WorldWideScience

Sample records for aberration correction algorithms

  1. Aberration Corrected Emittance Exchange

    CERN Document Server

    Nanni, Emilio A

    2015-01-01

    Full exploitation of emittance exchange (EEX) requires aberration-free performance of a complex imaging system including active radio-frequency (RF) elements which can add temporal distortions. We investigate the performance of an EEX line where the exchange occurs between two dimensions with normalized emittances which differ by orders of magnitude. The transverse emittance is exchanged into the longitudinal dimension using a double dog-leg emittance exchange setup with a 5 cell RF deflector cavity. Aberration correction is performed on the four most dominant aberrations. These include temporal aberrations that are corrected with higher order magnetic optical elements located where longitudinal and transverse emittance are coupled. We demonstrate aberration-free performance of emittances differing by 4 orders of magnitude, i.e. an initial transverse emittance of $\\epsilon_x=1$ pm-rad is exchanged with a longitudinal emittance of $\\epsilon_z=10$ nm-rad.

  2. A speed of sound aberration correction algorithm for curvilinear ultrasound transducers in ultrasound-based image-guided radiotherapy

    Science.gov (United States)

    Fontanarosa, Davide; Pesente, Silvia; Pascoli, Francesco; Ermacora, Denis; Abu Rumeileh, Imad; Verhaegen, Frank

    2013-03-01

    Conventional ultrasound (US) devices use the time of flight (TOF) of reflected US pulses to calculate distances inside the scanned tissues and thus create images. The speed of sound (SOS) is assumed to be constant in all human soft tissues at a generally accepted average value of 1540 m s-1. This assumption is a source of systematic errors up to several millimeters and of image distortion in quantitative US imaging. In this work, an extension of a method recently published by Fontanarosa et al (2011 Med. Phys. 38 2665-73) is presented: the aim is to correct SOS aberrations in three-dimensional (3D) US images in those cases where a spatially co-registered computerized tomography (CT) scan is also available; the algorithm is then applicable to a more general case where the lines of view (LOV) of the US device are not necessarily parallel and coplanar, thus allowing correction also for US transducers other than linear. The algorithm was applied on a multi-modality pelvic US phantom, scanned through three different liquid layers on top of the phantom with different SOS values; the results show that the correction restores a better match between the CT and the US images, reducing the differences to sub-millimeter agreement. Fifteen clinical cases of prostate cancer patients were also investigated: the SOS corrections of prostate centroids were on average +3.1 mm (max + 4.9 mm-min + 1.3 mm). This is in excellent agreement with reports in the literature on differences between measured prostate positions by US and other techniques, where often the discrepancy was attributed to other causes.

  3. Pulse compressor with aberration correction

    Energy Technology Data Exchange (ETDEWEB)

    Mankos, Marian [Electron Optica, Inc., Palo Alto, CA (United States)

    2015-11-30

    In this SBIR project, Electron Optica, Inc. (EOI) is developing an electron mirror-based pulse compressor attachment to new and retrofitted dynamic transmission electron microscopes (DTEMs) and ultrafast electron diffraction (UED) cameras for improving the temporal resolution of these instruments from the characteristic range of a few picoseconds to a few nanoseconds and beyond, into the sub-100 femtosecond range. The improvement will enable electron microscopes and diffraction cameras to better resolve the dynamics of reactions in the areas of solid state physics, chemistry, and biology. EOI’s pulse compressor technology utilizes the combination of electron mirror optics and a magnetic beam separator to compress the electron pulse. The design exploits the symmetry inherent in reversing the electron trajectory in the mirror in order to compress the temporally broadened beam. This system also simultaneously corrects the chromatic and spherical aberration of the objective lens for improved spatial resolution. This correction will be found valuable as the source size is reduced with laser-triggered point source emitters. With such emitters, it might be possible to significantly reduce the illuminated area and carry out ultrafast diffraction experiments from small regions of the sample, e.g. from individual grains or nanoparticles. During phase I, EOI drafted a set of candidate pulse compressor architectures and evaluated the trade-offs between temporal resolution and electron bunch size to achieve the optimum design for two particular applications with market potential: increasing the temporal and spatial resolution of UEDs, and increasing the temporal and spatial resolution of DTEMs. Specialized software packages that have been developed by MEBS, Ltd. were used to calculate the electron optical properties of the key pulse compressor components: namely, the magnetic prism, the electron mirror, and the electron lenses. In the final step, these results were folded

  4. Catadioptric aberration correction in cathode lens microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Tromp, R.M. [IBM T.J. Watson Research Center, PO Box 218, Yorktown Heights, NY 10598 (United States); Kamerlingh Onnes Laboratory, Leiden Institute of Physics, Niels Bohrweg 2, 2333 CA Leiden (Netherlands)

    2015-04-15

    In this paper I briefly review the use of electrostatic electron mirrors to correct the aberrations of the cathode lens objective lens in low energy electron microscope (LEEM) and photo electron emission microscope (PEEM) instruments. These catadioptric systems, combining electrostatic lens elements with a reflecting mirror, offer a compact solution, allowing simultaneous and independent correction of both spherical and chromatic aberrations. A comparison with catadioptric systems in light optics informs our understanding of the working principles behind aberration correction with electron mirrors, and may point the way to further improvements in the latter. With additional developments in detector technology, 1 nm spatial resolution in LEEM appears to be within reach. - Highlights: • The use of electron mirrors for aberration correction in LEEM/PEEM is reviewed. • A comparison is made with similar systems in light optics. • Conditions for 1 nm spatial resolution are discussed.

  5. Catadioptric aberration correction in cathode lens microscopy

    International Nuclear Information System (INIS)

    In this paper I briefly review the use of electrostatic electron mirrors to correct the aberrations of the cathode lens objective lens in low energy electron microscope (LEEM) and photo electron emission microscope (PEEM) instruments. These catadioptric systems, combining electrostatic lens elements with a reflecting mirror, offer a compact solution, allowing simultaneous and independent correction of both spherical and chromatic aberrations. A comparison with catadioptric systems in light optics informs our understanding of the working principles behind aberration correction with electron mirrors, and may point the way to further improvements in the latter. With additional developments in detector technology, 1 nm spatial resolution in LEEM appears to be within reach. - Highlights: • The use of electron mirrors for aberration correction in LEEM/PEEM is reviewed. • A comparison is made with similar systems in light optics. • Conditions for 1 nm spatial resolution are discussed

  6. Optical advantages of astigmatic aberration corrected heliostats

    Science.gov (United States)

    van Rooyen, De Wet; Schöttl, Peter; Bern, Gregor; Heimsath, Anna; Nitz, Peter

    2016-05-01

    Astigmatic aberration corrected heliostats adapt their shape in dependence of the incidence angle of the sun on the heliostat. Simulations show that this optical correction leads to a higher concentration ratio at the target and thus in a decrease in required receiver aperture in particular for smaller heliostat fields.

  7. Correcting the Chromatic Aberration in Barrel Distortion of Endoscopic Images

    Directory of Open Access Journals (Sweden)

    Y. M. Harry Ng

    2003-04-01

    Full Text Available Modern endoscopes offer physicians a wide-angle field of view (FOV for minimally invasive therapies. However, the high level of barrel distortion may prevent accurate perception of image. Fortunately, this kind of distortion may be corrected by digital image processing. In this paper we investigate the chromatic aberrations in the barrel distortion of endoscopic images. In the past, chromatic aberration in endoscopes is corrected by achromatic lenses or active lens control. In contrast, we take a computational approach by modifying the concept of image warping and the existing barrel distortion correction algorithm to tackle the chromatic aberration problem. In addition, an error function for the determination of the level of centroid coincidence is proposed. Simulation and experimental results confirm the effectiveness of our method.

  8. The correction of electron lens aberrations

    Energy Technology Data Exchange (ETDEWEB)

    Hawkes, P.W., E-mail: peter.hawkes@cemes.fr

    2015-09-15

    The progress of electron lens aberration correction from about 1990 onwards is chronicled. Reasonably complete lists of publications on this and related topics are appended. A present for Max Haider and Ondrej Krivanek in the year of their 65th birthdays. By a happy coincidence, this review was completed in the year that both Max Haider and Ondrej Krivanek reached the age of 65. It is a pleasure to dedicate it to the two leading actors in the saga of aberration corrector design and construction. They would both wish to associate their colleagues with such a tribute but it is the names of Haider and Krivanek (not forgetting Joachim Zach) that will remain in the annals of electron optics, next to that of Harald Rose. I am proud to know that both regard me as a friend as well as a colleague. - Highlights: • Geometrical aberration correction. • Chromatic aberration correction. • 50 pm resolution. • High-resolution electron energy-loss spectroscopy. • Extensive bibliographies.

  9. The correction of electron lens aberrations.

    Science.gov (United States)

    Hawkes, P W

    2015-09-01

    The progress of electron lens aberration correction from about 1990 onwards is chronicled. Reasonably complete lists of publications on this and related topics are appended. A present for Max Haider and Ondrej Krivanek in the year of their 65th birthdays. By a happy coincidence, this review was completed in the year that both Max Haider and Ondrej Krivanek reached the age of 65. It is a pleasure to dedicate it to the two leading actors in the saga of aberration corrector design and construction. They would both wish to associate their colleagues with such a tribute but it is the names of Haider and Krivanek (not forgetting Joachim Zach) that will remain in the annals of electron optics, next to that of Harald Rose. I am proud to know that both regard me as a friend as well as a colleague. PMID:26025209

  10. Environmental TEM in an Aberration Corrected Microscope

    DEFF Research Database (Denmark)

    Hansen, Thomas Willum; Wagner, Jakob Birkedal

    The increasing use of environmental transmission electron microscopy (ETEM) in materials science provides exciting new possibilities for investigating chemical reactions and understanding both the interaction of fast electrons with gas molecules and the effect of the presence of gas on high......‐resolution imaging. A gaseous atmosphere in the pole‐piece gap of the objective lens of the microscope alters both the incoming electron wave prior to interaction with the sample and the outgoing wave below the sample. Whereas conventional TEM samples are usually thin (below 10‐20 nm), the gas in the environmental......‐of‐the‐art aberration corrected TEMs provide electron micrographs with high spatial resolution. The apparent interpretability of such images encourages microscopists to analyze data more quantitatively. Such an analysis requires a detailed knowledge of the entire path and propagation of the electrons along...

  11. Temperature Corrected Bootstrap Algorithm

    Science.gov (United States)

    Comiso, Joey C.; Zwally, H. Jay

    1997-01-01

    A temperature corrected Bootstrap Algorithm has been developed using Nimbus-7 Scanning Multichannel Microwave Radiometer data in preparation to the upcoming AMSR instrument aboard ADEOS and EOS-PM. The procedure first calculates the effective surface emissivity using emissivities of ice and water at 6 GHz and a mixing formulation that utilizes ice concentrations derived using the current Bootstrap algorithm but using brightness temperatures from 6 GHz and 37 GHz channels. These effective emissivities are then used to calculate surface ice which in turn are used to convert the 18 GHz and 37 GHz brightness temperatures to emissivities. Ice concentrations are then derived using the same technique as with the Bootstrap algorithm but using emissivities instead of brightness temperatures. The results show significant improvement in the area where ice temperature is expected to vary considerably such as near the continental areas in the Antarctic, where the ice temperature is colder than average, and in marginal ice zones.

  12. On-line correction of aberrations in particle spectrographs

    International Nuclear Information System (INIS)

    A new method is presented that allows the reconstruction of trajectories and the on-line correction of residual aberrations that limit the resolution of particle spectrographs. Using a computed or fitted high order transfer map that describes the uncorrected aberrations of the spectrograph under consideration, it is possible to determine a pseudo transfer map that allows the computation of the corrected data of interest as well as the reconstructed trajectories in terms of position measurements in two planes near the focal plane. The technique is only limited by the accuracy of the position measurements and the accuracy of the transfer map. In practice the method can be expressed as an inversion of a pseudo transfer map and implemented in the differential algebraic framework. The method will be used to correct residual high aberrations in the S800 spectrograph which is under construction at the National Superconducting Cyclotron Laboratory at Michigan State University

  13. Double aberration correction in a low-energy electron microscope

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Th., E-mail: schmidtt@fhi-berlin.mpg.de [Fritz-Haber-Institut der Max-Planck-Gesellschaft, Faradayweg 6-8, D-14195 Berlin (Germany); Universitaet Wuerzburg, Experimentelle Physik II, Am Hubland, D-97074 Wuerzburg (Germany); Marchetto, H.; Levesque, P.L. [Fritz-Haber-Institut der Max-Planck-Gesellschaft, Faradayweg 6-8, D-14195 Berlin (Germany); Groh, U.; Maier, F. [Universitaet Wuerzburg, Experimentelle Physik II, Am Hubland, D-97074 Wuerzburg (Germany); Preikszas, D. [Technische Universitaet Darmstadt, Angewandte Physik, Hochschulstrasse 6, D-64289 Darmstadt (Germany); Carl Zeiss NTS GmbH, Carl-Zeiss-Strasse 56, D-73447 Oberkochen (Germany); Hartel, P.; Spehr, R. [Technische Universitaet Darmstadt, Angewandte Physik, Hochschulstrasse 6, D-64289 Darmstadt (Germany); Lilienkamp, G. [Technische Universitaet Clausthal, Physikalisches Institut, Leibnizstrasse 4, D-38678 (Germany); Engel, W. [Fritz-Haber-Institut der Max-Planck-Gesellschaft, Faradayweg 6-8, D-14195 Berlin (Germany); Fink, R. [Universitaet Erlangen-Nuernberg, Physikalische Chemie II, Egerlandstrasse 3, D-91058 Erlangen (Germany); Bauer, E. [Technische Universitaet Clausthal, Physikalisches Institut, Leibnizstrasse 4, D-38678 (Germany); Arizona State University, Department of Physics, Tempe, AZ 85287 (United States); Rose, H. [Technische Universitaet Darmstadt, Angewandte Physik, Hochschulstrasse 6, D-64289 Darmstadt (Germany); Umbach, E. [Universitaet Wuerzburg, Experimentelle Physik II, Am Hubland, D-97074 Wuerzburg (Germany); Freund, H.-J. [Fritz-Haber-Institut der Max-Planck-Gesellschaft, Faradayweg 6-8, D-14195 Berlin (Germany)

    2010-10-15

    The lateral resolution of a surface sensitive low-energy electron microscope (LEEM) has been improved below 4 nm for the first time. This breakthrough has only been possible by simultaneously correcting the unavoidable spherical and chromatic aberrations of the lens system. We present an experimental criterion to quantify the aberration correction and to optimize the electron optical system. The obtained lateral resolution of 2.6 nm in LEEM enables the first surface sensitive, electron microscopic observation of the herringbone reconstruction on the Au(1 1 1) surface.

  14. Adaptive temporal and wavefront aberration correction for ultrafast lasers with a membrane deformable mirror

    Science.gov (United States)

    Sherman, Leah Bruner

    Two adaptive optic systems for correction of either temporal phase error and wavefront errors for ultrafast pulses are demonstrated. These systems consists of a computer controlled micromachined membrane deformable mirror (MMDM) and a genetic learning algorithm (GA). Nonlinear excitation such as two-photon fluorescence or second harmonic generation are used as feedback to the GA to determine the appropriate correction to apply to the mirror. Two MMDMs are used, a 30 x 8 mm, 39 actuator linear MMDM for pulse-shaping applications and a 15 mm diameter, 37 actuator wavefront MMDM. Linear pre-compensation of self-phase modulation (SPM) was experimentally demonstrated utilizing the linear MMDM in a linear pulse-shaper for ultrafast pulses. The nonlinear nature of SPM makes arbitrary polynomial compensation necessary. Pre-compensation of SPM generated in an optical fiber by a 10 fs pulse reduced the pulse from 30fs to 20fs. We demonstrates adaptive correction with the wavefront MMDM by corrected for coma and astigmatism in a reflective multiphoton scanning microscope. An f1, parabola produces a very tight focus with no aberration when it is perfectly aligned. However, when beam scanning is used for two-dimensional imaging the image is severely aberrated. The MMDM and the GA are able to find the best possible wavefront for aberration correction for each scanning position. The horizontal scanning range was increased from 60 mum without the adaptive correction to 170 mum, ≈3 times the uncorrected scanning range, and the vertical scanning range was increased by a comparable amount. This resulted in an increase in scanning area of 9 times. The wavefront MMDM was also used for adaptive correction of spherical aberration from focusing from air, deep into a water-based sample. This depth-based aberration results from an index of refraction mismatch between the sample and the immersion medium of the objective and occurs regardless of beam scanning or sample scanning. By

  15. Adaptive, spatially-varying aberration correction for real-time holographic projectors.

    Science.gov (United States)

    Kaczorowski, Andrzej; Gordon, George S D; Wilkinson, Timothy D

    2016-07-11

    A method of generating an aberration- and distortion-free wide-angle holographically projected image in real time is presented. The target projector is first calibrated using an automated adaptive-optical mechanism. The calibration parameters are then fed into the hologram generation program, which applies a novel piece-wise aberration correction algorithm. The method is found to offer hologram generation times up to three orders of magnitude faster than the standard method. A projection of an aberration- and distortion-free image with a field of view of 90x45 degrees is demonstrated. The implementation on a mid-range GPU achieves high resolution at a frame rate up to 12fps. The presented methods are automated and can be performed on any holographic projector. PMID:27410846

  16. Correction for polychromatic aberration in computed tomography images

    International Nuclear Information System (INIS)

    A method and apparatus for correcting a computed tomography image for polychromatic aberration caused by the non-linear interaction (i.e. the energy dependent attenuation characteristics) of different body constituents, such as bone and soft tissue, with a polychromatic X-ray beam are described in detail. An initial image is conventionally computed from path measurements made as source and detector assembly scan a body section. In the improvement, each image element of the initial computed image representing attenuation is recorded in a store and is compared with two thresholds, one representing bone and the other soft tissue. Depending on the element value relative to the thresholds, a proportion of the respective constituent is allocated to that element location and corresponding bone and soft tissue projections are determined and stored. An error projection generator calculates projections of polychromatic aberration errors in the raw image data from recalled bone and tissue projections using a multidimensional polynomial function which approximates the non-linear interaction involved. After filtering, these are supplied to an image reconstruction computer to compute image element correction values which are subtracted from raw image element values to provide a corrected reconstructed image for display. (author)

  17. Transcranial phase aberration correction using beam simulations and MR-ARFI

    International Nuclear Information System (INIS)

    Purpose: Transcranial magnetic resonance-guided focused ultrasound surgery is a noninvasive technique for causing selective tissue necrosis. Variations in density, thickness, and shape of the skull cause aberrations in the location and shape of the focal zone. In this paper, the authors propose a hybrid simulation-MR-ARFI technique to achieve aberration correction for transcranial MR-guided focused ultrasound surgery. The technique uses ultrasound beam propagation simulations with MR Acoustic Radiation Force Imaging (MR-ARFI) to correct skull-caused phase aberrations. Methods: Skull-based numerical aberrations were obtained from a MR-guided focused ultrasound patient treatment and were added to all elements of the InSightec conformal bone focused ultrasound surgery transducer during transmission. In the first experiment, the 1024 aberrations derived from a human skull were condensed into 16 aberrations by averaging over the transducer area of 64 elements. In the second experiment, all 1024 aberrations were applied to the transducer. The aberrated MR-ARFI images were used in the hybrid simulation-MR-ARFI technique to find 16 estimated aberrations. These estimated aberrations were subtracted from the original aberrations to result in the corrected images. Each aberration experiment (16-aberration and 1024-aberration) was repeated three times. Results: The corrected MR-ARFI image was compared to the aberrated image and the ideal image (image with zero aberrations) for each experiment. The hybrid simulation-MR-ARFI technique resulted in an average increase in focal MR-ARFI phase of 44% for the 16-aberration case and 52% for the 1024-aberration case, and recovered 83% and 39% of the ideal MR-ARFI phase for the 16-aberrations and 1024-aberration case, respectively. Conclusions: Using one MR-ARFI image and noa priori information about the applied phase aberrations, the hybrid simulation-MR-ARFI technique improved the maximum MR-ARFI phase of the beam's focus

  18. Transcranial phase aberration correction using beam simulations and MR-ARFI

    Energy Technology Data Exchange (ETDEWEB)

    Vyas, Urvi, E-mail: urvi.vyas@gmail.com; Kaye, Elena; Pauly, Kim Butts [Department of Radiology, Stanford University, Stanford, California 94305 (United States)

    2014-03-15

    Purpose: Transcranial magnetic resonance-guided focused ultrasound surgery is a noninvasive technique for causing selective tissue necrosis. Variations in density, thickness, and shape of the skull cause aberrations in the location and shape of the focal zone. In this paper, the authors propose a hybrid simulation-MR-ARFI technique to achieve aberration correction for transcranial MR-guided focused ultrasound surgery. The technique uses ultrasound beam propagation simulations with MR Acoustic Radiation Force Imaging (MR-ARFI) to correct skull-caused phase aberrations. Methods: Skull-based numerical aberrations were obtained from a MR-guided focused ultrasound patient treatment and were added to all elements of the InSightec conformal bone focused ultrasound surgery transducer during transmission. In the first experiment, the 1024 aberrations derived from a human skull were condensed into 16 aberrations by averaging over the transducer area of 64 elements. In the second experiment, all 1024 aberrations were applied to the transducer. The aberrated MR-ARFI images were used in the hybrid simulation-MR-ARFI technique to find 16 estimated aberrations. These estimated aberrations were subtracted from the original aberrations to result in the corrected images. Each aberration experiment (16-aberration and 1024-aberration) was repeated three times. Results: The corrected MR-ARFI image was compared to the aberrated image and the ideal image (image with zero aberrations) for each experiment. The hybrid simulation-MR-ARFI technique resulted in an average increase in focal MR-ARFI phase of 44% for the 16-aberration case and 52% for the 1024-aberration case, and recovered 83% and 39% of the ideal MR-ARFI phase for the 16-aberrations and 1024-aberration case, respectively. Conclusions: Using one MR-ARFI image and noa priori information about the applied phase aberrations, the hybrid simulation-MR-ARFI technique improved the maximum MR-ARFI phase of the beam's focus.

  19. Influence of Misalignment on High-Order Aberration Correction for Normal Human Eyes

    Institute of Scientific and Technical Information of China (English)

    ZHAO Hao-Xin; XU Bing; XUE Li-Xia; DAI Yun; LIU Qian; RAO Xue-Jun

    2008-01-01

    @@ Although a compensation device can correct aberrations of human eyes, the effect will be degraded by its misalignment, especially for high-order aberration correction. We caJculate the positioning tolerance of correction device for high-order aberrations, and within what degree the correcting effect is better than low-order aberration (defocus and astigmatism) correction. With fixed certain misalignment within the positioning tolerance, we calculate the residual wavefront rms aberration of the first-6 to first-35 terms along with the 3rd-5th terms of aberrations corrected, and the combined first-13 terms of aberrations are also studied under the same quantity of misalignment. However, the correction effect of high-order aberrations does not meliorate along with the increase of the high-order terms under some misalignment, moreover, some simple combined terms correction can achieve similar result as complex combinations. These results suggest that it is unnecessary to correct too much the terms of high-order aberrations which are diffcult to accomplish in practice, and gives confdence to correct high-order aberrations out of the laboratory.

  20. High order aberration and straylight evaluation after cataract surgery with implantation of an aspheric,aberration correcting monofocal intraocular lens

    Institute of Scientific and Technical Information of China (English)

    Florian; T; A; Kretz; Tamer; Tandogan; Ramin; Khoramnia; Gerd; U; Auffarth

    2015-01-01

    ·AIM: To evaluate the quality of vision in respect to high order aberrations and straylight perception after implantation of an aspheric, aberration correcting,monofocal intraocular lens(IOL).·METHODS: Twenty-one patients(34 eyes) aged 50 to83 y underwent cataract surgery with implantation of an aspheric, aberration correcting IOL(Tecnis ZCB00,Abbott Medical Optics). Three months after surgery they were examined for uncorrected(UDVA) and corrected distance visual acuity(CDVA), contrast sensitivity(CS)under photopic and mesopic conditions with and without glare source, ocular high order aberrations(HOA, Zywave II) and retinal straylight(C-Quant).· RESULTS: Postoperatively, patients achieved a postoperative CDVA of 0.0 log MAR or better in 97.1% of eyes. Mean values of high order abberations were +0.02±0.27(primary coma components) and-0.04 ±0.16(spherical aberration term). Straylight values of the C-Quant were 1.35±0.44 log which is within normal range of age matched phakic patients. The CS measurements under mesopic and photopic conditions in combination with and without glare did not show any statistical significance in the patient group observed(P ≥0.28).· CONCLUSION: The implantation of an aspherical aberration correcting monofocal IOL after cataractsurgery resulted in very low residual higher order aberration(HOA) and normal straylight.

  1. Studying Atomic Structures by Aberration-Corrected Transmission Electron Microscopy

    Science.gov (United States)

    Urban, Knut W.

    2008-07-01

    Seventy-five years after its invention, transmission electron microscopy has taken a great step forward with the introduction of aberration-corrected electron optics. An entirely new generation of instruments enables studies in condensed-matter physics and materials science to be performed at atomic-scale resolution. These new possibilities are meeting the growing demand of nanosciences and nanotechnology for the atomic-scale characterization of materials, nanosynthesized products and devices, and the validation of expected functions. Equipped with electron-energy filters and electron-energy loss spectrometers, the new instruments allow studies not only of structure but also of elemental composition and chemical bonding. The energy resolution is about 100 milli electron volts, and the accuracy of spatial measurements has reached a few picometers. However, understanding the results is generally not straightforward and only possible with extensive quantum-mechanical computer calculations.

  2. EVALUATION OF CORRECTION METHODS OF CHROMATIC ABERRATION IN DIGITAL CAMERA IMAGES

    OpenAIRE

    Matsuoka, R; Asonuma, K.; Takahashi, G; Danjo, T.; Hirana, K.

    2012-01-01

    This paper reports an experiment conducted to evaluate correction methods of chromatic aberrations in images acquired by a nonmetric digital camera. The chromatic aberration correction methods evaluated in the experiment are classified into two kinds. One is the method to correct image coordinates by using camera calibration results of color-separated images. The other is the method based on the assumption that the magnitude of chromatic aberrations can be expressed by a function of ...

  3. Vision improvement by correcting higher-order aberrations with customized soft contact lenses in keratoconic eyes

    Science.gov (United States)

    Sabesan, Ramkumar; Jeong, Tae Moon; Carvalho, Luis; Cox, Ian G.; Williams, David R.; Yoon, Geunyoung

    2007-04-01

    Higher-order aberration correction in abnormal eyes can result in significant vision improvement, especially in eyes with abnormal corneas. Customized optics such as phase plates and customized contact lenses are one of the most practical, nonsurgical ways to correct these ocular higher-order aberrations. We demonstrate the feasibility of correcting higher-order aberrations and improving visual performance with customized soft contact lenses in keratoconic eyes while compensating for the static decentration and rotation of the lens. A reduction of higher-order aberrations by a factor of 3 on average was obtained in these eyes. The higher-order aberration correction resulted in an average improvement of 2.1 lines in visual acuity over the conventional correction of defocus and astigmatism alone.

  4. Smart microscope: an adaptive optics learning system for aberration correction in multiphoton confocal microscopy.

    Science.gov (United States)

    Albert, O; Sherman, L; Mourou, G; Norris, T B; Vdovin, G

    2000-01-01

    Off-axis aberrations in a beam-scanning multiphoton confocal microscope are corrected with a deformable mirror. The optimal mirror shape for each pixel is determined by a genetic learning algorithm, in which the second-harmonic or two-photon fluorescence signal from a reference sample is maximized. The speed of the convergence is improved by use of a Zernike polynomial basis for the deformable mirror shape. This adaptive optical correction scheme is implemented in an all-reflective system by use of extremely short (10-fs) optical pulses, and it is shown that the scanning area of an f:1 off-axis parabola can be increased by nine times with this technique. PMID:18059779

  5. Correction of chromatic aberrations at television registration of image through protective viewing systems

    Science.gov (United States)

    Kulyas, Oleg L.; Nikitin, Konstantin A.

    2016-03-01

    Ways of chromatic aberration in images are examined and analyzed which are generated at television supervision through protective glasses of a considerable thickness. The results of experimental check up of the given method of correction is introduced and described.

  6. Correction of Optical Aberrations in Elliptic Neutron Guides

    CERN Document Server

    Bentley, Phillip M; Andersen, Ken H; Rodriguez, Damian Martin; Mildner, David F R

    2012-01-01

    Modern, nonlinear ballistic neutron guides are an attractive concept in neutron beam delivery and instrumentation, because they offer increased performance over straight or linearly tapered guides. However, like other ballistic geometries they have the potential to create significantly non-trivial instrumental resolution functions. We address the source of the most prominent optical aberration, namely coma, and we show that for extended sources the off-axis rays have a different focal length from on-axis rays, leading to multiple reflections in the guide system. We illustrate how the interplay between coma, sources of finite size, and mirrors with non-perfect reflectivity can therefore conspire to produce uneven distributions in the neutron beam divergence, the source of complicated resolution functions. To solve these problems, we propose a hybrid elliptic-parabolic guide geometry. Using this new kind of neutron guide shape, it is possible to condition the neutron beam and remove almost all of the aberration...

  7. Design of macro-filter-lens with simultaneous chromatic and geometric aberration correction.

    Science.gov (United States)

    Prasad, Dilip K; Brown, Michael S

    2014-01-01

    A macro-filter-lens design that can correct for chromatic and geometric aberrations simultaneously while providing for a long focal length is presented. The filter is easy to fabricate since it involves two spherical surfaces and a planar surface. Chromatic aberration correction is achieved by making all the rays travel the same optical distance inside the filter element (negative meniscus). Geometric aberration is corrected for by the lens element (plano-convex), which makes the output rays parallel to the optic axis. This macro-filter-lens design does not need additional macro lenses and it provides an inexpensive and optically good (aberration compensated) solution for macro imaging of objects not placed close to the camera.

  8. AO-OCT for in vivo mouse retinal imaging: Application of adaptive lens in wavefornt sensorless aberration correction

    Science.gov (United States)

    Bonora, Stefano; Jian, Yifan; Pugh, Edward N.; Sarunic, Marinko V.; Zawadzki, Robert J.

    2014-03-01

    We demonstrate Adaptive optics - Optical Coherence Tomography (OCT) with modal sensorless Adaptive Optics correction with the use of novel Adaptive Lens (AL) applied for in-vivo imaging of mouse retinas. The AL can generate low order aberrations: defocus, astigmatism, coma and spherical aberration that were used in an adaptive search algorithm. Accelerated processing of the OCT data with a Graphic Processing Unit (GPU) permitted real time extraction of image projection total intensity for arbitrarily selected retinal depth plane to be optimized. Wavefront sensorless control is a viable option for imaging biological structures for which AOOCT cannot establish a reliable wavefront that could be corrected by wavefront corrector. Image quality improvements offered by adaptive lens with sensorless AO-OCT was evaluated on in vitro samples followed by mouse retina data acquired in vivo.

  9. Correction of optical aberrations in elliptic neutron guides

    Energy Technology Data Exchange (ETDEWEB)

    Bentley, Phillip M., E-mail: phillip.bentley@esss.se [Australian Nuclear Science and Technology Organisation (ANSTO), Locked Bag 2001, Kirrawee DC, NSW 2232 (Australia); European Spallation Source ESS AB, Box 176, 221 00 Lund (Sweden); Kennedy, Shane J. [Australian Nuclear Science and Technology Organisation (ANSTO), Locked Bag 2001, Kirrawee DC, NSW 2232 (Australia); Andersen, Ken H. [European Spallation Source ESS AB, Box 176, 221 00 Lund (Sweden); Martin Rodriguez, Damian [Juelich Centre for Neutron Science, Forschungszentrum Juelich GmbH, 52425 Juelich (Germany); Mildner, David F.R. [National Institute of Standards and Technology, Gaithersburg, MD 20899 (United States)

    2012-11-21

    Modern, nonlinear ballistic neutron guides are an attractive concept in neutron beam delivery and instrumentation because they offer increased performance over straight or linearly tapered guides. However, like other ballistic geometries they have the potential to create significantly non-trivial instrumental resolution functions. We address the source of the most prominent optical aberration, namely coma, and we show that for extended sources the off-axis rays have a different focal length from on-axis rays, leading to multiple reflections in the guide system. We illustrate how the interplay between coma, sources of finite size, and mirrors with non-perfect reflectivity can therefore conspire to produce uneven distributions in the neutron beam divergence, a source of complicated resolution functions. To solve these problems, we propose a hybrid elliptic-parabolic guide geometry. Using this new kind of neutron guide shape, it is possible to condition the neutron beam and remove almost all of the aberrations, whilst providing the same performance in beam current as a standard elliptic neutron guide. We highlight the positive implications for neutron scattering instruments that this new shape can bring.

  10. Environmental Transmission Electron Microscopy in an Aberration-Corrected Environment

    DEFF Research Database (Denmark)

    Hansen, Thomas W.; Wagner, Jakob B.

    2012-01-01

    The increasing use of environmental transmission electron microscopy (ETEM) in materials science provides exciting new possibilities for investigating chemical reactions and understanding both the interaction of fast electrons with gas molecules and the effect of the presence of gas on high......-resolution imaging. A gaseous atmosphere in the pole-piece gap of the objective lens of the microscope alters both the incoming electron wave prior to interaction with the sample and the outgoing wave below the sample. Whereas conventional TEM samples are usually thin (below 100 nm), the gas in the environmental...... cell fills the entire gap between the pole pieces and is thus not spatially localized. By using an FEI Titan environmental transmission electron microscope equipped with a monochromator and an aberration corrector on the objective lens, we have investigated the effects on imaging and spectroscopy...

  11. Correcting for color crosstalk and chromatic aberration in multicolor particle shadow velocimetry

    International Nuclear Information System (INIS)

    Color crosstalk and chromatic aberration can bias estimates of fluid velocity measured by color particle shadow velocimetry (CPSV), using multicolor illumination and a color camera. This article describes corrections to remove these bias errors, and their evaluation. Color crosstalk removal is demonstrated with linear unmixing. It is also shown that chromatic aberrations may be removed using either scale calibration, or by processing an image illuminated by all colors simultaneously. CPSV measurements of a fully developed turbulent pipe flow of glycerin were conducted. Corrected velocity statistics from these measurements were compared to both single-color PSV and LDV measurements and showed excellent agreement to fourth-order, to well into the viscous sublayer. Recommendations for practical assessment and correction of color aberration and color crosstalk are discussed. (paper)

  12. Transmissive liquid-crystal device correcting primary coma aberration and astigmatism in laser scanning microscopy

    Science.gov (United States)

    Tanabe, Ayano; Hibi, Terumasa; Ipponjima, Sari; Matsumoto, Kenji; Yokoyama, Masafumi; Kurihara, Makoto; Hashimoto, Nobuyuki; Nemoto, Tomomi

    2016-03-01

    Laser scanning microscopy allows 3D cross-sectional imaging inside biospecimens. However, certain aberrations produced can degrade the quality of the resulting images. We previously reported a transmissive liquid-crystal device that could compensate for the predominant spherical aberrations during the observations, particularly in deep regions of the samples. The device, inserted between the objective lens and the microscope revolver, improved the image quality of fixed-mouse-brain slices that were observed using two-photon excitation laser scanning microscopy, which was originally degraded by spherical aberration. In this study, we developed a transmissive device that corrects primary coma aberration and astigmatism, motivated by the fact that these asymmetric aberrations can also often considerably deteriorate image quality, even near the sample surface. The device's performance was evaluated by observing fluorescent beads using single-photon excitation laser scanning microscopy. The fluorescence intensity in the image of the bead under a cover slip tilted in the y-direction was increased by 1.5 times after correction by the device. Furthermore, the y- and z-widths of the imaged bead were reduced to 66% and 65%, respectively. On the other hand, for the imaged bead sucked into a glass capillary in the longitudinal x-direction, correction with the device increased the fluorescence intensity by 2.2 times compared to that of the aberrated image. In addition, the x-, y-, and z-widths of the bead image were reduced to 75%, 53%, and 40%, respectively. Our device successfully corrected several asymmetric aberrations to improve the fluorescent signal and spatial resolution, and might be useful for observing various biospecimens.

  13. Brief history of the Cambridge STEM aberration correction project and its progeny.

    Science.gov (United States)

    Brown, L Michael; Batson, Philip E; Dellby, Niklas; Krivanek, Ondrej L

    2015-10-01

    We provide a brief history of the project to correct the spherical aberration of the scanning transmission electron microscope (STEM) that started in Cambridge (UK) and continued in Kirkland (WA, USA), Yorktown Heights (NY, USA), and other places. We describe the project in the full context of other aberration correction research and related work, partly in response to the incomplete context presented in the paper "In quest of perfection in electron optics: A biographical sketch of Harald Rose on the occasion of his 80th birthday", recently published in Ultramicroscopy.

  14. Conformal optical design with combination of static and dynamic aberration corrections

    Institute of Scientific and Technical Information of China (English)

    Li Yan; Li Lin; Huang Yi-Fan; Liu Jia-Guo

    2009-01-01

    Conformal domes that are shaped to meet aerodynamic requirements can increase range and speed for the host platform. Because these domes typically deviate greatly from spherical surface descriptions, a variety of aberrations are induced which vary with the field-of-regard (FOR) angle. A system for correcting optical aberrations created by a conformal dome has an outer surface and an inner surface. Optimizing the inner surface is regard as static aberration correction. A deformable mirror is placed at the position of the secondary mirror in the two-mirror all reflective imaging system, which is the dynamic aberration correction. An ellipsoidal MgF2 conformal dome with a fineness ratio of 1.0 is designed as an example. The FOR angle is 00°-30°, and the design wavelength is 4 μm. After the optimization at 7zoom positions by using the design tools Code V, the root-mean-square (RMS) spot size is reduced to approximately 0.99 to 1.48 times the diffraction limit. The design results show that the performances of the conformal optical systems can be greatly improved by the combination of the static correction and the dynamic correction.

  15. Exploring the depth range for three-dimensional laser machining with aberration correction.

    Science.gov (United States)

    Salter, P S; Baum, M; Alexeev, I; Schmidt, M; Booth, M J

    2014-07-28

    The spherical aberration generated when focusing from air into another medium limits the depth at which ultrafast laser machining can be accurately maintained. We investigate how the depth range may be extended using aberration correction via a liquid crystal spatial light modulator (SLM), in both single point and parallel multi-point fabrication in fused silica. At a moderate numerical aperture (NA = 0.5), high fidelity fabrication with a significant level of parallelisation is demonstrated at the working distance of the objective lens, corresponding to a depth in the glass of 2.4 mm. With a higher numerical aperture (NA = 0.75) objective lens, single point fabrication is demonstrated to a depth of 1 mm utilising the full NA, and deeper with reduced NA, while maintaining high repeatability. We present a complementary theoretical model that enables prediction of the effectiveness of SLM based correction for different aberration magnitudes.

  16. Non-common path aberration correction in an adaptive optics scanning ophthalmoscope.

    Science.gov (United States)

    Sulai, Yusufu N; Dubra, Alfredo

    2014-09-01

    The correction of non-common path aberrations (NCPAs) between the imaging and wavefront sensing channel in a confocal scanning adaptive optics ophthalmoscope is demonstrated. NCPA correction is achieved by maximizing an image sharpness metric while the confocal detection aperture is temporarily removed, effectively minimizing the monochromatic aberrations in the illumination path of the imaging channel. Comparison of NCPA estimated using zonal and modal orthogonal wavefront corrector bases provided wavefronts that differ by ~λ/20 in root-mean-squared (~λ/30 standard deviation). Sequential insertion of a cylindrical lens in the illumination and light collection paths of the imaging channel was used to compare image resolution after changing the wavefront correction to maximize image sharpness and intensity metrics. Finally, the NCPA correction was incorporated into the closed-loop adaptive optics control by biasing the wavefront sensor signals without reducing its bandwidth.

  17. Aberration-corrected imaging of active sites on industrial catalyst nanoparticles

    DEFF Research Database (Denmark)

    Gontard, Lionel Cervera; Chang, L-Y; Hetherington, CJD;

    2007-01-01

    Picture perfect: Information about the local topologies of active sites on commercial nanoparticles can be gained with atomic resolution through spherical-aberration-corrected transmission electron microscopy (TEM). A powder of Pt nanoparticles on carbon black was examined with two advanced TEM t...

  18. A method to design aspheric spectacles for correction of high-order aberrations of human eye

    Institute of Scientific and Technical Information of China (English)

    LI Rui; WANG ZhaoQi; LIU YongJi; MU GuoGuang

    2012-01-01

    Aiming at the correction of high-order aberrations of human eye with spectacles,a design method of aspheric spectacles is proposed based on the eye's wavefront aberrations data.Regarding the eyeball and the spectacles as a whole system-the lens-eye system-the surface profiles of the spectacles are achieved by optimization procedure of lens design.Different from the conventional optometry,in which the refraction prescription is acquired with a visual chart,the design takes into account the two aspects of actual human viewing,eyeball rolling and certain distinct viewing field.The rotation angle of eyeball is set to be ±20° as wearing spectacles,and the field of view is set to be ∧7° which is especially important as watching screen display.The individual eye model is constructed as the main part of the lens-eye system.The Liou eye model is modified by sticking a thin meniscus lens to the crystalline lens.Then the defocus of the individual eye is transferred to the front surface of the meniscus lens,and the astigmatism and high-order aberrations are transferred to the front surface of the cornea.50 eyes are involved in this research,among which 36 eyes have good enough visual performance already after sphero-cylindrical correction.10 eyes have distinct improvement in vision and 4 eyes have no visual improvement by further aspheric correction.6 typical subject eyes are selected for the aberrations analysis and the spectacles design in this paper.It is shown that the validity of visual correction of aspheric lens depends on the characteristics of the eye's wavefront aberrations,and it is effective for the eye with larger astigmatism or spherical aberration.Compared with sphero-cylindrical correction only,the superiority taken by the aspheric correction is mainly on the improvement of MTF at a larger field of view.For the best aspheric correction,the MTF values increase by 18.87%,38.34%,44.36%,51.29% and 57.32% at the spatial frequencies of 40

  19. Chromosome aberrations, micronucleus and sperm head abnormalities in mice treated with natamycin, [corrected] a food preservative.

    Science.gov (United States)

    Rasgele, Pinar Goc; Kaymak, Fisun

    2010-03-01

    Natamycin [corrected] is used as preservative in foods. The genotoxic effects of the food preservative natamycin [corrected] were evaluated using chromosome aberrations and micronucleus test in bone marrow cells and sperm head abnormality assays in mice. Blood samples were taken from mice and levels of total testosterone in serum were also determined. Natamycin [corrected] was intraperitoneally (ip) injected at 200, 400 and 800 mg/kg. Natamycin [corrected] did not induce chromosome aberrations but significantly increased the number of micronucleated polychromatic erythrocytes in bone marrow and sperm head abnormalities at all concentrations and treatment periods. It also decreased MI at all concentrations for 6, 12 and 24h treatment periods. Natamycin [corrected] decreased PCE/NCE ratio at all concentrations for 48h in female mice, for 24 and 48h treatment periods in male mice. At the 800 mg/kg concentration, natamycin [corrected] decreased PCE/NCE ratio for 24 and 72h in female mice. A dose dependent increase was observed in the percentage of sperm head abnormalities. The levels of serum testosterone decreased dose-dependently. The obtained results indicate that natamycin [corrected] is not clastogenic, but it is aneugenic in mice bone marrow and it is a potential germ cell mutagen in sperm cells.

  20. Optimizing wavefront-guided corrections for highly aberrated eyes in the presence of registration uncertainty

    OpenAIRE

    Shi, Yue; Queener, Hope M.; Marsack, Jason D.; Ravikumar, Ayeswarya; Bedell, Harold E.; Applegate, Raymond A.

    2013-01-01

    Dynamic registration uncertainty of a wavefront-guided correction with respect to underlying wavefront error (WFE) inevitably decreases retinal image quality. A partial correction may improve average retinal image quality and visual acuity in the presence of registration uncertainties. The purpose of this paper is to (a) develop an algorithm to optimize wavefront-guided correction that improves visual acuity given registration uncertainty and (b) test the hypothesis that these corrections pro...

  1. A proposal for the holographic correction of incoherent aberrations by tilted reference waves

    Energy Technology Data Exchange (ETDEWEB)

    Röder, Falk, E-mail: Falk.Roeder@Triebenberg.de; Lubk, Axel

    2015-05-15

    The recently derived general transfer theory for off-axis electron holography provides a new approach for reconstructing the electron wave beyond the conventional sideband information limit. Limited ensemble coherence of the electron beam between object and reference area leads to an attenuation of spatial frequencies of the object exit wave in the presence of aberrations of the objective lens. Concerted tilts of the reference wave under the condition of an invariant object exit wave are proposed to diminish the aberration impact on spatial frequencies even beyond the sideband information limit allowing its transfer with maximum possible contrast. In addition to the theoretical considerations outlined in detail, an experimental proof-of-principle is presented. A fully controlled tilt of the reference wave, however, remains as a promising task for the future. The use of a hologram series with varying reference wave tilt is considered for linearly synthesizing an effective aperture for the transfer into the sideband with broader bandwidth compared to conventional off-axis electron holography allowing us to correct the incoherent aberrations in transmission electron microscopy. Furthermore, tilting a reference wave with respect to a plane wave is expected to be an alternative way for measuring the coherent and incoherent aberrations of a transmission electron microscope. The capability of tilting the reference wave is expected to be beneficial for improving the signal-to-noise ratio in dark-field off-axis electron holography as well. - Highlights: • We examine the use of tilted reference waves in off-axis electron holography. • Generalized holographic transfer theory reveals a selective filtering effect. • We propose the correction of incoherent aberrations by series acquisitions. • For a proof-of-principle, we employ a crystal for tilting the reference wave.

  2. A proposal for the holographic correction of incoherent aberrations by tilted reference waves

    International Nuclear Information System (INIS)

    The recently derived general transfer theory for off-axis electron holography provides a new approach for reconstructing the electron wave beyond the conventional sideband information limit. Limited ensemble coherence of the electron beam between object and reference area leads to an attenuation of spatial frequencies of the object exit wave in the presence of aberrations of the objective lens. Concerted tilts of the reference wave under the condition of an invariant object exit wave are proposed to diminish the aberration impact on spatial frequencies even beyond the sideband information limit allowing its transfer with maximum possible contrast. In addition to the theoretical considerations outlined in detail, an experimental proof-of-principle is presented. A fully controlled tilt of the reference wave, however, remains as a promising task for the future. The use of a hologram series with varying reference wave tilt is considered for linearly synthesizing an effective aperture for the transfer into the sideband with broader bandwidth compared to conventional off-axis electron holography allowing us to correct the incoherent aberrations in transmission electron microscopy. Furthermore, tilting a reference wave with respect to a plane wave is expected to be an alternative way for measuring the coherent and incoherent aberrations of a transmission electron microscope. The capability of tilting the reference wave is expected to be beneficial for improving the signal-to-noise ratio in dark-field off-axis electron holography as well. - Highlights: • We examine the use of tilted reference waves in off-axis electron holography. • Generalized holographic transfer theory reveals a selective filtering effect. • We propose the correction of incoherent aberrations by series acquisitions. • For a proof-of-principle, we employ a crystal for tilting the reference wave

  3. Optimization of neutron monitor data correction algorithms

    Energy Technology Data Exchange (ETDEWEB)

    Paschalis, P. [Nuclear and Particle Physics Section, Physics Department, National and Kapodistrian University of Athens, Zografos 15783, Athens (Greece); Mavromichalaki, H., E-mail: emavromi@phys.uoa.gr [Nuclear and Particle Physics Section, Physics Department, National and Kapodistrian University of Athens, Zografos 15783, Athens (Greece)

    2013-06-21

    Nowadays, several neutron monitor stations worldwide, broadcast their cosmic ray data in real time, in order for the scientific community to be able to use these measurements immediately. In parallel, the development of the Neutron Monitor Database (NMDB; (http://www.nmdb.eu)) which collects all the high resolution real time measurements, allows the implementation of various applications and services by using these data instantly. Therefore, it is obvious that the need for high quality real time data is imperative. The quality of the data is handled by different correction algorithms that filter the real time measurements for undesired instrumental variations. In this work, an optimization of the Median Editor that is currently mainly applied to the neutron monitor data and the recently proposed ANN algorithm based on neural networks is presented. This optimization leads to the implementation of the Median Editor Plus and the ANN Plus algorithms. A direct comparison of these algorithms with the newly appeared Edge Editor is performed and the results are presented.

  4. Correction of axial chromatic aberrations in confocal Raman microspectroscopic measurements of a single microbial spore.

    Science.gov (United States)

    Lasch, Peter; Hermelink, Antje; Naumann, Dieter

    2009-06-01

    Herein we describe a strategy for correcting the longitudinal or axial component of chromatic aberration in confocal Raman microspectroscopy. The method is based on measuring a vertical series of confocal Raman sections of samples by a high numerical aperture Raman microscope. Using the known characteristics of the wavelength-dependent focal shift of the optical system, the Raman intensities can be corrected to allow the rearrangement of Raman data from different focal planes. In the present study the computational correction routine was applied to an experimental data set of 4-dimensional (xyz spatial and the spectral dimension) confocal Raman spectra collected from single spores of Bacillus cereus. After correcting the axial component of the chromatic aberration, univariate and multivariate spectral parameters were obtained and used in the following for 3D segmentation and volume rendering on the basis of the structural and compositional information contained in the Raman spectra of the spore. Using univariate Raman intensities from defined functional group frequencies or k-means cluster membership values as a multivariate parameter for volume rendering, we demonstrate a high degree of correlation between confocal Raman microspectroscopy and the spores' morphology. In this paper we will also present cluster mean spectra which will be discussed in light of the presence of proteins and Ca-DPA, a calcium chelate of dipicolinic acid in the spore. PMID:19475143

  5. Numerical correction of anti-symmetric aberrations in single HRTEM images of weakly scattering 2D-objects

    Energy Technology Data Exchange (ETDEWEB)

    Lehtinen, Ossi, E-mail: ossi.lehtinen@gmail.com [Central Facility for Electron Microscopy, Group of Electron Microscopy of Materials Science, University of Ulm, 89081 Ulm (Germany); Geiger, Dorin; Lee, Zhongbo [Central Facility for Electron Microscopy, Group of Electron Microscopy of Materials Science, University of Ulm, 89081 Ulm (Germany); Whitwick, Michael Brian; Chen, Ming-Wei; Kis, Andras [Electrical Engineering Institute, Ecole Polytechnique Federale de Lausanne (EPFL), CH-1015 Lausanne (Switzerland); Kaiser, Ute [Central Facility for Electron Microscopy, Group of Electron Microscopy of Materials Science, University of Ulm, 89081 Ulm (Germany)

    2015-04-15

    Here, we present a numerical post-processing method for removing the effect of anti-symmetric residual aberrations in high-resolution transmission electron microscopy (HRTEM) images of weakly scattering 2D-objects. The method is based on applying the same aberrations with the opposite phase to the Fourier transform of the recorded image intensity and subsequently inverting the Fourier transform. We present the theoretical justification of the method, and its verification based on simulated images in the case of low-order anti-symmetric aberrations. Ultimately the method is applied to experimental hardware aberration-corrected HRTEM images of single-layer graphene and MoSe{sub 2} resulting in images with strongly reduced residual low-order aberrations, and consequently improved interpretability. Alternatively, this method can be used to estimate by trial and error the residual anti-symmetric aberrations in HRTEM images of weakly scattering objects.

  6. Quantum computations: algorithms and error correction

    Science.gov (United States)

    Kitaev, A. Yu

    1997-12-01

    Contents §0. Introduction §1. Abelian problem on the stabilizer §2. Classical models of computations2.1. Boolean schemes and sequences of operations2.2. Reversible computations §3. Quantum formalism3.1. Basic notions and notation3.2. Transformations of mixed states3.3. Accuracy §4. Quantum models of computations4.1. Definitions and basic properties4.2. Construction of various operators from the elements of a basis4.3. Generalized quantum control and universal schemes §5. Measurement operators §6. Polynomial quantum algorithm for the stabilizer problem §7. Computations with perturbations: the choice of a model §8. Quantum codes (definitions and general properties)8.1. Basic notions and ideas8.2. One-to-one codes8.3. Many-to-one codes §9. Symplectic (additive) codes9.1. Algebraic preparation9.2. The basic construction9.3. Error correction procedure9.4. Torus codes §10. Error correction in the computation process: general principles10.1. Definitions and results10.2. Proofs §11. Error correction: concrete procedures11.1. The symplecto-classical case11.2. The case of a complete basis Bibliography

  7. Simultaneous fluorescence and high-resolution bright-field imaging with aberration correction over a wide field-of-view with Fourier ptychographic microscopy (FPM) (Conference Presentation)

    Science.gov (United States)

    Chung, Jaebum; Kim, Jinho; Ou, Xiaoze; Horstmeyer, Roarke; Yang, Changhuei

    2016-03-01

    We present a method to acquire both fluorescence and high-resolution bright-field images with correction for the spatially varying aberrations over a microscope's wide field-of-view (FOV). First, the procedure applies Fourier ptychographic microscopy (FPM) to retrieve the amplitude and phase of a sample, at a resolution that significantly exceeds the cutoff frequency of the microscope objective lens. At the same time, FPM algorithm is able to leverage on the redundancy within the set of acquired FPM bright-field images to estimate the microscope aberrations, which usually deteriorate in regions further away from the FOV's center. Second, the procedure acquires a raw wide-FOV fluorescence image within the same setup. Lack of moving parts allows us to use the FPM-estimated aberration map to computationally correct for the aberrations in the fluorescence image through deconvolution. Overlaying the aberration-corrected fluorescence image on top of the high-resolution bright-field image can be done with accurate spatial correspondence. This can provide means to identifying fluorescent regions of interest within the context of the sample's bright-field information. An experimental demonstration successfully improves the bright-field resolution of fixed, stained and fluorescently tagged HeLa cells by a factor of 4.9, and reduces the error caused by aberrations in a fluorescence image by 31%, over a field of view of 6.2 mm by 9.3 mm. For optimal deconvolution, we show the fluorescence image needs to have a signal-to-noise ratio of ~18.

  8. Derivative Form of Off-axis Aberration Correction Surface and Its Application in Solar Energy Concentration

    Institute of Scientific and Technical Information of China (English)

    LI Li; CHEN Ying-Tian; HU Sen

    2009-01-01

    By using the derivative method, we obtained the same result with that of the previous work of Chen et al.in 2006.Different from the integral form, the derivative form of the surface expression published in this paper is derived from differential equation and based on the theory of non-imaging focusing heliostat proposed by Chen et al.in 2001.The comparison of the derivative form of fixed aberration correction surface has been made with that of integral form surface as well as that of spherical surface in concentrating the solar ray.

  9. Dynamic Aberration Correction for Conformal Window of High-Speed Aircraft Using Optimized Model-Based Wavefront Sensorless Adaptive Optics

    Science.gov (United States)

    Dong, Bing; Li, Yan; Han, Xin-li; Hu, Bin

    2016-01-01

    For high-speed aircraft, a conformal window is used to optimize the aerodynamic performance. However, the local shape of the conformal window leads to large amounts of dynamic aberrations varying with look angle. In this paper, deformable mirror (DM) and model-based wavefront sensorless adaptive optics (WSLAO) are used for dynamic aberration correction of an infrared remote sensor equipped with a conformal window and scanning mirror. In model-based WSLAO, aberration is captured using Lukosz mode, and we use the low spatial frequency content of the image spectral density as the metric function. Simulations show that aberrations induced by the conformal window are dominated by some low-order Lukosz modes. To optimize the dynamic correction, we can only correct dominant Lukosz modes and the image size can be minimized to reduce the time required to compute the metric function. In our experiment, a 37-channel DM is used to mimic the dynamic aberration of conformal window with scanning rate of 10 degrees per second. A 52-channel DM is used for correction. For a 128 × 128 image, the mean value of image sharpness during dynamic correction is 1.436 × 10−5 in optimized correction and is 1.427 × 10−5 in un-optimized correction. We also demonstrated that model-based WSLAO can achieve convergence two times faster than traditional stochastic parallel gradient descent (SPGD) method. PMID:27598161

  10. Dynamic Aberration Correction for Conformal Window of High-Speed Aircraft Using Optimized Model-Based Wavefront Sensorless Adaptive Optics.

    Science.gov (United States)

    Dong, Bing; Li, Yan; Han, Xin-Li; Hu, Bin

    2016-09-02

    For high-speed aircraft, a conformal window is used to optimize the aerodynamic performance. However, the local shape of the conformal window leads to large amounts of dynamic aberrations varying with look angle. In this paper, deformable mirror (DM) and model-based wavefront sensorless adaptive optics (WSLAO) are used for dynamic aberration correction of an infrared remote sensor equipped with a conformal window and scanning mirror. In model-based WSLAO, aberration is captured using Lukosz mode, and we use the low spatial frequency content of the image spectral density as the metric function. Simulations show that aberrations induced by the conformal window are dominated by some low-order Lukosz modes. To optimize the dynamic correction, we can only correct dominant Lukosz modes and the image size can be minimized to reduce the time required to compute the metric function. In our experiment, a 37-channel DM is used to mimic the dynamic aberration of conformal window with scanning rate of 10 degrees per second. A 52-channel DM is used for correction. For a 128 × 128 image, the mean value of image sharpness during dynamic correction is 1.436 × 10(-5) in optimized correction and is 1.427 × 10(-5) in un-optimized correction. We also demonstrated that model-based WSLAO can achieve convergence two times faster than traditional stochastic parallel gradient descent (SPGD) method.

  11. Optimum aberration coefficients for recording high-resolution off-axis holograms in a Cs-corrected TEM

    Energy Technology Data Exchange (ETDEWEB)

    Linck, Martin, E-mail: linck@ceos-gmbh.de [CEOS GmbH, Englerstr. 28, D-69126 Heidelberg (Germany)

    2013-01-15

    Amongst the impressive improvements in high-resolution electron microscopy, the Cs-corrector also has significantly enhanced the capabilities of off-axis electron holography. Recently, it has been shown that the signal above noise in the reconstructable phase can be significantly improved by combining holography and hardware aberration correction. Additionally, with a spherical aberration close to zero, the traditional optimum focus for recording high-resolution holograms ('Lichte's defocus') has become less stringent and both, defocus and spherical aberration, can be selected freely within a certain range. This new degree of freedom can be used to improve the signal resolution in the holographically reconstructed object wave locally, e.g. at the atomic positions. A brute force simulation study for an aberration corrected 200 kV TEM is performed to determine optimum values for defocus and spherical aberration for best possible signal to noise in the reconstructed atomic phase signals. Compared to the optimum aberrations for conventional phase contrast imaging (NCSI), which produce 'bright atoms' in the image intensity, the resulting optimum values of defocus and spherical aberration for off-axis holography enable 'black atom contrast' in the hologram. However, they can significantly enhance the local signal resolution at the atomic positions. At the same time, the benefits of hardware aberration correction for high-resolution off-axis holography are preserved. It turns out that the optimum is depending on the object and its thickness and therefore not universal. -- Highlights: Black-Right-Pointing-Pointer Optimized aberration parameters for high-resolution off-axis holography. Black-Right-Pointing-Pointer Simulation and analysis of noise in high-resolution off-axis holograms. Black-Right-Pointing-Pointer Improving signal resolution in the holographically reconstructed phase shift. Black-Right-Pointing-Pointer Comparison of &apos

  12. Phase aberration correction by multi-stencils fast marching method using sound speed image in ultrasound computed tomography

    Science.gov (United States)

    Qu, Xiaolei; Azuma, Takashi; Lin, Hongxiang; Imoto, Haruka; Tamano, Satoshi; Takagi, Shu; Umemura, Shin-Ichiro; Sakuma, Ichiro; Matsumoto, Yoichiro

    2016-04-01

    Reflection image from ultrasound computed tomography (USCT) system can be obtained by synthetic aperture technique, however its quality is decreased by phase aberration caused by inhomogeneous media. Therefore, phase aberration correction is important to improve image quality. In this study, multi-stencils fast marching method (MSFMM) is employed for phase correction. The MSFMM is an accurate and fast solution of Eikonal equation which considers the refraction. The proposed method includes two steps. First, the MSFMM is used to compute sound propagation time from each element to each image gird point using sound speed image of USCT. Second, synthetic aperture technique is employed to obtain reflection image using the computed propagation time. To evaluate the proposed method, both numerical simulation and phantom experiment were conducted. With regard to numerical simulation, both quantitative and qualitative comparisons between reflection images with and without phase aberration correction were given. In the quantitative comparison, the diameters of point spread function (PSF) in reflection images of a two layer structure were presented. In the qualitative comparison, reflection images of simple circle and complex breast modes with phase aberration correction show higher quality than that without the correction. In respect to phantom experiment, a piece of breast phantom with artificial glandular structure inside was scanned by a USCT prototype, and the artificial glandular structure is able to be visible more clearly in the reflection image with phase aberration correction than in that without the correction. In this study, a phase aberration correction method by the MSFMM are proposed for reflection image of the USCT.

  13. Dark-field electron holography for the mapping of strain in nanostructures: correcting artefacts and aberrations

    International Nuclear Information System (INIS)

    We present details of the new electron holographic dark-field technique (HoloDark) for mapping strain in nanostructures. A diffracted beam emanating from an unstrained region of crystal is interfered (with the aid of an electrostatic biprism) with a diffracted beam from the strained region of interest. Geometric phase analysis (GPA) of the holographic fringes determines the relative deformation of the two crystalline lattices. Strain can be measured to high precision, with nanometre spatial resolution and for micron fields of view. Experiments are carried out on the SACTEM-Toulouse, a Tecnai F20 (FEI) equipped with imaging aberration corrector (CEOS), field-emission gun and rotatable biprism (FEI). We operate the microscope in free-lens control with the main objective lens switched off and using the corrector transfer lenses as a Lorentz lens. We will present measurements of strain in test nanostructures and show how artefacts from thickness variations can be removed. Finally, we show our first results using a recently developed aberration-corrected Lorentz mode (CEOS).

  14. Prospects for versatile phase manipulation in the TEM: Beyond aberration correction

    Energy Technology Data Exchange (ETDEWEB)

    Guzzinati, Giulio; Clark, Laura; Béché, Armand; Juchtmans, Roeland; Van Boxem, Ruben [EMAT, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp (Belgium); Mazilu, Michael [SUPA, School of Physics and Astronomy, University of St Andrews, St Andrews KY16 9SS (United Kingdom); Verbeeck, Jo, E-mail: jo.verbeeck@uantwerpen.be [EMAT, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp (Belgium)

    2015-04-15

    In this paper we explore the desirability of a transmission electron microscope in which the phase of the electron wave can be freely controlled. We discuss different existing methods to manipulate the phase of the electron wave and their limitations. We show how with the help of current techniques the electron wave can already be crafted into specific classes of waves each having their own peculiar properties. Assuming a versatile phase modulation device is feasible, we explore possible benefits and methods that could come into existence borrowing from light optics where the so-called spatial light modulators provide programmable phase plates for quite some time now. We demonstrate that a fully controllable phase plate building on Harald Rose's legacy in aberration correction and electron optics in general would open an exciting field of research and applications. - Highlights: • We offer a review of available phase manipulation techniques. • We demonstrate a method for producing Airy waves through aberration manipulation. • We outline hypothetical applications of arbitrary phase manipulation methods.

  15. Dark-field electron holography for the mapping of strain in nanostructures: correcting artefacts and aberrations

    Energy Technology Data Exchange (ETDEWEB)

    Hytch, M J; Houdellier, F; Snoeck, E; Huee, F, E-mail: hytch@cemes.f [CEMES-CNRS, 29 rue Jeanne Marvig, 31055 Toulouse (France)

    2010-07-01

    We present details of the new electron holographic dark-field technique (HoloDark) for mapping strain in nanostructures. A diffracted beam emanating from an unstrained region of crystal is interfered (with the aid of an electrostatic biprism) with a diffracted beam from the strained region of interest. Geometric phase analysis (GPA) of the holographic fringes determines the relative deformation of the two crystalline lattices. Strain can be measured to high precision, with nanometre spatial resolution and for micron fields of view. Experiments are carried out on the SACTEM-Toulouse, a Tecnai F20 (FEI) equipped with imaging aberration corrector (CEOS), field-emission gun and rotatable biprism (FEI). We operate the microscope in free-lens control with the main objective lens switched off and using the corrector transfer lenses as a Lorentz lens. We will present measurements of strain in test nanostructures and show how artefacts from thickness variations can be removed. Finally, we show our first results using a recently developed aberration-corrected Lorentz mode (CEOS).

  16. Bright-field imaging of compound semiconductors using aberration-corrected scanning transmission electron microscopy

    Science.gov (United States)

    Aoki, Toshihiro; Lu, Jing; McCartney, Martha R.; Smith, David J.

    2016-09-01

    This study reports the observation of six different zincblende compound semiconductors in [110] projection using large-collection-angle bright-field (LABF) imaging with an aberration-corrected scanning transmission electron microscope. Phase contrast is completely suppressed when the collection semi-angle is set equal to the convergence semi-angle and there are no reversals in image contrast with changes in defocus or thickness. The optimum focus for imaging closely separated pairs of atomic columns (‘dumbbells’) is unique and easily recognized, and the positions of atomic columns occupied by heavier atoms always have darker intensity than those occupied by lighter atoms. Thus, the crystal polarity of compound semiconductors can be determined unambiguously. Moreover, it is concluded that the LABF imaging mode will be highly beneficial for studying other more complicated heterostructures at the atomic scale.

  17. Optimization and stability of the contrast transfer function in aberration-corrected electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Tromp, R.M., E-mail: rtromp@us.ibm.com [IBM T.J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY 10598 (United States); Leiden Institute of Physics, Kamerlingh Onnes Laboratory, Niels Bohrweg 2, 2333 CA Leiden (Netherlands); Schramm, S.M. [Leiden Institute of Physics, Kamerlingh Onnes Laboratory, Niels Bohrweg 2, 2333 CA Leiden (Netherlands)

    2013-02-15

    The Contrast Transfer Function (CTF) describes the manner in which the electron microscope modifies the object exit wave function as a result of objective lens aberrations. For optimum resolution in C{sub 3}-corrected microscopes it is well established that a small negative value of C{sub 3}, offset by positive values of C{sub 5} and defocus C{sub 1} results in the most optimal instrument resolution, and optimization of the CTF has been the subject of several studies. Here we describe a simple design procedure for the CTF that results in a most even transfer of information below the resolution limit. We address not only the resolution of the instrument, but also the stability of the CTF in the presence of small disturbances in C{sub 1} and C{sub 3}. We show that resolution can be traded for stability in a rational and transparent fashion. These topics are discussed quantitatively for both weak-phase and strong-phase (or amplitude) objects. The results apply equally to instruments at high electron energy (TEM) and at very low electron energy (LEEM), as the basic optical properties of the imaging lenses are essentially identical. - Highlights: ► An optimized Contrast Transfer Function for aberration corrected electron microscopes is proposed. ► Based on the properties of the CTF near optimum settings, we address its stability. ► Over some range of parameters resolution can be traded for stability. ► These issues are addressed for weak-phase objects, as well as strong-phase and amplitude object. ► We compare our results with CTF settings previously proposed.

  18. Optimization and stability of the contrast transfer function in aberration-corrected electron microscopy

    International Nuclear Information System (INIS)

    The Contrast Transfer Function (CTF) describes the manner in which the electron microscope modifies the object exit wave function as a result of objective lens aberrations. For optimum resolution in C3-corrected microscopes it is well established that a small negative value of C3, offset by positive values of C5 and defocus C1 results in the most optimal instrument resolution, and optimization of the CTF has been the subject of several studies. Here we describe a simple design procedure for the CTF that results in a most even transfer of information below the resolution limit. We address not only the resolution of the instrument, but also the stability of the CTF in the presence of small disturbances in C1 and C3. We show that resolution can be traded for stability in a rational and transparent fashion. These topics are discussed quantitatively for both weak-phase and strong-phase (or amplitude) objects. The results apply equally to instruments at high electron energy (TEM) and at very low electron energy (LEEM), as the basic optical properties of the imaging lenses are essentially identical. - Highlights: ► An optimized Contrast Transfer Function for aberration corrected electron microscopes is proposed. ► Based on the properties of the CTF near optimum settings, we address its stability. ► Over some range of parameters resolution can be traded for stability. ► These issues are addressed for weak-phase objects, as well as strong-phase and amplitude object. ► We compare our results with CTF settings previously proposed

  19. TOPICAL REVIEW: Present status and future prospects of spherical aberration corrected TEM/STEM for study of nanomaterials

    Directory of Open Access Journals (Sweden)

    Nobuo Tanaka

    2008-01-01

    Full Text Available The present status of Cs-corrected TEM/STEM is described from the viewpoint of the observation of nanomaterials. Characteristic features in TEM and STEM are explained using the experimental data obtained by our group and other research groups. Cs correction up to the 3rd-order aberration of an objective lens has already been established and research interest is focused on correcting the 5th-order spherical aberration and the chromatic aberration in combination with the development of a monochromator below an electron gun for smaller point-to-point resolution in optics. Another fundamental area of interest is the limitation of TEM and STEM resolution from the viewpoint of the scattering of electrons in crystals. The minimum size of the exit-wave function below samples undergoing TEM imaging is determined from the calculation of scattering around related atomic columns in the crystals. STEM does not have this limitation because the resolution is, in principle, determined by the probe size. One of the future prospects of Cs-corrected TEM/STEM is the possibility of extending the space around the sample holder by correcting the chromatic and spherical aberrations. This wider space will contribute to the ease of performing in situ experiments and various combinations of TEM and other analysis methods. High-resolution, in situ dynamic and 3D observations/analysis are the most important keywords in the next decade of high-resolution electron microscopy.

