Database (Denmark)

    Straszek, Sune; Pedersen, O.F.

      ACOUSTIC RHINOMETRY (AR): AN ALTERNATIVE METHOD TO IMAGE NASAL AIRWAY GEOMETRY.  INTRODUCTION AND BACKGROUND:  In human studies the acoustic reflection technique was first applied to describe the area-distance relationship of the lower airways, but later the acoustic reflection technique appeared...... to be of more use in the description of nasal cavity geometry. Applied to human subjects AR has been applied to monitor the effect of corrective surgery and mucosal effects of pharmacological interventions. In recent years, however, AR has found use also in pharmacological studies in animals ranging in size...

  17. Impact of adopting IFRS standard on the equity cost of brazilian open capital companies / Impacto da adoção do padrão IFRS no custo de capital próprio das empresas de capital aberto no Brasil

    Directory of Open Access Journals (Sweden)

    Rafael Confetti Gatsios

    2016-08-01

    por meio do Modelo CAPM (Capital Asset Pricing Model adaptado ao caso brasileiro. A metodologia utilizada foi a de análise de diferenças em diferenças, comparando os resultados de empresas que adotaram voluntariamente o padrão IFRS com empresas que adotaram o padrão IFRS após o período de adoção obrigatória. Síntese dos principais resultados: Os resultados indicam que a adoção do padrão IFRS não contribui para a redução do custo de capital próprio no Brasil. Principais considerações/ conclusões: Sugerindo assim que o processo de adoção do padrão internacional de contabilidade pode levar um maior tempo para impactar o custo de capital próprio das empresas brasileiras de capital aberto, uma vez que o impacto do padrão IFRS não está relacionado apenas com a adoção da norma, mas também com seu uso pelas empresas e usuários.

  18. Uma introdução ao capitalismo dirigido pelas finanças

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