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Sample records for abalone agency national

  1. Black abalone habitat suitability model for Channel Islands National Marine Sanctuary Biogeographic Assessment

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Office of National Marine Sanctuaries (ONMS) updates and revises the management plans for each of its 13 sanctuaries. This process, which is open to the public,...

  2. White abalone habitat suitability model for Channel Islands National Marine Sanctuary Biogeographic Assessment

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Marine Sanctuary Program (NMSP) updates and revises the management plans for each of its 13 sanctuaries. This process, which is open to the public,...

  3. National Association of Area Agencies on Aging

    Science.gov (United States)

    National Association of Area Agencies on Aging Search Member Login Forgot Password? Menu ABOUT n4a Mission, Vision & Work AAAs & Title VI Aging Programs Membership Board of Directors Staff Contact ...

  4. National Asset Management Agency Management of Loans

    OpenAIRE

    Buckley, John

    2012-01-01

    Report of the Comptroller and Auditor General National Asset Management Agency – Management of Loans I have, in accordance with the provisions of Section 9 of the Comptroller and Auditor General (Amendment) Act, 1993, carried out an examination of the arrangements for the management of loans by the National Asset Management Agency. I hereby submit my report on the above examination for presentation to Dáil Éireann pursuant to Section 11 of the said Act. John Buckley Comptroller...

  5. Lead behavior in abalone shell

    Science.gov (United States)

    Hirao, Yoshimitsu; Matsumoto, Akikazu; Yamakawa, Hiroshi; Maeda, Masaru; Kimura, Kan

    1994-08-01

    In order to gain information about the behavior of heavy metals in biological assimilation processes in a marine food chain and to investigate the possibility that lead pollution in a marine environment can be estimated by measurement of a small number of key materials from such a food chain, muscle and shell were analyzed from abalone ( Haliotis) from a shallow water locality in a Japanese coastal region. Lead concentrations in muscle were about 26 ppb for abalone of approximately 3 years old and decreased systematically with increasing age of animals sampled, to about 3.3 ppb for a specimen approximately 8 years old. Lead concentrations in shell material gradually decreased also, from 150 ppb to 82 ppb in the oldest specimen. The decrease of concentration in tissues with increasing age indicates that a mechanism for exclusion of lead during tissue growth becomes more efficient with age. Along the food chain in which abalone is the final stage, lead was enriched at the first stage, from seawater to algae, by a factor of 100. Lead was diminished at all subsequent stages of the chain. Tissue of artificially cultured abalone had four times higher lead values compared to abalone grown in natural conditions, and this appears to reflect the fact that lead concentration was three times higher in seawater in the cultured environment.

  6. National Nuclear Management and Control Agency (NNCA)

    International Nuclear Information System (INIS)

    Yoon, Wan Ki

    2006-01-01

    The National Nuclear Management and Control Agency (NNCA) is an independent agency for safeguards and material control for nuclear activities in the Republic of Korea. Formerly subordinate to the Korea Atomic Energy Research Institute (KAERI), it is temporarily associated with the Korea Institute of Nuclear Safety (KINS). In mid-2006 it will become fully independent. The NNCA is responsible for safeguards within the ROK, cooperates with the IAEA, and supports technical needs of the Ministry of Science and Technology (MOST). In addition, it has responsibilities in export controls and physical protection. In the future the NNCA expects to become a national 'think tank' for nuclear control and nonproliferation issues. This presentation enumerated the many responsibilities of the NNCA and explained the structure and staffing of the organization. (author)

  7. The Texts of the Agency's Agreements with the United Nations

    International Nuclear Information System (INIS)

    1959-01-01

    The texts of the following agreements and supplementary agreements between the Agency and the United Nations are reproduced in this document for the information of all Members of the Agency: I. A. Agreement Governing the Relationship Between the United Nations and the International Atomic Energy Agency; B. Protocol Concerning the Entry into Force of the Agreement between the United Nations and the International Atomic Energy Agency; II. Administrative Arrangement Concerning the Use of the United Nations Laissez-Passer by Officials of the International Atomic Energy Agency; and III. Agreement for the Admission of the International Atomic Energy Agency into the United Nations Joint Staff Pension Fund

  8. The Texts of the Agency's Agreements with the United Nations

    International Nuclear Information System (INIS)

    1959-01-01

    The texts of the following agreements and supplementary agreements between the Agency and the United Nations are reproduced in this document for the information of all Members of the Agency: I. A. Agreement Governing the Relationship Between the United Nations and the International Atomic Energy Agency; B. Protocol Concerning the Entry into Force of the Agreement between the United Nations and the International Atomic Energy Agency; II. Administrative Arrangement Concerning the Use of the United Nations Laissez-Passer by Officials of the International Atomic Energy Agency; and III. Agreement for the Admission of the International Atomic Energy Agency into the United Nations Joint Staff Pension Fund [ru

  9. The Texts of the Agency's Agreements with the United Nations

    International Nuclear Information System (INIS)

    1959-01-01

    The texts of the following agreements and supplementary agreements between the Agency and the United Nations are reproduced in this document for the information of all Members of the Agency: I. A. Agreement Governing the Relationship Between the United Nations and the International Atomic Energy Agency; B. Protocol Concerning the Entry into Force of the Agreement between the United Nations and the International Atomic Energy Agency; II. Administrative Arrangement Concerning the Use of the United Nations Laissez-Passer by Officials of the International Atomic Energy Agency; and III. Agreement for the Admission of the International Atomic Energy Agency into the United Nations Joint Staff Pension Fund [es

  10. Overexploitation of Abalone at Libong Island, Trang Province, Southern Thailand

    Directory of Open Access Journals (Sweden)

    Chanyut Sudtongkong

    2012-09-01

    Full Text Available Abalone is generally known as a fishery resource of high economic value. The wild abalone from Libong Island iswidely known for its potential as a cocktail-size and high-quality broodstock for hatcheries. The high market price andexternal demand have encouraged local fisherman to catch the wild abalone without proper management, resulting in a nearextinction crisis in the abalone population in this area. The present evaluation of abalone management at Libong Island,Trang Province, Thailand, was conducted using local user perceptions. Sixteen performance indicators included effectiveness indicators, equity indicators, and sustainable indicators. These were measured to determine whether the abalonemanagement activities had achieved the set objectives in terms of better conditions for abalone cultivation and sustainability.The results revealed that the abalone population has undergone degrading and decline due to lack of proper managementmeasures in this area. The findings suggest that practical management is needed for the abalone population at Libong Island.

  11. The Text of the Executing Agency Agreement between the Agency and the United Nations Special Fund

    International Nuclear Information System (INIS)

    1962-01-01

    The text of the Executing Agency Agreement between the Agency and the United Nations Special Fund, which was approved by the General Conference on 5 October 1961 and which entered into force on 29 November 1961 upon signature by the Director General of the Agency and the Managing Director of the Special Fund, is reproduced in this document for the information of all Members of the Agency

  12. Abalone farm discharges the withering syndrome pathogen into the wild

    Directory of Open Access Journals (Sweden)

    Kevin eLafferty

    2013-12-01

    Full Text Available An intracellular bacterium Candidatus Xenohaliotis californiensis, also called Withering-Syndrome Rickettsia-Like Organism (WS-RLO, is the cause of mass mortalities that are the chief reason for endangerment of black abalone (Haliotis cracherodii. Using a real-time PCR assay, we found that a shore-based abalone farm in Santa Barbara, California, discharged WS-RLO DNA into the ocean. Several other shore-based abalone farms discharge effluent into critical habitat for black abalone in California and this might affect the recovery of wild black abalone. Existing regulatory frameworks exist that could help protect wild species from pathogens released from shore-based aquaculture.

  13. The Texts of the Agency's Agreements with the United Nations

    International Nuclear Information System (INIS)

    1963-01-01

    The text of the Special Agreement extending the jurisdiction of the Administrative Tribunal of the United Nations International Atomic Energy Agency regarding the applications of officials of this organization alleging non-observance of the Regulations of the Pension Fund UN staff, comes into force October 18, 1963, is reproduced in this document for the information of all Members of the Agency [fr

  14. National Nanotechnology Initiative Investments by Agency and Program Component Area

    Data.gov (United States)

    Office of Science and Technology Policy, Executive Office of the President — Data represents National Nanotechnology Initiative investments by agency and program component area (PCA) from FY 2001 through FY 2010 (requested). While this data...

  15. First attempts to cryopreserve red abalone (Haliotis rufescens oocytes

    Directory of Open Access Journals (Sweden)

    Ramírez Torrez, A.

    2015-01-01

    Full Text Available Overall, few advances in the cryopreservation of complex cells such as oocytes, embryo or tissue have been registered and in less quantity have been reported for aquatic species. Abalone has high economic interest worldwide and the conservation of abalone germplasm may help to enhance its culture and develop repopulation programs. In this work, we reported the cytotoxic effect of two concentration of trehalose (0.2 and 0.4 M on red abalone oocytes incubated for 10, 15 and 20 min. Also, we reported the cryopreservation of red abalone oocytes using a 3-steps cryopreservation protocol and 5 thawing protocols. Significant differences on cytotoxic effect were found (p<0.01. However, none of the cryoprotectant was optimum to cryopreserve red abalone oocyte. In conclusion, it is necessary to find an appropriate method to dehydrate or make the cryoprotectant penetrate on the abalone oocyte before proceeding to cryopreservation.

  16. Heat inactivation of a norovirus surrogate in cell culture lysate, abalone meat, and abalone viscera.

    Science.gov (United States)

    Park, Shin Young; Bae, San-Cheong; Ha, Sang-Do

    2015-03-01

    The current study examined the effects of temperature and heat treatment duration on murine norovirus-1 (MNV-1) from both viral cell culture lysate (7-8 log10 PFU) and experimentally contaminated abalone meat and viscera (5-6 log10 PFU) as a model of human norovirus (NoV). MNV-1 titers in cell culture lysate, abalone meat, and abalone viscera were gradually reduced to 1.93-4.55, 1.79-3.00, and 2.26-3.26 log10 PFU/ml, respectively, after treatment at 70 °C for 1-10 min. Treatment at 85 °C for 1-5 min gradually reduced MNV-1 titers in abalone meat to 2.71-4.15 log10 PFU/ml. MNV-1 titers in abalone viscera were gradually reduced to 2.91-3.46 log10 PFU/ml after treatment at 85 °C for 1-3 min. No significant difference (P > 0.05) was found in MNV-1 titers in the abalone meat and viscera among treatment groups (70 °C for 5 min, 70 °C for 3 min, and 85 °C for 1 min). Complete inactivation of MNV-1 in cell culture lysate was determined at 85 °C for ≥1 min and 100 °C for ≥0.5 min. Complete inactivation of MNV-1 in abalone was determined at 100 °C for ≥0.5 min for meat, and 85 °C for 5 min and 100 °C for ≥0.5 min for viscera. At treatments at 70 °C, the Td-values (3 log reduction time) were significantly lower (P 0.05) between abalone meat (1.78) and abalone viscera (1.33) at treatments at 85 °C. This study suggests that 100 °C for ≥0.5 min could potentially be used to inactivate NoV in molluscan shellfishes, including viscera.

  17. Short Communication Towards an abalone weaning diet: evaluation ...

    African Journals Online (AJOL)

    Survival of post-settlement abalone when 'weaning' them from diatoms onto macroalgae/artificial feed remains unpredictable for farmers. It is hypothesised that spirulina algae, which are high in protein, may be a suitable feed ingredient for weaning abalone. Over a period of 27 days, the growth and survival of juvenile (4–6 ...

  18. Spionid polychaetes infesting cultured abalone Haliotis midae in ...

    African Journals Online (AJOL)

    CA Simon, A Ludford, S Wynne. Abstract. A study was conducted to identify and quantify the spionid polychaetes that infest cultured abalone Haliotis midae at aquaculture facilities on the west (Farm A), south (Farms B and C) and ... The abalone were infested by Dipolydora capensis, Polydora hoplura and a Boccardia sp.

  19. Short Communication Growth of post-weaning abalone Haliotis ...

    African Journals Online (AJOL)

    The effect of five formulated feeds supplemented with fresh wild seaweed on the growth of post-weaning juvenile abalone Haliotis midae (6–20 mm shell length) was investigated by means of a growth trial at a commercial abalone farm over a period of 11 months. The experiment included 10 diet treatments with two ...

  20. 76 FR 28960 - Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting

    Science.gov (United States)

    2011-05-19

    ... DEPARTMENT OF DEFENSE Office of the Secretary Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting AGENCY: National Defense Intelligence College, Defense Intelligence Agency, Department of Defense. ACTION: Notice of Closed Meeting. SUMMARY: Pursuant to the...

  1. 77 FR 32952 - Defense Intelligence Agency National Intelligence University Board of Visitors Closed Meeting

    Science.gov (United States)

    2012-06-04

    ... DEPARTMENT OF DEFENSE Office of the Secretary Defense Intelligence Agency National Intelligence University Board of Visitors Closed Meeting AGENCY: Department of Defense, Defense Intelligence Agency, National Intelligence University. ACTION: Notice of closed meeting. SUMMARY: Pursuant to the provisions of...

  2. 78 FR 32241 - Defense Intelligence Agency National Intelligence University Board of Visitors; Notice of Closed...

    Science.gov (United States)

    2013-05-29

    ... DEPARTMENT OF DEFENSE Office of the Secretary Defense Intelligence Agency National Intelligence University Board of Visitors; Notice of Closed Meeting AGENCY: National Intelligence University, Defense Intelligence Agency, Department of Defense. ACTION: Notice of closed meeting. SUMMARY: Pursuant to the...

  3. 75 FR 76423 - Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting

    Science.gov (United States)

    2010-12-08

    ... DEPARTMENT OF DEFENSE Office of the Secretary Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting AGENCY: National Defense Intelligence College, Defense Intelligence Agency, Department of Defense. ACTION: Notice of Closed Meeting. SUMMARY: Pursuant to the...

  4. Evidence of green fluorescent protein and growth hormone expression in red abalone (Haliotis rufescens larvae

    Directory of Open Access Journals (Sweden)

    Mancilla-Sánchez Edgar

    2017-02-01

    Full Text Available The red abalone Haliotis rufescens is a highly appreciated mollusk in the national and international markets. Due to its natural over-exploitation and low growth rate, several genetic improvements were made, however special efforts are needed to increase its production. This study presents transgenic abalone’s larvae expressing green fluorescent protein (GFP fused to Cobia (Rachycentron canadum Growth Hormone (GH using sperm media transgenesis technique (SMT, pAcGFP1-N vector under the control of cytomegalovirus (CMV promoter. Sperms were exposed to three voltages (0.5, 0.75 and 1.0 Kv using a micropulser electroporator (Bio-Rad®. The highest GFP-GH expression average (40% was obtained in abalone larvae at 0.75 v. GFP and GH transgenes were positively detected by PCR, western blot and confocal microscope, respectively.

  5. 78 FR 90 - Defense Intelligence Agency National Intelligence University Board of Visitors Closed Meeting

    Science.gov (United States)

    2013-01-02

    ... DEPARTMENT OF DEFENSE Office of the Secretary Defense Intelligence Agency National Intelligence University Board of Visitors Closed Meeting AGENCY: National Intelligence University, Defense Intelligence... hereby given that a closed meeting of the National Intelligence University Board of Visitors has been...

  6. Mortality of the abalone Haliotis mariae (Haliotidae: Mollusca in aquaculture

    Directory of Open Access Journals (Sweden)

    Gilha Yoon

    2015-01-01

    Full Text Available The Omani abalone, Haliotis mariae, is the only species of abalone found in Omani waters. Given the rarity of this species and the high price it can fetch on the market (US$ 150 kg-1 dry weight, the wild abalone fishery in the Dhofar region has been regarded as a valuable income source for the past decade. The present study was undertaken set to investigate the mortality of abalone held at the Mirbat Research Center, through bacteriological and histopathological based investigations and challenge tests. Only the adult wild abalone that had been kept for a year in the hatchery, visually, appeared to be clear of disease symptoms. Infected individuals typically were swollen around the mouth, had fluid tinged with blood, bubbles in the intestines, and, very weak adhesive strength. The foot area (muscle of diseased animals was noticeably very soft and individuals that were seen lying upside down on the bottom of the tank subsequently died. On dissection, the intestinal organs released bubbles and a foul smelling odour. Identification of the isolated bacteria using various identification methods indicated that individuals were infected with Staphylococcus sciuri. Histopathology of infected individuals revealed spongiosis of the tissues with evident bacterial infection. Neither of these histopathological conditions were seen in healthy abalone. The study concludes that the bacterium Staphylococcus sciuri may be the likely cause of abalone mortalities.

  7. Copernicus - Practice of Daily Life in a National Mapping Agency?

    Science.gov (United States)

    Wiatr, T.; Suresh, G.; Gehrke, R.; Hovenbitzer, M.

    2016-06-01

    Copernicus is an European system created for Earth observation and monitoring. It consists of a set of Earth observation satellites and in-situ sensors that provide geo-information that are used, through a set of Copernicus services, for applications related to the environment and global security. The main services of the Copernicus programme address six thematic areas: land, marine, atmosphere, climate change, emergency management and security. In Germany, there is a national service team of Copernicus service coordinators, who are responsible for the national development of the Copernicus services and for providing user-specific information about the Copernicus processes. These coordinators represent the contact points for all the programmes and services concerning their respective Copernicus theme. To publish information about Copernicus, national conferences and workshops are organised. Many people are involved in planning the continuous process of bringing the information to public authorities, research institutes and commercial companies. The Federal Agency for Cartography and Geodesy (Bundesamt für Kartographie und Geodäsie, BKG) is one such organisation, and is mainly responsible for the national land monitoring service of Copernicus. To make use of the freely available data from the Copernicus programme, the Federal Agency for Cartography and Geodesy is currently developing new applications and projects in the field of remote sensing and land monitoring. These projects can be used by other public authorities as examples on how to use the Copernicus data and services for their individual demands and requirements. Copernicus data and services are currently not very commonly used in the daily routine of the national mapping agencies, but they will soon be.

  8. Bringing the National Security Agency into the Classroom: Ethical Reflections on Academia-Intelligence Agency Partnerships.

    Science.gov (United States)

    Kampe, Christopher; Reid, Gwendolynne; Jones, Paul; S, Colleen; S, Sean; Vogel, Kathleen M

    2018-01-09

    Academia-intelligence agency collaborations are on the rise for a variety of reasons. These can take many forms, one of which is in the classroom, using students to stand in for intelligence analysts. Classrooms, however, are ethically complex spaces, with students considered vulnerable populations, and become even more complex when layering multiple goals, activities, tools, and stakeholders over those traditionally present. This does not necessarily mean one must shy away from academia-intelligence agency partnerships in classrooms, but that these must be conducted carefully and reflexively. This paper hopes to contribute to this conversation by describing one purposeful classroom encounter that occurred between a professor, students, and intelligence practitioners in the fall of 2015 at North Carolina State University: an experiment conducted as part of a graduate-level political science class that involved students working with a prototype analytic technology, a type of participatory sensing/self-tracking device, developed by the National Security Agency. This experiment opened up the following questions that this paper will explore: What social, ethical, and pedagogical considerations arise with the deployment of a prototype intelligence technology in the college classroom, and how can they be addressed? How can academia-intelligence agency collaboration in the classroom be conducted in ways that provide benefits to all parties, while minimizing disruptions and negative consequences? This paper will discuss the experimental findings in the context of ethical perspectives involved in values in design and participatory/self-tracking data practices, and discuss lessons learned for the ethics of future academia-intelligence agency partnerships in the classroom.

  9. Analysis of microbiota on abalone (Haliotis discus hannai) in South Korea for improved product management.

    Science.gov (United States)

    Lee, Min-Jung; Lee, Jin-Jae; Chung, Han Young; Choi, Sang Ho; Kim, Bong-Soo

    2016-10-03

    Abalone is a popular seafood in South Korea; however, because it contains various microorganisms, its ingestion can cause food poisoning. Therefore, analysis of the microbiota on abalone can improve understanding of outbreaks and causes of food poisoning and help to better manage seafood products. In this study, we collected a total of 40 abalones from four different regions in March and July, which are known as the maximum abalone production areas in Korea. The microbiota were analyzed using high-throughput sequencing, and bacterial loads on abalone were quantified by real-time PCR. Over 2700 species were detected in the samples, and Alpha- and Gammaproteobacteria were the predominant classes. The differences in microbiota among regions and at each sampling time were also investigated. Although Psychrobacter was the dominant genus detected on abalone in both March and July, the species compositions were different between the two sampling times. Five potential pathogens (Lactococcus garvieae, Yersinia kristensenii, Staphylococcus saprophyticus, Staphylococcus warneri, and Staphylococcus epidermidis) were detected among the abalone microbiota. In addition, we analyzed the influence of Vibrio parahaemolyticus infection on shifts in abalone microbiota during storage at different temperatures. Although the proportion of Vibrio increased over time in infected and non-infected abalone, the shifts of microbiota were more dynamic in infected abalone. These results can be used to better understand the potential of food poisoning caused by abalone consumption and manage abalone products according to the microbiota composition. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. 78 FR 47676 - Agency Information Collection Activities; Comment Request; National Professional Development...

    Science.gov (United States)

    2013-08-06

    ... DEPARTMENT OF EDUCATION [Docket No. ED-2013-ICCD-0100] Agency Information Collection Activities; Comment Request; National Professional Development Program: Grantee Performance Report AGENCY: Office of... of an existing information collection of a previously approved information collection. DATES...

  11. Automating the Photogrammetric Workflow in a National Mapping Agency

    Science.gov (United States)

    Holland, D.; Gladstone, C.; Sargent, I.; Horgan, J.; Gardiner, A.; Freeman, M.

    2012-07-01

    The goal of automating the process of identifying changes to topographic features in aerial photography, extracting the geometry of these features and recording the changes in a database, is yet to be fully realised. At Ordnance Survey, Britain's national mapping agency, research into the automation of these processes has been underway for several years, and is now beginning to be implemented in production systems. At the start of the processing chain is the identification of change - new buildings and roads being constructed, old structures demolished, alterations to field and vegetation boundaries and changes to inland water features. Using eCognition object-based image analysis techniques, a system has been developed to detect the changes to features. This uses four-band digital imagery (red, green, blue and near infra-red), together with a digital surface model derived by image matching, to identify all the topographic features of interest to a mapping agency. Once identified, these features are compared with those in the National Geographic Database and any potential changes are highlighted. These changes will be presented to photogrammetrists in the production area, who will rapidly assess whether or not the changes are real. If the change is accepted, they will manually capture the geometry and attributes of the feature concerned. The change detection process, although not fully automatic, cuts down the amount of time required to update the database, enabling a more efficient data collection workflow. Initial results, on the detection of changes to buildings only, showed a completeness value (proportion of the real changes that were found) of 92% and a correctness value (proportion of the changes found that were real changes) of 22%, with a time saving of around 50% when compared with the equivalent manual process. The completeness value is similar to those obtained by the manual process. Further work on the process has added vegetation, water and many other

  12. 77 FR 1945 - Agency Information Collection Activities: Proposed Collection; Comment Request, National Fire...

    Science.gov (United States)

    2012-01-12

    ...; Comment Request, National Fire Department Census AGENCY: Federal Emergency Management Agency, DHS. ACTION... collect data for the development and continuation of the National Fire Department Census. DATES: Comments..., Statistician, United States Fire Administration, National Fire Data Center, (301) 447-1154 for additional...

  13. Gradual Ordering in Red Abalone Nacre

    Energy Technology Data Exchange (ETDEWEB)

    Gilbert, P. U. P. A.; Metzler, Rebecca A.; Zhou, Dong; Scholl, Andreas; Doran, Andrew; Young, Anthony; Kunz, Martin; Tamura, Nobumichi; Coppersmith, Susan N.

    2008-09-03

    Red abalone (Haliotis rufescens) nacre is a layered composite biomineral that contains crystalline aragonite tablets confined by organic layers. Nacre is intensely studied because its biologically controlled microarchitecture gives rise to remarkable strength and toughness, but the mechanisms leading to its formation are not well understood. Here we present synchrotron spectromicroscopy experiments revealing that stacks of aragonite tablet crystals in nacre are misoriented with respect to each other. Quantitative measurements of crystal orientation, tablet size, and tablet stacking direction show that orientational ordering occurs not abruptly but gradually over a distance of 50 {micro}m. Several lines of evidence indicate that different crystal orientations imply different tablet growth rates during nacre formation. A theoretical model based on kinetic and gradual selection of the fastest growth rates produces results in qualitative and quantitative agreement with the experimental data and therefore demonstrates that ordering in nacre is a result of crystal growth kinetics and competition either in addition or to the exclusion of templation by acidic proteins as previously assumed. As in other natural evolving kinetic systems, selection of the fastest-growing stacks of tablets occurs gradually in space and time. These results suggest that the self-ordering of the mineral phase, which may occur completely independently of biological or organic-molecule control, is fundamental in nacre formation.

  14. NUTRITION REQUIREMENT OF CULTURED ABALONE POST LARVAE AND JUVENILES: A REVIEW

    Directory of Open Access Journals (Sweden)

    Wa Iba

    2008-06-01

    Full Text Available Abalone aquaculture attracts wide attention nowadays because of its high market value and depleted of wild stocks. China and Japan are the main producer of abalone from aquaculture followed by other countries such as New Zealand, Australia and US. Most of cultured abalone are temperate species but considerable research efforts have been made to culture tropical abalone in the Philippines, Thailand, and Indonesia. Most of abalone culture still depends on natural food but recent studies have been conducted to develop artificial diet for abalone. This will not only reduce wild harvest of macrolagae but also develop high nutrition diet at low cost. Successful abalone aquaculture is determined by correct nutrition supplement in the diet. As other cultured animal, abalone requires balanced nutrition of carbohydrate, protein, lipid, vitamins, and minerals. As herbivores, abalone can utilize carbohydrate efficiently as energy source and thus only requires low level of protein (range from 27%—40%. Lipid requirements range from 3%—5% while some minerals such as calcium and phosphorus in artificial feed are only needed in small amount, 0.5% of calcium in diets and 0.7% of phosphorus in the diet can improve the growth rate of abalone. There is not available information of vitamin upplementation in the diet but it is suggested that natural food meets the requirement.

  15. Concentration and retention of Toxoplasma gondii surrogates from seawater by red abalone (Haliotis rufescens)

    Science.gov (United States)

    Schott, Kristen C; Krusor, Colin; Tinker, M. Tim; Moore, James G.; Conrad, Patricia A.; Shapiro, Karen

    2016-01-01

    Small marine snails and abalone have been identified as high- and low-risk prey items, respectively, for exposure of threatened southern sea otters to Toxoplasma gondii, a zoonotic parasite that can cause fatal encephalitis in animals and humans. While recent work has characterized snails as paratenic hosts for T. gondii, the ability of abalone to vector the parasite has not been evaluated. To further elucidate why abalone predation may be protective against T. gondii exposure, this study aimed to determine whether: (1) abalone are physiologically capable of acquiring T. gondii; and (2) abalone and snails differ in their ability to concentrate and retain the parasite. Abalone were exposed to T. gondii surrogate microspheres for 24 h, and fecal samples were examined for 2 weeks following exposure. Concentration of surrogates was 2–3 orders of magnitude greater in abalone feces than in the spiked seawater, and excretion of surrogates continued for 14 days post-exposure. These results indicate that, physiologically, abalone and snails can equally vector T. gondii as paratenic hosts. Reduced risk of T. gondii infection in abalone-specializing otters may therefore result from abalone's high nutritional value, which implies otters must consume fewer animals to meet their caloric needs.

  16. Exploring National Environmental Policy Act processes across federal land management agencies

    Science.gov (United States)

    Marc J. Stern; Michael J. Mortimer

    2009-01-01

    Broad discretion is granted at all levels throughout federal land management agencies regarding compliance with the National Environmental Policy Act (NEPA). We explored the diversity of procedures employed in NEPA processes across four agencies, the USDA Forest Service, The USDI National Park Service and Bureau of Land Management, and the U.S. Army Corps of Engineers...

  17. 78 FR 71665 - Agency Information Collection Activities: Proposed Collection; Comment Request; National Youth...

    Science.gov (United States)

    2013-11-29

    ... Collection Activities: Proposed Collection; Comment Request; National Youth Gang Survey ACTION: 60-Day Notice.../Collection: National Youth Gang Survey. 3. Agency form number, if any, and the applicable component of the U... enforcement agencies. Other: None. Abstract: This collection will gather information related to youth and...

  18. 77 FR 64382 - Agency Information Collection (Nation-Wide Customer Satisfaction Surveys) Activities Under OMB...

    Science.gov (United States)

    2012-10-19

    ... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0712] Agency Information Collection (Nation-Wide Customer Satisfaction Surveys) Activities Under OMB Review AGENCY: Veterans Health Administration... ``OMB Control No. 2900-0712.'' SUPPLEMENTARY INFORMATION: Title: Nation-wide Customer Satisfaction...

  19. 75 FR 25320 - Agency Information Collection (Nation-wide Customer Satisfaction Surveys) Activities Under OMB...

    Science.gov (United States)

    2010-05-07

    ... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0712] Agency Information Collection (Nation-wide Customer Satisfaction Surveys) Activities Under OMB Review AGENCY: Veterans Health Administration... ``OMB Control No. 2900-0712.'' SUPPLEMENTARY INFORMATION: Title: Nation-wide Customer Satisfaction...

  20. The steadily increasing demand for South African abalone Haliotis ...

    African Journals Online (AJOL)

    denise

    of kelp beds, with potentially large ecological and commercial effects. The aims of this investigation were to estimate the potential harvest (standing stock) ...... DAY, E. 1998 — Ecological interactions between abalone (Haliotis midae) juveniles and sea urchins (Parechinus angulosus), off the south-west coast of South Africa.

  1. Abalone Haliotis spp. are in considerable demand worldwide ...

    African Journals Online (AJOL)

    spamer

    tauropine, as a result of condensation reactions be- tween pyruvate and the amino acids arginine, glycine, alanine and tauropine respectively, catalysed ...... 20: 567–570. JAMES, D. G. and J. OLLEY 1970 — Moisture and pH changes as criteria of freshness in abalone and their relationship to texture of the canned product.

  2. Abalone Haliotis spp. are in considerable demand worldwide ...

    African Journals Online (AJOL)

    spamer

    Abalone Haliotis spp. are in considerable demand worldwide, especially in the Far East. This has en- couraged industries that involve not only harvesting natural populations but also, as such populations have declined, setting up artificial cultures of appropriate species (Lo-Chai Chen 1990, Britz 1996, Knauer et al. 1996).

  3. Assessing the ecosystem effects of the abalone Haliotis midae from ...

    African Journals Online (AJOL)

    The South African abalone Haliotis midae is commercially exploited and seriously threatened by overfishing. This not only affects the species itself but potentially the functioning of the ecosystem because of associated changes in community structure. The nature of effects that can follow the loss or reduction of a species ...

  4. Book Review: Abalone of the World: Biology, Fisheries and Culture ...

    African Journals Online (AJOL)

    Book Title: Abalone of the World: Biology, Fisheries and Culture. Book Authors: Edited by S.A. Shepherd, M.J. Tegner & S.A. Guzman del Proo. Fishing News Books (Division of Blackwell Scientific. Publications Ltd.) Oxford, U.K. (1992). 608 pages. ISBN 0-85238-181-6.

  5. Book Review Abalone of the World: Biology, Fisheries and Culture

    African Journals Online (AJOL)

    Although this book originated from the First International. Symposium on Abalone Biology, which was held in La Paz,. Mexico in 1989, it is far more than a collection of symposium papers. The symposium papers are included in the volume but, in addition to this, the editors solicited review articles on several of the more ...

  6. Book Review Abalone of the World: Biology, Fisheries and Culture

    African Journals Online (AJOL)

    Edited by S.A. Shepherd, M.J. Tegner and S.A.. Guzman del Proo. Fishing News Books (Division of Blackwell Scientific. Publications ltd.) Oxford, U.K. (1992). 608 pages. Price: £65. ISBN 0-85238-181-6. Although this book originated from the First International. Symposium on Abalone Biology, which was held in La Paz,.

  7. Aquaculture-oriented genetic researches in abalone: Current status ...

    African Journals Online (AJOL)

    Taghwo

    2013-06-26

    Jun 26, 2013 ... *CS, Cold shock; HS, heat shock; HPS, hydropressure shock; CB, cytochlasin B; 6-DMAP, 6-dimethylaminopurine. ..... Induction of gynogenetic diploid by inhibiting second meiosis in the Pacific abalone. Nippon Suisan Gakkaishi 56: 1755-1763. Fujino K, Arai K, Kudo M, Suzuki T, Masumori M, Takahashi K ...

  8. The South African commercial abalone Haliotis midae fishery began ...

    African Journals Online (AJOL)

    spamer

    The South African commercial abalone Haliotis midae fishery began in 1949 and soon covered approxi- mately 580 km of coastline from Cape Columbine to. Quoin Point (Fig. 1). The catches in the 1960s were extremely high, and certainly greater than were sus- tainable, but fell dramatically in the 1970s. Although.

  9. Abalone water-soluble matrix for self-healing biomineralization of tooth defects

    Energy Technology Data Exchange (ETDEWEB)

    Wen, Zhenliang [Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou 350002 (China); Chen, Jingdi, E-mail: ibptcjd@fzu.edu.cn [Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou 350002 (China); Wang, Hailiang [The Affiliated Stomatological Hospital, Fujian Medical University, Fuzhou 350002 (China); Zhong, Shengnan; Hu, Yimin; Wang, Zhili [Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou 350002 (China); Zhang, Qiqing, E-mail: zhangqiq@126.com [Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou 350002 (China); Institute of Biomedical Engineering, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192 (China)

    2016-10-01

    Enamel cannot heal by itself if damaged. Hydroxyapatite (HAP) is main component of human enamel. Formation of enamel-like materials for healing enamel defects remains a challenge. In this paper, we successfully isolated the abalone water-soluble matrix (AWSM) with 1.53 wt% the abalone water-soluble protein (AWSPro) and 2.04 wt% the abalone water-soluble polysaccharide (AWSPs) from abandoned abalone shell, and self-healing biomineralization of tooth defects was successfully achieved in vitro. Based on X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), hot field emission scanning electron microscopy (HFESEM) and energy dispersive spectrometer (EDS) analysis, the results showed that the AWSM can efficiently induce remineralization of HAP. The enamel-like HAP was successfully achieved onto etched enamel's surface due to the presence of the AWSM. Moreover, the remineralized effect of eroded enamel was growing with the increase of the AWSM. This study provides a solution to the resource waste and environmental pollution caused by abandoned abalone shell, and we provides a new method for self-healing remineralization of enamel defects by AWSM and develops a novel dental material for potential clinical dentistry application. - Graphical abstract: In this paper, we successfully isolated the abalone water-soluble matrix (AWSM) with 1.53 wt% abalone water-soluble protein (AWSPro) and 2.04 wt% abalone water-soluble polysaccharide (AWSPs) from abandoned abalone shell, and self-healing biomineralization of tooth defects was successfully achieved in vitro by self-organized. Display Omitted - Highlights: • Provides a solution to the resource waste and environmental pollution caused by abandoned abalone shell. • The abalone shell water-soluble matrix contains protein and polysaccharide. • The abalone water-soluble matrix can efficiently induce remineralization of HAP by self-organized. • Achieved self-healing biomineralization of tooth defects in

  10. Complete mitochondrial genome of Pacific abalone (Haliotis discus hannai) from Korea.

    Science.gov (United States)

    Yang, Eun Chan; Nam, Bo-Hye; Noh, Seung-Jae; Kim, Young-Ok; Kim, Dong-Gyun; Jee, Young Ju; Park, Jun-Hyung; Noh, Jae Hoon; Yoon, Hwan Su

    2015-01-01

    We have sequenced and characterized the complete mitochondrial DNA of an economically and ecologically important Pacific abalone, Haliotis discus hannai (Haliotidae, Gastropoda). The mitogenome of the Pacific abalone is 16,886 nt total length with a 39.6% G+C composition. Thirty-seven genes were identified including 13 protein-coding, 2 rRNA and 22 tRNA genes. We compared the mitogenome of the Pacific abalone to a putative relative species, H. rubra.

  11. Management and Risk Assessment of Sabellid Polychaete Infestations in Abalone Mariculture Facilities

    OpenAIRE

    Kuris, Armand M.

    1996-01-01

    In October 1993, growers at some commercial abalone mariculture facilities (AMFs) in Southern California brought an interesting sabellid polychaete to our attention. The worm infested shells of cultured red abalone, Haliotis rufescens. Heavily infested abalone ceased growth. Their shells exhibited domed teratology often lacking respiratory holes. The worms appeared to bore into the shell. We discovered that all AMFs in California were infested; several were so heavily infest...

  12. Regulatory Powers of the National Agency Colombia Compra Eficiente

    Directory of Open Access Journals (Sweden)

    Jorge Santos Rodríguez

    2017-12-01

    Full Text Available This paper examines a recent decision by the State Council, in the matter of the regulatory powers of Colombia Compra Eficiente and its competence for issuing administrative rules in the subject of public procurement; in order to assess whether the manuals, guides and directives of this agency are formal or informal rules.

  13. 78 FR 6081 - Agency Information Collection Activities; Comment Request; National Student Loan Data System (NSLDS)

    Science.gov (United States)

    2013-01-29

    ...; Comment Request; National Student Loan Data System (NSLDS) AGENCY: Federal Student Aid (FSA), Department... of Collection: National Student Loan Data System (NSLDS). OMB Control Number: 1845-0035. Type of... data through the National Student Loan Data System (NSLDS) system from postsecondary schools, Perkins...

  14. 75 FR 49946 - National Drug Intelligence Center: Agency Information Collection Activities: Proposed Extension...

    Science.gov (United States)

    2010-08-16

    ... DEPARTMENT OF JUSTICE [OMB Number 1105-0087] National Drug Intelligence Center: Agency Information...), National Drug Intelligence Center (NDIC), will be submitting the following information collection request... Kevin M. Walker, General Counsel, National Drug Intelligence Center, Fifth Floor, 319 Washington Street...

  15. 75 FR 28034 - National Protection and Programs Directorate; Agency Information Collection Activities: United...

    Science.gov (United States)

    2010-05-19

    ... DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2010-0018] National Protection and Programs... Technology (US-VISIT) Biometric Data Collection at the Ports of Entry AGENCY: National Protection and... collection request: 1600-0006. SUMMARY: The Department of Homeland Security, National Protection and Programs...

  16. FORMULASI PAKAN BUATAN DENGAN BAHAN BAKU RUMPUT LAUT UNTUK PERTUMBUHAN ABALON Haliotis squamata

    Directory of Open Access Journals (Sweden)

    I Nyoman Adiasmara Giri

    2016-11-01

    Full Text Available Abalon merupakan salah satu jenis moluska laut yang memiliki potensi ekonomis untuk dikembangkan usaha budidayanya. Teknologi pembenihan abalon Haliotis squamata telah dikembangkan dan berhasil memproduksi benih secara massal. Selain benih, ketersediaan pakan yang sesuai sangat menentukan keberhasilan budidaya pembesaran abalon. Selain makan pakan segar berupa makroalga, abalon juga dapat menerima pakan buatan dengan baik. Penelitian ini bertujuan untuk mendapatkan formula pakan dengan bahan baku tepung rumput laut untuk pertumbuhan H. squamata. Tiga pakan percobaan diformulasi dengan proporsi tepung rumput laut Ulva sp., Gracilaria sp., dan Sargassum sp. yang berbeda dibuat berbentuk remah dengan kandungan protein dan lemak yang sama.  Sebagai kontrol digunakan pakan Gracilaria sp. segar asal tambak.  Sebanyak 16 buah bak beton berukuran 2,0 x 0,5 x 0,5 m3 dengan ketinggian air 25 cm dan dilengkapi dengan aerasi digunakan sebagai wadah percobaan.  Benih abalon hasil pembenihan di hatcheri dengan ukuran bobot 5,30 ± 1,07 g; panjang cangkang 3,35 ± 0,29 cm ditebar dengan kepadatan 388 ekor per bak.  Abalon diberi pakan percobaan 2 kali sehari selama 168 hari. Jumlah pakan disesuaikan dengan respons makan dari abalon. Percobaan dirancang dengan rancangan acak lengkap dengan 4 perlakuan pakan dan setiap perlakuan terdiri atas 4 ulangan.  Hasil percobaan menunjukkan bahwa pertumbuhan abalon yang diberi pakan buatan tidak berbeda nyata, tetapi pakan dengan proporsi tepung Ulva sp. 35% cenderung memberikan pertumbuhan yang lebih baik. Pertumbuhan abalon terbaik diperoleh pada perlakuan kontrol.  Kandungan protein daging abalon dipengaruhi oleh pakan percobaan. Kandungan protein daging abalon yang diberi pakan buatan signifikan lebih tinggi dibandingkan dengan kontrol.

  17. 77 FR 44266 - Agency Information Collection Activities: National Geological and Geophysical Data Preservation...

    Science.gov (United States)

    2012-07-27

    ... DEPARTMENT OF THE INTERIOR U.S. Geological Survey [USGS-GX12GL00DT70500] Agency Information Collection Activities: National Geological and Geophysical Data Preservation Program (NGGDPP) AGENCY: U.S. Geological Survey (USGS), Interior. ACTION: Notice of an extension of an existing information collection...

  18. Adoption Agency Perspectives on Lesbian and Gay Prospective Parents: A National Study.

    Science.gov (United States)

    Brodzinsky, David M.; Patterson, Charlotte J.; Vaziri, Mahnoush

    2002-01-01

    A nation-wide survey of adoption agencies examined policies, practices, and attitudes regarding lesbian/gay prospective adoptive parents. Attitudes and practices were found to vary as a function of agency religious affiliation. Many adoption professionals were willing to work with lesbian/gay prospective parents, and nearly 38 percent of…

  19. 78 FR 29731 - Agency Information Collection Activities; Proposed Collection; Comment Request; CPSC National...

    Science.gov (United States)

    2013-05-21

    ... communications efforts to achieve a greater impact on consumer behavior. The CPSC's activities aim to serve a... CONSUMER PRODUCT SAFETY COMMISSION [Docket No. CPSC-2013-0020] Agency Information Collection Activities; Proposed Collection; Comment Request; CPSC National Awareness Survey AGENCY: Consumer Product...

  20. 76 FR 13342 - Agency Information Collection Activities: Proposed Collection; Comment Request-National School...

    Science.gov (United States)

    2011-03-11

    ... from State child nutrition (CN) and education agencies, as well as local education agencies (LEAs). The.... Abstract: Direct certification was required of States and LEAs in the Child Nutrition and WIC... National School Lunch Program (NSLP) districts directly certified children in SNAP households; these...

  1. Differentially-Expressed Genes Associated with Faster Growth of the Pacific Abalone, Haliotis discus hannai.

    Science.gov (United States)

    Choi, Mi-Jin; Kim, Gun-Do; Kim, Jong-Myoung; Lim, Han Kyu

    2015-11-18

    The Pacific abalone Haliotis discus hannai is used for commercial aquaculture in Korea. We examined the transcriptome of Pacific abalone Haliotis discus hannai siblings using NGS technology to identify genes associated with high growth rates. Pacific abalones grown for 200 days post-fertilization were divided into small-, medium-, and large-size groups with mean weights of 0.26 ± 0.09 g, 1.43 ± 0.405 g, and 5.24 ± 1.09 g, respectively. RNA isolated from the soft tissues of each group was subjected to RNA sequencing. Approximately 1%-3% of the transcripts were differentially expressed in abalones, depending on the growth rate. RT-PCR was carried out on thirty four genes selected to confirm the relative differences in expression detected by RNA sequencing. Six differentially-expressed genes were identified as associated with faster growth of the Pacific abalone. These include five up-regulated genes (including one specific to females) encoding transcripts homologous to incilarin A, perlucin, transforming growth factor-beta-induced protein immunoglobulin-heavy chain 3 (ig-h3), vitelline envelope zona pellucida domain 4, and defensin, and one down-regulated gene encoding tomoregulin in large abalones. Most of the transcripts were expressed predominantly in the hepatopancreas. The genes identified in this study will lead to development of markers for identification of high-growth-rate abalones and female abalones.

  2. Human resource development, National Nuclear Energy Agency, Indonesia

    International Nuclear Information System (INIS)

    Karsono

    2007-01-01

    The development of an adequate national education and training infrastructure is the solution to solve the demand for qualified manpower to meet the national requirements of any nuclear program. Education and training activities were initiated in the year of 1981 with the forming of the Education and Training Center (ETC). The aging of manpower and the government policy on zero growth results in the discontinuity of knowledge transfer within the organization, and may be in the future of nuclear technology implementation. Since 1981 ETC has contributed to the training of its employees and industrial personnel through 800 training and involving around eleven thousand participants. Education and Training Center of BATAN accredited by BAPETEN as the nuclear training institutes for Radiation Protection Officer Certification, and in process of accreditation by National Accreditation Board as training institute for Non Destructive Test Personnel Certification. Annually ETC conduct 5 RPO training and 5 NDT Level I and 3 NDT Level II training. As shown in attached Table, there are at least 2999 RPO in Indonesia responsible for the safe operation of 4843 radioactive sources and 3741 radiation sources. Among the approximately 3700 employees of BATAN, national infrastructure has contributed to the education of 911 S1-graduates program, 24 master degree and 21 doctoral degree programs, while 46 bachelors degree, 201 master degree and 98 doctoral degree were taken overseas. Human resources have been identified on many occasions as being one of the most important elements for engaging in various types of nuclear applications. Major efforts must be directed towards attracting sufficient number of bright and interested students to the nuclear field for both current and future nuclear technology utilization. Therefore, it is necessary to transfer knowledge and know-how to the young generation for the sustainable development of nuclear science and technology. Courses in nuclear

  3. 76 FR 54001 - Agency Information Collection (National Practitioner Data Bank (NPDB) Regulations) Activity Under...

    Science.gov (United States)

    2011-08-30

    ... AFFAIRS Agency Information Collection (National Practitioner Data Bank (NPDB) Regulations) Activity Under... INFORMATION: Title: National Practitioner Data Bank Regulations (NPDB). OMB Control Number: OMB Control No....Regulations.gov ; or to VA's OMB Desk Officer, OMB Human Resources and Housing Branch, New Executive Office...

  4. 77 FR 37919 - Agency Information Collection Activities: Proposed Collection; Comments Requested: National...

    Science.gov (United States)

    2012-06-25

    ... perception/satisfaction of services. AEPD's strategy is based on a commitment to provide the kind of customer... Collection; Comments Requested: National Response Team Customer Satisfaction Survey ACTION: 60-Day Notice of... collection. (2) Title of the Form/Collection: National Response Team Customer Satisfaction Survey. (3) Agency...

  5. 77 FR 7171 - Agency Information Collection Activities: Proposed Collection; Comment Request, National Fire...

    Science.gov (United States)

    2012-02-10

    ...; Comment Request, National Fire Incident Reporting System (NFIRS) v5.0 AGENCY: Federal Emergency Management... National Fire Incident Reporting System (NFIRS) v5.0. The program provides a well established mechanism, using standardized reporting methods, to collect and analyze fire incident data at the Federal, State...

  6. Assessing Advanced Airway Management Performance in a National Cohort of Emergency Medical Services Agencies.

    Science.gov (United States)

    Wang, Henry E; Donnelly, John P; Barton, Dustin; Jarvis, Jeffrey L

    2018-05-01

    Although often the focus of quality improvement efforts, emergency medical services (EMS) advanced airway management performance has few national comparisons, nor are there many assessments with benchmarks accounting for differences in agency volume or patient mix. We seek to assess variations in advanced airway management and conventional intubation performance in a national cohort of EMS agencies. We used EMS data from ESO Solutions, a national EMS electronic health record system. We identified EMS emergency responses with attempted advanced airway management (conventional intubation, rapid sequence intubation, sedation-assisted intubation, supraglottic airway insertion, and cricothyroidotomy). We also separately examined cases with initial conventional intubation. We determined EMS agency risk-standardized advanced airway management and initial conventional intubation success rates by using mixed-effects regression models, fitting agency as a random intercept, adjusting for patient age, sex, race, cardiac arrest, or trauma status, and use of rapid sequence or sedation-assisted intubation, and accounting for reliability variations from EMS agency airway volume. We assessed changes in agency advanced airway management and initial conventional intubation performance rank after risk and reliability adjustment. We also identified high and low performers (reliability-adjusted and risk-standardized success confidence intervals falling outside the mean). During 2011 to 2015, 550 EMS agencies performed 57,209 advanced airway management procedures. Among 401 EMS agencies with greater than or equal to 10 advanced airway management procedures, there were a total of 56,636 procedures. Median reliability-adjusted and risk-standardized EMS agency advanced airway management success was 92.9% (interquartile range 90.1% to 94.8%; minimum 58.2%; maximum 99.0%). There were 56 advanced airway management low-performing and 38 high-performing EMS agencies. Among 342 agencies with

  7. Colombia an approach to create a national space agency

    Science.gov (United States)

    Arenales, O.

    Space exploration is a great human adventure: culturally, scientifically, technologically and industrially. Since the earliest of times, civilizations have been united in their awe of, and inspiration by, the cosmos, as testified in particularly by the peoples and cultures of the Central and South American continent in pre- Columbian times. Today, space systems have become an essential tool for the scientific disciplines related to the knowledge of the universe, including our own planet and its close or its remote environment. The main objective of this research is to explain the way in which Colombia, rich in myths and secular legends connecting mankind to the universe, must in the present tackle the issue of its development of space activities. The context in which it could be carried out is also described, along with a perspective of the current state of science and technology in the space sector on a global scale. Any modern nation is concerned with its independence, whether political, economic, or intellectual. That is why we support the concept of countries in the process of development becoming actively involved in the international space scene. Indeed, having limitations in industrial and technological exchange, we feel excluded today from key fields for our tomorrow. This paper thus proposes to demonstrate how in a time that can be regarded as one of the most serious crises in its history, Colombia could, in an atmosphere free from fratricidal conflicts, exploit its space matter capabilities. We do not limit our focus to the scientific field, but also consider the social, economic and cultural aspects. The results of this research delineate how Colombia could start a new optimistic phas e of its development, joining the international space programs within the framework of agreements among the regional governments in Latin America.

  8. Reduced disease in black abalone following mass mortality: Phage therapy and natural selection

    Science.gov (United States)

    VanBlaricom, Glenn R.

    2014-01-01

    Black abalone, Haliotis cracherodii, populations along the NE Pacific ocean have declined due to the rickettsial disease withering syndrome (WS). Natural recovery on San Nicolas Island (SNI) of Southern California suggested the development of resistance in island populations. Experimental challenges in one treatment demonstrated that progeny of disease-selected black abalone from SNI survived better than did those from naïve black abalone from Carmel Point in mainland coastal central California. Unexpectedly, the presence of a newly observed bacteriophage infecting the WS rickettsia (WS-RLO) had strong effects on the survival of infected abalone. Specifically, presence of phage-infected RLO (RLOv) reduced the host response to infection, RLO infection loads, and associated mortality. These data suggest that the black abalone: WS-RLO relationship is evolving through dual host mechanisms of resistance to RLO infection in the digestive gland via tolerance to infection in the primary target tissue (the post-esophagus) coupled with reduced pathogenicity of the WS-RLO by phage infection, which effectively reduces the infection load in the primary target tissue by half. Sea surface temperature patterns off southern California, associated with a recent hiatus in global-scale ocean warming, do not appear to be a sufficient explanation for survival patterns in SNI black abalone. These data highlight the potential for natural recovery of abalone populations over time and that further understanding of mechanisms governing host–parasite relationships will better enable us to manage declining populations.

  9. U.S. Environmental Protection Agency, Region 6 National Priorities List (NPL) Sites - 05/12/2014

    Data.gov (United States)

    U.S. Environmental Protection Agency — Point locations for sites in U.S. Environmental Protection Agency, Region 6 which are documented as being part of the National Priorities List as of May 12, 2014....

  10. U.S. Environmental Protection Agency, Region 6 National Priorities List (NPL) Boundaries - 05/12/2014

    Data.gov (United States)

    U.S. Environmental Protection Agency — Boundaries of sites in U.S. Environmental Protection Agency, Region 6 which are documented as being part of the National Priorities List as of May 12, 2014. The...

  11. The case for a United Nations verification agency. Disarmament under effective international control. Working paper 26

    International Nuclear Information System (INIS)

    Dorn, A.W.

    1990-07-01

    It is now universally recognized that arms control treaties should be effectively verified. The most objective, flexible and cost-effective means to verify the majority of multilateral treaties would be through a new agency under the United Nations. As a cooperative international effort to develop both the technology and the political framework for arms control verification, a United Nations verification agency (UNVA) would speed up and help secure the disarmament process by: verifying a number of existing and future treaties; investigating alleged breaches of treaties; and certifying, upon request, that voluntary arms control and confidence-building measures have been carried out. This paper presents the case for such a proposal, outlines a possible institutional configuration, considers the possibilities for growth and discusses the challenges facing the establishment of such an agency. (author). 16 refs., 1 tab

  12. 77 FR 51577 - Agency Information Collection Activities; Proposed Collection; Comments Requested: National...

    Science.gov (United States)

    2012-08-24

    ... previously approved collection. (2) Title of the Form/Collection: National Response Team Customer Satisfaction Survey. (3) Agency form number, if any, and the applicable component of the Department of Justice... Customer Satisfaction Survey ACTION: 30-Day notice of information collection under review. The Department...

  13. 77 FR 37869 - Agency Information Collection Activities: Proposed Collection; Comment Request-National Hunger...

    Science.gov (United States)

    2012-06-25

    ... organization World Hunger Year (WHY) of New York, NY. Section 26(d) was amended by section 112 of Public Law...: Proposed Collection; Comment Request--National Hunger Clearinghouse Database Form AGENCY: Food and... Hunger Clearinghouse. DATES: Written comments must be received on or before August 24, 2012. ADDRESSES...

  14. 76 FR 24031 - Board of Scientific Counselors, National Center for Environmental Health/Agency for Toxic...

    Science.gov (United States)

    2011-04-29

    ... Scientific Counselors, National Center for Environmental Health/Agency for Toxic Substances and Disease... Director updates; Program Response to BSC Program Peer Review of the Division of Environmental Hazards and... from 2:15 p.m. until 2:30 p.m. Contact Person for More Information: Sandra Malcom, Committee Management...

  15. Impacts of Psychological Science on National Security Agencies Post-9/11

    Science.gov (United States)

    Brandon, Susan E.

    2011-01-01

    Psychologists have been an integral part of national security agencies since World War I, when psychological science helped in personnel selection. A robust infrastructure supporting wider applications of psychology to military and intelligence problems developed further during World War II and the years following, primarily in the areas of…

  16. Antibiotic resistance monitoring in Vibrio spp. isolated from rearing environment and intestines of abalone Haliotis diversicolor.

    Science.gov (United States)

    Wang, R X; Wang, J Y; Sun, Y C; B L Yang; A L Wang

    2015-12-30

    546 Vibrio isolates from rearing seawater (292 strains) and intestines of abalone (254 strains) were tested to ten antibiotics using Kirby-Bauer diffusion method. Resistant rates of abalone-derived Vibrio isolates to chloramphenicol (C), enrofloxacin (ENX) and norfloxacin (NOR) were 40%) to kanamycin (KNA), furazolidone (F), tetracycline (TE), gentamicin (GM) and rifampin (RA). 332 isolates from seawater (n=258) and abalone (n=74) were resistant to more than three antibiotics. Peaked resistant rates of seawater-derived isolates to multiple antibiotics were overlapped in May and August. Statistical analysis showed that pH had an important effect on resistant rates of abalone-derived Vibrio isolates to RA, NOR, and ENX. Salinity and dissolved oxygen were negatively correlated with resistant rates of seawater-derived Vibrio isolates to KNA, RA, and PG. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Species Profiles. Life Histories and Environmental Requirements of Coastal Fishes and Invertebrates (Pacific Southwest). BLACK, GREEN, and RED ABALONES.

    Science.gov (United States)

    1985-03-01

    abalone landings abalones grow fast. Under optimal and ex-vissel value in California, conditions in a laboratory culture , 1965-1982 some juvenile red...Lithothamnion sp. Hymenena sp. Plocamium coccineum Tr i daea sp. Rhodymenia sp. Lithothamnion sp. Porphyra sp. Prionitis sp. Rhodymenia sp...Fecundacion artifi- Abalones, shells, and sea otters: cal y dessarrollo embrionario de dynamics of prey populations in Haliotis fulgens Philippi, 1845

  18. Status of abalone fishery and experiential mariculture as a resource conservation strategy in Carot, Anda, Pangasinan

    Directory of Open Access Journals (Sweden)

    Emmanuel C. Capinpin, Jr.

    2013-06-01

    Full Text Available The study described the abalone f ishery in Carot, Anda, Pangasinan to develop mariculture and to reseed a part of the harvest as a resource conservation strategy. The abalone fishery of Anda is artisanal or smallscale, typif ied by f ishers gleaning or free-diving on shallow rocky areas which are the typical habitat of abalone. Low densities of 1.67 to 8 individuals per 250 m2 were observed. Local f ishers have knowledge of productive f ishing areas. Hence, cage culture of abalone in these areas could be a viable resource conservation strategy as they serve as reproductive reserves to supply larvae for continued productivity of the f ishing grounds. Abalone mariculture following the Farmer Field School (FFS concept was explored to address both resource management and economic needs. As a resource enhancement activity, mariculture guarantees that cultured abalone are allowed to grow to maturity before harvested, while some are retained to restock a marine sanctuary. Sincemariculture makes possible the aggregation of individuals, the probability that fertilization would take place is increased. As supplemental source of livelihood, abalone is a high value commodity and its culture can help augment the income of f ishers. Small abalone (3-4 cm can be cultured further for 3-4 months to increase their size and weight. Mariculture should be done from November to May to avoid the rainy season and improve survivorship. The experiential activity was successful because it became a means for the f ishers to experienceresource management. Under the FFS, the researcher became a facilitator and mentored the cooperators in learning from their experience. The lessons sharpened the f ishers’ skills in observation, problem-solving, decision-making, and critical thinking. This enabled them to gain an appreciation of their resource.