  20. The first observation of titanate nanotubes by spherical aberration corrected high-resolution transmission electron microscopy

    Science.gov (United States)

    Miao, L.; Tanemura, S.; Jiang, T.; Tanemura, M.; Yoshida, K.; Tanaka, N.; Xu, G.

    2009-07-01

    Multi-wall titanate nanotubes (MW-TNNTs) with high aspect ratio, large surface area and good uniformity were produced by alkaline hydrothermal treatment of grounded TiO 2 aerogels and further by applying freeze-drying. Not only the crystal phase and diameter, but also morphology of the starting materials impact on the aspect ratio and transformation efficiency of the obtained nanotubes. Other parameters, such as pH value during neutralization process and drying method for the final products, are important to control length and dispersion of MW-TNNTs. By spherical aberration corrected high-resolution transmission-electron-microscopy (Cs-corrected HRTEM) with lateral space resolution of 0.14 nm at 200 kV accelerating voltage and electron energy loss spectrum (EELS), the detailed structural analysis of MW-TNNTs reveals that (1) diameters of inner and outer tubes are about 4-7 nm and 10 nm, respectively, (2) numbers of layers are different from part to part along the longitudinal tube axis, (3) the walls of the tubes have interlayer spacing of 0.70-0.80 nm and the lateral fringes which are vertical to the walls have spacing of 0.32 nm, (4) each layer of MW-TNNT is the nanosheet composed by the arrayed TiO 6 octahedrons, and respective octahedron being slightly strained, and (5) no chirality of MW-TNNT tubular structure is observed.

  1. First experimental proof for aberration correction in XPEEM: Resolution, transmission enhancement, and limitation by space charge effects

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Th., E-mail: schmidtt@fhi-berlin.mpg.de [Fritz Haber Institute of the Max Planck Society, Department of Chemical Physics, Faradayweg 4-6, D-14195 Berlin (Germany); Sala, A.; Marchetto, H. [Fritz Haber Institute of the Max Planck Society, Department of Chemical Physics, Faradayweg 4-6, D-14195 Berlin (Germany); Umbach, E. [Karlsruhe Institute of Technology, 76021 Karlsruhe (Germany); Freund, H.-J. [Fritz Haber Institute of the Max Planck Society, Department of Chemical Physics, Faradayweg 4-6, D-14195 Berlin (Germany)

    2013-03-15

    The positive effect of double aberration correction in x-ray induced Photoelectron Emission Microscopy (XPEEM) has been successfully demonstrated for both, the lateral resolution and the transmission, using the Au 4f XPS peak for element specific imaging at a kinetic energy of 113 eV. The lateral resolution is improved by a factor of four, compared to a non-corrected system, whereas the transmission is enhanced by a factor of 5 at a moderate resolution of 80 nm. With an optimized system setting, a lateral resolution of 18 nm could be achieved, which is up to now the best value reported for energy filtered XPEEM imaging. However, the absolute resolution does not yet reach the theoretical limit of 2 nm, which is due to space charge limitation. This occurs along the entire optical axis up to the contrast aperture. In XPEEM the pulsed time structure of the exciting soft x-ray light source causes a short and highly intense electron pulse, which results in an image blurring. In contrast, the imaging with elastically reflected electrons in the low energy electron microscopy (LEEM) mode yields a resolution clearly below 5 nm. Technical solutions to reduce the space charge effect in an aberration-corrected spectro-microscope are discussed. - Highlights: ► First successful double aberration correction in XPEEM. ► Improvement of resolution and transmission by aberration correction. ► Lateral resolution of 18 nm in energy filtered XPEEM is the best up to now reported value. ► First investigation of space charge effects in aberrations corrected PEEM.

  2. Aberration-corrected electron microscopy of MnAs and As nanocrystals and voids in annealed (Ga,Mn)As

    DEFF Research Database (Denmark)

    Kovács, András; Kasama, Takeshi; Sadowski, J.;

    2011-01-01

    Aberration-corrected transmission electron microscopy is used to study voids and nano-crystalline MnAs and As phases formed during the annealing of Mn-doped GaAs. The effects of defocus and inner annular dark-field detector semi-angle on contrast of the nanocrystals are discussed....

  3. Aspherical Lens Design Using Genetic Algorithm for Reducing Aberrations in Multifocal Artificial Intraocular Lens

    Directory of Open Access Journals (Sweden)

    Chih-Ta Yen

    2015-09-01

    Full Text Available A complex intraocular lens (IOL design involving numerous uncertain variables is proposed. We integrated a genetic algorithm (GA with the commercial optical design software of (CODE V to design a multifocal IOL for the human eye. We mainly used an aspherical lens in the initial state to the crystalline type; therefore, we used the internal human eye model in the software. The proposed optimized algorithm employs a GA method for optimally simulating the focusing function of the human eye; in this method, the thickness and curvature of the anterior lens and the posterior part of the IOL were varied. A comparison of the proposed GA-designed IOLs and those designed using a CODE V built-in optimal algorithm for 550 degrees myopia and 175 degrees astigmatism conditions of the human eye for pupil size 6 mm showed that the proposed IOL design improved the spot size of root mean square (RMS, tangential coma (TCO and modulation transfer function (MTF at a spatial frequency of 30 with a pupil size of 6 mm by approximately 17%, 43% and 35%, respectively. However, the worst performance of spherical aberration (SA was lower than 46%, because the optical design involves a tradeoff between all aberrations. Compared with the traditional CODE V built-in optimal scheme, the proposed IOL design can efficiently improve the critical parameters, namely TCO, RMS, and MTF.

  4. Correction of cell-induced optical aberrations in a fluorescence fluctuation microscope.

    OpenAIRE

    Leroux, Charles-Edouard; Grichine, Alexei; Wang, Irène; Delon, Antoine

    2013-01-01

    International audience We describe the effect of optical aberrations on fluorescence fluctuations microscopy (FFM), when focusing through a single living cell. FFM measurements are performed in an aqueous fluorescent solution and prove to be a highly sensitive tool to assess the optical aberrations introduced by the cell. We demonstrate an adaptive optics (AO) system to remove the aberration-related bias in the FFM measurements. Our data show that AO is not only useful when imaging deep in...

  5. Double aberration-corrected TEM/STEM of tungstated zirconia nanocatalysts for the synthesis of paracetamol

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, K; Boyes, E D; Gai, P L [York JEOL Nanocentre (United Kingdom); Shiju, N R; Brown, D R, E-mail: pgb500@york.ac.u [Department of Chemical and Biological Sciences, University of Huddersfield, Huddersfield, HD1 3DH (United Kingdom)

    2010-07-01

    We report highly active tungstated zirconia nanocatalysts for the synthesis of paracetamol by Beckmann rearrangement of 4-hydroxyacetophenone oxime. Double aberration-corrected (2AC)-TEM/STEM studies were performed in a JEOL 2200FS FEG TEM/STEM at the 1 Angstrom (1 A = 0.1 nanometer) level. Observations at close to zero defocus were carried out using the AC-TEM as well as AC-STEM including high angle annular dark field (HAADF) imaging, from the same areas of the catalyst crystallites. The studies from the same areas have revealed the location and the nanostructure of the polytungstate species (clusters) and the nanograins of zirconia. The AC (S)TEM was crucial to observe the nanostructure and location of polytungstate clusters on the zirconia grains. Polytungstate clusters as small as 0.5 nm have been identified using the HAADF-STEM. The nanostructures of the catalyst and the W surface density have been correlated with paracetamol reaction studies. The results demonstrate the nature of active sites and high activity of the tungstated zirconia nanocatalyst, which is an environmentally clean alternative to the current homogeneous process.

  6. Molecular Docking and Aberration-Corrected STEM of Palladium Nanoparticles on Viral Templates

    Directory of Open Access Journals (Sweden)

    Liliana Carreño-Fuentes

    2016-08-01

    Full Text Available Viral templates are highly versatile biotemplates used for the synthesis of nanostructured materials. Rotavirus VP6 self-assembles into nanotubular hollow structures with well-defined diameters and variable lengths, serving as a nucleic acid-free biotemplate to synthesize metal nanoparticles of controlled size, shape, and orientation. Molecular docking simulations show that exposed residues (H173-S240-D242 and N200-N310 of VP6 have the ability to specifically bind Pd(II ions, which serve as nucleation sites for the growth and stabilization of palladium nanoclusters. Using VP6 nanotubes as biotemplates allows for obtaining small Pd particles of 1–5 nm in diameter. Advanced electron microscopy imaging and characterization through ultra-high-resolution field-emission scanning electron microscopy (UHR-FE-SEM and spherical aberration-corrected scanning transmission electron microscopy (Cs-STEM at a low voltage dose (80 kV reveals, with high spatial resolution, the structure of Pd nanoparticles attached to the macromolecular biotemplates.

  7. Chromosome therapy. Correction of large chromosomal aberrations by inducing ring chromosomes in induced pluripotent stem cells (iPSCs).

    Science.gov (United States)

    Kim, Taehyun; Bershteyn, Marina; Wynshaw-Boris, Anthony

    2014-01-01

    The fusion of the short (p) and long (q) arms of a chromosome is referred to as a "ring chromosome." Ring chromosome disorders occur in approximately 1 in 50,000-100,000 patients. Ring chromosomes can result in birth defects, mental disabilities, and growth retardation if additional genes are deleted during the formation of the ring. Due to the severity of these large-scale aberrations affecting multiple contiguous genes, no possible therapeutic strategies for ring chromosome disorders have so far been proposed. Our recent study (Bershteyn et al.) using patient-derived fibroblast lines containing ring chromosomes, found that cellular reprogramming of these fibroblasts into induced pluripotent stem cells (iPSCs) resulted in the cell-autonomous correction of the ring chromosomal aberration via compensatory uniparental disomy (UPD). These observations have important implications for studying the mechanism of chromosomal number control and may lead to the development of effective therapies for other, more common, chromosomal aberrations.

  8. Beam hardening correction algorithm in microtomography images

    Energy Technology Data Exchange (ETDEWEB)

    Sales, Erika S.; Lima, Inaya C.B.; Lopes, Ricardo T., E-mail: esales@con.ufrj.b, E-mail: ricardo@lin.ufrj.b [Coordenacao dos Programas de Pos-graduacao de Engenharia (COPPE/UFRJ), Rio de Janeiro, RJ (Brazil). Lab. de Instrumentacao Nuclear; Assis, Joaquim T. de, E-mail: joaquim@iprj.uerj.b [Universidade do Estado do Rio de Janeiro (UERJ), Nova Friburgo, RJ (Brazil). Inst. Politecnico. Dept. de Engenharia Mecanica

    2009-07-01

    Quantification of mineral density of bone samples is directly related to the attenuation coefficient of bone. The X-rays used in microtomography images are polychromatic and have a moderately broad spectrum of energy, which makes the low-energy X-rays passing through a sample to be absorbed, causing a decrease in the attenuation coefficient and possibly artifacts. This decrease in the attenuation coefficient is due to a process called beam hardening. In this work the beam hardening of microtomography images of vertebrae of Wistar rats subjected to a study of hyperthyroidism was corrected by the method of linearization of the projections. It was discretized using a spectrum in energy, also called the spectrum of Herman. The results without correction for beam hardening showed significant differences in bone volume, which could lead to a possible diagnosis of osteoporosis. But the data with correction showed a decrease in bone volume, but this decrease was not significant in a confidence interval of 95%. (author)

  9. A NOVEL ADAPTIVE ALGORITHM OF CPE CORRECTION FOR OFDM SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    Cai Zejian; Ge Jianhua; Wu Guohang

    2005-01-01

    On the basis of the analysis of the effect of PHase Noise (PHN) and Common Phase Error (CPE) on Orthogonal Frequency Division Multiplexing (OFDM) systems, a cost function is constructed. By the cost function and the idea of Least-Mean-Square (LMS) adaptive algorithm, the adaptive algorithm for the correction of CPE is presented. The simulations have been performed to investigate the performance for tracking PHN and estimating CPE, the results show that the algorithm performs soundly.

  10. Optical study on the vision correction and supernormal vision based on the wave-front aberrations of human eye

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In this paper we present the recent research results in the field of vision correction and supernormal vision according to the actual measurements of the wave-front aberrations and the corneal surface topography,the clinical detection of the visual function and the laser corneal refractive surgery,and the optimization of the optical system. These include the features of the aberrations of human eye with different pupil sizes,different fields of view and temporal accommodation,the influence of the polychromatic illumination of the visible wavelength on the supernormal vision,and the effect of the existing laser corneal refractive surgery on the wave-front ab-errations of the eye. It is shown that the wave-front aberration of human eye is of temporal variation and of synthesis with multi impact factors. To achieve super-normal vision,an optimum engineering data for the customized laser corneal sur-gery should be firstly acquired,which may involve the dynamic free-form optical surface. Although the myopia can be corrected by the laser in situ keratomileusis(LASIK) in a certain degree,it brings about negative effects under scotopic condi-tions.

  11. Optical study on the vision correction and supernormal vision based on the wave-front aberrations of human eye

    Institute of Scientific and Technical Information of China (English)

    MU GuoGuang; WANG ZhaoQi; LIU YongJi; QUAN Wei; WANG Yang; WANG Wei

    2007-01-01

    In this paper we present the recent research results in the field of vision correction and supernormal vision according to the actual measurements of the wave-front aberrations and the corneal surface topography, the clinical detection of the visual function and the laser corneal refractive surgery, and the optimization of the optical system. These include the features of the aberrations of human eye with different pupil sizes, different fields of view and temporal accommodation, the influence of the polychromatic illumination of the visible wavelength on the supernormal vision,and the effect of the existing laser corneal refractive surgery on the wave-front aberrations of the eye. It is shown that the wave-front aberration of human eye is of temporal variation and of synthesis with multi impact factors. To achieve supernormal vision, an optimum engineering data for the customized laser corneal surgery should be firstly acquired, which may involve the dynamic free-form optical surface. Although the myopia can be corrected by the laser in situ keratomileusis (LASlK) in a certain degree, it brings about negative effects under scotopic conditions.

  12. Genetic algorithm for chromaticity correction in diffraction limited storage rings

    Science.gov (United States)

    Ehrlichman, M. P.

    2016-04-01

    A multiobjective genetic algorithm is developed for optimizing nonlinearities in diffraction limited storage rings. This algorithm determines sextupole and octupole strengths for chromaticity correction that deliver optimized dynamic aperture and beam lifetime. The algorithm makes use of dominance constraints to breed desirable properties into the early generations. The momentum aperture is optimized indirectly by constraining the chromatic tune footprint and optimizing the off-energy dynamic aperture. The result is an effective and computationally efficient technique for correcting chromaticity in a storage ring while maintaining optimal dynamic aperture and beam lifetime.

  13. Adaptive bad pixel correction algorithm for IRFPA based on PCNN

    Science.gov (United States)

    Leng, Hanbing; Zhou, Zuofeng; Cao, Jianzhong; Yi, Bo; Yan, Aqi; Zhang, Jian

    2013-10-01

    Bad pixels and response non-uniformity are the primary obstacles when IRFPA is used in different thermal imaging systems. The bad pixels of IRFPA include fixed bad pixels and random bad pixels. The former is caused by material or manufacture defect and their positions are always fixed, the latter is caused by temperature drift and their positions are always changing. Traditional radiometric calibration-based bad pixel detection and compensation algorithm is only valid to the fixed bad pixels. Scene-based bad pixel correction algorithm is the effective way to eliminate these two kinds of bad pixels. Currently, the most used scene-based bad pixel correction algorithm is based on adaptive median filter (AMF). In this algorithm, bad pixels are regarded as image noise and then be replaced by filtered value. However, missed correction and false correction often happens when AMF is used to handle complex infrared scenes. To solve this problem, a new adaptive bad pixel correction algorithm based on pulse coupled neural networks (PCNN) is proposed. Potential bad pixels are detected by PCNN in the first step, then image sequences are used periodically to confirm the real bad pixels and exclude the false one, finally bad pixels are replaced by the filtered result. With the real infrared images obtained from a camera, the experiment results show the effectiveness of the proposed algorithm.

  14. Correction of cell-induced optical aberrations in a fluorescence fluctuation microscope

    CERN Document Server

    Leroux, Charles-Edouard; Wang, Irène; Delon, Antoine

    2014-01-01

    We describe the effect of optical aberrations on fluorescence fluctuations microscopy (FFM), when focusing through a single living cell. FFM measurements are performed in an aqueous fluorescent solution and prove to be a highly sensitive tool to assess the optical aberrations introduced by the cell. We demonstrate an adaptive optics (AO) system to remove the aberration-related bias in the FFM measurements. Our data show that AO is not only useful when imaging deep in tissues but also when performing FFM measurements through a single cellular layer. This work paves the way for the application of FFM to complex three-dimensional multicellular samples.

  15. Aberration corrected and monochromated environmental transmission electron microscopy: challenges and prospects for materials science

    DEFF Research Database (Denmark)

    Hansen, Thomas Willum; Wagner, Jakob Birkedal; Dunin-Borkowski, Rafal E.

    2010-01-01

    The latest generation of environmental transmission electron microscopes incorporates aberration correctors and monochromators, allowing studies of chemical reactions and growth processes with improved spatial resolution and spectral sensitivity. Here, we describe the performance of such an instr......The latest generation of environmental transmission electron microscopes incorporates aberration correctors and monochromators, allowing studies of chemical reactions and growth processes with improved spatial resolution and spectral sensitivity. Here, we describe the performance...

  16. A burst-correcting algorithm for Reed Solomon codes

    Science.gov (United States)

    Chen, J.; Owsley, P.

    1990-01-01

    The Bose, Chaudhuri, and Hocquenghem (BCH) codes form a large class of powerful error-correcting cyclic codes. Among the non-binary BCH codes, the most important subclass is the Reed Solomon (RS) codes. Reed Solomon codes have the ability to correct random and burst errors. It is well known that an (n,k) RS code can correct up to (n-k)/2 random errors. When burst errors are involved, the error correcting ability of the RS code can be increased beyond (n-k)/2. It has previously been show that RS codes can reliably correct burst errors of length greater than (n-k)/2. In this paper, a new decoding algorithm is given which can also correct a burst error of length greater than (n-k)/2.

  17. Detection of Aberrant Data Points for an effective Effort Estimation using an Enhanced Algorithm with Adaptive Features

    Directory of Open Access Journals (Sweden)

    S. Sridhar

    2012-01-01

    Full Text Available Problem statement: The spiraling growth of IT industry has witnessed an unprecedented change in the software development paradigm, from algorithmic models to machine learning techniques. At present, there are no standard methods to predict the accuracy of software cost estimation, which is an important goal of the software community. Approach: This study proposes a simple and systematic algorithmic procedure for analogy based software cost prediction to detect the aberrant data points. The algorithm is analyzed and correlated with the Desharnais and NASA datasets containing all adaptive features with numerical and categorical variables. Results: The interpreted curves using the above datasets depict a discernible anomaly for the dataset having more categorical variables, thereby indicating the erroneous data points. Conclusion: The elimination of aberrant data points using the new algorithmic method improves the accuracy of software cost estimation using historical data sets.

  18. Spherical Aberration Correction Using Refractive-Diffractive Lenses with an Analytic-Numerical Method

    Directory of Open Access Journals (Sweden)

    Sergio Vázquez-Montiel

    2010-01-01

    Full Text Available We propose an alternative method to design diffractive lenses free of spherical aberration for monochromatic light. Our method allows us to design diffractive lenses with the diffraction structure recorded on the last surface; this surface can be flat or curved with rotation symmetry. The equations that we propose calculate the diffraction profiles for any substratum, for any f-number, and for any position of the object. We use the lens phase coefficients to compensate the spherical aberration. To calculate these coefficients, we use an analytic-numerical method. The calculations are exact, and the optimization process is not required.

  19. Comparison of analytical and numerical approaches for CT-based aberration correction in transcranial passive acoustic imaging

    Science.gov (United States)

    Jones, Ryan M.; Hynynen, Kullervo

    2016-01-01

    Computed tomography (CT)-based aberration corrections are employed in transcranial ultrasound both for therapy and imaging. In this study, analytical and numerical approaches for calculating aberration corrections based on CT data were compared, with a particular focus on their application to transcranial passive imaging. Two models were investigated: a three-dimensional full-wave numerical model (Connor and Hynynen 2004 IEEE Trans. Biomed. Eng. 51 1693-706) based on the Westervelt equation, and an analytical method (Clement and Hynynen 2002 Ultrasound Med. Biol. 28 617-24) similar to that currently employed by commercial brain therapy systems. Trans-skull time delay corrections calculated from each model were applied to data acquired by a sparse hemispherical (30 cm diameter) receiver array (128 piezoceramic discs: 2.5 mm diameter, 612 kHz center frequency) passively listening through ex vivo human skullcaps (n  =  4) to emissions from a narrow-band, fixed source emitter (1 mm diameter, 516 kHz center frequency). Measurements were taken at various locations within the cranial cavity by moving the source around the field using a three-axis positioning system. Images generated through passive beamforming using CT-based skull corrections were compared with those obtained through an invasive source-based approach, as well as images formed without skull corrections, using the main lobe volume, positional shift, peak sidelobe ratio, and image signal-to-noise ratio as metrics for image quality. For each CT-based model, corrections achieved by allowing for heterogeneous skull acoustical parameters in simulation outperformed the corresponding case where homogeneous parameters were assumed. Of the CT-based methods investigated, the full-wave model provided the best imaging results at the cost of computational complexity. These results highlight the importance of accurately modeling trans-skull propagation when calculating CT-based aberration corrections

  20. Algorithmic scatter correction in dual-energy digital mammography

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Xi; Mou, Xuanqin [Institute of Image Processing and Pattern Recognition, Xi' an Jiaotong University, Xi' an, Shaanxi 710049 (China); Nishikawa, Robert M.; Lau, Beverly A. [Department of Radiology, The University of Chicago, Chicago, Illinois 60637 (United States); Chan, Suk-tak [Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom (Hong Kong); Zhang, Lei [Department of Computing, The Hong Kong Polytechnic University, Hung Hom (Hong Kong)

    2013-11-15

    Purpose: Small calcifications are often the earliest and the main indicator of breast cancer. Dual-energy digital mammography (DEDM) has been considered as a promising technique to improve the detectability of calcifications since it can be used to suppress the contrast between adipose and glandular tissues of the breast. X-ray scatter leads to erroneous calculations of the DEDM image. Although the pinhole-array interpolation method can estimate scattered radiations, it requires extra exposures to measure the scatter and apply the correction. The purpose of this work is to design an algorithmic method for scatter correction in DEDM without extra exposures.Methods: In this paper, a scatter correction method for DEDM was developed based on the knowledge that scattered radiation has small spatial variation and that the majority of pixels in a mammogram are noncalcification pixels. The scatter fraction was estimated in the DEDM calculation and the measured scatter fraction was used to remove scatter from the image. The scatter correction method was implemented on a commercial full-field digital mammography system with breast tissue equivalent phantom and calcification phantom. The authors also implemented the pinhole-array interpolation scatter correction method on the system. Phantom results for both methods are presented and discussed. The authors compared the background DE calcification signals and the contrast-to-noise ratio (CNR) of calcifications in the three DE calcification images: image without scatter correction, image with scatter correction using pinhole-array interpolation method, and image with scatter correction using the authors' algorithmic method.Results: The authors' results show that the resultant background DE calcification signal can be reduced. The root-mean-square of background DE calcification signal of 1962 μm with scatter-uncorrected data was reduced to 194 μm after scatter correction using the authors' algorithmic method

  1. Double-aberration corrected TEM/STEM of solid acid nanocatalysts in the development of pharmaceutical NSAIDS

    Science.gov (United States)

    Yoshida, K.; Shiju, N.; Brown, R.; Wright, I.; Boyes, E. D.; Gai, P. L.

    2012-07-01

    We report nanostructural and physico-chemical studies in the development of an efficient low temperature heterogeneous catalytic process for nonsteroidal anti-inflammatory drugs (NSAIDS) such as N-acetyl-p-aminophenol (paracetamol or acetaminophen) on tungstated zirconia nanocatalysts. Using a double-aberration corrected TEM/STEM, modified in-house for in-situ studies at the sub-Angstrom level, we directly observed in real-time, the dynamic precursor transformation to the active catalyst. We quantified the observations with catalytic activity studies for the NSAIDS. The studies have provided the direct evidence for single tungsten promoter atoms and surface WOx species of pharmaceuticals.

  2. Interaction between single gold atom and the graphene edge: A study via aberration-corrected transmission electron microscopy

    KAUST Repository

    Wang, Hongtao

    2012-01-01

    Interaction between single noble metal atoms and graphene edges has been investigated via aberration-corrected and monochromated transmission electron microscopy. A collective motion of the Au atom and the nearby carbon atoms is observed in transition between energy-favorable configurations. Most trapping and detrapping processes are assisted by the dangling carbon atoms, which are more susceptible to knock-on displacements by electron irradiation. Thermal energy is lower than the activation barriers in transition among different energy-favorable configurations, which suggests electron-beam irradiation can be an efficient way of engineering the graphene edge with metal atoms. © 2012 The Royal Society of Chemistry.

  3. Direct imaging of light elements by annular dark-field aberration-corrected scanning transmission electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Lotnyk, Andriy, E-mail: andriy.lotnyk@iom-leipzig.de; Poppitz, David; Gerlach, Jürgen W.; Rauschenbach, Bernd [Leibniz Institute of Surface Modification, Permoserstr. 15, D-04318 Leipzig (Germany)

    2014-02-17

    In this report, we show that an annular dark-field detector in an aberration-corrected scanning transmission electron microscope allows the direct observation of light element columns in crystalline lattices. At specific imaging conditions, an enhancement of the intensities of light element columns in the presence of heavy element columns is observed. Experimental results are presented for imaging the nitrogen and carbon atomic columns at the GaN-SiC interface and within the GaN and SiC compounds. The crystal polarity of GaN at the interface is identified. The obtained findings are discussed and are well supported by image simulations.

  4. Full correction for spatially distributed speed-of-sound in echo ultrasound based on measuring aberration delays via transmit beam steering

    International Nuclear Information System (INIS)

    Aberrations of the acoustic wave front, caused by spatial variations of the speed-of-sound, are a main limiting factor to the diagnostic power of medical ultrasound imaging. If not accounted for, aberrations result in low resolution and increased side lobe level, over all reducing contrast in deep tissue imaging. Various techniques have been proposed for quantifying aberrations by analysing the arrival time of coherent echoes from so-called guide stars or beacons. In situations where a guide star is missing, aperture-based techniques may give ambiguous results. Moreover, they are conceptually focused on aberrators that can be approximated as a phase screen in front of the probe. We propose a novel technique, where the effect of aberration is detected in the reconstructed image as opposed to the aperture data. The varying local echo phase when changing the transmit beam steering angle directly reflects the varying arrival time of the transmit wave front. This allows sensing the angle-dependent aberration delay in a spatially resolved way, and thus aberration correction for a spatially distributed volume aberrator. In phantoms containing a cylindrical aberrator, we achieved location-independent diffraction-limited resolution as well as accurate display of echo location based on reconstructing the speed-of-sound spatially resolved. First successful volunteer results confirm the clinical potential of the proposed technique. (paper)

  5. Orbit correction algorithm for SSRF fast orbit feedback system

    Institute of Scientific and Technical Information of China (English)

    LIU Ming; YIN Chongxian; LIU Dekang

    2009-01-01

    A fast orbit feedback system is designed at SSRF to suppress beam orbit disturbance within sub-micron in the bandwidth up to 100 Hz.The SVD (Singular value decomposition) algorithm is applied to calculate the inverse response matrix in global orbit correction.The number of singular eigenvalues will influence orbit noise suppression and corrector strengths.The method to choose singular eigenvalue rejection threshold is studied in this paper,and the simulation and experiment results are also presented.

  6. Background Simulation and Correction Algorithm in Spot Weld Image Processing

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    One of the chief works for inspecting spot weld quality by X-ray to obtain an ideal and uniform digital image. This paper introduces three methods of image background simulation algorithm, and the effect of background correction was compared. It may be safely said that Kalman filter method is simple and fast for general image; the FFT method has a good adaptability for background simulation.

  7. Bayesian-based aberration correction and numerical diffraction for improved lensfree on-chip microscopy of biological specimens

    CERN Document Server

    Wong, Alexander; Jin, Chao; Wang, Xiao Yu

    2015-01-01

    Lensfree on-chip microscopy is an emerging imaging technique that can be used to visualize and study biological specimens without the need for imaging lens systems. Important issues that can limit the performance of lensfree on-chip microscopy include interferometric aberrations, acquisition noise, and image reconstruction artifacts. In this study, we introduce a Bayesian-based method for performing aberration correction and numerical diffraction that accounts for all three of these issues to improve the effective numerical aperture (NA) and signal-to-noise ratio (SNR) of the reconstructed microscopic image. The proposed method was experimentally validated using the USAF resolution target as well as real waterborne Anabaena flos-aquae samples, demonstrating improvements in NA by ~25% over the standard method, and improvements in SNR of 2.3 dB and 3.8 dB in the reconstructed image when compared to the reconstructed images produced using the standard method and a maximum likelihood estimation method, respective...

  8. Numerical computation of arbitrary order transfer maps and reconstructive correction of aberrations in the large acceptance spectrometer MAGNEX

    Energy Technology Data Exchange (ETDEWEB)

    Shchepunov, V.A. E-mail: shchepun@sunhe.jinr.rushchepunov@lns.infn.it; Cunsolo, A.; Cappuzzello, F.; Foti, A.; Lazzaro, A.; Melita, A.L.; Nociforo, C.; Winfield, J.S

    2003-05-01

    The large angular ({approx}50 msr) and momentum ({approx}20%) acceptance spectrometer MAGNEX is under construction at the South National Laboratories INFN. In the spectrometer, positions of ions in two planes near the focal plane and their vertical positions near the target are measured. The energy resolution of about 1000 is achieved due to the use of the reconstruction of trajectories and reconstructive correction of aberrations. Main features of the spectrometer ion optics are considered. A numerical method of calculation of an arbitrary order transfer map is proposed. In this method, a transfer map is calculated using, as input, initial and final coordinates of a set of rays in an ion-optical system. The rays start at the nods of a regular multi-dimensional mesh in the particle phase space. Rays of the set are chosen automatically according to the order and dimension of the map to be calculated. Final coordinates of the rays are calculated with a regular numerical integration. The proposed is, in fact, a general (ray tracing based) method of calculation of a transfer map, of any order and dimension, for an arbitrary ion-optical system. The method has been used for numerical simulations of the reconstructive correction of aberrations in the MAGNEX spectrometer. Simulation results are considered. A C++ class library has been developed to realize the proposed transfer map calculation method. Elementary operations with vectors and maps, both being C++ objects, are realized as C++ operator functions. The map order is defined by a user at the moment of initialization of the corresponding map object. Its maximum value is limited only by an available computer memory. Computational aspects of the method are discussed in brief.

  9. Flux-corrected transport principles, algorithms, and applications

    CERN Document Server

    Kuzmin, Dmitri; Turek, Stefan

    2005-01-01

    Addressing students and researchers as well as CFD practitioners, this book describes the state of the art in the development of high-resolution schemes based on the Flux-Corrected Transport (FCT) paradigm. Intended for readers who have a solid background in Computational Fluid Dynamics, the book begins with historical notes by J.P. Boris and D.L. Book. Review articles that follow describe recent advances in the design of FCT algorithms as well as various algorithmic aspects. The topics addressed in the book and its main highlights include: the derivation and analysis of classical FCT schemes with special emphasis on the underlying physical and mathematical constraints; flux limiting for hyperbolic systems; generalization of FCT to implicit time-stepping and finite element discretizations on unstructured meshes and its role as a subgrid scale model for Monotonically Integrated Large Eddy Simulation (MILES) of turbulent flows. The proposed enhancements of the FCT methodology also comprise the prelimiting and '...

  10. Multirobot FastSLAM Algorithm Based on Landmark Consistency Correction

    Directory of Open Access Journals (Sweden)

    Shi-Ming Chen

    2014-01-01

    Full Text Available Considering the influence of uncertain map information on multirobot SLAM problem, a multirobot FastSLAM algorithm based on landmark consistency correction is proposed. Firstly, electromagnetism-like mechanism is introduced to the resampling procedure in single-robot FastSLAM, where we assume that each sampling particle is looked at as a charged electron and attraction-repulsion mechanism in electromagnetism field is used to simulate interactive force between the particles to improve the distribution of particles. Secondly, when multiple robots observe the same landmarks, every robot is regarded as one node and Kalman-Consensus Filter is proposed to update landmark information, which further improves the accuracy of localization and mapping. Finally, the simulation results show that the algorithm is suitable and effective.

  11. Aerosol Retrieval and Atmospheric Correction Algorithms for EPIC

    Science.gov (United States)

    Wang, Y.; Lyapustin, A.; Marshak, A.; Korkin, S.; Herman, J. R.

    2011-12-01

    EPIC is a multi-spectral imager onboard planned Deep Space Climate ObserVatoRy (DSCOVR) designed for observations of the full illuminated disk of the Earth with high temporal and coarse spatial resolution (10 km) from Lagrangian L1 point. During the course of the day, EPIC will view the same Earth surface area in the full range of solar and view zenith angles at equator with fixed scattering angle near the backscattering direction. This talk will describe a new aerosol retrieval/atmospheric correction algorithm developed for EPIC and tested with EPIC Simulator data. This algorithm uses the time series approach and consists of two stages: the first stage is designed to periodically re-initialize the surface spectral bidirectional reflectance (BRF) on stable low AOD days. Such days can be selected based on the same measured reflectance between the morning and afternoon reciprocal view geometries of EPIC. On the second stage, the algorithm will monitor the diurnal cycle of aerosol optical depth and fine mode fraction based on the known spectral surface BRF. Testing of the developed algorithm with simulated EPIC data over continental USA showed a good accuracy of AOD retrievals (10-20%) except over very bright surfaces.

  12. Quantitative analysis of interfacial strain in InAs/GaSb superlattices by aberration-corrected HRTEM and HAADF-STEM.

    Science.gov (United States)

    Mahalingam, Krishnamurthy; Haugan, Heather J; Brown, Gail J; Eyink, Kurt G

    2013-04-01

    The strain distribution across interfaces in InAs/GaSb superlattices grown on (100)-GaSb substrates is investigated by aberration corrected transmission electron microscopy. Atomic resolution images of interfaces were obtained by conventional high resolution transmission electron microscopy (HRTEM), using the negative spherical-aberration imaging mode, and by scanning transmission electron microscopy (STEM), using the high-angle annular dark-field (HAADF) imaging mode. The local atomic displacements across interfaces were determined from these images using the peak pair algorithm, from which strain maps were calculated with respect to a reference lattice extracted from the GaSb substrate region. Both techniques yield consistent results, which reveal that the InAs-on-GaSb interface is nearly strain balanced, whereas the GaSb-on-InAs interface is in tensile strain, indicating that the prevalent bond type at this interface is Ga-As. In addition, the GaSb layers in the superlattice are compressively strained indicating the incorporation of In into these layers. Further analysis of the HAADF-STEM images indicates an estimated 4% In content in the GaSb layers and that the GaSb-on-InAs interface contributes to about 27% of the overall superlattice strain. The strain measurements in the InAs layers are in good agreement with the theoretical values determined from elastic constants. Furthermore, the overall superlattice strain determined from this analysis is also in good agreement with the measurements determined by high-resolution X-ray diffraction.

  13. Aberration-corrected scanning transmission electron microscopy for complex transition metal oxides

    Science.gov (United States)

    Qing-Hua, Zhang; Dong-Dong, Xiao; Lin, Gu

    2016-06-01

    Lattice, charge, orbital, and spin are the four fundamental degrees of freedom in condensed matter, of which the interactive coupling derives tremendous novel physical phenomena, such as high-temperature superconductivity (high-T c SC) and colossal magnetoresistance (CMR) in strongly correlated electronic system. Direct experimental observation of these freedoms is essential to understanding the structure-property relationship and the physics behind it, and also indispensable for designing new materials and devices. Scanning transmission electron microscopy (STEM) integrating multiple techniques of structure imaging and spectrum analysis, is a comprehensive platform for providing structural, chemical and electronic information of materials with a high spatial resolution. Benefiting from the development of aberration correctors, STEM has taken a big breakthrough towards sub-angstrom resolution in last decade and always steps forward to improve the capability of material characterization; many improvements have been achieved in recent years, thereby giving an in-depth insight into material research. Here, we present a brief review of the recent advances of STEM by some representative examples of perovskite transition metal oxides; atomic-scale mapping of ferroelectric polarization, octahedral distortions and rotations, valence state, coordination and spin ordering are presented. We expect that this brief introduction about the current capability of STEM could facilitate the understanding of the relationship between functional properties and these fundamental degrees of freedom in complex oxides. Project supported by the National Key Basic Research Project, China (Grant No. 2014CB921002), the Strategic Priority Research Program of Chinese Academy of Sciences (Grant No. XDB07030200), and the National Natural Science Foundation of China (Grant Nos. 51522212 and 51421002).

  14. Goldindec: A Novel Algorithm for Raman Spectrum Baseline Correction

    Science.gov (United States)

    Liu, Juntao; Sun, Jianyang; Huang, Xiuzhen; Li, Guojun; Liu, Binqiang

    2016-01-01

    Raman spectra have been widely used in biology, physics, and chemistry and have become an essential tool for the studies of macromolecules. Nevertheless, the raw Raman signal is often obscured by a broad background curve (or baseline) due to the intrinsic fluorescence of the organic molecules, which leads to unpredictable negative effects in quantitative analysis of Raman spectra. Therefore, it is essential to correct this baseline before analyzing raw Raman spectra. Polynomial fitting has proven to be the most convenient and simplest method and has high accuracy. In polynomial fitting, the cost function used and its parameters are crucial. This article proposes a novel iterative algorithm named Goldindec, freely available for noncommercial use as noted in text, with a new cost function that not only conquers the influence of great peaks but also solves the problem of low correction accuracy when there is a high peak number. Goldindec automatically generates parameters from the raw data rather than by empirical choice, as in previous methods. Comparisons with other algorithms on the benchmark data show that Goldindec has a higher accuracy and computational efficiency, and is hardly affected by great peaks, peak number, and wavenumber. PMID:26037638

  15. Holographic Properties of BR-D96N Film and Its Application in Hologram Aberration Correction

    Institute of Scientific and Technical Information of China (English)

    ZHENG Yuan(郑媛); YAO Bao-Li(姚保利); WANG Ying-Li(王英利); MENKE Neimule(门克内木乐); LEI Ming(雷铭); CHEN Guo-Fu(陈国夫); Norbert HAMPP

    2003-01-01

    A biophotochromic material, i.e., genetic mutant bacteriorhodopsin (BR-D96N), was experimentally studied on its holographic recording properties. The saturation absorption curve and the diffraction efficiency curve were measured respectively. As holographic storage application, reflection type polarization holograms were recorded on the BR-D96N film. The 173° configuration between the object and reference beams proves that the spatial resolution of the film is over 6000 lines/mm. By using phase conjugate wave of reference beam as reconstruction beam, the distorted object image introduced by the optical components and the defects in the recording medium can be well corrected.

  16. Detection of Single Atoms and Buried Defects in Three Dimensions by Aberration-corrected Electron Microscope with 0.5 ? Information Limit

    Energy Technology Data Exchange (ETDEWEB)

    Kisielowski, Christian [University of California, Berkeley; Bischoff, Maarten [FEI Company, The Netherlands; van Lin, Hans [FEI Company, The Netherlands; Lazar, Sorin [FEI Company, The Netherlands; Freitag, Bernhard [FEI Company, The Netherlands; Knippels, Georg [FEI Company, The Netherlands; Tiemeijer, Peter [FEI Company, The Netherlands; van der Stam, Maarten [FEI Company, The Netherlands; von Harrach, Sebastian [FEI Company, The Netherlands; Stekelenburg, Michael [FEI Company, The Netherlands; Haider, Maximilian [CEOS GmbH, Heidelberg, Germany; M�ller, Hans [CEOS GmbH, Heidelberg, Germany; Hartel, Peter [CEOS GmbH, Heidelberg, Germany; Kabius, Bernd [Argonne National Laboratory (ANL); Miller, Dean [Argonne National Laboratory (ANL); Petrov, Ivan [University of Illinois, Urbana-Champaign; Olson, Eric [University of Illinois, Urbana-Champaign; Donchev, Tomas [University of Illinois, Urbana-Champaign; Kenik, Edward A [ORNL; Lupini, Andrew R [ORNL; Bentley, James [ORNL; Pennycook, Stephen J [ORNL; Minor, Andrew [Lawrence Berkeley National Laboratory (LBNL); Schmid, Andreas [Lawrence Berkeley National Laboratory (LBNL); Duden, Thomas [Lawrence Berkeley National Laboratory (LBNL); Radmilovic, Velimir [Lawrence Berkeley National Laboratory (LBNL); Ramasse, Quentin [Lawrence Berkeley National Laboratory (LBNL); Watanabe, Masashi [Lawrence Berkeley National Laboratory (LBNL); Stach, Eric [Lawrence Berkeley National Laboratory (LBNL); Denes, Peter [Lawrence Berkeley National Laboratory (LBNL); Dahmen, Ulrich [Lawrence Berkeley National Laboratory (LBNL)

    2008-01-01

    The ability of electron microscopes to analyze all the atoms in individual nanostructures is limited by lens aberrations. However, recent advances in aberration-correcting electron optics have led to greatly enhanced instrument performance and new techniques of electron microscopy. The development of an ultrastable electron microscope with aberration-correcting optics and a monochromated high-brightness source has significantly improved instrument resolution and contrast. In the present work, we report information transfer beyond 50 pm and show images of single gold atoms with a signal-to-noise ratio as large as 10. The instrument's new capabilities were exploited to detect a buried Σ3 {112} grain boundary and observe the dynamic arrangements of single atoms and atom pairs with sub- ngstrom resolution. These results mark an important step toward meeting the challenge of determining the 3D atomic-scale structure of nanomaterials.

  17. Lowered threshold energy for femtosecond laser induced optical breakdown in a water based eye model by aberration correction with adaptive optics.

    Science.gov (United States)

    Hansen, Anja; Géneaux, Romain; Günther, Axel; Krüger, Alexander; Ripken, Tammo

    2013-06-01

    In femtosecond laser ophthalmic surgery tissue dissection is achieved by photodisruption based on laser induced optical breakdown. In order to minimize collateral damage to the eye laser surgery systems should be optimized towards the lowest possible energy threshold for photodisruption. However, optical aberrations of the eye and the laser system distort the irradiance distribution from an ideal profile which causes a rise in breakdown threshold energy even if great care is taken to minimize the aberrations of the system during design and alignment. In this study we used a water chamber with an achromatic focusing lens and a scattering sample as eye model and determined breakdown threshold in single pulse plasma transmission loss measurements. Due to aberrations, the precise lower limit for breakdown threshold irradiance in water is still unknown. Here we show that the threshold energy can be substantially reduced when using adaptive optics to improve the irradiance distribution by spatial beam shaping. We found that for initial aberrations with a root-mean-square wave front error of only one third of the wavelength the threshold energy can still be reduced by a factor of three if the aberrations are corrected to the diffraction limit by adaptive optics. The transmitted pulse energy is reduced by 17% at twice the threshold. Furthermore, the gas bubble motions after breakdown for pulse trains at 5 kilohertz repetition rate show a more transverse direction in the corrected case compared to the more spherical distribution without correction. Our results demonstrate how both applied and transmitted pulse energy could be reduced during ophthalmic surgery when correcting for aberrations. As a consequence, the risk of retinal damage by transmitted energy and the extent of collateral damage to the focal volume could be minimized accordingly when using adaptive optics in fs-laser surgery.

  18. Canopy induced aberration correction in airborne electro-optical imaging systems

    Science.gov (United States)

    Harder, James A.; Sprague, Michaelene W.

    2011-11-01

    An increasing number of electro-optical systems are being used by pilots in tactical aircraft. This means that the afore mentioned systems must operate through the aircrafts canopy, unfortunately the canopy functions as a less than ideal lens element in the electro-optical sensor optical path. The canopy serves first and foremost as an aircraft structural component, considerations like minimizing the drag co-efficient and the ability to survive bird strikes take precedence over achieving optimal optical characteristics. This paper describes how the authors characterized the optical characteristics of an aircraft canopy. Families of modulation transfer functions were generated, for various viewing geometries through the canopy and for various electro-optical system entrance pupil diameters. These functions provided us with the means to significantly reduce the effect of the canopy "lens" on the performance of a representative electro-optical system, using an Astigmatic Corrector Lens. A comparison of the electro-optical system performance with and without correction is also presented.

  19. Correção das aberrações oculares nos retratamentos de LASIK personalizado e convencional Correction of ocular aberrations in custom and standard LASIK retreatments

    Directory of Open Access Journals (Sweden)

    Andréia Peltier Urbano

    2009-10-01

    Full Text Available OBJETIVO: Comparar a correção das aberrações oculares nos retratamentos de LASIK personalizado e convencional. MÉTODOS: Foi realizado um estudo prospectivo, randomizado, de 74 olhos de 37 pacientes submetidos ao retratamento de LASIK para correção de miopia e astigmatismo. Cada paciente foi submetido ao retratamento de LASIK personalizado Zyoptix (Bausch & Lomb em um olho e convencional Planoscan (Bausch & Lomb no olho contralateral. Foi comparada a correção das aberrações oculares nos retratamentos personalizado e convencional. RESULTADOS: No sexto mês pós-operatório, os olhos submetidos ao retratamento Zyoptix apresentaram diminuição estatisticamente significativa do defocus, astigmatismo, coma, aberração esférica, segunda ordem, terceira ordem, alta ordem e aberrações totais. Os olhos submetidos ao retratamento Planoscan apresentaram diminuição estatisticamente significativa do defocus, segunda ordem e aberrações totais. CONCLUSÕES: O retratamento personalizado foi superior ao retratamento convencional para a correção das aberrações oculares de baixa e alta ordens.PURPOSE: To compare the correction of ocular aberrations between custom and standard LASIK retreatment. METHODS: Prospective, randomized trial with paired eye control of 74 eyes from 37 patients who underwent LASIK retreatment. Each patient underwent retreatment using Zyoptix LASIK (Bausch & Lomb in 1 eye and Planoscan LASIK (Bausch & Lomb in the fellow eye. Correction of ocular aberrations was compared between custom and standard LASIK retreatments. RESULTS: At 6 months, there was a statistically significant reduction in defocus, astigmatism, coma, spherical aberration, second, third, higher-order and total aberration in Zyoptix eyes. There was a statistically significant reduction in defocus, second-order and total aberration in Planoscan eyes. CONCLUSIONS: Custom retreatment was statistically superior than standard retreatment for correction of lower

  20. Flux-corrected transport principles, algorithms, and applications

    CERN Document Server

    Löhner, Rainald; Turek, Stefan

    2012-01-01

    Many modern high-resolution schemes for Computational Fluid Dynamics trace their origins to the Flux-Corrected Transport (FCT) paradigm. FCT maintains monotonicity using a nonoscillatory low-order scheme to determine the bounds for a constrained high-order approximation. This book begins with historical notes by J.P. Boris and D.L. Book who invented FCT in the early 1970s. The chapters that follow describe the design of fully multidimensional FCT algorithms for structured and unstructured grids, limiting for systems of conservation laws, and the use of FCT as an implicit subgrid scale model. The second edition presents 200 pages of additional material. The main highlights of the three new chapters include: FCT-constrained interpolation for Arbitrary Lagrangian-Eulerian methods, an optimization-based approach to flux correction, and FCT simulations of high-speed flows on overset grids. Addressing students and researchers, as well as CFD practitioners, the book is focused on computational aspects and contains m...

  1. Numerical computation of arbitrary order transfer maps and reconstructive correction of aberrations in the large acceptance spectrometer MAGNEX

    CERN Document Server

    Shchepunov, V A; Cappuzzello, F; Foti, A; Lazzaro, A; Melita, A L; Nociforo, C; Winfield, J S

    2003-01-01

    The large angular (approx 50 msr) and momentum (approx 20%) acceptance spectrometer MAGNEX is under construction at the South National Laboratories INFN. In the spectrometer, positions of ions in two planes near the focal plane and their vertical positions near the target are measured. The energy resolution of about 1000 is achieved due to the use of the reconstruction of trajectories and reconstructive correction of aberrations. Main features of the spectrometer ion optics are considered. A numerical method of calculation of an arbitrary order transfer map is proposed. In this method, a transfer map is calculated using, as input, initial and final coordinates of a set of rays in an ion-optical system. The rays start at the nods of a regular multi-dimensional mesh in the particle phase space. Rays of the set are chosen automatically according to the order and dimension of the map to be calculated. Final coordinates of the rays are calculated with a regular numerical integration. The proposed is, in fact, a ge...

  2. Quantitative analysis of interfacial strain in InAs/GaSb superlattices by aberration-corrected HRTEM and HAADF-STEM

    Energy Technology Data Exchange (ETDEWEB)

    Mahalingam, Krishnamurthy, E-mail: Krishnamurthy.Mahalingam.ctr@wpafb.af.mil [Air Force Research Laboratory, Wright-Patterson AFB, OH 45433-7707 (United States); Haugan, Heather J.; Brown, Gail J.; Eyink, Kurt G. [Air Force Research Laboratory, Wright-Patterson AFB, OH 45433-7707 (United States)

    2013-04-15

    The strain distribution across interfaces in InAs/GaSb superlattices grown on (100)-GaSb substrates is investigated by aberration corrected transmission electron microscopy. Atomic resolution images of interfaces were obtained by conventional high resolution transmission electron microscopy (HRTEM), using the negative spherical-aberration imaging mode, and by scanning transmission electron microscopy (STEM), using the high-angle annular dark-field (HAADF) imaging mode. The local atomic displacements across interfaces were determined from these images using the peak pair algorithm, from which strain maps were calculated with respect to a reference lattice extracted from the GaSb substrate region. Both techniques yield consistent results, which reveal that the InAs-on-GaSb interface is nearly strain balanced, whereas the GaSb-on-InAs interface is in tensile strain, indicating that the prevalent bond type at this interface is Ga–As. In addition, the GaSb layers in the superlattice are compressively strained indicating the incorporation of In into these layers. Further analysis of the HAADF-STEM images indicates an estimated 4% In content in the GaSb layers and that the GaSb-on-InAs interface contributes to about 27% of the overall superlattice strain. The strain measurements in the InAs layers are in good agreement with the theoretical values determined from elastic constants. Furthermore, the overall superlattice strain determined from this analysis is also in good agreement with the measurements determined by high-resolution X-ray diffraction. - Highlights: ►The strain distribution across interfaces in InAs–GaSb superlattices is examined. ► The GaSb-on-InAs interfaces are tensile, accounting for 27% of the overall strain. ► The InAs-on-GaSb interfaces are strain neutral. ► The GaSb layers are in compressive strain due to indium incorporation of about 4%. ► The strain in InAs layers is tensile, and is close to the bulk value of about 1%.

  3. J2 invariant relative orbits via differential correction algorithm

    Institute of Scientific and Technical Information of China (English)

    Ming Xu; Shijie Xu

    2007-01-01

    This paper describes a practical method for finding the invariant orbits in J2 relative dynamics. Working with the Hamiltonian model of the relative motion in cludingthe J2 perturbation, the effective differential correction algorithm for finding periodic orbits in three-body problem is extended to formation flying of Earth's orbiters. Rather than using orbital elements, the analysis is done directly in physical space, which makes a direct connection with physical requirements. The asymptotic behavior of the invariant orbit is indicated by its stable and unstable manifolds. The period of the relative orbits is proved numerically to be slightly different from the ascending node period of the leader satellite,and a preliminary explanation for this phenomenon is presented. Then the compatibility between J2 invariant orbit and desired relative geometry is considered, and the design procedure for the initial values of the compatible configurationis proposed. The influences of measure errors on the invariantorbit are also investigated by the Monte-Carlo simulation.

  4. Magnetic liquid deformable mirrors for astronomical applications:Active correction of optical aberrations from lower-grade optics and support system

    CERN Document Server

    Borra, E F

    2012-01-01

    Deformable mirrors are increasingly used in astronomy. However, they still are limited in stroke for active correction of high amplitude optical aberrations. Magnetic Liquid deformable mirrors (MLDMs) are a new technology that has advantages of high-amplitude deformations and low costs. In this paper we demonstrate extremely high strokes and inter-actuator strokes achievable by MLDMs which can be used in astronomical instrumentation. In particular, we consider the use of such a mirror to suggest an interesting application for the next generation of large telescopes. We present a prototype 91-actuator deformable mirror made of a magnetic liquid (ferrofluid). This mirror uses a technique that linearizes the response of such mirrors by superimposing a large and uniform magnetic field to the magnetic field produced by an array of small coils. We discuss experimental results that illustrate the performance of MLDMs. A most interesting application of MLDMs comes from the fact they could be used to correct the aberr...

  5. Design and Performance Characteristics of the ORNL Advanced Microscopy Laboratory and JEOL 2200FS-AC Aberration-Corrected STEM/TEM

    OpenAIRE

    Lawrence F. Allard; Douglas A. Blom; O'Keefe, Michael A.; Mishina, S.

    2005-01-01

    At ORNL, the new Advanced Microscopy Laboratory (AML) has recently been completed, with two aberration-corrected instruments installed, and two more planned in the near future to fill the 4-laboratory building. The installed JEOL 2200FS-AC has demonstrated a TEM information limit of 0.9A. This limit is expected given the measured instrument parameters (HT and OL power supply stabilities, beam energy spread, etc.), and illustrates that the environmental influences are not adversely affect...

  6. An algorithm for the treatment of schizophrenia in the correctional setting: the Forensic Algorithm Project.

    Science.gov (United States)

    Buscema, C A; Abbasi, Q A; Barry, D J; Lauve, T H

    2000-10-01

    The Forensic Algorithm Project (FAP) was born of the need for a holistic approach in the treatment of the inmate with schizophrenia. Schizophrenia was chosen as the first entity to be addressed by the algorithm because of its refractory nature and high rate of recidivism in the correctional setting. Schizophrenia is regarded as a spectrum disorder, with symptom clusters and behaviors ranging from positive to negative symptoms to neurocognitive dysfunction and affective instability. Furthermore, the clinical picture is clouded by Axis II symptomatology (particularly prominent in the inmate population), comorbid Axis I disorders, and organicity. Four subgroups of schizophrenia were created to coincide with common clinical presentations in the forensic inpatient facility and also to parallel 4 tracks of intervention, consisting of pharmacologic management and programming recommendations. The algorithm begins with any antipsychotic medication and proceeds to atypical neuroleptic usage, augmentation with other psychotropic agents, and, finally, the use of clozapine as the common pathway for refractory schizophrenia. Outcome measurement of pharmacologic intervention is assessed every 6 weeks through the use of a 4-item subscale, specific for each forensic subgroup. A "floating threshold" of 40% symptom severity reduction on Positive and Negative Syndrome Scale and Brief Psychiatric Rating Scale items over a 6-week period is considered an indication for neuroleptic continuation. The forensic algorithm differs from other clinical practice guidelines in that specific programming in certain prison environments is stipulated. Finally, a social commentary on the importance of state-of-the-art psychiatric treatment for all members of society is woven into the clinical tapestry of this article. PMID:11078038

  7. In-situ Study of Dynamic Phenomena at Metal Nanosolder Interfaces Using Aberration Corrected Scanning Transmission Electron Microcopy.

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Ping

    2014-10-01

    Controlling metallic nanoparticle (NP) interactions plays a vital role in the development of new joining techniques (nanosolder) that bond at lower processing temperatures but remain viable at higher temperatures. The pr imary objective of this project is t o develop a fundamental understanding of the actual reaction processes, associated atomic mechanisms, and the resulting microstructure that occur during thermally - driven bond formation concerning metal - metal nano - scale (%3C50nm) interfaces. In this LDRD pr oject, we have studied metallic NPs interaction at the elevated temperatures by combining in - situ transmission electron microscopy (TEM ) using an aberration - corrected scanning transmission electron microscope (AC - STEM) and atomic - scale modeling such as m olecular dynamic (MD) simulations. Various metallic NPs such as Ag, Cu and Au are synthesized by chemical routines. Numerous in - situ e xperiments were carried out with focus of the research on study of Ag - Cu system. For the first time, using in - situ STEM he ating experiments , we directly observed t he formation of a 3 - dimensional (3 - D) epitaxial Cu - Ag core - shell nanoparticle during the thermal interaction of Cu and Ag NPs at elevated temperatures (150 - 300 o C). The reaction takes place at temperatures as low as 150 o C and was only observed when care was taken to circumvent the effects of electron beam irradiation during STEM imaging. Atomic - scale modeling verified that the Cu - Ag core - shell structure is energetically favored, and indicated that this phenomenon is a nano - scale effect related to the large surface - to - volume ratio of the NPs. The observation potentially can be used for developing new nanosolder technology that uses Ag shell as the "glue" that stic ks the particles of Cu together. The LDRD has led to several journal publications and numerous conference presentations, and a TA. In addition, we have developed new TEM characterization techniques and phase

  8. Study on battery state of charge correct algorithm of electric vehicle

    Institute of Scientific and Technical Information of China (English)

    KAN Ping; QIAN Lijun

    2012-01-01

    State of Charge (SOC) is used to adjust the initialization SOC value so as to make electric vehicle simulation results close to real vehicle performance. This paper firstly analyses the battery SOC correct algorithm, then uses ADVISOR which is a electric vehicle simulation software to simulate a hybrid electric car with three different cases of no SOC correct, linear SOC correct and zero delta SOC correct, as well as makes the compare and analysis for those simulation results. In the end, an overall conclusion to SOC correct algorithm is given.

  9. Temporal high-pass non-uniformity correction algorithm based on grayscale mapping and hardware implementation

    Science.gov (United States)

    Jin, Minglei; Jin, Weiqi; Li, Yiyang; Li, Shuo

    2015-08-01

    In this paper, we propose a novel scene-based non-uniformity correction algorithm for infrared image processing-temporal high-pass non-uniformity correction algorithm based on grayscale mapping (THP and GM). The main sources of non-uniformity are: (1) detector fabrication inaccuracies; (2) non-linearity and variations in the read-out electronics and (3) optical path effects. The non-uniformity will be reduced by non-uniformity correction (NUC) algorithms. The NUC algorithms are often divided into calibration-based non-uniformity correction (CBNUC) algorithms and scene-based non-uniformity correction (SBNUC) algorithms. As non-uniformity drifts temporally, CBNUC algorithms must be repeated by inserting a uniform radiation source which SBNUC algorithms do not need into the view, so the SBNUC algorithm becomes an essential part of infrared imaging system. The SBNUC algorithms' poor robustness often leads two defects: artifacts and over-correction, meanwhile due to complicated calculation process and large storage consumption, hardware implementation of the SBNUC algorithms is difficult, especially in Field Programmable Gate Array (FPGA) platform. The THP and GM algorithm proposed in this paper can eliminate the non-uniformity without causing defects. The hardware implementation of the algorithm only based on FPGA has two advantages: (1) low resources consumption, and (2) small hardware delay: less than 20 lines, it can be transplanted to a variety of infrared detectors equipped with FPGA image processing module, it can reduce the stripe non-uniformity and the ripple non-uniformity.

  10. Correction of oral contrast artifacts in CT-based attenuation correction of PET images using an automated segmentation algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Ahmadian, Alireza; Ay, Mohammad R.; Sarkar, Saeed [Medical Sciences/University of Tehran, Research Center for Science and Technology in Medicine, Tehran (Iran); Medical Sciences/University of Tehran, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran (Iran); Bidgoli, Javad H. [Medical Sciences/University of Tehran, Research Center for Science and Technology in Medicine, Tehran (Iran); East Tehran Azad University, Department of Electrical and Computer Engineering, Tehran (Iran); Zaidi, Habib [Geneva University Hospital, Division of Nuclear Medicine, Geneva (Switzerland)

    2008-10-15

    Oral contrast is usually administered in most X-ray computed tomography (CT) examinations of the abdomen and the pelvis as it allows more accurate identification of the bowel and facilitates the interpretation of abdominal and pelvic CT studies. However, the misclassification of contrast medium with high-density bone in CT-based attenuation correction (CTAC) is known to generate artifacts in the attenuation map ({mu}map), thus resulting in overcorrection for attenuation of positron emission tomography (PET) images. In this study, we developed an automated algorithm for segmentation and classification of regions containing oral contrast medium to correct for artifacts in CT-attenuation-corrected PET images using the segmented contrast correction (SCC) algorithm. The proposed algorithm consists of two steps: first, high CT number object segmentation using combined region- and boundary-based segmentation and second, object classification to bone and contrast agent using a knowledge-based nonlinear fuzzy classifier. Thereafter, the CT numbers of pixels belonging to the region classified as contrast medium are substituted with their equivalent effective bone CT numbers using the SCC algorithm. The generated CT images are then down-sampled followed by Gaussian smoothing to match the resolution of PET images. A piecewise calibration curve was then used to convert CT pixel values to linear attenuation coefficients at 511 keV. The visual assessment of segmented regions performed by an experienced radiologist confirmed the accuracy of the segmentation and classification algorithms for delineation of contrast-enhanced regions in clinical CT images. The quantitative analysis of generated {mu}maps of 21 clinical CT colonoscopy datasets showed an overestimation ranging between 24.4% and 37.3% in the 3D-classified regions depending on their volume and the concentration of contrast medium. Two PET/CT studies known to be problematic demonstrated the applicability of the technique

  11. Algorithms for Relative Radiometric Correction in Earth Observing Systems Resource-P and Canopus-V

    Science.gov (United States)

    Zenin, V. A.; Eremeev, V. V.; Kuznetcov, A. E.

    2016-06-01

    The present paper has considered two algorithms of the relative radiometric correction of information obtained from a multimatrix imagery instrument of the spacecraft "Resource-P" and frame imagery systems of the spacecraft "Canopus-V". The first algorithm is intended for elimination of vertical stripes on the image that are caused by difference in transfer characteristics of CCD matrices and CCD detectors. Correction coefficients are determined on the basis of analysis of images that are homogeneous by brightness. The second algorithm ensures an acquisition of microframes homogeneous by brightness from which seamless images of the Earth surface are synthesized. Examples of practical usage of the developed algorithms are mentioned.

  12. QR Code Image Correction based on Corner Detection and Convex Hull Algorithm

    Directory of Open Access Journals (Sweden)

    Suran Kong

    2013-12-01

    Full Text Available Since the angular deviation produced when shooting a QR code image by a camera would cause geometric distortion of the QR code image, the traditional algorithm of QR code image correction would produce distortion. Therefore this paper puts forward the algorithm which combines corner detection with convex hull algorithm. Firstly, binaryzation of the collected QR code image with uneven light is obtained by the methods of local threshold and mathematical morphology. Next, the outline of the QR code and the dots on it are found and the distorted image is recovered by perspective collineation, according to the algorithm raised by this paper. Finally, experimental verification is made that the algorithm raised by this paper can correctly find the four apexes of QR code and achieves good effects of geometric correction. It will also significantly increase the recognition rate of seriously distorted QR code images

  13. Effects of different contact lens correction on Zernike aberrations of human eye%不同角膜接触镜对人眼Zernike像差的影响

    Institute of Scientific and Technical Information of China (English)

    保金华; 贺极苍; 毛欣杰; 吕帆

    2013-01-01

    Background Even though the change in wavefront aberrations with correction modality is well documented in the literature,little is known about the underlying mechanism.Complete understanding of the causes responsible for the wavefront change in the combined lens-eye system is important since it provides basic knowledge for further improving the technique to correct refractive error by correcting lenses.Objective The aim of this study was to investigate the influence of refractive correction lens on optical property of the eye by analyzing Zernike aberrations in myopic eyes with contact lens correction.Methods This study was approved by the Ethic Committee of Wenzhou Medical College.Written informed consent was obtained from each subject before entering this study.Zernike aberrations of 52 myopic eyes of 26 subjects with the spherical equivalent-1.75 to-8.50 D were measured using a Hartmann-Shock wavefront sensor.The human eye aberrations were examined at the uncorrected condition,rigid-gas-permeable contact lens (RGP-CL) corrected condition and soft contact lens (Soft-CL) corrected condition.The differences of wavefront aberrations and Zernike coefficients were compared by repeated measurement of single factor variance analysis,and correlation of the aberration changes between uncorrected condition and RGP-CL corrected condition or Sofi-CL corrected condition,between the right eyes and left eyes in different conditions were analyzed by Pearson linear correlation.Results Mean total root-mean-square (tRMS) was (0.71 ± 0.30)μm,(0.54±0.19)μm and (0.74±0.32)μm in the uncorrected condition,RGP-CL corrected condition and Soft-CL corrected condition,with a significant difference (F =8.758,P<0.001),and tRMS was significant declined under the RGP-CL corrected condition compared with uncorrected condition (t =2.746,P =0.008),and tRMS in RGP-CL corrected condition was significantly lower than that in Soft-CL corrected condition (t =3.428,P =0.001).The high RMS (h

  14. Weighted SVD algorithm for close-orbit correction and 10 Hz feedback in RHIC

    Energy Technology Data Exchange (ETDEWEB)

    Liu C.; Hulsart, R.; Marusic, A.; Michnoff, R.; Minty, M.; Ptitsyn, V.

    2012-05-20

    Measurements of the beam position along an accelerator are typically treated equally using standard SVD-based orbit correction algorithms so distributing the residual errors, modulo the local beta function, equally at the measurement locations. However, sometimes a more stable orbit at select locations is desirable. In this paper, we introduce an algorithm for weighting the beam position measurements to achieve a more stable local orbit. The results of its application to close-orbit correction and 10 Hz orbit feedback are presented.

  15. Operative correction of ocular aberrations to improve visual acuity%波前像差引导的LASIK术矫正眼球像差

    Institute of Scientific and Technical Information of China (English)

    Theo Seiler; Michael Mrochen; Maik Kaemmerer

    2001-01-01

    目的:观察波前像差引导的LASIK术矫正人眼像差后的效果,以确定人眼是否可获得超过一般的视敏度。方法:波前像差引导的LASIK手术对15只眼矫正近视和散光,同时矫正眼球的像差。结果:手术后1个月时,4只眼(占27%)获得了20/10以上的超常视力。波前像差的均方根值从0.6增加到2.3,与视觉敏感度的提高呈显著性相关(P<0.05)。结论:像差的矫正虽然还不能最令人满意,但这些结果表明,眼球的像差使人眼视敏度受限制,而通过手术矫正可获得超过一般的视敏度。%Objective:Optical aberrations of the human eye degrade the quality of the retinal image and may,therefore,represent a major limit of visual acuity.Methods:In 15 eyes,ocular aberrations were corrected in addition to myopia and astigmatism by means of wavefront-guided laser in situ keratomileusis(LASIK).Results:At 1 month after surgery,a supernormal visual acuity of 20/10 or better was obtained in 4 eyes(27%). The increase in root mean square wavefront error ranged from 0.6 to 2.3 and was significantly correlated with the increase in visual acuity(P<0.05).Conclusion:Although the correction of aberrations was not yet optimal,these results show that ocular optical aberrations limit visual acuity in humans and supernormal visual acuity can be achieved by operative correction.

  16. FAILURE CORRECTION OF LINEAR ARRAY ANTENNA WITH MULTIPLE NULL PLACEMENT USING CUCKOO SEARCH ALGORITHM

    OpenAIRE

    Muralidaran, R.; A. Vallavaraj; Hemant Patidar; Mahanti, G. K.

    2014-01-01

    The influence of evolutionary algorithms enhanced its scope of getting its existence in almost every complex optimization problems. In this paper, cuckoo search algorithm, an algorithm based on the brood parasite behavior along with Levy weights has been proposed for the radiation pattern correction of a linear array of isotropic antennas with uniform spacing when failed with more than one antenna element. Even though deterioration produced by the failure of antenna elements results in variou...