  19. U.S. Environmental Protection Agency (EPA) National Priorities List (NPL) Sites Point Data with CIESIN Modifications, 2008

    Data.gov (United States)

    National Aeronautics and Space Administration — The U.S. Environmental Protection Agency (EPA) National Priorities List (NPL) Sites Point Data with CIESIN Modifications, 2008 is a modified version of the 2008 EPA...

  20. US Environmental Protection Agency National Coastal Assessment for Hawaii 2002: Water Quality, Fish Taxon, Sediment Chemistry Data (NODC Accession 0061250)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In 2002, the Environmental Protection Agency (EPA) Environmental Monitoring and Assessment Program (EMAP) National Coastal Assessment (NCA), in conjunction with...

  1. Using Local Ecological Knowledge and Environmental Education in Resource Management of Abalone in Carot, Anda, Pangasinan

    Directory of Open Access Journals (Sweden)

    Emmanuel C. Capinpin, Jr.

    2012-06-01

    Full Text Available The objectives of the present study were to (1 determine the local ecological knowledge (LEK of abalone gatherers through interviews and mentoring, and assess the correspondence between scientific information and LEK, so that areas where local knowledge may be most useful in resource management could be identified, and (2 to empower selected gatherers/farmers with knowledge and technical skills through environmental education to help develop or build their capacity to become sustainable resource managers. The LEK of abalone fishers was determined using three complementary approaches – group interview, individual interview, and mentoring sessions. Local fishers possess a wealth of knowledge about the interactions of species gained through many years of observations, and this knowledge may be useful in guiding biologists in ecological restoration or management regimes. Additionally, the fishers’ LEK, validated by modern scientific ecological findings, could be a source of important and effective ideas in resource management. The knowledge of the abalone gatherers about important abalone fishing grounds should help in pinpointing critical areas that need to be managed. Abalone mariculture in cages should be set up in these areas to routinely create dense breeding populations which can help in enhancing recovery and in providing fishers with a source of additional income. The continued enforcement of marine protected areas and the periodic release or reseeding of abalone in sanctuaries could also be considered viable resource management options. Other recommendations for resource management based on gathered local knowledge and lessons learned from the environmental education (EE seminars are also presented.

  2. Potential mechanisms of phthalate ester embryotoxicity in the abalone Haliotis diversicolor supertexta

    Energy Technology Data Exchange (ETDEWEB)

    Zhou Jin [L-304, Life Sciences Division, Graduate School at Shenzhen, Tsinghua University, Shenzhen University Town, Xili, Shenzhen City 518055 (China); Cai Zhonghua, E-mail: caizh@sz.tsinghua.edu.cn [L-304, Life Sciences Division, Graduate School at Shenzhen, Tsinghua University, Shenzhen University Town, Xili, Shenzhen City 518055 (China); Key Laboratory of Aquatic-Ecology, Tianjin Agricultural University, Lishui Road 112, Tianjin 300384 (China); Xing Kezhi [Key Laboratory of Aquatic-Ecology, Tianjin Agricultural University, Lishui Road 112, Tianjin 300384 (China)

    2011-05-15

    The effects and associated toxicological mechanisms of five phthalate esters (PAEs) on abalone embryonic development were investigated by exposing the embryos to a range of PAEs concentrations (0.05, 0.2, 2 and 10 {mu}g/mL). The results showed that PAEs could significantly reduce embryo hatchability, increase developmental malformations, and suppress the metamorphosis of abalone larvae. The possible toxicological mechanisms of PAEs to abalone embryos included, affecting the Na{sup +}-K{sup +}-pump and Ca{sup 2+}-Mg{sup 2+}-pump activities, altering the peroxidase (POD) level and the malondialdehyde (MDA) production, damaging the extraembryonic membranes structure, as well as disrupting endocrine-related genes (gpx, cyp3a, and 17{beta}-hsd 12) expression properties. Taken together, this work showed that PAEs adversely affected the embryonic ontogeny of abalone. The abilities of PAEs affecting the osmoregulation, inducing oxidative stress, damaging embryo envelope structure, and causing physiological homeostasis disorder, are likely to be a part of the common mechanisms responsible for their embryonic toxicity. - Highlights: > PAEs affected abalone hatchability, morphogenesis and metamorphosis behavior. > The toxicity of the five PAEs to embryogenesis was ranked as DBP > DEP > DMP > DOP > DEHP. > The osmoregulation disorder and oxidative damage are the potential mechanisms. - Potential mechanisms of PAEs on abalone embryogenesis are osmoregulation disorder, oxidative damage and physiological dysfunction.

  3. Social Media Platforms as a Tool for Sharing Emotions. A Perspective upon the National Security Agencies

    Directory of Open Access Journals (Sweden)

    Ramona-Diana LEON

    2016-05-01

    Full Text Available Emotions importance increases even more in the context of the national security agencies. Since their mission is to protect and defend the citizens against attacks and also to provide leadership and justice services to other agencies and partners, the aim of the information they post on social media should be twofold: on the one hand, it should reflect the attitudes, values and beliefs, supported by the institution, and on the other hand, it should have an impact on citizens feeling of security. But, do they manage to meet these demands? Are they focusing on impressing the audience or they concentrate on sharing specific emotions? Is it a marketing strategy or a knowledge strategy? Starting from these, the purpose of this research is to set a nexus between emotions and the use of social media by the national security organizations. In other words, we aim (i to determine the main types of emotions, (ii to establish whether these are shared within the social media platforms, (iii to identify the purpose for which the national security organizations use social media, (iv to determine whether social media could serve as Ba for the national security organizations. In order to achieve these objectives, we employ an ethic approach and develop a longitudinal study based on quantitative and qualitative content analysis. The results prove that social media platforms may serve as Ba since they appear as a shared space which fosters individual and collective knowledge creation and sharing. The national security agencies  use social media platforms for combining the classical four types of Ba: originating Ba (it shares its emotions, feelings and thoughts through its posts, interacting Ba (through the generated reactions and comments, it ensures the development of shared models and the conversion of tacit knowledge into explicit knowledge, cyber Ba (by fostering the virtual interaction among its followers and exercising Ba (by facilitating the creation of

  4. COPERNICUS – PRACTICE OF DAILY LIFE IN A NATIONAL MAPPING AGENCY?

    Directory of Open Access Journals (Sweden)

    T. Wiatr

    2016-06-01

    Full Text Available Copernicus is an European system created for Earth observation and monitoring. It consists of a set of Earth observation satellites and in-situ sensors that provide geo-information that are used, through a set of Copernicus services, for applications related to the environment and global security. The main services of the Copernicus programme address six thematic areas: land, marine, atmosphere, climate change, emergency management and security. In Germany, there is a national service team of Copernicus service coordinators, who are responsible for the national development of the Copernicus services and for providing user-specific information about the Copernicus processes. These coordinators represent the contact points for all the programmes and services concerning their respective Copernicus theme. To publish information about Copernicus, national conferences and workshops are organised. Many people are involved in planning the continuous process of bringing the information to public authorities, research institutes and commercial companies. The Federal Agency for Cartography and Geodesy (Bundesamt für Kartographie und Geodäsie, BKG is one such organisation, and is mainly responsible for the national land monitoring service of Copernicus. To make use of the freely available data from the Copernicus programme, the Federal Agency for Cartography and Geodesy is currently developing new applications and projects in the field of remote sensing and land monitoring. These projects can be used by other public authorities as examples on how to use the Copernicus data and services for their individual demands and requirements. Copernicus data and services are currently not very commonly used in the daily routine of the national mapping agencies, but they will soon be.

  5. Effect of abalone farming on sediment geochemistry in the Shallow Sea near Wando, South Korea

    Science.gov (United States)

    Kang, Jeongwon; Lee, Yeon Gyu; Jeong, Da Un; Lee, Jung Sick; Choi, Yang Ho; Shin, Yun Kyung

    2015-12-01

    Wando County has grown up to 93% of the total abalone produced in South Korea since the late 1990s; however, this production has been decreasing in recent years. The objectives of this study were to understand the potential contamination risks of abalone farming and to examine the influence of intensive abalone farming on sediment quality by analyzing grain-size composition, organic matter (total organic carbon (TOC), total nitrogen (TN), total sulfur (TS)) and heavy metal content, pH, and 210Pb geochronology. The results of organic matter analysis from surface and core sediment (length: 64 cm) showed that the area around the abalone farm had oxic marine-to-brackish conditions, but that the area directly below an abalone cage (location 7) had reductive conditions, with a C/S ratio of ~2. The average TN levels in the surface and core sediments were 0.25% and 0.29%, respectively, and this was predominantly due to the use of seaweed for feed. The low sediment pH (surface, 7.23; core, 7.04), indicates that acidification of the bottom sediment has gradually increased since the initiation of abalone farming and is likely due to the continuous accumulation of uneaten feed and feces. Heavy metal pollution was not apparent based on the examination of EF and Igeo, although the excess metal flux of Ni, Pb, Cu, Co, As, and Cd increased toward surface of the sediment core. These sediment changes may be caused by the rapid accumulation (sedimentation rate: 1.45 cm/year) of sludge discharged from the abalone farm and may be controlled by tidal currents, physiography, water depth, and tidal ranges.

  6. Genetic differentiation between fake abalone and genuine Haliotis species using the forensically informative nucleotide sequencing (FINS) method.

    Science.gov (United States)

    Ha, Wai Y; Reid, David G; Kam, Wan L; Lau, Yuk Y; Sham, Wing C; Tam, Silvia Y K; Sin, Della W M; Mok, Chuen S

    2011-05-25

    Abalones ( Haliotis species) are a popular delicacy and commonly preserved in dried form either whole or in slices or small pieces for consumption in Asian countries. Driven by the huge profit from trading abalones, dishonest traders may substitute other molluscan species for processed abalone, of which the morphological characteristics are frequently lost in the processed form. For protection of consumer rights and law enforcement against fraud, there is a need for an effective methodology to differentiate between fake and genuine abalone. This paper describes a method (validated according to the international forensic guidelines provided by SWGDAM) for the identification of fake abalone species using forensically informative nucleotide sequence (FINS) analysis. A study of the local market revealed that many claimed "abalone slice" samples on sale are not genuine. The fake abalone samples were found to be either volutids of the genus Cymbium (93%) or the muricid Concholepas concholepas (7%). This is the first report of Cymbium species being used for the preparation and sale as "abalone" in dried sliced form in Hong Kong.

  7. Epipodial Tentacle Gene Expression and Predetermined Resilience to Summer Mortality in the Commercially Important Greenlip Abalone, Haliotis laevigata.

    Science.gov (United States)

    Shiel, Brett P; Hall, Nathan E; Cooke, Ira R; Robinson, Nicholas A; Strugnell, Jan M

    2017-04-01

    "Summer mortality" is a phenomenon that occurs during warm water temperature spikes that results in the mass mortality of many ecologically and economically important mollusks such as abalone. This study aimed to determine whether the baseline gene expression of abalone before a laboratory-induced summer mortality event was associated with resilience to summer mortality. Tentacle transcriptomes of 35 greenlip abalone (Haliotis laevigata) were sequenced prior to the animals being exposed to an increase in water temperature-simulating conditions which have previously resulted in summer mortality. Abalone derived from three source locations with different environmental conditions were categorized as susceptible or resistant to summer mortality depending on whether they died or survived after the water temperature was increased. We detected two genes showing significantly higher expression in resilient abalone relative to susceptible abalone prior to the laboratory-induced summer mortality event. One of these genes was annotated through the NCBI non-redundant protein database using BLASTX to an anemone (Exaiptasia pallida) Transposon Ty3-G Gag Pol polyprotein. Distinct gene expression signatures were also found between resilient and susceptible abalone depending on the population origin, which may suggest divergence in local adaptation mechanisms for resilience. Many of these genes have been suggested to be involved in antioxidant and immune-related functions. The identification of these genes and their functional roles have enhanced our understanding of processes that may contribute to summer mortality in abalone. Our study supports the hypothesis that prestress gene expression signatures are indicative of the likelihood of summer mortality.

  8. KERAGAAN PERTUMBUHAN DAN REPRODUKSI ABALON Haliotis squamata Reeve (1846 TURUNAN KETIGA

    Directory of Open Access Journals (Sweden)

    Gusti Ngurah Permana

    2018-01-01

    Full Text Available Pengamatan pertumbuhan dan reproduksi abalon Haliotis squamata dilakukan di hatcheri Balai Besar Riset Budidaya Laut dan Penyuluhan Perikanan (BBRBLPP Gondol, Bali. Tujuan dari penelitian ini untuk memperoleh informasi tentang keragaan pertumbuhan dan performansi reproduksi abalon turunan ketiga. Induk H. squamata turunan kedua hasil seleksi yang digunakan untuk menghasilkan benih turunan ketiga mempunyai ukuran panjang cangkang 6,5-7,0 cm. Benih dipelihara dalam bak beton berukuran 2,5 m x 1,2 m x 1,0 m yang diberikan feeding plate sebagai substrat penempelan dan dilengkapi dengan sistem aerasi dan sistem air mengalir. Pakan yang diberikan pada awal pemeliharaan adalah diatom jenis Nitzschia sp. dan Melosira sp. yang telah ditumbuhkan terlebih dahulu pada feeding plate sebelum penebaran benih. Benih F-3 dipelihara sampai menjadi calon induk untuk diamati perkembangan reproduksinya. Pengambilan sampel pertumbuhan dilakukan setiap 10 hari. Pengamatan reproduksi dilakukan pada saat abalon mulai tumbuh gonad sampai matang gonad stadia-III. Hasil penelitian menunjukkan bahwa pertumbuhan abalon sangat dipengaruhi ketersediaan pakan pada plate terutama pada hari ke-50. Proporsi jantan-betina abalon F-3 (3,3:1 meningkat dibandingkan dengan F-0 dari alam (2,5:1 menunjukkan ketidakseimbangan jumlah individu yang dapat disebabkan oleh tekanan seleksi. Abalon turunan ketiga pada umur 16 bulan mulai matang gonad dan dapat digunakan sebagai induk untuk pemijahan. Observation on the growth and reproduction development of Haliotis squamata had been undertaken in the hatchery of the Institute for Mariculture Research and Development (IMRAD Gondol, Bali. The research was aimed to study of the growth and reproduction performance of filial-3 abalone in supporting seed production in hatchery. Larvae were obtained from natural spawning of filial-2 abalone broodstock with the length shell of 6.5-7.0 cm in the hatchery. Larvae were reared in 2.5 m x 1.2 m x 1.0 m

  9. Evaluating potential conservation conflicts between two listed species: sea otters and black abalone.

    Science.gov (United States)

    Raimondi, Peter; Jurgens, Laura J; Tinker, M Tim

    2015-11-01

    Population consequences of endangered species interacting as predators and prey have been considered theoretically and legally, but rarely investigated in the field. We examined relationships between spatially variable populations of a predator, the California sea otter, Enhydra lutris nereis, and a prey species, the black abalone, Haliotis cracherodii. Both species are federally listed under the Endangered Species Act and co-occur along the coast of California. We compared the local abundance and habitat distribution of black abalone at 12 sites with varying densities of sea otters. All of the populations of abalone we examined were in the geographic area currently unaffected by withering disease, which has decimated populations south of the study area. Surprisingly, our findings indicate that sea otter density is positively associated with increased black abalone density. The presence of sea otters also correlated with a shift in black abalone to habitat conferring greater refuge, which could decrease illegal human harvest. These results highlight the need for a multi-species approach to conservation management of the two species, and demonstrate the importance of using field-collected data rather than simple trophic assumptions to understand relationships between jointly vulnerable predator and prey populations.

  10. Preparation, characterisation and use for antioxidant oligosaccharides of a cellulase from abalone (Haliotis discus hannai) viscera.

    Science.gov (United States)

    Tao, Zhi-Peng; Sun, Le-Chang; Qiu, Xu-Jian; Cai, Qiu-Feng; Liu, Guang-Ming; Su, Wen-Jin; Cao, Min-Jie

    2016-07-01

    In China, abalone (Haliotis discus hannai) production is growing annually. During industrial processing, the viscera, which are abundant of cellulase, are usually discarded or processed into low-value feedstuff. Thus, it is of interest to obtain cellulase from abalone viscera and investigate its application for preparation of functional oligosaccharides. A cellulase was purified from the hepatopancreas of abalone by ammonium sulfate precipitation and two-steps column chromatography. The molecular weight of the cellulase was 45 kDa on SDS-PAGE. Peptide mass fingerprinting analysis yielded 103 amino acid residues, which were identical to cellulases from other species of abalone. Substrate specificity analysis indicated that the cellulase is an endo-1,4-β-glucanase. Hydrolysis of seaweed Porphyra haitanensis polysaccharides by the enzyme produced oligosaccharides with degree of polymerisation of two to four, whose monosaccharide composition was 58% galactose, 4% glucose and 38% xylose. The oligosaccharides revealed 2,2'-diphenyl-1-picrylhydrazyl free radical as well as hydrogen peroxide scavenging activity. It is feasible and meaningful to utilise cellulase from the viscera of abalone for preparation of functional oligosaccharides. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

  11. Evaluating potential conservation conflicts between two listed species: Sea otters and black abalone

    Science.gov (United States)

    Raimondi, Peter T.; Jurgens, Laura J.; Tinker, M. Tim

    2015-01-01

    Population consequences of endangered species interacting as predators and prey have been considered theoretically and legally, but rarely investigated in the field. We examined relationships between spatially variable populations of a predator, the California sea otter, Enhydra lutris nereis, and a prey species, the black abalone, Haliotis cracherodii. Both species are federally listed under the Endangered Species Act and co-occur along the coast of California. We compared the local abundance and habitat distribution of black abalone at 12 sites with varying densities of sea otters. All of the populations of abalone we examined were in the geographic area currently unaffected by withering disease, which has decimated populations south of the study area. Surprisingly, our findings indicate that sea otter density is positively associated with increased black abalone density. The presence of sea otters also correlated with a shift in black abalone to habitat conferring greater refuge, which could decrease illegal human harvest. These results highlight the need for a multi-species approach to conservation management of the two species, and demonstrate the importance of using field-collected data rather than simple trophic assumptions to understand relationships between jointly vulnerable predator and prey populations.

  12. KERAGAAN PERTUMBUHAN DAN VARIASI GENETIK ABALON Haliotis squamata Reeve (1846 HASIL SELEKSI F-1

    Directory of Open Access Journals (Sweden)

    Gusti Ngurah Permana

    2015-12-01

    Full Text Available Produksi benih abalon Haliotis squamata skala massal di hatcheri telah berhasil dilakukan di Balai Besar Penelitian dan Pengembangan Budidaya Laut Gondol, Bali. Permasalahan utama dalam budidaya abalon adalah pertumbuhan yang lambat. Keadaan tersebut diduga karena pengaruh faktor genetik dan lingkungan. Penelitian ini bertujuan mengetahui keragaan pertumbuhan dan variasi genetik abalon tumbuh cepat hasil seleksi individu. Hasil penelitian ini diketahui bahwa pembentukan populasi F-1 mempunyai pertumbuhan yang lebih baik dengan F-1 kontrol. Peningkatan bobot yang dicapai 22,15 g atau 17,93% lebih baik dibandingkan F-1 kontrol. Keragaman genetik F-1 terseleksi yang ditunjukkan dari nilai heterozigositas adalah (Ho. 0,023 terjadi penurunan 21,7% jika dibandingkan F-0. Hal ini dapat terjadi karena hilangnya beberapa allele dalam proses seleksi. Terdapat hubungan antara jumlah heterozigot pada lokus tertentu dengan pertumbuhan abalon. Hasil ini diharapkan dapat mendukung upaya meningkatkan produksi benih yang mempunyai performa fenotipe dan genotipe unggul sehingga dapat mendukung kegiatan budidaya abalon yang berkelanjutan.

  13. Involvement of Antizyme Characterized from the Small Abalone Haliotis diversicolor in Gonadal Development.

    Directory of Open Access Journals (Sweden)

    Wei-Dong Li

    Full Text Available The small abalone Haliotis diversicolor is an economically important mollusk that is widely cultivated in Southern China. Gonad precocity may affect the aquaculture of small abalone. Polyamines, which are small cationic molecules essential for cellular proliferation, may affect gonadal development. Ornithine decarboxylase (ODC and antizyme (AZ are essential elements of a feedback circuit that regulates cellular polyamines. This paper presents the molecular cloning and characterization of AZ from small abalone. Sequence analysis showed that the cDNA sequence of H. diversicolor AZ (HdiODCAZ consisted of two overlapping open reading frames (ORFs and conformed to the +1 frameshift property of the frame. Thin Layer chromatography (TLC analysis suggested that the expressed protein encoded by +1 ORF2 was the functional AZ that targets ODC to 26S proteasome degradation. The result demonstrated that the expression level of AZ was higher than that of ODC in the ovary of small abalone. In addition, the expression profiles of ODC and AZ at the different development stages of the ovary indicated that these two genes might be involved in the gonadal development of small abalone.

  14. Priorities in national space strategies and governance of the member states of the European Space Agency

    Science.gov (United States)

    Adriaensen, Maarten; Giannopapa, Christina; Sagath, Daniel; Papastefanou, Anastasia

    2015-12-01

    The European Space Agency (ESA) has twenty Member States with a variety of strategic priorities and governance structures regarding their space activities. A number of countries engage in space activities exclusively though ESA, while others have also their own national space programme. Some consider ESA as their prime space agency and others have additionally their own national agency with respective programmes. The main objective of this paper is to provide an up-to date overview and a holistic assessment of strategic priorities and the national space governance structures in 20 ESA Member States. This analysis and assessment has been conducted by analysing the Member States public documents, information provided at ESA workshop on this topic and though unstructured interviews. The paper is structured to include two main elements: priorities and trends in national space strategies and space governance in ESA Member States. The first part of this paper focuses on the content and analysis of the national space strategies and indicates the main priorities and trends in Member States. The priorities are categorised with regards to technology domains, the role of space in the areas of sustainability and the motivators that boost engagement in space. These vary from one Member State to another and include with different levels of engagement in technology domains amongst others: science and exploration, navigation, Earth observation, human space flight, launchers, telecommunications, and integrated applications. Member States allocate a different role of space as enabling tool adding to the advancement of sustainability areas including: security, resources, environment and climate change, transport and communication, energy, and knowledge and education. The motivators motivating reasoning which enhances or hinders space engagement also differs. The motivators identified are industrial competitiveness, job creation, technology development and transfer, social benefits

  15. U.S. Environmental Protection Agency, Region 6 National Priorities List (NPL) Boundaries - 05/12/2014

    Science.gov (United States)

    Boundaries of sites in U.S. Environmental Protection Agency, Region 6 which are documented as being part of the National Priorities List as of May 12, 2014. The locations were determined by U.S. Environmental Protection Agency, Region 6 Superfund RPMs.

  16. U.S. Environmental Protection Agency, Region 6 National Priorities List (NPL) Sites - 05/12/2014

    Science.gov (United States)

    Point locations for sites in U.S. Environmental Protection Agency, Region 6 which are documented as being part of the National Priorities List as of May 12, 2014. The locations were determined by U.S. Environmental Protection Agency, Region 6 Superfund RPMs.

  17. Aid Agency Influence in National Education Policy-Making: A Case from Nepal's "Education for All" Movement

    Science.gov (United States)

    Bhatta, Pramod

    2011-01-01

    This article explores the nexus between foreign aid and Nepal's primary education in order to understand how aid agencies affect national educational development. It argues that after 1990, when global education targets provided the basic framework for all donor agency funding to primary education and the subsequent use of a sector-wide approach…

  18. Isolation, identification, and antioxidant activity of polysaccharides from the shell of abalone (Haliotis discus hannai Ino).

    Science.gov (United States)

    Wang, Z L; Liang, H B; Guo, W; Peng, Z F; Chen, J D; Zhang, Q Q

    2014-07-04

    In this study, two antioxidative substances, a homogeneous polysaccharide [abalone shell polysaccharide (ASP-1), corresponding to the first peak by size exclusion chromatography] and a non-polysaccharide compound [abalone shell compound (ACS-2), corresponding to the second peak by size exclusion chromatography], were extracted from the abalone (Haliotis discus hannai Ino) shell. We primarily focused on the investigation of ASP-1. As a heteropolysaccharide, ASP-1 is comprised of 9.3% uronic acid and 86.4% saccharide, the latter including mannose, ribose, rhamnose, glucose, galactose, arabinose, and two unknown monosaccharides, NO1 and NO2, with a mass ratio of 9.5:10.1:2.2:18.2:21.8:5.5:16.5:16.2. The antioxidant activity assays indicated that 5.0 mg/mL ASP-1 has significant scavenging effects on superoxide radicals (86.2%) compared to the positive control of ascorbic acid (95.6%).

  19. Biokinetic behavior of Tc in the red abalone, Haliotis rufescens: a reassessment

    International Nuclear Information System (INIS)

    Beasley, T.M.; Lorz, H.V.; Gonor, J.J.

    1981-01-01

    The biokinetic behavior of /sup 95m/Tc in the red abalone, Haliotis rufescens, is reviewed in light of recent experiments on other molluscs. Additional experimentation has confirmed that, when uptake is directly from labeled seawater, abalone exhibit concentration factors in excess of 100. Bivalve molluscs under the same experimental conditions have concentration factors that do not exceed 2. However, uptake and loss kinetics cannot be described by a single compartment model as had been previously advanced. Assimilation of /sup 95m/Tc by the abalone following a single feeding of labeled macroalga, Nereocystis pyrifera, is high (approx. 45%) and loss kinetics are similar to those observed following direct uptake from seawater

  20. [The Brazilian National Health Surveillance Agency performance evaluation at the management contract model].

    Science.gov (United States)

    Moreira, Elka Maltez de Miranda; Costa, Ediná Alves

    2010-11-01

    The Brazilian National Health Surveillance Agency (Anvisa) is supervised by the Ministry of Health by means of a management contract, a performance evaluation tool. This case study was aimed at describing and analyzing Anvisa's performance evaluation model based on the agency's institutional purpose, according to the following analytical categories: the management contract formalization, evaluation tools, evaluators and institutional performance. Semi-structured interviews and document analysis revealed that Anvisa signed only one management contract with the Ministry of Health in 1999, updated by four additive terms. The Collegiate Board of Directors and the Advisory Center for Strategic Management play the role of Anvisa's internal evaluators and an Assessing Committee, comprising the Ministry of Health, constitutes its external evaluator. Three phases were identified in the evaluation model: the structuring of the new management model (1999-2000), legitimation regarding the productive segment (2001-2004) and widespread legitimation (2005). The best performance was presented in 2000 (86.05%) and the worst in 2004 (40.00%). The evaluation model was shown to have contributed little towards the agency's institutional purpose and the effectiveness measurement of the implemented actions.

  1. Transcriptional responses of metallothionein gene to different stress factors in Pacific abalone (Haliotis discus hannai).

    Science.gov (United States)

    Lee, Sang Yoon; Nam, Yoon Kwon

    2016-11-01

    A novel metallothionein (MT) gene from the Pacific abalone H. discus hannai was characterized and its mRNA expression patterns (tissue distribution, developmental expression and differential expression in responsive to various in vivo stimulatory treatments) were examined. Abalone MT shares conserved structural features with previously known gastropod orthologs at both genomic (i.e., tripartite organization) and amino acid (conserved Cys motifs) levels. The 5'-flanking regulatory region of abalone MT gene displayed various transcription factor binding motifs particularly including ones related with metal regulation and stress/immune responses. Tissue distribution and basal expression patterns of MT mRNAs indicated a potential association between ovarian MT expression and sexual maturation. Developmental expression pattern suggested the maternal contribution of MT mRNAs to embryonic and early larval developments. Abalone MT mRNAs could be significantly induced by various heavy metals in different tissues (gill, hepatopancreas, muscle and hemocyte) in a tissue- and/or metal-dependent fashion. In addition, the abalone MT gene was highly modulated in responsive to other non-metal, stimulatory treatments such as immune challenge (LPS, polyI:C and bacterial injections), hypoxia (decrease from normoxia 8 ppm-2 ppm), thermal elevation (increase from 20 °C to 30 °C), and xenobiotic exposure (250 ppb of 17α-ethynylestradiol and 0.25 ppb of 2,3,7,8-tetrachlorodibenzodioxin) where differential expression patterns were toward either up- or down-regulation depending on types of stimulations and tissues examined. Taken together, our results highlight that MT is a multifunctional effector playing in wide criteria of cellular pathways especially associated with development and stress responses in this abalone species. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Genomic Characterization of a Novel Phage Found in Black Abalone (Haliotis cracherodii) Infected with Withering Syndrome

    Science.gov (United States)

    Closek, C. J.; Langevin, S.; Burge, C. A.; Crosson, L.; White, S.; Friedman, C. S.

    2016-02-01

    Withering syndrome (WS), caused by the bacterium Candidatus Xenohaliotis californiensis, a Rickettsia-like organism (RLO), infects many species of abalone. Black abalone (Haliotis cracherodii), one of two endangered species of abalone, has experienced high population losses along the California coast due to WS. Recently, we observed reduced pathogenicity and mortality events in RLO-infected abalone when a novel bacteriophage (phage) was also present. To better understand phage-bacterium dynamics and develop more informative diagnostic tools, we sequenced the genome of the novel phage associated with the RLO responsible for WS. Metagenomic sequencing libraries were prepared with extracted genomic DNA from two experimentally infected H. cracherodii and phage sequences were enriched using hydroxyapatite chromatography normalization. Normalized libraries were individually barcoded and sequenced with Illumina MiSeq. Raw sequence reads were processed using VIrominer and de novo assembly produced one single phage-like contig (35.7Kb) from the experimentally infected abalone. This highly divergent genome had closest homology with a virus associated with abalone shriveling syndrome (SS). Of the 34 predicted ORFs, overlapping homology with the SS virus ranged from 20-72%, demonstrating the phage sequenced is genetically distinct from any known phage. The phage-like sequences represented a significant portion of the total reads sequenced ( 2 million of the 12 million paired-end reads; 17%) and we obtained 94,000X coverage across the novel phage genome. Beyond characterization of this novel phage, which appears to reduce pathogenicity of the RLO, the genome enabled us to develop quantitative PCR and in situ hybridization assays as diagnostic tools. These tools allow us to detect and quantify this phage in the endangered H. cracherodii.

  3. Public Health Agencies' level of engagement in and perceived barriers to PHAB National Voluntary Accreditation.

    Science.gov (United States)

    Shah, Gulzar H; Leep, Carolyn J; Ye, Jiali; Sellers, Katie; Liss-Levinson, Rivka; Williams, Karmen S

    2015-01-01

    This study examines local health departments' (LHDs') and state health agencies' (SHAs') engagement, LHDs' perceived barriers, and factors associated with level of engagement in accreditation. The study design is observational, cross-sectional, and based on census design surveys of all state and local health departments. Data from the National Association of County & City Health Officials' 2013 profile of LHDs and the Association of State and Territorial Health Officials' 2012 profile of SHAs were analyzed in 2014. Logistic regression was performed with 2 levels of engagement as the outcome variable. Six percent of LHDs and 27% of SHAs had either submitted an application or statement of intent, whereas 15% of LHDs and 4% of SHAs had decided not to pursue accreditation. Significant factors associated with higher level of LHD engagement in accreditation included population size of the LHD jurisdiction, state and shared governance (vs local), MD degree of top executive, absence of a local board of health, LHD's collaboration with other organizations, per capita expenditures, and performance of 2 of the Public Health Accreditation Board accreditation prerequisites, namely, a community health improvement plan and an agency-wide strategic plan. The most frequently reported reasons for LHDs not pursuing accreditation were the time/effort required for accreditation exceeding the benefits (72%), the fee being too high (54%), and the standards exceeding the capacity of their LHD (39%). Accreditation is expected to provide pathways to accountability, consistency, and better fit between community needs and public health services. National strategies targeting rapid diffusion of accreditation among public health agencies should include elements that address the needs of LHDs with varying degrees of intent to pursue accreditation.

  4. Abalone visceral extract inhibit tumor growth and metastasis by modulating Cox-2 levels and CD8+ T cell activity

    Directory of Open Access Journals (Sweden)

    II Kim Jae

    2010-10-01

    Full Text Available Abstract Background Abalone has long been used as a valuable food source in East Asian countries. Although the nutritional importance of abalone has been reported through in vitro and in vivo studies, there is little evidence about the potential anti-tumor effects of abalone visceral extract. The aim of the present study is to examine anti-tumor efficacy of abalone visceral extract and to elucidate its working mechanism. Methods In the present study, we used breast cancer model using BALB/c mouse-derived 4T1 mammary carcinoma and investigated the effect of abalone visceral extract on tumor development. Inhibitory effect against tumor metastasis was assessed by histopathology of lungs. Cox-2 productions by primary and secondary tumor were measured by real-time RT-PCR and immunoblotting (IB. Proliferation assay based on [3H]-thymidine incorporation and measurement of cytokines and effector molecules by RT-PCR were used to confirm tumor suppression efficacy of abalone visceral extract by modulating cytolytic CD8+ T cells. The cytotoxicity of CD8+ T cell was compared by JAM test. Results Oral administration of abalone visceral extract reduced tumor growth (tumor volume and weight and showed reduced metastasis as confirmed by decreased level of splenomegaly (spleen size and weight and histological analysis of the lung metastasis (gross analysis and histological staining. Reduced expression of Cox-2 (mRNA and protein from primary tumor and metastasized lung was also detected. In addition, treatment of abalone visceral extract increased anti-tumor activities of CD8+ T cells by increasing the proliferation capacity and their cytolytic activity. Conclusions Our results suggest that abalone visceral extract has anti-tumor effects by suppressing tumor growth and lung metastasis through decreasing Cox-2 expression level as well as promoting proliferation and cytolytic function of CD8+ T cells.

  5. 75 FR 70365 - Agency Information Collection (Follow-Up Study of a National Cohort of Gulf War and Gulf Era...

    Science.gov (United States)

    2010-11-17

    ... (Follow-Up Study of a National Cohort of Gulf War and Gulf Era Veterans) Activity Under OMB Review AGENCY...).'' SUPPLEMENTARY INFORMATION: Titles: Follow-Up Study of a National Cohort of Gulf War and Gulf Era Veterans, VA..., will help VA to assess the health of Gulf War veterans who were exposed to a variety of environmental...

  6. 41 CFR 102-77.25 - Do Federal agencies have responsibilities to provide national visibility for Art-in-Architecture?

    Science.gov (United States)

    2010-07-01

    ... responsibilities to provide national visibility for Art-in-Architecture? 102-77.25 Section 102-77.25 Public... MANAGEMENT REGULATION REAL PROPERTY 77-ART-IN-ARCHITECTURE Art-in-Architecture § 102-77.25 Do Federal agencies have responsibilities to provide national visibility for Art-in-Architecture? Yes, Federal...

  7. Charges Made by the National Federation of the Blind Against the National Accreditation Council for Agencies Serving the Blind and Visually Handicapped.

    Science.gov (United States)

    Comptroller General of the U.S., Washington, DC.

    Presented is a report submitted by the General Accounting Office (GAO) concerning its investigation of charges made by the National Federation of the Blind (NFB) against the National Accreditation Council for Agencies Serving the Blind and Visually Handicapped (NAC). It is explained that the GAO reviewed NFB allegations that the NAC does not act…

  8. The UK experience: the National Patient Safety Agencyís Patient Safety Observatory

    Directory of Open Access Journals (Sweden)

    Sarah Scobie

    2005-12-01

    Full Text Available

    The National Patient Safety Agency (NPSA was set up in 2001 in order to make changes at a national level, and lead work on improving patient safety in England and Wales. A core function of the NPSA is to identify trends and patterns in patient safety problems, using its own National Reporting and Learning System (NRLS and data from other sources.

    Almost all reports to the NRLS come directly from local risk management systems; staff can also report directly to the NPSA via an electronic form. By the end of August 2005, nearly 230,000 incidents had been reported to the NRLS; 76% of these were reported from acute/general hospitals.

    The analysis of data in the NRLS is a function of the NPSA’s Patient Safety Observatory (PSO, which has been established to quantify, characterise and prioritise patient safety issues in order to support the NHS in making healthcare safer. The PSO works with key national organisations which hold data relevant to patient safety, such as healthcare regulators, patient’s organisations, clinical negligence bodies and national information and statistics functions. Triangulating information from different data sources enables a fuller picture of the nature and severity of patient safety incidents to be obtained. The key challenges for the PSO are to strengthen the quality of NRLS data, extend the ways in which feedback from the NRLS is provided, and continue to develop methods and tools for the systematic analysis of the huge volumes of incidents reported to the NRLS.

  9. From untargeted LC-QTOF analysis to characterisation of opines in abalone adductor muscle: Theory meets practice.

    Science.gov (United States)

    Venter, Leonie; Jansen van Rensburg, Peet J; Loots, Du Toit; Vosloo, Andre; Lindeque, Jeremie Zander

    2017-12-15

    Abalone have a unique ability to use pyruvate, various amino acids and dehydrogenases, to produce opines as means to prevent the accumulation of NADH during anaerobic conditions. In this study, the theoretical masses, formulae and fragment patterns of butylated opines were used to predict which of these compounds could be found in the abalone adductor muscle using untargeted liquid chromatography quadrupole time-of flight-mass spectrometry. These findings were validated using synthesised opine standards. In essence alanopine, lysopine, strombine and tauropine produced in abalone adductor muscle could be characterised using the highest identification confidence levels. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Status of contamination monitoring in radiation activities of National Atomic Energy Agency (NAEA) in Indonesia

    Energy Technology Data Exchange (ETDEWEB)

    Suhariyono, Gatot [National Atomic Energy Agency, Jakarta (Indonesia)

    1997-06-01

    National Atomic Energy Agency (NAEA) or Badan Tenaga Atom Nasional (BATAN) is a non departmental governmental agency, headed by a Director General who is directly responsible to the President. Center for Standardization and Radiation Safety Research (CSRSR) is one of the research centers within the deputy for the assessment of nuclear science and technology of the NAEA. The main task of the CSRSR is to implement research and development program, development and services in the field of radiation safety, standardization, dosimetry, radiation health as well as the application of nuclear techniques in medicine, according to the policy confirmed by the director general of BATAN. Task of radiation protection division is to set up programs and to develop radiation protection, personal monitoring system and radiation level of the working areas and their surroundings as well as dose limitation system, to carry out technical up grading of radiation protection officials skill and to help coping with radiation accident. The key factor on contamination monitoring is to reduce human error and mechanical failures. These problems can be achieved to the highest degree by developing knowledge and skill of staffs via trainings or courses on contamination and decontamination, so that they are hoped to become trained and qualified staffs. (G.K.)

  11. 32 CFR 621.1 - Loan of Army/Defense Logistics Agency (DLA) owned property for use at national and State...

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Loan of Army/Defense Logistics Agency (DLA) owned property for use at national and State conventions. 621.1 Section 621.1 National Defense Department of... of Army/Defense Logistics Agency (DLA) owned property for use at national and State conventions. (a...

  12. Innovation – a national priority, supported by the regional development agencies

    Directory of Open Access Journals (Sweden)

    Elena ENACHE

    2013-09-01

    Full Text Available The European Union is interested in the overall performance of the group of 27, and in the national contributions in innovation. The target is to create an „Innovation Union” which aims to provide to entrepreneurs the necessary support to transform innovative ideas into products and services because it has been found that the rate is inefficient to reduce the gap between Europe and its main competitors. The competition with the emerging countries cannot also be won without carrying out the provisions of the Europe 2020 Strategy. This paper addresses the Romanian vision on innovation supported by the Regional Development Agencies whose experience can be considered best-practice model.

  13. Microarray analysis of gene expression in disk abalone Haliotis discus discus after bacterial challenge.

    Science.gov (United States)

    De Zoysa, Mahanama; Nikapitiya, Chamilani; Oh, Chulhong; Lee, Youngdeuk; Whang, Ilson; Lee, Jae-Seong; Choi, Cheol Young; Lee, Jehee

    2011-02-01

    In this study, we investigated the gene expression profiling of disk abalone, Haliotis discus discus challenged by a mixture of three pathogenic bacteria Vibrio alginolyticus, Vibrio parahemolyticus, and Listeria monocytogenes using a cDNA microarray. Upon bacteria challenge, 68 (1.6%) and 112 (2.7%) gene transcripts changed their expression levels ≥2 or ≤2 -fold in gills and digestive tract, respectively. There were 46 tissue-specific transcripts that up-regulated specifically in the digestive tract. In contrast, only 13 transcripts showed gill-specific up-regulation. Quantitative real-time PCR was performed to verify microarray data and results revealed that candidate genes namely Krüppell-like factor (KLF), lachesin, muscle lim protein, thioredoxin-2 (TRx-2), nuclear factor interleukin 3 (NFIL-3) and abalone protein 38 were up-regulated. Also, our results further indicated that bacteria challenge may activate the transcription factors or their activators (Krüppell-like factor, inhibitor of NF-κB or Ik-B), inflammatory cytokines (IL-3 regulated protein, allograft inflammatory factor), other cytokines (IFN-44-like protein, SOCS-2), antioxidant enzymes (glutathione-S-transferase, thioredoxin-2 and thioredoxin peroxidase), and apoptosis-related proteins (TNF-α, archeron) in abalone. The identification of immune and stress response genes and their expression profiles in this microarray will permit detailed investigation of the stress and immune responses of abalone genes. Copyright © 2010 Elsevier Ltd. All rights reserved.

  14. Genome Sequence ofArcobactersp. Strain LA11, Isolated from the AbaloneHaliotis discus.

    Science.gov (United States)

    Mizutani, Yukino; Tanaka, Reiji

    2017-03-16

    Arcobacter sp. strain LA11 was isolated from the gut of the abalone Haliotis discus Here, we present the annotation and analysis of the draft genome of this strain, which is involved in nitrogen metabolism. Copyright © 2017 Mizutani and Tanaka.

  15. Más sobre Abalone y algo sobre tuercas: los tetrahexos

    OpenAIRE

    Rupérez, José Antonio; García, Manuel

    2012-01-01

    Comentamos los problemas planteados en anterior artículo sobre jugadas del ABALONE, describiéndolo de nuevo y presentamos el puzle de los Polihexos, fácil de construir y entretenido de resolver; útil para plantear ejercicios de combinatoria y simetrías.

  16. The Agency's Annual Report to the General Assembly of the United Nations for the Year 1968-69. Explanatory Note

    International Nuclear Information System (INIS)

    1969-01-01

    By Resolution GC(XIII)/RES/251 the General Conference requested the Board of Governors to arrange for the preparation of a supplement to the Board's annual report to the General Conference for 1968-69 which, together with that report, shall constitute the Agency's report to the General Assembly of the United Nations for that year. The present document contains the supplement, which deals briefly with some developments in the Agency's work during the period 1 July to 1 October 1969.

  17. Genome sequence of pacific abalone (Haliotis discus hannai): the first draft genome in family Haliotidae.

    Science.gov (United States)

    Nam, Bo-Hye; Kwak, Woori; Kim, Young-Ok; Kim, Dong-Gyun; Kong, Hee Jeong; Kim, Woo-Jin; Kang, Jeong-Ha; Park, Jung Youn; An, Cheul Min; Moon, Ji-Young; Park, Choul Ji; Yu, Jae Woong; Yoon, Joon; Seo, Minseok; Kim, Kwondo; Kim, Duk Kyung; Lee, SaetByeol; Sung, Samsun; Lee, Chul; Shin, Younhee; Jung, Myunghee; Kang, Byeong-Chul; Shin, Ga-Hee; Ka, Sojeong; Caetano-Anolles, Kelsey; Cho, Seoae; Kim, Heebal

    2017-05-01

    Abalones are large marine snails in the family Haliotidae and the genus Haliotis belonging to the class Gastropoda of the phylum Mollusca. The family Haliotidae contains only one genus, Haliotis, and this single genus is known to contain several species of abalone. With 18 additional subspecies, the most comprehensive treatment of Haliotidae considers 56 species valid [ 1 ]. Abalone is an economically important fishery and aquaculture animal that is considered a highly prized seafood delicacy. The total global supply of abalone has increased 5-fold since the 1970s and farm production increased explosively from 50 mt to 103 464 mt in the past 40 years. Additionally, researchers have recently focused on abalone given their reported tumor suppression effect. However, despite the valuable features of this marine animal, no genomic information is available for the Haliotidae family and related research is still limited. To construct the H . discus hannai genome, a total of 580-G base pairs using Illumina and Pacbio platforms were generated with 322-fold coverage based on the 1.8-Gb estimated genome size of H . discus hannai using flow cytometry. The final genome assembly consisted of 1.86 Gb with 35 450 scaffolds (>2 kb). GC content level was 40.51%, and the N50 length of assembled scaffolds was 211 kb. We identified 29 449 genes using Evidence Modeler based on the gene information from ab initio prediction, protein homology with known genes, and transcriptome evidence of RNA-seq. Here we present the first Haliotidae genome, H . discus hannai , with sequencing data, assembly, and gene annotation information. This will be helpful for resolving the lack of genomic information in the Haliotidae family as well as providing more opportunities for understanding gastropod evolution. © The Authors 2017. Published by Oxford University Press.

  18. Molecular identification of disk abalone (Haliotis discus discus) tetraspanin 33 and CD63: Insights into potent players in the disk abalone host defense system.

    Science.gov (United States)

    Priyathilaka, Thanthrige Thiunuwan; Bathige, S D N K; Herath, H M L P B; Lee, Sukkyoung; Lee, Jehee

    2017-10-01

    Tetraspanins are a superfamily of transmembrane proteins involved in a diverse range of physiological processes including differentiation, adhesion, signal transduction, cell motility, and immune responses. In the present study, two tetraspanins, CD63 and tetraspanin 33 (TSPAN33) from disk abalone (AbCD63 and AbTSPAN33), were identified and characterized at the molecular level. The coding sequences for AbCD63 and AbTSPAN33 encoded polypeptides of 234 and 290 amino acids (aa) with predicted molecular mass of 25.3 and 32.5 kDa, respectively. The deduced AbCD63 and AbTSPAN33 protein sequences were also predicted to have a typical tetraspanin domain architecture, including four transmembrane domains (TM), short N- and C- terminal regions, a short intracellular loop, as well as a large and small extracellular loop. A characteristic CCG motif and cysteine residues, which are highly conserved across CD63 and TSPAN33 proteins of different species, were present in the large extracellular loop of both abalone tetraspanins. Phylogenetic analysis revealed that the AbCD63 and AbTSPAN33 clustered in the invertebrate subclade of tetraspanins, thus exhibiting a close relationship with tetraspanins of other mollusks. The AbCD63 and AbTSPAN33 mRNA transcripts were detected at early embryonic development stages of disk abalone with significantly higher amounts at the trochophore stage, suggesting the involvement of these proteins in embryonic development. Both AbCD63 and AbTSPAN33 were ubiquitously expressed in all the tissues of unchallenged abalones analyzed, with the highest expression levels found in hemocytes. Moreover, significant induction of AbCD63 and AbTSPAN33 mRNA expression was observed in immunologically important tissues, such as hemocytes and gills, upon stimulation with live bacteria (Vibrio parahaemolyticus and Listeria monocytogenes), virus (viral hemorrhagic septicemia virus), and two potent immune stimulators [polyinosinic:polycytidylic acid (poly I:C) and

  19. ANDRA - National Radioactive Waste Management Agency. Activity report 2006. Management report - Financial statements 2006

    International Nuclear Information System (INIS)

    2007-06-01

    Created in 1979 within the CEA, the National Radioactive Waste Management Agency (ANDRA) was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied; - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories. This mission includes as well a public service mission in terms of i) collection of waste of the 'small-scale nuclear activities' producers or owners (including the so-called 'household' radioactive waste, i.e. waste owned by private individuals) and ii) clean-up and rehabilitation of orphan polluted sites; - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This mission includes as well an active policy of dialogue with stakeholders both at national and local level. This document is the activity report with the management and financial statements report of the Andra for the year 2006

  20. ANDRA - National Radioactive Waste Management Agency. Activity report 2016. Financial report 2016

    International Nuclear Information System (INIS)

    2017-01-01

    Created in 1979 within the CEA, the National Radioactive Waste Management Agency (ANDRA) was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied; - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories. This mission includes as well a public service mission in terms of i) collection of waste of the 'small-scale nuclear activities' producers or owners (including the so-called 'household' radioactive waste, i.e. waste owned by private individuals) and ii) clean-up and rehabilitation of orphan polluted sites; - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This mission includes as well an active policy of dialogue with stakeholders both at national and local level. This document is the activity and financial report of the Andra for the year 2016

  1. ANDRA - National Radioactive Waste Management Agency. 2014 Activity report - Responsibility in action. Financial report 2014

    International Nuclear Information System (INIS)

    2015-01-01

    Created in 1979 within the CEA, the National Radioactive Waste Management Agency (ANDRA) was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied; - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories. This mission includes as well a public service mission in terms of i) collection of waste of the 'small-scale nuclear activities' producers or owners (including the so-called 'household' radioactive waste, i.e. waste owned by private individuals) and ii) clean-up and rehabilitation of orphan polluted sites; - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This mission includes as well an active policy of dialogue with stakeholders both at national and local level. This document is the activity and financial report of the Andra for the year 2014

  2. ANDRA - National Radioactive Waste Management Agency. Activity report and sustainable development 2013. Financial report 2013

    International Nuclear Information System (INIS)

    2014-01-01

    Created in 1979 within the CEA, the National Radioactive Waste Management Agency (ANDRA) was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied; - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories. This mission includes as well a public service mission in terms of i) collection of waste of the 'small-scale nuclear activities' producers or owners (including the so-called 'household' radioactive waste, i.e. waste owned by private individuals) and ii) clean-up and rehabilitation of orphan polluted sites; - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This mission includes as well an active policy of dialogue with stakeholders both at national and local level. This document is the activity and Sustainable Development Report, with the financial report, of the Andra for the year 2013

  3. ANDRA - National Radioactive Waste Management Agency. Activity report 2015. Financial report 2015

    International Nuclear Information System (INIS)

    2016-01-01

    Created in 1979 within the CEA, the National Radioactive Waste Management Agency (ANDRA) was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied; - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories. This mission includes as well a public service mission in terms of i) collection of waste of the 'small-scale nuclear activities' producers or owners (including the so-called 'household' radioactive waste, i.e. waste owned by private individuals) and ii) clean-up and rehabilitation of orphan polluted sites; - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This mission includes as well an active policy of dialogue with stakeholders both at national and local level. This document is the activity and financial report of the Andra for the year 2015

  4. 76 FR 24476 - Agency Information Collection Activities; Proposed Collection; Comment Request; National Volatile...

    Science.gov (United States)

    2011-05-02

    ... are manufacturers, distributors, and importers of aerosol coatings. These affected entities fall within the North American Industry Classification System (NAICS) Code 32551, ``Paint and Coating... Aerosol Coatings AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In compliance...

  5. Insulin, hospitals and harm: a review of patient safety incidents reported to the National Patient Safety Agency.

    Science.gov (United States)

    Cousins, David; Rosario, Catherine; Scarpello, John

    2011-02-01

    Patient safety incidents involving insulin are frequent and cause considerable distress to people with diabetes and anxieties to their families and carers. This article describes an analysis of the National Reporting and Learning System database of patient safety incidents concerning insulin reported from NHS providers in England and Wales over six years. The main causes are discussed and the ongoing developments by the National Patient Safety Agency and partner organisations to reduce insulin errors are described.

  6. Agency and Resilience: Teachings of Pikangikum First Nation Elders, Northwestern Ontario

    Directory of Open Access Journals (Sweden)

    Andrew M. Miller

    2013-09-01

    Full Text Available Although scholars of social-ecological resilience propose unity between humans and the natural world, much of this work remains based on Cartesian division of mind and body that denies it. We present an example of a unified system of resilience thinking shared with us by Anishinaabe (Ojibway elders of Pikangikum First Nation, northwestern Ontario. The elders' views of boreal forest disturbance and renewal are distinct from western scientific approaches in their recognition of agency, the ability to individually express free will in nonhuman beings including animals, plants, rocks, and forest fire within their landscape. Pikangikum elders perceive that, if relationships based on respect, reciprocity, and noninterference are maintained with other agents, renewal will continue. The proposition of living landscapes composed of diverse nonhuman agents poses challenges to collaboration with western worldviews, which view nature largely as mechanistic and without moral standing. We suggest that a greater attention to nonwestern ontologies can contribute to productive cross-cultural partnerships directed toward fostering resilience.

  7. EMPLOYEE PROMOTION PLANNING IN ANALYTICAL HIERARCHY PROCESS PERSPECTIVE: STUDY ON NATIONAL PUBLIC PROCUREMENT AGENCY

    Directory of Open Access Journals (Sweden)

    Ayuningtyas A.K.

    2017-10-01

    Full Text Available The promotion process is part of the career development conducted by Civil State Apparatus Employee (Pegawai Aparatur Sipil Negara which should be implemented by applying merit system. Employee-related strategic decision making has not applied merit system as mandated in applied laws. It occurred due to Public Service Appointment Board (Badan Pertimbangan Jabatan dan Kepangkatan not possessing assessment model and criteria which could be used to support promotion process implementation in the appropriate structural position based on employee competence and performance. This study aims to describe and analyze assessment criteria and subcriteria required to be considered in State Civil Servant Officers promotion planning by applying Analytical Hierarchy Process (AHP method in National Public Procurement Agency (Lembaga Kebijakan Pengadaan Barang/Jasa Pemerintah. This study uses the explanative quantitative univariate method. Data collection technique used questionnaire instrument. Analytical tool used was AHP. Research result exhibits that ASN employee promotion planning using assessment model is described as follows: Employee Performance Assessment consist of Employee Work Performance element with three criteria and Employee Work Behavior with twenty-three criteria; and Evaluation of Employee Promotion Implementation with eleven criteria. Through the use of AHP methods employee, promotion planning could be utilized as a tool for Baperjakat to produce employee decisions that will be promoted objectively and effectively.

  8. [The senses of sanitary safety in the discourse of the National Health Surveillance Agency].

    Science.gov (United States)

    Barbosa, Ana de Oliveira; Costa, Ediná Alves

    2010-11-01

    The term sanitary safety (SS) appeared in the international debate mainly due to the emerging sanitary crisis, although its meaning has remained obscure. This paper aims to analyze the concept of SS brought into the Brazilian sanitary surveillance upon the creation of the National Health Surveillance Agency. An exploratory case study was undertaken with technical data analysis and semi-structured interviews with informants who had taken part in the process of formulating the body's institutional design. The following categories were analyzed: incorporation of the SS term into the institutional mission, the SS concept and SS mechanisms. The SS concept was analyzed in both institutional and technical discursive dimensions. The former elicits the sense of strategy, a reliable relationship and legitimacy whereas the latter shows the sense of an acceptable risk-benefit relationship from the perspective of individual and collective health protection and promotion. The SS concept was found to encompass health-related products, technologies and services, especially those designed for medical diagnosis and treatment, but environmental issues received little mention. The scope of the SS concept was shown to be widening to include the surveillance of hospital infection, drugs and blood.

  9. 75 FR 60762 - Board of Scientific Counselors (BSC), National Center for Environmental Health/Agency for Toxic...

    Science.gov (United States)

    2010-10-01

    ... Scientific Counselors (BSC), National Center for Environmental Health/Agency for Toxic Substances and Disease... Meeting on October 21-22, 2010 will include presentations from the Division of Environmental Hazards and.... October 21, 2010. Contact Person for More Information: Sandra Malcom, Committee Management Specialist...

  10. 75 FR 25870 - Board of Scientific Counselors (BSC), National Center for Environmental Health/Agency for Toxic...

    Science.gov (United States)

    2010-05-10

    ... Scientific Counselors (BSC), National Center for Environmental Health/Agency for Toxic Substances and Disease... Emergency and Environmental Health Services (EHHE); an overview of the Division of Environmental Hazards and.... Contact Person for More Information: Sandra Malcom, Committee Management Specialist, NCEH/ATSDR, 4770...

  11. KARAKTERISASI DAN EVALUASI POPULASI ABALON Haliotis squamata SECARA MOLEKULER, MORFOMETRIK, DAN BIOLOGI

    Directory of Open Access Journals (Sweden)

    Gusti Ngurah Permana

    2017-10-01

    Full Text Available Abalon merupakan salah satu komoditas penting gastropoda laut. Tingginya permintaan abalon ini mengakibatkan menipisnya stok di alam. Oleh karena itu, upaya keberhasilan budidaya abalon perlu didukung oleh jenis unggul. Indikasi awal suatu jenis unggul dapat dilakukan dengan menganalisis potensi genetik yang dimiliki. Penelitian ini dilakukan dengan analisis gen 16S rRNA, karakter morfolologi, dan biologi dianalisis secara deskriptif dengan metode kajian pustaka. Hasil yang diperoleh menunjukkan keragaman inter populasi Haliotis squamata mendeteksi adanya tujuh haplotipe yang terbagi dalam dua kelompok. Penyertaan H. diversicolor sebagai outgroup dalam pengujian memperlihatkan bahwa populasi H. squamata dari Pulau Bali dan beberapa lokasi di Pulau Jawa berada dalam satu kelompok yang terpisah dengan outgroup. Hasil ini kongruen dengan analisis morfometrik terdapat perkembangan pertumbuhan cangkang yang asimetri pada populasi Banten. Pertumbuhan asimetri merupakan indikasi spesifik untuk populasi Banten atau merupakan gejala abnormalitas yang dapat diakibatkan oleh faktor penurunan kualitas genetik atau lingkungan. Karakter biologi terlihat proporsi daging dan gonad berbeda pada populasi Banten dengan indikasi adanya pertumbuhan asimetri. Rasio gonad dan daging populasi Banyuwangi berbeda nyata (P<0,05 dengan populasi lainnya. Abalone is arguably one of the highly valued and sought-after marine gastropods. However, the over-exploitation of this species has exhausted its wild stock. To overcome this challenge, the culture technique and management of this species must be established and continually improved. One of the ways is through producing superior broodstocks. An initial assessment of a genetically superior broodstock can be done using the potential genetic analysis. This recent research employed the analysis to study the species’ 16S rRNA gene. To complement the study, the morphometric and biological characteristics of the species were

  12. Report of the International Atomic Energy Agency to the General Assembly of the United Nations

    International Nuclear Information System (INIS)

    1959-10-01

    The report is submitted in accordance with Article III.B.4 of the Statute and Article III of the Relationship Agreement between the two organizations and describes the important developments in the work of the Agency from 1 July 1950 to 30 June 1959. It is thus the first to cover a full year of the activities of the Agency. The important developments in the Agency's work since the report was prepared are covered briefly in this preface. The period covered is characterized by the fact that Member States began to make substantial requests to the Agency for assistance, which the Agency was able to meet. Furthermore, the Agency began to carry out its regulatory tasks, organized its first meeting, conferences and symposia, started its own research and greatly expanded the collection and publication of technical information

  13. An Assessment of the Efficiency of Government Regulatory Agencies in Nigeria. Case of the National Agency for Food and Drugs Administration and Control

    Directory of Open Access Journals (Sweden)

    Aiwanehi Barbara Ofuani

    2015-09-01

    Full Text Available This study examines Business, Government and Society interrelationships. It eventually narrowed down to assessing the efficiency of government regulatory agencies, in fulfilling the role of government in protecting consumers from unscrupulous practices of businesses. The National Agency for Food and Drugs Administration and Control (NAFDAC was chosen for the study. Since the expectations of the consumers are paramount here, the stakeholder approach method was used for assessing the efficiency of NAFDAC. Literature and previous empirical studies on the topic were examined. For representativeness, data was collected utilizing the survey research design through Questionnaire distributed to 200 respondents in some areas of Lagos Mainland in Lagos state, using the convenience sampling method. 187 copies of the questionnaire representing 93.5% were returned and usable. Descriptive statistics was used to analyze the responses to questions regarding the efficiency of NAFDAC and a hypothesis tested using a one-sample T-test. The findings ran contrary to results from some previous studies. Instead, consumer awareness of the existence of NAFDAC as a regulatory agency and its functions were established, along with a high rate of consumer education. The assessment of its efficiency also showed a high rating. Recommendations were made that the study be replicated in other states of Nigeria and further studies carried out to evaluate its efficiency under previous and current directors for improvement purposes.

  14. The accountability of the brazilian regulatory agencies: the experience of the National Petroleum Agency; O controle externo das agencias reguladoras: o caso da Agencia Nacional do Petroleo

    Energy Technology Data Exchange (ETDEWEB)

    Pinto Junior, Helder Queiroz; Borges, Heloisa Lopes [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Inst. de Economia. Grupo de Economia da Energia

    2004-07-01

    During the reform process for which passed the Brazilian Oil and Gas Industry, the academic debate was centered mostly in the sectorial restructuring process, in the contract designs and regulatory environment for the industries in change, particularly the desired attributes of its institutions. The debate tends, in the present, to converge towards the existence of different possible combinations between market structures and institutional structures (the regulators among them) that would lead to a desirable result. Thus, the various characteristics and configurations, originally appointed as necessary conditions for the success of any reform, are not dealt with such great deference anymore. The hypothesis that the existence of a independent regulator is a determinant choice for the success of structural and institutional reforms was relaxed as general rule, but there are still strong economic reasons to justify the option, adopted in Brazil. The creation of the Oil National Agency (ANP), the Brazilian regulator for the Oil and Gas Industry is a recent phenomenon. And few studies specifically approach the issue of its accountability, institutional role that in Brazil is delegated mostly, but not exclusively, to the National Court of Accounts (Tribunal de Contas da Uniao). Therefore, the objective of this work will be to discuss the different possibilities of accountability over the ANP, evaluating the paper and the functions of the TCU and the forms of external control on the Agency, pointing out the possibilities, the impediments and the challenges, as well as the economic consequences to the Natural Gas Industry of the current configuration. (author)

  15. Gene expression profiling in respond to TBT exposure in small abalone Haliotis diversicolor.

    Science.gov (United States)

    Jia, Xiwei; Zou, Zhihua; Wang, Guodong; Wang, Shuhong; Wang, Yilei; Zhang, Ziping

    2011-10-01

    In this study, we investigated the gene expression profiling of small abalone, Haliotis diversicolor by tributyltin (TBT) exposure using a cDNA microarray containing 2473 unique transcripts. Totally, 107 up-regulated genes and 41 down-regulated genes were found. For further investigation of candidate genes from microarray data and EST analysis, quantitative real-time PCR was performed at 6 h, 24 h, 48 h, 96 h and 192 h TBT exposure. 26 genes were found to be significantly differentially expressed in different time course, 3 of them were unknown. Some gene homologues like cellulose, endo-beta-1,4-glucanase, ferritin subunit 1 and thiolester containing protein II CG7052-PB might be the good biomarker candidate for TBT monitor. The identification of stress response genes and their expression profiles will permit detailed investigation of the defense responses of small abalone genes. Published by Elsevier Ltd.

  16. Immune priming and portal of entry effectors improve response to vibrio infection in a resistant population of the European abalone.

    Science.gov (United States)

    Dubief, Bruno; Nunes, Flavia L D; Basuyaux, Olivier; Paillard, Christine

    2017-01-01

    Since 1997, populations of the European abalone Haliotis tuberculata suffer mass mortalities attributed to the bacterium Vibrio harveyi. These mortalities occur at the spawning season, when the abalone immune system is depressed, and when temperatures exceed 17 °C, leading to favorable conditions for V. harveyi proliferation. In order to identify mechanisms of disease resistance, experimental successive infections were carried out on two geographically distinct Brittany populations: one that has suffered recurrent mortalities (Saint-Malo) and one that has not been impacted by the disease (Molène). Furthermore, abalone surviving these two successive bacterial challenges and uninfected abalone were used for several post-infection analyses. The Saint-Malo population was found to be resistant to V. harveyi infection, with a survival rate of 95% compared to 51% for Molène. While in vitro quantification of phagocytosis by flow cytometry showed strong inhibition following the first infection, no inhibition of phagocytosis was observed following the second infection for Saint-Malo, suggesting an immune priming effect. Moreover, assays of phagocytosis of GFP-labelled V. harveyi performed two months post-infection show an inhibition of phagocytosis by extracellular products of V. harveyi for uninfected abalone, while no effect was observed for previously infected abalone from Saint-Malo, suggesting that the effects of immune priming may last upwards of two months. Detection of V. harveyi by qPCR showed that a significantly greater number of abalone from the susceptible population were positive for V. harveyi in the gills, indicating that portal of entry effectors may play a role in resistance to the disease. Collectively, these results suggest a potential synergistic effect of gills and hemolymph in the resistance of H. tuberculata against V. harveyi with an important involvement of the gills, the portal of entry of the bacteria. Copyright © 2016 Elsevier Ltd

  17. US Environmental Protection Agency National Coastal Assessment for American Samoa 2004: water quality, sediment grain, and chemistry data (NODC Accession 0000455)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In 2004, the Environmental Protection Agency (EPA) Environmental Monitoring and Assessment Program (EMAP) National Coastal Assessment (NCA), coordinated through the...

  18. Availability of phosphorus from selected inorganic phosphate to juvenile abalone, Haliotis discus hannai ino.

    Science.gov (United States)

    Tan, Bei-Ping; Mai, Kang-Sen; Xu, Wei

    2002-06-01

    The availability of phosphorus to juvenile abalone, Haliotis discus hannai from primary, secondary and tertiary calcium phosphate, primary sodium or potassium phosphate separately or in combination was determined in a 120-day feeding trial. Seven semi-purified diets were formulated to contain relatively constant dietary phosphorus, ranging from 0.78% 0.82%. The concentrations of dietary phosphorus were presumed to be slightly below the requirement for abalone. A brown alga, Laminaria japonica, was used as a control diet. Abalone juveniles of silimar size (average weight 1.18 g; average shell length 18.74 mm) were distributed in a single-pass, flow-through system using a completely randomized design with eight treatments and three replicates each treatment. The survival ranged from 71.1% to 81.1%, and was not significantly (P>0.05) related to dietary treatment. However, the weight gain rate (41.72% 65.02%), daily increment in shell length (36.87 55.07 μm) and muscle RNA-DNA ratio (3.44 4.69) were significantly (Pdietary treatment. Soft body alkaline phosphatase activity (10.9 19.8 U/g wet tissue) and carcass levels of lipid (7.71% 9.33%) and protein (46.68% 49.35%) were significantly (PDietary treatment had significant effect (Pdietary treatments. The results indicated that among these inorganic compounds, primary calcium, potassium and sodium phosphates separately or in combination could be utilized effectively by juvenile abalone as dietary phosphorus sources (availability ranging from 87% 97%). However, secondary and tertiary calcium phosphates were found to be low in availability, the values being 45% and 77%, repectively.

  19. Abalone, Haliotis mariae (Wood, 1828, Hatchery and Seed Production Trials in Oman

    Directory of Open Access Journals (Sweden)

    Khalfan M. Al-Rashdi

    2008-01-01

    Full Text Available Hatchery and seed production trials for the Omani endemic abalone Haliotis mariae were carried out at the land-based Mirbat Abalone Seed Production Station in Oman between 1999 and 2000. The methods developed for broodstock conditioning, induction of spawning and fertilization, larval settlement, and the handling of small juveniles are shown. Abalone collected in the post-monsoon period and held for 2 months matured faster than those collected before the monsoon and held for 6 months. Spawning induction of males and females had 63% and 11% success rates respectively, and the morphology of early larval stages is shown. Survival rates of veliger larvae introduced to settlement plates ranged from 35.9% to 73.7%, but the survival of post-larvae was low at 0.1% to 3.6%. The high mortality rate was attributed to invasions of filamentous green- and coralline algae on settlement plates and occurrence of low quantity of diatoms as food. Juveniles reacted best to 2% ethanol as anaesthetic, dropping off culture plates within 4 min and recovering within 17 min. Cultured abalone reached an average shell length of 52.9 mm over 13 months, which translates to an increment of 4.1 mm.mon-1. The overall conclusion of these preliminary research trials confirms  that H. mariae can be cultured successfully in Oman. Further studies on the standardization of the techniques would help in stock enhancement programmes and commercial farming.

  20. Two ferritin subunits from disk abalone (Haliotis discus discus): cloning, characterization and expression analysis.

    Science.gov (United States)

    De Zoysa, Mahanama; Lee, Jehee

    2007-09-01

    Ferritin plays a key role in cellular iron metabolism, which includes iron storage and detoxification. From disk abalone, Haliotis discus discus, the cDNA that encodes the two ferritin subunits abalone ferritin subunit 1 (Abf1) and abalone ferritin subunit 2 (Abf2) were cloned. The complete cDNA coding sequences for Abf1 and Abf2 contained 621 and 549 bp, encoding for 207 and 183 amino acid residues, respectively. The H. discus discus Abf2 subunit contained a highly conserved motif for the ferroxidase center, which consists of seven residues of a typical vertebrate heavy-chain ferritin with a typical stem-loop structure. Abf2 mRNA contains a 27 bp iron-responsive element (IRE) in the 5'UTR position. This IRE exhibited 96% similarity with pearl and Pacific oyster and 67% similarity with human H type IREs. However, the Abf1 subunit had neither ferroxidase center residues nor the IRE motif sequence; instead, it contained iron-binding region signature 2 (IBRS) residues. Recombinant Abf1 and Abf2 proteins were purified and the respective sizes were about 24 and 21 kDa. Abf1 and Abf2 exhibited iron-chelating activity 44.2% and 22.0%, respectively, at protein concentration of 6 microg/ml. Analysis of tissue-specific expression by RT-PCR revealed that Abf1 and Abf2 ferritin mRNAs were expressed in various abalone tissues, such as gill, mantle, gonad, foot and digestive tract in a wide distribution profile, but Abf2 expression was more prominent than Abf1.

  1. Evolution of large body size in abalones (Haliotis): Patterns and implications

    Science.gov (United States)

    Estes, J.A.; Lindberg, D.R.; Wray, C.

    2005-01-01

    Kelps and other fleshy macroalgae - dominant reef-inhabiting organisms in cool - seasmay have radiated extensively following late Cenozoic polar cooling, thus triggering a chain of evolutionary change in the trophic ecology of nearshore temperate ecosystems. We explore this hypothesis through an analysis of body size in the abalones (Gastropoda; Haliotidae), a widely distributed group in modern oceans that displays a broad range of body sizes and contains fossil representatives from the late Cretaceous (60-75 Ma). Geographic analysis of maximum shell length in living abalones showed that small-bodied species, while most common in the Tropics, have a cosmopolitan distribution, whereas large-bodied species occur exclusively in cold-water ecosystems dominated by kelps and other macroalgae. The phylogeography of body size evolution in extant abalones was assessed by constructing a molecular phylogeny in a mix of large and small species obtained from different regions of the world. This analysis demonstrates that small body size is the plesiomorphic state and largeness has likely arisen at least twice. Finally, we compiled data on shell length from the fossil record to determine how (slowly or suddenly) and when large body size arose in the abalones. These data indicate that large body size appears suddenly at the Miocene/Pliocene boundary. Our findings support the view that fleshy-algal dominated ecosystems radiated rapidly in the coastal oceans with the onset of the most recent glacial age. We conclude with a discussion of the broader implications of this change. ?? 2005 The Paleontological Society. All rights reserved.

  2. Matrix metalloproteinases (MMPs) inhibitory effects of an octameric oligopeptide isolated from abalone Haliotis discus hannai.

    Science.gov (United States)

    Nguyen, Van-Tinh; Qian, Zhong-Ji; Ryu, Bomi; Kim, Kil-Nam; Kim, Daekyung; Kim, Young-Mog; Jeon, You-Jin; Park, Won Sun; Choi, Il-Whan; Kim, Geun Hyung; Je, Jae-Young; Jung, Won-Kyo

    2013-11-01

    Abalone (Haliotis discus hannai) is a marine gastropod, and an important fishery and food industrial resource that is massively maricultured in Asia, Africa, Australia and America. However, its health benefits have rarely been studied for nutraceutical and pharmaceutical application. In this study, the purified abalone oligopeptide (AOP) with anti-matrix metalloproteinases (anti-MMPs) effects was isolated from the digests of abalone intestine using recycle HPLC with a JAI W253 column and an OHpak SB-803 HQ column. The AOP was identified as Ala-Glu-Leu-Pro-Ser-Leu-Pro-Gly (MW=782.4 Da) with a de novo peptide sequencing technique using a tandem mass spectrometer. The AOP exhibited a specific inhibitory effect against MMP-2/-9 activity and attenuated protein expression of p50 and p65 in the human fibrosarcoma (HT1080) cells, dose-dependently. The results presented illustrate that the AOP could inhibit MMP-2/-9 expression in HT1080 cells via the nuclear factor-kappaB (NF-κB)-mediated pathway. This data suggest that the AOP from H. discus hannai intestine may possess therapeutic and preventive potential for the treatment of MMPs-related disorders such as angiogenesis and cardiovascular diseases. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Black, green, and red abalones. Species profiles: life histories and environmental requirements of coastal fishes and invertebrates (Pacific Southwest. )

    Energy Technology Data Exchange (ETDEWEB)

    Ault, J.S.

    1985-03-01

    Black, green, and red abalones (Haliotis cracherodii, H. fulgens, and H. rufescens, respectivley) are of commercial and ecological importance and are distributed widely along the California coast. The abalones are morphologically similar; species are distinguished by particular shell sculpture, color, and body characteristics. Their latitudinal and bathymetric distribution is stratified and most closely related to temperature. Small juveniles eat mainly microflora; adults eat primarily drift macro-algae, preferring specific brown or red algae, when available. Spawning occurs during summer; gonad ripening depends on food quality and quantity and water temperature. Larvae are lecithotrophic and remain planktonic for periods of 5 to 14 days after hatching; settling is substrate specific. Postlarvae and adults require hard substrate for attachment. Juveniles are cryptic, adults usually more exposed. Growth rates are similar, although maximum size varies with species. Increases in shell length and body weight correlate positively with food abundance and temperature. Below depths of 6 m, sea urchins are major competitors for food and space. Predation by invertebrates is low. Decreased abalone production from central California is associated with range expansion and increased predation by sea otters, the major source of abalone mortality. General declines in California landings are due to mortality from improper picking and replacement, habitat degradation, and perhaps overfishing. Commercial and sport diving efforts have increased sharply, whereas annual landings of abalones declined from 1965 to 1982.

  4. Alternative Splicing Profile and Sex-Preferential Gene Expression in the Female and Male Pacific Abalone Haliotis discus hannai.

    Science.gov (United States)

    Kim, Mi Ae; Rhee, Jae-Sung; Kim, Tae Ha; Lee, Jung Sick; Choi, Ah-Young; Choi, Beom-Soon; Choi, Ik-Young; Sohn, Young Chang

    2017-03-09

    In order to characterize the female or male transcriptome of the Pacific abalone and further increase genomic resources, we sequenced the mRNA of full-length complementary DNA (cDNA) libraries derived from pooled tissues of female and male Haliotis discus hannai by employing the Iso-Seq protocol of the PacBio RSII platform. We successfully assembled whole full-length cDNA sequences and constructed a transcriptome database that included isoform information. After clustering, a total of 15,110 and 12,145 genes that coded for proteins were identified in female and male abalones, respectively. A total of 13,057 putative orthologs were retained from each transcriptome in abalones. Overall Gene Ontology terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways analyzed in each database showed a similar composition between sexes. In addition, a total of 519 and 391 isoforms were genome-widely identified with at least two isoforms from female and male transcriptome databases. We found that the number of isoforms and their alternatively spliced patterns are variable and sex-dependent. This information represents the first significant contribution to sex-preferential genomic resources of the Pacific abalone. The availability of whole female and male transcriptome database and their isoform information will be useful to improve our understanding of molecular responses and also for the analysis of population dynamics in the Pacific abalone.

  5. Effect of Abalone Hydrolysates Encapsulated by Double Emulsion on the Physicochemical and Sensorial Properties of Fresh Cheese.

    Science.gov (United States)

    Choi, HeeJeong; Kim, Soo-Jin; Lee, Sang-Yoon; Choi, Mi-Jung

    2017-01-01

    The intake of dietary salt through food now exceeds current nutritional recommendations and is thought to have negative effects on human health, such as the increasing prevalence of hypertension. This study was performed to investigate whether W 1 /O/W 2 double emulsions can be used to enhance the saltiness of cheese without increasing the salt content (W 1 is distilled water or 1% abalone hydrolysate, and W 2 is 1% NaCl or 1% abalone hydrolysate + 1% NaCl solution). We also investigated the effect of adding abalone hydrolysate to the double emulsion as a saltiness enhancer. The cheeses were physico-chemically evaluated to determine curd yield, pH value, moisture content, color, texture, salt release rate, and sensory properties. No significant differences were observed in curd yield, pH value, moisture content, lightness, or redness between the cheeses made with and without the double emulsion. However, in the evaluation of salt release rate, fresh cheese made with double emulsion (W 1 = distilled water, W 2 = 1% NaCl + 1% abalone hydrolysate) was detected earlier than the control or the other treatments. In the sensory evaluation, fresh cheese made with the double emulsion showed higher scores for saltiness and overall preference than the control or the other treatments. We concluded that abalone hydrolysate encapsulated in a double emulsion (W 1 is water and W 2 is abalone hydrolysate and NaCl solution) could enhance the saltiness of fresh cheese while maintaining the same salt concentration, without altering its physical properties.

  6. 76 FR 63623 - Board of Scientific Counselors, National Center for Environmental Health/Agency for Toxic...

    Science.gov (United States)

    2011-10-13

    ..., strategies, and priorities in fulfillment of the agency's mission to protect and promote people's health. The...: indoor air pollution and health and lead in Nigeria. Agenda items are subject to change as priorities... Person for More Information: Sandra Malcom, Committee Management Specialist, NCEH/ATSDR, 4770 Buford...

  7. Recreation partnerships on national forests: The influences of institutional commitment and urban proximity on agency capacity

    Science.gov (United States)

    Allie E. McCreary; Erin Seekamp; Lee. Cerveny

    2012-01-01

    This paper presents data from the second phase of a multiphase study being conducted to explore the structure and function of U.S. Forest Service (FS) recreation partnerships. In Phase I, institutional commitment and urban proximity emerged as key indicators of agency capacity to effectively develop and maintain recreation partnerships. In Phase II, multiple case...

  8. 77 FR 63341 - Agency Information Collection Activities; Proposed Collection; Comments Requested: National...

    Science.gov (United States)

    2012-10-16

    ... the proper performance of the functions of the agency, including whether the information will have... purpose of the voluntary NIJ Compliance Testing Program (CTP) is to provide confidence that equipment used for law enforcement and corrections applications meets minimum published performance requirements. One...

  9. Genome Sequences of a Novel Picorna-Like Virus from Pacific Abalone (Haliotis discus hannai) in South Korea.

    Science.gov (United States)

    Kim, Jong-Oh; Lee, Jong Kyu; Seo, Yong Bae; Lim, Han-Kyu; Kim, Gun-Do

    2017-09-07

    We report the draft genome sequences of a novel member of the Picornavirales isolated from Pacific abalone ( Haliotis discus hannai ). The full length of the assembled draft genome sequences, obtained by use of a next-generation sequencing technique, were 8,019 nucleotides, including an RNA-dependent RNA polymerase gene (5,088 nucleotides) and a capsid protein gene (2,553 nucleotides). This genome sequence will be useful for understanding viral disease of Pacific abalone. Copyright © 2017 Kim et al.

  10. 78 FR 76412 - Agency Information Collection (VA National Rehabilitation Special Events, Event Registration...

    Science.gov (United States)

    2013-12-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF VETERANS... Application, VA Form 0924t. e. National Veterans Wheelchair Games Event Application, VA Form 0925b. f. Voluntary Service Application, VA Form 0925d. g. National Veteran Golden Age Games Application, VA Form 0926...

  11. 76 FR 5186 - National Protection and Programs Directorate; Agency Information Collection Activities; Office of...

    Science.gov (United States)

    2011-01-28

    ...) to the Office of Management and Budget (OMB) for review and clearance in accordance with the... public understand the key concepts, are aware of their contribution to achieve a shared national goal... nation's infrastructure; Assist in validating and achieving IP's strategic and mission area objectives...

  12. 77 FR 57154 - Agency Information Collection Activities: Proposed Collection; Comment Request; National Youth...

    Science.gov (United States)

    2012-09-17

    ... Collection Activities: Proposed Collection; Comment Request; National Youth Gang Survey ACTION: 60-Day notice...: Extension of a currently approved collection. 2. Title of the Form/Collection: National Youth Gang Survey. 3... will gather information related to youth and their activities for research and assessment purposes. 5...

  13. Payload operations management of a planned European SL-Mission employing establishments of ESA and national agencies

    Science.gov (United States)

    Joensson, Rolf; Mueller, Karl L.

    1994-01-01

    Spacelab (SL)-missions with Payload Operations (P/L OPS) from Europe involve numerous space agencies, various ground infrastructure systems and national user organizations. An effective management structure must bring together different entities, facilities and people, but at the same time keep interfaces, costs and schedule under strict control. This paper outlines the management concept for P/L OPS of a planned European SL-mission. The proposal draws on the relevant experience in Europe, which was acquired via the ESA/NASA mission SL-1, by the execution of two German SL-missions and by the involvement in, or the support of, several NASA-missions.

  14. Impact assessment of Public Relations in the Fiscal Control Management of the National Agency for Fiscal Administration

    Directory of Open Access Journals (Sweden)

    D.Haranguş

    2013-12-01

    Full Text Available The present study examines the role of public relations as a socio-economic tool of persuasion and educating taxpayers of their civic responsibility to honor fair tax obligations. We propose solutions for improving and restructuring the fiscal control management by diversifying and expanding the range of the instrument constant communication/ public relations and increasing their efficiency in the National Agency for Fiscal Administration, diversifying forms of public communication. The proposed work aims to fill a niche in tax audit work of taxpayers to be felt in practice equitable collection of taxes.

  15. Feasibility study for automating the analytical laboratories of the Chemistry Branch, National Enforcement Investigation Center, Environmental Protection Agency

    International Nuclear Information System (INIS)

    Morris, W.F.; Fisher, E.R.; Barton, G.W. Jr.

    1978-01-01

    The feasibility of automating the analytical laboratories of the Chemistry Branch of the National Enforcement Investigation Center, Environmental Protection Agency, Denver, Colorado, is explored. The goals of the chemistry laboratory are defined, and instrumental methods and other tasks to be automated are described. Five optional automation systems are proposed to meet these goals and the options are evaluated in terms of cost effectiveness and other specified criteria. The instruments to be automated include (1) a Perkin-Elmer AA spectrophotometer 403, (2) Perkin-Elmer AA spectrophotometer 306, (3) Technicon AutoAnalyzer II, (4) Mettler electronic balance, and a (5) Jarrell-Ash ICP emission spectrometer

  16. GROW-OUT OF ABALONE Haliotis squamata IN FLOATING CAGES FED DIFFERENT PROPORTIONS OF SEAWEED AND WITH REDUCTION OF STOCKING DENSITY

    Directory of Open Access Journals (Sweden)

    I Nyoman Adiasmara Giri

    2014-06-01

    Full Text Available Abalone is a herbivore marine animal which feeds on seaweed. Abalone culture has a good prospect in terms of price, market share and simple culture technique. Thus, a study was conducted with the aim of finding out an effective and efficient abalone culture technique in terms of feed use and density. In this study, a 42 cm diameter plastic container with a 22 cm height was used. Three vertically arranged containers were used as the experimental group which were put into a net box and hung onto a raft so that the containers were placed in a 4 m depth below the sea surface. The juvenile of abalones being used came from a hatchery production that has been adapted to cages environment with Gracilaria sp. and Ulva sp. feed. The initial density of abalones was 450 for each container, with the initial weight of 2.6-3.2 g and the 2.5-2.7 cm shell lengths. The abalones were fed with Gracilaria sp. and Ulva sp. seaweeds with different Gracilaria sp./Ulva sp. proportions, i.e. 100/0% (A; 80/20% (B; and 60/40% (C as the treatments. Each treatment consisted of two replications. After three months of rearing period, densities of abalones were reduced to be 190 for each experimental unit. Weight and shell length of abalones were measured every month by measuring 25 abalone samples from each experimental unit. The result of the experiment showed that the increase in the Ulva sp. proportion in the feed increased the growth of abalones and decreased the feed conversion. Feeding with Gracilaria sp./Ulva sp. proportion of 60%/40% allowed the best growth of abalones. The decrease of abalone density in the experimental unit after three months of rearing also produced an increase in their growth.

  17. 76 FR 59379 - Agency Information Collection Activities: Proposed Collection; Comment Request-National Universal...

    Science.gov (United States)

    2011-09-26

    ... Nutrition Service (FNS). FNS provides grant funding and issues regulations which are utilized by WIC State..., Hunger-Free Kids Act of 2010 directs the Secretary of Agriculture to establish a National Universal...

  18. Crisis Response Interoperability System: Enabling Multi-National and Multi-Agency Defence Against Terrorism

    National Research Council Canada - National Science Library

    Roy, Jean; Dessureault, Dany; Letourneau, Francois

    2004-01-01

    We live in an increasingly interconnected, complex and often dangerous world, and recent events have moved the issues of anti- and counter-terrorism, national/public security, and collective emergency...

  19. Contracting seminar - engineering services to federal agencies - of the National Society of Professional Engineers annual meeting

    Energy Technology Data Exchange (ETDEWEB)

    1979-12-01

    The seminar discusses the government-private sector engineering team for accomplishing engineering for the government. The challenge of engineers for the 1980s focuses on energy. Approach in accomplishing engineering is different for different agencies. How the Corps of Engineers, TVA, and DOE team together with the private sector to accomplish engineering is discussed. Representatives from these organizations made presentations, and then principals from three firms discussed how they work as part of the government team and how they manage the work. They discussed the requirements they must meet and the hurdles they must overcome in working for the government. A question-and-answer period followed.

  20. Nearly Half Of All Medicare Hospice Enrollees Received Care From Agencies Owned By Regional Or National Chains

    Science.gov (United States)

    Stevenson, David G.; Dalton, Jesse B.; Grabowski, David C.; Huskamp, Haiden A.

    2016-01-01

    To date, analyses of ownership in the US hospice sector have focused on the growth of for-profit hospice and on aggregate differences in patient populations and service use patterns between for-profit and not-for-profit agencies. Although such comparisons are useful, they do not offer insights about the types of organizations that comprise the hospice sector, including the emergence of multi-agency chains. Using Medicare Cost Reports from 2000 to 2011, we track the evolution of the US hospice industry, not only to describe the market's composition by profit status but also to provide new information about the roles of regional and national chains. Almost half of all Medicare hospice enrollees received these services from a multi-agency chain in 2011. Although a handful of companies play a prominent role, the presence of smaller for-profit and not-for-profit hospice chains also has grown in recent years. By focusing on the role of the diverse organizations that provide hospice care, our analyses can help inform efforts to monitor and assure quality of care, to assess payment adequacy and options for reform, and to facilitate greater transparency and accountability within the hospice marketplace. PMID:25561641

  1. Amplified fragment length polymorphism analysis to assess crossover interference and homozygosity in gynogenetic diploid Pacific abalone (Haliotis discus hannai).

    Science.gov (United States)

    Nie, H-T; Li, Q; Kong, L-F

    2014-06-01

    Recombination analysis in gynogenetic diploids is a powerful tool for assessing the degree of inbreeding, investigating crossover events and understanding chiasma interference during meiosis. To estimate the marker-centromere recombination rate, the inheritance pattern of 654 amplified fragment length polymorphism (AFLP) markers was examined in the 72-h veliger larvae of two meiogynogenetic diploid families in the Pacific abalone (Haliotis discus hannai). The second-division segregation frequency (y) of the AFLP loci ranged from 0.00 to 0.96, with 23.9% of loci showing y-values higher than 0.67, evidencing the existence of interference. The average recombination frequency across the 654 AFLP loci was 0.45, allowing estimation of the fixation index of 0.55, indicating that meiotic gynogenesis could provide an effective means of rapid inbreeding in the Pacific abalone. The AFLP loci have a small proportion (4.4%) of y-values greater than 0.90, suggesting that a relatively low or intermediate degree of chiasma interference occurred in the abalone chromosomes. The information obtained in this study will enhance our understanding of the abalone genome and will be useful for genetic studies in the species. © 2014 Stichting International Foundation for Animal Genetics.

  2. Effect of drying process assisted by high-pressure impregnation on protein quality and digestibility in red abalone (Haliotis rufescens).

    Science.gov (United States)

    Cepero-Betancourt, Yamira; Oliva-Moresco, Patricio; Pasten-Contreras, Alexis; Tabilo-Munizaga, Gipsy; Pérez-Won, Mario; Moreno-Osorio, Luis; Lemus-Mondaca, Roberto

    2017-10-01

    Abalone (Haliotis spp.) is an exotic seafood product recognized as a protein source of high biological value. Traditional methods used to preserve foods such as drying technology can affect their nutritional quality (protein quality and digestibility). A 28-day rat feeding study was conducted to evaluate the effects of the drying process assisted by high-pressure impregnation (HPI) (350, 450, and 500 MPa × 5 min) on chemical proximate and amino acid compositions and nutritional parameters, such as protein efficiency ratio (PER), true digestibility (TD), net protein ratio, and protein digestibility corrected amino acid score (PDCAAS) of dried abalone. The HPI-assisted drying process ensured excellent protein quality based on PER values, regardless of the pressure level. At 350 and 500 MPa, the HPI-assisted drying process had no negative effect on TD and PDCAAS then, based on nutritional parameters analysed, we recommend HPI-assisted drying process at 350 MPa × 5 min as the best process condition to dry abalone. Variations in nutritional parameters compared to casein protein were observed; nevertheless, the high protein quality and digestibility of HPI-assisted dried abalones were maintained to satisfy the metabolic demands of human beings.

  3. Habitat Preferences of Juvenile Abalone (Haliotis mariae Wood, 1828) Along the Dhofar Coast of Oman and Implications for Conservation

    OpenAIRE

    Schalk Willem Petrus de Waal; Mohammed Balkhair; Ali Al-Mashikhi; Salem Khoom

    2012-01-01

    Surveys were conducted along the eastern Dhofar coast of Oman to investigate densities and habitat preferences of juvenile Haliotis mariae (< 3 cm SL). Average density was 0.62 m-2 (SD 0.56); average urchin density was 3.4 urchins m-2 (SD 3.9). Relationships between juvenile abalone densities and small boulders (

  4. National advanced drilling and excavation technologies program: Summary of third meeting of interested Federal agencies

    Energy Technology Data Exchange (ETDEWEB)

    None

    1993-12-07

    The purpose of the meeting was: (1) to discuss a proposal by the Massachusetts Institute of Technology (MIT) outlining a National Advanced Drilling and Excavation Technologies Program, (2) to brief participants on events since the last meeting, and (3) to hear about drilling research activities funded by the Department of Energy. The meeting agenda is included as Attachment B.

  5. Bio-inspired passive actuator simulating an abalone shell mechanism for structural control

    International Nuclear Information System (INIS)

    Yang, Henry T Y; Lin, Chun-Hung; Bridges, Daniel; Randall, Connor J; Hansma, Paul K

    2010-01-01

    An energy dispersion mechanism called 'sacrificial bonds and hidden length', which is found in some biological systems, such as abalone shells and bones, is the inspiration for new strategies for structural control. Sacrificial bonds and hidden length can substantially increase the stiffness and enhance energy dissipation in the constituent molecules of abalone shells and bone. Having been inspired by the usefulness and effectiveness of such a mechanism, which has evolved over millions of years and countless cycles of evolutions, the authors employ the conceptual underpinnings of this mechanism to develop a bio-inspired passive actuator. This paper presents a fundamental method for optimally designing such bio-inspired passive actuators for structural control. To optimize the bio-inspired passive actuator, a simple method utilizing the force–displacement–velocity (FDV) plots based on LQR control is proposed. A linear regression approach is adopted in this research to find the initial values of the desired parameters for the bio-inspired passive actuator. The illustrative examples, conducted by numerical simulation with experimental validation, suggest that the bio-inspired passive actuator based on sacrificial bonds and hidden length may be comparable in performance to state-of-the-art semi-active actuators

  6. Feeding preferences and the nutritional value of tropical algae for the abalone Haliotis asinina.

    Directory of Open Access Journals (Sweden)

    Alex R Angell

    Full Text Available Understanding the feeding preferences of abalone (high-value marine herbivores is integral to new species development in aquaculture because of the expected link between preference and performance. Performance relates directly to the nutritional value of algae--or any feedstock--which in turn is driven by the amino acid content and profile, and specifically the content of the limiting essential amino acids. However, the relationship between feeding preferences, consumption and amino acid content of algae have rarely been simultaneously investigated for abalone, and never for the emerging target species Haliotis asinina. Here we found that the tropical H. asinina had strong and consistent preferences for the red alga Hypnea pannosa and the green alga Ulva flexuosa, but no overarching relationship between protein content (sum of amino acids and preference existed. For example, preferred Hypnea and Ulva had distinctly different protein contents (12.64 vs. 2.99 g 100 g(-1 and the protein-rich Asparagopsis taxiformis (>15 g 100 g(-1 of dry weight was one of the least preferred algae. The limiting amino acid in all algae was methionine, followed by histidine or lysine. Furthermore we demonstrated that preferences can largely be removed using carrageenan as a binder for dried alga, most likely acting as a feeding attractant or stimulant. The apparent decoupling between feeding preference and algal nutritive values may be due to a trade off between nutritive values and grazing deterrence associated with physical and chemical properties.

  7. Effects of dietary carbohydrates sources on lipids compositions in abalone, Haliotis discus hannai Ino

    Science.gov (United States)

    Wang, Weifang; Mai, Kangsen; Zhang, Wenbing; Xu, Wei; Ai, Qinghui; Yao, Chunfeng; Li, Huitao

    2009-09-01

    A study was conducted to evaluate the effects of dietary carbohydrates on triglyceride, cholesterol and fatty acid concentrations in abalone, Haliotis discus hannai Ino. Six semi-purified diets with different carbohydrates (dextrin, heat-treated wheat starch, wheat starch, corn starch, tapioca starch and potato starch, respectively), all containing a carbohydrate level of 33.5%, were fed to abalone (initial shell length: 29.98 mm ± 0.09 mm; initial weight: 3.42 g ± 0.02 g) for 24 weeks in a recirculation system. The results indicate that serum triglyceride concentrations were significantly ( P starch and wheat starch than those fed with corn starch, and serum cholesterol concentrations were significantly ( P starch than those fed with corn starch. Fatty acid C20:4n-6 in the foot muscles were significantly ( P starch, corn starch, tapioca starch and potato starch. Fatty acid C20:4n-6 in hepatopancreas was significantly ( P starch than those fed with corn starch, tapioca starch and potato starch. Fatty acid C22:6n-3 in the foot muscles were significantly ( P starch than those fed with wheat starch and potato starch.

  8. Nutrient uptake efficiency of Gracilaria chilensis and Ulva lactuca in an IMTA system with the red abalone Haliotis rufescens

    Directory of Open Access Journals (Sweden)

    Juan Macchiavello

    2014-07-01

    Full Text Available The current study examined the nutrient uptake efficiency of Ulva lactuca and Gracilaria chilensis cultivated in tanks associated with the wastewater of a land-based abalone culture. The experiments evaluated different seaweed stocking densities (1200, 1900, 2600, and 3200 g m-2 and water exchange rates (60, 80, 125, and 250 L h-1. The results show that both U. lactuca and G. chilensis were efficient in capturing and removing all of the inorganic nutrients originating from the abalone cultivation for all of the tested conditions. Furthermore, an annual experiment was performed with U. lactuca, cultivated at a stocking density of 1900 g m-2 and at a water exchanged rate of 125 L h-1, in order to evaluate seasonal changes in the nutrient uptake efficiency, productivity, and growth rate associated with the wastewater of a land-based abalone culture. The results confirmed high uptake efficiency during the entire year, equivalent to a 100% removal of the NH4, NO3, and PO4 produced by the land-based abalone culture. The growth rate and productivity of U. lactuca presented a marked seasonality, increasing from fall until summer and varying from 0.5 ± 0.2% to 2.6 ± 0.2% d-1 and 10 ± 6.1% to 73.6 ± 8.4% g m-2 d-1 for sustainable growth rate and productivity, respectively. We conclude that there is sufficient evidence that demonstrates the high possibility of changing the traditional monoculture system of abalone in Chile, to a sustainable integrated multi-trophic aquaculture system, generating positive environmental externalities, including the use of U. lactuca as a biofiltration unit.

  9. Decree No. 92-1391 of 30 December 1992 on the National Radioactive Waste Management Agency

    International Nuclear Information System (INIS)

    1992-01-01

    This Decree concerns the arrangement of the National Radioactive Waste Management's (ANDRA) administrative organization. It provides for the resources, type of management and supervision of the new public establishment, as well as for the transfer of assets, rights and obligations which tally with the tasks assigned to ANDRA. The Decree also prescribes that ANDRA must, each year, submit to its Ministerial supervisory authorities a report reviewing its work. (NEA)

  10. Space Education as a Crucial Step Towards the Creation of a National Space Agency

    Science.gov (United States)

    Dionisio Sese, Rogel Mari

    2015-08-01

    The Philippines has recently started in developing and promoting space science education through the Philippine Space Science Education Program (PSSEP) of the Department of Science and Technology (DOST). However, as a developing country, there are numerous challenges in promoting space education to students and teachers. In this paper, we assessed the recent activities done by the PSSEP and demonstrate their effectiveness. In addition, we will expound on the social, political and logistical challenges of promoting space education in an archipelago such as the Philippines. We will also present the preliminary feedback and assessment of the Space Science Program (SSP), a pilot program which teaches space science as a separate subject in the basic educational system from kindergarten to high school. We will also discuss the various teaching strategies we utilized in the SSP that can be adopted depending on the needs and capabilities of the host school. Finally, we discuss the challenges of instituting a formal astronomy and space science course and the issues that needs to be addressed for an effective and sustainable program and how it can be utilized to develop a space-capable workforce for a future Philippine Space Agency.

  11. Molecular cloning of metal-responsive transcription factor-1 (MTF-1 and transcriptional responses to metal and heat stresses in Pacific abalone, Haliotis discus hannai

    Directory of Open Access Journals (Sweden)

    Sang Yoon Lee

    2017-07-01

    Full Text Available Abstract Background Metal-responsive transcription factor-1 (MTF-1 is a key transcriptional regulator playing crucial roles in metal homeostasis and cellular adaptation to diverse oxidative stresses. In order to understand cellular pathways associated with metal regulation and stress responses in Pacific abalone (Haliotis discus hannai, this study was aimed to isolate the genetic determinant of abalone MTF-1 and to examine its expression characteristics under basal and experimentally stimulated conditions. Results The abalone MTF-1 shared conserved features in zinc-finger DNA binding domain with its orthologs; however, it represented a non-conservative shape in presumed transactivation domain region with the lack of typical motifs for nuclear export signal (NES and Cys-cluster. Abalone MTF-1 promoter exhibited various transcription factor binding motifs that would be potentially related with metal regulation, stress responses, and development. The highest messenger RNA (mRNA expression level of MTF-1 was observed in the testes, and MTF-1 transcripts were detected during the entire period of embryonic and early ontogenic developments. Abalone MTF-1 was found to be Cd inducible and highly modulated by heat shock treatment. Conclusion Abalone MTF-1 possesses a non-consensus structure of activation domains and represents distinct features for its activation mechanism in response to metal overload and heat stress. The activation mechanism of abalone MTF-1 might include both indirect zinc sensing and direct de novo synthesis of transcripts. Taken together, results from this study could be a useful basis for future researches on stress physiology of this abalone species, particularly with regard to heavy metal detoxification and thermal adaptation.

  12. The National Security Agency (NSA eavesdropping on Americans
    A programme that is neither legal nor necessary

    Directory of Open Access Journals (Sweden)

    Zmarak Khan

    2006-12-01

    Full Text Available On 16 December 2005, the New York Times reported that the President had authorized the National Security Agency (NSA to spy on Americans, inside the United States, without first obtaining a warrant from the secret FISA court. Although the President has described the NSA activities to be legal and critical to our national security, the programme has started a national controversy, raising questions over its legality and necessity. Consequently, there have been pending legal challenges, congressional investigations, and public outcry over the use of such expansive presidential authority. The legal community, including the American Bar Association, considers the programme illegal. The only district court that has addressed the issue has held it to be an unconstitutional programme that violates FISA. This comment highlights several reasons for why warrantless wiretapping is illegal and unnecessary. The comment also notes public policy reasons against presidential power that is not subject to any checks from Congress or review from the judiciary. Finally, it argues that the President needs to immediately cease the programme; asks Congress to take its oversight responsibility more seriously; and reasons that the judicial review protects against abuse.

  13. Experimental evidence for the effects of polyphenolic compounds from Dictyoneurum californicum Ruprecht (Phaeophyta: Laminariales) on feeding rate and growth in the red abalone Haliotus rufescens Swainson

    Science.gov (United States)

    Winter, Frank C.; Estes, James A.

    1992-01-01

    The effects of polyphenolic compounds from brown algae on grazing and growth rate of the California red abalone Haliotis rufescens Swainson were examined. Abalone consumed three phenolic-poor algal species, Laminaria sinclarii (Harvey) Farlow, Macrocystis pyrifera Agardh, and Nereocystis luetkeana Postels et Ruprecht (mean phenolic content = 0.52% dry mass), at a greater rate than two phenolic-rich species, Dictyoneurum californicum Ruprecht and Cystoseira osmundacea Agardh (mean phenolic content = 4.60% dry mass). This inverse relationship between phenolic content and consumption rate also existed after the algae were macerated and the liquid portion of the blended slurry incorporated in agar discs. However, the correlation between grazing rate and phenolic content imprpve d in this latter experiment, thus suggesting that abalone grazing was deterred significantly by the morphology of L. sinclarii and, to a lesser extent, of M. pyrifera. Polyphenolics extracted from D. californicum reduced abalone grazing rates by 90% when incorporated into agar discs at a concentration of 6 mg·ml−1. Although abalone were unable to maintain body mass when fed ad libitum on macerated M. pyrifera incorporated into agar discs, polyphenolics from D. californicum further inhibited shell growth when added to the discs at 5 mg·ml−1. The abalone ate less of the phenol-containing discs than of the discs lacking phenolics. Our results support findings of several prior studies that polyphenolic compounds from brown algae deter grazing by coastal zone herbivores in the northeast Pacific Ocean.

  14. Effect of dietary lipid on the growth, fatty acid composition and Δ5 Fads expression of abalone ( Haliotis discus hannai Ino) hepatopancreas

    Science.gov (United States)

    Li, Mingzhu; Mai, Kangsen; Ai, Qinghui; He, Gen; Xu, Wei; Zhang, Wenbing; Zhang, Yanjiao; Zhou, Huihui; Liufu, Zhiguo

    2015-04-01

    This study investigated the effect of dietary lipid on the growth, fatty acid composition and Δ5 fatty acyl desaturase genes ( Fads) expression of juvenile abalone ( Haliotis discus hannai Ino) hepatopancreas. Six purified diets were formulated to contain tripalmitin (TP), olive oil (OO, 72.87% 18:1n-9), grape seed oil (GO, 68.67% 18:2n-6), linseed oil (LO, 70.48% 18:3n-3), ARA oil (AO, 41.81% ARA) or EPA oil (EO, 44.09% EPA and 23.67% DAH). No significant difference in survival rate was observed among abalone fed with different diets. Weight gain rate ( WGR) and daily growth rate of shell length ( DGR SL) were significantly increased in abalone fed with diets containing OO, AO and EO, but decreased in abalone fed with LO diet ( P Fads in hepatopancreas of abalone was enhanced by high concentration of 18:3n-3 and suppressed by dietary LC-PUFAs; however it was not affected by dietary high concentration of 18:1n-9 or 18:2n-6. These results provided valuable information for understanding the synthesis of LC-PUFAs and nutritional regulation of Δ5 Fads expression in abalone.

  15. Fiscal 1982 plans of works in National Institute of Radiological Sciences, Science and Technology Agency

    International Nuclear Information System (INIS)

    1982-01-01

    National Institute of Radiological Sciences, since its establishment in 1957, has engaged in the research and other works on the radiation injuries in human bodies, the medical utilization of radiation and the training and education of personnel in the field. The plans of works in fiscal 1982 in the NIRS are described. As special research works, there are the estimation of the degree of danger due to low level radiation for human bodies, environmental radiation exposure due to nuclear facilities, etc., the medical utilization of particle accelerators, and the biological effects of tritium in nuclear fusion reactor development. Ordinary research works include physics, chemistry, genetics, pharmacy, clinical research, etc. In other areas of activities are radiation risk evaluation, radioactivity investigation, technological aid, personnel education and training, and medical work. (Mori, K.)

  16. Currencies, National Images and National Identities: Public Relations for and against Currencies – Historical Experiences from Germany, the Case of the Euro and the Role of Rating Agencies

    Directory of Open Access Journals (Sweden)

    Michael Kunczik

    2013-06-01

    Full Text Available My thesis is that, in the “age of markets” in Europe the Euro is of central importance for creating (or destroying already established structures of European identity (at least in parts of Europe – with Great Britain taking a very remote position. I emphasize the theoretical aspects (Aftalion´s Psychological Theory of Exchange Rates; Simmel: Philosophie des Geldes to emphasize the importance of PR. I concentrate on historical cases – mainly German experiences – e.g. the campaign against the Rubel; the ideas of Ivy Lee; the PR-campaigns of the Nazi-government to fight inflation. The introduction of the German Mark (“die Deutsche Mark”, which became a central aspect of German national identity, and the campaign to give up this currency (“harte Währung” in order to introduce the “weak” Euro. In this context I discuss campaigns against the Euro (“only idiots want the Euro”. In the final remarks I refer to the role of rating agencies and trust in currencies and countries. It is my thesis that the analysts of the rating agencies live in a “world of literary images” and are acting in a completely irresponsible way (but even more incompetent are the politicians accepting the ratings without knowing anything about the problem of commensuration.

  17. National Atomic Energy Agency information about the state nuclear safety and radiation protection in Poland in 1993

    International Nuclear Information System (INIS)

    1994-01-01

    The National Atomic Energy Agency informs about the state of nuclear safety and radiation protection in Poland on the base of inspection and control results of the Nuclear Surveillance institutions in 1993. Several aspects have been taken into account: legal base in the area of nuclear safety and radiation protection, the merit and methods of nuclear surveillance activity, its organization and responsibility, the assessment of radiation protection on the base of environment contamination monitoring, nuclear surveillance in nuclear installations in Poland, control of the safety of nuclear materials and management of nuclear wastes, control of the personnel exposure in nuclear facilities and institutions applying radiation sources. Recommendations concerning these topics have been pointed out as conclusions

  18. The Perennial Environment Observatory by A.N.D.R.A. (the French National Radioactive Waste Management Agency)

    International Nuclear Information System (INIS)

    Leclerc, E.

    2010-01-01

    The Perennial Environment Observatory [Observatoire Perenne de l'Environnement - OPE] is a unique approach and infrastructure developed and implemented by ANDRA, the French National Radioactive Waste Management Agency, as part of its overall project of deep geological disposal for radioactive waste. Its current mission is to assess the initial state of the rural (forest, pasture, open-field and aquatic) environment, prior to repository construction. This will be followed in 2017 (pending construction authorizations) and for a period exceeding a century, by monitoring of any impact the repository may have on the environment. In addition to serving its own industrial purpose of environmental monitoring, ANDRA also opens the OPE approach, infrastructure and acquired knowledge (database...) to the scientific community to support further research on long term evolution of the environment subjected to natural and anthropogenic stresses, and to contribute to a better understanding of the interaction between the various compartments of the environment. (author)

  19. Review of patient safety incidents submitted from Critical Care Units in England & Wales to the UK National Patient Safety Agency.

    Science.gov (United States)

    Thomas, A N; Panchagnula, U; Taylor, R J

    2009-11-01

    We reviewed and classified all patient safety incidents submitted from critical care units in England and Wales to the National Patient Safety Agency for the first quarter of 2008. A total of 6649 incidents were submitted from 141 organisations (median (range) 23 (1-268 incidents)); 786 were unrelated to the critical care episode and 248 were repeat entries. Of the remaining 5615 incidents, 1726 occurred in neonates or babies, 1298 were associated with temporary harm, 15 with permanent harm and 59 required interventions to maintain life or may have contributed to the patient's death. The most common main incident groups were medication (1450 incidents), infrastructure and staffing (1289 incidents) and implementation of care (1047 incidents). There were 2789 incidents classified to more than one main group. The incident analysis highlights ways to improve patient safety and to improve the classification of incidents.

  20. The Public Health Workforce Interests and Needs Survey: The First National Survey of State Health Agency Employees.

    Science.gov (United States)

    Sellers, Katie; Leider, Jonathon P; Harper, Elizabeth; Castrucci, Brian C; Bharthapudi, Kiran; Liss-Levinson, Rivka; Jarris, Paul E; Hunter, Edward L

    2015-01-01

    Public health practitioners, policy makers, and researchers alike have called for more data on individual worker's perceptions about workplace environment, job satisfaction, and training needs for a quarter of a century. The Public Health Workforce Interests and Needs Survey (PH WINS) was created to answer that call. Characterize key components of the public health workforce, including demographics, workplace environment, perceptions about national trends, and perceived training needs. A nationally representative survey of central office employees at state health agencies (SHAs) was conducted in 2014. Approximately 25,000 e-mail invitations to a Web-based survey were sent out to public health staff in 37 states, based on a stratified sampling approach. Balanced repeated replication weights were used to account for the complex sampling design. A total of 10,246 permanently employed SHA central office employees participated in PH WINS (46% response rate). Perceptions about training needs; workplace environment and job satisfaction; national initiatives and trends; and demographics. Although the majority of staff said they were somewhat or very satisfied with their job (79%; 95% confidence interval [CI], 78-80), as well as their organization (65%; 95% CI, 64-66), more than 42% (95% CI, 41-43) were considering leaving their organization in the next year or retiring before 2020; 4% of those were considering leaving for another job elsewhere in governmental public health. The majority of public health staff at SHA central offices are female (72%; 95% CI, 71-73), non-Hispanic white (70%; 95% CI, 69-71), and older than 40 years (73%; 95% CI, 72-74). The greatest training needs include influencing policy development, preparing a budget, and training related to the social determinants of health. PH WINS represents the first nationally representative survey of SHA employees. It holds significant potential to help answer previously unaddressed questions in public health

  1. Patient safety incidents from acupuncture treatments: a review of reports to the National Patient Safety Agency.

    Science.gov (United States)

    Wheway, Jayne; Agbabiaka, Taofikat B; Ernst, Edzard

    2012-01-01

    Acupuncture is frequently employed to treat chronic pain syndromes or other chronic conditions. Nevertheless, there is a growing literature on adverse events (AEs) from treatments including pneumothorax, cardiac tamponade and spinal cord injury. Acupuncture is provided in almost all NHS pain clinics and by an increasing number of GP's and physiotherapists. Considering acupuncture's popularity, its safety has become an important public health issue. To evaluate the harm caused to patients through acupuncture treatments within NHS organisations. The National Reporting and Learning System (NRLS) database was searched for incidents reported from 1st January 2009 to 31st December 2011. The free text fields of all reports received from all healthcare settings and specialties were searched for the keyword 'acupuncture'. All relevant incidents were reviewed to provide a qualitative theme of the harm to patients. 468 patient safety incidents were identified; 325 met our inclusion criteria for analysis. Adverse events reported include retained needles (31%), dizziness (30%), loss of consciousness/unresponsive (19%), falls (4%), Bruising or soreness at needle site (2%), Pneumothorax (1%) and other adverse reactions (12%). The majority (95%) of the incidents were categorised as low or no harm. A number of AEs are recorded after acupuncture treatments in the NHS but the majority is not severe. However, miscategorisation and under-reporting may distort the overall picture. Acupuncture practitioners should be aware of, and be prepared to manage, any significant harm from treatments.

  2. Antibacterial activity and immune responses of a molluscan macrophage expressed gene-1 from disk abalone, Haliotis discus discus.

    Science.gov (United States)

    Bathige, S D N K; Umasuthan, Navaneethaiyer; Whang, Ilson; Lim, Bong-Soo; Won, Seung Hwan; Lee, Jehee

    2014-08-01

    The membrane-attack complex/perforin (MACPF) domain-containing proteins play an important role in the innate immune response against invading microbial pathogens. In the current study, a member of the MACPF domain-containing proteins, macrophage expressed gene-1 (MPEG1) encoding 730 amino acids with the theoretical molecular mass of 79.6 kDa and an isoelectric point (pI) of 6.49 was characterized from disk abalone Haliotis discus discus (AbMPEG1). We found that the characteristic MACPF domain (Val(131)-Tyr(348)) and transmembrane segment (Ala(669)-Ile(691)) of AbMPEG1 are located in the N- and C-terminal ends of the protein, respectively. Ortholog comparison revealed that AbMPEG1 has the highest sequence identity with its pink abalone counterpart, while sequences identities of greater than 90% were observed with MPEG1 members from other abalone species. Likewise, the furin cleavage site KRRRK was highly conserved in all abalone species, but not in other species investigated. We identified an intron-less genomic sequence within disk abalone AbMPEG1, which was similar to other mammalian, avian, and reptilian counterparts. Transcription factor binding sites, which are important for immune responses, were identified in the 5'-flanking region of AbMPEG1. qPCR revealed AbMPEG1 transcripts are present in every tissues examined, with the highest expression level occurring in mantle tissue. Significant up-regulation of AbMPEG1 transcript levels was observed in hemocytes and gill tissues following challenges with pathogens (Vibrio parahemolyticus, Listeria monocytogenes and viral hemorrhagic septicemia virus) as well as pathogen-associated molecular patterns (PAMPs: lipopolysaccharides and poly I:C immunostimulant). Finally, the antibacterial activity of the MACPF domain was characterized against Gram-negative and -positive bacteria using a recombinant peptide. Taken together, these results indicate that the biological significance of the AbMPEG1 gene includes a role in

  3. A decade of illegal fishing in Table Mountain National Park (2000 ...

    African Journals Online (AJOL)

    Illegal fishing activities are reported to be on the increase in South Africa, including in its marine protected areas (MPAs). Research is presented on the nature and the scale of illegal fishing in Table Mountain National Park (TMNP) by analysing the numbers of abalone Haliotis midae and West Coast rock lobster Jasus ...

  4. Genetic characterization of five hatchery populations of the Pacific Abalone (Haliotis discus hannai) using microsatellite markers.

    Science.gov (United States)

    An, Hye Suck; Lee, Jang Wook; Kim, Hyun Chul; Myeong, Jeong-In

    2011-01-01

    The Pacific abalone, Haliotis discus hannai, is a popular food in Eastern Asia. Aquacultural production of this species has increased because of recent resource declines, the growing consumption, and ongoing government-operated stock release programs. Therefore, the genetic characterization of hatchery populations is necessary to maintain the genetic diversity of this species and to develop more effective aquaculture practices. We analyzed the genetic structures of five cultured populations in Korea using six microsatellite markers. The number of alleles per locus ranged from 15 to 64, with an average of 23.5. The mean observed and expected heterozygosities were 0.797 and 0.904, respectively. The inbreeding coefficient F(IS) ranged from 0.054 to 0.184 (mean F(IS) = 0.121 ± 0.056). The genetic differentiation across all populations was low but significant (overall F(ST) = 0.009, P discus hannai fisheries and the aquaculture industry.