  17. QR Code Image Correction based on Corner Detection and Convex Hull Algorithm

    OpenAIRE

    Suran Kong

    2013-01-01

    Since the angular deviation produced when shooting a QR code image by a camera would cause geometric distortion of the QR code image, the traditional algorithm of QR code image correction would produce distortion. Therefore this paper puts forward the algorithm which combines corner detection with convex hull algorithm. Firstly, binaryzation of the collected QR code image with uneven light is obtained by the methods of local threshold and mathematical morphology. Next, the outline of the QR c...

  18. A Genetic Algorithm for Chromaticity Correction in Diffraction Limited Storage Rings

    CERN Document Server

    Ehrlichman, Michael

    2016-01-01

    An multi-objective genetic algorithm is developed for optimizing nonlinearities in diffraction limited storage rings. This algorithm determines sextupole and octupole strengths for chromaticity correction that deliver optimized dynamic aperture and beam lifetime. The algorithm makes use of dominance constraints to breed desirable properties into the early generations. The momentum aperture is optimized indirectly by constraining the chromatic tune footprint and optimizing the off-energy dynamic aperture. The result is an effective and computationally efficient technique for correcting chromaticity in a storage ring while maintaining optimal dynamic aperture and beam lifetime. This framework was developed for the Swiss Light Source (SLS) upgrade project.

  19. Post-Editing Error Correction Algorithm for Speech Recognition using Bing Spelling Suggestion

    CERN Document Server

    Bassil, Youssef

    2012-01-01

    ASR short for Automatic Speech Recognition is the process of converting a spoken speech into text that can be manipulated by a computer. Although ASR has several applications, it is still erroneous and imprecise especially if used in a harsh surrounding wherein the input speech is of low quality. This paper proposes a post-editing ASR error correction method and algorithm based on Bing's online spelling suggestion. In this approach, the ASR recognized output text is spell-checked using Bing's spelling suggestion technology to detect and correct misrecognized words. More specifically, the proposed algorithm breaks down the ASR output text into several word-tokens that are submitted as search queries to Bing search engine. A returned spelling suggestion implies that a query is misspelled; and thus it is replaced by the suggested correction; otherwise, no correction is performed and the algorithm continues with the next token until all tokens get validated. Experiments carried out on various speeches in differen...

  20. Correction of chromatic aberration for human eyes with diffractive-refractive hybrid elements%应用折-衍射元件校正人眼色差

    Institute of Scientific and Technical Information of China (English)

    张梅; 耿征

    2012-01-01

    A chromatic corrector with two refractive-diffractive hybrid elements is designed for a wide field-of- view of 14° to correct chromatic aberrations in human eyes. The performance of the corrector based on several optical criteria is compared with a chromatic eorrector with single refractive-diffractive element. Results show that both correctors can correct for Longitudinal Chromatic Aberration(LCA). However, it is demonstrated that the chromatic corrector with a single element introduces serious eccentric Transverse Chromatic Aberration (TCA) that increases from 14. 61μm to 81.4μm. This deteriorates the image quality at the edge field-of- view. On the chromatic eorreetor with two refractive-diffractive elements, both the LCA and the TCA can be corrected and the TCA is just 1.64μm. The designed chromatic corrector can be used to improve the retinal image quality and has potential applications in the design of visual instruments.%提出了采用两个折射-衍射元件对人眼系统在14°范围内进行色差校正的光学系统设计方法。基于系统光学性能的评价与单片折射-衍射元件色差校正系统的对比验证了本文提出的色差校正系统的性能。结果表明:两种色差校正系统都可以很好地校正人眼的轴向色差。但是,单片折射一衍射色差校正系统引入了横向色差,其由校正前的14.51μm增加到81.4μm,严重影响了边缘视场处的成像质量。而采用双片折射一衍射元件的色差校正系统可同时对轴向色差和横向色差进行校正,使横向色差降为1.64μm。设计的色差校正系统可有效提高视网膜的成像质量,并可用于视觉仪器。

  1. Method for lower order aberration correction based on beam shaping%基于整形光路的低阶像差校正方法

    Institute of Scientific and Technical Information of China (English)

    郭建增; 刘铁根; 王振华; 刘现魁; 韦承甫

    2012-01-01

    To meet the requirements for far-field laser beam irradiation strength, and reduce the impact of thermal effect on the output beam performance, this paper introduces a lower order aberration correction method based on beam shaping. According to the beam wavefront distortion, the method dynamically adjusts the space between shaping mirrors to produce opposite aberrations to correct the aberrations of the first four orders, through the rapid action of the high-precision translation stage and the fast steering mirror, and then the output beam recovers and emits parallelly. The method significantly reduces the thermal drift and thermal distortion of the laser beam, and avoid the long-time continuous beam radiation while running. It features large correction range, control convenience and compact structure, and can greatly improve the quality of the laser output beam and the effect of the laser beam far-field.%为满足激光束对远处目标辐照强度的要求,减小热效应对输出光束性能的影响,提出了一种基于整形光路的高能激光低阶像差校正方法.该方法根据波前探测器测到的光束波前畸变,利用激光器整形光路同有的光学元件和调整机构,通过高精密电动平移台和快反镜的快速动作,动态调整各镜片的间距,实时校正激光束的低阶像差,使输出光束恢复至平行出射,从而显著减小激光束的热漂移和热畸变,有效避免了长时间出光时光束的持续发散,极大改善了输出光束性能.试验结果表明,该方法具有校正量大、控制方便、结构紧凑等优点,能够很好地改善激光器输出光束质量,显著提高激光束远场作用效果.

  2. Nonuniformity correction algorithm with nonlinear model for infrared focal plane arrays

    Science.gov (United States)

    Zhou, Hui-xin; Qin, Han-lin; Bai, Li-ping; Liu, Qun-chang; Geng, Xu; Wang, Bin-jian

    2010-01-01

    For the detector in infrared focal plane arrays (IRFPA) with a large dynamic range of response, a nonlinear model of response curve of the detector in IRFPA is introduced in this paper. With the model, the Kalman-filter nonuniformity correction (NUC) algorithm with linear model, developed by Torres and Hayat, is extended. In the extended algorithm, the raw image is translated into a linearized one firstly by directly employing a logarithm-based transformation. Then the linearized image is corrected by the Kalman-filter NUC algorithm with linear model, and the corrected linearized image is obtained. Finally the uniformity image of the original one is achieved by fulfilling an exponent transformation to the corrected linearized image. The presented algorithm not only inherits the advantage of the original algorithm that resolves the problem of the temporal drift in the gain and the bias in each detector by updating NUC parameters with information of the current scene, but also reduce the influence of the detector nonlinear response to the NUC performance, so it is suitable for IRFPA under large response-range. The NUC ability of the presented algorithm is demonstrated by experiments with real infrared image sequences.

  3. An Uneven Illumination Correction Algorithm for Optical Remote Sensing Images Covered with Thin Clouds

    Directory of Open Access Journals (Sweden)

    Xiaole Shen

    2015-09-01

    Full Text Available The uneven illumination phenomenon caused by thin clouds will reduce the quality of remote sensing images, and bring adverse effects to the image interpretation. To remove the effect of thin clouds on images, an uneven illumination correction can be applied. In this paper, an effective uneven illumination correction algorithm is proposed to remove the effect of thin clouds and to restore the ground information of the optical remote sensing image. The imaging model of remote sensing images covered by thin clouds is analyzed. Due to the transmission attenuation, reflection, and scattering, the thin cloud cover usually increases region brightness and reduces saturation and contrast of the image. As a result, a wavelet domain enhancement is performed for the image in Hue-Saturation-Value (HSV color space. We use images with thin clouds in Wuhan area captured by QuickBird and ZiYuan-3 (ZY-3 satellites for experiments. Three traditional uneven illumination correction algorithms, i.e., multi-scale Retinex (MSR algorithm, homomorphic filtering (HF-based algorithm, and wavelet transform-based MASK (WT-MASK algorithm are performed for comparison. Five indicators, i.e., mean value, standard deviation, information entropy, average gradient, and hue deviation index (HDI are used to analyze the effect of the algorithms. The experimental results show that the proposed algorithm can effectively eliminate the influences of thin clouds and restore the real color of ground objects under thin clouds.

  4. Effect of oxygen stoichiometry in LuFe2O(4-δ) and its microstructure observed by aberration-corrected transmission electron microscopy.

    Science.gov (United States)

    Yang, H X; Tian, H F; Wang, Z; Qin, Y B; Ma, C; Li, J Q; Cheng, Z Y; Yu, R; Zhu, J

    2012-10-31

    A series of oxygen deficient LuFe(2)O(4-δ) materials have been prepared under a controlled oxygen partial-pressure atmosphere. Measurements of magnetization reveal that the increase of oxygen deficiencies could evidently depress the ferrimagnetic phase transition temperature (T(N)). In additional to the well-known charge ordering within the (11(-)0) crystal plane, a visible structural modulation with q = (0,1/4.2,7/8) commonly appears on the (100) plane in the oxygen deficient samples. An aberration-corrected transmission electron microscopy study on the oxygen deficient samples demonstrates the presence of oxygen vacancies and local structural distortion. The atomic structural features in correlation with the structural modulation, distortion of the FeO(5) polyhedron and the (001) twinning domains have been also examined. PMID:23032863

  5. Local symmetry breaking of a thin crystal structure of β-Si3N4 as revealed by spherical aberration corrected high-resolution transmission electron microscopy images.

    Science.gov (United States)

    Kim, Hwang Su; Zhang, Zaoli; Kaiser, Ute

    2012-06-01

    This report is an extension of the study for structural imaging of 5-6 nm thick β-Si(3)N(4) [0001] crystal with a spherical aberration corrected transmission electron microscope by Zhang and Kaiser [2009. Structure imaging of β-Si(3)N(4) by spherical aberration-corrected high-resolution transmission electron microscopy. Ultramicroscopy 109, 1114-1120]. In this work, a local symmetry breaking with an uneven resolution of dumbbells in the six-membered rings revealed in the reported images in the study of Zhang and Kaiser has been analyzed in detail. It is found that this local asymmetry in the image basically is not relevant to a slight mistilt of the specimen and/or a beam tilt (coma). Rather the certain variation of the tetrahedral bond length of Si-N(4) in the crystal structure is found to be responsible for the uneven resolution with a local structural variation from region to region. This characteristic of the variation is also supposed to give a distorted lattice of apparently 2°-2.5° deviations from the perfect hexagonal unit cell as observed in the reported image in the work of Zhang and Kaiser. It is discussed that this variation may prevail only in a thin specimen with a thickness ranging ~≤ 5-6 nm. At the same time, it is noted that the average of the bond length variation is close to the fixed length known in a bulk crystal of β-Si(3)N(4).

  6. A Novel Dynamic Bandwidth Allocation Algorithm with Correction-based the Multiple Traffic Prediction in EPON

    Directory of Open Access Journals (Sweden)

    Ziyi Fu

    2012-10-01

    Full Text Available According to the upstream TDM in the system of Ethernet passive optical network (EPON, this paper proposes a novel dynamic bandwidth allocation algorithm which supports the mechanism with correction-based the multiple services estimation. To improve the real-time performance of the bandwidth allocation, this algorithm forecasts the traffic of high priority services, and then pre-allocate bandwidth for various priority services is corrected according to Gaussian distribution characteristics, which will make traffic prediction closer to the real traffic. The simulation results show that proposed algorithm is better than the existing DBA algorithm. Not only can it meet the delay requirement of high priority services, but also control the delay abnormity of low priority services. In addition, with rectification scheme, it obviously improves the bandwidth utilization.

  7. Actuator Disc Model Using a Modified Rhie-Chow/SIMPLE Pressure Correction Algorithm

    DEFF Research Database (Denmark)

    Rethore, Pierre-Elouan; Sørensen, Niels

    2008-01-01

    An actuator disc model for the flow solver EllipSys (2D&3D) is proposed. It is based on a correction of the Rhie-Chow algorithm for using discreet body forces in collocated variable finite volume CFD code. It is compared with three cases where an analytical solution is known.......An actuator disc model for the flow solver EllipSys (2D&3D) is proposed. It is based on a correction of the Rhie-Chow algorithm for using discreet body forces in collocated variable finite volume CFD code. It is compared with three cases where an analytical solution is known....

  8. A new adaptive nonuniformity correction algorithm for infrared line scanner based on neural networks

    Institute of Scientific and Technical Information of China (English)

    Jing Sui; Liquan Dong; Weiqi Jin; Yayuan Zhang

    2007-01-01

    The striping pattern nonuniformity of the infrared line scanner (IRLS) severely limits the system performance. An adaptive nonuniformity correction (NUC) algorithm for IRLS using neural network is proposed.It uses a one-dimensional median filter to generate ideal output of network and can complete NUC by a single frame with a high correction level. Applications to both simulated and real infrared images show that the algorithm can obtain a satisfactory result with low complexity, no need of scene diversity or global motion between consecutive frames. It has the potential to realize real-time hardware-based applications.

  9. The generation algorithm of arbitrary polygon animation based on dynamic correction

    Directory of Open Access Journals (Sweden)

    Hou Ya Wei

    2016-01-01

    Full Text Available This paper, based on the key-frame polygon sequence, proposes a method that makes use of dynamic correction to develop continuous animation. Firstly we use quadratic Bezier curve to interpolate the corresponding sides vector of polygon sequence consecutive frame and realize the continuity of animation sequences. And then, according to Bezier curve characteristic, we conduct dynamic regulation to interpolation parameters and implement the changing smoothness. Meanwhile, we take use of Lagrange Multiplier Method to correct the polygon and close it. Finally, we provide the concrete algorithm flow and present numerical experiment results. The experiment results show that the algorithm acquires excellent effect.

  10. Comparison of Adaptive Optics and Phase-Conjugate Mirrors for Correction of Aberrations in Double-Pass Amplifiers

    Science.gov (United States)

    Jackel, Steven; Moshe, Inon; Lavi, Raphy

    2003-02-01

    Correction of birefringence-induced effects (depolarization and bipolar focusing) were achieved in double-pass amplifiers by use of a Faraday rotator between the laser rod and the retroreflecting optic. A necessary condition was ray retrace. Retrace was limited by imperfect conjugate-beam fidelity and by nonreciprocal refractive indices. We compared various retroreflectors: stimulated-Brillouin-scatter phase-conjugate mirrors (PCMs), PCMs with rod-to-PCM relay imaging (IPCM), IPCMs with astigmatism-correcting adaptive optics, and all-adaptive-optics imaging variable-radius mirrors. Results with flash-lamp-pumped, Nd:Cr:GSGG double-pass amplifiers showed the superiority of adaptive optics over nonlinear optics retroreflectors in terms of maximum average power, improved beam quality, and broader oscillator pulse duration /bandwidth operating range. Hybrid PCM-adaptive optics retroreflectors yielded intermediate power /beam-quality results.

  11. Multiprocessing and Correction Algorithm of 3D-models for Additive Manufacturing

    Science.gov (United States)

    Anamova, R. R.; Zelenov, S. V.; Kuprikov, M. U.; Ripetskiy, A. V.

    2016-07-01

    This article addresses matters related to additive manufacturing preparation. A layer-by-layer model presentation was developed on the basis of a routing method. Methods for correction of errors in the layer-by-layer model presentation were developed. A multiprocessing algorithm for forming an additive manufacturing batch file was realized.

  12. FAILURE CORRECTION OF LINEAR ARRAY ANTENNA WITH MULTIPLE NULL PLACEMENT USING CUCKOO SEARCH ALGORITHM

    Directory of Open Access Journals (Sweden)

    R. Muralidaran

    2014-03-01

    Full Text Available The influence of evolutionary algorithms enhanced its scope of getting its existence in almost every complex optimization problems. In this paper, cuckoo search algorithm, an algorithm based on the brood parasite behavior along with Levy weights has been proposed for the radiation pattern correction of a linear array of isotropic antennas with uniform spacing when failed with more than one antenna element. Even though deterioration produced by the failure of antenna elements results in various undesirable effects, consideration in this paper is given to the correction of side lobe level and null placement at two places. Various articles in the past have already shown that the idea to correct the radiation pattern is to alter the amplitude weights of the remaining unfailed elements, instead of replacing the faulty elements. This approach is made use of modifying the current excitations of unfailed elements using cuckoo search algorithm such that the resulting radiation pattern is similar to the unfailed original pattern in terms of side lobe level and null placement at two places. Examples shown in this paper demonstrate the effectiveness of this algorithm in achieving the desired objectives.

  13. Distortion correction algorithm for UAV remote sensing image based on CUDA

    International Nuclear Information System (INIS)

    In China, natural disasters are characterized by wide distribution, severe destruction and high impact range, and they cause significant property damage and casualties every year. Following a disaster, timely and accurate acquisition of geospatial information can provide an important basis for disaster assessment, emergency relief, and reconstruction. In recent years, Unmanned Aerial Vehicle (UAV) remote sensing systems have played an important role in major natural disasters, with UAVs becoming an important technique of obtaining disaster information. UAV is equipped with a non-metric digital camera with lens distortion, resulting in larger geometric deformation for acquired images, and affecting the accuracy of subsequent processing. The slow speed of the traditional CPU-based distortion correction algorithm cannot meet the requirements of disaster emergencies. Therefore, we propose a Compute Unified Device Architecture (CUDA)-based image distortion correction algorithm for UAV remote sensing, which takes advantage of the powerful parallel processing capability of the GPU, greatly improving the efficiency of distortion correction. Our experiments show that, compared with traditional CPU algorithms and regardless of image loading and saving times, the maximum acceleration ratio using our proposed algorithm reaches 58 times that using the traditional algorithm. Thus, data processing time can be reduced by one to two hours, thereby considerably improving disaster emergency response capability

  14. On the New Algorithm of Testing and Comparing Size Corrected Powers for Testing Multivariate Normality

    Directory of Open Access Journals (Sweden)

    Sima Rani Dey

    2012-04-01

    Full Text Available Parametric models are mainly based on univariate or multivariate normality assumptions. Uniformly most powerful (UMP test is not available to test multivariate normality. In such a situation, optimal test can be used. But, a very few literature is available on the size corrected power comparison of different multivariate normality tests. In this paper, we propose an algorithm to compare the size corrected powers for testing univariate or multivariate normality. The algorithm can be applied to any existing univariate and multivariate tests, which is the most attractive feature of the proposed new algorithm. We also propose a Cholesky decomposition of the variance-covariance matrix based test, which is simpler than the existing test. Our Monte Carlo simulation study indicates that our proposed and existing tests perform equally in terms of power properties. Keywords— Cholesky decomposition, UMP test, Optimal test, Monte Carlo.

  15. A FORTRAN algorithm for correcting normal resistivity logs for borehole diameter and mud resistivity

    Science.gov (United States)

    Scott, James Henry

    1978-01-01

    The FORTRAN algorithm described in this report was developed for applying corrections to normal resistivity logs of any electrode spacing for the effects of drilling mud of known resistivity in boreholes of variable diameter. The corrections are based on Schlumberger departure curves that are applicable to normal logs made with a standard Schlumberger electric logging probe with an electrode diameter of 8.5 cm (3.35 in). The FORTRAN algorithm has been generalized to accommodate logs made with other probes with different electrode diameters. Two simplifying assumptions used by Schlumberger in developing the departure curves also apply to the algorithm: (1) bed thickness is assumed to be infinite (at least 10 times larger than the electrode spacing), and (2) invasion of drilling mud into the formation is assumed to be negligible. * The use of a trade name does not necessarily constitute endorsement by the U.S. Geological Survey.

  16. Atomic-resolution studies of In2O3-ZnO compounds on aberration-corrected electron microscopes

    International Nuclear Information System (INIS)

    In this work, the characteristic inversion domain microstructures of In2O3(ZnO)m (m=30) compounds were investigated by TEM methods. At bright-atom contrast condition, atomically resolved HR-TEM images of In2O3(ZnO)30 were successfully acquired in [1 anti 100] zone axis of ZnO, with projected metal columns of ∝1.6 A well resolved. From contrast maxima in the TEM images, local lattice distortions at the pyramidal inversion domain boundaries were observed for the first time. Lattice displacements and the strain field in two-dimensions were visualized and measured using the 'DALI' algorithm. Atomically resolved single shot and focal series images of In2O3(ZnO)30 were achieved in both zone axes of ZnO, [1 anti 100] and [2 anti 1 anti 10], respectively. The electron waves at the exit-plane were successfully reconstructed using the software package 'TrueImage'. Finally, a three dimensional atomic structure model for the pyramidal IDB was proposed, with an In distribution of 10%, 20%, 40%, 20% and 10% of In contents over 5 atom columns along basal planes, respectively. Through a detailed structural study of In2O3(ZnO)m compounds by using phase-contrast and Z-contrast imaging at atomic resolution, In3+ atoms are determined with trigonal bi-pyramidal co-ordination and are distributed at the pyramidal IDBs. (orig.)

  17. Aberration correction in double-pass amplifiers through the use of phase-conjugate mirrors and/or adaptive optics

    Science.gov (United States)

    Jackel, Steven M.; Moshe, Inon; Lavi, Raphael

    2001-04-01

    Corrrection of birefringence induced effects (depolarization and bipolar focusing) was achieved in double-pass amplifiers using a Faraday rotator placed between the laser rod and the retroreflecting optic. A necessary condition was that each ray in the beam retraced its path through the amplifying medium. Retrace was limited by imperfect conjugate-beam fidelity and by nonreciprocal double-pass indices of refraction. We compare various retroreflectors: stimulated Brillouin scatter phase-conjugate-mirrors (PCMs), PCMs with relay lenses to image the rod principal plane onto the PCM entrance aperture (IPCMs), IPCMs with external, adaptively-adjusted, astigmatism-correcting cylindrical doublets, and all adaptive optics imaging variable-radius-mirrors (IVRMs). Results with flashlamp pumped, Nd:Cr:GSGG double-pass amplifiers show that average output power increased fivefold with a Faraday rotator plus complete nonlinear optics retroreflector package (IPCM+cylindrical zoom), and that this represents an 80% increase over the power achieved using just a PCM. Far better results are, however, achieved with an IVRM.

  18. An improved TES algorithm based on the corrected ALPHA difference spectrum

    Institute of Scientific and Technical Information of China (English)

    TANG ShiHao; LI XiaoWen; WANG JinDi; ZHU QiJiang; ZHANG LiHua

    2007-01-01

    Different from visible signals, thermal infrared radiances depend on both temperature and emissivity. It is a key problem for us to separate temperature and emissivity in thermal infrared remote sensing research. Another difficulty encountered in the retrieval of surface temperature is the correction of downwelling sky irradiance, because it is closely related to surface emissivity. When emissivity is unknown, the downwelling sky irradiance is difficult to be removed. In this paper, we introduce a correction term of downwelling sky irradiance developed by Li and Becker into Wien's approximation, to derive an improved ALPHA difference spectrum which is independent of temperature, and furthermore develop a correction term to remove the error of Wien's approximation. Under the support of the above work, attractive features of Alpha derived emissivity method and ASTER TES algorithm are combined together to acquire a new Improved TES algorithm based on Corrected ALPHA Difference Spectrum (ICADS TES). Because a multi-band inversion technique is applied, and the operations of band ratios and differences are included in the algorithm, it can partly remove the influence of atmosphere and noises. Numerical simulation experiments show that for various combinations of atmosphere, land covers and surface temperatures, the algorithm is applicable and stable. Its accuracy for temperature is 0―1.5 K, and that for emissivity is 0―0.015. Compared with current TES algorithms, our method has clear physical meaning, is easy to be implemented, and is applicable for a wide temperature range and surface types. The results are not influenced by the directional characteristic of emissivity. Because ICADS TES does not need the support of a priori information of surface types, it is also not influenced by the accuracy of classification and the problem of mixture pixels. Compared with our former TES algorithm based on corrected Alpha difference spectra (CADS TES), the new algorithm takes

  19. Assessing heterogeneity correction algorithms using the Radiological Physics Center's anthropomorphic thorax phantom

    International Nuclear Information System (INIS)

    The Radiological Physics Center (RPC) was established as a resource in radiation dosimetry and physics for cooperative clinical trial groups and radiotherapy facilities that deliver radiation treatments to patients entered onto cooperative group protocols. The RPC's primary responsibility is to assure NCI and the cooperative groups that the participating institutions deliver radiation treatments that are clinically comparable to those delivered by other institutions in the cooperative groups. One of the remote audit techniques used by the RPC to assure NCI is to credential institutions using its anthropomorphic phantoms, i.e. an end to end test from imaging to planning to final dose delivery as if the phantom were an actual patient. With the recent the implementation of several lung protocols requiring heterogeneity corrected target doses, the RPC, through its credentialing activities have evaluated numerous heterogeneity correction algorithms as used in various treatment planning systems. These systems include Elekta Pinnacle superposition convolution (SC) (adaptive convolve and collapsed cone) algorithms, Varian Eclipse pencil beam (PB) and AAA algorithms, TomoTherapy planning station SC, Accuray Multiplan PB and Monte Carlo (MC) algorithms, Nomos Corvus PB, CMS XiO SC, BrainLab PB and Elekta PrecisePlan Clarkson algorithm

  20. Some correct error-driven versions of the Constraint Demotion algorithm

    OpenAIRE

    Boersma, P.

    2009-01-01

    This article shows that Error-Driven Constraint Demotion (EDCD), an error-driven learning algorithm proposed by Tesar (1995) for Prince and Smolensky’s (1993/2004) version of Optimality Theory, can fail to converge to a correct totally ranked hierarchy of constraints, unlike the earlier non-error-driven learning algorithms proposed by Tesar and Smolensky (1993). The cause of the problem is found in Tesar’s use of "mark-pooling ties," indicating that EDCD can be repaired by assuming Anttila’s ...

  1. Pulse filtering and correction for CZT detectors using simple digital algorithms based on the wavelet transform

    International Nuclear Information System (INIS)

    The authors report an approach to double gaussian filtering used in classical works as dual parameter pulse processing. This technique has been implemented by creating a bank of gaussian-like digital filters based on wavelet transforms. A simple method to correct for the charge loss inherent to room temperature semiconductor gamma detectors has been developed. This method is based on multi-resolution signal analysis. Results are reported from tests of these algorithms on commercial CZT detectors and two trapped hole charge correction levels are compared. Finally, the advantages and limitations of this new approach to detector pulse processing are discussed

  2. Migration of Single Iridium Atoms and Tri-iridium Clusters on MgO Surfaces. Aberration-Corrected STEM Imaging and ab-initio Calculations

    Energy Technology Data Exchange (ETDEWEB)

    Han, Chang W. [Purdue Univ., West Lafayette, IN (United States); Iddir, Hakim [Argonne National Lab. (ANL), Argonne, IL (United States); Uzun, Alper [Koc Univ., Instanbul (Turkey); Curtiss, Larry A. [Argonne National Lab. (ANL), Argonne, IL (United States); Browning, Nigel D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gates, Bruce C. [Univ. of California, Davis, CA (United States); Ortalan, Volkan [Purdue Univ., West Lafayette, IN (United States)

    2015-11-06

    To address the challenge of fast, direct atomic-scale visualization of the diffusion of atoms and clusters on surfaces, we used aberration-corrected scanning transmission electron microscopy (STEM) with high scan speeds (as little as ~0.1 s per frame) to visualize the diffusion of (1) a heavy atom (Ir) on the surface of a support consisting of light atoms, MgO(100), and (2) an Ir3 cluster on MgO(110). Sequential Z-contrast images elucidate the diffusion mechanisms, including the hopping of Ir1 and the rotational migration of Ir3 as two Ir atoms remain anchored to the surface. Density functional theory (DFT) calculations provided estimates of the diffusion energy barriers and binding energies of the iridium species to the surfaces. The results show how the combination of fast-scan STEM and DFT calculations allow real-time visualization and fundamental understanding of surface diffusion phenomena pertaining to supported catalysts and other materials.

  3. Ground target localization algorithm for semi-active laser terminal correction projectile

    Directory of Open Access Journals (Sweden)

    Xing-long Li

    2016-06-01

    Full Text Available A target localization algorithm, which uses the measurement information from onboard GPS and onboard laser detector to acquire the target position, is proposed to obtain the accurate position of ground target in real time in the trajectory correction process of semi-active laser terminal correction projectile. A target localization model is established according to projectile position, attitude and line-of-sight angle. The effects of measurement errors of projectile position, attitude and line-of-sight angle on localization accuracy at different quadrant elevation angles are analyzed through Monte-Carlo simulation. The simulation results show that the measurement error of line-of-sight angle has the largest influence on the localization accuracy. The localization accuracy decreases with the increase in quadrant elevation angle. However, the maximum localization accuracy is less than 7 m. The proposed algorithm meets the accuracy and real-time requirements of target localization.

  4. A simplified algorithm for correcting both errors and erasures of R-S codes

    Science.gov (United States)

    Reed, I. S.; Truong, T. K.

    1978-01-01

    Using the finite field transform and continued fractions, a simplified algorithm for decoding Reed-Solomon (R-S) codes is developed to correct erasures caused by other codes as well as errors over the finite field GF (q(m), where q is a prime and m is an integer. Such an R-S decoder can be faster and simpler than a decoder that uses more conventional methods.

  5. Simplified algorithm for correcting both errors and erasures of Reed-Solomon codes

    Science.gov (United States)

    Reed, I. S.; Truong, T. K.; Miller, R. L.

    1979-01-01

    Using a finite-field transform, a simplified algorithm for decoding Reed-Solomon codes is developed to correct erasures as well as errors over the finite-field GF(q to the m power), where q is a prime and m is an integer. If the finite-field transform is a fast transform, this decoder can be faster and simpler than a decoder that uses more conventional methods.

  6. Evaluation of two Vaisala RS92 radiosonde solar radiative dry bias correction algorithms

    OpenAIRE

    Dzambo, Andrew M.; Turner, David D.; Mlawer, Eli J.

    2016-01-01

    Solar heating of the relative humidity (RH) probe on Vaisala RS92 radiosondes results in a large dry bias in the upper troposphere. Two different algorithms (Miloshevich et al., 2009, MILO hereafter; and Wang et al., 2013, WANG hereafter) have been designed to account for this solar radiative dry bias (SRDB). These corrections are markedly different with MILO adding up to 40 % more moisture to the original radiosonde profile than WANG; however, the impact of the two algo...

  7. Evaluation of two Vaisala RS92 radiosonde solar radiative dry bias correction algorithms

    OpenAIRE

    A. M. Dzambo; D. D. Turner; E. J. Mlawer

    2015-01-01

    Solar heating of the relative humidity (RH) probe on Vaisala RS92 radiosondes results in a large dry bias in the upper troposphere. Two different algorithms (Miloshevich et al., 2009, MILO hereafter; and Wang et al., 2013, WANG hereafter) have been designed to account for this solar radiative dry bias (SRDB). These corrections are markedly different with MILO adding up to 40 % more moisture to the original radiosonde profile than WANG; however, the impact of the two algori...

  8. [A quickly atmospheric correction method for HJ-1 CCD with deep blue algorithm].

    Science.gov (United States)

    Wang, Zhong-Ting; Wang, Hong-Mei; Li, Qing; Zhao, Shao-Hua; Li, Shen-Shen; Chen, Liang-Fu

    2014-03-01

    In the present, for the characteristic of HJ-1 CCD camera, after receiving aerosol optical depth (AOD) from deep blue algorithm which was developed by Hsu et al. assisted by MODerate-resolution imaging spectroradiometer (MODIS) surface reflectance database, bidirectional reflectance distribution function (BRDF) correction with Kernel-Driven Model, and the calculation of viewing geometry with auxiliary data, a new atmospheric correction method of HJ-1 CCD was developed which can be used over vegetation, soil and so on. And, when the CCD data is processed to correct atmospheric influence, with look up table (LUT) and bilinear interpolation, atmospheric correction of HJ-1 CCD is completed quickly by grid calculation of atmospheric parameters and matrix operations of interface define language (IDL). The experiment over China North Plain on July 3rd, 2012 shows that by our method, the atmospheric influence was corrected well and quickly (one CCD image of 1 GB can be corrected in eight minutes), and the reflectance after correction over vegetation and soil was close to the spectrum of vegetation and soil. The comparison with MODIS reflectance product shows that for the advantage of high resolution, the corrected reflectance image of HJ-1 is finer than that of MODIS, and the correlation coefficient of the reflectance over typical surface is greater than 0.9. Error analysis shows that the recognition error of aerosol type leads to 0. 05 absolute error of surface reflectance in near infrared band, which is larger than that in visual bands, and the 0. 02 error of reflectance database leads to 0.01 absolute error of surface reflectance of atmospheric correction in green and red bands. PMID:25208402

  9. An improved TES algorithm based on the corrected ALPHA difference spectrum

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Different from visible signals, thermal infrared radiances depend on both temperature and emissivity. It is a key problem for us to separate temperature and emissivity in thermal infrared remote sensing re- search. Another difficulty encountered in the retrieval of surface temperature is the correction of downwelling sky irradiance, because it is closely related to surface emissivity. When emissivity is un- known, the downwelling sky irradiance is difficult to be removed. In this paper, we introduce a correc- tion term of downwelling sky irradiance developed by Li and Becker into Wien’s approximation, to de- rive an improved ALPHA difference spectrum which is independent of temperature, and furthermore develop a correction term to remove the error of Wien’s approximation. Under the support of the above work, attractive features of Alpha derived emissivity method and ASTER TES algorithm are combined together to acquire a new Improved TES algorithm based on Corrected ALPHA Difference Spectrum (ICADS TES). Because a multi-band inversion technique is applied, and the operations of band ratios and differences are included in the algorithm, it can partly remove the influence of atmosphere and noises. Numerical simulation experiments show that for various combinations of atmosphere, land covers and surface temperatures, the algorithm is applicable and stable. Its accuracy for temperature is 0―1.5 K, and that for emissivity is 0―0.015. Compared with current TES algorithms, our method has clear physical meaning, is easy to be implemented, and is applicable for a wide temperature range and surface types. The results are not influenced by the directional characteristic of emissivity. Because ICADS TES does not need the support of a priori information of surface types, it is also not influenced by the accuracy of classification and the problem of mixture pixels. Compared with our former TES algorithm based on corrected Alpha difference spectra (CADS TES), the new

  10. SKIP TRIE MATCHING: A GREEDY ALGORITHM FOR REAL-TIME OCR ERROR CORRECTION ON SMARTPHONES

    Directory of Open Access Journals (Sweden)

    Vladimir Kulyukin

    2014-03-01

    Full Text Available Proactive nutrition management is considered by many nutritionists and dieticians as a key factor in reducing diabetes, cancer, and other illnesses caused by mismanaged diets. As more individuals manage their daily activities with smartphones, they start using their smartphones as diet management tools. Unfortunately, while there are many visionbased mobile applications to process barcodes, especially aligned ones, there is a relative dearth of vision-based applications for extracting useful nutrition information items such as nutrition facts, caloric contents, and ingredients. In this article, we present a greedy algorithm, called Skip Trie Matching (STM, for real time optical character recognition (OCR output error correction on smartphones. The STM algorithm uses a dictionary of strings stored in a trie data structure to correct OCR errors by skipping misrecognized characters while driving down several paths in the trie. The number of skipped characters is referred to as the skip distance. The algorithm’s worst-case performance is n , where n is the length of the input string to spellcheck. The algorithm’s performance is compared with Apache Lucene’s spell checker [1], a state of the art spell checker where spell checking can be done with the n-gram matching [2] or the Levenshtein edit distance (LED [3]. The input data for comparison tests are text strings produced by the Tesserract OCR engine [4] on text image segments of nutrition data automatically extracted by an Android 2.3.6 smartphone application from real-time video streams of grocery product packages. The evaluation results indicate that, while the STM algorithm is greedy in that it does not find all possible corrections of a misspelled word, it gives higher recalls than Lucene’s n-gram matching or LED. The average run time of the STM algorithm is also lower than Lucene’s implementations of both algorithms.

  11. A new algorithm and results of ionospheric delay correction for satellite-based augmentation system

    Science.gov (United States)

    Huang, Z.; Yuan, H.

    Ionospheric delay resulted from radio signals traveling ionosphere is the largest source of errors for single-frequency users of the Global Positioning System GPS In order to improve users position accuracy augmentation systems based on satellite have been developed to provide accurate calibration since the nineties A famous one is Wide Area Augmentation System WAAS which is aimed to the efficiency of navigation over the conterminous United States and has been operating successfully so far The main idea of ionospheric correction algorithm for WAAS is to establish ionospheric grid model i e ionosphere is discretized into a set of regularly-spaced intervals in latitude and longitude at an altitude of 350km above the earth surface The users calculate their pseudoranges by interpolating estimates of vertical ionospheric delay modeled at ionospheric grid points The Chinese crust deformation monitoring network has been established since the eighties and now it is in good operation with 25 permanent GPS stations which provide feasibility to construct similar satellite-based augmentation system SBAS in China For the west region of China the distribution of stations is relatively sparse not to ensure sufficient data If we follow the ionospheric grid correction algorithm some grid points can t obtain their estimate and lost availability Consequently ionospheric correction measurement on the users situated in that region is inestimable which constitute a fatal threat to navigation users In this paper we presented a new algorithm that

  12. Minimizing light absorption measurement artifacts of the Aethalometer: evaluation of five correction algorithms

    Science.gov (United States)

    Collaud Coen, M.; Weingartner, E.; Apituley, A.; Ceburnis, D.; Fierz-Schmidhauser, R.; Flentje, H.; Henzing, J. S.; Jennings, S. G.; Moerman, M.; Petzold, A.; Schmid, O.; Baltensperger, U.

    2010-04-01

    The aerosol light absorption coefficient is an essential parameter involved in atmospheric radiation budget calculations. The Aethalometer (AE) has the great advantage of measuring the aerosol light absorption coefficient at several wavelengths, but the derived absorption coefficients are systematically too high when compared to reference methods. Up to now, four different correction algorithms of the AE absorption coefficients have been proposed by several authors. A new correction scheme based on these previously published methods has been developed, which accounts for the optical properties of the aerosol particles embedded in the filter. All the corrections have been tested on six datasets representing different aerosol types and loadings and include multi-wavelength AE and white-light AE. All the corrections have also been evaluated through comparison with a Multi-Angle Absorption Photometer (MAAP) for four datasets lasting between 6 months and five years. The modification of the wavelength dependence by the different corrections is analyzed in detail. The performances and the limits of all AE corrections are determined and recommendations are given.

  13. Minimizing light absorption measurement artifacts of the Aethalometer: evaluation of five correction algorithms

    Directory of Open Access Journals (Sweden)

    M. Collaud Coen

    2010-04-01

    Full Text Available The aerosol light absorption coefficient is an essential parameter involved in atmospheric radiation budget calculations. The Aethalometer (AE has the great advantage of measuring the aerosol light absorption coefficient at several wavelengths, but the derived absorption coefficients are systematically too high when compared to reference methods. Up to now, four different correction algorithms of the AE absorption coefficients have been proposed by several authors. A new correction scheme based on these previously published methods has been developed, which accounts for the optical properties of the aerosol particles embedded in the filter. All the corrections have been tested on six datasets representing different aerosol types and loadings and include multi-wavelength AE and white-light AE. All the corrections have also been evaluated through comparison with a Multi-Angle Absorption Photometer (MAAP for four datasets lasting between 6 months and five years. The modification of the wavelength dependence by the different corrections is analyzed in detail. The performances and the limits of all AE corrections are determined and recommendations are given.

  14. Minimizing light absorption measurement artifacts of the Aethalometer: evaluation of five correction algorithms

    Directory of Open Access Journals (Sweden)

    M. Collaud Coen

    2009-07-01

    Full Text Available The aerosol light absorption coefficient is an essential parameter involved in atmospheric radiation budget calculations. The Aethalometer (AE has the great advantage of measuring the aerosol light absorption coefficient at several wavelengths, but the derived absorption coefficients are systematically too high when compared to reference methods. Up to now, four different correction algorithms of the AE absorption coefficients have been proposed by several authors. A new correction scheme based on these previously published methods has been developed, which accounts for the optical properties of the aerosol particles embedded in the filter. All the corrections have been tested on six datasets representing different aerosol types and loadings and include multi-wavelength AE and white-light AE. All the corrections have also been evaluated through comparison with a Multi-Angle Absorption Photometer (MAAP for four datasets lasting between 6 months and five years. The modification of the wavelength dependence by the different corrections is analyzed in detail. The performances and the limits of all AE corrections are determined and recommendations are given.

  15. Corrected explicit-implicit domain decomposition algorithms for two-dimensional semilinear parabolic equations

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Corrected explicit-implicit domain decomposition(CEIDD) algorithms are studied for parallel approximation of semilinear parabolic problems on distributed memory processors. It is natural to divide the spatial domain into some smaller parallel strips and cells using the simplest straightline interface(SI) . By using the Leray-Schauder fixed-point theorem and the discrete energy method,it is shown that the resulting CEIDD-SI algorithm is uniquely solvable,unconditionally stable and convergent. The CEIDD-SI method always suffers from the globalization of data communication when interior boundaries cross into each other inside the domain. To overcome this disadvantage,a composite interface(CI) that consists of straight segments and zigzag fractions is suggested. The corresponding CEIDD-CI algorithm is proven to be solvable,stable and convergent. Numerical experiments are presented to support the theoretical results.

  16. Corrected explicit-implicit domain decomposition algorithms for two-dimensional semilinear parabolic equations

    Institute of Scientific and Technical Information of China (English)

    LIAO HongLin; SHI HanSheng; SUN ZhiZhong

    2009-01-01

    Corrected explicit-implicit domain decomposition (CEIDD) algorithms are studied for parallel approximation of semilinear parabolic problems on distributed memory processors. It is natural to divide the spatial domain into some smaller parallel strips and cells using the simplest straight-line interface (SI). By using the Leray-Schauder fixed-point theorem and the discrete energy method, it is shown that the resulting CEIDD-SI algorithm is uniquely solvable, unconditionally stable and convergent. The CEIDD-SI method always suffers from the globalization of data communication when interior boundaries cross into each other inside the domain. To overcome this disadvantage, a composite interface (CI) that consists of straight segments and zigzag fractions is suggested. The corresponding CEIDD-CI algorithm is proven to be solvable, stable and convergent. Numerical experiments are presented to support the theoretical results.

  17. An Improved Scene-based Nonuniformity Correction Algorithm for Infrared Focal Plane Arrays Using Neural Networks

    Institute of Scientific and Technical Information of China (English)

    SUI Jing; JIN Wei-qi; DONG Li-quan; WANG Xia; GUO Hong

    2006-01-01

    The improved scene-based adaptive nonuniformity correction (NUC) algorithms using a neural network (NNT) approach for infrared image sequences are presented and analyzed. The retina-like neural networks using steepest descent model was the first proposed infrared focal plane arrays (IRFPA) nonuniformity compensation method, which can perform parameter estimation of the sensors over time on a frame by frame basis. To increase the strength and the robustness of the NNT algorithm and to avoid the presence of ghosting artifacts, some optimization techniques, including momentum term,regularization factor and adaptive learning rate, were executed in the parameter learning process. In this paper, the local median filtering result of Xij ( n ) is proposed as an alternative value of desired network output of neuron Xij ( n ), denoted as Tij ( n ), which is the local spatial average of Xij ( n ) in traditional NNT methods. Noticeably, the NUC algorithm is inter-frame adaptive in nature and does not rely on any statistical assumptions on the scene data in the image sequence.Applications of this algorithm to the simulated video sequences and real infrared data taken with PV320 show that the correction results of image sequence are better than that of using original NNT approach, especially for the short-time image sequences (several hundred frames) subjected to the dense impulse noises with a number of dead or saturated pixels.

  18. Correcting encoder interpolation error on the Green Bank Telescope using an iterative model based identification algorithm

    Science.gov (United States)

    Franke, Timothy; Weadon, Tim; Ford, John; Garcia-Sanz, Mario

    2015-10-01

    Various forms of measurement errors limit telescope tracking performance in practice. A new method for identifying the correcting coefficients for encoder interpolation error is developed. The algorithm corrects the encoder measurement by identifying a harmonic model of the system and using that model to compute the necessary correction parameters. The approach improves upon others by explicitly modeling the unknown dynamics of the structure and controller and by not requiring a separate system identification to be performed. Experience gained from pin-pointing the source of encoder error on the Green Bank Radio Telescope (GBT) is presented. Several tell-tale indicators of encoder error are discussed. Experimental data from the telescope, tested with two different encoders, are presented. Demonstration of the identification methodology on the GBT as well as details of its implementation are discussed. A root mean square tracking error reduction from 0.68 arc seconds to 0.21 arc sec was achieved by changing encoders and was further reduced to 0.10 arc sec with the calibration algorithm. In particular, the ubiquity of this error source is shown and how, by careful correction, it is possible to go beyond the advertised accuracy of an encoder.

  19. Alignment algorithms and per-particle CTF correction for single particle cryo-electron tomography.

    Science.gov (United States)

    Galaz-Montoya, Jesús G; Hecksel, Corey W; Baldwin, Philip R; Wang, Eryu; Weaver, Scott C; Schmid, Michael F; Ludtke, Steven J; Chiu, Wah

    2016-06-01

    Single particle cryo-electron tomography (cryoSPT) extracts features from cryo-electron tomograms, followed by 3D classification, alignment and averaging to generate improved 3D density maps of such features. Robust methods to correct for the contrast transfer function (CTF) of the electron microscope are necessary for cryoSPT to reach its resolution potential. Many factors can make CTF correction for cryoSPT challenging, such as lack of eucentricity of the specimen stage, inherent low dose per image, specimen charging, beam-induced specimen motions, and defocus gradients resulting both from specimen tilting and from unpredictable ice thickness variations. Current CTF correction methods for cryoET make at least one of the following assumptions: that the defocus at the center of the image is the same across the images of a tiltseries, that the particles all lie at the same Z-height in the embedding ice, and/or that the specimen, the cryo-electron microscopy (cryoEM) grid and/or the carbon support are flat. These experimental conditions are not always met. We have developed a CTF correction algorithm for cryoSPT without making any of the aforementioned assumptions. We also introduce speed and accuracy improvements and a higher degree of automation to the subtomogram averaging algorithms available in EMAN2. Using motion-corrected images of isolated virus particles as a benchmark specimen, recorded with a DE20 direct detection camera, we show that our CTF correction and subtomogram alignment routines can yield subtomogram averages close to 4/5 Nyquist frequency of the detector under our experimental conditions. PMID:27016284

  20. A dispersion and pulse width correction algorithm for the pulsed wire method

    Energy Technology Data Exchange (ETDEWEB)

    Arbelaez, D., E-mail: darbelaez@lbl.gov [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Wilks, T. [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); University of California, Berkeley, CA 94720 (United States); Madur, A.; Prestemon, S.; Marks, S.; Schlueter, R. [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States)

    2013-07-11

    The pulsed wire technique is an attractive option for the measurement of undulators where the measurement access is restricted due to, for example, narrow undulator gaps or cryogenic environments in the case of superconducting undulators. Using the pulsed wire technique, direct measurements of the first and second integrals of the magnetic field can be obtained. However, one of the main limitations of this technique is the error introduced by dispersive wave motion, due to the finite flexural rigidity of the wire. For the measurement of the first integral of the magnetic field, an error is also introduced by the use of a current pulse with finite pulse width. In this paper, a general solution is presented for dispersive wave motion in pulsed wire measurements. A method for the measurement of the dispersive wave speed is presented and demonstrated through experimental examples. An algorithm is derived which corrects the dispersion and finite pulse-width errors in the measurement of first magnetic field integrals and the dispersion error in the measurement of second magnetic field integrals. The effectiveness of the correction algorithms is demonstrated through experimental measurements, and the results are compared with Hall probe measurements on a short undulator. -- Highlights: ► We derive the equations that describe dispersive motion in a pulsed wire magnetic measurement. ► We develop algorithms that can be used to correct measurement errors that are due to dispersive and finite pulse width effects. ► Excellent agreement is found between the corrected pulsed wire results and Hall probe measurements on a short undulator.

  1. Study on fitness functions of genetic algorithm for dynamically correcting nuclide atmospheric diffusion model

    International Nuclear Information System (INIS)

    Background: In radioactive nuclides atmospheric diffusion models, the empirical dispersion coefficients were deduced under certain experiment conditions, whose difference with nuclear accident conditions is a source of deviation. A better estimation of the radioactive nuclide's actual dispersion process could be done by correcting dispersion coefficients with observation data, and Genetic Algorithm (GA) is an appropriate method for this correction procedure. Purpose: This study is to analyze the fitness functions' influence on the correction procedure and the forecast ability of diffusion model. Methods: GA, coupled with Lagrange dispersion model, was used in a numerical simulation to compare 4 fitness functions' impact on the correction result. Results: In the numerical simulation, the fitness function with observation deviation taken into consideration stands out when significant deviation exists in the observed data. After performing the correction procedure on the Kincaid experiment data, a significant boost was observed in the diffusion model's forecast ability. Conclusion: As the result shows, in order to improve dispersion models' forecast ability using GA, observation data should be given different weight in the fitness function corresponding to their error. (authors)

  2. A real-time misalignment correction algorithm for stereoscopic 3D cameras

    Science.gov (United States)

    Pekkucuksen, Ibrahim E.; Batur, Aziz Umit; Zhang, Buyue

    2012-03-01

    Camera calibration is an important problem for stereo 3-D cameras since the misalignment between the two views can lead to vertical disparities that significantly degrade 3-D viewing quality. Offline calibration during manufacturing is not always an option especially for mass produced cameras due to cost. In addition, even if one-time calibration is performed during manufacturing, its accuracy cannot be maintained indefinitely because environmental factors can lead to changes in camera hardware. In this paper, we propose a real-time stereo calibration solution that runs inside a consumer camera and continuously estimates and corrects for the misalignment between the stereo cameras. Our algorithm works by processing images of natural scenes and does not require the use of special calibration charts. The algorithm first estimates the disparity in horizontal and vertical directions between the corresponding blocks from stereo images. Then, this initial estimate is refined with two dimensional search using smaller sub-blocks. The displacement data and block coordinates are fed to a modified affine transformation model and outliers are discarded to keep the modeling error low. Finally, the estimated affine parameters are split by half and misalignment correction is applied to each view accordingly. The proposed algorithm significantly reduces the misalignment between stereo frames and enables a more comfortable 3-D viewing experience.

  3. Applications of an AMSR-E RFI Detection and Correction Algorithm in 1-DVAR over Land

    Institute of Scientific and Technical Information of China (English)

    吴莹; 翁富忠

    2014-01-01

    Land retrievals using passive microwave radiometers are sensitive to small fluctuations in land brightness temperatures. As such, the radio-frequency interference (RFI) signals emanating from man-made microwave radiation transmitters can result in large errors in land retrievals. RFI in C-and X-band channels can con-taminate remotely sensed measurements, as experienced with the Advanced Microwave Scanning Radiometer (AMSR-E) and the WindSat sensor. In this work, applications of an RFI detection and correction algorithm in retrieving a comprehensive suite of geophysical parameters from AMSR-E measurements using the one-dimensional variational retrieval (1-DVAR) method are described. The results indicate that the values of retrieved parameters, such as land skin temperature (LST), over these areas contaminated by RFI are much higher than those from the global data assimilation system (GDAS) products. The results also indicate that the differences between new retrievals and GDAS products are decreased evidently through taking into account the RFI correction algorithm. In addition, the convergence metric (χ2) of 1-DVAR is found to be a new method for identifying regions where land retrievals are affected by RFI. For example, in those regions with much stronger RFI, such as Europe and Japan, χ2 of 1-DVAR is so large that convergence cannot be reached and retrieval results may not be reliable or cannot be obtained. Furthermore,χ2 also decreases with the RFI-corrected algorithm for those regions with moderate or weak RFI. The results of RFI detected byχ2 are almost consistent with those identified by the spectral difference method.

  4. A passive synthetic aperture phase correction algorithm for the asymmetric twin-line array sonar

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A passive synthetic aperture based on phase correction algorithm for solving the port-starboard discrimination problem in the non-aligned towed twin-line array sonar, is described. This method creates a virtual array through applying the estimated phase correction into one array of twin-line arrays. Because the synthetic virtual array is aligned with the other array in twin-line arrays, the right port-starboard discriminated results can be obtained by array processing based on the new synthetic twin-line array. The effect of proposed method has been shown by simulated and sea-trials results in towed twin-line array sonar. With low extra computational loads, the proposed method is easy to apply to the practice.

  5. Parallel Implementation of Bias Field Correction Fuzzy C-Means Algorithm for Image Segmentation

    Directory of Open Access Journals (Sweden)

    Nouredine AITALI

    2016-03-01

    Full Text Available Image segmentation in the medical field is one of the most important phases to diseases diagnosis. The bias field estimation algorithm is the most interesting techniques to correct the in-homogeneity intensity artifact on the image. However, the use of such technique requires a powerful processing and quite expensive for big size as medical images. Hence the idea of parallelism becomes increasingly required. Several researchers have followed this path mainly in the bioinformatics field where they have suggested different algorithms implementations. In this paper, a novel Single Instruction Multiple Data (SIMD architecture for bias field estimation and image segmentation algorithm is proposed. In order to accelerate compute-intensive portions of the sequential implementation, we have implemented this algorithm on three different graphics processing units (GPU cards named GT740m, GTX760 and GTX580 respectively, using Compute Unified Device Architecture (CUDA software programming tool. Numerical obtained results for the computation speed up, allowed us to conclude on the suitable GPU architecture for this kind of applications and closest ones.

  6. Algorithm for Atmospheric and Glint Corrections of Satellite Measurements of Ocean Pigment

    Science.gov (United States)

    Fraser, Robert S.; Mattoo, Shana; Yeh, Eueng-Nan; McClain, C. R.

    1997-01-01

    An algorithm is developed to correct satellite measurements of ocean color for atmospheric and surface reflection effects. The algorithm depends on taking the difference between measured and tabulated radiances for deriving water-leaving radiances. 'ne tabulated radiances are related to the measured radiance where the water-leaving radiance is negligible (670 nm). The tabulated radiances are calculated for rough surface reflection, polarization of the scattered light, and multiple scattering. The accuracy of the tables is discussed. The method is validated by simulating the effect of different wind speeds than that for which the lookup table is calculated, and aerosol models different from the maritime model for which the table is computed. The derived water-leaving radiances are accurate enough to compute the pigment concentration with an error of less than q 15% for wind speeds of 6 and 10 m/s and an urban atmosphere with aerosol optical thickness of 0.20 at lambda 443 nm and decreasing to 0.10 at lambda 670 nm. The pigment accuracy is less for wind speeds less than 6 m/s and is about 30% for a model with aeolian dust. On the other hand, in a preliminary comparison with coastal zone color scanner (CZCS) measurements this algorithm and the CZCS operational algorithm produced values of pigment concentration in one image that agreed closely.

  7. Efficient object scatter correction algorithm for third and fourth generation CT scanners

    Energy Technology Data Exchange (ETDEWEB)

    Ohnesorge, B.; Flohr, T.; Klingenbeck-Regn, K. [Siemens Medical Engineering, Dept. CTC 2, Forchheim (Germany)

    1999-04-01

    X-ray photons which are scattered inside the object slice and reach the detector array increase the detected signal and produce image artifacts as ``cupping`` effects in large objects and dark bands between regions of high attenuation. The artifact amplitudes increase with scanned volume or slice width. Object scatter can be reduced in third generation computed tomography (CT) geometry by collimating the detector elements. However, a correction can still improve image quality. For fourth generation CT geometry, only poor anti-scatter collimation is possible and a numeric correction is necessary. This paper presents a correction algorithm which can be parameterized for third and fourth generation CT geometry. The method requires low computational effort and allows flexible application to different body regions by simple parameter adjustments. The object scatter intensity which is subtracted from the measured signal is calculated with convolution of the weighted and windowed projection data with a spatially invariant ``scatter convolution function``. The scatter convolution function is approximated for the desired scanner geometry from pencil beam simulations and measurements using coherent and incoherent differential scatter cross section data. Several examples of phantom and medical objects scanned with third and fourth generation CT systems are discussed. In third generation scanners, scatter artifacts are effectively corrected. For fourth generation geometry with poor anti-scatter collimation, object scatter artifacts are strongly reduced. (orig.) With 7 figs., 1 tab., 8 refs.

  8. Parallel algorithms of relative radiometric correction for images of TH-1 satellite

    Science.gov (United States)

    Wang, Xiang; Zhang, Tingtao; Cheng, Jiasheng; Yang, Tao

    2014-05-01

    The first generation of transitive stereo-metric satellites in China, TH-1 Satellite, is able to gain stereo images of three-line-array with resolution of 5 meters, multispectral images of 10 meters, and panchromatic high resolution images of 2 meters. The procedure between level 0 and level 1A of high resolution images is so called relative radiometric correction (RRC for short). The processing algorithm of high resolution images, with large volumes of data, is complicated and time consuming. In order to bring up the processing speed, people in industry commonly apply parallel processing techniques based on CPU or GPU. This article firstly introduces the whole process and each step of the algorithm - that is in application - of RRC for high resolution images in level 0; secondly, the theory and characteristics of MPI (Message Passing Interface) and OpenMP (Open Multi-Processing) parallel programming techniques is briefly described, as well as the superiority for parallel technique in image processing field; thirdly, aiming at each step of the algorithm in application and based on MPI+OpenMP hybrid paradigm, the parallelizability and the strategies of parallelism for three processing steps: Radiometric Correction, Splicing Pieces of TDICCD (Time Delay Integration Charge-Coupled Device) and Gray Level Adjustment among pieces of TDICCD are deeply discussed, and furthermore, deducts the theoretical acceleration rates of each step and the one of whole procedure, according to the processing styles and independence of calculation; for the step Splicing Pieces of TDICCD, two different strategies of parallelism are proposed, which are to be chosen with consideration of hardware capabilities; finally, series of experiments are carried out to verify the parallel algorithms by applying 2-meter panchromatic high resolution images of TH-1 Satellite, and the experimental results are analyzed. Strictly on the basis of former parallel algorithms, the programs in the experiments

  9. An improved model of Charge Transfer Inefficiency and correction algorithm for the Hubble Space Telescope

    CERN Document Server

    Massey, Richard; Cordes, Oliver; Marggraf, Ole; Israel, Holger; Miller, Lance; Hall, David; Cropper, Mark; Prod'homme, Thibaut; Niemi, Sami-Matias

    2014-01-01

    Charge-Coupled Device (CCD) detectors, widely used to obtain digital imaging, can be damaged by high energy radiation. Degraded images appear blurred, because of an effect known as Charge Transfer Inefficiency (CTI), which trails bright objects as the image is read out. It is often possible to correct most of the trailing during post-processing, by moving flux back to where it belongs. We compare several popular algorithms for this: quantifying the effect of their physical assumptions and tradeoffs between speed and accuracy. We combine their best elements to construct a more accurate model of damaged CCDs in the Hubble Space Telescope's Advanced Camera for Surveys/Wide Field Channel, and update it using data up to early 2013. Our algorithm now corrects 98% of CTI trailing in science exposures, a substantial improvement over previous work. Further progress will be fundamentally limited by the presence of read noise. Read noise is added after charge transfer so does not get trailed - but it is incorrectly untr...

  10. Correction.

    Science.gov (United States)

    2015-11-01

    In the article by Heuslein et al, which published online ahead of print on September 3, 2015 (DOI: 10.1161/ATVBAHA.115.305775), a correction was needed. Brett R. Blackman was added as the penultimate author of the article. The article has been corrected for publication in the November 2015 issue. PMID:26490278

  11. A simple algorithm for subregional striatal uptake analysis with partial volume correction in dopaminergic PET imaging

    International Nuclear Information System (INIS)

    In positron emission tomography (PET) of the dopaminergic system, quantitative measurements of nigrostriatal dopamine function are useful for differential diagnosis. A subregional analysis of striatal uptake enables the diagnostic performance to be more powerful. However, the partial volume effect (PVE) induces an underestimation of the true radioactivity concentration in small structures. This work proposes a simple algorithm for subregional analysis of striatal uptake with partial volume correction (PVC) in dopaminergic PET imaging. The PVC algorithm analyzes the separate striatal subregions and takes into account the PVE based on the recovery coefficient (RC). The RC is defined as the ratio of the PVE-uncorrected to PVE-corrected radioactivity concentration, and is derived from a combination of the traditional volume of interest (VOI) analysis and the large VOI technique. The clinical studies, comprising 11 patients with Parkinson's disease (PD) and 6 healthy subjects, were used to assess the impact of PVC on the quantitative measurements. Simulations on a numerical phantom that mimicked realistic healthy and neurodegenerative situations were used to evaluate the performance of the proposed PVC algorithm. In both the clinical and the simulation studies, the striatal-to-occipital ratio (SOR) values for the entire striatum and its subregions were calculated with and without PVC. In the clinical studies, the SOR values in each structure (caudate, anterior putamen, posterior putamen, putamen, and striatum) were significantly higher by using PVC in contrast to those without. Among the PD patients, the SOR values in each structure and quantitative disease severity ratings were shown to be significantly related only when PVC was used. For the simulation studies, the average absolute percentage error of the SOR estimates before and after PVC were 22.74% and 1.54% in the healthy situation, respectively; those in the neurodegenerative situation were 20.69% and 2

  12. An automated phase correction algorithm for retrieving permittivity and permeability of electromagnetic metamaterials

    Directory of Open Access Journals (Sweden)

    Z. X. Cao

    2014-06-01

    Full Text Available To retrieve complex-valued effective permittivity and permeability of electromagnetic metamaterials (EMMs based on resonant effect from scattering parameters using a complex logarithmic function is not inevitable. When complex values are expressed in terms of magnitude and phase, an infinite number of permissible phase angles is permissible due to the multi-valued property of complex logarithmic functions. Special attention needs to be paid to ensure continuity of the effective permittivity and permeability of lossy metamaterials as frequency sweeps. In this paper, an automated phase correction (APC algorithm is proposed to properly trace and compensate phase angles of the complex logarithmic function which may experience abrupt phase jumps near the resonant frequency region of the concerned EMMs, and hence the continuity of the effective optical properties of lossy metamaterials is ensured. The algorithm is then verified to extract effective optical properties from the simulated scattering parameters of the four different types of metamaterial media: a cut-wire cell array, a split ring resonator (SRR cell array, an electric-LC (E-LC resonator cell array, and a combined SRR and wire cell array respectively. The results demonstrate that the proposed algorithm is highly accurate and effective.

  13. Model-based correction algorithms improving the accuracy of hydrostatic level measurement on pressure vessels

    International Nuclear Information System (INIS)

    It is important to possess precise process information for an optimised valuation of the plant process conditions. Especially these information have a great priority as well as for the emergency operation and post accident management. The rapid and great transitions resulting from that are hardly to master by the used measuring devices. Spurious indications can occur the cause of which could be a modification of design conditions, specific transients of process and the damage of the measuring instrument itself respectively during accidents. Further more it would be desirable to get additional not measurable state variables in this situation. For solving those problems modern methods and procedures of process identification, parameter identification and plausibility analysis comprising correction algorithms become more and more important. These modern methods are used to solve the following problems - diagnosis of the process state on the basis of combination by measuring variables, analytical redundancy and linguistic declarations, - reconstruction of not directly measurable variables and parameters respectively - detection and identification of process faults and instrumentation faults (diagnosis) - reconfiguration of measuring signals (correction). The reconstruction of process state is thus a combination of measured quantity, reconstructed state variables and analytical redundancy using model-based measuring methods. The use of model based measuring methods has been investigated on the example of hydrostatic level measurement on horizontal steam generators. The results of experiments on pilot plants as well as comparison with calculations of empowered programs for instants ATHLET and methods of parameter identification serve as a verification of methods and algorithms, which were developed. This paper describe the main facts of this work

  14. A Modified Fuzzy C-Means Algorithm for Brain MR Image Segmentation and Bias Field Correction

    Institute of Scientific and Technical Information of China (English)

    Wen-Qian Deng; Xue-Mei Li; Xifeng Gao; Cai-Ming Zhang

    2016-01-01

    In quantitative brain image analysis, accurate brain tissue segmentation from brain magnetic resonance image (MRI) is a critical step. It is considered to be the most important and difficult issue in the field of medical image processing. The quality of MR images is influenced by partial volume effect, noise, and intensity inhomogeneity, which render the segmentation task extremely challenging. We present a novel fuzzy c-means algorithm (RCLFCM) for segmentation and bias field correction of brain MR images. We employ a new gray-difference coefficient and design a new impact factor to measure the effect of neighbor pixels, so that the robustness of anti-noise can be enhanced. Moreover, we redefine the objective function of FCM (fuzzy c-means) by adding the bias field estimation model to overcome the intensity inhomogeneity in the image and segment the brain MR images simultaneously. We also construct a new spatial function by combining pixel gray value dissimilarity with its membership, and make full use of the space information between pixels to update the membership. Compared with other state-of-the-art approaches by using similarity accuracy on synthetic MR images with different levels of noise and intensity inhomogeneity, the proposed algorithm generates the results with high accuracy and robustness to noise.

  15. A novel image-based motion correction algorithm on ultrasonic image

    Science.gov (United States)

    Wang, Xuan; Li, Yaqin; Li, Shigao

    2015-12-01

    Lung respiratory movement can cause errors in the operation of image navigation surgery and they are the main errors in the navigation system. To solve this problem, the image-based motion correction strategy should be proposed to quickly correct the respiratory motion in the image sequence. So, the commercial ultrasound machine can display contrast and tissue images simultaneously. In the paper, a convenient, simple and easy-to-use breathing model whose precision was close to the sub-voxel was proposed. The first, in the clinical case the low gray-level variation in the tissue images, motion parameters were first calculated according to the actual lung movement information of each point the tissue images are registered by using template matching with sum of absolute differences metric. Finally, the similar images are selected by a double-selection method which requires global and local threshold setting. The generic breathing model was constructed based on all the sample data. The results of experiments show the algorithm can reduce the original errors caused by breath movement heavily.

  16. Intensity Inhomogeneity Correction of Structural MR Images: A Data-Driven Approach to Define Input Algorithm Parameters.

    Science.gov (United States)

    Ganzetti, Marco; Wenderoth, Nicole; Mantini, Dante

    2016-01-01

    Intensity non-uniformity (INU) in magnetic resonance (MR) imaging is a major issue when conducting analyses of brain structural properties. An inaccurate INU correction may result in qualitative and quantitative misinterpretations. Several INU correction methods exist, whose performance largely depend on the specific parameter settings that need to be chosen by the user. Here we addressed the question of how to select the best input parameters for a specific INU correction algorithm. Our investigation was based on the INU correction algorithm implemented in SPM, but this can be in principle extended to any other algorithm requiring the selection of input parameters. We conducted a comprehensive comparison of indirect metrics for the assessment of INU correction performance, namely the coefficient of variation of white matter (CVWM), the coefficient of variation of gray matter (CVGM), and the coefficient of joint variation between white matter and gray matter (CJV). Using simulated MR data, we observed the CJV to be more accurate than CVWM and CVGM, provided that the noise level in the INU-corrected image was controlled by means of spatial smoothing. Based on the CJV, we developed a data-driven approach for selecting INU correction parameters, which could effectively work on actual MR images. To this end, we implemented an enhanced procedure for the definition of white and gray matter masks, based on which the CJV was calculated. Our approach was validated using actual T1-weighted images collected with 1.5 T, 3 T, and 7 T MR scanners. We found that our procedure can reliably assist the selection of valid INU correction algorithm parameters, thereby contributing to an enhanced inhomogeneity correction in MR images. PMID:27014050

  17. Intensity inhomogeneity correction of structural MR images: a data-driven approach to define input algorithm parameters

    Directory of Open Access Journals (Sweden)

    Marco eGanzetti

    2016-03-01

    Full Text Available Intensity non-uniformity (INU in magnetic resonance (MR imaging is a major issue when conducting analyses of brain structural properties. An inaccurate INU correction may result in qualitative and quantitative misinterpretations. Several INU correction methods exist, whose performance largely depend on the specific parameter settings that need to be chosen by the user. Here we addressed the question of how to select the best input parameters for a specific INU correction algorithm. Our investigation was based on the INU correction algorithm implemented in SPM, but this can be in principle extended to any other algorithm requiring the selection of input parameters. We conducted a comprehensive comparison of indirect metrics for the assessment of INU correction performance, namely the coefficient of variation of white matter (CV_WM, the coefficient of variation of gray matter (CV_GM, and the coefficient of joint variation between white matter and gray matter (CJV. Using simulated MR data, we observed the CJV to be more accurate than CV_WM and CV_GM, provided that the noise level in the INU-corrected image was controlled by means of spatial smoothing. Based on the CJV, we developed a data-driven approach for selecting INU correction parameters, which could effectively work on actual MR images. To this end, we implemented an enhanced procedure for the definition of white and gray matter masks, based on which the CJV was calculated. Our approach was validated using actual T1-weighted images collected with 1.5 T, 3 T and 7 T MR scanners. We found that our procedure can reliably assist the selection of valid INU correction algorithm parameters, thereby contributing to an enhanced inhomogeneity correction in MR images.