  5. The combination between cations and sulfated polysaccharide from abalone gonad (Haliotis discus hannai Ino).

    Science.gov (United States)

    Guo, Yiming; Cong, Shuang; Zhao, Jun; Dong, Yingying; Li, Tingting; Zhu, Beiwei; Song, Shuang; Wen, Chengrong

    2018-05-15

    Effects of cations (Na + , K + , Ca 2+ , Mg 2+ ) on the structure of abalone gonad sulfated polysaccharide (AGSP) were studied by means of Congo red test, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and scanning electron microscope (SEM). The results showed that the local ordered helical conformation was observed in AGSP. The cations could combine with anionic groups in AGSP by ionic bonds, which caused the weakening of electrostatic repulsion and crosslinking of molecular chains. Furthermore, the effects of divalent cations on the conformation were more obvious than that of monovalent cations, and divalent cations led to the aggregation of AGSP due to the more interaction sites. In short, AGSP molecular chains were crosslinked through ionic bonds after adding cations, and, divalent cations could induce the aggregation of AGSP by electrostatic interactions. This study will provide valuable insights for the further research on AGSP conformation. Copyright © 2018 Elsevier Ltd. All rights reserved.

  6. ANDRA - National Radioactive Waste Management Agency. Activity report 2007. Management report - Financial statements at December 31, 2007

    International Nuclear Information System (INIS)

    2008-09-01

    Created in 1979 within the CEA, the National Radioactive Waste Management Agency (ANDRA) was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied; - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories. This mission includes as well a public service mission in terms of i) collection of waste of the 'small-scale nuclear activities' producers or owners (including the so-called 'household' radioactive waste, i.e. waste owned by private individuals) and ii) clean-up and rehabilitation of orphan polluted sites; - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This mission includes as well an active policy of dialogue with stakeholders both at national and local level. This document is the activity report with the management and financial statements report of the Andra for the year 2007

  7. ANDRA - National Radioactive Waste Management Agency. Annual sustainable development and activity report 2012. Management report and financial statements 2012

    International Nuclear Information System (INIS)

    2013-01-01

    Created in 1979 within the CEA, the National Radioactive Waste Management Agency (ANDRA) was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied; - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories. This mission includes as well a public service mission in terms of i) collection of waste of the 'small-scale nuclear activities' producers or owners (including the so-called 'household' radioactive waste, i.e. waste owned by private individuals) and ii) clean-up and rehabilitation of orphan polluted sites; - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This mission includes as well an active policy of dialogue with stakeholders both at national and local level. This document is the activity and Sustainable Development Report, with the management and financial statements report, of the Andra for the year 2012

  8. ANDRA - National Radioactive Waste Management Agency. Annual sustainable development and activity report 2011. Management report and financial statements 2011

    International Nuclear Information System (INIS)

    2012-01-01

    Created in 1979 within the CEA, the National Radioactive Waste Management Agency (ANDRA) was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied; - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories. This mission includes as well a public service mission in terms of i) collection of waste of the 'small-scale nuclear activities' producers or owners (including the so-called 'household' radioactive waste, i.e. waste owned by private individuals) and ii) clean-up and rehabilitation of orphan polluted sites; - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This mission includes as well an active policy of dialogue with stakeholders both at national and local level. This document is the activity and Sustainable Development Report, with the management and financial statements report, of the Andra for the year 2011

  9. Antimicrobial peptide, hdMolluscidin, purified from the gill of the abalone, Haliotis discus.

    Science.gov (United States)

    Seo, Jung-Kil; Go, Hye-Jin; Kim, Chan-Hee; Nam, Bo-Hye; Park, Nam Gyu

    2016-05-01

    A 4.7 kDa antimicrobial peptide was purified from the acidified gill extract of the Abalone, Haliotis discus, by cation-exchange and C18 reversed-phase high performance liquid chromatography (HPLC). Comparison of the amino acid sequences and molecular weight of this peptide with those of other known antimicrobial peptides revealed that this antimicrobial peptide have high sequence homology with that of cgMolluscidin and was designated hdMolluscidin. hdMolluscidin is composed of 46 amino acid residues containing several dibasic residue repeats like KK or K-R. hdMolluscidin showed potent antimicrobial activity against both Gram-positive bacteria including Bacillus subtilis and Staphylococcus aureus (minimal effective concentrations [MECs]; 0.8-19.0 μg/mL) and Gram-negative bacteria including Aeromonas hydrophila, Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica, Shigella flexneri, and Vibrio parahemolyticus ([MECs]; 1.0-4.0 μg/mL) without hemolytic activity. However, hdMolluscidin did not show any significant activity against Candida albicans. The secondary structural prediction suggested that hdMolluscidin might not form an ordered or an amphipathic structure. hdMolluscidin did not show membrane permeabilization or leakage ability. The full-length hdMolluscidin cDNA contained 566-bp, including a 5'-untranslated region (UTR) of 63-bp, a 3'-UTR of 359-bp, and an open reading frame of 144-bp encoding 47 amino acids (containing Met). cDNA study of hdMolluscidin suggests that it is expressed as a mature peptide. Our results indicate that hdMolluscidin could relate to the innate immune defenses in abalone and it may not act directly on bacterial membrane. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Characterization and spatiotemporal expression of gonadotropin-releasing hormone in the Pacific abalone, Haliotis discus hannai.

    Science.gov (United States)

    Kim, Tae Ha; Kim, Mi Ae; Kim, Kyeong Seop; Kim, Jae Won; Lim, Han Kyu; Lee, Jung Sick; Sohn, Young Chang

    2017-07-01

    Gonadotropin-releasing hormone (GnRH) is a key neuropeptide regulating reproduction in humans and other vertebrates. Recently, GnRH-like cDNAs and peptides were reported in marine mollusks, implying that GnRH-mediated reproduction is an ancient neuroendocrine system that arose prior to the divergence of protostomes and deuterostomes. Here, we evaluated the reproductive control system mediated by GnRH in the Pacific abalone Haliotis discus hannai. We cloned a prepro-GnRH cDNA (Hdh-GnRH) from the pleural-pedal ganglion (PPG) in H. discus hannai, and analyzed its spatiotemporal gene expression pattern. The open reading frame of Hdh-GnRH encodes a protein of 101 amino acids, consisting of a signal peptide, a GnRH dodecapeptide, a cleavage site, and a GnRH-associated peptide. This structure and sequence are highly similar to GnRH-like peptides reported for mollusks and other invertebrates. Quantitative polymerase chain reaction demonstrated that Hdh-GnRH mRNA was more strongly expressed in the ganglions (PPG and cerebral ganglion [CG]) than in other tissues (gonads, gills, intestine, hemocytes, muscle, and mantle) in both sexes. In females, the expression levels of Hdh-GnRH mRNA in the PPG and branchial ganglion (BG) were significantly higher at the ripe and partial spent stages than at the early and late active stages. In males, Hdh-GnRH mRNA levels in the BG showed a significant increase in the partial spent stage. Unexpectedly, Hdh-GnRH levels in the CG were not significantly different among the examined stages in both sexes. These results suggest that Hdh-GnRH mRNA expression profiles in the BG and possibly the PPG are tightly correlated with abalone reproductive activities. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. The Texts of the Agreements Between the International Atomic Energy Agency, the United Nations and the Federal Government of the Republic of Austria Regarding the Headquarters Seat and Related Agreements

    International Nuclear Information System (INIS)

    1983-01-01

    The texts of seven agreements concluded between the Agency and the Republic of Austria, as well as between the Agency, the United Nations and the Republic of Austria, are reproduced in this document for the information of all Members

  12. Allograft inflammatory factor-1 in disk abalone (Haliotis discus discus): molecular cloning, transcriptional regulation against immune challenge and tissue injury.

    Science.gov (United States)

    De Zoysa, Mahanama; Nikapitiya, Chamilani; Kim, Yucheol; Oh, Chulhong; Kang, Do-Hyung; Whang, Ilson; Kim, Se-Jae; Lee, Jae-Seong; Choi, Cheol Young; Lee, Jehee

    2010-08-01

    Here, we report the identification and characterization of allograft inflammatory factor-1 (AIF-1) from disk abalone Haliotis discus discus that was denoted as AbAIF-1. The full-length cDNA of AbAIF-1 consists of a coding region (453 bp) for 151 amino acids with a 17 kDa molecular mass. Analysis of AbAIF-1 sequence showed that it shares characteristic two EF hand Ca(+2)-binding motifs. Results from phylogenetic analysis further confirm that AbAIF-1 is a member of the AIF-1 family similar to invertebrate and vertebrate counterparts suggesting it has high evolutional conservation. Tissue-specific expression and transcriptional regulation of AbAIF-1 were analyzed after bacteria (Vibrio alginolyticus, Vibrio parahemolyticus and Lysteria monocytogenes), viral hemorrhagic septicemia virus (VHSV) immune challenge and during tissue injury by quantitative real-time PCR. It is shown that the expression of AbAIF-1 mRNA was expressed ubiquitously in all selected tissues in constitutive manner showing the highest level in hemocytes. Upon bacteria and VHSV challenge, AbAIF-1 showed the significant up-regulation in hemocytes than gills. After the tissue injury in shell and mantle, AbAIF-1 and antioxidant selenium-dependant glutathione peroxidase (SeGPx) transcripts were significantly upregulated in abalone hemocytes. Taken together, these findings suggest that AIF-1 could response against the pathogenic challenge or tissue injury in abalone like mollusks. Also, AbAIF-1 may involve in wound healing and shell repair after the tissue injury of abalone. Copyright 2010 Elsevier Ltd. All rights reserved.

  13. Transcriptional up-regulation of a novel ferritin homolog in abalone Haliotis discus hannai Ino by dietary iron.

    Science.gov (United States)

    Wu, Chenglong; Zhang, Wenbing; Mai, Kangsen; Xu, Wei; Wang, Xiaojie; Ma, Hongming; Liufu, Zhiguo

    2010-11-01

    A novel cDNA encoding ferritin (HdhNFT) was cloned from the hepatopancreas of abalone, Haliotis discus hannai Ino. The deduced protein contains 171 amino acid residues with a predicted molecular mass (MW) about 19.8 kDa and theoretical isoelectric point (pI) of 4.792. Amino acid alignment revealed that HdhNFT shared high similarity with other known ferritins. The HdhNFT contained a highly conserved motif for the ferroxidase center, which consists of seven residues of a typical vertebrate heavy-chain ferritin with a typical stem-loop structure. HdhNFT mRNA contains a 27 bp iron-responsive element (IRE) in the 5'-untranslated region. This IRE exhibited 82.14% similarity with abalone H. discus discus and 78.57% similarity with Pacific oyster Crassostrea gigas IREs. By real-time PCR assays, the mRNA transcripts of HdhNFT were found to be higher expressed in kidney, hepatopancreas, gill, mantle and muscle than in haemocytes and gonad. Moreover, mRNA expression levels of HdhNFT in the hepatopancreas and haemocytes were measured by real-time PCR in abalone fed with graded levels of dietary iron (29.2, 65.7, 1267.2 and 6264.7 mg/kg). Results showed that the expression of the HdhNFT mRNA increased with dietary iron contents. Furthermore, the maximum value of the HdhNFT mRNA was found in the treatment with 6264.7 mg/kg of dietary iron. These data indicated that dietary iron can up-regulate HdhNFT at transcriptional level in abalone. Copyright © 2010 Elsevier Inc. All rights reserved.

  14. Effects of temperature and salinity on survival, growth and DNA methylation of juvenile Pacific abalone, Haliotis discus hannai Ino

    Science.gov (United States)

    Kong, Ning; Liu, Xiao; Li, Junyuan; Mu, Wendan; Lian, Jianwu; Xue, Yanjie; Li, Qi

    2017-09-01

    Temperature and salinity are two of the most potent abiotic factors influencing marine mollusks. In this study, we investigated the individual and combined effects of temperature and salinity on the survival and growth of juvenile Pacific abalone, Haliotis discus hannai Ino, and also examined the DNA methylation alteration that may underpin the phenotypic variation of abalone exposed to different rearing conditions. The single-factor data showed that the suitable ranges of temperature and salinity were 16-28°C at a constant salinity of 32, and 24-40 at a constant temperature of 20°C, respectively. The two-factor data indicated that both survival and growth were significantly affected by temperature, salinity and their interaction. The optimal temperature-salinity combination for juveniles was 23-25°C and 30-36. To explore environment-induced DNA methylation alteration, the methylation-sensitive amplified polymorphism (MSAP) technique was used to analyze the genomic methylation profiles of abalone reared in optimal and adverse conditions. Neither temperature nor salinity induced evident changes in the global methylation level, but 67 and 63 differentially methylated loci were identified in temperature and salinity treatments, respectively. The between-group eigen analysis also showed that both temperature and salinity could induce epigenetic differentiation in H. discus hannai Ino. The results of our study provide optimal rearing conditions for juvenile H. discus hannai Ino, and represent the first step toward revealing the epigenetic regulatory mechanism of abalone in response to thermal and salt stresses.

  15. Proteomic profiling of eggs from a hybrid abalone and its parental lines: Haliotis discus hannai Ino and Haliotis gigantea.

    Science.gov (United States)

    Di, Guilan; Luo, Xuan; Huang, Miaoqin; Chen, Jun; Kong, Xianghui; Miao, Xiulian; Ke, Caihuan

    2015-12-01

    Proteomic analysis was performed on the eggs of hybrid abalone and their corresponding parental lines. A total of 915 ± 19 stained protein spots were detected from Haliotis discus hannai♀ × H. discus hannai♂ (DD), 935 ± 16 from H. gigantea♀ × H. gigantea♂ (GG) and 923 ± 13 from H. gigantea♀ × H. discus hannai♂ (GD). The spots from DD and GD were clustered together. The distance between DD and GG was maximal by hierarchical cluster analysis. A total of 112 protein gel spots were identified; of these, 59 were abalone proteins. The proteins were involved in major biological processes including energy metabolism, proliferation, apoptosis, signal transduction, immunity, lipid metabolism, electron carrier proteins, protein biosynthesis and decomposition, and cytoskeletal structure. Three of 20 differential expression protein spots involved in energy metabolism exhibited as upregulated in GD, 13 spots exhibited additivity, and four spots exhibited as downregulated in the offspring. Eleven protein spots were expressed at the highest level in DD. The proteins involved in stress responses included superoxide dismutase, peroxiredoxin 6, thioredoxin peroxidase and glutathione-S-transferase. Two of seven differential expression protein spots involved in response to stress exhibited as upregulated in GD, three exhibited additivity, and two exhibited as downregulated. These results might suggest that proteomic approaches are suitable for the analysis of hybrids and the functional prediction of abalone hybridization. © 2015 Stichting International Foundation for Animal Genetics.

  16. BRICHOS domain-containing leukocyte cell-derived chemotaxin 1-like cDNA from disk abalone Haliotis discus discus.

    Science.gov (United States)

    Kim, Yucheol; De Zoysa, Mahanama; Lee, Youngdeuk; Whang, Ilson; Lee, Jehee

    2010-11-01

    A BRICHOS domain-containing leukocyte cell-derived chemotaxin 1-like cDNA was cloned from the disk abalone (Haliotis discus discus) and designated as AbLECT-1. A full-length (705 bp) of AbLECT-1 cDNA was composed of a 576 bp open reading frame that translates into a putative peptide of 192 amino acids. Deduced amino acid sequence of AbLECT-1 had 15.5- and 27.8% identity and similarity to human LECT-1, respectively. Quantitative real-time PCR analysis results showed that the mRNA of AbLECT-1 was constitutively expressed in abalone hemocytes, gills, mantle, muscle, digestive tract and hepatopancreas in a tissue-specific manner. Moreover, the AbLECT-1 transcription level was induced in hemocytes after challenge with Vibrio alginolyticus, Vibrio parahemolyticus, and Listeria monocytogenes suggesting that it may be involved in immune response reactions in abalone. Copyright 2010 Elsevier Ltd. All rights reserved.

  17. Isolation and identification of lactic acid bacteria from abalone (Haliotis asinina as a potential candidate of probiotic

    Directory of Open Access Journals (Sweden)

    YAYAN SOFYAN

    2010-01-01

    Full Text Available Sarkono, Faturrahman, Sofyan Y. 2010. Isolation and identification of lactic acid bacteria from abalone (Haliotis asinina as a potential candidate of probiotic. Nusantara Bioscience 2: 38-42. The purpose of this study was to isolate, select and characterize lactic acid bacteria (LAB from abalone as a potential candidate probiotic in abalone cultivation system. Selective isolation of LAB performed using de Man Rogosa Sharpe medium. LAB isolate that potential as probiotics was screened. Selection was based on its ability to suppress the growth of pathogenic bacteria, bacterial resistance to acidic conditions and bacterial resistance to bile salts (bile. Further characterization and identification conducted to determine the species. The results showed that two of the ten isolates potential to be developed as probiotic bacteria that have the ability to inhibit several pathogenic bacteria such as Eschericia coli, Bacillus cereus dan Staphylococus aureus, able to grow at acidic condition and bile tolerance during the incubation for 24 hour. Based on the API test kit, the both of isolate identified as members of the species Lactobacillus paracasei ssp. paracasei.

  18. Quality in Cross-Border Higher Education and Challenges for the Internationalization of National Quality Assurance Agencies in the Asia-Pacific Region: The Taiwanese Experience

    Science.gov (United States)

    Hou, Angela Yung-chi

    2014-01-01

    Cross-border higher education has created a need to build capacity -- particularly in the internationalization dimension -- for national quality assurance agencies to evaluate cross-border education provided by foreign educational providers, or jointly by local and foreign institutions. This is quickly becoming a key issue in the Asia-Pacific…

  19. Characterization of national food agency shrimp and plaice reference materials for trace elements and arsenic species by atomic and mass spectrometric techniques

    DEFF Research Database (Denmark)

    Larsen, Erik Huusfeldt; Pedersen, Gitte Alsing; McLaren, J. W.

    1997-01-01

    The National Food Agency (NFA) of Denmark has produced and characterized NFA Plaice and NFA Shrimp reference materials (RMs) for the control of the accuracy of trace element and arsenic species determinations in similar seafood samples, The physical preparation of the materials included dissectio...

  20. Involvement of clip-domain serine protease in the anti-Vibrio immune response of abalone (Haliotis discus hannai)-Molecular cloning, characterization and functional analysis.

    Science.gov (United States)

    Hu, Jian-Jian; Chen, Yu-Lei; Duan, Xue-Kun; Jin, Teng-Chuan; Li, Yue; Zhang, Ling-Jing; Liu, Guang-Ming; Cao, Min-Jie

    2018-01-01

    Vibrio parahemolyticus (V. parahemolyticus) is a major pathogen for abalone, an important economical shellfish in coastal area of China. There is little known about the abalone innate immune system against pathogen infection. Clip-domain serine proteases (cSPs) are increasingly recognized to play important roles in host immune defense in invertebrates. In this study, we cloned a cSP (Hdh-cSP) from abalone (Haliotis discus hannai). We found out that Hdh-cSP was widely expressed in multiple tissues of abalone, with highest level in the immune-like organ, hepatopancreas. V. parahemolyticus infection induced significantly elevated expression of Hdh-cSP in addition to better-characterized innate immune component genes including Rel/NF-κB, allograft inflammatory factor (ALInFa), macrophage expressed protein (MEP) and caspase-8. Importantly, the silencing of Hdh-cSP reduced the expression of these genes, suggesting that Hdh-cSP was an upstream regulatory factor in V. parahemolyticus infection. Further analysis showed that apoptosis of hemocytes was inhibited when the transcription of Hdh-cSP was knocked down, suggesting that Hdh-cSP participated in cell apoptosis by regulation of caspase 8 expression in V. parahemolyticus infection. Therefore, our study established an important role of cSP in the innate immunity against V. parahemolyticus infection in abalone. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. National Strategic Environmental Assessment for aquaculture development in South Africa: GIS analysis for identifying optimal areas for marine and freshwater aquaculture development

    CSIR Research Space (South Africa)

    Snyman-van der Walt, Luanita

    2017-06-01

    Full Text Available + rationale •10 areas -> 8 areas 20 Suitable area screening Durban-Richards Bay Dusky kob East London Dusky kob Abalone Port Elizabeth Dusky kob Abalone Oysters Mussels Mossel Bay Abalone Oysters Mussels Hermanus-Arniston Abalone Atlantic salmon Velddrif...-Saldanha Atlantic salmon Abalone Oysters Mussels Strandfontein- Lamberts Bay Atlantic salmon Abalone Orange-Hondeklip Bay Atlantic salmon Abalone Oysters 21 Conclusion & way forward • Specialist investigation Biodiversity & Ecology Heritage Visual &aesthetic...

  2. Hypertension and treatment outcomes in Palestine refugees in United Nations Relief and Works Agency primary health care clinics in Jordan.

    Science.gov (United States)

    Khader, A; Farajallah, L; Shahin, Y; Hababeh, M; Abu-Zayed, I; Zachariah, R; Kochi, A; Kapur, A; Harries, A D; Shaikh, I; Seita, A

    2014-10-01

    In six United Nations Relief and Works Agency (UNRWA) primary health care clinics in Jordan serving Palestine refugees diagnosed with hypertension, to determine the number, characteristics, programme outcomes and measures of disease control for those registered up to 30 June, 2013, and in those who attended clinic in the second quarter of 2013, the prevalence of disease-related complications between those with hypertension only and hypertension combined with diabetes mellitus. Retrospective cohort study with programme and outcome data collected and analysed using E-Health. There were 18 881 patients registered with hypertension with females (64%) and persons aged ≥ 40 years (87%) predominating. At baseline, cigarette smoking was recorded in 17%, physical inactivity in 48% and obesity in 71% of patients. 77% of all registered patients attended clinic in the second quarter of 2013; of these, 50% had hypertension and diabetes and 50% had hypertension alone; 9% did not attend the clinics and 10% were lost to follow-up. Amongst those attending clinic, 92% had their blood pressure measured, of whom 83% had blood pressure <140/90 mm Hg. There were significantly more patients with hypertension and diabetes (N = 966, 13%) who had disease-related complications than patients who had hypertension alone (N = 472, 6%) [OR 2.2, 95% CI 2.0-2.5], and these differences were found for both males [18% vs. 10%, OR 1.9, 95% CI 1.6-2.2] and females [11% vs. 5%, OR 2.4, 95% CI 2.1-2.9]. Large numbers of Palestine refugees are being registered and treated for hypertension in UNRWA primary health care clinics in Jordan. Cohort analysis and E-Health can be used to regularly assess caseload, programme outcomes, clinic performance, blood pressure control and cumulative prevalence of disease-related complications. Current challenges include the need to increase clinic attendance and attain better control of blood pressure. © 2014 John Wiley & Sons Ltd.

  3. Re-inventing Nigeria's Public Sector: A Review of National Agency for Food, Drug Administration and Control (NAFDAC

    Directory of Open Access Journals (Sweden)

    Chinyeaka Justine Igbokwe-Ibeto

    2015-06-01

    Full Text Available Public  Over the years, the efficiency and effectiveness of Nigeria’s public sector has been a subject of debate. However, in recent time, the organizational performance and service delivery of National Agency for Food, Drug Administration and Control (NAFDAC have been a success story. Within the framework of New Public Management (NPM theory, the study investigates the secrete behind the degree of success achieved by NAFDAC with the aim of recommending such to other public sector organizations in Nigeria which has over the year’s demonstrated lack of zeal for service delivery. The study relied heavily on primary and secondary data. Yamani’s formula for sample size determination was used to select a sample of 133 employees from NAFDAC Lagos office out of a total of 200. Weighted mean and chi-square statistical tools was used to determine the independence or otherwise of the variables under investigation. It is the position of the study that NPM has enhanced NAFDAC’s performance and service delivery. It concludes that since the traditional public administration theories has failed to deliver the much needed public goods and services, it is therefore imperative to reinvent Nigeria’s public sector in line with (NPM international best practices so as to reposition the Nigerian public sector for the challenges of a modern and rapidly changing world. However, while change is desirable, we feel there is need to exercise caution on account of the peculiar nature and character of the Nigerian state and society. Reinventing the country’s public sector should progress slowly and wisely.

  4. Dietary ascorbic acid modulates the expression profile of stress protein genes in hepatopancreas of adult Pacific abalone Haliotis discus hannai Ino.

    Science.gov (United States)

    Wu, Chenglong; Wang, Jia; Xu, Wei; Zhang, Wenbing; Mai, Kangsen

    2014-12-01

    This study was conducted to investigate the effects of dietary ascorbic acid (AA) on transcriptional expression patterns of antioxidant proteins, heat shock proteins (HSP) and nuclear factor kappa B (NF-κB) in the hepatopancreas of Pacific abalone Haliotis discus hannai Ino (initial average length: 84.36 ± 0.24 mm) using real-time quantitative PCR assays. L-ascorbyl-2-molyphosphate (LAMP) was added to the basal diet to formulate four experimental diets containing 0.0, 70.3, 829.8 and 4967.5 mg AA equivalent kg(-1) diets, respectively. Each diet was fed to triplicate groups of adult abalone in acrylic tanks (200 L) in a flow-through seawater system. Each tank was stocked with 15 abalone. Animals were fed once daily (17:00) to apparent satiation for 24 weeks. The results showed that the dietary AA (70.3 mg kg(-1)) could significantly up-regulate the expression levels of Cu/Zn superoxide dismutase (SOD), catalase (CAT), glutathione-S-transferase (GST), feritin (FT) and heat shock protein 26 (HSP26) in the hepatopancreas of abalone in this treatment compared to the controls. However, the expression levels of Mn-SOD, glutathione peroxidase (GPX), thioredoxin peroxidase (TPx), selenium-binding protein (SEBP), HSP70 and HSP90 were significantly down-regulated. Compared with those in the group with 70.3 mg kg(-1) dietary AA, the expression levels of CAT, GST and HSP26 were decreased in abalone fed with very high dietary AA (4967.5 mg kg(-1)). In addition, significant up-regulations of expression levels of Mn-SOD, GPX, TPx, SEBP, FT, HSP70, HSP90 and NF-κB were observed in abalone fed with apparently excessive dietary AA (829.8 and 4967.5 mg kg(-1)) as compared to those fed 70.3 mg kg(-1) dietary AA. These findings showed that dietary AA influenced the expression levels of antioxidant proteins, heat shock proteins and NF-κB in the hepatopancreas of abalone at transcriptional level. Levels of dietary AA that appeared adequate (70.3 mg kg(-1)) reduced the oxidative stress

  5. Transforming the Roles of a Public Extension Agency to Strengthen Innovation: Lessons from the National Agricultural Extension Project in Bangladesh

    NARCIS (Netherlands)

    Chowdhury, A.H.; Odame, H.H.; Leeuwis, C.

    2014-01-01

    Purpose: The rapidly evolving nature of agricultural innovation processes in low-income countries requires agricultural extension agencies to transform the classical roles that previously supported linear information dissemination and adoption of innovation. In Bangladesh, strengthening agricultural

  6. BLM National Surface Management Agency: Area Polygons, Withdrawal Area Polygons, and Special Public Purpose Withdrawal Area Polygons

    Data.gov (United States)

    Federal Geographic Data Committee — The SMA implementation is comprised of one feature dataset, with several polygon feature classes, rather than a single feature class. SurfaceManagementAgency: The...

  7. Structural characterization and osteogenic bioactivity of a sulfated polysaccharide from pacific abalone (Haliotis discus hannai Ino).

    Science.gov (United States)

    Song, Shuang; Zhang, Bao; Wu, Sufeng; Huang, Lu; Ai, Chunqing; Pan, Jinfeng; Su, Yi-Cheng; Wang, Zhongfu; Wen, Chengrong

    2018-02-15

    Bone morphogenic protein-2 (BMP-2) is known to promote osteogenesis. To find novel adjuvants to enhance the activity of BMP-2, the present study investigated the structure BMP-2-induced osteogenic activity of a water-soluble polysaccharide from the gonad of pacific abalone (Haliotis discus hannai Ino) named AGSP. Through analysis of aldobiouronic acids released from AGSP, monosaccharide composition comparison of AGSP and its reduced product, and methylation analysis and NMR analysis of AGSP and its desulfated derivative, the main structure residue of AGSP was determined as →3)-GlcA(1→3)-Gal(1→ with sulfated branches comprised of prevelant Gal and minor Glc, and →4)-β-GlcA(1→2)-α-Man(1→ residue was also found. AGSP possessed a sulfate content of 12.4% with a relative molecular weight of 6.6kDa. AGSP strengthened alkaline phosphatase activity induced by BMP-2 in a dose dependent manner at 10-200μg/mL with 425% enhancement being observed at 200μg/mL, indicating AGSP could be an adjuvant candidate to enhance osteogenic activity of BMP-2. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Effects of polysaccharides from abalone viscera (Haliotis discus hannai Ino) on MGC 803 cells proliferation.

    Science.gov (United States)

    Zhang, Rui-Juan; Shi, Yan; Zheng, Jing; Mao, Xiao-Mei; Liu, Zhi-Yu; Chen, Qing-Xi; Wang, Qin

    2018-01-01

    The polysaccharides (AVP) was obtained from abalone (Haliotis discus hannai Ino) viscera, using the alkaline protease to enzymolysis, sevage method and repeated freezing and thawing method to remove protein and hydrogen peroxide method to depigment. The total sugar content was 46.27±1.5% and uronic acid, sulfate radical, hexosamine and protein contents were 17.44±0.22%, 16.98±0.15%, 0.65±0.02% and 1.64±0.13% in AVP respectively. The main monosaccharide compositions of AVP were d-galactose, d-xylose, d-mannose, d-glucose and d-glucuronic acid. MTT assay showed AVP had a significant anti-tumor activity to gastric carcinoma cells, especially to MGC 803, while it had no influence upon proliferation of normal stomach cells GES 1. The results of Morphological changes, cell migration ability and AO/EB staining indicated that MGC803 cells underwent apoptosis in a dose-dependent manner induced by AVP. Moreover, the western blotting results showed that the expressions of survivin, Bcl-2 and VEGF were decreased, while the expression of Bax and p53 were increased in a dose-dependent manner of AVP. The results suggested that AVP might be a potential anti-tumor agent securely and naturally. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Characterization of defensin gene from abalone Haliotis discus hannai and its deduced protein

    Science.gov (United States)

    Hong, Xuguang; Sun, Xiuqin; Zheng, Minggang; Qu, Lingyun; Zan, Jindong; Zhang, Jinxing

    2008-11-01

    Defensin is one of preserved ancient host defensive materials formed in biological evolution. As a regulator and effector molecule, it is very important in animals’ acquired immune system. This paper reports the defensin gene from the mixed liver and kidney cDNA library of abalone Haliotis discus hannai Ino. Sequence analysis shows that the gene sequence of full-length cDNA encodes 42 mature peptides (including six Cys), molecular weight of 4 323 Da, and pI of 8.02. Amino acid sequence homology analysis shows that the peptides are highly similar (70% in common) to other insects defensin. Because of a typical insect-defensin structural character of mature peptide in the secondary structure, the polypeptide named Haliotis discus defensin (hd-def), a novel of antimicrobial peptides, belongs to insects defensin subfamily. The RT-PCR result of Haliotis discus defensin shows that the gene can be expressed only in the hepatopancreas by Gram-negative and positive bacteria stimulation, which is ascribed to inducible expression. Therefore, it is revealed that the Haliotis discus defensin gene expression was related to the antibacterial infection of Haliotis discus hannai Ino.

  10. Underwater adhesion of abalone: The role of van der Waals and capillary forces

    International Nuclear Information System (INIS)

    Lin, A.Y.M.; Brunner, R.; Chen, P.Y.; Talke, F.E.; Meyers, M.A.

    2009-01-01

    The observation of the pedal foot of the red abalone Haliotis rufescens reveals the presence of micrometer-scaled setae terminating in nanometer-sized cylindrical fibrils, with some resemblance to those found on the gecko foot. Atomic force microscopy (AFM) pull-off force measurements on a single seta are compared with theoretical estimates for van der Waals attraction obtained through the Johnson-Kendall-Roberts (JKR) equation, approximately 600 nN, and show agreement. The use of the JKR equation is justified through an analysis of the shape of the fibril extremities (parabolic) as well as their diameter (∼200 nm). Measurements under varying humidity conditions indicate that additional capillary interactions play a role, since the pull-off force increases with humidity. It is proposed that both van der Waals and capillary forces play a role in the attachment mechanism of H. rufescens, effectively enabling suction to reach its theoretical limit. Bulk pull-off force measurements on entire live animals yield an average detachment stress of 115 kPa, consistent with theoretical estimates. The setae and nanoscale fibril terminations enable compliance to surfaces with a variety of roughnesses, effectively sealing the interface, in addition to providing capillary and van der Waals forces.

  11. Theoretical characterization of a model of aragonite crystal orientation in red abalone nacre

    International Nuclear Information System (INIS)

    Coppersmith, S N; Gilbert, P U P A; Metzler, R A

    2009-01-01

    Nacre, commonly known as mother-of-pearl, is a remarkable biomineral that in red abalone consists of layers of 400 nm thick aragonite crystalline tablets confined by organic matrix sheets, with the [0 0 1] crystal axes of the aragonite tablets oriented to within ±12 deg. from the normal to the layer planes. Recent experiments demonstrate that greater orientational order develops over a distance of tens of layers from the prismatic boundary at which nacre formation begins. Our previous simulations of a model in which the order develops because of differential tablet growth rates (oriented tablets growing faster than misoriented ones) yield patterns of tablets that agree qualitatively and quantitatively with the experimental measurements. This paper presents an analytical treatment of this model, focusing on how the dynamical development and eventual degree of order depend on model parameters. Dynamical equations for the probability distributions governing tablet orientations are introduced whose form can be determined from symmetry considerations and for which substantial analytic progress can be made. Numerical simulations are performed to relate the parameters used in the analytic theory to those in the microscopic growth model. The analytic theory demonstrates that the dynamical mechanism is able to achieve a much higher degree of order than naive estimates would indicate

  12. Exploratory analysis of the relationship between home health agency engagement in a national campaign and reduction in acute care hospitalization in US home care patients.

    Science.gov (United States)

    Esslinger, E Eve; Schade, Charles P; Sun, Cynthia K; Sun, Ying Hua; Manna, Jill; Hall, Bethany Knowles; Wright, Shanen; Hannah, Karen L; Lynch, Janet R

    2014-10-01

    To determine whether US home health agencies that intensively engaged with the 2010 Home Health Quality Improvement National Campaign were more likely to reduce acute care hospitalization (ACH) rates than less engaged agencies. We included all Medicare-certified agencies that accessed Campaign resources in the first month of the Campaign and also responded to an online survey of resource utilization at month two. We used the survey data and item response theory to estimate a latent construct we called engagement with the campaign. ACH rates were calculated from the Centers for Medicare & Medicaid Services Outcome and Assessment Information Set for pre- and post-intervention periods (March-November 2009 and 2010, respectively). Staff from 1077 agencies accessed resources in the first month of the Campaign. Of these, 382 provided information about resource use and had 10 or more monthly discharges throughout the measurement periods. Dividing these agencies into quartiles based on engagement score, we found an association between engagement and reduction in ACH rates, P=0.049 (χ(2) for trend). Exploratory path analysis revealed the effect of engagement score on reduction in ACH rate to be partially mediated through reduction in average length of service rates. We found evidence that early intensity of engagement with the Campaign, as measured through use of activities and resources, was positively associated with improvement. To continue the investigation of this relationship, future work in this and other campaigns should focus on further development of engagement measures. © 2014 John Wiley & Sons, Ltd.

  13. Order of 2 March 1984 amending Order of 7 November 1979 on the setting up, within the Atomic Energy Commission, of a National Radioactive Waste Management Agency

    International Nuclear Information System (INIS)

    1984-01-01

    This Order amends the Order of 7th November 1979 concerning the setting up, within the CEA, of a National Radioactive Waste Management Agency (ANDRA). In connection with implementing waste storage operations, ANDRA's role remains unchanged; however, it seemed desirable to further strengthen research, development and assessment in the area of radioactive waste policy. These tasks are included in the CEA's responsibilities and are financed by its research budget. (NEA) [fr

  14. A cysteine protease (cathepsin Z) from disk abalone, Haliotis discus discus: Genomic characterization and transcriptional profiling during bacterial infections.

    Science.gov (United States)

    Godahewa, G I; Perera, N C N; Lee, Sukkyoung; Kim, Myoung-Jin; Lee, Jehee

    2017-09-05

    Cathepsin Z (CTSZ) is lysosomal cysteine protease of the papain superfamily. It participates in the host immune defense via phagocytosis, signal transduction, cell-cell communication, proliferation, and migration of immune cells such as monocytes, macrophages, and dendritic cells. Hence, CTSZ is also acknowledged as an acute-phase protein in host immunity. In this study, we sought to identify the CTSZ homolog from disk abalone (AbCTSZ) and characterize it at the molecular, genomic, and transcriptional levels. AbCTSZ encodes a protein with 318 amino acids and a molecular mass of 36kDa. The structure of AbCTSZ reveals amino acid sequences that are characteristic of the signal sequence, pro-peptide, peptidase-C1 papain family cysteine protease domain, mini-loop, HIP motif, N-linked glycosylation sites, active sites, and conserved Cys residues. A pairwise comparison revealed that AbCTSZ shared the highest amino acid homology with its molluscan counterpart from Crassostrea gigas. A multiple alignment analysis revealed the conservation of functionally crucial elements of AbCTSZ, and a phylogenetic study further confirmed a proximal evolutionary relationship with its invertebrate counterparts. Further, an analysis of AbCTSZ genomic structure revealed seven exons separated by six introns, which differs from that of its vertebrate counterparts. Quantitative real time PCR (qPCR) detected the transcripts of AbCTSZ in early developmental stages and in eight different tissues. Higher levels of AbCTSZ transcripts were found in trochophore, gill, and hemocytes, highlighting its importance in the early development and immunity of disk abalone. In addition, we found that viable bacteria (Vibrio parahaemolyticus and Listeria monocytogenes) and bacterial lipopolysaccharides significantly modulated AbCTSZ transcription. Collectively, these lines of evidences suggest that AbCTSZ plays an indispensable role in the innate immunity of disk abalone. Copyright © 2017. Published by Elsevier

  15. Cathepsin L is an immune-related protein in Pacific abalone (Haliotis discus hannai)--Purification and characterization.

    Science.gov (United States)

    Shen, Jian-Dong; Cai, Qiu-Feng; Yan, Long-Jie; Du, Cui-Hong; Liu, Guang-Ming; Su, Wen-Jin; Ke, Caihuan; Cao, Min-Jie

    2015-12-01

    Cathepsin L, an immune-related protein, was purified from the hepatopancreas of Pacific abalone (Haliotis discus hannai) by ammonium sulfate precipitation and column chromatographies of SP-Sepharose and Sephacryl S-200 HR. Purified cathepsin L appeared as two bands with molecular masses of 28.0 and 28.5 kDa (namely cathepsin La and Lb) on SDS-PAGE under reducing conditions, suggesting that it is a glycoprotein. Peptide mass fingerprinting (PMF) analysis revealed that peptide fragments of 95 amino acid residues was high similarity to cathepsin L of pearl oyster (Pinctada fucata). The optimal temperature and pH of cathepsin L were 35 °C and pH 5.5. Cathepsin L was particularly inhibited by cysteine proteinase inhibitors of E-64 and leupeptin, while it was activated by metalloproteinase inhibitors EDTA and EGTA. The full-length cathepsin L cDNA was further cloned from the hepatopancreas by rapid PCR amplification of cDNA ends (RACE). The open reading frame of the enzyme was 981 bp, encoding 327 amino acid residues, with a conserved catalytic triad (Cys134, His273 and Asn293), a potential N-glycosylation site and conserved ERFNIN, GNYD, and GCGG motifs, which are characteristics of cathepsin L. Western blot and proteinase activity analysis revealed that the expression and enzyme activity of cathepsin L were significantly up-regulated in hepatopancreas at 8 h following Vibrio parahaemolyticus infection, demonstrating that cathepsin L is involved in the innate immune system of abalone. Our present study for the first time reported the purification, characterization, molecular cloning, and tissue expression of cathepsin L in abalone. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Gonadal Transcriptome Analysis of Pacific Abalone Haliotis discus discus: Identification of Genes Involved in Germ Cell Development.

    Science.gov (United States)

    Yu, Lingyun; Xu, Dongdong; Ye, Huan; Yue, Huamei; Ooka, Shioh; Kondo, Hidehiro; Yazawa, Ryosuke; Takeuchi, Yutaka

    2018-04-03

    Little is known about the molecular mechanisms governing gonadal developmental processes in abalones. Here, we conducted transcriptome analysis of Pacific abalone Haliotis discus discus for gene discovery in the brain, ovary, testis, and unfertilized eggs. Among the annotated unigenes, 48.6% of unigenes were identified by Venn diagram analysis as having universal or tissue-specific expression. Twenty-three genes with gonad-biased gene ontology (GO) terms were first obtained. Secondly, 36 genes were found by screening known gene names related to germ cell development. Finally, 17 genes were obtained by querying the annotated unigene database for zygotically expressed gonadal genes (ovary and testis) and maternally expressed gonadal genes (ovary, testis, and unfertilized eggs) using keywords related to reproduction. To further verify tissue distribution pattern and subcellular localization of these genes, RT-PCR and in situ hybridization were performed using a unigene encoding a germ cell marker, vasa, as control. The results showed that vasa was expressed mainly in the early developmental stages of germ cells in both sexes. One of the candidate genes, vitelline envelope zona pellucida domain protein 12 (ZP12), was expressed in the primordial germ cells of immature gonad and early developmental stages of germ cells of the adult female. The results obtained from the present study suggest that vasa and ZP12 are involved in germ cell development of Pacific abalone and that ZP12 is an especially useful germ cell-specific marker in immature adults. The current gonadal transcriptome profile is an extensive resource for future reproductive molecular biology studies of this species.

  17. Recombinant perlucin nucleates the growth of calcium carbonate crystals: molecular cloning and characterization of perlucin from disk abalone, Haliotis discus discus.

    Science.gov (United States)

    Wang, Ning; Lee, Youn-Ho; Lee, Jehee

    2008-02-01

    Perlucin is well known as an important functional protein regulating pearl formation and shell biomineralization. In this study, we cloned the perlucin gene from the abalone Haliotis discus discus cDNA library. The full-length cDNA of the abalone H. discus discus perlucin gene consisted of 1038 bp nucleotides, encoding a putative signal peptide of 22 amino acids and a mature protein of 129 amino acids, which shared 55% identity with the homologous protein in greenlip abalone. The mature protein coding sequence was inserted into pMal-c2X expression vector and it expressed the recombinant protein in E. coli (Rosetta-gammi DE3). The maltose binding protein (MBP) fusion perlucin successfully promoted calcium carbonate precipitation and directed calcite crystal morphological modification. The successful expression of active recombinant perlucin suggested that recombinant perlucin gene transfer has the capability by color modification to improve the pearl's value. In the view of molecular structure, perlucin was a typical C-type lectin, which contained one highly conserved carbohydrate recognition domain. Reverse transcription polymerase chain reaction (RT-PCR) results showed that perlucin gene was expressed not only in the mantle, but also in the gill and digestive tract. Further characterization of perlucin in abalone non-self recognition and disease resistance is promising and anticipated.

  18. Effects of dietary supplementation of probiotic Shewanella colwelliana WA64, Shewanella olleyana WA65 on the innate immunity and disease resistance of abalone, Haliotis discus hannai Ino.

    Science.gov (United States)

    Jiang, Hai-Feng; Liu, Xiao-Lin; Chang, Ya-Qing; Liu, Ming-Tai; Wang, Gao-Xue

    2013-07-01

    The effects of dietary administration of two probiotics, Shewanella colwelliana WA64 and Shewanella olleyana WA65, on the innate immunity of abalone (Haliotis discus hannai Ino), and survival of juvenile abalone challenged with Vibrio harveyi have been studied. Two groups of abalone were fed with three different diets: one control, and two diets supplemented with 10(9) cell g(-1) of probiotic WA64 (WA64 diet) and WA65 (WA65 diet) for up to four weeks. Results showed that abalone fed diets containing S. colwelliana WA64 and S. olleyana WA65 had led to an enhanced cellular and humoral immune response, notably higher haemocytes, respiratory burst activity, serum lysozyme activity and total protein levels were recorded after one week of probiotic administration. On the other hand, mortality after the challenges with V. harveyi in the group fed with control diet ranged from 77 to 80%, while mortality rates observed in the groups fed with diets supplemented with WA64 and WA65 ranged from 27 to 50% and 30-43%, respectively. The results demonstrated potential for S. colwelliana WA64 and S. olleyana WA65 to improve innate immunity and disease resistance in H. discus hannai. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Cascading effects from survival to physiological activities, and gene expression of heat shock protein 90 on the abalone Haliotis discus hannai responding to continuous thermal stress.

    Science.gov (United States)

    Park, Kiyun; Lee, Jung Sick; Kang, Ju-Chan; Kim, Jae Won; Kwak, Ihn-Sil

    2015-02-01

    Increasing temperatures can be a significant stressor for aquatic organisms. Abalones, a type of large marine gastropods, are the most commercially important species in aquaculture for Asia. To evaluate the potential ecological risk posed by temperature stress, we measured biological responses such as survival rate, adhesion ability (falling rate), and foot abnormalities in the abalone Haliotis discus hannai. Additionally, biochemical and molecular responses were evaluated in H. discus hannai exposed to various temperature gradients. The survival rate was reduced in abalones exposed to relative high temperatures (more than 26 °C). Increased temperature stress induced a higher falling rate and abnormal foot structure. Furthermore, increased antioxidant enzyme activities were observed in abalones exposed to relative high temperatures (26 and 28 °C). The activities of superoxide dismutase were induced in a time-dependent manner after high temperature stress. Generally, heat shock protein 90 also increased significantly in H. discus hannai exposed to temperature gradients (more than 24 °C) for 12 h. These results provide valuable information regarding stress responses to increased temperatures, in H. discus hannai: adverse biological and molecular outcomes could be utilized as risk assessments and stress monitoring of marine ecosystems under increased water temperatures. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. [Construction of SSH library from haemocyte of variously colored abalone challenged with bacteria and differential expression analysis of macrophage expressed protein].

    Science.gov (United States)

    Ren, Hong-Lin; Xu, Dan-Dan; Qiao, Kun; Cai, Ling; Huang, Wei-Bin; Zhang, Nai; Wang, Ke-Jian

    2008-08-01

    Abalones are considered to be the most precious delicacy from the sea, and become very important commercial seafood in aquaculture worldwide. Variously colored abalone (Haliotis diversicolor Reeve, 1846) has been widely cultured on the southeast coast for more than twenty years. However, abalone culture frequently suffers from bacterial infection and mass mortality of reared abalones causes serious economic losses. Unfortunately, knowledge of the defense mechanism in this animal is still lacking. In this study, using suppression subtractive hybridization (SSH) technology, a forward SSH library was constructed from haemocytes of H. diversicolor, with the content of 1.37x10(6) pfu and the recombinant rate of 98.18%. After the recombinant plasmids were sequenced, partial cDNA of macrophage expressed protein (MEP) was recognized based on BLAST searches in NCBI, with the size of 1,551 bp, and continuously encoding 517 amino acids. Semi-quantitative PCR and quantitative real-time PCR results showed that MEP cDNA was distinctly up-regulated in haemocytes of the bacterial-challenged group compared to the unchallenged group. The gene information obtained from this library will provide new insights into the immune mechanism of H. diversicolor and facilitate future study of target genes involved in the response to invading microorganisms.

  1. Transforming the Roles of a Public Extension Agency to Strengthen Innovation: Lessons from the National Agricultural Extension Project in Bangladesh

    Science.gov (United States)

    Chowdhury, Ataharul Huq; Odame, Helen Hambly; Leeuwis, Cees

    2014-01-01

    Purpose: The rapidly evolving nature of agricultural innovation processes in low-income countries requires agricultural extension agencies to transform the classical roles that previously supported linear information dissemination and adoption of innovation. In Bangladesh, strengthening agricultural innovation calls for facilitation of interactive…

  2. Tenacibaculum haliotis sp. nov., isolated from the gut of an abalone Haliotis discus hannai.

    Science.gov (United States)

    Kim, Young-Ok; Park, In-Suk; Park, Sooyeon; Nam, Bo-Hye; Park, Ji-Min; Kim, Dong-Gyun; Yoon, Jung-Hoon

    2017-09-01

    A Gram-stain-negative, non-flagellated, gliding, non-spore-forming bacterial strain, designated RA3-2T, was isolated from the gut of an abalone (Haliotis discus hannai) collected from the sea around Jeju island, South Korea, and subjected to a polyphasic taxonomic study. RA3-2T grew optimally at 20 °C and in the presence of 2.0-3.0 % (w/v) NaCl. Phylogenetic trees based on 16S rRNA gene sequences indicated that RA3-2T fell within the clade comprising the type strains of species of the genus Tenacibaculum, clustering with the type strains of Tenacibaculum soleae, Tenacibaculum ovolyticum and Tenacibaculum dicentrarchi; showing 16S rRNA gene sequence similarity values of 96.2-96.8 %. The novel strain exhibited 16S rRNA gene sequence similarity values of 93.5-96.9 % to the type strains of the other species of the genus Tenacibaculum. RA3-2T contained MK-6 as the predominant menaquinone and iso-C15 : 0 and iso-C15 : 0 3-OH as the major fatty acids. The major polar lipids of RA3-2T were phosphatidylethanolamine, two unidentified lipids, one unidentified aminophospholipid and one unidentified glycolipid. The DNA G+C content of RA3-2T was 31.7 mol%. The differential phenotypic properties, together with the phylogenetic data, revealed that RA3-2T is separated from other species of the genus Tenacibaculum with validly published names. On the basis of the data presented, RA3-2T is considered to represent a novel species of the genus Tenacibaculum, for which the name Tenacibaculum haliotis sp. nov. is proposed. The type strain is RA3-2T (=KCTC 52419T=NBRC 112382T).

  3. Exploring Spatiotemporal Trends in Commercial Fishing Effort of an Abalone Fishing Zone: A GIS-Based Hotspot Model.

    Directory of Open Access Journals (Sweden)

    M Ali Jalali

    Full Text Available Assessing patterns of fisheries activity at a scale related to resource exploitation has received particular attention in recent times. However, acquiring data about the distribution and spatiotemporal allocation of catch and fishing effort in small scale benthic fisheries remains challenging. Here, we used GIS-based spatio-statistical models to investigate the footprint of commercial diving events on blacklip abalone (Haliotis rubra stocks along the south-west coast of Victoria, Australia from 2008 to 2011. Using abalone catch data matched with GPS location we found catch per unit of fishing effort (CPUE was not uniformly spatially and temporally distributed across the study area. Spatial autocorrelation and hotspot analysis revealed significant spatiotemporal clusters of CPUE (with distance thresholds of 100's of meters among years, indicating the presence of CPUE hotspots focused on specific reefs. Cumulative hotspot maps indicated that certain reef complexes were consistently targeted across years but with varying intensity, however often a relatively small proportion of the full reef extent was targeted. Integrating CPUE with remotely-sensed light detection and ranging (LiDAR derived bathymetry data using generalized additive mixed model corroborated that fishing pressure primarily coincided with shallow, rugose and complex components of reef structures. This study demonstrates that a geospatial approach is efficient in detecting patterns and trends in commercial fishing effort and its association with seafloor characteristics.

  4. Habitat Preferences of Juvenile Abalone (Haliotis mariae Wood, 1828 Along the Dhofar Coast of Oman and Implications for Conservation

    Directory of Open Access Journals (Sweden)

    Schalk Willem Petrus de Waal

    2012-01-01

    Full Text Available Surveys were conducted along the eastern Dhofar coast of Oman to investigate densities and habitat preferences of juvenile Haliotis mariae ( 50 cm Ø, respectively. B values were highest for urchins (6 times that for small boulders, and for boulders <50 cm Ø. B values for boulder habitats decreased as boulder size increased. Urchin utilisation by juvenile abalone as shelter ranged between geographic areas from a minimum of 15.5% to a maximum of 47.6%. The proportion of total habitat that is preferred by more than 97% of juvenile abalone found, including urchins and boulders < 50 cm Ø, comprises 29% of surveyed substratum. While the role urchins play on wild juvenile H. mariae has not proved vital, it is definitely significant. Although juvenile densities are low and are not currently limited by the availability of suitable habitat, it is crucial to identify and conserve those microhabitats that support recruitment of H. mariae. The abundance of these areas should be among the criteria used in selecting protected conservation areas.

  5. Tumor suppressor QM-like gene from disk abalone (Haliotis discus discus): molecular characterization and transcriptional analysis upon immune challenge.

    Science.gov (United States)

    Oh, Chulhong; De Zoysa, Mahanama; Nikapitiya, Chamilani; Whang, Ilson; Kim, Yu Cheol; Kang, Do-Hyung; Heo, Soo-jin; Choi, Young-Ung; Choi, Cheol Young; Lee, Jae-Seong; Lee, Jehee

    2010-09-01

    We describe molecular characterization and transcriptional analysis of the gene encoding tumor suppressor QM-like protein, AbQM, in the disk abalone Haliotis discus discus. The full-length cDNA (765-bp) of AbQM was found to consist of a 654-bp ORF coding for a 218 amino acid protein of a 25 kDa molecular mass with a 10.2 isoelectric point. Analysis of AbQM sequence revealed the presence of characteristic motifs, including the ribosomal protein L10 signature, SH3-binding motif and two antibiotic binding sites. Phylogenetic analysis confirmed that AbQM is closely related to other mollusk QM proteins, and altogether they form a mollusk QM protein sub-family which displays evolutionary conservation from yeast to human. Tissue-specific expression and transcriptional regulation of AbQM was analyzed by quantitative real-time PCR in response to bacterial (Vibrio alginolyticus and Vibrio parahemolyticus, Listeria monocytogenes) and viral (viral hemorrhagic septicemia virus, VHSV) challenge. AbQM transcripts were found to be expressed ubiquitously in all examined tissues in a constitutive manner, as similar expression levels were detected in hemocytes, mantle, digestive tract and muscle. Upon bacterial and VHSV challenge, AbQM showed significant up-regulation in gills, but not in hemocytes. Taken together, these findings suggest that AbQM in abalone-like mollusks can respond to and facilitate a defensive effect against pathogenic infection. Copyright 2010 Elsevier Ltd. All rights reserved.

  6. Seasonal and algal diet-driven patterns of the digestive microbiota of the European abalone Haliotis tuberculata, a generalist marine herbivore.

    Science.gov (United States)

    Gobet, Angélique; Mest, Laëtitia; Perennou, Morgan; Dittami, Simon M; Caralp, Claire; Coulombet, Céline; Huchette, Sylvain; Roussel, Sabine; Michel, Gurvan; Leblanc, Catherine

    2018-03-27

    Holobionts have a digestive microbiota with catabolic abilities allowing the degradation of complex dietary compounds for the host. In terrestrial herbivores, the digestive microbiota is known to degrade complex polysaccharides from land plants while in marine herbivores, the digestive microbiota is poorly characterized. Most of the latter are generalists and consume red, green, and brown macroalgae, three distinct lineages characterized by a specific composition in complex polysaccharides, which represent half of their biomass. Subsequently, each macroalga features a specific epiphytic microbiota, and the digestive microbiota of marine herbivores is expected to vary with a monospecific algal diet. We investigated the effect of four monospecific diets (Palmaria palmata, Ulva lactuca, Saccharina latissima, Laminaria digitata) on the composition and specificity of the digestive microbiota of a generalist marine herbivore, the abalone, farmed in a temperate coastal area over a year. The microbiota from the abalone digestive gland was sampled every 2 months and explored using metabarcoding. Diversity and multivariate analyses showed that patterns of the microbiota were significantly linked to seasonal variations of contextual parameters but not directly to a specific algal diet. Three core genera: Psychrilyobacter, Mycoplasma, and Vibrio constantly dominated the microbiota in the abalone digestive gland. Additionally, a less abundant and diet-specific core microbiota featured genera representing aerobic primary degraders of algal polysaccharides. This study highlights the establishment of a persistent core microbiota in the digestive gland of the abalone since its juvenile state and the presence of a less abundant and diet-specific core community. While composed of different microbial taxa compared to terrestrial herbivores, the digestive gland constitutes a particular niche in the abalone holobiont, where bacteria (i) may cooperate to degrade algal polysaccharides to

  7. 76 FR 9578 - National Center for Environmental Health/Agency for Toxic Substances and Disease Registry (NCEH...

    Science.gov (United States)

    2011-02-18

    ... National Conversation on Public Health and Chemical Exposures Leadership Council Meeting Time and Date: 8... Conversation on Public Health and Chemical Exposures Leadership Council. The National Conversation on Public... public's health from harmful chemical exposures. The Leadership Council provides overall guidance to the...

  8. Order of 7 November 1979 creating a National Radioactive Waste Management Agency within the Atomic Energy Commission

    International Nuclear Information System (INIS)

    1979-01-01

    The new Agency set up by this Decree succeeds the CEA Waste Management Bureau. It is responsible for long-term radioactive waste management operations and, in particular, the management of long-term waste repositories either directly or through third parties acting on its behalf. It is also in charge of designing and setting-up new long-term waste repositories, of preparing in consultation with waste producers, specifications for waste storage and conditioning prior to disposal, of contributing to research and work on long-term waste management processes. The Agency will be consulted on R and D programmes as well as on draft regulations on radioactive waste management. (NEA) [fr

  9. The U.S. Agency-Level Bid Protest Mechanism: A Model for Bid Challenge Procedures in Developing Nations

    National Research Council Canada - National Science Library

    Troff, Erik A

    2005-01-01

    ... comply with established procurement rules. The decisive question for a developing nation is which of the available structural options best integrates the essential elements of an effective bid protest system in the context of existing legal...

  10. Methodology applied by the Petroleum, Natural Gas and Bio fuels National Agency for detection of cartels - their limits and perspectives; Metodology adotada pela Agencia Nacional do Petroleo, Gas Natural e Biocombustiveis para detectecao de carteis - seus limites e perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Pedra, Douglas Pereira; Sales, Orlando de Araujo Vilela; Baran, Patricia Huguenin; Paiva, Rodrigo Milao de [Agencia Nacional do Petroleo, Gas Natural e Biocombustiveis (ANP), Rio de Janeiro, RJ (Brazil). Regulacao de Petroleo, seus Derivados, Alcool Combustivel e Gas Natural; Bicalho, Lucia Maria de Oliveira Navegantes [Universidade Federal do Rio de Janeiro (PPE/COPPE/UFRJ), RJ (Brazil). Coordenacao dos Programas de Pos-Graduacao de Engenharia. Programa de Planejamento Energetico

    2010-07-01

    This paper presents the present methodology used by the Defense Competition Coordination of the Petroleum National Agency for detection of vestiges of cartels in the Brazilian fuel market, their limits, in view of the instruments presently at the disposal of the Agency and perspectives of modification from the eventual availability of new instruments.

  11. GI+100: Long Term Preservation of Digital Geographic Information - 16 Fundamental Principles Agreed by National Mapping Agencies and State Archives

    Directory of Open Access Journals (Sweden)

    Carsten Carsten Rönsdorf

    2017-05-01

    There are many reasons why people wish to retain access to information, though the main drivers for archiving digital geographic information include meeting legislative requirements; the short and long term exploitation of archived data for analyzing social, environmental (e.g. global climate changes and economic changes over time; as well as efficiency savings in managing superseded datasets. This paper sets out the path and describes what needs to be done now to future-proof the investment government agencies around the world have made in creating digital geographic data.

  12. U.S. Environmental Protection Agency national network of research centers: A case study in socio-political influences on research

    Energy Technology Data Exchange (ETDEWEB)

    Morehouse, K. [Environmental Protection Agency, Washington, DC (United States)

    1995-12-01

    During the 15 years that the U.S. Environmental Protection Agency (EPA) has supported university-based research centers, there have been many changes in mission, operating style, funding level, eligibility, and selection process. Even the definition of the term {open_quotes}research center{close_quotes} is open to debate. Shifting national priorities, political realities, and funding uncertainties have powered the evolution of research centers in EPA, although the agency`s basic philosophy on the purpose and value of this approach to research remains essentially unchanged. Today, EPA manages 28 centers, through the Office of Exploratory Research. These centers are administered under three distinct programs. Each program has its own mission and goals which guide the way individual centers are selected and operated. This paper will describe: (1) EPA`s philosophy of reserach centers, (2) the complicated history of EPA research centers, (3) coordination and interaction among EPA centers and others, (4) opportunities for collaboration, and (5) plans for the future.

  13. A Thailand case study based on quantitative assessment: does a national lead agency make a difference in pre-hospital care development in middle income countries?

    Science.gov (United States)

    Suriyawongpaisal, Paibul; Aekplakorn, Wichai; Tansirisithikul, Rassamee

    2014-12-12

    Emergency Medical Institute of Thailand (EMIT) has been established as a national lead agency to improve emergency medical service systems since December 2008. However up to now, there has not been any published systematic assessment of its performance to guide further policy decisions. This study assesses the 4-year pre-hospital care coverage and performance in Thailand after EMIT establishment. The assessment makes use of 1,171,564 records from a national data set for pre-hospital care i.e., Information Technology for Emergency Medical Service System (ITEMS) in 2012. Comparing with historical data, we found evidence indicating the national lead agency making differences in two basic requirements of pre-hospital care i.e., the coverage was increased by at least 1.4 times higher than the majority reported figures among 11 out of the total 13 regions of the country at baseline; and mean total response time for critical-coded patients, the longest in our study, is 1.6 times shorter than previously reported figure in 2008 (48.46 minutes). Analysis of the national data set also revealed quite substantial missing values indicating a need for further improvement. When historical data was not available, we compared our findings with international figures. Over triage rate of 28.4% for advanced life support (ALS) ambulance was found which is roughly a third of that reported in Taiwan. Almost all patients were stabilized and/or treated regardless of being transferred to hospitals in contrast to the scenarios in the U.S. systems which may probably be due to different payment mechanism. Relying on circumstantial evidences, we identified probable stagnation in pre-hospital care coverage for patients visiting emergency department after the establishment of the lead agency. This national data assessment shows progression in certain basic pre-hospital care requirements in Thailand. However, it needs regular systematic evaluation and there is still room for improvement of pre

  14. Physiological performance of juvenile Haliotis rufescens and Haliotis discus hannai abalone exposed to the withering syndrome agent.

    Science.gov (United States)

    González, Roxana C; Brokordt, Katherina; Lohrmann, Karin B

    2012-09-15

    Withering syndrome (WS) is a serious chronic disease caused by infection with the bacterium Candidatus Xenohaliotis californiensis, a Rickettsiales-like organism (WS-RLO) that affects multiple abalone species in both natural and farmed populations. However, there is no available information regarding the effects of this disease on the physiological performance of infected abalone. We studied the effect of different levels of infection on components of energy balance and physiological indices (rates of absorption and assimilation, O/N ratio, and scope for growth) in the abalone species Haliotis rufescens and Haliotis discus hannai. Juveniles were exposed to C. X. californiensis transmission for 130 days, during which time the presence/absence of WS-RLOs was evaluated by PCR (following DNA sequencing-based confirmation of 100% identity with the sequence of C. X. californiensis from California), and the prevalence and intensity of infection were evaluated via histological analysis. Among H. rufescens juveniles exposed to the bacterium, 92% became infected (positive by histology), and the intensity of infection ranged from low (degree 1) to moderate (degree 2). In contrast, no H. discus hannai juveniles were positive for WS-RLO by histology, although 23% were positive by PCR, possibly indicating incipient WS-RLO infection that did not develop during the experimental period or to mere presence of WS-RLO DNA in the sample. Infection of H. rufescens juveniles by WS-RLOs negatively affected all components of the energy balance and physiological indices, such as scope for growth and the O/N ratio, in direct relation to the degree of infection. The most strongly affected functions were the rate of ingestion, standard metabolism, and production of feces, which were reduced by 60-80% in the most highly infected individuals. The reduced energy intake in the organisms produced a strong energy imbalance such that the energy available for growth was reduced by 49% in infected

  15. Polaribacter haliotis sp. nov., isolated from the gut of abalone Haliotis discus hannai.

    Science.gov (United States)

    Kim, Young-Ok; Park, In-Suk; Park, Sooyeon; Nam, Bo-Hye; Park, Ji-Min; Kim, Dong-Gyun; Yoon, Jung-Hoon

    2016-12-01

    A Gram-stain-negative, aerobic, non-motile and coccoid, ovoid or rod-shaped bacterial strain, designated RA4-7T, was isolated from the gut of an abalone (Haliotis discus hannai) collected from the sea around Jeju island, South Korea, and subjected to a polyphasic taxonomic study. RA4-7T grew optimally at 25 °C, at pH 7.0-7.5 and in the presence of 2.0-3.0 % (w/v) NaCl. The phylogenetic trees based on 16S rRNA gene sequences showed that RA4-7T represented a member of the genus Polaribacter. RA4-7T exhibited 16S rRNA gene sequence similarity values of 97.64 and 97.23 % to Polaribacter atrinae WP25T and Polaribacter dokdonensis DSW-5T, respectively, and of 93.83-96.99 % to the type strains of the other species of the genus Polaribacter. RA4-7T contained MK-6 as the predominant menaquinone and summed feature 3 (C16 : 1ω7c and/or C16 : 1ω6c), iso-C15 : 0 3-OH and iso-C15 : 0as the major fatty acids. The major polar lipids detected in RA4-7T were phosphatidylethanolamine and one unidentified lipid. The DNA G+C content of RA4-7T was 30.5 mol% and its DNA-DNA relatedness values with the type strains of P. atrinae and P. dokdonensis were 16 and 11 %, respectively. Differential phenotypic properties, in combination with its phylogenetic and genetic distinctiveness, revealed that RA4-7T is separated from species of the genus Polaribacter with validly published names. On the basis of the data presented, RA4-7T represented a novel species of the genus Polaribacter, for which the name Polaribacterhaliotis sp. nov. is proposed. The type strain is RA4-7T (=KCTC 52418T=NBRC 112383T).

  16. Effects of ocean acidification with pCO2diurnal fluctuations on survival and larval shell formation of Ezo abalone, Haliotis discus hannai.

    Science.gov (United States)

    Onitsuka, Toshihiro; Takami, Hideki; Muraoka, Daisuke; Matsumoto, Yukio; Nakatsubo, Ayumi; Kimura, Ryo; Ono, Tsuneo; Nojiri, Yukihiro

    2018-03-01

    This study assessed the effects of constant and diurnally fluctuating pCO 2 on development and shell formation of larval abalone Haliotis discus hannai. The larvae was exposed to different pCO 2 conditions; constant [450, 800, or 1200 μatm in the first experiment (Exp. I), 450 or 780 μatm in the second experiment (Exp. II)] or diurnally fluctuating pCO 2 (800 ± 400 or 1200 ± 400 μatm in Exp. I, 450 ± 80, 780 ± 200 or 780 ± 400 μatm in Exp. II). Mortality, malformation rates or shell length of larval abalone were not significantly different among the 450, 800, and 800 ± 400 μatm pCO 2 treatments. Meanwhile, significantly higher malformation rates and smaller shells were detected in the 1200 and 1200 ± 400 μatm pCO 2 treatments than in the 450 μatm pCO 2 treatment. The negative impacts were greater in the 1200 ± 400 μatm than in the 1200 μatm. Shell length and malformation rate of larval abalone were related with aragonite saturation state (Ω-aragonite) in experimental seawater, and greatly changed around 1.1 of Ω-aragonite which corresponded to 1000-1300 μatm pCO 2 . These results indicate that there is a pCO 2 threshold associated with Ω-aragonite in the seawater, and that pCO 2 fluctuations produce additional negative impacts on abalone when above the threshold. Clear relationships were detected between abalone fitness and the integrated pCO 2 value over the threshold, indicating that the effects of OA on development and shell formation of larval abalone can be determined by intensity and time of exposure to pCO 2 over the threshold. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Confined to a tokenistic status: Social scientists in leadership roles in a national health research funding agency.

    Science.gov (United States)

    Albert, Mathieu; Laberge, Suzanne

    2017-07-01

    The idea of interdisciplinarity has been taken up by academic and governmental organisations around the world and enacted through science policies, funding programs and higher education institutions. In Canada, interdisciplinarity led to a major transformation in health research funding. In 2000, the federal government closed the Medical Research Council (MRC) and created the Canadian Institutes of Health Research (CIHR). From the outset, CIHR's vision and goals were innovative, as it sought to include the social sciences within its purview alongside more traditional health research sectors. The extent to which it has been successful in this endeavour, however, remains unknown. The aim of our study was to examine how CIHR's intentions to foster inclusiveness and cooperation across disciplines were implemented in the agency's own organisational structure. We focused on social scientists' representation on committees and among decision-makers between 2000 and 2015, one of the key mandates of CIHR being to include the social sciences within its remit and support research in this area. We examined the composition of the Governing Council, the Institute Scientific Directors, the Chairs of the College of Reviewers, and two International Review Panels invited by CIHR. We targeted these committees and decision-makers since they hold the power to influence the field of Canadian health research through the decisions they make. Our findings show that, while CIHR was created with the mandate to support the entire spectrum of health-related research-including the social sciences-this call for inclusiveness has not yet been materialized in the agency's organisational structure. Social scientists, as well as researchers from neighbouring disciplines such as social epidemiology, health promotion and the humanities, are still confined to low levels of representation within CIHR's highest echelons. This imbalance limits social scientists' input into health research in Canada and

  18. Act No. 61 of 21 January 1994-Transformation into law, with amendments, of Decree-Law No. 496 of 4 December 1996 laying down urgent provisions on reorganising environmental controls and creating the National Environmental Protection Agency

    International Nuclear Information System (INIS)

    1994-01-01

    This Act sets up the National Environmental Protection Agency-ANPA which replaces the Nuclear Safety and Health Protection Directorate (ENEA/DISP) of the National Agency for New Technology, Energy and the Environment (ENEA). The ENEA/DISP's tasks, staff, structures, technical equipment and financial resources are transferred to the new Agency. ANPA is responsible for all the national technical and scientific activities and co-ordinates the working methods of the above-mentioned regional and provincial agencies. It also provides consultation and support services to the Ministry of the environment. In particular, ANPA is competent for supervising activities related to the peaceful uses of nuclear energy and analysing the impact of radiation on the environment. (NEA)

  19. iTRAQ-Based Identification of Proteins Related to Muscle Growth in the Pacific Abalone, Haliotis discus hannai.

    Science.gov (United States)

    Huang, Jianfang; You, Weiwei; Luo, Xuan; Ke, Caihuan

    2017-10-25

    The abalone Haliotis discus hannai is an important aquaculture species that is grown for human consumption. However, little is known of the genetic mechanisms governing muscle growth in this species, particularly with respect to proteomics. The isobaric tag for relative and absolute quantitation (iTRAQ) method allows for sensitive and accurate protein quantification. Our study was the first to use iTRAQ-based quantitative proteomics to investigate muscle growth regulation in H. discus hannai . Among the 1904 proteins identified from six samples, 125 proteins were differentially expressed in large specimens of H. discus hannai as compared to small specimens. In the large specimens, 47 proteins were upregulated and 78 were downregulated. Many of the significant Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, including these differentially expressed proteins, were closely related to muscle growth, including apoptosis, thyroid hormone signaling, regulation of the actin cytoskeleton, and viral myocarditis ( p discus hannai .

  20. Marine reserves help preserve genetic diversity after impacts derived from climate variability: Lessons from the pink abalone in Baja California

    Directory of Open Access Journals (Sweden)

    Adrián Munguía-Vega

    2015-07-01

    Full Text Available Genetic diversity is crucial for the adaptation of exploited species like the pink abalone (Haliotis corrugata, faced with threats from climate change, overfishing and impacts associated with aquaculture production. While marine reserves are commonly used to mitigate risks to marine populations, the duration, size, location and larval connectivity needed for a reserve to help conserve genetic resources is still poorly understood. Here, we examine the effects of fishing, reserves, and restocking on the genetic diversity of 10 populations from central Baja California, Mexico, and Southern California, USA. We demonstrate that each population shows characteristic genetic signatures according to recent management decisions. We found high allelic diversity, particularly rare alleles, a larger effective population size and a lack of a recent genetic bottleneck in pink abalones within a small (0.8 km2, recently established (5 years reserve in Baja California, compared to other fished sites after a climatic bottleneck. Higher diversity may result from the presence of older animals in the reserve. Due to its location, the reserve may also act as an important hub connecting distant populations via larval dispersal. In contrast, a population from California showed genetic isolation, loss of allelic diversity and high relatedness, consistent with the collapse of fisheries in the 1990s and their lack of recovery thereafter. In addition, a fished area in Baja California with a history of restocking for over a decade showed an increase in frequency of related individuals and high genetic differentiation from nearby sites that were consistent with the production of larvae from a few adults in the laboratory. A network of strategically placed small marine reserves that considers ocean circulation patterns could help to maintain genetic diversity and connectivity of exploited populations.

  1. Kazal-type proteinase inhibitor from disk abalone (Haliotis discus discus): molecular characterization and transcriptional response upon immune stimulation.

    Science.gov (United States)

    Wickramaarachchi, W D Niroshana; De Zoysa, Mahanama; Whang, Ilson; Wan, Qiang; Lee, Jehee

    2013-09-01

    Proteinases and proteinase inhibitors are involved in several biological and physiological processes in all multicellular organisms. Proteinase inhibitors play a key role in regulating the activity of the respective proteinases. Among serine proteinase inhibitors, kazal-type proteinase inhibitors (KPIs) are widely found in mammals, avians, and a variety of invertebrates. In this study, we describe the identification of a kazal-type serine proteinase inhibitor (Ab-KPI) from the disk abalone, Haliotis discus discus, which is presumably involved in innate immunity. The full-length cDNA of Ab-KPI includes 600 bp nucleotides with an open reading frame (ORF) encoding a polypeptide of 143 amino acids. The deduced amino acid sequence of Ab-KPI contains a putative 17-amino acid signal peptide and two tandem kazal domains with high similarity to other kazal-type SPIs. Each kazal domain consists of reactive site (P1) residue containing a leucine (L), and a threonine (T) located in the second amino acid position after the second conserved cysteine of each domain. Temporal expression of Ab-KPI was assessed by real time quantitative PCR in hemocytes and mantle tissue following bacterial and viral hemorrhagic septicemia virus (VHSV) challenge, and tissue injury. At 6 h post-bacterial and -VHSV challenge, Ab-KPI expression in hemocytes was increased 14-fold and 4-fold, respectively, compared to control samples. The highest up-regulations upon tissue injury were shown at 9 h and 12 h in hemocytes and mantle, respectively. The transcriptional modulation of Ab-KPI following bacterial and viral challenges and tissue injury indicates that it might be involved in immune defense as well as wound healing process in abalone. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Ferritin from the Pacific abalone Haliotis discus hannai: Analysis of cDNA sequence, expression, and activity.

    Science.gov (United States)

    Qiu, Reng; Kan, Yunchao; Li, Dandan

    2016-02-01

    Ferritin plays an important role in iron homeostasis due to its ability to bind and sequester large amounts of iron. In this study, the gene encoding a ferritin (HdhFer2) was cloned from Pacific abalone (Haliotis discus hannai). The full-length cDNA of HdhFer2 contains a 5'-UTR of 121 bp, an ORF of 516 bp, and a 3'-UTR of 252 bp with a polyadenylation signal sequence of AATAAA and a poly(A) tail. It also contains a 31 bp iron-responsive element (IRE) in the 5'-UTR position, which is conserved in many ferritins. HdhFer2 consists of 171 amino acid residues with a predicted molecular weight (MW) ∼19.8 kDa and a theoretical isoelectric point (PI) of 4.84. The deduced amino acid sequence of HdhFer2 contains two ferritin iron-binding region signatures (IBRSs). HdhFer2 mRNA was detected in a wide range of tissues and was dominantly expressed in the gill. Infection with the bacterial pathogen Vibrio anguillarum significantly upregulated HdhFer2 expression in a time-dependent manner. Recombinant HdhFer2 (rHdhFer2) purified from Escherichia coli was able to bind ferrous iron in a concentration-dependent manner. In summary, these results suggest that HdhFer2 is a crucial protein in the iron-withholding defense system, and plays an important role in the innate immune response of abalone. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Molluskan fasciclin-1 domain-containing protein: molecular characterizationand gene expression analysis of fasciclin 1-like protein from disk abalone (Haliotis discus discus).

    Science.gov (United States)

    Premachandra, H K A; De Zoysa, Mahanama; Nikapitiya, Chamilani; Lee, Youngdeuk; Wickramaarachchi, W D N; Whang, Ilson; Lee, Jehee

    2013-06-15

    Cell-to-cell contacts play a key role in multicellular systems and organisms. Fasciclin-1 (FAS-1) is a lipid-linked membrane associated glycoprotein that is a member of a newly recognized family of cell adhesion molecules sharing features with the immunoglobulins, cadherins, integrins, and selectins. Here, we report the identification and molecular characterization of a novel FAS-1 domain-containing cDNA from disk abalone (Haliotis discus discus), including its gene expression profile and immune response to bacterial stimuli and tissue injuries. Designated as Abfac1, the 909bp open reading frame (ORF) encodes 303 amino acid (aa) residues with a predicted molecular mass of 33kDa and isoelectric (pI) value of 4.9. The aa sequence contains two FAS-1 domains and three conserved regions, FRa motif, H-box, and FRb motif. Phylogenetic analysis showed the closest relation to Jellyfish cell adhesion protein. In healthy abalone, Abfac1 expression is highest in hepatopancreas followed by mantle and lowest in digestive gland. In immune-stimulated abalones, relative Abfac1 mRNA expression was increased in hemocytes by ~11-fold at 48h after the Vibrio parahaemolyticus infection, by 3.1-fold at 6h after the Listeria monocytogenes infection and by ~9-fold at 6h after the LPS injection. Similarly, tissue injuries caused significant increase of relative mRNA expression by 3.5-fold in hemocytes and by ~10-fold in mantle at 12h post-injury. These results suggest that the novel member of the FAS-1 domain-containing protein family, Abfac1, may be involved in immune response and cell adhesion in disk abalone. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Structural and functional characterization of a novel molluskan ortholog of TRAF and TNF receptor-associated protein from disk abalone (Haliotis discus discus).

    Science.gov (United States)

    Lee, Youngdeuk; Elvitigala, Don Anushka Sandaruwan; Whang, Ilson; Lee, Sukkyoung; Kim, Hyowon; Zoysa, Mahanama De; Oh, Chulhong; Kang, Do-Hyung; Lee, Jehee

    2014-09-01

    Immune signaling cascades have an indispensable role in the host defense of almost all the organisms. Tumor necrosis factor (TNF) signaling is considered as a prominent signaling pathway in vertebrate as well as invertebrate species. Within the signaling cascade, TNF receptor-associated factor (TRAF) and TNF receptor-associated protein (TTRAP) has been shown to have a crucial role in the modulation of immune signaling in animals. Here, we attempted to characterize a novel molluskan ortholog of TTRAP (AbTTRAP) from disk abalone (Haliotis discus discus) and analyzed its expression levels under pathogenic stress. The complete coding sequence of AbTTRAP consisted of 1071 nucleotides, coding for a 357 amino acid peptide, with a predicted molecular mass of 40 kDa. According to our in-silico analysis, AbTTRAP resembled the typical TTRAP domain architecture, including a 5'-tyrosyl DNA phosphodiesterase domain. Moreover, phylogenetic analysis revealed its common ancestral invertebrate origin, where AbTTRAP was clustered with molluskan counterparts. Quantitative real time PCR showed universally distributed expression of AbTTRAP in selected tissues of abalone, from which more prominent expression was detected in hemocytes. Upon stimulation with two pathogen-derived mitogens, lipopolysaccharide (LPS) and polyinosinic:polycytidylic acid (poly I:C), transcript levels of AbTTRAP in hemocytes and gill tissues were differentially modulated with time. In addition, the recombinant protein of AbTTRAP exhibited prominent endonuclease activity against abalone genomic DNA, which was enhanced by the presence of Mg(2+) in the medium. Collectively, these results reinforce the existence of the TNF signaling cascade in mollusks like disk abalone, further implicating the putative regulatory behavior of TTRAP in invertebrate host pathology. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Effect of air-temperature and diet composition on the drying process of pellets for japanese abalone (Haliotis discus hannai) feeding

    OpenAIRE

    Vega-Gálvez, Antonio; Lemus-Mondaca, Roberto; Plaza-Sáez, Daniel; Pérez-Won, Mario

    2011-01-01

    The aim of this research was to study the effect of air-temperature and diet composition on the mass transfer kinetics during the drying process of pellets used for Japanese Abalone (Haliotis discus hannai) feeding. In the experimental design, three temperatures were used for convective drying, as well as three different diet compositions (Diets A, B and C), in which the amount of fishmeal, spirulin, algae, fish oil and cornstarch varied. The water diffusion coefficient of the pellets was det...

  6. Agency IP Data

    Data.gov (United States)

    National Aeronautics and Space Administration — Public data set for NASA Agency Intellectual Property (IP). The distribution contains both Patent information as well as General Release of Open Source Software.

  7. Methodology for developing evidence-based clinical imaging guidelines: Joint recommendations by Korea society of radiology and national evidence-based healthcare collaborating agency

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Sol Ji; Jo, Ae Jeong; Choi, Jin A [Div. for Healthcare Technology Assessment Research, National Evidence-Based Healthcare Collaborating Agency, Seoul (Korea, Republic of); and others

    2017-01-15

    This paper is a summary of the methodology including protocol used to develop evidence-based clinical imaging guidelines (CIGs) in Korea, led by the Korean Society of Radiology and the National Evidence-based Healthcare Collaborating Agency. This is the first protocol to reflect the process of developing diagnostic guidelines in Korea. The development protocol is largely divided into the following sections: set-up, process of adaptation, and finalization. The working group is composed of clinical imaging experts, and the developmental committee is composed of multidisciplinary experts to validate the methodology. The Korean CIGs will continue to develop based on this protocol, and these guidelines will act for decision supporting tools for clinicians as well as reduce medical radiation exposure.

  8. The feasibility of bomb radiocarbon analysis to support an age-at-length relationship for red abalone, Haliotis rufescens Swainson in northern California

    Energy Technology Data Exchange (ETDEWEB)

    Leaf, R T; Andrews, A H; Cailliet, G M; Brown, T A

    2009-01-07

    Analysis of bomb generated radiocarbon ({sup 14}C) changes in a red abalone, Haliotis rufescens Swainson shell was used to investigate age-at-length relationships derived from data from a previous multi-year, multi-site tag-recapture study. Shell carbonate was extracted from four successive growth trajectory locations in a single shell with a length of 251 mm MSL. Extraction locations were based on VBGF predictions and chosen to span the initial rise of the {sup 14}C-bomb pulse that is known to have occurred in surface ocean waters during 1958 {+-} 1 y in the northeast Pacific. The close temporal correspondence of the red abalone sample series to regional {Delta}{sup 14}C records demonstrated the utility of the technique for validating age-at-length relationships for the red abalone. The findings provided support for a mean VBGF derived age of 32 y (range 30 to 33 y) for the specimen; however, the analysis of {sup 14}C data indicated that the specimen could be older.

  9. Molecular insights of the first gastropod TLR counterpart from disk abalone (Haliotis discus discus), revealing its transcriptional modulation under pathogenic stress.

    Science.gov (United States)

    Elvitigala, Don Anushka Sandaruwan; Premachandra, H K A; Whang, Ilson; Nam, Bo-Hye; Lee, Jehee

    2013-08-01

    Toll-like receptors (TLRs) are well-characterized pattern recognition receptors of innate immunity, known to induce immune responses against the pathogens by interacting with evolutionarily conserved pathogen-associated molecular patterns (PAMPs). In this study, a novel TLR homolog from disk abalone (Haliotis discus discus) was identified and characterized at molecular level. The open reading frame (ORF) of AbTLR is 3804 bp in length and encodes a 1268 amino acid peptide with a calculated molecular mass of 143.5 kDa. The deduced protein shows typical TLR domain architecture, with leucine rich repeats (LRR) and the toll-interleukin receptor (TIR) domain. Phylogenetic analysis revealed a close evolutionary relationship for AbTLR to its invertebrate counterparts, with close clustering to the molluscan homologs. Quantitative real-time PCR detected ubiquitous transcription of AbTLR in healthy tissues, but with highest levels in hemocytes. Differential transcriptional modulation of AbTLR was observed in abalone hemocytes and gills upon immune challenge, whereby Vibrio parahaemolyticus and purified lipopolysaccharide (LPS) enhanced the transcript level prominently. In addition, the viral hemorrhagic septicemia virus induced AbTLR transcription in hemocytes and gills, representing the first evidence of viral-induced immune response in mollusks to date. Collectively, our findings support a putative role for AbTLR in abalone antiviral and antibacterial defense. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Transcriptome-Wide Single Nucleotide Polymorphisms (SNPs for Abalone (Haliotis midae: Validation and Application Using GoldenGate Medium-Throughput Genotyping Assays

    Directory of Open Access Journals (Sweden)

    Rouvay Roodt-Wilding

    2013-09-01

    Full Text Available Haliotis midae is one of the most valuable commercial abalone species in the world, but is highly vulnerable, due to exploitation, habitat destruction and predation. In order to preserve wild and cultured stocks, genetic management and improvement of the species has become crucial. Fundamental to this is the availability and employment of molecular markers, such as microsatellites and Single Nucleotide Polymorphisms (SNPs . Transcriptome sequences generated through sequencing-by-synthesis technology were utilized for the in vitro and in silico identification of 505 putative SNPs from a total of 316 selected contigs. A subset of 234 SNPs were further validated and characterized in wild and cultured abalone using two Illumina GoldenGate genotyping assays. Combined with VeraCode technology, this genotyping platform yielded a 65%−69% conversion rate (percentage polymorphic markers with a global genotyping success rate of 76%−85% and provided a viable means for validating SNP markers in a non-model species. The utility of 31 of the validated SNPs in population structure analysis was confirmed, while a large number of SNPs (174 were shown to be informative and are, thus, good candidates for linkage map construction. The non-synonymous SNPs (50 located in coding regions of genes that showed similarities with known proteins will also be useful for genetic applications, such as the marker-assisted selection of genes of relevance to abalone aquaculture.

  11. The effect of different polychlorinated biphenyls on two aquatic models, the green alga Pseudokirchneriella subcapitata and the haemocytes from the European abalone Haliotis tuberculata.

    Science.gov (United States)

    Halm-Lemeille, Marie-Pierre; Abbaszadeh Fard, Elham; Latire, Thomas; Ferard, Jean-François; Costil, Katherine; Lebel, Jean-Marc; Bureau, Ronan; Serpentini, Antoine

    2014-09-01

    The present study was conducted to determine the toxicity of different polychlorinated biphenyls (PCBs) on the green algae, Pseudokirchneriella subcapitata and the haemocytes from the European abalone, Haliotis tuberculata. Using the algal growth inhibition test, the green algae median Effective Concentration (EC50) values ranged from 0.34μM for PCB28 to more than 100μM for PCBs 101 and 153. Considering the MTT viability test, the abalone EC50 values ranged from 1.67μM for PCB153 to 89μM for PCB28. Our results in contrast to previous observation in vertebrates did not show significant differences between the dioxin like- and non dioxin like-PCBs toxicities regardless of the model used. However, our results demonstrated that the toxicities of PCBs were species dependent. For example, PCB28 was the most toxic compound for P. subcapitata whereas PCBs 1, 180 and 153 were less toxic for that species. On the contrary, PCB153 was reported as the most toxic for H. tuberculata haemocytes and PCB28 the least toxic. To investigate the mode of action of these compounds, we used an in silico method. Our results suggested that PCBs have a non-specific mode of action (e.g., narcosis) on green algae, and another mode of action, probably more specific than narcosis, was reported for PCBs on the abalone haemocytes. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Text of the agreement between the International Atomic Energy Agency, the United Nations Educational, Scientific and Cultural Organization and the Government of the Republic of Italy concerning the International Centre for Theoretical Physics at Trieste

    International Nuclear Information System (INIS)

    1996-02-01

    The text of the Agreement between the International Atomic Energy Agency, the United Nations Educational, Scientific and Cultural Organization and the Government of the Republic of Italy concerning the International Centre for Theoretical Physics at Trieste is reproduced in this document for the information of all Members. The Agreement was approved by the Agency's Board of Governors on 25 February 1993, by the UNESCO General Conference on 16 November 1993, and ratified by the Italian Parliament on 2 January 1995

  13. Text of the agreement between the International Atomic Energy Agency and the United Nations Educational, Scientific and Cultural Organization concerning the joint operation of the International Centre for Theoretical Physics at Trieste

    International Nuclear Information System (INIS)

    1996-02-01

    The text of the Agreement between the International Atomic Energy Agency and the United Nations Educational, Scientific and Cultural Organization concerning the Joint Operation of the International Centre for Theoretical Physics at Trieste is reproduced in this document for the information of all Members. The Agreement was approved by the Agency's Board of Governors on 25 February 1993 and by the UNESCO General Conference on 16 November 1993

  14. Effects of waterborne Cu and Cd on anti-oxidative response, lipid peroxidation and heavy metals accumulation in abalone Haliotis discus hannai ino

    Science.gov (United States)

    Lei, Yanju; Zhang, Wenbing; Xu, Wei; Zhang, Yanjiao; Zhou, Huihui; Mai, Kangsen

    2015-06-01

    The aim of this study was to compare the effects of waterborne copper (Cu) and cadmium (Cd) on survival, anti-oxidative response, lipid peroxidation and metal accumulation in abalone Haliotis discus hannai. Experimental animals (initial weight: 7.49 g ± 0.01 g) were exposed to graded concentrations of waterborne Cu (0.02, 0.04, 0.06, 0.08 mg L-1) or Cd (0.025, 0.05, 0.25, 0.5 mg L-1) for 28 days, respectively. Activities of the anti-oxidative enzymes (catalase, CAT; superoxide dismutase, SOD; glutathione peroxidases, GPx; glutathione S-transferase, GST), contents of the reduced glutathione (GSH) and malondiadehyde (MDA) in the hepatopancreas, and metal accumulation in hepatopancreas and muscles were analyzed after 0, 1, 3, 6, 10, 15, 21, 28 days of metal exposure, respectively. Results showed that 0.04 mg L-1, 0.06 mg L--1 and 0.08 mg L-1 Cu caused 100% death of abalone on the 21st, 10th and 6th day, respectively. However, no dead abalone was found during the 28-day waterborne Cd exposure at all experimental concentrations. Generally, activities of SOD and GST in hepatopancreas under all Cu concentrations followed a decrease trend as the exposure time prolonged. However, these activities were firstly increased and then decreased to the control level and increased again during Cd exposure. Activities of CAT in all Cu exposure treatments were higher than those in the control. These activities were firstly increased and then decreased to the control level and increased again during Cd exposure. Contents of MDA in hepatopancreas in all Cu treatments significantly increased first and then decreased to the control level. However, the MDA contents in hepatopancreas were not significantly changed during the 28-day Cd exposure. The metals accumulation in both hepatopancreas and muscles of abalone significantly increased with the increase of waterborne metals concentration and exposure time. These results indicated that H. discus hannai has a positive anti-oxidative defense

  15. Two duplicated chicken-type lysozyme genes in disc abalone Haliotis discus discus: molecular aspects in relevance to structure, genomic organization, mRNA expression and bacteriolytic function.

    Science.gov (United States)

    Umasuthan, Navaneethaiyer; Bathige, S D N K; Kasthuri, Saranya Revathy; Wan, Qiang; Whang, Ilson; Lee, Jehee

    2013-08-01

    Lysozymes are crucial antibacterial proteins that are associated with catalytic cleavage of peptidoglycan and subsequent bacteriolysis. The present study describes the identification of two lysozyme genes from disc abalone Haliotis discus discus and their characterization at sequence-, genomic-, transcriptional- and functional-levels. Two cDNAs and BAC clones bearing lysozyme genes were isolated from abalone transcriptome and BAC genomic libraries, respectively and sequences were determined. Corresponding deduced amino acid sequences harbored a chicken-type lysozyme (LysC) family profile and exhibited conserved characteristics of LysC family members including active residues (Glu and Asp) and GS(S/T)DYGIFQINS motif suggested that they are LysC counterparts in disc abalone and designated as abLysC1 and abLysC2. While abLysC1 represented the homolog recently reported in Ezo abalone [1], abLysC2 shared significant identity with LysC homologs. Unlike other vertebrate LysCs, coding sequence of abLysCs were distributed within five exons interrupted by four introns. Both abLysCs revealed a broader mRNA distribution with highest levels in mantle (abLysC1) and hepatopancreas (abLysC2) suggesting their likely main role in defense and digestion, respectively. Investigation of temporal transcriptional profiles post-LPS and -pathogen challenges revealed induced-responses of abLysCs in gills and hemocytes. The in vitro muramidase activity of purified recombinant (r) abLysCs proteins was evaluated, and findings indicated that they are active in acidic pH range (3.5-6.5) and over a broad temperature range (20-60 °C) and influenced by ionic strength. When the antibacterial spectra of (r)abLysCs were examined, they displayed differential activities against both Gram positive and Gram negative strains providing evidence for their involvement in bacteriolytic function in abalone physiology. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. From principles to action: Applying the National Research Council's principles for effective decision support to the Federal Emergency Management Agency's watch office

    Directory of Open Access Journals (Sweden)

    Alison M. Meadow

    2016-03-01

    Full Text Available The National Research Council (NRC proposed six principles for effective decision support in its 2009 report Informing Decisions in a Changing Climate. We structured a collaborative project between the Federal Emergency Management Agency Region R9 (FEMA R9, the Western Region Headquarters of the National Weather Service (WR-NWS, and the Climate Assessment of the Southwest (CLIMAS at the University of Arizona around the application of the NRC principles. The goal of the project was to provide FEMA R9's Watch Office with climate information scaled to their temporal and spatial interests to aid them in assessing the potential risk of flood disasters. We found that we needed specific strategies and activities in order to apply the principles effectively. By using a set of established collaborative research approaches we were better able to assess FEMA R9's information needs and WR-NWS's capacity to meet those needs. Despite our diligent planning of engagement strategies, we still encountered some barriers to transitioning our decision support tool from research to operations. This paper describes our methods for planning and executing a three-party collaborative effort to provide climate services, the decision support tool developed through this process, and the lessons we will take from this deliberate collaborative process to our future work and implications of the NRC principles for the broader field of climate services. Keywords: Climate services, Emergency management, Flood risk, Decision support

  17. Geological disposal of radioactive waste: national commitment, local and regional involvement - A Collective Statement of the OECD Nuclear Energy Agency Radioactive Waste Management Committee Adopted March 2012

    International Nuclear Information System (INIS)

    2012-01-01

    Disposal in engineered facilities built in stable, deep geological formations is the reference solution for permanently isolating long-lived radioactive waste from the human biosphere. This management method is designed to be intrinsically safe and final, meaning that it is not dependent on human presence or intervention in order to fulfil its safety goal. Selecting the site of a waste repository brings up a range of issues involving scientific knowledge, technical capacity, ethical values, territorial planning, community well-being and more. Bringing to fruition the multi-decade task of siting and developing a repository demands a strong national commitment and significant regional and local involvement. This collective statement by the Radioactive Waste Management Committee of the OECD Nuclear Energy Agency recognises the advances made towards greater transparency and dialogue among the diverse stakeholders concerned and identifies the fundamental elements needed to support national commitment and to foster territorial involvement. It concludes that technical and societal partners can develop shared confidence in the safety of geological repositories and jointly carry these projects forward [fr

  18. ANDRA - National Radioactive Waste Management Agency. Activity and sustainable development report 2010 - a year with Andra. Management report and financial statements 2010 - Managing today to prepare for tomorrow

    International Nuclear Information System (INIS)

    2011-01-01

    Created in 1979 within the CEA, the National Radioactive Waste Management Agency (ANDRA) was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied; - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories. This mission includes as well a public service mission in terms of i) collection of waste of the 'small-scale nuclear activities' producers or owners (including the so-called 'household' radioactive waste, i.e. waste owned by private individuals) and ii) clean-up and rehabilitation of orphan polluted sites; - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This mission includes as well an active policy of dialogue with stakeholders both at national and local level. This document is the activity and Sustainable Development Report, with the management and financial statements report, of the Andra for the year 2010

  19. Internet-facilitated commercial sexual exploitation of children: findings from a nationally representative sample of law enforcement agencies in the United States.

    Science.gov (United States)

    Mitchell, Kimberly J; Jones, Lisa M; Finkelhor, David; Wolak, Janis

    2011-03-01

    This article explores the variety of ways in which the Internet is used to facilitate the commercial sexual exploitation of children (CSEC) and provides national incidence estimates for the number of arrests involving such technology-facilitated crimes in 2006. The National Juvenile Online Victimization Study is a nationally representative longitudinal study of more than 2,500 local, county, state, and federal law enforcement agencies across the United States. The current article utilizes Wave 2 data, which surveyed arrests in 2006 for Internet-related sex crimes against minors. Detailed data were collected via telephone interviews with investigators about 1,051 individual arrest cases. Findings show that an estimated 569 arrests for Internet-facilitated commercial sexual exploitation of children (IF-CSEC) occurred in the United States in 2006. Offenders in IF-CSEC cases fell into two main categories: (1) those who used the Internet to purchase or sell access to identified children for sexual purposes including child pornography (CP) production (36% of cases), and (2) those who used the Internet to purchase or sell CP images they possessed but did not produce (64% of cases). Offenders attempting to profit from child sexual exploitation were more likely than those who were purchasing to have (a) prior arrests for sexual and nonsexual offenses, (b) a history of violence, (c) produced CP, (d) joined forces with other offenders, and (e) involved female offenders. Although the number of arrests for IF-CSEC crimes is relatively small, the victims of these crimes are a high-risk subgroup of youth, and the offenders who try to profit from these crimes are particularly concerning from a child welfare perspective.

  20. Genomic characterization and expression profiles upon bacterial infection of a novel cystatin B homologue from disk abalone (Haliotis discus discus).

    Science.gov (United States)

    Premachandra, H K A; Wan, Qiang; Elvitigala, Don Anushka Sandaruwan; De Zoysa, Mahanama; Choi, Cheol Young; Whang, Ilson; Lee, Jehee

    2012-12-01

    Cystatins are a large family of cysteine proteinase inhibitors which are involved in diverse biological and pathological processes. In the present study, we identified a gene related to cystatin superfamily, AbCyt B, from disk abalone Haliotis discus discus by expressed sequence tag (EST) analysis and BAC library screening. The complete cDNA sequence of AbCyt B is comprised of 1967 nucleotides with a 306 bp open reading frame (ORF) encoding for 101 amino acids. The amino acid sequence consists of a single cystatin-like domain, which has a cysteine proteinase inhibitor signature, a conserved Gly in N-terminal region, QVVAG motif and a variant of PW motif. No signal peptide, disulfide bonds or carbohydrate side chains were identified. Analysis of deduced amino acid sequence revealed that AbCyt B shares up to 44.7% identity and 65.7% similarity with the cystatin B genes from other organisms. The genomic sequence of AbCyt B is approximately 8.4 Kb, consisting of three exons and two introns. Phylogenetic tree analysis showed that AbCyt B was closely related to the cystatin B from pacific oyster (Crassostrea gigas) under the family 1.Functional analysis of recombinant AbCyt B protein exhibited inhibitory activity against the papain, with almost 84% inhibition at a concentration of 3.5 μmol/L. In tissue expression analysis, AbCyt B transcripts were expressed abundantly in the hemocyte, gill, mantle, and digestive tract, while weakly in muscle, testis, and hepatopancreas. After the immune challenge with Vibrio parahemolyticus, the AbCyt B showed significant (P<0.05) up-regulation of relative mRNA expression in gill and hemocytes at 24 and 6 h of post infection, respectively. These results collectively suggest that AbCyst B is a potent inhibitor of cysteine proteinases and is also potentially involved in immune responses against invading bacterial pathogens in abalone. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. Diplomatic agency

    DEFF Research Database (Denmark)

    Adler-Nissen, Rebecca

    2016-01-01

    diplomatic agency has been conceptualized in International Relations theory (English School, game theory, Foreign Policy Analysis, constructivism, practice theory, post-positivism) before presenting and exemplifying major and overlapping types of diplomatic agency, including communication, negotiation......, it discusses how diplomatic agency is linked to conceptions of diplomatic representation and legitimacy in its actual, functional and symbolic forms....

  2. Advertising Agencies

    DEFF Research Database (Denmark)

    Moeran, Brian

    2015-01-01

    Advertising agencies are the most significant organizations in the development of advertising and marketing worldwide. An advertising agency is an independent service company, composed of business, marketing and creative people, who develop, prepare, and place advertising in advertising media...... for their clients, the advertisers, who are in search of customers for their goods and services. Agencies thus mediate between three different but interlocking social groups: industry, media, and consumers. The history of advertising is largely the history of the advertising agencies that have served the needs....... This article is concerned with the origins, early developments, organization, compensation arrangements, and accounts of contemporary full-service advertising agencies....

  3. Comparative assessment of medicine procurement prices in the United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA).

    Science.gov (United States)

    Ewen, Margaret; Al Sakit, Maisa; Saadeh, Rawan; Laing, Richard; Vialle-Valentin, Catherine; Seita, Akihiro; Bunders, Joske

    2014-01-01

    The United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA), the main primary healthcare provider for 4.9 million Palestinian refugees, spent USD18.3 million on essential medicines dispensed free-of-charge through clinics in five areas of operation ('fields'): Gaza, Jordan, Lebanon, Syria, and the West Bank (2010). Faced with budget contraints and an increasing demand for medicines to treat chronic conditions, the objective of our study was to assess UNRWA's medicine procurement prices to see if savings could be possible. In July 2011, data was collected from UNRWA headquarters in Jordan. Price analyses focused on the top 80 medicines by value, accounting for 93% of pharmaceutical expenditure from the General Fund, with comparisons to international, regional and national references. Prices were also compared for the few medicines procured both through UNRWA's central tender (centrally) and by the fields directly (locally). Central procurement prices did not differ markedly from reference prices: median ratios of UNRWA prices to Management Sciences for Health's International Drug Price Indicator Guide, Jordan's Joint Procurement Department, Gulf Cooperation Council, and IDA Foundation bulk packs were 0.99, 1.00, 0.98 and 1.12 respectively. Applying the lowest comparator price to five comparatively higher priced medicines would yield savings of USD1.4 million. Local procurements were generally less cost-effective than central tender procurement, with notable differences across fields and medicines. Overall, UNRWA's procurement prices were competitive despite the relatively small quantities procured. Regular monitoring of procurement prices and quantities is needed in order to make informed decisions. Our evaluation also underscores the heavy burden of antidiabetic medicines and antimicrobials on UNRWA procurement expenditure.

  4. Argonne's performance assessment of major facility systems to support semiconductor manufacturing by the National Security Agency/R Group, Ft. Meade, Maryland

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, W.; Miller, G.M.

    1990-12-01

    The National Security Agency (NSA) was authorized in 1983 to construct a semiconductor and circuit-board manufacturing plant at its Ft. Meade, Maryland, facility. This facility was to become known as the Special Process Laboratories (SPL) building. Phase I construction was managed by the US Army Corps of Engineers, Baltimore District (USACE/BD) and commenced in January 1986. Phase I construction provided the basic building and support systems, such as the heating, ventilating, and air-conditioning system, the deionized-water and wastewater-treatment systems, and the high-purity-gas piping system. Phase II construction involved fitting the semiconductor manufacturing side of the building with manufacturing tools and enhancing various aspects of the Phase I construction. Phase II construction was managed by NSA and commenced in April 1989. Argonne National Laboratory (ANL) was contracted by USACE/BD midway through the Phase I construction period to provide quality-assured performance reviews of major facility systems in the SPL. Following completion of the Phase I construction, ANL continued its performance reviews under NSA sponsorship, focusing its attention on the enhancements to the various manufacturing support systems of interest. The purpose of this document is to provide a guide to the files that were generated by ANL during its term of technical assistance to USACE/BD and NSA and to explain the quality assurance program that was implemented when ANL conducted its performance reviews of the SPL building's systems. One set of the ANL project files is located at NSA, Ft. Meade, and two sets are at Argonne, Illinois. The ANL sets will be maintained until the year 2000, or for the 10-year estimated life of the project. 1 fig.

  5. Arrests for child pornography production: data at two time points from a national sample of U.S. law enforcement agencies.

    Science.gov (United States)

    Wolak, Janis; Finkelhor, David; Mitchell, Kimberly J; Jones, Lisa M

    2011-08-01

    This study collected information on arrests for child pornography (CP) production at two points (2000-2001 and 2006) from a national sample of more than 2,500 law enforcement agencies. In addition to providing descriptive data about an understudied crime, the authors examined whether trends in arrests suggested increasing CP production, shifts in victim populations, and challenges to law enforcement. Arrests for CP production more than doubled from an estimated 402 in 2000-2001 to an estimated 859 in 2006. Findings suggest the increase was related to increased law enforcement activity rather than to growth in the population of CP producers. Adolescent victims increased, but there was no increase in the proportion of arrest cases involving very young victims or violent images. Producers distributed images in 23% of arrest cases, a proportion that did not change over time. This suggests that much CP production may be primarily for private use. Proactive law enforcement operations increased, as did other features consistent with a robust law enforcement response.

  6. Implementing a national program to reduce catheter-associated urinary tract infection: a quality improvement collaboration of state hospital associations, academic medical centers, professional societies, and governmental agencies.

    Science.gov (United States)

    Fakih, Mohamad G; George, Christine; Edson, Barbara S; Goeschel, Christine A; Saint, Sanjay

    2013-10-01

    Catheter-associated urinary tract infection (CAUTI) represents a significant proportion of healthcare-associated infections (HAIs). The US Department of Health and Human Services issued a plan to reduce HAIs with a target 25% reduction of CAUTI by 2013. Michigan's successful collaborative to reduce unnecessary use of urinary catheters and CAUTI was based on a partnership between diverse hospitals, the state hospital association (SHA), and academic medical centers. Taking the lessons learned from Michigan, we are now spreading this work throughout the 50 states. This national spread leverages the expertise of different groups and organizations for the unified goal of reducing catheter-related harm. The key components of the project are (1) centralized coordination of the effort and dissemination of information to SHAs and hospitals, (2) data collection based on established definitions and approaches, (3) focused guidance on the technical practices that will prevent CAUTI, (4) emphasis on understanding the socioadaptive aspects (both the general, unit-wide issues and CAUTI-specific challenges), and (5) partnering with specialty organizations and governmental agencies who have expertise in the relevant subject area. The work may serve in the future as a model for other large improvement efforts to address other hospital-acquired conditions, such as venous thromboembolism and falls.

  7. Patient safety incidents associated with tracheostomies occurring in hospital wards: a review of reports to the UK National Patient Safety Agency.

    Science.gov (United States)

    McGrath, B A; Thomas, A N

    2010-09-01

    Tracheostomies are increasingly common in hospital wards due to the rising use of percutaneous and surgical tracheostomies in critical care and bed pressures in these units. Hospital wards may lack appropriate infrastructure to care for this vulnerable group and significant patient harm may result. To identify and analyse tracheostomy related incident reports from hospital wards between 1 October 2005 and 30 September 2007, and to make recommendations to improve patient safety based on the recurrent themes identified. The study was performed between August 2008 and August 2009. 968 tracheostomy related critical incidents reported to the National Patient Safety Agency over the 2 year period, identified by key letter searches, were analysed. Incidents were categorised to identify common themes, and root cause analysis attempted where possible. In the 453 incidents where patients were directly affected, 338 (75%) were associated with some identifiable patient harm, of which 83 (18%) were associated with more than temporary harm. In 29 incidents (6%) some intervention was required to maintain life, and in 15 cases the incident may have contributed to the patient's death. Equipment was involved in 176 incidents and 276 incidents involved tracheostomies becoming blocked or displaced. By identifying and analysing themes in incident reports associated with tracheostomies, recommendations can be made to improve safety for this group of patients. These recommendations include improvements in infrastructure, competency and training, equipment provision, and in communication.

  8. Statement to the 35th session of the General Conference of the International Atomic Energy Agency 16 September 1991; Statement to the 46th session of the United Nations General Assembly 21 October 1991

    International Nuclear Information System (INIS)

    Blix, H.

    1991-01-01

    The document contains the following two statements of Hans Blix, Director General of the IAEA: Statement to the 35th session of the General Conference of the International Atomic Energy Agency, 16 September 1991; Statement to the 46th session of the United Nations General Assembly, 21 October 1991. A separate abstract was prepared for each of these statements

  9. Statement to the 41st session of the General Conference of the International Atomic Energy Agency 29 September 1997; Statement to the 52nd session of the United Nations General Assembly 12 November 1997

    International Nuclear Information System (INIS)

    Blix, H.

    1997-12-01

    The document presents Statement to the 41st Session of the General Conference of the International Atomic Energy Agency and Statement to the 52nd Session of the United Nations General Assembly made at the 40th anniversary of the IAEA

  10. Statement to the 34th session of the general conference of the International Atomic Energy Agency, 17 September 1990. Statement to the 45th session of the United Nations general assembly, 23 October 1990

    International Nuclear Information System (INIS)

    Blix, H.

    1991-01-01

    The document contains the following two statements of Hans Blix, Director General of the IAEA: Statement to the 34th Session of the General Conference of the International Atomic Energy Agency, 17 September 1990; Statement to the 45th Session of the United Nations General Assembly, 23 October 1990. A separate abstract was prepared for each of these statements

  11. The Agency's Agreement with the United Nations Educational, Scientific and Cultural Organization concerning the Joint Operation of the International Centre for Theoretical Physics at Trieste. Extension of the Agreement

    International Nuclear Information System (INIS)

    1983-02-01

    By an exchange of letters between the Directors General of the United Nations Educational, Scientific and Cultural Organization (UNESCO) and the Agency, the duration of the agreement between the two organizations concerning the joint operation of the International Centre for Theoretical Physics at Trieste has been extended until 31 December 1986.

  12. Statement to the 40th session of the General Conference of the International Atomic Energy Agency 16 September 1996; Statement to the 51st session of the United Nations General Assembly 28 October 1996

    International Nuclear Information System (INIS)

    Blix, H.

    1996-11-01

    In the Statement to the 40th Session of the General Conference of the International Atomic Energy Agency main directions of the IAEA activities and plans for the future are outlined. In the Statement to the 51th Session of the United Nations General Assembly main achievements and challenge facing the international community in the field of IAEA competence are discussed

  13. Marine environmental impact assessment of abalone, Haliotis discus hannai, cage farm in Wan-do, Republic of Korea

    Science.gov (United States)

    Oh, Hyun-Taik; Jung, Rae-Hong; Cho, Yoon-Sik; Hwang, Dong-Woon; Yi, Yong-Min

    2015-12-01

    To assess the marine environmental impacts of abalone, Haliotis discus hannai, cage farms in Wan-do, we monitored the benthic environment on top of the sediment underneath cage farm stations and reference stations. We applied two methods for this assessment. One was the A- and B-investigation of the MOM system (Modeling-On fish farm-Monitoring) developed in Norway. The other was a general environmental monitoring method which is widely used. In this study, we found benthic animals in all samples that belonged to condition 1 which were based on group 1(presence of macrofauna) of the B-investigation method. The values of redox potential (group 2-pH, redox potential) in all samples were above +65 mV belonging to condition 1. Based on sensory results (group 3-gas, color, odor, thickness of deposits), five out of seven experiment samples showed condition 1 while stations 2 and 7 showed condition 2, which have been cultured for 10 years in semi-closed waters. As group 2 takes precedence over group 3, the level of the conditions for B-investigation results consequently showed condition 1 in all stations. We found that pollutants and trace metals in the sediment underneath cage farms were lower than the pollution standard. This led us to conclude that the environmental impacts of the cage farms in this study were not significant.

  14. iTRAQ-Based Identification of Proteins Related to Muscle Growth in the Pacific Abalone, Haliotis discus hannai

    Directory of Open Access Journals (Sweden)

    Jianfang Huang

    2017-10-01

    Full Text Available The abalone Haliotis discus hannai is an important aquaculture species that is grown for human consumption. However, little is known of the genetic mechanisms governing muscle growth in this species, particularly with respect to proteomics. The isobaric tag for relative and absolute quantitation (iTRAQ method allows for sensitive and accurate protein quantification. Our study was the first to use iTRAQ-based quantitative proteomics to investigate muscle growth regulation in H. discus hannai. Among the 1904 proteins identified from six samples, 125 proteins were differentially expressed in large specimens of H. discus hannai as compared to small specimens. In the large specimens, 47 proteins were upregulated and 78 were downregulated. Many of the significant Kyoto Encyclopedia of Genes and Genomes (KEGG pathways, including these differentially expressed proteins, were closely related to muscle growth, including apoptosis, thyroid hormone signaling, regulation of the actin cytoskeleton, and viral myocarditis (p < 0.05. Our quantitative real-time polymerase chain reaction (qRT-PCR analyses suggested that the alterations in expression levels observed in the differentially expressed proteins were consistent with the alterations observed in the encoding mRNAs, indicating the repeatability of our proteomic approach. Our findings contribute to the knowledge of the molecular mechanisms of muscle growth in H. discus hannai.

  15. Effects of abalone (Haliotis discus hannai Ino) gonad polysaccharides on cholecystokinin release in STC-1 cells and its signaling mechanism.

    Science.gov (United States)

    Zhao, Jun; Zhou, Da-Yong; Yang, Jing-Feng; Song, Shuang; Zhang, Ting; Zhu, Ce; Song, Yan-Qing; Yu, Chen-Xu; Zhu, Bei-Wei

    2016-10-20

    Abalone gonad polysaccharide (AGP) -31, -32 and -33 prepared in this study had the molecular weight (MW) of 37.8, 32.2 and 27.5kDa, respectively. They all contained mannose, rhamnose, glucuronic acid, glucose, galactose, xylose, arabinose, and fucose, with very similar monosaccharide profile. All the three polysaccharides could significantly increase the secretion of cholecystokinin (CCK) in STC-1 cells. Among them, AGP-32 showed the strongest effect. However, the low-MW fragments of AGP-32 showed significantly lower activity than AGP-32 itself. It was also found that the inhibitors on calcium-sensing receptor (CaSR), protein kinase A (PKA), Ca(2+)⁄calmodulin-dependent protein kinase (CaMK) II, p38- mitogen-activated protein kinases (MAPK), and an intracellular calcium chelator all inhibited AGP-induced CCK secretion. To conclude, Ca(2+)/calmodulin (CaM)/CaMK, cyclic adenosine monophosphate (cAMP)/PKA and MAPK pathways are all involved in AGP-induced CCK secretion. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Proteomic analysis of muscle between hybrid abalone and parental lines Haliotis gigantea Reeve and Haliotis discus hannai Ino.