  18. Intensity Inhomogeneity Correction of Structural MR Images: A Data-Driven Approach to Define Input Algorithm Parameters

    Science.gov (United States)

    Ganzetti, Marco; Wenderoth, Nicole; Mantini, Dante

    2016-01-01

    Intensity non-uniformity (INU) in magnetic resonance (MR) imaging is a major issue when conducting analyses of brain structural properties. An inaccurate INU correction may result in qualitative and quantitative misinterpretations. Several INU correction methods exist, whose performance largely depend on the specific parameter settings that need to be chosen by the user. Here we addressed the question of how to select the best input parameters for a specific INU correction algorithm. Our investigation was based on the INU correction algorithm implemented in SPM, but this can be in principle extended to any other algorithm requiring the selection of input parameters. We conducted a comprehensive comparison of indirect metrics for the assessment of INU correction performance, namely the coefficient of variation of white matter (CVWM), the coefficient of variation of gray matter (CVGM), and the coefficient of joint variation between white matter and gray matter (CJV). Using simulated MR data, we observed the CJV to be more accurate than CVWM and CVGM, provided that the noise level in the INU-corrected image was controlled by means of spatial smoothing. Based on the CJV, we developed a data-driven approach for selecting INU correction parameters, which could effectively work on actual MR images. To this end, we implemented an enhanced procedure for the definition of white and gray matter masks, based on which the CJV was calculated. Our approach was validated using actual T1-weighted images collected with 1.5 T, 3 T, and 7 T MR scanners. We found that our procedure can reliably assist the selection of valid INU correction algorithm parameters, thereby contributing to an enhanced inhomogeneity correction in MR images. PMID:27014050

  19. A simplified procedure for correcting both errors and erasures of a Reed-Solomon code using the Euclidean algorithm

    Science.gov (United States)

    Truong, T. K.; Hsu, I. S.; Eastman, W. L.; Reed, I. S.

    1987-01-01

    It is well known that the Euclidean algorithm or its equivalent, continued fractions, can be used to find the error locator polynomial and the error evaluator polynomial in Berlekamp's key equation needed to decode a Reed-Solomon (RS) code. A simplified procedure is developed and proved to correct erasures as well as errors by replacing the initial condition of the Euclidean algorithm by the erasure locator polynomial and the Forney syndrome polynomial. By this means, the errata locator polynomial and the errata evaluator polynomial can be obtained, simultaneously and simply, by the Euclidean algorithm only. With this improved technique the complexity of time domain RS decoders for correcting both errors and erasures is reduced substantially from previous approaches. As a consequence, decoders for correcting both errors and erasures of RS codes can be made more modular, regular, simple, and naturally suitable for both VLSI and software implementation. An example illustrating this modified decoding procedure is given for a (15, 9) RS code.

  20. Geo-correction Algorithm Based on Equivalent RD Model for ScanSAR of HJ-1-C Satellite

    Directory of Open Access Journals (Sweden)

    Liu Jia-yin

    2014-06-01

    Full Text Available HJ-1-C satellite is the first Synthetic Aperture Radar (SAR satellite for civilian use in China, and it has a strip and scan mode. According to the characteristics of the ScanSAR of the HJ-1-C satellite, a geo-correction algorithm based on an equivalent RD model has been outlined in this paper on the basis of an ECS image processing algorithm and a traditional Range-Doppler location method. An azimuth mosaic was presented by a time series relationship, then the different burst was stitched by range, and the equivalent parameters were fitted to locations on the RD model. Finally, the ScanSAR image was geo-corrected. The HJ-1-C satellite data results showed that the location accuracy of ScanSAR for the HJ-1-C satellite was less than 100 m, and the geo-correction algorithm was realized in 10 s in fewer than 24 parallel cores.

  1. Full-wave acoustic and thermal modeling of transcranial ultrasound propagation and investigation of skull-induced aberration correction techniques: a feasibility study

    OpenAIRE

    Kyriakou, Adamos; Neufeld, Esra; Werner, Beat; Székely, Gábor; Kuster, Niels

    2015-01-01

    Background Transcranial focused ultrasound (tcFUS) is an attractive noninvasive modality for neurosurgical interventions. The presence of the skull, however, compromises the efficiency of tcFUS therapy, as its heterogeneous nature and acoustic characteristics induce significant distortion of the acoustic energy deposition, focal shifts, and thermal gain decrease. Phased-array transducers allow for partial compensation of skull-induced aberrations by application of precalculated phase and ampl...

  2. Full-wave acoustic and thermal modeling of transcranial ultrasound propagation and investigation of skull-induced aberration correction techniques: a feasibility study

    OpenAIRE

    Kyriakou, Adamos; Neufeld, Esra; Werner, Beat; Székely, Gábor; Kuster, Niels

    2015-01-01

    BACKGROUND Transcranial focused ultrasound (tcFUS) is an attractive noninvasive modality for neurosurgical interventions. The presence of the skull, however, compromises the efficiency of tcFUS therapy, as its heterogeneous nature and acoustic characteristics induce significant distortion of the acoustic energy deposition, focal shifts, and thermal gain decrease. Phased-array transducers allow for partial compensation of skull-induced aberrations by application of precalculated phase and amp...

  3. Spectrum correction algorithm for detectors in airborne radioactivity monitoring equipment NH-UAV based on a ratio processing method

    Energy Technology Data Exchange (ETDEWEB)

    Cao, Ye [Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Tang, Xiao-Bin, E-mail: tangxiaobin@nuaa.edu.cn [Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Jiangsu Key Laboratory of Nuclear Energy Equipment Materials Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Wang, Peng; Meng, Jia; Huang, Xi; Wen, Liang-Sheng [Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Chen, Da [Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Jiangsu Key Laboratory of Nuclear Energy Equipment Materials Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China)

    2015-10-11

    The unmanned aerial vehicle (UAV) radiation monitoring method plays an important role in nuclear accidents emergency. In this research, a spectrum correction algorithm about the UAV airborne radioactivity monitoring equipment NH-UAV was studied to measure the radioactive nuclides within a small area in real time and in a fixed place. The simulation spectra of the high-purity germanium (HPGe) detector and the lanthanum bromide (LaBr{sub 3}) detector in the equipment were obtained using the Monte Carlo technique. Spectrum correction coefficients were calculated after performing ratio processing techniques about the net peak areas between the double detectors on the detection spectrum of the LaBr{sub 3} detector according to the accuracy of the detection spectrum of the HPGe detector. The relationship between the spectrum correction coefficient and the size of the source term was also investigated. A good linear relation exists between the spectrum correction coefficient and the corresponding energy (R{sup 2}=0.9765). The maximum relative deviation from the real condition reduced from 1.65 to 0.035. The spectrum correction method was verified as feasible. - Highlights: • An airborne radioactivity monitoring equipment NH-UAV was developed to measure radionuclide after a nuclear accident. • A spectrum correction algorithm was proposed to obtain precise information on the detected radioactivity within a small area. • The spectrum correction method was verified as feasible. • The corresponding spectrum correction coefficients increase first and then stay constant.

  4. Spectrum correction algorithm for detectors in airborne radioactivity monitoring equipment NH-UAV based on a ratio processing method

    International Nuclear Information System (INIS)

    The unmanned aerial vehicle (UAV) radiation monitoring method plays an important role in nuclear accidents emergency. In this research, a spectrum correction algorithm about the UAV airborne radioactivity monitoring equipment NH-UAV was studied to measure the radioactive nuclides within a small area in real time and in a fixed place. The simulation spectra of the high-purity germanium (HPGe) detector and the lanthanum bromide (LaBr3) detector in the equipment were obtained using the Monte Carlo technique. Spectrum correction coefficients were calculated after performing ratio processing techniques about the net peak areas between the double detectors on the detection spectrum of the LaBr3 detector according to the accuracy of the detection spectrum of the HPGe detector. The relationship between the spectrum correction coefficient and the size of the source term was also investigated. A good linear relation exists between the spectrum correction coefficient and the corresponding energy (R2=0.9765). The maximum relative deviation from the real condition reduced from 1.65 to 0.035. The spectrum correction method was verified as feasible. - Highlights: • An airborne radioactivity monitoring equipment NH-UAV was developed to measure radionuclide after a nuclear accident. • A spectrum correction algorithm was proposed to obtain precise information on the detected radioactivity within a small area. • The spectrum correction method was verified as feasible. • The corresponding spectrum correction coefficients increase first and then stay constant

  5. Correction.

    Science.gov (United States)

    2016-02-01

    In the article by Guessous et al (Guessous I, Pruijm M, Ponte B, Ackermann D, Ehret G, Ansermot N, Vuistiner P, Staessen J, Gu Y, Paccaud F, Mohaupt M, Vogt B, Pechère-Bertschi A, Martin PY, Burnier M, Eap CB, Bochud M. Associations of ambulatory blood pressure with urinary caffeine and caffeine metabolite excretions. Hypertension. 2015;65:691–696. doi: 10.1161/HYPERTENSIONAHA.114.04512), which published online ahead of print December 8, 2014, and appeared in the March 2015 issue of the journal, a correction was needed.One of the author surnames was misspelled. Antoinette Pechère-Berstchi has been corrected to read Antoinette Pechère-Bertschi.The authors apologize for this error. PMID:26763012

  6. Optical Aberrations and Wavefront

    Directory of Open Access Journals (Sweden)

    Nihat Polat

    2014-08-01

    Full Text Available The deviation of light to create normal retinal image in the optical system is called aberration. Aberrations are divided two subgroup: low-order aberrations (defocus: spherical and cylindrical refractive errors and high-order aberrations (coma, spherical, trefoil, tetrafoil, quadrifoil, pentafoil, secondary astigmatism. Aberrations increase with aging. Spherical aberrations are compensated by positive corneal and negative lenticular spherical aberrations in youth. Total aberrations are elevated by positive corneal and positive lenticular spherical aberrations in elderly. In this study, we aimed to analyze the basic terms regarding optic aberrations which have gained significance recently. (Turk J Ophthalmol 2014; 44: 306-11

  7. Decoupling error for the atmospheric correction in ocean color remote sensing algorithms

    International Nuclear Information System (INIS)

    This paper studies the decoupling error associated with the atmospheric correction procedures in the ocean color remote sensing algorithms. The decoupling error is caused by the lack of proper consideration of multiple scattering between the atmospheric and ocean components. In other words, the atmosphere and ocean are not coupled properly. A vector radiative transfer model for the coupled atmosphere and ocean (CAO) system based on the successive order of scattering (SOS) method is used to study the error. The inherent optical properties (IOPs) of the ocean are provided by the most updated bio-optical models. Two wavelengths are used in the study, 412 and 555 nm. For a detector located just above the ocean interface, the decoupling errors range from 0.3% to 7% at 412 nm; and from 0.3% to 3% at 555 nm for zenith viewing angles smaller than 70 deg. The decoupling errors are significantly larger for larger zenith viewing angles for this detector. For a detector at the top of the atmosphere (TOA), it is hard to separate the decoupling error from the error introduced by the diffuse transmittance. If we assume the upwelling radiance is uniform just below the ocean surface when estimating the diffuse transmittance, the decoupling errors are from -4% to 8% for zenith viewing angles smaller than 70 deg.; and negative decoupling errors show up at mainly large zenith viewing angles.

  8. Algorithm of geometry correction for airborne 3D scanning laser radar

    Science.gov (United States)

    Liu, Yuan; Chen, Siying; Zhang, Yinchao; Ni, Guoqiang

    2009-11-01

    Airborne three-dimensional scanning laser radar is used for wholesale scanning exploration to the target realm, then three-dimensional model can be established and target features can be identified with the characteristics of echo signals. So it is used widely and have bright prospect in the modern military, scientific research, agriculture and industry. At present, most researchers are focus on higher precision, more reliability scanning system. As the scanning platform is fixed on the aircraft, the plane cannot keep horizontal for a long time, also impossibly for a long time fly in the route without deviation. Data acquisition and the subsequence calibration rely on different equipments. These equipments bring errors both in time and space. Accurate geometry correction can amend the errors created by the process of assembly. But for the errors caused by the plane during the flight, whole imaging process should be analyzed. Take the side-roll as an example; scanning direction is inclined, so that the scanning point deviates from the original place. New direction and coordinate is the aim to us. In this paper, errors caused by the side-roll, pitch, yaw and assembly are analyzed and the algorithm routine is designed.

  9. A GPU-based finite-size pencil beam algorithm with 3D-density correction for radiotherapy dose calculation

    Science.gov (United States)

    Gu, Xuejun; Jelen, Urszula; Li, Jinsheng; Jia, Xun; Jiang, Steve B.

    2011-06-01

    Targeting at the development of an accurate and efficient dose calculation engine for online adaptive radiotherapy, we have implemented a finite-size pencil beam (FSPB) algorithm with a 3D-density correction method on graphics processing unit (GPU). This new GPU-based dose engine is built on our previously published ultrafast FSPB computational framework (Gu et al 2009 Phys. Med. Biol. 54 6287-97). Dosimetric evaluations against Monte Carlo dose calculations are conducted on ten IMRT treatment plans (five head-and-neck cases and five lung cases). For all cases, there is improvement with the 3D-density correction over the conventional FSPB algorithm and for most cases the improvement is significant. Regarding the efficiency, because of the appropriate arrangement of memory access and the usage of GPU intrinsic functions, the dose calculation for an IMRT plan can be accomplished well within 1 s (except for one case) with this new GPU-based FSPB algorithm. Compared to the previous GPU-based FSPB algorithm without 3D-density correction, this new algorithm, though slightly sacrificing the computational efficiency (~5-15% lower), has significantly improved the dose calculation accuracy, making it more suitable for online IMRT replanning.

  10. A Robust In-Situ Warp-Correction Algorithm For VISAR Streak Camera Data at the National Ignition Facility

    Energy Technology Data Exchange (ETDEWEB)

    Labaria, George R. [Univ. of California, Santa Cruz, CA (United States); Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Warrick, Abbie L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Celliers, Peter M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kalantar, Daniel H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-01-12

    The National Ignition Facility (NIF) at the Lawrence Livermore National Laboratory is a 192-beam pulsed laser system for high-energy-density physics experiments. Sophisticated diagnostics have been designed around key performance metrics to achieve ignition. The Velocity Interferometer System for Any Reflector (VISAR) is the primary diagnostic for measuring the timing of shocks induced into an ignition capsule. The VISAR system utilizes three streak cameras; these streak cameras are inherently nonlinear and require warp corrections to remove these nonlinear effects. A detailed calibration procedure has been developed with National Security Technologies (NSTec) and applied to the camera correction analysis in production. However, the camera nonlinearities drift over time, affecting the performance of this method. An in-situ fiber array is used to inject a comb of pulses to generate a calibration correction in order to meet the timing accuracy requirements of VISAR. We develop a robust algorithm for the analysis of the comb calibration images to generate the warp correction that is then applied to the data images. Our algorithm utilizes the method of thin-plate splines (TPS) to model the complex nonlinear distortions in the streak camera data. In this paper, we focus on the theory and implementation of the TPS warp-correction algorithm for the use in a production environment.

  11. Correction

    CERN Multimedia

    2002-01-01

    The photo on the second page of the Bulletin n°48/2002, from 25 November 2002, illustrating the article «Spanish Visit to CERN» was published with a wrong caption. We would like to apologise for this mistake and so publish it again with the correct caption.   The Spanish delegation, accompanied by Spanish scientists at CERN, also visited the LHC superconducting magnet test hall (photo). From left to right: Felix Rodriguez Mateos of CERN LHC Division, Josep Piqué i Camps, Spanish Minister of Science and Technology, César Dopazo, Director-General of CIEMAT (Spanish Research Centre for Energy, Environment and Technology), Juan Antonio Rubio, ETT Division Leader at CERN, Manuel Aguilar-Benitez, Spanish Delegate to Council, Manuel Delfino, IT Division Leader at CERN, and Gonzalo León, Secretary-General of Scientific Policy to the Minister.

  12. Research and Implementation of Algorithm for Image Enhancement and Unwrapped Distortion Correction for SLVF Panoramic Night Vision Image

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Based on digital signal processor(DSP) and field programmable gate array(FPGA) techniques, the architecture of super large view field(SLVF) panoramic night vision image processing hardware platform was established. The panoramic unwrapping and correcting algorithm, up to a full 360°, based on coordinate rotation digital computer (CORDIC) and night vision image enhancement algorithm, based on histogram equalization theory and edge detection theory, was presented in this paper, with the purpose of processing night vision dynamic panoramic annular image. The annular image can be unwrapped and corrected to conventional rectangular panorama by the panoramic image processing algorithm, which uses the pipelined CORDIC configuration to realize a trigonometric function generator with high speed and high precision. Histogram equalization algorithm can perfectly enhance the contrast of the night vision image. Edge detection algorithm can be propitious to find and detect small dim dynamic targets in night vision circumstances. After abundant experiment, the algorithm for panoramic image processing and night vision image enhancement is successfully implemented in FPGA and DSP. The panoramic night vision image system is a compact device, with no external rotating parts. And the system can reliably and dynamically detect 360° SLVF panoramic night vision image.

  13. New Algorithm for Extracting Motion Information from PROPELLER Data and Head Motion Correction in T1-Weighted MRI.

    Science.gov (United States)

    Feng, Yanqiu; Chen, Wufan

    2005-01-01

    PROPELLER (Periodically Rotated Overlapping ParallEl Lines with Enhanced Reconstruction) MRI, proposed by J. G. Pipe [1], offers a novel and effective means for compensating motion. For the reconstruction of PROPLLER data, algorithms to reliably and accurately extract inter-strip motion from data in central overlapped area are crucial to motion artifacts suppression. When implemented on T1-weighted MR data, the reconstruction algorithm, with motion estimated by registration based on maximizing correlation energy in frequency domain (CF), produces images with low quality due to the inaccurate estimation of motion. In this paper, a new algorithm is proposed for motion estimation based on the registration by maximizing mutual information in spatial domain (MIS). Furthermore, the optimization process is initialized by CF algorithm, so the algorithm is abbreviated as CF-MIS algorithm in this paper. With phantom and in vivo MR imaging, the CF-MIS algorithm was shown to be of higher accuracy in rotation estimation than CF algorithm. Consequently, the head motion in T1-weighted PROPELLER MRI was better corrected. PMID:17282454

  14. Ground based measurements on reflectance towards validating atmospheric correction algorithms on IRS-P6 AWiFS data

    Science.gov (United States)

    Rani Sharma, Anu; Kharol, Shailesh Kumar; Kvs, Badarinath; Roy, P. S.

    In Earth observation, the atmosphere has a non-negligible influence on the visible and infrared radiation which is strong enough to modify the reflected electromagnetic signal and at-target reflectance. Scattering of solar irradiance by atmospheric molecules and aerosol generates path radiance, which increases the apparent surface reflectance over dark surfaces while absorption by aerosols and other molecules in the atmosphere causes loss of brightness to the scene, as recorded by the satellite sensor. In order to derive precise surface reflectance from satellite image data, it is indispensable to apply the atmospheric correction which serves to remove the effects of molecular and aerosol scattering. In the present study, we have implemented a fast atmospheric correction algorithm to IRS-P6 AWiFS satellite data which can effectively retrieve surface reflectance under different atmospheric and surface conditions. The algorithm is based on MODIS climatology products and simplified use of Second Simulation of Satellite Signal in Solar Spectrum (6S) radiative transfer code, which is used to generate look-up-tables (LUTs). The algorithm requires information on aerosol optical depth for correcting the satellite dataset. The proposed method is simple and easy to implement for estimating surface reflectance from the at sensor recorded signal, on a per pixel basis. The atmospheric correction algorithm has been tested for different IRS-P6 AWiFS False color composites (FCC) covering the ICRISAT Farm, Patancheru, Hyderabad, India under varying atmospheric conditions. Ground measurements of surface reflectance representing different land use/land cover, i.e., Red soil, Chick Pea crop, Groundnut crop and Pigeon Pea crop were conducted to validate the algorithm and found a very good match between surface reflectance and atmospherically corrected reflectance for all spectral bands. Further, we aggregated all datasets together and compared the retrieved AWiFS reflectance with

  15. Guided filter and adaptive learning rate based non-uniformity correction algorithm for infrared focal plane array

    Science.gov (United States)

    Sheng-Hui, Rong; Hui-Xin, Zhou; Han-Lin, Qin; Rui, Lai; Kun, Qian

    2016-05-01

    Imaging non-uniformity of infrared focal plane array (IRFPA) behaves as fixed-pattern noise superimposed on the image, which affects the imaging quality of infrared system seriously. In scene-based non-uniformity correction methods, the drawbacks of ghosting artifacts and image blurring affect the sensitivity of the IRFPA imaging system seriously and decrease the image quality visibly. This paper proposes an improved neural network non-uniformity correction method with adaptive learning rate. On the one hand, using guided filter, the proposed algorithm decreases the effect of ghosting artifacts. On the other hand, due to the inappropriate learning rate is the main reason of image blurring, the proposed algorithm utilizes an adaptive learning rate with a temporal domain factor to eliminate the effect of image blurring. In short, the proposed algorithm combines the merits of the guided filter and the adaptive learning rate. Several real and simulated infrared image sequences are utilized to verify the performance of the proposed algorithm. The experiment results indicate that the proposed algorithm can not only reduce the non-uniformity with less ghosting artifacts but also overcome the problems of image blurring in static areas.

  16. Fast and precise algorithms for calculating offset correction in single photon counting ASICs built in deep sub-micron technologies

    Science.gov (United States)

    Maj, P.

    2014-07-01

    An important trend in the design of readout electronics working in the single photon counting mode for hybrid pixel detectors is to minimize the single pixel area without sacrificing its functionality. This is the reason why many digital and analog blocks are made with the smallest, or next to smallest, transistors possible. This causes a problem with matching among the whole pixel matrix which is acceptable by designers and, of course, it should be corrected with the use of dedicated circuitry, which, by the same rule of minimizing devices, suffers from the mismatch. Therefore, the output of such a correction circuit, controlled by an ultra-small area DAC, is not only a non-linear function, but it is also often non-monotonic. As long as it can be used for proper correction of the DC operation points inside each pixel, it is acceptable, but the time required for correction plays an important role for both chip verification and the design of a big, multi-chip system. Therefore, we present two algorithms: a precise one and a fast one. The first algorithm is based on the noise hits profiles obtained during so called threshold scan procedures. The fast correction procedure is based on the trim DACs scan and it takes less than a minute in a SPC detector systems consisting of several thousands of pixels.

  17. Geo-correction Algorithm Based on Equivalent RD Model for ScanSAR of HJ-1-C Satellite

    OpenAIRE

    Liu Jia-yin; Wen Shuang-yan; Zhang Hong-yi; Hong Wen

    2014-01-01

    HJ-1-C satellite is the first Synthetic Aperture Radar (SAR) satellite for civilian use in China, and it has a strip and scan mode. According to the characteristics of the ScanSAR of the HJ-1-C satellite, a geo-correction algorithm based on an equivalent RD model has been outlined in this paper on the basis of an ECS image processing algorithm and a traditional Range-Doppler location method. An azimuth mosaic was presented by a time series relationship, then the different burst was stitched b...

  18. GPU-based finite-size pencil beam algorithm with 3D-density correction for radiotherapy dose calculation

    OpenAIRE

    Gu, Xuejun; Jelen, Urszula; Li, Jinsheng; Jia, Xun; Jiang, Steve B.

    2011-01-01

    Targeting at the development of an accurate and efficient dose calculation engine for online adaptive radiotherapy, we have implemented a finite size pencil beam (FSPB) algorithm with a 3D-density correction method on GPU. This new GPU-based dose engine is built on our previously published ultrafast FSPB computational framework. Dosimetric evaluations against Monte Carlo dose calculations are conducted on 10 IMRT treatment plans (5 head-and-neck cases and 5 lung cases). For all cases, there i...

  19. Evaluation of a prototype correction algorithm to reduce metal artefacts in flat detector computed tomography of scaphoid fixation screws

    Energy Technology Data Exchange (ETDEWEB)

    Filli, Lukas; Finkenstaedt, Tim; Andreisek, Gustav; Guggenberger, Roman [University Hospital of Zurich, Department of Diagnostic and Interventional Radiology, Zurich (Switzerland); Marcon, Magda [University Hospital of Zurich, Department of Diagnostic and Interventional Radiology, Zurich (Switzerland); University of Udine, Institute of Diagnostic Radiology, Department of Medical and Biological Sciences, Udine (Italy); Scholz, Bernhard [Imaging and Therapy Division, Siemens AG, Healthcare Sector, Forchheim (Germany); Calcagni, Maurizio [University Hospital of Zurich, Division of Plastic Surgery and Hand Surgery, Zurich (Switzerland)

    2014-12-15

    The aim of this study was to evaluate a prototype correction algorithm to reduce metal artefacts in flat detector computed tomography (FDCT) of scaphoid fixation screws. FDCT has gained interest in imaging small anatomic structures of the appendicular skeleton. Angiographic C-arm systems with flat detectors allow fluoroscopy and FDCT imaging in a one-stop procedure emphasizing their role as an ideal intraoperative imaging tool. However, FDCT imaging can be significantly impaired by artefacts induced by fixation screws. Following ethical board approval, commercially available scaphoid fixation screws were inserted into six cadaveric specimens in order to fix artificially induced scaphoid fractures. FDCT images corrected with the algorithm were compared to uncorrected images both quantitatively and qualitatively by two independent radiologists in terms of artefacts, screw contour, fracture line visibility, bone visibility, and soft tissue definition. Normal distribution of variables was evaluated using the Kolmogorov-Smirnov test. In case of normal distribution, quantitative variables were compared using paired Student's t tests. The Wilcoxon signed-rank test was used for quantitative variables without normal distribution and all qualitative variables. A p value of < 0.05 was considered to indicate statistically significant differences. Metal artefacts were significantly reduced by the correction algorithm (p < 0.001), and the fracture line was more clearly defined (p < 0.01). The inter-observer reliability was ''almost perfect'' (intra-class correlation coefficient 0.85, p < 0.001). The prototype correction algorithm in FDCT for metal artefacts induced by scaphoid fixation screws may facilitate intra- and postoperative follow-up imaging. (orig.)

  20. Phase Aberrations in Diffraction Microscopy

    CERN Document Server

    Marchesini, S; Barty, A; Cui, C; Howells, M R; Spence, J C H; Weierstall, U; Minor, A M

    2005-01-01

    In coherent X-ray diffraction microscopy the diffraction pattern generated by a sample illuminated with coherent x-rays is recorded, and a computer algorithm recovers the unmeasured phases to synthesize an image. By avoiding the use of a lens the resolution is limited, in principle, only by the largest scattering angles recorded. However, the imaging task is shifted from the experiment to the computer, and the algorithm's ability to recover meaningful images in the presence of noise and limited prior knowledge may produce aberrations in the reconstructed image. We analyze the low order aberrations produced by our phase retrieval algorithms. We present two methods to improve the accuracy and stability of reconstructions.

  1. High-Speed Atmospheric Correction Algorithm for Spectral Image Processing Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Generating land and ocean data products from NASA multispectral and hyperspectral imagery missions requires atmospheric correction, the removal of atmospheric...

  2. An experimental study of the scatter correction by using a beam-stop-array algorithm with digital breast tomosynthesis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ye-Seul; Park, Hye-Suk; Kim, Hee-Joung [Yonsei University, Wonju (Korea, Republic of); Choi, Young-Wook; Choi, Jae-Gu [Korea Electrotechnology Research Institute, Ansan (Korea, Republic of)

    2014-12-15

    Digital breast tomosynthesis (DBT) is a technique that was developed to overcome the limitations of conventional digital mammography by reconstructing slices through the breast from projections acquired at different angles. In developing and optimizing DBT, The x-ray scatter reduction technique remains a significant challenge due to projection geometry and radiation dose limitations. The most common approach to scatter reduction is a beam-stop-array (BSA) algorithm; however, this method raises concerns regarding the additional exposure involved in acquiring the scatter distribution. The compressed breast is roughly symmetric, and the scatter profiles from projections acquired at axially opposite angles are similar to mirror images. The purpose of this study was to apply the BSA algorithm with only two scans with a beam stop array, which estimates the scatter distribution with minimum additional exposure. The results of the scatter correction with angular interpolation were comparable to those of the scatter correction with all scatter distributions at each angle. The exposure increase was less than 13%. This study demonstrated the influence of the scatter correction obtained by using the BSA algorithm with minimum exposure, which indicates its potential for practical applications.

  3. Distributed Localization Algorithm for Wireless Sensor Network Based on Multidimensional Scaling and the Shortest Path Distance Correction

    Institute of Scientific and Technical Information of China (English)

    DING Yingqiang; DU Liufeng; YANG Ting; SUN Yugeng

    2009-01-01

    Sensor localization is crucial for the configuration and applications of wireless sensor network (WSN). A novel distributed localization algorithm, MDS-DC was proposed for wireless sensor network based on multidi-mensional scaling (MDS) and the shortest path distance correction. In MDS-DC, several local positioning regions with reasonable distribution were firstly constructed by an adaptive search algorithm, which ensures the mergence between the local relative maps of the adjacent local position regions and can reduce the number of common nodes in the network. Then, based on the relationships between the estimated distances and actual distances of anchors, the distance estimation vectors of sensors around anchors were corrected in each local positioning region. During the computations of the local relative coordinates, an iterative process, which is the combination of classical MDS algorithm and SMACOF algorithm, was applied. Finally, the global relative positions or absolute positions of sen-sors were obtained through merging the relative maps of all local positioning regions. Simulation results show that MDS-DC has better performances in positioning precision, energy efficiency and robustness to range error, which can meet the requirements of applications for sensor localization in WSN.

  4. Transmission-less attenuation correction in time-of-flight PET: analysis of a discrete iterative algorithm

    International Nuclear Information System (INIS)

    The maximum likelihood attenuation correction factors (MLACF) algorithm has been developed to calculate the maximum-likelihood estimate of the activity image and the attenuation sinogram in time-of-flight (TOF) positron emission tomography, using only emission data without prior information on the attenuation. We consider the case of a Poisson model of the data, in the absence of scatter or random background. In this case the maximization with respect to the attenuation factors can be achieved in a closed form and the MLACF algorithm works by updating the activity. Despite promising numerical results, the convergence of this algorithm has not been analysed. In this paper we derive the algorithm and demonstrate that the MLACF algorithm monotonically increases the likelihood, is asymptotically regular, and that the limit points of the iteration are stationary points of the likelihood. Because the problem is not convex, however, the limit points might be saddle points or local maxima. To obtain some empirical insight into the latter question, we present data obtained by applying MLACF to 2D simulated TOF data, using a large number of iterations and different initializations. (paper)

  5. Stack emission monitoring using non-dispersive infrared spectroscopy with an optimized nonlinear absorption cross interference correction algorithm

    Directory of Open Access Journals (Sweden)

    Y. W. Sun

    2013-08-01

    Full Text Available In this paper, we present an optimized analysis algorithm for non-dispersive infrared (NDIR to in situ monitor stack emissions. The proposed algorithm simultaneously compensates for nonlinear absorption and cross interference among different gases. We present a mathematical derivation for the measurement error caused by variations in interference coefficients when nonlinear absorption occurs. The proposed algorithm is derived from a classical one and uses interference functions to quantify cross interference. The interference functions vary proportionally with the nonlinear absorption. Thus, interference coefficients among different gases can be modeled by the interference functions whether gases are characterized by linear or nonlinear absorption. In this study, the simultaneous analysis of two components (CO2 and CO serves as an example for the validation of the proposed algorithm. The interference functions in this case can be obtained by least-squares fitting with third-order polynomials. Experiments show that the results of cross interference correction are improved significantly by utilizing the fitted interference functions when nonlinear absorptions occur. The dynamic measurement ranges of CO2 and CO are improved by about a factor of 1.8 and 3.5, respectively. A commercial analyzer with high accuracy was used to validate the CO and CO2 measurements derived from the NDIR analyzer prototype in which the new algorithm was embedded. The comparison of the two analyzers show that the prototype works well both within the linear and nonlinear ranges.

  6. Spectrum correction algorithm for detectors in airborne radioactivity monitoring equipment NH-UAV based on a ratio processing method

    Science.gov (United States)

    Cao, Ye; Tang, Xiao-Bin; Wang, Peng; Meng, Jia; Huang, Xi; Wen, Liang-Sheng; Chen, Da

    2015-10-01

    The unmanned aerial vehicle (UAV) radiation monitoring method plays an important role in nuclear accidents emergency. In this research, a spectrum correction algorithm about the UAV airborne radioactivity monitoring equipment NH-UAV was studied to measure the radioactive nuclides within a small area in real time and in a fixed place. The simulation spectra of the high-purity germanium (HPGe) detector and the lanthanum bromide (LaBr3) detector in the equipment were obtained using the Monte Carlo technique. Spectrum correction coefficients were calculated after performing ratio processing techniques about the net peak areas between the double detectors on the detection spectrum of the LaBr3 detector according to the accuracy of the detection spectrum of the HPGe detector. The relationship between the spectrum correction coefficient and the size of the source term was also investigated. A good linear relation exists between the spectrum correction coefficient and the corresponding energy (R2=0.9765). The maximum relative deviation from the real condition reduced from 1.65 to 0.035. The spectrum correction method was verified as feasible.

  7. Intraocular Lens Multifocality Combined with the Compensation for Corneal Spherical Aberration:A New Concept ofPresbyopia-CorrectingIntraocular Lens

    Directory of Open Access Journals (Sweden)

    Reiner Friedrich

    2012-10-01

    Full Text Available The outcomes of a prospective consecutive study aimed at evaluating the visual and refractive benefit after cataract surgery with the implantation of the aspheric diffractive multifocal intraocular lens (IOL Tecnis ZMB00 (Abbott Medical Optics are reported. A total of 31 eyes of 19 patients (age range, 40 to 81 years underwent phacoemulsification surgery with implantation of this aspheric multifocal IOL. At 6 months after surgery, postoperative spherical equivalent was within ±1.00 D in 96.8% of eyes, with 94.7% of patients presenting a postoperative binocular far LogMAR uncorrected visual acuity (UCVA of 0.1 or better. Far best-corrected distance VA improved significantly (p < 0.01, with postoperative values of 0.1 or better in 96.8% of eyes. Postoperative near UCVA was 0.10 (equivalent to J1 or better in 93.55% of eyes. Furthermore, the IOL power was found to be very poorly correlated with the postoperative far LogMAR (r = 0.13 and near UCVA (r = 0.13. In conclusion, the aspheric diffractive multifocal IOL Tecnis ZMB00 provides a restoration of the far and near visual function after phacoemulsification surgery for cataract removal or presbyopia correction, which is predictable and independent from the optical power of the implanted IOL.

  8. Upper Bounds on the Number of Errors Corrected by the Koetter–Vardy Algorithm

    DEFF Research Database (Denmark)

    Justesen, Jørn

    2007-01-01

    By introducing a few simplifying assumptions we derive a simple condition for successful decoding using the Koetter-Vardy algorithm for soft-decision decoding of Reed-Solomon codes. We show that the algorithm has a significant advantage over hard decision decoding when the code rate is low, when ...... two or more sets of received symbols have substantially different reliabilities, or when the number of alternative transmitted symbols is very small....

  9. Evaluation of Radiometric and Atmospheric Correction Algorithms for Aboveground Forest Biomass Estimation Using Landsat 5 TM Data

    Directory of Open Access Journals (Sweden)

    Pablito M. López-Serrano

    2016-04-01

    Full Text Available Solar radiation is affected by absorption and emission phenomena during its downward trajectory from the Sun to the Earth’s surface and during the upward trajectory detected by satellite sensors. This leads to distortion of the ground radiometric properties (reflectance recorded by satellite images, used in this study to estimate aboveground forest biomass (AGB. Atmospherically-corrected remote sensing data can be used to estimate AGB on a global scale and with moderate effort. The objective of this study was to evaluate four atmospheric correction algorithms (for surface reflectance, ATCOR2 (Atmospheric Correction for Flat Terrain, COST (Cosine of the Sun Zenith Angle, FLAASH (Fast Line-of-sight Atmospheric Analysis of Spectral Hypercubes and 6S (Second Simulation of Satellite Signal in the Solar, and one radiometric correction algorithm (for reflectance at the sensor ToA (Apparent Reflectance at the Top of Atmosphere to estimate AGB in temperate forest in the northeast of the state of Durango, Mexico. The AGB was estimated from Landsat 5 TM imagery and ancillary information from a digital elevation model (DEM using the non-parametric multivariate adaptive regression splines (MARS technique. Field reference data for the model training were collected by systematic sampling of 99 permanent forest growth and soil research sites (SPIFyS established during the winter of 2011. The following predictor variables were identified in the MARS model: Band 7, Band 5, slope (β, Wetness Index (WI, NDVI and MSAVI2. After cross-validation, 6S was found to be the optimal model for estimating AGB (R2 = 0.71 and RMSE = 33.5 Mg·ha−1; 37.61% of the average stand biomass. We conclude that atmospheric and radiometric correction of satellite images can be used along with non-parametric techniques to estimate AGB with acceptable accuracy.

  10. A GPU-based finite-size pencil beam algorithm with 3D-density correction for radiotherapy dose calculation

    CERN Document Server

    Gu, Xuejun; Li, Jinsheng; Jia, Xun; Jiang, Steve B

    2011-01-01

    Targeting at developing an accurate and efficient dose calculation engine for online adaptive radiotherapy, we have implemented a finite size pencil beam (FSPB) algorithm with a 3D-density correction method on GPU. This new GPU-based dose engine is built on our previously published ultrafast FSPB computational framework [Gu et al. Phys. Med. Biol. 54 6287-97, 2009]. Dosimetric evaluations against MCSIM Monte Carlo dose calculations are conducted on 10 IMRT treatment plans with heterogeneous treatment regions (5 head-and-neck cases and 5 lung cases). For head and neck cases, when cavities exist near the target, the improvement with the 3D-density correction over the conventional FSPB algorithm is significant. However, when there are high-density dental filling materials in beam paths, the improvement is small and the accuracy of the new algorithm is still unsatisfactory. On the other hand, significant improvement of dose calculation accuracy is observed in all lung cases. Especially when the target is in the m...

  11. Evaluation of Residual Static Corrections by Hybrid Genetic Algorithm Steepest Ascent Autostatics Inversion.Application southern Algerian fields

    Science.gov (United States)

    Eladj, Said; bansir, fateh; ouadfeul, sid Ali

    2016-04-01

    The application of genetic algorithm starts with an initial population of chromosomes representing a "model space". Chromosome chains are preferentially Reproduced based on Their fitness Compared to the total population. However, a good chromosome has a Greater opportunity to Produce offspring Compared To other chromosomes in the population. The advantage of the combination HGA / SAA is the use of a global search approach on a large population of local maxima to Improve Significantly the performance of the method. To define the parameters of the Hybrid Genetic Algorithm Steepest Ascent Auto Statics (HGA / SAA) job, we Evaluated by testing in the first stage of "Steepest Ascent," the optimal parameters related to the data used. 1- The number of iterations "Number of hill climbing iteration" is equal to 40 iterations. This parameter defines the participation of the algorithm "SA", in this hybrid approach. 2- The minimum eigenvalue for SA '= 0.8. This is linked to the quality of data and S / N ratio. To find an implementation performance of hybrid genetic algorithms in the inversion for estimating of the residual static corrections, tests Were Performed to determine the number of generation of HGA / SAA. Using the values of residual static corrections already calculated by the Approaches "SAA and CSAA" learning has Proved very effective in the building of the cross-correlation table. To determine the optimal number of generation, we Conducted a series of tests ranging from [10 to 200] generations. The application on real seismic data in southern Algeria allowed us to judge the performance and capacity of the inversion with this hybrid method "HGA / SAA". This experience Clarified the influence of the corrections quality estimated from "SAA / CSAA" and the optimum number of generation hybrid genetic algorithm "HGA" required to have a satisfactory performance. Twenty (20) generations Were enough to Improve continuity and resolution of seismic horizons. This Will allow

  12. A corrected and generalized successive random additions algorithm for simulating fractional levy motions

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Hui-Hai; Bodvarsson, Gudmundur S.; Lu, Silong; Molz, Fred J.

    2002-05-29

    Simulation of subsurface heterogeneity is important for modeling subsurface flow and transport processes. Previous studies have indicated that subsurface property variations can often be characterized by fractional Brownian motion (fBm) or (truncated) fractional Levy motion (fLm). Because Levy-stable distributions have many novel and often unfamiliar properties, studies on generating fLm distributions are rare in the literature. In this study, we generalize a relatively simple and computationally efficient successive random additions (SRA) algorithm, originally developed for generating Gaussian fractals, to simulate fLm distributions. We also propose an additional important step in response to continued observations that the traditional SRA algorithm often generates fractal distributions having poor scaling and correlation properties. Finally, the generalized and modified SRA algorithm is validated through numerical tests.

  13. Depth-resolved analytical model and correction algorithm for photothermal optical coherence tomography.

    Science.gov (United States)

    Lapierre-Landry, Maryse; Tucker-Schwartz, Jason M; Skala, Melissa C

    2016-07-01

    Photothermal OCT (PT-OCT) is an emerging molecular imaging technique that occupies a spatial imaging regime between microscopy and whole body imaging. PT-OCT would benefit from a theoretical model to optimize imaging parameters and test image processing algorithms. We propose the first analytical PT-OCT model to replicate an experimental A-scan in homogeneous and layered samples. We also propose the PT-CLEAN algorithm to reduce phase-accumulation and shadowing, two artifacts found in PT-OCT images, and demonstrate it on phantoms and in vivo mouse tumors. PMID:27446693

  14. Probably approximately correct nature's algorithms for learning and prospering in a complex world

    CERN Document Server

    Valiant, Leslie

    2013-01-01

    We have effective theories for very few things. Gravity is one, electromagnetism another. But for most things-whether as mundane as finding a mate or as major as managing an economy-our theories are lousy or nonexistent. Fortunately, we don't need them, any more than a fish needs a theory of water to swim; we're able to muddle through. But how do we do it? In Probably Approximately Correct, computer scientist Leslie Valiant presents a theory of the theoryless. The key is "probably approximately correct" learning, Valiant's model of how anything can act without needing to understand

  15. The use of anatomical information for molecular image reconstruction algorithms: Attention/Scatter correction, motion compensation, and noise reduction

    Energy Technology Data Exchange (ETDEWEB)

    Chun, Se Young [School of Electrical and Computer Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan (Korea, Republic of)

    2016-03-15

    PET and SPECT are important tools for providing valuable molecular information about patients to clinicians. Advances in nuclear medicine hardware technologies and statistical image reconstruction algorithms enabled significantly improved image quality. Sequentially or simultaneously acquired anatomical images such as CT and MRI from hybrid scanners are also important ingredients for improving the image quality of PET or SPECT further. High-quality anatomical information has been used and investigated for attenuation and scatter corrections, motion compensation, and noise reduction via post-reconstruction filtering and regularization in inverse problems. In this article, we will review works using anatomical information for molecular image reconstruction algorithms for better image quality by describing mathematical models, discussing sources of anatomical information for different cases, and showing some examples.

  16. The Use of Anatomical Information for Molecular Image Reconstruction Algorithms: Attenuation/Scatter Correction, Motion Compensation, and Noise Reduction.

    Science.gov (United States)

    Chun, Se Young

    2016-03-01

    PET and SPECT are important tools for providing valuable molecular information about patients to clinicians. Advances in nuclear medicine hardware technologies and statistical image reconstruction algorithms enabled significantly improved image quality. Sequentially or simultaneously acquired anatomical images such as CT and MRI from hybrid scanners are also important ingredients for improving the image quality of PET or SPECT further. High-quality anatomical information has been used and investigated for attenuation and scatter corrections, motion compensation, and noise reduction via post-reconstruction filtering and regularization in inverse problems. In this article, we will review works using anatomical information for molecular image reconstruction algorithms for better image quality by describing mathematical models, discussing sources of anatomical information for different cases, and showing some examples. PMID:26941855

  17. A Label Correcting Algorithm for Partial Disassembly Sequences in the Production Planning for End-of-Life Products

    Directory of Open Access Journals (Sweden)

    Pei-Fang (Jennifer Tsai

    2012-01-01

    Full Text Available Remanufacturing of used products has become a strategic issue for cost-sensitive businesses. Due to the nature of uncertain supply of end-of-life (EoL products, the reverse logistic can only be sustainable with a dynamic production planning for disassembly process. This research investigates the sequencing of disassembly operations as a single-period partial disassembly optimization (SPPDO problem to minimize total disassembly cost. AND/OR graph representation is used to include all disassembly sequences of a returned product. A label correcting algorithm is proposed to find an optimal partial disassembly plan if a specific reusable subpart is retrieved from the original return. Then, a heuristic procedure that utilizes this polynomial-time algorithm is presented to solve the SPPDO problem. Numerical examples are used to demonstrate the effectiveness of this solution procedure.

  18. A GPU-based finite-size pencil beam algorithm with 3D-density correction for radiotherapy dose calculation

    OpenAIRE

    Gu, Xuejun; Jelen, Urszula; Li, Jinsheng; Jia, Xun; Jiang, Steve B.

    2011-01-01

    Targeting at the development of an accurate and efficient dose calculation engine for online adaptive radiotherapy, we have implemented a finite size pencil beam (FSPB) algorithm with a 3D-density correction method on GPU. This new GPU-based dose engine is built on our previously published ultrafast FSPB computational framework [Gu et al. Phys. Med. Biol. 54 6287-97, 2009]. Dosimetric evaluations against Monte Carlo dose calculations are conducted on 10 IMRT treatment plans (5 head-and-neck c...

  19. A spline-regularized minimal residual algorithm for iterative attenuation correction in SPECT

    International Nuclear Information System (INIS)

    In SPECT, regularization is necessary to avoid divergence of the iterative algorithms used for non-uniform attenuation compensation. In this paper, we propose a spline-based regularization method for the minimal residual algorithm. First, the acquisition noise is filtered using a statistical model involving spline smoothing so that the filtered projections belong to a Sobolev space with specific continuity and derivability properties. Then, during the iterative reconstruction procedure, the continuity of the inverse Radon transform between Sobolev spaces is used to design a spline-regularized filtered backprojection method, by which the known regularity properties of the projections determine those of the corresponding reconstructed slices. This ensures that the activity distributions estimated at each iteration present regularity properties, which avoids computational noise amplification, thus stabilizing the iterative process. Analytical and Monte Carlo simulations are used to show that the proposed spline-regularized minimal residual algorithm converges to a satisfactory stable solution in terms of restored activity and homogeneity, using at most 25 iterations, whereas the non regularized version of the algorithm diverges. Choosing the number of iterations is therefore no longer a critical issue for this reconstruction procedure. (author)

  20. Atomic-resolution studies of In{sub 2}O{sub 3}-ZnO compounds on aberration-corrected electron microscopes

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Wentao

    2009-10-23

    In this work, the characteristic inversion domain microstructures of In{sub 2}O{sub 3}(ZnO){sub m} (m=30) compounds were investigated by TEM methods. At bright-atom contrast condition, atomically resolved HR-TEM images of In{sub 2}O{sub 3}(ZnO){sub 30} were successfully acquired in [1 anti 100] zone axis of ZnO, with projected metal columns of {proportional_to}1.6 A well resolved. From contrast maxima in the TEM images, local lattice distortions at the pyramidal inversion domain boundaries were observed for the first time. Lattice displacements and the strain field in two-dimensions were visualized and measured using the 'DALI' algorithm. Atomically resolved single shot and focal series images of In{sub 2}O{sub 3}(ZnO){sub 30} were achieved in both zone axes of ZnO, [1 anti 100] and [2 anti 1 anti 10], respectively. The electron waves at the exit-plane were successfully reconstructed using the software package 'TrueImage'. Finally, a three dimensional atomic structure model for the pyramidal IDB was proposed, with an In distribution of 10%, 20%, 40%, 20% and 10% of In contents over 5 atom columns along basal planes, respectively. Through a detailed structural study of In{sub 2}O{sub 3}(ZnO){sub m} compounds by using phase-contrast and Z-contrast imaging at atomic resolution, In{sup 3+} atoms are determined with trigonal bi-pyramidal co-ordination and are distributed at the pyramidal IDBs. (orig.)

  1. A new algorithm for detecting and correcting bad pixels in infrared images

    Directory of Open Access Journals (Sweden)

    Andrés David Restrepo Girón

    2012-10-01

    Full Text Available An image processing algorithm detects and replaces abnormal pixels individually, highlighting them amongst their neighbours in a sequence of thermal images without affecting overall texture, like classical filtering does. Bad pixels from manufacture or constant use of a CCD device in an IR camera are thus detected and replaced with a very good success rate, thereby reducing the risk of bad interpretation. Some thermal sequences from CFRP plates, taken by a Cincinnati Electronics InSb IR camera, were used for developing and testing this algorithm. The results were compared to a detailed list of bad pixels given by the manufacturer (about 70% coincidence. This work becomes relevant considering that the number of papers on this subject is low; most of them talk about astronomical image pre-processing. Moreover, thermo graphic non-destructive testing (TNDT techniques are gaining popularity in Colombia at introductory levels in industrial sectors such as energy generation and transmission, sugar production and military aeronautics.

  2. Static scene statistical algorithm for nonuniformity correction in focal-plane arrays

    Science.gov (United States)

    Catarius, Adrian M.; Seal, Michael D.

    2015-10-01

    A static scene statistical nonuniformity correction (S3NUC) method was developed based on the higher-order moments of a linear statistical model of a photodetection process. S3NUC relieves the requirement for calibrated targets or a moving scene for NUC by utilizing two data sets of different intensities but requires low scene intensity levels. The first-, second-, and third-order moments of the two data sets are used to estimate the gain and bias values for the detectors in a focal-plane array (FPA). These gain and bias values may then be used to correct the nonuniformities between detectors or to initialize other continuous calibration methods. S3NUC was successfully applied to simulated data as well as measured data at visible wavelengths.

  3. Lorentz force correction to the Boltzmann radiation transport equation and its implications for Monte Carlo algorithms

    International Nuclear Information System (INIS)

    To establish a theoretical framework for generalizing Monte Carlo transport algorithms by adding external electromagnetic fields to the Boltzmann radiation transport equation in a rigorous and consistent fashion. Using first principles, the Boltzmann radiation transport equation is modified by adding a term describing the variation of the particle distribution due to the Lorentz force. The implications of this new equation are evaluated by investigating the validity of Fano’s theorem. Additionally, Lewis’ approach to multiple scattering theory in infinite homogeneous media is redefined to account for the presence of external electromagnetic fields. The equation is modified and yields a description consistent with the deterministic laws of motion as well as probabilistic methods of solution. The time-independent Boltzmann radiation transport equation is generalized to account for the electromagnetic forces in an additional operator similar to the interaction term. Fano’s and Lewis’ approaches are stated in this new equation. Fano’s theorem is found not to apply in the presence of electromagnetic fields. Lewis’ theory for electron multiple scattering and moments, accounting for the coupling between the Lorentz force and multiple elastic scattering, is found. However, further investigation is required to develop useful algorithms for Monte Carlo and deterministic transport methods. To test the accuracy of Monte Carlo transport algorithms in the presence of electromagnetic fields, the Fano cavity test, as currently defined, cannot be applied. Therefore, new tests must be designed for this specific application. A multiple scattering theory that accurately couples the Lorentz force with elastic scattering could improve Monte Carlo efficiency. The present study proposes a new theoretical framework to develop such algorithms. (paper)

  4. Algorithmic Verification of Forward Correctability%前向可修正属性算术验证的研究

    Institute of Scientific and Technical Information of China (English)

    吴海玲; 周从华; 鞠时光; 王基

    2011-01-01

    目前验证前向可修正属性的"展开方法"是不完备的,即当"展开定理"的局部条件不满足时,不能判断出系统不满足前向可修正属性.为此,提出一种基于状态转换系统的前向可修正属性验证方法,该方法将前向可修正属性的验证归约为可达性问题,进而可借助可达性检测技术完成属性的验证.该方法是完备的,且当属性不成立时,可以给出使属性失效的反例,反例的给出对非法信息流的消除和控制具有直接的帮助.最后,通过磁臂隐通道的例子说明了方法的有效性和实用性.%Due to the incompleteness of the "Unwinding Theorem",a system can't be judged to fail to satisfy the forward correctability, when some local conditions of "Unwinding Theorem" are not satisfied. This paper proposed an algorithmic verification technique to check the forward correctability based on the state transition system The technique reduces forward correctability checking to the reachability problem and the reduction enables us to use the reachability checking technique to perform forward correctability checking. Our method is complete and it can give a counter-exampies to control and eliminate the illegal information flow when a system fails to satisfy the forward correctability. Finally,Disk-arm Convert Channel illustrates the effectiveness and practicality.

  5. Nonuniform Illumination Correction Algorithm for Underwater Images Using Maximum Likelihood Estimation Method

    Directory of Open Access Journals (Sweden)

    Sonali Sachin Sankpal

    2016-01-01

    Full Text Available Scattering and absorption of light is main reason for limited visibility in water. The suspended particles and dissolved chemical compounds in water are also responsible for scattering and absorption of light in water. The limited visibility in water results in degradation of underwater images. The visibility can be increased by using artificial light source in underwater imaging system. But the artificial light illuminates the scene in a nonuniform fashion. It produces bright spot at the center with the dark region at surroundings. In some cases imaging system itself creates dark region in the image by producing shadow on the objects. The problem of nonuniform illumination is neglected by the researchers in most of the image enhancement techniques of underwater images. Also very few methods are discussed showing the results on color images. This paper suggests a method for nonuniform illumination correction for underwater images. The method assumes that natural underwater images are Rayleigh distributed. This paper used maximum likelihood estimation of scale parameter to map distribution of image to Rayleigh distribution. The method is compared with traditional methods for nonuniform illumination correction using no-reference image quality metrics like average luminance, average information entropy, normalized neighborhood function, average contrast, and comprehensive assessment function.

  6. A Physically Based Algorithm for Non-Blackbody Correction of Cloud-Top Temperature and Application to Convection Study

    Science.gov (United States)

    Wang, Chunpeng; Lou, Zhengzhao Johnny; Chen, Xiuhong; Zeng, Xiping; Tao, Wei-Kuo; Huang, Xianglei

    2014-01-01

    Cloud-top temperature (CTT) is an important parameter for convective clouds and is usually different from the 11-micrometers brightness temperature due to non-blackbody effects. This paper presents an algorithm for estimating convective CTT by using simultaneous passive [Moderate Resolution Imaging Spectroradiometer (MODIS)] and active [CloudSat 1 Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO)] measurements of clouds to correct for the non-blackbody effect. To do this, a weighting function of the MODIS 11-micrometers band is explicitly calculated by feeding cloud hydrometer profiles from CloudSat and CALIPSO retrievals and temperature and humidity profiles based on ECMWF analyses into a radiation transfer model.Among 16 837 tropical deep convective clouds observed by CloudSat in 2008, the averaged effective emission level (EEL) of the 11-mm channel is located at optical depth; approximately 0.72, with a standard deviation of 0.3. The distance between the EEL and cloud-top height determined by CloudSat is shown to be related to a parameter called cloud-top fuzziness (CTF), defined as the vertical separation between 230 and 10 dBZ of CloudSat radar reflectivity. On the basis of these findings a relationship is then developed between the CTF and the difference between MODIS 11-micrometers brightness temperature and physical CTT, the latter being the non-blackbody correction of CTT. Correction of the non-blackbody effect of CTT is applied to analyze convective cloud-top buoyancy. With this correction, about 70% of the convective cores observed by CloudSat in the height range of 6-10 km have positive buoyancy near cloud top, meaning clouds are still growing vertically, although their final fate cannot be determined by snapshot observations.

  7. Ultra-low dose CT attenuation correction for PET/CT: analysis of sparse view data acquisition and reconstruction algorithms.

    Science.gov (United States)

    Rui, Xue; Cheng, Lishui; Long, Yong; Fu, Lin; Alessio, Adam M; Asma, Evren; Kinahan, Paul E; De Man, Bruno

    2015-10-01

    For PET/CT systems, PET image reconstruction requires corresponding CT images for anatomical localization and attenuation correction. In the case of PET respiratory gating, multiple gated CT scans can offer phase-matched attenuation and motion correction, at the expense of increased radiation dose. We aim to minimize the dose of the CT scan, while preserving adequate image quality for the purpose of PET attenuation correction by introducing sparse view CT data acquisition.We investigated sparse view CT acquisition protocols resulting in ultra-low dose CT scans designed for PET attenuation correction. We analyzed the tradeoffs between the number of views and the integrated tube current per view for a given dose using CT and PET simulations of a 3D NCAT phantom with lesions inserted into liver and lung. We simulated seven CT acquisition protocols with {984, 328, 123, 41, 24, 12, 8} views per rotation at a gantry speed of 0.35 s. One standard dose and four ultra-low dose levels, namely, 0.35 mAs, 0.175 mAs, 0.0875 mAs, and 0.043 75 mAs, were investigated. Both the analytical Feldkamp, Davis and Kress (FDK) algorithm and the Model Based Iterative Reconstruction (MBIR) algorithm were used for CT image reconstruction. We also evaluated the impact of sinogram interpolation to estimate the missing projection measurements due to sparse view data acquisition. For MBIR, we used a penalized weighted least squares (PWLS) cost function with an approximate total-variation (TV) regularizing penalty function. We compared a tube pulsing mode and a continuous exposure mode for sparse view data acquisition. Global PET ensemble root-mean-squares-error (RMSE) and local ensemble lesion activity error were used as quantitative evaluation metrics for PET image quality.With sparse view sampling, it is possible to greatly reduce the CT scan dose when it is primarily used for PET attenuation correction with little or no measureable effect on the PET image. For the four ultra-low dose levels

  8. Ultra-low dose CT attenuation correction for PET/CT: analysis of sparse view data acquisition and reconstruction algorithms

    International Nuclear Information System (INIS)

    For PET/CT systems, PET image reconstruction requires corresponding CT images for anatomical localization and attenuation correction. In the case of PET respiratory gating, multiple gated CT scans can offer phase-matched attenuation and motion correction, at the expense of increased radiation dose. We aim to minimize the dose of the CT scan, while preserving adequate image quality for the purpose of PET attenuation correction by introducing sparse view CT data acquisition.We investigated sparse view CT acquisition protocols resulting in ultra-low dose CT scans designed for PET attenuation correction. We analyzed the tradeoffs between the number of views and the integrated tube current per view for a given dose using CT and PET simulations of a 3D NCAT phantom with lesions inserted into liver and lung. We simulated seven CT acquisition protocols with {984, 328, 123, 41, 24, 12, 8} views per rotation at a gantry speed of 0.35 s. One standard dose and four ultra-low dose levels, namely, 0.35 mAs, 0.175 mAs, 0.0875 mAs, and 0.043 75 mAs, were investigated. Both the analytical Feldkamp, Davis and Kress (FDK) algorithm and the Model Based Iterative Reconstruction (MBIR) algorithm were used for CT image reconstruction. We also evaluated the impact of sinogram interpolation to estimate the missing projection measurements due to sparse view data acquisition. For MBIR, we used a penalized weighted least squares (PWLS) cost function with an approximate total-variation (TV) regularizing penalty function. We compared a tube pulsing mode and a continuous exposure mode for sparse view data acquisition. Global PET ensemble root-mean-squares-error (RMSE) and local ensemble lesion activity error were used as quantitative evaluation metrics for PET image quality.With sparse view sampling, it is possible to greatly reduce the CT scan dose when it is primarily used for PET attenuation correction with little or no measureable effect on the PET image. For the four ultra-low dose levels

  9. Aberration corrected STEM of iron rhodium nanoislands

    Science.gov (United States)

    McLaren, M. J.; Hage, F. S.; Loving, M.; Ramasse, Q. M.; Lewis, L. H.; Marrows, C. H.; Brydson, R. M. D.

    2014-06-01

    Iron-rhodium (FeRh) nanoislands of equiatomic composition have been analysed using scanning transmission electron microscopy (STEM) electron energy loss spec-troscopy(EELS) and high angle annular dark field (HAADF) techniques. Previous magne-tometry results have lead to a hypothesis that at room temperature the core of the islands are antiferromagnetic while the shell has a small ferromagnetic signal. The causes of this effect are most likely to be a difference in composition at the edges or a strain on the island that stretches the lattice and forces the ferromagnetic transition. The results find, at the film-substrate interface, an iron-rich layer ~ 5 Å thick that could play a key role in affecting the magnetostructural transition around the interfacial region and account for the room temperature ferromagnetism.

  10. A study of the dosimetry of small field photon beams used in intensity-modulated radiation therapy in inhomogeneous media: Monte Carlo simulations and algorithm comparisons and corrections

    Science.gov (United States)

    Jones, Andrew Osler

    There is an increasing interest in the use of inhomogeneity corrections for lung, air, and bone in radiotherapy treatment planning. Traditionally, corrections based on physical density have been used. Modern algorithms use the electron density derived from CT images. Small fields are used in both conformal radiotherapy and IMRT, however their beam characteristics in inhomogeneous media have not been extensively studied. This work compares traditional and modern treatment planning algorithms to Monte Carlo simulations in and near low-density inhomogeneities. Field sizes ranging from 0.5 cm to 5 cm in diameter are projected onto a phantom containing inhomogeneities and depth dose curves are compared. Comparisons of the Dose Perturbation Factors (DPF) are presented as functions of density and field size. Dose Correction Factors (DCF), which scale the algorithms to the Monte Carlo data, are compared for each algorithm. Physical scaling algorithms such as Batho and Equivalent Pathlength (EPL) predict an increase in dose for small fields passing through lung tissue, where Monte Carlo simulations show a sharp dose drop. The physical model-based collapsed cone convolution (CCC) algorithm correctly predicts the dose drop, but does not accurately predict the magnitude. Because the model-based algorithms do not correctly account for the change in backscatter, the dose drop predicted by CCC occurs further downstream compared to that predicted by the Monte Carlo simulations. Beyond the tissue inhomogeneity all of the algorithms studied predict dose distributions in close agreement with Monte Carlo simulations. Dose-volume relationships are important in understanding the effects of radiation to the lung. Dose within the lung is affected by a complex function of beam energy, lung tissue density, and field size. Dose algorithms vary in their abilities to correctly predict the dose to the lung tissue. A thorough analysis of the effects of density, and field size on dose to the lung

  11. Solving the input data in error correction of optical fabrication by finite Fourier coefficient algorithm

    Institute of Scientific and Technical Information of China (English)

    CHENG; Haobo; SUN; Guozheng; FENG; Zhijing

    2006-01-01

    A free-form lens (FFL) is a special surface that is difficult to be fabricated. FFL are usually fabricated by computer-controlled optical surfacing (CCOS) technique. During CCOS, the material removal amount is determined by the unit removal function (URF) convoluting with the input data--the dwell time. When the removal amount and the URF are known, how to solve the input data involves the special algorithm--deconvolution. Usually, the input data are solved by virtue of low pass filter or iterative methods. However, an approximation solution would destroy the machining stability necessary to perform precisely CCOS. In this paper, to solve the input data, a new method that is based on the finite Fourier coefficient is put forward. It can give a continuous and accurate solution for fabricating choice. Several parameters are simulated, which influence the process of CCOS, and evaluating on the effect of the method is also carried out. Experimental results verify that this method is suitable for guiding the manufacturing of high precision FFL.

  12. Description and comparison of algorithms for correcting anisotropic magnification in cryo-EM images

    CERN Document Server

    Zhao, Jianhua; Benlekbir, Samir; Rubinstein, John L

    2015-01-01

    Single particle electron cryomicroscopy (cryo-EM) allows for structures of proteins and protein complexes to be determined from images of non-crystalline specimens. Cryo-EM data analysis requires electron microscope images of randomly oriented ice-embedded protein particles to be rotated and translated to allow for coherent averaging when calculating three-dimensional (3-D) structures. Rotation of 2-D images is usually done with the assumption that the magnification of the electron microscope is the same in all directions, a condition that has been found to be untrue with some electron microscopes when used with the settings necessary for cryo-EM with a direct detector device (DDD) camera (Grant and Grigorieff, in preparation). Correction of images by linear interpolation in real space has allowed high-resolution structures to be calculated from cryo-EM images for symmetric particles (Grant and Grigorieff, in preparation). Here we describe and compare a simple real space method and a somewhat more sophisticat...

  13. Impact of an intra-cycle motion correction algorithm on overall evaluability and diagnostic accuracy of computed tomography coronary angiography

    Energy Technology Data Exchange (ETDEWEB)

    Pontone, Gianluca; Bertella, Erika; Baggiano, Andrea; Mushtaq, Saima; Loguercio, Monica; Segurini, Chiara; Conte, Edoardo; Beltrama, Virginia; Annoni, Andrea; Formenti, Alberto; Petulla, Maria; Trabattoni, Daniela; Pepi, Mauro [Centro Cardiologico Monzino, IRCCS, Milan (Italy); Andreini, Daniele; Montorsi, Piero; Bartorelli, Antonio L. [Centro Cardiologico Monzino, IRCCS, Milan (Italy); University of Milan, Department of Cardiovascular Sciences and Community Health, Milan (Italy); Guaricci, Andrea I. [University of Foggia, Department of Cardiology, Foggia (Italy)

    2016-01-15

    The aim of this study was to evaluate the impact of a novel intra-cycle motion correction algorithm (MCA) on overall evaluability and diagnostic accuracy of cardiac computed tomography coronary angiography (CCT). From a cohort of 900 consecutive patients referred for CCT for suspected coronary artery disease (CAD), we enrolled 160 (18 %) patients (mean age 65.3 ± 11.7 years, 101 male) with at least one coronary segment classified as non-evaluable for motion artefacts. The CCT data sets were evaluated using a standard reconstruction algorithm (SRA) and MCA and compared in terms of subjective image quality, evaluability and diagnostic accuracy. The mean heart rate during the examination was 68.3 ± 9.4 bpm. The MCA showed a higher Likert score (3.1 ± 0.9 vs. 2.5 ± 1.1, p < 0.001) and evaluability (94%vs.79 %, p < 0.001) than the SRA. In a 45-patient subgroup studied by clinically indicated invasive coronary angiography, specificity, positive predictive value and accuracy were higher in MCA vs. SRA in segment-based and vessel-based models, respectively (87%vs.73 %, 50%vs.34 %, 85%vs.73 %, p < 0.001 and 62%vs.28 %, 66%vs.51 % and 75%vs.57 %, p < 0.001). In a patient-based model, MCA showed higher accuracy vs. SCA (93%vs.76 %, p < 0.05). MCA can significantly improve subjective image quality, overall evaluability and diagnostic accuracy of CCT. (orig.)

  14. SeaWiFS-derived products in the Baltic Sea: performance analysis of a simple atmospheric correction algorithm

    Directory of Open Access Journals (Sweden)

    Barbara Bulgarelli

    2003-12-01

    Full Text Available The accuracy analysis of an approximate atmospheric correction algorithm for the processing of SeaWiFS data has been investigated for the Baltic Sea. The analysis made use of theoretical radiances produced with the FEM radiative transfer code for representative atmosphere-water test cases. The study showed uncertainties in the determination of the aerosol optical thickness at 865 nm and of the Ångström exponent lower than ± 5% and ± 10%, respectively. These results were confirmed by the analysis of 59 match-ups between satellite-derived and in situ measurements for a site located in the central Baltic. Because of the relatively high yellow substance absorption, often combined with the slanted solar illumination, the retrieval of the water-leaving radiance in the blue part of the spectrum appeared to be highly degraded, to the extent that almost no correlation was found between retrieved and simulated values. Better results were obtained at the other wavelengths. The accuracy in the estimation of the remote sensing reflectance ratio R35 decreased with diminishing chlorophyll a concentration and increasing yellow substance absorption, ranging between ± 7% and ± 47%. The propagation of R35 uncertainties on chlorophyll a estimation was quantified. Keeping the same atmosphere-water conditions, the atmospheric correction scheme appeared sensitive to seasonal changes in the Sun zenith.

  15. SU-E-T-477: An Efficient Dose Correction Algorithm Accounting for Tissue Heterogeneities in LDR Brachytherapy

    Energy Technology Data Exchange (ETDEWEB)

    Mashouf, S; Lai, P [University of Toronto, Medical Biophysics Dept., Toronto, ON (Canada); Karotki, A; Keller, B; Beachey, D; Pignol, J [Sunnybrook Health Sciences Centre, Toronto, ON (Canada)

    2014-06-01

    Purpose: Seed brachytherapy is currently used for adjuvant radiotherapy of early stage prostate and breast cancer patients. The current standard for calculation of dose surrounding the brachytherapy seeds is based on American Association of Physicist in Medicine Task Group No. 43 (TG-43 formalism) which generates the dose in homogeneous water medium. Recently, AAPM Task Group No. 186 emphasized the importance of accounting for tissue heterogeneities. This can be done using Monte Carlo (MC) methods, but it requires knowing the source structure and tissue atomic composition accurately. In this work we describe an efficient analytical dose inhomogeneity correction algorithm implemented using MIM Symphony treatment planning platform to calculate dose distributions in heterogeneous media. Methods: An Inhomogeneity Correction Factor (ICF) is introduced as the ratio of absorbed dose in tissue to that in water medium. ICF is a function of tissue properties and independent of source structure. The ICF is extracted using CT images and the absorbed dose in tissue can then be calculated by multiplying the dose as calculated by the TG-43 formalism times ICF. To evaluate the methodology, we compared our results with Monte Carlo simulations as well as experiments in phantoms with known density and atomic compositions. Results: The dose distributions obtained through applying ICF to TG-43 protocol agreed very well with those of Monte Carlo simulations as well as experiments in all phantoms. In all cases, the mean relative error was reduced by at least 50% when ICF correction factor was applied to the TG-43 protocol. Conclusion: We have developed a new analytical dose calculation method which enables personalized dose calculations in heterogeneous media. The advantages over stochastic methods are computational efficiency and the ease of integration into clinical setting as detailed source structure and tissue segmentation are not needed. University of Toronto, Natural Sciences and

  16. Effect of snapshot freeze motion correction algorithm on image quality of coronary CT angiography without heart rate control

    International Nuclear Information System (INIS)

    Objective: To assess the effect of snapshot freeze (SSF) motion correction algorithm on the image quality of coronary CT angiography (CCTA). Methods: Thirty-one consecutive patients underwent coronary CTA without heart rate control. All of the CCTA images were reconstructed by the means of both standard (STD) and SSF motion correction. Image quality and interpretability of STD and SSF reconstructions were compared. CCTA images were interpreted with Likert 4-points score system by two experienced radiologists. The image qualities were assessed on per-artery and per-segment level, and interpretability was performed on per-segment, per-artery, and per-patient levels. Comparisons of variables were performed with paired Wilcoxon rank sum test and paired Chi-square test. Results: SSF reconstructions showed higher interpretability than STD reconstructions on per-patient [100.0% (31/31) vs 64.5% (20/31), χ2=9.09, P=0.002] and per-artery [100.0% (124/124) vs 83.9% (104/124), χ2=18.05, P=0.001] and per-segment level [99.0% (413/417) vs 89.2% (372/417), χ2=35.56, P=0.001]. Image qualities were higher with the use of SSF than STD reconstructions on LAD [3.3 ± 0.7 vs 2.9 ± 1.0, Z=2.70, P=0.007], LCX [3.1 ±0.8 vs 2.5 ± 1.1, Z=3.23, P=0.001] and RCA [3.3 ±0.6 vs 2.1 ± 0.9, Z=4.60, P=0.001], but they were similar on LM [3.9 ± 0.4 vs 3.7 ± 0.6, Z=1.89, P=0.059]. Image quality was higher with the use of SSF versus STD reconstructions on per-segment [3.5 ± 0.7 vs 3.0 ± 1.0, Z=10.31, P=0.001] level. Conclusions: The use of SSF motion correction algorithm improves image quality and interpretability of coronary CTA without heart rate control. (authors)

  17. Empirical evaluation of bias field correction algorithms for computer-aided detection of prostate cancer on T2w MRI

    Science.gov (United States)

    Viswanath, Satish; Palumbo, Daniel; Chappelow, Jonathan; Patel, Pratik; Bloch, B. Nicholas; Rofsky, Neil; Lenkinski, Robert; Genega, Elizabeth; Madabhushi, Anant

    2011-03-01

    In magnetic resonance imaging (MRI), intensity inhomogeneity refers to an acquisition artifact which introduces a non-linear variation in the signal intensities within the image. Intensity inhomogeneity is known to significantly affect computerized analysis of MRI data (such as automated segmentation or classification procedures), hence requiring the application of bias field correction (BFC) algorithms to account for this artifact. Quantitative evaluation of BFC schemes is typically performed using generalized intensity-based measures (percent coefficient of variation, %CV ) or information-theoretic measures (entropy). While some investigators have previously empirically compared BFC schemes in the context of different domains (using changes in %CV and entropy to quantify improvements), no consensus has emerged as to the best BFC scheme for any given application. The motivation for this work is that the choice of a BFC scheme for a given application should be dictated by application-specific measures rather than ad hoc measures such as entropy and %CV. In this paper, we have attempted to address the problem of determining an optimal BFC algorithm in the context of a computer-aided diagnosis (CAD) scheme for prostate cancer (CaP) detection from T2-weighted (T2w) MRI. One goal of this work is to identify a BFC algorithm that will maximize the CaP classification accuracy (measured in terms of the area under the ROC curve or AUC). A secondary aim of our work is to determine whether measures such as %CV and entropy are correlated with a classifier-based objective measure (AUC). Determining the presence or absence of these correlations is important to understand whether domain independent BFC performance measures such as %CV , entropy should be used to identify the optimal BFC scheme for any given application. In order to answer these questions, we quantitatively compared 3 different popular BFC algorithms on a cohort of 10 clinical 3 Tesla prostate T2w MRI datasets

  18. Effects of defect pixel correction algorithms for x-ray detectors on image quality in planar projection and volumetric CT data sets

    International Nuclear Information System (INIS)

    In this study we compared various defect pixel correction methods for reducing artifact appearance within projection images used for computed tomography (CT) reconstructions.Defect pixel correction algorithms were examined with respect to their artifact behaviour within planar projection images as well as in volumetric CT reconstructions. We investigated four algorithms: nearest neighbour, linear and adaptive linear interpolation, and a frequency-selective spectral-domain approach.To characterise the quality of each algorithm in planar image data, we inserted line defects of varying widths and orientations into images. The structure preservation of each algorithm was analysed by corrupting and correcting the image of a slit phantom pattern and by evaluating its line spread function (LSF). The noise preservation was assessed by interpolating corrupted flat images and estimating the noise power spectrum (NPS) of the interpolated region.For the volumetric investigations, we examined the structure and noise preservation within a structured aluminium foam, a mid-contrast cone-beam phantom and a homogeneous Polyurethane (PUR) cylinder.The frequency-selective algorithm showed the best structure and noise preservation for planar data of the correction methods tested. For volumetric data it still showed the best noise preservation, whereas the structure preservation was outperformed by the linear interpolation.The frequency-selective spectral-domain approach in the correction of line defects is recommended for planar image data, but its abilities within high-contrast volumes are restricted. In that case, the application of a simple linear interpolation might be the better choice to correct line defects within projection images used for CT. (paper)

  19. Dynamics of the eye's wave aberration.

    Science.gov (United States)

    Hofer, H; Artal, P; Singer, B; Aragón, J L; Williams, D R

    2001-03-01

    It is well known that the eye's optics exhibit temporal instability in the form of microfluctuations in focus; however, almost nothing is known of the temporal properties of the eye's other aberrations. We constructed a real-time Hartmann-Shack (HS) wave-front sensor to measure these dynamics at frequencies as high as 60 Hz. To reduce spatial inhomogeneities in the short-exposure HS images, we used a low-coherence source and a scanning system. HS images were collected on three normal subjects with natural and paralyzed accommodation. Average temporal power spectra were computed for the wave-front rms, the Seidel aberrations, and each of 32 Zernike coefficients. The results indicate the presence of fluctuations in all of the eye's aberration, not just defocus. Fluctuations in higher-order aberrations share similar spectra and bandwidths both within and between subjects, dropping at a rate of approximately 4 dB per octave in temporal frequency. The spectrum shape for higher-order aberrations is generally different from that for microfluctuations of accommodation. The origin of these measured fluctuations is not known, and both corneal/lenticular and retinal causes are considered. Under the assumption that they are purely corneal or lenticular, calculations suggest that a perfect adaptive optics system with a closed-loop bandwidth of 1-2 Hz could correct these aberrations well enough to achieve diffraction-limited imaging over a dilated pupil. PMID:11265680

  20. DEFLATE Compression Algorithm Corrects for Overestimation of Phylogenetic Diversity by Grantham Approach to Single-Nucleotide Polymorphism Classification

    Directory of Open Access Journals (Sweden)

    Arran Schlosberg

    2014-05-01

    Full Text Available Improvements in speed and cost of genome sequencing are resulting in increasing numbers of novel non-synonymous single nucleotide polymorphisms (nsSNPs in genes known to be associated with disease. The large number of nsSNPs makes laboratory-based classification infeasible and familial co-segregation with disease is not always possible. In-silico methods for classification or triage are thus utilised. A popular tool based on multiple-species sequence alignments (MSAs and work by Grantham, Align-GVGD, has been shown to underestimate deleterious effects, particularly as sequence numbers increase. We utilised the DEFLATE compression algorithm to account for expected variation across a number of species. With the adjusted Grantham measure we derived a means of quantitatively clustering known neutral and deleterious nsSNPs from the same gene; this was then used to assign novel variants to the most appropriate cluster as a means of binary classification. Scaling of clusters allows for inter-gene comparison of variants through a single pathogenicity score. The approach improves upon the classification accuracy of Align-GVGD while correcting for sensitivity to large MSAs. Open-source code and a web server are made available at https://github.com/aschlosberg/CompressGV.

  1. A two-dimensional, finite-element, flux-corrected transport algorithm for the solution of gas discharge problems

    Science.gov (United States)

    Georghiou, G. E.; Morrow, R.; Metaxas, A. C.

    2000-10-01

    An improved finite-element flux-corrected transport (FE-FCT) scheme, which was demonstrated in one dimension by the authors, is now extended to two dimensions and applied to gas discharge problems. The low-order positive ripple-free scheme, required to produce a FCT algorithm, is obtained by introducing diffusion to the high-order scheme (two-step Taylor-Galerkin). A self-adjusting variable diffusion coefficient is introduced, which reduces the high-order scheme to the equivalent of the upwind difference scheme, but without the complexities of an upwind scheme in a finite-element setting. Results are presented which show that the high-order scheme reduces to the equivalent of upwinding when the new diffusion coefficient is used. The proposed FCT scheme is shown to give similar results in comparison to a finite-difference time-split FCT code developed by Boris and Book. Finally, the new method is applied for the first time to a streamer propagation problem in its two-dimensional form.

  2. Brachytherapy heterogeneity correction algorithm

    OpenAIRE

    Hueso González, Fernando

    2011-01-01

    El objetivo de este trabajo de investigación es el estudio de la influencia de heterogeneidades de los tejidos en la dosimetría de braquiterapia. En concreto, hemos desarrollado un algoritmo que tiene en cuenta las calcificaciones localizadas dentro de la próstata y corrige la dosis de referencia en agua. Este algoritmo está basado en un modelo analítico y es aplicable a Sistemas de Planificación del Tratamiento (TPS) comerciales. El modelo analítico tiene un fundamento teórico consistente...

  3. Alteration of introns in a hyaluronan synthase 1 (HAS1 minigene convert Pre-mRNA [corrected] splicing to the aberrant pattern in multiple myeloma (MM: MM patients harbor similar changes.

    Directory of Open Access Journals (Sweden)

    Jitra Kriangkum

    Full Text Available Aberrant pre-mRNA splice variants of hyaluronan synthase 1 (HAS1 have been identified in malignant cells from cancer patients. Bioinformatic analysis suggests that intronic sequence changes can underlie aberrant splicing. Deletions and mutations were introduced into HAS1 minigene constructs to identify regions that can influence aberrant intronic splicing, comparing the splicing pattern in transfectants with that in multiple myeloma (MM patients. Introduced genetic variations in introns 3 and 4 of HAS1 as shown here can promote aberrant splicing of the type detected in malignant cells from MM patients. HAS1Vd is a novel intronic splice variant first identified here. HAS1Vb, an intronic splice variant previously identified in patients, skips exon 4 and utilizes the same intron 4 alternative 3'splice site as HAS1Vd. For transfected constructs with unaltered introns 3 and 4, HAS1Vd transcripts are readily detectable, frequently to the exclusion of HAS1Vb. In contrast, in MM patients, HAS1Vb is more frequent than HAS1Vd. In the HAS1 minigene, combining deletion in intron 4 with mutations in intron 3 leads to a shift from HAS1Vd expression to HAS1Vb expression. The upregulation of aberrant splicing, exemplified here by the expression of HAS1Vb, is shown here to be influenced by multiple genetic changes in intronic sequences. For HAS1Vb, this includes enhanced exon 4 skipping and increased usage of alternative 3' splice sites. Thus, the combination of introduced mutations in HAS1 intron3 with introduced deletions in HAS1 intron 4 promoted a shift to an aberrant splicing pattern previously shown to be clinically significant. Most MM patients harbor genetic variations in intron 4, and as shown here, nearly half harbor recurrent mutations in HAS1 intron 3. Our work suggests that aberrant intronic HAS1 splicing in MM patients may rely on intronic HAS1 deletions and mutations that are frequent in MM patients but absent from healthy donors.

  4. Differences in aerosol absorption Ångström exponents between correction algorithms for a particle soot absorption photometer measured on the South African Highveld

    Science.gov (United States)

    Backman, J.; Virkkula, A.; Vakkari, V.; Beukes, J. P.; Van Zyl, P. G.; Josipovic, M.; Piketh, S.; Tiitta, P.; Chiloane, K.; Petäjä, T.; Kulmala, M.; Laakso, L.

    2014-12-01

    Absorption Ångström exponents (AAEs) calculated from filter-based absorption measurements are often used to give information on the origin of the ambient aerosol, for example, to distinguish between urban pollution and biomass burning aerosol. Filter-based absorption measurements are widely used and are common at aerosol monitoring stations globally. Several correction algorithms are used to account for artefacts associated with filter-based absorption techniques. These algorithms are of profound importance when determining the absolute amount of absorption by the aerosol. However, this study shows that there are substantial differences between the AAEs calculated from these corrections. Depending on the used correction, AAEs can change by as much as 46%. The study also highlights that the difference between AAEs calculated using different corrections can lead to conflicting conclusions on the type of aerosol when using the same data set. The AAE ranged between 1.17 for non-corrected data to 1.96 for the correction that gave the greatest values. Furthermore, the study implies that the AAEs reported for a site depend on at which filter transmittance the filter is changed. In this work, the AAEs were calculated from data measured with a three-wavelength particle soot absorption photometer (PSAP) at Elandsfontein on the South African Highveld for 23 months. The sample air of the PSAP was diluted to prolong filter change intervals, by a factor of 15. The correlation coefficient between the dilution-corrected PSAP and a non-diluted Multi-Angle Absorption Photometer (MAAP) was 0.9. Thus, the study also shows that the applicability of the PSAP can be extended to remote sites that are not often visited or suffer from high levels of pollution.

  5. A dose calculation algorithm with correction for proton-nucleus interactions in non-water materials for proton radiotherapy treatment planning

    Science.gov (United States)

    Inaniwa, T.; Kanematsu, N.; Sato, S.; Kohno, R.

    2016-01-01

    In treatment planning for proton radiotherapy, the dose measured in water is applied to the patient dose calculation with density scaling by stopping power ratio {ρ\\text{S}} . Since the body tissues are chemically different from water, this approximation may cause dose calculation errors, especially due to differences in nuclear interactions. We proposed and validated an algorithm for correcting these errors. The dose in water is decomposed into three constituents according to the physical interactions of protons in water: the dose from primary protons continuously slowing down by electromagnetic interactions, the dose from protons scattered by elastic and/or inelastic interactions, and the dose resulting from nonelastic interactions. The proportions of the three dose constituents differ between body tissues and water. We determine correction factors for the proportion of dose constituents with Monte Carlo simulations in various standard body tissues, and formulated them as functions of their {ρ\\text{S}} for patient dose calculation. The influence of nuclear interactions on dose was assessed by comparing the Monte Carlo simulated dose and the uncorrected dose in common phantom materials. The influence around the Bragg peak amounted to  -6% for polytetrafluoroethylene and 0.3% for polyethylene. The validity of the correction method was confirmed by comparing the simulated and corrected doses in the materials. The deviation was below 0.8% for all materials. The accuracy of the correction factors derived with Monte Carlo simulations was separately verified through irradiation experiments with a 235 MeV proton beam using common phantom materials. The corrected doses agreed with the measurements within 0.4% for all materials except graphite. The influence on tumor dose was assessed in a prostate case. The dose reduction in the tumor was below 0.5%. Our results verify that this algorithm is practical and accurate for proton radiotherapy treatment planning, and

  6. Fast algorithms for generating binary holograms

    CERN Document Server

    Stuart, Dustin; Kuhn, Axel

    2014-01-01

    We describe three algorithms for generating binary-valued holograms. Our methods are optimised for producing large arrays of tightly focussed optical tweezers for trapping particles. Binary-valued holograms allow us to use a digital mirror device (DMD) as the display element, which is much faster than other alternatives. We describe how our binary amplitude holograms can be used to correct for phase errors caused by optical aberrations. Furthermore, we compare the speed and accuracy of the algorithms for both periodic and arbitrary arrangements of traps, which allows one to choose the ideal scheme depending on the circumstances.

  7. Validation of Correction Algorithms for Near-IR Analysis of Human Milk in an Independent Sample Set-Effect of Pasteurization.

    Science.gov (United States)

    Kotrri, Gynter; Fusch, Gerhard; Kwan, Celia; Choi, Dasol; Choi, Arum; Al Kafi, Nisreen; Rochow, Niels; Fusch, Christoph

    2016-03-01

    Commercial infrared (IR) milk analyzers are being increasingly used in research settings for the macronutrient measurement of breast milk (BM) prior to its target fortification. These devices, however, may not provide reliable measurement if not properly calibrated. In the current study, we tested a correction algorithm for a Near-IR milk analyzer (Unity SpectraStar, Brookfield, CT, USA) for fat and protein measurements, and examined the effect of pasteurization on the IR matrix and the stability of fat, protein, and lactose. Measurement values generated through Near-IR analysis were compared against those obtained through chemical reference methods to test the correction algorithm for the Near-IR milk analyzer. Macronutrient levels were compared between unpasteurized and pasteurized milk samples to determine the effect of pasteurization on macronutrient stability. The correction algorithm generated for our device was found to be valid for unpasteurized and pasteurized BM. Pasteurization had no effect on the macronutrient levels and the IR matrix of BM. These results show that fat and protein content can be accurately measured and monitored for unpasteurized and pasteurized BM. Of additional importance is the implication that donated human milk, generally low in protein content, has the potential to be target fortified. PMID:26927169

  8. Differences in aerosol absorption Ångström exponents between correction algorithms for particle soot absorption photometer measured on South African Highveld

    Directory of Open Access Journals (Sweden)

    J. Backman

    2014-09-01

    Full Text Available Absorption Ångstrom exponents (AAE calculated from filter-based absorption measurements are often used to give information on the origin of the ambient aerosol, for example to distinguish between urban pollution and biomass burning aerosol. Filter-based absorption measurements are a widely used method and are commonly used at aerosol monitoring stations globally. Several correction algorithms are used to account for the artifacts associated with filter-based absorption techniques. These algorithms are of profound importance when determining the absolute amount of absorption by the aerosol. However, this study shows that there are significant differences between the AAEs calculated from these corrections. The study also shows that the difference between AAEs calculated using different corrections can lead to conflicting conclusions on the type of aerosol for the same data set. In this work the AAEs were calculated from data measured with a three-wavelength Particle Soot Absorption Photometer (PSAP at Elandsfontein on deployed on the South African Highveld for 23 months. The sample air of the PSAP was diluted to prolong filter change intervals. The dilution-corrected PSAP showed a good agreement with a non-diluted MAAP. Thus, the study also shows that the applicability of the PSAP can be extended to remote sites are not often visited or suffer from high levels of pollution.

  9. Differences in aerosol absorption Ångström exponents between correction algorithms for particle soot absorption photometer measured on South African Highveld

    Science.gov (United States)

    Backman, J.; Virkkula, A.; Vakkari, V.; Beukes, J. P.; Van Zyl, P.; Josipovic, M.; Piketh, S.; Tiitta, P.; Chiloane, K.; Petäjä, T.; Kulmala, M.; Laakso, L.

    2014-09-01

    Absorption Ångstrom exponents (AAE) calculated from filter-based absorption measurements are often used to give information on the origin of the ambient aerosol, for example to distinguish between urban pollution and biomass burning aerosol. Filter-based absorption measurements are a widely used method and are commonly used at aerosol monitoring stations globally. Several correction algorithms are used to account for the artifacts associated with filter-based absorption techniques. These algorithms are of profound importance when determining the absolute amount of absorption by the aerosol. However, this study shows that there are significant differences between the AAEs calculated from these corrections. The study also shows that the difference between AAEs calculated using different corrections can lead to conflicting conclusions on the type of aerosol for the same data set. In this work the AAEs were calculated from data measured with a three-wavelength Particle Soot Absorption Photometer (PSAP) at Elandsfontein on deployed on the South African Highveld for 23 months. The sample air of the PSAP was diluted to prolong filter change intervals. The dilution-corrected PSAP showed a good agreement with a non-diluted MAAP. Thus, the study also shows that the applicability of the PSAP can be extended to remote sites are not often visited or suffer from high levels of pollution.

  10. Ocular aberrations after wavefront optimized LASIK for myopia

    Directory of Open Access Journals (Sweden)

    Padmanabhan Prema

    2010-01-01

    Full Text Available Purpose: To study the change in ocular aberrations after wavefront optimized (WFO laser in situ keratomileusis ( Lasik for correction of myopia and to analyze causative factors that may influence them. Materials and Methods: This was a prospective case series. WFO Lasik was performed for the correction of myopia, using the hansatome (Bausch and Lomb microkeratome to create the flap and the Allegretto laser (Wavelight Technologie to perform the ablation. The Allegretto wave analyser (Tscherning-type measured the ocular aberrations prior to Lasik , one month and six months postoperatively. Results: The mean age of the 59 patients included in the study was 25±5.64 years and the mean spherical equivalent of the 117 eyes that underwent Lasik0 was -5.33±1.22 preoperatively and -0.21±0.38 postoperatively. Hundred and two eyes of 117 (87% achieved uncorrected visual acuity (UCVA of 20/20 or better after WFO Lasik and 104 of 117 eyes (89% were within ±0.5D of the attempted refractive correction. There was a 1.96-fold increase in total root-mean-square of higher order aberrations. Induced changes in seven of the 22 higher order Zernike terms showed a significant linear correlation with the refractive correction attempted. Larger ablation zones induced less spherical aberration. Conclusion: In spite of an excellent visual outcome, WFO Lasik induces significant higher order aberrations. Large ablation zones reduce the induction of spherical aberration.

  11. Multi-actuator adaptive lens for wavefront correction in optical coherence tomography and two-photon excitation fluorescence microscopy (Conference Presentation)

    Science.gov (United States)

    Bonora, Stefano; Lee, Sujin; Jian, Yifan; Cua, Michelle; Pugh, Edward N.; Zawadzki, Robert J.; Sarunic, Marinko V.

    2016-03-01

    We present a new type of adaptive lens with 18 actuators that can correct up the 4th order of aberration. The Multi-actuator Adaptive Lens (M-AL) can guarantee a good level of aberration correction for many applications and, with respect to deformable mirror, it allows the realization of more compact and simple optical systems. The adaptive lens is based on the use of piezoelectric actuators and, without any obstruction or electrodes in the clear aperture, can guarantee a fast response time, in the order of about 10ms. The clear aperture of the M-AL allows its use in "classical" Adaptive Optics configuration together with a wavefront sensor. To introduce a further simplification to the optical system design we show that the adaptive lens can be also driven with a wavefront sensorless control algorithm during in vivo optical coherence tomography of the human retina and for two-photon excitation fluorescence microscopy. In the experimental setup we used two aberration correcting devices a commercial adaptive lens (AL) with a high dynamic range to correct for defocus and the Multi-actuator Adaptive Lens (M-AL) to correct for the Zernike aberrations up to the 4th order. Experimental results show that the ocular aberrations of human eyes can be successfully corrected with our M-AL for pupils of 5mm and that retinal cones can be readily imaged.

  12. Development of rubber mixing process mathematical model and synthesis of control correction algorithm by process temperature mode using an artificial neural network

    Directory of Open Access Journals (Sweden)

    V. S. Kudryashov

    2016-01-01

    Full Text Available The article is devoted to the development of a correction control algorithm by temperature mode of a periodic rubber mixing process for JSC "Voronezh tire plant". The algorithm is designed to perform in the main controller a section of rubber mixing Siemens S7 CPU319F-3 PN/DP, which forms tasks for the local temperature controllers HESCH HE086 and Jumo dTRON304, operating by tempering stations. To compile the algorithm was performed a systematic analysis of rubber mixing process as an object of control and was developed a mathematical model of the process based on the heat balance equations describing the processes of heat transfer through the walls of technological devices, the change of coolant temperature and the temperature of the rubber compound mixing until discharge from the mixer chamber. Due to the complexity and nonlinearity of the control object – Rubber mixers and the availability of methods and a wide experience of this device control in an industrial environment, a correction algorithm is implemented on the basis of an artificial single-layer neural network and it provides the correction of tasks for local controllers on the cooling water temperature and air temperature in the workshop, which may vary considerably depending on the time of the year, and during prolonged operation of the equipment or its downtime. Tempering stations control is carried out by changing the flow of cold water from the cooler and on/off control of the heating elements. The analysis of the model experiments results and practical research at the main controller programming in the STEP 7 environment at the enterprise showed a decrease in the mixing time for different types of rubbers by reducing of heat transfer process control error.

  13. Anisoplanatism in adaptive optics systems due to pupil aberrations

    Energy Technology Data Exchange (ETDEWEB)

    Bauman, B

    2005-08-01

    Adaptive optics systems typically include an optical relay that simultaneously images the science field to be corrected and also a set of pupil planes conjugate to the deformable mirror of the system. Often, in the optical spaces where DM's are placed, the pupils are aberrated, leading to a displacement and/or distortion of the pupil that varies according to field position--producing a type of anisoplanatism, i.e., a degradation of the AO correction with field angle. The pupil aberration phenomenon is described and expressed in terms of Seidel aberrations. An expression for anisoplanatism as a function of pupil distortion is derived, an example of an off-axis parabola is given, and a convenient method for controlling pupil-aberration-generated anisoplanatism is proposed.

  14. Correction of Faulty Sensors in Phased Array Radars Using Symmetrical Sensor Failure Technique and Cultural Algorithm with Differential Evolution

    OpenAIRE

    Khan, S. U.; I.M. Qureshi; F. Zaman; B. Shoaib; A. Naveed; Basit, A.

    2014-01-01

    Three issues regarding sensor failure at any position in the antenna array are discussed. We assume that sensor position is known. The issues include raise in sidelobe levels, displacement of nulls from their original positions, and diminishing of null depth. The required null depth is achieved by making the weight of symmetrical complement sensor passive. A hybrid method based on memetic computing algorithm is proposed. The hybrid method combines the cultural algorithm with differential evol...

  15. A fast marching method based back projection algorithm for photoacoustic tomography in heterogeneous media

    CERN Document Server

    Wang, Tianren

    2015-01-01

    This paper presents a numerical study on a fast marching method based back projection reconstruction algorithm for photoacoustic tomography in heterogeneous media. Transcranial imaging is used here as a case study. To correct for the phase aberration from the heterogeneity (i.e., skull), the fast marching method is adopted to compute the phase delay based on the known speed of sound distribution, and the phase delay is taken into account by the back projection algorithm for more accurate reconstructions. It is shown that the proposed algorithm is more accurate than the conventional back projection algorithm, but slightly less accurate than the time reversal algorithm particularly in the area close to the skull. However, the image reconstruction time for the proposed algorithm can be as little as 124 ms when implemented by a GPU (512 sensors, 21323 pixels reconstructed), which is two orders of magnitude faster than the time reversal reconstruction. The proposed algorithm, therefore, not only corrects for the p...

  16. Aberrations of the cathode objective lens up to fifth order

    Energy Technology Data Exchange (ETDEWEB)

    Tromp, R.M., E-mail: rtromp@us.ibm.com [Thomas J. Watson Research Center, IBM Research Division, 1101 Kitchawan Road, P.O. Box 218, Yorktown Heights, NY 10598 (United States); Leiden University, Kamerlingh Onnes Laboratorium, P.O. Box 9504, NL-2300 RA Leiden (Netherlands); Wan, W. [Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 80R0114, Berkeley, CA 94720 (United States); Schramm, S.M. [Leiden University, Kamerlingh Onnes Laboratorium, P.O. Box 9504, NL-2300 RA Leiden (Netherlands)

    2012-08-15

    In this paper we discuss a topic that was close to Prof. Gertrude Rempfer s interests for many years. On this occasion of her 100th birthday, we remember and honor Gertrude for her many outstanding contributions, and for the inspiring example that she set. We derive theoretical expressions for the aberration coefficients of the uniform electrostatic field up to 5th order and compare these with raytracing calculations for the cathode lens used in Low Energy Electron Microscopy and Photo Electron Emission Microscopy experiments. These higher order aberration coefficients are of interest for aberration corrected experiments in which chromatic (C{sub c}) and spherical (C{sub 3}) aberrations of the microscope are set to zero. The theoretical predictions are in good agreement with the results of raytracing. Calculations of image resolution using the Contrast Transfer Function method show that sub-nanometer resolution is achievable in an aberration corrected LEEM system. -- Highlights: Black-Right-Pointing-Pointer A theory is presented for the aberrations of the uniform electrostatic field up to fifth order. Black-Right-Pointing-Pointer Such aberrations are important for advanced LEEM and PEEM instruments. Black-Right-Pointing-Pointer Good agreement between theory and raytracing results for a full cathode objective lens. Black-Right-Pointing-Pointer Contrast Transfer Function calculations predict that spatial resolution below 1 nm is achievable.

  17. Study of residual aberration for non-imaging focusing heliostat

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Y.T.; Chong, K.K.; Lim, B.H.; Lim, C.S. [Institute of Energy and Environment, Malaysia University of Science and Technology, No. 17, Jalan SS7/26, Kelana Jaya, 47301 Petaling Jaya, Selangor (Malaysia)

    2003-08-01

    Instead of using a specific focusing geometry, a non-imaging focusing heliostat has no fixed geometry but is composed of many small movable element mirrors that can be manoeuvred to eliminate the first-order aberration. Following our previous publication on the principle of non-imaging focusing heliostat, this paper further explores higher order residual aberration that limits the size of the focusing spot. The residual aberration can be partially corrected by offsetting the pivot point of mirrors and pre-setting the tilting angles of mirrors.

  18. 校正激光光束指向漂移的算法研究%Research of algorithm to correct direction drifts of laser beam

    Institute of Scientific and Technical Information of China (English)

    张丽霞; 林妩媚; 廖志杰; 王瑞林

    2012-01-01

    In order to obtain stable laser beam, random deviations of light beams should be corrected. Taking the progress of adjusting direction drifts of pulse laser beam with fast steering mirrors in the beam delivery system as an example, an algorithm based on moving average ( MA) correction mechanism was used to simulate the correction outcomes with or without ground jitters. MA and moving standard deviation (MSD) are used to evaluate the correction effects. The results indicate that this algorithm can control the position excursions on the plane of beam delivery system caused by the direction drifts of laser beam effectively, and the MA corrected has a big jump between n ~1n pulses, for example, the optimal MA can be reduced to r-1/2 times (n is, pulse numbers in a window). At the same time, there is a sudden decline in MSD between n- ~2n pulses, and soon afterwards, MSD is going to be sticking. Meanwhile, the drifts can be restrained while loading the ground jitters, and the dropping amplitude is bigger than without the ground jitters. The results show thai the key of applications lies in construction of the appropriate corrections. What is more, this algorithm which is practical can achieve real-time control of direction drifts.%为了获得稳定的激光光束,需要对其随机漂移进行校正.以光束传递系统中快速反射镜校正脉冲激光器自身指向漂移的过程为例,采用一种基于移动平均值校正原理的算法,对加载地面抖动前后的校正效果进行了仿真模拟.仿真结果显示,该算法可以使指向漂移经过长距离传输后引入的位置偏移显著降低;校正后的移动平均值相对于校正前的有较大降幅,最优处约降至原来的n -1/2(n为一个窗口内的脉冲数);校正后的移动标准偏差值也明显下降.结果表明,该算法的关键在于提出合适的补偿量,具有实用性,可以实现对激光光束指向漂移的闭环实时校正.

  19. Combined Nonuniformity Correction Algorithm of Infrared Focal Plane Arrays%红外焦平面联合非均匀性校正算法

    Institute of Scientific and Technical Information of China (English)

    洪闻青; 杨南生; 王晓东; 苏俊波; 苏兰; 胡志斌

    2011-01-01

    分别分析了红外焦平面阵列(IRFPA)基于定标的非均匀性校正(NUC)算法和基于场景的NUC算法的优势和问题.在此基础上提出了联合NUC算法,其中利用基于定标的两点校正法来初步消除探测器的非均匀性,然后再采用基于场景的时域高通校正法和新型自适应滤波校正法来抑制探测器非均匀性参数漂移的影响,同时减弱系统噪声对成像质量的破坏.实验结果表明,与两点法、时域高通法以及传统自适应滤波法等具有较大工程应用价值的NUC算法相比,联合NUC算法具有稳定而且性能更为优良的校正效果.%The advantages and disadvantages in nonuniformity correction (NUC) algorithms based on calibration and scene of infrared focal plane arrays (IRFPA) are analysed separately. The combined NUC algorithm is presented.Two-point NUC algorithm based on calibration is adopted to remove the nonuniformity of the detector simply. The influences of detectors' NUC parameters which will change with time are weakened by using the scene-based temporal high-pass filter algorithm and new-style adaptive filter algorithm. The disadvantages for image quality introduced by ynoises are weakened too. The experimental results show that the combined NUC algorithm is more stable and better than some NUC algorithms with great value in project applications, such as two point NUC algorithm, temporal highpass filter NUC algorithm and former adaptive filter NUC algorithm.

  20. Correction of Faulty Sensors in Phased Array Radars Using Symmetrical Sensor Failure Technique and Cultural Algorithm with Differential Evolution

    Directory of Open Access Journals (Sweden)

    S. U. Khan

    2014-01-01

    Full Text Available Three issues regarding sensor failure at any position in the antenna array are discussed. We assume that sensor position is known. The issues include raise in sidelobe levels, displacement of nulls from their original positions, and diminishing of null depth. The required null depth is achieved by making the weight of symmetrical complement sensor passive. A hybrid method based on memetic computing algorithm is proposed. The hybrid method combines the cultural algorithm with differential evolution (CADE which is used for the reduction of sidelobe levels and placement of nulls at their original positions. Fitness function is used to minimize the error between the desired and estimated beam patterns along with null constraints. Simulation results for various scenarios have been given to exhibit the validity and performance of the proposed algorithm.

  1. 基于人工智能与改进PID的纠偏算法的研究%Study on Correction Algorithm Based on Artificial Intelligence and Improved PID

    Institute of Scientific and Technical Information of China (English)

    张卓; 贾晨辉

    2011-01-01

    在分析常规PID控制原理和PID主参数作用的基础上,提出一种人工智能PID算法,并将该算法用于带材纠偏控制,根据偏差的程度自整定PID控制参数,有效地解决了控制过程中存在的矛盾.%A PID artificial intelligence algorithm was presented based on the analyses of conventional PID control theory and the roles of the main parameters of the PID.The algorithm was used to correct the position deviation of strip.According to the degree of deviation, PID control parameters were self-tuned.The Contradictions existed in control process are effectively resolved.

  2. Investigations on control algorithm of steady-state cornering and control strategy for dynamical correction in a steer-by-wire system

    Institute of Scientific and Technical Information of China (English)

    Ying XU; Chang-fu ZONG; Hsiao-hsiang NA; Lei LIU

    2009-01-01

    To improve the handling performance of a steer-by-wire (SBW) vehicle, a series of control logics are proposed. Firstly,an algorithm for enhancing the maneuvering in steady-state cornering is presented. On this basis, two categories of control strategies are used to dynamically correct and compensate the transient state steering responses and vehicle behaviors. Simulator tests including subjective evaluations and virtual field tests are both conducted to make comprehensive investigations on the series of control logics. The subjective evaluations demonstrate that the SBW vehicle with a specifically selected value of steering sensitivity tends to be more desirable for driving than a conventional one in which a fixed steering ratio exists. The virtual field tests indicate that the control strategies for dynamical correction and compensation could effectively improve the handling performances of an SBW vehicle by reducing the work load of drivers, enhancing the track-holding performance, and improving steering response properties.

  3. Identification of candidate driver genes in common focal chromosomal aberrations of microsatellite stable colorectal cancer.

    Directory of Open Access Journals (Sweden)

    George J Burghel

    Full Text Available Colorectal cancer (CRC is a leading cause of cancer deaths worldwide. Chromosomal instability (CIN is a major driving force of microsatellite stable (MSS sporadic CRC. CIN tumours are characterised by a large number of somatic chromosomal copy number aberrations (SCNA that frequently affect oncogenes and tumour suppressor genes. The main aim of this work was to identify novel candidate CRC driver genes affected by recurrent and focal SCNA. High resolution genome-wide comparative genome hybridisation (CGH arrays were used to compare tumour and normal DNA for 53 sporadic CRC cases. Context corrected common aberration (COCA analysis and custom algorithms identified 64 deletions and 32 gains of focal minimal common regions (FMCR at high frequency (>10%. Comparison of these FMCR with published genomic profiles from CRC revealed common overlap (42.2% of deletions and 34.4% of copy gains. Pathway analysis showed that apoptosis and p53 signalling pathways were commonly affected by deleted FMCR, and MAPK and potassium channel pathways by gains of FMCR. Candidate tumour suppressor genes in deleted FMCR included RASSF3, IFNAR1, IFNAR2 and NFKBIA and candidate oncogenes in gained FMCR included PRDM16, TNS1, RPA3 and KCNMA1. In conclusion, this study confirms some previously identified aberrations in MSS CRC and provides in silico evidence for some novel candidate driver genes.

  4. Identification of Candidate Driver Genes in Common Focal Chromosomal Aberrations of Microsatellite Stable Colorectal Cancer

    Science.gov (United States)

    Burghel, George J.; Lin, Wei-Yu; Whitehouse, Helen; Brock, Ian; Hammond, David; Bury, Jonathan; Stephenson, Yvonne; George, Rina; Cox, Angela

    2013-01-01

    Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. Chromosomal instability (CIN) is a major driving force of microsatellite stable (MSS) sporadic CRC. CIN tumours are characterised by a large number of somatic chromosomal copy number aberrations (SCNA) that frequently affect oncogenes and tumour suppressor genes. The main aim of this work was to identify novel candidate CRC driver genes affected by recurrent and focal SCNA. High resolution genome-wide comparative genome hybridisation (CGH) arrays were used to compare tumour and normal DNA for 53 sporadic CRC cases. Context corrected common aberration (COCA) analysis and custom algorithms identified 64 deletions and 32 gains of focal minimal common regions (FMCR) at high frequency (>10%). Comparison of these FMCR with published genomic profiles from CRC revealed common overlap (42.2% of deletions and 34.4% of copy gains). Pathway analysis showed that apoptosis and p53 signalling pathways were commonly affected by deleted FMCR, and MAPK and potassium channel pathways by gains of FMCR. Candidate tumour suppressor genes in deleted FMCR included RASSF3, IFNAR1, IFNAR2 and NFKBIA and candidate oncogenes in gained FMCR included PRDM16, TNS1, RPA3 and KCNMA1. In conclusion, this study confirms some previously identified aberrations in MSS CRC and provides in silico evidence for some novel candidate driver genes. PMID:24367615

  5. Analysis of vegetation by the application of a physically-based atmospheric correction algorithm to OLI data: a case study of Leonessa Municipality, Italy

    Science.gov (United States)

    Mei, Alessandro; Manzo, Ciro; Petracchini, Francesco; Bassani, Cristiana

    2016-04-01

    Remote sensing techniques allow to estimate vegetation parameters related to large areas for forest health evaluation and biomass estimation. Moreover, the parametrization of specific indices such as Normalized Difference Vegetation Index (NDVI) allows to study biogeochemical cycles and radiative energy transfer processes between soil/vegetation and atmosphere. This paper focuses on the evaluation of vegetation cover analysis in Leonessa Municipality, Latium Region (Italy) by the use of 2015 Landsat 8 applying the OLI@CRI (OLI ATmospherically Corrected Reflectance Imagery) algorithm developed following the procedure described in Bassani et al. 2015. The OLI@CRI is based on 6SV radiative transfer model (Kotchenova et al., 2006) ables to simulate the radiative field in the atmosphere-earth coupled system. NDVI was derived from the OLI corrected image. This index, widely used for biomass estimation and vegetation analysis cover, considers the sensor channels falling in the near infrared and red spectral regions which are sensitive to chlorophyll absorption and cell structure. The retrieved product was then spatially resampled at MODIS image resolution and then validated by the NDVI of MODIS considered as reference. The physically-based OLI@CRI algorithm also provides the incident solar radiation at ground at the acquisition time by 6SV simulation. Thus, the OLI@CRI algorithm completes the remote sensing dataset required for a comprehensive analysis of the sub-regional biomass production by using data of the new generation remote sensing sensor and an atmospheric radiative transfer model. If the OLI@CRI algorithm is applied to a temporal series of OLI data, the influence of the solar radiation on the above-ground vegetation can be analysed as well as vegetation index variation.

  6. An algorithm for estimation and correction of anisotropic magnification distortion of cryo-EM images without need of pre-calibration.

    Science.gov (United States)

    Yu, Guimei; Li, Kunpeng; Liu, Yue; Chen, Zhenguo; Wang, Zhiqing; Yan, Rui; Klose, Thomas; Tang, Liang; Jiang, Wen

    2016-08-01

    Anisotropic magnification distortion of TEM images (mainly the elliptic distortion) has been recently found as a potential resolution-limiting factor in single particle 3-D reconstruction. Elliptic distortions of ∼1-3% have been reported for multiple microscopes under low magnification settings (e.g., 18,000×), which significantly limited the achievable resolution of single particle 3-D reconstruction, especially for large particles. Here we report a generic algorithm that formulates the distortion correction problem as a generalized 2-D alignment task and estimates the distortion parameters directly from the particle images. Unlike the present pre-calibration methods, our computational method is applicable to all datasets collected at a broad range of magnifications using any microscope without need of additional experimental measurements. Moreover, the per-micrograph and/or per-particle level elliptic distortion estimation in our method could resolve potential distortion variations within a cryo-EM dataset, and further improve the 3-D reconstructions relative to constant-value correction by the pre-calibration methods. With successful applications to multiple datasets and cross-validation with the pre-calibration method, we have demonstrated the validity and robustness of our algorithm in estimating the distortion; correction of the elliptic distortion significantly improved the achievable resolutions by ∼1-3 folds and enabled 3-D reconstructions of multiple viral structures at 2.4-2.6Å resolutions. The resolution limits with elliptic distortion and the amounts of resolution improvements with distortion correction were found to strongly correlate with the product of the particle size and the amount of distortion, which can help assess if elliptic distortion is a major resolution limiting factor for single particle cryo-EM projects. PMID:27270241

  7. Insulin dose during glucocorticoid treatment for fetal lung maturation in diabetic pregnancy: test of an algorithm [correction of analgoritm

    DEFF Research Database (Denmark)

    Mathiesen, Elisabeth R; Christensen, Ann-Birgitte L; Hellmuth, Ellinor;

    2002-01-01

    Poor glycemic control is often a serious clinical problem during glucocorticoid treatment for fetal lung maturation in pregnant women with diabetes. An algorithm for improved subcutaneous insulin treatment during glucocorticoid treatment in insulin-dependent diabetic women was developed and tested....

  8. A correct even-odd algorithm for the point-in-polygon (PIP) problem for complex polygons

    OpenAIRE

    Galetzka, Michael; Glauner, Patrick O.

    2012-01-01

    Determining if a point is in a polygon or not is used by a lot of applications in computer graphics, computer games and geoinformatics. Implementing this check is error-prone since there are many special cases to be considered. In this paper we present a simple even-odd algorithm to solve this problem for complex polygons in linear time.

  9. Quadrupole alignment and trajectory correction for future linear colliders. SLC tests of a dispersion-free steering algorithm

    International Nuclear Information System (INIS)

    An experimental study was made on quadrupole alignment with a dispersion-free steering algorithm aiming to demonstrate the performance of advanced beam-based alignment techniques in linear colliders and to anticipate possible reality-related problems. When the dispersion free steering algorithm was tested in the SLC at low current, the dispersion was reduced by factors of 2 - 5 as was shown with two methods; lattice scaling and energy changes. Unexpected limitations in the performance of the algorithm were observed. The causing limiting effects would be improved by cutting the overpopulated non-Gaussian tails of the measurements and monitoring of the SLC optics. Thus, a significantly improved performance of the method in future experiments at the SLC is expected. Dispersion-free and wakefield-free steering allow a fast alignment of the linac in less than roughly 10 minutes. However, both methods are more sensitive to systematic errors than the local beam-based alignment methods. And the local methods are significantly slower. The stability of quadrupole and BPM alignment will decide what method can be used with the highest efficiency. (M.N.)

  10. SMS design and aberration theory

    OpenAIRE

    Corrente, Fabio; Benitez Gimenez, Pablo; Lin WANG; Miñano Dominguez, Juan Carlos; Muñoz, Fernando

    2012-01-01

    The SMS, Simultaneous Multiple Surfaces, design was born to Nonimaging Optics applications and is now being applied also to Imaging Optics. In this paper the wave aberration function of a selected SMS design is studied. It has been found the SMS aberrations can be analyzed with a little set of parameters, sometimes two. The connection of this model with the conventional aberration expansion is also presented. To verify these mathematical model two SMS design systems were raytraced and the dat...

  11. Evaluation of the Analytical Anisotropic Algorithm (AAA) in dose calculation for fields with non-uniform fluences considering heterogeneity correction

    International Nuclear Information System (INIS)

    The purpose of this study is to evaluate the calculation of dose distribution AAA (Varian Medical Systems) for fields with non-uniform fluences considering heterogeneity correction. Five different phantoms were used with different density materials. These phantoms were scanned in the CT BrightSpeed (©GE Healthcare) upon the array of detectors MAPCHECK2 TM (Sun Nuclear Corporation) and irradiated in a linear accelerator 600 CD (Varian Medical Systems) 6MV and rate dose 400MU/min with isocentric setup. The fluences used were exported from IMRT plans, calculated by ECLIPSE™ planning system (Varian Medical Systems), and a 10x10 cm2 field to assess the heterogeneity correction for uniform fluence. The measured dose distribution was compared to the calculated by Gamma analysis with approval criteria of 3% / 3 mm and 10% threshold. The evaluation was performed using the software SNCPatient (Sun Nuclear Corporation) and considering absolute dose normalized at maximum. The phantoms best performers were those with low density materials, with an average of 99.2% approval. Already phantoms with plates of higher density material presented various fluences below 95% of the points approved. The average value reached 94.3%. It was observed a dependency between fluency and approved percentage points, whereas for the same fluency, 100% of the points have been approved in all phantoms. The approval criteria for IMRT plans recommended in most centers is 3% / 3mm with at least 95% of points approved, it can be concluded that, under these conditions, the IMRT plans with heterogeneity correction can be performed , however the quality control must be careful because the difficulty of the system to accurately predict the dose distribution in certain situations. (author)

  12. An improvement to the volcano-scan algorithm for atmospheric correction of CRISM and OMEGA spectral data

    CERN Document Server

    McGuire, Patrick C; Brown, Adrian J; Fraeman, Abigail A; Marzo, Giuseppe A; Morgan, M Frank; Murchie, Scott L; Mustard, John F; Parente, Mario; Pelkey, Shannon M; Roush, Ted L; Seelos, Frank P; Smith, Michael D; Wendt, Lorenz; Wolff, Michael J

    2009-01-01

    The observations of Mars by the CRISM and OMEGA hyperspectral imaging spectrometers require correction for photometric, atmospheric and thermal effects prior to the interpretation of possible mineralogical features in the spectra. Here, we report on a simple, yet non-trivial, adaptation to the commonly-used volcano-scan correction technique for atmospheric CO_2, which allows for the improved detection of minerals with intrinsic absorption bands at wavelengths between 1.9-2.1 $\\mu$m. This volcano-scan technique removes the absorption bands of CO_2 by ensuring that the Lambert albedo is the same at two wavelengths: 1.890 $\\mu$m and 2.011 $\\mu$m, with the first wavelength outside the CO_2 gas bands and the second wavelength deep inside the CO_2 gas bands. Our adaptation to the volcano-scan technique moves the first wavelength from 1.890 $\\mu$m to be instead within the gas bands at 1.980 $\\mu$m, and for CRISM data, our adaptation shifts the second wavelength slightly, to 2.007 $\\mu$m. We also report on our effort...

  13. SU-E-I-05: A Correction Algorithm for Kilovoltage Cone-Beam Computed Tomography Dose Calculations in Cervical Cancer Patients

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, J; Zhang, W; Lu, J [Cancer Hospital of Shantou University Medical College, Shantou, Guangdong (China)

    2015-06-15

    Purpose: To investigate the accuracy and feasibility of dose calculations using kilovoltage cone beam computed tomography in cervical cancer radiotherapy using a correction algorithm. Methods: The Hounsfield units (HU) and electron density (HU-density) curve was obtained for both planning CT (pCT) and kilovoltage cone beam CT (CBCT) using a CIRS-062 calibration phantom. The pCT and kV-CBCT images have different HU values, and if the HU-density curve of CBCT was directly used to calculate dose in CBCT images may have a deviation on dose distribution. It is necessary to normalize the different HU values between pCT and CBCT. A HU correction algorithm was used for CBCT images (cCBCT). Fifteen intensity-modulated radiation therapy (IMRT) plans of cervical cancer were chosen, and the plans were transferred to the pCT and cCBCT data sets without any changes for dose calculations. Phantom and patient studies were carried out. The dose differences and dose distributions were compared between cCBCT plan and pCT plan. Results: The HU number of CBCT was measured by several times, and the maximum change was less than 2%. To compare with pCT, the CBCT and cCBCT has a discrepancy, the dose differences in CBCT and cCBCT images were 2.48%±0.65% (range: 1.3%∼3.8%) and 0.48%±0.21% (range: 0.1%∼0.82%) for phantom study, respectively. For dose calculation in patient images, the dose differences were 2.25%±0.43% (range: 1.4%∼3.4%) and 0.63%±0.35% (range: 0.13%∼0.97%), respectively. And for the dose distributions, the passing rate of cCBCT was higher than the CBCTs. Conclusion: The CBCT image for dose calculation is feasible in cervical cancer radiotherapy, and the correction algorithm offers acceptable accuracy. It will become a useful tool for adaptive radiation therapy.

  14. Cosmological parameter estimation: impact of CMB aberration

    CERN Document Server

    Catena, Riccardo

    2012-01-01

    The peculiar motion of an observer with respect to the CMB rest frame induces an apparent deflection of the observed CMB photons, i.e. aberration, and a shift in their frequency, i.e. Doppler effect. Both effects distort the temperature multipoles a_lm's via a mixing matrix at any l. The common lore when performing a CMB based cosmological parameter estimation is to consider that Doppler affects only the l=1 multipole, and neglect any other corrections. In this paper we reconsider the validity of this assumption, showing that it is actually not robust when sky cuts are included to model CMB foreground contaminations. Assuming a simple fiducial cosmological model with five parameters, we simulated CMB temperature maps of the sky in a WMAP-like and in a Planck-like experiment and added aberration and Doppler effects to the maps. We then analyzed with a MCMC in a Bayesian framework the maps with and without aberration and Doppler effects in order to assess the ability of reconstructing the parameters of the fidu...

  15. A simulation based approach to optimize inventory replenishment with RAND algorithm: An extended study of corrected demand using Holt's method for textile industry

    Science.gov (United States)

    Morshed, Mohammad Sarwar; Kamal, Mostafa Mashnoon; Khan, Somaiya Islam

    2016-07-01

    Inventory has been a major concern in supply chain and numerous researches have been done lately on inventory control which brought forth a number of methods that efficiently manage inventory and related overheads by reducing cost of replenishment. This research is aimed towards providing a better replenishment policy in case of multi-product, single supplier situations for chemical raw materials of textile industries in Bangladesh. It is assumed that industries currently pursue individual replenishment system. The purpose is to find out the optimum ideal cycle time and individual replenishment cycle time of each product for replenishment that will cause lowest annual holding and ordering cost, and also find the optimum ordering quantity. In this paper indirect grouping strategy has been used. It is suggested that indirect grouping Strategy outperforms direct grouping strategy when major cost is high. An algorithm by Kaspi and Rosenblatt (1991) called RAND is exercised for its simplicity and ease of application. RAND provides an ideal cycle time (T) for replenishment and integer multiplier (ki) for individual items. Thus the replenishment cycle time for each product is found as T×ki. Firstly, based on data, a comparison between currently prevailing (individual) process and RAND is provided that uses the actual demands which presents 49% improvement in total cost of replenishment. Secondly, discrepancies in demand is corrected by using Holt's method. However, demands can only be forecasted one or two months into the future because of the demand pattern of the industry under consideration. Evidently, application of RAND with corrected demand display even greater improvement. The results of this study demonstrates that cost of replenishment can be significantly reduced by applying RAND algorithm and exponential smoothing models.

  16. The Algorithm Theoretical Basis Document for the Atmospheric Delay Correction to GLAS Laser Altimeter Ranges. Volume 8

    Science.gov (United States)

    Herring, Thomas A.; Quinn, Katherine J.

    2012-01-01

    NASA s Ice, Cloud, and Land Elevation Satellite (ICESat) mission will be launched late 2001. It s primary instrument is the Geoscience Laser Altimeter System (GLAS) instrument. The main purpose of this instrument is to measure elevation changes of the Greenland and Antarctic icesheets. To accurately measure the ranges it is necessary to correct for the atmospheric delay of the laser pulses. The atmospheric delay depends on the integral of the refractive index along the path that the laser pulse travels through the atmosphere. The refractive index of air at optical wavelengths is a function of density and molecular composition. For ray paths near zenith and closed form equations for the refractivity, the atmospheric delay can be shown to be directly related to surface pressure and total column precipitable water vapor. For ray paths off zenith a mapping function relates the delay to the zenith delay. The closed form equations for refractivity recommended by the International Union of Geodesy and Geophysics (IUGG) are optimized for ground based geodesy techniques and in the next section we will consider whether these equations are suitable for satellite laser altimetry.

  17. 基于KNN模型的层次纠错输出编码算法%Output code algorithm for ierarchical error correcting based on KNNModel

    Institute of Scientific and Technical Information of China (English)

    辛轶; 郭躬德; 陈黎飞; 黄杰

    2009-01-01

    Error Correcting Output Codes (ECOC) is an effective algorithm to handle multi-class problem; however, the ECOC coding is only on the class level and the ECOC matrix is pre-designed. A novel classification algorithm based on hierarchical ECOC was proposed. The algorithm first used KNNModel to build multiple clusters on a given dataset and chose few clusters for each class as representatives to construct a hieratical coding matrix in training phase, and then the matrix was used to train each single classifier. In testing phase, the proposed method makes the most of the merits of KNNModel and ECOC through models combination. Experimental results in the UCI data sets show the effectiveness of the proposed method.%纠错输出编码是一种解决多类分类问题的有效方法,但其编码矩阵只对类进行编码且都采用事先构造出来的统一形式,适应性较差.为此,提出一种新颖的层次纠错输出编码算法.该算法在训练阶段先通过KNN模型算法在数据集上构建多个同类簇,选取各类中最具代表性的簇形成层次编码矩阵,然后再根据编码矩阵进行单分类器训练.在测试阶段,该算法通过模型融合进一步发挥KNN模型和纠错输出编码各自的优点.在UCI公共数据集上的实验结果表明,新方法的性能优于KNN模型算法和纠错输出编码算法.

  18. Hybrid Wireless Mobile Localization Algorithm Based on Error Correction%基于误差修正的混合无线移动定位算法

    Institute of Scientific and Technical Information of China (English)

    李炜

    2013-01-01

    In order to improve localization precision of the wireless mobile,a localization algorithm is proposed based on TDOA-AOA and least squares support vector machine which is used to correct the error.Firstly,leastsquares support vector machine which has nonlinear learning ability is used to modify the measurement error and NLOS error,and then TDOA-AOA is used to estimate the moving endpoint position.Finally,the performance of LSSVM-TDOA-AOA is tested by simulation experiment.The simulation results show that the proposed algorithm has improved the localization precision of the wireless mobile,and the localization error is obviously lower than the compared algorithm,it can meet the practical requirements of wireless mobile communication localization.%为了提高无线移动定位精度,提出一种基于最小二乘支持向量机修改误差的TDOA-AOA定位算法.该方法首先通过非线性学习能力强的最小二乘支持向量机对测量误差和NLOS误差进行修正,然后利用TDOA-AOA算法对移动端点位置进行估计,最后通过仿真实验测试LSSVM-TDOA-AOA的定位性能.仿真结果表明,LSSVM-TDOA-AOA提高了移动端点位置估计精度,定位误差明显低于对比算法,可以较好地满足实际无线移动通信定位要求.

  19. Spelling Correction in Context

    OpenAIRE

    Pinot, Guillaume; Enguehard, Chantal

    2005-01-01

    International audience Spelling checkers, frequently used nowadays, do not allow to correct real-word errors. Thus, the erroneous replacement of dessert by desert is not detected. We propose in this article an algorithm based on the examination of the context of words to correct this kind of spelling errors. This algorithm uses a training on a raw corpus.

  20. Spherical aberration from trajectories in real and hard-edge solenoid fields

    Indian Academy of Sciences (India)

    BISWAS B

    2016-06-01

    For analytical, real and hard-edge solenoidal axial magnetic fields, the low-energy electron trajectories are obtained using the third-order paraxial ray equation. Using the particle trajectories, it is shown that the spherical aberration in the hard-edge model is high and it increases monotonously with hard edginess, although the focal length converges, in agreement with a recentfield and spherical aberration model. The model paved the way for a hard-edge approximation that gives correct focal length and spherical aberration, which is verified here by the trajectory method. In essence, we show that exact hard-edge fields give infinite spherical aberrations.

  1. Study of the wavefront aberrations in children with amblyopia

    Institute of Scientific and Technical Information of China (English)

    ZHAO Peng-fei; ZHOU Yue-hua; WANG Ning-li; ZHANG Jing

    2010-01-01

    Background Amblyopia is a common ophthalmological condition and the wavefront aberrometer is a relatively new diagnostic tool used globally to measure optical characteristics of human eyes as well as to study refractive errors in amblyopic eyes. We studied the wavefront aberration of the amblyopic children's eyes and analyzed the mechanism of the wavefront aberration in the formation of the amblyopia, try to investigate the new evidence of the treatment of the amblyopia, especially in the refractory amblyopia.Methods The WaveScan Wavefront System (VISX, USA) aberrometer was used to investigate four groups of children under dark accommodation and cilliary muscle paralysis. There were 45 cases in the metropic group, 87 in the amblyopic group, 92 in the corrected-amblyopic group and 38 in the refractory amblyopic group. One-way analysis of variance (ANOVA), t-test and multivariate linear regression were used to analyze all the data.Results Third order to 6th order aberrations showed a decreasing trend whereas in the higher order aberrations the main ones were 3rd order coma (Z3-1-Z31), trefoil (Z3-3-Z33) and 4th order aberration (Z40); and 3rd order coma represented the highest percentage of all three main aberrations. Within 3rd order coma, vertical coma (Z3-1) accounted for a greater percentage than horizontal coma (Z31). Significant differences of vertical coma were found among all clinical groups of children: vertical coma in the amblyopic group (0.17±0.15) was significantly higher than in the metropic group (0.11±0.13, P0.05).Conclusions Although lower order aberrations such as defocus (myopia and hyperopia) and astigmatism are major factors determining the quality of the retinal image, higher order aberrations also need to be considered in amblyopic eyes as their effects are significant.

  2. Phase aberration effects in elastography.

    Science.gov (United States)

    Varghese, T; Bilgen, M; Ophir, J

    2001-06-01

    In sonography, phase aberration plays a role in the corruption of sonograms. Phase aberration does not have a significant impact on elastography, if statistically similar phase errors are present in both the pre- and postcompression signals. However, if the phase errors are present in only one of the pre- or postcompression signal pairs, the precision of the strain estimation process will be reduced. In some cases, increased phase errors may occur only in the postcompression signal due to changes in the tissue structure with the applied compression. Phase-aberration effects increase with applied strain and may be viewed as an image quality derating factor, much like frequency-dependent attenuation or undesired lateral tissue motion. In this paper, we present a theoretical and simulation study of the effects of phase aberration on the elastographic strain-estimation process, using the strain filter approach.

  3. Adaptive optics full-field OCT: a resolution almost insensitive to aberrations (Conference Presentation)

    Science.gov (United States)

    Xiao, Peng; Fink, Mathias; Boccara, A. Claude

    2016-03-01

    A Full-Field OCT (FFOCT) setup coupled to a compact transmissive liquid crystal spatial light modulator (LCSLM) is used to induce or correct aberrations and simulate eye examinations. To reduce the system complexity, strict pupil conjugation was abandoned. During our work on quantifying the effect of geometrical aberrations on FFOCT images, we found that the image resolution is almost insensitive to aberrations. Indeed if the object channel PSF is distorted, its interference with the reference channel conserves the main feature of an unperturbed PSF with only a reduction of the signal level. This unique behavior is specific to the use of a spatially incoherent illumination. Based on this, the FFOCT image intensity was used as the metric for our wavefront sensorless correction. Aberration correction was first conducted on an USAF resolution target with the LSCLM as both aberration generator and corrector. A random aberration mask was induced, and the low-order Zernike Modes were corrected sequentially according to the intensity metric function optimization. A Ficus leaf and a fixed mouse brain tissue slice were also imaged to demonstrate the correction of sample self-induced wavefront distortions. After optimization, more structured information appears for the leaf imaging. And the high-signal fiber-like myelin fiber structures were resolved much more clearly after the whole correction process for mouse brain imaging. Our experiment shows the potential of this compact AO-FFOCT system for aberration correction imaging. This preliminary approach that simulates eyes aberrations correction also opens the path to a simple implementation of FFOCT adaptive optics for retinal examinations.

  4. DNA Repair Defects and Chromosomal Aberrations

    Science.gov (United States)

    Hada, Megumi; George, K. A.; Huff, J. L.; Pluth, J. M.; Cucinotta, F. A.

    2009-01-01

    Yields of chromosome aberrations were assessed in cells deficient in DNA doublestrand break (DSB) repair, after exposure to acute or to low-dose-rate (0.018 Gy/hr) gamma rays or acute high LET iron nuclei. We studied several cell lines including fibroblasts deficient in ATM (ataxia telangiectasia mutated; product of the gene that is mutated in ataxia telangiectasia patients) or NBS (nibrin; product of the gene mutated in the Nijmegen breakage syndrome), and gliomablastoma cells that are proficient or lacking in DNA-dependent protein kinase (DNA-PK) activity. Chromosomes were analyzed using the fluorescence in situ hybridization (FISH) chromosome painting method in cells at the first division post irradiation, and chromosome aberrations were identified as either simple exchanges (translocations and dicentrics) or complex exchanges (involving >2 breaks in 2 or more chromosomes). Gamma irradiation induced greater yields of both simple and complex exchanges in the DSB repair-defective cells than in the normal cells. The quadratic dose-response terms for both simple and complex chromosome exchanges were significantly higher for the ATM- and NBS-deficient lines than for normal fibroblasts. However, in the NBS cells the linear dose-response term was significantly higher only for simple exchanges. The large increases in the quadratic dose-response terms in these repair-defective cell lines points the importance of the functions of ATM and NBS in chromatin modifications to facilitate correct DSB repair and minimize the formation of aberrations. The differences found between ATM- and NBS-deficient cells at low doses suggest that important questions should with regard to applying observations of radiation sensitivity at high dose to low-dose exposures. For aberrations induced by iron nuclei, regression models preferred purely linear dose responses for simple exchanges and quadratic dose responses for complex exchanges. Relative biological effectiveness (RBE) factors of all of

  5. Influence of spherical aberrations on fundamental mode beam quality under different laser resonators

    Institute of Scientific and Technical Information of China (English)

    Xiang Zhen; Hu Miao; Ge Jian-Hong; Zhao Zhi-Gang; Wang Sha; Liu Chong; Chen Jun

    2009-01-01

    Spherical aberrations of the thermal lens of the active media are severe when solid state lasers are strongly pumped.The fundamental mode profile deteriorates due to the aberrations. Self-consistent modes of a resonator with aberrations are calculated by using the Fox-Li diffraction iterative algorithm. Calculation results show that the aberration induced fundamental mode beam quality deterioration depends greatly on the resonator design. The tolerance of a flat-flat resonator to the aberration coefficient is about 30λ in the middle of stability, where λ is the wavelength of laser beam. But for a dynamically stable resonator, 2λ of spherical aberration will create diffraction loss of more than 40%, if inappropriate design criteria are used. A birefringence compensated laser resonator with two Nd:YAG rods is experimentally studied. The experimental data are in quite good agreement with simulation results.

  6. Evaluation and Analysis of SEASAT-A Scanning Multichannel Microwave Radiometer (SSMR) Antenna Pattern Correction (APC) Algorithm. Sub-task 4: Interim Mode T Sub B Versus Cross and Nominal Mode T Sub B

    Science.gov (United States)

    Kitzis, J. L.; Kitzis, S. N.

    1979-01-01

    The brightness temperature data produced by the SMMR Antenna Pattern Correction algorithm are evaluated. The evaluation consists of: (1) a direct comparison of the outputs of the interim, cross, and nominal APC modes; (2) a refinement of the previously determined cos beta estimates; and (3) a comparison of the world brightness temperature (T sub B) map with actual SMMR measurements.

  7. Comparison of two heterogeneity correction algorithms in pituitary gland treatments with intensity-modulated radiation therapy; Comparacao de dois algoritmos de correcao de heterogeneidade em tratamentos de tumores de hipofise com radioterapia de intensidade modulada

    Energy Technology Data Exchange (ETDEWEB)

    Albino, Lucas D.; Santos, Gabriela R.; Ribeiro, Victor A.B.; Rodrigues, Laura N., E-mail: lucasdelbem1@gmail.com [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Faculdade de Medicina. Instituto de Radiologia; Weltman, Eduardo; Braga, Henrique F. [Instituto do Cancer do Estado de Sao Paulo, Sao Paulo, SP (Brazil). Servico de Radioterapia

    2013-12-15

    The dose accuracy calculated by a treatment planning system is directly related to the chosen algorithm. Nowadays, several calculation doses algorithms are commercially available and they differ in calculation time and accuracy, especially when individual tissue densities are taken into account. The aim of this study was to compare two different calculation algorithms from iPlan®, BrainLAB, in the treatment of pituitary gland tumor with intensity-modulated radiation therapy (IMRT). These tumors are located in a region with variable electronic density tissues. The deviations from the plan with no heterogeneity correction were evaluated. To initial validation of the data inserted into the planning system, an IMRT plan was simulated in a anthropomorphic phantom and the dose distribution was measured with a radiochromic film. The gamma analysis was performed in the film, comparing it with dose distributions calculated with X-ray Voxel Monte Carlo (XVMC) algorithm and pencil beam convolution (PBC). Next, 33 patients plans, initially calculated by PBC algorithm, were recalculated with XVMC algorithm. The treatment volumes and organs-at-risk dose-volume histograms were compared. No relevant differences were found in dose-volume histograms between XVMC and PBC. However, differences were obtained when comparing each plan with the plan without heterogeneity correction. (author)

  8. Aberration corrected STEM to study an ancient hair dyeing formula

    Science.gov (United States)

    Patriarche, G.; Van Elslande, E.; Castaing, J.; Walter, P.

    2014-05-01

    Lead-based chemistry was initiated in ancient Egypt for cosmetic preparation more than 4000 years ago. Here, we study a hair-dyeing recipe using lead salts described in text since Greco-Roman times. We report direct evidence about the shape and distribution of PbS nanocrystals that form within the hair during blackening.

  9. Tomographic diffractive microscopy and multiview profilometry with flexible aberration correction.

    Science.gov (United States)

    Liu, H; Bailleul, J; Simon, B; Debailleul, M; Colicchio, B; Haeberlé, O

    2014-02-01

    We have developed a tomographic diffractive microscope in reflection, which permits observation of sample surfaces with an improved lateral resolution, compared to a conventional holographic microscope. From the same set of data, high-precision measurements can be performed on the shape of the reflective surface by reconstructing the phase of the diffracted field. Doing so allows for several advantages compared to classical holographic interferometric measurements: improvement in lateral resolution, easier phase unwrapping, reduction of the coherent noise, combined with the high-longitudinal precision provided by interferometric phase measurements. We demonstrate these capabilities by imaging various test samples. PMID:24514193

  10. Chlorophyll-a concentration estimation with three bio-optical algorithms: correction for the low concentration range for the Yiam Reservoir, Korea

    Science.gov (United States)

    Bio-optical algorithms have been applied to monitor water quality in surface water systems. Empirical algorithms, such as Ritchie (2008), Gons (2008), and Gilerson (2010), have been applied to estimate the chlorophyll-a (chl-a) concentrations. However, the performance of each algorithm severely degr...