    Science.gov (United States)

    Di, G; Luo, X; You, W; Zhao, J; Kong, X; Ke, C

    2015-06-01

    To understand the potential molecular mechanism of heterosis, protein expression patterns were compared from hybrids of Haliotis gigantea (G) and Haliotis discus hannai (D) using two-dimensional gel electrophoresis (2-DE) and matrix-assisted laser desorption/ionization time-of-flight/time-of-flight analyses. Expression differences were observed in muscle samples from the four groups with 673±21.0 stained spots for H. discus hannai ♀ × H. discus hannai ♂ (DD), 692±25.6 for H. gigantea ♀ × H. gigantea ♂ (GG), 679±16.2 for H. discus hannai ♀ × H. gigantea ♂ (DG) (F1 hybrid) and 700±19 for H. gigantea ♀ × H. discus hannai ♂ (GD) (F1 hybrid). Different 2-DE image muscle protein spots had a mirrored relationship between purebreds and the F1 hybrid, suggesting that all stained spots in F1 hybrid muscle were on 2-DEs from parents. DD and DG clustered together first, and then clustered with GD, whereas the distance of DD and GG was maximal according to hierarchical cluster analysis. We identified 136 differentially expressed protein spots involved in major biological processes, including energy metabolism and stress response. Most energy metabolism proteins were additive, and stress-induced proteins displayed additivity or over-dominance. In these 136 identified protein spots, hybrid offspring with additivity or over-dominance accounted for 68.38%. Data show that a proteomic approach can provide functional prediction of abalone interspecific hybridization.

  17. Molecular identification and functional analysis of two variants of myeloid differentiation factor 88 (MyD88) from disk abalone (Haliotis discus discus).

    Science.gov (United States)

    Priyathilaka, Thanthrige Thiunuwan; Bathige, S D N K; Lee, Seongdo; Lee, Jehee

    2018-02-01

    Myeloid differentiation factor 88 (MyD88) is a crucial adaptor protein of the Toll-like receptor (TLR)- and interleukin 1 receptor-mediated signaling pathways and is involved in a diverse array of inflammatory responses via NF-κB activation. In the present study, two MyD88 variants were identified from disk abalone (Haliotis discus discus) and designated AbMyD88-2 and AbMyD88-X. The deduced AbMyD88-2 and AbMyD88-X comprised 433 and 354 amino acids with predicted molecular masses of 48.85 kDa and 40.17 kDa, respectively. AbMyD88-2 and AbMyD88-X possessed typical MyD88 domain structural features including an N-terminal death domain (DD) and C-terminal toll interleukin 1 receptor (TIR) domain similar to those in mammals. Expression analysis of AbMyD88-2 and AbMyD88-X mRNA at different early embryonic developmental stages of abalone by qPCR revealed that their constitutive expression at all developmental stages analyzed with the considerably higher values at the 16-cell (AbMyD88-2) and morula stages (AbMyD88-X). In unchallenged disk abalones, AbMyD88-2 was highly expressed in muscles, while AbMyD88-X mRNA was predominantly transcribed in hemocytes. Moreover, AbMyD88-2 and AbMyD88-X mRNA were differentially modulated in abalone hemocytes after a challenge with live bacteria (Vibrio parahaemolyticus, Listeria monocytogenes), virus (viral hemorrhagic septicemia virus), and pathogen-associated molecular patterns (lipopolysaccharides and Poly I:C). Overexpression of AbMyD88-2 and AbMyD88-X in HEK293T cells induced the activation of the NF-κB promoter. AbMyD88-2 and AbMyD88-X involvement in inflammatory responses was characterized by their overexpression in RAW264.7 murine macrophage cells. These results revealed comparatively higher NO (Nitric oxide) production, induction of inflammatory mediator genes (iNOS and COX2), and proinflammatory genes (IL1β, IL6 and TNFα) expression in abalone MyD88s-overexpressing cells than in mock control in the presence or absence of LPS

  18. Mitogen-activated protein kinase 1 from disk abalone (Haliotis discus discus): Roles in early development and immunity-related transcriptional responses.

    Science.gov (United States)

    Perera, N C N; Godahewa, G I; Lee, Jehee

    2016-12-01

    Mitogen-activated protein kinase (MAPK) is involved in the regulation of cellular events by mediating signal transduction pathways. MAPK1 is a member of the extracellular-signal regulated kinases (ERKs), playing roles in cell proliferation, differentiation, and development. This is mainly in response to growth factors, mitogens, and many environmental stresses. In the current study, we have characterized the structural features of a homolog of MAPK1 from disk abalone (AbMAPK1). Further, we have unraveled its expressional kinetics against different experimental pathogenic infections or related chemical stimulants. AbMAPK1 harbors a 5' untranslated region (UTR) of 23 bps, a coding sequence of 1104 bps, and a 3' UTR of 448 bp. The putative peptide comprises a predicted molecular mass of 42.2 kDa, with a theoretical pI of 6.28. Based on the in silico analysis, AbMAPK1 possesses two N-glycosylation sites, one S_TK catalytic domain, and a conserved His-Arg-Asp domain (HRD). In addition, a conservative glycine rich ATP-phosphate-binding loop and a threonine-x-tyrosine motif (TEY) important for the autophosphorylation were also identified in the protein. Homology assessment of AbMAPK1 showed several conserved regions, and ark clam (Aplysia californica) showed the highest sequence identity (87.9%). The phylogenetic analysis supported close evolutionary kinship with molluscan orthologs. Constitutive expression of AbMAPK1 was observed in six different tissues of disk abalone, with the highest expression in the digestive tract, followed by the gills and hemocytes. Highest AbMAPK1 mRNA expression level was detected at the trochophore developmental stage, suggesting its role in abalone cell differentiation and proliferation. Significant modulation of AbMAPK1 expression under pathogenic stress suggested its putative involvement in the immune defense mechanism. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Molluscan death effector domain (DED)-containing caspase-8 gene from disk abalone (Haliotis discus discus): molecular characterization and expression analysis.

    Science.gov (United States)

    Lee, Youngdeuk; De Zoysa, Mahanama; Whang, Ilson; Lee, Sukkyoung; Kim, Yucheol; Oh, Chulhong; Choi, Cheol Young; Yeo, Sang-Yeob; Lee, Jehee

    2011-02-01

    The caspase family represents aspartate-specific cysteine proteases that play key roles in apoptosis and immune signaling. In this study, we cloned the first death effector domain (DED)-containing molluscan caspase-8 gene from disk abalone (Haliotis discus discus), which is named as hdCaspase-8. The full-length hdCaspase was 2855 bp, with a 1908 bp open reading frame encoding 636 amino acids. The hdCaspase-8 had 72 kDa predicted molecular mass with an estimated isoelectric point (PI) of 6.0. The hdCaspase-8 amino acid sequence contained the characteristic feature of an N-terminal two DED, a C-terminal catalytic domain and the caspase family cysteine active site ⁵¹³KPKLFFLQACQG⁵²⁴. Phylogenetic analysis results showed that hdCaspase-8 is more similar to the invertebrate Tubifex tubifex (sludge worm) caspase-8. Real-time RT-PCR results showed that hdCaspase-8 constitutively and ubiquitously expressed in all tested tissue of unchallenged disk abalone. The basal expression level of hdCaspase-8 in gill tissue was higher than all other tested tissues. The hdCaspase-8 mRNA expression in gill and hemocytes was significantly up-regulated by exposure to bacteria (Vibrio alginolyticus, Vibrio parahemolyticus and Listeria monocytogenes) and VHSV (viral hemorrhagic septicemia virus), as compared to control animals. These results suggest that hdCaspase-8 may be involved in immune response reactions in disk abalone. Copyright © 2010 Elsevier Ltd. All rights reserved.

  20. Molecular identification and functional delineation of a glutathione reductase homolog from disk abalone (Haliotis discus discus): Insights as a potent player in host antioxidant defense.

    Science.gov (United States)

    Herath, H M L P B; Wickramasinghe, P D S U; Bathige, S D N K; Jayasooriya, R G P T; Kim, Gi-Young; Park, Myoung Ae; Kim, Chul; Lee, Jehee

    2017-01-01

    Glutathione reductase (GSR) is an enzyme that catalyzes the biochemical conversion of oxidized glutathione (GSSG) into the reduced form (GSH). Since the ratio between the two forms of glutathione (GSH/GSSG) is important for the optimal function of GSH to act as an antioxidant against H 2 O 2 , the contribution of GSR as an enzymatic regulatory agent to maintain the proper ratio is essential. Abalones are marine mollusks that frequently encounter environmental factors that can trigger the overproduction of reactive oxygen species (ROS) such as H 2 O 2 . Therefore, we conducted the current study to reveal the molecular and functional properties of a GSR homolog in the disk abalone, Haliotis discus discus. The identified cDNA sequence (2325 bp) has a 1356 bp long open reading frame (ORF), coding for a 909 bp long amino acid sequence, which harbors a pyridine nucleotide-disulfide oxidoreductase domain (171-246 aa), a pyridine nucleotide-disulfide oxidoreductase dimerization domain, and a NAD(P)(+)-binding Rossmann fold superfamily signature domain. Four functional residues: the FAD binding site, glutathione binding site, NADPH binding motif, and assembly domain were identified to be conserved among the other species. The recombinant abalone GSR (rAbGSR) exhibited detectable activity in a standard glutathione reductase activity assay. The optimum pH and optimal temperature for the reaction were found to be 7.0 and 50 °C, respectively, while the ionic strength of the medium had no effect. The enzymatic reaction was vastly inhibited by Cu +2 and Cd +2 ions. A considerable effect of cellular protection was detected with a disk diffusion assay conducted with rAbGSR. Moreover, an MTT assay and flow cytometry confirmed the significance of the protective role of rAbGSR in cell function. Furthermore, AbGSR was found to be ubiquitously distributed in different types of abalone tissues. AbGSR mRNA expression was significantly upregulated in response to three immune challenges

  1. Molecular characterization of kappa class glutathione S-transferase from the disk abalone (Haliotis discus discus) and changes in expression following immune and stress challenges.

    Science.gov (United States)

    Sandamalika, W M Gayashani; Priyathilaka, Thanthrige Thiunuwan; Liyanage, D S; Lee, Sukkyoung; Lim, Han-Kyu; Lee, Jehee

    2018-04-02

    Glutathione S-transferase (GST; EC 2.5.1.18) isoenzymes represent a complex group of proteins that are involved in phase II detoxification in several organisms. In this study, GST kappa (GSTκ) from the disk abalone (Haliotis discus discus; AbGSTκ) was characterized at both the transcriptional and functional levels to determine its potential capacity to perform as a detoxification agent under conditions of different stress. The predicted AbGSTκ protein consists of 227 amino acids, with a predicted molecular weight of 25.6 kDa and a theoretical isoelectric point (pI) of 7.78. In silico analysis reveals that AbGSTκ is a disulfide bond formation protein A (DsbA), consisting of a thioredoxin domain, GSH binding sites (G-sites), and a catalytic residue. In contrast, no hydrophobic ligand binding site (H-site), or signal peptides, were detected. AbGSTκ showed the highest sequence identity with the orthologue from pufferfish (Takifugu obscurus) (60.0%). In a phylogenetic tree, AbGSTκ clustered closely together with other fish GSTκs, and was evolutionarily distanced from other cytosolic GSTs. The predicted three-dimensional structure clearly demonstrates that the dimer adopts a butterfly-like shape. A tissue distribution analysis revealed that GSTκ was highly expressed in the digestive tract, suggesting it has detoxification ability. Depending on the tissue and time, AbGSTκ showed different expression patterns, and levels of expression, following challenge of the abalone with immune stimulants. Enzyme kinetics of the purified recombinant proteins demonstrated its conjugating ability using 1-Chloro-2,4-dinitrobenzene (CDNB) and glutathione (GSH) as substrates, and suggested it has a low affinity for both substrates. The optimum temperature and pH for the rAbGSTκ GSH: CDNB conjugating activity were found to be 35 °C and pH 8, respectively indicating that the abalone is well adapted to a wide range of environmental conditions. Cibacron blue (100 μM) was

  2. Patient safety incidents associated with obesity: a review of reports to the National Patient Safety Agency and recommendations for hospital practice.

    Science.gov (United States)

    Booth, C M A; Moore, C E; Eddleston, J; Sharman, M; Atkinson, D; Moore, J A

    2011-10-01

    The incidence and prevalence of obesity are increasing world wide. In the UK, obesity governmental strategy has primarily focused on prevention measures, with less focus on the demands of treating obese patients in hospital. Increasing service demand by obese patients coupled with a lack of adequate provision for care of these patients may lead to an increase in patient safety incidents. By classifying patient safety incidents associated with obesity reported to the National Patient Safety Agency, this report aims to identify areas for improvement in the quality and safety of care of the obese patient. A search of the National Reporting and Learning System database was conducted for all incidents caused by or relating to obesity for the period 1 January 2005 to 31 August 2008. The keywords 'obesity', 'overweight', 'BMI' (body mass index), and 'bariatric' were used. The relevant free text fields of the resulting set of incidents were then searched for the terms designed to isolate incidents occurring in anaesthesia, critical care, and surgery. Reported incidents were analysed and subsequently categorised to identify incident themes. Levels of harm were also established. 555 patient safety incidents were identified; 388 met inclusion criteria for analysis. 148 incidents were related to assessment, diagnosis or treatment, 213 related to infrastructure and 27 related to staffing. The majority of incidents were classified as no or low harm. Three deaths were reported, all within the domain of anaesthesia. This report identifies that the majority of safety incidents associated with obesity were related to infrastructure, suggesting that there is inadequate provision in place for the care of obese patients. While levels of harm were mostly low, the occurrence of incidents resulting in severe harm or death highlights the specific dangers associated with the care of the obese patient. A global approach to improving the safety of care delivery for obese patients is

  3. Agency Theory

    DEFF Research Database (Denmark)

    Linder, Stefan; Foss, Nicolai Juul

    2015-01-01

    Agency theory studies the problems and solutions linked to delegation of tasks from principals to agents in the context of conflicting interests between the parties. Beginning from clear assumptions about rationality, contracting, and informational conditions, the theory addresses problems of ex...... agency theory to enjoy considerable scientific impact on social science; however, it has also attracted considerable criticism....

  4. Diplomatic agency

    DEFF Research Database (Denmark)

    Adler-Nissen, Rebecca

    2016-01-01

    diplomatic agency has been conceptualized in International Relations theory (English School, game theory, Foreign Policy Analysis, constructivism, practice theory, post-positivism) before presenting and exemplifying major and overlapping types of diplomatic agency, including communication, negotiation......Diplomatic agency is intriguing. On the one hand, diplomats are crucial to the management of day-to-day international relations and the negotiation of war and peace. On the other hand, most diplomatic action is highly constrained or invisible. This chapter provides an overview of the ways in which...... and advocacy. It analyzes how professionalization, legalization, personalization and popularization of diplomacy have shaped diplomatic agency including how international law, bureaucracy, public diplomacy and new information technologies have impacted the scope and content of diplomatic agency. Finally...

  5. Anti-allergic effects of a nonameric peptide isolated from the intestine gastrointestinal digests of abalone (Haliotis discus hannai) in activated HMC-1 human mast cells.

    Science.gov (United States)

    Ko, Seok-Chun; Lee, Dae-Sung; Park, Won Sun; Yoo, Jong Su; Yim, Mi-Jin; Qian, Zhong-Ji; Lee, Chang-Min; Oh, Junghwan; Jung, Won-Kyo; Choi, Il-Whan

    2016-01-01

    The aim of the present study was to examine whether the intestine gastrointestinal (GI) digests of abalone [Haliotis discus hannai (H. discus hannai)] modulate inflammatory responses and to elucidate the mechanisms involved. The GI digests of the abalone intestines were fractionated into fractions I (>10 kDa), II (5-10 kDa) and Ⅲ (<5 kDa). Of the abalone intestine GI digests (AIGIDs), fraction Ⅲ inhibited the passive cutaneous anaphylaxis (PCA) reaction in mice. Subsequently, a bioactive peptide [abalone intestine GI digest peptide (AIGIDP)] isolated from fraction Ⅲ was determined to be 1175.2 Da, and the amino acid sequence was found to be PFNQGTFAS. We noted that the purified nonameric peptide (AIGIDP) attenuated the phorbol‑12‑myristate 13-acetate plus calcium ionophore A23187 (PMACI)-induced histamine release and the production of pro-inflammatory cytokines, such as tumor necrosis factor-α (TNF-α), interleukin (IL)-1β and IL-6 in human mast cells (HMC-1 cells). In addition, we also noted that AIGIDP inhibited the PMACI‑induced activation of nuclear factor‑κB (NF-κB) by suppressing IκBα phosphorylation and that it suppressed the production of cytokines by decreasing the phosphorylation of JNK. The findings of our study indicate that AIGIDP exerts a modulatory, anti-allergic effect on mast cell-mediated inflammatory diseases.

  6. First characterisation of the populations and immune-related activities of hemocytes from two edible gastropod species, the disk abalone, Haliotis discus discus and the spiny top shell, Turbo cornutus.

    Science.gov (United States)

    Donaghy, Ludovic; Hong, Hyun-Ki; Lambert, Christophe; Park, Heung-Sik; Shim, Won Joon; Choi, Kwang-Sik

    2010-01-01

    The disk abalone Haliotis discus discus and the spiny top shell Turbo cornutus are edible gastropod species of high economic value, mainly in Asia. Mortality outbreaks and variations in worldwide stock abundance have been reported and suggested to be associated, at least in part, with pathogenic infections. Ecology, biology and immunology of both species are currently not well documented. The characterisation of the immune systems of these species is necessary to further assess the responses of H. discus discus and T. cornutus to environmental, chemical and disease stresses. In the present study, we investigated the morphology and immune-related activities of hemocytes in both species using light microscopy and flow cytometry. Two types of hemocytes were identified in the disk abalone hemolymph, blast-like cells and hyalinocytes; whereas four main hemocyte types were distinguished in the spiny top shell, blast-like cells, type I and II hyalinocytes, and granulocytes. Flow cytometric analysis also revealed differences between cell types in immune-related activities. Three subsets of hemocytes, defined by differing lysosomal characteristics, were observed in the hemolymph of the spiny top shell, and only one in the disk abalone. Phagocytic activity was higher in H. discus discus hemocytes than in T. cornutus hemocytes, and the kinetics of PMA-stimulated oxidative activity was different between hemocytes of the disk abalone and the spiny top shell. Finally our results suggest for the first time a predominant mitochondrial origin of oxidative activity in gastropod hemocytes. Copyright 2009 Elsevier Ltd. All rights reserved.

  7. Agency Theory

    DEFF Research Database (Denmark)

    Linder, Stefan; Foss, Nicolai Juul

    Agency theory studies the problems and solutions linked to delegation of tasks from principals to agents in the context of conflicting interests between the parties. Beginning from clear assumptions about rationality, contracting and informational conditions, the theory addresses problems of ex a...... agency theory to enjoy considerable scientific impact on social science; however, it has also attracted considerable criticism.......Agency theory studies the problems and solutions linked to delegation of tasks from principals to agents in the context of conflicting interests between the parties. Beginning from clear assumptions about rationality, contracting and informational conditions, the theory addresses problems of ex...

  8. Molecular characterization of collagen IV evidences early transcription expression related to the immune response against bacterial infection in the red abalone (Haliotis rufescens).

    Science.gov (United States)

    Chovar-Vera, Ornella; Valenzuela-Muñoz, Valentina; Gallardo-Escárate, Cristian

    2015-02-01

    Collagen IV has been described as a structural protein of the basement membrane, which as a whole forms a specialized extracellular matrix. Recent studies have indicated a possible relationship between collagen IV and the innate immune response of invertebrate organisms. The present study characterized the alpha-1 chain of collagen IV in the red abalone Haliotis rufescens (Hr-ColIV) and evaluated its association with the innate immune response against Vibrio anguillarum. To further evidence the immune response, the matrix metalloproteinase-1 (Hr-MMP-1) and C-type lectin (Hr-CLEC) genes were also assessed. The complete sequence of Hr-ColIV was composed of 6658 bp, with a 5'UTR of 154 bp, a 3'UTR of 1177 bp, and an ORF of 5327 bp that coded for 1776 amino acids. The innate immune response generated against V. anguillarum resulted in a significant increase in the transcript levels of Hr-ColIV between 3 and 6 hpi, whereas Hr-MMP-1 and Hr-CLEC had the highest transcript activity 6 and 12 hpi, respectively. The results obtained in this study propose a putative biological function for collagen IV involved in the early innate immune response of the red abalone H. rufescens. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. HdhCTL1 is a novel C-type lectin of abalone Haliotis discus hannai that agglutinates Gram-negative bacterial pathogens.

    Science.gov (United States)

    Zhang, Jian; Qiu, Reng; Hu, Yong-hua

    2014-12-01

    C-type lectins (CTLs) are Ca(2+)-dependent carbohydrate recognition proteins, which play important roles in the innate immunity of both vertebrates and invertebrates. In this study, we identified and characterized a C-type lectin (named HdhCTL1) from Pacific abalone, Haliotis discus hannai. HdhCTL1 is composed of 176 amino acid residues and shares low (23.9%) identity with the known CTL of abalone. HdhCTL1 possesses a putative signal peptide and a carbohydrate-recognition domain (CRD) typical of CTLs. The CRD of HdhCTL1 contains four disulfide bond-forming cysteine residues that are highly conserved in CTLs. HdhCTL1 mRNA was detected in a wide range of tissues and expressed abundantly in the digestive gland. Experimental infection with the bacterial pathogen Vibrio anguillarum significantly upregulated HdhCTL1 expression in a time-dependent manner. Recombinant HdhCTL1 (rHdhCTL1) purified from Escherichia coli was able to agglutinate Gram-negative bacterial pathogens. The agglutinating ability of rHdhCTL1 was abolished in the presence of mannose. These results suggest that HdhCTL1 is a novel CTL which is likely to be involved in host defense against bacterial infection. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Molecular characterization and mRNA expression during metal exposure and thermal stress of copper/zinc- and manganese-superoxide dismutases in disk abalone, Haliotis discus discus.

    Science.gov (United States)

    Kim, Keun-Yong; Lee, Sang Yoon; Cho, Young Sun; Bang, In Chul; Kim, Ki Hong; Kim, Dong Soo; Nam, Yoon Kwon

    2007-11-01

    Complementary DNAs encoding copper/zinc superoxide dismutase (Cu/Zn-SOD; SOD1) and manganese superoxide dismutase (Mn-SOD; SOD2) were isolated from disk abalone, Haliotis discus discus. The open reading frame sequences of Cu/Zn- and Mn-SODs encoded 154 and 226 amino acids, respectively. Multiple sequence alignments using the deduced amino acid sequences revealed that both abalone SODs showed considerable sequence similarities with their orthologues from diverse aerobic organisms, in which the amino acid residues forming metal ligands were highly conserved. All phylogenetic trees for both SOD genes inferred from maximum likelihood and Bayesian inference analyses presented the monophyletic status of Teleostei and Aves/Tetrapoda clades, and recovered relatively close genetic affiliation of H. discus discus with some molluscan species. Expression of both SODs at mRNA levels were highly modulated in various tissues (gill, muscle and hepatopancreas from juveniles, and haemocytes from adults) by experimental exposures to heavy metals (copper, zinc and cadmium) and also by thermal treatments (elevation of temperature). The mRNA levels of both SODs were increased in general during the metal or thermal treatments; however, the transcriptional responses of SOD genes were quite variable depending upon isoforms and tissues based on semi-quantitative and/or real-time RT-PCR assays.

  11. Ultrastructural description of new Rickettsia-like organisms in the commercial abalone Haliotis tuberculata (Gastropoda: Haliotidae) from the NW of Spain.

    Science.gov (United States)

    Azevedo, Carlos; Conchas, Ramón F; Tajdari, Jessica; Montes, Jaime

    2006-08-30

    Rickettsia-like organisms (RLOs) were found in the commercially farmed abalone Haliotis tuberculata in the northwestern region of the Atlantic Coast of Spain and are described from light and transmission electron microscopy observations. The RLOs measured approximately 1.6 x 0.9 microm and were found in intracytoplasmic, spherical to ellipsoidal vacuoles (up to 8 microm) in the epithelial cells of the digestive diverticulae. The morphological ultrastructure of these organisms was typically prokaryotic, including a plasmalemma and a thin Gram-negative type cell wall. Several ultrastructural changes were observed in the epithelial cells of the host containing the RLOs. The nuclei became pycnotic and several basophilic dense inclusions appeared in the cytoplasm. In addition, the host cell appeared lysed and was ruptured in advanced stages of infection. It was impossible to ascertain whether the RLOs are responsible for this disease, as a haplosporidian infection was also present. We can only conclude that the presence of RLOs simultaneously with a haplosporidian parasite may contribute to the mortality of the abalone host.

  12. National and international agencies demands and the implementation of an integrated management system: advantages of certification; As demandas dos orgaos nacionais e internacionais e a implementacao do Sistema de Gestao Integrado - SGI: vantagens da certificacao

    Energy Technology Data Exchange (ETDEWEB)

    Pessoa, Maria Eduarda C. [Queiroz Galvao Perfuracoes S.A., Rio de Janeiro, RJ (Brazil). Coordenacao de Meio Ambiente

    2004-07-01

    During the 80's, companies started to be concerned with more than their production processes. Due to the demands for products and services quality, in 1987, ISO 9000 (International Standards Organization) was established. Ten years later, ISO 14000 was established, regarding environmental management system, and in the same period BS 8800 (British Standards) and OHSAS 18001 (Occupational Health and Safety Assessment Series) were also published, regarding occupational health and safety in the working environment. With the increasing demands for companies that participate with the country's economical and social development, SA 8000 was elaborated. In the present days, companies that do not incorporate these factors (quality, environment, occupational health, safety, and social responsibility), has its markets diminished. For several countries, especially European countries, environmental and social aspects are essential for companies and products to gain entry into their markets. The implementation of such systems therefore aids companies to manage their aspects, leading to continuous process improval and the opening of new markets. A company's success depends more of the demands of national and international agencies (financing or licensing agencies, for example). Financing agencies have to assure themselves that they are investing in environmentally and socially friendly projects. Licensing agencies require that specific projects take place with the smallest possible environmental impact. The existence of a management system in the company that incorporates environmental management facilitates the licensing process, as well as financing by multilateral national and international agencies. Certification therefore acts as an important tool to help companies as well as financing and licensing agencies, demonstrating the company's global commitment with such aspects. (author)

  13. Hospice Agencies

    Data.gov (United States)

    U.S. Department of Health & Human Services — A list of all Hospice Agencies that have been certified by Medicare. The list includes addresses, phone numbers, and date of original CMS certification, as well as...

  14. Development of a checklist of quality indicators for clinical trials in resource-limited countries: the French National Agency for Research on AIDS and Viral Hepatitis (ANRS) experience.

    Science.gov (United States)

    Hanna, Mina; Minga, Albert; Fao, Paulin; Borand, Laurence; Diouf, Assane; Mben, Jean-Marc; Gad, Rita R; Anglaret, Xavier; Bazin, Brigitte; Chene, Geneviève

    2013-04-01

    Since 1994, the French National Agency for Research on AIDS and Viral Hepatitis (ANRS) has funded research sites in resource-limited countries (RLCs). These sites implement research on human immunodeficiency virus (HIV) infection and Hepatitis C. In parallel, international regulations and recommendations for clinical trials have evolved and proliferated. However, little guidance exists on how these should be interpreted and applied within academic trials and in the context of RLCs. After developing a specific Ethical Charter for research in developing countries in 2002, ANRS developed a set of quality indicators (QIs) as a monitoring tool for assessing compliance to international guidelines. We describe here the development process, QIs adopted, and areas for improvement. In 2008, a group of experts was convened that included a researcher representing each ANRS site (Cote d'Ivoire, Senegal, Cameroun, Burkina Faso, Egypt, and Cambodia). Our structuring interaction development process combined evidence and expert opinion in two nominal group meetings to identify (1) clinical trial processes involved, (2) issues specific to RLCs in terms of Good Clinical Practice (GCP) and the application of ethical recommendations, and (3) checklists of QIs adapted to clinical trials conducted in RLCs. The trial process reviewed and proposed for RLCs was mostly similar to the one produced in wealthier countries. The scheme generated by our work group added two further processes: 'drug management' and 'biological investigations'. Specific issues regarding trial management in RLCs were therefore described for eight trial steps (1) protocol conception and seeking authorizations, (2) participant enrollment and follow-up, (3) site monitoring, (4) drug management, (5) biological investigations, (6) record management, (7) data management, and (8) site closeout. A total of 58 indicators were identified with at least one indicator for each trial process. Some trial activities require further

  15. Transformative Agency

    DEFF Research Database (Denmark)

    Majgaard, Klaus

    The purpose of this paper is to enhance the conceptual understanding of the mediatory relationship between paradoxes on an organizational and an individual level. It presents a concept of agency that comprises and mediates between a structural and individual pole. The constitution of this agency...... is achieved through narrative activity that oscillates between the poles and transforms paradoxes through the configuration of plots and metaphors. Empirical cases are introduced in order to illustrate the implications of this understanding....

  16. The Texts of the Agency's Relationship Agreements with Specialized Agencies

    International Nuclear Information System (INIS)

    1988-03-01

    The text of the relationship agreement with the Agency has concluded with the United Nations Industrial Development Organization, together with the protocol regarding its entry into force, is reproduced in this document for the information of all Members of the Agency. The agreement entered into force on 9 October 1987 pursuant to Article 10

  17. The texts of the Agency's relationship agreements with specialized agencies

    International Nuclear Information System (INIS)

    1988-03-01

    The text of the relationship agreement which the Agency has concluded with the United Nations Industrial Development Organization, together with the protocol regarding its entry into force is reproduced. The agreement entered into force on 9 October 1987

  18. National Emission Inventory (NEI)

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data exchange allows states to submit data to the US Environmental Protection Agency's National Emissions Inventory (NEI). NEI is a national database of air...

  19. 78 FR 962 - Agency Information Collection Activities

    Science.gov (United States)

    2013-01-07

    ... Records; and Standard Form 714: Financial Disclosure Report, which are directly related to... OFFICE OF THE DIRECTOR OF NATIONAL INTELLIGENCE Agency Information Collection Activities AGENCY... ODNI accepted responsibility from the Information Security Oversight Office for the maintenance of...

  20. The Incorporation of Agencies in Colombia’s National Administrative Structure: An Axiological Comparison between Two Organizational Models of Public Administration

    Directory of Open Access Journals (Sweden)

    Alberto Montaña

    2015-06-01

    Full Text Available The incorporation of agencies into Colombia’s Administrative Structure has generated profound debates about the need to create administrative bodies that differ from traditional ones. Such incorporation is all the more problematic when these North American agencies are introduced without any real analysis of the local tradition and culture. The situation became more complicated as a consequence of the undisputed fact that the values and philosophies of the Public Administration Structure in Colombia are different from the predominant values in the United States. Hence, this paper provides a critical analysis of the institution and of its credulous and impulsive adoption of such instruments into our reality. 

  1. Enhancing national Daily Landslide Hazard Assessments through inter-agency collaboration; lessons learned from storm Desmond (UK)/Synne (Norway), Dec 2015.

    Science.gov (United States)

    Boje, Søren; Devoli, Graziella; Sund, Monica; Freeborough, Katy; Dijkstra, Tom; Reeves, Helen; Banks, Vanessa

    2016-04-01

    The Norwegian Water Resources and Energy Directorate (NVE) and the British Geological Survey (BGS) compile daily landslide hazard assessments (DLHA) in their respective countries. NVE DLHA has been operational since 2013 and provides national daily assessments based on quantitative thresholds related to daily hydro-meteorological forecasts coupled with qualitative expert analysis of these forecasts. The BGS DLHA has been operational since 2012 and this is predominantly based on expert evaluation of antecedent hydro-meteorological conditions and triggering rainfall across Great Britain (GB). In both cases, the hydro-meteorological evaluation is coupled with observations derived from proprietary datasets on landslide events and landslide potential in order to specify, and limit, the spatial extent of the potentially impacted area. However, the DLHA are strongly driven by hydro-meteorological forecasts. In December 2015, a large extra-tropical cyclone developed over the Atlantic and delivered record-breaking precipitation over parts of the UK and Norway. The meteorological services started naming these events to enhance public uptake and awareness and the storms were named as Desmond (the 4th large storm in 2015/16 in the UK) and Synne (the 5th storm in 2015 in Norway). Desmond arrived in earnest on the 5th of December and brought intense precipitation and strong winds over a 48-hour period. In Cumbria (NW-England) record precipitation was measured (341.4 mm in 24-hour at Honister Pass which is more than twice the monthly average), with 48-hour accumulations exceeding 400 mm. Synne arrived shortly after in Norway and was also characterised by excessive rainfall of 140 mm in 24-hour, 236 mm in 48-hour and 299 mm in 72-hour at Maudal, SW-Norway. Both organisations managed to issue appropriate advance warnings, operating individually. In Norway, warnings were issued some 2 days in advance with a yellow level communicated on Friday 4th and an orange warning the 5th and 6

  2. Molecular insights into a molluscan transferrin homolog identified from disk abalone (Haliotis discus discus) evidencing its detectable role in host antibacterial defense.

    Science.gov (United States)

    Herath, H M L P B; Elvitigala, Don Anushka Sandaruwan; Godahewa, G I; Whang, Ilson; Lee, Jehee

    2015-11-01

    The basic function of transferrin is to bind iron (III) ions in the medium and to deliver them to the locations where they are required for metabolic processes. It also takes part in the host immune defense mainly via its ability to bind to iron (III) ions. Hence, transferrin is also identified as an important acute-phase protein in host immunity. Abalones are major shellfish aquaculture crops that are susceptible to a range of marine microbial infections. Since transferrin is known to be a major player in innate immunity, in the present study we sought to identify, and molecularly and functionally characterize a transferrin-like gene from disk abalone (Haliotis discus discus) named as AbTrf. AbTrf consisted of a 2187-bp open reading frame (ORF) which encodes a 728 amino acid (aa) protein. The putative amino acid sequence of AbTrf harbored N- and C-terminal transferrin-like domains, active sites for iron binding, and conserved cysteine residues. A constitutive tissue specific AbTrf expression pattern was detected by qPCR in abalones where mantle and muscle showed high AbTrf expression levels. Three immune challenge experiments were conducted using Vibrio parahaemolyticus, Listeria monocytogenes and LPS as stimuli and, subsequently, AbTrf mRNA expression levels were quantified in gill and hemocytes in a time-course manner. The mRNA expression was greatly induced in both tissues in response to both challenges. Evidencing the functional property of transferrins, recombinant AbTrf N-terminal domain (AbTrf-N) showed dose-dependent iron (III) binding activity detected by chrome azurol S (CAS) assay system. Moreover, recombinant AbTrf-N could significantly inhibit the growth of iron-dependent bacterium, Escherichia coli in a dose-dependent manner. However, AbTrf-N was unable to show any detectable bacteriostatic activity against iron-independent bacterium Lactobacillus plantarum (L. plantarum) even at its highest concentration. Collectively, our results suggest that Ab

  3. Emerging Inclusive Education in the United Nations Relief and Works Agency for Palestine Refugees in the Near East: A Review of the Literature

    Science.gov (United States)

    Rodriguez, Jacqueline A.; Dieker, Lisa A.

    2018-01-01

    For refugee children with disabilities, international agencies provide largely humanitarian assistance, including education. However, the obstacles associated with refugee existence can impede progress in the movement towards educating children with disabilities in inclusive settings. This literature review summarizes the historical progression…

  4. The Independence of the Media and Its Regulatory Agencies: Shedding new light on formal and actual independence against the national context

    NARCIS (Netherlands)

    Schultz, W.; Valcke, P.; Irion, K.

    2014-01-01

    Media independence is vital for democracies, and so is the independence of the regulatory bodies governing it. The Independence of the Media and its Regulatory Agencies explores the complex relationship between media governance and independence of media regulatory authorities within Europe, which

  5. Application of Novel Polymorphic Microsatellite Loci Identified in the Korean Pacific Abalone (Haliotis diversicolor supertexta (Haliotidae in the Genetic Characterization of Wild and Released Populations

    Directory of Open Access Journals (Sweden)

    Seong Wan Hong

    2012-08-01

    Full Text Available The small abalone, Haliotis diversicolor supertexta, of the family Haliotidae, is one of the most important species of marine shellfish in eastern Asia. Over the past few decades, this species has drastically declined in Korea. Thus, hatchery-bred seeds have been released into natural coastal areas to compensate for the reduced fishery resources. However, information on the genetic background of the small abalone is scarce. In this study, 20 polymorphic microsatellite DNA markers were identified using next-generation sequencing techniques and used to compare allelic variation between wild and released abalone populations in Korea. Using high-throughput genomic sequencing, a total of 1516 (2.26%; average length of 385 bp reads containing simple sequence repeats were obtained from 86,011 raw reads. Among the 99 loci screened, 28 amplified successfully, and 20 were polymorphic. When comparing allelic variation between wild and released abalone populations, a total of 243 different alleles were observed, with 18.7 alleles per locus. High genetic diversity (mean heterozygosity = 0.81; mean allelic number = 15.5 was observed in both populations. A statistical analysis of the fixation index (FST and analysis of molecular variance (AMOVA indicated limited genetic differences between the two populations (FST = 0.002, p > 0.05. Although no significant reductions in the genetic diversity were found in the released population compared with the wild population (p > 0.05, the genetic diversity parameters revealed that the seeds released for stock abundance had a different genetic composition. These differences are likely a result of hatchery selection and inbreeding. Additionally, all the primer pair sets were effectively amplified in another congeneric species, H. diversicolor diversicolor, indicating that these primers are useful for both abalone species. These microsatellite loci

  6. Teacher agency

    DEFF Research Database (Denmark)

    Priestley, M.; Biesta, G.; Robinson, Sarah

    2015-01-01

    ]turn to the centrality of the teacher in school-based curriculum development. In many cases, this renewed emphasis on teachers is explicitly tied to change agendas, with teachers described as agents of change. And yet such change agentry (Fullan, 2003) and teacher agency more broadly are often circumscribed by features...

  7. Disk abalone (Haliotis discus discus) expresses a novel antistasin-like serine protease inhibitor: Molecular cloning and immune response against bacterial infection.

    Science.gov (United States)

    Nikapitiya, Chamilani; De Zoysa, Mahanama; Oh, Chulhong; Lee, Youngdeuk; Ekanayake, Prashani Mudika; Whang, Ilson; Choi, Cheol Young; Lee, Jae-Seong; Lee, Jehee

    2010-04-01

    A novel antistasin-like cDNA homologue named as Ab-Antistasin was isolated from the disk abalone Haliotis discus discus normalized cDNA library. The Ab-Antistasin (1398-bp) consisted of an 1185-bp open reading frame encoding 395 amino acid (aa) residues. The predicted molecular mass and isoelectric point of Ab-Antistasin was 44 kDa and 8.5, respectively, and showed highest identity (23.1%) to Hydra magnipapillata antistasin. The most striking feature of Ab-Antistasin is the 12-fold internal repeats (IR) of an antistasin-like domain. Ten of the 12 IR domains (26-27 aa) are highly conserved, with 6 cysteines and 1 glycine. Ab-Antistasin was comprised of three Bowman-Birk serine protease inhibitor family motifs. The recombinant Ab-Antistasin (rAb-Antistasin) was over-expressed in Escherichia coli and purified using a pMAL system. rAb-Antistasin (10 microM) was able to inhibit trypsin activity by 66% in a dose-dependent manner. Moreover, it exhibited low prolongation activity for coagulation in an APTT assay (86.0 s compared to control 42.0 s) with human blood. Endogenous Ab-Antistasin mRNA was found to be expressed in digestive tract, hepatopancreas, hemocytes, abductor muscle and mantle, with highest expression levels in digestive tract followed by hepatopancreas and hemocytes. Quantitative real time PCR results revealed that Ab-Antistasin transcription was significantly induced at 3 h post-infection (p.i.) after challenged by a mixture of bacteria (Vibrio alginolyticus, Vibrio parahemolyticus, and Listeria monocytogenes) in the abalone digestive tract; in the hemocytes, induction occurred at 6 and 12 h. The results indicated that Ab-Antistasin could play an important role in the immune responses of mollusks. Copyright 2009 Elsevier Ltd. All rights reserved.

  8. Two variants of selenium-dependent glutathione peroxidase from the disk abalone Haliotis discus discus: Molecular characterization and immune responses to bacterial and viral stresses.

    Science.gov (United States)

    Bathige, S D N K; Umasuthan, Navaneethaiyer; Godahewa, G I; Thulasitha, William Shanthakumar; Whang, Ilson; Won, Seung Hwan; Kim, Chul; Lee, Jehee

    2015-08-01

    Glutathione peroxidase (GPx) is an essential member of the antioxidant systems of living organisms and may be involved in immune defense against pathogenic invasion. In the current study, two selenium-dependent glutathione peroxidases (AbSeGPxs) that shared 54.3% identity were identified from the disk abalone Haliotis discus discus. The open reading frames (ORFs) of AbSeGPx-a and AbSeGPx-b coded for 222 and 220 amino acids, respectively, with a characteristic selenocysteine residue encoded by an opal stop codon (TGA). The conserved selenocysteine insertion sequence (SECIS) element was predicted in the 3' untranslated region (UTR) of both isoforms, and they were found to form two stem-loop structures. Amino acid comparison and phylogenetic studies revealed that the AbSeGPxs were closely related to those in other mollusk species and were evolutionarily distinct from those of other taxonomic groups. The SYBR Green qPCR was employed in investigating the transcripts of AbSeGPxs. The expression of AbSeGPxs mRNA was examined in different embryonic developmental stages and differential expression patterns for AbSeGPx-a and AbSeGPx-b were noted. Meanwhile, the highest expression of AbSeGPxs was detected in the hepatopancreas of healthy adult animals. Next, transcriptional levels were profiled in hemocytes of adults to determine the immune responses of AbSeGPxs to microbial infections. The results revealed the significant up-regulation of AbSeGPx-a in a time-dependent manner after bacterial (Listeria monocytogenes and Vibrio parahaemolyticus) and viral (viral hemorrhagic septicemia virus) infections. Consequently, these findings indicate that AbSeGPx-a and AbSeGPx-b might be involved in the embryonic development of disk abalone and the regulation of immune defense system of adult animals. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Identification of a novel molluscan short-type peptidoglycan recognition protein in disk abalone (Haliotis discus discus) involved in host antibacterial defense.

    Science.gov (United States)

    Premachandra, H K A; Elvitigala, Don Anushka Sandaruwan; Whang, Ilson; Lee, Jehee

    2014-07-01

    Peptidoglycan recognition proteins (PGRPs) are a widely studied group of pattern recognition receptors found in invertebrate as well as vertebrate lineages, and are involved in bacterial pathogen sensing. However, in addition to this principal role, they can also function in multiple host defense processes, including cell phagocytosis and hydrolysis of peptidoglycans (PGNs). In this study, a novel invertebrate short-type PGRP was identified in disk abalone (Haliotis discus discus) designated as AbPGRP. The complete coding sequence of AbPGRP was 534 bp, encoding a 178-amino acid protein with a predicted molecular mass of 20 kDa. The AbPGRP gene had a bipartite arrangement consisting of two exons separated by a single intron. Homology analysis revealed that AbPGRP shares conserved features, including amino acid residues critical for substrate and ion binding as well as for its amidase activity, with homologs of other species. Phylogenetic analysis of AbPGRP revealed that it likely evolved from a common ancestor of invertebrates, having significant homology with other molluscan PGRPs. Recombinant AbPGRP exhibited detectable, dose-dependent PGN-hydrolyzing activity with the presence of Zn(2+), and strong antibacterial activity against Vibrio tapetis, consistent with the functional properties previously reported for PGRPs in other mollusks. Moreover, AbPGRP transcription was induced upon treatment of healthy abalones with bacterial peptidoglycan and lipopolysaccharide, although the expression profiles differed with treatment, suggesting a capacity for discriminating between bacterial pathogens through molecular pattern recognition. Collectively, the findings of this study indicate that AbPGRP is a true homolog of invertebrate PGRPs and likely plays an indispensable role in host immunity. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. First report on the gastropod proapoptotic AIF3 counterpart from disk abalone (Haliotis discus discus) deciphering its transcriptional modulation by induced pathogenic stress.

    Science.gov (United States)

    Elvitigala, Don Anushka Sandaruwan; Jayasooriya, R G P T; Whang, Ilson; Lee, Jehee

    2015-12-01

    Apoptosis inducing factor (AIF) is a flavoprotein that is involved in oxidative phosphorylation and induces apoptosis in eukaryotic cells. There are three isozymes of AIF that have been identified to date, designated as AIF1, AIF2, and AIF3; the human AIF3 is also known as an AIF-like protein (AIFL). This study aimed to identify and characterize a homologue of AIF3 from disk abalone (AbAIF3) that belongs to the phylum Mollusca. The open reading frame (ORF) of AbAIF3 is 1749 base pairs (bp) in length and encodes a protein of 583 amino acids, with a predicted molecular mass of 63.14 kDa. Based on our in-silico analysis, the AbAIF3 protein harbored the typical domain architecture as that of the known AIF family proteins, consisting of N-terminal Rieske and pyridine nucleotide-disulphide oxidoreductase domain. Comparative protein sequence analysis confirmed that AbAIF3 is a homolog of AIF3. Moreover, our phylogenetic analysis revealed that AbAIF3 had a close evolutionary relationship with the molluscan counterparts. Interestingly, AbAIF3 was shown to induce apoptosis in HEK293T cells using transfection assays followed by flow cytometric analysis. In addition, we found that AbAIF3 mRNA expression was ubiquitous in physiologically important tissues, and significantly modulated upon experimental immune stimulations in hemocytes. Collectively, our study illustrates the indispensable role of AbAIF3 in inducing apoptosis in disk abalones, which in turn might be involved in hosts' immune defense mechanisms against microbial infections. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Three novel clade B serine protease inhibitors from disk abalone, Haliotis discus discus: Molecular perspectives and responses to immune challenges and tissue injury.

    Science.gov (United States)

    Bathige, S D N K; Umasuthan, Navaneethaiyer; Godahewa, G I; Whang, Ilson; Kim, Chul; Park, Hae-Chul; Lee, Jehee

    2015-08-01

    Serine protease inhibitors (SERPINs) control cellular protease activity in order to maintain cellular homeostasis. The immune and inflammatory responses of invertebrate clade B SERPINs have not been widely reported. In the present study, three proteins with high similarity to clade B SERPINs, referred to as AbSERPIN-1, AbSERPIN-2 and AbSERPIN-3, were identified from disk abalone (Haliotis discus discus). While AbSERPIN-1 (399 aa) was of a typical size for this protein class, AbSERPIN-2 (506 aa) and AbSERPIN-3 (532 aa) were relatively larger. Bioinformatic analysis revealed the characteristic SERPIN domain in each AbSERPIN. In addition, the N-terminal region of both AbSERPIN-2 and AbSERPIN-3 contained a predicted low complexity region (LCR) and a signal peptide, suggesting that these proteins are secretory proteins and are, thus, novel peptides. Tertiary structural models of the AbSERPINs highlighted their structural and functional conservation. Ubiquitous expression of AbSERPIN transcripts was evaluated by quantitative real time PCR (qPCR) analysis in seven tissue types. AbSERPIN-1, AbSERPIN-2, and AbSERPIN-3 transcript levels were highest in mantle, hemocytes, and muscles, respectively. Temporal expression analysis revealed that AbSERPINs were significantly (P < 0.05) elevated in hemocytes during the early/middle stages following the injection of a bacterial pathogen (Vibrio parahaemolyticus or Listeria monocytogenes) or an immuno-stimulant (lipopolysaccharide). Moreover, mantle tissue injury led to significant changes in the temporal expression of AbSERPIN mRNA. Specifically, transcription of AbSERPIN-1 and AbSERPIN-3 was considerably up-regulated, while expression of AbSERPIN-2 was suppressed. These results suggest a potential role of AbSERPINs in response to pathogen invasion and tissue injury in disk abalone. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. 5 CFR Appendix B to Part 2641 - Agency Components for Purposes of 18 U.S.C. 207(c)

    Science.gov (United States)

    2010-01-01

    ... Development Administration. International Trade Administration. Minority Business Development Agency (formerly listed as Minority Business Development Administration). National Institute of Standards and Technology... Systems Agency. Defense Intelligence Agency. Defense Logistics Agency. Defense Threat Reduction Agency...

  13. State Arts Agency Fact Sheet: Support for Arts Education

    Science.gov (United States)

    Online Submission, 2015

    2015-01-01

    This national overview of state arts agency grants and services for arts education includes summary statistics and geographic distribution. The fact sheet uses data from Final Descriptive Reports of state arts agency grant-making activities submitted annually to the National Assembly of State Arts Agencies (NASAA) and the National Endowment for…

  14. Agency doctorates

    International Nuclear Information System (INIS)

    1970-01-01

    Staff members of the Agency working at the Seibersdorf laboratory are continuing to achieve high academic distinction. Two more - both Austrian - have now been awarded the degree of Doctor of Agriculture. Joachim Kramer, who is 26, graduated from the Hochschule fur Bodenkultur in 1967 with the degree of Diplom-Ingenieur and then started work in the plant breeding and genetics section of the laboratory under the direction of Dr. Knut Mikaelsen. The results of the research work he carried out were accepted as the subject of a thesis for which he has now been granted his doctorate. The doctoral promotion took place on 30 June, at a ceremony attended by Dr. Andre Finkelstein, Deputy Director General for Research and Isotopes. The subject of Dr. Kramer's thesis was a comprehensive study of the mutagenic effects of fast neutrons and gamma rays, and the influence of various modifying factors such as water content, oxygen and metabolic state of seeds at the time of irradiation. This work has contributed significantly to the understanding of the mechanisms by which these two types of ionizing radiation produce mutations in seeds. The knowledge gained will be of great importance in the efficient use of ionizing radiation in practical plant breeding. Paul Wassermann, who is 33 years old, joined the Agency in 1965. He, too, graduated from the Hochschule fur Bodenkultur as Diplom-Ingenieur in agriculture, having graduated with honours previously from the agricultural secondary school at Raumberg, Austria, in 1958. Dr. Wassermann's own words may be used to explain how he came to gain his doctorate. 'In October, 1966, I completed my studies at the Hochschule,' he writes. 'I was employed at the Agency laboratories in Seibersdorf, working in the plant and soils group. Encouraged by the interesting research which was performed there, a thesis entitled 'the Fate of Nitrogen in Submerged Rice Soils' was started, which finally led to the doctor's degree in Agriculture in June this year

  15. Order of the 10 january 2003 authorizing the national agency for the radioactive wastes management to follow the gaseous and liquid effluents release for the exploitation of the radioactive wastes storage center of the Manche; Arrete du 10 janvier 2003 autorisant l'Agence nationale pour la gestion des dechets radioactifs a poursuivre les rejets d'effluents gazeux et liquides pour l'exploitation du centre de stockage de dechets radioactifs de la Manche

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-01-01

    This document, took out from the Official Journal, is the law text relative to the order of the 10 january 2003 authorizing the national agency for the radioactive wastes management to follow the gaseous and liquid effluents release for the exploitation of the radioactive wastes storage center of the Manche. (A.L.B.)

  16. Promoting Learning by Inquiry Among Undergraduates in Soil Sciences: Scaffolding From Project-based Courses to Student-Staff Research Grants by the National Research Agency in Oman

    Science.gov (United States)

    Al-Ismaily, Said; Kacimov, Anvar; Al-Maktoumi, Ali

    2016-04-01

    Three strategies in a soil science undergraduate programme with inquiry-based learning (IBL) principles at Sultan Qaboos University, Oman, are presented. The first strategy scaffolds courses into three phases: with direct instructional guidance, structured IBL, and finally, guided to open IBL. The second strategy involves extra-curricular activities of undergraduates, viz. conducting workshops on soils for pupils in grades 7-9 with their teachers. The third strategy promotes the teaching-research nexus through collaboration between the undergraduates and faculty within a student-supporting, government-funded programme through 1-year long research grants of up to 5,500 US/project. The efficiency of the strategies was evaluated by students' evaluations of courses and instructors and questionnaire-based surveys. Statistics of students' responses in teaching evaluations of IBL courses showed a significantly higher level of satisfaction compared with regular courses taught in the department and college. In surveys of other constituencies of the program, viz. the secondary schools, more than 90% of respondents "agreed" or "strongly agreed" that they had learned new information/secrets about soils. The indicators of success in the third strategy are: winning a highly competitive grant and, moreover, earning an even more competitive annual national award for the best executed research project. The two top graduates of the IBL soil programme progressed into the MSc programme with the university and national scholarships. Key words: inquiry based learning, soil science undergraduate program, scaffold of courses, outreach activities, teaching-research nexus, evaluation of program's efficiency

  17. Managing Assets Of Agricultural Property Of The National Treasury In The Context Of State Aid Granted By The Agricultural Property Agency

    Directory of Open Access Journals (Sweden)

    Lizińska Wiesława

    2015-09-01

    Full Text Available This study covers the issue of activities of the Agricultural Property Agency in terms of state aid in the form of non-repayable financial aid, with the following specific objectives: determining the scale and diversity of state aid granted by the APA (including the local branch in Olsztyn, evaluating the current technical condition of some of the assets and their condition upon being handed over by the APA, determining their importance, main problems associated with resources which are taken over, identifying and assessing the importance of actions which encourage communes to take over property still held by the APA, assessing the scale and procedure of aid granted in the opinion of representatives of APA units. The article makes use of information obtained from the local branch of the APA in Olsztyn in the years 2003-2014. A direct survey among the entities was taken. The survey questionnaire was sent in 2014 to all communes (gminas of the Province (Voivodeship of Warmia and Mazury (116 units. Completed questionnaires were returned by 73 representatives of the communes. A total of PLN 327.1 million was allotted in the Agency’s financial plans for the program of non-repayable financial aid during the period from 2009 to 2014. Approximately 81.6% of PLN 164.4 million granted by the local branch of the APA in Olsztyn, was granted to units of the public finance sector. As was shown in the survey conducted among representatives of local governments, the interest of communes in taking over assets still held by2 the local branch of the APA in Olsztyn could be increased by limiting the number of tenants who do not pay the rent regularly and by increasing the amount of non-repayable financial aid. It is possible to carry out the latter action, but the former could prove to be extremely difficult.

  18. A bifunctional invertebrate-type lysozyme from the disk abalone, Haliotis discus discus: genome organization, transcriptional profiling and biological activities of recombinant protein.

    Science.gov (United States)

    Bathige, S D N K; Umasuthan, Navaneethaiyer; Kasthuri, Saranya Revathy; Whang, Ilson; Lim, Bong-Soo; Nam, Bo-Hye; Lee, Jehee

    2013-10-01

    Lysozyme is an important enzyme in the innate immune system that plays a vital role in fighting microbial infections. In the current study, we identified, cloned, and characterized a gene that encodes an invertebrate-type lysozyme from the disk abalone, Haliotis discus discus (abLysI). The full-length cDNA of abLysI consisted of 545 bp with an open reading frame of 393 bp that encodes 131 amino acids. The theoretical molecular mass of mature abLysI was 12.3 kDa with an isoelectric point of 8.03. Conserved features in other homologs, such as catalytic sites for lytic activity (Glu(30) and Asp(41)), isopeptidase activity (His(107)), and ten cysteine residues were identified in abLysI. Genomic sequence analysis with respect to its cDNA showed that abLysI was organized into four exons interrupted by three introns. Several immune-related transcription factor binding sites were discovered in the putative promoter region. Homology and phylogeny analysis of abLysI depicted high identity and closer proximity, respectively, with an annelid i-type lysozyme from Hirudo medicinalis, and indicated that abLysI is a novel molluscan i-type lysozyme. Tissue-specific expressional studies revealed that abLysI is mainly transcribed in hepatopancreas followed by mantle. In addition, abLysI mRNA expression was induced following bacterial (Vibrio parahaemolyticus and Listeria monocytogenes) and viral (viral hemorrhagic septicemia virus) challenges. Recombinantly expressed abLysI [(r)abLysI] demonstrated strong lytic activity against Micrococcus lysodeikticus, isopeptidase activity, and antibacterial activity against several Gram-positive and Gram-negative bacteria. Moreover, (r)abLysI showed optimum lytic activity at pH 4.0 and 60 °C, while exhibiting optimum isopeptidase activity at pH 7.0. Taken together, these results indicate that abLysI is potentially involved in immune responses of the disk abalone to protect it from invaders. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. The Perennial Environment Observatory by A.N.D.R.A. (the French National Radioactive Waste Management Agency); L'Observatoire Perenne de l'Environnement ANDRA

    Energy Technology Data Exchange (ETDEWEB)

    Leclerc, E. [Agence Nationale pour la Gestion des Dechets Radioactifs, Observation et surveillance de l' environnement, Direction scientifique - ANDRA, 92 - Chatenay Malabry (France)

    2010-06-15

    The Perennial Environment Observatory [Observatoire Perenne de l'Environnement - OPE] is a unique approach and infrastructure developed and implemented by ANDRA, the French National Radioactive Waste Management Agency, as part of its overall project of deep geological disposal for radioactive waste. Its current mission is to assess the initial state of the rural (forest, pasture, open-field and aquatic) environment, prior to repository construction. This will be followed in 2017 (pending construction authorizations) and for a period exceeding a century, by monitoring of any impact the repository may have on the environment. In addition to serving its own industrial purpose of environmental monitoring, ANDRA also opens the OPE approach, infrastructure and acquired knowledge (database...) to the scientific community to support further research on long term evolution of the environment subjected to natural and anthropogenic stresses, and to contribute to a better understanding of the interaction between the various compartments of the environment. (author)

  20. Statement to the 36th session of the General Conference of the International Atomic Energy Agency 21 September 1992; Statement to the 47th session of the United Nations General Assembly 21 October 1992

    International Nuclear Information System (INIS)

    Blix, H.