  11. A DV-HOP algorithm based on RSSI hop count correction and hop distance weighted processing%基于 RSSI值跳数修正和跳距加权处理的DV-HOP算法

    Institute of Scientific and Technical Information of China (English)

    雷高祥; 黄辉; 方旺盛

    2015-01-01

    针对传统DV-Hop定位算法在计算节点间的跳数和平均跳距存在的误差,提出了一种基于RSSI值跳数修正和跳距加权修正的DV-HOP算法. 首先,采取节点RSSI比值修正跳数;然后选择距离未知节点最近的3个锚节点, 并利用修正后的跳数求加权系数对平均跳距进行加权修正. 仿真结果表明:在相同的网络环境下,该算法没有增加其他硬件开销,并且定位误差相对于传统DV-Hop算法有一定减少.%To reduce the errors in calculating the hop count and average hop distance between nodes by the traditional DV-Hop localization algorithm, this paper presents a DV-HOP algorithm based on the ratio between node RSSI and the critical RSSI hop count correction and hop distance weighted revaluation. Firstly, the correction hops are attained by taking the ratio between node RSSI and the critical RSSI corrected hops; then three nearest anchor nodes to the unknown node are chosen, and the average hop distance is corrected by using the weighting coefficient, which is attained through the corrected hop count. The simulation results show that in the same network environment, compared with the traditional DV-Hop algorithm, the proposed algorithm requires only node communication chips with RSSI indicator, without additional hardware expenses, thus effectively reducing the location error.

  12. 基于PDE去鬼影的自适应非均匀性校正算法研究%PDE-based deghosting algorithm for correction of nonuniformity in infrared focal plane array

    Institute of Scientific and Technical Information of China (English)

    张天序; 袁雅婧; 桑红石; 钟胜

    2012-01-01

    针对基于场景的自适应校正算法普遍存在鬼影的问题,分析了神经网络算法( NN-NUC)产生鬼影的原因,并在此基础上提出了用基于偏微分方程(PDE)的非线性滤波方法取代NN-NUC算法中邻域平均的方法来获取期望图像,从而减少边缘像素误差,达到消除鬼影的目的.采用实际采集的红外图像进行实验,结果表明,很好地消除了鬼影.与已有的几种去鬼影的方法相比,具有更快的收敛性.%Generally, most of adaptive nonuniformity correction algorithms have the ghosting artifact problem. In this paper, the cause of ghosting artifacts in Neural Network nonuniformity correction (NN-NUC) algorithm for infrared focal plane array (IRFPA) was studied. Based on the analysis, a novel algorithm for eliminating the ghosting artifact was proposed, which replaces the linear spatial average filter in the NN-NUC algorithm with the partial differential equation (PDE)-based nonlinear filter to estimate the desired image. The comparison experiment using real IRFPA infrared image shows that the proposed algorithm can effectively remove the ghosting artifact. Compared with several deghosting algorithms, the proposed algorithm converges much faster.

  13. Thermal distortion real-time detection and correction of a high-power laser beam-splitter mirror based on double Shack-Hartmann wavefront sensors

    Science.gov (United States)

    Ning, Yu; Sun, Quan; Wang, Hongyan; Wu, Wuming; Du, Shaojun; Xu, Xiaojun

    2015-05-01

    In a high-power laser system, a beam splitter refers to the mirror which locates at the cross point of the path of highpower beam and the weak light section. Because of the thermo-optic effect and elasto-optic effect, a beam splitter deforms under intense laser radiation. This deformation adds extra phase on the incident waves and deliveries inaccurate information to the wavefront sensor. Consequently, the output laser focuses at finite distance and gets divergent when arrives at the target. To settle the above problem, this paper presents a new method for real-time correction of the thermal distortion of beam splitter, based on algorithm of the data fusion of two Shack-Hartmann wavefront sensors (SH-WFS). Different from the traditional AO system, which contains a wavefront sensor, a corrector and a servo controller, two extra Shack-Hartmann wavefront detectors are adopted in our AO system, to detect the transmitted and reflected aberrations of beam splitter mirror. And these aberrations are real-timely delivered to the wavefront sensor. Based on coordinate conversion and data fusion algorithm, it makes the wavefront sensor of AO can "see" the aberrations of splitter mirror by itself. Thus, the servo system controls the corrector to compensate these aberrations correctly. In this paper, the theoretical model of data fusion algorithm is carried out. A closed-loop AO system, which consists of a typical AO system and two extra Shack-Hartmann wavefront detectors, is set up to validate the data fusion algorithm. Experimental results show that, the distortion of a CaF2 beam splitter can be real-time corrected when the AO closedloop control is on. The beam quality factor of output laser decreases from 4 to 1.7 times of diffraction limit.

  14. Analysis of nodal aberration properties in off-axis freeform system design.

    Science.gov (United States)

    Shi, Haodong; Jiang, Huilin; Zhang, Xin; Wang, Chao; Liu, Tao

    2016-08-20

    Freeform surfaces have the advantage of balancing off-axis aberration. In this paper, based on the framework of nodal aberration theory (NAT) applied to the coaxial system, the third-order astigmatism and coma wave aberration expressions of an off-axis system with Zernike polynomial surfaces are derived. The relationship between the off-axis and surface shape acting on the nodal distributions is revealed. The nodal aberration properties of the off-axis freeform system are analyzed and validated by using full-field displays (FFDs). It has been demonstrated that adding Zernike terms, up to nine, to the off-axis system modifies the nodal locations, but the field dependence of the third-order aberration does not change. On this basis, an off-axis two-mirror freeform system with 500 mm effective focal length (EFL) and 300 mm entrance pupil diameter (EPD) working in long-wave infrared is designed. The field constant aberrations induced by surface tilting are corrected by selecting specific Zernike terms. The design results show that the nodes of third-order astigmatism and coma move back into the field of view (FOV). The modulation transfer function (MTF) curves are above 0.4 at 20 line pairs per millimeter (lp/mm) which meets the infrared reconnaissance requirement. This work provides essential insight and guidance for aberration correction in off-axis freeform system design. PMID:27557003

  15. Sensitivity of Satellite-Based Skin Temperature to Different Surface Emissivity and NWP Reanalysis Sources Demonstrated Using a Single-Channel, Viewing-Angle-Corrected Retrieval Algorithm

    Science.gov (United States)

    Scarino, B. R.; Minnis, P.; Yost, C. R.; Chee, T.; Palikonda, R.

    2015-12-01

    Single-channel algorithms for satellite thermal-infrared- (TIR-) derived land and sea surface skin temperature (LST and SST) are advantageous in that they can be easily applied to a variety of satellite sensors. They can also accommodate decade-spanning instrument series, particularly for periods when split-window capabilities are not available. However, the benefit of one unified retrieval methodology for all sensors comes at the cost of critical sensitivity to surface emissivity (ɛs) and atmospheric transmittance estimation. It has been demonstrated that as little as 0.01 variance in ɛs can amount to more than a 0.5-K adjustment in retrieved LST values. Atmospheric transmittance requires calculations that employ vertical profiles of temperature and humidity from numerical weather prediction (NWP) models. Selection of a given NWP model can significantly affect LST and SST agreement relative to their respective validation sources. Thus, it is necessary to understand the accuracies of the retrievals for various NWP models to ensure the best LST/SST retrievals. The sensitivities of the single-channel retrievals to surface emittance and NWP profiles are investigated using NASA Langley historic land and ocean clear-sky skin temperature (Ts) values derived from high-resolution 11-μm TIR brightness temperature measured from geostationary satellites (GEOSat) and Advanced Very High Resolution Radiometers (AVHRR). It is shown that mean GEOSat-derived, anisotropy-corrected LST can vary by up to ±0.8 K depending on whether CERES or MODIS ɛs sources are used. Furthermore, the use of either NOAA Global Forecast System (GFS) or NASA Goddard Modern-Era Retrospective Analysis for Research and Applications (MERRA) for the radiative transfer model initial atmospheric state can account for more than 0.5-K variation in mean Ts. The results are compared to measurements from the Surface Radiation Budget Network (SURFRAD), an Atmospheric Radiation Measurement (ARM) Program ground

  16. Study on the design and Zernike aberrations of a segmented mirror telescope

    Institute of Scientific and Technical Information of China (English)

    Jiang Zhen-Yu; Li Lin; Huang Yi-Fan

    2009-01-01

    The segmented mirror telescope is widely used. The aberrations of segmented mirror systems are different from single mirror systems. This paper uses the Fourier optics theory to analyse the Zernike aberrations of segmented mirror systems. It concludes that the Zernike aberrations of segmented mirror systems obey the linearity theorem. The design of a segmented space telescope and segmented schemes are discussed, and its optical model is constructed. The computer simulation experiment is performed with this optical model to verify the suppositions. The experimental results confirm the correctness of the model.

  17. Aberrant methylation patterns in cancer

    OpenAIRE

    Hudler, Petra; Videtič, Alja

    2016-01-01

    Epigenetic mechanisms, such as DNA methylation, DNA hydroxymethylation, post-translational modifications (PTMs) of histone proteins affecting nucleosome remodelling, and regulation by small and large non-coding RNAs (ncRNAs) work in concert with cis and trans acting elements to drive appropriate gene expression. Advances in detection methods and development of dedicated platforms and methylation arrays resulted in an explo - sion of information on aberrantly methylated sequences linking devia...

  18. Contrast image correction method

    Science.gov (United States)

    Schettini, Raimondo; Gasparini, Francesca; Corchs, Silvia; Marini, Fabrizio; Capra, Alessandro; Castorina, Alfio

    2010-04-01

    A method for contrast enhancement is proposed. The algorithm is based on a local and image-dependent exponential correction. The technique aims to correct images that simultaneously present overexposed and underexposed regions. To prevent halo artifacts, the bilateral filter is used as the mask of the exponential correction. Depending on the characteristics of the image (piloted by histogram analysis), an automated parameter-tuning step is introduced, followed by stretching, clipping, and saturation preserving treatments. Comparisons with other contrast enhancement techniques are presented. The Mean Opinion Score (MOS) experiment on grayscale images gives the greatest preference score for our algorithm.

  19. Evaluation of dose calculation algorithms using the treatment planning system Xi O with tissue heterogeneity correction turned on; Validacao dos algoritmos de calculo de dose do sistema de planejamento Xi O considerando as correcoes para heterogeneidade dos tecidos

    Energy Technology Data Exchange (ETDEWEB)

    Fairbanks, Leandro R.; Barbi, Gustavo L.; Silva, Wiliam T.; Reis, Eduardo G.F.; Borges, Leandro F.; Bertucci, Edenyse C.; Maciel, Marina F.; Amaral, Leonardo L., E-mail: lefairbanks@yahoo.com.b [Universidade de Sao Paulo (HCRP/USP), Ribeirao Preto, SP (Brazil). Hospital das Clinicas. Servico de Radioterapia

    2011-07-01

    Since the cross-section for various radiation interactions is dependent upon tissue material, the presence of heterogeneities affects the final dose delivered. This paper aims to analyze how different treatment planning algorithms (Fast Fourier Transform, Convolution, Superposition, Fast Superposition and Clarkson) work when heterogeneity corrections are used. To that end, a farmer-type ionization chamber was positioned reproducibly (during the time of CT as well as irradiation) inside several phantoms made of aluminum, bone, cork and solid water slabs. The percent difference between the dose measured and calculated by the various algorithms was less than 5%.The convolution method shows better results for high density materials (difference {approx}1 %), whereas the Superposition algorithm is more accurate for low densities (around 1,1%). (author)

  20. Evaluation of dose calculation algorithms using the treatment planning system XiO with tissue heterogeneity correction turned on; Validacao dos algoritmos de calculo de dose do sistema de planejamento XiO considerando as correcoes para heterogeneidade dos tecidos

    Energy Technology Data Exchange (ETDEWEB)

    Fairbanks, L.R.; Barbi, G.L.; Silva, W.T. da; Reis, E.G.F. dos; Borges, L.F.; Bertucci, E.C.; Maciel, M.F.; Amaral, L.L. do, E-mail: lefairbanks@yahoo.com.b [Universidade de Sao Paulo (USP), Ribeirao Preto, SP (Brazil). Hospital das Clinicas. Servico de Radioterapia

    2010-07-01

    Since the cross-section for various radiation interactions is dependent upon tissue material, the presence of heterogeneities affects the final dose delivered. This paper aims to analyze how different treatment planning algorithms (Fast Fourier Transform, Convolution, Superposition, Fast Superposition and Clarkson) work when heterogeneity corrections are used. To that end, a farmer-type ionization chamber was positioned reproducibly (during the time of CT as well as irradiation) inside several phantoms made of aluminum, bone, cork and solid water slabs. The percent difference between the dose measured and calculated by the various algorithms was less than 5%; This is in accordance with the recommendation of several references.The convolution method shows better results for high density materials (difference {approx}1 %), whereas the Superposition algorithm is more accurate for low densities (around 1,1%).

  1. Frequency and distribution studies of asymmetrical versus symmetrical chromosome aberrations

    International Nuclear Information System (INIS)

    Two aspects of the relationship between Asymmetrical (A) and Symmetrical (S) radiation-induced chromosomal aberrations are considered in this paper. (1) Are A and S truly alternative modes of lesion interaction. Relative frequencies for chromatid-type and chromosome-type are examined, and new lymphocyte data using banding is used to look at this, and also for parallelism in chromosome participation of the two forms for various aberration categories. All the tests applied suggest that A and S are alternative interaction modes. (2) The long-term survival characteristics of A and S are discussed, and the differences in expected frequencies of derived S per surviving cell from chromosome-type and chromatid-types are stressed. Since many in vivo tissues have varying mixtures of potential chromatid and chromosome aberration-bearing target cells, ultimate cell survival and derived S frequencies may differ between tissues for the same absorbed dose. An Appendix gives Relative Corrected Lengths (RCL) for chromosomes of the human karyotype which should be used when testing the various exchange aberration categories for random chromosome participation. (orig.)

  2. The Effects of Observation of Learn Units during Reinforcement and Correction Conditions on the Rate of Learning Math Algorithms by Fifth Grade Students

    Science.gov (United States)

    Neu, Jessica Adele

    2013-01-01

    I conducted two studies on the comparative effects of the observation of learn units during (a) reinforcement or (b) correction conditions on the acquisition of math objectives. The dependent variables were the within-session cumulative numbers of correct responses emitted during observational sessions. The independent variables were the…

  3. 机械零件RP中振镜系统校正的几何算法%Geometry Algorithm of Galvanometer System Correction for Rapid Prototyping of Machine Parts

    Institute of Scientific and Technical Information of China (English)

    李广亚; 王玉增; 韩婧茹; 刘双源

    2014-01-01

    Aimed at the linear distortion and nonlinear distortion appeared in laser galvanometer in mechanical parts in rapid pro-totyping,a laser galvanometer graphic correction algorithm was proposed. With using of this algorithm,on one hand,the distortion of linear laser galvanometer appeared in graphic scanning and in that of nonlinear could be eliminated,and on the other hand,compre-hensive error produced in laser galvanometer scanning process could be corrected. Experiments show that the algorithm eliminates the linear and nonlinear distortion generated,and corrects the integrated error produced,which provides satisfactory correction effect for the laser galvanometer in rapid prototyping manufacturing machinery accessories.%针对激光振镜在机械零件快速成型中出现的线性失真和非线性失真,提出了一种激光振镜的图形校正算法。利用该算法一方面可以消除激光振镜在图形扫描中出现的线性失真和非线性失真;另一方面可以校正激光振镜扫描过程中产生的综合误差。实验表明,通过该算法消除了产生的线性失真和非线性失真并且校正了产生的综合误差,为激光振镜在机械零件快速成型制造中提供了满意的校正效果。

  4. Design of a Four-Element, Hollow-Cube Corner Retroreflector for Satellites by use of a Genetic Algorithm.

    Science.gov (United States)

    Minato, A; Sugimoto, N

    1998-01-20

    A four-element retroreflector was designed for satellite laser ranging and Earth-satellite-Earth laser long-path absorption measurement of the atmosphere. The retroreflector consists of four symmetrically located corner retroreflectors. Each retroreflector element has curved mirrors and tuned dihedral angles to correct velocity aberrations. A genetic algorithm was employed to optimize dihedral angles of each element and the directions of the four elements. The optimized four-element retroreflector has high reflectance with a reasonably broad angular coverage. It is also shown that the genetic algorithm is effective for optimizing optics with many parameters.

  5. Atom lens without chromatic aberrations

    CERN Document Server

    Efremov, Maxim A; Schleich, Wolfgang P

    2012-01-01

    We propose a lens for atoms with reduced chromatic aberrations and calculate its focal length and spot size. In our scheme a two-level atom interacts with a near-resonant standing light wave formed by two running waves of slightly different wave vectors, and a far-detuned running wave propagating perpendicular to the standing wave. We show that within the Raman-Nath approximation and for an adiabatically slow atom-light interaction, the phase acquired by the atom is independent of the incident atomic velocity.

  6. Calibration of quasi-static aberrations in exoplanet direct-imaging instruments with a Zernike phase-mask sensor. II. Concept validation with ZELDA on VLT/SPHERE

    Science.gov (United States)

    N'Diaye, M.; Vigan, A.; Dohlen, K.; Sauvage, J.-F.; Caillat, A.; Costille, A.; Girard, J. H. V.; Beuzit, J.-L.; Fusco, T.; Blanchard, P.; Le Merrer, J.; Le Mignant, D.; Madec, F.; Moreaux, G.; Mouillet, D.; Puget, P.; Zins, G.

    2016-08-01

    Warm or massive gas giant planets, brown dwarfs, and debris disks around nearby stars are now routinely observed by dedicated high-contrast imaging instruments that are mounted on large, ground-based observatories. These facilities include extreme adaptive optics (ExAO) and state-of-the-art coronagraphy to achieve unprecedented sensitivities for exoplanet detection and their spectral characterization. However, low spatial frequency differential aberrations between the ExAO sensing path and the science path represent critical limitations for the detection of giant planets with a contrast lower than a few 10-6 at very small separations (reintegration in Chile. Using the internal light source of the instrument, we first performed measurements in the presence of Zernike or Fourier modes introduced with the deformable mirror. Our experimental results are consistent with the results in simulations, confirming the ability of our sensor to measure small aberrations (<50 nm rms) with nanometric accuracy. Following these results, we corrected the long-lived non-common path aberrations in SPHERE based on ZELDA measurements and estimated a contrast gain of 10 in the coronagraphic image at 0.2'', reaching the raw contrast limit set by the coronagraph in the instrument. In addition to this encouraging result, the simplicity of the design and its phase reconstruction algorithm makes ZELDA an excellent candidate for the online measurements of quasi-static aberrations during the observations. The implementation of a ZELDA-based sensing path on the current and future facilities (ELTs, future space missions) could facilitate the observation of cold gaseous or massive rocky planets around nearby stars.

  7. 基于衬底温度的红外焦平面联合非均匀性校正%Combined nonuniformity correction algorithm of infrared focal plane arrays based on substrate temperature

    Institute of Scientific and Technical Information of China (English)

    唐艳秋; 孙强; 赵建; 姚凯男

    2016-01-01

    The advantages and disadvantages in nonuniformity correction (NUC) algorithms based on calibration and scene of infrared focal plane arrays(IRFPA) were analysed separately. The combined NUC algorithm was presented. The thermal imaging system extracted the gain and offset factor from the FLASH which storged beforehand according to the substrate temperature of the IRFPA at the moment of power on. These factor was adopted to remove the nonuniformity of the detector simply. Based on the analysis of the characteristic of residual noise after initial correction, the P-M filter was used to replace the linear spatial average filter in the Neural Network nonuniformity correction algorithm (NN-NUC), which could preserve the image edge. Experimental results show that the proposed algorithm can accelerate the rate of convergence, reduces the correction error largely, and avoids the image degradation caused by the response drift of IRFPA.%分别分析了红外焦平面阵列(IRFPA)基于定标的非均匀性校正法(NUC)和基于场景的NUC算法各自的优势和问题,在此基础上提出了联合非均匀性校正方法。根据上电时刻焦平面衬底的温度值,从FLASH中提取事先存储的对应温度区间的增益和偏置校正参数,初步消除探测器的非均匀性。通过分析初步校正后图像残余非均匀性噪声的特性,提出了用具有保边缘特性的P-M滤波取代传统神经网络算法中的四邻域均值滤波来获得期望图像,从而减小了图像边缘误差。实验结果表明,该算法收敛速度快,校正精度高,有效避免了因红外焦平面响应特性漂移而引起的图像降质。

  8. Effect of methods of myopia correction on visual acuity, contrast sensitivity, and depth of focus

    NARCIS (Netherlands)

    Nio, YK; Jansonius, NM; Wijdh, RHJ; Beekhuis, WH; Worst, JGF; Noorby, S; Kooijman, AC

    2003-01-01

    Purpose. To psychophysically measure spherical and irregular aberrations in patients with various types of myopia correction. Setting: Laboratory of Experimental Ophthalmology, University of Groningen, Groningen, The Netherlands. Methods: Three groups of patients with low myopia correction (spectacl

  9. Patient-specific scatter correction in clinical cone beam computed tomography imaging made possible by the combination of Monte Carlo simulations and a ray tracing algorithm

    DEFF Research Database (Denmark)

    Slot Thing, Rune; Bernchou, Uffe; Mainegra-Hing, Ernesto;

    2013-01-01

    Abstract Purpose. Cone beam computed tomography (CBCT) image quality is limited by scattered photons. Monte Carlo (MC) simulations provide the ability of predicting the patient-specific scatter contamination in clinical CBCT imaging. Lengthy simulations prevent MC-based scatter correction from...

  10. Reduction of dental filling metallic artifacts in CT-based attenuation correction of PET data using weighted virtual sinograms optimized by a genetic algorithm

    NARCIS (Netherlands)

    Abdoli, Mehrsima; Ay, Mohammad Reza; Ahmadian, Alireza; Dierckx, Rudi A. J. O.; Zaidi, Habib

    2010-01-01

    Purpose: The presence of metallic dental fillings is prevalent in head and neck PET/CT imaging and generates bright and dark streaking artifacts in reconstructed CT images. The resulting artifacts would propagate to the corresponding PET images following CT-based attenuation correction (CTAC). This

  11. Nonuniformity correction algorithm for infrared focalplane arrays based on adaptive-filter%基于自适应滤波的红外焦平面阵列非均匀性校正算法

    Institute of Scientific and Technical Information of China (English)

    周慧鑫; 拜丽萍; 秦翰林; 赖睿; 王炳健; 刘群昌

    2009-01-01

    The performance of nonuniformity correction(NUC) would be deteriorated by time shift in the response of detectors in infrared focal plane arrays(IRFPAs). Therefore, a scene-based NUC algorithm is presented. In this algorithm, an adaptive filter bank is applied to estimate NUC parameters for every detector in IRFPAs. And the parameters are renewed by utilizing current imaging information to reduce the influence imposed by response drift on NUC. For an image with a nonuniformity of 26.12%, nonuniformities after 1 h correction are 3.122% for two-point NUC algorithm, 1.893% for Kalman-filter NUC algorithm and around 1.856% for the presented algorithm, which means the presented algorithm can achieve the best NUC effect steadily.%红外探测器响应漂移特性会降低红外焦平面阵列(IRFPA)非均匀性校正的精度.针对该问题提出了一种基于场景的IRFPA非均匀性校正算法.该算法利用所获得的序列成像场景信息,采用一种基于快速自适应滤波器的最优化递归估计方法来获得非均匀性校正参数,并利用当前的成像信息来更新校正参数,以此降低探测器响应漂移特性对非均匀性校正的影响.算法仿真实验显示,对非线性参数为26.12%的同一图像,使用该算法、两点校正算法和卡尔曼滤波校正算法校正1 h后,可分别将非线性参数降至1.856%,3.122%和1.893%,说明该算法可获得稳定而较好的非均匀性校正效果.

  12. Psychometric Characteristics of the Aberrant Behavior Checklist.

    Science.gov (United States)

    Aman, Michael G.; And Others

    1985-01-01

    Information is presented on the psychometric characteristics of the Aberrant Behavior Checklist, a measure of psychotropic drug effects. Internal consistency and test-retest reliability of the checklist appeared very good. Interrater reliability was generally in the moderate range. In general, validity was established for most Aberrant Behavior…

  13. Measuring chromatic aberrations in imaging systems using plasmonic nano-particles

    CERN Document Server

    Gennaro, Sylvain D; Maier, Stefan A; Oulton, Rupert F

    2015-01-01

    Chromatic aberration in optical systems arises from the wavelength dependence of a glass's refractive index. Polychromatic rays incident upon an optical surface are refracted at slightly different angles and in traversing an optical system follow distinct paths creating images displaced according to color. Although arising from dispersion, it manifests as a spatial distortion correctable only with compound lenses with multiple glasses and accumulates in complicated imaging systems. While chromatic aberration is measured with interferometry, simple methods are attractive for their ease of use and low cost. In this letter we retrieve the longitudinal chromatic focal shift of high numerical aperture (NA) microscope objectives from the extinction spectra of metallic nanoparticles within the focal plane. The method is accurate for high NA objectives with apochromatic correction, and enables rapid assessment of the chromatic aberration of any complete microscopy systems, since it is straightforward to implement

  14. Aberration compensation in charged particle projection lithography

    International Nuclear Information System (INIS)

    Projection systems offer the opportunity to increase the throughput for charged particle lithography, because such systems image a large area of a mask directly on to a wafer as a single shot. Shots have to be imaged over a certain range of off-axis distances at the wafer to increase the writing speed, because shot sizes are limited to about 0.25x0.25 mm2 due to aberrations. In a projection system with only lenses, however, the aberrations for off-axis shots are still very large, and some aberration compensation elements need to be introduced. In this paper, three aberration compensation elements (deflectors, stigmators and dynamic focus lenses) are first discussed, a suite of newly developed software, called PROJECTION, based on this principle and our unified aberration theory is then described, and an illustrative example computed with the software is finally given

  15. Distributed weighted node localization algorithm based on Euclidean correction%基于Euclidean修正的分布式加权定位算法

    Institute of Scientific and Technical Information of China (English)

    付锴; 雷勇; 颜嘉俊

    2011-01-01

    The traditional Multi-Dimensional Scaling ( MDS) algorithm adopts multi-hop distance to replace direct  distance, resulting in low accuracy of the local network and large localization error in irregular network. Relative to the existing  algorithms, the paper introduced the Euclidean algorithm to generate accurate multi-hop distance between nodes, and used  weighting mechanism to improve the coefficient of stress. The simulation results show that in low connectivity rectangle network  and C-shape network localization, this method acTheves better performance.%传统的多维定标(MDS)算法由于采用多跳距离代替节点间的直接距离,生成的局部网络准确度低,在不规则网络中定位误差大.相对于现有的算法,引入Euclidean方法来产生多跳节点间的准确距离,并采用一种加权机制来改进协强系数,以抑制累积误差.仿真结果表明该方法在C型网络和低连通度的矩形网络定位中能取得更好的效果.

  16. 汽车前轮转向角测试误差修正算法研究%Algorithm for correcting turning-angle test error of vehicle's front-wheel

    Institute of Scientific and Technical Information of China (English)

    张扬; 张晓光

    2011-01-01

    An algorithm to correct turning-angle test error for vehicle steering-wheel was described in this paper, it used the mechanical structure properties of vehicle steering-axle. By this algorithm, the zero turning-angle starting position of the steering-wheel can be accurately calculated, and then the turning-angle test data can be corrected. Furthermore, the accurate maximum turning angles and related angles of the left and the right steering-wheels can be calculated. It solves the problem that the turning -angle test data for, the steering -wheel has low accuracy and poor repeatability.%提出一种利用汽车转向桥机械结构特性解决汽车转向轮转向角测试误差修正的算法,通过该算法可计算出汽车轮胎准确的零转角起点位置,进而对转角测试数据进行修正,以此计算出准确的左右轮最大转向角及相关角,解决了目前汽车转向轮转向角测试数据准确度低、重复性差的问题.

  17. Removal of ghost images by using tilted element optical systems with polynomial surfaces for aberration compensation

    Science.gov (United States)

    Rogers, Jeremy D.; Tkaczyk, Tomasz S.; Descour, Michael R.; Kärkkäinen, Ari H.; Richards-Kortum, Rebecca

    2006-02-01

    A novel solution to problematic ghost images is implemented by using tilted lens elements with polynomial surfaces. Tilting the lens surfaces sends reflections out of the imaging path. The nonrotationally symmetric polynomial surfaces correct aberrations caused by tilts. The complex lens surfaces are fabricated by using gray-scale lithographic patterning of hybrid solgel glass.

  18. New scene-based nonuniformity correction algorithm based on Gaussian mixture model%基于混合高斯模型的红外图像自适应校正算法

    Institute of Scientific and Technical Information of China (English)

    贾俊涛

    2014-01-01

    针对传统时域高通滤波校正算法存在的鬼影问题,提出一种新的基于混合高斯模型的红外图像自适应校正算法。新算法利用混合高斯模型对场景进行建模,只有在像元输出值满足一定条件的时候,才将其更新到校正系数中,实现有选择性地更新校正系数。通过一组仿真和真实的红外图像序列评价算法的性能,仿真图像采用峰值信噪比指标进行定量评价,新算法比传统时域高通滤波校正算法的峰值信噪比提高了约9 dB。真实图像采用主观的定性评价,传统算法校正结果中存在着明显的鬼影,而新算法校正结果中不存在鬼影。%A new self-adaptive calibration algorithm for infrared images based on Gaussian mixed model (GMM ) was put forward according to traditional temporal high-pass filter (THPF) . GMM is applied in the new algorithm for background modeling ,and only the pixels whose out-put values satisfy certain conditions can be updated to the correction coefficient ,and the back-ground is updated selectively so as to avoid the influence of the foreground target on the update of the background .The performance of the proposed algorithm was evaluated through infrared image sequences with simulated and real fixed-pattern noise ,and the simulated sequences quan-titative evaluation was carried out by using the peak signal noise ratio (PSNR) .Results show that the PSNR of the new algorithm increases by about 9 dB compared with the THPF .The subjective qualitative evaluation was adopted for real images ,the correction results in the tradi-tional method show obvious ghosting artifact w hile the results of the new algorithm are in the absence of ghosting artifact .

  19. 基于仿射修正技术的水下地形ICCP匹配算法%ICCP algorithm for underwater terrain matching navigation based on affine correction

    Institute of Scientific and Technical Information of China (English)

    徐晓苏; 吴剑飞; 徐胜保; 王立辉; 李佩娟

    2014-01-01

    ICCP匹配算法是水下组合导航系统中最为重要的匹配算法。针对传统ICCP匹配算法存在仅对水下航行器惯性导航系统指示航迹作旋转和平移的刚性变换的局限性问题,为提高水下航行器地形辅助导航系统中匹配算法的精度,分析了水下航行器惯性导航系统误差特性,建立了误差模型,提出了基于仿射修正技术的水下地形ICCP匹配算法。首先利用ICCP匹配算法对惯性导航系统指示航迹进行刚性变换,再利用最小二乘法求解仿射参数,进而对 ICCP 匹配航迹进行仿射修正。仿真研究表明,基于仿射修正技术的ICCP匹配算法能较好地解决传统ICCP匹配算法刚性变换的局限性,匹配精度优于传统ICCP算法,匹配误差小于数字地图网格间距的50%,同时仿射修正所耗费时间极少,所增加的时间仅为传统ICCP匹配算法匹配时间的千分之一。%ICCP is the most important matching algorithm used in underwater integrated navigation system. Traditional ICCP algorithm can only do rigid transformation (rotation and translation) for the indicated track of underwater vehicle’s INS. In order to overcome this problem and improve the accuracy of track matching, the error characteristics of INS are analyzed, and the error model of INS is established. Then a new ICCP algorithm based on affine correction is put forward. The track indicated by INS is transformed according to the ICCP algorithm. The affine parameters are solved with the least squares method. The ICCP matching track is modified by affine transformation. The simulations show that the defects of traditional ICCP algorithm can be avoided by affine correction, and the matching result is better than those of traditional ICCP algorithm, in which the matching error is less than 50% of digital map grid spacing. Meanwhile, the additional time consumed in affine correction is just about one thousandth of that in traditional ICCP

  20. Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia

    OpenAIRE

    Yoshida, Mayumi; Kataoka, Naoyuki; Miyauchi, Kenjyo; Ohe, Kenji; Iida, Kei; Yoshida, Suguru; Nojima, Takayuki; Okuno, Yukiko; Onogi, Hiroshi; Usui, Tomomi; Takeuchi, Akihide; Hosoya, Takamitsu; Suzuki, Tsutomu; Hagiwara, Masatoshi

    2015-01-01

    Familial dysautonomia (FD) is caused by missplicing of the IκB kinase complex-associated protein (IKAP) gene, which results in the skipping of exon 20, especially in neurons. FD would be treatable if exon 20 inclusion were increased correctly to reestablish correct splicing. Here, we have established a dual-color splicing reporter that recapitulates FD-type splicing. By using this reporter, we have identified a small chemical compound, named rectifier of aberrant splicing (RECTAS), that recti...

  1. Aberration-Coreected Electron Microscopy at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Zhu,Y.; Wall, J.

    2008-04-01

    The last decade witnessed the rapid development and implementation of aberration correction in electron optics, realizing a more-than-70-year-old dream of aberration-free electron microscopy with a spatial resolution below one angstrom [1-9]. With sophisticated aberration correctors, modern electron microscopes now can reveal local structural information unavailable with neutrons and x-rays, such as the local arrangement of atoms, order/disorder, electronic inhomogeneity, bonding states, spin configuration, quantum confinement, and symmetry breaking [10-17]. Aberration correction through multipole-based correctors, as well as the associated improved stability in accelerating voltage, lens supplies, and goniometers in electron microscopes now enables medium-voltage (200-300kV) microscopes to achieve image resolution at or below 0.1nm. Aberration correction not only improves the instrument's spatial resolution but, equally importantly, allows larger objective lens pole-piece gaps to be employed thus realizing the potential of the instrument as a nanoscale property-measurement tool. That is, while retaining high spatial resolution, we can use various sample stages to observe the materials response under various temperature, electric- and magnetic- fields, and atmospheric environments. Such capabilities afford tremendous opportunities to tackle challenging science and technology issues in physics, chemistry, materials science, and biology. The research goal of the electron microscopy group at the Dept. of Condensed Matter Physics and Materials Science and the Center for Functional Nanomaterials, as well as the Institute for Advanced Electron Microscopy, Brookhaven National Laboratory (BNL), is to elucidate the microscopic origin of the physical- and chemical-behavior of materials, and the role of individual, or groups of atoms, especially in their native functional environments. We plan to accomplish this by developing and implementing various quantitative

  2. Population spherical aberration: associations with ametropia, age, corneal curvature, and image quality

    Directory of Open Access Journals (Sweden)

    Kingston AC

    2013-05-01

    Full Text Available Amanda C Kingston,1,2 Ian G Cox11Bausch + Lomb, Rochester, NY, USA; 2Department of Biomedical Engineering, University of Rochester, Rochester, NY, USAPurpose: The aim of this analysis was to determine the total ocular wavefront aberration values of a large phakic population of physiologically normal, ametropic eyes, gathered under the same clinical protocol using the same diagnostic wavefront sensor.Materials and methods: Studies were conducted at multiple sites in Asia, North America, Europe, and Australia. A Bausch + Lomb Zywave II Wavefront Aberrometer (Rochester, NY, USA was used to measure the lower and higher order aberrations of each eye. Data analysis was conducted using linear regression analysis to determine the relationship between total spherical aberration, ametropia, age, corneal curvature, and image quality.Results: Linear regression analysis showed no correlation (r = 0.0207, P = 0.4874 between degree of ametropia and the amount of spherical aberration. There was also no correlation when the population was stratified into myopic and hyperopic refractive groups (rm = 0.0529, Pm = 0.0804 and rh = 0.1572, Ph = 0.2754. There was a statistically significant and weak positive correlation (r = 0.1962, P < 0.001 between age and the amount of spherical aberration measured in the eye; spherical aberration became more positive with increasing age. Also, there was a statistically significant and moderately positive correlation (r = 0.3611, P < 0.001 with steepness of corneal curvature; spherical aberration became more positive with increasing power of the anterior corneal surface. Assessment of image quality using optical design software (Zemax™, Bellevue, WA, USA showed that there was an overall benefit in correcting the average spherical aberration of this population.Conclusion: Analysis of this dataset provides insights into the inherent spherical aberration of a typical phakic, pre-presbyopic, population and provides the ability to

  3. Chromosome aberration assays in Allium

    Energy Technology Data Exchange (ETDEWEB)

    Grant, W.F.

    1982-01-01

    The common onion (Allium cepa) is an excellent plant for the assay of chromosome aberrations after chemical treatment. Other species of Allium (A. cepa var. proliferum, A. carinatum, A. fistulosum and A. sativum) have also been used but to a much lesser extent. Protocols have been given for using root tips from either bulbs or seeds of Allium cepa to study the cytological end-points, such as chromosome breaks and exchanges, which follow the testing of chemicals in somatic cells. It is considered that both mitotic and meiotic end-points should be used to a greater extent in assaying the cytogenetic effects of a chemical. From a literature survey, 148 chemicals are tabulated that have been assayed in 164 Allium tests for their clastogenic effect. Of the 164 assays which have been carried out, 75 are reported as giving a positive reaction, 49 positive and with a dose response, 1 positive and temperature-related, 9 borderline positive, and 30 negative; 76% of the chemicals gave a definite positive response. It is proposed that the Allium test be included among those tests routinely used for assessing chromosomal damage induced by chemicals.

  4. 冗余余数系统低复杂度快速纠错算法设计%Low-complexity Error Correction Algorithms for Redundant Residue Number Systems

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Redundant Residue Number System (RRNS) is widely used in communication systems for WLAN (Wireless LAN) and CDMA (Code Division Multiple Access) etc. due to its strong ability to enhance robustness of information in parallel processing environments. Error detection and correction of RRNS is an important guarantee for information reliability in communication systems. The overflow detection theorem, the unique theorem, and the searching theorem are proposed and proved in the paper based on properties of residue classes in finite rings. With the theorems, a single-error-correction algorithm using modular operations with reduced complexityO(k/r)is proposed. The uniqueness test algorithm is proposed. Furthermore, for any general types of errors, the searching multiple-error-correction algorithm is proposed. The computational complexity of the searching multiple-error- correction algorithm is reduced from polynomial order to logarithmic order according to the analysis, and the method can reach the extreme correction capability efficiently with only comparison operations instead of complex modular arithmetic.%余数系统由于具有增强传输信息在并行系统中鲁棒性的优势,已被广泛应用在无线局域网(WLAN)以及码分多址通信技术(CDMA)等领域。而余数系统中的纠错检错是保证传输数据可靠性和高效性的关键问题。该文根据有限环上剩余类的性质提出溢出判定定理,不重复判断定理和唯一性区间搜索定理,并在此基础上进一步提出采用模运算代替传统中国剩余定理进行快速恢复的单错误纠错算法,将复杂度降低为O (k/r );提出不重复判定纠错算法;并对于一般错误情形,设计通过比较算子实现的搜索纠错算法。其中搜索纠错算法能直接实现系统最大纠错能力,且避免依靠复杂模运算算子实现,系统吞吐率得以提高;与传统算法相比,计算复杂度由多项式级降低至对数级。

  5. Polarization Aberrations in Astronomical Telescopes: The Point Spread Function

    Science.gov (United States)

    Breckinridge, James B.; Lam, Wai Sze T.; Chipman, Russell A.

    2015-05-01

    and coronagraph applications. (4) Part of the aberration is a polarization-dependent astigmatism, with a magnitude of 22 milliwaves, which enlarges the PSF image. (5) The orthogonally polarized components of unpolarized sources contain different wavefront aberrations, which differ by approximately 32 milliwaves. This implies that a wavefront correction system cannot optimally correct the aberrations for all polarizations simultaneously. (6) The polarization aberrations couple small parts of each polarization component of the light (~10-4) into the orthogonal polarization where these components cause highly distorted secondary, or "ghost" PSF images. (7) The radius of the spatial extent of the 90% encircled energy of these two ghost PSF image is twice as large as the radius of the Airy diffraction pattern. Coronagraphs for terrestrial exoplanet science are expected to image objects 10-10, or 6 orders of magnitude less than the intensity of the instrument-induced "ghost" PSF image, which will interfere with exoplanet measurements. A polarization aberration expansion which approximates the Jones pupil of the example telescope in six polarization terms is presented in the appendix. Individual terms can be associated with particular polarization defects. The dependence of these terms on angles of incidence, numerical aperture, and the Taylor series representation of the Fresnel equations lead to algebraic relations between these parameters and the scaling of the polarization aberrations. These "design rules" applicable to the example telescope are collected in § 5. Currently, exoplanet coronagraph masks are designed and optimized for scalar diffraction in optical systems. Radiation from the "ghost" PSF image leaks around currently designed image plane masks. Here, we show a vector-wave or polarization optimization is recommended. These effects follow from a natural description of the optical system in terms of the Jones matrices associated with each ray path of interest

  6. Flow cytometric detection of aberrant chromosomes

    Energy Technology Data Exchange (ETDEWEB)

    Gray, J.W.; Lucas, J.; Yu, L.C.; Langlois, R.

    1983-05-11

    This report describes the quantification of chromosomal aberrations by flow cytometry. Both homogeneously and heterogeneously occurring chromosome aberrations were studied. Homogeneously occurring aberrations were noted in chromosomes isolated from human colon carcinoma (LoVo) cells, stained with Hoechst 33258 and chromomycin A3 and analyzed using dual beam flow cytometry. The resulting bivariate flow karyotype showed a homogeneously occurring marker chromosome of intermediate size. Heterogeneously occurring aberrations were quantified by slit-scan flow cytometry in chromosomes isolated from control and irradiated Chinese hamster cells and stained with propidium iodide. Heterogeneously occurring dicentric chromosomes were detected by their shapes (two centrometers). The frequencies of such chromosomes estimated by slit-scan flow cytometry correlated well with the frequencies determined by visual microscopy.

  7. Aberration features in directional dark matter detection

    CERN Document Server

    Bozorgnia, Nassim; Gondolo, Paolo

    2012-01-01

    The motion of the Earth around the Sun causes an annual change in the magnitude and direction of the arrival velocity of dark matter particles on Earth, in a way analogous to aberration of stellar light. In directional detectors, aberration of weakly interacting massive particles (WIMPs) modulates the pattern of nuclear recoil directions in a way that depends on the orbital velocity of the Earth and the local galactic distribution of WIMP velocities. Knowing the former, WIMP aberration can give information on the latter, besides being a curious way of confirming the revolution of the Earth and the extraterrestrial provenance of WIMPs. While observing the full aberration pattern requires extremely large exposures, we claim that the annual variation of the mean recoil direction or of the event counts over specific solid angles may be detectable with moderately large exposures. For example, integrated counts over galactic hemispheres separated by planes perpendicular to Earth's orbit would modulate annually, res...

  8. A GPS Independent Geomagnetic Field Mapping and Correction Algorithm%不依赖GPS的磁图测绘与校正新方法

    Institute of Scientific and Technical Information of China (English)

    寇义民; 夏红伟; 刘睿; 王常虹

    2011-01-01

    针对水下磁场测绘中因载体难以经常上浮修正导航误差而导致的测绘结果坐标误差较大的问题,结合磁场测量的特殊性,并采用边导航边校正的思想,提出了一种不依赖GPS的全新磁图测绘方法.首先以惯性导航系统为标准进行第一次测绘并获得具有一定坐标误差的初始磁图,然后对初始磁图进行图形处理与信息提取,在此基础上进行第二次测绘.在第二次测绘中用从初始磁图获得的特征信息结合磁场传感器与惯性器件的输出构建卡尔曼滤波器,从而达到同时修正自身运动状态与初始磁图的目的.理论分析与仿真结果都证实了本方法可以通过两次误差较大的低精度测绘获得精度高得多的测绘结果.%A new algorithm for GPS independenl geomagnetic field mapping is developed in this paper. The idea from the SLAM ( simultaneous localization and mapping) method is implementted here, while several tricks are put forward to make the idea applicable. The algorithm is divided into three steps. Firstly, an inaccurate map is created with magnetic measurement data and position output from inertial navigation systems. Secondly, the map is analyzed and processed to extract shape information. Thirdly, another mapping process is carried out along the same route; meanwhile an extended Kalman filter is constructed by using the shape information of the original map, the status of the inertial navigation system, and the new measurement data. The initial mapping errors and the navigation errors will be estimated and adjusted together after the fiher' s convergence. Theoretical analysis and simulation results both prove that a much more accurate geomagnetic map can be built based on two inaccurate GPS independent surveys.

  9. Explaining algorithms using metaphors

    CERN Document Server

    Forišek, Michal

    2013-01-01

    There is a significant difference between designing a new algorithm, proving its correctness, and teaching it to an audience. When teaching algorithms, the teacher's main goal should be to convey the underlying ideas and to help the students form correct mental models related to the algorithm. This process can often be facilitated by using suitable metaphors. This work provides a set of novel metaphors identified and developed as suitable tools for teaching many of the 'classic textbook' algorithms taught in undergraduate courses worldwide. Each chapter provides exercises and didactic notes fo

  10. Perceived no reference image quality measurement for chromatic aberration

    Science.gov (United States)

    Lamb, Anupama B.; Khambete, Madhuri

    2016-03-01

    Today there is need for no reference (NR) objective perceived image quality measurement techniques as conducting subjective experiments and making reference image available is a very difficult task. Very few NR perceived image quality measurement algorithms are available for color distortions like chromatic aberration (CA), color quantization with dither, and color saturation. We proposed NR image quality assessment (NR-IQA) algorithms for images distorted with CA. CA is mostly observed in images taken with digital cameras, having higher sensor resolution with inexpensive lenses. We compared our metric performance with two state-of-the-art NR blur techniques, one full reference IQA technique and three general-purpose NR-IQA techniques, although they are not tailored for CA. We used a CA dataset in the TID-2013 color image database to evaluate performance. Proposed algorithms give comparable performance with state-of-the-art techniques in terms of performance parameters and outperform them in terms of monotonicity and computational complexity. We have also discovered that the proposed CA algorithm best predicts perceived image quality of images distorted with realistic CA.

  11. An algorithm for temperature correcting substrate moisture measurements: aligning substrate moisture responses with environmental drivers in polytunnel-grown strawberry plants

    Science.gov (United States)

    Goodchild, Martin; Janes, Stuart; Jenkins, Malcolm; Nicholl, Chris; Kühn, Karl

    2015-04-01

    The aim of this work is to assess the use of temperature corrected substrate moisture data to improve the relationship between environmental drivers and the measurement of substrate moisture content in high porosity soil-free growing environments such as coir. Substrate moisture sensor data collected from strawberry plants grown in coir bags installed in a table-top system under a polytunnel illustrates the impact of temperature on capacitance-based moisture measurements. Substrate moisture measurements made in our coir arrangement possess the negative temperature coefficient of the permittivity of water where diurnal changes in moisture content oppose those of substrate temperature. The diurnal substrate temperature variation was seen to range from 7° C to 25° C resulting in a clearly observable temperature effect in substrate moisture content measurements during the 23 day test period. In the laboratory we measured the ML3 soil moisture sensor (ThetaProbe) response to temperature in Air, dry glass beads and water saturated glass beads and used a three-phase alpha (α) mixing model, also known as the Complex Refractive Index Model (CRIM), to derive the permittivity temperature coefficients for glass and water. We derived the α value and estimated the temperature coefficient for water - for sensors operating at 100MHz. Both results are good agreement with published data. By applying the CRIM equation with the temperature coefficients of glass and water the moisture temperature coefficient of saturated glass beads has been reduced by more than an order of magnitude to a moisture temperature coefficient of

  12. The Research and Appliaction of the Multi-classification Algorithm of Error-Correcting Codes Based on Support Vector Machine%基于SVM的纠错编码多分类算法的研究与应用

    Institute of Scientific and Technical Information of China (English)

    祖文超; 苑津莎; 王峰; 刘磊

    2012-01-01

    In order to enhance the accuracy rate of transformer fault diagnosis,multiclass classification algorithm,which is based upon Error-correcting codes connects with SVM,has been proposedThe mathe-matical model of transformer fault diagnosis is set up according to the theory of Support Vector Machine. Firstly,the Error-correcting codes matrix constructs some irrelevant Support Vector Machine,so that the accuracy rate of classified model can be enhanced.Finally,taking the dissolved gases in the transformer oil as the practise and testing sample of Error-correcting codes and SVM to realize transformer fault diagno- sis.And checking the arithmetic by using UCI data.The multiclass classification algorithm has been verified through VS2008 combined with Libsvm has been verified.And the result shows the method has high ac- curacy of classification.%为了提高变压器故障诊断的准确率,提出了一种基于纠错编码和支持向量机相结合的多分类算法,根据SVM理论建立变压器故障诊断数学模型,首先基于纠错编码矩阵构造出若干个互不相关的子支持向量机,以提高分类模型的分类准确率。最后把变压器油中溶解气体(DGA)作为纠错编码支持向量机的训练以及测试样本,实现变压器的故障诊断,同时用UCI数据对该算法进行验证。通过VS2008和Libsvm相结合对其进行验证,结果表明该方法具有很高的分类精度。

  13. Automatic Compensation of Total Phase Aberrations in Digital Holographic Biological Imaging

    International Nuclear Information System (INIS)

    Digital holographic microscopy has been a powerful metrological technique for phase-contrast imaging. However inherent phase aberrations always exist and degrade the quality of the phase-contrast images. A surface fitting method based on an improved mathematic model is proposed, which can be used to remove the phase aberrations without any pre-knowledge of the setup or manual operation. The improved mathematic model includes not only the usual terms but also the cross terms and the high order terms to describe the phase aberrations with high accuracy. Meanwhile, a non-iterative algorithm is used to solve the parametersand thus less computational load is imposed. The proposed method is applied to the live imaging of cells. The experimental results verify its validity. (fundamental areas of phenomenology(including applications))

  14. Computational genes: a tool for molecular diagnosis and therapy of aberrant mutational phenotype

    Directory of Open Access Journals (Sweden)

    Ignatova Zoya

    2007-09-01

    Full Text Available Abstract Background A finite state machine manipulating information-carrying DNA strands can be used to perform autonomous molecular-scale computations at the cellular level. Results We propose a new finite state machine able to detect and correct aberrant molecular phenotype given by mutated genetic transcripts. The aberrant mutations trigger a cascade reaction: specific molecular markers as input are released and induce a spontaneous self-assembly of a wild type protein or peptide, while the mutational disease phenotype is silenced. We experimentally demostrated in in vitro translation system that a viable protein can be autonomously assembled. Conclusion Our work demostrates the basic principles of computational genes and particularly, their potential to detect mutations, and as a response thereafter administer an output that suppresses the aberrant disease phenotype and/or restores the lost physiological function.

  15. Measuring aberrations in the rat brain by coherence-gated wavefront sensing using a Linnik interferometer.

    Science.gov (United States)

    Wang, Jinyu; Léger, Jean-François; Binding, Jonas; Boccara, A Claude; Gigan, Sylvain; Bourdieu, Laurent

    2012-10-01

    Aberrations limit the resolution, signal intensity and achievable imaging depth in microscopy. Coherence-gated wavefront sensing (CGWS) allows the fast measurement of aberrations in scattering samples and therefore the implementation of adaptive corrections. However, CGWS has been demonstrated so far only in weakly scattering samples. We designed a new CGWS scheme based on a Linnik interferometer and a SLED light source, which is able to compensate dispersion automatically and can be implemented on any microscope. In the highly scattering rat brain tissue, where multiply scattered photons falling within the temporal gate of the CGWS can no longer be neglected, we have measured known defocus and spherical aberrations up to a depth of 400 µm.

  16. Simultaneous suppression of scattering and aberration for ultra-high resolution imaging deep within scattering media

    CERN Document Server

    Kang, Sungsam; Kang, Pilsung; Yang, Taeseok D; Ahn, Joonmo; Song, Kyungdeok; Choi, Wonshik

    2016-01-01

    Thick biological tissues give rise to not only the scattering of incoming light waves, but also aberrations of the remaining unscattered waves. Due to the inability of existing optical imaging methodologies to overcome both of these problems simultaneously, imaging depth at the sub- micron spatial resolution has remained extremely shallow. Here we present an experimental approach for identifying and eliminating aberrations even in the presence of strong multiple light scattering. For time-gated complex-field maps of reflected waves taken over various illumination channels, we identify two sets of aberration correction maps, one for the illumination path and one for the reflection path, that can preferentially accumulate the unscattered signal waves over the multiple-scattered waves. By performing closed-loop optimization for forward and phase- conjugation processes, we demonstrated a spatial resolution of 600 nm up to the unprecedented imaging depth of 7 scattering mean free paths.

  17. Measuring aberrations in the rat brain by coherence-gated wavefront sensing using a Linnik interferometer.

    Science.gov (United States)

    Wang, Jinyu; Léger, Jean-François; Binding, Jonas; Boccara, A Claude; Gigan, Sylvain; Bourdieu, Laurent

    2012-10-01

    Aberrations limit the resolution, signal intensity and achievable imaging depth in microscopy. Coherence-gated wavefront sensing (CGWS) allows the fast measurement of aberrations in scattering samples and therefore the implementation of adaptive corrections. However, CGWS has been demonstrated so far only in weakly scattering samples. We designed a new CGWS scheme based on a Linnik interferometer and a SLED light source, which is able to compensate dispersion automatically and can be implemented on any microscope. In the highly scattering rat brain tissue, where multiply scattered photons falling within the temporal gate of the CGWS can no longer be neglected, we have measured known defocus and spherical aberrations up to a depth of 400 µm. PMID:23082292

  18. Effect of a novel motion correction algorithm (SSF) on the image quality of coronary CTA with intermediate heart rates: Segment-based and vessel-based analyses

    Energy Technology Data Exchange (ETDEWEB)

    Li, Qianwen, E-mail: qianwen18@126.com; Li, Pengyu, E-mail: lipyu818@gmail.com; Su, Zhuangzhi, E-mail: suzhuangzhi@xwh.ccmu.edu.cn; Yao, Xinyu, E-mail: 314985151@qq.com; Wang, Yan, E-mail: wy19851121@126.com; Wang, Chen, E-mail: fskwangchen@gmail.com; Du, Xiangying, E-mail: duxying_xw@163.com; Li, Kuncheng, E-mail: kuncheng.li@gmail.com

    2014-11-15

    -segment analysis, IQS was improved in most segments (9/14). Conclusion: The SSF algorithm can provide acceptable diagnostic image quality in coronary CTA for patients with intermediate HR.

  19. Effect of a novel motion correction algorithm (SSF) on the image quality of coronary CTA with intermediate heart rates: Segment-based and vessel-based analyses

    International Nuclear Information System (INIS)

    -segment analysis, IQS was improved in most segments (9/14). Conclusion: The SSF algorithm can provide acceptable diagnostic image quality in coronary CTA for patients with intermediate HR

  20. 过采样滤波器组作为纠错码的阈值新算法%NEW THRESHOLD ALGORITHM WITH OFBS AS ERROR-CORRECTION CODE

    Institute of Scientific and Technical Information of China (English)

    黄晓红; 高荣蔓

    2015-01-01

    考虑量化噪声和信道噪声,搭建基于过采样滤波器组 OFBS(Oversampled Filter Banks)的联合信源信道编码系统,研究系统的传输检错纠错性能。提出新的阈值选取方法,该方法是基于贝叶斯假设检验为理论依据的,能根据实际信号和噪声统计特性做实时分析,得出适当的阈值。通过 Matlab 对系统进行仿真,结果表明信道在不同的转移概率条件,OFBS 作为纠错码的阈值新算法的计算复杂度低,并且有很好的检错纠错性能。通过对一维信号的纠错,信号的峰值信噪比平均提高1到2 db。%Considering the quantisation noise and channel noise,we construct OFBS-based joint source-channel coding (JSCC)system, and study the performance of transmission error detection and correction of the system.We also propose a new threshold selection method, which is based on Bayesian hypothesis testing and takes it for the theoretical basis,it can carry out real-time analysis according to practical signal and noise statistical characteristics to obtain the proper threshold.The system is simulated with Matlab,results show that when channel is under different transition probability conditions,the new threshold algorithm using OFBS as error-correcting codes has low computational complexity,and has good error correction performance as well.Through error correction on one-dimensional signal,the peak signal-noise ratio of the signal improves 1 db to 2 db in average.

  1. 圆形截面管路内PIV流场测量的直接校正方法%Direct Image Correction Algorithm for PIV Measurement of Flowfield within Circular Tube

    Institute of Scientific and Technical Information of China (English)

    刘亦鹏; 胡学羽; 陈佳洛; 王平阳; 杜朝辉

    2013-01-01

    为修正圆形截面管路内PIV(粒子图像测速)流场测量中的图像畸变,建立了一种基于光学原理的直接数值校正方法.该方法不受流体饱和温度限制,可对坐标和速度矢量进行同步校正,壁面附近的光学畸变也能够进行较好还原,同时不需要额外的辅助设备.采用Fortran语言编制了通用的计算机代码,只需改变程序相关输入参数,即可应用于其他条件下的图像校正.使用方形规则化网格对其进行了验证,误差不超过3%.对于双层圆形管壁内低温气液两相流动的PIV流场测量实验,该方法能够给出满意的校正结果.%A direct image correction algorithm based on the optical principle was developed to solve flow-field distortion of particle image velocimetry(PIV) measurement within circular tube. Without the restriction of liquid saturation temperature, this method can be applied for the synchronous correction of coordinate and velocity vector, and can correctly recover the image distortion in the vicinity of tube wall. In addition, this method requires no accessorial device. A computer code was developed based on Fortran language, which can be easily applied to other cases as long as changing the relevant input parameters. The method was validated by using a uniform square grid with the max deviation of 3%. And this method can provide a satisfactory correction result for the PIV experiment of cryogenic gas-liquid two phase flow.

  2. Combining Chromosomal Arm Status and Significantly Aberrant Genomic Locations Reveals New Cancer Subtypes

    Directory of Open Access Journals (Sweden)

    Tal Shay

    2009-01-01

    Full Text Available Many types of tumors exhibit characteristic chromosomal losses or gains, as well as local amplifications and deletions. Within any given tumor type, sample specific amplifications and deletions are also observed. Typically, a region that is aberrant in more tumors, or whose copy number change is stronger, would be considered as a more promising candidate to be biologically relevant to cancer. We sought for an intuitive method to define such aberrations and prioritize them. We define V, the “volume” associated with an aberration, as the product of three factors: (a fraction of patients with the aberration, (b the aberration’s length and (c its amplitude. Our algorithm compares the values of V derived from the real data to a null distribution obtained by permutations, and yields the statistical significance (p-value of the measured value of V. We detected genetic locations that were significantly aberrant, and combine them with chromosomal arm status (gain/loss to create a succinct fingerprint of the tumor genome. This genomic fingerprint is used to visualize the tumors, highlighting events that are co-occurring or mutually exclusive. We apply the method on three different public array CGH datasets of Medulloblastoma and Neuroblastoma, and demonstrate its ability to detect chromosomal regions that were known to be altered in the tested cancer types, as well as to suggest new genomic locations to be tested. We identified a potential new subtype of Medulloblastoma, which is analogous to Neuroblastoma type 1.

  3. Comparison between two different methods to obtain the wavefront aberration function

    Science.gov (United States)

    Cruz Félix, Angel S.; Ibarra, Jorge; López, Estela; Rosales, Marco A.; Tepichín, Eduardo

    2010-08-01

    The analysis and measurement of the wavefront aberration function are very important tools that allow us to evaluate the performance of any specified optical system. This technology has been adopted in visual optics for the analysis of optical aberrations in the human eye, before and after being subjected to laser refractive surgery. We have been working in the characterization and evaluation of the objective performance of human eyes that have been subjected to two different surface ablation techniques known as ASA and PASA1. However, optical aberrations in the human eye are time-dependent2 and, hence, difficult to analyze. In order to obtain a static profile from the post-operatory wavefront aberration function we applied these ablation techniques directly over hard contact lenses. In this work we show the comparison between two different methods to obtain the wavefront aberration function from a reference refractive surface, in order to generalize this method and being able to fully characterize hard contact lenses which have been subjected to different ablation techniques typically used in refractive surgery for vision correction. For the first method we used a Shack-Hartmann wavefront sensor, and in the second method we used a Mach-Zehnder type interferometer. We show the preliminary results of this characterization.

  4. Modelling the formation of polycentric chromosome aberrations

    Energy Technology Data Exchange (ETDEWEB)

    Sachs, R.K.; Tarver, J. (California Univ., Berkeley, CA (United States). Dept. of Mathematics); Yates, B.L.; Morgan, W.F. (California Univ., San Francisco, CA (United States))

    1992-10-01

    Exchange-type chromosome aberrations produced by ionizing radiation or restriction enzymes are believed to result from pairwise interaction of DNA double-strand breaks (dsb). In addition to dicentrics, such aberrations may include higher-order polycentries (tricentries, tetracentrics, etc.). The authors have developed computer programs that calculate the probability of the various polycentrics for a given average number of pairwise interactions. Two models are used. Model I incorporates kinetic competition between restitution, complete exchanges (illegitimate recombination events), and incomplete exchanges. Model II allows unrestituted breaks even if there is no recombination. The models were applied to experimental observations of aberrations produced in G[sub 1] Chinese hamster ovary cells after electroporation with the restriction enzyme PvuII, which produces blunt-end dsb. (author).

  5. Modelling the formation of polycentric chromosome aberrations

    International Nuclear Information System (INIS)

    Exchange-type chromosome aberrations produced by ionizing radiation or restriction enzymes are believed to result from pairwise interaction of DNA double-strand breaks (dsb). In addition to dicentrics, such aberrations may include higher-order polycentries (tricentries, tetracentrics, etc.). The authors have developed computer programs that calculate the probability of the various polycentrics for a given average number of pairwise interactions. Two models are used. Model I incorporates kinetic competition between restitution, complete exchanges (illegitimate recombination events), and incomplete exchanges. Model II allows unrestituted breaks even if there is no recombination. The models were applied to experimental observations of aberrations produced in G1 Chinese hamster ovary cells after electroporation with the restriction enzyme PvuII, which produces blunt-end dsb. (author)

  6. Radial thresholding to mitigate Laser-Guide-Star aberrations on Centre-of-Gravity-based Shack-Hartmann wavefront sensors

    CERN Document Server

    Lardiere, Olivier; Bradley, Colin; Jackson, Kate; Hampton, Peter

    2009-01-01

    Sodium Laser Guide Stars (LGSs) are elongated sources due to the thickness and the finite distance of the sodium layer. The fluctuations of the sodium layer altitude and atom density profile induce errors on centroid measurements of elongated spots, and generate spurious optical aberrations in closed--loop adaptive optics (AO) systems. According to an analytical model and experimental results obtained with the University of Victoria LGS bench demonstrator, one of the main origins of these aberrations, referred to as LGS aberrations, is not the Centre-of-Gravity (CoG) algorithm itself, but the thresholding applied on the pixels of the image prior to computing the spot centroids. A new thresholding method, termed ``radial thresholding'', is presented here, cancelling out most of the LGS aberrations without altering the centroid measurement accuracy.

  7. Adaptive Alternating Minimization Algorithms

    CERN Document Server

    Niesen, Urs; Wornell, Gregory

    2007-01-01

    The classical alternating minimization (or projection) algorithm has been successful in the context of solving optimization problems over two variables or equivalently of finding a point in the intersection of two sets. The iterative nature and simplicity of the algorithm has led to its application to many areas such as signal processing, information theory, control, and finance. A general set of sufficient conditions for the convergence and correctness of the algorithm is quite well-known when the underlying problem parameters are fixed. In many practical situations, however, the underlying problem parameters are changing over time, and the use of an adaptive algorithm is more appropriate. In this paper, we study such an adaptive version of the alternating minimization algorithm. As a main result of this paper, we provide a general set of sufficient conditions for the convergence and correctness of the adaptive algorithm. Perhaps surprisingly, these conditions seem to be the minimal ones one would expect in ...

  8. Higher order aberrations in amblyopic children and their role in refractory amblyopia

    Directory of Open Access Journals (Sweden)

    Arnaldo Dias-Santos

    2014-12-01

    Full Text Available Objective: Some studies have hypothesized that an unfavourable higher order aberrometric profile could act as an amblyogenic mechanism and may be responsible for some amblyopic cases that are refractory to conventional treatment or cases of “idiopathic” amblyopia. This study compared the aberrometric profile in amblyopic children to that of children with normal visual development and compared the aberrometric profile in corrected amblyopic eyes and refractory amblyopic eyes with that of healthy eyes. Methods: Cross-sectional study with three groups of children – the CA group (22 eyes of 11 children with unilateral corrected amblyopia, the RA group (24 eyes of 13 children with unilateral refractory amblyopia and the C group (28 eyes of 14 children with normal visual development. Higher order aberrations were evaluated using an OPD-Scan III (NIDEK. Comparisons of the aberrometric profile were made between these groups as well as between the amblyopic and healthy eyes within the CA and RA groups. Results: Higher order aberrations with greater impact in visual quality were not significantly higher in the CA and RA groups when compared with the C group. Moreover, there were no statistically significant differences in the higher order aberrometric profile between the amblyopic and healthy eyes within the CA and RA groups. Conclusions: Contrary to lower order aberrations (e.g., myopia, hyperopia, primary astigmatism, higher order aberrations do not seem to be involved in the etiopathogenesis of amblyopia. Therefore, these are likely not the cause of most cases of refractory amblyopia.

  9. Relativistic stellar aberration for the Space Interferometry Mission

    CERN Document Server

    Turyshev, S G

    2002-01-01

    This paper analyses the relativistic stellar aberration requirements for the Space Interferometry Mission (SIM). We address the issue of general relativistic deflection of light by the massive self-gravitating bodies. Specifically, we present estimates for corresponding deflection angles due to the monopole components of the gravitational fields of a large number of celestial bodies in the solar system. We study the possibility of deriving an additional navigational constraints from the need to correct for the gravitational bending of light that is traversing the solar system. It turns out that positions of the outer planets presently may not have a sufficient accuracy for the precision astrometry. However, SIM may significantly improve those simply as a by-product of its astrometric program. We also consider influence of the higher gravitational multipoles, notably the quadrupole and the octupole ones, on the gravitational bending of light. Thus, one will have to model and account for their influence while o...

  10. Propagation of Aberrations through Phase Induced Amplitude Apodization coronagraph

    CERN Document Server

    Pueyo, Laurent; Shaklan, Stuart; 10.1364/JOSAA.28.000189

    2011-01-01

    The specification of polishing requirements for the optics in coronagraphs dedicated to exo-planet detection requires careful and accurate optical modelling. Numerical representations of the propagation of aberrations through the system as well as simulations of the broadband wavefront compensation system using multiple DMs are critical when one devises an error budget for such a class of instruments. In this communication we introduce an analytical tool that serves this purpose for Phase Induced Amplitude Apodisation (PIAA) coronagraphs. We first start by deriving the analytical form of the propagation of a harmonic ripple through a PIAA unit. Using this result we derive the chromaticity of the field at any plane in the optical train of a telescope equipped with such a coronagraph. Finally we study the chromatic response of a sequential DM wavefront actuator correcting such a corrugated field and thus quantify the requirements on the manufacturing of PIAA mirrors

  11. 基于区域特征的线阵CCD图像自适应校正%Regional characteristics based Adaptive correction algorithm for linear array CCD images

    Institute of Scientific and Technical Information of China (English)

    尹楠; 顾济华; 邹丽新; 周强; 马心儒

    2013-01-01

    An adaptive correction algorithm is proposed in this paper to correct the distorted linear CCD images when the athletes reach the finish line in a track competition. Firstly, the head inclination and aspect ratio of the athletes are got by using morphological processing for obtaining the transformation factor corresponding to the angle. Then the athlete head is taken as a center, and the appropriate length in the horizontal direction is selected to get the edge abscissa in the horizontal direction to the athlete, and clip the image. The two-dimensional transform matrixes are adopted to make the interpolation projective transfor-mation of the image. The simulation result shows that this algorithm is easy to implement and can restore the distorted images. The satisfying result can be obtained through simulation analysis on the stretch of the normal images.%针对田径比赛中运动员到达终点时线阵CCD采集到的失真图像进行处理,通过对扫描同步的分析,得到了失真图像产生原因,提出了一种自适应的校正算法.首先经形态学处理得到运动员头部的倾角及长宽比,进而得到对应角度的变换因子;然后以头部为中心,在水平方向左右取合适长度,得到运动员水平方向上的边缘横坐标并剪裁图像;最后使用二维变换矩阵对该图像进行插值投影变换.仿真实验表明,该算法简单易行,能较好地还原失真图像.并且通过对正常图像拉伸的仿真分析,得到较为满意的结果.