    1993-01-01

    IAEA Director General, Hans Blix, in his statements to the 47th session of the United Nations General Assembly and to the 36th session of the General Conference of the IAEA, reminded that 1992 marks the fiftieth anniversary of controlled nuclear fission and the thirty-fifth anniversary of the IAEA. He specially commented on the various measures taken during the past year to strengthen the IAEA's safeguards system as a part of the challenge to reduce the risk of a further spread of nuclear weapons. He also discussed the role of the IAEA in the fields of nuclear safety, nuclear waste, transfer of technology and assistance to developing countries and the financing and management of the Agency within the UN system

  1. The Agency's budget

    International Nuclear Information System (INIS)

    1964-01-01

    A total Agency Budget of $10 406 000 for 1965 was approved by the General Conference at its session of September 1964; the Budget for the year 1964 amounted to $9 812 000. The consolidated Budget figures are shown in the table at the end of this article. The Budget falls into two parts - the Regular Budget and the Operational Budget. The Regular Budget provides for the ordinary administrative expenses of the Agency, and for expert panels, special missions, symposia and conferences, distribution of information, and scientific and technical services. In conformity with the Agency's Statute, these expenses are met by contributions made according to Voluntary contributions are paid initially into a General Fund established for this purpose, and money for operations is transferred to the respective Operating Funds as appropriate, and as approved by the Board of Governors. The scale of assessments for 1965 is based on the United Nations scale for 1964. The assessments are estimated to yield $7 713 000 - an increase of 6.8 per cent; however, more than three quarters of this increase will be offset by credits which Member States will receive as a result of a cash surplus brought forward. The Operational Budget is financed by voluntary contributions and is divided into two parts - Operating Fund I, devoted to certain laboratory and research projects, and Operating Fund II, for technical assistance, training and research contracts.

  2. Computer Security Awareness Guide for Department of Energy Laboratories, Government Agencies, and others for use with Lawrence Livermore National Laboratory`s (LLNL): Computer security short subjects videos

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-31

    Lonnie Moore, the Computer Security Manager, CSSM/CPPM at Lawrence Livermore National Laboratory (LLNL) and Gale Warshawsky, the Coordinator for Computer Security Education & Awareness at LLNL, wanted to share topics such as computer ethics, software piracy, privacy issues, and protecting information in a format that would capture and hold an audience`s attention. Four Computer Security Short Subject videos were produced which ranged from 1-3 minutes each. These videos are very effective education and awareness tools that can be used to generate discussions about computer security concerns and good computing practices. Leaders may incorporate the Short Subjects into presentations. After talking about a subject area, one of the Short Subjects may be shown to highlight that subject matter. Another method for sharing them could be to show a Short Subject first and then lead a discussion about its topic. The cast of characters and a bit of information about their personalities in the LLNL Computer Security Short Subjects is included in this report.

  3. Actibacter haliotis sp. nov., isolated from the gut of an abalone, Haliotis discus hannai, and emended description of the genus Actibacter.

    Science.gov (United States)

    Hyun, Dong-Wook; Kim, Joon Yong; Kim, Min-Soo; Shin, Na-Ri; Kim, Hyun Sik; Lee, June-Young; Bae, Jin-Woo

    2015-01-01

    A novel strain, designated strain W113(T), was isolated from the gut of an abalone, Haliotis discus hannai, which was collected from the northern coast of Jeju in Korea. The isolate was a Gram-staining-negative, facultatively anaerobic, non-motile, rod-shaped bacterium producing yellow-to-orange carotenoid-type pigments. 16S rRNA gene sequence analysis showed that the isolate belonged to the genus Actibacter in the family Flavobacteriaceae and it shared the highest sequence similarity with the type strain of Actibacter sediminis (98.8 % similarity). Optimal growth occurred at 25 °C, at pH 7 and with 2 % (w/v) NaCl. The major cellular fatty acids were iso-C15:0, anteiso-C15:0 and iso-C15:1 G. Menaquinone-6 was the main respiratory quinone. The polar lipids of the isolate were phosphatidylethanolamine, three unidentified amino lipids, and three unidentified lipids. The genomic DNA G+C content was 42.6 mol% and DNA-DNA hybridization values indicated that the strain shared <18 % genomic relatedness with the most closely related species. The results of the phylogenetic, phenotypic and genotypic analyses indicated that strain W113(T) represents a novel species in the genus Actibacter, for which the name Actibacter haliotis sp. nov. is proposed. The type strain is W113(T) ( = KACC 17209(T) = JCM 18868(T)). © 2015 IUMS.

  4. Effect of air-temperature and diet composition on the drying process of pellets for japanese abalone (Haliotis discus hannai feeding

    Directory of Open Access Journals (Sweden)

    Antonio Vega-Gálvez

    2011-09-01

    Full Text Available The aim of this research was to study the effect of air-temperature and diet composition on the mass transfer kinetics during the drying process of pellets used for Japanese Abalone (Haliotis discus hannai feeding. In the experimental design, three temperatures were used for convective drying, as well as three different diet compositions (Diets A, B and C, in which the amount of fishmeal, spirulin, algae, fish oil and cornstarch varied. The water diffusion coefficient of the pellets was determined using the equation of Fick's second law, which resulted in values between 0.84-1.94×10-10 m²/s. The drying kinetics was modeled using Page, Modified Page, Root of time, Exponential, Logarithmic, Two-Terms, Modified Henderson-Pabis and Weibull models. In addition, two new models, referred to as 'Proposed' models 1 and 2, were used to simulate this process. According to the statistical tests applied, the models that best fitted the experimental data were Modified Henderson-Pabis, Weibull and Proposed model 2, respectively. Bifactorial analysis of variance ANOVA showed that Diet A (fishmeal 44%, spirulin 9%, fish oil 1% and cornstarch 36% presented the highest diffusion coefficient values, which were favored by the temperature increase in the drying process.

  5. National Security Challenges: Insights from Social, Neurobiological, and Complexity Sciences. Topical Strategic Multi-Layer Assessment (SMA) and U.S. Army ERDC Multi-Agency/Multi-Disciplinary White Papers in Support of National Security Challenges

    Science.gov (United States)

    2012-07-01

    facing the infidel ” or “the life of a martyr.” Remember that norms are social constructions of shared beliefs, and as such are meaningless until a...other tribal section; my tribe against the other tribe; Muslims against infidels .” See also, for example, Montgomery McFate’s, “The “Memory of War...visual image, and this tendency emerges across four distinct domains: sexual , disgust, defense, National Security Challenges Approved for Public

  6. US energy agency making progress

    Science.gov (United States)

    2017-07-01

    The Advanced Research Projects Agency-Energy (ARPA-E) has the ability to make significant contributions to energy research but must be allowed time to do so, according to a report by the US National Academies of Sciences, Engineering and Medicine.

  7. Environmental Protection Agency, Office of Air and Radiation

    Science.gov (United States)

    ... 19, 2017 Web Snapshot . US EPA United States Environmental Protection Agency Search Search About EPA Contact Us ... Your UV Index Climate change National Analytical Radiation Environmental Laboratory National Vehicle and Fuel Emissions Laboratory National ...

  8. Geological disposal of radioactive wastes: national commitment, local and regional involvement. A Collective Statement of the OECD Nuclear Energy Agency 'Radioactive Waste Management Committee', adopted March 2011

    International Nuclear Information System (INIS)

    2012-01-01

    Disposal in engineered facilities built in stable, deep geological formations is the reference solution for permanently isolating long-lived radioactive waste from the human biosphere. This management method is designed to be intrinsically safe and final, i.e. not dependent on human presence and intervention in order to fulfil its safety goal. Siting waste repositories brings up a range of issues that touch on scientific knowledge, technical capacity, ethical values, territorial planning, community well-being, and more. Bringing to fruition the multi-decades task of siting and developing a repository demands a strong national commitment and a significant regional and local involvement. This Collective Statement by the Radioactive Waste Management Committee of the OECD Nuclear Energy Agency recognizes the advances made toward greater transparency and dialogue among the diverse relevant stakeholders and identifies the fundamental ingredients needed to support national commitment and foster territorial involvement. It concludes that technical and societal partners can develop shared confidence in the safety of geological repositories and jointly carry these projects forward

  9. A Novel Aldo-Keto Reductase, HdRed, from the Pacific Abalone Haliotis discus hannai, Which Reduces Alginate-derived 4-Deoxy-l-erythro-5-hexoseulose Uronic Acid to 2-Keto-3-deoxy-d-gluconate*

    Science.gov (United States)

    Mochizuki, Shogo; Nishiyama, Ryuji; Inoue, Akira; Ojima, Takao

    2015-01-01

    Abalone feeds on brown seaweeds and digests seaweeds' alginate with alginate lyases (EC 4.2.2.3). However, it has been unclear whether the end product of alginate lyases (i.e. unsaturated monouronate-derived 4-deoxy-l-erythro-5-hexoseulose uronic acid (DEH)) is assimilated by abalone itself, because DEH cannot be metabolized via the Embden-Meyerhof pathway of animals. Under these circumstances, we recently noticed the occurrence of an NADPH-dependent reductase, which reduced DEH to 2-keto-3-deoxy-d-gluconate, in hepatopancreas extract of the pacific abalone Haliotis discus hannai. In the present study, we characterized this enzyme to some extent. The DEH reductase, named HdRed in the present study, could be purified from the acetone-dried powder of hepatopancreas by ammonium sulfate fractionation followed by conventional column chromatographies. HdRed showed a single band of ∼40 kDa on SDS-PAGE and reduced DEH to 2-keto-3-deoxy-d-gluconate with an optimal temperature and pH at around 50 °C and 7.0, respectively. HdRed exhibited no appreciable activity toward 28 authentic compounds, including aldehyde, aldose, ketose, α-keto-acid, uronic acid, deoxy sugar, sugar alcohol, carboxylic acid, ketone, and ester. The amino acid sequence of 371 residues of HdRed deduced from the cDNA showed 18–60% identities to those of aldo-keto reductase (AKR) superfamily enzymes, such as human aldose reductase, halophilic bacterium reductase, and sea hare norsolorinic acid (a polyketide derivative) reductase-like protein. Catalytic residues and cofactor binding residues known in AKR superfamily enzymes were fairly well conserved in HdRed. Phylogenetic analysis for HdRed and AKR superfamily enzymes indicated that HdRed is an AKR belonging to a novel family. PMID:26555267

  10. A Novel Aldo-Keto Reductase, HdRed, from the Pacific Abalone Haliotis discus hannai, Which Reduces Alginate-derived 4-Deoxy-L-erythro-5-hexoseulose Uronic Acid to 2-Keto-3-deoxy-D-gluconate.

    Science.gov (United States)

    Mochizuki, Shogo; Nishiyama, Ryuji; Inoue, Akira; Ojima, Takao

    2015-12-25

    Abalone feeds on brown seaweeds and digests seaweeds' alginate with alginate lyases (EC 4.2.2.3). However, it has been unclear whether the end product of alginate lyases (i.e. unsaturated monouronate-derived 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH)) is assimilated by abalone itself, because DEH cannot be metabolized via the Embden-Meyerhof pathway of animals. Under these circumstances, we recently noticed the occurrence of an NADPH-dependent reductase, which reduced DEH to 2-keto-3-deoxy-D-gluconate, in hepatopancreas extract of the pacific abalone Haliotis discus hannai. In the present study, we characterized this enzyme to some extent. The DEH reductase, named HdRed in the present study, could be purified from the acetone-dried powder of hepatopancreas by ammonium sulfate fractionation followed by conventional column chromatographies. HdRed showed a single band of ∼ 40 kDa on SDS-PAGE and reduced DEH to 2-keto-3-deoxy-D-gluconate with an optimal temperature and pH at around 50 °C and 7.0, respectively. HdRed exhibited no appreciable activity toward 28 authentic compounds, including aldehyde, aldose, ketose, α-keto-acid, uronic acid, deoxy sugar, sugar alcohol, carboxylic acid, ketone, and ester. The amino acid sequence of 371 residues of HdRed deduced from the cDNA showed 18-60% identities to those of aldo-keto reductase (AKR) superfamily enzymes, such as human aldose reductase, halophilic bacterium reductase, and sea hare norsolorinic acid (a polyketide derivative) reductase-like protein. Catalytic residues and cofactor binding residues known in AKR superfamily enzymes were fairly well conserved in HdRed. Phylogenetic analysis for HdRed and AKR superfamily enzymes indicated that HdRed is an AKR belonging to a novel family. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  11. ANDRA - National Radioactive Waste Management Agency. Activity report 2009 - Managing today to prepare for tomorrow. Management report and financial statements at December 31, 2009. Annual Sustainable Development Report 2009

    International Nuclear Information System (INIS)

    2010-01-01

    Created in 1979 within the CEA, the National Radioactive Waste Management Agency (ANDRA) was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied; - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories. This mission includes as well a public service mission in terms of i) collection of waste of the 'small-scale nuclear activities' producers or owners (including the so-called 'household' radioactive waste, i.e. waste owned by private individuals) and ii) clean-up and rehabilitation of orphan polluted sites; - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This mission includes as well an active policy of dialogue with stakeholders both at national and local level. This document is the activity report, with the management and financial statements report, and the Sustainable Development Report of the Andra for the year 2009

  12. ANDRA - National Radioactive Waste Management Agency. Activity report 2008 - Fostering dialogue and outreach. Management report - Financial statements at December 31, 2008. Annual Sustainable Development Report 2008 - From strategy to initial actions: Andra's sustained commitment

    International Nuclear Information System (INIS)

    2009-06-01

    Created in 1979 within the CEA, the National Radioactive Waste Management Agency (ANDRA) was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied; - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories. This mission includes as well a public service mission in terms of i) collection of waste of the 'small-scale nuclear activities' producers or owners (including the so-called 'household' radioactive waste, i.e. waste owned by private individuals) and ii) clean-up and rehabilitation of orphan polluted sites; - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This mission includes as well an active policy of dialogue with stakeholders both at national and local level. This document is the activity report, with the management and financial statements report, and the Sustainable Development Report of the Andra for the year 2008

  13. Environmental Protection Agency

    Science.gov (United States)

    ... United States Environmental Protection Agency Search Search U.S. Environmental Protection Agency Contact Us Share It's Small Business ... WIFIA Tweets by @EPAScottPruitt View on Twitter U.S. Environmental Protection Agency Video Highlights It's Small Business Week ...

  14. Complications and Deaths - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — Complications and deaths - national data. This data set includes national-level data for the hip/knee complication measure, the Agency for Healthcare Research and...

  15. The Perspectives of the International Agencies

    Science.gov (United States)

    Hollander, Astrid

    2005-01-01

    An Inter-agency Panel of Technical and Vocational Education and Training (TVET) experts, drawn from seven United Nations and other international agencies, was one of the highlights in the programme of UNESCO's International Experts Meeting "Learning for Work, Citizenship and Sustainability" (Bonn, Germany, 25-28 October 2004). The Panel…

  16. Environmental Protection Agency - EPA Pub Central

    Data.gov (United States)

    U.S. Environmental Protection Agency — PubMed Central (PMC) is a full-text, online archive of journal literature operated by the National Library of Medicine. The EPA is using PMC to permanently preserve...

  17. Paraferrimonas haliotis sp. nov., isolated from the intestine of abalone, Haliotis discus hannai and emendation of description of the genus Paraferrimonas.

    Science.gov (United States)

    Huang, Jingran; Huang, Zhaobin; Shao, Zongze

    2017-12-01

    Two strains, AFRC7-2-1 T and CFD7-4-2, were isolated from the intestine of abalone, Haliotis discus hannai. The bacterial cells were Gram-stain-negative, stick-shaped and non-flagellated. They were facultative anaerobic bacteria and could reduce Fe(III) to Fe(II). The 16S rRNA genes of two strains shared 99.7 % sequence similarity, and had the highest similarity of 97.3-97.5 % with Paraferrimonas sedimenticola NBRC 101628 T , and of 5 %) of strains AFRC7-2-1 T and CFD7-4-2 were iso-C15 : 0, iso-C13 : 0, C14 : 0, C16 : 0, C17 : 1ω8c and summed feature 3 (C16 : 1ω7c/C16 : 1ω6c). The quinone system of strains AFRC7-2-1 T and CFD7-4-2 were quinone-8, menaquinone-6, menaquinone-7, and quinone-7. The predominant polar lipids of strain AFRC7-2-1 T were identified as phosphatidylethanolamine (PE), phosphatidylglycerol (PG), one unidentified phospholipid (PL), and three minor unidentified lipids (Ls). The genomic DNA G+C contents of two strains were 47.2 mol%. In summary, the two strains represented a novel species of the genus Paraferrimonas, for which the name Paraferrimonas haliotis sp. nov. was proposed, with type strain AFRC7-2-1 T (=MCCC 1A11748 T =KCTC 52632 T =NBRC 112785 T ) and strain CFD7-4-2 (=MCCC 1A11749=KCTC 52631=NBRC 112786).

  18. Antimicrobial and Antitumor Activities of Novel Peptides Derived from the Lipopolysaccharide- and β-1,3-Glucan Binding Protein of the Pacific Abalone Haliotis discus hannai.

    Science.gov (United States)

    Nam, Bo-Hye; Moon, Ji Young; Park, Eun Hee; Kong, Hee Jeong; Kim, Young-Ok; Kim, Dong-Gyun; Kim, Woo-Jin; An, Chul Min; Seo, Jung-Kil

    2016-12-14

    Antimicrobial peptides are a pivotal component of the invertebrate innate immune system. In this study, we identified a lipopolysaccharide- and β-1,3-glucan-binding protein (LGBP) gene from the pacific abalone Haliotis discus hannai (HDH), which is involved in the pattern recognition mechanism and plays avital role in the defense mechanism of invertebrates immune system. The HDH-LGBP cDNA consisted of a 1263-bp open reading frame (ORF) encoding a polypeptide of 420 amino acids, with a 20-amino-acid signal sequence. The molecular mass of the protein portion was 45.5 kDa, and the predicted isoelectric point of the mature protein was 4.93. Characteristic potential polysaccharide binding motif, glucanase motif, and β-glucan recognition motif were identified in the LGBP of HDH. We used its polysaccharide-binding motif sequence to design two novel antimicrobial peptide analogs (HDH-LGBP-A1 and HDH-LGBP-A2). By substituting a positively charged amino acid and amidation at the C -terminus, the pI and net charge of the HDH-LGBP increased, and the proteins formed an α-helical structure. The HDH-LGBP analogs exhibited antibacterial and antifungal activity, with minimal effective concentrations ranging from 0.008 to 2.2 μg/mL. Additionally, both were toxic against human cervix (HeLa), lung (A549), and colon (HCT 116) carcinoma cell lines but not much on human umbilical vein cell (HUVEC). Fluorescence-activated cell sorter (FACS) analysis showed that HDH-LGBP analogs disturb the cancer cell membrane and cause apoptotic cell death. These results suggest the use of HDH-LGBP analogs as multifunctional drugs.

  19. Real-time isothermal detection of Abalone herpes-like virus and red-spotted grouper nervous necrosis virus using recombinase polymerase amplification.

    Science.gov (United States)

    Gao, Fang; Jiang, Jing-Zhe; Wang, Jiang-Yong; Wei, Hong-Ying

    2018-01-01

    Abalone herpes-like virus (AbHV) and Red-spotted grouper nervous necrosis virus (RGNNV) are two serious viruses that infect animal populations in aquaculture. Both viruses cause diseases associated with high mortality rates, resulting in dramatic economic losses in the aquaculture industry. There are currently no effective treatments for either of these two viral diseases. Thus, early, rapid, and accurate diagnosis plays a fundamental role in disease prevention and control in aquaculture. Traditional methods of diagnosis, such as virus culture, enzyme-linked immunoassay, and polymerase chain reaction (PCR), are either time consuming or require sophisticated temperature control devices. In this study, one sets of specific primers and probes were designed for the real-time quantitative recombinase polymerase amplification (qRPA) detection of AbHV and RGNNV separately. The sensitivity and specificity of detection were evaluated by comparison with detection by conventional PCR and quantitative PCR. The optimal reaction temperature and time for virus detection is 37°C for 20min. The detection limit is 100 copies per reaction, making this approach faster and more sensitive than qPCR in this study. In a field application, the detection percentage of qRPA was higher than that of qPCR for both AbHV and NNV. Additionally, good correlation was found between qRPA and qPCR detection (R 2 >0.8). The methods presented here can be used as alternatives to qPCR for quick and quantitative detection of pathogens infecting aquaculture species. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. State Agencies of Special Nature in Colombia

    Directory of Open Access Journals (Sweden)

    María Clara Garrido

    2017-01-01

    Full Text Available With the latest reform of the Colombian Public Administration (2011 to 2013, the use of the term “National Agency” increases, in order to designate new administrative structures aimed to produce results and effectively manage public resources. Among the newly created administration, some structures were referred as “state agencies of special nature”, due to their alleged technical and specialized character. Through a comparison that encompasses functional and institutional aspects, this paper demonstrates that the expression “state agencies of special nature” does not establish a new category of public entities, different from other national agencies and administrative bodies listed in Act 489 of 1998.

  1. Joint Agency Commercial Imagery Evaluation (JACIE)

    Science.gov (United States)

    Jucht, Carrie

    2010-01-01

    Remote sensing data are vital to understanding the physical world and to answering many of its needs and problems. The United States Geological Survey's (USGS) Remote Sensing Technologies (RST) Project, working with its partners, is proud to sponsor the annual Joint Agency Commercial Imagery Evaluation (JACIE) Workshop to help understand the quality and usefulness of remote sensing data. The JACIE program was formed in 2001 to leverage U.S. Federal agency resources for the characterization of commercial remote sensing data. These agencies sponsor and co-chair JACIE: U.S. Geological Survey (USGS) National Aeronautics and Space Administration (NASA) National Geospatial-Intelligence Agency (NGA) U.S. Department of Agriculture (USDA) JACIE is an effort to coordinate data assessments between the participating agencies and partners and communicate the knowledge and results of the quality and utility of the remotely sensed data available for government and private use.

  2. News Agencies and Global Communication: Development ...

    African Journals Online (AJOL)

    they play in international communication. It argues that most of these roles have some consequences undesirable to the Third World Nations. Instead of facilitating the development of the poor nations of the world, the study reveals that the major news agencies by their worldwide operations are impeding the development of ...

  3. 78 FR 8192 - Agency Information Collection Activities: Comment Request; Education and Human Resources Project...

    Science.gov (United States)

    2013-02-05

    ... NATIONAL SCIENCE FOUNDATION Agency Information Collection Activities: Comment Request; Education and Human Resources Project Monitoring Clearance AGENCY: National Science Foundation. ACTION: Notice... study will assess the implementation of resources, models, and technologies to determine how and why...

  4. Home Health Care Agencies

    Data.gov (United States)

    U.S. Department of Health & Human Services — A list of all Home Health Agencies that have been registered with Medicare. The list includes addresses, phone numbers, and quality measure ratings for each agency.

  5. Technical Agency in Practice

    DEFF Research Database (Denmark)

    Krummheuer, Antonia Lina

    2015-01-01

    ) description of hybrid networks in which human and non-human actants are granted agency without differentiating different kinds of agency, EMCA focuses on the member's perspectives and the situated construction of technical agency that is made relevant within an ongoing interaction. Based on an EMCA analysis......The paper combines the discussion of technical agency and hybrid networks of Actor-Network Theory (ANT) with an ethnomethodological/conversation analytical (EMCA) perspective on situated practices in which participants ascribe agency to technical artefacts. While ANT works with (ethnographic...... of three video recordings of situations in which technical agency is made relevant by the human participants, the paper demonstrates different ways in which agency is granted to technical artefacts. Human participants can treat a technology as communication partner, as an active part (and actant...

  6. 14 CFR 223.5 - Responsibility of agencies.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Responsibility of agencies. 223.5 Section... PROCEEDINGS) ECONOMIC REGULATIONS FREE AND REDUCED-RATE TRANSPORTATION General Provisions § 223.5 Responsibility of agencies. The Federal Aviation Administration, National Transportation Safety Board, National...

  7. Understanding social media program usage in public transit agencies

    OpenAIRE

    Liu, Jenny H.; Shi, Wei; Elrahman, O.A. (Sam); Ban, Xuegang (Jeff); Reilly, Jack M.

    2016-01-01

    Social media has been gaining prominence in public transit agencies in their communication strategies and daily management. This study aims to better understand recent trends in social media usage in public transit agencies, to examine which agencies use what kind of social media programs for what purposes, and how they measure their programs. A survey was conducted of the top transit agencies in the nation, and results are examined through descriptive statistical analysis, correlation analys...

  8. Statement of Agreements Registered With The Agency

    International Nuclear Information System (INIS)

    1960-01-01

    This document contains a statement of all the agreements which had been registered with the Agency by 30 June 1960 under the Regulations for the Registration of Agreements adopted by the Board of Governors in implementation of Article XXII. B of the Statute. In compliance with Article VI of the Regulations this statement is hereby transmitted to all Members of the Agency for their information. A copy is also being sent to the Secretary-General of the United Nations

  9. Decree no. 2003-30 of the 10 january 2003 authorizing the national agency for the radioactive wastes management (ANDRA) to modify, for the survey step, the radioactive wastes storage center of the Manche (base nuclear installation no. 66), located on the Digulleville municipality territory (Manche)

    International Nuclear Information System (INIS)

    2003-01-01

    This document, took out from the Official Journal, is the law text relative to the decree no. 2003-30 of the 10 january 2003 authorizing the national agency for the radioactive wastes management (ANDRA) to modify, for the survey step, the radioactive wastes storage center of the Manche (base nuclear installation no. 66), located on the Digulleville municipality territory (Manche). (A.L.B.)

  10. Global, regional, and national levels and trends in under-5 mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Inter-agency Group for Child Mortality Estimation.

    Science.gov (United States)

    You, Danzhen; Hug, Lucia; Ejdemyr, Simon; Idele, Priscila; Hogan, Daniel; Mathers, Colin; Gerland, Patrick; New, Jin Rou; Alkema, Leontine

    2015-12-05

    In 2000, world leaders agreed on the Millennium Development Goals (MDGs). MDG 4 called for a two-thirds reduction in the under-5 mortality rate between 1990 and 2015. We aimed to estimate levels and trends in under-5 mortality for 195 countries from 1990 to 2015 to assess MDG 4 achievement and then intended to project how various post-2015 targets and observed rates of change will affect the burden of under-5 deaths from 2016 to 2030. We updated the UN Inter-agency Group for Child Mortality Estimation (UN IGME) database with 5700 country-year datapoints. As of July, 2015, the database contains about 17 000 country-year datapoints for mortality of children younger than 5 years for 195 countries, and includes all available nationally-representative data from vital registration systems, population censuses, household surveys, and sample registration systems. We used these data to generate estimates, with uncertainty intervals, of under-5 (age 0-4 years) mortality using a Bayesian B-spline bias-reduction model (B3 model). This model includes a data model to adjust for systematic biases associated with different types of data sources. To provide insights into the global and regional burden of under-5 deaths associated with post-2015 targets, we constructed five scenario-based projections for under-5 mortality from 2016 to 2030 and estimated national, regional, and global under-5 mortality rates up to 2030 for each scenario. The global under-5 mortality rate has fallen from 90·6 deaths per 1000 livebirths (90% uncertainty interval 89·3-92·2) in 1990 to 42·5 (40·9-45·6) in 2015. During the same period, the annual number of under-5 deaths worldwide dropped from 12·7 million (12·6 million-13·0 million) to 5·9 million (5·7 million-6·4 million). The global under-5 mortality rate reduced by 53% (50-55%) in the past 25 years and therefore missed the MDG 4 target. Based on point estimates, two regions-east Asia and the Pacific, and Latin America and the Caribbean

  11. Global, regional, and national levels and trends in maternal mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Maternal Mortality Estimation Inter-Agency Group.

    Science.gov (United States)

    Alkema, Leontine; Chou, Doris; Hogan, Daniel; Zhang, Sanqian; Moller, Ann-Beth; Gemmill, Alison; Fat, Doris Ma; Boerma, Ties; Temmerman, Marleen; Mathers, Colin; Say, Lale

    2016-01-30

    Millennium Development Goal 5 calls for a 75% reduction in the maternal mortality ratio (MMR) between 1990 and 2015. We estimated levels and trends in maternal mortality for 183 countries to assess progress made. Based on MMR estimates for 2015, we constructed projections to show the requirements for the Sustainable Development Goal (SDG) of less than 70 maternal deaths per 100,000 livebirths globally by 2030. We updated the UN Maternal Mortality Estimation Inter-Agency Group (MMEIG) database with more than 200 additional records (vital statistics from civil registration systems, surveys, studies, or reports). We generated estimates of maternal mortality and related indicators with 80% uncertainty intervals (UIs) using a Bayesian model. The model combines the rate of change implied by a multilevel regression model with a time-series model to capture data-driven changes in country-specific MMRs, and includes a data model to adjust for systematic and random errors associated with different data sources. We had data for 171 of 183 countries. The global MMR fell from 385 deaths per 100,000 livebirths (80% UI 359-427) in 1990, to 216 (207-249) in 2015, corresponding to a relative decline of 43·9% (34·0-48·7), with 303,000 (291,000-349,000) maternal deaths worldwide in 2015. Regional progress in reducing the MMR since 1990 ranged from an annual rate of reduction of 1·8% (0·0-3·1) in the Caribbean to 5·0% (4·0-6·0) in eastern Asia. Regional MMRs for 2015 ranged from 12 deaths per 100,000 livebirths (11-14) for high-income regions to 546 (511-652) for sub-Saharan Africa. Accelerated progress will be needed to achieve the SDG goal; countries will need to reduce their MMRs at an annual rate of reduction of at least 7·5%. Despite global progress in reducing maternal mortality, immediate action is needed to meet the ambitious SDG 2030 target, and ultimately eliminate preventable maternal mortality. Although the rates of reduction that are needed to achieve country

  12. Institutional entrepreneurship and agency

    DEFF Research Database (Denmark)

    Weik, E.

    2011-01-01

    of collective entrepreneurship and institutional work to see if they can overcome these incongruities. I conclude that although they can remedy some of the problems, these notions run the risk of describing everything until they describe nothing. In order to limit and enable the entrepreneurship literature...... to discuss agency meaningfully, I argue, it needs to develop analytical frames of agency derived either from existing sociological theories or from further developing its own brand of agency theory. © 2011 Blackwell Publishing Ltd....

  13. ADVERTISING AGENCY MARKETING MANAGEMENT

    OpenAIRE

    Denis Kislov, Yevgenia Horobei

    2015-01-01

    Goal of the paper. The goal of this article is to define the nature, specific features and factors pertaining to the advertising agency marketing management. One of the tools is the use of non-standard approaches to management of advertising agencies, which under certain conditions makes it possible to improve the situation and to bring the agency to a new higher level as well as to improve the efficiency of its functioning in the conditions of transformational economy of Ukraine. Methodol...

  14. Staff Acquisition -- Agencies

    Data.gov (United States)

    Office of Personnel Management — Job vacancy and organizational information from customer agencies sufficient to provide requested services: examining, strategic staffing, recruitment and branding,...

  15. 78 FR 72060 - Chimney Rock National Monument Management Plan; San Juan National Forest; Colorado

    Science.gov (United States)

    2013-12-02

    ... Rock National Monument Management Plan; San Juan National Forest; Colorado AGENCY: Forest Service, USDA... and resources within Chimney Rock National Monument, designated by Presidential Proclamation on... Action The Presidential Proclamation establishing Chimney Rock National Monument (the Monument) requires...

  16. NAIP National Metadata

    Data.gov (United States)

    Farm Service Agency, Department of Agriculture — The NAIP National Metadata Map contains USGS Quarter Quad and NAIP Seamline boundaries for every year NAIP imagery has been collected. Clicking on the map also makes...

  17. National Assessment Database

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Assessment Database stores and tracks state water quality assessment decisions, Total Maximum Daily Loads (TMDLs) and other watershed plans designed to...

  18. National Emission Inventory

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Emission Inventory contains measured, modeled, and estimated data for emissions of all known source categories in the US (stationary sources, fires,...

  19. National Lakes Assessment Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Lakes Assessment (NLA) is a first-ever statistically-valid survey of the biological condition of lakes and reservoirs throughout the U.S. The U.S....

  20. National Privacy Research Strategy

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — On July 1, NITRD released the National Privacy Research Strategy. Research agencies across government participated in the development of the strategy, reviewing...

  1. National Recommended Water Quality Criteria

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Recommended Water Quality Criteria is a compilation of national recommended water quality criteria for the protection of aquatic life and human health...

  2. NEPmap (National Estuary Program Mapper)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The NEPmap is designed to provide information in context with National Estuary Program Study Areas. There are 28 National Estuary Programs (NEPs) in the U.S.that...

  3. 76 FR 9209 - Draft NOAA National Aquaculture Policy

    Science.gov (United States)

    2011-02-16

    ... Atmospheric Administration Draft NOAA National Aquaculture Policy and Draft DOC National Aquaculture Policy... National Aquaculture Policy AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION: Notice of availability of draft aquaculture policy...

  4. Three novel C1q domain containing proteins from the disk abalone Haliotis discus discus: Genomic organization and analysis of the transcriptional changes in response to bacterial pathogens.

    Science.gov (United States)

    Bathige, S D N K; Umasuthan, Navaneethaiyer; Jayasinghe, J D H E; Godahewa, G I; Park, Hae-Chul; Lee, Jehee

    2016-09-01

    The globular C1q (gC1q) domain containing proteins, commonly referred as C1q domain containing (C1qDC) proteins, are an essential family of proteins involved in various innate immune responses. In this study, three novel C1qDC proteins were identified from the disk abalone (Haliotis discus discus) transcriptome database and designated as AbC1qDC1, AbC1qDC2, and AbC1qDC3. The cDNA sequences of AbC1qDC1, AbC1qDC2, and AbC1qDC3 consisted of 807, 1305, and 660 bp open reading frames (ORFs) encoding 269, 435, and 220 amino acids (aa), respectively. Putative signal peptides and the N-terminal gC1q domain were identified in all three AbC1qDC proteins. An additional predicted motif region, known as the coiled coil region (CCR), was identified next to the signal sequence of AbC1qDC2. The genomic organization of the AbC1qDCs was determined using a bacterial artificial chromosome (BAC) library. It was found that the CDS of AbC1qDC1 was distributed among three exons, while the CDSs of AbC1qDC2 and AbC1qDC3 were distributed between two exons. Sequence analysis indicated that the AbC1qDC proteins shared <40% identity with other counterparts from different species. According to the neighbor-joining phylogenetic tree, the proteins were grouped within an invertebrate group with high evolutionary distances, which suggests that they are new members of the C1qDC family. Higher expression of AbC1qDC1 and AbC1qDC2 was detected in hepatopancreas, muscle, and mantle tissues compare to the other tissues analyzed, using reverse transcription, followed by quantitative real-time PCR (qPCR) using SYBR Green, whereas AbC1qDC3 was predominantly expressed in gill tissues, followed by muscles and the hepatopancreas. The temporal expression of AbC1qDC transcripts in gills after bacterial (Vibrio parahaemolyticus and Listeria monocytogenes) and lipopolysaccharide stimulation indicated that AbC1qDCs can be strongly induced by both Gram-negative and Gram-positive bacterial species with different

  5. Exhibition; Image display agency

    International Nuclear Information System (INIS)

    Normazlin Ismail

    2008-01-01

    This article touches on the role of Malaysian Nuclear Agency as nuclear research institutions to promote, develop and encourage the peaceful uses of nuclear technology in its agricultural, medical, manufacturing, industrial, health and environment for the development of the country running successfully. Maturity of Malaysian Nuclear Agency in dealing with nuclear technology that are very competitive and globalization cannot be denied. On this basis Malaysian Nuclear Agency was given the responsibility to strengthen the nuclear technology in Malaysia. One way is through an exhibition featuring the research, discoveries and new technology products of the nuclear technology. Through this exhibition is to promote the nuclear technology and introduce the image of the agency in the public eye. This article also states a number of exhibits entered by the Malaysian Nuclear Agency and achievements during the last exhibition. Authors hope that the exhibition can be intensified further in the future.

  6. Statement to the 33rd session of the General Conference of the International Atomic Energy Agency 25 September 1989. Statement to the 44th session of the United Nations General Assembly 25 October 1989

    International Nuclear Information System (INIS)

    Blix, H.

    1989-11-01

    The report briefly describes the environmental problem and the energy needs which form an essential background against which the nuclear power option must be considered. It also reviews the Agency's recent work in the fields of operational safety, waste disposal and the problem of radiation protection and the generally poor public understanding of this problem

  7. On Epistemic Agency

    DEFF Research Database (Denmark)

    Ahlström, Kristoffer

    Every time we act in an effort to attain our epistemic goals, we express our epistemic agency. The present study argues that a proper understanding of the actions and goals relevant to expressions of such agency can be used to make ameliorative recommendations about how the ways in which we actua...... it comes to our freedom to express epistemic agency, more is not always better. In fact, less is often so much more.......Every time we act in an effort to attain our epistemic goals, we express our epistemic agency. The present study argues that a proper understanding of the actions and goals relevant to expressions of such agency can be used to make ameliorative recommendations about how the ways in which we...... actually express our agency can be brought in line with how we should express our agency. More specifically, it is argued that the actions relevant to such expressions should be identified with the variety of actions characteristic of inquiry; that contrary to what has been maintained by recent pluralists...

  8. 75 FR 27552 - Announcement of the Board of Trustees for the National Environmental Education Foundation

    Science.gov (United States)

    2010-05-17

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9152-1] Announcement of the Board of Trustees for the National Environmental Education Foundation AGENCY: Environmental Protection Agency (EPA). ACTION: Notice; correction. SUMMARY: The Environmental Protection Agency published a document in the Federal Register of...

  9. 75 FR 55791 - National Environmental Justice Advisory Council; Notice of Charter Renewal

    Science.gov (United States)

    2010-09-14

    ... AGENCY National Environmental Justice Advisory Council; Notice of Charter Renewal AGENCY: Environmental Protection Agency. ACTION: Notice of Charter Renewal. The Charter for the Environmental Protection Agency's... include community engagement, science, regulatory development, and enforcement and compliance. Inquiries...

  10. The sense of agency

    DEFF Research Database (Denmark)

    Ritterband-Rosenbaum, Anina

    Imagine that you are reaching for a cup of coffee. You experience that you are moving and that you have control of the movement you are executing. This feeling of control of your own body and the movements it is performing is called the sense of agency. This thesis consists of four studies which...... investigate the sense of agency. The central aspect of the thesis work was to understand if brain lesioned children, diagnosed with hemiplegic Cerebral Palsy (CP), have an altered sense of agency, and if this different experience has an influence on the feeling of control of their movements and their actual...

  11. Autonomy of State Agencies

    DEFF Research Database (Denmark)

    Hansen, Morten Balle; Niklasson, Birgitta; Roness, Paul

    NPM-doctrines states that ideal-type agencies should have a high level of managerial autonomy, while being controlled through result-based control instruments, like performance contracts. In this article, the authors present a first preliminary attempt to comparatively analyze the autonomy of state...... agencies in four Nordic countries: Denmark, Finland, Norway and Sweden. By using survey data from more than 500 state agencies in the four countries, the article analyses whether there is indeed a Scandinavian style of autonomy and result control and assesses which structural, cultural, and environmental...

  12. Corporate Social Responsibility and Labor Agency

    DEFF Research Database (Denmark)

    Lund-Thomsen, Peter; Coe, Neil

    This article examines the circumstances under which CSR initiatives facilitate and/or constrain labor agency in GPNs. Using a case study of Nike’s CSR approach in the football manufacturing industry of Pakistan, we explore how the CSR measures advocated in a new, emerging policy paradigm on CSR i...... is significantly shaped by national-level contextual factors....

  13. 78 FR 35295 - Agency Information Collection Activities: Department of Homeland Security (DHS) Cybersecurity...

    Science.gov (United States)

    2013-06-12

    ... increased cyber threats across the Nation, the National Initiative for Cybersecurity Education (NICE... DEPARTMENT OF HOMELAND SECURITY Agency Information Collection Activities: Department of Homeland Security (DHS) Cybersecurity Education Office (CEO) National Initiative for Cybersecurity Careers and...

  14. 78 FR 57643 - Agency Information Collection Activities: Department of Homeland Security (DHS) Cybersecurity...

    Science.gov (United States)

    2013-09-19

    ... Cybersecurity Initiative (CNCI). In response to increased cyber threats across the Nation, the National... DEPARTMENT OF HOMELAND SECURITY Agency Information Collection Activities: Department of Homeland Security (DHS) Cybersecurity Education Office (CEO) National Initiative for Cybersecurity Careers and...

  15. Detecting Social Innovation agency

    DEFF Research Database (Denmark)

    Pel, Bonno; Dorland, Jens; Wittmayer, Julia

    2017-01-01

    Considering that it is important for the social innovation research field to confront its methodological challenges, this contribution addresses the challenge of choosing appropriate units of analysis. In processes of transformative social innovation, the agency is distributed and therefore...

  16. State Agency Administrative Boundaries

    Data.gov (United States)

    Kansas Data Access and Support Center — This database comprises 28 State agency boundaries and point of contact. The Kansas Geological Survey collected legal descriptions of the boundaries for various...

  17. Supernatural agency and forgiveness

    NARCIS (Netherlands)

    Nieuwboer, W.; Schie, H.T. van; Karremans, J.C.T.M.; Wigboldus, D.H.J.

    2015-01-01

    The present research examined the hypothesis that supernatural agency attributions underlie the relation between religion and forgiveness. In two experiments a priming procedure was used to make religious concepts temporarily more salient. In Experiment 1, a religion prime marginally enhanced

  18. International Atomic Energy Agency Annual Report 2012

    International Nuclear Information System (INIS)

    Article VI.J of the Agency's Statute requires the Board of Governors to submit 'an annual report to the General Conference concerning the affairs of the Agency and any projects approved by the Agency'. This report covers the period 1 January to 31 December 2012. - The IAEA Annual Report 2012 aims to summarize only the significant activities of the Agency during the year in question. The main part of the report, starting on page 17, generally follows the programme structure as given in The Agency's Programme and Budget 2012-2013 (GC(55)/5). - The introductory chapter, 'Overview', seeks to provide a thematic analysis of the Agency's activities within the context of notable developments during the year. More detailed information can be found in the latest editions of the Agency's Nuclear Safety Review, Nuclear Technology Review, Technical Cooperation Report and the Safeguards Statement for 2012 and Background to the Safeguards Statement. - Additional information covering various aspects of the Agency's programme is available, in electronic form only, on iaea.org, along with the Annual Report. - Except where indicated, all sums of money are expressed in United States dollars. - The designations employed and the presentation of material in this document do not imply the expression of any opinion whatsoever on the part of the Secretariat concerning the legal status of any country or territory or of its authorities, or concerning the delimitation of its frontiers. - The mention of names of specific companies or products (whether or not indicated as registered) does not imply any intention to infringe proprietary rights, nor should it be construed as an endorsement or recommendation on the part of the Agency. - The term 'non-nuclear-weapon State' is used as in the Final Document of the 1968 Conference of Non- Nuclear-Weapon States (United Nations document A/7277) and in the Treaty on the Non-Proliferation of Nuclear Weapons (NPT). The term 'nuclear-weapon State' is as used

  19. International Atomic Energy Agency Annual Report 2012

    International Nuclear Information System (INIS)

    2013-01-01

    Article VI.J of the Agency's Statute requires the Board of Governors to submit 'an annual report to the General Conference concerning the affairs of the Agency and any projects approved by the Agency'. This report covers the period 1 January to 31 December 2012. - The IAEA Annual Report 2012 aims to summarize only the significant activities of the Agency during the year in question. The main part of the report, starting on page 17, generally follows the programme structure as given in The Agency's Programme and Budget 2012-2013 (GC(55)/5). - The introductory chapter, 'Overview', seeks to provide a thematic analysis of the Agency's activities within the context of notable developments during the year. More detailed information can be found in the latest editions of the Agency's Nuclear Safety Review, Nuclear Technology Review, Technical Cooperation Report and the Safeguards Statement for 2012 and Background to the Safeguards Statement. - Additional information covering various aspects of the Agency's programme is available, in electronic form only, on iaea.org, along with the Annual Report. - Except where indicated, all sums of money are expressed in United States dollars. - The designations employed and the presentation of material in this document do not imply the expression of any opinion whatsoever on the part of the Secretariat concerning the legal status of any country or territory or of its authorities, or concerning the delimitation of its frontiers. - The mention of names of specific companies or products (whether or not indicated as registered) does not imply any intention to infringe proprietary rights, nor should it be construed as an endorsement or recommendation on the part of the Agency. - The term 'non-nuclear-weapon State' is used as in the Final Document of the 1968 Conference of Non- Nuclear-Weapon States (United Nations document A/7277) and in the Treaty on the Non-Proliferation of Nuclear Weapons (NPT). The term 'nuclear-weapon State' is as used

  20. International Atomic Energy Agency Annual Report 2013

    International Nuclear Information System (INIS)

    2014-01-01

    Article VI.J of the Agency's Statute requires the Board of Governors to submit 'an annual report to the General Conference concerning the affairs of the Agency and any projects approved by the Agency'. This report covers the period 1 January to 31 December 2013. The IAEA Annual Report 2013 aims to summarize only the significant activities of the Agency during the year in question. The main part of the report, starting on page 15, generally follows the programme structure as given in The Agency's Programme and Budget 2012-2013 (GC(55)/5). The introductory chapter, 'The Year in Review', seeks to provide a thematic analysis of the Agency's activities within the context of notable developments during the year. More detailed information can be found in the latest editions of the Agency's Nuclear Safety Review, Nuclear Technology Review, Technical Cooperation Report and the Safeguards Statement for 2013 and Background to the Safeguards Statement. Additional information covering various aspects of the Agency's programme is available, in electronic form only, on iaea.org, along with the Annual Report. Except where indicated, all sums of money are expressed in United States dollars. The designations employed and the presentation of material in this document do not imply the expression of any opinion whatsoever on the part of the Secretariat concerning the legal status of any country or territory or of its authorities, or concerning the delimitation of its frontiers. The mention of names of specific companies or products (whether or not indicated as registered) does not imply any intention to infringe proprietary rights, nor should it be construed as an endorsement or recommendation on the part of the Agency. The term 'non-nuclear-weapon State' is used as in the Final Document of the 1968 Conference of Non-Nuclear- Weapon States (United Nations document A/7277) and in the Treaty on the Non-Proliferation of Nuclear Weapons (NPT). The term 'nuclear-weapon State' is as used in

  1. ADVERTISING AGENCY MARKETING MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Denis Kislov, Yevgenia Horobei

    2015-11-01

    Full Text Available Goal of the paper. The goal of this article is to define the nature, specific features and factors pertaining to the advertising agency marketing management. One of the tools is the use of non-standard approaches to management of advertising agencies, which under certain conditions makes it possible to improve the situation and to bring the agency to a new higher level as well as to improve the efficiency of its functioning in the conditions of transformational economy of Ukraine. Methodology. Monitoring of the marketing behavior of agencies that promote advertising services. The results of monitoring and analysis demonstrated that the majority of agencies have a disorganized approach to the agency marketing, which results in sporadic activities related to the use and organization of agency marketing. Only individual agencies begin to form their own marketing strategy for the implementation of which marketing budgets are allocated. The main marketing functions of a Ukrainian advertising agency have been identified. Practical value. Rapid development of technologies, sophistication and increased variety of goods and services, reduction of their life cycle, higher customer demands, the growth of volume and speed of obtaining information, increased competition – all these changes that are taking place in the external environment make the Ukrainian companies that provide advertising services search for new approaches to ensure better adaptation to these conditions. Uncertainty, unpredictability and instability of the external environment will continue to grow. Therefore, the companies that provide advertising services need to constantly adapt not only to the existing conditions but also ensure that they are able to quickly react in the future. The basic precondition for success is stability of the quality that is achieved through strategic planning, fine-tuned search system, efficient management, which encourages creation of a position of quality

  2. 75 FR 74062 - Agency Information Collection Activities; Proposed Collection; Comment Request; Exceptions or...

    Science.gov (United States)

    2010-11-30

    ... Strategic National Stockpile AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing an opportunity for public comment on the proposed... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Proposed...

  3. 76 FR 52991 - Agency Information Collection Activities: Proposed Collection; Comment Request

    Science.gov (United States)

    2011-08-24

    ... Records Administration (NARA) administers military service records of veterans after discharge, retirement... RECORDS ADMINISTRATION Agency Information Collection Activities: Proposed Collection; Comment Request AGENCY: National Archives and Records Administration (NARA). ACTION: Notice. SUMMARY: NARA is giving...

  4. A case study of enterprise historic resources information management in large transportation agencies.

    Science.gov (United States)

    2010-01-01

    Historic resources are in some way managed by every transportation agency in the nation. Transportation agencies manage historic and prehistoric archaeological sites, buildings, structures, objects, routes, landscapes, and districts to prevent damage...

  5. 17th and 18th March 2011 - Ukrainian Task Force led by Head, State Agency for Science, Innovation and Information Head V. Semynozhenko signing an agreement with CERN Director General R. Heuer witnessed by Ukrainian Ambassador to the Office of the United Nations M. Maimeskul.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    CERN-HI-1103091 tirage 29: from left to right: ALICE Collaboration, Bogolyubov Institute for Theoretical Physics (ITP) National Academy of Sciences of Ukraine,G Zinovjev; First Deputy Head of the State Agency on Science, Innovation and Information of Ukraine B. Grinyov Deputy Minister, Cabinet of Ministers of Ukraine Y. Avksentiev Ambassador Maimeskul to the UN; Delegation Head V. Semynozhenko; CERN Director-General R. Heuer; Head of International Relations F. Pauss; Director for Research S. Bertolucci; Adviser for Ukraine T. Kurtyka; Adviser for Non-Member States J. Ellis; Deputy Legal Counsel M. Wilbers.

  6. An invertebrate signal transducer and activator of transcription 5 (STAT5) ortholog from the disk abalone, Haliotis discus discus: Genomic structure, early developmental expression, and immune responses to bacterial and viral stresses.

    Science.gov (United States)

    Bathige, S D N K; Umasuthan, Navaneethaiyer; Park, Hae-Chul; Lee, Jehee

    2016-03-01

    Signal transducer and activator of transcription (STAT) family members are key signaling molecules that transduce cellular responses from the cell membrane to the nucleus upon Janus kinase (JAK) activation. Although seven STAT members have been reported in mammals, very limited information on STAT genes in molluscans is available. In this study, we identified and characterized a STAT paralog that is homologous to STAT5 from the disk abalone, Haliotis discus discus, and designated as AbSTAT5. Comparison of the deduced amino acid sequence for AbSTAT5 (790 amino acids) with other counterparts revealed conserved residues important for functions and typical domain regions, including the N-terminal domain, coiled-coil domain, DNA-binding domain, linker domain, and Src homology 2 (SH2) domains as mammalian counterparts. Analysis of STAT phylogeny revealed that AbSTAT5 was clustered with the molluscan subgroup in STAT5 clade with distinct evolution. According to the genomic structure of AbSTAT5, the coding sequence was distributed into 20 exons with 19 introns. Immunologically essential transcription factor-binding sites, such as GATA-1, HNF, SP1, C/EBP, Oct-1, AP1, c-Jun, and Sox-2, were predicted at the 5'-proximal region of AbSTAT5. Expression of AbSTAT5 mRNA was detected in different stages of embryonic development and observed at considerably higher levels in the morula and late veliger stages. Tissue-specific expressional studies revealed that the highest level of AbSTAT5 transcripts was detected in hemocytes, followed by gill tissues. Temporal expressions of AbSTAT5 were analyzed upon live bacterial (Vibrio parahemolyticus and Listeria monocytogenes), viral (viral hemorrhagic septicemia virus), and pathogen-associated molecular pattern (lipopolysaccharides and Poly I:C) stimulations, and significant elevations indicated immune modulation. These results suggest that AbSTAT5 may be involved in maintaining innate immune responses from developmental to adult stages in

  7. Agency Correspondence Tracking System (ACTS)

    Data.gov (United States)

    US Agency for International Development — Agency Correspondence Tracking System: is an executive correspondence tracking system for the Administrator. It collects and organizes information on reports...

  8. 24 CFR 214.305 - Agency profile changes.

    Science.gov (United States)

    2010-04-01

    ...) of its branches and affiliates; (2) Staff personnel responsible for the Housing Counseling program... URBAN DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES HOUSING COUNSELING PROGRAM Program Administration § 214.305 Agency profile changes. Participating agencies...

  9. 40 CFR 6.404 - Lead or cooperating agency.

    Science.gov (United States)

    2010-07-01

    ... IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT AND ASSESSING THE ENVIRONMENTAL EFFECTS ABROAD OF EPA ACTIONS Assessing the Environmental Effects Abroad of EPA Actions § 6.404 Lead or cooperating agency. (a... environmental documents in order to avoid duplication of resources. In working with a lead agency, EPA shall to...

  10. 20 CFR 638.540 - Cooperation with agencies and institutions.

    Science.gov (United States)

    2010-04-01

    ... LABOR JOB CORPS PROGRAM UNDER TITLE IV-B OF THE JOB TRAINING PARTNERSHIP ACT Center Operations § 638.540 Cooperation with agencies and institutions. The Job Corps Director shall develop guidelines for the national...

  11. Agency, Context and Meaning

    DEFF Research Database (Denmark)

    Folkmann, Mads Nygaard

    2014-01-01

    the nature and extension of design. Three fundamental approaches to understanding design from the perspective of the humanities will be proposed: 1) The question of agency in design, what the role and agency of design can be conceived as in human life, which can be met by the historical perspective of design...... constituents in design where the paper points to design philosophy as a framework for interests in aesthetic, ontological and phenomenological concerns in design. In the methodology of the paper, the approaches from the humanities offer frameworks for understanding the role and nature of design in terms...... of meaning formulation and cultural contexts and, by this, contest design. In reflecting the foundational ground of design in terms of its agency, contexts and meaning constituents, design and its questioning of meaning can be critically reframed....

  12. 76 FR 50441 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Science.gov (United States)

    2011-08-15

    ... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List: Deletion of the Sayreville Landfill Superfund Site AGENCY: Environmental Protection Agency... of Intent to Delete the Sayreville Landfill Superfund Site (Site) located in Borough of Sayreville...

  13. 76 FR 17658 - National Forum for State and Territorial Chief Executives (National Forum) Program Cooperative...

    Science.gov (United States)

    2011-03-30

    ... HUMAN SERVICES Health Resources and Services Administration National Forum for State and Territorial Chief Executives (National Forum) Program Cooperative Agreement AGENCY: Health Resources and Services... Forum for State and Territorial Chief Executives (National Forum) Program Cooperative Agreement. SUMMARY...

  14. 78 FR 69462 - National Nanotechnology Initiative Strategic Plan; National Science and Technology Council...

    Science.gov (United States)

    2013-11-19

    ... nanoscale level leads to a revolution in technology and industry that benefits society. The combined... OFFICE OF SCIENCE AND TECHNOLOGY POLICY OFFICE National Nanotechnology Initiative Strategic Plan; National Science and Technology Council; National Nanotechnology Coordination Office AGENCY: Executive...

  15. 75 FR 82037 - National Protection and Programs Directorate; President's National Security Telecommunications...

    Science.gov (United States)

    2010-12-29

    ... Directorate; President's National Security Telecommunications Advisory Committee AGENCY: National Protection... Committee Meeting. SUMMARY: The President's National Security Telecommunications Advisory Committee (NSTAC... telecommunications policy. The new NSTAC Chair, James Crowe, Chief Executive Officer (CEO), Level 3 Communications...

  16. 75 FR 6032 - National Contact Center; Submission for OMB Review; National Contact Center Customer Evaluation...

    Science.gov (United States)

    2010-02-05

    ... for OMB Review; National Contact Center Customer Evaluation Survey AGENCY: Citizen Services and... collection requirement regarding the National Contact Center customer evaluation survey. A request for public..., National Contact Center Customer Evaluation Survey, in all correspondence. FOR FURTHER INFORMATION CONTACT...

  17. 76 FR 81827 - Declassification of National Security Information

    Science.gov (United States)

    2011-12-29

    ... Declassification of National Security Information AGENCY: National Archives and Records Administration. ACTION... related to declassification of classified national security information in records transferred to NARA's..., Classified National Security Information, and its Implementing Directive. These changes include establishing...

  18. Agency in Tarot

    DEFF Research Database (Denmark)

    Elias, Camelia

    2011-01-01

    This essay looks at the cross between archetypal images and symbolic language as expressed in the iconography of tarot cards ranging from the Renaissance period to the turn of the 20th century. It is also an example of how the idea of agency can be both analyzed and applied simultaneously...

  19. Data and agency

    Directory of Open Access Journals (Sweden)

    Helen Kennedy

    2015-12-01

    Full Text Available This introduction to the special issue on data and agency argues that datafication should not only be understood as the process of collecting and analysing data about Internet users, but also as feeding such data back to users, enabling them to orient themselves in the world. It is important that debates about data power recognise that data is also generated, collected and analysed by alternative actors, enhancing rather than undermining the agency of the public. Developing this argument, we first make clear why and how the question of agency should be central to our engagement with data. Subsequently, we discuss how this question has been operationalized in the five contributions to this special issue, which empirically open up the study of alternative forms of datafication. Building on these contributions, we conclude that as data acquire new power, it is vital to explore the space for citizen agency in relation to data structures and to examine the practices of data work, as well as the people involved in these practices.

  20. Data and agency

    NARCIS (Netherlands)

    Kennedy, H.; Poell, T.; van Dijck, J.