  12. Prenatal hydronephrosis caused by aberrant renal vessels

    DEFF Research Database (Denmark)

    Lenz, K; Thorup, Jørgen Mogens; Rabol, A;

    1996-01-01

    With routine use of obstetric ultrasonography, fetal low-grade hydronephrosis is commonly detected, but may resolve spontaneously after birth. Two cases are presented to illustrate that in some cases such findings can express intermittent hydronephrosis caused by aberrant renal vessels. Renal...

  13. Anti-forensics of chromatic aberration

    Science.gov (United States)

    Mayer, Owen; Stamm, Matthew C.

    2015-03-01

    Over the past decade, a number of information forensic techniques have been developed to identify digital image manipulation and falsification. Recent research has shown, however, that an intelligent forger can use anti-forensic countermeasures to disguise their forgeries. In this paper, an anti-forensic technique is proposed to falsify the lateral chromatic aberration present in a digital image. Lateral chromatic aberration corresponds to the relative contraction or expansion between an image's color channels that occurs due to a lens's inability to focus all wavelengths of light on the same point. Previous work has used localized inconsistencies in an image's chromatic aberration to expose cut-and-paste image forgeries. The anti-forensic technique presented in this paper operates by estimating the expected lateral chromatic aberration at an image location, then removing deviations from this estimate caused by tampering or falsification. Experimental results are presented that demonstrate that our anti-forensic technique can be used to effectively disguise evidence of an image forgery.

  14. Adaptive and aberrant reward prediction signals in the human brain.

    NARCIS (Netherlands)

    Roiser, J.P.; Stephan, K.E.; Ouden, H.E.M. den; Friston, K.J.; Joyce, E.M.

    2010-01-01

    Theories of the positive symptoms of schizophrenia hypothesize a role for aberrant reinforcement signaling driven by dysregulated dopamine transmission. Recently, we provided evidence of aberrant reward learning in symptomatic, but not asymptomatic patients with schizophrenia, using a novel paradigm

  15. Inclusion of aberrations of a tilted plane-parallel plate in diffraction calculations of the propagation of radiation

    NARCIS (Netherlands)

    Epatko, [No Value; Malyutin, AA; Serov, RV; Solov'ev, DA

    1998-01-01

    An expression is obtained for the aberration operator of a plane-parallel plate and it is shown that its use in the far-field zone makes it possible to take full account of electromagnetic field perturbations. Examples are given of calculations in accordance with the proposed algorithm when the radi

  16. Chromatic aberration and the roles of double-opponent and color-luminance neurons in color vision

    NARCIS (Netherlands)

    Vladusich, Tony

    2007-01-01

    How does the visual cortex encode color? I summarize a theory in which cortical double-opponent color neurons perform a role in color constancy and a complementary set of color-luminance neurons function to selectively correct for color fringes induced by chromatic aberration in the eye. The theory

  17. Differentiated Effects of Sensory Activities as Abolishing Operations via Non-Contingent Reinforcement on Academic and Aberrant Behavior

    Science.gov (United States)

    Mancil, G. Richmond; Haydon, Todd; Boman, Marty

    2016-01-01

    The purpose of the study was to evaluate the effectiveness of sensory activities used as antecedent interventions on the percentage correct on academic tasks and rate of aberrant behavior in three elementary aged children with Autism Spectrum Disorders (ASD). Study activities were conducted in an after school program for children with ASD where…

  18. LSST Telescope Alignment Plan Based on Nodal Aberration Theory

    Science.gov (United States)

    Sebag, J.; Gressler, W.; Schmid, T.; Rolland, J. P.; Thompson, K. P.

    2012-04-01

    The optical alignment of the Large Synoptic Survey Telescope (LSST) is potentially challenging, due to its fast three-mirror optical design and its large 3.5° field of view (FOV). It is highly advantageous to align the three-mirror optical system prior to the integration of the complex science camera on the telescope, which corrects the FOV via three refractive elements and includes the operational wavefront sensors. A telescope alignment method based on nodal aberration theory (NAT) is presented here to address this challenge. Without the science camera installed on the telescope, the on-axis imaging performance of the telescope is diffraction-limited, but the field of view is not corrected. The nodal properties of the three-mirror telescope design have been analyzed and an alignment approach has been developed using the intrinsically linear nodal behavior, which is linked via sensitivities to the misalignment parameters. Since mirror figure errors will exist in any real application, a methodology to introduce primary-mirror figure errors into the analysis has been developed and is also presented.

  19. Assessing the construct validity of aberrant salience

    Directory of Open Access Journals (Sweden)

    Kristin Schmidt

    2009-12-01

    Full Text Available We sought to validate the psychometric properties of a recently developed paradigm that aims to measure salience attribution processes proposed to contribute to positive psychotic symptoms, the Salience Attribution Test (SAT. The “aberrant salience” measure from the SAT showed good face validity in previous results, with elevated scores both in high-schizotypy individuals, and in patients with schizophrenia suffering from delusions. Exploring the construct validity of salience attribution variables derived from the SAT is important, since other factors, including latent inhibition/learned irrelevance, attention, probabilistic reward learning, sensitivity to probability, general cognitive ability and working memory could influence these measures. Fifty healthy participants completed schizotypy scales, the SAT, a learned irrelevance task, and a number of other cognitive tasks tapping into potentially confounding processes. Behavioural measures of interest from each task were entered into a principal components analysis, which yielded a five-factor structure accounting for ~75% percent of the variance in behaviour. Implicit aberrant salience was found to load onto its own factor, which was associated with elevated “Introvertive Anhedonia” schizotypy, replicating our previous finding. Learned irrelevance loaded onto a separate factor, which also included implicit adaptive salience, but was not associated with schizotypy. Explicit adaptive and aberrant salience, along with a measure of probabilistic learning, loaded onto a further factor, though this also did not correlate with schizotypy. These results suggest that the measures of learned irrelevance and implicit adaptive salience might be based on similar underlying processes, which are dissociable both from implicit aberrant salience and explicit measures of salience.

  20. Phase-Locked Fibre Array for Coherent Combination and Atmosphere Aberration Compensation

    Institute of Scientific and Technical Information of China (English)

    HOU Jing; XIAO Rui

    2006-01-01

    We report a fibre amplifier array that not only achieves coherent beam combination by compensation of phase noises of fibre amplifier, but also accomplishes correction of atmosphere aberration. It is of master-oscillatormultiple-amplifier (MOPA) configuration, which can be phase-locked by the multidither principle or heterodyne detection principle. First laboratory experiments of atmosphere aberration compensation of a three-element fibre amplifier array are reported. The atmosphere aberration is created by a phase screen in the experiment. The phase changes of the beam, which are introduced by the fibre amplifier and the phase screen, are both detected by the heterodyne detection method. Phase modulators are controlled to compensate for the phase in the three paths. No matter whether there is a phase screen producing atmosphere aberration or not, the dim dynamic interference fringes in the far field turn to a clear and stable pattern, and the peak intensity is maximized. It is indicated that the fibre amplifier array is phase-locked, and coherent combination of the three beams is achieved.It can be used not only to obtain high power fibre laser array but also in laser space communication.

  1. Chromosome painting in biological dosimetry: Semi-automatic system to score stable chromosome aberrations

    International Nuclear Information System (INIS)

    From the beginning of the description of the procedure of chromosome painting by fluorescence in situ hybridization (FISH), it was thought its possible application to score induced chromosomal aberrations in radiation exposition. With chromosome painting it is possible to detect changes between chromosomes that has been validated in radiation exposition. Translocation scoring by FISH, contrarily to the unstable dicentrics, mainly detect stable chromosome aberrations that do not disappear, it allows the capability of quantify delayed acute expositions or chronic cumulative expositions. The large number of cells that have to be analyzed for high accuracy, specially when dealing with low radiation doses, makes it almost imperative to use an automatic analysis system. After validate translocation scoring by FISH in our, we have evaluated the ability and sensitivity to detect chromosomal aberrations by chromosome using different paint probes used, showing that any combination of paint probes can be used to score induced chromosomal aberrations. Our group has developed a FISH analysis that is currently being adapted for translocation scoring analysis. It includes systematic error correction and internal control probes. The performance tests carried out show that 9,000 cells can be analyzed in 10 hr. using a Sparc 4/370. Although with a faster computer, a higher throughput is expected, for large population screening or very low radiation doses, this performance still has to be improved. (author)

  2. Corrective Jaw Surgery

    Science.gov (United States)

    ... out more. Corrective Jaw Surgery Corrective Jaw Surgery Orthognathic surgery is performed to correct the misalignment of ... out more. Corrective Jaw Surgery Corrective Jaw Surgery Orthognathic surgery is performed to correct the misalignment of ...

  3. On the implications of the Galactic aberration in proper motions for celestial reference frame

    CERN Document Server

    Malkin, Zinovy

    2014-01-01

    During the last years, much attention has been paid to the astrometric implications of the galactic aberration in proper motions (GA). This effect causes systematic errors in astrometric measurements at a microarcsecond level. Some authors consider it so serious that it requires redefinition of the celestial reference system (CRF). We argue that such attention to the GA is too much exaggerated. It is just a small astrometric correction that must be taken into account during highly accurate astrometric and geodetic data processing. The accuracy of this correction depends on accuracy of the Galactic rotation parameters and, for most application, on the accuracy of the rotation matrix between Galactic and equatorial systems. Our analysis has shown that our today knowledge of these two factors is sufficient to compute the GA correction with accuracy of better than 10%. The remaining effect at a level of few tenths microarcsecond/yr is negligible nowadays. Another consequence of introducing the GA correction is ne...

  4. Radiotherapeutical chromosomal aberrations in laryngeal cancer patients

    Directory of Open Access Journals (Sweden)

    Stošić-Divjak Svetlana L.

    2009-01-01

    Full Text Available Introduction. The authors present the results of cytogenetic analysis of 21 patients with laryngeal carcinomas diagnosed and treated in the period 1995-2000 at the Institute of Otorhinolaryngology and Maxillofacial Surgery, Clinical Center of Serbia and Clinical Center of Novi Sad. Material and methods. The patients were specially monitored and the material was analyzed at the Institute of Human Genetics of the School of Medicine in Belgrade as well as in the Laboratory for Radiological Protection of the Institute of Occupational and Radiological Health 'Dr Dragomir Karajovic' in Belgrade. Results. The incidence of chromosomal aberrations and incidence of exchange of material between sister chromatids were observed in the preparation of the metaphasic lymphocyte chromosomes of the peripheral blood obtained in the culture. Structural aberrations were found on the chromosomes in the form of breakups, rings, translocations and dicentrics as early as after a single exposure of patients to tumor radiation dose of 2 Gy in the field sized 5x7. Out of the total number of 35 cultivated blood samples obtained from 13 patients, 21 were successfully cultivated and they were proved to contain chromosomal aberrations. Some of the peripheral blood samples failed to show cell growth in vitro due to the lethal cell damages in vivo. Discussion.. We have consluded that the number of structural aberrations cannot be used as a biological measure of the absorbed ionizing radiation dose. The presence of aberrations per se is indicative of the mutagenic effect of the ionizing radiation, which was also confirmed in our series on the original model by cultivation of the peripheral blood lymphocytes in the culture of the cells of the volunteer donors upon in vitro radiation. Using the method of bromdeoxyuridylreductase, the increased incidence of SCE as a mutagenic effect was registered. Conclusion. It has been concluded that the increase of absorbed radiation dose in

  5. Shell corrections in stopping powers

    Science.gov (United States)

    Bichsel, H.

    2002-05-01

    One of the theories of the electronic stopping power S for fast light ions was derived by Bethe. The algorithm currently used for the calculation of S includes terms known as the mean excitation energy I, the shell correction, the Barkas correction, and the Bloch correction. These terms are described here. For the calculation of the shell corrections an atomic model is used, which is more realistic than the hydrogenic approximation used so far. A comparison is made with similar calculations in which the local plasma approximation is utilized. Close agreement with the experimental data for protons with energies from 0.3 to 10 MeV traversing Al and Si is found without the need for adjustable parameters for the shell corrections.

  6. Combined Approach for Nonuniformity Correction in Infrared Focal Plane Array

    Institute of Scientific and Technical Information of China (English)

    XUE Hui

    2009-01-01

    A new algorithm of nonuniformity correction for infrared focal plane array(IRFPA) is reported,which is a combined algorithm based on both the two-point correction and artificial neural networks correction.The combined algorithm is calibrated by two-point correction,and the calibrated correction coefficients are automatically modified by BP algorithm.So it is not only calibrated,but also real-time processed.In adaptive nonuniformity correction algorithm,the phenomena ghost artifact and target fade-out are avoided by edge extraction.In order to get intensified image,the modified median filters are adopted.The simulated data indicates the proposed scheme is an effective algorithm.

  7. Optimization algorithms and applications

    CERN Document Server

    Arora, Rajesh Kumar

    2015-01-01

    Choose the Correct Solution Method for Your Optimization ProblemOptimization: Algorithms and Applications presents a variety of solution techniques for optimization problems, emphasizing concepts rather than rigorous mathematical details and proofs. The book covers both gradient and stochastic methods as solution techniques for unconstrained and constrained optimization problems. It discusses the conjugate gradient method, Broyden-Fletcher-Goldfarb-Shanno algorithm, Powell method, penalty function, augmented Lagrange multiplier method, sequential quadratic programming, method of feasible direc

  8. Deciphering causal and statistical relations of molecular aberrations and gene expressions in NCI-60 cell lines

    Directory of Open Access Journals (Sweden)

    Li Shyh-Dar

    2011-11-01

    Full Text Available Abstract Background Cancer cells harbor a large number of molecular alterations such as mutations, amplifications and deletions on DNA sequences and epigenetic changes on DNA methylations. These aberrations may dysregulate gene expressions, which in turn drive the malignancy of tumors. Deciphering the causal and statistical relations of molecular aberrations and gene expressions is critical for understanding the molecular mechanisms of clinical phenotypes. Results In this work, we proposed a computational method to reconstruct association modules containing driver aberrations, passenger mRNA or microRNA expressions, and putative regulators that mediate the effects from drivers to passengers. By applying the module-finding algorithm to the integrated datasets of NCI-60 cancer cell lines, we found that gene expressions were driven by diverse molecular aberrations including chromosomal segments' copy number variations, gene mutations and DNA methylations, microRNA expressions, and the expressions of transcription factors. In-silico validation indicated that passenger genes were enriched with the regulator binding motifs, functional categories or pathways where the drivers were involved, and co-citations with the driver/regulator genes. Moreover, 6 of 11 predicted MYB targets were down-regulated in an MYB-siRNA treated leukemia cell line. In addition, microRNA expressions were driven by distinct mechanisms from mRNA expressions. Conclusions The results provide rich mechanistic information regarding molecular aberrations and gene expressions in cancer genomes. This kind of integrative analysis will become an important tool for the diagnosis and treatment of cancer in the era of personalized medicine.

  9. Atmospheric correction of APEX hyperspectral data

    Directory of Open Access Journals (Sweden)

    Sterckx Sindy

    2016-03-01

    Full Text Available Atmospheric correction plays a crucial role among the processing steps applied to remotely sensed hyperspectral data. Atmospheric correction comprises a group of procedures needed to remove atmospheric effects from observed spectra, i.e. the transformation from at-sensor radiances to at-surface radiances or reflectances. In this paper we present the different steps in the atmospheric correction process for APEX hyperspectral data as applied by the Central Data Processing Center (CDPC at the Flemish Institute for Technological Research (VITO, Mol, Belgium. The MODerate resolution atmospheric TRANsmission program (MODTRAN is used to determine the source of radiation and for applying the actual atmospheric correction. As part of the overall correction process, supporting algorithms are provided in order to derive MODTRAN configuration parameters and to account for specific effects, e.g. correction for adjacency effects, haze and shadow correction, and topographic BRDF correction. The methods and theory underlying these corrections and an example of an application are presented.

  10. Aberrant splicing and drug resistance in AML.

    Science.gov (United States)

    de Necochea-Campion, Rosalia; Shouse, Geoffrey P; Zhou, Qi; Mirshahidi, Saied; Chen, Chien-Shing

    2016-01-01

    The advent of next-generation sequencing technologies has unveiled a new window into the heterogeneity of acute myeloid leukemia (AML). In particular, recurrent mutations in spliceosome machinery and genome-wide aberrant splicing events have been recognized as a prominent component of this disease. This review will focus on how these factors influence drug resistance through altered splicing of tumor suppressor and oncogenes and dysregulation of the apoptotic signaling network. A better understanding of these factors in disease progression is necessary to design appropriate therapeutic strategies recognizing specific alternatively spliced or mutated oncogenic targets. PMID:27613060

  11. Aberration-free volumetric high-speed imaging of in vivo retina

    CERN Document Server

    Hillmann, Dierck; Hain, Carola; Sudkamp, Helge; Franke, Gesa; Pfäffle, Clara; Winter, Christian; Hüttmann, Gereon

    2016-01-01

    Research and medicine rely on non-invasive optical techniques to image living tissue with high resolution in space and time. But so far a single data acquisition could not provide entirely diffraction-limited tomographic volumes of rapidly moving or changing targets, which additionally becomes increasingly difficult in the presence of aberrations, e.g., when imaging retina in vivo. We show, that a simple interferometric setup based on parallelized optical coherence tomography acquires volumetric data with 10 billion voxels per second, exceeding previous imaging speeds by an order of magnitude. This allows us to computationally obtain and correct defocus and aberrations resulting in entirely diffraction-limited volumes. As demonstration, we imaged living human retina with clearly visible nerve fiber layer, small capillary networks, and photoreceptor cells, but the technique is also applicable to obtain phase-sensitive volumes of other scattering structures at unprecedented acquisition speeds.

  12. Aberration-free two-thin-lens systems based on negative-index materials

    Institute of Scientific and Technical Information of China (English)

    Lin Zhi-Li; Ding Jie-Chen; Zhang Pu

    2008-01-01

    Since the complete correction of all five monochromatic Seidel aberrations for a singlet lens with random shape or a two-thin-lens system is unprocurable merely by using the conventional positive-index materials both in theory and practice, this paper proposes that when one or both of the two lenses is/are made from negative-index materials, an imaging system composed of a pair of spherical thin lenses is possible to form a real image, in air, free from all five monochromatic Seidel aberrations. The calculated numerical solutions to the structural parameters of such lens systems possessing superior performance are provided and examples of them are illustrated for the given combinations of the two lenses' refractive indices, including an ultimately-remote imaging system.

  13. Totally Corrective Boosting for Regularized Risk Minimization

    CERN Document Server

    Shen, Chunhua; Barnes, Nick

    2010-01-01

    Consideration of the primal and dual problems together leads to important new insights into the characteristics of boosting algorithms. In this work, we propose a general framework that can be used to design new boosting algorithms. A wide variety of machine learning problems essentially minimize a regularized risk functional. We show that the proposed boosting framework, termed CGBoost, can accommodate various loss functions and different regularizers in a totally-corrective optimization fashion. We show that, by solving the primal rather than the dual, a large body of totally-corrective boosting algorithms can actually be efficiently solved and no sophisticated convex optimization solvers are needed. We also demonstrate that some boosting algorithms like AdaBoost can be interpreted in our framework--even their optimization is not totally corrective. We empirically show that various boosting algorithms based on the proposed framework perform similarly on the UCIrvine machine learning datasets [1] that we hav...

  14. Automatic Compensation of Total Phase Aberrations in Digital Holographic Biological Imaging

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yi-Zhuo; WANG Da-Yong; WANG Yun-Xin; TAO Shi-Quan

    2011-01-01

    Digital holographic microscopy has been a powerful metrological technique for phase-contrast imaging. However inherent phase aberrations always exist and degrade the quality of the phase-contrast images. A surface fitting method based on an improved mathematic model is proposed, which can be used to remove the phase aberrations without any pre-knowledge of the setup or manual operation. The improved mathematic model includes not only the usual terms but also the cross terms and the high order terms to describe the phase aberrations with high accuracy. Meanwhile, a non-iterative algorithm is used to solve the parametersand thus less computational load is imposed. The proposed method is applied to the live imaging of cells. The experimental results verify its validity.%Digital holographic microscopy has been a powerful metrological technique for phase-contrast imaging.However inherent phase aberrations always exist and degrade the quality of the phase-contrast images.A surface fitting method based on an improved mathematic model is proposed,which can be used to remove the phase aberrations without any pre-knowledge of the setup or manual operation.The improved mathematic model includes not only the usual terms but also the cross terms and the high order terms to describe the phase aberrations with high accuracy.Meanwhile,a non-iterative algorithm is used to solve the parametersand thus less computational load is imposed.The proposed method is applied to the live imaging of cells.The experimental results verify its validity.Digital holographic microscopy (DHM) has been a powerful metrological technique which permits realtime quantitative phase-contrast imaging.The hologram is recorded by a CCD or a CMOS camera while the reconstruction is performed numerically.Many digital signal processing techniques have been introduced to enhance DHM for speckle removal,[1,2] aperture truncation,[3] phase unwrapping[4,5] etc.It has been widely used in biomedical optics for

  15. 计及校正控制的安全约束最优潮流的奔德斯分解算法%Benders Decomposition Algorithm for Corrective Security-constrained Optimal Power Flow

    Institute of Scientific and Technical Information of China (English)

    钟世民; 韩学山; 刘道伟; 王孟夏

    2011-01-01

    针对电力系统调度、规划、检修及风险评估中反复涉及的校正控制安全约束最优潮流的求解问题,在深入机制分析基础上,提出一种基于奔德斯(Benders)分解与协调的模型和算法,使复杂大电网的求解得以进行.该模型和算法的主要贡献体现在:对正常状态下的最优潮流问题(也称主问题),基于电网关键元件规律特性的变动形成有效约束,以提高其求解效率;对预想事件(也称子问题)集,基于处于主导地位预想事件概念的有效筛选方法,使子问题数显著减少.由此,借用奔德斯分解的处理思想,实现主问题与子问题间的协调机制.最后以IEEE 30节点标准系统以及山东电网445节点实际系统作为算例,对该算法进行可行性、有效性等验证.%To solve the corrective security-constrained optimal power flow problem which is repeatedly involved in power system operation and economic dispatch, a practical approach based on Benders decomposition was proposed.So that the solution of complex and large power systems can be carried out.The approach is mainly reflected in: aiming at the optimal power flow problem under pre-contingency (also known as the Benders master problem), creates effective restraints based on the change characteristics of the key components of power system in order to improve the efficiency of its solution; for the post contingency (also called sub-problem) set, uses a contingency filtering method which can select the dominat contingencies, to reduce the number of sub-problems.As a result,using Benders decomposition algorithm realizes the coordination mechanism between the master problem and the sub-problems.In the end, the IEEE 30-bus system and the Shandong power grid 445-bus system demonstrates the feasibility and practicality of the proposed approach.

  16. Aberration measurement from specific photolithographic images: a different approach.

    Science.gov (United States)

    Nomura, H; Tawarayama, K; Kohno, T

    2000-03-01

    Techniques for measurement of higher-order aberrations of a projection optical system in photolithographic exposure tools have been established. Even-type and odd-type aberrations are independently obtained from printed grating patterns on a wafer by three-beam interference under highly coherent illumination. Even-type aberrations, i.e., spherical aberration and astigmatism, are derived from the best focus positions of vertical, horizontal, and oblique grating patterns by an optical microscope. Odd-type aberrations, i.e., coma and three-foil, are obtained by detection of relative shifts of a fine grating pattern to a large pattern by an overlay inspection tool. Quantitative diagnosis of lens aberrations with a krypton fluoride (KrF) excimer laser scanner is demonstrated.

  17. Aberration influenced generation of rotating two-lobe light fields

    Science.gov (United States)

    Kotova, S. P.; Losevsky, N. N.; Prokopova, D. V.; Samagin, S. A.; Volostnikov, V. G.; Vorontsov, E. N.

    2016-08-01

    The influence of aberrations on light fields with a rotating intensity distribution is considered. Light fields were generated with the phase masks developed using the theory of spiral beam optics. The effects of basic aberrations, such as spherical aberration, astigmatism and coma are studied. The experimental implementation of the fields was achieved with the assistance of a liquid crystal spatial light modulator HOLOEYE HEO-1080P, operating in reflection mode. The results of mathematical modelling and experiments have been qualitatively compared.

  18. Higher order aberrations of the eye: Part one

    Directory of Open Access Journals (Sweden)

    Marsha Oberholzer

    2016-03-01

    Full Text Available This article is the first in a series of two articles that provide a comprehensive literature review of higher order aberrations (HOAs of the eye. The present article mainly explains the general principles of such HOAs as well as HOAs of importance, and the measuring apparatus used to measure HOAs of the eye. The second article in the series discusses factors contributing to variable results in measurements of HOAs of the eye.Keywords: Higher order aberrations; wavefront aberrations; aberrometer

  19. Comparative study of visual acuity and aberrations after intralase femtosecond LASIK: small corneal flap versus big corneal flap

    Institute of Scientific and Technical Information of China (English)

    Ya-Li; Zhang; Lei; Liu; Chang-Xia; Cui; Ming; Hu; Zhao-Na; Li; Li-Jun; Cao; Xiu-Hua; Jing; Guo-Ying; Mu

    2014-01-01

    AIM:To study the effects of different flap sizes on visual acuity, refractive outcomes, and aberrations after femtosecond laser for laser keratomileusis (LASIK). ·METHODS: In each of the forty patients enrolled, 1 eye was randomly assigned to receive treatment with a 8.1mm diameter corneal flap, defined as the small flap, while the other eye was treated with a 8.6mm diameter corneal flap, defined as the big flap. Refractive errors, visual acuity, and higher -order aberrations were compared between the two groups at week 1, month 1 and 3 postoperatively. · RESULTS: The postoperative refractive errors and visual acuity all conformed to the intended goal. Postoperative higher -order aberrations were increased, especially in spherical aberration (Z12) and vertical coma (Z7). There were no statistically significant differences between the two groups in terms of postoperative refractive errors, visual acuity, root mean square of total HOAs (HO -RMS), trefoil 30° (Z6), vertical coma (Z7), horizontal coma (Z8), trefoil 0° (Z9), and spherical aberration (Z12) at any point during the postoperative follow-up. ·CONCLUSION: Both the small and big flaps are safe and effective procedures to correct myopia, provided the exposure stroma meets the excimer laser ablations. The personalized size corneal flap is feasible, as we can design the size of corneal flap based on the principle that the corneal flap diameter should be equal to or greater than the sum of the maximum ablation diameter and apparatus error.

  20. Cellular origin of prognostic chromosomal aberrations in AML patients

    DEFF Research Database (Denmark)

    Mora-Jensen, H.; Jendholm, J.; Rapin, N.;

    2015-01-01

    karyotype have demonstrated the presence of prognostic driver aberrations (that is, NPM1, FLT3-ITD and FLT3-TKD) in committed HPCs but not in multipotent HSCs. However, the HSC populations lacking the prognostic driver aberrations contained preleukemic clones harboring a series of recurrent molecular...... aberrations that were present in the fully transformed committed HPCs together with the prognostic driver aberration. Adding to this vast heterogeneity and complexity of AML genomes and their clonal evolution, a recent study of a murine AML model demonstrated that t(9;11) AML originating from HSCs responded...

  1. Chromosome aberration analysis for biological dosimetry: a review

    International Nuclear Information System (INIS)

    Among various biological dosimetry techniques, dicentric chromosome aberration method appears to be the method of choice in analysing accidental radiation exposure in most of the laboratories. The major advantage of this method is its sensitivity as the number of dicentric chromosomes present in control population is too small and more importantly radiation induces mainly dicentric chromosome aberration among unstable aberration. This report brings out the historical development of various cytogenetic methods, the basic structure of DNA, chromosomes and different forms of chromosome aberrations. It also highlights the construction of dose-response curve for dicentric chromosome and its use in the estimation of radiation dose. (author)

  2. Pileup correction of microdosimetric spectra

    CERN Document Server

    Langen, K M; Lennox, A J; Kroc, T K; De Luca, P M

    2002-01-01

    Microdosimetric spectra were measured at the Fermilab neutron therapy facility using low pressure proportional counters operated in pulse mode. The neutron beam has a very low duty cycle (<0.1%) and consequently a high instantaneous dose rate which causes distortions of the microdosimetric spectra due to pulse pileup. The determination of undistorted spectra at this facility necessitated (i) the modified operation of the proton accelerator to reduce the instantaneous dose rate and (ii) the establishment of a computational procedure to correct the measured spectra for remaining pileup distortions. In support of the latter effort, two different pileup simulation algorithms using analytical and Monte-Carlo-based approaches were developed. While the analytical algorithm allows a detailed analysis of pileup processes it only treats two-pulse and three-pulse pileup and its validity is hence restricted. A Monte-Carlo-based pileup algorithm was developed that inherently treats all degrees of pileup. This algorithm...

  3. Comparison of swarm intelligence algorithms in atmospheric compensation for free space optical communication

    Science.gov (United States)

    Li, Zhaokun; Cao, Jingtai; Liu, Wei; Feng, Jianfeng; Zhao, Xiaohui

    2015-03-01

    We use conventional adaptive optical system to compensate atmospheric turbulence in free space optical (FSO) communication system under strong scintillation circumstances, undesired wave-front measurements based on Shark-Hartman sensor (SH). Since wavefront sensor-less adaptive optics is a feasible option, we propose several swarm intelligence algorithms to compensate the wavefront aberration from atmospheric interference in FSO and mainly discuss the algorithm principle, basic flows, and simulation result. The numerical simulation experiment and result analysis show that compared with SPGD algorithm, the proposed algorithms can effectively restrain wavefront aberration, and improve convergence rate of the algorithms and the coupling efficiency of receiver in large extent.

  4. Spelling Correction in Agglutinative Languages

    CERN Document Server

    Oflazer, K

    1994-01-01

    This paper presents an approach to spelling correction in agglutinative languages that is based on two-level morphology and a dynamic programming based search algorithm. Spelling correction in agglutinative languages is significantly different than in languages like English. The concept of a word in such languages is much wider that the entries found in a dictionary, owing to {}~productive word formation by derivational and inflectional affixations. After an overview of certain issues and relevant mathematical preliminaries, we formally present the problem and our solution. We then present results from our experiments with spelling correction in Turkish, a Ural--Altaic agglutinative language. Our results indicate that we can find the intended correct word in 95\\% of the cases and offer it as the first candidate in 74\\% of the cases, when the edit distance is 1.

  5. Aberrant angiogenesis: The gateway to diabetic complications

    Directory of Open Access Journals (Sweden)

    Sunil K Kota

    2012-01-01

    Full Text Available Diabetes Mellitus is a metabolic cum vascular syndrome with resultant abnormalities in both micro- and macrovasculature. The adverse long-term effects of diabetes mellitus have been described to involve many organ systems. Apart from hyperglycemia, abnormalities of angiogenesis may cause or contribute toward many of the clinical manifestations of diabetes. These are implicated in the pathogenesis of vascular abnormalities of the retina, kidneys, and fetus, impaired wound healing, increased risk of rejection of transplanted organs, and impaired formation of coronary collaterals. A perplexing feature of the aberrant angiogenesis is that excessive and insufficient angiogenesis can occur in different organs in the same individual. The current article hereby reviews the molecular mechanisms including abnormalities in growth factors, cytokines, and metabolic derangements, clinical implications, and therapeutic options of dealing with abnormal angiogenesis in diabetes.

  6. Phase gradient algorithm method for three-dimensional holographic ladar imaging.

    Science.gov (United States)

    Stafford, Jason W; Duncan, Bradley D; Rabb, David J

    2016-06-10

    Three-dimensional (3D) holographic ladar uses digital holography with frequency diversity to add the ability to resolve targets in range. A key challenge is that since individual frequency samples are not recorded simultaneously, differential phase aberrations may exist between them, making it difficult to achieve range compression. We describe steps specific to this modality so that phase gradient algorithms (PGA) can be applied to 3D holographic ladar data for phase corrections across multiple temporal frequency samples. Substantial improvement of range compression is demonstrated with a laboratory experiment where our modified PGA technique is applied. Additionally, the PGA estimator is demonstrated to be efficient for this application, and the maximum entropy saturation behavior of the estimator is analytically described. PMID:27409018

  7. Statistical virtual eye model based on wavefront aberration

    OpenAIRE

    Wang, Jie-Mei; Liu, Chun-Ling; Luo, Yi-Ning; Liu, Yi-Guang; Hu, Bing-Jie

    2012-01-01

    Wavefront aberration affects the quality of retinal image directly. This paper reviews the representation and reconstruction of wavefront aberration, as well as the construction of virtual eye model based on Zernike polynomial coefficients. In addition, the promising prospect of virtual eye model is emphasized.

  8. Fifth-order aberrations in magnetic quadrupole-octupole systems

    International Nuclear Information System (INIS)

    Explicit integral expressions are given for the fifth-order geometrical aberration coefficients in rectilinear magnetic quadrupole-octupole systems used for the transport of nonrelativistic charged particle beams. The numerical values of the fifth-order geometrical aberration coefficients for a rare earth cobalt (REC) quadrupole doublet are given as an example. 26 refs., 5 figs., 4 tabs

  9. Expressions for third-order aberration theory for holographic images

    Indian Academy of Sciences (India)

    S K Tripathy; S Ananda Rao

    2003-01-01

    Expressions for third-order aberration in the reconstructed wave front of point objects are established by Meier. But Smith, Neil Mohon, Sweatt independently reported that their results differ from that of Meier. We found that coefficients for spherical aberration, astigmatism, tally with Meier’s while coefficients for distortion and coma differ.

  10. Chromosome aberration analysis based on a beta-binomial distribution

    International Nuclear Information System (INIS)

    Analyses carried out here generalized on earlier studies of chromosomal aberrations in the populations of Hiroshima and Nagasaki, by allowing extra-binomial variation in aberrant cell counts corresponding to within-subject correlations in cell aberrations. Strong within-subject correlations were detected with corresponding standard errors for the average number of aberrant cells that were often substantially larger than was previously assumed. The extra-binomial variation is accomodated in the analysis in the present report, as described in the section on dose-response models, by using a beta-binomial (B-B) variance structure. It is emphasized that we have generally satisfactory agreement between the observed and the B-B fitted frequencies by city-dose category. The chromosomal aberration data considered here are not extensive enough to allow a precise discrimination between competing dose-response models. A quadratic gamma ray and linear neutron model, however, most closely fits the chromosome data. (author)

  11. Brown's transport up to third order aberration by artificial intelligence

    International Nuclear Information System (INIS)

    Brown's TRANSPORT is a first and second order matrix multiplication computer program intended for the design of accelerator beam transport systems, neglecting the third order aberration. Recently a new method was developed to derive analytically any order aberration coefficients of general charged particle optic system, applicable to any practical systems, such as accelerators, electron microscopes, lithographs, including those unknown systems yet to be invented. An artificial intelligence program in Turbo Prolog was implemented on IBM-PC 286 or 386 machine to generate automatically the analytical expression of any order aberration coefficients of general charged particle optic system. Based on this new method and technique, Brown's TRANSPORT is extended beyond the second order aberration effect by artificial intelligence, outputting automatically all the analytical expressions up to the third order aberration coefficients

  12. Chromatic aberration and the roles of double-opponent and color-luminance neurons in color vision.

    Science.gov (United States)

    Vladusich, Tony

    2007-03-01

    How does the visual cortex encode color? I summarize a theory in which cortical double-opponent color neurons perform a role in color constancy and a complementary set of color-luminance neurons function to selectively correct for color fringes induced by chromatic aberration in the eye. The theory may help to resolve an ongoing debate concerning the functional properties of cortical receptive fields involved in color coding.

  13. An unusual case of left aberrant innominate artery with right aortic arch: evaluation with high-resolution CT

    Energy Technology Data Exchange (ETDEWEB)

    Calcagni, Giulio [University Rene Descartes-Paris 5, Department of Pediatric Cardiology, Hopital Necker Enfants Malades, Paris (France); Gesualdo, Francesco; Brunelle, Francis; Ou, Phalla [University Rene Descartes-Paris 5, Department of Pediatric Radiology, Hopital Necker Enfants Malades, Paris Cedex 15 (France)

    2008-01-15

    A left aberrant innominate (brachiocephalic) artery is an angiographically well-known entity that may cause tracheal compression. We report a male newborn who was admitted for further investigation of a prenatally suspected major vessel anomaly. High-resolution CT was used to completely assess the abnormal anatomy and the relationship with the airway, as well as to guide the surgical approach for its correction. (orig.)

  14. Wavelet-based denoising of the Fourier metric in real-time wavefront correction for single molecule localization microscopy

    Science.gov (United States)

    Tehrani, Kayvan Forouhesh; Mortensen, Luke J.; Kner, Peter

    2016-03-01

    Wavefront sensorless schemes for correction of aberrations induced by biological specimens require a time invariant property of an image as a measure of fitness. Image intensity cannot be used as a metric for Single Molecule Localization (SML) microscopy because the intensity of blinking fluorophores follows exponential statistics. Therefore a robust intensity-independent metric is required. We previously reported a Fourier Metric (FM) that is relatively intensity independent. The Fourier metric has been successfully tested on two machine learning algorithms, a Genetic Algorithm and Particle Swarm Optimization, for wavefront correction about 50 μm deep inside the Central Nervous System (CNS) of Drosophila. However, since the spatial frequencies that need to be optimized fall into regions of the Optical Transfer Function (OTF) that are more susceptible to noise, adding a level of denoising can improve performance. Here we present wavelet-based approaches to lower the noise level and produce a more consistent metric. We compare performance of different wavelets such as Daubechies, Bi-Orthogonal, and reverse Bi-orthogonal of different degrees and orders for pre-processing of images.

  15. Atmospheric correction of CBERS CCD images with MODIS data

    Institute of Scientific and Technical Information of China (English)

    LI Junsheng; ZHANG Bing; CHEN Zhengchao; SHEN Qian

    2006-01-01

    China Brazil Earth Resource Satellite (CBERS) CCD images have much potential for inland water environmental monitoring. However, their atmospheric accuracy correction can affect their quantitative applications. This paper contains an atmospheric correction algorithm for CBERS CCD images with MODIS data from the same day, the use of which improves the atmospheric correction algorithm of ocean color remote sensing developed by Gordon (1993, 1994) and makes it applicable to inland waters. The improved algorithm retrieves atmospheric parameters from MODIS data and uses them to perform the atmospheric correction of CBERS CCD images. Experimental results show that the atmospheric correction algorithm of CBERS CCD images assisted by MODIS data is reliable. Furthermore, MODIS data can be freely obtained on a daily basis, making the algorithm developed in this paper useful for environmental monitoring of inland waters.

  16. Error Bit Correction of ECC Attack Based on Grover Quantum Intermediate Encounter Search Algorithm%基于Grover量子中间相遇搜索算法的ECC攻击错误bit的修正

    Institute of Scientific and Technical Information of China (English)

    贾徽徽; 王潮; 顾健; 陆臻

    2016-01-01

    The existing error bit in the side channel attacks of ECC is difficult to avoid, and can’t be modiifed quickly. In this paper, a new search algorithm based on the Grover quantum search algorithm is proposed, which combines the Grover quantum search algorithm and the meet in the middle attack, and applies it to the side channel attack for ECC. The algorithm can solve the key problem ofn which hasM error bit inO steps. Compared with classical search algorithm, the computational complexity is greatly reduced. The analysis said that the success rate of modifying ECC attack error bit is 1, and the algorithm can effectively reduce the computational complexity.%在现有的针对ECC的侧信道攻击中,密钥出现错误bit难以避免,且无法快速修正。文章将Grover量子搜索算法和中间相遇攻击相结合,提出了一种新的搜索算法——Grover量子中间相遇搜索算法,并将其应用于针对ECC的侧信道攻击中。该算法可以在O规模为N且存在M个错误bit的密钥,与传统搜索算法的计算复杂度O(N M+1)相比较,计算复杂度大幅度降低。通过对算法进行分析表明,该方法能够以成功率1修正ECC攻击中出现的错误bit。

  17. Large-volume optical coherence tomography with real-time correction of geometric distortion artifacts

    CERN Document Server

    Van der Jeught, Sam; Bradu, Adrian; Podoleanu, Adrian Gh; Dirckx, Joris J J

    2012-01-01

    Large-volume optical coherence tomography (OCT)-setups employ scanning mirrors and suffer from non-linear geometric distortion artifacts in which the degree of distortion is determined by the maximum angles over which the mirrors rotate. In this chapter, we describe a straightforward approach to correct for these distortion artifacts, creating an alternative to previously reported ray-tracing schemes that are unable to apply these corrections in real-time. By implementing the proposed 3D recalibration algorithm on the graphics card of a standard computer, this feature can be applied in real-time. We validate the accuracy of the technique using OCT measurements of a highly curved object within a large imaging volume of 12.35 x 10.13 x 2.36 mm^3. The resulting 3D object shape measurements are compared against high-resolution and aberration-free optical profilometry measurements. Maintaining an optical resolution of <10 micron within the sample, both axially and transversally, we realized a real-time, high-re...

  18. Chromosome aberrations in solid tumors have a stochastic nature

    Energy Technology Data Exchange (ETDEWEB)

    Castro, Mauro A.A. [Departamento de Bioquimica, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-anexo, Porto Alegre 90035-003 (Brazil) and Departamento de Medicina Interna, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2350, Porto Alegre 90035-903 (Brazil) and Instituto de Fisica, Universidade Federal do Rio Grande do Sul, Av. Bento Goncalves 9500, Porto Alegre 91501-970 (Brazil) and Universidade Luterana do Brasil, Rua Miguel Tostes 101, Canoas 92420-280 (Brazil)]. E-mail: mauro@ufrgs.br; Onsten, Tor G.H. [Departamento de Medicina Interna, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2350, Porto Alegre 90035-903 (Brazil); Universidade Luterana do Brasil, Rua Miguel Tostes 101, Canoas 92420-280 (Brazil); Moreira, Jose C.F. [Departamento de Bioquimica, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-anexo, Porto Alegre 90035-003 (Brazil); Almeida, Rita M.C. de [Instituto de Fisica, Universidade Federal do Rio Grande do Sul, Av. Bento Goncalves 9500, Porto Alegre 91501-970 (Brazil)

    2006-08-30

    An important question nowadays is whether chromosome aberrations are random events or arise from an internal deterministic mechanism, which leads to the delicate task of quantifying the degree of randomness. For this purpose, we have defined several Shannon information functions to evaluate disorder inside a tumor and between tumors of the same kind. We have considered 79 different kinds of solid tumors with 30 or more karyotypes retrieved from the Mitelman Database of Chromosome Aberrations in Cancer. The Kaplan-Meier cumulative survival was also obtained for each solid tumor type in order to correlate data with tumor malignance. The results here show that aberration spread is specific for each tumor type, with high degree of diversity for those tumor types with worst survival indices. Those tumor types with preferential variants (e.g. high proportion of a given karyotype) have shown better survival statistics, indicating that aberration recurrence is a good prognosis. Indeed, global spread of both numerical and structural abnormalities demonstrates the stochastic nature of chromosome aberrations by setting a signature of randomness associated to the production of disorder. These results also indicate that tumor malignancy correlates not only with karyotypic diversity taken from different tumor types but also taken from single tumors. Therefore, by quantifying aberration spread, we could confront diverse models and verify which of them points to the most likely outcome. Our results suggest that the generating process of chromosome aberrations is neither deterministic nor totally random, but produces variations that are distributed between these two boundaries.

  19. Epigenetic aberrations and therapeutic implications in gliomas.

    Science.gov (United States)

    Natsume, Atsushi; Kondo, Yutaka; Ito, Motokazu; Motomura, Kazuya; Wakabayashi, Toshihiko; Yoshida, Jun

    2010-06-01

    Almost all cancer cells have multiple epigenetic abnormalities, which combine with genetic changes to affect many cellular processes, including cell proliferation and invasion, by silencing tumor-suppressor genes. In this review, we focus on the epigenetic mechanisms of DNA hypomethylation and CpG island hypermethylation in gliomas. Aberrant hypermethylation in promoter CpG islands has been recognized as a key mechanism involved in the silencing of cancer-associated genes and occurs at genes with diverse functions related to tumorigenesis and tumor progression. Such promoter hypermethylation can modulate the sensitivity of glioblastomas to drugs and radiotherapy. As an example, the methylation of the O6-methylguanine DNA methyltransferase (MGMT) promoter is a specific predictive biomarker of tumor responsiveness to chemotherapy with alkylating agents. Further, we reviewed reports on pyrosequencing - a simple technique for the accurate and quantitative analysis of DNA methylation. We believe that the quantification of MGMT methylation by pyrosequencing might enable the selection of patients who are most likely to benefit from chemotherapy. Finally, we also evaluated the potential of de novo NY-ESO-1, the most immunogenic cancer/testis antigen (CTA) discovered thus far, as an immunotherapy target. The use of potent epigenetics-based therapy for cancer cells might restore the abnormally regulated epigenomes to a more normal state through epigenetic reprogramming. Thus, epigenetic therapy may be a promising and potent treatment for human neoplasia.

  20. Aberrant DNA methylation in cloned ovine embryos

    Institute of Scientific and Technical Information of China (English)

    LIU Lei; HOU Jian; LEI TingHua; BAI JiaHua; GUAN Hong; AN XiaoRong

    2008-01-01

    By using the approach of immunofluorescence staining with an antibody against 5-methylcytosine (5MeC), the present study detected the DNA methylation patterns of cloned ovine embryos. The em-bryos derived from in vitro fertilization were also examined for reference purpose. The results showed that: (1) during the pre-implantation development, cloned embryos displayed a similar demethylation profile to the fertilized embryos; that is, the methylation level decreased to the lowest at 8-cell stage, and then increased again at morulae stage. However, methylation level was obviously higher in cloned embryos than in stage-matched fertilized embryos, especially at 8-cell stage and afterwards; (2) at blastocyst stage, the methylation pattern in cloned embryos was different from that in fertilized em-bryos. In cloned blastocyst, inner cell mass (ICM) exhibited a comparable level to trophectoderm cells (TE), while in in-vitro fertilized blastocyst the methylation level of ICM was lower than that of TE, which is not consistent with that reported by other authors. These results indicate that DNA methylation is abnormally reprogrammed in cloned embryos, implying that aberrant DNA methylation reprogramming may be one of the factors causing cloned embryos developmental failure.

  1. Formal verification of a deadlock detection algorithm

    Directory of Open Access Journals (Sweden)

    Freek Verbeek

    2011-10-01

    Full Text Available Deadlock detection is a challenging issue in the analysis and design of on-chip networks. We have designed an algorithm to detect deadlocks automatically in on-chip networks with wormhole switching. The algorithm has been specified and proven correct in ACL2. To enable a top-down proof methodology, some parts of the algorithm have been left unimplemented. For these parts, the ACL2 specification contains constrained functions introduced with defun-sk. We used single-threaded objects to represent the data structures used by the algorithm. In this paper, we present details on the proof of correctness of the algorithm. The process of formal verification was crucial to get the algorithm flawless. Our ultimate objective is to have an efficient executable, and formally proven correct implementation of the algorithm running in ACL2.

  2. Formal verification of a deadlock detection algorithm

    CERN Document Server

    Verbeek, Freek; 10.4204/EPTCS.70.8

    2011-01-01

    Deadlock detection is a challenging issue in the analysis and design of on-chip networks. We have designed an algorithm to detect deadlocks automatically in on-chip networks with wormhole switching. The algorithm has been specified and proven correct in ACL2. To enable a top-down proof methodology, some parts of the algorithm have been left unimplemented. For these parts, the ACL2 specification contains constrained functions introduced with defun-sk. We used single-threaded objects to represent the data structures used by the algorithm. In this paper, we present details on the proof of correctness of the algorithm. The process of formal verification was crucial to get the algorithm flawless. Our ultimate objective is to have an efficient executable, and formally proven correct implementation of the algorithm running in ACL2.

  3. The Compact Hyperspectral Aberration-corrected Platform (CHAP), an instrument for microspacecraft. Project

    Data.gov (United States)

    National Aeronautics and Space Administration — In-situ analysis of solar system bodies plays a crucial role in understanding the evolution of our planet, setting the stage for life's origins. As has been...

  4. Therapeutic efficacy by targeting correction of Notch1-induced aberrants in uveal tumors.

    Directory of Open Access Journals (Sweden)

    Xiaolin Huang

    Full Text Available There is a need for more effective treatments for uveal melanoma. The recombinant oncolytic adenovirus H101 replicates specifically in p53-depleted tumor cells, and has been approved for use by the Chinese State Food and Drug Administration. However, this treatment is associated with subsequent remission. Transfection of uveal melanoma cells with a small interfering RNA against Notch1 (siNotch1 effectively suppressed Notch1 expression, resulting in significant cell growth inhibition when combined with H101 treatment. Combined treatment with siNotch1 and H101 (H101-Notch1-siRNA greatly enhanced apoptosis and cell cycle arrest in vitro as compared to treatment with H101 or siNotch1 alone. For in vivo treatments, the combined treatment of siNotch1 and H101 showed remarkable tumor growth inhibition and prolonged mouse survival in the OCM1 xenograft model. We predict that Notch pathway deregulation could be a feature of uveal melanoma, and could be a therapeutic target, especially if p53 is concurrently targeted.

  5. Atom-column distinction by Kikuchi pattern observed by an aberration-corrected convergent electron probe.

    Science.gov (United States)

    Saitoh, Koh; Tatara, Yoshihide; Tanaka, Nobuo

    2010-01-01

    Kikuchi patterns of an MgO crystal at the [110] incidence have been taken by a sub-angstrom electron beam focused on the single atom-column. A significant change in intensity has been observed in the 111 band; that is, the contrast in the central and side bands is reversed depending on the illuminated atom-column. The contrast reversal in the 111 band has been reproduced by multislice simulation using the frozen-phonon approach. The beam-position dependence of the 111 band intensity can be interpreted by electron channelling and the reciprocity theorem. The anomalous Kikuchi pattern can be a probe for identifying the illuminated atom-column, which is useful for column-by-column electron energy-loss spectroscopy and X-ray emission spectroscopy.

  6. Chromatic aberration correction and deconvolution for UV sensitive imaging of fluorescent sterols in cytoplasmic lipid droplets

    DEFF Research Database (Denmark)

    Wüstner, Daniel; Faergeman, Nils J

    2008-01-01

    Intrinsically fluorescent sterols, like dehydroergosterol (DHE), mimic cholesterol closely and are therefore suitable to determine cholesterol transport by fluorescence microscopy. Disadvantages of DHE are its low quantum yield, rapid bleaching, and the fact that its excitation and emission...... adipocyte differentiation. DHE is targeted to transferrin-positive recycling endosomes in preadipocytes but associates with droplets in mature adipocytes. Only in adipocytes but not in foam cells fluorescent sterol was confined to the droplet-limiting membrane. We developed an approach to visualize...... and quantify sterol content of lipid droplets in living cells with potential for automated high content screening of cellular sterol transport....

  7. Algorithmic cryptanalysis

    CERN Document Server

    Joux, Antoine

    2009-01-01

    Illustrating the power of algorithms, Algorithmic Cryptanalysis describes algorithmic methods with cryptographically relevant examples. Focusing on both private- and public-key cryptographic algorithms, it presents each algorithm either as a textual description, in pseudo-code, or in a C code program.Divided into three parts, the book begins with a short introduction to cryptography and a background chapter on elementary number theory and algebra. It then moves on to algorithms, with each chapter in this section dedicated to a single topic and often illustrated with simple cryptographic applic

  8. Aberrations of Genetic Material as Biomarkers of Ionizing Radiation Effects

    Energy Technology Data Exchange (ETDEWEB)

    Milacic, S.

    2004-07-01

    Ionizing radiation is the most powerful mutagen in environmental and working conditions. The result of genotoxic effect of radiation is the development of chromosome aberrations. The structural chromosome aberrations in peripheral blood lymphocytes are dicentric, ring, acentric fragment. The observation of chromosome aberration frequency in lymphocyte karyotype is the conclusive method to assess the absorbed dose of ionizing radiation. Our study compared the incidence of chromosome aberrations in occupationally exposed healthy medical workers and in non-exposed healthy population. We analyzed the effect of working place, dose by thermo luminescence personal dosimeter (TLD), duration of occupational exposure (DOE) and age to the sum of aberrant cells and aberrations. four-year study included 462 subjects, mean-aged 42.3 years, who were occupational exposed to ionizing radiation and 95 subjects, mean-aged 35,2 years, who were not exposed to ionizing radiation, during the same time period and from the same territory. All of them possess thermo luminescence personal dosimeter (TLD) which is read by scanner for thermo luminescence dosimeters. Modified Moorheard's micro method for peripheral blood lymphocytes and conventional cytogenetic technique of chromosome aberration analysis were used for analysis of chromosome aberrations. Stained preparations (Giemsa) are observed in immersion by light microscope. The karyotype of 200 lymphocytes in metaphase is analyzed the most characteristic aberration: dicentric, then the ring and acentric fragments. The increased incidence of chromosome aberrations was found to tbe 21.6% in the exposed group and 2.1% in the controls, while the findings within the limits (non-specific chromosome lesions-gaps breaks, elongations, and exchanges) were equal in both groups (22%). Among occupationally exposed medical workers, the highest incidence was found in nuclear medicine workers (42.6%), then in orthopedists (27.08%). There is highly

  9. Comparative study of pressure-correction and Godunov-type schemes on unsteady compressible cases

    OpenAIRE

    Archambeau, Frédéric; Hérard, Jean-Marc; Laviéville, Jérôme

    2009-01-01

    Two pressure-correction algorithms are studied and compared to an approximate Godunov scheme on unsteady compressible cases. The first pressure-correction algorithm sequentially solves the equations for momentum, mass and enthalpy, with sub-iterations which ensure conservativity. The algorithm also conserves the total enthalpy along a streamline, in a steady flow. The second pressure-correction algorithm sequentially solves the equations for mass, momentum and energy without sub-iteration. Th...

  10. 77 FR 72199 - Technical Corrections; Correction

    Science.gov (United States)

    2012-12-05

    ...) is correcting a final rule that was published in the Federal Register on July 6, 2012 (77 FR 39899), and effective on August 6, 2012. That final rule amended the NRC regulations to make technical... COMMISSION 10 CFR Part 171 RIN 3150-AJ16 Technical Corrections; Correction AGENCY: Nuclear...

  11. Algorithmic mathematics

    CERN Document Server

    Hougardy, Stefan

    2016-01-01

    Algorithms play an increasingly important role in nearly all fields of mathematics. This book allows readers to develop basic mathematical abilities, in particular those concerning the design and analysis of algorithms as well as their implementation. It presents not only fundamental algorithms like the sieve of Eratosthenes, the Euclidean algorithm, sorting algorithms, algorithms on graphs, and Gaussian elimination, but also discusses elementary data structures, basic graph theory, and numerical questions. In addition, it provides an introduction to programming and demonstrates in detail how to implement algorithms in C++. This textbook is suitable for students who are new to the subject and covers a basic mathematical lecture course, complementing traditional courses on analysis and linear algebra. Both authors have given this "Algorithmic Mathematics" course at the University of Bonn several times in recent years.

  12. Impact of primary aberrations on coherent lidar performance

    DEFF Research Database (Denmark)

    Hu, Qi; Rodrigo, Peter John; Iversen, Theis Faber Quist;

    2014-01-01

    In this work we investigate the performance of a monostatic coherent lidar system in which the transmit beam is under the influence of primary phase aberrations: spherical aberration (SA) and astigmatism. The experimental investigation is realized by probing the spatial weighting function...... of the lidar system using different optical transceiver configurations. A rotating belt is used as a hard target. Our study shows that the lidar weighting function suffers from both spatial broadening and shift in peak position in the presence of aberration. It is to our knowledge the first experimental...... effciency, the optimum truncation of the transmit beam and the spatial sensitivity of a CW coherent lidar system. Under strong degree of aberration, the spatial confinement is significantly degraded. However for SA, the degradation of the spatial confinement can be reduced by tuning the truncation...

  13. Chromosome aberrations in pesticide-exposed greenhouse workers

    DEFF Research Database (Denmark)

    Lander, B F; Knudsen, Lisbeth E.; Gamborg, M O;

    2000-01-01

    OBJECTIVES: The aim of this study was to investigate the possibility of subtoxic exposure to pesticides causing chromosome aberrations in greenhouse workers. METHODS: In a cross-sectional and prospective study design chromosome aberration frequencies in cultured lymphocytes were examined for 116...... greenhouse workers exposed to a complex mixture of almost 50 insecticides, fungicides, and growth regulators and also for 29 nonsmoking, nonpesticide-exposed referents. RESULTS: The preseason frequencies of chromosome aberrations were slightly but not statistically significantly elevated for the greenhouse...... workers when they were compared with the referents. After a summer season of pesticide spraying in the greenhouses, the total frequencies of cells with chromosome aberrations were significantly higher than in the preseason samples (P=0.02) and also higher than for the referents (P=0.05). This finding...

  14. Aberrant internal carotid artery in the middle ear

    Energy Technology Data Exchange (ETDEWEB)

    Roh, Keun Tak; Kang, Hyun Koo [Dept. of Radiology, Seoul Veterans Hospital, Seoul (Korea, Republic of)

    2014-10-15

    The knowledge about the aberrant internal carotid artery (ICA) in the middle ear is essential for clinicians, because a misdiagnosis of the aberrant ICA could have serious consequences such as excessive aural bleeding during a middle ear surgery. A 38-year-old woman presented with tinnitus and hearing difficulties of the left ear that had started 5 years ago. During otoscopy, an anteroinferior bluish mass was seen in the tympanic space. Computed tomography and magnetic resonance imaging demonstrated a left-side aberrant ICA with bony dehiscence of the carotid canal in the middle ear and a reduced diameter of the tympanic ICA. Herein we report a case of an aberrant ICA in the middle ear. We also review the literature regarding this important vascular anomaly of the temporal bone which may lead to disastrous surgical complications.

  15. CT of ruptured aneurysm of aberrant right subclavian artery.

    Science.gov (United States)

    Vega, A; Ortíz, A; Longo, J M; Pagola, M A

    1987-01-01

    This paper presents the first description of a ruptured aneurysm of an aberrant right subclavian artery. CT clearly demonstrated the vascular malformation as well as the existence of a bilateral hemothorax. PMID:3102065

  16. Total algorithms

    NARCIS (Netherlands)

    Tel, G.

    1993-01-01

    We define the notion of total algorithms for networks of processes. A total algorithm enforces that a "decision" is taken by a subset of the processes, and that participation of all processes is required to reach this decision. Total algorithms are an important building block in the design of distri

  17. moco: Fast Motion Correction for Calcium Imaging

    Directory of Open Access Journals (Sweden)

    Alexander eDubbs

    2016-02-01

    Full Text Available Motion correction is the first step in a pipeline of algorithms to analyze calcium imaging videos and extract biologically relevant information, for example the network structure of the neurons therein. Fast motion correction is especially critical for closed-loop activity triggered stimulation experiments, where accurate detection and targeting of specific cells in necessary. We introduce a novel motion-correction algorithm that uses a Fourier-transform approach, and a combination of judicious downsampling and the accelerated computation of many $L_2$ norms using dynamic programming and two-dimensional, fft-accelerated convolutions, to enhance its efficiency. Its accuracy is comparable to that of established community-used algorithms, and it is more stable to large translational motions. It is programmed in Java and is compatible with ImageJ.

  18. moco: Fast Motion Correction for Calcium Imaging.

    Science.gov (United States)

    Dubbs, Alexander; Guevara, James; Yuste, Rafael

    2016-01-01

    Motion correction is the first step in a pipeline of algorithms to analyze calcium imaging videos and extract biologically relevant information, for example the network structure of the neurons therein. Fast motion correction is especially critical for closed-loop activity triggered stimulation experiments, where accurate detection and targeting of specific cells in necessary. We introduce a novel motion-correction algorithm which uses a Fourier-transform approach, and a combination of judicious downsampling and the accelerated computation of many L 2 norms using dynamic programming and two-dimensional, fft-accelerated convolutions, to enhance its efficiency. Its accuracy is comparable to that of established community-used algorithms, and it is more stable to large translational motions. It is programmed in Java and is compatible with ImageJ.

  19. Moment aberrations in magneto-electrostatic plasma lenses (computer simulation)

    CERN Document Server

    Butenko, V I

    2001-01-01

    In this work moment aberrations in the plasma magneto-electrostatic lenses are considered in more detail with the use of the computer modeling. For solution of the problem we have developed a special computer code - the model of plasma optical focusing device, allowing to display the main parameters and operations of experimental sample of a lens, to simulate the moment and geometrical aberrations and give recommendations on their elimination.

  20. Photothermal Lens Aberration Effects in Two Laser Thermal Lens Spectrometry

    OpenAIRE

    Bialkowski, Stephen E.

    1985-01-01

    A comparison of theories describing two laser photothermal lens signals is given. The aberrant nature of this lens is accounted for in a theory which treats the propagation of a monitor laser in terms of a phase shift in this laser beam wave front. The difference between theories are discussed in terms of the predicted signal strengths and temporal behavior. The aberrant theory results in smaller theoretical signal strengths and different functional relationships between signal and analyte le...

  1. Aberrant cervical thymus mimicking thyroid on ultrasonography: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeong Sub; Park, Ju Hyun; Kim, Bong Soo; Park, Ji Kang; Choi, Jae Hyuck [Jeju National Univ. Hospital/Jeju National Univ. School of Medicine, Jeju (Korea, Republic of)

    2012-10-15

    Aberrant cervical thymus is rarely reported in adults. We report a case of solid aberrant cervical thymus in a 27 year old female, which was found incidentally on ultrasonography for the evaluation of the thyroid cancer. On ultrasonography, the lesion was found between the left thyroid and common carotid artery without any remarkable interface echo, and had similar echogenicity to the thyroid. The lesion extended to the upper pole of the left thyroid.

  2. Dimensions of driving anger and their relationships with aberrant driving.

    Science.gov (United States)

    Zhang, Tingru; Chan, Alan H S; Zhang, Wei

    2015-08-01

    The purpose of this study was to investigate the relationship between driving anger and aberrant driving behaviours. An internet-based questionnaire survey was administered to a sample of Chinese drivers, with driving anger measured by a 14-item short Driving Anger Scale (DAS) and the aberrant driving behaviours measured by a 23-item Driver Behaviour Questionnaire (DBQ). The results of Confirmatory Factor Analysis demonstrated that the three-factor model (hostile gesture, arrival-blocking and safety-blocking) of the DAS fitted the driving anger data well. The Exploratory Factor Analysis on DBQ data differentiated four types of aberrant driving, viz. emotional violation, error, deliberate violation and maintaining progress violation. For the anger-aberration relation, it was found that only "arrival-blocking" anger was a significant positive predictor for all four types of aberrant driving behaviours. The "safety-blocking" anger revealed a negative impact on deliberate violations, a finding different from previously established positive anger-aberration relation. These results suggest that drivers with different patterns of driving anger would show different behavioural tendencies and as a result intervention strategies may be differentially effective for drivers of different profiles.

  3. The Simulation Research of Magnetic Encoder Angle Error Correction Based on Improved CORDIC Algorithm%基于 CORDIC 算法的磁编码器角度误差修正仿真研究

    Institute of Scientific and Technical Information of China (English)

    薛凌云; 孙世荣

    2016-01-01

    The coordinate rotation digital compute (CORDIC ) algorithm is widely used in magnetic rotary encoder ,because of the noise and non‐orthogonal signal caused by encoder manufacturing and installation process , classic CORDIC algorithm has a big output angle error . This paper uses MATLAB simulation to produce the rotating magnetic field signals with noise signal . Firstly the signals should be processed by the mean value filter ,next according to the feature that angle error curve approximates the sine and cosine functions ,using CORDIC algorithm to process the value of the input signal ,and then shift the phase and again using the CORDIC algorithm to process the value of the input signal , finally deal with the difference between the results of two CORDIC algorithm processing .The simulation results show that the output angle error is between ‐0 .25°to 0 .25° ,so it effectively reduced the angle detection error ,and improved the angle detection accuracy .%CORDIC 算法在磁旋转编码器中被广泛使用,但受编码器制造与安装工艺所带来的噪声和信号非正交性的影响,经典 CORDIC 算法存在较大输出角度误差.采用 MATLAB 模拟产生含噪旋转磁场信号,首先对信号进行均值滤波,再根据角度误差曲线近似于正余弦函数的特点,对输入信号值运用 CORDIC 算法处理,然后对输入信号值移相后再运用 CORDIC 算法处理,并对两次CORDIC 算法结果进行差值处理,最终获得磁编码器输出角度值.仿真结果表明,输出角度的误差在-0.25°~0.25°之间,有效减少了角度检测误差,提高了角度检测精度.

  4. Implementation of Cryptographic Algorithm on FPGA

    OpenAIRE

    Prof. S. Venkateswarlu; Deepa G.M; G. Sriteja

    2013-01-01

    Advanced Encryption Standard (AES), a Federal Information Processing Standard (FIPS), is anapproved cryptographic algorithm that is used to protect electronic data. The AES can be programmed insoftware or built with hardware. The paper presents a hardware implementation of the AES algorithm onFPGA. The algorithm was implemented in FPGA using Spartan 3E starter kit and Xilinx ISE developmentsuite. The purpose of this attempt was to test the correctness of the implemented algorithm and to gaine...

  5. Corrected Co-training for Statistical Parsers

    OpenAIRE

    Hwa, Rebecca; Osborne, Miles; Sarkar, Anoop; Steedman, Mark

    2003-01-01

    Corrected co-training (Pierce & Cardie, 2001) and the closely related co-testing (Muslea et al., 2000) are active learning methods which exploit redundant views to reduce the cost of manually creating labeled training data. We extend these methods to statistical parsing algorithms for natural language. Because creating complex parse structures by hand is significantly more timeconsuming than selecting labels from a small set, it may be easier for the human to correct the learner’s partial...

  6. Performance of TPC crosstalk correction

    CERN Document Server

    Dydak, F; Krasnoperov, A; Nefedov, Y; Wotschack, J; Zhemchugov, A

    2004-01-01

    The performance of the CERN-Dubna-Milano (CDM) algorithm for TPC crosstalk correction is presented. The algorithm is designed to correct for uni-directional and bi-directional crosstalk, but not for self-crosstalk. It reduces at the 10% level the number of clusters, and the number of pads with a signal above threshold. Despite of dramatic effects in selected channels with complicated crosstalk patterns, the average longitudinal signal shape of a hit, and the average transverse signal shape of a cluster, are little affected by uni-directional and bi-directional crosstalk. The longitudinal signal shape of hits is understood in terms of preamplifier response, longitudinal diffusion, track inclination, and self-crosstalk. The transverse signal shape of clusters is understood in terms of the TPC's pad response function. The CDM crosstalk correction leads to an average charge decrease at the level of 15%, though with significant differences between TPC sectors. On the whole, crosstalk constitutes a relatively benig...

  7. Persistence of Early Emerging Aberrant Behavior in Children with Developmental Disabilities

    Science.gov (United States)

    Green, Vanessa A.; O'Reilly, Mark; Itchon, Jonathan; Sigafoos, Jeff

    2005-01-01

    This study examined the persistence of early emerging aberrant behavior in 13 preschool children with developmental disabilities. The severity of aberrant behavior was assessed every 6 months over a 3-year period. Teachers completed the assessments using the Aberrant Behavior Checklist [Aman, M. G., & Singh, N. N. (1986). "Aberrant Behavior…

  8. Optical aberrations of intraocular lenses measured in vivo and in vitro

    Science.gov (United States)

    Barbero, Sergio; Marcos, Susana; Jiménez-Alfaro, Ignacio

    2003-10-01

    Corneal and ocular aberrations were measured in a group of eyes before and after cataract surgery with spherical intraocular lens (IOL) implantation by use of well-tested techniques developed in our laboratory. By subtraction of corneal from total aberration maps, we also estimated the optical quality of the intraocular lens in vivo. We found that aberrations in pseudophakic eyes are not significantly different from aberrations in eyes before cataract surgery or from previously reported aberrations in healthy eyes of the same age. However, aberrations in pseudophakic eyes are significantly higher than in young eyes. We found a slight increase of corneal aberrations after surgery. The aberrations of the IOL and the lack of balance of the corneal spherical aberrations by the spherical aberrations of the intraocular lens also degraded the optical quality in pseudophakic eyes. We also measured the aberrations of the IOL in vitro, using an eye cell model, and simulated the aberrations of the IOL on the basis of the IOL's physical parameters. We found a good agreement among in vivo, in vitro, and simulated measures of spherical aberration: Unlike the spherical aberration of the young crystalline lens, which tends to be negative, the spherical aberration of the IOL is positive and increases with lens power. Computer simulations and in vitro measurements show that tilts and decentrations might be contributors to the increased third-order aberrations in vivo in comparison with in vitro measurements.