    2015-01-01

    This introduction to the special issue on data and agency argues that datafication should not only be understood as the process of collecting and analysing data about Internet users, but also as feeding such data back to users, enabling them to orient themselves in the world. It is important that

  1. Youth Media and Agency

    Science.gov (United States)

    Hauge, Chelsey

    2014-01-01

    This article addresses how capacity is conceived of and understood in youth media/civic education programming, and how beliefs about agency, development, relationality and youth manifests in the discourses, programmes, and practices of organizations operating youth media programmes. Through attention to a youth media and development programme in…

  2. The Agency of Event

    DEFF Research Database (Denmark)

    Nicholas, Paul; Tamke, Martin; Riiber, Jacob

    2014-01-01

    This paper explores the notion of agency within event-based models. We present an event-based modeling approach that links interdependent generative, analytic and decision making sub-models within a system of exchange. Two case study projects demonstrate the underlying modeling concepts and metho...

  3. Statement to the 39th session of the General Conference of the International Atomic Energy Agency 18 September 1995. Statement to the 50th session of the United Nations General Assembly 1 November 1995

    International Nuclear Information System (INIS)

    Blix, H.

    1995-11-01

    In the Statement to the 39th Session of the General Conference of the IAEA main directions of IAEA activities for 1994 and plans for the future are outlined. In the Statement to the 50th Session of the United Nations General Assembly main achievements and challenges facing the international community in the field of IAEA competence are discussed

  4. Statement to the 38th session of the General Conference of the International Atomic Energy Agency 19 September 1994; Statement to the 49th session of the United Nations General Assemblies 17 October 1994

    International Nuclear Information System (INIS)

    Blix, H.

    1994-10-01

    The document reproduces the two statements of the IAEA Director General to the 38th Session of the General conference of the IAEA from 19 September 1994 and to the 49th Session of the United Nations General Assembly from 17 October 1994. A separate abstract was prepared for each statement

  5. The National Agency for the management of radioactive wastes (ANDRA). Specific report (articles L. 143-3 and R. 143-1 of the Code of financial courts). Years 2008 to 2013 (Update 2014) - December 2015

    International Nuclear Information System (INIS)

    2015-12-01

    After a recall of ANDRA's missions, a statement outlines the good financial situation of the Agency for the considered period. The report first describes the ANDRA's operation, its governance, its operation in project-mode, organisation and relationship with public bodies and authorities. The second part describes and analyses the various components of its management: human resources management, the purchasing function, taxation. The third part comments ANDRA's accounts and budget: quality of accounts and financial audit, accounting and financial analysis. The last part addresses ANDRA's activities: long-winded projects for future storage sites, storage centres, management of wastes of small producers outside electronuclear activity, missions of public service. An opinion on management is finally provided

  6. Aspen Characteristics - Klamath National Forest [ds369

    Data.gov (United States)

    California Natural Resource Agency — The database represents point locations and associated stand assessment data collected with known aspen stands in the Klamath National Forest, Siskiyou County,...

  7. Aspen Delineation - Inyo National Forest [ds366

    Data.gov (United States)

    California Natural Resource Agency — The database represents delineations of known aspen stands where aspen assessments were collected in the Inyo National Forest, Inyo County, California. The Inyo...

  8. White House Communications Agency

    National Research Council Canada - National Science Library

    Gimble, Thomas

    1995-01-01

    The Chairman, House Committee on Government Reform and Oversight; the Chairman, House Subcommittee on National Security, International Affairs, and Criminal Justice, Committee on Government Reform and Oversight...

  9. 76 FR 57 - Special Regulation: Areas of the National Park System, National Capital Region

    Science.gov (United States)

    2011-01-03

    ...: Areas of the National Park System, National Capital Region AGENCY: National Park Service, Interior... demonstrations and special events for the National Capital Region. This proposed rule would revise the definition..., Chief, Division of Park Programs, National Park Service, National Capital Region, 1100 Ohio Drive, SW...

  10. Research as relational agency

    DEFF Research Database (Denmark)

    Hasse, Cathrine

    2017-01-01

    technologies like iPads are not just educational tools helping teachers teach as books, blackboards and chalk. They are forceful agents with an agency tied to the fact that they are also persuasive signs of innovation and thus preferred by managers over more traditional means. The article discuss how...... the agency of iPads implemented in Danish schools challenged the implementation of a research based auxiliary artefact, the TECS-model, meant to help teachers managing teaching with iPads in Danish schools. Researchers had to develop a special sensitivity to the cultural force of all of these artefacts......Studying the impact of educational technologies ‘in the wild’ put new demands on researchers than when researchers are conducting experiments in a laboratory. When researchers work within institutional boundaries they cannot take for granted that all members engaged in institutional work share...

  11. The sense of agency

    DEFF Research Database (Denmark)

    Ritterband-Rosenbaum, Anina

    motor disabilities. Study I and II used non-invasive electrophysiological techniques (electroencephalography and transcranial magnetic stimulation) to investigate the underlying neural network which makes us capable of distinguishing between movements caused by ourselves and an external agent....... The results showed coupled activity between sensorimotor areas which seem to be important to establish the sense of agency. Study III is a behavioral study comparing a group of CP children with a group of typically developing children to explore if CP children show an altered sense of agency due...... to their sensorimotor and perceptual problems. The result showed that children with CP have a different perception of control, and that they attribute to a larger extend movements to themselves even though they were not responsible for them. Study IV looked at how an intensive motor, perceptual and cognitive training...

  12. International Atomic Energy Agency Annual Report 2010

    International Nuclear Information System (INIS)

    2011-01-01

    The Annual Report 2010 aims to summarize only the significant activities of the Agency during the year in question The main part of the report, starting on page 17, generally follows the programme structure as given in The Agency's Programme and Budget 2010-2011 (GC(53)/5). The introductory chapter, 'Overview', seeks to provide a thematic analysis of the Agency's activities within the context of notable developments during the year More detailed information can be found in the latest editions of the Agency's Nuclear Safety Review, Nuclear Technology Review, Technical Cooperation Report and the Safeguards Statement and Background to the Safeguards Statement and Summary. For the convenience of readers, these documents are available on the CD-ROM attached to the inside back cover of this report. Additional information covering various aspects of the Agency's programme is provided on the attached CD-ROM and is also available on the Agency's web site at http://www.iaea.org./Publications/ Reports/index.html. Except where indicated, all sums of money are expressed in United States dollars. The designations employed and the presentation of material in this report do not imply the expression of any opinion whatsoever on the part of the Secretariat concerning the legal status of any country or territory or of its authorities, or concerning the delimitation of its frontiers. The mention of names of specific companies or products (whether or not indicated as registered) does not imply any intention to infringe proprietary rights, nor should it be construed as an endorsement or recommendation on the part of the Agency. The term 'non-nuclear-weapon State' is used as in the Final Document of the 1968 Conference of Non-Nuclear-Weapon States (United Nations document A/7277) and in the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) The term 'nuclear weapon State' is as used in the NPT.

  13. 75 FR 1405 - National Park Service

    Science.gov (United States)

    2010-01-11

    ... DEPARTMENT OF THE INTERIOR National Park Service Agency: National Park Service, Interior. Action... Statement for the Jefferson National Expansion Memorial, Missouri. SUMMARY: Pursuant to Section 102(2)(C) of the National Environmental Policy Act of 1969, 42 U.S.C. 4332(2)(C), the National Park Service (NPS...

  14. Detecting Social Innovation agency

    DEFF Research Database (Denmark)

    Pel, Bonno; Dorland, Jens; Wittmayer, Julia

    2017-01-01

    Considering that it is important for the social innovation research field to confront its methodological challenges, this contribution addresses the challenge of choosing appropriate units of analysis. In processes of transformative social innovation, the agency is distributed and therefore...... fundamentally difficult to detect and ascribe. This contribution addresses the challenge to develop methodologies that are consistent with this relational ontology, critically evaluating the three main unit of analysis choices that guided an international comparison of 20 transnational SI networks...

  15. Nationalism in Stateless Nations

    DEFF Research Database (Denmark)

    Thomsen, Robert Chr.

    previously independent countries, are excellent examples of this. Building on theories of national identity-formation and nationalism, it traces the development of cultural and political nationalism, and changing images of the national self. With a focus on important fomenting factors and actors...

  16. The Texts of the Agency's Relationship Agreements with Specialized Agencies

    International Nuclear Information System (INIS)

    1960-01-01

    The texts of the relationship agreements which the Agency has concluded with the specialized agencies listed below, together with the respective protocols authenticating them, are reproduced in this document in the order which the agreements entered into force, for the information of all Members of the Agency

  17. The Texts of the Agency's Relationship Agreements with Specialized Agencies

    International Nuclear Information System (INIS)

    1960-01-01

    The texts of the relationship agreements which the Agency has concluded with the specialized agencies listed below, together with the respective protocols authenticating them, are reproduced in this document in the order which the agreements entered into force, for the information of all Members of the Agency [fr

  18. The Texts of the Agency's Relationship Agreements with Specialized Agencies

    International Nuclear Information System (INIS)

    1960-01-01

    The texts of the relationship agreements which the Agency has concluded with the specialized agencies listed below, together with the respective protocols authenticating them, are reproduced in this document in the order which the agreements entered into force, for the information of all Members of the Agency [es

  19. National Radiological Fixed Lab Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Radiological Fixed Laboratory Data Asset includes data produced in support of various clients such as other EPA offices, EPA Regional programs, DOE,...

  20. PTSD: National Center for PTSD

    Medline Plus

    Full Text Available ... Performance VA Plans, Budget, & Performance VA Center for Innovation (VACI) Agency Financial Report (AFR) Budget Submission Recovery Act Resources Business Congressional Affairs Jobs Benefits Booklet Data & Statistics VA Open Data VA App Store National Resource Directory Grants ...

  1. National Aquatic Resource Survey data

    Data.gov (United States)

    U.S. Environmental Protection Agency — Surface water monitoring data from national aquatic surveys (lakes, streams, rivers). This dataset is associated with the following publication: Stoddard , J., J....

  2. National CAHPS Hospice Survey data

    Data.gov (United States)

    U.S. Department of Health & Human Services — This data set contains the national average (mean) “top-box” scores of Medicare-certified hospice agencies on Consumer Assessment of Healthcare Providers and...

  3. National Flood Hazard Layer (NFHL)

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The National Flood Hazard Layer (NFHL) is a compilation of GIS data that comprises a nationwide digital Flood Insurance Rate Map. The GIS data and services are...

  4. National Greenhouse Gas Emission Inventory

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Greenhouse Gas Emission Inventory contains information on direct emissions of greenhouse gases as well as indirect or potential emissions of greenhouse...

  5. National Strategy to Secure Cyberspace

    National Research Council Canada - National Science Library

    Schwalm, Keith T

    2006-01-01

    ... of a national strategy for securing cyberspace. The approach explored the development of cyber technology strategies and programs related to the mission and roles of Homeland Security Advanced Research Projects Agency...

  6. 76 FR 34761 - Classified National Security Information

    Science.gov (United States)

    2011-06-14

    ... MARINE MAMMAL COMMISSION Classified National Security Information [Directive 11-01] AGENCY: Marine... Commission's (MMC) policy on classified information, as directed by Information Security Oversight Office... of Executive Order 13526, ``Classified National Security Information,'' and 32 CFR part 2001...

  7. Creating Quality Improvement Culture in Public Health Agencies

    Science.gov (United States)

    Mahanna, Elizabeth; Joly, Brenda; Zelek, Michael; Riley, William; Verma, Pooja; Fisher, Jessica Solomon

    2014-01-01

    Objectives. We conducted case studies of 10 agencies that participated in early quality improvement efforts. Methods. The agencies participated in a project conducted by the National Association of County and City Health Officials (2007–2008). Case study participants included health directors and quality improvement team leaders and members. We implemented multiple qualitative analysis processes, including cross-case analysis and logic modeling. We categorized agencies according to the extent to which they had developed a quality improvement culture. Results. Agencies were conducting informal quality improvement projects (n = 4), conducting formal quality improvement projects (n = 3), or creating a quality improvement culture (n = 4). Agencies conducting formal quality improvement and creating a quality improvement culture had leadership support for quality improvement, participated in national quality improvement initiatives, had a greater number of staff trained in quality improvement and quality improvement teams that met regularly with decision-making authority. Agencies conducting informal quality improvement were likely to report that accreditation is the major driver for quality improvement work. Agencies creating a quality improvement culture were more likely to have a history of evidence-based decision-making and use quality improvement to address emerging issues. Conclusions. Our findings support previous research and add the roles of national public health accreditation and emerging issues as factors in agencies’ ability to create and sustain a quality improvement culture. PMID:24228680

  8. 78 FR 22274 - Agency Information Collection Activities: Office of Biometric Identity Management (OBIM...

    Science.gov (United States)

    2013-04-15

    ... Homeland Security (DHS), National Protection and Programs Directorate (NPPD), Office of Biometric Identity... Security, National Protection and Programs Directorate, Office of Biometric Identity Management. Title... DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2013-0016] Agency Information Collection...

  9. 75 FR 57033 - Agency Information Collection Activities: Proposed Collection; Comment Request

    Science.gov (United States)

    2010-09-17

    ... Healthcare Research and Quality (AHRQ) to request that the Office of Management and Budget (OMB) approve the... DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Agency... of the National Guideline Clearinghouse The mission of the Agency for Healthcare Research and Quality...

  10. 36 CFR 1220.32 - What records management principles must agencies implement?

    Science.gov (United States)

    2010-07-01

    ... Responsibilities § 1220.32 What records management principles must agencies implement? Agencies must create and... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false What records management principles must agencies implement? 1220.32 Section 1220.32 Parks, Forests, and Public Property NATIONAL...

  11. The Agency's Safeguards System (1965)

    International Nuclear Information System (INIS)

    1965-01-01

    On 28 September 1965 the Board of Governors approved the Agency's revised safeguards system which is set forth in this document for the information of all Members. For ease of reference the revised system may be cited as 'The Agency's Safeguards System (1965)' to distinguish it from the original system - 'The Agency's Safeguards System (1961)'- and from the original system as extended to large reactor facilities - 'The Agency's Safeguards System (1961, as Extended in 1964)'

  12. 75 FR 5113 - National Park Service Concession Contracts; Implementation of Alternative Valuation for Leasehold...

    Science.gov (United States)

    2010-02-01

    ... DEPARTMENT OF THE INTERIOR National Park Service National Park Service Concession Contracts... Marina Proposed Concession Contract, Grand Teton National Park AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The National Park Service (NPS) is proposing, subject to consideration of public...

  13. National Register of Historic Places - National Geospatial Data Asset (NGDA) NPS National Register Dataset

    Data.gov (United States)

    Federal Geographic Data Committee — A current, accurate spatial representation of all historic properties listed on the National Register of Historic Places is of interest to Federal agencies, the...

  14. Nation/non-nation

    DEFF Research Database (Denmark)

    Sonnichsen, André; Gad, Ulrik Pram

    2008-01-01

    Is nationality the only way of organizing political community? Given the ubiquity of the national principle, one might think so. But, in practice, the national principle is constantly challenged by what can be termed non-national identities. This article looks at manners in which such deviating...... identities can be conceptualized, how contemporary European states have attempted to deal with them when they arise and to what extent non-national modes of organizing political community can point towards a challenge to the national principle itself. In its capacity as an introduction to the special issue...

  15. Conception of spent fuel and radioactive wastes management in Poland based on the results of the previous work performed in the frames of Governmental Strategic Programme realised under patronate of National Atomic Energy Agency

    International Nuclear Information System (INIS)

    Wlodarski, J.; Chwaszczewski, S.; Slizowski, K.; Frankowski, Z.

    1999-01-01

    About 300 cubic meters of solid and solidified radioactive wastes of low and medium activity are produced each year in Poland. Such materials, after processing, are stored in the Institute of Atomic Energy at Swierk or in the National Repository for Radioactive Wastes in Rozan. About 6000 spent fuel elements are temporarily stored in water pools at Swierk. Assumptions and strategy of future spent fuel and radioactive wastes management are presented taking into account operation of the first nuclear power plants (after 2010). Then Governmental Strategic Programme (GSP) for the year 1997-1999 concerning such topic is described and some results of the work performed in the frames of the GSP are given

  16. Agency Directionality and Staff Individuality.

    Science.gov (United States)

    Hurst, James C.; And Others

    Psychologists who choose work as members of counseling agencies are likely to experience some dissonance between what their individual interests and skills would have them do professionally and what they are asked to do as a staff member of the agency. Conversely, as a component of a larger institution or community, an agency's very existence may…

  17. O Uso da Mediação Administrativa na Solução de Conflitos pela Agência Nacional de Energia Elétrica / The use of administrative mediation in the settlement of disputes by the National Electric Energy Agency

    Directory of Open Access Journals (Sweden)

    Rodrigo Bandeira Silva Chaves

    2016-05-01

    Full Text Available Purpose – To present the complexity of factors that permeate the institutionalization of administrative mediation in the course of the National Electric Energy Agency - ANEEL. Methodology/approach/design – Expository and comparative approach was used, based on the analysis of the organizational structure and ANEEL regulations relating to its activity of administrative mediation, as well as other theoretical concepts and data that underlie this activity, besides the theory of regulation Responsive. Findings – The results confirmed the convenience of institutionalized administrative mediation in the ANEEL, as a way to prevent judicial conflicts among the many regulated entities, as well as providing tools for practice that favors the use of Responsive regulation by the Agency to give priority to dialogue in resolving disputes, before application of the regulatory penalties. Practical implications – Noteworthy are the benefits of administrative mediation at expanding the dialogue between the regulator and the regulated entities, the gradation of punitive regulatory process and the pacification of conflicts. Originality/value – This article is inserted in specific niche regulatory, administrative mediation conducted by ANEEL, knowledge rarely explored by other research, a fact that contributes to the legal discussion of this issue.

  18. The law for the establishment of Science and Technology Agency

    International Nuclear Information System (INIS)

    1979-01-01

    The law defines the scope and competence of business under the jurisdiction of the agency to establish the organization possible to carry out effectively the administrative work in charge. The agency is set up as an outside department of the Prime Minister's Office under the provisions of the law for the organization of state administration. Main tasks of the agency shall be to execute the administration of science and technology as a whole to develop them and help the progress of the national economy. Competences of the agency are provided for, such as: to make appropriations necessary for the business in charge in the extent of the budget; to collect incomes and pay expenses necessary for the business; to establish and control offices and other facilities directly necessary for the business; to appoint and remove the staff, etc. The agency is consisted of the secretariat and five bureaus of planning, research coordination, promotion, atomic energy and atomic energy safety. The functions of each department are prescribed in detail respectively. A science counselor is appointed, who assists the Director General in deciding important policies. The agency has its annexed organizations, including national aerospace laboratory, national research institutes for metals and radiological science, national research center for disaster prevention and others. (Okada, K.)

  19. The Role of Media in 'Knowledge Agency'

    Directory of Open Access Journals (Sweden)

    Manica Žmauc

    1996-12-01

    Full Text Available 'Knowledge Agency' is an information centre, which has been successfully connecting the offerers and searchers ofvarious knowledge and information for four years. The performance of the ser­ vice is basically dependent on the number of people included into the exchange of knowledge and information. This makes regular and flexible informing of the public one of the Agency's crucial activities. General public has to be informed on current educational offer and inquiry as well as on possibilities of mutual help. Therefore cooperation with various media is indespensible for the Agency. In the past three years the cooperation with some radio and television stations has been established as well as with some newspapers, publishing our information for free. The public is being informed also by means of dissemination of various information material. Also in the future, the Agency will only be able to meet the increasing needs of its users if its activities are supported by new information media, both on national and local

  20. 76 FR 77131 - Special Regulations; Areas of the National Park System, Yellowstone National Park

    Science.gov (United States)

    2011-12-12

    ... DEPARTMENT OF THE INTERIOR National Park Service 36 CFR Part 7 RIN 1024-AD92 Special Regulations; Areas of the National Park System, Yellowstone National Park AGENCY: National Park Service, Interior... National Park for the 2011-2012 winter season. The rule retains, for one additional year, the regulations...

  1. 77 FR 71018 - Agency Information Collection Activities; Extension of a Currently Approved Collection; Comment...

    Science.gov (United States)

    2012-11-28

    ...: National Youth Gang Survey AGENCY: Office of Juvenile Justice and Delinquency Prevention, Office of Justice... currently approved collection. 2. Title of the Form/Collection: National Youth Gang Survey. 3. Agency form.... Abstract: This collection will gather information related to youth and their activities for research and...

  2. 77 FR 1472 - Submission of Data by State Educational Agencies; Submission Dates for State Revenue and...

    Science.gov (United States)

    2012-01-10

    ... agencies (SEAs) of expenditure and revenue data and average daily attendance statistics on ED Form 2447... AGENCY: National Center for Education Statistics, Institute of Education Sciences, Department of.... Census Bureau is the data collection agent for the National Center for Education Statistics (NCES). The...

  3. 78 FR 7765 - Submission of Data by State Educational Agencies; Submission Dates for State Revenue and...

    Science.gov (United States)

    2013-02-04

    ... agencies (SEAs) of expenditure and revenue data and average daily attendance statistics on ED Form 2447... AGENCY: National Center for Education Statistics, Institute of Education Sciences, Department of.... Census Bureau is the data collection agent for the National Center for Education Statistics (NCES). The...

  4. 76 FR 10337 - National Advisory Council on Minority Business Enterprises; Meeting

    Science.gov (United States)

    2011-02-24

    ... minority businesses and their ability to successfully access the domestic and global marketplace. Topics to... DEPARTMENT OF COMMERCE Minority Business Development Agency National Advisory Council on Minority Business Enterprises; Meeting AGENCY: Minority Business Development Agency (MBDA), Department of Commerce...

  5. 76 FR 81915 - Proposed Information Collection; Comment Request; National Minority Enterprise Development (MED...

    Science.gov (United States)

    2011-12-29

    ... DEPARTMENT OF COMMERCE Minority Business Development Agency Proposed Information Collection; Comment Request; National Minority Enterprise Development (MED) Week Awards Program Requirements AGENCY: Minority Business Development Agency. ACTION: Notice. SUMMARY: The Department of Commerce, as part of its...

  6. 77 FR 3475 - National Advisory Council for Environmental Policy and Technology

    Science.gov (United States)

    2012-01-24

    ... help address environmental problems experienced by environmental justice communities and other... No: 2012-1527] ENVIRONMENTAL PROTECTION AGENCY [FRL-9622-4] National Advisory Council for Environmental Policy and Technology AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of advisory...

  7. Neuromodulation, agency and autonomy.

    Science.gov (United States)

    Glannon, Walter

    2014-01-01

    Neuromodulation consists in altering brain activity to restore mental and physical functions in individuals with neuropsychiatric disorders and brain and spinal cord injuries. This can be achieved by delivering electrical stimulation that excites or inhibits neural tissue, by using electrical signals in the brain to move computer cursors or robotic arms, or by displaying brain activity to subjects who regulate that activity by their own responses to it. As enabling prostheses, deep-brain stimulation and brain-computer interfaces (BCIs) are forms of extended embodiment that become integrated into the individual's conception of himself as an autonomous agent. In BCIs and neurofeedback, the success or failure of the techniques depends on the interaction between the learner and the trainer. The restoration of agency and autonomy through neuromodulation thus involves neurophysiological, psychological and social factors.

  8. Participation and agency

    DEFF Research Database (Denmark)

    Jamison, Andrew

    2003-01-01

    . The “environmental movement” has been effectively stripped of its underlying human meanings and motivations and instead transformed into institutions and professions; and the ideas of political ecology and the practices of appropriate technology have become a fragmented array of institutional, intellectual...... and practical activity, what I have termed the “making of green knowledge” (Jamison 2001). This paper is an attempt to explore some of the cultural dynamics of these transformation processes in terms of the human agency that have been involved in this multifarious shift in political agenda and practical focus.......In the course of the 1990s, the ideas and practices of environmentalism tended to lose whatever politically mobilizing force they might earlier have had, and largely came to resemble what Herbert Marcuse, in his classic text of the 1960s, termed the pure stuff of administration. The redefinition...

  9. 78 FR 8160 - President's National Security Telecommunications Advisory Committee

    Science.gov (United States)

    2013-02-05

    ... SECURITY President's National Security Telecommunications Advisory Committee AGENCY: National Protection... Committee Teleconference. SUMMARY: The President's National Security Telecommunications Advisory Committee... telecommunications policy. Agenda: The NSTAC members will review and discuss the draft NSTAC Report to the President...

  10. 78 FR 29145 - President's National Security Telecommunications Advisory Committee

    Science.gov (United States)

    2013-05-17

    ... DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2013-0022] President's National Security Telecommunications Advisory Committee AGENCY: National Protection and Programs Directorate, DHS. ACTION: Committee... notice of a May 22, 2013, meeting of the President's National Security Telecommunications Advisory...

  11. 78 FR 45255 - President's National Security Telecommunications Advisory Committee

    Science.gov (United States)

    2013-07-26

    ... Telecommunications Advisory Committee AGENCY: National Protection and Programs Directorate, DHS. [[Page 45256... President's National Security Telecommunications Advisory Committee (NSTAC) will meet on Tuesday, August 20... related to national security and emergency preparedness (NS/EP) telecommunications policy. Agenda: The...

  12. 75 FR 3913 - President's National Security Telecommunications Advisory Committee

    Science.gov (United States)

    2010-01-25

    ...] President's National Security Telecommunications Advisory Committee AGENCY: National Communications System... Telecommunications Advisory Committee (NSTAC) will be meeting by teleconference; the meeting will be open to the... implementing national security and emergency preparedness telecommunications policy. Notice of this meeting is...

  13. 78 FR 28237 - President's National Security Telecommunications Advisory Committee

    Science.gov (United States)

    2013-05-14

    ... Telecommunications Advisory Committee AGENCY: National Protection and Programs Directorate, DHS. ACTION: Committee... Security Telecommunications Advisory Committee (NSTAC) will meet on Wednesday, May 22, 2013, in Washington..., National Security Telecommunications Advisory Committee, National Protection and Programs Directorate...

  14. 77 FR 33443 - National Oceanic and Atmospheric Administration

    Science.gov (United States)

    2012-06-06

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration Pacific Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION: Notice of public meeting. SUMMARY: The panel to review assessment...

  15. Lessons learnt from stakeholder engagement in the UK Environment Agency

    International Nuclear Information System (INIS)

    Chandler, Steve

    2004-01-01

    The Environment Agency has many reasons and occasions for engaging with stakeholders and does so very frequently. Many of these are relatively formal, often statutory, consultations which are part of the determination of regulatory permits. Other consultations are part of the Agency's role as developer, for example in the construction of flood defence schemes. The Agency also consults nationally on its significant policies, such as the stocking of salmon fisheries. This paper gives some examples of lessons learnt from the Agency's own stakeholder engagements and also from our participation in those led by other organizations. In the next section it also describes the Agency's current approach to stakeholder consultation and engagement. (author)

  16. [Physician Involvement in the Activities of the European Medicines Agency].

    Science.gov (United States)

    Silva, Ivana

    2017-11-29

    For more than two decades of activity, the European Medicines Agency has been operating as part of a network with the national medicines agencies in Europe, bringing together - in its various scienti c committees and working groups - European experts on a wide range of topics related to quality assurance, safety and ef cacy of medicines. The work carried out within the European Medicines Agency activities and the conclusions reached at European level affect millions of citizens. The European Medicines Agency considers that it is of great importance to maintain, in a sustainable and consistent manner, the active participation of general practitioners, as well as other medical specialists, in the process of medicines' evaluation and supervision. This article summarizes how the participation of doctors and health professionals in general is promoted in the European Medicines Agency activities.

  17. David against Goliath - How creative communication helps small advertising agencies survive in a market led by giant agencies

    Directory of Open Access Journals (Sweden)

    Jenny - Maria Åström

    2017-09-01

    Full Text Available Purpose - The purpose of the study is to research how national advertising agencies use creativity to compete with larger, global agencies in the advertising market of Sweden, Spain and Portugal. Design/methodology/approach: To conduct the study, the authors keep a qualitative approach: we first carry out an analysis of previous studies about creativity, communication and entrepreneurial orientation, followed by interviews with one small and one large advertising agency for each country. Findings: The findings of the study show that smaller agencies have higher levels of competitive aggressiveness and risk - taking, because of the wish to expand and vulnerability to their larger clients. The levels of opportunity recognition are higher in the large agencies because of their resource assets. All agencies are creative and innovative and equally as proactive, but because the speed of the decision - making process can be faster and communication skills better in a small agency, they can reach higher levels of proactiveness. Research limitations/implications: The implications of the study show that the entrepreneurial orientation to some extent can be used by small agencies to gain competitive advantages on the advertising market. Originality/value: To the best of our knowledge there is no similar study available. This study showed that entrepreneurial orientation, to some extent, can be used by small agencies to gain competitive advantages in the advertising market.

  18. Combating hidden hunger: the role of international agencies.

    Science.gov (United States)

    Dalmiya, Nita; Schultink, Werner

    2003-12-01

    The importance of micronutrient deficiencies or "hidden hunger" was clearly emphasized by the inclusion of specific goals on iron, vitamin A, and iodine deficiency at the 1990 World Summit for Children and other major international nutrition conferences. Significant progress has since been made toward eliminating vitamin A and iodine deficiencies, with less progress made toward reducing the burden of iron-deficiency anemia. The role of international agencies, such as the World Health Organization, United Nations Children's Fund, Food and Agricultural Organization, and World Bank in assisting countries to make progress toward the World Summit for Children goals has been very important. International agencies have played a critical role in advocating for and raising awareness of these issues at the international, regional, and national levels among policymakers and the general population. Using a rights-based approach, UNICEF and other agencies have been instrumental in elevating to the highest political level the discussion of every child's right to adequate nutrition. International agencies have also been very supportive at the national level in providing technical guidance for programs, including monitoring and evaluation. These agencies have played a critical role in engaging the cooperation of other partners, including bilateral donors, non-governmental organizations, and the private sector for micronutrient programs. Furthermore, international agencies provide financial and material support for micronutrient programs. In the future, such agencies must continue to be heavily involved in programs to achieve the newly confirmed goals for 2010. The present paper focuses on the role of international agencies in combating micronutrient deficiencies, drawing on the lessons learned over the last decade. The first section of the paper summarizes the progress achieved since 1990, and the second section describes the specific role of international agencies in contributing

  19. 75 FR 12254 - National Park Service

    Science.gov (United States)

    2010-03-15

    ... DEPARTMENT OF THE INTERIOR National Park Service AGENCY: National Park Service, U.S. Department of... Training Board (PTTBoard) of the National Center for Preservation Technology and Training, National Park... Center's Sustainability and Preservation initiative; revitalization of the Friends of NCPTT; and training...

  20. 77 FR 2700 - National Advisory Council on Minority Business Enterprise: Meeting of the National Advisory...

    Science.gov (United States)

    2012-01-19

    ... Business Enterprise: Meeting of the National Advisory Council on Minority Business Enterprise AGENCY.... SUMMARY: The National Advisory Council for Minority Business Enterprise (NACMBE) will hold its fifth... deliberate on possible recommendations. The Subcommittee topics include: (1) Definition of Minority Business...

  1. National Health Insurance in South Africa: Relevance of a national ...

    African Journals Online (AJOL)

    National Health Insurance in South Africa: Relevance of a national priority-setting agency. Karen J Hofman, Shelley McGee, Kalipso Chalkidou, Sripen Tantivess, Anthony J Culyer. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  2. Nuclear Energy Agency

    International Nuclear Information System (INIS)

    2011-01-01

    The OECD Nuclear Energy Agency (NEA) was established on 1 February 1958 under the name of the OEEC European Nuclear Energy Agency. It received its present designation on 20 April 1972, when Japan became its first non-European full Member. Now, NEA membership consists of 28 OECD Member countries, i.e. Australia, Austria, Belgium, Canada, Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Japan, Luxembourg, Mexico, the Netherlands, Norway, Portugal, Republic of Korea, Spain, Sweden, Switzerland, Turkey, the United Kingdom and the United States of America. The NEA is the only intergovernmental nuclear energy organization which brings together developed countries of North America, Europe and the Asia-Pacific region in a small, non-political forum with a relatively narrow, technical focus. - NEA membership represents much of the world's best nuclear expertise; - By pooling this expertise, the NEA provides each Member access to the substantial experience of others and an opportunity to substantially leverage its resources in this field; - Homogeneity of NEA membership makes possible a like-minded approach to problems, a climate of mutual trust and collaboration, the full exchange of experience, and a frank assessment of issues; - The NEA is relatively unfettered by political and bureaucratic constraints, and is able to focus effectively on the specific needs of its Members; - NEA scientific and technical work is in the forefront of knowledge and is known for its depth; - The NEA publishes consensus positions on key issues, providing Member countries with credible references; - The NEA is cost effective. It operates with a small staff, relying on Member country experts, and provides significant added value; - The NEA's system of standing technical committees enables the Agency to be flexible and responsive; - NEA joint projects and information exchange programmes enable interested Members and non-members to join forces in carrying

  3. Agency costs and income taxation

    Directory of Open Access Journals (Sweden)

    Ulrich Schmidt

    2012-03-01

    Full Text Available This paper analyzes agency costs and the moral hazard problem in the presence of income taxation. As basic framework, income taxes are integrated in the hidden action model of agency theory. In the case of symmetric information no agency costs occur, i.e. optimal risk-sharing can be achieved, if and only if the tax is proportional. It is well-known that asymmetric information causes a welfare loss, termed agency costs, even if no taxes are imposed. Introducing a proportional income tax now increases (decreases these agency costs if the agent exhibits decreasing (increasing absolute risk aversion. Additionally, we show that non-proportional taxes cause higher (lower agency costs than a proportional tax if the agent’s marginal tax rate exceeds (is smaller than the marginal tax rate of the principal.

  4. The members of the Agency

    International Nuclear Information System (INIS)

    1994-01-01

    The new members since the last list of Member States of the Agency was issued (INFCIRC/2/Rev.42) are: Armenia, Coratia, the Czech Republic, Lithuania, the Marshall Islands, the Slovak Republic and Uzbekistan. The Attachment to the circular shows the dates on which the 120 States became members of the Agency, as well as those States whose application for membership of the Agency was approved by the General Conference, but who have not yet deposited an instrument of acceptance of the Statute

  5. The Members of the Agency

    International Nuclear Information System (INIS)

    1995-01-01

    The new member since the last list of Member States of the Agency was issued (INFCIRC/2/Rev.44) is Yemen. The Attachment hereto shows the dates on which the 122 States became members of the Agency, as well as the State whose application for membership of the Agency was approved by the General Conference, but which has not yet deposited an instrument of acceptance of the Statute

  6. Japan Sports Arbitration Agency (JSAA

    Directory of Open Access Journals (Sweden)

    Ekaterina P. Rusakova

    2015-12-01

    Full Text Available In this article author analyzes the activities of Japan Sports Arbitration Agency. Author considers the goals, objectives and procedure for dealing with disputes relating to the use of performance-enhancing drugs by athletes. Author study the regulation of Japan Sports Arbitration Agency, to resolve disputes relating to the use of doping, as well as the procedure for application and acceptance of its agency, the choice of arbitrators, counterclaim, protection of evidence.

  7. Regulatory agencies and regulatory risk

    OpenAIRE

    Knieps, Günter; Weiß, Hans-Jörg

    2008-01-01

    The aim of this paper is to show that regulatory risk is due to the discretionary behaviour of regulatory agencies, caused by a too extensive regulatory mandate provided by the legislator. The normative point of reference and a behavioural model of regulatory agencies based on the positive theory of regulation are presented. Regulatory risk with regard to the future behaviour of regulatory agencies is modelled as the consequence of the ex ante uncertainty about the relative influence of inter...

  8. Japan Sports Arbitration Agency (JSAA)

    OpenAIRE

    Ekaterina P. Rusakova

    2015-01-01

    In this article author analyzes the activities of Japan Sports Arbitration Agency. Author considers the goals, objectives and procedure for dealing with disputes relating to the use of performance-enhancing drugs by athletes. Author study the regulation of Japan Sports Arbitration Agency, to resolve disputes relating to the use of doping, as well as the procedure for application and acceptance of its agency, the choice of arbitrators, counterclaim, protection of evidence.

  9. Predictive coding in Agency Detection

    DEFF Research Database (Denmark)

    Andersen, Marc Malmdorf

    2017-01-01

    Agency detection is a central concept in the cognitive science of religion (CSR). Experimental studies, however, have so far failed to lend support to some of the most common predictions that follow from current theories on agency detection. In this article, I argue that predictive coding, a high...... for the effects of culture on the detection of supernatural agency and a range of other religious and spiritual perceptual phenomena....

  10. 77 FR 33216 - Agency Information Collection Activities

    Science.gov (United States)

    2012-06-05

    ... From the Federal Register Online via the Government Publishing Office EQUAL EMPLOYMENT OPPORTUNITY COMMISSION Agency Information Collection Activities AGENCY: Equal Employment Opportunity Commission. ACTION... federal agencies only for evaluating whether an agency's recruitment activities are effectively reaching...

  11. The Members of the Agency

    International Nuclear Information System (INIS)

    1994-01-01

    The new members since the last list of Member States of the Agency was issued (INFCIRC/2/Rev.43) are: Kazakhstan and the former Yugoslav Republic of Macedonia. The Democratic People's Republic of Korea withdrew from membership of the Agency as of 13 June 1994. The Attachment hereto shows the dates on which the 121 States became members of the Agency, as well as those States whose application for membership of the Agency was approved by the General Conference, but who have not yet deposited an instrument of acceptance of the Statute

  12. Credibility Discourse of PR Agencies

    DEFF Research Database (Denmark)

    Isaksson, Maria; Jørgensen, Poul Erik Flyvholm

    2008-01-01

    This research examines the credibility discourse posted on the corporate websites of 60 British, Danish and Norwegian public relations agencies. The purpose was to determine the nature and patterns of the statements of credibility that PR agencies from different cultures have considered instrumen......This research examines the credibility discourse posted on the corporate websites of 60 British, Danish and Norwegian public relations agencies. The purpose was to determine the nature and patterns of the statements of credibility that PR agencies from different cultures have considered...

  13. Agency and Algorithms

    Directory of Open Access Journals (Sweden)

    Hanns Holger Rutz

    2016-11-01

    Full Text Available Although the concept of algorithms has been established a long time ago, their current topicality indicates a shift in the discourse. Classical definitions based on logic seem to be inadequate to describe their aesthetic capabilities. New approaches stress their involvement in material practices as well as their incompleteness. Algorithmic aesthetics can no longer be tied to the static analysis of programs, but must take into account the dynamic and experimental nature of coding practices. It is suggested that the aesthetic objects thus produced articulate something that could be called algorithmicity or the space of algorithmic agency. This is the space or the medium – following Luhmann’s form/medium distinction – where human and machine undergo mutual incursions. In the resulting coupled “extimate” writing process, human initiative and algorithmic speculation cannot be clearly divided out any longer. An observation is attempted of defining aspects of such a medium by drawing a trajectory across a number of sound pieces. The operation of exchange between form and medium I call reconfiguration and it is indicated by this trajectory. 

  14. 28 CFR 83.645 - Federal agency or agency.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Federal agency or agency. 83.645 Section 83.645 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GOVERNMENT-WIDE REQUIREMENTS FOR... means any United States executive department, military department, government corporation, government...

  15. Creating Quality Assurance and International Transparency for Quality Assurance Agencies

    DEFF Research Database (Denmark)

    Kristoffersen, Dorte; Lindeberg, Tobias

    2004-01-01

    The paper presents the experiences gained in the pilot project on mutual recognition conducted by the quality assurance agencies in the Nordic countries and the future perspective for international quality assurance of national quality assurance agencies. The background of the project was the need......, on the one hand, to advance internationalisation of quality assurance of higher education, and on the other hand, allow for the differences in the national approaches to quality assurance. The paper will focus on two issues: first, the strength and weaknesses of the method employed and of the use of the ENQA...

  16. Renewable energy sources: Energy Efficiency Agency

    International Nuclear Information System (INIS)

    Bulgarensky, Mihael

    2004-01-01

    The paper presents the activities of the Energy Efficiency Agency, its main functions, as well as the new legislation stimulating the use of RES, stipulated in the new Energy Law of Bulgaria. The second part of the paper describes the potential of renewable energy in i.e. wind energy; solar energy; biomass energy; hydro energy; geothermal energy; draft of a National Program on RES 2005-2015. The third part describes the main issues of the new ENERGY EFFICIENCY LAW and the established Energy efficiency fund. (Author)

  17. The Agency's accounts for 1968

    International Nuclear Information System (INIS)

    1969-08-01

    General Fund A. Operational programme - 1968: Summary statement for General Fund and Operating Funds as at 31 December 1968 1. Status of funds as at 31 December 1968 2. Summary of obligations and expenditures during 1968 3. Summary of assets and liabilities as at 31 December 1968 B. Operating Fund I: Summary of funds available, obligations and expenditures during 1968 and unobligated balance as at 31 December 1968 C. Operating Fund II: Summary of obligations and expenditures during 1968 and unliquidated obligations by recipient Member States as at 31 December 1968 IV. Special Account: Central Funds-in-Trust Technical Assistance Programme for the Democratic Republic of the Congo: Status of funds as at 31 December 1968 V. Special Account: Saudi Arabian Project Trust Fund: Status of funds as at 31 December 1968 VI. Special Account: Joint research programme of the Agency and the United States Atomic Energy Commission: Status of funds as at 31 December 1968 VII. Special Account: Special fellowships offered by the Union of Soviet Socialist Republics: Status of funds as at 31 December 1968 VIII. Special Account: Venezuelan Project Trust Fund: Status of funds as at 31 December 1968 IX. United Nations Development Programme: Technical Assistance A. Status of funds as at 31 December 1968 B. Obligations incurred: Project costs for the period 1 January to 31 December 1968 X. United Nations Development Programme: Special Fund A. Status of funds for the year ended 31 December 1968 B. Special Fund Executing Agency Overhead Costs: Status of funds as at 31 December 1968 SCHEDULES A. Current accounts and deposit accounts at banks as at 31 December 1968 1. Current accounts at banks 2. Deposit accounts at banks B. Outstanding contributions due from Member States 1. Outstanding contributions to prior years' Regular Budgets as at 31 December 1968 2. Voluntary contributions pledged to the General Fund for 1965, 1966 and 1967, and outstanding as at 31 December 1968 C. Member States

  18. 78 FR 73449 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Science.gov (United States)

    2013-12-06

    ... Substances Pollution Contingency Plan (NCP). This partial deletion pertains to the soil of 1,154 residential...] National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List: Partial Deletion of the Omaha Lead Superfund Site AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule...

  19. The members of the Agency

    International Nuclear Information System (INIS)

    1993-01-01

    The 42nd revision of INFCIRC/2 lists the 113 Member States of the International Atomic Energy Agency as of 1 January 1993. It includes Slovenia as a new Member State as of 21 September 1992, Cambodia replaces the former name ''Democratic Kampuchea'' and Czechoslovakia was deleted as it ceased to be a member of the Agency as of 1 January 1993 (INFCIRC/417)

  20. Embodiment, agency, and attitude change.

    Science.gov (United States)

    Taylor, Cheryl A; Lord, Charles G; Bond, Charles F

    2009-12-01

    Attitude embodiment effects occur when the position or movement of a person's physical body changes the way the person evaluates an object. The present research investigated whether attitude embodiment effects depend more on biomechanical factors or on inferential cues to causal agency. Experiments 1 and 2 showed that actual movements of the physical body are not necessary to create attitude embodiment effects when inferential cues imply agency for another person's physical movements. Experiment 3 showed that actual movements of the physical body are not sufficient to create attitude embodiment effects when inferential cues imply nonagency for those movements. In all 3 experiments, inferential cues to agency played a more important role in attitude embodiment effects than did actual agency, suggesting that theories of embodiment and attitude embodiment need to consider inferential cues to agency alongside biomechanical mechanisms.

  1. 78 FR 1858 - National Environmental Education Advisory Council

    Science.gov (United States)

    2013-01-09

    ..., functions and policies of EPA under the National Environmental Education Act (the Act). The purpose of this... ENVIRONMENTAL PROTECTION AGENCY [FRL-9769-2] National Environmental Education Advisory Council... advice and insights to the Agency on environmental education. DATES: The National Environmental Education...

  2. 48 CFR 6.302-6 - National security.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false National security. 6.302-6... COMPETITION REQUIREMENTS Other Than Full and Open Competition 6.302-6 National security. (a) Authority. (1... for when the disclosure of the agency's needs would compromise the national security unless the agency...

  3. 40 CFR 300.110 - National Response Team.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 27 2010-07-01 2010-07-01 false National Response Team. 300.110... PLAN Responsibility and Organization for Response § 300.110 National Response Team. National planning... agencies named in § 300.175(b). Each agency shall designate a member to the team and sufficient alternates...

  4. 77 FR 11569 - Notice of Intent To Repatriate Cultural Items: USDA Forest Service, Coconino National Forest...

    Science.gov (United States)

    2012-02-27

    ... Cultural Items: USDA Forest Service, Coconino National Forest, Flagstaff, AZ AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The USDA Forest Service, Coconino NF, in consultation with the...

  5. National Security Letters in Foreign Intelligence Investigations: A Glimpse of the Legal Background and Recent Amendments

    National Research Council Canada - National Science Library

    Doyle, Charles

    2006-01-01

    .... These National Security Letters (NSLs) seek customer and consumer transaction information in national security investigations from communications providers, financial institutions, and credit agencies...

  6. Crowd-Sourced Intelligence Agency: Prototyping counterveillance

    Directory of Open Access Journals (Sweden)

    Jennifer Gradecki

    2017-02-01

    Full Text Available This paper discusses how an interactive artwork, the Crowd-Sourced Intelligence Agency (CSIA, can contribute to discussions of Big Data intelligence analytics. The CSIA is a publicly accessible Open Source Intelligence (OSINT system that was constructed using information gathered from technical manuals, research reports, academic papers, leaked documents, and Freedom of Information Act files. Using a visceral heuristic, the CSIA demonstrates how the statistical correlations made by automated classification systems are different from human judgment and can produce false-positives, as well as how the display of information through an interface can affect the judgment of an intelligence agent. The public has the right to ask questions about how a computer program determines if they are a threat to national security and to question the practicality of using statistical pattern recognition algorithms in place of human judgment. Currently, the public’s lack of access to both Big Data and the actual datasets intelligence agencies use to train their classification algorithms keeps the possibility of performing effective sous-dataveillance out of reach. Without this data, the results returned by the CSIA will not be identical to those of intelligence agencies. Because we have replicated how OSINT is processed, however, our results will resemble the type of results and mistakes made by OSINT systems. The CSIA takes some initial steps toward contributing to an informed public debate about large-scale monitoring of open source, social media data and provides a prototype for counterveillance and sousveillance tools for citizens.

  7. 76 FR 38684 - Minor Boundary Revision at Virgin Islands National Park

    Science.gov (United States)

    2011-07-01

    ... DEPARTMENT OF THE INTERIOR National Park Service Minor Boundary Revision at Virgin Islands National Park AGENCY: National Park Service, Interior. ACTION: Notification of boundary revision. SUMMARY... National Park is modified to include an [[Page 38685

  8. 75 FR 6700 - National Park Service Concessions Management Advisory Board Reestablishment

    Science.gov (United States)

    2010-02-10

    ... DEPARTMENT OF THE INTERIOR National Park Service Concessions Management Advisory Board Reestablishment AGENCY: National Park Service, Interior. ACTION: Notice of reestablishment of the National Park... administratively reestablish the National Park Service Concessions Management Advisory Board. This action is...

  9. 76 FR 39443 - National Environmental Policy Act; Santa Susana Field Laboratory

    Science.gov (United States)

    2011-07-06

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-058)] National Environmental Policy Act; Santa Susana Field Laboratory AGENCY: National Aeronautics and Space Administration (NASA). ACTION... Laboratory (SSFL), Ventura County, California. SUMMARY: Pursuant to the National Environmental Policy Act...

  10. 75 FR 52587 - 2009 Fatality Analysis Reporting System (FARS)/National Automotive Sampling System General...

    Science.gov (United States)

    2010-08-26

    ... National Highway Traffic Safety Administration 2009 Fatality Analysis Reporting System (FARS)/National Automotive Sampling System General Estimates System (NASS GES) Updates AGENCY: National Highway Traffic... Traffic Safety Administration (NHTSA)--2009 Fatality Analysis Reporting System (FARS) & National...

  11. 78 FR 38077 - National Industrial Security Program Policy Advisory Committee (NISPPAC)

    Science.gov (United States)

    2013-06-25

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Information Security Oversight Office [NARA-13-0030] National Industrial Security Program Policy Advisory Committee (NISPPAC) AGENCY: National Archives and... following committee meeting to discuss National Industrial Security Program policy matters. DATES: The...

  12. 78 FR 14549 - National Contact Center; Information Collection; National Contact Center Customer Evaluation Survey

    Science.gov (United States)

    2013-03-06

    ...] National Contact Center; Information Collection; National Contact Center Customer Evaluation Survey AGENCY... National Contact Center customer evaluation surveys. In this request, the previously approved surveys have... several months. These temporary surveys will allow the National Contact Center to compare its customer...

  13. 75 FR 14454 - National Protection and Programs Directorate; National Infrastructure Advisory Council

    Science.gov (United States)

    2010-03-25

    ..., Assistant Designated Federal Officer, National Infrastructure Advisory Council. BILLING CODE 9110-9P-P ... SECURITY National Protection and Programs Directorate; National Infrastructure Advisory Council AGENCY... Council Meeting. SUMMARY: The National Infrastructure Advisory Council (NIAC) will meet on Tuesday, April...

  14. 78 FR 3909 - Big Oaks National Wildlife Refuge, IN; Glacial Ridge National Wildlife Refuge, MN; Northern...

    Science.gov (United States)

    2013-01-17

    ... Fish and Wildlife Service Big Oaks National Wildlife Refuge, IN; Glacial Ridge National Wildlife Refuge, MN; Northern Tallgrass Prairie National Wildlife Refuge, MN; Whittlesey Creek National Wildlife Refuge, WI AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of intent; request for comments...

  15. 77 FR 15052 - National Ocean Council-National Ocean Policy Draft Implementation Plan

    Science.gov (United States)

    2012-03-14

    ... QUALITY National Ocean Council--National Ocean Policy Draft Implementation Plan AGENCY: Council on... essential to public health and national security. Next, public comments on the draft Implementation Plan... Executive Order 13547 establishing a National Policy for the Stewardship of the Ocean, our Coasts, and the...

  16. The Federal Emergency Management Agency's National Incident Management System

    Science.gov (United States)

    The NIMS provides an integrated framework defining the roles and responsibilities of federal, state and local first responders, developed with responders from different jurisdictions and disciplines, to better work together during emergency events.

  17. Malaysian Nuclear Agency; Annual report 2014

    International Nuclear Information System (INIS)

    2009-01-01

    The establishment of Malaysian Nuclear Agency (Nuclear Malaysia) was mooted from idea of the then Malaysia's Deputy Prime Minister, Tun Dr. Ismail Dato Abdul Rahman, that Malaysia should play a role in the development of nuclear science and technology for peaceful purposes. The Centre for Application of Nuclear Energy (CRANE) was the entity to mark the of Malaysia's nuclear programme, focussing on manpower development for a nuclear power programme to provide an option for energy source, following the worldwide oil crisis of the early 1970s. The Cabinet officially approved the establishment of the Tun Ismail Atomic Research Centre (PUSPATI), under the Ministry of Science, Technology and the environment on 19 September 1972. The era of nuclear research in Malaysia began with the historic event signified by the Reaktor TRIGA PUSPATI reaching its first criticality on 28 June 1982. When PUSPATI was placed under the auspices of the Prime Ministers Department, it assumed the name Nuclear Energy Unit (UTN). The Nuclear Energy Unit was later placed under the Minister of Science, Technology and the Environment. In line with the national development, the institute was name Malaysian Institute for Nuclear Technology Research (MINT) on 10 August 1994. To reflect its vision, mission, objectives and activities in the challenging world, a new identity was established, and was officially named as Malaysian Nuclear Agency (Nuclear Malaysia) on 28 September 2006. Nuclear Malaysia, is strategically located nearby the government administration, centre Putrajaya, and Cyberjaya. These annual report highlights all the activities that have been through by the agency in 2014. All the achievements and triumph were highlights in this annual report. It also contained all the agency planning during 2014 to fulfill the objectives, mission and vision to become main players in nuclear research in Malaysia. Finally, there also highlights some publications contribute by all the researchers

  18. Malaysian Nuclear Agency: Annual report 2008

    International Nuclear Information System (INIS)

    2008-01-01

    The establishment of Malaysian Nuclear Agency (Nuclear Malaysia) was mooted from idea of the then Malaysia's Deputy Prime Minister, Tun Dr. Ismail Dato Abdul Rahman, that Malaysia should play a role in the development of nuclear science and technology for peaceful purposes. The Centre for Application of Nuclear Energy (CRANE) was the entity to mark the of Malaysia's nuclear programme, focussing on manpower development for a nuclear power programme to provide an option for energy source, following the worldwide oil crisis of the early 1970s. The Cabinet officially approved the establishment of the Tun Ismail Atomic Research Centre (PUSPATI), under the Ministry of Science, Technology and the environment on 19 September 1972. The era of nuclear research in Malaysia began with the historic event signified by the Reaktor TRIGA PUSPATI reaching its first criticality on 28 June 1982. When PUSPATI was placed under the auspices of the Prime Ministers Department, it assumed the name Nuclear Energy Unit (UTN). The Nuclear Energy Unit was later placed under the Minister of Science, Technology and the Environment. In line with the national development, the institute was name Malaysian Institute for Nuclear Technology Research (MINT) on 10 August 1994. To reflect its vision, mission, objectives and activities in the challenging world, a new identity was established, and was officially named as Malaysian Nuclear Agency (Nuclear Malaysia) on 28 September 2006. Nuclear Malaysia, is strategically located nearby the government administration, centre Putrajaya, and Cyberjaya. These annual report highlights all the activities that have been through by the agency in 2008. All the achievements and triumph were highlights in this annual report. It also contained all the agency planning during 2008 to fulfill the objectives, mission and vision to become main players in nuclear research in Malaysia. Finally, there also highlights some publications contribute by all the researchers from

  19. Malaysian Nuclear Agency; Annual report 2013

    International Nuclear Information System (INIS)

    2013-01-01

    The establishment of Malaysian Nuclear Agency (Nuclear Malaysia) was mooted from idea of the then Malaysia's Deputy Prime Minister, Tun Dr. Ismail Dato Abdul Rahman, that Malaysia should play a role in the development of nuclear science and technology for peaceful purposes. The Centre for Application of Nuclear Energy (CRANE) was the entity to mark the of Malaysia's nuclear programme, focussing on manpower development for a nuclear power programme to provide an option for energy source, following the worldwide oil crisis of the early 1970s. The Cabinet officially approved the establishment of the Tun Ismail Atomic Research Centre (PUSPATI), under the Ministry of Science, Technology and the environment on 19 September 1972. The era of nuclear research in Malaysia began with the historic event signified by the Reaktor TRIGA PUSPATI reaching its first criticality on 28 June 1982. When PUSPATI was placed under the auspices of the Prime Ministers Department, it assumed the name Nuclear Energy Unit (UTN). The Nuclear Energy Unit was later placed under the Minister of Science, Technology and the Environment. In line with the national development, the institute was name Malaysian Institute for Nuclear Technology Research (MINT) on 10 August 1994. To reflect its vision, mission, objectives and activities in the challenging world, a new identity was established, and was officially named as Malaysian Nuclear Agency (Nuclear Malaysia) on 28 September 2006. Nuclear Malaysia, is strategically located nearby the government administration, centre Putrajaya, and Cyberjaya. These annual report highlights all the activities that have been through by the agency in 2013. All the achievements and triumph were highlights in this annual report. It also contained all the agency planning during 2013 to fulfill the objectives, mission and vision to become main players in nuclear research in Malaysia. Finally, there also highlights some publications contribute by all the researchers

  20. Malaysian Nuclear Agency: Annual report 2010

    International Nuclear Information System (INIS)

    2010-01-01

    The establishment of Malaysian Nuclear Agency (Nuclear Malaysia) was mooted from idea of the then Malaysia's Deputy Prime Minister, Tun Dr. Ismail Dato Abdul Rahman, that Malaysia should play a role in the development of nuclear science and technology for peaceful purposes. The Centre for Application of Nuclear Energy (CRANE) was the entity to mark the of Malaysia's nuclear programme, focussing on manpower development for a nuclear power programme to provide an option for energy source, following the worldwide oil crisis of the early 1970s. The Cabinet officially approved the establishment of the Tun Ismail Atomic Research Centre (PUSPATI), under the Ministry of Science, Technology and the environment on 19 September 1972. The era of nuclear research in Malaysia began with the historic event signified by the Reaktor TRIGA PUSPATI reaching its first criticality on 28 June 1982. When PUSPATI was placed under the auspices of the Prime Ministers Department, it assumed the name Nuclear Energy Unit (UTN). The Nuclear Energy Unit was later placed under the Minister of Science, Technology and the Environment. In line with the national development, the institute was name Malaysian Institute for Nuclear Technology Research (MINT) on 10 August 1994. To reflect its vision, mission, objectives and activities in the challenging world, a new identity was established, and was officially named as Malaysian Nuclear Agency (Nuclear Malaysia) on 28 September 2006. Nuclear Malaysia, is strategically located nearby the government administration, centre Putrajaya, and Cyberjaya. These annual report highlights all the activities that have been through by the agency in 2010. All the achievements and triumph were highlights in this annual report. It also contained all the agency planning during 2010 to fulfill the objectives, mission and vision to become main players in nuclear research in Malaysia. Finally, there also highlights some publications contribute by all the researchers from