  9. Evaluation of the Analytical Anisotropic Algorithm (AAA) in dose calculation for fields with non-uniform fluences considering heterogeneity correction; Avaliacao do Algoritmo Analitico Anisotropico (AAA) no calculo de dose para campos com fluencia nao uniforme considerando correcao de heterogeneidade

    Energy Technology Data Exchange (ETDEWEB)

    Bornatto, P.; Funchal, M.; Bruning, F.; Toledo, H.; Lyra, J.; Fernandes, T.; Toledo, F.; Marciao, C., E-mail: pricila_bornatto@yahoo.com.br [Hospital Erasto Gaertner (LPCC), Curitiba, PR (Brazil). Departamento de Radioterapia

    2014-08-15

    The purpose of this study is to evaluate the calculation of dose distribution AAA (Varian Medical Systems) for fields with non-uniform fluences considering heterogeneity correction. Five different phantoms were used with different density materials. These phantoms were scanned in the CT BrightSpeed (©GE Healthcare) upon the array of detectors MAPCHECK2 TM (Sun Nuclear Corporation) and irradiated in a linear accelerator 600 CD (Varian Medical Systems) 6MV and rate dose 400MU/min with isocentric setup. The fluences used were exported from IMRT plans, calculated by ECLIPSE™ planning system (Varian Medical Systems), and a 10x10 cm{sup 2} field to assess the heterogeneity correction for uniform fluence. The measured dose distribution was compared to the calculated by Gamma analysis with approval criteria of 3% / 3 mm and 10% threshold. The evaluation was performed using the software SNCPatient (Sun Nuclear Corporation) and considering absolute dose normalized at maximum. The phantoms best performers were those with low density materials, with an average of 99.2% approval. Already phantoms with plates of higher density material presented various fluences below 95% of the points approved. The average value reached 94.3%. It was observed a dependency between fluency and approved percentage points, whereas for the same fluency, 100% of the points have been approved in all phantoms. The approval criteria for IMRT plans recommended in most centers is 3% / 3mm with at least 95% of points approved, it can be concluded that, under these conditions, the IMRT plans with heterogeneity correction can be performed , however the quality control must be careful because the difficulty of the system to accurately predict the dose distribution in certain situations. (author)

  10. Surface/Surface Intersection Using Simulated Annealing Genetic Algorithm

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The genetic algorithm and marching method are integrated into a novel algorithm to solve the surface intersection problem. By combining genetic algorithm with local searching method the efficiency of evolution is greatly improved. By fully utilizing the global searching ability and instinct attribute for parallel computation of genetic algorithm and the local rapid convergency of marching method, the algorithm can compute the intersection robustly and generate correct topology of intersection curves. The details of the new algorithm are discussed here.

  11. A Recovery Algorithm for Self-Stabilizing Communication Protcocols

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    This paper presents a recovery algorithm for self-stabilizing communication protocols.It first describes some concepts and a formal description method for the algorithm.Then it proposes the algorithm procedures,proves its correctness and analyses its complexity.Finally,it also verifies the availability and efficiency of the algorithm by illustrating an example protocol with muiti-proceeses.

  12. Hologram production and representation for corrected image

    Science.gov (United States)

    Jiao, Gui Chao; Zhang, Rui; Su, Xue Mei

    2015-12-01

    In this paper, a CCD sensor device is used to record the distorted homemade grid images which are taken by a wide angle camera. The distorted images are corrected by using methods of position calibration and correction of gray with vc++ 6.0 and opencv software. Holography graphes for the corrected pictures are produced. The clearly reproduced images are obtained where Fresnel algorithm is used in graph processing by reducing the object and reference light from Fresnel diffraction to delete zero-order part of the reproduced images. The investigation is useful in optical information processing and image encryption transmission.

  13. Automatic Time Skew Detection and Correction

    OpenAIRE

    Korchagin, Danil

    2011-01-01

    In this paper, we propose a new approach for the automatic time skew detection and correction for multisource audiovisual data, recorded by different cameras/recorders during the same event. All recorded data are successfully tested for potential time skew problem and corrected based on ASR-related features. The core of the algorithm is based on perceptual time-quefrency analysis with a precision of 10 ms. The results show correct time skew detection and elimination in 100% of cases for a rea...

  14. Nonlinear correction of PSD with genetic algorithm based on neural network%遗传算法和神经网络结合的PSD非线性校正

    Institute of Scientific and Technical Information of China (English)

    刘春; 马颖

    2015-01-01

    针对光电位置传感器( PSD)检测系统在大坝变形观测中所呈现的非线性问题,建立改进的遗传算法和LM-BP神经网络结合的模型,对PSD的非线性进行补偿?该方法先用遗传算法对LM-BP网络的权阈值进行优化后再用LM-BP网络逼近任意非线性函数的特点对实际位置数据与理想值进行拟合后并进行测试,经过多次任意产生的种群优化后选择较为优秀个体作为神经网络的和阈值,并对任意位置进行校正,仿真结果表明,该方法克服了LM-BP网络对初始权阈值的依赖和泛化能力弱的特点,多次实验平均误差都小于1%,其泛化能力优于标准的遗传算法和神经网络结合的模型。%The position sensitive detector ( PSD) detection system in the observation of dam deformation can present nonlinear problem, so an improved genetic algorithm based on LM-BP neural network model is established to com-pensate the nonlinearity of PSD.Firstly, this method optimized the weight and threshold of LM-BP network by ge-netic algorithm, and let the actual position data fitted with the ideal value with the characteristics of LM-BP network to approximate any nonlinear function.The more excellent individual was chosen as the neural network weight value and threshold value after a population of optimizations repeatly and randomly.Finally, arbitrary position was correc-ted.The simulation results show that this method overcomes the dependent of LM-BP network on initial weight threshold and no-strongly generalization ability.The average error is less than 1% through several experiment ob-servations.Also, the generalization ability is better than the standard genetic algorithm based on neural network.

  15. Antimutagenic potential of curcumin on chromosomal aberrations in Allium cepa

    Institute of Scientific and Technical Information of China (English)

    RAGUNATHAN Irulappan; PANNEERSELVAM Natarajan

    2007-01-01

    Turmeric has long been used as a spice and food colouring agent in Asia. In the present investigation, the antimutagenic potential of curcumin was evaluated in Allium cepa root meristem cells. So far there is no report on the biological properties of curcumin in plant test systems. The root tip cells were treated with sodium azide at 200 and 300 μg/ml for 3 h and curcumin was given at 5, 10 and 20 μg/ml for 16 h, prior to sodium azide treatment. The tips were squashed after colchicine treatment and the cells were analyzed for chromosome aberration and mitotic index. Curcumin induces chromosomal aberration in Allium cepa root tip cells in an insignificant manner, when compared with untreated control. Sodium azide alone induces chromosomal aberrations significantly with increasing concentrations. The total number of aberrations was significantly reduced in root tip cells pretreated with curcumin. The study reveals that curcumin has antimutagenic potential against sodium azide induced chromosomal aberrations in Allium cepa root meristem cells. In addition, it showed mild cytotoxicity by reducing the percentage of mitotic index in all curcumin treated groups, but the mechanism of action remains unknown. The antimutagenic potential of curcumin is effective at 5 μg/ml in Allium cepa root meristem cells.

  16. 允差范围内变化的房间空调器测试结果算法修正%Correcting Algorithm on Experimental Results of Room Air Conditioner Performance with Dry-bulb and Wet-bulb Temperatures Changing within Allowances

    Institute of Scientific and Technical Information of China (English)

    张忠斌; 杜垲; 黄虎; 张若楠

    2014-01-01

    提出一种求解干湿球温度在国家标准允差范围内变化的制冷量和能效比实测结果向名义工况值回归逼近的修正算法,并以制冷工况下的室内侧干湿球温度允差范围变化的房间空调器制冷量和能效比测试结果为实例进行算法修正。该算法基于制冷量和能效比实测结果,采用多元高次方程逼近求解两者的回归方程,并用贝塞尔公式验证其收敛性。运用层次分析法(Analytic hierarchy process,AHP)量化分析干湿球温度对制冷量和能效比的影响程度,进而得出在干湿球温度允差范围内制冷量和能效比的修正算法。该修正算法可对任意工况下制冷量和能效比的实测值进行修正,并以此为基础对房间空调器能效等级进行评判。修正算法能更加准确地评判房间空调器能效等级,可对现行房间空调器性能测试方法进行完善。%A correcting algorithm is provided to work out regression equations to process the experimental results of cooling capacity (CC) and energy efficiency ratio (EER) of room air conditioner(RAC) when dry-bulb and wet-bulb temperatures (D&WBTs) change in the allowances set in national standard in China. Thereby, values of CC and EER under nominal working condition can be worked out. A case of the correcting algorithm is illustrated based on the experimental results of CC and EER with indoor D&WBTs changing in the allowances under space cooling condition. Based on the experimental results, the multiple high order equation is adopted to solve the regression equations of CC and EER respectively. Bessel formula is adopted to verify the convergence. The analytic hierarchy process (AHP) is adopted to present a quantitative analysis of the D&WBTs’ influence on CC and EER;thereby, the correcting equations for CC and EER with D&WBTs changing within the allowances are obtained. Within the allowances set in the national standard, these two correcting equations

  17. Spherical aberration and other higher-order aberrations in the human eye : from summary wave-front analysis data to optical variables relevant to visual perception

    NARCIS (Netherlands)

    Jansonius, Nomdo M.

    2010-01-01

    Wave-front analysis data from the human eye are commonly presented using the aberration coefficient c(4)(0) (primary spherical aberration) together with an overall measure of all higher-order aberrations. If groups of subjects are compared, however, the relevance of an observed difference cannot eas

  18. 基于改进多中心校正解耦内点法的动态最优潮流并行算法%Parallel Algorithm of Dynamic Optimal Power Flow Based on Improved Multiple Centrality Corrections Decoupling Interior Point Method

    Institute of Scientific and Technical Information of China (English)

    简金宝; 杨林峰; 全然

    2012-01-01

    This paper presents a new parallel algorithm to solve dynamic optimal power flow (DOPF) based on the methods of improved multiple centrality corrections (MCC) and decoupling. A parallel decoupling-factorization-substitution method for the correction equation of DOPF is proposed by integrating interior point method (IPM) framework and the block arrow correction equation, and then, the methods of dynamic increasing step length and adaptive corrections are given. A longer iteration step length and a better central point, which can be obtained by the proposed algorithm, give on the reduction in the number of iterations and savings in computing time than IPM. Most of operations in proposed method can be processed in parallel with decoupling. The sequential simulation results for systems that range in size from 6 to 118 buses show that the proposed method is fast and robust, and the simulations in multi-core cluster show that the method is very promising for large scale DOPF problems due to its excellent speed up and scalability.%基于改进的多中心校正(MCC)和解耦技术,提出一种求解动态最优潮流(DOPF)的并行算法。结合内点算法(IPM)框架与DOPF修正方程的分块箭形结构,给出修正方程的并行解耦-分解-回代解法。并结合这一解法特点,提出动态步长拉大技术及自适应最大校正次数技术,以单次迭代计算量小幅增加为代价,换取迭代步长的增大,迭代点中心性的提高,总迭代次数和计算时间的显著减少。解耦技术的使用,使得所提算法的核心计算都可并行完成。6~118节点系统的串行仿真结果表明,算法具有很好的鲁棒性和收敛速度,在多核集群系统上的并行仿真表明,算法具有理想的加速比和可扩放性,适合求解大规模的DOPF问题。

  19. Radiation-induced chromosome aberrations in human lymphocytes

    International Nuclear Information System (INIS)

    Dose-response relationships for unstable chromosome exchange aberrations were obtained after irradiation with 200 kV X-rays and 60Co gamma rays, the doses ranging within 0.05-3.0 Gy. The data points were fitted to the linear quadratic model Y = C + αD + βD2, and after the chromosome hits leading to two-break unstable aberrations were estimated, to the model average x = C +kD. The results fitted the latter model particularly well, the index of determination being 0.988 for gamma rays and 0.997 for X-rays. The RBE of 200 kV X-rays as compared with 60Co gamma radiation was 1.6, when primary chromosome breaks leading to dicentric and centric ring aberrations were used as the biological endpoint. (author)

  20. Biological dosimetry: chromosomal aberration analysis for dose assessment

    International Nuclear Information System (INIS)

    In view of the growing importance of chromosomal aberration analysis as a biological dosimeter, the present report provides a concise summary of the scientific background of the subject and a comprehensive source of information at the technical level. After a review of the basic principles of radiation dosimetry and radiation biology basic information on the biology of lymphocytes, the structure of chromosomes and the classification of chromosomal aberrations are presented. This is followed by a presentation of techniques for collecting blood, storing, transporting, culturing, making chromosomal preparations and scaring of aberrations. The physical and statistical parameters involved in dose assessment are discussed and examples of actual dose assessments taken from the scientific literature are given

  1. Split-plot fractional designs: Is minimum aberration enough?

    DEFF Research Database (Denmark)

    Kulahci, Murat; Ramirez, Jose; Tobias, Randy

    2006-01-01

    Split-plot experiments are commonly used in industry for product and process improvement. Recent articles on designing split-plot experiments concentrate on minimum aberration as the design criterion. Minimum aberration has been criticized as a design criterion for completely randomized fractional...... factorial design and alternative criteria, such as the maximum number of clear two-factor interactions, are suggested (Wu and Hamada (2000)). The need for alternatives to minimum aberration is even more acute for split-plot designs. In a standard split-plot design, there are several types of two...... for completely randomized designs. Consequently, we provide a modified version of the maximum number of clear two-factor interactions design criterion to be used for split-plot designs....

  2. Non-Gaussianity and CMB aberration and Doppler

    CERN Document Server

    Catena, Riccardo; Notari, Alessio; Renzi, Alessandro

    2013-01-01

    The peculiar motion of an observer with respect to the CMB rest frame induces a deflection in the arrival direction of the observed photons (also known as CMB aberration) and a Doppler shift in the measured photon frequencies. As a consequence, aberration and Doppler effects induce non trivial correlations between the harmonic coefficients of the observed CMB temperature maps. In this paper we investigate whether these correlations generate a bias on Non-Gaussianity estimators $f_{NL}$. We perform this analysis simulating a large number of temperature maps with Planck-like resolution (lmax $= 2000$) as different realizations of the same cosmological fiducial model (WMAP7yr). We then add to these maps aberration and Doppler effects employing a modified version of the HEALPix code. We finally evaluate a generalization of the Komatsu, Spergel and Wandelt Non-Gaussianity estimator for all the simulated maps, both when peculiar velocity effects have been considered and when these phenomena have been neglected. Usi...

  3. Global Intensity Correction in Dynamic Scenes

    NARCIS (Netherlands)

    Withagen, P.J.; Schutte, K.; Groen, F.C.A.

    2010-01-01

    Changing image intensities causes problems for many computer vision applications operating in unconstrained environments. We propose generally applicable algorithms to correct for global differences in intensity between images recorded with a static or slowly moving camera, regardless of the cause o

  4. Precise Wavefront Correction with an Unbalanced Nulling Interferometer for Exo-Planet Imaging Coronagraphs

    CERN Document Server

    Nishikawa, J; Murakami, N; Kotani, T

    2008-01-01

    Very high dynamical range coronagraphs targeting direct exo-planet detection (10^9 - 10^10 contrast) at small angular separation (few lambda/D units) usually require an input wavefront quality on the order of ten thousandths of wavelength RMS. We propose a novel method based on a pre-optics setup that behaves partly as a low-efficiency coronagraph, and partly as a high-sensitivity wavefront aberration compensator (phase and amplitude). The combination of the two effects results in a highly accurate corrected wavefront. First, an (intensity-) unbalanced nulling interferometer (UNI) performs a rejection of part of the wavefront electric field. Then the recombined output wavefront has its input aberrations magnified. Because of the unbalanced recombination scheme, aberrations can be free of phase singular points (zeros) and can therefore be compensated by a downstream phase and amplitude correction (PAC) adaptive optics system, using two deformable mirrors. In the image plane, the central star's peak intensity a...

  5. 一种天波超视距雷达电离层相位污染的校正算法%A Correction Algorithm for Ionospheric Phase Contamination in Sky-Wave Over-the-Horizon Radar

    Institute of Scientific and Technical Information of China (English)

    于文启; 陈建文; 杨春山

    2015-01-01

    The significant Doppler spread of over-the-horizon radar(OTHR)echoes induced by the time-variant phase modulation of ionosphere limits the detection performance for low-speed targets,such as ships. Considering the spreading and overlapping Bragg peaks caused by ionospheric phase contamination with large amplitude in long coherent integration time(CIT),a joint correction scheme based on wavelet transform and the method of hypothetical model is proposed in this paper.In the scheme,wavelet transform is firstly used to compensate the echo phase so that the positive and negative Bragg peaks can be roughly distinguished. Then an adaptive sliding window filter based on power ratio is applied to extract the calibration signal,and accurate phase contamination correction is carried out based on the hypothetical model in time domain.The simulation results show that the scheme is effective for the situation of the two Bragg peaks overlapping caused by ionospheric phase contamination with large amplitude,and has a better performance than the im-proved maximum entropy spectrum analysis (MESA)method.%时变电离层的相位污染使天波超视距雷达高频回波谱展宽,影响对舰船等低速目标的检测。针对长相干积累时回波谱受到电离层大幅度相位调制导致正负 Bragg 峰重叠的情况,提出一种联合小波变换和基于模型假设的校正方法(即 WTM 法)。该方法首先利用小波变换补偿回波相位,使得正负 Bragg 峰可以初步区分,然后利用基于功率比的自适应滑窗信号提取方法取出初步校正后的标校信号,最后在时域根据假设的模型对回波信号进行精确的相位污染校正。仿真结果表明,该方法对于电离层大幅度相位污染导致的高频回波谱正负 Bragg 峰重叠的情况具有明显的去污染效果,性能优于改进的 MESA 法。

  6. Algorithm for rendering physically correct soft shadows based on ambient occlusion masks%基于环境遮挡掩码的物理正确柔和阴影绘制算法

    Institute of Scientific and Technical Information of China (English)

    陈纯毅; 杨华民; 李文辉; 蒋振刚

    2012-01-01

    针对物理正确的柔和阴影绘制问题,提出一种使用环境遮挡掩码来实现面光源可见性计算的方法。在绘制前,预先创建一个环境遮挡掩码立方图。在绘制过程中,利用环境遮挡掩码立方图来计算所有与可见性测试四棱锥相交的三角形面片的环境遮挡掩码,并对它们作“与”运算,再通过遮挡距离测试操作即可求出哪些光源采样光线不受遮挡。与蒙特卡洛积分光照计算方法相比,本文方法不但能绘制出物理正确的柔和阴影,而且避免了大量的阴影光线求交测试操作,提高了绘制方程的求解效率。%Focusing on the problem of rendering physically correct soft shadows, a method is proposed which uses occlusion masks to evaluate the visibility of an area light source. Prior to the rendering process, a cube map of ambient occlusion masks is computed. In the rendering process, the cube map is employed to compute the ambient occlusion masks of triangles intersecting with a rectangular pyramid, which is used as the bounding volume for light-source sample rays in the visibility testing. Then the "and" bitwise operations are carried out on these ambient occlusion masks. Finally, based on the results of the bitwise operations, the blocking-distance testing is further utilized to determine which light-source sample rays are not blocked. Compared with the lighting computation method via Monte Carlo integration, the proposed method can not only render physically correct soft shadows, but also avoid a large number of intersection-testing operations for shadow rays. This advantage can enhance the efficiency in solving the rendering equation.

  7. A study on optical aberrations in parabolic neutron guides

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yu; Wang, Hongli; Liu, Yuntao [Neutron Scattering Laboratory, China Institute of Atomic Energy, Beijing 102413 (China); Zu, Yong [China International Engineering Consulting Corporation, Beijing 100048 (China); He, Linfeng; Wei, Guohai; Sun, Kai [Neutron Scattering Laboratory, China Institute of Atomic Energy, Beijing 102413 (China); Han, Songbai, E-mail: hansb@ciae.ac.cn [Neutron Scattering Laboratory, China Institute of Atomic Energy, Beijing 102413 (China); Chen, Dongfeng, E-mail: dongfeng@ciae.ac.cn [Neutron Scattering Laboratory, China Institute of Atomic Energy, Beijing 102413 (China)

    2015-06-21

    It is widely believed that a neutron beam can be focused to a small spot using a parabolic guide, which will significantly improve the flux. However, researchers have also noted challenges for the neutron inhomogeneous phase space distribution in parabolic focusing guide systems. In this paper, the sources of most prominent optical aberrations, such as an inhomogeneous phase space distribution and irregular divergence distribution, are discussed, and an optimization solution is also proposed. We indicate that optimizing the parabolic guide geometrical configuration removes almost all of the aberrations and yields a considerable intensity gain factor.

  8. Aberrations of the point spread function of a multimode fiber

    CERN Document Server

    Descloux, Adrien; Pinkse, Pepijn W H

    2016-01-01

    We investigate the point spread function of a multimode fiber. The distortion of the focal spot created on the fiber output facet is studied for a variety of the parameters. We develop a theoretical model of wavefront shaping through a multimode fiber and use it to confirm our experimental results and analyze the nature of the focal distortions. We show that aberration-free imaging with a large field of view can be achieved by using an appropriate number of segments on the spatial light modulator during the wavefront-shaping procedure. The results describe aberration limits for imaging with multimode fibers as in, e.g., microendoscopy.

  9. Investigation of spherical aberration effects on coherent lidar performance

    DEFF Research Database (Denmark)

    Hu, Qi; Rodrigo, Peter John; Iversen, Theis Faber Quist;

    2013-01-01

    different telescope configurations using a hard target. It is experimentally and numerically proven that the SA has a significant impact on lidar antenna efficiency and optimal beam truncation ratio. Furthermore, we demonstrate that both effective probing range and spatial resolution of the system are......In this paper we demonstrate experimentally the performance of a monostatic coherent lidar system under the influence of phase aberrations, especially the typically predominant spherical aberration (SA). The performance is evaluated by probing the spatial weighting function of the lidar system with...

  10. Chromosomal Aberrations in DNA Repair Defective Cell Lines: Comparisons of Dose Rate and Radiation Quality

    Science.gov (United States)

    George, K. A.; Hada, M.; Patel, Z.; Huff, J.; Pluth, J. M.; Cucinotta, F. A.

    2009-01-01

    Chromosome aberration yields were assessed in DNA double-strand break repair (DSB) deficient cells after acute doses of gamma-rays or high-LET iron nuclei, or low dose-rate (0.018 Gy/hr) gamma-rays. We studied several cell lines including fibroblasts deficient in ATM (product of the gene that is mutated in ataxia telangiectasia patients) or NBS (product of the gene mutated in the Nijmegen breakage syndrome), and gliomablastoma cells that are proficient or lacking in DNA-dependent protein kinase, DNA-PK activity. Chromosomes were analyzed using the fluorescence in-situ hybridization (FISH) chromosome painting method in cells at the first division post-irradiation and chromosome aberrations were identified as either simple exchanges (translocations and dicentrics) or complex exchanges (involving >2 breaks in 2 or more chromosomes). Gamma radiation induced higher yields of both simple and complex exchanges in the DSB repair defective cells than in the normal cells. The quadratic dose-response terms for both chromosome exchange types were significantly higher for the ATM and NBS defective lines than for normal fibroblasts. However, the linear dose-response term was significantly higher only for simple exchanges in the NBS cells. Large increases in the quadratic dose response terms indicate the important roles of ATM and NBS in chromatin modifications that facilitate correct DSB repair and minimize aberration formation. Differences in the response of AT and NBS deficient cells at lower doses suggests important questions about the applicability of observations of radiation sensitivity at high dose to low dose exposures. For all iron nuclei irradiated cells, regression models preferred purely linear and quadratic dose responses for simple and complex exchanges, respectively. All the DNA repair defective cell lines had lower Relative biological effectiveness (RBE) values than normal cells, the lowest being for the DNA-PK-deficient cells, which was near unity. To further

  11. Improved Adaptive IR Image Non-uniformity Correction Algorithm Based on Neural Network%基于神经网络的改进型红外图像自适应非均匀校正算法

    Institute of Scientific and Technical Information of China (English)

    聂瑞杰; 李丽娟; 王朝林

    2015-01-01

    针对传统的基于神经网络的自适应非均匀性校正(Neural-Network-based Non-Uniformity Correction,NN-NUC)算法在实际应用中存在校正能力有限和容易产生鬼影的问题,深入分析了NN-NUC算法中的鬼影产生过程,并给出了抑制鬼影的一般性方法;然后结合实际红外成像系统的特点,提出了一种改进型NN-NUC算法.仿真实验结果表明,该算法可以最大限度地抑制场景鬼影的产生,并可有效减小系统输出图像的非均匀性噪声.此外,本文算法计算量小,且易于用硬件实现,因此具有很好的工程应用价值.

  12. NWS Corrections to Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Form B-14 is the National Weather Service form entitled 'Notice of Corrections to Weather Records.' The forms are used to make corrections to observations on forms...

  13. Nuevo algoritmo de detección y corrección de píxeles anómalos en imágenes A new algorithm for detecting and correcting bad pixels in infrared images

    Directory of Open Access Journals (Sweden)

    Restrepo Gir��n Andrés David

    2010-08-01

    Full Text Available Se expone un nuevo algoritmo de procesamiento de imágenes para detectar y corregir píxeles anómalos que resalten de manera individual entre sus vecinos en imágenes de una secuencia térmica obtenida a partir de un procedimiento de termografía activa, sin afectar la apariencia global de cada imagen, como ocurre al emplear una estrategia clásica de filtrado espacial. Como resultado principal de este filtrado selectivo, se detectan y reemplazan en un alto porcentaje aquellos píxeles defectuosos de fabricación o por el uso continuo del dispositivo CCD de la cámara infrarroja, lo cual re- duce el riesgo de malas interpretaciones en el análisis posterior. Para el desarrollo y prueba del algoritmo propuesto se utilizaron secuencias de video tomadas con una cámara Cincinnati Electronics de indio-antimonio (InSb para inspeccionar láminas de CFRP (plástico reforzado con fibra de carbono mediante la técnica de termografía activa. Los resultados del algoritmo se comparan con una lista de píxeles defectuosos dada por el fabricante de la cámara, arrojando un porcentaje de coincidencia de alrededor del 70%. El presente trabajo toma relevancia al considerar que en la literatura científica se encuentran muy pocos estudios en este campo, centrándose la mayoría en el preprocesamiento de imágenes astronómicas; además, en Colombia se está en una etapa de introducción creciente de técnicas de evaluación no destructiva por termografía (ENDT en amplios sectores industriales que incluyen generación y transmisión de energía, in- genios azucareros y aeronáutica militar, entre otros.An image processing algorithm detects and replaces abnormal pixels individually, highlighting them amongst their neighbours in a sequence of thermal images without affecting overall texture, like classical filtering does. Bad pixels from manufacture or constant use of a CCD device in an IR camera are thus detected and replaced with a very good success rate

  14. Experimental verification of the minimum number of diffractive zones for effective chromatic correction in the LWIR

    Science.gov (United States)

    Ramsey, J. L.; Walsh, K. F.; Smith, M.; Deegan, J.

    2016-05-01

    With the move to smaller pixel sizes in the longwave IR region there has been a push for shorter focal length lenses that are smaller, cheaper and lighter and that resolve lower spatial frequencies. As a result lenses must have better correction for both chromatic and monochromatic aberrations. This leads to the increased use of aspheres and diffractive optical elements (kinoforms). With recent developments in the molding of chalcogenide materials these aspheres and kinoforms are more cost effective to manufacture. Without kinoforms the axial color can be on the order of 15 μm which degrades the performance of the lens at the Nyquist frequency. The kinoforms are now on smaller elements and are correcting chromatic aberration which is on the order of the design wavelength. This leads to kinoform structures that do not require large phase changes and therefore have 1.5 to just over 2 zones. The question becomes how many zones are required to correct small amounts of chromatic aberration in the system and are they functioning as predicted by the lens design software? We investigate both the design performance and the as-built performance of two designs that incorporate kinoforms for the correction of axial chromatic aberration.

  15. Effect of Coma Aberration on Orbital Angular Momentum Spectrum of Vortex Beams

    Institute of Scientific and Technical Information of China (English)

    CHEN Zi-Yang; PU Ji-Xiong

    2009-01-01

    Spiral spectra of vortex beams with coma aberration are studied.It is shown that the orbital angular momentum (OAM) states of vortex beams with coma aberration are different from those aberration-free vortex beams.Spiral spectra of beams with coma aberration are spreading.It is found that in the presence of coma aberration,the vortex beams contain not only the original OAM component but also other components.A larger coma aberration coefficient and/or a larger beam waist will lead to a wider spreading of the spiral spectrum. The results may have potential applications in information encoding and transmittance.

  16. Aberration of a negative ion beam caused by space charge effect

    International Nuclear Information System (INIS)

    Aberrations are inevitable when the charged particle beams are extracted, accelerated, transmitted, and focused with electrostatic and magnetic fields. In this study, we investigate the aberration of a negative ion accelerator for a neutral beam injector theoretically, especially the spherical aberration caused by the negative ion beam expansion due to the space charge effect. The negative ion current density profiles with the spherical aberration are compared with those without the spherical aberration. It is found that the negative ion current density profiles in a log scale are tailed due to the spherical aberration.

  17. Adaptive compensation of lower order thermal aberrations in concave-convex power oscillators under variable pump conditions

    Science.gov (United States)

    Jackel, Steven M.; Moshe, Inon

    2000-09-01

    A Nd:Cr:GSGG concave-convex power oscillator was developed that utilized both an adaptive mirror comprised of spherical and cylindrical optical elements together with a Faraday rotator to dynamically eliminate lower order aberrations (thermal focusing, astigmatism, and bipolar focusing). An adaptively controlled collimating lens corrected for shifts in the mode-waist position. The addition of a polarizer and a reentrant mirror totally eliminated thermal birefringence losses. The techniques developed are attractive in any solid state laser that must work under changing pump power conditions.

  18. Error Correction in Classroom

    Institute of Scientific and Technical Information of China (English)

    Dr. Grace Zhang

    2000-01-01

    Error correction is an important issue in foreign language acquisition. This paper investigates how students feel about the way in which error correction should take place in a Chinese-as-a foreign-language classroom, based on empirical data of a large scale. The study shows that there is a general consensus that error correction is necessary. In terms of correction strategy, the students preferred a combination of direct and indirect corrections, or a direct only correction. The former choice indicates that students would be happy to take either so long as the correction gets done.Most students didn't mind peer correcting provided it is conducted in a constructive way. More than halfofthe students would feel uncomfortable ifthe same error they make in class is corrected consecutively more than three times. Taking these findings into consideration, we may want to cncourage peer correcting, use a combination of correction strategies (direct only if suitable) and do it in a non-threatening and sensitive way. It is hoped that this study would contribute to the effectiveness of error correction in a Chinese language classroom and it may also have a wider implication on other languages.

  19. Algorithmic Adventures

    CERN Document Server

    Hromkovic, Juraj

    2009-01-01

    Explores the science of computing. This book starts with the development of computer science, algorithms and programming, and then explains and shows how to exploit the concepts of infinity, computability, computational complexity, nondeterminism and randomness.

  20. A Bayesian approach for energy-based estimation of acoustic aberrations in high intensity focused ultrasound treatment

    CERN Document Server

    Hosseini, Bamdad; Pichardo, Samuel; Constanciel, Elodie; Drake, James M; Stockie, John M

    2016-01-01

    High intensity focused ultrasound is a non-invasive method for treatment of diseased tissue that uses a beam of ultrasound in order to generate heat within a small volume. A common challenge in application of this technique is that heterogeneity of the biological medium can defocus the ultrasound beam. In this study, the problem of refocusing the beam is reduced to the Bayesian inverse problem of estimating the acoustic aberration due to the biological tissue from acoustic radiative force imaging data. The solution to this problem is a posterior probability density on the aberration which is sampled using a Metropolis-within-Gibbs algorithm. The framework is tested using both a synthetic and experimental dataset. This new approach has the ability to obtain a good estimate of the aberrations from a small dataset, as little as 32 sonication tests, which can lead to significant speedup in the treatment process. Furthermore, this framework is very flexible and can work with a wide range of sonication tests and so...

  1. High-Resolution Transmission Electron Microscopy Using Negative Spherical Aberration

    Science.gov (United States)

    Jia, Chun-Lin; Lentzen, Markus

    2004-04-01

    A novel imaging mode for high-resolution transmission electron microscopy is described. It is based on the adjustment of a negative value of the spherical aberration CS of the objective lens of a transmission electron microscope equipped with a multipole aberration corrector system. Negative spherical aberration applied together with an overfocus yields high-resolution images with bright-atom contrast. Compared to all kinds of images taken in conventional transmission electron microscopes, where the then unavoidable positive spherical aberration is combined with an underfocus, the contrast is dramatically increased. This effect can only be understood on the basis of a full nonlinear imaging theory. Calculations show that the nonlinear contrast contributions diminish the image contrast relative to the linear image for a positive-CS setting whereas they reinforce the image contrast relative to the linear image for a negative-CS setting. The application of the new mode to the imaging of oxygen in SrTiO3 and YBa2Cu3O7 demonstrates the benefit to materials science investigations. It allows us to image directly, without further image processing, strongly scattering heavy-atom columns together with weakly scattering light-atom columns.

  2. Polarization aberrations of radiation at the lens focus

    NARCIS (Netherlands)

    Sokolov, AL

    2005-01-01

    The polarization aberrations of radiation at the lens focus are calculated with allowance for diffraction effects. Calculations are performed using the representation of radiation as a coherent set of Hermite-Gauss modes with certain amplitudes, phases, and polarizations. An expression for the longi

  3. Consequences of Aberrant Hedgehog Signaling During Zebrafish Development

    NARCIS (Netherlands)

    Koudijs, M.J.

    2007-01-01

    The Hedgehog signaling pathway is controlling proliferation, patterning and differentiation during development of vertebrates and invertebrates. Aberrant Hedgehog activity has been shown to be one of the underlying causes of a number of congenital disorders and multiple types of cancer. We investiga

  4. The Aberrant Salience Inventory: A New Measure of Psychosis Proneness

    Science.gov (United States)

    Cicero, David C.; Kerns, John G.; McCarthy, Denis M.

    2010-01-01

    Aberrant salience is the unusual or incorrect assignment of salience, significance, or importance to otherwise innocuous stimuli and has been hypothesized to be important for psychosis and psychotic disorders such as schizophrenia. Despite the importance of this concept in psychosis research, no questionnaire measures are available to assess…

  5. Chromosome aberrations induced in human lymphocytes by neutron irradiation

    International Nuclear Information System (INIS)

    In vitro dose-response curves of unstable chromosome aberrations in human lymphocytes have been obtained for neutron spectra of mean energies 0.7, 0.9, 7.6 and 14.7 MeV. The aberration yields have been fitted to the quadratic function Y = αD + βD2, which is consistent with the single-track and two-track model of aberration formation. However with high-LET radiation, the linear component of yield, corresponding to damage caused by single tracks, predominates, and this term becomes more dominant with increasing LET, so that for fission spectrum neutrons the relationship is linear, Y = αD. At low doses, such as those received by radiation workers, limiting r.b.e. values between 13 and 47 were obtained relative to 60Co γ-radiation. At higher doses, as used in radiotherapy, the values were much lower; ranging from 2.7 to 8 at 200 rad of equivalent γ-radiation. Both sets of r.b.e. values correlated well with track-averaged LET but not with dose-averaged LET. When the numbers of cells without aberrations were plotted against radiation dose, curves were obtained which are similar in shape to those for conventional cell-survival experiments with comparable neutron spectra. The D0 values obtained in the present study are close to those from other cell systems. (author)

  6. Frequency of primary amenorrhea due to chromosomal aberration

    International Nuclear Information System (INIS)

    Objective: To find out the frequency of primary amenorrhea due to chromosomal aberration and the different options available for management. Subjects and Methods: All patients with primary amenorrhea due to chromosomal aberrations were included in study. Patient's detailed history, general physical examination, presence or absence of secondary sexual characteristics, abdominal and pelvic examination finding were noted. Targeted investigations, including ultrasound, hormonal assay, buccal smear and karyotyping results were recorded. The management options were individually tailored with focus n psychological management. Results: Eighteen patients out of 30,000 patients were diagnosed as having primary amenorrhea. Six had primary amenorrhea due to chromosomal aberrations with the frequency of 0.02%. The age at presentation was 20 years and above in 50%. The most common cause was Turner's syndrome seen in 4 out of 6. The presenting symptoms were delay in onset of menstruation in 05 patients and primary infertility in 01 patient. Conclusion: Primary amenorrhea due to chromosomal aberration is an uncommon condition requiring an early and accurate diagnosis. Turner's syndrome is a relatively common cause of this condition. Management should be multi-disciplinary and individualized according to the patient's age and symptom at presentation. Psychological management is very important and counselling throughout treatment is recommended. (author)

  7. Analysis of Chromosomal Aberrations after Low and High Dose Rate Gamma Irradiation in ATM or NBS Suppressed Human Fibroblast Cells

    Science.gov (United States)

    Hada, M.; Huff, J. L.; Patel, Z.; Pluth, J. M.; George, K. A.; Cucinotta, F. A.

    2009-01-01

    A detailed understanding of the biological effects of heavy nuclei is needed for space radiation protection and for cancer therapy. High-LET radiation produces more complex DNA lesions that may be non-repairable or that may require additional processing steps compared to endogenous DSBs, increasing the possibility of misrepair. Interplay between radiation sensitivity, dose, and radiation quality has not been studied extensively. Previously we studied chromosome aberrations induced by low- and high- LET radiation in several cell lines deficient in ATM (ataxia telangactasia mutated; product of the gene that is mutated in ataxia telangiectasia patients) or NBS (nibrin; product of the gene mutated in the Nijmegen breakage syndrome), and gliomablastoma cells that are proficient or lacking in DNA-dependent protein kinase (DNA-PK) activity. We found that the yields of both simple and complex chromosomal aberrations were significantly increased in the DSB repair defective cells compared to normal cells. The increased aberrations observed for the ATM and NBS defective lines was due to a significantly larger quadratic dose-response term compared to normal fibroblasts for both simple and complex aberrations, while the linear dose-response term was significantly higher in NBS cells only for simple exchanges. These results point to the importance of the functions of ATM and NBS in chromatin modifications that function to facilitate correct DSB repair and minimize aberration formation. To further understand the sensitivity differences that were observed in ATM and NBS deficient cells, in this study, chromosomal aberration analysis was performed in normal lung fibroblast cells treated with KU-55933, a specific ATM kinase inhibitor, or Mirin, an MRN complex inhibitor involved in activation of ATM. We are also testing siRNA knockdown of these proteins. Normal and ATM or NBS suppressed cells were irradiated with gamma-rays and chromosomes were collected with a premature chromosome

  8. Chromatin structure and ionizing-radiation-induced chromosome aberrations

    International Nuclear Information System (INIS)

    The possible influence of chromatic structure or activity on chromosomal radiosensitivity was studied. A cell line was isolated which contained some 105 copies of an amplified plasmid in a single large mosquito artificial chromosome (MAC). This chromosome was hypersensitive to DNase I. Its radiosensitivity was some three fold greater than normal mosquito chromosomes in the same cell. In cultured human cells irradiated during G0, the initial breakage frequency in chromosome 4, 19 and the euchromatic and heterochromatic portions of the Y chromosome were measured over a wide range of doses by inducing Premature Chromosome Condensation (PCC) immediately after irradiation with Cs-137 gamma rays. No evidence was seen that Y heterochromatin or large fragments of it remained unbroken. The only significant deviation from the expected initial breakage frequency per Gy per unit length of chromosome was that observed for the euchromatic portion of the Y chromosome, with breakage nearly twice that expected. The development of aberrations involving X and Y chromosomes at the first mitosis after irradation was also studied. Normal female cells sustained about twice the frequency of aberrations involving X chromosomes for a dose of 7.3 Gy than the corresponding male cells. Fibroblasts from individuals with supernumerary X chromosomes did not show any further increase in X aberrations for this dos. The frequency of aberrations involving the heterochromatic portion of the long arm of the Y chromosome was about what would be expected for a similar length of autosome, but the euchromatic portion of the Y was about 3 times more radiosensitive per unit length. 5-Azacytidine treatment of cultured human female fibroblasts or fibroblasts from a 49,XXXXY individual, reduced the methylation of cytosine residues in DNA, and resulted in an increased chromosomal radiosensitivity in general, but it did not increase the frequency of aberrations involving the X chromosomes

  9. Correction of a Depth-Dependent Lateral Distortion in 3D Super-Resolution Imaging.

    Directory of Open Access Journals (Sweden)

    Lina Carlini

    Full Text Available Three-dimensional (3D localization-based super-resolution microscopy (SR requires correction of aberrations to accurately represent 3D structure. Here we show how a depth-dependent lateral shift in the apparent position of a fluorescent point source, which we term `wobble`, results in warped 3D SR images and provide a software tool to correct this distortion. This system-specific, lateral shift is typically > 80 nm across an axial range of ~ 1 μm. A theoretical analysis based on phase retrieval data from our microscope suggests that the wobble is caused by non-rotationally symmetric phase and amplitude aberrations in the microscope's pupil function. We then apply our correction to the bacterial cytoskeletal protein FtsZ in live bacteria and demonstrate that the corrected data more accurately represent the true shape of this vertically-oriented ring-like structure. We also include this correction method in a registration procedure for dual-color, 3D SR data and show that it improves target registration error (TRE at the axial limits over an imaging depth of 1 μm, yielding TRE values of < 20 nm. This work highlights the importance of correcting aberrations in 3D SR to achieve high fidelity between the measurements and the sample.

  10. Biological terrorism preparedness evaluating the performance of the Early Aberration Reporting System (EARS) syndromic surveillance algorithms

    OpenAIRE

    Hegler, Benjamin L.

    2007-01-01

    After the terrorist attacks of September 11, 2001, questions developed over how quickly the country could respond if a bioterrorism attack was to occur. "Syndromic surveillance" systems are a relatively new concept that is being implemented and used by public health practitioners to attempt to detect a bioterrorism attack earlier than would be possible using conventional biosurveillance methods. The idea behind using syndromic surveillance is to detect a bioterrorist attack by monitoring ...

  11. An Incremental Approach to Automatic Algorithm Design

    Institute of Scientific and Technical Information of China (English)

    LUAN Shangmin; LI Wei

    1999-01-01

    This paper presents an incrementalapproach to automatic algorithm design, which can be described byalgebraic specifications precisely and conveniently. The definitions ofselection operator and extension operator which can be defined bystrategy relations and transformations are given in order to model theprocess of finding the solution of a problem. Also discussed is itsobject-oriented implementation. The functional specification and thedesign specification for an algorithm are given in one framework so thatthe correctness of the algorithm can be easily proved.

  12. Subjective face recognition difficulties, aberrant sensibility, sleeping disturbances and aberrant eating habits in families with Asperger syndrome

    Directory of Open Access Journals (Sweden)

    Källman Tiia

    2005-04-01

    Full Text Available Abstract Background The present study was undertaken in order to determine whether a set of clinical features, which are not included in the DSM-IV or ICD-10 for Asperger Syndrome (AS, are associated with AS in particular or whether they are merely a familial trait that is not related to the diagnosis. Methods Ten large families, a total of 138 persons, of whom 58 individuals fulfilled the diagnostic criteria for AS and another 56 did not to fulfill these criteria, were studied using a structured interview focusing on the possible presence of face recognition difficulties, aberrant sensibility and eating habits and sleeping disturbances. Results The prevalence for face recognition difficulties was 46.6% in individuals with AS compared with 10.7% in the control group. The corresponding figures for subjectively reported presence of aberrant sensibilities were 91.4% and 46.6%, for sleeping disturbances 48.3% and 23.2% and for aberrant eating habits 60.3% and 14.3%, respectively. Conclusion An aberrant processing of sensory information appears to be a common feature in AS. The impact of these and other clinical features that are not incorporated in the ICD-10 and DSM-IV on our understanding of AS may hitherto have been underestimated. These associated clinical traits may well be reflected by the behavioural characteristics of these individuals.

  13. Automatic Contextual Text Correction Using The Linguistic Habits Graph Lhg

    Directory of Open Access Journals (Sweden)

    Marcin Gadamer

    2009-01-01

    Full Text Available Automatic text correction is an essential problem of today text processors and editors. Thispaper introduces a novel algorithm for automation of contextual text correction using a LinguisticHabit Graph (LHG also introduced in this paper. A specialist internet crawler hasbeen constructed for searching through web sites in order to build a Linguistic Habit Graphafter text corpuses gathered in polish web sites. The achieved correction results on a basis ofthis algorithm using this LHG were compared with commercial programs which also enableto make text correction: Microsoft Word 2007, Open Office Writer 3.0 and search engineGoogle. The achieved results of text correction were much better than correction made bythese commercial tools.

  14. Geometric Correction for Braille Document Images

    Directory of Open Access Journals (Sweden)

    Padmavathi.S

    2016-04-01

    Full Text Available Braille system has been used by the visually impair ed people for reading.The shortage of Braille books has caused a need for conversion of Braille t o text. This paper addresses the geometric correction of a Braille document images. Due to the standard measurement of the Braille cells, identification of Braille characters could be achie ved by simple cell overlapping procedure. The standard measurement varies in a scaled document an d fitting of the cells become difficult if the document is tilted. This paper proposes a line fitt ing algorithm for identifying the tilt (skew angle. The horizontal and vertical scale factor is identified based on the ratio of distance between characters to the distance between dots. Th ese are used in geometric transformation matrix for correction. Rotation correction is done prior to scale correction. This process aids in increased accuracy. The results for various Braille documents are tabulated.

  15. Numerical and structural chromosome aberrations in cauliflower (Brassica oleracea var. botrytis) and Arabidopsis thaliana

    NARCIS (Netherlands)

    Ji, X.

    2014-01-01

    Numerical and structural chromosome aberrations in cauliflower (Brassica oleracea var. botrytis) and Arabidopsis thaliana. I studied numerical and structural chromosome aberrations in cauliflower (Brassica oleracea var. botrytis) and Arabidopsis thaliana. The large genomic changes are important for

  16. Aberrations measurement of freeform spectacle lenses based on Hartmann wavefront technology.

    Science.gov (United States)

    Yu, Jing; Fang, Fengzhou; Qiu, Zhongjun

    2015-02-10

    Freeform spectacle lenses have been popularized in the past few years. Traditional evaluation methods only focused on the refractive power parameters. The inspection technology of wavefront aberration has been introduced to optometry. In this paper, the wavefront aberration is used to evaluate the freeform spectacle lenses. The Shack-Hartmann wavefront technology is used to measure the same zones on the lenses with different designed forms. It shows that the aberration distributions are different from each other. The design with the freeform surface on the back can obtain the smallest aberrations in the entire surface. The aberrations on different zones for the same lens are analyzed. The blending zones show the greatest aberrations. The aberration on the progressive corridor is greater than the other zones. The Hartmann wavefront technology can be used to measure the wavefront aberration of freeform spectacle lenses. PMID:25968012

  17. Off-Angle Iris Correction Methods

    Energy Technology Data Exchange (ETDEWEB)

    Santos-Villalobos, Hector J [ORNL; Thompson, Joseph T [ORNL; Karakaya, Mahmut [ORNL; Boehnen, Chris Bensing [ORNL

    2016-01-01

    In many real world iris recognition systems obtaining consistent frontal images is problematic do to inexperienced or uncooperative users, untrained operators, or distracting environments. As a result many collected images are unusable by modern iris matchers. In this chapter we present four methods for correcting off-angle iris images to appear frontal which makes them compatible with existing iris matchers. The methods include an affine correction, a retraced model of the human eye, measured displacements, and a genetic algorithm optimized correction. The affine correction represents a simple way to create an iris image that appears frontal but it does not account for refractive distortions of the cornea. The other method account for refraction. The retraced model simulates the optical properties of the cornea. The other two methods are data driven. The first uses optical flow to measure the displacements of the iris texture when compared to frontal images of the same subject. The second uses a genetic algorithm to learn a mapping that optimizes the Hamming Distance scores between off-angle and frontal images. In this paper we hypothesize that the biological model presented in our earlier work does not adequately account for all variations in eye anatomy and therefore the two data-driven approaches should yield better performance. Results are presented using the commercial VeriEye matcher that show that the genetic algorithm method clearly improves over prior work and makes iris recognition possible up to 50 degrees off-angle.

  18. Environmental transmission electron microscopy for catalyst materials using a spherical aberration corrector

    International Nuclear Information System (INIS)

    Atomic resolution has been obtained using environmental transmission electron microscopy (ETEM) by installing a spherical aberration corrector (Cs-corrector) on the objective lens. Simultaneously, the technology for controlling the environment around a specimen in ETEM has advanced significantly in the past decade. Quantification methodology has recently been established for deriving relevant experimental data in catalyst materials from substantial and systematic ETEM observation at the atomic scale. With this background, this paper summarizes aspects of the evolutional microscopy technique: necessary conditions for atomic resolution in ETEM; reduction of the scattering of electrons by the medium surrounding a specimen; and an environmental cell for structural imaging of a crystalline specimen. The high spatial resolution of a Cs-corrected ETEM is demonstrated for different observation conditions. After statistical analysis combined with numerical image analysis of ETEM data is briefly described, the recent applications of the Cs-corrected ETEM to catalyst materials are reviewed. For gold nanoparticulate catalysts, the structural information on the reaction sites and adsorption sites are deduced. For Pt nanoparticulate catalysts, ETEM studies elucidate the correlation between the catalytic activity and the morphology of the nanoparticles. These studies also reveal oxidation and reduction on the topmost Pt surface layer at the atomic scale. Finally, current issues and the future perspectives of Cs-corrected ETEM are summarized, including the reproducibility of ETEM observation data, the control of environments, the critical evaluation of electron irradiation effects, the full implementation of transmission electron microscopy technology in ETEM, and the safety issues for an ETEM laboratory. - Highlights: • Advancement of Cs corrected environmental transmission electron microscopy. • Structural determination of catalyst materials in reaction environments.

  19. Environmental transmission electron microscopy for catalyst materials using a spherical aberration corrector

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, Seiji, E-mail: takeda@sanken.osaka-u.ac.jp; Kuwauchi, Yasufumi; Yoshida, Hideto

    2015-04-15

    Atomic resolution has been obtained using environmental transmission electron microscopy (ETEM) by installing a spherical aberration corrector (Cs-corrector) on the objective lens. Simultaneously, the technology for controlling the environment around a specimen in ETEM has advanced significantly in the past decade. Quantification methodology has recently been established for deriving relevant experimental data in catalyst materials from substantial and systematic ETEM observation at the atomic scale. With this background, this paper summarizes aspects of the evolutional microscopy technique: necessary conditions for atomic resolution in ETEM; reduction of the scattering of electrons by the medium surrounding a specimen; and an environmental cell for structural imaging of a crystalline specimen. The high spatial resolution of a Cs-corrected ETEM is demonstrated for different observation conditions. After statistical analysis combined with numerical image analysis of ETEM data is briefly described, the recent applications of the Cs-corrected ETEM to catalyst materials are reviewed. For gold nanoparticulate catalysts, the structural information on the reaction sites and adsorption sites are deduced. For Pt nanoparticulate catalysts, ETEM studies elucidate the correlation between the catalytic activity and the morphology of the nanoparticles. These studies also reveal oxidation and reduction on the topmost Pt surface layer at the atomic scale. Finally, current issues and the future perspectives of Cs-corrected ETEM are summarized, including the reproducibility of ETEM observation data, the control of environments, the critical evaluation of electron irradiation effects, the full implementation of transmission electron microscopy technology in ETEM, and the safety issues for an ETEM laboratory. - Highlights: • Advancement of Cs corrected environmental transmission electron microscopy. • Structural determination of catalyst materials in reaction environments.

  20. A Class of Coning Algorithms Based on a Half-Compressed Structure

    Directory of Open Access Journals (Sweden)

    Chuanye Tang

    2014-08-01

    Full Text Available Aiming to advance the coning algorithm performance of strapdown inertial navigation systems, a new half-compressed coning correction structure is presented. The half-compressed algorithm structure is analytically proven to be equivalent to the traditional compressed structure under coning environments. The half-compressed algorithm coefficients allow direct configuration from traditional compressed algorithm coefficients. A type of algorithm error model is defined for coning algorithm performance evaluation under maneuver environment conditions. Like previous uncompressed algorithms, the half-compressed algorithm has improved maneuver accuracy and retained coning accuracy compared with its corresponding compressed algorithm. Compared with prior uncompressed algorithms, the formula for the new algorithm coefficients is simpler.

  1. A Case Study of the Reduction of Aberrant, Repetitive Responses of an Adolescent with Autism.

    Science.gov (United States)

    Gunter, Philip L.; And Others

    1993-01-01

    In this case study, music was applied noncontingently and contingently across four settings with an adolescent male with autism, to reduce aberrant, repetitive vocalizations. The intervention was associated with dramatic reductions in the primary aberrant behavior and reductions in two other aberrant behaviors. Task performance was differentially…

  2. Algorithmic Self

    DEFF Research Database (Denmark)

    Markham, Annette

    This paper takes an actor network theory approach to explore some of the ways that algorithms co-construct identity and relational meaning in contemporary use of social media. Based on intensive interviews with participants as well as activity logging and data tracking, the author presents a richly...... layered set of accounts to help build our understanding of how individuals relate to their devices, search systems, and social network sites. This work extends critical analyses of the power of algorithms in implicating the social self by offering narrative accounts from multiple perspectives. It also...

  3. Combinatorial algorithms

    CERN Document Server

    Hu, T C

    2002-01-01

    Newly enlarged, updated second edition of a valuable text presents algorithms for shortest paths, maximum flows, dynamic programming and backtracking. Also discusses binary trees, heuristic and near optimums, matrix multiplication, and NP-complete problems. 153 black-and-white illus. 23 tables.Newly enlarged, updated second edition of a valuable, widely used text presents algorithms for shortest paths, maximum flows, dynamic programming and backtracking. Also discussed are binary trees, heuristic and near optimums, matrix multiplication, and NP-complete problems. New to this edition: Chapter 9

  4. Self-Correcting HVAC Controls Project Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, Nicholas; Brambley, Michael R.; Katipamula, Srinivas; Cho, Heejin; Goddard, James K.; Dinh, Liem H.

    2010-01-04

    This document represents the final project report for the Self-Correcting Heating, Ventilating and Air-Conditioning (HVAC) Controls Project jointly funded by Bonneville Power Administration (BPA) and the U.S. Department of Energy (DOE) Building Technologies Program (BTP). The project, initiated in October 2008, focused on exploratory initial development of self-correcting controls for selected HVAC components in air handlers. This report, along with the companion report documenting the algorithms developed, Self-Correcting HVAC Controls: Algorithms for Sensors and Dampers in Air-Handling Units (Fernandez et al. 2009), document the work performed and results of this project.

  5. Geometric correction of deformed chromosomes for automatic Karyotyping.

    Science.gov (United States)

    Khan, Shadab; DSouza, Alisha; Sanches, João; Ventura, Rodrigo

    2012-01-01

    Automatic Karyotyping is the process of classifying chromosomes from an unordered karyogram into their respective classes to create an ordered karyogram. Automatic karyotyping algorithms typically perform geometrical correction of deformed chromosomes for feature extraction; these features are used by classifier algorithms for classifying the chromosomes. Karyograms of bone marrow cells are known to have poor image quality. An example of such karyograms is the Lisbon-K(1) (LK(1)) dataset that is used in our work. Thus, to correct the geometrical deformation of chromosomes from LK(1), a robust method to obtain the medial axis of the chromosome was necessary. To address this problem, we developed an algorithm that uses the seed points to make a primary prediction. Subsequently, the algorithm computes the distance of boundary from the predicted point, and the gradients at algorithm-specified points on the boundary to compute two auxiliary predictions. Primary prediction is then corrected using auxiliary predictions, and a final prediction is obtained to be included in the seed region. A medial axis is obtained this way, which is further used for geometrical correction of the chromosomes. This algorithm was found capable of correcting geometrical deformations in even highly distorted chromosomes with forked ends.

  6. Studies on chromosome aberrations in workers occupationally exposed to radiation

    International Nuclear Information System (INIS)

    Cytogenetic assays for unstable chromosomes were performed on 54 medical radiation workers who are occupationally exposed to radiation and 42 controls. A total of 15,577 metaphase cells were scored. The frequencies of dicentrics and acentric chromosomes on controls were 0.52*10-3 and 0.82*10-2, respectively. On radiation workers those were 2.28*10-3 and 1.34*10-2, respectively. Though the frequencies of all types of chromosome aberrations in the workers were higher than those in the controls, the only significant difference was found in the case of dicentrics (P 0.05) except exposure dose of recent one year (P < 0.05). These results could indicate that low level exposure to ionizing radiation can induce unstable chromosome aberrations in blood lymphocytes

  7. [239Pu and chromosomal aberrations in human peripheral blood lymphocytes].

    Science.gov (United States)

    Okladnikova, N D; Osovets, S V; Kudriavtseva, T I

    2009-01-01

    The genome status in somatic cells was assessed using the chromosomal aberration (CA) test in peripheral blood lymphocytes from 194 plutonium workers exposed to occupational radiation mainly from low-transportable compounds of airborne 230Pu. Pu body burden at the time of cytogenetic study varied from values close to the method sensitivity to values multiply exceeding the permissible level. Standard (routine) methods of peripheral blood lymphocytes cultivation were applied. Chromatid- and chromosomal-type structural changes were estimated. Aberrations were estimated per 100 examined metaphase cells. The quantitative relationship between the CA frequency and Pu body burden and the absorbed dose to the lung was found. Mathematical processing of results was carried out based on the phenomenological model. The results were shown as theoretical and experimental curves. The threshold of the CA yield was 0.43 +/- 0.03 kBq (Pu body burden) and 6.12 +/- 1.20 cGy (absorbed dose to the lung).

  8. Mathematical Modeling of Carcinogenesis Based on Chromosome Aberration Data

    Institute of Scientific and Technical Information of China (English)

    Xiao-bo Li

    2009-01-01

    Objective: The progression of human cancer is characterized by the accumulation of genetic instability. An increasing number of experimental genetic molecular techniques have been used to detect chromosome aberrations. Previous studies on chromosome abnormalities often focused on identifying the frequent loci of chromosome alterations, but rarely addressed the issue of interrelationship of chromosomal abnormalities. In the last few years, several mathematical models have been employed to construct models of carcinogenesis, in an attempt to identify the time order and cause-and-effect relationship of chromosome aberrations. The principles and applications of these models are reviewed and compared in this paper. Mathematical modeling of carcinogenesis can contribute to our understanding of the molecular genetics of tumor development, and identification of cancer related genes, thus leading to improved clinical practice of cancer.

  9. Detection of epigenetic aberrations in the development of hepatocellular carcinoma.

    Science.gov (United States)

    Zhang, Yujing

    2015-01-01

    Hepatocellular carcinoma (HCC) is the third most common cause of cancer death worldwide. Hepatocarcinogenesis is a complex, multistep process. It is now recognized that HCC is a both genetic and epigenetic disease; genetic and epigenetic components cooperate at all stages of hepatocarcinogenesis. Epigenetic changes involve aberrant DNA methylation, posttranslational histone modifications and aberrant expression of microRNAs all of which can affect the expression of oncogenes, tumor suppressor genes and other tumor-related genes and alter the pathways in cancer development. Several risk factors for HCC, including hepatitis B and C virus infections and exposure to the chemical carcinogen aflatoxin B1 have been found to influence epigenetic changes. Their interactions could play an important role in the initiation and progression of HCC. Discovery and detection of biomarkers for epigenetic changes is a promising area for early diagnosis and risk prediction of HCC.

  10. Chromosomal Aberrations in Humans Induced by Urban Air Pollution

    DEFF Research Database (Denmark)

    Knudsen, Lisbeth E.; Norppa, Hannu; Gamborg, Michael O.;

    1999-01-01

    We have studied the influence of individual susceptibility factors on the genotoxic effects of urban air pollution in 106 nonsmoking bus drivers and 101 postal workers in the Copenhagen metropolitan area. We used the frequency of chromosomal aberrations in peripheral blood lymphocytes...... that long-term exposure to urban air pollution (with traffic as the main contributor) induces chromosome damage in human somatic cells. Low DNA repair capacity and GSTM1 and NAT2 variants associated with reduced detoxification ability increase susceptibility to such damage. The effect of the GSTM1 genotype......, which was observed only in the bus drivers, appears to be associated with air pollution, whereas the NAT2 genotype effect, which affected all subjects, may influence the individual response to some other common exposure or the baseline level of chromosomal aberrations....

  11. Beam dynamics in rf guns and emittance correction techniques

    Science.gov (United States)

    Serafini, Luca

    1994-02-01

    In this paper we present a general review of beam dynamics in a laser-driven rf gun. The peculiarity of such an accelerating structure versus other conventional multi-cell linac structures is underlined on the basis of the Panofsky-Wenzel theorem, which is found to give a theoretical background for the well known Kim's model. A basic explanation for some proposed methods to correct rf induced emittance growth is also derived from the theorem. We also present three emittance correction techniques for the recovery of space-charge induced emittance growth, namely the optimum distributed disk-like bunch technique, the use of rf spatial harmonics to correct spherical aberration induced by space charge forces and the technique of emittance filtering by clipping the electron beam. The expected performances regarding the beam quality achievable with different techniques, as predicted by scaling laws and simulations, are analyzed, and, where available, compared to experimental results.

  12. Algorithm 865

    DEFF Research Database (Denmark)

    Gustavson, Fred G.; Reid, John K.; Wasniewski, Jerzy

    2007-01-01

    variables, and the speed is usually better than that of the LAPACK algorithm that uses full storage (n2 variables). Included are subroutines for rearranging a matrix whose upper or lower-triangular part is packed by columns to this format and for the inverse rearrangement. Also included is a kernel...

  13. Single image non-uniformity correction using compressive sensing

    Science.gov (United States)

    Jian, Xian-zhong; Lu, Rui-zhi; Guo, Qiang; Wang, Gui-pu

    2016-05-01

    A non-uniformity correction (NUC) method for an infrared focal plane array imaging system was proposed. The algorithm, based on compressive sensing (CS) of single image, overcame the disadvantages of "ghost artifacts" and bulk calculating costs in traditional NUC algorithms. A point-sampling matrix was designed to validate the measurements of CS on the time domain. The measurements were corrected using the midway infrared equalization algorithm, and the missing pixels were solved with the regularized orthogonal matching pursuit algorithm. Experimental results showed that the proposed method can reconstruct the entire image with only 25% pixels. A small difference was found between the correction results using 100% pixels and the reconstruction results using 40% pixels. Evaluation of the proposed method on the basis of the root-mean-square error, peak signal-to-noise ratio, and roughness index (ρ) proved the method to be robust and highly applicable.

  14. HDL IMPLEMENTATION OF ALGEBRAIC SOFT DECISION ALGORITHM FOR RS CODES

    OpenAIRE

    M. Revathy; Saravanan, R.

    2013-01-01

    Reed Solomon (RS) codes are widely used to detect and correct data errors in transmission andstorage systems. Hence it is used in many digital communication and storage devices. In existing systemReformulated inversion less Burst error correcting (RiBC) algorithm is used. But it lacks in speed,throughput & area. To overcome this Algebraic Soft Decision (ASD) algorithm is proposed. This Proposedalgorithm is based on Unified VLSI architecture for correcting burst errors as well as random errors...

  15. Minimum mean square error method for stripe nonuniformity correction

    Institute of Scientific and Technical Information of China (English)

    Weixian Qian; Qian Chen; Guohua Gu

    2011-01-01

    @@ Stripe nonuniformity is very typical in line infrared focal plane (IRFPA) and uncooled starring IRFPA.We develop the minimum mean square error (MMSE) method for stripe nonuniformity correction (NUC).The goal of the MMSE method is to determine the optimal NUC parameters for making the corrected image the closest to the ideal image.%Stripe nonuniformity is very typical in line infrared focal plane (IRFPA) and uncooled starring IRFPA.We develop the minimum mean square error (MMSE) method for stripe nonuniformity correction (NUC).The goal of the MMSE method is to determine the optimal NUC parameters for making the corrected image the closest to the ideal image. Moreover, this method can be achieved in one frame, making it more competitive than other scene-based NUC algorithms. We also demonstrate the calibration results of our algorithm using real and virtual infrared image sequences. The experiments verify the positive effect of our algorithm.

  16. Study on geometric correction of airborne multiangular imagery

    Institute of Scientific and Technical Information of China (English)

    LIU; Qiang; (刘强); LIU; Qinhuo; (柳钦火); XIAO; Qing; (肖青); TIAN; Guoliang; (田国良)

    2002-01-01

    An automatic image matching algorithm, and its application to geometric correction of airborne multiangular remote sensed imagery, are presented in this paper. The image-matching algorithm is designed to find correct match for images containing localized geometric distortion and spectral variation. Mathematical tools such as wavelet decomposition, B-spline, and multi-variant correlation estimator are integrated in the frame of pyramidal matching. The simulated experiment and our practice in correcting airborne multiangular images show that the matching algorithm is robust to the few random abnormal points and can achieve subpixel match accuracy in most area of the image. After geometric correction and registration, multiangular observations for each ground pixel are extracted and sun/view geometry is also simultaneously derived.

  17. Aberrant Phenotype in Iranian Patients with Acute Myeloid Leukemia

    Directory of Open Access Journals (Sweden)

    Mehdi Jahedi

    2014-03-01

    Full Text Available Purpose: The aim of this study was to evaluate the incidence of aberrant phenotypes and possible prognostic value in peripheral and bone marrow blood mononuclear cells of Iranian patients with AML. Methods: 56 cases of de novo AML (2010-2012 diagnosed by using an acute panel of monoclonal antibodies by multiparametric flowcytometry. Immunophenotyping was done on fresh bone marrow aspirate and/or peripheral blood samples using the acute panel of MoAbs is stained with Phycoerythrin (PE /fluorescein isothiocyanate (FITC, Allophycocyanin (APC and Peridinin-chlorophyll protein complex (perCP. We investigated Co-expression of lymphoid-associated markers CD2, CD3, CD7, CD 10, CD19, CD20 and CD22 in myeloblasts. Results: Out of the 56 cases, 32 (57.1% showed AP. CD7 was positive in 72.7% of cases in M1 and 28.5% in M2 but M3 and M4 cases lacked this marker. We detected CD2 in 58.35 of M1cases, 21.40% of M2 cases, 33.3 of M3 and 20% of M5; but M4 patients lacked this marker. The CBC analysis demonstrated a wide range of haemoglobin concentration, Platelet and WBC count which varied from normal to anaemia, thrombocytopenia to thrombocytosis and leukopenia to hyper leukocytosis. Conclusions: Our findings showed that CD7 and CD2 were the most common aberrant marker in Iranian patients with AML. However, we are not find any significant correlation between aberrant phenotype changing and MRD in our population. Taken together, this findings help to provide new insights in to the investigation of other aberrant phenotypes that may play roles in diagnosis and therapeutic of AML.

  18. An integrative characterization of recurrent molecular aberrations in glioblastoma genomes

    OpenAIRE

    Sintupisut, Nardnisa; Liu, Pei-Ling; Yeang, Chen-Hsiang

    2013-01-01

    Glioblastoma multiforme (GBM) is the most common and malignant primary brain tumor in adults. Decades of investigations and the recent effort of the Cancer Genome Atlas (TCGA) project have mapped many molecular alterations in GBM cells. Alterations on DNAs may dysregulate gene expressions and drive malignancy of tumors. It is thus important to uncover causal and statistical dependency between ‘effector’ molecular aberrations and ‘target’ gene expressions in GBMs. A rich collection of prior st...

  19. Aberrant functional brain connectome in people with antisocial personality disorder

    OpenAIRE

    Yan Tang; Jun Long; Wei Wang(College of William and Mary); Jian Liao; Hua Xie; Guihu Zhao; Hao Zhang

    2016-01-01

    Antisocial personality disorder (ASPD) is characterised by a disregard for social obligations and callous unconcern for the feelings of others. Studies have demonstrated that ASPD is associated with abnormalities in brain regions and aberrant functional connectivity. In this paper, topological organisation was examined in resting-state fMRI data obtained from 32 ASPD patients and 32 non-ASPD controls. The frequency-dependent functional networks were constructed using wavelet-based correlation...

  20. Evaluation of corneal higher order aberrations in normal topographic patterns

    OpenAIRE

    Mirzajani, Ali; Aghataheri, Sattar; Ghoreishi, Mohammad; Jafarzadepour, Ebrahim; Mohammadinia, Mohadese

    2016-01-01

    Purpose This study reports the characteristics of corneal higher order aberrations (HOAs) in eyes with normal topographic pattern using the Pentacam scheimpflug system. Methods In this prospective, observational, comparative study, 165 eyes of 97 patients separated into five groups based on corneal topographic patterns were enrolled. All eyes received a comprehensive ophthalmologic examination including corneal tomographic analysis with the Pentacam system. Keratometry, corneal cylinder, and ...